Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 67.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Extravillous trophoblasts: 71.3;Hepatocytes: 29.3;Spermatogonia: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.3 2.8 6.2 1.9 6.8 0.3 4.7 3.8 9.8 9.8 11.3 6.2 1.6 10.5 5.9 2.6 6.3 3.9 2.7 6.5 6.7 6.8 67.1 4.9 0.7 5.8 5.6 4.7 5.6 6.0 6.1 1.9 6.5 14.4 5.0 11.8 1.7 5.3 4.0 1.4 2.3 7.3 4.8 1.7 3.6 8.2 6.1 1.5 7.5 2.4 0.8 6.4 5.7 8.7 3.5 8.5 25.0 0.0 4.9 18.9 9.0 8.7 4.2 4.9 5.0 8.4 1.0 0.1 1.4 9.8 6.5 2.9 11.3 4.1 3.4 0.0 9.7 0.0 10.0 14.0 3.9 0.1 3.8 7.7 2.5 4.0 5.1 13.5 4.7 11.4 1.5 0.1 19.0 8.9 4.3 0.1 19.0 9.6 7.6 0.0 7.8 0.0 4.4 15.3 20.1 23.5 7.0 1.7 8.5 8.0 0.1 1.7 3.2 12.5 13.4 14.3 13.9 0.1 0.0 0.1 12.5 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.8 3.8 9.8 6.5 6.7 5.8 5.6 6.5 4.8 6.1 8.7 0.9 0.0 5.9 22.2 0.3 0.9 2.8 0.9 6.2 6.0 3.9 1.0 1.2 1.5 2.1 0.0 2.1 2.8 0.0 0.7 0.0 1.6 0.5 3.7 7.4 0.7 6.7 0.0 15.4 2.2 71.3 3.2 3.1 6.0 0.0 6.2 0.7 29.3 1.6 0.0 13.6 2.8 0.0 0.3 0.9 1.4 1.2 0.4 1.8 5.6 0.0 2.7 0.0 17.6 14.0 1.1 1.6 2.2 0.0 4.0 0.2 8.4 8.5 9.1 6.6 3.9 4.2 14.5 27.1 3.0 0.4 5.6 0.3 3.3 3.1 1.8 AAK1 "DKFZp686K16132, KIAA1048" ENSG00000115977 "AP2 associated kinase 1" Q2M2I8 2 69457997-69674349 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 89.7" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 777.7;Rod photoreceptor cells: 640.8" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 6 "cerebral cortex: 31.0" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017931, HPA020289" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Cytosol "HPA017931: AB_1844406, HPA020289: AB_1844407" "unprognostic (2.11e-3)" "unprognostic (3.18e-2)" "unprognostic (3.67e-1)" "unprognostic (1.01e-3)" "unprognostic (5.06e-2)" "unprognostic (4.04e-2)" "unprognostic (4.23e-2)" "unprognostic (1.14e-1)" "unprognostic (3.52e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.24e-1)" "unprognostic (7.65e-2)" "unprognostic (4.18e-2)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.76e-3)" "unprognostic (1.18e-1)" 9.1 12.6 0.3 8.1 0.6 12.0 8.1 0.9 31.0 7.1 0.0 7.0 4.6 9.9 9.9 7.4 7.5 5.4 20.4 2.9 0.0 10.5 5.1 10.3 9.0 4.7 2.9 5.5 13.1 89.7 13.7 9.9 3.5 8.6 6.3 28.2 6.7 8.2 13.0 6.3 8.5 7.6 0.0 8.6 12.6 6.7 4.8 13.2 23.4 6.7 7.7 7.8 7.1 4.8 25.1 15.3 14.6 12.3 13.7 14.3 41.0 19.4 16.8 12.0 11.3 15.6 10.0 0.9 4.6 27.6 16.5 11.4 11.7 11.4 27.1 20.6 4.4 13.3 9.0 10.0 11.7 9.5 31.3 12.9 9.6 23.7 30.9 10.2 27.4 12.3 3.2 14.1 22.5 3.7 8.8 5.6 6.4 4.9 8.3 5.8 13.8 2.2 10.0 51.0 4.2 6.6 12.0 8.8 10.2 9.9 5.3 12.9 25.6 26.4 17.5 19.7 19.4 12.9 3.9 1.5 23.0 16.0 19.1 1.4 0.5 0.2 1.4 0.2 1.4 0.1 1.3 1.0 0.3 0.3 1.7 1.5 1.5 1.1 2.2 0.2 1.0 0.5 0.3 0.6 0.9 31.0 2.9 0.0 4.7 2.9 3.5 0.0 4.8 4.8 54.6 35.3 34.2 77.7 13.4 15.9 20.8 15.9 32.5 254.4 42.2 40.9 86.7 102.9 19.3 143.5 777.7 81.6 149.1 130.6 43.0 46.0 23.9 36.6 67.4 56.0 72.1 35.3 265.8 67.4 56.3 29.5 44.9 65.7 21.0 24.4 118.2 38.2 62.4 306.2 327.7 31.6 12.2 128.8 23.5 32.7 38.2 67.1 10.6 156.4 72.7 53.2 252.4 147.8 113.9 55.9 76.3 46.6 57.4 42.1 56.0 90.0 10.7 640.8 19.7 26.7 45.5 46.9 59.3 23.3 9.9 213.3 158.1 33.6 21.7 49.0 ABCA12 "DKFZP434G232, ICR2B, LI2" ENSG00000144452 "ATP binding cassette subfamily A member 12" Q86UK0 2 214931542-215138626 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "breast: 5.7;skin 1: 20.7" "Group enriched" "Detected in some" 4 "Basal keratinocytes: 12.9;Suprabasal keratinocytes: 38.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "hTCEpi: 38.7;SK-BR-3: 18.3;T-47d: 9.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "cerebral cortex: 1.0;hippocampal formation: 1.1" HPA078239 Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "Nucleoli, Cytosol" "HPA078239: AB_2732373" "unprognostic (6.12e-2)" "unprognostic (4.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.03e-1)" "unprognostic (2.49e-1)" "unprognostic (2.13e-1)" "unprognostic (2.09e-4)" "unprognostic (6.52e-3)" "unprognostic (3.75e-2)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (2.50e-2)" "unprognostic (7.69e-2)" "unprognostic (5.92e-2)" "unprognostic (2.64e-2)" "unprognostic (2.36e-1)" "unprognostic (5.08e-2)" 0.0 0.0 0.0 0.1 0.1 0.0 5.7 0.0 0.1 1.3 0.0 0.3 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.3 0.2 0.2 0.0 0.0 20.7 0.0 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 2.8 0.3 3.9 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 38.7 0.0 2.8 0.0 0.0 0.0 0.0 0.2 0.2 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.4 0.5 0.1 2.7 0.0 18.3 0.0 0.2 9.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.0 12.9 0.9 6.0 0.0 0.2 1.0 0.5 0.5 0.0 5.1 0.0 0.0 1.1 0.0 3.0 0.0 0.1 2.2 2.6 0.3 0.1 0.0 0.0 1.4 0.0 2.7 0.1 1.5 3.7 0.0 0.5 0.0 0.0 0.4 1.7 2.9 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 1.5 0.6 1.9 0.0 0.7 0.0 1.0 0.0 0.1 3.1 0.2 0.0 0.0 0.2 0.7 0.4 2.2 38.6 3.4 0.0 0.1 0.9 2.7 ABCA7 ABCX ENSG00000064687 "ATP binding cassette subfamily A member 7" Q8IZY2 19 1039997-1065572 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Phagocytosis, Transport" Translocase "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;pituitary gland: 28.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Bipolar cells: 70.6;Cone photoreceptor cells: 175.2;Extravillous trophoblasts: 303.3;Rod photoreceptor cells: 149.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 20.4;HMC-1: 40.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in some" HPA041564 Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Golgi apparatus, Plasma membrane" "Cell Junctions" "HPA041564: AB_2677550" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (7.26e-4)" "prognostic favorable (1.12e-4)" "unprognostic (8.88e-2)" "unprognostic (1.13e-2)" "unprognostic (2.25e-1)" "unprognostic (4.00e-2)" "unprognostic (1.04e-1)" "unprognostic (2.24e-2)" "unprognostic (1.51e-3)" "unprognostic (3.68e-2)" "unprognostic (8.99e-3)" "unprognostic (2.08e-2)" "unprognostic (3.66e-1)" "unprognostic (7.88e-2)" "unprognostic (7.85e-2)" 4.4 3.0 3.4 5.5 3.9 27.4 3.3 4.0 6.1 3.2 11.5 3.8 2.3 1.2 0.2 7.6 2.1 2.1 3.1 3.6 3.7 6.4 4.2 9.5 8.5 5.8 4.5 0.5 7.7 2.7 28.7 1.2 5.3 5.3 1.2 25.5 8.6 1.1 3.8 5.9 10.1 0.5 3.0 26.6 3.8 1.7 4.1 10.0 5.7 0.3 3.2 2.3 2.8 3.2 4.7 6.4 0.5 4.4 7.2 2.2 7.3 0.8 1.0 0.4 0.6 5.2 2.8 13.9 5.6 1.3 0.6 8.0 1.3 6.2 0.4 10.2 2.5 6.7 20.4 5.6 1.8 3.9 40.3 3.8 1.8 0.9 1.2 4.4 1.4 7.7 10.2 6.9 1.3 2.2 4.3 2.2 0.9 3.3 2.5 3.1 0.8 11.6 3.8 6.0 0.3 1.3 8.2 1.9 1.2 1.1 4.6 7.1 2.2 0.4 1.6 3.7 0.8 9.9 6.6 5.7 2.1 7.4 2.0 2.8 1.4 5.9 1.8 1.2 1.1 0.6 0.9 1.2 2.1 0.9 0.8 1.5 3.3 1.1 1.3 7.3 0.4 1.3 3.4 3.9 4.0 6.1 3.6 3.7 5.8 4.5 5.3 3.0 4.1 3.2 4.1 73.7 21.9 8.5 13.2 3.3 0.8 10.7 5.2 70.6 4.8 2.2 6.0 4.3 14.0 5.5 175.2 4.6 9.1 14.7 1.9 2.7 7.3 8.9 1.4 2.9 3.5 13.3 12.9 2.5 303.3 1.5 5.6 6.9 10.1 2.0 2.5 4.9 7.9 15.2 11.5 4.7 16.2 12.6 7.5 4.8 0.0 12.7 0.0 4.7 19.6 13.1 9.2 1.5 2.4 7.0 9.6 0.0 12.0 1.5 1.7 1.3 17.5 149.1 0.0 2.7 2.7 0.7 2.0 6.6 3.4 25.7 12.6 1.0 5.3 1.9 ABCB1 "ABC20, CD243, CLCS, GP170, MDR1, P-gp, PGY1" ENSG00000085563 "ATP binding cassette subfamily B member 1" P08183 7 87503017-87713323 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 101.7;intestine: 70.7" "Cell type enhanced" "Detected in many" "Cholangiocytes: 95.8;Distal enterocytes: 109.9;Microglial cells: 570.6;Paneth cells: 106.2;Proximal enterocytes: 204.6" "Cancer enhanced" "Detected in many" "renal cancer: 14.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 27.2;NK-cell: 17.9" "Group enriched" "Detected in many" 9 "NK-cells: 17.9;T-cells: 27.2" "Cell line enhanced" "Detected in some" "CACO-2: 67.3;HEK 293: 20.4;HEL: 37.7;Hep G2: 18.5;RPTEC TERT1: 24.2;SH-SY5Y: 78.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 12.2" "CAB001716, HPA002199, HPA074614" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Plasma membrane" "Focal adhesion sites" "CAB001716: , HPA002199: AB_1844428, HPA074614: " "unprognostic (5.38e-3)" "unprognostic (2.45e-2)" "unprognostic (1.42e-1)" "unprognostic (1.06e-1)" "unprognostic (2.25e-2)" "unprognostic (9.99e-5)" "unprognostic (2.23e-3)" "unprognostic (5.65e-3)" "unprognostic (1.14e-1)" "unprognostic (5.17e-2)" "prognostic favorable (3.33e-4)" "unprognostic (5.19e-1)" "prognostic favorable (2.95e-4)" "unprognostic (2.06e-1)" "unprognostic (1.50e-1)" "unprognostic (3.83e-1)" "unprognostic (6.12e-2)" 2.6 101.7 14.1 3.9 13.6 1.9 3.6 13.7 17.6 6.4 5.3 16.6 26.4 11.0 3.6 3.1 5.0 15.5 1.9 15.3 15.6 33.7 28.0 6.4 3.2 17.6 14.4 2.2 2.0 1.4 0.5 2.3 19.7 4.2 18.2 2.2 1.2 3.1 0.2 1.5 70.7 9.8 15.1 4.2 2.1 0.9 19.3 2.7 1.9 1.4 3.5 3.6 1.7 14.3 0.0 0.0 3.7 0.0 0.0 0.0 0.1 0.1 4.3 0.0 0.0 67.3 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 20.4 37.7 4.2 18.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 3.2 0.0 0.1 0.0 0.2 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 24.2 0.2 0.9 78.9 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.0 4.0 0.0 0.9 7.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 11.1 0.0 27.2 0.8 2.7 6.8 0.0 2.5 1.7 6.6 0.2 17.9 0.0 0.1 0.0 2.5 14.1 13.6 13.7 17.6 15.3 15.6 17.6 14.4 19.7 15.1 19.3 14.3 17.1 0.0 3.0 3.9 9.9 0.8 0.1 0.0 1.2 1.9 0.4 3.9 3.0 95.8 0.6 49.7 0.0 5.8 24.7 109.9 5.9 13.8 27.3 0.6 0.6 52.9 0.0 7.8 16.1 1.9 0.2 3.7 0.0 0.7 3.8 0.3 2.5 38.4 0.4 0.0 11.4 15.8 0.0 0.6 1.2 3.8 0.9 1.6 0.0 570.6 0.2 0.2 32.0 6.0 3.2 8.1 106.2 0.0 4.6 0.2 204.6 57.7 0.7 1.1 0.0 0.4 1.3 0.4 0.9 0.2 0.6 9.9 24.5 0.1 19.9 0.3 ABCB11 "ABC16, BSEP, PFIC-2, PFIC2, PGY4, SPGP" ENSG00000073734 "ATP binding cassette subfamily B member 11" O95342 2 168915498-169031324 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 80.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 41.7;Alveolar cells type 2: 44.1;Club cells: 19.3;Early spermatids: 16.5;granulocytes: 24.0;Hepatocytes: 20.4" "Cancer enriched" "Detected in single" 87 "liver cancer: 6.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.6;RT4: 1.6;TIME: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA019035 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 24: NB-4 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Plasma membrane, Cytosol" "HPA019035: AB_1844429" "unprognostic (7.78e-2)" "unprognostic (3.92e-1)" "unprognostic (8.31e-2)" "unprognostic (2.56e-1)" "unprognostic (1.13e-1)" "unprognostic (5.10e-2)" "unprognostic (1.00e-2)" "unprognostic (9.71e-2)" "unprognostic (1.18e-1)" "unprognostic (1.72e-2)" "unprognostic (5.64e-3)" "unprognostic (3.71e-1)" "unprognostic (5.26e-6)" "unprognostic (7.12e-2)" "unprognostic (1.82e-1)" "unprognostic (1.94e-1)" 1.5 0.0 0.3 0.1 0.3 0.0 0.6 0.3 0.5 0.0 0.2 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 80.8 0.0 0.1 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.4 0.1 0.0 0.0 1.1 0.0 0.0 0.3 0.1 0.0 6.2 0.2 0.0 0.0 0.0 0.1 1.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.4 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.5 0.2 0.2 1.0 0.6 0.5 0.3 0.2 0.3 0.0 41.7 44.1 1.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 19.3 0.0 0.0 0.0 0.0 0.7 0.0 0.1 16.5 0.1 0.0 1.8 0.0 2.7 0.8 0.0 0.0 6.6 0.0 0.0 24.0 0.0 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.3 0.0 9.1 0.0 3.8 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.1 0.0 0.0 8.9 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.6 ABCB4 "GBD1, MDR2, MDR3, PFIC-3, PGY3" ENSG00000005471 "ATP binding cassette subfamily B member 4" P21439 7 87401696-87480435 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 123.2" "Cell type enriched" "Detected in some" 6 "Hepatocytes: 256.1" "Cancer enriched" "Detected in some" 11 "liver cancer: 16.3" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory B-cell: 4.4;naive B-cell: 8.1" "Lineage enriched" "Detected in many" 7 "B-cells: 8.1" "Group enriched" "Detected in some" 5 "SH-SY5Y: 12.9;WM-115: 25.7" "Low region specificity" "Detected in many" "HPA049395, HPA053288" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 17: WM-115 - Nervous system development" "Cluster 2: Hepatocytes - Metabolism" "Nucleoplasm, Plasma membrane, Actin filaments" "Focal adhesion sites" "HPA049395: AB_2680745, HPA053288: AB_2682102" "unprognostic (7.92e-2)" "unprognostic (8.87e-2)" "unprognostic (1.97e-1)" "unprognostic (1.90e-1)" "unprognostic (8.95e-2)" "unprognostic (1.06e-2)" "unprognostic (2.35e-3)" "unprognostic (9.91e-2)" "unprognostic (3.53e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-3)" "unprognostic (8.43e-2)" "unprognostic (2.83e-2)" "unprognostic (8.01e-3)" "unprognostic (7.12e-2)" "unprognostic (2.11e-2)" "unprognostic (2.47e-1)" 0.7 7.4 0.8 2.5 0.6 0.9 0.5 0.6 0.9 0.3 0.4 1.1 0.4 0.2 0.6 0.6 0.2 0.8 6.6 0.8 0.6 0.6 123.2 0.2 5.9 0.9 0.6 0.4 0.1 0.0 0.2 0.2 1.0 0.5 1.2 0.4 0.6 0.4 7.5 1.4 2.1 0.3 0.6 5.0 0.6 1.0 0.7 0.7 0.5 4.8 5.2 1.2 0.5 0.7 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 0.4 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.2 12.9 0.0 0.6 2.6 0.5 0.2 0.6 0.0 0.2 1.7 0.1 0.0 0.0 0.0 3.2 0.2 0.0 25.7 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 1.2 8.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.8 0.6 0.6 0.9 0.8 0.6 0.9 0.6 1.0 0.6 0.7 0.7 1.3 0.0 0.5 0.3 22.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 1.8 0.0 1.1 0.1 0.2 0.0 0.1 0.6 0.2 0.2 1.0 0.0 0.4 0.6 0.0 0.3 2.0 0.0 0.2 0.0 0.0 3.3 256.1 0.5 38.7 1.8 0.0 0.0 5.0 1.2 0.4 0.0 1.0 10.6 3.7 0.1 0.0 0.0 0.5 0.0 0.1 0.1 0.4 0.3 0.0 0.5 0.7 0.0 0.2 0.0 0.6 1.2 1.2 0.2 0.0 0.4 0.1 0.7 0.0 0.2 0.0 ABCB6 "EST45597, MTABC3, umat" ENSG00000115657 "ATP binding cassette subfamily B member 6 (Langereis blood group)" Q9NP58 2 219209772-219218994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport Translocase "Disease variant, Dyskeratosis congenita, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Astrocytes: 14.7;Excitatory neurons: 12.9;Gastric mucus-secreting cells: 5.1;Inhibitory neurons: 10.9;Oligodendrocyte precursor cells: 13.6;Oligodendrocytes: 5.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 65.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046723, HPA058011" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Nucleoplasm, Plasma membrane, Mitochondria, Cytosol" "HPA046723: AB_10960288, HPA058011: AB_2683578" "unprognostic (8.04e-2)" "unprognostic (3.22e-2)" "unprognostic (4.53e-3)" "unprognostic (3.19e-2)" "unprognostic (2.55e-1)" "unprognostic (9.11e-2)" "prognostic unfavorable (9.45e-7)" "unprognostic (2.26e-1)" "unprognostic (3.62e-2)" "unprognostic (1.53e-1)" "unprognostic (1.18e-4)" "unprognostic (3.02e-3)" "prognostic unfavorable (1.52e-7)" "unprognostic (1.51e-1)" "unprognostic (9.55e-2)" "unprognostic (7.75e-2)" "unprognostic (2.30e-1)" 10.2 8.7 4.3 3.4 3.9 10.4 7.6 3.2 4.6 7.7 4.4 6.5 6.9 8.4 8.2 11.4 9.6 7.1 8.5 4.0 5.1 5.2 15.9 5.9 1.9 4.4 4.2 12.9 5.7 4.8 6.0 3.1 6.2 8.0 3.3 3.0 6.2 8.6 30.4 6.8 6.3 7.9 4.1 3.9 7.9 18.0 5.7 2.6 10.7 9.8 2.9 14.9 7.9 5.0 0.3 22.9 4.7 28.8 30.8 11.1 27.6 8.5 7.9 9.2 9.2 35.5 5.0 0.3 42.8 8.6 5.0 49.1 0.6 3.6 3.0 15.0 4.7 36.3 24.9 65.8 37.0 0.0 12.0 16.3 4.2 6.2 0.1 13.9 16.3 4.8 31.4 4.4 6.3 12.0 2.3 0.1 7.2 53.6 9.2 12.3 14.3 1.6 5.1 0.4 16.6 17.8 17.6 41.4 18.7 17.4 12.4 0.8 7.5 12.5 0.5 16.9 10.3 11.2 9.6 0.1 14.0 0.4 17.0 0.7 0.4 0.0 0.7 0.4 0.2 1.0 0.5 0.2 0.3 0.8 1.2 0.8 0.0 0.4 0.3 2.3 0.5 1.0 4.3 3.9 3.2 4.6 4.0 5.1 4.4 4.2 6.2 4.1 5.7 5.0 0.2 0.0 0.0 14.7 0.3 0.3 0.0 0.5 1.2 1.0 0.2 0.0 0.2 0.0 1.3 0.0 0.0 0.2 0.2 0.1 0.0 0.8 1.2 0.3 0.6 0.4 0.0 1.3 12.9 0.0 0.1 0.7 5.1 0.2 0.0 0.5 0.0 0.4 0.1 0.0 10.9 0.3 0.0 0.3 0.4 1.0 0.3 0.3 0.0 3.7 0.0 0.3 0.0 13.6 5.6 0.3 0.0 0.4 0.5 0.0 0.5 0.2 2.2 0.8 0.0 0.4 0.3 1.0 0.3 2.8 0.3 0.3 0.1 0.4 0.2 0.1 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 ABCC4 "EST170205, MOAT-B, MOATB, MRP4" ENSG00000125257 "ATP binding cassette subfamily C member 4" O15439 13 95019835-95301475 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 41.1" "Cell type enhanced" "Detected in many" "Erythroid cells: 51.3;granulocytes: 53.9;Microglial cells: 203.3" "Cancer enriched" "Detected in all" 8 "prostate cancer: 90.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in many" 4 "HEL: 245.7;HMC-1: 256.3;RPTEC TERT1: 69.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002476 Enhanced Supported "Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoli, Golgi apparatus" "HPA002476: AB_1844434" "unprognostic (8.77e-2)" "unprognostic (1.94e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (9.89e-4)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (7.45e-3)" "unprognostic (2.40e-2)" "unprognostic (9.96e-2)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.55e-2)" "prognostic favorable (2.25e-10)" "unprognostic (7.44e-3)" "unprognostic (1.67e-1)" "unprognostic (5.55e-2)" "unprognostic (2.35e-2)" 2.2 1.3 2.5 6.1 2.3 4.1 6.9 2.5 2.5 4.9 7.2 9.2 4.9 3.4 18.8 2.0 10.2 6.1 2.0 2.3 5.4 18.0 1.3 7.6 3.9 4.3 3.7 3.7 3.3 22.5 1.4 2.1 4.6 41.1 8.5 0.9 1.5 5.5 5.3 2.9 5.4 6.3 4.9 4.1 5.2 4.7 3.2 3.9 7.7 1.7 6.3 15.4 1.8 5.1 18.5 31.7 5.3 9.4 9.5 12.3 1.3 14.4 14.3 12.6 10.9 43.8 13.2 10.2 9.3 19.5 9.0 24.0 7.9 7.1 15.8 30.7 12.1 245.7 8.8 8.8 19.2 28.6 256.3 9.4 3.2 9.1 18.5 17.9 16.4 11.3 25.8 0.4 17.1 5.9 5.4 4.6 6.2 22.3 7.9 7.7 14.3 26.9 69.3 40.4 12.5 9.3 4.8 1.2 10.1 5.9 0.0 15.1 27.0 13.3 8.6 11.2 17.3 0.1 0.0 4.0 25.4 16.0 6.6 0.2 0.5 0.2 1.3 0.6 1.1 1.4 1.0 1.5 1.8 1.6 0.6 1.5 0.3 1.9 2.3 0.3 1.5 1.3 2.5 2.3 2.5 2.5 2.3 5.4 4.3 3.7 4.6 4.9 3.2 5.1 4.6 9.6 32.7 28.4 5.8 4.2 7.0 7.3 4.0 0.1 0.6 0.6 4.5 8.6 9.1 23.9 22.9 0.1 2.0 2.7 0.0 6.9 3.8 4.2 11.3 19.8 0.0 51.3 13.6 3.1 0.4 5.7 6.1 6.0 53.9 9.5 2.9 0.6 4.5 0.0 10.3 4.0 0.0 2.5 8.1 2.0 6.8 10.7 1.8 203.3 13.5 0.5 4.1 16.1 2.5 2.9 8.3 1.9 8.3 27.1 0.5 26.4 4.7 0.8 0.0 8.2 3.1 0.9 8.3 3.4 7.5 0.3 6.4 17.3 9.2 4.5 ABCC5 "EST277145, MOAT-C, MRP5, SMRP" ENSG00000114770 "ATP binding cassette subfamily C member 5" O15440 3 183919934-184017939 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 167.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 196.0;Inhibitory neurons: 122.8;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 136.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044067, HPA052295" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 54: Non-specific - Microtubule organization" "Cluster 15: RT4 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA044067: AB_2678797, HPA052295: AB_2681789" "unprognostic (9.39e-2)" "unprognostic (6.23e-3)" "unprognostic (3.83e-2)" "unprognostic (1.10e-3)" "unprognostic (2.28e-2)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (4.46e-2)" "unprognostic (6.07e-3)" "unprognostic (1.02e-1)" "unprognostic (5.91e-3)" "prognostic unfavorable (3.40e-4)" "unprognostic (1.10e-1)" "unprognostic (9.05e-3)" "unprognostic (1.64e-1)" "unprognostic (3.33e-2)" "unprognostic (1.24e-2)" 15.4 23.2 42.5 16.3 44.2 22.4 13.1 48.4 50.0 30.9 167.1 24.4 10.8 21.6 10.4 44.5 16.1 17.9 47.2 45.5 43.6 41.6 7.9 15.6 13.1 44.0 39.5 23.4 13.0 24.0 41.7 17.2 44.7 27.8 22.1 126.2 18.4 13.7 117.5 24.1 23.2 16.1 34.0 37.1 82.3 16.5 46.3 15.3 13.8 40.3 11.8 34.8 35.2 43.2 21.5 11.5 25.9 30.8 25.7 28.3 40.0 16.8 13.3 14.8 16.2 17.9 15.8 22.5 38.6 16.2 22.6 83.3 32.1 18.6 19.3 24.4 31.1 48.1 32.5 18.0 10.3 14.8 36.5 45.6 18.3 15.9 10.6 30.3 17.8 65.6 45.6 30.8 25.7 56.7 40.7 17.1 26.7 38.4 21.7 28.1 8.7 13.4 54.4 136.4 46.6 27.8 17.1 93.5 29.3 33.3 56.6 4.9 20.4 17.4 16.6 22.3 23.8 11.7 24.3 21.1 12.5 29.2 17.9 11.7 4.6 8.3 6.9 2.2 4.4 3.1 3.8 3.1 3.6 4.5 4.3 6.0 16.4 5.6 4.2 1.3 5.7 4.5 42.5 44.2 48.4 50.0 45.5 43.6 44.0 39.5 44.7 34.0 46.3 43.2 8.3 9.6 5.3 39.2 6.4 8.9 14.4 18.3 35.3 39.1 10.5 11.3 37.2 2.8 37.2 44.1 196.0 3.2 7.7 23.3 7.9 5.7 6.0 10.4 18.0 9.5 59.3 21.2 101.3 4.5 5.0 12.5 91.3 20.8 5.1 31.0 6.8 3.3 49.7 33.7 122.8 6.4 20.3 32.7 6.5 3.5 8.1 29.3 12.4 32.8 8.3 13.8 9.2 82.4 62.7 7.9 20.2 7.9 7.5 9.3 5.1 4.8 44.9 121.1 0.0 27.4 15.4 6.8 18.8 41.3 12.1 4.5 8.6 14.9 7.5 61.5 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 88.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 106.7;Extravillous trophoblasts: 81.7;Hofbauer cells: 137.4;Microglial cells: 185.5;Proximal enterocytes: 216.6" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 43.5;BEWO: 75.8;MCF7: 26.2;OE19: 58.6;RPMI-8226: 38.9;SuSa: 26.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" 2.3 4.0 30.8 1.0 29.1 2.3 4.0 30.0 33.1 22.1 17.4 15.7 48.2 23.1 6.8 2.3 9.8 5.1 2.9 25.4 32.3 3.5 36.0 5.1 1.2 40.1 31.3 8.3 0.8 4.4 8.9 11.7 40.1 7.1 13.9 2.5 5.0 33.8 0.3 0.6 88.3 19.8 31.1 1.4 1.9 3.0 40.0 1.3 6.4 0.9 2.0 2.3 4.0 31.9 1.7 43.5 11.9 0.0 0.4 0.0 75.8 1.9 1.3 2.1 3.5 9.8 0.5 0.0 0.4 0.3 5.4 13.2 0.4 1.2 3.1 13.2 1.9 0.6 0.3 13.0 0.0 0.6 0.1 0.2 5.1 4.8 0.3 1.2 4.1 1.0 1.1 0.0 1.3 26.2 6.3 0.2 4.1 58.6 0.0 3.2 0.0 38.9 0.1 9.5 0.2 0.5 8.9 0.9 1.2 26.1 0.3 0.1 0.0 1.7 1.6 0.4 0.2 11.9 4.7 0.0 3.1 0.0 1.8 0.0 0.0 0.0 0.7 0.0 2.2 0.0 0.2 0.2 0.0 0.5 0.2 0.1 0.0 1.1 0.1 0.2 0.8 0.2 30.8 29.1 30.0 33.1 25.4 32.3 40.1 31.3 40.1 31.1 40.0 31.9 9.4 3.2 1.1 3.9 0.9 3.8 0.3 0.0 0.0 0.4 24.3 1.9 1.6 1.5 0.2 0.0 0.0 16.8 0.6 106.7 1.9 0.0 3.3 0.4 3.8 45.8 3.0 20.6 1.1 0.2 81.7 2.4 0.5 0.5 5.7 0.2 31.4 23.4 137.4 0.0 0.7 12.0 0.0 1.3 2.5 1.2 1.2 2.8 5.4 185.5 0.1 0.7 2.1 11.1 0.9 0.1 44.3 0.4 2.0 0.2 216.6 7.6 0.8 0.9 0.0 0.4 4.3 1.0 4.3 1.1 0.4 37.6 1.0 4.3 6.1 0.2 ABHD3 LABH3 ENSG00000158201 "Abhydrolase domain containing 3, phospholipase" Q8WU67 18 21650901-21704780 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Phospholipid metabolism" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 187.7;Paneth cells: 126.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "REH: 209.6;RPMI-8226: 233.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010729 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA010729: AB_1844449" "unprognostic (1.46e-1)" "unprognostic (4.61e-2)" "unprognostic (2.37e-2)" "unprognostic (3.52e-1)" "unprognostic (8.46e-2)" "unprognostic (3.14e-3)" "unprognostic (3.54e-3)" "unprognostic (1.52e-1)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.21e-2)" "unprognostic (1.98e-1)" "unprognostic (6.37e-2)" "unprognostic (1.73e-1)" "unprognostic (2.15e-2)" "unprognostic (1.00e-1)" "unprognostic (3.98e-2)" "unprognostic (4.58e-2)" 17.1 7.3 13.3 25.2 13.8 17.6 15.7 16.8 21.9 12.6 23.2 63.5 44.1 8.1 9.1 18.1 12.0 20.8 7.5 13.2 14.0 14.5 39.3 15.7 29.8 14.2 15.6 12.5 12.3 16.0 11.4 19.8 16.2 11.1 65.7 5.8 14.5 6.2 14.4 6.3 56.3 9.7 13.2 24.0 35.6 6.3 16.2 21.4 22.9 7.9 25.8 15.3 12.8 15.9 29.0 20.6 19.8 12.7 12.3 8.2 0.1 18.6 7.6 13.1 17.6 21.6 29.1 82.3 33.2 6.2 58.6 93.6 32.5 15.3 18.1 52.1 21.9 9.0 35.7 37.5 18.7 39.6 28.9 7.3 17.7 19.2 8.8 6.5 8.7 28.0 23.4 47.9 11.6 11.7 38.5 43.6 9.7 92.1 47.8 209.6 15.0 233.5 36.4 27.6 16.6 7.5 42.5 37.6 11.2 21.3 11.7 68.9 6.9 12.7 18.2 22.6 29.3 53.1 37.5 84.9 16.1 50.9 29.4 89.3 24.7 29.3 25.3 44.4 19.8 16.2 22.7 24.8 15.2 12.6 18.2 23.2 81.6 18.6 61.8 10.2 44.9 24.3 13.3 13.8 16.8 21.9 13.2 14.0 14.2 15.6 16.2 13.2 16.2 15.9 8.4 9.6 9.3 42.4 22.8 33.4 40.8 21.6 18.2 14.3 12.9 6.2 4.6 40.0 25.4 3.7 47.9 30.6 24.4 187.7 1.9 52.9 4.1 32.6 9.9 9.5 36.4 10.3 27.2 27.5 22.7 10.6 32.1 49.4 11.4 1.2 10.4 31.6 68.5 0.0 30.9 57.9 52.9 31.9 47.2 1.5 7.5 26.4 32.0 33.7 29.6 7.8 26.8 17.1 10.7 51.1 126.6 6.4 45.5 32.0 93.8 8.8 40.8 15.7 13.1 6.8 13.2 4.1 9.7 22.4 15.2 94.3 38.3 5.4 36.8 36.8 ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 278.2;Suprabasal keratinocytes: 270.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "CAB008375: AB_592744, HPA068407: AB_2685983" "unprognostic (2.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (2.51e-2)" "unprognostic (9.24e-3)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (6.04e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-2)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" 28.9 16.2 28.5 35.0 29.2 83.8 29.8 28.3 38.9 30.4 20.9 32.0 32.4 23.6 19.2 53.0 23.8 24.9 16.3 37.4 28.8 27.6 24.9 28.1 48.1 24.7 26.8 26.6 19.9 20.1 12.9 28.3 25.4 20.8 33.0 18.9 32.9 19.1 20.0 42.9 34.1 23.8 26.2 32.3 31.8 14.2 28.0 44.5 22.6 19.6 53.7 34.7 36.5 27.1 55.0 28.6 21.1 21.9 34.4 39.5 34.1 50.9 31.2 35.0 37.5 33.7 61.7 101.1 23.2 51.7 23.0 57.7 28.0 37.0 41.0 65.2 24.2 44.5 18.0 29.0 23.6 23.2 43.9 28.1 54.6 35.3 21.8 41.5 43.7 33.5 30.7 67.2 40.5 25.4 49.8 26.0 18.8 37.5 13.5 51.4 41.2 69.2 48.0 22.9 17.1 18.5 41.3 44.5 46.8 29.4 27.7 35.5 50.6 27.3 33.2 34.4 25.5 15.0 24.0 108.7 38.7 61.1 17.4 77.3 35.5 91.4 42.1 43.2 40.8 57.2 40.9 48.5 39.4 47.7 37.7 41.7 64.3 35.8 45.4 34.1 76.5 57.2 28.5 29.2 28.3 38.9 37.4 28.8 24.7 26.8 25.4 26.2 28.0 27.1 44.4 41.7 37.7 278.2 89.3 246.2 127.9 74.0 123.5 9.6 40.5 26.5 23.2 38.6 73.5 25.8 2.1 36.4 75.7 69.7 13.7 56.3 11.3 72.1 41.3 41.9 44.9 43.8 81.6 52.1 46.9 45.9 42.3 111.5 57.7 22.3 32.9 25.6 75.8 16.8 133.7 54.9 83.4 80.5 116.3 5.7 22.1 92.1 92.5 106.8 89.8 48.2 73.2 128.7 47.4 82.2 52.1 22.2 56.8 132.5 52.7 39.0 86.2 10.0 32.9 29.8 40.3 14.7 10.8 109.6 270.6 77.2 71.0 27.2 41.3 195.4 ABITRAM "C9orf6, CG-8, FAM206A, FLJ20457, Simiate" ENSG00000119328 "Actin binding transcription modulator" Q9NX38 9 108934400-108950744 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 20.7;Cytotrophoblasts: 6.0;Extravillous trophoblasts: 10.6;Fibroblasts: 4.3;Hofbauer cells: 7.8;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035917, HPA035918" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA No "Cluster 31: Non-specific - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA035917: AB_2674860, HPA035918: AB_10670593" "unprognostic (4.89e-2)" "unprognostic (2.62e-1)" "unprognostic (1.85e-1)" "unprognostic (4.00e-3)" "unprognostic (1.05e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-3)" "unprognostic (1.10e-2)" "unprognostic (1.83e-2)" "unprognostic (1.42e-1)" "unprognostic (1.16e-2)" "unprognostic (3.50e-2)" "unprognostic (1.57e-2)" "unprognostic (3.25e-2)" "unprognostic (2.03e-1)" "unprognostic (2.28e-1)" "unprognostic (1.62e-1)" 14.2 11.9 17.2 10.0 18.7 15.6 17.2 16.8 21.9 12.5 18.7 14.9 14.4 13.6 25.1 16.4 21.5 10.9 15.8 17.7 17.3 13.6 14.6 12.7 9.0 16.8 17.1 13.5 13.3 23.2 13.9 12.5 17.2 12.1 16.2 24.7 15.3 14.2 13.2 24.5 13.1 12.5 17.5 8.5 14.5 20.2 17.5 11.9 19.0 11.8 12.0 11.9 11.4 18.3 18.5 19.8 19.5 23.4 36.2 44.6 28.1 17.1 20.0 17.0 13.9 29.5 9.7 17.0 9.8 16.6 22.3 41.3 17.2 18.3 16.0 10.4 17.6 10.5 25.8 27.0 30.7 40.4 13.3 25.3 33.6 20.7 47.6 20.9 23.7 26.1 39.7 16.6 20.3 53.0 28.9 16.3 22.6 55.9 28.7 13.9 33.9 18.9 22.5 19.2 26.7 13.7 27.0 23.3 30.1 20.0 31.6 21.4 14.9 9.2 16.9 39.3 21.7 14.7 38.5 12.6 30.1 15.6 13.4 38.8 31.2 31.0 14.8 33.4 22.6 16.5 23.1 19.6 35.5 10.8 22.9 17.6 37.4 21.1 34.6 37.0 21.1 20.1 17.2 18.7 16.8 21.9 17.7 17.3 16.8 17.1 17.2 17.5 17.5 18.3 2.9 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 0.0 0.0 0.0 0.0 6.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 10.6 4.3 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 7.3 0.3 0.0 0.0 0.0 ABLIM3 KIAA0843 ENSG00000173210 "Actin binding LIM protein family member 3" O94929 5 149141483-149260542 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 115.8" "Cell type enhanced" "Detected in many" "Adipocytes: 197.6;Cardiomyocytes: 61.7;Hepatocytes: 116.0;Oligodendrocyte precursor cells: 63.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 75.3;HHSteC: 77.6;HSkMC: 89.4;hTERT-HME1: 90.9;hTERT-RPE1: 76.2;TIME: 103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003245 Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 30000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Cell Junctions" "HPA003245: AB_1078083" "unprognostic (1.07e-1)" "unprognostic (1.31e-1)" "unprognostic (9.87e-2)" "unprognostic (1.75e-1)" "unprognostic (8.74e-2)" "unprognostic (4.19e-2)" "unprognostic (9.48e-3)" "unprognostic (4.37e-3)" "unprognostic (1.05e-1)" "unprognostic (1.09e-2)" "unprognostic (4.17e-3)" "unprognostic (2.42e-1)" "prognostic unfavorable (1.28e-4)" "unprognostic (3.12e-2)" "unprognostic (8.10e-2)" "unprognostic (2.45e-3)" "unprognostic (1.20e-1)" 68.4 7.4 19.2 3.8 18.0 0.5 57.6 49.7 19.1 12.5 6.8 11.1 2.7 10.4 6.3 33.2 14.4 7.1 87.8 20.4 26.7 19.8 115.8 20.0 5.3 37.2 25.2 3.9 2.7 59.6 6.8 34.4 28.7 9.1 5.0 28.6 6.5 8.2 45.8 8.3 7.8 10.6 34.0 8.7 5.4 2.0 29.9 2.2 9.2 38.7 4.5 14.1 17.7 30.2 23.6 4.8 0.0 0.2 39.6 75.3 0.1 16.1 44.8 9.1 15.8 0.1 16.2 0.0 2.7 20.5 47.9 0.5 0.1 18.9 17.7 0.1 0.2 0.0 1.4 0.6 77.6 0.0 0.1 89.4 5.1 32.5 90.9 76.2 41.1 0.0 0.0 7.2 54.8 9.2 0.0 0.0 0.2 1.5 63.0 0.0 0.1 0.0 50.3 16.0 6.3 0.1 3.3 1.1 8.7 1.2 1.5 0.1 103.9 18.9 4.2 19.9 27.7 0.1 0.0 0.0 33.5 0.0 55.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.2 0.0 2.7 19.2 18.0 49.7 19.1 20.4 26.7 37.2 25.2 28.7 34.0 29.9 30.2 197.6 0.0 3.7 21.5 1.3 1.5 1.2 2.6 0.6 2.5 7.6 3.9 61.7 18.6 5.3 0.0 0.0 0.2 0.3 0.0 5.9 8.7 3.0 0.5 2.5 39.6 0.0 0.0 31.0 3.5 0.7 9.4 3.6 2.5 1.3 0.0 34.2 116.0 12.3 28.6 33.7 0.0 8.2 13.5 1.1 0.5 0.3 8.5 5.4 21.5 0.9 19.3 0.0 63.8 25.6 22.5 0.0 0.7 0.1 2.5 0.0 23.5 4.9 25.1 0.0 7.4 7.7 1.7 2.7 2.0 1.6 0.4 0.7 0.5 0.0 22.2 AC004691.2 ENSG00000250424 "Novel protein, MINDY4 and AQP1 readthrough" 7 30852273-30923812 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019206, HPA030130" Approved Approved "Plasma membrane" NA NA "Plasma membrane" "HPA019206: AB_1844965, HPA030130: AB_10601565" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" "unprognostic (2.72e-4)" "unprognostic (5.13e-2)" "unprognostic (3.44e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-2)" "unprognostic (3.76e-1)" "unprognostic (2.49e-1)" "unprognostic (3.71e-2)" 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.3 0.3 0.0 0.5 0.4 0.4 0.4 0.2 0.6 0.9 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC004922.1 ENSG00000284292 "Novel protein, ARPC1A and ARPC1B readthrough" 7 99325879-99394653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Club cells: 2.5;Exocrine glandular cells: 1.5;granulocytes: 1.3;Pancreatic endocrine cells: 1.1" "Not detected" "Not detected" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004334 Uncertain Approved "Cell Junctions,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" Cytosol "HPA004334: AB_1078215" 1.5 1.2 0.1 0.9 0.1 0.5 1.2 0.1 0.3 1.1 0.0 1.4 0.9 0.9 0.0 1.3 1.0 0.1 1.0 0.2 0.1 1.0 1.2 1.8 0.8 0.5 0.2 0.8 0.9 0.1 0.8 0.2 0.3 0.9 0.0 0.0 1.2 0.0 0.4 0.7 1.9 0.2 0.1 2.9 1.2 0.5 0.2 0.2 1.2 0.0 0.1 1.2 1.0 0.0 1.9 2.1 0.4 0.2 0.3 1.0 2.5 1.6 0.7 0.9 1.0 4.1 3.5 2.5 4.8 1.5 1.7 1.6 0.1 1.1 0.2 1.0 1.7 1.2 1.3 0.9 0.2 1.4 1.4 1.4 0.7 1.3 0.6 0.3 1.0 0.8 1.6 2.2 1.0 5.1 3.8 0.1 0.7 0.7 2.8 1.4 0.3 0.7 0.2 1.0 0.4 0.3 1.3 2.7 6.0 0.3 0.8 0.7 2.0 3.3 1.3 3.6 2.4 0.0 1.0 2.4 1.7 2.5 3.5 11.8 20.7 23.7 8.7 20.4 6.2 9.3 8.5 8.7 16.6 11.1 7.1 6.9 16.9 7.1 18.7 11.2 16.5 31.5 0.1 0.1 0.1 0.3 0.2 0.1 0.5 0.2 0.3 0.1 0.2 0.0 0.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.3 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.5 0.5 0.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 1.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 AC005324.2 ENSG00000251537 "Novel tripartite motif-containing 16 (TRIM16) and CMT1A duplicated region transcript 1 (CDRT1) protein" 17 15571491-15651653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;CAPAN-2: 1.1;HaCaT: 2.1;HeLa: 1.1" "HPA023623, HPA066431" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (3.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (2.48e-1)" "unprognostic (1.24e-2)" "unprognostic (3.52e-2)" "unprognostic (2.87e-3)" "unprognostic (1.93e-1)" "unprognostic (2.98e-2)" "unprognostic (4.39e-2)" "unprognostic (4.81e-3)" "unprognostic (6.35e-3)" "unprognostic (1.80e-11)" "unprognostic (1.95e-1)" "unprognostic (1.36e-1)" "unprognostic (5.30e-2)" "unprognostic (3.09e-1)" 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC005726.1 ENSG00000258472 "Novel protein" 17 28455752-28614185 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Alveolar cells type 2: 13.2;Club cells: 5.6;granulocytes: 6.3;Proximal tubular cells: 20.4;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.0" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 2: Karpas-707 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.26e-2)" "unprognostic (1.82e-1)" "unprognostic (6.04e-3)" "unprognostic (1.19e-1)" "unprognostic (1.14e-1)" "unprognostic (2.23e-3)" "unprognostic (2.76e-3)" "unprognostic (7.25e-2)" "unprognostic (5.96e-2)" "unprognostic (4.58e-2)" "unprognostic (9.22e-3)" "unprognostic (3.17e-3)" "unprognostic (1.49e-4)" "unprognostic (1.25e-1)" "unprognostic (2.65e-1)" "unprognostic (7.50e-2)" "unprognostic (3.79e-4)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 9.6 13.2 0.0 0.6 0.0 0.0 0.0 0.0 0.0 2.3 2.4 0.0 0.0 5.6 3.7 0.0 1.7 0.5 0.0 1.9 1.2 0.0 1.7 2.4 1.4 0.0 0.0 0.0 2.0 0.8 1.6 0.0 3.2 6.3 2.6 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 20.4 5.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 5.3 1.1 1.2 0.0 0.0 AC008403.1 ENSG00000268465 "Novel protein" 19 48465837-48472431 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.2;retina: 5.2;testis: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;LHCN-M2: 1.4;NB-4: 1.5;U-698: 2.2" HPA060662 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Plasma membrane, Cytosol" "HPA060662: AB_2732652" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.1 0.0 1.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 5.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.1 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.9 0.5 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.4 0.0 0.0 1.5 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.3 0.3 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC020907.6 ENSG00000285526 "Novel protein" 19 35106510-35124297 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.3;choroid plexus: 3.1;salivary gland: 7.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 3.9;Club cells: 1.3;Respiratory ciliated cells: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SCLC-21H: 6.2;WM-115: 8.9" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 3.8" HPA010856 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" 0.0 0.0 2.4 0.0 3.1 0.0 0.4 2.7 3.2 1.4 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 2.4 0.0 0.1 0.0 0.0 2.9 2.7 0.0 1.8 0.0 0.2 2.6 0.3 0.0 0.2 7.3 0.1 0.0 1.6 0.0 0.0 2.3 0.0 0.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.1 2.7 3.2 2.2 2.4 2.9 2.7 2.6 2.3 2.6 3.3 0.0 6.4 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC127029.3 ENSG00000285947 "Novel protein" 17 63917203-63931385 "Predicted membrane proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "memory B-cell: 14.0;naive B-cell: 18.4" "Lineage enriched" "Detected in many" 5 "B-cells: 18.4" "Cell line enhanced" "Detected in single" "U-698: 2.2" "HPA009178, HPA043715" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA009178: AB_1078483, HPA043715: AB_2678632" 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.2 0.0 0.0 0.0 0.1 0.1 0.0 0.5 2.2 0.4 14.0 0.7 0.3 0.5 18.4 0.4 0.2 0.0 0.5 3.8 0.0 1.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC138696.1 ENSG00000264668 "Novel protein" 8 143247110-143276403 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 1.7;MOLT-4: 1.2" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (2.24e-2)" "unprognostic (2.10e-1)" "unprognostic (3.56e-3)" "unprognostic (1.87e-1)" "unprognostic (8.68e-3)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (9.80e-2)" "unprognostic (4.20e-1)" "unprognostic (3.27e-2)" "unprognostic (1.34e-1)" "unprognostic (1.03e-2)" "unprognostic (2.20e-2)" "unprognostic (3.99e-1)" "unprognostic (2.59e-2)" "unprognostic (4.06e-1)" 0.3 0.3 0.2 0.0 0.3 0.0 0.2 0.1 0.5 0.3 0.0 0.4 0.1 0.6 0.0 0.1 0.7 0.0 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.2 0.4 0.4 0.6 0.1 0.2 0.0 0.3 0.3 0.0 0.1 0.2 0.2 0.4 0.1 0.3 0.2 0.2 0.1 0.3 0.2 0.3 0.0 0.1 0.0 0.0 0.4 0.1 0.2 0.5 0.0 0.0 0.3 1.7 0.1 0.1 0.5 1.1 0.6 0.2 0.0 0.7 0.0 0.3 0.1 0.1 0.2 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.1 0.2 1.0 0.4 0.0 0.3 0.2 0.3 0.4 0.0 0.0 0.0 0.0 1.2 0.0 1.1 0.1 0.3 0.6 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.3 0.3 0.0 0.0 0.2 1.1 0.0 0.8 0.2 0.5 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.3 0.1 0.5 0.3 0.3 0.2 0.4 0.3 0.2 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACIN1 "ACINUS, fSAP152, KIAA0670" ENSG00000100813 "Apoptotic chromatin condensation inducer 1" Q9UKV3 14 23058564-23095614 "Plasma proteins, Predicted intracellular proteins, Transporters" "Apoptosis, mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000657 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 30000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 60: Granulocytes - Receptor signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA000657: AB_1078091" "unprognostic (2.54e-3)" "unprognostic (1.99e-1)" "unprognostic (1.38e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.89e-3)" "prognostic unfavorable (4.88e-5)" "unprognostic (1.49e-3)" "unprognostic (9.70e-2)" "unprognostic (4.11e-2)" "unprognostic (1.00e-2)" "unprognostic (6.64e-3)" "unprognostic (1.35e-3)" "unprognostic (4.34e-2)" "unprognostic (2.78e-2)" "unprognostic (2.28e-2)" "unprognostic (7.33e-2)" 41.5 57.7 58.3 35.0 60.2 66.7 36.6 64.3 64.6 46.1 62.7 42.6 28.6 41.5 30.1 50.9 39.3 24.3 44.1 57.5 63.4 51.3 47.5 33.8 45.2 60.9 60.6 48.7 45.1 41.4 48.5 37.2 59.9 45.8 33.2 39.0 39.1 27.8 53.0 39.5 46.0 38.9 55.7 66.4 45.3 47.6 61.6 52.8 47.1 36.5 47.4 41.9 41.3 64.4 77.1 77.6 120.0 97.7 73.3 58.5 120.2 83.8 58.8 98.9 80.0 103.8 87.8 141.8 48.4 69.7 65.0 82.6 167.4 95.6 100.7 100.2 74.3 124.5 82.9 144.8 41.8 136.6 106.4 69.0 58.0 101.5 84.8 81.0 87.9 103.4 117.2 55.1 75.7 96.5 156.1 134.6 135.1 84.6 73.3 139.7 93.0 75.8 82.9 133.3 79.7 58.6 111.2 71.7 69.1 86.7 59.2 109.0 90.7 67.3 67.3 64.7 78.5 57.9 70.2 144.0 59.9 101.8 74.8 5.3 4.0 5.1 4.2 3.5 3.2 3.8 2.9 3.2 3.4 5.4 3.8 3.7 10.8 7.5 3.2 5.5 3.5 2.6 58.3 60.2 64.3 64.6 57.5 63.4 60.9 60.6 59.9 55.7 61.6 64.4 49.8 70.5 123.0 44.4 61.6 37.3 30.2 52.7 64.9 38.1 43.4 40.8 67.9 32.9 67.2 35.0 27.1 58.0 65.0 64.4 17.6 53.4 42.5 70.5 97.6 55.5 58.3 76.2 41.0 49.3 66.8 60.3 85.1 90.1 130.6 79.4 35.0 28.8 47.1 15.2 43.6 50.1 42.7 38.1 40.8 10.9 46.0 52.5 26.6 44.0 53.4 26.1 54.6 45.8 65.6 59.4 49.7 38.4 65.4 43.5 37.7 21.6 82.6 43.3 6.6 52.4 66.9 42.1 39.2 58.5 46.5 69.2 65.2 86.1 55.8 38.4 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACOT13 "HT012, THEM2" ENSG00000112304 "Acyl-CoA thioesterase 13" Q9NPJ3 6 24667035-24705065 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 30.6" "Cell type enhanced" "Detected in all" "Early spermatids: 847.1;Proximal tubular cells: 525.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019881, HPA057134" Enhanced Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "HPA019881: AB_1857978, HPA057134: " "unprognostic (3.61e-1)" "unprognostic (1.62e-1)" "unprognostic (6.02e-2)" "unprognostic (1.80e-2)" "unprognostic (9.57e-2)" "unprognostic (1.21e-1)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.71e-1)" "prognostic favorable (2.53e-6)" "unprognostic (3.67e-2)" "unprognostic (1.64e-2)" "unprognostic (7.16e-2)" "unprognostic (5.97e-2)" "unprognostic (4.86e-2)" "unprognostic (1.50e-1)" "unprognostic (2.13e-2)" 6.3 6.1 7.2 4.8 7.5 3.4 3.8 7.9 7.3 3.4 6.0 9.1 6.5 3.1 3.7 3.4 3.6 4.9 12.0 6.6 7.8 19.2 30.6 4.6 5.2 7.2 7.8 3.9 6.6 7.2 5.1 3.0 7.4 6.5 7.4 9.6 5.0 3.3 12.2 5.5 6.1 3.1 7.1 4.8 5.5 7.0 8.2 5.1 5.7 10.3 3.4 3.5 3.1 7.4 5.9 7.6 7.6 13.6 10.5 13.1 4.2 4.8 5.8 3.5 5.4 10.1 7.5 11.1 16.2 5.5 18.4 6.4 6.7 9.7 5.4 17.4 6.2 10.4 7.7 7.0 5.3 6.7 4.6 7.6 9.4 4.7 9.0 8.5 8.3 11.3 17.0 5.7 7.0 6.1 12.1 12.9 5.1 11.7 5.9 10.4 6.6 14.0 11.7 5.4 15.0 5.2 5.7 19.1 14.1 8.8 13.2 5.5 9.7 6.2 3.5 1.7 4.6 10.7 29.3 11.1 6.5 23.8 19.1 4.8 5.3 3.6 4.4 5.7 6.1 6.9 4.9 5.0 4.7 4.9 5.7 5.1 6.2 4.6 5.8 3.7 5.3 4.8 7.2 7.5 7.9 7.3 6.6 7.8 7.2 7.8 7.4 7.1 8.2 7.4 27.9 67.3 41.7 19.6 19.7 17.2 26.6 66.4 18.8 18.7 29.4 32.3 94.6 45.8 46.9 31.3 16.7 56.8 22.6 88.4 158.5 43.2 847.1 34.0 31.3 24.0 54.7 37.2 12.1 40.2 31.1 26.2 23.9 31.8 14.5 30.3 21.4 215.5 86.7 5.0 14.3 85.8 67.1 24.5 23.7 131.5 19.6 35.0 26.6 14.0 68.9 41.7 18.6 15.6 18.7 29.2 130.7 24.0 25.4 23.2 47.1 525.2 56.8 31.8 26.3 50.6 64.2 117.1 27.3 19.5 23.4 40.0 20.5 43.4 69.4 28.6 ACOT9 "ACATE2, CGI-16, MT-ACT48" ENSG00000123130 "Acyl-CoA thioesterase 9" Q9Y305 X 23701055-23766475 "Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Serine esterase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035533 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 7600 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA035533: AB_10696506" "unprognostic (5.69e-2)" "unprognostic (6.34e-2)" "unprognostic (1.59e-1)" "unprognostic (2.09e-1)" "unprognostic (1.53e-2)" "unprognostic (1.27e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (1.12e-1)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (9.75e-3)" "unprognostic (3.49e-2)" "unprognostic (2.15e-3)" "unprognostic (6.53e-2)" "unprognostic (1.68e-1)" "unprognostic (1.44e-1)" "unprognostic (1.14e-1)" 24.1 18.8 8.0 19.5 7.5 15.8 19.8 7.5 9.5 17.7 10.3 22.0 15.5 22.5 8.4 12.1 17.3 13.6 49.3 7.2 9.1 15.5 14.5 26.1 12.7 8.0 7.5 15.1 14.0 11.7 8.8 17.8 8.6 16.1 16.4 9.6 18.6 22.1 27.6 12.5 15.8 32.3 6.9 18.4 17.7 6.2 8.5 6.3 17.4 14.2 12.5 21.3 14.7 7.5 81.5 54.0 23.1 51.4 37.2 42.0 11.7 62.7 54.3 60.7 58.4 48.5 71.4 4.1 39.1 70.5 81.8 48.3 29.6 79.9 84.2 18.8 44.6 27.4 55.0 35.6 49.9 10.8 33.3 37.5 53.6 71.5 80.5 39.6 90.3 0.6 17.7 26.7 66.7 28.4 15.2 26.1 33.9 31.8 65.3 15.7 87.6 34.4 72.8 29.8 4.5 22.1 68.4 28.3 41.6 85.5 31.9 14.0 84.7 50.7 33.8 73.3 34.7 6.4 16.1 0.5 37.4 10.5 43.6 24.7 30.2 22.2 10.2 43.5 14.1 11.1 12.6 11.3 32.4 9.9 4.0 9.4 15.8 12.3 56.2 5.4 20.8 18.6 8.0 7.5 7.5 9.5 7.2 9.1 8.0 7.5 8.6 6.9 8.5 7.5 34.6 48.1 27.3 12.1 23.0 20.1 45.9 51.8 7.4 5.3 5.6 6.7 44.3 18.6 36.8 16.5 25.0 4.0 21.5 9.7 5.9 59.6 0.8 20.8 22.9 38.7 2.4 11.2 6.1 52.5 11.4 33.4 16.8 21.6 37.3 14.8 32.9 11.8 42.4 5.0 8.6 10.3 16.2 37.1 95.4 0.4 18.0 57.3 33.8 13.1 192.3 11.9 19.6 4.5 3.1 83.4 15.0 25.6 27.7 52.4 14.6 30.3 38.0 9.9 26.3 35.2 65.1 1.6 10.4 3.5 10.7 3.0 21.2 30.4 11.2 38.2 ACTN1 ENSG00000072110 "Actinin alpha 1" P12814 14 68874128-68979440 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "smooth muscle: 524.5" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 351.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 364.2" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004303, HPA006035" Approved Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 210000000 "Cluster 5: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB004303: AB_626633, HPA006035: AB_1078095" "unprognostic (4.40e-2)" "unprognostic (1.03e-3)" "unprognostic (2.49e-2)" "unprognostic (1.96e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.49e-4)" "unprognostic (6.19e-3)" "prognostic unfavorable (7.63e-5)" "unprognostic (3.62e-1)" "unprognostic (3.23e-2)" "unprognostic (3.16e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (9.08e-10)" "unprognostic (2.87e-2)" "unprognostic (2.00e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (8.00e-4)" 117.4 40.7 27.3 149.5 55.8 149.3 103.5 0.1 32.0 118.4 20.1 449.8 49.8 313.1 60.3 154.4 152.1 143.9 121.4 29.7 14.7 46.7 61.8 100.0 47.5 24.5 11.0 61.8 46.8 9.1 27.3 96.1 7.3 174.3 109.0 28.2 116.4 295.1 21.7 59.3 106.9 524.5 4.2 55.9 171.7 21.2 32.9 32.6 35.0 13.3 50.7 305.9 83.3 28.8 871.9 262.3 158.6 121.4 275.2 180.5 592.4 749.3 712.0 770.0 571.1 211.8 196.6 0.7 256.5 744.7 310.4 370.9 126.8 790.3 965.2 4.6 38.5 118.2 133.5 179.0 494.0 85.4 14.3 231.7 152.1 479.8 540.3 551.6 428.6 48.2 56.9 1.4 612.0 246.9 10.1 181.1 124.7 217.9 198.1 59.3 294.1 32.6 292.0 225.6 57.0 68.7 649.9 96.8 177.1 474.8 146.0 170.9 546.0 1085.2 432.8 126.9 662.5 113.8 47.8 3.9 314.4 115.7 584.4 64.6 67.5 137.1 5.7 28.8 7.1 0.1 22.7 12.4 45.5 0.2 103.9 92.2 364.2 4.5 8.9 2.0 9.6 89.2 27.3 55.8 0.1 32.0 29.7 14.7 24.5 11.0 7.3 4.2 32.9 28.8 44.7 38.5 25.1 19.6 4.0 119.3 154.9 137.4 82.0 74.7 88.6 157.6 60.3 51.5 36.0 42.3 246.0 155.3 3.0 17.2 3.9 186.8 34.0 65.8 112.8 135.5 38.5 21.9 102.7 144.9 351.8 88.9 34.1 90.2 7.6 15.9 129.5 96.6 79.5 18.5 29.7 57.3 59.0 100.9 82.1 10.7 35.8 96.4 30.2 34.7 105.1 6.0 4.1 9.0 4.3 203.7 28.0 245.6 0.6 132.6 2.4 15.3 47.8 80.8 177.5 30.0 270.6 19.4 18.4 51.8 59.8 66.9 22.7 20.9 47.0 67.1 ACTR10 "ACTR11, Arp10, Arp11, HARP11" ENSG00000131966 "Actin related protein 10" Q9NZ32 14 58200080-58235636 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000699 Approved "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane, Focal adhesion sites" "HPA000699: " "prognostic unfavorable (3.24e-4)" "unprognostic (4.61e-2)" "unprognostic (6.22e-3)" "unprognostic (2.03e-2)" "unprognostic (4.42e-1)" "unprognostic (1.36e-2)" "prognostic unfavorable (2.71e-5)" "unprognostic (3.20e-1)" "unprognostic (9.30e-2)" "unprognostic (1.53e-1)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.48e-8)" "unprognostic (1.01e-2)" "unprognostic (2.39e-1)" "unprognostic (2.43e-2)" "unprognostic (8.48e-2)" 12.6 18.0 22.4 3.1 22.4 5.4 12.5 23.4 41.5 15.9 24.5 13.5 2.7 10.2 5.0 16.4 12.7 4.2 22.9 22.2 22.9 18.0 18.5 10.8 4.2 22.3 22.4 15.8 17.4 8.7 20.3 6.4 22.5 14.5 4.4 5.5 10.3 4.7 10.2 13.2 11.3 6.1 22.1 14.7 13.2 10.8 23.0 5.3 13.6 4.1 4.3 12.0 13.9 22.9 4.1 2.6 4.6 1.8 15.3 7.3 2.3 3.1 3.6 4.9 6.1 3.5 4.8 6.3 4.5 6.7 3.0 4.2 6.2 4.5 7.2 3.3 15.3 2.4 4.6 6.9 13.0 4.3 3.4 9.7 6.8 4.5 8.5 4.3 6.7 3.6 2.1 5.0 10.3 11.3 5.7 16.2 2.3 4.0 20.8 4.0 8.0 3.7 9.1 5.2 2.6 2.9 5.9 4.9 16.9 5.2 8.4 7.1 5.4 5.3 11.3 4.9 2.8 2.9 2.0 7.1 5.8 3.3 3.2 15.7 5.4 8.6 6.2 7.3 9.2 6.1 7.0 6.2 4.3 4.1 7.2 7.5 7.8 5.9 8.5 4.8 5.5 4.0 22.4 22.4 23.4 41.5 22.2 22.9 22.3 22.4 22.5 22.1 23.0 22.9 68.3 60.9 44.2 28.7 39.9 53.3 66.4 125.7 34.1 71.4 35.8 43.3 77.0 42.9 75.1 51.5 29.2 110.1 46.4 59.6 125.2 81.2 8.7 40.3 46.7 54.4 33.6 60.0 48.6 59.6 76.9 73.4 32.1 29.7 43.7 49.6 47.8 31.8 77.8 57.2 47.3 48.1 105.8 32.0 38.4 11.6 88.3 47.2 74.7 23.4 52.8 101.4 35.0 40.2 54.6 75.0 29.1 80.1 34.7 59.1 56.3 111.7 67.7 72.0 78.9 54.5 96.6 116.4 60.4 45.7 64.4 156.0 46.1 81.3 41.3 54.6 ACTR6 "ARP6, FLJ13433" ENSG00000075089 "Actin related protein 6" Q9GZN1 12 100199122-100241865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038587, HPA038588" Uncertain Approved "Plasma membrane,Cytosol" No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA038587: AB_10670781, HPA038588: AB_10672719" "unprognostic (1.24e-2)" "unprognostic (8.43e-3)" "unprognostic (1.81e-1)" "unprognostic (1.14e-1)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "prognostic unfavorable (7.70e-9)" "unprognostic (4.11e-2)" "unprognostic (1.09e-1)" "unprognostic (1.05e-1)" "unprognostic (6.98e-2)" "unprognostic (3.99e-1)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "unprognostic (3.22e-1)" "unprognostic (6.67e-3)" "unprognostic (3.40e-2)" 15.0 16.7 17.6 12.8 17.7 7.4 28.9 18.2 24.5 13.9 17.9 14.6 15.2 15.2 18.1 13.8 14.2 10.3 17.5 18.2 19.8 22.1 19.6 12.2 20.8 18.0 18.6 17.9 5.0 20.8 4.5 17.0 19.1 16.8 15.3 20.6 15.3 15.9 14.3 13.6 14.4 14.4 18.3 16.1 10.6 21.3 17.7 20.4 16.3 15.8 19.2 17.1 4.5 20.8 60.2 23.5 27.1 35.9 22.4 28.3 63.3 26.0 22.6 25.0 18.2 15.2 17.8 32.9 24.7 19.5 18.8 23.0 36.5 22.5 34.3 48.9 33.8 22.8 22.2 17.7 23.6 33.7 17.7 17.4 27.7 20.2 25.8 38.5 28.9 38.0 36.9 10.5 29.2 15.5 33.7 50.8 31.6 22.5 34.2 27.0 27.3 41.4 27.3 35.8 24.8 47.0 35.3 62.5 36.5 22.4 40.6 39.5 18.8 18.4 12.3 20.5 23.7 23.6 55.6 42.8 12.1 21.2 21.7 5.7 6.4 10.0 15.2 11.5 19.3 12.6 17.9 20.3 8.2 12.1 19.4 19.6 3.0 19.4 13.2 12.0 20.5 12.1 17.6 17.7 18.2 24.5 18.2 19.8 18.0 18.6 19.1 18.3 17.7 20.8 33.5 16.0 17.7 6.5 25.8 22.9 36.2 72.4 29.6 32.7 26.5 23.9 34.8 8.6 38.1 23.9 18.8 55.6 36.9 9.9 46.9 21.4 135.2 56.8 27.7 20.7 12.5 21.7 20.9 12.0 68.4 25.0 12.2 28.9 33.0 19.1 16.1 16.4 23.7 33.7 23.2 11.3 73.2 19.1 13.4 34.3 20.2 17.5 32.0 13.1 19.5 27.0 25.7 17.1 17.4 13.2 10.0 22.6 19.7 24.7 11.7 67.9 67.9 32.8 32.9 27.8 36.8 80.8 19.9 23.8 19.7 96.0 36.6 23.8 13.3 33.8 ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 507.2;lymphoid tissue: 259.0" "Cell type enhanced" "Detected in many" "dendritic cells: 76.4;Extravillous trophoblasts: 128.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 168.5;NK-cell: 94.5;non-classical monocyte: 362.8;plasmacytoid DC: 218.6" "Group enriched" "Detected in all" 4 "dendritic cells: 218.6;monocytes: 362.8;NK-cells: 94.5" "Group enriched" "Detected in many" 5 "JURKAT: 570.9;MOLT-4: 1915.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 16.6 6.3 6.9 18.5 8.2 20.2 10.9 6.8 9.4 7.3 5.6 5.7 507.2 3.8 1.7 9.0 5.6 9.2 17.8 6.9 7.0 3.3 4.4 6.2 33.4 7.2 8.2 2.1 5.3 1.5 1.3 4.6 7.2 4.3 3.6 0.3 4.7 2.8 5.3 6.0 17.9 5.7 6.1 17.5 46.0 2.4 8.7 259.0 5.8 6.4 26.4 9.3 5.4 8.8 14.0 37.7 19.2 13.2 35.6 48.7 30.5 13.7 7.8 13.2 9.3 17.5 14.8 38.4 15.8 17.9 24.7 2.2 13.2 55.1 7.3 2.9 17.2 7.8 6.6 13.5 15.0 6.3 20.3 234.3 23.2 5.1 9.0 12.6 50.3 570.9 20.4 30.7 6.0 33.1 1915.5 28.9 5.2 17.2 13.5 102.3 25.8 95.0 2.3 0.0 0.7 9.3 20.2 4.4 24.2 24.0 4.5 19.1 16.9 10.1 18.6 20.5 2.8 40.1 27.3 82.3 3.5 32.5 9.0 0.5 9.8 1.2 43.3 168.5 27.8 7.5 35.5 51.0 35.2 7.6 27.3 38.6 2.5 94.5 362.8 218.6 29.8 57.4 6.9 8.2 6.8 9.4 6.9 7.0 7.2 8.2 7.2 6.1 8.7 8.8 18.2 0.0 1.9 2.9 13.5 12.9 3.4 10.0 13.6 0.0 2.7 3.2 2.1 0.0 4.8 1.8 0.0 2.9 76.4 0.8 0.0 3.7 0.4 0.7 9.1 17.0 0.0 10.7 0.2 19.7 128.2 19.7 14.8 0.8 0.0 3.5 7.1 3.6 28.5 0.0 0.2 1.5 10.2 20.8 25.5 1.8 42.3 27.6 8.8 3.7 37.4 3.8 56.7 0.5 9.4 10.7 0.3 2.6 31.4 6.0 0.7 3.0 2.4 0.0 13.1 1.9 14.1 0.3 6.2 12.9 13.9 3.7 30.9 6.8 4.9 2.7 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADAM22 MDC2 ENSG00000008277 "ADAM metallopeptidase domain 22" Q9P0K1 7 87934143-88202889 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 77.2" "Group enriched" "Detected in many" 4 "Excitatory neurons: 286.7;Inhibitory neurons: 304.9;Oligodendrocyte precursor cells: 184.0;Oligodendrocytes: 125.6" "Cancer enhanced" "Detected in many" "glioma: 4.0" "Region enhanced" "Detected in all" "cerebellum: 77.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 81.8;SH-SY5Y: 76.9;U-266/84: 33.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050325, CAB079064" Supported Approved "Cell Junctions" "Intracellular and membrane" NA NA 180000 "Cluster 38: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "CAB079064: , HPA050325: AB_2681087" "unprognostic (1.20e-2)" "unprognostic (8.61e-2)" "unprognostic (3.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.89e-2)" "unprognostic (3.09e-1)" "unprognostic (7.84e-3)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-1)" "unprognostic (3.71e-3)" "unprognostic (1.69e-1)" "unprognostic (3.47e-2)" "unprognostic (4.13e-2)" "unprognostic (2.77e-1)" "unprognostic (1.61e-4)" "unprognostic (4.70e-2)" 2.0 9.1 7.2 0.9 9.2 0.9 1.3 77.2 30.6 6.0 0.0 1.5 0.6 4.6 8.5 0.8 2.4 2.5 2.1 12.2 8.9 3.8 0.2 1.2 2.2 14.4 5.6 3.9 1.0 2.1 3.4 0.3 14.7 11.0 1.4 10.3 0.7 5.1 2.5 1.0 1.1 3.5 2.7 2.0 0.6 1.9 13.8 2.5 3.2 1.2 1.1 1.6 2.6 12.3 2.5 0.7 4.8 5.8 1.4 0.3 3.5 0.1 0.5 0.4 0.5 5.1 8.3 7.4 2.0 0.0 3.5 0.2 7.0 0.1 0.1 20.5 9.0 5.6 5.4 1.5 0.1 6.9 0.1 0.7 0.0 0.1 0.3 6.3 0.5 8.1 0.2 81.8 0.2 6.7 8.9 1.4 11.6 0.6 2.6 5.2 18.8 10.7 0.1 4.1 25.9 76.9 4.1 0.1 0.8 3.7 3.5 0.8 0.1 4.8 3.3 0.9 3.6 18.8 33.2 5.9 4.1 14.2 7.2 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.2 0.0 0.0 7.2 9.2 77.2 30.6 12.2 8.9 14.4 5.6 14.7 2.7 13.8 12.3 2.4 0.0 2.0 45.7 1.1 0.5 1.7 0.0 2.8 28.4 0.5 0.6 3.1 0.0 0.6 1.8 22.9 0.4 1.9 0.3 1.9 0.0 7.8 2.2 6.9 1.5 1.2 1.3 286.7 0.0 0.1 4.8 1.1 3.3 0.0 0.7 0.7 0.0 0.1 15.2 304.9 0.6 0.0 0.3 0.6 1.5 2.5 0.2 1.8 18.7 0.0 1.4 2.1 184.0 125.6 0.0 3.1 2.6 0.9 0.4 0.3 1.0 0.8 10.9 0.0 2.9 3.2 0.8 1.9 0.4 0.4 0.0 2.2 3.7 1.3 0.3 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.9;intestine: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.7;Intestinal goblet cells: 42.5;Oligodendrocytes: 43.6;Paneth cells: 64.4;Proximal enterocytes: 48.5;Undifferentiated cells: 50.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 15.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 108.1;CAPAN-2: 74.1;HMC-1: 71.0;OE19: 191.5;THP-1: 122.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA007033: AB_1846529, HPA012049: AB_1846527" "unprognostic (2.45e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (3.06e-1)" "unprognostic (9.10e-3)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-1)" "prognostic favorable (4.13e-5)" "unprognostic (5.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-2)" 4.9 3.8 51.2 11.2 55.8 9.8 3.4 57.3 73.6 4.1 11.2 43.2 19.7 6.0 0.6 9.0 8.8 6.0 8.1 59.4 42.9 22.3 3.6 10.4 3.8 63.5 63.1 1.5 13.3 6.1 4.7 2.7 56.9 6.6 22.8 1.6 4.6 2.9 0.7 3.9 26.8 8.3 48.7 17.2 19.6 1.1 55.4 0.9 7.6 0.5 2.1 8.9 3.8 85.9 108.1 4.0 0.1 3.7 1.4 0.2 1.1 3.6 0.1 0.7 0.1 43.1 74.1 0.2 10.3 0.5 0.2 44.5 5.9 8.1 0.5 0.6 4.7 0.0 6.0 25.4 1.7 0.7 71.0 1.8 21.4 0.2 0.0 0.1 0.0 3.1 0.4 0.0 0.0 33.2 0.1 30.1 3.2 191.5 0.0 14.4 0.2 0.4 4.7 25.0 3.1 1.0 3.3 1.3 0.5 0.4 25.9 122.6 0.6 0.8 2.8 0.1 0.3 0.0 0.2 0.0 0.2 22.3 3.3 1.0 6.5 3.3 6.0 7.3 2.8 1.1 1.6 5.5 5.1 0.9 0.5 2.6 3.1 1.6 11.7 0.3 0.8 4.0 51.2 55.8 57.3 73.6 59.4 42.9 63.5 63.1 56.9 48.7 55.4 85.9 0.4 0.0 10.3 2.9 3.6 1.0 2.9 3.3 2.8 4.7 2.5 1.5 8.5 7.2 2.9 7.3 0.0 0.3 19.4 97.7 9.8 3.9 0.2 8.6 0.9 0.5 16.2 0.0 13.2 4.6 0.9 1.5 17.9 7.6 7.0 1.3 0.0 0.6 12.2 0.0 12.6 42.5 4.1 23.0 15.7 0.4 0.0 22.1 10.6 2.8 13.2 1.3 15.5 3.0 43.6 17.5 64.4 0.0 2.6 3.0 48.5 7.1 8.2 1.1 0.0 0.1 1.9 0.3 1.2 1.1 1.3 0.7 9.0 0.0 50.6 5.5 ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 61.7;Theca cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" 3.1 9.1 1.3 1.5 1.3 0.9 3.4 1.1 2.6 4.5 0.9 6.7 4.8 3.7 0.2 6.4 3.7 0.5 4.1 1.4 1.1 4.3 6.4 2.8 1.1 1.4 1.1 4.5 5.0 0.8 3.5 0.6 1.3 4.1 0.7 0.5 4.1 0.8 4.0 5.2 8.4 0.4 0.9 5.7 4.4 6.7 1.2 1.1 3.6 0.7 0.5 4.0 4.2 1.2 2.5 3.1 0.7 2.1 0.5 0.5 3.7 2.2 1.2 1.8 0.7 3.6 2.7 1.1 1.5 0.5 0.6 3.2 0.1 2.2 0.1 2.8 1.0 2.9 2.6 3.9 1.6 0.7 2.2 1.0 1.4 0.6 0.7 0.9 1.2 2.1 1.9 1.9 0.9 6.9 2.2 2.9 0.4 2.3 2.3 2.8 1.0 2.0 1.2 2.3 0.4 1.1 3.1 2.4 1.8 0.5 2.1 1.9 0.8 0.8 3.2 2.2 1.5 0.9 0.3 1.0 1.9 2.5 1.3 0.9 2.0 1.2 1.1 2.7 1.3 0.9 1.3 0.8 3.2 2.7 1.3 0.7 0.4 1.0 2.7 2.0 2.1 1.3 1.3 1.3 1.1 2.6 1.4 1.1 1.4 1.1 1.3 0.9 1.2 1.2 5.8 3.2 1.7 4.9 6.5 4.1 3.3 10.2 2.2 10.3 5.0 6.1 2.3 7.2 6.9 5.5 16.7 4.3 6.6 33.5 3.9 9.3 8.2 3.7 4.2 5.0 8.4 3.0 7.6 7.1 11.2 4.5 20.4 4.8 8.9 16.2 2.5 8.2 8.0 3.3 8.3 31.2 12.2 5.5 4.3 11.3 5.9 5.0 3.6 2.8 9.1 6.4 7.2 4.0 2.4 9.5 16.8 7.2 3.7 2.7 61.7 6.9 9.5 16.3 13.1 2.5 4.4 26.5 19.2 4.7 5.1 2.5 4.8 42.3 25.4 3.1 ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;Rod photoreceptor cells: 624.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" 104.4 70.0 96.4 60.7 119.7 65.9 89.1 86.7 117.7 96.5 46.4 127.9 65.5 121.4 57.9 71.9 96.3 69.0 111.2 99.2 90.9 74.1 53.7 93.5 65.3 91.5 100.4 129.5 56.4 67.5 70.1 66.0 92.3 86.1 62.7 269.1 61.9 107.3 166.3 69.4 92.3 110.2 76.0 88.9 84.3 53.2 113.2 76.0 71.7 115.0 62.1 115.3 82.9 116.2 74.7 61.2 142.0 73.8 205.8 152.6 53.2 123.2 146.9 125.6 105.3 90.5 91.8 38.7 63.0 212.3 146.6 46.6 107.5 103.4 104.3 49.9 49.4 109.5 50.4 87.9 100.4 65.8 74.7 151.6 95.2 110.4 44.0 130.1 158.5 71.9 116.0 90.8 145.1 43.7 203.7 91.6 80.0 67.9 85.7 89.1 78.6 45.7 91.2 162.2 84.8 110.0 88.9 35.8 76.9 107.0 84.2 61.7 193.4 102.1 52.4 84.7 103.0 72.5 63.3 48.9 98.2 80.4 100.9 20.1 7.6 35.5 19.1 7.3 17.6 23.8 10.6 16.3 12.0 31.2 9.8 11.8 10.5 27.2 11.4 25.4 14.8 16.0 96.4 119.7 86.7 117.7 99.2 90.9 91.5 100.4 92.3 76.0 113.2 116.2 89.3 70.5 45.4 141.3 66.5 26.9 29.8 33.0 27.9 99.5 41.2 41.5 78.0 40.0 46.3 60.7 402.4 35.5 84.0 51.3 15.6 37.3 48.5 43.9 61.2 89.4 57.7 57.9 85.7 45.8 32.5 72.9 39.8 58.1 37.3 53.0 84.3 41.8 41.8 111.0 83.2 39.3 28.5 51.6 42.2 35.9 77.6 47.4 35.6 72.1 58.3 233.8 120.5 68.9 178.6 53.2 39.4 121.9 49.7 35.8 48.6 44.6 40.4 624.3 98.6 58.4 73.1 45.3 33.2 30.5 36.7 36.5 55.6 80.7 45.1 33.0 ADD2 ADDB ENSG00000075340 "Adducin 2" P35612 2 70607618-70768225 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 66.5;brain: 52.8" "Cell type enhanced" "Detected in many" "Early spermatids: 31.7;Erythroid cells: 74.1;Excitatory neurons: 70.1;Horizontal cells: 139.7;Inhibitory neurons: 51.8;Late spermatids: 62.4" "Group enriched" "Detected in many" 5 "glioma: 5.2;testis cancer: 11.1" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.2;non-classical monocyte: 2.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HAP1: 33.9;JURKAT: 33.1;K-562: 46.5;NTERA-2: 86.7;RPMI-8226: 41.7;SCLC-21H: 42.8;U-251 MG: 47.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009796, HPA034509, HPA034510" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009796: AB_2223572, HPA034509: AB_2674201, HPA034510: AB_2674202" "unprognostic (3.58e-2)" "unprognostic (2.68e-4)" "unprognostic (3.83e-2)" "unprognostic (3.01e-4)" "unprognostic (1.94e-1)" "unprognostic (2.25e-3)" "unprognostic (1.35e-1)" "unprognostic (3.26e-1)" "unprognostic (3.49e-1)" "unprognostic (1.48e-1)" "unprognostic (1.20e-2)" "unprognostic (8.93e-2)" "unprognostic (4.47e-7)" "unprognostic (2.81e-4)" "unprognostic (1.77e-1)" "unprognostic (1.71e-3)" "unprognostic (1.31e-3)" 1.8 1.7 19.5 1.9 21.0 66.5 0.9 14.6 52.8 0.7 0.0 0.9 0.1 0.5 0.3 1.4 0.7 0.3 0.9 18.7 10.8 0.4 0.2 0.9 2.5 14.0 0.2 0.2 1.7 0.2 4.0 0.7 9.5 0.5 0.3 16.0 0.2 0.2 0.8 0.3 0.9 1.0 0.0 1.2 0.3 2.8 0.9 0.7 1.4 1.0 2.2 0.5 0.6 9.6 17.6 20.5 0.8 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 10.5 2.7 12.3 0.0 33.9 0.0 0.0 0.1 20.1 1.7 0.2 0.0 0.0 4.7 0.1 0.0 0.0 0.0 0.0 8.0 0.0 33.1 46.5 0.0 0.0 0.1 0.2 1.6 86.7 0.0 0.4 0.0 0.5 41.7 5.7 0.0 42.8 19.3 21.6 0.1 0.1 9.4 0.1 10.7 0.8 0.2 0.9 0.0 47.1 14.1 17.0 0.0 0.7 7.1 7.9 0.0 0.0 0.0 0.0 1.2 0.0 2.2 0.0 0.0 0.0 1.7 0.8 0.4 0.0 0.0 2.3 0.0 0.0 0.3 19.5 21.0 14.6 52.8 18.7 10.8 14.0 0.2 9.5 0.0 0.9 9.6 2.8 0.0 0.5 1.0 4.2 0.1 0.3 0.0 0.0 23.3 0.2 0.0 2.5 0.0 0.0 0.0 2.1 0.1 0.0 0.1 0.0 0.1 31.7 0.1 0.2 3.9 0.0 74.1 70.1 1.1 0.2 1.0 1.1 0.1 0.0 0.0 2.9 0.0 0.2 139.7 51.8 0.0 0.0 1.0 0.4 62.4 0.9 0.6 1.8 2.8 0.8 0.8 0.0 17.6 1.8 0.3 0.0 0.7 0.1 0.6 0.0 0.0 0.0 8.7 0.0 0.6 0.3 3.5 6.8 0.0 0.1 0.3 0.5 1.5 0.0 1.3 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 61.4" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Bipolar cells: 16.0;Excitatory neurons: 55.7;Inhibitory neurons: 13.8;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 13.2" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Region enhanced" "Detected in many" "hippocampal formation: 61.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 37.7;SH-SY5Y: 25.1;T-47d: 29.5;U-2 OS: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" 1.5 3.8 30.6 0.4 30.1 0.2 1.3 0.0 41.1 2.4 0.0 1.6 4.0 2.9 0.2 0.6 1.3 1.1 4.5 61.4 0.0 0.8 0.0 0.7 0.4 0.0 0.2 1.5 0.5 1.2 8.0 2.7 0.0 1.9 0.1 2.9 0.5 1.8 0.7 0.7 3.8 1.3 0.0 0.8 1.1 2.9 1.0 8.7 2.7 0.4 0.2 1.5 1.0 12.2 1.0 7.5 6.9 20.1 1.9 1.2 3.3 4.8 7.6 4.6 8.1 0.4 2.3 0.0 4.7 2.1 7.7 0.8 3.1 0.4 0.8 5.4 3.2 0.0 37.7 0.0 0.1 0.0 2.6 1.2 0.5 6.4 0.0 14.4 0.7 14.7 0.8 0.2 5.2 0.6 13.9 0.1 8.7 0.2 2.1 20.8 0.8 0.7 0.0 9.7 5.2 25.1 11.0 0.7 0.8 2.4 29.5 0.0 0.2 3.6 27.5 0.5 1.3 0.0 0.0 0.8 11.0 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 30.1 0.0 41.1 61.4 0.0 0.0 0.2 0.0 0.0 1.0 12.2 0.1 0.0 0.0 20.9 0.3 0.0 0.5 0.0 0.0 16.0 2.0 1.3 4.3 0.0 0.0 0.0 6.2 1.0 1.2 0.0 0.0 0.1 3.6 1.4 0.6 0.1 1.2 0.0 55.7 0.0 1.4 2.3 0.5 0.4 0.0 1.5 0.0 0.0 0.4 8.4 13.8 0.9 0.0 0.0 0.0 12.0 1.2 0.0 0.0 4.7 0.0 11.4 4.1 20.6 13.2 0.1 0.1 1.9 0.1 0.5 5.7 2.5 0.0 5.2 0.0 1.4 0.7 0.9 4.5 0.0 0.0 0.3 0.4 0.8 0.5 1.3 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 42.9;liver: 24.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 23.9;Paneth cells: 14.0;Proximal enterocytes: 39.4" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056451 Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" 0.1 0.1 0.0 0.9 0.0 2.2 0.1 0.2 0.1 0.5 0.0 5.2 42.9 0.3 0.0 0.2 0.6 0.7 0.2 0.0 0.0 0.1 24.7 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.2 2.9 0.2 0.1 0.0 0.1 0.2 39.3 1.5 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.0 0.2 5.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.0 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Excitatory neurons: 902.7;Inhibitory neurons: 646.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 252.8;hTEC/SVTERT24-B: 130.3;NTERA-2: 100.0;SH-SY5Y: 168.3;U-2197: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" 19.8 19.9 11.0 8.2 13.4 0.0 17.8 6.5 26.3 16.4 5.0 15.3 5.8 12.4 15.0 23.6 23.1 23.1 28.5 13.9 14.6 21.4 38.5 64.9 8.9 8.6 10.7 36.3 9.7 27.5 20.5 48.8 7.6 30.0 10.9 25.2 36.7 19.4 4.4 12.9 13.4 12.7 7.0 19.9 15.5 4.2 15.5 10.4 43.2 19.7 8.7 13.2 23.4 15.0 18.2 9.9 252.8 0.0 30.3 35.3 3.4 6.4 14.8 2.5 2.9 0.0 0.0 0.1 69.6 34.6 7.1 10.1 20.3 28.0 2.3 0.5 41.5 0.0 7.0 16.6 11.8 0.0 0.4 32.5 1.8 130.3 12.9 17.8 42.9 0.0 0.0 0.0 3.4 0.2 0.0 0.1 100.0 0.0 7.1 0.0 34.9 0.0 56.9 3.8 11.7 168.3 0.0 6.3 0.0 73.5 0.4 74.7 27.5 26.0 28.9 118.9 9.3 0.0 0.0 0.2 14.9 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 13.4 6.5 26.3 13.9 14.6 8.6 10.7 7.6 7.0 15.5 15.0 25.3 3.2 2.2 23.8 0.2 0.0 7.0 0.0 2.2 48.5 6.6 11.2 44.1 10.0 3.1 5.5 6.2 0.4 0.1 2.1 0.0 4.7 1.4 11.7 10.3 36.9 0.0 0.0 902.7 1.6 0.4 19.6 0.5 25.4 0.0 32.3 30.0 39.3 0.9 33.7 646.8 2.0 0.0 3.1 0.0 1.4 23.3 1.1 0.0 69.3 0.0 19.0 0.0 11.1 13.0 0.8 3.6 17.7 0.0 10.4 0.0 7.8 0.0 3.9 19.7 2.5 19.8 1.5 3.5 4.1 0.0 0.4 0.5 43.1 3.5 3.0 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADK AK ENSG00000156110 "Adenosine kinase" P55263 10 74151202-74709963 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Purine salvage" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 151.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 245.3;Inhibitory neurons: 287.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032876, HPA038391, HPA038409, HPA075222" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 920000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032876: AB_2242229, HPA038391: AB_2675990, HPA038409: AB_10675798, HPA075222: " "unprognostic (1.55e-3)" "unprognostic (1.09e-1)" "unprognostic (1.88e-1)" "unprognostic (2.62e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.93e-4)" "prognostic favorable (9.91e-4)" "unprognostic (2.64e-1)" "unprognostic (2.88e-1)" "unprognostic (1.55e-1)" "unprognostic (8.15e-3)" "unprognostic (2.51e-1)" "unprognostic (1.89e-3)" "unprognostic (2.03e-1)" "unprognostic (2.88e-2)" "unprognostic (4.97e-3)" "unprognostic (2.95e-2)" 23.9 15.5 13.0 16.9 18.7 28.6 27.4 13.5 17.7 17.5 11.6 17.9 16.9 10.8 16.5 47.3 16.5 11.4 27.2 13.9 15.2 35.8 151.2 24.4 22.8 14.0 15.0 8.3 18.8 44.2 14.9 26.6 16.5 14.9 19.5 16.1 20.0 16.0 41.5 33.9 12.4 14.8 14.2 15.0 12.1 15.5 14.1 27.0 38.2 47.1 34.5 24.5 24.7 15.8 177.3 37.4 37.2 50.5 37.1 54.7 88.2 140.8 105.4 103.8 114.5 114.0 172.6 86.3 34.2 57.7 51.3 151.1 44.1 150.1 167.0 59.1 51.3 55.6 59.8 122.8 41.7 87.6 22.5 51.1 95.5 77.4 191.7 79.0 91.2 38.7 41.8 28.4 78.8 101.7 102.5 129.0 9.9 80.0 276.3 100.6 63.7 69.4 117.1 92.7 29.5 33.8 63.6 239.7 49.5 34.7 159.7 69.3 82.8 34.3 67.0 93.2 123.0 40.5 48.3 98.1 65.0 127.6 22.1 2.3 34.2 4.1 12.9 65.5 29.9 103.7 28.2 24.1 83.1 155.0 21.3 19.2 11.1 20.7 80.4 57.6 55.7 36.3 13.0 18.7 13.5 17.7 13.9 15.2 14.0 15.0 16.5 14.2 14.1 15.8 9.8 83.3 75.8 136.5 84.2 94.2 73.5 102.0 105.9 16.3 26.2 26.0 67.8 38.6 72.4 31.3 56.3 136.7 25.9 11.0 92.0 83.2 80.7 40.6 18.8 14.9 10.8 27.7 245.3 67.5 139.5 27.0 23.0 55.6 21.5 9.7 17.2 130.1 39.3 11.8 287.7 12.1 44.7 25.2 50.0 26.9 16.8 33.7 48.0 198.6 44.1 14.1 11.3 140.8 165.4 62.7 10.4 12.0 39.1 92.1 5.0 64.5 33.5 25.0 6.6 20.4 26.0 17.4 14.3 96.7 97.0 107.3 32.7 17.0 20.5 66.3 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 36.9;liver: 11.4;lymphoid tissue: 11.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 41.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 36.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.9;HaCaT: 5.8;TIME: 9.8;U-2 OS: 7.9;U-251 MG: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" 4.2 1.8 3.4 0.3 16.1 0.0 1.9 0.0 7.9 0.4 0.0 0.7 0.4 0.9 1.4 0.3 3.0 0.5 2.0 6.0 3.4 3.9 11.4 4.0 1.2 0.0 36.9 2.9 0.4 0.5 0.6 0.3 6.3 0.6 0.3 0.5 0.3 0.7 0.7 0.9 1.4 0.4 0.0 11.6 0.7 0.2 4.5 0.1 1.5 0.7 0.3 0.4 0.6 5.2 0.4 4.5 0.3 0.0 1.9 0.8 0.1 0.5 0.1 0.5 0.2 0.0 3.8 0.0 11.9 3.4 4.4 5.8 0.0 0.5 0.3 0.0 0.2 0.0 1.7 0.0 4.1 0.0 0.0 2.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.7 0.0 3.8 0.0 0.4 0.0 0.0 0.3 0.3 1.7 0.1 0.0 9.8 0.1 7.9 0.0 6.6 0.0 0.0 0.0 2.9 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 16.1 0.0 7.9 6.0 3.4 0.0 36.9 6.3 0.0 4.5 5.2 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADRM1 "ARM1, GP110, Rpn13" ENSG00000130706 "Adhesion regulating molecule 1" Q16186 20 62302093-62308862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 369.5" "Cell type enhanced" "Detected in all" "Late spermatids: 1655.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "CACO-2: 727.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042266 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 28000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA042266: AB_10794044" "unprognostic (5.49e-2)" "unprognostic (5.14e-3)" "unprognostic (7.34e-2)" "unprognostic (6.16e-2)" "unprognostic (2.06e-2)" "unprognostic (1.06e-1)" "unprognostic (1.77e-3)" "unprognostic (2.14e-2)" "unprognostic (3.56e-2)" "unprognostic (2.13e-3)" "unprognostic (8.98e-2)" "unprognostic (3.50e-1)" "prognostic unfavorable (9.02e-6)" "unprognostic (4.15e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "unprognostic (8.47e-2)" 76.9 92.7 44.9 53.4 45.6 78.0 68.3 48.7 63.7 57.8 38.1 78.7 52.0 80.6 14.6 99.0 58.4 33.5 109.0 44.0 48.4 65.1 119.5 67.3 54.2 52.0 45.7 44.5 83.2 23.5 52.6 39.6 51.0 59.5 16.1 11.9 61.3 35.1 369.5 93.9 63.4 23.3 44.4 83.2 68.6 128.5 47.3 38.9 51.7 66.9 29.7 73.0 64.4 46.4 219.9 241.8 66.8 142.6 62.5 45.8 178.1 138.9 95.4 260.1 104.0 727.1 227.8 117.4 250.3 82.1 148.3 243.6 84.3 209.9 79.8 136.7 170.1 284.4 177.4 392.0 105.6 149.3 261.1 57.0 126.3 170.9 67.7 43.4 101.4 113.0 211.4 125.6 61.7 296.1 187.5 290.8 225.1 106.6 354.0 149.2 115.5 186.7 71.3 163.9 118.5 146.5 151.5 241.7 174.0 44.9 168.1 163.3 149.4 258.5 274.4 252.4 289.1 261.5 223.4 158.6 272.6 148.7 192.3 195.4 208.7 233.5 200.4 262.1 179.9 260.2 180.8 192.9 219.2 265.2 132.4 151.4 200.2 184.8 227.8 205.6 265.8 260.8 44.9 45.6 48.7 63.7 44.0 48.4 52.0 45.7 51.0 44.4 47.3 46.4 91.4 35.3 25.2 7.5 91.3 148.2 115.6 275.4 98.4 34.7 62.0 62.0 19.4 52.9 119.3 66.2 18.8 230.4 83.3 156.4 115.4 186.9 359.1 61.7 43.9 105.6 57.8 74.3 5.2 211.3 173.6 73.3 51.0 56.9 42.5 55.8 87.1 101.7 150.2 33.7 4.9 87.1 156.6 77.6 154.2 1655.0 72.4 89.8 97.8 3.7 126.5 73.0 83.4 4.0 8.5 247.5 129.7 86.9 118.2 145.7 118.6 139.0 96.2 31.7 65.7 49.9 177.0 135.2 204.2 108.0 148.0 423.0 86.1 57.5 95.2 144.6 ADSS2 ADSS ENSG00000035687 "Adenylosuccinate synthase 2" P30520 1 244408494-244451909 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 26.4;Cytotrophoblasts: 49.3;dendritic cells: 59.6;Extravillous trophoblasts: 97.2;Hofbauer cells: 35.8;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Approved "Plasma membrane,Cytosol" NA NA 690000 "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA024400: AB_1844623" "unprognostic (4.24e-3)" "unprognostic (2.63e-1)" "unprognostic (3.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.35e-1)" "unprognostic (7.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" 19.8 20.5 17.8 28.1 22.0 43.9 34.6 21.7 26.7 25.9 17.0 28.7 28.7 23.4 29.8 32.6 23.9 21.0 8.9 19.2 21.1 32.9 24.3 25.3 31.9 21.9 19.6 21.7 19.8 27.6 14.5 28.6 23.1 25.3 29.8 11.4 22.8 25.6 10.8 33.2 27.1 25.2 19.6 23.7 35.0 70.3 20.9 33.8 34.9 8.4 34.9 36.2 21.5 28.7 89.9 48.6 41.6 36.9 47.6 67.8 76.2 88.5 74.4 62.3 47.0 64.6 84.5 79.7 57.1 68.9 26.6 66.1 45.9 58.0 69.5 59.6 81.0 53.1 47.8 49.3 57.1 127.1 65.6 46.8 68.5 58.1 58.3 72.1 225.6 43.3 94.0 57.7 62.7 21.6 82.3 85.0 110.5 85.0 53.1 74.9 39.4 86.5 103.8 55.2 56.2 49.2 75.2 69.0 91.4 43.9 48.0 66.7 99.4 57.1 31.3 67.0 93.7 69.1 97.2 60.0 47.2 146.8 86.3 48.3 22.8 20.0 20.4 29.9 22.0 15.3 18.6 17.8 20.1 12.3 15.6 17.9 17.5 23.6 33.6 7.9 22.3 18.8 17.8 22.0 21.7 26.7 19.2 21.1 21.9 19.6 23.1 19.6 20.9 28.7 26.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 49.3 59.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 97.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 54.0 11.0 0.0 0.0 0.0 AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.5;parathyroid gland: 68.7;thyroid gland: 82.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 40.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 122.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "A-431: 74.4;CAPAN-2: 77.4;EFO-21: 56.4;HaCaT: 98.7;RPMI-8226: 51.3;RPTEC TERT1: 59.7" "Low region specificity" "Detected in all" HPA037843 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" "HPA037843: AB_10669990" "unprognostic (2.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (5.06e-3)" "unprognostic (4.14e-2)" "unprognostic (9.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.11e-1)" "unprognostic (3.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.86e-1)" 7.6 2.4 15.7 4.2 12.9 0.1 10.2 21.5 13.1 21.8 5.9 13.0 3.9 23.9 13.2 9.3 22.9 4.5 4.7 11.8 12.4 17.6 1.7 5.3 4.3 12.9 12.8 15.1 11.9 68.7 2.4 18.4 13.6 13.1 5.1 3.7 6.9 23.9 3.0 9.8 6.4 18.9 13.6 64.5 5.9 1.4 13.3 13.5 82.2 4.4 7.6 5.9 14.7 13.5 74.4 10.8 10.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 77.4 0.1 56.4 0.6 1.1 98.7 0.2 27.2 0.2 1.5 0.1 0.0 0.7 0.0 3.0 0.0 2.7 0.0 28.9 8.1 7.1 0.3 0.3 2.8 0.0 0.2 0.0 3.1 1.9 0.1 0.5 2.0 0.5 0.9 0.8 51.3 59.7 0.6 0.3 0.5 2.3 1.7 2.9 16.0 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.6 1.1 1.2 0.0 1.6 0.3 0.9 0.1 0.4 0.0 0.1 1.8 0.6 15.7 12.9 21.5 13.1 11.8 12.4 12.9 12.8 13.6 13.6 13.3 13.5 14.6 0.0 0.0 0.7 1.2 12.4 7.3 3.1 5.2 0.8 1.8 5.3 2.2 0.0 1.8 40.5 0.0 1.5 2.4 8.1 0.0 0.6 1.0 5.3 7.4 14.5 0.0 0.8 6.5 14.3 1.2 10.7 3.1 9.5 0.0 0.3 13.2 0.0 0.5 1.7 10.1 1.8 0.0 0.0 3.7 3.0 3.1 0.5 5.4 34.7 0.6 3.2 0.0 122.6 0.6 23.2 1.7 1.9 0.1 3.7 2.2 0.4 1.5 0.6 19.7 21.4 24.7 0.0 0.8 2.3 6.8 0.3 3.4 2.4 2.2 4.3 AFDN "AF-6, AF6, MLLT4" ENSG00000130396 "Afadin, adherens junction formation factor" P55196 6 167826922-167972023 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Cell adhesion" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Alveolar cells type 1: 169.9;Breast glandular cells: 119.1;Endometrial ciliated cells: 194.3;Glandular and luminal cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013496, HPA030212, HPA030213, HPA030214, HPA030215, HPA049868" Approved Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB013496: , HPA030212: AB_10599291, HPA030213: AB_10601340, HPA030214: AB_10601005, HPA030215: AB_10601556, HPA049868: AB_2680924" "prognostic unfavorable (7.43e-5)" "unprognostic (2.66e-3)" "unprognostic (2.07e-2)" "unprognostic (2.61e-1)" "unprognostic (1.13e-1)" "unprognostic (9.06e-2)" "unprognostic (4.12e-1)" "unprognostic (3.12e-2)" "unprognostic (4.12e-1)" "unprognostic (1.09e-3)" "unprognostic (1.75e-1)" "unprognostic (1.73e-2)" "unprognostic (5.56e-2)" "unprognostic (5.43e-3)" "unprognostic (1.59e-1)" "unprognostic (4.72e-2)" "unprognostic (5.68e-2)" 39.7 15.0 25.1 23.1 34.8 5.5 49.5 27.2 27.9 46.0 35.1 55.3 53.1 35.8 39.8 126.3 63.8 33.6 47.3 21.0 29.7 45.0 66.8 57.0 10.9 30.2 30.0 31.2 61.2 32.8 38.3 44.9 29.5 47.0 62.7 47.1 79.0 28.6 34.0 54.7 71.1 23.9 12.3 34.2 50.6 31.3 31.2 7.3 51.4 28.4 27.3 29.2 61.8 35.3 67.7 20.7 141.2 50.8 13.5 11.3 104.8 26.8 13.7 22.7 27.9 88.8 41.1 12.0 48.3 16.3 35.5 31.8 59.2 55.1 40.3 76.1 61.1 0.4 9.1 67.9 20.3 7.7 30.8 8.0 36.2 38.1 89.0 36.1 42.8 25.6 137.4 45.5 14.9 29.2 0.8 0.6 34.7 95.6 9.5 43.6 37.1 51.2 41.3 32.5 65.1 39.6 27.2 101.7 40.5 131.1 12.2 2.8 62.9 10.6 50.5 45.7 44.9 0.8 59.3 24.5 31.4 15.4 93.7 0.0 0.1 0.0 0.3 0.1 0.2 1.1 0.3 0.1 0.2 0.7 0.0 0.1 0.9 0.0 0.1 0.0 0.2 0.0 25.1 34.8 27.2 27.9 21.0 29.7 30.2 30.0 29.5 12.3 31.2 35.3 173.8 169.9 89.3 0.0 6.4 0.0 0.0 0.0 0.0 0.0 119.1 83.3 0.0 0.0 40.9 95.6 0.0 30.6 4.7 0.0 21.5 70.1 0.0 194.3 42.0 36.3 0.0 0.0 0.0 39.4 35.0 20.5 0.0 273.4 8.8 65.0 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 0.0 0.0 10.9 0.0 0.0 0.0 0.0 65.7 0.0 0.0 4.5 0.0 0.0 35.0 46.7 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 42.1 5.6 13.2 0.0 0.0 AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 6.4;Distal tubular cells: 9.8;Hofbauer cells: 5.7;Proximal tubular cells: 6.3;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA030154: AB_10600769, HPA030155: AB_10601232, HPA030659: AB_10602415" "unprognostic (9.76e-5)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (7.04e-2)" "unprognostic (2.57e-1)" "unprognostic (5.53e-2)" "unprognostic (2.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.73e-2)" "unprognostic (9.61e-2)" "unprognostic (8.40e-8)" "unprognostic (2.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 1.8 2.1 2.2 1.3 2.7 2.1 2.2 2.0 3.3 1.7 2.7 2.6 4.2 1.5 1.9 1.6 2.2 1.5 4.6 1.7 1.9 5.0 3.7 1.7 1.8 1.8 2.0 1.7 2.1 5.4 1.5 2.2 2.0 1.6 3.1 3.1 1.8 1.7 3.7 1.2 3.0 1.7 1.7 2.0 2.8 10.7 2.7 2.3 3.0 4.0 2.1 1.7 1.1 3.2 2.7 1.4 3.4 6.1 3.5 5.1 3.3 3.0 4.4 4.8 4.7 5.7 3.3 4.8 3.8 4.7 5.8 1.5 4.4 4.5 5.4 2.8 2.6 5.7 1.8 6.6 3.5 5.3 2.7 4.7 3.6 3.6 5.8 3.1 2.6 3.5 5.9 2.2 4.5 2.6 0.9 4.8 2.2 4.6 2.8 3.3 4.6 2.8 6.1 2.9 3.7 3.2 2.4 3.5 6.4 4.5 2.8 9.8 3.2 2.9 0.7 2.6 3.4 1.5 2.6 3.7 3.6 6.0 4.5 0.0 1.6 2.8 1.0 1.2 1.3 2.5 1.5 1.9 1.4 3.4 2.1 1.4 0.4 2.4 4.3 1.6 2.3 0.7 2.2 2.7 2.0 3.3 1.7 1.9 1.8 2.0 2.0 1.7 2.7 3.2 2.4 0.0 4.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 5.0 3.7 0.0 6.4 1.1 0.0 9.8 3.1 0.0 2.6 2.6 2.2 0.0 0.0 0.0 3.8 4.6 1.2 0.0 1.8 2.5 5.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.0 6.3 5.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.2 0.9 4.5 0.0 0.0 AGER "RAGE, SCARJ1" ENSG00000204305 "Advanced glycosylation end-product specific receptor" Q15109 6 32180968-32184322 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 19 "lung: 728.3" "Cell type enriched" "Detected in many" 22 "Alveolar cells type 1: 2394.2" "Cancer enhanced" "Detected in all" "lung cancer: 27.2;thyroid cancer: 20.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 2.5;JURKAT: 3.0;RPTEC TERT1: 2.2;U-266/70: 2.4;U-266/84: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB011682, HPA064436, HPA069474" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cell Junctions" "Secreted in other tissues" NA NA 5360000 100000 "Cluster 19: Lung - Lung function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cell Junctions" "Nucleoli fibrillar center" "CAB011682: AB_2258049, HPA064436: AB_2685264, HPA069474: " "unprognostic (9.37e-2)" "unprognostic (3.70e-1)" "unprognostic (2.37e-2)" "unprognostic (1.14e-1)" "unprognostic (4.55e-2)" "unprognostic (1.59e-3)" "unprognostic (4.36e-2)" "unprognostic (1.00e-1)" "unprognostic (4.38e-2)" "unprognostic (1.27e-1)" "prognostic favorable (3.41e-4)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.01e-7)" "unprognostic (3.57e-1)" "unprognostic (3.70e-2)" "unprognostic (4.44e-2)" "prognostic favorable (2.74e-6)" 2.2 1.7 0.1 1.1 0.1 0.5 1.6 0.1 0.4 4.4 0.2 3.9 0.6 2.5 1.9 2.1 4.5 0.1 2.7 0.2 0.1 6.4 2.7 728.3 0.6 0.2 0.1 4.8 1.7 0.0 5.0 0.4 0.2 4.9 0.8 0.4 1.6 0.0 1.0 2.0 3.2 0.1 0.1 7.0 2.0 2.2 0.2 0.8 39.2 0.1 0.5 2.9 3.2 0.3 0.1 0.0 0.0 0.3 0.1 0.9 1.5 0.0 0.1 0.0 0.1 0.0 0.2 0.1 1.0 0.2 0.0 1.0 0.1 0.3 0.2 0.2 2.5 0.7 0.0 0.0 0.0 0.3 1.1 0.0 0.1 0.0 0.1 0.2 0.1 3.0 0.0 0.3 0.1 1.3 0.1 0.9 0.0 0.1 0.0 0.0 0.1 0.1 2.2 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.5 0.0 0.1 0.0 0.6 0.8 0.1 2.4 2.0 0.9 1.1 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.3 5.4 2394.2 107.9 5.9 4.9 0.9 1.5 2.0 2.8 5.1 1.5 2.9 3.0 4.3 20.9 1.8 0.0 1.1 2.7 1.1 0.0 1.5 0.4 1.1 2.6 4.1 0.0 4.4 0.5 1.0 0.9 3.0 1.5 1.9 17.7 3.1 2.9 2.0 1.3 6.7 0.6 1.3 0.0 5.3 6.5 1.2 1.8 5.3 1.8 4.7 4.8 4.6 2.1 2.5 1.3 1.1 2.7 1.2 3.3 2.6 0.8 0.3 5.6 3.4 6.6 1.2 2.6 0.1 1.2 1.6 1.8 2.2 6.2 1.7 1.2 0.9 AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 94.5;Collecting duct cells: 156.3;Ductal cells: 91.2;Pancreatic endocrine cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 205.3;EFO-21: 236.9;HaCaT: 210.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 20000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" 11.4 2.7 8.7 4.3 5.5 2.0 14.7 0.1 13.9 14.4 8.9 10.9 7.9 13.7 1.8 15.6 14.6 7.3 9.9 5.8 0.0 44.0 13.3 19.8 1.6 16.0 1.4 5.5 28.0 3.9 8.3 5.1 6.1 14.4 1.5 0.8 24.8 8.2 4.2 16.5 9.6 2.9 2.2 6.3 13.4 9.7 7.9 2.6 34.7 2.0 1.6 16.2 11.6 9.9 124.3 75.1 11.1 42.7 2.4 3.0 122.1 61.4 19.6 39.7 24.5 60.6 205.3 2.3 236.9 9.6 19.3 210.1 4.1 75.6 4.7 4.4 28.6 0.2 102.1 54.2 17.1 1.8 23.1 10.5 32.2 12.6 27.7 55.9 7.2 1.7 25.7 0.7 3.5 93.0 0.8 17.6 28.4 39.7 54.5 20.1 27.0 18.5 70.0 51.4 2.4 25.9 124.8 129.1 121.9 12.7 114.8 7.4 107.8 47.7 169.0 6.4 50.6 1.2 0.6 3.5 30.4 10.8 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 5.5 0.1 13.9 5.8 0.0 16.0 1.4 6.1 2.2 7.9 9.9 27.4 25.6 8.8 15.0 2.2 15.0 9.2 94.5 19.9 1.4 32.7 39.2 3.1 61.5 42.0 156.3 8.4 1.6 0.9 29.9 1.9 91.2 0.4 37.2 14.0 29.0 6.7 1.7 23.1 16.9 4.8 8.7 17.9 62.7 2.5 7.2 21.8 13.1 4.1 5.0 7.8 11.6 36.7 2.9 10.1 1.0 5.6 4.3 24.9 12.2 15.6 10.5 0.0 15.1 29.6 87.3 17.7 2.6 0.6 22.3 18.1 16.0 33.0 5.3 6.6 3.3 23.3 0.8 11.4 11.7 6.0 1.2 2.9 2.3 18.3 21.2 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AIFM2 "AMID, FLJ14497, PRG3" ENSG00000042286 "Apoptosis inducing factor mitochondria associated 2" Q9BRQ8 10 70098223-70132934 "Predicted intracellular proteins" "DNA-binding, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 173.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028961, HPA042309, HPA075576" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cytosol" "HPA028961: AB_2672844, HPA042309: AB_10796575, HPA075576: " "unprognostic (6.62e-2)" "unprognostic (2.73e-1)" "unprognostic (4.29e-1)" "prognostic favorable (2.80e-4)" "unprognostic (7.26e-3)" "unprognostic (2.57e-2)" "unprognostic (7.95e-3)" "unprognostic (2.80e-1)" "unprognostic (5.31e-2)" "unprognostic (8.90e-2)" "unprognostic (2.23e-1)" "unprognostic (1.53e-1)" "unprognostic (4.49e-1)" "unprognostic (4.59e-3)" "unprognostic (2.17e-1)" "unprognostic (1.11e-1)" "prognostic favorable (2.92e-4)" 39.6 13.5 7.5 6.3 8.1 1.9 31.2 7.3 8.0 6.9 8.6 12.9 9.3 7.8 9.0 13.3 6.8 5.0 17.0 6.9 7.7 10.4 21.9 9.3 5.1 8.2 7.3 7.9 5.0 3.2 5.6 4.1 6.9 9.9 7.1 2.4 7.6 7.7 9.8 5.6 11.5 5.0 6.2 7.7 9.9 3.9 8.3 2.4 14.6 7.3 3.6 12.0 6.3 6.5 26.5 45.2 1.1 11.3 26.2 9.8 0.3 10.4 25.5 21.0 23.6 35.3 49.8 3.8 25.8 14.5 27.5 27.9 12.7 3.8 5.9 50.8 1.9 0.2 27.3 173.3 56.1 0.3 6.4 13.3 8.4 33.8 7.2 13.2 9.5 1.7 20.5 21.9 11.0 33.5 1.2 1.3 4.5 21.2 14.6 0.8 4.2 12.4 11.4 19.2 3.6 0.8 19.1 16.6 29.8 1.8 0.7 7.2 12.0 0.5 25.3 15.6 30.8 16.2 32.7 7.3 14.0 0.9 13.9 1.0 0.5 0.5 1.8 0.5 1.5 1.7 0.6 1.5 0.4 1.5 0.8 1.3 0.5 4.0 0.5 0.2 1.3 0.7 7.5 8.1 7.3 8.0 6.9 7.7 8.2 7.3 6.9 6.2 8.3 6.5 11.6 6.4 14.1 7.2 5.0 2.3 15.0 8.4 2.8 5.7 5.5 4.7 13.8 8.6 10.5 18.4 0.0 13.9 1.4 53.1 3.9 40.7 24.1 6.0 7.7 4.8 12.0 7.0 8.2 21.9 3.0 11.2 14.3 6.2 11.4 22.3 1.8 25.0 10.2 1.7 5.2 7.1 14.2 3.3 3.3 47.0 5.3 6.7 8.8 4.7 34.4 4.8 1.0 5.5 3.5 40.8 22.7 4.5 17.0 14.6 28.7 22.6 9.5 2.1 19.7 11.8 12.8 6.2 3.9 5.1 1.4 18.6 3.8 8.8 13.7 20.4 AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 84.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA028901: AB_10602227" "unprognostic (2.17e-2)" "unprognostic (3.48e-2)" "unprognostic (5.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-3)" "unprognostic (3.88e-1)" "unprognostic (7.69e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (3.21e-2)" "unprognostic (3.21e-2)" "unprognostic (2.49e-2)" "unprognostic (7.15e-2)" "unprognostic (2.16e-2)" "unprognostic (5.20e-2)" 11.4 13.3 10.5 12.3 12.4 10.6 12.3 11.4 13.6 11.5 15.1 11.4 9.5 12.4 8.8 10.6 10.4 10.7 7.4 11.3 11.6 13.1 8.1 11.0 16.0 9.9 10.7 13.5 8.4 15.1 7.5 12.2 10.6 10.9 11.6 15.3 9.8 11.7 7.2 9.5 10.1 13.3 10.4 14.9 11.1 14.2 13.8 14.1 15.1 9.4 12.5 11.3 10.2 14.7 18.1 21.3 13.9 9.7 18.0 22.5 25.7 20.6 21.9 22.4 26.7 23.2 10.6 15.4 13.6 16.4 19.4 18.8 18.1 17.2 30.4 12.8 15.4 13.2 20.2 11.4 17.0 9.7 20.7 19.1 21.1 20.5 25.1 25.0 18.3 18.5 8.6 7.5 23.6 13.1 18.1 14.3 9.1 25.1 7.2 11.8 45.5 8.1 18.7 11.3 4.7 14.1 23.6 11.0 19.7 84.8 26.7 10.7 16.1 17.2 14.2 14.8 19.3 9.3 10.7 18.8 22.8 11.5 17.0 4.9 9.7 12.6 8.6 14.4 8.0 8.4 8.4 9.4 8.5 9.2 10.0 8.9 33.8 7.6 13.9 6.3 7.1 4.3 10.5 12.4 11.4 13.6 11.3 11.6 9.9 10.7 10.6 10.4 13.8 14.7 13.4 3.2 12.3 71.2 24.4 7.0 9.7 8.9 10.2 24.6 11.1 9.0 8.4 21.5 11.9 5.5 16.7 14.9 16.8 15.8 1.9 9.9 12.8 11.0 14.8 12.6 7.2 15.2 55.1 7.2 11.1 11.7 14.8 10.8 10.1 18.0 16.8 13.6 16.5 33.7 54.6 9.9 12.2 35.1 10.5 13.9 15.2 21.4 5.4 61.8 32.3 11.7 25.7 51.8 78.5 7.9 15.2 13.9 11.2 15.6 14.6 5.7 15.3 23.2 19.7 10.5 11.2 23.1 23.6 11.0 7.7 14.0 19.0 15.6 11.8 12.1 AKAP11 "AKAP220, DKFZp781I12161, FLJ11304, KIAA0629, PPP1R44, PRKA11" ENSG00000023516 "A-kinase anchoring protein 11" Q9UKA4 13 42272152-42323261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039089 Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane, Cytosol" "HPA039089: AB_10674279" "unprognostic (6.43e-2)" "prognostic unfavorable (9.26e-4)" "unprognostic (4.91e-1)" "unprognostic (6.89e-2)" "unprognostic (1.92e-1)" "unprognostic (7.34e-2)" "unprognostic (1.16e-1)" "unprognostic (1.83e-1)" "unprognostic (7.91e-2)" "unprognostic (2.15e-3)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (7.49e-3)" "unprognostic (7.44e-2)" "unprognostic (1.49e-1)" "unprognostic (6.02e-2)" "unprognostic (1.10e-1)" 12.6 13.9 14.2 11.5 27.3 3.7 11.6 10.9 19.9 16.6 0.0 10.0 7.5 13.5 15.4 10.6 10.4 10.2 11.6 22.7 12.7 13.3 10.7 10.9 15.8 8.7 15.3 14.7 6.9 11.7 9.3 7.7 8.5 11.3 10.5 32.5 8.0 12.3 5.6 9.9 8.4 12.2 11.5 13.3 10.4 20.6 16.4 13.2 14.0 10.9 13.8 10.4 8.6 18.9 15.2 15.3 18.4 11.0 23.6 28.7 8.0 20.2 16.7 11.9 11.1 16.9 12.4 31.2 7.6 22.7 12.5 17.7 16.1 16.9 22.7 33.4 7.5 8.8 10.6 8.4 18.5 22.2 20.8 21.2 17.0 24.4 21.2 17.5 17.8 15.5 29.5 12.3 24.3 11.4 13.0 7.2 10.9 22.3 7.1 10.7 12.9 15.1 11.9 11.1 7.8 11.3 15.5 10.1 7.1 8.5 8.7 11.8 24.8 20.1 10.4 30.7 15.4 4.7 6.3 15.8 25.7 11.1 14.4 1.7 0.3 0.4 0.5 0.3 0.7 0.9 0.8 0.5 0.3 1.1 0.6 0.6 0.1 1.6 0.5 0.5 1.0 0.2 14.2 27.3 10.9 19.9 22.7 12.7 8.7 15.3 8.5 11.5 16.4 18.9 41.9 25.6 30.5 58.8 42.8 12.2 13.7 15.4 14.8 67.3 20.4 14.6 44.9 12.8 32.6 29.5 37.5 4.4 21.2 12.9 1.9 12.7 14.0 24.3 33.1 25.5 21.0 16.6 105.4 9.5 3.8 27.5 24.5 25.7 34.2 25.9 29.3 22.6 12.5 42.1 105.4 14.9 20.3 24.8 21.6 14.6 21.8 25.0 8.8 46.9 21.6 69.8 16.5 69.9 91.3 12.7 15.4 33.4 27.0 12.2 9.4 20.5 33.1 38.3 19.7 33.9 27.1 49.2 32.8 20.6 16.9 2.5 25.4 28.3 12.3 13.4 AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 352.6;Endothelial cells: 278.4;Fibroblasts: 270.0;Muller glia cells: 583.0;Pancreatic endocrine cells: 322.1;Spermatocytes: 325.4" "Cancer enhanced" "Detected in all" "testis cancer: 39.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 235 "basophil: 37.2" "Lineage enriched" "Detected in single" 235 "granulocytes: 37.2" "Cell line enhanced" "Detected in many" "REH: 193.0;TIME: 188.2;U-251 MG: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB026379: , HPA006344: AB_1078118, HPA056230: AB_2683073" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (9.90e-3)" "prognostic unfavorable (7.08e-4)" "unprognostic (2.61e-2)" "unprognostic (8.88e-2)" "unprognostic (5.05e-2)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.34e-1)" "unprognostic (8.26e-3)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (4.51e-3)" "unprognostic (1.10e-3)" "unprognostic (3.51e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-2)" 105.6 16.0 13.8 17.1 16.6 2.2 59.7 99.7 57.5 19.8 4.5 60.1 8.6 31.1 9.3 18.6 31.2 31.5 51.8 14.7 66.8 35.8 30.6 44.3 6.9 67.0 35.3 87.8 10.8 1.6 23.3 38.3 74.7 23.1 13.2 109.4 6.5 20.8 11.9 9.4 24.9 42.9 10.9 14.3 25.6 100.0 39.4 5.9 22.1 14.5 3.4 33.0 21.2 24.3 7.8 37.8 53.2 0.1 98.2 145.9 18.8 43.9 23.7 19.3 19.4 0.9 141.6 0.0 17.1 33.2 160.4 1.0 102.2 32.5 17.2 50.2 37.6 0.6 40.8 35.6 10.9 0.0 9.6 104.0 0.0 81.9 4.3 25.4 127.8 0.6 9.8 0.9 70.7 0.5 0.3 0.1 33.3 0.1 43.9 193.0 2.3 0.2 110.2 6.3 37.9 22.0 14.1 0.5 24.9 74.6 2.8 0.5 188.2 2.6 34.0 110.4 202.9 0.4 0.1 0.2 63.2 0.1 37.4 37.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.6 99.7 57.5 14.7 66.8 67.0 35.3 74.7 10.9 39.4 24.3 352.6 12.8 16.2 34.3 6.8 19.6 19.6 63.2 1.2 14.5 1.2 3.9 12.1 5.7 31.1 51.5 2.1 2.4 0.9 1.2 1.9 107.0 101.4 14.2 195.4 278.4 1.8 3.2 75.8 6.7 10.1 270.0 3.6 31.6 64.2 14.7 194.5 4.8 26.9 0.0 33.3 0.7 4.1 15.7 45.4 116.3 39.7 13.9 58.7 37.5 0.6 583.0 1.0 59.8 5.1 322.1 1.1 110.6 6.7 49.5 0.0 89.4 6.0 31.0 98.6 208.3 243.0 325.4 33.0 1.6 11.4 10.0 5.1 9.3 2.5 105.3 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 AL139300.1 ENSG00000256500 "Novel protein" 14 103562962-103685924 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.7;tongue: 16.5" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;granulocytes: 2.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "HPA044617, HPA052450" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (1.56e-1)" 4.3 2.6 0.9 2.9 1.0 0.8 1.3 0.9 5.2 1.2 0.2 1.4 0.0 0.8 0.2 1.6 0.9 0.1 12.8 1.4 1.6 0.5 0.5 1.0 1.6 1.0 1.7 1.0 2.5 7.5 3.8 0.1 1.6 1.4 0.0 3.5 1.6 1.1 31.7 0.6 0.7 3.1 0.7 0.4 0.7 9.4 1.1 2.9 0.1 16.5 1.7 3.4 0.5 1.2 8.1 15.9 18.5 0.6 8.2 7.8 5.6 25.7 19.7 29.3 17.0 9.5 12.1 22.0 17.2 19.2 19.3 5.5 12.4 13.3 17.4 6.7 0.0 8.7 6.1 8.7 9.7 10.8 3.4 8.6 0.6 13.5 11.0 14.5 15.2 13.7 11.6 3.4 21.4 15.4 18.9 1.2 12.1 19.5 13.9 7.7 12.1 11.4 13.6 9.0 22.1 12.2 14.6 5.7 12.1 6.2 13.0 6.6 8.4 11.3 9.2 16.9 10.4 6.4 8.6 25.6 19.6 3.4 9.8 0.2 0.8 1.1 0.5 1.3 0.7 0.3 0.7 0.9 0.4 1.3 1.0 0.4 0.7 0.6 1.6 1.5 1.4 0.3 0.9 1.0 0.9 5.2 1.4 1.6 1.0 1.7 1.6 0.7 1.1 1.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 AL353671.1 ENSG00000288684 "Novel protein" 9 32455323-32552603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 5.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.4" "Low cell line specificity" "Detected in some" "HPA047193, HPA073217" Uncertain Approved "Plasma membrane,Cytosol" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 36: HEL - Hemostasis" "Plasma membrane, Cytosol" "HPA047193: AB_2679978, HPA073217: " 0.7 0.1 0.5 0.3 0.5 0.2 0.2 0.4 0.5 0.4 0.5 0.3 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.3 0.6 0.3 0.5 0.2 0.0 0.9 0.9 0.1 0.0 0.8 0.1 0.9 0.2 0.2 0.0 0.2 0.4 0.4 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.8 0.5 0.1 0.5 0.1 0.2 0.9 0.3 0.5 0.6 0.1 0.8 0.7 0.2 1.4 0.7 0.7 1.4 0.7 0.0 0.4 0.2 0.6 0.9 0.1 0.2 0.7 0.0 1.3 0.4 1.8 0.7 0.0 0.4 0.8 0.1 0.7 0.5 0.6 1.0 0.8 1.1 1.3 0.2 0.1 0.7 0.0 0.3 0.7 0.3 0.9 0.1 1.4 0.3 0.1 0.3 0.7 0.6 1.4 0.5 0.2 0.2 0.1 0.1 0.0 0.5 0.6 0.5 0.6 0.4 0.3 0.5 0.4 0.4 0.2 0.0 1.7 0.4 1.6 0.5 0.4 0.3 0.5 0.5 0.6 0.3 0.3 0.6 0.5 5.4 0.4 0.3 0.1 0.8 0.3 0.5 0.5 0.4 0.5 0.3 0.6 0.9 0.9 0.9 0.5 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL355315.1 ENSG00000249967 "Novel protein" 10 97584374-97673910 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "tongue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.2;EFO-21: 1.3;GAMG: 1.0;HBEC3-KT: 1.1;hTERT-RPE1: 1.9" HPA076857 Uncertain "Plasma membrane" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Plasma membrane" "HPA076857: AB_2686817" 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.2 0.0 0.4 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 1.3 0.2 1.0 0.7 0.0 1.1 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.2 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL357075.4 ENSG00000288520 "Novel protein" G9CGD6 6 154159828-154510114 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 1.4;HMC-1: 1.0" "HPA028708, HPA028710, HPA049651" Uncertain Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 3: HMC-1 - Innate immune response" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442, HPA049651: AB_2680841" 0.2 0.1 0.0 0.1 0.2 0.1 0.3 0.3 0.4 0.5 0.5 0.3 0.5 0.7 0.1 1.0 0.4 0.3 0.2 0.0 0.2 0.8 0.6 0.2 0.0 0.3 0.2 0.5 1.4 0.0 0.5 0.3 0.4 0.3 0.1 0.0 0.3 0.0 0.0 0.6 0.6 0.3 0.5 0.3 0.6 0.2 0.0 0.2 0.0 0.4 0.5 0.6 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.1 0.3 0.0 0.1 0.4 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.4 0.0 0.2 0.3 0.2 0.3 0.3 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL358113.1 ENSG00000285130 "Novel protein" 9 69035747-69255187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 3.2;Alveolar cells type 2: 4.6;Endometrial ciliated cells: 3.8;Glandular and luminal cells: 3.8;Respiratory ciliated cells: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "REH: 1.0" "HPA001813, HPA068304, HPA070714" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA001813: AB_1080764, HPA068304: AB_2685970, HPA070714: AB_2732161" 0.0 0.3 0.1 0.4 0.1 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.6 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.1 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.7 0.0 0.1 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.8 0.5 0.1 0.1 0.1 0.1 0.5 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.4 3.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 3.8 0.6 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 3.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 AL645922.1 ENSG00000244255 "Novel complement component 2 (C2) and complement factor B (CFB) protein" 6 31927698-31952048 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.5;Club cells: 3.1;Fibroblasts: 1.2;Respiratory ciliated cells: 5.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000951, HPA001817, HPA001832" Approved Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 49: Ciliated cells - Cilium organization" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "unprognostic (7.68e-2)" "unprognostic (1.86e-2)" 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.9 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALDH3A1 ALDH3 ENSG00000108602 "Aldehyde dehydrogenase 3 family member A1" P30838 17 19737984-19748943 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 496.1;salivary gland: 128.0;stomach 1: 224.8" "Group enriched" "Detected in many" 4 "Basal respiratory cells: 389.5;Basal squamous epithelial cells: 274.3;Club cells: 150.1;Gastric mucus-secreting cells: 437.9;Respiratory ciliated cells: 412.7;Squamous epithelial cells: 342.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 64.4;lung cancer: 60.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "A549: 5094.7;OE19: 6071.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB045957, HPA051150, HPA063783" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 52000 "Cluster 22: NK-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB045957: AB_11127164, HPA051150: AB_2681364, HPA063783: AB_2685122" "unprognostic (3.11e-5)" "unprognostic (1.20e-2)" "unprognostic (1.08e-1)" "unprognostic (7.04e-3)" "unprognostic (4.36e-3)" "prognostic favorable (7.55e-5)" "unprognostic (3.12e-1)" "unprognostic (3.84e-1)" "unprognostic (2.10e-1)" "unprognostic (1.67e-1)" "unprognostic (2.69e-3)" "unprognostic (5.54e-2)" "unprognostic (1.72e-1)" "unprognostic (3.84e-2)" "unprognostic (1.83e-1)" "unprognostic (2.88e-2)" "unprognostic (7.23e-2)" 1.7 1.0 0.4 1.3 0.7 0.1 3.2 0.3 0.4 6.7 17.5 4.5 6.2 0.3 0.2 496.1 5.5 10.3 0.3 1.0 0.4 1.3 1.9 10.9 0.5 0.6 2.1 0.4 0.5 0.0 0.9 0.0 0.5 1.9 3.3 0.1 128.0 1.5 1.3 72.6 3.5 0.4 0.9 0.9 224.8 1.6 1.3 0.6 0.5 0.3 33.7 6.2 22.3 0.9 0.1 5094.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.2 10.7 246.5 0.0 2.7 0.5 2.0 29.3 0.7 12.8 0.0 0.0 0.8 0.1 116.6 1.0 0.3 0.1 0.5 0.0 14.9 0.5 0.4 0.2 0.5 0.0 0.0 0.0 0.0 9.7 0.1 0.3 0.4 6071.6 19.8 0.0 0.0 0.0 0.0 87.0 0.2 0.6 24.8 0.0 0.0 0.2 0.2 0.9 0.6 0.3 0.8 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.7 0.3 0.4 1.0 0.4 0.6 2.1 0.5 0.9 1.3 0.9 0.7 3.2 5.5 0.0 0.7 44.1 46.8 389.5 274.3 0.0 0.1 1.5 0.4 2.8 150.1 0.0 0.0 0.0 0.0 5.1 0.0 1.4 1.5 12.4 0.2 1.3 1.8 0.0 0.1 0.5 0.0 1.6 437.9 0.8 2.5 0.3 1.4 3.2 0.2 0.0 0.0 4.8 83.4 0.3 1.8 5.2 0.9 1.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 9.5 4.7 1.9 3.2 5.8 3.4 5.0 412.7 0.2 0.0 1.7 20.1 1.7 8.6 342.2 32.0 0.0 0.5 0.2 8.4 64.3 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 33.9;HaCaT: 24.9;SuSa: 38.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.7 33.9 0.0 0.0 0.0 0.0 24.9 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 138 "intestine: 141.2" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.7;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 4.8" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" NA NA 130000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 141.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 128.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 290.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.8;placenta: 34.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 12.8;Glandular and luminal cells: 5.0;Syncytiotrophoblasts: 6.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 381.0;SiHa: 103.6" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 34.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 42.9 0.0 0.1 0.0 0.1 381.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 103.6 35.3 0.0 3.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 6.7 0.1 0.2 0.0 0.0 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 AMDHD1 MGC35366 ENSG00000139344 "Amidohydrolase domain containing 1" Q96NU7 12 95943331-95968720 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Histidine metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 60.7;skeletal muscle: 27.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 132.5" "Cancer enriched" "Detected in many" 14 "liver cancer: 23.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 46.6;HMC-1: 47.7;Karpas-707: 61.2;SiHa: 40.5;SK-BR-3: 46.1;U-266/70: 49.1;U-266/84: 62.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039720, HPA040149" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" No NA 1400000 "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Nucleoplasm, Plasma membrane" "HPA039720: AB_10672967, HPA040149: " "unprognostic (4.81e-2)" "unprognostic (2.91e-1)" "unprognostic (1.53e-1)" "unprognostic (2.09e-2)" "unprognostic (1.80e-2)" "unprognostic (2.88e-2)" "unprognostic (2.33e-2)" "unprognostic (6.62e-3)" "unprognostic (1.06e-1)" "unprognostic (7.01e-2)" "unprognostic (3.35e-3)" "unprognostic (1.17e-1)" "unprognostic (4.63e-3)" "unprognostic (3.98e-2)" "unprognostic (1.70e-1)" "unprognostic (4.08e-3)" "unprognostic (2.61e-1)" 1.8 11.7 8.2 6.5 11.2 6.1 0.4 5.5 11.8 0.3 6.9 1.4 5.1 3.0 0.4 2.6 0.7 1.7 1.7 7.6 6.9 5.8 60.7 2.3 4.4 15.5 8.6 1.4 3.3 0.7 0.5 2.0 9.5 2.8 0.2 1.8 2.0 0.2 27.3 5.8 5.0 0.6 2.7 5.9 4.8 13.1 8.0 0.6 0.9 0.9 0.4 0.3 0.2 15.4 46.6 9.5 0.8 5.8 0.0 0.0 10.0 1.5 0.5 0.7 1.4 3.9 5.8 4.0 4.2 0.0 2.6 8.2 0.3 0.0 0.3 16.0 1.7 4.2 7.9 9.4 0.0 5.9 47.7 0.0 0.4 0.8 0.1 0.2 0.3 3.9 2.7 61.2 0.0 6.8 3.7 10.8 4.4 1.8 2.2 7.8 0.3 5.3 0.0 4.3 4.9 6.9 40.5 46.1 5.2 0.2 4.6 8.4 0.0 5.8 19.1 8.0 5.4 49.1 62.8 6.3 3.8 12.2 6.9 0.2 0.6 1.7 0.5 0.6 0.4 0.6 0.2 0.6 0.5 0.3 0.3 0.4 0.4 2.3 1.8 0.2 0.1 0.5 8.2 11.2 5.5 11.8 7.6 6.9 15.5 8.6 9.5 2.7 8.0 15.4 1.1 0.0 0.5 0.3 2.0 0.4 0.2 0.0 0.0 0.1 1.1 1.0 0.6 1.5 0.6 3.7 0.0 0.9 1.7 0.0 3.9 0.2 0.9 0.1 0.0 0.8 1.8 8.0 0.7 1.1 0.1 0.1 0.0 0.0 0.0 0.2 8.6 132.5 4.4 1.7 0.3 0.1 0.0 5.7 1.3 0.1 0.3 1.8 3.6 0.0 0.7 1.8 2.1 4.0 2.0 0.2 0.0 0.0 0.7 0.0 0.4 31.0 0.0 0.0 0.0 0.8 0.0 1.5 1.9 0.0 0.3 0.3 1.4 0.3 0.4 0.1 AMER1 "FAM123B, FLJ39827, RP11-403E24.2, WTX" ENSG00000184675 "APC membrane recruitment protein 1" Q5JTC6 X 64185117-64205708 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "tongue: 15.3" "Cell type enhanced" "Detected in many" "Sertoli cells: 6.6;Theca cells: 6.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065214, HPA065265" Approved Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Nuclear bodies" "Vesicles, Plasma membrane" "HPA065214: AB_2685435, HPA065265: AB_2685450" "unprognostic (1.56e-2)" "unprognostic (8.85e-2)" "unprognostic (6.86e-2)" "unprognostic (2.74e-1)" "unprognostic (2.12e-2)" "unprognostic (1.86e-1)" "unprognostic (3.57e-2)" "unprognostic (1.48e-1)" "unprognostic (8.02e-2)" "unprognostic (1.75e-1)" "unprognostic (6.31e-2)" "unprognostic (3.43e-1)" "unprognostic (4.69e-4)" "unprognostic (1.26e-1)" "unprognostic (1.13e-1)" "unprognostic (6.19e-2)" "unprognostic (2.89e-1)" 1.1 1.4 1.6 1.3 1.5 1.2 1.3 1.8 1.6 1.9 0.1 1.5 1.5 1.9 4.0 2.8 2.2 1.0 1.3 1.0 1.6 1.8 2.1 1.2 1.2 1.5 1.4 6.3 2.0 1.6 0.7 0.8 1.5 1.7 1.3 1.3 2.2 2.2 4.1 2.2 1.3 2.8 0.7 1.3 1.6 0.4 1.9 1.6 1.4 15.3 1.6 1.3 1.3 1.0 3.1 2.2 5.8 4.6 2.2 2.1 4.7 1.4 1.2 2.1 1.3 7.3 1.1 5.9 1.8 3.0 1.6 4.3 12.5 4.1 2.0 2.5 2.5 3.7 4.9 4.9 1.6 7.7 0.9 3.0 5.3 1.6 3.2 1.7 1.2 4.6 5.6 5.9 1.1 3.7 5.2 4.0 15.6 4.0 4.4 11.7 9.4 4.3 0.9 1.0 2.6 3.9 3.7 5.0 1.9 4.8 1.6 2.1 0.8 2.5 5.8 6.7 1.9 3.0 2.2 4.4 1.2 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 1.5 1.8 1.6 1.0 1.6 1.5 1.4 1.5 0.7 1.9 1.0 0.9 0.0 0.0 1.0 1.5 2.2 0.6 0.9 2.8 5.0 1.7 1.5 2.6 4.3 0.3 0.0 2.1 1.1 3.4 1.1 0.0 1.2 0.1 3.3 2.6 1.5 1.2 0.8 0.8 1.6 0.8 1.8 3.6 2.0 0.0 3.9 1.4 2.6 0.4 0.0 1.3 1.0 0.0 1.0 0.3 0.2 2.5 0.5 1.8 1.0 1.2 0.2 0.0 1.0 0.6 0.7 0.5 4.1 2.4 1.2 0.8 0.8 0.0 1.0 6.6 2.3 4.4 0.0 0.2 3.6 2.6 0.7 0.9 6.4 1.6 0.7 AMER2 "FAM123A, FLJ25477" ENSG00000165566 "APC membrane recruitment protein 2" Q8N7J2 13 25161679-25172288 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 114.8" "Cell type enhanced" "Detected in some" "Astrocytes: 99.3;Bipolar cells: 105.5;Cone photoreceptor cells: 81.3;Horizontal cells: 153.1;Muller glia cells: 313.0;Oligodendrocytes: 337.1;Rod photoreceptor cells: 112.1" "Cancer enriched" "Detected in single" 24 "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 3.3;SCLC-21H: 2.3;SuSa: 2.3;U-266/70: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039458 Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA039458: AB_10795677" "unprognostic (1.69e-2)" "unprognostic (4.13e-2)" "unprognostic (7.43e-3)" "unprognostic (2.32e-1)" "unprognostic (3.00e-3)" "unprognostic (5.00e-3)" "unprognostic (7.28e-2)" "unprognostic (2.34e-2)" "unprognostic (5.90e-4)" "unprognostic (1.60e-2)" "unprognostic (1.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (1.34e-1)" 0.2 0.1 36.7 0.0 72.0 0.0 0.0 37.9 52.2 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 41.2 37.7 0.0 0.0 0.1 0.0 58.9 49.1 0.0 0.0 0.0 4.1 0.0 41.9 0.1 0.0 25.8 0.0 0.2 0.2 0.1 0.0 0.0 36.8 0.0 0.0 1.2 49.1 0.0 0.0 0.0 0.0 0.0 0.0 114.8 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.7 72.0 37.9 52.2 41.2 37.7 58.9 49.1 41.9 36.8 49.1 114.8 0.0 0.0 0.0 99.3 0.1 0.1 0.0 0.0 0.0 105.5 0.1 0.1 1.1 0.0 0.0 0.0 81.3 0.1 0.0 0.1 0.0 0.0 2.3 0.0 0.6 0.8 0.0 0.0 21.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 153.1 24.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.8 4.7 0.0 313.0 0.0 28.6 337.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 112.1 0.0 0.2 0.0 2.8 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 AMIGO2 "ALI1, DEGA" ENSG00000139211 "Adhesion molecule with Ig like domain 2" Q86SJ2 12 47075707-47079959 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 62.6;Enteroendocrine cells: 60.4;Glandular and luminal cells: 72.8;Granulosa cells: 76.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 192.0;fHDF/TERT166: 183.2;hTERT-RPE1: 312.2;LHCN-M2: 179.2;RT4: 251.9;U-2 OS: 149.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054004, HPA059601" Uncertain Approved "Golgi apparatus,Plasma membrane,Cytosol" NA Yes 390000 "Cluster 32: T-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Plasma membrane" Cytosol "HPA054004: AB_2682339, HPA059601: AB_2684078" "unprognostic (2.63e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" "unprognostic (3.91e-2)" "unprognostic (3.86e-1)" "unprognostic (1.07e-2)" "unprognostic (3.65e-2)" "unprognostic (1.67e-1)" "unprognostic (3.17e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.80e-4)" "unprognostic (2.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.16e-2)" "unprognostic (2.95e-1)" "unprognostic (7.47e-2)" "unprognostic (2.29e-3)" 10.8 19.8 4.5 7.0 4.9 3.5 22.8 3.6 5.4 20.3 2.3 39.4 3.3 30.7 7.9 4.0 36.4 19.3 5.6 3.2 8.8 7.7 4.6 20.0 12.4 9.1 37.9 28.7 3.6 6.4 5.3 13.2 19.6 11.3 9.0 25.7 4.5 11.0 1.1 4.4 12.6 34.3 4.3 17.4 5.5 10.7 13.1 2.8 4.2 2.2 7.6 22.6 14.3 3.9 44.4 105.5 6.3 0.2 2.5 0.2 17.2 14.8 39.3 4.7 3.8 0.3 192.0 0.0 47.6 183.2 117.0 64.8 0.0 117.6 5.5 8.6 0.7 0.0 11.0 0.1 3.8 1.2 1.7 0.9 20.1 122.6 59.5 312.2 15.0 0.9 8.5 0.0 179.2 2.1 3.6 0.1 4.5 21.2 27.1 0.3 46.5 0.1 52.3 251.9 18.8 0.0 76.2 9.0 0.5 3.4 11.2 1.0 4.1 2.6 149.9 1.7 121.3 1.9 0.4 0.2 10.0 3.4 2.8 0.0 0.1 0.0 4.4 0.2 6.0 3.7 6.8 6.9 0.7 1.6 15.3 12.1 0.1 8.6 0.0 8.8 4.4 4.7 4.5 4.9 3.6 5.4 3.2 8.8 9.1 37.9 19.6 4.3 13.1 3.9 7.2 9.6 3.1 1.0 3.6 2.4 13.1 39.4 15.4 62.6 10.8 37.7 1.6 1.5 4.9 1.8 0.0 1.0 12.4 0.4 1.9 5.3 1.4 31.5 6.0 12.7 60.4 5.7 2.6 19.3 28.1 11.1 0.5 72.8 7.0 76.8 32.2 1.2 4.8 0.0 0.2 3.1 2.0 3.5 1.1 2.3 2.5 7.2 1.8 1.9 5.3 15.6 2.1 0.0 0.1 40.4 1.5 0.7 3.8 10.7 0.0 0.1 2.9 4.9 0.0 3.2 27.7 0.7 2.4 2.5 0.4 8.5 7.6 12.8 0.3 33.9 AMOT KIAA1071 ENSG00000126016 Angiomotin Q4VCS5 X 112774503-112840889 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 145.6;tongue: 53.5" "Cell type enhanced" "Detected in many" "Astrocytes: 57.5;Collecting duct cells: 29.5;Cytotrophoblasts: 46.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 22.5;HAP1: 25.1;OE19: 21.2;SuSa: 34.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067290, HPA067853" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Cell Junctions" Nucleoplasm "HPA067290: AB_2685819, HPA067853: AB_2732773" "unprognostic (1.08e-2)" "unprognostic (5.51e-2)" "unprognostic (2.38e-2)" "unprognostic (3.36e-1)" "unprognostic (3.20e-1)" "unprognostic (8.95e-2)" "unprognostic (3.82e-2)" "prognostic favorable (3.94e-4)" "unprognostic (4.46e-2)" "unprognostic (3.79e-1)" "unprognostic (2.17e-1)" "unprognostic (5.60e-2)" "prognostic favorable (4.21e-9)" "unprognostic (9.54e-2)" "unprognostic (2.59e-2)" "unprognostic (4.50e-2)" "unprognostic (6.44e-2)" 4.3 1.6 29.0 1.3 24.7 0.3 6.5 23.4 21.9 9.2 0.6 3.5 2.9 4.9 145.6 4.0 12.2 2.8 4.0 23.7 31.6 10.4 2.1 2.7 0.8 32.8 34.4 5.7 2.3 14.3 7.2 20.7 24.1 6.3 4.3 1.7 6.9 25.7 39.0 2.3 3.7 3.2 20.6 1.5 3.0 2.3 36.4 4.4 3.8 53.5 1.0 2.8 4.1 18.2 4.3 0.0 22.5 1.0 0.5 0.5 8.8 0.7 0.0 0.0 0.0 10.5 0.8 0.5 4.7 3.5 0.0 8.4 25.1 0.0 0.0 0.0 6.3 0.0 0.0 0.2 0.2 0.0 1.1 0.2 0.0 5.1 0.6 4.9 0.2 0.4 0.0 0.0 0.6 0.4 6.8 0.3 10.5 21.2 0.1 8.4 6.6 0.1 11.2 11.0 0.0 8.0 0.1 0.0 9.8 34.9 0.8 0.2 0.1 2.9 6.8 0.0 9.4 0.7 0.0 0.0 1.0 0.1 6.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 29.0 24.7 23.4 21.9 23.7 31.6 32.8 34.4 24.1 20.6 36.4 18.2 2.2 3.2 2.0 57.5 0.9 1.8 2.7 2.5 2.8 1.1 9.7 6.9 2.0 1.5 7.2 29.5 0.0 46.2 1.1 4.9 1.9 5.1 0.2 7.2 6.3 3.7 15.8 0.4 8.9 1.9 3.8 7.2 4.1 7.1 0.0 1.5 4.2 4.0 6.2 0.0 2.0 7.2 6.1 1.6 2.1 0.5 6.8 1.0 3.6 17.8 1.7 4.9 4.1 2.0 3.5 3.2 5.6 6.4 0.0 6.6 4.7 16.8 10.1 0.5 6.6 3.9 4.0 0.4 3.2 3.0 1.1 15.9 0.9 0.8 7.3 2.5 AMOTL1 JEAP ENSG00000166025 "Angiomotin like 1" Q8IY63 11 94706431-94876748 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 112.0" "Cell type enhanced" "Detected in many" "Early spermatids: 127.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 111.4;WM-115: 105.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001196 Approved Approved "Cell Junctions,Cytosol" NA NA 59000 "Cluster 24: B-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 29: Early spermatids - Spermatogenesis" Cytosol "Cell Junctions" "HPA001196: AB_1078147" "unprognostic (2.21e-1)" "unprognostic (5.25e-2)" "unprognostic (4.23e-2)" "unprognostic (5.43e-2)" "unprognostic (7.58e-2)" "unprognostic (3.29e-2)" "unprognostic (1.05e-1)" "unprognostic (2.40e-1)" "unprognostic (2.09e-1)" "unprognostic (7.97e-2)" "unprognostic (1.85e-1)" "unprognostic (5.95e-2)" "prognostic favorable (5.03e-6)" "unprognostic (7.47e-3)" "unprognostic (1.39e-1)" "unprognostic (1.68e-2)" "unprognostic (1.29e-2)" 15.4 10.3 15.1 7.6 9.8 1.7 15.0 7.8 7.2 11.7 8.7 36.5 4.5 14.2 5.9 30.4 13.3 13.3 19.1 12.2 12.4 6.4 7.8 15.8 3.5 12.0 28.8 4.8 15.6 13.8 14.1 24.1 13.2 32.4 7.3 6.6 10.9 23.1 112.0 21.7 8.4 20.5 7.3 9.2 12.4 11.7 30.4 27.9 9.7 71.7 9.7 27.5 14.0 6.2 57.1 16.0 41.9 0.0 44.1 38.1 19.9 31.0 53.7 13.9 16.2 29.7 1.5 2.7 14.9 42.2 11.4 72.4 20.1 111.4 14.6 4.6 15.4 30.7 16.2 0.1 10.2 6.8 0.2 22.7 67.3 47.7 78.9 35.9 29.3 11.9 79.0 2.9 33.1 16.6 21.3 4.1 6.3 0.1 10.5 0.0 76.2 4.9 19.4 23.6 31.7 38.3 2.0 42.4 11.2 28.1 2.2 9.6 27.1 38.0 27.6 0.8 21.6 1.5 0.0 16.0 10.6 0.1 105.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.1 15.1 9.8 7.8 7.2 12.2 12.4 12.0 28.8 13.2 7.3 30.4 6.2 28.4 35.3 35.0 17.0 0.8 35.4 19.7 11.7 29.0 4.7 6.9 14.9 51.0 10.0 10.1 7.3 4.2 30.1 1.0 0.0 0.0 17.3 127.0 22.3 12.7 31.1 0.0 6.3 26.8 17.0 15.6 30.9 0.5 27.4 2.5 4.9 36.4 17.0 4.9 15.2 61.3 0.0 4.1 4.0 10.0 62.9 8.1 3.2 10.6 46.9 1.4 14.4 0.0 20.6 1.4 10.8 0.0 12.4 0.7 19.4 0.0 4.0 4.2 1.1 13.1 32.7 30.2 16.7 11.4 21.7 26.9 27.9 1.4 3.4 0.0 8.4 AMOTL2 LCCP ENSG00000114019 "Angiomotin like 2" Q9Y2J4 3 134355347-134375479 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 89.2;Suprabasal keratinocytes: 130.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 259.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063027 Approved "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA063027: AB_2684924" "unprognostic (2.23e-1)" "unprognostic (2.55e-2)" "unprognostic (7.01e-3)" "prognostic unfavorable (1.94e-4)" "unprognostic (6.09e-2)" "unprognostic (1.57e-2)" "unprognostic (9.84e-2)" "unprognostic (4.40e-2)" "unprognostic (2.32e-1)" "unprognostic (3.02e-1)" "unprognostic (2.85e-2)" "unprognostic (1.49e-1)" "unprognostic (8.09e-2)" "unprognostic (3.59e-1)" "unprognostic (7.67e-2)" "unprognostic (3.85e-1)" "unprognostic (1.17e-2)" 80.0 11.1 24.1 7.1 42.5 0.2 55.9 26.0 32.7 34.4 32.0 28.3 7.7 44.3 9.1 37.1 37.5 22.8 25.9 17.5 22.9 25.6 17.2 33.4 11.9 40.8 35.0 21.5 27.2 9.6 5.7 33.6 33.6 24.6 5.5 5.4 25.1 15.8 16.8 39.7 15.8 16.7 21.6 20.5 23.1 4.2 36.3 4.3 29.5 15.9 7.2 29.1 33.3 70.2 99.1 43.1 29.6 30.9 30.3 37.3 259.9 97.5 54.8 87.6 43.0 132.5 30.3 0.0 119.9 69.4 50.0 72.2 19.4 26.3 39.9 0.2 2.2 0.2 22.7 14.4 56.8 0.2 0.2 53.7 79.5 34.5 39.7 35.1 42.3 0.9 0.7 0.2 59.2 31.7 0.3 0.3 37.9 21.4 16.3 0.2 37.4 0.3 56.4 22.7 4.5 11.7 73.8 94.3 68.8 66.8 88.2 0.8 72.4 59.5 53.2 41.7 59.7 0.1 0.3 0.4 22.1 0.1 68.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.1 42.5 26.0 32.7 17.5 22.9 40.8 35.0 33.6 21.6 36.3 70.2 24.0 60.9 17.3 2.6 0.2 72.9 18.4 15.4 30.1 10.4 29.2 21.5 15.6 52.9 16.4 18.4 18.8 30.4 1.1 6.5 17.6 27.5 4.0 59.7 29.1 30.1 12.5 0.0 4.5 13.1 29.9 30.3 20.4 89.2 1.3 34.1 51.8 25.8 3.0 1.7 5.8 3.6 6.1 1.6 7.8 10.9 35.8 1.7 14.2 9.4 0.0 12.1 0.0 18.6 56.9 52.8 4.2 19.9 0.0 30.0 10.6 19.3 16.2 5.1 13.1 12.1 46.1 0.2 0.6 25.3 130.1 24.8 2.6 8.7 4.5 37.3 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 490.2;Excitatory neurons: 859.2;Inhibitory neurons: 881.3;Oligodendrocyte precursor cells: 592.6;Oligodendrocytes: 1579.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 50.3;SK-BR-3: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" 6.3 6.7 45.5 6.5 86.5 2.1 21.5 144.9 82.3 12.0 0.0 26.0 39.3 23.0 125.2 16.9 19.1 21.5 81.1 60.8 86.1 95.4 16.6 24.6 6.1 82.7 61.3 11.6 11.2 131.8 14.5 15.6 97.0 20.0 20.9 123.2 42.6 40.5 80.5 39.9 27.2 13.2 21.2 10.8 15.5 8.0 87.3 9.1 41.6 94.1 7.4 10.8 14.1 114.4 8.7 4.9 30.3 0.4 0.0 1.8 23.3 0.6 0.4 0.1 0.6 22.2 16.6 0.5 9.8 0.6 0.9 12.1 16.4 14.9 0.5 0.5 11.0 0.2 9.7 0.1 6.2 0.1 0.4 14.6 9.3 7.8 0.4 26.1 3.6 0.0 4.3 20.6 6.9 29.0 0.2 1.0 13.8 23.3 26.6 0.1 21.7 4.3 5.4 50.3 15.6 2.8 0.6 49.4 0.0 33.6 28.7 0.1 10.0 0.9 2.9 13.3 1.5 0.9 0.2 0.2 5.5 0.2 18.9 1.6 0.2 0.5 2.7 0.2 2.4 4.1 4.6 1.5 0.1 1.1 5.0 1.2 0.7 1.5 0.3 2.5 0.8 1.0 45.5 86.5 144.9 82.3 60.8 86.1 82.7 61.3 97.0 21.2 87.3 114.4 0.9 44.8 174.3 20.2 14.5 19.1 21.9 17.8 38.7 490.2 26.8 20.6 189.3 12.8 42.5 53.3 225.2 38.8 3.4 62.9 19.6 10.6 28.3 139.8 26.2 3.9 30.6 0.0 859.2 8.6 9.9 13.2 15.8 153.3 12.6 66.9 7.9 0.5 4.7 43.7 881.3 12.1 14.2 4.8 1.4 11.5 28.0 3.3 8.8 23.4 4.4 41.4 0.0 592.6 1579.5 4.8 41.8 5.7 3.4 12.2 62.5 51.3 66.7 216.6 0.0 30.2 11.7 1.1 2.3 35.9 18.2 25.0 18.5 4.5 17.8 18.4 ANKEF1 "ANKRD5, dJ839B4.6, FLJ21669" ENSG00000132623 "Ankyrin repeat and EF-hand domain containing 1" Q9NU02 20 9986126-10058303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 14.0;testis: 14.6" "Group enriched" "Detected in many" 21 "Early spermatids: 323.1;Late spermatids: 383.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "U-266/84: 14.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA041151 Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 16: U-266 - Nucleosome" "Cluster 34: Spermatids - Unknown function" "Nucleoli fibrillar center, Plasma membrane, Cytosol" "HPA041151: AB_10796569" "unprognostic (4.72e-2)" "unprognostic (9.86e-2)" "unprognostic (2.31e-2)" "unprognostic (2.09e-1)" "unprognostic (5.38e-4)" "unprognostic (2.54e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (1.81e-4)" "unprognostic (3.21e-2)" "unprognostic (1.12e-1)" "unprognostic (3.28e-1)" "unprognostic (6.73e-2)" "prognostic favorable (4.44e-4)" "unprognostic (3.90e-2)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.58e-4)" "unprognostic (3.11e-1)" 2.4 1.4 1.1 1.5 1.1 0.6 3.1 2.7 1.4 2.2 2.8 2.5 2.5 1.0 1.0 2.5 4.0 2.2 1.0 0.9 1.7 2.5 4.0 1.7 1.2 1.4 1.3 2.2 14.0 4.3 2.2 0.7 1.4 1.9 2.3 5.3 2.6 2.1 0.6 2.8 2.4 0.7 0.9 1.2 3.7 14.6 1.6 1.7 5.7 0.6 1.8 1.6 1.3 0.9 9.0 8.7 0.9 2.1 2.2 1.5 5.9 1.3 0.1 1.6 0.8 5.1 7.2 0.1 2.4 0.3 9.7 7.1 2.3 9.0 1.9 0.0 1.4 1.1 2.2 5.3 1.0 0.9 0.2 3.9 9.8 1.5 1.4 4.0 1.4 3.2 3.4 6.1 0.4 2.4 1.4 0.0 4.4 11.2 2.4 0.0 0.1 5.6 5.3 5.5 6.5 3.1 3.8 8.7 0.0 3.2 7.2 0.8 0.9 1.1 1.4 0.1 1.4 7.0 14.2 1.3 2.4 0.4 1.2 0.0 0.0 0.0 0.7 0.0 1.1 0.5 0.7 0.5 0.0 0.4 1.0 0.6 0.1 0.5 0.0 0.5 0.7 0.2 1.1 1.1 2.7 1.4 0.9 1.7 1.4 1.3 1.4 0.9 1.6 0.9 0.5 3.2 6.7 1.3 2.0 0.3 2.3 1.6 3.4 1.7 3.4 1.8 1.8 2.8 2.0 7.3 0.0 2.2 1.2 2.7 1.9 4.5 323.1 6.7 1.0 1.8 5.3 0.4 1.1 6.3 2.0 0.9 10.7 2.8 1.3 0.7 0.7 9.1 1.3 3.3 2.8 3.8 2.0 0.3 0.6 383.0 3.4 1.4 0.0 1.0 0.0 0.8 3.1 0.5 0.4 5.3 4.2 4.1 4.8 1.9 3.3 2.8 16.2 4.9 0.0 0.7 0.3 5.1 3.4 8.6 0.3 1.5 2.6 1.1 3.7 1.5 ANKFN1 FLJ38335 ENSG00000153930 "Ankyrin repeat and fibronectin type III domain containing 1" Q8N957 17 55882301-56511659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;cervix: 9.2;fallopian tube: 5.3" "Cell type enhanced" "Detected in some" "Astrocytes: 138.4;Excitatory neurons: 27.2;Inhibitory neurons: 86.6;Oligodendrocyte precursor cells: 70.9;Respiratory ciliated cells: 31.0" "Cancer enhanced" "Detected in some" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.8;MOLT-4: 15.4;T-47d: 5.0;U-2197: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021566, HPA022538, HPA048953" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane" "HPA021566: AB_1844828, HPA022538: AB_1844829, HPA048953: " "unprognostic (6.64e-2)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.38e-5)" "unprognostic (2.39e-1)" "unprognostic (2.31e-3)" "unprognostic (3.84e-2)" "unprognostic (1.68e-1)" "unprognostic (3.31e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-2)" "unprognostic (6.81e-3)" "unprognostic (3.44e-8)" "unprognostic (1.24e-1)" "unprognostic (1.69e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-2)" 0.7 0.2 5.3 0.0 3.6 0.0 0.3 3.6 1.8 9.2 0.6 0.1 0.1 0.1 0.9 0.2 5.3 0.2 0.0 3.1 8.4 0.1 0.0 0.7 0.0 7.5 11.3 0.0 0.0 0.0 0.3 0.8 6.2 0.2 0.1 0.2 0.2 0.1 0.0 2.2 0.1 0.0 7.7 0.0 0.3 1.7 9.7 0.6 0.1 0.0 0.0 1.0 0.9 3.0 0.0 0.0 0.1 0.0 1.1 0.1 0.3 0.0 2.5 0.1 0.2 0.0 0.0 0.2 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.1 0.4 15.4 0.0 0.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 1.5 0.0 0.2 0.0 5.0 0.0 0.0 0.0 0.3 4.8 0.0 1.3 0.2 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 3.6 3.6 1.8 3.1 8.4 7.5 11.3 6.2 7.7 9.7 3.0 0.0 0.0 1.1 138.4 0.0 0.5 0.1 0.6 0.0 0.0 0.3 0.1 0.6 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 18.7 16.9 1.2 0.3 0.0 0.0 27.2 0.0 0.9 1.1 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 86.6 2.4 0.0 0.0 0.7 8.6 0.6 0.0 1.8 11.2 0.0 0.3 0.0 70.9 3.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 31.0 0.1 6.6 0.0 0.5 6.4 2.7 0.0 0.4 2.9 0.0 0.0 0.1 1.4 ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92245974-92401383 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 182.5;Inhibitory neurons: 218.0;Oligodendrocyte precursor cells: 176.5;Oligodendrocytes: 590.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA019358: AB_1844831, HPA021780: AB_2670819" "unprognostic (1.77e-1)" "unprognostic (5.96e-3)" "unprognostic (1.23e-1)" "unprognostic (4.97e-3)" "unprognostic (2.75e-1)" "unprognostic (7.67e-2)" "unprognostic (4.88e-3)" "unprognostic (2.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.52e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.00e-1)" "unprognostic (3.00e-2)" "unprognostic (3.20e-1)" 12.6 10.6 28.4 10.0 56.8 6.9 12.3 21.2 42.0 12.6 0.0 12.9 11.1 12.0 15.9 11.8 9.8 14.9 10.2 19.0 54.6 25.6 10.6 11.0 13.2 32.9 32.4 12.6 12.2 23.9 7.5 12.7 34.5 10.0 12.8 9.9 13.9 11.2 7.7 14.4 12.0 13.6 14.0 12.4 11.7 20.8 36.3 14.5 17.2 9.9 11.7 13.2 9.0 85.5 35.7 20.9 18.7 27.3 32.0 34.9 19.2 27.1 30.0 25.4 34.0 15.8 52.0 20.0 23.4 39.7 66.8 16.5 16.5 28.1 38.0 35.1 14.0 13.1 23.7 12.1 22.0 18.8 26.5 23.1 22.8 31.0 38.2 34.6 28.7 17.4 16.9 41.8 30.0 27.5 39.6 17.0 19.6 23.9 23.7 14.6 22.8 21.9 26.6 30.7 25.5 29.4 39.2 41.8 22.4 34.8 17.5 10.2 26.2 48.5 40.2 55.3 27.8 26.7 52.3 25.4 27.7 21.9 56.2 1.4 0.4 1.2 0.9 0.7 0.7 1.7 0.9 1.3 0.4 2.0 0.7 1.0 0.2 1.2 0.6 1.6 1.9 0.4 28.4 56.8 21.2 42.0 19.0 54.6 32.9 32.4 34.5 14.0 36.3 85.5 24.1 25.6 30.4 97.6 21.8 18.6 17.5 16.4 13.1 20.8 25.6 20.2 33.4 24.3 22.3 27.6 18.8 13.4 27.8 20.7 1.9 21.5 52.8 21.5 37.2 22.4 41.9 8.8 182.5 19.2 25.2 25.9 14.3 27.0 26.6 47.4 27.8 15.1 13.5 30.3 218.0 24.8 10.2 22.2 16.1 61.1 33.2 20.4 17.8 87.1 20.6 27.3 34.0 176.5 590.8 33.5 11.8 40.6 23.4 26.5 20.8 37.3 18.8 16.2 19.7 34.8 26.1 70.9 50.4 20.3 22.7 14.0 22.7 31.2 21.7 21.9 ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.7;Urothelial cells: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003602: AB_1858349, HPA074838: " "unprognostic (4.43e-2)" "unprognostic (6.92e-2)" "unprognostic (7.97e-2)" "unprognostic (9.84e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.97e-6)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (4.76e-2)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (6.92e-3)" "unprognostic (2.09e-1)" 30.0 37.6 12.4 27.0 13.3 38.4 27.8 15.2 16.6 25.4 21.9 23.8 17.8 24.9 19.0 33.6 25.2 17.4 22.0 13.8 14.1 21.8 22.9 31.3 31.6 12.3 12.4 27.1 24.6 17.9 23.1 20.4 12.3 23.9 16.1 12.3 26.1 15.6 29.3 36.9 33.3 21.9 12.0 37.9 24.1 55.7 14.3 26.2 23.3 18.3 31.2 25.0 27.6 13.2 50.7 46.4 47.3 29.5 26.9 42.1 59.1 60.2 44.7 59.0 45.0 53.2 33.6 39.5 30.7 53.1 39.5 59.2 41.8 54.8 56.2 17.0 51.6 50.1 84.0 25.2 29.9 54.6 34.0 39.1 54.9 56.2 41.3 108.8 42.8 32.0 46.1 15.1 61.2 36.4 51.1 89.4 40.1 24.8 43.9 58.0 31.1 16.7 42.6 64.9 57.9 35.6 77.7 32.4 27.1 44.1 56.9 39.1 61.5 70.5 50.9 38.0 68.1 27.9 29.5 47.9 54.7 35.8 40.5 0.9 1.2 4.4 1.8 1.1 2.4 2.7 2.6 2.8 1.7 2.8 2.4 2.0 0.7 2.7 1.3 1.7 2.6 0.7 12.4 13.3 15.2 16.6 13.8 14.1 12.3 12.4 12.3 12.0 14.3 13.2 38.0 73.7 31.2 18.3 43.2 67.3 92.0 38.2 32.5 32.3 31.2 27.1 24.6 27.1 51.3 31.3 45.9 29.2 41.1 33.8 1.9 33.2 109.1 58.6 52.4 36.3 20.8 23.1 21.0 32.7 35.5 35.7 35.2 119.2 18.4 38.3 22.9 12.9 20.1 32.0 17.8 18.0 24.4 19.7 47.6 24.5 25.1 35.5 33.8 16.9 40.6 21.9 47.4 18.1 18.4 101.9 24.8 28.2 47.6 116.9 18.8 8.5 32.3 39.7 26.3 39.2 40.5 215.7 61.8 44.8 72.9 36.5 44.7 31.6 24.0 168.7 ANKRA2 ENSG00000164331 "Ankyrin repeat family A member 2" Q9H9E1 5 73552190-73565667 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003968, HPA065263" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA003968: , HPA065263: AB_2685449" "unprognostic (1.75e-1)" "unprognostic (5.78e-2)" "unprognostic (1.40e-1)" "unprognostic (1.86e-1)" "unprognostic (3.31e-1)" "unprognostic (3.89e-2)" "unprognostic (5.68e-2)" "unprognostic (6.19e-2)" "unprognostic (3.47e-2)" "unprognostic (1.09e-1)" "unprognostic (1.06e-2)" "unprognostic (1.79e-1)" "unprognostic (9.80e-3)" "unprognostic (3.36e-1)" "unprognostic (3.31e-1)" "unprognostic (6.65e-2)" "unprognostic (1.13e-3)" 7.8 11.3 4.6 5.7 5.1 14.0 10.1 5.7 5.4 9.4 5.2 8.9 9.6 12.4 13.1 7.5 11.4 9.7 8.2 4.2 5.1 5.9 10.8 7.0 9.9 5.0 4.9 14.1 8.3 8.0 7.5 10.0 5.3 12.4 10.4 9.9 10.9 8.4 7.6 9.1 9.6 8.3 5.1 8.8 10.0 6.7 5.2 10.0 14.3 6.6 8.1 7.4 7.7 6.2 6.6 4.5 6.6 7.5 12.3 19.3 20.6 9.0 13.2 7.6 11.0 1.4 9.4 6.2 7.0 8.8 7.3 4.5 3.1 15.4 10.9 11.9 5.5 5.4 3.6 6.5 9.6 3.1 9.3 19.8 21.0 9.1 9.2 13.6 8.7 6.7 5.3 9.9 8.6 3.8 5.6 8.5 3.9 2.5 3.7 3.5 7.1 8.7 5.6 8.2 9.0 6.9 6.9 5.3 11.0 10.2 8.2 5.0 11.2 3.0 3.4 4.9 6.3 19.7 15.1 5.3 7.5 5.1 8.8 19.9 5.1 11.2 7.6 4.5 9.3 9.9 8.9 10.7 4.6 8.0 13.3 12.4 8.4 7.3 7.8 5.3 11.5 6.8 4.6 5.1 5.7 5.4 4.2 5.1 5.0 4.9 5.3 5.1 5.2 6.2 10.7 3.2 11.5 10.4 23.5 15.8 30.1 29.8 26.2 26.2 20.7 15.9 8.9 31.5 22.7 18.4 10.4 26.3 27.1 16.0 27.4 14.1 1.3 18.1 11.0 12.8 24.1 21.5 10.0 16.6 22.2 13.8 10.7 13.4 19.0 18.8 15.7 23.8 10.5 23.5 12.9 22.6 36.7 18.5 6.7 2.2 32.6 11.1 12.4 16.9 15.1 16.2 17.5 21.1 22.3 16.9 20.0 29.0 14.6 25.7 21.5 18.0 21.4 21.2 26.3 11.3 17.8 25.6 15.9 16.0 12.4 48.8 20.4 16.3 17.0 36.8 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANKRD42 "FLJ37874, PPP1R79, SARP" ENSG00000137494 "Ankyrin repeat domain 42" Q8N9B4 11 83193712-83260694 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 37.2" "Cell type enhanced" "Detected in all" "Early spermatids: 170.5;Late spermatids: 63.2;Respiratory ciliated cells: 61.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039917 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039917: AB_10672894" "unprognostic (6.59e-2)" "unprognostic (9.00e-2)" "unprognostic (1.00e-1)" "unprognostic (1.31e-3)" "unprognostic (9.12e-2)" "unprognostic (3.78e-1)" "unprognostic (1.67e-2)" "unprognostic (1.03e-1)" "unprognostic (1.11e-1)" "unprognostic (2.11e-1)" "unprognostic (2.99e-2)" "unprognostic (1.59e-1)" "unprognostic (1.09e-2)" "unprognostic (3.10e-3)" "unprognostic (1.79e-1)" "unprognostic (4.25e-1)" "unprognostic (1.90e-1)" 5.2 13.3 8.0 5.2 8.9 9.0 6.0 4.3 11.8 7.4 15.8 5.8 5.2 6.0 19.7 4.8 15.8 7.6 5.3 11.6 14.3 11.1 4.7 6.6 3.8 10.0 9.2 8.7 5.9 12.3 13.1 3.9 7.9 7.2 4.2 17.8 6.0 7.4 2.7 5.5 4.9 5.3 7.6 4.5 6.2 37.2 10.7 2.8 11.8 2.2 4.1 7.3 5.5 8.2 5.6 9.7 4.7 9.5 14.3 15.0 4.1 11.4 8.8 6.7 4.1 5.9 6.8 2.2 14.1 10.3 13.4 11.9 5.0 7.8 5.5 3.2 3.7 4.0 14.5 4.0 10.0 11.6 9.0 8.9 8.8 17.0 8.9 12.3 7.0 4.0 12.0 2.0 9.8 7.9 1.7 12.2 3.9 8.8 6.1 2.7 6.5 2.8 21.8 6.6 3.7 4.9 14.9 9.2 2.9 6.1 13.9 6.2 10.2 10.2 7.1 37.1 5.4 2.9 7.1 4.5 7.9 6.7 4.3 5.7 2.6 3.2 2.9 3.0 1.9 5.0 2.5 2.9 3.5 3.8 1.2 2.0 2.0 4.4 8.0 1.4 1.1 1.7 8.0 8.9 4.3 11.8 11.6 14.3 10.0 9.2 7.9 7.6 10.7 8.2 7.6 9.6 16.0 7.5 8.5 11.2 21.5 6.5 4.0 3.9 11.9 9.8 7.8 8.6 8.0 7.3 39.6 3.1 7.1 5.2 9.8 7.7 170.5 53.1 21.9 8.5 3.0 2.1 33.3 6.7 3.3 13.0 7.7 15.4 13.9 7.8 9.3 4.8 5.0 1.7 27.3 3.1 12.2 7.2 9.9 63.2 8.7 8.8 7.2 7.5 7.3 7.4 2.1 4.5 2.9 5.7 4.9 10.5 4.7 10.6 5.8 14.8 61.6 22.4 13.1 16.6 9.0 55.5 17.3 4.7 15.3 5.5 9.1 14.5 3.9 11.5 ANKRD45 "CT117, FLJ45235" ENSG00000183831 "Ankyrin repeat domain 45" Q5TZF3 1 173608336-173669851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 6.7;choroid plexus: 14.3;fallopian tube: 12.7;parathyroid gland: 9.3;testis: 11.0" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Early spermatids: 48.8;Endometrial ciliated cells: 23.7;Late spermatids: 16.8;Respiratory ciliated cells: 31.8;Spermatocytes: 54.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 5.5;BJ hTERT+: 2.0;BJ hTERT+ SV40 Large T+ RasG12V: 2.6;GAMG: 1.9;HBF TERT88: 1.9;SH-SY5Y: 5.7" "HPA031655, HPA031656, HPA031657" Enhanced Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane, Centrosome" "HPA031655: AB_10610975, HPA031656: AB_10600331, HPA031657: AB_10602196" "unprognostic (1.93e-1)" "unprognostic (1.22e-1)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (1.29e-3)" "unprognostic (4.02e-1)" "unprognostic (3.57e-2)" "unprognostic (2.69e-3)" "unprognostic (4.15e-2)" "unprognostic (6.93e-2)" "unprognostic (2.45e-1)" "unprognostic (3.05e-2)" "unprognostic (4.49e-2)" "unprognostic (8.80e-3)" "unprognostic (2.91e-2)" "unprognostic (5.15e-2)" "unprognostic (1.61e-1)" 0.2 0.6 2.8 0.0 5.4 0.2 0.1 1.9 2.5 1.3 14.3 0.2 0.0 1.6 0.7 0.0 12.7 0.3 0.4 4.3 2.8 1.3 0.0 1.2 0.0 5.2 6.7 0.7 0.3 9.3 1.8 0.0 3.9 0.8 0.1 2.6 0.0 0.3 0.2 0.0 0.0 1.1 3.3 0.4 0.1 11.0 3.8 0.2 0.5 0.0 0.0 0.1 0.1 4.0 0.0 0.0 5.5 0.0 0.0 0.3 0.1 0.0 2.0 1.7 2.6 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 5.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 1.2 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 2.8 5.4 1.9 2.5 4.3 2.8 5.2 6.7 3.9 3.3 3.8 4.0 0.2 0.0 1.7 12.4 0.0 0.3 0.3 1.1 0.0 0.7 0.1 0.4 0.9 0.0 1.5 5.5 37.5 0.2 0.0 0.3 1.9 0.6 48.8 23.7 1.3 1.3 0.0 0.0 4.6 0.5 0.3 0.4 0.0 0.6 0.0 1.1 3.3 0.0 0.1 0.0 4.1 0.0 6.1 0.0 0.0 16.8 1.8 0.2 0.0 2.8 0.0 3.3 0.0 0.5 3.2 0.1 0.0 0.4 0.0 0.2 0.0 0.4 31.8 1.7 0.0 0.1 0.8 54.9 7.9 0.0 0.0 0.1 0.0 5.5 0.4 0.1 ANKS1B "AIDA-1, ANKS2, cajalin-2, EB-1" ENSG00000185046 "Ankyrin repeat and sterile alpha motif domain containing 1B" Q7Z6G8 12 98726457-99984654 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 77.0;skeletal muscle: 34.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 2224.0;Inhibitory neurons: 1545.5;Oligodendrocyte precursor cells: 1318.0;Oligodendrocytes: 1000.1" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "AF22: 10.3;ASC TERT1: 5.8;SCLC-21H: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078230 Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA078230: " "unprognostic (5.50e-2)" "unprognostic (3.26e-2)" "unprognostic (1.01e-2)" "unprognostic (6.87e-3)" "unprognostic (1.18e-1)" "unprognostic (1.14e-4)" "unprognostic (7.94e-2)" "unprognostic (2.47e-1)" "unprognostic (1.84e-2)" "unprognostic (3.03e-2)" "unprognostic (4.97e-4)" "unprognostic (2.81e-1)" "unprognostic (1.14e-3)" "unprognostic (1.64e-2)" "unprognostic (1.15e-2)" "unprognostic (1.09e-2)" "unprognostic (3.75e-3)" 1.6 3.6 36.2 0.7 50.4 0.1 2.7 40.2 77.0 2.9 0.0 4.0 0.5 2.3 1.4 2.9 3.6 1.2 1.4 51.8 5.2 4.6 1.1 1.0 0.6 0.0 7.9 8.9 1.1 0.8 10.1 1.8 2.0 3.1 1.0 6.2 3.1 2.7 34.2 1.0 1.1 2.3 0.4 1.1 1.4 7.6 13.8 1.0 5.6 1.8 0.3 2.1 1.7 71.6 0.2 2.2 10.3 2.4 4.0 5.8 0.5 0.0 1.1 0.7 0.8 0.2 0.7 0.8 0.4 1.5 3.1 0.4 0.1 0.0 0.2 1.2 0.7 0.1 0.7 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.7 0.1 0.6 0.4 0.5 2.9 0.0 1.9 0.7 0.0 0.2 0.1 0.0 11.1 1.1 0.9 3.2 1.2 0.8 3.7 0.1 0.1 0.9 0.9 0.6 0.6 0.0 0.7 0.5 0.9 0.2 0.9 3.7 0.6 1.1 0.7 1.0 1.1 0.9 1.3 0.7 0.6 0.9 1.0 1.0 1.9 1.5 1.6 1.2 4.3 0.6 36.2 50.4 40.2 77.0 51.8 5.2 0.0 7.9 2.0 0.4 13.8 71.6 0.5 3.2 3.9 228.8 0.8 1.1 1.1 0.2 4.6 32.9 6.3 2.4 2.4 0.0 1.3 9.2 18.8 0.4 0.5 0.0 0.0 0.5 142.2 2.6 0.8 0.8 0.0 0.0 2224.0 0.0 0.3 5.7 1.1 0.9 1.3 0.3 0.4 0.5 0.6 30.3 1545.5 0.0 0.0 0.0 1.9 92.0 1.2 0.4 5.4 84.3 0.2 1.7 1.0 1318.0 1000.1 0.0 1.1 6.0 0.3 0.5 0.0 5.0 3.1 3.4 6.6 12.1 1.8 31.8 3.9 2.6 1.4 0.8 2.1 0.5 0.1 0.6 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" 86.4 25.9 7.4 16.8 8.0 9.8 27.5 7.9 8.4 28.9 13.8 29.9 36.2 38.9 25.6 25.0 27.2 31.6 27.7 7.2 10.5 36.2 56.9 40.2 13.4 10.4 8.5 56.6 25.3 58.8 6.9 50.5 10.1 29.9 15.0 3.6 25.4 37.1 56.0 12.0 51.4 48.4 9.0 16.0 13.8 11.8 9.1 24.9 13.2 46.3 12.8 35.0 16.0 9.3 41.5 44.3 25.7 35.4 119.1 61.7 97.4 57.4 72.5 38.4 36.3 71.9 61.5 21.1 52.2 92.0 34.9 54.0 24.1 32.3 45.6 31.4 16.9 25.0 17.8 62.1 37.8 39.5 19.4 51.7 31.9 33.0 48.7 95.4 52.6 44.5 19.3 34.0 42.7 11.2 41.5 13.2 28.6 0.0 18.0 23.4 33.3 24.4 36.9 63.1 11.7 39.9 59.9 36.8 27.9 67.7 43.3 62.8 70.6 41.2 26.1 41.8 29.3 18.3 21.5 25.8 37.3 122.8 33.4 3.1 5.9 1.4 2.4 6.9 2.5 1.4 2.2 2.0 5.5 1.2 2.0 1.3 0.6 2.3 7.1 2.7 3.0 4.2 7.4 8.0 7.9 8.4 7.2 10.5 10.4 8.5 10.1 9.0 9.1 9.3 65.1 60.9 11.8 54.9 10.0 30.5 20.3 27.7 23.3 1.1 23.0 18.7 23.4 30.0 21.5 18.4 0.0 34.0 14.5 2.5 3.9 38.4 1.3 13.3 32.1 37.5 8.4 8.0 49.8 37.4 28.0 44.2 21.4 26.0 12.7 20.2 52.5 88.3 19.9 0.0 49.0 11.5 12.2 56.3 22.9 3.5 51.3 46.0 17.8 68.4 29.1 8.2 15.5 110.6 3.0 73.3 10.0 40.6 12.2 29.5 70.3 23.4 16.5 0.3 39.5 45.9 52.1 3.5 4.3 25.1 22.0 24.6 17.3 6.7 14.6 30.5 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA1 "ANX1, LPC1" ENSG00000135046 "Annexin A1" P04083 9 73151865-73170393 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Immunity, Inflammatory response, Innate immunity" "Phospholipase A2 inhibitor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 7527.7" "Cell type enhanced" "Detected in many" "Squamous epithelial cells: 3632.9;Syncytiotrophoblasts: 7071.8;Urothelial cells: 4808.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 2816.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011271, HPA011272, CAB013023, CAB035987, CAB058693" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA Yes 3000000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "CAB013023: AB_2533983, CAB035987: , CAB058693: AB_2665585, HPA011271: AB_1844883, HPA011272: AB_1844884" "unprognostic (2.53e-2)" "unprognostic (1.31e-1)" "unprognostic (9.08e-2)" "prognostic favorable (5.71e-5)" "unprognostic (1.53e-2)" "unprognostic (4.28e-2)" "unprognostic (1.82e-2)" "unprognostic (1.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.54e-3)" "unprognostic (1.47e-1)" "unprognostic (9.82e-3)" "unprognostic (1.13e-1)" "unprognostic (8.55e-2)" "prognostic favorable (4.57e-5)" "prognostic unfavorable (6.19e-6)" 719.8 60.3 27.5 268.3 35.1 2132.2 442.6 24.8 44.4 952.0 32.8 152.7 64.1 116.2 58.6 7527.7 264.6 329.4 145.3 28.4 53.4 67.9 54.7 470.4 67.9 55.5 46.4 109.4 61.8 28.2 98.1 559.4 36.5 165.3 103.2 6.5 1547.5 154.9 47.6 213.8 88.7 261.5 40.4 79.6 90.2 17.9 45.9 109.9 206.8 89.1 1485.5 386.3 1536.1 43.2 960.2 1485.7 65.8 68.4 905.8 855.6 4.2 1614.6 1008.5 656.3 441.9 43.5 841.0 2.2 520.1 1426.5 1441.9 1147.7 142.6 984.1 516.8 541.6 10.3 73.2 398.5 1.4 719.4 160.9 34.7 495.7 800.6 664.7 1294.6 604.0 947.8 85.4 309.3 39.5 822.6 4.3 287.0 87.7 82.6 379.7 597.6 0.9 369.1 3.2 1495.9 200.4 1.0 0.7 556.6 14.7 377.9 862.7 3.5 24.3 1176.2 761.8 478.9 1058.2 845.1 6.8 2.0 3.6 1757.9 147.8 1171.2 2816.9 1237.6 2227.6 744.1 328.7 757.0 13.7 662.7 664.5 1513.3 3.3 190.7 348.5 128.4 443.6 324.0 53.2 134.5 2021.5 27.5 35.1 24.8 44.4 28.4 53.4 55.5 46.4 36.5 40.4 45.9 43.2 447.4 583.3 415.2 1.6 39.0 846.7 2486.8 2417.6 1748.3 0.1 225.0 417.1 22.5 58.6 2214.7 62.5 0.0 1543.4 602.1 32.2 0.0 167.4 8.2 2037.4 241.6 362.2 5.3 81.2 3.7 23.1 1747.7 732.0 86.6 1993.5 2550.6 0.1 136.7 6.5 593.8 0.0 0.1 20.8 1330.6 545.0 1190.3 7.3 222.4 901.7 307.7 29.0 575.0 0.2 319.3 0.5 0.6 733.2 5.5 9.4 140.4 1552.2 0.1 5.7 1996.9 0.0 65.7 728.2 413.3 2.3 4.0 3632.9 597.7 7071.8 1348.3 3.0 12.6 4808.1 ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 144.3;intestine: 293.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 180.1;Enteroendocrine cells: 44.9;Intestinal goblet cells: 161.1;Paneth cells: 58.1;Proximal enterocytes: 125.2;Undifferentiated cells: 38.5" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A549: 27.8;HDLM-2: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" 0.2 0.0 1.1 1.6 2.6 0.0 0.4 2.6 2.2 0.4 1.1 21.6 293.6 1.5 2.2 0.2 58.4 144.3 0.1 1.1 1.5 7.0 20.2 0.2 0.2 4.1 2.9 0.4 0.4 0.0 0.0 0.0 3.3 0.5 36.1 4.3 0.1 24.3 0.0 0.1 219.5 2.9 3.3 0.0 0.8 4.2 2.1 0.1 0.0 0.0 0.0 0.5 0.1 5.3 0.0 27.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 14.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.0 0.0 0.0 0.0 1.7 1.6 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.6 2.6 2.2 1.1 1.5 4.1 2.9 3.3 3.3 2.1 5.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.2 0.1 1.1 0.4 180.1 0.0 0.0 0.0 0.0 0.0 6.2 3.9 1.4 1.1 4.5 3.6 0.2 44.9 2.7 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.2 0.0 1.0 161.1 0.0 0.0 0.0 1.4 1.2 0.3 0.0 0.0 0.0 0.3 0.0 0.5 1.2 0.1 58.1 0.0 0.0 0.0 125.2 27.6 2.9 10.9 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.4 0.1 38.5 0.1 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 337.7" "Cell type enhanced" "Detected in many" "Adipocytes: 322.7;Alveolar cells type 1: 589.7;Ductal cells: 434.5;Exocrine glandular cells: 305.3;Pancreatic endocrine cells: 754.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 320 "neutrophil: 207.7" "Lineage enriched" "Detected in single" 327 "granulocytes: 207.7" "Cell line enhanced" "Detected in many" "A-431: 419.5;CACO-2: 403.5;CAPAN-2: 563.7;EFO-21: 334.7;hTERT-HME1: 566.3;OE19: 502.1;RPTEC TERT1: 477.8" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 52.9 3.1 16.5 22.7 17.3 337.7 43.8 14.5 28.2 19.6 11.7 27.7 15.8 12.5 3.7 55.2 16.8 17.3 51.2 14.2 21.6 24.9 3.9 144.4 2.4 19.9 16.1 2.5 32.7 34.0 5.9 81.5 20.8 68.0 26.7 1.6 119.5 12.9 28.3 10.0 13.3 20.1 14.6 21.6 90.5 1.9 19.9 7.1 83.7 36.7 12.7 10.2 15.6 14.7 419.5 77.7 1.3 0.9 1.0 0.9 0.6 4.9 0.4 11.0 10.9 403.5 563.7 0.1 334.7 14.4 0.4 161.6 0.1 300.0 16.0 1.4 3.3 36.4 142.0 23.9 45.9 5.9 0.2 2.4 262.6 4.1 566.3 60.1 118.9 9.0 0.7 0.3 1.9 15.9 1.7 0.2 13.0 502.1 55.4 0.0 0.8 0.0 477.8 45.2 0.3 0.3 235.5 58.2 16.6 186.1 9.9 4.3 153.2 0.6 52.6 0.2 93.0 3.1 5.1 2.2 0.0 0.4 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 207.7 0.1 0.6 0.1 0.0 2.9 16.5 17.3 14.5 28.2 14.2 21.6 19.9 16.1 20.8 14.6 19.9 14.7 322.7 589.7 47.3 0.0 1.1 24.9 81.8 144.9 1.8 0.2 27.6 85.9 8.6 55.8 175.2 38.6 0.0 212.6 1.0 35.4 17.6 434.5 1.1 33.7 4.4 84.6 5.4 3.2 0.9 305.3 106.2 16.9 99.9 58.1 5.1 0.1 23.2 0.6 18.9 0.0 0.3 33.4 122.1 0.3 0.3 0.3 3.1 6.9 5.4 42.2 21.0 1.2 0.0 1.0 0.6 754.2 61.6 0.4 0.6 158.6 11.5 5.5 89.6 0.4 0.0 7.6 18.7 1.1 0.6 21.9 6.7 62.8 2.3 1.3 29.7 46.7 AOPEP "AP-O, APO, C90RF3, C9orf3, FLJ14675" ENSG00000148120 "Aminopeptidase O (putative)" Q8N6M6 9 94726604-95087159 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 148.2;Cytotrophoblasts: 65.9;Extravillous trophoblasts: 43.7;Syncytiotrophoblasts: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HeLa: 30.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004633, HPA072729" Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Cell Junctions" "HPA004633: AB_1078362, HPA072729: AB_2686553" "unprognostic (4.25e-2)" "unprognostic (1.07e-3)" "unprognostic (6.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.12e-1)" "unprognostic (2.75e-2)" "unprognostic (9.59e-2)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (1.34e-1)" "unprognostic (2.60e-2)" "unprognostic (2.80e-1)" "prognostic favorable (6.33e-5)" "unprognostic (2.31e-1)" "unprognostic (2.56e-1)" "unprognostic (3.29e-2)" "unprognostic (3.37e-2)" 5.6 6.6 11.8 4.9 20.4 2.2 7.0 16.9 16.3 8.1 23.8 6.9 4.3 18.5 8.3 16.9 10.3 12.1 29.4 15.9 15.5 7.2 7.6 10.4 2.2 23.0 15.7 8.1 11.2 16.3 5.7 24.3 20.7 14.3 5.8 4.7 12.2 15.2 30.5 38.6 5.0 15.8 11.1 5.0 5.7 6.0 15.4 2.6 11.2 15.3 5.6 7.7 6.8 40.5 6.8 27.6 3.3 5.3 3.4 3.8 12.4 6.4 3.0 6.3 4.1 6.3 8.7 2.1 5.3 9.8 8.7 24.8 5.7 6.1 3.4 13.2 4.9 2.0 30.1 5.8 6.1 1.8 1.4 4.4 23.7 5.5 4.1 17.7 3.5 3.3 3.4 3.0 11.4 10.1 2.8 2.3 4.4 7.8 10.7 4.2 9.4 2.7 11.0 6.4 6.6 9.7 11.2 9.4 2.5 8.5 10.8 1.5 2.7 2.9 2.8 10.8 3.4 2.5 3.6 1.0 9.8 1.7 4.8 0.0 1.4 0.9 1.4 1.0 0.8 0.9 1.1 1.2 2.2 2.2 0.8 1.0 0.5 1.4 0.7 2.1 0.8 0.7 11.8 20.4 16.9 16.3 15.9 15.5 23.0 15.7 20.7 11.1 15.4 40.5 20.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 148.2 0.0 0.0 0.0 0.0 65.9 1.7 0.0 0.0 0.0 0.0 0.0 0.0 7.4 0.0 0.0 0.0 0.0 43.7 13.8 0.0 0.0 0.0 0.0 0.0 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 88.2 0.2 0.0 0.0 0.0 AP2M1 "AP50, CLAPM1, mu2" ENSG00000161203 "Adaptor related protein complex 2 subunit mu 1" Q96CW1 3 184174689-184184091 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036849, HPA069870" Uncertain Supported "Plasma membrane" NA NA 7500 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA036849: AB_10672101, HPA069870: AB_2686217" "unprognostic (1.16e-1)" "unprognostic (1.35e-2)" "unprognostic (5.28e-3)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (9.12e-4)" "unprognostic (3.80e-3)" "unprognostic (2.09e-1)" "unprognostic (5.53e-2)" "unprognostic (4.11e-2)" "unprognostic (9.18e-2)" "prognostic unfavorable (7.45e-6)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (1.60e-2)" "unprognostic (1.28e-1)" 191.8 364.2 233.5 164.7 250.3 231.3 164.6 211.3 257.3 222.8 196.3 232.4 167.5 216.4 104.2 218.1 178.6 166.5 366.2 261.1 249.0 196.0 140.9 180.0 148.2 234.8 211.1 198.6 106.4 224.8 224.9 243.3 248.9 183.2 141.1 230.4 167.2 231.8 181.2 157.2 156.2 243.7 200.9 162.5 156.3 106.4 235.4 158.4 148.0 194.0 157.6 223.7 192.4 225.6 436.3 327.5 275.7 311.8 432.1 450.8 284.3 714.3 412.5 788.5 550.5 355.1 309.9 198.2 851.3 1076.1 516.1 480.0 376.3 482.9 647.1 409.8 470.4 512.2 365.8 317.9 508.9 254.8 311.5 577.0 269.4 501.1 318.5 711.0 595.3 258.3 250.0 377.1 750.1 993.6 330.1 151.2 674.1 388.1 484.7 302.7 351.5 393.7 489.7 389.3 292.0 212.6 561.3 696.4 335.1 427.5 934.4 305.7 645.0 497.1 400.1 492.4 960.2 336.9 318.7 441.6 937.1 369.9 331.7 194.4 294.8 244.9 137.5 238.8 136.2 114.3 127.6 134.0 268.7 112.7 107.7 111.8 127.7 170.2 206.8 134.1 185.4 441.0 233.5 250.3 211.3 257.3 261.1 249.0 234.8 211.1 248.9 200.9 235.4 225.6 146.8 54.5 50.7 41.4 84.8 124.9 177.2 275.1 97.9 174.2 108.0 98.2 195.9 112.9 133.5 114.0 70.9 400.9 117.3 155.9 375.6 243.7 326.6 69.3 131.2 172.2 140.8 277.8 62.0 161.3 327.1 161.5 71.4 78.5 149.1 173.6 182.4 78.0 576.9 277.6 63.4 119.0 201.4 137.1 162.9 347.8 164.7 185.1 199.3 34.7 369.4 199.4 130.7 26.2 46.1 232.1 153.1 214.8 100.2 138.8 253.8 290.7 58.3 125.9 197.2 106.9 278.0 83.3 101.7 128.5 126.6 513.6 102.6 278.1 154.1 185.1 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APC "DP2, DP2.5, DP3, PPP1R46" ENSG00000134982 "APC regulator of WNT signaling pathway" P25054 5 112707498-112846239 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.8" "Cell type enhanced" "Detected in many" "Astrocytes: 536.4;Bipolar cells: 196.9;Excitatory neurons: 165.8;Inhibitory neurons: 236.4;Oligodendrocyte precursor cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013349, HPA013362" Supported Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA013349: AB_1844913, HPA013362: " "unprognostic (4.80e-2)" "unprognostic (1.19e-1)" "unprognostic (3.72e-2)" "unprognostic (1.14e-1)" "unprognostic (1.10e-1)" "unprognostic (7.09e-3)" "unprognostic (1.62e-1)" "unprognostic (8.10e-3)" "unprognostic (2.35e-1)" "unprognostic (4.85e-3)" "unprognostic (1.27e-1)" "unprognostic (4.18e-2)" "unprognostic (1.02e-2)" "unprognostic (1.07e-1)" "unprognostic (3.35e-1)" "unprognostic (2.23e-2)" "unprognostic (1.96e-1)" 6.9 4.6 28.4 6.2 26.0 9.1 5.7 23.1 31.0 5.7 0.1 6.7 6.2 5.6 3.3 7.7 4.3 4.9 7.2 52.8 27.4 6.2 5.7 6.2 5.6 32.1 30.7 6.6 4.1 8.5 3.9 5.1 39.0 5.2 6.2 20.0 3.8 4.1 8.5 5.7 8.5 7.5 16.0 6.1 5.0 5.1 37.9 8.5 5.9 11.8 5.9 5.4 3.6 20.9 11.3 10.1 16.8 12.2 13.4 11.3 6.7 17.9 8.5 9.7 11.5 8.2 8.9 22.0 17.0 23.1 15.5 9.0 17.4 14.6 15.9 13.2 12.2 16.8 14.9 6.2 6.6 8.4 8.6 9.3 9.8 16.6 10.8 6.8 13.6 10.2 20.9 7.2 14.3 7.8 9.6 4.2 6.0 6.1 3.6 8.1 20.8 10.7 8.9 14.1 17.0 10.1 16.9 6.5 7.1 6.8 9.1 6.7 22.8 19.6 9.5 19.5 13.6 5.6 9.5 8.2 10.8 15.3 11.2 11.8 2.5 4.9 2.9 1.3 2.4 2.8 1.5 1.9 2.1 3.1 2.4 2.4 11.4 2.9 2.4 2.7 1.5 1.0 28.4 26.0 23.1 31.0 52.8 27.4 32.1 30.7 39.0 16.0 37.9 20.9 40.6 51.3 23.6 536.4 21.9 11.2 8.9 10.1 19.9 196.9 13.1 14.9 56.6 18.6 20.1 0.0 66.7 5.4 28.9 28.6 0.0 18.7 10.5 20.1 27.6 31.2 27.5 17.4 165.8 19.5 6.5 25.9 19.4 29.7 19.0 28.7 26.7 13.9 16.3 79.1 236.4 17.2 2.0 18.9 12.4 5.5 17.7 27.8 17.8 85.3 30.7 23.4 23.7 196.6 150.8 20.3 34.7 19.5 22.9 10.4 37.2 5.1 18.0 41.5 39.5 44.1 34.0 19.2 30.4 26.5 11.6 2.9 22.4 27.1 16.0 8.9 APLP1 APLP ENSG00000105290 "Amyloid beta precursor like protein 1" P51693 19 35867899-35879792 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Endocytosis" Heparin-binding Neurodegeneration "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 1201.6" "Group enriched" "Detected in many" 4 "Bipolar cells: 147.1;Horizontal cells: 161.5;Oligodendrocytes: 461.3" "Cancer enhanced" "Detected in many" "glioma: 63.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 81.6;AN3-CA: 162.9;HMC-1: 76.0;SCLC-21H: 87.2;SH-SY5Y: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028970, HPA028971" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 6400000 "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA028970: AB_2672847, HPA028971: AB_10601334" "unprognostic (1.33e-2)" "unprognostic (2.07e-1)" "unprognostic (9.36e-3)" "prognostic unfavorable (3.87e-4)" "unprognostic (7.32e-3)" "unprognostic (1.26e-2)" "unprognostic (1.04e-3)" "unprognostic (2.24e-2)" "unprognostic (4.98e-2)" "unprognostic (6.16e-2)" "unprognostic (2.35e-2)" "unprognostic (1.13e-1)" "unprognostic (2.57e-11)" "unprognostic (1.38e-3)" "unprognostic (7.12e-2)" "unprognostic (5.43e-2)" "prognostic unfavorable (2.65e-5)" 3.0 31.5 417.1 3.1 718.0 0.4 1.4 680.9 552.4 3.1 218.6 4.4 1.8 3.1 1.3 1.5 2.7 5.5 10.8 438.3 465.8 4.9 0.6 1.9 1.4 783.2 627.4 1.4 75.0 22.3 151.4 0.9 710.7 2.1 2.2 56.3 1.8 1.9 0.5 1.1 2.1 3.2 605.9 0.5 28.1 13.1 598.3 0.8 1.5 0.5 1.5 1.2 2.1 1201.6 4.4 40.0 81.6 162.9 7.1 3.2 10.4 5.6 3.5 7.8 1.1 7.3 6.3 0.8 66.5 21.0 27.7 2.2 26.1 2.6 5.2 48.9 3.7 0.3 10.6 5.2 2.0 0.2 76.0 3.6 1.8 3.2 0.1 28.8 3.1 6.1 2.7 1.2 25.0 8.3 0.2 0.3 3.9 16.5 16.5 7.2 0.4 1.1 1.4 1.1 87.2 89.3 23.1 3.8 0.8 23.9 20.8 4.3 1.3 61.3 28.8 32.9 4.3 2.4 1.6 0.3 42.3 1.1 33.3 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.0 0.0 417.1 718.0 680.9 552.4 438.3 465.8 783.2 627.4 710.7 605.9 598.3 1201.6 2.5 6.4 0.0 12.4 0.6 1.3 2.6 0.7 1.2 147.1 0.4 1.1 6.2 1.5 0.2 0.0 12.5 0.3 0.3 0.4 0.0 2.0 27.6 1.3 1.2 2.8 34.9 0.0 55.5 4.2 6.4 2.8 10.2 3.2 0.0 0.1 0.7 0.4 0.4 161.5 46.8 1.1 2.0 0.3 1.6 15.8 1.2 1.1 5.4 12.2 0.0 14.6 0.0 19.1 461.3 3.1 0.1 0.0 0.4 1.9 0.0 0.1 0.2 38.6 0.0 1.9 1.8 14.5 28.7 0.1 0.6 0.4 0.5 0.1 0.2 1.3 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOC3 ENSG00000110245 "Apolipoprotein C3" P02656 11 116829706-116833072 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism, Lipid transport, Transport" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 25 "liver: 27649.0" "Cell type enriched" "Detected in some" 8 "Hepatocytes: 84691.9" "Cancer enriched" "Detected in many" 643 "liver cancer: 4021.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "CACO-2: 107.3;Hep G2: 296.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA065365, HPA073918" Supported Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Secreted to blood" NA NA 106000000000 45000000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Nucleoplasm "Nucleoli, Cell Junctions" "HPA065365: AB_2732733, HPA073918: " "prognostic favorable (3.77e-4)" "unprognostic (2.33e-1)" "prognostic unfavorable (6.87e-5)" "unprognostic (1.60e-2)" "unprognostic (5.21e-2)" 4.1 1.2 0.0 1.0 0.0 0.0 2.5 0.0 0.1 0.4 0.0 7.2 907.0 0.5 0.0 1.1 1.9 0.0 1.6 0.0 0.0 18.2 27649.0 1.4 0.9 0.0 0.0 0.8 2.4 0.0 0.8 0.9 0.0 0.6 0.0 0.0 0.6 0.0 0.6 1.2 1106.7 0.5 0.0 8.0 1.5 1.0 0.0 0.5 0.8 0.2 0.0 0.1 0.7 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.0 0.0 0.1 107.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 296.2 0.0 10.7 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.2 2.3 0.2 0.0 0.0 0.0 6.3 3.9 0.0 0.1 1.1 3.8 4.1 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.2 0.0 3.4 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 67.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 674.9 0.0 0.0 0.0 0.2 0.0 0.0 3.9 0.0 4.2 0.0 0.0 39.7 0.0 823.7 0.0 0.4 1.5 0.1 0.0 0.0 0.0 0.3 707.9 84691.9 1.1 0.0 0.0 264.5 0.0 1107.4 0.0 12.6 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.0 0.0 0.0 0.0 10473.3 121.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 39.8 0.0 135.5 0.0 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 APPL1 APPL ENSG00000157500 "Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 1" Q9UKG1 3 57227726-57278105 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle" "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 28.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011138 Approved Approved "Vesicles,Plasma membrane,Actin filaments,Cytosol" NA No 10000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Vesicles, Plasma membrane" "Actin filaments, Cytosol" "HPA011138: AB_1844959" "unprognostic (1.39e-1)" "unprognostic (3.45e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (3.68e-2)" "unprognostic (2.31e-3)" "unprognostic (1.30e-3)" "unprognostic (1.81e-2)" "unprognostic (1.05e-1)" "unprognostic (8.36e-2)" "unprognostic (9.05e-3)" "unprognostic (5.55e-2)" "prognostic favorable (7.26e-5)" "unprognostic (3.99e-2)" "unprognostic (8.76e-2)" "unprognostic (1.12e-2)" "unprognostic (1.55e-1)" 15.6 11.6 9.5 14.8 9.7 15.1 18.9 12.9 11.3 17.1 6.8 14.2 12.6 17.1 10.6 16.9 11.7 13.0 24.7 9.7 11.3 16.5 12.9 13.6 16.7 9.8 10.1 22.7 29.6 25.1 7.8 14.3 10.1 15.0 14.0 13.5 15.2 14.4 44.2 20.1 14.6 15.3 10.4 15.8 15.2 8.0 10.2 18.9 19.8 26.6 19.6 13.4 11.9 10.7 30.2 12.9 12.2 45.4 21.2 29.7 26.2 15.5 9.5 15.4 17.8 14.9 17.5 47.3 6.2 24.6 24.7 5.9 33.7 27.3 26.6 36.1 15.0 27.6 19.5 16.1 22.7 59.6 19.1 21.8 24.3 19.3 21.3 31.3 25.3 30.2 9.0 30.0 17.8 10.4 48.7 15.4 19.5 21.6 21.7 1.7 49.1 26.1 27.7 16.7 12.5 26.5 21.1 32.3 21.0 16.7 15.7 39.6 23.4 25.1 17.5 37.4 29.9 27.0 41.8 33.2 27.4 29.1 17.1 2.0 5.3 3.8 3.7 4.5 4.9 17.9 3.8 3.3 10.9 28.3 3.3 2.5 1.4 7.4 3.6 18.0 1.9 2.7 9.5 9.7 12.9 11.3 9.7 11.3 9.8 10.1 10.1 10.4 10.2 10.7 82.9 51.3 45.5 19.6 106.6 52.9 47.3 46.9 83.6 40.5 67.2 92.8 100.1 47.1 47.4 42.3 31.3 46.9 70.9 29.0 58.7 58.6 42.5 35.4 92.8 66.2 45.6 20.0 49.7 60.3 44.7 68.6 40.2 59.4 23.4 60.8 40.0 44.1 52.2 52.2 50.4 36.2 42.7 68.6 50.6 22.1 73.0 71.0 19.6 33.7 87.8 56.6 56.7 43.2 62.2 51.7 25.5 76.0 62.8 38.7 41.0 58.8 18.1 55.4 52.6 94.3 61.2 64.9 44.2 105.7 69.6 28.0 45.4 73.7 49.1 25.8 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 68.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Erythroid cells: 1.3;granulocytes: 5.7;Hepatic stellate cells: 1.4;Macrophages: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.0;HMC-1: 7.1;K-562: 21.0;SH-SY5Y: 4.8" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 68.5 0.0 0.1 0.1 4.6 0.1 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.7 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 5.7 0.2 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.1 0.0 0.4 0.1 0.0 0.1 AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1923.3;Basal prostatic cells: 982.0;Collecting duct cells: 1609.3;Prostatic glandular cells: 1430.8;Squamous epithelial cells: 2189.3;Suprabasal keratinocytes: 2485.4;Urothelial cells: 2455.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cell line enhanced" "Detected in many" "HaCaT: 127.1;HeLa: 213.2;JURKAT: 130.7;RT4: 216.6;SK-BR-3: 149.7;U-266/70: 151.2;U-266/84: 213.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" 10.9 2.1 1.5 16.8 0.4 19.7 36.6 2.4 3.4 173.3 1.4 10.3 73.4 10.9 2.9 1526.1 25.4 9.4 31.5 5.3 0.4 131.7 118.6 114.0 16.1 16.0 1.6 12.1 43.1 2.0 2.8 6.0 21.0 85.6 10.1 1.7 399.7 36.8 5.3 581.9 100.5 3.2 0.2 110.1 35.9 2.8 0.8 233.9 2.3 26.7 172.5 688.6 529.9 0.9 0.6 38.6 1.9 0.0 67.7 12.2 1.0 0.3 0.9 0.9 1.1 20.5 12.0 0.5 9.1 0.0 0.5 127.1 6.2 0.7 0.2 61.6 6.0 4.3 213.2 1.9 0.4 1.3 1.3 1.9 6.5 0.5 0.2 0.2 0.5 130.7 67.4 58.8 6.9 29.1 60.4 23.0 5.3 88.6 0.7 0.9 94.3 10.8 1.3 216.6 1.7 4.7 32.3 149.7 0.1 8.0 0.9 10.6 1.2 0.0 1.0 0.4 0.4 151.2 213.6 14.5 0.5 0.4 0.2 1.6 0.5 0.1 20.2 0.4 181.7 11.3 171.9 52.8 0.3 3.0 97.3 47.1 2.3 3.0 0.5 11.1 205.4 43.0 1.5 0.4 2.4 3.4 5.3 0.4 16.0 1.6 21.0 0.2 0.8 0.9 9.2 38.5 249.9 0.0 42.4 1923.3 982.0 381.4 811.0 9.7 56.8 27.8 3.4 157.3 436.3 1609.3 2.1 0.9 21.6 2.7 0.0 37.4 2.2 82.3 21.4 37.1 8.3 71.4 0.3 48.9 2.0 27.5 16.3 96.2 20.8 0.2 16.4 137.3 2.2 0.0 0.1 104.0 315.3 3.5 122.9 0.6 33.2 15.3 158.3 0.0 1.6 0.4 4.1 0.5 0.2 28.5 8.1 1.2 246.9 1430.8 343.1 31.9 546.0 0.5 0.0 10.2 35.8 0.7 1.9 2189.3 2485.4 50.2 73.4 1.6 7.3 2455.4 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 ARAP1 CENTD2 ENSG00000186635 "ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1" Q96P48 11 72685069-72793599 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020703, HPA070383" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 36000 "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "CAB020703: , HPA070383: AB_2686262" "unprognostic (3.60e-2)" "unprognostic (7.68e-2)" "unprognostic (6.19e-2)" "unprognostic (5.98e-2)" "unprognostic (5.76e-2)" "unprognostic (1.64e-2)" "prognostic unfavorable (6.45e-4)" "unprognostic (4.01e-2)" "unprognostic (4.07e-1)" "unprognostic (5.95e-2)" "prognostic favorable (2.04e-5)" "unprognostic (1.84e-1)" "unprognostic (1.05e-3)" "unprognostic (6.93e-2)" "unprognostic (2.57e-2)" "prognostic favorable (6.41e-4)" "unprognostic (7.56e-3)" 41.5 63.5 40.0 58.6 48.6 97.5 33.4 37.9 50.4 44.1 62.9 35.5 29.6 38.9 14.0 37.7 48.3 44.2 42.9 42.2 38.5 47.8 40.2 71.8 53.4 50.6 42.3 49.4 37.1 20.4 48.9 35.5 45.9 44.9 18.2 8.6 33.3 25.7 20.1 47.1 43.3 28.7 40.1 117.5 31.3 16.4 50.8 32.2 46.6 20.1 25.2 39.7 37.5 56.8 19.7 41.9 15.2 18.5 63.4 42.9 23.1 26.2 46.5 29.8 29.3 56.0 50.8 42.9 51.3 44.4 40.7 64.5 23.2 64.4 12.5 50.9 28.4 36.6 40.3 81.9 43.7 25.1 98.7 47.5 65.4 48.7 23.4 36.2 33.2 31.3 31.5 17.4 13.9 40.3 38.9 89.3 9.5 35.1 25.9 36.8 23.2 21.3 27.5 61.1 15.7 32.0 19.1 27.9 84.8 19.5 25.1 56.8 37.5 41.0 28.5 42.8 16.4 27.4 14.3 23.0 21.8 37.4 22.3 19.3 24.8 30.7 8.9 39.4 5.2 6.6 5.9 6.8 15.9 4.7 4.5 5.4 50.8 13.4 51.3 5.3 6.7 17.6 40.0 48.6 37.9 50.4 42.2 38.5 50.6 42.3 45.9 40.1 50.8 56.8 8.9 28.9 32.3 33.6 16.1 7.4 7.5 14.3 15.4 4.3 8.7 7.9 2.6 7.2 9.0 16.5 33.3 9.2 18.3 16.5 9.8 13.5 50.1 14.1 11.7 7.8 23.3 9.9 7.7 7.5 8.9 22.4 16.3 9.1 10.8 36.9 9.7 10.8 43.0 0.0 7.0 12.8 12.2 45.6 25.1 6.4 20.8 57.3 8.8 30.0 29.0 7.4 21.6 17.6 31.5 12.1 10.9 15.1 12.3 4.8 20.9 5.3 20.2 2.8 0.0 8.6 8.8 0.4 2.8 10.8 5.4 4.9 12.4 10.5 15.1 7.4 ARF1 ENSG00000143761 "ADP ribosylation factor 1" P84077 1 228082660-228099212 "Disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007742 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB007742: AB_562043" "unprognostic (9.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.30e-2)" "unprognostic (2.50e-3)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (8.95e-3)" "unprognostic (6.74e-2)" "unprognostic (2.96e-2)" "unprognostic (5.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.56e-1)" "unprognostic (8.57e-2)" "unprognostic (1.94e-1)" 268.3 282.5 213.8 176.7 222.5 426.9 241.9 188.1 261.9 249.1 215.1 259.8 242.6 266.6 193.1 304.7 247.5 189.2 340.0 242.7 231.3 257.0 324.7 298.2 185.0 200.6 201.6 237.3 327.6 296.9 299.1 276.9 207.6 244.0 177.3 96.7 355.2 203.9 330.9 237.3 240.8 176.2 196.6 251.4 265.6 193.9 218.9 184.4 240.3 206.4 154.7 229.0 233.1 206.4 476.6 321.6 257.4 257.9 289.9 362.6 425.7 409.5 433.0 444.3 386.8 383.6 442.7 239.9 428.8 438.3 204.6 298.8 316.4 399.4 219.4 355.3 506.8 234.3 209.8 386.6 559.5 342.1 333.8 350.4 476.7 408.6 427.0 374.1 443.3 267.0 456.0 533.3 431.4 341.8 350.0 495.9 331.7 656.7 643.0 279.0 228.1 750.6 315.1 242.1 362.6 320.0 265.9 790.0 466.8 87.8 543.9 681.0 406.0 324.6 256.5 479.4 626.8 498.5 301.0 331.1 445.9 285.0 670.6 1003.7 556.5 625.5 387.3 527.8 472.4 276.7 328.0 359.8 423.6 261.3 253.2 280.8 863.6 345.5 528.2 571.4 417.9 1082.4 213.8 222.5 188.1 261.9 242.7 231.3 200.6 201.6 207.6 196.6 218.9 206.4 276.9 173.1 185.2 25.8 205.1 262.6 281.7 248.0 104.2 114.3 209.1 172.0 139.8 125.8 208.1 115.8 45.9 373.7 267.8 487.8 230.9 422.7 236.3 164.6 218.7 247.2 230.1 173.8 42.3 404.5 565.8 227.3 142.8 240.8 198.3 128.8 152.4 124.8 409.4 158.2 41.1 436.9 213.6 198.8 256.2 429.9 229.2 300.1 300.6 35.6 356.0 162.2 214.2 30.7 40.7 400.2 407.2 227.2 282.8 344.6 370.1 173.3 180.7 80.2 230.1 149.6 416.0 321.1 155.7 158.3 286.0 676.7 224.9 174.6 335.2 370.0 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP18 "bA307O14.2, MacGAP" ENSG00000146376 "Rho GTPase activating protein 18" Q8N392 6 129576132-129710177 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 253.6;Respiratory ciliated cells: 265.3;Syncytiotrophoblasts: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 395.8;LHCN-M2: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA031595 Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 1: Thyroid gland - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Nuclear speckles, Plasma membrane" "HPA031595: AB_10959905" "unprognostic (6.39e-2)" "unprognostic (1.60e-1)" "unprognostic (5.45e-2)" "unprognostic (5.49e-2)" "unprognostic (3.05e-1)" "unprognostic (3.17e-1)" "unprognostic (9.32e-3)" "unprognostic (1.25e-2)" "unprognostic (2.98e-2)" "unprognostic (3.12e-2)" "prognostic unfavorable (2.54e-4)" "unprognostic (4.08e-1)" "unprognostic (2.29e-3)" "unprognostic (2.22e-1)" "unprognostic (3.05e-2)" "unprognostic (5.52e-2)" "unprognostic (1.08e-1)" 20.5 37.2 3.4 13.0 2.5 4.3 13.4 2.4 2.8 14.9 15.1 14.8 24.8 6.7 20.2 6.0 28.3 15.4 6.0 2.9 4.1 28.4 6.3 28.7 9.4 4.7 5.7 6.0 33.2 14.2 6.7 20.8 4.3 9.9 15.0 2.6 14.6 8.4 10.6 4.0 27.3 10.6 3.5 9.0 27.9 8.3 6.4 6.1 23.0 13.0 7.9 12.6 4.1 3.7 8.6 18.8 1.9 2.6 17.8 25.0 15.1 64.0 48.8 27.7 18.5 10.0 14.1 7.1 30.6 43.2 8.8 11.0 13.4 20.9 51.3 7.0 5.7 46.7 13.8 57.3 25.4 6.9 395.8 15.9 3.2 50.4 44.7 57.8 79.8 0.0 25.3 17.4 113.1 2.3 0.1 6.8 2.0 16.0 4.5 0.3 8.5 13.7 84.6 4.8 0.0 0.1 5.3 8.8 32.3 9.3 9.7 8.1 61.6 28.8 4.1 2.3 51.8 7.8 6.0 4.8 9.7 12.7 40.9 12.0 5.1 13.5 4.9 5.8 3.1 2.9 2.5 5.5 4.8 1.7 0.4 2.6 3.9 2.5 3.2 11.8 2.8 6.0 3.4 2.5 2.4 2.8 2.9 4.1 4.7 5.7 4.3 3.5 6.4 3.7 139.5 57.7 33.3 1.6 13.0 13.0 17.7 15.7 10.8 0.7 53.4 14.7 4.1 17.2 39.5 38.6 2.1 92.7 31.0 19.0 150.6 48.2 20.7 176.1 5.8 89.2 13.1 10.9 16.8 120.5 24.9 45.3 63.2 35.7 253.6 34.7 11.0 5.0 110.4 0.0 23.1 22.1 63.1 48.4 112.4 21.2 3.7 163.9 7.2 43.1 23.9 16.4 28.8 12.5 2.2 102.4 25.0 1.2 26.4 18.5 69.8 31.7 265.3 0.9 26.3 38.9 32.5 10.6 1.1 11.2 12.9 212.3 35.9 69.1 31.3 19.1 ARHGAP19 "FLJ00194, MGC14258" ENSG00000213390 "Rho GTPase activating protein 19" Q14CB8 10 97222173-97292673 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Spermatocytes: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA035777, HPA043231" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane" "HPA035777: AB_2674777, HPA043231: AB_10796791" "unprognostic (5.88e-2)" "unprognostic (2.39e-2)" "unprognostic (2.47e-2)" "unprognostic (1.91e-2)" "unprognostic (1.68e-1)" "unprognostic (8.79e-3)" "unprognostic (1.60e-3)" "unprognostic (2.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (6.76e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.23e-2)" "unprognostic (4.29e-2)" 3.2 2.1 2.4 7.1 3.9 18.8 7.6 2.9 2.0 3.7 0.6 4.3 3.6 5.5 2.6 4.0 4.7 3.4 3.3 1.6 3.2 3.9 2.4 4.7 13.3 4.3 3.2 9.3 1.6 5.5 0.5 5.3 4.4 3.6 4.5 3.2 3.2 3.0 1.8 3.6 5.3 4.5 3.3 7.9 3.6 18.5 2.9 21.3 3.2 4.2 13.2 2.9 2.0 5.9 18.5 6.0 31.9 56.0 2.1 8.3 9.8 9.0 9.1 13.9 9.9 11.2 16.1 40.9 7.4 6.2 8.3 12.3 27.1 11.2 17.8 20.4 14.7 27.0 7.8 7.8 2.1 42.1 27.8 4.2 3.9 9.8 22.3 4.7 19.6 57.3 27.1 21.0 12.1 8.9 39.3 9.1 16.9 12.2 5.5 45.5 27.1 11.4 4.2 7.8 2.5 14.5 6.7 3.1 14.5 11.9 19.4 22.2 9.1 5.7 6.8 8.9 23.6 18.6 20.7 54.3 7.0 48.7 6.4 21.5 7.2 11.1 5.0 6.8 4.7 5.5 4.9 4.7 5.4 5.3 5.6 5.0 15.8 4.4 6.1 3.0 6.3 5.5 2.4 3.9 2.9 2.0 1.6 3.2 4.3 3.2 4.4 3.3 2.9 5.9 5.8 3.2 3.2 0.0 4.1 0.9 1.4 2.8 3.4 2.8 3.6 8.8 1.9 2.8 1.6 0.0 0.0 2.0 3.6 2.2 0.0 1.3 9.1 2.4 2.6 5.4 0.0 6.7 0.0 1.6 3.5 3.9 1.5 3.6 5.1 5.6 11.7 2.6 3.5 6.7 0.0 1.9 2.0 9.3 1.9 6.3 3.4 6.1 1.8 0.0 5.4 1.7 5.2 0.0 0.0 1.4 2.9 4.1 5.8 2.6 2.6 0.7 4.8 1.3 0.0 3.1 2.2 13.7 10.4 5.3 2.4 1.0 3.5 3.4 3.5 1.6 ARHGAP21 "ARHGAP10, KIAA1424" ENSG00000107863 "Rho GTPase activating protein 21" Q5T5U3 10 24583609-24723887 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 111.2" "Cell type enhanced" "Detected in all" "Excitatory neurons: 266.5;Oligodendrocyte precursor cells: 336.7;Oligodendrocytes: 827.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036610, HPA057861" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions, Actin filaments" "Plasma membrane" "HPA036610: AB_10669910, HPA057861: AB_2683546" "unprognostic (7.65e-2)" "unprognostic (1.61e-2)" "unprognostic (1.88e-1)" "unprognostic (5.84e-2)" "unprognostic (2.69e-1)" "unprognostic (3.59e-1)" "unprognostic (1.12e-3)" "unprognostic (5.35e-2)" "unprognostic (9.75e-2)" "unprognostic (3.34e-2)" "unprognostic (2.65e-3)" "unprognostic (3.23e-1)" "unprognostic (3.14e-2)" "unprognostic (1.53e-1)" "unprognostic (3.32e-1)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" 28.4 18.0 44.3 10.3 77.7 7.2 16.1 56.7 58.1 19.7 0.0 16.6 12.9 19.9 8.6 10.8 17.5 17.9 21.2 49.1 48.3 11.0 13.1 21.7 5.3 76.3 63.1 31.9 14.9 14.6 12.1 16.6 66.7 10.8 18.5 41.3 24.5 11.5 17.7 6.8 16.3 17.8 48.4 8.9 27.1 14.6 58.0 11.4 12.8 23.0 6.0 13.8 9.0 111.2 59.0 25.1 60.9 52.3 42.2 59.1 21.6 41.6 26.6 24.5 34.0 18.4 36.8 10.9 14.0 64.3 37.7 38.1 31.6 40.4 35.9 38.0 20.5 64.9 54.7 13.8 25.5 0.0 9.9 24.4 45.0 32.1 34.4 36.9 42.3 16.1 27.9 96.3 50.0 11.6 30.2 2.3 9.7 20.8 13.6 7.0 21.4 6.2 17.2 10.2 10.5 10.9 27.9 16.0 32.6 18.1 16.3 9.1 47.8 35.3 22.7 40.0 30.6 11.0 20.3 7.8 36.2 11.4 24.7 0.9 0.2 0.4 0.1 0.4 0.1 0.0 0.2 0.3 0.3 0.0 0.6 0.3 0.0 0.2 0.2 0.4 0.4 0.2 44.3 77.7 56.7 58.1 49.1 48.3 76.3 63.1 66.7 48.4 58.0 111.2 47.9 86.6 33.1 246.8 6.5 29.6 13.2 23.6 14.8 144.0 17.5 26.0 37.4 24.3 45.0 5.5 68.8 23.8 6.9 44.6 1.9 21.4 5.0 36.2 148.7 34.9 16.2 15.2 266.5 27.6 21.0 73.0 82.0 54.2 17.1 135.8 26.0 20.9 14.6 132.9 153.8 28.3 14.2 32.8 31.8 8.3 92.9 38.9 19.6 171.4 11.0 194.0 2.1 336.7 827.4 37.1 34.6 59.5 15.2 27.4 21.9 6.5 30.3 53.5 26.3 60.4 43.2 27.4 35.6 18.1 20.2 12.6 11.8 62.2 29.0 29.5 ARHGAP22 RhoGAP2 ENSG00000128805 "Rho GTPase activating protein 22" Q7Z5H3 10 48446036-48656265 "Predicted intracellular proteins" "Angiogenesis, Differentiation, Transcription, Transcription regulation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 22.6" "Cell type enhanced" "Detected in many" "Late spermatids: 122.7;Microglial cells: 227.7;Oligodendrocyte precursor cells: 141.8;Oligodendrocytes: 200.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 68.8;LHCN-M2: 64.8;TIME: 66.2;U-87 MG: 82.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020696, HPA040391, HPA064439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB020696: , HPA040391: AB_2676957, HPA064439: AB_2685266" "unprognostic (1.87e-1)" "unprognostic (3.98e-2)" "unprognostic (2.38e-2)" "unprognostic (2.62e-1)" "unprognostic (1.07e-1)" "unprognostic (6.74e-3)" "unprognostic (4.81e-3)" "unprognostic (2.78e-1)" "unprognostic (1.66e-1)" "unprognostic (3.03e-1)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "prognostic unfavorable (2.16e-8)" "unprognostic (7.40e-2)" "unprognostic (1.60e-1)" "unprognostic (9.39e-2)" "unprognostic (3.66e-2)" 2.6 1.9 12.0 3.0 15.7 1.4 1.6 17.6 14.5 1.6 7.7 2.0 0.6 1.1 0.7 1.4 1.8 1.8 4.4 11.9 12.7 1.3 0.8 2.0 2.7 22.6 17.0 4.8 1.7 0.9 2.0 0.8 20.1 3.3 1.0 0.4 2.0 1.1 1.9 2.2 1.6 1.4 16.9 2.8 1.2 4.8 17.0 2.8 6.6 1.6 2.2 2.1 2.2 22.2 6.2 1.4 0.4 0.0 5.1 20.8 4.3 31.9 15.1 3.0 4.1 7.0 0.9 0.0 1.2 13.1 2.1 12.4 0.4 11.2 5.4 0.6 11.5 18.2 0.2 0.1 2.7 2.0 2.0 5.0 11.2 37.1 3.0 68.8 20.6 0.0 17.4 3.0 64.8 0.2 0.2 0.1 7.2 0.0 0.5 0.1 0.0 7.9 6.5 0.7 1.1 6.4 1.5 0.1 0.6 0.6 0.4 0.3 66.2 30.1 0.4 3.8 23.8 0.0 0.0 0.0 82.5 0.3 4.9 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 12.0 15.7 17.6 14.5 11.9 12.7 22.6 17.0 20.1 16.9 17.0 22.2 0.9 0.0 1.7 4.2 2.9 3.4 4.1 6.8 4.6 1.1 0.8 3.0 2.9 1.5 2.9 0.0 2.1 11.6 3.2 0.2 0.0 2.8 53.6 0.7 1.6 2.4 0.0 10.9 51.7 4.4 0.7 6.5 0.5 1.0 0.0 4.4 1.8 0.0 10.3 0.0 29.8 0.3 2.0 7.6 14.2 122.7 2.8 15.6 1.8 227.7 14.8 1.8 0.0 141.8 200.8 2.5 0.0 6.0 0.5 1.9 0.0 0.2 3.8 1.4 0.0 1.6 4.2 1.6 4.3 0.4 0.6 1.0 0.7 10.6 0.1 0.6 ARHGAP23 KIAA1501 ENSG00000275832 "Rho GTPase activating protein 23" Q9P227 17 38419280-38512385 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.4;Hepatic stellate cells: 46.1;Oligodendrocytes: 129.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 296.7;RT4: 115.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019818, HPA047291" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" Cytosol "HPA019818: AB_1844993, HPA047291: AB_2680012" "unprognostic (3.35e-1)" "unprognostic (5.11e-2)" "unprognostic (6.43e-2)" "prognostic unfavorable (6.87e-5)" "unprognostic (9.53e-2)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (1.99e-1)" "unprognostic (5.56e-2)" "unprognostic (1.50e-3)" "prognostic unfavorable (3.24e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (5.38e-5)" "unprognostic (8.36e-2)" "unprognostic (5.83e-2)" "unprognostic (4.57e-2)" "unprognostic (2.25e-1)" 25.6 13.8 36.2 8.3 66.2 10.7 18.8 47.2 54.6 25.9 5.5 22.8 3.0 28.4 3.7 60.8 18.4 7.8 27.3 34.4 37.5 11.8 2.9 28.0 4.1 63.7 59.6 18.1 3.5 3.1 6.2 19.4 54.1 19.9 2.8 8.5 12.8 12.5 10.6 61.1 10.4 11.6 43.0 30.7 13.4 16.1 66.1 5.4 9.5 5.8 11.0 36.3 29.5 97.8 32.5 17.2 15.2 5.1 9.5 31.1 19.6 44.8 49.5 37.7 21.8 56.8 55.1 0.7 35.2 102.5 18.7 296.7 1.7 62.3 26.6 3.5 3.3 0.0 55.1 0.4 47.2 3.0 0.3 18.8 11.8 27.7 17.3 31.0 39.4 6.0 0.6 8.3 21.6 0.0 10.2 6.3 9.0 1.2 6.3 17.0 33.0 10.4 16.0 115.7 3.7 8.8 26.9 0.1 0.3 21.2 6.7 7.9 57.7 62.6 22.9 12.9 12.1 6.5 7.3 1.9 16.3 8.1 56.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.2 66.2 47.2 54.6 34.4 37.5 63.7 59.6 54.1 43.0 66.1 97.8 27.2 12.8 1.5 23.8 0.7 9.9 17.5 10.6 9.1 59.4 1.7 3.9 20.4 1.5 13.2 3.7 0.0 27.0 0.2 0.1 0.0 2.9 7.6 8.5 10.0 34.9 0.0 4.0 9.3 1.4 3.1 11.6 3.1 5.7 0.0 4.9 46.1 0.5 5.1 26.9 16.2 0.4 2.0 2.5 4.2 21.0 9.0 1.2 1.8 9.4 0.2 9.6 0.0 20.1 129.2 7.0 0.1 7.2 1.7 15.4 0.0 0.2 8.3 3.4 0.0 10.9 7.6 13.5 2.7 27.5 25.9 16.6 1.8 1.3 0.3 42.2 ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 99.8" "Group enriched" "Detected in many" 4 "Astrocytes: 1364.3;Microglial cells: 905.0" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.9;memory B-cell: 47.3;naive B-cell: 36.8;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.3;dendritic cells: 12.7;monocytes: 15.9" "Cell line enhanced" "Detected in many" "ASC diff: 109.0;ASC TERT1: 65.5;HHSteC: 63.6;HUVEC TERT2: 121.9;RPTEC TERT1: 67.2;TIME: 87.0;U-138 MG: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" 14.6 2.2 6.5 7.5 5.1 18.7 9.2 6.2 5.8 5.5 3.9 7.4 7.3 9.4 4.6 6.1 4.1 10.9 27.3 5.7 6.6 99.8 9.5 15.7 10.5 15.7 11.5 5.5 30.1 8.1 5.4 22.4 17.2 5.4 6.1 8.4 10.6 7.2 10.2 7.0 10.3 14.1 12.1 16.4 26.0 3.4 10.4 7.5 27.8 7.7 15.5 9.1 5.6 19.1 3.0 6.2 4.4 0.1 109.0 65.5 4.8 21.5 28.5 5.2 8.4 0.1 0.0 2.8 7.4 48.8 6.4 0.0 0.2 9.0 11.0 0.0 1.2 3.6 0.6 0.2 63.6 0.4 0.0 48.4 0.9 10.3 4.7 23.9 121.9 0.0 6.6 0.4 46.1 0.0 0.1 0.0 0.3 1.5 11.3 0.6 22.4 11.8 67.2 0.0 2.3 2.3 2.5 3.5 7.8 4.7 0.4 0.2 87.0 59.9 1.2 4.4 0.3 0.3 0.0 3.9 10.1 2.2 19.9 0.0 15.9 0.0 0.0 3.0 0.0 47.3 0.0 0.0 3.8 36.8 0.0 0.0 5.5 0.0 2.3 12.7 0.0 3.1 6.5 5.1 6.2 5.8 5.7 6.6 15.7 11.5 17.2 12.1 10.4 19.1 14.0 57.7 28.8 1364.3 142.1 8.2 3.9 35.6 10.2 6.6 1.2 4.7 26.4 47.1 18.3 46.0 6.2 54.8 9.9 1.0 226.9 9.4 30.5 1.2 12.9 9.5 2.4 0.0 12.2 11.8 26.2 24.7 25.0 1.4 1.3 6.7 4.2 9.5 10.5 111.0 51.3 3.3 6.1 33.7 21.3 8.8 16.8 26.3 19.6 905.0 34.0 27.7 0.0 27.2 21.8 7.4 2.9 12.4 2.0 2.3 0.2 205.9 24.8 6.6 6.6 50.0 21.3 8.1 5.9 4.0 6.3 232.9 4.1 18.4 5.0 1.9 ARHGAP28 "FLJ10312, KIAA1314" ENSG00000088756 "Rho GTPase activating protein 28" Q9P2N2 18 6729716-6915716 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "placenta: 25.9;testis: 77.5" "Group enriched" "Detected in many" 14 "Early spermatids: 536.8;Late spermatids: 488.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "neutrophil: 3.0" "Lineage enriched" "Detected in single" 11 "granulocytes: 3.0" "Cell line enhanced" "Detected in many" "AF22: 30.4;CACO-2: 32.8;SuSa: 22.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030413, HPA030414, HPA030415" Enhanced Supported "Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA030413: AB_10601455, HPA030414: AB_10670042, HPA030415: AB_10669598" "unprognostic (8.33e-2)" "unprognostic (8.79e-3)" "unprognostic (3.15e-3)" "unprognostic (6.94e-5)" "unprognostic (1.49e-1)" "unprognostic (2.92e-2)" "unprognostic (1.11e-3)" "unprognostic (1.10e-1)" "unprognostic (7.56e-3)" "unprognostic (9.52e-4)" "unprognostic (1.43e-2)" "unprognostic (3.12e-1)" "unprognostic (4.53e-3)" "unprognostic (3.59e-3)" "unprognostic (6.00e-2)" "unprognostic (3.61e-2)" "unprognostic (2.76e-2)" 4.7 1.9 1.1 1.7 1.2 0.8 2.7 1.7 1.6 8.6 0.8 1.9 1.7 2.9 8.7 1.9 3.1 6.6 2.0 1.5 1.6 8.4 0.9 4.6 1.7 0.4 0.2 10.4 3.8 3.0 0.8 25.9 0.5 3.9 2.3 1.4 0.8 2.2 4.9 2.1 1.8 1.4 0.1 12.6 2.1 77.5 1.1 3.8 2.9 1.6 0.9 5.4 3.0 0.8 0.2 0.2 30.4 3.1 6.3 10.5 4.9 2.2 5.1 2.5 5.3 32.8 0.2 0.2 1.0 0.4 1.7 1.4 0.1 0.8 3.7 1.0 1.8 0.1 2.9 0.2 1.1 0.1 0.1 12.6 0.6 2.7 0.2 0.3 7.8 0.5 0.8 2.5 4.1 0.5 0.5 0.3 9.6 0.4 1.4 0.1 2.7 0.2 0.0 2.9 2.9 11.9 0.1 2.8 0.5 22.6 0.2 0.1 1.3 0.5 13.1 10.1 0.4 0.2 0.1 0.1 5.0 0.3 1.1 0.7 0.2 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 3.0 0.1 0.0 0.2 0.0 0.0 1.1 1.2 1.7 1.6 1.5 1.6 0.4 0.2 0.5 0.1 1.1 0.8 8.3 0.0 1.9 6.2 0.1 1.9 1.3 0.2 0.0 1.5 0.9 0.5 1.8 0.0 0.7 1.8 20.9 14.9 0.0 0.0 0.0 1.1 536.8 0.5 14.6 7.9 0.0 0.0 7.1 2.7 2.7 16.1 0.0 0.4 0.0 25.8 4.2 0.2 2.1 0.0 34.4 0.1 0.0 0.3 0.4 488.0 18.3 0.5 0.0 12.2 0.0 0.2 0.0 24.6 3.6 0.7 0.0 14.3 0.1 4.7 0.0 3.8 0.0 0.8 0.0 11.0 5.4 14.3 3.7 0.8 1.4 6.6 0.3 23.7 0.0 1.3 ARHGAP29 PARG1 ENSG00000137962 "Rho GTPase activating protein 29" Q52LW3 1 94148988-94275068 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 440.8;Endothelial cells: 298.6;Prostatic glandular cells: 593.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 12 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "A-431: 118.8;hTERT-HME1: 100.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026534 Approved Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Centrosome" "Plasma membrane, Cytosol" "HPA026534: AB_1844998" "unprognostic (2.49e-1)" "unprognostic (1.52e-3)" "unprognostic (3.16e-2)" "prognostic unfavorable (6.26e-5)" "unprognostic (8.53e-2)" "unprognostic (2.94e-2)" "unprognostic (1.23e-1)" "unprognostic (1.11e-1)" "unprognostic (8.02e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (9.63e-4)" "unprognostic (4.42e-1)" "unprognostic (2.36e-2)" "unprognostic (3.81e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (4.61e-3)" 32.9 3.7 7.0 2.8 5.5 0.1 30.3 22.5 8.0 8.8 7.3 9.4 2.1 7.4 5.3 4.5 10.2 6.5 19.2 4.6 5.5 23.7 16.8 27.1 4.9 6.8 6.1 10.2 7.4 6.5 6.2 17.4 7.1 11.2 3.2 14.9 12.1 7.0 11.6 14.7 6.4 5.6 6.4 21.7 10.4 5.8 8.6 3.0 22.8 12.7 2.8 8.0 9.3 5.1 118.8 4.8 7.0 0.1 26.7 57.5 24.5 38.6 62.9 31.0 45.1 13.7 5.4 0.0 85.2 76.5 36.3 24.8 0.2 27.4 63.9 0.1 4.1 0.4 6.6 7.6 2.7 0.0 0.0 11.7 5.4 23.7 100.9 36.4 88.0 0.1 0.0 0.0 32.1 4.7 2.2 0.1 9.0 0.6 82.1 1.4 5.6 0.0 82.7 10.8 0.1 1.5 24.1 20.5 2.0 26.5 5.6 0.4 84.2 20.0 26.2 29.7 32.3 0.1 0.1 0.2 3.7 0.0 0.9 0.0 0.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 7.0 5.5 22.5 8.0 4.6 5.5 6.8 6.1 7.1 6.4 8.6 5.1 440.8 51.3 18.4 26.4 2.9 23.5 239.2 31.7 4.6 16.0 87.3 46.1 26.0 31.5 39.6 130.6 18.8 29.5 2.0 0.9 54.8 83.5 94.1 36.9 11.4 298.6 0.0 3.2 11.3 17.2 102.6 63.6 20.9 106.2 3.8 13.8 177.1 56.1 3.0 92.5 24.1 1.0 6.1 13.6 17.9 24.4 24.5 6.2 26.6 208.9 2.5 94.2 0.0 2.0 3.5 55.7 0.1 21.8 0.1 593.9 0.1 78.1 12.5 81.2 190.7 58.2 127.8 80.3 116.5 1.7 17.2 14.1 4.1 11.1 1.6 146.9 ARHGAP33 "FLJ39019, SNX26, TCGAP" ENSG00000004777 "Rho GTPase activating protein 33" O14559 19 35774532-35788822 "Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.4;Cone photoreceptor cells: 25.0;Horizontal cells: 20.2;Oligodendrocytes: 22.7;Rod photoreceptor cells: 33.7;Spermatocytes: 22.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 58.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030117, HPA030118" Supported Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Actin filaments, Cytosol" "HPA030117: AB_10599306, HPA030118: AB_10601238" "unprognostic (1.44e-3)" "unprognostic (3.40e-2)" "unprognostic (1.07e-1)" "unprognostic (3.33e-2)" "unprognostic (2.66e-1)" "unprognostic (2.82e-3)" "unprognostic (3.61e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-1)" "unprognostic (2.99e-2)" "unprognostic (2.97e-3)" "unprognostic (2.40e-2)" "prognostic unfavorable (3.09e-8)" "unprognostic (5.70e-2)" "unprognostic (2.66e-1)" "unprognostic (1.38e-1)" "unprognostic (1.19e-2)" 7.7 8.7 24.3 4.2 28.8 20.5 10.9 14.3 39.1 20.4 8.2 11.2 4.0 13.9 1.3 8.1 17.1 2.8 6.9 30.0 21.0 10.1 5.6 6.8 5.8 19.9 16.5 26.9 11.9 4.2 33.6 1.6 18.0 12.5 1.3 9.9 7.4 3.3 3.4 9.8 9.2 2.0 15.2 11.1 10.4 39.6 19.5 11.7 18.0 1.3 2.2 9.4 13.7 22.1 9.0 5.6 15.5 11.7 0.6 1.5 1.2 7.2 0.9 2.7 1.9 2.3 6.6 5.2 2.6 2.1 2.3 2.4 1.9 2.0 1.0 16.4 3.6 7.6 8.6 2.1 0.7 2.7 58.1 2.2 0.4 2.1 0.8 2.2 1.6 20.4 3.7 22.1 2.4 6.8 18.8 7.4 3.5 3.4 2.5 25.4 2.5 2.5 1.2 1.4 15.4 9.4 3.2 5.7 1.1 1.9 8.3 7.5 3.1 11.0 10.6 5.8 8.5 19.5 4.0 5.2 4.0 8.9 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.3 28.8 14.3 39.1 30.0 21.0 19.9 16.5 18.0 15.2 19.5 22.1 2.7 0.0 1.1 7.8 1.0 1.7 1.0 1.0 4.6 27.4 4.8 4.7 2.3 2.8 2.7 1.8 25.0 0.7 5.1 1.4 0.0 0.4 11.4 6.1 4.8 1.6 3.5 6.5 12.1 0.7 1.0 3.5 3.6 2.5 5.1 7.3 1.1 1.5 1.2 20.2 11.3 2.3 2.0 0.8 1.9 8.9 4.1 0.7 0.0 1.9 0.2 7.3 0.0 19.1 22.7 0.7 0.6 3.0 2.2 0.6 0.3 0.2 4.2 33.7 0.0 4.6 3.1 22.2 6.2 4.2 1.7 0.4 3.6 7.2 2.8 0.6 ARHGAP36 FLJ30058 ENSG00000147256 "Rho GTPase activating protein 36" Q6ZRI8 X 131058346-131089885 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "adrenal gland: 105.4;brain: 144.3;pituitary gland: 176.9" "Cell type enhanced" "Detected in some" "Astrocytes: 1.0;Breast glandular cells: 2.7;Oligodendrocyte precursor cells: 1.0;Skeletal myocytes: 1.5" "Cancer enriched" "Detected in some" 21 "thyroid cancer: 62.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 161 "SH-SY5Y: 176.9" "Region enhanced" "Detected in many" "hypothalamus: 89.4" "Low region specificity" "Detected in many" "HPA002064, HPA076209" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" Yes NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" Nucleoplasm "Vesicles, Plasma membrane" "HPA002064: AB_1078891, HPA076209: " "unprognostic (2.92e-2)" "unprognostic (7.71e-9)" "unprognostic (2.19e-1)" "unprognostic (8.15e-2)" "unprognostic (1.67e-1)" "unprognostic (1.78e-1)" "unprognostic (2.73e-1)" "unprognostic (1.40e-2)" "unprognostic (1.34e-2)" "unprognostic (2.31e-1)" 0.2 105.4 20.1 0.0 3.7 0.0 1.4 0.8 3.2 1.6 0.8 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.1 13.5 132.5 0.0 0.0 0.0 0.0 35.0 46.1 0.0 0.0 0.0 176.9 0.1 144.3 0.2 0.1 0.0 0.2 0.0 6.6 0.1 0.0 0.0 4.7 0.0 0.1 0.8 52.1 0.4 0.1 1.1 0.0 0.0 0.1 10.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 176.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 3.7 0.8 3.2 13.5 132.5 35.0 46.1 144.3 4.7 52.1 10.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ARHGAP40 "C20orf95, dJ1100H13.4" ENSG00000124143 "Rho GTPase activating protein 40" Q5TG30 20 38601934-38651035 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Group enriched" "Detected in many" 4 "breast: 32.4;epididymis: 35.7;esophagus: 28.7;skin 1: 45.3" "Cell type enhanced" "Detected in some" "Breast glandular cells: 14.7;Breast myoepithelial cells: 8.6;Club cells: 4.3;Collecting duct cells: 3.7;Early spermatids: 7.2;Late spermatids: 4.3;Respiratory ciliated cells: 3.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.3;HBEC3-KT: 13.6;RPTEC TERT1: 11.7;SK-BR-3: 12.7;T-47d: 15.4" "Not detected" "Not detected" "HPA042636, HPA042840" Uncertain Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" No NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 35: Glandular cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA042636: AB_10962149, HPA042840: AB_10963929" "unprognostic (9.89e-3)" "unprognostic (2.57e-1)" "unprognostic (1.93e-1)" "unprognostic (1.24e-3)" "unprognostic (3.11e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-3)" "unprognostic (1.69e-1)" "unprognostic (3.09e-2)" "unprognostic (4.35e-2)" "unprognostic (5.63e-3)" "unprognostic (2.52e-1)" "prognostic unfavorable (2.89e-4)" "unprognostic (2.24e-1)" "unprognostic (7.42e-2)" "unprognostic (1.26e-1)" "unprognostic (1.54e-1)" 0.1 0.0 0.3 0.0 1.3 0.0 32.4 0.1 0.6 3.2 0.2 0.0 1.7 0.7 35.7 28.7 0.1 0.1 0.0 0.2 0.3 5.6 0.1 0.8 0.0 0.3 1.8 0.0 0.3 0.0 0.0 0.0 0.8 4.6 0.0 0.0 3.6 7.9 0.4 45.3 0.0 0.0 0.2 0.0 4.6 2.7 0.6 0.0 0.9 0.0 3.7 3.2 7.4 0.2 4.5 0.0 0.0 0.0 0.0 0.0 8.3 0.1 0.0 0.0 0.1 0.2 0.9 0.0 3.6 0.0 0.0 0.0 0.0 13.6 0.2 0.0 0.0 0.2 0.0 3.4 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.5 0.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.7 0.0 0.0 0.0 0.0 12.7 0.0 1.6 15.4 0.5 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.1 0.6 0.2 0.3 0.3 1.8 0.8 0.2 0.6 0.2 0.1 0.0 1.5 0.7 0.0 0.3 0.0 1.8 0.0 0.0 14.7 8.6 0.1 0.0 4.3 3.7 0.0 0.0 0.2 0.0 0.0 0.0 7.2 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.4 3.4 0.0 0.0 0.0 0.3 0.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARHGEF11 "GTRAP48, KIAA0380, PDZ-RHOGEF" ENSG00000132694 "Rho guanine nucleotide exchange factor 11" O15085 1 156934840-157045742 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.6;Cone photoreceptor cells: 93.8;Excitatory neurons: 102.4;Inhibitory neurons: 122.5;Oligodendrocyte precursor cells: 78.4;Rod photoreceptor cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "WM-115: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011026, HPA012037, HPA014658" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA011026: AB_1850426, HPA012037: AB_1850430, HPA014658: AB_1850428" "unprognostic (2.19e-1)" "unprognostic (9.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.17e-1)" "unprognostic (2.00e-1)" "unprognostic (4.94e-3)" "unprognostic (3.30e-2)" "unprognostic (9.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.72e-4)" "unprognostic (3.38e-1)" "unprognostic (2.41e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (4.73e-2)" 10.9 10.9 10.3 9.5 8.6 4.3 8.1 4.1 22.6 10.0 0.8 12.3 13.1 12.0 9.6 11.5 10.3 10.2 12.1 9.4 10.2 7.2 6.3 11.4 5.3 12.7 11.1 13.2 9.9 25.0 12.2 11.1 12.0 9.2 11.2 17.6 8.6 11.6 12.3 10.0 14.9 13.3 4.0 9.3 10.7 19.2 16.9 3.6 13.0 11.2 5.7 10.4 8.1 11.1 13.5 26.6 22.0 16.9 28.5 14.6 25.0 13.4 19.4 20.0 14.6 17.9 14.0 1.8 22.6 23.0 15.3 14.4 15.0 13.5 10.8 19.6 9.3 6.7 15.9 11.5 16.4 13.7 23.0 22.7 14.4 18.3 14.2 14.9 14.5 5.7 11.1 1.2 13.3 17.4 3.5 7.2 27.6 21.0 16.0 0.5 10.9 7.4 9.5 21.9 4.2 25.1 28.3 22.6 23.3 18.8 20.3 30.3 22.4 20.6 12.9 18.3 13.7 18.7 12.2 1.3 13.1 1.8 69.7 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.9 0.0 0.4 0.0 0.0 0.2 10.3 8.6 4.1 22.6 9.4 10.2 12.7 11.1 12.0 4.0 16.9 11.1 6.2 3.2 4.2 68.6 0.5 1.1 2.8 0.4 0.0 48.0 5.0 5.8 15.3 7.2 1.6 1.8 93.8 1.8 0.0 26.0 1.9 1.1 8.6 7.7 10.9 5.0 5.4 0.4 102.4 1.6 0.6 5.5 10.2 7.8 8.9 6.6 5.3 5.2 4.0 21.9 122.5 7.3 0.0 8.8 3.9 10.5 4.7 7.1 1.8 37.5 6.8 9.7 0.0 78.4 47.2 1.2 10.8 4.5 2.9 4.0 10.6 1.3 1.4 58.7 0.0 6.7 6.9 3.1 4.8 1.8 2.0 1.5 0.9 9.2 9.8 3.3 ARHGEF12 "KIAA0382, LARG" ENSG00000196914 "Rho guanine nucleotide exchange factor 12" Q9NZN5 11 120336413-120489937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018911, CAB025581" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB025581: , HPA018911: AB_1845003" "unprognostic (1.55e-1)" "unprognostic (1.29e-1)" "unprognostic (6.91e-3)" "unprognostic (1.28e-1)" "unprognostic (7.28e-2)" "unprognostic (5.39e-2)" "unprognostic (1.56e-1)" "unprognostic (5.55e-2)" "unprognostic (4.79e-2)" "unprognostic (7.77e-2)" "unprognostic (4.34e-3)" "unprognostic (4.78e-2)" "prognostic favorable (5.43e-6)" "unprognostic (1.29e-1)" "unprognostic (4.38e-2)" "unprognostic (2.13e-1)" "unprognostic (1.48e-1)" 25.6 30.6 27.2 14.3 26.9 11.4 31.9 26.8 32.1 32.9 26.4 27.6 25.0 27.8 25.4 27.6 29.3 28.4 40.3 30.9 23.0 67.4 66.4 36.7 11.9 17.8 25.6 25.2 26.1 68.4 14.6 42.9 17.3 26.5 29.1 47.7 25.0 30.9 32.2 49.5 25.5 30.3 20.1 21.5 32.2 9.7 35.9 13.5 51.5 31.8 18.7 28.7 22.0 19.3 38.1 31.6 41.9 39.8 55.0 54.5 16.7 43.8 49.8 26.1 33.1 37.5 27.2 3.2 51.7 79.8 46.6 27.5 54.1 56.0 51.3 31.1 25.8 61.8 34.0 29.2 49.2 0.1 43.7 52.4 39.7 57.8 63.8 58.0 80.7 32.7 52.4 122.5 67.0 26.6 0.1 0.1 11.4 49.3 26.1 13.4 47.4 11.9 65.1 66.1 30.0 36.4 61.5 51.0 16.2 25.0 43.1 5.1 80.1 57.2 24.2 37.6 32.4 35.1 15.4 20.2 23.6 7.9 44.2 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 27.2 26.9 26.8 32.1 30.9 23.0 17.8 25.6 17.3 20.1 35.9 19.3 86.2 73.7 88.4 274.9 8.6 90.5 69.1 47.2 42.1 134.6 55.1 26.9 87.6 68.6 57.8 97.5 185.6 16.7 11.5 59.7 35.2 45.6 6.4 61.4 55.7 94.0 37.8 69.7 239.0 50.9 10.4 44.0 34.7 140.3 11.4 44.9 85.6 118.3 7.3 90.9 192.4 39.6 18.3 31.2 25.6 14.8 29.8 18.2 51.6 118.0 8.7 41.0 13.4 143.2 55.0 53.5 52.1 33.4 9.3 85.6 48.1 76.3 48.7 80.9 26.3 58.4 60.3 16.3 13.8 55.3 85.1 28.7 16.1 43.1 41.3 99.1 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARHGEF26 "DKFZP434D146, SGEF" ENSG00000114790 "Rho guanine nucleotide exchange factor 26" Q96DR7 3 154121003-154257827 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 339.7;Astrocytes: 248.8" "Cancer enhanced" "Detected in all" "prostate cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-251 MG: 26.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017722, HPA049195" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017722: AB_1856800, HPA049195: AB_2680671" "unprognostic (1.41e-1)" "unprognostic (1.43e-3)" "unprognostic (3.55e-1)" "unprognostic (7.99e-3)" "unprognostic (2.82e-1)" "unprognostic (9.42e-3)" "prognostic favorable (9.74e-4)" "unprognostic (7.06e-2)" "unprognostic (1.16e-1)" "unprognostic (6.01e-5)" "unprognostic (1.44e-3)" "unprognostic (4.36e-2)" "unprognostic (2.22e-1)" "unprognostic (5.53e-3)" "unprognostic (3.11e-1)" "unprognostic (1.07e-1)" "unprognostic (5.24e-3)" 8.0 2.1 5.8 1.8 5.7 0.3 6.0 4.1 5.3 5.0 7.7 18.3 7.3 4.3 1.2 7.4 6.2 5.5 3.2 4.6 5.0 1.7 15.5 16.3 0.3 5.9 7.3 3.9 6.0 9.9 1.7 3.4 5.8 3.4 2.6 7.1 3.1 4.8 0.4 6.2 6.6 7.1 5.4 0.8 8.7 5.1 6.1 0.8 3.1 1.4 0.9 5.1 6.4 4.8 8.5 3.7 10.6 6.8 5.1 1.4 0.3 0.3 0.0 3.1 4.3 6.5 0.8 5.0 0.5 0.6 4.9 8.9 6.7 4.4 3.9 0.0 8.8 0.1 2.6 1.5 4.7 1.6 0.2 1.3 0.4 4.0 0.5 1.8 0.6 5.4 0.0 0.0 2.0 8.1 2.0 0.1 6.7 2.4 3.0 0.0 12.9 0.0 0.7 4.1 3.2 1.1 1.7 14.4 1.5 4.6 10.1 0.5 0.0 1.1 5.3 0.1 26.6 4.5 0.7 0.0 2.5 0.0 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 5.7 4.1 5.3 4.6 5.0 5.9 7.3 5.8 5.4 6.1 4.8 5.0 339.7 26.8 248.8 1.7 19.5 9.0 2.7 17.6 11.6 54.2 6.6 1.8 20.0 10.8 3.7 4.2 1.8 4.3 1.5 0.0 2.2 11.9 4.7 4.5 4.3 0.0 2.7 4.2 2.5 1.1 12.0 14.3 2.1 5.1 3.6 8.6 60.8 0.6 5.0 10.1 7.9 6.1 2.5 3.4 3.4 10.5 1.3 3.6 7.5 2.7 58.1 12.3 41.7 5.1 2.0 6.9 18.8 0.7 7.5 21.4 0.1 14.9 47.8 0.0 14.1 3.7 4.7 37.0 11.7 23.7 6.2 4.7 2.5 8.1 5.7 ARHGEF28 "p190RhoGEF, RGNEF, RIP2" ENSG00000214944 "Rho guanine nucleotide exchange factor 28" Q8N1W1 5 73626158-73941993 "Predicted intracellular proteins" Differentiation "Guanine-nucleotide releasing factor, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 31.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 73.1;Granulosa cells: 83.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 97.8;LHCN-M2: 92.2;TIME: 59.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037602 Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Microtubules, Cytosol" "Plasma membrane" "HPA037602: AB_10672282" "unprognostic (1.97e-1)" "prognostic favorable (5.31e-4)" "unprognostic (7.66e-2)" "unprognostic (1.53e-1)" "unprognostic (3.33e-3)" "unprognostic (3.18e-2)" "unprognostic (1.42e-1)" "unprognostic (1.05e-1)" "unprognostic (5.37e-1)" "unprognostic (3.63e-1)" "unprognostic (2.62e-1)" "unprognostic (3.04e-1)" "prognostic favorable (1.91e-6)" "unprognostic (1.07e-1)" "unprognostic (1.55e-2)" "unprognostic (1.62e-2)" "prognostic favorable (8.98e-4)" 4.8 23.9 4.5 1.1 4.7 0.0 7.5 0.4 5.1 3.9 0.0 3.3 3.2 4.1 2.5 6.4 9.8 5.3 1.9 5.0 4.3 31.5 6.4 7.3 0.4 1.6 2.0 19.0 20.7 1.2 6.0 0.5 3.2 5.0 3.7 6.0 19.2 3.6 0.9 14.8 2.5 3.5 1.4 2.8 21.8 1.5 3.2 4.0 13.6 0.9 2.9 3.7 6.6 2.8 30.1 21.0 0.1 2.6 2.6 3.6 0.0 10.8 21.5 13.5 13.3 6.3 12.8 0.1 22.5 3.7 30.4 10.0 1.4 17.4 20.2 0.2 3.1 0.6 3.3 27.2 20.9 0.0 0.0 3.3 7.0 21.0 97.8 25.2 44.4 0.6 0.0 0.0 92.2 2.8 0.0 0.0 0.2 7.9 8.5 0.0 5.5 3.7 36.4 18.0 2.0 3.9 5.3 0.8 0.6 0.0 4.6 0.1 59.8 6.6 9.2 0.5 10.3 1.1 0.0 0.2 10.1 1.4 4.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 4.5 4.7 0.4 5.1 5.0 4.3 1.6 2.0 3.2 1.4 3.2 2.8 9.1 28.9 16.4 3.9 0.2 25.7 14.1 14.1 40.5 4.9 7.5 11.0 2.0 24.3 15.5 31.3 0.0 0.3 2.1 3.7 15.6 13.0 9.6 32.7 1.7 12.8 11.4 2.7 73.1 11.3 0.3 3.1 35.7 12.6 1.3 83.2 2.2 7.3 0.3 13.5 34.5 10.7 40.7 0.3 0.9 2.6 10.2 3.3 1.8 32.8 0.6 26.8 1.0 34.7 15.2 26.3 4.6 5.7 1.2 16.0 3.9 26.7 50.4 1.6 6.6 0.5 7.0 1.0 1.3 20.4 25.6 0.1 1.2 32.3 6.7 17.3 ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" 21.0 47.2 9.6 5.3 11.1 1.6 18.5 10.0 9.2 24.8 6.2 14.5 3.7 18.9 12.2 3.5 13.2 14.8 12.3 8.9 11.1 10.1 26.9 14.2 2.3 13.5 10.5 19.3 24.0 10.7 9.0 6.5 10.5 12.3 6.2 2.8 20.2 18.6 10.5 7.4 7.9 9.7 10.1 27.8 9.5 4.3 12.1 3.1 15.8 6.1 1.7 13.8 13.3 12.1 3.3 2.9 30.8 5.8 24.5 37.1 1.1 11.4 28.1 12.1 9.4 1.4 7.5 0.0 1.8 20.9 12.2 5.0 2.6 3.7 4.3 6.6 1.1 4.6 3.4 9.0 3.5 3.0 16.5 15.5 2.4 10.3 3.1 22.6 0.0 0.0 1.4 1.3 9.6 0.3 0.0 8.6 8.1 0.8 0.5 1.0 23.2 1.4 7.6 4.1 0.7 11.6 6.4 0.6 8.9 6.0 2.7 10.1 5.9 25.4 17.5 11.9 5.9 2.6 0.0 0.0 8.8 4.2 7.5 0.0 1.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.0 0.4 9.6 11.1 10.0 9.2 8.9 11.1 13.5 10.5 10.5 10.1 12.1 12.1 12.7 6.4 5.0 32.0 2.5 4.8 8.0 5.8 1.8 9.2 6.6 11.3 13.4 47.1 3.2 14.7 0.0 1.4 0.5 10.0 19.6 21.2 1.0 17.6 13.1 11.0 7.8 1.7 0.3 10.2 0.9 20.4 18.3 3.5 38.0 11.6 8.2 31.5 14.1 5.0 6.2 9.1 4.1 46.9 14.6 2.3 24.2 22.0 23.2 17.8 23.6 24.6 1.0 21.1 8.9 16.4 6.6 24.0 3.1 6.3 1.0 7.1 1.7 6.8 26.3 18.6 21.9 3.1 2.8 0.6 4.4 1.2 3.5 14.6 18.7 6.1 ARHGEF5 "GEF5, P60, TIM, TIM1" ENSG00000050327 "Rho guanine nucleotide exchange factor 5" Q12774 7 144355288-144380632 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 47.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 61.7;Glandular and luminal cells: 47.4;Paneth cells: 53.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 29.4;CAPAN-2: 21.9;HaCaT: 16.7;hTCEpi: 18.0;RPTEC TERT1: 17.5;WM-115: 17.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA020980, HPA029504, HPA044188, HPA045619, HPA045699" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA020980: AB_1845007, HPA029504: AB_10602231, HPA044188: AB_2678850, HPA045619: AB_2679393, HPA045699: AB_2679423" "unprognostic (1.45e-1)" "unprognostic (2.05e-1)" "unprognostic (1.87e-2)" "unprognostic (1.94e-1)" "unprognostic (9.45e-2)" "unprognostic (2.69e-2)" "unprognostic (9.95e-3)" "unprognostic (9.21e-2)" "unprognostic (1.05e-2)" "unprognostic (2.27e-1)" "unprognostic (3.67e-2)" "unprognostic (2.12e-1)" "prognostic favorable (3.28e-7)" "unprognostic (4.67e-2)" "unprognostic (4.86e-1)" "unprognostic (2.36e-1)" "unprognostic (7.76e-2)" 5.1 2.6 1.8 1.6 2.4 2.4 12.3 1.5 1.7 11.5 5.7 16.4 10.1 3.4 6.9 36.6 4.7 4.7 3.5 0.9 1.8 20.9 14.4 8.4 2.2 2.1 2.7 5.6 19.0 7.3 9.5 3.2 1.8 14.7 5.6 1.8 18.1 2.0 0.7 47.1 13.1 1.2 1.3 3.8 13.8 2.0 2.0 1.8 24.0 0.2 3.1 5.3 17.6 1.4 29.4 3.3 0.0 0.0 0.0 0.0 8.7 3.8 2.3 1.5 1.9 11.5 21.9 0.1 10.3 0.9 0.3 16.7 0.0 10.6 1.5 0.1 3.8 0.0 4.2 0.8 3.1 0.0 0.0 5.5 18.0 0.7 9.9 4.8 0.1 0.0 0.0 0.0 1.5 9.7 0.1 0.0 4.5 7.9 5.2 1.1 0.0 0.4 17.5 1.3 0.1 0.1 11.5 13.4 5.1 2.3 6.8 0.3 0.2 0.5 0.8 0.0 0.1 0.0 0.1 0.1 0.6 0.0 17.7 0.0 0.0 0.0 0.3 0.0 0.4 0.8 0.8 0.7 0.0 0.9 0.9 0.2 0.3 0.0 0.0 0.0 1.5 0.1 1.8 2.4 1.5 1.7 0.9 1.8 2.1 2.7 1.8 1.3 2.0 1.4 3.0 6.4 14.8 0.3 2.3 18.5 37.3 9.4 26.2 0.0 17.5 18.7 1.4 11.5 12.1 22.0 4.2 11.8 1.4 61.7 5.9 14.8 2.3 28.9 5.5 1.6 9.6 2.7 0.0 16.5 15.2 3.6 37.2 47.4 0.0 4.0 1.8 7.5 1.8 0.0 0.0 24.0 6.1 0.3 1.9 0.6 1.5 1.2 5.4 0.0 0.0 2.7 0.0 0.5 0.1 27.7 53.7 1.5 3.1 14.3 42.0 5.4 13.5 3.1 0.0 1.1 1.8 0.7 1.5 28.7 16.8 14.2 2.5 1.1 23.5 33.6 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARID4A "RBBP1, RBP-1, RBP1" ENSG00000032219 "AT-rich interaction domain 4A" P29374 14 58298504-58373887 "Predicted intracellular proteins, Transcription factors" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048899 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "HPA048899: " "unprognostic (1.57e-1)" "unprognostic (9.39e-2)" "unprognostic (5.17e-2)" "unprognostic (2.69e-1)" "unprognostic (3.70e-2)" "prognostic favorable (1.91e-4)" "unprognostic (2.71e-1)" "prognostic favorable (7.82e-4)" "unprognostic (2.08e-2)" "unprognostic (6.92e-2)" "unprognostic (3.27e-1)" "unprognostic (3.72e-2)" "unprognostic (9.32e-2)" "unprognostic (2.32e-1)" "unprognostic (2.64e-1)" "unprognostic (4.11e-2)" "unprognostic (3.52e-2)" 9.8 6.9 8.6 11.1 9.2 34.7 9.1 14.8 10.0 8.6 8.9 7.7 8.8 9.5 6.8 7.4 6.8 9.0 8.7 8.0 11.7 9.4 18.7 10.3 14.9 7.9 7.7 12.5 7.4 9.8 5.4 9.8 7.6 8.6 8.8 14.0 6.7 7.6 5.4 8.7 9.1 8.2 6.8 14.0 8.9 6.9 12.3 14.5 10.6 6.3 11.2 8.4 7.5 10.7 8.5 7.0 19.2 9.5 9.3 11.2 9.7 9.9 8.4 6.6 10.4 8.3 13.1 20.4 10.3 8.4 6.3 9.6 8.6 4.8 9.6 14.3 5.5 9.2 8.2 8.0 5.6 19.7 12.8 8.4 5.2 6.4 6.6 10.5 10.6 11.6 10.7 16.3 7.1 11.5 14.3 17.7 3.8 8.2 8.7 14.5 16.6 6.1 7.1 14.9 16.5 14.3 16.9 8.4 12.0 9.4 14.3 17.8 15.3 11.2 8.7 9.1 4.6 5.3 4.2 18.3 6.7 12.3 5.8 65.8 19.5 59.1 20.6 20.1 23.3 31.5 25.3 22.1 14.9 42.3 27.0 26.5 109.4 29.1 40.8 19.8 19.8 10.1 8.6 9.2 14.8 10.0 8.0 11.7 7.9 7.7 7.6 6.8 12.3 10.7 57.7 83.3 100.9 68.9 73.5 38.4 21.2 22.1 64.3 111.0 29.5 35.8 55.0 24.3 32.3 27.6 52.1 19.9 74.0 33.0 19.6 23.3 18.2 40.5 37.6 47.1 22.8 45.8 94.2 21.7 21.3 40.1 26.0 52.6 65.2 39.9 37.5 41.9 34.7 112.7 78.6 35.5 20.3 47.7 49.5 8.8 36.4 59.3 26.6 63.7 75.8 63.9 49.4 86.5 91.4 24.9 38.6 36.1 55.1 20.9 43.4 14.9 11.2 64.2 19.7 40.0 43.0 38.6 33.8 55.4 33.4 20.4 77.0 34.1 32.9 17.7 ARID5B "FLJ21150, MRF2" ENSG00000150347 "AT-rich interaction domain 5B" Q14865 10 61901684-62096944 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 87.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 968.2;Syncytiotrophoblasts: 920.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 115.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015037 Uncertain Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Cytosol" "HPA015037: AB_1845015" "unprognostic (3.31e-1)" "unprognostic (1.99e-2)" "unprognostic (2.94e-2)" "unprognostic (1.86e-1)" "unprognostic (1.17e-1)" "unprognostic (5.60e-2)" "unprognostic (1.50e-2)" "unprognostic (4.90e-2)" "unprognostic (3.90e-1)" "unprognostic (6.03e-2)" "unprognostic (1.97e-1)" "unprognostic (5.75e-1)" "unprognostic (1.20e-2)" "unprognostic (1.15e-1)" "unprognostic (2.58e-1)" "unprognostic (1.94e-1)" "unprognostic (3.93e-2)" 50.0 8.1 2.9 21.2 5.8 6.9 34.3 3.2 11.3 37.2 20.7 17.5 10.2 39.0 4.6 20.2 20.6 39.3 18.3 4.4 1.6 21.4 8.3 18.3 18.8 7.8 6.9 17.5 6.2 13.3 10.0 21.0 11.4 18.3 11.7 4.1 15.8 10.2 87.2 18.1 14.2 42.5 0.9 16.9 11.5 6.9 9.0 13.1 7.8 11.9 16.7 30.9 19.6 9.7 2.2 0.9 6.0 14.7 13.0 34.0 1.2 42.9 115.2 29.9 23.3 52.7 2.3 3.9 10.1 41.4 4.3 14.3 20.6 6.5 36.0 13.7 6.1 2.1 10.4 13.5 23.9 0.6 25.2 43.3 3.4 17.6 20.2 26.2 3.9 7.5 1.9 5.7 9.9 7.7 14.4 1.1 1.1 10.2 13.5 17.7 9.8 1.1 20.1 23.9 3.3 4.4 19.2 10.6 12.8 13.1 8.7 0.7 3.3 16.5 22.0 25.1 10.9 0.4 0.0 11.4 14.3 0.8 5.4 9.6 1.2 0.8 13.3 2.8 1.8 37.5 19.7 11.8 2.2 41.2 12.8 8.4 2.2 12.3 8.2 1.0 30.9 5.4 2.9 5.8 3.2 11.3 4.4 1.6 7.8 6.9 11.4 0.9 9.0 9.7 86.2 131.4 70.7 54.5 199.8 968.2 453.9 111.3 105.9 54.4 112.8 96.6 72.8 27.1 96.3 51.5 0.0 187.8 89.1 7.5 99.7 56.1 31.7 164.7 231.0 134.1 36.4 5.2 167.8 14.6 150.7 343.6 21.4 457.7 24.6 37.6 119.2 7.4 51.0 74.0 181.9 18.7 22.4 44.1 162.4 20.1 151.6 43.6 138.7 34.7 39.0 17.2 58.7 74.4 155.8 41.1 25.2 60.5 234.5 193.7 5.4 304.8 38.4 3.6 131.5 496.3 463.9 8.2 5.8 65.7 477.8 920.4 178.2 24.3 41.7 233.9 ARL13A ARL13 ENSG00000174225 "ADP ribosylation factor like GTPase 13A" Q5H913 X 100969708-100990831 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "testis: 5.1" "Group enriched" "Detected in some" 29 "Early spermatids: 69.8;Late spermatids: 55.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 2.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037377, HPA037378" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "Actin filaments, Cytosol" "HPA037377: AB_2675442, HPA037378: AB_10670932" "unprognostic (4.40e-2)" "unprognostic (1.05e-1)" "unprognostic (1.02e-1)" "unprognostic (1.08e-2)" "unprognostic (1.93e-1)" "unprognostic (9.06e-3)" "unprognostic (2.58e-1)" "unprognostic (3.95e-2)" "unprognostic (1.82e-1)" "unprognostic (1.06e-1)" "unprognostic (1.18e-1)" "unprognostic (1.51e-2)" "unprognostic (4.50e-3)" "unprognostic (1.46e-1)" "unprognostic (2.46e-1)" "unprognostic (9.37e-4)" "unprognostic (2.14e-1)" 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.1 0.1 5.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.4 0.6 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.4 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.1 0.6 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 69.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 55.5 0.6 0.0 0.0 0.0 0.0 1.6 0.0 0.5 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ARL15 "ARFRP2, FLJ20051" ENSG00000185305 "ADP ribosylation factor like GTPase 15" Q9NXU5 5 53883942-54310582 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 441.6;Inhibitory neurons: 285.2;Microglial cells: 408.5;Oligodendrocyte precursor cells: 184.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044604, HPA063820" Uncertain Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus" "Plasma membrane, Cell Junctions" "HPA044604: AB_10960542, HPA063820: AB_2685131" "unprognostic (2.18e-1)" "unprognostic (4.32e-2)" "unprognostic (1.82e-2)" "unprognostic (2.41e-2)" "unprognostic (1.08e-1)" "unprognostic (3.70e-1)" "unprognostic (8.52e-3)" "unprognostic (1.16e-2)" "unprognostic (3.05e-2)" "unprognostic (6.56e-2)" "unprognostic (4.26e-3)" "unprognostic (3.86e-1)" "unprognostic (2.48e-3)" "unprognostic (1.35e-1)" "unprognostic (9.15e-2)" "unprognostic (5.60e-2)" "unprognostic (1.08e-1)" 14.0 12.5 6.6 5.6 7.5 1.9 13.0 5.6 10.0 17.7 7.2 10.6 11.9 16.0 7.6 9.8 8.2 14.5 14.0 8.5 7.1 17.9 9.8 7.6 6.3 5.8 6.2 5.7 5.0 3.2 8.5 22.3 6.0 10.0 10.9 7.6 10.5 6.8 3.3 11.3 9.9 16.6 6.1 8.2 8.3 9.3 6.8 10.6 8.4 11.7 8.0 13.6 8.8 6.2 3.2 5.5 8.5 15.6 7.0 7.8 11.8 10.2 15.1 9.4 20.7 21.1 8.0 32.0 14.9 9.1 11.0 7.7 13.2 14.1 12.4 3.2 13.9 36.9 7.1 2.8 2.5 4.5 43.8 10.0 10.1 15.8 9.5 14.2 20.8 7.0 32.4 5.3 6.5 7.7 7.5 4.3 3.0 1.6 3.9 6.2 10.4 0.8 12.8 30.3 11.3 7.1 13.1 6.7 7.9 15.6 8.6 4.7 11.4 5.7 9.6 5.4 6.7 1.8 1.7 34.8 9.9 10.6 9.5 1.1 1.8 2.2 1.3 1.4 0.7 1.0 0.9 0.9 2.4 0.7 0.9 0.7 3.5 0.7 1.2 0.3 2.3 1.2 6.6 7.5 5.6 10.0 8.5 7.1 5.8 6.2 6.0 6.1 6.8 6.2 44.5 3.2 7.7 33.6 6.5 9.7 7.9 5.8 8.0 5.1 4.8 5.8 7.5 5.7 4.5 12.9 14.6 52.5 5.2 7.5 21.5 3.2 3.4 4.1 6.9 35.1 20.9 8.6 441.6 4.9 4.9 8.5 6.6 5.1 2.5 3.2 26.0 4.9 8.4 1.7 285.2 7.6 18.3 8.7 8.7 1.5 4.4 12.5 1.8 408.5 5.0 3.2 6.2 184.5 104.7 6.9 7.6 3.8 4.7 5.4 5.7 10.0 3.9 3.0 6.6 3.6 5.3 1.0 3.5 5.9 10.1 42.7 8.9 24.4 7.1 8.4 ARL4C "ARL7, LAK" ENSG00000188042 "ADP ribosylation factor like GTPase 4C" P56559 2 234493041-234497081 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "dendritic cells: 610.9;Langerhans cells: 474.5;NK-cells: 437.7;T-cells: 349.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 149.4;RPTEC TERT1: 284.8;U-2197: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028927 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA028927: AB_10602387" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-3)" "prognostic unfavorable (2.90e-7)" "unprognostic (8.01e-3)" "unprognostic (3.35e-2)" "unprognostic (9.26e-2)" "unprognostic (2.68e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-2)" "unprognostic (3.17e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.69e-8)" "unprognostic (8.57e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.99e-5)" 15.1 10.6 15.4 31.7 14.6 65.0 17.3 17.8 18.6 11.4 45.3 9.1 6.6 5.8 9.5 23.2 11.9 31.8 5.1 13.1 21.9 12.2 12.8 16.1 55.3 21.9 17.1 2.1 5.5 10.8 7.4 16.5 21.3 10.3 11.2 9.7 21.6 5.4 1.5 24.1 13.2 5.9 12.8 51.0 13.6 1.2 18.5 74.0 3.7 1.7 32.1 25.5 18.0 13.8 32.3 97.4 12.0 1.6 10.4 3.0 31.6 3.2 13.8 3.8 6.6 45.4 60.4 0.1 8.0 7.7 109.0 23.5 12.0 66.4 4.1 30.4 4.2 0.0 0.6 0.6 10.7 0.1 2.8 6.4 42.2 36.6 21.2 149.4 6.4 78.4 0.4 102.4 16.4 4.4 93.7 0.3 12.6 22.5 21.9 0.3 54.1 18.0 284.8 35.2 44.1 8.1 1.1 7.1 4.7 18.2 0.9 1.9 14.8 60.0 23.2 168.2 61.6 51.1 19.7 1.6 101.9 0.1 32.0 79.8 1.2 27.4 86.7 1.6 85.6 18.1 60.0 69.5 10.3 18.3 53.5 59.1 2.2 61.2 0.9 55.2 83.8 30.0 15.4 14.6 17.8 18.6 13.1 21.9 21.9 17.1 21.3 12.8 18.5 13.8 12.3 73.7 15.9 8.8 63.6 124.8 120.7 18.4 145.1 156.6 40.4 64.6 10.9 67.2 27.0 14.7 8.4 30.0 610.9 2.3 0.0 19.6 7.8 73.9 19.2 23.4 1.8 6.1 15.5 5.7 5.4 23.7 19.9 186.3 27.8 1.1 11.0 3.4 31.4 107.7 103.0 2.5 0.0 208.4 474.5 6.5 0.3 182.1 42.7 6.5 41.8 32.2 437.7 6.0 2.5 16.5 0.1 0.0 132.6 60.4 0.1 0.9 4.7 13.1 0.0 7.0 19.3 0.7 1.9 65.4 42.9 14.6 349.8 0.4 1.2 46.6 ARMC12 "C6orf81, FLJ25390" ENSG00000157343 "Armadillo repeat containing 12" Q5T9G4 6 35737032-35749079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 64.2" "Group enriched" "Detected in some" 96 "Early spermatids: 503.3;Late spermatids: 1116.3" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.9;HSkMC: 6.1;MOLT-4: 4.8;U-698: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030895, HPA075457, HPA075777" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Plasma membrane" "HPA030895: AB_10602114, HPA075457: , HPA075777: " "unprognostic (1.94e-4)" "unprognostic (2.21e-1)" "unprognostic (3.24e-1)" "unprognostic (1.32e-2)" "unprognostic (2.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.12e-1)" "unprognostic (4.48e-1)" "unprognostic (3.52e-2)" "unprognostic (6.36e-4)" "unprognostic (8.99e-2)" "unprognostic (1.17e-12)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.09e-1)" 1.6 1.7 4.4 0.6 4.4 0.9 1.5 4.0 5.3 2.5 5.1 1.5 0.0 1.7 5.8 0.8 2.8 0.7 0.7 4.3 4.5 1.5 4.5 1.2 1.3 4.6 5.1 3.0 1.3 0.5 11.2 0.2 4.6 3.6 0.3 1.3 0.6 0.8 1.9 1.1 1.7 0.7 4.3 2.8 1.2 64.2 4.3 3.0 2.4 0.5 0.7 1.1 1.7 4.5 0.0 0.3 2.1 2.7 4.9 2.3 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.5 0.1 0.1 0.8 0.1 0.6 0.1 0.1 1.2 0.6 0.3 0.1 0.0 2.4 0.0 0.0 6.1 1.5 0.1 0.9 2.5 0.5 2.0 0.0 3.2 0.8 0.3 4.8 0.6 0.4 0.0 0.1 2.2 0.0 0.0 0.5 0.0 0.6 2.0 0.0 0.0 0.4 1.0 1.4 0.2 0.0 0.4 0.2 0.1 0.0 0.7 0.2 5.4 0.2 2.8 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.2 0.9 0.0 0.0 0.0 0.8 0.0 0.1 4.4 4.4 4.0 5.3 4.3 4.5 4.6 5.1 4.6 4.3 4.3 4.5 0.8 0.0 0.0 4.6 0.1 0.9 1.9 0.2 1.2 0.0 0.3 0.4 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 503.3 0.4 0.4 0.8 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.3 0.0 2.4 0.4 2.8 0.0 0.0 0.5 0.2 0.0 1.2 0.8 1116.3 8.4 1.3 0.0 0.0 0.1 0.8 0.0 0.5 0.3 0.0 0.0 4.1 0.0 0.7 0.2 0.3 0.2 0.2 0.0 0.5 0.4 8.1 6.0 0.7 0.1 0.0 0.3 0.2 0.2 0.4 ARMCX5 "FLJ12969, GASP5" ENSG00000125962 "Armadillo repeat containing X-linked 5" Q6P1M9 X 102599168-102604159 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 88.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000996 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Nuclear speckles, Cytosol" "Plasma membrane" "HPA000996: AB_1078212" "unprognostic (7.71e-2)" "unprognostic (2.43e-2)" "unprognostic (1.20e-1)" "unprognostic (3.50e-2)" "unprognostic (1.54e-1)" "unprognostic (5.05e-2)" "unprognostic (4.07e-2)" "prognostic favorable (6.58e-5)" "unprognostic (1.12e-1)" "unprognostic (2.76e-2)" "unprognostic (2.83e-1)" "unprognostic (3.28e-3)" "unprognostic (1.17e-1)" "unprognostic (2.40e-1)" "unprognostic (1.17e-2)" "unprognostic (2.83e-1)" "unprognostic (5.24e-2)" 8.2 11.0 10.4 8.8 10.6 10.3 17.8 10.0 11.5 13.7 6.9 12.8 10.8 15.2 15.5 11.0 15.0 10.0 10.7 11.4 9.3 12.6 11.3 11.2 10.4 7.7 7.0 20.3 14.7 19.9 7.2 8.4 7.6 20.6 15.3 10.6 15.7 13.5 9.3 11.2 12.3 13.9 7.3 8.0 13.5 5.4 9.6 16.2 19.5 10.1 13.3 11.2 6.5 11.4 17.8 15.7 36.4 19.4 15.9 17.8 20.4 17.1 13.1 19.5 34.5 18.7 21.5 0.0 20.3 17.2 22.3 15.1 32.8 16.3 22.1 0.0 13.1 17.9 19.2 15.6 20.6 32.7 20.0 22.3 20.7 16.9 20.3 15.5 20.0 0.0 17.6 0.1 26.3 15.8 23.3 3.9 16.4 30.3 29.5 22.7 88.9 0.1 14.5 24.2 17.1 15.4 30.5 15.7 24.7 10.4 10.8 15.4 20.3 14.5 12.8 16.5 12.3 0.0 13.0 0.0 11.4 32.7 37.8 0.1 11.8 3.2 13.9 12.3 13.3 12.5 12.8 10.9 11.3 6.4 17.8 14.0 1.0 9.3 7.8 10.0 9.7 11.1 10.4 10.6 10.0 11.5 11.4 9.3 7.7 7.0 7.6 7.3 9.6 11.4 6.9 6.4 6.9 0.0 9.0 5.6 11.7 8.0 19.4 16.5 8.9 7.7 4.4 7.2 10.3 9.2 20.9 5.7 9.2 6.8 21.5 10.0 0.3 5.9 8.3 9.6 9.6 3.4 0.0 9.7 2.6 9.9 10.7 5.7 1.3 7.8 5.7 9.6 6.0 1.7 0.0 9.8 4.1 7.2 3.5 0.5 8.4 6.6 8.8 0.0 4.6 6.5 10.3 0.0 0.0 9.3 3.8 6.0 12.0 9.3 9.6 10.6 13.7 20.8 0.0 6.7 7.8 3.0 5.3 14.5 5.7 3.7 9.5 7.5 9.7 11.1 ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Collecting duct cells: 12.9;Endometrial ciliated cells: 10.2;Endometrial stromal cells: 7.7;Granulosa cells: 26.0;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.7;AN3-CA: 6.1;fHDF/TERT166: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" 1.2 2.5 2.3 0.6 3.6 0.7 0.8 8.5 3.5 1.8 0.0 0.7 0.5 3.0 1.8 0.8 2.1 1.8 3.1 2.6 2.1 8.3 0.8 0.7 0.4 11.5 5.1 4.3 1.0 3.6 1.3 0.4 12.8 1.6 1.0 1.2 0.7 1.4 0.2 1.0 0.7 2.3 1.0 0.5 1.4 2.2 1.6 0.2 1.5 1.9 0.3 1.2 0.9 0.7 0.0 0.0 9.7 6.1 4.7 1.7 0.0 1.9 1.5 0.3 0.3 0.5 0.1 0.0 0.6 10.8 1.2 0.0 2.9 0.0 0.4 0.1 1.0 0.0 0.0 0.5 0.2 0.0 4.8 1.8 0.0 0.2 0.2 2.7 0.5 0.8 0.1 0.3 1.2 0.3 0.0 0.0 4.5 0.0 2.0 1.4 0.3 2.5 3.9 0.3 1.1 0.0 0.1 0.0 0.3 2.7 0.2 0.2 0.1 1.3 3.5 0.5 2.6 0.3 0.2 0.0 3.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.6 8.5 3.5 2.6 2.1 11.5 5.1 12.8 1.0 1.6 0.7 15.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 12.9 0.0 0.2 0.7 0.0 0.0 2.1 0.0 10.2 7.7 2.3 0.0 0.0 0.0 1.3 0.4 3.0 0.0 2.4 0.0 26.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 44.5 0.0 0.0 ARPC1A "Arc40, SOP2Hs, SOP2L" ENSG00000241685 "Actin related protein 2/3 complex subunit 1A" Q92747 7 99325898-99366262 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 442.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA004334 Approved Approved "Cell Junctions,Cytosol" NA NA 760000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" Cytosol "HPA004334: AB_1078215" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (6.22e-3)" "unprognostic (1.93e-2)" "unprognostic (8.38e-3)" "unprognostic (1.95e-2)" "prognostic unfavorable (4.70e-4)" "unprognostic (2.52e-2)" "unprognostic (2.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.73e-2)" "unprognostic (3.89e-2)" "unprognostic (7.88e-2)" "unprognostic (4.45e-2)" "unprognostic (9.15e-2)" "unprognostic (7.07e-2)" "unprognostic (1.83e-1)" 74.4 82.9 61.6 39.7 63.3 40.4 63.2 60.1 71.9 69.8 71.9 80.7 92.8 60.1 80.9 124.6 75.5 53.3 121.7 78.7 73.9 65.9 77.4 62.2 41.9 64.6 67.7 81.5 63.8 65.4 62.1 54.3 71.7 56.9 78.2 33.0 66.6 55.5 48.0 84.5 84.9 57.2 60.8 52.7 99.1 42.4 68.4 39.2 78.8 47.1 44.9 61.6 74.9 62.9 265.3 144.3 155.1 73.6 144.2 242.4 133.5 185.5 216.1 185.5 184.4 164.4 301.7 92.3 270.5 226.7 273.8 110.6 208.0 270.8 221.5 46.7 186.4 49.7 99.9 137.1 156.1 59.2 63.7 227.6 149.1 237.8 252.0 220.0 310.8 75.9 125.9 105.6 289.8 398.6 99.4 78.5 150.5 295.3 326.1 58.1 107.8 113.9 142.0 162.7 161.7 138.3 180.9 260.2 255.9 264.2 130.2 88.4 239.3 239.0 211.0 424.7 302.1 39.6 80.0 130.7 206.6 130.1 320.2 111.7 49.9 88.8 24.2 80.8 19.3 30.8 23.1 31.5 43.0 28.8 30.0 22.6 63.7 30.7 86.1 31.9 33.5 26.9 61.6 63.3 60.1 71.9 78.7 73.9 64.6 67.7 71.7 60.8 68.4 62.9 124.3 51.3 55.5 20.9 45.2 41.4 139.5 249.1 54.7 38.0 107.2 131.6 46.7 95.8 130.1 58.8 18.8 189.6 27.3 196.2 135.0 213.6 32.1 55.0 43.7 96.4 74.2 68.8 31.6 276.9 345.8 70.6 140.2 57.4 13.3 141.4 135.0 75.8 84.6 33.7 28.0 209.4 132.2 77.5 26.1 24.6 66.8 56.0 80.0 26.2 68.6 79.8 42.2 19.1 28.4 442.5 191.6 67.4 52.4 151.5 295.7 155.5 102.2 40.1 184.1 59.1 188.4 171.6 130.0 88.9 47.9 129.7 29.8 87.7 166.3 280.7 ARPC5 "ARC16, dJ127C7.3, p16-Arc" ENSG00000162704 "Actin related protein 2/3 complex subunit 5" O15511 1 183620846-183635783 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022013, HPA031972" Approved Approved "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA 3300000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane, Cell Junctions, Cytosol" "HPA022013: AB_1845045, HPA031972: " "unprognostic (3.82e-1)" "unprognostic (8.78e-2)" "unprognostic (1.43e-1)" "unprognostic (2.36e-2)" "unprognostic (1.74e-1)" "unprognostic (1.85e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (5.90e-3)" "unprognostic (3.84e-2)" "unprognostic (3.17e-3)" "unprognostic (1.14e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.21e-10)" "unprognostic (3.03e-2)" "unprognostic (4.66e-2)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" 86.1 49.2 17.4 148.2 22.5 69.1 48.8 23.7 23.8 46.5 13.0 104.7 99.5 69.5 15.7 77.8 52.0 52.9 35.7 20.0 22.3 39.0 64.3 103.1 158.9 35.2 22.8 30.6 51.7 29.9 19.7 108.2 29.7 46.0 68.9 8.0 45.9 35.9 18.7 42.6 117.4 78.9 24.0 120.8 88.6 38.4 24.1 130.5 46.0 22.5 131.3 75.9 51.8 37.8 313.4 167.7 141.0 98.1 114.0 161.5 338.7 419.7 317.9 176.3 143.0 150.9 215.9 284.9 463.9 241.7 114.6 211.2 101.1 141.6 93.9 413.6 87.1 172.9 212.6 132.6 185.2 254.8 325.0 197.6 148.2 215.7 170.3 201.2 213.7 196.1 133.3 229.1 233.9 125.6 238.5 67.9 133.7 238.5 63.0 219.2 126.3 278.6 97.3 158.7 61.1 164.7 435.8 186.1 167.3 147.1 185.2 222.5 480.9 259.0 134.5 293.8 410.1 270.1 321.8 196.2 204.5 179.6 204.6 1221.0 987.7 1563.7 395.7 1110.1 315.7 338.3 382.3 407.1 838.9 339.7 409.4 415.4 1852.1 392.6 1267.7 394.3 512.4 1913.3 17.4 22.5 23.7 23.8 20.0 22.3 35.2 22.8 29.7 24.0 24.1 37.8 148.7 375.0 188.9 8.1 163.3 249.1 178.3 275.9 91.0 34.2 79.9 118.9 30.2 150.2 197.6 82.8 14.6 475.1 227.4 283.5 166.3 344.3 35.5 78.8 211.4 186.7 202.0 90.0 21.6 280.2 734.2 166.2 87.1 119.8 258.8 147.7 181.7 87.4 608.5 38.7 13.8 146.6 238.0 556.3 740.8 24.2 125.9 558.5 254.3 20.6 635.1 56.7 423.3 7.5 51.5 381.6 234.5 183.6 132.1 182.6 213.6 152.0 95.2 25.4 243.3 83.9 286.8 151.9 137.3 161.5 244.9 199.5 234.4 144.4 155.4 234.6 ARRB2 "ARR2, BARR2, DKFZp686L0365" ENSG00000141480 "Arrestin beta 2" P32121 17 4710596-4721499 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 263.6;lymphoid tissue: 168.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 262.0;Kupffer cells: 242.5;Langerhans cells: 164.2;Macrophages: 226.4;monocytes: 311.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 195.8;HMC-1: 315.9;NB-4: 199.2;U-937: 279.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075177 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA075177: " "unprognostic (1.12e-1)" "prognostic favorable (2.93e-5)" "unprognostic (1.09e-1)" "unprognostic (1.47e-1)" "unprognostic (7.43e-2)" "unprognostic (3.37e-2)" "unprognostic (2.62e-3)" "unprognostic (3.85e-2)" "unprognostic (3.05e-2)" "unprognostic (2.58e-1)" "unprognostic (1.66e-3)" "prognostic unfavorable (2.61e-5)" "unprognostic (1.32e-2)" "unprognostic (8.61e-2)" "unprognostic (4.92e-2)" "unprognostic (1.49e-1)" "unprognostic (1.88e-1)" 48.6 39.7 54.4 110.0 53.8 263.6 26.1 48.2 62.2 19.3 49.1 29.5 50.5 17.4 10.8 15.1 29.0 31.4 25.0 63.8 67.7 25.2 35.6 94.8 59.4 61.6 58.3 17.5 19.4 16.4 24.9 35.5 59.5 19.5 27.6 16.9 20.9 11.7 12.7 14.6 51.1 29.6 55.4 168.3 35.0 7.2 59.5 45.2 15.8 18.1 38.0 41.6 17.6 66.5 17.3 88.7 34.7 32.9 6.8 9.5 18.6 13.7 18.0 38.4 48.0 31.0 14.2 49.1 12.2 10.3 18.3 28.5 58.0 18.4 39.4 116.6 85.0 195.8 46.8 55.6 10.2 89.2 315.9 8.8 23.5 47.9 18.7 24.9 29.6 89.1 13.5 46.4 8.9 30.5 87.9 199.2 18.9 44.9 18.4 104.3 31.0 53.8 13.2 9.2 36.0 49.2 30.8 50.8 23.6 14.2 24.6 40.0 26.1 14.3 29.1 25.1 51.5 19.8 28.6 27.6 37.9 279.4 21.6 116.2 145.5 269.7 49.1 151.1 35.1 10.1 31.1 51.3 84.9 9.0 29.3 38.7 250.6 29.9 168.6 20.7 28.8 93.5 54.4 53.8 48.2 62.2 63.8 67.7 61.6 58.3 59.5 55.4 59.5 66.5 7.7 22.4 32.3 5.5 26.4 11.5 7.7 16.6 3.4 20.5 9.6 12.3 8.3 14.3 47.9 3.7 2.1 7.5 83.8 7.4 15.6 11.2 0.6 1.5 3.6 10.1 8.4 33.9 20.4 7.3 12.0 8.7 19.4 1.8 94.9 7.8 19.2 12.4 262.0 21.9 18.2 17.0 50.8 242.5 164.2 3.5 5.0 226.4 10.6 42.2 311.3 5.8 89.6 7.1 8.4 6.3 22.0 4.9 23.4 4.4 35.5 17.5 24.4 8.7 19.7 10.9 8.5 1.1 13.1 6.8 8.4 6.0 77.2 3.5 11.4 11.7 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ARVCF ENSG00000099889 "ARVCF delta catenin family member" O00192 22 19969896-20016823 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 22.9;Muller glia cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 20.1;REH: 10.5;SCLC-21H: 18.0;SH-SY5Y: 13.8;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016162, HPA055264, HPA063675" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cell Junctions" "CAB016162: AB_2058690, HPA055264: AB_2682766, HPA063675: AB_2685085" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (4.28e-2)" "unprognostic (3.35e-1)" "unprognostic (3.18e-2)" "unprognostic (4.79e-3)" "unprognostic (1.67e-2)" "unprognostic (2.06e-2)" "unprognostic (1.71e-2)" "unprognostic (2.09e-3)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (9.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.76e-6)" 3.8 3.1 6.4 0.7 5.4 3.2 4.4 18.4 6.2 4.3 1.2 5.9 1.0 4.8 3.2 1.3 3.5 1.3 6.4 5.6 7.1 6.2 6.8 4.5 0.5 7.0 5.2 3.5 5.1 1.7 9.4 1.0 5.7 5.7 0.3 1.4 7.0 1.7 7.4 4.7 2.8 0.7 4.9 10.8 4.8 4.9 8.3 0.2 15.6 1.2 0.1 2.8 2.8 5.1 4.1 0.4 5.5 7.1 0.1 0.0 5.6 1.0 0.4 0.3 0.6 1.1 0.9 1.7 4.5 0.5 0.5 3.8 0.9 1.8 0.0 0.5 6.8 0.5 0.5 4.4 1.6 0.6 1.3 0.1 0.7 0.3 0.2 0.3 4.5 1.3 20.1 0.6 0.1 3.8 0.3 2.6 5.6 1.3 2.3 10.5 0.3 0.5 0.9 0.9 18.0 13.8 1.1 1.7 2.7 0.9 1.5 0.5 1.7 0.1 15.6 0.7 0.3 2.2 0.7 0.5 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.4 18.4 6.2 5.6 7.1 7.0 5.2 5.7 4.9 8.3 5.1 2.3 3.2 2.6 24.2 0.7 2.0 3.0 4.4 0.6 9.7 6.6 7.9 6.0 5.7 3.2 1.8 22.9 5.6 2.3 1.8 0.0 8.9 2.7 2.4 0.9 3.0 9.0 4.0 4.7 5.5 2.2 2.4 1.5 4.5 0.0 4.7 2.5 4.1 1.4 5.0 6.2 7.0 10.2 1.0 1.2 1.7 4.1 0.8 3.6 5.6 0.0 21.7 7.2 8.0 1.8 10.7 0.6 3.4 0.9 4.7 0.8 5.6 4.9 8.6 0.0 7.7 6.2 2.3 8.4 0.4 1.8 4.4 0.6 1.6 2.1 1.5 ASAP1 "CENTB4, DDEF1, KIAA1249, PAP, ZG14P" ENSG00000153317 "ArfGAP with SH3 domain, ankyrin repeat and PH domain 1" Q9ULH1 8 130052104-130443674 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 345.8;Late spermatids: 460.2;Oligodendrocyte precursor cells: 622.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.6" "Group enriched" "Detected in many" 5 "dendritic cells: 3.7;granulocytes: 11.6;monocytes: 6.7" "Cell line enhanced" "Detected in all" "TIME: 167.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011136, CAB037292, HPA048565" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA 31000 "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome, Cytosol" "CAB037292: AB_476723, HPA011136: AB_2668438, HPA048565: AB_2680445" "unprognostic (1.20e-2)" "unprognostic (1.15e-2)" "unprognostic (7.68e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.77e-1)" "unprognostic (3.33e-2)" "prognostic unfavorable (5.63e-8)" "prognostic unfavorable (3.56e-5)" "unprognostic (3.34e-1)" "unprognostic (5.27e-2)" "unprognostic (8.56e-3)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.50e-7)" "unprognostic (3.79e-2)" "unprognostic (1.19e-1)" "unprognostic (7.38e-2)" "unprognostic (1.22e-3)" 35.1 22.2 13.5 12.2 15.1 47.8 24.0 7.6 22.0 17.6 3.9 13.4 5.5 19.0 12.2 10.7 17.2 14.6 24.7 14.7 10.5 11.9 9.3 30.1 18.0 14.2 20.9 18.2 7.8 18.1 10.5 27.8 16.5 12.7 8.9 8.6 8.5 11.4 13.4 17.3 12.2 17.9 9.4 30.0 10.6 28.5 29.1 16.3 16.4 10.4 19.0 15.9 15.6 17.1 48.9 31.5 41.1 27.4 46.7 61.9 37.1 44.2 83.8 57.2 62.3 17.5 18.2 14.4 31.8 67.7 38.6 13.2 24.7 41.4 86.3 20.6 15.9 22.6 20.7 23.6 119.9 10.4 6.7 61.7 15.3 33.6 50.3 66.9 60.2 7.7 13.0 45.7 54.0 15.1 13.3 9.8 13.1 24.1 30.5 13.6 9.6 7.0 18.1 25.2 14.6 44.4 32.4 20.5 26.5 42.5 17.0 22.4 167.5 45.9 28.9 20.6 69.8 42.2 12.0 9.7 34.6 14.6 50.3 0.0 2.2 1.5 0.5 2.1 0.3 1.3 1.0 0.9 3.7 1.0 1.3 0.8 11.6 0.6 6.7 0.4 0.8 1.1 13.5 15.1 7.6 22.0 14.7 10.5 14.2 20.9 16.5 9.4 29.1 17.1 97.2 3.2 6.3 206.6 22.7 47.7 21.9 12.0 29.6 25.0 12.4 14.7 33.7 27.1 11.5 3.7 16.7 42.2 14.6 3.6 3.9 10.5 159.7 14.3 34.2 109.1 13.1 98.9 345.8 8.7 37.6 43.7 4.6 27.7 9.5 30.1 103.9 8.2 64.0 62.2 225.8 4.3 8.2 56.1 168.8 460.2 39.1 73.1 44.4 181.8 71.4 9.5 15.5 622.3 245.9 12.5 4.7 54.9 13.7 37.9 5.8 4.3 4.2 7.8 78.9 28.5 90.1 61.4 95.5 25.2 44.9 46.7 23.1 58.9 4.8 22.0 ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 217.2;tongue: 67.0" "Cell type enhanced" "Detected in some" "Early spermatids: 52.7;Late spermatids: 293.6;Skeletal myocytes: 79.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;prostate cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 1184.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028870: AB_10611679" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.90e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" "unprognostic (6.80e-3)" 0.1 0.0 0.4 0.9 0.5 0.0 0.0 1.3 1.0 1.0 0.2 11.1 0.3 0.6 0.1 10.5 0.1 1.2 3.9 0.5 0.4 0.7 0.0 0.2 0.0 0.9 1.5 0.0 0.0 0.1 0.4 0.0 0.8 12.9 3.3 0.0 23.9 0.3 217.2 0.2 1.2 2.5 0.8 0.0 4.7 7.3 0.5 0.1 0.0 67.0 0.0 19.2 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 29.1 0.0 25.9 54.7 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1184.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.3 1.0 0.5 0.4 0.9 1.5 0.8 0.8 0.5 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.7 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 293.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.8 0.0 0.0 1.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 79.6 0.6 0.9 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 ASGR1 CLEC4H1 ENSG00000141505 "Asialoglycoprotein receptor 1" P07306 17 7173431-7179564 "Predicted intracellular proteins, Predicted secreted proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 41 "liver: 1092.3" "Cell type enriched" "Detected in many" 4 "Hepatocytes: 1107.9" "Cancer enriched" "Detected in many" 90 "liver cancer: 131.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 115.2;intermediate monocyte: 55.5;myeloid DC: 41.2" "Group enriched" "Detected in many" 8 "dendritic cells: 41.2;monocytes: 115.2" "Cell line enriched" "Detected in some" 29 "Hep G2: 493.2" "Region enriched" "Detected in all" 9 "cerebellum: 44.1" "Not detected" "Not detected" "HPA011954, HPA012852" Enhanced Supported "Vesicles,Cell Junctions" "Secreted to blood" NA NA 10000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Cell Junctions" "HPA011954: AB_1845079, HPA012852: AB_1845080" "unprognostic (3.56e-3)" "unprognostic (3.57e-1)" "unprognostic (8.76e-2)" "unprognostic (4.05e-2)" "unprognostic (1.88e-1)" "unprognostic (1.22e-1)" "unprognostic (1.86e-2)" "unprognostic (5.37e-2)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (8.55e-5)" "unprognostic (1.55e-1)" "unprognostic (8.33e-11)" "unprognostic (1.45e-1)" "unprognostic (2.00e-1)" "unprognostic (1.73e-3)" "unprognostic (4.46e-3)" 2.6 1.5 7.7 3.7 7.8 2.5 1.8 17.0 10.9 1.6 7.0 1.2 2.2 1.3 0.6 1.7 1.8 2.9 1.1 7.9 7.6 1.4 1092.3 3.9 1.3 8.0 8.2 1.1 0.9 7.0 2.9 0.5 8.3 1.7 0.5 4.8 0.9 0.3 1.5 4.4 1.4 1.3 6.0 4.8 1.4 26.5 7.8 0.4 5.8 0.4 0.3 1.7 1.5 8.7 0.3 0.7 9.2 4.2 0.0 0.2 0.8 0.8 0.9 0.9 1.6 16.8 0.5 0.3 1.1 0.2 0.4 0.2 0.3 0.2 0.4 0.3 0.8 1.2 1.4 493.2 0.1 0.8 1.7 1.2 0.2 0.5 0.1 0.6 8.4 7.4 1.1 0.6 0.5 0.4 0.7 1.2 1.7 0.2 0.4 0.9 3.5 0.2 0.1 0.7 0.6 3.5 0.7 0.3 0.6 1.5 0.5 0.2 1.2 0.9 3.4 0.7 0.4 0.2 0.3 0.5 0.6 0.4 0.3 10.0 115.2 0.4 0.2 55.5 1.1 0.5 0.2 0.2 41.2 0.5 0.3 0.4 3.3 0.5 14.9 1.8 0.3 36.7 7.7 7.8 17.0 10.9 7.9 7.6 8.0 8.2 8.3 6.0 7.8 8.7 6.0 0.0 4.7 2.9 2.6 3.2 1.7 2.0 3.4 37.8 5.6 6.0 1.5 55.8 2.0 3.7 160.6 3.6 2.9 1.4 3.9 0.9 235.4 4.2 3.6 13.2 15.6 16.8 4.6 0.2 3.7 1.9 3.6 16.5 0.0 5.1 27.5 1107.9 39.9 15.2 4.8 2.3 2.0 97.4 11.9 115.8 2.5 52.6 0.0 1.9 77.2 3.6 0.0 2.0 0.6 0.3 1.3 1.2 0.0 0.9 0.2 6.8 1.6 42.3 0.0 0.8 1.9 6.5 9.7 9.9 4.8 12.4 1.4 1.6 1.3 2.4 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042289: AB_10795608" "unprognostic (9.39e-2)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (5.40e-3)" "unprognostic (2.87e-1)" "unprognostic (2.66e-2)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (9.73e-3)" "prognostic favorable (4.25e-4)" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.54e-1)" 28.9 18.9 19.7 17.9 20.3 31.6 21.4 19.2 21.5 19.9 14.7 22.5 18.2 22.0 17.1 23.8 20.1 17.4 21.3 20.2 17.4 23.3 23.6 18.5 27.9 16.7 16.1 26.2 17.7 24.8 12.0 22.1 16.7 19.9 22.3 21.7 20.6 21.0 32.4 20.4 18.3 24.2 16.5 18.9 22.1 41.3 19.0 33.6 21.1 27.7 28.3 18.5 16.1 18.1 45.6 23.3 39.8 39.8 26.3 34.0 49.8 44.1 45.7 53.5 47.0 24.9 21.1 51.4 38.2 37.1 27.2 27.5 49.0 24.8 50.4 20.3 22.4 200.3 22.9 51.7 39.4 32.0 41.3 28.6 22.9 25.0 27.7 28.1 43.9 48.0 138.2 40.0 53.7 26.1 91.9 40.7 51.7 39.3 15.6 38.2 42.9 23.4 28.9 33.1 18.3 32.4 33.5 22.5 38.4 37.1 27.4 40.4 33.5 35.3 35.0 50.4 37.6 37.8 48.7 44.9 35.2 44.7 49.7 39.9 23.0 55.9 16.8 26.8 18.1 19.6 18.8 20.0 27.7 19.2 19.3 18.4 19.2 26.1 25.8 15.8 21.3 21.6 19.7 20.3 19.2 21.5 20.2 17.4 16.7 16.1 16.7 16.5 19.0 18.1 11.1 12.8 15.8 18.3 14.3 6.9 9.3 13.3 10.8 12.9 9.6 8.0 18.1 8.6 15.9 12.9 10.4 37.0 15.9 11.5 7.9 21.2 10.8 12.7 13.2 14.0 10.8 62.1 19.7 28.7 37.2 17.3 8.6 10.8 19.6 38.2 12.8 11.9 24.2 6.7 21.4 11.6 12.2 17.2 5.7 13.0 23.3 17.0 23.2 15.9 29.2 17.8 19.6 17.6 16.5 21.3 8.9 20.7 8.4 6.2 12.8 17.1 18.0 15.5 13.1 14.6 20.7 69.6 33.9 11.6 6.8 30.9 11.9 37.3 10.9 7.4 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ASPSCR1 "ASPL, ASPS, TUG, UBXD9, UBXN9" ENSG00000169696 "ASPSCR1 tether for SLC2A4, UBX domain containing" Q9BZE9 17 81976807-82017406 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 222.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "Hep G2: 298.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026749 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA026749: AB_1845114" "unprognostic (5.01e-2)" "unprognostic (1.19e-3)" "unprognostic (7.61e-2)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "prognostic favorable (8.55e-4)" "unprognostic (2.02e-1)" "unprognostic (2.07e-2)" "unprognostic (3.43e-1)" "unprognostic (1.71e-3)" "prognostic favorable (2.67e-4)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.26e-4)" "unprognostic (3.16e-2)" "unprognostic (1.13e-1)" "unprognostic (2.27e-1)" "unprognostic (1.01e-2)" 16.5 20.4 16.6 8.4 17.0 15.0 16.9 16.5 20.4 16.2 17.7 16.0 13.6 15.6 7.9 16.8 14.0 7.7 26.1 16.2 15.5 27.3 57.9 17.3 12.2 20.1 16.6 13.4 22.8 14.8 30.6 12.9 18.3 21.6 4.6 5.7 18.3 6.7 44.3 20.5 18.1 5.2 14.7 20.7 22.7 30.0 17.2 8.3 25.9 5.8 6.4 16.0 14.2 21.5 19.3 33.3 13.0 17.9 7.5 9.3 55.4 17.7 12.6 19.3 19.5 20.3 21.3 19.2 18.1 12.4 16.3 9.8 12.0 13.1 6.2 12.9 41.0 21.4 28.7 298.1 25.5 19.1 29.9 10.9 13.9 9.5 6.6 10.0 19.5 16.0 22.0 25.0 11.6 65.0 16.9 41.8 15.5 32.8 23.5 19.2 18.7 39.4 18.0 17.0 32.4 34.8 14.6 42.2 35.2 12.3 27.2 41.4 16.6 35.7 24.5 26.4 22.8 20.2 12.5 21.6 19.2 19.3 21.3 24.0 11.7 8.6 6.6 8.0 3.7 9.0 10.0 8.8 14.7 9.0 7.7 5.8 2.7 8.0 10.4 9.3 5.3 5.6 16.6 17.0 16.5 20.4 16.2 15.5 20.1 16.6 18.3 14.7 17.2 21.5 13.9 9.6 44.7 19.9 24.1 13.4 23.7 24.4 23.3 23.3 19.6 15.6 13.6 27.1 19.8 14.7 41.7 73.7 25.8 29.3 39.2 24.2 49.1 16.2 14.9 16.1 25.0 17.9 12.4 26.2 222.6 17.5 46.9 20.1 21.5 31.0 12.8 56.1 44.7 50.5 12.1 31.5 20.3 26.7 18.6 96.0 11.8 21.7 19.6 1.9 23.8 57.8 19.6 10.6 14.1 17.6 25.8 17.7 27.3 24.9 42.5 58.3 18.5 39.4 13.1 14.7 37.4 41.7 51.0 20.3 14.3 59.4 18.4 23.6 33.3 23.1 ATG13 KIAA0652 ENSG00000175224 "Autophagy related 13" O75143 11 46617527-46674818 "Cancer-related genes, Predicted intracellular proteins, Transporters" Autophagy "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039350 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA039350: AB_10673142" "unprognostic (3.66e-1)" "unprognostic (1.14e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-1)" "unprognostic (5.36e-2)" "unprognostic (2.31e-1)" "prognostic unfavorable (8.59e-5)" "unprognostic (1.05e-1)" "unprognostic (1.10e-1)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (7.57e-2)" "unprognostic (2.44e-2)" "unprognostic (2.41e-1)" "unprognostic (2.14e-1)" "unprognostic (7.68e-2)" "unprognostic (3.47e-1)" 32.3 39.7 55.9 26.1 67.6 60.5 30.1 49.4 63.7 30.6 46.1 26.5 29.3 28.2 32.2 32.0 32.1 29.6 36.8 55.2 51.8 28.7 43.9 25.3 31.5 60.2 59.4 29.7 44.6 37.5 57.7 21.9 61.8 31.1 24.1 48.4 35.9 25.5 34.5 39.6 28.0 24.8 51.8 36.4 36.4 82.0 59.6 40.6 36.8 33.4 33.6 27.4 29.1 87.9 32.8 58.5 44.1 26.1 60.2 70.0 44.5 37.5 65.4 45.0 57.0 40.2 31.7 30.2 25.6 56.5 58.1 38.8 42.7 50.3 45.2 57.9 81.1 32.8 39.7 71.2 67.4 44.1 54.1 84.9 59.0 31.0 67.9 63.9 45.0 69.4 57.8 66.8 40.8 48.8 44.0 65.1 55.0 59.5 49.9 41.4 57.0 53.7 29.9 34.5 41.6 42.1 51.2 40.6 55.4 42.1 58.0 89.5 44.6 54.7 33.3 51.1 41.2 61.1 73.8 38.6 67.8 39.3 40.9 41.7 36.1 48.5 35.1 42.6 27.9 27.1 31.2 27.8 35.0 21.7 26.4 29.2 67.7 31.5 35.1 25.6 44.7 39.9 55.9 67.6 49.4 63.7 55.2 51.8 60.2 59.4 61.8 51.8 59.6 87.9 10.6 16.0 16.2 14.7 16.9 9.3 12.0 9.0 13.1 22.7 16.7 12.3 13.2 8.6 12.0 12.9 39.6 9.9 25.4 24.5 7.9 18.9 42.7 30.0 17.3 12.7 18.0 28.2 23.4 32.3 22.4 14.8 20.9 46.1 8.8 22.5 13.2 22.5 15.1 33.7 25.7 22.6 14.2 19.1 9.8 46.8 11.5 15.7 12.4 15.0 22.8 16.3 19.6 25.1 61.0 30.4 12.9 11.3 36.6 19.9 19.5 13.5 9.4 32.2 13.1 16.9 19.9 46.3 16.3 15.8 11.5 26.4 18.0 9.8 11.9 24.3 ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 657.9;Spermatocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" 33.1 38.7 41.4 49.1 50.1 94.1 34.7 51.3 53.5 28.3 38.2 38.2 38.2 24.7 24.7 34.8 23.2 24.7 33.3 39.7 46.8 41.6 43.3 31.1 48.4 49.1 48.2 25.6 41.8 44.8 30.6 33.6 48.5 23.2 40.3 29.1 29.4 28.3 29.5 29.8 36.6 29.9 48.2 48.2 37.7 85.3 45.6 51.2 42.2 33.6 46.3 38.7 26.3 55.7 105.0 55.9 51.5 52.6 66.6 54.5 57.5 89.8 65.3 86.9 78.9 78.9 60.6 130.3 66.6 78.0 106.6 74.1 84.9 78.0 120.9 22.8 40.9 82.0 52.3 51.0 102.9 145.2 67.0 50.6 58.3 85.5 130.2 56.8 82.2 81.2 71.6 108.8 92.9 91.4 86.4 68.2 56.3 135.8 109.7 74.9 45.9 110.5 72.6 56.1 88.1 34.7 74.7 70.5 109.5 48.4 79.8 107.5 66.7 92.3 75.8 39.4 80.1 70.2 72.0 201.3 84.4 133.2 69.4 64.4 167.7 121.9 39.4 258.8 49.4 61.8 48.0 49.2 169.4 59.2 46.2 46.3 174.2 50.5 327.9 36.3 75.6 138.2 41.4 50.1 51.3 53.5 39.7 46.8 49.1 48.2 48.5 48.2 45.6 55.7 45.6 48.1 39.0 10.1 53.3 74.1 42.4 74.3 37.5 22.5 32.0 50.2 86.2 37.1 51.3 25.8 12.5 73.1 45.3 47.0 117.4 73.7 657.9 37.9 40.8 54.1 31.2 90.0 11.7 86.1 85.0 42.6 36.7 45.2 39.9 42.0 40.0 40.0 121.3 18.5 11.4 53.3 75.3 106.3 131.1 146.5 42.6 134.8 69.4 11.2 185.8 42.1 54.6 13.0 33.7 70.9 49.2 43.2 70.4 39.1 76.0 87.5 37.3 22.2 59.2 45.5 77.6 341.0 119.7 57.4 70.6 122.3 55.0 68.6 69.8 54.2 ATG7 "APG7L, DKFZp434N0735, GSA7" ENSG00000197548 "Autophagy related 7" O95352 3 11272309-11557665 "Predicted intracellular proteins, Transporters" "Autophagy, Biological rhythms, Protein transport, Transport, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 160.0;Excitatory neurons: 178.7;Inhibitory neurons: 176.4;Late spermatids: 119.1;Microglial cells: 132.1;Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 60.1;classical monocyte: 136.6;eosinophil: 88.4;intermediate monocyte: 79.4;myeloid DC: 82.4;neutrophil: 107.4;non-classical monocyte: 60.8" "Group enriched" "Detected in all" 5 "dendritic cells: 82.4;granulocytes: 107.4;monocytes: 136.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007639, CAB018771" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 33000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane" "CAB018771: AB_2062165, HPA007639: AB_1845162" "unprognostic (3.97e-2)" "unprognostic (2.83e-2)" "prognostic favorable (9.66e-4)" "unprognostic (1.18e-2)" "unprognostic (2.79e-1)" "unprognostic (5.19e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (1.82e-1)" "unprognostic (2.40e-1)" "unprognostic (1.80e-3)" "unprognostic (2.30e-2)" "unprognostic (2.67e-1)" "prognostic favorable (9.55e-4)" "unprognostic (1.61e-1)" "unprognostic (3.65e-2)" "unprognostic (1.16e-1)" "unprognostic (1.50e-1)" 16.8 13.5 11.2 25.0 13.1 47.6 18.0 7.3 21.8 14.5 17.0 17.3 13.0 14.9 16.7 16.7 18.7 16.6 10.8 12.4 9.5 13.7 13.2 20.9 23.9 15.0 15.0 12.2 10.9 21.2 7.5 21.0 13.1 11.6 19.2 10.3 12.2 11.9 13.0 18.0 13.8 20.0 12.4 16.4 14.4 22.5 15.4 13.1 13.0 13.5 25.0 20.3 12.0 21.3 48.5 37.1 16.7 9.2 28.0 36.7 80.4 44.5 56.8 43.1 49.9 16.0 42.5 22.1 26.5 39.2 45.1 14.5 18.3 62.0 73.8 19.8 23.5 16.0 33.6 19.6 36.9 46.8 50.8 38.0 28.2 83.6 52.0 45.4 60.5 14.0 24.1 17.9 60.6 31.3 13.7 21.3 13.0 22.2 47.9 17.1 19.6 19.9 32.5 34.2 14.6 14.5 31.6 26.4 17.5 20.1 28.8 44.7 42.5 36.0 25.7 23.6 63.2 11.1 31.8 38.1 57.8 43.1 49.9 60.1 136.6 88.4 15.9 79.4 12.3 13.0 12.9 15.1 82.4 12.3 11.7 13.7 107.4 21.3 60.8 14.7 12.4 56.8 11.2 13.1 7.3 21.8 12.4 9.5 15.0 15.0 13.1 12.4 15.4 21.3 6.4 0.0 9.8 160.0 11.4 11.1 7.3 21.6 9.6 18.1 7.4 3.6 4.2 4.3 12.5 7.3 18.8 16.5 7.9 8.3 7.9 12.3 44.2 10.6 9.5 14.6 11.4 9.5 178.7 12.9 16.8 11.0 10.7 13.2 14.7 12.4 19.6 9.0 57.6 20.2 176.4 7.6 22.4 25.8 12.1 119.1 10.2 28.8 3.6 132.1 30.6 8.1 13.4 99.0 137.2 17.4 7.3 9.8 10.8 6.4 8.4 6.8 16.5 12.5 6.6 11.7 10.6 22.4 11.9 9.8 7.7 19.2 10.1 9.9 7.6 7.4 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 932.7;Proximal tubular cells: 1449.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (5.55e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (3.34e-2)" "unprognostic (2.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.72e-1)" "unprognostic (7.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-1)" 102.0 136.9 173.3 65.9 183.6 73.8 100.1 180.8 201.1 84.4 181.9 84.7 81.8 73.7 98.0 112.1 64.6 63.6 107.4 170.0 189.7 217.1 260.9 80.3 142.9 181.9 184.7 57.8 57.1 180.6 81.2 69.8 183.6 100.2 64.3 24.9 93.0 74.6 53.6 102.8 83.0 75.9 184.9 124.4 76.1 72.9 185.6 82.6 119.3 39.5 128.2 91.7 84.2 192.8 112.0 181.9 104.4 73.1 275.1 224.2 136.6 197.7 225.8 197.2 267.3 248.2 235.8 224.9 233.3 345.7 437.1 102.4 129.2 502.5 161.3 143.9 220.3 98.7 118.4 255.1 254.1 137.5 108.5 291.3 105.0 246.0 161.1 144.7 295.3 138.5 83.4 642.7 305.1 276.6 102.3 304.0 59.8 249.8 382.3 61.4 120.0 350.0 190.6 98.1 136.2 80.0 169.3 476.6 763.4 117.2 234.2 165.3 328.5 201.0 159.4 246.9 345.9 522.6 513.4 136.2 271.7 92.3 846.1 154.6 207.9 199.4 75.1 247.6 69.0 98.6 67.3 66.2 171.3 68.3 53.0 58.0 155.3 97.0 177.2 217.8 103.5 117.3 173.3 183.6 180.8 201.1 170.0 189.7 181.9 184.7 183.6 184.9 185.6 192.8 209.1 57.7 56.6 8.1 93.2 67.7 79.8 204.5 70.0 22.7 250.1 246.5 112.1 165.8 102.2 211.5 14.6 146.0 65.6 213.6 541.9 207.6 178.9 121.1 171.1 183.2 150.7 104.1 6.4 159.1 218.7 127.3 96.8 135.3 73.0 117.8 236.7 932.7 671.2 25.2 9.1 171.1 164.8 221.4 166.0 321.1 83.0 230.4 238.3 4.7 436.7 185.7 88.6 5.5 22.7 318.1 238.7 103.4 170.4 124.2 727.0 1449.1 108.5 24.9 92.1 69.0 235.2 81.9 156.0 153.1 106.4 118.8 55.4 96.6 152.7 122.2 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP12A "ATP1AL1, H-K-ATPase, HK" ENSG00000075673 "ATPase H+/K+ transporting non-gastric alpha2 subunit" P54707 13 24680408-24712472 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Potassium transport, Sodium transport, Transport" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "esophagus: 11.2;kidney: 5.4;lymphoid tissue: 14.8;placenta: 5.6;skin 1: 6.2" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 75.6;Club cells: 49.2" "Cancer enhanced" "Detected in many" "testis cancer: 12.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "SuSa: 4.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA039526 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Actin filaments" Cytosol "HPA039526: AB_10673534" "unprognostic (8.33e-3)" "unprognostic (3.58e-2)" "unprognostic (2.93e-1)" "unprognostic (5.21e-3)" "unprognostic (2.58e-1)" "unprognostic (1.21e-2)" "unprognostic (8.03e-3)" "unprognostic (2.64e-1)" "unprognostic (1.50e-1)" "unprognostic (1.18e-1)" "unprognostic (3.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.67e-1)" "unprognostic (6.80e-2)" "unprognostic (8.22e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 11.2 0.0 0.0 0.0 0.1 0.0 5.4 0.0 0.6 0.0 0.0 0.1 0.0 0.1 0.6 0.0 5.6 0.0 0.2 2.0 0.0 0.1 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 14.8 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 1.7 1.0 0.0 0.0 0.0 75.6 0.0 0.0 0.2 0.3 0.4 0.0 49.2 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 2.2 1.3 0.0 0.0 0.0 0.0 0.0 0.7 0.2 8.2 0.0 0.0 0.1 0.3 0.1 0.0 1.0 0.0 0.0 0.0 1.0 0.6 0.1 1.2 0.0 0.0 0.2 0.0 0.1 13.6 0.0 0.0 0.0 1.8 1.0 1.1 0.0 0.0 0.0 0.1 0.0 0.1 1.3 ATP13A3 AFURS1 ENSG00000133657 "ATPase 13A3" Q9H7F0 3 194402672-194498364 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 384.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029471 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" Nucleoli "Plasma membrane, Cytosol" "HPA029471: AB_10600784" "unprognostic (5.07e-2)" "unprognostic (3.53e-2)" "unprognostic (2.94e-1)" "unprognostic (5.31e-2)" "unprognostic (3.20e-2)" "unprognostic (3.55e-1)" "unprognostic (1.57e-1)" "unprognostic (9.87e-2)" "unprognostic (1.32e-1)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.60e-4)" "unprognostic (2.70e-2)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.22e-1)" "unprognostic (1.65e-1)" "unprognostic (1.34e-2)" "unprognostic (3.77e-1)" 38.0 22.5 8.5 32.0 9.3 36.9 22.8 12.2 14.8 17.0 18.4 21.2 20.2 18.9 17.0 18.0 17.4 24.2 55.7 10.4 9.3 36.2 87.0 35.5 20.8 9.7 8.4 15.9 16.4 50.3 15.3 54.8 9.1 15.5 22.0 11.6 21.8 15.2 17.0 11.5 16.6 16.9 9.5 16.9 24.4 9.6 12.8 16.3 46.0 14.4 19.4 40.1 16.3 10.1 184.6 19.3 33.0 35.2 49.7 64.9 96.8 62.7 75.4 74.9 132.5 114.1 45.2 74.2 161.1 89.4 197.9 64.2 37.5 66.9 171.4 175.5 31.4 43.1 24.8 31.7 77.1 139.7 91.6 32.6 36.8 127.8 89.0 105.0 38.0 34.9 46.2 139.1 90.7 41.0 53.9 34.8 41.1 64.5 33.5 40.0 77.1 48.8 71.6 53.4 52.4 30.5 64.1 77.9 52.9 31.2 127.7 92.4 37.1 81.2 64.2 162.1 116.5 93.4 141.2 116.6 149.3 80.6 55.7 0.2 0.4 0.4 0.4 0.6 0.5 0.4 0.4 0.7 0.6 0.2 0.5 0.5 0.0 0.6 0.2 0.3 1.0 0.2 8.5 9.3 12.2 14.8 10.4 9.3 9.7 8.4 9.1 9.5 12.8 10.1 56.6 51.3 34.1 51.6 22.3 82.5 49.1 42.1 21.1 25.9 32.1 16.6 50.0 78.6 35.9 49.7 20.9 29.6 26.6 43.7 3.9 66.6 2.0 52.3 65.4 50.5 30.6 23.5 61.8 71.4 19.0 53.2 42.8 181.8 8.8 27.9 68.9 153.2 37.2 15.2 80.6 24.1 26.4 31.1 384.4 2.3 10.2 110.1 62.2 76.8 27.0 8.4 18.6 64.3 49.6 87.8 23.7 13.2 37.8 94.3 11.6 41.4 31.7 13.6 13.1 35.8 42.4 15.2 6.8 36.5 71.2 64.6 24.4 14.1 24.7 69.9 ATP13A5 FLJ16025 ENSG00000187527 "ATPase 13A5" Q4VNC0 3 193274789-193378820 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 17.3;choroid plexus: 38.5;salivary gland: 11.7" "Group enriched" "Detected in some" 5 "Astrocytes: 37.9;Oligodendrocyte precursor cells: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA031771, HPA031772, HPA031774" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA031771: AB_2674038, HPA031772: , HPA031774: AB_2674039" "unprognostic (7.98e-2)" "unprognostic (3.01e-4)" "unprognostic (2.06e-3)" "unprognostic (2.72e-3)" "unprognostic (3.93e-1)" "unprognostic (1.67e-4)" "unprognostic (3.03e-1)" "unprognostic (2.31e-1)" "unprognostic (2.14e-2)" "unprognostic (1.73e-1)" "unprognostic (7.15e-2)" "unprognostic (1.10e-1)" "unprognostic (8.10e-2)" 0.0 0.1 2.3 0.0 1.9 0.2 17.3 1.5 2.7 0.0 38.5 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.2 3.1 1.8 0.2 0.0 0.5 0.1 1.6 2.3 0.2 0.1 0.2 0.3 0.0 1.5 0.0 0.0 0.8 11.7 0.0 1.3 3.9 0.0 0.0 0.8 0.0 1.6 0.4 2.4 0.0 1.3 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 2.3 1.9 1.5 2.7 3.1 1.8 1.6 2.3 1.5 0.8 2.4 1.8 0.1 0.0 0.5 37.9 0.0 0.0 0.0 0.3 0.0 0.0 5.8 5.8 0.7 0.0 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.4 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.9 0.0 0.0 0.0 26.2 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 982.6;Late spermatids: 930.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB020697: , HPA048963: AB_2680574" "unprognostic (2.31e-1)" "unprognostic (1.11e-3)" "unprognostic (2.75e-1)" "prognostic favorable (5.19e-5)" "unprognostic (2.60e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (8.11e-3)" "unprognostic (6.99e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.29e-5)" "unprognostic (5.14e-2)" "unprognostic (2.04e-1)" "unprognostic (7.19e-3)" "unprognostic (6.15e-2)" 229.4 349.6 62.2 81.0 62.8 63.0 87.0 78.5 78.8 98.4 100.5 146.7 112.7 75.7 37.6 182.3 96.2 55.4 102.8 63.6 74.7 128.4 24.5 191.0 41.3 71.1 66.6 180.0 36.7 20.3 168.7 96.7 76.5 102.0 168.0 43.6 85.8 46.2 26.7 259.3 125.0 71.4 68.7 65.7 66.3 75.8 70.6 51.4 75.8 16.0 57.1 101.0 161.2 62.2 280.8 170.1 155.5 145.6 411.7 118.0 354.7 322.2 287.6 224.2 252.1 253.7 136.5 223.3 278.2 243.5 328.4 595.8 157.0 152.2 253.4 120.4 190.0 195.7 161.4 156.8 161.7 164.9 149.1 126.5 355.1 179.1 169.7 162.4 245.7 156.3 135.9 193.7 233.8 114.6 165.6 275.0 213.6 384.5 76.1 225.0 116.4 227.1 191.1 186.7 127.6 86.0 413.2 188.5 455.9 270.7 145.6 197.2 170.7 196.4 76.3 298.8 189.8 138.0 197.6 367.5 259.5 176.5 165.2 69.7 104.1 35.4 70.4 174.3 51.7 39.7 56.3 74.8 103.3 30.4 32.6 59.6 6.7 32.0 260.4 64.8 68.4 103.7 62.2 62.8 78.5 78.8 63.6 74.7 71.1 66.6 76.5 68.7 70.6 62.2 114.7 57.7 41.9 38.2 143.4 492.8 428.3 535.9 326.7 35.9 53.0 46.4 19.7 17.2 177.6 220.7 25.0 281.3 464.5 982.6 41.1 73.9 465.9 86.0 72.2 199.2 56.1 147.1 107.5 60.6 226.8 164.1 24.5 127.2 130.7 94.3 100.6 9.0 305.9 25.2 91.2 65.2 164.8 148.0 678.3 930.5 84.8 455.3 222.3 37.5 364.8 46.3 75.2 46.3 54.7 70.6 321.1 68.4 153.1 396.5 413.3 41.5 33.3 28.4 124.9 99.5 265.2 69.0 200.2 178.4 414.4 391.4 216.1 122.2 134.9 370.2 ATP23 "KUB3, XRCC6BP1" ENSG00000166896 "ATP23 metallopeptidase and ATP synthase assembly factor homolog" Q9Y6H3 12 57906039-57959148 "Enzymes, Predicted intracellular proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 27.8" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 12.7;Cytotrophoblasts: 14.4;Distal tubular cells: 17.6;Extravillous trophoblasts: 15.2;Proximal tubular cells: 26.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.6" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.6" "Cell line enhanced" "Detected in some" "A549: 1.0;Karpas-707: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035804, HPA043204" Uncertain Enhanced "Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "Cell Junctions, Cytosol" "HPA035804: AB_10601026, HPA043204: AB_2678361" "unprognostic (2.56e-1)" "unprognostic (1.31e-2)" "unprognostic (8.82e-2)" "unprognostic (2.92e-2)" "unprognostic (2.30e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (5.28e-2)" "unprognostic (5.41e-3)" "unprognostic (1.03e-2)" "unprognostic (1.24e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.44e-5)" "unprognostic (4.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-1)" 7.5 4.9 0.6 0.4 0.5 0.1 5.6 0.6 0.9 4.1 0.5 8.1 0.2 3.1 0.0 5.6 3.2 0.0 4.6 1.0 0.3 4.0 5.2 2.6 0.1 0.4 0.2 3.1 5.9 0.0 2.8 0.1 0.4 3.3 0.0 0.5 3.6 0.0 12.4 4.4 4.3 0.0 0.3 3.2 4.2 27.8 0.5 0.0 3.5 0.0 0.1 4.7 4.0 0.3 0.6 1.0 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.9 0.2 0.0 0.0 0.4 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.6 2.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.6 0.8 0.1 0.0 0.4 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.4 0.3 0.0 0.4 0.0 0.0 0.4 0.0 0.6 0.1 0.2 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.0 0.3 0.2 0.2 1.6 0.1 0.1 0.1 0.1 0.0 0.6 0.5 0.6 0.9 1.0 0.3 0.4 0.2 0.4 0.3 0.5 0.3 8.0 0.0 9.2 0.0 2.3 0.0 0.0 0.0 0.0 0.0 7.4 12.7 0.0 0.0 1.8 3.7 0.0 14.4 4.2 0.0 17.6 6.1 0.0 5.6 4.9 2.8 0.0 0.0 0.0 10.7 15.2 2.3 0.0 6.0 11.4 6.8 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.9 0.0 0.0 26.1 0.7 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 3.0 9.5 0.0 0.0 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 781.6;Langerhans cells: 435.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 314.6;LHCN-M2: 501.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 18.5 11.2 33.0 25.6 92.0 106.8 19.6 14.0 59.1 18.8 0.0 33.1 40.8 18.2 12.1 14.7 18.6 25.2 11.0 52.7 4.9 16.4 22.7 21.3 29.2 0.0 14.4 13.1 17.1 21.5 11.0 27.3 0.0 13.9 32.3 71.2 11.5 14.9 24.4 26.0 30.1 19.7 0.0 30.7 29.0 23.0 10.9 18.4 14.4 24.1 28.8 37.0 10.6 34.9 24.0 117.8 45.5 22.1 64.5 102.2 20.9 71.2 232.6 67.5 106.8 47.7 21.6 46.8 4.9 99.3 77.6 21.0 40.3 19.7 187.5 16.2 46.9 16.6 39.8 41.9 209.6 70.7 26.6 85.0 36.9 210.8 314.6 78.9 17.5 17.6 27.9 16.6 501.1 37.6 22.1 30.1 35.6 32.9 55.6 31.1 146.4 19.7 64.4 108.5 42.9 23.4 82.6 22.9 20.2 91.7 33.9 7.8 12.5 181.8 29.4 67.6 78.9 12.7 21.2 49.1 82.6 19.6 41.0 9.4 39.4 22.3 20.9 42.5 26.4 84.5 36.3 26.8 51.3 84.4 13.2 16.8 127.1 27.0 86.1 9.0 53.7 21.8 33.0 92.0 14.0 59.1 52.7 4.9 0.0 14.4 0.0 0.0 10.9 34.9 46.0 44.8 46.0 90.8 226.4 201.6 71.0 29.3 76.2 370.9 30.9 109.7 20.3 45.8 30.0 53.3 154.3 176.8 139.8 181.5 1.9 27.6 2.3 29.3 61.0 63.6 91.6 31.5 781.6 28.5 42.1 91.6 44.9 59.4 31.6 45.5 49.6 39.5 193.5 302.9 279.1 30.7 16.2 116.0 435.1 9.6 29.2 285.4 55.2 126.5 157.1 96.4 50.4 193.5 91.9 25.5 80.6 32.0 133.9 54.7 75.0 22.1 20.6 113.3 32.9 97.0 69.5 44.5 130.7 30.4 204.7 228.8 125.1 76.0 65.9 90.2 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP4B ATP6B ENSG00000186009 "ATPase H+/K+ transporting subunit beta" P51164 13 113648804-113658198 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 305 "stomach 1: 1096.8" "Cell type enriched" "Detected in some" 76 "Gastric mucus-secreting cells: 145.8" "Cancer enriched" "Detected in some" 12 "stomach cancer: 8.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045400, HPA052649" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA045400: AB_2679314, HPA052649: AB_2681900" "unprognostic (9.92e-2)" "unprognostic (2.19e-1)" "unprognostic (2.66e-1)" "unprognostic (4.86e-1)" "unprognostic (6.43e-3)" "unprognostic (7.81e-3)" "unprognostic (1.95e-1)" "unprognostic (3.22e-1)" "unprognostic (6.50e-2)" "unprognostic (6.65e-4)" "unprognostic (2.25e-1)" "unprognostic (2.78e-1)" "unprognostic (3.78e-2)" 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 3.5 0.3 0.0 0.0 0.0 0.3 3.3 0.0 0.2 0.2 0.1 0.4 0.1 0.4 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1096.8 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.5 0.6 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 ATP6V0A2 "a2, ATP6a2, ATP6N1D, J6B7, Stv1, TJ6, TJ6M, TJ6s, Vph1" ENSG00000185344 "ATPase H+ transporting V0 subunit a2" Q9Y487 12 123712353-123761755 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 75.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 13.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 51.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044279 Approved Supported "Vesicles,Plasma membrane,Focal adhesion sites" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Vesicles, Focal adhesion sites" "HPA044279: AB_10961274" "unprognostic (2.60e-1)" "unprognostic (8.79e-3)" "unprognostic (3.60e-2)" "unprognostic (1.50e-1)" "unprognostic (2.70e-1)" "unprognostic (2.29e-2)" "unprognostic (2.06e-4)" "unprognostic (1.40e-1)" "unprognostic (3.77e-2)" "unprognostic (1.75e-1)" "unprognostic (8.85e-3)" "unprognostic (1.63e-1)" "unprognostic (1.26e-1)" "unprognostic (7.48e-2)" "unprognostic (1.12e-1)" "unprognostic (3.47e-1)" "unprognostic (1.58e-1)" 6.6 4.4 5.6 7.0 6.2 10.4 5.7 7.4 6.5 4.7 6.9 5.5 8.7 6.0 3.9 4.3 4.8 3.8 4.7 6.0 6.0 3.8 4.2 6.3 8.3 6.6 5.8 4.1 5.7 3.7 4.9 3.7 6.5 4.7 5.8 6.7 7.6 4.0 6.5 9.4 7.0 5.1 5.6 6.6 8.8 4.9 6.2 7.5 4.8 3.5 8.2 5.3 4.5 7.9 4.8 10.3 12.0 17.8 9.2 7.0 6.7 6.2 6.2 5.4 5.8 6.9 2.7 18.0 4.2 7.6 5.5 9.0 16.1 6.2 4.5 11.4 10.2 27.9 9.2 5.4 10.2 16.8 51.0 6.7 4.4 5.9 7.4 9.0 5.0 15.0 14.5 3.4 8.1 8.4 15.4 24.8 11.5 6.6 6.5 15.7 9.9 6.4 8.3 10.4 7.2 13.6 9.3 6.9 9.4 6.6 5.9 14.4 8.3 8.0 3.1 10.8 9.1 10.8 12.8 14.9 9.4 12.1 6.5 6.3 0.7 13.7 1.7 0.9 1.0 0.9 1.7 1.5 0.8 3.7 1.6 1.8 2.0 1.7 1.5 2.8 1.0 0.8 5.6 6.2 7.4 6.5 6.0 6.0 6.6 5.8 6.5 5.6 6.2 7.9 13.0 6.4 11.0 3.9 20.4 10.1 10.8 4.6 11.4 20.5 7.9 5.3 8.8 12.8 8.3 9.2 12.5 5.2 27.9 17.9 0.0 8.1 10.2 11.0 11.9 10.6 13.2 50.3 21.2 10.9 5.7 11.3 18.3 12.3 75.3 8.7 18.2 11.4 8.4 11.8 19.3 9.8 2.0 9.4 17.2 4.5 8.7 11.3 1.8 7.5 13.2 9.0 25.7 10.6 17.1 9.2 9.0 9.4 19.7 15.7 11.1 4.0 13.5 28.8 6.6 12.4 10.9 23.6 12.6 9.6 14.2 6.8 21.8 5.7 11.4 11.4 ATP6V1H "CGI-11, SFD, SFDalpha, SFDbeta, VMA13" ENSG00000047249 "ATPase H+ transporting V1 subunit H" Q9UI12 8 53715543-53843558 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Host-virus interaction, Hydrogen ion transport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009532, HPA023421" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 8300 "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Actin filaments, Cytosol" "Plasma membrane" "CAB009532: AB_667834, HPA023421: AB_1845202" "unprognostic (1.67e-3)" "unprognostic (2.53e-2)" "unprognostic (1.41e-2)" "unprognostic (2.16e-2)" "unprognostic (2.38e-1)" "unprognostic (2.25e-2)" "prognostic unfavorable (7.81e-4)" "unprognostic (2.01e-1)" "unprognostic (1.95e-1)" "unprognostic (6.39e-3)" "unprognostic (1.56e-1)" "unprognostic (5.30e-2)" "prognostic favorable (1.46e-7)" "unprognostic (1.06e-1)" "unprognostic (3.37e-2)" "unprognostic (1.38e-2)" "unprognostic (1.64e-1)" 24.1 44.6 42.5 15.9 46.7 25.6 26.0 27.5 58.8 23.9 30.2 31.6 12.9 25.4 32.9 34.1 22.6 20.7 31.2 57.4 38.0 60.5 19.1 24.2 21.4 30.5 30.2 24.1 17.4 47.7 42.4 23.9 32.7 30.2 20.4 37.4 28.7 27.4 37.8 35.2 19.1 24.1 29.4 20.3 31.8 18.5 31.0 26.6 52.4 27.3 22.0 28.5 26.4 37.9 42.8 35.6 29.8 31.8 50.9 32.9 23.4 40.5 44.5 54.8 56.7 33.5 54.1 27.2 38.7 40.9 69.7 67.8 52.6 58.9 56.1 39.9 35.8 28.8 34.3 40.9 69.1 19.6 31.8 46.5 82.3 37.2 66.4 52.5 37.8 28.9 39.4 14.0 81.6 36.0 30.6 32.5 27.4 37.0 17.4 28.2 10.6 18.6 88.4 67.4 23.5 34.9 28.7 54.6 79.5 34.4 64.0 16.3 43.2 24.4 19.7 54.6 25.5 25.9 30.4 32.3 57.8 27.4 27.5 25.7 14.8 36.2 13.2 16.6 14.9 13.6 14.3 15.4 20.2 12.0 14.4 16.0 14.5 22.6 23.4 15.9 20.7 11.8 42.5 46.7 27.5 58.8 57.4 38.0 30.5 30.2 32.7 29.4 31.0 37.9 18.2 38.5 27.4 84.2 39.0 29.6 40.1 55.5 42.1 72.8 27.8 21.0 28.9 38.6 50.3 58.8 112.6 76.0 35.9 39.0 105.7 49.1 8.3 94.1 27.7 25.4 35.3 27.0 154.7 31.1 43.6 23.6 26.0 145.7 15.8 22.0 28.9 21.9 64.7 62.2 105.8 17.4 75.3 43.0 103.6 8.5 43.2 52.9 30.2 42.2 35.1 48.4 37.0 58.3 57.7 44.1 30.1 48.2 20.9 32.5 31.4 64.9 39.6 76.4 19.7 16.8 24.6 28.5 52.9 37.6 31.4 100.0 38.1 36.4 21.8 41.4 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATP8B1 "ATPIC, BRIC, FIC1, PFIC, PFIC1" ENSG00000081923 "ATPase phospholipid transporting 8B1" O43520 18 57646426-57803315 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hearing, Lipid transport, Transport" Translocase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 76.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 279.7;Intestinal goblet cells: 180.5;Paneth cells: 116.7;Undifferentiated cells: 185.7;Urothelial cells: 119.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 90.2;RT4: 168.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA018673, HPA018674" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA018673: AB_1845207, HPA018674: AB_1845208" "unprognostic (1.83e-1)" "unprognostic (1.32e-1)" "prognostic favorable (2.60e-4)" "unprognostic (8.81e-2)" "unprognostic (1.32e-3)" "unprognostic (2.06e-1)" "unprognostic (1.39e-1)" "unprognostic (1.02e-1)" "unprognostic (9.62e-3)" "unprognostic (1.97e-1)" "unprognostic (3.30e-3)" "unprognostic (4.55e-3)" "prognostic favorable (6.35e-4)" "unprognostic (1.88e-1)" "unprognostic (2.22e-1)" "unprognostic (3.25e-1)" "unprognostic (8.60e-3)" 9.1 5.4 1.3 8.5 2.0 1.2 9.5 3.6 3.9 16.3 3.0 76.2 30.3 5.9 3.5 14.8 10.6 18.0 4.4 1.7 1.1 6.6 7.7 8.3 2.2 2.1 1.1 2.1 23.3 9.7 2.7 6.9 2.0 17.6 61.7 0.6 20.6 11.5 1.9 8.4 38.2 8.3 1.0 4.6 46.1 0.6 1.9 1.5 22.0 1.8 3.6 30.0 13.0 3.0 32.0 10.7 0.1 0.6 10.5 19.2 11.9 62.6 63.6 67.4 40.4 8.0 24.3 1.5 19.3 90.2 22.3 44.9 0.2 13.9 64.3 0.2 1.1 0.2 2.6 2.5 2.2 0.4 0.6 2.9 12.6 20.8 34.0 39.5 33.0 0.3 0.3 0.7 34.1 15.6 0.1 0.3 0.3 35.5 3.3 0.3 0.2 0.0 7.9 168.1 0.8 0.7 1.3 32.5 0.1 0.5 10.3 0.6 35.3 48.3 2.0 7.7 14.2 0.4 0.4 0.5 1.1 0.4 2.8 0.2 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.4 0.1 0.2 0.6 0.0 0.2 0.1 0.0 0.0 1.3 2.0 3.6 3.9 1.7 1.1 2.1 1.1 2.0 1.0 1.9 3.0 25.9 19.2 27.0 11.1 4.1 7.8 66.7 20.6 10.2 0.7 28.4 10.4 5.4 27.1 48.9 40.5 0.0 25.6 0.6 279.7 0.0 27.0 2.8 26.3 4.0 30.8 68.4 0.4 61.2 53.1 2.7 7.1 98.4 40.1 4.5 0.9 33.2 19.1 2.4 6.7 11.7 180.5 22.4 2.8 4.0 0.4 0.3 1.0 7.2 37.5 0.9 0.1 0.0 20.6 10.7 38.5 116.7 0.0 0.9 70.8 58.2 0.2 44.7 1.2 13.1 2.8 20.7 0.3 1.5 28.0 16.3 10.9 1.7 2.3 185.7 119.2 ATP8B2 "ATPID, KIAA1137" ENSG00000143515 "ATPase phospholipid transporting 8B2" P98198 1 154325525-154351304 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.8;Excitatory neurons: 28.5;Inhibitory neurons: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 2.8;T-cells: 3.7" "Cell line enhanced" "Detected in many" "ASC diff: 120.9;fHDF/TERT166: 112.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046680, HPA061103" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" "Nucleoli, Cytosol" "HPA046680: AB_2679749, HPA061103: " "unprognostic (1.68e-1)" "unprognostic (3.68e-1)" "unprognostic (8.40e-2)" "unprognostic (5.16e-2)" "unprognostic (4.52e-1)" "unprognostic (8.17e-2)" "unprognostic (2.27e-2)" "unprognostic (6.93e-3)" "unprognostic (2.57e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.60e-4)" "unprognostic (2.82e-1)" "unprognostic (1.89e-3)" "unprognostic (7.77e-3)" "unprognostic (6.58e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (5.29e-5)" 17.2 9.5 8.2 22.7 7.8 5.4 14.0 18.8 11.0 28.7 20.7 17.8 12.5 39.2 17.7 11.0 30.8 18.2 15.2 10.8 9.2 6.3 3.4 18.0 25.4 8.9 8.1 35.3 5.9 10.5 19.3 15.3 9.6 18.9 9.1 2.1 7.2 21.2 3.5 8.5 17.6 39.7 5.6 19.5 14.5 16.3 8.8 18.4 15.0 7.4 19.6 19.7 17.9 7.7 2.1 15.6 20.0 20.5 120.9 80.4 0.3 41.8 77.4 26.1 30.5 0.3 0.6 1.9 21.4 112.4 17.7 9.2 23.0 5.5 19.3 46.6 16.8 19.7 20.4 18.9 37.2 0.1 14.8 53.4 1.3 40.6 38.7 35.6 40.0 25.1 37.6 47.8 22.7 21.8 36.2 2.5 43.7 0.4 17.4 39.9 12.7 71.5 5.3 0.4 17.4 22.7 11.3 2.8 30.3 28.3 14.9 15.3 34.7 40.2 19.2 51.4 13.5 58.0 75.7 11.1 14.1 2.2 24.7 2.8 0.0 1.7 1.1 0.0 0.7 0.3 1.7 1.9 0.0 0.2 1.4 1.2 0.0 0.5 0.0 0.3 3.7 0.5 8.2 7.8 18.8 11.0 10.8 9.2 8.9 8.1 9.6 5.6 8.8 7.7 6.4 3.2 4.5 26.8 7.7 2.5 1.4 0.9 0.0 4.5 1.9 2.3 6.2 0.0 1.9 0.0 2.1 0.1 16.0 0.1 0.0 1.6 0.6 6.5 20.5 9.0 0.0 0.4 28.5 0.2 0.5 12.8 0.5 2.4 7.6 10.8 13.6 0.8 0.4 8.4 31.7 0.2 0.0 1.0 4.2 1.4 11.5 1.3 7.2 4.7 0.9 3.4 7.2 4.0 4.2 0.9 0.0 14.7 13.9 5.6 0.0 0.2 4.4 0.5 0.0 9.5 11.2 2.6 4.3 0.6 1.6 0.3 17.2 6.7 0.1 0.8 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 ATXN3 "ATX3, JOS, MJD, SCA3" ENSG00000066427 "Ataxin 3" P54252 14 92044496-92106621 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021976, HPA024123, HPA069338" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB021976: , HPA024123: AB_1845133, HPA069338: AB_2686124" "unprognostic (1.06e-2)" "unprognostic (2.93e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-2)" "unprognostic (5.76e-2)" "unprognostic (1.57e-1)" "unprognostic (1.42e-1)" "unprognostic (9.85e-3)" "unprognostic (1.69e-1)" "unprognostic (6.75e-2)" "unprognostic (1.04e-2)" "unprognostic (3.06e-2)" "unprognostic (2.03e-2)" "unprognostic (8.94e-3)" "unprognostic (4.22e-1)" "unprognostic (1.64e-1)" "unprognostic (1.11e-1)" 9.0 5.9 3.8 5.7 4.2 9.9 6.8 4.9 5.0 7.5 3.3 7.3 3.7 6.4 4.3 10.3 6.0 6.5 5.3 3.6 5.0 5.6 9.6 6.8 7.7 6.2 5.7 7.1 4.5 6.4 4.0 7.0 6.2 6.0 6.8 3.9 5.8 5.5 3.3 12.9 4.8 8.6 4.3 5.6 5.2 9.3 4.3 8.0 5.9 5.9 9.8 9.0 8.0 4.9 8.6 16.7 14.6 13.6 20.9 20.1 28.4 9.7 15.4 11.9 16.5 12.3 23.2 17.6 18.5 15.8 14.1 14.6 11.6 21.0 26.3 20.0 3.5 7.4 8.0 18.2 17.3 13.5 12.6 16.5 18.1 20.9 21.8 15.9 18.7 19.4 10.1 12.5 18.2 33.1 14.0 11.9 10.4 28.5 13.6 11.0 27.0 9.9 15.3 19.4 5.3 8.8 23.1 9.5 13.3 19.6 18.1 9.1 10.0 11.7 17.0 7.5 5.2 10.8 19.8 16.2 8.3 12.9 6.9 13.5 14.3 10.8 6.1 16.5 7.4 7.7 7.0 6.9 16.2 10.6 7.8 8.8 12.2 8.7 23.0 9.3 8.1 6.3 3.8 4.2 4.9 5.0 3.6 5.0 6.2 5.7 6.2 4.3 4.3 4.9 55.0 16.0 12.4 33.6 27.6 25.4 28.6 29.8 19.4 35.4 16.9 18.4 19.3 15.7 20.0 42.3 50.1 20.3 31.5 13.8 15.6 25.8 19.8 20.3 34.9 53.0 16.1 30.3 36.1 17.3 29.8 34.6 18.3 22.5 24.6 25.9 49.6 21.1 22.4 26.9 28.6 16.4 12.2 35.1 27.2 26.8 67.7 30.0 23.2 28.1 48.0 20.4 29.9 39.2 51.5 19.6 16.1 65.1 20.1 31.9 16.6 17.7 16.0 46.7 46.0 51.9 38.2 39.1 57.2 21.6 30.3 25.3 28.8 24.8 18.9 28.2 ATXN7L3 DKFZp761G2113 ENSG00000087152 "Ataxin 7 like 3" Q14CW9 17 44191805-44200113 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064316 Supported Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Plasma membrane" "HPA064316: AB_2685243" "unprognostic (2.37e-2)" "unprognostic (8.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.86e-3)" "unprognostic (6.74e-3)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.21e-3)" "unprognostic (9.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.40e-1)" 23.3 24.6 51.0 32.6 58.1 45.0 21.3 28.0 76.6 28.4 12.0 26.8 31.2 28.3 25.9 40.1 26.5 24.1 24.9 58.5 35.9 29.2 28.0 25.2 37.2 58.3 42.4 25.5 24.2 24.5 35.1 30.7 60.6 26.9 24.3 21.5 27.9 27.7 25.3 31.2 29.6 25.8 33.0 36.3 28.3 36.9 48.3 42.1 29.1 22.6 35.5 28.7 28.1 54.1 40.9 67.7 73.3 47.8 50.1 49.5 39.8 49.1 54.3 61.4 57.7 52.0 45.1 71.3 38.6 55.5 56.6 43.9 57.7 46.1 51.2 83.6 57.2 48.5 58.9 58.5 49.3 76.3 94.3 56.1 69.0 51.7 54.1 65.0 60.3 54.2 66.1 43.5 40.8 30.7 92.3 58.0 55.1 36.7 52.5 62.8 70.9 54.1 49.8 57.9 46.5 59.0 29.0 25.4 50.5 101.4 62.0 67.1 52.2 61.5 63.8 32.3 46.5 52.1 73.8 86.4 40.6 32.6 36.8 0.4 1.2 1.5 1.7 0.7 1.0 1.4 1.4 1.1 1.0 2.4 1.0 1.3 2.5 0.5 0.9 1.6 0.8 1.1 51.0 58.1 28.0 76.6 58.5 35.9 58.3 42.4 60.6 33.0 48.3 54.1 14.3 3.2 3.7 5.5 9.4 7.1 5.6 8.0 8.6 17.4 13.7 9.1 6.2 5.7 6.6 18.4 16.7 6.3 11.3 22.2 3.9 7.1 14.7 14.0 16.9 10.5 14.4 4.0 9.1 13.1 6.7 7.2 8.6 20.7 2.5 9.9 10.4 8.1 8.4 28.6 8.6 11.0 4.1 11.1 10.9 40.0 9.0 10.0 5.4 8.4 12.7 8.6 5.2 3.0 5.3 15.0 13.6 5.7 5.5 8.6 14.1 4.6 7.6 13.9 6.6 6.7 9.3 6.3 8.5 11.0 10.5 13.7 10.0 10.4 11.2 9.1 AVEN PDCD12 ENSG00000169857 "Apoptosis and caspase activation inhibitor" Q9NQS1 15 33858782-34075155 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 44.0;Oligodendrocytes: 86.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 2.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020863 Approved Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Actin filaments" Centrosome "HPA020863: AB_1845219" "unprognostic (1.54e-3)" "unprognostic (1.99e-1)" "unprognostic (8.93e-2)" "unprognostic (5.77e-2)" "unprognostic (5.57e-2)" "unprognostic (2.05e-1)" "unprognostic (1.18e-1)" "unprognostic (6.32e-3)" "unprognostic (1.70e-1)" "unprognostic (1.40e-1)" "unprognostic (4.14e-3)" "unprognostic (1.79e-1)" "prognostic unfavorable (5.29e-10)" "unprognostic (7.66e-3)" "unprognostic (2.40e-1)" "unprognostic (1.63e-1)" "unprognostic (2.84e-3)" 13.7 11.4 8.5 7.2 8.6 4.4 10.8 8.9 10.1 11.4 10.5 15.2 7.4 12.5 5.2 12.3 11.3 6.4 28.5 8.2 9.2 5.5 16.9 7.2 4.8 9.2 9.0 10.5 20.8 3.0 5.8 12.4 9.4 9.4 9.4 2.5 7.9 9.1 31.1 11.2 7.5 12.5 8.8 6.5 12.3 10.7 9.0 6.9 5.6 13.6 7.9 16.2 10.8 9.1 16.4 26.3 26.0 8.6 21.4 24.1 14.7 41.1 36.2 31.9 19.9 7.2 11.3 15.2 24.8 34.8 24.2 10.4 12.2 26.9 25.7 14.6 7.7 26.1 15.9 20.5 31.5 26.6 18.2 19.8 50.9 18.4 45.8 38.6 35.2 7.6 26.6 21.1 45.6 17.3 10.5 46.1 11.9 22.2 8.5 15.7 14.6 32.2 26.4 21.0 13.4 16.8 22.6 11.6 11.4 10.7 12.6 29.4 24.5 27.7 9.5 12.0 34.6 21.2 17.7 31.1 13.3 31.0 15.2 0.0 0.2 0.0 0.5 0.6 0.6 0.4 0.5 0.2 0.2 0.1 0.2 0.3 0.0 0.5 0.2 2.3 0.9 0.1 8.5 8.6 8.9 10.1 8.2 9.2 9.2 9.0 9.4 8.8 9.0 9.1 9.0 3.2 5.3 16.6 5.6 5.7 8.7 1.8 3.4 5.6 7.5 9.0 32.7 2.8 0.8 0.0 6.2 11.0 10.5 7.4 0.0 2.9 13.8 4.4 14.3 10.2 4.8 9.5 21.8 8.6 44.0 8.5 5.6 5.6 0.0 14.7 8.6 19.1 7.4 8.4 24.1 7.7 0.0 4.1 4.4 6.5 7.5 5.0 3.6 22.5 3.5 10.9 7.2 26.7 86.6 7.0 5.2 10.5 15.6 21.5 9.4 4.6 1.5 5.3 6.6 4.9 9.7 6.2 7.4 12.9 9.7 9.4 6.5 23.1 6.0 14.7 AVPI1 "PP5395, VIP32, VIT32" ENSG00000119986 "Arginine vasopressin induced 1" Q5T686 10 97677424-97687241 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 100.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 246.7;Granulosa cells: 385.5;Langerhans cells: 326.1;Late spermatids: 278.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 119.7;HHSteC: 119.1;hTCEpi: 230.5;SK-MEL-30: 194.5;U-2197: 134.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037649 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA037649: AB_10671879" "unprognostic (4.57e-2)" "unprognostic (3.28e-2)" "unprognostic (3.04e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-2)" "unprognostic (7.34e-3)" "unprognostic (8.56e-3)" "unprognostic (2.29e-3)" "unprognostic (1.23e-1)" "unprognostic (3.91e-3)" "unprognostic (4.04e-1)" "unprognostic (2.03e-1)" "unprognostic (8.66e-2)" "unprognostic (3.83e-3)" 32.1 41.5 18.5 6.5 25.4 5.0 21.2 21.9 23.2 38.1 16.2 24.6 14.0 11.2 4.7 26.2 18.9 10.4 22.4 18.3 19.8 12.1 46.9 22.5 2.4 23.7 20.2 85.6 9.4 5.6 19.2 16.9 21.9 26.3 18.9 25.5 22.7 16.6 12.5 100.7 15.6 5.3 22.4 20.8 30.5 16.0 20.8 2.0 9.1 3.9 4.4 25.5 46.0 29.5 38.8 99.8 0.5 14.3 20.2 9.1 20.0 18.5 100.7 25.0 37.5 18.8 47.2 0.8 13.0 10.5 18.0 40.0 7.6 32.3 9.4 1.0 8.9 2.6 119.7 52.6 119.1 2.6 3.0 14.6 230.5 18.7 49.1 22.8 3.4 3.6 5.7 2.0 14.0 33.4 1.7 3.1 3.5 10.6 9.3 1.3 11.3 1.5 24.9 20.9 1.7 4.0 63.9 22.7 194.5 3.2 17.2 3.1 5.5 5.9 11.7 134.4 4.6 4.4 3.3 0.8 22.2 8.1 3.8 0.0 6.2 2.3 4.2 5.7 2.0 2.8 2.8 3.1 11.1 2.0 3.0 3.7 0.5 2.0 0.5 2.3 2.6 2.9 18.5 25.4 21.9 23.2 18.3 19.8 23.7 20.2 21.9 22.4 20.8 29.5 6.3 19.2 19.0 0.7 8.0 96.0 87.6 246.7 145.1 9.6 13.6 16.8 9.7 52.9 63.4 38.6 6.2 149.6 15.4 137.5 43.0 18.8 60.9 33.2 17.1 11.4 31.8 2.1 3.6 24.1 64.8 23.4 58.1 57.9 6.3 385.5 34.2 42.4 41.8 13.5 4.3 70.4 48.8 21.7 326.1 278.5 10.2 49.6 83.6 0.0 6.4 128.2 2.1 0.5 4.4 43.3 100.6 14.7 5.9 55.2 109.0 11.2 16.7 14.6 6.6 10.2 19.3 3.5 4.9 68.0 108.4 194.7 19.0 10.9 100.6 106.3 AXIN2 "DKFZp781B0869, MGC126582" ENSG00000168646 "Axin 2" Q9Y2T1 17 65528563-65561648 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 33.7;Extravillous trophoblasts: 102.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 33.4" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 3.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 27.2;CACO-2: 52.3;Hep G2: 78.8;OE19: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012283, CAB017783" Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Cytosol "CAB012283: AB_2290204, CAB017783: " "unprognostic (1.31e-2)" "unprognostic (1.29e-1)" "unprognostic (1.05e-2)" "unprognostic (3.45e-3)" "unprognostic (4.48e-1)" "unprognostic (9.81e-2)" "unprognostic (1.12e-2)" "unprognostic (1.82e-1)" "unprognostic (4.57e-2)" "unprognostic (8.84e-3)" "prognostic favorable (6.58e-4)" "unprognostic (1.98e-1)" "unprognostic (1.42e-1)" "unprognostic (3.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.74e-1)" "unprognostic (1.25e-1)" 8.7 10.9 6.8 5.4 6.9 0.9 5.3 7.9 7.9 17.2 5.5 12.3 7.1 23.9 5.9 5.9 19.8 6.6 8.0 9.4 6.2 3.7 2.7 17.0 3.5 8.5 7.9 15.0 4.2 4.2 6.2 18.4 5.3 14.0 14.6 3.4 5.2 8.9 14.6 14.9 7.4 17.3 7.3 7.4 13.6 6.7 11.0 17.3 12.3 7.8 2.7 11.4 8.0 5.6 0.0 13.9 27.2 0.5 9.6 4.1 12.0 0.4 1.3 0.9 1.7 52.3 5.0 1.0 1.7 8.0 1.0 0.4 5.7 0.1 1.9 2.4 3.1 0.0 2.4 78.8 1.0 0.1 0.1 2.4 2.1 2.2 0.6 1.6 2.4 5.1 0.2 1.2 1.4 0.3 13.9 0.1 5.3 86.9 0.6 9.9 1.6 0.1 2.6 0.3 8.4 5.5 0.5 0.3 4.8 20.0 1.0 0.3 6.3 5.3 9.6 7.6 1.7 0.1 3.0 3.8 2.5 0.6 2.6 3.2 0.0 0.0 0.1 0.0 0.4 0.5 1.1 0.2 0.0 1.8 2.3 0.4 0.0 1.0 0.0 0.0 0.0 0.3 6.8 6.9 7.9 7.9 9.4 6.2 8.5 7.9 5.3 7.3 11.0 5.6 2.4 0.0 9.0 9.8 1.0 11.2 2.2 1.0 11.4 3.7 5.2 8.1 8.7 1.5 8.1 0.0 4.2 18.1 0.7 15.2 0.0 1.4 33.7 7.8 15.1 5.3 5.4 0.0 8.4 0.9 102.6 10.3 5.6 16.5 0.0 3.1 1.1 2.0 3.8 1.7 8.7 17.4 0.0 0.0 7.5 17.5 6.5 0.6 17.8 9.4 1.0 3.3 0.0 8.0 2.0 0.8 18.9 10.9 0.9 2.9 1.9 0.9 1.3 2.5 13.1 1.6 10.6 6.2 12.9 3.3 5.5 14.2 4.6 3.6 19.8 1.3 AXL "ARK, JTK11, Tyro7, UFO" ENSG00000167601 "AXL receptor tyrosine kinase" P30530 19 41219223-41261766 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Differentiation, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Oncogene, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 147.2;Kupffer cells: 187.5;Langerhans cells: 185.5;Prostatic glandular cells: 123.4;Sertoli cells: 210.4;Smooth muscle cells: 171.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 11.1;plasmacytoid DC: 25.7" "Group enriched" "Detected in many" 12 "dendritic cells: 25.7;NK-cells: 11.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 501.2;U-251 MG: 540.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032501, HPA037422, HPA037423, HPA075217" Uncertain Supported "Vesicles,Plasma membrane,Actin filaments" NA Yes 12100000 72000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Actin filaments" "CAB032501: AB_2062572, HPA037422: AB_10672347, HPA037423: AB_2675470, HPA075217: " "unprognostic (2.20e-1)" "unprognostic (2.02e-1)" "unprognostic (6.79e-3)" "unprognostic (1.01e-1)" "unprognostic (1.40e-1)" "unprognostic (8.49e-3)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (3.15e-2)" "unprognostic (2.82e-2)" "unprognostic (9.57e-3)" "unprognostic (1.98e-1)" "prognostic unfavorable (2.53e-7)" "unprognostic (1.16e-3)" "unprognostic (1.52e-2)" "unprognostic (5.56e-2)" "unprognostic (4.83e-3)" 43.6 18.8 17.5 15.5 22.6 1.7 26.6 19.7 17.7 36.1 12.4 42.5 11.7 34.4 8.7 17.6 25.4 22.4 26.7 16.6 18.8 9.8 15.0 25.9 6.2 26.8 20.6 24.7 6.3 10.7 7.3 34.2 22.1 19.2 12.6 5.8 10.6 24.6 9.4 20.0 19.0 37.1 20.9 37.7 21.4 18.6 24.0 7.2 16.6 11.3 5.0 32.5 25.2 21.9 408.0 160.0 9.7 1.3 34.6 34.7 0.5 314.5 280.2 450.9 278.2 8.5 185.5 0.2 124.7 501.2 235.3 33.3 0.4 211.8 384.8 0.7 0.3 0.0 100.4 6.3 125.0 0.3 0.3 26.4 3.8 266.7 409.5 254.8 169.8 0.1 15.8 0.5 284.6 0.5 0.2 0.4 4.1 1.0 76.3 0.2 165.3 0.3 202.3 0.2 0.1 0.1 81.5 0.6 1.8 57.4 0.9 7.2 351.8 317.8 214.6 307.7 540.8 0.5 0.9 1.0 211.5 0.5 241.8 1.5 0.3 0.2 0.1 0.4 0.2 0.1 0.3 0.1 6.0 0.1 0.3 0.3 0.3 11.1 0.2 25.7 0.4 0.3 17.5 22.6 19.7 17.7 16.6 18.8 26.8 20.6 22.1 20.9 24.0 21.9 13.5 9.6 3.6 35.9 1.9 41.7 88.3 10.3 3.4 0.5 2.3 14.2 8.6 1.5 4.4 5.5 0.0 4.2 0.8 0.1 0.0 6.9 8.7 6.0 45.8 17.7 0.0 0.0 0.8 0.2 2.1 147.2 1.5 5.4 0.0 17.3 11.0 1.2 28.8 1.7 1.1 0.1 2.0 187.5 185.5 5.5 61.5 61.4 26.6 30.9 3.1 26.8 0.0 11.1 0.5 14.5 0.1 79.7 0.8 123.4 0.3 0.1 2.8 1.2 210.4 38.1 171.1 1.9 2.0 1.2 29.1 11.5 3.6 2.5 0.1 28.0 B2M ENSG00000166710 Beta-2-microglobulin P61769 15 44711487-44718851 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins, Transporters" Immunity "Amyloidosis, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 31919.3;NK-cells: 24726.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002572, HPA006361" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1790000000 2100000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 3: Monocytes - Immune response regulation" "Golgi apparatus, Plasma membrane" Cytosol "CAB002572: AB_563434, HPA006361: AB_1078278" "unprognostic (9.45e-2)" "unprognostic (5.63e-2)" "unprognostic (3.02e-1)" "unprognostic (8.14e-2)" "unprognostic (1.18e-1)" "unprognostic (4.82e-2)" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (2.69e-2)" "unprognostic (1.12e-1)" "unprognostic (2.44e-3)" "unprognostic (2.02e-2)" "unprognostic (4.77e-2)" "unprognostic (2.39e-1)" "unprognostic (5.25e-2)" "unprognostic (1.97e-2)" "unprognostic (2.17e-2)" 3160.2 3214.7 697.6 5686.5 705.1 7839.2 2606.9 711.8 1145.0 2539.9 789.6 5139.0 5180.7 2192.2 1735.6 2283.9 1648.3 4948.8 2327.2 651.0 769.9 2462.6 6206.2 6159.2 9311.8 889.5 763.2 1945.7 1310.9 1940.5 318.4 3502.0 815.3 2345.0 5593.5 139.3 5657.1 1784.5 931.7 3015.6 5693.3 2545.3 838.3 7896.1 4878.2 615.6 771.9 4217.4 2340.8 2026.5 5333.4 5753.1 549.4 909.5 1735.4 378.9 226.0 633.6 4348.7 4719.4 1662.5 2045.5 4961.9 3609.7 6561.4 425.3 5417.9 554.8 2567.9 1948.8 2410.2 2537.0 497.2 878.7 1226.2 4762.2 435.9 2956.9 2263.6 600.3 3609.3 2074.5 3328.6 2735.9 609.8 1075.7 1044.4 2442.6 1884.1 965.4 611.9 3649.1 2195.5 476.9 1518.4 3213.8 206.5 629.8 1014.3 2240.2 1926.6 4789.2 2425.5 3486.4 254.1 179.1 1288.4 1571.2 1338.5 394.3 655.3 6180.6 2548.7 4531.4 676.5 5389.2 2193.3 4771.7 7118.6 1683.1 5384.6 3783.6 2567.3 48105.4 18117.1 33178.9 20639.1 17775.0 20836.8 15768.0 23783.0 22245.1 9978.8 11988.4 17122.9 22791.8 50453.6 18779.6 19034.9 12052.6 29659.1 56957.2 697.6 705.1 711.8 1145.0 651.0 769.9 889.5 763.2 815.3 838.3 771.9 909.5 12048.3 3387.8 3505.1 28.7 8472.8 7843.7 3197.1 8420.8 1628.8 33.3 2399.5 2015.2 1068.8 3593.1 5347.4 2100.3 27.1 1354.6 14028.8 8753.6 1038.9 13898.6 43.1 2073.7 2414.0 8385.6 2266.0 2087.2 7.3 9034.5 4397.5 3691.1 1981.7 2282.2 3029.5 1270.6 6835.7 3832.6 11985.7 5.0 22.0 5982.6 8701.4 12536.8 14507.0 158.8 3018.0 10687.9 6744.8 368.2 31919.3 322.0 24726.3 95.0 129.2 10115.7 7085.6 1688.8 11026.6 5300.4 18327.7 3122.5 8367.9 52.5 4016.7 2055.2 4107.1 64.2 72.1 1541.4 8619.8 804.8 14266.2 3229.8 3063.4 8248.6 B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193178730-193186613 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2;gallbladder: 15.0;heart muscle: 21.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 46.6;Cardiomyocytes: 34.4;Excitatory neurons: 27.6;Inhibitory neurons: 28.3;Leydig cells: 31.7;Peritubular cells: 21.1" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 8.4" "Lineage enriched" "Detected in single" 53 "T-cells: 8.4" "Group enriched" "Detected in some" 4 "AF22: 18.3;ASC TERT1: 8.1;LHCN-M2: 12.6;WM-115: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA078659: AB_2686887" "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" 0.3 1.2 13.4 0.7 15.3 0.2 0.3 4.9 17.1 0.2 2.3 1.0 0.9 0.1 1.0 0.6 0.2 15.0 21.0 17.2 7.1 0.9 0.2 1.8 0.2 5.8 7.4 10.4 0.2 0.0 0.5 0.3 5.8 4.7 1.2 6.6 0.1 5.1 0.1 0.2 3.0 0.1 7.0 0.8 1.3 0.7 8.5 0.0 1.0 0.3 0.9 1.4 0.3 15.9 0.0 0.0 18.3 0.0 0.5 8.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.6 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.2 0.0 8.4 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 13.4 15.3 4.9 17.1 17.2 7.1 5.8 7.4 5.8 7.0 8.5 15.9 0.6 0.0 0.5 1.6 0.9 0.3 0.1 0.0 0.6 46.6 0.0 0.1 34.4 11.5 0.0 1.8 4.2 0.0 0.2 0.1 0.0 0.1 0.0 0.3 1.3 1.1 3.0 0.8 27.6 0.0 0.0 2.0 0.0 0.9 2.5 0.4 0.7 0.1 0.3 8.4 28.3 0.7 0.0 0.6 0.3 0.7 31.7 0.7 0.0 4.7 0.0 2.4 0.0 12.1 9.3 0.5 0.1 21.1 0.4 0.1 3.4 0.1 2.2 6.2 0.0 0.3 1.2 0.0 0.0 0.3 0.3 0.0 4.9 0.3 0.5 0.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 119.1;pancreas: 271.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 118.9;Early spermatids: 99.9;Late spermatids: 343.0;Oligodendrocytes: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" 15.4 16.0 34.3 8.0 68.5 3.3 11.7 68.7 44.0 18.3 11.9 13.7 6.1 19.7 8.8 13.5 15.9 19.1 11.4 34.3 44.5 14.8 25.6 14.4 5.1 89.7 67.0 20.5 271.5 18.5 10.7 13.8 76.6 13.4 7.6 44.7 11.0 18.3 12.5 11.4 7.7 21.3 61.6 12.4 9.8 11.2 59.9 3.8 12.2 9.1 5.0 12.4 14.3 119.1 11.5 10.7 22.9 37.3 80.9 82.3 1.0 62.9 44.4 24.4 19.0 4.5 16.4 1.4 14.6 88.3 18.4 17.9 24.3 12.1 20.5 3.1 12.1 6.0 17.3 5.1 36.5 2.5 1.7 68.1 20.2 29.7 31.8 68.0 21.4 3.8 2.7 1.1 46.5 33.4 2.5 2.1 15.5 10.6 25.9 6.4 11.6 1.6 12.2 5.9 31.7 36.7 22.5 2.6 5.9 23.5 26.2 7.6 31.4 45.2 5.0 48.2 19.4 0.7 1.0 1.1 23.8 2.0 34.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 34.3 68.5 68.7 44.0 34.3 44.5 89.7 67.0 76.6 61.6 59.9 119.1 12.1 19.2 10.1 16.3 0.3 4.7 4.1 3.4 9.1 53.7 8.7 9.0 8.7 18.6 13.3 5.5 118.9 1.0 0.1 2.0 5.9 7.4 99.9 5.1 32.1 8.3 21.7 1.7 24.9 20.0 1.3 19.5 3.1 8.9 2.5 15.8 6.8 38.6 9.4 57.2 32.0 5.1 2.0 17.2 7.7 343.0 19.3 7.9 3.6 14.0 4.0 17.9 0.0 22.1 99.8 4.3 6.3 22.2 0.1 2.4 1.7 6.3 3.4 55.2 6.6 18.1 14.2 3.4 1.7 10.6 3.4 0.8 1.2 68.0 4.5 3.4 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BAIAP2L1 IRTKS ENSG00000006453 "BAR/IMD domain containing adaptor protein 2 like 1" Q9UHR4 7 98291650-98401090 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 58.8" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 108.1;Prostatic glandular cells: 114.7;Urothelial cells: 147.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 72.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "HPA019484: AB_1845265, HPA021257: AB_1845266, HPA023874: AB_1845267, HPA029503: AB_10602330" "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.00e-1)" "unprognostic (2.95e-1)" "unprognostic (2.80e-2)" "unprognostic (8.31e-3)" "unprognostic (4.56e-2)" "unprognostic (1.34e-2)" "unprognostic (9.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" 5.8 20.7 1.5 6.2 1.5 0.4 7.8 1.3 1.7 10.1 3.1 23.0 28.6 2.8 1.4 29.2 11.6 15.5 5.2 1.4 2.1 13.9 33.4 14.0 1.4 1.7 1.7 1.3 31.2 13.1 13.0 10.2 1.8 26.2 21.4 0.6 23.6 2.6 2.8 19.9 25.4 2.6 1.5 1.9 58.8 9.8 1.8 2.1 14.9 1.6 4.6 16.8 17.1 1.8 43.2 33.6 0.9 0.7 0.0 1.5 55.0 10.9 7.1 5.6 4.1 47.0 62.9 1.8 15.9 4.1 47.4 37.3 15.6 46.1 5.0 0.2 20.3 0.0 14.3 27.0 6.7 0.0 14.7 1.5 61.0 3.2 44.4 12.3 0.2 0.1 26.4 0.1 4.8 36.1 0.1 0.1 26.3 61.8 18.5 0.1 0.5 7.0 35.2 37.2 23.5 4.6 25.3 72.2 12.8 35.3 20.2 1.0 1.4 8.3 39.6 1.6 5.1 0.9 13.1 21.8 0.9 5.4 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.5 1.3 1.7 1.4 2.1 1.7 1.7 1.8 1.5 1.8 1.8 16.9 12.8 22.9 23.5 0.8 16.7 64.8 31.5 14.2 0.6 17.4 7.6 2.3 30.0 36.3 22.0 4.2 11.8 5.5 100.3 9.8 60.8 33.1 25.2 3.0 11.2 32.2 2.7 23.1 77.6 78.4 2.2 108.1 33.4 0.0 4.5 0.7 16.6 2.4 1.7 26.1 53.6 18.3 0.3 1.7 52.5 0.9 1.0 8.8 37.5 2.6 1.2 0.0 26.7 31.4 102.6 84.7 0.7 0.6 114.7 35.3 2.4 58.6 0.8 0.0 1.9 6.7 50.0 56.3 22.4 19.5 12.2 1.9 0.2 44.7 147.8 BANK1 "BANK, FLJ20706" ENSG00000153064 "B cell scaffold protein with ankyrin repeats 1" Q8NDB2 4 101411286-102074812 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 24.2;lymphoid tissue: 96.4" "Cell type enriched" "Detected in many" 10 "B-cells: 455.9" "Cancer enhanced" "Detected in many" "prostate cancer: 6.9" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 14 "memory B-cell: 310.4;naive B-cell: 253.0" "Lineage enriched" "Detected in many" 16 "B-cells: 310.4" "Cell line enhanced" "Detected in some" "Daudi: 13.6;HEL: 10.6;HL-60: 9.6;U-266/70: 31.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA037002 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 19000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA037002: AB_10672383" "unprognostic (1.59e-2)" "unprognostic (2.08e-2)" "unprognostic (6.43e-2)" "unprognostic (1.60e-1)" "unprognostic (1.28e-3)" "unprognostic (1.73e-2)" "unprognostic (4.89e-2)" "unprognostic (1.62e-2)" "unprognostic (1.01e-1)" "unprognostic (9.97e-2)" "unprognostic (4.25e-2)" "unprognostic (7.89e-2)" "unprognostic (2.80e-1)" "unprognostic (2.18e-1)" "unprognostic (2.75e-2)" "unprognostic (6.09e-3)" "unprognostic (1.75e-1)" 8.5 3.6 0.6 35.1 0.6 6.2 2.2 1.5 0.9 2.3 0.2 2.8 2.4 0.8 3.2 0.8 2.3 3.0 0.7 0.5 0.7 3.2 0.3 8.1 82.2 0.8 0.8 0.1 0.5 0.4 1.5 0.8 0.9 5.8 3.3 0.2 2.4 4.7 0.1 0.7 24.2 1.0 0.9 56.1 7.4 3.0 1.0 9.7 12.9 0.2 96.4 7.6 0.7 0.6 0.0 3.0 0.0 0.0 3.4 1.4 0.1 0.1 0.1 0.4 0.6 0.1 4.6 13.6 1.2 0.0 0.0 0.2 0.1 1.5 0.4 0.0 0.0 10.6 2.6 0.0 0.1 9.6 0.0 0.6 0.4 0.0 0.0 1.2 0.1 0.0 0.1 4.0 0.6 0.5 0.0 0.6 0.0 0.4 5.7 0.2 0.6 0.0 0.4 6.1 2.6 0.0 0.3 0.2 0.0 0.1 0.5 2.5 1.3 0.0 0.6 0.0 0.0 31.0 0.0 2.2 0.1 5.3 0.0 10.8 1.7 19.7 0.4 0.5 0.1 310.4 0.1 0.2 10.5 253.0 0.1 0.1 0.9 1.5 0.2 5.2 0.2 11.3 0.6 0.6 1.5 0.9 0.5 0.7 0.8 0.8 0.9 0.9 1.0 0.6 3.5 44.8 27.1 6.8 455.9 0.1 2.2 0.5 0.0 0.2 1.7 0.4 0.5 0.0 10.0 3.7 0.0 2.1 5.8 0.0 0.0 0.2 2.8 13.1 1.0 1.3 0.0 6.1 7.3 0.2 0.6 1.4 6.1 15.2 1.3 0.1 0.0 0.1 1.5 0.0 1.6 0.4 2.0 2.9 25.1 2.0 0.0 13.0 5.4 4.7 2.8 1.8 1.0 1.0 1.3 4.1 1.3 0.4 13.7 4.4 0.2 4.2 2.2 0.1 0.0 0.1 0.8 1.9 5.6 0.8 1.1 0.3 12.9 2.1 1.1 4.3 BASP1 "CAP-23, CAP23, NAP-22, NAP22" ENSG00000176788 "Brain abundant membrane attached signal protein 1" P80723 5 17065598-17276843 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 486.3;epididymis: 303.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 345.6;Extravillous trophoblasts: 362.9;Langerhans cells: 489.4;Muller glia cells: 796.9;Syncytiotrophoblasts: 738.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 128.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 128.5" "Cell line enhanced" "Detected in many" "GAMG: 467.0;HeLa: 800.8;SiHa: 830.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045218, HPA050333" Enhanced Enhanced "Plasma membrane" NA NA 63000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA045218: AB_2679263, HPA050333: AB_2681090" "unprognostic (3.35e-2)" "unprognostic (3.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.25e-11)" "unprognostic (1.95e-3)" "unprognostic (1.04e-1)" "unprognostic (3.61e-2)" "unprognostic (1.70e-1)" 35.3 13.8 235.9 73.6 257.0 87.6 14.0 103.0 486.3 56.9 79.9 12.5 7.3 37.3 303.3 10.9 11.4 29.2 13.9 247.3 210.9 15.1 17.2 36.5 80.9 134.7 153.1 36.6 3.7 3.4 21.2 92.1 184.3 79.7 10.8 74.3 13.2 21.6 2.3 22.0 22.2 33.4 107.7 76.5 22.7 2.9 157.1 24.1 11.3 6.8 91.5 57.9 27.3 281.8 0.1 125.6 152.7 0.2 71.7 76.1 227.1 161.7 50.9 127.9 135.0 6.1 0.1 51.3 22.4 112.0 467.0 10.6 98.2 109.2 164.8 21.3 57.9 0.4 800.8 0.3 158.9 101.3 1.4 131.2 132.7 145.6 121.0 163.9 140.1 0.2 0.4 0.5 138.2 183.7 0.3 92.5 115.7 0.3 39.6 0.1 0.5 28.0 46.5 31.3 99.3 21.3 830.7 72.3 0.2 336.5 0.3 101.9 187.7 169.3 0.6 14.2 26.1 1.7 0.2 27.1 171.2 123.0 23.1 25.0 3.1 25.3 0.0 1.5 0.0 5.4 0.0 0.0 4.9 7.9 0.0 0.0 128.5 1.8 2.1 0.5 0.3 0.8 235.9 257.0 103.0 486.3 247.3 210.9 134.7 153.1 184.3 107.7 157.1 281.8 8.0 9.6 4.8 22.2 158.7 215.9 88.0 21.3 58.1 54.8 9.8 10.2 1.6 0.0 15.8 9.2 12.5 155.0 3.8 0.6 0.0 0.6 0.9 98.4 345.6 30.2 0.0 18.1 254.0 3.4 362.9 102.6 23.4 156.4 27.3 18.1 35.7 2.5 53.8 244.0 125.3 0.7 12.2 227.9 489.4 0.0 0.6 298.5 28.4 53.4 275.1 796.9 1.0 115.1 23.7 1.0 0.2 0.0 173.0 121.0 0.0 0.3 93.5 58.4 0.0 2.0 66.2 0.4 3.4 21.0 58.8 738.5 11.9 8.3 1.8 13.2 BBOF1 "C14orf45, CCDC176, FBB10" ENSG00000119636 "Basal body orientation factor 1" Q8ND07 14 74019349-74082863 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 38.6" "Group enriched" "Detected in many" 4 "Early spermatids: 239.3;Endometrial ciliated cells: 166.4;Late spermatids: 111.3;Respiratory ciliated cells: 177.8;Spermatocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 16.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA003090, HPA003136, HPA075108" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "HPA003090: AB_1845571, HPA003136: AB_1078330, HPA075108: " "unprognostic (1.84e-2)" "unprognostic (1.31e-1)" "unprognostic (5.71e-2)" "prognostic favorable (6.34e-4)" "unprognostic (1.11e-2)" "unprognostic (1.29e-2)" "unprognostic (1.28e-2)" "unprognostic (2.08e-1)" "unprognostic (1.85e-1)" "unprognostic (4.62e-2)" "unprognostic (1.01e-1)" "unprognostic (3.89e-1)" "unprognostic (1.40e-3)" "unprognostic (6.14e-2)" "unprognostic (2.57e-1)" "unprognostic (7.93e-2)" "unprognostic (6.04e-3)" 4.9 2.8 5.8 2.3 6.3 6.5 7.3 5.5 9.0 6.5 15.9 7.1 2.0 7.1 14.6 5.2 22.5 5.7 4.4 6.3 5.8 9.7 2.2 6.8 1.7 9.7 9.8 5.1 2.8 5.0 10.7 2.4 8.3 5.5 3.5 24.3 3.8 7.1 2.3 3.1 2.4 5.5 8.0 1.4 3.4 38.6 6.2 2.8 13.2 3.3 2.1 5.0 3.1 6.6 5.4 3.1 1.3 8.7 5.7 12.5 1.1 4.6 6.5 4.6 4.3 1.1 3.7 5.3 1.2 5.7 2.0 1.3 1.8 0.8 5.2 0.8 1.0 0.6 3.1 1.2 4.8 2.7 0.3 6.1 4.2 10.3 1.3 7.3 1.7 9.7 2.9 0.9 3.4 4.3 8.5 1.3 0.4 0.5 2.1 3.0 3.4 0.9 7.9 1.4 5.2 3.3 9.0 3.6 2.6 1.3 9.2 0.2 3.8 5.7 4.0 7.6 1.3 1.9 4.9 3.3 16.7 0.3 1.6 1.1 0.0 0.1 1.5 0.0 1.8 0.5 1.4 1.0 0.1 0.6 1.9 1.5 1.0 1.1 0.0 2.4 0.3 1.2 5.8 6.3 5.5 9.0 6.3 5.8 9.7 9.8 8.3 8.0 6.2 6.6 3.8 12.8 8.1 0.0 1.4 0.0 3.8 0.0 4.0 7.8 15.8 8.0 0.0 7.2 30.3 3.7 29.2 1.8 3.9 1.8 15.6 9.0 239.3 166.4 15.1 3.1 2.4 39.6 0.0 3.5 2.6 7.4 2.0 18.2 1.3 4.3 3.6 4.5 2.3 6.7 0.0 2.7 0.0 1.6 0.0 111.3 10.8 3.9 0.0 0.0 0.8 5.7 4.1 0.0 0.0 3.0 0.2 6.0 0.7 2.5 1.0 23.5 177.8 29.9 0.0 4.3 4.0 149.2 14.7 1.3 0.0 1.0 2.3 4.1 0.9 3.4 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BCAR3 "AND-34, NSP2, SH2D3B" ENSG00000137936 "BCAR3 adaptor protein, NSP family member" O75815 1 93561741-93847150 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 72.5;Basal prostatic cells: 149.0;Extravillous trophoblasts: 75.0;Urothelial cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0;memory B-cell: 1.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTERT-HME1: 159.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014858 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" Centrosome "HPA014858: AB_1845302" "unprognostic (9.16e-2)" "unprognostic (2.06e-2)" "unprognostic (2.79e-2)" "unprognostic (1.09e-1)" "unprognostic (9.60e-3)" "prognostic unfavorable (8.41e-4)" "prognostic unfavorable (5.42e-4)" "prognostic unfavorable (8.92e-7)" "unprognostic (2.44e-1)" "unprognostic (3.66e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.51e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.13e-1)" "unprognostic (1.14e-1)" "unprognostic (7.05e-2)" "unprognostic (1.87e-1)" 31.0 10.6 17.7 6.6 20.9 1.0 18.5 19.3 15.3 10.0 21.1 15.3 13.4 5.7 3.6 8.1 9.5 7.5 13.1 14.8 18.7 15.9 11.9 14.2 13.8 21.1 20.6 11.4 4.2 4.0 4.6 17.0 18.9 8.9 16.6 1.5 21.9 9.5 24.4 15.6 12.9 8.0 19.0 4.8 16.2 6.3 21.7 4.3 10.4 21.1 13.0 13.6 9.8 17.8 56.0 23.4 43.5 3.4 18.4 14.4 37.1 56.9 98.3 45.9 28.1 4.0 40.9 9.0 18.9 88.1 59.4 34.0 1.3 73.5 39.7 4.0 1.3 0.0 16.2 10.3 33.1 0.4 0.2 17.3 79.5 47.5 159.7 44.1 51.1 1.1 1.6 0.3 125.7 8.6 1.0 0.2 13.6 24.5 79.7 3.7 62.7 1.3 120.4 70.1 1.5 3.6 27.4 29.1 36.1 16.8 32.9 2.2 60.8 67.3 17.5 29.2 76.0 4.5 2.1 1.2 10.1 0.2 25.2 2.0 0.0 0.0 0.0 0.4 0.0 1.8 0.0 0.0 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.7 0.1 0.0 17.7 20.9 19.3 15.3 14.8 18.7 21.1 20.6 18.9 19.0 21.7 17.8 26.9 3.2 7.2 72.5 10.2 9.8 149.0 11.3 2.8 0.9 7.9 13.5 7.1 11.5 11.7 14.7 0.0 27.5 2.5 30.8 27.4 11.3 11.3 13.3 2.6 17.9 14.9 0.4 5.2 6.3 75.0 6.3 15.8 16.6 3.8 33.7 5.7 10.3 11.9 21.9 11.2 20.7 8.2 5.3 12.7 12.8 10.2 8.3 19.6 64.6 9.4 4.0 0.0 3.0 2.1 28.0 22.0 1.2 8.9 36.3 25.8 23.7 18.1 0.4 72.3 23.8 19.9 4.2 3.7 4.8 10.2 18.9 3.7 8.3 10.3 106.1 BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane" "HPA020856: AB_1845320" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (3.64e-1)" "unprognostic (3.68e-2)" "unprognostic (6.80e-3)" "unprognostic (3.87e-3)" "unprognostic (6.12e-2)" "unprognostic (8.90e-2)" "unprognostic (1.60e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (8.75e-5)" "unprognostic (8.67e-2)" "unprognostic (3.62e-2)" "unprognostic (2.37e-1)" "unprognostic (2.56e-1)" 8.5 8.5 3.8 14.7 3.9 18.2 9.5 3.9 5.1 8.3 5.0 11.9 10.5 9.9 3.2 13.4 9.5 6.5 9.4 3.6 3.8 7.8 16.6 9.6 20.6 4.4 4.2 9.7 15.5 4.5 2.7 10.3 4.1 11.3 7.3 1.7 11.7 5.0 14.0 8.5 11.9 6.8 4.1 16.7 11.7 10.1 4.1 17.3 7.6 13.5 15.8 9.6 8.7 4.3 105.2 63.7 49.8 94.8 12.6 12.6 56.9 58.2 23.3 57.2 60.6 89.2 55.4 58.4 26.7 20.2 32.4 49.7 46.3 39.4 30.7 74.1 97.4 53.1 43.5 62.0 11.4 56.6 62.2 15.5 19.0 64.3 18.2 11.5 38.7 79.2 138.8 73.3 30.8 59.1 67.6 91.8 62.4 61.8 77.4 86.6 54.3 62.7 24.8 52.0 0.9 29.4 59.5 79.0 41.8 35.6 33.0 70.3 22.8 64.1 75.2 45.5 96.4 61.2 102.4 114.3 27.2 78.0 64.3 11.0 7.4 17.0 12.5 12.2 14.6 14.8 13.2 12.3 6.5 14.6 12.8 13.1 10.9 15.8 8.6 25.9 14.4 6.3 3.8 3.9 3.9 5.1 3.6 3.8 4.4 4.2 4.1 4.1 4.1 4.3 10.2 9.6 13.1 3.3 22.1 32.2 37.4 23.3 14.2 1.0 35.2 34.2 5.0 10.0 16.5 5.5 0.0 70.3 18.2 14.6 7.9 25.7 8.3 17.0 11.5 13.2 6.7 18.5 0.2 25.8 126.3 16.2 9.2 20.1 9.5 18.9 11.0 13.1 37.6 0.0 0.2 15.7 18.3 12.6 16.1 6.4 6.5 15.5 26.6 1.0 22.1 3.5 24.7 0.0 1.6 34.5 16.6 6.0 44.3 20.5 6.5 10.4 12.6 1.2 13.1 14.0 15.1 11.6 22.3 19.7 19.5 55.7 15.7 11.7 23.3 27.7 BCL6B "BAZF, ZBTB28, ZNF62" ENSG00000161940 "BCL6B transcription repressor" Q8N143 17 7023050-7030290 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 37.8;Endothelial cells: 45.0;Hepatic stellate cells: 23.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.2;HMC-1: 53.2;HUVEC TERT2: 96.2;TIME: 38.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA059147, HPA075112" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA059147: AB_2683928, HPA075112: AB_2732279" "unprognostic (5.61e-2)" "unprognostic (9.43e-3)" "unprognostic (2.33e-2)" "unprognostic (2.12e-1)" "unprognostic (1.40e-1)" "prognostic favorable (8.56e-5)" "unprognostic (2.81e-1)" "unprognostic (2.28e-2)" "unprognostic (4.81e-2)" "unprognostic (1.80e-1)" "unprognostic (6.10e-2)" "unprognostic (1.76e-1)" "prognostic unfavorable (4.04e-4)" "unprognostic (7.14e-2)" "unprognostic (1.11e-1)" "unprognostic (4.29e-2)" "unprognostic (4.26e-2)" 29.8 5.6 8.1 5.7 7.0 0.1 15.4 6.2 9.2 5.7 4.4 4.4 3.2 7.7 0.7 3.8 5.1 13.4 23.3 6.5 6.9 13.4 4.0 28.9 5.5 7.8 7.1 2.9 3.8 3.1 5.5 19.9 7.3 4.5 2.2 0.6 4.0 3.5 11.5 4.4 4.9 7.7 6.6 13.0 4.3 2.0 10.1 2.0 12.0 14.7 2.1 7.9 4.8 6.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 18.2 0.0 0.0 0.5 0.0 53.2 0.0 0.0 0.0 0.1 0.0 96.2 0.2 3.4 0.4 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 38.2 0.8 0.2 0.1 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.2 9.2 6.5 6.9 7.8 7.1 7.3 6.6 10.1 6.7 37.8 3.2 4.2 0.0 0.5 2.2 0.0 0.0 0.0 0.0 0.2 0.3 2.9 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.3 45.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.1 23.6 0.2 0.1 0.0 0.0 0.2 0.0 1.9 2.3 0.0 0.0 0.3 3.6 4.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.2 0.0 0.9 0.8 0.6 1.5 0.4 1.3 0.1 0.2 0.9 0.0 0.5 BCORL1 "CXorf10, FLJ11362" ENSG00000085185 "BCL6 corepressor like 1" Q5H9F3 X 129981107-130058071 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.6;HAP1: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031775, HPA031777, HPA068568" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane" "HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007" "unprognostic (8.07e-2)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (2.20e-5)" "unprognostic (4.58e-1)" "unprognostic (1.68e-3)" "unprognostic (1.96e-3)" "unprognostic (5.56e-3)" "unprognostic (2.39e-1)" "unprognostic (8.02e-2)" "unprognostic (4.46e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (9.18e-2)" "unprognostic (2.60e-2)" "unprognostic (3.09e-1)" "unprognostic (1.41e-2)" 3.5 3.1 2.4 2.6 2.5 5.6 2.1 4.5 2.6 3.5 0.4 2.9 2.6 4.5 2.2 2.6 4.3 2.0 2.8 2.4 2.7 2.6 2.0 2.9 1.7 2.9 2.1 5.5 4.5 5.8 2.6 11.3 1.9 3.2 2.0 2.0 3.3 3.7 3.3 2.9 2.8 4.3 1.4 2.8 2.2 6.5 2.1 2.3 4.5 3.3 1.7 2.6 2.6 1.9 3.4 8.0 18.7 29.6 10.6 8.0 5.3 4.5 5.2 5.7 6.5 9.6 2.2 1.5 9.9 8.8 5.5 2.0 44.2 1.8 5.2 3.4 6.7 16.2 3.9 3.1 5.2 3.8 4.8 4.9 3.6 11.0 0.6 8.3 6.8 5.2 7.7 16.4 3.6 1.9 6.0 11.3 5.2 2.6 5.9 12.6 7.5 2.2 3.0 0.4 3.2 10.9 2.3 0.7 3.0 9.4 6.7 5.9 5.9 4.5 6.0 5.7 4.5 5.1 10.1 2.5 2.9 7.8 2.2 0.0 0.3 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.2 2.4 2.5 4.5 2.6 2.4 2.7 2.9 2.1 1.9 1.4 2.1 1.9 5.4 0.0 2.8 6.8 2.9 11.9 2.8 2.2 10.8 1.7 12.5 7.5 7.1 4.3 1.9 7.3 0.0 14.1 6.1 3.7 0.0 3.0 0.5 3.7 7.0 7.9 12.0 2.5 4.6 1.1 4.8 6.9 2.6 4.7 7.0 4.3 4.6 2.8 3.2 8.4 4.4 2.4 2.0 2.2 5.9 1.2 4.7 2.7 7.2 5.6 3.0 2.3 4.1 4.5 8.5 2.6 1.9 3.8 3.2 3.8 4.2 2.3 2.9 1.3 6.6 8.0 6.1 3.4 6.9 9.2 11.5 93.4 4.9 0.9 3.6 2.8 BCR "ALL, BCR1, CML, D22S11, D22S662, PHL" ENSG00000186716 "BCR activator of RhoGEF and GTPase" P11274 22 23179704-23318037 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor, Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.7" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "K-562: 112.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010421, CAB018545, HPA038337" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "CAB010421: AB_2274682, CAB018545: AB_2063918, HPA038337: AB_10675795" "unprognostic (7.46e-3)" "unprognostic (2.43e-2)" "unprognostic (2.15e-3)" "unprognostic (1.16e-1)" "unprognostic (5.35e-2)" "unprognostic (1.45e-1)" "unprognostic (5.08e-2)" "unprognostic (1.44e-1)" "unprognostic (7.55e-2)" "unprognostic (1.81e-1)" "unprognostic (9.46e-2)" "unprognostic (2.39e-2)" "prognostic favorable (9.15e-10)" "unprognostic (1.47e-1)" "unprognostic (7.10e-2)" "unprognostic (4.10e-2)" "unprognostic (7.43e-2)" 19.4 11.1 34.3 11.0 65.7 34.6 17.4 15.9 30.7 14.3 10.6 11.7 10.0 12.3 16.1 24.5 12.1 9.3 12.2 45.0 22.2 21.1 13.8 18.6 13.7 27.1 26.5 9.4 14.6 20.6 25.0 10.3 24.1 11.8 7.6 7.4 18.3 10.1 5.8 23.5 10.2 8.8 20.9 11.4 16.1 11.0 35.0 14.7 19.7 5.7 10.8 15.3 14.3 14.1 47.6 20.1 30.3 31.2 17.7 12.1 45.6 16.8 15.7 15.2 12.2 35.6 18.7 32.9 30.5 14.4 14.7 47.6 3.6 46.8 4.3 63.3 32.3 28.8 27.7 28.6 22.9 26.9 14.6 10.2 31.1 22.8 19.8 27.0 53.6 23.3 112.5 15.1 7.0 31.3 25.4 21.4 25.8 37.4 19.5 32.9 12.4 21.7 23.7 29.6 27.7 26.3 30.7 26.1 12.6 19.3 16.6 21.7 61.4 9.1 1.0 14.9 14.0 3.4 14.8 11.7 23.4 20.1 14.3 0.0 0.5 0.0 3.1 0.2 1.1 0.6 1.5 1.6 0.4 0.6 1.3 1.7 0.5 1.5 0.5 0.4 0.8 1.4 34.3 65.7 15.9 30.7 45.0 22.2 27.1 26.5 24.1 20.9 35.0 14.1 19.3 9.6 11.5 51.2 4.5 15.4 11.9 18.2 6.2 22.9 17.1 9.9 7.5 17.2 20.9 18.4 22.9 14.0 23.9 17.7 9.8 14.4 5.6 22.1 8.0 27.8 19.9 5.5 24.6 16.6 6.8 7.1 11.7 31.4 10.8 9.9 70.6 22.1 7.2 23.5 20.7 13.9 12.2 9.3 11.1 13.5 8.7 9.2 5.4 18.7 6.6 13.2 15.5 32.2 7.0 27.7 8.1 5.7 10.7 11.8 10.7 18.2 12.5 9.4 0.0 4.0 6.8 2.7 7.3 9.3 15.8 10.8 10.3 10.0 13.7 13.3 BDKRB2 BK-2 ENSG00000168398 "Bradykinin receptor B2" P30411 14 96204679-96244166 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "urinary bladder: 41.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.3;Endothelial cells: 18.2;Fibroblasts: 25.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 49.2;BJ hTERT+: 94.5;U-87 MG: 39.7" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA003551, HPA050841" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA003551: , HPA050841: AB_2681254" "unprognostic (1.03e-1)" "unprognostic (7.90e-2)" "unprognostic (1.12e-1)" "unprognostic (1.83e-1)" "unprognostic (8.79e-3)" "unprognostic (2.68e-2)" "unprognostic (1.93e-1)" "unprognostic (4.66e-2)" "unprognostic (1.94e-1)" "unprognostic (2.84e-2)" "unprognostic (3.19e-1)" "unprognostic (1.72e-1)" "unprognostic (3.32e-3)" "unprognostic (3.11e-2)" "unprognostic (9.40e-2)" "unprognostic (9.90e-2)" "unprognostic (1.49e-2)" 14.0 1.4 0.8 5.5 1.0 0.0 5.8 3.8 1.1 15.6 0.9 12.4 7.9 6.7 2.4 17.2 7.2 20.8 1.2 0.9 0.8 13.4 0.7 2.5 0.3 4.9 1.3 1.0 9.4 0.9 0.8 1.3 5.0 4.8 12.2 0.0 3.5 6.2 0.9 5.4 9.7 10.2 1.0 0.1 4.9 0.2 1.5 0.9 3.6 1.8 1.7 41.1 15.4 1.2 1.7 6.1 0.1 11.0 16.2 49.2 0.0 5.5 94.5 3.2 3.7 0.3 10.4 0.0 0.2 8.7 3.7 14.8 0.0 2.4 2.8 1.2 0.1 0.0 1.1 0.0 7.8 0.0 0.0 15.1 7.5 9.4 4.7 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.1 0.1 20.4 0.0 0.0 2.2 0.0 3.2 0.0 3.4 1.1 1.8 15.6 0.1 2.1 1.0 0.0 0.0 0.3 0.3 3.3 0.1 0.2 0.0 0.0 39.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 1.0 3.8 1.1 0.9 0.8 4.9 1.3 5.0 1.0 1.5 1.2 8.2 3.2 3.1 0.0 0.0 9.2 0.7 5.3 6.8 0.0 0.2 0.5 0.6 10.0 11.6 9.2 0.0 1.2 0.0 19.3 7.9 11.5 0.0 7.5 16.1 18.2 7.1 0.0 1.8 3.8 3.6 25.8 1.1 4.6 0.0 0.0 3.3 0.2 0.2 0.0 0.4 7.2 8.2 0.0 15.2 0.0 0.9 0.4 5.4 0.0 0.0 0.0 0.0 1.0 1.9 6.9 6.2 1.2 0.0 1.0 10.6 0.2 12.5 0.0 0.0 4.5 1.2 0.0 0.0 15.3 5.8 4.0 0.3 0.1 0.9 2.9 BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 30.9;retina: 11.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.6;Excitatory neurons: 87.3;Horizontal cells: 42.1;Inhibitory neurons: 118.6;Oligodendrocyte precursor cells: 49.8" "Cancer enriched" "Detected in many" 6 "glioma: 4.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 28.8;fHDF/TERT166: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA031605: AB_10602395, HPA052973: AB_2682002" "unprognostic (4.27e-1)" "unprognostic (7.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.18e-6)" "unprognostic (2.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.82e-2)" "unprognostic (1.94e-2)" "unprognostic (9.84e-6)" "unprognostic (9.27e-3)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.98e-3)" 1.2 2.1 12.1 1.5 14.2 0.7 0.6 30.5 30.9 4.0 2.9 1.4 0.5 2.8 0.7 1.2 1.0 3.8 2.4 12.6 16.0 0.6 0.2 0.6 0.9 19.5 16.0 2.0 0.4 0.7 1.7 2.0 20.4 2.4 1.5 11.8 0.5 2.4 3.9 1.0 0.7 3.6 12.1 0.8 0.8 1.0 15.7 1.1 0.8 0.6 0.8 2.8 1.7 21.7 5.4 2.2 1.3 0.6 17.6 28.8 4.9 16.1 15.6 7.1 8.2 0.2 2.4 0.1 5.2 28.7 9.9 0.7 1.8 0.8 8.7 2.4 1.0 3.6 7.5 0.4 4.7 10.3 0.2 12.7 4.5 9.8 4.3 11.9 4.7 13.3 4.6 9.2 14.3 5.5 6.2 2.5 4.4 0.3 1.3 0.1 0.2 2.6 2.6 5.4 6.1 6.2 10.8 1.3 1.4 6.1 0.3 5.9 6.1 21.5 0.7 14.5 3.6 12.6 15.2 4.3 12.6 6.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 8.8 0.0 0.1 12.1 14.2 30.5 30.9 12.6 16.0 19.5 16.0 20.4 12.1 15.7 21.7 0.4 0.0 0.0 16.6 0.3 0.9 0.2 0.2 0.0 82.6 0.2 1.1 3.6 0.0 0.7 0.0 4.2 0.5 10.8 0.0 0.0 0.2 0.6 0.5 11.9 0.2 0.0 0.0 87.3 0.4 1.6 5.6 0.0 0.5 0.0 13.5 1.1 0.0 0.1 42.1 118.6 0.0 0.0 0.0 4.0 0.8 1.8 1.1 3.6 13.1 0.3 4.9 0.0 49.8 22.9 0.6 0.0 3.0 0.0 0.4 0.0 1.0 0.0 4.8 0.0 8.7 2.7 0.7 5.8 0.2 1.0 0.0 0.1 4.4 0.0 0.1 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133400056-133475222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "B-cells: 6.3;Melanocytes: 5.4;Plasma cells: 10.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "T-reg: 13.4" "Lineage enriched" "Detected in single" 43 "T-cells: 13.4" "Group enriched" "Detected in some" 6 "Daudi: 2.4;U-698: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA038464: AB_10672746, HPA062959: AB_2684912" "unprognostic (1.58e-3)" "unprognostic (7.47e-4)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (9.59e-2)" "unprognostic (4.04e-5)" "unprognostic (8.13e-2)" "unprognostic (5.57e-2)" "unprognostic (6.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.74e-2)" "unprognostic (4.70e-2)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.23e-2)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 1.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.4 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.3 0.1 5.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.6 0.0 1.0 0.1 0.1 0.0 BICD2 KIAA0699 ENSG00000185963 "BICD cargo adaptor 2" Q8TD16 9 92711363-92764833 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "mRNA transport, Protein transport, Translocation, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 63.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 83.6;Squamous epithelial cells: 103.2;Suprabasal keratinocytes: 130.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023013, HPA024452" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane, Cytosol" "HPA023013: AB_1845352, HPA024452: AB_1845353" "unprognostic (9.99e-3)" "unprognostic (1.98e-1)" "unprognostic (7.84e-3)" "unprognostic (2.81e-2)" "unprognostic (4.33e-2)" "unprognostic (2.86e-1)" "unprognostic (2.37e-2)" "unprognostic (1.47e-1)" "unprognostic (1.04e-1)" "unprognostic (6.54e-3)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.25e-1)" "unprognostic (2.26e-1)" "unprognostic (3.95e-1)" "unprognostic (1.39e-2)" 15.4 10.6 11.4 13.5 10.0 12.0 10.9 10.9 10.5 20.8 7.8 18.5 4.6 15.5 6.0 47.0 12.8 9.4 19.8 11.1 8.6 9.1 8.5 16.0 14.7 11.0 9.8 12.5 8.9 17.7 6.0 10.4 10.3 11.3 5.0 6.5 14.6 13.1 22.3 63.4 10.4 13.7 10.5 17.3 9.5 9.4 10.0 13.8 10.0 15.3 16.8 15.2 30.9 12.3 32.6 26.5 19.2 19.8 36.6 25.1 27.1 30.8 22.2 17.2 13.6 15.6 14.4 36.3 19.5 34.4 22.0 99.4 21.8 49.1 19.4 17.4 23.5 19.2 25.6 21.7 21.8 26.9 30.0 25.8 67.1 28.8 22.0 20.4 26.0 15.4 19.3 27.5 38.1 21.4 25.6 16.7 13.3 23.8 32.0 27.8 41.8 19.3 27.8 27.0 13.4 20.7 21.7 19.9 14.3 19.2 8.2 12.3 34.9 31.8 21.1 53.9 33.9 22.5 17.5 31.9 26.9 16.3 28.4 1.6 3.4 4.4 1.2 3.6 1.2 1.8 1.4 1.6 3.8 2.0 1.3 1.2 7.5 1.1 5.9 3.2 0.9 1.7 11.4 10.0 10.9 10.5 11.1 8.6 11.0 9.8 10.3 10.5 10.0 12.3 21.7 28.9 12.7 14.7 27.6 73.7 17.1 19.2 83.6 12.8 11.4 10.2 54.5 8.6 16.2 7.3 6.2 8.5 26.1 3.4 3.9 10.1 6.5 21.3 26.7 26.4 10.8 16.0 16.2 5.1 6.5 26.0 5.6 21.1 24.1 13.0 19.2 7.5 14.2 15.2 14.0 1.9 12.2 32.4 30.2 7.6 21.1 40.7 16.0 19.7 38.9 22.0 7.2 9.5 18.5 8.5 3.6 33.4 22.1 18.7 0.8 6.7 14.0 6.4 19.7 23.0 33.1 9.7 8.4 103.2 130.8 7.3 17.2 13.8 3.6 20.3 BIN2 BRAP-1 ENSG00000110934 "Bridging integrator 2" Q9UBW5 12 51281038-51324668 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 101.3;lymphoid tissue: 48.7" "Cell type enhanced" "Detected in many" "dendritic cells: 213.6;Extravillous trophoblasts: 172.1;NK-cells: 598.3;Syncytiotrophoblasts: 158.6;T-cells: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 82.6;HMC-1: 134.9;Karpas-707: 59.1;NB-4: 140.8;RPMI-8226: 55.4;THP-1: 117.4;U-937: 76.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038666, HPA038667" Enhanced Enhanced "Plasma membrane" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA038666: AB_2676139, HPA038667: AB_2676140" "unprognostic (8.44e-3)" "prognostic favorable (1.33e-4)" "unprognostic (2.48e-1)" "prognostic favorable (6.34e-4)" "unprognostic (4.63e-1)" "unprognostic (2.00e-3)" "unprognostic (1.21e-1)" "unprognostic (3.59e-2)" "unprognostic (3.72e-2)" "unprognostic (7.47e-2)" "unprognostic (5.71e-2)" "unprognostic (3.29e-1)" "unprognostic (1.65e-3)" "unprognostic (4.03e-1)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-1)" 7.1 3.7 3.6 32.5 3.5 101.3 3.3 3.6 4.8 3.6 4.2 8.9 6.2 2.1 1.0 3.2 3.1 9.2 2.3 3.2 3.8 3.0 7.3 16.4 41.9 5.9 4.7 1.7 1.3 1.0 1.1 19.5 5.1 2.1 9.2 0.4 3.4 2.0 1.5 1.3 10.7 6.4 4.4 48.7 7.4 7.9 6.4 48.6 2.2 4.3 36.4 10.1 2.0 6.2 0.1 0.1 0.0 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 38.3 0.1 82.6 0.0 0.0 0.0 34.7 134.9 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.1 59.1 0.0 0.5 24.2 140.8 0.1 0.1 0.0 0.0 0.0 55.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.2 117.4 0.1 0.0 0.1 0.1 0.1 31.5 0.1 8.0 0.1 76.8 0.0 663.7 199.8 245.9 281.0 311.8 227.7 49.2 188.9 237.2 107.2 74.0 145.4 193.5 380.1 235.6 411.7 39.7 267.1 479.5 3.6 3.5 3.6 4.8 3.2 3.8 5.9 4.7 5.1 4.4 6.4 6.2 1.5 3.2 17.6 1.3 54.0 0.6 0.1 0.0 0.0 0.1 1.3 1.5 0.6 1.5 2.6 1.8 0.0 103.9 213.6 4.5 17.6 0.1 26.5 0.1 0.2 3.5 1.2 16.2 0.7 0.0 172.1 2.7 3.1 0.2 56.3 0.1 8.2 1.2 56.9 0.0 0.6 8.5 0.0 73.0 22.3 25.7 0.6 111.2 1.8 44.0 77.6 0.0 598.3 2.0 0.6 0.0 4.6 0.4 51.3 0.1 0.1 1.6 3.7 0.1 0.0 1.0 0.9 39.6 11.3 0.4 0.6 158.6 165.7 0.1 5.4 0.1 BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.5" "Cell type enhanced" "Detected in many" "B-cells: 94.2;dendritic cells: 64.0;Microglial cells: 157.4;Plasma cells: 80.4;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "memory B-cell: 161.2;naive B-cell: 140.5;plasmacytoid DC: 231.5" "Group enriched" "Detected in many" 101 "B-cells: 161.2;dendritic cells: 231.5" "Group enriched" "Detected in some" 6 "Daudi: 68.7;REH: 168.4;RPMI-8226: 94.4;U-698: 251.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" 2.2 3.2 3.8 27.5 3.4 10.1 6.3 2.4 4.1 7.1 13.9 16.9 38.9 2.4 30.1 39.9 6.1 10.8 1.0 3.5 5.1 28.5 39.2 6.6 57.6 4.7 4.0 1.5 12.1 17.4 1.8 6.4 5.0 7.3 18.2 1.4 10.9 13.2 0.5 8.0 34.0 3.0 3.8 54.0 29.2 1.3 4.9 10.6 11.6 1.1 70.5 9.9 15.8 5.2 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 68.7 0.4 0.0 0.3 0.6 0.1 0.8 0.1 5.5 0.2 0.3 0.3 0.1 0.0 0.1 1.4 0.1 8.7 0.0 0.0 0.1 0.0 0.8 0.3 6.4 0.0 0.7 0.4 0.2 0.2 0.2 0.0 168.4 0.3 94.4 0.9 13.0 0.3 0.3 0.2 15.1 0.1 0.2 23.7 1.1 0.2 0.2 0.8 0.1 0.2 5.4 0.4 251.4 0.1 0.5 0.1 0.3 1.6 0.2 0.3 1.3 0.1 161.2 0.3 0.2 20.6 140.5 0.1 0.1 1.1 1.9 0.1 231.5 0.6 8.1 3.8 3.4 2.4 4.1 3.5 5.1 4.7 4.0 5.0 3.8 4.9 5.2 0.4 6.4 7.7 0.7 94.2 1.1 21.0 13.1 21.1 0.0 4.1 3.4 1.2 30.0 7.3 40.5 0.0 23.0 64.0 9.2 27.4 14.6 3.1 14.4 1.9 0.3 4.9 5.3 1.0 13.8 17.5 0.7 35.7 22.9 1.3 0.0 2.9 27.8 22.8 0.0 1.3 19.4 30.5 9.0 13.8 1.1 0.3 18.2 1.8 157.4 4.8 0.0 0.0 2.5 0.9 4.4 22.4 0.0 80.4 5.1 64.6 2.3 3.4 0.0 6.6 0.3 0.7 1.6 0.1 34.7 1.4 41.5 3.6 0.5 22.5 23.8 BLVRB "FLR, SDR43U1" ENSG00000090013 "Biliverdin reductase B" P30043 19 40447765-40465764 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 625.2" "Cell type enhanced" "Detected in all" "Erythroid cells: 3131.8;Hofbauer cells: 1099.2;Proximal enterocytes: 864.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "classical monocyte: 465.2" "Group enriched" "Detected in all" 7 "dendritic cells: 343.3;monocytes: 465.2" "Cell line enhanced" "Detected in many" "A549: 506.6;K-562: 506.8;OE19: 451.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041698, HPA041937" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No 370000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Nucleoplasm, Vesicles, Plasma membrane" "HPA041698: AB_10796781, HPA041937: AB_10794308" "unprognostic (1.86e-1)" "unprognostic (1.14e-2)" "unprognostic (4.23e-1)" "unprognostic (1.50e-1)" "unprognostic (2.08e-1)" "unprognostic (2.46e-1)" "unprognostic (9.92e-2)" "unprognostic (1.20e-2)" "unprognostic (8.56e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (3.90e-4)" "unprognostic (2.30e-1)" "unprognostic (2.70e-1)" "unprognostic (2.02e-1)" "unprognostic (5.11e-2)" "unprognostic (1.25e-1)" "unprognostic (3.92e-2)" 115.7 76.8 46.6 48.2 46.9 625.2 93.8 49.4 61.0 86.2 52.1 78.5 75.1 59.0 20.5 188.8 69.3 50.9 125.6 44.5 48.0 103.1 266.2 102.8 58.9 56.0 48.6 66.7 73.2 46.1 25.2 52.1 58.5 74.3 30.3 5.5 89.4 42.2 210.4 83.9 72.2 31.7 49.8 166.7 138.4 10.2 52.3 27.5 64.5 94.1 25.3 81.0 96.5 53.4 227.9 506.6 7.3 77.7 73.7 70.2 57.3 28.0 88.7 39.3 75.4 103.4 203.8 74.3 212.3 56.3 126.8 73.1 30.4 64.6 10.5 123.8 20.0 114.9 73.4 62.4 169.8 1.6 32.2 69.2 119.4 52.4 34.2 40.1 41.8 27.4 506.8 137.0 51.0 359.2 6.1 7.2 1.9 451.4 133.8 54.0 23.4 120.3 50.9 146.5 0.4 10.5 84.5 224.5 84.4 13.2 221.5 17.6 39.2 99.4 103.9 156.4 15.9 71.7 92.1 28.5 259.1 46.2 39.0 45.5 465.2 18.0 29.2 220.9 27.0 58.2 24.3 24.5 343.3 37.5 24.7 19.3 58.4 27.4 117.7 75.8 37.3 259.4 46.6 46.9 49.4 61.0 44.5 48.0 56.0 48.6 58.5 49.8 52.3 53.4 74.6 221.2 164.5 9.4 34.4 129.4 348.5 337.9 103.6 11.2 93.8 143.0 130.5 164.5 184.2 97.5 6.2 84.9 39.5 343.6 266.1 234.2 10.0 56.5 46.3 51.1 44.9 3131.8 5.2 267.3 94.7 112.5 280.3 83.1 43.1 31.0 57.1 680.8 1099.2 10.1 5.1 223.5 158.7 627.7 165.4 23.6 124.2 286.7 144.1 13.1 219.8 88.0 32.0 2.0 5.6 260.4 464.0 94.0 25.7 229.7 864.3 488.3 139.1 13.5 32.9 65.4 146.0 2.6 4.0 160.3 130.4 74.7 34.5 34.7 191.0 260.5 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BOC CDON2 ENSG00000144857 "BOC cell adhesion associated, oncogene regulated" Q9BWV1 3 113211003-113287459 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Basal squamous epithelial cells: 112.1;Fibroblasts: 55.4;Leydig cells: 84.8;Peritubular cells: 47.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 79.2;ASC diff: 113.6;BJ hTERT+: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB025806 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA No 7900000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Nuclear bodies, Plasma membrane" Nucleoplasm "CAB025806: " "unprognostic (6.89e-3)" "unprognostic (1.34e-2)" "unprognostic (2.62e-3)" "unprognostic (1.03e-2)" "unprognostic (5.03e-3)" "prognostic favorable (4.89e-4)" "unprognostic (8.66e-5)" "unprognostic (1.10e-1)" "unprognostic (1.19e-2)" "unprognostic (4.78e-3)" "unprognostic (3.42e-2)" "unprognostic (1.10e-1)" "unprognostic (3.65e-3)" "unprognostic (4.94e-3)" "unprognostic (1.11e-1)" "unprognostic (1.66e-1)" "prognostic unfavorable (1.18e-5)" 41.6 5.8 15.8 10.4 15.5 0.2 29.8 13.1 12.1 26.0 33.2 49.1 4.9 46.6 10.1 24.9 63.2 19.3 14.3 17.1 15.2 9.7 1.0 6.6 3.6 53.2 30.1 35.2 16.1 2.7 20.8 2.2 23.2 33.8 4.6 3.2 23.8 21.3 6.3 34.9 18.3 32.6 32.3 4.6 19.0 5.0 26.3 5.7 24.6 9.0 3.1 32.5 25.8 23.4 0.0 7.6 27.6 79.2 113.6 6.0 0.9 12.8 41.9 3.2 2.7 0.0 0.0 0.1 7.8 21.8 1.7 0.0 5.6 2.7 1.1 0.0 3.4 0.0 2.3 0.0 0.6 0.3 0.2 19.7 1.8 1.7 0.2 25.7 0.0 0.0 0.1 0.0 0.6 2.1 0.2 1.4 7.0 0.0 6.9 0.2 12.3 0.0 0.7 0.1 8.2 11.7 0.1 0.5 0.3 8.1 3.4 0.4 0.0 4.5 7.3 0.1 4.2 0.0 0.0 0.0 9.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 15.5 13.1 12.1 17.1 15.2 53.2 30.1 23.2 32.3 26.3 23.4 9.6 0.0 0.5 71.8 0.0 21.2 3.1 3.6 112.1 0.6 3.7 17.3 1.1 1.5 0.7 5.5 0.0 4.8 0.2 0.0 0.0 0.1 1.4 12.6 10.5 5.6 1.8 0.0 8.8 0.0 4.3 55.4 0.5 11.7 0.0 5.7 3.3 0.1 0.8 0.0 2.5 0.0 0.0 0.3 5.5 3.3 84.8 1.0 10.6 6.5 0.0 12.2 0.0 24.1 0.7 0.3 0.0 47.8 0.6 3.3 0.0 0.0 0.3 0.5 0.0 18.0 13.5 1.5 3.2 11.5 11.1 1.9 0.8 1.1 0.0 0.9 BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.6;T-cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "HPA039509: AB_2676550, HPA043627: AB_2678588" "unprognostic (1.82e-1)" "unprognostic (2.87e-1)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (6.78e-2)" "unprognostic (6.16e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-3)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-1)" "unprognostic (9.51e-2)" 6.3 8.1 5.1 2.5 7.1 6.2 6.1 5.2 6.4 6.6 2.3 5.8 1.7 5.8 5.8 8.0 5.7 2.4 7.1 4.1 5.8 5.9 8.5 6.5 2.9 5.6 5.4 4.9 7.2 3.8 7.1 2.7 6.2 5.9 2.2 2.8 5.4 1.9 8.4 8.7 4.7 3.0 4.7 6.2 5.9 9.1 5.4 3.1 4.6 3.3 3.9 5.6 6.8 8.2 3.9 4.1 2.9 3.0 6.4 8.7 3.3 3.4 3.9 4.1 5.1 10.0 3.9 4.9 2.0 5.5 2.9 2.7 5.0 4.9 4.4 14.0 4.5 2.7 3.9 5.7 6.1 2.9 3.8 4.9 3.5 5.6 6.5 6.5 4.9 6.1 3.8 6.6 5.4 8.4 4.2 3.0 9.0 4.1 2.6 3.4 4.1 5.3 5.1 2.6 3.6 4.1 3.3 3.0 7.5 9.6 2.3 3.1 4.1 2.7 6.1 3.5 3.1 3.4 3.2 11.1 5.8 4.4 4.6 2.8 6.1 9.5 10.1 10.3 11.9 7.7 11.5 11.2 7.3 5.9 7.6 7.7 6.7 12.4 6.7 5.1 14.2 7.0 5.1 7.1 5.2 6.4 4.1 5.8 5.6 5.4 6.2 4.7 5.4 8.2 11.1 9.6 2.3 0.0 37.9 0.0 11.9 0.0 10.8 16.9 10.5 8.4 0.0 10.0 2.5 7.3 12.5 9.2 42.6 2.2 9.8 9.5 5.6 8.8 9.0 6.7 4.9 5.9 0.0 12.4 11.7 8.3 19.9 8.9 2.5 7.4 6.1 5.1 14.5 13.5 0.0 3.8 0.0 11.0 0.0 3.9 5.3 26.3 0.0 0.0 19.0 12.5 14.4 0.0 0.0 9.5 3.5 7.2 33.0 9.1 10.3 14.1 2.9 16.6 26.3 8.3 8.1 23.4 8.6 14.6 0.0 14.5 39.5 7.5 4.6 8.3 BORCS8-MEF2B MEF2BNB-MEF2B ENSG00000064489 "BORCS8-MEF2B readthrough" 19 19145569-19192158 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 2.2;dendritic cells: 1.4;Gastric mucus-secreting cells: 1.5;Late spermatids: 1.1;Plasma cells: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-HME1: 2.0;U-266/70: 3.1" HPA004734 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 29: U-266 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: AB_10963939" "unprognostic (2.74e-1)" "unprognostic (5.77e-3)" "unprognostic (8.67e-2)" "unprognostic (3.88e-1)" "unprognostic (1.46e-4)" "unprognostic (1.88e-1)" "unprognostic (1.04e-2)" "unprognostic (1.66e-1)" "unprognostic (1.98e-1)" "unprognostic (3.75e-2)" "unprognostic (1.66e-1)" "unprognostic (7.20e-2)" "unprognostic (6.23e-2)" "unprognostic (1.25e-1)" "unprognostic (2.33e-1)" "unprognostic (7.78e-2)" "unprognostic (5.29e-2)" 0.2 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.6 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.4 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.6 0.2 0.2 0.1 0.3 0.3 0.1 0.1 0.1 0.1 0.0 0.6 0.2 0.2 0.1 0.3 0.2 0.3 0.2 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.8 0.0 0.1 0.1 0.7 0.2 0.1 0.1 0.4 0.3 0.4 0.0 1.4 0.3 0.1 0.0 0.5 0.5 0.2 0.1 0.2 0.1 0.5 0.1 0.1 0.0 1.0 0.0 0.0 0.0 0.9 0.1 2.0 0.5 0.2 1.3 0.1 0.6 0.0 0.7 0.7 0.1 0.0 0.1 1.6 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.0 1.5 0.0 3.1 0.6 1.7 0.3 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.6 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.2 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.1 1.4 0.8 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.4 0.0 0.2 0.1 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.5 0.0 1.2 0.0 0.6 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.6 0.0 BRK1 "C3orf10, HSPC300, MDS027" ENSG00000254999 "BRICK1 subunit of SCAR/WAVE actin nucleating complex" Q8WUW1 3 10115675-10127190 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 2544.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060391 Approved "Nuclear speckles,Cell Junctions" NA NA 170000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nuclear speckles" "Cell Junctions" "HPA060391: AB_2684272" "unprognostic (4.99e-2)" "unprognostic (3.48e-2)" "unprognostic (2.64e-1)" "unprognostic (3.83e-2)" "unprognostic (2.91e-1)" "unprognostic (9.60e-2)" "prognostic unfavorable (5.76e-5)" "unprognostic (2.49e-2)" "unprognostic (2.89e-1)" "unprognostic (1.09e-1)" "unprognostic (1.89e-1)" "unprognostic (1.37e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-1)" "unprognostic (9.40e-2)" "unprognostic (4.35e-2)" "unprognostic (7.75e-3)" 165.2 120.7 167.4 109.9 169.3 163.5 161.3 163.9 201.1 157.7 166.2 186.4 101.2 150.9 171.6 175.7 152.6 118.1 154.3 173.0 174.0 176.6 154.4 135.2 157.3 165.7 165.3 152.5 116.7 154.5 111.5 109.3 165.5 138.0 133.2 62.1 137.8 130.3 185.7 153.8 123.4 155.3 168.9 131.2 150.9 142.1 172.4 151.7 134.0 167.3 180.3 174.1 147.6 169.0 179.1 210.4 218.0 114.1 358.2 389.0 516.5 259.0 258.1 238.9 235.6 145.5 203.9 205.1 120.5 301.0 208.2 91.0 159.7 263.9 260.5 227.3 220.8 282.7 233.5 219.9 203.4 272.1 204.2 256.8 250.4 267.9 193.0 312.2 339.2 168.9 187.3 231.9 366.4 393.0 177.1 216.7 252.1 251.9 263.6 168.8 224.5 224.2 315.9 292.5 84.6 146.8 208.6 179.3 217.2 216.0 291.8 233.8 307.9 237.9 182.2 281.4 234.8 131.9 385.1 460.6 343.9 368.5 200.4 303.2 334.5 357.1 238.7 337.0 213.8 304.7 228.6 226.9 380.0 307.9 205.9 223.5 337.5 228.7 345.8 404.8 287.9 469.9 167.4 169.3 163.9 201.1 173.0 174.0 165.7 165.3 165.5 168.9 172.4 169.0 224.7 64.1 79.3 16.6 198.4 263.8 307.2 560.2 137.7 41.6 332.8 352.2 125.5 233.1 291.4 204.1 20.9 254.2 220.3 149.0 493.1 375.7 1034.0 145.6 152.2 273.7 298.7 191.2 33.5 361.6 282.9 223.2 119.3 127.3 173.3 152.3 272.4 255.0 442.7 47.1 20.7 211.3 307.2 373.9 380.3 2544.4 247.3 295.5 354.0 28.1 556.8 208.4 375.9 13.6 21.7 479.4 202.9 253.9 130.2 338.3 274.7 887.5 204.6 38.7 236.7 158.7 254.6 212.0 160.1 264.4 315.4 213.2 185.9 267.4 235.4 418.7 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 8.0 7.1 4.7 6.9 6.9 23.5 7.7 9.9 7.4 8.2 3.8 8.3 4.8 9.5 4.4 8.6 8.8 5.5 7.3 6.7 3.8 6.2 5.5 7.9 8.9 4.7 4.2 9.3 7.3 7.7 6.7 6.5 4.3 7.5 4.0 4.0 9.1 5.0 9.5 10.9 8.3 5.4 3.1 10.5 7.5 14.4 5.2 11.9 9.0 6.8 7.6 7.9 7.8 5.5 9.9 17.2 12.5 8.2 8.9 8.6 82.4 12.6 7.5 14.3 10.2 12.1 8.3 18.6 6.0 11.6 13.5 8.2 15.3 12.0 9.0 20.1 17.9 21.4 33.8 9.8 11.4 30.6 20.0 8.5 9.8 19.8 13.1 7.2 10.8 17.5 25.2 15.9 8.3 24.3 19.8 25.7 20.6 6.7 15.9 28.7 10.6 12.3 6.7 14.5 8.9 15.2 12.7 9.0 10.1 8.2 9.8 31.4 14.1 15.9 13.6 14.5 24.0 13.4 18.1 31.5 13.1 25.9 15.1 1.0 0.9 1.4 1.3 0.8 2.0 0.6 0.9 1.2 0.8 0.5 1.1 1.3 0.8 4.2 0.7 1.9 0.7 0.8 4.7 6.9 9.9 7.4 6.7 3.8 4.7 4.2 4.3 3.1 5.2 5.5 7.9 16.0 10.0 2.6 6.8 14.1 5.1 3.9 8.0 4.6 9.2 7.0 3.7 2.8 6.2 7.3 6.2 4.2 13.0 9.4 0.0 4.1 3.9 4.2 6.9 9.7 10.2 9.7 3.4 5.5 5.5 5.8 7.7 7.0 8.8 7.3 11.0 3.5 6.4 8.4 2.4 5.0 2.0 5.6 9.2 1.2 6.5 6.9 1.8 2.8 6.3 5.2 5.2 4.0 2.9 6.1 3.1 6.0 7.9 5.1 4.9 2.1 4.3 5.1 6.6 11.3 7.7 16.6 13.9 9.9 18.5 3.7 10.8 5.6 6.1 6.8 BRSK1 KIAA1811 ENSG00000160469 "BR serine/threonine kinase 1" Q8TDC3 19 55282072-55312562 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, DNA damage, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 141.8;pituitary gland: 53.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.8;Excitatory neurons: 30.1;Horizontal cells: 38.7;Inhibitory neurons: 27.6;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 29.4;Proximal enterocytes: 23.6" "Cancer enhanced" "Detected in all" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 56.4;SH-SY5Y: 51.8;WM-115: 46.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021212, HPA061719" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA021212: AB_1845455, HPA061719: AB_2684593" "unprognostic (1.42e-3)" "unprognostic (2.92e-2)" "unprognostic (1.20e-1)" "unprognostic (6.69e-3)" "unprognostic (2.71e-1)" "unprognostic (4.21e-2)" "unprognostic (3.06e-6)" "unprognostic (4.24e-1)" "unprognostic (2.06e-2)" "unprognostic (3.04e-1)" "prognostic favorable (1.02e-4)" "unprognostic (3.00e-1)" "prognostic unfavorable (7.98e-6)" "unprognostic (1.16e-1)" "unprognostic (6.61e-3)" "unprognostic (1.34e-1)" "unprognostic (2.09e-1)" 1.5 12.0 75.0 3.7 90.1 0.5 2.6 47.5 141.8 5.9 0.0 11.8 3.8 8.3 4.0 3.2 5.4 4.4 12.8 103.2 66.1 2.4 0.7 1.9 2.7 70.4 54.8 5.5 2.8 16.9 53.0 1.1 66.8 8.3 1.6 20.4 2.3 5.0 0.7 1.5 4.7 5.6 32.9 1.8 4.9 11.4 74.1 2.3 3.1 1.4 1.4 6.3 4.6 105.5 0.8 2.8 33.2 17.6 0.1 1.4 0.3 5.9 7.7 7.1 10.3 13.1 5.9 7.0 3.7 6.2 6.6 0.3 7.0 0.3 6.6 33.3 28.0 4.6 4.0 1.4 7.0 1.5 12.8 4.6 0.6 7.3 0.0 27.4 0.3 17.9 6.6 40.8 6.5 1.9 9.0 1.7 24.9 0.7 2.3 20.4 8.5 1.1 0.5 0.0 56.4 51.8 0.1 1.0 12.8 9.2 2.9 3.8 0.0 13.7 15.2 7.7 10.8 37.9 28.0 16.6 13.8 3.1 46.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 75.0 90.1 47.5 141.8 103.2 66.1 70.4 54.8 66.8 32.9 74.1 105.5 0.3 0.0 1.3 9.4 5.2 0.1 1.0 0.1 1.2 34.8 0.9 2.2 1.2 0.0 0.6 1.8 2.1 0.0 1.2 10.4 0.0 0.4 1.2 0.3 3.8 0.9 3.5 0.0 30.1 0.0 0.0 1.2 0.5 0.3 0.0 2.3 0.0 0.0 1.6 38.7 27.6 1.6 0.0 6.6 0.4 0.3 0.6 1.0 0.0 1.0 2.3 4.1 3.1 17.1 29.4 0.5 0.1 4.9 9.8 1.0 23.6 0.9 0.2 10.1 0.0 0.6 2.1 3.9 7.0 0.0 0.0 0.0 1.1 2.8 1.9 0.2 BSDC1 "FLJ10276, RP4-811H24.7" ENSG00000160058 "BSD domain containing 1" Q9NW68 1 32364633-32394731 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 37.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031358, HPA031360" Approved Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA031358: AB_2673841, HPA031360: AB_10601120" "unprognostic (1.42e-1)" "unprognostic (8.97e-2)" "unprognostic (2.91e-2)" "unprognostic (3.86e-2)" "unprognostic (2.48e-1)" "prognostic favorable (8.82e-5)" "unprognostic (3.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (9.56e-3)" "unprognostic (5.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.92e-3)" "unprognostic (2.68e-1)" "unprognostic (2.37e-1)" "unprognostic (2.07e-1)" 36.8 63.0 28.0 17.4 29.4 77.1 37.8 31.7 30.6 38.7 27.3 35.9 25.4 35.3 24.9 36.7 35.3 23.3 35.9 28.9 27.2 38.7 73.2 33.7 22.4 32.5 27.8 54.5 56.0 42.3 46.5 22.1 28.8 41.0 22.5 21.7 45.0 24.3 36.7 47.5 34.8 20.7 28.1 35.8 41.0 51.3 28.4 19.5 37.9 16.3 21.8 33.2 36.5 35.9 24.3 16.2 32.8 25.2 38.6 29.6 25.6 23.0 43.9 39.8 41.0 18.1 19.9 17.8 27.0 41.3 22.6 26.1 23.4 21.6 25.6 33.4 33.3 14.2 35.5 22.1 33.2 17.6 24.7 35.5 46.4 30.7 23.2 47.8 24.8 28.0 36.4 30.8 22.3 10.7 18.7 10.3 20.8 14.1 19.0 18.8 18.8 24.7 22.6 19.5 34.6 25.0 22.1 22.7 25.2 37.7 21.4 13.9 30.1 22.1 19.8 28.3 22.6 42.2 41.6 15.9 25.8 22.3 13.5 37.4 5.1 18.3 6.2 5.9 6.1 7.0 5.5 5.2 4.9 8.3 6.0 5.6 8.4 6.1 5.0 6.5 7.3 6.2 28.0 29.4 31.7 30.6 28.9 27.2 32.5 27.8 28.8 28.1 28.4 35.9 24.6 32.1 18.6 23.5 42.8 28.4 56.6 31.5 25.6 53.6 38.9 26.7 19.4 55.8 21.9 25.8 83.4 51.1 38.8 59.3 19.6 37.8 88.9 23.7 26.3 35.2 40.1 76.0 25.6 44.1 31.0 32.7 27.0 34.4 21.0 36.1 50.0 56.7 20.0 85.8 31.6 47.8 28.5 25.8 13.1 100.7 54.7 20.1 32.0 25.3 28.0 30.3 57.7 29.1 35.0 45.6 40.0 47.4 32.1 58.4 63.9 28.0 18.4 69.8 39.5 33.1 38.1 42.9 45.9 21.2 25.9 96.5 34.6 60.5 39.3 57.2 BTBD18 ENSG00000233436 "BTB domain containing 18" B2RXH4 11 57743514-57751781 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 3.1;testis: 2.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.7;Cone photoreceptor cells: 4.2;Rod photoreceptor cells: 1.6;Spermatocytes: 5.5;Spermatogonia: 3.9" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA049325 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 21: Non-specific - Transcription" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Nucleoplasm, Plasma membrane" Vesicles "HPA049325: AB_2680713" "unprognostic (6.68e-2)" "unprognostic (3.13e-2)" "unprognostic (3.43e-1)" "unprognostic (4.81e-2)" "unprognostic (1.75e-1)" "unprognostic (2.47e-2)" "unprognostic (8.69e-3)" "unprognostic (4.84e-3)" "unprognostic (1.77e-1)" "unprognostic (2.96e-1)" "unprognostic (7.17e-3)" "unprognostic (5.95e-3)" "unprognostic (1.42e-2)" "unprognostic (2.34e-2)" "unprognostic (3.15e-1)" "unprognostic (3.34e-1)" "unprognostic (2.88e-1)" 0.0 0.0 0.1 0.0 0.3 0.4 0.0 3.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.4 0.4 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.3 3.1 0.9 0.2 0.0 0.2 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.2 0.7 0.4 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.2 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 5.5 3.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BTN2A1 "BT2.1, BTF1, BTN2.1" ENSG00000112763 "Butyrophilin subfamily 2 member A1" Q7KYR7 6 26457904-26476621 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019208 Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA019208: AB_1845492" "unprognostic (1.86e-1)" "unprognostic (3.48e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-1)" "unprognostic (2.29e-1)" "unprognostic (6.17e-2)" "unprognostic (5.74e-3)" "unprognostic (1.22e-2)" "unprognostic (1.03e-1)" "unprognostic (3.26e-2)" "unprognostic (6.90e-3)" "unprognostic (5.14e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.97e-1)" "unprognostic (4.89e-2)" "unprognostic (7.92e-2)" "prognostic favorable (4.52e-5)" 16.1 17.3 10.8 11.4 10.7 16.8 13.3 19.9 13.1 15.5 11.4 17.7 9.8 16.7 8.3 8.9 16.1 10.2 16.0 11.1 15.2 13.6 9.1 18.4 13.9 12.1 13.2 15.2 8.9 4.8 11.9 19.0 13.7 13.3 11.0 4.5 9.5 14.4 11.7 8.2 15.0 16.9 12.0 25.7 12.2 11.7 13.5 10.6 10.5 10.1 11.4 17.3 13.3 12.2 16.4 14.5 28.9 18.3 12.7 10.2 1.4 36.1 30.1 42.3 38.7 13.5 11.0 13.3 47.3 24.5 54.9 7.0 22.1 8.9 40.2 18.4 21.6 7.9 15.3 16.0 19.9 11.8 21.2 13.9 8.2 47.1 15.2 25.1 15.3 25.4 13.5 20.6 35.7 6.7 19.9 18.2 9.7 4.8 11.9 17.0 27.3 13.6 16.5 7.3 28.9 16.4 11.2 14.8 26.4 17.8 4.3 9.9 21.3 32.1 16.6 28.1 40.8 16.1 40.4 11.1 12.8 22.0 52.1 43.6 9.0 30.2 11.1 5.2 9.8 8.6 9.3 12.4 8.4 6.2 8.6 11.0 51.7 9.9 8.8 8.9 16.0 7.2 10.8 10.7 19.9 13.1 11.1 15.2 12.1 13.2 13.7 12.0 13.5 12.2 21.2 16.0 14.7 7.5 20.0 8.0 8.0 8.5 9.1 8.0 11.8 10.9 17.6 7.2 11.7 9.2 6.2 6.1 35.4 16.0 3.9 10.9 3.2 18.1 17.7 22.1 9.0 4.6 8.9 12.8 11.2 14.7 18.8 20.8 24.6 13.3 21.8 6.2 11.6 3.3 10.2 14.8 12.2 17.9 16.7 6.2 12.8 18.4 10.6 10.3 21.9 6.0 25.7 10.6 7.8 16.4 10.2 12.8 18.9 13.1 11.4 4.7 26.9 2.3 39.5 12.4 24.4 8.7 12.9 7.3 8.1 11.8 25.0 14.9 12.9 17.9 BTRC "beta-TrCP1, betaTrCP, bTrCP, bTrCP1, FBXW1A, Fwd1" ENSG00000166167 "Beta-transducin repeat containing E3 ubiquitin protein ligase" Q9Y297 10 101354033-101557321 "Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 109.7;Excitatory neurons: 154.0;Inhibitory neurons: 144.4;Oligodendrocyte precursor cells: 183.5;Oligodendrocytes: 148.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031156, CAB032986" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "CAB032986: AB_2243598, HPA031156: AB_2673764" "unprognostic (1.43e-1)" "unprognostic (2.35e-2)" "unprognostic (8.88e-2)" "unprognostic (2.09e-1)" "unprognostic (3.55e-1)" "unprognostic (2.73e-1)" "unprognostic (2.41e-2)" "unprognostic (9.25e-2)" "unprognostic (3.22e-1)" "unprognostic (1.59e-2)" "unprognostic (8.80e-3)" "unprognostic (5.05e-1)" "unprognostic (2.81e-3)" "unprognostic (1.33e-1)" "unprognostic (2.95e-2)" "unprognostic (3.07e-2)" "unprognostic (2.23e-1)" 5.2 9.2 16.3 3.8 19.3 2.8 8.5 8.9 17.4 6.8 7.8 6.3 3.9 6.1 10.5 8.4 7.7 5.8 14.6 18.9 16.3 8.0 6.4 4.9 4.2 10.7 12.6 11.0 6.5 13.1 9.4 7.9 13.7 8.8 4.7 21.6 6.9 5.9 12.2 6.8 4.7 7.1 10.0 6.5 5.7 13.8 16.3 6.4 8.5 12.1 5.6 6.4 6.7 13.7 8.7 13.0 17.2 20.0 16.1 14.1 6.3 12.0 18.4 11.8 10.0 9.0 6.5 13.8 11.8 9.9 12.3 12.9 14.1 13.0 11.7 9.5 11.5 10.1 8.0 11.5 8.9 14.9 5.7 9.0 14.7 10.4 18.4 22.4 15.3 12.7 11.0 4.5 12.0 7.2 9.8 7.5 7.8 9.0 9.9 12.4 24.6 2.8 10.3 5.4 12.9 11.2 8.1 3.5 11.3 19.2 9.2 5.1 12.7 6.1 10.3 8.6 8.5 7.5 18.2 8.7 6.4 7.3 3.9 1.8 1.7 1.8 2.9 1.5 2.8 2.5 3.0 2.5 2.3 2.1 3.4 2.8 1.1 2.5 1.6 1.1 2.8 1.6 16.3 19.3 8.9 17.4 18.9 16.3 10.7 12.6 13.7 10.0 16.3 13.7 8.6 3.2 9.4 109.7 6.9 5.6 4.1 6.9 12.5 32.5 10.0 7.4 28.0 8.6 10.6 3.7 29.2 11.5 6.1 5.0 7.9 9.7 41.9 11.7 12.4 9.0 3.0 20.6 154.0 7.2 7.2 10.3 3.6 10.6 13.9 10.1 6.4 6.7 5.9 16.8 144.4 4.9 6.1 3.5 2.5 21.6 9.0 5.0 1.8 69.3 4.6 13.6 8.2 183.5 148.0 7.9 3.2 10.5 6.3 6.6 5.5 9.4 13.0 26.0 6.6 8.3 7.6 33.8 18.3 7.4 7.1 12.4 8.2 5.9 4.8 6.2 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 BZW2 "HSPC028, MST017, MSTP017" ENSG00000136261 "Basic leucine zipper and W2 domains 2" Q9Y6E2 7 16646131-16706523 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 265.5;skeletal muscle: 367.7;tongue: 258.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 278.2;Extravillous trophoblasts: 875.6;Syncytiotrophoblasts: 762.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022813, HPA026709" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Cytosol" "HPA022813: AB_1845511, HPA026709: AB_10600752" "unprognostic (2.27e-3)" "unprognostic (1.77e-3)" "unprognostic (5.91e-2)" "unprognostic (4.79e-3)" "unprognostic (2.80e-2)" "unprognostic (7.08e-3)" "prognostic unfavorable (7.86e-8)" "unprognostic (9.13e-3)" "unprognostic (8.49e-3)" "unprognostic (2.81e-2)" "unprognostic (1.83e-3)" "unprognostic (3.37e-2)" "prognostic unfavorable (6.01e-4)" "unprognostic (1.00e-1)" "unprognostic (1.66e-1)" "unprognostic (6.77e-2)" "unprognostic (1.25e-1)" 26.1 18.1 8.5 26.8 10.1 45.7 49.7 6.9 14.3 19.1 9.7 51.2 28.9 18.4 9.9 42.6 20.2 17.2 265.5 10.2 6.3 37.8 18.4 20.0 30.0 5.2 6.3 16.0 30.0 6.7 10.4 80.4 6.5 19.3 56.8 88.0 23.8 34.3 367.7 55.5 30.0 39.0 5.6 16.5 50.2 11.6 6.9 33.0 36.5 258.9 38.4 59.5 26.2 8.8 91.7 81.3 138.2 201.7 67.5 118.3 125.7 126.0 156.3 117.6 124.9 201.8 129.7 208.0 143.7 96.9 87.6 181.6 164.8 141.5 152.0 27.8 99.8 129.6 84.4 117.0 70.5 180.3 79.1 90.6 74.6 104.0 187.7 92.4 171.6 149.7 251.9 43.5 96.9 105.0 90.0 210.4 143.9 259.5 174.1 111.0 91.2 216.6 113.4 152.6 179.9 106.8 50.8 419.9 67.7 156.7 187.8 149.5 97.6 93.1 119.1 141.5 136.3 89.5 92.8 288.1 45.5 220.6 340.3 2.6 46.0 5.0 27.3 55.2 44.6 44.6 39.8 36.9 98.8 42.9 56.8 47.1 2.1 56.8 41.6 38.5 31.8 44.0 8.5 10.1 6.9 14.3 10.2 6.3 5.2 6.3 6.5 5.6 6.9 8.8 32.8 22.4 60.5 3.9 30.0 57.6 69.9 60.5 82.6 55.9 52.3 57.0 278.2 17.2 53.9 47.8 64.6 214.3 26.8 42.4 58.7 47.5 9.8 31.9 43.2 42.9 30.5 63.5 48.6 65.6 875.6 43.5 110.1 40.6 21.0 33.3 8.9 13.7 65.0 6.7 32.0 49.5 61.1 33.4 46.0 6.4 12.2 30.7 24.9 12.2 47.5 19.7 19.6 19.1 17.9 47.0 42.9 9.8 31.9 52.0 19.2 20.8 32.6 106.4 6.6 30.2 54.2 11.3 4.1 99.6 51.6 762.9 29.3 52.6 90.6 79.0 C10orf90 "bA422P15.2, FATS, FLJ32938" ENSG00000154493 "Chromosome 10 open reading frame 90" Q96M02 10 126424997-126798708 "Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "brain: 112.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 819.4" "Cancer enriched" "Detected in some" 5 "melanoma: 4.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-MEL-30: 118.8;U-2197: 36.1;U-266/84: 27.2;U-87 MG: 37.0;WM-115: 29.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038648, HPA075229" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038648: AB_10672721, HPA075229: " "unprognostic (1.21e-2)" "unprognostic (3.34e-1)" "unprognostic (7.50e-2)" "unprognostic (2.05e-2)" "unprognostic (1.66e-1)" "unprognostic (9.30e-2)" "unprognostic (1.98e-3)" "unprognostic (5.06e-2)" "unprognostic (9.34e-3)" "unprognostic (3.73e-2)" "unprognostic (9.52e-2)" "unprognostic (1.22e-1)" "unprognostic (5.06e-11)" "unprognostic (2.69e-3)" "unprognostic (9.91e-3)" "unprognostic (1.26e-1)" "unprognostic (2.88e-1)" 0.7 0.0 30.4 0.1 74.4 0.0 4.7 41.9 47.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 29.9 37.4 0.3 0.1 0.0 0.0 60.4 53.8 0.1 0.2 0.0 0.3 0.3 57.0 0.0 0.1 0.0 10.6 0.0 0.1 1.1 0.1 0.0 29.8 0.0 0.0 6.5 68.0 1.1 0.3 0.4 0.7 0.0 0.0 112.1 0.3 0.1 0.0 0.0 0.8 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 2.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 2.3 0.0 1.6 0.0 0.9 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 2.6 0.0 0.0 0.0 0.0 118.8 0.0 0.0 0.2 0.0 4.7 0.0 36.1 0.7 0.0 27.2 0.0 37.0 0.0 29.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.4 74.4 41.9 47.7 29.9 37.4 60.4 53.8 57.0 29.8 68.0 112.1 0.2 0.0 0.0 24.5 0.1 0.0 0.0 0.0 0.0 0.0 3.0 2.7 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 120.5 0.0 0.0 0.1 0.0 0.0 2.2 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.0 142.7 0.3 0.0 0.0 3.7 0.0 0.0 0.0 181.0 819.4 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 1.3 0.5 0.0 0.0 4.2 0.1 0.0 0.0 0.0 C11orf42 MGC34805 ENSG00000180878 "Chromosome 11 open reading frame 42" Q8N5U0 11 6205557-6211135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "testis: 25.4" "Cell type enriched" "Detected in some" 5 "Late spermatids: 818.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 1.3;HeLa: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA063404 Enhanced Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nuclear membrane, Vesicles" "HPA063404: AB_2685006" "unprognostic (4.79e-2)" "unprognostic (1.83e-1)" "unprognostic (3.18e-1)" "unprognostic (2.56e-1)" "unprognostic (1.39e-3)" "unprognostic (3.49e-3)" "unprognostic (2.05e-1)" "unprognostic (5.39e-2)" "unprognostic (1.26e-1)" "unprognostic (3.50e-2)" "unprognostic (9.30e-2)" "unprognostic (6.47e-3)" "unprognostic (7.02e-2)" "unprognostic (1.09e-1)" "unprognostic (1.56e-1)" "unprognostic (2.07e-2)" "unprognostic (4.74e-2)" 0.0 0.1 0.5 0.2 0.5 0.1 0.1 1.4 0.7 0.1 0.0 0.3 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.4 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.1 0.0 1.4 0.2 0.0 0.1 1.5 0.7 0.0 0.0 0.2 0.3 25.4 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.1 0.8 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.8 0.2 0.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.2 1.3 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.3 0.1 0.0 0.2 0.3 0.1 0.4 0.1 0.4 0.2 0.3 0.0 0.0 0.1 0.4 0.1 0.0 0.3 0.1 0.1 0.1 0.3 0.1 0.3 0.1 0.6 0.1 0.1 0.3 0.1 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 1.4 0.7 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 146.5 0.0 0.0 0.1 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 818.5 1.5 0.2 0.0 1.0 0.0 0.0 0.0 2.0 2.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C11orf52 "FLJ25219, MGC14839" ENSG00000149300 "Chromosome 11 open reading frame 52" Q96A22 11 111918032-111926871 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.8;Breast glandular cells: 3.3;Cholangiocytes: 2.8;Endometrial ciliated cells: 3.1;Gastric mucus-secreting cells: 4.1;Respiratory ciliated cells: 6.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.7;CAPAN-2: 23.5;Hep G2: 18.2;MCF7: 17.6;RPTEC TERT1: 27.1;SK-BR-3: 22.9;T-47d: 76.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038387, HPA038388" Uncertain Enhanced "Cell Junctions" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions" "HPA038387: AB_10670167, HPA038388: AB_2675987" "unprognostic (1.30e-2)" "unprognostic (1.13e-1)" "unprognostic (5.84e-4)" "unprognostic (1.48e-4)" "unprognostic (2.57e-1)" "unprognostic (8.04e-2)" "unprognostic (6.77e-2)" "unprognostic (2.07e-2)" "unprognostic (2.26e-1)" "unprognostic (2.77e-1)" "unprognostic (3.80e-1)" "unprognostic (5.38e-4)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "unprognostic (3.03e-1)" 3.3 0.7 1.0 0.4 0.9 0.0 25.9 4.1 1.3 3.8 2.2 5.2 10.4 2.3 23.7 6.4 17.7 12.3 3.2 0.9 0.9 43.9 22.8 9.7 0.1 1.1 1.0 1.5 25.8 30.8 16.4 10.1 1.7 15.4 6.2 0.1 26.8 10.2 9.3 9.7 9.2 0.8 1.1 0.9 20.9 1.0 1.1 1.0 20.1 8.3 1.3 4.6 3.2 1.5 4.3 0.0 0.0 0.0 2.9 0.4 17.7 1.0 0.8 0.1 0.0 6.8 23.5 0.0 10.6 2.3 0.0 5.4 0.0 1.4 0.1 0.0 0.7 0.0 0.5 18.2 0.0 0.0 0.0 0.3 5.2 0.0 0.2 0.2 1.0 0.0 0.0 0.0 1.5 17.6 0.0 0.2 0.1 12.5 1.8 0.0 1.5 0.0 27.1 15.6 1.2 0.0 0.0 22.9 0.0 2.4 76.5 1.6 2.0 0.5 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 4.1 1.3 0.9 0.9 1.1 1.0 1.7 1.1 1.1 1.5 0.0 6.4 2.8 0.0 0.0 0.1 1.6 0.2 1.2 0.0 3.3 0.9 0.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 1.3 0.0 3.1 0.2 0.2 0.0 0.0 0.0 1.0 0.3 0.5 4.1 1.9 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 1.9 1.3 6.7 0.0 0.0 0.3 0.3 0.1 0.1 0.6 0.3 1.4 0.0 0.2 0.2 0.7 C12orf73 "BRAWNIN, DKFZp547P055, FLJ13975" ENSG00000204954 "Chromosome 12 open reading frame 73" Q69YU5 12 103940763-103965708 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 42.5" "Cell type enhanced" "Detected in many" "Early spermatids: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038883 Uncertain Approved "Plasma membrane,Centrosome,Mitochondria" "Intracellular and membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Centrosome, Mitochondria" "Plasma membrane" "HPA038883: AB_10794735" "unprognostic (9.24e-2)" "unprognostic (3.26e-3)" "unprognostic (3.66e-3)" "unprognostic (7.20e-2)" "unprognostic (3.28e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (6.98e-4)" "unprognostic (8.96e-2)" "unprognostic (1.86e-2)" "unprognostic (3.79e-2)" "unprognostic (3.03e-3)" "unprognostic (2.07e-1)" "unprognostic (1.33e-2)" "unprognostic (1.13e-1)" "unprognostic (1.40e-2)" "unprognostic (6.27e-2)" "prognostic favorable (1.61e-4)" 6.0 11.4 15.6 7.7 15.4 4.4 7.9 17.1 16.1 8.5 13.3 7.2 7.0 8.2 10.3 6.4 7.3 4.6 12.3 15.5 16.7 10.3 8.3 5.8 9.2 14.7 15.0 10.1 7.7 10.0 10.8 6.1 15.2 8.7 7.6 13.2 7.2 7.3 42.5 8.3 6.8 6.5 14.4 6.9 8.9 10.9 15.3 8.3 12.9 27.6 8.9 7.3 6.9 17.3 11.8 21.2 31.8 19.4 8.9 11.6 20.7 12.6 7.4 13.4 10.8 23.2 9.9 13.7 15.9 7.5 11.7 18.3 19.1 15.6 10.1 19.7 38.4 20.9 32.9 29.1 13.1 30.8 18.2 10.3 17.6 6.9 11.9 32.5 12.5 39.5 27.0 9.2 12.5 13.2 34.5 46.1 15.6 11.0 35.9 19.7 11.9 13.7 17.8 16.6 51.8 18.5 13.0 21.9 29.7 14.1 36.4 16.7 6.5 16.4 9.3 12.4 12.8 24.5 40.6 28.8 22.4 17.4 14.5 10.1 5.6 10.6 11.7 5.0 11.4 14.6 10.6 11.1 8.6 11.3 15.7 14.8 1.7 14.5 4.5 13.3 17.0 4.2 15.6 15.4 17.1 16.1 15.5 16.7 14.7 15.0 15.2 14.4 15.3 17.3 6.8 6.4 6.8 7.5 7.8 6.0 9.4 16.3 18.8 16.3 9.0 11.0 16.5 7.2 10.0 9.2 0.0 11.6 8.6 7.1 27.4 20.3 87.1 8.7 10.3 8.3 11.4 18.5 5.0 12.1 11.7 7.9 15.3 9.1 9.5 13.8 8.9 15.5 17.5 8.4 6.0 13.2 20.3 7.9 5.1 36.6 8.7 8.7 1.8 2.8 12.4 17.1 22.6 7.5 9.0 19.9 5.6 8.6 13.7 13.7 16.0 25.9 10.9 15.2 6.6 5.6 11.7 31.1 25.6 16.0 5.3 8.9 8.8 6.4 12.3 8.6 C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073634 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 77.2;choroid plexus: 44.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 60.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA039713 Uncertain Approved "Plasma membrane,Actin filaments" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 51: Myeloid cells - Hemostasis" "Actin filaments" "Plasma membrane" "HPA039713: AB_2676640" "unprognostic (9.20e-2)" "unprognostic (3.31e-2)" "unprognostic (2.35e-3)" "unprognostic (9.54e-2)" "unprognostic (3.50e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "prognostic favorable (6.44e-5)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" 4.0 5.0 58.2 5.4 61.5 2.4 7.4 67.2 76.0 6.8 44.0 6.2 3.5 5.6 9.9 3.9 10.3 3.7 4.0 59.5 61.6 8.4 10.1 8.0 8.5 64.9 63.6 8.4 6.4 3.9 10.2 8.0 67.3 6.7 4.7 16.6 5.0 5.1 6.7 4.6 5.7 3.4 60.0 9.2 4.6 8.3 61.3 7.1 9.6 4.1 6.1 5.5 5.4 77.2 3.8 7.5 10.7 8.8 5.2 12.2 10.9 3.4 3.0 7.3 5.0 4.8 4.3 8.1 4.6 1.8 5.0 8.8 4.2 5.4 5.0 9.8 9.9 8.5 7.2 13.3 7.2 13.6 16.2 13.7 14.9 4.7 11.3 19.7 10.7 13.4 13.0 3.0 5.4 4.1 4.3 25.2 9.4 5.1 6.1 10.5 7.0 12.5 11.2 4.1 26.4 12.5 5.3 2.8 11.1 13.3 8.4 6.2 6.2 3.5 4.9 3.4 1.5 8.4 12.8 4.4 8.2 6.3 3.5 60.0 10.2 11.0 6.4 7.8 9.2 18.6 12.7 7.1 10.9 11.6 17.4 10.2 5.8 18.8 5.2 9.7 12.8 12.0 58.2 61.5 67.2 76.0 59.5 61.6 64.9 63.6 67.3 60.0 61.3 77.2 22.5 32.1 17.0 13.4 15.2 7.9 16.2 18.7 13.6 26.4 24.9 39.8 7.1 18.6 10.5 16.5 2.1 30.2 13.3 6.4 35.2 11.6 31.0 42.3 18.7 18.3 6.1 14.5 32.0 15.1 10.5 17.7 6.6 17.4 5.1 22.8 21.8 22.4 26.4 32.0 28.5 10.7 16.2 24.2 13.1 13.5 26.1 35.9 19.6 15.0 25.3 39.4 24.7 53.3 174.6 11.8 7.5 33.8 10.2 11.7 13.3 38.6 33.9 20.9 6.6 16.4 16.5 25.2 11.3 9.0 8.5 12.0 21.8 15.4 9.5 9.8 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C16orf74 MGC17624 ENSG00000154102 "Chromosome 16 open reading frame 74" Q96GX8 16 85690084-85751129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 47.4;Basal prostatic cells: 56.7;Bipolar cells: 55.8;Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 87.8;Syncytiotrophoblasts: 74.3;Urothelial cells: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 96.1;hTCEpi: 80.8;T-47d: 84.5" HPA049367 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Plasma membrane" Centrosome "HPA049367: AB_2680730" "unprognostic (1.16e-1)" "unprognostic (2.21e-2)" "unprognostic (6.74e-3)" "unprognostic (2.15e-3)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.08e-3)" "unprognostic (4.22e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.40e-1)" "unprognostic (1.76e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-1)" "unprognostic (2.15e-2)" "unprognostic (9.07e-3)" 3.6 0.7 8.4 4.3 8.5 8.9 6.5 6.8 12.0 9.5 7.8 3.1 1.4 1.5 2.0 9.4 1.5 2.2 2.2 12.2 7.4 2.5 1.1 2.2 8.4 7.5 7.4 0.8 1.8 7.5 1.3 6.7 7.0 9.2 1.1 27.7 4.2 7.3 0.5 9.0 5.6 0.9 6.7 16.0 2.9 2.1 7.6 1.4 5.0 0.3 6.4 17.2 14.5 7.4 35.3 11.5 0.4 4.7 5.1 5.6 14.1 4.2 5.6 13.1 3.7 8.9 32.1 0.3 47.2 3.3 5.5 49.4 2.0 96.1 7.4 0.0 7.6 0.0 5.3 0.9 13.9 1.0 0.0 12.2 80.8 12.6 54.7 9.8 43.4 5.8 0.0 0.2 0.4 29.6 0.0 54.0 2.9 37.7 32.6 1.4 0.0 2.8 0.1 39.5 10.7 2.8 17.5 8.9 9.1 3.6 84.5 14.9 44.8 8.4 22.0 3.8 12.7 11.7 9.3 40.0 0.0 12.6 1.7 0.1 16.8 21.8 1.3 6.3 4.4 46.7 8.8 7.0 18.3 49.4 14.5 9.3 6.6 7.8 2.0 0.3 18.0 10.8 8.4 8.5 6.8 12.0 12.2 7.4 7.5 7.4 7.0 6.7 7.6 7.4 10.1 3.2 1.1 6.5 47.4 9.3 56.7 23.8 8.0 55.8 19.0 20.3 1.8 1.5 9.8 1.8 58.4 45.8 3.4 0.1 3.9 3.0 1.7 4.4 4.6 7.2 0.0 0.8 0.4 1.1 19.7 5.7 1.5 4.1 0.0 0.5 2.5 0.0 5.0 15.2 0.4 0.0 8.2 1.2 2.9 0.4 3.4 2.5 19.6 1.0 5.2 18.8 4.1 1.5 0.8 3.2 0.0 3.4 44.2 36.5 0.0 2.4 3.9 87.8 0.0 0.3 2.5 0.9 8.4 8.5 7.0 74.3 3.7 1.5 0.2 55.7 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.2;Late spermatids: 76.3;Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" 16.4 18.2 15.2 12.8 15.7 71.9 20.5 18.6 19.7 13.6 14.2 15.1 16.2 15.3 18.4 14.7 14.9 12.3 18.3 15.4 15.2 15.1 16.9 12.2 21.8 15.0 15.0 17.0 23.2 17.9 12.9 14.6 15.0 14.4 13.1 19.2 19.3 12.9 34.1 16.3 15.2 13.0 15.6 18.1 19.8 35.8 15.4 21.9 14.0 26.4 18.8 16.3 12.3 16.5 24.9 17.2 35.3 27.0 25.4 36.2 25.9 34.3 34.9 42.3 44.7 15.8 17.8 22.4 33.7 27.4 26.9 26.2 28.2 28.8 45.7 33.4 30.4 22.5 21.2 35.5 35.3 65.4 26.3 37.9 46.7 38.2 39.3 36.8 37.0 30.6 39.7 34.0 29.4 29.5 42.4 48.0 30.4 11.6 18.9 28.0 30.7 43.0 29.2 29.5 25.5 36.0 25.4 18.8 58.3 32.7 28.2 31.2 24.3 43.3 19.1 15.8 31.0 43.2 41.4 46.0 21.4 37.3 22.1 97.5 28.8 34.2 24.5 30.7 24.2 34.7 25.9 23.2 27.1 30.9 19.8 25.9 28.0 28.8 30.0 26.6 41.5 19.8 15.2 15.7 18.6 19.7 15.4 15.2 15.0 15.0 15.0 15.6 15.4 16.5 9.6 19.2 6.1 3.9 13.7 11.9 8.9 17.4 18.2 9.6 13.1 16.5 12.7 10.0 12.1 1.8 6.2 19.0 23.0 10.4 11.7 20.2 145.2 13.7 14.7 10.8 7.2 12.4 5.5 28.8 32.0 12.4 8.6 14.4 14.0 12.9 10.0 9.6 21.3 8.4 6.0 12.9 16.2 20.1 10.3 76.3 22.4 14.4 12.4 5.6 24.4 13.1 20.6 4.5 5.1 20.0 14.0 17.0 13.5 11.7 17.8 20.1 5.1 12.1 0.0 14.1 11.3 124.0 35.9 12.8 12.4 13.1 13.6 17.3 15.9 9.3 C19orf33 "H2RSP, IMUP, IMUP-1, IMUP-2" ENSG00000167644 "Chromosome 19 open reading frame 33" Q9GZP8 19 38304164-38305006 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 515.3;skin 1: 331.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2060.3;Pancreatic endocrine cells: 2590.4;Paneth cells: 1697.3;Proximal enterocytes: 1756.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 10 "myeloid DC: 22.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 22.2" "Cell line enhanced" "Detected in many" "A-431: 745.5;A549: 1228.0;CAPAN-2: 767.1;HBEC3-KT: 744.6;hTCEpi: 799.2;OE19: 678.3;PC-3: 659.8" "Not detected" "Not detected" "HPA054406, HPA059696" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 460000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "HPA054406: AB_2682478, HPA059696: AB_2684105" "unprognostic (9.31e-2)" "unprognostic (2.06e-1)" "unprognostic (4.34e-2)" "unprognostic (1.44e-2)" "unprognostic (3.92e-3)" "unprognostic (2.37e-2)" "unprognostic (9.49e-2)" "prognostic unfavorable (5.42e-4)" "unprognostic (2.09e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (5.05e-4)" "unprognostic (6.92e-2)" "unprognostic (5.50e-2)" "unprognostic (4.82e-2)" "unprognostic (1.61e-1)" "unprognostic (3.63e-2)" "unprognostic (6.01e-2)" 43.1 5.0 2.8 17.6 3.1 3.6 25.5 2.9 4.4 82.4 2.9 187.5 186.7 6.1 0.6 515.3 91.5 49.5 32.9 2.3 2.6 28.2 1.3 91.3 0.9 3.1 3.0 4.6 8.9 0.5 12.7 7.9 3.4 26.2 104.1 0.1 123.3 18.3 3.9 331.1 189.5 4.0 2.5 10.7 151.5 1.5 3.8 4.1 18.9 4.3 30.8 102.2 224.3 2.5 745.5 1228.0 0.0 0.6 0.0 0.0 1.2 1.0 0.0 0.0 0.0 77.1 767.1 0.0 394.2 0.0 0.7 300.1 0.0 744.6 0.0 0.4 0.5 0.4 244.2 20.0 5.4 0.0 0.2 0.0 799.2 0.3 493.3 3.3 10.2 0.9 0.4 0.5 0.8 220.4 0.1 1.9 0.4 678.3 659.8 0.2 0.2 2.8 469.5 255.2 0.8 0.8 416.6 340.8 0.8 1.6 103.7 2.3 141.6 0.5 201.9 0.7 2.8 0.7 2.4 3.7 0.1 0.2 0.2 2.1 0.6 2.2 0.2 0.0 0.4 0.1 0.5 0.1 22.2 1.4 0.7 0.3 1.0 0.4 0.1 1.8 0.0 18.2 2.8 3.1 2.9 4.4 2.3 2.6 3.1 3.0 3.4 2.5 3.8 2.5 29.1 535.2 172.9 0.0 5.4 225.3 28.4 508.7 436.5 0.0 32.5 25.5 2.4 267.4 418.0 55.2 0.0 8.6 1.7 2060.3 1.9 207.7 0.7 144.3 26.0 18.4 76.1 3.6 0.1 753.8 1.3 44.7 353.7 273.2 38.2 3.7 3.6 0.4 1.3 0.0 0.0 842.0 99.7 1.4 15.1 5.1 4.1 32.9 1.8 0.0 4.9 0.0 0.0 0.0 0.0 2590.4 1697.3 0.0 5.7 35.7 1756.4 51.7 212.5 0.0 0.0 0.4 14.3 1.8 1.9 629.0 348.4 3.1 7.9 0.0 691.9 188.4 C19orf38 HIDE1 ENSG00000214212 "Chromosome 19 open reading frame 38" A8MVS5 19 10836575-10869790 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "bone marrow: 98.0" "Cell type enhanced" "Detected in many" "Kupffer cells: 90.1;Langerhans cells: 33.4;Macrophages: 59.2;monocytes: 86.7;Plasma cells: 24.7;Spermatocytes: 28.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 20 "classical monocyte: 282.3;eosinophil: 169.4;intermediate monocyte: 312.5;myeloid DC: 162.2;neutrophil: 230.1;non-classical monocyte: 392.8" "Group enriched" "Detected in all" 20 "dendritic cells: 162.2;granulocytes: 230.1;monocytes: 392.8" "Cell line enriched" "Detected in some" 4 "U-937: 50.9" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA012150, HPA055027" Uncertain "Golgi apparatus,Plasma membrane,Cytosol" No NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Golgi apparatus, Plasma membrane" "HPA012150: AB_10603448, HPA055027: " "unprognostic (6.65e-3)" "prognostic favorable (2.43e-4)" "unprognostic (6.44e-4)" "unprognostic (6.98e-2)" "unprognostic (2.19e-1)" "unprognostic (5.31e-3)" "unprognostic (3.56e-1)" "unprognostic (8.27e-2)" "unprognostic (5.60e-2)" "unprognostic (6.02e-2)" "unprognostic (9.74e-2)" "unprognostic (3.43e-2)" "prognostic unfavorable (1.75e-7)" "unprognostic (2.31e-1)" "unprognostic (4.00e-2)" "unprognostic (1.03e-2)" "unprognostic (2.11e-2)" 3.6 1.0 3.5 11.2 3.9 98.0 1.2 4.2 4.5 2.1 3.5 1.8 1.7 1.0 2.7 1.0 2.3 2.9 0.9 3.4 4.1 1.2 3.2 6.1 5.2 5.2 4.3 2.0 1.7 0.4 0.8 1.8 5.2 1.3 1.2 0.7 0.9 0.9 2.7 0.5 2.3 3.4 4.6 21.7 1.6 11.1 4.0 3.2 0.5 1.5 3.0 4.6 1.6 6.0 2.4 0.1 0.2 0.4 2.2 1.2 0.2 0.4 0.1 0.4 0.9 0.2 0.4 5.9 0.5 0.0 0.2 0.2 0.3 0.3 0.3 2.7 0.6 0.3 0.0 0.0 1.6 3.9 0.6 6.0 0.7 1.0 0.3 0.1 0.1 0.6 0.3 12.2 0.2 2.2 0.2 9.3 0.5 0.4 0.4 4.5 0.0 3.1 0.0 0.2 0.3 0.1 1.2 0.0 0.9 0.1 0.2 8.7 0.0 0.1 0.0 1.1 0.1 7.3 3.7 1.7 0.0 50.9 0.0 7.8 282.3 169.4 0.6 312.5 1.6 13.0 0.8 0.8 162.2 8.5 4.9 1.5 230.1 8.0 392.8 3.6 2.3 157.7 3.5 3.9 4.2 4.5 3.4 4.1 5.2 4.3 5.2 4.6 4.0 6.0 0.3 0.0 1.8 1.6 10.6 0.8 0.4 2.1 1.2 0.1 0.6 0.5 1.1 0.0 1.7 1.8 2.1 1.0 0.7 0.3 0.0 0.1 3.7 0.9 0.3 1.1 0.0 4.8 0.9 1.3 0.9 1.6 4.1 1.0 2.5 0.3 0.4 1.1 22.3 0.0 0.9 0.6 2.0 90.1 33.4 6.1 0.9 59.2 1.8 0.0 86.7 3.1 4.1 0.0 3.1 0.1 3.5 0.7 24.7 0.3 0.2 0.7 5.1 1.1 6.6 0.5 0.6 28.5 19.2 0.3 0.9 0.7 2.1 0.1 0.6 0.6 C19orf71 LOC100128569 ENSG00000183397 "Chromosome 19 open reading frame 71" A6NCJ1 19 3539154-3544030 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 53.7" "Group enriched" "Detected in some" 69 "Early spermatids: 566.4;Late spermatids: 357.0" "Cancer enriched" "Detected in all" 5 "melanoma: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HeLa: 92.7;SK-MEL-30: 48.2;WM-115: 170.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA048654 Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Endoplasmic reticulum" "HPA048654: AB_2680480" "unprognostic (1.06e-1)" "unprognostic (1.21e-1)" "unprognostic (7.04e-3)" "unprognostic (7.37e-2)" "unprognostic (4.74e-2)" "prognostic favorable (2.35e-4)" "unprognostic (4.21e-1)" "unprognostic (2.00e-1)" "unprognostic (7.23e-2)" "unprognostic (3.13e-2)" "prognostic favorable (2.03e-5)" "unprognostic (6.19e-2)" "prognostic favorable (2.02e-5)" "unprognostic (5.52e-3)" "unprognostic (1.02e-1)" "unprognostic (3.84e-2)" "unprognostic (1.97e-3)" 2.6 4.5 3.7 8.1 3.5 10.5 2.2 15.0 5.6 3.4 0.0 2.7 8.5 4.9 0.8 3.5 4.5 3.8 2.5 4.4 5.6 6.3 3.5 4.4 9.5 4.6 3.1 4.7 7.6 0.7 7.5 3.2 3.8 4.1 0.6 3.3 12.3 2.3 2.5 13.0 7.3 0.9 1.4 9.8 6.0 53.7 4.6 1.9 11.0 0.5 1.2 2.6 2.5 10.9 15.9 12.8 4.1 5.5 0.1 0.1 8.3 9.8 0.0 0.0 0.0 8.1 4.7 2.8 7.2 0.1 20.8 13.8 0.1 0.7 0.0 16.0 7.5 2.1 92.7 2.4 0.0 2.1 9.7 0.1 0.2 0.3 0.1 4.5 0.1 7.3 11.1 13.9 0.0 11.1 3.5 5.2 3.5 0.5 3.9 5.3 6.1 14.9 0.0 6.2 9.7 8.9 17.0 8.5 48.2 1.9 9.6 5.2 13.2 7.6 9.9 23.2 9.3 11.0 3.1 4.1 22.7 9.4 170.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 3.5 15.0 5.6 4.4 5.6 4.6 3.1 3.8 1.4 4.6 10.9 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 566.4 0.3 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 357.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 3.8 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 2.7 1.6 0.0 0.0 0.1 0.1 0.2 0.0 0.1 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C1orf189 ENSG00000163263 "Chromosome 1 open reading frame 189" Q5VU69 1 154199085-154206333 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "fallopian tube: 30.5;testis: 19.7" "Cell type enhanced" "Detected in some" "Early spermatids: 88.7;Endometrial ciliated cells: 30.7;Late spermatids: 19.6;Respiratory ciliated cells: 25.1" "Cancer enhanced" "Detected in many" "endometrial cancer: 5.2" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045779 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Golgi apparatus, Plasma membrane" "HPA045779: AB_2679448" "unprognostic (8.23e-3)" "unprognostic (5.55e-3)" "unprognostic (2.39e-2)" "unprognostic (2.01e-3)" "unprognostic (2.50e-3)" "unprognostic (2.02e-1)" "unprognostic (8.15e-2)" "unprognostic (1.62e-1)" "unprognostic (2.24e-2)" "unprognostic (8.78e-3)" "unprognostic (1.36e-2)" "unprognostic (7.40e-2)" "unprognostic (3.20e-2)" "unprognostic (3.75e-2)" "unprognostic (2.06e-1)" "unprognostic (9.79e-2)" "unprognostic (3.05e-2)" 0.1 0.0 0.2 0.1 0.3 0.5 0.1 0.4 0.4 1.6 0.6 0.0 0.0 0.5 0.3 0.1 30.5 0.0 0.1 0.3 0.4 0.1 0.3 1.8 0.1 1.6 3.4 0.1 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.1 0.0 0.9 0.0 0.1 19.7 0.5 0.0 0.0 0.5 0.2 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.4 0.2 0.3 0.1 0.0 0.0 0.0 0.2 0.3 0.0 0.2 0.4 0.2 0.4 0.3 0.2 0.1 0.2 0.3 0.2 0.1 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.5 0.1 0.1 0.5 0.2 0.5 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.3 0.0 0.4 0.2 0.2 0.5 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.4 0.4 0.3 0.4 1.6 3.4 1.2 0.9 0.5 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.7 30.7 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 19.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.2 25.1 0.0 0.0 0.0 0.0 7.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 C1orf35 "MGC4174, MMTAG2" ENSG00000143793 "Chromosome 1 open reading frame 35" Q9BU76 1 228100726-228105411 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046175 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nuclear speckles, Plasma membrane" Cytosol "HPA046175: AB_10959459" "unprognostic (1.12e-1)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.71e-4)" "unprognostic (6.41e-2)" "unprognostic (1.21e-1)" "unprognostic (2.64e-2)" "unprognostic (5.44e-3)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "prognostic favorable (7.38e-4)" "unprognostic (6.12e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.70e-1)" "unprognostic (8.58e-2)" "unprognostic (5.56e-2)" "unprognostic (3.70e-2)" 11.3 12.5 20.6 6.3 20.4 14.3 11.7 19.5 24.4 15.5 18.2 13.4 7.9 13.4 5.5 18.8 13.0 4.0 9.4 20.5 20.3 11.2 11.6 8.6 9.0 20.8 19.7 16.1 12.9 7.4 9.9 7.1 20.6 14.2 3.9 2.7 12.5 8.5 9.6 19.6 10.5 5.0 19.2 10.8 12.3 7.5 20.3 9.2 12.1 3.5 7.3 14.4 14.7 21.0 22.2 24.3 17.0 10.9 8.2 8.3 40.0 16.8 7.4 14.6 10.9 24.1 22.2 22.7 35.6 6.6 10.3 25.4 16.0 16.6 5.3 24.6 76.7 13.9 20.1 23.1 13.3 32.0 16.7 7.6 19.5 14.3 13.1 9.2 16.1 26.1 35.2 13.3 10.7 27.8 42.0 44.4 34.4 28.5 55.6 32.1 24.2 36.4 13.6 18.2 28.1 27.2 16.0 29.4 23.3 4.5 31.0 29.2 15.1 11.8 18.1 32.7 37.2 23.9 12.7 21.6 14.2 18.3 19.2 14.9 29.0 43.3 28.2 35.9 35.2 37.2 31.1 30.7 37.6 29.9 36.1 30.2 4.7 35.9 34.9 49.3 34.7 17.5 20.6 20.4 19.5 24.4 20.5 20.3 20.8 19.7 20.6 19.2 20.3 21.0 37.7 22.4 22.4 10.4 29.8 66.8 35.5 58.5 47.3 51.4 41.1 50.9 18.1 28.6 31.0 38.6 18.8 76.2 49.8 61.6 45.0 38.0 4.4 28.2 31.7 33.9 26.3 57.4 12.9 39.5 59.3 34.3 25.0 43.7 24.7 36.9 32.2 24.4 40.4 47.1 10.1 58.8 54.9 24.2 72.7 5.5 51.3 29.8 32.0 2.8 32.4 42.5 30.9 9.5 14.3 37.5 43.5 46.6 28.1 37.4 47.8 38.3 25.1 54.5 65.7 31.6 44.7 44.0 50.0 54.1 80.6 28.3 47.2 28.0 56.6 25.8 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 78.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HaCaT: 1.8" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" 0.4 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 678.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 78.3 0.0 0.1 0.0 0.0 0.0 C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 14.9;Glandular and luminal cells: 28.4;Squamous epithelial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" 0.6 0.9 0.7 2.4 0.7 1.1 2.2 1.8 0.7 0.9 0.2 1.6 1.3 0.8 2.0 4.0 1.1 0.9 1.5 0.7 0.9 1.9 1.7 0.9 4.3 0.8 0.8 0.9 0.8 1.2 0.8 1.1 0.8 1.6 2.0 0.9 1.9 0.9 1.0 6.7 2.8 0.6 0.7 4.2 1.7 1.3 1.1 2.1 1.2 0.9 2.4 1.9 1.7 0.8 4.7 2.4 1.5 0.8 2.0 2.3 3.5 2.6 3.4 3.1 3.2 4.9 3.5 4.9 1.5 1.7 1.9 9.3 0.9 7.6 3.6 4.9 3.1 3.2 1.7 0.4 2.8 4.6 1.4 1.4 6.6 3.9 6.3 2.6 1.8 6.6 6.5 3.5 2.7 2.4 3.9 4.7 6.4 3.2 4.1 4.0 7.2 6.9 2.7 4.0 6.0 6.5 3.5 2.7 4.0 3.4 4.2 2.4 1.7 2.6 3.1 2.7 4.2 3.2 3.4 5.4 2.3 3.7 3.8 4.7 0.8 0.7 1.3 0.9 0.9 1.8 0.6 1.0 1.6 3.7 1.1 1.2 0.5 1.5 0.5 2.7 0.6 0.9 0.7 0.7 1.8 0.7 0.7 0.9 0.8 0.8 0.8 0.7 1.1 0.8 0.6 3.2 2.2 0.0 1.1 2.2 6.1 4.6 6.8 1.6 3.7 2.8 2.0 0.0 1.8 0.0 0.0 3.9 1.5 3.5 7.9 1.9 0.1 14.9 1.8 0.8 3.6 2.1 0.5 2.0 5.0 0.9 2.6 28.4 1.3 2.2 1.4 2.3 2.8 1.7 0.6 5.9 0.0 1.3 0.3 0.6 2.5 1.6 0.0 1.0 1.3 2.2 0.0 0.0 0.3 4.1 3.5 0.0 0.6 5.1 2.4 7.4 1.8 1.3 0.0 0.4 1.0 3.6 4.7 25.0 4.8 4.0 1.1 2.8 3.4 12.1 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C20orf173 dJ477O4.4 ENSG00000125975 "Chromosome 20 open reading frame 173" Q96LM9 20 35523186-35529652 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.5" "Group enriched" "Detected in some" 76 "Early spermatids: 473.3;Late spermatids: 156.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA076859 Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA076859: " "unprognostic (1.90e-1)" "unprognostic (1.03e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 473.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 156.5 4.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 C3orf14 HT021 ENSG00000114405 "Chromosome 3 open reading frame 14" Q9HBI5 3 62319015-62336213 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 159.7;Spermatocytes: 173.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 28.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 408.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048286 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Cytosol "HPA048286: AB_2680340" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "unprognostic (3.69e-3)" "unprognostic (6.91e-2)" "unprognostic (9.19e-2)" "unprognostic (5.76e-5)" "unprognostic (1.57e-3)" "unprognostic (2.67e-1)" "unprognostic (9.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "prognostic favorable (4.33e-5)" "unprognostic (8.19e-2)" "unprognostic (1.73e-2)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" 7.6 15.9 35.4 5.9 37.3 1.3 35.6 32.3 44.5 6.7 23.0 8.3 3.5 7.8 8.1 18.8 4.2 6.5 10.2 37.6 36.7 15.0 3.4 6.9 5.8 32.2 31.4 9.1 12.6 3.8 31.0 5.0 33.0 17.9 4.3 27.2 12.4 5.5 1.3 17.3 4.8 7.1 33.5 4.3 6.2 32.8 33.8 3.7 9.1 1.3 9.2 12.7 9.3 33.0 0.1 22.1 27.2 0.0 18.9 24.8 19.3 33.6 21.2 41.7 41.0 0.3 36.8 0.0 0.1 20.4 84.6 6.7 0.0 21.4 32.1 0.0 14.5 20.5 0.0 0.0 12.0 0.3 45.2 11.3 28.9 47.8 39.6 0.9 21.0 0.0 2.4 0.3 43.0 408.7 0.0 0.0 33.4 31.9 41.9 0.1 0.0 11.8 37.0 64.3 45.9 40.8 21.3 90.0 38.7 20.5 34.0 25.1 0.5 22.2 0.2 105.1 34.8 24.1 0.0 0.0 22.1 0.0 78.4 9.2 4.7 0.7 0.2 17.9 0.0 4.1 3.9 3.3 5.4 1.4 1.1 0.8 0.5 0.9 28.1 7.6 7.9 2.4 35.4 37.3 32.3 44.5 37.6 36.7 32.2 31.4 33.0 33.5 33.8 33.0 8.7 22.4 11.8 11.8 3.3 36.8 23.6 41.5 31.3 34.7 90.2 77.0 7.7 11.5 38.1 22.0 4.2 21.4 8.0 2.6 60.7 35.7 159.7 11.3 14.8 12.1 87.4 2.1 34.8 55.1 19.6 20.9 4.1 12.6 1.3 7.9 5.7 3.1 32.0 37.0 33.4 3.8 44.7 10.0 27.2 62.9 14.0 13.4 46.2 3.7 56.6 35.4 0.0 13.0 15.8 35.8 0.8 10.5 0.5 21.8 2.7 41.5 12.3 28.0 0.0 15.8 21.6 173.2 53.5 30.8 28.7 9.9 5.0 20.6 3.9 23.3 C3orf20 DKFZP434N1817 ENSG00000131379 "Chromosome 3 open reading frame 20" Q8ND61 3 14675141-14773036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 6.6" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Early spermatids: 19.3;Excitatory neurons: 8.4;Inhibitory neurons: 6.9;Late spermatids: 34.6;Oligodendrocytes: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Daudi: 4.0;HEL: 8.2;U-698: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA039584 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA039584: AB_10795152" "unprognostic (1.23e-1)" "unprognostic (2.82e-1)" "unprognostic (5.88e-3)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.76e-3)" "unprognostic (1.81e-1)" "unprognostic (7.82e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (9.08e-2)" "unprognostic (4.74e-2)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-4)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.5 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.2 0.1 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 34.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.5 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C3orf38 MGC26717 ENSG00000179021 "Chromosome 3 open reading frame 38" Q5JPI3 3 88149959-88168729 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 341.2;Late spermatids: 312.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 147.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034736, HPA034737" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 18: U-2197 - ECM organization" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA034736: AB_2674307, HPA034737: AB_10671505" "unprognostic (1.93e-1)" "unprognostic (1.40e-1)" "unprognostic (3.75e-3)" "unprognostic (1.48e-2)" "unprognostic (1.74e-2)" "unprognostic (2.41e-2)" "unprognostic (2.26e-3)" "unprognostic (1.54e-1)" "unprognostic (1.80e-2)" "prognostic favorable (3.55e-4)" "unprognostic (9.28e-3)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.95e-2)" "unprognostic (2.88e-3)" "unprognostic (1.63e-1)" "unprognostic (4.57e-2)" "unprognostic (3.67e-2)" 10.2 8.8 7.1 11.1 9.2 42.1 12.4 11.2 11.5 10.7 6.8 11.1 9.7 9.1 10.9 12.1 10.6 9.7 9.9 7.8 8.6 10.4 14.1 10.1 17.7 8.0 7.5 11.6 7.8 10.7 4.8 12.4 8.6 10.1 11.0 7.7 8.8 9.5 8.0 8.2 10.0 10.9 8.7 13.2 10.4 32.8 7.8 20.9 12.0 10.8 18.4 12.5 5.2 12.8 16.6 17.4 32.5 17.7 22.5 19.8 15.0 26.3 31.5 38.6 51.9 19.5 22.5 22.8 23.1 24.5 18.4 11.8 23.7 19.2 33.1 40.1 11.7 27.1 12.3 16.9 30.8 37.9 22.5 27.7 20.1 26.1 21.8 25.2 23.1 23.7 18.0 25.1 43.4 19.4 38.3 16.9 40.0 31.0 18.8 23.9 11.4 21.5 25.7 22.6 10.1 14.6 24.1 14.2 42.2 26.2 25.5 30.0 20.6 24.2 25.7 147.7 29.8 22.6 36.2 33.0 18.8 29.8 23.0 47.8 22.3 24.1 16.8 32.4 21.4 26.0 15.3 17.2 23.5 22.3 15.1 15.6 9.7 23.4 27.4 16.2 20.5 21.6 7.1 9.2 11.2 11.5 7.8 8.6 8.0 7.5 8.6 8.7 7.8 12.8 13.3 19.2 7.5 5.9 30.9 11.7 18.8 19.9 14.2 21.6 11.0 9.5 6.9 8.6 16.7 5.5 22.9 21.6 24.4 13.9 19.6 16.7 341.2 14.4 13.3 10.8 16.2 23.5 9.7 13.7 22.7 17.3 11.7 10.2 14.0 14.2 11.4 7.5 26.7 6.7 9.1 13.3 14.2 23.9 25.1 312.0 16.4 24.0 16.0 6.5 28.0 23.2 23.7 10.1 15.0 15.3 19.3 15.1 17.5 18.6 16.1 14.5 21.2 24.8 13.1 14.9 16.6 75.7 12.2 14.9 14.1 25.6 24.6 18.1 11.1 22.5 C4orf19 FLJ11017 ENSG00000154274 "Chromosome 4 open reading frame 19" Q8IY42 4 37453925-37623495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 36.0" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Distal enterocytes: 61.3;Exocrine glandular cells: 51.8;Oligodendrocyte precursor cells: 46.8;Pancreatic endocrine cells: 53.6;Paneth cells: 67.2;Proximal enterocytes: 52.3;Syncytiotrophoblasts: 47.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 8.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.6" "Group enriched" "Detected in some" 5 "OE19: 64.6;RT4: 81.0;SK-BR-3: 32.6;T-47d: 113.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043458, HPA052894" Enhanced Supported "Cell Junctions" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA043458: AB_10960696, HPA052894: AB_2681982" "unprognostic (8.83e-2)" "unprognostic (7.86e-2)" "unprognostic (3.00e-3)" "unprognostic (2.04e-2)" "unprognostic (2.23e-1)" "unprognostic (3.59e-3)" "unprognostic (5.55e-2)" "unprognostic (2.29e-1)" "unprognostic (6.66e-2)" "unprognostic (9.96e-2)" "unprognostic (1.35e-1)" "unprognostic (4.38e-2)" "prognostic favorable (1.49e-11)" "unprognostic (1.33e-1)" "unprognostic (1.60e-1)" "unprognostic (1.63e-3)" "unprognostic (8.19e-3)" 3.4 0.3 2.7 3.0 2.9 3.8 3.8 5.3 4.3 10.2 5.9 25.5 17.7 6.7 0.2 2.1 2.8 9.2 0.4 3.5 4.2 12.4 36.0 3.7 0.5 4.9 4.9 0.2 24.9 16.0 1.2 7.6 4.2 1.7 23.7 4.6 28.2 6.8 0.2 1.6 19.6 4.0 4.5 0.3 20.7 1.4 4.9 0.2 1.5 0.4 4.3 8.8 2.9 4.1 0.1 0.2 3.2 0.3 0.0 0.0 4.2 0.7 0.0 0.0 0.0 12.6 5.2 0.1 3.0 0.0 0.1 0.4 0.2 0.8 0.1 0.0 0.4 0.0 8.3 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.1 14.3 0.2 0.2 0.5 64.6 1.7 0.1 7.8 0.2 12.7 81.0 0.9 0.3 0.5 32.6 1.0 4.0 113.1 0.7 0.6 0.4 4.5 0.2 1.6 0.2 0.1 0.5 0.0 6.9 5.6 0.9 1.4 2.1 0.6 0.2 0.4 0.2 0.3 0.4 0.2 0.5 0.5 0.8 8.6 0.8 0.1 1.6 0.7 0.3 2.7 2.9 5.3 4.3 3.5 4.2 4.9 4.9 4.2 4.5 4.9 4.1 0.3 0.0 12.6 45.4 0.7 0.3 7.8 4.9 0.0 0.6 7.1 3.9 0.2 27.1 10.1 11.0 0.0 6.7 0.2 61.3 11.7 25.2 1.2 9.5 0.4 0.9 9.6 0.0 2.3 51.8 4.7 0.3 33.6 5.5 0.0 0.0 0.0 13.1 0.7 0.0 2.4 28.0 4.1 0.0 0.3 2.4 0.0 0.2 3.6 22.5 0.6 5.3 0.0 46.8 1.8 53.6 67.2 0.0 0.0 7.8 52.3 9.2 12.3 1.0 0.0 0.2 0.9 0.3 0.2 0.5 0.0 47.5 0.4 0.1 31.8 19.1 C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA024812: AB_10599490, HPA026104: AB_10600875" "prognostic unfavorable (2.77e-4)" "unprognostic (6.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (8.95e-4)" "unprognostic (4.75e-2)" "unprognostic (3.51e-1)" "unprognostic (2.45e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" 16.5 42.1 32.3 13.1 32.1 18.2 24.8 33.5 41.7 17.7 28.3 21.7 13.1 20.4 27.1 19.5 22.8 16.5 22.3 32.0 33.1 18.7 17.1 15.0 18.2 33.3 34.3 40.7 20.8 34.0 5.6 21.1 32.8 18.8 33.4 24.6 16.4 24.2 16.9 17.4 10.2 19.6 32.4 12.2 11.5 13.1 32.7 19.3 33.2 26.0 18.4 18.8 8.9 33.3 28.3 32.7 45.8 22.7 51.3 35.5 17.2 16.6 41.7 42.0 23.3 9.2 39.2 30.3 55.3 40.5 19.5 22.4 67.5 41.2 45.3 15.0 48.4 38.1 32.1 11.5 53.1 30.6 15.1 41.0 60.4 43.0 96.8 34.5 28.1 44.9 75.4 26.3 46.1 42.4 86.3 12.3 31.8 89.1 55.2 51.2 14.9 46.6 44.1 16.3 44.1 39.1 44.3 39.3 39.0 26.1 41.1 29.1 13.8 27.5 37.3 24.2 37.8 21.7 16.9 72.2 65.9 47.0 55.1 1.0 13.7 8.7 16.3 17.4 18.4 13.4 16.2 17.8 19.6 13.3 21.3 15.6 1.4 28.2 16.0 18.4 12.6 16.3 32.3 32.1 33.5 41.7 32.0 33.1 33.3 34.3 32.8 32.4 32.7 33.3 67.8 28.9 27.2 4.9 34.8 44.4 32.8 31.9 24.5 48.3 52.8 47.9 18.4 45.8 33.8 25.8 31.3 36.9 45.3 180.5 62.6 79.5 5.6 49.9 55.1 50.2 35.3 17.5 5.7 64.9 40.2 41.7 20.9 53.0 21.5 58.5 37.1 66.8 28.7 50.5 6.0 36.4 14.2 21.5 21.2 5.6 37.9 23.0 16.0 7.5 32.3 61.2 45.3 4.0 6.0 55.3 37.7 38.7 20.4 48.1 22.1 66.1 26.6 54.5 26.3 32.8 37.9 26.2 34.8 25.4 42.9 24.9 23.6 94.9 53.0 28.5 C8orf37 "BBS21, CORD16, FAP418, FLJ30600, MOT25, RP64" ENSG00000156172 "Chromosome 8 open reading frame 37" Q96NL8 8 95244913-95269201 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Bardet-Biedl syndrome, Ciliopathy, Cone-rod dystrophy, Disease variant, Obesity, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024198 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Plasma membrane, Cell Junctions" "HPA024198: AB_1845775" "unprognostic (7.90e-2)" "unprognostic (1.98e-2)" "unprognostic (5.68e-2)" "prognostic unfavorable (4.63e-4)" "unprognostic (2.72e-3)" "unprognostic (4.20e-3)" "unprognostic (2.04e-2)" "unprognostic (8.94e-2)" "unprognostic (1.81e-1)" "unprognostic (1.76e-1)" "unprognostic (6.11e-3)" "unprognostic (2.32e-1)" "unprognostic (1.09e-1)" "unprognostic (6.72e-3)" "unprognostic (2.02e-1)" "unprognostic (1.33e-2)" "unprognostic (3.29e-1)" 1.7 1.8 1.7 1.2 1.9 0.9 2.3 2.3 2.2 2.3 3.2 1.0 0.9 2.4 3.1 1.0 3.9 1.4 2.7 1.7 1.8 2.4 1.8 1.5 2.2 2.3 2.9 4.8 1.2 3.5 2.3 1.8 2.2 2.0 0.9 5.0 1.5 1.7 1.1 1.5 1.0 2.3 2.7 1.7 1.1 1.7 1.8 2.4 2.4 1.8 1.9 1.2 1.4 2.9 2.8 4.5 3.6 1.9 1.2 3.3 1.0 1.2 2.7 1.5 2.0 0.7 6.0 5.6 2.8 2.0 3.8 2.3 1.5 3.1 3.3 1.8 1.4 4.4 2.7 2.0 1.4 0.9 2.3 3.3 1.4 1.8 5.0 3.9 2.3 3.3 2.3 3.2 2.0 2.1 4.8 1.1 1.1 5.6 3.0 2.5 1.9 1.4 3.4 1.2 3.5 3.4 2.5 0.5 2.1 2.7 4.2 0.8 2.0 1.9 2.4 1.6 1.2 2.9 3.0 3.8 3.6 2.1 2.4 0.3 0.3 0.1 0.2 0.2 0.5 0.4 0.3 0.3 0.5 0.8 0.3 0.5 0.4 0.7 0.1 0.2 0.1 0.2 1.7 1.9 2.3 2.2 1.7 1.8 2.3 2.9 2.2 2.7 1.8 2.9 2.4 3.2 2.6 6.8 2.5 0.9 3.7 2.9 4.0 2.7 1.3 2.4 5.3 0.0 3.3 7.3 2.1 2.5 1.8 0.1 7.9 1.8 10.2 3.4 1.3 1.5 0.0 0.4 6.8 2.7 2.9 2.8 1.1 1.0 0.0 1.9 1.1 3.8 1.3 3.3 5.2 0.1 2.0 1.6 1.2 8.7 3.1 0.8 1.8 1.9 1.8 5.3 0.0 8.5 5.7 1.2 0.2 3.0 0.7 1.9 0.1 4.7 7.9 4.1 0.0 2.5 4.2 6.0 3.5 0.9 1.8 0.8 1.1 3.0 0.5 1.8 C9orf153 bA507D14.1 ENSG00000187753 "Chromosome 9 open reading frame 153" Q5TBE3 9 86220265-86259657 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 20.8" "Group enriched" "Detected in some" 26 "Early spermatids: 268.6;Late spermatids: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in single" "HeLa: 1.3" "Not detected" "Not detected" HPA079466 Approved "Nucleoplasm,Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Nuclear bodies, Plasma membrane" "Nucleoplasm, Vesicles" "HPA079466: " "unprognostic (2.03e-1)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (2.33e-2)" "unprognostic (1.78e-1)" "unprognostic (5.30e-3)" "unprognostic (7.49e-2)" "unprognostic (2.75e-2)" "unprognostic (3.37e-1)" "unprognostic (6.85e-2)" "unprognostic (9.70e-2)" "unprognostic (1.49e-1)" "unprognostic (2.01e-6)" "unprognostic (9.43e-2)" "unprognostic (1.92e-1)" "unprognostic (9.64e-2)" "unprognostic (2.10e-1)" 0.1 0.4 0.3 0.4 0.2 2.6 0.2 1.4 0.9 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.5 0.5 0.6 0.2 0.1 0.1 0.0 0.9 0.6 0.1 0.1 0.6 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.2 0.3 20.8 0.5 0.1 0.2 0.1 0.0 0.0 0.0 1.3 0.2 0.8 0.0 0.4 0.0 0.4 0.3 0.2 0.0 0.0 0.2 0.0 0.6 0.8 0.2 0.2 0.5 0.2 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.2 0.1 0.2 0.2 0.1 0.6 0.1 0.0 0.0 0.3 0.9 0.0 0.5 0.1 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.7 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.6 0.1 0.2 0.4 0.1 0.3 0.0 0.1 0.4 0.8 1.6 0.2 0.3 0.6 0.1 0.1 0.1 0.1 1.2 0.2 0.1 0.1 0.5 0.3 0.2 0.2 0.1 1.5 0.3 0.2 1.4 0.9 0.2 0.2 0.5 0.6 0.6 0.0 0.5 1.3 0.3 0.0 0.0 9.8 0.1 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 268.6 0.4 0.5 0.7 0.0 0.0 4.8 0.0 0.1 0.4 0.0 0.5 0.0 0.4 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.4 244.8 2.8 0.1 1.8 1.0 0.1 0.4 2.1 6.6 9.7 0.1 0.0 0.7 0.4 0.3 0.0 0.1 0.0 0.1 0.0 1.3 0.7 1.8 1.9 0.0 0.1 0.1 0.2 0.3 0.1 0.2 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CABLES2 "C20orf150, dJ908M14.2, ik3-2" ENSG00000149679 "Cdk5 and Abl enzyme substrate 2" Q9BTV7 20 62388632-62407285 "Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 31.0" "Cell type enhanced" "Detected in many" "Early spermatids: 51.3;Late spermatids: 25.6;Spermatocytes: 21.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052138 Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nuclear bodies" "Nucleoplasm, Cell Junctions" "HPA052138: AB_2681743" "unprognostic (1.08e-1)" "unprognostic (1.36e-2)" "unprognostic (2.25e-1)" "prognostic unfavorable (5.26e-5)" "unprognostic (1.45e-2)" "unprognostic (1.51e-1)" "unprognostic (2.71e-2)" "unprognostic (5.07e-2)" "unprognostic (5.37e-3)" "unprognostic (6.05e-2)" "unprognostic (1.40e-3)" "unprognostic (3.09e-2)" "prognostic unfavorable (1.24e-6)" "unprognostic (1.99e-2)" "unprognostic (3.87e-1)" "unprognostic (1.67e-1)" "unprognostic (2.94e-2)" 2.4 3.0 6.8 4.2 7.2 8.1 2.8 11.5 9.1 3.9 3.5 4.4 2.9 3.5 2.6 3.2 4.8 2.2 10.6 7.1 7.4 2.6 4.0 2.9 5.1 7.9 6.6 4.3 3.2 3.9 5.9 2.8 7.8 4.3 3.2 5.6 3.3 3.1 5.8 4.3 4.4 3.3 5.9 4.2 4.0 31.0 7.5 5.3 5.1 4.1 4.4 3.7 3.3 7.2 16.3 12.0 20.4 20.9 3.1 4.4 2.8 9.2 8.9 24.8 11.4 43.6 9.1 16.3 7.6 5.9 33.9 10.1 12.6 6.0 9.6 7.3 6.9 19.0 6.3 10.6 5.5 7.8 9.4 2.7 6.7 7.1 2.6 4.4 5.8 20.8 4.9 13.9 5.6 20.0 20.6 6.2 6.8 16.4 13.7 28.1 17.2 7.1 3.7 10.6 11.1 16.8 13.3 17.4 3.6 7.6 11.9 11.7 6.0 22.7 6.8 30.3 9.5 13.3 11.7 19.4 20.4 8.8 12.1 0.0 0.2 0.0 0.7 0.3 0.4 0.5 0.4 0.5 0.3 0.2 0.2 0.3 0.2 0.4 0.3 0.2 1.3 0.1 6.8 7.2 11.5 9.1 7.1 7.4 7.9 6.6 7.8 5.9 7.5 7.2 1.5 3.2 1.7 2.0 2.1 0.9 0.5 1.7 2.8 6.0 2.9 2.4 10.7 2.8 2.5 0.0 4.2 1.3 3.1 3.5 1.9 2.2 51.3 1.1 1.2 1.6 3.5 1.7 4.4 2.4 0.7 2.6 3.6 2.2 0.0 5.3 2.2 1.4 2.1 13.5 5.2 4.1 0.0 1.6 3.0 25.6 1.8 2.0 0.0 1.0 1.0 1.9 1.0 3.5 3.3 2.1 2.3 3.4 2.5 0.7 1.8 0.7 0.2 3.4 0.0 3.0 1.3 21.8 6.9 1.3 2.0 2.3 2.0 1.0 2.8 0.6 CACNA1E "BII, CACH6, CACNL1A6, Cav2.3" ENSG00000198216 "Calcium voltage-gated channel subunit alpha1 E" Q15878 1 181317690-181808084 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 28 "brain: 42.8" "Cell type enhanced" "Detected in some" "Excitatory neurons: 188.7;Inhibitory neurons: 116.0;Oligodendrocyte precursor cells: 73.9;Oligodendrocytes: 34.2" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.6;NB-4: 1.0;NTERA-2: 1.1;U-266/70: 2.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042515, CAB079032" Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments, Cytosol" "CAB079032: , HPA042515: " "unprognostic (3.96e-3)" "unprognostic (1.89e-1)" "unprognostic (1.05e-2)" "unprognostic (1.54e-5)" "unprognostic (6.56e-2)" "unprognostic (3.16e-2)" "unprognostic (4.30e-3)" "unprognostic (1.18e-1)" "unprognostic (2.40e-1)" "unprognostic (9.48e-3)" "unprognostic (1.04e-1)" "unprognostic (2.06e-1)" "unprognostic (9.85e-7)" "unprognostic (1.74e-2)" "unprognostic (2.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.75e-2)" 0.0 1.0 33.5 0.6 30.5 1.2 0.0 0.0 34.6 0.0 0.0 0.1 0.0 0.0 1.5 0.2 0.7 0.0 0.3 42.8 3.4 1.3 0.0 0.1 0.4 4.6 6.2 0.0 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.2 0.2 9.7 0.4 0.1 1.0 3.8 0.0 0.0 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.1 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 33.5 30.5 0.0 34.6 42.8 3.4 4.6 6.2 0.9 9.7 3.8 1.1 0.0 0.0 0.0 3.6 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.4 0.0 0.0 188.7 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 116.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 6.5 0.0 0.2 0.0 73.9 34.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;thyroid gland: 5.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 16.9;Excitatory neurons: 16.8;Inhibitory neurons: 12.3" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-BR-3: 1.9;T-47d: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066992 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Cell Junctions" "HPA066992: " "unprognostic (3.97e-2)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-1)" "unprognostic (7.21e-2)" "unprognostic (5.20e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-2)" "unprognostic (6.14e-3)" "unprognostic (1.57e-1)" "unprognostic (3.78e-2)" "unprognostic (8.27e-4)" 0.2 3.3 5.0 0.8 5.6 0.6 0.1 1.5 9.7 0.1 0.0 0.5 0.1 0.1 0.0 0.2 0.2 0.1 0.0 8.7 1.3 0.1 0.0 0.5 1.9 7.6 1.4 0.0 0.1 0.0 0.3 0.0 7.9 0.1 0.0 2.6 0.1 0.0 0.0 0.2 3.3 0.0 0.7 1.5 0.6 0.8 2.2 0.2 5.3 0.0 0.5 0.4 0.2 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 5.0 5.6 1.5 9.7 8.7 1.3 7.6 1.4 7.9 0.7 2.2 4.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 16.9 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.4 16.8 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 3.3 12.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 1.0 2.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.1 CADM1 "BL2, IGSF4, IGSF4A, Necl-2, NECL2, RA175, ST17, SYNCAM, SYNCAM1, TSLC1" ENSG00000182985 "Cell adhesion molecule 1" Q9BY67 11 115169218-115504957 "Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Differentiation, Host-virus interaction, Immunity, Spermatogenesis" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 287.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 464.8;Astrocytes: 980.7;Bipolar cells: 566.6;Muller glia cells: 489.9;Oligodendrocyte precursor cells: 676.5;Oligodendrocytes: 622.8;Rod photoreceptor cells: 759.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 8.0;myeloid DC: 8.1" "Group enriched" "Detected in many" 5 "dendritic cells: 8.1;T-cells: 8.0" "Cell line enhanced" "Detected in many" "CACO-2: 294.7;WM-115: 187.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB037266 Enhanced Supported "Cell Junctions" NA NA 220000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 39: CACO-2 - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "CAB037266: AB_532287" "unprognostic (1.50e-1)" "unprognostic (2.15e-1)" "unprognostic (1.92e-2)" "prognostic favorable (1.32e-4)" "unprognostic (4.11e-3)" "unprognostic (1.50e-1)" "unprognostic (2.75e-3)" "unprognostic (1.13e-2)" "unprognostic (1.77e-1)" "unprognostic (2.67e-1)" "unprognostic (6.61e-3)" "unprognostic (9.22e-2)" "unprognostic (2.92e-3)" "unprognostic (1.77e-2)" "unprognostic (1.54e-1)" "unprognostic (3.67e-2)" "unprognostic (5.40e-2)" 7.1 29.9 46.9 6.1 59.2 0.4 17.0 78.7 53.0 21.3 6.1 11.7 7.8 17.4 103.7 12.6 22.6 12.1 25.7 47.6 57.4 29.1 65.3 72.0 14.1 41.1 40.1 12.3 16.0 56.6 26.0 37.9 44.6 15.2 8.1 287.7 38.0 28.0 7.2 10.9 8.8 8.6 30.3 8.0 12.5 50.5 55.8 8.6 69.7 8.1 14.6 13.1 4.8 38.0 0.4 23.3 25.6 0.1 0.0 0.0 0.1 24.1 41.1 3.1 0.3 294.7 26.1 0.0 75.9 36.5 25.2 4.8 4.8 27.4 2.0 1.0 38.3 0.0 7.8 114.5 0.3 0.1 56.5 0.0 38.6 0.0 63.8 16.5 1.1 17.3 0.0 2.7 4.3 19.3 20.0 0.6 24.0 0.3 0.0 0.1 0.4 61.6 44.8 0.9 50.2 107.1 0.0 25.4 21.7 102.4 92.4 1.3 0.0 2.3 44.9 23.3 13.0 64.9 98.9 18.7 36.3 0.2 187.5 0.2 0.0 0.0 8.0 0.0 3.4 1.5 2.9 2.1 8.1 0.3 0.1 1.8 0.0 0.5 0.1 0.0 4.7 1.9 46.9 59.2 78.7 53.0 47.6 57.4 41.1 40.1 44.6 30.3 55.8 38.0 14.0 464.8 195.3 980.7 6.5 20.6 26.7 2.8 19.4 566.6 22.1 22.5 61.7 34.3 27.5 36.8 350.3 71.6 6.8 1.5 11.7 39.2 189.1 88.5 6.0 10.6 7.8 5.3 301.7 2.0 5.0 13.2 3.6 126.9 24.1 36.8 2.9 45.9 36.8 30.3 310.9 2.1 4.1 8.5 20.9 224.0 5.9 14.2 44.4 60.0 13.3 489.9 2.1 676.5 622.8 9.3 0.5 4.1 88.9 38.5 0.3 8.2 8.7 759.5 0.0 13.3 11.7 55.2 23.0 9.2 23.4 32.2 8.1 5.2 4.3 13.5 CALCR CTR ENSG00000004948 "Calcitonin receptor" 7 93424486-93574730 "Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.8;kidney: 1.5" "Cell type enhanced" "Detected in some" "Early spermatids: 16.5;Late spermatids: 7.7;Microglial cells: 15.9;Skeletal myocytes: 46.0" "Cancer enriched" "Detected in single" 5 "renal cancer: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPTEC TERT1: 1.6;SuSa: 2.9;T-47d: 2.7" "Group enriched" "Detected in many" 5 "basal ganglia: 6.3;hypothalamus: 24.6" "Low region specificity" "Detected in all" "HPA028962, HPA061428" Enhanced Supported Approved "Vesicles,Cell Junctions,Centriolar satellite" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "Vesicles, Centriolar satellite" "HPA028962: AB_10602339, HPA061428: AB_2732661" "unprognostic (1.95e-1)" "unprognostic (2.43e-1)" "unprognostic (3.88e-2)" "unprognostic (1.88e-1)" "unprognostic (1.55e-2)" "unprognostic (3.43e-1)" "unprognostic (7.73e-5)" "unprognostic (1.64e-1)" "unprognostic (9.24e-3)" "unprognostic (8.70e-2)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (2.71e-3)" "unprognostic (1.46e-3)" "unprognostic (1.69e-1)" "unprognostic (2.49e-4)" "unprognostic (1.05e-2)" 0.1 0.2 1.6 0.0 0.5 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 5.8 1.5 0.0 0.2 0.0 1.8 1.6 0.2 0.0 0.0 0.1 0.6 3.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.0 2.9 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.5 0.0 0.2 0.0 5.8 1.8 1.6 3.4 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.8 0.6 7.7 0.6 0.6 0.0 15.9 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.0 0.0 3.4 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116558868 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 23.1" "Group enriched" "Detected in some" 24 "Cytotrophoblasts: 28.2;Syncytiotrophoblasts: 54.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA048014: " "unprognostic (7.95e-2)" "unprognostic (3.44e-4)" "unprognostic (1.99e-1)" "unprognostic (1.44e-2)" 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 23.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.6 0.0 0.2 0.0 0.0 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 11.3;brain: 44.3;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "Astrocytes: 88.8;Excitatory neurons: 130.6;Inhibitory neurons: 212.7;Oligodendrocyte precursor cells: 44.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Karpas-707: 44.5" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Plasma membrane" "HPA036278: AB_10673125, HPA036708: " "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-2)" "unprognostic (3.67e-4)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (7.72e-4)" "unprognostic (2.99e-1)" 0.1 11.3 12.2 0.0 18.5 0.6 0.2 44.3 15.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 25.4 40.6 0.0 0.2 0.0 0.0 27.9 17.0 0.1 1.0 0.0 0.5 0.0 30.2 0.2 0.1 1.9 0.0 1.1 0.0 3.5 0.0 0.0 15.2 0.0 0.0 3.2 8.3 24.7 0.1 0.0 0.0 0.0 3.2 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.5 0.0 0.0 0.1 0.0 6.0 0.0 0.0 7.1 0.0 0.8 0.0 0.0 6.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 7.2 0.1 0.0 7.0 7.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 18.5 44.3 15.0 25.4 40.6 27.9 17.0 30.2 15.2 8.3 26.5 0.0 0.0 0.0 88.8 0.0 2.3 0.4 0.0 0.0 3.8 0.0 0.6 5.6 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 0.1 0.1 0.3 0.0 2.1 130.6 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.4 0.4 0.1 0.0 212.7 1.5 0.0 0.3 0.7 7.0 0.0 0.1 0.0 14.0 0.0 0.2 1.0 44.7 15.7 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.0 0.8 0.0 6.1 0.2 8.8 12.8 0.0 9.8 0.1 0.2 0.2 0.1 0.1 CAMK2A "CAMKA, CaMKIIα, CaMKIINalpha, KIAA0968" ENSG00000070808 "Calcium/calmodulin dependent protein kinase II alpha" Q9UQM7 5 150219491-150290291 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 662.9" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 245.8" "Cancer enriched" "Detected in single" 13 "glioma: 6.0" "Region enhanced" "Detected in many" "cerebral cortex: 662.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 1.3;SCLC-21H: 3.0;SuSa: 1.4;U-87 MG: 3.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 1071.1" "CAB004330, HPA051783, HPA051785, HPA053973" Supported Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 66000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Cell Junctions, Cytosol" "CAB004330: AB_626788, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (7.20e-3)" "unprognostic (6.47e-3)" "unprognostic (6.16e-3)" "unprognostic (4.85e-2)" "unprognostic (4.25e-2)" "unprognostic (1.06e-3)" "unprognostic (1.13e-1)" "unprognostic (6.19e-3)" "unprognostic (3.07e-1)" "unprognostic (1.05e-1)" "unprognostic (4.49e-2)" "unprognostic (1.41e-2)" "unprognostic (2.00e-8)" "unprognostic (2.71e-4)" "unprognostic (1.68e-1)" "unprognostic (1.70e-2)" "unprognostic (1.36e-3)" 0.2 0.9 161.7 0.2 230.9 0.1 0.1 0.0 662.9 1.2 0.0 1.0 0.1 2.8 0.3 1.3 1.5 0.3 4.8 453.1 0.0 0.7 0.2 0.9 0.0 0.0 0.0 0.4 0.1 0.0 3.5 0.3 0.0 0.8 0.2 1.9 0.7 0.4 95.0 0.7 0.4 2.4 0.0 0.3 0.5 0.1 0.0 0.0 0.1 34.7 0.0 2.0 0.7 99.6 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.8 0.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.9 0.0 0.7 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.0 0.0 0.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 3.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 161.7 230.9 0.0 662.9 453.1 0.0 0.0 0.0 0.0 0.0 0.0 99.6 0.0 0.0 0.0 12.1 0.0 3.4 0.0 0.0 0.0 5.1 0.0 0.0 14.9 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.0 0.0 245.8 0.0 0.1 2.2 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.0 55.5 0.0 0.0 0.0 0.8 0.3 0.0 0.0 3.6 9.4 0.0 0.4 0.0 8.5 8.1 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.1 0.0 3.6 1.8 0.0 0.3 0.0 1.4 0.3 0.2 0.0 0.0 0.0 CAMK2B "CAM2, CAMK2, CAMKB, CaMKIIβ" ENSG00000058404 "Calcium/calmodulin dependent protein kinase II beta" Q13554 7 44217150-44334577 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Actin-binding, Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 248.8;skeletal muscle: 132.5" "Cell type enriched" "Detected in many" 7 "Bipolar cells: 857.4" "Cancer enhanced" "Detected in many" "glioma: 6.0;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 75.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006849, HPA026307, HPA051783, HPA051785, HPA053973" Enhanced Supported Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA 600000 "Cluster 11: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "Cell Junctions, Cytosol" "CAB006849: , HPA026307: AB_1845941, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (1.88e-3)" "unprognostic (4.49e-2)" "unprognostic (3.55e-3)" "unprognostic (1.36e-2)" "unprognostic (5.25e-2)" "unprognostic (2.90e-2)" "unprognostic (8.78e-2)" "unprognostic (1.09e-1)" "unprognostic (1.44e-1)" "unprognostic (2.71e-1)" "unprognostic (1.17e-2)" "unprognostic (1.60e-2)" "unprognostic (5.23e-7)" "unprognostic (7.04e-2)" "unprognostic (2.34e-1)" "unprognostic (3.15e-2)" "unprognostic (3.95e-2)" 0.5 11.3 77.9 0.6 109.0 0.1 1.4 113.0 248.8 0.1 0.0 1.0 1.0 0.2 28.3 1.4 1.1 0.2 65.4 197.6 12.6 1.6 7.7 0.3 1.3 4.4 11.9 0.3 3.8 6.1 51.3 0.1 4.6 3.2 0.4 21.4 1.4 1.6 132.5 1.2 0.9 0.1 3.2 0.3 2.3 2.1 25.9 0.8 20.3 59.2 1.6 0.0 0.3 80.4 0.0 0.8 0.4 0.6 0.0 0.4 0.4 0.3 0.1 0.3 0.0 0.3 0.1 0.2 1.6 0.4 0.1 0.3 0.4 1.4 0.1 2.0 4.5 0.1 0.2 0.2 0.1 0.0 0.9 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.8 0.1 10.1 0.0 0.4 0.2 0.1 4.4 0.2 1.7 0.3 0.0 0.0 75.5 4.0 0.4 0.0 0.0 0.1 3.5 0.3 0.4 0.5 0.7 0.4 0.1 0.9 0.8 0.2 0.2 0.0 0.5 1.0 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.2 0.2 0.4 0.7 0.3 0.2 0.2 0.2 77.9 109.0 113.0 248.8 197.6 12.6 4.4 11.9 4.6 3.2 25.9 80.4 0.1 0.0 0.0 67.3 0.2 1.1 21.5 0.0 10.8 857.4 3.1 17.5 88.9 2.8 0.0 0.0 45.9 0.1 0.0 0.5 9.8 0.0 0.9 2.3 0.4 1.6 40.7 0.0 111.4 0.0 0.2 2.9 4.1 5.6 4.5 15.4 0.0 4.3 0.2 60.6 90.9 1.5 2.0 0.6 0.4 2.9 1.8 0.5 1.8 5.6 0.0 23.2 0.0 19.6 5.4 0.1 1.2 0.0 0.1 3.3 0.1 1.9 0.0 53.1 0.0 6.9 1.7 0.2 7.8 0.9 0.4 0.3 0.2 0.2 0.3 6.6 CAMK2D CAMKD ENSG00000145349 "Calcium/calmodulin dependent protein kinase II delta" Q13557 4 113451032-113761927 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 159.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 272.9;Excitatory neurons: 182.9;Inhibitory neurons: 200.0;Microglial cells: 187.4;Oligodendrocyte precursor cells: 203.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 272.6" "Low region specificity" "Detected in all" "HPA026281, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 240000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA026281: AB_1845944, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (2.14e-2)" "unprognostic (3.17e-1)" "unprognostic (2.13e-1)" "unprognostic (7.49e-2)" "unprognostic (2.19e-1)" "unprognostic (5.09e-1)" "unprognostic (4.26e-2)" "unprognostic (1.17e-1)" "unprognostic (2.26e-1)" "unprognostic (2.62e-1)" "unprognostic (7.81e-2)" "unprognostic (7.91e-3)" "unprognostic (2.62e-2)" "unprognostic (1.46e-1)" "unprognostic (9.68e-2)" "unprognostic (1.87e-1)" "unprognostic (1.90e-2)" 28.6 25.6 52.7 26.6 45.1 5.7 21.0 45.8 52.0 18.9 1.6 36.4 28.8 23.5 9.8 29.7 18.8 30.7 159.3 60.2 23.9 19.3 37.3 22.9 35.2 11.8 33.9 25.4 15.2 56.5 9.1 19.8 12.6 32.2 39.1 79.2 13.4 41.7 105.1 15.8 34.1 24.9 21.0 18.4 37.1 19.8 46.7 16.3 23.7 60.0 31.4 27.4 19.7 22.9 4.8 62.5 67.5 22.8 144.0 272.6 24.0 145.4 96.3 56.0 48.0 42.3 17.6 91.2 20.7 102.3 70.7 2.1 42.6 22.8 56.6 35.1 10.8 0.0 22.0 49.2 73.0 0.1 0.2 176.3 30.5 43.5 107.1 88.5 50.6 11.3 3.6 39.4 106.8 17.1 9.3 3.6 9.8 60.3 22.8 17.9 79.0 0.4 57.3 42.7 18.2 18.3 20.0 29.3 19.5 55.9 0.6 23.7 30.7 146.9 34.8 63.6 29.1 30.4 16.5 76.7 75.7 5.5 70.8 0.0 12.7 0.0 6.7 7.0 12.7 11.2 6.6 7.5 15.7 22.6 7.4 6.5 0.9 9.7 2.5 0.1 13.2 7.7 52.7 45.1 45.8 52.0 60.2 23.9 11.8 33.9 12.6 21.0 46.7 22.9 43.7 41.7 37.6 128.3 55.1 18.4 16.6 8.3 22.8 83.3 14.0 17.1 272.9 62.9 24.7 29.5 87.6 0.5 19.0 70.9 5.9 8.4 3.2 18.2 35.2 27.2 103.8 3.6 182.9 20.1 0.4 50.1 71.9 47.0 10.1 13.0 24.3 57.2 18.6 72.3 200.0 88.1 14.2 17.3 22.3 6.2 20.2 31.5 5.4 187.4 16.0 35.9 28.8 203.1 128.0 11.6 57.3 19.9 20.4 36.2 52.4 23.1 21.7 74.0 6.6 32.8 44.4 3.1 3.4 37.1 31.8 1.1 27.8 12.3 48.6 27.5 CAMK2G CAMKG ENSG00000148660 "Calcium/calmodulin dependent protein kinase II gamma" Q13555 10 73812501-73874591 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Neurogenesis" "Calmodulin-binding, Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 154.3" "Cell type enhanced" "Detected in many" "Astrocytes: 410.7;Cytotrophoblasts: 163.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 133.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "PC-3: 154.8;SK-BR-3: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040656, HPA051783, HPA051785, HPA053973" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA 200000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Cell Junctions, Cytosol" "HPA040656: AB_2677065, HPA051783: AB_2681608, HPA051785: AB_2681609, HPA053973: AB_2682328" "unprognostic (8.63e-3)" "unprognostic (2.01e-1)" "unprognostic (1.05e-1)" "unprognostic (3.46e-3)" "unprognostic (4.27e-2)" "unprognostic (1.82e-2)" "unprognostic (2.19e-2)" "unprognostic (2.36e-1)" "unprognostic (2.48e-1)" "unprognostic (6.25e-2)" "unprognostic (2.92e-2)" "unprognostic (1.08e-1)" "unprognostic (1.73e-2)" "unprognostic (2.48e-1)" "unprognostic (8.28e-2)" "unprognostic (9.64e-2)" "unprognostic (4.62e-2)" 22.0 14.0 86.1 17.0 92.6 34.5 15.2 79.9 137.8 24.1 44.1 101.1 34.2 45.2 14.5 34.7 30.6 17.8 11.8 91.3 79.0 19.3 14.5 18.8 16.2 96.1 96.5 12.7 10.3 12.3 14.1 27.3 94.1 31.1 26.1 42.4 22.9 49.6 154.3 17.3 41.5 43.9 91.4 24.9 30.4 6.5 102.5 15.7 13.6 84.8 14.9 58.4 25.8 91.9 35.7 24.6 22.5 43.9 16.7 26.1 26.3 25.8 41.0 31.9 26.1 39.8 37.2 27.4 25.7 32.4 12.4 54.9 17.5 20.5 25.3 24.0 22.2 18.2 20.4 17.8 8.1 24.7 29.1 14.4 17.7 32.5 22.1 50.4 28.3 32.5 19.5 37.9 19.0 25.2 41.7 37.5 16.5 21.3 154.8 36.5 25.3 13.7 17.2 51.5 11.5 28.4 15.0 177.4 11.9 16.5 33.2 15.0 36.7 24.9 40.0 13.4 33.3 11.9 14.9 24.8 26.5 69.2 8.8 31.0 17.9 133.9 23.1 7.9 28.5 13.9 26.3 25.0 23.0 12.7 24.5 24.1 115.8 34.0 15.1 7.9 27.7 17.5 86.1 92.6 79.9 137.8 91.3 79.0 96.1 96.5 94.1 91.4 102.5 91.9 19.3 16.0 11.7 410.7 22.2 9.4 8.7 9.2 14.2 63.3 14.8 16.3 6.7 12.8 15.5 7.3 100.1 163.6 21.3 46.2 13.7 13.3 2.0 6.3 6.4 20.2 23.9 13.3 107.9 19.6 45.2 12.0 14.8 7.5 16.5 20.2 16.4 9.6 27.2 26.9 89.7 24.8 10.2 18.9 16.3 3.1 12.8 15.8 12.4 43.1 18.3 17.7 26.8 61.9 16.9 22.0 65.5 18.8 13.6 8.2 77.1 26.9 10.4 77.0 46.0 11.2 50.8 0.8 13.5 26.5 12.6 81.1 30.3 5.2 32.1 13.7 CAP2 ENSG00000112186 "Cyclase associated actin cytoskeleton regulatory protein 2" P40123 6 17393505-17557790 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 577.1;tongue: 313.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 126.5;Excitatory neurons: 158.1;Inhibitory neurons: 137.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 26.1;basal ganglia: 40.9;cerebral cortex: 87.2;hippocampal formation: 50.2;white matter: 32.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "LHCN-M2: 101.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050530, HPA054147" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA050530: AB_2681159, HPA054147: AB_2682400" "unprognostic (7.27e-2)" "unprognostic (5.71e-3)" "unprognostic (1.63e-2)" "unprognostic (1.55e-1)" "unprognostic (4.86e-1)" "unprognostic (2.23e-2)" "unprognostic (9.94e-2)" "unprognostic (3.58e-2)" "unprognostic (7.72e-2)" "unprognostic (1.65e-1)" "unprognostic (6.43e-2)" "unprognostic (2.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.06e-2)" "unprognostic (1.47e-1)" "unprognostic (8.05e-2)" "unprognostic (1.75e-3)" 17.8 11.6 26.1 7.6 40.9 0.0 10.7 0.9 87.2 15.4 2.9 32.6 4.1 28.5 17.8 21.7 16.8 11.4 113.6 50.2 11.1 8.7 4.5 4.7 1.7 3.2 3.8 4.5 4.2 7.5 5.1 8.8 2.7 25.1 9.6 9.1 7.7 30.7 577.1 2.6 8.9 42.7 0.0 3.1 9.8 1.5 9.1 3.1 5.5 313.0 2.3 14.5 6.4 32.3 15.5 24.6 44.4 55.1 0.3 0.1 10.4 52.3 42.7 46.6 43.0 8.1 6.9 0.0 48.9 62.1 60.5 8.2 21.3 20.9 66.8 0.1 7.9 0.0 15.4 26.5 4.3 0.0 0.0 3.5 9.9 23.1 10.3 72.3 2.2 0.0 0.0 0.1 101.6 25.2 0.0 0.0 17.0 0.8 15.6 5.2 59.1 1.1 23.6 6.4 6.1 10.9 19.0 59.2 31.3 82.8 65.0 11.2 0.2 36.6 31.6 1.0 47.6 0.0 0.0 0.2 11.7 0.1 48.4 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.1 40.9 0.9 87.2 50.2 11.1 3.2 3.8 2.7 0.0 9.1 32.3 2.0 3.2 1.5 9.8 0.0 1.9 4.3 6.2 5.7 16.4 10.2 8.4 126.5 4.3 5.4 1.8 4.2 16.5 0.0 1.9 3.9 2.7 0.1 13.9 13.7 2.7 6.0 0.0 158.1 0.7 12.2 7.9 0.0 5.8 0.0 22.8 3.9 2.4 2.2 8.4 137.2 1.3 2.0 0.0 2.2 0.0 0.6 0.3 0.0 10.3 0.0 6.3 0.0 16.6 7.2 3.7 1.9 4.9 0.0 1.9 0.0 16.7 33.9 2.2 32.9 25.5 43.4 0.1 3.2 2.1 0.9 37.5 0.3 0.3 1.6 0.6 CAPS "CAPS1, MGC126562" ENSG00000105519 Calcyphosine Q13938 19 5912339-5916211 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 334.8" "Group enriched" "Detected in many" 6 "Endometrial ciliated cells: 2622.9;Respiratory ciliated cells: 1557.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 171.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "OE19: 19.4;SK-BR-3: 65.1;U-266/70: 19.8" "Low region specificity" "Detected in all" HPA043520 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA043520: AB_10964138" "unprognostic (2.06e-1)" "unprognostic (1.13e-2)" "unprognostic (7.94e-3)" "prognostic favorable (7.63e-5)" "unprognostic (5.18e-1)" "prognostic favorable (8.60e-4)" "unprognostic (7.07e-2)" "unprognostic (2.46e-3)" "unprognostic (1.51e-1)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (9.99e-2)" "unprognostic (4.01e-2)" "unprognostic (8.47e-2)" "unprognostic (3.25e-1)" "unprognostic (6.86e-3)" "unprognostic (5.96e-3)" 12.2 25.9 37.5 10.9 35.1 10.0 11.6 55.0 30.1 47.2 55.4 16.1 6.9 21.7 4.6 12.9 334.8 11.2 13.5 40.2 69.6 38.3 21.5 49.5 12.2 72.6 105.3 13.8 24.0 3.3 27.9 9.3 85.7 40.4 2.8 2.2 24.9 30.9 4.3 16.2 18.7 2.3 60.9 25.2 37.5 6.4 50.0 5.7 30.8 1.1 4.2 44.2 13.7 66.1 2.2 2.3 0.9 6.3 2.1 3.2 4.0 0.7 0.7 0.3 0.6 1.5 13.8 0.9 4.0 1.5 0.7 2.3 0.1 0.6 0.0 4.7 1.9 0.8 4.8 4.7 2.5 0.8 3.5 4.1 4.2 0.4 0.8 4.0 1.0 4.7 0.7 5.4 0.7 4.4 2.4 4.0 0.7 19.4 12.6 3.1 0.3 4.7 1.8 6.2 1.0 4.9 1.0 65.1 6.6 2.0 4.3 4.7 1.5 0.6 0.4 4.6 17.1 19.8 6.5 1.1 7.7 1.8 2.8 0.4 0.7 0.3 1.7 0.6 0.9 0.9 1.0 1.3 0.8 1.8 0.8 0.7 0.7 1.8 0.4 1.5 1.0 0.8 37.5 35.1 55.0 30.1 40.2 69.6 72.6 105.3 85.7 60.9 50.0 66.1 5.3 12.8 16.5 11.1 3.3 4.8 32.1 122.8 1.8 2.5 8.9 8.8 2.2 0.0 161.5 121.4 4.2 24.3 7.4 5.3 35.2 34.7 6.5 2622.9 48.3 5.5 19.2 0.4 2.6 5.9 22.8 12.9 33.6 330.8 6.3 8.1 0.0 0.0 5.2 6.7 3.2 25.1 197.4 0.0 5.9 5.7 4.7 6.6 10.6 6.5 3.0 7.7 9.2 3.5 12.9 36.9 3.3 4.9 3.8 20.4 4.2 4.5 1557.4 4.2 6.6 3.5 42.7 0.4 0.6 0.9 4.1 20.5 9.2 3.3 9.3 128.6 CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.5;Endothelial cells: 42.2;Hepatic stellate cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA071906: AB_2732191, HPA075184: AB_2732281" "unprognostic (1.60e-1)" "unprognostic (4.54e-2)" "unprognostic (9.12e-3)" "unprognostic (5.27e-3)" "unprognostic (9.32e-2)" "unprognostic (5.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-2)" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.47e-5)" "unprognostic (1.82e-2)" "prognostic favorable (4.83e-8)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.95e-2)" 33.8 22.7 19.4 4.9 22.6 0.4 30.0 19.7 18.6 15.1 4.6 16.5 9.0 21.0 2.7 10.8 21.7 11.2 28.2 16.7 17.2 26.9 11.3 42.3 2.9 22.6 21.7 12.0 10.8 9.4 13.6 11.8 18.7 14.9 2.9 4.8 11.5 8.7 15.3 12.7 11.4 10.4 18.1 30.8 15.0 5.6 20.0 2.9 22.6 9.9 1.5 16.0 14.3 23.1 13.3 17.2 10.2 14.4 6.6 4.1 11.2 6.6 8.7 15.8 10.2 19.0 5.6 0.5 7.4 7.7 10.5 12.0 8.2 7.7 3.9 4.7 10.8 9.4 17.2 7.5 7.7 0.5 12.6 3.5 10.4 8.2 5.9 5.3 16.2 13.3 6.9 1.6 5.0 31.1 24.3 0.7 7.5 10.3 17.5 12.8 21.8 2.1 10.2 13.4 10.4 10.2 13.9 18.7 11.0 8.7 13.7 4.0 13.9 16.1 14.6 7.9 8.7 1.2 5.9 1.5 5.6 0.3 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 22.6 19.7 18.6 16.7 17.2 22.6 21.7 18.7 18.1 20.0 23.1 75.5 3.2 2.2 11.1 1.3 8.0 2.5 3.5 6.8 6.5 5.8 5.0 11.4 2.8 1.8 9.2 10.4 2.2 0.6 11.7 3.9 5.1 0.5 2.8 4.4 42.2 7.7 8.0 1.3 5.3 1.9 6.0 8.2 5.7 0.0 14.9 56.7 6.8 2.7 3.3 1.7 4.3 8.2 4.1 3.1 2.3 8.1 1.2 1.8 7.5 2.0 28.2 0.0 15.1 8.3 6.0 6.0 11.3 1.6 2.5 8.4 3.1 1.4 6.8 0.0 5.5 6.4 2.7 4.4 4.5 7.0 2.2 0.5 5.7 4.6 2.2 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 45.7 21.7 7.0 69.4 7.2 48.5 44.4 7.4 12.4 26.4 8.6 27.6 62.4 18.4 33.1 47.7 34.9 50.1 17.8 7.5 8.0 33.3 54.1 61.3 80.2 9.7 8.1 43.2 52.5 4.7 11.0 70.2 8.7 21.7 30.7 2.0 55.2 15.5 7.5 46.7 58.8 32.2 8.3 71.1 42.4 4.9 9.0 57.2 15.6 18.1 82.1 76.5 30.5 8.7 33.8 9.5 0.0 12.9 58.2 140.4 27.8 68.0 103.2 80.5 117.0 22.4 128.5 22.3 123.1 71.5 110.4 52.7 0.0 94.3 78.8 22.4 0.4 53.1 7.4 55.8 158.2 48.5 19.2 122.6 127.0 97.9 144.4 104.7 143.8 0.5 1.3 0.0 64.4 2.8 26.1 46.7 0.0 71.6 28.2 21.4 21.5 14.2 64.9 46.2 0.6 0.4 60.8 31.6 49.3 0.7 11.9 62.5 93.2 84.4 30.4 80.8 40.5 0.0 0.0 0.3 42.2 105.5 63.4 136.4 292.0 50.6 208.9 312.9 224.8 141.9 155.6 193.9 205.5 144.4 93.4 138.5 667.2 226.2 255.4 35.4 257.9 410.9 7.0 7.2 7.4 12.4 7.5 8.0 9.7 8.1 8.7 8.3 9.0 8.7 78.1 60.9 60.8 0.3 87.4 55.8 63.3 130.1 21.1 0.0 40.8 48.4 5.6 47.1 107.0 22.0 0.0 129.1 80.4 12.4 15.6 157.5 0.6 35.9 27.7 73.0 20.9 12.4 0.0 189.9 103.0 53.6 33.1 45.7 34.8 32.6 82.1 34.7 116.7 0.0 0.2 37.8 73.2 168.0 81.2 2.1 29.2 105.2 30.2 23.4 141.5 1.9 177.1 1.5 0.2 148.5 8.6 20.7 50.5 31.1 85.4 41.1 86.1 0.4 6.6 38.1 34.2 0.2 0.5 25.8 45.9 115.9 102.1 36.8 32.9 80.0 CAST ENSG00000153113 Calpastatin P20810 5 96525267-96779595 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 858.4;Early spermatids: 979.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009491, HPA036881, HPA036882, HPA075906" Enhanced Enhanced "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 17000000 "Cluster 27: Non-specific - Gene expression" "Cluster 59: Non-specific - Translation" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "CAB009491: AB_2259755, HPA036881: AB_2675359, HPA036882: AB_2675360, HPA075906: " "unprognostic (2.17e-1)" "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.91e-2)" "unprognostic (4.68e-2)" "unprognostic (1.45e-1)" "unprognostic (3.79e-1)" "unprognostic (4.53e-3)" "unprognostic (1.94e-2)" "unprognostic (6.11e-3)" "prognostic unfavorable (9.27e-5)" "unprognostic (2.66e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.16e-1)" "unprognostic (2.79e-1)" "prognostic unfavorable (4.98e-4)" 144.4 68.4 32.3 86.1 36.3 119.1 104.1 35.0 40.8 147.2 55.5 160.1 120.5 83.8 49.0 342.8 79.7 78.7 303.7 30.7 42.2 82.0 116.8 112.1 52.9 46.7 43.2 83.1 56.1 111.7 51.2 116.1 44.4 100.2 148.2 17.1 130.0 78.7 317.3 157.4 137.2 92.2 38.3 64.1 100.5 98.8 39.1 43.1 97.9 166.4 104.3 129.4 216.4 41.7 300.3 239.7 42.6 112.1 240.1 390.1 145.4 220.9 288.8 169.1 215.8 60.4 189.6 44.1 189.8 286.1 263.1 465.6 81.3 283.5 202.8 292.4 78.5 65.9 251.0 71.1 172.9 38.9 100.1 201.8 254.8 239.6 375.0 222.9 194.8 33.5 51.7 144.5 196.4 98.0 17.9 2.0 35.4 85.0 89.9 18.2 141.9 78.3 327.1 114.1 179.6 45.0 222.6 118.2 142.5 94.0 77.4 39.5 263.9 239.0 94.6 154.9 211.4 51.2 140.4 22.1 264.7 21.8 67.5 10.5 156.6 24.1 75.6 85.3 74.1 79.4 68.2 76.9 107.5 79.1 34.8 45.7 38.2 61.6 109.8 28.8 79.2 108.1 32.3 36.3 35.0 40.8 30.7 42.2 46.7 43.2 44.4 38.3 39.1 41.7 251.6 403.8 221.4 58.1 153.8 239.6 439.8 223.6 169.0 39.4 133.6 84.5 858.4 163.0 277.0 108.5 18.8 181.2 227.1 484.0 133.1 263.6 979.7 348.0 213.4 188.5 142.1 229.3 60.2 249.7 96.2 259.0 153.4 327.8 177.1 71.8 138.8 169.3 113.7 13.5 53.0 253.9 103.7 209.4 259.1 414.4 172.1 243.8 131.6 63.7 354.4 36.9 293.6 33.2 70.2 325.1 346.8 146.3 126.3 314.7 302.9 152.3 379.0 19.5 92.1 267.8 175.0 23.6 17.9 348.9 251.7 140.8 207.7 69.8 221.2 548.5 CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 182.7;tongue: 72.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 22.9;Early spermatids: 4.2;Sertoli cells: 6.6;Skeletal myocytes: 11.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017518, CAB018557, HPA054488" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 5.7 0.1 0.1 27.4 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 2.5 0.2 182.7 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.1 72.8 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 11.0 2.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CAVIN3 "cavin-3, HSRBC, MGC20400, PRKCDBP, SRBC" ENSG00000170955 "Caveolae associated protein 3" Q969G5 11 6318946-6320532 "Predicted intracellular proteins" "Biological rhythms" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 140.5;Exocrine glandular cells: 252.2;Extravillous trophoblasts: 88.9;Fibroblasts: 88.7;Pancreatic endocrine cells: 219.0;Smooth muscle cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 16.2;myeloid DC: 42.8" "Group enriched" "Detected in many" 5 "dendritic cells: 42.8;monocytes: 16.2" "Cell line enhanced" "Detected in many" "A-431: 120.7;BJ: 111.6;HaCaT: 91.7;TIME: 133.6;U-87 MG: 125.9;WM-115: 137.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055136, HPA073327" Supported Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA055136: AB_2682711, HPA073327: AB_2686595" "unprognostic (7.92e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.12e-2)" "unprognostic (2.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.69e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.37e-1)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.21e-6)" "unprognostic (3.85e-2)" "unprognostic (1.70e-1)" "unprognostic (1.62e-1)" "unprognostic (1.96e-2)" 69.3 20.3 5.0 16.4 5.3 0.5 51.7 4.9 7.3 73.5 10.3 69.8 5.8 106.5 1.3 19.2 48.8 1.3 57.9 4.3 4.3 24.9 8.3 37.8 2.5 5.1 4.3 37.0 21.4 1.3 8.1 11.7 5.4 43.6 4.0 0.0 20.3 13.1 17.1 28.3 29.6 22.9 4.9 25.0 37.3 12.1 5.7 1.1 22.6 5.6 1.4 79.3 58.2 4.1 120.7 12.1 0.1 0.4 5.4 24.7 0.0 111.6 45.1 18.5 20.5 0.0 0.1 0.0 36.6 26.1 1.9 91.7 0.0 9.0 3.4 30.1 0.0 0.0 14.0 0.0 14.6 0.0 0.5 16.6 12.4 6.9 9.0 0.0 35.7 0.0 0.0 0.7 19.8 0.0 0.0 0.1 74.6 0.9 2.0 0.0 0.0 0.2 25.6 0.0 0.0 0.1 40.9 0.2 27.0 0.7 0.2 0.5 133.6 0.0 0.4 46.0 0.4 0.2 1.0 0.2 125.9 0.0 137.7 0.0 16.2 0.0 0.0 1.1 0.0 0.0 0.8 0.0 42.8 0.0 0.0 0.0 0.2 0.4 0.0 0.0 6.1 5.9 5.0 5.3 4.9 7.3 4.3 4.3 5.1 4.3 5.4 4.9 5.7 4.1 140.5 12.8 6.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 7.7 36.2 0.0 0.0 8.1 16.5 0.0 3.6 1.0 0.0 39.2 6.0 0.0 6.9 59.7 70.3 0.0 0.0 0.0 252.2 88.9 88.7 0.0 8.0 0.0 2.6 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 30.5 0.0 0.0 0.0 0.0 219.0 0.0 0.0 0.5 0.0 0.0 47.6 10.2 0.0 0.0 0.0 146.0 0.0 0.0 0.0 0.0 8.5 1.6 45.7 0.0 0.0 CAVIN4 "cavin-4, MURC" ENSG00000170681 "Caveolae associated protein 4" Q5BKX8 9 100578079-100588389 "Predicted intracellular proteins" "Differentiation, Myogenesis, Transcription, Transcription regulation" "Activator, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "skeletal muscle: 276.1;tongue: 92.4" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.5;Endometrial ciliated cells: 1.2;Endometrial stromal cells: 1.8;Glandular and luminal cells: 1.9;Granulosa cells: 1.8;Pancreatic endocrine cells: 1.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "NTERA-2: 8.9;SCLC-21H: 13.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020973, HPA020987, HPA021021" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA020973: AB_1853079, HPA020987: AB_1853080, HPA021021: AB_1853082" "unprognostic (9.54e-5)" "unprognostic (1.68e-2)" "unprognostic (2.50e-2)" "unprognostic (3.76e-2)" "unprognostic (4.92e-2)" "unprognostic (4.56e-3)" "unprognostic (1.14e-4)" "unprognostic (3.36e-2)" "unprognostic (2.23e-1)" "unprognostic (1.60e-1)" "unprognostic (1.31e-1)" "unprognostic (4.02e-1)" "unprognostic (1.74e-8)" "unprognostic (1.14e-1)" "unprognostic (3.39e-1)" "unprognostic (3.68e-3)" "unprognostic (1.55e-3)" 0.2 0.1 1.6 0.2 2.9 0.1 0.1 2.0 5.6 0.4 0.4 0.4 0.0 0.5 0.1 4.3 0.1 0.3 45.9 1.7 2.5 0.2 0.2 0.4 0.1 2.7 2.7 0.2 0.1 0.0 0.2 0.3 2.7 4.5 0.1 0.3 2.4 0.1 276.1 0.2 0.1 0.3 1.8 0.1 0.3 3.7 2.7 0.4 0.5 92.4 0.1 0.3 0.2 3.5 0.5 0.3 6.1 2.2 1.4 2.0 4.3 1.1 0.9 0.8 1.0 0.0 0.4 0.2 0.3 0.6 2.1 0.3 3.1 0.1 1.7 1.4 2.0 0.1 1.0 0.0 0.4 0.2 0.4 5.0 0.3 0.8 0.5 1.5 1.1 1.5 0.2 0.2 3.9 0.1 1.8 0.3 8.9 1.0 0.7 2.6 5.8 0.0 0.8 0.3 13.2 3.4 0.2 0.2 1.1 4.1 0.1 0.2 1.1 1.5 1.2 1.0 1.0 0.3 1.1 0.6 1.7 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.9 2.0 5.6 1.7 2.5 2.7 2.7 2.7 1.8 2.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.7 0.0 1.2 1.8 0.3 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.9 0.0 1.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 CBWD1 ENSG00000172785 "COBW domain containing 1" Q9BRT8 9 121038-179147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 185.1" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (3.75e-2)" "unprognostic (3.47e-2)" "unprognostic (5.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.39e-1)" "unprognostic (2.67e-2)" "unprognostic (3.91e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (2.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.68e-2)" "unprognostic (5.80e-7)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (8.94e-2)" "unprognostic (4.98e-3)" 18.6 34.4 8.7 15.3 9.2 13.0 19.9 10.6 11.1 14.3 13.0 16.9 13.3 13.7 20.8 26.8 14.6 10.6 20.7 9.0 10.2 40.1 26.8 16.1 13.4 9.0 9.0 15.4 30.0 38.3 19.4 22.2 9.2 19.9 15.2 27.5 23.7 12.2 21.8 22.3 14.1 12.2 9.0 16.9 19.1 16.4 9.1 13.2 25.4 17.6 20.1 23.4 17.1 9.9 43.3 16.1 22.7 12.2 29.1 26.2 50.3 22.2 14.6 30.4 23.0 23.4 16.1 39.4 28.3 8.2 18.4 7.3 11.3 21.1 32.4 67.8 38.9 0.4 39.1 72.6 31.5 115.1 17.2 23.5 9.9 7.3 59.0 19.5 32.9 19.7 13.6 84.3 25.2 52.1 25.1 185.1 22.9 37.6 34.6 47.7 34.6 75.8 39.4 120.7 40.8 24.8 45.8 16.8 17.8 55.5 35.6 109.2 34.4 16.0 22.9 20.8 19.7 10.1 14.6 44.6 39.6 60.6 19.2 3.6 65.7 19.3 10.3 75.6 16.9 21.1 18.6 16.8 74.1 15.7 16.2 17.7 10.2 12.8 60.8 19.6 18.1 48.3 8.7 9.2 10.6 11.1 9.0 10.2 9.0 9.0 9.2 9.0 9.1 9.9 19.5 54.5 50.1 8.1 41.2 47.7 29.9 47.6 97.9 50.8 49.4 37.6 51.8 30.0 49.8 35.0 108.4 96.3 17.7 20.4 35.2 79.9 51.7 14.9 10.1 23.0 31.2 44.6 17.0 118.5 41.2 23.0 34.7 11.9 32.8 26.7 20.7 19.0 32.0 38.7 17.1 39.0 50.8 25.1 38.0 16.4 18.0 37.9 32.0 18.7 81.5 32.2 18.6 5.5 16.7 66.9 38.2 13.2 90.0 32.0 49.5 73.6 31.0 63.5 32.9 20.2 27.8 48.6 28.1 83.8 50.6 124.8 23.5 24.1 62.3 24.9 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 CBWD3 bA561O23.1 ENSG00000196873 "COBW domain containing 3" Q5JTY5 9 68232003-68300035 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Uncertain Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (1.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.95e-1)" "unprognostic (9.71e-3)" "unprognostic (9.99e-2)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.05e-2)" "unprognostic (2.05e-2)" "unprognostic (1.05e-3)" "unprognostic (3.77e-2)" "unprognostic (1.67e-1)" "unprognostic (4.43e-3)" "unprognostic (5.16e-4)" 12.2 19.4 7.5 18.8 7.5 13.5 17.3 9.8 9.5 9.8 5.3 14.0 13.0 9.9 7.3 17.2 9.7 6.6 13.0 8.1 8.9 21.2 28.4 10.2 16.9 8.4 7.7 12.0 27.2 8.6 18.4 15.6 8.8 10.5 9.8 18.0 13.5 10.2 17.5 13.1 20.6 8.9 4.4 12.7 17.5 12.3 6.9 12.7 14.3 13.3 13.0 18.8 12.2 10.6 73.0 52.6 25.1 41.2 18.9 6.7 34.3 35.6 14.1 15.2 17.4 15.0 69.4 84.1 33.9 26.1 67.5 86.7 48.0 70.5 39.8 128.2 31.0 31.9 137.8 73.6 24.8 60.9 38.3 15.6 21.3 27.0 35.3 30.5 35.6 93.1 60.4 66.1 22.3 47.4 71.8 81.9 38.5 86.4 88.7 32.6 78.7 94.0 17.3 32.8 40.3 25.7 58.0 36.2 46.3 46.6 26.7 71.5 16.6 22.6 58.1 38.4 70.1 38.3 165.4 102.3 68.8 92.3 41.6 29.8 86.1 66.2 27.8 71.5 24.0 52.5 25.2 28.7 62.0 52.3 27.6 25.5 86.5 16.1 52.0 46.5 37.9 59.8 7.5 7.5 9.8 9.5 8.1 8.9 8.4 7.7 8.8 4.4 6.9 10.6 4.3 25.6 30.0 2.0 15.9 14.5 16.2 6.0 12.0 25.2 14.5 9.7 28.7 7.2 21.0 11.0 29.2 13.2 5.6 9.7 1.9 7.1 4.7 4.0 2.4 9.0 4.2 5.2 10.8 11.6 7.9 8.9 8.6 3.8 12.6 12.4 6.1 8.2 5.0 11.8 8.9 9.1 2.0 11.0 10.1 2.4 5.0 6.8 5.4 6.5 19.7 5.9 8.2 10.1 5.6 8.8 17.4 3.0 20.3 12.6 28.9 7.1 24.1 36.2 6.6 5.3 6.3 16.7 7.8 7.3 21.5 15.5 10.6 7.6 10.7 12.9 CBWD5 ENSG00000147996 "COBW domain containing 5" Q5RIA9 9 65668805-65734041 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 178.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (8.18e-2)" "unprognostic (4.23e-3)" "unprognostic (5.25e-3)" "unprognostic (1.02e-3)" "unprognostic (5.32e-3)" "unprognostic (9.24e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-2)" "unprognostic (1.11e-2)" "unprognostic (6.46e-3)" "unprognostic (1.03e-1)" "unprognostic (4.61e-3)" "unprognostic (1.17e-1)" "unprognostic (5.68e-2)" "unprognostic (3.87e-1)" 9.8 15.2 20.7 8.4 21.1 7.0 17.0 21.7 25.8 11.2 20.6 11.4 11.0 6.5 9.0 15.5 10.9 5.2 12.5 21.1 22.3 26.0 41.9 9.6 6.6 21.1 21.3 10.6 19.4 7.8 16.8 6.7 21.5 17.4 10.5 8.7 9.6 7.7 8.4 11.0 13.9 5.9 20.7 21.2 11.4 11.4 21.0 4.6 15.6 4.2 9.7 12.7 9.8 21.8 37.7 40.1 14.0 17.3 20.8 9.5 16.4 26.0 17.6 20.2 20.6 5.2 33.6 51.2 16.2 15.3 29.1 27.2 64.1 21.3 38.2 8.4 15.4 14.4 69.3 91.0 16.2 32.8 8.9 16.9 23.9 18.7 14.8 25.0 37.3 19.4 20.5 36.9 21.1 45.8 16.4 34.2 16.3 64.4 42.4 28.1 19.2 49.9 32.4 23.9 18.1 18.3 21.2 16.1 8.0 24.5 76.4 21.3 10.6 9.1 33.6 27.7 30.2 12.0 34.8 11.8 37.4 35.9 35.3 1.7 11.8 8.8 3.2 15.0 3.7 5.3 5.3 4.6 12.4 3.0 4.8 4.0 7.8 2.8 9.8 5.2 4.4 10.6 20.7 21.1 21.7 25.8 21.1 22.3 21.1 21.3 21.5 20.7 21.0 21.8 17.8 41.7 51.8 13.4 58.4 65.1 31.8 24.6 178.7 37.7 59.4 36.7 33.6 25.8 38.5 20.2 68.8 44.0 10.6 33.2 21.5 33.1 10.5 17.4 8.4 22.8 16.8 25.9 60.6 39.0 23.0 20.1 49.5 15.4 10.1 16.3 16.4 48.0 15.9 35.3 60.8 32.6 12.2 25.1 36.6 4.6 21.1 27.5 30.2 20.6 45.2 13.5 7.2 37.2 32.2 33.7 51.1 17.3 143.5 32.3 76.9 42.7 27.8 62.4 6.6 10.4 18.8 35.2 25.5 119.4 85.5 50.5 29.6 12.3 34.2 30.5 CBWD6 CBWD7 ENSG00000215126 "COBW domain containing 6" Q4V339 9 41131306-41199261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.4;Excitatory neurons: 24.9;Inhibitory neurons: 20.2;Langerhans cells: 30.0;Oligodendrocyte precursor cells: 18.6;Suprabasal keratinocytes: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 17.3;PC-3: 26.8;TIME: 16.6" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (9.48e-2)" "unprognostic (6.02e-2)" "unprognostic (1.62e-2)" "unprognostic (1.91e-2)" "unprognostic (1.30e-2)" "unprognostic (6.28e-2)" "unprognostic (5.92e-2)" "unprognostic (3.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.24e-2)" "unprognostic (1.09e-1)" "unprognostic (2.28e-4)" "unprognostic (5.65e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (9.94e-4)" 2.0 5.3 1.8 0.7 1.8 2.2 2.1 1.8 3.4 1.0 2.5 1.9 1.1 1.2 0.2 2.9 0.9 1.5 3.4 1.8 2.1 3.4 7.2 2.0 0.3 1.9 1.9 1.6 3.4 0.1 2.7 0.2 2.2 1.7 0.1 0.9 2.5 1.9 3.6 1.5 1.9 0.3 1.9 2.1 2.2 1.9 2.0 0.1 2.2 0.0 0.5 1.1 1.9 1.8 2.0 0.5 0.9 0.2 0.9 2.4 1.6 11.0 12.4 12.6 0.0 4.3 1.2 2.7 0.5 9.0 0.5 1.8 15.9 0.3 0.4 2.8 10.6 0.7 6.4 2.9 0.1 3.4 1.0 0.2 1.5 8.4 10.1 0.9 9.7 0.8 1.4 1.5 17.3 1.8 5.1 0.7 2.3 4.5 26.8 1.2 10.8 3.6 11.5 0.5 0.7 1.2 2.7 0.8 1.1 2.2 0.9 1.5 16.6 0.2 1.0 0.3 1.2 4.9 0.8 13.5 1.5 1.0 1.2 1.6 4.1 1.7 0.6 5.0 0.9 3.5 2.9 2.3 2.3 1.2 1.8 2.2 0.6 0.4 7.0 2.7 1.3 2.4 1.8 1.8 1.8 3.4 1.8 2.1 1.9 1.9 2.2 1.9 2.0 1.8 2.0 3.2 8.9 5.2 1.3 39.4 0.0 11.0 0.0 0.0 5.1 2.7 0.0 0.0 7.5 5.5 0.0 5.2 1.4 0.0 3.9 4.3 0.0 1.5 0.9 1.4 0.0 0.0 24.9 4.9 5.2 1.4 0.0 1.4 8.8 2.2 0.0 0.0 3.0 0.0 20.2 0.0 8.2 0.0 30.0 0.0 0.0 1.4 14.2 5.6 1.6 0.0 0.0 18.6 8.1 4.4 0.0 0.0 1.4 0.0 0.0 8.8 7.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 42.9 6.3 2.8 1.4 0.0 0.0 CBY2 "NURIT, SPERT" ENSG00000174015 "Chibby family member 2" Q8NA61 13 45702320-45714559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 441 "testis: 99.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039359, HPA040046" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 36: Testis - Spermatogenesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cell Junctions" "HPA039359: AB_10794088, HPA040046: AB_10796117" "unprognostic (2.86e-1)" "unprognostic (3.38e-1)" "unprognostic (1.64e-2)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (4.19e-4)" "unprognostic (8.52e-2)" "unprognostic (8.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.38e-1)" "unprognostic (2.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.56e-2)" "unprognostic (1.97e-2)" "unprognostic (4.15e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 99.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CC2D1A "FLJ20241, Freud-1, MRT3" ENSG00000132024 "Coiled-coil and C2 domain containing 1A" Q6P1N0 19 13906201-13930879 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005436, CAB015220" Supported Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli fibrillar center" "CAB015220: , HPA005436: AB_1078884" "unprognostic (8.66e-2)" "unprognostic (1.31e-2)" "unprognostic (2.55e-1)" "unprognostic (2.34e-1)" "unprognostic (1.07e-1)" "prognostic favorable (7.02e-4)" "unprognostic (7.00e-2)" "unprognostic (1.59e-3)" "unprognostic (1.17e-1)" "unprognostic (2.82e-2)" "unprognostic (2.61e-3)" "unprognostic (4.07e-2)" "unprognostic (1.23e-3)" "unprognostic (6.67e-3)" "unprognostic (1.97e-1)" "unprognostic (9.22e-2)" "unprognostic (1.71e-2)" 16.8 16.4 11.6 3.8 11.3 3.7 21.3 10.1 18.1 19.4 10.3 37.4 16.2 16.2 2.1 33.3 19.8 2.9 20.5 11.8 11.9 22.9 26.9 16.0 3.2 11.3 11.4 18.7 34.3 7.9 31.8 3.1 11.8 25.8 4.7 4.1 27.4 5.2 28.3 35.5 33.1 3.4 9.8 17.7 24.7 15.9 13.2 2.6 20.6 3.9 3.1 21.2 24.8 10.8 22.0 8.5 2.3 9.9 5.1 3.1 9.3 6.9 8.1 10.2 10.4 14.5 6.8 11.2 11.4 6.1 6.4 15.2 5.3 10.1 3.3 17.0 30.9 5.2 11.0 6.9 9.0 4.1 15.2 4.7 12.5 7.2 4.3 6.5 7.2 11.5 6.4 8.5 3.4 22.4 11.6 12.1 7.1 18.5 16.7 11.2 6.3 8.9 6.5 16.3 10.2 7.1 9.8 13.3 12.2 1.6 10.4 9.8 6.3 8.3 4.4 20.9 8.9 15.2 7.3 6.6 10.8 14.3 7.8 0.5 0.3 0.8 0.4 0.7 0.1 0.2 0.2 0.2 0.4 0.1 0.0 0.2 0.1 0.2 0.5 0.3 0.3 0.3 11.6 11.3 10.1 18.1 11.8 11.9 11.3 11.4 11.8 9.8 13.2 10.8 20.6 9.6 8.3 23.8 12.6 9.1 14.2 15.6 19.4 66.6 19.2 64.6 8.4 21.5 16.5 11.0 93.8 22.3 11.7 103.4 9.8 22.0 2.2 10.1 6.7 13.2 33.5 18.7 38.4 27.7 10.7 10.5 63.7 11.3 17.7 29.3 12.8 12.4 14.5 30.3 43.3 46.6 24.4 12.2 13.0 6.5 64.3 11.3 7.2 10.3 16.3 15.6 23.7 31.2 24.1 26.0 77.6 87.3 12.3 13.0 97.9 6.8 16.7 93.2 13.1 8.0 9.3 10.2 12.4 24.8 13.8 21.3 14.8 16.1 64.3 18.8 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC107 MGC31967 ENSG00000159884 "Coiled-coil domain containing 107" Q8WV48 9 35658290-35661511 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016857, HPA050442" Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA016857: AB_10669751, HPA050442: AB_2681128" "unprognostic (3.70e-3)" "unprognostic (7.07e-3)" "unprognostic (3.60e-2)" "unprognostic (2.63e-2)" "unprognostic (7.77e-2)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.09e-2)" "unprognostic (4.13e-1)" "unprognostic (1.72e-2)" "unprognostic (1.32e-2)" "unprognostic (1.26e-1)" "unprognostic (8.33e-2)" "unprognostic (1.89e-1)" "unprognostic (5.15e-1)" "unprognostic (1.96e-1)" "unprognostic (5.75e-2)" 91.6 61.0 35.1 19.1 34.6 7.8 75.3 37.4 40.6 48.5 36.0 117.8 19.2 74.2 31.1 25.1 60.6 15.3 90.3 34.5 35.3 37.7 50.3 43.6 15.4 35.5 35.7 32.3 62.7 12.8 33.0 13.9 36.0 55.9 16.8 13.9 26.6 29.2 64.4 32.5 47.1 28.2 34.7 41.2 74.4 17.1 37.3 26.0 31.4 22.4 14.4 76.6 39.1 35.0 17.9 15.7 12.8 16.3 63.3 40.3 7.4 29.5 26.4 18.5 17.2 7.2 5.2 11.5 12.8 38.9 47.6 5.9 9.6 14.2 13.6 34.4 15.3 5.5 25.1 18.3 15.0 8.5 20.1 24.1 16.6 19.8 15.3 34.4 13.1 19.2 7.2 21.7 23.4 11.6 9.5 12.6 9.5 12.6 48.2 13.7 2.9 9.3 62.8 9.6 8.4 14.0 15.2 21.1 15.4 9.5 11.1 10.4 16.7 29.5 16.3 21.6 27.3 9.6 15.4 23.1 54.6 13.5 26.2 33.3 39.3 20.1 128.7 43.2 168.8 79.5 111.6 113.8 45.0 79.5 53.2 74.2 7.8 69.3 25.9 123.8 140.8 75.1 35.1 34.6 37.4 40.6 34.5 35.3 35.5 35.7 36.0 34.7 37.3 35.0 68.7 67.3 25.0 11.1 104.8 70.2 38.0 76.9 8.6 31.9 39.2 65.3 0.7 60.1 48.4 82.8 8.4 15.0 175.2 143.9 17.6 74.1 7.6 33.5 34.1 36.1 88.1 15.8 8.6 140.2 66.2 60.0 121.8 30.5 34.3 24.4 53.9 77.3 90.9 32.0 10.2 100.5 69.2 46.9 185.9 28.3 59.4 82.0 113.8 13.1 43.5 57.2 133.9 7.5 10.8 86.7 108.6 102.3 53.3 45.3 146.7 66.9 48.2 34.1 118.3 33.7 135.3 37.9 63.1 17.8 66.9 13.8 132.7 44.9 51.7 29.5 CCDC112 MGC39633 ENSG00000164221 "Coiled-coil domain containing 112" Q8NEF3 5 115267190-115296693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 40.7" "Cell type enhanced" "Detected in many" "Spermatocytes: 201.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 113.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045120, HPA050621" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 25: RPMI-8226 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA045120: AB_2679222, HPA050621: AB_2681191" "unprognostic (1.88e-2)" "unprognostic (5.10e-2)" "unprognostic (4.63e-2)" "unprognostic (5.60e-3)" "unprognostic (2.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.32e-6)" "unprognostic (4.30e-2)" "unprognostic (3.24e-1)" "unprognostic (4.41e-2)" "unprognostic (3.33e-1)" "unprognostic (2.64e-1)" "prognostic unfavorable (1.51e-6)" "unprognostic (7.00e-2)" "unprognostic (2.79e-2)" "unprognostic (8.61e-2)" "unprognostic (4.10e-3)" 4.3 3.6 5.7 5.3 6.3 7.3 6.0 7.4 7.3 4.5 2.6 9.1 7.2 5.6 6.2 4.5 4.1 3.1 6.0 5.8 6.6 2.8 1.2 5.5 4.6 6.4 5.5 2.1 10.2 4.5 4.6 2.4 6.3 6.7 9.3 7.9 6.5 5.0 4.3 4.9 6.3 5.4 5.7 4.6 6.4 40.7 5.9 3.7 4.0 2.5 4.2 3.8 3.6 7.8 12.0 5.9 11.5 18.5 7.1 14.0 2.9 10.5 5.3 7.7 8.7 2.6 6.7 14.8 8.9 7.2 11.4 7.5 12.1 6.0 16.0 12.0 10.1 9.8 8.8 3.8 9.7 12.9 4.8 6.4 7.2 9.8 13.0 8.8 12.1 13.1 4.1 11.6 10.8 9.3 19.2 11.4 13.1 11.0 11.0 20.6 14.5 113.7 7.7 4.2 17.9 23.5 11.5 7.2 32.8 7.8 12.2 18.9 12.6 10.1 6.9 19.7 14.8 13.2 13.2 3.0 6.7 9.9 6.0 0.3 5.0 11.0 2.9 4.0 3.3 2.8 2.2 2.5 5.4 4.0 2.8 1.9 3.2 3.0 4.9 10.2 0.1 2.1 5.7 6.3 7.4 7.3 5.8 6.6 6.4 5.5 6.3 5.7 5.9 7.8 15.7 16.0 14.0 16.0 19.2 14.1 5.0 6.0 8.0 29.2 19.4 18.4 17.6 8.6 8.4 5.5 10.4 0.7 19.5 23.6 5.9 28.2 8.5 23.0 21.4 12.4 40.6 20.8 26.4 25.9 2.0 11.5 14.3 12.3 9.5 15.0 7.9 3.1 32.7 10.1 15.2 33.4 6.1 28.6 31.5 18.5 4.1 31.5 14.2 15.0 36.6 11.0 11.3 21.1 54.7 27.1 18.7 4.1 27.3 8.0 11.8 4.4 11.7 24.9 13.1 18.5 18.2 201.8 73.3 13.8 22.6 0.5 9.2 5.5 32.8 3.4 CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Vesicles "HPA034598: AB_10601697" "prognostic favorable (7.59e-4)" "unprognostic (1.28e-2)" "unprognostic (1.10e-3)" "unprognostic (6.80e-3)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (8.13e-3)" "unprognostic (2.63e-1)" "unprognostic (4.29e-1)" "unprognostic (2.87e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-2)" "unprognostic (2.16e-1)" "unprognostic (3.16e-2)" 27.8 25.1 25.3 18.0 25.8 24.8 25.4 26.4 28.0 33.7 21.7 25.3 21.2 29.5 32.3 31.1 29.9 19.9 18.4 25.2 26.6 29.8 17.8 26.6 29.8 26.8 25.3 41.6 20.2 40.2 22.9 13.8 26.3 24.0 19.3 15.8 29.1 27.7 12.9 39.3 24.2 17.7 26.1 26.1 24.1 10.4 25.4 23.3 30.3 12.3 26.0 26.8 28.1 27.5 22.5 10.5 13.3 8.1 27.2 30.7 16.3 10.5 28.2 22.4 26.1 24.4 48.5 25.7 36.6 18.3 11.4 20.7 10.8 19.2 16.1 33.4 20.2 20.2 5.4 27.3 22.7 20.8 40.2 26.2 44.2 14.6 8.1 21.8 23.7 24.3 19.8 22.6 27.7 20.7 38.5 37.5 17.2 11.2 26.4 29.4 14.2 24.1 18.8 18.6 12.4 22.8 12.3 22.4 24.2 8.7 24.5 25.3 18.6 10.1 10.4 18.5 8.3 12.4 13.0 19.7 22.9 22.1 13.5 129.9 94.6 154.8 80.8 136.0 71.8 96.3 85.1 85.8 95.2 98.9 81.1 74.8 33.3 80.6 174.9 73.8 103.6 132.8 25.3 25.8 26.4 28.0 25.2 26.6 26.8 25.3 26.3 26.1 25.4 27.5 37.5 19.2 28.3 3.6 43.6 51.9 42.3 104.2 40.5 25.9 43.3 41.9 13.9 35.8 50.8 77.3 10.4 76.7 35.1 29.9 105.7 47.4 1.4 14.5 16.9 30.8 27.6 13.5 8.7 42.7 36.6 30.6 21.4 20.3 53.3 22.7 33.2 21.4 63.5 23.5 12.3 35.6 99.7 45.5 60.7 4.5 42.6 49.4 53.4 5.6 97.3 48.4 49.4 10.1 12.2 27.5 49.1 52.3 16.9 14.9 51.9 65.9 24.3 27.6 46.0 29.2 31.7 9.0 24.0 42.4 70.0 26.4 51.3 39.1 41.6 30.0 CCDC124 ENSG00000007080 "Coiled-coil domain containing 124" Q96CT7 19 17933015-17943991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041708, HPA046765" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA041708: AB_2677628, HPA046765: AB_2679793" "unprognostic (9.39e-2)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.32e-2)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-2)" "unprognostic (3.22e-1)" 82.9 67.6 62.4 32.0 62.9 42.7 78.0 64.1 104.5 77.3 54.0 115.7 25.6 78.6 7.1 100.3 67.8 11.2 131.9 61.9 60.7 88.5 88.0 70.8 22.7 63.2 62.1 64.9 72.2 22.1 55.7 20.3 64.8 77.9 8.4 9.0 69.3 22.2 210.2 92.8 58.5 14.2 57.3 67.5 81.2 48.5 66.0 17.7 65.6 38.3 12.2 84.5 80.9 68.2 242.7 165.3 54.2 111.3 35.4 26.9 178.8 118.9 36.7 59.0 49.8 125.0 97.1 182.8 166.7 47.5 38.8 90.1 60.0 108.3 17.2 194.7 341.8 152.7 140.5 147.0 68.4 174.4 100.6 43.2 70.7 59.7 56.9 33.9 62.7 115.0 196.3 74.4 30.8 232.8 166.1 212.3 126.3 79.2 282.2 163.2 103.6 195.1 48.9 85.7 108.6 155.8 83.4 92.4 121.3 22.0 86.2 62.6 142.0 102.3 128.1 198.0 185.6 102.8 121.7 178.5 128.6 203.1 133.0 81.1 82.2 73.5 85.9 95.1 69.2 61.0 66.8 80.8 85.5 66.4 51.8 63.5 20.5 76.3 71.3 75.4 84.1 66.2 62.4 62.9 64.1 104.5 61.9 60.7 63.2 62.1 64.8 57.3 66.0 68.2 58.8 19.2 4.8 8.1 41.1 90.5 60.0 115.9 44.9 22.9 49.3 57.3 15.6 35.8 58.7 73.5 2.1 93.8 44.1 108.9 137.0 146.2 33.4 46.7 50.9 57.3 61.0 79.8 7.4 199.0 140.2 58.1 79.0 56.5 27.3 73.9 50.7 57.1 110.3 10.1 6.4 89.0 101.7 60.0 73.2 106.1 32.6 50.3 96.0 4.7 86.4 50.9 50.4 4.5 7.1 227.9 70.0 41.3 68.7 108.7 78.5 142.3 44.8 23.1 19.7 43.4 76.0 30.9 39.9 79.6 109.8 82.8 42.8 184.7 88.6 73.5 CCDC136 "DKFZP434G156, KIAA1793, NAG6" ENSG00000128596 "Coiled-coil domain containing 136" Q96JN2 7 128790757-128822132 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Fertilization, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 87.6;retina: 52.5;testis: 185.7" "Group enriched" "Detected in many" 4 "Early spermatids: 780.2;Late spermatids: 2032.0" "Cancer enhanced" "Detected in many" "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-87 MG: 30.5;U-937: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010646, HPA071015" Enhanced Approved Approved "Nuclear membrane,Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Vesicles" "Nuclear membrane, Plasma membrane" "HPA010646: , HPA071015: AB_2686334" "unprognostic (2.07e-2)" "unprognostic (2.32e-2)" "unprognostic (1.29e-4)" "unprognostic (4.65e-2)" "unprognostic (4.52e-1)" "unprognostic (2.16e-1)" "unprognostic (1.66e-2)" "unprognostic (2.53e-1)" "unprognostic (5.43e-4)" "unprognostic (2.58e-2)" "unprognostic (8.44e-3)" "unprognostic (4.35e-1)" "unprognostic (1.18e-4)" "unprognostic (5.27e-3)" "unprognostic (4.85e-2)" "unprognostic (1.19e-1)" "unprognostic (8.93e-3)" 1.8 3.7 37.2 1.9 24.4 0.8 1.7 42.7 39.9 5.2 6.2 20.1 1.6 9.3 2.2 1.7 3.3 2.2 5.7 24.2 34.7 0.7 0.3 1.1 2.7 30.5 54.2 2.8 0.8 1.6 6.4 1.4 26.3 12.1 3.1 52.5 1.6 13.6 4.4 0.9 4.8 11.6 34.9 1.5 4.6 185.7 87.6 5.2 1.3 4.0 1.7 13.1 3.9 30.6 1.1 1.5 11.7 7.9 6.3 5.4 2.0 4.7 6.0 4.6 4.3 1.8 1.0 6.5 0.5 6.2 18.4 2.5 7.8 0.9 4.3 17.2 7.7 10.7 3.1 0.0 2.2 1.5 22.2 6.0 0.8 5.0 0.4 4.1 2.7 10.0 4.0 6.0 1.9 2.3 8.0 3.4 16.3 0.1 5.1 19.5 2.3 2.9 0.3 2.4 7.4 20.4 2.9 3.3 5.1 4.1 0.3 3.1 2.4 7.4 4.2 3.7 3.5 3.4 1.6 6.1 30.5 46.2 1.9 0.0 0.0 0.3 0.3 0.0 0.3 0.0 0.3 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 37.2 24.4 42.7 39.9 24.2 34.7 30.5 54.2 26.3 34.9 87.6 30.6 1.6 0.0 0.5 11.4 1.1 0.5 0.9 0.1 1.8 306.0 0.6 3.8 7.5 1.5 0.7 0.0 98.0 0.1 2.2 0.0 0.0 0.7 780.2 0.3 2.2 2.0 0.0 0.4 23.3 1.5 0.3 2.6 1.5 0.1 0.0 1.9 1.1 0.0 6.8 40.4 48.0 0.1 0.0 0.6 1.6 2032.0 18.0 2.3 0.0 10.3 0.7 22.5 2.1 28.6 13.3 0.6 0.1 7.5 1.1 0.9 0.0 0.2 2.0 20.7 6.6 1.6 6.1 321.9 17.2 0.1 0.4 0.4 3.4 0.3 0.0 0.3 CCDC15 FLJ13215 ENSG00000149548 "Coiled-coil domain containing 15" Q0P6D6 11 124954121-125041489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.5" "Group enriched" "Detected in many" 5 "Early spermatids: 42.8;Erythroid cells: 26.3;Late spermatids: 25.8;Spermatocytes: 99.7;Spermatogonia: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040450, HPA041738" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Cytosol "HPA040450: AB_10794031, HPA041738: AB_10794675" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (8.81e-2)" "unprognostic (1.85e-1)" "unprognostic (2.50e-1)" "unprognostic (4.59e-4)" "unprognostic (2.12e-3)" "unprognostic (1.43e-1)" "unprognostic (1.46e-2)" "unprognostic (2.04e-2)" "unprognostic (9.05e-3)" "unprognostic (3.25e-2)" "unprognostic (9.38e-3)" "unprognostic (1.33e-2)" "unprognostic (3.14e-1)" "unprognostic (5.04e-2)" "unprognostic (1.66e-1)" 0.7 0.3 0.5 0.9 0.8 2.1 2.8 0.5 0.6 0.6 0.3 0.8 0.7 0.6 1.5 0.8 1.1 0.5 0.2 0.6 0.5 0.6 1.3 0.7 1.2 0.9 0.6 0.8 0.8 0.6 0.5 0.7 0.6 1.6 0.8 1.7 3.9 0.5 0.1 2.1 0.7 0.6 0.7 0.8 0.6 10.5 0.7 2.8 0.7 0.2 1.4 0.5 0.6 1.2 5.4 1.0 6.9 0.0 0.5 1.9 0.0 5.7 6.9 5.3 6.5 0.1 4.4 6.3 4.9 2.0 10.5 4.2 2.9 3.8 9.4 5.3 1.1 7.7 0.8 1.6 0.2 2.3 4.3 0.5 2.7 11.0 5.5 1.0 4.0 7.8 5.2 6.3 11.2 1.2 4.9 2.6 1.6 4.6 6.3 5.9 12.6 2.0 0.8 2.1 3.9 3.4 3.3 0.4 1.5 3.3 7.9 2.0 2.9 10.8 2.4 4.8 7.2 1.5 1.8 5.3 1.5 12.6 7.3 4.0 0.5 0.8 1.0 0.7 1.1 0.3 0.9 1.7 0.1 0.7 1.2 1.4 0.4 1.1 0.8 0.5 1.7 0.5 0.5 0.8 0.5 0.6 0.6 0.5 0.9 0.6 0.6 0.7 0.7 1.2 2.4 3.2 1.1 5.2 2.3 5.0 2.1 2.2 2.2 6.4 4.2 2.8 0.6 0.0 2.9 0.0 0.0 0.9 2.9 1.1 0.0 2.3 42.8 2.6 2.0 3.4 1.2 26.3 1.2 3.5 0.4 2.5 3.6 1.4 8.9 4.4 1.4 1.4 3.2 3.3 2.0 2.1 0.0 2.6 3.3 25.8 4.4 2.6 3.6 1.0 0.7 3.6 8.2 5.0 6.1 1.8 0.5 2.2 1.2 1.1 0.2 1.0 5.3 2.8 6.6 2.2 2.3 99.7 34.5 3.2 3.8 0.1 3.4 0.9 1.7 1.2 CCDC154 "C16orf29, LOC645811" ENSG00000197599 "Coiled-coil domain containing 154" 16 1434383-1444556 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 11.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 51.6" "Cancer enhanced" "Detected in many" "prostate cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.5;NB-4: 4.7;SCLC-21H: 33.2;U-266/70: 5.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.9" "HPA041158, HPA043535, HPA048237" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 43: Testis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "Golgi apparatus" "HPA041158: , HPA043535: AB_2678536, HPA048237: AB_2680323" "unprognostic (2.40e-1)" "unprognostic (1.42e-2)" "unprognostic (5.97e-4)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (5.76e-3)" "unprognostic (7.96e-2)" "unprognostic (3.01e-3)" "unprognostic (1.67e-1)" "unprognostic (5.34e-2)" "unprognostic (4.19e-5)" "unprognostic (2.35e-2)" "unprognostic (8.02e-6)" "unprognostic (9.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (9.35e-5)" 0.6 0.8 1.5 0.9 1.7 1.0 0.8 1.7 2.2 1.9 0.5 1.2 1.4 1.0 0.3 0.4 1.9 0.5 0.7 1.4 1.3 2.3 0.7 0.8 1.4 1.8 1.4 1.5 1.2 0.1 3.8 0.4 1.6 1.5 0.1 0.8 0.7 0.4 0.8 1.5 1.2 0.2 0.9 2.2 2.0 11.6 1.5 0.4 2.8 0.1 0.4 0.8 0.9 2.4 9.5 0.4 0.3 0.6 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.4 0.3 0.1 0.5 0.1 0.3 0.1 0.0 0.1 0.0 0.1 1.2 0.5 0.0 0.7 0.0 4.7 0.2 0.0 0.1 2.8 0.1 0.2 0.0 0.2 33.2 0.5 0.1 0.2 1.4 0.1 1.0 2.4 0.0 0.4 0.1 0.4 0.0 5.8 1.6 0.1 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.7 2.2 1.4 1.3 1.8 1.4 1.6 0.9 1.5 2.4 0.2 0.0 0.0 9.8 1.4 0.0 0.5 0.2 0.0 3.2 0.5 0.6 0.6 1.5 0.1 3.7 8.4 0.0 0.4 0.1 0.0 0.1 51.6 0.3 0.3 0.1 0.0 0.0 3.9 0.4 0.0 0.3 1.1 0.3 1.3 1.5 0.4 0.2 0.8 6.7 4.8 0.5 0.0 0.3 0.8 11.1 1.5 0.6 1.8 7.5 0.8 2.4 0.0 2.0 3.8 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.8 4.2 0.0 0.3 0.6 10.1 1.2 0.0 0.4 0.0 0.7 0.4 0.0 0.2 CCDC170 "bA282P11.1, C6orf97, FLJ23305" ENSG00000120262 "Coiled-coil domain containing 170" Q8IYT3 6 151494017-151621193 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "fallopian tube: 33.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 236.6;Late spermatids: 82.6;Respiratory ciliated cells: 379.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 6.2" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "MCF7: 10.4;T-47d: 5.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA027114, HPA027185" Enhanced Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Golgi apparatus" "Cell Junctions" "HPA027114: AB_2732435, HPA027185: AB_2672151" "unprognostic (7.46e-2)" "unprognostic (3.54e-2)" "unprognostic (6.93e-2)" "prognostic favorable (3.64e-4)" "unprognostic (2.13e-1)" "unprognostic (8.79e-3)" "unprognostic (2.74e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (1.96e-1)" "unprognostic (2.36e-1)" "unprognostic (2.18e-2)" "unprognostic (3.56e-2)" "unprognostic (1.40e-2)" "unprognostic (3.93e-2)" "unprognostic (2.17e-1)" "unprognostic (5.21e-2)" 3.0 4.2 1.5 1.3 1.4 0.1 3.7 0.9 0.7 3.0 8.0 0.7 2.5 3.6 0.4 0.4 33.4 1.3 0.8 1.3 1.8 0.8 1.3 4.1 1.4 3.6 4.9 5.6 0.1 0.1 0.2 1.4 3.1 0.4 0.6 0.2 0.2 0.4 0.3 0.2 1.1 0.9 3.2 2.2 1.7 2.7 1.7 0.3 5.6 0.1 0.6 1.1 0.5 2.8 0.0 0.1 0.3 0.0 0.3 0.3 0.0 0.1 0.4 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.1 0.1 10.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 5.9 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.1 6.2 0.0 2.8 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.8 0.1 2.8 0.1 0.0 0.6 1.5 1.4 0.9 0.7 1.3 1.8 3.6 4.9 3.1 3.2 1.7 2.8 1.2 3.2 1.5 7.5 0.4 0.6 0.3 6.5 1.2 0.3 27.3 8.9 0.7 0.0 39.5 0.0 22.9 0.1 0.4 1.1 0.0 0.3 53.0 236.6 23.6 1.2 0.0 0.0 5.5 1.1 0.4 5.2 3.1 14.1 3.8 3.5 1.1 1.5 11.9 0.0 5.9 0.0 12.2 17.5 11.3 82.6 7.2 16.8 0.0 0.0 11.0 2.5 0.0 3.0 0.8 2.7 5.8 0.0 0.1 0.9 0.5 5.8 379.4 1.0 0.0 0.4 6.5 19.1 1.1 0.2 1.0 0.0 1.2 14.0 0.3 0.5 CCDC24 MGC45441 ENSG00000159214 "Coiled-coil domain containing 24" Q8N4L8 1 43991359-43996528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 36.4;Respiratory ciliated cells: 57.6;Spermatocytes: 50.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "eosinophil: 1.0;intermediate monocyte: 2.2;memory B-cell: 3.5;naive B-cell: 2.2;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 5 "B-cells: 3.5;granulocytes: 1.0;monocytes: 2.2" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA035424, HPA061710" Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Nucleoli, Cytosol" "HPA035424: AB_2674619, HPA061710: AB_2684591" "prognostic favorable (3.06e-5)" "unprognostic (1.47e-1)" "unprognostic (1.13e-2)" "unprognostic (1.05e-1)" "unprognostic (1.65e-2)" "prognostic favorable (3.18e-4)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.92e-2)" "unprognostic (6.38e-2)" "unprognostic (2.81e-1)" "unprognostic (7.00e-3)" "unprognostic (3.00e-1)" "unprognostic (1.74e-2)" "unprognostic (6.91e-2)" "unprognostic (1.51e-1)" "unprognostic (7.84e-2)" "unprognostic (2.15e-3)" 1.6 4.8 11.8 1.3 11.9 0.4 3.3 11.3 15.9 5.9 12.3 3.8 1.9 3.2 1.9 2.1 11.2 3.1 1.3 11.8 12.0 11.8 3.6 2.9 1.4 11.6 11.8 2.4 5.6 6.2 12.9 1.0 11.7 7.2 2.1 6.6 4.4 5.0 0.8 1.1 2.4 1.3 11.8 2.4 3.8 19.1 12.3 0.9 9.1 0.2 1.0 4.1 2.4 11.5 4.7 2.8 1.2 1.4 1.2 0.8 2.7 0.2 1.9 1.4 2.4 1.8 13.4 3.8 5.0 0.5 4.0 4.7 0.7 6.5 1.3 3.9 1.6 1.9 1.7 0.5 1.3 0.6 3.2 0.3 0.6 4.5 0.4 4.3 1.1 1.4 0.8 1.4 2.0 4.0 0.2 1.4 2.7 4.2 2.2 1.3 0.0 0.7 5.5 1.8 2.9 2.6 4.0 2.3 2.6 2.5 6.7 0.1 0.3 2.1 5.9 1.5 0.7 0.5 1.8 0.8 5.3 0.5 1.7 0.0 0.4 1.0 0.3 2.2 0.2 3.5 0.1 0.1 0.4 2.2 0.0 0.0 0.4 0.3 1.8 0.3 0.0 0.2 11.8 11.9 11.3 15.9 11.8 12.0 11.6 11.8 11.7 11.8 12.3 11.5 1.7 3.2 7.2 17.0 2.3 1.1 7.9 26.5 9.1 8.9 13.3 12.1 1.0 12.8 22.0 9.2 6.2 5.6 0.9 11.3 21.5 9.4 20.7 30.9 2.4 2.1 36.4 1.3 17.7 7.2 2.2 2.5 21.9 6.9 2.5 1.6 2.5 2.6 3.3 3.3 10.0 13.6 14.2 2.0 2.2 11.7 2.1 3.6 3.6 1.9 2.7 10.2 0.0 5.0 2.4 6.5 8.3 3.0 1.8 5.7 6.3 11.5 57.6 15.4 0.0 2.9 3.8 50.6 19.9 3.9 0.9 2.5 1.3 3.9 10.2 11.4 CCDC28A "C6orf80, CCRL1AP, DKFZp586D0623" ENSG00000024862 "Coiled-coil domain containing 28A" 6 138773769-138793319 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055125 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Nucleoplasm "HPA055125: AB_2682705" "unprognostic (1.51e-1)" "unprognostic (6.88e-3)" "unprognostic (2.70e-1)" "unprognostic (6.67e-2)" "unprognostic (7.96e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (2.58e-3)" "unprognostic (3.80e-1)" "unprognostic (8.34e-3)" "unprognostic (4.29e-3)" "unprognostic (1.02e-1)" "prognostic favorable (1.11e-5)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (2.28e-2)" "unprognostic (2.37e-2)" 21.8 48.4 41.8 19.6 42.5 40.1 28.1 38.4 48.7 23.8 47.1 23.8 30.4 16.7 38.1 16.4 35.8 23.8 19.1 43.8 43.2 59.9 67.8 26.2 35.4 38.5 38.8 21.8 35.5 53.0 29.5 32.1 39.3 25.0 24.3 25.6 52.3 20.2 15.7 18.0 30.7 15.9 37.8 29.8 29.3 23.8 41.1 46.5 54.2 21.3 33.6 26.2 17.2 39.0 7.2 12.9 9.5 17.4 17.5 24.4 19.4 11.7 20.3 15.2 24.6 11.1 14.1 31.1 22.3 11.8 21.3 12.3 15.6 16.2 24.4 35.9 35.7 25.3 16.3 22.1 27.6 43.8 25.6 15.7 20.2 10.9 32.0 31.0 25.1 43.1 25.8 42.2 17.1 15.9 36.3 58.0 8.9 28.9 13.2 21.7 9.5 29.2 18.3 10.6 11.8 18.4 15.6 13.8 34.9 18.6 6.7 47.6 19.5 11.9 13.5 22.3 18.0 55.8 53.0 23.1 12.7 27.1 10.6 137.8 91.6 120.6 84.5 96.5 76.4 107.1 88.4 92.8 102.1 106.6 101.5 93.3 249.6 115.8 85.0 90.0 159.8 93.6 41.8 42.5 38.4 48.7 43.8 43.2 38.5 38.8 39.3 37.8 41.1 39.0 24.5 32.1 35.4 12.7 36.5 13.4 25.0 36.9 29.0 16.0 24.6 25.1 11.0 24.3 31.6 36.8 18.8 82.7 42.7 31.7 123.3 19.3 146.8 83.5 11.4 20.7 24.7 39.2 25.6 31.6 49.2 23.2 16.3 15.6 43.1 25.3 29.3 50.8 38.0 10.1 22.3 30.6 38.7 41.5 31.5 99.9 16.8 36.1 32.0 3.7 39.5 24.6 42.2 5.5 17.9 16.8 35.9 15.1 29.7 31.2 81.0 130.9 89.0 14.2 13.1 14.0 15.8 48.6 27.2 15.5 14.9 108.9 35.4 18.1 23.1 36.2 CCDC59 "BR22, HSPC128, TAP26" ENSG00000133773 "Coiled-coil domain containing 59" Q9P031 12 82223681-82358805 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038555 Approved Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA038555: AB_10669543" "unprognostic (1.61e-1)" "unprognostic (6.28e-3)" "unprognostic (1.27e-1)" "unprognostic (2.11e-2)" "unprognostic (1.13e-1)" "unprognostic (6.73e-2)" "unprognostic (1.42e-3)" "unprognostic (1.50e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-2)" "unprognostic (2.62e-1)" "unprognostic (5.56e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (5.73e-2)" "unprognostic (2.01e-1)" "unprognostic (8.86e-2)" "unprognostic (1.02e-2)" 12.9 6.3 7.1 5.2 7.4 40.3 10.9 7.8 10.3 9.2 3.7 10.0 4.2 9.2 10.9 10.6 10.0 7.0 9.0 7.1 6.5 6.5 9.7 8.0 8.8 7.4 6.1 11.3 7.8 9.6 6.7 9.6 7.0 7.0 7.5 4.7 6.7 6.7 16.0 8.5 6.0 8.0 6.1 6.3 7.4 12.3 6.9 12.5 8.6 19.3 11.1 11.1 8.7 10.2 27.2 22.9 18.9 16.0 22.5 20.1 33.1 24.0 28.5 43.4 35.3 52.9 16.0 31.0 12.0 26.0 29.9 18.3 95.3 46.7 36.4 35.7 51.3 34.3 15.1 34.6 66.7 40.3 15.7 36.1 39.0 43.5 55.9 34.6 35.9 55.8 62.8 17.1 26.9 50.6 39.6 57.1 30.4 25.6 54.4 28.4 31.9 27.6 23.4 28.4 33.8 16.4 27.4 15.6 34.6 23.1 32.3 55.0 17.6 18.0 16.3 15.1 45.7 22.7 30.2 66.2 15.7 32.8 29.0 25.9 9.2 18.3 10.7 12.6 22.0 16.4 19.0 20.9 9.9 24.1 22.2 18.7 22.3 14.9 19.0 21.4 29.5 5.9 7.1 7.4 7.8 10.3 7.1 6.5 7.4 6.1 7.0 6.1 6.9 10.2 76.6 67.3 56.3 10.1 81.7 85.8 129.9 84.9 65.4 33.7 57.3 80.1 44.3 40.0 66.5 44.1 22.9 80.0 88.2 33.1 129.1 48.7 125.8 63.1 71.5 62.0 35.8 41.2 9.4 57.5 88.3 61.5 29.6 85.0 78.6 45.8 64.2 53.9 56.8 43.7 9.9 62.5 50.8 70.9 53.8 28.4 53.4 62.0 48.0 5.6 66.9 47.2 64.9 12.1 17.2 54.8 44.0 53.8 54.7 88.1 56.1 93.0 51.5 40.6 19.7 118.1 57.8 204.9 135.2 57.6 89.9 146.8 95.6 43.5 56.7 100.6 CCDC62 "CT109, ERAP75, FLJ40344, TSP-NY" ENSG00000130783 "Coiled-coil domain containing 62" Q6P9F0 12 122774526-122827528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 70.0" "Group enriched" "Detected in some" 13 "Early spermatids: 259.2;Late spermatids: 75.0;Spermatocytes: 188.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2 OS: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039021, HPA058741" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane" "HPA039021: AB_10673604, HPA058741: AB_2683805" "unprognostic (3.39e-2)" "unprognostic (4.16e-2)" "unprognostic (1.46e-2)" "unprognostic (7.48e-2)" "unprognostic (1.58e-2)" "unprognostic (9.37e-2)" "unprognostic (1.65e-1)" "unprognostic (7.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (2.21e-4)" "unprognostic (5.23e-1)" "unprognostic (6.39e-6)" "unprognostic (2.78e-2)" "unprognostic (6.18e-2)" "unprognostic (7.27e-2)" "unprognostic (3.25e-4)" 0.2 0.3 1.2 0.2 1.3 0.2 0.1 0.7 1.8 0.3 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 1.3 0.5 0.1 0.1 0.1 0.3 0.6 0.4 0.1 0.1 0.3 0.7 0.0 0.7 0.1 0.1 1.4 0.1 0.1 0.7 0.4 0.2 0.1 0.2 0.5 0.1 70.0 0.5 0.2 0.1 0.3 0.3 0.1 0.1 2.0 0.1 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.1 0.3 0.1 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.9 0.1 0.0 0.0 0.6 0.8 0.1 0.3 0.4 0.1 0.1 0.0 0.7 0.3 0.2 0.4 0.1 0.0 1.2 0.1 0.0 0.5 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.4 0.2 0.0 0.6 0.1 0.2 2.9 0.1 0.1 0.3 0.3 0.2 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.3 0.0 1.2 1.3 0.7 1.8 1.3 0.5 0.6 0.4 0.7 0.2 0.5 2.0 0.5 0.0 0.0 9.1 2.1 0.5 0.2 0.1 0.6 1.4 0.4 0.5 1.0 0.0 0.0 0.0 4.2 0.1 0.6 0.1 0.0 0.3 259.2 0.5 0.4 0.4 0.0 0.0 11.7 0.2 0.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.1 1.7 8.1 0.2 0.0 0.3 1.7 75.0 3.1 1.3 1.8 3.7 0.2 0.5 1.0 5.0 8.0 0.1 0.0 2.6 0.3 0.5 0.1 0.0 0.0 1.3 13.1 0.5 0.2 188.2 2.9 0.4 0.9 0.0 0.3 0.2 0.3 0.2 CCDC66 DKFZp686C0433 ENSG00000180376 "Coiled-coil domain containing 66" A2RUB6 3 56557161-56621837 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 202.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044185, HPA051937" Approved Supported "Cell Junctions,Midbody ring,Centriolar satellite,Cytosol" Yes No "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Centriolar satellite" "Cell Junctions, Midbody ring, Cytosol" "HPA044185: AB_10965852, HPA051937: " "unprognostic (2.28e-2)" "unprognostic (7.74e-2)" "unprognostic (7.37e-2)" "unprognostic (2.90e-1)" "unprognostic (5.28e-2)" "unprognostic (1.72e-2)" "unprognostic (7.26e-3)" "unprognostic (1.68e-3)" "unprognostic (2.05e-2)" "unprognostic (1.27e-1)" "unprognostic (3.05e-3)" "unprognostic (5.48e-3)" "unprognostic (6.85e-3)" "unprognostic (1.81e-1)" "unprognostic (6.57e-2)" "unprognostic (3.24e-1)" "unprognostic (6.81e-3)" 2.7 3.1 3.8 3.6 3.7 3.0 5.2 3.7 4.3 4.8 4.2 4.0 3.0 4.1 5.3 2.5 5.7 3.4 2.9 3.7 4.2 4.1 2.0 3.6 4.9 3.8 3.7 6.0 3.3 5.4 4.5 3.3 3.9 4.0 4.1 7.8 3.3 3.6 4.5 2.5 2.8 4.9 3.8 4.3 3.2 3.7 3.7 5.1 4.9 2.6 4.9 3.7 3.1 3.8 5.6 2.0 5.8 3.7 8.9 5.2 4.6 6.8 6.4 9.1 7.8 4.3 4.3 15.6 1.6 3.8 5.8 2.8 3.4 6.5 10.1 5.6 4.0 9.5 9.0 4.6 6.2 12.8 3.3 4.9 8.8 7.7 5.1 8.0 6.0 7.7 9.3 2.4 7.2 4.7 10.0 7.5 9.7 4.8 7.5 3.4 5.2 8.6 5.3 1.9 2.2 4.2 8.7 5.5 5.2 4.9 1.9 5.2 3.1 6.6 5.2 6.3 9.9 4.7 5.3 8.0 4.9 14.3 5.5 10.0 1.5 3.5 4.1 2.0 5.4 2.7 7.0 5.0 1.1 1.6 8.0 5.8 0.3 5.1 2.4 1.0 14.8 2.6 3.8 3.7 3.7 4.3 3.7 4.2 3.8 3.7 3.9 3.8 3.7 3.8 39.7 22.4 22.6 42.7 41.3 28.2 20.1 30.5 15.9 68.5 18.5 21.0 30.5 30.0 29.0 22.0 108.4 23.0 51.5 7.7 29.4 23.7 202.5 58.1 33.5 28.8 21.0 40.8 93.2 10.5 14.6 29.9 18.8 13.9 34.2 38.3 37.9 8.5 18.4 52.2 95.8 11.4 22.4 35.8 27.9 109.6 54.0 20.7 26.6 51.5 56.1 36.8 105.0 70.9 96.7 14.1 9.8 47.8 28.1 25.5 11.5 20.3 51.5 111.5 32.9 38.6 30.9 55.8 46.8 12.1 29.5 16.4 51.7 33.6 14.5 11.4 CCDC69 "DKFZP434C171, FLJ13705" ENSG00000198624 "Coiled-coil domain containing 69" A6NI79 5 151181052-151224093 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 351.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 124.5;dendritic cells: 106.9;Granulosa cells: 138.2;NK-cells: 197.8;Plasma cells: 133.6;Theca cells: 132.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 129.2;Daudi: 199.9;U-266/70: 120.5;U-698: 119.1" "Region enhanced" "Detected in some" "cerebellum: 4.8" "Low region specificity" "Detected in all" "HPA043648, HPA052896" Uncertain Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments" "HPA043648: AB_10795877, HPA052896: AB_2681983" "prognostic favorable (3.21e-4)" "unprognostic (2.60e-2)" "unprognostic (1.28e-1)" "unprognostic (2.78e-2)" "unprognostic (5.62e-2)" "unprognostic (8.63e-3)" "unprognostic (3.07e-2)" "unprognostic (6.48e-2)" "unprognostic (2.00e-1)" "unprognostic (9.29e-2)" "unprognostic (3.85e-2)" "unprognostic (1.55e-2)" "unprognostic (3.67e-1)" "unprognostic (4.31e-2)" "unprognostic (3.69e-1)" "unprognostic (2.93e-1)" "unprognostic (2.01e-1)" 108.9 89.6 6.7 45.8 8.4 46.3 60.5 12.2 7.9 15.2 13.4 138.5 19.6 32.9 13.3 54.1 37.1 19.3 96.9 5.9 8.9 10.7 24.0 39.0 70.4 13.3 13.8 27.1 47.5 32.1 8.5 14.8 13.6 23.0 20.5 1.8 14.4 29.4 351.9 13.3 44.7 45.6 11.3 55.4 37.0 13.2 9.2 37.8 11.6 163.8 66.8 87.7 21.9 7.2 8.0 1.6 0.4 6.4 129.2 13.1 4.2 1.5 13.1 2.6 2.4 2.1 1.1 199.9 6.3 0.5 3.3 1.0 3.0 2.8 0.9 0.1 2.7 27.0 0.0 17.5 21.1 9.9 34.4 33.0 0.2 1.0 0.0 2.5 13.1 0.0 23.7 44.0 0.1 0.6 43.8 23.3 7.5 0.1 15.2 36.0 1.0 12.1 0.5 5.9 0.2 0.8 2.4 3.2 1.7 3.2 2.0 24.0 32.0 1.0 6.1 0.6 1.5 120.5 60.1 119.1 1.4 22.2 0.0 30.9 12.4 13.5 11.3 10.9 10.3 5.4 8.8 10.8 10.0 10.4 6.1 6.6 9.6 14.3 10.3 19.3 8.5 11.5 6.7 8.4 12.2 7.9 5.9 8.9 13.3 13.8 13.6 11.3 9.2 7.2 51.0 12.8 78.4 0.7 68.8 2.5 3.0 3.5 1.2 0.4 4.8 2.4 124.5 1.5 13.5 1.8 0.0 7.3 106.9 0.2 0.0 2.9 0.5 26.8 2.7 58.9 1.8 32.2 1.8 20.0 9.6 18.4 7.1 1.3 34.8 138.2 28.2 39.7 7.3 6.7 2.7 0.0 4.1 64.0 12.2 2.4 5.6 46.5 10.6 11.2 73.5 4.9 197.8 1.0 0.6 8.8 0.1 7.9 133.6 3.6 4.5 3.2 51.3 1.4 13.1 4.7 14.8 1.2 1.0 0.7 1.3 35.4 65.7 132.1 0.9 23.5 CCDC8 "3M3, DKFZp564K0322, PPP1R20" ENSG00000169515 "Coiled-coil domain containing 8" Q9H0W5 19 46410329-46413564 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Dwarfism "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 36.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 27.0;Distal tubular cells: 39.2;Granulosa cells: 25.7;Leydig cells: 70.8;Peritubular cells: 57.9;Theca cells: 32.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 18.5;AN3-CA: 22.2;HSkMC: 19.6;K-562: 20.3;RH-30: 24.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041993 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041993: AB_10795388" "unprognostic (3.05e-3)" "unprognostic (2.16e-1)" "unprognostic (2.28e-2)" "unprognostic (1.13e-1)" "unprognostic (1.39e-3)" "unprognostic (3.69e-1)" "unprognostic (6.64e-2)" "unprognostic (5.16e-2)" "unprognostic (7.77e-2)" "unprognostic (1.62e-1)" "unprognostic (1.15e-1)" "unprognostic (5.72e-2)" "prognostic favorable (1.72e-5)" "unprognostic (5.43e-3)" "unprognostic (5.77e-2)" "unprognostic (4.09e-2)" "unprognostic (4.18e-3)" 4.1 16.3 4.1 2.7 3.8 0.7 8.8 3.9 2.6 13.9 7.5 3.3 0.9 13.9 10.5 1.3 22.9 4.2 24.7 3.6 3.9 11.2 0.7 4.4 0.9 5.2 7.4 36.8 13.6 9.1 12.9 6.7 5.3 6.4 1.2 1.3 10.8 7.5 2.1 3.1 2.2 6.5 4.8 2.3 2.2 5.9 4.2 5.6 9.0 2.4 0.8 7.5 7.3 4.4 1.9 0.1 18.5 22.2 4.8 6.0 8.9 9.6 0.0 2.1 0.9 0.1 0.1 0.2 12.5 7.6 0.4 0.2 0.1 15.0 1.0 0.0 9.4 0.0 0.2 1.0 16.0 0.1 0.1 19.6 0.0 5.2 15.2 0.3 0.1 0.1 20.3 0.0 6.8 0.0 0.0 1.3 13.3 0.0 0.0 0.7 24.8 0.0 16.1 0.1 2.9 0.1 0.1 0.1 0.1 14.2 0.1 4.7 1.7 1.2 4.9 0.2 0.4 0.1 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 4.1 3.8 3.9 2.6 3.6 3.9 5.2 7.4 5.3 4.8 4.2 4.4 0.7 0.0 1.1 1.3 0.0 0.9 6.5 1.5 0.0 0.4 1.8 19.3 27.0 7.2 4.0 11.0 0.0 7.5 0.1 0.0 39.2 14.8 0.4 15.0 13.9 1.2 0.0 0.0 0.0 1.1 10.0 17.3 0.0 3.9 1.3 25.7 1.1 0.0 1.7 0.0 0.0 0.0 2.0 0.0 0.9 2.9 70.8 0.6 1.8 1.0 0.0 14.6 0.0 1.5 0.1 3.6 0.0 57.9 0.0 3.7 0.0 1.2 2.4 0.5 13.1 12.3 8.3 0.4 5.5 0.0 0.1 2.1 0.2 32.7 0.0 0.8 CCDC83 "CT148, FLJ42119, KP-CoT-23, MGC34732" ENSG00000150676 "Coiled-coil domain containing 83" Q8IWF9 11 85855101-85920021 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 115 "testis: 35.5" "Group enriched" "Detected in some" 46 "Early spermatids: 222.2;Late spermatids: 194.2;Spermatocytes: 160.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 6 "MCF7: 2.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA039707, HPA039882" Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039707: AB_10795259, HPA039882: AB_10795410" "unprognostic (1.14e-1)" "unprognostic (4.09e-1)" "unprognostic (1.49e-2)" "unprognostic (4.43e-2)" "unprognostic (7.05e-6)" "unprognostic (3.52e-1)" "unprognostic (2.17e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 35.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 222.2 0.1 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 194.2 4.1 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.1 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 160.3 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCDC85C ENSG00000205476 "Coiled-coil domain containing 85C" A6NKD9 14 99500190-99604207 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 62.6;Rod photoreceptor cells: 51.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058346, HPA061922" Uncertain Approved "Nucleoplasm,Nucleoli rim,Nuclear bodies,Mitotic chromosome,Cell Junctions" Yes No "Cluster 20: T-cells - T-cell receptor" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" "Nucleoli rim, Cell Junctions" "Nucleoplasm, Nuclear bodies, Mitotic chromosome" "HPA058346: AB_2683686, HPA061922: " "unprognostic (7.17e-2)" "unprognostic (2.23e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (5.70e-2)" "unprognostic (2.61e-1)" "unprognostic (1.68e-3)" "unprognostic (4.80e-2)" "unprognostic (1.45e-2)" "unprognostic (8.75e-2)" "unprognostic (3.30e-1)" "unprognostic (1.68e-3)" "prognostic favorable (2.60e-5)" "unprognostic (4.14e-2)" "unprognostic (1.95e-1)" "unprognostic (8.74e-3)" "unprognostic (9.81e-3)" 5.2 22.0 26.4 4.3 32.9 9.7 7.1 72.9 27.1 5.8 20.6 31.3 18.7 15.4 14.3 28.3 11.3 5.4 19.6 24.8 20.9 14.4 18.2 8.1 2.5 30.8 24.1 5.1 18.5 16.4 17.0 8.6 27.0 15.0 11.1 34.7 26.4 16.2 20.7 19.4 17.7 13.1 24.5 3.6 19.2 8.5 28.6 5.0 9.3 5.6 7.5 16.1 8.9 21.0 48.4 43.4 52.7 31.7 0.7 0.2 48.9 16.0 16.2 31.4 18.1 52.9 49.8 0.3 61.7 18.2 8.6 63.3 39.2 38.4 19.5 79.2 23.3 2.5 43.6 36.1 4.2 0.5 4.9 0.1 19.9 9.0 25.9 18.6 9.9 27.9 11.8 7.2 3.9 80.3 21.8 6.6 19.3 55.4 44.7 32.1 22.1 10.8 22.3 18.8 26.0 32.6 40.7 21.5 9.5 19.9 46.9 9.8 22.6 6.2 51.5 22.4 16.2 11.2 15.8 0.4 1.0 4.3 4.5 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.4 0.1 26.4 32.9 72.9 27.1 24.8 20.9 30.8 24.1 27.0 24.5 28.6 21.0 8.5 22.4 5.6 15.7 6.7 8.8 8.7 4.0 13.6 35.2 12.1 9.3 3.0 5.7 7.3 1.8 62.6 6.3 3.9 21.2 0.0 7.6 3.1 18.8 8.1 9.2 9.6 3.4 2.8 9.4 4.5 6.2 17.3 35.6 6.3 14.1 5.3 16.7 1.8 1.7 5.4 9.6 6.1 1.6 1.2 2.1 0.6 5.0 8.8 4.7 0.4 30.6 1.0 1.5 11.7 17.4 13.2 0.7 10.4 11.0 23.3 6.5 3.0 51.7 0.0 5.7 4.1 1.4 3.5 20.4 14.1 4.9 8.3 2.3 13.0 12.0 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 CCDC97 "FLJ40267, MGC20255" ENSG00000142039 "Coiled-coil domain containing 97" Q96F63 19 41310172-41324873 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043320, HPA043572" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Plasma membrane, Cytosol" "HPA043320: AB_10964344, HPA043572: AB_10962488" "unprognostic (9.25e-3)" "unprognostic (7.26e-2)" "unprognostic (1.68e-1)" "unprognostic (5.10e-2)" "unprognostic (1.04e-1)" "unprognostic (1.51e-2)" "prognostic unfavorable (1.09e-4)" "unprognostic (8.40e-2)" "unprognostic (1.91e-2)" "unprognostic (2.44e-1)" "unprognostic (5.93e-3)" "unprognostic (4.51e-2)" "unprognostic (2.16e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-1)" "unprognostic (7.92e-2)" "unprognostic (1.65e-2)" 14.6 12.9 19.0 17.8 21.3 23.0 14.3 17.7 17.7 20.3 14.4 14.0 14.2 17.3 23.4 20.2 21.9 12.3 15.6 16.5 18.2 12.0 11.8 14.3 23.8 23.5 20.2 24.0 17.7 15.8 13.7 10.5 19.9 16.2 11.2 10.7 18.0 14.6 30.6 20.2 16.6 14.2 18.1 20.0 15.7 32.1 20.4 21.9 16.3 20.5 22.2 14.8 17.2 20.5 25.2 54.1 28.2 32.9 36.2 28.7 20.3 16.6 13.4 25.7 21.9 32.4 23.6 23.9 17.4 13.9 17.3 16.7 38.8 33.1 19.5 44.1 37.6 21.9 25.5 21.5 27.5 36.6 45.3 28.1 41.7 30.0 25.0 21.1 18.0 25.8 28.5 44.4 24.9 18.3 33.6 8.9 13.2 30.5 19.3 37.5 22.4 17.5 23.7 47.3 25.1 22.2 37.0 40.3 16.5 18.6 27.5 27.6 21.6 22.1 22.0 11.5 27.8 45.3 42.2 22.7 21.0 26.7 30.0 9.4 7.2 8.5 12.0 7.6 13.4 9.1 8.1 8.7 5.8 10.0 8.7 7.8 11.9 10.4 12.6 6.3 7.2 8.1 19.0 21.3 17.7 17.7 16.5 18.2 23.5 20.2 19.9 18.1 20.4 20.5 7.3 12.8 6.7 5.2 22.3 4.6 11.4 11.3 6.2 11.8 11.2 8.8 6.7 7.2 8.9 9.2 12.5 11.1 23.9 13.5 7.9 13.1 3.7 9.3 8.6 8.4 11.5 7.8 4.1 26.1 4.5 10.0 15.3 9.8 16.5 11.2 9.7 6.5 15.3 10.1 4.7 12.1 18.3 10.0 7.9 8.4 12.8 12.3 1.8 3.7 16.1 7.1 25.7 1.0 6.6 20.5 5.9 11.3 18.6 10.0 16.7 9.3 12.2 8.5 0.0 13.1 8.5 22.5 12.9 10.8 5.8 18.3 20.1 7.2 10.7 13.3 CCKAR ENSG00000163394 "Cholecystokinin A receptor" P32238 4 26481396-26490484 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.9;gallbladder: 29.2;stomach 1: 16.5" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "stomach cancer: 0.5" "Group enriched" "Detected in some" 5 "hypothalamus: 5.1;midbrain: 6.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "hypothalamus: 7.2" "Region enhanced" "Detected in all" "midbrain: 12.6" HPA073900 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA073900: " "unprognostic (7.48e-2)" "unprognostic (3.70e-2)" "unprognostic (7.13e-2)" "unprognostic (3.08e-2)" "unprognostic (3.36e-1)" "unprognostic (3.79e-1)" 0.0 0.0 0.5 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.0 0.3 1.6 0.0 0.0 0.0 0.0 29.2 0.0 0.6 5.1 0.1 0.0 0.0 0.0 0.8 6.9 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.5 0.1 1.1 0.3 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.4 0.6 5.1 0.8 6.9 0.6 0.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCNT2 ENSG00000082258 "Cyclin T2" O60583 2 134918235-134959342 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Host-virus interaction, Transcription, Transcription regulation" Cyclin "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005559 Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA005559: AB_1078608" "unprognostic (2.49e-2)" "unprognostic (1.19e-1)" "unprognostic (9.57e-2)" "unprognostic (1.25e-1)" "unprognostic (4.92e-2)" "unprognostic (2.65e-3)" "unprognostic (1.85e-2)" "unprognostic (1.00e-2)" "unprognostic (1.61e-2)" "unprognostic (1.21e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (2.44e-4)" "prognostic unfavorable (1.25e-5)" "unprognostic (2.33e-1)" "unprognostic (8.51e-2)" "unprognostic (9.94e-2)" "prognostic favorable (3.28e-4)" 13.4 12.1 10.1 12.2 10.2 29.0 15.6 13.7 12.4 16.4 10.6 13.0 13.4 13.5 14.8 12.8 14.0 9.4 11.7 9.9 10.8 10.9 18.3 14.9 15.5 10.4 10.0 17.4 19.8 15.0 15.1 12.0 10.8 13.5 12.1 19.0 13.0 10.7 10.3 15.4 14.4 8.5 11.1 15.6 14.8 12.3 10.5 14.4 14.5 9.7 14.1 15.0 16.3 14.4 9.0 4.4 28.0 10.5 13.6 13.7 21.3 12.2 9.9 11.2 13.9 11.9 10.1 14.6 8.9 10.0 5.4 11.4 17.0 9.1 16.3 7.9 11.5 15.8 11.9 16.9 13.3 14.3 13.4 12.6 17.6 11.1 13.5 14.4 16.8 10.8 13.4 14.6 13.2 6.1 16.0 21.2 22.8 7.4 9.0 15.2 10.0 11.7 17.4 24.4 19.1 15.8 8.9 10.3 14.2 20.3 10.8 17.3 15.3 14.4 15.9 6.2 9.0 10.2 6.7 15.1 9.0 11.2 12.5 3.8 1.6 2.0 1.7 2.0 2.1 1.6 1.9 2.1 2.1 1.2 3.3 2.6 2.1 2.8 1.0 1.9 2.6 1.3 10.1 10.2 13.7 12.4 9.9 10.8 10.4 10.0 10.8 11.1 10.5 14.4 27.1 25.6 26.0 49.6 38.0 15.0 28.8 17.9 26.7 34.7 21.6 15.4 23.5 14.3 21.8 14.7 33.3 11.9 35.3 22.4 7.9 16.2 5.5 20.2 30.2 21.5 18.5 20.0 73.6 14.9 9.6 23.7 46.9 33.1 11.4 31.1 18.9 20.9 10.1 42.1 70.1 16.4 6.1 15.7 22.1 14.6 14.0 25.2 8.8 52.5 23.6 12.9 19.6 76.9 81.8 14.2 19.0 22.2 26.5 35.4 19.1 7.0 12.4 34.5 19.7 17.7 24.2 17.7 23.6 25.3 18.2 13.7 29.0 25.2 17.1 50.5 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 40.4;Kupffer cells: 43.1;Macrophages: 25.2;monocytes: 34.9;Plasma cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 185.5;THP-1: 89.8;U-266/70: 416.5;U-266/84: 177.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.6 1.9 0.1 25.9 0.1 1.9 3.1 0.1 0.2 1.6 0.3 4.6 7.5 1.2 0.9 1.2 1.2 3.4 1.1 0.1 0.1 1.2 2.1 5.8 11.6 0.4 0.2 1.1 0.8 0.3 0.2 0.8 0.2 1.2 5.1 0.0 3.1 1.7 0.5 1.9 5.7 7.1 0.3 20.4 5.2 1.0 0.2 4.3 1.1 0.5 7.2 5.5 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 2.7 0.0 185.5 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.3 416.5 177.7 0.0 0.1 3.3 0.1 560.9 146.2 2.6 11.9 12.8 89.2 7.9 24.3 20.2 145.2 1.8 0.6 0.7 3.8 14.0 0.4 113.6 11.4 81.6 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.2 0.3 0.2 0.3 0.1 0.0 1.3 0.0 5.8 0.3 0.0 0.0 0.6 0.0 0.1 0.1 0.3 1.5 0.0 0.0 0.0 0.1 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 4.4 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.0 1.8 0.9 0.8 0.0 0.0 0.0 0.0 43.1 10.5 0.7 0.0 25.2 0.0 0.0 34.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 8.2 0.1 0.1 0.0 CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46163604-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;granulocytes: 1.3;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3389.4;eosinophil: 2509.9" "Lineage enriched" "Detected in many" 109 "granulocytes: 3389.4" "Cell line enriched" "Detected in some" 10 "RPMI-8226: 29.6" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "CAB003795: AB_562259, HPA069514: " "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" 0.1 0.0 0.2 1.6 0.3 0.4 0.0 0.1 0.5 0.1 1.7 0.8 1.3 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.2 0.1 0.1 0.6 0.5 0.4 0.0 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.7 0.0 0.0 0.1 1.7 0.8 2.6 0.9 0.0 1.5 1.2 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 2.6 0.1 0.8 0.0 0.9 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.0 29.6 0.0 2.4 0.1 0.0 0.1 0.8 0.0 0.8 0.0 0.7 0.0 0.1 0.2 0.0 0.1 3.0 2.6 0.0 0.0 0.5 0.0 3389.4 1.0 2509.9 0.5 1.5 0.8 1.2 2.6 1.4 1.1 0.7 0.3 0.9 115.8 0.5 1.4 3.5 31.1 7.6 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CCT3 "Cctg, TRIC5" ENSG00000163468 "Chaperonin containing TCP1 subunit 3" P49368 1 156308968-156367873 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006543 Approved Approved "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA006543: AB_1078426" "unprognostic (2.14e-2)" "unprognostic (3.20e-3)" "unprognostic (1.66e-1)" "unprognostic (6.00e-3)" "unprognostic (8.39e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (3.87e-7)" "unprognostic (4.43e-3)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (7.16e-2)" "unprognostic (5.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.10e-1)" 85.3 122.3 121.4 103.0 125.8 79.5 119.4 132.2 176.7 77.1 139.0 95.3 87.2 93.6 77.1 106.9 119.9 67.4 100.8 125.3 135.5 114.5 108.3 60.1 123.9 129.4 126.1 113.5 82.3 120.4 65.3 93.3 129.5 86.6 112.9 135.7 74.9 89.8 134.8 93.8 83.3 137.3 132.4 67.1 80.7 120.3 130.2 129.1 87.6 120.8 148.5 136.7 70.6 143.8 432.3 562.3 324.3 311.9 352.5 261.2 419.7 388.8 315.9 617.9 378.0 611.1 396.3 689.5 442.3 337.9 392.5 395.5 1045.2 519.9 519.1 384.3 660.6 437.6 438.6 579.2 261.9 547.7 357.2 333.7 312.4 556.6 514.7 303.3 531.6 425.3 795.2 250.1 375.5 603.5 688.2 372.1 656.4 859.5 702.1 587.3 314.5 771.1 496.9 349.9 434.9 448.1 347.0 635.0 388.7 531.0 560.2 707.3 366.1 249.0 373.0 263.3 717.1 457.5 808.2 975.7 288.1 349.1 408.1 75.1 107.1 49.0 129.0 137.0 171.2 142.1 144.3 138.8 171.7 156.8 177.0 156.7 14.9 145.8 146.8 120.8 164.3 222.3 121.4 125.8 132.2 176.7 125.3 135.5 129.4 126.1 129.5 132.4 130.2 143.8 82.8 54.5 62.5 18.3 104.8 144.9 241.1 247.4 119.5 124.5 133.2 118.5 121.1 98.7 132.3 90.1 106.3 226.7 100.5 71.7 113.5 208.6 111.9 118.4 137.4 122.4 125.3 134.0 29.7 183.2 217.8 113.9 70.8 86.6 73.0 180.1 74.6 88.4 162.6 74.0 34.6 93.8 193.3 83.0 96.5 226.7 83.6 78.1 112.1 22.5 153.6 158.1 105.0 37.2 41.9 199.1 78.8 88.0 95.8 169.0 115.9 212.3 137.6 244.3 118.3 110.3 145.4 410.0 232.4 123.1 159.8 184.6 112.1 347.9 149.8 157.9 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD164L2 ENSG00000174950 "CD164 molecule like 2" Q6UWJ8 1 27379176-27383333 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.9;fallopian tube: 30.0;salivary gland: 13.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 28.5;Endometrial ciliated cells: 53.6;Respiratory ciliated cells: 146.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.2;CAPAN-2: 4.1;HaCaT: 1.9;HBEC3-KT: 2.2;hTCEpi: 2.8;SK-BR-3: 2.6;T-47d: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062915 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA062915: AB_2684903" "unprognostic (8.97e-3)" "unprognostic (2.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "prognostic favorable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (4.47e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (4.07e-2)" "unprognostic (5.91e-6)" "unprognostic (1.33e-2)" "unprognostic (6.42e-2)" "unprognostic (1.34e-2)" "unprognostic (2.71e-2)" 0.1 0.1 0.3 0.0 0.3 0.0 2.5 0.2 0.4 4.9 1.0 0.2 0.0 0.3 0.5 19.9 30.0 0.1 0.0 0.4 0.3 0.9 0.2 5.1 0.0 2.0 1.5 0.0 0.8 0.8 3.4 0.0 0.6 4.1 0.2 0.0 13.5 0.3 0.0 11.1 0.1 0.0 0.8 0.0 0.7 0.5 0.2 0.9 0.4 0.0 1.8 0.0 9.3 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 1.1 0.1 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 2.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.4 0.3 2.0 1.5 0.6 0.8 0.2 0.4 0.2 0.0 3.7 0.0 0.2 2.9 9.6 12.9 28.5 0.0 5.7 14.4 0.9 0.0 10.1 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.2 53.6 0.5 1.5 0.0 0.0 0.2 0.2 0.1 0.5 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.3 0.5 12.2 0.0 0.4 1.6 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.2 3.4 0.0 0.1 146.1 0.0 0.0 0.1 2.8 0.1 1.0 9.3 2.8 0.0 0.4 0.0 0.5 4.4 CD180 "LY64, Ly78, RP105" ENSG00000134061 "CD180 molecule" Q99467 5 67179613-67196799 "CD markers, Predicted membrane proteins" "Immunity, Inflammatory response, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 23.3" "Cell type enhanced" "Detected in some" "B-cells: 53.6;Hofbauer cells: 78.6;Kupffer cells: 23.5;Macrophages: 17.5;monocytes: 13.8;Plasma cells: 39.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 77.0;naive B-cell: 78.9" "Group enriched" "Detected in many" 25 "B-cells: 78.9;dendritic cells: 23.5;monocytes: 34.5" "Group enriched" "Detected in some" 10 "Daudi: 45.2;Karpas-707: 41.1;U-266/70: 33.1;U-266/84: 49.0;U-698: 12.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003740 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Mitotic spindle" Yes NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nucleoli, Mitotic spindle" "HPA003740: AB_1078450" "unprognostic (9.33e-2)" "unprognostic (4.58e-2)" "unprognostic (2.81e-3)" "unprognostic (5.85e-3)" "unprognostic (2.25e-2)" "unprognostic (4.04e-3)" "unprognostic (1.09e-1)" "unprognostic (4.95e-2)" "unprognostic (5.83e-2)" "unprognostic (3.71e-1)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.09e-1)" "unprognostic (1.16e-1)" "unprognostic (3.70e-2)" "unprognostic (1.21e-1)" "unprognostic (2.18e-2)" 1.6 0.7 0.7 9.7 0.7 2.4 6.7 0.6 1.2 0.5 0.4 2.1 2.0 0.5 0.2 0.4 0.4 1.6 0.4 0.8 0.7 0.3 2.5 1.6 23.2 1.5 1.5 0.2 0.3 0.2 0.1 3.2 2.0 0.5 2.7 0.3 1.1 0.4 0.1 0.2 3.9 1.8 1.0 12.9 2.2 0.4 1.8 2.5 0.3 0.2 23.3 3.0 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 45.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 41.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.1 0.6 0.2 33.1 49.0 12.3 0.0 2.7 0.0 0.3 11.8 0.9 0.0 20.4 0.0 77.0 0.1 0.1 22.1 78.9 0.0 0.0 0.9 1.8 34.5 23.5 0.1 8.5 0.7 0.7 0.6 1.2 0.8 0.7 1.5 1.5 2.0 1.0 1.8 2.1 0.1 0.0 0.5 0.3 53.6 0.4 0.1 0.0 0.0 0.1 1.8 1.1 0.7 1.5 0.0 0.0 0.0 0.4 4.0 0.0 0.0 0.0 2.2 0.1 0.0 0.6 0.0 1.7 0.0 0.2 0.3 0.4 0.0 0.1 2.5 0.0 0.0 0.3 78.6 0.0 0.0 0.0 0.0 23.5 8.0 1.0 0.0 17.5 0.0 1.9 13.8 0.1 0.0 0.0 0.0 0.3 0.0 0.0 39.6 0.0 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.7 2.2 0.0 0.1 0.1 CD2 SRBC ENSG00000116824 "CD2 molecule" P06729 1 116754430-116769229 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 249.8" "Group enriched" "Detected in many" 6 "dendritic cells: 158.3;NK-cells: 178.2;T-cells: 476.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 6 "gdT-cell: 421.8;MAIT T-cell: 403.1;memory CD4 T-cell: 610.2;memory CD8 T-cell: 714.1;naive CD4 T-cell: 316.3;naive CD8 T-cell: 486.2;NK-cell: 1108.0;T-reg: 655.2" "Group enriched" "Detected in all" 10 "NK-cells: 1108.0;T-cells: 714.1" "Group enriched" "Detected in some" 25 "HDLM-2: 224.1;JURKAT: 145.8;MOLT-4: 166.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB002430, HPA003883" Enhanced Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "CAB002430: AB_442057, HPA003883: AB_1846263" "prognostic favorable (4.36e-4)" "prognostic favorable (1.47e-4)" "unprognostic (3.34e-3)" "prognostic favorable (1.69e-5)" "unprognostic (1.52e-1)" "prognostic favorable (7.46e-5)" "unprognostic (9.32e-3)" "unprognostic (1.61e-2)" "prognostic favorable (3.97e-5)" "prognostic favorable (7.72e-4)" "unprognostic (4.18e-2)" "unprognostic (3.31e-1)" "prognostic unfavorable (4.82e-6)" "unprognostic (6.16e-2)" "unprognostic (6.61e-2)" "unprognostic (2.73e-2)" "unprognostic (7.63e-3)" 4.6 4.6 0.6 51.3 0.7 11.4 7.6 0.6 1.0 5.8 0.8 13.9 17.2 3.7 2.8 8.4 4.2 16.8 2.6 0.5 0.8 2.5 7.8 21.0 119.6 1.7 0.7 2.8 2.9 0.9 0.7 1.0 1.1 5.2 16.0 0.0 8.6 2.3 1.4 3.5 28.4 4.4 1.0 44.1 24.1 1.8 1.0 249.8 3.8 1.7 79.1 20.8 3.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 224.1 0.0 0.4 0.0 0.0 0.0 0.4 7.2 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.1 0.5 0.0 0.0 166.9 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.4 0.0 11.3 5.2 1.6 421.8 3.7 403.1 3.8 610.2 714.1 95.4 2.5 316.3 486.2 14.1 1108.0 2.8 21.0 655.2 565.1 0.6 0.7 0.6 1.0 0.5 0.8 1.7 0.7 1.1 1.0 1.0 1.1 5.0 3.2 17.5 0.0 12.3 5.0 0.4 0.0 2.2 0.0 4.0 4.7 2.1 0.0 2.5 3.7 0.0 0.1 158.3 0.2 0.0 0.5 23.5 1.1 1.0 2.9 3.0 24.0 0.0 0.0 0.0 2.5 10.7 0.9 5.1 0.0 8.2 1.5 0.6 0.0 0.0 0.0 0.0 10.9 16.6 7.8 0.6 19.1 1.8 1.0 15.5 0.0 178.2 0.0 0.0 0.0 0.0 0.4 42.3 0.1 0.0 1.7 0.0 0.0 0.0 2.9 4.1 0.3 0.2 0.4 3.7 0.0 476.8 0.0 0.5 0.2 CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;granulocytes: 15.2;Hepatic stellate cells: 14.6;Hofbauer cells: 31.8;Langerhans cells: 19.9;T-cells: 12.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 234.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 234.9" "Cell line enriched" "Detected in some" 8 "HEL: 25.5" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" NA NA 2000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" 1.7 1.2 0.3 3.0 0.4 1.7 1.4 0.2 0.6 0.7 0.7 1.5 1.6 0.7 0.3 3.8 0.5 1.9 0.6 0.4 0.3 0.5 2.4 1.9 4.4 0.3 0.2 0.3 0.5 0.5 0.2 5.3 0.3 0.6 2.3 0.1 0.6 0.7 0.1 2.6 2.0 1.1 0.2 7.9 1.5 0.7 0.2 3.4 0.5 0.9 4.6 1.9 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 25.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.2 0.0 234.9 2.9 53.6 4.0 1.3 7.0 9.9 13.8 7.9 22.9 5.6 13.4 6.1 0.8 2.5 0.4 0.5 4.3 5.2 0.3 0.4 0.2 0.6 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.0 1.1 1.6 4.4 1.9 0.1 0.0 14.8 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.1 1.0 0.1 0.5 0.0 4.0 5.7 0.0 0.2 0.9 0.0 0.1 15.2 0.0 14.6 0.1 31.8 0.0 2.2 0.0 0.0 6.7 19.9 0.0 0.0 9.1 5.4 5.6 5.2 0.0 0.0 1.0 0.7 0.1 0.0 0.0 2.7 0.1 0.0 0.1 1.2 0.0 0.0 0.3 0.4 0.8 0.3 5.8 0.9 0.7 12.4 0.0 0.0 0.2 CD226 "DNAM-1, DNAM1, PTA1, TLiSA1" ENSG00000150637 "CD226 molecule" Q15762 18 69831158-69961803 "CD markers, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 20.2;parathyroid gland: 62.4" "Cell type enhanced" "Detected in many" "dendritic cells: 52.1;Macrophages: 24.4;Microglial cells: 22.5;NK-cells: 90.6;Oligodendrocytes: 26.6;T-cells: 43.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 36.6;MAIT T-cell: 13.4;memory CD4 T-cell: 28.8;memory CD8 T-cell: 22.5;naive CD4 T-cell: 15.8;naive CD8 T-cell: 17.3;NK-cell: 29.7;T-reg: 11.3" "Group enriched" "Detected in many" 11 "NK-cells: 29.7;T-cells: 36.6" "Group enriched" "Detected in some" 6 "HEL: 100.0;HMC-1: 42.6" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA015715, HPA015865" Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA No 20000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA015715: AB_1846278, HPA015865: " "unprognostic (1.42e-4)" "unprognostic (1.30e-3)" "unprognostic (9.01e-3)" "unprognostic (3.49e-5)" "unprognostic (4.15e-1)" "unprognostic (9.52e-4)" "unprognostic (3.68e-3)" "unprognostic (2.93e-2)" "unprognostic (3.43e-1)" "unprognostic (3.31e-3)" "unprognostic (8.36e-2)" "unprognostic (1.43e-1)" "unprognostic (2.72e-3)" "unprognostic (2.20e-1)" "unprognostic (3.91e-2)" "unprognostic (2.27e-1)" "unprognostic (3.58e-2)" 1.1 0.6 1.1 5.7 6.4 4.4 1.5 1.5 2.4 1.1 0.0 1.8 2.3 1.3 0.5 1.6 1.3 3.0 0.5 0.7 2.0 1.5 4.2 4.2 9.7 3.1 3.3 0.9 0.5 62.4 0.6 0.5 3.2 1.0 2.4 1.4 1.5 0.4 0.7 0.3 3.1 1.6 2.2 20.2 3.2 1.2 5.5 6.4 0.7 0.6 7.1 3.1 0.4 3.2 0.0 0.1 0.3 0.3 0.0 0.0 0.1 0.6 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.2 0.4 0.2 5.3 0.1 100.0 0.3 0.1 0.0 0.7 42.6 0.0 1.1 0.2 0.6 0.2 0.0 0.9 0.3 9.3 0.4 0.0 0.8 0.4 0.0 0.0 0.4 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.5 0.8 0.3 0.1 0.2 11.5 0.4 0.0 0.3 0.2 0.5 0.3 0.1 1.2 36.6 1.0 13.4 0.8 28.8 22.5 2.9 0.1 15.8 17.3 1.6 29.7 1.3 0.1 11.3 13.2 1.1 6.4 1.5 2.4 0.7 2.0 3.1 3.3 3.2 2.2 5.5 3.2 0.6 3.2 3.6 3.3 3.2 0.0 0.3 0.0 0.0 3.4 0.5 0.8 2.5 0.0 0.7 0.0 0.0 0.1 52.1 0.2 0.0 0.0 8.4 0.9 1.7 1.0 0.0 3.2 4.6 0.4 0.0 1.3 3.1 0.5 13.9 1.3 3.3 0.4 1.6 0.0 3.1 0.1 0.0 16.7 2.7 8.2 0.9 24.4 0.0 22.5 14.7 0.8 90.6 2.0 26.6 0.2 0.1 0.7 13.4 0.3 0.0 0.3 1.5 3.6 0.0 1.8 0.6 0.4 0.8 0.0 0.4 0.0 43.2 0.5 0.1 0.2 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD274 "B7-H, B7-H1, B7H1, PD-L1, PDCD1LG1, PDL1" ENSG00000120217 "CD274 molecule" Q9NZQ7 9 5450503-5470566 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 16.8" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.7;granulocytes: 28.4;Langerhans cells: 50.9;monocytes: 42.4;Syncytiotrophoblasts: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.6" "Cell line enhanced" "Detected in many" "HDLM-2: 89.6;HHSteC: 55.5;U-251 MG: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003528, CAB076385" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Actin filaments" Nucleoplasm "CAB076385: AB_2687655, HPA003528: " "prognostic favorable (8.89e-4)" "unprognostic (4.54e-2)" "prognostic favorable (1.64e-5)" "unprognostic (1.27e-2)" "unprognostic (2.96e-2)" "unprognostic (1.08e-1)" "unprognostic (4.61e-2)" "unprognostic (1.44e-1)" "unprognostic (1.68e-2)" "unprognostic (5.67e-4)" "unprognostic (7.39e-3)" "unprognostic (1.69e-2)" "unprognostic (1.24e-2)" "unprognostic (1.35e-1)" "unprognostic (1.49e-2)" "unprognostic (2.67e-1)" "unprognostic (9.02e-2)" 2.6 2.0 1.0 10.3 0.9 1.9 1.5 0.9 1.2 1.8 0.6 1.4 2.7 1.5 1.8 2.5 1.8 4.0 8.9 0.8 1.9 2.6 3.4 16.8 6.6 1.8 1.6 1.5 1.9 5.0 2.6 6.8 2.0 2.0 2.1 1.2 1.5 1.5 4.5 0.7 1.9 2.2 1.7 10.2 1.9 0.9 1.6 13.0 3.5 4.3 5.3 7.2 1.3 1.1 15.6 0.2 0.0 0.5 0.1 0.1 0.0 30.5 25.7 7.7 10.4 0.0 5.0 0.2 0.6 0.8 3.8 0.6 0.0 13.2 24.6 89.6 0.0 9.0 0.3 0.0 55.5 0.0 0.0 0.5 0.1 15.7 22.9 7.7 15.0 0.9 0.0 2.9 23.4 0.0 0.4 0.1 0.0 0.0 0.3 0.1 4.2 0.8 1.6 0.3 0.0 0.3 0.4 2.4 1.9 2.2 0.1 0.3 28.1 16.1 5.1 0.5 98.1 0.5 0.2 0.3 5.4 0.3 0.2 6.6 0.0 0.2 0.7 0.1 1.2 0.5 1.4 1.1 0.0 0.1 0.7 0.4 3.6 0.3 0.0 0.0 0.7 0.4 1.0 0.9 0.9 1.2 0.8 1.9 1.8 1.6 2.0 1.7 1.6 1.1 3.0 12.8 11.4 0.7 1.9 4.6 1.5 4.4 1.8 1.4 1.4 1.3 7.8 0.0 2.9 0.0 0.0 6.1 2.4 2.6 0.0 5.9 1.0 1.4 0.3 5.5 0.0 3.2 1.9 4.4 27.7 1.9 0.5 0.9 28.4 0.2 7.1 0.8 5.7 0.0 3.3 0.5 4.1 2.9 50.9 0.2 0.3 4.2 3.6 8.4 42.4 0.5 1.0 1.0 0.9 19.0 0.1 0.4 2.2 2.1 1.9 0.4 4.0 0.2 0.0 2.3 0.9 1.0 0.8 1.2 2.6 44.5 3.1 0.1 0.4 2.0 CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 204.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" 14.0 10.5 3.4 15.0 3.4 14.3 17.8 6.3 4.6 18.1 8.8 40.0 56.9 12.0 13.2 19.2 14.1 15.0 7.7 2.7 3.8 34.1 20.2 17.1 15.9 4.3 3.9 6.4 20.2 35.6 6.0 21.6 4.7 19.7 36.9 6.9 17.0 13.5 6.9 18.0 59.5 10.9 4.3 13.7 40.4 9.4 3.9 34.0 18.2 10.3 17.4 30.1 10.1 4.6 58.0 22.5 6.9 14.3 9.4 13.6 54.8 13.9 16.9 18.5 23.3 37.3 39.9 74.5 56.9 18.2 24.0 21.2 23.0 34.7 29.9 29.9 37.2 41.3 18.4 33.6 12.5 23.3 15.4 9.7 32.1 17.7 25.5 35.7 30.1 24.4 73.5 23.2 16.9 18.2 44.6 8.7 20.3 69.6 8.1 23.6 17.6 34.1 115.6 101.7 20.9 8.1 27.9 36.9 27.7 31.1 35.0 14.8 36.2 36.9 30.8 12.0 39.9 17.5 31.3 52.6 39.4 12.4 19.2 1.8 0.5 3.2 1.2 0.4 1.8 0.9 1.0 1.1 1.2 1.0 0.9 1.5 0.1 3.1 0.4 9.9 0.9 0.5 3.4 3.4 6.3 4.6 2.7 3.8 4.3 3.9 4.7 4.3 3.9 4.6 81.7 96.1 67.1 32.0 40.5 32.2 52.1 26.5 39.9 10.0 40.4 26.4 17.2 35.8 68.9 71.7 16.7 53.0 96.1 204.1 21.5 84.6 10.4 97.9 25.0 56.6 55.8 42.9 40.7 98.0 17.1 20.6 101.4 136.7 24.1 28.5 37.5 24.2 17.4 15.2 45.3 97.3 40.7 26.2 12.6 10.5 16.8 30.6 14.2 83.4 18.0 12.5 22.6 28.6 30.8 151.3 114.0 10.9 27.7 89.0 182.3 67.4 60.0 13.0 26.3 34.9 27.8 38.9 27.2 44.2 41.1 40.9 29.4 48.0 68.8 143.6 CD300A "CMRF-35-H9, CMRF35H, IGSF12, IRC1, IRC2, Irp60" ENSG00000167851 "CD300a molecule" Q9UGN4 17 74466399-74484794 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 95.2" "Cell type enhanced" "Detected in some" "dendritic cells: 103.5;granulocytes: 59.5;Hofbauer cells: 114.0;Kupffer cells: 97.6;Macrophages: 90.9;NK-cells: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 104.4;NB-4: 45.9;RPMI-8226: 88.7" "HPA010971, HPA011645" Approved Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Vesicles, Cytosol" "HPA010971: , HPA011645: AB_1846988" "unprognostic (1.99e-1)" "unprognostic (4.60e-2)" "unprognostic (3.88e-2)" "unprognostic (3.30e-2)" "unprognostic (2.73e-1)" "unprognostic (2.01e-1)" "unprognostic (1.04e-2)" "unprognostic (2.63e-1)" "unprognostic (1.11e-1)" "unprognostic (1.17e-2)" "unprognostic (7.87e-2)" "unprognostic (1.07e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (5.97e-2)" "unprognostic (5.45e-3)" "unprognostic (1.36e-1)" "unprognostic (5.72e-2)" 10.6 7.5 6.7 31.1 7.1 24.4 4.6 7.1 31.1 2.8 7.5 9.2 11.3 3.5 1.8 3.5 3.1 14.2 4.7 6.9 7.8 3.5 14.6 18.1 27.0 11.4 8.6 1.5 3.2 1.4 3.6 13.9 13.2 4.0 8.6 1.0 4.0 2.5 1.6 4.5 13.5 11.7 9.2 95.2 4.9 1.2 12.1 14.1 2.3 2.7 11.7 9.5 2.6 12.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 5.5 104.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.0 1.5 45.9 0.0 0.0 0.0 0.2 0.0 88.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 17.1 0.0 845.6 170.3 481.9 226.4 374.2 48.3 18.9 45.5 67.5 159.2 6.4 16.7 52.5 560.5 456.5 387.6 149.7 3.1 197.0 6.7 7.1 7.1 31.1 6.9 7.8 11.4 8.6 13.2 9.2 12.1 12.5 1.0 0.0 7.4 0.3 7.8 0.9 0.1 0.2 0.0 0.0 0.6 1.8 0.6 1.5 0.7 0.0 0.0 0.7 103.5 0.1 0.0 0.1 0.0 0.6 0.2 2.5 0.0 5.7 0.1 0.0 1.2 0.8 0.5 0.7 59.5 0.0 2.2 1.3 114.0 0.0 0.3 0.2 0.0 97.6 24.0 0.4 0.0 90.9 3.6 5.6 36.6 0.0 225.6 1.0 0.0 0.0 0.1 0.0 14.5 0.1 0.0 0.4 0.6 0.1 6.6 0.6 0.5 0.0 0.4 0.2 0.6 1.5 33.2 0.0 0.2 0.2 CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 7.8;brain: 16.3;lymphoid tissue: 8.2" "Group enriched" "Detected in some" 4 "dendritic cells: 7.1;Hofbauer cells: 6.2;Kupffer cells: 8.7;Langerhans cells: 6.5;Macrophages: 16.6;monocytes: 13.9" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 16.3" "Immune cell enhanced" "Detected in many" "eosinophil: 75.9" "Group enriched" "Detected in many" 53 "dendritic cells: 25.0;granulocytes: 75.9;monocytes: 31.7" "Group enriched" "Detected in some" 6 "HL-60: 1.7;NB-4: 2.4;THP-1: 1.9;U-937: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060449 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA060449: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (3.32e-1)" "unprognostic (2.49e-4)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (7.08e-2)" "unprognostic (4.01e-2)" 1.7 0.4 0.1 8.2 0.2 7.8 0.7 0.1 16.3 0.4 0.6 0.7 0.7 0.3 0.0 0.3 0.3 2.1 0.2 0.1 0.2 0.2 0.8 1.7 0.8 0.3 0.3 0.1 0.9 0.1 0.2 0.9 3.1 0.4 0.9 0.0 0.3 0.1 0.3 0.1 1.6 1.8 0.2 3.7 0.6 0.3 1.3 0.6 0.2 0.1 0.9 2.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 1.1 0.0 1.5 31.7 75.9 0.1 13.6 0.3 0.0 0.0 0.0 25.0 0.0 0.0 0.2 33.3 0.8 1.9 15.6 0.0 11.8 0.1 0.2 0.1 16.3 0.1 0.2 0.3 0.3 3.1 0.2 1.3 0.4 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 6.2 0.0 0.0 0.0 0.0 8.7 6.5 0.2 0.0 16.6 0.0 0.0 13.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD34 ENSG00000174059 "CD34 molecule" P28906 1 207880972-207911402 "CD markers, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Adipocytes: 298.7;Endothelial cells: 292.4;Fibroblasts: 121.9;Hepatic stellate cells: 136.0;Leydig cells: 146.3;Peritubular cells: 123.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HUVEC TERT2: 64.3;MOLT-4: 66.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000018, HPA036722, HPA036723" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 93000000 "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB000018: AB_2063006, HPA036722: AB_2675271, HPA036723: AB_2675272" "unprognostic (3.82e-1)" "unprognostic (1.67e-1)" "unprognostic (1.04e-1)" "unprognostic (3.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (5.93e-5)" "unprognostic (1.25e-2)" "unprognostic (7.74e-2)" "unprognostic (7.65e-2)" "unprognostic (3.53e-1)" "unprognostic (1.37e-3)" "unprognostic (6.95e-2)" "prognostic unfavorable (8.47e-4)" "unprognostic (1.51e-2)" "unprognostic (1.30e-1)" "unprognostic (1.60e-1)" "unprognostic (1.01e-2)" 202.7 28.5 29.2 13.9 28.8 5.7 122.3 27.3 34.2 95.4 21.0 54.2 13.5 71.6 42.3 28.9 82.8 54.3 153.2 25.1 27.5 49.4 5.6 69.1 18.1 29.8 29.5 35.4 18.9 21.8 10.1 219.5 30.8 36.2 19.3 2.3 37.4 33.2 58.5 67.5 39.3 75.5 24.8 21.7 34.4 20.2 32.9 19.0 79.5 68.2 17.1 74.0 61.6 28.0 0.0 0.0 0.2 0.0 3.2 0.3 0.2 0.4 2.4 0.7 1.7 0.0 0.0 0.0 6.2 0.7 0.2 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.3 0.0 0.7 64.3 1.1 0.0 0.0 1.7 0.0 66.5 0.3 0.5 0.0 0.0 0.1 3.7 0.0 0.3 0.0 0.1 0.2 0.0 0.6 0.1 0.4 2.3 0.0 9.9 0.2 2.8 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.2 29.2 28.8 27.3 34.2 25.1 27.5 29.8 29.5 30.8 24.8 32.9 28.0 298.7 3.2 7.8 1.6 1.0 16.7 0.2 0.3 4.6 0.6 2.1 3.0 21.9 2.8 0.1 3.7 2.1 0.2 1.5 0.0 0.0 0.5 11.6 1.0 5.2 292.4 0.0 22.3 0.2 0.2 0.3 121.9 0.5 1.0 1.3 0.1 136.0 0.6 0.4 0.0 0.1 0.0 0.0 1.2 21.8 5.0 146.3 2.4 17.8 33.7 0.3 0.2 0.0 0.5 0.3 0.2 0.0 123.0 1.6 0.3 0.0 0.1 0.0 0.2 6.6 7.7 15.2 1.0 2.0 1.5 12.9 0.1 2.2 4.0 0.0 0.3 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD3E ENSG00000198851 "CD3e molecule" P07766 11 118304730-118316175 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "lymphoid tissue: 640.4" "Group enriched" "Detected in many" 7 "dendritic cells: 213.6;NK-cells: 154.5;T-cells: 601.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 26 "gdT-cell: 490.6;MAIT T-cell: 420.8;memory CD4 T-cell: 414.4;memory CD8 T-cell: 463.5;naive CD4 T-cell: 491.7;naive CD8 T-cell: 501.3;NK-cell: 202.2;T-reg: 426.3" "Group enriched" "Detected in all" 21 "NK-cells: 202.2;T-cells: 501.3" "Group enriched" "Detected in some" 67 "JURKAT: 544.9;MOLT-4: 764.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB000010, HPA040957, HPA043955, CAB072863, CAB072864" Enhanced Supported "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Endoplasmic reticulum, Plasma membrane" "Golgi apparatus" "CAB000010: AB_2631163, CAB072863: AB_2665707, CAB072864: AB_2665708, HPA040957: AB_2677222, HPA043955: AB_2678747" "prognostic favorable (1.72e-4)" "prognostic favorable (1.62e-4)" "unprognostic (1.51e-2)" "prognostic favorable (2.30e-6)" "unprognostic (4.31e-2)" "prognostic favorable (1.32e-4)" "unprognostic (3.60e-3)" "unprognostic (3.85e-2)" "prognostic favorable (1.18e-4)" "unprognostic (6.11e-3)" "unprognostic (1.59e-1)" "unprognostic (3.59e-1)" "prognostic unfavorable (1.12e-5)" "unprognostic (5.46e-2)" "unprognostic (9.28e-2)" "unprognostic (3.13e-2)" "unprognostic (1.12e-2)" 6.4 5.6 0.9 85.8 1.1 36.7 6.7 0.9 1.2 7.1 1.3 15.3 22.0 5.8 4.6 9.5 5.4 20.1 3.8 0.7 1.0 3.5 9.7 23.0 209.6 1.8 0.9 3.8 2.2 0.7 1.0 1.6 1.4 6.6 19.3 0.0 11.6 3.0 1.9 5.4 36.4 5.1 1.2 78.9 24.4 1.7 1.3 640.4 5.3 1.6 147.0 24.8 4.9 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 544.9 0.9 2.0 0.0 0.0 764.9 0.6 0.3 0.0 0.0 0.2 0.1 1.0 0.0 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.0 1.6 8.0 9.8 0.0 0.6 0.0 16.4 1.8 2.4 490.6 1.3 420.8 1.6 414.4 463.5 1.5 2.1 491.7 501.3 12.2 202.2 2.0 8.6 426.3 333.0 0.9 1.1 0.9 1.2 0.7 1.0 1.8 0.9 1.4 1.2 1.3 1.6 4.9 0.0 8.6 0.0 12.9 5.2 0.3 0.0 0.0 0.0 3.8 4.8 0.3 0.0 0.6 1.8 0.0 0.2 213.6 0.4 0.0 0.2 7.0 0.5 0.9 2.5 0.0 6.9 0.1 0.0 0.0 5.3 24.5 0.9 7.6 0.0 8.9 2.4 0.3 0.0 0.1 0.0 0.0 7.6 8.3 0.2 0.0 12.6 12.4 1.0 8.4 0.0 154.5 0.0 0.1 0.0 1.1 0.0 41.4 0.1 0.2 2.1 0.0 0.0 0.0 1.3 2.7 0.0 0.0 1.6 5.4 0.3 601.4 0.0 0.6 0.3 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.9;lymphoid tissue: 219.3;parathyroid gland: 173.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 278.8;Hofbauer cells: 139.3;Kupffer cells: 247.1;Langerhans cells: 80.1;Macrophages: 109.0;monocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.3;intermediate monocyte: 241.4;memory CD4 T-cell: 153.4;myeloid DC: 166.3;naive CD4 T-cell: 128.1;non-classical monocyte: 204.2;plasmacytoid DC: 263.8;T-reg: 154.5" "Group enriched" "Detected in many" 20 "dendritic cells: 263.8;monocytes: 247.3;T-cells: 154.5" "Group enriched" "Detected in some" 6 "HEL: 103.2;HL-60: 42.1;NB-4: 60.0;THP-1: 116.2;U-937: 109.7" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB000011: AB_442062, CAB068180: AB_2665653, HPA004252: AB_1078466, HPA004472: AB_1078465" "unprognostic (1.39e-2)" "unprognostic (1.12e-2)" "unprognostic (2.75e-2)" "prognostic favorable (2.16e-4)" "unprognostic (7.76e-2)" "unprognostic (4.82e-3)" "unprognostic (3.70e-2)" "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.06e-1)" "unprognostic (4.65e-3)" "unprognostic (9.08e-3)" "unprognostic (2.95e-1)" 45.5 16.2 15.0 82.1 15.4 26.5 14.7 15.5 17.4 20.4 15.8 26.0 18.7 7.9 7.0 15.1 21.3 35.3 10.0 15.1 16.7 10.1 152.9 72.1 119.0 22.9 20.2 8.6 7.6 173.8 6.1 47.4 21.0 7.3 31.0 10.5 8.5 10.3 2.9 12.6 27.4 26.5 19.6 164.4 21.0 7.5 19.6 219.3 8.8 5.7 75.7 41.0 5.8 25.7 0.0 0.0 3.6 0.1 0.1 0.2 0.3 0.1 2.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 103.2 0.0 0.6 10.5 42.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 15.4 60.0 1.0 0.0 0.0 0.0 0.2 12.8 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.7 0.1 116.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.1 109.7 0.0 0.8 247.3 1.9 2.0 241.4 6.3 0.5 153.4 0.8 166.3 0.5 128.1 0.7 11.1 2.0 204.2 263.8 154.5 240.6 15.0 15.4 15.5 17.4 15.1 16.7 22.9 20.2 21.0 19.6 19.6 25.7 4.5 0.0 5.2 1.6 5.2 3.4 0.3 0.4 0.0 1.5 2.9 5.8 2.1 8.6 2.1 3.7 0.0 0.9 61.9 0.0 5.9 0.0 0.1 3.5 8.7 9.6 0.0 7.8 0.9 0.4 1.2 3.7 0.0 0.4 7.6 0.4 278.8 34.3 139.3 5.0 0.7 0.0 0.0 247.1 80.1 0.5 16.8 109.0 5.4 29.0 104.5 22.0 6.2 0.5 0.2 0.0 0.0 15.1 2.5 0.2 0.0 3.3 20.3 0.2 13.1 0.7 13.5 0.0 0.2 0.4 2.3 1.2 34.0 0.0 0.0 0.4 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752054-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 296.7;eosinophil: 382.4;neutrophil: 401.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 401.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" 98.6 237.4 30.0 64.0 35.0 80.5 128.4 33.5 39.5 74.0 61.4 103.1 124.6 62.1 77.1 102.2 110.0 73.8 64.9 30.2 34.4 173.2 133.9 129.1 58.2 37.4 33.6 61.2 112.5 310.6 41.8 221.5 38.1 167.4 103.2 72.6 166.9 107.4 47.4 47.7 98.6 67.1 34.8 79.6 117.4 40.5 36.3 44.4 86.8 58.1 66.6 97.2 68.2 41.5 130.0 71.7 66.1 30.8 202.9 199.2 99.9 95.0 137.3 61.3 82.5 71.3 335.4 19.8 94.3 95.3 84.5 170.7 50.0 130.5 93.0 99.9 70.9 42.9 73.8 128.6 128.8 94.8 142.8 172.9 189.6 92.9 72.5 144.4 174.2 76.8 91.8 83.4 95.7 61.3 45.4 82.8 75.6 76.9 70.9 30.2 104.7 123.0 251.4 252.6 66.5 45.4 120.5 266.8 160.1 130.8 210.2 79.8 150.9 65.6 57.7 139.2 109.9 111.2 144.3 60.1 95.8 61.2 63.0 296.7 79.8 382.4 50.1 82.4 68.9 43.5 63.3 55.8 47.3 34.1 71.1 60.5 401.8 46.9 87.5 24.9 60.5 102.4 30.0 35.0 33.5 39.5 30.2 34.4 37.4 33.6 38.1 34.8 36.3 41.5 186.0 201.9 241.1 59.7 60.3 52.9 89.3 87.2 108.1 63.0 144.3 85.7 61.4 75.8 177.8 145.3 66.7 247.3 94.0 105.2 15.6 77.4 227.7 206.1 67.0 106.7 72.8 46.9 61.0 79.9 76.2 70.5 97.9 231.3 114.5 78.1 77.8 120.9 59.9 40.4 73.6 91.1 87.5 78.9 63.1 36.9 47.2 91.6 62.2 82.4 88.7 25.3 39.1 112.1 153.9 72.8 117.7 44.0 76.0 144.5 92.6 54.4 208.8 87.3 52.6 69.7 89.3 17.1 20.2 104.5 45.9 343.7 89.9 99.4 115.9 165.7 CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 589.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" 51.8 64.9 39.2 116.4 47.9 232.2 89.3 64.4 63.5 57.4 30.4 89.0 74.6 53.0 92.4 93.9 100.5 86.7 59.5 47.2 41.9 44.4 71.4 154.6 137.9 53.1 40.5 46.1 41.5 27.2 34.6 80.1 48.5 122.2 99.3 285.7 105.3 55.7 57.9 59.8 79.3 55.4 50.9 100.1 104.2 59.0 49.2 79.1 91.2 22.8 161.7 110.1 52.4 76.4 303.3 49.9 108.0 62.1 130.3 122.6 147.9 106.0 139.4 70.8 126.0 2.1 159.1 129.6 180.0 90.7 216.5 201.0 52.2 98.7 91.7 81.5 35.8 311.6 45.9 3.9 73.8 227.4 467.6 85.7 58.1 71.6 53.6 118.5 73.4 132.6 85.1 323.6 108.5 148.1 268.5 77.0 46.7 298.4 133.6 154.2 69.3 187.8 185.3 115.8 69.7 37.9 63.6 111.7 124.4 56.5 227.4 85.8 76.5 210.9 40.9 120.7 79.4 124.2 100.8 208.0 131.5 119.8 65.6 185.2 119.2 232.8 178.1 244.2 155.6 191.6 209.7 192.0 181.6 188.7 149.2 169.0 145.4 232.6 339.2 133.3 334.5 296.9 39.2 47.9 64.4 63.5 47.2 41.9 53.1 40.5 48.5 50.9 49.2 76.4 72.3 368.6 157.4 98.6 192.9 165.3 311.7 504.4 101.3 102.9 119.0 93.1 51.9 110.1 205.7 93.8 95.9 169.9 218.6 36.5 15.6 589.6 81.5 157.2 17.0 76.5 63.8 112.6 219.2 412.5 85.5 119.1 36.2 120.4 57.7 250.0 83.6 34.2 186.4 122.8 129.3 70.8 148.5 79.6 200.7 52.2 34.2 121.5 117.4 39.4 100.5 51.7 219.4 107.1 150.4 344.7 92.6 48.5 143.8 439.0 53.7 16.3 162.2 229.7 65.7 47.1 85.4 111.5 19.6 97.1 140.1 121.2 160.8 80.6 94.3 321.3 CD48 "BCM1, BLAST, hCD48, mCD48, SLAMF2" ENSG00000117091 "CD48 molecule" P09326 1 160678746-160711831 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 148.4;lymphoid tissue: 283.9" "Cell type enhanced" "Detected in many" "B-cells: 336.1;dendritic cells: 251.2;Kupffer cells: 245.8;Macrophages: 218.3;monocytes: 366.6;NK-cells: 454.2;T-cells: 376.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 220.9;HMC-1: 236.9;U-266/70: 501.4;U-266/84: 360.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002497, HPA055146" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 2000000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoli fibrillar center, Cytosol" "CAB002497: AB_563586, HPA055146: AB_2682716" "prognostic favorable (3.91e-4)" "unprognostic (1.72e-3)" "prognostic favorable (4.17e-4)" "unprognostic (1.58e-3)" "unprognostic (2.36e-1)" "unprognostic (1.71e-3)" "unprognostic (2.09e-2)" "unprognostic (2.19e-2)" "unprognostic (1.92e-1)" "unprognostic (3.02e-2)" "unprognostic (1.38e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (3.36e-4)" "unprognostic (3.21e-1)" "unprognostic (4.69e-2)" "unprognostic (9.38e-2)" "unprognostic (8.51e-2)" 11.8 5.9 1.4 115.3 1.5 148.4 18.8 1.5 4.7 10.2 2.3 24.9 20.5 6.7 5.0 8.4 5.7 26.6 4.3 1.3 1.7 4.4 19.9 31.0 283.9 2.6 1.8 3.1 2.0 1.6 1.6 5.8 2.7 8.1 32.5 0.1 14.0 4.4 2.9 3.5 48.3 12.5 2.1 160.0 32.5 2.9 3.2 138.9 5.2 3.4 256.8 41.8 4.5 4.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 220.9 0.1 0.0 0.0 0.5 0.1 0.0 0.0 6.0 0.0 2.1 0.0 0.0 0.0 27.1 236.9 0.0 0.0 0.0 0.0 0.0 0.0 23.1 0.4 78.6 0.0 0.0 78.9 38.4 0.1 0.0 0.0 4.7 0.1 34.3 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.5 0.1 0.0 0.3 0.2 0.4 501.4 360.3 89.9 0.2 66.7 0.1 218.1 327.1 230.8 242.8 470.2 335.8 206.2 275.2 283.4 329.7 161.2 277.9 301.6 82.1 160.7 487.4 57.0 229.9 603.5 1.4 1.5 1.5 4.7 1.3 1.7 2.6 1.8 2.7 2.1 3.2 4.1 3.7 0.0 9.6 0.7 336.1 5.5 0.8 0.0 1.8 0.0 2.0 1.7 1.1 2.8 1.3 3.7 0.0 0.6 251.2 0.1 1.9 0.2 0.1 0.7 0.5 2.8 1.2 21.5 0.1 0.2 0.8 2.4 6.6 0.6 90.7 0.1 7.1 2.0 86.4 0.0 0.1 0.1 0.0 245.8 106.5 0.5 1.8 218.3 39.2 1.0 366.6 0.0 454.2 0.5 0.0 0.1 0.0 0.4 127.4 0.4 0.0 4.9 2.2 0.0 0.0 1.7 2.1 0.5 0.3 0.7 3.0 0.4 376.2 0.0 1.2 0.5 CD79B "B29, IGB" ENSG00000007312 "CD79b molecule" P40259 17 63928740-63932336 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 266.7" "Cell type enriched" "Detected in many" 4 "B-cells: 491.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 4 "memory B-cell: 1132.1;naive B-cell: 1505.8" "Lineage enriched" "Detected in all" 5 "B-cells: 1505.8" "Cell line enhanced" "Detected in some" "Daudi: 1060.0;REH: 350.2;U-698: 1475.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009178, CAB009751, HPA044107" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009751: AB_2275844, HPA009178: AB_1078483, HPA044107: " "unprognostic (3.90e-3)" "unprognostic (1.61e-3)" "unprognostic (5.21e-2)" "unprognostic (3.45e-3)" "unprognostic (4.22e-3)" "prognostic favorable (2.35e-4)" "unprognostic (1.82e-1)" "unprognostic (9.25e-3)" "unprognostic (3.89e-2)" "unprognostic (1.48e-1)" "unprognostic (1.04e-1)" "unprognostic (2.87e-2)" "unprognostic (2.50e-3)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (4.28e-2)" "unprognostic (2.75e-1)" 5.0 1.7 0.9 70.5 0.9 54.6 3.4 0.9 1.4 1.9 1.7 7.7 4.7 1.4 1.6 2.6 1.5 6.8 12.3 0.9 0.9 4.7 3.4 4.9 266.7 1.0 0.9 0.6 0.7 0.7 25.3 3.8 0.9 2.5 7.2 0.0 7.8 0.8 3.4 2.4 66.2 2.6 0.9 147.7 10.7 1.0 1.0 27.1 4.1 5.8 208.4 13.4 2.2 1.0 1.8 0.0 0.5 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.4 0.0 0.0 1060.0 7.8 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.0 2.7 0.0 0.4 0.6 0.6 0.5 0.0 0.0 0.1 0.0 0.0 1.2 0.4 1.2 56.9 0.0 0.0 0.6 23.0 0.3 0.0 0.0 350.2 0.9 4.4 0.0 0.0 0.5 0.0 1.7 0.0 0.7 5.8 0.0 16.2 1.7 0.1 3.7 0.3 0.6 51.3 54.4 1475.5 0.0 2.2 0.0 6.2 13.0 1.1 44.9 192.2 51.3 1132.1 57.1 30.1 47.0 1505.8 38.4 23.2 5.8 42.4 304.3 6.7 107.9 112.1 0.9 0.9 0.9 1.4 0.9 0.9 1.0 0.9 0.9 0.9 1.0 1.0 24.9 0.0 1.3 0.0 491.9 4.5 0.4 0.0 1.8 0.0 1.1 4.4 1.4 1.5 0.0 0.0 0.0 0.2 24.2 0.3 0.0 0.1 0.6 0.3 1.0 25.2 1.2 8.6 0.0 0.0 0.4 3.3 0.5 0.3 15.2 0.0 51.4 1.3 5.8 0.0 0.0 0.4 0.0 14.8 5.1 1.4 1.2 13.4 21.4 0.0 14.3 0.0 36.0 0.0 0.0 0.0 0.1 1.9 99.6 0.4 0.0 1.0 0.0 0.0 0.0 4.4 5.4 1.2 0.3 0.7 3.1 0.4 27.0 0.5 0.8 0.2 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA039404: AB_10673530, HPA040787: AB_2677137" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.17e-2)" "unprognostic (9.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (9.20e-3)" "unprognostic (2.04e-1)" 4.0 5.0 2.1 3.6 2.2 8.1 4.3 4.3 3.1 7.7 3.2 4.5 2.8 5.9 4.4 4.1 6.1 2.5 2.9 2.1 0.9 3.2 4.0 3.5 4.2 3.0 1.5 11.3 4.8 3.5 5.1 3.2 2.7 6.9 2.5 2.6 5.4 3.5 4.2 4.9 4.2 2.8 0.7 4.6 4.5 6.3 1.4 5.2 5.1 2.8 3.4 5.8 5.6 2.6 8.1 5.4 7.2 10.4 6.3 5.4 8.6 10.4 4.3 9.9 7.2 13.6 4.2 3.9 11.2 5.8 9.7 15.5 7.7 4.7 2.9 9.9 7.2 14.5 10.3 5.3 4.7 10.8 13.2 7.4 5.2 6.3 4.5 6.1 7.6 13.0 18.9 5.7 8.2 4.5 8.4 14.2 3.6 7.7 8.5 11.9 9.0 3.4 3.1 7.9 5.9 6.8 8.2 11.3 1.7 4.6 8.6 15.9 5.6 10.4 9.2 8.6 12.1 11.2 12.7 8.7 5.4 15.8 8.6 1.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.1 2.2 4.3 3.1 2.1 0.9 3.0 1.5 2.7 0.7 1.4 2.6 2.0 0.0 3.7 4.6 2.4 1.9 2.0 1.5 1.8 3.3 3.2 1.8 2.2 2.8 1.5 7.3 4.2 3.0 2.6 1.9 0.0 1.5 0.4 2.0 2.8 2.3 4.8 1.7 7.6 1.8 1.6 2.9 3.6 2.0 1.3 9.0 3.9 3.6 2.1 1.7 6.3 1.6 4.1 2.5 0.9 1.2 4.4 1.6 0.0 4.7 1.5 4.5 2.1 5.5 3.8 1.6 0.5 4.9 2.5 2.3 2.2 1.3 1.9 4.7 19.7 3.4 2.4 5.4 2.1 2.8 1.3 2.2 2.5 4.6 2.6 1.7 CDC42EP1 "Borg5, CEP1, MSE55" ENSG00000128283 "CDC42 effector protein 1" Q00587 22 37560480-37569405 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 245.6;Exocrine glandular cells: 226.0;Pancreatic endocrine cells: 266.2;Urothelial cells: 161.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "classical monocyte: 7.3;intermediate monocyte: 1.9;myeloid DC: 2.4" "Group enriched" "Detected in many" 10 "dendritic cells: 2.4;monocytes: 7.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006379, HPA076536" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA006379: AB_1078486, HPA076536: " "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (2.44e-1)" "unprognostic (3.79e-3)" "unprognostic (5.82e-2)" "unprognostic (4.06e-2)" "unprognostic (4.38e-2)" "unprognostic (5.57e-2)" "unprognostic (9.45e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.85e-2)" "unprognostic (3.81e-2)" "unprognostic (1.09e-3)" 76.3 91.2 55.7 16.7 107.5 1.6 58.0 89.9 73.3 68.2 17.6 43.7 31.1 70.7 4.1 93.1 61.0 40.8 53.8 55.9 67.3 50.2 133.1 65.2 11.3 102.8 104.5 60.9 161.6 16.5 18.8 31.8 97.4 41.5 14.4 2.6 102.7 23.9 13.1 71.2 32.7 19.6 70.2 26.2 155.9 23.6 87.5 2.7 33.7 11.1 10.4 38.4 69.6 151.5 125.2 35.4 15.1 67.9 23.7 40.2 73.3 69.9 41.0 78.9 54.3 87.8 15.9 0.2 24.2 81.4 25.4 95.0 17.8 35.1 26.0 15.5 60.7 0.5 33.9 53.6 167.7 0.3 0.6 74.9 52.1 65.0 61.5 63.1 59.2 0.1 78.9 0.7 33.0 42.6 0.3 0.5 13.6 96.5 79.6 0.4 27.5 2.4 27.9 1.9 0.4 2.6 51.2 112.3 112.4 20.6 50.3 11.0 91.6 163.9 98.2 80.0 98.6 0.2 0.8 0.3 65.3 0.7 135.6 0.4 7.3 0.0 0.1 1.9 0.1 0.0 0.1 0.1 2.4 0.3 0.0 0.2 0.2 0.4 0.1 0.3 0.0 3.4 55.7 107.5 89.9 73.3 55.9 67.3 102.8 104.5 97.4 70.2 87.5 151.5 62.4 6.4 19.5 2.3 1.8 46.9 87.2 51.4 21.1 0.1 59.2 31.8 3.5 134.4 41.1 12.9 0.0 98.2 2.0 41.6 1.9 245.6 3.7 4.3 20.0 54.7 11.5 0.0 0.1 226.0 110.3 32.1 133.0 9.0 2.5 1.7 69.7 35.6 13.2 1.7 0.2 66.6 30.5 5.9 29.3 1.7 39.4 5.3 21.4 4.7 8.9 12.8 0.0 2.0 42.7 266.2 45.8 35.3 0.6 122.4 17.5 11.4 14.7 0.3 39.5 22.8 49.5 2.0 0.6 55.9 52.0 112.2 2.2 7.0 61.1 161.3 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDC42EP4 "BORG4, CEP4, KAIA1777, MGC17125, MGC3740" ENSG00000179604 "CDC42 effector protein 4" Q9H3Q1 17 73283624-73312005 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Horizontal cells: 753.7;Muller glia cells: 570.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 20.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023335, HPA024797" Approved Supported Supported "Plasma membrane,Actin filaments,Microtubules" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Microtubules" "Plasma membrane" "HPA023335: AB_10603783, HPA024797: AB_10600696" "unprognostic (8.76e-2)" "unprognostic (4.38e-3)" "unprognostic (1.49e-2)" "unprognostic (5.43e-3)" "unprognostic (6.29e-2)" "unprognostic (9.01e-3)" "unprognostic (2.44e-3)" "unprognostic (1.08e-1)" "unprognostic (8.00e-2)" "unprognostic (2.41e-1)" "unprognostic (4.16e-2)" "unprognostic (6.73e-2)" "unprognostic (3.97e-1)" "unprognostic (1.66e-1)" "unprognostic (1.54e-1)" "unprognostic (1.10e-1)" "unprognostic (1.94e-1)" 94.5 54.9 84.9 15.3 84.7 14.9 74.5 90.6 76.3 47.4 75.0 55.6 35.7 52.7 60.1 33.3 69.4 19.1 50.5 82.2 103.1 28.6 32.2 38.6 16.1 141.9 104.5 70.7 77.5 20.5 45.0 22.9 83.7 38.7 17.4 98.1 41.5 43.1 28.8 40.6 36.0 25.5 103.5 24.1 42.4 20.5 105.9 20.2 45.4 18.8 27.6 33.8 39.5 109.5 30.1 70.1 24.7 20.9 48.8 40.5 65.0 26.2 32.6 24.3 17.9 14.8 42.1 0.1 22.9 31.6 27.6 20.6 17.2 18.0 14.6 1.4 17.0 6.7 35.2 34.7 24.3 1.1 7.3 51.4 14.9 21.2 10.5 19.2 27.9 0.6 18.9 1.4 14.9 23.2 1.2 8.6 13.5 87.8 48.4 0.8 11.0 3.1 28.8 34.3 16.4 24.8 19.7 53.1 18.4 19.0 64.3 9.8 28.7 22.7 47.6 18.1 18.9 1.4 1.2 0.2 37.3 4.7 60.7 3.3 3.2 5.9 0.1 8.5 0.2 0.1 0.0 0.0 4.3 0.0 0.2 0.0 5.4 0.3 20.1 0.1 0.0 2.1 84.9 84.7 90.6 76.3 82.2 103.1 141.9 104.5 83.7 103.5 105.9 109.5 117.1 12.8 15.6 54.9 2.8 48.7 58.5 54.9 97.9 11.5 45.8 37.1 10.8 31.5 29.1 12.9 6.2 32.1 2.5 47.3 11.7 29.4 0.6 29.7 47.6 43.8 31.2 9.1 1.0 43.6 35.0 46.1 31.1 41.2 13.3 19.6 42.8 27.7 6.1 753.7 1.3 41.3 14.2 5.5 30.1 2.7 18.3 9.1 30.2 6.5 11.1 570.4 0.0 2.5 2.5 30.4 33.5 15.4 2.5 42.6 53.1 8.0 18.0 26.2 131.5 98.0 69.9 1.1 2.0 83.2 44.9 84.3 6.0 13.6 30.2 124.1 CDC42SE1 "SCIP1, SPEC1" ENSG00000197622 "CDC42 small effector 1" Q9NRR8 1 151050971-151070325 "Predicted intracellular proteins" "Cell shape, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 320.7;NK-cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 453.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027634 Approved Supported "Cell Junctions" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Cell Junctions" "HPA027634: AB_10600861" "unprognostic (1.59e-2)" "unprognostic (5.76e-2)" "unprognostic (8.93e-3)" "unprognostic (4.61e-3)" "unprognostic (1.63e-1)" "unprognostic (5.76e-2)" "unprognostic (2.85e-2)" "unprognostic (1.71e-1)" "unprognostic (6.96e-3)" "unprognostic (2.19e-1)" "unprognostic (2.59e-2)" "unprognostic (3.04e-1)" "prognostic unfavorable (2.19e-6)" "unprognostic (9.94e-2)" "unprognostic (4.89e-2)" "unprognostic (2.86e-3)" "unprognostic (4.12e-2)" 54.4 48.0 39.2 63.8 40.7 81.6 41.9 41.0 48.7 46.0 38.1 40.2 20.0 35.0 26.8 97.4 44.0 37.2 44.8 38.8 40.5 59.2 30.0 73.2 84.3 43.1 42.2 44.0 36.5 71.5 37.2 48.6 43.7 56.1 33.7 20.6 54.1 33.2 21.9 61.6 58.7 37.3 42.9 122.3 44.6 11.1 43.2 56.4 46.0 19.2 84.5 65.7 64.1 44.1 61.5 28.5 48.4 30.5 37.0 35.5 73.9 45.6 47.1 51.1 43.5 27.6 64.3 44.2 36.2 51.3 27.4 74.9 51.6 79.8 44.6 69.9 27.7 71.6 30.2 13.6 49.1 64.1 110.0 39.8 125.7 64.3 49.6 71.8 64.6 43.9 114.1 100.8 58.2 91.3 46.8 46.1 54.5 56.2 30.5 41.1 40.8 49.6 64.5 97.2 20.7 49.3 39.4 83.6 82.8 75.9 93.1 113.1 61.7 49.5 36.6 38.5 84.2 65.6 56.1 453.9 35.8 47.8 111.8 124.6 43.9 228.5 88.5 80.7 70.0 44.0 75.5 81.0 58.3 44.9 62.9 78.4 369.7 91.1 82.7 21.9 123.2 38.1 39.2 40.7 41.0 48.7 38.8 40.5 43.1 42.2 43.7 42.9 43.2 44.1 76.4 38.5 56.2 22.2 110.5 66.2 54.4 41.0 42.1 28.3 94.1 64.1 8.1 27.1 44.8 55.2 25.0 57.9 320.7 36.1 21.5 41.3 85.0 23.4 38.0 50.5 35.3 24.4 30.5 37.0 72.1 40.0 33.1 35.1 71.7 19.0 65.0 33.9 73.2 26.9 29.1 29.9 50.8 138.8 204.1 16.6 11.5 115.0 55.2 32.8 159.8 23.0 233.8 36.7 44.9 66.7 39.3 24.0 93.8 41.9 19.4 27.5 21.8 24.2 32.9 47.9 46.5 35.0 18.7 59.6 93.6 114.8 142.7 22.2 21.4 73.4 CDCA4 "FLJ20764, Hepp" ENSG00000170779 "Cell division cycle associated 4" Q9BXL8 14 105009573-105021083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 55.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 64.2;Cytotrophoblasts: 84.5;Extravillous trophoblasts: 154.5;Spermatogonia: 69.9;Suprabasal keratinocytes: 67.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA064971 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 16: MAIT-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA064971: AB_2685395" "unprognostic (2.22e-3)" "unprognostic (1.84e-1)" "unprognostic (2.69e-1)" "unprognostic (9.93e-3)" "unprognostic (1.42e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (4.19e-4)" "prognostic unfavorable (7.94e-4)" "unprognostic (4.20e-2)" "unprognostic (8.54e-2)" "prognostic unfavorable (6.67e-4)" "unprognostic (6.73e-2)" "prognostic unfavorable (1.47e-6)" "unprognostic (2.15e-1)" "unprognostic (1.55e-1)" "unprognostic (7.50e-2)" "unprognostic (1.24e-2)" 3.9 2.6 1.9 7.4 2.0 55.8 4.2 3.0 2.1 8.7 2.1 4.6 4.7 5.4 1.8 18.6 4.1 2.6 2.7 1.7 1.8 3.4 2.7 3.6 11.6 2.1 1.9 4.1 3.2 1.8 1.7 9.2 2.1 3.8 2.9 1.3 5.5 2.2 1.4 24.7 4.9 3.5 1.9 6.6 3.8 11.6 2.0 14.6 3.3 1.5 8.5 4.2 10.2 2.0 40.6 41.3 46.7 35.6 7.9 13.2 61.1 59.0 18.0 45.2 39.7 50.9 50.2 52.9 31.5 20.9 34.5 63.5 32.9 68.0 27.1 58.2 26.1 33.4 33.9 43.2 9.7 59.8 27.0 9.4 20.8 35.2 32.7 15.1 31.4 45.0 37.5 53.0 32.1 98.8 56.2 40.1 34.8 35.1 94.0 53.6 68.1 19.7 15.9 46.2 27.2 33.5 56.6 22.3 46.8 20.5 44.0 39.8 48.8 39.9 50.5 55.3 79.5 19.5 25.9 54.4 33.5 30.2 67.5 1.1 4.3 10.6 11.9 4.9 14.8 8.4 12.7 16.7 4.7 5.4 7.4 8.9 1.6 12.9 5.6 5.1 11.1 7.0 1.9 2.0 3.0 2.1 1.7 1.8 2.1 1.9 2.1 1.9 2.0 2.0 5.4 0.0 2.2 0.7 7.4 64.2 26.5 36.6 13.1 3.4 8.7 8.3 0.6 0.0 9.0 1.8 0.0 84.5 11.5 4.3 3.9 12.7 8.1 9.0 9.0 10.9 3.0 53.0 1.8 7.0 154.5 10.2 3.1 12.5 28.6 15.1 7.9 2.2 24.3 13.5 1.3 6.6 6.1 5.9 22.6 6.8 8.4 8.4 17.8 2.8 9.3 4.6 9.2 1.0 1.8 12.3 3.3 6.0 11.8 16.1 1.9 1.8 7.7 2.6 6.6 4.6 12.5 43.0 69.9 21.3 67.1 25.9 17.7 3.6 9.5 43.2 CDH1 "CD324, UVO, uvomorulin" ENSG00000039068 "Cadherin 1" P12830 16 68737292-68835537 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 197.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 451.6;Glandular and luminal cells: 321.0;Pancreatic endocrine cells: 264.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 13 "myeloid DC: 1.7;plasmacytoid DC: 4.7" "Lineage enriched" "Detected in single" 19 "dendritic cells: 4.7" "Cell line enhanced" "Detected in many" "BEWO: 683.3;CACO-2: 241.9;CAPAN-2: 328.1;HaCaT: 318.7;hTCEpi: 217.2;MCF7: 199.6;OE19: 207.2;RT4: 237.7;T-47d: 209.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000087, HPA004812, CAB028364, CAB072855, CAB072856, CAB072857" Enhanced Supported "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA 78000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Golgi apparatus" "CAB000087: AB_2533003, CAB028364: AB_2076812, CAB072855: AB_2665698, CAB072856: AB_2665699, CAB072857: AB_2665700, HPA004812: AB_1078369" "unprognostic (3.95e-2)" "unprognostic (1.91e-1)" "unprognostic (1.12e-3)" "unprognostic (1.13e-1)" "unprognostic (1.42e-1)" "unprognostic (2.78e-1)" "unprognostic (5.04e-3)" "unprognostic (1.63e-1)" "unprognostic (5.47e-2)" "unprognostic (2.85e-1)" "unprognostic (1.19e-2)" "unprognostic (3.61e-1)" "prognostic favorable (2.06e-4)" "unprognostic (1.21e-1)" "unprognostic (2.62e-1)" "unprognostic (2.51e-1)" "unprognostic (5.92e-2)" 1.0 0.2 1.5 16.1 2.0 6.5 64.2 0.6 1.9 30.0 19.3 127.5 133.9 9.6 39.5 76.9 51.5 45.7 0.3 1.5 1.3 39.8 97.2 36.8 5.6 2.0 1.3 1.3 84.0 197.8 8.0 60.9 1.3 91.7 131.0 0.1 71.9 41.7 0.3 107.7 127.9 5.1 2.1 10.3 104.2 0.4 2.3 20.1 162.7 0.1 29.0 58.2 38.1 2.7 147.0 14.8 0.0 0.5 0.0 0.0 683.3 0.0 0.0 0.0 0.0 241.9 328.1 0.0 3.1 0.0 0.0 318.7 0.0 156.3 0.0 28.6 3.5 0.1 0.7 48.0 0.0 0.0 0.6 0.0 217.2 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 199.6 0.2 1.0 5.5 207.2 0.8 0.1 0.1 2.1 53.9 237.7 8.5 0.8 1.4 0.2 58.9 91.8 209.2 0.4 0.0 0.4 0.9 0.7 0.6 0.1 0.3 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.2 0.0 4.7 0.0 0.1 1.5 2.0 0.6 1.9 1.5 1.3 2.0 1.3 1.3 2.1 2.3 2.7 0.6 131.4 69.8 0.7 1.4 94.1 130.3 73.8 45.5 0.0 137.6 83.6 0.9 128.7 95.3 163.7 0.0 117.6 2.5 451.6 1.9 129.1 0.1 159.3 29.2 4.4 86.7 9.0 0.7 113.5 29.6 3.4 132.0 321.0 1.3 2.8 0.4 63.4 11.7 0.0 1.4 208.3 75.3 1.2 13.4 0.0 0.3 3.2 53.4 1.0 3.3 0.0 0.0 0.5 32.1 264.6 204.6 0.4 2.2 195.5 159.5 4.5 118.2 0.0 0.0 0.0 7.1 0.1 0.1 100.6 131.6 50.5 2.7 0.0 154.8 251.5 CDH10 ENSG00000040731 "Cadherin 10" Q9Y6N8 5 24487100-24644978 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 13.0;prostate: 4.4" "Group enriched" "Detected in some" 20 "Astrocytes: 169.4;Excitatory neurons: 423.4;Inhibitory neurons: 216.9;Oligodendrocyte precursor cells: 488.6" "Cancer enriched" "Detected in some" 4 "glioma: 5.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 7.1;HAP1: 4.6;hTERT-RPE1: 4.2;SuSa: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010651, HPA012085" Approved Approved "Nucleoplasm,Cell Junctions" NA NA 270000 "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA010651: AB_1078370, HPA012085: " "unprognostic (4.31e-3)" "unprognostic (2.77e-1)" "unprognostic (1.88e-1)" "unprognostic (3.66e-2)" "unprognostic (4.48e-1)" "unprognostic (6.11e-3)" "unprognostic (6.27e-2)" "unprognostic (1.59e-7)" "unprognostic (1.65e-2)" "unprognostic (1.41e-1)" "unprognostic (8.74e-3)" 0.0 0.7 5.6 0.0 8.4 0.0 0.1 13.0 8.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 9.0 0.9 0.0 0.0 0.1 0.0 0.3 1.7 0.0 0.1 0.0 0.4 0.0 2.2 4.4 0.2 1.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.3 1.1 0.0 0.0 1.1 0.0 0.0 0.1 4.6 0.0 0.0 7.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.1 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 11.7 0.0 0.0 0.0 1.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.4 13.0 8.7 9.0 0.9 0.3 1.7 2.2 1.2 1.1 4.6 0.0 0.0 0.0 169.4 0.0 0.1 0.0 0.0 0.0 2.3 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.1 0.4 0.1 0.0 0.0 423.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 216.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 15.9 0.0 0.6 0.0 488.6 7.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.1;skeletal muscle: 68.6;tongue: 57.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 328.8;Inhibitory neurons: 867.0;Oligodendrocyte precursor cells: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.2;monocytes: 4.3" "Cell line enhanced" "Detected in many" "LHCN-M2: 222.2;U-138 MG: 279.2;U-87 MG: 244.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 240000000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" 20.3 2.8 18.7 3.8 21.5 0.6 10.0 0.0 14.3 42.5 0.0 5.0 1.5 47.2 3.3 9.5 7.6 5.0 57.1 10.5 3.3 5.0 1.8 16.1 1.4 1.5 6.5 3.1 0.6 2.4 0.5 6.0 0.6 3.5 6.2 1.5 4.9 7.2 68.6 21.1 2.3 29.9 6.3 2.1 1.7 1.8 22.9 1.8 5.8 57.7 1.9 7.1 19.4 3.2 10.2 0.0 3.6 0.5 63.2 60.6 0.1 47.1 51.9 53.6 23.1 0.1 0.4 0.1 8.5 138.5 26.0 89.1 1.0 70.7 79.8 0.0 0.2 0.1 31.4 0.1 36.4 0.0 0.4 7.9 59.9 107.8 130.4 83.9 26.7 0.0 0.2 0.5 222.2 0.5 0.1 0.2 10.6 0.0 19.4 0.0 57.7 0.0 46.2 0.4 0.1 0.1 84.4 0.3 0.1 103.5 0.8 0.1 43.1 279.2 22.7 1.6 43.0 0.2 0.1 0.2 244.0 0.2 70.1 2.2 0.5 1.4 0.0 2.1 0.0 0.5 0.0 0.0 0.5 0.5 0.0 0.0 1.1 0.0 4.3 0.3 0.0 0.2 18.7 21.5 0.0 14.3 10.5 3.3 1.5 6.5 0.6 6.3 22.9 3.2 125.4 0.0 0.5 11.1 0.3 70.7 28.7 32.3 25.0 3.0 1.0 5.8 86.9 0.0 2.6 3.7 0.0 0.1 0.9 2.1 7.9 0.4 44.5 1.0 27.1 49.2 1.8 0.0 328.8 0.0 0.2 9.7 0.0 0.7 0.0 0.0 29.6 0.3 0.6 5.0 867.0 1.6 0.0 1.9 13.3 43.3 0.3 1.4 8.8 17.8 0.0 0.4 0.0 335.8 65.0 0.1 1.4 0.0 0.0 36.7 0.0 1.3 0.8 0.4 0.0 51.0 22.7 2.9 0.6 3.3 18.8 0.1 1.2 0.7 0.1 6.4 CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 24.4;skeletal muscle: 57.0" "Cell type enriched" "Detected in some" 13 "Skeletal myocytes: 76.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 15 "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 145.8" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 17 "cerebellum: 18.7" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" 0.0 0.2 0.1 0.0 0.2 0.0 0.0 24.4 0.8 1.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 1.3 0.4 0.0 0.1 0.8 0.2 1.4 0.0 0.1 0.7 1.6 0.4 0.0 0.0 0.9 0.0 57.0 0.1 0.0 0.0 0.3 1.2 0.2 0.6 0.1 0.0 0.0 5.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.7 0.0 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 31.5 0.1 0.0 0.1 0.0 0.2 0.3 0.0 145.8 0.3 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 24.4 0.8 0.0 0.1 0.1 0.8 1.6 0.3 0.1 0.6 0.2 0.0 2.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 1.0 0.1 1.2 0.0 0.1 0.0 0.3 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.0 76.1 0.4 1.5 5.5 0.0 0.0 0.1 0.2 0.8 0.1 0.1 CDH17 "cadherin, HPT-1" ENSG00000079112 "Cadherin 17" Q12864 8 94127162-94217303 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "intestine: 314.2" "Cell type enhanced" "Detected in some" "Distal enterocytes: 569.4;Enteroendocrine cells: 108.4;Intestinal goblet cells: 183.7;Paneth cells: 408.6;Proximal enterocytes: 336.9;Undifferentiated cells: 241.6" "Group enriched" "Detected in many" 6 "colorectal cancer: 156.4;stomach cancer: 54.9" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in some" 5 "neutrophil: 16.0" "Lineage enriched" "Detected in single" 17 "granulocytes: 16.0" "Cell line enhanced" "Detected in some" "CACO-2: 98.8;OE19: 430.1;U-266/70: 157.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023614, HPA023616, CAB025143, HPA026556" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA 7500000 "Cluster 1: Neutrophils - Mixed function" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB025143: , HPA023614: AB_1845896, HPA023616: AB_1845895, HPA026556: AB_1845897" "unprognostic (2.08e-1)" "unprognostic (5.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.09e-1)" "unprognostic (3.02e-1)" "unprognostic (3.06e-2)" "unprognostic (5.60e-2)" "unprognostic (3.38e-3)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (5.47e-2)" "unprognostic (3.74e-2)" "unprognostic (2.36e-1)" "unprognostic (1.29e-1)" "unprognostic (1.31e-1)" "unprognostic (7.33e-2)" "unprognostic (1.46e-2)" 0.9 0.2 0.7 28.8 0.5 2.7 0.5 1.1 0.8 0.1 1.9 260.9 314.2 1.3 0.8 1.7 0.3 3.0 0.6 0.5 0.2 0.8 0.3 0.2 1.5 0.3 0.1 0.5 1.7 0.0 0.0 0.2 0.3 1.2 246.7 0.5 0.9 1.6 0.5 0.6 270.6 9.3 0.1 5.5 2.5 0.6 0.2 0.3 0.7 0.1 1.8 0.8 0.1 0.7 0.2 18.5 0.2 0.4 0.0 0.4 1.6 0.2 0.3 0.2 0.3 98.8 3.5 0.3 0.3 0.0 0.1 1.0 0.3 0.3 0.3 0.2 1.1 0.1 0.8 0.6 0.3 0.2 4.3 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.4 1.5 0.1 0.7 0.5 1.3 0.3 430.1 0.5 0.3 0.0 2.8 0.3 0.2 1.3 1.2 0.4 0.4 0.5 0.4 0.7 0.9 0.0 0.6 0.7 1.2 0.5 157.2 0.3 0.2 0.3 0.3 0.6 2.9 0.9 1.4 0.2 0.8 0.1 0.3 0.2 0.1 0.5 0.8 0.2 0.3 16.0 0.7 0.5 0.4 0.2 0.2 0.7 0.5 1.1 0.8 0.5 0.2 0.3 0.1 0.3 0.1 0.2 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 569.4 0.0 0.3 1.0 0.0 0.0 0.0 108.4 0.0 0.5 0.0 0.0 0.1 2.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 183.7 0.0 0.0 0.5 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 408.6 0.0 0.2 0.0 336.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 2.1 0.0 241.6 0.1 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 CDH26 VR20 ENSG00000124215 "Cadherin 26" Q8IXH8 20 59958423-60034011 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.0" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Club cells: 18.7;Oligodendrocytes: 14.9;Respiratory ciliated cells: 39.6;Syncytiotrophoblasts: 14.9" "Group enriched" "Detected in some" 6 "cervical cancer: 1.5;head and neck cancer: 0.9;lung cancer: 2.3;prostate cancer: 3.6;urothelial cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 36.4" "Low region specificity" "Detected in some" "HPA015722, HPA047578" Uncertain Supported "Plasma membrane,Microtubules" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Microtubules "HPA015722: AB_2077659, HPA047578: AB_2680091" "unprognostic (2.42e-1)" "prognostic favorable (7.62e-4)" "unprognostic (4.71e-4)" "unprognostic (8.17e-2)" "unprognostic (9.40e-2)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "prognostic favorable (3.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (3.26e-4)" "unprognostic (8.24e-3)" "unprognostic (9.96e-7)" "unprognostic (1.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" 0.9 0.4 1.0 0.3 1.5 1.0 0.8 1.2 2.0 2.0 0.3 0.7 0.4 0.6 0.4 3.4 2.0 0.4 0.7 0.9 1.8 0.5 0.3 2.1 0.4 1.6 1.7 0.3 0.5 0.3 1.7 0.4 1.5 8.0 0.3 0.4 2.0 0.5 1.0 0.6 0.8 0.4 0.6 0.8 1.2 0.7 1.9 0.9 0.6 0.3 3.0 2.7 1.3 2.6 0.0 0.7 0.2 0.0 0.6 0.2 0.4 0.2 0.0 0.1 0.0 0.8 0.8 0.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.1 7.9 0.1 0.1 0.0 0.3 0.3 0.1 1.1 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.3 0.3 0.3 0.4 0.4 0.0 0.1 0.0 0.0 0.7 0.1 36.4 0.8 0.1 0.4 0.2 0.1 0.4 0.2 0.4 0.2 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.5 1.2 2.0 0.9 1.8 1.6 1.7 1.5 0.6 1.9 2.6 4.3 6.4 6.1 17.9 0.1 0.1 1.2 6.6 0.0 0.5 1.6 0.5 0.7 0.0 18.7 0.0 0.0 1.7 0.0 0.2 0.0 0.0 3.2 2.1 0.4 2.1 0.0 2.5 9.3 0.0 0.0 0.3 0.0 0.4 1.3 0.0 0.7 0.1 0.6 0.0 8.4 0.0 6.1 1.3 0.4 1.7 0.0 1.4 0.0 7.5 0.6 0.2 1.0 7.1 14.9 0.0 0.0 0.0 0.4 10.9 0.2 0.1 39.6 0.0 0.0 0.5 2.4 0.9 0.2 0.2 0.0 14.9 0.2 0.1 0.2 7.4 CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;ovary: 32.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.8;Basal prostatic cells: 67.2;Basal respiratory cells: 161.4;Basal squamous epithelial cells: 71.7;Granulosa cells: 77.6;Melanocytes: 60.5;Pancreatic endocrine cells: 85.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 100.6;HaCaT: 263.9;HBEC3-KT: 126.9;hTCEpi: 94.3;hTERT-HME1: 72.7;RPTEC TERT1: 116.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 510000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" 3.6 0.2 1.3 3.4 1.5 0.1 8.2 1.9 1.6 9.7 47.1 0.4 0.5 10.0 8.8 26.8 12.0 1.5 0.3 3.5 0.8 6.0 0.0 2.0 2.5 1.2 1.0 32.7 0.6 1.5 4.4 4.5 0.6 13.6 0.7 0.8 12.4 4.6 0.2 25.8 0.7 4.0 1.9 10.9 1.0 1.6 1.1 18.8 1.2 0.0 11.7 3.9 11.2 1.1 100.6 0.2 0.9 0.1 0.1 0.0 8.6 0.0 0.0 0.3 0.1 61.4 36.6 0.0 0.4 0.0 0.2 263.9 2.6 126.9 0.4 0.0 1.2 0.0 0.2 0.0 0.2 0.2 0.5 0.0 94.3 0.1 72.7 0.3 0.0 0.0 0.0 0.2 0.0 48.8 0.1 0.1 5.3 0.9 8.8 0.0 0.0 0.0 116.8 44.5 0.5 0.2 0.8 0.0 50.0 45.6 29.2 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 1.6 3.5 0.8 1.2 1.0 0.6 1.9 1.1 1.1 0.2 16.0 4.6 0.7 0.0 60.8 67.2 161.4 71.7 1.2 6.8 39.2 1.4 0.0 35.9 14.7 2.1 23.4 0.5 0.5 0.0 35.7 0.5 0.9 8.2 1.3 1.2 0.0 6.0 32.1 2.1 3.7 0.0 0.9 1.3 77.6 0.0 0.0 2.8 0.0 9.1 1.5 20.3 0.0 1.9 0.2 0.6 0.7 60.5 0.0 1.0 0.4 1.0 3.0 2.2 85.7 0.1 9.4 1.2 44.5 0.0 0.1 12.6 0.5 0.0 0.6 5.9 0.4 1.0 26.5 30.7 6.3 1.2 0.1 1.5 43.1 CDH4 ENSG00000179242 "Cadherin 4" P55283 20 61252261-61940617 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;lymphoid tissue: 3.7;ovary: 6.3;skeletal muscle: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 157.0;Excitatory neurons: 54.4;Inhibitory neurons: 70.0;Oligodendrocyte precursor cells: 108.0;Skeletal myocytes: 28.7" "Group enriched" "Detected in many" 6 "glioma: 6.9;renal cancer: 3.4;thyroid cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.8;hTERT-HME1: 14.1;U-2 OS: 19.4;U-251 MG: 35.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015613 Supported "Plasma membrane" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA015613: AB_2732414" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "unprognostic (3.39e-4)" "unprognostic (2.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (6.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (6.78e-2)" 0.1 1.3 7.3 0.0 4.3 0.1 0.2 0.0 3.4 0.6 0.0 0.3 0.0 0.2 0.0 0.2 0.6 0.1 0.2 3.0 5.0 0.3 0.2 0.3 0.0 1.3 3.0 6.3 0.5 0.1 0.5 0.0 0.4 0.3 0.0 0.7 0.3 0.8 3.8 0.7 0.2 0.0 0.0 3.7 0.2 0.9 11.0 0.2 0.3 0.0 0.0 0.2 0.2 1.1 0.1 1.2 10.8 0.0 0.2 0.7 0.2 3.1 0.0 5.6 0.6 0.3 0.0 0.0 0.3 3.7 3.6 4.1 0.0 6.2 2.2 0.3 0.0 0.0 0.1 0.1 7.1 0.0 0.1 1.1 1.4 1.1 14.1 3.0 1.2 0.4 0.0 0.1 2.1 0.4 0.1 0.1 1.3 0.0 0.1 0.0 0.0 1.6 3.2 0.0 1.0 2.7 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 19.4 0.1 35.2 6.3 0.1 0.1 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.3 4.3 0.0 3.4 3.0 5.0 1.3 3.0 0.4 0.0 11.0 1.1 0.0 3.2 0.0 157.0 0.0 0.3 0.4 0.0 0.0 1.8 0.4 0.9 1.6 0.0 0.7 0.0 2.1 0.0 0.1 0.1 0.0 1.3 0.9 0.1 0.3 0.2 0.0 0.0 54.4 0.0 0.0 1.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 16.8 70.0 0.0 0.0 0.0 0.0 0.9 0.6 0.2 0.0 10.3 0.0 19.9 0.0 108.0 24.9 0.2 0.0 0.4 0.0 0.6 0.0 0.1 0.0 1.6 0.0 28.7 0.4 0.1 2.2 0.0 0.3 0.0 0.1 0.4 0.0 0.3 CDH5 "7B4, CD144" ENSG00000179776 "Cadherin 5" P33151 16 66366622-66404784 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 235.9" "Cell type enhanced" "Detected in many" "Adipocytes: 311.9;Endothelial cells: 206.1;Hepatic stellate cells: 185.6;Late spermatids: 84.6;Syncytiotrophoblasts: 80.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HUVEC TERT2: 752.5;TIME: 655.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB028366, HPA075875" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA 1300000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nuclear membrane" "CAB028366: AB_2276033, HPA075875: " "unprognostic (1.05e-1)" "unprognostic (8.13e-2)" "unprognostic (6.11e-2)" "unprognostic (4.89e-2)" "unprognostic (4.96e-2)" "unprognostic (5.50e-3)" "unprognostic (9.38e-2)" "unprognostic (5.28e-2)" "unprognostic (1.32e-1)" "unprognostic (1.46e-1)" "unprognostic (2.33e-2)" "unprognostic (2.32e-1)" "prognostic unfavorable (5.14e-4)" "unprognostic (9.49e-3)" "unprognostic (3.01e-2)" "unprognostic (2.22e-1)" "unprognostic (3.15e-2)" 84.5 13.8 16.3 14.9 15.9 0.2 71.4 15.1 16.6 16.2 11.3 16.8 7.9 19.9 8.6 12.4 17.1 29.7 84.4 13.8 14.6 19.1 24.0 95.0 13.1 16.7 16.6 8.1 7.7 10.3 7.4 235.9 17.9 11.6 10.2 1.3 12.0 9.1 41.8 16.7 17.0 27.8 15.5 20.4 13.3 10.5 22.6 5.2 37.5 58.9 7.9 22.1 14.2 15.5 0.5 0.6 4.6 0.0 0.0 0.0 47.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 119.8 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 1.0 0.0 0.3 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 752.5 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 15.7 0.0 2.4 0.0 0.1 655.1 0.0 0.9 0.1 0.0 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 16.3 15.9 15.1 16.6 13.8 14.6 16.7 16.6 17.9 15.5 22.6 15.5 311.9 0.0 6.2 1.3 0.7 4.1 0.0 0.0 1.8 0.0 1.0 2.7 17.9 5.7 0.6 1.8 0.0 6.6 0.5 0.0 0.0 0.2 33.5 0.5 0.6 206.1 0.0 10.7 0.1 0.0 48.9 7.1 0.0 1.3 3.8 0.0 185.6 1.7 2.3 0.0 0.1 0.0 0.0 35.7 6.3 84.6 6.2 1.2 12.4 28.1 0.1 0.3 0.0 0.5 0.1 0.0 0.0 2.6 2.5 0.1 0.0 0.0 0.0 0.0 0.0 5.0 5.4 10.9 0.3 0.3 3.0 80.7 1.5 3.0 0.1 0.2 CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Excitatory neurons: 67.1;Oligodendrocyte precursor cells: 60.8;Pancreatic endocrine cells: 63.8;Proximal tubular cells: 171.1;Sertoli cells: 46.0;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 477.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" 5.0 1.1 3.2 1.4 9.3 0.2 2.6 2.2 3.7 4.3 0.5 1.3 1.3 2.3 1.8 2.4 6.8 9.2 2.0 2.2 7.4 14.8 0.7 4.5 0.6 4.9 9.5 0.7 0.7 1.1 1.0 3.6 6.0 1.1 0.9 1.5 0.7 1.8 1.2 1.0 1.2 2.6 3.2 0.8 1.0 0.3 9.8 0.4 2.3 1.6 0.7 2.3 1.9 3.9 0.1 1.9 62.2 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.2 0.0 0.1 477.1 0.3 0.0 0.0 49.6 0.1 0.0 0.6 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 17.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 9.4 0.0 0.2 0.0 10.9 0.1 14.0 0.0 1.8 0.0 0.0 0.1 0.2 19.3 0.1 0.2 0.0 0.1 1.8 5.9 1.5 0.1 0.4 1.1 0.1 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 9.3 2.2 3.7 2.2 7.4 4.9 9.5 6.0 3.2 9.8 3.9 5.7 0.0 0.5 7.2 2.4 0.9 0.1 36.5 0.0 10.8 0.1 0.4 3.1 48.6 7.0 11.0 0.0 0.0 0.0 0.0 27.4 37.2 0.2 2.9 0.6 5.3 0.0 0.0 67.1 3.0 0.0 2.9 0.0 2.9 0.0 4.1 0.0 0.1 0.1 0.0 33.6 0.0 0.0 0.0 2.5 0.1 0.3 1.3 0.0 39.4 1.0 0.3 0.0 60.8 5.5 63.8 0.0 0.4 0.0 1.2 0.0 171.1 1.1 0.8 46.0 0.6 69.5 0.0 0.4 0.1 1.0 0.0 1.8 0.2 0.0 0.1 CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.4" "Group enriched" "Detected in some" 13 "Excitatory neurons: 220.8;Inhibitory neurons: 236.4;Oligodendrocytes: 145.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 7.0;fHDF/TERT166: 6.3;HaCaT: 14.4;LHCN-M2: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 870000 "Cluster 65: Brain - Ion transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014908: AB_1845908, HPA076441: " "unprognostic (1.91e-1)" "unprognostic (2.41e-1)" "unprognostic (4.02e-2)" "unprognostic (7.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.71e-2)" "unprognostic (3.66e-2)" "unprognostic (5.41e-2)" "unprognostic (2.85e-1)" "unprognostic (6.59e-2)" "unprognostic (2.91e-4)" "unprognostic (6.02e-2)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" 0.1 0.1 7.2 0.0 9.9 0.0 0.3 0.0 22.4 0.4 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.2 0.2 16.3 5.7 0.0 0.0 0.1 0.0 6.4 9.8 1.7 0.0 0.1 0.7 0.3 18.4 0.4 0.1 2.2 0.4 5.0 0.4 0.1 0.2 0.4 7.6 0.0 0.1 0.3 9.1 0.5 0.1 0.9 0.0 0.4 0.1 2.5 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 6.3 0.0 14.4 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.4 0.0 17.3 0.0 0.0 0.0 1.3 0.0 1.3 0.0 0.0 1.1 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 9.9 0.0 22.4 16.3 5.7 6.4 9.8 18.4 7.6 9.1 2.5 0.4 0.0 0.5 3.9 0.0 0.1 0.8 1.3 1.2 15.1 0.1 0.9 1.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.1 0.1 0.5 0.0 0.0 220.8 0.0 0.2 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 236.4 0.0 2.0 0.0 0.0 1.3 0.0 0.1 0.0 8.4 0.0 0.7 0.0 7.5 145.7 0.0 0.0 0.4 0.0 0.3 0.0 0.2 2.7 0.7 0.0 0.7 4.7 1.3 2.5 0.5 0.1 0.3 0.1 0.1 0.0 0.8 CDIPT "PIS, PIS1" ENSG00000103502 "CDP-diacylglycerol--inositol 3-phosphatidyltransferase" O14735 16 29858357-29863414 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056597 Enhanced Approved "Nucleoplasm,Nuclear membrane,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nuclear membrane, Plasma membrane" "HPA056597: AB_2683182" "unprognostic (7.81e-2)" "prognostic favorable (9.40e-4)" "unprognostic (1.93e-3)" "unprognostic (8.08e-3)" "unprognostic (1.50e-2)" "unprognostic (2.84e-2)" "unprognostic (7.60e-2)" "unprognostic (1.09e-2)" "unprognostic (7.03e-2)" "unprognostic (8.75e-2)" "unprognostic (5.56e-3)" "unprognostic (1.61e-1)" "unprognostic (6.17e-2)" "unprognostic (3.36e-2)" "unprognostic (6.95e-2)" "unprognostic (1.56e-1)" "unprognostic (2.48e-1)" 93.8 101.7 75.1 32.1 73.8 26.8 81.0 79.0 86.2 84.5 64.2 104.7 39.0 91.1 31.1 61.1 76.2 51.7 105.4 73.6 76.2 80.6 114.5 65.1 36.1 78.4 74.6 109.6 86.8 87.9 68.7 42.3 78.9 78.1 24.4 34.0 67.2 55.5 49.7 82.8 69.6 38.9 69.1 66.3 89.1 43.9 73.6 40.6 69.1 43.9 24.8 89.7 73.6 70.1 40.0 85.6 23.7 47.3 125.8 86.3 70.5 71.0 76.6 47.9 47.4 50.5 75.1 26.9 125.2 80.3 42.2 62.0 38.7 44.5 21.3 67.5 85.3 19.5 61.4 74.1 87.7 28.5 47.2 148.0 77.2 64.3 29.7 75.8 60.9 49.9 29.5 67.1 44.0 127.7 40.3 56.2 55.5 42.2 65.7 74.8 29.5 78.7 63.7 38.1 96.4 53.8 36.9 76.1 55.7 41.2 57.5 74.8 52.8 70.3 22.1 58.0 35.8 51.4 62.1 19.3 77.2 46.0 43.4 11.7 8.2 28.9 8.5 6.2 5.7 6.5 7.9 9.1 3.8 6.4 7.7 7.2 20.6 11.4 7.9 8.1 12.0 3.8 75.1 73.8 79.0 86.2 73.6 76.2 78.4 74.6 78.9 69.1 73.6 70.1 54.7 25.6 28.3 10.4 25.1 41.3 41.4 22.9 30.1 53.4 42.1 49.7 57.9 41.5 15.4 46.0 45.9 120.6 31.9 57.5 41.1 72.0 54.0 18.1 30.4 48.0 37.3 22.7 16.4 71.8 127.3 59.3 19.4 29.6 13.4 30.7 46.1 41.7 65.0 58.9 19.3 30.6 10.2 41.8 21.3 12.8 76.7 33.3 23.2 11.2 45.2 57.7 36.0 9.0 11.5 44.9 37.9 61.7 31.7 38.9 87.9 34.5 15.1 56.3 46.0 24.4 44.6 10.2 14.7 32.3 50.7 73.2 30.5 34.1 34.8 39.3 CDK16 "FLJ16665, PCTAIRE, PCTAIRE1, PCTGAIRE, PCTK1" ENSG00000102225 "Cyclin dependent kinase 16" Q00536 X 47217860-47229997 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 217.6" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000974, HPA001366, CAB016535" Approved Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Microtubules, Cytosol" "Plasma membrane" "CAB016535: AB_785112, HPA000974: AB_2666162, HPA001366: AB_1079584" "unprognostic (2.37e-3)" "unprognostic (6.93e-2)" "unprognostic (2.96e-2)" "unprognostic (1.16e-3)" "unprognostic (8.80e-2)" "unprognostic (2.92e-2)" "prognostic unfavorable (2.02e-6)" "unprognostic (2.85e-1)" "unprognostic (5.59e-2)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (1.09e-1)" "unprognostic (1.46e-1)" "unprognostic (1.59e-2)" "unprognostic (1.83e-1)" "unprognostic (3.89e-3)" "unprognostic (2.55e-1)" 48.2 61.3 59.0 30.4 63.6 65.7 38.6 63.8 75.0 37.9 35.7 41.4 34.2 37.5 19.7 60.7 37.6 23.8 113.3 64.3 46.5 62.7 35.0 41.6 24.3 57.2 52.4 45.3 43.1 50.6 41.7 37.9 54.9 37.2 29.6 33.6 43.9 30.4 217.6 41.9 36.3 37.7 39.6 34.0 39.1 55.2 74.3 29.9 50.3 180.4 26.5 34.2 36.8 60.6 177.6 132.5 124.8 185.0 89.5 76.2 124.2 82.4 100.7 122.3 90.5 150.2 83.3 42.1 51.2 148.1 225.7 97.7 134.3 174.7 81.8 50.9 212.6 46.0 193.8 118.8 115.7 48.7 103.0 95.5 109.6 173.8 207.4 101.7 111.0 43.7 69.6 69.7 108.4 153.1 42.7 111.1 97.9 66.3 141.8 44.9 98.8 74.4 91.7 137.7 105.0 79.4 223.2 169.9 86.5 144.4 152.0 59.3 112.9 81.1 131.4 125.4 99.8 54.6 58.2 41.8 71.4 223.0 93.1 2.6 7.8 7.5 3.7 9.3 4.9 3.4 5.0 6.0 9.7 9.8 4.3 4.6 3.2 5.5 8.4 11.3 5.5 6.1 59.0 63.6 63.8 75.0 64.3 46.5 57.2 52.4 54.9 39.6 74.3 60.6 18.8 0.0 6.1 7.2 20.2 32.5 33.0 30.6 33.6 23.5 38.2 26.8 43.3 21.5 22.1 31.3 4.2 25.7 20.1 67.2 54.8 33.7 26.5 41.2 24.5 21.8 28.1 20.6 12.5 37.0 45.2 24.0 46.4 57.7 5.7 27.8 19.2 16.7 25.3 30.3 15.8 34.3 32.6 19.5 30.8 94.8 17.1 23.5 33.8 2.8 12.6 17.1 9.2 3.5 7.8 48.4 46.1 13.2 31.9 48.3 45.1 34.7 17.9 14.6 0.0 19.1 22.6 27.6 17.5 64.2 34.7 26.0 21.5 30.0 48.6 63.3 CDK5 PSSALRE ENSG00000164885 "Cyclin dependent kinase 5" Q00535 7 151053815-151057897 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Cell cycle, Cell division, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Lissencephaly, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 65.8" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008909, HPA064535" Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB008909: , HPA064535: AB_2685280" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (4.22e-2)" "unprognostic (1.43e-1)" "unprognostic (1.10e-1)" "unprognostic (3.48e-1)" "unprognostic (5.67e-3)" "unprognostic (1.05e-2)" "unprognostic (1.22e-1)" "unprognostic (5.78e-3)" "unprognostic (6.25e-3)" "unprognostic (3.35e-1)" "unprognostic (4.47e-2)" "unprognostic (1.46e-2)" "unprognostic (1.77e-1)" "unprognostic (2.88e-1)" "unprognostic (1.11e-1)" 6.3 16.8 50.2 9.4 53.2 11.2 8.6 44.9 65.8 8.6 40.0 9.3 10.9 6.7 24.9 10.2 8.2 9.5 9.8 57.5 50.9 13.5 12.5 8.3 9.8 48.6 45.3 4.5 9.5 22.8 14.7 8.6 48.4 8.8 9.9 11.3 9.6 10.2 8.5 9.5 8.6 10.4 43.2 9.4 7.9 4.9 50.1 14.2 10.0 7.2 11.6 8.8 6.0 50.9 31.9 40.8 37.3 59.7 48.8 36.1 17.8 24.4 41.7 47.9 40.3 31.2 31.0 34.7 71.3 31.8 63.5 23.5 67.8 40.6 22.6 24.9 43.3 38.2 32.4 30.7 31.6 29.0 64.4 37.9 28.7 39.0 13.5 62.8 38.8 57.6 36.3 24.0 50.7 68.4 76.4 57.9 39.3 57.2 80.5 38.9 14.8 41.5 46.2 27.9 23.0 97.8 30.9 37.7 43.8 36.0 18.6 25.9 22.7 42.2 10.3 31.2 39.2 52.1 61.4 13.7 66.4 46.5 75.8 18.9 39.4 20.1 13.5 46.2 11.1 13.3 12.8 13.6 44.7 12.8 9.8 11.8 5.7 19.9 36.4 26.9 31.9 23.8 50.2 53.2 44.9 65.8 57.5 50.9 48.6 45.3 48.4 43.2 50.1 50.9 7.6 0.0 6.0 1.6 6.2 3.6 8.2 18.0 6.2 12.1 9.6 10.4 3.1 8.6 14.7 11.0 2.1 26.8 5.4 8.0 39.2 21.4 0.8 14.9 10.9 8.9 9.0 12.2 5.8 18.9 12.3 7.6 9.7 9.3 30.5 23.6 7.9 11.1 41.9 0.0 6.4 8.9 18.3 21.9 6.2 1.3 4.7 16.6 10.6 1.9 19.9 12.6 12.3 1.5 3.7 22.8 15.0 11.3 12.4 4.3 20.2 35.7 14.4 7.1 6.6 4.5 13.1 3.9 11.2 11.4 6.3 9.0 7.3 14.2 9.5 9.0 CDK5RAP2 "C48, CEP215, FLJ10867, MCPH3" ENSG00000136861 "CDK5 regulatory subunit associated protein 2" Q96SN8 9 120388869-120580170 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 148.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 15.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035820, HPA035821, HPA046529, CAB079753" Approved Enhanced "Cell Junctions,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Cell Junctions" "CAB079753: AB_2665827, HPA035820: AB_10671939, HPA035821: , HPA046529: AB_2679688" "unprognostic (7.72e-2)" "unprognostic (2.04e-2)" "unprognostic (2.84e-2)" "unprognostic (4.48e-2)" "unprognostic (6.63e-2)" "unprognostic (6.88e-2)" "unprognostic (6.70e-3)" "unprognostic (1.31e-1)" "unprognostic (1.71e-1)" "unprognostic (1.00e-1)" "unprognostic (7.36e-2)" "unprognostic (2.26e-2)" "unprognostic (1.88e-1)" "unprognostic (4.94e-2)" "unprognostic (2.36e-1)" "unprognostic (3.33e-2)" "unprognostic (7.41e-2)" 10.6 11.7 12.4 9.8 18.0 24.4 14.4 14.1 12.7 14.2 20.6 15.1 5.6 11.5 7.7 12.1 11.9 9.2 17.6 12.5 12.9 8.0 15.7 10.6 15.1 15.4 16.2 17.1 9.5 13.3 12.2 8.6 15.1 13.7 8.6 12.9 22.2 10.5 47.9 16.0 11.0 10.4 13.6 11.5 12.9 20.8 14.9 20.9 11.6 29.6 14.7 12.5 11.1 17.2 19.6 33.8 45.9 27.8 19.3 28.4 24.6 24.6 18.9 27.3 25.4 26.8 25.1 36.3 11.1 24.3 18.7 42.1 36.5 28.3 26.1 29.3 14.7 31.0 62.1 47.7 18.1 38.5 19.9 51.4 18.5 24.3 31.8 20.6 24.1 43.0 29.2 30.6 36.4 44.2 41.8 24.7 42.6 41.5 25.3 40.3 54.5 17.1 19.5 15.4 29.9 34.3 42.9 23.3 28.8 19.7 54.6 26.3 16.1 23.6 25.7 28.0 28.4 22.2 33.4 39.7 24.6 24.4 50.8 15.7 1.7 3.0 3.4 1.7 3.3 5.0 3.2 3.2 1.0 5.8 2.6 2.7 2.4 4.0 4.7 2.2 2.9 1.8 12.4 18.0 14.1 12.7 12.5 12.9 15.4 16.2 15.1 13.6 14.9 17.2 11.6 28.9 39.5 64.9 21.2 7.0 13.5 11.9 13.1 23.7 18.0 17.5 53.8 15.7 19.3 1.8 16.7 13.2 25.8 12.3 7.9 12.6 37.5 24.8 18.1 13.7 8.4 35.3 43.2 14.3 12.7 20.4 10.7 23.7 17.1 41.4 8.6 22.2 10.8 18.5 38.4 12.1 18.3 9.4 8.6 30.6 22.1 25.8 12.4 26.2 13.2 20.4 24.7 66.9 148.7 11.8 8.1 23.3 27.7 9.5 5.6 4.6 35.0 28.9 32.9 43.6 22.3 58.4 36.4 17.8 6.8 7.3 23.1 23.0 11.6 7.7 CDK7 "CAK, CAK1, CDKN7, MO15, STK1" ENSG00000134058 "Cyclin dependent kinase 7" P50613 5 69234795-69277430 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, DNA damage, DNA repair, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 121.0;Extravillous trophoblasts: 343.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 169.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004364, HPA007932, HPA008453, CAB079975" Enhanced Supported "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Nucleoplasm "Nucleoli fibrillar center, Plasma membrane, Cytosol" "CAB004364: AB_627243, CAB079975: , HPA007932: AB_1078492, HPA008453: " "unprognostic (3.12e-2)" "unprognostic (1.23e-1)" "unprognostic (4.87e-2)" "unprognostic (4.53e-2)" "unprognostic (3.29e-2)" "unprognostic (4.64e-2)" "unprognostic (2.49e-3)" "unprognostic (1.64e-2)" "unprognostic (7.77e-3)" "unprognostic (1.81e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (3.40e-2)" "prognostic unfavorable (9.42e-7)" "unprognostic (2.61e-1)" "unprognostic (2.38e-1)" "unprognostic (3.86e-2)" "unprognostic (1.55e-2)" 13.4 19.8 9.4 9.5 10.2 29.1 14.8 10.9 12.9 17.5 11.5 13.7 13.3 12.1 12.9 37.3 12.5 6.4 12.4 9.5 10.5 18.4 13.6 12.7 4.8 9.7 9.7 11.7 14.1 3.2 18.2 16.2 9.8 13.7 7.4 12.8 18.9 4.8 26.8 25.3 12.2 7.7 9.8 12.6 13.5 30.6 10.0 9.3 13.2 15.0 13.3 16.1 19.9 9.4 42.8 5.9 19.4 30.6 6.4 24.4 169.5 30.9 37.5 46.2 42.9 62.2 64.5 3.7 36.4 36.8 34.2 65.3 10.8 31.3 40.6 9.0 3.1 8.6 21.4 25.9 32.8 17.9 33.8 7.1 61.3 1.8 46.0 24.5 32.5 22.3 16.3 16.1 13.3 33.3 9.4 51.7 20.7 2.8 25.4 12.3 0.7 27.1 42.6 25.4 8.6 17.5 11.6 50.4 42.4 28.1 44.9 39.3 7.4 17.1 27.4 33.1 18.2 14.4 30.4 16.5 31.4 10.2 15.5 27.9 7.9 16.2 5.3 8.9 7.9 10.6 7.8 10.6 7.3 14.5 5.9 6.4 8.2 8.6 4.7 8.9 10.5 6.1 9.4 10.2 10.9 12.9 9.5 10.5 9.7 9.7 9.8 9.8 10.0 9.4 12.2 16.0 13.2 10.7 7.8 57.7 21.4 32.9 15.4 6.4 12.3 14.7 11.3 10.0 20.2 5.5 12.5 121.0 11.7 10.2 15.6 27.8 26.8 33.1 10.7 11.6 3.0 9.9 17.6 21.6 343.6 13.0 9.7 27.2 15.8 7.4 7.1 6.7 24.0 1.7 13.7 12.3 20.3 8.5 6.0 7.9 7.5 8.5 7.2 11.2 11.6 10.4 15.5 8.0 11.9 29.3 16.2 7.2 5.8 28.2 12.3 29.3 42.4 8.7 26.3 10.0 12.5 70.1 18.6 15.9 41.9 64.6 11.4 6.8 13.2 29.8 CDRT15 ENSG00000223510 "CMT1A duplicated region transcript 15" Q96T59 17 14235673-14236862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 20.9" "Group enriched" "Detected in some" 24 "Early spermatids: 117.5;Late spermatids: 88.5;Spermatocytes: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 3.8" HPA055952 Uncertain Approved "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA055952: AB_2682983" "unprognostic (3.27e-2)" "unprognostic (1.77e-2)" "unprognostic (8.61e-2)" "unprognostic (9.33e-2)" "unprognostic (5.15e-3)" "unprognostic (2.90e-1)" "unprognostic (6.16e-3)" "unprognostic (1.98e-1)" "unprognostic (1.15e-3)" "unprognostic (2.66e-1)" "unprognostic (2.55e-1)" "unprognostic (1.99e-1)" "unprognostic (5.30e-7)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (6.81e-2)" "unprognostic (2.38e-2)" 0.1 0.4 0.1 1.2 0.2 0.6 0.1 1.4 0.5 0.2 0.4 0.2 0.7 0.2 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.1 0.4 0.3 2.7 0.6 0.1 0.4 0.2 0.0 0.1 0.1 0.6 0.2 0.0 0.4 0.7 0.0 0.1 3.3 0.8 0.0 0.1 0.9 0.4 20.9 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.7 1.3 0.9 2.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 2.5 0.3 2.1 0.4 0.0 0.3 0.9 0.0 0.0 0.0 2.1 3.8 1.2 2.6 1.8 0.0 1.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 1.0 1.0 0.4 0.0 0.5 1.0 1.6 0.8 1.5 1.2 0.8 0.3 0.8 0.0 1.0 1.0 1.8 0.2 0.5 0.3 2.7 0.4 0.5 1.1 3.2 0.4 0.8 0.9 0.7 0.8 0.9 0.5 1.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.4 0.5 0.3 0.0 0.6 0.1 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.5 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CDV3 H41 ENSG00000091527 "CDV3 homolog" Q9UKY7 3 133573686-133590261 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 559.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 1103.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029761, HPA029762, HPA029763" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA029761: AB_10600193, HPA029762: AB_10611247, HPA029763: AB_10601679" "unprognostic (1.17e-2)" "unprognostic (1.22e-1)" "unprognostic (4.06e-2)" "unprognostic (4.56e-2)" "unprognostic (4.04e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.21e-6)" "unprognostic (1.20e-1)" "unprognostic (3.30e-1)" "unprognostic (8.45e-3)" "unprognostic (3.29e-3)" "unprognostic (1.13e-1)" "unprognostic (2.36e-1)" "unprognostic (7.83e-2)" "unprognostic (1.48e-2)" "unprognostic (9.87e-2)" "unprognostic (7.59e-3)" 117.0 68.6 39.1 113.7 42.0 161.3 73.0 40.6 42.9 59.3 48.3 80.0 57.5 60.6 54.9 78.7 51.6 76.4 74.5 37.0 47.1 64.4 112.9 83.6 159.3 46.0 41.8 57.9 84.3 85.8 43.0 108.5 46.0 43.2 70.8 49.2 52.7 47.7 250.9 55.0 65.5 75.7 44.6 121.6 89.0 95.9 45.8 194.5 97.4 155.9 165.6 104.3 49.3 47.8 376.2 85.5 147.6 98.0 166.7 203.6 174.5 201.6 261.1 197.6 194.7 213.4 147.0 473.9 298.0 227.4 229.2 158.2 213.5 202.0 366.4 306.1 80.1 282.3 93.2 130.9 258.2 318.7 173.4 194.7 206.7 178.2 473.4 139.6 254.5 137.9 205.7 309.9 289.5 107.1 260.9 180.9 148.9 161.6 108.2 156.8 197.6 382.2 206.9 150.7 116.5 87.8 192.0 140.4 246.0 210.0 456.3 190.8 316.4 209.4 198.5 168.5 202.7 446.9 363.2 1103.9 117.0 187.8 124.7 14.3 10.5 17.6 13.0 12.3 13.5 11.1 12.2 13.2 9.7 7.0 9.7 15.2 9.7 6.4 13.7 15.9 24.0 5.7 39.1 42.0 40.6 42.9 37.0 47.1 46.0 41.8 46.0 44.6 45.8 47.8 116.3 57.7 69.8 7.2 114.9 145.9 217.3 19.5 63.7 22.6 97.6 77.2 86.2 74.4 34.4 84.6 10.4 51.6 169.7 158.0 37.2 42.1 324.7 174.0 160.5 99.5 47.2 59.5 13.2 87.6 82.0 93.7 88.7 314.4 45.0 63.0 91.1 97.2 118.5 23.5 12.3 102.4 10.2 146.8 117.7 559.5 34.2 145.0 55.2 17.8 100.4 109.5 90.6 8.0 14.5 88.1 101.2 35.7 239.4 320.2 26.9 74.4 27.4 29.9 26.3 120.9 92.5 21.2 30.9 94.0 128.3 35.2 126.5 124.4 90.1 219.5 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 651.8" "Group enriched" "Detected in some" 9 "Distal enterocytes: 1454.0;Paneth cells: 731.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" 0.6 0.0 0.0 71.4 0.0 0.1 2.9 0.0 0.0 13.3 0.0 595.8 0.5 0.3 0.0 52.6 0.6 39.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.4 651.8 0.0 4.0 0.8 0.1 1.4 0.7 5.7 0.0 0.2 2.0 0.1 0.0 0.0 0.0 0.0 12.0 23.4 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 1454.0 0.0 116.6 0.1 0.0 0.0 0.5 8.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.0 731.2 0.0 0.0 1.4 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 38.4 30.3 CEBPE CRP1 ENSG00000092067 "CCAAT enhancer binding protein epsilon" Q15744 14 23117306-23119255 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "bone marrow: 51.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 6.6;Kupffer cells: 1.4;Macrophages: 2.3;monocytes: 2.3" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 218 "eosinophil: 750.4" "Lineage enriched" "Detected in many" 250 "granulocytes: 750.4" "Group enriched" "Detected in some" 4 "HL-60: 233.8;NB-4: 122.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002928, CAB005113" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 24: NB-4 - Immune response" "Cluster 4: Macrophages - Innate immune response" Nucleoplasm "Plasma membrane, Cytosol" "CAB005113: AB_631240, HPA002928: AB_1078494" "unprognostic (1.33e-2)" "unprognostic (4.76e-2)" "unprognostic (4.19e-2)" "unprognostic (2.04e-1)" "unprognostic (5.01e-2)" "unprognostic (1.66e-3)" "unprognostic (2.84e-1)" "unprognostic (1.49e-2)" "unprognostic (3.33e-2)" "unprognostic (5.69e-2)" "unprognostic (9.03e-2)" "unprognostic (2.22e-1)" "unprognostic (3.80e-3)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (2.57e-2)" "unprognostic (8.19e-2)" 0.1 0.0 0.1 1.6 0.1 51.8 0.0 0.0 0.2 0.0 0.0 0.2 2.4 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.5 0.4 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 3.2 0.3 0.1 3.4 0.8 0.0 0.3 0.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 233.8 39.6 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.9 122.5 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.2 0.0 26.3 0.0 0.5 3.0 750.4 0.0 0.6 0.1 0.5 1.0 0.4 1.5 0.5 1.8 1.5 3.4 0.0 0.3 1.5 0.0 1.8 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.0 0.0 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 6.6 0.0 0.0 0.0 0.0 1.4 0.6 0.1 0.0 2.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.6 0.1 0.0 0.0 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CEMIP2 TMEM2 ENSG00000135048 "Cell migration inducing hyaluronidase 2" Q9UHN6 9 71683366-71816690 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Developmental protein, Glycosidase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 92.5;placenta: 79.6" "Cell type enhanced" "Detected in some" "Adipocytes: 105.8;dendritic cells: 378.1;Glandular and luminal cells: 137.3;Plasma cells: 155.1;Syncytiotrophoblasts: 89.8;T-cells: 86.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 143.4;BEWO: 117.4;OE19: 144.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017080, HPA044889" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 21: OE19 - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Vesicles, Cytosol" "HPA017080: , HPA044889: AB_10962641" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (3.85e-2)" "unprognostic (1.01e-2)" "unprognostic (6.15e-3)" "unprognostic (1.21e-2)" "unprognostic (2.93e-2)" "unprognostic (3.53e-1)" "unprognostic (3.29e-2)" "unprognostic (1.92e-1)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.31e-4)" "unprognostic (1.13e-2)" "unprognostic (2.33e-1)" "unprognostic (7.59e-2)" "unprognostic (1.16e-1)" 25.1 5.4 9.7 24.8 6.5 29.7 11.1 9.7 8.3 5.1 15.0 24.2 27.2 7.2 2.7 6.6 5.6 41.5 7.7 19.0 2.8 10.4 60.2 35.0 23.1 4.1 3.6 2.2 19.3 92.5 4.6 79.6 4.9 7.0 28.0 17.3 11.1 8.0 4.8 6.1 23.7 11.7 4.1 15.9 33.2 6.8 8.2 18.6 9.4 8.6 20.7 32.0 3.4 5.5 22.5 85.0 143.4 6.6 13.7 22.9 117.4 81.7 48.7 51.6 40.5 24.3 31.3 0.4 20.0 18.8 11.6 35.2 38.6 9.9 73.2 2.5 11.2 38.9 20.9 68.7 23.9 0.4 9.8 28.0 11.4 38.9 8.1 14.0 68.2 3.3 4.7 10.2 28.8 15.1 4.1 0.6 28.2 144.3 8.6 3.3 39.9 2.4 31.6 60.4 6.3 0.6 19.3 12.5 20.5 45.2 8.8 1.3 30.3 33.7 38.3 17.4 39.3 1.8 37.8 0.9 6.1 3.9 43.7 0.1 1.3 3.1 1.4 1.1 0.3 0.4 1.5 1.3 0.5 3.0 2.1 1.0 2.3 0.3 1.0 0.1 2.3 0.9 9.7 6.5 9.7 8.3 19.0 2.8 4.1 3.6 4.9 4.1 8.2 5.5 105.8 0.0 0.0 0.0 47.6 0.0 0.0 0.0 0.0 0.0 58.7 46.7 0.0 0.0 0.0 14.7 0.0 47.9 378.1 0.0 0.0 20.2 0.0 42.1 24.2 14.7 0.0 0.0 0.0 36.2 14.4 4.3 0.0 137.3 0.0 3.8 0.0 0.0 46.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 30.8 0.0 0.0 155.1 0.0 0.0 11.6 0.0 0.0 0.0 0.0 10.7 0.0 0.0 0.0 0.0 89.8 86.1 3.1 0.0 0.0 CEP295 KIAA1731 ENSG00000166004 "Centrosomal protein 295" Q9C0D2 11 93661682-93730358 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038595, HPA038596, HPA038597" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA038595: AB_2676104, HPA038596: AB_10672720, HPA038597: AB_2676106" "unprognostic (1.35e-2)" "unprognostic (3.08e-1)" "unprognostic (7.66e-2)" "unprognostic (5.56e-2)" "unprognostic (5.73e-2)" "unprognostic (4.08e-3)" "unprognostic (6.03e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (3.73e-2)" "unprognostic (4.99e-4)" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (2.18e-2)" 6.6 5.8 7.5 6.3 8.1 16.0 8.3 14.4 10.5 7.6 5.0 8.7 6.2 7.0 7.4 5.8 6.8 5.2 5.3 7.3 6.9 6.2 5.0 6.0 11.1 6.3 5.9 8.3 6.6 4.7 8.4 6.3 6.6 8.3 6.8 14.7 5.5 5.2 5.3 8.9 7.5 5.5 4.9 9.4 6.2 12.0 7.6 10.3 8.7 5.8 7.4 7.7 6.6 10.2 10.5 9.4 23.9 20.4 10.8 10.4 11.6 13.2 9.7 12.2 14.2 17.3 19.2 3.1 19.1 8.3 16.9 18.7 11.8 9.5 12.4 15.0 9.4 19.0 28.2 8.6 6.5 17.1 17.4 7.7 5.6 11.6 10.0 11.5 10.4 16.9 21.6 19.4 15.8 8.8 8.9 28.1 7.5 19.6 9.7 17.7 22.6 12.6 10.1 17.9 13.9 12.9 20.9 13.8 3.7 14.8 22.8 9.4 9.6 11.3 14.8 20.9 10.1 6.9 16.7 20.2 6.7 19.7 15.9 3.3 1.7 3.6 1.5 0.9 1.2 3.2 1.3 1.0 0.8 3.5 1.6 1.4 5.2 1.6 1.3 1.7 1.1 0.4 7.5 8.1 14.4 10.5 7.3 6.9 6.3 5.9 6.6 4.9 7.6 10.2 10.9 9.6 14.3 24.2 14.0 0.0 3.3 0.0 5.2 30.5 7.0 8.9 9.4 5.7 5.6 5.5 27.1 12.8 8.6 2.5 3.9 7.8 78.7 12.4 15.0 9.6 3.6 25.7 41.2 7.8 10.3 8.8 11.2 10.2 16.4 48.8 6.8 4.2 8.0 18.5 40.8 5.5 0.0 7.9 0.0 21.4 12.8 7.7 0.0 15.0 10.3 10.3 10.3 23.6 33.5 5.3 4.1 14.3 12.2 5.6 5.8 4.0 5.1 38.1 6.6 9.4 8.7 48.8 18.6 7.5 0.0 6.6 9.8 15.8 5.8 2.8 CEP55 "C10orf3, CT111, FLJ10540" ENSG00000138180 "Centrosomal protein 55" Q53EZ4 10 93496612-93529092 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 27.4;testis: 21.7" "Cell type enhanced" "Detected in many" "Early spermatids: 29.4;Extravillous trophoblasts: 17.1;Granulosa cells: 19.8;Spermatocytes: 77.3;Spermatogonia: 17.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 8 "T-reg: 1.3" "Lineage enriched" "Detected in single" 14 "T-cells: 1.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA023430 Approved Approved "Plasma membrane,Midbody,Centriolar satellite" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centriolar satellite" Midbody "HPA023430: AB_10960212" "unprognostic (9.85e-2)" "unprognostic (1.12e-2)" "unprognostic (1.04e-1)" "unprognostic (1.29e-1)" "unprognostic (5.15e-2)" "unprognostic (4.26e-2)" "prognostic unfavorable (3.20e-9)" "prognostic unfavorable (1.45e-4)" "unprognostic (1.50e-1)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.66e-5)" "unprognostic (3.99e-2)" "prognostic unfavorable (0.00e+0)" "prognostic favorable (3.15e-4)" "unprognostic (7.86e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" 1.3 0.6 0.0 7.6 0.0 5.0 1.4 0.0 0.2 1.7 0.0 7.0 6.7 1.4 0.1 7.3 0.4 1.4 0.3 0.0 0.1 0.3 0.6 1.3 14.7 0.1 0.3 0.2 0.2 0.2 0.3 3.5 0.2 0.3 8.8 0.0 1.2 0.3 0.1 4.5 6.3 5.2 0.0 2.4 4.6 21.7 0.4 27.4 0.5 0.2 15.5 3.1 2.3 0.1 208.5 81.5 53.0 67.7 5.8 12.0 29.6 112.4 78.2 103.5 106.4 87.2 108.6 55.4 48.2 72.8 69.6 115.4 64.8 54.8 123.4 167.2 33.7 21.0 49.2 29.9 0.6 36.3 46.3 2.8 3.8 110.6 133.5 30.7 97.1 89.9 19.3 101.8 118.5 48.3 96.3 54.8 20.9 64.2 58.8 41.3 86.9 30.3 47.1 25.5 21.7 30.7 86.3 26.3 64.9 40.1 68.9 36.4 61.4 65.3 90.6 90.5 186.7 45.1 66.1 66.8 51.0 134.8 59.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.1 0.2 0.0 1.3 0.0 2.7 3.6 0.9 1.9 0.0 0.0 1.8 2.0 0.4 2.8 0.2 0.0 0.0 7.7 0.9 3.3 0.0 0.6 29.4 1.7 2.0 1.5 0.0 2.5 0.5 0.2 17.1 2.3 8.2 3.6 0.0 19.8 2.2 0.3 12.9 0.0 0.3 4.5 4.1 7.0 5.1 8.2 0.3 5.1 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.3 0.0 0.4 14.8 1.1 0.4 0.0 0.2 0.0 0.0 0.5 4.5 77.3 17.3 16.1 1.3 1.5 4.3 1.6 7.9 1.7 CEP57L1 "bA487F23.2, C6orf182, MGC21731" ENSG00000183137 "Centrosomal protein 57 like 1" Q8IYX8 6 109095110-109174418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 50.3;Spermatocytes: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040378 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040378: AB_10794028" "unprognostic (5.93e-3)" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-2)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (4.69e-3)" "unprognostic (3.63e-2)" "unprognostic (7.25e-2)" "unprognostic (1.27e-1)" "unprognostic (2.33e-1)" "unprognostic (9.97e-2)" "unprognostic (2.42e-5)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (8.48e-2)" "unprognostic (1.72e-1)" 10.5 7.6 5.1 7.8 5.9 10.2 10.2 10.8 7.8 8.2 4.6 8.5 8.7 9.3 10.5 6.2 6.0 9.4 7.7 5.8 4.1 8.0 10.0 6.6 8.9 4.9 4.2 6.5 7.5 16.9 5.6 10.1 5.5 6.4 10.9 12.0 5.2 6.3 6.1 6.8 7.8 10.8 3.9 7.7 7.3 26.2 5.5 14.4 8.7 6.6 7.4 6.4 6.5 7.9 17.9 7.9 23.1 22.9 21.2 35.2 18.1 40.3 22.1 35.8 39.8 11.9 15.3 16.0 18.4 20.9 30.8 9.1 16.1 15.4 56.1 20.3 16.1 34.8 18.9 12.3 19.6 28.5 14.5 21.2 11.0 30.3 29.9 19.2 32.4 52.5 63.9 52.5 32.4 11.8 32.0 24.6 7.6 14.7 14.6 25.7 17.4 15.7 17.0 7.4 17.4 14.4 19.8 14.7 12.9 15.0 18.2 43.9 14.7 23.1 13.6 24.4 42.9 15.4 19.1 25.3 21.8 43.1 18.9 15.9 5.2 6.6 4.7 6.1 5.1 3.3 4.8 6.7 5.7 6.3 4.5 6.7 3.6 11.6 9.6 6.0 6.9 4.6 5.1 5.9 10.8 7.8 5.8 4.1 4.9 4.2 5.5 3.9 5.5 7.9 12.9 6.4 5.3 12.4 6.3 3.3 7.6 7.4 7.4 6.6 6.8 7.2 10.3 2.8 6.8 5.5 20.9 9.8 9.7 4.2 7.9 7.0 50.3 12.8 18.5 10.6 5.4 18.1 31.9 5.4 13.2 15.5 8.2 6.9 5.1 20.5 8.2 6.3 10.2 5.0 31.1 3.1 8.2 4.1 6.8 39.3 17.4 7.7 8.8 27.2 7.7 10.4 8.2 26.2 36.1 6.0 4.5 12.4 13.2 4.4 5.7 13.4 9.8 12.3 13.1 21.8 14.1 75.7 13.0 5.8 4.4 8.5 6.7 13.6 6.1 5.0 CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039382, HPA040056" Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039382: AB_2676479, HPA040056: AB_10671048" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" 6.0 6.0 6.3 5.3 6.7 4.7 6.4 7.7 6.4 9.1 7.7 8.9 4.0 9.8 6.7 6.3 8.9 5.1 6.2 6.6 6.9 8.6 3.3 5.7 6.0 5.8 5.6 10.1 6.1 7.0 9.3 5.3 4.7 12.5 4.4 7.4 6.7 5.9 5.9 6.6 6.7 6.9 4.0 6.4 6.2 4.2 7.3 6.2 7.5 4.3 4.3 8.0 6.8 6.0 19.1 25.7 17.1 14.7 9.1 11.0 9.9 14.7 9.8 25.5 19.4 9.3 11.2 7.6 7.8 15.1 14.4 10.5 16.9 11.9 17.6 20.2 10.4 5.9 18.5 8.9 7.2 8.3 5.7 13.3 16.2 24.1 16.2 10.4 19.5 10.4 9.2 11.0 12.3 14.2 9.4 6.4 7.3 10.4 8.0 10.4 9.2 6.6 11.9 10.3 24.1 17.7 15.1 10.3 8.8 10.3 7.7 6.7 12.6 18.4 16.1 16.0 15.3 5.3 9.1 7.0 15.8 7.8 14.0 12.8 3.1 1.6 2.7 4.6 4.9 3.3 2.9 2.4 1.8 5.7 2.8 3.3 3.7 2.1 2.4 3.7 3.4 1.7 6.3 6.7 7.7 6.4 6.6 6.9 5.8 5.6 4.7 4.0 7.3 6.0 12.7 28.9 16.0 17.3 9.5 5.1 11.5 14.5 8.0 16.3 11.7 11.8 17.5 10.0 19.0 20.2 18.8 9.3 9.6 8.0 11.7 19.1 15.1 49.2 24.9 14.8 9.7 13.3 17.2 16.6 11.2 17.7 10.7 17.3 17.1 21.1 14.6 5.6 11.8 20.2 13.6 9.7 8.2 5.3 5.1 8.5 16.1 8.9 5.4 14.0 9.8 9.6 10.3 9.5 15.9 15.1 5.2 12.8 5.4 6.7 9.9 16.3 48.3 38.6 0.0 17.5 16.1 20.3 13.8 7.5 4.5 4.2 9.0 12.7 8.6 6.6 CERCAM "CEECAM1, GLT25D3" ENSG00000167123 "Cerebral endothelial cell adhesion molecule" Q5T4B2 9 128411751-128437351 "Metabolic proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 551.5" "Cell type enriched" "Detected in many" 7 "Oligodendrocytes: 626.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 280.5;ASC TERT1: 284.1;fHDF/TERT166: 271.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021657, HPA051595" Uncertain Approved "Nucleoplasm,Nucleoli,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA021657: AB_1846507, HPA051595: AB_2681545" "unprognostic (2.87e-2)" "unprognostic (1.37e-3)" "unprognostic (1.89e-3)" "unprognostic (2.19e-1)" "unprognostic (4.68e-3)" "unprognostic (7.79e-3)" "unprognostic (3.29e-3)" "unprognostic (5.68e-2)" "unprognostic (1.00e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (1.59e-1)" "unprognostic (5.93e-2)" "prognostic unfavorable (3.33e-16)" "unprognostic (1.34e-2)" "unprognostic (1.04e-1)" "unprognostic (6.05e-3)" "prognostic unfavorable (3.30e-5)" 26.1 8.9 249.9 12.3 411.3 2.5 24.5 248.6 378.3 42.4 140.1 20.9 7.9 35.0 9.7 13.1 23.4 31.2 34.0 261.5 322.7 25.9 3.7 16.9 4.1 344.1 349.4 31.2 30.1 31.0 106.4 49.4 323.9 27.9 7.7 1.0 21.4 22.8 7.0 15.0 12.3 47.4 224.7 10.9 15.8 11.1 386.4 2.4 23.4 7.0 3.9 29.9 30.8 551.5 44.7 26.0 35.2 38.2 280.5 284.1 27.4 145.5 149.7 41.2 32.0 10.3 2.4 0.0 58.3 271.9 33.5 33.8 14.7 22.2 13.9 11.7 25.6 2.9 24.1 15.5 89.7 5.4 84.4 171.6 11.7 48.4 10.5 157.7 44.3 3.0 13.0 36.5 51.8 82.3 2.3 55.7 1.8 2.3 25.4 4.7 23.6 7.3 18.4 15.5 4.9 8.5 33.8 43.1 16.7 10.1 34.4 13.7 48.2 103.5 27.3 138.1 23.2 42.2 35.0 0.8 99.7 17.1 21.0 0.1 0.6 0.0 1.8 0.7 0.1 0.1 0.1 2.1 0.7 0.0 0.0 2.3 0.0 0.6 0.0 1.0 0.0 1.3 249.9 411.3 248.6 378.3 261.5 322.7 344.1 349.4 323.9 224.7 386.4 551.5 8.5 6.4 10.3 7.2 3.5 8.9 6.5 7.0 10.8 1.7 8.7 6.9 3.9 0.0 13.6 11.0 0.0 18.4 5.8 0.0 0.0 11.6 2.7 3.1 18.7 7.7 0.0 2.5 2.9 3.4 61.1 82.3 3.6 6.7 8.8 9.8 16.8 0.1 6.2 6.7 3.3 0.0 2.0 0.8 10.4 2.3 24.2 2.9 40.9 3.7 1.3 0.1 17.5 11.6 626.9 4.5 0.0 26.4 17.9 5.0 0.0 0.9 3.9 0.9 6.6 27.8 26.4 8.6 22.2 2.4 4.1 19.6 3.3 5.9 0.0 2.8 CFAP157 C9orf117 ENSG00000160401 "Cilia and flagella associated protein 157" Q5JU67 9 127706988-127716002 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.6;choroid plexus: 35.9;fallopian tube: 59.5" "Group enriched" "Detected in some" 4 "Early spermatids: 56.8;Endometrial ciliated cells: 153.5;Late spermatids: 85.0;Respiratory ciliated cells: 189.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 7.3;HeLa: 6.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA021474, HPA021786" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA021474: AB_1845801, HPA021786: AB_1845802" "unprognostic (1.69e-1)" "unprognostic (2.80e-2)" "unprognostic (2.41e-2)" "prognostic favorable (1.45e-4)" "unprognostic (3.02e-1)" "unprognostic (1.58e-1)" "unprognostic (4.71e-3)" "unprognostic (1.49e-1)" "unprognostic (3.14e-4)" "unprognostic (7.72e-2)" "unprognostic (4.93e-4)" "unprognostic (9.32e-3)" "unprognostic (4.95e-3)" "unprognostic (5.71e-4)" "unprognostic (4.34e-2)" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" 0.2 0.3 2.4 0.1 1.4 0.1 0.2 0.8 0.4 9.1 35.9 0.1 0.0 1.1 1.8 0.8 59.5 0.6 0.3 3.2 3.3 0.5 0.1 11.2 0.4 12.6 18.6 0.4 1.1 0.2 4.7 0.2 7.2 0.3 0.0 0.1 0.5 0.2 0.3 0.6 0.1 0.1 7.5 0.3 0.2 10.1 2.6 0.1 0.4 0.0 0.0 0.4 0.1 1.9 1.4 7.3 0.9 1.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.8 0.8 1.4 1.0 0.0 1.6 3.6 0.0 0.0 0.0 2.8 1.2 0.8 6.2 1.7 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.5 0.0 2.1 2.9 0.4 0.0 5.0 1.1 0.4 0.7 1.5 3.6 2.0 1.1 1.2 0.0 0.3 5.1 1.0 1.7 2.9 0.4 0.1 2.4 0.4 1.5 1.6 1.4 4.1 0.8 0.7 2.3 0.9 0.7 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.4 0.8 0.4 3.2 3.3 12.6 18.6 7.2 7.5 2.6 1.9 0.2 9.6 10.5 0.0 0.0 0.0 0.3 0.0 0.0 0.7 1.3 0.6 0.0 0.0 27.9 0.0 0.0 0.1 0.1 0.2 1.9 0.3 56.8 153.5 1.9 0.8 0.0 0.0 0.0 0.0 0.1 1.0 0.0 4.8 2.5 0.1 0.4 0.2 0.2 0.0 0.0 0.6 0.0 0.6 0.0 85.0 0.3 0.5 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.1 0.7 0.1 0.4 0.5 0.4 189.5 0.4 0.0 0.4 0.3 14.3 0.9 0.0 0.0 0.0 0.3 1.4 0.3 0.2 CFAP206 "C6orf165, dJ382I10.1, FLJ25974" ENSG00000272514 "Cilia and flagella associated protein 206" Q8IYR0 6 87407972-87464465 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "fallopian tube: 22.3;testis: 59.1" "Group enriched" "Detected in some" 4 "Early spermatids: 300.7;Spermatocytes: 128.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 2.3;RPTEC TERT1: 2.6;T-47d: 4.5" "HPA044891, HPA072261" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Cell Junctions" "HPA044891: AB_10960832, HPA072261: AB_2686501" "unprognostic (4.31e-1)" "unprognostic (8.75e-3)" "unprognostic (2.40e-1)" "unprognostic (2.31e-1)" "unprognostic (5.51e-2)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (4.68e-3)" "unprognostic (3.13e-2)" "unprognostic (3.99e-3)" "unprognostic (9.08e-3)" "unprognostic (4.22e-2)" "unprognostic (1.46e-1)" "unprognostic (8.54e-2)" "unprognostic (2.26e-2)" 0.1 0.4 1.0 0.0 0.9 0.0 0.3 0.5 0.9 0.7 4.3 0.0 0.0 0.5 0.6 0.0 22.3 0.1 0.2 0.8 1.4 0.9 0.1 1.5 0.0 2.3 2.6 0.1 0.1 0.7 1.2 0.1 1.6 0.5 0.0 0.5 0.1 0.3 0.0 0.1 0.0 0.1 1.5 0.0 0.0 59.1 1.7 0.0 1.4 0.1 0.0 0.2 0.0 0.9 0.0 0.5 0.2 1.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.1 0.5 0.0 0.0 0.0 1.0 0.4 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.6 0.6 0.5 0.3 0.2 0.2 0.1 0.0 4.5 0.1 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.5 0.9 0.8 1.4 2.3 2.6 1.6 1.5 1.7 0.9 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.3 0.3 0.0 0.0 7.4 0.0 0.0 0.1 0.0 0.0 1.9 0.3 300.7 15.8 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 32.5 2.1 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 1.2 0.0 0.1 0.0 1.4 43.7 0.4 0.0 0.0 0.1 128.8 4.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFAP299 C4orf22 ENSG00000197826 "Cilia and flagella associated protein 299" Q6V702 4 80335730-80963750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 19.8;testis: 27.4" "Cell type enriched" "Detected in some" 54 "Endometrial ciliated cells: 54.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;BJ: 1.6;hTERT-RPE1: 2.5;LHCN-M2: 1.0;SCLC-21H: 1.1;U-251 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043383 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA043383: AB_10797140" "unprognostic (4.77e-4)" "unprognostic (1.52e-1)" "unprognostic (4.06e-2)" "unprognostic (1.45e-2)" "unprognostic (7.24e-2)" "unprognostic (3.27e-1)" "unprognostic (6.93e-2)" "unprognostic (5.90e-2)" "unprognostic (2.67e-3)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.79e-2)" "unprognostic (4.61e-2)" 0.1 0.0 0.9 0.0 1.0 0.0 0.1 1.4 0.5 0.7 2.6 0.1 0.1 0.2 0.0 0.0 19.8 0.1 0.0 1.0 1.0 0.3 0.0 1.4 0.1 5.3 3.7 0.1 0.0 0.0 0.1 0.0 2.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 27.4 1.2 0.1 0.6 0.0 0.0 0.0 0.0 1.1 1.4 0.0 0.0 0.0 0.1 0.7 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.0 1.4 0.5 1.0 1.0 5.3 3.7 2.3 3.5 1.2 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 54.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CFAP58 "bA554P13.1, C10orf80, CCDC147, FLJ35908" ENSG00000120051 "Cilia and flagella associated protein 58" Q5T655 10 104353833-104455102 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 8.4;testis: 13.4" "Group enriched" "Detected in some" 4 "Early spermatids: 73.3;Endometrial ciliated cells: 25.1;Late spermatids: 58.9;Respiratory ciliated cells: 56.9;Spermatocytes: 34.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 2.1" "Lineage enriched" "Detected in single" 21 "granulocytes: 2.1" "Cell line enhanced" "Detected in some" "BJ hTERT+: 3.1;U-2 OS: 6.5" "Not detected" "Not detected" "Region enhanced" "Detected in single" "midbrain: 1.9" "HPA036555, HPA071938" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 9: U-2 OS - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Plasma membrane, Cytosol" "HPA036555: AB_10673622, HPA071938: " "unprognostic (5.32e-1)" "unprognostic (2.59e-1)" "unprognostic (6.26e-2)" "unprognostic (1.57e-3)" "unprognostic (5.41e-3)" "unprognostic (1.01e-1)" "unprognostic (9.62e-2)" "unprognostic (5.64e-2)" "unprognostic (3.11e-1)" "unprognostic (2.18e-1)" "unprognostic (8.93e-2)" "unprognostic (3.15e-1)" "unprognostic (1.65e-1)" "unprognostic (3.97e-2)" "unprognostic (6.81e-2)" "unprognostic (4.19e-2)" "unprognostic (1.59e-1)" 0.4 0.6 1.0 0.5 1.3 0.4 0.4 0.4 0.7 2.2 2.4 0.5 0.1 1.8 0.2 0.2 8.4 0.2 2.5 0.8 1.2 0.7 0.1 1.3 0.3 2.9 3.7 0.5 0.3 0.7 1.5 0.4 2.2 0.5 0.0 0.6 0.2 0.4 1.3 0.3 0.2 0.6 2.0 0.3 0.3 13.4 1.0 0.1 0.8 0.8 0.4 0.3 0.6 1.1 0.1 0.0 0.7 0.1 0.1 0.3 0.1 1.0 3.1 0.6 1.6 0.0 0.0 2.4 0.2 0.4 1.7 0.2 0.0 0.2 1.8 0.3 0.1 0.5 0.9 0.0 0.3 0.3 0.4 0.3 1.3 0.5 1.6 1.3 1.0 0.1 0.7 0.7 0.8 0.0 0.0 0.7 0.2 0.0 0.0 0.2 0.2 0.3 0.3 0.0 0.4 0.2 0.0 0.1 0.5 0.7 0.1 0.4 2.0 0.6 6.5 0.3 1.8 0.2 0.0 0.1 0.7 0.8 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 1.0 1.3 0.4 0.7 0.8 1.2 2.9 3.7 2.2 2.0 1.0 1.1 0.4 0.0 0.5 1.6 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 10.0 0.0 9.3 0.0 0.0 0.1 0.1 0.0 0.0 0.6 73.3 25.1 0.3 0.4 0.0 0.0 4.0 0.2 0.4 0.7 0.0 0.4 0.0 0.3 1.8 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 58.9 0.6 0.2 0.0 1.9 0.1 0.7 1.0 1.0 0.0 0.3 0.0 1.2 0.0 0.2 0.0 0.0 56.9 0.3 0.0 0.8 1.0 34.4 4.0 0.0 0.0 0.1 0.0 0.6 0.0 0.2 CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;choroid plexus: 13.5;fallopian tube: 25.7;testis: 9.4" "Group enriched" "Detected in many" 4 "Early spermatids: 204.5;Late spermatids: 164.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.8" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" 0.0 0.1 2.3 0.0 2.1 0.0 0.1 1.0 1.0 1.3 13.5 0.1 0.0 0.5 1.8 0.0 25.7 0.4 0.0 2.6 2.8 0.4 0.0 2.7 0.0 8.4 12.1 0.0 0.3 0.1 3.5 0.0 6.2 0.1 0.2 9.2 0.1 0.1 0.0 0.0 0.4 0.0 6.1 0.0 0.3 9.4 2.4 0.0 0.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.0 1.0 2.6 2.8 8.4 12.1 6.2 6.1 2.4 3.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.8 7.7 8.8 0.0 4.3 6.8 0.0 12.5 0.0 0.1 1.1 0.0 0.6 204.5 45.1 0.5 0.2 29.1 0.0 0.0 1.5 0.0 0.2 2.0 1.8 0.0 0.2 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.0 0.0 164.3 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.8 0.7 0.0 1.1 1.9 1.1 29.2 19.5 0.0 0.1 0.0 14.4 5.7 0.0 0.0 0.0 0.2 0.1 5.1 0.1 CFB "BF, BFD, H2-Bf" ENSG00000243649 "Complement factor B" P00751 6 31945650-31952084 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Complement alternate pathway, Immunity, Innate immunity" "Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "liver: 2613.2" "Cell type enhanced" "Detected in many" "Ductal cells: 873.6;Exocrine glandular cells: 197.3;Hepatocytes: 284.0;Pancreatic endocrine cells: 318.0;Proximal enterocytes: 139.7" "Cancer enhanced" "Detected in all" "liver cancer: 78.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 15.0;ASC TERT1: 23.0;EFO-21: 25.1;fHDF/TERT166: 14.1;HSkMC: 19.1;U-87 MG: 10.1" "Low region specificity" "Detected in all" "HPA000951, HPA001817, HPA001832, CAB016381" Supported Approved "Endoplasmic reticulum,Vesicles,Cell Junctions" "Secreted to blood" NA NA 879000000 120000000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 62: Liver - Hemostasis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Endoplasmic reticulum, Vesicles" "Cell Junctions" "CAB016381: AB_627562, HPA000951: AB_2797216, HPA001817: AB_1078779, HPA001832: AB_1078778" "prognostic favorable (2.76e-5)" "unprognostic (1.02e-1)" "unprognostic (1.44e-1)" "unprognostic (7.94e-2)" "unprognostic (1.82e-2)" "unprognostic (8.56e-2)" "unprognostic (8.08e-3)" "unprognostic (8.81e-2)" "unprognostic (3.51e-1)" "unprognostic (2.26e-2)" "unprognostic (1.32e-2)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.53e-5)" "unprognostic (1.36e-1)" "unprognostic (5.13e-2)" "unprognostic (1.05e-2)" "unprognostic (3.68e-2)" 143.7 18.0 3.6 32.8 3.6 0.1 28.5 3.4 9.9 16.3 3.9 22.3 28.1 8.2 14.2 24.1 53.7 0.8 42.6 3.7 3.4 58.7 2613.2 39.2 4.2 4.1 3.7 9.9 51.8 0.2 17.7 5.0 3.8 60.3 14.5 1.4 43.3 0.0 3.0 7.7 73.1 48.3 3.4 12.9 54.5 2.1 3.7 1.9 15.5 0.7 6.7 17.8 9.2 3.6 0.5 1.9 0.1 0.0 15.0 23.0 0.1 0.0 0.2 1.1 0.0 0.1 8.6 0.1 25.1 14.1 0.6 6.0 0.0 1.8 1.2 1.0 0.3 0.7 0.4 0.5 0.0 1.0 0.4 19.1 0.4 0.6 0.5 1.3 0.2 0.1 0.3 0.7 0.1 0.2 0.1 0.3 0.4 0.0 0.4 0.3 0.3 1.3 1.7 0.5 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.2 0.0 3.4 1.2 0.4 0.4 0.7 2.1 1.0 10.1 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 3.6 3.6 3.4 9.9 3.7 3.4 4.1 3.7 3.8 3.4 3.7 3.6 1.0 0.0 16.9 0.0 2.6 0.8 0.9 64.8 11.4 0.3 4.9 0.9 0.4 44.3 127.3 5.5 0.0 0.1 0.0 3.7 3.9 873.6 0.0 1.9 0.4 3.9 2.4 16.0 0.2 197.3 0.2 34.6 20.9 1.2 0.0 0.0 11.7 284.0 1.0 0.0 0.2 8.5 18.3 19.7 1.0 0.0 2.8 1.1 0.0 5.6 18.1 0.4 0.0 0.0 0.0 318.0 10.6 0.0 0.1 8.6 139.7 17.1 75.4 0.7 0.0 1.0 12.6 0.1 0.1 3.9 1.8 1.6 1.6 0.0 12.4 4.5 CFL2 NEM7 ENSG00000165410 "Cofilin 2" Q9Y281 14 34709113-34714823 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 372.8;skeletal muscle: 719.9;tongue: 686.4" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 522.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037078, HPA045599" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 47000000 "Cluster 37: B-cells - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB037078: AB_259128, HPA045599: AB_2679383" "unprognostic (1.05e-1)" "unprognostic (1.28e-1)" "unprognostic (1.29e-2)" "unprognostic (1.59e-1)" "unprognostic (3.02e-2)" "unprognostic (2.80e-3)" "unprognostic (3.82e-1)" "unprognostic (2.02e-1)" "unprognostic (3.02e-1)" "unprognostic (2.92e-2)" "unprognostic (2.48e-2)" "unprognostic (1.27e-1)" "unprognostic (1.65e-2)" "unprognostic (3.13e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-2)" "prognostic unfavorable (2.16e-5)" 48.7 52.5 71.7 28.6 98.7 18.1 24.6 90.3 116.1 39.8 53.9 92.5 14.3 73.4 19.5 69.0 42.6 24.1 372.8 69.4 85.0 31.4 125.9 24.9 10.7 85.7 83.6 41.2 9.4 24.4 10.9 35.3 88.7 75.4 28.1 41.0 17.1 107.3 719.9 8.2 24.0 115.0 74.7 12.7 36.1 21.7 81.2 10.4 29.4 686.4 9.9 56.8 24.3 130.5 87.1 77.7 49.5 32.0 51.1 185.6 27.9 146.6 170.5 145.6 151.4 61.9 38.5 30.6 58.5 245.2 104.9 17.1 107.4 32.5 268.6 4.2 45.0 6.6 87.4 144.5 81.6 8.2 5.3 139.3 12.4 122.2 67.7 96.8 145.9 4.5 9.9 26.8 186.9 25.5 6.3 4.3 16.3 15.4 118.9 5.4 158.1 4.7 55.1 17.7 10.3 41.7 96.6 21.5 51.2 36.2 47.8 7.5 124.6 140.9 93.0 66.1 72.9 34.3 22.8 11.7 51.7 11.4 34.5 1.8 1.0 1.3 1.9 1.0 3.1 4.9 2.2 2.1 1.6 3.0 1.7 1.8 0.3 1.8 0.4 1.6 2.1 0.9 71.7 98.7 90.3 116.1 69.4 85.0 85.7 83.6 88.7 74.7 81.2 130.5 39.6 105.8 41.6 6.2 17.0 20.0 88.6 31.3 23.9 62.8 19.6 16.6 522.2 22.8 26.3 22.0 20.9 32.2 11.5 0.9 60.7 45.2 2.6 40.3 60.5 45.1 9.5 11.4 9.6 39.7 60.5 69.9 6.1 56.2 5.7 25.8 47.2 112.0 15.6 77.4 14.2 2.4 57.0 15.7 14.4 10.1 57.2 10.6 30.2 11.2 5.7 112.9 15.5 8.0 93.8 24.7 4.0 98.6 60.4 84.0 1.0 101.9 24.7 57.8 32.9 83.9 115.8 49.3 51.9 16.1 19.5 21.3 21.1 47.9 4.6 58.5 CFLAR "c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT" ENSG00000003402 "CASP8 and FADD like apoptosis regulator" O15519 2 201116154-201176687 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Apoptosis, Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 609.9;Urothelial cells: 521.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 4 "neutrophil: 392.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 392.6" "Cell line enhanced" "Detected in all" "U-266/70: 214.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019044, CAB022157, CAB025216" Uncertain Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "Nuclear bodies" "CAB022157: , CAB025216: , HPA019044: AB_10696204" "unprognostic (4.61e-2)" "unprognostic (5.32e-2)" "unprognostic (2.49e-1)" "unprognostic (1.44e-1)" "unprognostic (2.95e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.46e-2)" "unprognostic (9.01e-2)" "unprognostic (1.76e-1)" "unprognostic (6.12e-2)" "unprognostic (3.08e-2)" "unprognostic (4.91e-2)" "unprognostic (2.90e-2)" "unprognostic (7.83e-2)" "unprognostic (9.13e-2)" "unprognostic (6.84e-2)" "unprognostic (2.24e-2)" 122.4 50.6 38.8 103.9 40.9 247.6 83.1 54.1 47.4 57.0 75.6 86.0 59.2 57.9 60.6 68.0 66.6 71.6 184.8 39.4 32.7 57.5 59.2 174.6 91.1 46.5 40.5 38.3 40.7 31.8 29.4 94.0 42.1 65.6 56.4 12.4 58.0 63.2 222.8 51.0 64.8 58.8 36.6 98.1 56.5 25.3 51.9 54.1 78.8 89.2 107.3 78.7 61.7 46.1 21.5 42.9 30.0 17.9 92.3 71.0 37.5 53.6 92.1 34.3 41.6 50.4 78.4 5.8 49.6 62.5 41.6 15.5 9.8 40.3 53.9 160.7 29.9 32.3 38.4 82.2 63.6 24.2 102.2 76.8 39.6 58.2 50.3 41.7 176.7 7.3 110.8 131.2 63.1 17.9 11.3 96.3 10.2 17.2 32.7 11.7 7.2 46.5 42.5 44.0 6.6 11.8 35.7 31.2 43.2 19.6 22.1 44.8 193.6 71.0 29.5 26.7 26.1 214.6 76.2 35.9 50.6 19.5 36.3 91.8 60.3 70.3 54.4 61.8 48.4 25.6 46.5 52.1 33.4 20.9 29.5 38.3 392.6 45.2 68.5 23.0 60.7 42.0 38.8 40.9 54.1 47.4 39.4 32.7 46.5 40.5 42.1 36.6 51.9 46.1 191.3 451.9 234.9 30.3 126.4 54.8 229.6 164.9 29.0 10.9 38.9 30.0 205.8 102.9 206.7 69.9 31.3 77.2 166.2 132.5 74.3 148.8 83.3 202.8 75.0 261.0 95.1 59.1 6.9 72.5 34.8 89.5 73.4 219.2 81.6 93.4 201.0 97.5 68.6 13.5 16.8 76.8 40.7 123.2 609.9 44.8 51.9 278.0 97.8 146.1 247.0 23.4 276.0 29.7 56.8 166.4 155.6 49.7 317.8 386.0 116.7 101.5 276.1 30.7 39.5 113.2 77.9 14.4 12.2 33.2 86.1 70.1 168.3 56.1 50.9 521.3 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CGNL1 "FLJ14957, JACOP, KIAA1749, PCING" ENSG00000128849 "Cingulin like 1" Q0VF96 15 57375967-57550717 "Disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 87.2;Astrocytes: 79.7;Hepatic stellate cells: 58.5;Hepatocytes: 65.5;Microglial cells: 156.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 52.7;SuSa: 37.6;TIME: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013500, HPA056911, HPA069214" Enhanced Supported "Nuclear bodies,Cell Junctions" No No "Cluster 15: Liver - Metabolism" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "Nuclear bodies" "CAB013500: , HPA056911: AB_2683274, HPA069214: AB_2686102" "unprognostic (1.04e-2)" "unprognostic (2.42e-1)" "unprognostic (1.52e-2)" "prognostic favorable (3.55e-4)" "unprognostic (3.22e-1)" "unprognostic (1.51e-3)" "prognostic favorable (5.58e-4)" "unprognostic (4.32e-2)" "unprognostic (2.34e-1)" "unprognostic (4.86e-2)" "unprognostic (4.05e-2)" "unprognostic (1.91e-2)" "prognostic favorable (1.37e-6)" "unprognostic (2.26e-2)" "unprognostic (3.39e-1)" "unprognostic (1.88e-3)" "unprognostic (1.18e-2)" 5.0 11.5 23.6 1.5 23.0 0.0 19.8 19.8 18.5 32.0 47.2 3.2 1.2 17.8 4.4 11.0 8.9 2.8 20.1 18.6 24.2 68.3 36.0 21.0 1.1 28.9 28.2 5.8 18.6 9.6 4.1 28.8 27.7 28.7 2.3 12.3 32.3 16.2 0.7 11.5 2.5 10.8 20.0 0.4 15.5 6.6 29.9 4.6 19.8 1.9 3.2 8.9 20.2 15.7 0.0 1.3 13.1 0.0 0.0 0.0 0.2 0.2 2.9 1.1 2.4 8.4 0.1 0.0 11.4 1.7 1.9 0.0 6.2 0.1 1.8 0.1 1.0 0.1 0.1 5.7 0.2 0.1 0.0 0.4 0.4 1.3 0.0 4.4 52.7 0.5 0.0 0.0 2.1 2.4 0.0 0.2 6.5 3.7 0.6 0.1 6.6 0.3 4.4 0.0 0.3 0.7 0.0 5.1 0.0 37.6 0.5 0.6 32.5 0.0 3.3 0.1 1.9 0.0 0.0 0.0 0.2 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.6 23.0 19.8 18.5 18.6 24.2 28.9 28.2 27.7 20.0 29.9 15.7 3.9 51.3 87.2 79.7 0.2 4.6 13.4 5.1 4.6 0.4 27.4 27.1 21.0 10.0 11.7 22.0 0.0 1.0 1.6 0.9 41.1 9.9 3.0 11.0 9.4 21.8 13.1 2.7 0.7 13.2 1.0 17.1 11.2 11.8 1.3 3.5 58.5 65.5 0.3 0.0 1.9 3.7 18.3 1.6 4.9 18.1 19.9 0.9 7.2 156.4 0.6 43.7 0.0 11.1 1.5 4.3 1.2 27.8 0.0 18.6 0.2 39.4 2.2 1.4 0.0 6.6 2.3 0.6 0.6 0.8 2.4 1.4 1.2 0.6 2.2 7.0 CHCHD7 "COX23, MGC2217" ENSG00000170791 "Coiled-coil-helix-coiled-coil-helix domain containing 7" Q9BUK0 8 56211686-56218809 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050783 Approved Approved "Cell Junctions,Aggresome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Cell Junctions" Aggresome "HPA050783: AB_2681236" "unprognostic (1.64e-2)" "unprognostic (3.23e-2)" "unprognostic (3.18e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (4.46e-2)" "unprognostic (2.43e-1)" "unprognostic (5.04e-2)" "unprognostic (8.38e-3)" "unprognostic (1.62e-1)" "unprognostic (9.03e-2)" "unprognostic (2.24e-1)" "unprognostic (1.15e-1)" "prognostic favorable (9.47e-5)" "unprognostic (1.94e-1)" "unprognostic (5.07e-1)" "unprognostic (1.77e-2)" "unprognostic (2.50e-1)" 24.9 20.2 25.8 30.0 27.1 29.2 25.8 30.8 32.5 22.9 25.2 30.7 33.2 18.6 46.0 22.8 24.5 17.1 41.6 26.6 26.6 42.2 26.2 28.0 39.4 27.0 26.3 49.1 26.9 36.0 38.1 19.3 27.3 26.4 30.2 32.6 35.3 21.0 37.5 21.3 36.0 18.5 28.6 46.3 27.7 11.7 26.7 36.5 28.0 39.7 38.1 28.1 24.2 28.7 59.3 18.9 39.4 13.1 100.9 71.3 42.4 41.0 37.0 30.7 23.0 46.2 68.9 54.7 34.8 23.6 43.6 32.3 40.7 61.3 38.6 24.5 77.4 83.6 45.5 66.2 51.8 72.1 52.0 86.2 54.2 22.2 98.0 43.8 32.8 100.0 41.8 34.9 74.1 29.0 72.2 106.5 35.1 93.5 25.6 82.0 12.0 46.3 57.3 63.3 10.2 7.0 21.8 32.2 31.2 47.8 34.1 40.5 49.0 16.5 35.4 53.7 39.5 37.1 40.3 93.5 46.0 105.3 28.9 55.2 37.8 53.3 42.4 38.2 40.2 60.4 46.9 43.5 44.1 52.5 55.0 49.6 15.2 49.7 35.0 62.6 60.1 33.9 25.8 27.1 30.8 32.5 26.6 26.6 27.0 26.3 27.3 28.6 26.7 28.7 31.7 19.2 77.9 2.6 72.5 20.8 44.1 49.0 16.5 31.4 37.1 27.1 93.7 35.8 48.0 49.7 14.6 44.0 66.0 75.4 125.2 41.4 27.5 25.2 15.9 29.8 39.6 32.6 9.1 75.4 80.8 26.3 92.8 32.2 53.8 13.8 42.8 78.4 162.3 13.5 8.0 66.3 34.6 67.8 45.3 13.4 37.0 58.0 53.4 14.0 68.5 50.8 60.8 1.5 6.5 65.4 63.9 30.9 59.3 45.3 115.0 82.3 41.5 37.9 13.1 23.9 39.0 51.4 39.4 34.7 23.9 42.1 61.7 21.7 73.5 48.8 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CHMP2A "BC-2, CHMP2, VPS2, VPS2A" ENSG00000130724 "Charged multivesicular body protein 2A" O43633 19 58551566-58555105 "Predicted intracellular proteins" "Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041153, HPA042031" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 230000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA041153: AB_10964358, HPA042031: AB_10961727" "unprognostic (1.80e-1)" "unprognostic (4.70e-2)" "unprognostic (7.29e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (2.54e-1)" "unprognostic (3.86e-2)" "unprognostic (2.60e-1)" "unprognostic (1.01e-1)" "unprognostic (1.45e-2)" "unprognostic (2.69e-1)" "unprognostic (1.45e-1)" "unprognostic (2.98e-1)" "unprognostic (2.21e-1)" "unprognostic (3.09e-2)" "unprognostic (4.23e-2)" "unprognostic (2.71e-2)" 131.8 185.9 144.9 86.8 149.6 162.3 125.1 153.7 171.9 108.9 143.5 141.3 113.4 111.7 150.1 154.9 104.6 83.1 182.6 144.4 147.8 163.3 161.3 116.9 81.9 151.1 147.0 101.9 125.0 147.8 118.7 95.8 151.3 112.5 124.1 75.2 137.2 97.1 222.9 158.4 121.9 83.6 149.0 121.2 143.8 73.9 146.8 82.6 123.2 151.7 95.1 114.3 113.7 157.4 110.4 290.9 91.4 85.0 138.9 172.9 112.9 100.0 204.3 52.0 56.0 86.3 160.1 29.3 143.2 168.1 149.2 87.7 76.1 190.4 43.7 98.8 628.2 71.8 214.0 134.7 266.6 121.1 108.0 201.5 266.0 81.5 257.8 175.3 153.1 135.5 86.8 135.6 159.5 187.1 153.7 111.3 38.3 304.2 220.3 65.2 78.6 222.0 230.1 246.8 107.3 181.2 162.0 213.7 123.4 57.3 164.3 121.5 174.4 262.0 37.7 77.2 117.3 339.0 404.9 95.2 185.0 141.0 176.6 278.9 247.4 351.1 134.9 232.7 114.5 127.0 148.0 153.1 216.2 123.0 102.0 116.3 820.6 131.6 243.9 197.1 215.5 208.4 144.9 149.6 153.7 171.9 144.4 147.8 151.1 147.0 151.3 149.0 146.8 157.4 166.1 99.3 119.8 9.4 72.9 165.6 261.4 287.7 69.4 73.9 124.7 120.6 118.7 154.4 207.2 165.5 16.7 288.8 76.5 555.2 442.2 332.6 121.9 194.0 109.2 143.6 155.4 142.5 5.3 522.5 296.8 113.5 115.7 198.8 121.5 102.1 142.5 214.0 269.1 52.2 5.6 296.6 217.7 142.0 145.8 90.9 145.1 134.5 215.3 6.5 203.6 217.6 147.2 3.0 13.4 479.8 615.3 133.2 77.3 258.5 607.0 599.8 242.1 94.3 85.5 103.9 169.7 116.8 89.7 109.5 198.5 460.0 89.2 149.3 226.3 372.7 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CHRNA2 ENSG00000120903 "Cholinergic receptor nicotinic alpha 2 subunit" Q15822 8 27459756-27479883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 14 "brain: 72.1;prostate: 29.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.5;Inhibitory neurons: 14.8;Prostatic glandular cells: 2.4;Theca cells: 3.4" "Cancer enriched" "Detected in single" 421 "prostate cancer: 30.2" "Region enhanced" "Detected in many" "thalamus: 72.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA048348 Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge" "HPA048348: " "unprognostic (1.10e-2)" "unprognostic (1.47e-1)" "unprognostic (2.23e-2)" "unprognostic (3.19e-1)" "unprognostic (6.19e-2)" "unprognostic (6.29e-3)" "unprognostic (1.19e-2)" "unprognostic (2.13e-1)" "unprognostic (1.91e-1)" "unprognostic (7.60e-2)" "unprognostic (1.70e-1)" "unprognostic (1.47e-1)" 0.0 0.5 15.8 0.2 5.5 0.9 1.4 38.1 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 8.0 0.0 0.0 0.2 0.1 15.7 21.5 0.0 0.2 0.0 0.3 0.0 3.5 29.0 0.0 3.7 0.0 0.0 0.1 0.2 0.2 0.0 2.3 0.1 0.0 0.0 72.1 2.9 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 15.8 5.5 38.1 2.9 0.7 8.0 15.7 21.5 3.5 2.3 72.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 39.3;lymphoid tissue: 65.8;retina: 53.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 164.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 356.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" 0.3 39.3 4.4 5.1 2.0 0.0 0.1 6.3 1.0 1.0 0.3 8.1 1.5 0.5 0.0 0.1 0.0 0.3 0.4 0.7 2.3 0.0 0.0 0.2 0.3 3.1 6.4 0.1 0.2 0.0 1.1 0.1 10.0 0.2 4.0 53.5 0.1 0.0 0.1 0.7 3.0 3.7 0.3 0.1 2.8 1.0 9.2 65.8 0.2 0.0 0.8 0.2 0.7 1.0 0.1 0.3 0.7 0.6 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 1.5 0.0 8.8 0.0 0.0 0.3 1.4 0.5 0.4 0.1 0.0 0.1 4.0 0.0 0.3 0.0 0.0 0.0 0.0 22.6 0.2 0.0 0.0 0.3 7.1 0.0 1.6 0.1 0.2 0.4 0.3 0.1 0.0 0.4 67.7 356.1 0.3 0.1 0.1 0.5 0.4 0.0 0.0 0.1 1.7 0.1 0.4 0.2 0.7 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.0 6.3 1.0 0.7 2.3 3.1 6.4 10.0 0.3 9.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 164.7 0.0 0.0 0.2 1.9 0.0 3.7 0.1 1.2 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.7 0.4 3.6 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.1 0.1 0.3 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.1 CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 13.0;Extravillous trophoblasts: 11.5;Intestinal goblet cells: 9.8;Spermatocytes: 12.4;Spermatogonia: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" 0.8 2.0 1.9 1.9 1.8 0.5 1.5 2.7 3.0 1.0 2.0 4.0 4.8 1.3 1.1 1.6 0.5 4.4 1.3 1.7 1.8 0.3 0.3 0.5 0.7 1.7 2.2 0.7 1.9 0.3 0.2 1.1 2.4 1.9 4.2 2.5 0.7 0.4 3.9 0.6 2.4 2.1 1.6 0.3 2.8 3.1 2.4 0.7 0.3 0.5 1.1 1.8 1.1 2.7 16.5 41.8 22.4 12.5 2.7 1.9 9.1 12.0 5.8 13.0 23.4 16.1 76.7 9.8 28.6 2.6 34.7 14.3 43.5 17.6 13.2 20.1 51.9 18.3 29.5 16.2 1.4 12.4 24.7 0.7 3.1 3.5 4.7 4.8 24.5 13.6 18.2 12.5 8.3 36.1 15.9 4.3 18.2 32.4 11.5 20.1 25.8 9.9 15.7 39.2 37.7 55.0 28.6 27.5 14.1 12.7 61.2 3.2 5.3 17.6 21.0 13.0 38.0 14.3 63.4 11.3 10.6 19.8 16.5 1.0 0.4 0.7 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.3 0.7 0.3 0.4 0.2 0.0 0.1 1.9 1.8 2.7 3.0 1.7 1.8 1.7 2.2 2.4 1.6 2.4 2.7 0.9 0.0 0.0 0.3 1.4 3.2 13.0 0.5 8.6 7.6 1.2 2.9 1.2 2.8 0.2 0.0 0.0 2.6 0.4 1.2 0.0 0.3 1.2 0.5 0.6 2.0 3.5 0.8 1.0 2.0 11.5 1.0 0.5 0.6 0.0 1.5 0.0 0.3 1.0 5.0 1.1 9.8 0.0 0.0 2.3 2.6 0.3 0.8 1.8 0.0 0.2 0.4 1.0 0.5 0.9 0.7 0.1 0.4 0.9 6.7 0.1 0.4 0.1 0.7 0.0 1.3 1.6 12.4 28.8 2.9 1.6 1.0 2.0 0.2 2.1 3.2 CHRNB4 ENSG00000117971 "Cholinergic receptor nicotinic beta 4 subunit" P30926 15 78624111-78727754 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 3.0;retina: 2.7;testis: 5.8" "Group enriched" "Detected in some" 11 "Early spermatids: 44.1;Late spermatids: 54.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "SCLC-21H: 30.9;SH-SY5Y: 40.7" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.3;pons and medulla: 1.4;thalamus: 4.2" HPA059484 Approved "Endoplasmic reticulum,Cell Junctions" NA NA "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Endoplasmic reticulum" "Cell Junctions" "HPA059484: " "unprognostic (4.74e-2)" "unprognostic (4.54e-1)" "unprognostic (1.26e-2)" "unprognostic (8.77e-5)" "unprognostic (8.15e-2)" "unprognostic (6.43e-3)" "unprognostic (1.10e-1)" "unprognostic (2.30e-2)" "unprognostic (1.09e-1)" "unprognostic (3.19e-1)" "unprognostic (1.40e-1)" "unprognostic (1.49e-1)" "unprognostic (1.45e-4)" "unprognostic (7.00e-3)" "unprognostic (2.58e-1)" "unprognostic (8.50e-2)" "unprognostic (7.76e-2)" 0.0 2.4 0.2 0.6 0.1 0.3 0.0 0.1 0.2 0.2 0.2 1.1 0.0 0.3 0.3 0.6 0.0 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.5 0.7 1.8 0.1 0.0 0.2 0.4 0.0 1.4 0.0 0.4 2.7 0.1 0.0 0.3 0.1 0.3 0.4 0.0 0.4 0.3 5.8 0.2 3.0 0.1 0.0 0.4 0.0 0.2 0.3 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.6 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 30.9 40.7 0.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.5 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.2 0.5 0.7 1.8 1.4 0.0 0.2 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 2.1 0.1 0.0 0.0 0.0 0.0 44.1 0.3 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 54.9 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.5 0.1 0.2 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.1 0.0 0.0 0.0 1.6 2.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 CHRND ACHRD ENSG00000135902 "Cholinergic receptor nicotinic delta subunit" Q07001 2 232525993-232536667 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skeletal muscle: 57.6" "Group enriched" "Detected in some" 10 "Muller glia cells: 4.0;Skeletal myocytes: 4.4" "Cancer enriched" "Detected in single" 7 "head and neck cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 49 "RH-30: 99.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA056404, HPA065404" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA056404: AB_2732603, HPA065404: AB_2732734" "unprognostic (1.69e-2)" "unprognostic (7.93e-2)" "unprognostic (3.28e-3)" "unprognostic (7.75e-3)" "unprognostic (6.04e-2)" "unprognostic (1.10e-1)" "unprognostic (7.25e-2)" "unprognostic (1.90e-1)" "unprognostic (4.97e-8)" "unprognostic (7.52e-2)" "unprognostic (2.86e-1)" "unprognostic (2.46e-1)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 6.3 0.7 0.0 57.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 6.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 99.4 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.1 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CIAO3 "FLJ21988, HPRN, IOP1, NAR1, NARFL, PRN" ENSG00000103245 "Cytosolic iron-sulfur assembly component 3" Q9H6Q4 16 729760-741329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 11.6;Cytotrophoblasts: 20.6;Extravillous trophoblasts: 10.9;Hofbauer cells: 16.0;Syncytiotrophoblasts: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 142.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040851 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA040851: AB_10794427" "unprognostic (6.31e-2)" "prognostic favorable (1.32e-5)" "unprognostic (7.61e-2)" "unprognostic (8.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.27e-3)" "unprognostic (8.85e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (8.39e-2)" "unprognostic (4.45e-3)" "unprognostic (3.02e-1)" "prognostic favorable (9.83e-5)" "unprognostic (2.49e-2)" "unprognostic (8.15e-2)" "unprognostic (2.62e-1)" "unprognostic (8.33e-3)" 10.4 13.8 16.8 7.5 18.0 10.7 12.3 17.2 27.2 11.6 14.1 16.1 13.3 12.1 11.5 18.5 12.2 6.7 23.1 17.6 16.0 19.5 22.4 9.4 11.7 17.6 17.1 10.1 15.7 12.1 14.9 5.8 17.8 18.9 4.9 4.5 16.8 9.2 20.5 18.1 16.5 4.8 16.3 17.3 16.1 11.3 16.6 12.0 13.0 13.2 7.9 13.1 13.7 17.5 9.1 26.1 10.1 14.9 10.3 7.3 24.6 12.7 9.4 17.2 15.0 18.8 22.0 12.9 19.2 8.0 12.7 20.3 10.0 15.4 6.1 24.1 22.8 10.9 14.7 15.5 13.2 19.3 15.0 9.2 19.1 10.2 8.5 11.4 12.9 50.7 20.3 12.0 8.5 33.9 17.5 9.0 8.6 18.4 16.5 142.5 15.3 23.7 10.6 9.0 11.8 16.1 15.3 36.0 13.4 6.0 33.0 19.7 14.0 14.5 13.6 16.1 11.5 15.8 12.1 35.7 9.9 11.0 19.0 2.7 11.1 8.9 10.9 9.9 8.3 14.8 11.0 8.9 11.9 9.2 8.6 12.4 2.3 15.5 11.6 9.4 11.7 9.9 16.8 18.0 17.2 27.2 17.6 16.0 17.6 17.1 17.8 16.3 16.6 17.5 3.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 20.6 3.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 10.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 14.2 0.5 0.0 0.0 0.0 CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1385.8;Respiratory ciliated cells: 1103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "CAB012991: AB_2533205, HPA042413: AB_2732498, HPA048825: AB_2680533" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (7.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.77e-1)" "unprognostic (4.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (1.85e-1)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" 65.6 163.6 65.4 79.7 69.2 205.5 67.4 67.8 76.5 93.8 96.7 147.9 130.1 44.6 88.1 127.3 146.6 77.4 101.9 62.7 68.8 220.1 195.7 86.7 97.0 70.1 70.3 43.9 214.1 98.3 93.0 38.0 68.7 127.6 138.1 29.1 116.6 72.7 58.8 40.4 128.5 45.3 69.3 117.0 99.3 113.8 69.2 64.4 89.1 42.3 120.9 93.7 68.3 69.3 119.5 261.4 23.8 83.7 98.7 102.7 38.9 123.8 107.2 99.6 87.2 104.7 207.4 34.7 129.7 144.0 125.7 124.2 48.0 141.8 54.0 81.9 114.2 77.5 182.3 175.9 96.2 155.2 71.4 72.2 84.9 91.9 64.6 113.7 129.1 83.7 105.8 53.5 76.4 233.3 118.4 179.4 36.7 223.9 134.0 66.1 62.8 139.7 256.1 199.4 18.7 22.8 168.7 136.5 135.7 41.5 105.3 93.3 81.7 109.6 77.0 132.0 153.2 73.0 122.0 40.3 176.1 174.9 47.8 168.9 201.8 271.3 226.9 248.9 188.0 476.4 269.9 249.4 224.4 418.0 221.5 218.0 118.2 205.7 230.0 149.7 245.8 399.6 65.4 69.2 67.8 76.5 62.7 68.8 70.1 70.3 68.7 69.3 69.2 69.3 77.4 89.8 104.2 14.7 203.7 85.7 253.6 520.1 84.8 12.0 152.0 118.5 86.9 128.7 469.1 183.9 10.4 106.7 198.7 670.9 453.9 372.1 380.8 480.8 101.3 83.9 97.1 62.3 7.7 662.9 117.6 96.5 149.9 222.8 138.8 66.9 79.6 230.1 209.0 3.3 6.6 379.5 463.9 102.5 148.0 1385.8 105.3 180.5 128.1 4.7 187.5 138.4 184.4 5.0 12.2 620.2 794.2 92.6 88.8 699.6 661.4 668.6 1103.6 25.5 39.5 62.3 140.4 160.3 69.0 218.1 67.3 66.1 227.5 91.8 315.5 577.8 CIB3 KIP3 ENSG00000141977 "Calcium and integrin binding family member 3" Q96Q77 19 16161368-16173525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.2" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 30.2;Late spermatids: 9.5" "Cancer enriched" "Detected in single" 7 "breast cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 2.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.3" "Cell line enhanced" "Detected in some" "HMC-1: 4.5;MCF7: 2.2;NB-4: 1.4;THP-1: 1.3;U-937: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043553, HPA043995" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "HPA043553: AB_10964566, HPA043995: " "unprognostic (8.43e-2)" "unprognostic (7.26e-5)" "unprognostic (3.18e-2)" "unprognostic (2.62e-1)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (2.93e-2)" "unprognostic (3.05e-1)" "unprognostic (5.68e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-2)" 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 1.4 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.7 0.0 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.3 30.2 0.0 0.1 0.0 0.0 0.2 0.1 1.8 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CKAP5 "ch-TOG, KIAA0097, TOG, TOGp" ENSG00000175216 "Cytoskeleton associated protein 5" Q14008 11 46743048-46846308 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 119.7;Spermatocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039377, HPA040375" Supported Approved "Nucleoli,Nucleoli rim,Plasma membrane,Centrosome" NA Yes 360000 "Cluster 27: Non-specific - Gene expression" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Centrosome" "Nucleoli, Nucleoli rim" "HPA039377: AB_10805477, HPA040375: AB_10794739" "unprognostic (8.00e-2)" "unprognostic (7.35e-2)" "unprognostic (2.35e-1)" "unprognostic (4.12e-2)" "unprognostic (1.91e-1)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (6.09e-2)" "unprognostic (1.12e-2)" "unprognostic (2.21e-2)" "unprognostic (4.30e-3)" "unprognostic (3.77e-2)" "unprognostic (2.03e-1)" "unprognostic (2.71e-1)" "unprognostic (1.12e-1)" "unprognostic (3.48e-1)" "unprognostic (4.69e-2)" 12.8 30.7 15.9 15.1 19.5 25.9 14.9 30.8 24.3 11.7 5.2 18.5 12.6 15.7 12.2 13.0 11.5 12.2 21.3 21.4 18.0 11.5 45.5 10.4 18.4 21.0 17.4 27.8 9.0 21.2 12.5 17.3 22.9 15.9 17.2 57.0 9.1 13.2 37.8 13.7 12.3 19.3 17.5 11.9 16.1 33.0 20.2 36.4 9.6 28.8 18.5 13.5 10.8 24.6 104.7 95.8 212.6 90.8 48.7 73.0 48.3 117.1 69.4 107.8 114.6 76.8 33.3 104.5 41.0 76.0 117.0 116.2 144.0 62.7 134.3 102.0 107.6 176.6 80.2 78.4 35.0 139.6 76.7 37.0 34.0 60.3 125.6 56.1 79.3 97.9 129.5 103.8 89.2 71.2 127.9 39.2 114.7 78.8 73.0 131.2 210.0 98.3 34.7 63.3 96.8 83.9 149.8 56.9 57.3 88.9 103.9 39.1 64.0 106.2 92.9 180.8 176.2 59.2 137.3 158.6 66.5 64.9 105.9 4.6 4.2 4.6 6.1 6.2 5.9 6.5 4.5 6.9 6.1 6.2 5.4 5.8 0.7 8.6 6.2 3.9 5.6 3.1 15.9 19.5 30.8 24.3 21.4 18.0 21.0 17.4 22.9 17.5 20.2 24.6 13.4 25.6 23.6 32.3 17.4 8.5 11.0 17.9 16.5 19.3 11.6 12.3 65.2 12.8 18.8 9.2 37.5 19.4 11.2 13.3 9.8 12.2 119.7 19.7 21.0 16.5 12.1 32.6 61.9 7.8 15.0 27.8 29.0 18.8 37.9 55.5 11.7 8.1 18.7 13.5 63.1 16.9 16.2 17.6 5.6 50.7 19.6 19.6 7.2 30.9 16.5 16.2 16.5 32.6 51.7 13.7 15.2 29.0 26.4 14.2 9.1 9.3 30.7 25.6 19.7 18.0 21.4 107.4 59.3 24.3 11.6 11.5 16.1 83.3 19.8 9.7 CLCA2 CLCRG2 ENSG00000137975 "Chloride channel accessory 2" Q9UQC9 1 86424171-86456553 "Predicted membrane proteins" "Cell adhesion, Ion transport, Transport" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "esophagus: 117.5;skin 1: 88.7;vagina: 53.1" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 47.4;Basal respiratory cells: 57.5;Basal squamous epithelial cells: 39.9;Club cells: 37.1;Early spermatids: 30.2;Squamous epithelial cells: 167.1;Suprabasal keratinocytes: 54.8;Urothelial cells: 52.9" "Cancer enhanced" "Detected in many" "head and neck cancer: 146.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "hTCEpi: 210.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047192 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 96000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA047192: AB_2679977" "unprognostic (1.04e-2)" "unprognostic (1.58e-1)" "unprognostic (3.96e-3)" "unprognostic (6.99e-2)" "unprognostic (6.33e-2)" "unprognostic (1.40e-1)" "unprognostic (6.15e-2)" "unprognostic (1.09e-1)" "unprognostic (1.26e-1)" "unprognostic (2.73e-1)" "unprognostic (9.99e-3)" "unprognostic (1.97e-8)" "unprognostic (3.88e-1)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "unprognostic (2.72e-1)" 0.8 0.1 0.2 0.1 0.6 0.0 4.6 0.4 0.5 22.8 0.1 0.6 0.2 0.0 0.5 117.5 0.2 0.1 0.0 0.2 0.3 0.0 0.0 0.3 0.0 0.4 0.3 0.0 0.0 0.0 0.1 0.7 0.4 2.4 0.7 0.0 13.2 0.2 0.2 88.7 0.8 0.0 0.4 0.0 0.1 0.6 0.3 1.0 0.0 0.0 26.0 21.2 53.1 1.0 0.0 0.0 0.0 0.0 0.6 3.0 38.9 1.7 2.7 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.1 9.7 0.0 33.8 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 210.8 1.0 10.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.9 0.7 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.4 0.5 0.2 0.3 0.4 0.3 0.4 0.4 0.3 1.0 0.0 0.0 0.0 0.7 0.0 47.4 13.1 57.5 39.9 0.0 7.7 2.8 0.4 0.0 37.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 30.2 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.3 4.1 0.0 3.1 4.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 2.5 2.1 0.3 0.0 8.0 0.0 0.0 0.0 0.6 0.2 0.0 167.1 54.8 0.1 0.5 0.0 0.1 52.9 CLCA4 CaCC2 ENSG00000016602 "Chloride channel accessory 4" Q14CN2 1 86547078-86580754 "Predicted membrane proteins, Transporters" Transport "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 373.9;intestine: 257.8" "Group enriched" "Detected in many" 6 "Distal enterocytes: 597.0;Paneth cells: 183.2;Squamous epithelial cells: 158.7;Urothelial cells: 176.9" "Cancer enhanced" "Detected in many" "cervical cancer: 21.4;urothelial cancer: 15.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 1368 "RT4: 430.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA017045, HPA064770" Uncertain Approved "Nucleoplasm,Plasma membrane,Aggresome" "Intracellular and membrane" NA NA 150000 "Cluster 37: Intestine - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Aggresome" "HPA017045: AB_2291679, HPA064770: " "unprognostic (1.38e-4)" "unprognostic (1.52e-1)" "prognostic favorable (7.47e-4)" "unprognostic (2.73e-2)" "unprognostic (7.03e-2)" "prognostic favorable (8.63e-4)" "unprognostic (7.59e-2)" "unprognostic (3.35e-1)" "unprognostic (1.26e-1)" "unprognostic (6.01e-2)" "unprognostic (1.20e-1)" "unprognostic (2.57e-2)" "unprognostic (2.29e-1)" "unprognostic (5.69e-2)" "unprognostic (3.43e-2)" 0.6 0.0 6.3 13.9 9.4 0.0 2.2 6.7 8.0 44.6 3.2 257.8 0.1 0.1 0.1 373.9 0.2 0.2 0.1 6.2 6.6 0.1 0.1 0.0 0.0 10.9 7.0 0.0 0.1 0.0 0.5 0.0 8.7 2.5 143.5 0.0 23.1 0.2 0.1 17.1 29.1 2.9 7.1 0.1 0.6 0.3 8.0 0.1 0.0 0.0 30.1 99.3 66.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 430.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.4 6.7 8.0 6.2 6.6 10.9 7.0 8.7 7.1 8.0 12.7 0.1 0.0 0.0 0.0 2.9 3.3 40.3 6.5 2.8 0.0 1.9 1.8 0.4 0.0 17.5 1.8 0.0 0.0 0.2 597.0 0.0 0.0 0.4 7.3 0.1 0.3 8.3 0.0 0.1 0.0 0.0 0.4 0.0 3.5 8.9 0.0 0.0 0.0 0.0 0.0 0.1 9.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 27.1 0.0 183.2 0.0 1.2 9.7 4.7 0.0 1.9 0.0 0.0 0.0 0.4 0.1 0.0 158.7 11.9 0.0 1.5 0.0 12.0 176.9 CLCN5 "ClC-5, CLC5, DENTS, hCIC-K2, hClC-K2, NPHL1, NPHL2, XLRH, XRN" ENSG00000171365 "Chloride voltage-gated channel 5" P51795 X 49922596-50099235 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "epididymis: 23.7;kidney: 46.2;liver: 16.9" "Cell type enriched" "Detected in many" 4 "Skeletal myocytes: 214.4" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.6;plasmacytoid DC: 2.8" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in all" 4 "CACO-2: 49.0;RH-30: 66.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000401, HPA003213" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" Cytosol "HPA000401: AB_1078531, HPA003213: AB_2666843" "unprognostic (3.33e-2)" "unprognostic (6.15e-2)" "unprognostic (3.13e-1)" "unprognostic (1.57e-1)" "unprognostic (7.59e-2)" "unprognostic (1.27e-1)" "unprognostic (1.54e-1)" "unprognostic (8.08e-3)" "unprognostic (1.60e-1)" "unprognostic (5.21e-2)" "prognostic favorable (5.20e-4)" "unprognostic (3.59e-2)" "prognostic favorable (2.05e-8)" "unprognostic (7.87e-3)" "unprognostic (1.07e-1)" "unprognostic (1.25e-1)" "unprognostic (3.60e-2)" 2.1 2.5 1.7 1.7 1.9 1.5 1.6 3.8 1.6 1.8 2.5 2.4 4.9 4.0 23.7 2.4 3.0 3.9 1.3 1.5 2.9 46.2 16.9 2.8 1.3 3.2 3.2 7.0 2.1 1.4 2.3 5.8 3.7 1.7 2.8 3.4 2.5 1.0 4.0 4.8 3.8 2.9 2.5 1.8 2.9 2.1 2.7 1.1 2.2 2.8 1.2 1.4 2.0 2.3 2.9 5.4 4.2 5.5 12.8 7.5 7.9 2.8 1.2 1.6 1.9 49.0 3.0 3.5 1.2 2.5 9.7 2.8 9.9 1.7 2.2 1.1 7.5 3.3 2.7 12.8 7.2 4.1 5.7 4.9 1.6 3.7 5.9 1.2 5.8 4.0 4.3 4.7 5.3 3.2 1.6 1.4 5.7 7.4 2.4 1.9 66.0 5.2 6.0 5.5 7.2 5.2 3.3 3.0 5.1 14.1 3.0 2.1 3.8 1.6 3.7 12.7 1.4 3.6 11.9 7.3 2.8 6.6 8.5 0.0 0.9 0.0 0.1 0.9 0.1 0.1 0.2 0.2 2.6 0.1 0.0 0.0 0.2 0.1 0.1 2.8 0.0 0.3 1.7 1.9 3.8 1.6 1.5 2.9 3.2 3.2 3.7 2.5 2.7 2.3 4.3 9.6 8.4 20.5 2.1 7.1 1.8 1.6 5.2 27.4 1.8 1.4 1.9 2.8 2.3 12.9 2.1 6.2 17.7 11.3 11.7 4.1 2.0 8.0 10.0 5.5 0.0 3.4 11.5 3.5 2.6 7.9 8.6 22.8 2.5 0.8 1.4 35.2 11.1 8.4 15.6 6.6 4.1 17.6 19.8 0.6 5.3 10.9 3.6 46.9 10.1 2.7 2.1 20.6 9.6 7.7 7.3 13.2 2.2 4.0 20.4 38.8 4.2 4.3 0.0 214.4 4.8 0.9 2.3 8.1 9.5 5.1 1.9 9.3 7.0 4.8 CLCN6 "CLC-6, KIAA0046" ENSG00000011021 "Chloride voltage-gated channel 6" P51797 1 11806096-11848079 "Plasma proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032097 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA032097: AB_10670827" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-1)" "unprognostic (8.83e-2)" "unprognostic (2.08e-1)" "unprognostic (3.84e-3)" "unprognostic (1.51e-3)" "unprognostic (6.49e-2)" "unprognostic (7.76e-2)" "unprognostic (6.61e-3)" "unprognostic (1.71e-3)" "unprognostic (3.44e-1)" "unprognostic (2.13e-2)" "unprognostic (6.91e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" 13.6 14.8 19.1 7.5 19.1 7.7 11.9 17.3 21.3 14.8 8.2 13.7 6.3 12.6 8.7 7.4 12.6 4.9 13.2 18.0 23.5 11.8 13.7 13.8 7.4 29.6 29.5 18.6 9.2 6.0 20.2 6.4 32.1 12.5 4.8 15.2 7.8 5.5 11.6 9.8 13.0 7.3 15.4 12.0 10.5 17.1 22.5 5.3 14.4 8.1 6.1 11.5 11.1 19.4 5.1 6.4 13.9 11.1 15.2 15.4 3.8 4.1 11.1 7.1 11.7 8.6 15.9 7.9 4.4 5.5 19.3 8.8 9.0 8.8 6.7 3.6 4.5 9.4 13.8 12.1 20.1 3.9 7.6 10.1 6.2 12.7 7.7 9.4 6.9 9.6 10.6 11.7 7.8 3.1 5.7 13.4 5.7 3.3 4.5 7.0 7.4 8.6 9.7 4.4 5.7 9.6 3.9 5.1 13.0 9.5 5.0 10.6 7.4 6.5 7.0 10.1 3.3 7.2 4.0 17.6 8.5 10.2 5.3 0.0 0.8 0.0 0.4 0.6 0.3 0.6 0.2 0.3 0.6 0.9 0.2 0.3 0.0 0.1 1.6 0.6 0.0 0.4 19.1 19.1 17.3 21.3 18.0 23.5 29.6 29.5 32.1 15.4 22.5 19.4 6.4 19.2 23.6 6.8 12.5 3.4 3.7 5.1 6.2 21.7 5.6 4.7 23.5 8.6 7.0 3.7 14.6 3.7 2.5 5.8 0.0 4.5 15.0 7.7 6.6 6.5 6.6 8.2 9.0 4.6 2.9 8.5 12.2 9.8 2.5 12.6 7.1 7.9 7.5 26.9 9.4 2.9 4.1 10.8 7.8 9.0 7.5 10.2 1.8 9.4 7.4 7.7 3.1 9.0 8.8 5.6 4.4 7.2 3.9 4.7 6.3 3.9 8.9 17.0 0.0 8.9 6.4 9.3 9.8 4.8 3.1 4.1 3.8 8.0 3.2 4.5 CLDN11 "OSP, OTM" ENSG00000013297 "Claudin 11" O75508 3 170418868-170454733 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 130.1;ovary: 95.4;testis: 116.9" "Cell type enhanced" "Detected in many" "Fibroblasts: 56.4;Leydig cells: 105.3;Oligodendrocytes: 394.5;Peritubular cells: 67.7" "Cancer enhanced" "Detected in many" "glioma: 11.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 141.3;ASC TERT1: 174.2;EFO-21: 91.8;HUVEC TERT2: 162.2;TIME: 252.1" "Region enriched" "Detected in all" 5 "white matter: 2084.8" "CAB009789, HPA013166, HPA013657" Enhanced Supported "Lipid droplets,Cell Junctions" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 33: Fibroblasts - ECM organization" "Cell Junctions" "Lipid droplets" "CAB009789: AB_639330, HPA013166: AB_1854821, HPA013657: " "prognostic favorable (6.31e-4)" "unprognostic (3.18e-1)" "unprognostic (2.32e-2)" "unprognostic (5.28e-4)" "unprognostic (3.45e-2)" "unprognostic (4.60e-1)" "unprognostic (5.25e-2)" "unprognostic (5.40e-2)" "unprognostic (2.52e-1)" "unprognostic (1.40e-1)" "unprognostic (1.03e-1)" "unprognostic (5.48e-2)" "unprognostic (8.70e-11)" "unprognostic (2.50e-3)" "unprognostic (1.93e-1)" "unprognostic (6.68e-3)" "unprognostic (2.29e-1)" 29.9 5.4 18.8 0.0 51.7 0.0 15.3 48.7 36.5 6.7 4.4 7.6 0.1 8.1 1.5 5.1 18.0 8.7 7.8 22.7 34.6 6.4 2.2 4.8 0.2 130.1 44.2 95.4 0.8 0.0 20.9 1.2 88.6 11.2 0.3 0.2 5.2 1.0 1.5 6.5 6.6 0.4 52.5 1.2 3.1 116.9 47.4 0.0 1.8 0.7 0.1 13.2 13.2 94.6 0.0 0.0 0.1 0.0 141.3 174.2 0.0 1.2 8.5 11.0 19.6 0.0 19.2 0.0 91.8 14.2 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.0 10.6 42.8 0.0 0.0 61.0 0.0 60.9 0.0 0.4 162.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 4.6 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 252.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.8 51.7 48.7 36.5 22.7 34.6 130.1 44.2 88.6 52.5 47.4 94.6 16.4 0.0 0.6 2.3 0.4 14.4 15.6 1.0 0.0 0.5 5.7 27.7 1.4 1.5 0.1 1.8 0.0 0.9 0.8 0.3 0.0 0.1 8.3 0.5 0.2 37.3 0.0 2.7 1.5 0.0 1.6 56.4 0.0 0.6 0.0 27.2 49.2 1.1 0.9 0.0 2.8 0.0 0.0 1.2 23.8 24.3 105.3 1.1 14.2 24.4 0.0 0.4 0.0 3.5 394.5 0.7 0.0 67.7 0.0 15.4 0.2 0.2 0.2 0.1 0.0 2.9 6.6 11.6 4.1 1.0 10.2 0.8 0.6 1.6 0.1 2.0 CLDN18 SFTPJ ENSG00000066405 "Claudin 18" P56856 3 137998735-138033655 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 50 "lung: 252.2;stomach 1: 724.9" "Group enriched" "Detected in some" 53 "Alveolar cells type 1: 1602.5;Alveolar cells type 2: 431.2;Gastric mucus-secreting cells: 1153.4;Pancreatic endocrine cells: 442.5" "Group enriched" "Detected in some" 11 "pancreatic cancer: 113.6;stomach cancer: 186.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 19 "OE19: 15.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB013010, CAB013243, HPA018446" Enhanced Approved "Cell Junctions" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "CAB013010: AB_2533382, CAB013243: AB_2533383, HPA018446: AB_2669866" "unprognostic (1.03e-1)" "unprognostic (1.49e-1)" "unprognostic (2.93e-1)" "unprognostic (1.04e-2)" "unprognostic (1.41e-1)" "unprognostic (8.51e-2)" "unprognostic (5.14e-4)" "unprognostic (2.00e-1)" "unprognostic (1.29e-1)" "unprognostic (2.60e-1)" "unprognostic (9.54e-2)" "unprognostic (1.38e-2)" "unprognostic (4.42e-5)" "unprognostic (1.66e-1)" "unprognostic (2.26e-1)" "unprognostic (8.26e-2)" "unprognostic (2.95e-1)" 0.3 0.3 0.3 0.4 0.4 0.1 0.2 1.0 0.5 0.4 2.2 0.7 1.5 0.2 0.5 0.6 0.5 3.3 9.7 0.3 0.2 0.2 0.1 252.2 0.0 0.9 0.9 0.5 0.8 0.0 0.5 0.3 0.5 0.2 0.2 0.7 0.3 0.4 0.1 1.1 0.8 0.1 0.7 0.5 724.9 1.3 0.5 0.1 0.1 0.0 0.7 0.2 0.3 0.2 0.1 0.0 0.2 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.7 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 0.5 15.1 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.3 0.1 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.0 0.5 0.3 0.2 0.9 0.9 0.5 0.7 0.5 0.2 0.0 1602.5 431.2 1.0 0.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 17.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.6 0.3 0.2 0.6 0.0 0.0 0.5 11.4 0.0 1.4 1153.4 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 2.0 0.0 1.9 0.0 0.1 0.0 0.0 0.2 442.5 0.0 0.0 1.3 0.0 0.0 0.1 0.7 1.3 0.0 0.9 0.1 15.3 11.9 0.0 0.0 0.0 1.3 0.0 0.0 0.1 CLDN2 ENSG00000165376 "Claudin 2" P57739 X 106900164-106930861 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 114.7;gallbladder: 101.6;kidney: 165.2;seminal vesicle: 90.1" "Cell type enhanced" "Detected in some" "Ductal cells: 77.5;Exocrine glandular cells: 49.1;Hepatocytes: 25.9;Pancreatic endocrine cells: 30.9;Proximal enterocytes: 32.9;Proximal tubular cells: 153.1" "Group enriched" "Detected in many" 5 "colorectal cancer: 53.3;liver cancer: 24.6;pancreatic cancer: 48.5;renal cancer: 87.2;stomach cancer: 30.5" "Region enriched" "Detected in some" 5 "hippocampal formation: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "OE19: 296.4" "Group enriched" "Detected in many" 4 "basal ganglia: 4.5;hippocampal formation: 9.5;pons and medulla: 10.3;thalamus: 8.9" "Region enhanced" "Detected in some" "medulla oblongata: 1.7" "CAB002609, HPA051548" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" "CAB002609: , HPA051548: AB_2681530" "unprognostic (2.31e-1)" "unprognostic (2.62e-1)" "unprognostic (3.99e-1)" "unprognostic (1.73e-1)" "unprognostic (1.30e-2)" "unprognostic (1.42e-2)" "unprognostic (6.07e-2)" "unprognostic (7.47e-3)" "unprognostic (2.24e-1)" "unprognostic (8.67e-2)" "unprognostic (8.83e-2)" "unprognostic (8.15e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (2.12e-1)" "prognostic favorable (1.70e-4)" "unprognostic (9.76e-2)" 0.7 3.0 0.1 2.2 0.1 0.1 0.6 1.6 0.5 0.0 114.7 2.1 21.0 0.1 33.7 0.1 0.3 101.6 0.0 8.4 0.0 165.2 44.2 1.3 0.0 0.2 0.2 0.0 13.2 0.0 0.2 0.0 0.1 1.2 4.5 0.7 0.1 90.1 0.2 0.3 24.5 0.2 0.0 0.0 7.7 0.0 1.3 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.2 27.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 296.4 0.2 0.0 0.0 0.1 46.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.5 8.4 0.0 0.2 0.2 0.1 0.0 1.3 0.1 0.0 0.0 0.0 0.0 2.5 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 14.3 0.0 1.8 0.0 0.0 0.0 0.3 15.6 77.5 0.1 0.0 0.0 0.0 0.0 0.0 0.4 49.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 25.9 0.0 0.0 0.3 2.7 0.0 0.8 0.0 1.4 0.0 0.7 0.0 0.0 1.6 1.6 0.0 1.0 0.2 30.9 3.6 0.0 0.0 0.0 32.9 153.1 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.9 0.0 14.2 0.0 CLDN23 CLDNL ENSG00000253958 "Claudin 23" Q96B33 8 8701937-8704096 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 16.4;stomach 1: 15.6" "Group enriched" "Detected in many" 4 "Distal enterocytes: 418.8;Paneth cells: 449.9" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "myeloid DC: 1.3;plasmacytoid DC: 1.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 7.7;Daudi: 6.4;RT4: 6.7;SK-BR-3: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA061306 Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Plasma membrane, Cell Junctions" "HPA061306: " "unprognostic (1.86e-1)" "unprognostic (1.53e-1)" "prognostic favorable (3.46e-4)" "unprognostic (2.97e-1)" "unprognostic (8.32e-2)" "unprognostic (3.04e-1)" "unprognostic (3.44e-1)" "unprognostic (2.05e-2)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (1.97e-2)" "unprognostic (8.25e-3)" "prognostic favorable (9.65e-8)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (9.59e-2)" "unprognostic (1.33e-3)" 6.2 1.1 0.3 2.3 0.4 0.1 5.7 0.2 0.3 2.4 2.3 16.4 4.1 1.0 1.9 3.3 1.4 1.2 0.7 0.3 0.3 4.5 10.4 4.7 0.3 0.5 0.4 1.6 4.0 2.1 0.9 1.5 0.4 1.3 6.8 0.1 6.8 1.3 0.5 13.5 10.1 0.3 0.4 1.8 15.6 0.5 0.5 0.1 4.9 0.3 0.3 5.0 2.7 0.6 0.1 2.6 0.0 0.1 0.7 0.1 7.7 1.9 1.5 2.0 3.1 1.5 4.2 6.4 0.0 0.1 0.7 2.5 0.0 0.0 0.2 1.3 0.0 0.0 0.7 0.1 3.5 0.0 0.0 1.0 0.8 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.3 0.0 0.2 1.9 0.3 1.3 0.0 0.0 0.0 0.9 6.7 0.3 0.9 2.6 6.8 0.1 0.7 0.9 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.3 0.0 0.9 0.0 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.4 0.2 0.3 0.3 0.3 0.5 0.4 0.4 0.4 0.5 0.6 13.0 9.6 3.1 0.3 1.1 0.1 6.6 4.2 2.2 0.1 6.8 3.4 0.7 30.0 6.9 1.8 0.0 19.1 2.8 418.8 7.9 26.9 0.0 6.0 2.5 3.4 7.7 0.0 0.0 10.7 14.9 3.3 59.7 6.7 4.5 0.8 8.2 10.6 16.8 0.0 0.0 49.9 26.4 2.4 1.4 0.0 0.3 4.6 3.6 1.9 1.4 1.1 0.0 0.0 0.0 28.1 449.9 0.4 0.1 3.3 99.1 4.7 10.3 1.1 6.6 1.5 3.2 0.0 0.0 3.9 0.6 9.4 1.3 0.3 55.2 12.2 CLDN3 "C7orf1, CPE-R2, CPETR2, HRVP1, RVP1" ENSG00000165215 "Claudin 3" O15551 7 73768997-73770270 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 263.1;thyroid gland: 116.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1839.9;Endometrial ciliated cells: 1221.7;Glandular and luminal cells: 1555.7;Intestinal goblet cells: 1471.3;Paneth cells: 2326.0;Proximal enterocytes: 3162.1;Undifferentiated cells: 1266.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 529.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 230.7;PC-3: 47.6;RPMI-8226: 40.5;SCLC-21H: 58.0;T-47d: 105.4" "Region enhanced" "Detected in single" "basal ganglia: 1.5" "Region enhanced" "Detected in many" "midbrain: 9.7" HPA014361 Enhanced Supported "Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA014361: AB_2668982" "unprognostic (1.84e-1)" "unprognostic (4.83e-2)" "unprognostic (2.05e-1)" "unprognostic (5.27e-2)" "unprognostic (2.61e-1)" "unprognostic (1.31e-1)" "unprognostic (2.79e-2)" "unprognostic (8.26e-2)" "unprognostic (3.11e-1)" "unprognostic (1.46e-1)" "unprognostic (2.28e-3)" "unprognostic (1.42e-1)" "prognostic favorable (3.39e-5)" "unprognostic (1.46e-2)" "unprognostic (1.87e-1)" "unprognostic (5.18e-2)" "unprognostic (6.72e-2)" 0.7 0.2 0.2 7.8 0.3 0.2 26.7 4.2 0.3 12.3 37.6 263.1 54.4 7.5 1.4 1.3 29.6 2.2 0.1 1.1 1.2 46.5 40.4 10.7 0.2 1.3 1.9 0.5 96.6 1.5 27.7 1.0 0.6 58.3 17.5 0.4 72.9 8.3 0.1 9.6 169.5 0.8 0.5 0.2 1.4 0.7 0.9 1.0 116.3 0.0 1.2 1.5 0.2 0.2 2.5 3.6 0.0 0.4 0.0 0.0 17.8 0.0 0.0 0.0 0.0 4.2 35.7 0.0 9.9 0.0 0.0 1.0 0.4 0.0 0.0 0.1 4.9 0.0 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 230.7 0.4 1.2 2.1 9.1 47.6 0.1 0.0 40.5 2.1 0.2 58.0 0.7 0.0 33.6 0.0 0.2 105.4 0.0 0.2 0.2 0.6 0.9 0.1 0.2 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 4.2 0.3 1.1 1.2 1.3 1.9 0.6 0.5 0.9 0.2 1.6 38.5 37.8 0.0 13.2 0.1 60.3 43.7 0.0 0.7 289.9 182.5 0.6 287.4 86.3 126.9 4.2 63.9 5.1 1839.9 9.8 297.5 0.0 1221.7 130.5 10.3 606.1 5.3 0.0 19.1 17.7 4.1 16.8 1555.7 28.0 1.5 0.4 40.5 5.1 0.0 0.0 1471.3 116.0 0.3 0.0 0.3 2.5 9.9 10.6 0.0 2.0 11.8 0.0 0.0 0.0 36.7 2326.0 0.0 4.4 433.2 3162.1 58.6 498.4 10.6 0.0 0.0 20.3 0.1 0.3 2.7 0.0 72.4 17.5 0.0 1266.0 607.3 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLDN7 "CEPTRL2, CPETRL2, Hs.84359" ENSG00000181885 "Claudin 7" O95471 17 7259903-7263983 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 341.3;intestine: 341.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 1391.1;Pancreatic endocrine cells: 822.1;Paneth cells: 1276.4;Proximal enterocytes: 1390.9;Urothelial cells: 975.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 84.1;CACO-2: 90.2;CAPAN-2: 173.2;HaCaT: 364.9;MCF7: 129.8;OE19: 139.6;SK-BR-3: 150.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB013063, HPA014703, HPA073662" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "CAB013063: , HPA014703: AB_1846873, HPA073662: " "unprognostic (5.47e-2)" "unprognostic (2.22e-1)" "unprognostic (4.12e-2)" "unprognostic (2.90e-1)" "unprognostic (1.05e-1)" "unprognostic (8.67e-2)" "unprognostic (3.41e-2)" "unprognostic (1.98e-2)" "unprognostic (5.64e-3)" "unprognostic (8.34e-2)" "unprognostic (4.89e-3)" "unprognostic (1.62e-2)" "prognostic favorable (8.96e-11)" "prognostic favorable (4.09e-4)" "unprognostic (1.87e-1)" "prognostic favorable (1.85e-4)" "unprognostic (1.62e-1)" 6.7 8.0 0.4 17.6 0.4 0.2 31.2 0.5 0.6 47.3 0.4 341.0 146.7 4.8 43.9 341.3 41.3 27.4 2.7 0.4 0.4 123.8 40.2 61.8 0.8 0.6 0.5 1.5 108.5 49.0 31.1 14.2 0.6 44.5 128.6 1.1 169.2 30.0 1.5 13.1 248.9 6.2 0.5 5.7 5.2 1.9 0.6 2.4 76.7 0.0 21.2 40.5 96.3 0.9 10.8 1.1 0.2 0.3 0.0 0.6 84.1 0.3 0.3 0.0 0.0 90.2 173.2 0.1 3.2 0.4 0.4 364.9 0.1 11.2 0.0 0.1 1.9 0.1 2.4 0.0 6.5 0.1 0.8 1.5 17.3 0.0 0.6 0.0 8.1 0.1 1.0 0.3 0.1 129.8 0.1 1.2 0.6 139.6 3.4 0.2 0.0 2.5 0.1 0.0 20.4 0.4 1.1 150.2 0.0 6.6 55.0 1.3 16.8 0.2 0.6 0.7 0.2 0.1 0.3 0.1 1.2 0.0 0.3 0.0 0.3 0.0 0.5 0.8 1.3 0.1 0.3 0.8 0.4 0.9 0.9 1.7 0.0 0.7 0.0 0.0 0.3 0.5 0.4 0.4 0.5 0.6 0.4 0.4 0.6 0.5 0.6 0.5 0.6 0.9 4.4 112.2 55.6 0.0 7.4 2.0 295.4 316.3 66.6 0.7 200.4 102.4 0.6 240.2 550.3 321.8 8.4 281.3 3.1 1391.1 39.2 787.5 0.1 210.1 26.6 9.0 326.8 4.0 0.0 790.0 342.7 5.2 15.3 225.5 5.7 0.1 3.6 41.2 33.7 0.0 0.0 741.7 362.2 4.1 6.4 0.2 1.2 11.0 24.9 1.9 11.0 1.6 0.0 0.0 0.0 822.1 1276.4 0.0 0.5 406.5 1390.9 78.6 498.5 6.7 0.0 0.2 38.6 0.4 3.5 366.1 2.6 588.9 10.2 1.0 691.9 975.8 CLDN9 ENSG00000213937 "Claudin 9" O95484 16 3012923-3014505 "Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.8;pituitary gland: 25.2" "Cell type enhanced" "Detected in some" "Cholangiocytes: 15.7;Ductal cells: 9.5;Endometrial ciliated cells: 8.6;Pancreatic endocrine cells: 8.1;Respiratory ciliated cells: 18.1" "Cancer enhanced" "Detected in many" "ovarian cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 4.7;CAPAN-2: 7.3;MCF7: 24.2;SCLC-21H: 20.8" "Not detected" "Not detected" "Not detected" "Not detected" HPA076613 Supported "Vesicles,Cell Junctions" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions" Vesicles "HPA076613: AB_2686808" "unprognostic (7.93e-2)" "unprognostic (1.40e-1)" "unprognostic (1.43e-2)" "prognostic unfavorable (2.24e-6)" "unprognostic (4.91e-2)" "unprognostic (6.04e-2)" "unprognostic (1.13e-1)" "unprognostic (2.75e-1)" "unprognostic (1.64e-2)" "unprognostic (5.06e-2)" "unprognostic (8.97e-3)" "unprognostic (4.51e-2)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.67e-4)" "unprognostic (1.29e-1)" "unprognostic (7.71e-3)" "unprognostic (5.55e-2)" 0.3 0.2 3.3 0.2 4.4 2.7 0.2 10.8 5.6 0.3 2.4 0.5 0.7 0.0 0.0 0.1 1.2 0.2 1.7 3.3 3.6 1.5 5.2 1.2 0.0 5.3 4.0 0.0 6.4 1.4 25.2 0.1 5.6 0.3 0.0 1.9 0.6 0.0 1.2 0.2 0.5 0.0 3.7 2.3 0.5 0.3 4.1 0.3 0.4 0.1 0.0 0.2 0.1 5.2 4.7 0.2 0.0 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 7.3 0.0 0.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 24.2 0.0 2.0 0.1 0.3 0.2 0.0 0.0 0.2 0.2 0.1 20.8 0.0 0.6 0.9 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.3 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.4 10.8 5.6 3.3 3.6 5.3 4.0 5.6 3.7 4.1 5.2 0.0 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 1.3 1.1 0.4 0.3 15.7 2.3 0.0 0.0 0.3 0.0 0.6 0.0 9.5 0.1 8.6 0.3 0.1 1.8 0.0 0.8 1.7 0.9 0.1 0.0 2.7 0.0 0.0 0.4 0.3 0.1 0.0 0.4 0.4 2.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.0 0.0 3.4 8.1 1.5 0.0 0.0 1.2 0.4 0.1 18.1 0.7 0.0 0.0 0.6 0.1 0.2 0.0 0.4 1.1 0.1 0.0 0.6 1.8 CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Group enriched" "Detected in some" 11 "Basal keratinocytes: 18.7;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 22.0;U-937: 54.6" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 3.5 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 57.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.3 0.2 0.3 0.5 0.3 0.5 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 37.1 0.0 0.1 0.0 0.0 0.1 CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Horizontal cells: 5.0;Macrophages: 4.5;monocytes: 4.0;Rod photoreceptor cells: 6.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cell line enhanced" "Detected in single" "AN3-CA: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA056101: " "unprognostic (8.14e-3)" "unprognostic (3.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (4.91e-2)" "unprognostic (5.41e-2)" "unprognostic (3.66e-2)" "unprognostic (2.07e-2)" "unprognostic (9.29e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-2)" "unprognostic (9.59e-2)" "unprognostic (2.44e-1)" 1.5 0.0 0.1 0.6 0.0 0.0 1.1 0.1 0.2 2.7 0.1 0.7 1.6 1.6 0.8 0.7 1.4 1.0 0.7 0.1 0.1 0.6 0.7 0.9 1.2 0.0 0.0 0.6 0.3 0.0 0.6 0.1 0.1 1.5 0.8 17.2 1.7 0.9 1.0 1.3 4.5 1.2 0.0 3.4 0.6 1.0 0.1 0.2 0.3 0.6 0.8 0.7 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.5 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.2 0.3 0.3 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.1 0.0 0.0 1.0 2.3 1.4 0.0 4.5 0.0 0.0 4.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLECL1 DCAL1 ENSG00000184293 "C-type lectin like 1" Q8IZS7 12 9715860-9733299 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 9.9;lymphoid tissue: 31.1" "Group enriched" "Detected in some" 4 "B-cells: 87.0;dendritic cells: 24.0;Hofbauer cells: 22.2;Kupffer cells: 82.3;Langerhans cells: 64.6;Macrophages: 23.9;monocytes: 55.9;Plasma cells: 42.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 120.9" "Lineage enriched" "Detected in many" 5 "B-cells: 120.9" "Group enriched" "Detected in some" 5 "HEL: 49.7;Karpas-707: 66.2;U-698: 173.0;U-937: 95.6" "Low region specificity" "Detected in many" HPA063928 Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Centriolar satellite" "HPA063928: " "unprognostic (2.18e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-3)" "unprognostic (1.90e-3)" "unprognostic (3.66e-1)" "unprognostic (1.90e-3)" "unprognostic (2.83e-1)" "unprognostic (7.55e-4)" "unprognostic (5.10e-2)" "unprognostic (2.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-5)" "unprognostic (3.31e-1)" "unprognostic (2.45e-1)" "unprognostic (6.10e-2)" "unprognostic (7.39e-2)" 1.0 1.6 0.6 9.9 0.9 1.9 2.0 1.4 0.9 0.9 1.3 3.0 2.7 0.9 0.0 0.7 0.8 2.5 0.4 0.6 0.9 0.7 2.1 2.1 24.8 1.8 1.1 0.5 0.2 0.3 0.3 0.7 1.4 0.7 4.3 0.1 1.3 0.5 0.1 0.4 9.9 1.8 1.2 16.2 4.5 0.9 1.1 5.2 0.6 0.2 31.1 3.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.1 0.2 1.2 173.0 0.0 95.6 0.0 2.4 7.9 0.4 4.5 14.4 0.1 120.9 3.9 9.7 18.7 54.3 0.2 1.4 0.3 0.3 15.5 25.4 0.2 5.2 0.6 0.9 1.4 0.9 0.6 0.9 1.8 1.1 1.4 1.2 1.1 1.6 0.3 0.0 0.0 0.0 87.0 2.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.8 0.0 0.0 0.1 24.0 0.1 0.0 0.0 1.0 0.1 0.1 0.3 0.0 4.4 0.0 0.2 0.1 0.6 0.0 0.1 5.1 0.0 0.4 0.4 22.2 0.0 0.0 0.2 0.0 82.3 64.6 1.4 0.3 23.9 12.4 1.0 55.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 6.6 0.1 0.1 0.0 0.2 0.1 1.8 0.3 11.2 0.0 0.0 0.1 CLIC2 "CLCNL2, XAP121" ENSG00000155962 "Chloride intracellular channel 2" O15247 X 155276211-155334657 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 51.2;Alveolar cells type 1: 89.8;Alveolar cells type 2: 54.9;Endothelial cells: 60.4;Erythroid cells: 70.7;Kupffer cells: 73.5;Langerhans cells: 135.0;monocytes: 71.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 18.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "intermediate monocyte: 18.6;myeloid DC: 47.9;non-classical monocyte: 14.2" "Group enriched" "Detected in many" 16 "dendritic cells: 47.9;monocytes: 18.6" "Group enriched" "Detected in some" 5 "HDLM-2: 103.3;K-562: 60.4;Karpas-707: 53.4;RPMI-8226: 92.2" "Low region specificity" "Detected in all" "HPA047381, HPA060101" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 150000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA047381: AB_2680022, HPA060101: AB_2684204" "unprognostic (3.27e-2)" "unprognostic (5.21e-3)" "unprognostic (9.70e-2)" "unprognostic (7.25e-2)" "unprognostic (9.71e-2)" "unprognostic (3.78e-2)" "unprognostic (1.46e-1)" "unprognostic (4.07e-2)" "unprognostic (2.95e-1)" "unprognostic (1.74e-1)" "unprognostic (1.97e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (1.74e-5)" "unprognostic (1.97e-2)" "unprognostic (2.97e-2)" "unprognostic (6.63e-2)" "unprognostic (1.54e-1)" 23.1 7.1 6.9 16.7 7.8 9.8 16.7 6.9 18.1 20.1 7.6 10.9 8.7 22.6 7.8 9.4 12.5 19.0 14.6 7.1 7.0 5.8 12.8 30.6 30.2 7.7 6.9 21.6 3.5 4.6 4.5 9.3 7.4 4.6 13.6 2.4 6.2 6.3 4.4 6.1 10.3 17.7 7.7 50.1 8.5 3.2 8.5 14.5 31.8 14.3 25.6 15.9 10.7 7.8 0.7 0.0 1.0 0.9 1.0 4.7 0.0 0.2 2.8 0.0 0.4 0.0 0.2 0.1 0.4 0.0 0.2 0.1 0.3 0.0 0.0 103.3 0.5 16.4 0.3 0.0 0.0 0.4 0.6 1.4 0.0 0.0 0.1 0.5 0.1 0.5 60.4 53.4 0.3 0.2 0.1 1.3 0.2 0.1 0.4 0.4 0.0 92.2 0.2 0.2 0.7 0.9 0.0 0.1 0.4 0.2 0.0 1.0 0.0 5.3 1.6 2.0 0.9 3.3 4.6 0.0 2.7 2.6 1.7 0.0 3.5 0.2 0.0 18.6 0.3 0.0 0.1 0.1 47.9 0.0 0.0 0.0 1.4 2.0 14.2 5.2 0.0 2.1 6.9 7.8 6.9 18.1 7.1 7.0 7.7 6.9 7.4 7.7 8.5 7.8 51.2 89.8 54.9 3.9 1.1 13.3 0.8 0.2 2.2 1.2 0.7 1.3 3.2 0.0 5.8 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.5 11.3 60.4 1.2 70.7 8.6 0.2 0.1 25.6 0.5 0.4 3.8 0.5 27.1 1.2 4.7 0.0 7.0 0.6 0.0 73.5 135.0 1.1 13.7 34.5 17.8 8.4 71.4 0.2 0.0 3.0 2.4 0.1 0.0 9.4 2.0 0.5 0.0 0.6 1.5 0.3 6.6 2.5 4.6 0.3 0.3 0.4 13.8 0.0 2.6 5.2 0.1 1.9 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLTB Lcb ENSG00000175416 "Clathrin light chain B" P09497 5 176392501-176416539 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Pancreatic endocrine cells: 1839.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HBEC3-KT: 704.2;MCF7: 641.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003692, HPA036458" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" Vesicles "Plasma membrane, Cytosol" "CAB003692: AB_425372, HPA036458: AB_2675136" "unprognostic (1.09e-1)" "unprognostic (1.73e-1)" "unprognostic (4.51e-2)" "unprognostic (1.46e-1)" "unprognostic (1.34e-2)" "unprognostic (1.60e-1)" "unprognostic (3.54e-3)" "unprognostic (1.83e-2)" "unprognostic (1.74e-2)" "unprognostic (1.93e-1)" "unprognostic (7.42e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (7.89e-5)" "unprognostic (3.55e-1)" "unprognostic (7.50e-2)" "unprognostic (8.59e-2)" "unprognostic (1.60e-2)" 102.9 133.6 125.8 50.1 125.1 40.6 82.9 117.8 176.7 180.4 125.3 133.9 92.3 85.9 23.2 473.7 82.4 34.1 320.8 130.8 129.6 90.4 82.5 96.5 32.9 136.9 122.8 107.2 68.2 70.1 112.8 57.5 138.1 88.1 45.5 37.9 128.6 44.4 322.5 453.1 99.7 41.2 114.5 68.7 123.3 38.9 127.9 43.7 69.5 120.8 58.5 106.2 300.8 133.6 229.1 107.6 29.9 128.2 65.7 49.2 244.4 286.3 110.9 178.6 127.0 140.3 103.9 49.6 165.0 130.2 71.8 213.3 51.4 704.2 69.7 341.7 95.3 33.6 163.3 87.7 102.9 53.2 85.6 52.6 241.5 98.1 114.7 36.0 84.7 39.2 65.2 123.4 100.3 641.9 84.5 81.1 24.4 189.5 158.2 91.3 52.9 165.2 95.6 92.0 127.7 43.7 136.6 148.0 103.6 34.7 61.4 101.9 185.2 64.0 96.3 117.5 165.1 96.5 73.3 68.5 51.4 112.7 74.4 6.6 19.7 61.7 13.6 15.8 7.0 5.9 11.9 13.2 20.0 10.1 10.0 10.0 36.6 15.0 20.8 16.1 24.9 8.1 125.8 125.1 117.8 176.7 130.8 129.6 136.9 122.8 138.1 114.5 127.9 133.6 113.7 57.7 19.8 8.5 54.7 634.0 238.7 155.7 180.4 310.5 105.5 124.6 208.5 72.9 93.4 82.8 64.6 141.1 82.3 794.5 135.0 324.7 9.5 58.4 72.7 102.2 151.8 43.6 25.4 453.1 586.9 136.7 193.2 85.2 48.2 40.8 70.3 96.3 111.9 336.5 24.1 348.5 114.0 80.7 226.1 13.7 122.1 88.4 220.5 6.5 85.7 136.1 107.1 8.0 15.2 1839.9 786.9 129.8 76.4 391.4 545.7 269.7 49.6 64.3 78.9 79.6 161.4 15.9 29.1 415.6 803.0 386.5 81.3 151.2 289.7 436.0 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CMTM4 CKLFSF4 ENSG00000183723 "CKLF like MARVEL transmembrane domain containing 4" Q8IZR5 16 66614750-66696743 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 45.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 68.0;Granulosa cells: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014704, HPA023890" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Golgi apparatus, Vesicles, Plasma membrane" "HPA014704: AB_1847005, HPA023890: AB_1847007" "unprognostic (2.65e-3)" "unprognostic (1.16e-1)" "unprognostic (6.17e-3)" "unprognostic (3.43e-1)" "unprognostic (5.13e-1)" "unprognostic (8.30e-2)" "unprognostic (2.88e-2)" "unprognostic (2.65e-1)" "unprognostic (3.35e-3)" "unprognostic (6.06e-3)" "unprognostic (2.07e-2)" "unprognostic (3.08e-1)" "prognostic favorable (4.72e-9)" "unprognostic (1.41e-1)" "unprognostic (2.31e-1)" "unprognostic (4.94e-2)" "unprognostic (1.00e-1)" 4.5 5.0 36.4 2.7 34.1 2.5 5.7 32.8 34.5 3.9 28.3 16.1 11.9 4.4 20.1 6.0 10.6 2.9 4.1 43.1 37.1 26.3 4.1 8.4 0.6 42.1 41.7 3.4 19.2 32.7 14.4 2.1 35.4 7.7 12.6 7.8 11.1 3.8 3.3 7.7 12.9 3.4 41.8 2.0 31.4 6.9 45.5 0.5 38.6 2.1 1.1 3.2 4.1 41.6 16.0 12.9 7.8 19.1 2.6 4.2 31.7 6.6 5.9 3.5 5.6 24.2 17.7 0.7 10.8 3.9 4.8 20.0 19.7 7.8 5.2 1.3 17.2 1.7 5.3 15.2 5.6 1.4 3.0 6.7 13.4 4.2 8.1 11.9 2.0 2.3 8.0 4.1 5.1 18.5 0.1 3.2 8.7 28.6 8.6 3.5 10.6 4.9 15.2 14.2 17.9 7.1 27.4 14.6 9.3 5.6 15.3 3.4 4.3 6.5 7.0 1.8 6.6 1.4 3.3 0.7 8.1 3.2 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 36.4 34.1 32.8 34.5 43.1 37.1 42.1 41.7 35.4 41.8 45.5 41.6 2.6 22.4 11.1 32.7 0.8 5.2 8.8 21.9 4.6 9.5 23.5 10.8 7.1 15.7 19.3 23.9 8.4 5.0 1.6 51.7 13.7 15.9 1.9 20.7 2.7 4.3 39.0 0.8 68.0 24.0 29.6 3.5 27.5 12.3 4.5 67.6 1.8 6.1 2.4 30.3 37.7 24.1 20.3 2.8 0.9 3.0 2.5 1.9 3.6 7.5 4.4 24.2 0.0 37.7 51.3 30.8 19.5 3.0 0.6 29.0 30.7 19.9 40.0 11.1 6.6 3.1 8.8 6.4 7.7 7.5 5.5 2.9 0.9 2.5 43.4 19.4 CMTM7 "CKLFSF7, FLJ30992" ENSG00000153551 "CKLF like MARVEL transmembrane domain containing 7" Q96FZ5 3 32391698-32483067 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 102.3;Ductal cells: 105.6;Hofbauer cells: 120.3;Kupffer cells: 110.7;Langerhans cells: 102.8;monocytes: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 135.4;hTERT-RPE1: 135.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077409 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA077409: AB_2686838" "unprognostic (2.27e-3)" "unprognostic (3.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.15e-1)" "unprognostic (5.42e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (3.03e-2)" "unprognostic (3.92e-2)" "unprognostic (2.60e-1)" "unprognostic (6.55e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.00e-6)" "unprognostic (5.86e-2)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (3.12e-2)" 22.8 10.4 7.5 20.7 7.7 43.7 32.6 8.6 12.9 15.2 8.7 8.4 5.3 11.1 10.9 3.9 38.7 16.0 10.1 7.3 8.2 22.1 10.1 33.0 32.2 8.9 8.3 5.5 19.9 4.0 3.7 19.2 9.2 12.1 9.3 0.6 13.1 19.9 4.0 10.1 18.3 10.5 8.7 49.3 13.4 8.6 9.5 46.1 20.5 3.1 31.4 24.1 7.2 10.8 0.4 15.8 32.8 40.2 29.8 29.0 93.4 15.5 18.0 26.5 24.3 18.0 135.4 0.1 46.7 18.1 33.0 17.4 40.6 69.1 23.2 0.0 32.8 18.5 0.1 40.6 120.8 4.7 29.0 31.0 9.0 27.2 42.6 135.1 60.0 0.2 15.8 40.9 19.6 0.4 0.2 42.9 39.7 7.0 71.7 90.5 12.3 85.0 37.7 30.9 1.6 33.9 2.0 2.6 80.8 13.9 21.3 48.7 36.2 25.3 25.5 27.9 54.4 11.6 4.6 0.2 9.3 57.9 54.2 32.4 198.7 110.8 21.3 196.8 12.7 44.2 72.1 44.2 106.8 34.7 76.5 54.1 77.3 21.6 173.6 45.0 164.1 112.6 7.5 7.7 8.6 12.9 7.3 8.2 8.9 8.3 9.2 8.7 9.5 10.8 10.3 25.6 16.7 1.0 65.5 9.8 20.2 102.3 1.8 0.5 63.4 86.0 2.1 28.6 51.9 18.4 0.0 22.2 25.0 2.0 0.0 105.6 0.2 17.4 12.8 24.2 17.3 11.6 0.5 15.5 10.0 15.2 26.0 33.1 29.8 29.0 20.7 1.3 120.3 1.7 1.4 4.4 40.7 110.7 102.8 1.2 1.5 77.2 24.9 20.6 108.1 1.4 12.3 1.0 0.3 91.8 8.1 1.2 62.9 42.0 1.2 27.5 23.3 0.2 6.6 1.2 13.5 1.2 10.4 0.9 5.5 6.8 57.4 6.1 2.8 16.3 CMTR2 "AFT, FLJ11171, FTSJD1, MTr2" ENSG00000180917 "Cap methyltransferase 2" Q8IYT2 16 71281389-71289715 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "mRNA capping, mRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 95.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041700, HPA048265" Uncertain Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear speckles" "HPA041700: AB_2677623, HPA048265: AB_2680334" "unprognostic (1.27e-1)" "unprognostic (2.49e-2)" "unprognostic (2.94e-3)" "unprognostic (1.43e-1)" "unprognostic (6.30e-2)" "unprognostic (3.82e-2)" "unprognostic (1.93e-3)" "unprognostic (2.86e-2)" "unprognostic (7.93e-2)" "unprognostic (3.41e-1)" "unprognostic (1.85e-2)" "unprognostic (7.39e-2)" "prognostic favorable (4.97e-5)" "unprognostic (9.55e-2)" "unprognostic (5.99e-2)" "unprognostic (1.54e-1)" "unprognostic (5.34e-2)" 6.7 8.8 4.0 10.3 4.6 7.2 15.9 4.6 4.2 7.6 8.0 10.1 14.9 8.5 12.2 14.3 9.0 9.4 7.0 3.2 4.7 12.5 14.3 11.4 14.4 5.1 4.4 11.2 8.1 10.7 7.8 10.6 4.8 10.8 10.4 7.3 13.3 8.0 5.7 10.3 14.2 9.0 5.2 13.6 10.0 13.8 4.9 10.7 14.1 5.7 17.9 9.7 7.6 6.6 17.8 11.6 23.2 19.5 18.9 15.3 10.6 14.9 18.2 17.4 18.4 10.6 26.5 10.0 18.4 13.7 18.9 19.4 11.1 14.2 24.9 10.5 7.9 22.3 13.1 8.3 20.3 16.8 37.7 12.7 24.7 15.4 17.9 12.8 18.5 22.2 11.6 6.6 31.1 15.9 18.8 23.1 11.0 14.2 6.7 28.5 10.2 24.5 16.3 19.5 12.0 12.8 15.1 12.2 15.4 10.3 18.0 10.4 18.7 21.1 15.1 15.5 11.4 13.3 17.6 21.3 14.7 14.6 16.8 22.6 9.6 9.2 10.8 10.3 13.2 13.1 10.6 11.7 13.7 12.0 11.4 11.1 0.7 16.6 6.9 3.9 9.8 11.4 4.0 4.6 4.6 4.2 3.2 4.7 5.1 4.4 4.8 5.2 4.9 6.6 11.4 3.2 11.8 13.7 28.1 14.1 14.5 10.7 15.9 20.3 23.9 13.7 8.6 20.0 9.4 16.5 31.3 24.2 30.2 25.8 7.9 12.2 95.6 12.6 15.1 14.6 18.6 17.0 9.9 9.7 12.7 11.5 15.8 11.5 8.2 26.1 18.9 32.7 16.1 15.2 10.3 20.5 18.3 18.0 11.4 30.9 16.8 13.6 1.8 21.5 17.8 12.1 51.5 17.6 21.5 12.9 15.2 12.4 17.9 13.5 46.3 17.7 6.5 25.5 6.6 11.1 10.1 26.1 13.8 22.0 24.3 26.4 20.0 21.8 17.9 18.2 CMYA5 "C5orf10, DKFZp451G223, SPRYD2, TRIM76" ENSG00000164309 "Cardiomyopathy associated 5" Q8N3K9 5 79689836-79800240 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "skeletal muscle: 623.5;tongue: 799.5" "Cell type enriched" "Detected in many" 15 "Cardiomyocytes: 3425.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 1.3;RT4: 1.5;THP-1: 5.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA074081, HPA077831" Enhanced Approved "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles, Cytosol" "Vesicles, Plasma membrane" "HPA074081: , HPA077831: " "unprognostic (5.53e-2)" "unprognostic (9.91e-3)" "unprognostic (1.21e-2)" "unprognostic (1.49e-2)" "unprognostic (9.01e-4)" "unprognostic (7.00e-2)" "unprognostic (7.39e-2)" "unprognostic (1.20e-1)" "unprognostic (1.64e-1)" "unprognostic (1.75e-1)" "unprognostic (5.04e-1)" "unprognostic (1.93e-1)" "unprognostic (1.93e-2)" "unprognostic (6.30e-3)" "unprognostic (3.88e-2)" "unprognostic (7.69e-2)" "unprognostic (9.74e-2)" 0.9 0.1 1.4 0.2 1.4 0.0 3.9 1.2 2.1 1.7 3.1 1.3 0.1 5.9 4.6 6.6 2.1 0.9 155.8 0.6 0.6 2.5 1.2 0.5 0.0 1.6 2.0 14.6 0.3 3.6 2.0 1.1 1.1 6.1 0.2 1.7 6.1 2.1 623.5 2.2 0.4 4.6 1.1 0.0 0.6 0.5 1.7 0.9 2.3 799.5 0.1 2.1 1.2 0.8 0.0 0.0 0.0 0.1 0.5 0.4 0.6 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 1.0 5.4 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 1.4 1.2 2.1 0.6 0.6 1.6 2.0 1.1 1.1 1.7 0.8 2.7 9.6 2.8 69.5 0.4 1.3 17.9 2.9 4.6 2.0 24.4 46.6 3425.2 5.7 12.2 25.8 0.0 21.4 1.3 0.4 17.6 0.7 0.3 29.3 7.2 19.7 1.8 0.0 32.9 0.4 2.9 113.7 3.6 55.2 1.3 2.5 0.4 2.3 2.1 217.0 10.7 0.2 8.2 0.6 1.6 2.3 14.9 1.4 0.0 6.5 0.1 8.8 2.1 156.3 2.9 0.6 0.2 13.5 0.6 4.8 0.0 15.4 6.2 3.0 0.0 165.6 23.1 2.5 2.0 2.2 5.4 32.8 1.2 1.7 0.2 18.1 CNGA1 "CNCG, CNCG1, CNG1, RCNC1, RCNCa, RP49" ENSG00000198515 "Cyclic nucleotide gated channel subunit alpha 1" P29973 4 47935977-48016681 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 11 "retina: 264.4" "Cell type enriched" "Detected in many" 6 "Rod photoreceptor cells: 1139.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 4.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.2;RT4: 7.2;U-2 OS: 3.0" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Not detected" "Not detected" HPA076168 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 79: Retina - Phototransduction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Plasma membrane" Nucleoplasm "HPA076168: AB_2686781" "unprognostic (2.68e-2)" "unprognostic (4.90e-2)" "unprognostic (1.33e-1)" "unprognostic (8.59e-2)" "unprognostic (2.07e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-2)" "unprognostic (3.85e-2)" "unprognostic (1.12e-1)" "unprognostic (1.98e-2)" "unprognostic (3.18e-1)" "unprognostic (2.91e-1)" "unprognostic (5.48e-6)" "unprognostic (1.86e-1)" "unprognostic (1.04e-1)" "unprognostic (4.66e-2)" "unprognostic (8.23e-2)" 3.3 0.4 0.5 0.8 1.4 0.3 1.5 1.6 0.9 1.0 0.6 3.6 2.2 0.4 9.3 9.0 4.1 1.1 0.4 0.7 0.8 2.4 23.5 0.3 0.1 0.4 0.3 0.1 0.8 4.1 0.3 1.0 0.4 2.6 2.4 264.4 4.3 1.7 5.0 5.1 6.3 0.3 0.1 3.4 2.8 0.4 0.7 0.3 0.7 1.3 0.5 3.7 1.9 0.6 2.3 0.9 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.2 2.0 9.2 0.1 0.5 0.0 2.7 1.4 0.2 0.3 0.1 0.0 0.6 0.0 0.2 0.8 0.0 0.1 0.2 0.0 0.4 0.0 0.0 0.9 0.0 0.8 0.7 0.5 0.2 0.9 0.0 0.1 0.4 1.1 2.2 0.1 0.0 0.1 0.4 7.2 0.3 0.0 0.2 0.5 0.1 0.2 0.9 0.0 0.3 0.2 3.0 0.1 0.1 0.7 0.8 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.2 0.3 0.0 0.5 0.0 0.0 0.5 1.4 1.6 0.9 0.7 0.8 0.4 0.3 0.4 0.1 0.7 0.6 7.3 0.0 0.0 0.7 0.1 0.1 1.8 0.5 0.6 97.7 8.7 1.8 0.7 5.7 3.4 62.5 91.8 0.0 0.0 10.6 0.0 10.1 0.4 2.5 0.4 8.7 0.0 2.7 1.2 6.6 0.0 0.3 0.0 3.6 0.0 0.0 0.0 38.0 1.7 45.4 1.1 4.0 0.0 0.8 0.0 0.1 0.3 0.5 0.0 7.5 0.0 163.9 0.0 0.0 0.2 2.1 16.4 0.0 0.0 3.7 24.5 0.4 0.8 1139.7 0.0 0.6 17.1 0.6 1.3 10.3 2.7 0.3 0.2 0.1 4.7 35.1 CNGA4 "CNCA2, CNG5, CNGB2, OCNC2, OCNCb" ENSG00000132259 "Cyclic nucleotide gated channel subunit alpha 4" Q8IV77 11 6234765-6244479 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Olfaction, Sensory transduction, Transport" "Ion channel, Ligand-gated ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 17.3;testis: 6.1" "Cell type enhanced" "Detected in some" "Astrocytes: 9.1;Early spermatids: 5.0;Endometrial ciliated cells: 2.7;Excitatory neurons: 3.0;Inhibitory neurons: 2.5;Late spermatids: 3.6;Oligodendrocytes: 3.1;Respiratory ciliated cells: 3.5" "Cancer enriched" "Detected in single" 6 "endometrial cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA074128 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA074128: " "unprognostic (1.11e-2)" "unprognostic (4.32e-2)" "unprognostic (2.69e-3)" "prognostic favorable (1.48e-4)" "unprognostic (4.96e-2)" "unprognostic (1.09e-1)" "unprognostic (2.01e-3)" "unprognostic (1.89e-1)" "unprognostic (8.51e-2)" "unprognostic (5.51e-2)" "unprognostic (1.83e-2)" "unprognostic (8.70e-2)" "unprognostic (1.03e-3)" "unprognostic (3.84e-2)" "unprognostic (3.47e-2)" "unprognostic (8.11e-2)" "unprognostic (3.55e-3)" 0.1 0.2 1.2 0.2 1.3 0.4 0.2 1.3 1.2 0.7 0.7 0.2 0.3 0.6 0.2 0.2 17.3 0.2 0.1 1.4 1.4 0.4 0.2 1.4 0.2 2.8 3.8 0.4 0.4 0.0 0.7 0.0 2.5 0.2 0.1 1.1 0.1 0.5 0.0 0.3 0.2 0.1 1.8 0.3 0.2 6.1 1.2 0.3 0.2 0.0 0.2 0.2 0.2 1.9 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 1.3 1.2 1.4 1.4 2.8 3.8 2.5 1.8 1.2 1.9 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.6;retina: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 497.7;Inhibitory neurons: 143.6;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 4.0;NTERA-2: 8.9;PC-3: 4.8;RH-30: 8.2;U-251 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" "HPA001502: AB_1078542" "unprognostic (1.33e-2)" "unprognostic (1.00e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-4)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-2)" "unprognostic (3.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.35e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" 1.5 2.6 8.4 0.3 12.2 0.2 1.4 22.6 16.4 1.0 0.0 0.7 0.1 0.3 0.5 0.0 1.3 0.1 0.8 20.3 0.0 0.1 0.7 1.2 0.9 0.0 0.0 0.6 2.5 0.0 1.6 0.1 0.0 0.7 0.0 17.9 0.5 0.1 4.7 0.8 0.6 0.1 0.0 0.5 1.2 0.6 0.0 0.9 0.9 1.3 1.0 0.6 0.9 5.3 0.0 5.9 4.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 2.0 0.0 8.9 0.0 4.8 0.0 8.2 0.0 0.0 0.0 3.9 1.6 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.1 1.9 0.0 5.3 3.1 0.0 3.4 0.8 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.9 0.8 0.2 0.0 0.0 0.0 0.0 0.2 0.1 8.4 12.2 22.6 16.4 20.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.3 16.0 1.3 111.7 9.0 1.3 0.5 0.0 1.2 17.8 0.3 0.6 5.7 1.5 5.6 0.0 20.9 0.1 2.1 0.4 0.0 0.3 0.3 1.0 13.6 0.3 0.0 0.8 497.7 2.3 0.0 6.7 0.0 1.3 1.3 1.0 0.0 2.1 0.1 23.5 143.6 0.5 0.0 0.0 2.6 0.0 0.6 0.2 0.0 15.9 0.2 12.7 0.0 93.5 10.6 0.6 0.1 1.5 3.1 2.0 1.3 0.3 0.0 86.1 0.0 0.6 0.9 6.0 7.7 0.1 1.8 0.0 2.9 1.5 0.4 0.0 CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;testis: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 103.1;Excitatory neurons: 69.9;Horizontal cells: 50.5;Inhibitory neurons: 89.5;Late spermatids: 88.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.6;BJ hTERT+: 7.4;BJ hTERT+ SV40 Large T+ RasG12V: 11.3;HAP1: 8.7;OE19: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA040408: AB_10793963" "unprognostic (9.04e-4)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-4)" "unprognostic (4.08e-3)" "unprognostic (9.51e-2)" "unprognostic (6.01e-2)" "unprognostic (2.27e-2)" "unprognostic (6.03e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-2)" "unprognostic (2.45e-1)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" 0.2 1.1 9.9 0.2 9.9 0.0 0.5 5.4 16.7 1.8 0.0 0.7 0.4 0.9 1.7 0.8 1.0 0.3 0.1 7.3 7.3 1.7 0.2 0.1 0.0 3.6 2.9 2.6 1.1 0.6 3.6 0.0 3.5 1.7 0.4 5.2 0.8 0.8 0.0 1.2 0.6 0.4 2.0 0.1 0.6 9.8 4.7 0.1 0.1 0.1 0.1 1.7 1.4 10.1 0.0 19.6 0.0 0.0 0.0 0.0 0.0 2.8 7.4 6.7 11.3 0.0 4.4 0.0 0.0 1.4 0.1 1.7 8.7 0.0 4.8 0.0 0.9 1.9 2.8 3.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.4 2.7 0.3 0.0 0.9 7.7 0.8 0.0 0.0 0.0 0.9 0.0 2.2 6.1 2.0 0.4 1.0 0.5 0.0 0.0 0.0 0.6 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 9.9 5.4 16.7 7.3 7.3 3.6 2.9 3.5 2.0 4.7 10.1 0.6 0.0 0.0 4.6 0.0 2.3 3.3 0.1 5.2 25.3 0.7 2.8 1.4 0.0 0.2 1.8 14.6 0.0 0.0 0.0 0.0 0.6 103.1 0.5 1.0 0.4 0.0 0.8 69.9 1.5 0.0 1.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 50.5 89.5 0.1 0.0 0.0 0.8 88.0 2.1 0.3 1.8 4.7 0.1 1.3 0.0 10.6 2.2 2.0 0.3 2.6 0.0 5.9 0.1 0.7 0.6 3.4 0.0 2.0 0.5 1.9 1.6 1.5 1.0 0.0 0.2 1.2 0.1 2.4 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966763-41977740 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1395.7" "Cell type enriched" "Detected in all" 4 "Oligodendrocytes: 555.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 149.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "white matter: 1789.4" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 46000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 34.4 33.5 493.1 31.2 889.6 23.4 29.6 715.5 681.5 41.7 193.5 56.9 21.4 33.5 36.7 63.4 28.9 32.6 25.3 505.1 577.0 58.1 44.8 21.7 35.7 839.4 761.8 32.2 27.8 23.7 28.1 23.5 793.8 41.5 18.4 20.5 47.2 37.2 26.3 34.3 31.4 30.3 644.6 25.8 29.8 16.7 791.1 31.2 24.7 22.2 35.1 37.3 40.5 1395.7 56.9 92.4 85.8 106.6 71.7 67.2 38.5 70.1 102.5 171.1 191.5 73.0 49.6 59.0 54.3 88.5 88.1 95.0 58.3 44.6 59.0 59.7 76.8 56.7 59.3 127.7 76.9 56.7 49.6 111.0 31.5 94.1 22.8 61.9 79.4 58.0 42.4 46.4 60.6 35.1 148.5 50.9 20.7 29.8 66.5 91.4 126.7 58.7 45.7 55.7 50.9 69.5 85.7 127.0 155.5 41.6 57.2 82.3 80.2 66.6 73.7 92.3 81.9 53.4 66.6 47.5 66.1 42.9 266.4 18.7 38.2 23.4 21.5 40.7 17.2 28.0 18.8 17.4 33.8 19.2 16.6 19.6 7.7 23.5 34.0 149.4 22.4 33.0 493.1 889.6 715.5 681.5 505.1 577.0 839.4 761.8 793.8 644.6 791.1 1395.7 26.6 16.0 12.7 14.4 19.0 16.7 17.5 10.4 16.5 22.0 29.5 24.0 13.0 20.0 19.5 35.0 6.2 30.6 53.2 39.9 125.2 46.3 1.3 19.1 27.1 24.8 19.7 25.2 6.8 41.7 50.2 27.7 17.9 21.3 9.5 20.2 20.3 32.3 39.8 50.5 9.5 16.2 18.3 17.0 14.5 4.0 38.8 20.3 55.2 14.0 25.0 84.7 23.7 45.2 555.6 35.5 19.0 36.1 27.8 21.7 19.0 80.5 12.8 25.4 32.9 36.6 29.4 5.1 16.0 30.9 18.9 13.0 16.9 33.3 20.6 17.4 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 COBL KIAA0633 ENSG00000106078 "Cordon-bleu WH2 repeat protein" O75128 7 51016212-51316818 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 118.2;skeletal muscle: 131.6;tongue: 107.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 198.7;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 548.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 33.7;HeLa: 57.0;OE19: 53.4;RPMI-8226: 45.5;SuSa: 32.6;U-266/84: 34.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019033, HPA019167" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cell Junctions" "HPA019033: AB_2083648, HPA019167: AB_1847070" "unprognostic (8.09e-2)" "unprognostic (1.08e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-3)" "unprognostic (3.13e-1)" "unprognostic (5.33e-3)" "unprognostic (2.90e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.21e-12)" "unprognostic (7.64e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-1)" "unprognostic (5.41e-3)" 3.0 1.0 83.8 1.4 96.7 0.0 14.8 62.0 91.1 4.8 41.6 13.3 18.9 2.2 2.1 13.6 19.1 5.8 54.8 81.8 67.9 12.9 19.6 13.8 0.2 76.6 88.3 2.8 18.4 31.5 12.8 4.7 69.2 14.4 10.9 23.3 47.3 4.2 131.6 27.5 21.5 2.7 66.6 0.3 17.6 3.0 89.8 1.3 8.3 107.9 1.0 1.8 5.8 118.2 12.4 8.8 0.2 0.3 0.0 0.0 33.7 0.0 0.0 0.0 0.0 24.1 18.2 0.0 0.9 0.0 1.4 21.1 12.0 0.0 0.0 0.0 9.6 0.0 57.0 4.7 0.0 0.0 0.1 1.5 2.3 0.0 0.0 0.0 0.0 1.6 6.5 0.2 0.2 7.9 0.1 0.1 9.0 53.4 8.0 0.1 0.5 45.5 17.4 0.0 11.0 0.2 3.2 26.2 3.9 32.6 16.6 0.1 0.0 0.0 9.8 0.3 0.9 0.0 34.1 0.1 0.1 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 83.8 96.7 62.0 91.1 81.8 67.9 76.6 88.3 69.2 66.6 89.8 118.2 1.4 38.5 19.6 48.0 1.0 17.8 3.4 1.2 4.0 2.3 38.0 34.7 76.2 28.6 13.2 9.2 58.4 23.3 4.6 59.4 0.0 21.5 3.8 65.9 3.3 2.2 18.6 0.0 198.7 9.7 9.2 7.7 35.7 74.6 10.1 4.6 0.4 29.7 2.2 0.0 96.6 35.2 4.1 0.8 1.7 3.1 0.6 0.9 16.0 10.3 1.1 94.4 0.0 353.9 548.8 23.2 35.0 0.4 0.2 25.3 76.8 18.6 31.4 73.6 0.0 10.5 1.5 0.7 8.8 6.8 35.7 40.2 1.7 11.2 14.4 7.3 COBLL1 KIAA0977 ENSG00000082438 "Cordon-bleu WH2 repeat protein like 1" Q53SF7 2 164653624-164843679 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 107.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 218.8;Cone photoreceptor cells: 250.2;Microglial cells: 351.3;Syncytiotrophoblasts: 331.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 15.0;naive B-cell: 9.4;plasmacytoid DC: 8.1" "Group enriched" "Detected in many" 13 "B-cells: 15.0;dendritic cells: 8.1" "Cell line enhanced" "Detected in many" "Karpas-707: 62.6;RPTEC TERT1: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044933, HPA053344" Enhanced Approved "Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "HPA044933: AB_2679148, HPA053344: AB_2682123" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (6.82e-2)" "unprognostic (2.38e-2)" "unprognostic (3.65e-2)" "unprognostic (1.03e-1)" "unprognostic (4.49e-3)" "unprognostic (1.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.76e-2)" "unprognostic (3.65e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.27e-13)" "unprognostic (1.56e-1)" "unprognostic (1.52e-1)" "unprognostic (2.47e-1)" "unprognostic (1.42e-1)" 35.1 51.4 9.5 7.4 8.5 4.1 13.8 6.4 9.2 10.1 28.7 8.0 10.7 4.6 15.6 32.6 4.8 12.3 7.2 6.6 7.1 68.8 107.6 18.2 12.8 8.9 7.9 12.5 43.7 10.9 5.0 50.9 9.4 27.4 7.8 56.8 17.9 28.0 3.3 16.9 7.8 7.4 6.8 9.9 30.0 2.0 12.8 4.8 18.4 7.2 16.2 22.6 16.4 6.3 10.7 2.2 5.9 0.0 7.1 1.3 11.9 34.0 13.3 4.7 5.6 8.9 4.3 1.0 6.9 3.2 5.0 38.4 26.2 21.3 5.6 2.9 10.7 10.5 9.5 36.3 10.2 0.0 0.0 1.8 19.8 1.0 27.6 5.8 21.1 1.3 0.0 62.6 7.5 12.5 0.3 0.1 2.9 25.9 12.8 1.3 22.4 10.4 63.1 36.0 14.4 5.8 16.1 14.7 4.6 11.4 10.7 0.0 9.5 11.3 9.7 3.8 8.3 24.3 10.0 3.6 4.7 0.0 11.6 0.0 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.8 0.0 8.1 0.0 0.4 9.5 8.5 6.4 9.2 6.6 7.1 8.9 7.9 9.4 6.8 12.8 6.3 56.4 70.5 66.5 7.5 102.5 97.3 54.3 14.5 30.7 21.6 22.4 22.4 9.3 30.0 26.0 218.8 250.2 52.1 40.8 11.3 62.6 25.5 0.1 24.6 12.2 47.1 22.2 22.5 23.7 33.8 71.3 35.0 53.5 19.5 34.1 9.0 6.1 127.9 8.7 3.3 30.9 11.0 24.4 3.9 9.0 1.3 14.6 3.7 19.6 351.3 0.7 144.5 0.0 5.0 1.6 29.8 4.9 7.9 154.8 46.0 12.6 28.6 12.4 190.2 46.0 8.6 71.2 0.6 2.7 69.0 70.3 331.4 8.3 8.0 10.0 75.6 COG3 SEC34 ENSG00000136152 "Component of oligomeric golgi complex 3" Q96JB2 13 45464898-45536701 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040353, HPA054470" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA040353: AB_10794027, HPA054470: AB_2732585" "unprognostic (1.75e-1)" "unprognostic (3.03e-3)" "unprognostic (1.75e-1)" "unprognostic (4.04e-3)" "unprognostic (9.69e-2)" "unprognostic (2.86e-2)" "unprognostic (2.18e-2)" "unprognostic (4.46e-2)" "unprognostic (2.51e-2)" "prognostic unfavorable (9.53e-4)" "unprognostic (5.82e-2)" "unprognostic (1.21e-2)" "unprognostic (4.49e-2)" "unprognostic (7.06e-3)" "unprognostic (1.13e-1)" "unprognostic (8.25e-2)" "unprognostic (1.71e-1)" 11.2 15.0 7.5 9.3 7.7 11.8 15.6 10.5 9.3 15.2 10.5 16.2 12.6 13.0 16.8 12.4 12.2 9.5 11.8 7.4 7.2 12.3 29.5 10.4 10.7 7.0 7.0 15.1 20.8 12.3 14.9 13.0 7.0 18.7 18.9 10.0 18.0 12.4 11.4 13.2 13.2 12.1 6.8 12.4 14.7 9.7 7.5 12.2 17.0 9.7 10.9 12.7 13.1 9.4 8.3 7.4 13.9 12.6 17.9 20.4 13.2 13.5 19.1 15.4 12.8 10.8 14.9 11.3 5.9 16.2 11.4 17.7 11.6 13.7 23.3 8.9 9.3 12.7 9.2 19.2 22.1 18.8 11.7 15.4 20.3 10.3 36.1 18.6 15.2 11.0 8.3 6.8 18.7 12.9 10.5 17.6 11.4 41.5 8.7 12.1 8.1 10.6 14.4 13.4 6.9 12.5 8.7 17.1 18.2 13.1 11.7 19.3 14.4 7.4 5.7 13.9 8.7 9.4 5.4 11.7 14.2 9.4 13.5 3.5 1.9 3.6 3.4 2.2 3.6 2.2 2.6 2.9 1.4 2.3 2.9 2.7 1.7 2.5 1.3 3.4 3.0 1.7 7.5 7.7 10.5 9.3 7.4 7.2 7.0 7.0 7.0 6.8 7.5 9.4 15.8 9.6 31.4 23.2 18.9 15.8 15.2 13.1 14.2 9.7 22.0 17.9 19.7 24.3 19.8 12.9 14.6 14.2 35.5 32.5 15.6 11.6 24.1 15.0 20.1 16.7 22.2 11.4 39.3 37.9 18.8 14.3 26.0 30.8 17.1 22.4 18.9 72.8 10.8 10.1 34.7 54.5 6.1 20.9 9.0 9.0 14.0 13.3 10.6 22.5 13.2 7.6 15.5 34.2 36.9 22.7 32.8 13.5 31.3 26.6 29.4 17.3 11.7 11.2 6.6 12.8 11.7 12.7 8.9 17.7 16.1 32.8 21.2 21.7 24.4 37.3 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COLEC12 "CL-P1, SCARA4, SRCL" ENSG00000158270 "Collectin subfamily member 12" Q5KU26 18 316737-500722 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 31.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 104.4;Cytotrophoblasts: 149.0;Fibroblasts: 79.6;Hofbauer cells: 155.9;Microglial cells: 245.4;Muller glia cells: 74.5;Syncytiotrophoblasts: 111.2" "Cancer enhanced" "Detected in all" "prostate cancer: 14.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 24.3;BJ: 12.1;HSkMC: 20.0;U-2197: 31.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA047917, HPA071056" Enhanced Approved "Golgi apparatus,Vesicles,Cell Junctions" NA NA 580000 "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Vesicles" "Cell Junctions" "HPA047917: AB_2680208, HPA071056: AB_2686338" "unprognostic (8.67e-2)" "unprognostic (2.23e-1)" "unprognostic (1.51e-2)" "unprognostic (3.60e-2)" "unprognostic (6.94e-2)" "unprognostic (1.09e-2)" "unprognostic (1.14e-4)" "unprognostic (2.21e-1)" "unprognostic (1.21e-1)" "unprognostic (4.86e-2)" "unprognostic (1.32e-2)" "unprognostic (1.53e-1)" "unprognostic (2.61e-1)" "unprognostic (2.24e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (3.01e-3)" 12.4 1.7 5.1 2.4 4.8 0.2 5.5 4.7 5.7 31.6 9.7 5.5 1.5 9.0 1.0 2.0 6.5 4.4 6.6 4.6 7.2 2.4 0.3 11.4 2.0 7.7 6.5 2.0 1.1 0.9 0.9 20.0 5.2 4.0 2.4 5.3 4.1 1.4 3.1 3.6 3.5 5.1 4.3 0.3 3.4 1.4 6.5 1.3 5.2 2.0 2.5 8.1 4.0 5.5 0.0 0.0 2.1 0.0 2.3 24.3 0.8 12.1 4.2 1.7 3.1 0.0 0.0 0.0 0.1 2.0 0.1 0.0 0.3 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.1 0.0 0.0 20.0 0.0 1.0 0.0 0.7 4.7 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.7 0.0 6.5 0.0 0.0 0.1 0.3 0.0 0.1 0.0 1.9 0.1 0.0 0.0 2.8 0.4 31.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.1 0.1 0.0 0.0 5.1 4.8 4.7 5.7 4.6 7.2 7.7 6.5 5.2 4.3 6.5 5.5 6.8 3.2 104.4 34.3 2.1 4.1 3.2 0.0 1.2 6.4 2.6 1.7 4.0 2.8 10.7 3.7 10.4 149.0 1.4 0.3 0.0 0.2 11.1 0.5 3.9 15.8 15.7 2.7 0.5 0.0 5.3 79.6 0.0 0.8 13.9 1.2 5.7 0.4 155.9 6.7 1.4 1.0 0.0 4.9 8.9 31.4 61.5 32.1 1.8 245.4 16.2 74.5 3.1 2.0 10.4 0.3 0.6 7.2 1.2 6.5 1.4 0.2 1.7 12.4 0.0 13.2 21.6 1.3 2.5 1.8 3.8 111.2 4.8 11.6 0.8 1.3 COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 45.1;Inhibitory neurons: 46.3;Late spermatids: 16.6;NK-cells: 15.5;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 60.9" "Lineage enriched" "Detected in many" 34 "T-cells: 60.9" "Group enriched" "Detected in some" 6 "BEWO: 11.5;HDLM-2: 3.8;U-937: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" 2.5 2.3 3.1 0.7 3.2 0.8 2.2 3.9 4.6 4.6 11.9 3.7 1.0 3.4 1.6 0.9 8.8 1.1 17.9 3.7 2.7 2.9 3.4 2.5 3.9 4.8 3.2 3.6 1.7 3.6 5.7 0.3 2.8 4.6 0.5 0.6 1.5 0.8 10.8 1.6 2.6 0.7 2.6 7.2 2.4 5.0 2.3 2.6 2.6 5.1 3.0 2.2 2.4 2.9 0.1 0.0 0.7 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.8 0.4 0.2 0.5 0.0 0.0 0.1 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.5 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.2 0.1 0.8 0.4 0.0 0.0 5.2 0.1 0.0 0.6 0.0 9.9 0.0 60.9 0.0 5.3 7.4 0.0 0.0 0.5 0.6 0.0 1.8 0.0 0.4 0.3 3.5 3.1 3.2 3.9 4.6 3.7 2.7 4.8 3.2 2.8 2.6 2.3 2.9 0.6 0.0 0.6 17.3 0.5 0.3 0.2 0.1 0.0 0.3 0.4 0.6 0.7 0.0 1.4 0.0 0.0 0.3 7.7 0.0 0.0 0.1 4.1 6.5 1.4 0.4 1.2 0.4 45.1 0.0 0.2 0.6 1.1 0.8 0.0 3.3 1.8 0.8 0.2 6.7 46.3 0.2 2.0 0.6 0.0 16.6 1.8 0.4 0.0 7.5 0.4 0.3 15.5 18.1 18.3 0.2 0.1 4.5 2.0 0.2 0.0 0.2 4.3 0.7 0.0 0.5 0.7 1.5 0.5 0.0 0.1 2.3 4.1 1.4 0.3 0.1 COMMD4 FLJ20452 ENSG00000140365 "COMM domain containing 4" Q9H0A8 15 75336020-75343224 "Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039935, HPA066957" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Vesicles, Plasma membrane" "HPA039935: , HPA066957: AB_2685754" "unprognostic (7.77e-2)" "unprognostic (3.07e-3)" "unprognostic (1.03e-1)" "unprognostic (6.57e-3)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (1.49e-1)" "unprognostic (2.60e-1)" "unprognostic (9.11e-2)" "unprognostic (1.78e-3)" "unprognostic (2.01e-1)" "unprognostic (2.65e-1)" "unprognostic (1.39e-3)" "unprognostic (2.51e-1)" "unprognostic (2.27e-1)" "unprognostic (1.96e-1)" "unprognostic (5.07e-2)" 36.2 72.3 38.8 33.5 39.4 52.9 36.8 40.5 50.4 31.1 43.7 41.6 48.3 30.3 30.2 39.9 34.6 37.3 38.9 36.9 39.7 54.6 51.0 34.6 44.7 39.5 38.1 24.4 33.8 48.9 33.9 31.2 38.6 34.2 33.8 13.4 43.4 34.0 30.3 35.0 42.2 24.7 40.8 41.3 42.5 81.2 42.4 53.3 38.8 15.3 36.7 33.6 31.8 42.0 138.2 222.5 97.5 124.8 42.3 64.9 98.5 98.8 106.2 191.2 196.6 133.8 184.0 88.8 100.2 79.5 168.8 144.8 175.2 116.5 82.7 70.1 242.4 104.8 169.8 151.0 76.4 79.4 111.0 74.3 63.6 116.2 21.9 48.4 96.5 103.6 108.2 128.1 147.1 179.7 71.0 117.4 140.9 75.2 127.9 127.5 137.4 127.8 98.6 127.8 79.2 114.8 131.2 105.1 169.8 63.8 164.7 160.9 78.6 135.3 119.2 125.8 184.8 93.4 218.7 101.4 138.9 181.9 125.4 27.0 44.1 40.7 84.7 61.8 52.8 47.5 51.7 63.2 50.0 46.4 31.9 47.4 9.5 76.8 55.6 70.6 87.6 39.4 38.8 39.4 40.5 50.4 36.9 39.7 39.5 38.1 38.6 40.8 42.4 42.0 43.7 28.9 52.4 15.0 26.2 27.0 44.8 58.5 28.5 40.7 44.3 50.3 18.7 38.6 46.2 35.0 31.3 80.9 34.8 59.6 58.7 72.6 12.2 37.1 44.9 42.7 30.5 60.8 9.0 78.7 107.0 43.4 33.1 45.7 41.8 91.1 37.5 41.9 127.5 16.8 8.8 72.8 44.7 35.8 27.0 17.6 49.0 41.3 37.4 11.2 28.5 78.1 53.5 7.1 17.6 72.4 61.7 34.3 43.0 26.6 71.2 98.1 39.8 49.4 46.0 36.1 59.3 152.9 63.5 34.3 30.7 50.8 32.2 53.4 58.7 48.7 COMTD1 FLJ23841 ENSG00000165644 "Catechol-O-methyltransferase domain containing 1" Q86VU5 10 75233641-75236030 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 128.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 334.8;Exocrine glandular cells: 249.5;Paneth cells: 272.5;Proximal enterocytes: 435.9;Squamous epithelial cells: 285.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEK 293: 30.2;PC-3: 38.3;RPMI-8226: 24.5;U-266/70: 21.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042165 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 29: Non-specific - Vesicular transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA042165: AB_10794042" "unprognostic (2.53e-2)" "unprognostic (1.23e-1)" "unprognostic (1.49e-1)" "unprognostic (9.07e-2)" "unprognostic (2.44e-1)" "unprognostic (1.36e-1)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.23e-2)" "unprognostic (8.08e-3)" "unprognostic (9.35e-2)" "unprognostic (6.74e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.33e-1)" "unprognostic (1.73e-1)" "unprognostic (1.12e-1)" "unprognostic (2.35e-1)" 11.0 17.9 1.1 1.0 1.5 1.5 9.8 1.2 1.8 18.3 5.8 23.3 7.4 7.5 0.4 70.6 7.2 0.4 33.5 1.3 1.7 29.1 37.5 11.7 0.6 1.7 2.0 8.0 128.6 3.4 17.1 0.9 1.7 11.8 1.0 1.1 23.9 1.0 28.2 25.3 25.2 0.5 1.1 12.4 27.8 3.4 1.6 0.5 18.5 0.7 0.7 8.3 29.0 0.9 6.9 2.2 0.5 1.3 0.1 0.7 19.0 2.1 1.0 0.3 0.6 1.6 6.0 20.0 3.5 0.4 1.1 9.0 0.9 1.9 0.1 3.2 30.2 0.8 4.8 3.3 1.1 3.5 3.3 0.6 3.2 0.1 2.9 1.3 0.3 3.6 7.8 4.7 0.1 6.2 5.3 11.0 1.2 5.1 38.3 10.6 1.3 24.5 1.8 0.6 8.4 2.3 2.4 16.0 4.8 0.5 8.9 0.5 1.4 0.6 5.9 1.2 2.1 21.5 4.5 9.8 0.7 3.4 0.6 0.0 7.1 3.9 10.6 10.0 11.6 7.1 10.6 11.0 8.5 5.6 3.5 6.1 1.4 7.3 9.4 15.3 8.9 6.8 1.1 1.5 1.2 1.8 1.3 1.7 1.7 2.0 1.7 1.1 1.6 0.9 23.6 19.2 11.5 1.6 18.2 29.4 40.5 54.1 133.1 6.0 29.3 37.1 31.1 57.2 33.8 53.3 10.4 33.4 30.8 334.8 144.8 162.8 1.6 10.5 7.7 13.5 40.2 16.0 3.4 249.5 79.1 13.4 148.8 33.4 12.7 10.3 25.4 84.0 35.1 1.7 3.9 206.0 42.7 24.2 21.3 3.5 9.6 21.8 37.4 6.5 31.8 10.7 24.7 1.5 0.5 109.2 272.5 7.2 50.8 38.7 435.9 140.3 11.3 34.5 32.9 6.2 25.6 2.6 3.4 285.3 38.2 30.4 29.2 10.7 143.8 56.7 COPRS "C17orf79, COPR5, HSA272196, TTP1" ENSG00000172301 "Coordinator of PRMT5 and differentiation stimulator" Q9NQ92 17 31851871-31859291 "Predicted intracellular proteins" "Myogenesis, Transcription, Transcription regulation" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 253.2;Late spermatids: 288.9;Spermatocytes: 575.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052552 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA052552: AB_2681868" "unprognostic (1.65e-2)" "unprognostic (4.88e-2)" "unprognostic (2.46e-1)" "unprognostic (4.01e-3)" "unprognostic (3.12e-2)" "unprognostic (1.12e-2)" "prognostic unfavorable (3.69e-4)" "unprognostic (6.88e-2)" "unprognostic (3.10e-1)" "unprognostic (4.44e-2)" "unprognostic (5.28e-3)" "unprognostic (1.01e-2)" "unprognostic (1.19e-3)" "unprognostic (1.02e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (3.11e-2)" 51.1 46.5 127.4 20.1 130.0 14.2 49.8 124.6 172.8 42.8 129.5 99.0 16.0 43.4 117.6 26.4 51.7 32.0 66.1 128.7 136.2 55.8 68.1 33.9 21.0 123.6 126.7 51.7 41.9 49.0 67.4 19.7 128.8 60.2 27.4 56.0 35.4 46.3 53.5 30.3 31.1 44.4 123.3 25.1 51.6 241.4 131.2 13.2 63.2 53.3 27.8 57.1 33.3 124.1 101.5 132.9 64.4 66.6 104.3 99.5 45.2 109.7 140.3 125.8 127.8 83.4 27.0 53.0 58.8 135.1 245.0 58.5 116.0 67.6 142.3 18.7 153.8 15.4 79.7 99.5 105.5 53.2 43.4 64.2 87.4 169.3 92.4 135.7 68.6 75.2 75.0 46.9 139.6 89.9 79.6 170.7 49.1 65.2 62.8 61.8 120.8 104.4 74.5 62.8 58.4 44.2 65.9 32.6 107.1 56.1 104.4 57.9 37.0 327.8 85.9 116.6 156.3 76.2 77.2 58.3 170.8 50.1 44.9 1.8 2.0 0.0 0.6 2.0 1.6 1.9 0.5 0.1 2.6 3.6 0.3 0.3 0.6 0.0 0.9 1.0 0.8 0.3 127.4 130.0 124.6 172.8 128.7 136.2 123.6 126.7 128.8 123.3 131.2 124.1 54.2 22.4 8.3 13.7 20.9 34.4 69.0 15.3 29.6 43.1 79.2 88.4 78.9 68.6 13.4 86.5 10.4 31.9 10.7 12.1 225.0 99.6 253.2 142.2 38.5 53.5 19.7 18.7 14.6 80.8 54.9 65.7 14.3 40.5 3.8 39.9 62.4 95.4 87.6 26.9 14.8 15.9 40.7 30.3 34.7 288.9 62.4 36.5 58.7 7.5 47.9 136.3 9.2 3.5 9.2 70.7 8.4 65.1 27.4 127.4 6.4 212.0 55.8 43.0 19.7 46.9 63.5 575.6 63.8 21.4 31.7 27.4 11.2 49.6 21.3 39.6 COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" 10.2 13.6 10.7 7.0 11.2 4.8 13.4 10.9 11.6 10.8 12.5 14.1 12.4 15.6 12.3 12.4 15.5 10.7 23.4 11.0 10.8 14.1 12.3 10.0 8.3 10.6 11.3 20.0 10.3 24.4 9.7 10.0 11.1 17.7 13.2 14.0 10.4 14.7 45.8 7.9 11.8 11.6 10.4 10.0 12.8 20.9 11.3 10.3 16.2 44.9 8.4 10.3 8.8 13.1 23.5 24.8 21.1 12.4 11.6 12.2 17.7 13.5 11.0 18.0 18.5 15.9 19.1 17.8 63.9 10.4 19.4 24.5 29.6 16.9 13.0 15.2 29.9 9.5 22.8 49.3 14.4 22.9 20.1 10.3 14.6 16.8 12.2 14.8 14.8 20.9 26.4 16.2 12.9 42.4 24.0 18.4 16.1 9.1 13.1 29.0 23.3 22.8 15.7 15.5 30.4 17.4 12.6 27.4 16.2 10.2 25.2 30.7 16.3 19.0 10.9 14.1 19.7 15.0 26.2 19.7 20.4 13.1 12.5 40.4 11.4 17.8 9.9 10.6 9.4 16.3 8.9 8.7 12.6 15.3 12.2 10.8 126.5 12.9 12.3 15.6 6.2 5.6 10.7 11.2 10.9 11.6 11.0 10.8 10.6 11.3 11.1 10.4 11.3 13.1 13.3 16.0 12.6 6.2 35.5 11.0 26.3 20.9 13.6 31.2 18.3 21.1 21.8 31.5 14.9 16.5 39.6 21.2 28.7 38.1 45.0 25.2 14.8 23.7 16.2 16.1 24.0 4.8 6.0 18.0 17.9 14.9 32.1 23.2 25.4 31.1 20.7 11.1 23.3 20.2 8.8 39.0 30.5 29.4 12.9 8.5 18.6 18.8 10.6 4.7 11.6 39.5 8.2 5.0 9.4 13.2 30.4 13.9 11.6 17.8 71.5 23.7 24.4 53.9 19.7 20.0 20.2 81.3 53.1 12.8 12.4 32.2 23.9 38.2 39.8 24.0 CORIN "ATC2, CRN, Lrp4, PRSC, TMPRSS10" ENSG00000145244 "Corin, serine peptidase" Q9Y5Q5 4 47593999-47838106 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "heart muscle: 56.9" "Cell type enriched" "Detected in some" 6 "Cardiomyocytes: 69.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "ASC TERT1: 44.0" "Region enhanced" "Detected in some" "basal ganglia: 2.6" "Low region specificity" "Detected in some" HPA070941 Approved "Nuclear bodies,Plasma membrane,Actin filaments" "Intracellular and membrane" Yes No "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear bodies, Actin filaments" "HPA070941: AB_2686324" "unprognostic (1.05e-1)" "unprognostic (2.52e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (2.10e-1)" "unprognostic (3.18e-1)" "unprognostic (3.58e-4)" "unprognostic (3.19e-1)" "unprognostic (3.67e-2)" "unprognostic (8.22e-2)" "unprognostic (9.78e-2)" "unprognostic (6.53e-2)" "unprognostic (1.18e-1)" "unprognostic (2.86e-2)" "unprognostic (5.18e-2)" "unprognostic (7.22e-2)" "unprognostic (1.33e-2)" 0.4 0.1 0.1 0.1 0.1 0.0 1.0 0.1 0.2 2.1 0.6 0.3 0.1 4.5 0.6 0.9 1.4 4.5 56.9 0.0 0.3 1.0 0.1 1.9 0.0 0.7 0.6 0.5 0.2 1.1 1.9 0.4 0.1 2.3 0.0 0.3 0.4 6.1 0.1 7.5 0.3 0.7 0.1 1.1 0.5 2.5 0.3 0.1 0.1 0.1 0.1 1.2 3.9 0.1 0.0 0.0 0.1 0.3 10.3 44.0 0.0 2.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 2.1 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.9 1.4 0.0 0.3 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.3 0.7 0.6 0.1 0.1 0.3 0.1 0.3 0.0 7.5 1.0 0.0 3.8 0.3 0.0 0.0 1.0 8.3 0.3 69.4 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.1 1.3 1.0 0.0 0.0 6.5 0.0 0.0 9.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 10.8 0.0 0.0 0.6 5.5 2.0 4.7 0.1 5.4 1.0 0.0 0.7 0.0 2.0 3.9 0.0 0.0 2.6 0.0 0.6 0.0 0.2 0.0 0.3 0.0 0.3 2.3 4.6 4.4 0.1 2.7 0.0 0.6 0.1 0.0 0.3 CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 301.4;Paneth cells: 324.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 221.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 51: Monocytes - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" 54.4 56.4 20.2 29.7 23.8 20.3 53.4 23.4 27.0 55.7 21.1 70.2 62.9 72.8 14.6 80.2 54.2 44.1 26.1 19.4 22.7 48.2 47.2 53.7 41.9 28.0 23.6 42.7 52.5 24.6 35.1 31.2 25.1 71.0 34.5 6.6 73.2 39.6 13.0 42.4 62.3 36.7 24.2 66.0 77.1 13.9 25.1 21.1 55.8 9.9 18.4 58.3 53.5 26.3 80.9 81.4 37.5 76.0 94.1 81.3 56.6 58.5 118.0 94.2 70.8 134.1 116.0 6.4 111.3 80.8 95.8 67.9 41.9 74.9 16.8 19.4 40.7 54.9 47.3 57.9 148.1 2.3 120.8 110.6 66.3 80.1 37.2 59.7 120.7 49.4 42.7 9.2 54.2 238.4 14.4 11.2 47.7 198.2 73.4 11.2 41.0 14.9 62.6 104.3 40.7 50.8 52.4 139.6 181.6 26.0 178.5 63.0 92.2 63.4 47.4 87.4 35.2 1.6 3.3 14.6 103.4 8.2 66.4 57.3 102.8 8.0 10.9 212.9 8.3 20.0 37.6 14.6 79.0 11.0 21.2 11.4 47.8 11.9 221.8 60.8 55.2 57.8 20.2 23.8 23.4 27.0 19.4 22.7 28.0 23.6 25.1 24.2 25.1 26.3 58.7 3.2 2.2 4.6 53.4 27.9 60.1 90.8 40.9 13.0 53.8 39.0 1.6 50.1 66.4 47.8 8.4 87.8 39.2 301.4 60.7 111.4 8.9 43.6 32.9 52.0 99.0 19.8 1.8 105.0 229.8 35.8 111.1 64.8 28.0 46.7 47.8 22.4 251.8 15.2 2.4 188.6 81.4 138.6 66.4 5.0 39.4 96.3 71.2 10.3 195.3 30.0 41.2 4.5 6.8 136.9 324.9 34.6 64.3 55.6 263.5 84.0 41.2 14.6 52.6 22.1 55.1 8.1 6.6 47.6 31.0 150.5 100.3 54.8 128.0 74.5 CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.2;Proximal enterocytes: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Cell line enhanced" "Detected in many" "BEWO: 66.6;OE19: 56.4;SK-BR-3: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" 1.9 1.7 1.9 4.9 1.5 14.8 4.7 4.9 3.2 6.1 0.0 17.5 34.3 1.6 0.7 15.2 4.7 18.2 0.3 1.2 2.9 1.1 3.3 7.4 2.9 3.7 3.4 0.3 0.4 2.5 4.0 2.1 4.9 14.3 12.9 1.2 6.1 1.4 0.3 9.3 35.1 2.2 0.8 3.0 11.1 9.2 4.5 5.7 1.2 0.3 5.9 12.8 7.7 1.8 8.4 2.9 0.6 2.0 1.2 1.3 66.6 0.6 0.7 2.1 3.2 19.1 1.4 0.1 9.4 1.2 3.2 23.1 7.7 12.7 1.3 6.9 1.8 0.2 11.6 17.1 2.7 7.9 0.7 0.4 15.4 1.0 18.6 0.7 0.7 10.0 6.8 3.8 0.3 6.3 1.5 7.8 8.6 56.4 2.2 6.1 0.1 0.2 1.3 23.5 1.7 2.4 4.4 45.3 1.6 15.0 5.3 12.8 0.6 0.2 9.7 0.2 2.4 0.7 4.0 0.7 0.5 2.5 2.8 11.2 1.4 11.4 2.4 2.9 5.2 0.6 3.9 3.7 0.5 0.5 2.5 3.3 1.0 1.7 7.8 0.7 11.9 1.5 1.9 1.5 4.9 3.2 1.2 2.9 3.7 3.4 4.9 0.8 4.5 1.8 2.8 12.8 27.8 0.7 3.1 6.6 18.9 47.2 14.8 2.1 8.5 4.3 1.9 28.6 46.4 0.0 4.2 10.5 2.1 76.2 0.0 4.5 2.6 15.6 11.6 6.0 7.2 0.8 11.6 5.1 42.2 2.2 36.2 19.9 0.0 38.1 0.7 3.8 6.0 1.7 10.5 15.7 20.3 12.0 2.6 3.9 0.0 10.6 0.0 1.0 1.8 0.7 2.1 0.5 0.8 22.6 19.7 0.4 1.4 15.7 93.0 1.7 35.8 1.7 0.0 1.5 3.7 0.5 3.3 29.4 9.9 15.9 10.7 0.2 36.3 30.4 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 COX6B2 "COXVIB2, CT59, FLJ32865" ENSG00000160471 "Cytochrome c oxidase subunit 6B2" Q6YFQ2 19 55349306-55354719 "Metabolic proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 90.5" "Cell type enhanced" "Detected in many" "Early spermatids: 36.0;Late spermatids: 27.4;Respiratory ciliated cells: 12.6;Spermatocytes: 61.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 6 "CAPAN-2: 24.9;SCLC-21H: 10.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA035014 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA035014: AB_10601261" "unprognostic (7.43e-3)" "unprognostic (8.72e-2)" "unprognostic (1.42e-1)" "unprognostic (5.75e-2)" "unprognostic (2.59e-2)" "unprognostic (9.23e-3)" "unprognostic (1.88e-2)" "unprognostic (6.45e-3)" "unprognostic (1.02e-1)" "unprognostic (6.82e-2)" "prognostic unfavorable (9.70e-5)" "unprognostic (8.11e-2)" "unprognostic (1.81e-6)" "unprognostic (9.91e-2)" "unprognostic (1.47e-1)" "unprognostic (1.02e-2)" "unprognostic (2.02e-1)" 0.7 0.1 0.3 1.0 0.2 1.1 0.9 1.0 0.5 0.4 0.4 6.7 0.2 0.2 1.2 1.2 0.7 0.2 0.1 0.3 0.3 0.8 0.1 0.3 0.2 0.3 0.5 0.5 0.2 0.0 0.9 0.2 0.4 0.7 4.8 0.4 1.4 0.2 0.3 2.5 0.3 0.2 0.1 0.3 0.2 90.5 0.3 3.3 0.1 0.0 1.9 0.5 0.9 0.6 3.1 0.4 0.1 0.1 0.0 0.0 0.2 0.4 0.1 0.3 0.5 0.2 24.9 0.1 0.2 0.3 0.3 1.8 0.7 0.2 0.2 0.9 0.7 0.0 2.0 0.1 0.3 0.2 1.8 0.2 2.7 0.5 0.6 1.7 0.0 0.1 0.4 0.2 0.0 0.6 0.1 0.2 0.6 2.6 0.5 0.1 0.0 0.2 0.1 0.4 10.1 0.3 0.4 0.1 0.0 0.6 0.4 0.0 0.5 0.2 0.5 0.1 0.3 1.6 1.4 0.1 0.1 0.3 0.1 0.8 0.2 0.3 0.2 0.1 0.1 0.2 0.2 0.1 0.0 0.3 0.2 0.2 1.5 0.5 0.2 0.4 0.2 0.3 0.3 0.2 1.0 0.5 0.3 0.3 0.3 0.5 0.4 0.1 0.3 0.6 0.2 0.0 0.5 0.0 0.0 0.5 0.7 3.5 1.2 2.4 0.9 1.3 0.6 0.0 2.1 0.0 4.2 0.5 1.8 8.0 0.0 0.5 36.0 1.3 0.5 0.2 1.2 0.0 0.0 0.6 0.3 0.6 0.0 0.8 0.0 0.2 0.0 0.0 0.1 3.3 0.1 1.3 4.1 0.0 0.0 27.4 0.6 0.3 0.0 0.0 0.0 1.4 2.1 0.0 0.1 9.6 4.1 0.0 0.3 0.7 3.4 0.1 12.6 5.4 0.0 0.4 0.5 61.1 1.7 0.3 0.4 0.4 0.6 0.1 6.5 2.3 CPEB3 KIAA0940 ENSG00000107864 "Cytoplasmic polyadenylation element binding protein 3" Q8NE35 10 92046692-92291078 "Predicted intracellular proteins" "Translation regulation" "Activator, Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 32.2" "Cell type enhanced" "Detected in many" "Astrocytes: 176.0;Early spermatids: 226.2;Excitatory neurons: 233.7;Inhibitory neurons: 286.9;Late spermatids: 408.9;Oligodendrocyte precursor cells: 148.8;Oligodendrocytes: 128.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 2.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 12.1;U-266/70: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070942 Approved "Nucleoplasm,Plasma membrane,Midbody,Cytosol" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Nucleoplasm, Plasma membrane, Midbody" "HPA070942: " "unprognostic (4.90e-2)" "unprognostic (2.12e-2)" "unprognostic (3.00e-1)" "unprognostic (5.66e-2)" "unprognostic (1.92e-1)" "unprognostic (2.95e-5)" "prognostic favorable (5.06e-5)" "unprognostic (4.09e-4)" "unprognostic (2.73e-1)" "unprognostic (2.40e-1)" "unprognostic (1.47e-2)" "unprognostic (2.42e-2)" "prognostic favorable (3.84e-9)" "unprognostic (3.33e-2)" "unprognostic (7.42e-2)" "unprognostic (1.36e-2)" "unprognostic (1.40e-1)" 1.9 3.9 6.1 1.8 7.2 1.7 3.2 6.2 17.3 2.5 2.1 2.3 3.1 1.9 4.5 4.6 1.8 2.0 5.1 6.4 4.3 4.6 32.2 2.2 1.9 10.4 5.6 3.5 3.5 3.2 4.0 1.6 11.0 4.2 2.6 7.1 7.5 2.4 19.7 4.0 3.0 2.0 1.4 2.6 2.8 12.9 4.4 1.5 6.5 9.5 2.1 1.9 3.1 7.0 0.9 0.2 0.3 1.9 0.5 0.5 0.7 0.8 0.6 1.2 0.9 0.6 1.9 1.1 1.0 0.3 0.5 2.5 0.9 0.6 0.7 1.1 0.9 1.4 1.3 0.8 1.4 0.6 1.4 0.4 1.5 0.6 2.4 1.0 1.1 1.3 0.9 12.1 0.5 0.7 0.9 0.8 0.2 1.3 0.9 1.1 1.6 2.1 1.2 0.4 1.4 0.5 0.8 2.2 1.6 1.0 2.7 1.6 0.8 0.6 0.6 0.4 0.7 6.3 1.7 1.1 0.3 2.2 0.1 2.6 0.4 0.8 0.2 0.5 0.2 0.7 0.1 0.3 0.3 0.1 0.1 0.1 0.5 0.2 0.6 0.2 0.1 0.2 6.1 7.2 6.2 17.3 6.4 4.3 10.4 5.6 11.0 1.4 4.4 7.0 6.1 6.4 7.0 176.0 6.2 8.8 4.0 4.0 7.4 26.0 20.5 10.7 25.3 5.7 4.4 12.9 50.1 2.1 3.0 11.3 5.9 3.2 226.2 9.0 3.0 7.1 19.8 3.6 233.7 2.6 1.6 5.5 4.1 10.8 3.8 4.1 12.5 75.2 4.8 30.3 286.9 9.9 8.2 23.9 3.4 408.9 5.9 10.3 5.4 87.1 8.9 3.2 4.1 148.8 128.6 3.2 4.0 7.9 4.2 10.7 10.1 5.0 8.7 24.7 0.0 4.4 4.1 13.2 7.2 22.0 13.9 1.2 3.3 3.4 5.9 6.5 CPNE9 KIAA4217 ENSG00000144550 "Copine family member 9" Q8IYJ1 3 9703826-9729908 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 69.2" "Cell type enhanced" "Detected in some" "Early spermatids: 12.9;Excitatory neurons: 28.2;Inhibitory neurons: 8.0;Late spermatids: 61.3" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enhanced" "Detected in single" "monocytes: 1.0" "Cell line enhanced" "Detected in some" "Daudi: 2.3;U-937: 2.0" "Low region specificity" "Detected in all" HPA060813 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA060813: " "unprognostic (2.96e-1)" "unprognostic (4.75e-2)" "unprognostic (1.34e-1)" "unprognostic (5.04e-3)" "unprognostic (1.10e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-4)" "unprognostic (2.67e-2)" "unprognostic (5.44e-4)" "unprognostic (1.47e-2)" "unprognostic (8.59e-2)" "unprognostic (3.45e-1)" "unprognostic (7.48e-2)" 0.1 2.1 10.9 0.2 7.1 1.2 0.1 12.1 23.6 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.1 0.1 0.1 5.8 19.6 0.2 0.0 0.3 0.2 69.2 19.8 0.1 0.1 0.1 5.3 0.1 65.0 0.1 0.1 1.1 0.1 0.2 0.0 1.7 0.3 0.2 4.2 0.2 0.3 1.3 39.6 0.1 0.1 0.0 0.1 0.1 0.1 12.9 0.0 0.3 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.6 0.5 0.0 0.0 0.2 0.4 0.7 0.9 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.4 0.3 2.0 0.1 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 10.9 7.1 12.1 23.6 5.8 19.6 69.2 19.8 65.0 4.2 39.6 12.9 0.1 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.6 0.8 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.9 0.1 0.1 0.1 0.0 0.0 28.2 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.4 0.0 1.9 0.0 8.0 0.0 0.0 0.8 0.3 61.3 0.0 0.8 0.0 3.7 0.0 0.7 0.0 2.0 2.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.9 0.7 0.2 0.4 0.0 0.1 0.0 0.1 0.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 105.2;monocytes: 127.4;Syncytiotrophoblasts: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 674.2" "Group enriched" "Detected in all" 28 "dendritic cells: 168.5;granulocytes: 674.2;monocytes: 320.8" "Cell line enhanced" "Detected in many" "Hep G2: 144.2;HMC-1: 129.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 12.5 9.4 9.1 19.3 14.1 14.0 8.2 13.0 11.4 11.0 7.3 13.3 21.3 7.9 5.1 25.2 7.1 11.2 10.1 8.3 13.3 33.7 34.4 13.7 11.7 14.0 13.1 7.6 4.8 3.9 4.1 18.5 14.4 11.1 14.8 3.7 13.1 8.6 8.2 6.5 21.4 12.9 11.3 29.8 8.7 15.5 12.2 9.2 13.2 9.6 16.6 11.5 8.8 17.3 5.0 29.7 3.3 7.7 12.0 25.3 0.5 54.1 14.5 28.4 23.1 14.5 15.2 7.3 54.6 39.6 12.5 0.4 0.0 13.5 29.3 17.0 8.2 62.5 4.2 144.2 7.4 0.1 129.9 25.4 3.0 2.5 20.2 0.1 43.1 9.9 22.1 4.3 70.4 6.3 5.6 29.1 8.7 2.4 4.2 11.9 18.8 15.6 43.0 9.4 15.3 10.0 0.2 48.5 20.0 15.3 10.5 13.7 65.0 40.6 8.5 0.2 0.1 0.1 1.0 11.6 9.1 31.7 8.8 57.1 224.0 146.1 9.1 320.0 7.8 10.8 7.6 10.0 168.5 8.4 2.4 5.7 674.2 13.5 320.8 41.1 13.8 129.7 9.1 14.1 13.0 11.4 8.3 13.3 14.0 13.1 14.4 11.3 12.2 17.3 12.3 9.6 16.7 8.1 8.7 4.6 3.4 4.9 4.6 3.3 4.7 4.7 10.7 10.0 11.4 14.7 8.4 105.2 18.5 9.2 60.7 43.1 3.6 5.3 13.5 16.7 6.0 31.7 13.1 12.8 15.6 12.6 4.1 9.4 54.4 8.1 7.5 45.8 47.1 10.1 10.2 9.3 6.1 80.3 30.7 4.1 15.5 59.0 7.2 30.0 127.4 13.5 8.2 21.1 70.9 31.9 18.3 24.0 4.4 3.2 40.6 66.0 13.4 6.1 26.3 17.6 11.9 2.5 9.9 14.8 4.5 131.9 8.3 13.6 15.4 1.7 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CRB3 MGC17303 ENSG00000130545 "Crumbs cell polarity complex component 3" Q9BUF7 19 6463777-6467221 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 54.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 160.9;Pancreatic endocrine cells: 149.9;Paneth cells: 177.3;Suprabasal keratinocytes: 139.5;Urothelial cells: 243.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 9.2" "Group enriched" "Detected in many" 20 "B-cells: 3.1;T-cells: 9.2" "Cell line enhanced" "Detected in some" "A-431: 57.9;BEWO: 35.1;CACO-2: 38.1;HaCaT: 36.9;hTCEpi: 27.8;OE19: 33.1;SK-BR-3: 29.5;T-47d: 25.8" "Low region specificity" "Detected in many" HPA013835 Enhanced Supported "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA013835: AB_1847214" "unprognostic (3.25e-1)" "unprognostic (4.41e-2)" "unprognostic (9.69e-2)" "prognostic favorable (4.54e-4)" "unprognostic (1.24e-1)" "unprognostic (1.95e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-2)" "unprognostic (1.86e-1)" "unprognostic (2.57e-2)" "unprognostic (4.98e-2)" "unprognostic (1.11e-1)" "prognostic favorable (0.00e+0)" "unprognostic (8.42e-3)" "unprognostic (1.96e-1)" "unprognostic (1.12e-2)" "prognostic favorable (8.06e-5)" 0.8 0.4 0.3 4.0 0.7 0.3 5.1 1.2 0.5 9.3 6.1 26.9 36.9 2.2 4.6 54.5 8.2 8.2 0.3 0.3 0.2 34.1 32.5 19.0 0.9 0.4 0.2 0.4 44.0 20.7 15.9 3.5 0.5 9.1 10.5 0.4 24.8 8.9 0.1 41.9 30.6 0.5 0.1 0.8 31.1 0.4 0.2 0.8 16.2 0.0 5.4 6.4 17.6 0.5 57.9 7.0 0.0 0.2 0.0 0.1 35.1 0.0 0.0 0.0 0.0 38.1 23.8 0.3 22.1 0.0 0.3 36.9 0.4 12.5 0.0 0.0 0.4 0.1 0.2 21.5 0.0 0.1 0.1 0.0 27.8 0.0 0.0 0.0 0.1 0.5 0.1 0.5 0.0 15.1 0.2 0.4 1.3 33.1 0.0 0.0 0.0 0.7 16.5 24.0 0.0 0.1 0.2 29.5 0.1 1.7 25.8 0.2 0.0 0.1 0.4 0.2 0.1 0.7 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 1.3 3.1 4.6 2.2 0.0 1.0 9.2 3.6 0.3 0.0 0.0 0.0 3.4 1.9 0.3 0.7 1.2 0.5 0.3 0.2 0.4 0.2 0.5 0.1 0.2 0.5 0.2 35.3 38.0 0.0 2.2 72.1 64.6 81.3 21.1 0.0 43.6 19.9 0.3 71.4 64.0 31.3 0.0 28.1 0.9 160.9 46.9 113.0 0.0 43.8 4.0 1.8 16.8 3.2 0.1 101.5 9.8 2.0 34.7 58.3 1.3 0.1 0.4 31.8 2.5 0.0 0.0 60.2 63.1 1.0 6.2 0.0 0.0 1.3 7.2 0.0 2.7 0.9 0.0 0.0 0.1 149.9 177.3 0.0 3.1 94.4 86.8 44.5 36.3 0.5 0.0 0.0 4.2 1.1 0.4 45.0 139.5 56.2 3.2 0.2 52.0 243.6 CRCP "C17, CGRP-RCP, POLR3I, RCP, RCP9" ENSG00000241258 "CGRP receptor component" O75575 7 66114604-66154568 "Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006883, HPA007216" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA006883: , HPA007216: AB_1856160" "unprognostic (2.36e-2)" "unprognostic (4.43e-1)" "unprognostic (2.32e-3)" "unprognostic (1.42e-3)" "unprognostic (3.38e-2)" "unprognostic (6.26e-2)" "unprognostic (2.67e-3)" "unprognostic (8.17e-2)" "unprognostic (1.77e-3)" "unprognostic (2.59e-3)" "unprognostic (8.49e-2)" "unprognostic (9.35e-2)" "unprognostic (1.39e-3)" "unprognostic (3.87e-2)" "unprognostic (4.81e-1)" "unprognostic (3.50e-1)" "unprognostic (2.06e-1)" 13.5 15.3 10.8 13.8 11.4 37.5 17.6 12.7 14.1 14.7 11.2 18.3 16.8 14.7 11.3 20.0 17.3 13.1 17.5 11.3 13.7 16.5 26.5 14.5 16.4 11.6 12.2 16.9 20.6 21.2 11.1 13.7 14.1 17.3 19.6 14.2 16.1 15.8 14.8 16.1 14.7 18.2 11.3 17.4 17.9 8.3 13.9 15.2 20.0 13.6 16.6 16.6 14.4 12.4 44.0 26.9 19.5 26.4 27.0 33.7 19.0 29.9 31.9 43.7 33.7 43.5 34.6 40.6 35.7 29.0 37.0 32.4 26.7 35.9 46.1 26.0 27.3 23.1 19.1 20.9 19.4 47.6 32.6 27.0 30.9 38.3 71.6 27.8 23.7 23.1 49.3 28.8 30.0 35.0 36.7 37.7 39.8 58.7 33.6 38.4 30.1 37.8 27.8 40.5 46.1 60.3 34.3 95.2 29.2 22.8 73.6 24.0 27.6 63.4 33.6 36.5 56.3 35.4 70.0 54.3 35.9 36.8 51.6 25.9 12.0 20.4 17.6 11.1 17.1 14.4 15.4 14.9 9.1 13.4 14.5 17.3 20.9 10.9 17.0 12.0 16.0 12.0 10.8 11.4 12.7 14.1 11.3 13.7 11.6 12.2 14.1 11.3 13.9 12.4 24.8 28.9 32.5 12.1 30.4 13.4 22.2 13.9 24.5 29.9 19.7 19.2 25.7 12.8 23.0 16.5 22.9 12.6 47.8 15.5 35.2 21.3 4.4 27.7 30.3 18.1 16.1 12.2 19.5 24.8 11.8 20.5 27.5 29.4 34.1 22.8 9.7 25.2 12.1 30.3 20.5 15.4 8.2 13.6 9.2 4.3 18.6 17.7 16.0 12.2 20.6 23.0 22.6 12.5 17.2 29.8 10.2 22.2 26.5 26.2 10.5 17.6 32.8 25.8 6.6 27.2 18.5 24.5 16.7 20.9 14.8 11.5 27.3 28.6 14.7 32.1 CREB5 "CRE-BPA, H_GS165L15.1" ENSG00000146592 "CAMP responsive element binding protein 5" Q02930 7 28299321-28825894 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 35.0" "Cell type enhanced" "Detected in many" "Adipocytes: 165.7;Basal prostatic cells: 192.2;monocytes: 163.9;Oligodendrocyte precursor cells: 229.7;Oligodendrocytes: 734.9" "Cancer enhanced" "Detected in many" "renal cancer: 5.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 198.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 198.8" "Cell line enhanced" "Detected in many" "HL-60: 62.5;Karpas-707: 25.0;U-2 OS: 25.7;U-2197: 28.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA050020, HPA061622" Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 50: Neutrophils - Cellular senescence" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Vesicles, Plasma membrane" "HPA050020: AB_2680993, HPA061622: AB_2684569" "unprognostic (3.59e-2)" "unprognostic (3.80e-1)" "unprognostic (1.06e-1)" "unprognostic (6.46e-2)" "unprognostic (1.01e-1)" "unprognostic (4.90e-3)" "unprognostic (2.01e-3)" "unprognostic (2.87e-1)" "unprognostic (3.31e-1)" "unprognostic (1.04e-1)" "unprognostic (3.49e-1)" "unprognostic (2.67e-1)" "unprognostic (4.91e-3)" "unprognostic (6.61e-2)" "unprognostic (3.95e-1)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" 10.5 1.3 6.3 7.9 20.5 6.1 5.0 6.8 12.7 1.7 0.0 3.5 0.9 8.4 2.8 3.5 2.2 11.4 5.3 9.6 19.9 3.0 1.8 6.1 0.9 19.7 14.6 0.7 3.2 0.2 1.1 3.7 15.8 1.2 1.7 1.3 3.5 1.0 3.2 2.9 2.2 4.7 2.9 7.4 1.4 0.7 23.0 0.7 1.8 4.0 0.8 4.4 2.2 35.0 0.1 0.6 7.3 0.4 0.4 10.3 0.3 0.7 1.6 4.4 6.6 4.2 2.7 18.9 1.3 1.8 4.5 0.7 0.2 6.4 13.8 0.0 5.0 20.4 4.2 0.4 0.4 62.5 0.7 1.3 1.2 18.9 20.1 0.9 3.0 0.1 2.4 25.0 1.5 0.1 0.1 0.0 9.1 0.1 7.4 0.5 6.8 0.5 9.0 2.0 0.7 5.2 0.3 0.4 2.2 10.0 0.2 1.5 0.8 8.6 25.7 28.7 8.5 1.5 4.5 0.2 9.4 0.3 14.8 0.1 29.9 0.0 0.0 9.7 0.0 1.9 0.0 0.0 18.2 0.1 0.0 0.0 198.8 0.0 3.9 0.3 0.0 7.0 6.3 20.5 6.8 12.7 9.6 19.9 19.7 14.6 15.8 2.9 23.0 35.0 165.7 6.4 7.2 10.7 3.2 21.9 192.2 8.2 13.1 1.3 10.7 8.9 16.8 17.2 6.3 12.9 0.0 4.0 0.8 0.0 1.9 74.2 0.4 41.0 56.3 31.3 0.0 0.4 17.0 27.4 13.4 108.0 3.1 69.7 14.0 0.6 14.3 0.5 8.3 5.0 22.2 0.0 6.1 47.4 118.2 1.6 5.9 75.8 30.2 22.5 163.9 14.3 4.1 229.7 734.9 22.5 0.0 0.4 3.2 44.9 0.0 25.6 4.7 0.9 19.7 143.5 31.8 12.6 7.3 12.0 13.2 24.8 3.1 2.6 0.0 35.1 CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;choroid plexus: 21.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.0;Excitatory neurons: 8.2;Horizontal cells: 13.5;Inhibitory neurons: 4.9;Smooth muscle cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" 0.6 0.0 1.5 0.0 1.0 0.0 0.6 0.4 6.0 0.3 21.7 0.2 0.3 0.3 0.0 0.2 0.5 0.1 2.1 2.3 1.0 0.8 0.0 0.1 0.0 1.4 1.0 0.4 1.7 0.1 4.2 0.0 0.4 0.2 0.1 2.5 0.3 1.3 1.2 0.2 0.3 0.1 0.4 0.0 0.2 0.8 2.8 0.0 0.7 2.2 0.0 0.3 0.2 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.4 6.0 2.3 1.0 1.4 1.0 0.4 0.4 2.8 2.4 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 4.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRIP1 CRIP ENSG00000213145 "Cysteine rich protein 1" P50238 14 105486317-105488947 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 980.8;Endometrial ciliated cells: 1761.1;Proximal enterocytes: 2548.8;Respiratory ciliated cells: 1702.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A549: 699.8;CAPAN-2: 415.5;HaCaT: 464.1;HDLM-2: 329.5;OE19: 1305.8;T-47d: 586.0" HPA042462 Approved Approved "Nuclear speckles,Plasma membrane,Centrosome,Cytosol" NA NA 29000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Nuclear speckles, Cytosol" "Plasma membrane, Centrosome" "HPA042462: AB_10794277" "unprognostic (2.97e-3)" "unprognostic (1.27e-3)" "unprognostic (1.34e-2)" "unprognostic (1.17e-2)" "unprognostic (2.39e-1)" "unprognostic (2.93e-3)" "unprognostic (4.33e-1)" "unprognostic (3.33e-1)" "unprognostic (3.20e-2)" "unprognostic (2.60e-2)" "unprognostic (2.87e-1)" "unprognostic (9.16e-2)" "unprognostic (3.26e-3)" "unprognostic (5.10e-2)" "unprognostic (2.66e-1)" "unprognostic (7.51e-3)" "unprognostic (2.14e-1)" 265.2 21.7 19.2 61.1 19.7 29.4 180.8 20.0 36.4 147.4 20.3 133.9 121.7 108.0 206.6 118.7 118.2 28.1 262.6 18.5 20.3 109.7 17.8 254.6 83.9 26.9 29.1 49.8 18.3 21.2 41.5 28.3 24.6 49.6 55.4 0.2 135.7 87.9 44.7 301.1 312.5 42.4 24.7 94.5 94.2 14.3 21.0 79.6 182.1 50.2 135.7 113.7 98.9 20.3 0.0 699.8 4.8 0.6 12.1 8.3 66.8 1.3 0.4 9.0 0.1 21.0 415.5 228.0 2.4 191.0 2.6 464.1 0.1 0.0 0.0 329.5 0.0 17.7 294.7 116.3 1.8 0.1 0.2 3.8 0.0 23.1 0.0 0.9 0.5 64.6 0.5 0.9 0.0 3.7 8.1 1.6 7.4 1305.8 36.4 181.3 0.0 45.5 0.0 0.0 18.5 1.3 2.6 1.2 0.0 0.5 586.0 106.4 1.5 0.4 0.4 5.5 0.0 0.3 0.2 17.9 0.0 0.0 0.6 121.8 218.6 313.1 209.2 214.4 135.1 697.0 442.0 222.1 442.9 384.2 85.4 100.2 13.9 323.5 283.9 291.3 694.8 465.6 19.2 19.7 20.0 36.4 18.5 20.3 26.9 29.1 24.6 24.7 21.0 20.3 50.2 980.8 256.2 0.3 350.7 186.5 1.2 79.5 67.2 0.0 88.1 18.3 1.0 2.8 501.3 51.5 0.0 2.1 287.8 360.4 1.9 20.5 3.6 1761.1 124.5 86.4 76.5 27.3 0.0 3.1 4.3 313.3 210.0 491.9 521.5 0.1 24.7 1.3 52.2 0.0 0.0 243.1 30.5 168.0 577.3 26.2 25.1 523.7 370.0 1.9 461.4 0.2 83.4 0.0 0.1 34.2 659.2 9.4 584.3 0.7 2548.8 2.5 1702.1 0.0 223.5 8.2 448.0 1.0 11.4 29.4 251.6 1.5 524.7 0.1 190.7 3.0 CRIP2 "CRP2, ESP1" ENSG00000182809 "Cysteine rich protein 2" P52943 14 105472962-105480162 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "heart muscle: 1113.7" "Cell type enhanced" "Detected in many" "Adipocytes: 459.4;Cardiomyocytes: 863.3;Endothelial cells: 510.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 52.1;memory CD4 T-cell: 80.4;naive B-cell: 109.9;T-reg: 115.6" "Group enriched" "Detected in all" 30 "B-cells: 109.9;T-cells: 115.6" "Cell line enhanced" "Detected in many" "EFO-21: 321.9;MCF7: 306.5;SK-BR-3: 303.7;T-47d: 266.4;TIME: 259.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042664 Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA 160000 "Cluster 26: Non-specific - Mitochondria" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 38: EFO-21 - Unknown function" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoli "Nucleoplasm, Plasma membrane" "HPA042664: AB_10797017" "unprognostic (2.68e-1)" "unprognostic (6.53e-3)" "unprognostic (2.11e-3)" "unprognostic (2.19e-1)" "unprognostic (2.39e-1)" "unprognostic (2.14e-1)" "unprognostic (1.63e-2)" "unprognostic (2.56e-1)" "unprognostic (3.20e-3)" "unprognostic (9.68e-2)" "unprognostic (6.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.04e-2)" "unprognostic (6.25e-2)" "unprognostic (2.35e-2)" "unprognostic (2.39e-2)" "unprognostic (8.26e-3)" 177.6 44.7 160.4 31.3 172.0 1.5 162.5 137.7 259.5 101.6 124.2 101.9 27.0 138.1 36.4 127.3 130.0 47.9 1113.7 172.7 186.4 205.1 52.7 185.7 30.0 157.3 158.7 51.2 46.1 19.2 175.0 49.6 158.6 89.0 8.3 4.1 100.0 72.9 52.5 128.9 82.8 32.0 145.0 104.1 66.1 92.8 191.9 10.4 155.6 42.7 16.5 121.4 100.4 140.8 2.5 201.2 37.9 98.3 4.3 19.9 10.0 17.5 1.9 2.8 1.0 7.1 44.2 0.2 321.9 73.8 4.5 166.8 3.6 50.8 0.1 2.3 1.9 0.2 132.5 73.8 24.3 0.0 25.5 10.5 4.4 5.2 26.2 38.4 192.7 0.2 0.5 1.4 26.8 306.5 0.5 0.6 10.0 45.7 143.4 0.4 7.7 9.9 140.1 0.6 61.6 175.3 30.0 303.7 1.9 4.9 266.4 0.1 259.3 82.7 38.8 2.3 50.5 0.7 0.6 0.9 24.3 0.3 179.3 0.2 1.9 0.0 7.5 0.9 6.8 52.1 80.4 17.2 3.6 109.9 17.8 4.5 1.0 3.7 0.5 0.5 115.6 10.4 160.4 172.0 137.7 259.5 172.7 186.4 157.3 158.7 158.6 145.0 191.9 140.8 459.4 157.0 33.7 17.9 15.0 153.2 96.7 206.4 29.0 2.7 110.0 140.7 863.3 107.2 127.1 189.4 4.2 2.6 8.2 0.9 154.6 106.8 37.9 125.1 28.8 510.4 25.2 9.7 16.4 87.6 30.5 132.9 32.1 126.6 7.6 0.4 346.3 30.4 3.0 94.2 3.0 0.3 81.4 11.8 92.6 84.0 28.0 9.3 156.5 27.2 2.5 57.2 1.0 4.5 3.1 48.9 0.1 14.7 7.0 37.4 0.2 17.0 155.7 4.0 276.1 108.1 339.5 27.8 46.1 20.1 196.8 32.0 32.5 5.9 0.2 103.2 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CRLF3 "CREME9, CYTOR4" ENSG00000176390 "Cytokine receptor like factor 3" Q8IUI8 17 30769388-30824692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007596 Enhanced Approved "Plasma membrane,Cytosol" NA NA 210000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA007596: AB_1847241" "unprognostic (1.02e-1)" "unprognostic (9.79e-2)" "unprognostic (7.12e-2)" "unprognostic (9.65e-2)" "unprognostic (2.28e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-2)" "unprognostic (9.22e-2)" "unprognostic (1.00e-2)" "unprognostic (3.10e-2)" "unprognostic (5.81e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.31e-7)" "unprognostic (3.35e-1)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (6.51e-2)" 7.5 4.9 3.5 21.5 3.2 20.6 7.0 10.5 4.4 7.6 0.2 7.8 6.1 5.3 2.8 12.8 4.9 7.5 4.3 4.5 2.7 4.2 5.4 9.1 35.5 1.8 1.9 4.3 4.4 7.9 4.7 12.6 2.4 4.7 7.9 9.5 5.9 3.8 3.8 11.1 9.7 6.5 1.3 23.4 6.6 10.3 3.7 33.4 4.3 4.4 32.7 11.0 8.0 3.0 11.3 12.2 7.5 15.6 13.4 10.3 11.1 10.4 10.1 19.8 20.6 13.5 7.4 36.8 15.2 13.0 19.3 19.2 12.8 8.6 23.6 17.6 23.3 15.7 9.9 10.3 7.4 21.0 11.2 6.1 11.8 16.0 13.4 7.4 19.4 32.9 40.1 37.6 12.6 6.8 46.6 21.8 14.9 18.7 7.4 20.0 24.2 22.2 13.1 9.4 5.3 12.5 10.6 16.1 11.6 15.6 12.5 10.3 10.4 11.4 13.9 18.5 25.8 15.7 14.2 24.9 10.9 16.6 12.9 53.7 57.9 139.9 37.0 59.5 39.3 46.7 52.2 42.4 43.0 46.8 99.9 75.6 117.3 40.3 72.1 22.0 63.7 84.5 3.5 3.2 10.5 4.4 4.5 2.7 1.8 1.9 2.4 1.3 3.7 3.0 10.4 0.0 12.5 17.6 50.9 22.6 8.0 5.4 16.5 17.9 7.0 4.3 4.5 2.8 4.6 7.3 14.6 18.7 36.2 9.2 5.9 5.1 13.5 6.1 8.4 10.6 3.6 46.9 54.8 5.3 17.6 7.7 13.3 9.1 22.8 5.5 8.9 4.2 16.8 6.7 56.5 3.9 8.2 26.1 25.0 21.3 6.5 26.7 5.4 42.2 39.9 4.7 47.4 38.7 38.0 9.1 3.4 4.1 25.7 8.4 2.6 5.3 8.9 25.2 13.1 9.2 7.5 27.5 27.3 11.4 27.8 45.8 47.1 5.3 4.2 7.8 CROCC "ROLT, rootletin" ENSG00000058453 "Ciliary rootlet coiled-coil, rootletin" Q5TZA2 1 16740273-16972964 "Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021191, HPA021762" Enhanced Supported "Plasma membrane,Centrosome" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Centrosome" "HPA021191: AB_1856395, HPA021762: AB_1856396" "unprognostic (9.07e-3)" "unprognostic (9.03e-2)" "unprognostic (6.04e-2)" "prognostic favorable (8.34e-5)" "unprognostic (3.27e-1)" "unprognostic (1.25e-3)" "unprognostic (1.42e-3)" "prognostic favorable (7.92e-4)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (3.36e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (1.58e-1)" "unprognostic (9.83e-2)" "unprognostic (6.05e-2)" "unprognostic (1.76e-3)" 7.6 7.6 5.2 2.3 5.5 1.6 8.0 10.1 7.2 13.5 29.0 10.2 1.7 10.4 0.7 10.0 22.7 1.4 6.2 5.8 6.2 8.3 3.3 8.4 2.4 9.5 11.5 13.3 10.7 1.7 10.2 1.3 6.1 10.4 0.4 11.3 7.6 1.8 6.2 14.3 7.9 1.1 6.2 10.2 8.9 5.3 6.6 2.8 8.1 1.2 0.7 9.2 11.4 6.9 4.1 1.7 3.1 3.1 2.1 1.9 1.2 2.9 0.9 0.9 1.0 0.2 1.8 10.9 2.7 1.3 0.3 4.9 0.7 2.2 0.1 0.9 5.6 5.0 6.1 0.8 3.7 0.3 4.9 1.7 5.0 0.9 0.8 1.7 1.5 7.7 0.7 2.7 0.3 3.5 3.4 1.2 11.1 0.9 2.6 3.1 4.1 3.8 0.7 1.1 9.4 10.2 3.1 2.0 9.7 0.9 4.1 1.4 4.3 2.6 3.4 6.8 2.3 4.7 3.7 2.2 2.6 0.7 3.3 0.0 0.0 0.3 0.3 0.1 0.5 0.1 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 0.1 5.2 5.5 10.1 7.2 5.8 6.2 9.5 11.5 6.1 6.2 6.6 6.9 9.0 0.0 4.6 14.0 5.4 6.2 4.1 4.4 17.1 26.3 7.9 7.7 5.8 5.7 4.1 5.5 27.1 1.3 8.2 2.3 0.0 4.7 5.5 35.2 6.3 7.1 3.6 2.5 27.9 2.3 6.5 11.3 6.1 5.9 1.3 28.2 6.4 1.8 2.4 3.3 24.0 4.3 4.1 1.6 5.3 2.6 19.3 3.4 5.4 11.2 3.1 11.7 12.3 13.0 19.9 2.4 1.9 12.8 2.1 2.0 0.8 1.5 34.0 109.7 0.0 12.8 9.4 1.2 12.8 13.1 5.1 1.1 8.0 3.5 2.7 2.2 CRTC1 "FLJ14027, KIAA0616, MECT1, TORC1" ENSG00000105662 "CREB regulated transcription coactivator 1" Q6UUV9 19 18683678-18782333 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Biological rhythms, Host-virus interaction, Transcription, Transcription regulation" Activator "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 37.4;Horizontal cells: 43.7" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 203 "amygdala: 14.2;basal ganglia: 11.4;cerebellum: 27.1;cerebral cortex: 24.3;hippocampal formation: 24.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022035, HPA063619" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane, Cytosol" "HPA022035: AB_1847255, HPA063619: " "unprognostic (5.95e-3)" "unprognostic (2.57e-1)" "unprognostic (9.94e-2)" "unprognostic (8.62e-3)" "unprognostic (9.07e-2)" "unprognostic (1.57e-2)" "unprognostic (1.04e-1)" "unprognostic (5.57e-2)" "unprognostic (2.27e-1)" "unprognostic (6.68e-2)" "prognostic favorable (1.80e-5)" "unprognostic (3.37e-2)" "prognostic favorable (3.83e-5)" "unprognostic (6.83e-3)" "unprognostic (1.02e-1)" "unprognostic (2.51e-2)" "unprognostic (2.03e-2)" 8.8 11.3 14.2 5.2 11.4 2.1 8.2 27.1 24.3 11.3 0.0 8.9 4.0 9.3 3.4 5.2 10.3 3.2 10.5 24.5 0.0 12.8 10.4 7.9 4.1 0.0 0.0 9.4 9.8 4.7 23.7 3.9 0.0 11.6 1.5 4.4 7.3 5.1 14.4 7.4 8.5 2.5 0.0 9.6 9.9 11.3 0.0 3.6 14.4 3.6 2.2 9.7 7.4 0.0 5.2 7.9 6.7 10.7 6.3 4.5 18.6 5.4 3.6 5.3 4.8 5.1 6.6 7.1 11.6 5.2 3.9 5.5 2.1 3.5 1.3 3.1 15.1 6.0 7.8 9.3 5.5 8.3 16.3 7.8 2.9 4.4 1.3 6.8 3.1 7.2 4.8 6.3 3.0 15.2 5.7 10.0 8.8 2.7 13.1 8.7 2.9 8.1 3.2 8.0 12.1 10.7 6.0 5.8 7.0 2.2 6.6 5.2 5.4 6.0 9.1 10.8 6.4 4.4 3.6 4.6 6.9 8.6 4.6 0.3 0.6 0.4 0.4 0.2 0.3 0.5 0.5 0.6 0.7 0.7 0.5 0.3 0.2 0.3 0.4 0.8 0.4 0.4 14.2 11.4 27.1 24.3 24.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 5.3 31.0 6.9 2.7 8.9 7.8 5.7 29.1 5.8 6.1 17.7 10.0 3.5 18.4 27.1 9.7 7.9 6.8 11.7 4.6 1.1 9.6 14.0 5.6 19.2 3.6 37.4 6.0 2.7 7.5 8.6 9.8 2.5 14.7 3.9 4.7 8.8 43.7 26.7 7.1 12.2 6.0 4.0 3.2 9.3 6.3 3.6 10.3 5.5 9.1 8.2 12.1 20.2 3.5 9.6 4.9 2.0 3.0 6.1 5.0 4.8 14.7 0.0 14.2 6.6 2.9 8.8 2.4 2.0 10.4 5.1 8.3 5.2 3.6 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CRYBG3 DKFZp667G2110 ENSG00000080200 "Crystallin beta-gamma domain containing 3" Q68DQ2 3 97822011-97944984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 122.6;Bipolar cells: 123.6;Early spermatids: 121.4;Late spermatids: 131.8;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 3.6;granulocytes: 1.5;monocytes: 1.4" "Cell line enhanced" "Detected in many" "SCLC-21H: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075635 Approved "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075635: " "unprognostic (1.88e-1)" "unprognostic (7.62e-3)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (7.60e-2)" "unprognostic (2.70e-2)" "unprognostic (2.45e-2)" "unprognostic (7.10e-2)" "unprognostic (3.41e-3)" "unprognostic (6.59e-2)" "unprognostic (2.80e-2)" "unprognostic (7.86e-2)" "prognostic favorable (7.07e-4)" "unprognostic (1.78e-2)" "unprognostic (1.58e-1)" "unprognostic (1.14e-2)" "unprognostic (6.38e-3)" 10.6 2.8 5.3 5.5 12.6 0.8 7.7 9.2 8.0 8.0 3.4 7.0 3.6 6.6 2.7 8.9 5.6 5.3 6.5 5.3 10.6 4.9 3.2 5.7 3.4 15.5 10.0 3.5 5.4 3.7 1.2 10.7 16.0 5.0 7.6 7.8 6.3 4.1 7.5 12.9 4.5 6.4 11.3 4.0 5.3 14.0 10.0 2.8 26.6 9.9 4.5 7.5 4.6 17.2 16.5 6.1 3.5 4.2 11.1 11.8 6.2 5.8 5.3 4.2 6.3 0.4 5.4 0.1 1.9 10.1 6.2 10.5 7.0 4.9 8.0 20.4 3.8 4.1 2.7 2.1 5.8 6.1 1.0 7.7 4.9 5.3 5.8 6.9 8.2 1.3 0.3 3.0 7.4 0.2 2.2 0.7 3.0 4.5 5.5 0.0 12.3 2.1 6.1 10.9 39.2 3.0 12.2 4.8 3.9 2.2 4.2 6.8 10.9 8.9 6.9 5.2 7.1 5.0 0.1 3.7 9.3 3.5 5.8 1.5 1.4 0.0 0.1 0.9 0.2 0.1 0.2 0.2 1.4 0.2 0.1 0.1 0.0 0.0 1.0 3.6 0.0 0.3 5.3 12.6 9.2 8.0 5.3 10.6 15.5 10.0 16.0 11.3 10.0 17.2 122.6 32.1 19.6 48.0 4.2 5.1 7.0 3.7 23.9 123.6 13.7 9.3 37.6 1.5 16.9 18.4 6.2 4.0 13.8 6.0 1.9 8.8 121.4 32.6 48.9 52.1 12.7 2.5 37.5 13.1 11.3 38.0 18.3 22.7 0.0 68.0 15.0 5.1 6.6 13.5 23.0 8.3 2.0 17.4 3.0 131.8 8.4 18.9 8.8 37.5 22.1 29.4 1.0 10.6 128.3 13.2 8.7 4.5 12.0 7.1 2.5 2.8 21.3 9.6 39.5 29.2 18.2 49.6 9.5 24.5 6.1 2.3 3.0 14.0 5.2 7.0 CRYL1 "GDH, lambda-CRY, MGC149525, MGC149526" ENSG00000165475 "Crystallin lambda 1" Q9Y2S2 13 20403666-20525873 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 329.8;liver: 254.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 485.2;Hepatocytes: 306.1;Proximal enterocytes: 509.9;Proximal tubular cells: 1033.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040403, HPA058848" Approved Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA 690000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Nucleoli" "Golgi apparatus, Plasma membrane" "HPA040403: AB_10795632, HPA058848: " "unprognostic (1.84e-1)" "unprognostic (1.25e-1)" "unprognostic (3.25e-2)" "prognostic favorable (1.76e-5)" "unprognostic (3.10e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-3)" "unprognostic (4.75e-3)" "unprognostic (1.19e-1)" "unprognostic (4.09e-2)" "unprognostic (2.12e-2)" "unprognostic (8.80e-2)" "prognostic favorable (2.30e-9)" "unprognostic (9.00e-2)" "unprognostic (1.30e-1)" "unprognostic (2.39e-2)" "unprognostic (3.11e-1)" 33.7 31.8 69.5 15.4 81.3 11.2 27.1 75.4 78.1 33.0 65.6 62.1 190.2 30.5 51.7 24.7 26.5 30.0 30.4 65.2 79.0 329.8 254.1 19.9 19.4 76.3 71.9 19.8 46.9 31.4 38.1 16.1 76.1 32.2 49.3 20.7 41.6 36.5 17.0 16.3 131.6 22.8 77.2 23.3 45.2 4.9 71.9 18.0 35.0 20.7 16.3 20.9 23.6 89.8 8.1 6.9 6.4 42.7 31.6 36.1 5.8 11.1 20.0 4.8 3.9 2.6 7.8 0.1 20.6 15.5 10.9 1.9 5.7 9.9 4.9 19.4 4.7 14.2 0.8 55.1 18.1 4.6 12.2 21.5 6.4 3.9 22.0 17.1 51.7 20.3 1.0 5.8 12.7 29.2 12.7 7.2 0.4 68.7 10.2 6.4 3.8 1.0 40.8 16.9 4.2 5.0 6.6 3.1 51.0 3.0 21.2 18.0 50.1 5.8 2.6 14.3 7.1 7.6 1.6 0.0 11.1 7.9 24.5 5.8 50.7 3.2 23.2 59.6 18.9 20.5 30.6 22.1 60.5 23.1 23.5 22.2 1.7 15.6 50.6 6.4 37.5 43.8 69.5 81.3 75.4 78.1 65.2 79.0 76.3 71.9 76.1 77.2 71.9 89.8 29.2 6.4 10.3 57.8 17.7 10.3 15.9 29.7 6.2 6.1 22.0 11.6 10.5 35.8 25.6 77.3 12.5 22.0 10.0 138.5 485.2 26.1 3.6 32.5 8.8 29.1 9.1 6.9 54.5 31.6 11.2 29.8 34.1 27.2 25.3 8.8 50.7 306.1 71.4 1.7 35.3 89.0 32.6 91.6 34.3 4.3 26.1 51.3 37.4 13.1 19.3 112.2 9.2 33.7 114.1 43.2 219.1 24.0 14.3 23.0 509.9 1033.9 20.9 12.6 19.7 23.4 14.7 1.0 2.7 13.0 9.2 20.8 20.1 20.7 105.2 15.0 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1408.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2403.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" NA NA 100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: AB_2681767" "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 412.5 166.8 149.0 170.9 168.8 276.4 241.9 160.5 170.8 193.8 163.5 300.1 187.3 226.7 196.2 247.2 162.9 172.0 414.8 137.6 169.8 228.2 233.6 182.8 172.4 166.4 169.5 258.8 216.2 273.8 85.8 182.4 172.6 229.8 199.6 177.6 230.0 245.6 1408.6 201.6 196.1 236.4 172.2 176.5 201.7 257.4 164.7 218.8 262.6 1039.4 208.2 238.4 137.0 187.3 658.8 226.6 395.5 396.1 440.7 561.4 550.1 566.7 420.5 373.0 301.1 334.0 193.7 514.9 465.6 543.1 217.0 272.3 442.4 439.6 539.2 632.1 302.8 506.1 390.3 299.9 388.2 380.7 288.7 414.7 468.2 447.0 583.2 502.2 433.5 426.5 523.3 327.3 458.9 2403.4 513.8 242.0 755.0 274.0 302.5 378.4 1221.9 244.0 295.4 508.4 485.6 320.7 553.9 455.8 433.3 411.9 234.5 599.4 526.9 437.8 597.3 579.6 629.1 495.7 587.9 567.7 564.9 422.2 1365.1 217.2 241.4 230.8 146.4 233.1 199.7 161.6 186.5 180.7 226.8 130.4 219.3 189.1 155.2 191.0 270.8 87.2 222.2 389.4 149.0 168.8 160.5 170.8 137.6 169.8 166.4 169.5 172.6 172.2 164.7 187.3 193.2 198.7 194.2 41.8 198.3 216.2 219.7 149.0 235.6 134.0 218.2 161.5 572.0 160.2 181.1 128.8 58.4 172.4 155.2 160.8 226.9 198.2 405.5 130.4 178.8 191.3 219.9 232.8 70.8 202.9 208.2 181.7 143.2 174.3 219.1 234.7 156.4 189.1 156.8 99.3 73.7 220.3 120.1 277.9 202.0 639.7 161.8 216.8 220.5 55.3 241.8 195.5 117.4 54.3 86.5 213.8 150.6 225.7 283.6 269.0 240.1 235.5 143.2 121.3 164.3 232.4 274.2 263.3 189.8 247.2 234.0 272.9 193.3 208.2 210.5 283.8 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 6.8" "Group enriched" "Detected in some" 12 "Excitatory neurons: 915.9;Inhibitory neurons: 867.9;Oligodendrocyte precursor cells: 1761.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029007: AB_10601802, HPA029008: " "unprognostic (2.26e-1)" "unprognostic (2.16e-2)" "unprognostic (2.83e-2)" "unprognostic (5.97e-2)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (3.54e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-2)" "unprognostic (5.03e-10)" "unprognostic (1.95e-1)" "unprognostic (4.14e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-3)" 0.0 0.0 6.8 0.0 4.3 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 4.8 0.0 0.0 0.0 0.0 1.9 2.7 0.0 0.2 0.0 0.1 0.0 1.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 4.3 0.0 6.0 5.7 4.8 1.9 2.7 1.6 0.8 5.0 0.7 0.0 0.0 3.0 21.5 0.2 0.3 0.1 0.0 0.0 7.3 0.0 0.0 1.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.5 0.1 0.4 0.0 0.0 915.9 0.0 0.0 0.9 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 867.9 0.0 0.0 0.0 0.8 6.3 0.0 0.3 0.0 19.7 0.0 0.5 0.0 1761.3 92.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.9 0.0 0.4 0.2 17.1 8.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 57000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cell Junctions" "CAB021089: AB_10123543, HPA046119: AB_2679547, HPA063535: AB_2685033" "unprognostic (2.25e-3)" "unprognostic (3.32e-2)" "unprognostic (2.82e-3)" "unprognostic (1.80e-1)" "unprognostic (8.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (4.83e-2)" "unprognostic (2.28e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (6.18e-2)" "prognostic favorable (7.34e-7)" "unprognostic (1.54e-1)" "unprognostic (2.31e-1)" "unprognostic (7.62e-2)" "unprognostic (1.04e-1)" 144.4 137.1 88.3 65.9 110.4 33.1 126.4 102.9 100.6 110.9 103.2 155.8 115.5 99.2 115.7 208.9 113.4 95.6 190.7 83.7 91.3 151.8 82.4 134.4 35.6 106.8 99.4 101.5 83.8 120.4 54.3 124.6 105.2 96.3 122.9 54.0 127.7 104.0 87.1 140.6 115.2 115.5 95.9 66.0 125.3 35.0 100.2 33.0 122.9 62.0 69.3 126.8 126.3 139.0 225.3 161.1 237.9 353.6 202.2 220.8 362.0 222.0 277.9 208.1 261.1 337.9 297.4 0.8 182.9 334.3 228.0 167.7 165.9 366.0 240.0 129.6 144.0 94.3 245.7 206.5 243.6 1.7 88.2 140.5 286.0 249.1 269.6 230.6 397.7 66.0 52.9 94.3 227.2 199.4 2.3 28.9 96.2 237.4 3.6 88.8 138.0 135.7 441.9 295.5 94.9 124.8 409.7 568.2 344.3 503.4 201.5 64.4 341.1 217.1 117.4 136.5 156.5 33.8 69.9 13.5 207.0 40.3 286.7 5.1 37.8 3.4 5.8 46.4 3.8 7.9 4.1 4.3 32.3 6.6 0.3 2.1 20.9 0.6 46.8 7.9 11.1 17.8 88.3 110.4 102.9 100.6 83.7 91.3 106.8 99.4 105.2 95.9 100.2 139.0 137.3 259.6 161.0 57.1 19.4 78.5 119.5 134.4 82.0 7.3 74.6 52.3 230.8 87.2 201.8 121.4 20.9 124.8 21.1 320.7 68.4 184.9 17.2 158.0 67.9 141.1 51.0 41.7 37.6 175.5 137.8 97.1 167.1 206.9 40.5 83.3 92.4 66.6 92.8 3.3 31.5 139.0 87.5 80.5 80.9 23.6 77.9 77.9 78.2 104.0 158.5 46.2 6.2 66.4 159.7 328.7 201.4 84.7 24.8 128.7 165.6 140.1 210.1 24.5 98.6 74.9 109.1 18.1 21.0 111.3 77.3 189.9 20.4 44.4 130.6 181.4 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 539.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 130.8 112.2 106.7 98.7 85.3 162.4 194.3 147.8 87.5 179.4 94.7 141.2 136.9 149.4 84.4 113.7 131.0 121.8 109.9 88.1 105.3 106.5 147.9 132.9 81.9 101.3 112.9 173.9 93.3 137.2 84.7 200.0 94.0 132.3 134.5 88.8 110.9 126.3 87.3 99.0 142.9 178.4 104.9 92.5 81.8 59.5 129.4 95.6 140.6 89.9 99.5 158.3 109.3 108.4 161.6 210.0 423.6 242.8 226.9 184.7 333.8 179.6 249.7 288.2 284.3 146.3 224.0 131.7 157.8 314.1 129.0 119.6 315.8 510.0 306.2 123.3 215.7 215.5 261.0 523.7 169.5 121.8 99.1 271.6 226.7 345.5 208.7 235.7 258.1 63.0 153.7 80.3 324.1 161.8 87.3 68.3 397.2 211.0 159.3 64.9 281.9 88.3 177.9 494.8 102.9 172.4 296.2 147.1 809.4 509.8 242.1 248.6 340.8 217.1 163.6 139.3 264.0 50.7 82.7 138.4 221.5 150.5 369.7 4.7 7.3 6.4 9.2 12.3 10.9 7.7 8.6 10.1 11.8 8.0 8.6 9.4 6.6 9.6 12.6 10.0 10.8 5.6 106.7 85.3 147.8 87.5 88.1 105.3 101.3 112.9 94.0 104.9 129.4 108.4 171.7 137.8 179.5 58.1 71.7 213.5 130.1 75.3 116.1 40.7 232.5 168.1 84.7 90.1 119.2 62.5 33.3 318.9 99.0 251.6 35.2 132.2 11.0 90.3 125.9 187.3 93.8 43.8 50.9 78.5 115.6 116.8 53.0 95.5 116.6 137.0 139.2 172.5 115.1 13.5 82.4 145.9 42.7 154.6 228.1 9.5 59.7 161.1 202.7 124.6 98.3 89.2 49.4 70.9 62.9 139.8 249.5 86.9 55.5 128.3 160.3 93.2 96.1 62.0 46.0 175.6 137.3 78.4 40.1 70.9 174.9 539.5 77.0 245.6 189.6 127.9 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CTNND2 "GT24, NPRAP" ENSG00000169862 "Catenin delta 2" Q9UQB3 5 10971836-11904446 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Developmental protein" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 93.8" "Cell type enhanced" "Detected in many" "Astrocytes: 2382.9;Excitatory neurons: 1253.9;Inhibitory neurons: 1124.0;Oligodendrocyte precursor cells: 1418.0;Oligodendrocytes: 433.8" "Cancer enriched" "Detected in many" 16 "glioma: 44.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.1;MCF7: 9.0;SK-BR-3: 5.3;U-266/84: 17.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015077, CAB037339, HPA071124" Enhanced Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "CAB037339: , HPA015077: AB_2669150, HPA071124: " "unprognostic (7.32e-2)" "unprognostic (1.51e-3)" "unprognostic (2.23e-1)" "unprognostic (5.16e-2)" "unprognostic (5.66e-2)" "unprognostic (2.06e-2)" "unprognostic (1.81e-1)" "unprognostic (2.74e-2)" "unprognostic (9.13e-2)" "unprognostic (9.86e-2)" "unprognostic (8.95e-3)" "unprognostic (2.66e-1)" "unprognostic (9.55e-4)" "unprognostic (5.87e-2)" "unprognostic (1.05e-2)" "unprognostic (1.33e-1)" "unprognostic (4.76e-2)" 0.2 0.7 79.2 0.2 79.3 0.0 0.9 49.7 75.7 0.1 15.2 1.1 0.1 0.1 0.3 0.1 0.2 2.6 3.8 84.6 56.7 0.0 0.5 0.7 0.1 93.8 72.6 0.5 15.8 0.0 9.0 0.3 71.5 0.9 0.3 7.0 0.8 0.2 0.1 0.7 0.5 0.1 77.7 3.9 0.6 2.6 83.7 0.2 0.2 0.1 0.0 0.1 0.2 76.1 0.0 0.2 19.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 9.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.2 0.0 0.0 5.3 0.0 0.6 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.0 17.5 0.0 1.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 79.2 79.3 49.7 75.7 84.6 56.7 93.8 72.6 71.5 77.7 83.7 76.1 0.1 0.0 0.0 2382.9 0.1 0.0 0.1 0.0 0.0 24.0 7.9 4.1 12.7 28.6 0.0 1.8 0.0 0.0 0.0 0.1 3.9 6.5 25.6 0.8 0.1 0.8 4.9 0.0 1253.9 6.1 0.2 0.5 0.0 0.9 0.0 0.0 0.0 0.2 0.1 8.4 1124.0 0.1 0.0 0.0 0.7 31.1 1.5 0.2 0.0 69.3 0.0 33.0 0.0 1418.0 433.8 2.2 0.0 0.0 0.0 2.8 0.0 0.4 0.0 3.6 0.0 3.3 0.3 4.6 5.9 0.0 0.0 0.0 0.1 0.5 0.3 0.1 CTSF "CATSF, CLN13" ENSG00000174080 "Cathepsin F" Q9UBX1 11 66563464-66568879 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 320.9;Muller glia cells: 196.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "SiHa: 23.1;SK-MEL-30: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002141, HPA031431" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 5800000 "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Endoplasmic reticulum, Plasma membrane" "CAB002141: AB_563471, HPA031431: " "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (1.03e-1)" "unprognostic (7.22e-3)" "unprognostic (2.25e-2)" "unprognostic (6.72e-2)" "unprognostic (2.67e-2)" "unprognostic (2.76e-2)" "unprognostic (3.69e-1)" "unprognostic (4.14e-1)" "unprognostic (1.69e-2)" "unprognostic (9.12e-2)" "prognostic favorable (8.92e-7)" "unprognostic (1.36e-2)" "unprognostic (1.28e-1)" "unprognostic (3.89e-1)" "unprognostic (2.42e-1)" 57.8 70.0 68.1 0.8 76.3 0.3 62.2 74.5 74.0 78.8 90.2 76.7 3.0 89.2 21.9 15.6 70.8 10.0 100.2 63.2 74.2 46.9 66.0 32.9 3.6 75.0 70.3 99.1 31.7 20.0 43.3 3.8 68.4 53.5 3.5 26.2 55.7 17.1 91.9 44.4 29.5 12.2 77.2 25.0 54.3 109.7 71.0 3.0 40.6 27.6 3.0 56.6 58.7 86.6 0.0 17.0 3.1 5.4 14.2 8.6 3.4 13.0 11.4 6.3 2.3 0.0 2.2 0.0 21.3 10.4 0.0 1.2 6.8 2.6 4.8 3.7 0.0 0.5 7.0 0.0 9.9 0.3 4.4 22.3 9.1 0.8 1.6 13.7 3.8 2.0 5.4 1.6 5.2 4.6 0.1 1.7 0.9 3.7 9.7 0.0 0.0 1.5 7.1 0.3 4.3 6.9 23.1 0.3 59.5 0.3 7.4 0.6 3.3 1.8 2.9 1.5 1.2 21.2 0.2 0.0 2.2 0.0 2.9 0.0 0.4 0.3 3.9 0.6 4.1 1.5 3.5 4.6 0.6 1.4 6.4 4.1 0.1 4.6 0.2 0.9 1.3 2.2 68.1 76.3 74.5 74.0 63.2 74.2 75.0 70.3 68.4 77.2 71.0 86.6 36.6 12.8 15.6 31.3 5.9 39.8 62.4 8.5 37.5 107.9 45.3 80.6 57.9 41.5 7.4 36.8 41.7 31.6 9.6 0.6 15.6 13.1 163.3 1.7 22.8 27.2 12.0 11.4 26.5 7.5 9.5 118.1 8.2 5.3 9.5 52.1 56.0 67.8 14.9 134.6 31.3 3.1 18.3 21.5 32.8 320.9 145.7 13.1 156.5 12.2 3.1 196.6 17.5 21.6 29.4 5.9 3.2 121.9 12.9 50.5 1.3 44.7 3.3 77.9 78.9 62.0 45.9 169.6 43.3 3.6 25.3 23.7 9.5 30.7 4.3 32.9 CTSV "CTSL2, CTSU" ENSG00000136943 "Cathepsin V" O60911 9 97029677-97156556 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "lymphoid tissue: 643.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 63.7;Cytotrophoblasts: 122.3;Extravillous trophoblasts: 153.0;Granulosa cells: 54.2;Syncytiotrophoblasts: 67.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 15.1" "Lineage enriched" "Detected in many" 4 "dendritic cells: 15.1" "Group enriched" "Detected in many" 8 "BEWO: 592.6;SuSa: 739.0" "Low region specificity" "Detected in all" CAB017112 Uncertain Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoli fibrillar center, Cytosol" "Nucleoplasm, Plasma membrane" "CAB017112: " "unprognostic (2.40e-1)" "unprognostic (2.74e-2)" "unprognostic (1.50e-1)" "prognostic favorable (8.41e-4)" "unprognostic (7.29e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (2.83e-5)" "unprognostic (7.04e-3)" "unprognostic (6.06e-2)" "unprognostic (1.39e-2)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.86e-2)" "unprognostic (1.78e-1)" "unprognostic (2.41e-2)" "unprognostic (1.33e-1)" "unprognostic (3.04e-3)" "prognostic unfavorable (2.39e-4)" 0.2 0.2 0.6 0.3 0.7 0.3 5.8 0.8 1.6 43.1 0.8 2.9 1.1 2.8 1.7 19.8 1.3 0.5 0.1 0.6 0.5 21.3 0.2 0.9 0.1 0.7 0.6 0.2 2.1 1.4 1.5 16.8 0.6 0.7 3.2 17.2 9.4 0.1 0.7 52.5 0.4 0.8 0.5 0.2 2.8 65.8 0.6 643.6 1.3 0.1 6.0 0.4 20.1 1.0 37.1 5.2 12.1 33.1 0.6 0.0 592.6 0.5 0.0 7.1 4.7 81.0 37.7 0.3 2.8 0.5 50.5 67.2 58.8 43.9 9.7 0.1 4.4 0.8 1.9 3.1 0.2 0.1 3.3 0.0 9.2 1.5 0.8 0.9 2.4 8.5 0.5 0.2 14.4 15.2 0.9 0.3 76.2 78.9 10.7 0.0 27.3 0.1 11.4 3.7 2.4 3.6 39.1 13.1 13.2 739.0 21.1 3.2 0.0 1.0 23.6 0.2 3.5 5.7 20.6 0.8 1.6 0.4 4.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.1 0.0 0.2 3.3 0.0 15.1 0.0 0.1 0.6 0.7 0.8 1.6 0.6 0.5 0.7 0.6 0.6 0.5 0.6 1.0 0.9 0.0 1.1 0.3 0.9 30.3 13.0 63.7 19.9 4.6 13.1 9.9 1.3 0.0 17.4 1.8 10.4 122.3 6.9 4.7 1.9 1.8 2.6 15.0 2.9 1.8 1.8 0.0 0.6 0.8 153.0 3.2 0.0 24.0 0.0 54.2 0.4 0.0 13.6 0.0 0.9 1.5 10.2 0.8 3.0 8.2 4.1 2.4 0.0 0.0 0.2 6.5 0.0 0.0 3.5 0.5 10.5 1.2 0.0 8.1 0.1 22.1 4.2 36.6 6.6 1.4 3.6 46.7 33.7 8.2 11.9 67.3 0.5 0.7 4.2 8.4 CTTN EMS1 ENSG00000085733 Cortactin Q14247 11 70398404-70436584 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 1.2;neutrophil: 2.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.1" "Cell line enhanced" "Detected in many" "A-431: 450.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011235, HPA057242" Supported Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA 11000000 "Cluster 34: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Golgi apparatus, Vesicles" "CAB011235: , HPA057242: AB_2683379" "unprognostic (6.34e-2)" "unprognostic (2.65e-2)" "unprognostic (2.05e-1)" "unprognostic (3.13e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (2.19e-6)" "prognostic unfavorable (4.45e-4)" "unprognostic (6.10e-2)" "unprognostic (2.39e-1)" "unprognostic (1.10e-1)" "unprognostic (1.25e-3)" "unprognostic (1.20e-1)" "unprognostic (1.50e-2)" "unprognostic (6.97e-2)" "unprognostic (2.79e-1)" "unprognostic (3.72e-3)" "unprognostic (1.94e-1)" 91.7 142.5 28.3 15.6 30.0 4.9 82.9 29.7 32.3 112.3 28.5 84.9 28.4 117.8 18.7 131.6 85.0 35.1 106.9 27.7 28.2 109.6 66.9 74.8 9.0 33.2 30.8 112.9 79.5 18.1 94.1 23.9 30.9 101.6 23.8 8.4 92.9 27.0 65.7 104.4 70.9 31.8 29.5 53.3 92.2 62.0 30.3 8.7 89.5 14.5 12.7 88.1 101.2 32.5 450.2 97.2 32.0 37.2 53.2 81.9 52.5 93.8 92.5 80.7 63.4 129.5 110.3 17.5 90.6 121.1 86.3 97.3 38.6 98.7 58.7 35.5 39.1 1.7 73.6 61.1 113.9 0.4 22.6 116.6 68.0 89.4 50.2 84.4 68.8 0.5 51.3 3.3 80.9 122.9 0.9 6.4 35.0 163.4 58.6 0.2 39.3 14.3 90.5 143.7 26.3 44.9 68.3 93.2 158.0 57.2 75.8 1.9 86.8 70.8 45.3 111.2 63.6 7.4 5.2 1.0 141.1 0.4 98.9 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 2.1 0.0 0.1 0.4 0.0 6.8 28.3 30.0 29.7 32.3 27.7 28.2 33.2 30.8 30.9 29.5 30.3 32.5 95.3 44.8 51.8 61.7 4.0 151.9 102.8 85.8 46.1 39.4 81.0 57.9 64.1 80.1 95.4 134.3 18.8 83.8 1.6 224.4 64.6 146.5 12.4 86.4 84.8 89.9 74.4 18.9 93.4 221.5 95.6 89.1 76.0 116.1 6.3 117.7 78.9 44.1 10.4 38.7 65.4 123.8 57.0 8.9 34.1 26.1 103.2 38.6 122.7 28.1 5.9 42.5 0.0 40.2 145.8 260.6 177.8 98.9 3.1 153.5 108.4 164.3 89.4 32.5 59.2 61.0 87.5 32.0 47.0 76.7 174.9 106.3 5.4 91.4 111.9 258.1 CTXN1 FLJ25968 ENSG00000178531 "Cortexin 1" P60606 19 7924491-7926135 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 275.1;endometrium 1: 85.7" "Cell type enriched" "Detected in many" 4 "Endometrial ciliated cells: 127.7" "Group enriched" "Detected in all" 4 "endometrial cancer: 69.5;glioma: 56.3;ovarian cancer: 138.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 96.4;HEK 293: 67.5;NTERA-2: 72.4;REH: 57.3;SCLC-21H: 56.2;SH-SY5Y: 94.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016669 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA016669: AB_1847330" "unprognostic (1.49e-2)" "unprognostic (3.52e-2)" "unprognostic (1.79e-2)" "unprognostic (2.47e-1)" "unprognostic (1.22e-1)" "unprognostic (1.82e-2)" "unprognostic (5.42e-2)" "unprognostic (2.17e-1)" "unprognostic (2.58e-1)" "unprognostic (2.28e-2)" "unprognostic (1.69e-3)" "unprognostic (3.31e-2)" "unprognostic (1.56e-3)" "unprognostic (4.84e-2)" "unprognostic (3.09e-2)" "unprognostic (3.76e-2)" "unprognostic (9.41e-2)" 6.5 12.5 176.3 0.9 275.1 0.1 3.2 0.0 173.0 36.9 0.0 61.3 0.9 85.7 2.9 2.6 43.0 0.2 1.0 199.1 58.0 11.7 0.4 7.0 0.0 0.0 21.3 6.2 2.2 1.1 57.0 0.3 1.0 16.3 0.4 0.2 6.4 12.4 0.5 4.1 4.7 4.9 0.0 1.4 8.8 27.8 85.5 0.3 2.8 0.1 0.0 21.2 13.2 40.7 33.5 8.1 20.5 96.4 0.0 0.3 4.8 8.5 2.3 4.1 2.4 2.4 5.0 0.2 16.2 2.0 2.2 35.9 4.7 0.9 0.2 3.0 67.5 0.7 5.3 1.5 0.9 1.8 1.9 0.0 2.7 1.4 0.9 9.8 5.4 9.1 21.3 0.3 0.5 40.5 18.5 13.6 72.4 2.4 34.1 57.3 0.0 6.4 15.0 1.4 56.2 94.5 5.2 2.8 9.9 1.7 21.2 0.6 8.3 2.1 33.1 3.9 4.8 0.7 1.0 4.8 8.0 3.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 176.3 275.1 0.0 173.0 199.1 58.0 0.0 21.3 1.0 0.0 85.5 40.7 0.6 0.0 0.0 3.3 0.7 1.1 4.1 1.5 2.2 0.3 15.3 6.7 0.4 1.5 1.0 9.2 4.2 0.2 0.2 0.5 3.9 7.8 9.5 127.7 22.4 1.6 9.1 0.0 20.6 0.4 0.4 3.0 0.0 7.9 0.0 13.3 0.7 0.1 0.3 0.0 3.5 0.5 2.0 0.3 0.5 27.1 1.2 0.5 1.8 4.7 0.0 0.6 0.0 1.5 2.9 1.7 1.2 1.9 0.0 19.9 0.0 11.9 21.0 0.4 0.0 0.2 17.7 6.0 16.0 0.3 2.0 0.3 0.6 3.2 0.2 6.4 CUEDC1 ENSG00000180891 "CUE domain containing 1" Q9NWM3 17 57861243-57955412 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 64.6;Oligodendrocytes: 117.9;Rod photoreceptor cells: 64.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "plasmacytoid DC: 21.7" "Lineage enriched" "Detected in many" 9 "dendritic cells: 21.7" "Cell line enhanced" "Detected in many" "T-47d: 116.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023050, HPA024836" Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Centrosome "HPA023050: AB_1847332, HPA024836: AB_1847333" "unprognostic (4.46e-1)" "unprognostic (3.76e-3)" "unprognostic (4.77e-2)" "unprognostic (4.87e-3)" "unprognostic (4.04e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (2.65e-5)" "unprognostic (6.69e-2)" "unprognostic (1.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "prognostic favorable (8.46e-4)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (2.52e-2)" "unprognostic (2.65e-2)" 20.5 19.2 19.1 13.9 29.5 8.6 17.2 23.2 22.8 31.5 20.6 40.9 7.6 24.7 7.9 32.4 32.4 19.7 38.8 16.6 22.5 25.1 6.1 21.2 7.5 29.5 27.5 9.5 19.0 11.3 21.6 11.9 24.0 24.4 10.6 30.4 30.9 26.3 86.6 11.7 13.2 25.6 21.9 10.6 23.2 3.2 27.8 5.5 18.2 39.7 5.5 31.3 21.2 33.8 27.1 81.7 83.7 15.1 13.5 24.4 2.8 18.8 37.6 38.5 27.7 15.1 100.9 0.4 74.3 36.2 32.6 21.2 9.3 40.1 13.7 52.8 15.8 0.9 58.4 12.6 32.1 0.3 6.3 25.2 23.7 22.5 18.9 33.8 18.8 0.5 1.1 0.4 35.8 15.2 1.4 0.6 2.9 30.7 22.5 2.8 21.6 4.0 25.8 17.5 34.5 18.9 7.9 8.4 32.0 14.2 116.8 2.9 24.2 101.9 63.4 28.2 42.4 0.0 0.4 0.4 44.3 3.7 83.3 0.7 0.5 2.5 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.2 1.9 21.7 0.0 0.2 19.1 29.5 23.2 22.8 16.6 22.5 29.5 27.5 24.0 21.9 27.8 33.8 14.1 19.2 5.9 22.5 0.9 4.1 15.6 6.5 13.1 47.1 11.5 11.6 16.1 17.2 10.4 22.0 64.6 0.7 30.9 6.2 7.9 20.3 0.4 24.6 6.3 10.7 3.5 0.0 4.8 26.3 0.4 15.8 10.2 22.9 0.0 10.0 3.9 3.4 17.3 10.1 13.0 4.5 18.3 11.3 7.3 2.9 6.8 12.9 5.4 30.9 4.3 31.8 0.0 31.2 117.9 27.7 2.1 5.3 0.1 21.8 0.7 8.6 17.6 64.8 6.6 26.6 15.3 0.0 1.3 19.0 2.4 0.7 0.7 1.6 4.2 17.3 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 10.4;Endometrial ciliated cells: 41.3;Gastric mucus-secreting cells: 10.7;Glandular and luminal cells: 21.1;Paneth cells: 15.4;Respiratory ciliated cells: 29.5;Undifferentiated cells: 15.0" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 6.0 0.0 16.9 0.4 0.6 0.4 21.0 14.5 0.0 0.0 0.0 0.0 9.0 0.7 0.7 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 42.8 15.6 0.0 3.0 7.7 0.0 25.5 0.0 0.8 0.1 0.0 9.6 0.0 0.1 0.1 10.2 0.0 1.5 2.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 1.9 0.1 0.8 0.0 0.0 0.6 0.1 0.6 0.0 2.3 7.3 0.0 0.0 0.0 10.4 1.9 0.0 0.2 41.3 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 10.7 21.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 15.4 0.0 0.0 7.6 0.0 2.9 29.5 0.0 0.0 0.0 0.5 0.0 0.5 3.2 9.1 0.0 0.2 0.0 15.0 0.3 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Group enriched" "Detected in some" 5 "Microglial cells: 177.1;NK-cells: 350.1" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 449.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 21 "RPMI-8226: 589.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" 2.3 3.8 6.2 6.9 6.4 1.1 5.1 8.6 6.0 2.7 1.7 1.1 1.2 2.7 4.2 0.8 6.1 2.6 2.4 7.7 8.4 2.5 2.0 9.9 2.1 17.3 14.8 1.6 0.7 4.5 1.0 4.6 18.9 3.5 1.1 0.5 7.6 7.2 6.5 2.3 0.9 3.5 21.5 11.9 1.4 1.8 17.4 2.0 2.4 2.2 5.3 2.4 0.3 26.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.2 6.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 24.5 0.0 0.2 0.2 0.5 0.1 0.0 0.0 0.2 0.1 589.8 0.0 0.0 0.1 0.1 0.0 8.1 0.0 0.2 0.1 16.5 0.0 0.0 0.1 0.1 0.0 0.5 1.0 0.1 0.0 28.6 0.0 7.7 99.6 1.8 264.0 261.2 3.4 0.8 55.9 145.2 94.4 0.7 19.0 122.4 20.8 39.7 449.2 7.1 1.5 232.7 6.2 6.4 8.6 6.0 7.7 8.4 17.3 14.8 18.9 21.5 17.4 26.4 0.8 0.0 0.5 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.8 3.8 0.4 0.0 0.6 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.2 0.2 0.1 3.5 0.0 2.1 0.3 0.0 0.0 0.3 0.0 0.0 5.1 0.1 0.7 0.3 4.1 0.0 0.6 0.0 0.0 15.0 28.0 0.3 0.3 43.2 0.0 177.1 50.3 0.1 350.1 2.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.7 0.2 6.6 0.4 1.3 0.7 0.2 0.0 0.6 0.0 22.6 0.1 0.1 0.0 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CXCR2 "CD182, CMKAR2, IL8RB" ENSG00000180871 "C-X-C motif chemokine receptor 2" P25025 2 218125289-218137251 "Cancer-related genes, CD markers, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 27.2;lymphoid tissue: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 10.5;dendritic cells: 12.9;granulocytes: 6.3;NK-cells: 40.2;Squamous epithelial cells: 11.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Immune cell enriched" "Detected in many" 52 "neutrophil: 3273.9" "Lineage enriched" "Detected in many" 111 "granulocytes: 3273.9" "Group enriched" "Detected in some" 11 "BEWO: 14.5;HL-60: 8.2;HMC-1: 16.5;THP-1: 15.3;U-937: 15.1" "Low region specificity" "Detected in all" "CAB016268, HPA031999, HPA032017" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Mitotic spindle" Yes NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Microtubules, Mitotic spindle" "CAB016268: AB_626893, HPA031999: AB_2674105, HPA032017: AB_2674112" "unprognostic (4.89e-2)" "unprognostic (2.01e-1)" "unprognostic (5.63e-2)" "unprognostic (1.10e-2)" "unprognostic (1.58e-1)" "unprognostic (3.13e-1)" "unprognostic (1.33e-1)" "unprognostic (2.13e-1)" "unprognostic (5.96e-2)" "unprognostic (1.22e-2)" "unprognostic (5.67e-2)" "unprognostic (1.41e-1)" "unprognostic (7.54e-2)" "unprognostic (1.04e-1)" "unprognostic (7.23e-2)" "unprognostic (8.18e-2)" "unprognostic (5.48e-2)" 13.8 1.5 0.3 40.0 0.6 7.3 0.8 0.2 2.6 4.5 0.1 0.9 0.2 0.4 1.3 27.2 2.9 7.8 1.0 0.3 0.1 0.4 2.4 6.5 0.7 0.6 0.5 0.4 2.9 0.4 0.2 4.6 1.4 0.6 0.7 0.0 3.0 3.8 0.5 4.8 1.2 2.4 0.3 27.3 0.7 0.2 0.5 2.8 0.6 11.6 3.0 7.8 7.3 0.4 0.0 0.0 0.1 0.0 0.0 0.0 14.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.2 16.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 1.3 0.2 0.0 0.0 0.4 0.0 1.3 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.5 0.0 15.3 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 15.1 0.0 63.5 29.5 50.3 28.8 7.4 0.4 0.2 1.3 7.3 13.5 0.2 1.1 9.9 3273.9 6.8 3.6 25.0 0.5 17.4 0.3 0.6 0.2 2.6 0.3 0.1 0.6 0.5 1.4 0.3 0.5 0.4 0.0 0.0 10.5 0.0 0.1 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.2 0.0 1.9 0.0 0.0 0.7 12.9 0.0 0.0 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.5 1.2 0.0 0.0 6.3 3.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.2 1.6 0.0 0.0 2.8 0.0 1.0 3.7 0.0 40.2 0.0 0.1 0.0 2.2 0.0 1.4 0.1 0.0 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.0 11.6 0.1 0.3 4.1 0.1 0.1 1.9 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82442586-82450829 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 47.4;Ductal cells: 39.7;Granulosa cells: 56.1;Hofbauer cells: 80.2;monocytes: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cell Junctions" "HPA045696: AB_2679421" "unprognostic (1.87e-2)" "unprognostic (6.92e-3)" "unprognostic (2.25e-1)" "unprognostic (2.15e-3)" "unprognostic (5.75e-2)" "unprognostic (2.05e-3)" "unprognostic (3.81e-3)" "unprognostic (4.86e-2)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-3)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.83e-11)" "unprognostic (1.47e-1)" "unprognostic (5.51e-2)" "unprognostic (7.78e-2)" "unprognostic (9.14e-3)" 39.2 35.7 34.4 70.1 36.1 37.2 37.4 36.7 42.6 40.9 36.3 33.8 24.6 33.7 23.7 34.1 34.9 46.0 30.7 33.2 35.6 51.2 64.9 41.4 110.5 41.8 37.8 33.8 45.0 24.5 25.9 30.7 37.7 43.4 27.7 9.9 30.8 23.2 14.9 29.4 49.3 40.7 37.1 117.4 36.9 17.8 36.7 63.3 28.9 13.6 72.1 49.7 28.2 40.6 48.5 67.4 37.1 61.4 57.9 60.6 35.0 42.2 51.6 61.8 73.1 26.2 47.8 122.4 37.8 60.6 75.4 48.3 25.7 32.4 42.6 87.4 21.1 33.4 19.2 30.6 59.3 38.1 94.4 68.5 45.7 53.1 29.3 59.0 81.5 90.3 28.4 88.2 52.9 50.8 160.2 33.0 27.5 65.0 35.3 120.1 22.7 93.1 44.8 60.7 31.7 60.7 77.0 88.1 55.7 66.3 91.4 148.3 27.9 46.7 46.0 79.3 45.9 157.8 58.3 93.1 61.2 61.0 42.5 223.8 136.7 182.9 96.3 181.3 74.7 114.8 88.2 93.6 125.2 115.9 73.0 71.1 300.6 104.5 169.4 130.9 101.1 161.4 34.4 36.1 36.7 42.6 33.2 35.6 41.8 37.8 37.7 37.1 36.7 40.6 35.6 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 19.0 17.1 0.0 0.0 0.0 22.0 0.0 27.6 47.4 0.0 9.8 39.7 0.0 11.9 21.9 12.9 0.0 0.0 0.0 33.6 36.1 10.9 0.0 12.4 0.0 56.1 0.0 0.0 80.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 54.8 0.0 0.0 0.0 0.0 34.9 0.0 0.0 11.1 0.0 0.0 19.6 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 27.6 19.5 23.8 0.0 0.0 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 CYFIP2 PIR121 ENSG00000055163 "Cytoplasmic FMR1 interacting protein 2" Q96F07 5 157266079-157395595 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 112.2;kidney: 139.9" "Cell type enhanced" "Detected in many" "Astrocytes: 133.5;Collecting duct cells: 158.2;Distal tubular cells: 174.1;Excitatory neurons: 117.7;Inhibitory neurons: 147.5;Oligodendrocyte precursor cells: 120.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 202.4;JURKAT: 145.2;MOLT-4: 204.8;U-266/70: 153.6;U-698: 142.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB055519, HPA068106, HPA071459" Uncertain Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Endoplasmic reticulum" "Plasma membrane, Cytosol" "CAB055519: , HPA068106: AB_2685955, HPA071459: AB_2686400" "unprognostic (1.02e-2)" "unprognostic (1.30e-1)" "unprognostic (7.07e-2)" "prognostic unfavorable (2.42e-6)" "unprognostic (3.76e-1)" "unprognostic (4.58e-2)" "unprognostic (1.14e-1)" "unprognostic (6.91e-3)" "unprognostic (3.97e-2)" "unprognostic (5.25e-2)" "prognostic favorable (1.18e-4)" "unprognostic (3.81e-2)" "prognostic favorable (3.21e-12)" "unprognostic (2.90e-1)" "unprognostic (1.38e-1)" "unprognostic (3.03e-1)" "unprognostic (2.49e-2)" 3.2 12.3 61.0 30.8 54.4 55.5 2.8 23.6 103.8 3.1 16.3 8.9 6.3 6.6 25.1 3.8 9.2 8.8 10.4 112.2 25.6 139.9 18.3 12.2 57.1 8.4 33.4 4.8 7.1 64.9 40.1 9.3 6.6 5.8 9.8 35.4 4.0 5.0 7.0 2.8 17.5 5.6 0.0 35.0 20.9 5.3 67.7 85.9 9.9 1.7 55.3 8.3 2.3 37.7 0.3 31.8 47.3 28.8 1.1 1.3 81.5 6.1 9.6 2.5 6.8 6.2 0.6 202.4 14.5 3.4 7.4 0.4 38.0 27.1 5.8 48.8 60.8 28.4 42.3 24.9 4.1 29.1 71.8 5.4 10.9 8.1 0.5 18.8 8.8 145.2 0.4 81.1 7.0 7.7 204.8 5.5 22.3 0.5 8.5 50.6 1.4 102.3 24.5 30.2 70.5 27.4 0.6 28.3 4.6 46.8 19.9 0.8 11.3 2.0 21.4 7.1 5.4 153.6 40.2 142.8 21.4 33.5 11.8 64.8 12.6 90.1 85.9 57.4 61.0 35.8 60.6 75.7 17.8 35.9 63.2 73.2 41.0 53.9 133.7 43.9 53.5 78.0 61.0 54.4 23.6 103.8 112.2 25.6 8.4 33.4 6.6 0.0 67.7 37.7 1.8 3.2 26.9 133.5 76.6 1.1 2.2 2.8 3.4 62.0 3.5 3.4 17.9 8.6 7.4 158.2 16.7 37.2 78.8 6.0 174.1 9.7 15.3 2.8 1.8 2.6 14.4 11.6 117.7 1.6 43.0 3.6 6.1 6.2 2.5 23.1 5.7 30.8 5.3 90.9 147.5 5.6 4.1 6.5 11.4 24.2 1.8 15.7 7.2 23.4 20.3 14.0 101.0 120.6 33.8 1.9 9.9 6.8 41.1 1.3 5.4 55.0 4.7 35.2 0.0 12.2 11.0 3.2 13.1 0.8 1.4 21.1 88.8 2.1 9.1 1.7 CYP20A1 CYP-M ENSG00000119004 "Cytochrome P450 family 20 subfamily A member 1" Q6UW02 2 203238977-203306026 "Predicted intracellular proteins, Predicted membrane proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA055872, HPA058461" Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions,Actin filaments" No No "Cluster 24: B-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions, Actin filaments" Nucleoplasm "HPA055872: AB_2682951, HPA058461: AB_2683725" "unprognostic (4.72e-2)" "unprognostic (2.06e-2)" "unprognostic (1.20e-2)" "unprognostic (2.14e-2)" "unprognostic (1.42e-1)" "unprognostic (3.06e-2)" "unprognostic (5.21e-2)" "unprognostic (2.58e-2)" "unprognostic (4.21e-2)" "unprognostic (2.62e-2)" "unprognostic (4.53e-2)" "unprognostic (4.42e-2)" "unprognostic (7.64e-3)" "unprognostic (9.39e-2)" "unprognostic (2.18e-1)" "unprognostic (1.23e-2)" "unprognostic (1.95e-3)" 3.1 3.2 3.1 2.1 4.3 2.2 2.4 4.1 3.4 2.7 4.2 3.6 2.1 2.3 2.4 2.4 1.9 3.2 1.7 2.7 3.0 6.1 4.6 3.5 3.9 4.5 3.8 3.8 3.1 2.9 0.9 3.4 3.8 3.5 3.2 1.7 2.3 2.1 2.6 3.8 2.6 3.2 2.9 3.7 3.7 2.9 4.2 2.2 8.0 1.3 2.9 3.2 1.0 5.7 2.8 4.7 2.9 2.9 12.1 2.9 2.5 5.0 3.3 2.4 1.7 9.1 5.2 1.9 3.8 4.8 4.4 4.0 1.9 2.7 4.6 2.9 1.0 6.1 3.0 3.5 7.2 6.4 3.3 5.5 2.2 5.7 4.9 2.1 6.4 2.8 8.0 9.9 5.1 4.2 4.3 3.7 7.7 2.3 4.2 3.5 3.7 4.5 3.2 9.2 2.0 2.2 0.4 4.0 5.5 3.3 2.7 4.8 8.5 8.4 2.5 4.0 4.1 5.2 4.4 2.3 6.4 2.8 3.6 5.7 5.2 2.1 6.5 5.6 7.1 6.1 8.0 5.9 2.3 9.6 5.9 3.5 3.0 4.9 6.5 7.4 8.0 4.3 3.1 4.3 4.1 3.4 2.7 3.0 4.5 3.8 3.8 2.9 4.2 5.7 41.2 16.0 33.2 24.2 55.5 12.4 41.6 20.2 29.6 42.0 17.1 17.8 33.6 50.1 33.8 16.5 58.4 33.4 55.8 40.3 11.7 18.3 96.6 24.2 33.6 40.5 45.4 45.5 12.1 20.3 23.0 49.0 53.0 23.7 29.1 65.4 88.2 50.4 37.9 50.5 20.5 33.0 22.4 38.1 22.5 21.9 123.0 35.8 7.2 34.7 44.5 32.4 74.2 24.1 39.1 15.2 30.6 83.8 51.7 33.6 30.8 26.2 23.5 70.5 65.7 76.6 45.7 104.5 64.1 25.4 13.4 40.8 54.4 59.7 32.8 28.7 CYP24A1 "CP24, CYP24, P450-CC24" ENSG00000019186 "Cytochrome P450 family 24 subfamily A member 1" Q07973 20 54153446-54173986 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "endometrium 1: 14.9;kidney: 35.3;lymphoid tissue: 10.5;placenta: 10.0;urinary bladder: 28.7" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 48.3;Basal respiratory cells: 142.7;Basal squamous epithelial cells: 74.0;Club cells: 47.0;Proximal tubular cells: 61.3;Urothelial cells: 36.7" "Cancer enhanced" "Detected in many" "lung cancer: 18.3;urothelial cancer: 21.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 17 "A549: 411.5;Hep G2: 122.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA022261, HPA063771" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 7: Kidney - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA022261: AB_1847427, HPA063771: AB_2685120" "unprognostic (1.19e-7)" "unprognostic (1.73e-1)" "unprognostic (2.24e-2)" "unprognostic (7.69e-3)" "unprognostic (3.30e-1)" "unprognostic (2.30e-2)" "unprognostic (1.11e-2)" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (5.37e-3)" "unprognostic (1.23e-1)" "unprognostic (6.05e-2)" "unprognostic (5.98e-2)" "unprognostic (1.36e-1)" "unprognostic (4.38e-2)" "unprognostic (2.12e-1)" 0.0 0.0 0.2 0.4 0.4 0.0 3.7 0.0 0.3 1.7 0.0 0.0 0.1 14.9 0.2 3.8 0.2 0.0 0.0 0.1 1.8 35.3 0.4 0.7 0.2 0.4 2.0 0.0 0.0 0.0 0.2 10.0 0.3 2.9 0.0 0.0 0.3 2.0 0.0 0.9 0.0 0.2 0.1 0.0 0.0 0.0 0.6 0.2 1.3 0.0 10.5 28.7 1.3 0.2 0.5 411.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 12.6 0.0 3.2 0.0 0.9 15.8 0.0 0.1 0.1 0.0 0.0 0.0 6.5 122.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.7 0.0 7.0 1.3 0.0 2.6 0.6 0.0 0.1 0.1 0.0 0.0 0.0 16.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.1 1.8 0.4 2.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 1.3 22.8 48.3 142.7 74.0 0.0 11.0 8.6 0.4 0.0 47.0 0.0 0.0 0.1 0.1 0.1 5.9 0.1 0.0 0.7 0.5 0.3 0.0 0.0 0.2 0.0 0.1 2.0 0.0 4.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 9.8 0.0 61.3 13.1 0.0 0.0 0.0 0.6 0.0 0.0 3.3 19.6 0.1 0.1 0.0 0.2 36.7 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 CYTH2 "ARNO, CTS18.1, cytohesin-2, PSCD2, PSCD2L, Sec7p-L, Sec7p-like" ENSG00000105443 "Cytohesin 2" Q99418 19 48469208-48482314 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB014872, HPA060662" Uncertain Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 10: Non-specific - Unknown function" Cytosol "Golgi apparatus, Plasma membrane" "CAB014872: , HPA060662: AB_2732652" "unprognostic (2.28e-1)" "unprognostic (1.27e-1)" "unprognostic (7.60e-3)" "unprognostic (1.72e-1)" "unprognostic (4.97e-2)" "unprognostic (4.10e-2)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.66e-1)" "unprognostic (2.83e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (2.33e-2)" "unprognostic (9.19e-2)" "unprognostic (3.14e-1)" "unprognostic (1.22e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.21e-4)" 8.1 12.1 17.2 11.4 17.8 8.1 14.2 20.3 19.0 15.9 15.4 9.3 21.5 10.7 13.6 15.3 7.6 23.2 7.4 16.2 17.1 21.0 7.2 11.2 8.2 18.1 19.1 7.5 16.6 19.6 14.8 16.3 17.4 15.0 8.3 39.0 22.6 9.1 3.6 15.1 21.3 8.2 15.3 10.6 17.5 35.6 21.2 14.9 52.5 5.7 8.8 10.9 10.6 21.2 24.7 36.8 107.9 24.7 16.2 13.9 19.6 18.9 17.3 19.9 18.7 20.1 32.9 16.1 19.2 16.6 16.5 30.4 21.1 23.1 12.5 24.6 28.1 22.5 52.6 22.0 14.6 14.0 29.7 18.0 38.5 24.6 15.9 90.2 26.0 23.4 22.9 55.0 26.6 20.0 23.9 102.5 11.8 22.1 14.9 29.6 15.9 11.2 34.2 52.1 31.9 30.9 20.7 57.6 16.8 34.0 27.1 18.8 28.3 42.6 21.3 10.3 27.8 54.1 30.8 10.8 15.5 27.1 30.7 2.8 2.7 2.3 2.6 2.1 1.8 2.6 3.2 3.7 2.4 1.8 2.8 2.0 7.2 1.4 2.7 3.9 3.6 2.1 17.2 17.8 20.3 19.0 16.2 17.1 18.1 19.1 17.4 15.3 21.2 21.2 48.5 28.9 33.5 15.0 18.7 45.9 115.0 81.1 26.7 35.6 47.6 28.7 11.5 55.8 63.2 40.5 25.0 51.2 42.6 35.0 35.2 82.7 285.9 85.3 26.5 56.0 26.0 4.6 5.7 93.6 47.0 33.5 55.0 56.3 17.7 32.5 50.3 8.3 43.7 21.9 6.8 29.3 67.1 27.9 39.7 163.0 37.3 34.9 35.6 9.4 52.0 42.6 22.6 4.5 12.0 136.6 36.2 36.9 23.2 77.1 57.9 53.3 80.6 59.5 52.6 42.9 70.9 63.5 53.2 23.2 47.5 142.7 33.2 26.0 25.4 139.2 CYTH4 "CYT4, cytohesin-4, PSCD4" ENSG00000100055 "Cytohesin 4" Q9UIA0 22 37282027-37315341 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.3;lymphoid tissue: 67.3" "Cell type enhanced" "Detected in many" "dendritic cells: 117.5;granulocytes: 57.0;Hofbauer cells: 76.8;Kupffer cells: 71.5;Langerhans cells: 87.5;Macrophages: 55.0;NK-cells: 120.5;T-cells: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 34.1;HMC-1: 141.1;THP-1: 95.2;U-266/70: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004065, HPA071573" Approved Supported "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cytokinetic bridge, Centriolar satellite, Cytosol" "HPA004065: , HPA071573: AB_2686418" "unprognostic (4.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.03e-2)" "unprognostic (9.28e-3)" "unprognostic (9.25e-2)" "unprognostic (1.69e-2)" "unprognostic (1.50e-1)" "unprognostic (5.84e-2)" "unprognostic (3.30e-3)" "unprognostic (1.23e-1)" "unprognostic (3.31e-2)" "unprognostic (8.42e-2)" "prognostic unfavorable (2.41e-8)" "unprognostic (3.70e-2)" "unprognostic (1.92e-2)" "unprognostic (5.56e-2)" "unprognostic (2.07e-1)" 21.5 8.8 4.9 67.3 4.5 58.3 5.1 4.4 8.5 5.3 6.0 10.7 8.5 4.4 1.6 6.1 4.8 16.4 5.6 4.7 5.6 4.1 5.7 18.9 57.0 8.8 7.4 3.4 2.5 2.1 2.9 28.0 7.8 3.6 10.0 0.3 7.3 4.3 2.2 2.2 15.2 12.9 6.7 59.2 11.5 2.7 9.7 25.6 3.0 5.1 40.3 23.2 2.5 9.1 0.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 9.3 0.3 0.0 2.5 0.1 0.0 0.6 0.0 5.3 0.0 9.8 0.0 0.0 0.0 34.1 141.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 23.2 0.0 0.0 0.5 13.5 0.0 0.1 1.0 1.3 0.2 19.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 95.2 0.3 0.0 0.1 0.1 0.0 28.4 4.0 4.5 18.5 11.5 0.2 15.8 62.6 87.5 55.4 102.5 39.0 30.3 30.5 44.8 47.5 31.8 30.0 38.3 199.1 45.0 129.4 113.8 30.7 76.2 4.9 4.5 4.4 8.5 4.7 5.6 8.8 7.4 7.8 6.7 9.7 9.1 1.1 3.2 8.4 0.0 37.0 2.4 0.8 0.0 0.6 0.1 0.7 1.5 2.0 0.0 1.8 0.0 0.0 0.5 117.5 0.1 0.0 0.0 0.4 0.1 0.2 2.5 0.0 2.5 0.2 0.2 0.6 1.9 2.0 0.1 57.0 0.0 2.2 1.1 76.8 0.0 0.2 0.2 0.0 71.5 87.5 0.9 0.6 55.0 7.2 24.4 42.7 0.0 120.5 0.5 0.0 0.8 0.0 0.0 25.1 0.3 0.0 0.8 0.0 0.1 0.0 0.9 1.0 0.0 0.2 0.3 2.3 1.0 43.9 0.0 0.2 0.5 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DAB2 DOC-2 ENSG00000153071 "DAB adaptor protein 2" P98082 5 39371675-39462300 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Endocytosis, Protein transport, Transport, Wnt signaling pathway" "Developmental protein" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 179.1;placenta: 226.6" "Group enriched" "Detected in many" 5 "Hofbauer cells: 1756.4;Proximal tubular cells: 1653.7;Syncytiotrophoblasts: 1324.5" "Cancer enhanced" "Detected in all" "renal cancer: 52.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 8 "plasmacytoid DC: 48.7" "Lineage enriched" "Detected in many" 8 "dendritic cells: 48.7" "Cell line enhanced" "Detected in many" "ASC diff: 220.1;ASC TERT1: 234.5;fHDF/TERT166: 356.8;TIME: 211.1;U-138 MG: 237.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009314, HPA028888" Enhanced Enhanced "Nucleoli fibrillar center,Vesicles,Plasma membrane" NA NA 130000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "Nucleoli fibrillar center" "CAB009314: AB_638976, HPA028888: AB_2672814" "unprognostic (1.24e-1)" "unprognostic (7.28e-2)" "unprognostic (2.16e-1)" "unprognostic (1.25e-1)" "unprognostic (5.37e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.38e-6)" "unprognostic (3.11e-1)" "unprognostic (2.82e-1)" "unprognostic (2.78e-2)" "unprognostic (1.50e-1)" "unprognostic (1.87e-1)" "unprognostic (3.16e-2)" "prognostic unfavorable (9.67e-4)" "unprognostic (1.27e-2)" "unprognostic (2.24e-1)" "unprognostic (1.20e-1)" 76.9 113.6 7.3 33.1 8.3 4.1 48.2 13.4 13.1 48.4 26.2 33.2 13.5 32.5 116.8 16.8 21.6 50.1 20.0 7.5 7.7 179.1 27.3 53.3 33.2 14.6 10.0 34.0 22.8 10.1 7.9 226.6 12.6 13.0 54.5 11.6 24.2 19.8 11.4 21.2 25.6 47.8 7.8 58.5 16.6 10.6 20.1 20.9 23.5 16.4 19.0 44.6 20.6 10.8 0.2 8.3 12.9 27.9 220.1 234.5 16.0 145.7 149.5 56.3 92.5 108.1 0.5 0.1 8.8 356.8 54.8 0.3 2.0 5.2 78.9 0.2 4.2 19.9 191.1 35.5 52.4 0.2 24.3 146.5 0.2 91.7 16.5 87.2 172.4 9.9 0.0 5.0 95.2 0.6 2.1 0.3 8.9 4.1 15.8 5.4 32.7 0.0 37.8 3.2 0.1 0.4 17.4 9.3 79.2 20.4 0.6 4.9 211.1 237.9 26.1 27.7 11.9 0.2 0.1 0.3 82.6 18.1 31.5 5.8 2.3 0.5 2.1 4.6 0.1 0.1 0.3 1.4 6.3 0.2 0.2 1.7 3.2 1.7 1.3 48.7 0.4 12.7 7.3 8.3 13.4 13.1 7.5 7.7 14.6 10.0 12.6 7.8 20.1 10.8 100.2 38.5 42.2 0.0 14.5 14.5 1.2 15.3 3.4 1.1 38.3 26.7 55.1 70.1 9.9 95.6 70.9 170.8 83.8 29.6 197.6 75.7 1.4 31.7 161.0 116.9 9.7 10.1 11.0 2.0 20.1 139.5 3.6 36.4 25.3 50.6 187.4 3.7 1756.4 8.4 2.8 7.6 2.0 175.2 77.9 4.5 122.4 287.4 12.4 92.8 10.9 81.5 63.8 27.2 0.3 6.5 10.2 64.3 1.4 7.0 33.8 1653.7 7.5 3.5 6.6 62.4 50.4 0.5 4.8 3.5 13.4 1324.5 13.4 104.8 27.5 1.3 DAG1 "156DAG, A3a, AGRNR, DAG" ENSG00000173402 "Dystroglycan 1" Q14118 3 49468703-49535618 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Congenital muscular dystrophy, Disease variant, Dystroglycanopathy, Limb-girdle muscular dystrophy, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Granulosa cells: 207.9;Skeletal myocytes: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 280.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001960, CAB016353, HPA070563" Enhanced Supported "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 84000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "CAB001960: , CAB016353: AB_627292, HPA070563: " "unprognostic (1.58e-1)" "unprognostic (5.14e-1)" "unprognostic (6.71e-3)" "unprognostic (3.32e-1)" "unprognostic (7.39e-2)" "unprognostic (9.91e-2)" "unprognostic (1.67e-1)" "unprognostic (3.27e-2)" "unprognostic (8.18e-2)" "unprognostic (3.91e-2)" "unprognostic (5.70e-3)" "unprognostic (1.10e-1)" "prognostic favorable (2.59e-4)" "unprognostic (9.22e-2)" "unprognostic (1.99e-2)" "unprognostic (7.43e-2)" "unprognostic (1.57e-2)" 25.2 22.0 31.5 17.9 32.6 5.4 26.6 30.7 30.7 26.2 25.5 38.8 24.0 32.1 16.2 28.3 31.8 26.4 68.9 30.1 28.9 28.1 43.0 31.8 9.4 33.3 31.4 24.6 51.4 44.3 18.6 77.0 28.6 29.5 30.6 9.8 31.8 37.9 93.8 28.5 24.0 45.9 30.2 12.6 32.0 26.9 34.1 10.5 25.5 95.7 14.3 27.8 22.0 31.2 92.3 92.4 61.9 152.3 80.3 38.8 280.9 63.9 93.7 108.0 69.0 74.2 96.0 13.0 62.2 103.2 87.6 168.4 55.6 81.2 67.2 12.7 18.6 9.6 84.3 87.2 35.5 11.2 17.4 33.3 72.5 100.3 33.3 96.7 97.1 15.3 14.5 9.8 31.2 75.5 10.1 8.1 66.4 110.0 31.2 5.5 60.5 22.3 82.5 126.4 21.8 45.2 74.8 206.0 105.5 170.3 171.6 22.8 51.8 39.1 63.9 76.0 91.4 11.0 24.2 8.1 50.4 12.6 245.9 2.3 1.2 0.7 1.1 1.3 1.2 1.2 0.9 0.9 0.7 1.0 1.0 1.0 2.2 1.1 2.5 1.3 0.7 1.4 31.5 32.6 30.7 30.7 30.1 28.9 33.3 31.4 28.6 30.2 34.1 31.2 19.0 54.5 18.4 32.0 4.0 14.3 8.0 31.7 17.1 7.4 36.1 46.4 56.6 30.0 20.6 35.0 4.2 116.4 5.8 37.3 1.9 32.4 30.0 30.2 17.3 20.9 33.0 14.3 15.6 79.6 118.4 26.1 37.8 37.9 7.0 207.9 16.8 59.9 21.2 3.3 16.5 29.7 14.2 8.6 7.0 20.0 21.5 6.3 33.8 9.4 5.6 27.1 5.2 19.6 10.7 57.2 21.4 36.9 5.1 14.4 18.9 7.6 23.2 8.7 46.0 326.1 36.2 7.1 19.9 19.0 17.0 95.9 5.9 10.0 29.2 10.2 DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA069377: AB_2686132" "unprognostic (2.39e-1)" "unprognostic (4.61e-2)" "unprognostic (2.13e-3)" "unprognostic (1.42e-1)" "unprognostic (9.04e-3)" "unprognostic (3.68e-2)" "unprognostic (1.78e-3)" "unprognostic (2.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (7.18e-5)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (2.18e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.81e-2)" 7.3 15.6 9.9 6.7 9.9 15.0 6.6 7.3 11.1 7.0 5.9 6.7 7.6 5.8 3.6 8.0 5.9 6.4 5.6 11.2 8.8 4.9 7.9 9.3 7.4 9.7 7.7 7.9 6.9 7.0 4.3 8.7 8.0 5.3 5.0 3.4 7.7 4.5 13.3 12.4 7.6 5.8 8.4 8.5 7.1 5.5 8.1 8.1 7.5 7.0 6.7 5.8 7.3 10.7 21.6 23.9 10.9 14.3 16.1 12.5 8.4 29.8 21.3 26.6 28.7 13.6 24.4 12.3 12.5 15.4 64.8 32.4 17.8 16.7 15.2 5.8 11.7 6.6 26.9 9.4 17.3 18.8 10.1 11.3 27.2 17.9 17.5 10.7 11.7 15.6 18.2 6.1 15.9 16.2 6.7 26.9 39.6 11.3 18.5 57.4 12.7 25.5 16.8 8.1 13.5 8.4 17.7 26.7 5.3 17.2 19.0 34.7 14.4 22.4 41.9 28.1 13.9 6.2 11.2 10.4 11.3 28.9 28.2 10.8 22.8 22.0 6.2 21.3 5.5 8.2 4.8 4.1 28.6 4.7 11.4 6.7 10.2 3.9 19.5 5.0 4.3 12.2 9.9 9.9 7.3 11.1 11.2 8.8 9.7 7.7 8.0 8.4 8.1 10.7 6.5 9.6 12.6 5.9 7.9 16.8 3.6 6.2 12.0 4.5 5.7 5.7 3.1 4.3 5.0 5.5 2.1 5.1 4.8 12.2 0.0 7.0 0.4 10.3 6.8 9.0 2.4 13.3 13.8 6.2 8.9 5.4 19.4 19.9 3.8 5.5 8.9 8.0 17.2 0.0 9.2 5.8 6.1 16.1 17.4 1.7 6.2 16.3 5.4 26.2 15.8 1.4 7.2 2.5 6.5 12.2 8.0 2.2 5.0 5.7 10.6 1.6 3.8 4.3 0.0 4.0 5.0 8.5 7.1 9.4 13.4 12.4 6.7 7.4 7.6 4.3 DAW1 "FLJ25955, ODA16, WDR69" ENSG00000123977 "Dynein assembly factor with WD repeats 1" Q8N136 2 227871054-227924344 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "choroid plexus: 25.7;fallopian tube: 32.6;testis: 51.3" "Group enriched" "Detected in some" 13 "Early spermatids: 106.7;Late spermatids: 215.3;Respiratory ciliated cells: 113.9;Spermatocytes: 177.1" "Cancer enhanced" "Detected in some" "lung cancer: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 8.8;HUVEC TERT2: 21.8;U-2197: 40.7" "Low region specificity" "Detected in many" HPA046118 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Nuclear bodies, Plasma membrane" "HPA046118: AB_10961428" "unprognostic (1.23e-1)" "unprognostic (1.42e-1)" "unprognostic (1.95e-1)" "unprognostic (1.66e-1)" "unprognostic (4.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.63e-3)" "unprognostic (2.90e-2)" "unprognostic (9.92e-3)" "unprognostic (1.54e-5)" "unprognostic (1.52e-1)" "unprognostic (6.83e-3)" "unprognostic (1.70e-1)" "unprognostic (3.08e-1)" 0.6 0.0 4.3 0.1 5.3 0.3 0.4 2.9 4.7 0.7 25.7 0.2 0.0 0.1 0.3 0.5 32.6 0.3 0.5 4.5 4.5 0.2 0.4 3.0 0.2 7.3 8.8 0.1 0.0 0.2 0.2 0.8 5.5 0.0 0.0 0.7 0.1 0.0 3.6 0.2 0.0 0.1 6.8 0.2 0.1 51.3 5.4 0.4 0.1 0.0 0.2 0.1 0.0 5.4 0.8 0.0 0.1 0.0 0.3 1.2 0.6 0.8 0.4 0.9 0.6 5.4 0.5 0.2 0.0 0.2 8.8 0.1 0.0 0.2 2.1 0.0 0.0 0.0 0.4 0.0 1.1 0.0 0.1 1.7 0.0 1.0 0.7 5.8 21.8 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.5 0.0 0.2 0.0 0.1 0.3 0.1 0.2 0.4 0.1 0.8 0.0 0.0 0.2 0.0 0.5 2.2 0.2 2.0 40.7 0.0 0.0 0.1 0.3 3.9 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.3 2.9 4.7 4.5 4.5 7.3 8.8 5.5 6.8 5.4 5.4 0.0 0.0 1.1 0.3 0.0 0.0 0.0 9.6 0.0 0.0 0.0 0.0 0.7 0.0 11.5 0.0 4.2 0.2 0.0 0.0 0.0 0.2 106.7 11.2 0.0 0.2 0.0 0.0 6.2 0.0 2.8 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 8.2 0.0 0.0 215.3 3.4 0.3 0.0 0.0 0.0 0.2 0.0 0.5 0.1 3.0 0.2 2.6 0.0 0.1 0.0 0.1 113.9 0.3 0.0 0.7 2.1 177.1 4.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DCAF13 "DKFZP564O0463, Gm83, HSPC064, Sof1, WDSOF1" ENSG00000164934 "DDB1 and CUL4 associated factor 13" Q9NV06 8 103414714-103443453 "Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing, Ubl conjugation pathway" Ribonucleoprotein "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044504 Uncertain Supported "Nucleoplasm,Nucleoli,Cell Junctions,Centrosome,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 23: Testis - Cell cycle regulation" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Centrosome, Cytosol" "HPA044504: AB_2678963" "prognostic unfavorable (4.06e-4)" "unprognostic (4.39e-2)" "unprognostic (1.70e-1)" "unprognostic (4.46e-3)" "unprognostic (3.57e-2)" "unprognostic (7.86e-3)" "prognostic unfavorable (8.05e-6)" "unprognostic (5.92e-3)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.54e-3)" "unprognostic (2.31e-2)" "prognostic unfavorable (2.85e-4)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (6.42e-2)" "unprognostic (8.63e-2)" 16.7 19.2 10.3 22.9 11.0 15.2 23.9 11.3 15.6 17.7 12.8 20.7 16.1 16.2 19.1 21.3 18.0 12.7 16.2 10.9 11.1 32.4 20.7 12.9 24.7 10.8 13.7 13.6 18.5 20.0 15.6 18.7 11.4 14.7 21.4 13.8 14.3 12.8 18.8 15.7 14.5 18.2 11.3 14.3 15.6 32.2 10.4 24.7 18.1 16.0 30.5 33.6 14.6 11.9 96.5 84.2 76.9 79.0 54.7 62.7 57.6 70.1 53.2 64.4 65.9 83.1 90.9 132.2 116.1 73.3 64.0 69.9 105.8 89.0 124.1 127.7 74.9 183.0 48.0 95.9 62.2 76.1 75.7 51.8 59.9 95.9 157.5 40.3 91.4 89.6 125.3 56.7 99.9 78.0 144.9 79.3 118.0 268.9 129.6 92.6 93.3 136.4 95.3 78.6 97.6 92.3 43.5 67.3 83.1 67.4 103.9 51.2 60.6 65.3 105.3 85.5 94.7 61.7 116.5 188.0 88.0 162.8 85.7 19.6 37.6 22.1 35.5 46.5 48.8 60.8 37.5 38.2 54.4 50.8 37.0 38.2 4.2 52.8 35.2 28.3 58.0 44.9 10.3 11.0 11.3 15.6 10.9 11.1 10.8 13.7 11.4 11.3 10.4 11.9 40.0 16.0 17.0 9.1 39.7 79.5 76.6 92.4 38.1 19.6 21.6 24.9 20.8 12.8 53.8 33.1 25.0 57.9 34.8 11.0 39.2 55.0 54.6 26.9 35.4 39.9 14.5 22.1 9.5 48.4 75.0 37.4 17.9 24.7 40.6 49.3 17.5 16.9 42.7 16.8 9.0 17.5 69.2 14.8 23.9 16.7 24.2 22.9 26.6 11.2 28.5 28.8 27.8 16.1 20.0 43.6 12.3 17.7 30.3 51.1 24.3 79.1 36.0 23.7 13.1 50.2 48.0 102.0 86.3 37.1 77.0 33.9 33.1 41.7 28.1 56.9 DCAF16 "C4orf30, FLJ20280" ENSG00000163257 "DDB1 and CUL4 associated factor 16" Q9NXF7 4 17800655-17810758 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042487 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042487: AB_10795505" "unprognostic (2.23e-3)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (8.02e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.40e-4)" "prognostic favorable (5.78e-4)" "unprognostic (5.31e-2)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" "unprognostic (3.19e-2)" "unprognostic (1.78e-1)" "unprognostic (8.72e-2)" "unprognostic (1.68e-1)" "unprognostic (2.23e-3)" "prognostic favorable (7.67e-4)" 9.6 8.2 4.5 8.0 7.0 18.1 13.0 6.4 6.7 12.8 2.9 10.4 7.9 13.8 10.2 7.9 11.9 6.6 8.4 4.2 7.4 9.2 4.8 9.1 11.9 6.1 5.8 19.4 11.3 12.3 13.3 9.8 5.7 10.6 9.5 13.3 10.9 7.9 8.2 15.0 10.2 8.9 4.5 8.9 8.8 10.9 7.8 12.0 10.1 4.4 11.4 10.0 10.2 9.4 21.7 4.6 24.3 25.5 6.8 11.9 13.2 13.9 16.3 16.2 19.1 13.1 17.2 24.2 10.8 12.9 13.1 10.7 14.4 14.7 23.9 8.3 13.2 34.2 16.0 21.5 16.3 30.4 13.4 15.5 11.8 20.6 20.3 10.8 11.3 23.6 37.4 39.3 9.4 8.2 33.4 29.0 20.0 6.3 13.1 35.0 27.8 15.7 7.1 16.9 36.0 28.9 14.8 3.9 16.9 12.2 14.3 8.1 14.5 18.7 14.7 20.8 17.8 17.3 7.4 29.4 15.4 20.6 12.8 7.8 1.4 2.1 2.5 1.6 3.3 2.0 2.7 2.8 0.9 2.9 3.4 3.2 1.0 2.1 1.1 1.8 2.1 1.3 4.5 7.0 6.4 6.7 4.2 7.4 6.1 5.8 5.7 4.5 7.8 9.4 11.6 19.2 24.8 13.1 17.6 25.4 24.3 9.4 25.6 12.2 16.3 16.9 21.9 12.8 14.4 9.2 6.2 17.6 27.0 8.6 13.7 9.9 19.6 12.9 18.4 13.0 17.5 21.7 20.2 7.7 10.0 15.9 14.3 13.3 17.1 24.8 11.4 6.4 7.7 15.2 20.2 12.5 14.2 11.9 11.3 11.5 21.1 9.4 10.6 15.0 10.2 27.5 7.2 29.1 36.7 11.8 7.6 22.2 27.6 14.6 9.2 5.1 17.1 14.6 13.1 21.7 16.2 28.8 17.3 19.5 21.2 12.3 20.3 19.0 13.9 19.2 DCBLD2 "CLCP1, ESDN" ENSG00000057019 "Discoidin, CUB and LCCL domain containing 2" Q96PD2 3 98795941-98901695 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 83.8;Oligodendrocyte precursor cells: 88.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 455.0;hTERT-RPE1: 648.9;LHCN-M2: 776.8;RPTEC TERT1: 479.0;U-87 MG: 581.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016909 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 2200000 "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA016909: AB_1847510" "unprognostic (1.66e-1)" "unprognostic (1.45e-1)" "unprognostic (4.46e-2)" "unprognostic (2.64e-1)" "unprognostic (5.97e-3)" "unprognostic (9.29e-3)" "unprognostic (8.31e-3)" "unprognostic (1.06e-3)" "unprognostic (1.42e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (1.52e-4)" "unprognostic (2.43e-1)" "prognostic unfavorable (3.32e-5)" "prognostic unfavorable (2.87e-4)" "unprognostic (7.76e-2)" "unprognostic (3.93e-2)" "unprognostic (1.59e-3)" 12.2 13.3 4.0 4.5 3.8 1.2 8.2 8.1 5.8 8.3 6.6 11.5 2.8 14.6 8.0 6.4 14.5 12.5 27.6 3.4 5.9 11.0 9.8 11.5 3.6 6.5 6.9 17.8 5.8 13.2 6.6 8.0 26.7 11.5 7.0 22.4 10.1 14.9 5.2 8.3 4.1 16.3 4.8 1.6 6.5 23.8 7.3 6.9 15.7 8.4 3.9 7.8 5.1 5.0 55.3 397.0 52.3 41.2 67.8 160.1 22.7 122.0 57.9 81.4 91.9 33.9 171.6 0.1 373.7 211.5 249.0 50.3 24.1 198.8 186.2 0.8 8.4 19.4 12.1 51.5 41.6 9.3 8.7 63.8 30.3 234.3 455.0 648.9 54.6 7.1 4.0 5.0 776.8 14.6 7.7 5.5 36.5 0.4 135.6 8.1 98.2 4.8 479.0 14.4 14.0 24.3 33.5 6.9 145.9 35.2 26.4 7.3 90.4 208.0 166.6 53.8 433.0 6.3 9.7 7.4 581.3 3.4 92.8 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.0 3.8 8.1 5.8 3.4 5.9 6.5 6.9 26.7 4.8 7.3 5.0 5.9 32.1 52.8 18.3 2.7 22.8 15.5 18.2 17.1 12.9 15.5 16.3 83.8 17.2 19.0 18.4 77.2 12.4 1.6 4.3 0.0 30.5 3.1 32.2 39.5 7.7 3.6 5.9 51.6 8.0 9.7 33.8 6.1 38.3 38.0 52.2 6.8 20.5 4.0 13.5 51.3 8.0 20.3 3.2 6.2 5.8 22.1 4.0 8.8 25.3 1.4 40.9 2.1 88.4 38.9 26.3 4.6 50.4 1.6 11.9 0.7 7.9 22.8 48.9 0.0 12.3 31.3 15.8 24.2 14.1 15.6 4.0 1.8 34.4 8.2 7.1 DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.8;Endometrial stromal cells: 17.3;Endothelial cells: 29.0;Fibroblasts: 17.0;Granulosa cells: 19.3;Hepatic stellate cells: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 33.5;HUVEC TERT2: 47.1;REH: 23.5;SH-SY5Y: 32.4;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" 9.4 2.5 7.4 8.4 6.8 0.7 9.3 6.1 6.3 19.5 0.9 19.0 4.1 28.9 2.4 5.0 13.2 8.3 9.2 6.6 10.1 4.6 2.0 10.1 4.0 7.6 6.3 11.6 3.3 2.0 3.2 10.1 5.7 9.3 3.4 0.6 3.5 11.5 4.2 3.7 8.3 16.2 4.7 12.9 8.2 3.0 8.7 3.8 4.1 4.6 2.2 14.8 9.3 3.8 0.0 0.1 33.5 0.1 0.0 0.1 0.3 1.2 8.7 5.4 6.0 0.3 0.0 0.1 5.1 9.9 0.4 0.0 2.7 0.1 3.7 0.1 0.9 0.7 0.0 0.0 0.3 0.2 0.0 1.0 0.1 2.5 0.0 0.0 47.1 0.1 0.2 0.0 2.0 0.0 1.2 0.6 5.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 2.4 32.4 0.0 0.3 0.2 3.5 0.0 1.3 20.4 0.1 10.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 7.4 6.8 6.1 6.3 6.6 10.1 7.6 6.3 5.7 4.7 8.7 3.8 34.8 0.0 0.5 12.1 0.2 2.9 0.3 0.0 0.0 1.5 1.7 3.0 3.8 4.3 0.0 0.0 0.0 0.2 1.4 0.2 0.0 1.0 3.1 0.8 17.3 29.0 0.0 2.7 2.0 0.4 0.3 17.0 1.1 0.7 0.0 19.3 61.1 0.2 2.2 0.0 7.4 0.7 0.0 4.7 4.2 3.4 1.2 2.4 16.0 4.7 0.2 0.9 0.0 10.1 1.4 0.1 0.1 1.9 0.2 0.3 0.1 0.1 0.0 0.5 0.0 7.4 4.9 4.9 0.6 0.5 1.7 0.3 1.2 4.6 1.1 0.1 DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 63.0;Early spermatids: 20.7;Excitatory neurons: 30.3;Horizontal cells: 25.2;Inhibitory neurons: 13.2;Late spermatids: 19.4;Microglial cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "U-2 OS: 4.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" 0.0 0.1 0.6 0.0 0.8 0.0 0.1 0.3 0.5 0.9 0.0 1.7 0.0 1.4 0.0 0.0 0.9 0.1 0.0 0.4 0.8 0.1 0.0 0.1 0.0 0.5 1.3 0.7 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.7 0.0 1.2 1.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.3 0.5 0.4 0.8 0.5 1.3 0.3 0.7 1.1 1.4 0.0 0.0 0.0 63.0 0.0 0.4 0.2 0.8 0.0 0.4 0.8 0.6 1.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.7 0.1 0.5 0.3 6.7 0.0 30.3 0.0 0.0 1.8 3.6 0.0 0.0 1.2 0.0 0.0 0.1 25.2 13.2 0.1 0.0 0.0 0.7 19.4 0.6 0.0 0.0 13.1 0.0 0.2 0.0 6.6 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.9 0.2 0.0 0.3 0.5 1.7 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 DCP2 NUDT20 ENSG00000172795 "Decapping mRNA 2" Q8IU60 5 112976702-113022195 "Enzymes, Predicted intracellular proteins" "Nonsense-mediated mRNA decay" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB011677, HPA057676" Approved Approved "Nucleoplasm,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytoplasmic bodies" "Cell Junctions" "CAB011677: AB_731858, HPA057676: AB_2683500" "unprognostic (2.76e-1)" "unprognostic (3.27e-1)" "unprognostic (2.79e-1)" "unprognostic (3.09e-1)" "unprognostic (1.28e-1)" "unprognostic (3.86e-3)" "prognostic unfavorable (4.84e-4)" "unprognostic (1.87e-1)" "unprognostic (3.64e-2)" "unprognostic (6.26e-2)" "unprognostic (1.15e-1)" "unprognostic (9.30e-2)" "prognostic unfavorable (2.66e-5)" "unprognostic (8.39e-2)" "unprognostic (2.84e-1)" "unprognostic (3.25e-2)" "unprognostic (5.75e-2)" 4.6 4.0 5.9 8.1 6.0 14.0 6.9 9.8 5.7 6.0 6.6 3.9 3.7 4.3 3.4 4.1 4.7 3.5 3.4 5.9 7.2 4.8 4.7 6.9 12.6 5.5 4.9 6.7 3.3 3.1 3.7 12.1 5.8 4.4 4.1 7.4 5.3 3.5 4.8 5.8 5.1 3.3 4.5 10.2 4.0 3.8 8.5 17.9 3.7 3.9 12.3 4.4 5.2 5.1 6.4 5.6 24.1 19.0 4.5 5.3 37.0 6.7 4.3 7.2 9.8 25.0 13.1 32.2 8.5 3.2 5.6 7.9 27.6 7.1 8.8 9.0 11.0 29.5 4.6 9.9 5.4 20.1 15.3 4.8 5.3 8.4 9.0 6.9 12.5 24.8 22.7 12.0 6.1 8.1 29.6 19.6 20.8 4.0 2.9 27.0 22.7 12.2 10.5 15.4 5.6 11.4 8.3 8.8 11.3 24.1 25.3 24.4 7.7 7.8 13.9 4.4 8.8 8.8 19.8 23.6 4.7 26.0 6.3 14.0 4.9 3.7 3.0 6.1 4.2 3.8 3.7 3.0 5.1 2.5 3.4 3.7 9.4 3.5 7.3 2.9 4.3 2.6 5.9 6.0 9.8 5.7 5.9 7.2 5.5 4.9 5.8 4.5 8.5 5.1 30.0 19.2 16.8 16.0 50.7 27.8 19.9 22.3 31.9 24.7 43.5 26.4 12.4 8.6 24.1 20.2 79.2 66.7 65.0 11.6 19.6 11.2 24.3 21.7 38.1 28.9 16.2 41.9 25.5 11.8 49.6 25.7 17.3 25.7 19.6 66.7 28.5 7.0 31.7 28.6 34.1 8.9 20.3 78.1 41.5 53.8 19.0 57.4 26.6 56.2 90.7 36.9 35.0 26.7 28.8 17.3 10.6 10.9 27.1 33.3 13.8 14.4 22.7 34.6 6.6 16.5 32.3 36.6 29.5 20.0 26.6 64.4 50.1 52.0 13.1 48.8 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCTN6 WS-3 ENSG00000104671 "Dynactin subunit 6" O00399 8 30156319-30183639 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024049, HPA024558" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoli, Cytosol" "Plasma membrane" "HPA024049: AB_1847524, HPA024558: AB_1847525" "unprognostic (1.28e-1)" "unprognostic (8.32e-3)" "unprognostic (1.65e-2)" "unprognostic (1.88e-1)" "unprognostic (1.69e-1)" "unprognostic (7.50e-2)" "prognostic unfavorable (5.51e-4)" "unprognostic (1.26e-1)" "unprognostic (7.84e-2)" "unprognostic (1.08e-2)" "unprognostic (2.38e-2)" "unprognostic (9.26e-2)" "prognostic favorable (5.42e-4)" "unprognostic (1.06e-1)" "unprognostic (3.10e-1)" "unprognostic (7.54e-2)" "unprognostic (1.43e-1)" 50.6 54.1 48.0 26.6 51.1 43.7 53.0 51.8 74.1 32.3 42.3 37.5 23.8 38.2 43.5 34.3 30.1 32.8 75.6 50.4 54.8 54.2 46.7 34.0 28.3 50.8 49.8 41.5 32.0 72.8 29.7 53.6 51.1 34.7 36.2 42.4 33.6 36.7 36.6 29.0 26.1 42.6 52.9 27.6 31.9 21.9 50.5 37.8 54.6 43.5 31.2 45.8 31.6 58.6 53.6 51.9 64.4 33.8 59.3 80.7 42.1 72.8 87.0 70.4 74.9 33.6 35.8 41.0 76.0 78.8 64.9 39.6 46.1 64.2 83.8 32.4 34.3 57.8 40.9 54.5 45.8 33.6 47.4 68.2 90.4 51.2 54.8 61.5 65.2 58.0 66.4 44.3 77.0 41.7 62.4 53.0 51.6 93.8 32.0 32.4 48.7 35.3 104.6 54.1 105.4 60.0 42.7 53.0 77.9 32.4 50.4 48.3 60.8 37.4 128.9 31.9 52.4 18.1 22.2 51.8 69.7 38.1 68.1 16.7 13.5 5.0 8.1 15.8 9.1 7.1 7.5 9.8 15.9 5.3 9.5 11.4 3.7 11.2 15.9 20.8 8.1 6.8 48.0 51.1 51.8 74.1 50.4 54.8 50.8 49.8 51.1 52.9 50.5 58.6 61.3 25.6 39.7 19.9 34.9 57.2 91.3 127.1 25.6 36.4 45.4 43.2 83.4 47.1 85.3 44.1 14.6 88.5 48.9 28.1 123.3 94.5 18.0 32.5 37.2 58.7 40.8 28.2 19.0 84.5 87.7 56.6 25.0 39.6 46.9 44.0 45.7 42.7 71.4 26.9 17.3 31.6 91.6 43.9 54.8 12.5 80.8 43.2 69.4 15.0 58.4 63.3 17.5 17.6 21.3 91.1 43.1 75.2 32.3 48.8 36.3 147.1 71.6 40.3 52.6 63.1 66.0 44.2 47.3 38.0 63.5 203.6 59.8 49.5 33.0 95.0 DCUN1D2 "C13orf17, FLJ10704, FLJ20092" ENSG00000150401 "Defective in cullin neddylation 1 domain containing 2" Q6PH85 13 113455819-113490951 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.6;skeletal muscle: 108.7;tongue: 69.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.6;Excitatory neurons: 43.9;Inhibitory neurons: 37.9;Oligodendrocytes: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 11.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 11.3" "Cell line enhanced" "Detected in all" "SCLC-21H: 54.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039349 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039349: AB_10673240" "unprognostic (3.09e-1)" "unprognostic (1.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (7.43e-2)" "unprognostic (7.68e-2)" "unprognostic (4.33e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (2.02e-2)" "prognostic favorable (5.65e-5)" "unprognostic (1.21e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.69e-2)" "unprognostic (1.25e-2)" 8.1 8.4 9.7 4.4 8.8 14.0 7.6 23.4 14.6 8.9 30.1 9.2 4.6 9.4 9.4 6.4 7.7 5.4 98.6 8.5 9.7 8.3 8.5 7.7 7.2 12.6 9.9 8.1 7.1 5.9 10.5 7.4 13.4 7.5 6.4 16.8 9.0 4.8 108.7 14.4 8.3 7.4 8.5 9.4 8.3 9.0 10.2 8.1 4.5 69.1 7.3 7.0 7.4 15.3 13.3 7.5 13.0 9.5 9.8 8.3 10.6 10.0 11.4 9.0 10.8 27.4 7.3 9.8 3.4 11.3 13.9 17.2 13.8 7.1 12.5 6.7 23.4 15.6 40.9 7.5 6.0 24.5 11.2 12.0 11.6 9.8 9.0 6.2 8.3 12.9 9.2 8.4 8.6 9.0 16.6 38.1 8.9 9.7 11.8 16.9 20.8 11.2 6.4 8.3 54.7 12.2 6.9 24.6 7.0 8.8 14.1 10.6 12.7 11.3 16.4 9.0 14.3 25.5 11.4 19.2 25.3 10.4 7.7 11.3 1.5 2.2 2.0 1.0 2.5 1.9 1.8 1.4 1.6 0.9 1.8 0.9 0.8 1.9 1.5 0.2 2.0 1.5 9.7 8.8 23.4 14.6 8.5 9.7 12.6 9.9 13.4 8.5 10.2 15.3 7.6 16.0 15.6 27.4 2.4 5.9 2.0 2.3 1.8 9.0 6.7 4.3 79.6 0.0 8.4 3.7 16.7 2.4 2.5 4.8 1.9 1.7 5.9 5.0 6.5 7.1 6.6 3.0 43.9 1.3 1.4 6.6 8.2 6.0 5.1 4.6 5.7 3.9 1.4 18.5 37.9 4.4 0.0 3.5 4.4 8.3 7.2 4.2 5.4 18.7 2.2 4.8 3.1 30.2 42.8 2.1 1.3 5.7 2.0 3.7 3.4 2.5 4.6 9.6 0.0 3.5 3.7 3.8 4.2 4.3 7.4 2.6 3.5 5.2 3.9 3.2 DDAH1 DDAH ENSG00000153904 "Dimethylarginine dimethylaminohydrolase 1" O94760 1 85318481-85578363 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 131.8;kidney: 124.8" "Cell type enhanced" "Detected in many" "Astrocytes: 364.4;Excitatory neurons: 197.4;Oligodendrocyte precursor cells: 182.4;Proximal tubular cells: 283.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 239.4;LHCN-M2: 179.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006308, HPA071064" Enhanced Approved "Nucleoli,Plasma membrane,Cytosol" NA NA 350000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoli "HPA006308: AB_1847532, HPA071064: " "unprognostic (1.44e-2)" "unprognostic (2.43e-1)" "prognostic favorable (5.99e-4)" "unprognostic (6.82e-2)" "unprognostic (1.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.55e-1)" "unprognostic (3.85e-2)" "unprognostic (2.57e-1)" "unprognostic (1.02e-2)" "unprognostic (3.62e-2)" "unprognostic (1.56e-1)" "prognostic favorable (5.21e-6)" "unprognostic (5.37e-2)" "unprognostic (9.06e-2)" "unprognostic (5.81e-2)" "unprognostic (1.56e-2)" 10.3 28.6 95.9 12.8 100.9 0.6 18.8 61.5 131.8 22.4 73.4 45.1 40.1 10.8 76.5 12.6 36.5 25.5 17.4 102.0 77.3 124.8 79.5 26.4 2.6 58.6 84.8 2.9 27.5 21.1 6.3 11.6 62.6 28.5 45.3 34.6 17.7 18.6 30.4 5.6 39.7 16.5 59.5 10.6 29.7 19.1 106.6 1.0 28.9 14.0 2.0 19.2 2.6 80.3 63.1 7.6 36.0 6.9 84.1 78.0 9.2 155.9 120.0 63.6 75.6 89.9 16.5 0.1 39.2 239.4 38.3 17.8 79.7 15.0 93.0 0.3 29.5 0.2 22.3 31.8 40.9 57.6 3.2 60.5 2.0 50.4 24.9 85.5 75.9 0.0 0.1 6.0 179.7 7.5 3.0 0.3 25.5 124.6 22.6 0.0 63.1 0.9 113.4 46.3 59.2 115.0 18.0 56.3 9.1 38.7 29.6 4.9 107.7 31.6 27.0 11.7 57.8 0.0 0.1 0.2 1.6 0.1 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 95.9 100.9 61.5 131.8 102.0 77.3 58.6 84.8 62.6 59.5 106.6 80.3 14.1 35.3 43.4 364.4 2.6 13.8 4.6 6.8 5.7 4.5 31.2 13.8 11.8 61.5 13.6 69.9 4.2 2.7 0.4 75.3 125.2 15.9 22.5 36.9 9.8 7.5 34.2 2.7 197.4 31.2 0.9 13.9 47.9 24.2 0.0 59.3 8.2 102.8 1.1 0.0 51.0 86.9 8.2 2.2 5.5 25.6 15.8 2.4 12.4 23.4 0.6 68.4 0.0 182.4 9.6 44.5 69.4 74.9 0.0 33.6 68.7 283.3 36.5 9.4 13.1 15.3 18.6 4.6 5.4 32.6 14.3 0.8 2.5 13.5 106.7 8.3 DDB2 "DDBB, FLJ34321, UV-DDB2, XPE" ENSG00000134574 "Damage specific DNA binding protein 2" Q92466 11 47214465-47239217 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 75.1;monocytes: 135.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025912, HPA058406" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Cell Junctions" "CAB025912: , HPA058406: AB_2683708" "prognostic favorable (7.29e-4)" "prognostic favorable (1.58e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.20e-4)" "unprognostic (4.29e-2)" "unprognostic (2.04e-2)" "unprognostic (2.96e-2)" "unprognostic (6.18e-2)" "unprognostic (2.25e-1)" "unprognostic (3.58e-3)" "unprognostic (3.53e-1)" "unprognostic (1.94e-1)" "unprognostic (4.57e-3)" "unprognostic (1.21e-2)" "unprognostic (4.25e-2)" "unprognostic (9.82e-3)" "unprognostic (1.07e-1)" 13.2 22.5 2.6 8.2 3.2 11.6 13.5 3.4 3.6 12.5 3.4 12.8 7.6 12.7 11.7 24.8 17.6 12.5 6.8 2.5 2.4 4.4 27.0 12.2 14.7 3.4 2.7 11.6 14.4 4.8 4.7 6.8 3.5 9.7 14.9 2.3 14.4 11.7 6.2 46.7 10.2 13.9 2.7 11.3 9.5 4.5 3.2 23.5 5.5 6.9 17.0 11.2 14.1 3.6 23.7 62.3 25.9 19.3 16.6 32.7 29.9 26.0 58.8 32.0 37.1 10.1 14.1 56.6 5.3 23.2 23.6 40.8 14.6 51.8 15.7 14.5 27.5 13.3 55.7 46.7 15.8 15.9 34.4 43.4 58.0 15.9 35.2 10.2 94.2 14.7 3.5 27.0 52.7 44.4 60.4 7.7 8.4 31.1 22.3 30.3 5.6 30.6 13.5 22.7 13.2 16.7 31.2 8.7 8.1 30.8 56.1 5.5 41.2 96.8 44.1 21.3 12.6 27.6 22.4 12.5 37.0 20.2 35.9 9.8 12.8 20.2 19.3 18.4 18.8 18.3 20.1 18.8 10.4 14.5 14.8 15.7 3.7 14.1 15.8 0.3 47.7 15.9 2.6 3.2 3.4 3.6 2.5 2.4 3.4 2.7 3.5 2.7 3.2 3.6 13.8 16.0 22.2 7.8 25.1 38.9 39.7 28.1 75.1 5.0 18.0 25.8 7.8 11.5 16.3 5.5 10.4 3.6 21.3 11.1 9.8 12.5 1.5 5.2 8.1 19.5 7.7 19.1 6.6 13.8 9.0 16.0 18.3 9.5 22.8 31.2 15.0 16.6 17.5 1.7 1.4 12.6 16.2 17.5 12.8 2.1 19.0 16.8 19.6 24.4 135.5 9.6 35.0 1.0 10.6 19.9 9.8 10.5 34.1 8.9 15.7 7.7 13.9 12.8 0.0 12.1 14.0 3.1 8.6 34.5 30.3 1.5 34.3 25.4 16.5 26.5 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DDIT4L "REDD2, Rtp801L" ENSG00000145358 "DNA damage inducible transcript 4 like" Q96D03 4 100185870-100190782 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "skeletal muscle: 323.5;tongue: 106.9" "Cell type enhanced" "Detected in many" "Collecting duct cells: 22.0;Distal tubular cells: 21.5;Extravillous trophoblasts: 18.5;Granulosa cells: 23.5;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 19.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 19.3;BJ: 29.6;fHDF/TERT166: 16.2;HSkMC: 14.7;hTERT-RPE1: 32.8;RPTEC TERT1: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050903 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA050903: " "unprognostic (2.21e-1)" "unprognostic (1.92e-1)" "unprognostic (1.34e-1)" "prognostic favorable (5.77e-4)" "unprognostic (1.66e-3)" "unprognostic (5.92e-2)" "unprognostic (2.72e-2)" "unprognostic (3.12e-1)" "unprognostic (3.21e-1)" "unprognostic (7.18e-2)" "unprognostic (2.59e-1)" "unprognostic (1.41e-1)" "unprognostic (4.47e-2)" "unprognostic (4.82e-3)" "unprognostic (2.09e-2)" "unprognostic (7.53e-5)" "unprognostic (4.99e-3)" 3.1 1.0 7.0 0.6 21.1 0.4 2.2 8.5 11.0 23.0 7.7 2.0 0.3 1.5 1.7 7.7 2.1 0.6 2.3 10.2 7.6 21.8 0.4 0.8 0.5 11.8 8.8 7.7 0.4 0.6 2.0 3.7 11.1 11.2 0.9 1.2 17.4 6.9 323.5 1.1 0.7 1.6 9.1 1.2 0.5 3.0 8.7 1.2 1.1 106.9 0.4 1.2 2.6 8.9 0.0 2.2 8.5 0.0 3.7 19.3 1.2 29.6 2.5 0.5 0.1 0.1 0.9 0.0 0.7 16.2 0.7 0.0 6.2 0.5 0.5 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 14.7 0.1 0.3 1.5 32.8 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 9.7 0.0 0.0 0.6 0.0 0.0 20.5 0.1 0.1 0.1 0.6 1.2 4.0 2.0 0.0 0.1 0.1 0.0 0.0 0.0 2.3 3.9 0.0 0.0 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.0 21.1 8.5 11.0 10.2 7.6 11.8 8.8 11.1 9.1 8.7 8.9 3.8 0.0 0.0 6.2 0.0 2.7 0.2 4.2 1.8 0.1 1.0 0.9 7.3 0.0 1.3 22.0 0.0 1.9 0.4 0.2 21.5 0.1 0.8 0.5 0.3 3.6 0.0 0.0 0.0 0.0 18.5 5.1 1.5 0.9 0.0 23.5 0.0 0.0 12.0 0.0 0.5 0.3 0.0 0.0 3.0 0.4 0.9 0.3 7.2 0.0 0.0 8.6 0.0 0.5 0.0 0.5 0.0 2.2 0.2 1.1 0.0 2.2 0.1 0.2 19.7 7.3 11.9 4.7 0.8 0.9 1.4 4.0 0.6 8.3 0.4 0.3 DDR1 "CAK, CD167, EDDR1, NEP, NTRK4, PTK3A, RTK6" ENSG00000204580 "Discoidin domain receptor tyrosine kinase 1" Q08345 6 30876421-30900156 "CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lactation, Pregnancy" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 90.9;HBEC3-KT: 70.1;RT4: 93.5;T-47d: 103.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010162, CAB025656, HPA057194" Approved Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 4400000 "Cluster 30: Non-specific - Translation" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cell Junctions" "CAB010162: AB_2092090, CAB025656: , HPA057194: " "unprognostic (2.11e-2)" "unprognostic (9.31e-2)" "unprognostic (1.01e-1)" "unprognostic (1.09e-1)" "unprognostic (2.07e-1)" "unprognostic (7.75e-3)" "unprognostic (6.43e-2)" "unprognostic (1.92e-1)" "unprognostic (1.73e-1)" "unprognostic (1.42e-1)" "unprognostic (1.50e-1)" "unprognostic (4.41e-2)" "prognostic favorable (3.31e-10)" "unprognostic (1.42e-1)" "unprognostic (2.53e-1)" "unprognostic (5.49e-3)" "unprognostic (4.09e-2)" 26.5 50.4 24.1 5.3 49.5 0.4 54.6 47.9 20.2 55.2 4.8 57.7 12.3 23.4 4.5 150.1 46.2 11.4 42.1 17.5 40.7 96.8 6.3 33.7 1.2 68.7 47.3 41.5 99.7 19.7 67.9 4.2 57.9 70.2 10.7 4.5 131.7 13.8 40.5 121.1 47.3 1.1 38.8 11.5 71.1 16.5 46.3 7.0 85.9 4.3 3.0 45.0 88.4 58.9 58.2 18.5 26.0 5.4 1.7 2.4 16.2 1.4 0.4 0.8 0.1 25.2 29.8 0.5 30.9 5.1 26.8 90.9 5.7 70.1 0.3 32.0 9.9 0.2 18.7 6.7 5.0 0.0 1.2 3.3 35.4 0.4 0.5 16.1 2.0 1.4 17.3 0.7 4.0 36.5 2.0 0.1 4.5 31.8 3.8 3.9 19.5 2.2 13.1 93.5 4.7 2.5 5.4 41.4 19.4 8.6 103.0 0.6 4.3 12.8 11.7 1.2 13.6 0.8 0.1 2.6 8.4 0.0 11.2 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.2 24.1 49.5 47.9 20.2 17.5 40.7 68.7 47.3 57.9 38.8 46.3 58.9 1.9 35.3 24.6 54.5 3.8 53.0 68.3 125.5 67.2 7.4 77.0 57.9 18.0 37.1 79.8 90.1 0.0 63.6 1.5 109.7 5.9 125.5 15.1 58.5 6.5 4.1 46.2 2.7 1.2 76.2 26.0 7.4 63.7 58.4 1.3 29.5 2.2 0.6 6.1 6.7 7.5 69.8 109.9 0.8 5.4 30.1 8.4 2.5 16.0 9.4 13.1 139.9 1.0 60.3 73.8 71.5 78.2 5.3 0.8 68.1 77.3 5.4 104.2 8.0 6.6 10.5 11.9 1.5 6.8 81.8 51.9 46.5 1.9 4.1 67.1 88.4 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX4 VASA ENSG00000152670 "DEAD-box helicase 4" Q9NQI0 5 55738017-55817157 "Enzymes, Predicted intracellular proteins" "Differentiation, Meiosis, RNA-mediated gene silencing, Spermatogenesis" "Developmental protein, Helicase, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 102 "testis: 149.7" "Group enriched" "Detected in some" 4 "Early spermatids: 565.1;Late spermatids: 184.1;Spermatocytes: 320.9" "Cancer enriched" "Detected in single" 37 "testis cancer: 3.0" "Region enhanced" "Detected in single" "white matter: 1.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.8;PC-3: 1.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026170, HPA037763, HPA037764" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "CAB026170: , HPA037763: AB_2675652, HPA037764: AB_2675653" "unprognostic (1.49e-1)" "unprognostic (1.15e-2)" "unprognostic (1.54e-1)" "unprognostic (2.58e-1)" "unprognostic (3.80e-2)" "unprognostic (3.03e-1)" "unprognostic (5.35e-2)" "unprognostic (3.91e-1)" "unprognostic (3.77e-2)" "unprognostic (3.28e-1)" "unprognostic (5.73e-2)" "unprognostic (5.43e-7)" "unprognostic (4.84e-2)" "unprognostic (1.12e-1)" "unprognostic (5.60e-2)" "unprognostic (1.55e-1)" 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.7 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 149.7 0.3 0.3 0.0 0.0 0.5 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.2 0.1 0.3 0.1 0.2 0.0 0.3 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 565.1 0.0 0.0 0.4 0.0 0.0 3.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 12.2 0.0 0.0 184.1 5.6 0.5 0.0 1.0 0.0 0.0 0.0 1.5 8.7 0.1 0.0 3.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 320.9 83.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 DDX58 "DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455302-32526208 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 79.0;BJ hTERT+ SV40 Large T+ RasG12V: 76.0;GAMG: 22.8" "CAB012643, HPA047193, HPA073217" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB012643: , HPA047193: AB_2679978, HPA073217: " "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 6.3 4.9 3.5 7.5 2.9 1.3 6.0 3.0 4.3 7.1 3.1 6.3 2.9 5.6 4.7 6.4 4.4 6.0 4.1 2.7 3.6 5.5 6.3 7.1 7.4 5.2 3.7 4.6 5.7 2.5 5.2 5.7 4.0 4.2 5.3 2.3 10.0 3.5 4.8 7.8 7.1 5.7 6.5 9.2 4.8 2.8 3.6 15.6 4.3 1.7 5.2 5.1 5.3 2.9 4.3 2.4 2.5 2.2 7.5 6.4 2.7 2.1 14.6 79.0 76.0 2.4 1.4 0.4 2.7 2.7 22.8 2.8 2.3 1.3 11.4 7.4 0.9 1.1 2.4 3.5 5.0 1.4 4.5 4.9 1.3 6.9 1.3 4.2 14.3 1.5 1.8 1.0 6.6 0.6 3.8 12.4 1.8 0.6 2.0 2.4 3.1 0.0 11.6 0.6 2.0 0.3 1.7 1.7 12.6 1.7 3.5 0.9 13.4 1.5 0.9 1.7 1.1 0.0 0.3 0.9 2.6 3.3 2.1 0.0 0.1 0.3 0.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.2 0.2 1.3 0.4 0.2 0.0 0.2 0.0 3.5 2.9 3.0 4.3 2.7 3.6 5.2 3.7 4.0 6.5 3.6 2.9 41.7 22.4 8.8 20.5 13.9 4.2 5.1 7.2 13.6 4.1 5.8 5.1 5.1 5.7 6.7 1.8 2.1 5.6 13.9 13.8 0.0 19.5 2.7 12.9 8.7 23.6 3.0 5.7 10.4 12.2 7.6 13.9 21.9 20.3 5.1 16.8 9.3 6.7 5.6 6.7 13.2 4.6 4.1 7.3 4.6 0.4 6.5 11.6 0.0 39.4 12.3 6.4 21.6 31.2 17.5 16.2 7.7 6.0 9.1 4.9 16.9 7.2 7.3 2.5 6.6 16.8 13.1 0.5 2.3 10.9 5.4 2.5 17.8 10.4 2.6 5.3 DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 32.8" "Group enriched" "Detected in all" 4 "granulocytes: 32.8;monocytes: 13.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 44.0" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA043211: AB_10794390, HPA055501: AB_2682838" "unprognostic (8.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.20e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.13e-1)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.69e-1)" 6.9 2.8 2.9 15.8 3.1 51.1 5.8 2.4 4.4 6.6 3.5 9.1 8.7 6.7 2.1 3.2 5.4 9.2 3.5 2.4 5.0 2.2 8.2 10.1 9.6 9.6 3.9 5.3 3.1 3.0 0.4 20.7 5.5 3.8 9.0 6.3 9.0 3.2 1.0 3.0 11.0 7.4 9.3 12.8 13.5 2.2 7.8 15.5 3.5 3.6 7.3 5.9 0.7 5.7 12.3 7.1 2.7 1.1 6.9 19.9 13.3 12.0 25.3 44.0 30.4 0.1 28.0 0.2 0.6 12.2 23.9 4.7 1.2 7.3 12.8 7.0 1.0 27.0 8.1 0.7 8.4 11.1 6.5 5.6 2.1 15.9 1.4 9.2 31.5 6.0 0.5 0.3 28.6 0.3 10.0 7.0 0.6 1.1 5.9 5.4 6.1 0.0 4.2 7.1 0.5 3.6 21.4 2.6 12.2 0.5 1.9 15.3 34.1 2.4 15.6 5.6 4.2 11.2 1.9 0.1 7.8 32.2 3.4 2.4 5.9 5.4 3.7 9.1 5.1 1.2 3.7 3.8 3.6 2.0 2.9 3.3 32.8 2.7 13.1 0.0 5.5 2.5 2.9 3.1 2.4 4.4 2.4 5.0 9.6 3.9 5.5 9.3 7.8 5.7 29.0 9.6 6.7 11.4 14.7 1.0 2.6 3.9 3.4 1.7 11.2 3.3 8.3 2.8 5.1 3.7 22.9 6.1 16.0 24.0 0.0 7.6 15.7 8.5 15.6 18.9 0.0 5.9 1.5 10.1 39.4 13.0 44.4 7.1 8.8 20.3 6.1 6.6 26.1 0.0 5.5 14.1 10.2 23.8 6.0 4.4 3.4 46.2 0.0 33.7 35.6 2.9 24.7 28.6 2.4 26.4 31.5 4.1 6.0 2.1 13.2 3.7 11.5 19.4 6.6 7.1 5.7 0.7 1.4 4.3 2.4 7.1 24.1 12.2 4.5 2.0 DENND10 FAM45A ENSG00000119979 "DENN domain containing 10" Q8TCE6 10 119104086-119137984 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 36.5;Cytotrophoblasts: 53.8;Extravillous trophoblasts: 27.7;Hofbauer cells: 56.0;Syncytiotrophoblasts: 45.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041159 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Centrosome, Cytosol" "HPA041159: AB_10793871" "unprognostic (1.75e-2)" "unprognostic (1.05e-1)" "unprognostic (1.05e-1)" "unprognostic (2.73e-2)" "unprognostic (1.90e-1)" "unprognostic (3.12e-1)" "unprognostic (1.88e-2)" "unprognostic (2.13e-1)" "unprognostic (3.08e-1)" "unprognostic (3.05e-2)" "unprognostic (4.46e-2)" "unprognostic (2.64e-2)" "unprognostic (6.68e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-2)" "unprognostic (2.65e-1)" "unprognostic (3.20e-2)" 16.7 14.3 18.7 14.0 20.2 32.4 14.0 18.7 23.6 14.2 17.4 17.9 12.6 13.3 16.7 20.5 11.4 12.7 15.5 18.8 19.2 26.1 31.1 12.6 13.1 19.8 18.9 20.9 9.4 18.0 2.9 15.6 19.8 13.4 14.4 10.6 10.9 10.6 17.6 18.7 15.2 13.2 19.8 14.1 14.2 7.3 19.3 13.1 19.9 11.1 14.6 14.8 9.3 21.7 23.7 24.9 38.6 45.5 75.9 59.1 15.9 32.3 85.9 29.4 30.1 23.7 35.8 16.1 12.8 41.4 33.8 42.2 25.7 28.0 27.0 29.2 24.1 3.8 11.5 32.9 75.4 11.0 10.3 63.7 31.5 20.9 32.6 75.0 36.1 16.8 7.8 22.9 42.0 20.0 17.2 48.5 23.6 22.1 14.6 17.0 40.6 14.3 38.6 25.9 6.9 27.7 21.7 30.2 67.5 36.1 24.9 48.5 36.6 23.3 12.3 28.9 19.4 23.0 10.0 17.7 35.9 54.7 11.2 44.9 26.6 55.6 6.9 31.8 6.6 3.9 10.9 10.0 16.6 3.6 5.7 7.1 40.0 6.1 36.4 5.0 20.4 11.6 18.7 20.2 18.7 23.6 18.8 19.2 19.8 18.9 19.8 19.8 19.3 21.7 9.3 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.5 0.0 0.0 0.0 0.0 53.8 11.8 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 27.7 9.0 0.0 0.0 0.0 0.0 0.0 0.0 56.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 45.3 1.7 0.0 0.0 0.0 DENND6B "AFI1B, FAM116B, MGC33692" ENSG00000205593 "DENN domain containing 6B" Q8NEG7 22 50309030-50327012 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 42.1;Late spermatids: 58.7;monocytes: 39.4;Respiratory ciliated cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 6.9;RPMI-8226: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018934, HPA021653, HPA029570" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA018934: AB_1848365, HPA021653: AB_1848366, HPA029570: AB_10602131" "unprognostic (2.50e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.41e-4)" "prognostic favorable (5.93e-5)" "unprognostic (9.39e-2)" "unprognostic (3.17e-1)" "unprognostic (1.89e-3)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (4.50e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (8.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-2)" 2.4 3.8 10.6 2.3 10.8 1.0 3.4 8.0 14.4 6.2 8.6 3.9 1.1 5.2 2.5 2.5 13.4 3.2 1.7 10.3 9.5 7.6 1.7 4.7 2.9 9.4 9.1 4.0 5.4 2.7 13.6 1.0 9.5 5.5 0.9 4.2 3.6 3.6 0.7 2.6 3.9 1.7 6.9 4.5 3.3 6.7 9.6 0.8 6.7 0.6 1.7 2.6 3.5 7.7 0.5 1.8 3.9 4.3 1.0 3.7 0.0 0.8 1.9 0.5 0.3 0.1 2.8 6.9 1.7 1.9 0.2 3.4 0.1 0.1 0.2 1.7 1.0 1.2 3.5 0.2 0.9 0.2 3.0 3.1 4.2 0.1 0.6 3.8 0.8 0.1 1.5 1.2 0.9 3.0 0.0 0.6 0.3 2.0 0.2 1.0 0.0 10.0 4.9 1.6 1.7 3.1 2.1 2.7 0.3 0.2 4.3 1.0 0.9 0.7 0.6 0.6 0.1 1.0 0.2 1.0 1.7 0.8 0.8 0.2 0.8 0.0 0.1 1.0 0.2 0.2 0.1 0.2 0.5 0.2 0.1 0.2 0.1 0.3 1.3 0.4 0.1 0.3 10.6 10.8 8.0 14.4 10.3 9.5 9.4 9.1 9.5 6.9 9.6 7.7 4.5 3.2 4.1 16.3 14.9 1.1 3.6 6.1 5.7 6.2 5.4 5.8 1.3 11.5 8.3 5.5 22.9 0.3 9.5 3.9 3.9 6.5 24.7 42.1 4.6 5.7 10.2 4.4 20.3 1.8 0.6 4.2 9.2 5.7 5.7 2.8 4.2 1.0 13.7 1.7 13.7 3.3 4.1 24.2 7.8 58.7 2.5 20.0 5.4 2.8 39.4 5.6 5.2 9.0 2.5 2.6 2.1 2.6 33.2 2.4 14.0 17.8 65.5 17.5 0.0 2.5 3.0 24.7 22.2 1.6 0.6 1.0 8.4 3.1 3.6 2.3 DFFA "DFF-45, DFF1, DFF45, ICAD" ENSG00000160049 "DNA fragmentation factor subunit alpha" O00273 1 10456522-10472529 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002679, HPA018859, HPA019938, HPA025230" Supported Supported "Plasma membrane,Cytosol" NA NA 8700 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "CAB002679: , HPA018859: AB_1847622, HPA019938: AB_1847625, HPA025230: AB_1847623" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" "unprognostic (3.59e-2)" "unprognostic (1.57e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.55e-1)" "unprognostic (9.24e-3)" "unprognostic (3.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.21e-2)" "unprognostic (3.46e-2)" "unprognostic (3.89e-2)" "unprognostic (1.88e-1)" 13.3 12.6 15.0 12.0 18.0 6.5 12.6 19.7 16.5 11.1 14.2 11.3 12.1 11.7 9.8 16.7 13.0 10.8 12.1 14.9 17.2 16.8 13.2 11.3 12.4 17.4 18.7 15.3 11.4 18.0 9.2 20.1 17.5 11.8 12.2 12.2 10.9 12.3 12.3 10.9 11.1 16.1 16.1 10.7 12.1 9.8 18.3 13.3 12.3 13.9 16.2 14.4 10.1 18.3 37.8 36.8 31.0 35.4 25.7 24.3 15.1 52.5 33.6 53.4 39.6 88.4 48.4 79.9 33.1 44.5 29.7 30.3 60.5 62.2 53.7 31.9 41.8 39.9 37.6 35.8 41.8 49.3 25.4 30.5 30.6 84.4 67.4 29.1 41.3 39.3 72.6 17.6 38.4 48.0 48.8 22.2 27.2 28.3 42.4 41.3 37.1 40.1 48.5 28.6 36.5 35.6 48.9 42.1 58.0 26.6 27.0 17.0 43.4 24.9 34.0 46.4 35.0 21.6 32.5 114.3 26.5 45.7 38.5 1.8 11.2 8.6 15.2 9.1 11.7 16.6 10.3 13.5 10.6 15.8 10.7 13.0 1.4 17.5 12.3 12.4 16.2 10.5 15.0 18.0 19.7 16.5 14.9 17.2 17.4 18.7 17.5 16.1 18.3 18.3 26.9 44.8 34.3 3.3 23.5 34.4 39.0 43.8 30.1 21.1 20.5 25.0 23.7 32.9 36.6 18.4 108.4 91.1 22.8 12.6 37.2 46.5 32.0 22.4 31.6 34.0 34.2 15.6 6.5 39.1 64.9 25.1 20.9 23.8 24.7 35.6 31.4 31.0 41.8 20.2 8.3 17.3 28.5 22.9 13.8 73.2 30.1 17.0 10.6 3.7 37.4 23.3 28.8 5.0 6.9 49.1 10.6 32.4 19.3 48.1 25.0 57.8 26.0 34.0 19.7 29.9 26.9 35.7 28.4 32.0 40.6 66.4 18.5 43.9 27.9 38.9 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362234 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 223.0;Excitatory neurons: 111.0;Inhibitory neurons: 63.5;Oligodendrocyte precursor cells: 334.8" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 2.1;eosinophil: 1.2;intermediate monocyte: 1.2;myeloid DC: 1.5;neutrophil: 2.6;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "dendritic cells: 1.5;granulocytes: 2.6;monocytes: 2.1" "Cell line enhanced" "Detected in some" "HDLM-2: 23.9;HL-60: 7.7;U-266/84: 9.4;U-87 MG: 14.3;U-937: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 1.6 4.2 14.2 0.8 17.4 9.3 1.1 28.2 11.9 2.2 0.0 3.2 1.4 1.2 8.0 4.6 4.1 0.9 9.1 20.4 3.6 1.3 0.8 3.8 0.9 20.1 6.5 1.2 0.5 5.7 6.0 7.8 20.8 1.3 0.8 1.7 0.8 1.8 1.8 0.8 1.7 2.4 0.6 0.9 2.1 0.3 9.6 0.5 1.8 1.0 0.8 3.4 1.7 13.2 3.2 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.7 0.0 3.3 0.2 0.0 0.0 0.0 23.9 0.0 3.2 0.0 3.5 0.0 7.7 0.3 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.4 0.4 0.1 0.1 2.6 0.4 0.0 1.4 1.7 0.0 2.6 0.0 0.0 0.6 0.0 0.9 0.0 2.0 0.0 0.1 4.9 0.0 0.0 0.8 2.4 2.9 0.0 9.4 0.0 14.3 7.0 2.6 0.0 2.1 1.2 0.0 1.2 0.0 0.3 0.0 0.0 1.5 0.1 0.0 0.0 2.6 0.0 1.5 0.2 0.0 0.7 14.2 17.4 28.2 11.9 20.4 3.6 20.1 6.5 20.8 0.6 9.6 13.2 0.1 0.0 1.7 223.0 3.1 0.4 0.2 0.0 0.6 0.1 0.1 0.4 19.4 1.5 0.0 1.8 0.0 0.1 0.0 0.0 0.0 1.4 2.6 0.3 0.1 5.0 0.0 0.4 111.0 1.2 0.0 0.5 0.5 0.1 0.0 0.3 22.1 0.0 2.1 1.7 63.5 0.1 0.0 3.2 1.4 4.2 1.8 3.4 0.0 12.2 5.2 6.8 0.0 334.8 7.8 1.0 0.1 0.4 0.2 0.4 0.1 0.9 0.0 0.1 13.1 1.8 14.5 0.0 0.2 0.4 0.4 0.1 0.1 0.9 0.1 0.4 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 256.5;Early spermatids: 99.1;Rod photoreceptor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 57.3 19.6 12.3 18.9 11.8 12.4 22.7 32.5 14.0 14.6 14.6 37.3 19.1 13.5 38.5 26.3 12.9 15.9 19.8 12.8 13.3 25.5 22.0 13.9 17.6 15.5 16.9 11.4 18.5 39.8 20.9 12.6 18.8 14.1 38.8 37.8 43.3 14.0 13.5 21.2 18.2 18.4 9.0 14.1 23.3 12.3 14.1 14.1 19.1 11.8 20.8 18.1 14.4 12.2 34.2 24.8 20.6 23.8 36.1 28.2 28.4 54.9 33.4 44.0 41.6 37.4 34.6 38.4 33.3 57.2 30.0 24.1 25.4 42.8 42.9 22.7 13.9 38.0 66.9 30.8 39.3 41.4 51.5 40.3 27.6 59.1 32.2 29.4 51.2 26.7 27.3 41.0 39.7 19.4 23.1 20.2 26.3 53.1 36.2 25.3 33.4 31.2 25.4 28.8 24.4 19.4 36.4 38.0 26.6 26.8 29.8 20.9 63.0 30.1 26.3 60.4 32.0 48.1 72.4 39.5 43.0 54.0 26.8 9.4 16.1 9.6 13.8 23.6 9.8 13.2 9.0 9.1 13.6 10.2 7.4 10.9 13.0 10.1 23.1 11.5 8.3 10.5 12.3 11.8 32.5 14.0 12.8 13.3 15.5 16.9 18.8 9.0 14.1 12.2 9.4 9.6 7.8 7.8 13.5 4.6 9.6 12.0 10.8 29.6 9.6 7.4 15.5 15.7 13.8 14.7 256.5 18.3 13.7 76.3 11.7 19.3 99.1 11.6 12.9 11.1 20.9 5.7 26.9 14.5 23.4 11.1 33.6 20.0 19.0 14.4 10.0 13.2 24.5 15.2 28.5 46.3 14.2 11.5 7.1 23.4 10.5 10.5 10.6 10.3 34.4 16.3 14.4 9.0 11.4 17.6 40.3 7.5 18.7 10.6 24.7 29.3 11.5 106.1 0.0 8.4 14.5 13.2 13.5 12.4 5.1 25.4 10.3 15.8 26.0 12.2 DHRS7B "CGI-93, DKFZp566O084, MGC8916, SDR32C1" ENSG00000109016 "Dehydrogenase/reductase 7B" Q6IAN0 17 21123364-21193265 "Predicted intracellular proteins, Predicted membrane proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012132, HPA016873" Uncertain Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 21: OE19 - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cell Junctions, Cytosol" "HPA012132: AB_1847658, HPA016873: AB_1847657" "unprognostic (1.90e-1)" "unprognostic (3.16e-2)" "unprognostic (2.71e-1)" "prognostic favorable (1.98e-8)" "unprognostic (9.83e-2)" "unprognostic (1.18e-1)" "unprognostic (3.46e-1)" "unprognostic (1.45e-1)" "unprognostic (5.02e-3)" "unprognostic (2.76e-1)" "unprognostic (1.70e-1)" "unprognostic (2.81e-1)" "prognostic favorable (3.95e-5)" "unprognostic (1.20e-2)" "unprognostic (6.26e-2)" "unprognostic (9.20e-2)" "unprognostic (3.97e-1)" 19.0 18.8 18.5 8.1 18.6 2.9 19.2 19.6 28.3 17.8 19.9 15.1 15.6 11.4 25.7 12.8 15.9 11.9 22.2 18.6 19.2 22.8 20.2 13.4 7.7 19.3 19.2 8.4 20.2 32.9 7.9 13.2 19.4 15.1 15.8 10.8 18.3 10.2 30.8 18.7 14.5 9.6 19.3 9.2 18.1 24.0 18.3 6.8 16.6 19.5 9.0 12.4 11.1 20.7 17.2 19.9 7.1 15.6 18.5 12.7 12.4 16.0 8.9 11.4 20.7 25.2 17.6 7.2 23.8 13.7 9.0 23.7 10.6 26.2 16.1 13.8 33.9 9.9 13.8 21.8 10.2 5.5 7.0 10.0 17.0 14.6 22.1 5.6 11.3 12.5 6.0 8.6 13.5 35.2 6.0 21.6 9.9 55.4 8.5 10.0 18.8 12.7 39.1 20.5 3.9 8.3 19.8 17.4 17.9 56.8 11.7 11.2 5.6 9.4 6.4 28.7 18.3 4.7 7.9 13.6 14.9 20.3 14.4 19.2 34.3 29.3 6.7 33.9 6.0 7.6 6.5 4.6 21.6 5.9 7.0 6.1 25.0 8.4 40.8 9.4 10.9 14.4 18.5 18.6 19.6 28.3 18.6 19.2 19.3 19.2 19.4 19.3 18.3 20.7 31.1 16.0 18.1 29.4 11.9 16.3 26.7 59.0 11.4 21.3 19.8 17.4 14.1 25.8 38.5 29.5 31.3 52.9 11.3 25.9 17.6 47.2 69.5 38.1 13.6 23.7 7.2 21.9 32.9 39.0 31.8 18.9 14.3 22.2 8.8 13.8 27.5 20.5 29.4 18.5 37.3 28.5 48.8 17.9 15.5 24.4 22.4 14.3 19.6 14.0 20.8 27.6 22.6 36.7 36.2 30.0 24.8 35.0 10.5 29.0 44.4 25.2 50.7 40.1 6.6 15.1 18.2 71.5 22.3 10.7 18.6 51.6 11.2 27.3 22.2 25.1 DIAPH1 "DFNA1, hDIA1, LFHL1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 564.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" 27.9 20.3 21.0 42.1 22.5 90.2 24.2 18.3 20.9 24.4 40.0 31.0 40.6 18.5 44.3 58.0 25.2 30.0 34.9 21.5 25.7 38.1 91.7 51.3 67.0 18.8 19.9 12.9 37.3 44.6 24.5 25.1 20.1 14.7 31.1 28.4 36.1 19.3 172.0 47.3 36.5 18.7 18.0 36.3 45.1 19.9 27.4 68.5 33.1 55.7 66.4 47.1 30.4 18.6 147.8 92.6 53.2 68.4 40.4 54.5 71.3 59.5 62.2 67.7 70.2 318.1 131.6 156.5 88.1 85.5 103.0 157.9 116.9 191.5 84.8 88.9 66.6 282.6 121.4 103.6 37.7 198.9 564.7 34.4 102.1 94.5 95.5 30.5 87.0 234.8 101.2 106.9 67.7 141.5 217.2 256.8 51.6 75.2 61.6 240.1 87.1 87.6 129.8 158.5 69.4 37.3 146.2 184.6 59.5 47.5 77.5 92.1 52.8 93.9 49.9 52.1 119.9 54.2 94.4 111.7 50.2 153.7 57.8 23.6 12.8 29.8 32.6 14.0 21.2 9.3 20.3 25.3 12.6 9.1 14.8 23.9 13.7 13.7 15.1 10.0 18.7 15.4 21.0 22.5 18.3 20.9 21.5 25.7 18.8 19.9 20.1 18.0 27.4 18.6 33.9 48.1 46.8 11.8 40.0 52.6 60.8 22.4 21.6 17.3 35.1 23.1 18.6 22.8 48.0 44.1 54.2 20.9 96.9 60.5 5.9 62.7 27.9 42.3 18.9 39.0 5.4 52.6 44.1 98.0 31.9 25.9 76.0 83.0 46.9 14.5 16.8 91.6 17.1 6.7 33.6 23.1 12.2 38.4 60.6 9.0 11.8 78.5 19.6 24.4 54.6 12.1 115.4 25.6 9.1 122.9 35.7 10.9 54.1 77.3 35.2 13.9 30.4 69.0 13.1 15.4 26.4 18.3 26.1 38.7 59.7 52.1 92.8 18.3 30.1 91.2 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DIO2 "SelY, TXDI2" ENSG00000211448 "Iodothyronine deiodinase 2" Q92813 14 80197526-80387757 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Thyroid hormones biosynthesis" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 163.9;thyroid gland: 355.8" "Cell type enhanced" "Detected in many" "Breast glandular cells: 150.7;Endometrial stromal cells: 158.3;Extravillous trophoblasts: 523.3;Muller glia cells: 246.4" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 34.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 80.8;fHDF/TERT166: 41.8;HeLa: 95.4;HHSteC: 44.2;SiHa: 168.1;SK-BR-3: 35.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048002 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA048002: AB_2680230" "unprognostic (1.22e-1)" "unprognostic (1.69e-1)" "prognostic favorable (1.67e-4)" "prognostic favorable (4.62e-6)" "unprognostic (2.76e-1)" "unprognostic (1.22e-1)" "unprognostic (2.22e-1)" "unprognostic (2.17e-1)" "unprognostic (2.07e-1)" "unprognostic (8.78e-2)" "unprognostic (3.68e-2)" "unprognostic (2.48e-1)" "unprognostic (1.00e-3)" "unprognostic (5.08e-2)" "unprognostic (3.43e-1)" "unprognostic (8.40e-2)" "unprognostic (7.15e-2)" 1.5 3.0 18.0 0.6 15.3 0.1 15.3 15.0 24.6 163.9 5.9 1.3 1.3 40.2 0.5 58.9 0.7 5.1 11.9 17.1 13.0 5.0 0.1 1.6 0.8 13.6 19.2 0.2 1.8 6.6 31.6 14.5 17.4 9.0 1.7 7.4 33.3 30.4 6.5 7.1 1.5 4.5 5.5 0.6 5.3 4.7 13.3 1.2 355.8 70.7 33.1 6.0 25.0 16.6 0.2 9.5 0.0 0.0 0.5 1.4 0.3 80.8 16.6 6.2 0.9 0.0 0.3 0.2 0.2 41.8 0.3 1.7 2.9 0.0 6.1 0.0 0.2 0.0 95.4 0.0 44.2 0.0 0.2 5.1 0.0 1.2 0.0 3.9 1.4 0.0 0.0 0.8 0.5 1.9 0.1 0.1 1.7 0.0 0.5 0.8 3.9 0.1 0.0 0.8 0.0 0.2 168.1 35.3 0.3 7.1 0.1 0.0 0.8 0.3 7.0 17.4 20.1 2.8 0.0 0.0 7.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 15.3 15.0 24.6 17.1 13.0 13.6 19.2 17.4 5.5 13.3 16.6 0.1 0.0 0.5 52.9 0.3 2.9 0.1 0.0 2.2 3.3 150.7 34.4 1.9 0.0 0.0 0.0 0.0 4.8 0.5 0.2 0.0 0.0 29.5 14.2 158.3 2.3 0.0 0.0 1.0 0.0 523.3 24.6 0.0 15.6 0.0 0.1 0.7 0.2 9.2 1.7 1.0 0.5 0.0 1.3 5.7 12.5 3.4 1.3 5.4 4.7 0.0 246.4 0.0 8.5 1.4 1.0 0.0 4.1 0.3 0.3 0.0 0.0 0.0 7.8 0.0 69.1 6.5 9.7 0.7 8.9 3.0 28.2 1.7 0.9 0.1 0.1 DIRAS1 "Di-Ras1, GBTS1, RIG" ENSG00000176490 "DIRAS family GTPase 1" O95057 19 2714567-2721372 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.8;heart muscle: 105.0;tongue: 51.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Distal tubular cells: 31.3;Excitatory neurons: 20.4;Horizontal cells: 89.2;Inhibitory neurons: 25.9" "Cancer enhanced" "Detected in many" "glioma: 17.4;melanoma: 13.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 43.4;REH: 49.2;SH-SY5Y: 27.8;THP-1: 34.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050164 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" Nucleoplasm "HPA050164: " "unprognostic (7.43e-2)" "unprognostic (1.13e-1)" "unprognostic (2.33e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (4.19e-3)" "unprognostic (8.01e-3)" "unprognostic (2.68e-1)" "unprognostic (5.62e-2)" "unprognostic (3.60e-2)" "prognostic favorable (4.78e-4)" "unprognostic (3.00e-1)" "unprognostic (1.79e-3)" "unprognostic (5.47e-3)" "unprognostic (1.51e-1)" "unprognostic (1.03e-1)" "unprognostic (6.91e-4)" 1.8 2.5 10.5 1.2 20.7 0.7 1.9 16.1 84.8 7.0 0.0 1.4 1.2 12.7 2.5 5.4 6.6 0.7 105.0 19.8 16.9 4.8 0.1 0.6 0.6 17.1 17.4 2.7 6.7 17.0 22.4 0.3 14.5 3.3 1.1 11.5 6.7 1.8 2.7 1.9 2.2 7.4 0.0 4.2 3.5 6.0 45.2 0.1 0.5 51.8 0.7 4.0 2.4 34.8 0.1 2.2 7.0 24.1 0.9 3.1 0.1 8.2 2.8 0.4 0.1 1.4 0.4 0.0 1.0 21.9 12.2 0.1 10.1 0.0 0.0 0.0 15.6 0.5 0.8 0.9 1.0 0.0 43.4 1.4 5.1 0.1 0.1 4.6 0.0 0.2 15.0 7.2 2.8 3.6 0.2 0.4 15.2 0.0 3.3 49.2 0.0 11.7 0.0 0.0 3.1 27.8 0.3 1.1 15.6 1.2 1.1 34.2 0.0 5.3 6.6 0.2 2.6 16.4 12.4 8.9 11.8 0.5 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 20.7 16.1 84.8 19.8 16.9 17.1 17.4 14.5 0.0 45.2 34.8 0.0 0.0 0.0 1.6 6.9 1.1 0.8 0.2 2.2 7.9 2.6 2.8 18.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 31.3 1.4 0.4 0.1 2.2 0.3 0.0 1.3 20.4 2.0 0.5 0.9 0.0 0.3 0.0 2.3 0.0 0.0 5.7 89.2 25.9 0.0 0.0 0.0 3.6 1.1 1.2 0.5 3.6 4.7 0.1 4.6 0.0 2.0 3.4 1.5 0.0 0.0 0.6 0.9 0.0 0.1 0.0 6.1 0.0 0.7 2.1 0.7 0.4 0.3 0.4 0.3 0.1 0.0 0.0 0.2 DIS3L "DIS3L1, FLJ38088, KIAA1955, MGC4562" ENSG00000166938 "DIS3 like exosome 3'-5' exoribonuclease" Q8TF46 15 66293217-66333898 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041805 Approved Supported "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Centrosome "HPA041805: AB_10796783" "unprognostic (2.57e-1)" "unprognostic (5.37e-2)" "unprognostic (1.12e-1)" "unprognostic (3.99e-2)" "unprognostic (3.16e-1)" "unprognostic (1.40e-1)" "unprognostic (1.68e-1)" "unprognostic (2.94e-2)" "unprognostic (2.27e-2)" "unprognostic (1.28e-2)" "unprognostic (1.59e-3)" "unprognostic (1.86e-1)" "unprognostic (3.42e-3)" "unprognostic (2.66e-1)" "unprognostic (6.18e-2)" "unprognostic (9.58e-2)" "unprognostic (3.40e-1)" 11.0 11.8 7.9 6.2 9.8 7.6 9.3 8.9 8.6 10.3 7.7 11.1 5.1 11.1 9.5 7.5 9.6 5.5 12.7 8.0 9.1 8.3 11.0 5.9 7.6 8.7 9.4 11.1 12.8 15.8 10.0 5.4 9.6 8.7 6.0 11.4 8.9 9.0 23.2 7.4 7.7 8.8 8.8 8.7 9.0 9.8 8.9 7.8 11.0 28.3 7.2 9.6 8.1 12.2 14.0 32.6 10.6 14.1 12.2 16.4 12.4 9.5 11.1 14.3 13.2 17.6 10.1 51.6 10.3 13.4 14.9 23.3 25.7 9.2 9.2 12.0 24.1 26.7 25.1 20.1 9.5 27.7 10.1 6.9 9.7 4.5 14.8 9.7 13.1 17.7 18.6 12.6 14.4 12.3 13.8 17.3 15.4 12.7 20.0 18.3 42.1 30.0 5.7 18.9 17.1 15.7 22.3 7.6 11.4 10.0 10.6 21.8 14.4 18.7 16.8 7.4 18.7 10.1 36.9 24.0 6.4 35.9 7.8 8.5 5.1 4.3 7.6 6.1 10.2 6.5 7.7 10.0 8.5 7.8 8.8 7.3 0.6 11.7 13.2 6.7 8.0 6.7 7.9 9.8 8.9 8.6 8.0 9.1 8.7 9.4 9.6 8.8 8.9 12.2 7.1 6.4 16.2 22.5 14.6 4.2 5.5 4.0 17.1 15.6 9.4 7.6 30.3 15.7 7.1 3.7 4.2 17.0 9.6 5.0 5.9 6.5 7.1 8.3 14.6 10.2 3.0 24.2 11.4 3.5 4.5 12.4 10.7 7.3 16.5 25.1 7.1 19.2 9.6 10.1 17.2 10.6 8.2 12.3 7.8 9.9 19.9 10.1 1.8 13.1 14.4 17.7 12.3 22.6 23.1 3.3 5.1 20.3 18.4 4.8 5.4 9.8 8.1 23.2 19.7 9.5 10.1 28.5 17.2 12.1 5.4 3.7 16.0 16.5 14.0 3.8 DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 422.9;Oligodendrocytes: 1542.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016307, HPA069593" Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Plasma membrane" "CAB016307: AB_2092015, HPA069593: " "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.79e-2)" "unprognostic (4.56e-3)" "unprognostic (3.54e-2)" "unprognostic (8.56e-2)" "unprognostic (8.90e-3)" "unprognostic (2.97e-1)" "unprognostic (5.98e-2)" "unprognostic (2.33e-1)" "unprognostic (2.41e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-3)" "unprognostic (3.56e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (3.07e-1)" 20.7 14.5 26.4 14.7 57.0 16.2 18.4 33.2 36.4 23.8 15.4 24.2 24.0 19.7 11.6 37.6 16.1 17.1 19.4 25.4 29.3 27.6 25.9 18.0 14.7 36.9 43.3 23.3 17.2 31.7 14.4 21.3 34.8 15.9 26.3 38.8 20.2 18.6 25.2 18.8 25.4 21.2 19.9 13.0 22.9 15.5 50.3 27.1 43.3 28.2 20.6 20.3 20.5 73.5 128.0 20.0 40.3 75.7 34.2 36.2 40.7 52.2 46.2 49.2 59.0 60.4 59.8 41.5 127.1 47.7 95.7 86.4 39.3 76.4 97.7 10.9 22.5 35.2 31.1 40.5 35.2 35.0 33.3 27.8 43.3 49.1 101.3 163.1 64.8 32.2 26.7 51.4 125.6 41.5 51.3 12.9 35.3 71.1 35.4 26.7 51.6 26.8 51.9 55.3 19.7 32.3 72.9 49.5 49.4 46.7 108.8 26.0 62.5 127.5 33.5 36.1 79.9 76.0 50.6 50.6 50.3 51.8 40.0 2.5 0.7 1.2 0.8 0.7 1.3 1.6 1.3 0.9 0.8 1.2 1.3 1.3 2.4 1.1 0.4 1.1 1.0 0.8 26.4 57.0 33.2 36.4 25.4 29.3 36.9 43.3 34.8 19.9 50.3 73.5 24.0 25.6 25.7 113.3 28.5 53.3 52.3 45.5 40.5 42.0 29.6 23.0 25.6 35.8 44.6 49.7 95.9 48.9 25.2 72.4 5.9 22.8 12.9 51.8 37.4 28.1 28.9 17.5 422.9 20.2 19.5 27.7 51.5 68.5 12.0 29.9 27.8 54.6 14.9 37.0 117.8 34.4 28.5 26.4 26.0 19.2 28.6 19.2 37.4 165.8 18.3 71.9 43.3 257.3 1542.2 30.3 48.0 25.6 34.1 52.3 50.6 20.8 66.3 101.7 13.1 40.5 25.5 31.2 37.9 66.7 70.8 25.0 30.6 29.3 38.8 106.8 DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3292.3;Inhibitory neurons: 2602.7;Oligodendrocyte precursor cells: 2331.8;Oligodendrocytes: 4213.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.2;SH-SY5Y: 8.1;T-47d: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" 1.6 11.0 29.5 1.1 48.7 0.3 2.1 3.6 55.8 1.8 0.0 2.3 1.2 2.9 4.1 7.5 5.7 2.1 3.0 64.4 18.1 3.6 2.8 1.7 1.1 13.5 8.2 5.7 3.3 7.3 10.0 2.4 10.3 4.0 1.4 25.4 3.1 4.6 0.8 20.2 1.2 2.2 11.9 2.5 1.5 8.1 10.5 7.3 15.5 0.7 2.9 1.7 2.6 88.4 0.6 0.3 0.9 0.5 0.6 0.7 8.2 0.2 0.5 0.4 0.3 7.4 1.1 1.3 1.3 0.4 0.5 0.8 2.3 0.7 0.4 0.8 0.9 1.3 5.0 0.2 0.1 0.4 1.1 0.5 0.5 1.0 1.0 0.4 0.5 1.9 1.2 3.5 0.7 0.9 0.6 1.3 6.0 0.8 1.3 1.4 2.0 0.9 0.4 0.3 5.9 8.1 0.8 5.1 0.4 7.2 21.2 0.0 0.3 2.2 1.8 2.1 0.3 0.8 2.9 5.6 0.8 0.7 0.2 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.2 0.0 0.0 0.1 0.5 0.0 0.0 29.5 48.7 3.6 55.8 64.4 18.1 13.5 8.2 10.3 11.9 10.5 88.4 7.0 3.2 10.4 742.8 1.3 3.3 3.6 0.3 9.1 298.1 4.4 5.2 8.3 2.8 1.8 7.3 275.2 7.9 1.8 1.5 9.8 0.7 21.5 1.3 2.7 3.6 4.2 0.0 3292.3 0.4 0.5 7.4 1.1 2.4 0.0 1.6 2.2 4.6 4.0 23.5 2602.7 1.1 0.0 0.3 0.0 16.4 7.8 0.8 1.8 487.2 0.6 11.0 0.0 2331.8 4213.8 0.4 0.1 6.4 0.1 2.0 0.6 2.7 0.9 48.2 6.6 7.1 4.1 11.3 3.2 6.2 8.5 2.1 1.7 12.1 0.9 0.8 DLG5 "KIAA0583, P-dlg" ENSG00000151208 "Discs large MAGUK scaffold protein 5" Q8TDM6 10 77790791-77926755 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 112.5;Glandular and luminal cells: 139.6;Horizontal cells: 186.7;Syncytiotrophoblasts: 171.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "PC-3: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001746 Supported "Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA001746: AB_2666418" "unprognostic (1.36e-1)" "unprognostic (2.30e-1)" "unprognostic (1.07e-1)" "unprognostic (6.48e-2)" "unprognostic (1.13e-1)" "unprognostic (2.94e-2)" "prognostic unfavorable (5.38e-4)" "unprognostic (8.48e-2)" "unprognostic (6.41e-2)" "unprognostic (1.68e-2)" "unprognostic (2.02e-2)" "unprognostic (2.60e-1)" "unprognostic (8.00e-2)" "unprognostic (3.06e-1)" "unprognostic (5.13e-1)" "unprognostic (6.00e-2)" "unprognostic (2.74e-2)" 11.9 51.8 8.3 0.5 8.1 0.2 19.4 7.7 8.5 24.4 9.4 28.6 0.3 25.1 16.3 19.7 17.7 1.1 7.4 8.1 8.6 8.8 4.6 8.6 0.4 17.2 9.6 19.5 11.1 6.1 33.9 2.4 10.2 31.2 1.7 4.2 16.8 2.9 26.3 36.3 12.5 2.2 10.1 4.1 16.4 6.2 8.6 1.2 22.3 0.9 1.4 20.3 22.2 10.3 5.7 0.1 4.5 4.9 6.8 2.9 2.9 6.3 3.7 1.1 1.1 0.0 3.8 0.0 6.0 3.2 1.9 6.0 2.3 3.4 4.2 2.0 7.5 1.1 0.0 7.0 6.5 0.4 1.5 3.3 8.1 0.2 9.8 8.2 0.4 0.1 3.0 0.0 3.4 2.0 0.6 1.8 4.3 7.0 20.0 4.1 1.4 0.3 4.8 0.0 1.5 4.2 2.7 5.7 2.2 6.1 2.3 1.1 1.9 1.2 9.2 1.2 5.7 0.0 0.7 0.5 1.2 1.2 0.6 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 8.3 8.1 7.7 8.5 8.1 8.6 17.2 9.6 10.2 10.1 8.6 10.3 5.2 6.4 5.4 21.2 0.5 29.6 24.2 20.2 12.0 18.3 41.9 28.3 2.8 12.8 13.6 20.2 16.7 112.5 12.1 12.2 0.0 6.7 16.4 55.6 41.7 4.9 2.4 0.0 24.0 5.9 23.6 12.5 8.2 139.6 1.3 49.4 3.3 3.3 13.1 186.7 28.3 10.4 8.2 0.0 3.9 10.2 18.6 1.8 8.8 10.3 0.8 46.4 9.2 19.1 13.6 12.4 7.6 18.4 6.8 25.4 15.2 2.1 34.6 15.3 26.3 24.2 15.1 1.6 7.6 10.8 24.2 171.6 5.5 10.4 10.1 23.5 DLGAP3 "DAP3, SAPAP3" ENSG00000116544 "DLG associated protein 3" O95886 1 34865436-34929650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.6" "Cell type enhanced" "Detected in many" "Early spermatids: 18.9;Excitatory neurons: 39.1;Horizontal cells: 21.9;Inhibitory neurons: 27.9;Late spermatids: 19.3" "Cancer enhanced" "Detected in some" "testis cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 8.0;NTERA-2: 4.2;SCLC-21H: 12.5;SH-SY5Y: 2.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026445, HPA027304" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Endoplasmic reticulum" "Plasma membrane, Midbody" "HPA026445: AB_1847733, HPA027304: " "unprognostic (8.63e-2)" "unprognostic (8.58e-2)" "unprognostic (1.48e-1)" "unprognostic (5.77e-7)" "unprognostic (4.01e-2)" "unprognostic (5.51e-2)" "unprognostic (2.95e-2)" "unprognostic (8.78e-2)" "unprognostic (2.66e-1)" "unprognostic (1.69e-1)" "unprognostic (1.27e-4)" "unprognostic (2.13e-1)" "unprognostic (1.97e-2)" "unprognostic (6.12e-2)" "unprognostic (1.47e-1)" "unprognostic (2.26e-1)" "unprognostic (2.21e-1)" 0.3 0.4 46.9 0.5 41.2 1.1 0.2 0.0 48.2 0.2 0.0 0.3 0.2 0.3 0.0 0.1 0.3 0.1 0.1 36.0 19.1 1.3 0.1 0.2 0.3 0.0 17.8 0.1 1.1 0.2 4.8 0.0 0.0 0.2 0.0 1.8 0.2 0.2 0.1 0.2 0.5 0.0 0.0 1.9 0.3 7.5 51.6 0.3 0.4 0.0 0.1 0.2 0.2 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 8.0 0.1 0.0 1.0 0.0 1.3 0.0 0.0 0.1 0.1 0.6 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.2 0.0 1.3 0.0 0.0 4.2 0.0 0.0 0.4 0.0 0.1 0.0 0.4 12.5 2.4 0.1 0.1 0.0 0.2 0.3 0.0 0.1 0.0 1.3 0.0 0.0 0.1 0.2 1.6 0.1 0.1 0.1 0.1 0.6 0.0 0.0 0.3 0.2 0.0 0.1 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.2 0.2 46.9 41.2 0.0 48.2 36.0 19.1 0.0 17.8 0.0 0.0 51.6 0.0 0.2 0.0 0.0 1.0 1.8 0.3 0.9 0.8 1.8 4.1 0.7 0.8 1.0 0.0 0.1 1.8 4.2 0.1 0.9 0.8 3.9 0.4 18.9 0.2 0.1 0.4 1.2 0.0 39.1 0.6 0.2 0.4 0.0 0.1 0.0 0.3 0.4 0.1 10.1 21.9 27.9 0.4 0.0 7.1 0.6 19.3 0.9 4.1 0.0 1.9 0.7 1.5 1.0 8.0 0.7 0.2 0.0 0.0 0.8 0.2 1.3 0.8 0.0 2.2 0.0 0.7 0.4 3.4 4.9 1.1 0.3 0.0 1.3 0.1 0.9 0.6 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DLL3 SCDO1 ENSG00000090932 "Delta like canonical Notch ligand 3" Q9NYJ7 19 39498895-39508481 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 5.7;choroid plexus: 2.3;pituitary gland: 3.4;testis: 1.4" "Group enriched" "Detected in some" 4 "Oligodendrocyte precursor cells: 24.6;Spermatogonia: 39.5" "Group enriched" "Detected in many" 11 "glioma: 29.2;melanoma: 15.5;testis cancer: 8.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "memory B-cell: 2.6;naive CD8 T-cell: 1.4" "Group enriched" "Detected in many" 13 "B-cells: 2.6;T-cells: 1.4" "Cell line enriched" "Detected in some" 6 "SK-MEL-30: 83.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA024559, HPA056533" Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 65: Brain - Ion transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA024559: , HPA056533: " "unprognostic (2.52e-1)" "unprognostic (3.81e-1)" "unprognostic (3.13e-2)" "prognostic unfavorable (2.94e-4)" "unprognostic (9.85e-2)" "unprognostic (1.41e-2)" "unprognostic (1.65e-3)" "unprognostic (1.85e-1)" "unprognostic (4.82e-2)" "unprognostic (6.58e-2)" "unprognostic (1.06e-2)" "unprognostic (4.20e-2)" "unprognostic (3.82e-4)" "unprognostic (4.94e-2)" "unprognostic (5.13e-2)" "unprognostic (4.15e-2)" "unprognostic (2.97e-1)" 0.0 0.0 5.1 0.1 5.7 0.0 0.0 3.1 5.6 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 4.7 0.0 0.0 0.0 0.1 4.9 4.7 0.2 0.0 0.5 3.4 0.0 4.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 4.4 0.1 0.0 1.4 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.4 0.1 3.9 0.9 2.0 0.0 0.0 0.6 1.1 0.0 0.7 0.2 0.5 0.9 0.1 3.7 0.0 1.5 0.1 2.3 1.0 0.2 1.2 6.0 0.2 0.1 0.3 0.3 1.0 4.6 0.0 0.0 0.1 0.1 0.1 0.1 4.3 1.1 0.1 0.3 0.0 0.2 0.0 0.7 0.0 6.2 0.6 0.2 0.2 0.2 0.2 13.6 14.1 2.9 0.1 83.7 0.3 0.0 0.2 0.0 0.0 2.6 0.1 1.0 1.4 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.0 0.3 0.0 0.1 2.6 0.1 0.5 0.1 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 5.1 5.7 3.1 5.6 4.7 4.7 4.9 4.7 4.2 4.4 4.6 5.4 0.3 0.0 0.0 0.3 1.1 0.3 0.3 0.4 0.0 0.5 1.3 4.7 0.5 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.7 0.6 0.1 0.7 0.2 3.0 0.0 1.7 0.6 0.6 1.0 0.5 0.3 0.0 1.7 0.0 0.0 0.3 0.0 3.4 0.3 0.0 0.0 0.0 2.2 1.2 0.1 1.8 0.0 0.0 0.9 0.0 24.6 0.5 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.7 6.6 0.0 0.6 6.5 39.5 0.2 0.1 0.3 0.5 1.7 0.0 0.1 DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" 24.6 19.1 27.7 12.3 23.4 7.3 23.0 10.5 31.7 29.1 10.8 40.3 9.7 39.6 6.7 18.2 29.4 11.8 43.1 30.0 18.6 18.7 10.2 22.6 11.2 17.5 19.9 29.1 18.1 10.3 29.6 15.0 15.1 25.2 7.4 11.9 17.1 12.2 44.0 15.5 18.3 14.8 8.9 17.0 25.0 36.5 20.2 10.3 23.1 20.1 7.1 30.6 23.2 14.5 31.6 34.3 30.4 21.2 18.1 22.9 23.3 26.9 18.8 23.5 21.2 20.6 17.1 13.2 15.4 30.4 28.8 23.4 16.1 13.4 12.3 38.6 30.0 11.4 37.3 18.2 22.4 1.4 17.6 21.5 16.2 22.0 31.2 26.7 20.3 8.3 28.2 28.9 18.6 25.8 16.0 9.0 13.8 20.6 22.2 16.3 11.0 14.5 14.6 29.7 30.4 33.6 28.9 22.2 19.5 13.4 19.4 7.7 43.3 27.0 26.6 18.1 40.7 41.1 27.4 15.0 28.1 2.1 31.8 0.6 0.2 0.2 1.4 0.6 1.1 0.6 1.2 1.1 0.2 1.4 0.4 0.8 0.6 1.8 0.8 0.2 0.7 0.3 27.7 23.4 10.5 31.7 30.0 18.6 17.5 19.9 15.1 8.9 20.2 14.5 18.8 6.4 4.7 8.1 6.9 8.4 13.9 4.5 2.2 34.5 11.8 9.8 28.5 10.0 4.4 9.2 60.5 7.3 10.6 10.4 5.9 7.3 17.2 12.4 18.9 16.2 26.3 9.3 8.1 10.6 9.6 15.3 6.1 11.2 11.4 23.3 20.0 4.6 2.0 52.2 7.5 7.9 10.2 4.8 11.4 57.7 17.1 2.6 5.4 5.6 0.9 23.3 14.4 10.1 5.8 13.8 7.2 17.0 6.8 11.5 5.6 7.1 8.9 41.2 13.1 24.5 19.0 10.8 15.7 4.6 7.0 5.5 9.0 20.6 8.1 11.5 DNAAF1 "CILD13, DAU1, FLJ25330, LRRC50, ODA7, swt" ENSG00000154099 "Dynein axonemal assembly factor 1" Q8NEP3 16 84145287-84178767 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 22.7;testis: 45.3" "Cell type enhanced" "Detected in many" "Early spermatids: 116.2;Endometrial ciliated cells: 311.3;Plasma cells: 225.4;Respiratory ciliated cells: 494.5;Spermatocytes: 116.2" "Cancer enriched" "Detected in many" 5 "endometrial cancer: 3.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.3" "Group enriched" "Detected in many" 4 "granulocytes: 2.3;T-cells: 1.0" "Cell line enhanced" "Detected in some" "Hep G2: 1.7;Karpas-707: 4.9;PC-3: 1.4;SK-BR-3: 1.4;U-266/70: 4.0;U-266/84: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA041166, HPA074239" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "Nuclear speckles" "HPA041166: AB_10794190, HPA074239: AB_2732250" "unprognostic (5.25e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-2)" "prognostic favorable (2.14e-4)" "unprognostic (1.42e-1)" "unprognostic (9.99e-2)" "unprognostic (1.25e-1)" "unprognostic (4.48e-2)" "unprognostic (7.71e-2)" "unprognostic (1.58e-1)" "unprognostic (3.31e-5)" "unprognostic (2.70e-2)" "unprognostic (4.61e-3)" "unprognostic (1.77e-1)" "unprognostic (1.56e-1)" "unprognostic (1.27e-4)" "unprognostic (7.51e-4)" 0.3 0.7 1.4 0.1 1.2 1.2 0.3 1.1 1.9 2.2 9.7 0.3 0.0 0.5 1.4 0.4 22.7 0.0 0.4 1.6 1.5 1.0 0.8 3.5 0.0 4.1 7.3 0.4 0.3 0.3 2.4 0.2 4.3 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.0 3.0 0.7 0.2 45.3 1.6 0.0 1.6 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 4.0 2.8 0.4 0.1 0.0 0.0 1.3 0.2 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 2.3 0.3 0.1 0.4 1.0 0.3 1.4 1.2 1.1 1.9 1.6 1.5 4.1 7.3 4.3 3.0 1.6 1.3 1.1 0.0 12.4 1.6 5.7 0.6 1.5 9.6 0.0 1.4 4.5 1.5 0.7 1.5 67.2 3.7 54.2 0.2 0.5 0.1 0.0 1.3 116.2 311.3 4.4 1.9 0.0 0.0 9.6 0.4 0.4 2.4 0.5 14.6 3.8 2.6 2.2 0.6 1.9 0.0 5.2 0.0 18.3 7.0 1.5 26.7 1.2 21.6 87.2 0.0 0.8 2.4 1.0 0.5 0.6 0.9 0.0 0.4 225.4 1.4 0.0 1.7 494.5 51.0 0.0 1.6 7.3 116.2 17.0 0.2 0.3 0.4 4.5 1.2 0.3 0.9 DNAAF4 "CILD25, DYX1C1, EKN1, FLJ37882" ENSG00000256061 "Dynein axonemal assembly factor 4" Q8WXU2 15 55410525-55508234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 171.5;Proximal tubular cells: 34.4;Respiratory ciliated cells: 102.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051048 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA051048: AB_2681325" "unprognostic (5.97e-4)" "unprognostic (3.60e-2)" "unprognostic (1.69e-1)" "unprognostic (7.45e-4)" "unprognostic (1.74e-1)" "unprognostic (5.30e-3)" "unprognostic (4.05e-2)" "unprognostic (3.08e-2)" "unprognostic (8.24e-2)" "unprognostic (2.91e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (5.29e-2)" "unprognostic (3.85e-2)" "unprognostic (3.06e-2)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" 1.0 2.0 4.7 1.1 4.7 1.2 3.3 3.6 6.8 2.8 8.4 0.9 0.6 3.7 10.6 1.2 11.1 2.2 1.0 4.8 5.8 5.0 0.5 4.3 1.1 5.1 5.0 2.6 2.1 8.5 3.5 0.7 3.8 2.0 0.9 27.5 1.5 2.0 0.8 1.7 0.8 2.0 3.6 1.3 1.0 11.3 6.7 0.7 8.6 0.5 0.9 1.4 0.7 3.7 7.0 4.8 4.9 10.4 2.0 3.5 1.5 1.0 2.6 3.2 3.6 1.0 2.9 0.6 4.4 2.1 5.2 2.1 1.9 2.7 3.7 2.4 2.5 2.6 3.2 1.7 1.8 5.4 4.2 2.2 5.7 7.6 2.9 5.1 7.2 2.2 0.8 0.3 4.8 2.9 1.3 4.7 2.9 11.0 3.7 1.1 2.3 0.9 17.6 2.3 4.9 10.7 4.3 1.3 6.5 4.2 6.2 1.4 2.5 5.0 2.5 4.4 5.2 2.1 5.4 1.7 8.3 1.3 1.5 0.1 0.7 0.5 0.3 0.5 0.3 1.4 0.5 0.5 0.6 1.3 0.7 0.5 1.4 0.4 0.5 1.9 0.7 0.3 4.7 4.7 3.6 6.8 4.8 5.8 5.1 5.0 3.8 3.6 6.7 3.7 4.1 12.8 15.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 7.9 9.8 0.0 0.0 15.5 12.9 0.0 2.0 0.4 0.0 5.9 13.6 0.0 171.5 9.0 2.8 0.0 0.0 0.0 5.1 1.5 3.4 0.0 13.3 2.5 9.7 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.4 0.0 0.0 34.4 102.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.5 0.7 7.2 0.0 0.0 DNAH17 "DNAHL1, DNEL2, FLJ40457" ENSG00000187775 "Dynein axonemal heavy chain 17" Q9UFH2 17 78423697-78577396 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 2.1;retina: 2.5;testis: 5.5" "Cell type enhanced" "Detected in some" "Bipolar cells: 56.4;Cone photoreceptor cells: 87.6;Early spermatids: 43.7;Late spermatids: 36.6;Oligodendrocytes: 52.5" "Group enriched" "Detected in some" 4 "head and neck cancer: 2.9;lung cancer: 1.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HeLa: 5.7;MOLT-4: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA024354, HPA076261" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 20: HeLa - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" "Nucleoplasm, Plasma membrane" Cytosol "HPA024354: AB_1847911, HPA076261: AB_2732305" "unprognostic (4.98e-4)" "unprognostic (2.26e-1)" "unprognostic (2.30e-3)" "unprognostic (8.70e-3)" "unprognostic (6.66e-2)" "unprognostic (9.23e-2)" "unprognostic (3.72e-3)" "unprognostic (8.41e-2)" "unprognostic (2.66e-1)" "unprognostic (1.11e-1)" "unprognostic (1.20e-3)" "unprognostic (8.35e-3)" "unprognostic (1.58e-10)" "unprognostic (5.25e-2)" "unprognostic (1.54e-1)" "unprognostic (5.12e-1)" "unprognostic (6.04e-3)" 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.5 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 5.5 0.6 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 5.7 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.2 0.0 0.2 1.6 0.8 1.3 0.9 0.6 2.1 0.4 6.4 0.5 0.7 0.6 0.6 0.3 0.1 0.0 56.4 0.1 0.0 2.5 0.0 0.0 0.0 87.6 0.0 0.1 0.0 0.0 0.0 43.7 1.4 0.5 1.0 0.0 0.0 2.2 0.0 0.0 0.3 0.0 1.7 0.0 0.1 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.8 1.7 36.6 0.6 2.9 0.0 1.0 0.1 1.5 0.0 1.0 52.5 0.1 0.0 0.4 0.4 0.3 0.0 0.1 0.0 7.8 0.0 0.6 0.5 17.4 0.6 0.0 0.1 0.0 0.3 0.4 0.0 0.1 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DNAJB13 "RSPH16A, TSARG6" ENSG00000187726 "DnaJ heat shock protein family (Hsp40) member B13" P59910 11 73951026-73970366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 53.2;testis: 18.9" "Group enriched" "Detected in some" 4 "Early spermatids: 90.6;Endometrial ciliated cells: 114.8;Late spermatids: 62.9;Respiratory ciliated cells: 104.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;Karpas-707: 2.6;RPTEC TERT1: 4.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052465, HPA061330" Enhanced Approved "Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA052465: AB_2681842, HPA061330: AB_2732659" "unprognostic (1.07e-1)" "unprognostic (3.23e-2)" "unprognostic (3.27e-3)" "unprognostic (1.56e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-4)" "unprognostic (1.30e-2)" "unprognostic (1.72e-4)" "unprognostic (5.00e-2)" "unprognostic (4.73e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (3.32e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-2)" "unprognostic (2.40e-2)" 0.1 0.1 1.5 1.2 1.5 4.4 0.2 1.0 1.4 5.5 12.2 0.1 0.6 2.0 5.2 0.1 53.2 2.2 0.1 2.0 1.9 1.0 0.1 3.1 2.1 4.8 5.7 0.3 0.8 0.1 1.1 0.5 3.6 0.9 0.0 0.4 0.6 2.9 0.3 0.1 2.9 0.1 4.0 1.3 0.2 18.9 2.4 0.0 0.2 0.0 0.0 0.2 0.1 1.8 0.0 0.4 0.3 0.7 0.0 0.1 0.2 0.1 0.0 0.2 0.0 0.7 0.2 0.9 2.1 0.2 0.3 0.5 0.1 0.0 0.0 2.7 0.3 1.0 0.9 0.3 0.0 0.2 0.6 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.2 2.6 0.4 0.3 0.6 0.9 0.2 0.2 1.5 0.4 1.2 1.1 4.5 0.5 0.3 1.0 0.5 2.2 0.2 0.4 0.3 0.7 0.0 0.0 0.6 0.6 0.0 2.2 2.0 1.9 0.0 0.3 0.1 0.7 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.1 1.5 1.5 1.0 1.4 2.0 1.9 4.8 5.7 3.6 4.0 2.4 1.8 0.2 3.2 0.0 2.0 0.0 0.0 1.9 11.1 0.0 0.2 0.1 0.3 0.2 0.0 7.6 1.8 0.0 0.1 0.0 0.1 0.0 1.7 90.6 114.8 2.4 0.2 0.0 0.0 0.4 0.0 0.1 0.5 0.0 13.4 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.3 10.2 0.0 0.0 62.9 1.2 0.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.2 0.0 1.3 1.4 1.0 104.2 0.9 0.0 1.1 3.3 19.5 1.5 0.0 0.0 0.0 0.3 0.0 0.0 1.2 DNAJB4 HLJ1 ENSG00000162616 "DnaJ heat shock protein family (Hsp40) member B4" Q9UDY4 1 77979175-78017964 "Plasma proteins, Predicted intracellular proteins" "Stress response" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 181.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 119.0;HUVEC TERT2: 182.3;LHCN-M2: 312.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004995, HPA028383, HPA028385" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 9500 "Cluster 44: Non-specific - Transcription" "Cluster 38: Heart - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Nucleoplasm "Plasma membrane, Cytosol" "CAB004995: AB_425882, HPA028383: AB_10599601, HPA028385: AB_10599944" "unprognostic (1.21e-1)" "unprognostic (4.36e-2)" "unprognostic (2.19e-1)" "unprognostic (5.50e-3)" "unprognostic (3.40e-2)" "unprognostic (4.76e-3)" "unprognostic (4.32e-3)" "unprognostic (3.93e-3)" "unprognostic (1.53e-1)" "unprognostic (2.16e-1)" "unprognostic (2.00e-1)" "unprognostic (3.22e-1)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.60e-2)" "unprognostic (1.51e-1)" "unprognostic (7.12e-3)" "unprognostic (1.01e-2)" 31.6 49.7 21.9 11.1 24.2 6.7 15.4 24.4 74.6 24.0 19.9 14.3 6.4 21.3 10.8 26.4 13.9 32.3 50.4 23.1 27.1 20.6 20.0 17.0 9.7 23.0 24.8 16.0 22.8 14.1 11.6 26.0 23.0 23.3 11.2 15.0 7.6 14.1 44.1 9.6 9.6 29.9 23.3 42.2 12.3 7.9 25.9 10.5 44.5 71.4 6.2 23.6 12.8 35.3 6.2 11.8 14.5 8.6 61.8 115.0 6.7 119.0 28.8 50.8 56.8 3.9 8.0 8.9 19.4 55.5 20.7 9.2 18.7 10.1 86.1 10.1 5.3 4.5 32.9 28.7 84.1 2.5 2.4 47.9 27.9 66.5 18.9 28.4 182.3 2.9 19.6 6.1 312.1 0.7 3.0 6.6 9.4 1.8 5.6 5.0 25.2 5.9 12.0 3.1 10.8 3.4 13.3 10.0 11.7 15.0 3.9 3.7 88.7 72.5 17.8 51.2 15.9 5.5 1.8 7.9 9.9 5.3 12.9 3.3 0.7 1.2 1.1 0.8 1.8 1.6 1.3 1.3 0.7 1.3 3.0 2.1 0.2 1.6 0.9 2.3 1.9 0.9 21.9 24.2 24.4 74.6 23.1 27.1 23.0 24.8 23.0 23.3 25.9 35.3 81.5 60.9 6.3 35.9 23.9 41.7 112.5 16.3 48.3 29.3 90.9 57.1 98.7 18.6 20.0 18.4 68.8 51.2 15.3 40.9 37.2 11.2 144.7 55.1 37.3 84.4 21.4 42.1 41.6 14.7 23.2 87.3 45.9 51.9 56.6 16.7 42.8 22.3 19.4 30.3 39.0 37.9 12.2 18.3 70.1 62.6 24.5 33.7 65.8 21.5 5.1 40.5 8.2 28.6 53.8 11.4 27.3 35.0 70.6 33.9 16.8 31.0 34.7 56.5 26.3 82.8 120.3 23.1 12.0 55.5 39.2 181.0 52.7 32.1 30.9 43.2 DNAJC18 MGC29463 ENSG00000170464 "DnaJ heat shock protein family (Hsp40) member C18" Q9H819 5 139408588-139444491 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "testis: 77.9" "Group enriched" "Detected in many" 21 "Early spermatids: 529.9;Late spermatids: 1332.4" "Cancer enhanced" "Detected in many" "glioma: 8.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036538, HPA060154" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions" Cytosol "HPA036538: AB_10670802, HPA060154: AB_2684212" "unprognostic (2.03e-1)" "unprognostic (1.16e-1)" "unprognostic (1.13e-1)" "unprognostic (1.19e-3)" "unprognostic (1.15e-1)" "unprognostic (1.24e-1)" "unprognostic (2.73e-3)" "unprognostic (8.76e-2)" "unprognostic (1.03e-1)" "unprognostic (1.90e-1)" "prognostic favorable (5.89e-4)" "unprognostic (8.09e-2)" "unprognostic (1.69e-2)" "unprognostic (3.55e-2)" "unprognostic (1.81e-1)" "unprognostic (6.96e-2)" "unprognostic (1.97e-2)" 6.1 3.1 7.7 1.5 7.4 0.9 5.2 7.9 9.5 6.9 4.5 5.8 0.7 6.5 2.3 2.4 6.6 2.1 6.6 7.2 8.3 5.1 1.0 6.8 1.7 8.3 7.2 7.5 1.9 3.6 8.0 2.1 8.6 4.5 1.3 7.6 3.0 2.9 7.5 2.4 3.4 3.5 6.6 2.8 3.5 77.9 7.6 1.6 4.3 4.3 1.2 5.4 4.7 8.1 1.2 1.2 7.9 7.4 4.3 4.5 0.9 2.4 5.3 4.2 7.6 2.9 0.9 5.4 6.4 3.8 9.2 2.1 4.5 7.3 4.4 12.5 5.9 3.7 2.6 1.3 3.4 0.4 1.7 6.1 0.9 7.0 4.3 7.1 5.8 2.0 1.7 5.1 6.3 0.6 1.6 1.7 5.4 0.4 1.8 4.5 8.5 0.9 2.5 1.3 7.3 7.6 2.5 0.9 5.8 10.1 1.1 2.7 7.5 5.5 0.0 1.7 5.2 6.0 8.6 2.8 2.9 2.7 2.4 0.5 0.4 0.5 0.5 0.3 0.7 0.8 0.7 0.9 0.3 0.9 0.7 0.4 0.1 1.4 0.2 0.5 1.7 0.3 7.7 7.4 7.9 9.5 7.2 8.3 8.3 7.2 8.6 6.6 7.6 8.1 14.9 3.2 3.9 12.7 5.0 1.5 8.3 9.4 7.4 29.4 2.2 5.5 11.0 2.8 5.8 1.8 10.4 4.7 7.0 0.7 1.9 4.9 529.9 2.1 11.0 15.2 12.6 1.7 33.1 1.1 3.4 11.3 2.0 2.3 9.5 14.4 13.6 0.2 2.9 16.8 39.0 2.1 0.0 3.5 2.4 1332.4 14.0 3.4 5.4 8.4 3.7 13.7 3.1 17.6 22.1 2.0 1.7 18.8 7.6 3.9 0.8 3.6 3.3 20.1 19.7 21.1 14.2 43.8 12.9 2.6 1.1 4.7 4.2 9.8 1.3 3.4 DNAJC5 "CLN4, DNAJC5A, FLJ00118, FLJ13070" ENSG00000101152 "DnaJ heat shock protein family (Hsp40) member C5" Q9H3Z4 20 63895126-63936031 "Disease related genes, Human disease related genes, Predicted membrane proteins" Chaperone "Disease variant, Neurodegeneration, Neuronal ceroid lipofuscinosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012139, HPA012737, HPA013154" Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane" Vesicles "HPA012139: , HPA012737: AB_1847293, HPA013154: AB_1847292" "unprognostic (9.96e-3)" "unprognostic (2.75e-1)" "unprognostic (3.91e-1)" "unprognostic (3.61e-2)" "unprognostic (1.65e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (8.82e-6)" "unprognostic (3.04e-2)" "unprognostic (2.73e-1)" "unprognostic (2.65e-2)" "unprognostic (1.78e-3)" "unprognostic (1.51e-1)" "prognostic favorable (7.70e-6)" "unprognostic (2.24e-2)" "unprognostic (3.54e-2)" "unprognostic (4.28e-3)" "unprognostic (1.08e-2)" 12.6 22.1 30.8 10.7 33.0 16.9 11.1 10.2 39.1 11.4 2.1 17.6 11.5 12.1 5.7 42.0 11.6 7.4 25.8 36.2 31.0 17.7 12.8 18.0 9.9 27.9 23.9 8.8 22.7 21.2 28.5 8.4 30.4 16.7 6.9 28.1 16.2 11.5 14.5 19.2 17.5 8.6 13.8 22.2 20.8 10.7 26.8 8.4 16.8 9.5 8.5 13.4 16.9 25.7 25.2 23.7 19.8 18.8 19.4 15.9 14.6 28.6 27.4 49.4 23.8 52.7 30.2 9.8 31.6 28.2 22.7 36.4 15.9 53.6 16.0 8.2 11.3 19.3 17.4 25.8 18.1 19.2 43.5 18.0 39.9 22.9 11.7 19.1 24.2 16.5 19.2 8.9 22.6 17.3 21.1 30.9 7.1 21.0 26.5 21.0 10.9 10.7 16.4 22.6 21.4 13.9 30.8 48.7 17.8 11.6 23.5 75.9 43.7 42.6 14.4 20.4 21.5 11.1 5.6 13.6 42.9 25.3 25.4 0.7 3.2 2.6 3.2 3.7 1.8 1.6 1.8 2.7 2.5 1.4 2.5 2.5 3.1 1.5 3.1 3.9 3.1 2.6 30.8 33.0 10.2 39.1 36.2 31.0 27.9 23.9 30.4 13.8 26.8 25.7 12.8 6.4 17.8 19.2 10.4 20.8 18.5 25.5 20.5 60.7 17.4 14.1 31.7 14.3 23.2 23.9 62.6 18.5 19.1 71.7 13.7 20.5 48.9 23.9 8.5 18.7 32.4 10.3 37.1 37.6 18.4 12.4 27.0 23.5 1.3 12.1 23.9 27.8 43.5 79.1 38.8 33.3 14.2 51.0 24.8 123.5 7.2 31.4 14.2 25.3 36.9 27.9 22.6 19.1 26.2 59.0 41.1 12.4 17.3 39.5 62.0 22.9 29.4 47.0 13.1 9.0 13.1 13.5 13.2 28.0 22.9 30.2 15.0 13.3 28.4 64.5 DNAJC6 "KIAA0473, PARK19" ENSG00000116675 "DnaJ heat shock protein family (Hsp40) member C6" O75061 1 65248219-65415871 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Chaperone, Hydrolase, Protein phosphatase" "Disease variant, Neurodegeneration, Parkinson disease, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 81.5;retina: 52.8" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 1038.1" "Cancer enriched" "Detected in many" 4 "glioma: 5.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 62.1;HEL: 165.8;K-562: 65.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031182, HPA054917" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoplasm, Plasma membrane" "HPA031182: AB_10611957, HPA054917: AB_2682641" "unprognostic (6.99e-2)" "unprognostic (2.00e-3)" "unprognostic (3.19e-1)" "unprognostic (7.94e-7)" "unprognostic (1.59e-1)" "unprognostic (7.61e-3)" "unprognostic (1.87e-4)" "unprognostic (2.98e-1)" "unprognostic (1.89e-1)" "unprognostic (4.14e-1)" "unprognostic (4.22e-3)" "unprognostic (1.53e-1)" "prognostic favorable (2.81e-4)" "unprognostic (1.43e-2)" "unprognostic (1.12e-1)" "unprognostic (1.36e-1)" "unprognostic (8.67e-3)" 1.5 11.1 34.7 0.9 43.3 4.7 1.1 33.7 46.9 0.8 0.0 2.1 1.0 0.6 0.4 0.3 1.1 1.0 8.9 42.1 48.0 7.7 0.4 1.5 0.2 60.2 51.3 0.5 2.1 1.0 12.6 7.4 67.6 1.1 1.7 52.8 0.7 0.7 0.4 1.1 1.0 0.9 27.2 2.1 1.7 2.2 42.0 0.8 1.7 0.8 0.3 1.1 0.9 81.5 10.4 2.8 0.1 4.4 2.1 0.5 23.4 20.1 33.1 32.6 31.7 2.7 0.5 9.9 1.7 8.3 8.0 2.5 14.6 3.3 25.8 62.1 6.9 165.8 5.1 0.6 0.2 5.6 3.9 2.7 2.2 3.3 13.8 6.0 0.7 8.0 65.5 1.2 6.6 1.9 2.1 0.0 6.5 0.0 2.2 0.0 4.9 0.4 23.7 0.0 39.4 27.0 11.9 15.5 5.4 37.4 7.5 0.3 6.5 4.8 3.3 0.6 5.9 6.0 4.1 3.0 13.4 4.1 8.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.7 43.3 33.7 46.9 42.1 48.0 60.2 51.3 67.6 27.2 42.0 81.5 0.8 0.0 0.5 49.3 0.5 1.3 0.4 0.5 0.0 30.4 0.6 0.3 28.0 2.8 0.2 0.0 14.6 8.9 1.5 0.4 1.9 0.8 2.0 1.8 0.5 3.7 7.2 19.4 237.4 0.7 2.1 5.8 1.5 3.0 0.0 0.6 0.4 0.1 1.2 52.2 237.6 1.9 2.0 0.0 0.8 1.9 0.0 0.7 7.2 18.7 1.1 4.1 0.0 136.7 1038.1 0.4 0.2 0.0 0.9 1.7 0.0 7.2 1.2 21.6 0.0 0.2 8.5 1.7 2.5 0.0 0.3 7.4 0.6 6.9 0.6 0.2 DNAJC9 "JDD1, SB73" ENSG00000213551 "DnaJ heat shock protein family (Hsp40) member C9" Q8WXX5 10 73183362-73247255 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 173.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035215, HPA035216" Supported Supported "Nucleoplasm,Plasma membrane" NA NA 39000 "Cluster 44: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA035215: AB_10603663, HPA035216: AB_2674522" "unprognostic (4.18e-2)" "unprognostic (1.61e-2)" "unprognostic (7.63e-2)" "unprognostic (2.67e-3)" "unprognostic (3.45e-1)" "unprognostic (6.83e-3)" "unprognostic (2.43e-3)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.20e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (7.07e-5)" "unprognostic (5.61e-2)" "unprognostic (3.08e-3)" "unprognostic (6.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" 9.2 10.6 17.1 17.6 17.5 91.9 15.4 19.2 21.5 11.2 15.4 16.0 14.6 12.8 12.4 16.9 9.7 6.9 8.6 16.9 17.0 10.0 13.4 9.6 28.2 16.4 16.5 15.3 8.7 10.2 10.6 17.6 16.9 11.4 18.0 25.1 11.3 11.2 11.5 17.7 13.9 11.8 15.7 14.8 12.2 12.4 17.0 35.8 8.4 13.1 32.3 11.5 11.9 17.6 135.0 77.3 93.8 68.4 16.1 19.3 45.7 101.5 59.4 101.1 106.1 130.8 89.4 86.9 33.5 43.6 43.7 83.1 92.9 67.5 118.1 98.5 63.8 188.3 79.4 93.4 14.8 173.1 71.0 14.8 33.2 107.1 93.4 36.4 66.2 112.1 168.3 103.0 81.4 118.4 155.0 124.7 36.3 64.4 215.1 114.2 85.1 47.6 52.9 61.5 44.3 73.4 73.5 114.5 52.9 43.7 62.1 76.8 48.0 65.2 118.3 71.3 168.0 45.0 70.6 141.8 64.8 162.9 45.9 23.9 3.7 29.1 25.5 10.7 29.2 32.8 31.3 28.2 6.5 28.3 30.3 26.9 4.5 24.8 10.9 20.3 36.8 18.0 17.1 17.5 19.2 21.5 16.9 17.0 16.4 16.5 16.9 15.7 17.0 17.6 17.3 9.6 12.3 11.1 39.5 47.7 34.1 31.9 33.0 26.1 21.5 24.8 2.7 17.2 24.8 9.2 8.4 107.8 44.6 18.3 21.5 31.5 80.4 15.9 14.0 20.6 12.0 173.8 11.8 31.4 111.4 17.6 12.2 19.0 42.3 26.0 13.9 9.8 61.9 15.2 12.8 25.6 54.9 10.9 19.6 43.3 14.0 17.4 32.0 6.5 23.0 29.5 32.0 7.5 6.5 44.1 16.7 20.3 49.7 27.6 18.2 16.3 21.9 43.2 26.3 17.7 28.3 28.7 65.4 38.2 43.5 58.0 45.2 19.7 38.0 37.5 DOC2A ENSG00000149927 "Double C2 domain alpha" Q14183 16 30005514-30023270 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 72.2;choroid plexus: 26.5;testis: 37.8" "Group enriched" "Detected in many" 4 "Early spermatids: 284.7;Late spermatids: 200.4" "Cancer enhanced" "Detected in many" "renal cancer: 5.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 13.1;MCF7: 10.8;REH: 11.0;SCLC-21H: 35.9;U-937: 17.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA065676 Uncertain "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 65: Brain - Ion transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Cell Junctions" "Nucleoplasm, Nucleoli" "HPA065676: AB_2685528" "unprognostic (1.46e-3)" "unprognostic (3.39e-1)" "unprognostic (2.30e-2)" "unprognostic (1.31e-1)" "unprognostic (4.26e-2)" "unprognostic (1.40e-1)" "unprognostic (3.66e-2)" "unprognostic (9.14e-2)" "unprognostic (3.90e-2)" "unprognostic (2.89e-2)" "unprognostic (1.28e-3)" "unprognostic (5.13e-2)" "unprognostic (8.29e-3)" "unprognostic (1.71e-1)" "unprognostic (2.74e-1)" "unprognostic (2.68e-1)" "unprognostic (2.61e-1)" 2.7 4.5 47.5 0.2 57.6 1.0 1.9 34.7 72.2 2.8 26.5 6.8 0.7 1.4 0.3 1.8 8.7 0.7 1.4 60.3 28.3 5.3 0.9 5.6 0.3 34.0 38.5 15.4 1.6 0.8 9.4 0.1 35.4 8.2 1.3 1.1 1.4 0.5 0.2 0.6 2.6 0.7 27.5 6.0 0.8 37.8 38.2 0.1 1.0 0.0 0.1 1.1 2.2 42.5 0.9 1.8 1.2 0.7 0.4 0.0 13.1 0.4 0.9 0.5 0.4 5.6 3.3 0.0 1.1 0.1 1.6 0.3 7.1 2.7 0.3 0.0 0.7 1.1 0.3 0.2 0.5 1.0 3.5 1.6 0.8 0.2 0.8 6.5 0.0 3.9 0.3 0.0 0.0 10.8 2.2 4.0 1.7 4.0 5.1 11.0 0.0 0.5 0.4 0.8 35.9 2.3 0.3 3.0 0.3 2.6 3.4 2.0 0.0 0.0 1.5 0.1 0.2 0.2 0.0 0.0 0.2 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.5 57.6 34.7 72.2 60.3 28.3 34.0 38.5 35.4 27.5 38.2 42.5 1.5 0.0 4.6 8.8 0.4 0.6 3.5 2.5 6.8 3.7 4.0 3.4 0.7 1.5 7.8 1.8 22.9 0.3 0.2 3.0 1.9 0.1 284.7 12.2 0.2 1.7 1.2 0.0 28.2 0.0 1.0 2.1 1.5 0.3 0.0 3.5 2.5 0.0 0.5 0.0 10.7 3.6 10.2 1.9 1.0 200.4 0.6 2.2 1.8 4.7 0.1 2.3 0.0 3.5 2.6 0.0 1.0 1.9 0.1 2.3 0.3 0.3 57.5 2.0 0.0 0.5 0.9 3.2 6.1 0.6 0.9 0.1 0.3 2.5 4.3 1.1 DOCK4 "FLJ34238, KIAA0716" ENSG00000128512 "Dedicator of cytokinesis 4" Q8N1I0 7 111726110-112206407 "Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" Proto-oncogene "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 41.6" "Group enriched" "Detected in many" 4 "Astrocytes: 791.0;Excitatory neurons: 422.8;Microglial cells: 1568.3;Oligodendrocyte precursor cells: 434.3;Oligodendrocytes: 815.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "neutrophil: 2.7" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 43.3;HUVEC TERT2: 75.5;TIME: 69.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071516 Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 65: Brain - Ion transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli, Plasma membrane" "Golgi apparatus, Cytosol" "HPA071516: AB_2686407" "unprognostic (1.37e-1)" "unprognostic (4.18e-1)" "unprognostic (1.53e-1)" "unprognostic (2.48e-2)" "unprognostic (7.10e-2)" "unprognostic (2.03e-2)" "unprognostic (9.10e-2)" "unprognostic (2.18e-2)" "unprognostic (3.03e-2)" "unprognostic (5.78e-2)" "unprognostic (7.06e-2)" "unprognostic (3.66e-1)" "unprognostic (5.71e-2)" "unprognostic (1.89e-2)" "unprognostic (9.48e-2)" "unprognostic (4.39e-2)" "unprognostic (2.39e-2)" 7.8 4.4 17.1 6.6 41.6 1.4 4.8 11.4 21.9 5.0 0.0 3.2 1.5 4.6 2.8 2.5 5.2 5.0 4.9 40.6 17.8 4.5 10.0 17.3 2.7 16.5 18.1 8.4 3.2 3.3 3.2 6.9 15.6 4.0 2.8 10.5 3.3 2.5 6.2 2.5 2.4 7.3 14.9 1.8 2.2 2.1 19.2 1.7 3.5 7.3 2.2 3.7 3.5 26.0 0.1 3.5 8.8 7.8 7.2 10.4 5.3 1.0 9.6 1.7 2.8 0.0 0.2 0.8 7.6 2.3 2.0 0.5 1.5 8.8 6.5 2.9 12.9 0.4 5.8 14.3 5.1 1.1 0.4 4.9 1.0 43.3 20.8 3.0 75.5 3.4 0.1 22.6 3.8 1.0 2.0 0.7 5.1 1.5 15.8 0.8 7.0 3.6 6.0 0.5 1.9 7.5 6.2 4.3 5.8 8.2 0.8 0.4 69.0 6.6 3.4 13.7 3.0 1.2 0.5 0.9 0.7 1.8 16.5 0.1 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.1 0.1 0.0 0.1 17.1 41.6 11.4 21.9 40.6 17.8 16.5 18.1 15.6 14.9 19.2 26.0 56.4 48.1 6.8 791.0 1.1 5.2 3.3 7.5 8.6 27.4 3.7 6.3 13.1 2.8 16.7 3.7 22.9 0.3 0.1 2.3 0.0 2.1 3.8 1.3 5.5 47.1 10.9 5.3 422.8 0.4 0.2 21.4 0.5 2.2 2.5 5.0 43.9 17.0 14.6 94.2 177.1 0.7 14.2 16.7 21.0 1.5 5.6 27.4 8.8 1568.3 6.1 5.4 0.0 434.3 815.3 1.2 8.0 8.2 0.2 8.2 0.0 1.8 12.2 11.4 13.1 4.2 5.8 0.6 1.9 2.3 2.7 0.0 0.6 26.2 1.5 1.8 DOK3 FLJ22570 ENSG00000146094 "Docking protein 3" Q7L591 5 177501904-177511274 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 93.6;lymphoid tissue: 118.4" "Group enriched" "Detected in many" 5 "B-cells: 31.6;granulocytes: 18.3;Hofbauer cells: 55.7;Kupffer cells: 51.1;Macrophages: 38.3;monocytes: 45.4;Plasma cells: 38.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 133.6" "Group enriched" "Detected in many" 6 "B-cells: 37.2;granulocytes: 133.6;monocytes: 77.6" "Cell line enhanced" "Detected in many" "Daudi: 124.0;HMC-1: 87.5;REH: 148.6;U-698: 122.1;U-937: 88.0" "Low region specificity" "Detected in many" HPA077312 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes NA 240000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoplasm, Cytokinetic bridge, Cytosol" "HPA077312: AB_2732339" "unprognostic (2.21e-2)" "unprognostic (1.14e-2)" "unprognostic (2.05e-2)" "unprognostic (5.74e-3)" "unprognostic (2.32e-2)" "unprognostic (1.34e-3)" "unprognostic (4.17e-2)" "unprognostic (2.20e-1)" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (1.21e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (3.82e-11)" "unprognostic (1.34e-1)" "unprognostic (7.25e-2)" "unprognostic (1.55e-1)" "unprognostic (3.78e-2)" 11.0 6.1 5.2 30.2 6.2 93.6 4.4 6.5 7.9 3.2 6.3 8.2 6.5 3.4 1.7 5.5 7.8 4.3 4.1 6.0 7.0 5.0 6.5 27.1 31.5 11.3 6.8 2.1 4.5 0.8 3.4 7.0 10.5 5.5 3.5 2.1 6.6 2.0 3.6 2.6 28.9 4.5 6.7 118.4 5.9 8.9 9.9 4.3 4.4 4.1 32.3 7.1 4.0 8.1 5.2 7.8 5.4 6.3 3.2 0.4 13.0 4.4 1.1 14.0 12.9 11.0 2.2 124.0 3.2 4.0 6.8 8.9 12.2 7.6 6.9 26.1 14.6 21.3 21.4 2.5 1.0 46.1 87.5 1.6 4.5 16.2 1.6 1.5 1.9 11.4 14.8 50.2 5.1 12.9 2.7 52.5 12.2 1.5 12.9 148.6 9.3 1.2 4.4 5.2 7.4 4.9 2.0 2.1 6.2 4.8 11.7 63.4 2.7 12.3 11.3 6.5 5.4 11.1 15.0 122.1 2.7 88.0 2.2 16.8 62.4 57.0 0.3 61.3 0.6 37.2 0.1 0.3 14.5 19.6 0.1 0.1 133.6 0.5 77.6 1.2 0.0 28.7 5.2 6.2 6.5 7.9 6.0 7.0 11.3 6.8 10.5 6.7 9.9 8.1 1.4 0.0 5.6 1.6 31.6 0.3 0.1 0.4 1.8 0.8 1.0 0.9 0.4 0.0 0.2 0.0 0.0 0.5 0.3 0.2 0.0 0.2 0.0 0.4 0.4 1.9 0.0 6.3 4.1 0.2 0.7 1.2 0.5 0.8 18.3 0.2 7.1 0.8 55.7 0.0 3.5 0.3 0.0 51.1 2.3 0.4 0.6 38.3 1.8 3.7 45.4 0.3 2.1 0.5 0.5 0.0 0.7 1.2 38.3 0.2 0.2 0.1 0.1 0.6 0.0 1.8 0.4 3.0 1.9 0.7 0.3 1.0 2.2 0.3 0.8 0.1 DONSON "B17, C21orf60, C2TA, DKFZP434M035" ENSG00000159147 "DNA replication fork stabilization factor DONSON" Q9NYP3 21 33559542-33588706 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 57.3;Erythroid cells: 42.1;Spermatocytes: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039558, HPA049033" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" Cytosol "HPA039558: AB_2676570, HPA049033: AB_2680608" "unprognostic (9.90e-3)" "unprognostic (1.01e-3)" "unprognostic (6.58e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-1)" "unprognostic (1.93e-2)" "prognostic unfavorable (8.22e-4)" "unprognostic (4.00e-2)" "unprognostic (5.93e-3)" "prognostic favorable (2.17e-4)" "unprognostic (1.25e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (0.00e+0)" "unprognostic (1.77e-2)" "unprognostic (1.66e-1)" "unprognostic (2.07e-1)" "unprognostic (8.83e-2)" 5.5 2.9 5.8 5.5 6.5 10.9 4.1 7.9 7.5 8.5 4.2 5.2 5.4 5.7 2.4 5.0 7.0 5.5 4.4 5.4 6.5 3.9 7.9 4.6 10.5 6.7 6.2 10.8 3.4 5.6 5.5 6.6 6.7 4.8 6.3 13.3 3.5 3.4 4.4 8.5 6.1 4.5 5.7 3.6 4.9 21.2 6.5 10.6 3.5 4.8 9.2 4.7 6.2 8.6 67.9 15.5 34.8 30.4 10.7 18.5 23.9 53.7 23.2 41.2 45.1 41.9 19.7 40.5 13.9 28.3 30.6 20.0 43.6 20.2 45.1 36.5 36.5 73.8 34.9 41.5 8.1 39.0 18.2 13.9 5.7 44.4 11.1 13.1 25.1 19.8 67.0 65.2 35.4 14.7 34.0 17.2 35.9 34.8 17.3 33.2 68.4 41.3 21.3 19.0 36.0 14.8 82.1 25.3 23.1 17.1 34.9 19.4 16.4 38.0 25.3 28.6 37.7 56.8 58.1 59.3 22.1 52.1 43.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 6.5 7.9 7.5 5.4 6.5 6.7 6.2 6.7 5.7 6.5 8.6 6.3 3.2 1.9 10.4 4.8 8.2 8.1 3.1 5.2 2.8 5.6 5.7 3.9 7.2 2.3 3.7 10.4 13.2 7.8 3.0 1.9 3.3 57.3 3.0 6.6 8.0 1.2 42.1 9.7 4.7 27.9 6.9 7.1 4.4 8.2 7.5 7.5 6.2 8.9 6.7 11.2 4.2 6.1 3.4 6.3 25.3 10.2 5.5 7.2 4.7 4.0 2.1 4.1 7.5 12.7 3.9 2.5 13.9 19.3 5.7 2.9 4.4 2.8 3.6 0.0 4.4 7.6 62.3 33.5 7.6 9.8 16.6 7.6 3.0 6.8 9.2 DPEP1 ENSG00000015413 "Dipeptidase 1" P16444 16 89613308-89638456 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dipeptidase, Hydrolase, Metalloprotease, Protease" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 377.4;kidney: 255.9;pancreas: 440.7" "Cell type enhanced" "Detected in many" "Peritubular cells: 1217.5;Proximal enterocytes: 4683.5;Proximal tubular cells: 829.6" "Cancer enriched" "Detected in many" 8 "colorectal cancer: 107.4" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 8.5;Hep G2: 33.1;HHSteC: 13.9;U-937: 46.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA009426, HPA012783" Enhanced Approved "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA 370000 "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Nucleoplasm, Cell Junctions" "HPA009426: AB_1847842, HPA012783: AB_1847843" "unprognostic (3.31e-2)" "unprognostic (3.86e-1)" "unprognostic (1.37e-1)" "unprognostic (1.95e-2)" "unprognostic (1.91e-2)" "unprognostic (4.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.89e-1)" "unprognostic (3.45e-2)" "unprognostic (5.18e-1)" "unprognostic (8.68e-2)" "unprognostic (1.27e-1)" "prognostic favorable (6.84e-4)" "unprognostic (6.12e-3)" "unprognostic (1.92e-1)" "unprognostic (5.23e-2)" "unprognostic (3.93e-2)" 0.6 2.3 0.0 1.8 0.0 0.4 0.5 0.0 0.2 4.1 0.0 1.7 85.5 0.6 0.9 0.3 0.6 3.9 0.3 0.0 0.3 255.9 0.5 0.9 2.8 0.2 1.1 0.8 440.7 0.0 0.5 0.8 0.6 0.5 0.5 0.3 1.2 1.0 0.0 2.2 377.4 0.3 0.3 4.5 1.6 46.5 0.9 0.9 0.8 0.0 0.9 2.2 0.9 0.0 0.0 0.9 0.2 0.0 1.7 0.2 4.4 0.0 0.0 0.0 0.0 8.5 0.2 0.0 3.0 0.0 0.0 0.0 0.2 0.0 0.0 2.2 0.6 0.0 0.0 33.1 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 1.1 1.1 3.4 0.0 0.0 0.0 3.0 0.0 0.1 0.9 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.1 1.4 0.0 0.0 0.2 0.1 0.0 46.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.2 1.1 0.6 0.3 0.9 0.0 0.1 3.2 1.8 0.0 9.2 0.5 0.0 0.0 0.0 5.8 1.7 0.0 0.3 0.0 0.6 23.9 0.0 0.2 0.0 2.0 56.7 0.5 13.2 0.2 0.2 7.0 8.9 0.0 0.3 192.1 0.8 8.9 1.1 0.1 1.3 0.7 1.1 0.0 0.5 0.0 0.3 142.3 0.0 0.3 0.3 45.2 289.8 4.8 5.4 0.0 1.0 0.1 0.0 0.0 0.1 27.4 187.4 1217.5 61.2 0.0 4683.5 829.6 0.0 0.2 6.6 0.0 0.7 17.3 2.8 0.0 0.3 0.4 2.5 0.2 151.7 0.0 DPH1 "DPH2L, DPH2L1, OVCA1" ENSG00000108963 "Diphthamide biosynthesis 1" Q9BZG8 17 2030137-2043898 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" Transferase "Disease variant, Dwarfism, Ectodermal dysplasia, Hypotrichosis, Mental retardation, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 19.4;Gastric mucus-secreting cells: 21.4;Plasma cells: 12.0;Squamous epithelial cells: 13.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069750, HPA073864" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Cell Junctions" "HPA069750: AB_2686188, HPA073864: " "unprognostic (5.54e-2)" "unprognostic (1.99e-1)" "unprognostic (1.62e-1)" "unprognostic (1.86e-2)" "unprognostic (1.50e-2)" "unprognostic (1.46e-1)" "unprognostic (2.21e-1)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "prognostic favorable (1.78e-5)" "unprognostic (2.74e-3)" "unprognostic (2.10e-2)" "unprognostic (1.03e-1)" "unprognostic (3.40e-1)" "unprognostic (7.30e-2)" "unprognostic (1.41e-1)" 24.5 32.3 13.1 6.0 12.8 5.3 22.2 16.8 17.7 29.1 10.7 26.8 8.0 28.8 5.6 19.8 31.0 9.1 19.2 13.7 11.9 28.0 36.3 16.6 7.5 10.3 10.9 26.6 32.0 14.2 59.3 8.5 10.3 36.2 6.2 12.4 23.7 11.0 42.3 29.3 20.8 8.9 10.1 24.3 27.0 20.3 11.7 6.7 28.6 13.7 6.0 24.2 22.3 11.5 15.4 24.9 6.3 16.0 22.2 14.2 18.7 19.3 26.8 29.7 18.7 24.1 11.6 29.0 23.6 52.5 11.2 11.6 20.7 21.1 15.9 9.0 52.4 6.3 10.5 13.1 19.4 8.3 10.2 20.3 20.3 22.7 19.0 20.5 13.9 16.8 23.4 11.2 11.9 18.2 14.7 4.8 6.5 17.3 25.9 16.6 5.7 22.0 13.3 8.0 13.1 15.2 17.4 17.9 17.2 6.9 25.9 6.8 10.1 19.4 10.1 26.2 16.7 10.3 8.3 6.8 20.3 10.8 8.5 0.8 4.5 0.8 8.0 6.1 8.9 8.8 6.5 7.4 7.7 7.2 9.6 6.9 0.3 6.7 4.5 5.5 10.2 5.2 13.1 12.8 16.8 17.7 13.7 11.9 10.3 10.9 10.3 10.1 11.7 11.5 0.9 3.2 9.2 1.3 9.3 0.4 0.9 0.5 19.4 2.1 0.8 0.8 1.5 0.0 2.7 0.0 2.1 1.4 0.9 0.6 0.0 0.5 1.2 1.5 1.2 1.7 0.0 9.0 4.0 0.6 0.9 4.5 21.4 0.8 2.5 1.0 0.7 0.0 0.6 1.7 3.7 0.8 0.0 0.0 0.8 1.5 0.6 3.9 0.0 1.0 0.4 0.9 2.1 1.5 1.4 0.0 0.2 0.4 12.0 0.5 0.5 0.5 3.0 2.8 0.0 1.3 3.2 1.2 0.5 13.0 0.3 1.4 5.4 1.3 0.4 0.6 DPPA5 Esg1 ENSG00000203909 "Developmental pluripotency associated 5" A6NC42 6 73353063-73354276 "Predicted intracellular proteins" "Developmental protein, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "testis: 2.1" "Group enriched" "Detected in some" 4 "Spermatocytes: 2.4;Spermatogonia: 1.4" "Cancer enriched" "Detected in single" 2209 "testis cancer: 347.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 43 "SuSa: 6.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA055016, HPA064505" Uncertain Uncertain "Cell Junctions" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Cell Junctions" "HPA055016: , HPA064505: AB_2685275" "unprognostic (1.85e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DPY19L4 ENSG00000156162 "Dpy-19 like 4" Q7Z388 8 94719703-94793836 "Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 65.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024339, HPA024780" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nuclear bodies, Cytosol" "HPA024339: , HPA024780: AB_10600869" "unprognostic (1.45e-1)" "unprognostic (2.89e-3)" "unprognostic (3.41e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.28e-1)" "unprognostic (5.54e-2)" "unprognostic (4.94e-2)" "unprognostic (7.17e-2)" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (4.72e-2)" "unprognostic (9.38e-2)" "unprognostic (2.25e-1)" "unprognostic (1.48e-2)" "unprognostic (1.74e-1)" "unprognostic (1.39e-2)" "unprognostic (1.55e-1)" 11.5 12.3 7.3 6.6 10.5 5.1 12.5 9.7 9.4 13.6 8.0 8.6 6.7 12.3 10.5 7.6 11.2 10.0 15.4 6.5 10.1 14.5 15.8 9.1 6.9 9.9 9.0 16.7 9.4 26.4 6.4 12.6 10.3 11.6 9.0 13.0 10.2 9.0 7.2 9.4 7.9 9.5 9.6 11.1 13.1 9.6 8.9 7.0 16.1 9.3 5.8 8.6 8.5 14.4 24.4 15.5 26.1 16.4 25.9 33.3 14.4 21.5 20.3 19.8 19.4 7.3 35.0 5.4 25.8 20.8 13.3 25.0 16.0 16.9 32.7 12.2 12.8 25.3 15.1 12.2 30.1 10.9 5.1 22.2 14.0 16.8 16.2 23.2 24.3 16.0 18.0 9.0 23.3 15.3 20.9 20.5 10.2 27.9 17.2 14.8 17.9 10.9 19.1 18.9 12.8 28.7 17.2 3.6 16.8 15.9 22.8 13.6 24.0 20.5 12.6 23.1 18.1 9.9 13.1 14.8 15.4 18.7 29.6 0.7 0.5 0.0 1.0 0.6 1.4 1.2 1.0 1.6 1.0 0.3 1.1 1.4 0.4 1.4 0.6 1.2 0.4 0.7 7.3 10.5 9.7 9.4 6.5 10.1 9.9 9.0 10.3 9.6 8.9 14.4 21.1 16.0 16.3 20.5 6.3 9.8 14.1 11.6 15.9 19.6 16.2 12.1 26.0 11.5 13.0 40.5 4.2 16.7 3.7 8.5 1.9 8.9 2.1 13.7 20.3 19.0 7.3 9.7 13.2 10.0 11.9 20.4 12.2 13.7 3.8 23.1 65.0 27.5 9.6 13.5 18.3 11.5 10.2 14.8 11.9 5.0 17.4 8.3 10.6 25.3 5.5 11.9 9.2 23.6 39.7 13.0 6.4 18.4 7.9 15.6 10.7 10.7 18.8 17.6 6.6 13.4 14.9 11.9 9.8 16.6 12.1 9.2 7.8 32.6 12.0 14.1 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 21.3;retina: 8.4" "Group enriched" "Detected in some" 12 "Bipolar cells: 40.1;Horizontal cells: 33.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 26.4" "Region enriched" "Detected in many" 9 "basal ganglia: 164.4" "Region enriched" "Detected in many" 13 "basal ganglia: 86.7" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Cytosol "HPA013393: AB_1847833, HPA017304: " "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" 0.4 0.6 4.7 0.0 21.3 0.0 0.2 0.0 8.5 0.4 0.1 0.2 0.1 0.1 0.2 0.3 0.2 0.4 0.0 3.1 0.4 0.7 1.1 0.7 0.0 0.3 0.9 0.1 0.0 0.0 0.1 1.1 0.0 1.1 0.3 8.4 0.0 0.4 0.0 0.0 0.3 0.1 0.7 0.1 0.2 0.0 1.8 0.3 0.1 0.6 0.1 0.7 0.4 2.9 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 26.4 0.7 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 21.3 0.0 8.5 3.1 0.4 0.3 0.9 0.0 0.7 1.8 2.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 40.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 33.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Bipolar cells: 168.8;Cone photoreceptor cells: 87.6;Rod photoreceptor cells: 206.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Centrosome "HPA062682: " "unprognostic (8.83e-2)" "unprognostic (2.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.81e-2)" "unprognostic (7.52e-2)" "unprognostic (7.89e-3)" "unprognostic (3.14e-2)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (5.07e-2)" "unprognostic (3.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-4)" "unprognostic (1.26e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-1)" 0.9 0.8 0.5 0.0 0.6 0.0 0.8 1.3 0.6 2.5 0.1 1.9 0.0 1.6 0.0 1.1 2.5 0.0 1.1 0.4 0.0 1.3 1.5 1.3 0.0 0.6 0.2 3.5 1.5 0.0 4.2 0.0 0.5 2.3 0.0 0.0 0.5 0.0 1.0 1.5 1.1 0.0 0.1 0.6 0.8 2.5 0.3 0.0 1.8 0.0 0.0 1.7 1.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.6 1.3 0.6 0.4 0.0 0.6 0.2 0.5 0.1 0.3 0.6 0.5 0.0 0.5 4.2 0.2 0.0 0.3 0.2 0.0 168.8 0.3 0.4 1.7 0.0 0.1 1.8 87.6 0.6 8.6 0.8 0.0 0.1 0.7 0.3 0.4 1.5 0.0 0.0 0.8 0.4 0.3 0.5 2.0 0.7 0.0 1.5 0.0 0.1 0.2 6.7 1.2 1.3 0.0 0.3 0.3 0.2 0.6 0.9 0.0 0.0 0.1 26.0 0.0 0.0 2.6 0.4 0.2 0.7 0.1 1.1 8.3 1.9 0.1 206.9 0.0 0.8 0.6 1.2 2.6 0.8 0.4 0.1 0.1 0.5 1.3 0.3 DRP2 ENSG00000102385 "Dystrophin related protein 2" Q13474 X 101219769-101264502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lymphoid tissue: 4.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 35.6;Inhibitory neurons: 24.5;Oligodendrocyte precursor cells: 11.1" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 10.7;TIME: 18.5;U-87 MG: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 56.0" HPA002949 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Plasma membrane" "HPA002949: AB_1078706" "unprognostic (8.47e-4)" "unprognostic (3.56e-3)" "unprognostic (1.01e-2)" "unprognostic (5.58e-4)" "unprognostic (1.74e-2)" "unprognostic (2.47e-2)" "unprognostic (7.93e-3)" "unprognostic (2.94e-3)" "unprognostic (1.27e-2)" "unprognostic (5.46e-3)" "unprognostic (1.42e-1)" "unprognostic (4.61e-2)" "unprognostic (4.44e-16)" "unprognostic (3.71e-4)" "unprognostic (4.22e-1)" "unprognostic (9.03e-2)" "unprognostic (1.25e-1)" 0.7 0.3 4.0 0.2 5.9 0.2 0.4 0.0 8.8 0.6 0.0 3.2 0.2 0.7 0.7 0.2 0.2 0.2 0.2 6.2 0.7 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 0.0 2.3 0.0 0.6 1.3 0.4 1.0 0.6 0.9 0.2 0.3 0.8 0.6 0.0 0.0 0.3 0.5 0.7 4.7 0.0 1.1 0.0 0.6 1.1 4.8 0.0 0.6 2.2 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.9 0.0 0.4 0.3 0.2 0.1 0.6 0.0 0.3 0.0 0.7 0.1 0.2 0.2 0.6 0.0 0.2 0.1 0.4 1.4 0.0 0.7 0.0 0.0 1.4 0.5 0.0 0.9 1.5 0.0 1.3 0.5 0.1 0.1 0.1 0.3 10.7 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.4 0.0 0.1 18.5 0.2 0.7 0.2 0.4 0.0 0.1 0.0 4.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 8.8 6.2 0.7 0.1 2.6 0.6 0.0 0.7 4.8 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.8 0.0 35.6 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 24.5 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.3 0.0 11.1 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DSG2 CDHF5 ENSG00000046604 "Desmoglein 2" Q14126 18 31498177-31549008 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 105.3;parathyroid gland: 157.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.6;Pancreatic endocrine cells: 254.9;Undifferentiated cells: 216.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 13 "basophil: 8.4" "Lineage enriched" "Detected in single" 13 "granulocytes: 8.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 172.9;HaCaT: 269.2;HBEC3-KT: 201.2;hTERT-HME1: 212.1;OE19: 229.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA004896, CAB025122" Enhanced Supported "Cell Junctions" NA NA 140000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "CAB025122: , HPA004896: AB_1078643" "unprognostic (1.56e-3)" "prognostic unfavorable (8.22e-4)" "prognostic favorable (7.81e-4)" "unprognostic (8.77e-3)" "unprognostic (3.53e-4)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.86e-3)" "prognostic unfavorable (2.43e-4)" "unprognostic (5.21e-2)" "unprognostic (1.49e-1)" "prognostic unfavorable (4.94e-5)" "unprognostic (3.40e-1)" "prognostic favorable (3.14e-10)" "unprognostic (1.76e-1)" "unprognostic (1.51e-1)" "unprognostic (3.72e-1)" "unprognostic (8.57e-3)" 23.6 1.2 0.2 14.6 0.2 0.8 40.2 0.6 0.2 13.0 26.4 105.3 79.1 8.6 10.6 10.2 22.4 31.4 31.4 0.7 0.1 33.8 15.1 15.0 1.6 0.3 0.5 13.6 39.5 157.8 1.6 22.9 0.7 31.5 100.0 0.3 68.6 6.5 1.2 6.7 84.6 7.3 0.0 0.4 77.1 3.7 0.4 24.2 42.2 0.7 4.6 41.6 5.7 0.5 119.2 45.3 4.0 0.1 0.6 7.2 143.0 0.0 0.0 0.3 0.0 31.7 172.9 0.0 64.2 0.0 54.4 269.2 54.7 201.2 0.0 0.2 33.9 0.1 46.7 35.9 20.2 15.2 0.3 9.9 136.7 4.2 212.1 102.4 0.0 34.7 47.8 0.2 0.0 31.5 32.2 2.0 55.4 229.5 23.1 52.8 0.0 76.2 65.8 58.5 23.9 0.2 88.3 61.8 0.3 117.8 44.3 12.7 0.1 0.2 25.0 0.3 29.3 5.7 0.2 0.2 19.8 0.1 25.3 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.2 0.2 0.6 0.2 0.7 0.1 0.3 0.5 0.7 0.0 0.4 0.5 120.8 54.5 45.4 0.0 1.3 13.5 79.4 76.2 28.5 0.4 68.9 49.3 57.3 101.5 79.6 12.9 0.0 80.1 4.4 404.6 3.9 105.5 1.0 48.6 9.4 13.1 79.9 9.0 3.3 76.1 116.2 12.0 70.3 82.1 4.5 18.8 2.2 26.4 10.3 1.7 0.3 165.7 79.3 0.8 4.0 2.5 1.5 2.2 17.8 0.0 6.3 5.3 1.0 0.5 0.1 254.9 152.0 0.4 0.3 133.5 145.1 10.0 75.4 0.7 0.0 0.6 8.2 2.7 8.9 23.1 6.0 59.9 2.6 6.6 216.8 179.9 DSP "DPI, DPII, KPPS2, PPKS2" ENSG00000096696 Desmoplakin P15924 6 7541617-7586714 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cardiomyopathy, Disease variant, Epidermolysis bullosa, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 460.7;skin 1: 854.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 902.0;Cardiomyocytes: 729.7;Squamous epithelial cells: 1657.5;Suprabasal keratinocytes: 2018.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 314.1" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 13 "naive B-cell: 2.0" "Lineage enriched" "Detected in single" 20 "B-cells: 2.0" "Cell line enhanced" "Detected in many" "BEWO: 278.0;HaCaT: 302.6;HBEC3-KT: 217.5;hTCEpi: 666.3;SuSa: 204.1" "Region enriched" "Detected in single" 23 "hippocampal formation: 11.6" "Region enhanced" "Detected in many" "spinal cord: 9.5" "CAB037324, HPA045840, HPA054950" Enhanced Supported "Cell Junctions" NA NA 100000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "CAB037324: , HPA045840: AB_2679468, HPA054950: AB_2682645" "unprognostic (1.65e-1)" "unprognostic (3.09e-1)" "unprognostic (6.13e-2)" "unprognostic (1.05e-2)" "unprognostic (1.09e-1)" "unprognostic (2.05e-2)" "unprognostic (3.82e-2)" "unprognostic (7.03e-3)" "unprognostic (1.28e-1)" "unprognostic (2.64e-2)" "unprognostic (5.02e-2)" "unprognostic (2.94e-2)" "prognostic favorable (1.53e-9)" "unprognostic (2.45e-1)" "unprognostic (2.88e-1)" "unprognostic (8.38e-2)" "prognostic unfavorable (1.82e-4)" 5.2 11.6 4.2 7.0 1.8 0.6 65.8 2.5 3.5 151.0 19.3 46.0 52.0 5.4 27.5 460.7 16.3 7.8 84.9 3.4 0.9 22.4 41.9 6.1 3.7 1.6 2.0 2.0 111.5 54.9 9.0 63.3 1.5 29.9 43.5 21.2 125.1 11.7 3.4 854.8 42.3 2.9 2.4 3.2 48.1 1.5 2.2 37.1 41.5 0.6 78.7 13.1 286.1 0.9 132.2 38.9 0.0 0.1 5.6 8.2 278.0 25.5 21.8 12.4 12.0 110.8 33.5 0.1 35.8 40.9 10.0 302.6 46.1 217.5 2.2 0.1 54.1 0.0 21.5 149.5 0.0 0.6 0.9 1.9 666.3 11.0 121.7 30.0 0.0 0.6 0.2 0.2 22.0 61.4 0.1 1.0 5.6 62.6 19.6 0.1 0.1 32.9 45.3 34.8 12.6 0.3 28.5 59.9 0.2 204.1 71.0 0.3 0.0 4.8 1.2 0.3 0.3 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.8 2.5 3.5 3.4 0.9 1.6 2.0 1.5 2.4 2.2 0.9 7.6 51.3 17.0 0.0 7.5 902.0 164.5 157.3 278.3 4.4 184.5 126.4 729.7 97.2 197.5 60.7 14.6 273.0 1.2 357.1 1.9 160.6 1.8 306.5 42.4 46.9 174.6 0.0 0.1 111.9 273.1 51.2 237.0 560.1 3.8 532.2 4.6 186.6 27.5 0.0 0.9 204.7 111.9 1.9 77.8 1.3 0.9 5.9 101.4 3.7 2.6 14.7 0.0 0.0 0.1 167.4 284.2 0.0 5.7 204.0 180.7 12.0 176.6 28.6 0.0 0.4 67.4 1.3 2.7 1657.5 2018.0 385.7 8.1 0.3 247.8 269.9 DTNA "D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3" ENSG00000134769 "Dystrobrevin alpha" Q9Y4J8 18 34493290-34891844 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "brain: 461.9;choroid plexus: 120.6;heart muscle: 150.0;skeletal muscle: 166.9;tongue: 209.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1756.1;Excitatory neurons: 506.0;Inhibitory neurons: 650.9;Oligodendrocyte precursor cells: 491.6;Oligodendrocytes: 367.4" "Cancer enriched" "Detected in many" 9 "glioma: 28.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 37.7;NTERA-2: 42.0;SCLC-21H: 51.9;U-87 MG: 52.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015196, HPA071177" Enhanced Approved "Nucleoplasm,Cell Junctions,Intermediate filaments" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions, Intermediate filaments" Nucleoplasm "CAB015196: AB_2261797, HPA071177: " "unprognostic (1.57e-1)" "unprognostic (4.57e-2)" "unprognostic (3.13e-3)" "unprognostic (7.82e-6)" "unprognostic (5.03e-1)" "unprognostic (2.43e-3)" "unprognostic (2.73e-1)" "unprognostic (7.42e-2)" "unprognostic (1.23e-1)" "unprognostic (6.27e-2)" "unprognostic (1.35e-4)" "unprognostic (6.89e-2)" "prognostic favorable (2.64e-7)" "unprognostic (6.08e-3)" "unprognostic (3.93e-2)" "unprognostic (1.12e-1)" "unprognostic (7.27e-5)" 11.6 6.6 252.7 5.4 248.2 0.8 9.6 243.3 260.1 5.4 120.6 22.4 3.9 8.1 20.5 22.9 11.7 9.4 150.0 250.1 423.0 2.3 2.2 6.6 2.3 461.9 326.9 7.0 18.1 2.4 10.8 4.1 360.4 23.6 7.6 19.8 11.3 25.3 166.9 2.7 8.4 19.4 308.1 4.8 6.8 6.1 269.2 0.5 12.3 209.9 2.0 32.0 5.2 331.0 0.7 0.5 17.3 0.0 9.5 25.1 2.6 3.2 14.8 0.6 1.7 3.8 0.2 0.1 8.9 1.9 15.3 1.1 2.1 7.5 1.8 0.0 10.7 0.1 0.9 5.7 7.1 0.2 0.2 19.2 1.8 11.9 4.5 14.2 6.7 0.1 2.4 1.9 3.8 37.7 0.1 0.2 42.0 0.6 8.1 0.1 7.7 24.1 0.9 0.3 51.9 6.9 0.0 1.7 4.9 23.8 21.8 6.3 0.5 16.7 9.9 0.3 5.2 1.3 2.0 1.0 52.5 0.0 8.4 1.0 0.7 0.0 0.8 0.0 1.1 0.8 1.5 1.1 3.5 0.7 1.6 1.3 0.3 0.8 0.0 0.1 4.3 1.0 252.7 248.2 243.3 260.1 250.1 423.0 461.9 326.9 360.4 308.1 269.2 331.0 5.1 0.0 1.1 1756.1 0.1 1.5 0.1 0.8 0.0 18.3 22.2 12.3 134.3 27.1 1.4 0.0 6.2 0.1 0.4 0.0 5.9 12.6 3.1 7.0 2.6 6.4 0.0 0.0 506.0 25.1 0.1 5.7 0.0 0.4 0.0 2.3 0.0 0.2 9.0 1.7 650.9 0.1 4.1 4.0 21.5 3.7 5.9 8.0 5.4 105.9 0.9 34.0 0.0 491.6 367.4 8.0 0.0 0.4 0.0 1.8 0.1 2.0 7.1 3.8 13.1 22.7 17.3 0.9 4.8 0.2 1.0 0.0 0.2 0.3 0.2 0.2 DUS1L "DUS1, PP3111" ENSG00000169718 "Dihydrouridine synthase 1 like" Q6P1R4 17 82057506-82065887 "Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023384 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA023384: AB_1847879" "unprognostic (4.42e-2)" "unprognostic (2.19e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-2)" "unprognostic (1.73e-3)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (5.17e-2)" "unprognostic (1.10e-1)" "unprognostic (4.16e-3)" "unprognostic (5.23e-3)" "unprognostic (3.13e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (4.17e-2)" "unprognostic (8.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.70e-3)" 83.3 86.7 38.2 51.1 38.0 94.2 89.0 35.2 49.7 85.3 40.6 101.3 66.6 74.0 23.0 117.8 81.8 27.0 93.1 38.4 34.9 90.4 174.3 80.5 64.8 40.4 36.4 82.3 148.3 32.0 99.7 27.0 37.0 118.8 29.8 16.9 105.8 30.4 144.3 127.1 107.2 18.9 35.2 131.3 119.4 93.6 38.5 37.7 93.6 27.3 33.3 87.9 85.0 38.6 169.4 109.0 37.7 44.3 28.9 28.4 115.0 57.5 26.8 56.5 40.2 99.7 77.9 133.7 65.3 33.0 39.8 112.0 46.1 60.9 21.9 54.6 263.1 89.2 167.3 178.8 65.3 138.8 101.0 43.1 75.1 37.3 46.4 27.0 64.1 124.8 147.1 69.4 28.5 268.6 192.9 114.9 43.7 87.6 151.7 143.7 43.1 151.7 42.3 114.3 193.9 118.7 45.2 192.6 127.1 35.8 112.3 133.1 49.1 91.7 89.0 79.3 150.1 164.5 48.9 113.0 58.8 102.2 65.0 3.0 3.5 5.0 4.0 3.9 6.0 3.9 4.0 5.0 3.6 3.3 6.5 5.6 1.2 5.9 5.3 7.9 7.6 2.0 38.2 38.0 35.2 49.7 38.4 34.9 40.4 36.4 37.0 35.2 38.5 38.6 36.8 28.9 19.1 17.6 30.0 22.0 20.0 10.0 10.8 28.3 78.3 69.8 21.3 24.3 15.0 11.0 29.2 16.1 60.1 65.2 7.9 12.1 87.2 30.5 28.4 21.0 43.2 21.7 15.9 39.1 19.1 19.1 37.2 37.6 3.8 46.3 13.9 77.8 21.0 18.5 15.8 58.1 8.2 26.8 14.3 146.2 14.3 27.0 10.6 10.3 19.2 17.8 27.8 10.1 18.2 32.0 32.2 13.5 33.7 40.9 32.4 24.5 15.3 47.8 13.1 18.0 23.9 43.3 9.6 23.3 28.4 15.6 28.4 52.2 75.4 37.5 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 210.5" "Group enriched" "Detected in many" 4 "Distal tubular cells: 273.9;Early spermatids: 288.8;Late spermatids: 979.4" "Cancer enhanced" "Detected in many" "renal cancer: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.8;REH: 16.0;SH-SY5Y: 4.3;SK-MEL-30: 4.0;U-2 OS: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA076649: AB_2686811" "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favorable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.7 5.9 5.3 0.2 7.6 0.1 3.4 10.7 7.5 5.9 4.9 1.8 0.5 3.4 9.0 1.0 1.5 0.7 7.8 4.8 7.7 50.0 0.7 1.6 0.6 17.1 8.7 5.2 2.4 13.0 8.7 0.7 8.1 6.6 0.1 0.6 2.1 3.0 0.9 1.2 1.5 0.3 7.8 2.7 2.3 210.5 7.6 0.3 9.6 0.3 0.2 2.5 2.7 8.8 0.2 0.2 0.1 1.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 4.8 0.1 1.0 1.9 0.2 2.6 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 3.4 0.6 0.0 0.0 16.0 1.8 0.1 0.0 0.0 2.1 4.3 2.6 0.0 4.0 0.1 1.1 0.9 0.0 0.0 3.6 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.6 10.7 7.5 4.8 7.7 17.1 8.7 8.1 7.8 7.6 8.8 2.9 0.0 0.0 1.3 0.8 0.6 1.3 0.0 0.0 0.6 3.6 4.4 2.5 1.5 0.0 18.4 4.2 0.0 0.4 0.1 273.9 2.4 288.8 0.6 4.0 2.2 1.8 0.0 1.7 1.0 0.1 2.9 1.5 0.6 0.0 7.0 1.8 0.1 0.6 6.7 2.6 0.4 0.0 0.6 1.9 979.4 8.7 1.2 7.2 0.0 0.6 2.9 0.0 3.0 4.7 0.6 0.0 10.9 0.0 0.9 0.0 55.3 0.1 0.3 0.0 2.5 3.3 121.5 6.0 0.3 0.1 0.1 0.3 7.5 0.7 0.4 DXO DOM3Z ENSG00000204348 "Decapping exoribonuclease" O77932 6 31969810-31972290 "Predicted intracellular proteins" "Exonuclease, Hydrolase, Nuclease, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 467.9;Late spermatids: 242.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046708 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA046708: AB_2679764" "unprognostic (4.56e-2)" "unprognostic (2.21e-1)" "unprognostic (1.80e-1)" "unprognostic (4.07e-3)" "unprognostic (1.93e-1)" "unprognostic (2.00e-3)" "unprognostic (3.43e-3)" "unprognostic (4.18e-3)" "unprognostic (3.10e-2)" "unprognostic (2.64e-3)" "prognostic favorable (5.87e-4)" "unprognostic (4.29e-2)" "prognostic unfavorable (4.77e-6)" "unprognostic (9.17e-2)" "unprognostic (7.24e-2)" "unprognostic (2.01e-1)" "unprognostic (2.23e-3)" 6.6 17.8 8.2 3.9 8.1 1.4 6.9 8.2 8.5 10.7 9.6 7.1 4.5 8.1 5.8 5.7 8.5 4.2 9.6 8.1 8.4 12.3 13.0 6.4 4.6 9.3 8.6 13.4 10.8 11.8 13.0 4.4 8.7 10.3 3.9 4.8 6.7 6.0 5.3 4.9 5.8 4.8 8.6 9.7 8.6 31.3 8.3 7.0 11.5 7.1 3.0 7.9 7.4 8.5 12.9 6.3 5.8 23.1 9.5 6.4 6.7 7.5 12.0 16.2 15.5 7.6 5.9 5.2 8.5 16.6 5.2 8.7 10.1 16.8 9.4 9.6 12.9 9.3 15.8 16.4 18.7 0.0 4.6 9.7 16.3 10.5 13.5 9.9 21.3 6.6 8.3 11.9 9.8 14.7 1.5 11.1 4.4 8.4 1.3 4.0 4.1 8.2 21.2 4.5 30.1 17.0 6.6 7.3 16.9 4.1 0.0 14.8 7.0 4.7 12.6 4.6 12.3 9.1 9.4 10.2 4.6 14.4 5.2 0.0 1.9 1.0 2.2 1.6 3.9 2.4 2.3 1.4 4.3 2.1 1.6 2.3 0.3 2.1 1.4 1.3 1.6 1.8 8.2 8.1 8.2 8.5 8.1 8.4 9.3 8.6 8.7 8.6 8.3 8.5 11.2 6.4 9.6 11.8 16.8 8.5 15.3 14.3 19.9 13.3 13.6 11.4 7.1 11.5 10.5 3.7 16.7 14.5 14.1 5.0 19.6 8.4 467.9 9.3 10.6 9.8 16.2 4.4 4.4 12.6 9.5 10.9 15.8 8.7 6.3 12.1 8.6 10.9 6.6 5.0 6.2 9.0 12.2 5.9 4.9 242.8 17.7 6.9 12.4 1.9 4.3 16.0 11.3 7.5 6.6 6.9 10.5 12.4 14.7 10.8 10.6 13.3 8.9 15.6 13.1 7.1 14.3 78.4 16.1 11.8 5.5 20.1 15.4 22.6 8.3 11.5 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 ECSCR "ARIA, ECSM2" ENSG00000249751 "Endothelial cell surface expressed chemotaxis and apoptosis regulator" Q19T08 5 139448560-139462743 "Predicted membrane proteins" "Angiogenesis, Apoptosis, Chemotaxis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 12 "Adipocytes: 235.8;Endothelial cells: 214.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 122 "EFO-21: 172.1;HUVEC TERT2: 443.7;TIME: 330.9" HPA063337 Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA063337: AB_2732701" "unprognostic (5.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.95e-2)" "unprognostic (2.83e-2)" "unprognostic (3.69e-2)" "unprognostic (2.15e-3)" "unprognostic (3.95e-2)" "unprognostic (1.12e-1)" "unprognostic (2.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.78e-2)" "unprognostic (1.91e-1)" "unprognostic (1.83e-3)" "unprognostic (2.41e-3)" "unprognostic (1.36e-1)" "unprognostic (9.90e-2)" "unprognostic (2.91e-1)" 62.7 12.7 5.5 11.2 5.5 0.2 59.8 5.7 8.5 26.8 5.3 19.4 4.6 29.4 7.4 15.9 33.5 12.1 54.6 5.2 5.9 29.9 6.0 60.1 11.6 6.0 5.9 10.4 6.7 4.7 7.1 33.5 6.3 19.6 8.0 0.8 16.1 7.3 15.1 16.6 20.7 24.4 6.1 23.5 15.2 3.3 6.7 3.5 40.9 17.2 7.2 35.5 26.1 5.9 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 172.1 0.3 0.1 0.0 0.0 0.0 0.6 1.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 443.7 0.1 0.0 0.0 1.4 0.0 0.0 0.9 2.5 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 330.9 0.4 0.4 0.0 1.7 0.0 0.0 0.2 0.0 1.5 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 5.5 5.7 8.5 5.2 5.9 6.0 5.9 6.3 6.1 6.7 5.9 235.8 0.0 3.9 0.0 1.0 14.9 0.4 0.0 0.0 0.0 1.9 2.5 0.0 0.0 0.6 0.0 0.0 0.2 1.0 0.0 0.0 0.6 0.0 0.4 0.5 214.9 0.0 0.0 0.1 1.2 0.1 3.1 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 18.3 0.0 0.0 1.7 10.6 5.6 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.5 0.0 0.0 0.7 0.4 0.0 0.0 1.9 0.0 0.0 0.0 13.9 0.3 1.3 0.9 0.0 1.6 EDA2R "EDA-A2R, EDAA2R, TNFRSF27, XEDAR" ENSG00000131080 "Ectodysplasin A2 receptor" Q9HAV5 X 66595637-66639298 "Predicted membrane proteins" Differentiation "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 8.3;Microglial cells: 5.6;Oligodendrocytes: 6.4;Theca cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 24.3;HSkMC: 33.3;LHCN-M2: 31.8;SuSa: 25.2" "Not detected" "Not detected" HPA054522 Approved "Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" "Cell Junctions" "HPA054522: AB_2682516" "unprognostic (1.31e-3)" "unprognostic (3.17e-3)" "unprognostic (2.19e-1)" "unprognostic (8.49e-3)" "unprognostic (4.15e-3)" "unprognostic (3.63e-3)" "unprognostic (2.48e-2)" "unprognostic (3.37e-2)" "unprognostic (2.82e-1)" "unprognostic (7.17e-2)" "unprognostic (6.04e-2)" "unprognostic (2.74e-1)" "unprognostic (1.01e-1)" "unprognostic (2.12e-2)" "unprognostic (8.23e-2)" "unprognostic (4.92e-2)" "unprognostic (3.08e-1)" 2.1 5.7 1.7 0.5 2.4 0.0 3.0 1.9 2.1 6.1 3.8 2.2 0.3 5.7 4.2 2.4 4.3 3.3 2.1 1.7 1.8 1.2 0.8 2.6 0.5 2.5 1.8 7.5 3.1 3.0 3.4 1.1 2.7 4.0 4.9 0.7 2.5 5.4 2.4 1.5 1.1 5.2 2.2 1.2 0.8 1.4 2.3 2.6 5.6 0.9 0.4 2.4 4.3 3.7 0.0 16.4 15.0 0.0 21.0 24.3 0.2 22.5 24.0 2.1 3.3 0.0 0.0 8.3 0.0 14.6 0.0 0.1 0.0 8.6 7.3 0.0 7.8 0.0 0.5 11.0 3.7 0.0 0.1 33.3 20.0 16.4 15.1 20.2 0.5 0.4 0.8 8.4 31.8 1.9 0.4 0.0 5.6 0.0 0.0 0.0 2.0 0.0 1.5 0.0 0.0 2.7 0.0 0.0 0.0 25.2 0.5 0.3 17.3 0.0 12.0 0.0 0.2 0.0 0.1 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.4 1.9 2.1 1.7 1.8 2.5 1.8 2.7 2.2 2.3 3.7 0.5 3.2 0.0 0.7 0.8 0.3 1.0 1.5 2.8 0.1 1.2 1.7 0.5 1.5 1.4 1.8 0.0 1.2 0.1 0.0 0.0 0.2 0.0 0.5 1.2 0.6 1.2 0.0 0.0 0.6 1.3 2.5 0.5 0.2 0.0 8.3 0.7 0.0 0.2 0.0 0.3 0.5 2.0 0.0 0.3 0.0 1.8 0.1 1.8 5.6 0.0 1.5 1.0 2.0 6.4 0.6 0.3 0.4 0.0 1.1 0.2 0.4 1.0 0.0 0.0 3.6 1.6 0.0 0.2 0.7 0.6 0.7 0.6 5.0 0.5 0.6 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EEF1AKMT1 N6AMT2 ENSG00000150456 "EEF1A lysine methyltransferase 1" Q8WVE0 13 20728731-20773961 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Breast myoepithelial cells: 19.9;Cytotrophoblasts: 19.8;Distal tubular cells: 27.4;Endometrial ciliated cells: 20.9;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040417, HPA042543" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA040417: AB_2676973, HPA042543: AB_2678045" "unprognostic (4.14e-1)" "unprognostic (5.11e-2)" "unprognostic (8.57e-2)" "prognostic favorable (1.82e-4)" "unprognostic (9.14e-2)" "unprognostic (3.44e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (1.51e-2)" "unprognostic (1.39e-1)" "unprognostic (2.39e-3)" "unprognostic (3.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.81e-2)" "unprognostic (4.31e-2)" 9.6 10.3 11.1 5.3 11.6 3.4 9.8 11.8 16.8 11.2 10.5 9.5 4.5 10.8 14.3 5.8 11.1 6.3 9.9 11.2 12.6 9.5 13.5 6.4 6.8 11.1 11.6 10.4 6.3 9.5 9.9 6.5 11.8 10.2 6.0 10.2 7.9 8.9 11.1 5.9 5.6 9.2 12.0 5.8 7.1 4.3 12.0 9.2 9.5 12.2 6.8 8.8 7.5 12.3 11.1 8.5 6.9 11.4 28.3 29.2 16.9 14.4 11.0 12.4 6.4 11.9 12.1 18.0 10.5 15.8 5.8 9.0 9.4 12.2 12.8 11.7 8.4 23.3 3.8 22.8 15.6 46.3 4.6 20.1 10.7 9.2 20.4 13.8 22.4 15.7 13.6 2.4 35.5 30.7 15.6 41.0 12.0 20.2 6.2 19.2 7.6 3.5 17.8 12.7 15.8 9.4 12.5 6.1 16.5 5.9 6.4 42.4 13.3 8.5 0.0 19.1 6.4 3.3 6.7 19.9 7.3 31.4 6.1 0.0 5.2 0.9 8.6 4.1 9.6 13.1 10.3 9.0 8.9 5.4 13.0 11.3 0.7 16.3 4.4 10.8 12.0 6.7 11.1 11.6 11.8 16.8 11.2 12.6 11.1 11.6 11.8 12.0 12.0 12.3 15.0 22.4 9.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.3 19.9 0.0 0.0 8.1 7.3 0.0 19.8 3.1 0.0 27.4 12.6 0.0 20.9 16.2 6.0 0.0 0.0 0.0 10.4 15.2 8.9 0.0 7.0 3.8 13.2 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.4 0.0 0.0 36.5 7.3 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 15.7 2.2 9.9 0.0 0.0 EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985463 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 17000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB007795: AB_598149, HPA040534: AB_2677024, HPA057351: AB_2683417" "unprognostic (5.47e-2)" "unprognostic (9.59e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.81e-6)" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-1)" "unprognostic (1.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.25e-5)" "unprognostic (4.46e-2)" "unprognostic (5.60e-2)" "unprognostic (6.82e-2)" "unprognostic (9.86e-2)" 1022.6 1037.0 771.8 507.3 755.2 920.3 946.7 737.2 1059.6 966.7 807.6 1122.4 821.4 887.6 563.7 1062.3 857.3 501.2 1396.6 740.9 729.1 843.2 1152.9 666.9 685.4 775.4 769.6 1627.6 3194.1 494.0 838.0 386.2 782.3 819.2 344.5 224.7 1276.4 500.3 2322.6 1142.7 798.9 385.4 758.3 721.6 1266.6 490.5 762.7 541.0 793.6 1112.4 499.0 927.8 797.7 745.1 1456.8 1018.4 579.3 1539.4 1515.6 2706.7 830.9 1110.4 1479.8 1036.7 1012.7 1618.1 652.7 3000.6 644.1 1032.3 461.1 1069.8 919.4 1719.4 544.2 755.0 1533.0 768.5 919.9 1677.0 2204.8 1668.0 1277.6 3515.5 1777.2 916.0 1404.1 1497.5 1086.6 1434.4 1526.7 2145.4 642.1 2095.7 1510.1 1266.3 1537.0 518.3 1015.7 1654.2 860.3 1938.3 871.2 1270.2 1575.4 1466.4 699.0 1377.1 2058.3 543.1 1344.7 1992.7 1321.8 738.2 765.7 1521.4 1738.7 2276.4 1644.3 1485.3 1100.4 2065.8 986.6 81.2 455.7 64.1 259.8 333.1 460.2 578.5 453.0 344.6 430.7 478.1 497.2 404.1 43.1 355.3 342.1 358.7 429.4 756.5 771.8 755.2 737.2 1059.6 740.9 729.1 775.4 769.6 782.3 758.3 762.7 745.1 323.1 221.2 392.2 24.5 1125.5 1321.1 1071.3 754.3 1269.7 212.6 981.3 694.3 627.9 597.7 448.3 255.6 77.2 958.1 535.9 556.9 986.1 716.0 799.2 318.2 675.4 568.2 744.2 934.8 23.2 1816.8 1305.0 679.7 619.3 428.5 373.4 596.1 656.8 690.6 610.1 203.6 28.9 982.1 411.0 885.4 859.5 1195.6 1008.4 514.2 645.7 36.5 907.5 429.1 614.8 27.2 42.2 868.2 815.5 832.8 992.8 1010.5 1562.7 1078.8 194.5 134.1 585.1 797.7 697.3 371.5 308.4 1343.0 1347.1 1243.1 727.1 1044.3 1168.4 1051.6 EFCAB1 FLJ11767 ENSG00000034239 "EF-hand calcium binding domain 1" Q9HAE3 8 48710789-48735311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 91.6;testis: 37.5" "Group enriched" "Detected in many" 19 "Early spermatids: 538.8;Endometrial ciliated cells: 159.1;Late spermatids: 552.0;Respiratory ciliated cells: 310.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 6.5;ASC diff: 2.6;ASC TERT1: 6.2;CAPAN-2: 3.1;hTEC/SVTERT24-B: 2.6;SCLC-21H: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023527, HPA069955" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Plasma membrane" "HPA023527: AB_2231065, HPA069955: AB_2686220" "unprognostic (5.29e-3)" "unprognostic (7.39e-3)" "unprognostic (1.05e-1)" "unprognostic (2.67e-3)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (9.81e-2)" "unprognostic (1.62e-1)" "unprognostic (2.52e-2)" "unprognostic (1.85e-1)" "unprognostic (5.94e-3)" "unprognostic (7.81e-2)" "unprognostic (4.87e-3)" "unprognostic (4.81e-2)" "unprognostic (1.99e-1)" "unprognostic (2.51e-1)" "unprognostic (3.47e-3)" 0.3 1.5 3.1 0.1 4.7 0.7 3.0 1.9 2.5 11.4 22.4 0.5 0.6 12.4 2.5 0.7 91.6 0.6 0.2 3.7 4.9 0.5 0.7 10.6 0.1 13.5 12.1 19.3 3.2 0.0 3.1 0.5 7.0 5.4 0.4 0.0 2.0 5.9 0.0 4.7 1.0 2.9 9.1 0.3 0.6 37.5 5.7 0.4 0.1 0.2 0.2 2.3 3.4 8.5 6.5 0.0 0.8 0.0 2.6 6.2 0.0 0.1 0.6 0.0 0.2 0.0 3.1 0.0 0.0 0.1 0.0 1.7 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.1 0.2 2.6 1.1 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.5 4.9 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.1 0.0 1.2 0.3 0.0 0.0 0.1 0.0 3.1 4.7 1.9 2.5 3.7 4.9 13.5 12.1 7.0 9.1 5.7 8.5 0.4 0.0 5.9 0.0 0.0 6.8 9.7 14.7 4.0 0.0 0.4 9.1 0.4 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.0 0.3 538.8 159.1 4.7 1.2 0.0 0.0 0.7 1.5 0.1 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 10.2 0.0 0.3 552.0 4.7 0.8 1.8 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 5.7 0.0 3.4 0.0 0.3 310.7 0.0 0.0 0.7 6.2 16.9 4.5 0.1 1.8 0.3 0.4 3.9 0.0 2.5 EFCAB11 C14orf143 ENSG00000140025 "EF-hand calcium binding domain 11" Q9BUY7 14 89794669-89954777 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 36.8" "Group enriched" "Detected in many" 5 "Early spermatids: 557.0;Late spermatids: 363.3;Oligodendrocytes: 139.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 14.9" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA051209 Approved "Cell Junctions,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" "Cell Junctions, Cytosol" "HPA051209: AB_2681389" "unprognostic (1.03e-1)" "unprognostic (6.10e-3)" "unprognostic (2.36e-2)" "unprognostic (2.00e-3)" "unprognostic (2.39e-1)" "unprognostic (3.74e-3)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (1.00e-2)" "unprognostic (3.37e-2)" "unprognostic (1.77e-1)" "unprognostic (2.24e-1)" "unprognostic (3.84e-7)" "unprognostic (4.16e-2)" "unprognostic (1.95e-1)" "unprognostic (9.82e-2)" "unprognostic (8.45e-2)" 5.0 4.1 8.5 3.2 8.1 6.1 9.1 8.2 10.6 5.3 9.9 5.4 5.1 3.8 6.4 4.8 11.0 3.4 2.6 7.3 7.2 7.6 6.0 3.2 3.7 8.1 8.3 4.8 4.8 8.2 3.3 6.4 7.6 5.2 5.4 6.2 4.7 5.0 2.0 3.3 3.8 3.8 7.6 3.5 4.6 36.8 8.3 4.4 7.8 2.4 4.8 4.7 3.0 8.6 8.4 12.7 11.0 13.5 6.5 7.1 30.5 12.1 10.9 16.1 11.2 15.2 29.1 13.1 22.4 8.1 11.4 17.9 9.3 24.2 23.1 14.9 6.1 9.4 11.0 24.6 1.5 12.1 22.0 4.9 5.9 10.5 11.9 9.2 13.6 13.8 10.0 12.5 19.3 43.4 9.0 16.3 4.7 34.3 22.7 10.3 17.1 9.6 15.2 23.0 4.5 7.7 15.3 27.9 14.5 22.4 22.7 8.6 11.5 8.7 11.9 9.3 12.0 7.6 23.2 23.0 12.7 5.7 16.1 14.9 1.1 3.0 0.4 2.5 0.2 2.2 0.7 0.8 1.8 2.4 1.1 1.1 2.7 2.9 5.0 1.6 1.0 0.6 8.5 8.1 8.2 10.6 7.3 7.2 8.1 8.3 7.6 7.6 8.3 8.6 5.8 0.0 1.1 30.3 6.2 5.1 7.0 14.2 2.2 8.6 8.8 7.9 4.2 11.5 9.7 18.4 2.1 15.7 3.0 3.3 9.8 12.1 557.0 37.7 6.3 7.4 0.0 9.5 16.8 16.9 28.9 6.3 1.5 10.5 5.1 8.0 6.4 6.3 11.7 3.3 19.1 6.1 10.2 4.0 6.6 363.3 5.6 5.7 3.6 18.7 8.0 6.8 2.1 40.2 139.9 6.5 9.7 7.5 6.4 2.6 3.6 20.4 47.7 13.2 0.0 5.3 6.0 62.8 14.7 5.4 3.3 7.7 2.5 10.2 12.2 5.9 EFCAB2 "CFAP200, DRC8, MGC12458" ENSG00000203666 "EF-hand calcium binding domain 2" Q5VUJ9 1 244969705-245127164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 112.3;Endometrial ciliated cells: 103.1;Late spermatids: 132.5;Respiratory ciliated cells: 177.2;Spermatocytes: 115.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 77.1;THP-1: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031206, HPA031207" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA031206: AB_10599710, HPA031207: AB_10599946" "unprognostic (1.36e-2)" "unprognostic (9.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.21e-1)" "unprognostic (4.47e-2)" "unprognostic (9.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.02e-1)" "unprognostic (4.34e-3)" "unprognostic (8.41e-2)" "unprognostic (1.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.51e-4)" "unprognostic (4.88e-2)" 13.0 10.6 11.5 6.7 13.8 14.4 16.0 14.4 21.9 8.7 26.7 6.8 3.3 21.2 17.5 10.5 36.1 14.7 15.0 11.4 14.4 11.1 5.6 12.6 9.6 18.1 16.9 11.3 9.0 15.4 8.5 16.8 13.9 8.9 12.4 17.7 8.8 13.1 19.7 6.9 7.4 11.4 14.9 7.5 12.4 28.0 12.9 7.4 26.8 7.5 10.7 8.2 4.9 16.3 7.3 9.1 20.3 5.2 7.2 16.7 24.7 9.2 9.7 11.5 10.6 23.5 19.5 25.3 19.2 11.6 12.2 5.7 8.2 5.3 7.1 2.7 5.0 12.4 41.3 10.7 15.2 12.8 77.1 14.6 11.0 15.5 14.4 13.7 18.0 0.7 48.0 20.1 10.0 7.6 2.6 34.6 26.0 10.4 6.9 48.4 3.1 6.8 29.0 12.3 15.9 21.4 16.0 6.1 13.6 22.7 5.9 70.5 2.8 14.1 5.3 7.9 33.7 6.9 12.4 17.2 11.2 35.9 11.7 0.9 1.3 2.3 0.4 1.4 0.5 3.1 0.5 0.3 4.3 3.3 0.4 0.4 3.8 2.3 1.1 8.7 0.6 1.0 11.5 13.8 14.4 21.9 11.4 14.4 18.1 16.9 13.9 14.9 12.9 16.3 13.3 3.2 14.5 76.0 11.5 5.1 11.8 17.2 10.2 12.6 11.6 11.0 58.6 8.6 23.0 23.9 14.6 16.3 9.3 5.4 50.9 8.2 112.3 103.1 18.5 11.7 18.8 17.2 54.6 10.8 46.3 15.5 11.2 11.1 0.0 13.6 12.5 7.3 11.2 5.0 90.3 6.5 22.4 21.3 6.5 132.5 9.0 13.2 7.2 42.2 6.6 19.2 1.0 74.9 75.9 5.6 6.6 6.4 12.0 7.1 2.7 35.6 177.2 19.1 6.6 15.5 15.8 115.9 30.6 5.4 3.0 34.2 7.5 8.3 6.9 10.6 EFCAB7 "KIAA1799, RP4-534K7.1" ENSG00000203965 "EF-hand calcium binding domain 7" A8K855 1 63523372-63572693 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 55.3;Excitatory neurons: 58.9;Inhibitory neurons: 47.7;Oligodendrocyte precursor cells: 41.7;Spermatocytes: 73.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029611, HPA029612, HPA029613" Enhanced Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli, Nucleoli rim" "Plasma membrane, Cytosol" "HPA029611: AB_10599972, HPA029612: AB_10600533, HPA029613: AB_10601004" "unprognostic (8.81e-2)" "unprognostic (5.24e-2)" "unprognostic (5.13e-2)" "unprognostic (1.64e-1)" "prognostic favorable (3.65e-4)" "unprognostic (1.70e-2)" "unprognostic (6.53e-4)" "unprognostic (2.99e-1)" "unprognostic (5.81e-3)" "unprognostic (1.69e-1)" "unprognostic (6.28e-2)" "unprognostic (1.66e-1)" "unprognostic (3.78e-2)" "unprognostic (2.18e-1)" "unprognostic (6.97e-2)" "unprognostic (9.90e-2)" "unprognostic (2.73e-1)" 2.7 5.3 7.3 2.2 7.6 2.0 6.0 8.9 10.3 5.8 10.1 3.4 2.0 6.1 6.2 2.9 8.1 4.6 6.5 7.4 9.3 5.6 1.7 4.0 3.6 6.8 7.2 8.0 2.9 10.4 5.9 3.2 7.0 5.4 3.0 8.9 3.1 5.0 6.7 3.1 2.1 4.7 6.5 2.7 3.2 14.6 8.2 7.3 5.9 3.9 3.3 3.7 2.8 8.3 6.5 5.7 7.1 4.5 7.5 11.0 3.6 4.1 4.6 7.2 8.8 1.7 5.0 4.4 9.6 2.5 14.5 6.0 6.1 4.1 8.5 8.6 4.3 3.6 10.4 3.9 4.6 5.1 3.2 6.1 9.9 8.6 5.6 11.4 6.1 8.2 4.8 7.3 4.7 1.5 9.9 3.5 3.1 4.6 5.6 6.2 10.7 4.6 11.1 3.6 15.2 5.8 8.1 4.5 10.5 9.6 4.5 3.8 1.7 4.1 3.5 12.1 4.0 4.7 8.7 5.0 7.4 3.5 6.0 10.1 0.4 0.1 1.2 0.3 1.6 1.8 1.4 1.4 0.8 1.9 1.4 1.3 0.0 1.3 2.6 1.0 1.6 0.6 7.3 7.6 8.9 10.3 7.4 9.3 6.8 7.2 7.0 6.5 8.2 8.3 3.1 12.8 4.1 23.2 6.0 3.1 5.6 7.0 5.7 7.7 2.6 3.9 7.8 2.8 5.6 5.5 4.2 3.7 2.1 0.6 7.9 3.8 55.3 19.9 8.0 3.2 1.8 1.3 58.9 0.7 2.0 5.6 3.6 3.4 2.5 7.9 2.2 1.2 2.6 0.0 47.7 1.3 8.2 2.5 1.6 8.8 10.8 1.8 1.8 14.0 1.9 5.2 2.1 41.7 21.9 1.4 0.3 13.5 6.0 1.4 0.5 5.5 27.5 11.3 26.3 11.8 5.3 73.4 22.7 3.8 2.3 1.2 3.4 5.8 2.1 1.6 EFHC2 "FLJ22843, MRX74" ENSG00000183690 "EF-hand domain containing 2" Q5JST6 X 44147872-44343672 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 17.1;fallopian tube: 14.7" "Cell type enhanced" "Detected in many" "Astrocytes: 32.0;Early spermatids: 78.6;Endometrial ciliated cells: 55.3;Respiratory ciliated cells: 79.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 16.4;NK-cell: 5.8" "Group enriched" "Detected in many" 7 "granulocytes: 16.4;NK-cells: 5.8" "Cell line enhanced" "Detected in some" "CAPAN-2: 3.7;HEL: 3.7;HMC-1: 12.0;NB-4: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034492 Approved Supported Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli fibrillar center" "Plasma membrane" "HPA034492: AB_10671227" "unprognostic (1.93e-1)" "unprognostic (7.80e-3)" "unprognostic (7.35e-2)" "unprognostic (2.75e-1)" "unprognostic (6.83e-3)" "unprognostic (5.07e-2)" "unprognostic (4.29e-2)" "unprognostic (1.75e-2)" "unprognostic (3.50e-2)" "unprognostic (2.90e-2)" "unprognostic (3.88e-2)" "unprognostic (1.86e-2)" "unprognostic (7.89e-2)" "unprognostic (1.06e-1)" "unprognostic (6.13e-4)" "unprognostic (1.64e-3)" "unprognostic (4.97e-2)" 0.4 0.3 1.5 0.3 1.9 1.4 0.7 1.0 1.4 2.7 17.1 1.1 0.3 3.7 3.4 1.8 14.7 1.4 3.7 1.5 2.1 1.8 0.0 2.0 0.2 5.2 3.9 1.7 0.1 0.2 3.1 0.8 2.8 1.9 0.3 2.0 8.2 3.6 0.0 3.5 0.5 1.6 2.7 0.3 0.9 6.7 2.5 0.5 2.3 0.1 0.4 0.5 0.9 2.6 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 3.7 0.0 0.0 0.0 1.1 0.0 0.3 0.0 0.1 0.0 0.1 3.7 0.0 0.0 0.0 0.0 12.0 0.2 0.2 0.1 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.0 0.0 1.9 0.4 0.0 0.0 0.3 0.0 0.0 1.0 0.0 0.2 0.4 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 16.4 0.0 0.0 1.5 0.0 0.6 0.1 0.6 0.1 0.3 0.1 0.5 0.7 1.5 5.8 0.0 0.0 0.0 0.9 1.5 1.9 1.0 1.4 1.5 2.1 5.2 3.9 2.8 2.7 2.5 2.6 0.1 0.0 3.9 32.0 0.0 3.1 6.0 9.6 1.2 0.2 0.4 0.5 10.8 4.3 5.1 0.0 2.1 0.0 1.6 1.2 1.9 0.9 78.6 55.3 6.0 0.3 0.0 1.7 7.2 5.9 0.1 0.8 0.0 17.1 16.4 3.8 0.4 0.0 0.3 0.0 1.7 1.5 4.1 0.0 0.4 19.0 6.8 4.9 0.0 0.0 0.4 5.3 3.1 1.5 0.2 1.0 0.0 7.2 0.2 1.0 3.8 0.7 79.6 0.1 6.6 0.1 3.7 11.3 10.5 7.3 2.8 0.3 1.6 0.4 5.2 6.0 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 121.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 358.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA022859: AB_1848029, HPA023092: AB_2293240, HPA023402: AB_1848031" "unprognostic (4.79e-2)" "unprognostic (6.54e-2)" "unprognostic (6.42e-2)" "unprognostic (4.37e-3)" "unprognostic (2.77e-1)" "unprognostic (3.44e-2)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-2)" "unprognostic (5.89e-3)" "unprognostic (5.22e-2)" "unprognostic (3.46e-1)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-3)" 21.7 20.8 22.7 20.8 28.6 14.5 20.0 36.4 35.7 28.3 13.2 21.2 23.2 23.4 38.0 27.5 24.2 21.8 33.9 29.5 9.3 29.8 44.5 27.8 25.3 52.7 13.6 19.3 18.6 33.6 12.0 20.4 59.0 26.9 18.4 121.6 17.3 29.3 41.6 21.2 23.5 36.1 7.0 23.5 22.8 22.1 16.1 24.3 37.8 49.1 27.9 26.9 14.0 23.9 55.3 49.0 15.0 12.4 59.9 68.8 29.9 38.6 54.0 31.5 41.3 10.8 40.4 33.8 35.5 87.6 41.8 17.9 23.9 52.9 38.3 78.3 13.1 33.7 22.7 22.0 57.5 13.0 34.1 58.6 29.6 31.2 49.0 52.2 40.2 16.4 18.7 44.3 56.5 36.1 36.5 11.9 8.5 47.3 30.4 14.5 29.4 16.1 38.0 34.1 10.0 34.6 76.9 10.8 30.6 39.3 34.4 22.0 56.3 55.6 50.9 27.4 40.9 31.3 28.8 20.9 41.2 31.0 29.0 12.0 16.8 17.4 16.2 23.3 14.5 12.6 13.0 13.3 17.3 11.2 11.6 12.0 10.1 15.5 40.9 4.0 11.3 15.8 22.7 28.6 36.4 35.7 29.5 9.3 52.7 13.6 59.0 7.0 16.1 23.9 32.6 41.7 42.8 90.8 40.7 21.2 25.3 29.5 25.0 358.8 29.9 16.6 57.4 28.6 37.5 51.5 91.8 22.8 34.1 33.5 21.5 28.7 4.5 25.9 35.1 29.1 11.4 13.3 126.8 30.9 22.2 34.4 29.0 20.7 25.9 19.8 25.0 79.9 44.5 26.9 122.6 18.7 26.4 59.4 25.0 8.0 19.9 52.9 8.8 60.0 53.3 42.3 42.2 77.9 55.6 25.5 36.0 44.4 32.6 55.8 39.9 58.4 27.7 107.5 19.7 32.3 41.4 52.9 30.9 39.1 31.4 37.1 37.3 36.8 17.0 36.7 EFR3B "FLJ37871, KIAA0953" ENSG00000084710 "EFR3 homolog B" Q9Y2G0 2 25042076-25159135 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.1;skeletal muscle: 20.0" "Cell type enhanced" "Detected in many" "Astrocytes: 127.0;Excitatory neurons: 58.5;Inhibitory neurons: 110.7;Late spermatids: 46.0;Microglial cells: 54.4;Oligodendrocytes: 51.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.3" "Cell line enhanced" "Detected in many" "AN3-CA: 10.3;BEWO: 12.0;SH-SY5Y: 10.7;SK-BR-3: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038089, HPA071831" Uncertain Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments, Cytosol" "HPA038089: AB_10672618, HPA071831: " "unprognostic (9.31e-2)" "unprognostic (3.92e-1)" "unprognostic (2.10e-1)" "unprognostic (2.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.44e-2)" "unprognostic (1.24e-3)" "unprognostic (3.82e-1)" "unprognostic (3.42e-1)" "unprognostic (1.32e-2)" "unprognostic (4.49e-6)" "unprognostic (4.83e-2)" "unprognostic (4.43e-2)" "unprognostic (1.89e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" 0.8 1.6 23.0 0.6 53.1 0.3 0.5 22.4 29.5 0.5 0.0 1.1 0.4 0.7 5.1 0.3 0.6 0.5 4.5 51.7 19.0 1.3 0.2 2.5 0.3 45.3 24.0 0.8 0.4 3.9 9.3 1.7 47.5 0.5 0.6 11.0 0.3 0.8 20.0 0.6 0.5 1.2 9.8 3.4 0.9 2.5 27.7 0.3 3.4 3.8 0.2 0.5 0.4 12.1 0.2 8.3 9.5 10.3 0.5 0.1 12.0 1.0 0.2 0.5 0.1 6.7 0.4 0.1 0.6 1.4 3.3 0.6 7.5 0.0 0.1 1.6 1.8 1.6 0.3 0.6 0.0 0.1 0.8 0.1 0.0 2.3 0.1 0.7 0.3 0.2 0.1 0.4 0.2 0.9 0.2 0.5 1.9 0.1 6.6 0.8 9.1 0.3 0.1 0.3 4.0 10.7 1.2 18.0 5.9 5.3 0.9 0.1 0.5 0.5 2.7 4.1 2.0 0.7 0.9 0.1 7.3 0.1 1.9 1.3 0.1 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.1 0.1 0.0 0.0 23.0 53.1 22.4 29.5 51.7 19.0 45.3 24.0 47.5 9.8 27.7 12.1 3.1 28.9 1.1 127.0 0.0 0.0 0.8 0.0 0.0 9.9 0.3 1.0 9.7 0.0 0.0 9.2 22.9 0.1 0.1 0.7 0.0 0.3 20.6 1.3 0.3 6.7 3.6 0.0 58.5 0.8 0.2 1.0 0.0 0.3 0.0 1.1 2.9 0.0 0.9 5.0 110.7 0.1 0.0 0.0 0.3 46.0 1.2 0.1 0.0 54.4 0.0 22.0 0.0 19.6 51.2 0.7 0.0 2.6 0.1 0.6 0.5 0.1 0.0 10.7 0.0 1.6 1.4 2.4 2.2 0.0 0.1 0.1 0.1 0.2 0.3 0.4 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 203.4;Early spermatids: 220.3;Excitatory neurons: 262.3;Inhibitory neurons: 245.4;Late spermatids: 495.6;Oligodendrocyte precursor cells: 226.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" 30.0 17.2 15.1 10.7 16.3 6.4 17.4 27.7 19.3 29.0 11.7 41.9 9.7 31.1 7.9 29.5 21.3 20.4 11.7 20.0 16.5 17.1 53.9 11.6 8.8 13.3 22.1 48.0 15.9 15.2 12.2 11.9 14.1 16.0 14.2 20.9 15.7 18.6 8.0 13.0 14.9 30.0 10.9 8.1 17.5 37.4 22.6 13.4 14.4 13.1 10.2 18.1 21.6 16.2 49.7 66.9 26.8 16.4 46.1 89.0 27.2 43.6 42.4 31.6 25.9 80.4 36.2 34.2 15.4 79.8 47.5 29.1 35.1 30.5 51.9 36.3 16.5 29.7 22.9 95.2 31.5 17.5 21.5 40.9 54.1 31.6 61.9 31.3 20.5 26.7 20.6 19.1 51.1 19.4 20.0 10.9 26.3 40.8 26.2 17.8 33.8 14.9 20.8 16.1 29.6 23.6 35.1 25.9 43.0 28.5 12.6 17.0 15.2 33.3 34.4 55.8 23.0 21.5 16.2 32.7 33.3 26.3 69.4 0.2 2.2 2.5 4.1 2.4 4.0 6.3 4.2 3.9 3.7 4.9 4.2 3.6 0.8 3.4 1.3 2.4 2.5 2.2 15.1 16.3 27.7 19.3 20.0 16.5 13.3 22.1 14.1 10.9 22.6 16.2 29.0 38.5 18.8 203.4 10.4 15.6 12.0 27.1 43.3 39.7 10.5 12.8 15.2 22.8 20.7 14.7 4.2 10.9 9.9 5.3 15.6 22.1 220.3 10.3 45.4 19.9 16.2 8.8 262.3 40.5 30.1 36.6 9.2 12.1 2.5 15.2 30.0 59.6 5.0 18.5 245.4 5.4 6.1 8.6 11.4 495.6 58.4 7.6 10.6 119.0 6.5 20.1 13.4 226.7 98.7 41.7 5.0 40.3 9.6 13.9 11.4 15.1 14.5 17.8 6.6 33.1 19.4 53.7 31.1 55.4 14.2 2.9 12.7 18.2 8.1 13.1 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 151.6;testis: 159.9" "Group enriched" "Detected in all" 10 "Early spermatids: 1033.0;Late spermatids: 1950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane" NA NA 10000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713, HPA067747: AB_2685896" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (6.35e-3)" "unprognostic (2.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.81e-5)" "unprognostic (1.46e-3)" "unprognostic (9.10e-3)" "unprognostic (9.44e-2)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (6.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.74e-1)" "unprognostic (2.59e-2)" 39.7 25.4 21.5 59.7 26.6 151.6 21.8 38.6 32.6 26.2 18.2 32.3 33.8 28.1 8.4 26.0 27.0 25.0 39.3 24.9 26.8 31.2 22.0 44.7 65.6 32.7 28.2 13.6 11.1 8.9 7.0 35.4 29.9 18.8 14.5 3.0 16.6 20.9 32.1 34.4 38.5 28.3 31.0 74.4 29.3 159.9 30.5 28.9 19.3 31.5 50.3 55.3 23.0 33.4 109.4 74.1 26.2 28.9 31.2 50.2 15.4 108.2 97.4 89.5 51.8 96.5 66.2 142.0 37.8 129.9 76.5 86.6 27.3 108.9 34.5 89.5 15.2 94.8 37.1 49.1 36.8 30.9 24.6 22.8 22.9 138.7 43.2 40.6 89.8 27.6 39.6 243.8 68.7 57.8 62.5 51.4 17.5 27.5 95.9 24.8 83.5 49.9 84.5 35.7 18.6 16.6 60.8 109.3 48.6 29.5 149.2 21.8 127.9 39.6 35.4 106.0 52.6 100.2 48.5 112.1 103.3 40.1 22.0 18.0 13.9 99.6 39.0 16.1 39.2 24.0 27.3 33.8 7.2 18.2 16.2 23.1 57.1 25.4 33.7 8.7 31.8 30.7 21.5 26.6 38.6 32.6 24.9 26.8 32.7 28.2 29.9 31.0 30.5 33.4 31.2 76.9 30.3 4.2 46.0 67.3 52.8 39.4 17.6 3.8 28.8 24.8 29.2 18.6 22.9 14.7 2.1 88.6 76.5 75.9 7.9 29.4 1033.0 41.9 24.4 29.3 6.6 19.8 1.7 40.8 24.5 32.4 25.5 54.9 93.8 37.2 10.4 10.9 32.2 5.0 3.5 27.7 12.2 37.4 61.0 1950.6 30.1 79.6 26.6 1.9 34.3 5.9 78.2 2.5 12.2 101.5 47.7 27.1 50.8 28.2 38.9 41.9 16.5 2.8 78.9 47.9 53.5 55.0 27.4 19.9 49.2 137.0 71.7 19.8 22.1 42.7 EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 161.9;Leydig cells: 99.1;Peritubular cells: 107.2;Sertoli cells: 236.7;Smooth muscle cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 312.2;BJ: 238.5;fHDF/TERT166: 258.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" 195.0 59.9 18.4 32.8 17.6 0.4 133.9 16.5 21.2 110.3 11.9 116.1 14.3 119.9 13.2 53.5 75.4 31.2 85.9 15.9 17.1 24.4 14.4 102.8 9.1 23.3 19.3 68.3 28.2 6.2 12.6 50.3 20.0 62.2 14.7 3.0 34.2 51.1 39.6 54.7 54.5 79.6 17.2 40.3 56.3 11.2 24.1 5.1 49.5 28.2 8.3 112.3 88.8 15.8 62.7 142.7 0.1 1.7 312.2 236.0 0.2 238.5 114.0 86.0 70.0 9.3 31.2 0.0 0.3 258.6 20.3 78.1 1.5 126.5 51.9 0.1 0.8 8.4 78.4 0.7 197.0 0.0 16.6 230.1 109.5 72.5 70.6 113.7 168.4 0.7 26.6 0.2 91.7 11.4 13.3 0.7 1.8 9.2 25.9 1.4 10.0 0.2 69.5 2.9 0.1 0.8 212.5 8.2 6.2 19.1 20.2 4.3 192.6 128.0 27.8 112.5 52.2 0.2 0.2 0.2 119.3 3.3 27.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 18.4 17.6 16.5 21.2 15.9 17.1 23.3 19.3 20.0 17.2 24.1 15.8 161.9 60.9 20.6 10.7 0.3 20.3 29.4 31.0 12.5 5.5 7.3 10.8 11.6 10.0 22.5 5.5 0.0 1.1 0.8 0.1 0.0 21.2 0.6 3.4 60.5 75.4 0.0 8.6 4.0 14.1 1.6 55.8 5.1 4.5 2.5 24.7 48.9 3.1 1.9 0.0 0.9 0.0 2.0 1.3 8.8 4.3 99.1 1.6 8.8 7.5 0.6 1.8 0.0 3.5 0.3 31.1 0.0 107.2 0.1 28.8 0.0 0.1 5.5 0.8 236.7 24.8 139.4 0.9 3.0 15.8 13.5 1.5 1.5 27.2 0.0 33.4 EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;esophagus: 43.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Hepatic stellate cells: 120.3;Syncytiotrophoblasts: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.8;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.8" "Cell line enhanced" "Detected in many" "BJ: 79.7;BJ hTERT+: 192.2;HEL: 77.4;U-266/70: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Approved "Plasma membrane" NA NA 15000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (3.44e-1)" "unprognostic (8.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (5.49e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.72e-2)" "unprognostic (9.92e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (4.88e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-3)" "unprognostic (4.92e-3)" 2.5 9.1 20.5 5.9 29.5 1.9 3.2 10.5 38.7 5.5 1.1 2.5 1.6 4.4 3.0 43.9 4.5 3.4 15.9 29.5 18.5 20.0 11.0 5.7 6.8 11.7 17.8 2.5 1.3 21.1 9.1 11.7 13.9 5.5 1.7 9.0 5.9 4.4 2.3 3.1 3.7 4.6 9.6 7.3 2.2 1.3 31.1 2.7 3.2 5.1 11.1 6.6 6.0 26.2 1.8 8.4 4.5 3.9 7.5 11.3 0.7 79.7 192.2 7.5 6.9 0.0 0.9 0.6 2.9 26.0 6.5 0.8 0.2 5.2 5.3 3.2 7.1 77.4 0.4 0.0 25.7 0.0 0.2 18.1 2.3 7.3 3.0 20.0 0.1 0.2 0.3 0.4 5.6 12.6 1.0 0.1 17.7 0.0 4.3 2.8 0.3 1.8 5.8 8.9 2.2 12.1 0.8 1.3 0.0 14.1 1.2 0.0 0.0 5.8 5.4 0.3 6.5 48.7 6.5 0.1 14.8 0.0 12.4 0.6 0.5 0.5 2.1 1.0 1.1 20.8 1.0 1.4 0.5 5.6 0.9 0.5 1.2 0.8 2.8 0.0 0.5 10.2 20.5 29.5 10.5 38.7 29.5 18.5 11.7 17.8 13.9 9.6 31.1 26.2 1.9 0.0 0.0 2.6 16.2 0.8 1.8 1.7 10.2 9.7 0.6 6.2 24.3 5.7 0.9 0.0 0.0 4.1 0.6 0.0 0.0 0.5 0.1 0.7 2.3 8.4 1.8 6.1 17.1 0.2 8.4 3.3 1.1 0.5 0.0 0.4 120.3 5.0 1.7 0.0 11.1 0.1 0.0 16.1 0.4 0.0 1.2 5.9 0.0 4.7 1.1 9.0 0.0 22.6 5.4 0.2 0.1 3.0 5.8 2.6 0.0 0.2 0.4 5.9 19.7 3.0 7.0 0.6 2.7 10.7 0.9 43.9 1.4 0.7 0.1 4.7 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 EIF2B2 "EIF-2Bbeta, EIF2B" ENSG00000119718 "Eukaryotic translation initiation factor 2B subunit beta" P49770 14 75002921-75012366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein biosynthesis" "Initiation factor" "Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 165.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005841, CAB037105, HPA048028" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 12000 "Cluster 44: Non-specific - Transcription" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB037105: AB_1840834, HPA005841: AB_1078725, HPA048028: AB_2680235" "unprognostic (1.10e-1)" "unprognostic (4.41e-2)" "unprognostic (5.70e-2)" "unprognostic (6.71e-2)" "unprognostic (7.64e-2)" "unprognostic (3.45e-3)" "prognostic unfavorable (2.26e-6)" "unprognostic (1.48e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-2)" "unprognostic (4.95e-2)" "unprognostic (1.01e-1)" "prognostic favorable (2.95e-4)" "unprognostic (4.15e-2)" "unprognostic (2.74e-1)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" 2.7 5.3 4.0 2.9 4.5 3.2 3.6 8.7 4.8 3.9 2.2 3.0 3.0 3.6 4.9 3.8 3.1 4.0 3.9 3.6 6.1 4.9 3.3 2.7 4.0 4.5 4.2 2.9 4.0 8.5 3.5 4.8 4.5 4.1 3.8 6.8 2.8 4.5 5.5 4.0 2.8 3.4 2.9 2.7 2.6 3.9 4.8 3.9 11.5 7.1 4.2 4.0 2.6 6.9 5.9 7.0 5.6 6.4 6.3 5.2 7.4 3.7 6.1 7.1 8.2 9.0 5.9 5.2 2.3 5.8 4.5 4.4 8.8 8.7 10.6 3.2 6.5 4.6 6.3 6.2 8.2 3.4 5.3 4.8 8.2 9.1 9.3 6.1 24.8 4.5 4.2 4.9 15.5 17.4 5.5 4.3 4.0 7.3 10.3 3.4 6.6 4.3 10.1 7.0 6.0 4.8 3.9 5.5 8.4 6.9 9.0 3.2 6.4 5.4 5.2 2.4 4.8 8.4 7.5 6.2 5.9 4.3 4.2 4.2 1.8 1.4 3.0 1.9 2.5 2.1 2.6 2.5 2.4 2.0 1.9 2.0 1.0 3.3 1.8 2.0 4.0 2.5 4.0 4.5 8.7 4.8 3.6 6.1 4.5 4.2 4.5 2.9 4.8 6.9 18.9 19.2 11.5 6.2 14.1 17.7 19.5 28.9 18.2 28.2 15.4 17.0 18.2 22.8 21.5 25.8 45.9 51.5 16.1 15.3 41.1 36.2 12.1 17.0 14.5 32.1 15.6 20.8 5.3 33.1 56.5 18.3 12.8 12.8 21.5 17.5 13.2 11.9 33.7 28.6 5.4 9.0 20.3 19.1 11.9 12.7 15.8 18.8 14.2 1.9 28.0 27.3 28.8 2.5 8.5 28.1 11.7 16.1 11.3 17.5 19.0 50.8 17.2 29.4 26.3 16.9 27.9 84.2 27.4 27.3 21.9 165.5 14.9 30.5 19.7 19.2 EIF5A "EIF-5A, EIF5A1, MGC104255, MGC99547" ENSG00000132507 "Eukaryotic translation initiation factor 5A" P63241 17 7306999-7312463 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005042, HPA061298, HPA074052" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Plasma membrane" "CAB005042: AB_562281, HPA061298: AB_2684472, HPA074052: " "unprognostic (3.72e-1)" "unprognostic (1.67e-1)" "unprognostic (8.10e-2)" "unprognostic (2.80e-1)" "unprognostic (6.95e-2)" "unprognostic (1.39e-2)" "unprognostic (1.06e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (4.10e-1)" "unprognostic (4.11e-2)" "unprognostic (1.64e-2)" "unprognostic (8.25e-2)" "prognostic unfavorable (1.63e-5)" "unprognostic (3.53e-1)" "unprognostic (2.79e-1)" "unprognostic (6.01e-2)" "unprognostic (7.65e-2)" 317.2 309.3 82.3 138.3 83.8 221.5 240.7 85.5 99.0 222.7 77.8 247.5 113.0 206.2 85.8 575.9 188.1 73.7 316.1 87.8 89.8 241.7 495.6 244.5 135.0 87.7 86.4 161.2 295.0 79.7 166.7 96.4 93.0 189.1 125.7 47.6 230.9 65.6 572.1 407.8 207.5 106.1 86.5 227.4 226.7 201.7 92.3 122.5 181.6 160.3 154.4 221.3 281.8 88.6 838.2 958.6 275.8 570.6 220.8 270.2 427.1 546.2 360.7 730.1 501.6 583.6 343.3 749.7 350.9 451.4 300.3 572.3 610.0 777.8 665.9 466.2 987.2 477.9 710.1 750.6 388.6 324.0 431.7 302.5 374.9 587.8 736.0 259.1 501.4 232.0 673.8 192.2 527.3 496.2 388.6 523.3 525.8 477.2 498.0 412.0 320.5 732.4 464.6 393.8 340.5 431.8 330.0 469.4 360.8 212.3 327.2 258.4 427.7 567.6 379.5 326.2 896.4 168.8 229.9 443.6 515.1 527.2 642.2 146.8 137.6 102.0 157.4 193.1 187.5 154.5 153.1 137.2 215.9 149.1 139.6 144.6 62.0 195.1 186.5 225.0 156.7 200.3 82.3 83.8 85.5 99.0 87.8 89.8 87.7 86.4 93.0 86.5 92.3 88.6 180.1 54.5 37.9 6.2 241.9 349.0 67.9 226.5 378.5 88.3 258.8 138.7 77.8 125.8 72.7 62.5 14.6 324.3 200.3 316.0 74.3 317.3 153.8 136.4 255.2 176.6 150.6 456.1 6.8 239.8 633.8 199.6 172.8 187.8 138.4 87.3 105.7 236.4 296.8 50.5 7.0 317.4 83.4 133.6 283.1 112.9 100.6 151.9 263.3 4.7 245.0 122.2 216.3 2.0 11.5 322.0 223.7 81.3 386.7 507.1 229.3 127.1 41.3 65.0 92.1 160.7 262.1 200.4 82.6 572.0 313.7 428.4 179.3 290.7 384.7 207.0 EIF5AL1 "bA342M3.3, EIF5AP1" ENSG00000253626 "Eukaryotic translation initiation factor 5A like 1" Q6IS14 10 79512533-79516440 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.2;Intestinal goblet cells: 96.7;Spermatocytes: 76.5;Undifferentiated cells: 121.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "U-251 MG: 2.2" HPA074052 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Plasma membrane" "HPA074052: " "unprognostic (2.16e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.55e-1)" "unprognostic (4.14e-3)" "unprognostic (1.50e-1)" "unprognostic (3.48e-2)" "unprognostic (4.25e-2)" "unprognostic (2.50e-3)" "unprognostic (2.04e-2)" "unprognostic (3.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.79e-3)" "unprognostic (1.56e-1)" "unprognostic (8.63e-2)" "unprognostic (1.87e-1)" "unprognostic (6.68e-2)" "unprognostic (1.81e-1)" 0.8 0.8 0.1 0.2 0.1 0.2 0.6 0.5 0.3 0.4 0.0 0.6 0.2 0.5 0.2 1.4 0.4 0.0 0.9 0.1 0.0 0.5 1.3 0.6 0.3 0.0 0.0 0.3 0.7 0.2 0.4 0.0 0.0 0.5 0.2 0.8 0.5 0.0 1.5 1.0 0.5 0.0 0.0 0.5 0.5 10.6 0.0 0.0 0.5 0.0 0.3 0.5 0.7 0.1 0.4 0.8 0.3 1.7 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.6 0.3 0.9 0.3 0.0 0.2 0.5 0.1 0.0 0.2 0.2 0.7 0.2 1.0 0.4 0.1 0.3 0.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.3 0.1 0.6 1.0 0.9 1.2 0.1 0.1 0.3 0.7 0.6 0.5 0.8 0.2 0.5 0.5 0.4 0.6 0.1 0.8 0.7 0.2 0.4 1.0 1.1 2.2 0.4 0.5 0.8 0.7 0.2 0.6 1.1 0.8 0.6 1.2 2.0 1.4 1.3 1.2 1.3 1.6 1.3 0.9 1.3 0.7 1.7 1.3 2.5 1.0 0.8 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 16.0 30.0 1.3 10.4 33.8 3.0 7.8 0.0 0.6 5.1 2.4 43.1 2.8 16.1 0.0 0.0 20.8 2.4 79.2 11.7 64.5 14.7 2.9 4.4 12.9 60.0 10.7 0.6 47.8 35.1 15.5 0.0 3.2 48.2 0.9 4.2 5.1 17.5 1.7 0.6 96.7 8.2 8.7 27.9 8.7 5.0 7.2 19.6 0.0 41.9 1.2 13.4 0.0 1.0 65.6 61.2 3.0 0.5 10.3 66.5 11.1 6.1 0.5 0.0 6.9 25.9 76.5 4.3 0.0 34.5 27.6 8.9 3.3 121.3 5.0 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELFN1 PPP1R28 ENSG00000225968 "Extracellular leucine rich repeat and fibronectin type III domain containing 1" P0C7U0 7 1688119-1747954 "Predicted membrane proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2;liver: 14.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Endothelial cells: 5.7;Hepatic stellate cells: 7.1;Hepatocytes: 13.5;Inhibitory neurons: 19.2;Rod photoreceptor cells: 7.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 31.2;U-138 MG: 18.5;U-2 OS: 27.0;U-2197: 32.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA066382 Approved "Nucleoplasm,Cell Junctions" NA NA 43000 "Cluster 15: Liver - Metabolism" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "HPA066382: AB_2732744" "unprognostic (8.45e-2)" "unprognostic (3.39e-3)" "unprognostic (6.54e-4)" "unprognostic (1.64e-1)" "unprognostic (1.30e-1)" "unprognostic (1.44e-1)" "prognostic favorable (9.68e-4)" "unprognostic (4.60e-3)" "unprognostic (1.63e-3)" "unprognostic (6.60e-2)" "unprognostic (4.14e-3)" "unprognostic (1.11e-2)" "unprognostic (2.31e-2)" "unprognostic (7.47e-3)" "unprognostic (8.63e-2)" "unprognostic (2.78e-1)" "unprognostic (4.07e-1)" 3.1 0.4 1.5 0.3 2.5 0.0 1.5 1.0 3.4 4.2 0.0 0.6 0.1 2.9 0.1 0.5 1.5 0.4 4.6 1.0 4.4 3.9 14.5 0.6 0.1 3.2 4.6 0.4 0.6 0.1 0.8 0.4 3.2 1.0 0.0 3.0 0.4 0.1 0.7 1.0 0.8 0.2 7.2 1.1 0.6 0.8 2.6 0.7 0.8 0.4 0.0 0.6 1.7 0.8 0.3 0.0 4.6 9.7 0.0 1.4 0.0 1.6 0.0 0.0 0.0 0.1 0.5 0.0 4.6 2.1 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 0.8 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 5.7 0.0 4.7 1.9 0.0 1.1 31.2 0.0 3.1 0.0 0.0 4.3 2.0 0.3 0.2 0.0 0.5 0.1 0.3 0.1 18.5 27.0 32.1 0.0 0.0 0.4 8.3 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 2.5 1.0 3.4 1.0 4.4 3.2 4.6 3.2 7.2 2.6 0.8 4.8 0.0 0.6 0.0 0.0 0.1 0.3 0.3 2.8 1.3 0.1 0.3 1.8 0.0 0.0 0.0 6.2 0.0 0.0 0.0 3.9 0.1 0.1 0.3 2.0 5.7 0.0 0.0 0.8 0.0 0.0 1.3 0.0 0.1 0.0 0.0 7.1 13.5 0.1 0.0 19.2 0.0 0.0 0.6 0.7 0.1 0.9 0.1 1.8 1.0 0.0 0.9 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 7.8 0.0 0.0 0.9 0.0 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ELOC "SIII, TCEB1" ENSG00000154582 "Elongin C" Q15369 8 73939169-73972287 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Transcription, Transcription regulation, Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 266.1;Extravillous trophoblasts: 326.2;Hofbauer cells: 313.7;Pancreatic endocrine cells: 317.3;Proximal tubular cells: 341.3;Syncytiotrophoblasts: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078113 Approved "Nucleoli,Vesicles,Cell Junctions" NA NA 140000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 7: Non-specific - Mitochondria" Vesicles "Nucleoli, Cell Junctions" "HPA078113: AB_2686877" "prognostic unfavorable (6.48e-4)" "unprognostic (1.60e-1)" "unprognostic (3.14e-1)" "unprognostic (2.83e-2)" "unprognostic (2.46e-2)" "unprognostic (8.02e-3)" "unprognostic (5.84e-3)" "unprognostic (2.19e-2)" "unprognostic (1.77e-1)" "unprognostic (6.99e-3)" "unprognostic (4.02e-3)" "unprognostic (3.33e-2)" "unprognostic (2.77e-3)" "unprognostic (3.84e-2)" "unprognostic (5.33e-2)" "unprognostic (1.67e-1)" "unprognostic (8.95e-2)" 78.3 83.9 86.5 45.0 89.6 93.1 59.9 88.6 116.1 47.9 79.8 61.3 30.2 48.1 67.0 75.3 46.2 39.3 141.0 92.5 85.3 97.2 76.0 62.0 52.5 83.6 83.9 46.1 41.1 58.5 57.2 56.0 83.9 45.2 44.8 69.4 46.7 43.7 190.3 48.4 40.7 54.8 84.2 48.2 57.3 111.2 85.1 64.4 43.3 125.6 65.7 69.3 52.0 89.5 211.2 169.2 151.1 110.2 113.0 146.7 108.1 203.6 165.3 194.8 199.0 151.1 178.2 106.3 160.7 181.9 263.4 147.2 168.7 203.6 256.8 123.2 141.5 185.7 174.2 243.0 147.3 120.4 133.6 149.4 159.9 177.0 226.8 144.2 184.8 180.2 166.2 137.8 260.2 155.9 311.7 214.9 137.5 341.9 271.8 111.9 95.1 100.8 216.2 181.9 142.1 134.3 85.2 458.9 202.4 155.1 169.2 127.9 142.2 140.1 160.6 156.1 208.1 155.6 204.5 198.9 169.6 130.2 175.0 138.6 66.4 85.6 62.0 78.6 68.3 83.1 74.2 70.8 73.6 73.9 66.5 67.5 79.8 73.4 77.3 118.4 99.1 60.0 86.5 89.6 88.6 116.1 92.5 85.3 83.6 83.9 83.9 84.2 85.1 89.5 236.0 67.3 98.9 0.0 24.8 0.0 0.0 0.0 0.0 0.0 147.6 185.4 0.0 0.0 49.5 119.5 0.0 220.1 74.5 0.0 266.1 216.7 0.0 147.9 98.9 77.1 0.0 0.0 0.0 227.2 326.2 66.0 0.0 168.8 69.4 65.9 0.0 0.0 313.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 80.9 0.0 0.0 112.7 0.0 0.0 0.0 0.0 317.3 0.0 0.0 12.1 0.0 0.0 341.3 63.4 0.0 0.0 0.0 78.2 0.0 0.0 0.0 0.0 332.5 40.7 98.8 0.0 0.0 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENAH "FLJ10773, MENA, NDPP1" ENSG00000154380 "ENAH actin regulator" Q8N8S7 1 225486835-225653142 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028448, HPA028696" Enhanced Enhanced "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 15000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028448: AB_10600766, HPA028696: AB_10611249" "unprognostic (2.56e-2)" "unprognostic (8.03e-2)" "unprognostic (1.09e-1)" "unprognostic (4.35e-2)" "unprognostic (5.61e-3)" "unprognostic (2.85e-1)" "unprognostic (1.21e-3)" "unprognostic (2.30e-1)" "unprognostic (2.23e-1)" "unprognostic (9.22e-2)" "unprognostic (4.71e-3)" "unprognostic (2.14e-1)" "unprognostic (2.24e-3)" "unprognostic (8.84e-2)" "unprognostic (5.83e-2)" "unprognostic (7.92e-2)" "unprognostic (2.93e-2)" 26.3 20.2 30.3 16.5 25.9 0.5 13.4 21.1 20.3 13.5 2.0 30.9 12.5 23.6 13.7 16.2 15.0 23.6 25.2 27.2 35.7 7.0 7.5 17.3 4.7 35.5 34.2 22.6 22.3 17.9 6.5 18.2 28.1 21.4 10.1 8.1 20.9 30.6 20.4 10.6 10.8 57.6 22.4 24.8 23.3 25.0 40.9 9.0 7.3 11.5 4.6 30.1 13.8 28.7 91.6 71.9 87.1 79.0 33.3 43.7 111.9 99.1 47.3 58.4 43.9 46.4 33.0 38.7 256.8 153.9 52.5 79.0 102.7 37.4 55.2 0.6 63.4 40.3 62.4 63.1 99.4 4.8 1.5 67.9 44.2 75.9 96.2 47.8 47.0 10.7 2.7 1.9 58.6 17.7 18.5 4.7 146.8 23.9 64.3 27.6 122.9 1.1 26.9 69.5 85.3 68.9 194.6 73.3 63.3 66.1 87.5 5.9 92.2 150.4 109.8 126.8 198.6 4.2 11.4 25.7 82.7 5.0 78.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 30.3 25.9 21.1 20.3 27.2 35.7 35.5 34.2 28.1 22.4 40.9 28.7 117.0 12.8 37.3 81.9 3.8 129.0 172.5 64.4 26.2 11.2 96.2 57.9 119.3 54.3 56.5 22.0 62.6 65.0 1.7 14.8 3.9 84.7 74.8 127.2 60.5 79.3 41.4 0.0 86.3 100.5 18.5 71.6 63.2 75.0 5.1 194.2 23.9 12.9 11.2 16.8 155.0 27.3 26.4 1.6 29.7 24.3 58.1 4.3 83.6 41.2 3.8 32.6 3.1 160.4 151.3 61.5 16.5 168.9 1.6 133.1 3.5 19.6 137.8 19.0 92.1 69.4 166.1 13.4 37.2 25.6 134.1 60.5 4.8 220.7 31.3 100.3 ENC1 "ENC-1, KLHL37, NRPB, PIG10, TP53I10" ENSG00000171617 "Ectodermal-neural cortex 1" O14682 5 74627406-74641424 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 197.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 271.6;Theca cells: 210.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 51 "amygdala: 61.3;basal ganglia: 114.2;cerebral cortex: 190.0;hippocampal formation: 197.3;white matter: 68.6" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 263.2" HPA078061 Uncertain "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA078061: " "prognostic unfavorable (3.88e-4)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-3)" "unprognostic (1.36e-1)" "unprognostic (9.74e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (4.98e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (9.69e-2)" "unprognostic (3.08e-1)" "unprognostic (2.88e-1)" "unprognostic (5.65e-2)" 5.5 2.0 61.3 13.5 114.2 18.0 4.3 0.0 190.0 9.9 0.0 14.7 17.9 6.9 3.8 5.7 2.4 19.2 8.2 197.3 0.0 5.7 18.8 12.7 5.8 0.0 0.0 15.0 32.8 24.7 6.8 11.4 2.4 11.8 21.2 2.3 15.6 19.3 4.7 4.3 21.6 7.6 1.0 11.4 27.0 12.0 0.0 7.1 2.7 3.8 5.0 20.3 3.1 68.6 40.0 47.9 45.8 22.1 20.1 4.5 109.6 27.7 27.6 27.8 19.9 74.0 60.0 0.0 30.9 21.5 46.0 29.9 0.7 46.7 60.0 0.8 3.4 43.6 9.5 36.8 1.9 4.9 0.4 7.6 3.3 72.3 7.3 102.2 23.2 9.5 9.9 23.4 81.5 10.4 4.2 6.4 51.2 39.1 40.4 4.8 31.0 4.0 17.3 27.5 60.3 26.9 4.5 20.5 2.4 58.3 9.7 6.6 59.2 46.3 75.3 30.4 87.7 0.5 0.1 0.8 53.8 4.0 73.9 0.0 2.7 2.6 1.2 2.3 0.0 0.0 0.2 1.4 1.2 0.1 0.1 1.3 0.6 1.4 0.6 0.0 0.0 0.8 61.3 114.2 0.0 190.0 197.3 0.0 0.0 0.0 2.4 1.0 0.0 68.6 10.6 0.0 17.0 18.9 11.7 2.5 14.0 20.2 1.2 1.1 9.1 14.7 2.3 17.2 22.6 11.0 2.1 14.6 51.9 15.3 3.9 69.6 16.2 12.8 7.0 13.9 15.5 0.4 271.6 31.7 5.7 40.4 31.6 11.0 21.5 26.4 41.4 18.0 26.5 0.0 25.4 20.9 57.0 8.2 4.9 20.4 37.6 10.2 0.0 25.3 6.2 0.6 0.0 20.6 15.7 67.0 10.1 33.4 23.2 17.6 12.3 4.4 12.9 1.2 6.6 4.4 41.9 0.5 1.0 3.2 1.1 2.6 15.9 210.4 33.4 18.3 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 ENKD1 "C16orf48, DKFZP434A1319, FBB11" ENSG00000124074 "Enkurin domain containing 1" Q9H0I2 16 67662945-67667265 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 34.2;Endometrial ciliated cells: 38.3;Respiratory ciliated cells: 42.5;Spermatocytes: 37.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041163, HPA041478" Approved Approved "Plasma membrane,Centrosome,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Centrosome" Cytosol "HPA041163: AB_10794986, HPA041478: AB_10794668" "unprognostic (6.02e-2)" "unprognostic (1.81e-1)" "unprognostic (1.59e-3)" "prognostic favorable (1.68e-4)" "unprognostic (4.41e-1)" "unprognostic (1.06e-1)" "unprognostic (3.78e-3)" "unprognostic (1.10e-1)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (5.69e-2)" "unprognostic (6.58e-2)" "unprognostic (1.67e-1)" "unprognostic (2.44e-1)" "unprognostic (3.31e-2)" "unprognostic (2.23e-1)" "unprognostic (9.60e-2)" 12.8 12.8 8.4 4.6 8.3 3.5 14.9 22.0 11.5 23.2 13.6 28.6 3.9 21.2 5.6 8.6 30.7 3.6 13.2 8.2 8.6 26.6 11.6 14.7 2.2 9.9 10.9 21.2 67.2 16.0 25.6 3.3 8.4 20.6 2.7 8.5 13.7 9.2 9.5 12.1 11.1 4.4 10.0 11.9 15.9 41.1 9.1 4.7 22.3 1.6 2.5 21.5 14.2 8.5 11.1 7.5 17.2 8.0 5.6 5.8 8.5 8.5 5.1 6.7 8.1 5.5 16.5 4.1 14.3 5.3 0.0 12.7 4.5 10.2 8.2 6.5 10.2 4.1 25.7 13.1 9.1 7.4 5.4 5.1 7.3 9.1 8.2 15.4 5.5 13.3 6.9 2.5 3.5 5.7 8.2 30.9 8.2 11.5 3.0 28.5 1.8 31.3 7.2 1.1 17.4 18.9 18.2 1.8 9.7 3.9 15.8 10.5 14.3 8.1 11.4 15.2 0.1 19.1 9.2 4.5 12.3 10.8 2.5 0.0 0.4 0.0 0.1 0.1 0.4 0.2 0.3 0.2 0.1 0.0 0.2 0.3 0.9 0.2 0.2 1.3 0.0 0.1 8.4 8.3 22.0 11.5 8.2 8.6 9.9 10.9 8.4 10.0 9.1 8.5 8.8 22.4 14.4 8.8 1.7 6.9 5.9 6.2 4.0 3.6 10.4 11.2 5.5 10.0 4.0 9.2 4.2 3.1 1.5 4.4 1.9 13.1 34.2 38.3 10.5 8.6 13.2 2.1 2.1 10.7 2.4 7.5 1.5 9.5 1.3 7.4 10.4 26.4 4.7 3.3 2.2 6.0 2.0 3.2 4.3 20.6 13.1 2.6 5.4 0.0 3.0 8.8 0.0 2.5 1.7 9.5 1.4 14.3 2.6 6.0 1.8 7.3 42.5 10.5 6.6 9.1 8.0 37.0 7.9 1.2 5.3 3.4 1.9 11.6 4.9 4.4 ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879190 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 2259.3;Extravillous trophoblasts: 2078.5;Muller glia cells: 2624.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394, CAB080034" Supported Enhanced "Plasma membrane,Cytosol" NA NA 310000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB018614: AB_2099061, CAB069394: , CAB080034: , HPA068284: , HPA068721: AB_2732119" "unprognostic (6.51e-3)" "unprognostic (9.50e-3)" "unprognostic (3.56e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.71e-4)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (2.37e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (1.67e-2)" "unprognostic (1.46e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.36e-3)" 463.4 418.4 552.9 553.3 591.7 792.8 409.1 679.7 749.9 370.7 585.6 382.6 401.2 321.7 125.7 1049.4 281.6 302.0 328.2 638.1 599.6 1063.6 612.2 453.2 492.4 624.1 607.7 295.0 220.8 347.2 245.7 362.7 602.9 279.2 358.3 741.5 581.3 354.2 231.0 548.1 382.3 471.3 583.4 394.9 321.6 217.7 585.3 455.6 271.4 146.5 695.4 485.9 519.7 571.5 3637.0 3088.4 1461.8 1258.6 1194.2 1323.8 1316.6 1919.1 2110.9 4044.1 3767.4 1986.9 2041.5 2586.5 2496.8 2328.5 1651.8 1736.8 2511.5 5127.7 4081.0 1780.5 2645.9 2191.3 2848.0 2511.0 1789.6 4421.6 1290.1 1377.4 1526.1 3208.9 4825.9 3045.2 2630.1 1294.6 2444.4 982.3 2664.2 1784.1 1685.2 2354.5 1600.3 1290.4 3063.4 1712.4 2172.9 4259.0 4815.0 843.6 1961.4 1211.1 2251.0 3232.5 2407.8 1748.4 1621.8 1302.1 2424.7 2774.5 2444.5 2402.3 3328.3 2771.0 2120.4 3906.9 4313.8 3556.1 2388.6 195.9 1198.7 232.3 528.4 822.7 597.3 411.2 552.5 543.2 1216.4 386.1 443.4 466.0 230.6 635.3 830.6 336.1 700.0 2171.2 552.9 591.7 679.7 749.9 638.1 599.6 624.1 607.7 602.9 583.4 585.3 571.5 140.0 278.9 499.1 99.6 222.3 416.5 570.9 1939.8 348.8 178.2 242.7 324.6 69.6 283.1 657.4 606.9 70.9 1045.4 194.0 455.9 925.4 2259.3 281.3 205.3 227.7 314.3 189.0 145.4 32.0 1399.1 2078.5 303.5 144.8 248.4 297.2 408.6 133.5 351.7 1147.4 482.9 33.2 297.3 787.3 356.4 524.5 699.6 171.5 454.2 448.2 30.9 1558.2 2624.9 279.1 28.6 26.9 1433.6 366.9 135.1 211.0 555.7 742.2 1005.4 245.7 216.6 151.2 156.1 402.5 215.1 154.3 468.1 349.6 1001.8 285.6 609.8 528.4 444.2 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 1695.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.2;Cone photoreceptor cells: 312.8;Horizontal cells: 429.0;Rod photoreceptor cells: 787.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.3;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.4;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 537.4;U-87 MG: 398.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 55000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 25.6 46.7 280.8 20.0 289.7 9.6 20.2 291.2 400.7 55.9 97.5 74.0 10.2 40.1 12.6 15.3 40.2 17.9 53.7 295.0 289.4 27.8 7.7 33.8 26.3 289.4 189.9 29.7 9.0 43.6 124.4 10.4 282.2 34.9 15.5 1695.6 13.8 34.4 7.4 19.3 37.1 35.0 164.3 26.4 30.4 9.6 259.0 26.7 42.0 6.4 24.4 57.4 44.1 306.2 74.3 45.3 16.2 0.5 23.7 26.0 1.5 56.5 37.3 82.0 125.9 8.6 5.8 103.9 9.5 24.3 108.8 11.0 173.0 15.4 116.1 211.9 16.6 141.0 47.7 60.3 17.4 8.3 161.2 13.0 0.7 61.1 11.5 537.4 17.5 137.9 9.5 1.1 56.3 10.3 66.9 8.8 84.9 31.7 27.2 75.0 13.9 22.9 38.5 9.8 128.3 94.0 14.3 1.0 96.3 76.4 4.5 3.9 20.9 69.4 73.7 95.7 73.0 73.3 79.5 15.4 398.4 0.3 15.2 2.1 0.0 0.2 9.9 0.0 11.3 6.8 13.1 11.4 0.1 4.4 8.2 8.6 7.0 0.4 0.3 1.2 7.5 6.1 280.8 289.7 291.2 400.7 295.0 289.4 289.4 189.9 282.2 164.3 259.0 306.2 3.2 35.3 27.4 54.2 11.2 6.2 2.3 45.2 1.8 318.2 5.2 4.3 16.1 1.5 17.2 12.9 312.8 0.3 7.5 0.3 0.0 17.0 0.5 9.6 2.1 9.9 23.9 7.0 96.2 1.8 1.1 8.3 2.0 2.7 67.2 1.0 5.3 0.2 1.7 429.0 89.4 0.5 18.3 0.6 6.9 0.3 5.6 5.9 12.4 25.3 3.5 146.1 0.0 23.6 31.5 9.3 1.2 9.8 9.2 2.5 0.1 0.2 32.2 787.2 13.1 8.1 20.2 1.5 2.5 1.1 2.3 0.3 17.1 0.3 0.4 2.2 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 26 "skeletal muscle: 14758.3;tongue: 10771.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 582.2;Skeletal myocytes: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 263.8;HeLa: 120.0;HMC-1: 115.1;RH-30: 170.2;RPMI-8226: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" Yes No 86000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: AB_2732119" "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.8 5.5 3.8 15.6 3.9 20.4 8.0 7.1 4.3 6.6 5.0 8.0 20.1 7.2 7.1 173.8 7.4 2.6 499.8 3.5 3.7 10.3 108.0 8.6 13.0 4.3 5.0 6.0 5.5 4.0 7.9 6.3 4.6 47.3 3.0 5.0 116.8 3.1 14758.3 8.3 15.6 2.8 4.1 16.9 10.1 9.3 4.3 5.8 10.3 10771.0 4.9 5.6 5.0 4.9 12.0 25.5 11.3 10.7 9.1 2.2 27.6 21.0 2.7 1.5 1.3 12.8 8.1 21.9 25.8 1.9 3.5 15.4 3.8 1.9 1.0 263.8 24.3 21.9 120.0 18.9 3.7 6.8 115.1 14.4 3.8 2.1 4.1 9.8 1.4 24.8 10.2 39.0 4.9 6.6 7.9 26.5 14.8 3.3 10.6 34.6 170.2 96.9 3.1 7.9 7.1 27.1 13.6 11.4 14.7 7.6 10.2 7.0 6.5 12.1 21.3 5.4 16.0 27.6 16.8 18.2 6.7 20.8 12.2 31.4 28.5 50.4 36.8 41.5 24.8 24.5 30.8 34.4 37.6 20.1 20.0 32.2 34.4 34.9 47.6 29.9 43.2 83.6 3.8 3.9 7.1 4.3 3.5 3.7 4.3 5.0 4.6 4.1 4.3 4.9 1.2 0.0 1.8 2.3 2.7 2.0 1.2 2.1 4.0 6.6 3.0 3.0 582.2 0.0 2.2 5.5 4.2 5.4 3.2 2.9 0.0 1.5 1.8 0.9 1.6 7.3 0.0 3.8 0.2 0.8 3.8 17.3 4.6 2.2 8.2 2.4 2.2 56.2 4.5 3.3 0.2 2.2 2.0 3.5 6.7 3.7 0.3 4.3 1.8 0.0 78.3 1.9 4.1 1.0 0.5 1.8 1.9 0.4 2.3 1.2 6.6 9.5 0.3 2.5 6.6 248.4 55.8 7.9 7.5 2.1 1.8 3.3 4.5 1.1 2.6 0.8 ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213518-43786908 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Astrocytes: 173.3;Early spermatids: 190.8;Excitatory neurons: 452.3;Inhibitory neurons: 692.0;Late spermatids: 264.8;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 771.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 17.3;RH-30: 24.1;TIME: 17.8;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" 3.4 1.0 7.8 2.5 12.5 0.3 1.8 4.6 9.2 3.3 0.4 8.5 0.6 5.0 0.9 1.0 2.7 1.6 4.7 7.7 7.9 3.5 0.4 0.9 2.2 10.0 6.9 6.4 1.3 0.7 1.9 4.4 10.3 3.0 1.5 2.0 0.4 3.7 8.1 0.5 1.4 4.2 7.4 0.7 2.3 9.0 8.9 2.8 0.4 0.7 1.4 3.1 2.1 14.1 0.2 0.3 3.4 0.0 3.4 13.2 0.7 1.6 3.8 5.7 5.4 2.4 0.4 0.0 0.2 5.1 0.6 0.1 0.7 0.4 2.5 4.2 5.6 0.7 4.0 0.1 2.1 0.1 0.9 12.7 1.2 17.3 8.7 0.9 0.4 2.8 0.0 0.8 3.5 0.3 5.9 0.2 3.8 0.1 1.5 0.0 24.1 0.0 3.0 0.7 11.8 4.5 2.1 3.5 0.9 2.6 0.7 0.1 17.8 1.9 0.6 17.9 1.9 0.0 0.1 0.1 8.3 0.0 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 12.5 4.6 9.2 7.7 7.9 10.0 6.9 10.3 7.4 8.9 14.1 1.5 3.2 0.0 173.3 0.0 0.6 1.3 0.0 2.2 4.3 1.2 0.6 3.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 5.9 0.6 190.8 0.1 1.9 0.4 0.0 0.0 452.3 0.4 0.0 2.5 0.0 0.1 0.0 2.3 0.0 0.0 0.2 1.7 692.0 0.0 0.0 0.0 1.8 264.8 12.2 0.4 0.0 15.0 0.0 0.3 0.0 167.9 771.1 0.1 0.0 4.5 0.0 2.7 0.0 1.1 5.3 0.4 6.6 6.1 5.1 3.8 7.3 0.3 0.3 0.3 0.1 12.3 0.0 0.5 ENOX2 "APK1, COVA1, tNOX" ENSG00000165675 "Ecto-NOX disulfide-thiol exchanger 2" Q16206 X 130622325-130903317 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Growth regulation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 51.3;Oligodendrocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000514, HPA003027" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA000514: AB_1078558, HPA003027: " "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.75e-2)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (6.27e-3)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (4.60e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" 6.4 7.6 6.4 5.6 9.2 3.3 6.4 5.5 6.9 6.9 5.0 4.9 4.1 8.8 5.4 7.2 7.6 6.6 10.8 6.1 8.0 4.3 5.4 5.1 8.2 7.5 6.7 7.9 3.8 7.8 1.7 5.9 6.4 6.1 5.3 2.8 4.6 8.0 6.7 4.4 4.7 8.2 6.2 7.3 5.6 5.9 7.6 8.6 6.3 8.3 9.5 6.9 3.0 9.2 15.7 12.9 16.2 7.4 15.3 13.2 7.3 12.6 15.3 8.5 5.3 6.0 12.9 11.3 30.1 11.6 11.4 10.9 11.4 13.0 10.7 15.3 12.1 24.6 7.4 6.6 10.6 20.2 16.6 10.7 19.3 10.1 11.3 4.0 12.8 9.9 17.1 8.6 7.0 21.4 13.2 3.7 9.0 20.8 16.0 8.7 10.4 12.9 10.0 10.5 5.5 9.6 12.2 7.2 17.0 6.1 4.6 10.1 10.5 8.3 4.9 13.2 26.4 9.2 4.9 7.6 23.6 19.2 13.8 7.0 11.1 12.9 9.4 14.1 9.6 11.7 10.5 9.7 10.8 11.9 11.2 9.7 1.8 10.8 7.7 5.8 12.4 9.3 6.4 9.2 5.5 6.9 6.1 8.0 7.5 6.7 6.4 6.2 7.6 9.2 11.8 3.2 7.4 15.0 11.5 4.2 6.9 5.1 19.4 4.4 8.1 5.3 13.0 5.7 7.5 3.7 0.0 6.2 7.9 4.9 7.9 8.0 1.0 8.3 13.3 8.6 4.8 11.6 18.7 9.3 5.5 9.7 10.7 5.4 6.3 7.4 7.5 12.3 6.9 3.3 31.2 6.7 14.2 21.3 7.7 2.2 5.6 12.6 8.8 23.4 18.4 4.3 19.6 51.3 132.2 10.1 2.6 6.4 11.9 6.4 4.5 8.4 13.1 8.3 6.6 11.6 9.5 11.4 10.6 13.8 4.8 7.3 11.1 7.6 5.7 5.7 EPB41 "4.1R, EL1" ENSG00000159023 "Erythrocyte membrane protein band 4.1" P11171 1 28887091-29120046 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell cycle, Cell division, Mitosis, Transport" "Actin-binding, Calmodulin-binding" "Elliptocytosis, Hereditary hemolytic anemia, Pyropoikilocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 80.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 151.6;Cone photoreceptor cells: 137.6;Erythroid cells: 187.1;Rod photoreceptor cells: 171.4" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 42.2" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 136.3;K-562: 136.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 8 "cerebellum: 105.6" "HPA028076, HPA028096, HPA028412, HPA028414" Supported Supported "Nuclear bodies,Plasma membrane,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes No 1100000 "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cell Junctions" "Nuclear bodies, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA028076: AB_2672476, HPA028096: , HPA028412: AB_2672592, HPA028414: AB_10601366" "unprognostic (2.16e-1)" "unprognostic (1.96e-1)" "unprognostic (8.92e-3)" "prognostic unfavorable (4.58e-4)" "unprognostic (5.00e-2)" "prognostic favorable (5.87e-4)" "unprognostic (5.01e-3)" "unprognostic (5.40e-3)" "unprognostic (2.52e-2)" "unprognostic (6.65e-2)" "unprognostic (7.81e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (1.75e-6)" "unprognostic (2.66e-2)" "unprognostic (2.42e-1)" "unprognostic (1.22e-1)" "unprognostic (6.67e-2)" 11.0 10.2 1.8 21.9 18.3 63.3 14.1 42.2 6.0 14.5 4.9 23.6 17.7 10.2 5.3 16.6 6.3 15.0 9.7 1.2 4.7 12.7 21.7 15.1 37.4 8.2 5.6 16.3 18.8 15.5 4.7 7.2 8.5 15.0 23.1 80.0 19.1 9.1 15.9 15.3 23.3 9.9 3.5 22.9 27.0 10.4 4.7 69.0 15.2 13.8 37.0 15.5 1.9 3.0 27.0 6.9 62.3 29.4 5.2 0.8 19.5 6.9 10.1 8.4 10.5 16.8 31.2 49.1 17.2 9.2 13.5 11.9 78.7 6.6 8.6 86.4 23.8 136.3 19.7 28.6 10.1 45.8 88.2 1.7 18.4 8.2 13.8 19.9 14.1 73.5 136.5 36.2 0.1 8.8 72.3 30.4 62.0 44.1 10.0 110.9 28.2 68.3 7.7 33.3 78.0 60.5 19.7 19.2 43.3 21.7 14.7 18.2 1.2 0.3 13.3 12.9 13.4 52.5 72.4 85.2 12.1 47.8 6.8 33.3 3.2 21.4 12.9 1.1 15.4 17.2 18.3 14.1 4.4 13.6 22.1 12.7 44.2 10.9 1.5 4.4 28.9 15.3 1.8 18.3 42.2 6.0 1.2 4.7 8.2 5.6 8.5 3.5 4.7 3.0 25.3 19.2 71.7 20.2 58.2 10.5 8.6 7.8 15.4 151.6 20.0 12.2 21.5 20.0 16.8 16.5 137.6 2.4 75.3 26.5 17.6 17.1 16.4 11.3 4.1 15.1 41.6 187.1 76.3 18.7 4.2 7.9 29.6 29.1 24.1 24.9 17.5 30.0 7.1 21.9 61.7 29.0 16.2 23.7 9.0 22.7 2.1 32.4 0.0 78.7 29.3 15.7 85.5 7.5 4.8 28.6 20.3 2.2 46.7 12.2 32.8 13.4 15.2 171.4 13.1 2.8 8.5 39.3 55.7 14.9 16.8 4.1 71.6 4.2 33.0 12.6 EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 156.4;Inhibitory neurons: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "A549: 163.5;HaCaT: 237.9;OE19: 192.9;SK-BR-3: 185.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA054104: AB_2682380, HPA056817: AB_2683244" "unprognostic (2.01e-2)" "unprognostic (7.77e-2)" "unprognostic (1.76e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-2)" "unprognostic (3.87e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.30e-4)" "unprognostic (1.78e-1)" "prognostic favorable (4.39e-10)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.26e-2)" 55.1 122.1 68.6 8.1 73.8 0.4 25.7 66.0 97.2 37.7 0.0 31.2 13.8 27.9 31.0 46.3 45.3 40.3 21.3 64.7 81.7 64.7 8.9 30.1 4.4 101.5 80.3 41.8 29.3 37.0 21.1 21.8 94.0 26.9 20.9 39.5 56.6 42.6 12.0 14.2 16.7 27.2 53.0 8.1 64.2 18.3 75.0 4.5 24.8 15.4 14.0 40.7 31.7 79.9 53.5 163.5 57.7 21.5 36.8 22.8 53.8 16.8 37.7 35.1 27.9 108.7 93.7 3.0 26.4 52.7 71.7 237.9 26.7 19.6 26.2 0.5 14.9 0.4 52.7 107.6 11.3 0.2 19.4 19.9 9.4 32.9 2.7 44.7 8.6 13.0 2.7 41.5 30.5 34.2 1.8 0.9 21.4 192.9 49.9 2.6 16.0 66.3 30.5 84.6 20.1 24.5 74.9 185.6 6.4 43.9 45.8 2.4 7.3 40.9 43.0 20.8 3.7 50.3 19.0 0.6 71.2 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 68.6 73.8 66.0 97.2 64.7 81.7 101.5 80.3 94.0 53.0 75.0 79.9 14.5 16.0 22.1 27.7 0.4 2.9 5.0 11.1 30.7 31.9 12.8 9.4 8.5 28.6 16.5 47.8 156.4 1.5 0.8 23.8 19.6 22.2 2.9 10.6 8.7 9.2 15.5 0.0 56.8 10.8 0.5 11.0 50.4 7.5 52.5 13.3 10.0 3.7 6.9 32.0 75.7 6.0 4.1 1.3 2.2 2.7 15.8 6.0 3.6 3.7 0.0 22.7 0.0 24.6 73.1 31.6 15.7 42.2 2.1 5.1 8.0 37.1 21.9 8.7 32.9 6.8 35.1 4.6 7.1 43.2 1.7 1.1 0.8 7.1 13.2 18.0 EPB41L2 "4.1-G, 4.1G" ENSG00000079819 "Erythrocyte membrane protein band 4.1 like 2" O43491 6 130839347-131063322 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 368.5" "Cell type enhanced" "Detected in many" "Microglial cells: 433.8;Muller glia cells: 472.5;Rod photoreceptor cells: 1272.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005730, HPA006642" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 54000 "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA005730: AB_1848195, HPA006642: AB_1848194" "unprognostic (3.18e-2)" "unprognostic (1.04e-1)" "unprognostic (8.34e-3)" "unprognostic (3.40e-3)" "unprognostic (1.41e-1)" "unprognostic (5.17e-2)" "prognostic unfavorable (2.41e-5)" "unprognostic (1.25e-1)" "unprognostic (1.23e-1)" "prognostic unfavorable (2.16e-4)" "unprognostic (3.24e-1)" "unprognostic (1.63e-1)" "unprognostic (5.63e-2)" "unprognostic (3.64e-2)" "unprognostic (3.82e-1)" "unprognostic (3.48e-2)" "unprognostic (9.19e-2)" 121.0 35.0 57.8 40.9 108.2 10.0 50.1 62.4 90.2 41.4 6.0 59.1 27.5 49.2 24.1 28.6 55.2 39.6 52.5 57.5 58.2 24.3 26.7 58.6 37.7 101.3 65.5 92.6 20.2 14.8 18.0 58.8 102.1 23.6 49.7 368.5 23.3 32.9 38.7 16.0 47.8 43.1 66.8 59.7 26.6 74.5 73.4 30.7 33.7 67.8 26.4 36.0 34.8 120.8 34.0 35.6 78.0 109.5 53.4 85.7 23.9 56.4 72.2 57.9 79.9 67.5 47.7 41.7 102.9 79.6 46.6 17.1 30.6 53.2 114.2 178.4 70.9 74.0 42.5 38.5 31.5 0.1 87.4 42.3 1.1 101.7 38.8 91.8 89.3 62.5 206.1 115.8 37.2 8.5 59.4 13.1 72.6 146.3 38.5 90.9 94.4 4.0 96.5 31.9 8.4 0.3 23.7 0.7 45.4 80.1 12.2 78.3 108.9 66.9 125.0 113.6 172.1 95.6 1.7 38.5 45.8 0.5 103.8 0.1 2.9 0.5 0.9 8.0 0.8 2.5 0.9 1.1 8.2 8.4 1.4 0.6 0.0 1.1 3.2 2.2 2.6 1.2 57.8 108.2 62.4 90.2 57.5 58.2 101.3 65.5 102.1 66.8 73.4 120.8 132.5 6.4 12.0 150.5 17.0 15.4 13.3 5.3 24.5 63.1 10.2 19.9 16.5 21.5 16.0 1.8 225.2 4.4 4.8 54.7 0.0 32.7 332.6 72.3 83.3 92.9 10.2 5.9 300.9 16.6 5.7 120.5 9.7 113.2 44.3 100.3 43.9 5.4 33.5 28.6 144.0 41.9 0.0 166.7 63.3 332.1 73.0 50.8 10.6 433.8 14.0 472.5 2.1 119.1 288.8 57.9 25.0 46.3 10.2 6.2 28.0 10.4 11.2 1272.4 118.3 149.6 89.2 102.8 97.6 12.1 10.2 2.5 9.4 82.8 39.3 7.2 EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 171.9;Excitatory neurons: 306.8;Inhibitory neurons: 237.4;Late spermatids: 291.6;Oligodendrocytes: 159.2;Syncytiotrophoblasts: 214.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.4" "Lineage enriched" "Detected in many" 5 "monocytes: 12.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;HUVEC TERT2: 59.5;SCLC-21H: 65.5;TIME: 164.8;U-2 OS: 57.7;U-2197: 57.1;U-251 MG: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 27.6 28.1 5.8 27.4 5.3 4.1 11.7 17.9 49.9 6.4 0.0 17.7 49.6 7.8 5.6 10.7 13.6 9.3 6.5 7.1 24.8 33.9 4.8 13.9 7.9 59.6 14.7 11.4 6.9 59.6 10.4 21.1 53.3 5.8 13.1 45.8 4.0 7.3 6.1 4.0 47.7 13.4 7.7 12.2 3.2 62.3 29.1 6.5 4.6 10.7 3.9 10.3 5.7 29.8 0.3 0.9 3.9 0.0 54.5 62.8 43.7 12.8 0.0 0.0 0.0 0.7 0.1 0.1 0.1 39.8 23.2 0.2 38.6 0.0 0.0 0.0 34.2 0.1 0.4 0.0 0.2 0.1 4.6 33.3 0.0 12.3 0.1 16.2 59.5 0.0 0.4 0.4 0.1 0.0 0.5 0.7 7.9 0.2 12.5 0.3 0.0 0.2 0.4 4.8 65.5 0.5 0.1 0.5 25.9 31.2 0.7 4.8 164.8 0.3 57.7 57.1 71.6 0.1 0.1 0.0 0.2 5.4 6.8 0.0 4.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.7 0.0 12.4 0.0 0.0 0.7 5.8 5.3 17.9 49.9 7.1 24.8 59.6 14.7 53.3 7.7 29.1 29.8 18.2 19.2 6.4 28.7 1.3 15.9 4.1 0.0 3.4 75.6 5.3 1.7 3.5 2.8 1.9 7.3 77.2 98.6 0.2 44.0 15.6 0.4 171.9 2.2 10.1 21.9 9.1 3.2 306.8 0.7 44.2 27.7 0.0 2.1 0.0 0.0 7.1 0.8 58.8 3.3 237.4 10.0 0.0 82.2 66.7 291.6 22.4 81.9 10.6 103.0 50.9 3.3 2.1 44.2 159.2 0.8 8.3 7.9 1.6 3.8 91.2 68.4 1.6 14.7 0.0 3.0 13.1 2.7 11.5 2.3 8.4 214.0 2.6 0.2 12.3 1.7 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.9;pancreas: 149.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.8;Excitatory neurons: 79.7;Hepatocytes: 125.2;Proximal enterocytes: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 31.7;hTCEpi: 49.8;OE19: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" 21.0 9.7 6.0 4.5 8.7 0.0 15.3 2.0 12.2 4.1 11.8 57.6 47.6 1.2 17.9 1.5 10.8 4.2 8.8 10.7 6.4 6.4 88.9 6.3 0.2 2.7 5.3 13.8 149.1 11.1 1.6 2.5 3.7 7.6 56.7 3.0 26.9 9.1 6.1 15.5 51.9 1.9 7.2 0.1 30.6 7.5 10.9 0.6 44.7 0.7 1.6 2.2 3.4 4.3 8.7 10.8 0.7 0.8 0.8 0.0 31.7 1.1 0.4 3.7 1.9 18.5 8.5 0.0 2.3 1.0 8.9 13.9 21.5 11.5 3.9 9.2 5.1 0.0 3.4 26.5 2.2 0.4 0.0 0.3 49.8 1.5 17.0 1.1 0.2 8.0 0.3 0.0 5.2 22.3 0.4 0.2 13.8 62.8 15.7 0.0 0.0 0.6 12.9 13.1 13.1 1.4 3.4 22.2 0.0 6.3 5.2 0.1 0.5 7.5 7.6 2.5 3.1 0.1 0.1 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 8.7 2.0 12.2 10.7 6.4 2.7 5.3 3.7 7.2 10.9 4.3 0.2 6.4 5.1 2.6 0.4 11.5 5.4 6.0 1.2 7.5 22.7 10.4 18.5 20.0 9.6 7.3 0.0 4.1 0.0 134.8 0.0 3.5 11.7 23.8 2.3 0.8 51.6 0.0 79.7 20.8 2.1 2.5 26.0 20.7 0.0 6.2 5.0 125.2 0.6 38.7 58.9 51.4 12.2 1.6 1.5 1.9 13.4 0.4 1.8 3.7 0.0 1.9 0.0 12.1 3.8 10.2 54.4 2.6 0.0 7.2 79.2 0.8 39.2 1.1 0.0 0.8 1.0 1.4 17.2 0.9 24.0 1.9 0.5 6.8 46.5 6.5 EPB41L5 "BE37, FLJ12957, KIAA1548, LULU, LULU1, YMO1, YRT" ENSG00000115109 "Erythrocyte membrane protein band 4.1 like 5" Q9HCM4 2 120013077-120179119 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 55.5;MCF7: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037563, HPA037564" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA037563: AB_2675546, HPA037564: AB_2675547" "unprognostic (1.27e-2)" "unprognostic (2.15e-1)" "unprognostic (2.56e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-2)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (5.93e-2)" "unprognostic (8.76e-2)" "unprognostic (2.20e-2)" "unprognostic (9.51e-2)" "prognostic favorable (2.28e-6)" "unprognostic (1.99e-1)" "unprognostic (3.88e-1)" "unprognostic (9.59e-2)" "unprognostic (2.61e-1)" 5.7 6.0 9.0 3.0 7.3 1.0 15.7 43.4 10.6 7.2 4.5 9.9 14.0 7.5 5.8 8.8 12.8 7.4 6.3 7.1 11.1 32.7 56.8 29.9 2.5 8.9 11.1 11.6 26.2 25.1 8.2 9.8 9.0 12.4 8.8 27.8 15.3 6.1 10.1 8.3 11.7 6.5 8.7 2.5 9.1 30.5 12.4 3.6 32.9 8.9 6.6 6.1 8.4 8.1 18.0 6.1 23.8 18.5 16.4 11.8 20.8 3.8 3.7 7.8 7.0 55.5 11.7 0.3 12.9 4.8 9.7 12.1 32.4 14.9 11.5 3.6 10.1 5.2 2.8 31.1 19.1 2.3 5.3 10.6 27.6 14.6 10.4 6.7 22.1 10.4 12.4 1.3 15.6 83.4 4.3 7.9 21.5 8.3 5.6 0.0 7.1 5.0 24.2 17.1 12.3 23.5 16.5 29.0 8.2 32.5 14.0 4.3 18.4 0.7 11.2 12.3 3.9 1.9 3.5 9.2 2.0 0.1 4.5 0.1 0.5 0.6 0.4 0.1 0.1 1.7 0.4 0.4 0.1 1.3 1.1 0.8 0.7 0.6 0.3 0.0 0.2 0.4 9.0 7.3 43.4 10.6 7.1 11.1 8.9 11.1 9.0 8.7 12.4 8.1 6.0 218.0 41.9 61.0 11.1 24.5 28.9 9.7 21.6 33.9 28.0 14.1 13.2 24.3 22.5 33.1 25.0 14.9 4.3 20.6 21.5 18.8 38.0 25.8 12.6 6.8 15.5 5.7 68.4 22.3 12.1 13.1 56.1 45.8 0.0 12.0 17.9 54.2 3.2 8.4 79.8 12.7 22.4 2.1 6.8 20.6 9.0 2.8 14.2 26.2 1.1 15.8 0.0 89.5 25.9 23.2 21.7 9.4 5.9 29.1 20.9 29.0 17.5 35.7 19.7 11.7 9.8 43.5 48.6 18.3 21.7 26.4 6.2 5.7 12.9 39.4 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EPHA2 ECK ENSG00000142627 "EPH receptor A2" P29317 1 16124337-16156069 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation, Host-virus interaction" "Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cataract, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 147.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 202.3;Glandular and luminal cells: 182.9;Squamous epithelial cells: 156.3;Suprabasal keratinocytes: 248.3;Urothelial cells: 200.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 94 "plasmacytoid DC: 9.4" "Lineage enriched" "Detected in single" 94 "dendritic cells: 9.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 201.1;PC-3: 229.0;U-251 MG: 242.1;WM-115: 258.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" CAB010464 Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cell Junctions" NA Yes 12000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions" "Nuclear speckles, Golgi apparatus" "CAB010464: AB_631436" "unprognostic (9.41e-2)" "unprognostic (1.67e-1)" "unprognostic (4.13e-2)" "unprognostic (1.67e-2)" "unprognostic (6.22e-2)" "unprognostic (9.12e-2)" "unprognostic (5.24e-2)" "unprognostic (1.29e-3)" "unprognostic (2.52e-2)" "unprognostic (7.05e-3)" "unprognostic (1.52e-3)" "unprognostic (2.77e-1)" "unprognostic (2.65e-2)" "unprognostic (2.08e-1)" "unprognostic (1.73e-1)" "unprognostic (4.77e-3)" "unprognostic (4.40e-2)" 21.4 9.5 3.5 4.8 3.1 0.3 14.6 2.9 3.7 38.2 11.7 12.4 10.0 12.1 1.3 147.9 13.5 28.2 15.8 3.1 3.1 18.7 18.9 17.9 7.6 3.8 3.7 5.8 23.2 3.7 7.4 14.0 3.8 11.2 5.8 6.4 67.7 4.2 4.6 40.3 12.8 3.7 3.6 7.6 15.6 1.8 4.3 3.2 15.2 5.1 11.1 56.1 58.8 3.1 76.9 151.7 41.4 20.1 2.9 3.5 24.3 45.2 63.4 79.9 50.6 63.9 201.1 0.1 189.8 25.9 98.8 30.6 9.9 104.4 27.6 0.4 7.0 0.0 46.7 41.1 51.3 0.1 0.2 4.8 38.1 43.7 95.6 125.0 86.4 0.0 0.3 0.1 51.6 24.3 0.0 0.0 20.0 57.2 229.0 0.1 37.6 0.2 85.1 39.0 0.1 6.4 87.8 21.2 6.1 21.3 3.0 0.9 108.1 28.5 76.7 2.0 242.1 0.0 0.5 0.6 22.0 0.1 258.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 3.5 3.1 2.9 3.7 3.1 3.1 3.8 3.7 3.8 3.6 4.3 3.1 17.1 54.5 38.4 2.0 1.2 202.3 114.3 110.9 66.0 2.7 39.5 43.9 6.5 44.3 113.4 9.2 4.2 9.7 8.9 96.8 0.0 33.8 5.8 104.5 19.2 26.3 3.0 0.0 0.1 14.2 1.2 5.8 68.3 182.9 5.7 0.4 29.3 23.3 1.9 0.0 0.2 42.0 34.6 1.6 17.0 0.2 3.4 3.7 26.6 4.7 1.1 7.1 0.0 0.0 0.0 104.6 111.7 0.0 0.0 60.8 22.4 1.8 89.8 2.5 32.9 11.6 21.2 0.2 0.8 156.3 248.3 7.5 2.6 0.4 42.9 200.4 EPHA3 "ETK, ETK1, HEK, HEK4, TYRO4" ENSG00000044524 "EPH receptor A3" P29320 3 89107621-89482134 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 31.5" "Group enriched" "Detected in some" 4 "Excitatory neurons: 70.6;Inhibitory neurons: 106.6;Microglial cells: 103.0;Oligodendrocytes: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AF22: 197.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB010462, HPA069390" Approved Supported "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear membrane, Plasma membrane, Cytosol" "Nucleoplasm, Actin filaments" "CAB010462: AB_2099218, HPA069390: " "unprognostic (1.48e-3)" "unprognostic (2.30e-2)" "unprognostic (4.95e-2)" "unprognostic (1.90e-1)" "unprognostic (2.96e-2)" "unprognostic (1.47e-2)" "unprognostic (2.03e-1)" "unprognostic (9.10e-3)" "unprognostic (1.24e-3)" "unprognostic (7.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (3.28e-7)" "unprognostic (3.63e-2)" "unprognostic (1.88e-2)" "unprognostic (4.05e-2)" "unprognostic (1.20e-2)" 5.4 1.0 2.1 1.8 1.3 0.0 2.3 0.2 3.8 12.3 0.1 3.8 2.3 5.5 0.2 3.2 1.3 18.8 8.2 2.2 0.7 1.3 4.9 2.4 3.6 3.3 0.9 4.1 2.1 1.0 0.9 20.1 4.0 31.5 6.2 8.0 2.2 7.1 0.8 0.7 2.4 7.9 0.8 0.9 2.5 1.0 1.7 1.0 11.0 6.3 3.2 14.3 6.4 2.2 0.0 0.0 197.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.0 0.0 11.2 0.2 0.7 0.0 2.4 0.0 0.0 11.8 0.0 0.0 1.7 2.0 0.0 3.9 0.0 0.0 0.6 0.0 2.5 0.1 0.3 0.0 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.1 0.0 0.5 0.1 0.1 36.1 0.1 0.0 0.0 1.7 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.2 3.8 2.2 0.7 3.3 0.9 4.0 0.8 1.7 2.2 2.2 0.0 0.0 5.5 0.0 0.5 0.3 0.0 0.6 6.4 0.0 0.1 2.4 0.0 0.0 0.0 2.1 0.2 0.0 0.0 0.0 0.0 1.8 0.0 0.5 1.8 0.0 0.0 70.6 0.0 0.1 18.1 0.5 0.0 0.0 0.0 1.1 0.0 0.1 20.2 106.6 0.0 0.0 0.0 0.7 1.6 2.1 0.1 0.0 103.0 0.0 4.7 0.0 2.5 48.0 0.0 0.0 8.2 0.0 0.1 0.0 0.0 0.0 18.7 6.6 0.7 19.2 0.1 0.0 0.3 0.3 0.5 0.2 1.3 0.0 0.1 EPHB1 "EPHT2, Hek6" ENSG00000154928 "EPH receptor B1" P54762 3 134597801-135260467 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 40.6" "Cell type enhanced" "Detected in many" "Astrocytes: 198.8;dendritic cells: 53.7;Early spermatids: 42.2;Excitatory neurons: 47.9;Inhibitory neurons: 44.3;Late spermatids: 41.2;Oligodendrocyte precursor cells: 77.9" "Cancer enriched" "Detected in many" 6 "glioma: 7.0" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 33 "neutrophil: 24.0;plasmacytoid DC: 23.3" "Group enriched" "Detected in many" 33 "dendritic cells: 23.3;granulocytes: 24.0" "Group enriched" "Detected in some" 5 "HDLM-2: 63.9;HMC-1: 35.5;RPTEC TERT1: 16.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067740 Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA067740: AB_2685895" "unprognostic (1.99e-1)" "unprognostic (3.45e-1)" "unprognostic (2.52e-1)" "unprognostic (1.41e-6)" "unprognostic (6.52e-2)" "unprognostic (1.31e-1)" "unprognostic (1.07e-1)" "unprognostic (8.15e-2)" "unprognostic (9.88e-2)" "unprognostic (1.55e-1)" "unprognostic (1.11e-1)" "unprognostic (1.75e-1)" "unprognostic (1.04e-1)" "unprognostic (4.82e-2)" "unprognostic (1.78e-1)" "unprognostic (1.37e-3)" "unprognostic (4.88e-4)" 1.0 0.6 4.7 0.8 18.7 0.7 3.2 40.6 12.8 1.8 0.0 3.2 1.4 2.2 0.9 1.9 1.3 1.7 0.3 7.0 5.1 1.3 1.6 0.3 1.9 5.0 14.4 0.7 0.3 0.2 1.0 0.2 5.5 1.7 0.5 4.2 2.2 2.7 4.9 4.8 0.7 0.7 0.9 1.9 0.6 10.8 12.0 0.7 7.0 10.3 1.7 1.5 1.0 4.2 0.0 0.0 8.4 0.1 0.2 0.0 0.0 6.6 0.1 0.3 0.1 0.1 0.0 1.1 1.6 3.4 0.6 0.1 5.5 0.0 1.2 63.9 0.8 4.8 0.0 0.0 0.0 0.0 35.5 0.1 0.0 0.1 0.0 0.3 0.2 0.5 0.0 0.3 4.7 0.2 0.0 0.3 2.4 1.2 0.1 0.0 0.9 0.2 16.5 0.0 1.1 0.2 0.0 0.1 0.0 1.1 0.1 0.7 0.5 1.1 3.4 0.7 7.9 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 23.3 0.0 0.2 4.7 18.7 40.6 12.8 7.0 5.1 5.0 14.4 5.5 0.9 12.0 4.2 1.9 0.0 0.0 198.8 1.0 3.7 0.0 0.0 0.0 1.9 0.8 12.3 1.6 0.0 0.0 0.0 10.4 0.0 53.7 0.0 0.0 0.8 42.2 0.1 0.5 2.8 0.0 0.0 47.9 0.4 0.1 0.4 0.0 0.1 0.0 3.3 0.4 7.0 0.4 0.0 44.3 0.0 0.0 0.0 0.8 41.2 0.6 0.8 1.8 8.4 0.1 16.9 0.0 77.9 5.6 0.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.5 0.0 3.3 0.8 0.5 1.6 0.0 5.8 0.0 0.2 3.0 0.3 0.2 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPN1 ENSG00000063245 "Epsin 1" Q9Y6I3 19 55675226-55709858 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 387.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 263.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009729, HPA061136, HPA071503" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" No No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Nucleoplasm, Vesicles" "CAB009729: AB_2277865, HPA061136: AB_2684436, HPA071503: " "unprognostic (6.93e-2)" "unprognostic (2.47e-1)" "unprognostic (5.30e-2)" "unprognostic (1.32e-1)" "unprognostic (7.94e-2)" "unprognostic (8.76e-2)" "unprognostic (1.23e-2)" "unprognostic (7.23e-3)" "unprognostic (1.18e-1)" "unprognostic (1.28e-1)" "unprognostic (6.16e-2)" "unprognostic (4.63e-2)" "unprognostic (1.05e-2)" "unprognostic (3.86e-3)" "unprognostic (1.57e-1)" "unprognostic (2.78e-3)" "unprognostic (7.92e-3)" 57.1 75.3 63.1 27.3 61.2 22.1 53.0 30.3 82.2 51.1 14.8 73.1 88.7 47.8 9.2 80.5 48.7 14.3 148.6 65.2 31.5 85.2 137.1 50.5 19.3 37.8 38.5 76.2 104.3 22.3 51.1 17.4 31.1 64.8 16.2 8.9 50.9 20.0 156.1 71.0 80.4 11.0 27.9 72.8 152.6 80.8 40.0 11.6 49.0 35.3 11.2 50.1 54.5 47.1 95.5 128.8 31.5 64.8 35.6 33.8 64.6 69.3 39.0 48.2 48.0 54.1 58.7 58.1 46.1 55.6 42.5 71.5 27.7 52.9 17.4 20.4 263.2 42.8 67.4 65.3 48.9 27.8 39.3 43.9 45.6 41.7 30.1 34.7 46.4 40.7 64.7 48.0 32.2 53.6 44.4 45.2 72.3 71.4 179.6 29.5 42.8 103.2 36.8 55.3 45.2 109.9 64.1 68.8 48.0 21.7 51.6 95.7 78.4 133.0 63.8 48.4 101.3 52.2 50.9 41.7 97.9 55.0 67.5 1.4 1.8 2.3 0.6 2.2 0.4 1.0 0.6 0.6 1.1 0.8 0.6 0.6 2.1 0.3 3.6 1.7 0.9 1.5 63.1 61.2 30.3 82.2 65.2 31.5 37.8 38.5 31.1 27.9 40.0 47.1 62.6 3.2 20.4 9.8 44.2 31.4 29.0 25.9 44.3 33.3 32.7 25.8 15.5 55.8 17.9 44.1 66.7 46.1 28.1 227.7 119.3 57.1 63.2 39.5 37.5 46.1 45.0 35.3 7.8 88.5 80.8 37.2 145.2 45.9 10.8 87.0 83.9 106.1 62.9 28.6 7.8 115.6 22.4 136.5 21.4 169.4 47.5 55.4 23.2 6.5 40.8 33.6 28.8 4.5 8.9 106.5 167.7 53.0 57.7 37.6 387.2 81.8 20.9 41.3 13.1 41.2 34.6 50.2 62.7 46.6 27.4 52.3 26.3 48.2 132.5 39.2 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 37.8" "Cell type enriched" "Detected in some" 10 "Early spermatids: 739.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" 0.2 0.0 0.4 0.0 1.2 0.0 0.2 0.8 0.6 0.2 0.2 0.3 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.0 0.3 0.2 1.5 0.9 0.5 0.4 0.0 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.8 0.2 0.2 37.8 1.6 0.0 0.2 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.8 0.6 0.2 0.4 1.5 0.9 1.3 0.8 1.6 2.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 739.3 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 67.8 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.7 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 16.2 2.4 0.0 0.3 0.1 0.0 0.1 0.2 0.1 ERAP1 "A-LAP, ARTS-1, ERAAP1, KIAA0525, PILS-AP" ENSG00000164307 "Endoplasmic reticulum aminopeptidase 1" Q9NZ08 5 96760810-96808100 "Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Adaptive immunity, Immunity" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 72.8;Inhibitory neurons: 79.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025095, HPA042317" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 30000000 "Cluster 34: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB025095: , HPA042317: AB_2677946" "unprognostic (2.33e-3)" "unprognostic (3.45e-1)" "unprognostic (1.84e-3)" "unprognostic (1.34e-1)" "unprognostic (1.86e-1)" "unprognostic (4.38e-1)" "unprognostic (1.88e-3)" "unprognostic (5.37e-2)" "unprognostic (1.45e-1)" "unprognostic (7.94e-2)" "unprognostic (4.52e-2)" "unprognostic (3.23e-1)" "unprognostic (7.09e-2)" "unprognostic (1.36e-1)" "unprognostic (3.93e-2)" "unprognostic (1.19e-1)" "unprognostic (5.14e-2)" 51.5 15.8 3.7 37.0 4.3 27.9 25.5 3.1 5.6 21.8 2.3 37.9 63.4 22.0 14.4 13.2 25.5 23.7 17.1 3.4 5.2 16.4 32.9 31.2 38.2 8.4 5.7 20.7 13.7 19.1 8.2 47.0 7.0 18.6 43.7 12.4 19.3 22.0 20.9 36.5 55.1 21.7 5.0 30.8 33.7 9.1 6.6 63.7 17.5 19.6 36.8 27.3 11.7 6.8 25.9 14.1 21.3 20.0 114.7 111.5 61.4 18.3 59.6 44.0 76.2 17.6 91.1 75.3 37.6 36.0 61.8 25.7 17.8 38.1 27.3 139.8 7.5 24.7 10.0 13.9 130.9 12.0 44.1 46.8 16.2 50.6 15.5 64.3 61.1 48.8 12.9 74.7 26.7 11.6 113.2 12.4 10.6 3.1 10.4 82.4 28.8 38.4 32.8 39.0 7.8 5.5 29.6 19.8 28.6 14.6 17.1 57.0 48.8 37.4 12.6 6.2 31.1 26.9 53.9 57.8 40.2 40.2 22.5 28.8 15.2 18.0 22.6 12.3 20.2 14.8 19.2 19.1 10.5 18.3 22.3 18.1 15.8 23.1 20.6 16.7 13.9 13.7 3.7 4.3 3.1 5.6 3.4 5.2 8.4 5.7 7.0 5.0 6.6 6.8 11.1 9.6 16.3 34.0 15.3 25.0 14.2 19.2 8.6 13.6 6.6 3.9 10.6 10.0 16.9 9.2 2.1 9.6 21.1 24.4 0.0 12.4 27.0 12.7 15.0 16.3 10.3 14.1 72.8 15.5 11.9 18.4 16.3 19.8 15.2 13.9 16.8 28.0 17.6 3.3 79.3 23.9 4.1 29.9 16.1 7.3 9.9 22.9 7.2 24.4 32.5 9.0 20.6 32.6 70.1 12.3 14.1 16.1 32.3 13.5 47.3 6.9 23.1 7.6 0.0 10.3 22.6 1.4 1.8 9.8 11.1 9.2 21.8 5.7 27.3 14.9 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in many" 41 "OE19: 6565.0;SK-BR-3: 3115.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 13.0 5.4 16.1 12.1 20.5 1.6 56.0 14.3 13.1 37.6 23.3 68.2 63.6 25.2 26.6 102.4 64.2 31.0 57.0 13.3 16.0 73.5 31.1 36.2 4.8 22.4 22.7 23.9 37.6 81.7 17.3 27.0 17.1 55.6 48.5 8.1 68.7 50.5 20.7 91.0 67.3 25.0 18.5 6.9 49.7 11.7 15.4 7.4 56.5 15.0 28.0 40.0 52.9 16.4 38.7 45.7 50.4 31.7 59.3 41.2 67.7 27.2 44.9 58.6 48.9 34.4 102.7 2.9 54.6 62.7 31.5 117.6 2.8 61.2 26.9 5.2 38.6 1.8 36.0 56.3 35.3 0.9 1.0 41.0 56.6 36.2 21.9 56.2 24.4 1.9 6.2 2.4 43.3 59.4 7.1 3.0 90.7 6565.0 11.7 3.9 20.5 5.4 58.9 118.9 9.4 2.6 51.5 3115.9 16.9 62.2 88.1 2.2 2.9 30.2 37.7 37.7 17.6 5.3 3.3 3.6 3.0 0.9 98.5 1.1 0.2 0.4 5.0 0.1 0.3 0.6 0.2 1.4 0.2 0.6 0.5 1.4 1.2 0.4 0.1 0.1 0.2 1.7 16.1 20.5 14.3 13.1 13.3 16.0 22.4 22.7 17.1 18.5 15.4 16.4 3.9 41.7 40.1 12.7 2.2 14.0 19.0 37.1 17.6 4.6 62.7 34.9 20.7 32.9 43.8 136.1 12.5 12.0 5.1 111.0 7.9 30.9 0.3 48.7 13.9 6.1 15.6 1.3 0.9 25.5 84.8 15.7 53.5 61.3 0.0 20.3 11.7 10.7 4.0 6.7 1.0 47.5 42.7 2.2 3.1 1.0 18.3 1.7 10.6 1.0 1.2 24.1 26.8 2.0 1.0 32.5 54.8 23.0 1.1 34.9 121.7 19.5 42.0 5.8 0.0 13.1 12.7 6.8 5.7 43.5 18.9 22.7 2.8 4.4 75.4 31.3 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERC1 "CAST2, ELKS, KIAA1081, MGC12974, RAB6IP2" ENSG00000082805 "ELKS/RAB6-interacting/CAST family member 1" Q8IUD2 12 990509-1495933 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 292.3;Horizontal cells: 185.1;Inhibitory neurons: 487.0;Microglial cells: 213.6;Oligodendrocyte precursor cells: 230.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019513, HPA019523, HPA024130" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Vesicles, Plasma membrane" "HPA019513: AB_1856012, HPA019523: AB_1856013, HPA024130: AB_1856014" "unprognostic (2.41e-1)" "unprognostic (4.00e-2)" "unprognostic (2.14e-1)" "unprognostic (5.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (5.50e-2)" "unprognostic (8.49e-2)" "unprognostic (2.53e-1)" "unprognostic (3.26e-2)" "unprognostic (1.04e-1)" "unprognostic (6.79e-2)" "unprognostic (3.75e-3)" "unprognostic (4.19e-2)" "unprognostic (3.01e-1)" "unprognostic (7.37e-2)" "prognostic unfavorable (7.01e-4)" 10.4 9.7 12.2 6.8 14.4 7.3 8.0 38.1 12.8 8.9 8.0 11.8 3.5 9.0 4.8 11.8 8.2 7.5 13.9 15.2 18.5 9.2 6.5 7.3 4.8 13.7 14.8 10.5 7.6 15.4 8.1 11.8 13.7 9.5 6.2 7.0 8.4 12.1 9.4 9.4 5.8 12.9 11.9 5.8 7.2 7.5 17.7 7.9 13.4 9.0 5.3 13.4 9.0 12.6 8.2 20.1 10.3 7.1 27.8 22.2 14.2 25.0 20.0 17.0 15.3 17.7 10.0 12.5 3.4 33.2 16.8 13.3 22.1 19.7 23.1 25.9 11.6 30.3 20.1 9.3 21.1 16.1 6.9 18.7 17.0 30.0 55.6 20.7 22.3 7.9 9.6 23.9 12.9 9.2 5.2 3.5 16.8 8.1 9.7 9.9 38.9 3.8 16.9 14.2 6.3 12.3 38.8 9.3 13.9 37.6 9.3 7.0 39.6 29.6 29.0 21.6 24.0 6.4 13.1 18.1 19.2 9.4 12.9 1.5 3.1 2.3 1.7 1.2 2.4 12.7 2.7 2.7 2.7 5.6 3.8 2.7 2.4 1.4 4.8 3.4 2.8 0.7 12.2 14.4 38.1 12.8 15.2 18.5 13.7 14.8 13.7 11.9 17.7 12.6 36.9 25.6 25.1 155.4 21.2 21.0 25.6 9.4 29.0 39.2 13.2 14.1 56.4 17.2 17.4 20.2 47.9 34.1 12.6 12.7 1.9 20.3 34.3 31.2 43.4 34.6 30.0 7.6 292.3 13.4 18.0 32.3 23.9 53.9 14.5 59.2 24.3 17.3 12.4 185.1 487.0 11.9 2.0 12.6 16.5 35.2 24.8 17.0 14.2 213.6 18.4 34.8 6.2 230.7 171.1 18.5 10.3 30.9 39.1 30.8 6.1 4.1 13.2 33.4 19.7 35.5 33.1 18.5 28.8 33.8 27.4 78.7 15.8 18.7 10.3 29.4 ERCC4 "FANCQ, RAD1, XPF" ENSG00000175595 "ERCC excision repair 4, endonuclease catalytic subunit" Q92889 16 13920154-13952348 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair" "DNA-binding, Endonuclease, Hydrolase, Nuclease" "Cancer-related genes, Cockayne syndrome, Disease variant, Dwarfism, Fanconi anemia, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 18.5" "Cell type enhanced" "Detected in many" "Early spermatids: 140.7;Late spermatids: 117.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000156, HPA045828" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "CAB000156: , HPA045828: AB_2679463" "unprognostic (2.05e-1)" "unprognostic (1.52e-1)" "unprognostic (2.12e-3)" "unprognostic (9.41e-2)" "unprognostic (3.35e-1)" "unprognostic (1.40e-2)" "unprognostic (1.64e-2)" "unprognostic (2.26e-1)" "unprognostic (3.59e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (8.49e-2)" "unprognostic (5.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.15e-1)" "unprognostic (6.30e-2)" "unprognostic (5.88e-4)" 2.7 3.9 4.7 3.3 5.2 2.5 2.8 6.7 5.4 3.3 4.3 1.9 1.7 3.3 2.8 2.9 3.5 3.0 3.6 4.3 4.9 2.9 3.2 2.7 3.3 5.1 4.8 4.3 2.7 3.9 1.6 2.6 4.9 3.6 2.2 4.1 2.8 2.9 18.5 3.0 1.9 3.6 4.4 3.7 2.6 5.5 5.4 4.2 4.4 3.3 2.9 2.6 1.5 6.8 4.7 5.5 5.3 7.5 8.7 8.1 4.0 6.1 6.4 5.4 6.8 2.1 4.5 7.8 8.6 5.4 4.8 5.8 8.0 4.1 8.3 10.7 4.7 3.8 6.7 5.2 7.9 5.2 4.2 6.1 5.7 7.1 6.0 5.3 7.2 4.6 6.1 8.8 7.6 3.9 7.0 3.4 3.9 2.4 3.1 7.8 10.8 9.7 3.3 3.2 4.3 5.1 7.5 6.0 5.8 4.2 7.5 3.9 7.9 7.8 5.7 7.0 5.4 7.9 9.9 5.2 7.6 6.2 8.1 4.9 2.3 2.3 2.6 2.7 2.9 2.5 2.4 2.0 2.3 3.1 2.4 2.6 2.7 3.6 2.4 3.2 2.5 1.1 4.7 5.2 6.7 5.4 4.3 4.9 5.1 4.8 4.9 4.4 5.4 6.8 14.0 19.2 13.5 16.6 11.3 4.8 6.1 18.3 10.2 0.0 10.0 9.5 8.6 14.3 12.7 5.5 0.0 17.3 9.7 3.3 9.8 11.6 140.7 18.6 19.0 13.5 9.6 12.0 20.4 8.4 6.2 13.0 5.1 7.4 1.3 17.8 17.2 17.7 11.7 0.0 21.2 4.8 10.2 13.6 6.5 117.9 14.9 11.4 10.6 8.4 14.4 0.0 17.5 12.1 20.1 9.9 1.7 21.1 14.4 10.2 4.4 13.3 26.1 0.0 26.3 17.3 12.2 49.4 28.9 9.2 5.5 12.3 11.8 18.0 6.0 4.7 ERMN "ERMIN, JN, KIAA1189" ENSG00000136541 Ermin Q8TAM6 2 157318631-157327713 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 498.6;choroid plexus: 136.2" "Cell type enriched" "Detected in some" 51 "Oligodendrocytes: 290.9" "Cancer enriched" "Detected in some" 4 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HAP1: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038295, HPA038296" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "HPA038295: AB_10805353, HPA038296: AB_10796217" "unprognostic (7.89e-2)" "unprognostic (9.06e-3)" "unprognostic (2.71e-2)" "prognostic favorable (6.93e-6)" "unprognostic (1.06e-1)" "unprognostic (2.02e-2)" "unprognostic (9.14e-2)" "unprognostic (1.79e-1)" "unprognostic (4.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.07e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-3)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (9.97e-3)" "unprognostic (5.76e-2)" 0.7 0.2 212.4 2.3 342.3 18.8 0.5 312.8 386.9 0.5 136.2 0.7 0.5 0.4 0.1 0.4 0.4 0.8 0.3 208.7 266.4 0.5 0.5 2.4 3.3 408.3 313.2 0.2 0.3 0.0 0.4 0.1 391.8 0.3 0.9 0.6 1.7 0.3 0.4 0.7 3.8 0.3 266.5 4.7 1.3 0.5 300.8 1.6 0.4 0.0 3.0 0.7 0.3 498.6 0.1 0.3 0.3 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 1.3 0.0 1.9 0.0 0.3 25.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 3.5 0.4 0.2 0.7 2.3 0.2 0.1 0.5 0.0 0.4 0.5 0.0 1.0 0.4 0.5 0.0 0.1 0.0 0.3 0.6 1.2 0.0 0.2 0.1 0.3 0.6 3.4 2.5 0.6 1.7 0.9 0.9 0.5 0.3 0.3 0.4 0.2 0.2 0.1 0.1 0.1 0.1 0.3 0.3 0.3 0.6 0.5 0.2 0.3 0.2 0.1 212.4 342.3 312.8 386.9 208.7 266.4 408.3 313.2 391.8 266.5 300.8 498.6 0.1 0.0 1.3 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.3 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.8 0.2 0.0 1.2 0.9 0.1 0.0 2.2 0.0 1.9 1.1 0.0 3.1 2.0 290.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 2.7 0.0 0.0 0.0 ERVFRD-1 "envFRD, ERVFRDE1, HERV-FRD, HERV-W/FRD, syncytin-2" ENSG00000244476 "Endogenous retrovirus group FRD member 1, envelope" P60508 6 11102489-11111725 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "placenta: 37.0" "Cell type enriched" "Detected in some" 56 "Syncytiotrophoblasts: 575.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 38.8" HPA011812 Uncertain "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Actin filaments" "Nucleoplasm, Cytosol" "HPA011812: AB_1857702" "unprognostic (1.99e-1)" "unprognostic (3.29e-4)" "unprognostic (4.75e-2)" "unprognostic (1.80e-1)" "unprognostic (1.34e-1)" "unprognostic (2.19e-3)" "unprognostic (3.35e-1)" "unprognostic (6.44e-2)" "unprognostic (1.24e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-2)" "unprognostic (2.78e-3)" "unprognostic (5.80e-4)" "unprognostic (3.40e-2)" "unprognostic (1.82e-1)" "unprognostic (1.95e-2)" "unprognostic (1.37e-2)" 0.3 0.4 0.6 0.1 0.4 0.2 0.4 1.8 0.6 0.4 0.0 0.3 0.5 0.3 1.0 0.3 0.2 0.4 0.1 0.6 0.7 0.5 0.2 0.6 0.0 0.6 0.4 0.0 0.0 7.5 0.0 37.0 0.5 0.3 0.2 0.2 0.2 0.2 0.0 0.5 0.5 0.2 0.1 0.0 0.3 0.1 0.6 0.4 0.0 0.4 0.0 0.5 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.4 1.8 0.6 0.6 0.7 0.6 0.4 0.5 0.1 0.6 0.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.1 0.3 0.0 0.0 10.1 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.1 0.0 0.0 0.0 575.5 0.4 0.5 0.0 0.0 ESAM W117m ENSG00000149564 "Endothelial cell adhesion molecule" Q96AP7 11 124752583-124762290 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 405.9;Endothelial cells: 301.0;Hepatic stellate cells: 138.1;Sertoli cells: 151.2;Smooth muscle cells: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 8.2;naive B-cell: 7.5" "Group enriched" "Detected in many" 9 "B-cells: 7.5;granulocytes: 8.2;T-cells: 2.2" "Group enriched" "Detected in many" 10 "HEL: 218.8;HUVEC TERT2: 277.9;TIME: 142.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056293, HPA072563" Uncertain Approved "Cell Junctions,Cytosol" NA NA 82000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Cell Junctions" Cytosol "HPA056293: AB_2683089, HPA072563: " "unprognostic (1.52e-1)" "unprognostic (2.03e-1)" "unprognostic (1.05e-2)" "unprognostic (3.56e-1)" "unprognostic (1.41e-2)" "unprognostic (4.49e-3)" "unprognostic (2.61e-1)" "unprognostic (1.10e-1)" "unprognostic (9.05e-2)" "unprognostic (2.99e-2)" "unprognostic (3.08e-1)" "unprognostic (3.60e-1)" "unprognostic (1.54e-1)" "unprognostic (1.24e-2)" "unprognostic (5.10e-2)" "unprognostic (2.29e-1)" "unprognostic (5.06e-2)" 97.5 17.7 38.4 9.0 37.7 1.9 79.4 38.8 46.9 33.3 30.1 20.0 7.0 36.2 7.8 21.8 34.2 20.0 83.0 35.2 38.7 63.6 11.5 112.5 8.7 40.9 38.9 14.4 13.6 13.2 14.8 106.9 44.0 19.8 7.8 2.5 15.6 15.6 27.1 18.2 20.9 29.4 37.3 17.3 23.4 4.3 45.4 5.4 95.9 49.8 8.3 30.8 30.2 37.8 1.2 1.6 0.4 1.2 0.0 0.3 5.1 0.1 0.1 0.0 0.1 2.7 14.1 1.2 3.2 0.0 0.2 0.0 3.7 0.0 0.0 1.8 1.3 218.8 0.1 8.0 0.6 0.4 3.6 0.0 0.0 0.0 0.0 0.2 277.9 0.1 0.2 5.9 0.5 1.8 0.0 0.0 0.6 20.8 2.1 0.0 1.0 0.9 0.0 2.4 0.2 0.8 0.1 16.1 0.0 7.5 3.3 0.8 142.0 0.4 0.4 0.5 0.0 0.2 0.2 0.2 0.1 0.5 0.4 8.2 0.6 0.0 0.1 0.3 0.0 2.1 1.5 0.1 0.4 7.5 2.2 0.8 6.5 0.0 0.0 0.4 0.4 24.8 38.4 37.7 38.8 46.9 35.2 38.7 40.9 38.9 44.0 37.3 45.4 37.8 405.9 38.5 56.0 2.0 4.5 15.2 0.5 0.2 2.8 18.5 2.5 3.2 11.2 0.0 3.0 14.7 4.2 1.8 2.5 3.5 5.9 7.6 5.0 1.1 1.5 301.0 0.0 5.3 1.5 2.4 18.7 13.8 3.6 1.4 3.8 0.1 138.1 1.7 1.1 0.0 0.4 0.4 0.0 5.3 22.1 26.3 0.9 25.7 12.4 20.6 1.2 0.7 0.0 0.5 0.4 46.5 2.1 0.4 2.8 1.8 0.1 0.1 1.9 1.3 151.2 4.6 89.4 0.1 0.9 0.8 10.9 37.1 2.0 2.4 1.6 2.3 ESCO2 "EFO2, RBS" ENSG00000171320 "Establishment of sister chromatid cohesion N-acetyltransferase 2" Q56NI9 8 27771949-27812640 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle" "Acyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.0;intestine: 11.0;lymphoid tissue: 8.5;testis: 5.7" "Group enriched" "Detected in many" 4 "Erythroid cells: 44.6;Spermatocytes: 62.0;Spermatogonia: 80.0" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 1.3" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA027243, HPA053679" Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes Yes "Cluster 4: T-regs - Cell cycle regulation" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Golgi apparatus" "Cell Junctions" "HPA027243: AB_2672175, HPA053679: AB_2682227" "unprognostic (7.86e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.04e-4)" "unprognostic (5.13e-3)" "unprognostic (9.50e-2)" "unprognostic (8.67e-3)" "unprognostic (7.30e-4)" "unprognostic (5.24e-3)" "unprognostic (2.24e-2)" "unprognostic (2.54e-2)" "unprognostic (7.51e-4)" "unprognostic (2.23e-1)" "unprognostic (1.65e-14)" "unprognostic (6.65e-3)" "unprognostic (5.32e-1)" "unprognostic (5.85e-2)" "unprognostic (4.06e-1)" 0.5 0.4 0.0 2.7 0.2 6.0 1.2 0.4 0.2 0.5 0.0 3.7 11.0 0.6 0.0 2.4 0.2 0.6 0.2 0.0 0.0 0.1 0.7 0.4 4.6 0.0 0.0 0.1 1.0 0.3 0.0 1.1 0.1 0.3 4.3 0.5 0.3 0.1 0.0 1.1 7.9 0.7 0.0 0.8 2.5 5.7 0.0 8.5 0.3 0.2 5.7 0.8 0.5 0.2 54.6 39.9 17.9 22.0 2.3 3.9 10.2 31.6 12.9 27.8 32.5 14.2 10.7 21.0 16.6 8.3 24.7 29.2 22.0 8.5 43.6 15.8 9.2 24.4 16.2 15.3 0.3 12.5 21.4 0.7 0.9 17.0 4.2 3.0 11.6 15.2 20.0 30.0 17.7 10.5 49.8 5.9 12.2 29.9 13.4 21.7 53.0 14.8 9.6 31.9 8.0 11.7 15.5 19.6 7.9 6.5 13.2 14.1 5.2 17.9 37.0 36.2 25.7 4.0 11.1 25.2 10.2 20.5 25.2 0.0 0.2 0.1 0.0 0.4 0.0 0.4 0.2 0.2 0.6 0.0 0.1 0.1 0.2 0.3 0.1 0.0 1.3 0.3 0.0 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.0 4.7 0.0 2.4 2.3 0.6 2.1 1.8 1.2 1.5 1.7 1.2 0.0 3.3 0.0 4.2 4.6 1.3 8.2 0.0 0.4 5.4 1.3 2.6 1.0 1.2 44.6 0.3 0.0 6.6 3.2 5.6 3.1 1.3 11.4 1.4 1.5 5.4 0.0 0.4 4.4 2.0 2.5 3.5 0.8 1.8 3.2 0.0 1.0 0.5 0.1 4.1 1.0 0.9 0.1 1.5 0.0 11.5 0.6 15.1 0.1 1.6 2.0 6.6 0.8 2.3 62.0 80.0 6.8 0.6 1.0 3.1 1.8 8.0 1.4 ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 185.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 24000 "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA002132: AB_1078807, HPA070823: " "unprognostic (2.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (5.72e-2)" "unprognostic (5.43e-2)" "unprognostic (9.01e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.13e-1)" "unprognostic (7.54e-2)" "unprognostic (6.70e-2)" "unprognostic (4.58e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (2.81e-5)" 53.9 37.0 24.0 25.6 25.0 34.8 33.9 21.8 28.7 30.8 22.7 38.4 22.3 36.1 30.1 45.0 34.4 32.2 35.1 27.7 25.3 27.2 24.5 33.4 27.5 22.1 24.6 48.1 29.2 30.9 20.6 43.3 24.6 25.3 30.3 14.2 32.1 30.5 44.9 31.0 27.6 38.7 21.7 21.4 25.5 15.8 30.7 37.0 39.3 41.8 25.4 35.8 29.3 19.4 92.9 57.8 19.5 19.8 62.2 72.6 55.3 47.5 48.9 36.7 40.6 29.7 106.1 27.5 52.2 86.2 66.6 46.0 27.8 50.2 35.1 31.5 28.3 26.2 44.0 32.2 64.1 95.0 55.8 53.4 51.8 41.8 55.2 73.1 44.8 81.9 56.4 97.8 61.9 71.7 96.0 66.7 29.2 53.9 56.7 82.4 37.0 38.8 58.6 38.4 46.8 30.2 151.6 109.7 66.7 43.4 37.7 96.3 69.3 40.3 18.8 178.7 60.5 68.6 17.3 27.5 102.4 93.8 121.5 1.7 1.4 1.2 6.1 1.8 3.4 1.1 5.1 4.3 2.8 0.6 4.6 5.5 0.9 5.4 1.2 1.8 4.2 2.3 24.0 25.0 21.8 28.7 27.7 25.3 22.1 24.6 24.6 21.7 30.7 19.4 65.7 38.5 32.4 55.5 18.1 46.1 12.9 22.6 19.4 15.0 32.6 21.6 30.8 21.5 33.7 47.8 16.7 31.6 54.0 41.0 3.9 15.3 18.0 60.6 17.8 48.5 21.1 17.7 137.1 20.0 26.1 44.2 15.8 47.0 12.6 36.8 23.2 20.9 20.2 13.5 119.3 31.2 24.4 20.2 83.6 5.3 35.1 27.7 51.6 185.5 21.9 12.1 43.3 67.3 61.4 29.9 14.1 54.5 36.2 23.2 28.0 8.7 61.8 10.8 32.9 42.6 60.4 10.6 10.2 22.0 51.7 40.8 43.4 19.5 26.0 25.8 ETNK1 "EKI, EKI1" ENSG00000139163 "Ethanolamine kinase 1" Q9HBU6 12 22625075-22690665 "Cancer-related genes, Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 299.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010712, HPA029407" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 5: NTERA-2 - Transcription" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA010712: AB_2668349, HPA029407: AB_2673026" "unprognostic (2.06e-1)" "unprognostic (7.48e-2)" "unprognostic (1.23e-3)" "unprognostic (2.19e-1)" "unprognostic (8.79e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (5.85e-4)" "unprognostic (3.98e-3)" "unprognostic (8.30e-2)" "unprognostic (7.97e-3)" "unprognostic (2.01e-1)" "unprognostic (1.64e-2)" "unprognostic (4.53e-3)" "unprognostic (2.77e-1)" "unprognostic (2.91e-1)" "unprognostic (3.01e-1)" "prognostic favorable (1.75e-4)" 10.1 14.4 13.7 14.5 15.2 12.2 13.7 9.0 15.9 10.8 16.4 27.2 23.3 10.2 19.6 10.8 10.1 14.0 7.3 14.7 28.1 18.4 18.2 12.6 17.4 12.0 14.2 11.7 10.7 10.8 13.7 11.3 15.8 10.9 15.3 18.2 12.4 6.2 6.2 15.3 15.5 7.6 11.1 16.7 45.0 17.8 19.3 23.1 14.5 5.6 14.3 10.8 9.5 17.5 14.8 27.9 30.4 27.5 21.2 21.3 21.7 15.6 12.2 17.4 16.0 20.6 33.3 41.1 14.7 11.6 16.5 10.7 27.1 7.6 28.2 36.8 23.7 34.7 11.5 18.9 20.6 33.9 29.4 13.7 7.2 21.9 17.4 25.8 20.3 15.7 41.8 17.2 22.3 7.7 38.8 67.1 59.3 17.9 20.1 32.7 28.1 32.9 25.6 16.5 9.8 17.8 18.9 13.9 27.1 41.1 24.1 32.1 17.5 12.2 19.9 18.6 25.0 12.9 18.1 46.8 16.2 21.0 23.9 44.0 14.3 15.9 15.4 22.0 15.2 22.2 16.4 14.4 14.1 15.3 17.7 17.7 14.6 17.7 23.4 12.6 20.5 19.2 13.7 15.2 9.0 15.9 14.7 28.1 12.0 14.2 15.8 11.1 19.3 17.5 33.6 48.1 32.2 48.0 55.9 144.3 75.7 34.7 64.9 41.0 56.8 42.2 10.1 45.8 43.8 44.1 50.1 30.1 57.6 116.1 27.4 30.7 299.0 64.2 49.1 34.8 108.3 48.8 104.4 44.5 24.2 38.2 230.4 51.4 34.8 40.9 28.2 41.5 42.9 26.9 104.3 60.7 46.8 88.3 60.0 43.5 24.2 57.0 67.6 84.3 39.1 17.7 43.3 121.2 152.9 39.5 62.9 21.4 63.7 73.8 57.7 33.2 81.6 39.5 39.5 23.3 38.9 49.1 18.5 51.9 170.2 75.4 49.0 41.5 47.8 90.3 ETS2 ENSG00000157557 "ETS proto-oncogene 2, transcription factor" P15036 21 38805183-38824955 "Predicted intracellular proteins, RAS pathway related proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 701.0;Basal squamous epithelial cells: 863.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 33.6;granulocytes: 37.0;monocytes: 32.4" "Cell line enhanced" "Detected in many" "HEL: 309.0;hTCEpi: 269.6;hTERT-HME1: 210.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003176 Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA003176: AB_2666824" "unprognostic (2.06e-1)" "unprognostic (5.91e-2)" "unprognostic (9.16e-3)" "unprognostic (5.33e-3)" "unprognostic (1.38e-1)" "unprognostic (1.58e-1)" "unprognostic (1.88e-3)" "unprognostic (7.36e-2)" "unprognostic (8.99e-3)" "unprognostic (3.66e-2)" "unprognostic (1.02e-1)" "unprognostic (1.77e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-1)" "unprognostic (1.89e-1)" "unprognostic (8.10e-2)" "unprognostic (7.10e-2)" 109.9 29.7 51.4 95.5 43.3 167.1 87.7 31.6 72.5 89.6 61.4 119.3 131.3 77.5 27.9 90.6 72.5 132.1 68.0 50.9 43.2 66.1 230.7 185.5 38.0 50.0 39.9 65.7 37.5 61.9 56.6 73.6 45.0 80.1 146.5 7.5 50.3 45.7 149.7 248.3 179.7 78.0 47.9 201.0 72.7 7.6 54.0 43.7 62.5 42.8 34.8 210.2 103.6 44.4 120.1 26.2 16.6 5.6 18.8 61.3 49.2 27.4 154.1 36.2 46.5 23.0 35.1 24.7 13.3 25.0 48.5 35.7 28.0 71.2 63.8 24.5 12.0 309.0 152.6 62.2 196.9 18.4 28.2 39.8 269.6 49.6 210.2 22.0 28.3 17.2 31.3 0.2 14.4 20.1 54.1 22.2 56.0 39.3 18.2 189.6 10.2 25.2 50.2 74.4 14.2 18.4 78.4 32.8 6.2 5.7 1.9 36.3 30.8 83.0 13.0 55.3 60.5 0.5 0.3 25.2 20.7 69.4 70.8 21.0 19.5 7.0 3.2 24.9 3.9 0.4 3.0 4.7 33.6 0.4 3.2 3.2 37.0 0.3 32.4 8.1 0.3 8.9 51.4 43.3 31.6 72.5 50.9 43.2 50.0 39.9 45.0 47.9 54.0 44.4 253.0 51.3 156.6 6.2 10.8 427.4 701.0 150.8 863.4 2.1 84.2 69.7 25.6 51.5 141.9 51.5 0.0 58.4 17.5 150.7 11.7 73.7 4.0 241.1 127.4 312.7 91.8 36.4 39.6 108.5 109.3 98.7 161.1 497.9 51.3 0.9 242.0 262.4 62.1 0.0 10.7 266.0 79.3 150.8 291.7 2.0 18.0 253.4 67.6 74.0 41.0 1.5 3.1 4.0 3.1 127.6 175.1 24.8 21.0 184.0 162.2 47.2 107.9 1.6 52.6 81.8 108.8 0.6 3.3 522.6 486.4 177.6 28.8 8.2 243.3 338.7 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 233.2;Kupffer cells: 522.3;Langerhans cells: 169.8;Macrophages: 271.9;monocytes: 426.4;T-cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Cell line enhanced" "Detected in many" "Daudi: 87.9;HL-60: 99.9;HMC-1: 133.3;Karpas-707: 96.4;NB-4: 79.4;RPMI-8226: 147.7;THP-1: 124.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" 24.6 11.0 6.4 100.9 7.3 189.0 13.8 7.3 11.6 13.1 8.7 27.9 23.7 7.4 4.3 11.8 7.8 30.5 6.7 6.3 8.4 5.1 24.9 61.1 159.5 13.3 10.3 5.5 3.0 3.8 1.8 15.4 10.8 7.4 30.5 1.2 11.8 6.1 2.0 5.1 39.2 17.0 7.7 158.8 33.7 3.7 8.5 76.4 5.3 12.2 169.8 38.5 4.1 11.1 0.6 0.7 0.0 0.0 6.5 8.3 0.1 0.8 5.8 6.7 12.4 0.0 3.4 87.9 0.1 5.5 26.4 0.6 0.0 1.2 7.5 0.1 0.0 2.1 0.0 0.0 66.0 99.9 133.3 15.3 0.0 3.9 5.3 2.2 6.9 7.3 1.4 96.4 19.8 0.0 29.4 79.4 0.1 0.0 0.0 51.0 0.4 147.7 0.3 0.2 0.0 0.1 0.4 0.2 0.5 0.0 0.0 124.8 7.2 1.9 0.2 0.7 7.0 18.4 0.9 18.9 8.6 34.0 2.2 1005.3 328.9 798.7 79.2 240.1 76.8 183.6 120.8 102.8 149.9 146.2 91.9 87.5 1366.0 44.2 381.9 86.3 173.6 251.4 6.4 7.3 7.3 11.6 6.3 8.4 13.3 10.3 10.8 7.7 8.5 11.1 2.1 0.0 14.8 0.7 233.2 5.4 0.7 0.7 1.8 0.2 1.5 1.7 1.0 2.8 6.7 1.8 0.0 0.6 129.0 1.3 0.0 0.3 8.3 0.1 0.3 5.6 0.0 6.5 2.7 0.0 0.8 4.0 1.5 0.4 82.2 0.0 7.5 2.3 89.1 0.0 3.1 0.1 2.0 522.3 169.8 9.0 0.0 271.9 37.4 11.2 426.4 0.0 117.4 4.0 31.7 1.0 0.0 0.4 110.4 0.4 0.1 1.1 2.4 0.8 19.7 1.2 1.9 0.4 0.4 0.4 3.7 0.3 170.9 0.0 1.3 1.1 EXOC1 "BM-102, FLJ10893, SEC3, SEC3L1, Sec3p" ENSG00000090989 "Exocyst complex component 1" Q9NV70 4 55853648-55905086 "Predicted intracellular proteins, Transporters" "Antiviral defense, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037706, HPA044873" Uncertain Approved "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Microtubules, Cytosol" "HPA037706: AB_10670525, HPA044873: AB_2679125" "unprognostic (7.10e-3)" "unprognostic (4.48e-2)" "unprognostic (8.85e-2)" "unprognostic (9.22e-2)" "unprognostic (9.81e-2)" "unprognostic (2.63e-1)" "prognostic unfavorable (2.63e-4)" "unprognostic (2.84e-3)" "unprognostic (4.65e-2)" "unprognostic (2.04e-2)" "unprognostic (4.03e-3)" "unprognostic (1.55e-1)" "unprognostic (1.94e-1)" "unprognostic (3.11e-1)" "unprognostic (2.93e-2)" "unprognostic (6.24e-2)" "prognostic favorable (5.50e-5)" 19.7 16.5 18.1 17.3 20.4 12.7 20.0 20.4 20.0 18.9 18.7 18.0 16.8 16.6 20.4 29.3 16.5 15.5 16.5 18.3 20.0 15.9 10.2 17.4 18.3 21.1 19.2 15.1 12.9 20.5 14.5 20.8 20.3 14.3 19.1 18.5 17.4 12.8 13.6 28.1 16.2 15.7 20.4 20.8 15.6 16.9 20.1 13.9 16.3 13.5 20.0 16.2 20.1 25.1 21.8 12.4 21.9 25.3 36.9 45.9 14.6 30.2 30.1 24.1 25.1 8.6 37.1 20.9 20.6 32.6 29.1 25.4 18.0 23.9 34.5 11.1 12.4 19.4 14.8 10.1 34.7 21.3 26.4 37.4 32.1 25.1 27.6 31.2 39.9 16.0 28.3 20.1 53.0 13.8 15.6 21.5 13.9 31.2 23.4 18.0 16.4 17.1 26.9 23.6 16.2 28.7 18.0 29.2 25.5 18.5 18.6 22.6 48.5 29.7 24.2 25.8 26.3 23.9 12.7 18.4 38.6 23.4 28.8 21.3 14.6 13.1 6.5 19.0 8.8 8.4 9.2 9.5 14.3 8.3 8.3 6.0 19.5 12.5 23.6 6.4 11.6 7.9 18.1 20.4 20.4 20.0 18.3 20.0 21.1 19.2 20.3 20.4 20.1 25.1 44.7 41.7 38.0 77.4 24.5 34.8 14.8 34.0 22.2 48.8 26.4 21.2 29.1 17.2 35.6 22.0 31.3 60.8 21.4 38.3 19.6 23.6 45.3 41.0 47.5 39.0 22.2 19.6 72.6 20.0 31.6 28.9 22.4 37.2 36.7 35.5 40.0 12.3 40.9 28.6 86.5 28.8 24.4 37.7 47.4 16.7 21.5 37.8 40.9 56.2 38.7 40.3 22.6 73.4 138.0 36.2 32.4 23.7 19.0 17.4 37.6 21.9 44.7 32.5 32.9 25.9 27.9 47.6 31.6 42.5 39.9 51.2 27.8 44.6 28.7 26.8 EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 26.4;Endothelial cells: 19.6;Granulosa cells: 20.8;Hepatic stellate cells: 28.9;Leydig cells: 15.5;Peritubular cells: 18.4;Theca cells: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HUVEC TERT2: 3.5;SCLC-21H: 6.4;SuSa: 2.1;TIME: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" 6.4 4.6 0.5 1.8 0.5 0.0 4.1 1.0 0.8 2.6 0.0 1.6 0.9 2.8 0.1 1.3 1.8 1.1 5.4 0.5 0.5 7.3 2.1 10.0 1.4 0.8 0.2 3.6 1.6 0.8 2.0 5.9 1.1 2.4 0.4 0.2 1.6 0.6 2.1 1.2 1.7 0.9 0.1 44.7 1.5 2.1 0.4 0.1 7.1 0.8 0.2 1.7 1.3 0.1 0.1 0.0 0.7 0.2 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.8 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 3.5 0.4 0.3 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.4 0.8 0.7 0.1 0.0 0.1 6.4 0.8 0.8 0.1 0.0 2.1 0.6 0.0 2.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.5 0.5 1.0 0.8 0.5 0.5 0.8 0.2 1.1 0.1 0.4 0.1 26.4 0.0 0.0 0.3 0.3 0.9 2.1 2.8 5.7 1.5 3.0 5.2 1.6 0.0 0.4 3.7 0.0 0.6 0.2 4.6 7.9 1.0 2.0 0.1 0.3 19.6 1.2 2.7 0.1 3.7 4.3 2.6 1.5 0.4 0.0 20.8 28.9 1.4 0.8 3.3 0.3 3.4 2.0 1.9 0.2 5.5 15.5 1.8 0.0 1.0 4.0 0.3 0.0 1.0 0.0 0.6 3.1 18.4 0.0 0.4 8.9 0.2 0.3 0.9 0.0 0.3 1.1 4.0 8.6 1.2 2.0 0.8 0.2 32.5 2.7 1.6 EXOC7 "BLOM4, EXO70, Exo70p, KIAA1067, YJL085W" ENSG00000182473 "Exocyst complex component 7" Q9UPT5 17 76081016-76121576 "Human disease related genes, Predicted intracellular proteins, Transporters" "Exocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022840, HPA022842" Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" Cytosol "Vesicles, Plasma membrane" "HPA022840: AB_1848316, HPA022842: AB_1848317" "unprognostic (5.20e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (3.49e-2)" "unprognostic (2.37e-2)" "unprognostic (1.88e-1)" "unprognostic (1.30e-1)" "unprognostic (1.02e-1)" "unprognostic (2.47e-2)" "unprognostic (7.39e-3)" "unprognostic (1.53e-2)" "unprognostic (1.73e-1)" "unprognostic (1.19e-1)" "unprognostic (1.05e-1)" "unprognostic (1.18e-1)" 40.4 31.4 36.0 32.7 37.0 53.2 31.2 31.4 36.7 39.3 34.1 40.1 32.5 40.1 33.1 52.3 52.3 35.4 47.2 36.8 35.5 31.9 30.2 35.9 32.7 35.4 34.3 49.6 41.1 61.2 41.0 35.3 36.5 48.1 27.9 24.7 50.6 43.1 43.0 37.0 34.7 43.5 31.9 32.4 30.3 24.9 36.4 43.5 43.0 41.4 32.3 44.3 30.1 34.8 65.6 79.4 71.9 58.5 66.6 47.0 74.5 58.9 77.6 103.9 74.7 67.5 43.0 33.7 42.0 103.0 65.6 52.7 43.9 57.1 69.0 29.3 59.1 55.8 64.0 72.3 46.4 62.9 55.7 66.1 44.3 80.5 39.2 73.5 116.9 59.8 38.1 33.7 65.6 59.8 102.1 27.8 37.8 49.5 83.4 54.0 123.3 34.6 59.7 133.6 38.9 91.4 66.5 48.6 44.6 68.8 79.7 51.0 77.5 111.3 66.3 74.1 65.8 46.0 18.2 31.2 66.4 28.0 59.0 55.1 41.1 66.1 35.5 57.4 24.4 26.7 26.9 30.4 28.9 26.9 27.7 23.9 46.2 36.4 79.7 12.3 32.0 44.9 36.0 37.0 31.4 36.7 36.8 35.5 35.4 34.3 36.5 31.9 36.4 34.8 31.0 19.2 35.0 36.6 37.7 19.8 40.1 40.8 31.3 87.6 30.2 28.8 7.5 28.6 41.4 40.5 143.9 51.5 37.5 47.6 33.2 38.3 22.4 35.1 25.8 27.1 48.9 48.6 26.2 37.1 29.0 31.6 27.0 34.4 41.1 65.0 30.7 27.0 37.7 67.3 31.1 43.8 54.9 29.6 21.3 52.2 37.3 26.9 24.9 15.0 36.8 52.1 56.7 44.2 35.0 44.6 41.4 38.4 15.7 41.5 62.8 35.3 43.7 108.8 46.0 27.8 49.5 32.1 16.6 20.3 19.9 71.1 35.8 56.6 29.8 44.8 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 F11R "CD321, JAM-1, JAM-A, JAM1, JAMA, JCAM, PAM-1" ENSG00000158769 "F11 receptor" Q9Y624 1 160995211-161021343 "CD markers, Plasma proteins, Predicted membrane proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 253.2;Urothelial cells: 242.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 165.5;neutrophil: 113.4" "Lineage enriched" "Detected in all" 5 "granulocytes: 165.5" "Cell line enhanced" "Detected in many" "HaCaT: 205.4;OE19: 202.4;SuSa: 232.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004671, HPA043616, HPA061700" Enhanced Supported "Cell Junctions,Microtubules" NA NA 1900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 22: Epithelial cell types - Mixed function" Microtubules "Cell Junctions" "CAB004671: AB_425964, HPA043616: , HPA061700: AB_2684589" "unprognostic (1.60e-2)" "unprognostic (5.78e-3)" "unprognostic (1.78e-3)" "unprognostic (2.24e-1)" "unprognostic (4.99e-2)" "unprognostic (4.89e-2)" "unprognostic (2.28e-1)" "unprognostic (2.55e-1)" "unprognostic (6.35e-2)" "unprognostic (1.98e-3)" "unprognostic (1.87e-2)" "unprognostic (1.24e-1)" "unprognostic (1.78e-1)" "unprognostic (2.50e-1)" "unprognostic (1.59e-1)" "unprognostic (9.72e-3)" "unprognostic (5.01e-2)" 21.1 24.5 6.6 20.8 6.3 21.3 26.8 6.0 8.2 24.2 9.6 52.6 55.9 11.9 21.1 85.5 33.1 28.7 12.8 6.3 6.5 40.4 73.6 67.1 13.2 7.8 7.5 14.0 41.7 36.3 18.8 50.7 7.5 28.7 51.7 2.2 49.4 21.2 6.1 48.2 64.0 9.0 7.2 21.5 52.6 13.0 8.6 16.5 39.2 6.3 32.0 52.2 44.1 7.1 122.9 15.5 4.7 1.4 3.3 0.2 95.5 0.6 0.1 4.0 4.1 113.5 155.9 8.9 78.6 0.2 22.6 205.4 25.3 105.2 6.4 6.9 17.8 25.8 6.2 52.3 4.8 24.2 72.6 1.4 132.5 0.6 32.7 24.1 98.6 18.8 35.6 2.5 0.6 53.5 7.6 13.6 80.1 202.4 21.9 11.3 0.0 39.2 67.2 94.4 34.3 8.8 29.2 123.4 26.2 232.8 132.6 41.7 58.8 0.3 3.0 0.4 1.2 28.2 59.3 3.1 18.0 23.4 7.5 34.6 31.0 165.5 12.6 16.3 6.7 4.7 11.7 8.0 24.6 2.9 11.1 8.8 113.4 8.2 13.0 18.7 5.7 25.1 6.6 6.3 6.0 8.2 6.3 6.5 7.8 7.5 7.5 7.2 8.6 7.1 27.7 253.2 137.2 0.0 9.8 35.2 119.7 86.2 64.3 0.9 35.0 15.5 3.3 67.2 136.2 77.3 2.1 78.6 10.2 154.9 7.9 76.8 7.2 120.8 13.9 41.5 62.2 10.3 2.7 71.0 176.2 9.1 66.8 150.9 18.3 13.7 34.2 68.8 31.0 0.0 1.1 71.5 46.8 14.4 25.5 2.1 2.1 24.7 8.8 7.5 48.7 1.5 13.4 3.0 0.4 91.4 114.1 0.7 10.8 135.3 82.5 12.6 178.8 2.4 0.0 5.1 6.2 13.4 2.9 102.3 50.6 63.1 12.3 8.1 50.7 242.0 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.0;lung: 33.4;thyroid gland: 19.2" "Cell type enriched" "Detected in some" 4 "Adipocytes: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HEL: 30.7;HMC-1: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" 19.0 2.6 0.7 1.5 0.7 1.3 18.0 1.9 0.7 1.1 1.2 4.3 1.5 1.6 1.6 1.5 1.5 2.8 5.6 0.6 0.7 9.8 0.5 33.4 2.3 0.5 0.6 0.8 9.3 1.1 2.7 1.0 0.5 1.4 1.3 1.2 1.2 0.5 3.2 3.1 4.9 1.0 0.0 1.3 5.0 1.7 1.2 0.4 19.2 0.6 0.9 1.9 1.2 1.3 0.3 0.3 0.8 0.4 0.1 0.2 0.9 0.4 0.1 0.2 0.2 0.5 0.8 0.6 0.6 0.3 0.3 0.6 0.2 0.3 0.3 0.4 0.4 30.7 1.3 0.5 0.2 0.3 11.6 0.0 0.1 0.3 0.2 0.4 0.9 0.6 2.5 1.1 0.2 0.5 0.4 2.9 0.4 0.4 0.3 0.3 0.2 1.0 0.3 0.6 0.5 0.3 0.3 0.2 0.1 0.7 0.6 2.0 1.2 0.6 0.6 0.4 0.3 0.5 0.4 0.6 0.3 0.5 0.4 3.3 0.9 0.7 0.9 0.4 0.8 1.6 1.0 0.8 0.3 1.8 1.4 1.3 2.2 1.8 0.6 1.7 0.8 1.4 0.7 0.7 1.9 0.7 0.6 0.7 0.5 0.6 0.5 0.0 1.2 1.3 110.4 0.0 1.1 0.0 0.3 0.4 0.3 0.3 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.9 27.5 0.0 0.8 0.0 0.5 0.0 2.7 0.0 0.2 7.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.0 0.6 0.0 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.4 0.5 0.1 0.3 0.2 0.3 FAAP20 "C1orf86, FLJ31031" ENSG00000162585 "FA core complex associated protein 20" Q6NZ36 1 2184461-2212720 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 337.5;Proximal tubular cells: 290.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038829 Uncertain Supported "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Nuclear bodies, Cell Junctions" "HPA038829: AB_10673476" "unprognostic (1.36e-2)" "unprognostic (2.86e-2)" "unprognostic (2.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.64e-1)" "unprognostic (6.11e-2)" "prognostic unfavorable (4.57e-4)" "unprognostic (2.81e-1)" "unprognostic (1.36e-1)" "unprognostic (1.80e-1)" "prognostic favorable (2.88e-4)" "unprognostic (1.59e-1)" "unprognostic (1.96e-3)" "unprognostic (1.36e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (8.55e-2)" 39.3 57.5 18.1 3.2 18.9 5.6 41.2 20.8 28.0 52.5 20.5 48.5 4.6 50.0 1.3 38.8 37.8 1.5 50.0 14.5 19.6 64.8 52.1 37.9 3.6 24.6 18.9 45.3 38.7 5.1 75.5 3.2 19.6 61.1 1.8 3.7 30.7 7.1 26.4 42.7 31.8 1.8 20.2 45.0 47.3 54.8 26.9 2.9 52.9 4.0 3.1 43.7 40.7 18.9 27.7 4.4 5.8 7.3 3.6 4.7 34.8 30.4 11.0 9.6 12.9 6.7 18.0 31.7 43.7 4.8 9.0 13.5 4.2 4.6 4.9 68.3 61.0 26.5 6.8 14.4 13.5 18.7 24.8 8.1 9.8 5.8 6.3 5.9 11.9 24.6 37.1 7.6 6.7 11.6 27.0 57.6 20.8 5.4 55.6 36.0 18.1 30.7 4.6 4.5 47.4 63.5 19.8 8.6 58.5 5.3 8.5 7.5 25.6 15.1 35.8 18.7 17.4 68.9 39.9 48.2 28.0 11.4 6.4 9.8 16.4 63.4 18.4 16.9 18.1 28.3 16.5 19.8 17.0 25.7 22.2 18.6 20.6 10.8 15.6 42.4 16.2 10.6 18.1 18.9 20.8 28.0 14.5 19.6 24.6 18.9 19.6 20.2 26.9 18.9 71.7 6.4 11.9 0.0 82.3 0.0 97.7 0.0 79.6 29.1 120.9 138.2 22.1 62.9 6.8 97.5 4.2 119.7 83.6 14.5 170.2 128.5 102.7 44.3 77.2 62.1 43.7 36.8 0.0 110.8 144.1 65.3 64.7 49.9 7.6 74.8 84.6 94.5 134.0 15.2 0.0 56.0 0.0 110.8 0.0 337.5 86.0 82.3 0.0 0.0 178.9 84.7 91.6 0.0 0.0 141.1 40.8 82.8 60.9 152.8 56.2 290.1 8.0 29.5 65.7 63.3 68.8 101.5 38.3 88.4 0.0 89.8 62.4 102.5 42.2 113.2 FABP2 I-FABP ENSG00000145384 "Fatty acid binding protein 2" P12104 4 119317250-119322138 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 173 "intestine: 550.0" "Cell type enriched" "Detected in some" 10 "Proximal enterocytes: 5965.8" "Group enriched" "Detected in some" 9 "colorectal cancer: 3.2;pancreatic cancer: 1.6;stomach cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "basophil: 1.6;neutrophil: 4.2" "Lineage enriched" "Detected in single" 9 "granulocytes: 4.2" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RPMI-8226: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA034607, CAB047325, CAB047326" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 61000 "Cluster 1: Neutrophils - Mixed function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 24: NB-4 - Immune response" "Cluster 45: Enterocytes - Digestion" "Actin filaments, Cytosol" "Plasma membrane" "CAB047325: , CAB047326: , HPA034607: AB_10601317" "unprognostic (3.94e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (4.58e-1)" "unprognostic (1.51e-2)" "unprognostic (2.61e-2)" "unprognostic (1.69e-4)" "unprognostic (1.93e-1)" "unprognostic (1.02e-1)" 0.2 0.1 0.1 3.1 0.1 0.9 0.0 0.6 0.2 0.0 0.4 28.2 291.0 0.3 0.1 0.1 0.2 0.1 0.6 0.2 0.1 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 35.2 0.3 0.0 0.0 0.1 0.4 550.0 1.9 0.0 0.1 0.7 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.1 0.3 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.2 0.1 0.0 0.0 1.6 0.4 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.1 0.2 0.2 0.2 4.2 0.4 0.1 0.3 0.3 0.0 0.1 0.1 0.6 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.7 0.0 0.0 1.8 0.0 0.0 0.0 242.0 0.0 0.0 0.0 1.4 0.1 0.1 1.2 0.0 0.0 0.2 0.1 0.3 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 570.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 383.1 0.0 0.0 0.0 5965.8 17.3 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 222.5 0.0 FABP3 "FABP11, H-FABP, MDGI, O-FABP" ENSG00000121769 "Fatty acid binding protein 3" P05413 1 31365253-31376850 "Candidate cardiovascular disease genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 14 "heart muscle: 5666.1;skeletal muscle: 2202.5;tongue: 1442.4" "Cell type enhanced" "Detected in many" "Breast glandular cells: 629.8;Cardiomyocytes: 2495.2;Distal tubular cells: 452.0;Proximal tubular cells: 703.6" "Cancer enhanced" "Detected in all" "renal cancer: 92.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "ASC TERT1: 215.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017830, HPA055754" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Focal adhesion sites" NA NA 1640000 3000000 "Cluster 22: NK-cells - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 30: Mammary glandular cells - Lactation" "Focal adhesion sites" "Golgi apparatus, Plasma membrane" "CAB017830: , HPA055754: AB_2682909" "unprognostic (2.07e-2)" "unprognostic (2.50e-2)" "unprognostic (1.32e-3)" "unprognostic (1.73e-2)" "unprognostic (2.05e-1)" "unprognostic (1.62e-1)" "unprognostic (6.07e-3)" "unprognostic (1.04e-1)" "unprognostic (6.86e-2)" "unprognostic (1.18e-1)" "unprognostic (2.85e-1)" "unprognostic (1.67e-1)" "prognostic favorable (1.54e-7)" "unprognostic (5.80e-3)" "unprognostic (3.45e-1)" "unprognostic (7.38e-3)" "unprognostic (9.76e-3)" 31.4 63.5 33.7 2.1 39.2 1.6 95.4 42.3 51.5 40.4 14.8 16.3 0.8 93.9 6.4 9.5 37.2 3.7 5666.1 52.0 37.3 229.8 6.6 26.4 3.4 50.5 38.3 20.3 2.2 0.3 9.0 2.8 55.2 48.9 4.8 17.8 46.5 52.2 2202.5 16.3 7.5 44.2 31.4 28.8 60.3 15.3 36.1 2.3 6.8 1442.4 1.4 12.5 32.5 36.8 1.0 0.4 8.8 1.1 50.6 215.0 2.0 2.6 17.3 0.3 6.6 1.3 1.9 1.6 17.8 5.2 0.3 2.1 2.5 0.0 0.5 0.8 3.7 1.8 2.7 5.3 2.2 1.7 0.5 16.9 0.0 3.9 0.0 2.5 0.0 1.4 2.2 0.5 2.2 0.5 0.7 1.5 11.4 0.9 3.1 0.4 5.7 0.6 4.1 0.7 2.1 0.5 1.5 0.7 28.4 13.2 0.9 3.1 1.7 1.0 1.0 6.0 1.3 1.0 2.3 1.3 2.9 1.5 1.7 0.0 0.1 0.0 0.2 0.2 0.2 0.2 0.1 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.1 0.1 0.1 0.1 33.7 39.2 42.3 51.5 52.0 37.3 50.5 38.3 55.2 31.4 36.1 36.8 4.9 0.0 1.7 2.9 7.7 3.6 1.5 0.4 0.0 6.1 629.8 13.2 2495.2 2.8 1.3 27.6 2.1 3.8 2.1 0.4 452.0 0.4 2.5 0.4 0.5 25.6 0.0 0.0 16.1 0.4 1.4 67.2 1.1 3.1 1.3 43.8 2.2 0.1 114.7 8.4 14.6 0.1 0.0 27.8 10.3 5.4 6.8 19.1 8.8 3.7 0.0 2.6 0.0 3.5 8.9 0.3 12.3 7.9 0.1 6.8 0.1 703.6 1.5 10.2 0.0 14.9 40.7 2.9 0.2 0.2 3.0 1.6 5.1 97.9 0.3 36.5 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM126B "HYCC2, MGC39518" ENSG00000155744 "Family with sequence similarity 126 member B" Q8IXS8 2 200973718-201071671 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 164.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in all" 4 "neutrophil: 25.7" "Lineage enriched" "Detected in all" 6 "granulocytes: 25.7" "Cell line enhanced" "Detected in all" "U-266/84: 58.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036166, HPA036167, HPA067307" Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Cell Junctions" Nucleoplasm "HPA036166: AB_10696651, HPA036167: AB_2674982, HPA067307: AB_2685821" "unprognostic (7.47e-3)" "unprognostic (5.54e-2)" "unprognostic (2.52e-1)" "unprognostic (9.08e-2)" "unprognostic (8.96e-2)" "unprognostic (3.01e-3)" "unprognostic (1.11e-2)" "unprognostic (2.61e-3)" "unprognostic (1.34e-1)" "unprognostic (1.48e-2)" "unprognostic (1.79e-2)" "unprognostic (1.90e-2)" "unprognostic (1.06e-1)" "unprognostic (1.19e-1)" "unprognostic (2.44e-1)" "unprognostic (1.34e-1)" "unprognostic (1.10e-2)" 7.8 4.5 4.7 6.3 5.2 17.4 4.8 15.9 8.1 4.0 2.3 7.2 6.8 3.9 4.0 8.2 3.2 4.3 3.4 6.5 3.1 7.8 7.4 5.4 5.9 3.3 3.2 3.8 4.9 4.9 3.8 5.0 3.3 3.7 6.4 10.4 4.3 2.7 3.0 7.1 6.6 3.9 0.6 6.8 7.5 4.5 5.2 5.9 6.9 3.6 6.1 3.8 4.4 6.1 5.4 2.8 3.9 4.2 4.0 5.3 8.2 5.0 3.0 4.0 3.7 7.2 6.2 4.9 4.8 5.1 3.7 6.5 8.1 3.1 6.0 7.1 4.9 14.3 7.6 6.7 3.3 17.6 11.9 2.3 3.9 5.5 3.3 3.1 3.9 5.2 13.4 17.6 4.1 3.3 10.5 11.4 2.8 3.5 4.7 6.1 5.9 4.6 3.7 5.9 7.7 3.8 5.3 6.0 4.7 5.1 4.2 7.7 7.9 7.5 5.3 3.7 4.6 13.1 58.8 10.5 4.3 6.7 5.4 2.6 1.8 6.3 3.8 2.4 4.0 2.6 3.2 3.0 1.6 2.7 3.1 3.7 25.7 3.1 2.7 1.1 2.4 1.9 4.7 5.2 15.9 8.1 6.5 3.1 3.3 3.2 3.3 0.6 5.2 6.1 21.5 28.9 23.9 45.1 29.3 52.6 10.7 17.0 23.3 52.9 16.3 9.4 17.2 27.1 20.4 20.2 164.7 16.6 38.3 59.1 17.6 10.6 9.1 12.7 16.4 22.7 37.1 23.1 113.4 10.5 10.1 15.9 24.5 16.2 24.7 19.9 35.3 21.0 12.0 26.9 98.3 23.4 22.4 33.9 51.6 6.6 31.7 21.1 30.2 45.0 41.5 20.3 73.2 57.8 64.6 21.3 31.1 25.6 34.0 13.2 47.3 16.4 23.1 42.7 19.7 14.8 15.9 32.8 22.9 31.6 74.2 17.4 35.6 15.3 22.0 19.6 FAM13A "ARHGAP48, FAM13A1, KIAA0914" ENSG00000138640 "Family with sequence similarity 13 member A" O94988 4 88725955-89111398 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 178.0;Oligodendrocyte precursor cells: 157.8;Syncytiotrophoblasts: 279.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 55.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038108, HPA038109" Uncertain Approved "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Cytosol" Nucleoli "HPA038108: AB_2675837, HPA038109: AB_10672619" "unprognostic (1.14e-1)" "unprognostic (1.53e-2)" "unprognostic (6.29e-2)" "unprognostic (2.53e-1)" "unprognostic (3.20e-1)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.81e-1)" "unprognostic (8.20e-2)" "unprognostic (1.75e-1)" "unprognostic (1.46e-3)" "unprognostic (6.36e-2)" "unprognostic (4.71e-1)" "unprognostic (3.49e-3)" "unprognostic (1.90e-2)" "unprognostic (7.44e-2)" "prognostic favorable (4.28e-4)" 49.2 12.8 8.5 9.9 9.0 12.7 31.8 14.2 11.8 17.6 13.2 18.3 50.5 12.5 7.5 7.6 23.5 16.3 9.9 9.7 7.3 21.9 39.1 11.8 6.3 8.6 8.4 27.8 38.6 49.2 8.4 35.1 9.5 10.6 14.8 15.9 23.4 10.5 9.7 20.4 29.0 13.3 8.3 5.4 16.3 13.9 9.0 5.6 32.8 21.9 4.8 16.9 10.4 8.8 4.5 6.7 9.8 12.8 55.5 22.7 16.0 10.2 12.4 4.0 3.6 5.6 10.3 0.1 4.0 7.4 6.3 2.7 14.5 7.4 8.9 0.6 10.0 7.5 8.9 0.7 16.3 6.3 1.0 21.9 5.9 10.1 3.6 17.5 6.9 2.5 19.7 0.7 8.7 0.2 0.7 2.8 12.1 0.8 6.9 10.2 16.6 4.0 7.4 21.8 24.6 6.5 2.5 7.9 9.9 9.6 5.5 0.2 2.5 11.2 6.2 5.5 5.9 3.4 2.1 0.1 16.6 0.6 5.9 0.0 4.1 0.0 1.0 2.0 0.7 0.0 2.7 0.3 3.5 0.0 2.9 0.7 0.9 0.4 0.6 1.2 1.5 1.6 8.5 9.0 14.2 11.8 9.7 7.3 8.6 8.4 9.5 8.3 9.0 8.8 42.6 12.8 34.9 95.3 4.3 10.1 22.3 20.4 28.5 16.3 29.7 20.6 25.9 38.6 39.3 11.0 35.5 72.9 12.9 50.4 29.4 10.7 3.4 82.0 33.6 14.1 4.9 31.3 178.0 16.9 35.3 42.1 33.1 98.2 1.3 70.2 12.8 143.0 20.7 0.0 46.5 54.1 26.4 29.6 11.9 5.1 45.1 21.7 19.6 104.9 16.9 22.6 5.2 157.8 17.4 20.7 73.4 33.4 10.3 13.6 37.5 50.4 74.6 11.3 0.0 24.7 31.9 5.3 10.2 14.4 7.7 279.5 9.7 41.2 22.3 19.5 FAM161B "C14orf44, FLJ31697" ENSG00000156050 "FAM161 centrosomal protein B" Q96MY7 14 73931501-73950414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 62.9;Late spermatids: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019125 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 21: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA019125: AB_1845570" "unprognostic (1.50e-1)" "unprognostic (9.03e-2)" "unprognostic (6.35e-2)" "unprognostic (1.99e-1)" "unprognostic (9.51e-2)" "unprognostic (1.79e-2)" "unprognostic (1.76e-3)" "unprognostic (5.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.57e-1)" "unprognostic (7.83e-2)" "unprognostic (1.53e-1)" "prognostic favorable (6.78e-4)" "unprognostic (1.26e-1)" "unprognostic (1.37e-1)" "unprognostic (7.35e-2)" "unprognostic (1.60e-1)" 2.7 8.7 6.6 1.7 6.6 1.2 4.8 5.8 8.2 5.3 3.4 3.9 3.3 5.2 4.3 4.1 5.5 2.7 5.4 6.4 5.9 7.2 5.1 2.8 1.8 6.8 5.7 12.8 2.2 4.3 7.6 2.4 7.1 6.0 2.7 10.1 2.8 5.2 7.9 2.1 3.3 3.4 5.5 3.1 3.3 18.8 6.1 1.9 4.2 4.8 1.8 5.5 3.8 6.6 2.1 1.6 2.2 3.4 4.7 3.5 2.0 3.6 2.8 6.0 5.8 1.5 2.6 3.3 2.3 4.2 2.5 3.9 0.9 1.7 4.1 9.2 1.8 1.6 1.6 1.7 4.0 1.1 2.3 2.6 3.4 6.1 2.2 4.4 2.7 3.4 1.0 1.6 4.3 3.3 3.1 4.2 0.5 1.4 3.5 2.1 2.9 1.3 3.1 3.1 2.7 2.5 5.1 2.3 3.1 1.6 8.1 1.5 2.9 12.4 5.6 3.1 2.2 3.3 2.2 2.1 6.3 1.9 2.2 3.2 1.3 1.9 1.1 0.3 1.3 0.7 1.2 1.7 0.2 0.9 0.6 0.4 0.4 1.3 0.4 0.3 0.7 0.9 6.6 6.6 5.8 8.2 6.4 5.9 6.8 5.7 7.1 5.5 6.1 6.6 3.5 3.2 4.8 4.9 3.0 0.6 2.1 1.0 3.4 8.9 3.7 3.8 3.4 0.0 3.2 1.8 4.2 1.5 1.9 3.5 0.0 1.0 62.9 5.9 3.9 2.2 0.0 1.7 7.3 1.6 1.1 4.6 7.1 4.5 0.0 5.0 2.5 0.7 2.9 3.3 8.6 4.1 2.0 1.2 0.7 142.7 3.4 1.4 1.8 2.8 2.2 8.0 6.2 5.5 2.9 1.2 0.8 9.4 1.4 0.8 4.3 4.2 9.4 16.7 6.6 5.2 4.2 11.0 6.1 0.6 0.9 2.2 3.3 9.6 1.4 0.9 FAM163B C9orf166 ENSG00000196990 "Family with sequence similarity 163 member B" P0C2L3 9 133577081-133609389 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 60.1" "Group enriched" "Detected in some" 6 "Excitatory neurons: 24.8;Inhibitory neurons: 17.8;Late spermatids: 17.3" "Cancer enriched" "Detected in some" 6 "glioma: 3.2" "Group enriched" "Detected in many" 6 "amygdala: 26.5;basal ganglia: 44.4;cerebral cortex: 60.1;hippocampal formation: 38.2;white matter: 32.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 20 "SH-SY5Y: 50.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA067336 Enhanced Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear bodies, Plasma membrane, Cytosol" "HPA067336: AB_2685825" "unprognostic (2.94e-2)" "unprognostic (6.87e-3)" "unprognostic (2.65e-2)" "unprognostic (2.70e-1)" "unprognostic (1.23e-2)" "unprognostic (9.05e-2)" "unprognostic (1.02e-2)" "unprognostic (3.48e-2)" "unprognostic (1.43e-1)" "unprognostic (1.16e-1)" "unprognostic (3.31e-3)" "unprognostic (7.61e-2)" "unprognostic (5.75e-4)" "unprognostic (1.07e-1)" "unprognostic (9.54e-2)" "unprognostic (1.65e-1)" "unprognostic (4.73e-4)" 0.1 10.0 26.5 0.0 44.4 0.0 0.0 0.0 60.1 0.0 0.0 0.8 0.0 0.0 0.3 0.0 0.1 0.4 5.2 38.2 0.0 0.8 8.7 0.3 1.7 0.0 0.0 0.4 0.1 0.0 0.5 0.8 7.3 0.2 0.5 0.2 0.3 0.8 0.0 0.0 0.0 0.0 6.0 0.2 0.4 2.4 0.0 0.2 0.2 0.0 0.0 1.1 0.1 32.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.7 0.2 0.1 0.0 0.0 2.4 50.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 44.4 0.0 60.1 38.2 0.0 0.0 0.0 7.3 6.0 0.0 32.5 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 24.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 2.8 0.0 0.0 0.0 2.5 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 263.8;Cholangiocytes: 98.7;Excitatory neurons: 166.9;Oligodendrocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "TIME: 105.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA051345: AB_2681449" "unprognostic (3.60e-2)" "unprognostic (7.15e-2)" "unprognostic (2.21e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (4.11e-2)" "unprognostic (9.84e-2)" "unprognostic (9.19e-2)" "unprognostic (2.28e-1)" "unprognostic (3.97e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.71e-5)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (4.90e-6)" "unprognostic (3.28e-2)" 11.0 5.0 60.1 7.5 73.2 0.5 8.8 69.8 56.4 11.8 22.7 21.6 19.1 12.8 6.4 6.4 15.6 12.9 10.6 68.5 49.5 31.9 15.4 7.4 6.0 79.6 64.8 14.2 22.4 10.9 3.7 4.1 75.6 11.2 17.6 2.6 14.1 11.9 7.6 4.2 13.0 12.3 59.3 12.4 13.3 3.5 68.7 3.9 6.9 6.1 6.6 9.0 6.3 86.7 0.0 16.2 33.3 12.6 13.2 24.9 0.4 19.5 3.9 10.2 8.8 3.0 19.2 0.1 21.5 53.4 22.7 1.4 24.0 0.2 11.5 5.9 33.4 46.7 5.2 48.1 14.3 0.0 36.0 19.7 4.9 27.8 4.0 36.8 51.4 6.8 17.5 0.2 32.8 1.4 7.7 0.1 30.4 9.3 7.8 30.4 17.0 5.1 12.7 0.0 22.4 27.6 10.9 0.2 0.1 35.0 0.2 0.6 105.6 13.9 53.6 50.4 20.8 6.3 2.1 0.1 30.3 0.0 10.8 0.0 0.0 0.0 1.7 0.0 4.4 0.0 2.5 2.2 0.0 0.0 4.7 2.4 0.0 0.2 0.0 0.0 0.5 0.9 60.1 73.2 69.8 56.4 68.5 49.5 79.6 64.8 75.6 59.3 68.7 86.7 11.1 0.0 0.0 263.8 1.0 1.3 4.0 3.1 8.0 4.0 7.6 5.7 6.8 98.7 1.7 14.7 0.0 0.1 0.2 25.4 3.9 21.1 0.7 5.9 12.5 43.7 21.0 6.5 166.9 12.2 0.2 12.3 35.7 14.6 1.3 14.4 49.2 24.7 0.4 6.7 76.6 23.7 4.1 2.8 1.7 1.1 5.3 0.3 1.8 33.7 0.7 1.5 0.0 44.2 214.4 17.5 16.1 5.7 5.2 16.5 7.3 4.5 2.4 1.1 0.0 7.5 5.9 2.3 5.7 8.0 1.8 0.1 2.0 11.4 38.8 3.6 FAM186A LOC121006 ENSG00000185958 "Family with sequence similarity 186 member A" A6NE01 12 50326230-50396622 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "testis: 14.2" "Cell type enriched" "Detected in some" 8 "Early spermatids: 521.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047128, HPA064735" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA047128: AB_10967726, HPA064735: " "unprognostic (1.01e-1)" "unprognostic (1.29e-1)" "unprognostic (1.25e-1)" "unprognostic (2.31e-1)" "unprognostic (1.88e-1)" "unprognostic (3.69e-2)" "unprognostic (3.48e-3)" "unprognostic (1.43e-2)" "unprognostic (1.30e-2)" "unprognostic (6.96e-2)" "unprognostic (4.65e-5)" "unprognostic (1.93e-1)" "unprognostic (2.42e-5)" "unprognostic (1.65e-1)" "unprognostic (1.32e-1)" "unprognostic (7.51e-2)" "unprognostic (3.22e-3)" 0.1 0.3 0.2 0.2 0.4 0.5 0.1 0.6 0.4 0.2 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.2 0.1 0.6 0.3 0.1 0.2 0.1 0.0 0.2 0.3 0.0 0.9 0.0 0.1 0.3 0.1 0.7 0.2 0.0 1.1 0.3 0.2 0.0 0.0 0.3 0.1 14.2 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.3 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.6 0.3 0.1 0.1 0.0 0.0 0.2 0.4 0.6 0.4 0.2 0.1 0.1 0.0 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 521.1 0.1 0.2 0.1 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 64.7 0.6 0.1 0.0 2.8 0.0 0.6 0.0 1.5 3.2 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 1.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM193A "C4orf8, RES4-22" ENSG00000125386 "Family with sequence similarity 193 member A" P78312 4 2536647-2732573 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043116 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA043116: AB_10795767" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (1.17e-3)" "unprognostic (1.97e-1)" "unprognostic (3.66e-3)" "unprognostic (6.34e-3)" "unprognostic (1.02e-1)" "unprognostic (7.16e-2)" "unprognostic (4.84e-1)" "prognostic favorable (4.80e-4)" "unprognostic (1.38e-2)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (3.47e-2)" "unprognostic (5.55e-2)" "unprognostic (4.96e-3)" 14.3 11.7 9.7 7.6 9.3 13.0 13.2 15.1 11.5 14.8 9.6 13.4 7.9 13.8 6.8 9.6 12.9 6.0 9.7 9.5 9.7 11.9 11.6 10.1 9.6 9.8 9.0 15.0 11.1 9.2 15.5 7.6 9.3 12.1 6.0 8.9 10.1 7.0 15.1 13.2 12.3 8.0 6.9 12.0 10.5 21.1 10.5 12.4 12.2 8.7 6.7 11.5 11.2 11.8 8.7 10.7 20.0 11.3 12.0 12.2 10.5 13.1 11.3 12.7 10.8 10.9 13.9 17.1 7.7 14.7 15.7 7.4 14.0 9.4 10.8 10.3 8.9 25.7 14.3 11.5 14.4 15.8 17.2 13.3 9.8 12.7 13.0 11.6 12.8 10.0 18.2 18.5 10.8 9.4 25.5 25.6 15.9 8.9 11.8 24.7 10.3 8.4 8.7 11.1 17.1 14.6 11.2 7.8 11.3 10.9 14.3 15.9 17.4 19.2 11.3 10.5 17.5 18.0 14.5 16.1 10.7 12.8 13.8 3.3 0.9 0.8 0.8 0.6 0.6 0.6 0.7 1.2 0.6 0.9 0.7 1.1 1.8 1.3 3.1 1.7 0.6 0.5 9.7 9.3 15.1 11.5 9.5 9.7 9.8 9.0 9.3 6.9 10.5 11.8 21.8 12.8 18.2 62.7 11.2 9.4 6.7 6.5 9.1 25.7 10.5 9.0 14.7 4.3 15.6 1.8 47.9 7.3 20.0 12.9 1.9 9.4 8.9 19.8 21.8 19.4 14.4 17.9 62.4 7.5 7.1 13.2 15.8 27.1 8.8 30.2 11.0 6.3 8.7 15.2 70.8 11.1 8.2 7.6 11.6 13.4 17.1 15.9 14.2 51.5 11.1 15.8 11.3 45.8 58.3 10.1 11.0 14.7 12.4 11.3 11.4 2.8 5.6 26.2 6.6 20.5 17.5 36.2 32.4 9.6 9.9 5.6 14.4 13.6 9.6 9.2 FAM205A C9orf144B ENSG00000205108 "Family with sequence similarity 205 member A" Q6ZU69 9 34723053-34729488 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 96 "testis: 24.8" "Cell type enriched" "Detected in some" 5 "Early spermatids: 135.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071267 Enhanced Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "Nucleoli fibrillar center" "HPA071267: AB_2686376" "unprognostic (2.25e-1)" "unprognostic (3.66e-3)" "unprognostic (6.29e-3)" "unprognostic (1.90e-1)" "unprognostic (2.73e-3)" "unprognostic (7.82e-2)" "unprognostic (9.61e-2)" "unprognostic (6.41e-2)" "unprognostic (4.78e-1)" "unprognostic (7.34e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 135.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM209A "C20orf106, dJ1153D9.3" ENSG00000124103 "Family with sequence similarity 209 member A" Q5JX71 20 56517187-56526152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 104.2" "Cell type enriched" "Detected in some" 8 "Early spermatids: 2173.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.5;Karpas-707: 1.0;U-266/84: 1.5" HPA079442 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA079442: " "unprognostic (1.03e-1)" "unprognostic (1.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (8.58e-3)" "unprognostic (1.06e-2)" "unprognostic (2.12e-1)" "unprognostic (2.10e-1)" "unprognostic (9.83e-2)" "unprognostic (5.56e-3)" "unprognostic (7.68e-2)" "unprognostic (1.86e-9)" "unprognostic (2.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-2)" 0.6 0.2 0.1 0.9 0.1 16.6 0.5 0.1 0.3 0.4 0.0 0.5 0.3 0.3 0.4 0.3 0.4 0.5 0.2 0.1 0.1 0.3 0.6 0.8 1.5 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.1 0.6 0.4 0.1 0.5 0.3 0.2 1.2 1.1 0.2 0.0 2.3 0.5 104.2 0.1 0.2 0.3 0.0 1.3 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.3 0.0 0.3 0.0 0.4 2.5 0.0 0.7 0.0 0.1 0.1 0.1 0.5 0.0 1.0 0.0 0.4 0.1 0.7 0.0 0.0 0.1 0.2 0.3 0.2 0.0 0.4 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.5 0.0 0.0 0.1 0.2 0.1 0.5 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 2.3 0.0 0.4 0.1 0.2 0.1 0.0 0.0 0.2 0.3 0.7 0.0 0.7 0.0 0.0 0.1 2.0 0.4 0.0 0.0 2173.4 0.2 0.2 1.1 1.2 0.4 0.0 0.0 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 266.1 8.7 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 6.4 0.0 0.1 0.2 0.0 0.8 0.0 0.0 0.3 0.2 10.4 5.9 0.1 0.0 0.3 0.5 0.1 0.1 0.2 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM222A "C12orf34, FLJ14721" ENSG00000139438 "Family with sequence similarity 222 member A" Q5U5X8 12 109713825-109770495 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.6" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 33.3;Early spermatids: 29.1;Horizontal cells: 77.4;Oligodendrocytes: 78.5;Rod photoreceptor cells: 50.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040181, HPA075616" Uncertain Approved "Golgi apparatus,Cell Junctions,Midbody ring" Yes NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 46: Photoreceptor cells - Phototransduction" "Golgi apparatus" "Cell Junctions, Midbody ring" "HPA040181: AB_10796448, HPA075616: " "unprognostic (8.59e-3)" "prognostic favorable (1.82e-5)" "unprognostic (1.43e-1)" "unprognostic (1.57e-1)" "unprognostic (1.92e-1)" "unprognostic (2.05e-2)" "unprognostic (1.46e-2)" "unprognostic (1.03e-1)" "unprognostic (6.66e-2)" "unprognostic (8.17e-2)" "prognostic favorable (4.81e-4)" "unprognostic (1.15e-1)" "unprognostic (4.16e-2)" "prognostic favorable (8.59e-4)" "unprognostic (3.93e-2)" "unprognostic (2.77e-1)" "unprognostic (1.24e-1)" 0.7 19.0 23.7 0.7 45.2 0.6 1.2 36.7 34.2 0.6 5.6 1.9 4.8 0.3 0.8 2.3 0.4 0.8 8.9 20.0 27.6 10.6 4.0 2.1 0.4 41.2 43.1 13.4 3.9 0.7 22.4 0.1 37.7 1.8 1.0 22.1 3.4 0.5 4.3 3.2 2.2 0.4 29.0 6.2 7.2 23.4 48.4 0.4 0.7 0.6 0.6 0.9 1.8 65.6 2.0 3.1 1.6 3.7 1.0 0.0 1.1 0.6 0.3 1.6 0.2 28.1 0.5 0.3 2.2 0.8 1.7 1.2 1.9 0.1 0.6 16.8 4.0 3.5 0.9 6.5 0.2 2.8 3.6 0.2 0.2 0.3 0.0 0.4 0.1 2.0 1.2 0.6 0.3 11.5 0.7 3.6 3.0 3.3 5.3 2.3 8.0 1.2 3.5 1.5 19.2 116.4 2.5 3.7 8.2 0.5 4.5 3.0 0.2 0.5 3.2 1.3 2.4 2.9 4.0 2.4 0.3 2.1 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.7 45.2 36.7 34.2 20.0 27.6 41.2 43.1 37.7 29.0 48.4 65.6 2.1 0.0 0.0 2.3 3.6 2.2 0.9 0.1 3.4 23.4 7.4 6.1 8.1 1.5 0.8 1.8 33.3 0.3 10.4 1.2 7.9 1.7 29.1 1.2 0.5 1.3 7.7 0.0 1.3 0.8 0.2 1.5 1.5 1.8 0.0 0.7 0.7 1.3 0.3 77.4 6.7 5.8 0.0 0.0 2.1 13.4 1.2 1.9 7.2 0.0 0.1 11.2 0.0 9.5 78.5 1.1 0.2 0.4 1.3 1.7 0.9 0.7 0.6 50.3 0.0 2.6 1.5 1.1 5.7 3.3 1.8 0.8 3.7 6.0 1.6 0.4 FAM47E "FLJ42946, LOC100129583" ENSG00000189157 "Family with sequence similarity 47 member E" Q6ZV65 4 76214040-76283783 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 47.3;Endometrial ciliated cells: 34.0;Respiratory ciliated cells: 91.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 5 "OE19: 28.0" HPA053331 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-4)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-8)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-2)" "unprognostic (3.01e-2)" 6.2 4.9 7.6 0.4 8.3 1.0 6.8 7.5 8.8 2.9 7.9 2.6 3.2 1.7 11.0 1.3 19.6 4.0 1.9 8.0 8.4 7.3 9.1 4.0 0.5 8.1 8.5 0.8 9.1 7.6 8.5 1.5 7.8 4.2 2.9 8.8 4.4 2.7 6.4 1.3 3.5 1.1 7.8 1.2 5.1 8.0 9.5 0.7 9.7 3.2 0.4 1.9 0.7 9.1 0.6 2.1 2.1 0.6 1.6 0.2 0.5 0.2 2.0 0.4 0.4 2.6 2.2 0.1 0.6 0.7 4.5 0.6 0.9 0.5 0.7 2.1 0.1 0.1 1.3 3.6 0.9 0.5 0.3 1.0 0.5 0.6 0.5 0.9 0.2 0.3 0.2 1.5 0.6 3.1 0.2 0.2 0.4 28.0 1.0 0.3 0.5 0.3 3.4 1.8 3.7 2.9 1.0 1.6 0.3 0.5 1.7 0.2 0.5 0.4 0.5 1.2 0.5 5.5 1.2 0.1 1.6 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 7.6 8.3 7.5 8.8 8.0 8.4 8.1 8.5 7.8 7.8 9.5 9.1 1.6 9.6 2.6 4.2 0.4 0.6 2.5 5.1 0.0 12.9 7.7 9.1 7.9 8.6 8.4 0.0 12.5 3.3 0.1 6.2 9.8 7.5 47.3 34.0 0.6 1.8 7.7 0.8 1.0 7.8 1.6 1.5 3.1 2.0 0.0 1.5 1.8 3.6 0.8 1.7 1.1 5.7 14.2 1.0 0.0 6.2 0.6 0.7 1.8 1.0 0.0 4.7 0.0 0.0 2.9 5.8 3.0 0.4 0.4 2.8 13.0 10.3 91.4 7.4 0.0 2.0 2.2 8.8 4.3 0.3 0.3 3.4 0.2 0.8 3.1 1.9 FAM47E-STBD1 ENSG00000272414 "FAM47E-STBD1 readthrough" 4 76251721-76311129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 41.5;skeletal muscle: 55.9" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 1.7;Astrocytes: 2.0;Excitatory neurons: 5.1;Inhibitory neurons: 2.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 3.4;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;OE19: 2.7" HPA053331 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (3.52e-3)" "unprognostic (3.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.98e-2)" "unprognostic (5.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.51e-2)" "unprognostic (1.91e-1)" "unprognostic (6.92e-6)" "unprognostic (5.59e-2)" "unprognostic (1.52e-1)" "unprognostic (3.77e-1)" 12.5 1.3 1.5 0.4 1.6 1.0 9.3 1.1 2.5 2.0 1.1 9.0 0.1 2.4 1.3 1.6 2.1 0.6 21.2 1.4 2.0 2.4 41.5 8.3 0.4 1.9 1.5 0.9 2.3 0.5 0.7 0.6 1.7 4.3 0.4 1.8 2.3 0.5 55.9 0.9 12.4 0.7 1.6 0.9 2.9 2.3 1.9 0.1 1.3 0.5 0.1 6.7 2.0 2.0 0.1 0.0 0.1 0.1 0.4 0.1 0.2 0.0 0.2 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.6 0.1 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 0.0 0.4 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.1 0.1 2.7 0.4 0.0 0.0 0.4 0.0 0.6 0.7 0.5 0.1 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.3 0.1 0.2 0.4 0.3 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 1.5 1.6 1.1 2.5 1.4 2.0 1.9 1.5 1.7 1.6 1.9 2.0 0.0 6.4 1.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM72A "LMPIP, MGC57827, p17, RP11-312O7.1, UGENE" ENSG00000196550 "Family with sequence similarity 72 member A" Q5TYM5 1 206186179-206204414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 10.9" "Cell type enhanced" "Detected in many" "Early spermatids: 29.5;Kupffer cells: 18.2;Late spermatids: 30.2;Spermatocytes: 28.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 7: Monocytes - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (3.61e-2)" "unprognostic (1.58e-1)" "unprognostic (1.80e-1)" "unprognostic (5.20e-5)" "unprognostic (3.61e-1)" "unprognostic (1.19e-3)" "unprognostic (1.01e-5)" "unprognostic (7.70e-3)" "unprognostic (1.45e-2)" "unprognostic (5.58e-3)" "unprognostic (2.87e-2)" "unprognostic (1.03e-1)" "unprognostic (4.44e-16)" "unprognostic (1.82e-1)" "unprognostic (1.94e-2)" "unprognostic (4.83e-2)" "unprognostic (3.89e-1)" 4.0 3.1 2.6 5.9 2.9 8.4 3.6 9.1 3.1 1.3 1.0 2.2 3.1 0.9 0.4 2.5 1.8 2.7 1.2 3.1 4.0 1.3 2.0 2.6 10.9 5.4 4.4 1.1 1.4 1.6 0.8 3.5 5.8 1.1 2.3 0.2 1.0 0.7 0.6 5.9 2.9 2.0 4.1 6.3 1.5 7.1 4.8 8.6 0.9 1.0 7.5 1.5 1.5 4.7 21.1 16.4 17.7 7.7 2.6 3.1 21.1 14.6 6.3 17.1 12.7 9.9 31.1 54.2 12.3 3.8 18.8 24.7 20.9 8.1 20.2 29.5 16.3 24.3 16.4 13.9 1.8 42.9 27.0 4.4 1.4 15.1 26.7 5.1 10.7 45.7 50.1 36.7 10.7 12.9 26.9 38.3 32.1 15.1 22.1 29.5 30.6 41.4 9.8 3.2 17.7 10.2 10.6 9.7 9.3 20.1 20.5 23.2 5.5 13.5 15.5 17.7 24.9 29.1 44.8 48.4 11.1 34.9 18.8 0.0 5.9 0.0 0.7 8.0 0.2 1.7 1.4 1.4 4.6 0.5 0.1 0.3 1.0 0.6 4.8 1.9 2.9 2.1 2.6 2.9 9.1 3.1 3.1 4.0 5.4 4.4 5.8 4.1 4.8 4.7 5.9 0.0 1.5 0.0 2.4 1.8 0.4 1.2 1.2 0.3 0.8 0.6 1.5 0.0 0.9 0.0 0.0 0.8 3.7 4.9 0.0 1.0 29.5 1.5 1.5 8.4 0.0 0.4 0.1 0.8 3.8 1.8 0.5 0.7 0.0 0.3 7.1 0.4 9.4 0.0 0.2 3.6 0.0 18.2 5.8 30.2 0.0 6.9 3.6 0.0 9.6 0.6 2.1 0.0 0.1 0.6 0.0 0.0 1.6 0.4 1.3 0.3 2.1 0.2 0.0 0.9 2.2 28.0 4.1 2.0 1.0 0.7 1.4 0.8 1.6 0.8 FAM72B RP11-439A17.6 ENSG00000188610 "Family with sequence similarity 72 member B" Q86X60 1 121167646-121185539 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 6.2;lymphoid tissue: 10.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 7.3;Early spermatids: 11.3;Erythroid cells: 5.9;Hepatic stellate cells: 6.4;Spermatocytes: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 28: Myeloid DCs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (8.53e-2)" "unprognostic (1.97e-2)" "unprognostic (1.63e-3)" "unprognostic (1.25e-3)" "unprognostic (4.36e-1)" "unprognostic (1.05e-1)" "unprognostic (1.26e-4)" "unprognostic (8.22e-5)" "unprognostic (1.30e-2)" "unprognostic (1.79e-2)" "unprognostic (1.36e-4)" "unprognostic (2.46e-2)" "unprognostic (0.00e+0)" "unprognostic (2.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-2)" "unprognostic (5.30e-2)" 0.8 0.6 1.2 3.7 1.0 6.2 0.8 2.0 1.1 0.5 1.3 1.1 1.3 0.5 0.4 1.6 0.4 1.0 0.3 1.2 1.2 0.4 0.4 0.6 8.1 1.6 1.4 0.4 0.2 0.7 0.2 1.4 1.6 0.2 1.2 0.1 0.4 0.2 0.1 1.9 1.1 0.7 1.3 2.0 1.0 2.3 1.3 10.3 0.3 0.2 6.6 0.8 0.7 1.4 28.6 10.3 16.5 8.2 1.6 2.4 13.3 14.7 6.2 16.8 14.1 0.1 14.5 62.9 19.9 2.7 16.4 17.1 23.1 8.3 25.9 41.1 17.3 27.2 12.0 12.5 1.0 47.7 23.2 1.3 0.9 13.0 26.5 4.2 10.3 51.0 36.1 37.3 12.4 12.1 24.1 39.1 31.6 14.9 20.6 35.8 35.8 28.7 6.7 3.2 18.0 10.4 11.1 8.6 8.6 16.9 11.4 36.5 3.6 13.8 23.5 27.3 26.6 32.6 44.1 61.3 12.4 50.8 32.6 0.0 0.6 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.1 0.4 0.3 1.2 1.0 2.0 1.1 1.2 1.2 1.6 1.4 1.6 1.3 1.3 1.4 1.3 0.0 0.0 0.0 1.6 1.0 0.1 0.2 0.0 0.0 0.3 0.6 0.4 0.0 0.1 0.0 0.0 0.8 0.1 7.3 0.0 0.2 11.3 0.2 0.4 2.5 0.0 5.9 0.1 0.2 2.3 0.6 1.1 0.2 0.0 0.5 6.4 0.0 1.1 0.0 0.3 4.9 0.0 1.9 2.8 3.0 0.6 1.6 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.1 2.3 0.0 2.5 0.0 2.1 0.0 0.7 0.0 0.0 0.3 0.9 17.0 3.1 3.5 1.0 0.1 1.2 0.2 3.6 0.0 FAM72C RP5-998N21.9 ENSG00000263513 "Family with sequence similarity 72 member C" H0Y354 1 143955364-143971965 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 2.9;lymphoid tissue: 5.4" "Cell type enhanced" "Detected in some" "Erythroid cells: 7.8;Extravillous trophoblasts: 4.5;Sertoli cells: 6.6;Spermatocytes: 9.4;Spermatogonia: 3.5" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/84: 64.9" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" "unprognostic (6.45e-3)" "unprognostic (2.69e-2)" "unprognostic (2.21e-1)" "unprognostic (3.98e-3)" "unprognostic (9.46e-5)" "unprognostic (1.23e-3)" "unprognostic (4.36e-1)" "unprognostic (7.26e-2)" "unprognostic (1.04e-2)" "unprognostic (1.95e-1)" "unprognostic (0.00e+0)" "unprognostic (2.95e-1)" "unprognostic (4.70e-2)" "unprognostic (5.82e-2)" "unprognostic (1.47e-2)" 0.4 0.2 0.1 1.5 0.1 2.9 0.3 0.2 0.2 0.2 0.0 0.4 0.6 0.2 0.0 1.3 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.3 4.5 0.1 0.1 0.1 0.2 0.0 0.0 0.5 0.1 0.1 0.6 0.0 0.2 0.0 0.0 1.2 0.4 0.3 0.1 1.2 0.3 1.6 0.1 5.4 0.1 0.1 4.5 0.4 0.4 0.2 18.7 10.6 12.5 5.7 0.6 1.7 12.1 8.9 2.8 12.0 9.0 1.6 21.7 44.4 11.6 1.0 11.0 17.4 17.2 5.5 13.0 15.3 10.0 19.1 9.4 3.3 0.4 39.5 16.6 0.3 0.1 9.1 24.3 2.5 5.1 34.7 34.0 20.5 0.8 1.4 23.2 30.4 10.2 20.8 6.6 29.7 9.0 31.5 2.1 2.3 6.3 11.5 8.7 5.0 4.9 13.0 12.5 33.4 3.7 9.4 15.4 12.5 20.3 41.9 64.9 26.0 5.1 24.1 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.4 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.8 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.6 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 2.1 0.0 0.1 0.0 0.0 2.3 0.3 0.2 1.3 0.0 7.8 0.2 0.2 4.5 0.3 0.0 0.1 0.0 0.5 1.8 0.1 1.7 0.0 0.3 0.6 0.0 2.2 1.4 0.5 0.3 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 6.6 0.3 0.7 9.4 3.5 1.3 0.3 0.3 0.7 0.3 0.5 0.0 FAM72D ENSG00000215784 "Family with sequence similarity 72 member D" Q6L9T8 1 145095974-145112696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;lymphoid tissue: 6.7" "Group enriched" "Detected in some" 4 "Early spermatids: 7.3;Erythroid cells: 9.7;Extravillous trophoblasts: 5.5;Spermatocytes: 15.4;Spermatogonia: 4.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "HPA043271, HPA067321" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane, Cytosol" "HPA043271: AB_2678402, HPA067321: " "unprognostic (2.70e-2)" "unprognostic (1.64e-1)" "unprognostic (1.73e-1)" "unprognostic (4.03e-3)" "unprognostic (1.26e-1)" "unprognostic (7.10e-3)" "unprognostic (5.88e-5)" "unprognostic (7.65e-4)" "unprognostic (6.72e-2)" "unprognostic (2.36e-2)" "unprognostic (1.22e-2)" "unprognostic (1.46e-1)" "unprognostic (0.00e+0)" "unprognostic (6.63e-2)" "unprognostic (1.72e-1)" "unprognostic (9.74e-2)" "unprognostic (6.50e-2)" 0.7 0.3 0.4 3.0 0.4 4.0 0.5 0.7 0.5 0.3 0.2 0.8 1.0 0.3 0.1 1.1 0.2 0.5 0.2 0.4 0.8 0.2 0.3 0.5 4.8 0.6 0.7 0.2 0.1 0.2 0.1 1.1 0.6 0.1 1.0 0.1 0.2 0.1 0.0 1.9 1.3 0.5 0.4 1.2 0.6 2.1 0.7 6.7 0.2 0.1 4.5 0.6 0.4 0.5 16.6 10.4 11.7 4.5 0.5 1.0 12.4 9.8 3.0 11.1 7.1 7.5 14.7 26.6 9.3 1.5 11.1 17.3 13.6 3.0 12.8 22.6 14.1 13.6 5.8 9.7 0.6 24.0 14.2 0.8 1.1 9.4 16.9 2.0 5.6 33.0 26.8 34.9 7.2 12.4 16.6 22.5 21.1 20.3 14.4 13.9 14.3 30.7 4.0 2.2 10.9 9.1 7.3 6.3 4.4 13.9 17.2 15.7 2.7 8.3 9.6 7.3 16.7 27.0 46.5 39.3 0.2 18.7 10.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.4 0.4 0.7 0.5 0.4 0.8 0.6 0.7 0.6 0.4 0.7 0.5 2.0 0.0 0.0 0.0 0.8 1.0 0.0 0.2 1.2 0.0 0.2 0.4 1.1 0.0 0.2 0.0 0.0 1.2 0.1 0.8 0.0 0.1 7.3 0.2 0.3 2.1 0.0 9.7 0.3 0.0 5.5 0.8 0.0 0.2 0.0 0.3 0.4 0.1 1.5 0.0 0.5 0.8 0.0 1.0 1.0 0.6 0.0 1.8 1.8 1.0 0.8 0.0 0.0 1.0 0.1 0.1 0.1 0.0 0.8 0.2 0.3 0.1 0.3 0.0 0.0 0.5 0.8 15.4 4.5 1.6 1.0 0.3 0.4 0.1 1.4 0.1 FANCG "FAG, XRCC9" ENSG00000221829 "FA complementation group G" O15287 9 35073835-35079942 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Cancer-related genes, Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 20.6;Spermatogonia: 20.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008105, HPA045335" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" Nucleoli "CAB008105: AB_2231542, HPA045335: AB_2679292" "unprognostic (9.41e-2)" "unprognostic (2.62e-2)" "unprognostic (1.82e-1)" "unprognostic (1.05e-1)" "unprognostic (2.09e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (2.02e-4)" "unprognostic (8.92e-2)" "unprognostic (1.42e-2)" "unprognostic (2.27e-3)" "unprognostic (9.01e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.14e-2)" "unprognostic (1.59e-1)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" 3.4 3.1 2.8 5.1 2.8 12.4 4.5 3.6 3.8 5.1 2.1 4.3 4.9 4.2 2.3 5.9 5.8 3.3 1.9 2.7 2.7 3.9 2.9 3.3 7.7 2.8 2.7 6.2 6.3 4.7 3.0 4.5 2.7 3.9 4.0 2.4 4.3 4.1 2.3 6.5 4.6 4.5 2.5 5.5 4.1 6.4 2.7 12.2 4.0 1.7 6.9 3.5 4.6 3.4 34.7 40.7 30.4 28.3 6.4 10.2 25.0 23.6 16.3 44.9 42.5 20.1 21.2 33.4 15.8 7.7 33.1 20.5 25.3 22.0 17.6 38.7 14.8 24.5 45.5 13.2 1.8 24.5 26.9 8.1 4.1 39.5 18.2 8.0 23.8 40.7 15.7 44.3 23.5 31.5 43.2 34.5 32.5 26.4 30.1 43.8 35.2 23.1 10.9 14.6 14.4 26.1 15.7 22.3 8.3 13.4 28.4 17.2 13.4 21.0 42.8 28.3 33.1 12.4 24.0 20.6 19.2 18.5 30.1 10.5 0.7 6.7 6.1 2.2 5.3 5.6 4.8 4.6 1.9 5.4 3.6 3.8 1.1 7.8 2.0 4.2 8.2 3.1 2.8 2.8 3.6 3.8 2.7 2.7 2.8 2.7 2.7 2.5 2.7 3.4 3.2 3.2 4.6 6.8 4.9 4.5 6.1 3.9 10.2 4.7 5.9 5.0 1.5 2.8 3.3 3.7 4.2 15.0 4.1 3.0 3.9 4.9 0.4 2.3 3.8 4.4 1.8 11.6 3.0 2.3 20.6 5.1 1.5 3.6 14.0 10.3 4.2 1.1 7.7 5.0 3.3 4.1 2.0 1.3 4.7 0.6 3.4 2.3 3.6 1.0 2.8 4.0 3.1 0.5 4.1 1.9 2.4 4.1 14.1 4.4 3.5 2.3 1.3 3.1 0.0 3.0 3.9 14.7 20.7 8.5 2.6 6.6 4.9 2.8 6.7 5.2 FAS "APO-1, APT1, CD95, FAS1, TNFRSF6" ENSG00000026103 "Fas cell surface death receptor" P25445 10 88990531-89017059 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Predicted secreted proteins" Apoptosis "Calmodulin-binding, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 114.7" "Group enriched" "Detected in all" 5 "granulocytes: 114.7;T-cells: 96.2" "Cell line enhanced" "Detected in many" "HDLM-2: 83.4;Karpas-707: 109.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027444 Uncertain Supported "Nuclear bodies,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11900000 420000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Nuclear bodies, Cytosol" "HPA027444: AB_10601378" "unprognostic (6.84e-2)" "unprognostic (2.88e-3)" "unprognostic (8.38e-3)" "unprognostic (1.94e-1)" "unprognostic (2.35e-2)" "unprognostic (9.56e-2)" "unprognostic (7.00e-2)" "unprognostic (2.05e-1)" "unprognostic (3.01e-1)" "unprognostic (7.70e-2)" "unprognostic (1.26e-2)" "unprognostic (1.98e-1)" "unprognostic (1.52e-3)" "unprognostic (2.10e-1)" "unprognostic (2.32e-2)" "unprognostic (4.95e-3)" "unprognostic (1.65e-1)" 14.1 26.3 3.6 17.0 3.6 20.8 10.9 2.9 4.7 12.7 2.8 16.4 7.0 12.8 10.3 10.8 14.8 15.7 7.5 3.6 3.7 7.2 23.3 21.7 18.9 4.6 3.1 20.1 3.7 2.7 3.7 10.4 4.0 8.9 23.3 3.3 6.5 9.3 2.3 9.4 9.2 15.0 3.5 11.2 4.4 2.6 3.9 14.4 7.3 2.6 15.6 12.9 10.2 4.3 22.7 8.2 5.4 13.9 37.0 51.3 0.0 51.8 50.2 1.7 9.1 0.1 23.4 4.7 19.0 52.1 9.6 4.0 1.0 44.8 3.2 83.4 8.7 0.4 5.2 14.7 31.6 3.4 1.6 69.2 38.7 31.4 66.0 24.5 4.7 17.8 0.0 109.0 44.0 1.4 6.4 3.4 0.6 0.2 1.8 1.4 0.5 5.0 60.7 7.3 0.4 0.2 7.7 0.0 0.8 7.0 13.9 1.0 9.5 15.8 9.0 15.2 12.3 45.3 5.3 0.4 11.8 10.2 4.5 43.1 9.4 30.9 9.9 12.3 13.8 7.5 27.6 19.6 11.5 4.0 3.1 10.0 114.7 3.1 22.1 0.2 96.2 12.8 3.6 3.6 2.9 4.7 3.6 3.7 4.6 3.1 4.0 3.5 3.9 4.3 10.3 57.7 13.8 40.1 12.8 45.9 109.7 53.1 39.9 0.0 5.5 9.5 3.5 12.8 27.5 9.2 0.0 0.4 16.3 24.9 0.0 6.3 11.3 9.2 22.3 8.9 8.4 9.5 8.8 4.3 0.2 35.4 8.6 15.5 3.8 4.9 2.2 19.3 5.5 1.7 2.8 14.4 8.2 7.0 31.7 4.9 19.0 17.7 12.4 17.8 20.9 14.5 10.3 8.0 0.7 6.5 8.7 13.9 32.2 46.0 15.6 14.4 26.3 0.7 6.6 26.8 29.1 11.3 1.1 28.5 43.9 0.4 48.4 11.8 24.4 30.0 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FAT3 "CDHF15, CDHR10, KIAA1989" ENSG00000165323 "FAT atypical cadherin 3" Q8TDW7 11 92224818-92896473 "Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 19.3" "Cell type enhanced" "Detected in some" "Astrocytes: 265.8;Excitatory neurons: 512.9;Inhibitory neurons: 149.2;Oligodendrocyte precursor cells: 88.4" "Cancer enriched" "Detected in single" 6 "glioma: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.3;fHDF/TERT166: 2.2;NTERA-2: 2.5;SuSa: 2.2;U-2 OS: 2.1;U-251 MG: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026878, HPA074824" Uncertain Approved "Cell Junctions" NA NA 4700 "Cluster 65: Brain - Ion transport" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA026878: AB_1848430, HPA074824: " "unprognostic (5.00e-2)" "unprognostic (1.37e-1)" "unprognostic (8.61e-2)" "unprognostic (4.76e-6)" "unprognostic (1.27e-1)" "unprognostic (1.79e-1)" "unprognostic (1.56e-1)" "unprognostic (9.32e-2)" "unprognostic (1.08e-1)" "unprognostic (3.04e-2)" "unprognostic (1.46e-1)" "unprognostic (1.09e-1)" "unprognostic (5.79e-2)" "unprognostic (3.66e-4)" "unprognostic (8.83e-2)" "unprognostic (7.72e-2)" "unprognostic (2.25e-1)" 0.5 0.0 5.5 0.0 19.3 0.0 0.1 1.3 9.0 0.6 0.0 0.2 0.0 0.6 0.6 0.1 0.6 0.0 0.2 4.0 15.5 0.2 0.0 1.2 0.0 0.5 4.7 0.5 0.0 0.0 2.9 0.1 1.9 2.0 0.1 1.3 0.0 3.8 0.1 0.2 0.0 0.1 0.8 0.1 2.2 0.7 7.5 0.1 0.0 0.2 0.2 2.3 1.0 1.0 0.0 0.3 7.3 0.0 0.0 0.0 0.0 0.3 0.0 0.8 0.4 0.0 0.0 0.0 1.4 2.2 0.0 1.2 0.0 0.0 0.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.2 2.1 0.0 4.3 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 19.3 1.3 9.0 4.0 15.5 0.5 4.7 1.9 0.8 7.5 1.0 0.0 0.0 0.0 265.8 0.0 0.1 0.3 0.9 0.0 20.8 0.1 0.5 1.8 0.0 0.1 14.7 0.0 0.1 0.0 0.1 0.0 0.7 4.8 0.1 0.2 0.2 0.0 0.0 512.9 0.0 0.1 1.9 0.0 0.0 0.0 3.7 1.4 0.0 0.1 0.0 149.2 0.0 24.4 0.0 0.0 3.8 1.2 0.3 0.0 13.1 0.0 0.8 0.0 88.4 7.0 0.2 0.0 7.5 0.0 0.6 0.0 0.0 0.0 1.7 0.0 2.5 4.4 1.0 6.5 0.1 0.0 0.0 0.0 44.8 0.0 0.1 FBLIM1 "CAL, FBLP-1, migfilin" ENSG00000162458 "Filamin binding LIM protein 1" Q8WUP2 1 15756607-15786594 "Predicted intracellular proteins" "Cell adhesion, Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 207.3;Paneth cells: 153.6;Peritubular cells: 191.5;Proximal enterocytes: 145.9;Sertoli cells: 144.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 255.9;TIME: 420.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA025287, HPA072750" Approved Enhanced "Nucleoli fibrillar center,Cell Junctions,Focal adhesion sites" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions, Focal adhesion sites" "Nucleoli fibrillar center" "HPA025287: AB_1848443, HPA072750: AB_2686554" "unprognostic (4.10e-2)" "prognostic unfavorable (4.07e-4)" "unprognostic (2.26e-1)" "unprognostic (5.33e-2)" "unprognostic (2.46e-2)" "unprognostic (1.52e-1)" "unprognostic (9.33e-2)" "unprognostic (8.77e-3)" "prognostic unfavorable (6.15e-4)" "unprognostic (2.02e-1)" "unprognostic (1.67e-1)" "unprognostic (1.09e-1)" "prognostic unfavorable (8.64e-4)" "unprognostic (8.33e-2)" "unprognostic (3.01e-1)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 32.4 17.9 2.7 21.5 3.3 0.8 28.1 3.2 4.8 43.2 5.2 75.6 82.2 75.7 15.6 24.1 43.5 69.8 45.6 2.5 2.4 26.7 7.1 39.3 9.6 2.6 3.2 39.1 27.5 36.2 11.0 29.4 2.9 47.0 53.2 1.8 31.7 63.1 5.4 16.8 86.1 47.1 2.5 27.6 64.0 12.8 3.8 2.8 17.6 5.6 6.8 44.6 29.3 2.6 34.2 17.2 15.9 0.6 3.7 8.1 21.6 55.2 84.3 38.4 30.4 6.0 48.8 0.3 114.5 87.8 67.3 62.5 11.3 121.0 19.2 0.3 6.6 0.2 4.7 31.7 98.5 0.2 0.6 39.7 81.7 31.9 75.1 82.7 255.9 2.0 1.2 7.6 13.2 0.8 0.6 1.1 16.5 50.9 25.0 0.1 0.4 1.0 51.4 22.1 0.2 38.9 29.0 3.4 6.0 33.9 6.8 0.6 420.4 50.7 7.1 0.8 25.7 0.4 1.0 0.5 8.0 0.2 0.5 1.7 0.3 0.3 0.2 0.1 0.2 0.3 0.2 0.2 0.1 0.5 0.3 0.3 0.8 0.4 0.2 0.4 0.1 0.1 2.7 3.3 3.2 4.8 2.5 2.4 2.6 3.2 2.9 2.5 3.8 2.6 10.8 12.8 18.1 0.0 3.1 86.3 82.7 41.4 20.5 3.7 28.6 23.9 37.1 47.1 30.6 16.5 6.2 8.9 4.8 207.3 0.0 99.1 3.4 13.6 75.9 19.2 46.0 0.0 0.7 53.5 114.2 29.3 133.5 20.5 18.9 9.4 55.0 2.5 5.6 1.7 5.5 54.8 26.4 1.9 23.5 4.0 80.2 5.8 14.2 2.8 2.7 9.1 1.0 1.0 1.2 113.0 153.6 191.5 1.2 29.8 145.9 2.5 11.6 6.4 144.7 11.9 64.8 2.8 1.9 17.4 62.8 19.4 6.0 6.6 53.8 62.6 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 753.6;tongue: 385.3" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 11.2;Skeletal myocytes: 8.7;Spermatogonia: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Region enriched" "Detected in some" 4 "hippocampal formation: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.9;CACO-2: 2.1;HMC-1: 2.2;MCF7: 3.0;OE19: 2.9;PC-3: 2.0;SiHa: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 960000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 0.1 0.9 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.0 69.2 0.3 5.3 0.0 0.0 8.1 0.0 0.1 0.2 6.1 0.0 0.2 0.2 0.4 0.4 0.7 0.3 0.0 4.3 49.7 0.0 0.1 0.1 1.2 0.0 0.0 4.2 3.3 753.6 0.2 0.9 0.0 0.9 0.0 36.1 1.4 1.4 0.2 0.3 385.3 0.9 0.3 0.0 0.0 0.3 1.3 0.0 1.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 1.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 2.9 2.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 2.8 0.6 0.0 0.1 0.2 0.1 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.6 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 6.1 0.0 0.7 0.3 0.1 0.9 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.5 1.3 0.0 0.0 11.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.2 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FBRSL1 KIAA1545 ENSG00000112787 "Fibrosin like 1" Q9HCM7 12 132489551-132585188 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "NB-4: 90.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049880 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA049880: AB_2680930" "unprognostic (2.02e-1)" "unprognostic (6.67e-2)" "unprognostic (1.88e-2)" "unprognostic (7.75e-2)" "unprognostic (3.21e-1)" "unprognostic (2.59e-2)" "unprognostic (1.29e-1)" "unprognostic (1.83e-1)" "unprognostic (2.25e-1)" "unprognostic (1.57e-1)" "unprognostic (2.77e-3)" "prognostic unfavorable (9.82e-4)" "prognostic favorable (1.17e-4)" "unprognostic (1.13e-1)" "unprognostic (3.39e-1)" "unprognostic (1.09e-2)" "prognostic favorable (7.21e-4)" 12.3 19.2 16.3 8.7 13.1 10.1 13.2 20.7 21.2 17.8 7.2 20.5 11.2 18.6 7.7 15.6 18.7 4.1 31.1 16.2 6.7 19.3 26.8 16.2 8.5 10.0 7.7 22.3 39.2 7.3 28.7 5.7 8.0 22.0 3.6 5.9 14.7 7.2 31.9 19.4 23.3 4.1 4.7 28.3 21.4 29.1 9.6 6.2 15.7 9.4 4.7 17.8 15.7 10.2 11.7 18.5 8.7 14.8 3.7 4.5 64.4 10.9 3.1 7.1 4.3 32.7 6.9 19.0 18.4 3.6 6.1 22.6 9.3 6.1 2.3 14.7 47.6 23.2 11.0 25.0 8.0 24.7 23.4 4.1 10.7 6.6 4.8 6.5 7.0 15.9 49.9 3.8 3.1 29.8 33.7 90.0 22.7 8.4 33.4 50.9 9.3 13.2 6.2 11.2 33.4 28.0 10.2 15.8 14.1 3.6 18.6 23.7 11.1 7.6 18.5 13.7 13.9 24.6 13.0 12.0 8.8 23.8 9.4 1.2 0.4 1.2 0.3 0.3 0.3 0.8 0.3 0.3 0.3 0.6 0.3 0.4 0.5 0.2 0.7 1.0 0.6 0.3 16.3 13.1 20.7 21.2 16.2 6.7 10.0 7.7 8.0 4.7 9.6 10.2 14.9 3.2 5.2 24.2 12.8 9.2 7.1 3.3 11.4 28.9 20.7 18.5 13.7 4.3 4.0 11.0 41.7 6.9 19.8 24.0 7.9 6.2 1.4 16.8 17.9 8.8 31.0 12.0 17.0 7.6 5.8 11.8 15.3 22.0 1.3 22.6 7.5 22.2 6.9 11.8 17.1 21.7 0.0 11.6 11.1 2.0 16.1 16.4 5.4 15.0 7.7 9.3 6.2 12.5 16.8 9.0 15.0 15.4 11.9 16.0 13.3 6.4 6.4 22.7 6.6 12.7 11.5 5.7 8.0 10.8 10.4 11.5 10.9 12.7 18.7 10.4 FBXL2 "FBL2, FBL3" ENSG00000153558 "F-box and leucine rich repeat protein 2" Q9UKC9 3 33277025-33403662 "Predicted intracellular proteins" "Host-virus interaction, Ubl conjugation pathway" Calmodulin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 48.8;Excitatory neurons: 125.0;Inhibitory neurons: 92.8;Late spermatids: 50.7;Oligodendrocyte precursor cells: 55.8;Oligodendrocytes: 49.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 5.7;LHCN-M2: 6.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003240, HPA061783" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003240: , HPA061783: AB_2684605" "unprognostic (5.73e-2)" "unprognostic (4.47e-2)" "unprognostic (7.92e-2)" "unprognostic (7.21e-2)" "unprognostic (3.68e-1)" "unprognostic (1.59e-1)" "unprognostic (1.10e-2)" "unprognostic (2.09e-1)" "unprognostic (3.16e-1)" "unprognostic (2.00e-1)" "unprognostic (4.31e-2)" "unprognostic (1.06e-1)" "prognostic favorable (3.35e-4)" "unprognostic (3.30e-3)" "unprognostic (9.72e-2)" "unprognostic (4.28e-2)" "unprognostic (5.90e-2)" 0.9 1.3 3.6 0.4 3.8 0.3 1.0 2.2 4.0 1.1 4.2 1.1 0.7 1.0 2.1 0.4 1.5 0.6 0.9 3.5 3.7 1.4 0.2 1.2 0.3 2.9 2.6 1.4 1.1 2.7 2.7 1.4 3.0 1.0 0.2 4.2 0.8 1.6 0.2 0.6 0.5 0.8 1.6 0.5 0.8 1.1 3.3 0.2 2.3 0.0 0.2 0.8 0.9 2.7 2.7 0.7 1.0 1.0 1.5 2.4 0.4 2.0 1.6 1.8 2.6 0.5 3.1 0.1 0.6 1.3 0.8 0.5 0.9 2.1 1.2 0.2 1.1 0.4 2.3 0.5 1.8 0.2 0.4 0.9 1.6 1.1 0.8 5.7 3.3 1.9 0.5 0.2 6.2 0.2 0.5 0.3 0.7 0.3 0.6 0.1 0.6 0.1 4.6 0.7 1.1 1.1 0.9 0.5 0.8 1.7 1.3 0.7 2.5 0.8 0.7 0.6 1.1 0.2 0.1 0.1 0.8 0.2 0.6 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.0 0.0 3.6 3.8 2.2 4.0 3.5 3.7 2.9 2.6 3.0 1.6 3.3 2.7 2.7 3.2 7.3 22.2 1.0 1.1 7.6 5.6 1.8 15.3 3.0 3.7 2.4 2.8 4.8 5.5 25.0 0.5 0.4 0.1 3.9 3.9 48.8 18.8 3.6 3.8 0.0 0.0 125.0 0.4 1.5 5.0 5.6 6.2 0.0 6.2 2.2 0.1 0.5 18.5 92.8 0.3 8.2 0.8 2.4 50.7 1.5 0.5 1.8 22.5 0.1 6.6 0.0 55.8 49.6 4.2 0.1 4.1 0.3 4.2 0.2 3.2 16.5 17.7 6.6 3.6 3.9 21.3 8.6 0.7 1.1 0.7 1.5 3.5 0.1 3.8 FBXO16 FBX16 ENSG00000214050 "F-box protein 16" Q8IX29 8 28348287-28490278 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 18.4;pituitary gland: 17.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 35.5;Excitatory neurons: 44.4;Inhibitory neurons: 43.6;Rod photoreceptor cells: 48.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 9.6" "Lineage enriched" "Detected in single" 10 "dendritic cells: 9.6" "Cell line enhanced" "Detected in many" "AF22: 20.3;Karpas-707: 22.4" "Low region specificity" "Detected in all" "HPA058676, HPA076472" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Vesicles, Plasma membrane, Cytosol" "HPA058676: AB_2683795, HPA076472: " "unprognostic (3.44e-1)" "unprognostic (1.44e-1)" "unprognostic (3.37e-3)" "unprognostic (5.56e-3)" "unprognostic (1.87e-1)" "unprognostic (1.40e-2)" "unprognostic (2.55e-3)" "unprognostic (4.95e-3)" "unprognostic (6.49e-2)" "prognostic favorable (6.70e-5)" "unprognostic (3.41e-3)" "unprognostic (4.90e-2)" "unprognostic (7.15e-2)" "unprognostic (1.71e-2)" "unprognostic (4.85e-2)" "unprognostic (2.72e-2)" "unprognostic (2.07e-1)" 0.5 1.8 3.9 0.9 5.0 2.2 2.6 6.8 7.0 4.1 2.9 1.6 2.0 1.1 18.4 0.7 4.4 1.4 1.4 4.6 3.9 3.2 6.0 1.5 1.4 1.1 1.7 0.7 4.7 7.1 17.3 0.6 2.0 3.5 2.0 14.3 3.4 5.1 1.1 0.4 2.9 0.7 0.3 1.2 2.2 4.2 3.5 0.6 7.0 0.9 2.8 1.2 0.7 4.3 16.5 2.9 20.3 7.5 0.5 0.0 0.3 0.2 0.5 3.0 5.5 3.1 4.6 5.8 7.2 0.1 8.1 5.1 2.3 3.5 3.0 2.6 3.6 2.7 0.3 1.7 0.0 3.5 1.9 0.2 10.8 0.7 3.2 1.5 0.0 5.6 1.1 22.4 1.0 5.7 0.5 5.0 3.9 2.2 4.5 0.2 4.5 8.2 3.9 2.4 13.1 5.4 0.4 3.3 9.5 3.5 13.8 5.9 0.6 1.6 5.8 3.2 3.0 5.2 5.0 5.2 6.8 0.7 3.5 0.3 0.1 0.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.2 0.1 0.2 0.9 0.0 0.1 9.6 0.2 0.1 3.9 5.0 6.8 7.0 4.6 3.9 1.1 1.7 2.0 0.3 3.5 4.3 0.0 3.2 4.1 7.5 1.7 0.1 3.0 10.9 5.2 8.2 3.9 3.4 2.1 8.6 7.9 3.7 35.5 0.6 0.0 0.5 7.9 5.3 12.1 13.5 1.3 0.2 10.2 0.0 44.4 4.6 0.4 0.9 1.5 6.4 0.0 1.9 0.4 1.9 2.7 5.0 43.6 3.9 4.1 0.8 2.3 12.4 1.2 0.4 0.0 2.8 0.0 9.3 0.0 23.6 3.2 3.1 0.4 0.7 11.1 1.7 0.2 4.7 23.4 48.6 0.0 0.5 1.8 10.5 5.6 1.2 0.0 0.0 0.5 4.2 1.0 1.7 FBXO38 "Fbx38, FLJ13962, MOKA, SP329" ENSG00000145868 "F-box protein 38" Q6PIJ6 5 148383935-148442836 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Ubl conjugation pathway" "Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034821, HPA041444" Approved Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA034821: AB_10669897, HPA041444: AB_2677484" "unprognostic (7.72e-2)" "unprognostic (5.75e-3)" "unprognostic (1.95e-2)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.70e-2)" "unprognostic (7.06e-2)" "unprognostic (5.43e-3)" "unprognostic (1.45e-1)" "unprognostic (1.12e-1)" "unprognostic (2.03e-1)" "unprognostic (6.29e-2)" "unprognostic (2.21e-3)" "unprognostic (1.31e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-1)" "unprognostic (4.70e-3)" 12.8 11.5 7.3 12.9 8.4 9.8 13.9 8.1 9.9 14.1 8.2 12.5 9.6 12.5 11.1 10.5 10.0 11.5 17.4 7.0 7.7 12.9 18.0 14.5 14.6 8.0 7.6 12.3 9.5 18.5 10.2 13.8 8.0 14.6 13.0 11.0 11.5 12.0 18.7 12.2 11.6 12.3 7.5 14.4 12.5 12.4 7.8 20.2 12.2 16.8 15.6 13.8 11.2 9.9 12.6 13.2 20.1 14.7 22.1 24.6 10.4 16.1 30.7 22.4 30.5 19.6 15.1 18.2 15.5 26.2 23.6 17.2 21.2 20.3 26.8 20.1 13.6 10.8 19.0 13.3 21.9 29.6 17.0 24.0 17.1 21.6 21.1 24.0 30.7 16.6 12.2 19.1 22.3 5.1 18.8 13.8 9.4 13.9 19.8 16.6 29.3 18.4 21.7 14.5 17.9 17.3 21.4 14.2 21.2 17.1 15.0 21.2 20.2 20.4 7.3 10.8 18.2 23.3 25.1 15.3 20.3 16.6 15.8 15.1 6.1 9.1 5.0 8.0 5.5 4.9 4.7 5.0 7.5 3.8 4.8 6.2 11.2 7.7 15.2 3.7 7.4 4.9 7.3 8.4 8.1 9.9 7.0 7.7 8.0 7.6 8.0 7.5 7.8 9.9 10.6 16.0 45.7 25.1 13.8 3.3 5.5 7.4 7.4 10.3 8.5 6.7 18.7 11.5 10.6 11.0 10.4 7.5 13.4 11.3 5.9 8.8 11.2 8.9 9.9 10.8 9.6 7.2 40.2 6.7 6.8 11.8 14.8 10.4 15.8 9.6 11.4 16.9 12.6 13.5 37.4 10.1 6.1 24.9 6.4 2.9 9.0 17.8 3.6 38.4 12.3 5.9 12.3 33.2 44.4 9.9 8.9 18.4 11.0 8.6 9.3 9.3 16.4 9.0 0.0 6.9 7.8 20.6 8.6 9.2 3.8 12.3 12.1 11.2 9.0 8.7 FBXO41 "Fbx41, KIAA1940" ENSG00000163013 "F-box protein 41" Q8TF61 2 73254682-73284478 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 13.9;Enteroendocrine cells: 12.0;Excitatory neurons: 28.8;Inhibitory neurons: 22.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in all" 4 "amygdala: 21.2;basal ganglia: 31.0;cerebral cortex: 42.3;hippocampal formation: 29.6;white matter: 24.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 46.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055246, HPA058386" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA055246: AB_2682758, HPA058386: AB_2683701" "unprognostic (1.15e-3)" "unprognostic (9.36e-2)" "unprognostic (2.17e-2)" "prognostic unfavorable (5.76e-4)" "unprognostic (1.74e-2)" "unprognostic (5.85e-2)" "unprognostic (1.55e-3)" "unprognostic (1.58e-1)" "unprognostic (7.97e-3)" "unprognostic (7.55e-2)" "unprognostic (9.13e-3)" "unprognostic (4.35e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (3.08e-2)" "unprognostic (1.24e-1)" "unprognostic (1.97e-1)" "unprognostic (1.11e-2)" 1.3 3.0 21.2 4.6 31.0 3.3 1.5 7.2 42.3 1.7 0.0 1.8 1.4 1.6 2.3 1.3 1.7 1.7 1.0 29.6 4.6 1.1 0.4 1.5 7.7 4.2 3.8 2.5 3.7 5.5 13.9 0.5 4.6 2.6 1.4 3.1 2.6 2.0 0.1 2.3 5.3 1.2 1.1 9.1 1.8 2.3 5.4 5.5 1.2 0.1 6.9 1.5 1.4 24.8 6.4 3.1 1.0 0.0 0.3 0.2 1.4 1.2 1.0 2.0 2.5 7.2 3.6 46.6 0.2 0.2 4.5 5.1 6.5 4.1 2.0 19.4 0.6 14.5 8.0 3.0 1.5 22.2 10.4 2.5 1.6 0.1 1.6 5.6 0.3 12.7 2.9 7.6 2.1 1.7 7.7 20.4 4.7 2.4 2.7 25.4 11.7 23.2 1.3 2.2 15.7 5.8 8.0 3.3 5.0 0.3 4.5 9.2 0.4 7.0 5.9 6.4 1.2 8.5 3.9 22.1 1.8 23.7 3.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 21.2 31.0 7.2 42.3 29.6 4.6 4.2 3.8 4.6 1.1 5.4 24.8 0.3 0.0 0.6 2.6 5.1 0.3 0.3 1.0 1.2 13.9 1.8 1.4 2.1 1.5 0.3 1.8 0.0 0.0 3.4 0.5 0.0 0.5 0.2 0.3 2.5 0.4 12.0 0.0 28.8 2.5 0.1 2.1 0.0 1.1 2.5 2.1 0.7 0.0 1.9 6.7 22.4 0.4 2.0 4.7 1.1 1.5 0.3 3.2 1.8 7.5 2.6 0.9 2.1 5.5 0.9 1.1 0.3 0.7 3.6 0.8 0.1 0.3 1.1 2.3 0.0 0.3 0.7 1.3 2.4 0.5 0.3 0.0 3.1 5.4 0.8 0.2 FBXW11 "BTRC2, BTRCP2, Fbw11, Fbw1b, FBXW1B, Hos, KIAA0696" ENSG00000072803 "F-box and WD repeat domain containing 11" Q9UKB1 5 171861549-172006873 "Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Host-virus interaction, Ubl conjugation pathway, Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072204 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Vesicles, Plasma membrane" Nucleoplasm "HPA072204: AB_2686493" "unprognostic (4.04e-3)" "unprognostic (1.27e-1)" "unprognostic (2.69e-2)" "unprognostic (5.79e-2)" "unprognostic (1.39e-1)" "unprognostic (1.06e-1)" "unprognostic (1.90e-2)" "unprognostic (1.63e-1)" "unprognostic (6.87e-2)" "unprognostic (9.43e-2)" "unprognostic (1.53e-1)" "unprognostic (8.14e-3)" "unprognostic (2.38e-3)" "unprognostic (1.57e-1)" "unprognostic (1.54e-1)" "unprognostic (3.76e-3)" "unprognostic (1.76e-1)" 19.5 20.4 33.3 13.6 38.2 8.2 17.0 34.7 41.6 19.9 27.4 14.6 12.6 22.9 12.4 24.2 27.0 17.5 36.1 38.0 35.5 23.0 20.7 17.6 16.7 33.3 34.4 25.6 29.1 33.1 14.2 13.9 33.1 19.0 16.0 37.2 13.5 20.3 34.5 13.7 13.2 26.1 34.4 18.1 20.0 14.3 37.7 17.3 21.1 35.6 22.0 19.2 15.8 42.4 35.4 35.6 52.0 45.2 39.9 40.2 26.4 37.1 51.7 45.0 54.9 36.7 23.1 32.5 44.3 46.4 72.0 22.8 37.6 56.3 74.6 42.7 37.3 26.2 35.0 28.5 35.4 29.8 36.0 28.5 38.2 36.8 59.8 48.5 38.6 27.3 16.6 31.7 55.7 26.5 20.7 15.3 19.8 20.8 39.5 30.1 43.7 22.0 34.8 29.2 21.6 37.2 32.9 27.3 70.8 38.7 34.2 31.0 33.8 44.3 22.0 27.4 37.2 31.8 38.9 22.2 31.3 27.8 34.6 25.4 7.3 7.2 5.8 5.1 6.1 8.5 4.8 5.7 7.3 8.4 4.3 5.7 7.1 14.1 5.7 8.6 5.7 6.6 33.3 38.2 34.7 41.6 38.0 35.5 33.3 34.4 33.1 34.4 37.7 42.4 35.4 25.6 21.2 75.4 52.7 19.1 15.6 21.8 32.5 43.5 26.4 22.1 59.1 42.9 20.8 27.6 8.4 8.5 49.8 25.1 43.0 33.7 32.9 42.0 47.9 26.3 28.8 27.4 86.5 36.9 7.8 24.7 38.2 51.0 20.8 25.8 29.3 43.1 12.8 35.3 85.3 21.6 20.3 29.6 25.3 34.3 29.5 26.6 12.4 62.8 24.6 63.6 16.5 75.9 94.4 54.1 14.9 28.6 36.5 30.2 21.5 52.4 17.1 34.3 46.0 28.2 33.5 34.5 16.0 28.7 23.7 12.0 28.8 17.2 15.0 32.9 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FCGBP FC(GAMMA)BP ENSG00000275395 "Fc fragment of IgG binding protein" 19 39863323-39934626 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 206.9;salivary gland: 85.4;stomach 1: 85.5;thyroid gland: 99.9" "Cell type enriched" "Detected in many" 9 "Intestinal goblet cells: 6081.9" "Cancer enhanced" "Detected in all" "colorectal cancer: 63.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.6;Daudi: 1.8;JURKAT: 1.7;MOLT-4: 1.8;RH-30: 7.1" "HPA003517, HPA003564" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytokinetic bridge" "Secreted in other tissues" Yes NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 9: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Golgi apparatus, Cytokinetic bridge" "HPA003517: AB_1078838, HPA003564: AB_2231648" "unprognostic (1.65e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-3)" "unprognostic (1.77e-2)" "unprognostic (2.04e-2)" "prognostic favorable (1.28e-5)" "prognostic unfavorable (4.74e-5)" "unprognostic (1.36e-2)" "unprognostic (1.83e-1)" "prognostic unfavorable (9.70e-6)" "unprognostic (9.44e-2)" "unprognostic (3.03e-2)" "unprognostic (5.92e-3)" "unprognostic (8.60e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (4.27e-4)" "unprognostic (2.08e-1)" 5.9 10.0 5.1 14.0 7.2 0.4 3.2 4.0 8.4 56.4 15.0 206.9 68.7 1.2 0.6 4.6 9.8 49.2 2.9 5.6 6.8 11.3 1.0 1.9 0.9 20.1 10.6 3.7 4.9 0.5 3.4 2.9 11.1 3.8 67.7 0.6 85.4 1.4 0.4 14.8 148.7 2.6 5.9 1.5 85.5 2.9 14.0 1.5 99.9 0.0 0.7 3.4 1.6 12.0 0.0 4.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.7 0.0 0.2 0.0 0.1 1.8 0.6 0.1 1.5 0.3 0.1 7.1 1.6 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.2 0.4 0.1 0.1 0.5 0.0 0.3 0.1 0.0 0.0 0.1 5.1 7.2 4.0 8.4 5.6 6.8 20.1 10.6 11.1 5.9 14.0 12.0 0.6 3.2 5.1 2.6 4.6 3.7 1.9 15.8 1.2 1.1 1.3 3.4 2.8 70.1 60.0 25.8 0.0 0.7 1.8 622.2 0.0 5.2 7.2 4.2 0.3 26.7 81.1 0.0 0.6 0.9 0.4 1.9 552.0 4.0 15.9 0.4 0.7 1.3 44.0 0.0 0.4 6081.9 2.0 30.2 12.6 9.2 0.9 21.6 8.8 15.9 0.9 0.4 1.0 0.5 0.2 3.9 253.6 0.0 2.1 13.8 413.5 1.2 11.0 2.0 59.2 0.5 1.1 0.5 2.4 0.4 6.8 0.4 5.6 0.9 191.4 164.1 FCGR1A "CD64, CD64A" ENSG00000150337 "Fc fragment of IgG receptor Ia" P12314 1 149782671-149791675 "CD markers, FDA approved drug targets, Predicted membrane proteins" "Immunity, Innate immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 93.3;lymphoid tissue: 41.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 283.3;Kupffer cells: 140.9;Late spermatids: 64.9;Macrophages: 94.9" "Cancer enriched" "Detected in many" 4 "glioma: 10.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 131.5;intermediate monocyte: 54.7;myeloid DC: 35.6;neutrophil: 93.4" "Group enriched" "Detected in many" 53 "dendritic cells: 35.6;granulocytes: 93.4;monocytes: 131.5" "Cell line enriched" "Detected in some" 5 "THP-1: 191.6" "Low region specificity" "Detected in all" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (5.27e-2)" "unprognostic (2.89e-2)" "unprognostic (2.34e-2)" "unprognostic (7.97e-2)" "unprognostic (8.44e-3)" "unprognostic (1.73e-1)" "unprognostic (7.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.98e-2)" "unprognostic (6.18e-2)" "prognostic unfavorable (4.83e-8)" "unprognostic (1.28e-1)" "unprognostic (4.51e-2)" "unprognostic (9.99e-2)" "unprognostic (9.03e-2)" 12.2 7.2 8.4 41.3 8.9 17.9 3.6 8.8 12.8 4.2 8.4 2.3 1.1 1.6 93.3 1.7 1.8 8.2 2.2 8.6 9.4 2.8 4.2 28.6 14.4 14.6 10.6 2.3 4.3 2.7 2.5 32.6 13.0 1.6 2.1 2.3 1.9 2.4 0.3 0.4 1.3 19.1 13.2 12.5 2.1 3.7 12.2 1.4 1.4 0.8 0.8 14.7 0.8 18.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 13.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 41.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.1 0.3 191.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 24.4 0.0 2.0 131.5 1.6 0.0 54.7 0.7 1.6 0.0 0.3 35.6 0.0 0.0 0.1 93.4 0.0 11.8 0.9 0.3 48.5 8.4 8.9 8.8 12.8 8.6 9.4 14.6 10.6 13.0 13.2 12.2 18.9 0.3 0.0 3.1 0.0 0.8 0.1 0.0 0.0 0.6 1.5 0.2 0.8 1.7 1.5 1.3 0.0 2.1 2.7 0.0 0.0 0.0 0.0 30.8 0.1 0.1 9.3 0.0 2.7 0.1 0.0 1.3 1.0 0.0 0.1 0.0 0.2 1.8 0.5 283.3 0.0 0.1 0.0 0.0 140.9 6.0 64.9 0.3 94.9 0.0 7.5 34.7 0.3 0.0 0.5 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.2 0.7 1.3 6.6 0.2 0.3 0.6 0.4 0.1 0.0 4.1 0.6 0.1 0.1 0.0 FCGR1B CD64b ENSG00000198019 "Fc fragment of IgG receptor Ib" Q92637 1 121087345-121097161 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 51.5;lymphoid tissue: 18.9" "Cell type enhanced" "Detected in some" "Hofbauer cells: 86.5;Kupffer cells: 51.5;Late spermatids: 14.6;Macrophages: 36.6;monocytes: 16.4;Sertoli cells: 19.7" "Cancer enriched" "Detected in single" 4 "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 31.2;neutrophil: 36.3" "Group enriched" "Detected in many" 4 "granulocytes: 36.3;monocytes: 31.2" "Group enriched" "Detected in some" 6 "NB-4: 19.8;THP-1: 73.9" HPA026910 Uncertain "Golgi apparatus,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Golgi apparatus, Plasma membrane" "HPA026910: " "unprognostic (3.21e-2)" "unprognostic (4.35e-2)" "unprognostic (1.13e-2)" "unprognostic (2.84e-1)" "unprognostic (1.85e-1)" "unprognostic (9.60e-2)" "unprognostic (1.56e-2)" "unprognostic (6.42e-2)" "unprognostic (3.10e-2)" "unprognostic (8.17e-2)" "unprognostic (1.91e-1)" "unprognostic (3.65e-1)" "unprognostic (3.24e-10)" "unprognostic (8.99e-2)" "unprognostic (2.85e-2)" "unprognostic (7.86e-3)" "unprognostic (8.93e-2)" 5.0 3.0 4.4 18.9 4.5 6.6 1.8 4.5 7.8 1.0 3.7 0.7 0.5 0.7 51.5 0.7 0.8 1.9 1.1 4.6 4.7 1.4 1.7 6.8 2.2 6.1 5.7 0.6 2.6 0.7 1.0 11.0 6.2 0.8 0.8 0.8 0.9 0.6 0.4 0.2 0.7 5.8 6.0 7.2 0.9 0.7 6.2 0.4 2.1 0.1 0.3 4.0 0.4 6.4 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 5.9 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.0 0.0 19.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.1 0.0 0.3 1.0 73.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 31.2 0.6 0.0 19.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 36.3 0.0 12.4 0.3 0.0 8.8 4.4 4.5 4.5 7.8 4.6 4.7 6.1 5.7 6.2 6.0 6.2 6.4 0.4 0.0 2.0 0.0 0.7 0.0 0.0 0.0 0.0 0.6 0.1 0.6 2.2 0.0 0.6 0.0 2.1 0.8 0.1 0.1 0.0 0.0 7.7 0.2 0.2 2.0 0.0 0.8 0.0 0.0 0.3 1.1 0.0 0.0 0.0 0.4 0.4 0.3 86.5 3.3 0.1 0.0 0.0 51.5 4.1 14.6 1.2 36.6 0.0 11.2 16.4 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.4 19.7 0.6 0.1 0.5 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.1 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FCHSD2 "KIAA0769, SH3MD3" ENSG00000137478 "FCH and double SH3 domains 2" O94868 11 72836745-73142318 "Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 219.6;Microglial cells: 387.8;Oligodendrocyte precursor cells: 471.0;Oligodendrocytes: 198.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 164.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038545, HPA038546" Uncertain Approved "Nuclear speckles,Plasma membrane,Actin filaments,Focal adhesion sites" Yes No "Cluster 10: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments" "Nuclear speckles, Focal adhesion sites" "HPA038545: AB_2676074, HPA038546: AB_10673013" "unprognostic (1.80e-2)" "unprognostic (1.50e-2)" "prognostic favorable (1.71e-4)" "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.62e-3)" "unprognostic (1.41e-2)" "unprognostic (2.62e-1)" "unprognostic (1.27e-2)" "unprognostic (2.56e-1)" "unprognostic (3.69e-2)" "unprognostic (6.16e-2)" "unprognostic (2.89e-3)" "unprognostic (2.02e-1)" "unprognostic (4.70e-1)" "unprognostic (2.92e-1)" "unprognostic (1.23e-1)" 22.2 19.2 43.3 33.4 47.9 28.6 16.8 31.5 38.7 14.9 34.6 14.5 8.9 16.0 6.9 11.7 13.8 22.6 25.5 37.0 44.5 13.0 17.6 23.9 45.2 36.6 36.4 32.3 10.4 9.9 8.1 31.2 35.4 11.6 14.4 19.6 9.3 13.8 8.8 9.0 17.7 17.2 32.5 42.3 13.1 22.6 41.3 28.5 14.9 14.7 46.1 21.6 11.7 45.0 14.2 12.3 26.0 31.3 9.8 23.9 21.8 26.7 50.6 14.8 12.0 9.6 21.0 76.3 31.3 31.0 15.6 20.0 15.3 14.1 21.0 27.2 7.0 64.2 14.3 33.4 25.7 30.6 7.6 14.6 15.6 15.1 17.7 33.4 35.7 26.7 13.7 49.6 19.5 16.1 36.4 54.7 5.5 15.6 13.8 56.4 39.8 164.1 24.8 21.4 13.1 16.9 9.6 16.2 31.9 12.2 12.4 23.7 47.9 45.9 18.5 32.9 7.5 46.8 29.4 71.2 8.4 51.4 13.8 18.3 8.4 18.7 2.8 5.1 1.9 22.2 2.8 3.2 8.1 26.9 3.2 4.1 19.9 2.0 3.0 32.3 3.2 3.6 43.3 47.9 31.5 38.7 37.0 44.5 36.6 36.4 35.4 32.5 41.3 45.0 47.3 9.6 14.0 114.9 76.7 8.5 5.2 3.6 9.1 13.5 5.9 4.7 16.0 8.6 6.1 3.7 25.0 12.4 39.4 1.9 1.9 4.1 6.2 6.6 8.3 30.2 4.8 19.4 79.4 6.2 9.2 9.4 7.7 5.4 2.5 33.6 46.1 11.3 19.9 10.1 219.6 7.7 4.1 30.8 29.9 10.0 10.8 32.8 5.4 387.8 20.6 10.6 5.2 471.0 198.1 5.3 5.7 16.6 70.1 3.8 1.8 3.5 3.9 17.0 6.6 13.0 26.1 9.6 13.0 7.1 5.8 12.0 14.9 6.0 3.7 4.8 FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35351552-35353862 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 2.8;brain: 4.8;ovary: 2.5;pancreas: 4.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;granulocytes: 1.3;Granulosa cells: 1.4" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-698: 1.6" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" 0.0 0.0 1.5 0.1 2.1 2.8 0.0 1.4 1.9 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 1.5 0.0 0.0 0.1 0.4 2.1 1.6 2.5 4.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.3 0.6 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 1.9 1.3 1.5 2.1 1.6 2.1 1.3 1.9 4.8 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.3 1.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FGD1 "FGDY, ZFYVE3" ENSG00000102302 "FYVE, RhoGEF and PH domain containing 1" P98174 X 54445454-54496234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 16.1;Granulosa cells: 12.6;Inhibitory neurons: 15.2" "Cancer enhanced" "Detected in all" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000911, HPA076516" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA000911: AB_1078853, HPA076516: " "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (8.74e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-2)" "unprognostic (2.77e-3)" "unprognostic (1.49e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-2)" "unprognostic (4.92e-2)" "unprognostic (3.41e-2)" "unprognostic (9.40e-3)" 3.9 5.1 8.2 1.6 6.2 0.0 3.6 5.3 7.6 7.0 2.4 5.6 1.0 7.1 1.6 5.8 5.1 2.2 5.0 8.3 5.2 3.5 1.1 2.8 0.5 3.8 4.1 7.4 3.2 3.6 3.6 3.4 3.7 4.3 1.6 1.6 3.4 3.3 1.3 5.4 2.8 5.4 3.5 2.4 3.5 2.4 4.9 0.4 3.3 1.0 1.0 4.8 5.4 4.6 18.5 6.9 13.2 19.3 7.8 13.8 6.2 10.4 12.8 10.6 8.5 0.6 0.4 0.0 8.2 19.9 9.6 5.3 14.6 9.0 5.8 1.0 8.9 0.0 5.0 2.2 8.3 0.0 0.0 11.3 5.6 16.1 7.6 9.4 9.7 2.3 2.0 0.0 8.4 2.4 0.7 0.0 12.6 0.0 10.2 9.4 6.7 0.0 9.1 0.3 13.1 11.9 10.3 0.2 16.6 21.0 10.3 0.4 6.9 10.5 8.7 23.0 9.4 0.1 0.2 0.1 11.0 0.6 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.2 5.3 7.6 8.3 5.2 3.8 4.1 3.7 3.5 4.9 4.6 3.2 0.0 0.0 4.6 0.0 2.9 1.2 2.0 5.2 2.5 3.2 3.9 3.4 0.0 0.7 0.0 0.0 0.5 0.1 0.2 0.0 1.6 0.4 1.3 7.0 4.2 1.2 0.0 16.1 1.1 1.0 5.1 1.5 2.1 0.0 12.6 2.9 0.3 0.4 1.7 15.2 1.0 0.0 0.0 1.0 0.6 2.8 0.1 7.2 5.6 0.0 2.3 0.0 7.1 1.8 0.5 0.5 4.1 0.1 1.6 0.1 1.4 0.3 3.5 0.0 2.3 4.0 0.3 2.2 5.5 4.1 0.3 0.1 2.9 2.8 1.0 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FGFR2 "BEK, CD332, CEK3, CFD1, ECT1, JWS, K-SAM, KGFR, TK14, TK25" ENSG00000066468 "Fibroblast growth factor receptor 2" P21802 10 121478332-121598458 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Apoptosis "Heparin-binding, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Craniosynostosis, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Lacrimo-auriculo-dento-digital syndrome, Mental retardation, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 273.8;choroid plexus: 198.1" "Group enriched" "Detected in many" 5 "Astrocytes: 228.2;Cholangiocytes: 213.1;Oligodendrocytes: 562.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 24 "basophil: 13.2;eosinophil: 3.8" "Lineage enriched" "Detected in single" 58 "granulocytes: 13.2" "Cell line enhanced" "Detected in many" "AN3-CA: 189.0;BEWO: 60.9;CACO-2: 49.6;HaCaT: 55.6;HAP1: 63.7;NTERA-2: 57.8;T-47d: 49.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010886, HPA035305" Uncertain Supported "Nucleoplasm,Vesicles,Cell Junctions" "Secreted - unknown location" NA NA 1200000 "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB010886: AB_259379, HPA035305: AB_10672862" "unprognostic (5.53e-2)" "prognostic favorable (8.79e-4)" "unprognostic (1.08e-1)" "unprognostic (5.23e-2)" "unprognostic (1.73e-1)" "prognostic favorable (9.32e-4)" "unprognostic (1.53e-1)" "unprognostic (4.96e-3)" "unprognostic (1.74e-1)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (3.74e-2)" "unprognostic (1.01e-1)" "unprognostic (6.11e-2)" "unprognostic (2.54e-1)" "unprognostic (6.93e-2)" "unprognostic (2.25e-1)" 5.7 21.3 103.9 8.2 186.8 0.3 22.9 178.9 198.9 19.7 198.1 44.8 10.4 54.6 15.3 25.2 29.6 31.3 5.6 109.9 124.7 26.3 41.0 30.9 2.9 250.9 185.9 18.0 31.0 61.0 6.8 15.7 220.5 27.4 21.2 1.2 59.1 54.6 0.5 109.3 12.2 43.6 165.5 0.8 22.5 7.6 148.0 10.1 54.6 0.2 9.1 16.6 27.4 273.8 7.2 0.4 30.2 189.0 0.1 0.0 60.9 0.4 0.0 0.0 0.0 49.6 1.1 0.1 12.5 2.8 0.1 55.6 63.7 13.0 0.0 0.1 12.7 0.0 0.2 1.2 1.5 0.2 11.7 0.1 26.2 0.0 0.6 0.0 0.0 0.3 0.2 0.2 0.0 11.7 0.2 0.1 57.8 8.7 0.0 0.1 0.0 7.5 18.0 15.8 0.5 0.5 0.4 33.4 0.0 36.6 49.3 0.0 0.1 0.3 8.5 0.2 0.7 0.1 0.1 0.0 0.3 0.0 0.5 13.2 0.0 3.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 103.9 186.8 178.9 198.9 109.9 124.7 250.9 185.9 220.5 165.5 148.0 273.8 1.4 19.2 36.0 228.2 0.6 40.1 34.3 18.4 58.6 0.2 8.7 25.4 9.1 213.1 38.4 36.8 0.0 16.5 0.3 7.3 0.0 7.4 4.1 28.1 4.4 1.0 2.4 2.7 14.8 0.2 3.0 9.0 13.3 53.1 0.0 0.1 1.8 5.0 2.3 0.0 31.2 40.8 10.2 0.6 4.4 9.6 1.2 1.1 5.4 10.3 0.6 2.0 1.0 6.0 562.5 0.7 3.0 6.0 0.1 15.0 1.8 13.6 15.3 0.2 0.0 1.6 2.6 0.7 9.9 18.7 27.7 4.0 1.5 0.4 3.8 31.4 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in many" "Astrocytes: 609.8;Inhibitory neurons: 450.5;Microglial cells: 337.3;Oligodendrocyte precursor cells: 1086.7;Oligodendrocytes: 1111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 17.5;U-266/70: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 5.6 24.4 13.7 6.2 18.3 8.0 9.0 13.0 17.3 5.4 94.0 6.9 6.4 3.5 6.9 5.0 6.6 9.8 15.8 19.7 16.4 24.9 9.6 4.7 7.6 18.9 17.0 6.8 13.0 18.1 7.9 3.0 18.9 5.3 5.8 7.6 8.5 4.7 10.6 8.1 5.3 4.7 15.0 5.0 8.6 5.5 15.9 12.1 11.7 7.2 5.3 6.7 4.2 19.8 0.1 0.0 1.4 0.0 0.6 0.1 2.5 0.1 0.2 0.1 0.0 2.7 4.2 4.0 0.7 0.1 3.0 0.0 12.7 3.2 0.0 2.2 5.0 3.3 2.0 6.4 3.3 8.7 0.1 9.1 5.2 0.2 6.9 0.3 0.0 3.7 2.5 11.9 0.2 3.6 15.2 6.7 1.2 12.2 0.9 11.3 0.0 17.5 15.3 2.0 2.9 4.3 1.5 9.9 10.1 5.3 0.4 0.2 0.0 1.7 0.4 0.1 2.4 34.6 11.3 0.0 4.0 0.1 1.9 6.8 4.6 0.5 2.2 2.9 1.4 4.1 17.2 1.8 5.7 3.1 87.6 15.6 0.8 7.2 1.3 5.8 20.5 11.9 13.7 18.3 13.0 17.3 19.7 16.4 18.9 17.0 18.9 15.0 15.9 19.8 4.1 6.4 10.6 609.8 19.7 7.6 20.7 30.0 46.7 12.6 41.2 31.2 10.0 38.6 17.5 27.6 58.4 42.0 12.4 6.9 78.2 19.1 45.8 14.6 7.9 7.0 7.7 17.7 276.6 4.7 8.5 10.1 18.3 19.0 5.7 25.7 14.6 23.4 20.9 30.3 450.5 12.9 22.4 10.2 7.1 163.0 19.3 12.9 12.4 337.3 8.6 19.7 6.2 1086.7 1111.0 9.7 15.0 9.8 23.8 12.0 20.7 126.6 12.4 20.7 0.0 10.7 6.2 19.1 7.5 33.7 11.2 32.7 11.5 23.0 20.1 18.8 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FIBCD1 FLJ14810 ENSG00000130720 "Fibrinogen C domain containing 1" Q8N539 9 130902438-130939286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 9.9;brain: 26.7;parathyroid gland: 12.5" "Cell type enhanced" "Detected in some" "Early spermatids: 19.6;Exocrine glandular cells: 30.1;Intestinal goblet cells: 24.5;Ionocytes: 26.4;Late spermatids: 36.1;Pancreatic endocrine cells: 28.6;Spermatogonia: 16.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "non-classical monocyte: 1.1" "Lineage enriched" "Detected in single" 11 "monocytes: 1.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 13.7;MCF7: 32.8;OE19: 22.9;RPTEC TERT1: 24.4;THP-1: 12.5;U-2 OS: 14.1;U-251 MG: 13.5" "Group enriched" "Detected in many" 4 "basal ganglia: 17.6;hippocampal formation: 68.4" "Region enriched" "Detected in many" 5 "hippocampal formation: 57.3" HPA055353 Approved Approved "Cell Junctions" NA NA 19000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Cell Junctions" "HPA055353: AB_2682791" "unprognostic (1.18e-3)" "unprognostic (2.70e-1)" "unprognostic (4.69e-2)" "unprognostic (5.63e-2)" "unprognostic (9.11e-2)" "unprognostic (1.62e-1)" "unprognostic (4.16e-5)" "unprognostic (1.83e-3)" "unprognostic (3.14e-1)" "unprognostic (1.28e-1)" "unprognostic (2.05e-2)" "unprognostic (4.45e-2)" "unprognostic (1.42e-6)" "unprognostic (1.66e-1)" "unprognostic (5.53e-2)" "unprognostic (6.68e-3)" "unprognostic (2.77e-1)" 0.1 9.9 8.0 0.0 1.8 0.0 0.5 0.0 15.8 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 0.2 0.5 26.7 1.4 0.1 0.0 2.1 0.0 8.3 6.3 0.1 0.0 12.5 0.1 0.9 5.2 0.1 0.7 1.3 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.3 0.1 6.6 5.4 0.0 0.0 0.0 0.0 0.9 0.1 2.7 0.3 3.5 1.2 0.0 0.1 0.0 0.0 5.9 8.7 0.4 1.2 0.0 3.7 0.0 2.3 0.3 6.3 2.0 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.4 0.2 0.3 0.0 0.1 3.9 0.0 13.7 0.0 0.0 0.7 0.0 0.0 32.8 0.0 2.8 2.1 22.9 0.6 0.0 5.7 0.4 24.4 0.0 0.2 0.0 1.1 0.1 0.8 0.9 2.0 12.5 0.0 1.3 14.1 0.1 13.5 0.0 0.0 0.0 4.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.1 8.0 1.8 0.0 15.8 26.7 1.4 8.3 6.3 5.2 0.0 5.4 2.7 0.2 0.0 0.0 0.3 0.0 0.0 0.9 5.0 0.0 3.2 0.8 0.0 1.3 0.0 2.3 1.8 0.0 11.6 0.0 10.4 0.0 0.3 19.6 0.0 0.1 0.4 0.0 0.0 0.3 30.1 0.9 0.9 0.0 0.0 0.0 0.8 0.0 0.0 1.1 3.3 0.3 24.5 26.4 0.0 0.0 36.1 0.6 0.5 0.0 1.9 0.4 0.6 0.0 0.0 0.1 28.6 6.3 3.4 0.0 0.7 2.5 0.1 2.1 0.2 0.0 0.0 0.8 9.5 16.3 0.0 0.0 4.0 0.0 0.9 6.7 1.5 FIGN ENSG00000182263 "Fidgetin, microtubule severing factor" Q5HY92 2 163593396-163736012 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 161.3;Inhibitory neurons: 82.9;Oligodendrocyte precursor cells: 309.6;Oligodendrocytes: 129.4;Sertoli cells: 72.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 34 "basophil: 3.3" "Lineage enriched" "Detected in single" 34 "granulocytes: 3.3" "Cell line enhanced" "Detected in many" "AF22: 18.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034987, HPA057919" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane, Cytosol" "Vesicles, Cell Junctions" "HPA034987: AB_10669681, HPA057919: " "unprognostic (3.93e-2)" "unprognostic (8.30e-3)" "unprognostic (1.48e-1)" "unprognostic (7.68e-5)" "unprognostic (3.45e-2)" "unprognostic (8.98e-4)" "unprognostic (5.23e-3)" "unprognostic (7.65e-3)" "unprognostic (2.33e-1)" "unprognostic (1.64e-1)" "unprognostic (2.07e-2)" "unprognostic (3.24e-2)" "unprognostic (3.85e-3)" "unprognostic (3.22e-2)" "unprognostic (2.69e-1)" "unprognostic (4.10e-2)" "unprognostic (3.78e-2)" 3.1 2.0 3.9 0.4 5.0 0.8 2.0 2.3 4.4 2.4 0.0 2.6 0.4 1.1 1.2 0.6 1.9 1.1 3.3 2.5 5.4 1.9 3.2 1.4 0.6 3.0 4.2 4.6 2.9 0.4 2.6 1.1 3.9 1.6 0.7 1.4 2.6 2.7 1.0 1.0 1.4 0.9 1.8 3.0 1.8 1.1 4.6 0.2 1.1 1.7 0.2 1.7 2.4 5.1 6.4 2.3 18.6 0.0 0.0 0.0 6.8 2.4 1.6 1.7 3.2 0.0 2.2 0.0 6.6 2.6 3.4 0.9 6.2 2.6 1.3 0.0 4.6 0.0 4.7 4.6 1.5 0.0 0.0 0.8 2.2 3.3 9.0 2.6 4.0 0.0 0.0 0.0 5.1 1.6 0.0 0.0 7.9 0.4 2.9 0.0 6.3 0.0 4.2 2.1 2.9 2.5 0.0 1.8 1.7 10.3 2.0 0.0 0.4 7.6 6.8 0.0 5.1 1.1 0.0 0.0 2.3 0.0 4.3 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 5.0 2.3 4.4 2.5 5.4 3.0 4.2 3.9 1.8 4.6 5.1 2.9 6.4 7.3 161.3 0.7 1.9 0.1 2.8 1.8 24.4 5.7 2.7 19.4 20.0 3.0 12.9 0.0 21.2 0.2 0.1 1.9 3.7 3.8 0.7 0.7 2.1 0.0 0.0 53.4 1.5 7.4 11.6 4.1 1.6 0.0 23.6 7.9 13.5 1.4 6.7 82.9 0.0 4.1 0.0 1.6 6.4 51.9 0.6 17.8 28.1 0.0 4.3 0.0 309.6 129.4 1.1 0.0 34.3 0.0 1.8 0.0 8.1 4.0 2.1 72.3 16.6 17.8 1.1 1.2 1.0 0.4 16.8 0.2 7.0 0.0 0.0 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 929.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 510000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 64.7 127.6 185.1 77.5 187.6 50.1 58.3 192.7 234.7 113.1 210.8 105.7 136.3 81.1 397.7 68.4 94.4 77.2 117.4 185.0 196.9 122.7 197.3 62.7 70.7 199.9 199.6 75.3 280.1 160.4 200.9 73.1 197.7 92.5 84.2 37.1 208.9 146.7 33.3 60.9 107.3 72.6 183.4 67.5 113.4 74.7 194.3 59.0 187.6 48.4 70.4 85.7 61.6 196.0 101.2 144.8 82.8 165.9 178.5 98.2 94.6 132.9 146.4 108.8 101.4 148.1 257.0 80.8 195.4 186.5 148.2 134.7 70.5 121.0 51.3 101.4 54.5 90.0 196.5 158.3 231.6 74.5 125.5 116.0 169.3 145.4 163.5 156.9 86.9 76.6 61.0 253.6 138.1 186.7 85.1 112.6 92.6 211.1 130.0 70.8 70.9 299.2 198.9 120.7 110.0 91.3 85.4 263.2 147.9 59.5 98.1 69.5 68.9 123.8 100.9 182.8 72.6 128.5 48.6 69.0 156.7 80.6 142.8 276.8 173.1 25.9 178.9 191.2 230.8 170.1 139.2 176.4 172.2 165.0 90.4 131.5 68.6 162.9 162.7 929.1 55.9 126.7 185.1 187.6 192.7 234.7 185.0 196.9 199.9 199.6 197.7 183.4 194.3 196.0 129.5 147.4 168.0 20.9 179.7 164.4 251.0 447.2 125.2 86.4 205.0 185.4 134.7 275.9 270.6 389.9 22.9 279.8 174.4 534.1 412.8 270.8 126.4 212.5 206.3 138.6 342.6 41.4 11.3 254.2 386.9 167.0 179.4 258.5 144.0 146.5 148.5 754.4 228.4 32.0 14.8 508.2 305.2 100.1 201.7 99.0 230.2 140.7 300.6 16.9 151.7 181.7 111.2 11.1 20.6 292.2 424.7 255.1 765.2 315.5 594.7 792.2 241.9 83.3 184.1 138.4 221.3 327.1 282.1 136.6 168.1 620.5 123.6 138.8 339.4 312.0 FLACC1 ALS2CR12 ENSG00000155749 "Flagellum associated containing coiled-coil domains 1" Q96Q35 2 201288271-201357398 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.8;testis: 17.1" "Cell type enriched" "Detected in single" 8 "Cardiomyocytes: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4;U-2197: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035793 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "HPA035793: AB_10602429" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.40e-3)" "unprognostic (1.40e-5)" "unprognostic (1.37e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-1)" "unprognostic (6.23e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (2.23e-1)" "unprognostic (8.25e-2)" 0.9 1.1 3.9 1.0 4.3 5.0 0.5 2.8 3.9 0.7 9.8 0.8 0.5 0.7 1.1 1.2 8.3 1.1 4.5 5.0 3.2 1.3 0.7 2.5 1.6 5.8 6.4 0.3 0.9 0.7 1.1 0.8 3.7 0.5 1.0 3.3 1.1 0.8 1.8 1.2 1.0 0.6 4.2 0.8 0.5 17.1 3.0 0.7 1.6 0.4 0.5 0.6 0.4 3.7 0.1 0.2 1.1 0.7 2.7 1.1 0.0 0.8 0.3 0.7 0.4 0.0 0.3 0.2 0.6 1.2 0.4 1.1 0.4 0.1 0.3 0.7 0.1 0.1 1.7 0.4 0.6 1.2 1.0 0.5 0.3 0.7 0.1 0.8 0.1 1.2 0.5 1.6 0.6 0.0 0.6 1.0 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.2 0.2 0.7 0.7 0.0 3.4 1.0 0.4 1.4 0.9 1.5 0.7 5.9 0.5 0.8 1.8 0.5 1.2 0.6 0.7 3.1 0.4 0.4 0.7 0.3 0.3 0.3 0.4 0.4 0.2 0.7 0.6 0.7 3.6 1.3 0.3 0.2 0.3 0.2 3.9 4.3 2.8 3.9 5.0 3.2 5.8 6.4 3.7 4.2 3.0 3.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA028476: AB_10599974, HPA028486: AB_10600206, HPA028563: AB_10602286" "unprognostic (2.64e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (7.34e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (8.08e-2)" "unprognostic (6.51e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.67e-2)" "unprognostic (5.06e-2)" "unprognostic (5.50e-2)" "unprognostic (1.17e-2)" 21.9 21.1 19.2 17.0 20.5 14.2 23.5 20.2 20.7 20.4 19.7 22.8 20.1 19.8 20.5 26.1 19.1 11.8 28.7 20.1 19.5 21.7 32.8 17.7 22.8 20.2 20.3 15.5 18.9 18.0 15.1 14.3 20.6 24.3 18.9 9.8 21.0 13.7 34.1 32.9 24.9 17.7 19.6 30.1 22.0 19.0 20.6 16.0 22.5 32.0 23.0 22.6 21.1 21.0 33.4 52.4 32.8 56.1 27.9 20.5 62.1 24.7 20.5 35.2 30.2 46.9 40.1 38.5 48.8 23.0 18.3 42.6 63.4 51.3 23.0 40.6 47.5 31.4 42.8 33.7 38.1 46.0 39.1 29.5 65.9 40.2 42.8 17.0 41.5 40.4 51.4 30.3 30.2 71.8 31.9 32.0 71.7 72.2 53.8 52.8 16.2 88.7 33.9 45.8 54.9 75.6 38.7 86.2 50.0 63.0 74.0 68.6 26.4 21.9 30.1 28.6 39.6 47.5 63.7 66.9 26.4 36.8 36.1 29.8 35.3 23.7 34.5 33.0 38.9 39.0 31.9 33.8 37.7 34.2 29.1 28.9 7.8 26.1 41.4 38.3 37.9 37.6 19.2 20.5 20.2 20.7 20.1 19.5 20.2 20.3 20.6 19.6 20.6 21.0 12.2 9.6 10.6 9.8 19.3 26.5 18.1 37.1 23.3 15.7 16.4 15.9 39.4 20.0 22.6 25.8 6.2 42.5 16.9 22.1 31.3 24.4 25.3 15.4 12.0 14.1 12.0 19.0 8.2 28.2 42.6 12.1 25.0 12.6 8.8 21.2 11.7 27.0 27.6 15.2 6.3 20.8 28.5 18.1 11.1 77.6 10.2 14.8 14.2 5.6 34.7 23.3 32.0 4.5 8.2 25.4 14.9 9.8 18.3 26.1 30.3 32.9 19.3 17.2 6.6 9.7 18.3 22.9 20.6 25.7 27.6 36.0 20.2 23.1 25.4 20.0 FLCN "BHD, DENND8B, MGC17998, MGC23445" ENSG00000154803 Folliculin Q8NFG4 17 17212212-17237188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 79.2;Erythroid cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015158, HPA028760" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Plasma membrane" "CAB015158: AB_2231645, HPA028760: AB_10601323" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (1.53e-2)" "unprognostic (1.74e-1)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (3.90e-1)" "prognostic favorable (4.49e-4)" "unprognostic (6.45e-3)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.65e-1)" 21.8 19.0 19.0 10.7 25.9 17.7 18.9 27.3 31.6 42.5 18.3 43.7 23.3 37.0 14.5 13.8 25.2 17.0 29.2 31.9 14.0 15.3 28.9 26.8 12.4 21.3 15.2 35.3 15.2 13.1 28.6 13.1 22.0 27.1 10.2 7.2 16.4 13.7 42.7 19.3 26.8 14.5 14.0 29.2 22.4 21.0 19.3 8.6 23.8 18.4 8.0 28.2 25.5 28.3 12.0 30.4 11.5 14.9 36.4 20.6 15.8 11.8 19.1 18.0 24.3 24.3 10.4 6.3 13.8 14.0 40.2 14.4 14.0 7.3 9.3 10.9 12.2 12.4 9.1 13.9 33.6 4.9 33.5 30.3 24.0 27.6 20.8 16.4 14.8 9.2 17.7 16.4 17.6 17.5 8.3 8.4 11.2 17.8 8.1 16.9 52.7 7.3 11.0 14.1 13.6 8.8 11.6 7.5 19.3 70.7 11.1 8.8 15.7 40.6 16.6 56.5 14.1 7.7 7.4 5.7 26.0 10.8 16.6 2.4 2.8 1.6 1.6 3.7 2.2 3.6 1.9 1.4 1.4 3.2 2.1 1.9 6.0 2.8 1.4 1.4 2.9 1.8 19.0 25.9 27.3 31.6 31.9 14.0 21.3 15.2 22.0 14.0 19.3 28.3 8.4 25.6 12.6 17.0 9.2 18.4 12.7 5.7 2.8 20.7 13.2 6.5 23.7 14.3 6.2 7.3 79.2 10.9 5.3 25.0 1.9 12.3 14.5 16.8 11.3 12.5 25.7 81.7 31.3 8.3 7.4 20.6 9.7 15.2 1.3 10.3 27.8 24.1 16.6 47.1 23.7 11.0 16.2 21.6 19.2 20.4 28.0 13.2 10.6 18.7 12.2 13.3 6.2 17.1 32.4 9.8 15.6 20.3 4.4 11.6 36.8 6.1 9.1 18.5 19.7 24.8 11.1 6.3 10.8 5.3 18.2 33.8 10.0 16.3 12.6 13.0 FLNA "ABP-280, FLN, FLN1, OPD1, OPD2" ENSG00000196924 "Filamin A" P21333 X 154348524-154374634 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cilium biogenesis/degradation" Actin-binding "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 1203.7;intestine: 1462.2" "Cell type enhanced" "Detected in many" "Peritubular cells: 500.6;Sertoli cells: 420.7;Smooth muscle cells: 459.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000356, HPA000368, HPA001016, HPA001115, HPA002925" Enhanced Approved Enhanced "Plasma membrane,Actin filaments,Cytosol" NA NA 730000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments, Cytosol" "CAB000356: , HPA000368: AB_2797215, HPA001016: , HPA001115: AB_1078871, HPA002925: AB_1078869" "unprognostic (1.39e-1)" "unprognostic (9.40e-3)" "prognostic unfavorable (7.37e-4)" "unprognostic (3.68e-2)" "unprognostic (2.55e-1)" "unprognostic (6.05e-3)" "unprognostic (5.08e-2)" "unprognostic (1.08e-1)" "unprognostic (6.02e-2)" "unprognostic (1.30e-1)" "unprognostic (3.23e-2)" "unprognostic (9.58e-2)" "prognostic unfavorable (1.54e-6)" "unprognostic (5.49e-3)" "unprognostic (1.78e-1)" "unprognostic (1.62e-1)" "prognostic unfavorable (3.88e-4)" 267.4 55.9 14.4 223.2 18.5 157.9 164.2 15.2 43.0 392.1 54.7 1462.2 89.9 1203.7 35.5 454.7 609.4 137.9 108.4 14.8 23.0 70.5 21.2 238.9 65.0 39.9 19.9 236.7 50.5 13.4 30.5 79.2 24.4 369.2 86.9 9.0 80.3 617.2 49.7 124.7 354.6 706.6 21.1 102.7 508.0 33.7 34.0 48.1 85.6 31.2 38.1 1053.9 286.4 21.5 947.2 719.2 246.7 316.1 209.8 278.4 400.9 614.0 680.1 552.5 489.8 469.2 169.4 80.5 1551.4 966.4 970.1 528.3 224.0 538.1 152.7 333.6 77.8 262.2 914.9 159.7 375.9 309.3 324.9 266.1 126.1 825.5 327.0 533.8 417.1 94.9 74.7 538.7 401.3 210.7 148.5 93.1 258.3 97.9 470.9 147.8 221.2 71.6 197.2 193.4 52.9 119.7 515.8 80.2 381.1 187.3 79.1 96.3 1016.6 625.2 586.8 640.0 1147.1 333.7 212.8 162.3 580.3 202.4 638.7 7.6 24.9 11.8 32.6 23.1 21.2 10.2 15.6 29.2 22.4 4.6 6.0 14.3 3.6 10.5 34.2 2.7 20.7 56.2 14.4 18.5 15.2 43.0 14.8 23.0 39.9 19.9 24.4 21.1 34.0 21.5 105.1 57.7 38.7 30.0 76.9 124.3 85.9 127.8 85.4 3.5 40.9 153.5 34.5 38.6 26.1 35.0 0.0 24.6 257.7 2.6 1.9 272.0 2.1 33.8 186.3 107.0 1.8 39.7 11.8 133.1 90.9 137.9 13.3 55.8 26.0 334.5 81.8 4.3 120.3 11.8 8.6 2.5 22.4 141.0 263.0 13.7 122.4 227.7 88.9 30.9 207.9 39.4 270.8 8.0 2.6 347.4 1.5 500.6 98.7 96.1 1.9 3.0 9.1 4.3 420.7 118.3 459.3 4.1 8.9 48.8 73.6 20.0 172.3 134.7 3.3 35.3 FLNB "ABP-278, FH1, FLN1L, LRS1, TABP, TAP" ENSG00000136068 "Filamin B" O75369 3 58008400-58172251 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Differentiation, Myogenesis" "Actin-binding, Developmental protein" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 344.9;Pancreatic endocrine cells: 385.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 17.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 523.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004747, HPA004886, CAB019322" Enhanced Supported "Golgi apparatus,Plasma membrane,Actin filaments,Cytosol" NA NA 20000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 1: Thyroid gland - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Actin filaments, Cytosol" "CAB019322: , HPA004747: AB_1848599, HPA004886: AB_1848600" "unprognostic (1.29e-2)" "unprognostic (1.08e-2)" "unprognostic (5.97e-2)" "unprognostic (6.86e-2)" "unprognostic (1.26e-1)" "unprognostic (2.05e-1)" "unprognostic (6.52e-2)" "unprognostic (1.72e-1)" "unprognostic (9.61e-2)" "unprognostic (5.02e-3)" "prognostic unfavorable (8.45e-5)" "unprognostic (9.23e-2)" "prognostic favorable (3.45e-6)" "unprognostic (4.38e-2)" "unprognostic (1.36e-1)" "unprognostic (6.65e-3)" "unprognostic (2.33e-1)" 74.6 63.1 42.8 22.3 51.3 7.4 90.4 50.9 52.4 45.5 57.1 122.2 52.8 75.5 120.3 57.7 75.9 19.6 47.2 40.1 41.6 96.7 71.5 49.9 24.4 54.4 52.3 68.9 83.2 59.9 38.1 48.0 52.6 124.4 74.4 10.2 64.0 51.4 16.3 91.3 92.7 36.2 48.1 55.3 70.2 30.4 50.0 74.8 91.1 17.8 23.8 114.7 58.6 58.3 134.4 225.0 22.3 32.9 14.8 25.0 385.7 49.0 39.3 106.6 108.4 227.1 223.1 21.9 18.1 172.9 172.8 215.9 42.1 311.5 103.0 121.6 20.8 18.4 192.7 110.5 107.8 16.2 63.1 40.2 132.1 148.5 448.3 125.2 365.4 94.7 30.9 6.6 67.0 29.2 49.3 38.5 34.5 146.6 192.1 21.6 5.8 18.7 143.8 224.6 24.7 23.1 247.3 132.6 27.4 160.9 110.3 44.6 523.3 27.8 84.5 334.1 175.6 4.8 1.7 17.0 102.2 29.2 29.9 10.1 0.3 5.0 0.5 0.8 2.7 4.1 1.7 0.8 1.4 1.6 5.1 3.8 0.2 7.3 1.5 17.9 2.0 1.5 42.8 51.3 50.9 52.4 40.1 41.6 54.4 52.3 52.6 48.1 50.0 58.3 133.7 51.3 30.2 3.9 11.0 50.6 42.9 73.2 29.0 3.3 86.6 43.4 10.0 57.2 62.0 47.8 39.6 28.7 36.8 344.9 0.0 93.8 15.6 103.6 24.4 92.9 49.2 10.3 34.1 67.1 207.1 28.8 88.7 133.8 24.7 34.4 151.3 52.0 14.6 1.7 34.3 82.8 38.7 11.3 12.2 22.4 16.1 11.1 5.4 22.5 11.6 9.1 2.1 25.1 40.9 385.7 161.0 27.8 3.4 115.2 157.3 6.5 76.1 10.6 0.0 4.4 25.9 4.4 6.9 46.4 51.7 49.8 9.9 84.6 93.0 88.4 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLOT1 ENSG00000137312 "Flotillin 1" O75955 6 30727709-30742732 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 314.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 423.3;hTERT-RPE1: 242.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001393, CAB007766" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Vesicles, Plasma membrane" "CAB007766: AB_562116, HPA001393: AB_1078892" "unprognostic (2.68e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (5.78e-4)" "unprognostic (1.78e-2)" "unprognostic (2.21e-1)" "unprognostic (3.41e-3)" "unprognostic (2.68e-3)" "unprognostic (1.86e-1)" "unprognostic (2.65e-1)" "prognostic favorable (3.06e-4)" "unprognostic (1.81e-2)" "unprognostic (9.36e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (6.43e-3)" "unprognostic (3.92e-1)" "unprognostic (1.61e-2)" "unprognostic (2.46e-2)" 141.7 239.5 49.3 27.9 54.6 41.7 129.8 49.4 60.9 111.1 56.8 150.3 28.7 108.9 8.4 81.8 95.8 23.1 234.5 55.1 57.9 146.1 127.3 136.8 22.1 50.9 51.5 84.1 88.5 41.4 102.5 35.0 57.4 109.6 17.7 6.3 99.1 45.8 190.0 51.7 87.1 33.0 45.8 129.6 96.9 65.0 53.6 24.9 111.7 83.1 17.0 134.5 96.9 48.8 54.3 18.3 46.4 62.0 49.1 71.0 1.3 59.7 67.5 82.8 79.3 19.4 30.0 13.0 29.0 101.3 423.3 41.8 35.0 20.1 28.6 36.1 1.3 41.1 17.5 19.1 119.2 12.2 67.0 75.4 30.6 40.9 71.3 242.7 65.9 37.9 21.7 52.7 77.9 22.9 38.0 14.5 15.1 29.4 15.7 20.2 48.4 38.0 30.3 13.0 16.4 17.2 33.7 28.7 164.6 30.4 43.8 10.1 44.0 199.5 37.6 20.6 120.6 18.6 19.7 28.8 26.2 42.6 122.7 179.3 76.9 132.0 35.0 38.9 24.1 28.0 21.3 30.4 58.9 23.0 23.7 27.4 314.3 79.9 26.3 59.2 3.9 58.3 49.3 54.6 49.4 60.9 55.1 57.9 50.9 51.5 57.4 45.8 53.6 48.8 175.4 89.8 77.0 26.1 38.1 28.7 111.5 44.9 80.2 14.7 72.1 73.4 90.6 62.9 59.2 84.6 6.2 82.2 57.7 103.2 123.3 77.6 60.2 73.9 50.1 141.6 68.8 41.7 41.3 85.9 70.7 67.6 55.5 75.2 143.3 41.4 154.9 59.7 130.6 20.2 40.2 66.6 57.0 61.3 84.9 144.1 61.8 89.4 71.2 28.1 99.2 64.7 68.0 27.2 22.7 65.7 112.0 38.0 60.4 69.5 89.0 172.1 80.7 18.1 52.6 58.1 65.9 80.2 26.7 63.7 26.9 61.6 51.2 29.1 83.2 99.4 FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" 60.2 46.4 38.4 56.8 38.6 97.1 56.2 28.1 47.6 42.8 45.2 58.9 21.0 39.1 21.2 69.3 46.8 27.0 63.5 41.1 42.5 71.4 98.4 59.5 68.2 45.9 37.1 37.7 38.8 30.0 22.3 58.4 41.3 67.8 27.2 20.3 61.7 51.6 51.6 38.2 53.0 35.3 37.5 122.7 44.6 10.4 47.1 47.8 39.6 44.1 63.6 78.8 49.6 36.1 55.5 90.8 69.6 60.2 33.6 44.2 76.6 42.5 57.9 60.9 71.3 96.0 45.7 76.9 79.3 47.6 42.0 63.3 76.5 69.7 25.9 245.5 91.4 92.7 80.5 70.3 43.6 76.8 15.2 53.3 53.6 49.3 66.9 64.1 97.4 21.8 89.0 65.6 28.9 83.5 21.2 54.0 61.4 48.6 24.6 32.6 70.6 189.3 92.0 166.9 61.9 103.3 99.8 69.6 77.5 66.7 72.3 136.3 81.5 21.4 38.2 35.2 65.0 36.5 68.2 39.5 59.9 72.3 40.7 171.9 106.0 213.2 98.8 96.6 72.6 98.5 74.6 84.5 144.3 118.1 55.3 69.0 415.2 78.5 110.2 38.8 97.6 143.2 38.4 38.6 28.1 47.6 41.1 42.5 45.9 37.1 41.3 37.5 47.1 36.1 34.2 22.4 21.9 12.7 46.8 12.6 27.1 20.6 29.6 6.9 24.9 30.1 32.9 22.8 16.5 20.2 10.4 96.6 20.5 29.0 15.6 39.3 13.0 25.8 13.2 37.0 25.8 49.2 17.0 31.1 68.9 14.8 23.0 27.6 6.3 15.6 48.9 45.1 44.4 5.0 19.2 25.9 10.2 43.3 22.6 42.3 10.8 31.1 8.8 22.5 75.2 10.7 35.0 16.1 11.0 32.2 16.5 8.6 27.8 14.8 14.8 26.7 19.1 12.4 19.7 7.1 13.4 1.6 6.9 42.4 9.2 37.1 32.5 4.2 32.0 26.7 FLRT3 ENSG00000125848 "Fibronectin leucine rich transmembrane protein 3" Q9NZU0 20 14322985-14337614 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Developmental protein" "Disease variant, Hypogonadotropic hypogonadism, Kallmann syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 23.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0;Alveolar cells type 2: 156.5;Basal prostatic cells: 168.3;Club cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 27.5;hTCEpi: 51.3;RPTEC TERT1: 17.3;WM-115: 62.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056033 Enhanced Supported "Plasma membrane,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA 1100000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA056033: AB_2683016" "unprognostic (2.14e-1)" "unprognostic (2.57e-1)" "unprognostic (2.98e-1)" "unprognostic (1.14e-3)" "unprognostic (2.30e-1)" "unprognostic (6.00e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.85e-5)" "unprognostic (1.24e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.05e-1)" "prognostic favorable (1.49e-7)" "unprognostic (1.54e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-3)" "unprognostic (3.65e-1)" 5.0 3.7 2.3 0.8 3.0 0.0 2.3 6.4 5.3 3.2 0.9 1.6 11.8 2.3 3.1 1.6 2.4 5.0 0.6 5.3 1.3 23.2 7.0 17.7 0.1 0.0 1.3 10.6 1.2 8.2 1.0 1.8 0.8 8.2 0.8 1.6 1.2 14.0 2.0 6.3 2.3 1.4 0.6 0.7 9.7 1.2 2.3 7.3 5.2 0.7 0.3 7.9 2.1 1.8 0.0 12.2 27.5 0.0 0.0 0.0 0.0 2.7 0.8 0.1 0.0 15.3 5.6 0.0 0.9 0.6 0.0 8.0 0.0 8.3 0.1 0.0 1.8 0.0 0.4 0.3 2.4 0.0 0.0 4.6 51.3 0.0 9.7 0.0 0.1 0.2 0.0 0.2 5.3 0.4 3.7 0.0 8.9 6.2 0.1 0.1 0.2 0.0 17.3 3.6 0.5 5.7 0.0 0.0 9.2 15.5 0.5 0.0 0.0 0.0 1.8 0.1 0.7 0.0 0.0 0.0 0.2 0.0 62.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.0 6.4 5.3 5.3 1.3 0.0 1.3 0.8 0.6 2.3 1.8 0.3 218.0 156.5 2.3 0.5 8.7 168.3 26.1 55.8 23.9 4.4 6.5 1.2 24.3 73.1 22.0 6.2 0.5 0.0 2.2 13.7 23.6 0.2 0.7 1.7 1.9 11.3 0.0 27.2 14.9 0.0 8.7 37.8 0.7 5.1 5.0 2.9 8.5 0.2 6.7 39.3 2.5 2.0 0.3 0.7 0.5 3.7 1.3 5.4 1.9 1.6 0.6 0.0 26.2 3.9 10.0 3.0 0.4 0.1 24.9 3.5 49.2 13.4 3.3 0.0 25.0 1.8 0.0 0.1 5.9 16.6 0.0 0.8 1.4 1.5 18.3 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FLT4 "PCL, VEGFR-3, VEGFR3" ENSG00000037280 "Fms related receptor tyrosine kinase 4" P35916 5 180601506-180649624 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 7 "Adipocytes: 27.4;Endothelial cells: 27.1;Extravillous trophoblasts: 37.1;Hepatic stellate cells: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 31 "T-cells: 3.8" "Cell line enhanced" "Detected in some" "AN3-CA: 10.1;BEWO: 12.4;HEK 293: 15.6;HL-60: 9.5;HUVEC TERT2: 9.9;JURKAT: 12.3;T-47d: 14.6;TIME: 15.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB000099, HPA046519, HPA067906, HPA074389" Approved Supported "Nuclear speckles,Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 20000000 290000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 6: T47d - Mammary gland" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nuclear speckles, Plasma membrane" "Cell Junctions" "CAB000099: , HPA046519: AB_2732527, HPA067906: AB_2732775, HPA074389: " "unprognostic (7.35e-2)" "unprognostic (1.63e-1)" "unprognostic (9.45e-3)" "unprognostic (3.81e-1)" "unprognostic (9.26e-2)" "unprognostic (3.20e-3)" "unprognostic (1.13e-2)" "unprognostic (1.80e-2)" "unprognostic (2.19e-1)" "unprognostic (1.70e-1)" "unprognostic (2.13e-2)" "unprognostic (3.69e-1)" "unprognostic (1.88e-2)" "unprognostic (9.41e-3)" "unprognostic (1.83e-1)" "unprognostic (8.26e-2)" "unprognostic (1.32e-1)" 17.2 11.3 3.5 4.7 4.6 0.8 14.7 2.6 3.4 9.0 2.6 4.9 2.8 8.0 3.0 4.4 9.8 3.8 9.7 5.1 2.6 20.1 6.2 16.9 5.5 3.4 3.0 4.5 2.0 2.3 7.8 6.4 3.6 5.6 1.3 0.3 2.0 2.5 4.7 4.0 7.2 4.1 2.8 17.6 3.5 3.1 4.2 1.0 25.7 4.1 1.4 5.6 5.5 2.7 0.1 2.5 3.2 10.1 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.4 0.3 0.3 0.9 0.1 0.6 0.4 3.4 0.2 0.3 0.1 15.6 1.2 0.5 0.5 0.1 9.5 0.3 0.2 0.1 0.2 0.4 0.3 9.9 12.3 0.4 0.4 2.1 5.6 0.1 0.5 7.0 0.3 0.6 8.2 0.1 0.1 0.1 0.3 0.3 1.1 0.1 0.2 0.1 3.1 14.6 0.3 15.7 0.2 6.9 0.2 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.0 0.5 0.0 3.8 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 3.5 4.6 2.6 3.4 5.1 2.6 3.4 3.0 3.6 2.8 4.2 2.7 27.4 0.0 1.7 0.7 0.7 0.9 0.2 0.0 1.2 0.2 1.4 1.4 4.5 0.0 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.1 27.1 0.0 0.0 0.2 0.0 37.1 0.8 0.0 0.1 2.5 2.4 64.6 0.6 1.2 0.0 0.1 0.0 0.0 3.3 0.8 0.7 0.3 0.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.2 0.0 0.7 0.7 0.1 5.2 0.1 1.1 1.0 1.8 0.2 0.0 0.1 FLVCR1 "AXPC1, FLVCR, MFSD7B, PCA, SLC49A1" ENSG00000162769 "FLVCR heme transporter 1" Q9Y5Y0 1 212858275-212899363 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Erythrocyte maturation, Transport" Receptor "Disease variant, Neurodegeneration, Neuropathy, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 19.4" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 73.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "NTERA-2: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046646 Approved Approved "Cell Junctions" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 45: Enterocytes - Digestion" "Cell Junctions" "HPA046646: AB_2679735" "unprognostic (2.09e-1)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (1.01e-1)" "unprognostic (2.83e-2)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.52e-5)" "unprognostic (1.03e-1)" "unprognostic (1.21e-1)" "unprognostic (3.88e-2)" "prognostic favorable (3.50e-4)" "unprognostic (1.89e-1)" "prognostic unfavorable (1.06e-5)" "unprognostic (7.15e-2)" "unprognostic (2.25e-1)" "unprognostic (3.91e-2)" "unprognostic (7.29e-3)" 2.1 2.4 3.4 3.1 2.8 6.2 3.1 5.0 3.7 2.9 2.7 3.4 9.7 2.5 4.9 2.1 2.4 2.0 1.6 3.2 4.4 2.4 1.8 2.4 2.9 4.5 4.1 2.4 2.6 3.6 6.9 2.4 5.3 3.4 2.8 7.0 1.9 1.8 1.0 2.9 19.4 1.7 2.5 2.6 4.8 2.8 4.3 2.6 2.2 0.6 2.2 2.3 2.3 4.2 8.4 11.0 16.8 5.1 2.8 3.4 31.3 2.4 1.8 4.8 2.9 16.1 15.2 9.1 4.4 1.7 10.2 12.5 18.2 5.4 4.7 5.4 8.0 5.4 10.4 14.9 3.2 14.5 8.4 2.7 3.5 5.2 6.6 2.5 3.8 6.4 14.7 7.4 3.2 3.2 4.1 7.2 55.3 11.1 7.7 9.0 15.4 10.6 6.0 8.0 18.1 12.7 11.2 11.1 10.4 13.8 18.2 6.7 2.2 2.3 5.6 7.7 11.2 4.6 9.9 10.8 3.5 8.3 2.9 0.5 0.2 1.5 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.3 0.3 0.7 0.2 0.2 0.4 0.4 0.0 3.4 2.8 5.0 3.7 3.2 4.4 4.5 4.1 5.3 2.5 4.3 4.2 6.7 12.8 16.0 12.4 8.3 14.3 8.8 6.9 9.6 24.0 10.3 9.5 4.1 14.3 12.1 20.2 35.5 3.9 6.8 13.7 1.9 5.5 4.7 7.0 7.8 9.3 32.4 9.5 28.8 13.4 6.7 8.8 17.3 7.6 7.0 20.1 10.0 9.2 6.5 16.8 39.4 10.6 10.2 10.1 9.6 6.8 6.2 9.0 5.4 9.4 10.5 5.8 4.1 24.1 28.7 8.9 12.0 2.6 6.5 11.9 73.7 4.6 10.1 31.8 6.6 18.0 7.2 10.4 6.8 7.0 9.2 2.5 8.3 5.1 8.2 4.3 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FMNL2 "FHOD2, KIAA1902" ENSG00000157827 "Formin like 2" Q96PY5 2 152335174-152649826 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 223.5" "Cell type enhanced" "Detected in many" "Astrocytes: 668.0;Excitatory neurons: 574.9;Inhibitory neurons: 321.9;Oligodendrocyte precursor cells: 371.0;Oligodendrocytes: 2442.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.4" "Lineage enriched" "Detected in single" 5 "monocytes: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 191.4;hTERT-HME1: 123.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005464 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Golgi apparatus, Plasma membrane" "HPA005464: AB_1848965" "unprognostic (1.19e-1)" "unprognostic (6.92e-2)" "unprognostic (8.75e-3)" "unprognostic (3.06e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "prognostic unfavorable (9.04e-4)" "unprognostic (1.34e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (2.54e-1)" "unprognostic (4.66e-2)" "unprognostic (5.68e-2)" "unprognostic (1.05e-1)" "unprognostic (2.58e-1)" "unprognostic (3.73e-2)" "unprognostic (1.58e-1)" 26.4 25.2 88.9 11.1 152.3 0.7 20.8 135.2 119.3 18.1 73.6 15.2 8.9 20.7 14.9 8.5 15.3 16.8 12.0 92.9 102.6 22.2 8.1 32.2 14.2 172.3 136.3 54.0 18.1 23.1 28.4 58.2 165.5 15.2 12.3 10.6 32.1 11.7 24.1 11.3 11.6 16.3 121.6 19.8 17.3 9.0 128.5 14.8 33.1 19.3 8.4 19.3 18.3 223.5 14.5 15.1 45.9 25.5 54.5 58.3 191.4 14.4 29.4 24.9 34.8 16.3 0.9 0.3 29.8 12.6 53.7 16.2 22.4 45.8 39.6 0.1 23.4 0.2 10.0 70.2 15.7 4.0 0.8 38.4 27.8 48.2 123.5 48.3 44.7 6.6 0.6 0.3 13.9 4.0 0.8 4.5 29.5 12.4 30.0 25.9 9.9 20.9 72.9 9.9 46.6 38.0 12.2 4.5 51.4 38.7 1.1 1.5 49.9 37.4 1.0 12.7 25.0 1.3 0.5 0.1 34.7 3.3 77.8 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.2 0.0 0.0 88.9 152.3 135.2 119.3 92.9 102.6 172.3 136.3 165.5 121.6 128.5 223.5 21.5 25.6 25.9 668.0 2.7 26.4 23.0 14.0 19.4 23.8 11.4 10.0 3.8 1.5 16.4 11.0 0.0 36.1 4.5 2.6 13.7 20.4 24.5 14.1 10.8 29.1 8.3 0.4 574.9 6.9 17.8 36.2 8.2 27.0 1.3 36.0 20.0 1.3 40.6 0.0 321.9 3.3 10.2 64.8 53.0 10.5 35.1 31.5 7.2 245.4 4.4 3.9 1.0 371.0 2442.0 10.0 2.1 41.3 5.6 33.5 0.7 8.9 8.5 2.0 6.6 18.7 13.2 6.7 8.0 6.3 16.9 27.0 2.1 13.0 6.1 13.2 FMNL3 "DKFZp762B245, MGC45819, WBP3" ENSG00000161791 "Formin like 3" Q8IVF7 12 49636499-49708165 "Predicted intracellular proteins" Angiogenesis "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 35.8;Cone photoreceptor cells: 39.6;dendritic cells: 48.6;Microglial cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 47.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002552, HPA023201" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" Cytosol "HPA002552: AB_1078862, HPA023201: AB_1848575" "unprognostic (2.97e-1)" "unprognostic (2.77e-3)" "unprognostic (4.97e-3)" "unprognostic (7.19e-2)" "unprognostic (5.42e-2)" "unprognostic (2.33e-3)" "unprognostic (5.37e-3)" "unprognostic (1.52e-2)" "unprognostic (2.83e-1)" "unprognostic (1.54e-1)" "unprognostic (6.67e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (3.58e-5)" "unprognostic (1.04e-1)" "unprognostic (2.31e-1)" "unprognostic (2.03e-1)" "unprognostic (2.69e-2)" 12.2 5.7 13.7 20.5 13.2 5.2 10.6 13.0 11.2 9.6 3.0 8.0 5.7 11.2 19.2 4.5 6.9 11.1 12.6 11.0 12.6 9.3 2.7 17.4 23.5 21.7 14.6 16.1 3.2 3.6 4.1 14.0 18.2 6.0 5.6 2.7 4.6 4.4 5.6 4.4 10.2 11.5 17.7 13.4 6.6 10.1 20.4 20.1 13.4 6.7 28.3 8.6 6.3 20.4 8.6 2.5 18.4 6.1 5.0 20.1 0.2 10.4 21.0 13.8 12.1 9.7 2.3 18.2 19.5 12.4 15.2 0.4 9.5 4.3 12.6 16.2 3.6 20.1 2.9 0.5 8.8 4.0 25.1 12.7 0.7 21.7 9.1 41.2 37.1 9.0 4.6 13.0 20.5 6.3 16.6 6.0 6.0 0.9 5.5 7.9 23.0 2.8 13.1 1.3 3.0 8.6 6.0 0.8 11.8 9.3 1.5 5.9 47.2 34.2 11.8 0.6 18.2 6.7 0.4 9.8 21.3 12.4 14.7 3.0 0.1 0.8 0.8 0.4 0.4 0.2 0.3 0.5 0.2 1.1 0.4 0.5 0.0 0.6 0.3 5.1 0.1 0.5 13.7 13.2 13.0 11.2 11.0 12.6 21.7 14.6 18.2 17.7 20.4 20.4 35.8 3.2 3.4 6.8 17.5 1.7 0.7 0.4 2.2 11.3 1.3 2.3 3.3 0.0 1.4 1.8 39.6 2.1 48.6 0.1 0.0 0.3 2.0 0.7 2.6 29.7 0.0 1.7 16.0 0.6 0.8 7.1 1.5 2.0 27.8 5.4 15.7 0.8 11.1 3.3 6.5 0.8 0.0 6.9 9.0 4.6 3.7 17.7 5.4 119.0 22.9 0.5 16.5 27.6 5.5 0.8 0.1 6.4 1.8 0.8 0.0 0.2 0.2 2.0 13.1 15.5 10.3 5.9 7.5 0.4 1.4 2.5 13.6 2.6 0.1 0.4 FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043194 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 317.7;Langerhans cells: 402.9;monocytes: 433.2;Oligodendrocytes: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 137.7;JURKAT: 143.2;MOLT-4: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Vesicles "HPA019635: AB_2732423, HPA019691: AB_2670231, HPA022119: AB_2670897, HPA067742: " "unprognostic (2.86e-1)" "unprognostic (2.59e-3)" "unprognostic (1.22e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.30e-3)" "unprognostic (9.10e-2)" "unprognostic (2.90e-1)" "unprognostic (6.17e-2)" "unprognostic (9.26e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (8.45e-5)" "unprognostic (6.84e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" 21.8 11.9 51.2 57.8 73.7 40.6 16.4 77.4 53.4 32.5 22.2 107.3 15.0 50.0 17.0 39.4 34.8 27.8 15.1 47.0 62.5 16.4 18.4 25.4 78.1 67.6 69.1 22.1 8.1 10.7 17.7 16.3 65.8 41.4 29.6 12.6 16.3 44.1 24.1 25.9 37.6 46.8 55.9 60.9 29.6 17.3 69.9 111.0 33.4 13.2 74.3 68.4 26.8 86.6 42.5 19.3 34.9 40.8 21.0 25.8 29.5 23.7 20.2 17.6 14.7 20.3 16.2 82.9 20.4 44.5 20.8 20.7 33.0 21.6 17.6 137.7 9.8 22.8 22.8 13.8 35.8 62.3 75.1 18.7 9.3 32.6 19.5 25.6 26.1 143.2 5.4 1.1 16.4 34.0 140.1 60.8 27.5 5.7 32.6 31.9 28.3 24.1 22.1 23.0 5.5 17.6 43.3 42.9 16.5 33.3 30.0 28.3 31.9 16.6 20.7 30.5 15.0 16.4 64.4 3.8 20.0 42.2 25.2 13.2 5.1 9.6 10.8 5.6 9.3 12.7 9.7 10.3 5.8 7.7 8.9 8.6 9.3 6.0 6.5 6.9 10.9 4.5 51.2 73.7 77.4 53.4 47.0 62.5 67.6 69.1 65.8 55.9 69.9 86.6 27.2 35.3 25.2 317.7 180.4 33.1 21.3 12.8 21.6 20.2 42.5 24.6 14.8 15.7 29.8 22.0 52.1 18.6 217.2 28.3 19.6 22.6 1.7 46.2 38.8 38.3 18.1 31.3 65.6 17.3 24.5 38.8 26.5 78.7 80.4 9.2 71.0 18.4 43.6 28.6 107.8 8.7 20.3 221.2 402.9 5.5 46.6 131.1 76.5 95.5 433.2 42.8 223.5 69.4 522.1 21.8 19.8 51.6 147.9 67.8 0.2 15.0 42.3 29.5 59.2 19.9 41.0 26.5 45.4 26.7 41.1 63.9 233.7 7.1 16.2 42.3 FOXA2 HNF3B ENSG00000125798 "Forkhead box A2" Q9Y261 20 22580998-22585455 "Cancer-related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "liver: 36.2;pancreas: 26.6;stomach 1: 31.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 96.1;Alveolar cells type 2: 78.0;Cholangiocytes: 47.1;Exocrine glandular cells: 37.0;Gastric mucus-secreting cells: 37.8;Hepatocytes: 63.7;Intestinal goblet cells: 87.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 5 "midbrain: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 17.5;HBEC3-KT: 19.3;Hep G2: 28.8;hTERT-HME1: 12.6;OE19: 22.7;PC-3: 24.7;SCLC-21H: 42.7" "Not detected" "Not detected" "Region enriched" "Detected in single" 9 "midbrain: 3.9" "CAB001388, HPA066846" Enhanced Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Cell Junctions" "CAB001388: AB_2262810, HPA066846: AB_2685736" "unprognostic (1.19e-1)" "unprognostic (1.99e-1)" "prognostic favorable (7.57e-6)" "unprognostic (6.82e-2)" "unprognostic (1.50e-6)" "unprognostic (1.38e-1)" "unprognostic (8.17e-2)" "prognostic favorable (6.28e-4)" "prognostic favorable (2.34e-4)" "unprognostic (3.18e-1)" "unprognostic (2.55e-15)" "unprognostic (2.50e-2)" "unprognostic (1.68e-1)" "unprognostic (7.12e-2)" "unprognostic (3.93e-3)" 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 14.2 0.0 7.3 3.7 2.1 0.0 0.1 4.3 4.0 0.0 0.0 0.0 0.2 36.2 13.7 0.0 0.0 2.5 0.0 26.6 0.0 0.0 0.0 0.0 0.3 9.5 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 31.1 0.4 0.5 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 0.6 0.0 0.3 0.0 0.1 0.0 0.0 19.3 0.0 0.0 1.2 0.0 0.0 28.8 0.0 0.0 0.0 0.0 10.3 0.0 12.6 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 22.7 24.7 0.0 0.0 0.0 0.8 0.0 42.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.5 0.0 0.0 96.1 78.0 0.0 0.1 0.0 0.8 0.5 0.0 0.0 0.1 0.3 0.3 47.1 12.5 0.0 0.0 0.0 0.0 21.7 0.0 25.6 0.1 30.8 2.6 0.1 28.1 0.0 0.0 37.0 0.0 0.3 37.8 27.1 4.5 0.0 0.7 63.7 0.0 0.0 0.0 87.2 6.1 1.0 0.0 0.1 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 24.4 6.8 0.0 0.2 1.0 1.0 0.0 10.0 0.0 0.0 0.0 0.2 4.1 0.2 0.0 0.0 0.0 1.0 0.0 28.7 0.1 FOXN3 "C14orf116, CHES1" ENSG00000053254 "Forkhead box N3" O00409 14 89124871-89619149 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 517.2;Oligodendrocyte precursor cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 109.2;U-266/84: 112.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059209 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane" "HPA059209: AB_2683949" "unprognostic (1.69e-1)" "unprognostic (6.13e-3)" "unprognostic (2.08e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-2)" "unprognostic (2.03e-1)" "unprognostic (3.03e-1)" "unprognostic (1.34e-2)" "unprognostic (8.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.19e-1)" "prognostic favorable (9.58e-5)" "unprognostic (2.22e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (2.11e-1)" 46.5 27.0 17.8 23.6 17.9 83.7 22.8 76.2 15.1 24.9 33.4 28.8 36.7 26.5 9.2 39.4 23.2 22.9 38.2 12.2 15.8 12.8 30.8 23.9 29.1 20.5 18.3 50.6 24.8 46.9 5.1 22.7 21.5 20.2 21.8 16.5 18.4 22.1 79.6 41.4 35.2 35.1 19.3 21.6 29.0 16.8 21.5 41.6 9.5 72.6 30.9 25.5 20.6 18.3 0.5 7.7 19.7 11.3 78.1 24.8 14.2 15.7 15.4 13.8 22.7 7.8 6.3 24.0 7.8 25.0 9.5 5.6 33.5 22.3 20.4 109.2 6.2 8.3 14.6 25.0 25.3 16.6 14.1 59.4 12.6 1.3 9.4 16.6 30.2 34.1 10.0 69.0 22.9 9.4 32.2 16.6 21.2 14.2 13.8 51.4 67.0 22.8 1.7 26.6 10.7 35.1 23.0 21.9 6.4 64.8 12.8 45.3 55.0 23.5 32.1 23.6 23.6 58.4 112.6 44.6 8.5 28.2 13.8 48.8 23.8 35.8 41.9 25.7 33.3 13.5 27.8 35.9 35.2 16.4 35.8 34.6 9.6 32.2 17.3 7.9 35.9 31.2 17.8 17.9 76.2 15.1 12.2 15.8 20.5 18.3 21.5 19.3 21.5 18.3 108.7 32.1 33.9 229.5 65.4 89.3 22.4 27.4 41.5 123.2 21.0 21.7 103.2 47.1 53.4 9.2 0.0 36.9 105.9 37.2 21.5 11.5 86.2 38.8 36.3 67.3 59.3 52.5 125.6 20.9 21.3 75.2 45.9 36.4 12.7 112.4 55.6 92.9 43.5 79.1 195.2 37.5 30.5 100.3 174.9 38.5 96.3 87.9 32.0 517.2 65.3 38.6 94.7 291.6 143.8 15.5 32.1 85.4 71.3 16.8 77.4 12.2 16.0 9.9 39.5 133.6 57.9 4.3 11.6 51.4 147.6 29.6 85.0 37.2 46.6 29.1 FP565260.3 ENSG00000277117 "ICOS ligand" 21 5022493-5040666 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 17.4" "Cell type enriched" "Detected in single" 6 "monocytes: 4.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 22.8;REH: 18.5;SiHa: 15.6" HPA029179 Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytoplasmic bodies" "HPA029179: AB_2732445" "unprognostic (3.34e-2)" "unprognostic (1.52e-1)" "unprognostic (2.82e-1)" "unprognostic (3.58e-4)" "unprognostic (6.66e-4)" "unprognostic (1.24e-2)" "unprognostic (1.12e-1)" "unprognostic (3.36e-1)" "unprognostic (2.46e-1)" "unprognostic (6.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.43e-2)" "unprognostic (2.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.60e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-1)" 2.8 1.5 6.1 4.7 12.8 3.7 2.4 8.5 8.8 2.8 1.4 2.9 4.8 1.4 0.6 3.4 2.5 3.2 4.2 6.2 7.5 5.0 2.9 1.9 5.5 11.8 10.6 0.3 1.3 0.4 1.2 2.5 11.0 2.1 2.1 0.0 2.2 1.5 0.7 3.8 3.5 1.3 7.0 3.2 4.8 0.8 11.5 1.9 2.1 1.1 6.3 3.0 2.6 17.4 0.3 0.8 0.0 1.5 0.4 0.9 22.8 1.8 1.4 0.2 0.1 5.5 0.9 12.7 3.8 0.1 2.8 4.2 1.4 1.9 0.3 0.4 1.3 0.0 0.6 2.9 0.2 9.7 8.8 0.2 2.2 1.2 1.1 0.0 1.2 0.0 1.5 0.5 0.1 3.1 0.0 5.6 0.9 15.1 7.6 18.5 0.6 12.7 0.5 7.6 1.0 0.0 15.6 12.9 0.3 0.8 4.4 12.5 0.4 0.0 3.4 0.0 0.3 8.9 9.5 8.2 9.0 5.6 2.0 0.0 0.3 0.0 0.0 1.2 0.1 1.2 0.2 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.2 0.4 0.5 0.5 6.1 12.8 8.5 8.8 6.2 7.5 11.8 10.6 11.0 7.0 11.5 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRMD7 "FLJ43346, NYS, NYS1" ENSG00000165694 "FERM domain containing 7" Q6ZUT3 X 132076990-132128020 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" Neurogenesis "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "endometrium 1: 2.9;kidney: 2.7;smooth muscle: 2.2" "Cell type enriched" "Detected in single" 19 "Distal tubular cells: 9.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-87 MG: 1.5" "Region enriched" "Detected in many" 28 "olfactory bulb: 65.7" "Region enriched" "Detected in single" 86 "olfactory bulb: 21.3" HPA000886 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 1: Thyroid gland - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" Nucleoplasm "HPA000886: AB_1079269" "unprognostic (3.08e-2)" "unprognostic (1.27e-1)" "unprognostic (1.36e-1)" "unprognostic (3.07e-1)" "unprognostic (4.02e-2)" "unprognostic (1.64e-2)" "unprognostic (2.28e-1)" "unprognostic (2.18e-2)" "unprognostic (3.84e-1)" "unprognostic (3.54e-2)" "unprognostic (3.00e-1)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 0.0 2.9 0.5 0.0 0.5 0.0 0.1 0.1 0.1 2.7 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.1 0.2 0.0 2.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FRMD8 "FKSG44, FLJ90369, iTAP" ENSG00000126391 "FERM domain containing 8" Q9BZ67 11 65386621-65413525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 83.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 129.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002861 Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 71: Testis - DNA repair" "Cluster 17: WM-115 - Nervous system development" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Centriolar satellite" "Nucleoplasm, Cytosol" "HPA002861: AB_1078878" "unprognostic (1.54e-1)" "unprognostic (4.07e-1)" "unprognostic (6.28e-2)" "unprognostic (1.73e-2)" "unprognostic (1.03e-1)" "unprognostic (1.17e-1)" "prognostic unfavorable (9.94e-5)" "unprognostic (9.12e-3)" "unprognostic (1.51e-2)" "unprognostic (6.36e-3)" "unprognostic (1.90e-2)" "unprognostic (6.41e-3)" "unprognostic (4.19e-3)" "unprognostic (1.47e-2)" "unprognostic (7.36e-3)" "unprognostic (3.34e-1)" "unprognostic (2.91e-2)" 19.8 17.5 9.6 11.8 11.0 13.0 19.7 12.2 14.5 20.8 9.1 15.0 11.7 14.6 5.3 37.3 15.8 11.6 17.1 13.1 7.9 19.7 13.4 23.5 15.6 12.9 11.3 12.2 23.0 4.0 11.6 10.4 11.4 15.8 6.7 1.7 18.0 6.5 14.8 34.0 23.8 6.6 9.5 40.8 13.4 18.0 11.5 11.1 17.8 5.1 13.6 14.6 26.4 16.2 17.8 22.1 8.7 20.4 23.0 12.0 15.6 20.1 18.1 16.7 12.7 21.2 28.5 21.9 41.9 27.6 11.6 30.3 11.3 16.9 7.0 38.8 10.6 29.9 21.5 11.7 12.4 16.9 44.8 14.9 13.2 15.7 8.2 8.9 26.6 23.2 25.5 23.5 18.3 23.9 26.6 24.6 10.2 13.0 28.7 33.7 16.6 25.2 13.5 21.8 18.9 14.0 15.0 60.1 47.7 7.7 22.0 13.7 23.6 18.4 19.7 26.1 12.3 41.0 22.5 20.4 16.0 10.7 129.8 1.1 12.4 17.7 13.1 13.2 14.1 12.5 9.6 16.7 11.3 9.6 8.8 9.8 23.0 8.2 19.6 13.4 10.8 12.3 9.6 11.0 12.2 14.5 13.1 7.9 12.9 11.3 11.4 9.5 11.5 16.2 30.3 3.2 5.8 2.0 20.5 54.3 22.5 17.7 6.2 5.4 15.4 12.6 7.4 12.8 13.8 12.9 0.0 6.4 25.8 29.3 7.9 21.0 22.3 20.1 12.1 24.8 13.1 24.0 13.4 29.1 15.5 13.0 10.7 23.1 14.0 27.3 37.5 11.0 16.0 5.0 4.9 20.5 8.2 20.2 68.7 4.6 6.2 18.7 19.6 10.3 21.6 4.3 18.6 5.0 10.3 33.8 14.0 7.2 11.9 28.1 32.8 4.6 14.3 4.5 6.6 11.4 14.4 5.3 9.6 24.9 83.5 11.4 21.9 35.2 14.6 35.7 FRS2 "FRS2A, FRS2alpha, SNT-1, SNT1" ENSG00000166225 "Fibroblast growth factor receptor substrate 2" Q8WU20 12 69470349-69579793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 104.5;Oligodendrocyte precursor cells: 76.9;Oligodendrocytes: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038323, HPA073385" Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cell Junctions" "HPA038323: , HPA073385: " "unprognostic (9.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (1.28e-1)" "unprognostic (8.50e-2)" "unprognostic (9.29e-2)" "unprognostic (1.51e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "unprognostic (8.97e-2)" "unprognostic (2.34e-2)" "unprognostic (5.70e-3)" "unprognostic (3.80e-2)" "unprognostic (8.22e-2)" "unprognostic (6.66e-2)" 9.9 8.1 13.4 5.4 18.1 27.0 13.2 22.4 16.2 11.9 9.2 8.4 6.0 12.3 13.6 8.6 9.5 11.5 7.8 13.7 15.8 8.2 11.9 8.5 6.1 15.6 13.2 14.9 6.0 12.2 4.7 10.8 15.2 8.0 8.5 10.2 7.8 7.1 7.2 8.3 7.6 11.8 19.2 6.1 7.6 9.2 13.4 9.4 12.8 8.8 7.3 7.9 6.9 27.1 15.1 12.4 21.9 9.7 12.2 13.6 38.9 16.5 17.8 14.8 11.8 25.1 6.4 6.8 10.2 21.5 7.7 13.2 11.6 17.7 18.6 11.7 9.2 12.2 9.9 7.9 11.1 10.6 8.8 13.0 20.4 17.9 13.1 17.8 7.3 7.8 8.7 15.2 12.8 19.3 8.6 4.0 24.4 7.9 9.7 7.5 18.8 5.6 11.3 36.5 10.6 20.6 25.4 10.7 15.5 27.1 31.0 5.9 13.1 11.7 13.0 15.3 13.0 13.2 22.4 6.3 8.5 5.9 10.7 0.5 4.2 2.2 2.6 3.8 2.8 2.8 2.6 2.2 2.9 6.0 5.0 2.9 4.3 2.7 7.4 2.6 1.6 2.0 13.4 18.1 22.4 16.2 13.7 15.8 15.6 13.2 15.2 19.2 13.4 27.1 12.8 6.4 12.7 104.5 13.3 20.3 8.6 9.3 30.7 11.9 29.1 20.6 23.2 5.7 15.0 11.0 16.7 7.9 8.7 6.9 3.9 7.8 5.9 16.3 27.5 10.1 10.2 8.6 64.8 7.2 11.6 20.8 13.7 25.0 13.4 13.0 9.3 15.3 6.9 6.7 68.1 9.4 4.1 10.7 11.8 9.9 19.0 9.9 7.2 43.1 11.6 18.2 6.2 76.9 89.5 12.3 6.0 13.2 11.4 13.1 7.4 7.3 11.0 11.4 6.6 18.5 21.9 11.5 11.7 19.6 12.6 6.3 10.3 18.2 8.0 12.5 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FSD1L "CCDC10, CSDUFD1, FSD1CL, FSD1NL" ENSG00000106701 "Fibronectin type III and SPRY domain containing 1 like" Q9BXM9 9 105447796-105552433 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 43.2" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 423.3;Early spermatids: 97.2;Excitatory neurons: 79.0;Rod photoreceptor cells: 121.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035138 Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 77: Retina - Visual perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA035138: AB_10601324" "unprognostic (9.28e-2)" "unprognostic (4.04e-3)" "unprognostic (1.73e-1)" "unprognostic (1.88e-3)" "unprognostic (3.93e-2)" "unprognostic (1.82e-2)" "unprognostic (3.17e-5)" "unprognostic (4.20e-2)" "unprognostic (5.65e-2)" "unprognostic (9.64e-3)" "unprognostic (2.66e-3)" "unprognostic (3.32e-2)" "unprognostic (8.28e-2)" "unprognostic (2.92e-1)" "unprognostic (1.87e-1)" "unprognostic (8.07e-2)" "unprognostic (1.22e-3)" 1.2 3.5 8.4 2.1 9.4 2.4 1.6 7.8 10.0 1.7 6.3 2.6 4.5 2.1 3.3 0.9 7.1 1.4 4.1 8.9 12.3 2.1 0.7 2.2 1.4 13.2 11.4 1.4 1.4 2.0 3.3 0.9 11.5 1.6 2.4 43.2 1.1 1.6 7.3 1.1 3.7 1.5 11.7 1.4 2.2 5.8 12.5 1.6 2.0 13.3 1.5 1.1 0.9 12.0 3.3 3.8 5.6 3.9 1.6 3.2 2.0 3.1 1.8 2.5 2.5 1.7 1.4 8.3 1.2 2.7 3.0 1.3 3.6 1.6 3.5 11.1 1.3 1.4 5.3 2.3 2.5 4.9 3.4 1.5 1.6 3.6 5.5 3.2 2.4 3.9 1.8 5.1 2.5 1.1 8.4 3.1 3.5 0.4 2.2 10.6 3.8 0.7 2.6 0.7 12.3 5.9 3.5 0.9 3.0 2.3 3.7 1.7 3.2 4.4 2.7 3.7 4.2 2.6 9.9 2.2 3.1 3.0 1.6 0.4 0.9 0.0 0.5 0.6 0.2 1.8 0.7 0.5 0.6 0.6 0.0 0.3 0.2 0.5 0.4 0.6 0.2 0.2 8.4 9.4 7.8 10.0 8.9 12.3 13.2 11.4 11.5 11.7 12.5 12.0 2.9 3.2 1.1 23.8 4.2 1.0 2.0 2.5 0.0 23.1 2.3 2.0 6.0 1.5 3.5 7.3 423.3 0.3 3.4 3.0 1.9 22.7 97.2 47.5 5.7 3.3 10.7 1.7 79.0 3.8 1.3 5.2 2.6 15.1 14.0 10.4 1.1 1.3 3.8 52.2 59.2 6.3 2.0 1.2 3.5 68.2 5.0 5.3 10.6 16.9 21.0 12.7 1.0 21.6 66.9 5.2 7.1 6.8 3.0 1.1 7.8 2.4 44.9 121.1 13.1 6.3 4.1 26.0 26.1 0.3 0.9 0.0 2.8 2.2 6.8 0.2 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 939.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 131.5;Early spermatids: 104.7;Hepatocytes: 444.9;Late spermatids: 124.3;Proximal tubular cells: 395.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 92.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 1600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favorable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.4 1.7 5.4 0.2 6.8 0.0 0.4 3.6 8.4 1.3 3.0 1.3 1.3 1.2 0.4 0.3 0.9 0.1 1.6 4.9 4.7 155.7 939.8 0.2 0.2 4.6 3.9 3.0 4.0 0.0 3.4 0.0 5.6 4.2 0.0 0.0 0.2 0.6 0.4 0.3 1.7 0.0 3.5 0.5 0.5 13.9 4.4 0.0 0.9 0.0 0.0 1.3 1.0 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.0 92.9 0.0 0.6 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.4 0.5 0.0 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 5.4 6.8 3.6 8.4 4.9 4.7 4.6 3.9 5.6 3.5 4.4 5.5 0.0 0.0 0.0 1.0 8.1 0.1 0.0 0.0 0.0 1.3 0.2 0.5 1.5 131.5 0.0 9.2 0.0 0.0 0.1 0.0 46.9 0.0 104.7 0.1 0.4 1.8 0.0 61.5 10.5 0.0 0.0 0.6 0.0 0.2 0.0 0.6 30.4 444.9 0.1 3.3 5.9 0.1 0.0 28.9 0.0 124.3 3.1 1.6 0.0 1.0 0.0 0.2 0.0 1.0 18.5 0.0 0.1 2.6 0.0 0.5 0.3 395.1 0.0 0.4 0.0 0.2 0.5 39.2 17.9 0.2 0.4 0.0 3.6 0.1 0.2 0.1 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.5;salivary gland: 66.2;stomach 1: 28.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 56.4;Club cells: 69.4;Distal enterocytes: 110.0;Gastric mucus-secreting cells: 83.6;Ionocytes: 57.0;Paneth cells: 75.5;Proximal enterocytes: 182.4;Undifferentiated cells: 62.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 63.6;OE19: 76.1" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.2 0.6 0.8 6.2 0.9 0.3 1.7 5.5 1.2 16.0 0.0 23.5 44.5 1.1 0.1 26.0 2.6 13.5 0.5 0.9 0.0 1.0 0.3 0.9 0.5 0.2 0.1 1.1 5.2 0.1 2.0 0.1 0.3 1.4 19.8 0.9 66.2 2.9 0.7 4.8 21.9 0.8 0.0 0.6 28.9 0.8 0.4 0.6 0.7 0.0 6.6 6.3 9.7 0.6 2.0 1.5 0.3 0.9 0.0 0.0 0.2 0.2 0.0 0.0 0.0 7.2 63.6 0.7 0.5 0.0 0.3 10.6 0.0 0.0 0.0 0.5 0.5 0.6 0.6 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.0 1.0 0.0 1.2 0.1 0.8 0.1 0.5 0.7 1.5 0.4 76.1 0.3 0.5 0.2 3.0 0.0 0.6 3.4 0.5 0.3 0.6 0.1 0.4 9.5 0.1 0.3 0.4 0.4 0.5 0.2 0.7 0.5 0.1 0.3 0.4 0.2 1.1 0.1 0.1 0.4 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.4 0.1 0.5 0.2 0.1 0.4 0.6 0.2 0.8 0.9 5.5 1.2 0.9 0.0 0.2 0.1 0.3 0.0 0.4 0.6 0.5 0.0 0.6 0.7 0.6 0.9 2.3 56.4 5.7 2.5 6.1 3.0 0.8 32.9 69.4 20.2 2.1 0.1 0.4 110.0 1.9 4.7 0.5 8.4 2.7 0.7 11.4 0.0 2.3 46.5 0.0 0.5 83.6 23.9 0.0 0.1 0.0 0.1 0.1 0.0 1.4 42.1 57.0 0.3 0.3 0.2 0.0 0.3 1.8 0.0 0.3 0.5 2.1 0.5 1.2 31.8 75.5 0.0 0.2 2.9 182.4 0.1 37.8 4.2 0.0 1.2 2.4 0.3 0.2 9.9 1.4 0.1 0.8 0.3 62.9 19.4 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 382.6;dendritic cells: 291.6;NK-cells: 228.6;Oligodendrocyte precursor cells: 342.8;Proximal tubular cells: 212.2;T-cells: 275.8" "Cancer enhanced" "Detected in all" "glioma: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 16 "NK-cells: 69.0;T-cells: 174.8" "Cell line enhanced" "Detected in many" "U-2197: 538.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" NA NA 820000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: AB_2685119" "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favorable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 76.6 10.8 117.1 52.4 106.4 32.3 46.8 83.8 104.3 45.5 33.3 32.9 16.4 45.6 33.8 16.0 51.4 32.1 40.5 102.1 121.5 23.9 20.4 63.5 108.9 136.3 104.9 28.8 8.5 18.7 22.9 29.7 107.0 17.6 15.6 26.9 12.9 12.5 12.3 41.5 47.1 38.0 109.9 71.9 29.3 16.5 105.7 86.1 45.7 18.3 67.6 48.4 33.4 109.8 10.4 1.5 178.6 30.2 133.4 81.4 3.2 29.1 90.8 24.2 42.9 1.3 1.6 21.0 18.3 56.1 21.0 1.3 25.8 39.9 46.8 0.7 66.5 57.0 13.6 2.7 78.7 19.5 19.0 78.8 59.1 90.5 76.8 62.9 99.5 99.6 4.9 140.3 86.8 1.5 92.7 17.9 26.0 3.3 18.0 29.1 24.0 1.4 0.0 9.1 124.6 50.7 5.7 2.4 124.7 39.6 1.3 57.0 63.9 72.3 13.5 538.7 18.5 20.0 19.7 32.5 136.0 44.3 128.9 1.1 6.4 0.2 137.0 5.6 174.8 4.8 83.9 152.7 7.4 6.4 27.9 72.3 3.0 69.0 4.2 4.3 79.2 51.5 117.1 106.4 83.8 104.3 102.1 121.5 136.3 104.9 107.0 109.9 105.7 109.8 87.8 0.0 8.3 382.6 26.0 17.1 2.5 0.6 1.8 57.2 2.9 6.9 11.3 14.3 2.1 7.3 0.0 2.7 291.6 1.2 17.6 9.3 3.7 5.6 51.7 70.3 13.2 20.9 118.7 1.0 2.4 61.9 17.9 4.9 52.0 20.9 76.4 60.3 3.0 47.1 127.6 3.8 2.0 35.8 96.1 3.2 26.4 42.7 37.4 88.1 64.5 89.1 228.6 342.8 162.3 9.7 0.1 7.2 96.2 3.9 17.7 212.2 4.4 8.3 13.1 48.8 32.9 3.9 8.6 0.7 13.4 52.0 275.8 71.1 2.9 1.1 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD2 ENSG00000180340 "Frizzled class receptor 2" Q14332 17 44557484-44561262 "Cancer-related genes, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 10.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Kupffer cells: 9.8;Leydig cells: 23.3;Peritubular cells: 18.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;myeloid DC: 1.8" "Group enriched" "Detected in many" 7 "dendritic cells: 1.8;monocytes: 1.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 53.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA057667 Uncertain Approved "Nucleoplasm,Nuclear bodies,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Nucleoplasm, Nuclear bodies" "Cell Junctions" "HPA057667: AB_2683497" "unprognostic (6.94e-2)" "unprognostic (1.12e-2)" "unprognostic (3.04e-2)" "unprognostic (8.83e-3)" "unprognostic (2.04e-1)" "unprognostic (5.29e-3)" "unprognostic (1.44e-2)" "unprognostic (2.29e-1)" "unprognostic (9.45e-2)" "unprognostic (5.61e-2)" "unprognostic (1.15e-2)" "unprognostic (1.86e-1)" "unprognostic (5.10e-3)" "unprognostic (1.19e-2)" "unprognostic (6.35e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-3)" 1.5 1.6 1.0 1.4 1.5 0.2 1.3 0.9 1.2 5.9 10.5 1.8 0.9 5.3 1.3 0.9 3.8 1.8 2.8 1.1 1.3 2.8 0.2 2.9 0.8 1.3 1.9 3.3 1.5 2.1 1.1 3.6 2.0 1.7 0.4 0.7 1.0 1.9 0.4 0.6 1.6 1.5 1.3 2.1 1.2 1.5 1.4 0.3 2.4 0.7 0.7 2.0 2.5 1.6 12.9 37.7 38.3 13.8 8.7 6.4 0.4 39.5 30.4 53.4 38.2 28.4 6.2 0.0 8.9 13.9 13.1 5.5 3.6 2.8 30.2 2.9 7.2 1.7 6.6 0.1 7.7 0.2 7.5 10.7 2.8 9.6 8.8 40.8 1.8 4.9 2.5 0.3 20.9 5.9 6.7 3.6 26.8 0.1 6.7 18.1 8.6 1.9 7.7 0.6 3.8 10.9 5.2 1.1 2.3 32.4 14.6 8.4 0.7 24.1 17.5 4.4 22.6 0.8 0.7 3.0 4.0 2.4 11.3 0.0 1.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 1.8 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.2 1.0 1.5 0.9 1.2 1.1 1.3 1.3 1.9 2.0 1.3 1.4 1.6 0.5 19.2 0.0 1.6 0.6 0.6 0.3 0.9 0.0 0.0 0.9 2.9 1.9 0.0 0.2 1.8 0.0 1.6 1.8 0.0 0.0 0.3 0.6 1.1 8.4 0.7 1.2 1.3 0.0 1.8 0.5 5.9 0.0 1.5 0.0 1.4 0.7 0.0 4.8 0.0 0.0 0.3 0.0 9.8 6.0 0.4 23.3 5.6 0.0 6.5 6.2 6.0 0.0 0.0 0.2 0.7 0.0 18.0 0.3 0.1 0.0 0.3 0.2 0.4 0.0 0.4 5.3 0.3 1.2 0.3 0.4 2.3 0.2 2.4 0.0 0.0 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GAB1 DFNB26 ENSG00000109458 "GRB2 associated binding protein 1" Q13480 4 143336762-143474568 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 114.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 162.7;Microglial cells: 192.0;Oligodendrocyte precursor cells: 288.0;Oligodendrocytes: 1013.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 5.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 74.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034333, HPA066404" Approved Approved "Nucleoli fibrillar center,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 14: REH - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoli fibrillar center, Plasma membrane" Cytosol "CAB034333: AB_2107855, HPA066404: " "unprognostic (1.14e-1)" "unprognostic (1.16e-1)" "unprognostic (1.32e-3)" "unprognostic (1.66e-1)" "unprognostic (4.71e-2)" "unprognostic (1.79e-2)" "unprognostic (4.17e-2)" "unprognostic (1.23e-1)" "unprognostic (1.35e-2)" "unprognostic (8.20e-2)" "unprognostic (2.10e-1)" "unprognostic (2.20e-1)" "prognostic favorable (3.91e-5)" "unprognostic (4.99e-2)" "unprognostic (2.70e-1)" "unprognostic (1.68e-1)" "unprognostic (1.91e-1)" 7.9 8.6 23.3 6.7 69.9 11.5 9.9 35.5 30.0 10.6 2.5 19.7 12.1 18.1 14.2 20.4 9.2 12.5 30.5 20.4 34.6 13.9 9.1 17.9 6.1 57.3 45.4 19.5 8.1 11.3 4.3 21.0 47.9 8.5 22.8 6.9 8.9 14.7 13.4 10.7 12.3 17.7 26.4 7.5 11.3 9.2 45.7 5.4 7.5 16.5 8.7 7.1 9.7 114.8 6.7 1.4 16.7 12.1 8.3 7.9 22.0 4.6 15.2 5.4 9.4 12.8 11.2 0.2 1.4 6.5 3.7 3.8 16.2 5.3 6.2 1.0 3.9 12.2 3.7 6.1 5.7 1.6 2.3 9.7 9.5 6.6 4.3 11.5 7.2 0.2 4.1 21.7 3.8 9.7 0.9 0.0 4.8 3.5 5.3 74.6 8.2 8.8 8.4 8.0 3.9 11.8 3.1 13.3 5.6 11.2 8.5 1.6 5.5 6.9 5.4 3.4 3.5 34.6 18.2 26.3 4.7 4.8 5.7 4.1 0.4 0.5 0.0 0.5 0.2 0.9 0.0 0.0 0.5 1.8 0.0 0.0 2.6 5.0 1.7 2.2 0.0 0.3 23.3 69.9 35.5 30.0 20.4 34.6 57.3 45.4 47.9 26.4 45.7 114.8 13.4 28.9 19.0 89.5 13.1 20.3 8.8 3.3 12.0 2.1 11.6 8.9 34.0 8.6 5.3 12.9 0.0 23.5 10.9 26.2 0.0 6.6 0.9 8.8 9.3 16.3 22.2 40.8 162.7 2.6 10.6 14.4 11.2 21.6 2.5 9.6 13.9 7.0 6.1 3.3 62.2 27.8 4.1 11.6 10.2 3.8 20.8 8.8 16.0 192.0 5.6 15.4 1.0 288.0 1013.6 4.9 10.7 18.8 94.4 7.2 9.3 5.4 3.4 0.8 13.1 7.0 14.3 2.0 5.3 19.9 24.9 10.4 2.7 4.4 13.6 13.5 GAB2 KIAA0571 ENSG00000033327 "GRB2 associated binding protein 2" Q9UQC2 11 78215293-78418348 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 147.9;Microglial cells: 204.2;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 480.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.0;neutrophil: 20.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 20.1" "Cell line enhanced" "Detected in many" "SH-SY5Y: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000271, HPA001368, CAB022159" Enhanced Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB022159: , HPA000271: AB_1078925, HPA001368: AB_2666287" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (3.56e-3)" "unprognostic (1.99e-3)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (4.47e-2)" "unprognostic (1.08e-1)" "unprognostic (6.54e-2)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (1.74e-1)" "prognostic favorable (9.32e-5)" "unprognostic (6.95e-2)" "unprognostic (4.35e-1)" "unprognostic (3.99e-2)" "unprognostic (1.67e-2)" 18.5 8.2 69.5 12.9 80.7 39.9 11.6 56.2 65.3 14.8 31.2 9.4 14.4 19.8 3.1 8.9 13.6 9.3 14.5 54.5 68.4 6.7 4.4 20.0 7.0 79.4 70.9 20.0 6.8 6.8 8.8 15.5 74.0 7.0 11.0 3.5 7.1 7.1 6.4 13.3 10.7 17.3 68.0 13.1 8.2 5.7 72.0 21.3 6.6 6.8 5.8 10.6 10.9 97.9 3.7 3.1 8.8 1.0 12.7 5.4 39.1 5.7 6.8 4.0 3.3 23.8 1.9 1.1 24.8 7.9 1.0 5.9 21.2 0.5 5.2 36.3 2.2 14.6 5.9 4.2 6.3 5.6 2.8 6.1 1.9 15.6 2.4 11.8 23.4 4.2 38.8 1.2 6.7 1.5 2.8 13.8 2.8 8.4 4.4 27.4 8.5 0.5 7.3 13.4 7.6 62.1 1.4 2.9 14.4 12.7 13.2 15.5 19.4 1.8 4.5 15.2 1.4 9.8 1.5 0.6 1.5 8.6 16.8 13.0 3.1 0.9 0.0 1.7 0.0 0.7 0.0 0.0 1.0 0.4 0.0 0.0 20.1 0.0 4.9 2.2 0.2 1.0 69.5 80.7 56.2 65.3 54.5 68.4 79.4 70.9 74.0 68.0 72.0 97.9 6.6 3.2 20.7 57.5 8.7 2.0 0.7 0.5 0.6 4.3 3.6 2.7 10.9 1.5 1.1 0.0 0.0 5.0 4.0 9.2 0.0 2.5 7.0 5.5 9.1 7.6 10.7 4.2 80.7 6.4 16.6 6.9 6.6 10.6 5.7 50.4 5.3 0.8 12.1 16.8 147.9 4.0 4.1 29.5 17.5 5.1 8.1 22.8 7.2 204.2 17.5 0.5 1.0 142.7 480.3 8.2 3.3 10.9 4.2 4.3 10.5 0.8 2.6 2.1 13.1 8.3 5.4 3.7 1.7 1.8 2.8 22.2 3.5 3.5 8.9 2.2 GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 55.1;retina: 17.8" "Group enriched" "Detected in some" 11 "Bipolar cells: 198.0;Excitatory neurons: 220.5;Inhibitory neurons: 215.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: AB_2682904" "unprognostic (2.58e-2)" "unprognostic (4.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.31e-1)" "unprognostic (2.43e-1)" 0.0 1.2 6.7 0.0 11.1 0.0 0.0 24.8 55.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.7 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 14.3 0.6 0.0 0.0 0.2 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 11.1 24.8 55.1 7.7 21.7 0.0 0.0 0.0 0.0 14.3 24.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 215.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 17.8 0.0 3.5 0.0 8.0 16.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 5 "Astrocytes: 425.4;Excitatory neurons: 156.2;Inhibitory neurons: 111.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "U-2 OS: 4.2;U-87 MG: 2.1;WM-115: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 1.2 0.3 20.2 0.4 29.9 0.2 1.3 2.6 31.5 0.5 0.0 3.0 0.9 0.4 8.8 0.7 0.0 0.5 0.2 29.4 16.0 6.3 0.4 0.1 0.3 0.3 1.9 0.7 0.1 0.0 0.5 0.4 0.0 0.1 2.1 2.4 0.2 0.7 0.1 0.2 6.0 0.2 1.3 1.2 0.5 0.5 13.8 0.4 0.1 0.1 0.4 0.2 0.7 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 4.2 0.2 0.0 0.2 0.6 0.0 2.1 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 29.9 2.6 31.5 29.4 16.0 0.3 1.9 0.0 1.3 13.8 8.8 4.9 0.0 0.0 425.4 0.0 0.1 0.0 0.0 1.2 15.3 0.2 0.0 0.6 0.0 0.0 40.5 4.2 0.0 0.0 23.1 3.9 0.0 9.1 1.2 31.7 1.0 31.8 0.0 156.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 111.6 3.4 0.0 0.0 0.0 17.1 0.6 0.1 1.8 16.9 0.0 0.2 0.0 13.0 5.5 0.0 4.7 0.0 0.0 0.0 38.1 0.1 0.0 1.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.0 2.7 0.0 GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.5;choroid plexus: 16.3;retina: 9.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 70.3;Hofbauer cells: 16.2;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 9.9;HMC-1: 8.4;Karpas-707: 14.4;PC-3: 8.4;U-266/70: 7.7;U-266/84: 13.6;U-87 MG: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" 0.0 0.0 10.0 0.0 13.7 0.0 0.0 0.0 13.2 0.9 16.3 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 9.6 15.5 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.6 2.9 3.0 0.1 0.0 9.0 0.1 0.6 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.7 11.2 0.0 0.0 0.0 0.1 0.4 0.2 2.7 0.0 0.8 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 14.4 0.0 0.0 0.0 0.0 2.6 6.4 8.4 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 5.3 0.4 0.3 0.1 1.3 0.1 5.3 7.0 0.3 1.6 7.7 13.6 0.0 8.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.7 0.0 13.2 9.6 15.5 0.9 4.0 3.0 0.6 11.2 2.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.6 1.2 0.0 0.0 0.3 0.0 0.0 0.0 2.1 3.2 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.1 0.0 0.0 70.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.2 1.7 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 3.0 0.0 58.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.9 0.0 1.9 0.0 0.0 0.0 0.5 GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 111.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 27.6;Inhibitory neurons: 14.1" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Group enriched" "Detected in many" 4 "amygdala: 52.0;basal ganglia: 73.5;cerebral cortex: 98.6;hippocampal formation: 111.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A549: 35.3;HAP1: 12.0;NTERA-2: 16.2;U-2 OS: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079022: , HPA029363: , HPA077031: AB_2686825" "unprognostic (6.33e-2)" "unprognostic (8.94e-3)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (9.50e-3)" "unprognostic (2.57e-1)" "unprognostic (7.63e-2)" "unprognostic (8.50e-2)" "unprognostic (1.44e-2)" 0.0 0.0 52.0 0.1 73.5 0.0 0.0 0.0 98.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.5 111.0 7.2 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.7 0.5 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.7 12.0 9.0 0.1 0.1 0.3 0.0 0.0 19.6 0.0 35.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 12.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.1 0.2 1.8 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 73.5 0.0 98.6 111.0 7.2 0.0 3.0 0.0 0.0 12.0 19.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.8 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GABRG1 ENSG00000163285 "Gamma-aminobutyric acid type A receptor subunit gamma1" Q8N1C3 4 46035769-46124054 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 44.7" "Cell type enriched" "Detected in some" 8 "Astrocytes: 135.5" "Cancer enriched" "Detected in single" 8 "glioma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035622, HPA058102" Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA035622: AB_10603669, HPA058102: " "unprognostic (2.50e-1)" "unprognostic (2.20e-1)" "unprognostic (6.06e-2)" "unprognostic (1.46e-2)" "unprognostic (7.39e-4)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" 0.1 0.1 21.6 0.0 20.6 0.0 0.0 19.0 27.3 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 19.4 31.7 0.0 0.0 0.0 0.0 24.8 38.0 1.2 0.0 0.0 0.6 0.0 23.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.2 44.7 0.0 0.1 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 20.6 19.0 27.3 19.4 31.7 24.8 38.0 23.9 21.1 44.7 23.1 0.3 0.0 0.0 135.5 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.2 0.0 15.4 0.0 2.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.6 0.0 1.8 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GAD1 GAD ENSG00000128683 "Glutamate decarboxylase 1" Q99259 2 170813213-170861151 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Neurotransmitter biosynthesis" "Decarboxylase, Lyase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 98.5;parathyroid gland: 46.3;retina: 29.7" "Group enriched" "Detected in many" 8 "Inhibitory neurons: 392.8;Oligodendrocyte precursor cells: 146.8" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 20.1;HEL: 64.5" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "olfactory bulb: 547.6" "CAB004415, HPA048871, HPA058412, CAB078176" Enhanced Supported Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "CAB004415: AB_627650, CAB078176: AB_2665792, HPA048871: , HPA058412: AB_2683710" "unprognostic (1.28e-1)" "prognostic favorable (7.31e-4)" "unprognostic (1.87e-2)" "prognostic favorable (8.61e-4)" "unprognostic (1.12e-1)" "unprognostic (3.05e-1)" "unprognostic (4.97e-7)" "unprognostic (1.51e-1)" "unprognostic (7.72e-2)" "unprognostic (4.27e-4)" "unprognostic (6.75e-2)" "unprognostic (9.18e-3)" "unprognostic (6.90e-5)" "unprognostic (2.93e-2)" "unprognostic (6.57e-2)" "unprognostic (1.56e-2)" "unprognostic (3.08e-3)" 0.2 3.0 22.1 0.0 29.9 3.3 0.1 15.5 33.0 1.0 0.0 0.0 0.0 1.6 4.3 0.4 0.2 0.1 0.0 17.1 98.5 4.8 0.1 0.2 0.1 12.4 41.6 0.2 0.2 46.3 5.0 0.4 17.6 0.8 0.1 29.7 0.1 0.3 0.0 0.2 0.1 0.0 12.7 0.1 0.0 3.2 31.1 0.8 0.1 0.0 0.2 0.6 0.4 14.2 18.2 0.7 0.0 7.3 0.0 0.0 0.1 0.4 0.0 2.6 1.7 4.6 6.7 0.0 0.9 0.5 2.9 20.1 2.3 0.6 1.6 2.8 13.4 64.5 6.0 0.2 0.0 0.3 1.1 0.0 5.5 0.0 2.3 0.6 0.1 0.5 17.0 0.3 0.8 1.5 0.0 0.0 8.1 9.7 6.7 1.0 4.6 0.4 8.5 9.4 6.7 2.1 12.6 0.0 3.5 0.6 0.2 0.0 0.0 12.0 1.7 2.4 7.0 0.0 0.0 0.1 11.5 3.2 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 29.9 15.5 33.0 17.1 98.5 12.4 41.6 17.6 12.7 31.1 14.2 0.0 0.0 0.0 14.7 0.0 0.3 2.1 7.7 2.2 32.5 0.1 0.1 1.3 0.0 3.6 0.0 10.4 0.0 0.0 0.2 7.9 4.5 5.6 4.4 0.4 0.4 3.0 5.5 2.6 5.6 0.1 0.2 0.0 2.9 0.0 5.5 0.0 0.0 4.0 5.0 392.8 0.3 2.0 0.8 0.4 6.2 0.6 0.5 0.0 7.5 0.0 4.9 0.0 146.8 7.6 2.9 0.0 0.0 0.1 0.9 0.0 0.0 4.7 6.0 0.0 0.0 1.2 4.4 7.7 0.6 0.1 0.5 0.0 0.1 0.1 0.4 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 25.8;tongue: 11.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Club cells: 1.3;Collecting duct cells: 1.8;Fibroblasts: 5.9;Late spermatids: 1.8;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;TIME: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.3 0.4 2.2 0.4 2.1 1.2 0.4 2.6 2.5 0.1 0.1 0.2 0.2 0.3 0.6 0.6 0.2 0.3 0.6 1.8 0.8 0.7 0.3 0.3 0.4 0.9 0.5 0.6 0.4 0.2 0.2 0.3 0.9 0.6 0.2 1.7 0.4 0.1 25.8 0.9 0.2 0.2 0.1 0.6 0.3 0.5 1.0 0.1 0.9 11.3 0.3 0.2 0.0 2.3 0.4 0.0 0.2 0.4 0.3 0.1 0.5 0.2 0.1 0.0 0.0 0.5 0.5 0.4 0.2 0.0 0.2 0.3 4.7 0.1 0.1 0.6 0.1 0.5 0.8 0.2 0.0 0.3 1.3 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.5 1.7 0.2 0.3 0.2 0.5 0.5 0.1 0.1 0.7 0.9 0.4 0.2 0.6 0.5 0.3 0.2 0.3 1.3 0.3 0.4 0.3 2.4 0.6 0.5 0.8 0.2 0.6 0.3 0.3 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.2 2.1 2.6 2.5 1.8 0.8 0.9 0.5 0.9 0.1 1.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 1.8 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 GAGE1 CT4.1 ENSG00000205777 "G antigen 1" P0DTW1 X 49599025-49608536 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 49 "testis: 9.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 113.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "AN3-CA: 739.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 739.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 139.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 60.5 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 1.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 24.4 113.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE10 ENSG00000215274 "G antigen 10" A6NGK3 X 49303669-49319844 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.0;testis: 1.6" "Cell type enhanced" "Detected in some" "Granulosa cells: 2.1;Leydig cells: 1.2;Microglial cells: 1.0;Peritubular cells: 1.2;Spermatocytes: 3.2;Spermatogonia: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.5;WM-115: 1.0" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" "unprognostic (2.81e-2)" "unprognostic (2.26e-1)" "unprognostic (3.97e-1)" 0.0 0.0 1.0 0.0 1.4 0.0 0.2 0.9 2.0 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.4 0.0 0.1 1.0 0.8 0.0 0.0 0.0 0.2 0.9 1.1 0.9 0.0 0.0 0.8 0.0 1.0 0.1 0.1 0.6 0.0 0.3 0.1 0.0 0.0 0.3 0.9 0.1 0.0 1.6 0.8 0.0 0.2 0.0 0.1 0.1 0.0 1.0 0.0 0.0 0.2 2.5 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.9 2.0 1.0 0.8 0.9 1.1 1.0 0.9 0.8 1.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 3.2 5.2 0.0 0.1 0.0 0.0 0.6 0.0 0.1 GAGE12C ENSG00000237671 "G antigen 12C" A1L429 X 49532211-49539538 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 271 "testis: 27.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/84: 37.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 9.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12D ENSG00000227488 "G antigen 12D" A1L429 X 49541767-49549094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 271 "testis: 27.0" "Cell type enriched" "Detected in single" 10 "Spermatogonia: 1.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "U-266/84: 37.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.4 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.7 0.0 0.0 0.1 9.1 0.0 0.0 0.0 37.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12E ENSG00000216649 "G antigen 12E" A1L429 X 49551333-49558649 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 1.8" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 11.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.4;U-266/84: 2.1" HPA043232 Supported Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.3 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12F ENSG00000236362 "G antigen 12F" "P0CL80, O76087, P0CL82" X 49551278-49568218 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 17 "testis: 178.7" "Cell type enhanced" "Detected in single" "Spermatogonia: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "AN3-CA: 1630.3;K-562: 1415.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 10.7 178.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 9.9 0.0 0.0 1630.3 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 3.1 0.0 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1415.3 30.0 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 360.9 0.0 5.1 56.9 7.5 0.3 1.0 0.6 72.0 0.0 0.2 0.0 171.2 1.3 11.5 4.6 4.8 12.1 3.4 8.4 12.6 8.7 0.0 7.8 9.7 8.6 1.4 14.7 10.5 12.4 20.2 11.5 0.4 0.6 0.2 0.3 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12G ENSG00000215269 "G antigen 12G" "P0CL81, O76087, P0CL82" X 49570434-49577754 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 31 "retina: 1.6;stomach 1: 6.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 4.7" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 8 "AN3-CA: 439.0" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 4: Stomach - Digestion" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 439.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 54.7 0.0 0.0 8.4 0.5 0.1 0.2 0.0 0.0 0.0 0.2 0.0 20.8 0.2 1.5 0.9 0.5 1.6 0.8 0.8 2.0 0.2 0.0 1.5 0.3 1.7 0.0 0.3 1.4 0.9 4.7 2.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12H ENSG00000224902 "G antigen 12H" A6NDE8 X 49579983-49587301 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 230 "testis: 22.9" "Group enriched" "Detected in some" 15 "Spermatocytes: 1.4;Spermatogonia: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "A-431: 53.9;U-266/84: 164.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 36: Testis - Spermatogenesis" "Cluster 16: U-266 - Nucleosome" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.9 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.3 1.4 0.0 0.0 0.0 164.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE12J GAGE11 ENSG00000224659 "G antigen 12J" A6NER3 X 49322057-49329384 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 45 "testis: 35.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 22 "AN3-CA: 1145.9;K-562: 290.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 35.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 1145.9 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 2.1 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 290.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 32.4 0.0 0.0 0.0 0.2 0.5 0.0 2.5 32.2 0.1 0.0 0.0 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE13 GAGE12A ENSG00000274274 "G antigen 13" Q4V321 X 49331616-49338952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 36.1" "Group enriched" "Detected in some" 22 "Spermatocytes: 4.2;Spermatogonia: 13.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "AN3-CA: 303.6;T-47d: 165.3;WM-115: 83.9" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 36.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 303.6 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 3.6 0.0 2.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 165.3 0.0 0.7 3.4 1.1 0.2 0.0 0.0 0.6 0.0 0.0 0.0 83.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE2A "CT4.2, GAGE2" ENSG00000189064 "G antigen 2A" Q6NT46 X 49589529-49596827 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 108 "testis: 92.5" "Group enriched" "Detected in some" 17 "Spermatocytes: 108.0;Spermatogonia: 358.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "Karpas-707: 86.8;T-47d: 289.7;WM-115: 325.3" HPA043232 Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" "unprognostic (1.29e-1)" 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 5.8 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 20.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 86.8 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 3.8 0.0 0.0 289.7 0.0 0.0 47.3 10.6 0.1 0.0 1.2 13.8 0.0 2.9 0.0 325.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 13.1 0.0 0.0 108.0 358.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GAGE2E GAGE8 ENSG00000275113 "G antigen 2E" Q4V326 X 49341192-49345922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 13 "stomach 1: 12.8;testis: 26.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "T-reg: 2.9" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "AN3-CA: 2587.1;K-562: 674.0" HPA043232 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 23: AN3-CA - Transcription regulation" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA043232: AB_2678376" 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.2 12.8 26.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2587.1 0.0 0.4 2.2 0.0 0.0 0.0 0.0 0.0 4.3 1.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.7 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 674.0 12.0 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.3 0.2 0.0 5.0 0.3 0.3 364.7 0.1 3.3 61.8 2.4 0.2 0.2 0.8 20.9 0.0 0.7 0.2 138.5 0.4 0.6 0.1 0.5 0.0 0.0 0.6 0.1 1.0 0.0 1.2 2.1 0.0 0.4 0.4 0.0 1.5 2.9 0.1 0.1 0.3 0.0 0.3 0.2 0.0 0.1 0.5 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GALNT10 GalNAc-T10 ENSG00000164574 "Polypeptide N-acetylgalactosaminyltransferase 10" Q86SR1 5 154190730-154420984 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 65.8" "Cell type enhanced" "Detected in many" "Microglial cells: 74.0;Oligodendrocyte precursor cells: 156.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 284.9;TIME: 161.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007525 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA007525: AB_1849443" "unprognostic (6.99e-2)" "unprognostic (4.33e-2)" "unprognostic (9.85e-2)" "prognostic favorable (3.33e-6)" "unprognostic (1.63e-1)" "unprognostic (6.98e-2)" "unprognostic (6.95e-3)" "unprognostic (2.38e-1)" "unprognostic (3.34e-1)" "prognostic unfavorable (5.69e-4)" "unprognostic (2.88e-3)" "unprognostic (2.63e-1)" "unprognostic (1.54e-1)" "unprognostic (7.76e-3)" "unprognostic (1.22e-1)" "unprognostic (1.61e-2)" "unprognostic (3.08e-1)" 12.1 15.6 10.7 14.4 14.5 19.3 13.5 12.1 10.0 24.1 33.0 16.1 14.4 6.3 6.0 4.9 14.6 16.7 9.0 9.5 12.5 9.7 4.4 15.5 9.9 16.1 13.9 65.8 9.8 13.6 11.5 4.7 12.3 9.1 14.7 7.8 13.5 3.7 5.4 6.0 12.6 11.6 9.9 15.8 22.0 4.5 13.9 7.8 16.6 8.2 9.4 11.1 5.2 12.6 25.6 85.3 20.3 17.8 42.2 37.3 15.6 71.7 39.9 27.9 26.7 12.1 56.7 16.6 49.3 121.4 49.9 4.4 9.4 56.0 25.4 43.2 6.7 45.4 16.0 16.5 32.4 9.9 42.3 46.7 12.9 22.7 33.2 284.9 54.4 12.5 10.5 50.9 48.4 26.4 1.1 6.8 8.0 71.1 17.3 5.1 10.7 16.6 38.6 17.1 2.7 6.6 31.8 117.0 9.4 29.6 45.6 7.4 161.2 67.5 15.9 16.8 77.7 14.5 15.0 8.7 44.2 19.3 21.1 2.0 1.2 2.4 3.1 1.6 2.8 1.9 1.8 2.0 1.4 2.1 0.8 2.1 2.5 1.9 1.8 1.1 1.6 1.0 10.7 14.5 12.1 10.0 9.5 12.5 16.1 13.9 12.3 9.9 13.9 12.6 17.4 9.6 46.4 32.7 17.4 4.8 3.9 5.6 1.8 4.6 12.4 8.6 5.0 5.7 8.7 14.7 4.2 0.7 27.7 23.0 9.8 9.1 10.3 12.4 7.4 14.1 3.0 21.4 14.3 30.1 1.5 13.7 30.5 22.3 10.2 10.5 23.9 5.3 8.5 0.0 15.9 20.4 6.1 19.5 7.8 22.5 38.2 12.4 0.0 74.0 11.9 17.4 44.3 156.9 66.9 36.8 13.6 50.0 15.4 8.2 15.3 2.7 0.7 10.5 6.6 5.6 7.8 2.0 4.0 1.2 3.7 0.8 21.7 27.3 12.2 4.2 GALNT12 GalNAc-T12 ENSG00000119514 "Polypeptide N-acetylgalactosaminyltransferase 12" Q8IXK2 9 98807670-98850081 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 74.7;intestine: 55.8;stomach 1: 54.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 101.2;Intestinal goblet cells: 142.4;Undifferentiated cells: 42.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 128.4;U-2197: 160.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA048292, HPA071076" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA048292: AB_2680343, HPA071076: " "unprognostic (7.85e-3)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (1.47e-2)" "unprognostic (2.97e-3)" "unprognostic (4.10e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.03e-2)" "unprognostic (1.97e-1)" "unprognostic (2.61e-2)" "unprognostic (7.71e-2)" "prognostic favorable (3.24e-4)" "unprognostic (9.05e-2)" "unprognostic (1.92e-1)" "unprognostic (1.60e-3)" "unprognostic (6.87e-2)" 5.0 2.0 1.2 7.7 1.3 2.2 3.4 6.5 1.8 8.7 4.3 55.3 34.2 3.7 74.7 19.6 7.5 10.5 1.2 1.1 1.4 4.8 0.4 11.7 3.2 2.6 1.4 0.4 13.6 6.3 3.4 2.6 2.7 4.6 55.8 0.6 25.5 4.3 1.3 3.4 27.1 14.0 1.1 2.2 54.8 4.6 1.5 3.3 14.7 0.6 6.1 11.9 4.6 1.6 5.4 4.1 3.4 13.5 10.0 7.8 0.0 1.4 2.1 2.0 4.6 0.8 21.6 0.0 5.0 0.9 12.2 38.0 2.9 1.3 1.6 26.2 1.7 2.4 0.2 0.0 0.5 1.6 0.5 3.8 0.9 6.4 0.0 2.7 2.3 19.3 30.2 0.0 0.6 13.9 2.6 4.7 16.7 128.4 5.6 6.5 0.3 0.1 2.3 7.7 12.4 1.1 0.5 30.6 3.0 7.7 4.5 4.5 4.3 0.0 0.3 160.9 0.0 2.1 4.8 2.3 37.1 0.0 0.9 0.0 0.0 0.5 0.3 0.0 0.6 0.0 0.4 0.2 0.0 0.1 0.6 0.3 0.0 0.6 0.0 0.1 0.0 0.1 1.2 1.3 6.5 1.8 1.1 1.4 2.6 1.4 2.7 1.1 1.5 1.6 1.3 3.2 25.7 2.0 2.3 2.4 1.3 8.3 1.2 2.4 0.4 0.1 1.0 18.6 16.9 11.0 16.7 1.0 2.6 101.2 0.0 11.2 1.8 4.8 1.6 1.6 19.9 1.3 7.4 25.4 1.7 12.5 32.1 8.7 2.5 2.4 0.0 0.0 2.3 0.0 5.7 142.4 2.0 0.3 3.9 1.4 2.1 3.9 0.0 3.7 0.2 0.8 3.1 3.5 7.0 32.0 36.5 7.5 1.7 7.4 21.9 2.7 16.9 0.2 0.0 0.7 1.5 5.9 10.5 9.9 1.3 1.1 4.5 5.1 42.5 11.1 GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;brain: 1.9;pituitary gland: 1.4" "Cell type enhanced" "Detected in some" "Early spermatids: 68.1;Enteroendocrine cells: 17.6;Oligodendrocyte precursor cells: 42.7;Respiratory ciliated cells: 11.7" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in many" HPA074584 Supported "Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" 0.1 1.4 0.8 0.1 0.5 0.2 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 1.5 0.0 0.2 0.0 0.0 1.1 1.6 0.0 0.0 0.2 1.4 0.0 0.8 0.2 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.1 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.8 0.7 1.5 1.1 1.6 0.8 1.3 1.9 0.8 4.2 0.0 3.6 0.0 0.0 0.0 1.1 0.0 0.0 4.2 0.0 0.0 0.6 0.0 0.6 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.1 0.3 0.1 0.3 17.6 0.0 1.4 0.0 0.0 1.0 0.0 0.3 1.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.3 0.0 0.0 0.1 0.2 1.0 42.7 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.1 11.7 0.4 0.0 3.1 0.2 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 1.2 GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "brain: 277.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 270.2" "Cancer enriched" "Detected in many" 43 "glioma: 245.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.9;NTERA-2: 81.1;SCLC-21H: 52.2;SH-SY5Y: 39.6;U-87 MG: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004417: AB_627660, CAB078783: AB_2620096, HPA013392: AB_1849468, HPA015600: AB_1849466" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-2)" "unprognostic (5.72e-5)" "unprognostic (7.44e-3)" "unprognostic (2.19e-2)" "unprognostic (3.97e-3)" "unprognostic (3.15e-3)" "unprognostic (6.08e-4)" "unprognostic (3.33e-1)" "unprognostic (2.17e-2)" "unprognostic (1.62e-1)" "unprognostic (5.35e-8)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.29e-3)" 0.6 6.3 131.6 7.5 149.2 0.0 0.9 36.3 277.0 0.6 0.0 10.5 2.5 0.2 0.1 1.1 0.2 4.7 4.3 149.9 187.2 0.2 0.2 0.3 0.2 55.6 156.5 0.2 0.8 0.0 10.0 1.7 113.3 0.9 4.8 8.0 2.1 0.3 0.3 0.5 5.5 4.3 28.5 0.0 2.9 0.4 150.7 0.1 0.2 0.6 0.4 1.3 1.9 121.0 0.0 0.0 37.9 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.6 0.0 0.5 0.0 0.0 0.0 9.1 0.2 0.0 0.0 0.0 81.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.2 39.6 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.1 0.0 0.0 18.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 131.6 149.2 36.3 277.0 149.9 187.2 55.6 156.5 113.3 28.5 150.7 121.0 0.1 0.0 0.0 20.9 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.8 5.1 0.0 0.0 270.2 0.0 0.1 4.5 0.0 0.0 0.0 1.5 0.0 0.0 0.8 0.0 62.5 0.0 0.0 0.0 1.2 1.8 0.0 0.0 1.8 29.0 0.0 1.4 0.0 40.2 20.2 0.8 0.0 0.0 0.4 0.0 0.0 0.2 0.0 3.5 0.0 2.0 1.1 0.9 1.7 0.0 0.1 0.0 0.1 0.3 0.0 0.0 GAPDH GAPD ENSG00000111640 "Glyceraldehyde-3-phosphate dehydrogenase" P04406 12 6534512-6538374 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Glycolysis, Immunity, Innate immunity, Translation regulation" "Oxidoreductase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 27580.7;tongue: 18892.5" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 10357.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "CAB005197, CAB016392, HPA040067, HPA061280, CAB079968" Supported Enhanced "Nuclear membrane,Vesicles,Plasma membrane,Cytosol" No No 1400000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "Nuclear membrane, Vesicles" "CAB005197: AB_641107, CAB016392: AB_627678, CAB079968: , HPA040067: AB_10965903, HPA061280: AB_2684463" "unprognostic (3.03e-1)" "unprognostic (2.62e-3)" "unprognostic (3.58e-2)" "unprognostic (4.20e-1)" "unprognostic (9.73e-3)" "unprognostic (1.77e-3)" "prognostic unfavorable (1.79e-6)" "unprognostic (2.89e-3)" "unprognostic (2.86e-1)" "unprognostic (2.06e-2)" "unprognostic (9.50e-3)" "unprognostic (4.52e-1)" "prognostic unfavorable (6.25e-10)" "unprognostic (2.33e-1)" "unprognostic (4.28e-1)" "unprognostic (1.40e-1)" "unprognostic (1.26e-2)" 1219.9 1815.8 2605.9 1191.3 2589.5 4608.5 1042.3 2869.0 3067.8 1163.8 2419.2 1720.0 1480.8 1080.9 769.9 2973.8 1042.8 1161.3 5572.8 2630.1 2880.0 2323.2 2557.9 1137.9 1388.3 2845.2 2861.3 1087.0 652.0 1616.0 1338.7 1190.6 2828.4 1241.0 1586.6 2386.8 1835.8 1238.7 27580.7 1775.5 1457.5 1424.4 2670.8 1208.5 1215.5 693.0 2985.1 1570.9 1022.1 18892.5 1861.0 1889.0 1672.9 2741.6 6063.0 10247.9 3109.5 4709.2 3026.2 5018.7 6516.0 4716.2 7218.1 7172.8 7491.2 7211.3 4091.6 7540.8 878.2 5947.4 4904.2 3359.8 3372.7 10829.1 5432.4 6263.1 3229.5 4224.9 5857.5 6279.2 3890.9 6710.2 3046.1 4089.0 3521.7 6553.0 7609.7 15565.8 7762.7 5052.4 2215.9 1484.1 8670.0 11849.8 7303.1 3247.3 10995.7 7254.7 3950.7 5849.8 5505.7 3512.8 7909.6 7115.9 2088.3 3331.0 4243.1 10206.4 5984.0 8874.7 1657.2 4311.2 4794.3 5049.0 5907.2 2717.1 7931.5 3178.4 2544.6 9374.4 10632.2 4050.5 8040.5 2575.4 4295.8 737.9 1325.8 2011.2 1171.4 1046.9 1364.8 1333.1 3253.6 652.5 757.6 886.9 1981.4 1227.8 1900.6 474.6 2126.1 6812.0 2605.9 2589.5 2869.0 3067.8 2630.1 2880.0 2845.2 2861.3 2828.4 2670.8 2985.1 2741.6 1036.7 237.2 259.5 228.2 1086.9 1818.8 2223.4 7367.5 4070.9 1157.6 1794.6 3689.2 40.4 1263.9 2213.7 1022.5 417.0 4237.7 1032.7 2579.6 3463.0 5198.9 759.8 770.1 702.4 1597.4 1324.3 1180.6 112.1 3794.5 10357.8 1127.1 1068.8 1021.8 562.3 2063.7 1242.9 1742.3 3895.3 2348.7 145.8 2351.2 2543.1 2586.7 2494.4 2257.7 889.4 2134.0 4220.8 86.2 3422.3 6177.9 1045.4 98.5 196.2 5681.8 3001.4 1026.9 2668.2 1714.0 5714.0 7286.7 864.3 1435.2 1150.4 1744.7 2827.8 429.9 476.2 3605.2 1600.7 4694.0 1514.9 1839.0 3140.9 2882.4 GAPT "C5orf29, FLJ33641" ENSG00000175857 "GRB2 binding adaptor protein, transmembrane" Q8N292 5 58491435-58497090 "Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 16.9;lymphoid tissue: 42.7" "Cell type enhanced" "Detected in some" "B-cells: 84.8;dendritic cells: 160.1;granulocytes: 55.0;Macrophages: 43.0;monocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 1000.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 1000.3" "Cell line enhanced" "Detected in some" "HEL: 71.5;HL-60: 41.8;NB-4: 43.3;THP-1: 33.7;U-937: 118.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA011048, HPA011070" Uncertain Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA011048: , HPA011070: AB_1848887" "unprognostic (9.79e-2)" "unprognostic (5.67e-3)" "unprognostic (2.39e-2)" "unprognostic (3.26e-2)" "unprognostic (3.36e-2)" "unprognostic (8.09e-4)" "unprognostic (4.32e-1)" "unprognostic (1.23e-3)" "unprognostic (4.14e-2)" "unprognostic (9.47e-3)" "unprognostic (7.28e-2)" "unprognostic (2.93e-1)" "unprognostic (3.52e-3)" "unprognostic (3.74e-2)" "unprognostic (2.42e-2)" "unprognostic (2.33e-2)" "unprognostic (1.40e-2)" 1.7 0.8 0.7 28.5 0.7 16.9 2.3 0.7 1.1 2.7 1.3 2.7 3.7 1.3 1.1 2.1 1.6 5.7 0.7 0.7 1.0 0.8 2.0 4.2 25.3 1.3 1.1 0.4 1.1 1.1 0.6 1.0 1.3 1.8 3.8 0.5 1.9 1.2 0.2 0.8 6.6 4.7 1.0 18.2 3.7 0.7 1.1 6.9 0.6 0.7 42.7 6.0 0.5 1.8 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 71.5 0.2 0.0 0.0 41.8 12.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.0 0.0 43.3 0.0 0.0 0.0 17.7 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 33.7 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 118.4 0.0 125.5 66.7 1000.3 0.4 46.5 0.5 97.0 0.4 0.4 76.8 97.4 0.3 0.3 82.0 1.4 59.3 205.4 0.3 32.0 0.7 0.7 0.7 1.1 0.7 1.0 1.3 1.1 1.3 1.0 1.1 1.8 0.4 3.2 1.9 0.0 84.8 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.2 0.0 0.6 0.0 0.0 0.0 160.1 0.0 0.0 0.0 1.6 0.0 0.1 0.9 0.0 8.8 0.0 0.0 0.1 0.4 0.5 0.0 55.0 0.0 0.4 0.0 14.3 0.0 0.0 0.0 0.0 19.4 6.0 0.5 0.0 43.0 0.0 1.9 41.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 3.5 0.0 0.0 0.0 GAPVD1 "DKFZP434C212, KIAA1521" ENSG00000165219 "GTPase activating protein and VPS9 domains 1" Q14C86 9 125261794-125367207 "Predicted intracellular proteins" Endocytosis "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029386, HPA029387, HPA074882" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 46000 "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Cytosol "HPA029386: AB_10599604, HPA029387: AB_10600311, HPA074882: " "unprognostic (8.43e-3)" "unprognostic (3.84e-2)" "unprognostic (3.53e-1)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (4.04e-2)" "unprognostic (7.08e-2)" "unprognostic (1.31e-2)" "unprognostic (7.56e-2)" "unprognostic (1.23e-1)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "unprognostic (2.54e-3)" "unprognostic (2.77e-1)" "unprognostic (4.19e-2)" "unprognostic (1.67e-2)" "unprognostic (5.82e-2)" 12.3 9.8 8.1 12.2 11.1 23.0 12.0 11.7 9.4 12.2 13.1 10.3 8.0 11.1 9.8 17.0 10.7 10.3 9.7 8.4 8.8 13.0 11.2 15.7 12.6 9.8 8.9 12.1 10.6 18.7 8.2 18.4 10.0 10.5 9.8 16.5 9.3 12.4 19.1 14.7 9.2 13.3 10.1 12.7 9.6 26.8 9.7 14.1 18.9 18.7 15.0 12.2 10.1 14.2 22.8 23.2 21.8 20.0 26.2 28.6 30.5 25.0 28.9 29.0 24.2 37.0 15.9 30.2 13.3 31.9 28.7 44.9 46.2 25.8 31.1 28.1 27.1 34.6 53.1 18.4 30.1 41.4 56.0 20.1 25.2 34.6 27.2 18.7 35.0 23.8 68.8 16.3 24.3 33.2 31.2 18.0 21.6 41.2 26.2 27.2 47.6 29.1 16.2 23.2 28.8 18.9 36.9 32.6 20.0 21.7 40.9 20.9 36.1 19.9 14.3 35.7 27.2 20.7 42.3 29.9 24.1 22.9 26.4 25.6 15.9 19.6 13.0 15.4 12.7 10.0 13.5 14.6 15.4 9.5 13.3 14.3 19.5 15.2 19.8 5.8 11.8 11.3 8.1 11.1 11.7 9.4 8.4 8.8 9.8 8.9 10.0 10.1 9.7 14.2 30.0 109.0 58.0 35.6 28.3 31.9 18.2 23.0 32.5 29.9 21.0 17.5 66.8 14.3 34.8 27.6 52.1 42.3 20.7 16.6 9.8 16.2 58.3 35.7 30.7 26.8 12.6 77.0 68.4 19.3 23.7 26.2 18.3 31.4 15.8 27.6 21.4 15.2 27.6 35.3 69.7 15.9 10.2 25.4 28.5 17.7 23.0 30.5 17.8 51.5 31.2 22.8 18.6 45.2 62.7 22.3 13.9 24.0 26.5 20.0 15.4 16.1 57.2 39.1 19.7 27.8 32.0 85.6 34.5 32.3 36.9 67.0 28.3 32.5 17.0 29.8 GAS2 ENSG00000148935 "Growth arrest specific 2" O43903 11 22625509-22813055 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Cell shape, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "liver: 39.7" "Group enriched" "Detected in some" 4 "Astrocytes: 39.8;Excitatory neurons: 114.9;Inhibitory neurons: 141.9;Oligodendrocytes: 83.9" "Cancer enhanced" "Detected in many" "liver cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "Hep G2: 43.2;JURKAT: 24.0;Karpas-707: 85.2;SCLC-21H: 24.8;U-266/84: 30.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058904 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" Yes NA "Cluster 30: Non-specific - Translation" "Cluster 85: Liver - Metabolism" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "HPA058904: AB_2683850" "unprognostic (5.48e-3)" "unprognostic (1.00e-1)" "unprognostic (6.85e-2)" "unprognostic (1.16e-2)" "unprognostic (7.87e-2)" "unprognostic (2.08e-2)" "unprognostic (1.08e-1)" "unprognostic (1.49e-1)" "unprognostic (1.23e-1)" "unprognostic (3.71e-2)" "unprognostic (1.70e-2)" "unprognostic (3.30e-5)" "prognostic favorable (6.13e-4)" "unprognostic (5.85e-2)" "unprognostic (4.22e-2)" "unprognostic (7.94e-2)" "unprognostic (3.58e-2)" 0.4 0.8 2.1 0.3 1.9 0.1 0.8 4.5 5.4 0.9 0.0 0.7 1.8 0.8 0.0 0.7 1.2 1.6 3.5 0.7 2.2 5.4 39.7 1.0 1.0 6.2 7.5 2.0 9.6 0.1 2.5 0.4 6.3 1.0 0.4 2.2 1.5 0.6 4.6 0.8 1.6 0.3 3.3 1.3 2.6 0.8 6.1 8.2 0.8 1.8 0.7 1.0 0.7 6.1 0.0 0.1 1.7 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.0 0.1 1.7 0.4 0.2 0.0 43.2 0.5 0.1 0.3 0.1 0.1 0.0 0.2 0.3 0.0 24.0 1.6 85.2 0.0 0.4 0.3 0.1 0.3 2.4 0.0 0.9 0.5 4.4 0.0 1.1 24.8 1.3 0.0 0.0 0.5 0.2 0.1 0.0 1.8 0.0 0.4 1.1 0.0 1.1 30.7 0.0 0.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.1 1.9 4.5 5.4 0.7 2.2 6.2 7.5 6.3 3.3 6.1 6.1 0.1 0.0 0.0 39.8 0.4 0.1 0.4 0.1 0.6 1.9 0.4 0.1 12.7 10.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 2.3 1.3 0.1 0.4 0.0 0.0 114.9 3.3 0.0 1.0 3.1 0.7 0.0 0.2 0.7 22.9 0.0 0.0 141.9 0.6 0.0 0.0 0.0 5.4 0.6 0.0 0.0 9.4 0.2 0.2 0.0 18.6 83.9 1.6 1.4 0.0 0.5 0.1 0.1 3.2 4.0 1.2 0.0 0.3 0.8 0.4 1.1 0.6 0.0 0.0 0.4 0.1 0.9 0.3 GAS2L1 GAR22 ENSG00000185340 "Growth arrest specific 2 like 1" Q99501 22 29306582-29312785 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 84.6;Late spermatids: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 77.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019858 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Cell Junctions" "HPA019858: AB_1849486" "unprognostic (3.66e-1)" "unprognostic (5.22e-2)" "unprognostic (1.38e-1)" "unprognostic (4.95e-3)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-3)" "unprognostic (8.99e-2)" "unprognostic (1.28e-1)" "unprognostic (6.05e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "prognostic favorable (8.44e-4)" "unprognostic (4.23e-2)" "unprognostic (9.04e-2)" "unprognostic (1.32e-1)" "unprognostic (1.19e-2)" 22.6 36.3 46.7 5.5 41.8 6.5 22.4 39.4 58.5 16.2 30.4 25.8 18.1 18.4 5.3 34.3 16.5 4.2 33.5 45.4 37.8 21.0 18.6 19.3 2.3 50.0 43.3 8.9 14.4 6.6 22.1 4.1 42.2 22.2 2.0 4.0 24.7 16.9 6.5 52.8 17.8 4.4 41.8 29.1 27.4 51.3 47.3 1.1 15.6 3.9 1.8 17.6 19.6 37.4 20.4 23.1 3.5 14.5 5.5 5.2 22.6 29.7 8.9 12.3 6.4 10.6 14.2 0.1 13.1 15.9 12.9 60.5 6.0 16.8 2.2 27.6 2.9 26.5 19.9 7.5 7.0 0.2 17.8 5.6 11.5 11.9 4.7 8.9 16.5 26.2 12.8 4.1 9.0 17.2 0.5 14.8 5.3 13.5 51.6 0.6 10.3 1.7 7.5 12.8 1.2 19.0 23.0 30.3 17.0 4.4 30.2 4.1 35.5 77.0 53.0 34.6 30.3 0.3 0.4 0.3 34.1 1.0 19.3 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 46.7 41.8 39.4 58.5 45.4 37.8 50.0 43.3 42.2 41.8 47.3 37.4 34.5 6.4 1.7 28.1 0.4 28.2 7.0 12.3 21.6 3.6 24.0 18.4 5.6 14.3 8.3 1.8 6.2 24.8 0.8 13.4 7.9 12.2 33.8 19.2 9.2 26.2 1.8 19.6 14.8 6.7 14.3 12.0 9.2 10.0 1.3 28.9 84.6 12.0 14.1 13.5 11.4 5.1 20.3 14.5 23.0 89.7 9.6 37.6 12.4 7.5 7.6 5.4 0.0 4.0 4.0 10.2 7.2 11.7 0.2 6.1 41.7 10.1 4.3 20.9 39.5 35.3 23.5 5.4 12.4 27.9 32.4 6.7 2.2 17.8 11.8 4.6 GAS7 "KIAA0394, MGC1348" ENSG00000007237 "Growth arrest specific 7" O60861 17 9910606-10198606 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.6;Fibroblasts: 79.6;Inhibitory neurons: 76.6;Late spermatids: 73.4;Oligodendrocytes: 163.3" "Group enriched" "Detected in all" 4 "glioma: 15.7;melanoma: 54.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 26.2" "Group enriched" "Detected in many" 4 "granulocytes: 17.1;monocytes: 26.2" "Cell line enriched" "Detected in many" 9 "WM-115: 533.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004838, HPA064678" Enhanced Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA004838: AB_2667263, HPA064678: AB_2685319" "unprognostic (1.68e-2)" "unprognostic (2.84e-3)" "unprognostic (1.80e-1)" "unprognostic (1.28e-3)" "unprognostic (1.15e-1)" "unprognostic (1.01e-2)" "unprognostic (7.32e-2)" "unprognostic (7.16e-2)" "unprognostic (2.88e-1)" "unprognostic (1.50e-2)" "unprognostic (2.48e-1)" "unprognostic (1.79e-1)" "unprognostic (1.94e-3)" "unprognostic (6.48e-2)" "unprognostic (8.78e-2)" "unprognostic (3.08e-2)" "prognostic unfavorable (6.89e-4)" 27.3 8.5 34.9 23.7 68.9 31.1 15.3 75.4 79.8 29.9 0.0 26.3 7.3 13.3 4.3 23.8 17.8 16.3 46.1 61.9 8.4 1.7 2.3 17.1 9.1 23.4 24.1 7.8 3.4 1.1 2.6 16.2 15.8 8.5 12.0 30.1 7.8 10.8 5.8 33.7 11.9 24.0 14.3 16.1 8.9 17.4 32.9 9.3 4.6 6.8 10.3 18.3 19.5 85.3 0.1 0.5 0.6 1.0 16.5 22.5 0.3 0.8 0.0 2.6 1.1 0.1 0.2 6.6 1.9 6.6 0.3 0.3 0.0 0.0 1.6 0.0 1.5 0.0 1.3 0.7 5.3 1.8 48.7 4.3 0.3 5.1 0.1 0.0 0.0 42.7 0.0 0.6 0.0 0.0 54.3 15.4 2.6 2.1 0.0 14.3 0.1 49.6 0.0 0.2 0.1 3.0 0.2 0.2 60.1 21.0 2.8 24.7 0.0 0.2 3.4 0.1 0.1 0.4 0.0 0.0 0.4 35.1 533.8 0.6 26.2 17.1 2.8 6.9 0.9 0.5 0.3 1.4 5.3 0.6 0.2 1.4 16.4 4.5 4.9 1.0 0.0 7.7 34.9 68.9 75.4 79.8 61.9 8.4 23.4 24.1 15.8 14.3 32.9 85.3 2.9 0.0 4.2 6.8 3.3 8.3 4.5 1.5 1.2 34.6 1.6 2.3 13.3 0.0 1.1 5.5 27.1 1.0 14.5 0.0 0.0 1.0 62.3 17.7 12.8 5.7 0.0 0.4 133.6 0.0 1.8 79.6 0.0 26.3 17.2 7.9 5.0 0.9 39.2 0.0 76.6 0.0 0.0 66.7 32.2 73.4 10.2 54.3 33.8 52.5 57.2 9.5 18.6 11.1 163.3 0.2 0.0 1.9 5.5 2.0 0.0 0.1 16.3 31.7 0.0 67.0 7.1 1.6 6.7 1.0 16.6 1.9 7.4 0.2 0.0 4.9 GAS8 "DRC4, GAS11" ENSG00000141013 "Growth arrest specific 8" O95995 16 90019629-90044975 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 198.3;Late spermatids: 277.8;Respiratory ciliated cells: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041311, HPA048238" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Cytosol "Plasma membrane" "HPA041311: AB_2677402, HPA048238: AB_2680324" "unprognostic (2.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.73e-1)" "unprognostic (3.91e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (4.47e-1)" "prognostic favorable (7.67e-4)" "unprognostic (3.06e-2)" "prognostic favorable (1.09e-7)" "unprognostic (1.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.19e-2)" 5.2 10.3 9.5 2.8 9.7 1.4 6.3 10.0 14.3 7.8 12.3 7.7 2.6 6.5 10.1 8.4 18.9 6.1 15.4 9.5 9.9 13.8 5.5 7.1 2.8 10.3 10.0 8.9 10.5 16.3 14.1 2.1 10.1 7.3 3.0 5.0 11.4 8.6 15.1 4.5 3.9 4.4 10.3 3.4 8.2 16.8 10.9 2.5 12.5 10.0 2.0 6.3 5.8 10.2 17.9 14.5 1.8 8.5 7.8 6.2 14.3 3.6 8.8 13.9 4.1 14.1 13.0 1.0 9.1 7.1 8.4 17.8 5.9 9.9 3.3 0.0 10.7 3.7 9.0 16.2 8.7 2.2 2.8 7.9 6.0 10.4 4.7 6.3 8.3 5.8 14.3 2.1 6.1 41.9 2.5 9.9 11.6 11.3 7.4 0.7 15.7 1.0 17.4 8.5 14.6 10.7 18.4 9.7 21.0 1.6 19.6 8.4 6.2 8.6 10.3 4.7 8.3 3.4 5.4 0.0 21.3 2.7 15.1 1.7 1.2 1.4 0.7 2.0 0.7 0.4 1.0 1.4 1.7 0.8 0.8 0.7 1.5 0.0 1.3 1.9 1.6 0.8 9.5 9.7 10.0 14.3 9.5 9.9 10.3 10.0 10.1 10.3 10.9 10.2 5.9 22.4 11.3 20.5 3.1 1.1 4.7 7.0 5.7 11.9 14.1 10.8 7.9 25.8 13.4 22.0 20.9 3.0 0.7 5.9 13.7 17.1 198.3 45.5 7.1 5.8 6.0 3.0 27.5 10.9 3.6 5.5 12.2 10.0 2.5 16.1 7.1 4.8 4.1 26.9 24.6 6.3 8.2 0.8 1.4 277.8 14.0 2.3 5.4 1.9 1.3 12.4 0.0 13.0 6.0 10.0 4.6 7.5 1.1 5.8 5.3 30.9 82.3 28.0 6.6 6.7 9.5 28.7 11.9 7.2 2.6 1.6 1.6 25.2 5.3 5.8 GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.4;Endothelial cells: 81.2;Hepatic stellate cells: 92.4;Theca cells: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;HDLM-2: 9.9;HEL: 13.0;REH: 11.1;RT4: 18.3;U-266/70: 16.0" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Plasma membrane" "HPA030101: AB_10601654, HPA062039: " "unprognostic (1.32e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.07e-3)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "unprognostic (5.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "prognostic favorable (9.29e-5)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.02e-3)" 11.3 5.2 4.0 29.5 3.9 6.6 6.7 4.4 4.8 4.2 2.6 6.6 12.4 8.8 4.5 7.2 9.1 8.8 11.0 3.8 4.3 9.8 14.1 31.2 34.3 7.1 3.7 16.4 1.6 6.5 2.7 11.9 7.7 5.8 7.2 3.4 7.1 6.7 7.1 2.1 11.8 7.7 3.9 29.0 11.9 2.9 4.4 10.0 7.8 9.4 11.0 13.1 4.5 3.9 0.8 0.0 0.1 0.3 0.1 0.1 0.6 1.8 7.6 8.0 7.2 0.1 12.1 0.6 1.0 2.3 0.6 0.9 0.0 0.3 0.4 9.9 0.1 13.0 0.4 0.3 1.0 0.2 0.3 0.4 0.0 0.1 0.0 1.2 1.9 0.3 0.4 2.3 0.0 0.2 6.6 0.3 0.4 0.1 0.1 11.1 0.2 0.4 0.1 18.3 0.2 0.5 0.3 0.7 0.3 0.6 0.5 1.4 0.4 0.3 1.6 0.2 0.2 16.0 0.3 0.3 0.3 0.1 2.3 0.6 4.1 0.4 7.1 14.1 6.1 2.5 7.6 7.9 2.2 3.3 5.6 5.2 5.6 13.8 14.5 0.9 9.0 5.5 4.0 3.9 4.4 4.8 3.8 4.3 7.1 3.7 7.7 3.9 4.4 3.9 84.4 32.1 39.3 0.0 28.3 4.6 9.1 20.7 1.8 2.8 3.5 2.4 3.6 8.6 25.3 5.5 8.4 0.9 29.0 5.1 0.0 2.2 1.9 4.8 8.4 81.2 0.0 11.2 0.5 3.3 1.6 22.2 9.2 7.4 21.5 17.9 92.4 6.5 8.3 0.0 2.5 4.3 4.1 29.2 10.9 1.2 3.7 33.7 5.4 15.9 33.8 15.5 36.0 1.0 0.6 36.3 1.9 1.9 7.2 24.4 4.4 1.5 43.3 12.2 0.0 5.3 11.3 2.4 3.4 2.9 3.0 1.5 34.2 122.6 2.4 13.6 GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in all" "Early spermatids: 185.0;Kupffer cells: 183.3;Macrophages: 153.5;monocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" 30.5 13.5 16.4 62.6 23.0 325.7 17.6 20.2 28.8 12.2 11.4 18.0 19.3 9.8 24.6 10.9 16.2 23.0 9.7 15.9 17.7 18.3 15.0 26.5 33.0 25.5 20.7 8.5 16.6 10.4 8.2 25.2 23.6 12.2 19.6 10.6 12.3 9.7 2.7 7.0 18.7 18.8 21.6 70.1 25.1 24.1 19.5 18.4 17.0 14.9 25.4 26.1 5.7 37.3 2.6 4.2 10.7 0.0 2.5 2.2 0.4 4.0 11.1 6.2 11.1 8.7 30.6 3.7 27.0 0.3 14.2 1.6 4.1 12.7 7.7 17.1 16.8 33.5 2.9 17.7 3.0 41.6 9.1 2.8 4.3 5.7 1.2 15.8 0.9 25.9 0.6 12.1 0.5 33.0 0.9 24.2 6.5 22.5 16.4 14.2 2.7 18.5 32.7 18.6 6.9 12.0 5.1 23.3 19.7 12.5 15.8 17.7 0.8 1.6 11.2 17.8 6.2 11.5 23.2 0.6 9.2 15.8 7.7 38.8 132.4 327.4 2.7 78.4 3.5 21.6 4.8 4.8 63.2 21.1 8.1 5.0 864.2 2.5 63.3 17.2 10.2 71.4 16.4 23.0 20.2 28.8 15.9 17.7 25.5 20.7 23.6 21.6 19.5 37.3 28.8 16.0 36.5 10.1 54.5 15.4 28.2 19.6 12.5 10.2 32.6 16.4 4.1 50.1 21.2 33.1 2.1 55.5 17.3 14.4 76.3 49.5 185.0 21.1 9.1 26.4 39.4 36.1 25.9 60.5 20.8 14.4 43.8 24.9 44.9 13.6 48.9 15.0 107.9 11.8 15.4 29.9 32.6 183.3 60.5 32.8 10.8 153.5 16.0 17.8 228.5 21.1 10.3 1.0 98.0 36.5 25.7 6.4 23.4 24.3 18.4 69.7 24.7 4.4 6.6 12.2 18.3 52.6 13.5 15.1 18.2 46.9 16.3 16.7 28.9 21.0 GCC1 "FLJ22035, GCC1P, GCC88, MGC20706" ENSG00000179562 "GRIP and coiled-coil domain containing 1" Q96CN9 7 127580628-127593611 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 9 "Early spermatids: 102.7;Late spermatids: 131.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019369, HPA021323" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA019369: AB_1849552, HPA021323: AB_1849554" "unprognostic (1.09e-1)" "unprognostic (4.96e-2)" "unprognostic (1.83e-1)" "unprognostic (9.51e-2)" "unprognostic (1.07e-1)" "unprognostic (7.20e-2)" "unprognostic (1.26e-1)" "unprognostic (2.54e-2)" "unprognostic (1.83e-1)" "unprognostic (5.08e-2)" "unprognostic (4.81e-2)" "unprognostic (4.50e-3)" "unprognostic (1.17e-3)" "unprognostic (4.17e-3)" "unprognostic (1.22e-1)" "unprognostic (8.65e-2)" "unprognostic (9.96e-2)" 6.6 6.6 5.4 7.8 6.3 13.5 9.2 6.4 5.7 7.0 6.2 6.9 6.5 6.1 6.5 7.0 5.9 6.3 4.8 5.2 5.9 6.2 10.6 6.9 8.6 6.3 6.3 8.0 6.9 9.4 4.5 7.5 6.1 7.3 6.2 3.6 8.2 6.7 6.6 7.8 6.5 5.1 6.2 8.3 7.7 11.0 6.1 8.3 7.7 6.7 9.9 7.1 4.7 7.2 15.7 20.8 9.0 19.5 19.7 13.5 12.4 13.4 15.5 13.2 16.5 17.5 10.5 14.4 8.0 12.6 29.7 17.0 13.1 14.7 14.1 20.3 11.9 10.6 11.4 9.2 29.2 18.5 16.9 12.7 39.7 14.1 27.8 12.4 12.6 14.2 17.6 16.1 15.0 15.6 18.0 16.0 18.8 17.2 16.1 12.7 9.8 16.5 11.4 12.0 14.2 20.6 14.4 67.9 27.5 16.1 11.6 13.2 16.4 19.5 6.3 17.0 15.6 43.6 20.6 9.1 19.3 18.6 20.2 5.3 7.1 13.2 7.1 6.9 9.1 6.6 6.4 7.0 6.6 6.3 5.1 5.2 13.1 8.7 8.2 3.8 6.5 8.1 5.4 6.3 6.4 5.7 5.2 5.9 6.3 6.3 6.1 6.2 6.1 7.2 4.8 12.8 7.7 0.0 9.6 10.6 5.0 2.7 12.0 4.1 11.5 6.1 3.6 4.3 3.7 3.7 4.2 7.2 7.3 10.0 5.9 5.1 102.7 4.3 5.5 6.7 7.2 8.2 0.0 6.4 4.6 5.0 8.6 6.8 1.3 5.9 5.0 7.4 5.2 11.8 0.0 8.2 2.0 10.1 8.3 131.7 5.3 7.6 12.4 0.0 6.9 4.9 5.2 0.0 0.0 5.9 6.6 3.8 6.3 5.4 6.0 4.5 2.4 5.9 6.6 5.9 6.5 7.8 4.6 6.3 10.4 10.4 8.8 5.8 5.8 5.4 GCLM GLCLR ENSG00000023909 "Glutamate-cysteine ligase modifier subunit" P48507 1 93885199-93909456 "Cancer-related genes, Metabolic proteins, Predicted intracellular proteins" "Glutathione biosynthesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 48.5" "Group enriched" "Detected in many" 4 "Basal prostatic cells: 207.9;Erythroid cells: 301.9;Prostatic glandular cells: 762.3;Urothelial cells: 374.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009568, HPA023696, CAB040554" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1100000 "Cluster 15: NK-cells - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009568: AB_2107835, CAB040554: , HPA023696: AB_1849560" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (8.85e-3)" "unprognostic (1.56e-2)" "unprognostic (2.83e-2)" "unprognostic (4.64e-2)" "prognostic unfavorable (9.83e-6)" "unprognostic (2.37e-1)" "unprognostic (1.07e-1)" "unprognostic (3.53e-1)" "unprognostic (3.51e-2)" "unprognostic (3.89e-2)" "unprognostic (2.19e-2)" "unprognostic (1.09e-2)" "unprognostic (1.79e-1)" "unprognostic (2.43e-1)" "unprognostic (2.34e-3)" 12.2 13.1 5.4 6.6 4.7 15.0 6.6 5.1 5.4 4.5 5.6 6.2 19.2 3.6 4.0 6.6 14.3 14.1 4.7 4.7 7.5 11.3 48.5 5.9 4.6 6.4 6.9 2.8 7.7 6.7 3.4 10.3 7.1 5.6 5.5 3.6 4.5 5.9 16.0 3.0 12.7 3.6 5.1 6.8 5.7 3.2 5.7 5.0 16.8 11.8 10.1 6.9 3.7 6.1 37.7 58.6 6.4 12.6 20.9 13.0 24.4 43.7 27.3 32.8 24.3 9.9 21.7 14.2 84.8 28.8 106.7 37.3 9.6 18.0 26.2 38.6 12.7 98.9 37.4 42.8 39.1 36.8 15.2 16.1 6.7 67.0 10.7 13.2 36.4 16.0 40.0 20.5 24.0 7.3 26.8 8.5 21.5 36.0 27.4 12.3 19.0 20.9 23.6 43.4 14.8 6.1 41.3 32.2 15.4 71.8 7.2 22.7 38.4 34.1 20.1 64.5 66.7 18.1 25.0 14.7 28.2 20.4 12.2 2.1 0.3 0.7 2.6 0.2 1.5 1.3 2.5 3.4 0.3 2.0 1.5 1.6 1.5 2.3 0.3 1.0 0.7 0.7 5.4 4.7 5.1 5.4 4.7 7.5 6.4 6.9 7.1 5.1 5.7 6.1 28.7 41.7 19.1 16.0 14.6 11.5 207.9 33.2 24.5 24.8 24.2 34.2 16.4 61.5 29.0 29.5 6.2 63.5 39.3 21.7 25.4 25.1 3.9 66.3 27.6 55.5 52.5 301.9 32.0 12.3 19.6 44.5 15.8 50.1 19.7 17.3 31.4 102.4 19.9 33.7 30.7 19.9 22.4 20.7 51.4 4.0 21.5 32.0 8.8 15.0 9.3 21.2 34.0 11.1 11.6 24.2 8.0 12.4 21.6 762.3 47.2 65.1 64.3 13.1 0.0 48.4 37.1 32.0 36.7 33.5 9.2 45.0 34.1 26.5 17.8 374.9 GDE1 MIR16 ENSG00000006007 "Glycerophosphodiester phosphodiesterase 1" Q9NZC3 16 19501693-19522123 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 270.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077420 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Nucleoplasm, Plasma membrane" "HPA077420: " "unprognostic (1.69e-1)" "unprognostic (5.13e-2)" "prognostic favorable (3.12e-4)" "unprognostic (1.47e-1)" "unprognostic (1.83e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (7.52e-5)" "unprognostic (2.10e-2)" "unprognostic (1.40e-2)" "unprognostic (4.31e-2)" "unprognostic (2.60e-3)" "unprognostic (9.92e-2)" "prognostic favorable (3.12e-5)" "unprognostic (8.36e-2)" "unprognostic (9.69e-3)" "unprognostic (1.88e-1)" "unprognostic (3.36e-2)" 28.9 25.9 42.9 15.6 46.3 27.8 21.1 42.9 49.9 21.9 40.4 44.9 30.0 20.0 27.5 22.4 16.9 18.4 52.8 45.7 45.5 27.6 25.4 29.3 11.7 44.5 47.7 12.8 28.5 76.8 19.2 20.5 43.3 26.7 41.6 19.8 28.3 30.3 62.9 26.4 27.7 26.5 42.8 13.5 34.3 14.1 48.8 16.8 20.3 64.4 15.3 30.2 16.6 47.4 38.6 46.2 25.0 29.4 115.3 43.3 34.7 38.3 66.9 30.0 37.1 26.6 67.4 29.2 48.1 57.2 32.8 31.8 35.2 46.6 36.9 31.7 52.8 24.2 41.4 57.2 69.1 32.7 21.5 44.9 73.1 32.2 37.4 54.5 40.6 36.3 13.7 29.1 33.2 70.3 28.3 29.1 29.1 59.9 34.2 40.2 45.7 41.7 72.9 59.7 28.9 25.8 37.0 44.5 37.9 38.5 45.8 37.8 42.7 25.3 22.3 33.9 24.6 27.0 27.4 19.9 38.5 47.2 23.1 52.0 19.3 11.2 8.9 17.7 11.5 7.2 10.4 10.4 12.4 6.1 5.5 8.5 34.0 6.6 22.7 7.5 12.7 8.2 42.9 46.3 42.9 49.9 45.7 45.5 44.5 47.7 43.3 42.8 48.8 47.4 12.2 38.5 86.8 7.2 18.9 23.5 30.3 56.2 22.8 15.4 38.3 22.4 66.8 34.3 56.0 9.2 27.1 80.4 23.2 123.1 23.5 97.0 35.1 26.9 23.8 17.7 33.5 100.8 12.0 163.9 78.6 27.3 24.5 21.5 3.8 36.4 20.7 23.9 60.8 32.0 15.9 57.5 61.1 48.2 22.9 61.2 28.6 32.3 24.9 8.4 38.2 22.3 24.7 9.5 25.0 77.4 97.6 38.0 19.6 100.5 101.7 45.9 39.7 29.6 13.1 16.7 24.9 87.1 59.6 31.9 29.5 270.4 22.0 45.9 85.3 79.2 GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 39.0" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 99.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "basophil: 195.6;eosinophil: 395.8" "Lineage enriched" "Detected in many" 26 "granulocytes: 395.8" "Group enriched" "Detected in some" 5 "HEL: 168.9;HMC-1: 104.6;K-562: 53.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004420: AB_2110132, HPA006291: " "unprognostic (1.79e-2)" "unprognostic (2.90e-4)" "unprognostic (6.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-2)" "unprognostic (2.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.54e-1)" "unprognostic (4.61e-2)" "unprognostic (3.71e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-2)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.3 0.1 39.0 0.0 0.2 0.2 0.0 0.2 0.5 0.9 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.0 0.2 1.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.1 0.1 0.4 0.5 1.0 0.1 0.1 1.8 0.3 2.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.9 0.3 23.8 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 168.9 0.2 0.1 0.0 0.1 104.6 0.0 1.4 0.0 0.2 0.0 0.0 0.0 53.0 0.2 0.0 0.0 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 195.6 0.3 395.8 0.1 1.9 0.1 0.1 0.1 0.0 1.9 0.2 0.5 0.1 3.9 0.5 15.1 1.0 0.0 12.5 0.0 0.1 0.2 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.4 0.2 0.0 0.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.8 0.0 0.0 0.1 0.1 0.8 0.0 0.1 3.8 0.0 0.3 0.4 1.2 99.1 0.4 0.0 0.2 0.3 0.0 0.1 14.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.0 12.9 0.0 15.8 0.0 0.0 0.6 0.0 0.0 0.5 0.2 0.0 24.2 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.3 0.2 1.0 0.6 0.1 GFOD1 "ADG-90, C6orf114, FLJ20330" ENSG00000145990 "Glucose-fructose oxidoreductase domain containing 1" Q9NXC2 6 13357830-13487662 "Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.1" "Cell type enhanced" "Detected in many" "Adipocytes: 100.9;Cardiomyocytes: 108.2;Excitatory neurons: 133.2;Inhibitory neurons: 106.2;NK-cells: 142.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 15.5;NK-cell: 13.1" "Group enriched" "Detected in many" 5 "granulocytes: 15.5;NK-cells: 13.1" "Cell line enhanced" "Detected in many" "HEL: 30.5;HMC-1: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029096 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted - unknown location" No No "Cluster 49: Eosinophils - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029096: AB_10602320" "unprognostic (5.00e-2)" "unprognostic (1.34e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (2.29e-5)" "unprognostic (8.49e-2)" "unprognostic (1.95e-3)" "unprognostic (1.36e-2)" "unprognostic (2.81e-1)" "unprognostic (2.34e-2)" "unprognostic (3.11e-2)" "unprognostic (6.49e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (6.72e-5)" "unprognostic (9.79e-2)" "unprognostic (1.61e-1)" "unprognostic (3.56e-1)" "unprognostic (4.66e-3)" 10.5 2.0 14.3 2.8 21.6 12.7 9.6 11.2 26.1 5.0 0.0 6.2 1.8 3.6 0.8 8.6 4.4 4.3 16.7 24.5 3.7 2.3 7.2 9.7 4.3 3.0 1.5 1.5 1.5 1.7 3.5 3.9 2.3 4.0 2.8 2.1 3.6 1.4 12.0 5.5 6.5 4.9 0.6 8.8 7.9 0.6 2.5 3.0 2.7 9.7 4.2 6.2 5.8 16.9 12.5 1.3 1.0 2.1 1.7 1.8 1.3 1.0 0.5 0.7 0.4 0.4 0.9 16.8 16.6 1.2 1.0 10.9 3.4 5.4 0.7 1.2 6.0 30.5 7.2 6.6 2.4 9.0 46.3 0.9 4.1 1.6 4.5 2.6 9.5 4.5 0.9 1.5 1.3 4.1 2.0 5.2 1.8 4.3 3.3 6.9 2.1 8.8 0.6 2.4 5.5 1.0 4.0 0.7 4.0 2.1 0.9 0.9 12.2 1.6 3.2 3.5 5.6 13.4 8.3 19.8 1.4 5.3 0.4 0.2 0.4 15.5 1.5 0.9 0.2 2.7 0.2 0.7 0.2 1.9 0.1 0.5 0.3 13.1 0.9 0.1 0.1 1.0 14.3 21.6 11.2 26.1 24.5 3.7 3.0 1.5 2.3 0.6 2.5 16.9 100.9 0.0 1.8 33.0 14.3 20.3 4.9 14.5 19.9 43.8 7.4 3.7 108.2 10.0 14.4 0.0 0.0 1.5 46.1 18.2 0.0 5.3 0.1 3.8 1.0 49.0 8.4 31.2 133.2 3.1 34.7 9.1 2.0 8.0 4.5 0.2 51.4 19.5 2.5 1.7 106.2 11.2 8.2 15.7 31.3 0.3 2.5 21.4 12.4 42.2 4.7 2.1 142.2 58.8 56.6 30.5 31.7 1.2 14.5 3.1 10.6 0.3 13.6 2.7 13.1 19.9 17.5 0.0 3.3 34.6 22.4 0.7 23.4 1.0 4.4 4.7 GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Enteroendocrine cells: 53.1;granulocytes: 26.7;Late spermatids: 20.9;Spermatogonia: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.9" "Region enriched" "Detected in single" 8 "cerebellum: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 32.0" "Not detected" "Not detected" HPA020731 Approved Uncertain "Plasma membrane,Cytosol" NA NA 150000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane" Cytosol "HPA020731: AB_1849635" "unprognostic (1.22e-1)" "unprognostic (6.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.47e-3)" "unprognostic (2.77e-3)" "unprognostic (1.27e-1)" "unprognostic (7.65e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-2)" "unprognostic (1.90e-5)" "unprognostic (2.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" 1.8 1.6 0.0 2.1 0.2 0.0 1.6 2.5 0.3 7.4 0.0 13.0 2.7 0.5 2.5 2.3 1.2 1.9 5.7 0.1 0.2 0.5 0.5 2.0 0.1 0.1 0.1 1.3 3.7 0.0 2.0 0.0 0.2 4.1 3.8 0.0 3.2 5.9 0.2 3.1 3.3 2.0 0.1 0.0 6.3 4.2 0.1 0.5 0.8 0.4 0.1 5.1 7.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.1 0.0 0.0 2.0 1.2 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 32.0 0.5 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 8.7 0.0 0.0 0.0 53.1 0.0 0.2 0.2 0.2 0.5 0.0 0.0 26.7 0.3 0.0 0.0 0.1 0.0 0.1 0.2 6.1 0.0 0.2 20.9 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.8 8.4 0.1 0.0 0.3 0.0 0.1 0.0 0.1 GFRAL "bA360D14.1, C6orf144, GRAL, UNQ9356" ENSG00000187871 "GDNF family receptor alpha like" Q6UXV0 6 55327469-55402493 "Predicted membrane proteins" Receptor "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047372 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "Actin filaments, Focal adhesion sites" "HPA047372: AB_2680017" "unprognostic (2.31e-1)" 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.3 0.3 0.3 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GHR GHBP ENSG00000112964 "Growth hormone receptor" P10912 5 42423439-42721878 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Endocytosis Receptor "Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 84.7;liver: 213.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 53.3;Hepatocytes: 141.3;Inhibitory neurons: 115.7;Oligodendrocyte precursor cells: 181.0" "Group enriched" "Detected in many" 4 "breast cancer: 2.8;liver cancer: 7.6;prostate cancer: 8.1;renal cancer: 2.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HSkMC: 21.2;T-47d: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045339, HPA057705" Enhanced Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" "Secreted to blood" NA NA 2200000 24000000 "Cluster 85: Liver - Metabolism" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol, Cytoplasmic bodies" "HPA045339: AB_2679294, HPA057705: AB_2683507" "unprognostic (2.18e-2)" "unprognostic (5.45e-2)" "unprognostic (1.63e-1)" "unprognostic (1.96e-2)" "unprognostic (3.12e-1)" "unprognostic (1.57e-1)" "prognostic favorable (2.73e-6)" "unprognostic (1.06e-1)" "unprognostic (3.92e-2)" "unprognostic (3.73e-2)" "unprognostic (6.15e-3)" "unprognostic (2.67e-2)" "unprognostic (1.67e-3)" "unprognostic (4.29e-4)" "unprognostic (7.82e-2)" "unprognostic (7.33e-4)" "unprognostic (8.35e-6)" 84.7 5.6 1.8 1.7 2.1 0.2 30.1 1.7 1.7 5.2 2.3 5.8 1.1 4.5 4.6 3.9 5.4 5.2 8.9 1.8 5.6 11.8 213.3 4.0 1.3 1.0 2.0 7.5 2.1 5.5 1.2 4.8 1.4 11.1 5.7 0.4 3.7 4.7 45.7 5.6 4.3 4.0 1.1 4.0 6.1 1.7 3.4 2.3 4.6 11.6 0.9 5.0 5.8 1.4 0.0 0.0 0.6 5.0 3.3 0.7 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.0 0.3 4.3 0.0 0.0 2.6 0.0 0.1 0.0 0.6 0.0 0.0 21.2 7.0 0.0 1.0 0.1 0.1 0.0 0.0 0.0 1.8 0.2 0.0 0.0 0.3 0.0 0.7 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.3 0.1 3.5 0.6 56.0 0.1 3.0 4.8 2.1 2.6 0.5 0.5 0.0 0.0 0.5 0.0 2.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.8 2.1 1.7 1.7 1.8 5.6 1.0 2.0 1.4 1.1 3.4 1.4 17.2 0.0 0.5 14.7 0.4 4.7 4.5 17.8 10.2 0.6 9.7 16.0 18.6 1.5 1.9 1.8 0.0 17.4 0.5 2.8 1.9 0.0 5.1 0.5 9.4 4.8 3.0 5.3 53.3 0.2 2.2 23.8 0.5 0.3 0.0 1.1 6.1 141.3 1.9 0.0 115.7 1.9 0.0 3.0 1.8 2.8 18.6 0.7 1.8 36.5 0.0 0.7 0.0 181.0 3.6 0.2 1.7 12.0 0.0 5.2 0.0 9.6 0.6 0.4 13.1 18.7 15.1 0.7 0.3 2.9 3.7 40.2 0.5 49.4 2.2 0.9 GID8 "bA305P22.1, C20orf11, FLJ20602, TWA1" ENSG00000101193 "GID complex subunit 8 homolog" Q9NWU2 20 62938147-62948475 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049929, HPA055047" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Cell Junctions" "HPA049929: AB_2680957, HPA055047: AB_2682682" "unprognostic (1.35e-1)" "unprognostic (4.06e-2)" "unprognostic (5.90e-2)" "prognostic unfavorable (4.78e-4)" "unprognostic (1.19e-1)" "unprognostic (8.25e-2)" "unprognostic (3.88e-2)" "unprognostic (4.58e-2)" "unprognostic (2.16e-1)" "unprognostic (1.83e-1)" "unprognostic (2.72e-2)" "unprognostic (1.43e-1)" "prognostic favorable (3.22e-4)" "unprognostic (3.97e-1)" "unprognostic (1.43e-1)" "unprognostic (2.01e-1)" "unprognostic (6.87e-2)" 12.5 13.3 18.8 13.5 18.3 39.2 17.1 18.7 18.3 19.1 16.7 16.6 13.8 16.3 16.8 41.8 20.1 11.1 14.2 19.2 18.6 17.2 24.7 12.7 20.7 17.8 18.4 26.3 20.4 19.0 15.9 13.0 17.4 16.2 14.3 13.0 17.1 14.8 14.8 30.5 15.5 12.5 18.8 16.9 18.1 13.7 19.2 25.3 18.4 13.2 23.1 15.6 22.5 18.3 39.9 25.0 36.6 33.2 29.5 23.1 35.8 21.8 18.2 61.1 27.5 121.4 37.9 49.9 36.5 28.4 25.1 45.2 33.9 45.3 36.9 13.4 16.6 46.5 32.8 58.6 23.2 54.5 37.7 25.6 49.4 26.4 30.4 22.2 30.1 32.5 36.3 21.0 21.3 56.0 65.3 48.4 37.0 66.1 37.0 51.1 68.8 29.9 22.5 55.4 38.0 31.0 51.5 49.9 32.8 27.0 69.5 51.9 30.6 36.4 45.4 28.8 29.9 21.9 27.0 51.2 24.6 26.2 23.5 5.3 9.5 15.4 9.8 8.3 11.6 7.4 10.4 11.1 8.9 8.2 11.2 12.7 13.5 12.3 7.7 6.7 9.9 8.1 18.8 18.3 18.7 18.3 19.2 18.6 17.8 18.4 17.4 18.8 19.2 18.3 33.5 19.2 27.4 11.4 42.7 51.6 46.9 76.6 50.1 23.1 56.4 53.0 30.9 52.9 46.5 40.5 6.2 101.7 48.6 57.3 41.1 44.7 19.1 46.4 27.4 37.7 45.0 71.1 17.7 40.4 105.1 35.1 27.0 40.1 26.6 24.4 46.4 77.7 51.8 16.8 15.0 50.1 50.8 47.9 46.4 19.4 32.9 42.9 24.9 11.2 62.1 28.3 51.5 11.6 14.4 40.8 39.2 42.2 44.0 68.2 55.7 42.5 38.8 16.5 13.1 34.1 30.7 49.1 57.9 82.1 79.8 156.9 45.8 21.6 52.1 71.7 GINM1 "C6orf72, dJ12G14.2" ENSG00000055211 "Glycoprotein integral membrane 1" Q9NU53 6 149566294-149591748 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017210, HPA041679" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 35000 "Cluster 19: B-cells - Humoral immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center, Plasma membrane" "HPA017210: AB_1845743, HPA041679: AB_2677611" "unprognostic (6.09e-3)" "unprognostic (2.19e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (7.24e-2)" "unprognostic (1.32e-3)" "unprognostic (3.18e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.64e-2)" "unprognostic (4.87e-2)" "unprognostic (4.79e-3)" 56.0 44.0 25.7 24.0 31.4 41.2 45.0 33.9 36.1 47.8 38.5 43.0 25.9 46.4 44.6 32.2 39.2 38.2 58.6 25.0 28.9 92.7 45.7 36.0 26.1 30.6 29.0 50.5 36.8 55.3 24.7 62.6 30.6 40.3 34.8 21.9 32.2 47.4 47.1 36.4 28.1 50.5 29.3 35.1 34.1 48.0 26.9 21.7 73.9 42.3 24.7 42.2 34.0 38.9 27.2 19.5 30.5 41.4 162.6 96.1 48.3 89.0 107.5 68.1 85.1 25.4 35.7 19.4 46.9 87.6 62.9 53.8 20.1 46.0 89.0 33.6 39.6 18.9 17.5 30.5 62.0 37.2 17.2 107.8 39.1 58.0 39.6 74.7 74.7 27.0 24.6 31.8 65.1 35.3 22.9 27.9 10.1 40.2 20.1 25.2 54.0 15.1 97.7 23.9 19.2 18.1 90.1 53.2 18.9 33.5 32.9 38.4 51.3 35.9 37.0 92.9 60.9 30.6 38.6 24.5 67.4 33.1 34.3 21.0 18.5 25.1 8.8 17.8 10.5 22.8 10.2 9.7 13.9 17.0 9.8 8.0 32.1 11.4 23.4 16.9 10.7 10.6 25.7 31.4 33.9 36.1 25.0 28.9 30.6 29.0 30.6 29.3 26.9 38.9 120.5 80.1 53.7 10.1 44.6 46.8 58.6 75.1 46.7 21.3 50.1 50.3 54.1 38.6 53.4 66.2 29.2 81.1 31.4 64.5 39.2 92.7 191.0 42.2 77.3 78.9 26.8 32.2 11.9 80.7 77.1 103.4 18.3 60.7 29.1 48.2 104.6 41.9 45.6 16.8 13.9 23.1 46.8 56.0 47.7 369.6 129.5 46.6 42.7 5.6 75.7 86.5 18.6 17.1 25.0 67.8 33.5 112.8 45.3 65.0 49.8 132.1 33.8 22.6 98.6 85.9 71.1 166.5 82.8 48.7 47.0 122.7 32.0 65.7 22.4 64.0 GIPC1 "C19orf3, GIPC, GLUT1CBP, Hs.6454, NIP, RGS19IP1, SEMCAP, SYNECTIN, TIP-2" ENSG00000123159 "GIPC PDZ domain containing family member 1" O14908 19 14477760-14496149 "Human disease related genes, Predicted intracellular proteins" "Congenital muscular dystrophy, Dystroglycanopathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 345.8" "Cell type enhanced" "Detected in all" "Distal enterocytes: 501.1;Pancreatic endocrine cells: 296.7;Paneth cells: 285.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043958, HPA061786" Approved Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 11000 "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA043958: AB_10963436, HPA061786: AB_2756319" "unprognostic (2.80e-1)" "unprognostic (1.16e-1)" "unprognostic (8.21e-2)" "unprognostic (1.03e-1)" "unprognostic (2.82e-1)" "unprognostic (1.07e-1)" "unprognostic (1.18e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (4.82e-2)" "unprognostic (3.53e-2)" "unprognostic (7.72e-2)" "unprognostic (1.04e-2)" "unprognostic (7.17e-3)" "unprognostic (1.70e-1)" "unprognostic (1.16e-1)" "unprognostic (8.82e-2)" 51.0 54.8 80.0 22.4 91.5 3.3 54.3 88.7 94.4 99.8 64.7 120.2 24.7 53.7 17.6 345.8 48.9 23.4 66.1 74.5 82.1 104.1 58.4 76.3 15.9 89.4 91.4 34.4 43.5 20.8 56.0 28.7 88.1 63.6 41.1 17.9 100.9 31.0 65.1 150.2 45.5 17.5 82.0 37.7 78.7 24.9 91.1 18.6 55.8 23.3 21.0 74.1 140.1 92.3 328.1 148.6 44.7 70.6 40.6 40.7 35.2 119.7 59.8 96.7 87.3 80.3 120.6 4.7 220.3 85.2 64.6 183.8 38.7 100.6 32.6 33.8 69.0 63.9 100.7 79.7 123.7 6.9 75.3 46.7 98.5 58.8 51.3 57.4 66.0 47.2 30.1 54.4 49.9 243.8 21.3 13.3 48.6 182.1 147.8 21.7 37.4 43.7 121.6 281.6 41.8 46.2 67.1 163.2 157.0 23.1 102.5 35.1 115.4 135.7 74.6 191.7 130.1 50.5 70.5 17.3 113.9 51.9 146.2 3.0 0.7 0.1 5.1 1.1 4.7 1.9 5.1 5.1 1.1 0.8 4.2 3.3 0.3 1.5 0.5 3.6 12.0 1.7 80.0 91.5 88.7 94.4 74.5 82.1 89.4 91.4 88.1 82.0 91.1 92.3 30.6 28.9 15.2 22.9 8.3 113.9 77.4 52.1 35.9 69.8 73.6 31.6 14.8 37.1 62.8 82.8 35.5 36.3 19.3 501.1 52.8 167.9 1.1 92.2 30.5 32.4 43.1 1.7 28.8 164.3 77.1 32.6 69.3 76.8 10.2 37.3 23.2 18.0 55.9 75.7 32.2 87.8 42.7 10.8 29.8 2.4 20.5 16.1 58.7 10.3 23.4 73.3 18.6 17.1 71.6 296.7 285.4 25.2 6.8 120.4 36.0 52.7 38.0 46.0 19.7 18.1 44.5 6.4 20.4 107.0 169.8 25.7 22.9 47.7 138.1 199.7 GJA1 "CX43, GJAL, ODD, ODDD, ODOD, SDTY3" ENSG00000152661 "Gap junction protein alpha 1" P17302 6 121435595-121449727 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted membrane proteins" "Cancer-related genes, Cataract, Disease variant, Hypotrichosis, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 250.0;Astrocytes: 276.2;Basal keratinocytes: 234.9;Cardiomyocytes: 199.7;Endometrial stromal cells: 215.5;Granulosa cells: 494.3;Suprabasal keratinocytes: 378.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 462.7;HUVEC TERT2: 362.3;NTERA-2: 365.8;SuSa: 453.4;U-87 MG: 350.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB010753, HPA035097, HPA047551, HPA069245" Enhanced Supported Supported "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" Nucleoplasm "CAB010753: AB_476857, HPA035097: AB_2674460, HPA047551: AB_2732540, HPA069245: " "unprognostic (3.37e-2)" "unprognostic (3.41e-3)" "unprognostic (2.95e-1)" "unprognostic (4.18e-2)" "unprognostic (1.48e-2)" "unprognostic (1.67e-2)" "unprognostic (1.27e-1)" "unprognostic (6.78e-2)" "unprognostic (2.89e-2)" "unprognostic (1.56e-1)" "unprognostic (5.47e-2)" "unprognostic (1.00e-1)" "unprognostic (4.88e-2)" "prognostic unfavorable (4.99e-5)" "unprognostic (2.39e-1)" "unprognostic (1.29e-1)" "unprognostic (3.00e-3)" 121.2 287.6 313.5 24.7 310.2 0.9 60.6 260.1 409.0 261.7 193.1 17.5 18.2 98.7 10.6 74.9 32.7 99.9 168.9 273.6 362.6 21.2 10.6 67.9 21.1 340.3 380.9 43.5 19.4 236.2 31.3 290.2 307.4 83.3 19.7 3.3 35.6 148.0 10.3 388.2 24.7 112.5 335.9 4.2 30.7 36.9 373.3 24.3 169.1 22.1 34.9 116.0 184.9 341.0 0.1 43.5 186.8 0.4 99.7 61.5 0.4 142.5 286.9 46.9 113.7 0.7 0.4 0.0 15.8 55.8 40.2 18.3 5.1 87.4 151.3 0.1 51.6 2.3 15.7 0.0 124.1 0.0 0.4 164.6 92.1 172.5 61.7 462.7 362.3 0.0 0.1 4.3 9.4 8.4 0.1 80.6 365.8 0.1 47.2 0.1 0.0 3.7 188.6 21.0 0.4 2.9 0.0 0.3 0.1 453.4 14.9 0.3 269.5 143.8 39.4 122.8 93.5 0.1 0.1 0.1 350.4 0.1 20.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 313.5 310.2 260.1 409.0 273.6 362.6 340.3 380.9 307.4 335.9 373.3 341.0 152.2 250.0 80.0 276.2 0.1 234.9 133.6 71.1 77.4 0.3 9.5 20.1 199.7 0.0 17.5 1.8 2.1 53.4 0.4 0.0 0.0 76.9 0.5 21.5 215.5 166.6 0.0 0.0 0.3 4.2 7.9 124.4 0.5 51.7 8.8 494.3 33.9 0.1 8.6 0.0 0.6 0.0 4.1 0.9 55.3 1.7 2.5 3.6 44.4 15.0 0.6 0.3 0.0 4.0 1.0 10.8 0.0 4.1 0.1 29.7 0.0 0.1 6.2 0.3 0.0 5.9 80.2 0.9 1.8 68.3 378.2 20.0 4.9 127.1 0.4 52.7 GJB3 "CX31, DFNA2, EKV" ENSG00000188910 "Gap junction protein beta 3" O75712 1 34781214-34786369 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Deafness, Disease variant, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 77.8;skin 1: 145.0" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 138.4;Basal prostatic cells: 71.9;Basal respiratory cells: 43.6;Pancreatic endocrine cells: 119.8;Prostatic glandular cells: 63.4;Squamous epithelial cells: 91.9;Suprabasal keratinocytes: 170.6;Urothelial cells: 171.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 58.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 88.8;CAPAN-2: 121.7;HaCaT: 99.4;HBEC3-KT: 84.9;hTCEpi: 136.8;OE19: 54.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074472 Supported "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cell Junctions" "HPA074472: AB_2686694" "unprognostic (1.34e-3)" "unprognostic (2.30e-1)" "unprognostic (2.84e-2)" "unprognostic (5.22e-3)" "unprognostic (3.82e-2)" "unprognostic (2.00e-2)" "unprognostic (1.21e-4)" "prognostic unfavorable (4.56e-4)" "unprognostic (2.30e-1)" "unprognostic (1.29e-1)" "prognostic unfavorable (7.56e-5)" "unprognostic (4.50e-2)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (1.22e-1)" "unprognostic (1.27e-2)" "unprognostic (2.46e-2)" 0.3 0.2 1.3 1.7 0.6 0.0 5.5 1.1 1.0 8.9 0.0 4.2 0.2 0.3 2.8 77.8 1.1 7.0 0.1 0.6 0.0 0.5 1.5 0.6 0.5 0.2 0.0 0.1 0.3 0.0 0.1 1.4 0.1 4.0 5.0 0.0 8.9 1.7 0.6 145.0 1.3 0.1 0.0 0.0 5.9 0.8 0.1 0.8 0.2 0.0 12.9 11.9 26.4 0.2 88.8 2.6 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 121.7 0.0 11.6 0.1 0.1 99.4 0.0 84.9 0.0 0.1 0.0 0.3 5.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 35.0 0.0 0.0 0.0 0.0 0.1 0.0 4.8 0.0 0.0 0.4 54.2 22.3 0.0 0.0 0.0 40.8 33.0 0.0 0.0 13.1 0.9 0.0 0.1 1.0 0.1 0.0 0.1 5.7 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.6 1.1 1.0 0.6 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 3.2 0.0 0.0 0.0 138.4 71.9 43.6 16.5 0.0 2.0 1.3 0.4 1.5 15.5 5.5 0.0 0.3 0.0 18.3 0.0 14.6 0.0 4.1 0.4 1.7 1.8 0.0 0.2 7.3 0.2 1.7 3.1 8.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.8 6.1 0.0 12.5 0.0 0.0 0.4 14.2 0.0 0.0 0.0 0.0 0.0 0.0 119.8 8.1 0.0 0.0 63.4 0.5 0.0 10.1 0.0 0.0 0.0 2.1 0.1 0.3 91.9 170.6 0.1 0.5 0.0 19.1 171.0 GJB4 CX30.3 ENSG00000189433 "Gap junction protein beta 4" Q9NTQ9 1 34759740-34762327 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "skin 1: 43.1" "Group enriched" "Detected in some" 4 "Basal prostatic cells: 31.1;Pancreatic endocrine cells: 37.0;Urothelial cells: 102.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.0;HaCaT: 12.2;HBEC3-KT: 8.3;hTCEpi: 5.7;OE19: 4.5;RPTEC TERT1: 4.8;RT4: 5.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA055112, HPA073904" Enhanced Supported "Cell Junctions" NA NA "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA055112: AB_2682699, HPA073904: " "unprognostic (3.30e-2)" "prognostic favorable (5.48e-4)" "unprognostic (1.57e-1)" "unprognostic (2.70e-2)" "unprognostic (4.21e-2)" "unprognostic (2.22e-1)" "unprognostic (2.16e-2)" "unprognostic (2.18e-2)" "unprognostic (5.40e-2)" "unprognostic (3.65e-1)" "prognostic unfavorable (3.24e-5)" "unprognostic (3.73e-2)" "unprognostic (5.81e-3)" "unprognostic (1.26e-1)" "unprognostic (1.67e-1)" "unprognostic (3.52e-4)" "unprognostic (5.42e-2)" 0.0 0.0 0.0 0.3 0.1 0.0 2.6 0.0 0.2 0.7 0.0 0.2 0.0 0.0 5.5 2.3 0.2 4.8 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.8 0.3 0.0 0.5 1.0 0.2 43.1 0.1 0.0 0.0 0.0 0.4 0.2 0.0 0.4 0.1 0.0 2.3 7.9 1.4 0.0 9.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.3 0.0 0.1 12.2 0.0 8.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 4.8 5.9 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 31.1 13.9 1.2 0.0 0.3 0.1 0.1 0.0 5.7 0.0 0.0 0.1 0.1 0.3 0.0 3.7 0.0 0.3 0.0 0.2 1.8 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 37.0 1.3 0.0 0.0 12.9 0.1 0.0 6.8 0.0 0.0 0.0 0.7 0.0 0.0 3.5 6.0 0.3 0.1 0.0 0.4 102.6 GJB6 "CX30, DFNA3, ED2, EDH, HED" ENSG00000121742 "Gap junction protein beta 6" O95452 13 20221962-20232365 "Disease related genes, Human disease related genes, Predicted membrane proteins" Hearing "Deafness, Disease variant, Ectodermal dysplasia, Non-syndromic deafness, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 95.6;esophagus: 195.4;vagina: 139.3" "Cell type enhanced" "Detected in some" "Astrocytes: 58.8;Basal keratinocytes: 12.2;Basal respiratory cells: 15.6;Ionocytes: 12.2;Squamous epithelial cells: 31.0" "Cancer enhanced" "Detected in many" "head and neck cancer: 145.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.6" "Lineage enriched" "Detected in single" 5 "T-cells: 2.6" "Cell line enriched" "Detected in some" 10 "RT4: 186.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014846 Supported "Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA014846: AB_1847135" "unprognostic (5.57e-2)" "unprognostic (1.20e-1)" "unprognostic (3.90e-4)" "unprognostic (7.90e-2)" "unprognostic (2.37e-1)" "unprognostic (1.69e-1)" "unprognostic (1.83e-1)" "unprognostic (8.96e-2)" "unprognostic (9.64e-2)" "unprognostic (2.82e-2)" "unprognostic (2.82e-2)" "unprognostic (3.54e-2)" "unprognostic (1.14e-11)" "unprognostic (8.99e-2)" "unprognostic (1.16e-1)" "unprognostic (6.35e-3)" "unprognostic (5.04e-2)" 0.5 0.2 55.8 0.3 59.4 95.6 3.8 73.0 80.9 65.9 36.0 0.0 0.0 0.9 0.2 195.4 0.4 1.3 0.1 50.2 63.5 0.0 0.1 0.3 0.8 60.0 71.8 0.0 0.1 0.0 4.4 0.0 57.5 0.2 0.1 0.0 34.5 0.0 0.1 56.8 0.2 0.0 47.7 0.2 0.3 1.4 76.3 37.6 5.3 0.0 15.4 10.3 139.3 42.7 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 4.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 0.0 0.0 186.3 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 1.1 0.6 0.5 0.0 0.0 0.0 2.6 0.2 55.8 59.4 73.0 80.9 50.2 63.5 60.0 71.8 57.5 47.7 76.3 42.7 0.0 0.0 0.0 58.8 0.0 12.2 1.7 15.6 4.0 0.0 0.0 0.1 0.6 0.0 4.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 6.9 5.8 0.4 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 12.2 0.0 0.4 4.6 0.0 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.2 0.0 0.0 0.0 0.4 0.1 0.3 31.0 3.8 0.0 0.3 0.0 0.0 2.4 GJB7 "bA136M9.1, CX25" ENSG00000164411 "Gap junction protein beta 7" Q6PEY0 6 87282980-87329278 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 7.0;pituitary gland: 5.5;placenta: 2.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 10.4;Endometrial ciliated cells: 12.8;Ionocytes: 22.4;Respiratory ciliated cells: 18.4;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.5;HDLM-2: 7.6;MCF7: 4.1;OE19: 4.8;RT4: 3.6;SuSa: 2.4" "Not detected" "Not detected" HPA014392 Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA014392: " "unprognostic (8.30e-2)" "unprognostic (2.45e-1)" "unprognostic (3.06e-1)" "unprognostic (4.20e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-3)" "unprognostic (2.61e-1)" "unprognostic (5.13e-3)" "unprognostic (6.69e-3)" "unprognostic (1.59e-1)" "unprognostic (3.82e-2)" "unprognostic (4.15e-2)" "unprognostic (3.24e-1)" "unprognostic (5.64e-2)" "unprognostic (2.09e-2)" "unprognostic (3.10e-2)" 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.0 0.1 5.5 2.6 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 1.5 0.0 0.1 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 4.1 0.0 0.1 1.2 4.8 0.0 0.1 0.0 0.0 0.0 3.6 0.1 0.0 0.8 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.0 0.6 0.1 0.1 0.4 0.1 0.5 0.0 0.1 0.2 0.2 0.0 0.0 0.7 0.1 0.0 0.0 1.3 0.0 2.5 0.6 0.3 0.2 0.0 0.5 0.0 0.0 10.4 0.5 0.1 0.0 0.2 1.1 12.8 0.8 0.3 0.0 0.0 0.7 0.2 4.4 0.6 0.0 3.0 0.0 0.1 0.4 0.0 0.5 0.0 1.1 0.0 22.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 18.4 0.6 0.0 1.7 0.3 0.3 0.3 0.0 0.0 7.3 0.5 0.2 0.3 0.2 GJC1 "CX45, GJA7" ENSG00000182963 "Gap junction protein gamma 1" P36383 17 44798448-44830816 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 40.0" "Group enriched" "Detected in many" 4 "Sertoli cells: 157.8;Smooth muscle cells: 101.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 2.0" "Lineage enriched" "Detected in single" 4 "granulocytes: 2.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071788 Uncertain "Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 48: Smooth muscle cells - ECM organization" Nucleoli "Cell Junctions, Cytosol" "HPA071788: " "unprognostic (1.84e-2)" "unprognostic (2.04e-1)" "unprognostic (2.13e-2)" "unprognostic (1.35e-1)" "unprognostic (1.75e-1)" "unprognostic (2.22e-1)" "unprognostic (7.02e-2)" "unprognostic (4.01e-1)" "unprognostic (1.60e-2)" "unprognostic (1.11e-1)" "unprognostic (3.02e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.55e-8)" "unprognostic (5.18e-2)" "unprognostic (2.20e-1)" "unprognostic (8.52e-2)" "prognostic unfavorable (7.83e-4)" 9.5 0.7 3.1 3.6 2.8 0.8 5.2 10.1 3.8 9.2 5.5 28.6 1.6 24.7 2.9 2.7 5.3 5.4 11.8 2.3 1.4 2.2 0.7 7.2 2.7 2.1 2.9 2.2 1.4 3.4 0.6 40.0 2.6 8.9 2.9 1.0 1.1 18.6 4.6 2.0 5.3 32.7 1.3 0.7 7.6 8.8 4.0 1.6 6.7 5.9 2.0 11.4 6.1 3.0 44.5 21.9 62.0 18.9 8.3 10.6 20.5 50.3 36.6 50.0 52.6 12.4 24.7 0.5 2.3 46.4 69.9 10.1 29.2 13.7 70.8 0.5 19.8 0.4 12.1 1.6 3.8 0.3 1.7 8.8 1.6 37.0 11.8 20.4 17.1 9.6 1.8 0.5 31.4 0.4 6.7 4.3 29.5 0.1 16.2 39.5 73.8 0.3 11.4 16.8 10.2 21.5 4.6 0.5 16.2 41.3 10.9 8.0 12.3 43.8 39.3 22.2 38.9 0.4 11.3 32.5 15.9 0.3 40.7 2.0 0.2 0.2 0.2 0.1 0.2 0.2 0.1 0.1 0.0 0.2 0.2 0.2 1.0 0.5 0.1 0.2 0.1 0.1 3.1 2.8 10.1 3.8 2.3 1.4 2.1 2.9 2.6 1.3 4.0 3.0 11.7 0.0 0.0 0.7 0.2 2.0 1.7 0.5 0.0 3.4 0.6 1.4 25.1 0.0 0.2 1.8 2.1 0.5 0.4 0.1 0.0 1.5 1.5 1.4 14.9 19.5 0.0 0.0 8.1 0.0 2.6 6.3 0.0 3.0 0.0 9.4 4.2 0.3 1.5 13.5 1.4 0.0 0.0 0.3 4.2 0.3 1.5 1.2 3.6 1.0 0.6 0.2 0.0 0.0 0.3 0.6 0.0 2.2 0.0 1.4 0.0 0.3 0.2 0.9 157.8 4.8 101.1 15.6 28.4 0.6 3.0 0.5 0.8 7.8 0.1 1.3 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLO1 GLOD1 ENSG00000124767 "Glyoxalase I" Q04760 6 38675925-38703145 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "HMC-1: 2571.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB040541, CAB040542, HPA059791" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 1500000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB040541: , CAB040542: , HPA059791: AB_2684126" "unprognostic (4.33e-2)" "unprognostic (1.09e-1)" "unprognostic (4.37e-2)" "unprognostic (1.08e-2)" "unprognostic (3.96e-3)" "unprognostic (2.51e-1)" "prognostic unfavorable (5.21e-4)" "unprognostic (5.09e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (8.71e-2)" "unprognostic (1.20e-2)" "unprognostic (9.29e-2)" "unprognostic (1.83e-1)" "unprognostic (2.54e-1)" "unprognostic (6.21e-2)" 55.4 62.3 69.4 38.9 74.1 31.6 74.2 74.6 83.4 55.9 77.2 51.8 116.3 57.8 110.9 60.0 72.3 41.4 88.9 72.6 76.2 87.2 157.7 66.6 48.4 73.7 72.8 82.8 42.1 106.1 23.2 64.1 75.1 171.4 52.3 100.3 43.2 62.1 154.2 66.6 67.7 61.8 77.9 48.2 48.5 27.9 72.9 50.0 54.8 128.8 60.3 52.4 51.6 77.1 201.6 92.0 257.4 256.7 119.2 213.9 227.0 171.1 161.4 235.4 243.0 224.4 75.3 222.5 132.2 137.5 280.1 129.5 222.5 221.1 295.8 203.8 343.0 329.4 105.7 211.3 178.5 126.7 2571.5 183.9 133.5 223.7 159.0 153.2 258.5 154.9 264.7 143.6 223.3 170.6 199.5 160.5 185.5 179.2 176.7 171.0 311.1 145.8 217.8 149.9 199.3 201.3 120.6 165.4 329.8 175.9 192.4 628.3 107.6 182.0 167.1 159.8 275.9 112.7 227.0 608.6 66.1 322.7 299.6 23.7 20.7 15.3 35.5 33.4 48.0 51.9 35.3 36.7 39.0 51.4 32.7 34.9 2.7 23.5 26.9 60.4 34.1 33.3 69.4 74.1 74.6 83.4 72.6 76.2 73.7 72.8 75.1 77.9 72.9 77.1 69.2 131.4 174.4 26.1 86.3 64.6 112.6 88.2 37.0 56.1 67.7 55.8 133.2 58.6 84.5 90.1 20.9 102.7 68.3 34.1 248.4 132.1 4.5 76.2 58.8 74.3 36.5 83.5 23.9 73.3 323.0 86.0 53.0 67.5 71.4 78.7 161.0 114.0 78.8 69.0 21.9 39.3 99.7 125.7 72.8 6.5 83.9 70.0 104.9 17.8 92.6 190.3 49.4 25.1 24.8 77.3 36.0 109.9 86.4 178.8 103.2 132.2 80.7 65.5 46.0 62.0 70.9 15.0 16.1 77.2 88.2 73.2 62.4 123.7 63.4 130.2 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 777.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 723.9;Extravillous trophoblasts: 751.2;Proximal enterocytes: 968.3;Proximal tubular cells: 1165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 569.0;RPTEC TERT1: 462.1;U-87 MG: 441.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 6300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB008634: AB_1616672, CAB069419: AB_1616670, HPA046431: AB_2679663" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.62e-3)" "unprognostic (9.31e-3)" "unprognostic (1.99e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (2.61e-1)" 82.1 101.4 32.5 80.0 34.9 173.7 37.2 46.3 52.4 28.2 29.0 57.2 194.7 12.7 10.1 13.6 17.2 50.8 102.7 47.3 37.1 247.4 143.6 71.9 61.5 52.0 42.1 10.9 10.9 82.4 23.7 102.0 39.8 28.5 47.4 6.9 59.2 25.6 777.4 38.3 170.3 25.7 34.3 64.9 40.2 4.9 43.6 75.6 18.9 55.9 80.4 53.1 20.9 37.9 22.2 97.1 8.4 18.0 211.3 310.4 1.6 326.5 569.0 35.9 62.9 31.2 10.2 86.2 45.7 99.0 83.0 9.7 12.9 156.4 100.5 75.7 24.1 62.8 63.5 248.1 386.6 67.2 182.8 184.4 23.2 219.7 21.3 81.1 75.3 179.3 8.2 51.3 262.3 7.9 121.4 133.0 22.2 3.3 111.6 186.1 66.8 107.9 462.1 16.8 23.6 12.5 85.3 47.8 39.4 22.0 13.0 66.0 78.0 91.9 101.9 74.6 14.4 37.1 202.0 70.4 441.3 170.6 19.7 48.9 727.2 901.6 222.9 483.8 313.6 142.9 205.0 166.7 459.8 107.8 201.4 186.1 783.8 113.4 411.2 166.6 457.7 781.7 32.5 34.9 46.3 52.4 47.3 37.1 52.0 42.1 39.8 34.3 43.6 37.9 77.5 22.4 28.4 3.6 74.1 17.2 62.9 330.5 8.6 2.2 57.9 31.5 154.9 65.8 183.6 93.8 0.0 47.4 130.0 173.8 723.9 60.4 0.3 83.4 49.0 47.1 31.7 63.1 8.7 96.0 751.2 63.1 35.7 118.0 31.6 3.5 46.4 206.9 271.5 0.0 8.0 89.9 65.1 304.9 276.1 2.3 19.0 232.3 69.4 12.2 340.0 7.8 302.8 2.0 2.4 113.5 291.3 13.9 200.2 89.5 968.3 1165.9 124.1 3.9 19.7 22.1 67.0 0.6 1.6 4.1 20.6 285.3 97.7 11.7 85.4 214.6 GLUL GLNS ENSG00000135821 "Glutamate-ammonia ligase" P15104 1 182378098-182392206 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Angiogenesis "Ligase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1443.6" "Group enriched" "Detected in all" 4 "Late spermatids: 8544.2;Muller glia cells: 6247.0" "Cancer enhanced" "Detected in all" "liver cancer: 365.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 656.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 656.8" "Cell line enhanced" "Detected in many" "ASC diff: 1150.8;ASC TERT1: 807.6;HSkMC: 702.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007316, HPA007571, CAB008636" Approved Supported "Plasma membrane,Mitochondria,Cytosol" NA NA 150000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "CAB008636: AB_1616669, HPA007316: AB_888438, HPA007571: AB_1078980" "prognostic favorable (4.81e-4)" "unprognostic (1.52e-3)" "unprognostic (3.89e-1)" "unprognostic (3.32e-1)" "unprognostic (1.25e-1)" "unprognostic (9.52e-2)" "unprognostic (7.58e-2)" "unprognostic (1.03e-1)" "unprognostic (1.26e-1)" "unprognostic (8.92e-2)" "unprognostic (1.32e-1)" "unprognostic (1.17e-1)" "unprognostic (1.38e-2)" "unprognostic (4.17e-2)" "unprognostic (2.06e-1)" "unprognostic (5.55e-2)" "unprognostic (4.53e-3)" 753.5 76.0 694.3 156.9 746.5 232.9 573.5 717.5 1237.1 161.4 583.2 157.8 24.4 116.7 115.7 218.7 224.3 105.4 129.7 676.6 764.7 65.3 280.7 221.7 75.2 891.0 783.7 303.0 204.7 32.3 70.5 176.6 767.0 103.4 92.5 891.1 233.5 96.0 1443.6 231.4 148.2 124.1 725.0 216.4 648.2 87.1 811.4 97.0 257.4 472.0 103.2 185.5 292.0 810.4 26.4 10.8 117.2 0.2 1150.8 807.6 86.0 44.1 141.7 25.9 23.4 64.1 26.7 22.4 46.3 85.5 23.8 59.3 51.8 309.4 21.5 61.2 143.3 296.5 47.6 124.8 61.1 132.6 227.2 702.1 363.3 32.9 384.6 39.1 52.8 71.7 254.3 13.3 92.6 15.0 208.2 126.5 87.3 36.8 55.0 74.3 31.3 38.6 45.8 114.0 79.7 52.5 12.4 157.3 17.4 93.3 153.1 165.9 39.7 0.9 1.9 0.8 10.1 4.8 3.4 0.4 22.3 73.9 5.0 396.5 153.4 409.4 42.3 145.8 17.6 11.5 29.9 35.5 80.0 17.8 15.3 25.3 656.8 27.2 130.5 43.7 13.0 172.0 694.3 746.5 717.5 1237.1 676.6 764.7 891.0 783.7 767.0 725.0 811.4 810.4 127.8 125.0 173.8 599.4 37.6 134.7 533.8 1190.7 260.0 105.6 166.6 99.1 216.2 171.6 855.3 82.8 52.1 161.7 113.4 118.3 74.3 124.2 1491.3 140.2 150.0 191.5 325.9 319.7 3.4 116.6 65.9 404.4 388.4 124.6 786.3 88.0 152.8 597.1 798.0 43.7 22.0 256.7 451.6 907.2 614.1 8544.2 487.4 687.4 136.9 74.9 112.7 6247.0 42.2 38.2 330.0 108.1 105.3 375.0 38.7 421.0 10.3 46.6 569.9 176.0 92.1 481.5 218.5 48.2 63.6 186.5 128.3 235.3 108.6 53.3 173.3 1420.5 GMIP ARHGAP46 ENSG00000089639 "GEM interacting protein" Q9P107 19 19629476-19643657 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 50.9;lymphoid tissue: 54.3" "Cell type enhanced" "Detected in many" "B-cells: 26.6;Gastric mucus-secreting cells: 24.5;Hofbauer cells: 22.7;Kupffer cells: 33.3;Macrophages: 26.7;monocytes: 27.6;T-cells: 25.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 92.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042484, HPA045481" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042484: AB_2678018, HPA045481: AB_2679343" "unprognostic (7.54e-2)" "unprognostic (5.35e-3)" "unprognostic (3.10e-3)" "unprognostic (4.54e-3)" "unprognostic (1.44e-1)" "unprognostic (1.24e-3)" "unprognostic (1.23e-2)" "unprognostic (4.29e-2)" "unprognostic (1.12e-1)" "unprognostic (2.30e-1)" "unprognostic (6.85e-2)" "unprognostic (6.75e-3)" "prognostic unfavorable (3.97e-5)" "prognostic favorable (3.03e-4)" "unprognostic (4.92e-2)" "unprognostic (2.54e-1)" "prognostic favorable (5.15e-4)" 7.5 3.3 2.9 32.0 2.4 50.9 5.4 2.5 6.1 3.7 2.5 9.6 10.4 3.3 1.4 8.6 5.4 6.0 2.9 3.8 4.0 4.3 4.7 16.9 29.4 6.5 4.4 2.6 6.0 8.9 3.6 4.6 5.7 5.4 6.5 0.4 6.9 2.8 1.1 6.9 22.6 4.3 4.5 54.3 16.7 2.9 6.6 19.1 8.5 1.9 22.9 8.3 5.3 7.4 9.9 4.5 5.9 6.5 6.4 3.3 23.5 6.1 5.2 3.6 3.4 3.6 13.0 24.1 12.1 4.3 4.7 11.5 3.9 6.7 2.3 8.3 6.1 7.6 7.1 4.0 1.9 21.7 92.0 4.2 4.5 3.9 2.0 4.2 8.2 21.1 5.3 8.5 3.9 14.6 13.7 35.8 3.5 12.7 8.1 23.3 2.6 14.0 6.9 23.3 5.1 15.2 8.4 8.7 3.7 4.5 8.0 30.7 15.0 6.6 3.8 7.6 4.6 4.3 1.9 19.8 4.2 28.0 4.6 7.0 19.5 51.9 13.2 23.7 12.3 12.6 8.4 11.9 15.1 12.8 8.9 9.7 71.8 9.7 33.1 13.5 10.0 12.5 2.9 2.4 2.5 6.1 3.8 4.0 6.5 4.4 5.7 4.5 6.6 7.4 1.7 0.0 10.2 0.3 26.6 1.1 1.7 2.5 1.2 0.0 1.9 1.3 0.9 2.8 3.1 0.0 0.0 0.6 14.9 21.2 0.0 4.1 0.1 1.4 0.9 1.8 0.0 1.3 2.1 4.7 5.3 0.9 24.5 4.0 7.0 3.5 2.5 1.6 22.7 0.0 2.1 6.6 0.0 33.3 6.6 0.4 0.6 26.7 1.8 6.5 27.6 0.4 20.6 0.5 0.2 12.9 20.2 0.7 13.9 2.0 9.3 0.7 1.5 0.1 0.0 0.4 1.6 0.6 1.3 3.5 1.1 0.8 25.8 0.9 6.0 4.1 GNAI2 "GIP, GNAI2B" ENSG00000114353 "G protein subunit alpha i2" P04899 3 50226292-50259362 "Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 656.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007704 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 4000000 "Cluster 52: Eosinophils - Transcription" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 7: Non-specific - Mitochondria" Cytosol "Nucleoplasm, Plasma membrane" "HPA007704: AB_1849230" "prognostic favorable (1.03e-4)" "unprognostic (3.89e-1)" "unprognostic (3.35e-2)" "unprognostic (8.40e-3)" "unprognostic (2.58e-1)" "unprognostic (2.32e-2)" "unprognostic (2.59e-2)" "unprognostic (3.23e-1)" "unprognostic (1.08e-3)" "unprognostic (6.01e-2)" "unprognostic (7.00e-3)" "unprognostic (1.12e-1)" "unprognostic (6.24e-3)" "unprognostic (1.44e-1)" "unprognostic (4.30e-2)" "unprognostic (4.33e-2)" "unprognostic (1.38e-1)" 210.2 100.3 155.2 217.9 167.3 367.1 152.8 166.3 181.6 146.0 120.2 142.1 69.9 141.7 66.9 124.4 136.9 152.5 157.1 144.3 184.6 79.4 126.5 214.5 251.3 199.8 170.2 147.7 64.1 66.9 99.2 241.8 194.8 103.6 64.3 35.6 71.9 156.9 69.3 87.0 103.0 154.0 173.6 262.1 73.6 69.6 173.3 160.3 101.3 89.4 170.4 169.7 108.4 193.2 128.2 63.0 186.3 197.6 220.7 277.5 35.5 271.1 399.6 354.9 361.1 70.4 173.2 149.1 119.2 567.0 193.4 100.1 132.8 350.3 222.8 331.2 50.9 364.8 158.0 110.2 219.8 329.2 479.8 270.3 152.9 319.1 129.8 289.6 837.8 124.1 26.1 307.1 357.5 155.7 313.6 433.0 109.7 59.0 302.4 185.0 89.8 219.7 232.6 130.9 48.4 86.1 189.5 57.1 124.4 150.4 94.3 346.1 792.3 330.9 187.5 309.2 274.7 199.4 278.3 127.0 373.6 466.9 398.1 16.6 59.3 113.7 33.7 80.9 20.2 28.8 26.8 34.3 57.3 26.1 20.2 25.8 145.2 23.5 74.5 47.2 34.0 27.3 155.2 167.3 166.3 181.6 144.3 184.6 199.8 170.2 194.8 173.6 173.3 193.2 656.8 41.7 32.1 25.1 119.5 56.7 59.7 32.3 45.5 29.0 61.6 83.8 22.9 55.8 26.6 44.1 14.6 79.5 311.4 11.7 5.9 124.3 203.3 57.8 115.7 340.3 92.2 52.1 12.4 60.5 84.4 101.9 21.9 71.8 89.9 150.0 221.3 79.7 336.0 6.7 14.8 24.6 18.3 342.7 291.7 302.0 90.7 386.1 83.6 58.1 356.6 292.6 151.4 26.7 45.4 160.3 40.9 95.5 104.8 46.1 30.3 24.5 24.4 21.9 52.6 85.3 163.1 16.6 22.6 37.6 62.9 116.4 164.9 156.3 20.5 70.1 GNAQ "G-ALPHA-q, GAQ" ENSG00000156052 "G protein subunit alpha q" P50148 9 77716097-78031811 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" Transducer "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 556.6;Excitatory neurons: 405.6;Microglial cells: 394.4;Oligodendrocyte precursor cells: 338.3;Oligodendrocytes: 495.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 27.0" "Lineage enriched" "Detected in many" 6 "granulocytes: 27.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010036, HPA048886" Uncertain Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA 800000 "Cluster 38: Basophils - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB010036: AB_631536, HPA048886: AB_2680544" "unprognostic (2.10e-1)" "unprognostic (8.53e-2)" "unprognostic (1.45e-1)" "unprognostic (4.37e-2)" "unprognostic (1.87e-1)" "unprognostic (6.83e-3)" "unprognostic (1.05e-1)" "unprognostic (3.84e-2)" "unprognostic (2.46e-1)" "unprognostic (2.16e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.11e-7)" "unprognostic (1.90e-1)" "unprognostic (3.13e-1)" "unprognostic (1.05e-1)" "unprognostic (2.01e-1)" 23.5 21.3 37.2 18.8 42.2 43.8 20.1 35.8 51.3 21.1 19.3 30.3 14.5 23.7 18.7 23.2 16.9 20.1 8.6 51.0 38.5 20.9 22.0 31.1 9.9 40.5 42.7 22.4 14.6 16.3 12.5 21.7 39.9 21.2 27.2 10.4 16.8 25.7 10.5 8.9 16.8 27.4 42.4 11.3 27.9 11.5 45.5 19.7 23.1 11.8 9.1 23.5 13.8 48.5 30.6 34.1 29.8 32.0 34.9 35.5 42.8 40.7 29.7 16.6 20.6 10.5 24.1 0.1 32.0 35.5 24.5 48.5 22.5 23.4 20.6 1.1 12.5 83.0 29.0 21.4 31.4 51.8 30.0 24.3 28.0 33.9 32.5 34.3 42.7 70.3 14.8 0.2 29.5 38.5 58.8 31.0 24.0 46.5 4.7 22.0 36.5 0.3 37.8 64.5 33.1 49.6 29.3 23.3 30.5 27.5 22.2 18.3 55.0 29.2 1.9 41.9 24.0 0.2 0.1 0.3 20.3 28.9 32.0 27.0 2.5 5.7 0.8 2.2 1.7 0.9 2.0 1.1 2.8 0.9 2.1 1.7 8.9 3.6 4.5 3.2 2.2 1.5 37.2 42.2 35.8 51.3 51.0 38.5 40.5 42.7 39.9 42.4 45.5 48.5 117.7 176.3 97.5 556.6 4.8 47.3 38.4 42.7 39.3 34.0 75.6 54.5 6.0 58.6 48.3 77.3 16.7 47.4 33.4 137.0 7.9 36.2 18.9 57.5 64.2 107.3 92.3 58.0 405.6 39.7 53.2 51.7 70.8 76.0 50.7 40.2 98.6 64.0 53.7 82.4 242.0 92.5 30.5 139.5 173.9 11.1 39.4 128.8 48.0 394.4 114.6 40.5 8.2 338.3 495.2 54.2 60.7 52.3 6.2 70.5 52.9 45.4 67.0 5.0 26.3 62.3 40.8 5.6 13.2 46.3 21.6 29.0 25.0 45.2 75.4 70.1 GNAS "GNAS1, GNASXL, GPSA, NESP, NESP55, SCG6, SgVI" ENSG00000087460 "GNAS complex locus" "O95467, P63092, P84996, Q5JWF2" 20 58839718-58911192 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transducer "Cancer-related genes, Cushing syndrome, Disease variant, Dwarfism, Obesity, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Horizontal cells: 1886.1;Late spermatids: 1756.9;Skeletal myocytes: 1998.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010337, HPA018122, HPA027478, HPA028386" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Plasma membrane, Cytosol" "CAB010337: AB_631538, HPA018122: AB_1849236, HPA027478: AB_10599284, HPA028386: AB_10601983" "unprognostic (7.48e-2)" "unprognostic (1.41e-1)" "unprognostic (3.90e-2)" "unprognostic (4.77e-2)" "unprognostic (8.37e-3)" "unprognostic (2.82e-2)" "unprognostic (4.53e-3)" "unprognostic (8.01e-2)" "unprognostic (4.29e-2)" "prognostic favorable (8.76e-4)" "unprognostic (2.07e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (3.49e-4)" "unprognostic (5.24e-3)" "unprognostic (1.61e-1)" "unprognostic (8.25e-2)" "unprognostic (1.36e-1)" 784.8 1215.3 1564.4 512.6 1524.7 887.4 578.9 1413.1 1768.3 828.5 1373.3 657.1 492.4 611.4 1253.8 883.1 742.9 672.7 1990.6 1557.3 2716.9 625.0 651.1 640.3 769.2 1710.5 1949.4 766.5 1917.7 1799.4 1153.6 884.6 1963.4 577.3 607.3 731.2 2943.9 594.4 2400.4 526.8 527.3 782.4 1598.4 606.6 587.1 357.9 1882.0 854.4 3432.2 2813.1 800.0 687.1 239.3 1483.9 215.6 897.3 1501.9 663.3 2691.8 1822.3 1200.1 1219.1 1635.0 1937.3 1201.8 2480.5 1446.7 911.9 1670.3 2314.3 1305.6 976.1 1499.0 2195.3 1540.9 401.4 784.6 984.9 1651.7 2232.7 1420.7 641.6 483.0 1566.4 1113.6 875.1 1399.1 1561.0 1669.7 1100.6 692.0 1294.6 1319.1 4131.0 1759.5 1452.8 487.9 214.0 894.4 1436.7 1287.3 1589.4 2165.5 1315.8 1818.3 3853.2 2157.6 2117.1 1354.2 1921.8 1570.0 1581.7 1343.3 2210.2 1477.0 688.5 1452.3 1314.0 993.3 1583.2 900.0 473.7 1107.1 217.9 96.7 114.2 68.9 127.3 80.0 103.2 73.4 74.8 129.2 93.6 65.8 82.6 103.4 95.6 150.3 174.9 92.7 100.9 1564.4 1524.7 1413.1 1768.3 1557.3 2716.9 1710.5 1949.4 1963.4 1598.4 1882.0 1483.9 982.6 221.2 258.8 192.0 310.8 130.4 182.0 130.0 205.5 397.8 465.6 684.4 1025.3 237.4 212.2 261.1 56.3 832.6 390.8 357.3 444.1 233.9 734.9 487.7 515.7 518.3 463.1 252.1 232.5 228.9 342.0 380.9 196.3 685.0 138.6 542.3 380.1 256.4 379.1 1886.1 439.7 327.2 181.0 380.4 405.7 1756.9 265.3 437.1 222.3 236.1 204.0 1367.2 137.0 194.5 166.6 339.9 300.0 197.1 309.7 268.1 273.7 153.6 218.0 222.0 210.4 1998.0 560.4 226.0 73.6 240.5 117.8 1211.7 301.8 860.9 304.4 316.5 GNB1 ENSG00000078369 "G protein subunit beta 1" P62873 1 1785285-1891117 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "retina: 2629.0" "Cell type enriched" "Detected in all" 5 "Rod photoreceptor cells: 1373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040736 Supported Approved "Golgi apparatus,Plasma membrane" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (9.49e-2)" "unprognostic (4.91e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (9.07e-3)" "prognostic unfavorable (3.61e-6)" "unprognostic (1.99e-2)" "unprognostic (3.60e-1)" "unprognostic (7.27e-2)" "unprognostic (8.47e-3)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (1.08e-1)" "unprognostic (4.62e-2)" "unprognostic (1.14e-1)" "unprognostic (7.90e-2)" 178.1 123.8 167.9 179.9 212.3 147.6 119.7 147.8 234.4 124.3 87.1 165.7 173.7 127.1 90.8 126.7 114.4 110.9 119.6 228.3 172.0 125.1 103.3 146.7 160.0 159.5 153.2 130.2 105.9 148.2 106.8 141.1 169.5 118.3 123.1 2629.0 120.6 118.9 66.8 111.8 208.2 156.1 131.6 142.6 129.7 99.0 168.9 167.3 113.6 97.1 145.6 152.6 102.7 203.9 373.2 344.2 400.2 280.4 222.4 242.4 154.4 515.4 339.9 456.2 355.2 282.8 361.8 385.5 369.3 522.5 258.6 192.0 405.5 373.5 411.4 595.9 199.2 375.0 308.2 325.6 279.1 227.7 394.4 216.4 256.6 437.2 402.9 306.1 376.8 298.8 236.8 337.8 440.0 230.3 501.9 177.4 230.8 190.0 275.0 482.9 308.7 306.4 310.8 227.5 489.9 556.5 477.1 306.6 420.5 272.8 214.8 305.9 579.4 399.3 267.5 314.8 379.1 227.1 432.8 888.7 341.4 470.1 230.5 11.4 13.3 21.9 9.9 16.4 9.1 9.0 9.9 11.2 13.3 9.6 6.7 7.2 22.1 12.8 17.5 22.7 12.5 8.2 167.9 212.3 147.8 234.4 228.3 172.0 159.5 153.2 169.5 131.6 168.9 203.9 172.0 70.5 42.6 57.5 67.9 86.3 51.6 47.4 33.0 149.8 65.3 57.8 60.6 52.9 42.4 75.4 175.2 44.2 124.4 140.9 46.9 88.0 29.1 93.3 112.9 131.6 122.9 40.3 102.4 100.5 99.4 77.8 52.0 121.6 53.8 101.9 95.3 60.3 100.8 180.0 101.9 95.5 40.7 152.7 114.6 33.8 76.1 128.0 53.4 115.2 119.5 250.3 73.2 70.9 110.1 175.4 91.0 88.0 75.3 100.5 167.6 67.4 41.1 1373.7 78.9 71.0 105.9 68.8 67.1 51.6 101.7 36.4 74.5 83.7 83.0 94.1 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNB3 ENSG00000111664 "G protein subunit beta 3" P16520 12 6839954-6847393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "retina: 426.5" "Group enriched" "Detected in many" 7 "Bipolar cells: 471.3;Cone photoreceptor cells: 932.0;Rod photoreceptor cells: 462.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 14.1;NTERA-2: 17.0;U-698: 40.9" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.1" HPA040736 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (3.86e-2)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (2.53e-2)" "unprognostic (5.74e-3)" "unprognostic (5.98e-2)" "unprognostic (4.43e-3)" "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.25e-5)" "unprognostic (3.21e-2)" "unprognostic (4.77e-11)" "unprognostic (2.43e-1)" "unprognostic (6.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-2)" 0.9 1.4 6.3 1.6 6.0 1.0 0.6 6.7 9.5 2.3 6.7 1.4 1.7 2.2 0.7 0.4 1.6 1.1 4.4 5.9 6.6 2.0 0.2 0.7 1.6 5.7 5.3 2.8 0.7 1.5 36.2 0.4 5.6 2.1 0.6 426.5 2.1 1.4 1.3 0.7 1.5 3.2 5.2 0.9 1.0 0.6 5.7 0.3 1.6 0.3 1.6 1.6 1.1 6.4 0.4 1.2 9.4 3.1 1.3 2.0 0.9 4.8 0.8 2.5 2.1 1.9 0.5 14.1 0.1 5.1 0.1 0.5 9.2 0.3 2.3 1.2 2.1 3.4 6.8 1.5 0.9 1.1 2.3 2.4 0.5 2.4 2.7 9.6 2.5 1.8 1.5 1.3 1.2 0.7 0.7 0.8 17.0 0.1 0.5 0.7 2.8 0.9 0.5 0.4 1.1 2.2 0.4 0.1 1.0 2.5 0.1 0.6 4.0 3.2 3.8 4.8 6.7 1.4 1.0 40.9 1.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 6.0 6.7 9.5 5.9 6.6 5.7 5.3 5.6 5.2 5.7 6.4 0.3 0.0 0.0 5.2 1.3 0.4 0.4 0.2 1.2 471.3 0.8 1.3 6.1 0.0 0.1 0.0 932.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 3.3 0.0 1.3 12.3 0.0 0.0 2.3 2.0 0.1 0.0 0.1 1.1 0.0 0.1 74.0 12.4 0.0 4.1 0.3 0.4 0.0 3.7 0.1 1.8 3.7 0.1 86.7 0.0 6.0 1.2 0.1 0.0 3.4 3.2 0.8 0.0 0.1 0.6 462.8 0.0 0.3 1.4 0.1 0.5 0.0 0.0 0.0 0.4 0.2 0.1 0.2 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 14.3;Excitatory neurons: 9.9;Inhibitory neurons: 10.2;Late spermatids: 8.7;Macrophages: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 9.4;K-562: 4.1;U-2 OS: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" 0.1 0.0 0.1 0.0 0.1 0.9 0.2 0.7 0.5 0.5 0.0 0.2 0.0 0.2 0.0 1.4 0.4 0.0 0.7 0.1 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.4 0.1 0.1 1.2 0.1 0.0 0.0 0.9 0.2 2.7 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 9.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.1 0.1 0.7 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.3 0.3 0.0 2.0 0.3 0.4 0.7 1.5 0.3 0.0 6.2 0.1 0.4 0.7 0.0 0.1 14.3 1.4 0.4 1.2 0.0 0.0 9.9 0.4 0.3 0.6 0.0 2.2 1.3 0.8 3.3 0.2 0.1 3.3 10.2 0.0 0.0 0.8 0.2 8.7 0.3 10.3 0.0 1.0 0.3 0.4 2.1 1.5 1.5 0.2 0.1 0.0 0.0 0.4 0.1 0.0 1.9 2.6 0.0 0.4 0.2 1.4 1.2 0.0 0.1 0.5 0.4 0.0 0.3 0.7 GP9 "CD42a, GPIX" ENSG00000169704 "Glycoprotein IX platelet" P14770 3 129060779-129062406 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Blood coagulation, Cell adhesion, Hemostasis" "Bernard Soulier syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 5.1;lung: 3.2;lymphoid tissue: 8.9" "Cell type enriched" "Detected in some" 8 "Macrophages: 151.9" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "basophil: 29.5;neutrophil: 13.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 29.5" "Cell line enriched" "Detected in some" 14 "HEL: 85.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA063182 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2600000 "Cluster 34: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" Nucleoplasm "HPA063182: AB_2684956" "unprognostic (1.70e-1)" "unprognostic (3.97e-1)" "unprognostic (1.10e-1)" "unprognostic (3.80e-2)" "unprognostic (2.50e-2)" "unprognostic (3.24e-1)" "unprognostic (2.53e-2)" "unprognostic (8.47e-2)" "unprognostic (8.70e-2)" 0.1 0.0 0.0 0.0 0.0 5.1 0.1 0.0 0.3 0.1 0.6 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.9 0.1 1.8 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 85.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.5 1.2 0.2 0.2 0.7 0.3 0.0 0.0 0.3 0.6 0.1 0.1 0.0 13.9 0.0 0.2 3.0 0.0 51.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.0 14.4 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 2.9 0.1 1.7 0.0 0.0 0.6 0.0 1.3 0.0 18.3 0.0 151.9 0.0 0.0 4.1 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.4 0.7 0.3 0.0 GPATCH1 "ECGP, FLJ10206, FLJ38686, GPATC1" ENSG00000076650 "G-patch domain containing 1" Q9BRR8 19 33080899-33130542 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043430, HPA043604, HPA074327" Approved Approved "Golgi apparatus,Plasma membrane,Cell Junctions" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cell Junctions" "HPA043430: AB_10960493, HPA043604: AB_10960499, HPA074327: " "unprognostic (2.38e-2)" "unprognostic (1.71e-2)" "unprognostic (9.95e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.41e-1)" "unprognostic (1.28e-2)" "unprognostic (4.60e-3)" "unprognostic (3.54e-2)" "unprognostic (5.17e-2)" "unprognostic (3.56e-2)" "unprognostic (6.53e-2)" "unprognostic (5.37e-3)" "unprognostic (8.10e-2)" "unprognostic (4.57e-2)" "unprognostic (1.25e-1)" "unprognostic (1.45e-2)" "unprognostic (6.88e-3)" 3.5 3.1 3.0 3.5 3.2 3.7 4.4 5.1 4.0 4.0 2.0 4.8 5.4 4.5 4.4 4.3 3.9 2.8 3.8 3.1 2.9 4.4 3.4 3.4 4.9 2.8 3.0 7.2 3.8 6.3 2.6 4.2 3.0 4.2 4.5 3.9 4.6 3.4 4.2 5.6 4.6 4.4 2.7 4.3 4.9 4.4 3.3 5.9 4.7 3.2 5.0 3.6 3.6 3.4 8.8 18.2 8.4 9.1 5.5 6.2 7.1 7.8 5.4 11.6 9.7 12.9 7.9 12.3 9.7 6.2 5.5 7.7 10.6 6.4 10.1 21.4 6.6 11.7 6.8 9.8 7.2 20.3 7.6 5.3 7.4 7.9 7.2 5.6 6.6 9.6 12.5 7.7 5.8 11.2 11.8 7.1 5.9 11.5 7.5 11.9 10.6 5.5 5.4 5.4 9.3 6.2 12.3 7.6 4.6 7.2 6.4 14.5 7.5 10.2 7.6 5.6 11.3 6.4 11.1 10.6 6.3 10.3 9.5 23.1 6.4 7.4 6.0 6.6 4.1 6.2 5.6 7.7 6.0 7.0 9.6 6.0 4.7 3.5 3.7 5.3 9.2 5.0 3.0 3.2 5.1 4.0 3.1 2.9 2.8 3.0 3.0 2.7 3.3 3.4 6.5 9.6 7.9 5.9 9.1 6.1 5.0 6.0 10.8 9.7 5.2 4.6 11.8 1.5 9.8 7.3 14.6 10.5 10.7 12.0 15.6 6.8 3.2 5.2 9.4 6.4 4.2 4.2 7.2 4.5 5.2 7.5 10.2 6.8 16.5 10.1 7.9 4.6 4.1 3.3 7.0 7.7 8.2 6.0 5.2 2.1 10.2 5.8 8.8 2.8 5.8 7.1 16.5 5.5 7.0 9.0 8.7 8.2 5.5 3.3 6.8 6.6 10.3 11.9 0.0 8.0 7.3 19.5 14.8 6.5 3.7 5.5 9.1 7.0 6.5 3.4 GPBP1 DKFZp761C169 ENSG00000062194 "GC-rich promoter binding protein 1" Q86WP2 5 57173948-57264679 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 622.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037773 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Cytosol" "Plasma membrane" "HPA037773: AB_10671721" "unprognostic (1.53e-1)" "unprognostic (2.23e-2)" "unprognostic (1.57e-1)" "unprognostic (3.49e-1)" "unprognostic (8.30e-2)" "unprognostic (9.68e-3)" "unprognostic (1.24e-2)" "unprognostic (3.19e-2)" "unprognostic (6.85e-3)" "unprognostic (3.70e-1)" "unprognostic (5.93e-2)" "unprognostic (5.48e-2)" "unprognostic (3.75e-2)" "unprognostic (1.65e-1)" "unprognostic (4.89e-2)" "unprognostic (2.57e-1)" "prognostic favorable (4.15e-5)" 39.2 48.6 67.6 37.8 72.0 66.0 55.7 87.7 87.8 46.5 63.6 38.9 31.2 42.6 48.0 36.9 47.0 36.6 39.8 66.0 67.8 48.0 44.0 43.5 57.8 66.2 68.0 65.1 35.7 50.1 41.7 43.3 66.8 42.1 36.9 83.7 42.6 36.5 59.0 38.2 40.3 32.7 68.5 48.1 37.6 75.2 67.3 69.0 51.5 56.5 53.0 43.9 38.0 85.4 56.4 45.3 83.7 70.1 53.8 51.6 75.9 42.9 72.4 68.6 88.4 73.0 63.2 74.2 48.0 44.0 84.9 37.5 71.9 48.6 86.8 41.7 48.1 61.9 49.6 61.5 62.9 45.2 60.8 43.6 74.8 56.1 78.1 65.8 56.7 59.5 62.3 117.6 56.4 72.3 70.3 78.6 51.2 28.2 31.3 75.4 68.5 72.7 53.7 58.7 72.7 56.0 62.1 53.4 69.6 54.3 104.9 75.8 37.3 25.0 50.2 35.1 62.0 90.0 79.6 81.6 40.7 66.7 46.9 93.8 38.2 76.4 59.6 41.0 76.3 71.5 72.1 72.6 43.7 61.9 78.5 73.8 73.2 79.5 45.5 29.8 84.9 68.8 67.6 72.0 87.7 87.8 66.0 67.8 66.2 68.0 66.8 68.5 67.3 85.4 132.9 60.9 88.3 129.3 272.2 227.5 241.1 102.6 206.1 139.8 146.1 87.9 89.0 65.8 121.9 84.6 148.0 99.0 246.9 149.6 99.7 76.5 249.9 246.6 134.0 123.1 107.7 82.7 106.4 55.9 74.3 143.2 115.2 267.8 142.8 119.0 68.2 47.0 56.2 134.6 96.4 103.3 118.0 70.3 622.0 102.4 133.9 162.8 188.5 112.4 160.7 95.7 178.2 168.9 221.6 70.5 176.3 91.4 261.6 246.5 87.9 72.6 154.6 199.0 52.6 129.7 139.9 379.3 279.6 195.6 237.7 161.7 285.2 107.0 102.0 304.1 GPBP1L1 SP192 ENSG00000159592 "GC-rich promoter binding protein 1 like 1" Q9HC44 1 45627304-45688113 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028593 Approved Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Focal adhesion sites, Cytosol" "HPA028593: AB_10602906" "unprognostic (1.39e-1)" "unprognostic (8.41e-2)" "unprognostic (1.44e-3)" "unprognostic (6.60e-2)" "unprognostic (6.35e-2)" "unprognostic (1.97e-3)" "unprognostic (2.42e-3)" "unprognostic (9.79e-2)" "unprognostic (3.91e-2)" "unprognostic (1.94e-3)" "unprognostic (1.12e-2)" "unprognostic (4.11e-1)" "unprognostic (1.25e-2)" "unprognostic (6.63e-2)" "unprognostic (4.51e-1)" "unprognostic (7.56e-3)" "unprognostic (6.13e-2)" 28.7 26.7 25.2 31.0 29.4 49.3 40.9 27.3 28.0 35.0 26.1 57.3 54.0 35.6 37.6 45.0 36.2 30.3 41.7 23.6 27.1 47.0 66.3 39.2 39.9 27.7 28.3 30.6 39.3 41.7 25.5 34.1 28.2 35.8 61.2 27.4 42.4 36.1 46.2 47.2 56.7 36.3 26.8 36.9 42.6 57.9 27.4 54.7 48.7 54.9 49.5 35.6 36.7 32.8 41.1 24.7 42.1 44.9 48.4 47.1 57.5 31.9 52.2 44.8 56.1 25.2 44.8 56.3 40.5 43.7 46.9 42.0 46.6 47.8 56.3 64.4 33.4 73.7 28.9 39.2 66.7 74.2 65.1 34.6 102.0 35.3 99.4 60.2 57.7 71.0 63.7 48.7 51.6 22.0 66.2 65.8 60.4 54.8 27.7 43.0 55.1 41.9 51.5 40.2 51.9 34.7 52.6 76.6 83.5 81.6 35.1 86.2 49.8 32.0 33.6 35.2 48.9 47.2 46.9 41.3 34.0 60.6 34.5 24.0 21.6 40.3 21.6 27.3 22.9 16.5 20.9 21.1 23.0 14.1 22.6 22.4 22.6 26.6 30.6 13.1 26.4 21.1 25.2 29.4 27.3 28.0 23.6 27.1 27.7 28.3 28.2 26.8 27.4 32.8 43.3 60.9 24.4 54.5 45.1 64.9 41.2 28.3 59.2 23.5 51.3 33.5 46.9 41.5 34.3 60.7 35.5 26.2 47.5 96.8 50.9 33.0 23.4 38.1 32.2 38.6 38.3 62.1 48.5 38.9 33.7 25.4 44.9 47.5 59.6 24.3 37.5 81.3 25.0 37.0 49.0 67.2 32.6 49.9 51.6 17.6 20.5 46.1 23.2 70.3 41.3 18.2 45.3 50.8 93.8 51.2 57.0 21.4 36.6 62.8 75.5 58.7 33.0 32.9 19.7 22.4 42.0 78.9 75.3 71.7 67.8 45.4 47.1 27.7 68.6 78.2 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Alveolar cells type 2: 29.2;Astrocytes: 54.5;Extravillous trophoblasts: 36.2;Granulosa cells: 30.6;Proximal tubular cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 209.7;HAP1: 121.8;NTERA-2: 110.3;RPTEC TERT1: 276.6;SuSa: 242.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 190000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" 9.6 9.8 5.9 4.9 6.4 0.1 5.6 5.0 5.8 12.0 4.6 22.5 10.6 10.8 16.4 7.4 11.2 9.0 7.9 6.3 7.5 20.6 1.8 17.4 2.5 7.2 6.9 12.3 10.8 5.6 16.6 29.0 6.0 8.0 10.9 1.2 13.0 11.4 24.3 3.8 10.8 17.7 6.6 5.7 16.9 7.8 4.9 8.4 5.9 20.0 2.0 10.3 5.2 8.5 0.0 0.0 209.7 8.3 8.9 1.3 26.0 1.6 0.0 0.0 0.0 0.1 0.5 0.3 71.7 1.2 0.0 0.1 121.8 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 37.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 6.0 0.1 0.1 110.3 0.0 3.2 0.6 19.2 0.0 276.6 8.4 0.1 1.5 0.8 0.1 0.1 242.0 3.2 3.2 0.0 21.3 24.8 0.0 13.6 0.0 0.0 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.4 5.0 5.8 6.3 7.5 7.2 6.9 6.0 6.6 4.9 8.5 1.7 51.3 29.2 54.5 0.2 1.5 3.7 14.7 14.2 0.0 2.9 2.0 4.4 5.7 8.7 23.9 0.0 0.5 0.2 2.5 3.9 7.0 0.6 5.9 1.7 1.2 2.4 0.0 4.7 12.7 36.2 14.4 6.6 10.0 0.0 30.6 0.0 0.0 2.5 0.0 1.4 11.1 4.1 0.6 3.9 2.1 2.1 2.0 1.8 14.0 1.1 1.0 0.0 4.5 4.3 16.5 4.3 0.4 0.1 1.4 4.6 30.3 12.8 0.1 0.0 6.3 13.6 2.4 23.6 2.3 0.4 3.1 1.0 1.4 11.3 0.6 GPI "AMF, NLK" ENSG00000105220 "Glucose-6-phosphate isomerase" P06744 19 34359480-34402413 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Gluconeogenesis, Glycolysis" "Cytokine, Growth factor, Isomerase" "Cancer-related genes, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 331.0;Late spermatids: 1127.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018655, HPA024305, CAB040563, HPA052171" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" No No 86000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB018655: AB_2112653, CAB040563: , HPA024305: AB_1849922, HPA052171: AB_2681748" "unprognostic (1.03e-1)" "unprognostic (8.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.38e-2)" "unprognostic (4.52e-2)" "unprognostic (6.45e-3)" "unprognostic (1.95e-2)" "unprognostic (8.52e-3)" "unprognostic (3.18e-1)" "unprognostic (1.45e-1)" "unprognostic (4.93e-2)" "unprognostic (2.75e-1)" "unprognostic (3.24e-3)" "unprognostic (2.62e-2)" "unprognostic (2.43e-1)" "unprognostic (2.60e-3)" "unprognostic (2.88e-2)" 196.9 283.2 83.4 74.5 101.9 222.8 129.0 67.7 130.5 95.0 84.8 162.9 113.7 92.4 27.2 197.8 88.8 87.1 407.2 108.5 73.6 196.8 222.6 91.2 66.4 73.5 58.5 97.0 84.2 166.3 147.2 47.5 69.3 94.4 84.3 156.1 105.1 61.0 416.6 120.1 126.5 78.4 34.0 102.2 122.5 95.9 83.2 50.1 100.8 374.6 76.0 147.9 121.5 95.8 572.9 596.1 58.7 433.3 167.5 121.9 134.1 183.4 132.4 206.3 253.7 314.9 169.6 303.5 311.4 177.9 149.1 343.7 337.7 437.0 259.4 461.0 105.1 382.1 252.3 310.8 108.4 517.6 259.3 173.7 136.6 289.0 132.7 273.3 209.3 230.5 210.3 261.8 140.2 319.2 245.5 133.5 158.0 421.3 174.6 242.7 149.1 649.4 254.1 275.4 304.9 185.8 331.9 634.3 131.7 100.5 144.4 161.7 171.9 80.8 185.5 256.7 312.8 535.5 383.7 318.4 287.4 372.3 170.6 188.8 93.2 331.3 80.4 141.2 99.1 59.9 73.7 93.1 101.0 50.5 61.8 72.8 7.4 58.0 180.3 31.6 83.4 123.4 83.4 101.9 67.7 130.5 108.5 73.6 73.5 58.5 69.3 34.0 83.2 95.8 34.2 28.9 40.0 98.9 43.8 25.9 30.1 104.5 42.7 98.8 34.1 27.2 232.5 42.9 51.4 57.0 75.0 44.5 41.6 76.7 115.4 101.7 331.0 35.9 41.2 38.0 63.7 46.7 121.8 66.9 69.2 47.1 109.1 58.0 23.4 36.1 42.8 89.5 89.6 237.2 127.2 75.8 50.8 52.9 40.5 1127.2 37.0 58.1 35.6 17.8 44.4 32.6 23.7 43.7 87.7 77.6 39.4 30.5 77.1 31.5 111.8 103.0 33.1 68.3 19.7 44.3 65.0 7.8 22.3 139.1 32.8 39.3 64.3 74.8 126.9 37.2 GPR1 ENSG00000183671 "G protein-coupled receptor 1" P46091 2 206175316-206218047 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 12.2" "Group enriched" "Detected in some" 6 "Extravillous trophoblasts: 12.3;Granulosa cells: 42.1" "Cancer enhanced" "Detected in many" "head and neck cancer: 2.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 24.7;HHSteC: 133.9;hTCEpi: 61.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA010525 Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA010525: AB_1078919" "unprognostic (5.32e-2)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (2.25e-2)" "unprognostic (3.27e-5)" "unprognostic (1.36e-1)" "unprognostic (4.00e-3)" "unprognostic (1.49e-2)" "unprognostic (7.89e-2)" "unprognostic (9.94e-2)" "unprognostic (3.42e-3)" "unprognostic (5.65e-2)" "unprognostic (4.29e-4)" "unprognostic (8.48e-4)" "unprognostic (1.21e-1)" "unprognostic (2.68e-2)" "unprognostic (3.06e-3)" 1.5 2.7 0.1 0.2 0.9 0.0 0.7 0.5 0.3 2.6 12.2 0.3 0.1 0.5 0.2 4.5 0.5 1.2 1.6 0.6 0.3 0.4 0.0 0.2 0.8 0.0 0.0 1.3 0.0 0.4 0.2 3.9 0.0 0.2 0.3 0.7 0.9 0.1 0.7 4.8 0.3 1.0 0.0 0.0 0.1 0.9 0.2 0.0 0.3 2.4 0.3 1.0 5.6 0.0 2.2 0.2 1.8 0.0 0.4 7.5 0.6 14.4 24.7 8.8 7.4 0.0 0.0 0.0 0.8 7.3 0.6 0.2 0.7 0.0 2.9 0.0 0.3 0.0 4.2 0.0 133.9 0.0 0.0 5.5 61.8 12.5 20.0 10.2 0.0 0.0 0.0 0.0 17.8 0.0 0.0 0.0 6.9 0.5 1.3 0.0 0.0 0.0 0.0 0.0 0.3 6.1 2.9 0.0 0.0 1.6 0.1 0.0 0.3 10.5 4.8 12.5 1.1 0.0 0.0 0.0 3.8 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.5 0.3 0.6 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.6 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.8 0.0 12.3 4.5 0.0 0.0 0.0 42.1 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.9 1.2 0.0 0.0 0.8 1.0 0.7 0.5 0.0 0.0 0.4 GPR142 PGR2 ENSG00000257008 "G protein-coupled receptor 142" Q7Z601 17 74367407-74372622 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 4 "pancreatic cancer: 1.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031392 Uncertain Uncertain "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "Cell Junctions" "HPA031392: AB_10601935" "unprognostic (6.81e-2)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (1.34e-1)" "unprognostic (1.36e-1)" "unprognostic (6.54e-5)" "unprognostic (4.16e-2)" "unprognostic (4.85e-7)" "unprognostic (3.95e-2)" "unprognostic (7.72e-4)" "unprognostic (1.93e-1)" "unprognostic (1.68e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Group enriched" "Detected in some" 4 "Astrocytes: 15.0;Early spermatids: 8.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.3;PC-3: 1.3;SiHa: 3.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" 0.0 0.0 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.0 0.4 0.0 0.2 1.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.7 0.4 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.7 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.5 0.0 0.2 0.0 0.3 1.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 3.5 0.0 0.4 0.1 0.4 0.0 0.1 0.1 1.9 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.2 0.1 0.3 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.0 15.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.3 0.3 0.2 0.0 0.0 0.0 1.5 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 17.9 0.0 0.1 0.0 1.0 0.0 1.3 0.0 13.0 2.9 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.1 0.6 1.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 GPR157 FLJ12132 ENSG00000180758 "G protein-coupled receptor 157" Q5UAW9 1 9100305-9129102 "G-protein coupled receptors, Predicted membrane proteins" Differentiation "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 59.6" "Cell type enhanced" "Detected in many" "Langerhans cells: 268.1;monocytes: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Karpas-707: 31.8;SK-BR-3: 62.7;U-266/70: 30.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA028697 Uncertain Uncertain "Nucleoli,Nucleoli rim,Plasma membrane,Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 59: Non-specific - Translation" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 41: Macrophages - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Cell Junctions" "HPA028697: AB_10601810" "unprognostic (2.83e-3)" "unprognostic (1.13e-2)" "unprognostic (5.91e-2)" "unprognostic (5.42e-2)" "unprognostic (2.13e-4)" "unprognostic (7.11e-2)" "unprognostic (7.52e-3)" "unprognostic (3.60e-2)" "unprognostic (9.20e-2)" "unprognostic (1.26e-1)" "unprognostic (9.13e-3)" "unprognostic (1.42e-1)" "unprognostic (1.02e-2)" "unprognostic (1.70e-2)" "unprognostic (1.21e-1)" "unprognostic (4.30e-2)" "unprognostic (3.04e-3)" 3.3 4.8 0.7 4.4 0.8 1.3 3.3 1.1 1.2 7.9 10.7 3.1 4.0 2.9 1.3 30.2 2.9 2.0 12.9 1.4 0.6 2.3 9.0 6.7 3.1 1.7 0.9 4.3 4.1 15.1 1.4 8.7 1.2 3.5 2.2 0.9 8.9 2.3 59.6 22.6 2.8 1.7 0.7 3.9 3.7 2.0 1.1 2.5 3.3 23.9 7.5 6.7 13.7 1.0 9.0 5.0 1.5 4.1 1.4 1.3 8.0 2.8 1.8 2.3 3.1 4.1 3.4 1.1 3.4 3.0 2.9 18.9 4.6 1.8 3.4 25.2 7.6 0.1 16.0 6.2 4.9 0.1 2.0 1.2 3.9 3.9 2.4 2.3 1.8 3.7 1.4 31.8 0.9 6.5 3.8 1.9 1.7 4.4 6.3 0.6 1.3 4.3 1.4 6.0 2.3 6.1 10.8 62.7 5.2 3.0 8.9 1.1 13.3 7.8 2.0 20.5 1.3 30.6 5.2 0.1 5.8 12.6 3.3 0.7 0.4 0.1 0.6 0.3 0.5 0.4 0.4 0.6 0.2 0.6 0.4 0.5 1.2 0.2 0.1 0.2 0.2 0.2 0.7 0.8 1.1 1.2 1.4 0.6 1.7 0.9 1.2 0.7 1.1 1.0 3.1 6.4 8.9 0.0 5.3 13.6 10.2 17.8 12.5 0.7 14.7 8.4 13.4 2.8 12.3 5.5 2.1 34.8 2.9 6.8 0.0 3.5 0.1 13.7 6.9 4.0 0.0 0.0 1.4 3.9 10.0 4.8 5.1 26.5 0.0 3.2 2.5 14.8 4.0 1.7 1.2 4.8 10.2 0.8 268.1 0.2 1.8 13.1 7.2 0.0 107.4 1.0 0.0 0.0 0.2 13.9 4.3 5.3 4.7 6.8 7.5 1.6 7.4 1.4 0.0 5.5 4.2 0.6 2.3 43.6 24.3 48.2 3.5 5.0 5.5 16.1 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.4" "Cell type enhanced" "Detected in some" "Astrocytes: 43.4;Excitatory neurons: 19.7;Inhibitory neurons: 14.1;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 42.3" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavorable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favorable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" 2.2 2.7 12.6 1.4 11.7 1.0 2.0 14.5 12.5 6.6 4.6 4.2 0.6 5.5 2.1 1.0 6.4 1.4 4.0 12.3 14.2 2.9 0.4 2.6 1.0 10.9 13.6 12.0 0.8 1.1 18.4 2.1 13.3 4.0 1.1 7.0 1.3 2.3 2.4 1.7 2.1 1.9 9.3 3.3 1.9 1.5 14.5 1.5 1.8 1.0 0.4 3.2 3.6 12.0 0.0 0.0 7.8 0.8 4.1 2.4 0.3 1.4 2.7 2.0 2.3 0.8 0.1 0.2 1.9 2.6 5.9 0.8 9.5 0.0 1.7 0.9 1.3 0.6 9.3 0.3 6.0 0.5 0.2 5.8 0.0 3.0 4.1 6.6 3.2 0.2 0.0 5.4 2.9 4.6 0.2 0.1 6.2 0.4 3.5 0.2 2.6 0.7 0.4 0.4 5.8 7.9 0.0 0.8 0.0 4.7 1.2 0.2 5.7 3.4 5.0 2.6 1.1 0.2 0.7 0.8 2.5 0.0 1.8 3.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.2 0.6 0.8 0.2 0.3 0.1 0.0 12.6 11.7 14.5 12.5 12.3 14.2 10.9 13.6 13.3 9.3 14.5 12.0 0.5 0.0 0.0 43.4 0.2 0.3 0.4 0.6 0.0 6.6 0.1 0.3 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 5.2 1.1 3.5 0.0 19.7 0.0 0.0 1.5 0.0 0.3 0.0 7.1 1.8 0.1 0.2 6.7 14.1 0.4 0.0 0.3 0.7 0.0 3.1 0.2 1.8 11.2 0.0 3.2 0.0 49.3 42.3 0.1 0.0 4.5 0.0 0.3 0.0 0.1 0.1 3.1 0.0 2.0 2.5 0.1 0.2 0.0 0.0 0.1 0.1 2.8 0.1 0.2 GPR174 FKSG79 ENSG00000147138 "G protein-coupled receptor 174" Q9BXC1 X 79144688-79175318 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "lymphoid tissue: 16.9" "Cell type enhanced" "Detected in some" "B-cells: 6.6;dendritic cells: 30.6;Plasma cells: 4.2;T-cells: 18.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "JURKAT: 42.3;MOLT-4: 75.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA041025, HPA058306" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Vesicles, Centriolar satellite" "HPA041025: AB_10794260, HPA058306: " "unprognostic (6.38e-3)" "unprognostic (9.87e-3)" "unprognostic (4.36e-2)" "unprognostic (1.18e-2)" "unprognostic (1.84e-1)" "unprognostic (8.48e-4)" "unprognostic (7.12e-2)" "unprognostic (1.05e-2)" "unprognostic (1.75e-1)" "unprognostic (2.02e-1)" "unprognostic (2.46e-1)" "unprognostic (1.05e-1)" "unprognostic (6.53e-5)" "unprognostic (2.27e-1)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "unprognostic (1.78e-2)" 0.8 0.4 0.5 6.9 0.3 2.5 0.9 0.6 0.6 0.4 0.3 1.0 2.0 0.5 0.6 0.3 0.3 1.1 0.3 0.4 0.4 0.5 1.0 1.9 15.2 0.7 0.5 0.2 0.1 0.1 0.1 0.2 0.7 0.7 1.6 0.2 1.5 0.1 0.2 0.2 3.6 0.3 0.3 8.1 2.1 0.1 0.4 16.9 0.9 0.1 10.4 1.4 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.3 0.0 1.2 0.0 0.0 75.1 0.1 0.0 0.0 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.2 0.0 0.0 0.0 6.5 0.0 3.6 3.6 2.0 1.2 2.5 4.8 6.1 0.1 2.6 4.2 4.9 0.3 4.6 5.5 1.0 4.8 1.6 0.5 0.3 0.6 0.6 0.4 0.4 0.7 0.5 0.7 0.3 0.4 0.5 0.7 0.0 2.4 0.0 6.6 0.1 0.0 0.0 0.0 0.0 0.7 0.6 0.0 0.0 0.6 1.8 0.0 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.1 0.0 3.1 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 18.5 0.1 0.0 0.0 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 72.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Cell line enriched" "Detected in single" 6 "EFO-21: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 0.8 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.4 2.0 0.0 1.4 0.4 1.9 0.7 0.6 1.5 0.7 1.1 0.0 0.0 0.6 0.2 1.5 0.0 0.0 0.0 1.2 0.2 0.1 0.2 1.2 0.1 0.9 0.3 0.0 0.2 0.8 0.3 0.4 2.1 1.8 0.0 0.2 1.7 0.1 0.0 0.0 0.5 0.4 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.2 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 72.3 0.3 16.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 GPR27 SREB1 ENSG00000170837 "G protein-coupled receptor 27" Q9NS67 3 71753855-71756496 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 22.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 10.3;Breast myoepithelial cells: 7.5;Collecting duct cells: 12.9;Glandular and luminal cells: 8.1;monocytes: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 2.8;neutrophil: 7.2" "Lineage enriched" "Detected in single" 12 "granulocytes: 7.2" "Cell line enhanced" "Detected in some" "EFO-21: 17.9;HL-60: 17.5;MCF7: 14.6;NTERA-2: 28.9;RPTEC TERT1: 13.6;SH-SY5Y: 10.9;T-47d: 9.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029395 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA029395: AB_10602907" "prognostic favorable (5.63e-4)" "unprognostic (2.99e-1)" "unprognostic (3.23e-2)" "unprognostic (3.22e-1)" "unprognostic (7.14e-3)" "unprognostic (1.50e-2)" "unprognostic (2.17e-2)" "unprognostic (1.18e-2)" "unprognostic (3.22e-1)" "prognostic favorable (1.21e-6)" "unprognostic (2.97e-3)" "unprognostic (4.97e-2)" "unprognostic (1.51e-2)" "unprognostic (1.21e-2)" "unprognostic (2.71e-2)" "unprognostic (1.45e-2)" "unprognostic (6.79e-2)" 1.4 4.0 21.3 1.5 22.9 15.7 3.9 13.0 19.7 3.5 7.4 1.6 0.3 5.0 2.8 3.7 6.8 1.0 3.4 19.9 20.6 3.2 0.1 1.4 0.2 18.0 18.3 4.4 3.1 17.3 9.2 1.2 16.2 5.1 0.5 1.8 1.4 4.3 0.7 2.1 0.7 2.9 19.7 3.3 2.0 4.7 22.9 0.5 6.2 1.9 0.2 2.0 2.3 18.9 0.0 1.1 1.9 2.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 17.9 0.0 0.8 0.1 4.3 0.0 0.0 0.0 7.8 0.0 0.0 0.0 0.1 17.5 0.9 0.0 2.9 0.0 1.2 0.0 0.0 3.7 0.0 0.0 0.0 14.6 1.2 0.2 28.9 0.0 0.0 0.0 0.0 0.0 13.6 7.8 3.0 10.9 3.8 0.0 0.0 3.6 9.9 0.0 0.0 0.0 7.7 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.5 2.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.1 7.2 0.0 0.1 0.0 0.0 0.1 21.3 22.9 13.0 19.7 19.9 20.6 18.0 18.3 16.2 19.7 22.9 18.9 0.2 0.0 1.1 0.0 0.1 1.9 4.2 0.0 4.0 10.3 6.5 7.5 3.5 2.8 1.3 12.9 4.2 1.4 0.4 0.2 1.9 0.7 0.2 2.1 4.9 0.4 1.2 1.7 0.0 0.0 1.3 1.2 1.1 8.1 0.0 2.4 0.4 0.0 0.9 0.0 0.0 0.0 0.0 4.4 0.3 0.0 0.9 3.2 0.0 0.0 8.6 0.5 1.0 0.0 0.0 0.3 0.1 1.2 0.0 5.6 0.0 0.1 1.5 0.4 0.0 2.3 1.7 0.2 4.8 4.7 1.7 0.3 0.7 0.5 0.3 2.0 GPR37L1 ETBR-LP-2 ENSG00000170075 "G protein-coupled receptor 37 like 1" O60883 1 202122917-202133592 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 76.4" "Cell type enhanced" "Detected in some" "Astrocytes: 91.7;Muller glia cells: 59.6;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 20.4" "Cancer enriched" "Detected in some" 57 "glioma: 36.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HaCaT: 1.2;MCF7: 1.5;T-47d: 3.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA061629, HPA064454" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 6: T47d - Mammary gland" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cell Junctions" "Vesicles, Plasma membrane" "HPA061629: , HPA064454: AB_2685268" "unprognostic (2.12e-2)" "unprognostic (1.83e-1)" "unprognostic (2.96e-1)" "unprognostic (1.61e-3)" "unprognostic (4.52e-1)" "unprognostic (8.20e-2)" "unprognostic (2.26e-4)" "unprognostic (5.83e-2)" "unprognostic (3.46e-3)" "unprognostic (2.07e-1)" "unprognostic (1.83e-1)" "unprognostic (3.28e-2)" "unprognostic (4.86e-3)" "unprognostic (1.14e-1)" "unprognostic (4.58e-2)" "unprognostic (1.18e-3)" "unprognostic (3.49e-1)" 0.1 0.2 55.2 0.0 71.1 0.2 0.0 60.7 52.2 0.2 10.6 0.9 0.2 0.1 0.1 0.1 0.1 0.0 0.1 48.0 50.7 0.0 0.2 0.0 0.0 66.7 67.0 0.0 0.0 0.0 0.6 0.0 53.7 0.2 0.2 2.8 0.1 0.3 0.1 0.1 0.3 0.1 59.4 0.0 0.2 0.3 76.4 0.0 0.1 0.1 0.0 0.0 0.1 53.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 55.2 71.1 60.7 52.2 48.0 50.7 66.7 67.0 53.7 59.4 76.4 53.1 0.0 0.0 0.0 91.7 0.1 0.4 0.5 0.7 0.0 1.2 0.3 0.3 1.1 1.5 1.7 0.0 4.2 0.1 0.0 4.9 0.0 3.2 4.5 0.9 0.2 0.1 0.0 0.0 0.4 1.2 1.0 0.2 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.5 1.1 0.0 0.0 0.0 0.8 0.9 0.1 0.0 2.8 0.0 59.6 0.0 89.0 20.4 2.1 2.7 1.9 0.0 0.8 1.3 0.1 1.1 4.9 0.0 0.5 0.1 0.0 0.1 0.0 0.1 0.7 0.1 0.2 0.7 1.0 GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 17.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEK 293: 5.0;SuSa: 4.0" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 10 "hypothalamus: 4.8" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA049862: AB_2680920, HPA054678: AB_2682570" "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 17.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.6 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR63 "PSP24(beta), PSP24B" ENSG00000112218 "G protein-coupled receptor 63" Q9BZJ6 6 96794125-96837477 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "Early spermatids: 31.4;Excitatory neurons: 46.2;Granulosa cells: 31.2;Inhibitory neurons: 20.3;Late spermatids: 35.2;Spermatocytes: 24.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 8.8;HHSteC: 13.5;Karpas-707: 20.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039103 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA039103: AB_10672841" "unprognostic (8.22e-2)" "unprognostic (2.77e-1)" "unprognostic (1.71e-2)" "unprognostic (1.02e-2)" "unprognostic (1.83e-1)" "unprognostic (1.33e-1)" "unprognostic (2.65e-2)" "unprognostic (1.15e-1)" "unprognostic (3.39e-1)" "unprognostic (2.53e-2)" "unprognostic (7.29e-3)" "unprognostic (3.00e-1)" "unprognostic (2.03e-3)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.34e-1)" "unprognostic (2.30e-2)" 0.5 0.9 1.4 0.7 3.5 0.1 0.4 0.7 2.7 1.5 2.7 1.2 1.5 0.5 0.3 0.5 0.7 0.7 0.5 1.5 0.1 0.3 0.0 0.3 0.1 1.6 0.6 1.0 1.4 1.0 0.9 0.7 2.0 0.9 1.8 0.2 0.4 0.5 0.2 0.4 1.1 0.6 0.0 0.3 1.1 2.4 0.9 0.6 0.6 0.1 0.2 0.8 1.4 1.8 0.0 0.1 1.6 0.4 2.3 0.8 0.4 1.0 0.0 0.0 0.2 0.2 1.2 0.1 0.0 0.1 1.3 1.2 5.4 2.5 0.0 8.8 4.1 5.2 0.4 0.0 13.5 3.3 0.6 2.5 0.4 0.0 3.7 0.3 0.0 7.6 3.8 20.8 0.5 0.4 2.5 0.0 5.4 0.0 0.7 0.0 1.9 4.3 0.3 0.2 2.4 1.5 0.3 3.3 0.6 1.7 1.3 0.7 0.0 1.4 2.1 0.2 2.0 1.6 0.9 0.1 0.8 2.0 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.2 0.0 0.1 0.0 0.0 1.4 3.5 0.7 2.7 1.5 0.1 1.6 0.6 2.0 0.0 0.9 1.8 0.6 0.0 0.0 2.3 0.2 1.9 0.7 0.3 4.0 1.5 0.6 0.9 0.7 2.8 0.1 1.8 0.0 0.2 0.3 0.1 0.0 0.4 31.4 0.1 0.5 0.7 3.0 0.4 46.2 0.9 0.7 2.5 1.1 0.1 0.0 31.2 1.1 0.0 0.2 0.0 20.3 0.5 0.0 0.0 8.9 35.2 3.4 0.4 1.8 9.4 0.1 0.2 0.0 11.6 4.8 0.4 0.1 4.9 1.0 1.1 0.1 0.2 0.0 0.2 0.0 0.4 2.2 24.6 10.5 1.9 0.3 0.1 0.4 2.1 0.5 0.3 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRIN1 "GRIN1, KIAA1893" ENSG00000169258 "G protein regulated inducer of neurite outgrowth 1" Q7Z2K8 5 176595802-176610156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 8.1;retina: 6.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 12.8;Excitatory neurons: 7.5;Horizontal cells: 21.9;Inhibitory neurons: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 56.5;SCLC-21H: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036478, HPA070892" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Vesicles "HPA036478: AB_2675145, HPA070892: AB_2686321" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.41e-2)" "unprognostic (5.66e-2)" "unprognostic (6.54e-3)" "unprognostic (3.06e-1)" "unprognostic (4.76e-6)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.11e-1)" "unprognostic (1.45e-1)" "unprognostic (2.59e-3)" "unprognostic (1.56e-3)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.24e-3)" "unprognostic (5.60e-2)" "unprognostic (2.21e-1)" "unprognostic (3.32e-3)" 0.5 1.6 16.9 0.8 15.9 0.2 0.3 6.8 19.5 0.3 0.0 1.1 3.8 0.4 0.0 0.8 0.1 0.3 0.4 22.1 15.7 0.6 0.4 0.4 0.8 4.3 3.5 0.0 0.6 0.1 8.1 0.3 5.1 0.2 0.4 6.9 0.3 0.0 0.3 1.0 3.2 0.7 3.3 0.4 0.8 1.5 14.8 0.9 0.2 0.2 1.1 0.3 0.2 6.6 7.5 7.9 9.8 14.1 2.1 4.6 8.3 9.8 5.1 7.5 9.7 9.6 4.8 17.0 19.6 5.3 22.0 6.5 6.3 6.8 6.5 56.5 4.3 0.3 4.1 3.4 0.9 0.4 4.2 2.3 5.1 8.1 1.2 1.5 5.5 3.8 9.1 24.0 6.3 19.7 1.8 0.0 9.9 5.0 15.4 31.7 10.9 10.1 8.4 7.7 59.5 34.1 11.4 3.2 17.7 1.2 7.4 6.5 6.8 13.8 16.0 5.3 14.5 0.4 2.3 4.8 11.9 0.8 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 15.9 6.8 19.5 22.1 15.7 4.3 3.5 5.1 3.3 14.8 6.6 0.4 0.0 0.0 0.3 0.5 2.4 0.1 0.3 0.6 12.8 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.3 1.9 0.4 0.0 0.5 0.6 1.0 1.8 0.0 7.5 1.8 0.9 0.4 0.0 1.2 0.0 0.3 0.0 0.0 0.9 21.9 8.0 0.3 0.0 0.0 0.3 0.0 0.3 0.2 0.0 1.9 0.1 1.1 1.0 2.5 0.3 1.6 0.1 0.0 0.8 0.2 0.0 0.3 0.4 3.1 0.0 1.5 0.3 0.7 2.7 0.4 1.4 0.1 0.3 0.4 0.2 0.1 GPRIN2 "KIAA0514, MGC15171" ENSG00000204175 "G protein regulated inducer of neurite outgrowth 2" O60269 10 46549044-46555530 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 10.5;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 19.2;Distal enterocytes: 30.4;Exocrine glandular cells: 20.2;Intestinal goblet cells: 30.8;Late spermatids: 20.6;Proximal enterocytes: 21.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "A-431: 10.2;A549: 13.1;SiHa: 3.7;SK-BR-3: 12.0" "Low region specificity" "Detected in many" "HPA038129, HPA070760" Approved Approved "Plasma membrane,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA038129: AB_2675846, HPA070760: " "unprognostic (1.00e-2)" "unprognostic (1.91e-1)" "unprognostic (1.77e-2)" "prognostic unfavorable (8.60e-8)" "unprognostic (5.77e-2)" "prognostic favorable (3.47e-4)" "unprognostic (2.23e-1)" "unprognostic (2.67e-2)" "unprognostic (2.54e-1)" "unprognostic (1.27e-1)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.97e-2)" "unprognostic (1.98e-2)" "unprognostic (2.37e-1)" "unprognostic (1.23e-1)" "unprognostic (5.67e-3)" 0.1 0.0 1.7 0.6 1.6 0.0 0.9 5.9 2.1 0.9 0.4 6.2 3.6 0.0 0.0 4.4 0.3 0.2 0.0 0.6 6.7 5.7 0.3 10.5 0.0 5.5 4.9 0.1 5.7 2.1 4.2 0.0 5.7 1.9 3.4 0.1 2.8 1.1 0.1 17.4 8.0 0.1 1.8 0.0 5.1 3.0 9.7 0.0 3.4 0.0 0.5 0.6 2.0 1.0 10.2 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.2 0.0 0.7 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.9 0.0 0.0 0.0 0.0 1.7 0.3 0.3 0.1 3.7 12.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.9 2.1 0.6 6.7 5.5 4.9 5.7 1.8 9.7 1.0 0.0 19.2 3.7 0.0 0.0 1.7 2.8 1.9 2.8 0.3 1.4 1.0 0.2 7.2 2.1 3.7 0.0 0.0 0.0 30.4 0.0 11.3 9.3 0.0 0.0 0.1 6.6 0.0 0.7 20.2 0.0 0.1 3.6 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.9 30.8 0.0 0.0 0.3 20.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 12.6 13.1 0.4 0.0 2.1 21.7 4.0 1.8 0.1 0.0 0.0 0.2 2.9 0.8 2.4 6.1 0.0 0.1 0.0 7.3 1.3 GPX8 "EPLA847, UNQ847" ENSG00000164294 "Glutathione peroxidase 8 (putative)" Q8TED1 5 55160167-55167297 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Oxidoreductase, Peroxidase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 62.7;Extravillous trophoblasts: 218.9;Fibroblasts: 76.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 254.4;fHDF/TERT166: 246.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036720 Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Actin filaments" "HPA036720: AB_2675269" "unprognostic (4.85e-2)" "unprognostic (1.23e-2)" "unprognostic (6.53e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-2)" "unprognostic (9.74e-3)" "unprognostic (1.78e-2)" "unprognostic (1.63e-3)" "unprognostic (2.07e-2)" "unprognostic (4.34e-2)" "unprognostic (4.31e-2)" "unprognostic (8.68e-2)" "prognostic unfavorable (5.13e-9)" "prognostic unfavorable (7.96e-4)" "unprognostic (8.11e-2)" "unprognostic (1.16e-2)" "unprognostic (2.63e-2)" 13.3 6.1 1.2 12.5 1.2 0.1 12.6 1.2 1.6 37.1 6.9 7.3 2.9 21.1 21.9 6.2 14.3 17.0 11.2 1.0 1.7 6.5 2.2 6.9 3.8 1.5 1.1 27.3 4.6 9.3 2.4 39.7 1.4 10.2 8.4 1.3 7.2 15.8 1.5 5.0 4.1 27.2 1.5 4.0 5.6 5.6 1.2 1.3 22.3 6.3 3.0 17.8 9.8 3.6 37.2 39.0 75.3 77.0 180.7 223.9 36.6 179.8 254.4 97.0 192.7 3.2 82.1 0.0 199.0 246.4 86.5 28.2 46.0 51.5 131.5 0.5 17.3 2.1 49.1 6.9 64.4 0.0 0.0 157.5 60.8 68.3 35.5 126.5 122.7 0.0 1.1 0.1 137.4 14.4 0.0 0.0 32.6 1.0 42.8 0.1 40.2 0.0 65.9 1.3 0.1 1.4 56.6 4.6 68.0 80.8 56.6 3.4 102.7 63.6 65.6 84.5 102.3 0.1 0.5 0.5 103.0 0.1 118.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.2 1.6 1.0 1.7 1.5 1.1 1.4 1.5 1.2 3.6 10.9 0.0 1.1 0.3 0.3 7.1 6.0 38.3 9.1 0.2 8.9 6.1 4.3 0.0 33.3 25.8 0.0 49.5 0.2 0.5 5.9 13.7 0.4 6.5 62.7 18.6 0.0 0.0 0.1 38.8 218.9 76.6 2.6 4.9 4.5 30.9 19.2 0.2 10.2 0.0 0.1 4.7 4.1 0.0 6.9 0.6 51.3 1.1 24.9 5.6 1.1 7.9 0.0 0.0 0.1 15.8 0.3 39.9 1.4 2.6 0.1 0.5 36.5 0.3 13.1 20.1 38.2 0.1 0.4 3.1 6.1 13.3 1.8 29.9 0.9 2.4 GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" 37.9 36.9 17.8 28.0 15.9 23.9 31.1 16.4 24.5 33.2 17.5 30.1 15.1 32.5 5.3 11.6 36.2 16.5 30.3 17.4 18.5 27.4 21.2 58.1 28.8 21.8 20.7 38.4 80.8 17.8 29.2 16.8 21.5 32.6 8.4 5.1 55.6 17.0 47.8 14.5 23.3 18.9 18.2 42.1 35.8 16.6 21.5 18.7 25.4 18.9 12.8 35.7 20.1 17.1 17.3 106.0 21.3 41.5 23.9 27.5 19.6 21.6 27.5 21.8 21.6 39.8 11.9 10.8 41.2 25.2 19.3 9.5 22.2 31.9 8.2 48.9 47.3 24.6 25.5 36.8 48.3 21.7 41.1 46.5 19.9 16.1 26.7 36.6 71.5 54.1 31.8 5.7 16.0 13.2 46.5 23.6 38.6 28.4 12.7 47.1 6.9 10.7 24.8 2.5 30.8 64.4 20.0 12.7 33.7 18.4 19.4 20.6 38.9 34.9 22.3 8.0 29.6 8.8 26.3 22.4 23.5 19.6 27.0 23.1 5.7 5.4 3.5 9.6 7.3 0.6 4.6 2.7 5.1 1.2 3.5 5.4 12.7 5.7 19.9 1.7 4.1 3.8 17.8 15.9 16.4 24.5 17.4 18.5 21.8 20.7 21.5 18.2 21.5 17.1 51.0 22.4 37.3 28.1 23.6 20.8 64.4 15.1 18.2 15.8 22.0 18.7 12.3 0.0 16.1 16.5 16.7 13.1 32.3 3.5 3.9 36.8 1.4 15.3 19.9 63.2 39.4 20.4 8.9 57.8 35.8 25.6 10.7 16.5 9.5 39.5 66.4 5.6 53.8 8.4 12.1 15.0 14.2 39.4 81.6 3.0 25.7 37.7 33.8 15.0 146.0 23.1 19.6 12.5 15.1 41.2 9.6 25.2 40.4 68.6 1.4 15.1 11.5 14.9 13.1 15.4 26.0 1.2 5.7 3.4 15.3 33.1 48.1 50.6 19.7 51.9 GRAMD1B "KIAA1201, LINC01059" ENSG00000023171 "GRAM domain containing 1B" Q3KR37 11 123358428-123627774 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.8;choroid plexus: 91.8;retina: 96.7" "Cell type enhanced" "Detected in many" "Astrocytes: 94.7;Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Inhibitory neurons: 102.8;Oligodendrocyte precursor cells: 95.0;Rod photoreceptor cells: 92.3;Theca cells: 109.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 7.0" "Lineage enriched" "Detected in many" 4 "dendritic cells: 7.0" "Group enriched" "Detected in many" 4 "A549: 62.4;HDLM-2: 168.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008557, HPA075204" Approved Supported "Endoplasmic reticulum,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum, Plasma membrane" Vesicles "HPA008557: AB_1079197, HPA075204: " "unprognostic (1.86e-1)" "unprognostic (7.18e-3)" "unprognostic (2.43e-2)" "unprognostic (2.74e-3)" "unprognostic (8.15e-2)" "unprognostic (4.28e-2)" "unprognostic (2.69e-3)" "unprognostic (4.12e-3)" "unprognostic (1.40e-1)" "unprognostic (2.90e-2)" "unprognostic (9.60e-2)" "unprognostic (8.06e-2)" "prognostic unfavorable (4.30e-7)" "unprognostic (1.39e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (1.69e-1)" 1.8 258.8 22.5 4.3 27.4 18.6 1.1 80.1 52.3 0.9 91.8 1.6 34.6 1.1 9.4 0.6 3.6 12.1 15.0 55.6 19.4 15.5 1.5 2.6 5.4 25.7 20.1 15.2 2.4 0.7 16.6 5.0 24.2 1.1 1.1 96.7 1.9 2.0 3.4 0.5 25.2 1.2 9.4 3.6 11.4 16.8 33.5 6.6 4.9 2.2 3.5 1.2 0.8 26.1 0.1 62.4 3.5 0.1 0.3 0.7 9.5 20.5 14.6 4.1 1.8 2.6 0.4 3.8 10.4 10.1 6.8 0.0 6.2 0.0 4.3 168.5 5.0 0.0 28.3 0.7 0.0 22.1 0.0 1.0 0.1 7.1 0.0 5.2 1.8 1.6 0.0 0.2 3.7 0.5 3.8 7.2 7.6 28.3 23.0 10.8 9.8 6.8 0.2 0.0 20.0 16.3 4.9 0.5 0.1 8.1 0.5 12.0 12.3 23.8 3.2 4.2 1.0 0.0 0.0 0.0 4.6 20.5 1.1 0.0 1.2 0.4 0.4 0.7 0.2 0.0 1.5 1.2 1.7 0.0 0.2 0.2 0.1 1.6 0.7 7.0 0.7 0.5 22.5 27.4 80.1 52.3 55.6 19.4 25.7 20.1 24.2 9.4 33.5 26.1 1.4 0.0 0.5 94.7 0.6 0.0 0.0 0.1 1.2 44.3 1.1 1.0 5.7 21.5 0.2 5.5 114.7 6.9 17.9 0.1 3.9 0.7 9.6 1.6 0.6 1.0 0.0 0.0 120.7 0.4 3.7 1.6 16.3 0.9 0.0 41.9 0.7 0.0 2.6 45.4 102.8 1.8 0.0 3.8 2.6 2.7 0.6 7.5 0.0 37.5 2.5 23.4 0.0 95.0 5.5 3.9 1.3 0.7 2.4 0.1 17.3 8.9 0.4 92.3 0.0 3.0 4.2 3.9 1.9 0.1 0.4 2.5 7.2 109.3 1.5 0.0 GRAMD1C DKFZp434C0328 ENSG00000178075 "GRAM domain containing 1C" Q8IYS0 3 113828182-113947174 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 181.8;Early spermatids: 97.1;Late spermatids: 80.5;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 2.7;naive B-cell: 2.9;neutrophil: 2.1" "Group enriched" "Detected in many" 13 "B-cells: 2.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.5;HUVEC TERT2: 10.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012316 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA012316: AB_1849949" "unprognostic (2.73e-3)" "unprognostic (6.16e-3)" "unprognostic (3.27e-1)" "unprognostic (1.93e-1)" "unprognostic (5.50e-2)" "unprognostic (9.81e-3)" "unprognostic (1.43e-3)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (5.49e-2)" "prognostic favorable (4.22e-15)" "unprognostic (8.48e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-2)" "unprognostic (2.09e-2)" 1.4 1.9 13.0 1.7 12.0 0.1 8.8 11.9 15.3 3.1 9.0 5.0 7.6 2.2 2.0 5.5 10.7 2.6 0.7 11.6 12.1 24.0 27.7 4.9 2.0 13.9 15.4 0.8 12.7 10.6 8.1 6.1 11.8 2.6 3.9 14.3 12.0 2.1 0.8 12.1 16.7 0.7 12.3 1.3 9.0 16.8 14.5 1.1 3.9 3.2 3.9 2.0 3.7 10.0 1.6 0.0 4.0 3.0 0.7 1.8 5.2 3.5 3.1 0.7 2.1 0.0 13.5 0.4 1.0 2.0 1.4 1.3 0.7 1.5 1.8 1.9 0.6 0.3 0.1 0.0 1.4 0.2 0.0 3.0 1.0 0.6 0.1 7.1 10.2 4.5 0.0 0.1 1.1 0.4 1.6 0.2 0.3 1.4 0.5 0.0 0.8 2.4 4.2 1.9 0.8 1.1 1.0 5.2 3.4 1.6 3.6 0.0 2.2 1.5 2.8 0.0 0.3 2.2 1.3 1.9 2.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 0.2 0.0 2.9 0.1 0.1 2.1 0.1 0.0 0.0 0.0 0.0 13.0 12.0 11.9 15.3 11.6 12.1 13.9 15.4 11.8 12.3 14.5 10.0 4.5 12.8 10.5 181.8 15.6 1.0 6.9 3.0 5.2 0.2 9.9 7.0 0.9 15.7 7.1 14.7 37.5 17.5 0.3 10.1 31.3 4.4 97.1 33.3 8.5 4.7 4.9 2.7 29.7 2.7 3.7 1.5 6.6 51.9 0.0 1.4 5.7 17.0 1.5 11.8 4.3 5.5 4.1 0.3 0.8 80.5 2.8 0.9 1.8 9.4 0.1 13.4 0.0 82.4 1.7 2.3 9.3 1.5 6.3 2.8 34.3 14.0 27.9 19.7 0.0 1.2 1.7 28.2 6.7 6.8 4.7 42.4 1.9 5.0 5.3 7.0 GRAP2 "GADS, GRBLG, GrbX, Grf40, Mona" ENSG00000100351 "GRB2 related adaptor protein 2" O75791 22 39901084-39973721 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "lymphoid tissue: 184.8" "Cell type enhanced" "Detected in many" "Erythroid cells: 32.6;granulocytes: 146.9;Macrophages: 82.0;NK-cells: 59.8;T-cells: 57.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 7 "gdT-cell: 51.4;MAIT T-cell: 38.2;memory CD4 T-cell: 37.5;memory CD8 T-cell: 56.2;naive CD4 T-cell: 31.3;naive CD8 T-cell: 58.2;T-reg: 35.0" "Lineage enriched" "Detected in many" 9 "T-cells: 58.2" "Group enriched" "Detected in some" 4 "HEL: 45.7;JURKAT: 175.8;K-562: 44.8;MOLT-4: 122.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA005788, CAB022073" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 290000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022073: , HPA005788: AB_1079021" "unprognostic (1.96e-4)" "unprognostic (1.82e-4)" "unprognostic (4.19e-2)" "unprognostic (8.91e-4)" "unprognostic (2.92e-2)" "unprognostic (5.56e-5)" "unprognostic (1.27e-2)" "unprognostic (8.41e-3)" "unprognostic (4.69e-2)" "unprognostic (9.29e-2)" "unprognostic (5.17e-3)" "unprognostic (2.83e-2)" "unprognostic (1.75e-3)" "unprognostic (2.10e-1)" "unprognostic (2.20e-2)" "unprognostic (1.34e-1)" "unprognostic (8.06e-2)" 1.2 0.7 0.2 7.9 0.2 10.3 2.0 0.2 0.3 1.5 0.5 2.2 3.6 0.8 0.5 1.2 0.7 2.6 1.1 0.2 0.3 0.6 1.2 4.4 15.7 0.6 0.3 0.2 0.4 0.1 0.3 0.6 0.5 1.6 2.3 0.3 1.7 0.7 0.4 1.1 4.5 0.9 0.5 9.3 3.8 1.9 0.4 184.8 0.8 0.5 12.9 3.0 1.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 45.7 0.0 0.0 0.0 0.0 6.9 0.0 0.1 0.0 0.2 0.3 0.0 175.8 44.8 0.0 0.0 0.0 122.8 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.8 6.3 0.7 0.1 51.4 0.3 38.2 3.1 37.5 56.2 1.2 5.2 31.3 58.2 6.6 5.4 0.3 0.8 35.0 74.9 0.2 0.2 0.2 0.3 0.2 0.3 0.6 0.3 0.5 0.5 0.4 0.7 1.1 0.0 6.7 0.3 8.2 1.7 0.0 0.0 0.0 0.6 1.1 0.8 1.0 2.8 0.0 0.0 0.0 0.0 18.3 0.1 0.0 0.4 4.8 0.3 0.1 0.8 1.2 32.6 1.3 0.2 0.0 0.6 0.0 0.1 146.9 0.2 2.5 2.3 0.2 0.0 1.2 0.6 0.0 1.9 4.6 2.9 0.3 82.0 1.8 1.0 6.8 0.3 59.8 2.5 1.0 0.0 0.3 0.4 6.3 0.4 0.0 0.4 0.0 0.0 0.0 0.5 0.9 4.4 2.1 0.1 1.1 0.1 57.1 0.0 0.1 0.3 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6497462-6551436 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 31.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 2.9;Oligodendrocyte precursor cells: 4.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 31.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "REH: 3.6" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA045381: AB_10962495" "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (3.39e-4)" "unprognostic (1.19e-3)" "unprognostic (5.52e-2)" "unprognostic (2.50e-2)" "unprognostic (2.82e-1)" "unprognostic (2.37e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.54e-2)" "unprognostic (8.08e-2)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" 0.0 0.4 6.7 0.1 6.2 0.2 0.2 10.7 1.4 0.1 0.0 0.3 0.4 0.1 0.0 0.3 0.2 0.1 0.1 0.1 7.9 0.2 0.0 0.2 0.1 2.4 9.8 0.1 0.5 0.5 0.9 0.0 1.9 0.5 0.1 0.5 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.3 0.4 0.3 31.9 0.2 0.3 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.3 0.0 3.6 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 10.7 1.4 0.1 7.9 2.4 9.8 1.9 0.0 31.9 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.6 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.5 0.1 0.0 0.1 0.0 0.4 2.8 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 4.5 1.3 0.1 0.0 0.0 0.3 0.2 0.4 0.1 0.0 1.0 0.0 0.0 0.1 0.8 0.2 1.2 0.0 0.0 0.1 0.9 0.1 0.2 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42069498 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;testis: 32.9" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Bipolar cells: 23.0;Excitatory neurons: 32.4;Horizontal cells: 18.5;Inhibitory neurons: 31.1;Oligodendrocyte precursor cells: 31.7;Rod photoreceptor cells: 21.2" "Group enriched" "Detected in many" 5 "glioma: 15.4;ovarian cancer: 6.6;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.7;hTERT-RPE1: 21.2;NTERA-2: 13.1;REH: 37.5;SCLC-21H: 10.3;SH-SY5Y: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA074001: AB_2732248" "unprognostic (4.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.30e-3)" "unprognostic (6.68e-3)" "unprognostic (4.28e-2)" "unprognostic (3.86e-1)" "unprognostic (5.82e-1)" "unprognostic (2.23e-1)" "unprognostic (3.89e-2)" "unprognostic (1.73e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.43e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (6.47e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-2)" "unprognostic (6.12e-2)" 1.6 4.0 20.0 1.7 17.3 3.0 1.2 6.2 26.7 5.3 0.1 16.4 0.7 7.3 1.8 1.6 6.8 1.9 4.9 36.5 15.5 7.0 0.3 0.5 0.7 3.6 4.8 3.6 2.7 14.8 18.3 0.0 7.0 6.2 1.0 12.5 0.7 6.5 0.5 0.9 3.4 5.2 3.0 1.3 5.3 32.9 14.6 0.9 11.3 0.7 0.6 5.0 2.7 6.6 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.3 13.7 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 21.2 0.0 0.6 0.1 0.6 0.0 0.2 0.2 0.0 13.1 0.1 0.0 37.5 0.0 0.1 5.8 0.1 10.3 22.7 0.1 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 17.3 6.2 26.7 36.5 15.5 3.6 4.8 7.0 3.0 14.6 6.6 0.2 0.0 0.0 17.9 0.1 0.4 0.1 0.0 0.0 23.0 0.2 0.8 3.1 0.0 0.0 1.8 2.1 0.0 0.0 0.1 0.0 0.8 1.6 0.2 0.2 0.4 0.0 0.0 32.4 0.0 0.0 0.6 0.0 0.3 4.5 7.2 0.0 0.0 0.0 18.5 31.1 0.0 0.0 0.0 0.0 2.3 0.9 0.1 0.0 2.8 0.0 9.1 0.0 31.7 0.9 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 21.2 0.0 4.9 1.7 4.2 2.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963571-3040760 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.3;testis: 42.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 123.0;Early spermatids: 357.7;Late spermatids: 500.3;Spermatocytes: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057023 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA057023: AB_2683313" "unprognostic (1.86e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (3.65e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (3.90e-4)" "unprognostic (3.20e-1)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" 2.8 3.3 6.2 1.1 6.2 1.3 2.4 19.3 8.4 3.0 0.3 2.8 1.0 2.7 2.3 1.8 2.1 2.4 4.9 6.5 5.7 2.2 2.0 2.0 1.2 6.0 5.5 3.5 5.4 4.4 6.2 1.6 5.7 2.0 1.4 10.1 2.9 2.1 4.8 2.3 1.4 2.1 3.6 1.4 3.0 42.3 6.4 1.6 3.3 4.4 1.2 2.3 2.2 7.2 2.3 0.8 2.7 7.9 6.3 6.1 1.6 4.3 1.9 2.4 2.1 2.3 0.7 5.1 1.9 7.1 4.8 0.7 3.6 3.6 2.1 3.4 3.4 5.6 3.2 2.6 3.8 2.3 1.9 4.1 5.7 4.3 2.0 2.7 4.7 5.5 5.4 6.6 5.8 2.6 4.8 4.8 2.1 3.3 6.0 6.1 3.4 2.1 2.3 2.9 15.2 4.8 2.7 1.2 4.1 1.9 6.0 3.5 5.5 6.6 1.7 4.5 4.0 6.5 4.0 3.8 3.3 5.0 2.2 2.1 0.3 0.6 0.3 0.7 0.4 0.3 0.2 0.2 0.1 0.3 0.5 0.4 1.1 0.5 0.2 0.7 0.1 0.4 6.2 6.2 19.3 8.4 6.5 5.7 6.0 5.5 5.7 3.6 6.4 7.2 3.9 3.2 7.4 34.6 2.1 11.2 3.2 5.0 7.4 57.1 5.0 5.5 11.4 4.3 5.6 3.7 123.0 2.1 4.7 0.8 13.7 2.7 357.7 4.2 7.2 4.2 10.3 8.6 53.9 3.8 5.3 8.7 5.1 3.8 5.7 75.0 6.1 3.0 3.4 18.5 71.1 2.4 4.1 2.9 4.6 500.3 13.1 3.1 7.2 9.4 3.0 11.4 2.1 48.2 29.3 2.1 0.4 8.2 5.3 1.8 2.0 5.0 1.2 58.2 6.6 8.4 5.7 180.4 22.3 6.5 11.4 3.0 4.0 34.6 1.3 2.4 GRK5 GPRK5 ENSG00000198873 "G protein-coupled receptor kinase 5" P34947 10 119207571-119459745 "Enzymes, Predicted intracellular proteins" "Apoptosis, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Microglial cells: 56.2;Sertoli cells: 59.2;Smooth muscle cells: 46.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 32.1;HUVEC TERT2: 24.9;OE19: 25.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025579, HPA046838" Approved Supported "Nuclear membrane,Nuclear speckles,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 21: OE19 - Mitochondria" "Cluster 50: Fibroblasts - ECM organization" "Nuclear membrane, Nuclear speckles" "Plasma membrane" "CAB025579: , HPA046838: AB_2679833" "unprognostic (1.09e-1)" "unprognostic (3.47e-1)" "unprognostic (1.19e-1)" "unprognostic (6.02e-2)" "unprognostic (6.56e-2)" "unprognostic (3.74e-2)" "unprognostic (4.62e-2)" "unprognostic (3.69e-1)" "unprognostic (4.11e-1)" "unprognostic (1.06e-1)" "unprognostic (3.70e-1)" "unprognostic (2.32e-1)" "prognostic unfavorable (2.38e-7)" "unprognostic (1.10e-1)" "unprognostic (3.27e-2)" "unprognostic (1.55e-2)" "unprognostic (1.90e-2)" 38.4 18.0 4.2 5.9 5.0 2.7 24.6 5.0 4.6 18.8 3.5 26.3 10.0 21.1 3.5 12.6 19.6 5.7 48.8 4.0 5.1 14.2 12.9 65.6 7.8 3.9 3.6 35.0 4.7 21.3 13.3 8.3 3.9 14.1 4.9 1.0 7.8 4.0 11.9 11.5 25.8 7.3 3.3 37.0 27.5 4.1 4.9 6.2 19.6 9.7 6.8 19.4 18.1 3.5 3.7 2.3 5.4 5.7 11.8 11.0 1.6 7.1 32.1 4.1 2.3 1.7 5.4 3.9 1.6 11.1 7.5 0.9 2.3 7.7 2.7 15.4 2.0 0.7 4.6 7.0 8.2 0.2 2.0 1.5 1.1 8.5 1.2 5.2 24.9 2.4 0.4 3.7 1.5 0.7 3.8 3.5 0.8 25.8 5.2 1.3 0.8 0.9 0.6 1.5 1.8 4.9 2.4 1.1 7.0 3.0 0.1 0.9 7.8 2.3 1.6 14.6 2.8 0.9 4.4 2.4 4.9 4.4 2.4 0.4 1.5 2.9 2.0 1.4 0.1 3.8 3.0 1.6 0.9 4.0 4.5 2.0 2.1 0.1 0.5 0.0 4.0 1.7 4.2 5.0 5.0 4.6 4.0 5.1 3.9 3.6 3.9 3.3 4.9 3.5 32.6 57.7 3.7 3.6 19.7 1.7 0.7 0.5 1.2 3.9 2.3 2.0 19.4 0.0 1.3 3.7 0.0 3.7 13.3 0.4 0.0 1.1 18.7 0.4 5.1 28.4 4.8 0.0 17.7 3.1 15.8 35.7 18.8 1.0 4.5 7.8 24.7 2.2 4.4 1.7 36.5 0.8 6.1 15.5 6.3 4.9 4.4 14.2 7.2 56.2 3.6 0.0 19.6 14.1 5.7 2.4 1.2 4.5 10.2 0.7 4.9 0.6 0.8 0.9 59.2 18.2 46.5 1.3 2.1 0.7 2.4 13.1 14.1 4.6 0.5 0.9 GRPR "BB2, BB2R" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 20.3" "Cell type enriched" "Detected in single" 15 "Inhibitory neurons: 6.3" "Cancer enriched" "Detected in some" 4 "breast cancer: 6.6" "Region enhanced" "Detected in some" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "PC-3: 29.2;T-47d: 38.2;U-138 MG: 51.5" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA069604: AB_2686158" "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" 0.1 0.1 0.1 0.2 0.2 0.1 1.9 0.0 0.3 0.3 0.1 0.4 0.1 0.5 1.9 0.0 0.1 0.1 0.2 0.2 1.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 20.3 0.2 0.0 0.1 0.2 0.5 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.8 1.1 0.1 1.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.3 0.0 0.9 0.1 4.0 1.6 0.4 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.5 0.0 0.0 0.0 0.5 0.0 29.2 0.0 0.1 0.1 0.1 0.0 0.8 0.1 0.0 0.1 0.1 1.5 38.2 0.1 0.2 51.5 1.9 0.0 1.6 0.3 0.2 0.2 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.2 1.6 0.3 0.0 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GSDMA "FLJ39120, GSDM, GSDM1" ENSG00000167914 "Gasdermin A" Q96QA5 17 39953263-39977768 "Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "skin 1: 58.9" "Group enriched" "Detected in some" 5 "Collecting duct cells: 3.7;Hofbauer cells: 5.0;Kupffer cells: 5.6;Macrophages: 2.6;Suprabasal keratinocytes: 2.7;Theca cells: 2.8" "Cancer enhanced" "Detected in many" "head and neck cancer: 7.6" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HBEC3-KT: 4.1;hTCEpi: 2.7;hTERT-HME1: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA023313, HPA064826" Enhanced Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 44000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA023313: AB_1850378, HPA064826: AB_2685361" "unprognostic (1.32e-2)" "unprognostic (2.01e-1)" "unprognostic (2.95e-2)" "unprognostic (1.06e-1)" "unprognostic (3.62e-1)" "unprognostic (1.97e-1)" "unprognostic (7.77e-2)" "unprognostic (1.39e-1)" "unprognostic (3.24e-1)" "unprognostic (3.52e-2)" "unprognostic (2.71e-1)" "unprognostic (2.90e-2)" "unprognostic (1.06e-2)" "unprognostic (9.86e-2)" "unprognostic (7.45e-2)" "unprognostic (3.63e-2)" "unprognostic (3.79e-2)" 3.4 0.7 0.2 0.9 0.2 0.4 3.5 0.4 0.4 0.8 0.2 0.7 0.6 0.4 6.6 3.2 0.3 0.8 0.3 0.3 0.2 0.3 0.3 0.4 0.7 0.4 0.0 0.1 0.3 1.3 0.1 1.6 0.4 0.1 1.2 0.0 0.8 0.0 0.4 58.9 0.5 0.6 0.0 0.2 0.3 0.3 0.4 0.5 0.1 0.1 3.4 1.1 1.5 0.4 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 4.1 0.0 0.1 0.2 0.5 0.4 0.2 0.0 0.1 0.8 0.0 2.7 0.5 5.4 0.0 0.0 0.0 0.1 1.3 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.4 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.9 0.1 0.1 2.2 0.0 2.6 0.0 1.3 0.8 0.1 0.1 0.6 0.9 0.7 0.1 0.1 0.2 0.5 0.5 0.2 0.2 0.4 0.4 0.3 0.2 0.4 0.0 0.4 0.0 0.4 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.7 0.0 5.0 0.0 0.1 0.7 0.0 5.6 0.6 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 2.7 0.0 0.2 2.8 0.0 0.0 GTF2F1 "BTF4, RAP74, TF2F1, TFIIF" ENSG00000125651 "General transcription factor IIF subunit 1" P35269 19 6379572-6393981 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 228.3;Late spermatids: 391.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022793, HPA028707, HPA070752" Supported Enhanced "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 16: U-266 - Nucleosome" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Vesicles, Cell Junctions" "HPA022793: AB_1857946, HPA028707: AB_2672745, HPA070752: AB_2732163" "unprognostic (1.30e-2)" "unprognostic (6.05e-3)" "unprognostic (2.00e-1)" "prognostic favorable (8.39e-4)" "unprognostic (3.18e-1)" "unprognostic (8.46e-2)" "unprognostic (1.05e-1)" "unprognostic (1.38e-1)" "unprognostic (1.23e-1)" "unprognostic (5.99e-2)" "unprognostic (6.45e-3)" "unprognostic (6.96e-2)" "prognostic favorable (9.80e-4)" "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.92e-2)" "unprognostic (4.25e-1)" 35.0 38.1 36.7 34.0 38.4 71.0 34.2 43.6 43.0 48.8 30.2 41.2 40.5 48.5 25.9 46.0 44.8 36.1 32.8 39.1 35.8 37.6 30.0 31.5 43.5 34.4 34.3 73.6 57.5 42.6 49.8 26.8 34.6 39.5 23.3 24.9 43.8 31.7 36.8 36.8 39.2 25.1 30.1 36.4 43.9 68.3 36.1 37.1 49.6 22.6 29.8 37.3 41.0 36.1 115.6 97.1 62.0 100.9 46.5 73.1 47.3 81.7 84.7 112.0 106.0 104.4 48.5 76.3 111.9 67.2 73.5 109.9 69.3 65.6 57.1 106.6 90.1 97.2 60.7 86.9 78.6 107.1 79.5 82.8 78.2 85.5 64.1 86.4 69.0 72.9 115.9 91.7 63.9 96.2 115.4 79.7 108.2 59.7 124.3 101.5 68.0 94.6 67.5 74.2 76.1 99.8 83.0 64.5 95.6 36.4 84.0 94.0 79.8 78.5 62.6 134.0 110.1 153.9 197.2 79.7 98.1 124.9 91.0 10.2 29.7 20.8 26.1 28.4 29.7 32.9 23.5 24.9 23.3 31.6 27.0 24.6 40.1 27.6 30.2 30.3 25.4 19.8 36.7 38.4 43.6 43.0 39.1 35.8 34.4 34.3 34.6 30.1 36.1 36.1 29.2 48.1 56.6 5.2 51.9 24.3 50.2 40.5 53.5 27.6 43.1 34.7 28.9 32.9 58.4 25.8 8.4 46.1 51.6 88.2 21.5 48.5 228.3 70.5 70.7 41.0 30.5 51.7 6.9 50.8 43.0 43.3 51.0 57.4 63.8 32.7 58.9 26.0 60.2 25.2 7.0 53.4 24.4 54.8 25.9 391.6 44.4 42.1 33.8 5.6 66.0 35.6 49.4 3.5 4.9 47.4 66.0 49.7 55.4 29.9 65.3 48.8 83.6 33.5 32.9 44.8 52.9 71.8 38.3 44.9 21.0 54.0 48.3 41.8 54.4 40.6 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42155406-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 91 "retina: 804.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 667.2;Late spermatids: 432.4;Muller glia cells: 219.9;Rod photoreceptor cells: 1191.6" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.9" "Group enriched" "Detected in some" 8 "NTERA-2: 3.8;SH-SY5Y: 4.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA005561: AB_2667361, HPA075056: " "unprognostic (1.91e-2)" "unprognostic (3.92e-3)" "unprognostic (2.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.04e-4)" "unprognostic (9.70e-2)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (3.08e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" 0.0 0.0 1.5 0.1 3.5 0.1 0.0 0.9 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 5.4 0.0 0.0 0.0 0.1 1.5 1.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 804.8 0.0 0.0 0.1 0.1 0.1 0.1 0.8 0.0 0.0 8.8 6.2 0.0 0.0 0.0 0.2 0.0 0.1 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.0 0.0 4.9 0.0 0.0 1.5 3.5 0.9 1.8 1.3 5.4 1.5 1.4 1.4 0.8 6.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 140.7 0.0 0.0 0.3 0.0 0.0 0.0 667.2 0.6 1.3 0.0 0.0 0.0 106.5 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 65.6 1.0 0.0 4.1 0.0 0.0 432.4 1.8 0.1 0.0 0.0 5.2 219.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 1191.6 0.0 0.0 1.2 3.2 3.9 0.0 0.0 0.3 0.0 0.1 0.0 0.1 GYPA "CD235a, GPA, MN, MNS" ENSG00000170180 "Glycophorin A (MNS blood group)" P02724 4 144109303-144140751 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Host-virus interaction" "Blood group antigen, Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 38 "bone marrow: 156.3" "Cell type enriched" "Detected in some" 350 "Erythroid cells: 1995.6" "Not detected" "Not detected" "Region enriched" "Detected in single" 5 "cerebral cortex: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 203 "HEL: 149.1;K-562: 37.7" "CAB002658, HPA014811" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 15000000 "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane, Cytosol" "CAB002658: , HPA014811: AB_1849827" "unprognostic (1.60e-1)" "unprognostic (2.47e-2)" 0.1 0.1 0.1 0.0 0.1 156.3 0.0 0.0 1.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 2.3 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 149.1 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.7 0.0 0.0 0.0 0.0 1995.6 2.4 0.0 2.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 2.1 0.0 1.7 0.0 0.0 0.9 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.6 0.2 0.0 0.0 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HARBI1 "C11orf77, FLJ32675" ENSG00000180423 "Harbinger transposase derived 1" Q96MB7 11 46602861-46617909 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 70.9;Late spermatids: 73.0;Spermatocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038671, HPA045457" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA038671: AB_10675947, HPA045457: AB_2679332" "unprognostic (1.29e-1)" "unprognostic (6.82e-2)" "unprognostic (7.76e-2)" "unprognostic (2.65e-1)" "unprognostic (1.61e-1)" "unprognostic (3.95e-1)" "unprognostic (1.23e-5)" "unprognostic (2.10e-1)" "unprognostic (1.66e-2)" "unprognostic (9.58e-2)" "unprognostic (3.15e-1)" "unprognostic (6.34e-2)" "unprognostic (6.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (5.01e-2)" "unprognostic (1.13e-1)" 2.0 2.6 2.6 2.4 4.5 5.6 2.4 3.3 4.2 2.3 2.3 3.0 2.6 1.7 3.4 2.3 2.1 2.0 2.5 2.7 3.1 2.9 3.3 2.2 3.4 3.5 3.5 1.4 2.4 2.2 2.5 2.8 3.6 2.2 3.4 2.7 2.8 1.9 2.6 3.2 2.8 3.0 2.8 2.4 4.0 12.1 4.0 4.2 2.7 2.0 3.4 2.6 1.5 7.3 3.3 5.3 4.3 4.1 8.4 5.1 5.1 4.7 4.5 6.3 8.0 3.7 3.7 5.8 2.9 3.9 7.1 6.3 4.6 4.1 5.9 6.7 5.5 5.9 3.9 4.2 9.8 5.5 7.6 6.5 10.7 4.2 8.2 2.4 4.0 6.2 9.4 7.0 5.3 7.1 6.8 2.3 11.8 10.8 6.4 4.5 6.1 10.3 4.8 3.9 4.1 3.4 5.6 5.9 6.8 5.7 9.9 4.7 3.8 6.3 4.9 8.4 4.3 6.6 7.7 6.3 4.8 3.2 6.6 21.9 7.6 10.9 9.6 10.3 6.7 4.7 7.6 7.0 6.4 6.6 7.2 8.0 11.2 6.9 9.8 8.3 10.2 4.4 2.6 4.5 3.3 4.2 2.7 3.1 3.5 3.5 3.6 2.8 4.0 7.3 1.0 0.0 1.3 1.3 2.2 1.0 2.7 4.0 1.8 3.5 2.5 1.8 2.3 1.5 4.4 0.0 2.1 4.9 1.5 2.1 5.9 4.1 70.9 4.7 2.2 1.4 1.2 13.5 1.5 2.2 3.4 1.7 2.0 4.7 0.0 1.6 1.8 2.8 3.3 3.3 1.5 2.2 8.2 3.3 0.8 73.0 3.1 1.7 1.8 0.0 4.2 2.9 1.0 0.5 4.6 3.0 0.8 1.9 3.4 1.6 3.4 3.5 6.1 3.7 0.0 2.1 2.0 25.2 13.5 1.7 2.7 9.3 2.2 2.2 1.7 2.3 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.6;ovary: 20.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 26.6;Bipolar cells: 20.3;Cholangiocytes: 38.6;Fibroblasts: 64.2;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "U-87 MG: 112.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA067602: AB_2685871" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 49.6 0.5 1.4 6.3 1.1 3.6 1.3 1.1 1.1 0.1 0.0 2.8 0.1 1.0 0.0 0.8 9.0 5.5 9.2 0.9 2.0 0.5 0.6 3.7 0.0 1.8 0.8 20.8 2.1 0.3 0.9 0.3 0.7 0.2 0.5 0.2 0.2 0.0 0.2 5.4 1.3 0.7 0.3 0.3 1.7 0.3 2.2 0.1 0.7 0.0 0.0 6.3 0.6 1.3 0.0 0.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 3.2 0.0 27.0 0.0 0.1 0.0 0.0 0.0 0.2 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.3 0.8 0.0 0.0 0.0 0.0 112.6 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 1.1 1.1 1.1 0.9 2.0 1.8 0.8 0.7 0.3 2.2 1.3 1.5 0.0 1.8 0.0 0.2 26.6 0.1 0.8 0.6 20.3 0.0 0.0 1.3 38.6 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.5 0.0 0.0 1.7 0.0 0.2 64.2 2.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.8 9.0 0.2 0.3 8.3 8.8 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.5 0.0 3.1 10.6 0.1 0.5 0.4 17.8 0.1 0.3 0.0 0.0 0.2 HAUS7 "UCHL5IP, UIP1" ENSG00000213397 "HAUS augmin like complex subunit 7" Q99871 X 153447666-153495516 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003614 Approved "Plasma membrane,Centrosome" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome" "HPA003614: AB_1080368" "unprognostic (2.06e-1)" "prognostic favorable (6.12e-4)" "unprognostic (3.81e-2)" "unprognostic (3.21e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-2)" "unprognostic (1.75e-2)" "unprognostic (7.50e-2)" "unprognostic (1.56e-1)" "unprognostic (3.39e-1)" "unprognostic (4.65e-3)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (4.25e-2)" "unprognostic (1.09e-2)" 19.0 13.0 29.1 9.2 31.3 11.0 16.2 26.3 54.0 42.3 24.3 15.9 7.1 17.8 15.1 11.4 21.3 13.2 23.5 32.3 26.3 25.2 13.6 19.5 14.4 28.3 27.0 16.0 8.2 5.0 11.9 12.3 28.4 22.5 5.8 3.0 12.5 17.9 12.0 44.7 13.3 11.5 26.4 28.5 11.5 12.6 29.0 10.4 19.2 9.2 9.5 17.4 21.7 32.3 28.2 44.9 24.1 51.2 8.9 14.1 37.2 17.8 12.1 30.1 51.4 36.2 17.3 25.5 59.2 18.5 43.1 32.0 39.6 29.4 15.6 23.6 59.6 19.3 33.5 26.9 9.3 26.9 35.5 21.1 7.4 29.5 16.4 13.1 22.4 32.5 21.7 17.6 15.7 68.9 41.7 60.5 15.7 67.5 65.8 36.5 30.2 47.0 10.2 17.3 25.1 20.5 10.3 27.4 9.6 8.9 10.8 20.8 10.7 27.1 42.9 50.8 36.1 24.0 33.7 97.6 11.7 68.9 34.6 14.8 53.2 22.7 32.6 66.7 34.5 44.0 36.1 33.6 46.7 36.5 35.2 32.2 6.7 39.1 62.0 26.0 33.8 34.3 29.1 31.3 26.3 54.0 32.3 26.3 28.3 27.0 28.4 26.4 29.0 32.3 9.4 6.4 8.1 45.4 5.3 7.1 1.6 3.6 1.2 2.1 2.7 3.0 2.5 4.3 2.6 0.0 4.2 12.6 6.0 9.3 5.9 10.4 0.1 1.0 1.8 5.6 2.4 6.6 11.9 8.0 24.6 6.3 3.6 0.7 19.7 1.6 15.4 4.2 12.2 3.3 4.9 13.8 4.1 10.0 6.8 0.5 5.9 5.0 3.6 4.7 13.4 2.0 12.3 31.7 3.5 7.4 7.7 7.5 2.5 3.3 6.9 14.9 3.5 1.9 6.6 1.9 6.5 2.2 6.7 1.3 4.7 9.3 4.9 1.7 14.9 1.5 HCAR2 "GPR109A, HCA2, HM74A, NIACR1, Puma-g, PUMAG" ENSG00000182782 "Hydroxycarboxylic acid receptor 2" Q8TDS4 12 122701293-122703357 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" Apoptosis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 40.8;skin 1: 30.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 84.7;Basal respiratory cells: 52.0;Basal squamous epithelial cells: 120.1;Ionocytes: 87.5;Langerhans cells: 124.0;Suprabasal keratinocytes: 106.1" "Group enriched" "Detected in many" 8 "cervical cancer: 12.6;head and neck cancer: 16.1;lung cancer: 6.4;urothelial cancer: 9.2" "Region enriched" "Detected in some" 5 "cerebral cortex: 5.9" "Immune cell enriched" "Detected in many" 5 "neutrophil: 176.7" "Lineage enriched" "Detected in many" 7 "granulocytes: 176.7" "Cell line enriched" "Detected in some" 6 "HaCaT: 118.4" HPA028660 Approved Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (5.43e-2)" "unprognostic (1.27e-1)" "unprognostic (1.77e-1)" "unprognostic (2.05e-1)" "unprognostic (6.65e-2)" "unprognostic (1.33e-1)" "unprognostic (3.33e-3)" "unprognostic (7.26e-2)" "unprognostic (2.17e-1)" "unprognostic (1.77e-2)" "unprognostic (7.10e-2)" "unprognostic (7.33e-2)" "unprognostic (4.83e-4)" "unprognostic (5.76e-2)" "unprognostic (5.07e-2)" "unprognostic (1.54e-1)" "unprognostic (4.63e-2)" 22.2 0.3 0.1 9.8 0.2 22.1 7.6 0.1 5.9 8.9 0.2 0.7 0.9 0.2 0.3 40.8 0.7 0.8 0.9 0.3 0.1 3.9 2.9 11.9 0.6 0.1 0.1 0.1 0.2 5.5 0.3 4.5 1.2 3.4 0.3 0.2 14.2 14.7 0.2 30.2 1.0 0.3 0.1 25.9 1.5 2.7 0.2 10.5 0.5 1.9 10.2 6.9 14.0 0.1 4.5 0.4 0.1 0.1 1.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 118.4 0.0 7.3 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.3 0.1 3.8 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.3 0.0 0.0 0.4 0.1 0.0 0.0 0.0 19.5 0.2 0.0 0.4 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.3 0.0 0.0 38.7 2.5 2.6 0.0 5.3 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 176.7 0.0 23.9 0.0 0.0 1.4 0.1 0.2 0.1 5.9 0.3 0.1 0.1 0.1 1.2 0.1 0.2 0.1 0.4 0.0 4.3 0.0 0.5 94.4 84.7 52.0 120.1 0.5 3.4 1.1 0.1 0.0 40.3 0.0 0.0 1.5 0.0 0.0 0.0 0.0 24.9 0.4 0.2 1.2 0.0 0.0 0.0 0.0 26.3 2.4 0.0 0.3 2.5 0.0 0.0 0.0 3.7 0.0 0.0 0.0 87.5 4.1 124.0 2.7 0.0 17.8 8.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 8.5 0.1 0.0 0.1 1.4 0.0 0.1 47.2 106.1 2.6 1.5 0.0 0.0 32.5 HCAR3 "GPR109B, HCA3, HM74" ENSG00000255398 "Hydroxycarboxylic acid receptor 3" P49019 12 122714756-122716811 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 27.4;esophagus: 16.8;lymphoid tissue: 19.6;skin 1: 17.4" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 94.4;Basal prostatic cells: 81.1;Basal respiratory cells: 57.3;Basal squamous epithelial cells: 159.4;Langerhans cells: 57.4;Squamous epithelial cells: 66.9;Suprabasal keratinocytes: 106.3;Urothelial cells: 66.1" "Group enriched" "Detected in some" 4 "cervical cancer: 2.1;head and neck cancer: 2.5;lung cancer: 1.0;urothelial cancer: 1.9" "Region enriched" "Detected in single" 5 "cerebral cortex: 4.7" "Group enriched" "Detected in many" 6 "basophil: 58.6;neutrophil: 177.2;non-classical monocyte: 84.4" "Group enriched" "Detected in many" 50 "granulocytes: 177.2;monocytes: 84.4" "Cell line enriched" "Detected in some" 4 "RT4: 37.1" HPA028660 Approved Approved "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 15: RT4 - Unknown function" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions" "HPA028660: AB_10602139" "unprognostic (2.32e-1)" "unprognostic (5.82e-2)" "unprognostic (8.23e-2)" "unprognostic (2.27e-1)" "unprognostic (1.17e-1)" "unprognostic (9.17e-2)" "unprognostic (1.64e-3)" "unprognostic (1.60e-1)" "unprognostic (6.29e-2)" "unprognostic (9.87e-2)" "unprognostic (1.50e-2)" "unprognostic (2.80e-1)" "unprognostic (1.23e-1)" "unprognostic (2.30e-2)" "unprognostic (2.83e-1)" "unprognostic (1.16e-1)" "unprognostic (9.28e-2)" 5.6 0.1 0.0 9.2 0.1 27.4 2.3 0.0 4.7 2.5 0.2 0.5 0.2 0.0 0.5 16.8 0.7 0.6 0.7 0.1 0.0 0.9 1.8 8.2 0.4 0.0 0.0 0.1 0.0 3.4 0.2 1.9 0.9 1.5 0.1 0.1 3.4 2.7 0.1 17.4 0.2 0.2 0.0 19.6 0.4 0.1 0.1 4.0 0.4 1.1 7.8 7.1 4.3 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 9.2 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 37.1 0.2 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.1 58.6 2.2 0.8 0.0 16.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.1 177.2 0.0 84.4 0.0 0.0 2.9 0.0 0.1 0.0 4.7 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.0 0.1 3.2 6.7 0.0 0.7 94.4 81.1 57.3 159.4 0.2 0.7 0.3 0.0 0.0 24.6 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 21.5 1.4 0.0 0.1 3.8 0.0 0.0 0.1 6.0 0.0 0.0 0.0 12.2 10.6 57.4 0.2 0.0 20.1 8.8 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 14.7 0.0 0.1 2.2 0.2 0.0 0.0 1.4 0.1 0.0 66.9 106.3 13.8 1.0 0.0 0.0 66.1 HCFC2 HCF-2 ENSG00000111727 "Host cell factor C2" Q9Y5Z7 12 104064531-104106524 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 250.3;Spermatocytes: 130.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006227 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA006227: AB_1079042" "unprognostic (4.22e-3)" "unprognostic (1.22e-1)" "unprognostic (1.08e-1)" "unprognostic (7.66e-2)" "unprognostic (3.15e-2)" "unprognostic (2.11e-2)" "unprognostic (1.46e-1)" "unprognostic (1.07e-2)" "unprognostic (1.59e-1)" "unprognostic (1.43e-2)" "unprognostic (2.71e-2)" "unprognostic (4.54e-2)" "unprognostic (4.23e-3)" "unprognostic (1.16e-2)" "unprognostic (2.24e-1)" "unprognostic (1.19e-2)" "unprognostic (7.23e-2)" 6.3 6.7 3.8 3.6 5.2 2.7 5.1 4.4 5.4 7.4 2.0 9.2 5.2 7.9 5.0 6.2 5.3 5.7 5.1 3.7 4.2 5.7 7.3 4.7 4.6 4.9 5.0 7.8 6.0 6.7 4.1 6.4 4.8 7.2 4.3 8.0 4.5 9.4 9.7 4.4 5.0 7.2 4.7 5.1 5.2 9.5 4.6 5.2 6.9 11.2 3.7 5.9 6.0 6.6 2.0 2.3 2.3 2.0 12.7 12.5 1.7 9.1 4.1 6.8 3.9 1.1 0.9 2.1 3.1 7.1 2.5 2.2 2.9 1.6 7.3 3.5 2.8 2.1 2.3 1.0 8.5 1.7 3.3 7.8 4.3 4.2 3.5 9.8 5.3 3.1 2.5 4.2 12.3 1.8 3.1 4.0 0.5 1.3 4.7 2.5 7.6 1.3 3.1 1.4 3.3 2.5 4.4 3.2 3.5 1.5 5.0 1.9 8.0 10.7 1.4 5.6 3.1 5.3 1.7 1.8 5.1 2.3 4.4 0.4 0.6 0.9 0.8 1.1 0.9 0.5 0.7 0.9 0.7 0.5 0.8 0.9 0.1 0.8 1.8 0.4 0.9 0.5 3.8 5.2 4.4 5.4 3.7 4.2 4.9 5.0 4.8 4.7 4.6 6.6 19.3 12.8 14.1 18.9 10.0 8.0 6.6 5.4 8.6 19.6 6.1 5.0 12.5 1.5 9.6 5.5 20.9 5.0 8.8 7.4 9.8 6.2 250.3 7.9 18.5 14.4 8.4 7.4 31.8 3.3 5.0 16.0 6.6 6.5 17.1 9.8 15.7 11.5 7.4 23.5 33.9 4.7 8.2 11.4 5.7 59.4 21.8 8.6 7.2 16.9 9.3 13.7 7.2 30.7 45.6 3.1 6.0 27.8 12.2 2.7 7.7 8.6 10.4 22.2 13.1 18.7 17.4 130.9 16.4 8.5 7.2 10.8 11.3 17.9 3.8 3.3 HCK JTK9 ENSG00000101336 "HCK proto-oncogene, Src family tyrosine kinase" P08631 20 32052197-32101856 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Exocytosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity, Phagocytosis" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 112.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 150.7;Kupffer cells: 155.5;Langerhans cells: 89.2;Macrophages: 170.1;Microglial cells: 52.5;monocytes: 222.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 16 "classical monocyte: 575.0;eosinophil: 707.8;intermediate monocyte: 1059.1;myeloid DC: 336.3;neutrophil: 801.3;non-classical monocyte: 1251.7" "Group enriched" "Detected in all" 16 "dendritic cells: 336.3;granulocytes: 801.3;monocytes: 1251.7" "Group enriched" "Detected in some" 9 "THP-1: 69.3;U-937: 199.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB005195, HPA035534, HPA063768" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane, Cytosol" "CAB005195: AB_631619, HPA035534: , HPA063768: AB_2685118" "unprognostic (6.22e-2)" "unprognostic (6.16e-3)" "unprognostic (2.26e-2)" "unprognostic (7.98e-2)" "unprognostic (8.83e-2)" "unprognostic (5.50e-2)" "unprognostic (4.09e-2)" "unprognostic (1.72e-2)" "unprognostic (4.34e-2)" "unprognostic (1.59e-1)" "unprognostic (4.08e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.66e-4)" "unprognostic (4.92e-2)" "unprognostic (4.42e-2)" "unprognostic (6.95e-2)" "unprognostic (1.12e-1)" 24.8 9.2 4.7 100.0 5.0 55.2 6.0 5.5 6.0 5.5 13.7 12.8 15.2 3.1 2.6 6.7 7.6 14.4 4.8 4.7 6.2 4.7 14.1 46.0 38.6 9.9 6.8 2.5 4.5 2.1 3.1 20.9 8.3 4.0 13.6 0.5 5.1 4.7 1.6 5.8 17.8 25.3 8.1 112.1 6.7 2.3 8.4 14.5 2.8 6.9 39.3 32.8 4.1 12.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.9 0.0 0.1 0.1 1.3 0.0 0.0 0.1 0.0 4.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 15.6 0.0 0.1 0.1 4.9 0.4 0.0 0.0 0.4 0.2 0.6 0.0 0.0 0.3 0.0 0.5 0.0 0.2 0.7 0.0 69.3 0.0 0.0 0.3 0.0 0.1 1.9 0.3 10.3 0.0 199.6 0.0 6.4 575.0 707.8 1.1 1059.1 1.3 48.4 1.1 1.1 336.3 43.0 1.1 0.9 801.3 11.0 1251.7 30.4 1.2 566.4 4.7 5.0 5.5 6.0 4.7 6.2 9.9 6.8 8.3 8.1 8.4 12.0 0.6 6.4 14.0 0.0 17.1 3.1 4.0 0.2 0.6 0.1 0.4 1.3 2.0 1.5 3.9 7.3 0.0 0.9 12.1 0.2 1.9 0.1 2.5 0.1 0.1 3.7 1.8 1.7 1.2 0.6 0.9 1.3 4.6 0.1 6.3 0.1 1.1 2.3 150.7 0.0 1.0 0.5 22.4 155.5 89.2 0.3 0.0 170.1 1.8 52.5 222.0 0.0 4.1 1.5 0.6 0.0 0.0 0.0 0.7 0.5 0.1 0.3 1.5 0.1 0.0 0.6 0.5 0.2 0.3 0.2 1.1 1.6 3.0 0.2 0.9 3.7 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HCST "DAP10, DKFZP586C1522, KAP10, PIK3AP" ENSG00000126264 "Hematopoietic cell signal transducer" Q9UBK5 19 35902529-35904377 "Metabolic proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 253.7;lymphoid tissue: 115.6" "Cell type enhanced" "Detected in many" "dendritic cells: 993.2;Hofbauer cells: 571.1;Kupffer cells: 396.6;Langerhans cells: 584.5;Macrophages: 392.7;NK-cells: 1687.0;T-cells: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 239.9;HL-60: 139.6;HMC-1: 154.3;THP-1: 177.8;U-937: 272.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB034435, HPA063026" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB034435: AB_2117803, HPA063026: " "unprognostic (1.40e-3)" "unprognostic (3.07e-2)" "unprognostic (3.04e-2)" "unprognostic (7.27e-3)" "unprognostic (1.23e-1)" "unprognostic (8.23e-3)" "unprognostic (1.85e-1)" "unprognostic (2.54e-1)" "prognostic favorable (6.70e-4)" "unprognostic (5.97e-2)" "unprognostic (1.94e-3)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.59e-10)" "unprognostic (3.78e-1)" "unprognostic (3.25e-2)" "unprognostic (1.65e-1)" "unprognostic (1.56e-1)" 27.2 9.5 14.0 53.6 13.8 253.7 14.1 13.7 18.5 9.6 16.6 12.7 11.3 8.3 4.7 5.5 9.9 11.5 8.3 13.5 17.0 10.6 14.5 40.3 68.0 18.3 14.7 5.7 6.7 2.5 9.6 24.7 17.6 9.4 8.6 2.2 10.7 8.2 4.2 6.6 28.2 11.2 17.1 115.6 15.4 3.4 18.2 59.6 7.9 3.0 37.8 16.4 8.0 22.2 0.9 0.0 0.3 0.5 1.1 0.0 0.3 1.9 1.1 0.0 0.6 0.8 1.2 26.9 1.7 2.0 0.4 0.9 0.0 0.2 0.0 0.6 0.0 239.9 0.5 0.7 0.9 139.6 154.3 1.6 0.3 0.0 0.0 0.7 0.0 14.8 2.1 33.4 0.4 0.4 16.9 54.7 0.3 0.3 0.7 0.8 0.5 2.0 0.4 0.1 0.9 0.4 1.3 0.7 0.9 0.2 0.5 177.8 0.5 1.4 1.8 0.2 0.2 1.6 1.1 39.5 1.4 272.2 0.3 124.7 725.8 105.8 1583.4 546.1 1172.3 78.6 664.6 1293.3 409.8 51.0 550.6 1108.0 196.1 1290.7 314.4 823.7 629.9 1421.2 14.0 13.8 13.7 18.5 13.5 17.0 18.3 14.7 17.6 17.1 18.2 22.2 12.3 6.4 43.3 0.0 85.3 28.6 1.3 1.7 2.8 0.4 11.4 12.8 1.2 15.7 7.1 9.2 0.0 3.8 993.2 1.8 0.0 2.8 1.3 4.0 2.5 18.3 0.0 84.2 0.1 1.2 4.7 9.5 14.8 5.5 240.4 0.3 21.0 14.3 571.1 1.7 0.1 0.9 2.0 396.6 584.5 3.0 2.1 392.7 44.4 5.6 309.9 0.7 1687.0 0.0 0.1 1.0 1.4 0.0 97.7 0.6 2.0 6.1 5.1 2.2 19.7 4.2 6.2 2.2 4.9 2.7 21.0 6.0 769.9 1.0 2.7 1.2 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HELB ENSG00000127311 "DNA helicase B" Q8NG08 12 66302493-66343643 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "dendritic cells: 32.8;T-cells: 43.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 2.7;HDLM-2: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052461 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Plasma membrane" "HPA052461: " "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (9.06e-3)" "unprognostic (8.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.00e-1)" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-6)" "unprognostic (3.97e-3)" "unprognostic (9.19e-4)" "unprognostic (1.93e-1)" "unprognostic (9.50e-3)" 0.8 0.3 0.1 0.4 0.1 1.0 0.7 0.1 0.3 0.5 0.2 0.7 0.0 0.4 0.0 0.6 0.5 0.1 0.4 0.1 0.1 0.7 1.2 1.1 0.5 0.4 0.2 0.8 0.9 0.1 1.2 0.0 0.3 0.8 0.1 0.1 0.8 0.0 0.2 0.5 1.2 0.1 0.2 1.8 0.8 0.4 0.3 0.4 0.7 0.0 0.3 0.5 0.6 0.4 0.4 2.7 0.2 0.6 0.1 0.1 0.5 0.6 0.1 0.6 1.2 0.6 1.5 1.0 0.9 0.1 0.9 0.8 0.5 0.2 0.3 2.6 0.2 0.8 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.2 0.1 1.3 0.6 1.1 0.4 1.1 0.0 0.2 0.0 1.1 0.5 0.2 1.0 0.2 0.0 0.0 0.1 0.3 1.7 0.2 0.4 0.4 0.3 1.7 0.2 0.2 0.5 0.3 0.5 1.2 1.0 0.5 0.1 0.9 0.4 4.5 0.8 5.8 2.6 0.5 4.2 0.4 4.9 3.9 1.7 0.7 5.1 4.1 0.7 3.5 0.2 0.6 5.6 1.0 0.1 0.1 0.1 0.3 0.1 0.1 0.4 0.2 0.3 0.2 0.3 0.4 14.7 0.0 7.5 1.3 14.0 0.6 2.5 0.6 10.8 3.2 10.3 9.8 4.0 0.0 6.6 0.0 12.5 3.0 32.8 4.3 1.9 1.7 0.5 12.6 11.5 9.9 4.8 6.1 7.7 1.1 2.5 5.7 11.7 20.9 2.5 10.3 4.6 2.8 3.3 13.5 5.2 5.6 2.0 5.5 3.3 0.8 3.4 10.3 3.6 20.6 8.0 2.4 14.4 0.0 16.2 2.4 3.0 0.7 21.7 5.8 5.9 3.2 3.4 6.5 0.0 11.3 8.0 1.2 1.5 5.2 1.7 2.5 43.5 9.2 6.4 1.8 HELZ "DHRC, HUMORF5, KIAA0054" ENSG00000198265 "Helicase with zinc finger" P42694 17 67070444-67245989 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028276 Approved Approved "Nucleoli,Nucleoli rim,Plasma membrane,Actin filaments" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoli, Nucleoli rim" "Plasma membrane, Actin filaments" "HPA028276: AB_10601814" "unprognostic (3.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.56e-3)" "unprognostic (1.29e-1)" "unprognostic (4.83e-2)" "unprognostic (4.71e-2)" "unprognostic (5.85e-2)" "unprognostic (5.31e-2)" "unprognostic (3.60e-2)" "unprognostic (1.16e-1)" "unprognostic (1.51e-1)" "unprognostic (4.98e-2)" "unprognostic (1.33e-3)" "unprognostic (1.42e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-1)" 6.3 6.6 3.8 8.5 4.9 12.5 6.6 12.0 5.7 7.6 8.4 5.8 4.8 7.4 6.1 4.7 6.1 7.1 6.1 3.6 6.9 6.9 10.9 6.8 9.8 4.1 5.2 12.3 7.8 12.0 6.1 11.2 4.0 6.1 6.6 14.3 6.2 6.2 9.1 4.4 5.9 7.5 3.3 9.1 6.5 10.8 5.5 15.4 8.7 14.0 8.9 6.6 5.0 3.3 10.3 10.0 12.3 12.3 14.8 8.4 18.7 9.0 8.8 11.8 12.4 14.7 7.9 21.2 7.2 12.0 7.4 10.5 23.3 11.3 18.4 8.2 7.3 27.2 10.7 12.5 7.1 22.3 15.6 9.8 10.5 11.4 14.1 8.8 18.1 15.6 19.1 12.9 9.8 13.0 29.0 7.6 7.4 9.2 9.7 19.3 21.6 9.2 9.1 14.3 12.0 11.0 14.3 11.5 15.2 16.9 13.7 13.7 16.1 14.5 16.6 8.0 8.1 10.7 13.4 15.5 7.2 13.7 15.5 2.3 3.3 2.8 5.1 2.8 6.3 1.7 3.1 3.2 2.8 2.8 1.9 2.6 2.3 2.6 1.9 2.2 3.0 2.3 3.8 4.9 12.0 5.7 3.6 6.9 4.1 5.2 4.0 3.3 5.5 3.3 42.9 19.2 37.1 89.1 44.3 32.1 24.6 30.2 29.6 50.8 32.8 23.6 31.1 24.3 30.2 27.6 93.8 32.9 95.8 29.4 7.9 19.1 5.2 49.4 55.8 32.3 38.3 48.8 93.1 14.2 42.8 30.9 38.7 118.5 33.7 51.9 61.8 52.1 31.9 67.3 112.1 30.2 16.2 79.4 28.8 10.5 38.8 55.4 14.2 107.7 62.0 24.0 104.0 134.2 72.6 19.2 23.1 42.9 67.1 29.3 27.7 14.6 26.1 54.9 13.1 45.9 34.0 36.0 26.0 33.6 20.2 18.3 71.0 32.6 26.3 45.8 HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 72.0" "Group enriched" "Detected in many" 4 "NK-cells: 58.7;Spermatocytes: 178.5;Spermatogonia: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 71.4;MOLT-4: 68.2;NB-4: 75.3;U-937: 98.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 19 "cerebellum: 9.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favorable (2.56e-4)" "prognostic favorable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" 5.4 2.9 8.6 8.0 8.9 13.3 8.0 6.8 9.2 8.5 4.9 6.5 5.0 3.9 4.7 2.7 2.3 6.5 1.8 8.9 9.6 3.4 2.0 4.7 13.5 8.0 8.1 5.2 2.1 0.9 5.3 5.6 8.9 3.7 9.5 3.0 3.0 3.4 3.2 3.8 7.6 3.6 7.8 11.1 4.7 72.0 10.6 18.7 2.2 6.2 11.3 6.2 2.0 8.6 16.9 8.5 0.7 0.0 0.7 0.5 0.1 4.0 1.5 9.4 1.5 24.7 26.0 0.0 8.9 7.5 0.0 0.1 0.0 0.2 5.9 5.5 0.0 42.4 31.7 0.0 8.1 25.4 36.4 7.8 0.5 2.1 0.0 0.0 1.9 71.4 0.0 18.5 0.4 42.8 68.2 75.3 24.0 13.5 3.7 29.3 0.0 1.5 0.0 18.0 40.1 0.0 35.3 9.8 0.1 2.4 0.0 55.7 0.5 0.0 31.4 17.5 0.1 11.2 15.0 0.1 0.0 98.6 0.3 43.3 19.7 43.2 61.8 24.0 55.6 12.6 30.0 56.4 24.6 7.1 24.7 45.1 19.6 55.6 29.8 19.5 31.2 39.9 8.6 8.9 6.8 9.2 8.9 9.6 8.0 8.1 8.9 7.8 10.6 8.6 2.4 0.0 1.1 2.3 5.4 1.7 1.4 6.6 1.2 5.2 8.1 7.1 1.8 14.3 4.0 5.5 0.0 12.8 28.0 4.0 3.9 3.0 12.2 2.2 3.6 3.0 4.9 13.9 5.2 1.3 21.5 5.2 2.6 2.4 7.0 2.9 6.1 0.5 15.8 0.0 3.7 4.0 4.1 11.7 3.3 20.1 5.0 7.5 1.8 3.7 11.2 3.6 58.7 4.0 2.7 2.8 7.4 3.0 8.0 1.2 5.5 0.8 2.8 2.4 6.6 3.0 3.5 178.5 107.7 2.9 1.6 5.2 23.0 8.5 6.1 3.3 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "CAB017188: , HPA048389: AB_2680382, HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favorable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 5.3 5.7 2.5 2.3 2.9 4.0 4.9 1.5 3.1 5.5 3.0 9.3 2.6 7.6 1.7 5.2 6.1 2.2 7.4 2.3 1.1 3.7 3.7 5.1 2.3 2.0 1.8 8.3 6.1 5.4 6.3 2.7 2.7 4.4 2.8 5.3 4.8 2.9 14.2 5.3 6.1 3.7 0.4 4.3 6.3 4.8 2.7 4.4 5.8 9.3 2.4 5.6 5.0 6.2 8.5 16.5 11.2 4.7 9.2 6.9 3.2 6.0 7.1 7.6 7.3 8.6 1.1 8.5 7.2 10.4 11.5 8.5 12.0 5.9 5.6 5.2 7.8 54.0 20.2 2.9 3.5 12.8 4.1 5.7 4.5 9.0 11.2 4.9 10.2 7.0 21.2 3.4 7.3 3.9 2.9 4.3 3.4 6.4 7.1 10.2 16.0 0.7 2.6 18.2 12.3 7.1 14.6 4.1 4.5 5.8 4.8 14.8 15.3 14.0 9.2 5.5 9.1 2.2 3.3 7.7 6.5 5.9 7.6 0.1 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.6 0.2 0.1 2.5 2.9 1.5 3.1 2.3 1.1 2.0 1.8 2.7 0.4 2.7 6.2 56.2 22.4 23.5 68.9 34.3 16.4 15.3 18.1 27.9 107.9 39.1 31.2 66.6 21.5 23.6 64.4 148.0 25.9 28.5 31.8 1.9 28.7 13.0 35.0 55.8 73.3 28.1 67.9 88.9 30.4 15.5 34.3 43.3 29.6 3.8 135.0 38.9 36.7 19.0 122.8 82.9 32.1 16.2 22.3 20.7 15.8 56.2 22.1 69.4 84.3 26.9 41.0 45.3 65.9 89.7 36.6 30.8 52.3 56.6 20.5 31.1 19.8 19.6 142.9 65.7 46.0 43.2 72.5 66.4 38.3 21.0 17.8 30.0 62.7 35.5 11.5 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 39.2;T-47d: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" 9.6 7.9 1.3 5.3 2.1 0.6 7.8 1.4 1.9 6.7 9.3 5.8 5.9 4.9 12.4 4.8 4.5 8.1 3.7 1.5 1.5 6.7 15.4 7.5 3.6 2.4 1.7 7.3 6.3 15.4 1.2 6.1 2.2 6.8 6.9 1.3 6.9 9.6 2.3 2.8 5.0 6.0 1.7 8.6 8.3 1.7 1.9 1.7 9.9 3.0 3.1 7.4 3.2 2.8 17.2 39.2 0.7 18.6 27.3 21.1 0.1 12.2 28.5 15.1 23.6 3.3 34.3 1.8 32.4 20.2 22.9 10.7 0.0 14.2 19.1 4.6 0.2 0.5 8.1 2.6 5.6 0.0 0.7 21.6 4.0 16.7 1.4 13.2 10.4 0.0 0.7 0.4 13.0 7.2 0.1 0.2 0.9 8.1 0.0 2.3 0.0 0.3 12.5 11.5 0.1 0.1 7.3 0.0 10.2 0.3 54.0 1.9 8.2 10.6 1.1 10.7 10.6 0.2 0.4 0.2 15.9 0.2 23.5 1.3 10.7 0.0 1.5 10.4 1.2 3.3 1.6 2.1 4.7 1.3 0.4 1.0 1.9 0.2 9.2 0.3 0.3 3.8 1.3 2.1 1.4 1.9 1.5 1.5 2.4 1.7 2.2 1.7 1.9 2.8 3.9 3.2 5.1 1.0 1.7 1.7 2.6 3.7 6.2 1.0 3.7 2.2 3.2 2.8 6.7 5.5 2.1 1.7 0.5 3.8 0.0 4.1 0.1 1.8 2.3 3.4 1.8 2.7 0.1 3.4 0.8 4.6 8.2 1.5 2.5 3.0 6.8 12.2 11.1 0.0 0.1 4.0 4.1 25.4 7.6 0.2 3.7 7.4 0.0 2.8 3.8 2.9 2.1 0.0 3.3 2.4 0.9 6.0 0.3 2.6 2.9 2.7 5.9 1.7 0.0 5.7 2.4 0.2 1.1 3.4 3.4 1.8 1.0 2.8 3.3 1.9 HIF3A "bHLHe17, IPAS, MOP7, PASD7" ENSG00000124440 "Hypoxia inducible factor 3 subunit alpha" Q9Y2N7 19 46297042-46343433 "Predicted intracellular proteins, Transcription factors" "Angiogenesis, Apoptosis, Stress response, Transcription, Transcription regulation" "Developmental protein, Repressor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 83.5;Astrocytes: 257.9;Endothelial cells: 60.4;Leydig cells: 136.4;Muller glia cells: 79.9;Oligodendrocyte precursor cells: 69.9;Peritubular cells: 103.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.3;HHSteC: 19.1;HSkMC: 16.8;TIME: 16.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041141 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041141: AB_10803997" "unprognostic (9.20e-2)" "unprognostic (2.99e-1)" "unprognostic (5.48e-2)" "prognostic unfavorable (6.90e-9)" "unprognostic (4.12e-2)" "unprognostic (2.35e-2)" "unprognostic (3.57e-3)" "unprognostic (1.30e-1)" "unprognostic (3.32e-2)" "unprognostic (1.38e-2)" "unprognostic (3.76e-2)" "unprognostic (7.07e-2)" "unprognostic (3.41e-4)" "unprognostic (1.55e-2)" "unprognostic (1.61e-1)" "unprognostic (4.45e-4)" "unprognostic (5.98e-2)" 34.2 8.8 24.1 1.1 24.7 0.7 24.2 17.5 25.9 32.5 9.4 55.4 1.1 31.1 4.1 10.8 35.8 2.6 55.9 19.5 17.4 7.3 2.7 32.8 1.2 22.2 22.3 34.2 6.5 0.5 22.6 27.4 18.6 22.3 2.0 10.0 7.5 7.1 10.7 10.8 24.8 3.0 16.8 31.8 37.3 5.4 22.5 0.5 13.0 9.7 0.4 55.0 25.1 17.3 0.0 0.0 1.5 0.2 4.3 9.3 0.4 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 19.1 0.1 0.5 16.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 2.3 0.0 0.1 16.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.7 0.0 0.0 1.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.1 0.7 0.1 0.4 0.7 0.1 0.0 24.1 24.7 17.5 25.9 19.5 17.4 22.2 22.3 18.6 16.8 22.5 17.3 83.5 3.2 1.8 257.9 0.5 1.1 2.2 0.3 0.6 1.5 1.4 0.9 45.7 17.2 0.7 0.0 0.0 0.2 0.3 0.2 1.9 0.0 1.9 2.4 7.0 60.4 1.2 8.0 0.7 0.0 0.4 13.6 1.1 2.3 0.0 3.1 51.0 0.9 0.6 0.0 3.5 1.2 0.0 1.3 2.1 7.4 136.4 0.7 3.6 33.7 0.0 79.9 0.0 69.9 1.2 0.1 8.0 103.4 0.0 1.6 0.5 0.1 0.0 2.5 6.6 5.5 8.4 1.6 3.6 0.2 2.3 0.5 0.4 0.1 2.1 0.7 HINT1 "HINT, PKCI-1, PRKCNH1" ENSG00000169567 "Histidine triad nucleotide binding protein 1" P49773 5 131155383-131224468 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 3537.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044577 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 2800000 "Cluster 30: Non-specific - Translation" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 32: Non-specific - Translation" Cytosol "Nucleoplasm, Plasma membrane" "HPA044577: AB_10795618" "unprognostic (2.00e-1)" "unprognostic (9.27e-2)" "unprognostic (2.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.19e-1)" "unprognostic (1.35e-1)" "unprognostic (8.30e-3)" "unprognostic (2.48e-1)" "unprognostic (1.30e-2)" "unprognostic (6.49e-2)" "unprognostic (6.50e-3)" "unprognostic (4.43e-2)" "unprognostic (4.39e-3)" "unprognostic (2.08e-1)" "unprognostic (1.74e-1)" "unprognostic (1.67e-1)" "unprognostic (3.68e-1)" 132.6 175.0 235.7 139.8 245.1 259.3 172.7 241.6 326.2 117.6 243.8 227.6 176.1 119.6 187.5 181.3 165.6 108.0 167.2 245.9 247.8 256.7 474.2 119.0 206.5 241.6 237.2 121.5 165.5 285.6 152.5 87.5 249.1 155.1 226.5 110.8 172.8 116.4 334.1 170.0 196.3 124.2 242.6 126.9 136.5 80.1 240.8 166.5 177.2 278.4 192.3 152.9 129.7 245.3 437.1 522.7 448.2 877.2 273.1 297.1 441.3 300.3 230.9 235.4 272.1 547.1 516.8 563.3 625.7 329.6 569.1 253.4 315.4 635.3 244.1 500.0 514.6 199.1 814.0 771.9 532.6 349.4 65.4 400.1 618.6 295.8 528.2 533.7 314.1 727.8 313.4 1132.1 338.8 419.9 548.0 945.6 415.6 425.6 362.0 407.9 436.1 988.1 500.6 567.0 563.3 351.9 380.5 243.5 612.0 574.4 291.2 520.8 396.0 351.7 244.0 323.0 684.2 342.3 561.4 578.8 497.8 586.8 346.3 179.8 187.9 85.0 196.3 109.9 298.0 384.9 462.0 294.2 396.9 332.6 416.0 325.5 35.6 269.0 128.0 521.4 362.5 608.6 235.7 245.1 241.6 326.2 245.9 247.8 241.6 237.2 249.1 242.6 240.8 245.3 582.7 282.0 279.1 34.3 718.2 1301.2 1472.2 1928.1 889.5 191.2 1134.3 1831.1 517.0 1028.0 882.2 715.4 45.9 780.9 641.6 1245.1 1663.0 1024.5 783.0 718.9 443.7 501.2 698.1 669.7 53.8 774.3 1632.8 400.2 355.2 753.7 108.2 666.5 436.2 2380.1 887.1 148.0 48.0 947.2 915.5 472.4 906.9 206.3 392.4 447.0 965.8 34.7 1269.4 405.1 488.1 26.7 55.4 894.3 1094.2 418.6 679.7 1998.9 1690.3 3537.5 708.3 194.0 243.3 287.0 730.3 625.5 197.9 1109.1 1146.1 456.8 671.1 464.3 1280.4 1713.2 HIP1R "FLJ14000, HIP12, HIP3, ILWEQ, KIAA0655" ENSG00000130787 "Huntingtin interacting protein 1 related" O75146 12 122834453-122862961 "Cancer-related genes, Predicted intracellular proteins" Endocytosis Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 103.4" "Cell type enhanced" "Detected in many" "Astrocytes: 134.5;Oligodendrocyte precursor cells: 168.9;Oligodendrocytes: 117.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 9.3;naive B-cell: 10.6" "Group enriched" "Detected in many" 8 "B-cells: 10.6;granulocytes: 2.9;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017187, HPA038135, HPA038136" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" Vesicles "CAB017187: , HPA038135: AB_2675851, HPA038136: AB_2675852" "unprognostic (4.52e-1)" "unprognostic (6.39e-2)" "unprognostic (7.07e-2)" "unprognostic (6.55e-3)" "unprognostic (8.67e-2)" "unprognostic (1.00e-2)" "unprognostic (1.02e-2)" "unprognostic (8.11e-2)" "unprognostic (6.37e-2)" "unprognostic (1.76e-1)" "unprognostic (1.39e-2)" "unprognostic (6.72e-2)" "prognostic favorable (6.50e-7)" "unprognostic (2.18e-2)" "unprognostic (2.84e-1)" "unprognostic (2.54e-3)" "prognostic favorable (7.26e-4)" 18.5 24.0 68.6 10.4 95.5 13.3 22.6 78.8 80.3 16.0 33.5 16.3 31.8 9.0 3.8 18.0 9.0 7.7 18.9 68.0 67.8 50.2 25.6 15.4 17.5 87.3 83.8 5.6 50.2 8.9 42.0 4.7 75.6 21.0 4.9 5.5 58.7 10.5 7.2 51.7 36.0 2.2 65.3 20.9 66.7 8.5 85.7 12.6 21.5 4.4 11.7 11.4 19.7 103.4 38.1 10.8 8.0 33.1 2.3 6.1 39.2 5.9 9.5 5.9 4.6 16.8 11.1 36.0 19.0 4.3 8.9 32.4 9.7 21.4 0.5 5.8 14.0 0.8 13.8 17.8 7.1 2.8 24.5 3.8 14.9 8.0 13.4 8.1 40.5 16.5 9.6 2.0 3.4 54.4 17.4 8.8 7.4 32.8 12.8 9.0 10.2 12.5 19.6 45.4 8.1 17.9 7.1 18.0 9.5 4.3 36.6 1.5 32.8 3.7 27.5 11.7 5.7 24.8 14.2 21.8 6.0 6.0 3.1 0.0 0.0 2.9 2.7 0.0 1.5 9.3 1.7 2.1 0.0 10.6 3.0 1.9 0.2 0.7 0.0 0.0 0.4 2.0 68.6 95.5 78.8 80.3 68.0 67.8 87.3 83.8 75.6 65.3 85.7 103.4 57.0 0.0 13.4 134.5 38.0 13.3 16.8 8.4 6.8 16.4 21.2 18.2 4.2 60.1 11.1 60.7 29.2 3.7 18.2 28.4 0.0 40.1 3.1 21.9 4.7 18.2 7.8 1.3 11.2 28.7 13.1 2.3 80.5 37.5 5.7 25.3 19.2 24.4 0.6 18.5 9.7 29.9 22.4 1.2 4.2 2.9 1.5 2.2 10.6 9.4 0.1 12.5 7.2 168.9 117.8 22.7 25.3 1.2 17.2 20.2 47.5 17.9 14.2 16.6 0.0 2.5 4.1 6.5 13.3 11.5 21.0 1.9 15.0 1.3 23.9 28.4 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HLA-DPB1 HLA-DP1B ENSG00000223865 "Major histocompatibility complex, class II, DP beta 1" P04440 6 33075990-33089696 "Human disease related genes, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 278.7;lymphoid tissue: 409.4" "Cell type enhanced" "Detected in many" "B-cells: 1569.6;Kupffer cells: 2374.2;Langerhans cells: 12627.8;Macrophages: 2453.8;monocytes: 3754.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "myeloid DC: 285.5" "Group enriched" "Detected in all" 10 "B-cells: 227.8;dendritic cells: 285.5;monocytes: 137.5" "Group enriched" "Detected in some" 6 "HDLM-2: 65.9;REH: 26.5" "HPA011078, HPA058509" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA 470000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 64: Macrophages - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions" Nucleoplasm "HPA011078: AB_1079378, HPA058509: AB_2683737" "unprognostic (5.44e-3)" "unprognostic (7.03e-3)" "unprognostic (9.84e-2)" "prognostic favorable (3.38e-4)" "unprognostic (9.43e-2)" "unprognostic (1.80e-2)" "unprognostic (1.52e-1)" "unprognostic (1.51e-3)" "unprognostic (1.77e-2)" "unprognostic (5.64e-2)" "unprognostic (1.57e-1)" "unprognostic (4.34e-1)" "unprognostic (4.35e-2)" "unprognostic (1.80e-1)" "unprognostic (4.17e-2)" "unprognostic (3.58e-2)" "unprognostic (1.85e-1)" 151.6 101.3 1.0 42.0 1.0 5.8 112.8 3.3 1.3 68.2 0.9 69.4 12.4 50.2 2.9 43.9 55.7 17.2 51.1 0.8 1.8 96.1 38.6 278.7 66.7 1.8 1.3 26.2 32.4 1.0 51.5 0.8 1.8 70.3 2.5 1.5 57.2 6.4 25.1 72.3 176.5 4.7 2.1 409.4 54.1 12.8 1.0 10.9 69.5 1.3 42.2 49.2 56.5 3.0 0.0 0.0 0.1 0.0 0.0 0.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 1.3 6.2 0.2 0.0 0.1 0.0 0.0 0.0 65.9 1.9 1.5 0.0 0.0 0.0 0.0 0.5 1.4 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.9 0.0 0.0 26.5 0.1 0.3 0.3 0.0 0.9 0.0 0.0 0.3 0.1 0.4 0.0 0.1 1.8 0.1 0.2 0.0 0.0 7.2 0.3 4.4 1.1 0.0 0.0 0.5 59.6 4.0 14.8 137.5 1.8 226.6 5.1 22.2 285.5 227.8 2.3 11.9 1.6 8.2 60.3 77.5 22.7 107.8 1.0 1.0 3.3 1.3 0.8 1.8 1.8 1.3 1.8 2.1 1.0 3.0 354.8 67.3 330.7 1.3 1569.6 300.5 26.0 5.6 19.4 26.9 54.0 123.6 10.3 67.2 62.3 29.5 16.7 4.8 692.9 7.8 3.9 58.3 3.6 2.0 16.3 297.8 9.6 87.9 1.3 15.6 8.1 62.3 48.4 2.7 61.6 13.6 97.1 8.8 1099.4 8.4 1.6 13.0 10.2 2374.2 12627.8 10.1 27.4 2453.8 323.7 20.6 3754.7 43.3 203.9 2.5 0.2 7.4 10.0 21.1 50.9 28.2 154.7 60.2 54.4 21.9 46.0 21.4 47.5 1.3 7.8 6.4 233.3 9.0 200.7 3.9 23.0 51.7 HMGCS1 HMGCS ENSG00000112972 "3-hydroxy-3-methylglutaryl-CoA synthase 1" Q01581 5 43287470-43313512 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 390.2" "Cell type enhanced" "Detected in many" "Hepatocytes: 511.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "AF22: 797.7;GAMG: 523.5;HBEC3-KT: 467.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032907, HPA036913, HPA036914" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No 470000 "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB032907: AB_2118319, HPA036913: AB_2675380, HPA036914: AB_10671751" "unprognostic (1.31e-1)" "unprognostic (5.12e-3)" "unprognostic (6.82e-3)" "unprognostic (4.59e-2)" "unprognostic (8.39e-2)" "unprognostic (2.49e-2)" "unprognostic (1.03e-1)" "unprognostic (3.14e-2)" "unprognostic (1.27e-2)" "unprognostic (3.13e-1)" "unprognostic (6.40e-3)" "unprognostic (9.15e-2)" "prognostic favorable (3.87e-6)" "unprognostic (1.09e-1)" "unprognostic (9.22e-2)" "unprognostic (3.03e-2)" "unprognostic (2.37e-2)" 19.2 55.2 25.2 27.2 32.9 15.8 40.1 23.0 38.6 56.4 16.8 50.2 93.6 19.8 36.1 137.5 12.4 23.3 16.1 36.1 44.6 32.8 390.2 51.4 21.5 46.5 34.7 21.6 26.6 31.7 15.0 22.5 47.2 40.5 45.4 34.2 53.2 15.7 17.8 85.9 47.2 19.9 24.7 14.8 43.4 33.2 35.3 19.1 23.6 16.7 31.5 18.3 69.5 30.4 103.4 48.8 797.7 93.0 45.8 178.4 54.1 16.2 63.8 22.8 45.2 86.6 146.6 108.4 35.6 23.3 523.5 80.2 199.7 467.2 24.1 23.5 240.7 40.1 45.3 119.3 71.3 88.0 28.0 98.5 56.2 119.5 47.9 14.0 23.7 98.4 73.1 291.7 19.4 48.9 81.3 111.9 143.1 41.7 25.9 57.5 111.9 121.8 357.7 158.2 68.2 33.0 83.6 41.4 25.9 114.5 63.6 116.7 28.3 17.1 85.7 18.0 15.5 38.8 64.0 148.3 15.0 106.2 15.5 3.3 1.8 1.9 2.4 3.3 2.4 3.8 2.6 3.4 3.5 2.9 2.2 3.1 3.0 3.2 3.6 2.9 2.6 1.6 25.2 32.9 23.0 38.6 36.1 44.6 46.5 34.7 47.2 24.7 35.3 30.4 27.8 67.3 172.6 70.5 44.8 108.3 42.3 93.8 68.3 43.6 46.3 30.0 8.9 47.1 79.2 47.8 52.1 22.3 43.3 211.2 13.7 43.0 9.0 47.1 20.2 31.3 92.1 22.3 44.9 59.8 41.1 32.3 100.4 98.6 58.5 56.6 22.1 511.7 25.5 48.8 42.6 101.9 75.3 21.9 38.2 3.2 12.8 27.5 26.6 15.0 49.1 26.4 14.4 53.3 41.8 50.4 132.3 14.3 38.1 149.2 56.8 21.4 51.1 50.1 0.0 40.1 32.8 20.0 8.7 197.9 236.4 44.5 36.4 129.4 62.9 74.5 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HOMER3 HOMER-3 ENSG00000051128 "Homer scaffold protein 3" Q9NSC5 19 18929201-18941261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 125.1" "Cell type enhanced" "Detected in many" "Hofbauer cells: 76.4;Muller glia cells: 72.6;Proximal tubular cells: 84.2;Theca cells: 322.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 15.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "NB-4: 353.6;THP-1: 420.0;U-266/84: 375.4" "Region enriched" "Detected in all" 6 "cerebellum: 189.2" "Low region specificity" "Detected in all" "CAB032656, HPA040999, CAB079015" Enhanced Supported Supported "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane, Cytoplasmic bodies" "CAB032656: AB_2120801, CAB079015: , HPA040999: AB_2677242" "unprognostic (3.41e-2)" "unprognostic (1.71e-1)" "prognostic unfavorable (4.24e-5)" "unprognostic (1.19e-1)" "unprognostic (2.06e-1)" "unprognostic (1.11e-1)" "prognostic unfavorable (4.93e-5)" "unprognostic (1.07e-1)" "unprognostic (8.88e-2)" "unprognostic (5.78e-2)" "unprognostic (1.28e-1)" "unprognostic (2.10e-2)" "unprognostic (5.99e-2)" "unprognostic (3.76e-2)" "unprognostic (2.33e-1)" "unprognostic (1.41e-1)" "unprognostic (4.11e-2)" 33.1 29.6 33.3 9.9 41.9 22.3 26.2 76.9 44.6 31.7 41.1 27.0 7.0 24.6 6.4 15.3 16.7 16.5 25.0 40.4 35.1 52.2 6.1 25.6 7.9 42.3 40.9 20.1 12.4 37.5 8.6 14.7 42.8 21.9 6.0 5.9 27.6 9.4 114.5 35.4 14.4 10.6 39.4 125.1 17.0 9.2 41.6 7.4 49.3 18.6 3.8 29.7 26.0 45.5 112.1 28.5 53.1 44.4 48.3 48.6 26.2 108.1 94.9 106.4 53.4 14.6 41.8 0.9 49.9 122.1 76.1 68.6 18.4 140.4 58.9 4.0 11.0 0.1 9.7 27.5 44.9 21.5 1.7 39.3 89.4 59.0 79.1 113.0 130.3 7.9 3.2 28.6 78.1 30.3 1.9 353.6 27.3 6.1 115.5 55.2 16.2 53.4 38.2 28.3 0.2 44.8 26.6 31.2 78.5 10.2 14.0 420.0 105.3 94.0 42.0 114.5 132.2 274.2 375.4 93.6 148.0 270.6 69.8 0.1 15.0 2.9 0.1 5.3 0.0 2.3 0.8 0.3 1.3 2.7 0.1 0.0 5.8 0.0 1.6 0.2 0.8 4.2 33.3 41.9 76.9 44.6 40.4 35.1 42.3 40.9 42.8 39.4 41.6 45.5 21.7 3.2 0.0 9.4 9.3 11.9 22.4 24.4 6.8 2.2 14.3 22.5 4.1 2.8 8.0 12.9 0.0 1.0 0.6 0.1 11.7 22.9 2.0 4.3 18.7 38.0 1.8 0.4 0.3 13.6 2.4 20.5 0.0 6.3 10.2 34.8 21.8 0.7 76.4 1.7 3.9 0.9 22.4 16.2 7.6 1.7 13.7 32.2 12.4 1.9 8.3 72.6 0.0 1.0 13.4 42.0 0.0 10.9 13.8 25.2 0.0 84.2 3.6 4.1 0.0 14.4 27.8 4.7 6.7 4.2 14.5 1.1 2.5 322.4 0.3 21.4 HOXC5 "HOX3, HOX3D" ENSG00000172789 "Homeobox C5" Q00444 12 54033050-54035361 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.6;fallopian tube: 4.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 5.2;Fibroblasts: 2.6;Granulosa cells: 2.5;Leydig cells: 2.5;Peritubular cells: 2.6;Skeletal myocytes: 2.6;Smooth muscle cells: 2.5;Spermatocytes: 3.2;Squamous epithelial cells: 2.2" "Cancer enhanced" "Detected in single" "ovarian cancer: 0.7" "Group enriched" "Detected in many" 15 "medulla oblongata: 3.4;pons: 3.6;spinal cord: 1.9;white matter: 1.2" "Immune cell enhanced" "Detected in single" "gdT-cell: 3.0" "Lineage enriched" "Detected in single" 31 "T-cells: 3.0" "Cell line enhanced" "Detected in some" "AN3-CA: 7.1;ASC TERT1: 4.8;HSkMC: 4.5;SH-SY5Y: 7.6" "Region enriched" "Detected in single" 46 "pons and medulla: 4.6" "Group enriched" "Detected in some" 5 "medulla oblongata: 1.5;spinal cord: 2.1" HPA026794 Uncertain Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Cell Junctions" "HPA026794: AB_10612118" "unprognostic (1.57e-1)" "unprognostic (7.73e-3)" "unprognostic (1.70e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-3)" "unprognostic (2.87e-3)" "unprognostic (6.89e-2)" "unprognostic (9.53e-3)" "unprognostic (1.86e-2)" "unprognostic (2.69e-2)" "unprognostic (2.01e-3)" "unprognostic (1.17e-2)" "unprognostic (7.53e-3)" "unprognostic (2.19e-3)" "unprognostic (1.08e-2)" 1.0 0.9 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 2.7 0.9 4.1 0.1 0.0 0.0 0.0 0.9 0.0 0.1 0.2 3.4 0.1 2.6 0.0 0.0 0.0 0.8 3.6 0.0 0.0 0.0 0.0 0.2 1.2 1.1 0.7 1.5 1.9 0.0 2.1 1.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.8 1.9 0.0 7.1 4.0 4.8 0.0 0.4 0.3 0.8 0.6 3.0 0.4 0.0 0.5 2.1 0.0 1.1 0.1 0.0 0.3 2.4 2.4 0.0 1.0 0.1 0.1 0.0 0.1 4.5 0.4 3.3 0.4 0.0 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.0 1.0 0.0 0.0 7.6 0.5 0.2 3.9 0.9 1.4 0.0 0.0 1.2 0.7 2.6 0.2 0.0 0.0 0.0 0.1 0.1 2.8 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 3.6 1.9 0.0 1.2 0.5 0.0 0.0 0.0 0.0 0.9 0.0 0.0 5.2 0.0 0.3 0.9 0.1 0.0 0.0 1.8 0.0 0.1 0.8 0.0 1.9 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 2.6 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.5 0.0 0.0 0.0 2.6 2.5 3.2 1.0 2.2 0.9 0.3 0.1 1.0 0.1 0.0 HOXD4 "HOX4, HOX4B" ENSG00000170166 "Homeobox D4" P09016 2 176151550-176153226 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 24.4;epididymis: 28.0" "Cell type enhanced" "Detected in some" "Adipocytes: 5.5;Collecting duct cells: 16.5;Early spermatids: 3.7;Endothelial cells: 3.6;Leydig cells: 4.7;Proximal tubular cells: 6.5;Sertoli cells: 6.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 5.3" "Group enriched" "Detected in many" 21 "medulla oblongata: 10.6;pons: 5.6;spinal cord: 8.1;white matter: 7.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 16.6;HEK 293: 39.7;RPTEC TERT1: 29.6;SK-MEL-30: 11.0" "Region enriched" "Detected in single" 46 "pons and medulla: 4.5" "Group enriched" "Detected in some" 4 "medulla oblongata: 6.0;spinal cord: 7.8" "HPA054383, HPA070349" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA054383: AB_2682470, HPA070349: AB_2686258" "unprognostic (9.37e-2)" "unprognostic (1.54e-1)" "unprognostic (1.03e-3)" "unprognostic (1.10e-3)" "unprognostic (9.21e-2)" "unprognostic (5.17e-3)" "unprognostic (5.19e-2)" "unprognostic (6.69e-3)" "unprognostic (1.66e-1)" "unprognostic (3.47e-1)" "unprognostic (1.49e-1)" "unprognostic (2.50e-1)" "unprognostic (7.78e-2)" "unprognostic (1.12e-2)" "unprognostic (9.93e-2)" "unprognostic (5.81e-2)" "unprognostic (1.61e-1)" 6.9 8.3 0.0 1.6 0.0 0.0 7.4 0.0 0.1 7.1 0.0 7.3 1.0 24.4 28.0 1.1 14.3 1.5 0.6 0.0 0.0 18.5 0.0 0.4 1.7 10.6 0.3 15.1 0.6 0.1 0.0 0.4 5.6 2.9 2.0 0.0 0.7 11.1 2.8 2.4 6.2 9.7 8.1 7.2 1.0 3.0 0.0 0.2 1.2 0.5 0.4 2.7 4.0 7.3 0.5 0.3 0.0 0.0 2.0 3.0 0.0 0.2 0.9 0.1 1.1 0.9 0.0 0.0 16.6 3.4 0.7 0.2 2.6 0.0 0.4 0.0 39.7 0.5 0.0 0.0 0.5 0.0 0.1 9.3 2.6 0.0 0.5 0.2 6.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 29.6 4.1 2.5 4.2 0.6 0.0 11.0 0.6 0.0 0.0 5.0 0.5 0.2 2.9 2.1 0.0 0.1 0.0 2.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.6 0.3 5.6 8.1 0.0 7.3 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 16.5 0.0 0.0 0.0 0.9 0.0 0.0 3.7 0.1 1.1 3.6 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.7 2.6 4.7 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 3.0 0.0 0.1 0.3 6.5 0.0 0.0 6.6 0.6 0.9 0.3 0.4 0.0 0.6 0.0 0.1 3.0 1.3 0.0 HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" "HPA046281: AB_10961641, HPA052778: AB_2681943" "unprognostic (1.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.04e-4)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" 7.6 9.2 4.2 11.4 4.7 5.6 7.9 4.8 4.2 7.5 8.3 7.5 11.0 9.9 4.9 5.6 8.6 9.0 5.0 3.7 6.0 12.0 8.0 9.7 17.6 6.7 5.6 14.0 6.7 5.7 3.7 10.6 6.8 9.3 9.1 9.6 6.6 8.5 2.8 4.7 10.8 10.3 5.6 16.0 9.2 6.9 5.2 16.8 8.8 3.9 16.4 8.4 5.2 8.5 49.1 26.5 15.7 16.3 21.4 27.4 11.7 19.7 38.4 25.3 32.4 9.1 31.8 12.4 23.8 23.7 115.3 16.5 17.4 13.4 32.4 30.6 13.9 5.8 11.8 9.9 19.1 15.7 9.1 18.0 13.5 24.4 10.0 51.6 26.2 20.2 6.5 29.4 32.5 30.3 11.3 22.1 37.7 26.3 21.1 13.4 10.3 33.7 13.9 24.1 4.7 12.4 16.8 17.7 35.9 33.4 19.2 20.5 13.2 25.2 4.5 26.0 29.0 24.0 10.0 30.6 37.7 30.1 6.3 20.7 12.5 12.1 12.0 15.2 14.5 15.4 10.9 12.9 19.5 12.2 8.4 10.9 5.7 9.8 10.3 11.0 10.7 10.9 4.2 4.7 4.8 4.2 3.7 6.0 6.7 5.6 6.8 5.6 5.2 8.5 9.9 12.8 19.5 17.6 28.6 3.7 3.9 11.5 6.8 6.7 9.1 7.4 2.5 5.7 22.9 7.3 2.1 21.0 24.3 8.0 5.9 10.7 3.0 10.6 11.6 9.9 9.0 7.4 13.3 18.1 14.6 10.8 16.8 10.4 15.2 18.0 17.5 6.9 19.8 3.3 16.5 8.8 14.2 29.3 23.8 4.8 11.5 33.1 14.2 38.4 14.4 25.1 19.6 19.1 27.3 12.9 4.9 30.1 15.4 6.8 13.6 22.8 20.7 5.2 0.0 7.4 8.4 4.4 8.4 8.7 5.3 14.1 18.9 5.4 7.5 5.1 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 HS6ST3 ENSG00000185352 "Heparan sulfate 6-O-sulfotransferase 3" Q8IZP7 13 96090107-96839562 "Metabolic proteins, Predicted intracellular proteins" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.5" "Group enriched" "Detected in some" 27 "Excitatory neurons: 1308.8;Inhibitory neurons: 893.1;Oligodendrocyte precursor cells: 968.6" "Cancer enhanced" "Detected in many" "breast cancer: 1.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "RT4: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA078257 Approved "Nucleoplasm,Nuclear membrane,Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA 24000 "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nuclear membrane" "Plasma membrane, Actin filaments" "HPA078257: AB_2732374" "unprognostic (2.34e-2)" "unprognostic (1.90e-2)" "unprognostic (2.82e-2)" "unprognostic (1.72e-2)" "unprognostic (4.88e-2)" "unprognostic (2.78e-2)" "unprognostic (1.55e-1)" "unprognostic (3.67e-3)" "unprognostic (8.11e-3)" "unprognostic (1.19e-1)" "prognostic favorable (6.12e-5)" "unprognostic (1.54e-4)" "unprognostic (2.24e-1)" "unprognostic (1.57e-3)" "unprognostic (9.89e-2)" 1.4 4.2 1.4 0.2 3.5 0.0 0.3 0.0 9.0 1.8 0.0 0.2 0.4 2.1 2.1 0.4 0.5 0.2 0.9 12.5 7.3 0.8 0.0 0.0 0.0 0.1 5.2 0.1 2.2 2.1 1.9 0.0 0.3 0.2 0.1 2.2 0.0 0.2 1.1 0.5 0.4 1.5 0.3 0.0 0.9 0.3 6.1 0.0 2.4 0.0 0.0 2.7 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.1 0.0 0.0 1.1 0.0 1.2 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 17.3 0.9 0.7 0.1 0.1 0.0 0.2 0.5 0.0 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 3.5 0.0 9.0 12.5 7.3 0.1 5.2 0.3 0.3 6.1 0.0 0.0 0.0 0.0 33.6 0.0 0.0 0.0 0.0 0.0 3.9 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.3 0.6 0.1 0.0 0.0 1308.8 0.6 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.0 0.0 3.3 893.1 0.0 0.0 0.0 0.0 1.0 0.6 0.0 0.0 38.4 0.0 0.9 0.0 968.6 16.5 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 2.2 0.0 0.1 1.8 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 HSFX1 LW-1 ENSG00000171116 "Heat shock transcription factor family, X-linked 1" Q9UBD0 X 149774068-149776867 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "HPA051700, HPA063040" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: AB_2681578, HPA063040: AB_2732695" "unprognostic (3.50e-2)" "unprognostic (2.86e-1)" "unprognostic (2.30e-2)" "unprognostic (6.32e-2)" "unprognostic (3.38e-2)" "unprognostic (3.78e-1)" "unprognostic (5.03e-2)" "unprognostic (3.70e-1)" "unprognostic (3.56e-1)" "unprognostic (1.47e-1)" "unprognostic (1.68e-2)" "unprognostic (1.92e-1)" "unprognostic (2.46e-1)" "unprognostic (3.10e-1)" 0.8 0.8 1.5 0.3 1.8 0.0 1.1 1.9 2.6 1.7 2.8 1.8 0.5 1.3 3.3 1.2 1.5 0.8 1.9 2.0 1.4 1.0 1.0 0.9 0.4 1.5 1.5 3.1 1.0 0.8 1.2 1.2 2.2 2.0 0.1 0.7 1.3 0.6 1.3 1.2 1.0 0.4 1.0 2.5 1.0 3.4 1.8 0.1 1.5 0.0 0.4 1.4 1.5 1.8 0.0 1.1 0.0 0.4 1.4 0.9 0.2 0.2 0.0 0.2 0.0 0.8 0.7 0.7 1.2 0.1 0.7 0.0 0.6 0.2 0.1 0.1 0.0 0.2 0.5 0.1 0.8 0.1 0.1 0.0 0.0 0.0 0.6 1.1 0.3 0.0 0.0 0.2 0.1 1.3 0.1 0.5 0.3 0.1 0.6 0.3 0.8 0.0 1.0 0.5 0.5 0.2 0.1 0.0 0.2 0.8 0.1 0.2 0.2 0.0 0.6 0.2 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.5 1.8 1.9 2.6 2.0 1.4 1.5 1.5 2.2 1.0 1.8 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSFX2 ENSG00000268738 "Heat shock transcription factor family, X-linked 2" Q9UBD0 X 149592512-149595314 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 12.3" "Cell type enriched" "Detected in single" 16 "Cardiomyocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.1;HEK 293: 1.1;hTCEpi: 1.5;MCF7: 1.4;U-138 MG: 1.5" "HPA051700, HPA063040" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA051700: AB_2681578, HPA063040: AB_2732695" "unprognostic (7.64e-2)" "unprognostic (6.92e-3)" "unprognostic (2.00e-1)" 0.3 0.4 0.8 0.2 1.0 0.0 0.6 0.9 2.2 0.5 1.0 0.6 0.5 0.6 0.2 0.4 1.0 0.0 1.2 0.7 0.1 0.5 0.5 0.6 0.1 0.5 0.3 1.0 0.4 1.3 0.4 0.4 0.4 0.9 0.5 1.0 1.0 1.4 0.7 1.2 0.3 0.7 0.0 1.1 0.4 12.3 0.1 0.6 0.5 2.1 0.2 0.3 0.5 0.8 0.5 0.0 1.1 0.6 0.0 0.2 0.0 0.2 0.5 0.2 0.6 0.0 0.0 0.1 0.2 0.3 0.0 1.0 0.0 0.3 0.1 0.0 1.1 0.0 0.4 0.0 0.0 0.1 0.3 0.5 1.5 0.6 0.0 0.2 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.0 0.9 2.2 0.7 0.1 0.5 0.3 0.4 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HSH2D "ALX, FLJ14886, HSH2" ENSG00000196684 "Hematopoietic SH2 domain containing" Q96JZ2 19 16134028-16158575 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 47.0;lymphoid tissue: 37.7" "Cell type enhanced" "Detected in many" "B-cells: 78.5;dendritic cells: 101.3;Gastric mucus-secreting cells: 40.2;NK-cells: 82.4;Plasma cells: 134.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "basophil: 232.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.0;HL-60: 43.5;HMC-1: 56.4;NB-4: 140.1;RPMI-8226: 63.2;U-266/84: 41.9;U-937: 137.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036616 Approved "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA036616: AB_10671962" "unprognostic (1.69e-1)" "unprognostic (2.97e-2)" "prognostic unfavorable (9.46e-6)" "unprognostic (1.06e-1)" "unprognostic (5.50e-3)" "unprognostic (5.21e-3)" "unprognostic (9.35e-2)" "unprognostic (4.78e-2)" "unprognostic (4.21e-3)" "unprognostic (9.96e-2)" "unprognostic (1.57e-2)" "unprognostic (2.22e-2)" "prognostic unfavorable (6.49e-6)" "unprognostic (9.17e-3)" "unprognostic (6.18e-2)" "unprognostic (3.21e-2)" "prognostic favorable (3.47e-5)" 1.6 0.7 0.5 16.8 1.1 47.0 3.3 1.1 1.1 3.0 1.2 9.8 12.7 1.3 1.8 1.7 3.2 5.4 0.4 0.5 0.4 1.5 2.2 5.6 27.2 1.5 0.7 0.5 4.3 2.3 4.0 1.5 1.1 5.1 9.3 0.3 9.5 2.9 0.4 0.4 20.5 1.0 0.7 37.7 12.7 0.4 1.0 8.7 2.6 1.2 35.7 7.5 0.7 2.8 15.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.1 2.2 21.3 41.0 0.6 0.0 0.8 0.7 0.0 0.6 0.0 2.3 0.1 0.6 0.5 2.6 0.0 43.5 56.4 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.1 37.4 0.0 9.0 0.1 140.1 0.0 5.5 0.0 3.0 0.0 63.2 0.4 5.6 0.1 0.1 0.0 1.3 0.3 0.0 0.3 15.9 0.2 0.1 0.1 0.2 0.2 5.7 41.9 23.6 0.2 137.3 0.0 232.1 15.5 100.9 17.1 22.0 15.8 56.4 7.6 11.2 25.5 35.8 6.9 9.2 182.6 85.2 38.8 7.6 13.0 16.7 0.5 1.1 1.1 1.1 0.5 0.4 1.5 0.7 1.1 0.7 1.0 2.8 1.0 3.2 8.9 0.0 78.5 0.3 1.2 3.0 0.6 0.0 3.6 1.9 0.6 5.7 11.3 5.5 0.0 2.6 101.3 18.9 0.0 6.7 0.0 4.5 1.5 0.8 8.4 32.2 0.5 5.1 4.1 0.7 40.2 7.9 6.3 0.1 1.4 0.6 1.1 0.0 0.4 19.1 2.0 3.4 2.4 0.1 0.0 7.3 10.6 1.0 10.7 0.0 82.4 1.0 0.3 9.7 18.0 0.0 134.0 2.6 17.9 0.3 7.9 0.0 0.0 1.1 0.7 0.1 0.5 0.1 0.1 3.4 31.0 0.2 9.3 4.1 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 HSPG2 "perlecan, PRCAN, SJS1" ENSG00000142798 "Heparan sulfate proteoglycan 2" P98160 1 21822244-21937310 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 366.8;Endothelial cells: 322.9;Granulosa cells: 776.0;Hepatic stellate cells: 600.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 293.0;HUVEC TERT2: 620.8;TIME: 504.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009820, HPA018892, CAB020718, HPA072690" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 1400000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB009820: AB_2119229, CAB020718: , HPA018892: AB_1850597, HPA072690: " "unprognostic (1.61e-1)" "unprognostic (1.57e-2)" "unprognostic (4.93e-2)" "unprognostic (9.60e-2)" "unprognostic (2.38e-2)" "unprognostic (8.56e-2)" "unprognostic (4.55e-1)" "unprognostic (1.90e-2)" "unprognostic (9.35e-2)" "unprognostic (2.19e-3)" "unprognostic (5.82e-2)" "unprognostic (2.83e-1)" "unprognostic (1.21e-3)" "unprognostic (1.17e-2)" "unprognostic (4.86e-2)" "unprognostic (1.46e-2)" "prognostic unfavorable (2.82e-4)" 140.7 54.7 3.8 36.1 5.2 1.7 96.2 3.7 4.8 65.9 18.8 153.1 18.3 151.9 6.6 44.1 85.0 53.4 156.6 3.6 2.9 37.6 10.6 49.0 14.2 5.6 4.6 31.3 31.7 13.1 11.8 30.3 5.7 60.3 8.6 0.3 45.0 56.5 65.1 41.0 54.9 96.2 4.0 37.4 76.1 9.0 7.6 6.7 69.1 40.8 3.5 110.2 59.7 4.7 44.0 40.7 13.8 45.9 131.0 99.4 51.5 70.2 17.8 21.1 18.7 50.5 86.7 3.3 293.0 112.9 0.8 26.9 3.1 31.9 5.4 0.6 4.3 15.7 46.0 35.7 27.0 0.0 4.1 61.6 9.4 19.9 6.0 28.1 620.8 0.3 21.4 5.7 32.4 11.8 0.0 20.0 11.7 19.6 17.9 6.3 87.8 6.1 35.1 6.5 1.3 4.1 51.4 20.0 28.7 14.0 8.1 7.2 504.3 41.1 51.8 29.7 2.3 0.5 7.3 2.6 9.7 0.1 54.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 3.8 5.2 3.7 4.8 3.6 2.9 5.6 4.6 5.7 4.0 7.6 4.7 366.8 70.5 28.6 3.6 3.9 26.4 13.5 81.1 21.1 0.6 6.2 21.5 5.8 38.6 30.3 92.0 0.0 11.0 3.4 52.9 0.0 76.1 1.4 24.2 47.7 322.9 2.4 22.9 0.8 25.0 89.0 141.3 62.2 39.8 23.4 776.0 600.4 6.6 6.8 3.3 0.8 12.6 16.2 22.1 19.2 5.8 75.2 4.6 60.5 15.9 1.8 1.6 0.0 2.5 4.3 87.5 29.9 69.2 4.6 19.3 19.2 0.9 28.7 0.6 32.9 82.5 69.8 0.3 4.8 10.0 17.8 9.3 5.0 83.3 20.1 11.8 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HTR7 5-HT7 ENSG00000148680 "5-hydroxytryptamine receptor 7" P34969 10 90740823-90858039 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, RAS pathway related proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 7.6;parathyroid gland: 13.1;testis: 8.7" "Cell type enhanced" "Detected in some" "Early spermatids: 7.0;Excitatory neurons: 5.9;Inhibitory neurons: 24.2;Spermatocytes: 13.1" "Group enriched" "Detected in some" 5 "cervical cancer: 0.9;head and neck cancer: 3.3;lung cancer: 0.9;urothelial cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 12 "myeloid DC: 1.4" "Lineage enriched" "Detected in single" 12 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "HBEC3-KT: 11.3;hTCEpi: 10.1;hTERT-HME1: 33.4;LHCN-M2: 13.5;U-251 MG: 9.6;U-87 MG: 10.2;WM-115: 13.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB022708, HPA073617" Approved Supported Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB022708: , HPA073617: AB_2732228" "unprognostic (1.17e-1)" "unprognostic (1.24e-2)" "unprognostic (4.72e-2)" "unprognostic (1.33e-1)" "unprognostic (5.51e-3)" "unprognostic (1.71e-2)" "unprognostic (1.89e-1)" "unprognostic (1.44e-1)" "unprognostic (1.15e-1)" "unprognostic (4.58e-3)" "unprognostic (3.32e-1)" "unprognostic (1.45e-1)" "unprognostic (2.89e-1)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (1.84e-2)" "unprognostic (6.49e-2)" 0.5 0.2 2.4 0.9 1.4 0.3 0.3 0.0 2.5 0.4 0.4 0.6 0.5 0.2 0.1 0.7 0.2 0.9 0.1 2.7 7.1 0.1 0.4 0.2 0.6 1.5 3.2 0.1 0.2 13.1 0.1 0.3 1.9 0.2 0.9 0.1 0.3 0.1 0.9 0.5 1.4 0.3 0.5 1.1 0.7 8.7 7.6 0.2 0.1 0.5 0.3 2.3 0.6 0.8 0.3 0.0 0.0 0.0 0.2 0.9 0.0 0.7 0.3 0.7 1.0 0.0 1.2 0.0 0.0 0.1 2.0 4.7 1.3 11.3 2.8 0.0 0.2 0.0 0.0 0.0 5.1 0.0 0.6 7.8 10.1 3.3 33.4 6.3 0.0 0.0 0.1 0.0 13.5 0.0 0.0 0.2 1.2 0.0 1.6 1.0 0.1 0.0 0.0 1.2 0.4 0.0 0.5 0.0 5.4 0.6 0.0 0.2 0.3 6.1 0.0 0.1 9.6 0.0 0.0 0.0 10.2 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.4 1.4 0.0 2.5 2.7 7.1 1.5 3.2 1.9 0.5 7.6 0.8 0.1 0.0 0.0 0.7 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.0 0.3 0.0 0.0 0.4 5.9 0.0 0.0 0.1 0.0 0.1 0.0 0.4 0.4 0.0 1.7 0.0 24.2 0.0 2.0 2.2 0.0 2.7 0.0 2.5 0.0 0.0 0.4 0.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.1 13.1 1.3 0.0 0.1 0.1 0.2 0.0 0.0 0.3 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873020-32044633 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 9.8" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 109.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;BEWO: 16.3;RH-30: 18.1;SCLC-21H: 14.8;SiHa: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA027295: AB_2672203, HPA027372: AB_2672239" "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 0.7 1.0 0.8 1.3 1.3 0.2 1.2 0.4 4.7 0.4 0.0 3.6 1.4 4.1 1.9 0.4 1.9 0.5 0.4 4.2 2.6 3.7 0.5 0.9 0.4 0.4 0.1 0.6 9.8 0.1 1.1 4.6 0.1 0.9 3.7 3.0 0.6 2.1 0.3 3.0 2.7 2.4 0.0 0.1 1.3 0.9 0.2 0.7 0.6 0.2 0.6 1.5 0.7 1.6 0.0 3.9 13.2 0.1 0.0 0.0 16.3 1.3 0.0 0.2 0.0 5.3 0.1 0.0 0.5 6.2 0.2 0.0 7.7 0.0 0.1 0.1 3.9 0.0 3.7 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 1.1 0.2 1.1 10.2 0.1 0.1 0.1 18.1 0.1 1.3 0.0 14.8 9.8 13.2 1.0 0.5 9.3 5.5 1.4 0.0 0.1 9.3 0.1 0.0 0.1 0.0 1.8 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.4 4.7 4.2 2.6 0.4 0.1 0.1 0.0 0.2 1.6 0.2 6.4 9.1 7.5 0.0 5.1 2.6 0.2 0.6 8.1 0.5 2.8 3.5 14.3 3.0 7.3 2.1 9.2 0.0 4.6 0.0 5.3 0.2 1.2 1.3 0.8 4.9 0.0 19.0 3.3 13.9 7.9 0.5 3.4 0.0 4.3 0.4 1.0 2.7 3.3 109.6 5.1 0.0 0.0 4.2 0.1 0.3 0.4 3.6 1.0 0.1 8.1 0.0 10.1 1.5 1.6 4.4 0.0 0.0 2.1 1.8 1.9 0.8 1.2 0.0 6.3 2.2 0.7 1.1 0.7 5.8 6.2 0.5 0.0 10.6 0.9 HYDIN "CILD5, DKFZp434D0513, KIAA1864, PPP1R31" ENSG00000157423 "HYDIN axonemal central pair apparatus protein" Q4G0P3 16 70802084-71230722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.9;choroid plexus: 23.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;Endometrial ciliated cells: 150.6;Excitatory neurons: 49.2;Respiratory ciliated cells: 153.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.8;RPTEC TERT1: 2.8;SiHa: 5.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA067155, HPA074129" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA067155: AB_2685792, HPA074129: AB_2686665" "unprognostic (8.90e-2)" "unprognostic (1.04e-2)" "unprognostic (8.65e-2)" "unprognostic (4.88e-4)" "unprognostic (4.25e-3)" "unprognostic (1.81e-1)" "unprognostic (3.87e-2)" "unprognostic (2.45e-1)" "unprognostic (3.95e-1)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (2.52e-5)" "unprognostic (2.13e-3)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (3.97e-2)" 0.3 0.3 2.2 0.3 3.2 0.5 0.5 1.2 1.4 1.2 23.9 0.6 0.2 0.9 2.0 0.1 5.3 0.5 0.5 3.4 3.5 1.3 0.5 1.4 0.3 8.9 9.9 1.1 0.7 2.5 4.4 0.1 5.8 0.8 0.1 6.4 0.3 0.3 0.1 0.5 0.2 0.1 8.0 0.4 0.2 4.7 4.3 0.0 1.9 0.0 0.0 0.5 0.4 4.4 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.1 1.8 0.3 0.1 0.1 0.6 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 1.1 0.2 0.0 0.0 0.0 0.4 0.4 0.7 0.0 0.4 0.1 0.1 0.4 2.8 0.4 1.1 0.2 5.3 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.4 0.0 0.1 0.9 0.0 0.5 0.4 0.1 0.3 0.5 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.7 0.1 0.3 0.2 0.1 0.0 2.2 3.2 1.2 1.4 3.4 3.5 8.9 9.9 5.8 8.0 4.3 4.4 0.1 3.2 2.6 35.3 0.0 0.0 0.2 2.6 0.0 17.0 1.5 1.1 2.5 0.0 18.3 9.2 52.1 0.0 0.4 0.0 1.9 2.5 35.4 150.6 6.5 0.7 3.5 0.0 49.2 0.6 0.0 1.4 0.0 4.0 0.0 5.0 0.0 0.0 0.1 0.0 25.9 0.1 4.1 0.0 0.0 31.5 2.5 0.3 3.6 3.7 0.0 9.3 0.0 26.2 21.8 0.3 0.1 4.5 0.1 0.6 0.0 1.8 153.2 30.5 0.0 2.0 1.7 17.7 7.5 0.0 0.0 0.0 0.5 1.6 0.1 0.2 HYI HT036 ENSG00000178922 "Hydroxypyruvate isomerase (putative)" Q5T013 1 43450989-43453989 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal enterocytes: 232.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 29.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 97.7;HUVEC TERT2: 106.7;U-251 MG: 99.2;WM-115: 105.5" "Low region specificity" "Detected in all" HPA040092 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" No No "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA040092: AB_10795374" "prognostic favorable (9.18e-4)" "unprognostic (1.67e-1)" "prognostic unfavorable (4.96e-4)" "unprognostic (2.68e-2)" "unprognostic (3.86e-1)" "unprognostic (4.40e-2)" "prognostic unfavorable (5.55e-4)" "unprognostic (2.75e-2)" "unprognostic (1.42e-1)" "unprognostic (2.34e-2)" "unprognostic (1.10e-2)" "unprognostic (4.43e-2)" "prognostic unfavorable (2.75e-5)" "unprognostic (5.10e-2)" "unprognostic (7.93e-2)" "unprognostic (3.58e-2)" "prognostic favorable (2.72e-5)" 31.7 22.8 28.1 9.3 29.2 12.1 19.3 29.6 36.3 23.4 27.9 21.3 44.1 23.3 15.4 15.0 24.2 18.7 20.8 27.0 31.2 29.5 44.6 23.0 11.3 30.9 28.9 42.1 53.7 25.2 14.6 10.5 30.9 19.8 12.3 4.1 35.3 47.0 20.8 16.2 34.4 13.2 30.0 12.2 23.9 3.9 28.4 8.8 19.1 10.2 9.2 17.4 15.3 32.4 58.7 7.3 2.2 3.5 9.8 15.1 0.2 48.4 35.7 52.6 34.3 24.2 97.7 0.0 4.1 29.7 25.1 10.9 0.0 45.8 21.6 15.2 20.5 10.2 25.0 0.0 58.8 0.0 0.0 9.4 12.4 64.0 0.0 56.3 106.7 0.5 1.2 0.0 34.5 1.2 9.6 8.8 11.1 5.6 15.5 46.0 0.0 0.3 37.5 2.2 27.2 20.3 56.0 30.4 13.2 8.7 9.2 72.0 59.5 3.7 0.0 12.4 99.2 0.0 0.0 0.0 4.1 13.4 105.5 10.6 1.7 3.7 4.2 1.3 5.5 4.3 7.1 3.3 5.8 5.3 6.6 2.0 0.1 7.5 1.8 29.9 0.7 4.0 28.1 29.2 29.6 36.3 27.0 31.2 30.9 28.9 30.9 30.0 28.4 32.4 29.8 19.2 64.4 5.9 16.1 28.0 45.2 22.8 51.8 16.9 41.0 65.3 0.4 65.8 23.0 57.0 10.4 18.6 19.2 56.6 45.0 106.7 1.2 9.9 23.6 23.2 69.5 21.5 1.4 86.1 115.9 45.7 25.5 18.7 43.2 33.5 25.0 59.0 29.8 8.4 1.9 89.1 16.2 8.5 31.0 4.5 31.7 23.5 40.9 1.9 15.8 45.0 8.2 4.5 4.8 109.6 97.0 30.5 41.7 33.7 232.5 146.9 12.4 16.7 26.3 31.3 58.2 1.4 3.0 27.3 22.0 12.0 12.3 49.8 47.6 38.4 HYLS1 FLJ32915 ENSG00000198331 "HYLS1 centriolar and ciliogenesis associated" Q96M11 11 125883614-125900646 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.5" "Cell type enhanced" "Detected in many" "Early spermatids: 80.8;Late spermatids: 54.9;Spermatocytes: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041210 Enhanced Supported "Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA041210: AB_10794987" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (3.53e-3)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.28e-1)" "unprognostic (1.04e-3)" "unprognostic (6.56e-3)" "unprognostic (7.63e-2)" "unprognostic (4.81e-3)" "unprognostic (3.00e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" 2.9 2.4 5.7 3.0 5.3 2.4 4.3 8.0 8.5 4.2 4.9 4.7 6.0 3.8 6.7 3.7 4.2 2.6 5.0 5.4 5.3 5.5 5.8 2.5 6.2 5.0 4.7 3.9 2.2 2.7 2.3 4.4 5.0 5.0 5.0 4.3 3.1 6.1 2.7 4.8 3.3 6.4 4.5 3.6 5.4 26.5 6.0 5.2 2.5 4.3 9.0 3.8 2.3 5.2 11.2 23.9 8.4 5.9 16.5 11.6 14.8 27.3 10.9 24.8 16.9 0.3 17.2 5.0 11.3 25.4 8.4 15.8 12.2 10.0 28.7 27.1 9.2 3.5 2.3 4.9 12.9 12.4 16.9 7.2 11.0 25.2 28.3 5.1 18.4 11.0 6.1 27.3 33.6 18.6 9.1 36.2 18.4 46.2 40.8 19.0 0.1 16.5 27.3 17.9 11.6 7.2 29.6 22.2 11.0 10.5 53.6 26.9 16.7 1.8 20.9 19.4 4.6 10.1 11.4 11.4 5.1 26.7 22.2 5.7 7.6 1.5 10.6 8.7 10.2 16.1 13.8 12.6 10.0 16.1 13.2 9.7 1.1 6.8 6.3 20.4 15.5 7.1 5.7 5.3 8.0 8.5 5.4 5.3 5.0 4.7 5.0 4.5 6.0 5.2 3.9 0.0 0.5 2.6 9.3 4.2 2.8 8.0 4.6 7.1 4.1 5.3 5.5 1.5 2.2 1.8 4.2 18.6 11.5 4.0 11.7 5.5 80.8 5.8 3.4 3.7 4.9 9.1 14.3 4.2 13.0 5.9 8.6 2.1 0.0 7.1 6.8 5.4 7.6 0.0 13.8 3.2 8.2 3.2 4.0 54.9 8.4 2.5 7.2 6.5 11.9 5.8 12.3 6.0 5.8 3.6 5.8 6.0 4.2 3.3 5.2 12.1 4.8 6.5 6.6 2.3 5.7 92.1 32.3 6.2 4.3 4.4 4.9 7.5 5.5 1.5 ICAM1 "BB2, CD54" ENSG00000090339 "Intercellular adhesion molecule 1" P05362 19 10271093-10286615 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 219.3;urinary bladder: 215.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 612.2;Alveolar cells type 2: 561.6;Endothelial cells: 240.8;Langerhans cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 158.3;Karpas-707: 459.7;RPMI-8226: 148.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002126, CAB002142, HPA004877" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA 87900000 2200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Vesicles, Cytosol" "CAB002142: AB_563596, HPA002126: AB_1078470, HPA004877: AB_1846317" "prognostic favorable (7.09e-4)" "unprognostic (1.88e-1)" "unprognostic (1.94e-1)" "unprognostic (2.63e-2)" "unprognostic (3.25e-3)" "unprognostic (3.05e-1)" "unprognostic (1.45e-2)" "unprognostic (3.48e-1)" "unprognostic (3.18e-2)" "unprognostic (1.09e-2)" "unprognostic (1.49e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (1.32e-6)" "unprognostic (2.77e-1)" "unprognostic (2.16e-2)" "unprognostic (2.25e-1)" "unprognostic (3.70e-3)" 87.9 23.6 9.1 44.6 9.6 117.1 32.4 7.9 12.0 11.2 9.9 17.7 16.8 23.9 3.5 11.0 26.2 56.4 39.1 8.8 9.9 43.9 67.1 219.3 38.3 12.3 8.7 13.0 11.1 8.3 9.3 27.8 10.2 22.2 18.1 10.5 18.0 6.3 15.1 17.9 22.6 23.4 10.0 55.9 21.5 5.6 15.4 28.4 30.8 12.8 32.9 215.3 12.5 10.2 46.3 0.5 7.9 0.2 2.0 4.4 9.7 8.6 91.6 21.8 62.0 14.0 49.8 39.6 130.3 3.8 99.3 8.9 1.7 0.4 45.6 123.8 0.1 3.8 1.4 62.0 158.3 1.3 23.9 55.7 4.0 13.7 20.3 2.0 10.7 4.9 15.0 459.7 1.5 3.3 0.5 34.9 3.1 0.5 24.7 1.0 0.2 148.5 36.8 0.3 0.3 1.1 61.2 3.3 94.5 3.7 6.9 2.8 34.3 22.3 1.9 12.3 0.8 137.4 142.7 25.5 35.1 26.3 32.6 5.0 28.3 5.2 5.3 25.8 9.8 3.8 4.0 6.3 24.7 1.5 1.9 3.8 40.8 15.2 17.0 14.1 6.1 20.8 9.1 9.6 7.9 12.0 8.8 9.9 12.3 8.7 10.2 10.0 15.4 10.2 150.3 612.2 561.6 0.3 31.7 85.3 22.2 62.6 28.5 0.0 50.2 24.9 1.1 21.5 133.5 3.7 0.0 1.1 28.9 2.9 0.0 176.8 2.0 14.1 15.5 240.8 2.4 1.3 0.5 98.7 3.3 136.6 13.7 29.8 139.8 0.1 48.2 12.1 86.7 0.0 0.4 0.7 32.6 53.6 232.6 1.3 4.7 168.3 76.5 7.5 101.9 4.6 5.2 0.5 0.2 113.7 0.3 1.5 57.6 27.1 0.3 15.0 83.2 0.4 6.6 38.2 57.6 0.8 1.6 4.3 69.3 1.2 28.8 0.5 1.6 14.1 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 ICOSLG "B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653" ENSG00000160223 "Inducible T cell costimulator ligand" O75144 21 44217014-44240966 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, B-cell activation, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2;brain: 33.3" "Cell type enhanced" "Detected in many" "B-cells: 28.5;Glandular and luminal cells: 22.7;Langerhans cells: 39.0;monocytes: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "CAB026037, HPA029179, CAB079997" Approved Approved "Plasma membrane,Cytoplasmic bodies" NA NA 130000000 "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytoplasmic bodies" "CAB026037: , CAB079997: , HPA029179: AB_2732445" "unprognostic (3.03e-2)" "unprognostic (1.40e-4)" "unprognostic (3.52e-2)" "unprognostic (1.94e-2)" "unprognostic (6.74e-2)" "unprognostic (9.40e-2)" "unprognostic (6.94e-2)" "unprognostic (3.71e-1)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-1)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.84e-1)" 3.1 3.6 12.1 4.9 21.8 18.2 2.6 10.7 17.9 3.9 0.2 2.1 2.5 1.9 1.4 5.4 3.4 4.1 5.2 11.7 12.4 8.3 3.3 3.1 8.0 18.7 17.9 0.8 2.1 0.7 1.4 3.1 17.1 3.3 1.8 1.4 3.0 1.4 1.5 6.6 3.8 1.3 11.0 4.3 4.9 1.4 18.2 2.6 2.3 1.8 5.5 3.2 3.5 33.3 0.5 4.6 0.2 3.9 1.0 1.5 10.4 1.0 0.9 0.5 0.3 7.9 0.6 19.9 2.9 0.5 1.8 5.8 2.7 1.6 0.3 2.0 2.0 0.6 4.0 2.3 0.9 8.7 14.1 1.4 2.6 1.2 1.3 0.3 1.1 0.7 3.3 1.7 0.3 5.2 0.4 11.4 2.7 13.2 4.8 17.1 1.3 11.6 0.8 10.3 2.0 0.1 12.9 18.2 0.4 1.4 5.1 12.2 1.1 0.6 4.4 0.4 0.4 16.4 12.2 16.2 5.8 8.0 2.5 0.3 0.3 0.2 0.1 0.3 0.1 1.8 0.3 0.1 0.2 2.4 0.3 0.4 0.3 0.2 0.2 0.7 0.1 0.2 12.1 21.8 10.7 17.9 11.7 12.4 18.7 17.9 17.1 11.0 18.2 33.3 1.2 0.0 1.5 0.3 28.5 7.5 5.8 8.4 3.4 1.7 8.7 5.8 0.6 1.5 2.4 9.2 0.0 0.4 2.0 7.9 0.0 2.0 1.9 9.8 2.1 4.6 5.3 0.8 0.0 0.7 1.1 5.6 4.6 22.7 0.0 0.2 1.4 2.8 3.7 0.0 0.0 4.5 8.2 8.8 39.0 4.0 3.1 15.6 8.8 0.0 21.0 1.2 2.1 0.0 0.5 0.8 3.8 10.9 4.7 16.0 3.6 3.5 0.6 1.2 0.0 4.5 6.1 0.1 0.2 4.7 6.5 0.5 2.9 0.3 4.5 7.9 IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.0;Basal prostatic cells: 83.0;Suprabasal keratinocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "HDLM-2: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" 5.3 9.2 7.4 8.2 6.6 10.4 12.6 19.6 10.6 12.3 0.6 9.0 2.0 7.4 2.4 43.0 5.2 7.0 4.2 6.4 7.9 6.8 5.8 7.5 8.6 11.2 9.3 3.3 19.1 10.7 6.5 7.2 9.7 9.4 2.8 4.3 14.4 9.1 7.9 169.9 3.9 7.1 6.8 6.3 4.4 1.8 9.6 6.2 6.4 4.2 14.0 8.5 21.6 8.8 23.3 37.2 9.9 27.4 6.2 4.9 16.0 17.2 11.4 9.2 6.4 51.5 26.6 0.3 21.6 13.1 10.6 57.6 7.6 36.6 7.4 139.3 6.7 0.4 7.1 20.4 4.5 4.0 21.3 3.2 36.3 12.4 15.7 15.2 19.9 1.2 1.4 4.6 6.1 4.9 3.9 3.7 4.2 23.9 8.8 13.1 6.1 9.8 5.4 14.9 31.6 1.7 13.1 18.2 12.6 10.1 4.9 2.1 54.6 12.4 17.2 7.3 50.5 9.7 11.3 0.8 8.3 5.7 14.8 12.6 0.2 0.0 0.4 0.3 0.5 0.5 0.3 0.4 0.1 0.2 0.3 0.6 0.0 0.2 0.0 0.4 0.3 0.1 7.4 6.6 19.6 10.6 6.4 7.9 11.2 9.3 9.7 6.8 9.6 8.8 4.1 3.2 5.4 5.5 6.0 121.0 83.0 24.1 40.5 6.8 11.5 13.5 6.8 12.8 9.7 1.8 0.0 5.1 20.9 4.9 1.9 17.3 1.3 23.3 5.9 7.7 2.4 3.2 8.5 17.6 5.4 4.7 3.1 10.2 3.8 0.8 4.6 3.4 2.4 25.2 9.6 1.3 2.0 1.6 17.1 4.5 1.2 6.8 14.2 1.0 3.5 4.4 8.2 11.6 8.8 14.6 3.3 3.0 15.5 15.0 0.8 9.3 23.1 1.8 0.0 3.5 7.5 0.8 0.4 32.4 100.3 4.0 13.9 0.4 1.3 44.2 IFIT5 RI58 ENSG00000152778 "Interferon induced protein with tetratricopeptide repeats 5" Q13325 10 89414568-89421605 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 109.1;BJ hTERT+ SV40 Large T+ RasG12V: 128.0" "Low region specificity" "Detected in all" "HPA037957, HPA062180" Uncertain Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA037957: AB_10672499, HPA062180: AB_2684705" "unprognostic (2.17e-1)" "unprognostic (1.85e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.67e-3)" "unprognostic (4.19e-2)" "unprognostic (2.88e-2)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (8.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (3.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (2.43e-2)" "unprognostic (1.73e-1)" 13.3 11.6 11.9 11.1 14.3 16.1 9.7 18.7 13.5 11.4 25.0 9.4 9.4 10.2 9.1 7.4 11.2 12.6 14.6 10.8 14.5 14.2 14.1 17.1 13.2 14.7 13.0 14.1 9.2 22.8 3.7 14.6 14.4 9.7 8.9 9.0 12.2 10.5 3.7 5.5 11.1 14.2 19.2 18.6 9.1 6.3 12.5 10.5 10.8 6.4 11.3 12.3 4.6 16.8 41.8 12.5 17.3 56.9 46.7 43.4 3.7 33.2 59.5 109.1 128.0 1.0 19.0 1.8 12.1 38.7 42.8 34.8 20.9 19.3 26.0 17.8 13.1 5.0 8.9 7.8 52.4 0.4 3.1 34.9 7.4 32.0 23.7 30.8 6.2 10.8 0.0 29.4 30.8 7.7 12.6 3.8 2.2 0.0 21.9 11.0 20.0 4.6 23.7 5.1 1.9 11.1 18.2 6.6 51.6 4.7 6.2 3.5 15.5 14.0 10.3 23.2 20.0 3.8 0.6 0.2 24.2 3.3 11.6 24.7 15.7 19.3 13.9 25.6 16.4 21.4 14.7 13.0 14.2 18.1 16.8 14.1 45.2 8.3 32.1 1.3 14.1 12.3 11.9 14.3 18.7 13.5 10.8 14.5 14.7 13.0 14.4 19.2 12.5 16.8 24.8 6.4 14.8 3.6 12.8 8.5 35.7 15.2 13.6 8.3 4.4 4.3 8.9 11.5 12.4 9.2 0.0 6.3 7.5 7.2 11.7 13.7 0.1 11.2 17.1 23.1 4.9 2.1 3.6 9.1 11.5 17.9 6.1 13.3 15.2 6.2 12.1 16.5 11.0 35.3 7.2 5.5 6.1 8.9 6.0 1.0 21.1 10.8 7.2 4.7 12.3 14.6 7.2 4.5 10.2 10.5 5.9 17.3 6.8 21.0 7.5 17.0 9.6 5.3 19.7 15.4 14.2 17.2 14.4 7.7 3.8 4.5 9.3 4.7 2.5 29.1 IFITM1 "9-27, CD225, DSPA2a, IFI17" ENSG00000185885 "Interferon induced transmembrane protein 1" P13164 11 310041-315272 "CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity, Osteogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 673.8;Endothelial cells: 364.4;Leydig cells: 300.8;Sertoli cells: 276.1;T-cells: 595.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "eosinophil: 1494.7;gdT-cell: 2906.3;MAIT T-cell: 2003.4;memory CD4 T-cell: 3120.6;memory CD8 T-cell: 3000.3;naive CD4 T-cell: 2939.3;naive CD8 T-cell: 2996.4;neutrophil: 2741.6;NK-cell: 4679.9;T-reg: 1944.8" "Group enriched" "Detected in all" 7 "granulocytes: 2741.6;NK-cells: 4679.9;T-cells: 3120.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 1038.8;BJ hTERT+ SV40 Large T+: 2266.3;BJ hTERT+ SV40 Large T+ RasG12V: 4016.8;HMC-1: 1138.9" "HPA004810, CAB017615" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 58: T-cells - T-cell receptor" "Golgi apparatus" "Plasma membrane, Cytosol" "CAB017615: AB_2264496, HPA004810: AB_1851419" "unprognostic (1.03e-3)" "unprognostic (6.79e-2)" "unprognostic (1.03e-1)" "unprognostic (2.98e-1)" "unprognostic (2.57e-1)" "unprognostic (9.06e-2)" "unprognostic (7.58e-2)" "unprognostic (3.03e-1)" "unprognostic (6.21e-2)" "unprognostic (5.53e-2)" "unprognostic (6.64e-3)" "unprognostic (1.48e-2)" "prognostic unfavorable (5.77e-9)" "unprognostic (7.29e-2)" "unprognostic (6.29e-2)" "unprognostic (3.15e-2)" "unprognostic (3.82e-2)" 477.7 102.3 291.8 282.0 303.4 367.1 401.7 293.8 402.1 563.3 321.5 249.0 128.4 314.6 1152.4 147.4 537.4 247.9 368.4 292.6 305.4 317.5 191.4 246.5 417.2 324.8 295.6 607.5 78.8 154.0 145.1 278.5 322.5 190.6 172.0 14.9 199.8 324.3 134.2 164.6 252.4 367.4 308.6 679.7 141.6 56.3 317.5 296.5 263.4 259.3 295.9 307.4 364.7 304.3 125.7 5.5 1011.4 74.5 79.1 279.8 7.4 250.1 1038.8 2266.3 4016.8 3.7 782.2 3.0 157.9 257.1 23.5 269.0 36.5 26.2 52.0 255.3 51.8 125.9 77.5 11.8 668.2 182.8 1138.9 496.3 0.2 26.6 2.6 27.0 4.2 41.1 450.0 880.7 1.7 23.9 85.1 318.2 264.5 0.5 33.5 27.1 3.1 24.5 654.9 0.0 1.0 2.2 122.7 11.9 196.9 138.5 42.1 17.0 8.8 3.8 4.7 1.5 1.1 61.6 44.8 6.8 3.4 253.8 3.1 544.4 62.1 1494.7 2906.3 312.7 2003.4 364.9 3120.6 3000.3 114.2 323.6 2939.3 2996.4 2741.6 4679.9 539.0 33.7 1944.8 4673.8 291.8 303.4 293.8 402.1 292.6 305.4 324.8 295.6 322.5 308.6 317.5 304.3 240.7 35.3 119.4 2.6 88.2 27.9 17.1 70.2 673.8 0.0 13.0 12.6 8.4 2.8 115.3 33.1 0.0 3.3 258.6 13.7 5.9 1.7 1.4 14.6 96.5 364.4 1.2 27.8 0.0 1.4 30.7 236.0 33.6 20.8 18.9 5.6 164.6 24.6 11.8 0.0 0.0 17.3 10.2 10.1 26.8 3.8 300.8 45.4 78.2 42.2 2.1 0.0 126.7 0.0 0.2 0.7 15.0 124.5 141.2 2.3 15.0 1.0 26.0 0.0 276.1 16.4 213.4 0.6 1.5 50.4 14.3 4.0 595.8 2.1 29.2 5.7 IFITM2 "1-8D, DSPA2c" ENSG00000185201 "Interferon induced transmembrane protein 2" Q01629 11 303655-309397 "Predicted membrane proteins, Transporters" "Antiviral defense, Immunity, Innate immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 920.0;NK-cells: 1350.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 23410.9" "Lineage enriched" "Detected in all" 11 "granulocytes: 23410.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 424.6;HHSteC: 547.7;HMC-1: 494.9;HSkMC: 710.9;NB-4: 603.3;U-937: 485.2" "HPA004337, HPA044731" Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA 450000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" "Cell Junctions" Nucleoplasm "HPA004337: AB_1851427, HPA044731: " "unprognostic (2.39e-2)" "unprognostic (2.69e-2)" "unprognostic (4.54e-1)" "unprognostic (1.65e-2)" "unprognostic (3.41e-2)" "unprognostic (1.86e-1)" "unprognostic (3.56e-2)" "unprognostic (3.87e-2)" "unprognostic (3.87e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-3)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.37e-9)" "unprognostic (2.79e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-1)" "unprognostic (1.16e-2)" 1086.2 307.0 90.3 258.0 90.2 177.0 681.0 89.6 116.6 785.6 101.4 358.6 40.9 702.8 52.1 237.2 903.8 97.4 619.6 92.0 97.9 703.1 1288.5 1069.9 99.9 94.4 89.4 650.1 211.1 112.0 200.6 145.3 94.9 406.1 41.8 27.0 228.9 102.5 195.9 236.7 305.6 200.4 92.8 1402.1 304.3 123.0 95.4 29.8 437.7 132.8 105.8 493.1 496.6 95.1 32.2 65.4 313.1 2.9 137.2 358.3 0.9 106.8 65.1 27.0 63.3 1.7 206.9 2.7 126.6 424.6 0.4 68.5 1.1 9.3 9.0 1.8 41.1 75.1 102.6 117.6 547.7 124.1 494.9 710.9 2.3 5.2 3.3 64.4 51.2 22.5 5.2 210.5 11.6 129.9 2.5 603.3 36.4 5.3 229.4 101.0 29.9 1.1 181.6 0.4 0.8 7.0 65.4 74.9 34.5 5.3 86.7 69.8 338.3 5.7 26.8 36.1 1.4 4.5 5.0 3.3 14.5 485.2 18.1 2706.4 537.4 3789.5 666.6 1421.9 480.8 846.9 590.1 639.5 612.5 799.2 511.7 510.3 23410.9 1225.0 2199.0 279.0 411.7 1376.6 90.3 90.2 89.6 116.6 92.0 97.9 94.4 89.4 94.9 92.8 95.4 95.1 920.0 307.7 540.0 5.9 301.1 104.4 251.1 161.4 215.1 0.3 59.7 66.5 51.8 154.4 209.2 248.3 0.0 8.3 814.7 22.5 487.2 433.0 7.8 67.1 468.6 828.4 9.6 100.7 0.0 256.7 16.9 515.8 30.5 78.5 530.5 68.8 752.1 684.1 223.4 0.0 0.0 39.4 24.4 372.8 255.9 31.5 507.6 645.9 209.9 12.2 177.3 80.5 1350.1 0.0 0.1 161.9 149.2 223.8 123.0 126.3 4.7 45.3 104.8 1.5 315.5 442.5 568.4 8.4 10.4 22.8 83.0 23.4 667.2 61.8 44.3 102.4 IFITM5 "BRIL, DSPA1, fragilis4, Hrmp1" ENSG00000206013 "Interferon induced transmembrane protein 5" A6NNB3 11 298200-299526 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Mineral balance" "Developmental protein" "Disease variant, Osteogenesis imperfecta" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 4.9;pancreas: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in single" 8 "cerebral cortex: 4.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Karpas-707: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA039258 Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Vesicles, Cytosol" "HPA039258: AB_10673608" "unprognostic (9.84e-2)" "unprognostic (2.15e-1)" "unprognostic (1.38e-1)" "unprognostic (5.80e-2)" "unprognostic (7.46e-2)" "unprognostic (4.20e-2)" "unprognostic (4.42e-2)" "unprognostic (8.31e-2)" "unprognostic (7.99e-3)" "unprognostic (1.94e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (4.90e-2)" 0.1 0.0 0.0 0.1 0.0 0.7 0.2 0.0 4.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.2 0.4 0.1 0.1 0.1 0.0 7.3 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.1 0.1 0.6 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197485-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 867.1;Club cells: 405.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" 155.5 59.3 54.6 131.5 57.8 146.2 121.4 64.5 72.1 74.1 56.8 74.7 97.9 58.1 67.4 65.0 55.7 88.4 103.7 53.1 59.9 44.4 104.0 153.8 140.2 71.9 60.3 43.3 44.5 47.4 26.3 86.1 75.9 53.2 74.4 40.4 57.7 57.4 58.3 66.2 101.2 75.9 69.2 165.9 51.3 27.9 59.9 69.2 58.3 75.5 135.2 112.6 58.0 85.0 23.2 23.4 25.1 33.4 166.8 86.7 23.0 67.0 90.0 38.0 53.3 148.7 39.8 24.5 99.2 36.1 55.1 130.0 24.1 62.6 51.5 49.4 37.4 36.1 23.3 192.9 97.3 112.9 46.6 195.9 232.6 33.3 51.4 36.1 48.7 29.1 32.0 34.9 29.2 27.7 17.7 47.0 22.0 191.9 18.6 51.3 28.4 32.1 65.5 104.4 27.4 39.5 77.3 41.9 57.5 47.8 15.5 68.7 71.1 36.2 27.7 48.5 31.8 25.3 25.5 23.8 19.4 69.2 36.5 158.6 518.4 356.3 106.9 502.6 224.7 91.3 60.0 90.0 309.4 98.3 39.2 43.1 736.0 48.4 375.6 85.1 48.0 519.3 54.6 57.8 64.5 72.1 53.1 59.9 71.9 60.3 75.9 69.2 59.9 85.0 298.7 80.1 59.9 21.5 76.4 127.6 177.6 867.1 84.2 15.4 49.8 37.3 49.6 37.1 405.7 27.6 12.5 78.5 240.8 111.0 7.9 74.2 11.6 91.4 52.7 110.7 13.1 25.7 21.4 101.4 67.1 94.7 33.6 112.8 63.3 10.3 62.8 56.5 149.8 10.1 24.2 25.5 270.6 326.2 220.0 6.1 44.1 261.7 49.8 147.1 138.4 23.5 52.5 25.1 44.9 76.0 57.6 49.2 74.5 129.6 82.0 17.2 150.6 28.1 13.1 45.7 75.7 14.6 22.4 47.3 113.2 209.9 121.5 48.3 33.9 140.2 IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.2;neutrophil: 112.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.3" "Low cell line specificity" "Detected in all" "HPA024122, HPA072413" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA024122: AB_1851452, HPA072413: " "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.10e-1)" "unprognostic (9.82e-3)" "unprognostic (1.36e-2)" "unprognostic (2.39e-1)" "unprognostic (5.73e-3)" "unprognostic (1.37e-1)" "unprognostic (2.48e-2)" "prognostic favorable (5.45e-4)" "unprognostic (6.41e-2)" "unprognostic (2.93e-3)" "unprognostic (1.50e-3)" "unprognostic (4.81e-2)" "unprognostic (1.98e-1)" "unprognostic (2.89e-1)" "unprognostic (4.70e-2)" 35.2 24.6 11.2 6.5 14.4 57.7 32.3 13.2 16.2 23.0 31.7 30.3 8.1 20.8 4.8 24.0 25.4 4.6 30.9 13.9 19.0 21.3 27.3 40.1 3.9 11.0 13.2 31.3 102.9 9.8 31.2 7.9 13.0 28.1 5.5 13.4 25.7 6.4 58.9 21.9 22.2 10.2 11.7 19.9 38.3 24.5 13.1 4.5 25.6 3.1 3.9 24.1 25.8 19.6 22.1 26.8 25.9 21.7 44.4 28.2 25.0 23.8 26.6 36.0 29.6 42.7 21.1 12.2 52.9 18.8 64.6 15.0 21.5 29.2 46.9 17.1 31.7 13.8 46.1 37.9 61.5 19.9 9.5 24.7 43.4 39.7 47.1 18.9 18.3 22.2 46.5 17.4 14.2 35.7 24.1 20.1 51.8 26.9 30.1 24.6 9.2 22.9 6.0 6.1 37.9 18.9 28.0 15.5 61.2 57.7 9.8 15.2 12.6 45.8 10.4 35.0 68.5 27.2 34.8 37.1 12.9 43.6 63.8 19.8 7.6 64.2 7.2 6.5 6.2 8.7 7.7 7.9 6.6 7.2 6.8 7.0 112.3 8.0 6.4 4.6 8.6 5.2 11.2 14.4 13.2 16.2 13.9 19.0 11.0 13.2 13.0 11.7 13.1 19.6 179.3 32.1 31.4 39.2 110.6 197.3 159.3 55.6 259.6 50.3 141.7 142.6 60.6 37.1 55.0 18.4 89.6 66.5 130.9 276.0 17.6 49.6 43.9 123.2 159.7 96.8 138.2 24.6 36.1 56.5 84.2 135.5 162.6 190.1 74.4 51.3 52.8 21.7 126.1 21.9 24.4 183.5 54.9 96.9 153.4 10.1 36.7 141.8 103.2 44.0 55.8 32.4 20.6 24.1 42.6 55.1 287.8 41.0 104.6 143.9 226.9 13.3 34.1 86.8 39.5 138.9 172.7 25.5 14.5 135.1 126.0 151.7 129.8 53.4 180.0 154.4 IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 23.5 15.1 12.2 11.7 12.6 29.1 26.1 12.4 15.2 29.3 14.3 16.3 9.2 27.4 29.0 14.8 38.0 19.0 11.8 12.5 13.5 20.5 7.8 16.9 18.3 12.3 12.8 39.2 15.7 22.5 16.5 17.5 12.8 17.5 17.8 15.1 13.6 23.8 4.7 15.5 11.2 24.3 13.3 15.7 12.2 31.8 14.1 22.8 31.3 9.0 18.9 19.5 18.0 14.2 33.9 25.4 50.3 35.8 41.9 46.4 23.9 20.8 46.1 53.6 51.6 70.5 33.7 18.8 32.8 42.6 43.4 27.7 21.3 37.3 58.6 15.6 20.0 24.8 16.2 65.9 51.4 33.4 16.4 37.8 40.2 34.9 27.0 39.0 42.7 41.4 21.3 26.1 39.9 34.0 46.4 51.5 28.4 22.2 24.9 48.6 57.5 27.8 41.8 32.9 38.8 45.3 63.6 46.7 52.2 25.3 21.8 45.1 26.9 47.3 35.1 26.3 31.1 25.3 26.9 32.8 56.8 24.0 34.8 8.0 22.0 16.8 18.4 20.9 15.0 17.5 14.7 17.5 28.4 15.3 15.4 16.0 6.3 17.4 26.2 21.5 18.6 17.3 12.2 12.6 12.4 15.2 12.5 13.5 12.3 12.8 12.8 13.3 14.1 14.2 21.1 6.4 13.1 11.4 13.7 13.0 12.8 22.4 12.0 11.5 14.1 19.2 2.9 11.5 13.2 7.3 0.0 19.9 16.0 14.8 19.6 26.1 78.4 32.1 19.4 18.1 9.5 23.4 20.5 22.2 19.7 25.3 8.2 10.5 14.5 26.7 23.2 2.6 19.4 8.4 22.5 11.0 14.2 18.2 13.9 20.9 28.6 13.3 17.8 12.2 21.3 22.6 18.6 14.6 25.7 14.8 10.1 38.4 13.5 5.9 5.5 18.3 49.0 12.8 13.1 23.9 24.8 57.3 18.5 12.2 14.9 9.6 12.1 30.4 10.3 10.5 IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 41.6" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Excitatory neurons: 27.1;Inhibitory neurons: 29.3;Oligodendrocytes: 38.5;Spermatocytes: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 65 "CACO-2: 82.4;OE19: 166.9" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Plasma membrane" "HPA059137: AB_2683920" "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" 2.4 0.0 0.2 0.0 0.2 0.0 2.0 0.0 0.8 0.1 0.0 0.5 0.0 0.2 0.5 1.5 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 0.7 0.3 0.0 0.0 1.5 0.3 0.9 0.8 0.0 0.8 0.4 1.0 0.0 0.0 41.6 0.1 0.2 0.2 0.0 0.0 4.1 0.3 1.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 1.7 0.5 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.0 1.6 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 166.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.4 0.7 0.3 0.8 0.2 0.3 2.1 0.0 0.0 0.0 17.9 0.0 2.2 0.0 1.1 0.0 1.7 2.0 1.5 0.6 0.0 0.7 0.0 0.0 4.3 0.0 0.7 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.0 27.1 0.2 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 29.3 0.4 0.0 0.0 0.3 5.4 0.0 0.0 1.8 0.0 0.0 0.2 0.0 6.0 38.5 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 1.9 0.0 0.0 0.7 9.8 8.7 0.0 4.7 2.6 0.2 0.0 1.4 0.0 IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.9" "Cell type enhanced" "Detected in many" "dendritic cells: 29.9;granulocytes: 38.7;Langerhans cells: 33.7;Macrophages: 28.8;monocytes: 115.6;Plasma cells: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 899.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 899.7" "Cell line enhanced" "Detected in many" "HMC-1: 32.9;Karpas-707: 26.0;U-266/70: 34.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" 7.6 10.9 6.1 19.5 6.8 14.4 6.2 6.0 9.3 4.9 6.0 6.5 6.1 3.4 5.5 4.0 6.4 6.1 4.5 5.9 11.1 14.0 49.9 11.3 33.0 9.1 6.8 4.4 9.3 1.4 5.5 4.5 7.4 6.2 6.4 4.6 7.8 1.5 4.5 4.4 13.2 4.4 5.6 28.6 7.9 6.7 7.1 12.6 7.2 2.1 23.2 7.3 3.5 7.5 2.2 10.0 3.5 8.3 1.1 1.7 2.0 1.5 1.1 1.8 4.7 3.0 2.4 4.0 3.2 0.7 0.6 1.6 2.0 2.1 0.9 3.3 5.0 15.0 3.4 9.1 2.8 1.7 32.9 2.7 1.3 3.5 0.8 0.6 1.9 7.7 4.9 26.0 0.5 7.4 5.1 16.7 1.6 9.4 2.7 6.0 3.3 8.3 1.7 3.2 2.4 4.5 3.4 2.4 1.8 1.3 3.4 7.8 0.5 4.2 2.0 2.6 4.0 34.0 7.5 2.8 4.9 5.8 3.0 147.9 190.9 184.1 94.2 167.7 106.6 169.3 107.3 88.8 253.2 172.1 95.8 77.0 208.6 144.9 125.3 899.7 136.3 139.5 6.1 6.8 6.0 9.3 5.9 11.1 9.1 6.8 7.4 5.6 7.1 7.5 0.3 0.0 13.5 2.6 24.5 0.6 0.3 0.0 0.0 0.4 1.3 1.3 1.2 1.5 5.0 0.0 0.0 0.6 29.9 1.2 1.9 1.9 0.0 0.8 0.6 0.8 3.0 6.1 0.3 4.2 1.8 0.9 1.1 0.7 38.7 0.6 2.2 20.3 14.6 0.0 0.4 1.8 0.0 15.7 33.7 0.6 0.0 28.8 5.4 1.9 115.6 2.7 12.3 2.5 1.0 1.4 0.3 0.0 42.1 0.2 0.9 10.8 3.6 0.4 0.0 1.0 0.9 0.4 0.5 1.9 0.9 0.3 20.8 0.4 2.4 0.0 IGSF11 "BT-IgSF, CT119, Igsf13, MGC35227, VSIG3" ENSG00000144847 "Immunoglobulin superfamily member 11" Q5DX21 3 118900557-119146068 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Growth regulation" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 46.3;ovary: 16.2;retina: 50.6;testis: 35.7" "Cell type enhanced" "Detected in many" "Astrocytes: 133.9;Early spermatids: 257.9;Inhibitory neurons: 139.1;Late spermatids: 334.0;Oligodendrocytes: 283.2" "Group enriched" "Detected in many" 9 "glioma: 9.2;melanoma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 8.0;HEL: 5.9;SK-MEL-30: 35.1;U-266/70: 11.9;U-266/84: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046377 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "Nucleoplasm, Cytosol" "HPA046377: AB_10966195" "unprognostic (2.05e-1)" "unprognostic (1.29e-1)" "unprognostic (1.62e-1)" "unprognostic (1.88e-1)" "unprognostic (1.17e-2)" "unprognostic (1.89e-3)" "unprognostic (2.51e-2)" "unprognostic (3.56e-2)" "unprognostic (3.91e-1)" "unprognostic (1.44e-1)" "unprognostic (2.20e-1)" "unprognostic (8.70e-2)" "unprognostic (1.08e-1)" "unprognostic (5.03e-4)" "unprognostic (1.39e-1)" "unprognostic (3.42e-2)" "unprognostic (7.57e-2)" 0.3 7.8 19.5 0.4 34.0 0.0 0.2 26.9 22.2 0.8 1.5 4.1 0.2 0.5 1.1 1.2 0.6 0.8 2.2 19.3 18.6 8.2 0.1 0.1 0.1 30.5 28.0 16.2 3.7 1.3 1.7 0.1 29.9 0.7 0.8 50.6 0.6 0.8 3.9 1.5 0.9 0.5 23.3 0.1 1.6 35.7 25.6 0.3 3.4 5.0 0.2 0.6 0.8 46.3 0.0 8.0 0.2 0.1 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 2.7 0.0 0.0 0.0 0.1 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 0.0 3.1 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.7 0.6 0.0 0.1 35.1 2.1 0.7 0.1 0.0 0.0 1.4 0.0 0.1 11.9 15.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 34.0 26.9 22.2 19.3 18.6 30.5 28.0 29.9 23.3 25.6 46.3 0.1 0.0 0.0 133.9 0.6 0.4 0.1 0.3 2.8 9.1 0.3 0.1 1.3 0.0 0.5 0.0 75.0 0.2 0.1 0.0 0.0 0.9 257.9 4.2 0.8 0.3 0.0 0.0 77.8 0.7 0.0 2.0 0.0 7.2 0.0 26.8 0.0 0.0 0.0 16.8 139.1 0.0 6.1 0.0 0.4 334.0 3.7 0.4 3.6 4.7 0.0 22.3 0.0 43.2 283.2 0.2 0.0 1.9 0.2 0.1 0.0 5.9 0.4 25.7 0.0 0.8 0.9 22.4 6.0 0.7 0.0 0.1 0.2 6.8 0.0 0.4 IGSF23 ENSG00000216588 "Immunoglobulin superfamily member 23" A1L1A6 19 44613563-44636781 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "intestine: 15.9;liver: 24.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 5.7;Early spermatids: 7.9;Hepatocytes: 11.9;Late spermatids: 9.9;Proximal enterocytes: 40.8" "Cancer enriched" "Detected in some" 10 "liver cancer: 12.4" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 5 "neutrophil: 2.4" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.4" "Cell line enhanced" "Detected in some" "CACO-2: 10.5;Hep G2: 5.4;SiHa: 4.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA051811 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA051811: AB_2681621" "unprognostic (1.54e-1)" "unprognostic (1.84e-3)" "unprognostic (5.74e-2)" "unprognostic (1.53e-3)" "unprognostic (4.58e-2)" "unprognostic (1.11e-1)" "prognostic favorable (7.20e-6)" "unprognostic (7.35e-3)" "unprognostic (2.71e-1)" "unprognostic (3.27e-2)" "unprognostic (2.93e-3)" "unprognostic (1.52e-1)" "unprognostic (1.19e-8)" "unprognostic (1.26e-1)" "unprognostic (6.38e-2)" "unprognostic (9.17e-2)" "unprognostic (2.85e-1)" 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.2 14.7 0.1 0.7 0.0 0.0 0.1 0.5 0.1 0.1 0.4 24.5 0.2 0.0 0.4 0.4 0.0 3.7 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 15.9 0.0 0.1 0.0 0.1 1.3 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.3 0.6 0.0 0.3 0.0 0.0 0.5 0.3 0.5 0.0 0.4 10.5 0.3 0.0 0.7 0.3 0.2 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.2 5.4 0.0 0.0 0.1 0.3 0.0 0.6 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 4.7 1.6 0.0 0.0 0.2 0.0 1.9 0.3 0.4 0.4 0.0 0.9 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.4 0.4 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 7.9 0.3 0.0 0.1 0.0 0.0 0.4 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.7 11.9 0.0 0.0 0.4 1.2 0.0 0.3 0.0 9.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.4 1.2 0.0 0.0 0.0 40.8 3.1 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 1.3 0.0 IGSF9B "KIAA1030, LINC00947, LOC283174, MIR4697HG" ENSG00000080854 "Immunoglobulin superfamily member 9B" Q9UPX0 11 133896438-133956968 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.8;choroid plexus: 20.2" "Group enriched" "Detected in some" 4 "Excitatory neurons: 25.2;Inhibitory neurons: 11.6;Oligodendrocyte precursor cells: 30.7" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 38.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 10.0;SCLC-21H: 17.7;SH-SY5Y: 11.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010802 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cell Junctions" "HPA010802: AB_1079194" "unprognostic (9.04e-4)" "unprognostic (1.74e-2)" "unprognostic (7.52e-3)" "unprognostic (4.38e-4)" "unprognostic (8.35e-2)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (6.17e-2)" "unprognostic (1.38e-1)" "unprognostic (8.10e-2)" "unprognostic (2.81e-1)" "unprognostic (2.99e-4)" "unprognostic (3.17e-1)" "unprognostic (2.19e-1)" "unprognostic (1.41e-1)" "unprognostic (9.14e-4)" "unprognostic (3.12e-3)" 1.0 1.4 9.4 1.4 3.8 0.2 0.8 38.8 30.7 2.2 20.2 4.7 0.5 4.8 3.0 2.8 4.6 1.2 6.7 8.3 0.0 0.4 0.0 0.8 0.7 0.0 0.9 1.0 0.9 0.7 2.6 0.6 1.1 2.6 1.3 9.3 0.8 4.1 4.7 2.3 1.3 4.5 0.0 0.9 1.9 3.3 0.0 0.5 2.5 3.5 0.7 2.6 1.6 0.0 0.0 0.6 1.2 0.0 0.0 0.0 4.2 0.1 0.0 0.1 0.0 0.1 2.6 1.6 0.7 0.6 0.3 3.7 3.9 0.0 0.1 2.8 3.1 0.0 0.0 0.0 0.1 1.0 5.1 0.1 0.0 0.0 0.5 0.5 0.0 4.7 0.0 0.0 0.0 1.9 0.5 0.4 2.5 10.0 0.0 0.0 0.0 0.0 0.9 0.0 17.7 11.1 0.1 0.2 0.0 3.7 1.8 0.0 0.0 1.2 1.3 1.0 0.9 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 3.8 38.8 30.7 8.3 0.0 0.0 0.9 1.1 0.0 0.0 0.0 0.4 0.0 0.0 1.3 0.0 3.4 0.1 0.2 0.0 2.9 0.2 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.4 0.0 0.0 0.9 0.0 0.0 25.2 0.2 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.5 0.0 0.0 0.6 0.5 0.0 0.0 0.0 0.0 0.0 1.2 0.0 30.7 0.2 0.1 0.1 0.4 0.0 0.2 0.0 0.1 0.0 0.9 0.0 0.2 0.6 0.0 0.3 0.1 4.8 0.0 0.6 0.1 0.2 0.1 IKZF5 "FLJ22973, Pegasus, ZNFN1A5" ENSG00000095574 "IKAROS family zinc finger 5" Q9H5V7 10 122990807-123008812 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015297, HPA051574" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 35: Glandular cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA015297: AB_1855183, HPA051574: AB_2681538" "unprognostic (2.42e-1)" "unprognostic (1.08e-1)" "unprognostic (4.64e-2)" "unprognostic (2.76e-2)" "unprognostic (1.44e-2)" "unprognostic (1.66e-3)" "unprognostic (2.68e-1)" "unprognostic (9.14e-3)" "unprognostic (5.43e-2)" "unprognostic (2.99e-1)" "unprognostic (6.88e-2)" "unprognostic (1.63e-2)" "unprognostic (3.98e-3)" "unprognostic (4.17e-2)" "unprognostic (6.03e-2)" "unprognostic (6.96e-2)" "unprognostic (3.15e-2)" 8.3 8.5 8.7 7.3 11.5 34.0 12.2 10.2 15.1 8.8 5.9 7.6 6.6 9.3 9.7 7.2 8.4 6.1 7.1 8.3 10.3 8.7 12.2 8.2 11.1 10.4 10.4 13.9 11.1 9.3 10.1 8.1 11.2 8.3 7.1 13.6 8.4 6.0 9.7 11.3 8.5 7.1 10.0 9.2 7.9 10.5 9.8 10.5 10.0 9.4 9.6 7.3 8.4 17.7 7.5 3.7 7.3 12.5 11.5 10.5 7.9 6.2 13.3 8.1 9.8 6.0 8.6 18.8 4.5 7.6 4.4 10.1 13.0 9.3 11.9 10.6 11.5 12.1 6.0 9.0 7.6 14.8 10.6 8.3 12.5 9.7 20.8 11.1 9.0 12.3 16.9 12.2 8.8 5.5 13.6 16.1 6.7 5.6 5.1 10.9 9.1 10.8 6.7 5.1 7.9 7.1 5.1 6.3 12.2 5.8 5.2 9.3 9.3 5.8 4.9 8.6 10.1 11.4 6.6 17.6 7.4 25.5 3.5 6.0 4.1 5.7 5.8 5.3 6.8 4.0 5.3 5.7 4.5 4.7 7.2 8.4 4.0 6.7 5.6 3.1 7.5 4.3 8.7 11.5 10.2 15.1 8.3 10.3 10.4 10.4 11.2 10.0 9.8 17.7 11.2 12.8 13.1 8.8 16.0 32.2 11.0 7.2 20.5 12.7 23.8 15.0 15.6 8.6 11.3 5.5 14.6 5.8 20.5 7.7 9.8 5.1 8.6 12.0 13.2 11.5 18.0 12.4 10.9 5.3 5.7 15.6 7.7 20.7 17.1 11.3 9.7 15.7 6.5 11.8 13.0 9.2 4.1 10.6 11.4 3.7 13.4 11.0 16.0 17.8 8.9 9.0 17.5 13.0 30.9 4.7 4.9 10.5 14.2 16.1 7.4 11.4 10.9 14.1 13.1 14.3 11.6 22.8 22.3 20.4 32.4 14.4 19.3 7.0 6.7 11.9 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;placenta: 7.0" "Cell type enhanced" "Detected in some" "dendritic cells: 8.4;Excitatory neurons: 22.5;Inhibitory neurons: 16.6;T-cells: 12.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Region enhanced" "Detected in many" "hippocampal formation: 4.5" "Immune cell enhanced" "Detected in many" "NK-cell: 21.3" "Group enriched" "Detected in many" 35 "NK-cells: 21.3;T-cells: 6.0" "Group enriched" "Detected in some" 9 "HMC-1: 4.6;SCLC-21H: 6.8;SK-MEL-30: 18.4;THP-1: 13.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" 1.9 0.3 1.2 1.2 1.6 0.8 0.4 0.0 2.3 0.6 0.0 0.4 0.3 0.2 0.3 0.8 0.1 0.5 0.2 4.5 0.0 0.3 0.8 0.4 1.8 0.0 0.7 0.2 2.6 0.8 0.0 7.0 0.0 0.1 0.4 0.1 1.3 0.7 3.5 1.4 0.4 0.4 0.0 1.4 0.3 1.0 0.3 1.0 0.1 0.7 0.9 0.7 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 1.2 0.6 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.1 18.4 0.0 0.0 13.4 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 6.0 0.0 3.2 0.0 1.6 1.0 0.0 0.0 0.0 0.1 0.3 21.3 0.0 0.0 3.9 1.2 1.2 1.6 0.0 2.3 4.5 0.0 0.0 0.7 0.0 0.0 0.3 0.7 0.2 0.0 2.3 1.0 0.6 0.5 0.2 0.1 0.6 0.0 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 1.5 0.3 0.3 0.1 0.0 0.8 22.5 0.0 0.0 0.9 2.6 0.7 0.0 1.5 0.0 0.0 3.8 0.0 16.6 0.0 0.0 0.8 0.9 0.9 0.0 0.5 1.8 2.8 0.0 0.0 4.1 1.0 1.6 0.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.0 0.6 0.0 12.8 0.0 0.0 0.1 IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 24.3" "Cell type enhanced" "Detected in some" "Early spermatids: 96.7;Late spermatids: 200.7;Spermatocytes: 44.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 187 "HDLM-2: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA042421 Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 40000 "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042421: AB_10795504" "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" 0.3 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 96.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 200.7 2.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.5 44.4 1.2 0.0 0.6 0.0 14.7 0.0 0.0 0.0 IL13RA2 "CD213a2, CT19, IL-13R, IL13BP" ENSG00000123496 "Interleukin 13 receptor subunit alpha 2" Q14627 X 115003975-115019977 "Cancer-related genes, CD markers, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 12.0;testis: 30.0" "Cell type enriched" "Detected in some" 5 "Early spermatids: 322.4" "Cancer enhanced" "Detected in many" "glioma: 17.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "PC-3: 133.0;U-2197: 425.6;U-251 MG: 297.4;U-87 MG: 167.9" "Region enhanced" "Detected in many" "olfactory bulb: 7.0" "Low region specificity" "Detected in some" "HPA045831, HPA067363" Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "Nucleoplasm, Vesicles" "HPA045831: , HPA067363: " "unprognostic (1.97e-1)" "unprognostic (2.83e-1)" "unprognostic (6.62e-4)" "unprognostic (7.39e-2)" "unprognostic (8.45e-2)" "unprognostic (1.80e-1)" "prognostic favorable (3.55e-4)" "unprognostic (3.54e-1)" "unprognostic (2.85e-1)" "unprognostic (1.92e-2)" "unprognostic (2.20e-3)" "unprognostic (2.19e-2)" "unprognostic (1.53e-5)" "unprognostic (1.58e-1)" "unprognostic (1.63e-1)" "unprognostic (9.70e-3)" "unprognostic (1.20e-1)" 0.8 4.8 1.3 4.0 1.9 0.0 0.4 0.1 1.1 1.1 1.6 0.4 0.3 0.8 4.4 0.6 0.1 0.8 0.7 1.5 10.6 3.6 10.0 1.4 0.1 3.1 3.7 0.1 0.1 0.5 12.0 0.4 1.8 4.1 0.7 0.0 0.9 3.5 0.0 0.2 0.3 0.3 0.7 0.2 0.1 30.0 6.1 2.1 1.2 0.1 0.1 4.4 0.2 0.8 0.4 0.0 4.6 0.1 0.7 3.6 0.0 29.2 28.0 0.1 0.1 0.0 0.0 0.0 0.5 14.6 46.6 0.1 0.0 5.2 0.0 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.1 4.8 0.8 4.6 26.9 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.1 133.0 0.0 0.0 0.0 2.4 0.2 0.0 6.8 2.1 0.3 0.4 0.0 0.1 0.4 0.0 14.7 0.4 425.6 297.4 0.0 0.2 0.1 167.9 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.9 0.1 1.1 1.5 10.6 3.1 3.7 1.8 0.7 6.1 0.8 0.3 0.0 0.0 0.0 0.1 0.1 4.7 0.3 0.0 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 322.4 0.4 0.3 1.3 4.2 0.0 0.4 0.0 0.0 10.3 0.0 0.4 0.0 0.0 46.4 0.4 0.0 0.0 0.6 0.0 0.0 2.8 0.3 58.6 2.8 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.2 8.5 0.0 4.9 0.1 10.9 0.0 0.0 2.9 0.0 0.0 0.0 3.4 63.1 4.0 0.0 0.0 0.0 0.1 0.0 0.0 2.3 IL16 "FLJ16806, FLJ42735, HsT19289, IL-16, LCF, prIL-16" ENSG00000172349 "Interleukin 16" Q14005 15 81159575-81314058 "Cancer-related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Chemotaxis, Host-virus interaction, Transcription, Transcription regulation" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 135.3" "Cell type enhanced" "Detected in many" "B-cells: 135.3;dendritic cells: 78.1;Kupffer cells: 59.2;Langerhans cells: 94.4;NK-cells: 121.5;Plasma cells: 55.6;T-cells: 76.3" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 57.3" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 27.7;HEL: 29.4;HMC-1: 50.6;RPMI-8226: 51.0;U-266/70: 60.3;U-698: 25.8;U-937: 35.1" "Group enriched" "Detected in all" 11 "cerebellum: 54.5;hippocampal formation: 27.0" "Region enriched" "Detected in many" 12 "cerebellum: 48.8" "CAB005247, HPA018467, HPA048861" Enhanced Supported "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 208000 7300 "Cluster 5: Granulocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nuclear speckles" "Plasma membrane, Cytosol" "CAB005247: AB_2124730, HPA018467: AB_1851642, HPA048861: " "unprognostic (8.23e-3)" "unprognostic (2.70e-3)" "unprognostic (1.97e-2)" "unprognostic (9.61e-4)" "unprognostic (2.01e-1)" "unprognostic (5.26e-4)" "unprognostic (2.63e-2)" "unprognostic (6.72e-3)" "unprognostic (2.25e-1)" "unprognostic (3.91e-1)" "unprognostic (1.47e-1)" "unprognostic (6.21e-2)" "unprognostic (3.16e-3)" "unprognostic (1.21e-1)" "unprognostic (3.23e-2)" "unprognostic (5.26e-2)" "unprognostic (1.29e-1)" 18.9 6.3 3.5 63.3 3.0 62.1 15.5 57.3 4.1 9.6 13.8 14.4 11.3 9.9 7.7 7.4 17.8 16.2 5.9 2.9 5.7 3.2 9.7 23.7 132.6 5.9 5.7 6.1 2.6 2.3 2.1 9.0 10.5 5.8 16.8 0.5 11.2 4.5 3.3 12.0 39.9 9.8 5.8 86.2 15.6 4.2 5.2 130.4 6.9 8.5 135.3 18.9 10.4 7.6 0.0 0.0 0.0 0.1 17.5 7.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 27.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.4 0.0 29.4 0.0 0.0 0.9 21.0 50.6 0.9 0.0 0.1 0.6 0.0 0.4 3.5 3.2 10.7 0.1 0.0 1.7 22.2 0.0 0.1 0.0 0.1 0.1 51.0 0.0 0.2 0.1 0.1 0.1 0.0 9.9 0.0 0.0 4.6 0.2 0.3 0.2 1.0 0.0 60.3 5.5 25.8 1.8 35.1 1.5 252.8 116.2 321.3 164.5 142.7 185.9 166.0 170.6 180.6 150.9 157.2 224.9 185.6 282.5 213.2 149.1 113.7 197.0 338.0 3.5 3.0 57.3 4.1 2.9 5.7 5.9 5.7 10.5 5.8 5.2 7.6 9.4 3.2 6.6 0.0 135.3 8.2 0.2 0.8 1.2 0.2 0.8 1.4 2.7 8.6 1.9 1.8 0.0 0.3 78.1 0.3 0.0 0.1 1.4 3.1 6.6 7.5 0.0 20.2 3.4 0.2 0.3 15.9 1.1 0.7 27.1 0.0 26.7 9.2 19.0 0.0 4.9 0.3 0.0 59.2 94.4 1.4 10.8 33.1 28.4 18.7 30.2 0.3 121.5 0.0 0.3 0.0 1.2 18.0 55.6 0.1 0.1 0.4 7.7 0.7 6.6 1.1 3.2 2.1 7.5 1.2 3.7 0.4 76.3 0.2 0.7 0.2 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL1R1 "CD121A, D2S1473, IL1R, IL1RA" ENSG00000115594 "Interleukin 1 receptor type 1" P14778 2 102064544-102179874 "Cancer-related genes, CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Inflammatory response" "Hydrolase, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 127.1;Endometrial stromal cells: 280.2;Glandular and luminal cells: 315.4;Hepatic stellate cells: 146.7;Langerhans cells: 188.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 624.9;ASC TERT1: 276.8;HHSteC: 196.3;HSkMC: 770.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA001237, HPA005823, CAB007779, HPA029560" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1400000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Vesicles" "Plasma membrane, Cytosol" "CAB007779: AB_562073, HPA001237: , HPA005823: AB_2667445, HPA029560: AB_2673094" "unprognostic (6.16e-3)" "unprognostic (3.55e-2)" "unprognostic (3.33e-1)" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (7.10e-2)" "unprognostic (2.01e-1)" "unprognostic (3.36e-2)" "unprognostic (1.44e-1)" "unprognostic (3.16e-1)" "unprognostic (4.26e-2)" "unprognostic (7.77e-2)" "prognostic unfavorable (6.92e-6)" "unprognostic (2.48e-2)" "unprognostic (6.95e-2)" "unprognostic (4.83e-2)" "unprognostic (7.73e-2)" 137.3 68.0 7.1 69.5 8.3 18.0 77.5 7.5 11.0 161.1 16.2 39.3 20.7 33.5 105.2 32.1 52.0 92.0 58.3 7.6 9.0 45.7 75.5 115.5 17.1 16.2 8.4 31.1 43.3 126.7 13.1 120.8 8.9 66.7 30.5 8.5 34.2 47.4 18.6 40.1 40.3 49.9 10.0 41.0 43.9 20.6 14.9 21.7 52.5 16.0 19.7 87.4 40.2 7.7 2.0 12.8 0.3 10.8 624.9 276.8 4.4 27.4 123.8 19.2 28.7 5.7 3.4 0.0 19.8 55.0 33.9 5.5 0.2 2.2 16.1 55.5 0.1 0.7 2.9 31.3 196.3 0.1 0.3 770.6 2.3 21.7 5.2 8.4 8.7 0.0 3.5 1.1 28.1 5.6 0.0 1.2 0.7 5.6 0.9 0.3 2.0 0.4 18.3 13.4 0.1 0.3 12.5 7.7 0.0 3.6 11.1 0.8 0.3 54.7 3.6 92.1 2.2 0.1 0.0 0.1 21.3 0.6 3.6 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.2 0.0 0.0 0.6 0.0 7.1 8.3 7.5 11.0 7.6 9.0 16.2 8.4 8.9 10.0 14.9 7.7 99.3 25.6 73.2 1.3 1.8 31.1 46.8 8.2 5.2 0.1 19.4 13.7 5.2 28.6 68.6 5.5 0.0 6.1 2.5 0.7 3.9 31.7 7.0 127.1 280.2 103.6 1.2 14.3 0.5 21.8 82.8 79.1 2.0 315.4 1.3 0.3 146.7 47.1 5.4 0.0 3.0 0.5 10.2 12.0 188.2 12.6 28.0 26.0 19.6 23.4 7.0 9.0 0.0 0.5 0.5 12.0 0.3 1.5 1.8 65.9 0.0 8.3 28.6 1.0 6.6 37.7 34.3 1.3 1.2 4.5 38.6 23.9 8.5 4.0 0.8 23.6 IL1RL1 "DER4, FIT-1, IL33R, ST2, ST2L, ST2V, T1" ENSG00000115602 "Interleukin 1 receptor like 1" Q01638 2 102311502-102352037 "Candidate cardiovascular disease genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Hydrolase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "kidney: 126.4;lung: 162.0;placenta: 199.8" "Cell type enriched" "Detected in many" 9 "granulocytes: 501.5" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 7.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 64 "basophil: 38.3;eosinophil: 29.3" "Lineage enriched" "Detected in single" 72 "granulocytes: 38.3" "Group enriched" "Detected in some" 6 "HHSteC: 245.1;HMC-1: 373.7;HUVEC TERT2: 185.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007406, HPA007917" Uncertain Supported "Plasma membrane,Focal adhesion sites,Cytosol" "Secreted to blood" NA NA 19100000 3100000 "Cluster 2: Granulocytes - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "Focal adhesion sites, Cytosol" "HPA007406: AB_1079128, HPA007917: AB_1079129" "unprognostic (7.25e-2)" "unprognostic (9.72e-2)" "unprognostic (1.44e-1)" "unprognostic (3.28e-2)" "unprognostic (5.28e-2)" "unprognostic (1.98e-2)" "unprognostic (3.25e-3)" "unprognostic (2.07e-1)" "unprognostic (2.77e-1)" "unprognostic (4.50e-2)" "unprognostic (8.58e-2)" "unprognostic (9.74e-2)" "unprognostic (1.44e-1)" "unprognostic (1.32e-2)" "unprognostic (1.60e-2)" "unprognostic (1.17e-1)" "unprognostic (4.60e-3)" 22.3 30.3 7.5 3.1 9.8 0.7 14.7 7.8 11.0 3.6 12.2 5.2 1.7 2.5 0.6 4.4 2.6 14.7 24.7 7.2 8.2 126.4 16.0 162.0 0.7 7.6 7.7 1.1 4.8 0.8 5.7 199.8 7.7 4.9 3.4 2.8 1.8 4.6 2.5 4.3 8.0 3.7 8.0 1.4 25.1 0.5 9.6 1.3 4.1 0.7 0.8 6.5 3.9 8.9 0.9 0.2 0.7 0.1 15.1 0.6 0.3 0.5 0.7 0.4 0.6 0.3 0.5 0.5 0.7 0.2 0.2 1.4 0.2 6.3 0.4 0.2 0.1 45.7 0.8 0.8 245.1 1.9 373.7 5.1 1.5 6.2 40.0 0.6 185.5 0.2 0.9 0.8 0.7 0.4 0.6 8.7 0.3 0.4 0.7 0.3 0.2 0.2 1.0 0.3 0.6 0.4 0.5 0.3 0.2 0.4 0.3 0.1 15.4 0.5 0.5 3.5 0.5 0.1 0.3 0.4 0.7 0.6 0.5 38.3 0.0 29.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 7.5 9.8 7.8 11.0 7.2 8.2 7.6 7.7 7.7 8.0 9.6 8.9 22.6 9.6 13.1 0.0 0.1 8.5 20.3 0.4 0.0 0.0 0.3 0.1 2.7 0.0 7.7 1.8 0.0 0.0 3.3 0.1 0.0 3.2 0.4 1.1 14.8 49.7 0.0 1.3 0.2 0.5 0.1 54.5 0.0 2.5 501.5 0.0 26.4 0.7 0.0 0.0 0.2 0.0 0.0 0.3 19.1 1.3 0.9 3.0 3.6 0.0 0.0 0.0 0.0 0.5 0.1 37.2 0.0 0.0 3.2 15.7 0.0 0.0 6.6 0.3 39.5 1.5 37.7 0.0 0.0 0.0 5.1 0.0 31.5 0.0 0.0 16.4 IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 21.8;Langerhans cells: 11.4;NK-cells: 23.7;Plasma cells: 13.4;T-cells: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 25.9;HDLM-2: 110.8;Karpas-707: 49.3;RH-30: 37.2;RPMI-8226: 63.0;U-266/70: 24.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" 0.5 0.4 1.4 11.9 1.0 7.6 0.2 1.1 2.6 0.2 0.9 0.8 0.6 0.3 0.2 0.3 0.2 1.1 0.7 0.9 2.3 0.9 0.4 2.9 24.7 2.1 2.3 0.2 0.3 0.0 0.5 0.8 3.3 0.4 0.9 1.1 0.6 0.1 0.3 0.8 2.1 0.7 1.2 5.5 1.5 1.1 1.2 14.4 0.6 0.0 18.8 2.2 0.2 1.6 0.1 0.2 0.3 0.2 0.0 1.3 0.8 0.8 0.1 0.1 2.2 0.2 0.2 25.9 0.2 2.1 1.4 0.1 0.0 0.1 0.1 110.8 0.1 5.4 0.2 0.7 3.4 0.2 1.5 3.8 0.0 6.8 0.1 0.7 0.0 0.6 0.3 49.3 3.8 0.2 0.1 0.5 0.9 0.1 0.0 0.4 37.2 63.0 0.0 0.1 0.2 0.2 0.1 0.1 2.7 0.2 0.1 1.3 2.8 1.9 0.7 0.6 0.2 24.7 9.4 5.9 5.2 1.4 0.2 0.5 0.4 0.1 13.4 8.3 4.9 1.8 8.6 14.2 2.3 14.2 9.2 9.3 0.9 9.5 27.0 1.1 10.8 7.3 1.4 1.0 1.1 2.6 0.9 2.3 2.1 2.3 3.3 1.2 1.2 1.6 0.2 0.0 1.3 0.0 15.5 0.4 0.1 0.0 0.0 2.0 0.2 0.1 1.9 0.0 0.0 0.0 4.2 0.1 21.8 0.1 0.0 0.0 6.5 0.1 0.2 0.9 0.0 0.0 0.4 0.0 0.1 0.3 1.5 0.2 0.0 0.0 1.1 0.2 8.2 0.0 0.5 0.0 0.0 5.0 11.4 5.7 0.0 3.6 1.8 2.8 1.8 0.2 23.7 0.5 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.0 0.5 0.0 0.8 0.8 0.2 0.0 0.0 0.9 0.1 25.1 0.1 0.1 0.1 IL36G "IL-1F9, IL-1H1, IL-1RP2, IL1E, IL1F9, IL1H1" ENSG00000136688 "Interleukin 36 gamma" Q9NZH8 2 112973203-112985658 "Predicted intracellular proteins, Predicted secreted proteins" "Immunity, Inflammatory response, Innate immunity" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "esophagus: 14.3;lymphoid tissue: 39.4;skin 1: 31.3" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 136.0;Club cells: 36.0" "Cancer enhanced" "Detected in some" "head and neck cancer: 36.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.1;HaCaT: 1.0" "Not detected" "Not detected" HPA068168 Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 11000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 12: NES - Nervous system development" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Nucleoplasm, Plasma membrane" "HPA068168: " "unprognostic (1.56e-2)" "unprognostic (2.88e-1)" "unprognostic (7.27e-2)" "unprognostic (3.15e-2)" "unprognostic (4.91e-2)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (3.68e-1)" "unprognostic (2.18e-1)" "unprognostic (1.32e-1)" "unprognostic (2.01e-2)" "unprognostic (5.79e-2)" "unprognostic (5.58e-2)" "unprognostic (1.06e-1)" 0.0 0.0 0.0 0.0 0.0 0.2 1.1 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 3.9 0.2 0.0 31.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 39.4 0.8 3.6 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.2 0.0 1.1 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.3 136.0 0.0 0.0 0.0 0.0 0.0 0.0 36.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.1 0.0 0.7 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 3.9 0.0 0.0 0.0 1.3 0.2 0.0 1.7 13.2 0.0 0.0 0.0 0.0 7.8 IL4R CD124 ENSG00000077238 "Interleukin 4 receptor" P24394 16 27313668-27364778 "Cancer-related genes, CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" Immunity Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 92.0;granulocytes: 110.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "naive B-cell: 78.1" "Group enriched" "Detected in all" 5 "B-cells: 78.1;granulocytes: 31.1" "Cell line enhanced" "Detected in many" "Daudi: 124.2;HBEC3-KT: 115.0;HDLM-2: 110.6;U-698: 119.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004451, HPA050124, HPA070380" Enhanced Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 38500 110000 "Cluster 37: B-cells - Transcription" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "Centriolar satellite" "CAB004451: AB_626889, HPA050124: AB_2681026, HPA070380: " "unprognostic (6.80e-2)" "unprognostic (6.35e-2)" "unprognostic (2.84e-1)" "prognostic favorable (6.43e-4)" "unprognostic (1.12e-1)" "unprognostic (1.14e-1)" "unprognostic (2.33e-2)" "unprognostic (1.95e-3)" "unprognostic (1.34e-1)" "unprognostic (1.54e-1)" "unprognostic (2.41e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (1.49e-2)" "unprognostic (1.73e-1)" "unprognostic (1.36e-1)" "unprognostic (9.58e-2)" 49.4 45.2 22.7 82.3 19.7 103.4 34.1 19.2 22.0 39.7 21.4 97.0 27.3 35.8 5.9 70.8 42.3 41.2 34.2 18.7 21.0 50.8 116.0 119.2 117.1 29.4 22.2 14.3 29.8 31.7 14.9 39.3 24.0 49.9 35.6 2.4 20.5 25.6 9.3 24.4 55.7 37.3 25.5 90.0 55.0 15.5 25.3 22.3 24.2 6.6 89.6 63.2 45.4 23.8 39.9 10.1 6.4 13.1 3.1 14.1 14.3 24.7 27.3 9.3 7.7 20.4 105.2 124.2 30.1 38.5 18.3 39.7 7.3 115.0 8.2 110.6 4.0 22.6 6.6 31.6 40.8 6.1 61.7 23.5 45.0 44.2 26.5 48.7 50.7 6.8 10.5 9.8 15.0 17.3 0.7 18.8 8.0 34.2 9.1 0.4 47.5 10.2 42.9 43.2 1.9 0.6 3.7 24.7 5.0 15.6 8.2 23.5 81.0 21.0 9.8 19.0 17.6 6.1 2.1 119.7 2.1 21.1 0.3 1.4 7.2 13.0 4.2 3.1 3.4 25.8 6.9 4.4 4.1 78.1 10.0 5.0 31.1 8.2 1.8 4.8 5.3 5.8 22.7 19.7 19.2 22.0 18.7 21.0 29.4 22.2 24.0 25.5 25.3 23.8 30.5 28.9 49.2 0.7 92.0 13.3 43.3 34.9 26.2 0.3 9.4 14.2 2.4 34.3 33.4 1.8 0.0 17.6 29.8 60.0 0.0 39.5 0.3 6.6 2.2 39.0 23.4 5.2 1.7 32.3 3.8 17.2 32.1 17.2 110.8 0.7 62.8 45.9 27.2 0.0 0.6 35.5 8.2 30.6 29.9 0.8 0.3 34.3 14.2 38.4 39.3 0.0 7.2 0.5 0.7 49.3 28.7 0.0 13.4 37.7 24.0 1.2 28.5 0.2 39.5 16.4 20.0 0.8 3.3 23.8 14.9 24.9 38.3 0.2 16.7 46.9 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;retina: 10.6;testis: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 22.9;Excitatory neurons: 45.0;Muller glia cells: 89.1;Oligodendrocyte precursor cells: 96.0" "Cancer enriched" "Detected in some" 5 "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;JURKAT: 5.7;MOLT-4: 4.3;U-2 OS: 9.6;U-251 MG: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 0.3 0.3 7.0 0.2 6.7 0.5 0.0 0.0 8.0 0.1 0.0 1.6 0.1 0.1 0.4 0.1 0.2 0.3 1.4 8.7 4.4 2.8 0.4 0.4 0.2 0.0 4.8 0.1 0.1 0.0 1.4 0.1 0.2 0.8 0.3 10.6 0.1 1.1 0.1 0.0 0.2 0.7 0.0 0.1 0.1 8.8 12.8 1.1 0.1 0.2 0.2 0.3 0.1 1.5 0.0 0.0 7.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.8 1.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.2 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 4.3 0.0 2.7 0.1 0.0 0.0 0.2 0.5 0.5 0.1 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 9.6 0.0 5.4 1.8 0.0 0.4 1.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 6.7 0.0 8.0 8.7 4.4 0.0 4.8 0.2 0.0 12.8 1.5 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 4.3 0.0 0.6 0.0 6.2 0.0 2.0 0.2 0.0 0.1 12.7 0.0 0.1 0.2 1.2 0.0 45.0 0.2 0.3 0.6 0.0 0.1 0.0 1.7 0.4 1.6 0.1 1.7 17.6 0.0 0.0 0.0 0.0 18.8 0.6 0.2 0.0 5.6 0.6 89.1 0.0 96.0 16.5 0.1 0.2 0.0 0.9 0.0 0.0 4.9 0.0 8.8 0.0 8.8 0.5 4.8 2.0 0.0 0.0 0.3 0.5 0.1 0.3 0.0 ILK ENSG00000166333 "Integrin linked kinase" Q13418 11 6603708-6610874 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004041, HPA048437" Enhanced Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 30000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Focal adhesion sites" Nucleoplasm "CAB004041: AB_2127050, HPA048437: AB_2680391" "unprognostic (1.78e-1)" "unprognostic (2.26e-2)" "unprognostic (5.26e-2)" "unprognostic (2.12e-2)" "unprognostic (7.57e-2)" "unprognostic (1.01e-1)" "unprognostic (6.19e-3)" "unprognostic (5.25e-3)" "unprognostic (1.49e-2)" "unprognostic (9.65e-2)" "unprognostic (2.64e-1)" "unprognostic (8.12e-2)" "prognostic favorable (2.44e-4)" "unprognostic (4.01e-3)" "unprognostic (9.27e-2)" "unprognostic (2.42e-1)" "unprognostic (6.36e-3)" 108.0 77.2 49.8 85.1 52.4 43.7 91.8 51.7 50.6 151.6 55.0 398.2 66.4 359.1 81.8 115.5 164.2 88.0 175.9 47.4 50.7 78.8 65.9 107.9 72.4 51.8 50.6 101.0 89.3 73.2 47.1 98.8 50.9 182.7 116.8 28.3 69.5 412.2 90.8 61.5 117.4 364.7 51.1 95.5 149.7 26.5 53.7 45.8 72.0 92.0 70.5 226.7 118.8 51.9 127.8 94.4 148.9 51.8 224.8 159.4 67.2 182.2 360.0 211.9 256.0 102.7 145.7 47.0 47.0 304.1 206.9 99.5 84.4 155.6 213.0 83.5 74.3 69.1 84.9 82.8 150.8 55.9 74.7 153.2 72.8 143.8 108.9 217.7 206.9 40.5 63.7 55.0 282.8 97.1 49.4 97.4 94.3 107.5 110.8 51.0 77.8 50.5 160.3 100.8 25.6 57.4 86.0 118.4 103.6 144.0 82.2 62.2 238.8 263.9 118.0 111.1 90.7 38.9 25.9 67.1 195.6 82.8 125.3 314.9 260.0 417.6 127.3 258.1 124.9 96.9 114.4 122.3 242.7 92.9 70.2 88.5 165.5 257.8 254.8 98.5 142.8 402.8 49.8 52.4 51.7 50.6 47.4 50.7 51.8 50.6 50.9 51.1 53.7 51.9 79.5 44.8 17.9 24.2 33.6 50.5 73.7 100.6 24.5 21.5 43.1 68.2 0.5 70.1 49.7 57.0 8.4 119.8 46.0 71.9 58.7 136.1 64.6 33.2 78.1 69.4 37.9 53.7 14.6 125.0 177.7 83.2 50.4 52.5 30.4 41.6 76.4 31.4 127.4 8.4 17.1 50.1 69.2 51.5 97.7 143.7 71.4 115.9 85.4 30.9 143.0 54.3 77.2 15.6 15.3 117.1 60.0 147.4 35.1 42.0 74.5 98.6 31.0 32.9 157.8 53.3 165.8 31.7 17.1 32.3 43.2 110.0 49.3 65.0 50.1 43.9 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 6.7" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 22.5 16.9 26.8 12.0 85.5 9.5 17.3 56.9 30.4 29.6 10.9 54.2 19.2 49.5 19.5 29.6 30.7 15.2 75.0 20.4 21.3 14.1 14.6 25.1 8.4 20.5 37.7 19.5 12.8 12.2 14.7 28.8 20.4 24.5 16.7 16.9 13.5 23.6 75.4 22.9 23.4 42.1 17.5 13.9 27.6 22.9 50.5 6.8 14.1 50.3 7.3 35.5 22.7 27.0 35.4 13.7 22.6 21.9 33.8 23.7 18.4 36.4 27.9 23.3 15.4 32.6 14.0 3.1 13.7 38.8 15.1 19.5 24.8 15.2 27.9 10.8 14.4 5.1 17.3 44.7 24.3 12.9 11.9 16.0 14.9 15.0 28.2 18.6 16.3 6.6 7.6 18.2 12.6 28.3 3.6 40.9 10.5 21.0 24.3 7.6 14.9 5.6 19.4 19.9 5.4 18.5 18.3 26.5 22.6 20.5 17.2 30.4 13.7 14.9 17.2 20.1 21.6 3.6 18.4 11.0 14.4 8.6 6.5 6.7 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.3 26.8 85.5 56.9 30.4 20.4 21.3 20.5 37.7 20.4 17.5 50.5 27.0 14.7 9.6 19.7 14.7 4.5 5.4 4.4 1.9 0.0 10.5 7.1 5.3 10.1 4.3 6.4 7.3 0.0 3.9 5.0 24.8 0.0 6.5 12.3 2.8 22.8 10.0 6.1 3.2 33.5 9.2 3.7 5.6 6.6 5.9 8.8 8.6 15.0 17.9 2.9 8.4 25.2 9.9 2.0 7.2 12.0 17.0 7.2 6.9 1.8 19.7 4.1 9.6 0.0 18.1 29.2 12.1 11.5 11.7 2.5 6.5 13.8 4.3 2.5 5.2 6.6 6.5 24.3 6.3 7.3 2.8 5.8 2.5 2.7 10.7 13.9 8.6 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 INTS12 "INT12, PHF22, SBBI22" ENSG00000138785 "Integrator complex subunit 12" Q96CB8 4 105682627-105895986 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035772, HPA041814" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Nuclear bodies, Plasma membrane" "HPA035772: AB_10671109, HPA041814: AB_2677687" "unprognostic (5.30e-2)" "unprognostic (4.54e-2)" "unprognostic (1.84e-3)" "unprognostic (1.78e-1)" "unprognostic (3.68e-2)" "unprognostic (2.58e-3)" "prognostic unfavorable (2.67e-4)" "unprognostic (3.95e-2)" "unprognostic (1.13e-1)" "unprognostic (1.53e-3)" "unprognostic (3.00e-2)" "unprognostic (3.48e-2)" "unprognostic (5.93e-3)" "unprognostic (3.62e-1)" "unprognostic (1.37e-1)" "unprognostic (2.16e-2)" "unprognostic (2.06e-1)" 15.2 11.1 12.8 10.9 13.3 30.4 20.2 14.9 18.0 14.1 12.0 14.7 18.1 14.6 17.8 13.5 13.2 12.7 18.9 12.4 14.9 18.7 22.6 16.4 14.0 12.3 14.0 11.6 12.6 17.2 10.3 11.9 12.5 18.1 15.6 17.2 14.4 13.4 26.5 14.0 15.5 17.1 12.7 12.6 15.0 13.9 14.3 19.9 19.9 26.0 17.0 15.6 11.2 13.7 24.4 12.8 28.5 29.8 27.5 32.6 20.8 28.2 29.1 34.7 35.9 18.1 26.9 34.9 15.4 31.9 26.9 13.8 31.7 40.7 42.8 36.9 19.0 26.3 19.6 25.7 44.3 46.7 23.0 31.0 51.7 34.5 51.4 22.5 32.3 29.1 39.8 26.7 37.8 25.6 55.3 28.9 12.4 35.3 19.5 28.0 31.0 26.8 32.5 16.3 30.7 24.6 19.8 32.6 31.0 22.4 26.4 27.2 21.3 22.7 23.3 24.8 30.5 40.8 40.9 52.2 25.3 31.5 46.0 64.0 23.7 38.5 25.7 26.6 28.9 33.0 29.4 29.4 27.7 32.1 30.6 28.3 17.9 42.9 28.3 42.6 34.8 21.9 12.8 13.3 14.9 18.0 12.4 14.9 12.3 14.0 12.5 12.7 14.3 13.7 19.0 12.8 11.8 14.0 15.1 11.0 11.8 25.8 15.4 10.5 12.1 11.7 18.7 11.5 12.9 3.7 10.4 16.1 13.6 8.3 43.0 25.2 35.8 8.1 11.2 16.8 6.0 15.6 13.8 20.3 18.6 10.8 8.6 8.7 24.7 9.9 11.7 9.3 17.8 10.1 15.7 5.2 30.5 9.0 9.5 28.4 12.2 9.8 7.2 9.4 15.5 14.0 21.6 27.2 19.1 20.5 6.8 8.2 18.9 14.2 16.5 17.1 6.2 9.3 0.0 12.9 20.1 13.4 16.2 14.1 10.4 18.3 13.0 14.9 10.2 11.0 IP6K2 IHPK2 ENSG00000068745 "Inositol hexakisphosphate kinase 2" Q9UHH9 3 48688003-48740353 "Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Phospholipid metabolism" "Kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007532, HPA070811" Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 50: Non-specific - Ribosome" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA007532: AB_1851542, HPA070811: AB_2732165" "prognostic favorable (1.25e-4)" "unprognostic (2.55e-2)" "unprognostic (8.86e-2)" "unprognostic (6.69e-3)" "unprognostic (1.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.76e-3)" "prognostic favorable (2.95e-4)" "unprognostic (6.57e-3)" "unprognostic (1.56e-1)" "unprognostic (1.92e-3)" "unprognostic (1.99e-2)" "unprognostic (1.24e-1)" "unprognostic (1.35e-1)" "unprognostic (1.64e-1)" "unprognostic (3.50e-2)" "prognostic favorable (1.83e-4)" 57.6 96.3 53.1 39.5 57.2 130.1 80.1 84.6 57.8 117.2 52.8 106.0 79.8 101.8 108.4 95.4 78.3 47.9 62.3 53.7 58.4 106.9 83.5 55.4 53.7 56.2 53.3 99.1 91.2 48.0 121.8 44.8 55.1 111.6 88.0 63.7 88.7 42.2 45.8 145.4 89.1 43.1 49.7 78.9 79.5 55.5 55.2 72.2 108.8 31.5 43.5 66.7 113.4 64.2 25.9 49.5 100.6 71.2 55.5 69.3 72.6 48.0 54.0 54.0 62.2 41.1 67.0 45.5 38.7 45.5 67.8 65.3 50.6 72.1 50.0 54.1 44.9 52.2 172.7 89.5 45.0 50.3 48.9 65.7 103.0 73.3 59.7 71.8 76.2 143.8 39.5 55.4 63.9 57.3 107.4 68.3 77.4 50.0 90.4 44.4 33.3 50.0 73.7 121.7 62.4 94.6 103.9 69.5 53.0 79.6 67.7 83.3 54.8 58.3 57.4 37.0 48.7 50.6 65.4 64.2 53.3 57.7 52.4 158.1 50.5 92.7 63.4 50.8 57.6 60.8 55.1 60.4 50.1 60.2 51.1 52.7 80.3 67.5 65.3 52.0 84.2 46.8 53.1 57.2 84.6 57.8 53.7 58.4 56.2 53.3 55.1 49.7 55.2 64.2 63.3 70.5 52.9 38.5 41.3 83.1 87.2 182.5 174.2 66.5 69.9 77.5 12.9 38.6 109.1 99.3 39.6 114.3 39.4 157.4 76.3 58.7 43.8 50.8 64.8 46.1 110.2 40.1 31.1 47.4 73.9 73.7 64.2 56.9 54.5 60.3 32.5 25.1 41.4 20.2 40.6 108.6 150.5 16.6 33.5 16.4 81.1 24.5 26.6 22.5 30.3 32.4 44.3 50.8 52.6 60.5 105.7 68.4 34.0 59.0 84.7 65.5 68.4 56.0 52.6 31.5 50.6 71.6 57.9 90.3 83.0 124.0 43.3 87.9 89.8 89.3 IPCEF1 "KIAA0403, PIP3-E" ENSG00000074706 "Interaction protein for cytohesin exchange factors 1" Q8WWN9 6 154154496-154356792 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 17.7;brain: 13.6;lymphoid tissue: 13.5;thyroid gland: 39.1" "Cell type enhanced" "Detected in many" "dendritic cells: 46.1;Excitatory neurons: 120.0;Microglial cells: 252.9;T-cells: 65.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 71.6" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 4 "HMC-1: 19.8;THP-1: 10.5;U-937: 11.0" "Low region specificity" "Detected in all" "HPA028708, HPA028710" Supported Approved "Nucleoli,Nuclear speckles,Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles, Plasma membrane" "Nucleoli, Cytoplasmic bodies" "HPA028708: AB_10601916, HPA028710: AB_2732442" "unprognostic (1.23e-2)" "unprognostic (8.93e-3)" "unprognostic (4.18e-2)" "unprognostic (5.63e-3)" "unprognostic (2.05e-1)" "unprognostic (6.55e-3)" "unprognostic (1.30e-3)" "unprognostic (2.57e-2)" "unprognostic (3.87e-1)" "unprognostic (5.84e-2)" "unprognostic (3.27e-2)" "unprognostic (4.87e-2)" "unprognostic (5.01e-2)" "unprognostic (8.64e-2)" "unprognostic (5.45e-2)" "unprognostic (1.42e-2)" "unprognostic (1.51e-4)" 0.7 0.2 8.4 7.9 5.4 17.7 1.5 4.1 13.6 2.7 0.0 1.3 0.7 1.1 1.4 1.4 2.1 2.9 0.6 5.4 3.2 2.8 2.0 1.5 13.5 0.0 7.4 0.6 0.7 0.1 0.6 1.6 0.0 0.8 1.2 0.2 1.2 0.4 0.2 0.5 2.3 0.9 0.0 6.8 2.4 0.9 12.2 10.6 39.1 0.2 12.8 2.1 0.5 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 1.0 0.0 0.0 0.0 0.1 19.8 0.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 3.1 1.2 0.8 0.0 0.5 0.1 0.1 0.3 0.7 2.1 0.2 0.1 0.0 0.1 0.0 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 11.0 0.0 3.2 14.5 71.6 13.0 6.5 27.6 0.0 16.3 12.5 16.2 0.1 27.9 16.8 42.7 14.3 8.5 0.4 22.6 12.6 8.4 5.4 4.1 13.6 5.4 3.2 0.0 7.4 0.0 0.0 12.2 5.4 1.1 0.0 1.7 7.8 3.5 0.6 0.5 0.4 12.0 0.6 1.8 1.0 1.1 1.5 1.7 1.8 0.0 1.7 46.1 0.0 7.9 2.1 1.3 2.0 1.2 2.3 0.0 3.2 120.0 0.0 0.1 1.0 3.1 2.5 0.0 0.1 3.3 1.1 2.8 3.3 9.8 0.5 2.0 23.4 15.2 0.3 0.3 15.2 0.0 252.9 17.9 0.2 27.8 9.0 14.6 0.0 0.1 0.4 20.7 0.6 0.1 2.0 1.3 0.2 0.0 3.4 0.4 0.2 1.1 4.0 0.6 2.7 65.5 2.0 0.3 1.3 IQGAP1 "HUMORFA01, KIAA0051, p195, SAR1" ENSG00000140575 "IQ motif containing GTPase activating protein 1" P46940 15 90388242-90502239 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013302, HPA014055" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cell Junctions" "CAB013302: AB_2533146, HPA014055: AB_1851856" "unprognostic (2.83e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (5.95e-2)" "unprognostic (4.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.25e-3)" 57.3 31.1 14.4 69.3 30.0 69.7 51.6 19.8 20.5 62.0 26.9 67.1 32.3 72.2 21.3 75.6 45.1 55.0 22.9 17.0 21.5 35.6 18.8 74.2 58.9 29.0 24.6 39.6 30.1 49.7 12.1 79.8 28.1 36.2 66.9 7.1 72.2 38.0 15.0 64.9 37.9 81.3 16.5 57.7 52.6 13.0 27.9 65.4 64.3 25.4 63.4 63.5 31.4 63.4 148.9 81.5 39.8 46.6 99.3 128.4 229.6 139.7 127.0 124.7 132.4 93.6 150.5 82.7 66.2 231.5 111.4 259.2 80.6 153.5 149.5 106.4 56.6 55.5 145.8 34.3 120.2 102.9 113.6 76.2 139.5 147.2 206.5 152.7 172.8 53.0 49.0 112.8 192.3 76.5 55.4 30.8 51.6 235.8 45.6 67.5 106.5 72.1 126.9 233.8 49.5 37.3 195.1 96.9 100.7 162.8 85.1 86.5 224.2 141.1 73.4 120.4 145.6 43.3 67.0 82.4 128.3 98.5 77.5 30.6 27.5 20.0 21.8 25.2 19.3 12.6 13.5 18.9 23.3 12.5 7.9 14.0 89.9 27.6 31.0 13.8 16.1 16.9 14.4 30.0 19.8 20.5 17.0 21.5 29.0 24.6 28.1 16.5 27.9 63.4 180.9 266.0 286.3 36.2 129.2 103.0 124.9 87.7 72.8 4.6 115.1 88.4 18.0 54.3 167.2 77.3 16.7 89.7 215.3 204.5 7.9 95.9 8.8 133.8 127.9 135.7 60.7 46.7 39.7 98.7 159.4 116.5 91.7 242.0 209.3 130.2 95.3 11.6 149.0 1.7 24.4 121.1 63.1 407.5 175.1 13.2 47.8 261.6 71.2 60.9 272.2 13.5 200.8 9.5 316.0 128.1 112.1 48.2 137.3 98.6 72.7 19.6 134.2 30.2 78.9 108.8 131.0 18.9 32.6 99.3 113.4 95.6 176.8 56.0 152.0 151.5 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108334 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 60.3;lymphoid tissue: 202.8" "Cell type enhanced" "Detected in some" "Adipocytes: 13.1;B-cells: 6.2;dendritic cells: 42.9;Hofbauer cells: 14.1;Plasma cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 210.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 634.3;REH: 221.9;U-698: 722.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" 9.6 1.9 8.5 47.2 5.4 60.3 6.5 2.3 5.6 2.4 3.2 10.1 8.7 2.5 2.8 5.2 5.1 7.8 2.4 6.6 2.6 9.4 6.2 7.7 171.7 6.0 4.4 5.7 30.7 1.5 2.4 4.4 6.1 3.4 9.2 1.1 3.6 4.4 1.1 5.8 19.1 4.5 3.6 37.5 10.1 1.0 2.8 95.1 4.9 1.6 202.8 14.5 8.3 4.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 634.3 0.3 0.0 0.0 0.2 0.0 2.4 0.0 22.1 0.0 37.8 0.0 0.1 0.0 49.7 54.2 0.0 0.0 0.7 0.0 0.1 0.0 31.5 7.8 40.6 0.0 0.0 54.5 91.2 0.1 0.0 0.0 221.9 0.3 63.8 0.7 29.7 0.2 0.1 0.2 0.3 0.2 0.1 0.0 36.7 0.5 0.0 1.5 0.0 0.1 40.4 7.8 722.4 0.2 21.8 0.0 80.2 21.0 210.1 23.6 40.8 20.2 66.1 14.9 24.2 22.4 51.0 25.5 25.4 151.3 49.0 51.5 20.8 2.7 20.2 8.5 5.4 2.3 5.6 6.6 2.6 6.0 4.4 6.1 3.6 2.8 4.6 13.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 IREB2 IRP2 ENSG00000136381 "Iron responsive element binding protein 2" P48200 15 78437431-78501453 "Disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" RNA-binding "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032885, HPA040371, HPA068982" Uncertain Approved "Cell Junctions,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Cell Junctions" Cytosol "CAB032885: AB_2126703, HPA040371: AB_2676945, HPA068982: AB_2686064" "unprognostic (1.00e-2)" "unprognostic (1.30e-1)" "unprognostic (6.54e-2)" "unprognostic (3.44e-2)" "unprognostic (3.39e-2)" "unprognostic (2.29e-1)" "unprognostic (2.33e-1)" "unprognostic (1.06e-1)" "unprognostic (7.30e-2)" "unprognostic (1.01e-1)" "unprognostic (1.38e-1)" "unprognostic (6.51e-2)" "unprognostic (3.85e-3)" "unprognostic (4.09e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-2)" "unprognostic (9.40e-2)" 17.1 25.2 7.5 18.2 7.7 27.7 18.8 16.3 9.3 15.2 8.4 17.4 17.9 17.9 11.8 15.2 14.6 14.9 12.5 7.4 10.5 18.3 23.1 14.9 22.8 7.0 7.2 22.0 11.4 17.8 8.2 21.8 7.1 16.5 20.3 19.4 10.6 15.4 18.8 14.4 18.4 16.1 7.0 24.8 16.4 15.1 9.5 29.7 28.7 23.5 20.9 13.4 11.7 8.8 19.9 34.9 52.8 33.2 45.5 29.7 35.5 33.3 26.0 29.7 26.9 34.6 33.8 73.1 22.1 28.0 20.3 37.8 124.7 33.2 26.1 23.4 43.0 63.6 35.0 24.4 23.8 69.4 65.7 31.5 22.4 22.9 27.7 30.2 35.4 42.6 67.9 25.4 25.5 29.7 42.8 35.2 69.1 24.1 12.4 49.6 53.0 20.8 32.4 54.2 31.7 47.3 45.1 31.4 35.7 59.2 29.5 59.7 28.9 30.3 20.8 16.8 29.2 31.5 74.8 41.7 21.8 63.1 22.2 3.8 2.5 2.0 2.4 3.3 3.1 2.7 2.6 2.4 3.5 2.6 2.5 3.5 2.8 3.0 2.6 4.0 2.3 1.4 7.5 7.7 16.3 9.3 7.4 10.5 7.0 7.2 7.1 7.0 9.5 8.8 24.3 22.4 40.7 33.0 37.5 14.1 16.6 19.3 14.8 55.6 23.1 18.4 24.9 25.8 26.1 23.9 66.7 35.0 56.2 45.3 0.0 19.9 18.1 19.3 38.2 26.6 31.9 42.3 52.3 19.6 23.7 27.7 32.1 21.2 17.7 66.2 38.9 41.8 26.1 79.1 55.6 31.0 18.3 61.3 18.4 10.8 32.9 37.7 14.2 28.1 52.9 22.4 54.6 50.3 49.0 26.3 49.8 30.5 28.5 33.7 49.1 19.6 25.7 51.1 6.6 29.5 23.2 33.9 29.6 24.5 18.6 30.6 33.9 56.3 36.0 29.6 IRF2 ENSG00000168310 "Interferon regulatory factor 2" P14316 4 184387729-184474550 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 163.6;Karpas-707: 165.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030813, CAB032306, HPA057327" Supported Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions, Cytosol" "CAB032306: AB_2249157, HPA030813: AB_10600718, HPA057327: AB_2683410" "prognostic favorable (6.95e-5)" "unprognostic (1.69e-3)" "unprognostic (5.43e-2)" "unprognostic (1.59e-3)" "unprognostic (2.70e-2)" "unprognostic (1.46e-1)" "unprognostic (2.48e-2)" "unprognostic (4.05e-2)" "unprognostic (8.37e-3)" "unprognostic (2.90e-2)" "unprognostic (4.00e-2)" "unprognostic (2.35e-1)" "unprognostic (6.87e-3)" "unprognostic (8.55e-3)" "unprognostic (5.25e-2)" "prognostic favorable (8.34e-5)" "unprognostic (1.31e-3)" 25.1 30.1 18.2 47.8 23.4 18.0 21.9 22.1 19.3 25.6 21.4 27.8 31.1 21.8 22.7 26.7 25.3 24.9 19.5 17.5 21.9 18.5 37.4 27.6 62.5 25.3 22.1 28.1 14.8 20.2 12.3 28.9 25.2 20.6 28.7 9.3 29.1 21.2 28.1 19.4 33.3 23.2 21.7 54.9 31.5 6.1 23.5 49.8 21.7 23.8 52.2 35.6 22.5 29.6 20.3 14.9 17.5 12.0 37.4 37.9 10.5 14.4 44.8 34.8 36.0 4.2 37.9 12.2 7.4 21.7 28.4 18.3 12.0 27.4 22.1 163.6 6.6 34.4 7.9 26.8 37.1 21.1 27.7 41.2 24.8 19.8 50.1 29.8 26.7 14.5 6.9 165.3 14.6 14.1 40.6 25.8 4.0 18.5 10.7 52.7 6.9 55.1 26.6 30.4 7.5 11.6 20.4 16.8 31.3 7.3 13.0 18.9 22.0 9.9 10.7 11.3 12.8 47.3 40.6 11.0 20.9 20.3 17.8 106.7 95.7 175.8 76.4 126.3 77.9 104.9 74.5 82.2 79.6 107.7 78.8 78.8 407.6 94.8 145.7 20.2 111.7 100.3 18.2 23.4 22.1 19.3 17.5 21.9 25.3 22.1 25.2 21.7 23.5 29.6 58.9 38.5 24.5 53.5 68.9 49.1 50.5 60.4 45.5 13.1 25.8 27.3 21.9 27.1 36.0 25.8 6.2 31.3 48.8 40.3 37.2 30.9 0.2 53.4 40.2 42.9 30.6 62.7 23.8 30.1 16.2 35.8 34.1 63.2 26.6 23.1 38.2 37.6 48.5 20.2 27.8 29.5 44.7 90.3 53.5 3.0 37.3 65.9 19.6 41.2 144.0 23.4 70.0 43.7 77.1 28.7 38.9 53.0 63.4 72.9 42.1 46.1 58.7 8.4 39.5 25.4 44.8 0.6 2.4 49.5 44.5 26.7 56.3 37.7 22.8 70.9 IRS1 HIRS-1 ENSG00000169047 "Insulin receptor substrate 1" P35568 2 226731312-226799820 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Transducer "Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.4;Theca cells: 110.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005261, HPA046433" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005261: AB_649615, HPA046433: AB_2732524" "unprognostic (2.20e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.59e-2)" "unprognostic (3.86e-3)" "unprognostic (1.61e-1)" "unprognostic (1.44e-1)" "unprognostic (1.80e-3)" "unprognostic (5.47e-2)" "unprognostic (2.24e-2)" "unprognostic (5.48e-3)" "unprognostic (1.10e-1)" "unprognostic (1.36e-3)" "unprognostic (1.46e-2)" "unprognostic (6.92e-2)" "unprognostic (3.23e-2)" "unprognostic (7.55e-3)" 7.6 9.7 1.7 2.9 1.6 0.5 11.7 5.2 3.1 14.7 1.8 10.3 3.9 17.4 1.9 3.6 15.0 5.6 5.0 1.6 1.0 3.4 10.5 5.0 1.7 1.8 1.6 20.9 3.5 3.3 1.5 9.5 1.2 7.8 2.7 1.5 3.0 7.0 28.0 5.2 5.1 10.3 2.0 2.0 5.3 0.8 1.6 8.1 20.0 2.9 1.3 11.6 6.6 1.5 5.7 26.0 18.6 0.7 25.0 14.8 0.0 15.6 12.2 20.4 13.0 15.0 14.4 2.3 2.5 10.6 14.0 10.0 1.2 15.0 11.5 5.9 1.0 0.1 1.7 7.1 12.5 0.5 0.1 20.7 8.1 16.1 14.5 12.3 0.0 2.3 3.0 22.7 14.0 22.6 4.9 6.6 7.5 3.6 14.3 1.1 24.1 0.1 9.3 18.9 3.2 0.5 5.0 3.6 8.4 14.9 13.7 0.3 1.3 26.8 24.2 20.9 15.1 10.6 4.6 3.4 26.5 0.5 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.6 5.2 3.1 1.6 1.0 1.8 1.6 1.2 2.0 1.6 1.5 1.7 19.2 4.6 5.9 2.7 35.4 31.9 29.7 19.4 19.3 36.9 28.1 13.4 14.3 12.8 0.0 0.0 6.4 0.0 13.2 17.6 15.4 1.6 22.1 28.4 2.1 2.4 0.0 17.3 11.4 0.6 28.3 2.0 24.3 0.0 75.4 1.8 57.4 1.7 20.2 31.3 6.5 24.4 1.3 4.6 1.8 22.7 3.6 16.0 15.0 0.8 8.4 0.0 26.7 1.7 11.1 8.2 14.7 9.5 14.5 23.4 3.0 8.1 1.7 13.1 9.5 22.8 1.0 1.2 4.2 23.7 18.3 1.2 110.3 7.7 22.8 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.6;epididymis: 10.7;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 16.1;Erythroid cells: 43.5;granulocytes: 17.8;Late spermatids: 24.8;Macrophages: 23.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 64.5" "Lineage enriched" "Detected in single" 75 "granulocytes: 64.5" "Group enriched" "Detected in some" 14 "HEL: 404.6;HMC-1: 631.7" "Not detected" "Not detected" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" 0.8 0.2 3.7 0.2 3.6 16.6 0.4 4.0 4.8 1.5 3.8 0.3 0.0 0.9 10.7 0.3 1.5 0.8 1.4 3.5 3.6 1.0 0.5 5.1 0.2 3.6 3.5 1.5 0.1 1.3 1.9 1.1 3.6 0.6 0.1 1.6 0.1 0.8 0.6 0.1 0.3 0.2 3.3 11.2 0.3 2.9 3.5 0.1 3.1 1.1 0.1 0.2 0.7 3.7 0.5 0.7 2.2 0.3 0.1 0.3 18.4 0.3 0.1 0.8 0.6 0.0 0.2 0.0 0.3 0.0 0.2 0.6 1.8 0.0 0.4 0.4 1.1 404.6 0.3 1.3 0.0 0.2 631.7 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.7 1.1 0.0 0.7 0.5 36.4 0.8 0.0 0.7 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.5 0.5 0.1 1.5 4.5 0.9 0.3 0.2 0.7 0.0 0.0 0.4 0.2 0.3 0.4 0.3 0.8 64.5 0.3 4.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.5 0.0 0.0 0.8 0.0 19.3 3.7 3.6 4.0 4.8 3.5 3.6 3.6 3.5 3.6 3.3 3.5 3.7 0.3 0.0 1.5 1.0 0.4 0.3 0.4 0.1 1.8 5.1 0.2 1.1 1.5 1.5 1.3 5.5 8.4 1.3 0.1 0.6 0.0 0.0 16.1 1.0 0.7 2.1 0.0 43.5 4.1 0.0 1.4 1.1 0.0 3.2 17.8 0.1 3.6 0.0 0.2 3.3 2.8 0.0 0.0 3.1 0.7 24.8 1.8 23.0 0.0 1.0 2.9 1.3 0.0 9.5 4.6 0.1 0.0 1.9 0.1 0.3 0.0 0.0 0.0 3.0 0.0 1.8 0.7 3.4 7.4 0.5 0.0 0.7 0.6 0.1 0.3 0.3 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGA7 ENSG00000135424 "Integrin subunit alpha 7" Q13683 12 55684568-55716043 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Cell shape" "Integrin, Receptor" "Congenital muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 262.3" "Group enriched" "Detected in many" 6 "Astrocytes: 87.5;Cardiomyocytes: 124.5;Sertoli cells: 164.3;Skeletal myocytes: 65.8;Smooth muscle cells: 110.6" "Cancer enhanced" "Detected in all" "glioma: 35.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "hTERT-RPE1: 309.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008427 Uncertain Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA 1200000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "Nuclear speckles, Vesicles" "HPA008427: AB_1851823" "unprognostic (4.71e-2)" "unprognostic (1.55e-1)" "unprognostic (2.00e-3)" "unprognostic (3.02e-3)" "unprognostic (2.50e-1)" "unprognostic (2.36e-1)" "unprognostic (1.66e-2)" "unprognostic (2.20e-1)" "unprognostic (2.20e-2)" "unprognostic (3.57e-1)" "prognostic favorable (1.75e-4)" "unprognostic (2.85e-2)" "unprognostic (5.89e-2)" "unprognostic (1.79e-1)" "unprognostic (5.10e-1)" "unprognostic (2.98e-2)" "prognostic unfavorable (9.59e-5)" 133.4 8.2 18.5 18.5 21.2 1.8 69.0 15.9 30.2 28.7 16.1 97.8 17.7 45.5 12.3 23.9 56.1 30.8 157.9 34.5 17.8 11.5 10.2 15.5 6.4 21.2 21.1 19.1 5.1 6.1 12.6 1.9 20.3 33.9 8.9 2.4 14.9 37.3 262.3 16.0 27.4 95.2 16.4 10.2 35.2 8.9 23.8 3.4 26.1 154.1 3.3 46.5 25.5 21.0 0.2 4.1 7.5 12.3 66.5 13.4 0.7 5.4 8.7 11.7 11.8 8.4 6.5 2.3 7.4 3.4 0.9 1.1 5.1 0.3 10.0 0.2 3.8 0.8 2.8 3.2 0.5 0.3 2.7 19.1 0.2 64.2 0.3 309.1 0.2 2.2 0.9 1.6 37.8 5.3 0.3 3.1 20.9 1.7 0.4 0.1 28.7 0.6 0.2 0.2 0.9 2.8 0.6 0.2 48.0 4.0 0.9 13.9 0.0 1.3 12.4 0.8 8.4 3.2 2.2 0.9 57.8 8.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 18.5 21.2 15.9 30.2 34.5 17.8 21.2 21.1 20.3 16.4 23.8 21.0 11.9 0.0 0.0 87.5 0.3 1.9 0.5 0.1 0.6 2.4 1.2 3.4 124.5 2.8 0.0 1.8 4.2 0.0 0.3 0.7 0.0 0.3 0.3 1.1 1.2 9.5 7.7 0.4 17.6 0.0 0.1 5.0 0.5 1.1 0.0 6.2 0.7 1.4 0.6 0.0 9.4 1.8 0.0 1.9 2.7 0.1 6.5 2.2 3.6 9.4 0.0 3.4 0.0 6.6 3.7 0.3 0.1 6.4 0.1 0.8 2.6 0.8 0.1 0.6 164.3 65.8 110.6 4.1 2.9 0.7 2.3 0.1 0.5 0.3 0.9 0.3 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 ITGA9 "ALPHA-RLC, ITGA4L, RLC" ENSG00000144668 "Integrin subunit alpha 9" Q13797 3 37452115-37823507 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.0;Hepatic stellate cells: 54.3;Inhibitory neurons: 61.0;Leydig cells: 41.3;Microglial cells: 53.4;Oligodendrocyte precursor cells: 93.5;Peritubular cells: 74.9" "Cancer enriched" "Detected in all" 5 "thyroid cancer: 23.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 10.1;HEL: 8.1;SH-SY5Y: 11.8;SuSa: 16.9;WM-115: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030609 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 500000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Nucleoplasm, Plasma membrane, Cell Junctions" "HPA030609: AB_10600815" "unprognostic (2.35e-2)" "unprognostic (3.36e-2)" "unprognostic (5.58e-2)" "unprognostic (3.94e-2)" "unprognostic (4.48e-2)" "unprognostic (2.85e-2)" "unprognostic (3.10e-1)" "unprognostic (8.87e-3)" "unprognostic (3.23e-1)" "unprognostic (2.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.51e-1)" "unprognostic (1.78e-2)" "unprognostic (1.50e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-2)" "unprognostic (3.16e-2)" 8.8 15.5 1.9 4.5 1.8 8.5 5.9 0.0 6.2 21.8 3.6 9.6 6.3 10.6 4.0 15.5 5.4 9.4 20.1 7.8 0.7 4.0 14.8 8.9 4.1 0.9 1.3 5.0 1.8 2.6 1.7 9.8 0.4 12.5 6.8 0.7 4.2 10.8 2.8 3.0 9.1 15.8 0.7 22.6 7.5 6.9 5.0 1.8 20.7 9.8 2.4 6.5 4.5 1.2 0.2 0.0 4.3 0.3 0.0 0.2 0.1 0.1 0.0 0.0 0.0 10.1 0.0 3.2 1.4 0.0 0.1 0.2 3.8 0.0 0.0 0.1 0.6 8.1 0.1 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.4 0.3 0.0 0.2 0.5 11.8 0.1 0.5 0.7 16.9 0.0 3.1 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.1 0.2 6.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.8 0.0 6.2 7.8 0.7 0.9 1.3 0.4 0.7 5.0 1.2 20.8 0.0 14.7 16.0 0.1 2.5 1.1 0.1 1.2 1.2 1.1 2.9 12.9 2.8 3.1 1.8 0.0 0.2 0.0 0.0 0.0 0.1 1.5 1.4 4.9 21.6 0.0 3.0 82.0 0.0 0.5 7.5 0.0 0.9 6.3 36.2 54.3 1.3 2.8 0.0 61.0 0.1 0.0 31.9 2.2 4.2 41.3 5.7 3.6 53.4 0.1 0.6 0.0 93.5 6.2 0.0 0.0 74.9 0.4 0.2 0.0 0.1 0.0 0.0 0.0 3.2 3.3 0.6 0.9 0.0 1.7 0.3 1.8 25.9 0.4 0.3 ITGB1 "CD29, FNRB, GPIIA, MDF2, MSK12" ENSG00000150093 "Integrin subunit beta 1" P05556 10 32887273-33005792 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 1206.9;Pancreatic endocrine cells: 1393.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-RPE1: 2711.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003434, HPA059297, HPA069003" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Focal adhesion sites" NA NA 270000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Focal adhesion sites" "Endoplasmic reticulum" "CAB003434: AB_303570, HPA059297: AB_2732634, HPA069003: AB_2732125" "unprognostic (3.07e-2)" "prognostic unfavorable (5.01e-4)" "unprognostic (8.67e-2)" "unprognostic (4.36e-1)" "unprognostic (1.20e-2)" "unprognostic (3.87e-2)" "unprognostic (1.60e-2)" "prognostic unfavorable (3.36e-6)" "unprognostic (3.22e-1)" "unprognostic (2.36e-3)" "unprognostic (3.68e-3)" "unprognostic (2.42e-1)" "unprognostic (1.02e-3)" "unprognostic (1.25e-2)" "unprognostic (2.23e-1)" "unprognostic (2.48e-1)" "unprognostic (3.08e-2)" 491.9 179.3 61.5 241.5 78.2 81.5 216.2 75.0 90.9 259.2 68.3 265.3 147.4 330.4 171.7 168.6 172.0 347.4 390.3 60.2 74.3 180.4 287.1 233.6 118.0 88.4 80.6 157.1 135.3 145.4 59.8 459.5 88.9 248.1 223.6 27.7 130.7 427.7 157.9 92.2 150.8 710.0 76.6 204.7 160.1 91.2 86.4 77.5 161.5 194.5 106.2 357.4 119.1 88.9 638.0 907.0 495.4 559.6 1183.4 1019.5 398.1 2063.9 1239.6 999.0 903.9 215.9 1478.2 164.5 354.1 1830.9 638.0 438.9 149.1 1204.1 1122.0 163.1 112.7 195.8 416.3 253.6 826.4 48.3 195.5 1027.7 658.2 1040.8 426.0 2711.1 1263.6 81.0 136.6 76.5 1700.8 109.0 80.1 46.7 107.4 200.6 428.2 52.0 357.0 30.9 1454.8 186.2 108.0 271.4 649.9 114.6 498.2 813.7 153.9 175.0 1362.6 1280.0 712.2 904.2 719.7 64.7 14.8 91.2 956.6 198.2 518.5 7.5 35.1 16.1 83.4 69.8 22.8 109.6 191.8 138.7 33.9 40.3 24.9 68.4 9.0 90.3 108.2 11.4 266.8 117.2 61.5 78.2 75.0 90.9 60.2 74.3 88.4 80.6 88.9 76.6 86.4 88.9 631.5 342.9 143.8 26.4 118.0 546.7 435.5 531.6 208.3 32.8 147.1 307.5 210.8 241.6 268.1 226.2 31.3 210.3 217.8 179.8 13.7 1206.9 6.6 194.6 437.9 421.1 193.3 153.0 37.2 411.3 515.2 374.7 95.8 406.5 88.7 561.8 375.9 268.1 179.8 38.7 52.4 97.4 213.6 170.1 206.7 18.3 254.5 217.8 343.3 67.5 119.4 72.0 111.2 42.7 66.8 1393.7 128.5 601.8 181.2 412.5 75.6 68.7 171.5 45.5 637.7 236.3 724.0 10.1 76.0 84.4 170.5 219.7 211.3 225.6 127.0 296.1 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 459.9;hTERT-RPE1: 508.7;WM-115: 477.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001820, CAB022050" Approved Approved "Plasma membrane,Mitochondria" NA NA 64000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: AB_1079142" "unprognostic (2.63e-1)" "unprognostic (1.04e-1)" "unprognostic (3.57e-1)" "unprognostic (4.44e-2)" "unprognostic (1.37e-2)" "unprognostic (6.07e-2)" "unprognostic (3.49e-3)" "unprognostic (3.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.16e-1)" "unprognostic (2.16e-3)" "unprognostic (2.49e-3)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (4.38e-3)" 102.7 32.5 24.4 26.0 33.4 3.3 71.3 32.6 20.3 84.7 71.0 48.1 33.1 75.9 16.4 54.9 33.2 71.7 68.8 24.6 28.7 48.6 51.4 53.9 6.0 38.2 32.9 28.0 23.1 21.8 20.5 82.3 35.4 37.3 24.9 14.3 49.6 46.9 30.0 88.9 32.5 60.1 32.3 41.0 29.7 13.5 32.5 12.2 34.3 33.7 9.9 40.3 70.0 35.8 189.1 459.9 32.4 82.7 296.6 84.2 166.3 197.5 120.0 35.9 57.6 92.6 240.3 0.8 93.5 336.3 177.0 148.0 29.5 102.7 31.2 2.0 20.1 66.3 69.5 98.0 51.0 0.4 116.8 51.2 23.2 91.1 46.9 508.7 121.2 0.2 60.7 98.1 122.7 190.0 0.8 1.1 145.8 105.1 50.4 0.4 52.2 71.8 98.8 41.2 0.9 67.5 146.6 214.5 165.7 56.4 121.9 4.2 318.2 134.9 200.7 118.5 103.7 16.6 18.4 1.3 141.3 0.8 477.0 0.3 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.0 2.5 24.4 33.4 32.6 20.3 24.6 28.7 38.2 32.9 35.4 32.3 32.5 35.8 50.4 6.4 6.7 55.5 1.0 17.2 23.1 18.8 6.2 8.1 20.6 27.2 28.9 42.9 10.0 29.5 4.2 68.5 0.6 34.9 11.7 38.3 10.7 22.0 21.4 27.5 3.5 2.7 0.9 18.8 7.4 52.1 11.2 13.4 0.0 135.9 31.1 39.1 72.3 35.3 18.1 12.9 2.0 36.8 17.5 4.1 20.2 28.5 10.6 60.9 0.4 50.2 0.0 16.6 12.5 70.4 27.0 16.6 0.6 24.9 21.0 10.7 6.2 14.9 39.5 31.3 52.1 2.6 7.0 15.6 22.3 55.1 1.7 1.0 16.3 14.8 ITGB6 ENSG00000115221 "Integrin subunit beta 6" P18564 2 160099667-160200313 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Amelogenesis imperfecta, Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 68.3;skeletal muscle: 80.0;tongue: 64.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 153.8;Alveolar cells type 2: 202.5;Basal prostatic cells: 153.5;Basal respiratory cells: 125.9;Pancreatic endocrine cells: 195.2;Spermatocytes: 286.0;Urothelial cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "CAPAN-2: 139.2;RPTEC TERT1: 269.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA023626, CAB073536" Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Cell Junctions" Centrosome "CAB073536: , HPA023626: AB_2671267" "unprognostic (1.27e-1)" "unprognostic (1.57e-2)" "unprognostic (6.90e-2)" "unprognostic (8.22e-3)" "unprognostic (3.61e-3)" "unprognostic (1.50e-2)" "unprognostic (1.72e-3)" "unprognostic (2.04e-2)" "unprognostic (1.72e-1)" "unprognostic (7.06e-2)" "prognostic unfavorable (5.03e-6)" "unprognostic (1.04e-1)" "unprognostic (2.73e-1)" "unprognostic (4.97e-2)" "unprognostic (1.23e-1)" "unprognostic (2.16e-1)" "unprognostic (1.00e-1)" 0.1 0.0 0.0 1.9 0.0 0.0 20.2 0.0 0.0 2.7 0.0 8.0 8.4 5.4 1.7 14.2 3.4 14.8 0.6 0.0 0.0 68.3 0.1 45.3 0.0 0.0 0.0 0.0 3.3 32.2 1.8 5.5 0.0 5.1 7.4 0.0 3.9 8.9 80.0 2.6 6.3 0.3 0.0 0.0 18.7 0.1 0.0 0.0 4.7 64.5 3.0 44.9 6.5 0.0 14.5 0.2 0.0 0.1 0.0 0.0 14.9 0.0 0.0 0.0 0.0 0.1 139.2 0.1 0.8 0.1 0.0 28.7 0.0 45.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.5 31.4 0.0 0.1 0.4 0.1 0.0 0.0 0.0 3.8 4.3 0.0 0.0 0.0 9.0 0.0 0.0 10.9 0.0 269.9 45.7 0.0 0.1 0.1 43.7 0.0 1.6 0.5 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 153.8 202.5 0.0 0.0 10.5 153.5 125.9 46.1 0.0 35.5 31.0 38.7 10.0 60.4 71.7 0.0 13.6 0.5 30.3 0.0 57.5 89.4 9.6 0.7 2.6 0.0 0.0 0.3 105.4 7.0 2.6 37.8 24.4 3.8 0.0 1.1 1.0 2.2 0.0 0.2 11.6 24.4 0.3 0.4 48.3 2.8 2.2 1.8 0.0 2.0 1.7 0.0 0.5 0.1 195.2 25.6 1.2 0.0 57.3 10.0 1.9 17.7 0.1 0.0 5.7 3.8 286.0 3.0 42.2 8.5 4.7 2.1 0.0 12.4 129.3 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9;choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 376.2;Glandular and luminal cells: 551.9;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 133 "basophil: 16.5" "Lineage enriched" "Detected in single" 133 "granulocytes: 16.5" "Cell line enhanced" "Detected in many" "AF22: 44.3;EFO-21: 54.6;RPTEC TERT1: 88.1;WM-115: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" 3.8 2.6 25.7 4.2 41.8 0.3 9.6 53.9 19.2 15.4 39.4 3.7 3.2 7.7 14.0 6.4 7.5 8.7 2.9 19.5 37.5 21.6 0.8 2.4 0.5 38.9 48.4 4.7 13.3 5.1 5.4 5.2 42.7 6.7 2.8 4.6 13.6 9.0 0.2 6.3 4.2 3.0 39.7 0.0 4.2 6.5 35.6 0.8 2.1 0.9 6.9 7.2 9.0 48.6 28.2 1.1 44.3 5.6 3.7 15.2 0.0 0.1 0.5 0.2 1.5 0.3 6.9 0.0 54.6 2.0 1.7 30.1 1.9 4.5 0.5 0.0 0.7 0.0 23.1 0.0 1.8 0.0 0.1 1.8 12.6 0.5 2.4 27.1 2.4 0.0 0.0 8.3 0.8 0.1 0.0 0.0 3.3 0.4 4.8 0.0 3.7 0.0 88.1 2.5 0.7 1.9 8.6 0.2 23.5 0.8 0.7 0.1 3.0 11.2 7.1 3.2 5.8 10.2 0.1 0.0 2.7 0.0 127.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 25.7 41.8 53.9 19.2 19.5 37.5 38.9 48.4 42.7 39.7 35.6 48.6 0.7 12.8 4.8 106.4 2.5 33.1 117.2 39.4 34.7 13.3 26.3 18.7 3.0 38.6 57.9 38.6 0.0 20.0 0.4 5.0 7.9 26.3 3.0 376.2 150.6 5.2 34.0 0.0 28.1 17.4 1.2 15.5 7.7 551.9 1.3 0.9 1.4 0.2 3.3 1.7 8.2 7.4 34.6 1.0 4.7 6.5 44.1 9.8 3.6 4.7 31.6 24.3 0.0 192.0 119.2 35.8 6.1 44.8 2.0 149.7 14.5 76.7 100.1 1.4 0.0 4.8 7.0 1.4 1.1 34.6 12.4 4.9 5.5 1.9 9.6 150.7 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITM2A "BRICD2A, E25A" ENSG00000078596 "Integral membrane protein 2A" O43736 X 79360384-79367667 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 322.9" "Cell type enhanced" "Detected in many" "Adipocytes: 390.0;Endothelial cells: 368.4;Fibroblasts: 302.1;granulocytes: 194.6;Leydig cells: 335.5;Muller glia cells: 188.9;T-cells: 239.2" "Cancer enhanced" "Detected in all" "glioma: 51.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "basophil: 172.6;eosinophil: 88.5;gdT-cell: 107.1;MAIT T-cell: 79.3;memory CD4 T-cell: 204.7;memory CD8 T-cell: 170.5;naive CD4 T-cell: 216.7;naive CD8 T-cell: 101.6;NK-cell: 130.3;T-reg: 168.1" "Group enriched" "Detected in all" 7 "granulocytes: 172.6;NK-cells: 130.3;T-cells: 216.7" "Cell line enriched" "Detected in some" 5 "MOLT-4: 1749.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000296 Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Golgi apparatus, Plasma membrane" "HPA000296: " "unprognostic (1.05e-2)" "unprognostic (5.22e-3)" "unprognostic (2.77e-3)" "unprognostic (5.65e-2)" "unprognostic (1.73e-2)" "unprognostic (1.06e-3)" "prognostic favorable (3.66e-6)" "unprognostic (1.57e-1)" "unprognostic (4.94e-2)" "unprognostic (9.85e-2)" "unprognostic (1.33e-2)" "unprognostic (2.57e-1)" "unprognostic (1.04e-2)" "unprognostic (1.56e-1)" "unprognostic (3.31e-1)" "unprognostic (2.18e-1)" "unprognostic (4.30e-1)" 80.2 10.8 103.4 26.8 95.2 45.8 74.5 99.4 172.0 55.3 75.5 30.5 15.1 44.4 18.8 40.1 42.8 28.8 115.3 92.1 105.4 20.6 6.3 52.2 87.2 101.5 102.2 181.4 10.0 14.9 21.0 29.7 102.0 22.8 32.2 11.9 74.9 22.4 41.2 25.0 22.1 56.6 95.2 24.5 24.2 15.9 109.8 322.9 83.1 75.2 46.9 42.3 26.0 95.8 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 216.6 2.5 0.0 4.4 0.0 69.9 0.0 0.0 0.0 113.1 124.2 19.5 0.0 0.0 0.0 0.1 0.0 333.3 80.2 0.0 0.0 0.0 1749.0 77.6 25.0 0.0 0.0 0.7 0.1 0.3 64.6 0.0 0.2 19.0 0.0 0.9 0.0 17.6 2.2 2.5 3.0 0.0 1.8 0.4 1.1 208.1 0.0 0.0 0.2 0.0 8.7 172.6 0.8 88.5 107.1 1.3 79.3 23.4 204.7 170.5 0.8 23.5 216.7 101.6 3.9 130.3 1.1 6.1 168.1 115.3 103.4 95.2 99.4 172.0 92.1 105.4 101.5 102.2 102.0 95.2 109.8 95.8 390.0 3.2 14.8 1.0 28.0 67.4 13.2 2.1 50.1 3.1 21.1 81.9 29.3 2.8 4.4 1.8 0.0 0.4 64.8 2.1 5.9 0.4 3.1 0.4 2.6 368.4 2.4 42.7 3.5 50.9 0.2 302.1 29.6 0.6 194.6 1.4 135.0 1.0 1.3 1.7 2.3 85.6 0.0 9.5 39.5 7.1 335.5 8.6 62.2 114.3 3.2 188.9 65.9 18.1 60.2 1.0 1.4 117.8 81.8 12.3 0.2 1.4 0.7 12.1 0.0 31.8 22.5 0.5 2.6 24.3 47.0 0.3 239.2 2.0 2.9 2.5 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;intestine: 18.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 51.4;Early spermatids: 45.4;Gastric mucus-secreting cells: 34.1;Late spermatids: 166.4;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "Hep G2: 33.6;OE19: 18.2" "Low region specificity" "Detected in all" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.2 7.3 21.4 0.7 26.7 0.4 0.2 13.8 36.5 1.3 10.9 10.7 17.6 0.3 0.1 0.3 0.5 0.2 2.6 28.7 12.4 0.2 1.7 0.5 0.1 10.9 12.0 0.3 1.9 2.0 0.4 0.3 11.6 0.8 2.7 0.3 1.4 0.3 4.4 0.4 18.1 0.3 11.3 0.2 10.9 10.4 12.1 0.0 0.2 0.0 0.0 0.6 0.9 20.4 7.1 1.9 0.3 7.9 0.0 2.5 14.3 4.3 3.4 2.8 2.9 16.3 0.3 0.0 3.5 0.4 6.3 0.8 3.4 0.3 0.2 6.6 4.3 9.9 4.7 33.6 12.6 3.4 0.5 0.2 0.2 2.7 0.8 1.6 0.2 1.3 12.9 1.9 1.0 4.7 0.3 6.5 0.9 18.2 5.6 1.7 1.4 0.6 0.3 0.4 0.7 1.5 3.2 0.0 0.3 0.0 0.9 5.0 0.3 6.9 7.1 7.7 11.8 1.0 10.8 0.0 12.6 13.2 2.3 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 21.4 26.7 13.8 36.5 28.7 12.4 10.9 12.0 11.6 11.3 12.1 20.4 0.1 0.0 0.0 3.3 0.5 0.1 0.3 0.1 0.0 0.0 0.3 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.1 51.4 0.0 0.1 45.4 0.3 2.4 0.5 0.0 0.8 23.7 0.7 0.5 0.3 34.1 0.3 0.0 1.0 0.4 0.3 0.2 0.0 0.8 12.0 0.0 0.0 0.0 166.4 2.5 0.4 0.0 1.9 0.0 7.9 0.0 1.5 2.9 0.8 16.1 1.5 0.1 0.1 35.8 0.1 0.1 0.2 6.6 0.3 0.5 14.4 4.9 0.0 0.0 0.1 0.4 0.1 18.7 0.2 ITPRID2 "CS-1, KIAA1927, KRAP, SPAG13, SSFA2" ENSG00000138434 "ITPR interacting domain containing 2" P28290 2 181891730-181930738 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pancreas: 175.8" "Cell type enhanced" "Detected in some" "Adipocytes: 30.7;Cardiomyocytes: 30.0;Cytotrophoblasts: 25.7;Extravillous trophoblasts: 26.8;Hofbauer cells: 20.4;Syncytiotrophoblasts: 33.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 5 "dendritic cells: 2.7;granulocytes: 6.1;monocytes: 5.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034665, HPA039989" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" Nucleoplasm "HPA034665: AB_2674271, HPA039989: AB_2676788" "unprognostic (1.68e-1)" "unprognostic (3.27e-2)" "unprognostic (2.17e-2)" "unprognostic (4.70e-2)" "unprognostic (8.77e-2)" "unprognostic (8.87e-2)" "unprognostic (2.13e-1)" "unprognostic (4.74e-2)" "unprognostic (5.63e-2)" "unprognostic (1.23e-2)" "prognostic unfavorable (8.19e-4)" "unprognostic (6.95e-2)" "prognostic favorable (2.91e-5)" "unprognostic (3.39e-1)" "unprognostic (5.54e-2)" "unprognostic (4.95e-2)" "prognostic unfavorable (5.79e-5)" 30.8 20.7 55.0 20.6 62.9 42.4 32.1 57.2 66.2 30.9 50.3 50.4 36.4 25.8 18.4 22.8 20.3 37.7 24.4 45.5 61.5 48.4 79.3 44.9 17.6 65.2 60.5 13.6 175.8 20.9 18.3 34.7 63.3 34.0 44.2 16.9 69.9 17.1 31.9 112.9 34.0 25.6 57.3 32.4 56.1 37.4 62.6 24.1 36.5 23.4 16.0 31.3 29.5 61.1 56.0 25.8 71.6 12.6 53.8 41.3 21.7 94.6 82.6 29.1 37.0 25.9 56.0 1.2 30.7 59.7 31.5 46.2 14.5 41.6 56.6 25.2 20.3 52.5 106.6 23.5 45.7 28.5 48.9 30.0 64.4 51.3 57.7 66.7 145.8 22.3 25.0 29.5 82.9 28.7 25.4 41.0 5.0 47.0 62.5 18.7 29.3 19.2 87.0 16.3 13.7 12.1 55.7 19.7 91.0 27.6 14.2 61.6 68.1 73.1 37.0 27.5 50.3 20.9 9.4 21.9 34.0 17.1 57.2 6.1 2.8 4.2 0.9 2.7 0.6 0.4 0.6 0.6 2.7 0.9 0.8 0.7 4.7 0.8 5.1 2.1 0.4 1.3 55.0 62.9 57.2 66.2 45.5 61.5 65.2 60.5 63.3 57.3 62.6 61.1 30.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 25.7 5.8 0.0 0.0 0.0 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 26.8 7.7 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 0.0 0.0 0.0 0.0 33.4 1.1 0.0 0.0 0.0 ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Inhibitory neurons: 151.9;Rod photoreceptor cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" 55.5 15.5 18.0 9.9 18.4 6.8 27.9 16.4 26.2 19.8 22.8 14.7 8.9 20.3 12.0 11.4 16.7 19.8 20.9 18.3 14.0 10.9 26.4 11.5 6.8 14.5 13.6 19.6 5.0 7.0 6.7 24.4 14.9 14.5 11.0 28.5 7.9 22.3 22.0 11.9 9.7 18.4 8.8 15.4 11.1 12.3 17.0 5.0 10.3 22.0 3.9 15.4 13.4 14.1 36.3 14.9 70.4 23.4 32.3 30.8 115.3 35.8 34.4 20.6 19.8 56.7 27.0 8.5 28.3 43.1 42.7 13.7 42.2 24.9 22.0 3.5 18.6 10.3 30.9 26.7 24.4 7.4 9.9 30.5 22.0 38.6 21.2 23.5 55.3 9.8 13.7 5.8 33.4 8.2 10.3 9.8 104.5 12.6 11.3 13.2 33.7 17.6 30.9 14.7 13.2 14.4 51.4 10.6 12.6 44.6 13.0 7.2 50.2 22.9 30.9 18.1 12.5 7.0 20.8 7.9 20.8 22.9 26.0 0.0 4.2 5.5 0.3 3.2 0.3 0.0 0.5 0.1 1.3 0.0 0.2 0.1 0.2 0.1 5.1 0.3 0.0 0.8 18.0 18.4 16.4 26.2 18.3 14.0 14.5 13.6 14.9 8.8 17.0 14.1 19.8 25.6 18.6 217.4 1.8 18.1 22.6 10.8 36.5 73.1 12.2 8.1 81.8 18.6 14.5 11.0 91.8 20.8 1.1 22.4 0.0 19.9 10.2 13.3 67.7 21.3 9.1 47.4 110.9 12.5 28.0 31.9 19.4 21.0 2.5 30.7 28.2 54.2 55.6 65.6 151.9 7.2 20.3 30.0 10.9 8.6 24.8 27.3 10.6 74.0 10.8 46.9 0.0 80.4 46.4 37.1 10.3 71.5 3.1 18.3 16.8 16.6 18.8 146.2 13.1 20.1 39.7 32.4 47.7 8.9 11.8 15.6 2.7 21.4 10.5 27.2 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 211.1;Endometrial ciliated cells: 197.4;Smooth muscle cells: 190.1;Squamous epithelial cells: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 219.2;hTERT-HME1: 131.1;U-251 MG: 187.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" 44.2 10.1 10.3 13.0 9.5 21.8 30.3 8.4 12.0 44.0 8.9 23.7 13.8 27.3 19.5 52.4 27.0 21.6 20.7 12.8 9.8 21.7 6.2 23.9 8.4 12.4 14.2 20.3 22.0 20.9 8.2 67.9 10.0 25.9 23.0 22.1 15.8 26.7 9.8 57.2 13.6 23.6 9.7 23.3 25.1 4.5 12.1 9.3 19.9 22.8 15.6 28.5 50.0 8.5 4.1 20.6 63.1 78.1 11.8 11.3 2.3 2.4 11.9 3.3 1.8 18.5 11.2 0.7 59.0 2.4 17.7 85.8 9.4 219.2 2.7 0.2 4.5 7.0 2.2 87.9 5.8 28.4 0.5 4.6 63.7 10.6 131.1 12.5 21.1 0.3 0.1 8.8 6.0 0.2 0.0 20.2 18.2 68.7 20.3 5.3 3.9 13.1 29.9 25.6 2.8 2.1 6.3 4.4 26.2 49.8 0.3 3.3 80.5 14.2 9.9 11.8 187.9 3.6 0.6 0.9 9.1 10.3 11.3 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 10.3 9.5 8.4 12.0 12.8 9.8 12.4 14.2 10.0 9.7 12.1 8.5 73.0 41.7 15.4 5.9 1.1 104.6 54.9 76.3 211.1 9.7 13.2 29.1 20.6 30.0 34.4 16.5 43.8 16.9 6.8 64.3 1.9 31.6 5.0 197.4 22.2 102.5 5.3 0.0 6.9 30.4 1.0 41.9 76.0 96.4 7.0 2.7 60.0 1.8 4.2 21.9 9.2 12.8 20.3 5.9 33.9 9.6 21.5 9.1 14.2 22.5 2.8 11.9 2.1 24.6 1.3 97.3 18.3 33.8 4.3 24.5 7.8 2.3 30.2 69.1 85.5 46.7 190.1 0.9 3.2 343.9 106.8 2.2 4.3 107.2 39.1 33.7 JAK2 JTK10 ENSG00000096968 "Janus kinase 2" O60674 9 4984390-5129948 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Chromatin regulator, Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 93.4;Inhibitory neurons: 122.3;Microglial cells: 106.8;Oligodendrocyte precursor cells: 69.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 132.5" "Lineage enriched" "Detected in all" 5 "granulocytes: 132.5" "Group enriched" "Detected in many" 5 "ASC diff: 42.2;HDLM-2: 75.0;HEL: 154.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013089, HPA040820, HPA043870" Approved Supported "Nucleoplasm,Plasma membrane,Focal adhesion sites" No No "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Focal adhesion sites" "CAB013089: AB_2533647, HPA040820: AB_2677151, HPA043870: AB_2678708" "unprognostic (2.24e-3)" "unprognostic (2.76e-2)" "unprognostic (1.50e-2)" "unprognostic (7.67e-2)" "unprognostic (5.50e-2)" "unprognostic (3.09e-2)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (1.09e-1)" "unprognostic (5.49e-3)" "unprognostic (1.58e-1)" "unprognostic (1.72e-2)" "unprognostic (3.85e-1)" "unprognostic (4.53e-2)" "unprognostic (3.43e-2)" "unprognostic (1.96e-1)" "unprognostic (7.37e-3)" 15.6 7.6 3.2 19.2 3.7 21.7 8.9 6.3 9.1 8.5 1.1 6.7 6.5 11.3 8.6 8.8 8.0 10.5 24.5 2.7 3.1 6.8 4.5 10.9 18.2 3.3 1.8 11.5 3.8 6.5 2.9 11.0 2.0 6.8 6.5 12.8 4.0 6.2 9.8 11.2 7.7 9.5 3.5 17.6 13.4 9.8 1.7 7.5 4.8 8.9 12.7 11.7 9.1 3.9 6.8 3.7 3.7 6.3 42.2 12.4 1.1 9.1 8.6 7.2 4.6 1.2 2.0 0.3 2.1 5.4 5.4 2.3 4.4 5.1 4.9 75.0 1.4 154.7 7.6 1.7 10.0 10.5 7.1 9.5 2.1 2.8 4.5 7.6 6.6 5.1 10.9 17.4 11.6 2.2 2.9 12.8 3.3 3.3 4.3 5.1 8.2 2.2 4.7 3.5 4.2 2.4 2.6 3.5 2.8 3.6 2.0 15.4 13.1 10.2 3.6 10.7 6.4 3.1 6.4 1.5 13.6 4.7 5.3 132.5 20.5 38.2 5.6 20.1 4.5 5.6 4.1 3.1 26.5 4.9 2.2 2.8 19.2 9.6 16.4 9.7 4.5 7.7 3.2 3.7 6.3 9.1 2.7 3.1 3.3 1.8 2.0 3.5 1.7 3.9 14.3 16.0 7.9 31.6 12.9 9.7 3.3 4.9 10.8 8.0 5.2 3.4 30.0 0.0 6.7 7.3 8.4 1.9 13.9 11.7 1.9 3.3 8.6 5.1 11.2 9.4 3.0 19.8 93.4 3.9 0.9 8.9 38.7 5.6 14.0 11.4 4.6 1.9 14.2 8.4 122.3 4.5 0.0 33.6 28.8 7.1 23.6 38.9 5.4 106.8 49.5 12.6 8.2 69.9 42.3 7.0 20.9 33.4 10.7 3.0 3.9 3.3 7.1 11.2 0.0 9.7 12.5 15.0 5.5 11.6 8.4 3.4 10.4 5.1 4.1 4.5 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JCAD KIAA1462 ENSG00000165757 "Junctional cadherin 5 associated" Q9P266 10 30012803-30115494 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 4 "Adipocytes: 106.8;Endothelial cells: 30.3;Granulosa cells: 72.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 29.3;HUVEC TERT2: 29.9;LHCN-M2: 24.9;TIME: 67.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017956 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Cell Junctions" "HPA017956: AB_1852408" "unprognostic (1.78e-1)" "unprognostic (8.33e-2)" "unprognostic (5.37e-2)" "unprognostic (8.07e-2)" "unprognostic (6.32e-2)" "unprognostic (7.09e-2)" "unprognostic (9.36e-2)" "unprognostic (1.28e-1)" "unprognostic (1.16e-1)" "unprognostic (4.93e-2)" "unprognostic (1.33e-1)" "unprognostic (3.08e-2)" "prognostic unfavorable (2.54e-4)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.41e-1)" "unprognostic (1.13e-2)" "unprognostic (1.34e-2)" 31.2 7.5 13.5 5.2 21.2 0.1 13.0 5.1 13.0 6.5 3.1 36.0 1.4 17.3 7.5 5.9 12.5 10.4 18.3 10.8 7.2 6.7 1.8 24.2 3.5 12.5 8.4 10.9 16.9 4.9 4.5 33.6 10.1 7.8 3.9 13.1 2.4 9.5 9.9 3.7 3.7 17.3 7.3 0.9 4.5 14.0 13.3 6.1 13.6 14.8 1.8 18.3 4.4 8.1 15.3 6.7 5.9 0.0 3.7 0.9 8.6 8.1 8.5 1.2 2.0 2.6 0.1 0.0 0.6 29.3 1.7 0.3 1.6 0.5 3.3 1.7 3.6 0.0 0.0 0.1 16.0 0.0 1.0 9.1 0.2 19.9 1.5 0.5 29.9 0.4 0.0 0.0 24.9 0.5 0.0 0.7 1.2 0.9 10.2 0.0 3.3 0.0 1.2 0.3 0.8 0.1 0.3 0.1 0.0 8.4 0.0 1.4 67.8 14.9 3.6 4.7 0.7 6.2 0.8 0.0 3.5 10.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 21.2 5.1 13.0 10.8 7.2 12.5 8.4 10.1 7.3 13.3 8.1 106.8 0.0 3.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 2.7 0.4 0.0 0.0 16.4 0.0 1.3 8.5 30.3 0.0 0.0 0.0 0.4 0.9 2.2 0.0 0.8 1.3 72.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.3 2.9 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.4 0.2 7.1 0.0 0.0 JMJD4 FLJ12517 ENSG00000081692 "Jumonji domain containing 4" Q9H9V9 1 227730425-227735411 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 74.0;Late spermatids: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027260, HPA052861" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Vesicles "HPA027260: AB_10602608, HPA052861: AB_2681975" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (4.86e-2)" "unprognostic (2.29e-1)" "unprognostic (1.43e-1)" "unprognostic (2.86e-1)" "unprognostic (1.23e-1)" "unprognostic (6.19e-2)" "unprognostic (1.74e-2)" "unprognostic (4.31e-2)" "unprognostic (8.69e-3)" "unprognostic (8.68e-3)" "prognostic unfavorable (3.16e-4)" "unprognostic (4.45e-2)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (4.68e-1)" 6.8 12.8 8.5 4.8 7.9 3.6 7.1 7.7 9.4 6.2 8.1 6.2 4.3 8.1 4.8 6.8 7.0 4.1 7.4 8.6 8.4 7.4 11.9 5.2 6.9 9.0 9.2 7.9 9.6 5.8 10.0 4.0 9.3 9.7 2.4 1.6 8.7 5.6 10.2 6.0 6.2 4.2 8.3 9.0 5.9 14.8 8.6 6.5 6.4 4.7 4.4 6.8 4.6 8.9 18.4 26.4 8.4 9.3 9.0 5.1 31.0 11.3 11.6 17.0 10.4 22.6 15.2 24.3 16.8 10.7 9.1 18.1 5.8 17.9 2.0 13.2 29.4 14.9 13.3 17.8 15.8 15.7 7.1 9.0 11.1 16.2 11.8 6.7 8.8 17.5 19.7 7.8 8.3 15.4 19.5 8.3 14.6 13.9 42.2 17.8 10.3 21.9 10.1 16.7 16.4 11.1 10.8 37.4 14.5 4.3 30.2 16.9 7.7 8.6 8.8 10.6 21.0 14.5 5.0 9.3 8.6 7.6 24.1 3.2 7.2 2.8 11.1 7.4 12.2 8.7 8.4 7.7 6.6 8.6 13.1 11.4 0.7 14.3 4.1 13.2 10.2 8.0 8.5 7.9 7.7 9.4 8.6 8.4 9.0 9.2 9.3 8.3 8.6 8.9 7.0 6.4 7.2 4.6 7.9 4.1 8.0 8.6 1.8 14.0 16.6 13.2 3.7 4.3 7.4 7.3 0.0 13.1 7.2 8.8 5.9 21.7 74.0 5.2 11.0 6.9 9.0 13.9 4.4 28.9 14.0 9.7 10.7 4.9 7.0 12.7 6.8 14.5 16.9 11.8 3.3 6.9 2.0 7.6 2.1 204.9 11.5 6.1 12.4 2.8 11.0 12.2 13.4 3.0 2.1 23.7 5.6 4.1 14.7 11.0 12.9 12.5 7.7 14.7 6.6 6.7 8.2 36.1 7.5 7.4 4.7 9.6 7.3 13.3 7.3 7.5 JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.3;Ductal cells: 90.1;Endometrial ciliated cells: 107.3;Extravillous trophoblasts: 205.9;Glandular and luminal cells: 77.5;Pancreatic endocrine cells: 78.9;Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Approved Approved "Plasma membrane,Cytosol" NA NA 76000 "Cluster 22: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041888: AB_10793937, HPA041908: AB_10794160" "unprognostic (1.49e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-3)" "prognostic favorable (7.85e-4)" "unprognostic (3.60e-1)" "unprognostic (2.37e-2)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.22e-3)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (2.78e-2)" 21.2 17.0 12.7 18.6 21.1 11.3 36.4 33.2 19.8 39.5 14.1 32.7 21.9 21.1 17.9 47.7 63.4 13.6 20.3 12.0 16.3 48.8 41.1 20.0 19.9 58.0 27.8 19.8 29.6 20.9 15.1 48.1 46.9 47.9 30.5 4.6 26.6 18.2 17.5 31.3 24.2 19.5 28.4 12.8 28.2 18.1 25.6 35.5 27.7 14.0 31.3 31.2 25.9 51.7 148.1 147.5 168.4 93.9 23.9 39.3 151.9 143.6 44.8 117.7 99.8 194.5 188.3 94.6 107.8 71.1 116.4 141.9 223.5 194.2 135.7 77.2 135.2 78.4 80.2 111.4 36.7 93.5 44.8 28.1 121.6 116.4 149.6 64.9 75.7 85.4 187.5 37.0 68.6 169.5 117.1 46.6 185.3 164.4 112.0 212.7 159.3 136.2 186.2 82.5 156.1 85.6 214.9 205.3 66.5 161.1 250.3 59.6 87.9 113.9 201.1 54.8 141.1 31.5 136.3 198.8 35.8 71.5 170.5 2.1 3.7 4.1 5.2 3.3 7.2 4.8 5.8 4.2 2.8 7.6 6.3 5.4 0.3 6.8 1.7 6.6 5.8 4.4 12.7 21.1 33.2 19.8 12.0 16.3 58.0 27.8 46.9 28.4 25.6 51.7 11.9 25.6 10.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 33.3 23.4 0.0 0.0 12.4 9.2 0.0 99.3 4.5 0.0 43.0 90.1 0.0 107.3 19.2 8.5 0.0 0.0 0.0 25.6 205.9 7.4 0.0 77.5 2.5 23.4 0.0 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 28.4 0.0 0.0 0.0 0.0 78.9 0.0 0.0 1.2 0.0 0.0 26.0 27.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 168.7 3.6 18.9 0.0 0.0 JUP "CTNNG, DP3, DPIII, PDGB, PKGB" ENSG00000173801 "Junction plakoglobin" P14923 17 41754604-41786931 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes, Cardiomyopathy, Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 952.2;skin 1: 932.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 315.9;Pancreatic endocrine cells: 356.2;Squamous epithelial cells: 318.3;Suprabasal keratinocytes: 383.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 13.1;eosinophil: 28.7;intermediate monocyte: 22.6;memory B-cell: 13.5;myeloid DC: 14.5;naive B-cell: 11.7;non-classical monocyte: 43.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 1090.1;OE19: 3919.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002139, HPA032047" Supported Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 64000000 "Cluster 14: Monocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Vesicles "CAB002139: AB_563468, HPA032047: AB_2674124" "unprognostic (3.96e-3)" "unprognostic (3.40e-1)" "unprognostic (2.32e-1)" "unprognostic (4.71e-3)" "unprognostic (2.49e-2)" "unprognostic (1.12e-1)" "unprognostic (2.02e-1)" "unprognostic (8.11e-3)" "unprognostic (1.41e-2)" "unprognostic (9.85e-3)" "unprognostic (2.29e-3)" "unprognostic (9.60e-2)" "prognostic favorable (2.06e-10)" "unprognostic (2.50e-1)" "unprognostic (9.49e-2)" "unprognostic (9.05e-2)" "unprognostic (1.51e-2)" 46.5 16.0 13.6 23.6 21.6 20.7 68.6 20.8 18.9 243.7 25.8 94.9 88.1 57.0 15.3 952.2 69.9 39.8 145.1 14.6 14.3 120.7 70.9 57.1 15.7 20.7 16.2 46.2 59.6 19.9 37.3 51.5 19.6 68.0 49.0 4.7 226.4 41.8 110.8 932.4 95.7 23.1 14.8 22.7 86.3 12.5 16.2 29.6 86.4 62.2 92.0 68.7 432.6 33.6 268.8 217.8 21.7 18.5 0.2 0.1 330.6 15.3 89.2 5.9 5.2 332.6 289.0 5.4 157.8 9.7 7.5 1090.1 31.6 242.4 1.0 0.6 74.2 11.6 165.1 74.4 34.7 7.3 113.6 0.5 538.6 0.9 43.9 64.2 96.1 7.0 99.6 94.0 0.0 342.6 1.9 96.5 42.3 3919.9 36.2 313.5 0.2 202.5 165.8 674.0 52.2 38.6 33.8 652.1 1.9 98.6 545.9 8.0 152.4 0.3 14.8 6.8 5.1 8.2 31.2 5.5 1.5 12.7 2.6 3.9 13.1 28.7 0.0 22.6 0.0 13.5 0.0 0.2 14.5 11.7 0.2 0.1 0.6 0.8 43.8 4.5 0.1 5.7 13.6 21.6 20.8 18.9 14.6 14.3 20.7 16.2 19.6 14.8 16.2 33.6 56.9 60.9 36.8 4.6 10.6 196.9 218.5 104.5 100.2 1.9 87.3 77.0 87.8 48.6 80.9 132.4 4.2 98.9 1.1 315.9 27.4 212.2 28.5 112.6 21.1 55.2 66.8 3.4 0.5 135.4 167.3 25.6 136.1 247.0 11.4 16.5 41.4 34.1 14.4 0.0 1.6 125.0 81.4 7.7 32.7 8.3 5.0 10.9 12.4 2.8 6.3 18.2 0.0 7.1 13.6 356.2 223.7 0.0 3.9 220.1 141.1 35.6 45.7 4.3 6.6 37.4 18.8 2.5 4.5 318.3 383.3 185.7 6.1 3.2 129.2 301.6 KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 355.5;Late spermatids: 228.7;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.0" "Group enriched" "Detected in many" 15 "B-cells: 1.1;dendritic cells: 4.0;T-cells: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA005539: AB_1078164, HPA056090: AB_2683034" "unprognostic (6.59e-2)" "unprognostic (3.33e-2)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (3.05e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" 42.6 9.6 49.0 9.5 52.7 1.5 31.2 42.3 47.5 40.9 61.8 49.2 12.1 62.2 13.0 64.6 31.7 15.2 88.2 45.1 44.9 31.6 101.9 13.6 7.6 51.6 44.9 22.1 28.3 9.4 27.9 25.8 48.3 42.5 14.9 11.0 29.9 31.8 66.4 51.8 23.6 37.4 47.6 6.9 25.9 15.4 48.4 9.4 30.8 39.9 11.8 70.1 52.3 48.9 5.9 12.2 4.0 72.0 57.8 21.9 19.9 37.1 25.8 3.1 3.7 30.2 2.5 46.2 8.9 46.0 7.0 12.3 15.7 30.4 5.3 22.7 8.3 0.1 17.0 96.0 8.1 11.2 0.0 12.6 41.6 3.2 35.6 13.2 31.2 1.6 2.4 56.4 23.1 14.4 4.5 46.9 5.3 8.9 9.0 1.7 7.9 8.6 24.5 36.1 1.8 0.0 3.6 10.9 50.9 33.3 7.1 8.7 46.1 8.4 3.2 10.8 17.1 9.8 61.9 0.2 5.6 21.1 15.8 0.0 0.1 0.0 0.1 0.1 0.0 0.8 1.3 0.4 0.4 1.1 2.4 0.8 0.0 0.1 0.0 4.0 1.7 0.5 49.0 52.7 42.3 47.5 45.1 44.9 51.6 44.9 48.3 47.6 48.4 48.9 18.3 12.8 34.2 355.5 4.9 23.1 102.1 11.4 37.0 22.2 16.8 18.0 94.1 24.3 8.1 18.4 41.7 89.2 15.7 8.3 7.9 11.6 102.3 14.2 15.4 21.9 18.0 9.1 12.1 7.9 6.8 21.8 7.7 13.1 1.3 38.5 23.6 70.0 13.3 0.0 29.0 12.8 4.1 6.9 6.5 228.7 32.3 3.3 23.2 60.9 1.2 6.5 0.0 322.7 191.4 9.6 7.5 20.7 10.7 50.5 17.6 13.6 7.0 20.2 26.3 129.9 24.0 28.4 25.6 36.2 25.7 66.2 4.7 6.9 26.0 63.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KANSL2 "C12orf41, FLJ20436, NSL2" ENSG00000139620 "KAT8 regulatory NSL complex subunit 2" Q9H9L4 12 48653211-48682238 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038497, HPA038498" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane, Cytosol" "HPA038497: AB_10674685, HPA038498: AB_2676046" "unprognostic (3.87e-3)" "unprognostic (6.18e-2)" "unprognostic (3.67e-1)" "unprognostic (8.89e-2)" "unprognostic (5.37e-2)" "unprognostic (4.73e-2)" "prognostic unfavorable (4.98e-4)" "unprognostic (5.46e-2)" "unprognostic (1.35e-3)" "unprognostic (6.16e-2)" "unprognostic (6.75e-3)" "unprognostic (4.19e-3)" "unprognostic (8.05e-2)" "unprognostic (2.92e-1)" "unprognostic (1.38e-1)" "unprognostic (1.18e-1)" "prognostic favorable (4.32e-4)" 11.9 11.4 6.0 8.2 7.0 41.8 12.2 8.6 8.0 13.9 7.3 11.8 8.1 14.1 11.5 13.3 12.6 7.7 13.4 6.5 6.9 12.2 9.8 10.9 13.9 7.0 6.5 16.3 9.7 12.2 9.3 12.2 6.7 11.1 9.3 11.8 13.0 8.3 40.7 13.4 11.9 9.8 6.7 13.2 10.8 14.6 6.8 14.2 11.5 23.1 13.8 12.4 12.8 8.8 19.5 26.5 21.8 12.8 25.6 22.0 48.1 20.8 17.6 35.9 19.5 45.2 25.1 31.9 39.0 25.5 14.0 18.3 37.1 23.5 29.5 30.4 22.5 37.1 20.2 12.9 29.2 40.0 13.9 20.8 31.2 25.5 46.2 18.0 17.2 24.8 43.7 20.9 25.0 18.7 39.2 29.2 28.6 28.1 26.0 33.4 21.3 35.9 17.2 27.1 25.1 17.6 43.2 30.0 25.7 21.8 40.2 43.4 12.8 25.5 18.9 10.9 19.7 29.8 50.7 46.2 12.4 89.5 13.6 35.3 19.7 23.5 25.1 21.2 23.7 27.3 23.9 25.9 25.8 23.8 27.9 26.9 9.0 24.3 23.0 20.2 32.2 24.0 6.0 7.0 8.6 8.0 6.5 6.9 7.0 6.5 6.7 6.7 6.8 8.8 18.0 3.2 14.3 9.8 24.7 11.9 14.7 17.9 32.5 15.6 15.7 15.5 10.9 8.6 15.0 14.7 29.2 22.5 36.5 10.2 9.8 13.3 24.4 8.2 13.9 13.7 9.0 14.1 11.5 9.8 12.5 15.1 12.2 12.4 11.4 19.8 14.6 9.6 11.9 15.2 13.8 9.1 10.2 11.9 13.2 13.8 12.5 13.7 16.0 7.5 14.8 8.2 11.3 15.1 18.8 12.2 4.7 10.1 16.9 12.1 10.8 15.6 10.2 22.8 26.3 15.7 16.6 38.5 34.8 19.9 11.2 25.3 30.6 15.9 12.4 9.8 KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 90.7;Cytotrophoblasts: 122.7;Extravillous trophoblasts: 143.3;Hofbauer cells: 89.5;Syncytiotrophoblasts: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 82000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 68.5 49.6 45.5 71.6 47.3 86.1 83.0 46.9 63.2 60.3 50.6 75.8 62.4 53.9 75.1 72.5 69.5 50.4 96.0 45.6 48.3 72.2 76.8 53.1 88.3 46.9 47.5 74.9 86.5 76.7 51.5 62.2 46.8 55.2 85.6 69.6 79.6 60.6 213.4 67.3 62.6 69.6 46.8 57.6 66.2 98.9 47.4 96.6 65.3 186.8 107.8 92.1 55.0 48.1 164.2 187.0 133.5 185.4 140.1 140.3 262.4 135.0 164.9 290.2 217.0 332.8 209.0 292.4 145.4 180.8 138.4 229.4 272.0 246.7 314.4 86.0 139.8 161.4 153.1 348.5 255.8 245.5 174.1 166.4 173.8 257.4 414.6 147.7 240.0 253.5 273.4 68.5 222.5 378.0 254.1 262.2 284.3 238.4 135.9 329.2 120.0 358.4 235.4 136.3 200.2 162.9 339.5 122.8 152.2 144.8 166.1 229.2 133.8 159.8 164.9 123.6 196.7 145.1 178.6 696.6 139.5 206.5 199.7 88.6 112.7 130.0 110.7 155.7 202.6 109.5 137.1 132.0 135.7 91.6 126.6 117.1 24.9 127.6 163.1 85.7 155.5 160.5 45.5 47.3 46.9 63.2 45.6 48.3 46.9 47.5 46.8 46.8 47.4 48.1 14.2 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.7 0.0 0.0 0.0 0.0 122.7 10.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 143.3 14.4 0.0 0.0 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 110.0 2.1 0.0 0.0 0.0 KATNB1 ENSG00000140854 "Katanin regulatory subunit B1" Q9BVA0 16 57735739-57757244 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 115.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041165, HPA041839" Enhanced Supported "Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" Microtubules "HPA041165: AB_10795584, HPA041839: AB_10795598" "unprognostic (1.37e-1)" "unprognostic (2.76e-2)" "unprognostic (1.56e-1)" "prognostic favorable (9.24e-4)" "unprognostic (2.54e-1)" "unprognostic (2.51e-1)" "prognostic unfavorable (3.93e-4)" "unprognostic (1.42e-1)" "unprognostic (2.92e-1)" "unprognostic (1.75e-1)" "prognostic favorable (8.44e-4)" "unprognostic (2.89e-2)" "unprognostic (1.03e-3)" "unprognostic (2.20e-1)" "unprognostic (1.29e-1)" "unprognostic (6.88e-2)" "unprognostic (1.54e-1)" 9.9 13.3 16.0 10.8 18.4 23.0 10.6 5.5 24.7 10.1 11.8 9.9 10.6 11.2 4.1 15.9 19.2 6.2 11.7 18.2 11.7 10.3 9.5 11.9 10.5 10.4 9.1 9.6 14.0 10.7 13.7 7.2 10.1 10.2 5.5 5.9 13.1 7.7 10.4 29.0 10.1 6.5 6.6 12.9 10.3 37.1 13.2 12.8 11.0 7.9 8.2 8.7 11.9 16.3 20.8 35.7 19.2 25.0 10.4 9.2 35.2 13.9 18.5 35.2 19.6 30.2 18.3 16.1 28.0 8.8 13.2 27.0 25.8 27.9 16.2 11.1 74.8 21.0 20.4 42.5 11.5 47.6 77.6 9.5 17.3 28.7 16.1 14.8 21.2 58.8 42.8 8.2 15.0 21.6 67.6 60.1 34.0 14.7 61.4 53.7 23.8 59.6 10.6 9.9 97.0 29.2 23.8 27.1 16.8 7.6 10.2 23.9 16.0 24.5 21.9 22.9 31.0 18.5 16.1 19.9 35.2 36.6 15.7 50.8 18.9 46.1 21.0 20.8 20.4 9.3 17.5 16.3 17.8 9.3 16.0 15.5 27.9 16.1 22.7 11.9 20.1 21.7 16.0 18.4 5.5 24.7 18.2 11.7 10.4 9.1 10.1 6.6 13.2 16.3 5.5 3.2 5.5 3.3 5.2 9.1 8.0 11.5 9.6 10.2 8.4 7.1 2.6 4.3 7.7 5.5 6.2 17.3 8.5 13.2 11.7 13.7 115.4 18.8 4.4 6.0 4.8 8.8 14.8 13.6 11.7 6.6 12.8 4.7 5.1 7.6 6.8 4.7 9.9 18.5 11.2 9.2 6.1 5.1 2.5 36.6 7.8 7.6 7.2 3.7 6.1 10.0 11.3 2.5 4.9 10.1 5.1 4.9 13.3 7.3 10.5 8.0 26.2 10.9 6.6 4.9 6.3 41.8 8.3 11.9 13.8 7.7 10.9 8.2 11.8 7.8 KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.5;Cytotrophoblasts: 3.0;dendritic cells: 1.4;Extravillous trophoblasts: 2.6;Hofbauer cells: 2.6;Syncytiotrophoblasts: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 9.9;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035089, HPA035090" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Plasma membrane" "HPA035089: AB_10671509, HPA035090: AB_10601129" "unprognostic (1.81e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" "unprognostic (3.65e-3)" "unprognostic (7.76e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.72e-2)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.12e-1)" "unprognostic (1.47e-3)" "unprognostic (2.98e-1)" "unprognostic (2.11e-1)" "unprognostic (1.50e-3)" "unprognostic (1.45e-1)" 4.4 4.8 5.2 4.7 5.9 6.7 5.4 3.9 6.9 6.3 22.7 6.5 4.8 6.3 6.2 9.7 29.7 5.1 5.4 5.4 4.1 7.8 4.0 6.3 4.4 6.7 7.8 5.1 9.0 7.7 11.5 4.4 4.9 8.8 7.2 31.3 7.9 5.7 3.3 8.9 6.0 5.5 4.9 6.2 9.3 9.9 6.3 5.6 15.9 1.7 4.0 5.3 5.8 6.6 6.7 13.5 7.5 7.0 11.1 10.1 12.4 8.9 9.6 7.7 10.4 12.0 10.9 5.7 12.4 12.8 15.0 11.0 9.7 11.5 15.4 26.5 6.7 4.5 14.9 7.0 6.6 6.1 11.0 10.8 9.9 17.1 18.2 10.0 15.5 6.3 7.3 4.7 11.1 15.3 6.7 7.5 4.6 8.6 5.5 9.6 9.1 6.2 14.5 9.2 9.5 6.1 8.9 7.9 5.0 10.3 17.8 5.3 13.5 9.8 6.2 7.7 7.9 6.3 5.7 6.4 11.3 5.9 8.9 14.3 1.8 3.6 0.7 1.2 0.7 0.8 0.4 1.2 1.2 1.1 1.6 0.3 9.9 5.0 0.4 1.4 1.6 0.3 5.2 5.9 3.9 6.9 5.4 4.1 6.7 7.8 4.9 4.9 6.3 6.6 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 3.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.4 0.0 0.0 0.0 KCNAB1 "AKR6A3, hKvb3, hKvBeta3, KCNA1B, Kvb1.3" ENSG00000169282 "Potassium voltage-gated channel subfamily A member regulatory beta subunit 1" Q14722 3 156037701-156539138 "Predicted intracellular proteins, Transporters" "Ion transport, Potassium transport, Transport" "Ion channel, Oxidoreductase, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 52.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 85.8;Excitatory neurons: 108.6;Inhibitory neurons: 605.4;Oligodendrocyte precursor cells: 206.6;Oligodendrocytes: 97.5;Sertoli cells: 78.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 7.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HEL: 3.4;hTEC/SVTERT24-B: 5.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036110, HPA044550" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Nucleoplasm, Plasma membrane" "HPA036110: , HPA044550: AB_10797032" "unprognostic (1.52e-1)" "unprognostic (3.73e-1)" "unprognostic (1.33e-1)" "unprognostic (2.98e-4)" "unprognostic (1.24e-2)" "unprognostic (1.64e-1)" "unprognostic (1.81e-1)" "unprognostic (2.83e-2)" "unprognostic (8.51e-2)" "unprognostic (3.72e-2)" "unprognostic (5.87e-2)" "unprognostic (9.70e-2)" "unprognostic (2.17e-3)" "unprognostic (2.60e-1)" "unprognostic (1.95e-1)" "unprognostic (1.06e-1)" "unprognostic (4.00e-1)" 15.8 6.3 12.7 1.2 52.7 1.6 7.3 15.5 17.3 8.4 4.2 4.1 1.7 5.4 12.8 2.2 4.3 2.9 5.5 25.9 11.6 1.8 2.6 3.3 0.9 7.2 12.1 2.9 4.0 2.0 1.8 1.3 7.2 22.4 1.8 12.8 3.9 19.2 2.0 2.2 2.7 2.7 8.4 5.2 1.6 3.1 14.1 1.8 28.7 5.1 0.3 2.9 5.0 15.4 0.5 0.5 0.7 0.2 0.0 0.0 1.4 1.2 0.0 0.0 0.1 0.9 0.1 0.4 0.7 0.0 0.3 0.3 0.0 0.0 0.0 0.4 1.0 3.4 0.6 1.6 0.0 1.0 0.2 0.0 0.0 5.2 0.0 1.1 2.1 0.5 0.1 0.3 0.2 0.1 0.3 0.6 1.1 1.5 0.2 0.6 0.7 2.8 0.0 0.2 0.8 0.8 0.3 0.6 0.7 0.5 0.8 0.5 2.2 0.8 0.5 1.4 1.2 1.8 0.4 0.4 2.6 1.1 1.0 0.8 0.1 0.0 0.4 0.2 0.8 0.2 0.4 0.3 0.2 0.2 0.3 0.3 0.0 0.3 0.3 1.2 0.5 0.1 12.7 52.7 15.5 17.3 25.9 11.6 7.2 12.1 7.2 8.4 14.1 15.4 7.2 0.0 0.0 7.5 0.7 0.8 0.3 0.0 0.0 85.8 1.4 1.4 4.3 0.0 0.7 0.0 31.3 0.1 0.5 0.1 0.0 0.4 13.7 0.6 2.4 2.8 0.0 0.0 108.6 0.0 0.0 3.8 0.0 2.1 0.0 0.4 0.7 0.0 4.6 0.0 605.4 0.0 0.0 11.1 1.0 7.0 0.0 1.2 1.8 24.4 0.0 2.7 0.0 206.6 97.5 0.0 0.0 2.6 2.3 0.2 0.0 0.1 0.0 6.7 78.9 1.3 73.3 0.3 4.2 1.2 0.9 0.1 0.5 0.2 0.0 0.2 KCNB2 Kv2.2 ENSG00000182674 "Potassium voltage-gated channel subfamily B member 2" Q92953 8 72537225-72938349 "FDA approved drug targets, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.6;lymphoid tissue: 2.3;retina: 4.6" "Group enriched" "Detected in some" 14 "Cone photoreceptor cells: 264.8;Excitatory neurons: 279.1;Inhibitory neurons: 241.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 1.4;HDLM-2: 1.4;HEK 293: 3.4;SCLC-21H: 2.7" "Low region specificity" "Detected in many" HPA065970 Approved "Nucleoli,Plasma membrane,Midbody" Yes NA "Cluster 58: Brain - Synaptic function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoli, Midbody" "HPA065970: AB_2685591" "unprognostic (9.87e-3)" "unprognostic (1.71e-1)" "unprognostic (7.57e-2)" "unprognostic (1.10e-3)" "unprognostic (1.22e-1)" "unprognostic (1.34e-1)" "unprognostic (1.44e-2)" "unprognostic (2.72e-1)" "unprognostic (6.93e-5)" "unprognostic (5.53e-3)" "unprognostic (3.30e-2)" "unprognostic (1.62e-1)" "unprognostic (3.35e-2)" "unprognostic (3.26e-1)" 0.1 0.4 1.7 0.0 2.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 2.4 2.2 0.0 0.0 0.0 0.0 1.0 2.6 0.0 0.5 0.0 1.1 0.0 0.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.3 0.0 1.3 2.3 0.4 0.3 1.5 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 1.4 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.0 1.4 2.4 2.2 1.0 2.6 0.4 1.3 1.5 0.0 0.1 0.0 0.0 4.6 0.0 0.0 0.0 0.0 1.2 17.4 0.0 0.0 0.3 0.0 0.0 1.8 264.8 0.0 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 17.9 0.0 279.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 241.2 0.6 0.0 0.0 0.0 6.8 1.2 0.0 0.0 3.7 0.0 0.7 0.0 11.6 4.7 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.1 0.1 0.4 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 70.5;stomach 1: 56.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 41.8;granulocytes: 33.7;Hofbauer cells: 40.6;Kupffer cells: 104.0;Macrophages: 37.8;monocytes: 59.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 48 "basophil: 51.4;classical monocyte: 38.5;eosinophil: 23.4;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.1;non-classical monocyte: 36.6" "Group enriched" "Detected in many" 115 "dendritic cells: 18.3;granulocytes: 53.1;monocytes: 41.8" "Cell line enhanced" "Detected in some" "HEL: 70.3;NB-4: 44.7;OE19: 155.3;THP-1: 32.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014849 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" 7.3 2.8 2.8 20.7 2.9 8.2 5.2 2.5 3.6 9.9 7.0 34.9 70.5 8.8 1.9 4.6 9.4 24.6 5.0 3.0 3.0 20.1 5.0 13.8 5.0 3.8 3.6 14.0 10.8 3.6 3.1 12.7 3.6 8.0 47.3 8.1 15.4 3.4 1.3 1.3 40.0 11.1 3.3 12.6 56.2 1.8 4.1 1.9 33.5 3.0 3.2 6.2 4.5 4.9 0.1 0.1 0.1 0.2 8.1 2.1 7.1 0.1 0.0 1.0 0.8 23.0 2.0 0.3 21.3 0.1 0.1 0.3 1.8 0.0 0.7 0.0 0.2 70.3 0.4 4.7 2.9 0.6 12.0 7.1 0.0 0.6 0.0 0.3 0.3 0.1 1.9 0.3 0.8 0.1 0.1 44.7 0.9 155.3 0.1 7.6 0.3 0.5 1.7 0.0 0.0 0.4 0.1 0.0 0.0 5.4 0.1 32.7 0.1 0.1 0.2 0.2 0.1 0.3 0.3 0.4 0.1 12.9 0.1 51.4 38.5 23.4 0.1 41.8 0.2 0.2 0.1 0.1 18.3 0.3 0.1 0.1 53.1 0.2 36.6 0.7 0.0 13.2 2.8 2.9 2.5 3.6 3.0 3.0 3.8 3.6 3.6 3.3 4.1 4.9 4.4 0.0 6.8 0.3 0.7 0.3 0.6 1.1 3.4 0.2 0.2 0.3 0.7 8.6 5.6 1.8 0.0 0.4 0.0 8.6 3.9 0.5 0.1 3.1 3.4 8.9 2.4 2.1 0.2 7.3 7.4 4.5 41.8 5.0 33.7 0.2 5.7 2.0 40.6 0.0 0.3 27.9 4.1 104.0 2.9 0.3 3.7 37.8 0.0 8.4 59.0 22.7 1.0 0.0 0.0 3.3 8.9 2.6 0.2 0.4 8.6 23.4 4.6 1.2 0.0 4.7 0.7 0.0 0.4 2.7 0.1 2.1 1.0 8.8 44.3 0.6 KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218667-84239750 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 3.4;retina: 4.3" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 56.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA063516: " "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" 0.1 0.4 0.6 0.0 1.0 0.3 0.0 3.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.1 3.4 1.5 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.3 0.0 0.0 0.1 0.3 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.6 1.0 3.3 0.4 0.5 0.7 3.4 1.5 2.4 1.3 0.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 56.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;pituitary gland: 10.7" "Group enriched" "Detected in some" 63 "Oligodendrocyte precursor cells: 331.7;Oligodendrocytes: 989.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "HAP1: 1.0;OE19: 1.9;SH-SY5Y: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.0 1.8 7.3 0.3 11.9 0.2 0.5 6.5 16.0 0.3 2.8 0.6 0.4 0.1 0.1 0.1 0.2 0.4 0.2 6.4 8.8 0.1 0.1 0.0 0.8 8.4 8.8 0.0 1.5 0.1 10.7 0.0 8.2 0.7 0.5 3.4 1.1 0.2 0.0 0.4 1.1 0.1 5.8 1.1 1.4 1.7 9.7 0.4 0.2 0.0 0.7 0.1 0.3 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 7.3 11.9 6.5 16.0 6.4 8.8 8.4 8.8 8.2 5.8 9.7 15.4 0.0 0.0 0.0 2.0 9.7 0.5 1.6 0.0 0.0 4.2 1.1 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 3.2 0.1 0.1 0.1 3.6 0.0 9.3 0.6 0.0 0.1 2.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 10.4 1.5 0.0 0.0 0.0 1.9 0.0 0.1 3.6 1.0 0.0 3.4 0.0 331.7 989.4 0.5 0.2 0.0 0.1 1.5 0.0 0.0 0.0 1.0 0.0 0.2 0.5 1.2 3.4 0.0 0.0 0.1 0.3 0.1 0.6 0.4 KCNJ15 "IRKK, Kir1.3, Kir4.2" ENSG00000157551 "Potassium inwardly rectifying channel subfamily J member 15" Q99712 21 38155549-38307357 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 241.6;thyroid gland: 129.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 60.9;Alveolar cells type 2: 197.9;Cholangiocytes: 88.6;Proximal tubular cells: 236.9" "Cancer enhanced" "Detected in many" "thyroid cancer: 29.6" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 20 "neutrophil: 395.3" "Lineage enriched" "Detected in many" 20 "granulocytes: 395.3" "Cell line enhanced" "Detected in many" "ASC TERT1: 68.7;GAMG: 103.6;HBEC3-KT: 69.6;RPTEC TERT1: 67.5;RT4: 80.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA016702 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Vesicles, Cytosol" "HPA016702: AB_1855560" "unprognostic (6.34e-2)" "unprognostic (5.04e-2)" "unprognostic (7.92e-2)" "unprognostic (2.07e-3)" "unprognostic (1.21e-1)" "unprognostic (3.54e-3)" "unprognostic (2.72e-3)" "unprognostic (3.03e-2)" "unprognostic (6.79e-2)" "unprognostic (2.89e-3)" "unprognostic (3.77e-2)" "unprognostic (1.95e-2)" "prognostic favorable (4.09e-10)" "unprognostic (9.46e-3)" "unprognostic (1.82e-1)" "unprognostic (5.27e-2)" "prognostic favorable (1.95e-4)" 8.7 0.5 0.8 20.7 0.7 14.1 2.8 0.9 6.7 12.7 0.5 0.9 1.5 0.5 11.0 8.5 1.2 30.4 0.8 0.8 0.6 241.6 2.8 42.2 1.2 0.9 0.6 0.3 57.8 0.7 0.4 4.6 1.8 2.6 0.4 0.5 25.5 14.6 0.5 3.0 0.7 2.4 0.3 11.7 40.5 1.8 5.4 1.9 129.5 3.0 1.9 25.1 8.1 1.1 1.6 0.0 0.3 0.6 13.7 68.7 0.6 1.0 4.8 0.0 0.0 0.0 0.6 0.2 0.0 7.5 103.6 23.5 0.0 69.6 0.6 0.0 0.0 0.0 0.5 0.3 0.0 0.2 0.1 21.0 7.2 17.8 3.8 1.5 3.2 0.1 0.2 0.7 31.6 0.0 0.1 0.2 0.0 0.1 0.7 1.5 0.3 0.7 67.5 80.2 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.5 0.0 1.5 0.4 3.5 0.2 1.7 0.4 0.1 5.6 4.3 0.4 0.3 19.3 0.1 0.0 0.8 0.0 0.0 0.1 0.0 1.2 0.0 0.2 0.3 395.3 0.0 0.0 0.4 0.0 4.6 0.8 0.7 0.9 6.7 0.8 0.6 0.9 0.6 1.8 0.3 5.4 1.1 2.9 60.9 197.9 0.0 1.1 2.8 10.4 20.7 13.6 0.0 0.5 0.0 1.6 88.6 33.1 31.3 0.0 0.1 0.0 0.0 17.6 27.8 1.9 0.0 0.0 4.6 0.0 0.0 0.3 8.6 0.8 1.5 15.8 0.1 6.3 0.0 0.7 0.4 0.4 0.0 0.1 0.0 2.0 2.9 3.0 2.2 0.6 5.9 1.8 0.0 2.1 0.0 0.0 0.0 0.1 44.7 0.0 0.0 0.1 0.7 0.0 236.9 7.0 0.0 0.0 1.5 0.8 1.1 1.1 16.8 1.6 0.1 1.7 0.1 0.0 9.0 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KCNK13 "K2p13.1, THIK-1, THIK1" ENSG00000152315 "Potassium two pore domain channel subfamily K member 13" Q9HB14 14 90061994-90185853 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "choroid plexus: 5.6;parathyroid gland: 6.0;testis: 9.2" "Cell type enriched" "Detected in some" 4 "Microglial cells: 41.2" "Cancer enhanced" "Detected in many" "testis cancer: 5.3" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "myeloid DC: 1.2" "Lineage enhanced" "Detected in single" "dendritic cells: 1.2" "Cell line enhanced" "Detected in some" "GAMG: 1.0;RT4: 1.9;SuSa: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA003514 Approved Approved "Nuclear speckles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 15: RT4 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles, Cell Junctions" "HPA003514: AB_2666978" "unprognostic (1.40e-1)" "unprognostic (1.73e-1)" "unprognostic (6.17e-2)" "unprognostic (6.31e-2)" "unprognostic (2.56e-1)" "unprognostic (5.55e-2)" "unprognostic (3.56e-2)" "unprognostic (3.98e-2)" "unprognostic (2.40e-1)" "unprognostic (2.34e-1)" "unprognostic (1.85e-1)" "unprognostic (3.45e-2)" "unprognostic (1.97e-1)" "unprognostic (2.04e-2)" "unprognostic (6.32e-2)" "unprognostic (1.46e-1)" "unprognostic (5.65e-2)" 0.3 0.8 1.7 1.7 1.5 0.0 0.2 0.9 1.9 0.1 5.6 0.4 0.5 0.2 1.0 0.2 0.3 0.4 1.6 1.6 1.4 3.9 0.5 0.4 0.6 1.6 2.3 0.1 0.3 6.0 0.3 0.2 1.8 0.1 0.5 0.0 0.2 0.4 0.0 0.1 0.5 0.3 1.8 0.6 0.4 9.2 2.2 1.1 1.9 0.0 0.5 0.5 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.4 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.1 1.9 0.7 0.2 0.0 0.7 0.5 2.9 0.0 0.7 0.0 0.0 0.8 0.0 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 1.7 1.5 0.9 1.9 1.6 1.4 1.6 2.3 1.8 1.8 2.2 3.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.6 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 2.8 0.4 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 6.3 0.0 0.4 0.0 0.0 6.0 0.0 4.4 0.0 0.0 4.0 8.1 0.6 0.0 3.2 0.0 41.2 9.0 0.0 0.0 3.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.6 0.0 0.3 0.1 0.1 0.4 0.0 0.1 KCNK17 "K2p17.1, TALK-2, TALK2, TASK-4, TASK4" ENSG00000124780 "Potassium two pore domain channel subfamily K member 17" Q96T54 6 39299001-39314461 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 7.7;thyroid gland: 6.5" "Cell type enhanced" "Detected in some" "dendritic cells: 11.0;Exocrine glandular cells: 7.9;granulocytes: 6.3;Microglial cells: 17.8;Smooth muscle cells: 5.4" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 34 "plasmacytoid DC: 63.8" "Lineage enriched" "Detected in many" 34 "dendritic cells: 63.8" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 83.8" "Not detected" "Not detected" HPA043892 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA043892: AB_10962838" "unprognostic (5.33e-3)" "unprognostic (6.42e-2)" "unprognostic (1.33e-1)" "unprognostic (1.04e-1)" "unprognostic (1.54e-1)" "unprognostic (3.70e-2)" "unprognostic (3.85e-2)" "unprognostic (4.09e-2)" "unprognostic (4.95e-1)" "unprognostic (2.35e-1)" "unprognostic (1.71e-2)" "unprognostic (2.54e-1)" "unprognostic (3.77e-11)" "unprognostic (5.89e-2)" "unprognostic (5.36e-1)" "unprognostic (2.82e-1)" "unprognostic (3.86e-3)" 0.5 0.3 0.3 0.4 0.4 1.2 0.8 0.3 0.6 0.7 0.2 0.6 1.9 1.2 0.0 0.3 0.8 2.5 5.8 0.2 0.3 0.1 4.0 7.7 0.7 0.4 0.5 0.2 3.9 0.1 1.8 4.0 0.3 0.6 0.5 0.0 0.7 0.2 0.1 0.1 1.1 1.0 0.2 0.7 2.9 0.2 0.5 1.3 6.5 0.5 1.1 0.7 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 83.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.8 0.0 63.8 0.0 0.3 0.3 0.4 0.3 0.6 0.2 0.3 0.4 0.5 0.3 0.2 0.5 0.3 0.0 0.0 2.6 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.9 0.3 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.1 7.9 0.0 1.8 1.1 0.1 6.3 0.0 0.7 0.2 0.1 0.0 0.1 0.4 0.0 0.6 0.0 0.0 0.0 0.9 0.0 17.8 0.2 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 KCNK6 "K2p6.1, TWIK-2" ENSG00000099337 "Potassium two pore domain channel subfamily K member 6" Q9Y257 19 38319845-38332076 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 151.3;Urothelial cells: 131.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 26.2" "Group enriched" "Detected in many" 6 "dendritic cells: 11.4;granulocytes: 26.2;monocytes: 7.2" "Cell line enhanced" "Detected in many" "HEL: 37.6;HMC-1: 40.3;T-47d: 22.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB022637, HPA040184" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Actin filaments" "CAB022637: , HPA040184: AB_2676876" "unprognostic (7.98e-2)" "unprognostic (2.57e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.45e-6)" "unprognostic (3.76e-1)" "unprognostic (6.88e-2)" "unprognostic (1.87e-1)" "unprognostic (3.08e-2)" "unprognostic (4.31e-1)" "unprognostic (4.91e-1)" "unprognostic (4.10e-3)" "unprognostic (3.15e-1)" "prognostic unfavorable (1.04e-5)" "unprognostic (1.07e-2)" "unprognostic (3.46e-1)" "unprognostic (5.88e-2)" "unprognostic (4.59e-3)" 3.9 2.4 2.9 7.5 2.4 3.9 5.6 3.0 3.3 29.9 2.7 15.4 4.6 24.0 1.5 30.5 15.7 4.5 6.7 2.7 2.2 3.1 3.0 9.4 5.6 2.9 2.3 9.5 12.5 0.6 1.9 7.0 2.9 6.2 9.4 0.8 14.5 2.4 1.5 19.1 6.8 14.3 2.1 15.6 9.5 2.1 2.8 2.5 1.4 0.7 7.9 13.3 18.2 3.7 9.2 3.3 0.5 0.5 5.1 3.3 0.7 7.8 3.8 2.0 2.7 2.6 9.8 0.6 3.5 11.2 2.1 11.7 4.2 17.7 1.3 0.4 0.3 37.6 1.9 0.4 4.7 2.7 40.3 0.8 15.6 2.5 4.8 10.5 5.3 5.8 0.5 2.8 5.7 20.2 2.4 2.3 0.4 19.4 2.1 3.9 0.5 2.7 7.1 0.8 0.5 0.8 0.8 0.8 0.3 1.8 22.8 10.5 5.8 0.5 4.4 4.1 0.4 1.0 0.2 1.0 0.6 13.4 0.3 26.2 6.9 15.8 1.4 6.2 1.2 1.4 2.0 1.9 11.4 1.1 1.7 1.2 5.0 0.6 7.2 3.1 2.6 2.3 2.9 2.4 3.0 3.3 2.7 2.2 2.9 2.3 2.9 2.1 2.8 3.7 8.7 0.0 10.5 0.0 16.0 43.1 50.6 20.6 20.5 3.3 61.2 32.9 12.1 17.2 15.1 7.3 6.2 2.0 18.5 62.4 0.0 19.1 2.8 32.5 58.8 28.3 12.6 17.9 1.1 47.7 4.0 19.2 28.1 84.8 22.2 72.7 151.3 4.3 39.2 0.0 1.7 64.5 2.0 75.7 61.5 1.2 25.7 47.0 5.4 2.8 62.1 1.2 11.3 0.0 0.9 67.2 39.2 20.3 45.6 41.1 37.6 0.4 7.7 5.9 26.3 3.1 9.3 14.8 3.3 48.0 67.2 2.5 14.8 1.5 26.7 131.5 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 16.0;Inhibitory neurons: 8.0;Late spermatids: 9.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 4 "cerebellum: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA075842: " "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.96e-8)" "unprognostic (1.91e-1)" "unprognostic (8.17e-3)" "unprognostic (2.19e-3)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (5.12e-6)" "unprognostic (2.94e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" "unprognostic (1.76e-1)" 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.8 1.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.9 0.2 0.1 0.8 0.3 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.3 2.1 0.0 0.0 0.0 0.0 0.0 16.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.8;brain: 20.8;liver: 31.3" "Cell type enhanced" "Detected in some" "Astrocytes: 36.2;Excitatory neurons: 149.9;Inhibitory neurons: 97.0;Oligodendrocyte precursor cells: 63.3" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 17.5;NTERA-2: 6.4;SK-MEL-30: 12.9;THP-1: 21.8;U-937: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" 0.4 27.8 7.8 0.2 10.8 0.0 0.5 11.3 14.0 2.0 2.2 1.4 0.3 2.9 0.3 0.2 0.4 0.4 6.8 20.8 7.5 3.9 31.3 2.3 0.4 11.1 4.7 0.7 4.5 0.4 7.6 0.0 6.7 9.6 0.7 2.5 0.5 4.3 9.5 1.3 0.3 2.0 9.0 0.5 0.7 3.0 8.2 0.2 0.3 6.7 0.2 2.3 1.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 2.1 17.5 2.7 0.3 0.0 0.0 0.2 0.0 0.5 0.0 2.3 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.2 0.0 0.3 0.0 1.4 6.4 0.0 0.0 0.0 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.2 12.9 0.4 0.3 21.8 0.3 0.0 0.5 1.8 0.0 0.1 0.0 0.1 2.0 7.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 10.8 11.3 14.0 20.8 7.5 11.1 4.7 6.7 9.0 8.2 11.1 1.4 0.0 1.1 36.2 0.0 0.3 0.3 0.0 0.0 7.9 0.6 1.3 15.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 8.2 0.0 0.0 149.9 0.9 0.0 0.8 0.0 1.3 0.0 0.8 5.0 18.3 0.0 0.0 97.0 1.0 0.0 1.0 0.3 0.5 0.0 0.1 21.4 6.5 0.0 0.4 0.0 63.3 9.2 1.0 0.1 0.0 1.2 4.7 0.0 0.7 0.0 7.8 0.0 0.1 0.3 0.3 6.5 0.3 0.3 0.0 0.0 0.2 0.5 0.6 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCNS3 Kv9.3 ENSG00000170745 "Potassium voltage-gated channel modifier subfamily S member 3" Q9BQ31 2 17877847-18361616 "Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "lung: 23.5;skeletal muscle: 86.0;tongue: 45.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 28.9;Enteroendocrine cells: 32.5;Theca cells: 30.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 69.2;RPMI-8226: 28.9;RT4: 48.2;U-266/84: 34.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014864 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA014864: AB_1852155" "unprognostic (5.62e-2)" "unprognostic (4.27e-3)" "unprognostic (6.87e-2)" "unprognostic (1.68e-1)" "unprognostic (3.19e-1)" "unprognostic (1.64e-2)" "unprognostic (3.30e-1)" "unprognostic (9.47e-3)" "unprognostic (9.06e-2)" "unprognostic (8.45e-2)" "unprognostic (5.82e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (1.53e-4)" "unprognostic (1.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.67e-1)" "unprognostic (4.71e-2)" 2.9 1.1 2.6 3.8 2.9 0.0 6.2 3.9 4.0 7.8 9.5 12.5 3.7 3.2 2.6 6.0 3.9 5.4 6.6 2.9 4.2 5.0 3.8 23.5 0.6 10.5 7.9 1.0 9.8 2.9 1.2 11.0 12.5 6.5 5.0 0.4 11.2 3.1 86.0 5.6 5.4 3.3 5.3 1.0 9.5 3.9 4.3 1.4 2.3 45.5 2.0 6.8 6.3 4.4 8.5 1.4 0.7 0.0 1.6 0.8 3.8 2.8 8.5 1.7 2.0 0.1 17.1 0.0 0.9 3.0 1.9 2.7 20.7 0.1 1.8 0.0 5.7 0.0 0.2 0.1 8.1 0.2 0.7 0.7 12.9 0.1 1.2 15.5 0.4 3.9 0.4 0.0 1.0 2.2 0.0 0.0 10.2 11.5 0.2 2.4 69.2 28.9 1.8 48.2 20.3 0.7 0.0 5.3 6.1 4.8 2.8 0.0 0.2 2.7 0.0 0.2 21.6 0.1 34.9 0.1 15.2 0.0 20.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 3.9 4.0 2.9 4.2 10.5 7.9 12.5 5.3 4.3 4.4 3.8 28.9 8.2 0.0 0.0 13.9 16.8 6.9 21.1 0.2 11.5 7.0 0.5 18.6 6.8 11.0 0.0 0.6 0.0 10.9 0.0 21.5 0.3 0.9 0.6 5.9 32.5 0.0 0.3 0.4 3.5 12.1 8.2 0.9 1.3 4.3 2.5 5.4 0.5 0.0 16.9 5.6 14.2 0.0 4.5 1.2 1.5 0.4 21.4 1.9 0.7 0.1 0.0 7.1 2.5 2.4 4.9 3.8 1.2 13.6 4.1 5.5 1.7 0.2 6.6 13.5 10.6 0.3 3.4 8.0 5.8 0.8 0.6 30.6 10.3 7.1 KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 7.5" "Group enriched" "Detected in some" 15 "Early spermatids: 61.1;Late spermatids: 24.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 7.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KEL "CD238, ECE3" ENSG00000197993 "Kell metallo-endopeptidase (Kell blood group)" P23276 7 142941114-142962363 "Blood group antigen proteins, Cancer-related genes, CD markers, Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Blood group antigen, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 56.3;testis: 32.3" "Cell type enhanced" "Detected in some" "Erythroid cells: 79.7;Oligodendrocytes: 30.1;Squamous epithelial cells: 16.8" "Cancer enhanced" "Detected in some" "testis cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "HEL: 31.7;K-562: 26.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA064442 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Golgi apparatus, Plasma membrane" "Nucleoplasm, Cytosol" "HPA064442: " "unprognostic (5.78e-3)" "unprognostic (1.08e-5)" "unprognostic (5.29e-3)" "unprognostic (4.85e-3)" "unprognostic (9.68e-2)" "unprognostic (1.96e-2)" "unprognostic (1.03e-1)" "unprognostic (1.54e-2)" "unprognostic (5.18e-2)" "unprognostic (1.08e-2)" "unprognostic (3.71e-2)" "unprognostic (3.57e-2)" "unprognostic (2.29e-3)" "unprognostic (9.24e-2)" "unprognostic (7.05e-2)" "unprognostic (3.32e-2)" "unprognostic (3.25e-3)" 0.2 0.0 1.8 0.8 2.7 56.3 0.3 1.7 2.2 0.9 1.4 0.1 0.0 0.2 0.0 0.8 0.5 0.0 0.3 2.0 1.5 0.6 0.3 0.5 10.6 2.5 2.2 0.2 0.2 0.0 0.2 0.4 2.4 0.3 0.0 0.1 0.6 0.1 0.2 0.1 0.9 0.0 1.9 4.9 0.2 32.3 2.4 1.3 0.3 0.0 6.7 0.1 0.4 2.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 31.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.1 0.5 0.1 0.6 0.0 0.0 0.1 0.0 0.2 0.0 1.4 0.0 0.2 0.0 0.0 0.3 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 2.7 1.7 2.2 2.0 1.5 2.5 2.2 2.4 1.9 2.4 2.8 0.2 0.0 0.0 0.3 0.0 0.0 1.3 0.2 4.0 0.0 0.3 0.1 0.4 0.0 1.4 3.7 0.0 0.1 0.1 0.0 1.9 0.3 2.4 0.2 0.1 0.1 0.0 79.7 3.0 0.0 0.2 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 30.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 3.1 0.0 1.4 0.2 16.8 0.0 0.1 0.0 0.0 0.0 0.9 KIAA0895 ENSG00000164542 KIAA0895 Q8NCT3 7 36324152-36390125 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 22.3" "Cell type enhanced" "Detected in many" "Early spermatids: 87.9;Endometrial ciliated cells: 41.8;Late spermatids: 65.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 38.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021036, HPA061066" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Plasma membrane, Cell Junctions, Cytosol" "HPA021036: AB_2670571, HPA061066: AB_2684423" "unprognostic (4.94e-2)" "unprognostic (9.59e-2)" "unprognostic (2.93e-1)" "unprognostic (1.39e-1)" "unprognostic (8.85e-2)" "unprognostic (1.15e-3)" "unprognostic (3.79e-3)" "unprognostic (3.43e-1)" "unprognostic (3.74e-1)" "unprognostic (4.71e-3)" "unprognostic (1.46e-1)" "unprognostic (3.49e-1)" "unprognostic (4.51e-2)" "unprognostic (6.68e-2)" "unprognostic (3.06e-2)" "unprognostic (2.35e-2)" "unprognostic (5.24e-2)" 1.1 8.1 5.3 0.7 5.8 2.4 3.7 14.2 5.2 2.3 10.5 2.5 1.8 3.0 6.2 2.3 5.8 3.1 1.7 5.3 8.7 9.2 5.5 3.0 0.2 4.1 5.0 8.6 9.1 11.6 6.3 1.2 3.9 2.9 1.3 15.0 2.8 2.6 1.5 5.8 1.1 2.9 3.7 0.6 11.1 22.3 6.0 3.2 3.6 1.4 0.4 1.3 1.1 5.0 10.7 6.3 13.2 12.4 0.4 0.3 2.9 2.8 3.3 6.5 7.5 2.8 5.5 0.1 3.0 0.7 11.0 6.1 18.1 5.6 5.4 0.9 10.1 0.2 9.7 2.5 2.3 1.9 0.4 1.5 9.5 6.0 7.0 7.7 0.2 5.8 4.4 0.2 0.6 3.8 6.0 4.0 0.6 2.6 1.5 2.2 0.5 0.0 13.8 1.3 38.1 13.6 4.8 12.5 4.0 9.0 11.8 1.5 0.0 0.8 3.2 1.8 4.2 6.2 14.6 0.1 2.4 0.5 2.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 5.3 5.8 14.2 5.2 5.3 8.7 4.1 5.0 3.9 3.7 6.0 5.0 1.5 6.4 2.7 7.5 1.4 9.7 5.1 3.5 17.6 17.8 13.3 8.1 3.7 5.7 3.7 3.7 27.1 2.3 0.9 0.9 5.9 5.0 87.9 41.8 2.2 1.6 8.4 0.8 22.4 2.9 1.2 2.1 11.2 13.3 1.3 8.3 0.4 5.6 0.5 11.8 25.9 1.5 0.0 0.0 0.4 65.4 2.8 0.4 3.6 1.0 0.1 5.7 0.0 12.1 13.1 3.9 1.7 0.4 3.2 3.0 0.2 10.0 25.9 16.3 6.6 5.7 2.1 28.8 11.9 4.7 8.7 0.7 1.2 7.6 1.6 2.0 KIAA1522 ENSG00000162522 KIAA1522 Q9P206 1 32741830-32774970 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 154.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 125.7;hTCEpi: 103.0;RT4: 117.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032050, HPA032051, HPA064839" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA032050: AB_10601764, HPA032051: AB_2674126, HPA064839: AB_2685366" "unprognostic (7.98e-2)" "unprognostic (1.14e-2)" "unprognostic (1.44e-2)" "unprognostic (3.09e-2)" "unprognostic (6.41e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (6.29e-7)" "unprognostic (1.58e-1)" "unprognostic (1.13e-1)" "unprognostic (5.06e-2)" "prognostic unfavorable (8.25e-5)" "unprognostic (4.55e-2)" "prognostic favorable (1.29e-5)" "unprognostic (1.35e-2)" "unprognostic (1.35e-1)" "unprognostic (3.98e-1)" "unprognostic (2.12e-1)" 7.9 93.0 14.6 7.0 10.7 1.2 24.3 1.8 15.6 14.5 27.1 42.5 51.7 10.1 12.2 76.7 23.5 16.0 5.1 12.4 6.5 43.9 12.0 18.2 1.2 5.2 5.5 22.3 70.7 37.8 9.1 8.4 4.3 40.9 30.9 1.2 68.3 20.2 3.1 74.1 45.9 6.7 4.2 1.4 61.8 5.1 7.7 8.2 39.4 3.2 12.1 22.2 28.1 8.8 65.7 33.6 5.4 9.3 2.4 4.6 24.6 7.9 15.3 8.9 8.7 37.0 125.7 0.2 32.3 11.6 26.5 95.1 10.3 67.8 4.6 0.2 13.4 13.6 49.4 30.4 4.0 0.2 33.3 1.7 103.0 23.6 28.2 40.1 18.6 2.7 20.1 0.4 4.3 54.3 0.3 0.6 11.0 56.3 20.9 8.7 6.7 16.7 85.8 117.5 4.6 4.7 49.5 70.1 9.7 33.7 74.7 4.3 17.6 14.9 39.3 13.7 17.3 0.8 0.3 0.3 15.2 2.3 17.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 10.7 1.8 15.6 12.4 6.5 5.2 5.5 4.3 4.2 7.7 8.8 5.7 12.8 56.9 5.5 0.6 73.9 37.0 52.7 59.2 0.6 69.8 42.3 3.8 72.9 52.0 27.6 2.1 15.6 1.5 154.4 9.8 47.3 4.2 54.7 5.6 8.7 28.9 1.3 10.2 66.7 5.2 6.7 51.0 50.2 27.8 10.2 4.6 10.6 2.9 0.0 5.2 54.0 48.8 0.8 6.5 5.1 8.7 2.2 7.2 3.7 2.4 0.8 0.0 2.0 0.4 60.7 64.6 4.9 0.3 80.9 84.7 14.8 60.7 0.1 6.6 3.1 7.5 3.8 2.7 59.7 83.1 7.9 2.1 59.9 65.4 99.6 KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 Q8N8K9 9 112486827-112669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5" "Cell type enhanced" "Detected in many" "Astrocytes: 169.8;Excitatory neurons: 64.2;Inhibitory neurons: 55.1;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 166.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020625 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA020625: AB_1852451" "unprognostic (3.09e-3)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (1.33e-1)" "unprognostic (7.48e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (4.95e-2)" "unprognostic (1.14e-1)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (7.67e-2)" "unprognostic (5.48e-3)" "unprognostic (3.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.58e-1)" 1.1 6.6 5.5 1.1 10.5 4.9 2.2 9.3 6.9 5.1 4.4 1.4 1.7 3.4 0.9 1.5 3.0 1.3 1.3 3.9 6.6 5.8 3.4 2.1 1.3 8.2 8.9 9.9 2.6 1.4 1.8 0.7 7.0 1.5 1.5 10.0 3.0 2.4 0.9 1.6 1.9 3.1 7.5 1.5 4.8 5.8 10.7 3.9 2.4 0.8 1.3 1.4 1.9 14.5 3.7 5.2 20.7 6.0 1.4 0.3 9.9 2.7 0.9 3.2 3.6 9.5 2.4 11.8 3.1 8.9 2.2 3.2 15.3 1.5 4.5 3.6 6.2 4.6 7.3 6.7 0.8 7.0 5.6 0.6 1.2 4.2 2.0 2.9 2.6 11.0 11.0 2.9 1.0 4.2 11.0 4.0 11.4 8.6 2.4 8.8 11.8 3.3 4.3 5.1 10.6 11.2 4.5 4.7 2.7 11.4 4.3 7.1 0.5 1.1 6.1 0.7 3.3 5.3 10.4 6.9 1.4 4.8 0.8 0.4 0.7 0.0 0.5 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.4 0.6 0.6 0.6 0.2 0.6 0.1 0.4 5.5 10.5 9.3 6.9 3.9 6.6 8.2 8.9 7.0 7.5 10.7 14.5 0.5 3.2 19.3 169.8 3.7 4.7 3.4 1.5 6.8 20.6 7.9 4.2 4.3 4.3 6.2 1.8 14.6 1.2 3.0 4.6 7.9 3.2 4.1 12.1 8.1 1.4 4.8 3.8 64.2 6.7 1.0 3.3 8.2 8.0 0.0 20.3 0.4 8.0 1.0 6.7 55.1 4.4 12.2 7.5 4.6 2.5 6.5 4.2 1.8 15.9 2.5 8.3 3.1 127.6 166.4 3.3 6.2 5.3 5.0 6.5 5.0 11.0 5.9 12.1 6.6 2.5 4.1 1.5 8.0 5.3 4.7 0.8 1.6 29.9 5.2 5.7 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 162.3;pancreas: 85.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 105.8;Collecting duct cells: 90.1;Distal tubular cells: 80.3;Ductal cells: 43.3;Enteroendocrine cells: 64.1;Proximal enterocytes: 60.3;Proximal tubular cells: 79.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;OE19: 17.2;RPTEC TERT1: 44.8;SCLC-21H: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.1 0.0 2.2 1.1 2.1 0.0 25.3 0.4 3.6 11.4 2.8 7.8 25.5 4.2 1.0 0.2 8.0 24.7 0.2 2.0 0.9 162.3 27.7 1.6 0.5 0.6 1.1 0.7 85.4 0.8 0.6 1.1 1.0 7.0 4.2 0.1 3.6 4.8 0.0 1.4 16.1 0.4 0.4 0.2 11.0 2.4 1.3 1.3 31.8 0.0 0.1 0.2 0.3 0.8 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 9.6 0.2 0.0 5.2 0.0 0.6 0.0 0.2 0.1 0.2 0.0 0.9 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.0 0.4 0.1 17.2 0.6 0.0 0.0 0.1 44.8 0.2 6.6 0.1 0.0 0.9 0.0 0.2 4.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 0.4 3.6 2.0 0.9 0.6 1.1 1.0 0.4 1.3 0.8 0.1 0.0 4.4 0.0 1.3 0.0 0.9 0.6 0.0 0.0 20.3 10.8 0.4 105.8 0.0 90.1 0.0 0.1 0.0 7.9 80.3 43.3 7.0 8.3 1.5 0.3 64.1 0.0 0.7 11.8 9.3 0.4 14.8 15.6 0.0 0.0 0.0 10.2 0.3 0.0 0.3 22.0 0.0 0.3 0.0 14.7 0.6 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.7 21.3 0.0 0.0 2.2 60.3 79.1 0.0 0.0 0.0 0.0 0.3 3.2 7.9 0.0 0.0 0.5 0.9 0.3 28.9 0.5 KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 18.9;Early spermatids: 44.0;Hepatic stellate cells: 15.4;Late spermatids: 88.7;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;hTERT-HME1: 3.7;U-2 OS: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" 0.0 0.2 2.3 0.0 2.2 0.0 0.0 0.0 3.3 0.3 1.8 0.2 0.1 0.4 0.0 0.0 1.8 0.0 0.0 2.3 4.9 0.4 0.1 0.2 0.0 0.6 1.4 0.2 0.0 0.0 0.6 0.0 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.3 0.0 0.0 23.2 3.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.8 0.7 0.4 0.0 0.0 0.0 0.1 1.2 1.6 0.6 0.4 0.2 0.4 0.0 0.5 0.9 0.3 0.0 0.6 0.4 0.4 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.3 0.5 3.7 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.2 2.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.2 0.0 3.3 2.3 4.9 0.6 1.4 0.4 0.3 3.1 0.0 18.9 0.0 0.0 0.7 0.2 1.7 0.0 0.1 0.6 0.0 0.2 0.3 2.8 0.0 0.2 1.8 4.2 0.1 2.8 0.1 0.0 0.0 44.0 2.8 0.3 15.2 0.0 0.0 11.0 0.0 0.1 0.9 0.0 0.2 0.0 0.0 15.4 0.5 5.1 0.0 2.8 0.0 0.0 1.6 9.8 88.7 1.2 3.2 1.8 1.9 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.1 0.1 0.1 0.3 3.5 0.3 19.7 0.5 2.7 3.2 4.3 0.1 1.3 1.6 0.2 5.2 0.1 0.2 KIF19 "FLJ37300, KIF19A" ENSG00000196169 "Kinesin family member 19" Q2TAC6 17 74326210-74355820 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 16.7;fallopian tube: 12.0;lymphoid tissue: 13.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 44.4;Enteroendocrine cells: 23.8;Hepatic stellate cells: 15.4;Intestinal goblet cells: 14.1;Plasma cells: 15.6;Respiratory ciliated cells: 57.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.1" "Lineage enriched" "Detected in single" 22 "T-cells: 2.1" "Cell line enriched" "Detected in single" 9 "SCLC-21H: 4.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043638, HPA073303" Enhanced Approved "Plasma membrane,Actin filaments,Centrosome" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "Actin filaments, Centrosome" "HPA043638: AB_10962579, HPA073303: AB_2686593" "unprognostic (1.59e-3)" "unprognostic (1.05e-1)" "unprognostic (1.00e-1)" "unprognostic (5.37e-3)" "unprognostic (9.64e-2)" "unprognostic (1.64e-1)" "unprognostic (2.70e-2)" "unprognostic (2.81e-1)" "unprognostic (1.03e-1)" "unprognostic (9.83e-3)" "unprognostic (1.05e-3)" "unprognostic (1.14e-1)" "unprognostic (1.59e-9)" "unprognostic (5.16e-5)" "unprognostic (2.72e-1)" "unprognostic (1.67e-2)" "unprognostic (1.53e-1)" 1.4 0.1 7.5 0.4 10.3 0.2 1.2 4.0 11.4 2.2 3.5 1.7 3.0 0.3 0.0 0.5 12.0 0.4 0.3 7.2 7.4 0.2 0.9 1.9 0.1 7.5 8.0 0.2 1.1 0.0 0.3 0.0 5.9 0.9 0.6 0.1 1.0 0.2 0.4 0.6 2.3 0.4 6.2 13.5 0.7 0.6 7.7 1.0 1.9 0.6 0.1 1.6 1.5 16.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.3 0.6 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.4 7.5 10.3 4.0 11.4 7.2 7.4 7.5 8.0 5.9 6.2 7.7 16.7 1.3 0.0 0.0 2.0 1.3 0.0 0.4 2.5 0.0 1.1 0.1 0.0 1.6 0.0 6.3 0.0 0.0 0.0 3.5 0.8 0.0 0.0 0.5 44.4 0.2 4.2 23.8 0.4 0.0 0.0 3.1 1.0 1.1 0.7 0.0 0.0 15.4 0.1 0.1 0.0 0.1 14.1 4.1 0.6 1.6 0.3 0.0 0.3 3.6 0.0 0.1 5.7 3.1 4.0 3.7 0.0 0.1 0.0 15.6 0.3 0.2 0.0 57.6 0.3 0.0 1.8 1.3 0.2 1.6 0.0 0.1 0.0 2.5 0.2 1.9 0.2 KIF21A "FEOM1, FLJ20052" ENSG00000139116 "Kinesin family member 21A" Q7Z4S6 12 39293228-39443390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.3;retina: 77.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 308.6;Cone photoreceptor cells: 308.6;Inhibitory neurons: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.1;MAIT T-cell: 3.4;memory CD4 T-cell: 4.4;memory CD8 T-cell: 7.3;naive CD8 T-cell: 4.8;NK-cell: 3.0;T-reg: 2.2" "Group enriched" "Detected in many" 9 "NK-cells: 3.0;T-cells: 7.3" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 187.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022079, HPA058432" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Cytosol "CAB022079: , HPA058432: AB_2683717" "unprognostic (1.08e-3)" "unprognostic (3.40e-1)" "unprognostic (2.06e-2)" "unprognostic (7.67e-2)" "unprognostic (1.13e-1)" "unprognostic (3.09e-1)" "unprognostic (2.24e-3)" "unprognostic (7.77e-2)" "unprognostic (3.17e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.73e-2)" "prognostic favorable (8.07e-8)" "unprognostic (4.05e-2)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (2.34e-2)" 6.5 12.1 37.4 3.9 40.0 0.9 6.2 41.4 51.2 12.3 8.0 11.9 9.0 9.2 5.5 20.9 33.7 6.1 19.2 38.2 55.7 26.5 20.5 5.9 2.9 67.4 46.6 4.5 13.2 16.6 16.0 5.7 70.3 11.2 13.1 77.6 23.9 3.1 15.3 12.7 10.3 8.7 39.3 6.5 12.5 12.5 46.5 2.2 8.8 9.5 5.3 5.9 11.4 44.3 18.5 23.2 31.8 13.7 6.0 3.0 25.4 4.5 2.2 5.9 4.1 42.2 22.4 0.0 14.1 1.9 9.4 16.0 18.5 11.2 5.4 36.1 14.7 0.2 40.6 38.6 4.6 31.0 0.1 2.0 24.4 7.4 35.3 13.4 7.7 7.8 35.4 36.9 4.8 11.1 4.0 0.0 42.8 0.0 20.0 0.1 0.0 21.1 22.3 30.1 43.0 187.6 17.7 27.7 10.8 32.1 32.2 3.9 5.6 3.4 13.7 1.1 13.1 16.7 6.1 0.0 8.1 4.4 2.9 0.0 0.0 0.0 7.1 0.0 3.4 0.5 4.4 7.3 0.0 0.0 1.0 4.8 0.1 3.0 0.0 0.0 2.2 1.0 37.4 40.0 41.4 51.2 38.2 55.7 67.4 46.6 70.3 39.3 46.5 44.3 4.1 38.5 17.5 205.7 5.3 18.5 25.1 25.9 4.6 308.6 10.9 11.0 121.9 22.8 53.9 12.9 308.6 15.3 36.2 30.0 9.8 27.8 108.4 78.1 30.2 5.5 24.0 2.5 189.9 41.3 100.8 17.2 36.2 27.7 13.4 92.7 12.8 44.2 3.8 138.0 221.0 28.7 22.4 2.5 2.2 79.9 3.1 2.4 14.2 23.4 7.8 112.3 25.7 124.1 160.3 37.2 20.0 2.6 30.7 37.5 20.7 53.3 193.9 186.1 0.0 26.1 17.4 57.2 24.0 30.5 30.7 59.1 33.5 17.7 29.3 21.7 KIF21B "DKFZP434J212, KIAA0449" ENSG00000116852 "Kinesin family member 21B" O75037 1 200969390-201023714 "Plasma proteins, Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 34.1;brain: 21.6;retina: 21.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 25.7;Cone photoreceptor cells: 58.4;Late spermatids: 82.1;Rod photoreceptor cells: 26.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 5 "basophil: 6.0" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.0" "Cell line enhanced" "Detected in many" "Daudi: 39.1;HMC-1: 41.0;JURKAT: 78.8;Karpas-707: 49.6;RPMI-8226: 43.8;U-266/70: 90.2;U-266/84: 44.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027249, HPA027274" Approved Approved "Plasma membrane,Mitotic spindle,Cytosol" Yes No "Cluster 11: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Cytosol" "HPA027249: AB_10602241, HPA027274: AB_1852483" "unprognostic (3.49e-2)" "unprognostic (1.82e-1)" "unprognostic (4.70e-2)" "unprognostic (2.15e-1)" "unprognostic (2.28e-1)" "unprognostic (3.92e-3)" "unprognostic (1.32e-2)" "unprognostic (1.80e-1)" "unprognostic (2.18e-1)" "unprognostic (3.03e-1)" "unprognostic (1.54e-3)" "unprognostic (7.14e-2)" "unprognostic (1.41e-4)" "unprognostic (5.98e-3)" "unprognostic (2.64e-1)" "unprognostic (6.81e-2)" "unprognostic (5.81e-4)" 1.6 0.8 16.1 9.4 16.4 34.1 1.3 0.0 16.5 0.9 0.0 2.4 2.0 0.7 0.4 0.8 1.2 2.1 0.7 21.6 8.3 0.9 1.5 4.8 12.9 5.9 5.7 0.7 0.8 6.0 0.6 0.9 6.5 0.8 1.8 21.4 1.4 0.7 0.3 0.7 6.7 0.8 1.5 12.3 2.5 13.7 9.5 11.8 1.0 0.4 8.0 2.3 0.8 7.9 1.3 1.5 11.8 0.5 0.0 0.0 3.0 0.1 0.0 0.3 0.1 0.7 0.4 39.1 0.5 0.0 3.4 0.3 1.2 0.3 0.4 1.9 0.4 9.7 0.2 0.2 1.0 29.4 41.0 1.0 4.1 0.4 0.7 0.0 1.5 78.8 4.6 49.6 0.0 0.2 24.5 11.2 5.2 3.9 0.0 8.4 0.1 43.8 0.2 0.0 7.2 1.0 0.6 0.5 0.6 2.1 0.2 8.9 2.8 0.0 3.3 0.0 0.2 90.2 44.7 19.3 3.9 12.8 0.3 6.0 0.0 0.6 0.8 0.2 0.9 0.4 0.6 0.8 0.1 0.3 0.5 0.6 1.0 1.3 0.3 0.1 0.6 0.4 16.1 16.4 0.0 16.5 21.6 8.3 5.9 5.7 6.5 1.5 9.5 7.9 1.5 0.0 3.8 22.5 11.0 1.0 0.5 0.2 0.0 25.7 0.4 0.8 1.5 0.0 0.1 1.8 58.4 0.0 17.4 1.2 0.0 0.5 20.4 0.1 0.2 1.8 0.0 4.8 15.6 1.6 0.1 0.6 1.1 0.4 6.3 0.5 1.4 0.3 1.7 1.7 11.8 1.4 0.0 4.4 3.1 82.1 0.9 5.3 0.0 8.4 2.7 20.0 13.4 14.6 4.0 2.4 0.3 0.0 12.0 0.4 0.2 0.0 0.1 26.1 6.6 0.6 1.1 1.9 3.7 0.1 1.0 0.0 18.0 0.1 1.1 2.0 KIF26A "DKFZP434N178, KIAA1236" ENSG00000066735 "Kinesin family member 26A" Q9ULI4 14 104138723-104180894 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 22.4;Endothelial cells: 11.9;Enteroendocrine cells: 7.7;Hepatic stellate cells: 13.9;Horizontal cells: 18.5;Spermatogonia: 8.1" "Group enriched" "Detected in many" 5 "stomach cancer: 3.8;testis cancer: 14.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 30.6;MCF7: 24.9;NTERA-2: 20.8;REH: 18.8;SCLC-21H: 19.2;SH-SY5Y: 39.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046882, HPA060346" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046882: AB_2679856, HPA060346: AB_2684259" "unprognostic (3.01e-1)" "unprognostic (3.20e-1)" "unprognostic (3.95e-1)" "unprognostic (1.77e-2)" "unprognostic (2.79e-1)" "unprognostic (1.12e-1)" "unprognostic (5.49e-3)" "unprognostic (1.69e-1)" "unprognostic (1.21e-2)" "unprognostic (3.31e-3)" "unprognostic (5.24e-3)" "unprognostic (7.01e-2)" "prognostic unfavorable (7.78e-4)" "unprognostic (7.96e-2)" "unprognostic (1.72e-1)" "unprognostic (9.12e-2)" "unprognostic (4.68e-3)" 5.0 2.3 2.1 0.7 1.3 2.0 4.6 0.5 1.5 5.0 3.0 2.6 0.4 2.4 0.2 1.4 2.6 0.4 5.7 0.8 1.4 3.8 0.6 2.2 0.3 1.3 1.3 4.1 5.7 0.3 2.9 1.8 1.4 0.8 0.4 0.1 1.0 0.8 2.9 2.8 1.9 0.4 0.9 4.2 1.8 2.8 1.8 0.2 1.5 1.0 0.1 2.0 2.1 0.5 0.0 1.7 1.0 3.9 0.0 0.0 6.7 0.3 0.0 0.0 0.0 3.1 0.0 0.0 5.3 0.0 0.7 2.5 3.1 0.0 0.0 0.0 4.9 0.0 30.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.6 6.7 0.0 0.0 0.0 24.9 0.0 0.0 20.8 0.2 2.0 18.8 7.9 2.0 0.0 0.0 19.2 39.3 4.4 0.6 0.0 2.5 0.4 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 1.3 0.5 1.5 0.8 1.4 1.3 1.3 1.4 0.9 1.8 0.5 22.4 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 0.3 0.1 3.2 0.0 0.0 1.8 0.0 1.0 0.0 1.3 1.9 0.7 0.4 0.2 4.4 11.9 7.7 4.8 0.5 0.2 0.8 2.1 0.0 0.2 0.0 0.4 13.9 0.2 2.6 18.5 0.7 2.6 0.0 0.3 1.1 0.1 0.0 0.1 1.8 3.7 0.0 0.2 0.0 0.0 0.1 0.2 1.0 0.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.7 0.7 0.2 8.1 1.2 1.7 0.4 0.1 0.3 2.8 0.0 KIF26B FLJ10157 ENSG00000162849 "Kinesin family member 26B" Q2KJY2 1 245154985-245709432 "Predicted intracellular proteins" "Developmental protein, Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.2" "Group enriched" "Detected in many" 4 "Inhibitory neurons: 282.0;Oligodendrocyte precursor cells: 378.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cell line enhanced" "Detected in some" "HSkMC: 16.5;REH: 15.2;SH-SY5Y: 14.4;U-937: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027709, HPA028478, HPA028561, HPA028562" Enhanced Approved "Plasma membrane,Microtubules" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Microtubules" "HPA027709: AB_10600215, HPA028478: AB_10601231, HPA028561: AB_10601960, HPA028562: AB_10602417" "unprognostic (3.66e-1)" "unprognostic (5.67e-2)" "unprognostic (7.90e-3)" "unprognostic (4.50e-3)" "unprognostic (3.23e-2)" "unprognostic (1.49e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.30e-3)" "unprognostic (3.63e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-2)" "unprognostic (5.77e-2)" "unprognostic (1.17e-4)" "unprognostic (7.22e-3)" 0.1 0.7 2.4 0.3 2.1 0.0 0.4 4.1 3.3 1.1 0.0 0.7 0.1 0.7 0.2 0.2 0.4 0.8 0.5 2.1 3.7 1.0 0.2 1.1 0.2 2.8 6.2 0.1 0.2 0.4 0.4 1.7 3.1 0.8 0.0 0.1 0.4 0.8 0.0 1.2 0.3 0.5 3.2 0.3 0.5 0.5 2.6 0.3 1.0 0.0 0.2 0.4 0.2 1.8 0.0 0.0 2.2 3.9 1.1 1.3 1.5 1.9 2.4 0.1 0.0 2.2 0.0 0.0 3.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.1 0.3 16.5 0.7 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 15.2 0.2 0.0 2.0 0.0 4.0 14.4 0.0 0.0 0.0 2.8 0.0 0.9 0.2 3.3 0.0 0.0 1.1 0.0 0.0 0.0 0.7 7.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.4 2.1 4.1 3.3 2.1 3.7 2.8 6.2 3.1 3.2 2.6 1.8 0.1 0.0 0.5 9.8 0.0 0.9 0.1 0.8 0.6 1.0 0.8 1.7 2.3 0.0 1.1 7.3 4.2 2.4 2.8 0.0 0.0 2.0 2.1 4.3 17.7 0.6 0.0 0.0 34.6 4.8 2.8 2.1 1.5 1.1 0.0 1.4 0.0 0.0 0.8 0.0 282.0 0.0 0.0 0.0 0.4 5.6 0.6 0.6 3.6 66.5 0.8 0.5 0.0 378.0 9.8 9.2 0.0 0.0 0.0 0.2 0.2 0.5 2.0 0.4 0.0 0.8 1.5 1.1 2.0 0.5 1.3 2.5 0.3 0.1 0.5 0.0 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.5" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 41.9" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 15.7;RPMI-8226: 37.4;SCLC-21H: 7.4;SH-SY5Y: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.0 0.0 2.9 0.1 1.8 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 3.8 0.3 0.1 0.1 0.1 4.0 2.2 0.0 1.3 0.3 1.1 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.4 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.3 4.1 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.7 0.0 0.0 0.3 0.1 0.0 0.6 1.2 0.4 1.0 0.0 37.4 0.0 0.0 7.4 20.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 1.8 0.9 3.4 1.3 3.8 4.0 2.2 3.9 1.0 8.5 0.8 0.1 0.0 0.0 0.0 1.0 0.1 0.1 0.5 0.0 1.1 1.2 1.4 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 41.9 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.8 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.0 4.2 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.0 0.3 0.3 0.3 1.6 0.9 0.2 0.1 0.2 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLC1 "hKLC1B, hKLC1G, hKLC1J, hKLC1N, hKLC1P, hKLC1R, hKLC1S, KLC, KNS2, KNS2A" ENSG00000126214 "Kinesin light chain 1" Q07866 14 103561896-103714249 "Predicted intracellular proteins" "Host-virus interaction" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 397.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009798, HPA044617, HPA052450" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 14000 "Cluster 26: Non-specific - Mitochondria" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB009798: AB_2280879, HPA044617: AB_2679024, HPA052450: AB_2681838" "unprognostic (6.93e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (7.94e-2)" "unprognostic (2.60e-1)" "unprognostic (1.19e-1)" "unprognostic (1.21e-3)" "unprognostic (2.67e-2)" "unprognostic (9.21e-2)" "unprognostic (5.62e-2)" "prognostic favorable (6.75e-4)" "unprognostic (6.84e-3)" "prognostic unfavorable (7.17e-4)" "unprognostic (6.58e-2)" "unprognostic (8.69e-2)" "unprognostic (4.05e-1)" "unprognostic (1.49e-1)" 70.8 49.4 282.9 42.2 302.0 50.3 63.0 273.5 358.7 74.8 220.4 89.9 26.2 71.5 43.9 66.0 65.0 38.4 100.0 310.6 299.8 35.6 29.9 66.0 44.2 378.9 305.0 62.8 43.0 48.5 86.7 45.9 397.0 47.1 34.3 158.6 54.2 47.1 123.4 68.2 48.7 58.0 300.0 49.0 53.9 45.6 301.7 40.2 48.6 71.5 47.4 66.5 69.8 304.0 57.0 74.2 138.6 76.3 92.6 102.8 65.5 129.5 105.4 118.6 81.7 64.0 60.8 75.8 65.2 139.3 53.2 93.0 85.8 69.6 112.0 89.9 43.9 41.6 92.8 66.1 106.8 83.4 79.5 73.4 109.3 89.6 112.1 126.5 104.2 52.8 63.5 83.7 104.4 94.6 56.9 74.0 45.6 90.1 140.4 53.0 60.6 38.2 74.7 122.5 165.1 93.5 105.7 52.7 90.2 85.9 47.9 40.1 152.7 88.4 43.5 123.1 74.1 65.9 50.0 83.3 101.7 47.7 97.0 5.5 4.6 9.8 7.3 4.6 6.6 5.0 6.5 7.8 5.1 6.8 5.7 5.0 5.0 3.1 6.5 7.6 7.0 2.9 282.9 302.0 273.5 358.7 310.6 299.8 378.9 305.0 397.0 300.0 301.7 304.0 45.2 44.8 32.6 92.4 24.3 26.0 45.1 30.1 13.6 140.8 18.7 19.7 39.3 15.7 21.5 20.2 52.1 22.6 29.5 17.9 9.8 42.9 8.0 30.8 41.8 45.5 44.9 13.2 84.1 30.7 30.6 37.4 27.0 43.2 33.6 31.5 39.3 18.9 30.5 138.0 80.8 24.3 28.5 19.9 23.8 17.0 38.5 24.4 39.2 73.1 36.3 45.4 20.6 57.3 89.8 71.2 17.3 48.2 26.2 46.6 15.8 5.1 23.8 106.1 26.3 46.4 46.8 64.8 83.3 20.1 17.6 42.1 30.8 17.1 17.5 38.4 KLC2 FLJ12387 ENSG00000174996 "Kinesin light chain 2" Q9H0B6 11 66257294-66267860 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Horizontal cells: 55.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040416, HPA040434" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "Nucleoplasm, Mitochondria" "HPA040416: AB_10795524, HPA040434: AB_10795367" "unprognostic (1.29e-1)" "unprognostic (4.95e-3)" "unprognostic (2.99e-1)" "unprognostic (3.24e-2)" "unprognostic (2.33e-1)" "prognostic unfavorable (3.16e-4)" "unprognostic (2.43e-3)" "unprognostic (2.45e-2)" "unprognostic (6.27e-3)" "unprognostic (1.60e-1)" "unprognostic (3.49e-2)" "unprognostic (1.64e-3)" "unprognostic (4.57e-3)" "unprognostic (1.96e-2)" "unprognostic (1.81e-1)" "unprognostic (1.72e-2)" "unprognostic (8.08e-2)" 15.2 18.0 18.8 9.5 25.4 3.6 15.9 33.0 78.1 27.3 0.0 28.5 9.8 27.1 6.3 18.2 21.6 8.9 32.1 26.6 12.7 22.4 8.2 18.9 9.1 39.8 10.8 24.6 15.5 15.2 48.3 7.2 37.0 28.7 4.7 28.4 15.9 16.0 57.8 18.3 16.3 11.2 5.7 13.7 20.2 32.2 23.1 25.1 17.7 14.2 6.4 27.2 21.7 35.8 49.4 58.2 28.3 16.9 16.9 13.5 21.9 34.1 24.2 34.2 26.1 31.9 14.3 21.3 31.9 25.6 43.9 40.7 29.3 33.2 11.4 35.7 37.2 4.4 48.0 22.4 32.1 9.9 22.7 13.5 42.7 40.1 32.8 22.0 16.1 26.2 24.1 29.0 27.8 69.2 56.8 15.0 27.8 14.2 49.2 21.4 14.6 30.1 27.2 27.4 76.3 37.5 24.6 22.1 41.3 15.7 36.3 6.7 26.8 55.5 49.8 68.2 45.5 30.7 27.4 11.9 39.3 6.7 22.9 0.0 0.2 0.5 2.4 0.1 3.1 1.9 1.1 1.6 0.3 3.2 1.1 1.4 0.3 1.3 0.2 2.1 0.3 1.1 18.8 25.4 33.0 78.1 26.6 12.7 39.8 10.8 37.0 5.7 23.1 35.8 4.0 3.2 1.5 8.8 8.9 8.9 9.2 11.1 7.4 34.4 10.1 7.2 2.4 7.2 5.5 12.9 12.5 9.9 5.1 3.1 13.7 14.8 10.1 7.7 6.2 5.2 37.1 0.8 20.7 8.2 18.2 6.5 13.7 9.7 0.0 8.6 3.9 2.3 3.1 55.5 19.0 7.2 18.3 3.2 4.0 4.6 8.7 2.8 12.4 5.6 6.3 14.6 4.1 4.0 6.2 19.1 4.9 13.9 9.1 18.2 3.9 10.3 7.3 35.2 0.0 9.5 13.3 26.2 29.8 8.9 9.7 12.7 8.2 3.4 4.9 8.5 KLF9 BTEB1 ENSG00000119138 "Kruppel like factor 9" Q13886 9 70384597-70414624 "Predicted intracellular proteins, Transcription factors" "Biological rhythms, Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 264.3;Skeletal myocytes: 223.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 60.4;ASC TERT1: 83.0;HHSteC: 107.4;HSkMC: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029308 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane, Cytosol" "HPA029308: AB_10601923" "unprognostic (2.12e-2)" "unprognostic (2.56e-1)" "unprognostic (3.12e-1)" "unprognostic (2.69e-2)" "unprognostic (5.86e-2)" "unprognostic (1.37e-1)" "unprognostic (3.64e-3)" "unprognostic (4.34e-1)" "unprognostic (5.55e-1)" "unprognostic (9.47e-2)" "unprognostic (7.86e-2)" "unprognostic (3.44e-1)" "prognostic favorable (6.59e-6)" "unprognostic (1.43e-3)" "unprognostic (1.75e-1)" "unprognostic (3.17e-2)" "unprognostic (1.02e-2)" 82.0 36.5 12.5 22.8 22.1 18.2 67.6 29.8 22.5 29.9 14.9 66.5 15.3 56.5 16.7 41.1 73.0 42.6 54.7 15.7 14.4 54.9 91.3 71.6 14.4 21.3 21.1 63.4 52.9 51.1 25.5 10.2 17.3 36.5 26.2 19.2 35.4 24.4 123.3 40.8 33.2 58.9 15.6 22.9 48.9 7.7 21.7 12.1 57.1 94.7 14.3 43.4 37.2 19.1 0.4 0.6 0.0 7.8 60.4 83.0 0.8 4.1 27.1 1.4 3.0 0.1 3.6 0.1 3.0 7.5 2.0 0.1 11.9 18.4 2.8 0.0 9.3 4.2 13.1 2.4 107.4 2.1 10.9 71.6 18.4 1.1 25.9 37.1 23.9 1.8 8.4 16.4 10.2 1.3 0.3 6.2 0.7 1.2 3.9 0.0 3.7 10.9 5.0 0.0 1.0 5.2 37.3 21.5 45.2 2.5 7.1 6.7 32.8 7.1 5.1 8.2 2.2 11.8 13.5 0.6 6.4 6.6 35.9 0.7 0.1 0.1 0.4 0.1 0.6 0.9 0.5 0.4 0.3 0.6 0.7 0.4 0.0 0.1 0.2 0.4 0.6 0.1 12.5 22.1 29.8 22.5 15.7 14.4 21.3 21.1 17.3 15.6 21.7 19.1 264.3 41.7 25.5 25.8 36.5 48.2 62.7 13.0 97.3 45.3 48.3 34.7 74.1 64.3 22.3 14.7 20.9 0.2 51.0 36.7 31.3 10.5 22.3 40.6 171.6 124.3 13.8 14.5 32.1 13.1 0.5 180.8 55.5 59.6 7.6 2.0 109.9 158.8 3.7 80.8 13.7 32.3 14.2 70.1 44.6 18.1 90.7 81.3 39.2 29.0 9.7 126.1 19.6 3.0 11.1 12.8 26.1 85.0 30.2 74.0 54.5 39.7 17.4 10.1 78.9 223.8 203.5 2.1 3.2 72.7 34.2 0.0 54.9 16.3 31.9 33.3 KLHDC7B MGC16635 ENSG00000130487 "Kelch domain containing 7B" Q96G42 22 50545899-50551023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.2;parathyroid gland: 13.7" "Cell type enhanced" "Detected in some" "B-cells: 5.2;Collecting duct cells: 5.5;granulocytes: 5.7;Kupffer cells: 5.2;monocytes: 21.1;NK-cells: 10.3;T-cells: 5.7" "Group enriched" "Detected in many" 4 "cervical cancer: 42.3;head and neck cancer: 11.4;urothelial cancer: 40.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HMC-1: 97.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000518, HPA076540" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA000518: AB_1079213, HPA076540: " "prognostic favorable (1.30e-4)" "unprognostic (3.18e-2)" "unprognostic (2.74e-2)" "unprognostic (2.21e-1)" "unprognostic (3.96e-2)" "unprognostic (6.04e-3)" "unprognostic (3.91e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (7.13e-2)" "unprognostic (3.33e-3)" "unprognostic (2.48e-1)" "unprognostic (2.09e-3)" "unprognostic (2.89e-1)" "unprognostic (4.69e-2)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" 0.2 0.2 0.2 2.1 0.1 1.0 0.3 0.1 0.2 0.5 0.1 0.3 0.4 0.2 0.3 0.4 0.1 0.3 0.0 0.1 0.2 3.7 0.4 0.7 2.3 0.5 0.2 0.0 0.1 13.7 1.0 0.1 0.3 0.4 0.1 0.0 1.3 0.2 0.0 0.3 1.1 0.1 0.2 2.7 0.5 0.2 0.4 5.2 2.0 0.0 1.3 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.8 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.2 97.7 0.1 1.2 0.0 0.2 0.1 0.0 0.0 0.0 11.6 0.0 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.3 0.0 0.1 1.1 1.1 0.1 2.0 1.9 1.4 1.9 2.1 2.6 0.9 1.3 2.3 2.0 0.2 0.7 1.4 0.3 2.0 1.5 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.2 0.3 0.2 0.4 0.2 0.0 0.0 0.6 0.0 5.2 0.1 0.0 1.6 0.0 0.0 3.0 1.4 0.5 0.0 1.6 5.5 0.0 0.0 2.5 0.1 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.7 0.1 0.2 0.5 0.3 5.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 5.2 1.2 0.0 0.0 2.7 0.0 0.0 21.1 0.0 10.3 0.0 0.0 1.3 0.0 0.0 2.8 0.1 0.0 0.3 1.6 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 KLHL41 "KBTBD10, Krp1, SARCOSIN" ENSG00000239474 "Kelch like family member 41" O60662 2 169509702-169526258 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant, Nemaline myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 42 "skeletal muscle: 5038.6;tongue: 3473.7" "Group enriched" "Detected in some" 21 "Cardiomyocytes: 108.1;Skeletal myocytes: 251.8" "Group enriched" "Detected in some" 9 "head and neck cancer: 10.8;prostate cancer: 3.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HSkMC: 21.6;LHCN-M2: 35.4;RH-30: 55.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA021165, HPA021753, HPA021760" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Nucleoplasm, Plasma membrane" "HPA021165: AB_1852087, HPA021753: AB_1852089, HPA021760: AB_1852091" "unprognostic (2.44e-2)" "unprognostic (6.12e-2)" "unprognostic (9.01e-2)" "unprognostic (2.94e-2)" "unprognostic (2.90e-1)" "unprognostic (1.36e-3)" "unprognostic (2.05e-1)" "unprognostic (5.46e-3)" "unprognostic (1.88e-1)" "unprognostic (5.38e-2)" "unprognostic (6.65e-4)" "unprognostic (9.64e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-3)" "unprognostic (1.19e-1)" "unprognostic (1.12e-2)" "unprognostic (1.52e-1)" 1.5 0.5 1.7 0.2 1.4 0.0 2.0 3.1 1.8 1.0 1.4 1.4 0.1 0.8 1.5 75.1 1.2 6.7 100.3 1.2 1.6 0.8 0.9 2.7 0.3 0.9 2.5 1.1 1.1 0.5 5.8 0.1 1.5 50.0 0.3 16.1 52.1 0.7 5038.6 4.6 0.8 0.6 0.9 0.8 1.3 2.6 5.1 1.7 2.2 3473.7 0.3 5.9 0.9 1.4 0.0 0.1 0.0 0.6 0.4 2.7 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 4.3 0.1 0.0 0.0 0.2 0.2 0.0 21.6 0.5 0.3 0.0 0.2 0.1 0.2 0.1 0.0 35.4 0.1 0.1 0.2 0.0 0.0 0.2 0.0 55.9 0.0 0.2 0.1 0.7 0.1 0.1 0.0 1.5 0.1 0.0 0.1 0.0 0.4 0.2 0.4 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.4 3.1 1.8 1.2 1.6 0.9 2.5 1.5 0.9 5.1 1.4 0.0 0.0 0.5 1.3 0.0 0.1 0.5 0.1 0.0 2.4 0.2 0.1 108.1 0.0 2.0 0.0 8.4 0.0 0.0 0.1 0.0 0.5 5.8 1.3 0.2 1.0 1.2 0.0 4.1 0.5 0.0 6.4 0.0 0.1 0.0 0.2 0.4 0.2 0.2 0.0 4.6 0.1 0.0 0.3 0.0 2.9 0.9 0.8 0.0 3.7 0.0 0.7 0.0 1.5 2.3 0.7 0.1 1.2 0.0 0.3 0.0 0.3 4.1 5.8 0.0 251.8 1.8 4.1 0.4 0.0 0.0 0.0 0.3 0.2 0.0 0.1 KLHL6 FLJ00029 ENSG00000172578 "Kelch like family member 6" Q8WZ60 3 183487551-183555706 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 31.0" "Cell type enhanced" "Detected in many" "B-cells: 35.7;Endometrial ciliated cells: 28.3;granulocytes: 51.1;Hofbauer cells: 24.1;Macrophages: 33.3;Plasma cells: 63.6;Respiratory ciliated cells: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 41.3;HEL: 26.6;HMC-1: 26.7;U-266/70: 82.1;U-266/84: 45.5;U-698: 121.3" "Low region specificity" "Detected in all" HPA024512 Uncertain Approved "Plasma membrane,Microtubules,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 2: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Centriolar satellite" "Plasma membrane, Microtubules, Mitotic spindle" "HPA024512: AB_2131015" "unprognostic (8.46e-2)" "unprognostic (3.67e-4)" "unprognostic (1.48e-2)" "unprognostic (6.03e-4)" "unprognostic (5.15e-2)" "unprognostic (1.30e-3)" "unprognostic (1.39e-1)" "unprognostic (5.05e-2)" "unprognostic (7.43e-2)" "unprognostic (9.62e-2)" "unprognostic (8.24e-2)" "unprognostic (2.68e-1)" "prognostic unfavorable (3.53e-4)" "unprognostic (1.81e-1)" "unprognostic (3.68e-2)" "unprognostic (2.42e-1)" "unprognostic (5.73e-2)" 1.5 0.7 0.7 11.8 0.8 3.5 0.9 1.0 1.0 0.8 0.7 2.5 2.5 0.6 0.2 0.6 4.8 2.1 0.7 0.6 1.4 0.4 1.0 4.2 29.3 2.6 1.4 0.3 0.6 0.2 0.2 1.9 2.0 0.5 2.3 0.1 1.3 0.1 0.2 0.1 4.8 0.7 1.5 6.3 4.1 0.2 3.1 10.0 0.6 0.3 31.0 1.8 0.3 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 21.9 0.0 26.6 0.0 0.0 0.0 7.3 26.7 0.0 0.0 0.0 0.0 0.0 4.6 0.5 0.4 18.4 0.0 0.0 8.8 4.1 0.0 0.0 0.0 14.8 0.1 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 2.5 0.0 0.1 0.0 0.1 82.1 45.5 121.3 0.0 8.0 0.0 7.8 2.8 11.8 0.6 2.2 0.7 3.6 2.4 1.0 2.0 2.4 2.9 1.8 2.4 2.2 2.7 4.6 4.2 2.6 0.7 0.8 1.0 1.0 0.6 1.4 2.6 1.4 2.0 1.5 3.1 3.7 4.0 6.4 6.5 0.7 35.7 1.1 1.7 0.6 0.6 0.6 0.3 0.4 4.8 0.0 5.4 0.0 2.1 0.2 16.6 0.2 0.0 0.1 2.0 28.3 0.5 4.6 0.0 7.6 0.3 0.0 0.3 1.7 2.0 0.8 51.1 8.1 1.1 0.2 24.1 0.0 0.3 0.0 0.0 20.7 22.4 0.8 0.3 33.3 8.8 14.0 10.1 0.3 5.2 1.0 0.3 0.0 0.1 0.0 63.6 1.2 0.0 0.4 24.4 0.7 0.0 1.8 1.5 0.3 0.4 0.1 0.6 0.5 16.8 0.0 0.2 1.2 KLHL7 "KLHL6, RP42, SBBI26" ENSG00000122550 "Kelch like family member 7" Q8IXQ5 7 23105758-23177914 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ubl conjugation pathway" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 50.8" "Cell type enhanced" "Detected in all" "Early spermatids: 560.6;Late spermatids: 242.7;Oligodendrocyte precursor cells: 168.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029491, HPA029492" Uncertain Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029491: AB_10599605, HPA029492: AB_10600881" "unprognostic (1.24e-2)" "unprognostic (4.45e-1)" "unprognostic (1.77e-1)" "unprognostic (4.55e-2)" "unprognostic (1.29e-2)" "unprognostic (1.65e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (3.78e-1)" "unprognostic (6.10e-2)" "unprognostic (6.41e-3)" "unprognostic (1.30e-1)" "unprognostic (1.51e-1)" "prognostic favorable (8.98e-5)" "unprognostic (2.46e-2)" "unprognostic (3.55e-3)" "unprognostic (3.23e-2)" "unprognostic (2.27e-2)" 9.5 18.8 12.8 7.0 13.3 12.4 13.0 16.3 15.9 10.5 12.1 9.2 7.8 11.5 12.2 9.0 9.7 9.7 50.8 12.5 13.1 11.9 10.4 7.7 8.3 12.6 12.7 11.8 7.7 10.8 7.3 8.6 12.3 10.1 7.9 14.9 8.5 8.1 9.1 10.9 6.9 10.5 12.2 8.0 6.3 42.2 13.4 12.4 9.2 9.7 9.1 8.7 9.4 14.7 24.7 20.7 55.7 66.3 26.8 23.2 20.3 21.3 31.5 30.7 35.6 25.3 17.5 24.1 16.8 26.2 50.5 26.2 21.5 15.0 25.8 6.4 15.5 15.9 16.7 32.9 20.0 32.5 12.0 20.7 19.1 35.2 28.8 24.2 39.6 29.4 28.3 25.5 50.7 28.4 27.3 51.3 77.0 16.7 24.5 23.7 31.2 22.2 29.2 21.0 33.5 32.5 46.2 22.7 23.3 33.9 18.9 16.9 17.0 25.7 26.6 56.9 25.7 39.9 35.3 58.6 17.0 33.8 31.5 44.1 15.3 67.2 13.0 17.9 13.7 9.2 13.8 12.3 11.1 11.9 10.1 10.0 14.4 9.5 15.8 8.0 16.7 12.6 12.8 13.3 16.3 15.9 12.5 13.1 12.6 12.7 12.3 12.2 13.4 14.7 12.1 22.4 5.5 45.7 13.0 23.6 18.2 13.0 18.2 23.7 12.3 13.5 101.2 8.6 11.3 9.2 29.2 20.7 14.4 5.7 11.7 17.7 560.6 18.3 16.7 15.8 10.8 25.6 74.5 17.6 27.1 19.8 10.2 13.2 21.5 16.3 13.2 7.0 19.7 37.0 75.2 7.6 14.2 16.0 17.2 242.7 16.8 12.6 12.4 35.6 13.4 30.3 8.2 168.9 45.6 19.4 1.9 20.7 12.3 11.5 7.4 13.5 18.8 16.3 6.6 14.3 17.9 83.7 19.7 24.6 33.8 23.7 17.2 12.1 7.0 24.0 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 8 "dendritic cells: 104.2;NK-cells: 254.3;T-cells: 100.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Cell line enhanced" "Detected in some" "HeLa: 5.6;Karpas-707: 1.9" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" 0.7 0.5 0.8 2.2 0.8 5.3 2.0 0.6 1.4 0.7 0.4 1.8 1.4 3.1 1.5 1.4 0.9 2.0 0.7 1.0 1.6 0.3 1.8 3.3 3.1 1.4 1.4 0.7 0.8 0.3 0.3 2.2 1.0 0.7 2.0 1.2 1.2 0.4 0.4 1.0 2.6 0.9 1.2 6.7 4.3 0.9 1.8 1.1 0.7 0.0 2.5 1.0 0.6 2.0 0.2 0.8 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.8 0.0 0.6 0.1 0.0 0.2 1.6 0.1 0.3 1.4 0.5 0.4 0.2 1.0 5.6 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.3 0.6 1.9 0.4 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.1 1.7 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.4 0.0 1.9 0.3 0.2 229.2 0.3 29.1 0.6 0.1 40.1 0.3 0.2 0.3 33.2 6.4 367.6 0.6 0.4 0.1 28.6 0.8 0.8 0.6 1.4 1.0 1.6 1.4 1.4 1.0 1.2 1.8 2.0 1.2 0.0 0.6 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.9 1.3 0.5 1.5 0.0 0.0 0.0 0.1 104.2 0.8 0.0 0.1 1.3 0.3 0.4 0.4 1.8 11.2 0.2 0.0 0.0 0.6 3.1 0.4 0.0 0.0 3.9 0.9 0.1 1.7 0.1 2.8 0.0 4.0 0.4 0.4 0.6 2.0 5.4 0.0 1.4 0.0 254.3 1.0 0.0 0.0 1.2 1.2 17.6 0.1 0.6 0.6 0.0 2.0 0.0 0.1 0.8 1.1 0.6 0.5 0.1 0.1 100.2 0.0 0.5 0.4 KLRC2 "CD159c, NKG2-C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;lymphoid tissue: 5.8" "Group enriched" "Detected in some" 6 "dendritic cells: 111.5;Oligodendrocyte precursor cells: 32.6;T-cells: 49.9" "Cancer enriched" "Detected in single" 8 "glioma: 3.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "gdT-cell: 24.6;NK-cell: 84.5" "Group enriched" "Detected in many" 103 "NK-cells: 84.5;T-cells: 24.6" "Cell line enhanced" "Detected in some" "GAMG: 19.1;HEL: 5.8;HeLa: 17.5;HSkMC: 4.1" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (9.05e-4)" "unprognostic (2.54e-2)" "unprognostic (3.77e-2)" "unprognostic (2.51e-3)" "unprognostic (2.83e-1)" "unprognostic (9.49e-4)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (2.88e-1)" "unprognostic (4.00e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-9)" "unprognostic (8.10e-2)" "unprognostic (2.34e-1)" "unprognostic (8.93e-2)" "unprognostic (5.31e-3)" 0.4 0.1 3.9 0.4 3.8 2.2 0.8 3.6 9.4 0.3 2.8 1.3 0.7 0.9 0.0 0.5 0.5 1.1 0.1 3.7 4.1 0.1 0.8 1.0 1.1 4.2 4.2 1.0 0.2 0.0 0.1 0.4 4.1 0.3 0.8 0.3 0.3 0.2 0.0 0.1 1.1 0.0 4.2 5.8 2.3 0.4 3.9 0.3 0.3 0.0 1.3 0.4 0.3 4.7 0.0 0.9 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 19.1 0.0 0.0 2.2 0.0 0.0 0.0 5.8 17.5 0.3 0.0 0.6 0.0 4.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.1 1.2 0.1 0.4 0.0 0.0 0.0 0.0 0.6 2.8 0.1 0.1 0.0 0.0 0.0 24.6 0.0 0.6 0.0 0.0 11.0 0.0 0.0 0.1 9.2 0.5 84.5 0.1 0.0 0.0 4.6 3.9 3.8 3.6 9.4 3.7 4.1 4.2 4.2 4.1 4.2 3.9 4.7 0.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.3 1.2 0.0 0.6 0.0 0.0 0.0 111.5 0.2 0.0 0.2 0.0 0.1 0.1 0.1 9.6 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.2 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 9.2 32.6 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 49.9 1.7 0.3 0.2 KLRF1 "CLEC5C, NKp80" ENSG00000150045 "Killer cell lectin like receptor F1" Q9NZS2 12 9827481-9845007 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.8;lymphoid tissue: 18.0" "Group enriched" "Detected in many" 7 "dendritic cells: 302.0;NK-cells: 963.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "NK-cell: 664.4" "Lineage enriched" "Detected in all" 7 "NK-cells: 664.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.5;HAP1: 1.5;U-937: 4.4" HPA054038 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA054038: " "unprognostic (2.96e-1)" "unprognostic (8.59e-2)" "unprognostic (3.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-4)" "unprognostic (6.06e-2)" "unprognostic (3.68e-2)" "unprognostic (9.95e-3)" "unprognostic (3.00e-1)" "unprognostic (2.90e-1)" "unprognostic (4.43e-2)" "unprognostic (6.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.89e-3)" 1.5 0.1 0.6 1.4 0.6 12.8 0.8 0.6 1.4 0.7 0.6 0.7 0.3 0.9 3.8 0.6 1.5 1.4 0.6 0.6 0.6 1.2 4.5 4.4 3.4 0.8 0.6 0.1 1.3 0.3 0.5 1.0 0.6 0.5 1.0 0.1 1.4 1.1 1.2 0.5 0.8 0.8 0.6 18.0 1.2 0.6 0.6 0.4 0.8 0.4 3.5 0.9 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.4 0.6 0.4 0.8 0.9 71.5 1.5 94.4 3.4 3.6 35.2 1.5 1.5 1.4 35.4 5.8 664.4 1.1 2.3 1.2 83.0 0.6 0.6 0.6 1.4 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 3.2 0.0 2.2 0.0 2.3 1.5 1.1 0.2 0.6 0.0 1.3 0.1 0.3 5.7 1.3 0.0 0.0 0.9 302.0 0.1 9.8 0.5 0.5 0.5 0.5 2.2 0.0 24.0 0.1 0.2 0.7 1.2 0.0 1.0 1.3 0.1 8.9 1.8 1.4 0.0 0.2 0.1 0.0 9.1 6.6 1.1 0.0 2.1 12.4 2.8 3.9 0.4 963.0 0.0 0.3 0.4 0.0 0.0 12.7 0.9 0.0 0.8 0.2 0.0 0.0 0.1 0.2 0.2 2.0 0.2 1.1 0.5 80.6 0.0 0.3 3.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 KMT2D "ALR, CAGL114, MLL2, MLL4, TNRC21" ENSG00000167548 "Lysine methyltransferase 2D" O14686 12 49018978-49060794 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Methyltransferase, Transferase" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.5" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035977 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA035977: AB_10670673" "unprognostic (8.33e-2)" "unprognostic (1.49e-1)" "unprognostic (9.14e-2)" "unprognostic (2.52e-1)" "unprognostic (8.07e-2)" "unprognostic (6.91e-3)" "unprognostic (7.35e-2)" "unprognostic (2.29e-1)" "unprognostic (3.57e-1)" "unprognostic (5.14e-2)" "unprognostic (7.23e-2)" "unprognostic (3.07e-1)" "unprognostic (1.68e-2)" "unprognostic (7.10e-2)" "unprognostic (1.87e-1)" "unprognostic (3.20e-2)" "unprognostic (7.60e-2)" 19.9 21.9 14.0 17.0 14.4 62.1 20.3 14.7 18.1 20.2 3.8 21.3 13.2 26.9 14.4 25.5 24.1 11.7 23.7 12.1 9.1 18.2 20.5 25.1 17.5 9.3 8.2 25.3 33.2 22.9 25.4 16.2 8.6 19.2 14.7 48.0 22.1 16.2 44.9 30.4 27.9 15.5 3.1 36.6 25.5 23.6 12.7 29.0 26.5 21.9 17.2 19.4 19.4 13.4 32.3 31.9 31.0 24.7 29.3 20.4 32.6 17.3 17.1 20.3 10.9 54.8 14.1 33.4 21.2 23.9 14.0 21.5 38.1 19.9 17.7 22.4 26.7 47.2 37.7 29.9 20.5 59.1 43.2 18.4 25.8 30.7 32.0 27.3 31.8 33.2 55.1 19.2 23.7 37.4 26.8 48.0 29.9 45.4 25.0 37.4 22.4 12.0 18.1 37.2 24.6 21.2 28.1 25.5 19.5 26.1 24.0 44.1 49.8 15.5 30.7 14.5 30.5 24.8 20.9 31.7 17.1 28.0 12.5 0.5 0.2 0.3 0.2 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.1 0.1 1.5 0.5 0.0 0.2 0.0 0.1 14.0 14.4 14.7 18.1 12.1 9.1 9.3 8.2 8.6 3.1 12.7 13.4 12.9 9.6 19.1 17.6 13.3 14.0 7.8 8.1 14.2 26.8 12.1 7.1 7.8 12.8 10.9 18.4 52.1 8.2 15.3 12.3 1.9 6.3 2.8 10.7 12.7 13.2 13.1 16.0 17.4 6.0 6.0 8.8 24.5 13.1 8.2 23.3 17.9 13.0 9.8 21.9 16.5 10.0 6.1 15.7 18.4 2.4 9.6 15.4 10.6 15.0 14.9 6.4 17.5 12.5 19.8 8.8 9.5 10.9 10.1 11.0 13.3 4.5 9.0 38.4 6.6 14.4 12.5 6.5 3.8 18.9 17.6 11.4 15.3 10.8 10.3 9.6 KNDC1 "bB439H18.3, C10orf23, FLJ25027, KIAA1768, RASGEF2, v-KIND, Very-KIND" ENSG00000171798 "Kinase non-catalytic C-lobe domain containing 1" Q76NI1 10 133160219-133226412 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 44.0;pituitary gland: 27.5" "Cell type enhanced" "Detected in many" "Astrocytes: 93.4;Excitatory neurons: 41.9;Inhibitory neurons: 36.3;Respiratory ciliated cells: 25.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;EFO-21: 1.2;MCF7: 1.1;NTERA-2: 1.4;RPMI-8226: 2.1;SuSa: 1.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039624, HPA056143" Uncertain Approved "Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 38: EFO-21 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" Vesicles "HPA039624: AB_10671045, HPA056143: " "unprognostic (2.32e-1)" "unprognostic (1.11e-1)" "unprognostic (6.35e-4)" "unprognostic (1.59e-3)" "unprognostic (1.96e-2)" "unprognostic (2.76e-1)" "unprognostic (5.61e-2)" "unprognostic (2.75e-2)" "unprognostic (6.77e-2)" "unprognostic (1.15e-1)" "unprognostic (6.80e-3)" "unprognostic (2.46e-3)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.53e-1)" "unprognostic (1.94e-1)" "unprognostic (9.41e-2)" 1.5 13.7 31.1 0.1 17.9 0.0 0.2 8.4 44.0 2.3 0.0 0.3 0.0 2.8 0.7 0.2 9.0 0.2 0.3 19.8 9.1 0.8 6.5 2.8 0.0 17.3 13.3 8.5 0.5 0.4 27.5 0.4 10.3 1.1 0.0 0.9 0.6 0.9 0.0 0.2 0.2 0.4 3.0 0.5 0.3 1.8 22.7 0.0 2.5 0.0 0.0 0.2 0.9 13.1 0.2 0.3 0.2 1.6 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.6 0.2 0.0 1.2 0.1 0.5 0.2 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 1.4 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 31.1 17.9 8.4 44.0 19.8 9.1 17.3 13.3 10.3 3.0 22.7 13.1 0.0 0.0 9.0 93.4 0.2 0.0 0.1 0.4 0.0 1.6 0.2 0.0 2.4 1.5 4.2 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 14.2 1.5 0.2 3.0 0.0 41.9 0.0 0.1 1.4 0.0 0.3 0.0 1.5 0.4 4.6 0.2 1.7 36.3 0.0 0.0 1.0 0.4 1.0 3.7 1.2 0.0 5.6 0.3 4.5 0.0 6.6 2.1 0.0 0.0 1.2 0.0 0.1 0.0 0.0 25.9 1.0 0.0 0.1 0.5 0.0 1.7 0.0 0.3 0.1 0.4 1.2 0.0 0.0 KNSTRN "C15orf23, FLJ14502, kinastrin, SKAP, TRAF4AF1" ENSG00000128944 "Kinetochore localized astrin (SPAG5) binding protein" Q9Y448 15 40382721-40394246 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 63.6;thyroid gland: 53.1" "Cell type enhanced" "Detected in many" "Early spermatids: 328.2;Late spermatids: 600.1;Spermatocytes: 145.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042027 Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Mitotic spindle, Centriolar satellite" "Plasma membrane" "HPA042027: AB_10797378" "unprognostic (2.35e-3)" "unprognostic (6.83e-2)" "unprognostic (3.01e-1)" "unprognostic (5.23e-3)" "unprognostic (6.19e-2)" "unprognostic (2.28e-2)" "unprognostic (1.54e-3)" "unprognostic (2.47e-3)" "unprognostic (1.23e-1)" "unprognostic (2.55e-1)" "prognostic unfavorable (3.43e-5)" "unprognostic (6.31e-2)" "prognostic unfavorable (7.88e-9)" "unprognostic (1.70e-1)" "unprognostic (1.58e-1)" "unprognostic (2.67e-1)" "unprognostic (1.52e-2)" 8.0 6.2 6.3 8.1 7.1 14.1 14.3 7.7 8.6 5.1 4.5 7.9 9.2 6.4 12.3 9.1 5.7 4.4 7.4 7.2 6.2 7.2 12.0 5.8 14.5 6.2 6.2 5.1 5.0 8.4 5.6 10.7 6.5 6.8 10.4 9.0 10.3 7.2 12.2 6.7 6.2 10.2 5.9 7.1 10.2 63.6 6.1 25.6 53.1 12.4 16.1 5.6 5.6 7.7 103.4 47.5 92.7 61.0 20.1 30.9 48.1 69.9 54.0 141.0 123.3 102.6 44.2 39.7 34.8 47.3 112.1 115.7 100.0 64.8 126.5 70.8 48.8 117.7 107.4 65.2 18.9 63.8 58.6 16.1 36.5 71.3 70.6 34.5 80.3 97.6 86.3 66.8 120.0 52.2 55.6 51.2 58.6 87.7 71.2 56.4 69.7 45.7 49.7 42.3 89.9 62.5 58.3 63.3 15.1 55.8 66.5 45.3 41.6 67.5 68.8 69.7 98.3 56.5 98.6 70.5 41.8 84.0 56.5 13.2 17.6 17.4 7.9 24.3 6.8 9.5 5.7 7.0 18.4 11.2 5.4 5.5 9.7 9.8 47.8 12.7 9.4 7.1 6.3 7.1 7.7 8.6 7.2 6.2 6.2 6.2 6.5 5.9 6.1 7.7 2.4 9.6 1.1 2.6 4.1 2.2 2.9 7.6 3.4 8.2 4.2 3.4 7.3 1.5 5.4 0.0 8.4 25.2 2.5 1.9 3.9 8.5 328.2 5.9 4.9 3.7 2.4 34.3 5.1 9.3 40.8 5.2 5.6 4.4 1.3 16.9 3.6 8.0 21.6 5.0 4.9 5.3 14.2 9.8 2.0 600.1 9.0 8.2 3.6 4.7 8.0 8.5 6.2 2.0 4.3 12.3 0.5 7.2 12.6 4.9 2.8 5.8 7.2 8.5 0.0 3.7 6.5 145.7 19.2 7.0 1.4 21.1 5.1 8.5 6.4 3.0 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KPTN 2E4 ENSG00000118162 "Kaptin, actin binding protein" Q9Y664 19 47475150-47484265 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "plasmacytoid DC: 23.9" "Lineage enriched" "Detected in all" 4 "dendritic cells: 23.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041710, HPA041796" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "Nucleoplasm, Vesicles" "HPA041710: AB_10961904, HPA041796: AB_10962832" "unprognostic (4.80e-3)" "unprognostic (2.22e-1)" "unprognostic (7.24e-2)" "unprognostic (1.53e-1)" "unprognostic (5.54e-2)" "unprognostic (3.47e-2)" "prognostic unfavorable (7.91e-6)" "unprognostic (9.30e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-2)" "unprognostic (5.51e-2)" "unprognostic (2.59e-2)" "prognostic unfavorable (7.82e-4)" "unprognostic (1.40e-1)" "unprognostic (8.72e-2)" "unprognostic (2.04e-1)" "unprognostic (2.34e-1)" 5.2 6.6 5.1 3.0 5.5 5.6 4.7 5.9 8.4 7.2 3.6 6.2 3.4 5.3 1.4 7.7 4.4 2.4 5.8 5.6 5.1 6.3 8.6 4.5 3.4 5.6 5.1 3.2 5.5 4.0 10.0 2.8 5.0 8.0 2.2 1.6 10.1 2.0 6.9 4.8 4.5 2.6 4.6 6.1 4.7 5.4 5.1 8.2 4.8 6.7 2.1 5.1 5.8 5.4 9.7 16.8 12.9 8.6 12.9 10.0 9.3 5.4 9.9 28.4 17.5 12.6 11.3 12.3 4.1 9.5 10.1 11.1 11.0 19.1 7.9 11.4 17.2 5.2 12.2 11.4 11.5 10.1 13.8 11.5 12.3 9.5 8.7 7.2 11.0 15.2 10.1 10.9 8.3 7.8 17.7 44.8 11.6 10.5 10.3 12.6 6.3 4.8 8.8 15.0 27.8 21.1 9.1 10.3 6.8 6.4 8.5 14.5 6.6 6.9 7.6 3.7 12.2 2.8 4.8 5.3 6.1 6.4 10.4 0.0 3.9 1.7 1.4 3.4 0.4 1.5 1.0 1.2 4.6 1.6 1.3 1.1 3.2 1.2 5.3 23.9 1.7 2.2 5.1 5.5 5.9 8.4 5.6 5.1 5.6 5.1 5.0 4.6 5.1 5.4 2.6 3.2 2.7 4.6 4.8 2.8 8.5 13.8 2.8 5.8 5.8 3.9 3.7 4.3 8.9 5.5 6.2 14.5 12.1 3.4 9.8 9.6 0.8 3.1 3.3 3.0 3.0 0.8 4.7 4.2 13.3 5.0 5.1 3.4 2.5 4.9 3.3 6.2 8.5 10.1 3.5 2.5 8.2 5.6 2.8 2.5 1.2 5.8 1.8 1.9 2.5 6.9 5.2 3.0 4.3 5.0 1.8 0.7 6.5 4.4 4.3 8.3 2.9 4.0 0.0 3.5 3.5 4.9 18.9 4.5 3.1 15.3 1.7 8.2 4.0 5.8 KRT75 K6HF ENSG00000170454 "Keratin 75" O95678 12 52424070-52434371 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 27.5" "Cell type enriched" "Detected in some" 7 "Ductal cells: 20.4" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 36.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "PC-3: 38.5;U-2 OS: 50.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019367, HPA076201" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1500000000 "Cluster 61: Skin - Cornification" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Cytosol "Plasma membrane" "HPA019367: AB_1852239, HPA076201: AB_2686786" "unprognostic (2.83e-2)" "unprognostic (2.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (8.85e-3)" "unprognostic (2.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (6.60e-2)" "unprognostic (9.20e-2)" "unprognostic (5.19e-2)" "unprognostic (2.45e-1)" "unprognostic (8.98e-2)" "unprognostic (1.94e-1)" 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 50.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.6 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 20.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "HaCaT: 3.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" 0.6 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 273.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.2 0.0 0.0 0.0 0.0 0.0 KRTAP25-1 KAP25.1 ENSG00000232263 "Keratin associated protein 25-1" Q3LHN0 21 30289145-30289514 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA031438 Uncertain Approved "Nuclear membrane,Plasma membrane,Cytosol" NA NA "Nuclear membrane" "Plasma membrane, Cytosol" "HPA031438: AB_10610000" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LAMTOR1 "C11orf59, FLJ20625, p18, p27RF-Rho, Pdro, Ragulator1" ENSG00000149357 "Late endosomal/lysosomal adaptor, MAPK and MTOR activator 1" Q6IAA8 11 72085895-72103297 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002997 Approved Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 160000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA002997: AB_1845531" "unprognostic (7.32e-2)" "unprognostic (1.79e-1)" "unprognostic (3.94e-2)" "unprognostic (3.77e-2)" "unprognostic (2.30e-1)" "unprognostic (2.71e-2)" "prognostic unfavorable (3.63e-4)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (1.94e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-3)" "unprognostic (1.78e-3)" "unprognostic (3.08e-1)" "unprognostic (2.46e-1)" "unprognostic (1.00e-1)" "unprognostic (1.04e-1)" 100.7 143.8 171.2 69.1 177.8 118.6 96.2 173.2 180.4 87.0 162.1 88.6 67.5 86.5 90.0 114.1 74.9 65.8 131.9 163.5 169.5 129.5 114.2 91.3 80.6 177.4 177.2 81.5 85.6 87.0 92.0 67.4 174.9 102.4 76.5 46.6 85.8 71.7 126.4 89.9 82.5 73.7 175.4 130.9 96.6 41.2 176.1 75.4 112.3 109.3 79.4 88.5 77.9 172.5 94.2 181.0 97.3 132.0 224.7 152.3 97.6 129.0 201.6 206.2 151.7 230.9 139.7 93.1 162.3 216.9 214.2 138.1 171.1 260.1 155.8 117.8 99.3 245.6 108.5 156.5 291.4 97.2 147.7 252.3 199.2 224.4 224.0 116.4 173.1 102.5 104.1 96.0 211.4 295.6 86.2 146.1 93.9 291.8 194.9 73.7 178.9 78.8 246.8 195.1 65.7 103.3 127.6 127.5 343.7 106.4 192.6 93.2 125.3 137.5 98.0 323.8 93.0 111.6 139.0 80.4 81.8 81.8 113.0 113.4 414.3 274.1 80.6 228.8 77.7 132.1 75.6 81.1 332.6 146.2 63.4 77.9 229.5 122.8 180.6 197.1 98.8 397.5 171.2 177.8 173.2 180.4 163.5 169.5 177.4 177.2 174.9 175.4 176.1 172.5 132.6 44.8 71.6 9.1 109.7 55.7 161.7 271.1 117.8 58.5 159.9 195.7 66.4 121.5 120.2 128.8 12.5 266.5 110.7 235.4 295.4 276.4 12.4 61.2 98.9 134.9 116.4 133.5 9.8 340.2 300.1 111.6 71.4 85.2 97.7 71.5 142.1 86.9 468.0 77.4 12.9 140.2 170.9 248.5 111.6 19.2 107.8 311.5 113.8 8.4 413.6 223.7 177.1 10.1 24.2 307.3 202.6 102.7 87.9 193.4 230.3 370.9 61.0 56.1 111.7 102.5 116.3 58.7 103.3 126.1 55.4 282.0 89.4 178.5 170.8 157.2 LAPTM4A "HUMORF13, KIAA0108, LAPTM4, MBNT, Mtrp" ENSG00000068697 "Lysosomal protein transmembrane 4 alpha" Q15012 2 20032650-20051628 "Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 1393.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031402, HPA031404, HPA068554" Approved Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Golgi apparatus, Vesicles" "Plasma membrane" "HPA031402: AB_10669882, HPA031404: AB_10670293, HPA068554: AB_2686003" "unprognostic (2.01e-1)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (5.73e-1)" "unprognostic (6.04e-2)" "unprognostic (3.00e-2)" "unprognostic (1.53e-3)" "unprognostic (5.37e-2)" "unprognostic (1.27e-1)" "unprognostic (3.65e-2)" "prognostic unfavorable (4.37e-4)" "unprognostic (8.70e-2)" "unprognostic (1.05e-2)" "unprognostic (7.78e-3)" "unprognostic (2.18e-2)" "unprognostic (7.98e-3)" "unprognostic (2.36e-1)" 360.5 451.0 116.8 177.1 114.9 199.5 338.5 120.7 146.8 469.8 150.8 256.2 219.6 507.6 339.7 315.4 370.1 383.7 322.5 112.7 130.2 460.9 409.2 308.0 160.1 123.3 122.2 460.3 290.8 289.2 155.6 397.6 128.1 306.3 233.9 59.1 306.0 611.8 204.4 247.2 227.7 412.2 130.1 190.9 240.5 389.3 125.5 122.8 365.8 234.8 178.5 342.1 248.7 128.0 417.7 228.8 136.4 283.2 1393.4 1031.8 509.1 514.3 651.8 349.3 393.6 180.5 398.4 73.2 116.2 637.9 356.9 400.7 115.0 250.6 317.8 181.2 183.2 112.4 244.3 520.1 534.8 86.7 294.9 691.7 501.2 338.7 386.4 481.9 367.6 62.2 86.6 135.8 527.5 243.3 53.8 114.0 299.2 353.1 207.1 89.3 397.5 139.7 858.6 347.7 214.8 207.3 480.4 390.5 335.9 492.9 169.6 70.1 467.5 575.7 203.8 500.3 336.5 221.7 349.2 118.3 455.3 172.8 234.4 737.8 382.3 289.3 94.6 324.9 116.4 197.4 112.9 106.9 269.2 192.3 126.7 113.7 200.1 124.3 393.4 226.9 119.3 427.0 116.8 114.9 120.7 146.8 112.7 130.2 123.3 122.2 128.1 130.1 125.5 128.0 351.7 195.5 203.1 39.2 156.5 659.0 601.1 1210.5 339.2 24.4 330.3 306.1 211.7 380.3 727.7 553.6 12.5 224.4 109.8 174.8 162.4 539.4 1235.7 195.7 407.1 384.0 138.1 65.0 15.0 347.6 1035.3 896.8 111.6 286.0 521.9 445.7 331.3 519.4 311.3 20.2 14.3 203.6 767.0 299.3 716.0 1080.9 835.3 254.4 588.7 39.4 278.0 315.3 48.4 34.7 18.7 289.4 246.2 600.7 156.8 331.2 171.5 940.9 506.7 24.7 532.5 389.4 583.0 356.3 173.5 268.2 709.8 302.9 146.4 579.1 224.8 500.9 LASP1 "Lasp-1, MLN50" ENSG00000002834 "LIM and SH3 protein 1" Q14847 17 38869859-38921770 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Ion transport, Transport" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 591.7;Proximal enterocytes: 292.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012072, CAB022049" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 9400000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Focal adhesion sites" "CAB022049: , HPA012072: AB_1852714" "unprognostic (1.23e-1)" "unprognostic (2.09e-2)" "unprognostic (1.77e-1)" "prognostic unfavorable (4.57e-4)" "unprognostic (1.47e-1)" "unprognostic (3.03e-2)" "prognostic unfavorable (2.41e-4)" "unprognostic (1.06e-3)" "unprognostic (2.24e-1)" "unprognostic (9.60e-2)" "unprognostic (9.87e-3)" "unprognostic (1.01e-1)" "unprognostic (9.65e-3)" "unprognostic (1.29e-3)" "unprognostic (3.95e-2)" "unprognostic (1.60e-3)" "unprognostic (4.53e-2)" 86.4 38.0 60.8 75.9 56.7 126.4 55.5 45.5 56.7 46.9 48.6 93.0 131.9 43.8 32.3 45.9 46.0 56.8 40.3 56.1 61.0 55.9 76.4 68.6 76.1 56.2 63.5 48.5 59.0 25.5 33.0 81.4 59.0 30.9 92.3 26.8 44.8 33.9 23.7 44.4 168.8 51.2 52.9 74.3 96.2 23.9 67.4 74.1 34.9 27.7 78.2 53.2 37.3 50.1 214.1 441.0 124.1 111.0 182.8 196.9 218.7 267.8 257.8 274.5 198.5 134.3 225.8 98.8 214.1 417.3 154.9 332.4 58.5 204.1 239.6 71.6 31.6 47.5 124.2 235.8 173.0 110.4 134.1 176.3 69.6 234.6 66.1 170.7 188.0 59.0 81.9 30.3 389.4 72.0 127.1 163.6 63.0 189.9 109.4 70.7 67.6 123.8 332.7 187.9 19.0 45.4 159.3 160.5 134.7 233.5 255.7 128.2 331.4 160.0 233.0 189.7 162.0 79.7 115.8 75.2 170.2 96.7 197.2 21.8 31.4 35.0 30.7 33.1 20.3 11.7 15.2 20.4 27.3 10.8 12.7 19.8 67.0 34.2 42.1 20.5 21.4 32.5 60.8 56.7 45.5 56.7 56.1 61.0 56.2 63.5 59.0 52.9 67.4 50.1 54.5 41.7 27.6 17.6 41.8 41.8 21.5 26.0 51.8 66.4 82.4 43.2 1.1 55.8 30.4 73.5 10.4 7.5 69.5 225.2 17.6 65.7 89.6 27.5 31.7 54.3 86.5 21.0 16.4 76.5 59.1 50.1 119.3 46.4 52.0 37.4 64.6 115.4 83.9 26.9 16.0 101.9 28.5 127.7 73.0 591.7 51.9 71.9 35.6 24.4 94.3 22.2 164.8 11.1 4.4 111.0 116.4 39.9 32.8 24.2 292.7 72.9 57.3 23.1 65.7 65.4 53.4 2.9 5.7 62.2 28.4 6.4 63.4 19.2 97.8 31.8 LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.9" "Group enriched" "Detected in many" 6 "dendritic cells: 80.7;granulocytes: 78.9;Macrophages: 55.9;NK-cells: 152.4;T-cells: 151.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 19 "basophil: 307.7;gdT-cell: 303.4;MAIT T-cell: 212.5;memory CD4 T-cell: 295.1;memory CD8 T-cell: 307.2;naive CD4 T-cell: 276.0;naive CD8 T-cell: 266.9;NK-cell: 114.6;T-reg: 410.8" "Group enriched" "Detected in all" 142 "granulocytes: 307.7;NK-cells: 114.6;T-cells: 410.8" "Cell line enhanced" "Detected in many" "HEL: 189.8;HMC-1: 765.9;MOLT-4: 279.5" "Not detected" "Not detected" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 140000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" 8.1 4.4 9.1 23.9 9.6 17.5 6.6 9.0 11.9 15.6 8.1 31.3 9.2 19.3 5.2 8.1 11.6 9.6 3.9 9.2 8.5 15.3 10.5 14.1 65.9 9.2 8.5 7.7 5.7 2.0 14.2 3.9 9.0 21.6 5.2 3.5 7.8 9.5 4.2 10.7 22.7 5.7 8.0 32.0 13.4 4.1 9.7 117.9 17.6 1.6 29.0 24.7 13.3 8.9 1.0 2.3 1.5 2.5 3.7 2.4 4.9 5.5 1.4 1.7 2.2 2.3 3.0 0.7 7.2 2.2 0.6 2.9 2.6 1.3 0.8 1.6 3.3 189.8 5.4 3.3 1.0 5.9 765.9 2.1 3.8 1.7 0.7 2.8 0.9 62.7 2.6 21.7 0.8 5.6 279.5 38.3 3.4 0.4 2.7 3.2 0.8 24.9 1.9 1.6 5.3 1.0 0.9 1.8 2.7 1.4 2.7 31.7 3.6 3.6 18.0 3.9 1.3 7.6 7.0 3.1 45.5 2.7 2.9 307.7 1.4 0.7 303.4 1.5 212.5 1.7 295.1 307.2 1.1 1.7 276.0 266.9 14.6 114.6 1.3 1.9 410.8 196.5 9.1 9.6 9.0 11.9 9.2 8.5 9.2 8.5 9.0 8.0 9.7 8.9 5.2 0.0 13.1 4.6 6.2 7.1 2.1 1.1 2.8 11.0 3.7 4.3 1.7 7.2 3.1 9.2 6.2 2.6 80.7 1.2 1.9 1.7 0.3 1.5 2.3 4.7 0.0 16.6 4.7 0.5 0.9 3.0 7.7 2.7 78.9 4.9 8.6 2.9 14.3 6.7 5.5 1.5 0.0 7.3 9.4 0.1 1.5 55.9 10.6 5.6 9.2 3.0 152.4 3.0 3.5 1.0 0.7 0.7 17.0 2.2 1.3 1.3 1.3 9.6 0.0 3.0 3.8 1.7 2.1 1.9 5.3 2.7 151.7 1.7 1.4 1.3 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LAX1 "FLJ20340, LAX" ENSG00000122188 "Lymphocyte transmembrane adaptor 1" Q8IWV1 1 203765177-203776372 "Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 21.2" "Cell type enhanced" "Detected in some" "dendritic cells: 23.2;granulocytes: 82.2;NK-cells: 30.9;Plasma cells: 65.1;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 14 "B-cells: 7.5;NK-cells: 5.2;T-cells: 12.0" "Group enriched" "Detected in some" 4 "Karpas-707: 22.8;U-266/70: 28.2;U-266/84: 71.9;U-698: 24.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002461, HPA003887, CAB025358" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB025358: , HPA002461: AB_1079239, HPA003887: AB_1079240" "unprognostic (2.85e-3)" "unprognostic (3.83e-3)" "unprognostic (3.90e-4)" "unprognostic (3.65e-2)" "unprognostic (5.22e-2)" "unprognostic (1.03e-5)" "unprognostic (2.99e-2)" "unprognostic (4.91e-2)" "unprognostic (4.36e-2)" "unprognostic (3.31e-3)" "unprognostic (4.77e-1)" "unprognostic (4.36e-1)" "unprognostic (4.23e-4)" "unprognostic (3.07e-1)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (1.51e-1)" 0.5 0.6 0.2 8.8 0.3 1.6 1.7 0.4 0.4 1.4 0.3 3.7 3.1 0.3 0.3 0.9 0.4 2.6 0.3 0.3 0.2 0.2 0.9 2.7 11.8 0.5 0.2 0.2 0.4 0.1 0.0 0.1 0.5 0.7 3.4 0.1 1.2 0.4 0.1 0.2 2.0 0.7 0.2 7.2 4.5 0.3 0.3 11.1 0.2 0.3 21.2 5.1 0.2 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.2 8.0 0.2 22.8 0.0 0.0 8.7 0.0 0.1 0.0 0.0 2.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 28.2 71.9 24.9 0.0 1.9 0.0 0.3 0.0 0.5 12.0 0.0 9.1 7.5 7.1 9.4 0.0 2.5 5.5 7.1 0.3 5.2 0.0 0.0 8.1 3.5 0.2 0.3 0.4 0.4 0.3 0.2 0.5 0.2 0.5 0.2 0.3 0.7 0.9 0.0 1.9 0.0 14.6 1.1 0.4 0.0 0.0 0.0 0.3 0.1 2.6 0.0 0.6 0.0 0.0 0.1 23.2 0.1 0.0 0.2 0.0 0.4 0.4 0.5 0.0 0.0 0.1 0.0 0.0 0.6 1.5 0.4 82.2 0.0 2.2 0.1 0.3 0.0 0.1 0.1 0.0 0.0 1.2 0.0 0.0 1.9 10.6 0.0 0.4 0.0 30.9 0.5 0.0 0.1 0.0 0.0 65.1 0.4 0.6 0.1 0.0 0.0 0.0 0.3 0.9 0.1 0.0 0.2 0.4 0.0 29.2 0.1 0.3 0.5 LCP1 "CP64, L-PLASTIN, LC64P, PLS2" ENSG00000136167 "Lymphocyte cytosolic protein 1" P13796 13 46125920-46211871 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 709.0;epididymis: 402.7;lymphoid tissue: 605.1" "Cell type enhanced" "Detected in many" "dendritic cells: 438.4;granulocytes: 309.1;Hofbauer cells: 264.4;Kupffer cells: 401.2;Langerhans cells: 337.6;Late spermatids: 290.9;Macrophages: 466.1;monocytes: 535.7;NK-cells: 471.7;T-cells: 375.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 875.8;HDLM-2: 799.3;HL-60: 850.7;HMC-1: 861.7;JURKAT: 792.7;NB-4: 789.2;THP-1: 840.5;U-698: 1105.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019493, CAB020673" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA 1800000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "Actin filaments" "CAB020673: , HPA019493: AB_1855457" "unprognostic (2.79e-2)" "unprognostic (8.20e-3)" "unprognostic (1.19e-2)" "unprognostic (3.95e-3)" "unprognostic (1.19e-1)" "unprognostic (2.84e-2)" "unprognostic (2.70e-1)" "unprognostic (4.99e-2)" "unprognostic (6.70e-3)" "unprognostic (2.54e-1)" "unprognostic (5.47e-2)" "unprognostic (3.63e-1)" "unprognostic (3.32e-3)" "unprognostic (2.51e-1)" "unprognostic (1.02e-1)" "unprognostic (7.50e-2)" "unprognostic (2.92e-1)" 85.9 31.1 11.3 396.9 13.1 709.0 43.9 13.9 30.9 28.5 16.8 54.7 42.4 27.4 402.7 29.5 21.5 76.4 14.5 11.3 14.2 13.1 89.0 173.8 563.5 19.7 18.9 10.0 12.2 12.6 4.3 67.2 21.3 184.5 71.2 4.9 44.4 24.3 7.1 40.6 62.3 60.4 18.6 375.2 53.2 33.2 24.8 499.8 23.6 17.8 605.1 133.0 7.7 29.9 36.1 0.2 1.9 0.0 0.0 0.0 409.8 0.1 1.2 3.9 2.9 237.4 1.4 875.8 179.5 0.0 249.1 1.7 0.1 0.6 3.9 799.3 202.9 187.6 0.4 1.1 0.9 850.7 861.7 2.3 0.1 1.4 1.2 0.3 0.0 792.7 100.4 569.7 0.0 2.8 624.8 789.2 1.0 0.4 8.2 451.6 1.6 638.2 0.0 233.8 2.8 7.5 1.9 91.8 6.4 25.0 6.4 840.5 3.1 22.0 13.6 1.5 25.5 135.3 292.5 1105.7 17.0 530.9 3.6 1007.3 1559.5 810.8 915.7 1806.2 822.0 342.3 539.6 761.2 1134.5 251.6 330.2 560.5 1908.6 650.6 1826.1 297.5 598.1 3644.2 11.3 13.1 13.9 30.9 11.3 14.2 19.7 18.9 21.3 18.6 24.8 29.9 7.4 32.1 73.2 0.3 185.2 12.0 1.2 0.0 1.8 0.4 10.3 11.7 4.2 5.7 18.0 3.7 0.0 9.8 438.4 0.2 0.0 16.9 113.1 4.7 42.8 9.6 1.2 63.9 0.5 16.3 68.3 10.9 19.9 7.0 309.1 0.7 12.5 24.0 264.4 0.0 0.5 0.5 0.0 401.2 337.6 290.9 1.2 466.1 23.2 17.8 535.7 23.7 471.7 0.5 1.5 6.8 2.4 1.9 102.4 42.0 0.1 1.5 13.8 1.2 0.0 3.1 6.2 2.7 1.6 2.2 11.8 13.5 375.3 0.5 0.4 4.0 LCTL "FLJ33279, KLG, KLPH" ENSG00000188501 "Lactase like" Q6UWM7 15 66547179-66565979 "Cancer-related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Early spermatids: 5.8;Late spermatids: 9.0" "Group enriched" "Detected in some" 5 "glioma: 1.5;melanoma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.6;hTERT-RPE1: 6.7;NTERA-2: 5.2;SuSa: 6.0;U-2 OS: 14.3;U-251 MG: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071640 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Endoplasmic reticulum" "HPA071640: AB_2686428" "unprognostic (4.60e-2)" "unprognostic (5.46e-2)" "unprognostic (8.70e-2)" "unprognostic (1.56e-2)" "unprognostic (3.22e-3)" "unprognostic (3.53e-2)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (4.51e-3)" "unprognostic (4.44e-16)" "unprognostic (6.06e-2)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" 0.1 0.1 1.4 0.2 1.5 0.4 0.1 1.2 1.5 0.1 1.0 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.3 1.3 0.1 0.1 0.0 0.2 2.1 1.4 0.1 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.3 0.1 0.0 0.7 0.5 0.1 0.0 1.5 0.1 0.1 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.1 3.0 0.3 0.2 2.8 0.2 0.1 0.1 0.7 0.7 0.0 0.0 0.3 0.3 0.4 0.4 5.6 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.1 0.7 0.9 1.4 0.0 0.2 0.3 0.3 0.0 0.3 0.0 6.7 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.4 5.2 0.4 0.1 0.2 3.1 0.3 0.0 0.3 0.3 0.2 0.1 0.3 1.6 6.0 0.4 0.5 0.2 1.4 14.3 0.5 6.4 0.1 0.2 0.2 1.9 0.6 2.7 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.0 1.4 1.5 1.2 1.5 1.3 1.3 2.1 1.4 1.8 1.5 1.6 3.0 0.0 0.0 0.0 2.9 0.7 0.4 0.6 0.0 0.0 0.6 0.1 0.1 0.3 1.5 0.1 0.0 0.0 0.1 0.6 0.2 0.0 0.1 5.8 0.2 0.3 0.2 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.3 9.0 0.6 0.1 0.0 0.0 0.0 1.4 2.1 0.5 1.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.4 0.0 0.6 0.4 1.6 2.1 0.0 0.3 0.3 0.9 0.3 0.1 0.4 LDB2 "CLIM1, LDB1" ENSG00000169744 "LIM domain binding 2" O43679 4 16501541-16898678 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 236.5;Endothelial cells: 194.4;Excitatory neurons: 1314.4;Hepatic stellate cells: 364.8;Inhibitory neurons: 196.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 13 "NK-cell: 2.0" "Lineage enriched" "Detected in single" 13 "NK-cells: 2.0" "Cell line enhanced" "Detected in many" "AF22: 18.3;fHDF/TERT166: 19.0;HAP1: 34.4;HUVEC TERT2: 65.3;TIME: 17.1;U-138 MG: 25.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017544, HPA068634" Supported Supported "Nucleoplasm,Nucleoli,Plasma membrane" No NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Nucleoli" "Plasma membrane" "CAB017544: AB_2137013, HPA068634: AB_2686012" "unprognostic (3.43e-1)" "unprognostic (2.77e-1)" "unprognostic (9.10e-2)" "unprognostic (4.37e-1)" "unprognostic (7.25e-2)" "unprognostic (4.62e-3)" "unprognostic (2.10e-3)" "unprognostic (1.57e-1)" "unprognostic (2.94e-2)" "unprognostic (2.82e-1)" "unprognostic (2.67e-2)" "unprognostic (1.96e-2)" "unprognostic (2.05e-3)" "unprognostic (1.26e-3)" "unprognostic (1.60e-1)" "unprognostic (9.63e-2)" "unprognostic (7.10e-3)" 58.9 15.5 13.7 8.0 19.8 0.4 52.2 3.3 45.9 43.5 7.6 12.7 6.5 65.5 23.4 15.8 28.0 31.2 33.7 23.3 7.3 28.0 26.0 58.2 11.5 4.4 10.9 18.2 7.6 17.0 9.0 58.8 4.7 18.0 8.5 5.3 10.8 13.7 14.0 9.4 12.8 53.8 7.1 50.4 11.5 5.0 7.9 8.3 31.3 24.3 4.8 22.5 22.8 19.7 0.0 0.0 18.3 0.1 10.5 16.9 0.0 10.2 8.0 1.2 2.7 0.0 0.0 0.0 0.0 19.0 0.0 0.0 34.4 0.0 7.3 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 9.5 0.0 12.5 0.0 2.7 65.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 2.7 0.0 0.1 8.8 0.0 0.0 0.8 0.0 0.0 2.3 0.0 0.0 0.0 4.9 0.0 0.0 17.1 25.7 0.1 1.2 0.0 8.3 0.1 0.0 0.2 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.0 0.0 0.0 0.0 0.2 13.7 19.8 3.3 45.9 23.3 7.3 4.4 10.9 4.7 7.1 7.9 19.7 236.5 0.0 5.5 44.7 1.5 8.7 0.3 0.0 2.8 27.1 1.7 2.2 8.7 2.8 0.0 0.0 0.0 0.2 6.8 0.0 0.0 4.4 1.3 1.4 36.5 194.4 0.0 8.0 1314.4 0.2 0.2 44.4 4.1 1.1 5.7 0.1 364.8 3.1 0.4 0.0 196.5 0.0 0.0 16.4 13.2 2.6 38.2 1.4 8.8 117.1 0.0 10.4 3.1 120.6 36.7 0.2 0.0 50.4 0.0 0.3 0.0 0.1 0.7 2.1 6.6 2.8 19.3 0.2 0.7 1.3 6.8 0.1 4.9 39.7 0.0 0.5 LDLRAD3 LRAD3 ENSG00000179241 "Low density lipoprotein receptor class A domain containing 3" Q86YD5 11 35943981-36232136 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 92.4;Excitatory neurons: 68.6;Microglial cells: 104.9;Oligodendrocyte precursor cells: 308.6;Oligodendrocytes: 215.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 4.8;non-classical monocyte: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "hTCEpi: 63.7;RH-30: 60.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038251 Approved Approved "Cell Junctions" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 68: Oligodendrocytes - Mixed function" "Cell Junctions" "HPA038251: AB_10675790" "unprognostic (1.59e-3)" "prognostic unfavorable (2.24e-4)" "unprognostic (3.25e-2)" "unprognostic (4.08e-3)" "unprognostic (1.81e-1)" "unprognostic (1.93e-1)" "unprognostic (2.29e-2)" "prognostic unfavorable (9.34e-6)" "unprognostic (2.17e-1)" "unprognostic (1.78e-1)" "unprognostic (1.68e-2)" "unprognostic (6.93e-2)" "prognostic unfavorable (5.05e-8)" "unprognostic (3.32e-2)" "unprognostic (9.21e-3)" "unprognostic (9.33e-2)" "prognostic unfavorable (2.14e-5)" 10.9 4.5 9.9 4.7 13.9 1.4 18.6 20.8 10.6 7.7 6.3 3.4 2.0 8.5 3.2 6.7 5.8 4.8 4.0 9.7 12.4 4.4 1.6 3.8 3.6 22.0 16.8 11.2 3.8 1.3 5.1 2.3 18.5 11.2 2.1 1.1 20.6 4.1 5.6 13.7 3.5 5.4 15.8 2.1 3.7 3.5 14.8 3.5 3.3 3.0 3.6 5.8 6.8 19.3 11.5 10.7 32.3 19.7 25.2 27.5 24.7 6.5 5.8 14.3 12.7 8.0 7.0 0.0 4.8 7.1 21.4 5.7 10.0 14.6 19.9 1.0 21.1 36.5 6.6 2.3 33.2 8.0 4.0 33.1 63.7 6.5 56.0 5.8 24.3 0.0 9.6 1.3 26.7 6.4 0.0 1.8 13.3 1.2 18.4 0.0 60.3 3.5 2.5 1.6 11.0 24.8 11.3 12.2 36.6 12.5 16.9 10.6 24.7 17.0 15.3 1.4 21.8 0.7 0.0 0.0 8.6 9.6 31.3 1.4 4.8 0.5 0.0 4.5 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.1 0.0 6.4 0.2 0.0 1.8 9.9 13.9 20.8 10.6 9.7 12.4 22.0 16.8 18.5 15.8 14.8 19.3 3.5 0.0 3.2 92.4 0.5 15.4 7.4 3.6 10.8 0.4 31.1 12.1 0.6 0.0 1.7 0.0 0.0 2.6 0.7 0.2 0.0 3.8 13.0 1.2 10.8 15.4 0.0 2.5 68.6 1.1 13.1 9.1 0.5 0.9 0.0 11.4 25.4 0.6 4.0 0.0 8.4 0.0 0.0 15.4 4.9 22.6 9.6 9.5 7.2 104.9 6.2 0.9 0.0 308.6 215.5 1.2 0.1 24.8 0.1 20.3 0.0 1.8 0.8 0.1 13.1 21.3 9.9 0.4 3.0 19.3 26.0 1.4 1.1 9.8 0.5 3.4 LENG1 ENSG00000105617 "Leukocyte receptor cluster member 1" Q96BZ8 19 54155161-54159721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 98.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 4.0;HaCaT: 5.7;HDLM-2: 3.6;HSkMC: 2.1;LHCN-M2: 3.1;U-87 MG: 4.1;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043541 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" Nucleoplasm "HPA043541: AB_10961190" "unprognostic (8.75e-2)" "unprognostic (4.36e-2)" "unprognostic (2.72e-2)" "unprognostic (2.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "unprognostic (8.73e-2)" "unprognostic (6.42e-2)" "unprognostic (5.22e-2)" "prognostic favorable (8.12e-4)" "unprognostic (7.51e-2)" "prognostic favorable (3.72e-4)" "unprognostic (2.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.82e-2)" "unprognostic (1.14e-2)" 8.2 8.9 0.2 0.0 0.3 0.1 8.1 0.5 0.3 9.3 0.0 9.4 0.0 8.8 0.2 6.6 9.5 0.0 12.0 0.1 0.2 9.1 8.3 7.1 0.0 0.3 0.3 10.3 10.1 0.1 8.6 0.0 0.9 8.8 0.2 0.2 7.2 0.1 15.2 7.4 8.4 0.0 0.3 11.2 10.0 14.7 0.3 0.1 8.3 0.0 0.1 9.5 7.5 0.5 0.0 0.0 4.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.1 0.0 0.1 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 2.2 0.0 0.6 1.1 0.4 0.5 0.6 0.4 0.9 0.7 0.5 0.6 0.6 0.5 0.8 0.7 0.0 0.4 0.4 0.1 0.2 0.3 0.5 0.3 0.1 0.2 0.3 0.3 0.9 0.3 0.3 0.5 28.8 19.2 8.8 2.3 31.4 20.6 22.1 28.6 11.4 10.1 15.2 14.5 7.8 17.2 17.6 18.4 0.0 27.5 30.9 33.7 23.5 21.5 98.8 23.6 18.6 24.2 27.0 17.7 1.1 28.4 14.6 18.3 10.7 17.6 54.6 15.3 29.3 17.0 30.6 6.7 1.2 27.2 34.6 21.8 23.9 15.6 22.4 22.3 21.4 0.0 26.9 19.4 51.5 1.5 4.7 26.1 28.0 15.1 18.0 15.6 35.9 38.2 26.4 15.6 39.5 14.5 24.8 37.3 31.2 10.8 21.5 42.8 38.7 21.3 18.8 16.7 LGALS3 "GALIG, LGALS2, MAC-2" ENSG00000131981 "Galectin 3" P17931 14 55124110-55145423 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Immunity, Innate immunity, mRNA processing, mRNA splicing" "IgE-binding protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 1194.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 4097.0;Paneth cells: 3445.9;Proximal enterocytes: 4397.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "classical monocyte: 651.4;intermediate monocyte: 544.6;myeloid DC: 397.8;non-classical monocyte: 441.2;T-reg: 251.9" "Group enriched" "Detected in all" 13 "dendritic cells: 397.8;monocytes: 651.4;T-cells: 251.9" "Cell line enhanced" "Detected in many" "ASC TERT1: 1169.3;CAPAN-2: 968.0;OE19: 1613.0;SK-MEL-30: 2329.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA003162, CAB005191, HPA076528" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 1900000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB005191: AB_2136784, HPA003162: AB_1078937, HPA076528: " "unprognostic (1.42e-1)" "unprognostic (9.79e-2)" "unprognostic (1.14e-1)" "unprognostic (3.15e-1)" "unprognostic (2.46e-2)" "unprognostic (3.34e-2)" "unprognostic (1.73e-3)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.28e-1)" "unprognostic (1.08e-3)" "unprognostic (5.97e-2)" "unprognostic (8.52e-2)" "unprognostic (1.44e-1)" "unprognostic (2.96e-2)" "unprognostic (2.65e-3)" "unprognostic (7.60e-3)" 404.5 72.0 111.4 219.8 111.8 346.9 323.1 110.7 148.1 331.4 104.3 1194.1 691.9 162.3 53.8 437.8 223.1 273.0 246.2 110.3 109.4 120.0 27.3 356.1 84.5 118.6 111.9 251.4 79.9 19.8 60.6 141.2 108.6 143.1 875.4 68.3 358.6 177.4 78.6 473.1 853.4 158.8 110.4 61.9 340.7 63.5 125.2 53.0 72.3 105.6 114.1 300.8 273.5 114.0 298.6 96.5 3.3 2.5 581.2 1169.3 344.9 226.7 496.2 64.0 113.2 225.4 968.0 0.7 121.3 272.8 114.6 289.0 6.1 245.4 37.5 357.1 4.4 1.0 104.7 103.8 446.8 1.0 1.1 363.4 375.2 73.9 152.8 145.1 101.5 0.7 1.4 283.1 148.8 218.5 1.3 74.4 5.6 1613.0 271.1 0.7 11.3 22.4 604.8 434.2 7.8 22.6 529.0 0.9 2329.1 16.2 242.8 31.4 180.5 297.8 41.5 112.0 4.4 154.0 535.6 2.8 426.8 18.6 31.8 18.5 651.4 32.4 15.7 544.6 99.7 11.5 58.4 44.2 397.8 4.7 2.5 8.3 28.7 24.2 441.2 9.6 251.9 449.6 111.4 111.8 110.7 148.1 110.3 109.4 118.6 111.9 108.6 110.4 125.2 114.0 1157.4 721.1 359.8 33.3 42.0 631.3 624.1 1278.9 241.9 2.9 307.3 478.7 218.2 258.7 1463.3 119.5 0.0 766.1 38.8 4097.0 673.1 605.9 21.7 636.2 742.7 397.8 173.4 578.1 0.2 1057.8 1051.7 666.3 281.4 846.8 580.5 6.3 64.6 2.3 1137.4 1.7 0.5 1733.8 1778.1 287.8 844.6 44.4 555.7 651.2 848.4 14.0 639.1 300.1 9.2 2.0 0.3 1289.6 3445.9 384.0 77.4 708.4 4397.2 81.3 1506.5 14.7 144.7 220.2 521.0 11.5 6.6 524.8 797.6 483.8 119.5 2.9 1880.1 1139.7 LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1307.1" "Group enriched" "Detected in many" 4 "Distal enterocytes: 4349.4;Intestinal goblet cells: 3767.6;Paneth cells: 3353.0;Proximal enterocytes: 4572.2;Undifferentiated cells: 2684.6" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 205 "OE19: 987.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" 1.6 0.5 0.3 86.1 0.4 0.5 5.5 0.5 0.6 1.4 0.2 1307.1 812.2 3.2 0.2 1.4 2.4 137.1 0.9 0.3 0.3 2.9 79.5 1.2 1.1 0.3 0.3 1.6 31.5 0.0 0.8 0.2 0.3 2.3 933.0 0.2 1.1 2.3 1.6 1.6 691.9 55.2 0.2 4.0 135.2 0.9 0.3 0.3 1.7 0.2 0.4 11.2 1.5 0.4 0.0 0.4 0.1 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 2.2 0.0 987.1 0.0 0.1 0.0 2.5 0.1 4.8 0.2 1.4 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.2 1.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.6 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.4 1.7 3.2 6.5 0.7 10.3 1.1 3.0 0.6 3.4 1.1 3.6 3.0 1.3 770.7 1.0 0.0 0.0 0.8 0.9 4349.4 0.0 267.1 0.2 1.9 1.8 1.2 649.7 0.0 0.3 103.3 0.5 0.8 310.4 5.7 49.0 0.8 1.8 69.0 0.1 1.7 0.3 3767.6 0.0 1.9 0.3 0.0 0.0 1.2 0.0 1.0 3.0 0.8 1.0 0.0 0.7 492.7 3353.0 0.4 0.7 1.8 4572.2 9.3 0.4 2.3 0.0 3.9 1.1 0.3 0.9 0.9 2.7 0.5 11.1 1.1 2684.6 42.4 LGALS8 PCTA-1 ENSG00000116977 "Galectin 8" O00214 1 236518000-236552981 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 322.8;Late spermatids: 222.6;Syncytiotrophoblasts: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 118.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012734, HPA030491" Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA012734: AB_2668720, HPA030491: AB_10602345" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (4.71e-3)" "unprognostic (3.93e-2)" "prognostic favorable (9.40e-4)" "unprognostic (9.96e-2)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.93e-7)" "unprognostic (1.41e-1)" "unprognostic (1.57e-1)" "unprognostic (3.15e-2)" "unprognostic (8.21e-2)" 28.6 14.3 10.8 26.5 11.3 44.4 23.3 12.4 14.1 17.2 11.5 19.9 21.6 16.7 19.6 21.2 13.8 24.8 55.0 12.5 12.6 23.4 49.5 27.0 24.0 12.9 10.9 21.6 21.8 35.0 12.7 41.0 13.5 22.2 19.9 22.9 22.1 21.3 6.8 32.4 24.1 21.8 11.7 42.6 18.9 57.1 11.4 26.3 17.2 9.4 22.8 32.8 15.3 11.7 52.3 27.5 3.6 20.8 46.6 39.0 55.6 38.0 45.4 49.0 59.3 37.6 63.3 1.5 34.8 33.7 26.8 60.3 11.0 54.7 43.2 31.1 7.3 35.5 20.7 68.1 56.9 46.9 78.9 39.6 45.6 41.0 13.8 42.4 52.5 26.4 40.7 25.1 35.7 33.3 23.2 8.4 12.5 4.1 18.5 27.2 0.8 3.0 35.4 80.8 13.1 25.7 24.4 82.3 13.7 2.1 59.0 33.7 39.1 1.0 22.0 29.9 47.7 10.0 7.4 1.0 50.4 65.7 30.9 118.5 37.4 18.7 12.5 32.9 17.8 10.7 18.4 14.1 31.7 6.8 12.2 12.7 16.1 14.2 24.0 14.2 22.5 24.8 10.8 11.3 12.4 14.1 12.5 12.6 12.9 10.9 13.5 11.7 11.4 11.7 44.0 76.9 54.7 12.1 19.3 32.5 28.5 64.9 44.9 28.1 31.7 22.7 55.2 34.3 68.1 14.7 25.0 64.4 33.9 25.3 5.9 61.8 322.8 18.7 21.9 39.9 18.1 19.0 31.5 39.2 53.5 35.2 23.0 20.8 109.4 38.0 46.1 27.1 57.5 38.7 37.0 18.8 57.0 100.5 23.6 222.6 23.6 45.1 7.2 24.4 38.7 6.5 17.5 18.1 16.7 44.0 36.0 13.9 15.1 20.6 26.4 14.5 53.1 19.4 26.3 22.5 19.6 46.8 8.7 21.3 37.1 176.2 34.4 22.8 17.1 24.4 LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 9.0;Cardiomyocytes: 10.5;dendritic cells: 6.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 15.4;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.4" "Cell line enhanced" "Detected in some" "A549: 17.4;CAPAN-2: 15.4;HaCaT: 8.3;HeLa: 3.9" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" 1.1 0.2 2.3 0.4 5.4 1.4 5.1 8.2 1.5 3.7 0.3 1.4 0.1 1.2 2.2 5.0 8.8 6.2 14.7 1.0 7.2 0.8 2.1 3.4 0.8 14.7 7.6 1.8 0.2 0.0 17.5 0.3 8.0 5.9 0.7 0.0 5.3 1.4 0.3 4.1 1.3 0.3 6.1 6.7 0.6 7.2 9.8 0.3 5.1 0.5 0.3 2.9 3.8 2.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.6 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.0 0.0 1.7 9.1 0.0 0.0 0.7 4.8 0.0 0.4 0.0 0.0 0.5 3.4 2.3 5.4 8.2 1.5 1.0 7.2 14.7 7.6 8.0 6.1 9.8 2.0 0.1 0.0 0.0 2.6 0.2 1.3 3.6 0.5 23.3 0.0 1.5 9.0 10.5 0.0 0.6 0.0 0.0 0.9 6.0 0.8 0.0 0.0 3.1 0.0 0.0 0.2 0.0 0.4 1.0 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.4 0.2 0.1 0.0 0.8 1.6 0.0 0.6 0.3 4.1 0.0 0.2 0.0 1.9 0.0 0.0 4.1 0.0 0.2 0.0 0.7 0.0 2.5 0.2 0.1 0.1 0.0 0.0 0.0 0.0 5.6 5.5 3.3 0.3 0.1 0.8 4.3 0.0 2.7 0.9 LHFPL2 KIAA0206 ENSG00000145685 "LHFPL tetraspan subfamily member 2" Q6ZUX7 5 78485215-78770021 "Predicted membrane proteins" Fertilization "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 121.9;Microglial cells: 209.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.9;plasmacytoid DC: 6.3" "Group enriched" "Detected in many" 9 "dendritic cells: 6.3;granulocytes: 7.9;monocytes: 3.9" "Cell line enhanced" "Detected in many" "GAMG: 116.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042402, HPA076743" Uncertain Approved "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA042402: AB_10794276, HPA076743: " "unprognostic (2.19e-2)" "unprognostic (3.86e-2)" "unprognostic (2.00e-2)" "unprognostic (1.09e-1)" "unprognostic (2.40e-1)" "unprognostic (4.45e-2)" "prognostic unfavorable (2.73e-4)" "unprognostic (3.44e-3)" "unprognostic (2.32e-1)" "unprognostic (8.43e-2)" "unprognostic (3.62e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (3.45e-7)" "unprognostic (3.40e-2)" "unprognostic (3.88e-2)" "unprognostic (1.34e-2)" "unprognostic (7.85e-2)" 18.2 18.8 10.9 19.6 11.5 18.4 20.5 12.0 13.4 14.0 15.3 17.7 23.8 18.0 18.9 6.3 9.1 22.6 12.2 10.1 11.1 3.1 6.4 19.7 15.2 17.2 13.7 18.5 11.4 10.4 5.7 14.8 14.9 11.4 17.5 5.5 19.3 24.7 2.7 5.7 21.2 22.0 14.6 4.3 14.8 9.1 18.5 14.8 9.1 4.1 14.4 36.3 10.3 18.7 9.8 36.1 10.6 14.1 63.0 18.0 32.7 11.0 28.0 18.7 32.5 12.8 28.4 24.4 4.8 21.7 116.4 16.6 10.2 11.8 30.6 0.2 9.1 24.3 7.2 21.6 46.5 0.1 0.2 20.7 46.6 57.3 88.4 29.6 44.8 0.9 0.2 17.8 42.9 5.2 0.1 1.4 11.8 7.9 10.3 4.7 15.0 6.8 7.1 42.6 2.0 14.4 17.9 6.6 62.5 22.3 3.9 3.0 29.8 21.7 11.8 60.1 33.2 0.7 0.1 34.1 57.5 0.2 39.7 7.9 3.9 4.0 0.0 1.4 0.1 0.6 0.0 0.0 0.9 0.6 0.0 0.0 0.7 0.0 0.5 6.3 0.1 1.3 10.9 11.5 12.0 13.4 10.1 11.1 17.2 13.7 14.9 14.6 18.5 18.7 13.5 3.2 3.4 20.2 5.7 8.7 7.3 5.2 0.6 6.6 18.2 15.6 3.7 1.5 7.6 7.3 0.0 4.0 20.3 34.8 0.0 9.1 1.5 7.5 26.3 21.4 2.4 10.7 15.8 12.9 2.6 38.1 10.7 14.6 0.0 121.9 35.3 1.4 60.1 3.3 7.9 16.3 6.1 40.4 14.7 1.7 19.3 36.3 10.6 209.9 5.5 5.4 0.0 55.3 4.6 17.0 16.1 33.4 3.3 10.4 29.8 0.7 3.9 2.2 6.6 19.1 13.1 0.7 1.7 1.4 4.8 7.3 1.3 22.1 10.0 12.4 LHX6 LHX6.1 ENSG00000106852 "LIM homeobox 6" Q9UPM6 9 122202577-122229626 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Early spermatids: 77.2;Endothelial cells: 32.1;Inhibitory neurons: 46.0;Late spermatids: 225.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 13.2;K-562: 9.8;NB-4: 18.4;PC-3: 12.3;U-87 MG: 9.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 6.5;basal ganglia: 7.1;cerebral cortex: 7.7;hippocampal formation: 7.2;hypothalamus: 2.2" "HPA047854, HPA058319" Approved Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA047854: AB_2680183, HPA058319: " "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (8.06e-2)" "unprognostic (6.18e-2)" "unprognostic (7.72e-2)" "unprognostic (4.49e-2)" "unprognostic (5.83e-2)" "unprognostic (3.47e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" "unprognostic (9.14e-2)" "unprognostic (5.64e-6)" "unprognostic (1.77e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" 15.9 0.8 10.7 1.9 7.1 0.0 11.8 0.0 6.8 4.5 0.0 3.5 1.1 3.5 0.6 2.1 3.5 2.8 5.9 6.5 9.7 1.6 0.2 3.6 1.0 0.0 0.0 2.0 1.1 0.9 0.3 2.7 0.0 2.5 1.3 0.1 2.3 0.8 2.3 2.7 3.4 3.3 0.2 0.1 2.2 5.6 1.3 0.7 3.3 2.8 1.0 5.6 4.0 3.1 2.7 0.0 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 13.2 3.3 0.0 2.8 0.0 1.1 0.0 1.4 3.6 0.0 0.0 2.1 0.1 1.0 0.6 0.0 2.5 0.6 0.0 0.8 0.0 0.2 0.0 4.7 0.7 9.8 0.0 0.0 2.8 0.0 18.4 2.8 0.4 12.3 0.0 6.2 0.0 2.2 0.0 1.9 0.4 3.3 1.0 3.3 0.5 2.7 0.0 0.8 0.8 1.3 0.0 0.2 0.3 0.2 0.2 9.6 4.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.1 0.0 6.8 6.5 9.7 0.0 0.0 0.0 0.2 1.3 3.1 13.7 0.0 0.0 0.7 0.0 0.1 0.2 3.6 1.8 0.0 1.3 1.5 2.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.2 0.2 0.1 32.1 0.0 2.7 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 46.0 0.0 0.0 0.3 0.3 225.9 1.2 0.1 0.0 5.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.9 2.5 6.7 0.5 0.3 0.0 0.0 0.1 0.0 0.2 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LIMA1 EPLIN ENSG00000050405 "LIM domain and actin binding 1" Q9UHB6 12 50175788-50283546 "Predicted intracellular proteins" "Cholesterol metabolism, Lipid metabolism, Steroid metabolism, Sterol metabolism" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 553.9;Basal prostatic cells: 646.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 523.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023871, HPA052645" Enhanced Enhanced "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 90000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "Focal adhesion sites, Cytosol" "HPA023871: AB_1852875, HPA052645: AB_2681898" "unprognostic (6.22e-2)" "unprognostic (9.39e-3)" "unprognostic (8.13e-2)" "unprognostic (1.42e-1)" "unprognostic (8.08e-2)" "prognostic unfavorable (1.76e-6)" "unprognostic (1.63e-1)" "unprognostic (2.29e-1)" "unprognostic (2.28e-2)" "unprognostic (2.65e-1)" "unprognostic (1.28e-3)" "unprognostic (6.27e-2)" "prognostic favorable (2.79e-4)" "unprognostic (7.12e-2)" "unprognostic (9.26e-3)" "unprognostic (1.46e-1)" "unprognostic (1.43e-1)" 122.2 47.1 11.9 39.9 13.6 4.2 89.4 40.3 16.4 63.3 12.3 125.6 112.1 56.8 33.2 37.1 47.9 69.3 31.9 11.7 13.1 48.7 20.7 62.5 32.6 15.4 13.8 38.6 31.1 31.0 24.0 50.6 17.3 45.7 130.5 32.2 47.2 42.2 21.9 47.3 121.8 48.6 13.3 40.8 96.8 16.2 13.1 38.1 33.3 28.3 33.8 96.7 53.2 16.3 154.3 4.5 47.2 69.7 211.9 211.0 177.7 377.2 264.4 296.9 235.8 57.7 220.2 6.8 34.1 523.4 99.7 170.8 42.8 348.7 258.1 98.1 45.1 64.2 16.2 20.5 135.3 23.2 87.5 142.2 100.8 104.6 297.8 89.0 106.2 28.3 45.6 30.3 96.9 26.5 29.0 7.1 24.3 81.0 20.5 28.7 115.2 2.4 68.7 180.3 35.2 75.4 51.5 102.7 166.6 50.0 49.0 14.1 166.7 126.5 98.0 118.4 62.1 16.5 2.0 28.0 137.6 25.3 55.6 0.2 0.2 1.5 6.6 1.1 2.6 0.2 8.2 8.1 4.9 0.6 3.3 6.0 0.1 5.9 2.7 1.2 15.3 3.0 11.9 13.6 40.3 16.4 11.7 13.1 15.4 13.8 17.3 13.3 13.1 16.3 123.2 44.8 91.2 13.4 4.8 553.9 646.1 175.4 283.4 14.6 62.2 73.0 7.3 61.5 179.1 119.5 160.6 128.1 15.5 413.7 15.6 145.6 67.1 75.7 183.9 91.8 122.8 17.5 12.9 307.6 376.9 170.9 126.9 132.6 24.7 15.9 117.8 19.8 34.4 6.7 30.1 138.0 187.2 11.7 59.3 11.7 75.5 19.3 90.7 41.2 9.9 22.7 28.8 78.9 48.4 219.0 244.5 77.5 6.9 221.6 214.8 22.3 67.8 95.4 65.7 54.9 118.0 30.8 10.4 100.0 291.5 64.0 33.3 62.4 244.3 385.1 LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1" "Group enriched" "Detected in many" 4 "Astrocytes: 271.0;Excitatory neurons: 271.6;Horizontal cells: 132.9;Inhibitory neurons: 220.5;Microglial cells: 167.7;Oligodendrocyte precursor cells: 240.8;Oligodendrocytes: 324.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 37.4;basal ganglia: 43.9;cerebral cortex: 56.1;hippocampal formation: 49.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.9;AN3-CA: 20.1;HAP1: 30.2;HEK 293: 21.0;MCF7: 13.5;NTERA-2: 56.9;SuSa: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 25000 "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA074653: AB_2686706" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (3.77e-2)" "unprognostic (3.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (3.23e-7)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" 3.9 1.1 37.4 1.2 43.9 0.0 3.5 0.0 56.1 4.6 0.0 2.2 1.5 4.5 2.2 0.9 2.7 2.1 11.8 49.1 0.0 4.2 0.8 1.0 0.7 0.0 0.0 2.3 2.5 4.1 1.9 6.7 0.0 1.6 0.8 16.2 3.2 2.0 0.8 2.8 1.7 4.6 0.0 3.3 1.4 5.3 0.2 0.3 2.2 1.4 0.3 2.3 2.9 4.6 0.0 2.1 23.9 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.4 0.0 0.4 0.1 30.2 0.0 0.0 0.0 21.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 13.5 0.0 0.0 56.9 1.3 0.0 0.0 0.0 0.5 0.0 0.0 4.2 1.2 0.1 2.4 4.9 21.6 0.3 0.4 2.1 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 43.9 0.0 56.1 49.1 0.0 0.0 0.0 0.0 0.0 0.2 4.6 2.1 0.0 0.0 271.0 0.0 0.3 0.1 0.0 0.0 21.8 0.7 0.3 7.3 1.5 0.0 0.0 2.1 0.1 0.0 1.8 0.0 0.3 8.6 0.8 3.7 2.3 0.0 0.0 271.6 0.2 0.2 1.8 0.0 0.2 0.0 14.9 4.2 0.0 0.3 132.9 220.5 0.3 0.0 0.0 0.0 16.5 0.3 0.1 3.6 167.7 0.0 51.1 0.0 240.8 324.2 0.2 7.7 0.4 0.0 0.0 0.0 0.0 0.0 19.5 26.3 0.0 21.9 0.2 3.1 0.0 0.1 0.3 0.1 0.5 0.2 0.0 LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "epididymis: 421.0" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Excitatory neurons: 1.5;Inhibitory neurons: 2.0;Microglial cells: 1.9;Oligodendrocyte precursor cells: 2.0" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.5 421.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.6 0.1 0.4 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIPJ "bA425M17.2, LIPL1" ENSG00000204022 "Lipase family member J" Q5W064 10 88586753-88606976 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "testis: 7.0" "Cell type enriched" "Detected in some" 7 "Early spermatids: 67.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048594 Uncertain Approved "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA048594: AB_2680456" "unprognostic (4.79e-3)" "unprognostic (6.77e-2)" "unprognostic (4.80e-2)" "unprognostic (2.36e-1)" "unprognostic (2.70e-2)" "unprognostic (9.33e-2)" "unprognostic (2.90e-3)" "unprognostic (7.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.73e-2)" "unprognostic (1.73e-2)" "unprognostic (6.21e-4)" "unprognostic (9.87e-2)" "unprognostic (9.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.88e-1)" 0.2 0.0 0.2 0.1 0.2 0.0 0.2 1.0 0.3 0.1 0.3 0.1 0.3 0.1 0.9 0.0 0.7 0.1 0.1 0.3 0.3 0.2 0.5 0.1 0.3 1.2 0.5 0.1 0.4 0.0 0.1 0.0 0.5 0.3 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.2 0.4 0.1 0.2 7.0 0.3 0.4 0.6 0.0 0.3 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.3 0.3 0.3 1.2 0.5 0.5 0.4 0.3 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 67.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.0 0.6 0.0 9.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 LMCD1 ENSG00000071282 "LIM and cysteine rich domains 1" Q9NZU5 3 8501807-8574668 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 573.4" "Cell type enhanced" "Detected in many" "Adipocytes: 287.6;Ductal cells: 122.0;Endothelial cells: 161.9;Pancreatic endocrine cells: 114.1;Smooth muscle cells: 112.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "T-reg: 20.5" "Lineage enriched" "Detected in many" 6 "T-cells: 20.5" "Cell line enhanced" "Detected in many" "HHSteC: 88.9;HSkMC: 124.9;hTEC/SVTERT24-B: 93.8;U-2197: 83.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024059 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" No No 6600 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane, Cell Junctions" "HPA024059: AB_1852950" "unprognostic (2.46e-1)" "unprognostic (1.79e-1)" "unprognostic (5.13e-3)" "unprognostic (1.30e-1)" "unprognostic (2.28e-2)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "unprognostic (1.38e-1)" "unprognostic (2.96e-1)" "unprognostic (8.21e-3)" "unprognostic (4.29e-1)" "unprognostic (2.54e-2)" "prognostic unfavorable (8.66e-5)" "unprognostic (3.80e-2)" "unprognostic (1.33e-1)" "unprognostic (1.01e-3)" "unprognostic (3.68e-3)" 131.4 14.3 9.5 45.6 9.5 0.1 97.5 13.5 10.8 27.2 38.8 18.1 9.0 90.3 18.4 36.1 57.8 67.2 90.6 14.0 9.7 33.0 9.7 131.7 17.3 14.0 11.0 65.8 37.7 30.0 8.7 54.5 12.1 34.8 7.0 15.2 42.2 16.8 573.4 28.8 20.1 63.3 13.2 55.6 46.4 11.3 12.6 4.7 18.5 260.9 10.2 110.6 31.5 14.8 9.4 52.0 8.6 6.6 62.0 34.6 8.9 37.9 19.4 20.5 50.0 38.8 11.5 0.0 4.2 44.2 8.8 0.8 4.9 9.9 8.4 16.0 3.6 11.6 3.5 7.6 88.9 0.0 1.1 124.9 0.2 93.8 0.7 11.9 10.1 0.0 0.0 0.0 26.8 6.7 0.0 0.1 16.8 12.0 2.3 0.2 28.2 0.1 19.1 3.6 0.3 21.3 6.4 31.1 20.6 23.9 40.7 0.1 5.0 20.4 40.3 83.0 25.9 5.1 6.2 2.6 4.1 2.9 27.0 0.0 0.0 0.0 0.0 0.4 0.1 2.0 2.9 0.6 3.3 0.3 0.0 0.1 0.0 0.0 0.0 1.0 20.5 0.3 9.5 9.5 13.5 10.8 14.0 9.7 14.0 11.0 12.1 13.2 12.6 14.8 287.6 9.6 10.7 2.0 2.1 31.6 42.1 7.4 9.6 13.0 20.4 17.0 14.7 14.3 13.5 5.5 10.4 3.9 1.7 1.4 3.9 122.0 1.1 9.6 77.7 161.9 12.1 0.0 0.8 48.5 4.2 64.5 7.1 4.8 10.2 44.2 30.7 12.6 3.4 97.6 1.2 2.4 4.1 0.8 47.0 2.3 11.5 3.2 53.4 29.0 9.0 38.9 1.0 4.0 8.7 114.1 0.9 32.4 8.0 8.4 0.3 45.5 12.0 8.0 0.0 57.0 112.9 6.4 9.1 29.0 27.1 4.4 5.3 21.5 4.7 7.5 LMOD2 ENSG00000170807 "Leiomodin 2" Q6P5Q4 7 123655866-123664290 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 39 "heart muscle: 778.4;skeletal muscle: 933.7;tongue: 793.6" "Cell type enriched" "Detected in some" 26 "Cardiomyocytes: 1432.4" "Group enriched" "Detected in some" 20 "head and neck cancer: 3.5;prostate cancer: 1.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "HSkMC: 1.4" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA046370, HPA051039" Enhanced Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "HPA046370: , HPA051039: AB_2681321" "unprognostic (2.55e-1)" "unprognostic (1.14e-1)" "unprognostic (1.43e-1)" "unprognostic (2.38e-3)" "unprognostic (1.18e-1)" "unprognostic (5.50e-1)" "unprognostic (5.69e-2)" "unprognostic (6.98e-2)" "unprognostic (2.13e-2)" "unprognostic (1.43e-3)" "unprognostic (3.37e-2)" "unprognostic (1.51e-1)" "unprognostic (1.82e-3)" 0.2 0.1 0.0 0.0 0.0 0.6 0.5 0.1 0.5 0.0 0.2 0.1 0.0 0.0 0.0 21.2 0.0 0.1 778.4 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.8 0.0 10.2 0.0 0.1 10.0 0.0 933.7 0.4 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.2 0.2 793.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1432.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.5 0.4 9.4 0.0 0.0 0.1 0.0 0.1 27.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.9 7.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 LMTK2 "AATYK2, BREK, cprk, KIAA1079, KPI-2, KPI2, LMR2, PPP1R100" ENSG00000164715 "Lemur tyrosine kinase 2" Q8IWU2 7 98106862-98209638 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 50.7;Excitatory neurons: 114.9;Inhibitory neurons: 69.0;Oligodendrocyte precursor cells: 52.3" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 25.2" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010657, HPA041836" Uncertain Approved "Nuclear speckles,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Centriolar satellite" "Plasma membrane, Cytosol" "HPA010657: AB_1079259, HPA041836: AB_2677698" "unprognostic (7.36e-2)" "unprognostic (3.16e-1)" "unprognostic (1.59e-1)" "unprognostic (2.60e-3)" "unprognostic (2.47e-2)" "unprognostic (2.45e-1)" "unprognostic (2.35e-2)" "unprognostic (1.23e-1)" "unprognostic (4.96e-1)" "prognostic unfavorable (8.03e-4)" "unprognostic (1.23e-1)" "unprognostic (4.65e-1)" "prognostic favorable (1.12e-7)" "unprognostic (1.88e-1)" "unprognostic (3.92e-1)" "unprognostic (2.16e-2)" "unprognostic (6.38e-3)" 3.5 7.0 4.2 3.9 6.2 13.8 3.6 0.0 25.2 4.9 0.0 9.7 8.8 3.9 3.9 9.5 4.1 4.2 12.4 6.0 0.0 6.6 6.2 6.6 3.6 2.1 0.5 5.0 14.8 10.7 7.0 3.1 1.8 5.1 8.0 8.2 7.9 4.0 11.1 9.0 9.8 3.7 0.0 4.6 6.5 5.2 1.2 4.9 5.8 7.0 4.8 5.8 6.2 8.7 12.5 14.5 11.0 11.4 5.8 4.6 10.2 5.1 5.5 4.9 5.9 11.5 11.1 6.5 14.3 6.5 18.6 13.4 12.8 7.8 7.6 9.4 9.0 4.4 13.0 11.6 7.0 8.0 7.6 3.2 10.5 10.1 13.6 4.9 7.4 7.4 11.8 13.4 4.5 16.9 8.5 4.8 13.4 17.1 7.0 9.2 7.5 13.0 8.2 21.7 7.8 15.7 10.2 18.4 7.4 11.0 5.1 3.2 9.2 10.2 16.6 20.5 11.7 5.9 11.2 12.8 6.8 6.2 12.3 0.5 0.1 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.2 0.3 0.4 1.4 0.1 0.3 0.2 0.2 0.1 4.2 6.2 0.0 25.2 6.0 0.0 2.1 0.5 1.8 0.0 1.2 8.7 6.0 28.9 17.0 28.7 7.8 9.7 4.3 6.2 14.8 14.2 5.5 3.9 22.4 15.7 11.8 1.8 14.6 2.8 7.5 50.7 1.9 6.1 1.1 13.2 7.6 5.7 12.0 8.4 114.9 9.1 1.9 5.4 21.4 26.4 2.5 5.3 2.5 8.4 2.2 6.7 69.0 14.7 4.1 1.6 2.3 2.0 1.8 3.2 1.8 16.9 2.8 6.1 7.2 52.3 29.6 10.3 23.8 4.5 12.9 8.8 14.0 3.0 15.8 10.6 0.0 8.6 5.7 6.9 6.3 15.5 10.9 3.0 8.6 2.7 14.7 20.5 LMTK3 "KIAA1883, LMR3, PPP1R101, TYKLM3" ENSG00000142235 "Lemur tyrosine kinase 3" Q96Q04 19 48485271-48513935 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 44.0" "Cell type enhanced" "Detected in many" "Club cells: 41.4;Excitatory neurons: 37.0;Inhibitory neurons: 38.8;Urothelial cells: 49.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 9.4;SK-BR-3: 16.4;U-266/70: 9.8;U-266/84: 9.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040203, HPA077070" Enhanced Supported Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Nucleoplasm "Cell Junctions" "HPA040203: AB_10671690, HPA077070: AB_2732330" "unprognostic (2.41e-1)" "unprognostic (1.48e-1)" "unprognostic (5.37e-2)" "unprognostic (5.45e-2)" "unprognostic (2.95e-1)" "unprognostic (1.71e-2)" "unprognostic (5.67e-2)" "unprognostic (2.46e-1)" "unprognostic (2.09e-1)" "unprognostic (2.51e-3)" "unprognostic (5.71e-2)" "unprognostic (1.47e-1)" "prognostic favorable (3.18e-8)" "unprognostic (1.38e-1)" "unprognostic (3.22e-2)" "unprognostic (3.24e-1)" "unprognostic (6.11e-2)" 0.0 1.7 23.1 0.7 27.5 0.4 0.7 6.1 44.0 0.6 0.0 0.2 3.7 0.1 1.1 0.6 0.3 0.4 0.3 31.7 6.7 1.1 0.0 1.3 1.1 9.9 1.2 0.1 0.8 3.6 5.7 0.6 1.5 1.5 0.0 2.7 2.6 1.1 0.0 0.8 1.9 0.0 0.7 0.6 1.2 0.2 8.4 0.4 0.8 0.0 0.8 0.2 0.0 21.8 6.0 4.4 0.5 0.5 0.0 0.0 5.1 0.1 0.4 0.0 0.2 3.7 5.2 1.6 1.5 0.0 1.4 3.0 0.8 1.9 0.0 0.7 2.8 0.2 2.5 0.9 0.0 0.0 9.4 0.1 1.1 0.3 0.0 2.0 0.0 5.0 1.6 3.6 0.0 7.9 1.1 4.1 1.2 3.4 1.5 4.8 0.0 2.1 1.7 1.2 1.5 2.9 0.2 16.4 0.9 1.2 5.6 0.2 0.1 0.0 1.5 0.1 0.0 9.8 9.3 1.9 0.3 4.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.4 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.4 0.0 23.1 27.5 6.1 44.0 31.7 6.7 9.9 1.2 1.5 0.7 8.4 21.8 0.3 3.2 1.7 11.8 2.1 0.5 13.1 17.0 2.8 15.9 20.5 6.2 2.7 2.8 41.4 7.3 0.0 4.9 0.6 0.4 25.4 21.5 0.1 8.4 0.6 0.5 0.0 0.0 37.0 0.4 2.8 0.9 6.6 8.1 0.0 0.6 1.4 0.4 1.3 18.5 38.8 1.2 8.2 0.6 0.9 0.2 0.6 0.4 3.6 1.9 0.2 6.9 0.0 26.2 9.6 17.2 0.1 0.0 14.5 18.8 3.0 0.6 25.9 2.2 0.0 0.4 3.3 4.0 3.3 7.1 1.8 6.8 1.3 2.9 1.5 49.5 LNX1 "LNX, MPDZ, PDZRN2" ENSG00000072201 "Ligand of numb-protein X 1" Q8TBB1 4 53459301-53701405 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 77.5;Early spermatids: 171.7;Excitatory neurons: 123.8;Glandular and luminal cells: 83.0" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 9 "amygdala: 2.7;basal ganglia: 6.0;cerebral cortex: 10.3;hippocampal formation: 7.5;white matter: 3.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 17.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002235, HPA071091" Approved Supported "Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Cell Junctions" Cytosol "HPA002235: AB_1079261, HPA071091: AB_2686344" "unprognostic (4.95e-2)" "unprognostic (1.74e-2)" "unprognostic (2.00e-2)" "unprognostic (3.16e-2)" "unprognostic (2.79e-1)" "unprognostic (2.31e-1)" "unprognostic (1.31e-1)" "unprognostic (5.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.06e-1)" "unprognostic (5.18e-2)" "unprognostic (8.56e-2)" "prognostic favorable (3.08e-7)" "unprognostic (2.67e-1)" "unprognostic (5.49e-2)" "unprognostic (6.81e-2)" "unprognostic (3.05e-2)" 21.9 2.5 2.7 2.1 6.0 1.0 14.3 0.1 10.3 6.1 0.0 6.7 9.4 4.2 0.6 24.4 6.4 5.5 8.7 7.5 0.1 10.6 4.4 2.7 2.1 0.0 0.1 2.1 16.3 11.9 4.3 24.6 0.4 5.9 6.9 3.8 25.1 7.2 5.9 11.8 9.0 3.0 0.0 0.9 9.5 4.4 0.6 3.3 17.9 12.0 4.1 4.3 7.9 3.1 1.4 0.5 1.6 0.9 2.7 5.8 8.0 1.2 0.6 0.0 0.0 2.9 8.9 1.7 1.1 4.3 0.4 1.4 0.0 0.2 0.0 0.4 4.6 2.2 1.5 1.5 1.3 2.4 0.7 4.4 0.2 0.3 0.0 1.9 2.7 0.8 1.9 0.8 6.4 4.5 2.2 1.7 4.3 17.7 0.7 1.2 0.6 0.7 5.6 8.2 2.2 2.1 0.6 10.8 0.9 9.1 5.7 1.1 7.8 10.0 2.6 3.1 1.6 3.6 0.5 1.1 8.7 2.0 1.5 0.3 0.0 0.0 0.1 0.1 0.2 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.0 0.7 0.4 0.2 0.2 0.0 2.7 6.0 0.1 10.3 7.5 0.1 0.0 0.1 0.4 0.0 0.6 3.1 77.5 0.0 3.9 4.9 1.7 8.2 18.0 14.5 24.5 7.5 13.3 7.1 1.6 12.8 15.5 7.3 6.2 30.6 1.5 18.5 19.6 13.7 171.7 37.7 7.6 16.0 13.8 3.6 123.8 11.7 22.1 4.8 14.3 83.0 2.5 1.5 2.9 6.2 2.5 42.1 42.2 13.4 14.2 0.3 2.1 47.9 4.4 1.3 5.4 11.2 0.4 2.2 2.1 43.7 4.0 12.3 26.5 8.6 0.9 8.5 14.5 2.9 17.9 5.8 0.0 10.0 2.2 0.9 2.6 32.2 11.9 14.9 1.9 1.4 14.2 15.2 LNX2 "MGC46315, PDZRN1" ENSG00000139517 "Ligand of numb-protein X 2" Q8N448 13 27545913-27620529 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 59.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040698 Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 15: Hepatocytes - Hemostasis" Vesicles "Plasma membrane, Cytosol" "HPA040698: AB_10673138" "unprognostic (4.97e-2)" "unprognostic (1.97e-2)" "unprognostic (3.29e-2)" "unprognostic (1.47e-1)" "unprognostic (1.15e-1)" "unprognostic (2.65e-2)" "unprognostic (1.12e-1)" "unprognostic (8.38e-2)" "unprognostic (1.16e-1)" "unprognostic (9.27e-3)" "unprognostic (4.21e-2)" "unprognostic (8.79e-2)" "prognostic favorable (7.09e-13)" "unprognostic (4.18e-3)" "unprognostic (1.67e-1)" "unprognostic (2.21e-1)" "unprognostic (2.84e-2)" 3.2 6.7 2.0 3.7 2.3 3.8 6.9 5.1 3.0 4.0 6.5 10.7 14.2 3.0 4.8 10.6 4.6 7.9 8.7 2.4 2.8 7.9 20.5 11.5 4.0 1.7 1.8 4.3 19.6 7.1 3.2 3.7 1.7 6.4 10.5 8.0 9.4 4.8 5.9 6.6 13.4 3.8 1.9 3.1 9.9 12.3 2.4 7.8 9.9 5.9 5.1 6.2 6.7 1.9 6.4 3.5 6.5 7.2 6.7 3.1 6.8 5.6 4.9 5.4 4.9 12.7 12.5 9.6 4.7 4.9 9.8 12.0 11.8 15.0 7.0 6.0 4.9 12.3 7.2 9.3 10.5 6.6 7.6 2.6 22.8 3.8 14.7 15.4 9.9 9.9 3.8 3.6 7.9 7.9 10.0 4.4 7.2 29.0 3.9 9.2 12.7 5.0 11.9 11.1 16.7 3.5 7.6 15.4 10.1 8.0 10.7 5.2 12.6 3.1 4.3 3.1 4.6 3.5 6.3 9.9 2.0 6.3 4.4 2.0 0.3 0.9 0.5 0.1 0.7 0.5 0.6 0.7 0.3 0.5 0.6 0.6 0.3 1.1 0.2 0.1 1.0 0.2 2.0 2.3 5.1 3.0 2.4 2.8 1.7 1.8 1.7 1.9 2.4 1.9 4.5 32.1 27.6 9.8 5.6 25.4 27.7 15.8 23.9 8.9 13.3 7.6 11.4 25.8 11.4 20.2 2.1 1.5 5.5 27.8 3.9 10.2 16.4 11.0 2.7 7.2 10.2 18.9 23.2 14.2 8.1 3.2 11.7 14.7 1.3 10.8 9.3 59.2 2.3 5.0 8.0 17.0 8.2 5.0 7.7 7.3 2.8 2.8 10.6 21.5 2.3 4.4 5.2 3.0 6.7 11.0 23.5 3.4 5.4 16.8 17.8 7.8 15.9 16.3 0.0 3.1 3.5 15.6 17.5 14.8 22.0 3.0 5.5 11.1 11.9 20.9 LONRF1 "FLJ23749, RNF191" ENSG00000154359 "LON peptidase N-terminal domain and ring finger 1" Q17RB8 8 12721906-12756073 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 56.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023584, HPA024814" Uncertain Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 2: Karpas-707 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Centrosome "HPA023584: AB_1853233, HPA024814: AB_1853235" "unprognostic (2.59e-1)" "unprognostic (2.17e-3)" "unprognostic (1.35e-2)" "unprognostic (3.56e-1)" "unprognostic (9.09e-2)" "unprognostic (3.96e-3)" "unprognostic (3.13e-1)" "unprognostic (5.78e-2)" "unprognostic (2.74e-3)" "unprognostic (1.18e-1)" "unprognostic (5.83e-2)" "unprognostic (3.39e-1)" "unprognostic (5.46e-3)" "unprognostic (8.97e-2)" "unprognostic (8.90e-2)" "unprognostic (3.08e-3)" "unprognostic (1.15e-1)" 16.2 5.8 2.8 4.5 2.7 5.9 10.5 3.4 3.7 11.4 1.3 7.7 2.3 11.3 9.6 13.0 10.5 9.5 4.9 3.0 2.3 6.3 9.9 7.3 7.1 2.2 2.1 15.2 7.5 8.0 3.8 10.1 1.9 10.7 4.3 7.9 8.0 10.6 17.2 28.7 4.5 9.2 2.3 8.4 5.4 15.8 2.6 6.8 8.7 11.3 8.1 7.9 8.3 3.0 1.2 3.0 15.0 4.6 15.6 7.4 10.0 3.8 6.3 4.1 5.7 0.9 3.9 24.0 0.9 6.7 12.9 1.8 12.0 4.7 4.6 3.7 6.8 7.9 0.5 6.2 14.4 2.1 3.0 7.0 8.2 2.6 8.9 3.8 6.4 9.7 1.1 56.6 2.7 4.2 10.4 7.0 15.5 4.8 0.9 5.8 10.2 4.3 3.5 10.2 31.2 3.6 2.2 5.1 29.8 10.7 1.0 10.4 2.9 2.2 3.7 8.9 3.0 4.3 20.7 12.4 12.0 7.2 7.0 0.0 0.1 0.6 0.1 0.5 0.3 0.2 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 0.5 0.2 0.0 0.0 2.8 2.7 3.4 3.7 3.0 2.3 2.2 2.1 1.9 2.3 2.6 3.0 18.9 9.6 16.3 23.2 25.2 60.8 32.8 7.8 52.3 25.1 15.1 10.3 9.7 10.0 13.1 11.0 16.7 3.6 6.3 4.3 7.9 5.3 57.4 12.1 27.9 15.1 2.4 4.6 67.0 4.0 8.2 24.2 5.6 28.3 6.3 27.8 6.1 14.7 5.6 8.4 43.6 6.4 4.1 9.5 27.6 53.5 29.2 17.2 44.4 21.5 3.6 8.3 0.0 42.7 14.9 4.3 6.4 19.9 16.3 26.4 3.8 6.0 8.7 13.0 19.7 36.7 32.7 8.2 19.7 26.4 73.6 7.3 9.7 3.4 5.8 30.1 LONRF3 "FLJ22612, RNF127" ENSG00000175556 "LON peptidase N-terminal domain and ring finger 3" Q496Y0 X 118974614-119018355 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.9;Gastric mucus-secreting cells: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Cell line enhanced" "Detected in many" "GAMG: 12.2;K-562: 13.8;OE19: 15.2;PC-3: 16.0;SiHa: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050422, HPA061162" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA050422: AB_2681122, HPA061162: AB_2732658" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (4.24e-2)" "unprognostic (1.64e-1)" "unprognostic (6.06e-3)" "unprognostic (1.29e-2)" "unprognostic (3.21e-1)" "unprognostic (8.01e-2)" "prognostic unfavorable (4.32e-4)" "unprognostic (4.29e-2)" "unprognostic (2.31e-3)" "unprognostic (6.34e-2)" "unprognostic (6.16e-2)" "unprognostic (1.70e-1)" "unprognostic (1.27e-3)" 3.3 3.3 1.2 1.9 1.1 4.5 1.4 6.6 2.8 1.5 0.0 3.5 2.3 1.9 1.2 1.4 2.0 2.4 2.3 3.3 1.0 2.8 12.7 6.4 0.8 0.9 1.9 1.6 7.0 0.7 0.9 0.8 1.0 1.9 4.3 2.8 4.8 2.4 8.8 0.7 2.0 1.5 1.5 0.6 4.0 1.7 2.0 0.3 8.2 3.9 1.0 3.6 0.7 1.1 5.0 6.9 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.7 6.0 0.0 3.5 0.0 12.2 0.0 1.3 0.0 0.1 0.1 3.7 6.6 11.8 6.9 3.7 5.7 0.7 0.0 0.0 0.0 0.0 2.1 1.7 0.5 13.8 0.0 0.9 5.5 0.0 2.3 0.0 15.2 16.0 0.0 3.1 0.0 4.2 2.1 0.2 0.0 14.5 0.4 11.8 0.1 0.0 4.5 0.3 0.1 0.2 0.0 7.9 1.4 6.3 0.0 3.2 5.4 3.4 0.0 0.4 0.0 2.4 0.0 3.8 0.0 1.1 0.8 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.4 0.3 1.2 1.1 6.6 2.8 3.3 1.0 0.9 1.9 1.0 1.5 2.0 1.1 2.2 6.4 13.4 7.8 0.4 1.5 16.9 0.2 1.8 3.3 0.8 1.9 4.4 0.0 6.1 1.8 0.0 0.5 5.3 11.2 1.9 3.0 1.6 4.4 6.4 3.3 1.2 0.4 1.8 4.3 0.0 8.0 17.3 13.0 6.3 0.1 2.2 4.1 2.7 1.7 6.0 4.6 0.0 4.7 7.7 1.0 0.9 9.5 3.6 9.4 0.5 3.7 2.1 3.5 0.2 5.2 8.8 1.5 1.3 7.2 1.6 1.5 0.3 0.3 0.0 9.9 2.0 2.4 4.6 1.6 0.1 0.4 2.7 0.2 3.7 12.5 LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.2;kidney: 6.9;testis: 23.0" "Group enriched" "Detected in some" 70 "Early spermatids: 199.3;Late spermatids: 439.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in some" "basal ganglia: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077128 Approved "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA077128: " "unprognostic (6.95e-2)" "unprognostic (1.88e-2)" "unprognostic (4.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (7.75e-4)" "unprognostic (9.53e-2)" "unprognostic (7.91e-2)" "unprognostic (7.61e-2)" "unprognostic (9.44e-2)" "unprognostic (1.26e-2)" "unprognostic (1.93e-2)" "unprognostic (7.43e-3)" "unprognostic (6.48e-5)" "unprognostic (2.30e-1)" "unprognostic (8.10e-3)" "unprognostic (1.66e-3)" 2.3 0.0 0.5 0.0 3.4 2.8 0.6 0.0 2.1 0.0 0.1 0.1 0.0 0.1 7.2 0.0 1.7 0.2 0.9 0.3 0.0 6.9 0.0 1.0 0.0 0.0 0.1 0.1 0.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.8 0.1 23.0 0.3 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.9 1.2 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 199.3 0.0 0.1 0.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 439.4 1.8 0.3 0.0 0.0 0.3 0.0 0.0 1.5 0.6 0.0 0.0 2.2 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 4.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 15.6;Cardiomyocytes: 31.2;Endometrial ciliated cells: 36.9;Glandular and luminal cells: 51.6;Respiratory ciliated cells: 18.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 19.0;HBEC3-KT: 22.2;hTCEpi: 25.0;NTERA-2: 20.3;PC-3: 19.0;SK-MEL-30: 24.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA013421 Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" 0.0 1.3 2.4 0.2 3.3 0.3 0.9 2.1 5.1 10.4 2.0 0.5 0.1 2.9 5.9 7.0 36.4 0.5 10.5 3.8 1.7 0.0 0.1 1.5 0.2 8.2 2.7 1.5 10.4 0.1 0.1 1.4 2.6 13.4 0.6 0.1 5.7 1.0 0.4 4.3 0.1 0.1 1.9 0.1 0.3 10.4 2.3 2.3 0.2 0.0 1.0 5.1 5.3 3.2 0.7 0.1 0.0 0.1 0.0 0.0 0.7 0.3 1.7 1.4 1.1 0.0 0.0 0.1 0.3 0.0 0.0 0.4 19.0 22.2 1.4 0.2 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 25.0 4.8 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 20.3 0.0 19.0 0.0 0.0 0.0 0.0 5.8 1.3 1.1 0.0 0.5 24.1 1.4 0.0 2.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.4 3.3 2.1 5.1 3.8 1.7 8.2 2.7 2.6 1.9 2.3 3.2 0.0 0.0 0.5 12.7 0.0 3.4 15.6 5.6 7.4 0.0 1.8 3.7 31.2 0.0 6.5 0.0 0.0 0.5 0.1 0.3 0.0 0.0 2.9 36.9 3.6 0.5 0.0 0.0 0.2 1.3 0.0 1.2 0.0 51.6 0.0 0.5 0.4 0.0 0.4 0.0 0.1 0.2 2.0 0.0 1.5 2.4 0.6 0.7 1.8 1.9 0.0 0.0 0.0 0.0 0.1 1.0 0.3 0.0 0.0 13.1 0.0 0.0 18.7 0.0 0.0 0.0 1.2 0.7 3.4 7.7 9.1 0.1 1.5 0.6 0.4 13.5 LPAR4 "GPR23, LPA4, P2RY9, P2Y5-LIKE, P2Y9" ENSG00000147145 "Lysophosphatidic acid receptor 4" Q99677 X 78747709-78757094 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8;ovary: 3.6" "Cell type enhanced" "Detected in some" "Astrocytes: 10.1;Fibroblasts: 4.2;Leydig cells: 20.2;Oligodendrocyte precursor cells: 3.5;Skeletal myocytes: 3.6" "Cancer enhanced" "Detected in single" "glioma: 0.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 19 "basophil: 6.3" "Lineage enriched" "Detected in single" 19 "granulocytes: 6.3" "Cell line enhanced" "Detected in some" "AF22: 9.3;NTERA-2: 15.2;RH-30: 6.4;U-937: 3.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA046563, HPA054951, HPA055571" Uncertain Supported "Nuclear bodies,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies, Vesicles" "HPA046563: AB_2732529, HPA054951: AB_2682646, HPA055571: AB_2682853" "unprognostic (1.62e-1)" "unprognostic (3.53e-1)" "unprognostic (1.58e-1)" "unprognostic (5.81e-4)" "unprognostic (3.12e-2)" "unprognostic (4.85e-3)" "unprognostic (2.81e-1)" "unprognostic (2.57e-1)" "unprognostic (6.75e-2)" "unprognostic (6.73e-2)" "unprognostic (8.91e-2)" "unprognostic (4.86e-4)" "unprognostic (2.99e-5)" "unprognostic (9.27e-3)" "unprognostic (1.00e-1)" "unprognostic (3.58e-2)" "unprognostic (6.03e-3)" 0.5 0.0 1.8 0.4 1.3 0.3 0.8 1.1 1.7 0.6 1.1 0.3 0.0 1.1 0.3 0.6 0.3 0.8 0.7 3.0 1.2 0.1 0.1 0.1 0.0 1.8 1.7 3.6 0.4 0.0 0.1 0.0 1.3 0.2 0.4 0.1 0.3 0.1 0.0 0.5 0.3 0.5 2.6 0.1 0.4 0.3 1.1 0.7 0.1 0.3 0.4 0.3 0.2 3.8 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.6 1.0 1.2 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.6 0.0 1.1 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.1 2.1 0.0 0.4 1.7 15.2 0.0 0.2 0.8 6.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 3.4 0.0 2.6 0.0 0.0 0.2 0.0 0.6 1.2 0.0 0.7 0.7 3.7 1.5 6.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.8 1.3 1.1 1.7 3.0 1.2 1.8 1.7 1.3 2.6 1.1 3.8 1.2 0.0 0.0 10.1 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.1 0.8 0.0 0.0 0.1 0.0 0.0 4.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.4 0.5 20.2 0.1 1.8 1.0 0.6 1.0 0.0 3.5 0.1 0.0 0.0 2.6 0.1 0.2 0.0 0.1 0.0 0.0 0.0 3.6 0.4 0.0 0.3 1.5 0.4 0.0 0.4 0.2 0.0 0.2 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.5;tongue: 137.2" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1705.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 36.2 15.0 29.0 14.9 30.6 8.6 36.7 24.2 24.9 25.1 21.9 16.7 11.9 16.6 19.0 40.5 15.6 13.0 20.1 21.0 32.1 14.9 27.0 16.1 22.3 31.8 38.2 31.5 9.9 23.1 34.2 11.7 35.3 13.7 8.5 14.8 27.3 14.1 193.5 13.4 19.7 13.0 14.1 14.8 14.9 57.4 35.0 16.1 14.6 137.2 26.3 19.9 23.1 18.8 16.2 18.0 15.9 34.9 71.4 77.9 7.8 22.2 38.7 14.0 24.3 6.9 15.4 8.2 2.9 18.6 41.6 17.3 17.4 49.2 12.8 32.9 9.8 20.3 11.5 9.7 25.1 14.1 90.1 71.1 21.7 57.9 22.6 41.7 28.0 19.6 27.4 68.3 10.4 6.4 13.5 12.0 16.2 5.5 18.9 18.1 28.6 52.0 36.9 10.0 42.8 33.6 8.0 19.7 51.9 15.0 4.9 7.9 19.5 22.1 19.9 14.4 19.0 108.0 92.0 15.2 31.3 24.7 16.6 11.2 2.9 13.4 10.3 2.3 11.2 7.3 9.9 10.1 2.7 5.1 8.6 7.2 1.1 9.5 2.3 10.3 12.2 3.7 29.0 30.6 24.2 24.9 21.0 32.1 31.8 38.2 35.3 14.1 35.0 18.8 15.6 22.4 56.8 167.8 46.1 19.1 45.1 12.6 18.8 48.6 32.8 22.9 59.6 31.5 43.9 11.0 85.5 8.7 68.0 21.2 7.9 23.0 338.4 27.8 44.4 25.8 36.2 9.7 55.7 28.0 6.0 28.8 19.4 76.5 35.4 13.1 17.5 48.7 8.9 48.8 71.7 25.2 22.4 15.7 39.4 1705.8 119.0 25.5 17.8 21.5 15.4 14.7 66.9 41.7 43.5 36.5 29.7 179.8 76.0 34.9 5.4 4.8 52.0 49.0 32.9 32.4 18.4 20.6 19.7 5.5 11.9 12.3 73.2 26.6 16.3 31.3 LPIN2 KIAA0249 ENSG00000101577 "Lipin 2" Q92539 18 2916994-3013144 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 165.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 154.4;Granulosa cells: 323.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 7 "granulocytes: 23.4;NK-cells: 12.5;T-cells: 12.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015223, HPA017857, HPA030550" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane, Actin filaments" "CAB015223: , HPA017857: AB_1852904, HPA030550: AB_2673519" "unprognostic (7.03e-2)" "unprognostic (1.05e-1)" "unprognostic (2.88e-1)" "unprognostic (1.51e-3)" "unprognostic (1.20e-1)" "prognostic favorable (8.01e-4)" "unprognostic (9.85e-3)" "unprognostic (1.89e-2)" "unprognostic (1.03e-2)" "unprognostic (3.44e-3)" "unprognostic (3.19e-1)" "unprognostic (1.94e-1)" "unprognostic (3.15e-3)" "unprognostic (4.66e-2)" "unprognostic (2.21e-1)" "unprognostic (2.49e-1)" "unprognostic (7.11e-2)" 9.7 9.3 17.9 21.2 19.9 19.8 9.8 14.6 17.4 9.7 16.6 13.9 62.8 9.8 6.7 10.0 9.5 25.7 7.2 16.1 24.2 26.4 165.8 21.2 24.3 22.7 22.0 13.2 16.4 13.5 10.9 15.7 24.2 9.0 12.5 10.7 7.4 8.0 2.7 3.6 39.9 9.6 15.6 20.3 28.1 22.0 28.8 18.9 12.1 3.0 19.2 9.9 6.0 14.3 8.7 12.0 17.1 6.6 31.7 27.4 10.5 17.4 22.8 18.9 16.9 16.7 7.1 5.4 10.8 30.2 30.2 0.2 13.8 6.3 13.2 11.2 2.7 13.3 10.0 19.4 27.2 11.2 17.0 27.4 4.6 18.5 17.2 28.2 23.4 14.8 12.8 3.5 28.2 7.2 15.0 12.0 5.7 13.7 13.1 26.7 14.0 23.2 17.6 20.0 14.4 10.2 18.4 9.1 6.8 10.7 0.0 18.0 31.2 25.3 28.7 31.7 14.6 5.0 7.9 12.3 22.1 12.2 8.1 8.7 2.4 7.8 11.8 1.5 12.1 1.0 9.2 7.2 1.0 1.7 9.1 6.3 23.4 12.5 0.8 1.5 9.2 3.2 17.9 19.9 14.6 17.4 16.1 24.2 22.7 22.0 24.2 15.6 28.8 14.3 17.7 67.3 44.0 55.2 20.4 5.6 9.8 8.5 5.7 35.7 12.1 11.2 11.2 154.4 23.9 38.6 14.6 25.2 41.9 45.3 17.6 11.8 3.3 48.2 33.3 18.9 14.9 138.1 26.3 19.0 11.3 25.4 103.0 64.4 12.6 323.0 19.2 131.1 23.1 116.1 65.6 36.8 16.2 26.8 8.9 11.0 22.7 31.1 8.8 79.6 31.2 16.7 59.8 37.7 21.0 22.2 21.6 31.2 16.1 21.2 92.4 54.9 17.1 16.7 6.6 16.6 20.1 26.5 73.0 0.6 2.0 49.5 58.9 20.3 14.0 14.1 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRFN2 "FIGLER2, KIAA1246, SALM1" ENSG00000156564 "Leucine rich repeat and fibronectin type III domain containing 2" Q9ULH4 6 40391591-40587364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.4;retina: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 111.5;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 49.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 6.4;cerebral cortex: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 1.7;SH-SY5Y: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076660 Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA076660: AB_2686812" "unprognostic (1.93e-2)" "unprognostic (2.04e-1)" "unprognostic (3.61e-2)" "unprognostic (4.58e-4)" "unprognostic (3.10e-1)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-3)" "unprognostic (4.94e-2)" "unprognostic (1.80e-1)" "unprognostic (9.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (2.66e-4)" 0.0 0.3 1.6 0.0 6.4 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.7 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 6.4 0.0 5.9 1.3 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 10.8 0.1 0.3 0.6 0.0 0.1 0.0 62.6 0.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.1 4.2 0.0 111.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 62.8 1.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 3.7 0.0 0.8 0.0 49.8 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 1.9 0.0 1.0 0.0 0.3 0.2 0.0 0.1 0.1 LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 61.3;Respiratory ciliated cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 1500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Vesicles "HPA017267: " "prognostic unfavorable (2.31e-8)" "unprognostic (3.85e-3)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (4.25e-3)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (2.63e-1)" "unprognostic (4.76e-2)" "unprognostic (2.47e-1)" "unprognostic (6.75e-2)" "unprognostic (1.34e-2)" "unprognostic (4.23e-2)" 14.5 18.0 25.2 5.3 25.8 1.4 11.8 18.7 31.5 17.2 13.8 13.1 11.7 11.4 16.4 28.6 22.3 11.3 10.8 26.7 23.3 20.3 10.0 13.6 2.9 23.6 24.9 16.5 19.8 42.8 17.6 12.5 25.0 25.5 12.3 13.5 20.1 13.0 5.2 20.6 9.1 12.0 19.7 4.1 16.3 8.0 26.0 2.4 22.9 4.8 5.9 18.0 20.8 25.0 26.5 22.9 17.2 15.0 37.8 67.2 3.5 27.7 52.1 18.5 22.4 7.3 52.9 0.2 36.7 43.3 79.4 69.4 19.2 47.1 13.3 43.7 19.4 13.3 74.3 30.4 22.6 13.2 0.8 42.8 93.1 23.0 46.5 52.5 28.9 11.8 26.8 11.0 22.3 45.4 0.5 1.3 10.4 52.0 19.6 14.5 25.5 6.4 33.9 53.8 22.4 15.6 86.7 46.3 17.0 8.5 38.8 26.4 21.1 22.6 4.8 48.4 21.3 0.1 8.7 6.3 40.9 12.9 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 25.8 18.7 31.5 26.7 23.3 23.6 24.9 25.0 19.7 26.0 25.0 7.3 6.4 2.8 17.6 0.5 11.3 14.3 17.9 5.7 12.2 10.2 6.0 8.8 12.8 18.3 20.2 2.1 2.1 0.5 7.7 5.9 6.5 27.0 61.3 6.4 7.4 29.4 5.5 42.5 22.7 1.8 20.5 15.3 16.5 0.0 12.4 9.3 9.5 3.6 8.4 44.3 5.0 16.2 1.9 6.2 31.7 16.4 1.7 14.2 11.2 0.1 6.0 0.0 17.6 40.1 19.7 4.2 14.7 0.6 22.2 4.0 7.0 107.7 5.5 0.0 10.0 11.7 14.7 10.4 14.9 14.3 5.6 1.8 15.7 13.2 23.6 LRP12 "FLJ12929, ST7" ENSG00000147650 "LDL receptor related protein 12" Q9Y561 8 104489231-104589258 "Disease related genes, Human disease related genes, Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 42.7;Excitatory neurons: 78.7;Inhibitory neurons: 53.7;Oligodendrocyte precursor cells: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "basophil: 47.0" "Lineage enriched" "Detected in many" 32 "granulocytes: 47.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017245 Uncertain Approved "Nucleoli fibrillar center,Plasma membrane,Mitochondria" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoli fibrillar center, Plasma membrane, Mitochondria" "HPA017245: AB_1857532" "unprognostic (2.17e-1)" "unprognostic (6.80e-2)" "unprognostic (2.20e-1)" "prognostic unfavorable (2.67e-4)" "unprognostic (2.07e-1)" "unprognostic (2.15e-3)" "unprognostic (4.87e-4)" "unprognostic (2.96e-2)" "unprognostic (3.96e-1)" "unprognostic (4.59e-2)" "unprognostic (1.32e-1)" "unprognostic (3.39e-2)" "unprognostic (9.89e-2)" "unprognostic (7.56e-3)" "unprognostic (4.88e-2)" "unprognostic (1.45e-1)" "unprognostic (4.05e-3)" 5.7 4.7 5.1 3.9 8.8 2.2 4.3 4.7 9.4 6.4 3.1 4.8 3.1 16.5 4.0 4.1 5.8 7.5 13.6 13.8 5.3 6.5 1.5 4.6 1.6 1.8 2.3 6.1 4.5 10.0 3.1 5.3 1.1 6.5 4.8 6.1 3.8 5.9 9.3 3.1 3.0 18.5 2.4 3.7 2.8 4.9 3.1 12.9 6.8 17.2 2.3 7.6 3.2 3.9 18.5 10.6 21.1 37.1 23.4 18.4 4.7 51.5 51.3 17.6 24.6 2.4 17.7 0.0 20.2 49.0 21.2 8.1 8.6 22.0 37.7 34.3 8.2 28.7 4.7 0.8 14.4 0.4 22.1 24.8 15.4 29.5 23.7 63.4 9.1 21.9 6.2 0.0 63.9 3.0 26.5 0.6 5.3 1.6 18.2 2.1 20.5 4.0 13.9 0.8 27.0 16.4 16.4 0.7 44.6 15.8 5.0 5.6 25.7 48.1 31.0 15.7 33.6 23.8 20.2 0.2 25.9 0.0 53.9 47.0 0.3 5.8 0.2 0.8 1.4 0.0 1.0 0.1 0.1 0.0 0.2 0.2 0.2 0.8 0.5 0.4 0.1 0.4 5.1 8.8 4.7 9.4 13.8 5.3 1.8 2.3 1.1 2.4 3.1 3.9 4.4 16.0 2.2 42.7 0.2 11.5 6.3 12.3 10.8 17.5 3.9 4.3 11.7 7.2 5.2 14.7 6.2 0.2 1.7 2.0 0.0 4.6 4.3 4.4 16.4 5.9 14.4 2.5 78.7 4.5 0.5 12.6 1.5 5.5 8.2 10.9 4.2 0.8 5.3 28.6 53.7 2.5 10.2 7.9 14.3 2.7 8.7 8.2 7.2 9.4 6.1 3.1 1.0 64.3 25.2 5.1 0.3 9.1 0.1 7.7 1.5 3.8 5.3 8.3 6.6 8.2 11.3 8.5 12.0 3.2 10.9 0.3 3.9 4.5 2.3 5.2 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LRRC34 MGC27085 ENSG00000171757 "Leucine rich repeat containing 34" Q8IZ02 3 169793003-169812986 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 12.8" "Cell type enhanced" "Detected in many" "Early spermatids: 137.9;Respiratory ciliated cells: 129.6;Spermatocytes: 104.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 8.1;HL-60: 8.9;JURKAT: 7.1;NTERA-2: 7.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA035747 Approved Approved "Cell Junctions,Microtubules,Cytokinetic bridge,Mitotic spindle" Yes NA "Cluster 37: B-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 36: HEL - Hemostasis" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Microtubules" "Cytokinetic bridge, Mitotic spindle" "HPA035747: AB_10670120" "unprognostic (1.04e-2)" "unprognostic (5.71e-2)" "unprognostic (5.67e-2)" "unprognostic (5.64e-2)" "unprognostic (9.74e-3)" "unprognostic (5.46e-2)" "unprognostic (9.74e-2)" "unprognostic (8.24e-2)" "unprognostic (6.39e-3)" "unprognostic (2.57e-1)" "unprognostic (6.05e-2)" "unprognostic (1.23e-1)" "unprognostic (8.39e-2)" "unprognostic (1.16e-2)" "unprognostic (3.48e-1)" "unprognostic (3.37e-1)" "unprognostic (2.79e-1)" 1.5 0.4 1.6 0.6 2.1 1.4 1.1 1.6 2.7 0.9 2.8 0.5 0.2 0.7 0.3 0.2 5.5 0.3 1.1 1.2 2.1 0.7 0.2 1.0 0.8 2.1 2.5 0.8 0.2 0.3 2.8 0.2 2.2 0.6 0.1 5.6 0.3 0.7 0.4 0.5 0.4 0.2 2.1 0.7 0.4 12.8 1.9 0.6 0.9 0.4 0.3 0.4 0.4 1.8 2.3 0.4 0.5 0.0 0.9 3.0 0.0 0.9 1.9 2.4 2.1 0.1 0.0 1.5 0.1 0.6 3.1 0.0 1.8 0.0 0.8 0.4 5.6 8.1 0.2 0.0 0.6 8.9 1.8 0.9 0.4 0.8 0.0 0.1 1.6 7.1 0.2 0.0 0.9 0.0 0.8 1.1 7.7 0.0 2.6 4.0 0.0 0.4 2.1 0.2 4.0 3.1 0.5 0.3 0.0 0.2 0.0 4.2 0.5 0.4 0.0 0.3 0.1 0.1 0.1 1.9 3.5 0.1 2.2 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 1.6 0.1 0.1 1.6 2.1 1.6 2.7 1.2 2.1 2.1 2.5 2.2 2.1 1.9 1.8 3.9 3.2 2.6 8.5 1.5 0.4 0.9 5.3 0.0 6.9 0.4 0.9 3.2 0.0 12.9 5.5 37.5 0.2 1.6 0.1 1.9 0.5 137.9 33.8 5.8 3.0 4.2 4.2 15.1 0.2 0.3 5.0 0.5 1.0 1.3 1.0 10.4 0.3 2.4 11.8 12.5 0.4 6.1 0.8 1.2 36.3 10.5 1.2 0.0 3.7 3.8 7.4 0.0 9.5 3.6 0.3 0.0 10.5 0.7 0.4 0.0 3.6 129.6 18.8 0.0 3.6 3.7 104.4 9.2 0.1 0.3 0.5 0.9 1.9 0.2 0.4 LRRC45 MGC20806 ENSG00000169683 "Leucine rich repeat containing 45" Q96CN5 17 82023305-82031151 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 27.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023372, HPA023382, HPA024768" Enhanced Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Centrosome, Cytosol" "Nucleoplasm, Plasma membrane" "HPA023372: AB_1853317, HPA023382: AB_1853318, HPA024768: AB_10602348" "unprognostic (6.69e-2)" "unprognostic (6.10e-2)" "unprognostic (6.86e-2)" "unprognostic (1.38e-2)" "unprognostic (6.92e-2)" "unprognostic (4.41e-3)" "unprognostic (4.70e-3)" "unprognostic (1.23e-1)" "unprognostic (6.10e-2)" "unprognostic (1.78e-3)" "unprognostic (6.17e-3)" "unprognostic (7.46e-2)" "prognostic unfavorable (1.54e-4)" "unprognostic (1.22e-3)" "unprognostic (1.24e-1)" "unprognostic (4.79e-2)" "unprognostic (3.58e-1)" 5.0 6.1 2.3 3.8 2.2 7.0 5.8 7.5 5.4 6.1 2.2 8.7 5.7 5.4 0.9 10.3 9.0 1.6 5.0 2.5 1.9 7.5 18.0 6.4 3.2 3.0 2.8 4.5 10.1 2.0 5.9 2.4 3.0 8.4 1.7 0.6 9.6 2.2 2.5 8.7 8.6 1.2 2.1 9.5 10.5 4.0 2.2 3.1 8.9 0.5 1.5 6.1 6.9 2.3 18.6 20.7 6.2 12.7 2.5 3.3 24.0 12.7 5.2 7.5 6.3 18.6 12.4 13.9 11.2 2.5 7.8 21.3 6.0 7.6 1.7 8.5 38.6 8.8 43.1 25.5 2.1 10.4 21.2 3.3 3.1 4.5 1.2 3.1 11.1 13.0 6.3 6.0 2.0 31.6 23.5 34.5 6.4 15.0 27.4 19.0 12.2 7.8 4.8 16.9 19.1 18.6 5.8 29.9 11.2 3.0 24.4 12.0 6.5 13.1 16.3 20.8 21.9 11.5 3.1 2.1 7.0 8.9 13.9 2.3 1.2 1.5 1.4 0.9 1.4 0.6 1.6 1.6 0.8 0.7 0.8 1.1 0.0 1.1 0.4 1.3 1.4 1.4 2.3 2.2 7.5 5.4 2.5 1.9 3.0 2.8 3.0 2.1 2.2 2.3 3.9 6.4 2.2 4.2 4.1 4.5 5.0 2.9 1.8 5.2 8.5 8.6 2.7 14.3 7.0 3.7 0.0 12.7 7.8 18.1 5.9 7.3 1.5 19.0 3.4 3.7 4.8 10.3 2.5 4.7 27.9 4.8 13.3 5.0 4.5 13.3 7.1 12.6 8.7 5.0 2.9 12.2 4.1 6.3 3.2 4.4 7.2 4.2 8.8 0.0 4.3 5.6 7.2 1.0 1.8 5.8 9.4 6.4 8.5 2.4 10.9 10.2 24.4 4.1 0.0 2.8 5.2 2.3 11.9 6.3 2.4 3.0 7.0 4.9 18.4 3.7 LRRC69 ENSG00000214954 "Leucine rich repeat containing 69" Q6ZNQ3 8 91101832-91219236 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in many" "Early spermatids: 77.3;Late spermatids: 18.0;Microglial cells: 27.2;Oligodendrocytes: 27.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.3;SuSa: 5.2;U-266/70: 16.0;U-266/84: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046337 Uncertain Approved "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA046337: AB_2679626" "unprognostic (1.63e-2)" "unprognostic (1.02e-1)" "unprognostic (4.69e-1)" "unprognostic (3.28e-1)" "unprognostic (2.78e-1)" "unprognostic (3.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.47e-1)" "unprognostic (9.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-6)" "unprognostic (6.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" "unprognostic (8.68e-5)" 0.3 0.5 0.2 0.9 0.6 0.1 0.6 0.6 0.4 0.3 0.8 0.3 0.2 0.2 0.9 0.3 0.2 0.4 0.5 0.2 0.4 0.5 0.3 0.4 1.1 0.8 0.5 0.2 0.3 0.9 0.2 0.4 0.8 0.5 0.7 0.6 0.7 0.3 0.5 1.7 0.4 0.8 0.5 0.7 0.4 2.9 0.5 0.8 0.5 0.4 0.7 0.7 0.3 1.0 0.6 0.6 0.1 0.4 0.6 1.3 1.0 0.3 0.1 0.2 0.3 0.9 0.8 0.9 0.4 0.2 0.1 0.6 0.7 1.1 0.3 0.3 6.3 1.4 1.8 0.4 0.2 0.5 1.0 0.4 1.0 0.4 0.7 0.4 0.1 1.1 1.0 0.5 0.4 0.2 0.3 0.4 0.6 1.0 0.4 0.8 0.0 0.7 0.2 0.7 0.0 0.2 0.0 0.4 1.0 5.2 1.4 1.0 0.5 0.2 0.6 0.1 0.8 16.0 9.5 3.8 0.1 2.1 0.8 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.3 0.1 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.4 0.5 0.0 0.2 0.6 0.6 0.4 0.2 0.4 0.8 0.5 0.8 0.5 0.5 1.0 1.1 0.0 1.1 16.0 1.5 4.7 2.9 1.3 0.6 1.9 1.6 0.6 2.9 0.0 1.5 3.7 4.2 2.3 2.0 1.1 3.9 1.5 77.3 1.2 0.4 2.7 2.4 0.8 5.3 1.2 1.9 1.7 0.0 0.6 0.0 1.0 4.2 0.6 0.9 0.0 6.4 2.2 6.1 1.3 7.0 18.0 2.8 1.6 7.2 27.2 4.2 1.1 2.1 7.5 27.9 1.8 1.6 1.2 0.2 5.3 0.4 0.9 6.1 3.2 0.0 4.7 2.7 4.2 4.0 0.7 5.3 1.0 2.2 0.9 1.7 2.3 LRRC7 "densin-180, KIAA1365" ENSG00000033122 "Leucine rich repeat containing 7" 1 69567922-70151945 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 20.2" "Group enriched" "Detected in many" 20 "Excitatory neurons: 1132.4;Inhibitory neurons: 996.9;Oligodendrocyte precursor cells: 1038.0;Oligodendrocytes: 408.2" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "amygdala: 6.9;basal ganglia: 17.0;cerebral cortex: 20.2;hippocampal formation: 17.7;thalamus: 11.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 12.6;HEL: 44.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA005625 Supported "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA005625: AB_1853340" "unprognostic (2.81e-2)" "unprognostic (1.62e-2)" "unprognostic (1.51e-1)" "unprognostic (2.98e-3)" "unprognostic (2.47e-1)" "unprognostic (1.73e-1)" "unprognostic (1.04e-1)" "unprognostic (3.50e-2)" "unprognostic (4.84e-3)" "unprognostic (2.92e-2)" "unprognostic (1.06e-3)" "unprognostic (1.46e-1)" "unprognostic (5.64e-6)" "unprognostic (1.31e-2)" "unprognostic (1.74e-2)" "unprognostic (5.13e-3)" "unprognostic (2.08e-3)" 0.1 0.2 6.9 0.1 17.0 0.2 0.0 0.0 20.2 0.2 0.0 0.4 0.1 0.2 0.1 0.2 0.0 1.0 1.4 17.7 1.7 0.8 0.2 0.0 0.1 0.0 2.2 0.1 0.8 0.1 0.0 0.2 0.0 0.3 0.6 1.5 0.0 0.1 1.0 0.2 0.2 0.2 0.0 0.0 0.2 1.6 11.4 0.0 2.2 0.0 0.0 0.1 0.1 2.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.4 4.4 0.0 0.0 12.6 0.3 0.0 0.0 0.0 0.6 44.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 4.7 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.9 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.3 0.1 0.0 0.0 0.0 0.0 6.9 17.0 0.0 20.2 17.7 1.7 0.0 2.2 0.0 0.0 11.4 2.9 0.8 0.0 0.0 41.4 2.5 0.8 0.6 0.4 1.8 44.4 0.3 0.3 6.2 2.8 0.2 0.0 2.1 0.4 2.4 0.0 0.0 0.0 29.4 0.5 1.4 1.2 0.0 3.2 1132.4 0.0 0.5 1.8 0.0 1.4 0.0 0.6 2.9 6.5 0.3 6.7 996.9 0.0 0.0 2.8 3.6 6.3 0.6 0.5 5.4 17.8 1.7 1.0 2.1 1038.0 408.2 0.0 0.0 3.0 1.3 0.9 0.0 1.6 0.1 8.3 0.0 1.4 1.5 9.2 3.0 0.5 1.3 0.1 2.3 0.1 0.0 0.1 LRRC9 FLJ46156 ENSG00000131951 "Leucine rich repeat containing 9" Q6ZRR7 14 59919713-60063559 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 5.4;choroid plexus: 12.4;testis: 8.1" "Cell type enhanced" "Detected in some" "Early spermatids: 112.6;Excitatory neurons: 28.0;Inhibitory neurons: 18.0;Late spermatids: 75.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA040965, HPA041381, HPA077675" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "Nucleoplasm, Nuclear bodies" "HPA040965: AB_2677225, HPA041381: AB_2677444, HPA077675: " "unprognostic (1.01e-2)" "unprognostic (2.00e-1)" "unprognostic (4.45e-2)" "unprognostic (2.12e-3)" "unprognostic (2.80e-1)" "unprognostic (2.95e-3)" "unprognostic (1.93e-1)" "unprognostic (3.11e-2)" "unprognostic (1.91e-2)" "unprognostic (4.82e-2)" "unprognostic (3.45e-3)" "unprognostic (6.06e-2)" "unprognostic (2.62e-3)" "unprognostic (8.54e-3)" "unprognostic (8.30e-2)" "unprognostic (1.67e-2)" "unprognostic (2.29e-2)" 0.3 0.1 0.9 0.0 1.6 0.1 0.0 1.0 0.6 0.0 12.4 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 1.0 1.7 0.0 0.0 0.0 0.0 5.2 5.4 0.0 0.0 0.7 0.5 0.0 3.7 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 4.3 0.0 0.0 8.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.6 1.0 0.6 1.0 1.7 5.2 5.4 3.7 4.3 1.9 5.0 0.0 0.0 0.0 6.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 112.6 1.5 0.1 0.1 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 1.7 18.0 0.0 0.0 0.0 0.0 75.8 0.9 0.1 0.0 1.9 0.0 0.8 0.0 5.5 2.0 0.0 0.0 0.7 0.0 0.7 0.4 0.0 2.9 0.2 0.0 0.0 0.0 10.3 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LRRIQ3 "LRRC44, MGC22773" ENSG00000162620 "Leucine rich repeats and IQ motif containing 3" A6PVS8 1 74026015-74198187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 20.4" "Group enriched" "Detected in many" 5 "Early spermatids: 258.5;Late spermatids: 103.6;Spermatocytes: 204.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 7.9;JURKAT: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA030799 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA030799: AB_10601337" "unprognostic (5.94e-3)" "unprognostic (6.00e-2)" "unprognostic (6.49e-3)" "unprognostic (1.63e-1)" "unprognostic (6.62e-2)" "unprognostic (2.78e-1)" "unprognostic (2.27e-2)" "unprognostic (2.27e-1)" "unprognostic (8.17e-2)" "unprognostic (2.44e-1)" "unprognostic (1.12e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (4.65e-2)" 1.6 0.7 0.5 0.7 0.5 0.1 0.7 0.6 0.7 0.2 1.2 0.3 0.2 0.2 0.3 0.1 2.1 0.4 0.3 0.4 0.6 2.0 0.9 0.3 0.7 0.7 0.8 0.3 0.2 1.2 0.5 0.2 0.7 0.4 0.2 0.5 0.7 0.4 0.1 0.1 0.2 0.0 0.6 0.4 0.3 20.4 0.7 1.0 1.5 0.5 0.6 0.2 0.1 0.7 0.2 1.0 0.1 0.4 1.0 0.4 0.6 0.6 0.4 0.8 0.9 0.1 1.4 1.4 1.2 0.1 7.9 0.1 2.1 2.0 1.0 3.5 0.0 1.3 0.3 0.7 0.1 2.3 0.7 0.7 1.0 1.4 0.5 0.3 0.4 4.8 1.1 1.9 1.4 0.0 0.9 0.3 1.1 2.5 0.6 1.1 0.8 1.4 1.2 0.1 1.0 0.7 0.1 0.1 3.1 0.2 0.9 1.3 0.1 0.1 0.7 0.5 1.2 2.0 0.7 1.1 1.5 0.2 1.1 0.0 0.0 0.8 0.9 0.5 1.1 1.6 1.0 1.1 0.1 0.7 0.9 1.3 0.0 0.4 0.1 0.4 1.6 0.3 0.5 0.5 0.6 0.7 0.4 0.6 0.7 0.8 0.7 0.6 0.7 0.7 1.0 0.0 1.5 2.0 2.8 1.1 1.2 4.0 0.0 1.0 2.0 2.8 1.2 2.8 2.6 0.0 4.2 1.7 0.5 0.3 13.7 1.5 258.5 21.6 0.8 0.8 3.0 0.4 4.1 1.7 1.5 0.3 0.0 1.5 0.0 3.2 0.7 1.8 1.3 0.0 3.9 0.6 0.0 0.6 0.2 103.6 1.8 0.5 0.0 1.9 0.8 1.2 2.1 2.0 4.0 0.9 0.1 1.5 0.6 0.9 0.1 6.3 36.0 0.7 0.0 0.2 1.5 204.8 31.3 0.0 0.1 0.3 1.5 3.6 0.7 1.2 LSMEM2 "C3orf45, FLJ38608" ENSG00000179564 "Leucine rich single-pass membrane protein 2" Q8N112 3 50279087-50288114 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.9;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 6 "Late spermatids: 283.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079523 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA079523: " "unprognostic (2.84e-3)" "unprognostic (6.54e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.46e-2)" "unprognostic (2.48e-1)" "unprognostic (6.49e-3)" "unprognostic (1.71e-1)" 0.4 0.4 2.9 0.1 4.8 0.4 0.3 3.1 3.7 1.3 1.8 0.5 0.3 0.7 0.2 0.5 0.7 0.2 23.9 3.2 3.2 0.8 0.2 0.4 0.0 3.7 3.7 1.2 0.2 0.0 0.1 0.1 3.4 0.4 0.1 0.3 0.2 0.4 16.5 0.2 0.3 0.4 2.7 0.2 0.3 3.9 3.8 0.0 0.2 5.5 0.0 0.4 0.8 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.8 3.1 3.7 3.2 3.2 3.7 3.7 3.4 2.7 3.8 6.0 1.0 0.0 0.6 0.7 0.3 1.0 0.2 0.2 0.0 0.2 1.5 0.9 4.4 0.0 0.8 1.8 0.0 0.1 0.3 0.9 0.0 0.1 40.5 3.3 0.6 0.8 0.0 0.0 0.2 0.2 0.1 0.4 0.0 10.1 5.1 0.2 0.0 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.4 283.1 1.2 0.3 1.8 0.0 0.0 0.5 0.0 0.0 2.8 0.2 0.0 0.7 0.0 0.4 1.5 0.1 0.2 0.2 0.0 1.4 4.7 1.8 1.1 0.4 1.3 0.1 0.2 0.1 0.7 0.1 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 37.7;skin 1: 46.4" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.2;Squamous epithelial cells: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" 5.1 5.8 0.4 2.1 0.5 5.4 4.7 0.5 0.4 15.8 0.4 2.7 2.6 3.0 0.8 37.7 4.0 0.9 2.2 0.3 0.3 2.8 4.0 4.7 2.0 1.2 0.4 4.9 4.7 0.2 3.9 1.0 0.5 5.0 0.5 2.1 11.7 1.2 3.0 46.4 5.1 0.5 0.5 13.5 2.7 4.2 0.6 1.7 3.9 0.1 3.2 2.7 21.6 0.8 2.4 3.9 1.6 1.7 0.3 0.5 7.1 0.8 0.4 1.2 0.7 3.1 1.3 2.9 1.4 0.5 1.6 15.0 1.1 2.5 0.8 3.7 4.4 2.0 3.7 1.5 0.4 3.4 3.7 0.5 3.1 1.7 2.0 1.0 0.5 5.3 2.6 3.3 0.5 4.4 1.8 3.5 0.9 0.1 4.7 7.4 1.5 1.7 0.3 2.8 3.1 1.5 1.5 1.8 1.3 1.7 3.4 2.5 1.5 2.3 2.8 3.6 1.3 7.1 2.1 4.7 0.5 5.5 1.8 0.0 0.5 0.3 0.6 0.3 0.3 0.0 0.5 0.5 0.5 0.0 0.3 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.4 0.5 0.5 0.4 0.3 0.3 1.2 0.4 0.5 0.5 0.6 0.8 2.3 0.0 0.0 0.0 0.7 0.3 3.4 0.1 18.2 0.4 0.6 1.3 0.0 0.0 0.0 1.8 0.0 0.2 1.2 0.5 0.0 0.2 0.0 1.9 0.2 1.6 1.8 2.1 0.0 1.4 0.1 0.5 1.5 0.4 0.0 0.2 1.1 1.0 0.7 3.3 0.0 0.4 0.0 1.9 0.0 0.0 0.3 1.8 0.0 0.0 0.2 0.2 1.0 0.0 0.0 0.4 1.2 0.0 3.0 0.4 1.1 0.3 0.7 0.5 0.0 0.3 0.2 0.9 0.2 15.7 0.1 0.3 2.3 0.3 0.8 0.8 LUZP2 ENSG00000187398 "Leucine zipper protein 2" Q86TE4 11 24496970-25082638 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 30.6" "Cell type enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 1890.0" "Group enriched" "Detected in some" 7 "glioma: 3.5;prostate cancer: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 10.9;HAP1: 4.4;HeLa: 1.9;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039007, HPA046161" Enhanced Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted in brain" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA039007: AB_2676307, HPA046161: AB_2679564" "unprognostic (4.49e-2)" "unprognostic (2.74e-2)" "unprognostic (8.63e-2)" "unprognostic (3.50e-1)" "unprognostic (5.22e-3)" "unprognostic (3.38e-1)" "unprognostic (4.88e-2)" "unprognostic (5.67e-4)" "unprognostic (2.40e-1)" "unprognostic (5.66e-2)" "unprognostic (6.16e-3)" "unprognostic (4.09e-2)" "unprognostic (5.18e-3)" "unprognostic (9.41e-3)" "unprognostic (4.18e-2)" "unprognostic (2.17e-1)" "unprognostic (9.64e-2)" 0.3 6.5 8.6 0.1 8.5 0.1 0.5 11.8 8.0 0.1 1.1 0.8 0.1 0.2 0.0 0.1 0.0 0.1 0.1 6.3 15.1 0.2 0.9 0.2 0.0 10.8 30.6 0.0 0.0 0.0 0.6 0.0 17.2 2.4 0.6 1.1 0.1 0.1 0.0 0.1 0.2 0.3 17.6 0.1 0.1 0.5 15.3 0.0 0.0 0.6 0.0 0.3 0.1 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 10.9 4.4 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.0 1.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.6 8.5 11.8 8.0 6.3 15.1 10.8 30.6 17.2 17.6 15.3 16.5 0.3 0.0 0.0 11.4 0.0 0.6 0.1 0.0 1.8 6.9 0.3 1.7 0.6 0.0 0.0 3.7 0.0 0.0 0.1 1.2 0.0 0.0 33.7 0.6 0.7 0.1 0.0 0.0 149.4 0.0 0.1 2.6 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 371.4 1.7 0.0 0.0 0.0 6.4 0.9 0.1 0.0 4.7 0.0 0.3 0.0 1890.0 9.1 0.2 23.9 0.0 0.0 4.5 0.0 0.7 0.0 0.8 0.0 0.4 0.3 0.3 0.6 0.9 0.3 0.1 0.0 2.4 1.5 1.6 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LYN JTK8 ENSG00000254087 "LYN proto-oncogene, Src family tyrosine kinase" P07948 8 55879835-56014169 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.8;lymphoid tissue: 85.4" "Cell type enhanced" "Detected in many" "B-cells: 237.5;Kupffer cells: 183.7;Macrophages: 226.0;monocytes: 182.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 64.4" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 198.4;HMC-1: 193.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001231, CAB004492" Enhanced Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA 770000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" Vesicles "CAB004492: AB_627897, HPA001231: AB_1079286" "unprognostic (7.87e-2)" "unprognostic (4.89e-2)" "unprognostic (9.04e-2)" "unprognostic (3.74e-1)" "unprognostic (8.12e-2)" "unprognostic (2.17e-1)" "unprognostic (5.70e-2)" "unprognostic (1.11e-1)" "unprognostic (2.79e-1)" "unprognostic (8.80e-2)" "unprognostic (3.68e-2)" "unprognostic (7.15e-2)" "prognostic unfavorable (3.43e-4)" "unprognostic (2.13e-1)" "unprognostic (2.72e-3)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" 17.2 7.3 3.9 79.2 4.0 73.8 9.2 7.4 8.7 11.0 7.8 14.2 36.3 6.2 4.8 8.6 10.0 23.5 5.4 4.4 5.5 5.9 14.9 28.2 49.2 9.4 7.2 3.6 9.5 6.3 4.8 23.5 8.3 5.6 13.3 8.9 17.0 9.7 1.6 3.7 31.6 14.2 7.2 85.4 13.3 3.1 9.0 10.4 10.6 4.4 53.1 29.7 5.7 11.2 47.2 24.6 6.9 0.7 0.5 0.0 43.6 34.6 54.7 21.0 15.7 18.0 15.5 41.2 15.0 12.1 15.3 19.3 22.2 23.8 14.6 70.0 19.8 198.4 6.9 5.5 4.0 20.6 193.4 0.8 7.8 0.6 13.6 13.1 27.2 0.0 98.3 90.2 3.0 3.3 0.1 21.5 38.6 72.9 2.1 3.3 9.6 5.0 9.8 24.9 4.5 74.8 17.3 0.1 7.5 44.9 3.4 41.4 33.1 0.0 10.0 0.1 15.0 26.4 13.2 102.4 1.5 38.8 1.7 4.5 12.2 22.7 1.6 28.3 1.3 15.9 0.3 0.6 10.3 16.1 0.2 0.7 64.4 4.3 49.1 16.2 0.0 5.0 3.9 4.0 7.4 8.7 4.4 5.5 9.4 7.2 8.3 7.2 9.0 11.2 21.0 35.3 37.5 27.7 237.5 5.4 23.8 32.4 4.6 6.3 10.3 7.0 2.2 18.6 44.5 9.2 2.1 2.9 130.0 14.5 0.0 21.8 0.9 14.6 26.2 28.1 6.0 40.4 1.1 53.0 65.2 13.6 18.8 15.9 72.8 0.5 22.9 13.2 126.6 0.0 2.5 14.1 14.2 183.7 96.1 2.4 3.4 226.0 5.4 92.8 182.6 54.3 94.7 13.0 1.7 40.7 13.3 1.2 58.9 62.9 26.0 2.1 40.9 2.6 19.7 3.7 6.4 1.2 2.1 4.9 5.8 38.7 25.0 62.5 17.1 82.4 LYPD1 "LYPDC1, MGC29643" ENSG00000150551 "LY6/PLAUR domain containing 1" Q8N2G4 2 132643286-132671579 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 31.2;choroid plexus: 15.4;fallopian tube: 53.5;pituitary gland: 33.7" "Cell type enhanced" "Detected in some" "Ductal cells: 73.8;Exocrine glandular cells: 74.5;monocytes: 62.0;Oligodendrocyte precursor cells: 28.1;Pancreatic endocrine cells: 43.4" "Cancer enhanced" "Detected in many" "ovarian cancer: 57.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "eosinophil: 3.6" "Lineage enriched" "Detected in single" 22 "granulocytes: 3.6" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 41.6;HUVEC TERT2: 32.7;SK-MEL-30: 36.5;U-251 MG: 65.9;WM-115: 140.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA068333 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 1: Pancreatic cells - Digestion" Nucleoplasm "Vesicles, Plasma membrane" "HPA068333: " "unprognostic (9.25e-2)" "unprognostic (7.45e-2)" "unprognostic (1.03e-1)" "unprognostic (1.44e-2)" "unprognostic (1.15e-1)" "unprognostic (2.07e-2)" "unprognostic (6.40e-3)" "unprognostic (5.60e-2)" "unprognostic (8.36e-3)" "unprognostic (1.05e-2)" "unprognostic (6.70e-2)" "unprognostic (2.86e-2)" "unprognostic (1.51e-2)" "unprognostic (1.43e-2)" "unprognostic (1.55e-1)" "unprognostic (1.03e-1)" "unprognostic (6.78e-2)" 0.6 0.8 24.8 0.3 27.1 0.4 0.8 19.5 25.5 0.3 15.4 8.1 0.1 0.9 0.1 1.5 53.5 1.2 0.8 24.2 29.2 5.9 1.0 1.0 0.6 29.9 30.0 1.3 5.1 0.3 33.7 0.0 27.7 0.7 0.2 1.6 5.5 0.1 0.3 0.3 1.6 0.6 27.3 0.3 0.9 0.7 31.2 2.2 0.9 0.1 1.0 0.8 0.6 21.5 0.4 8.6 11.6 0.2 0.0 0.0 0.0 1.9 1.5 6.3 1.4 0.6 1.1 0.0 18.3 5.1 3.0 7.2 0.0 0.0 2.9 0.1 1.8 0.0 4.0 0.0 0.0 0.0 0.2 0.0 0.1 41.6 0.0 1.7 32.7 0.0 0.0 0.1 0.0 0.8 0.0 0.0 11.1 0.2 3.3 0.0 0.0 0.0 15.1 0.2 1.1 2.3 1.8 0.2 36.5 26.8 0.1 0.3 1.5 0.7 17.4 5.9 65.9 0.1 0.0 0.1 10.0 0.0 140.5 0.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.8 27.1 19.5 25.5 24.2 29.2 29.9 30.0 27.7 27.3 31.2 21.5 0.7 0.0 0.0 8.1 0.2 0.1 0.1 0.4 0.0 1.6 2.0 0.9 0.2 2.8 0.2 5.5 0.0 0.0 0.0 0.5 1.9 73.8 5.6 1.4 0.1 0.2 1.8 0.0 0.8 74.5 0.0 2.2 0.0 0.9 0.0 0.1 0.4 0.0 0.1 15.2 4.7 0.0 0.0 0.8 0.7 9.3 4.1 0.1 0.0 0.0 62.0 1.4 0.0 28.1 4.4 43.4 0.0 0.0 0.0 0.1 0.1 4.8 0.3 0.8 0.0 0.2 3.9 2.6 2.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 LYST "CHS, CHS1" ENSG00000143669 "Lysosomal trafficking regulator" Q99698 1 235661041-235883640 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Phagocytosis, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 31.3;retina: 27.9" "Cell type enhanced" "Detected in all" "monocytes: 277.4" "Cancer enhanced" "Detected in all" "melanoma: 11.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 12.2" "Group enriched" "Detected in many" 5 "granulocytes: 12.2;monocytes: 6.1" "Cell line enhanced" "Detected in many" "HDLM-2: 30.8;SK-MEL-30: 27.1;THP-1: 99.5;U-937: 38.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053366, HPA055725" Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" Yes No "Cluster 8: Neutrophils - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA053366: AB_2682129, HPA055725: AB_2682898" "unprognostic (1.56e-2)" "unprognostic (1.54e-1)" "unprognostic (9.92e-2)" "unprognostic (8.85e-2)" "unprognostic (1.96e-2)" "unprognostic (4.32e-2)" "unprognostic (4.11e-2)" "unprognostic (7.79e-2)" "unprognostic (4.08e-2)" "unprognostic (1.95e-1)" "unprognostic (1.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (5.27e-5)" "unprognostic (1.59e-1)" "unprognostic (1.54e-1)" "unprognostic (6.29e-2)" "unprognostic (1.99e-1)" 5.2 2.7 2.0 8.5 2.7 31.3 6.4 10.1 3.3 7.1 9.1 4.5 3.0 4.3 2.7 4.2 3.9 5.1 2.2 2.0 2.5 3.6 5.5 5.5 7.5 2.2 2.6 4.5 2.2 6.2 1.8 4.6 2.5 3.4 4.3 27.9 4.3 3.3 1.7 9.7 3.3 4.4 1.1 10.8 7.7 6.1 3.3 25.7 6.4 3.8 6.5 5.7 5.2 3.4 8.6 1.9 0.9 2.0 12.7 14.4 1.3 3.1 12.5 3.3 3.1 0.0 2.3 1.1 1.2 6.8 7.7 4.1 1.2 1.6 2.9 30.8 2.7 2.8 1.9 0.6 2.3 4.2 3.7 4.8 7.8 4.0 10.0 4.8 2.8 1.3 0.2 1.7 2.6 0.4 5.3 8.7 0.2 1.6 0.9 0.4 1.2 0.0 9.2 9.2 5.4 1.1 3.4 0.2 27.1 1.0 1.2 99.5 5.8 2.4 1.1 2.8 2.8 2.1 0.1 0.2 4.1 38.0 7.0 0.4 2.9 5.7 0.6 3.4 0.8 1.0 0.2 0.7 1.7 1.4 0.2 0.4 12.2 1.7 6.1 0.2 0.2 0.7 2.0 2.7 10.1 3.3 2.0 2.5 2.2 2.6 2.5 1.1 3.3 3.4 66.3 19.2 41.1 71.2 70.9 71.0 89.8 14.6 18.8 67.4 17.6 15.6 11.6 15.7 28.4 11.0 93.8 6.7 77.3 25.0 11.7 6.6 24.6 22.6 23.8 51.2 9.6 21.0 151.5 12.3 5.0 27.0 41.3 22.4 112.5 9.4 26.0 15.4 31.9 52.2 155.9 14.3 28.5 65.6 81.3 17.7 28.0 111.4 120.9 159.3 277.4 25.6 88.6 112.1 81.6 39.6 24.2 21.8 37.3 56.0 12.7 10.9 26.7 162.5 13.1 31.2 22.7 93.3 28.0 18.7 65.1 8.8 71.3 13.6 7.6 98.5 LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.8;parathyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.6;Excitatory neurons: 26.2;Horizontal cells: 20.2;Melanocytes: 19.6;Rod photoreceptor cells: 18.5;Sertoli cells: 65.7;Smooth muscle cells: 15.4" "Cancer enhanced" "Detected in all" "melanoma: 59.2" "Group enriched" "Detected in many" 5 "amygdala: 13.1;basal ganglia: 11.6;cerebral cortex: 14.8;hippocampal formation: 14.5;white matter: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 19.7;SK-MEL-30: 75.0;U-698: 23.2;WM-115: 50.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 23.2;basal ganglia: 66.8;cerebral cortex: 45.5;hippocampal formation: 36.3;olfactory bulb: 26.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoli "HPA006294: AB_1079288, HPA022046: AB_1853455" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (6.27e-2)" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.41e-2)" "unprognostic (9.06e-3)" "unprognostic (6.81e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (9.28e-6)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (6.82e-3)" 3.7 1.7 13.1 1.5 11.6 0.1 3.0 0.0 14.8 2.0 0.0 1.3 0.5 2.9 0.9 5.3 1.6 3.5 5.0 14.5 0.6 4.7 0.7 7.0 1.1 0.0 0.1 1.2 1.5 54.2 2.2 6.5 0.3 2.8 0.4 3.5 1.4 1.1 1.9 4.6 0.9 2.5 0.0 0.5 1.4 7.5 2.3 1.9 2.7 2.0 0.5 2.3 1.7 9.2 0.1 0.0 9.7 8.3 0.0 0.0 1.2 5.0 0.1 4.3 3.7 0.3 0.1 11.1 3.5 3.1 1.6 0.2 0.5 0.2 2.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 1.7 0.9 0.1 1.8 0.0 0.6 0.0 11.7 0.0 0.1 14.4 0.0 19.7 0.1 12.2 0.0 0.0 0.0 15.6 0.0 2.7 0.4 14.8 12.9 0.0 0.0 75.0 8.2 0.1 0.4 0.0 5.1 3.5 0.1 1.5 0.1 0.1 23.2 0.1 1.1 50.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.1 11.6 0.0 14.8 14.5 0.6 0.0 0.1 0.3 0.0 2.3 9.2 3.9 0.0 0.0 1.6 0.0 1.3 0.8 1.0 17.6 1.8 0.3 11.3 4.6 0.0 0.1 0.0 4.2 7.1 0.4 0.0 1.9 0.0 0.5 0.6 1.3 3.2 0.0 0.0 26.2 0.0 2.3 2.4 0.0 0.5 0.0 3.5 0.0 0.0 0.9 20.2 2.9 0.0 2.0 0.0 0.0 0.8 1.2 0.2 19.6 1.9 0.0 0.9 0.0 6.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 18.5 65.7 1.1 15.4 0.2 1.1 7.3 0.1 0.8 1.4 2.5 0.0 0.0 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MACF1 "ABP620, ACF7, FLJ45612, FLJ46776, KIAA0465, KIAA1251, MACF" ENSG00000127603 "Microtubule actin crosslinking factor 1" Q9UPN3 1 39081316-39487177 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" Actin-binding "Disease variant, Lissencephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 1079.0;Cone photoreceptor cells: 779.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013713, HPA068064, HPA068103" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 25000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions, Actin filaments" "HPA013713: AB_10600821, HPA068064: AB_2685946, HPA068103: AB_2685953" "unprognostic (2.71e-1)" "unprognostic (3.14e-2)" "unprognostic (5.18e-2)" "unprognostic (1.02e-2)" "unprognostic (9.00e-2)" "unprognostic (6.19e-3)" "unprognostic (1.32e-1)" "unprognostic (7.40e-3)" "unprognostic (5.45e-2)" "unprognostic (1.23e-1)" "unprognostic (1.34e-1)" "unprognostic (3.98e-1)" "prognostic favorable (2.77e-5)" "unprognostic (1.07e-1)" "unprognostic (1.81e-1)" "unprognostic (8.57e-2)" "unprognostic (4.22e-2)" 69.1 62.5 172.0 27.7 197.5 36.2 54.6 174.6 181.6 65.9 119.1 148.6 18.6 130.3 48.7 46.4 92.0 46.4 127.0 159.7 166.1 85.7 63.8 183.6 35.9 190.2 179.0 92.6 51.2 96.9 69.3 34.6 182.9 68.2 25.1 121.2 57.7 41.6 73.0 121.0 62.6 54.2 155.6 84.9 71.3 50.2 193.2 39.3 73.3 55.2 22.8 80.3 62.7 185.3 48.1 54.9 66.7 29.3 53.8 47.3 29.8 62.2 79.4 38.0 33.7 34.3 56.5 24.4 64.6 84.0 62.1 30.6 12.5 45.7 51.2 43.5 33.1 34.0 43.4 56.5 66.0 30.8 15.9 37.0 46.5 105.1 54.3 83.5 104.7 52.0 63.2 25.7 137.0 16.0 23.3 52.7 95.8 20.0 31.7 38.5 89.6 4.5 206.0 50.8 38.2 38.6 24.9 17.2 62.5 76.3 7.5 37.9 115.1 61.6 48.5 28.8 101.9 19.4 19.7 28.8 101.0 32.6 55.2 7.5 1.3 3.8 12.2 2.7 5.9 2.2 5.8 7.8 1.8 3.8 4.7 6.1 1.3 6.5 2.9 2.5 3.0 2.0 172.0 197.5 174.6 181.6 159.7 166.1 190.2 179.0 182.9 155.6 193.2 185.3 135.3 150.6 128.2 1079.0 68.7 154.4 74.9 43.0 60.3 387.7 52.5 50.9 246.1 61.5 70.7 80.9 779.8 52.6 120.5 35.4 0.0 113.3 9.6 140.6 124.4 164.3 36.1 57.6 320.6 114.6 62.1 108.2 65.2 180.1 77.7 194.3 132.1 47.9 52.1 117.8 367.5 27.2 22.4 59.7 46.3 11.8 43.8 74.8 71.2 342.9 59.0 107.8 158.6 494.6 410.7 193.5 17.7 112.5 81.0 89.7 22.5 20.6 71.3 398.5 105.2 95.5 136.7 62.6 33.7 43.5 191.5 69.9 131.2 76.5 19.7 78.8 MADD "DENN, KIAA0358, RAB3GEP" ENSG00000110514 "MAP kinase activating death domain" Q8WXG6 11 47269161-47330031 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 133.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 80.9;Cone photoreceptor cells: 125.1;Horizontal cells: 132.9;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 33.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 33.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038568 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA038568: AB_10795030" "unprognostic (3.16e-1)" "unprognostic (1.81e-1)" "unprognostic (8.51e-3)" "prognostic favorable (6.62e-5)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (4.82e-3)" "unprognostic (1.16e-1)" "unprognostic (1.91e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.69e-5)" "unprognostic (1.53e-1)" "unprognostic (3.55e-1)" "unprognostic (8.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" "prognostic favorable (8.25e-4)" 15.1 24.6 32.4 17.7 32.2 28.4 14.8 46.7 44.5 16.1 0.3 17.9 12.4 15.1 12.0 11.1 14.0 12.2 24.6 40.5 21.2 17.1 13.0 19.0 20.9 18.2 18.8 18.8 17.5 18.4 65.7 16.0 22.1 20.7 16.6 133.2 16.6 17.1 30.1 22.8 19.0 14.6 7.0 22.0 18.8 28.5 16.7 23.6 14.4 23.4 17.9 18.7 15.0 32.1 14.0 28.7 30.8 27.6 20.6 14.3 6.9 19.3 25.8 24.2 25.9 21.0 12.9 29.6 6.0 21.3 31.1 27.2 25.2 13.6 20.8 33.1 25.6 52.7 55.0 18.3 14.8 36.1 69.4 13.9 14.3 12.7 15.9 16.4 22.4 18.7 34.5 21.1 21.5 19.7 17.2 38.6 18.4 32.8 19.6 23.2 49.5 19.7 12.4 66.0 48.4 31.5 24.9 29.0 17.6 18.1 22.8 27.0 19.2 22.4 14.1 32.3 13.2 24.9 27.9 16.6 20.9 25.1 21.5 33.3 3.4 6.5 5.6 5.6 5.0 4.0 3.9 4.6 5.2 4.2 4.5 3.6 0.9 5.7 7.9 2.7 7.5 6.2 32.4 32.2 46.7 44.5 40.5 21.2 18.2 18.8 22.1 7.0 16.7 32.1 10.6 12.8 9.2 21.5 11.7 10.7 4.1 6.1 6.8 80.9 11.3 10.2 23.4 7.2 5.8 7.3 125.1 4.6 29.0 21.2 0.0 7.5 14.6 5.3 7.0 11.5 16.3 8.6 37.4 4.9 2.3 7.8 23.4 8.3 26.6 13.9 14.6 7.0 11.5 132.9 33.7 17.7 4.1 19.4 14.9 4.9 7.2 14.9 10.6 21.5 11.1 14.4 23.7 14.1 22.4 12.0 12.2 12.8 17.7 8.0 12.2 5.1 6.2 106.8 6.6 8.7 7.7 14.9 23.2 6.7 8.2 4.4 15.4 16.2 13.7 5.9 MAGI1 "AIP3, BAIAP1, BAP1, MAGI-1, TNRC19, WWP3" ENSG00000151276 "Membrane associated guanylate kinase, WW and PDZ domain containing 1" Q96QZ7 3 65353525-66038834 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 497.7;Inhibitory neurons: 809.8;Oligodendrocyte precursor cells: 368.4;Oligodendrocytes: 532.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031851, HPA031853, HPA077002" Supported Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 18: Non-specific - Mitochondria" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" Nucleoplasm "HPA031851: AB_10599289, HPA031853: AB_10602095, HPA077002: " "unprognostic (5.00e-2)" "unprognostic (9.84e-2)" "unprognostic (6.00e-3)" "unprognostic (1.73e-3)" "unprognostic (1.64e-1)" "unprognostic (2.17e-2)" "unprognostic (1.46e-3)" "unprognostic (9.46e-3)" "unprognostic (8.59e-2)" "unprognostic (2.19e-1)" "unprognostic (6.58e-2)" "unprognostic (2.05e-3)" "prognostic favorable (4.55e-8)" "unprognostic (3.51e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-2)" "unprognostic (8.03e-2)" 11.3 5.0 3.7 1.3 4.8 0.0 12.5 6.3 5.9 5.5 3.9 9.7 5.0 6.2 2.0 8.0 5.8 5.3 9.0 4.7 5.3 10.2 13.4 8.8 1.1 3.7 3.8 2.7 12.6 5.9 7.7 5.3 2.6 7.1 4.2 7.0 11.6 4.9 3.8 12.5 6.4 3.1 2.7 11.9 14.7 10.3 4.1 2.0 13.4 4.1 1.8 5.4 7.2 4.9 4.1 2.2 12.3 1.3 2.4 1.7 5.5 7.0 5.9 2.6 4.0 15.1 3.5 0.0 1.0 8.3 2.1 1.2 3.4 2.4 4.1 0.0 1.9 36.1 4.3 10.2 1.5 0.0 1.1 2.7 2.0 8.9 1.8 6.8 6.0 4.7 15.6 0.0 2.8 3.1 0.0 0.0 16.6 12.2 2.1 0.0 3.5 0.9 3.1 13.5 3.9 10.8 2.7 3.3 0.1 8.0 6.4 0.0 1.6 8.2 6.0 2.1 2.9 0.0 0.0 0.0 4.8 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 4.8 6.3 5.9 4.7 5.3 3.7 3.8 2.6 2.7 4.1 4.9 102.8 76.9 29.8 204.7 1.3 22.3 17.7 7.9 26.2 98.3 46.5 37.5 35.6 102.9 22.5 23.9 75.0 20.2 0.5 51.0 3.9 44.3 179.1 35.8 35.5 55.5 36.5 2.7 497.7 31.8 2.4 9.6 47.4 50.8 1.3 78.4 82.5 60.9 4.8 232.2 809.8 40.3 12.2 5.0 3.6 27.0 6.5 1.8 5.4 170.5 0.6 15.2 0.0 368.4 532.1 40.3 25.4 8.6 0.2 14.7 33.2 12.2 40.3 26.4 32.9 7.0 17.5 44.7 12.3 12.7 18.8 5.1 2.7 27.1 26.3 11.9 MAGI3 MAGI-3 ENSG00000081026 "Membrane associated guanylate kinase, WW and PDZ domain containing 3" Q5TCQ9 1 113390515-113685923 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 34.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 266.0;Excitatory neurons: 206.7;Oligodendrocyte precursor cells: 128.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008444 Supported "Cell Junctions" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "HPA008444: AB_2668069" "unprognostic (4.07e-1)" "unprognostic (3.59e-2)" "unprognostic (1.54e-3)" "unprognostic (2.32e-2)" "unprognostic (2.31e-2)" "unprognostic (5.21e-3)" "unprognostic (2.23e-1)" "unprognostic (7.06e-2)" "unprognostic (2.80e-2)" "prognostic favorable (4.29e-4)" "unprognostic (1.09e-2)" "unprognostic (1.03e-1)" "prognostic favorable (2.60e-8)" "unprognostic (1.71e-2)" "unprognostic (7.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.50e-2)" 2.8 3.3 5.4 2.3 7.1 0.2 7.6 2.8 8.6 3.5 2.8 9.2 5.9 4.9 6.5 7.6 3.7 3.8 3.2 5.4 5.4 7.1 6.2 13.2 1.2 4.0 7.4 6.0 10.7 3.9 4.7 7.4 6.6 4.2 8.2 34.8 4.3 2.6 1.5 1.9 7.5 4.6 2.0 2.3 11.6 4.1 5.2 2.4 10.9 2.4 3.8 2.7 4.0 5.9 8.8 10.8 10.0 4.5 4.4 6.4 2.7 6.1 3.0 4.8 5.3 9.5 2.6 0.4 4.5 5.7 4.1 3.9 9.1 4.7 5.9 9.5 8.6 4.0 9.6 4.3 1.0 3.3 5.6 3.4 2.3 5.1 11.0 5.7 6.7 4.2 4.7 8.4 6.6 5.9 5.2 0.9 3.5 15.3 6.3 7.3 16.1 1.0 5.5 4.0 8.9 9.0 7.4 12.1 2.2 12.3 6.3 1.7 11.6 7.8 9.8 7.1 8.7 3.1 2.8 0.0 4.1 1.5 6.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.4 7.1 2.8 8.6 5.4 5.4 4.0 7.4 6.6 2.0 5.2 5.9 14.0 266.0 103.2 106.7 1.3 10.8 9.1 9.2 21.1 97.1 27.1 16.0 9.2 14.3 60.7 12.9 50.1 16.0 1.0 51.8 7.9 10.9 39.4 11.2 19.7 11.9 13.8 3.2 206.7 10.7 2.4 14.9 37.8 15.9 6.3 12.1 12.1 14.4 4.1 40.4 100.1 23.6 4.1 2.2 6.9 28.4 10.2 2.6 12.4 92.8 0.5 35.6 0.0 128.7 17.7 13.5 40.2 11.3 8.8 9.5 32.6 5.3 17.5 45.6 13.1 13.4 10.7 23.8 9.6 23.4 7.5 5.5 4.1 8.7 28.9 10.5 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAP11 "C7orf43, FLJ10925, TRAPPC14" ENSG00000146826 "Microtubule associated protein 11" Q8WVR3 7 100154420-100158723 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Cytotrophoblasts: 7.0;Extravillous trophoblasts: 7.2;Hofbauer cells: 7.7;Syncytiotrophoblasts: 19.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019359, HPA029463, HPA029464" Approved Enhanced "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Vesicles "Plasma membrane, Centriolar satellite" "HPA019359: AB_1848677, HPA029463: AB_10600001, HPA029464: AB_10600205" "unprognostic (1.57e-2)" "unprognostic (1.24e-1)" "unprognostic (6.19e-3)" "unprognostic (2.59e-1)" "unprognostic (5.23e-2)" "unprognostic (1.06e-1)" "unprognostic (9.36e-3)" "unprognostic (5.68e-3)" "unprognostic (6.97e-3)" "unprognostic (1.25e-1)" "prognostic favorable (6.19e-5)" "unprognostic (2.42e-2)" "unprognostic (1.85e-2)" "unprognostic (4.26e-2)" "unprognostic (2.81e-1)" "unprognostic (3.26e-1)" "unprognostic (6.54e-3)" 7.5 13.3 9.4 16.7 9.6 11.9 8.4 9.6 10.7 9.7 7.4 20.0 14.2 11.8 6.4 15.9 9.5 7.1 7.3 10.4 12.1 16.6 17.2 10.7 20.7 11.5 11.4 6.7 13.8 17.6 17.9 7.3 12.3 12.8 11.5 4.9 15.3 8.4 5.6 25.0 22.5 5.7 7.0 32.2 17.8 30.3 12.0 13.9 15.5 3.8 12.4 9.4 10.9 9.4 7.6 9.7 11.1 18.8 6.8 3.7 12.5 13.9 10.8 9.4 6.8 7.6 8.8 9.6 12.4 10.5 14.6 14.4 5.3 11.0 3.6 18.1 10.6 7.3 13.5 6.7 8.1 9.0 32.1 7.5 7.4 9.1 7.0 6.8 8.3 9.7 15.9 16.9 12.4 23.6 20.7 19.3 12.4 14.0 13.9 12.3 5.1 10.7 8.2 8.6 14.0 14.8 12.5 35.7 7.6 7.3 7.2 10.7 11.5 18.6 15.7 24.7 10.9 24.8 25.4 9.7 10.5 12.3 20.2 0.6 0.3 1.4 0.6 0.6 0.5 0.2 0.8 0.6 0.2 0.6 0.4 0.7 1.9 0.2 0.6 0.2 0.0 0.2 9.4 9.6 9.6 10.7 10.4 12.1 11.5 11.4 12.3 7.0 12.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 MAP1S "BPY2IP1, C19orf5, FLJ10669, MAP8, VCY2IP1" ENSG00000130479 "Microtubule associated protein 1S" Q66K74 19 17719242-17734513 "Predicted intracellular proteins" Apoptosis DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.9" "Group enriched" "Detected in all" 4 "Early spermatids: 98.1;Late spermatids: 293.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050934, HPA054637" Approved Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Nucleoli, Cell Junctions" "HPA050934: AB_2681281, HPA054637: AB_2682552" "unprognostic (8.47e-2)" "unprognostic (2.39e-2)" "unprognostic (1.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.70e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (5.29e-4)" "unprognostic (2.53e-1)" "unprognostic (6.17e-2)" "unprognostic (4.39e-2)" "prognostic favorable (2.65e-4)" "unprognostic (6.33e-2)" "unprognostic (1.19e-1)" "unprognostic (1.36e-1)" "unprognostic (1.72e-1)" "unprognostic (2.09e-1)" "unprognostic (8.65e-2)" 20.5 13.9 48.2 8.7 51.9 11.2 19.1 36.8 82.9 18.9 30.1 21.5 7.7 24.8 5.4 11.9 19.2 7.9 18.8 51.4 40.5 15.4 12.4 23.5 9.0 44.7 41.1 21.6 15.6 5.4 22.0 9.7 43.3 17.4 2.4 2.8 19.7 6.5 32.4 12.2 17.7 3.6 39.2 18.3 20.1 74.7 40.6 6.1 16.1 5.4 3.9 21.6 14.6 47.7 30.1 43.2 12.4 16.9 10.4 15.4 34.0 18.3 8.8 10.9 12.3 61.3 16.0 17.3 33.8 11.4 12.8 15.3 10.5 14.5 4.6 21.8 61.1 15.1 36.3 39.2 22.1 16.8 20.9 16.7 8.3 16.7 10.5 7.9 22.6 12.5 24.2 9.5 6.0 39.0 20.8 42.0 28.7 17.1 50.8 33.3 10.2 17.5 14.8 43.4 23.0 26.5 10.7 14.8 18.9 9.0 9.9 17.8 37.3 19.7 18.2 40.7 27.2 18.1 23.3 17.4 23.7 26.7 25.1 18.5 22.6 25.9 15.7 22.2 15.1 15.7 12.3 15.6 25.9 15.5 10.1 13.9 31.4 13.0 17.9 21.2 12.2 19.0 48.2 51.9 36.8 82.9 51.4 40.5 44.7 41.1 43.3 39.2 40.6 47.7 11.1 3.2 7.5 4.2 14.7 10.3 14.0 13.1 13.1 11.1 12.3 8.6 5.5 15.7 12.1 3.7 8.4 21.7 14.0 30.9 3.9 22.2 98.1 12.9 11.5 18.5 20.4 3.8 8.4 17.2 16.9 12.3 19.4 26.9 10.2 12.0 20.7 4.8 26.1 40.4 5.5 16.6 12.2 18.7 25.1 293.2 22.4 20.7 1.8 2.8 17.4 8.1 8.2 4.5 7.1 24.2 15.8 31.6 8.8 14.9 19.0 5.9 6.2 6.3 13.1 7.7 13.0 25.9 21.4 5.4 3.3 33.8 11.3 8.1 18.3 13.7 MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424058-209734118 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 253.3;retina: 411.0" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 875.7;Excitatory neurons: 883.3;Inhibitory neurons: 823.6;Oligodendrocyte precursor cells: 688.6;Rod photoreceptor cells: 514.5" "Group enriched" "Detected in many" 4 "glioma: 30.4;thyroid cancer: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 296.9;NTERA-2: 106.7;SCLC-21H: 148.6;SH-SY5Y: 82.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001984, HPA008273, HPA012558, HPA012828" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "CAB001984: , HPA008273: AB_1853945, HPA012558: , HPA012828: AB_1853946" "unprognostic (2.47e-2)" "unprognostic (2.81e-1)" "unprognostic (2.58e-2)" "prognostic unfavorable (1.98e-6)" "unprognostic (2.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (6.06e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (7.28e-2)" "unprognostic (4.10e-5)" 5.5 11.6 89.2 1.2 115.9 0.3 5.5 2.7 253.3 4.3 0.0 2.9 0.9 2.3 3.9 6.5 2.5 7.6 8.4 135.2 215.6 5.4 3.8 13.5 1.8 37.7 52.2 7.4 10.7 15.5 33.8 0.8 75.3 7.6 1.7 411.0 7.8 4.9 1.7 16.9 1.6 2.8 14.5 1.7 3.3 6.5 123.9 3.5 16.7 4.6 2.4 1.6 5.3 88.2 2.6 0.6 296.9 0.0 3.9 2.2 0.1 1.9 2.1 0.7 2.2 0.0 16.1 0.0 1.7 3.8 14.0 4.1 23.4 1.8 1.0 0.1 1.4 1.2 8.9 0.1 36.7 0.3 0.2 3.1 9.6 0.1 5.8 17.3 7.8 0.1 0.0 3.1 0.3 1.1 0.1 0.0 106.7 0.5 0.5 0.0 0.6 0.3 3.8 0.1 148.6 82.7 6.3 0.9 3.7 34.8 8.2 0.0 0.2 0.3 1.7 0.1 4.1 1.9 0.0 0.0 15.5 0.0 45.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 89.2 115.9 2.7 253.3 135.2 215.6 37.7 52.2 75.3 14.5 123.9 88.2 16.8 96.1 3.2 127.3 1.8 5.9 3.3 12.0 4.6 144.7 6.2 8.0 4.9 27.1 3.7 5.5 875.7 0.4 0.1 0.0 3.9 26.8 22.1 2.2 1.1 15.7 32.4 2.7 883.3 11.0 0.1 5.3 3.6 4.4 1.3 1.6 18.5 0.4 0.5 33.7 823.6 0.2 6.1 1.4 1.5 10.7 28.6 1.4 19.6 74.0 0.0 129.7 0.0 688.6 53.8 10.0 0.0 15.4 0.1 12.3 0.0 0.4 3.4 514.5 32.9 5.1 26.1 6.6 22.7 2.3 6.5 0.3 0.3 6.6 0.0 0.7 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP2K4 "JNKK1, MEK4, MKK4, PRKMK4, SERK1" ENSG00000065559 "Mitogen-activated protein kinase kinase 4" P45985 17 12020829-12143830 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 226.9;Inhibitory neurons: 189.3;Oligodendrocyte precursor cells: 148.3;Oligodendrocytes: 203.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 10.4" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 5 "SuSa: 177.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007751, HPA060074" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Cell Junctions" "CAB007751: , HPA060074: AB_2684197" "unprognostic (1.55e-1)" "unprognostic (1.85e-1)" "unprognostic (4.47e-2)" "unprognostic (1.02e-2)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "unprognostic (2.89e-1)" "unprognostic (2.16e-1)" "unprognostic (1.93e-3)" "unprognostic (2.53e-1)" "unprognostic (2.76e-3)" "unprognostic (4.82e-2)" "unprognostic (5.32e-3)" "unprognostic (3.13e-1)" "unprognostic (2.30e-1)" "unprognostic (7.00e-2)" "unprognostic (1.79e-1)" 11.4 13.1 27.3 10.1 30.2 3.6 14.5 18.7 44.8 12.0 8.7 12.0 10.1 12.1 17.5 18.8 11.4 10.9 15.8 32.7 28.5 16.2 21.8 11.7 11.7 30.0 21.8 12.6 11.5 19.4 13.8 15.8 30.9 14.3 13.1 15.4 10.5 12.7 24.1 15.1 10.5 13.8 19.0 11.6 11.2 11.0 25.9 15.2 16.7 28.2 14.4 14.7 13.0 30.1 31.1 26.2 33.8 17.5 18.3 23.5 21.3 20.6 27.1 23.1 21.9 15.6 10.4 12.8 16.4 32.4 15.2 20.2 29.7 28.8 34.3 22.7 33.7 14.2 14.1 29.8 21.4 13.7 20.5 19.6 27.9 27.0 28.0 23.9 21.3 17.8 15.4 7.3 29.4 11.5 16.8 12.9 19.6 33.2 12.4 20.3 37.8 8.9 31.6 19.7 6.8 19.9 23.8 12.7 20.3 177.7 16.1 10.0 19.6 11.3 17.4 15.8 24.9 14.2 16.9 9.9 21.3 10.7 16.8 0.4 2.1 1.7 2.2 1.2 1.9 2.1 1.8 1.8 1.5 2.7 1.5 2.4 10.4 2.7 3.9 1.5 2.2 1.8 27.3 30.2 18.7 44.8 32.7 28.5 30.0 21.8 30.9 19.0 25.9 30.1 13.9 9.6 19.4 71.8 27.1 41.4 36.1 12.7 66.0 15.3 20.4 16.3 22.6 7.2 18.3 14.7 8.4 12.6 17.7 19.1 25.4 12.3 7.2 16.9 16.4 12.0 12.0 14.5 226.9 14.3 10.3 19.4 42.3 27.3 1.3 20.1 11.0 20.8 11.7 18.5 189.3 13.1 20.3 19.9 14.7 8.9 11.8 15.4 12.4 68.4 24.1 11.3 14.4 148.3 203.0 16.9 9.3 12.8 26.9 37.7 11.0 25.2 8.6 10.0 13.1 19.2 20.2 7.3 9.3 56.7 39.2 25.3 20.7 15.0 13.3 41.5 MAP2K7 "Jnkk2, MKK7, PRKMK7" ENSG00000076984 "Mitogen-activated protein kinase kinase 7" O14733 19 7903843-7914478 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Stress response" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001633, CAB004262, HPA064711" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Golgi apparatus" "CAB004262: AB_627925, HPA001633: AB_1079516, HPA064711: AB_2685331" "unprognostic (1.77e-1)" "unprognostic (5.04e-2)" "unprognostic (1.06e-2)" "unprognostic (2.16e-1)" "unprognostic (4.24e-2)" "prognostic favorable (8.54e-5)" "unprognostic (1.80e-3)" "unprognostic (2.55e-1)" "unprognostic (2.69e-2)" "unprognostic (1.69e-2)" "unprognostic (1.27e-3)" "unprognostic (1.56e-1)" "unprognostic (3.54e-2)" "unprognostic (3.71e-2)" "unprognostic (6.05e-2)" "unprognostic (1.73e-2)" "prognostic favorable (1.56e-4)" 19.1 17.0 17.9 11.7 17.8 19.4 19.5 16.8 19.0 25.1 10.4 24.4 13.1 26.1 3.7 20.2 20.5 5.9 20.8 14.8 15.2 18.7 24.7 17.1 11.7 17.3 17.3 23.2 21.6 9.6 23.4 9.2 17.1 21.0 4.6 5.6 19.2 7.9 52.4 27.9 20.1 6.2 15.1 24.5 18.8 17.5 17.3 10.9 19.0 16.4 6.1 22.0 22.4 19.9 25.8 14.4 12.2 20.2 9.7 9.3 22.8 16.5 8.0 11.0 11.3 20.9 15.2 30.5 25.9 8.8 10.7 22.9 10.7 12.8 4.3 24.7 53.3 21.4 20.9 15.6 12.4 20.1 26.0 10.8 16.1 8.7 9.8 14.5 10.0 21.9 31.9 38.5 6.5 13.4 28.8 48.6 21.7 13.6 32.0 28.5 13.4 31.0 9.8 21.0 22.4 22.5 11.3 19.4 23.9 7.3 21.0 22.7 15.3 33.2 19.0 23.7 22.7 55.5 27.7 28.8 16.6 29.2 13.6 0.0 0.8 0.6 0.6 0.8 0.4 0.7 0.5 0.6 0.4 1.0 0.5 0.7 1.5 1.0 0.5 0.8 0.2 0.4 17.9 17.8 16.8 19.0 14.8 15.2 17.3 17.3 17.1 15.1 17.3 19.9 15.4 25.6 18.1 11.1 27.0 38.6 37.2 22.7 22.2 52.9 23.5 16.5 14.4 24.3 14.5 20.2 77.2 28.3 27.8 31.1 13.7 22.8 4.8 16.2 20.3 19.5 36.5 23.6 9.9 19.0 31.1 18.5 16.3 24.8 10.8 33.3 21.4 22.2 18.6 57.2 11.0 24.0 32.6 22.2 17.1 11.7 28.9 20.5 32.0 6.5 25.3 23.9 46.4 9.0 15.0 25.7 20.8 12.4 30.4 39.8 38.7 18.4 15.3 65.7 32.9 30.2 22.1 17.7 36.4 22.7 42.6 49.3 30.3 30.3 27.6 33.2 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 85.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 55.9;HHSteC: 53.7;HSkMC: 51.8;hTERT-RPE1: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 12.6 7.6 12.9 5.4 15.2 3.2 10.3 25.9 19.6 23.5 4.3 13.3 3.2 22.9 4.8 4.0 18.5 14.0 8.6 15.6 11.3 8.5 1.7 11.2 4.4 11.9 11.1 21.6 3.6 7.3 22.7 6.4 13.2 9.6 3.8 13.6 4.9 10.9 2.7 5.7 8.9 14.4 8.0 9.0 7.3 9.0 13.0 6.0 8.6 6.3 2.7 14.0 12.2 13.7 0.5 15.1 8.6 14.2 55.9 28.9 1.2 10.1 18.9 10.8 11.0 0.3 1.8 3.5 5.4 10.8 8.7 0.1 4.3 6.8 4.3 4.9 5.4 3.5 8.3 0.0 53.7 0.1 3.6 51.8 5.2 14.6 7.8 69.1 16.9 7.8 0.1 15.7 10.0 6.7 3.8 0.9 3.2 0.0 5.5 5.4 6.3 1.0 5.4 0.1 9.3 12.4 5.6 6.8 14.9 1.8 4.6 10.3 12.9 10.2 10.8 4.5 2.5 6.1 8.0 0.0 16.8 6.9 10.4 0.0 0.5 0.0 0.4 0.4 0.8 0.1 0.5 0.6 0.2 0.0 0.2 0.3 1.0 0.2 0.1 0.0 0.1 0.1 12.9 15.2 25.9 19.6 15.6 11.3 11.9 11.1 13.2 8.0 13.0 13.7 11.4 6.4 14.6 21.5 8.1 0.8 2.4 0.5 4.6 28.9 5.6 5.2 0.8 7.2 6.4 1.8 37.5 1.9 12.2 4.8 9.8 6.7 1.5 11.5 27.6 10.4 3.5 1.3 21.1 1.8 2.2 11.0 2.0 15.8 12.7 7.0 15.0 7.8 4.1 30.3 19.1 2.8 2.0 10.3 2.2 1.8 8.1 8.6 0.0 8.4 8.5 19.9 5.2 10.6 11.0 4.4 2.1 8.2 6.7 5.3 7.1 14.8 5.5 85.0 6.6 23.5 10.2 2.5 2.1 2.5 1.0 2.2 11.6 12.5 4.1 3.9 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327724-233385148 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 20.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 10.0;Collecting duct cells: 14.7;Ductal cells: 11.9;Exocrine glandular cells: 9.8;Glandular and luminal cells: 11.7;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.5" "Cell line enhanced" "Detected in many" "HEK 293: 27.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.7 3.8 1.8 1.3 1.6 2.1 2.5 5.2 2.4 1.0 0.7 6.3 11.7 1.2 3.3 2.5 4.6 1.7 0.4 1.4 1.4 13.5 5.4 4.5 0.9 1.5 0.3 0.7 20.3 4.3 2.1 0.3 1.7 1.3 6.9 1.0 3.8 2.7 0.0 3.3 10.1 0.6 0.2 0.5 12.4 9.4 1.8 0.4 2.3 0.0 1.3 1.2 1.8 1.3 11.6 19.4 0.4 0.0 0.0 0.0 9.6 0.3 0.0 0.4 0.8 10.8 9.8 1.1 7.7 0.2 3.6 6.0 14.4 5.9 1.2 21.6 27.4 0.1 11.4 0.0 0.7 19.0 4.3 0.2 7.8 0.3 10.9 2.2 0.7 8.7 0.2 3.7 0.0 2.6 6.1 6.8 13.6 13.4 8.4 0.0 0.0 20.7 13.1 4.8 13.9 3.7 6.6 0.3 0.0 1.5 5.6 6.0 0.0 0.0 1.8 0.1 11.5 3.4 4.6 0.0 1.8 5.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.8 1.6 5.2 2.4 1.4 1.4 1.5 0.3 1.7 0.2 1.8 1.3 0.9 35.3 10.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 6.5 0.0 0.0 0.6 14.7 0.0 0.0 0.4 0.0 3.9 11.9 0.0 5.7 1.0 0.3 0.0 0.0 0.0 9.8 0.0 0.5 0.0 11.7 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.7 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 MAP3K6 "ASK2, MAPKKK6, MEKK6" ENSG00000142733 "Mitogen-activated protein kinase kinase kinase 6" O95382 1 27354067-27366961 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 45.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" HPA051192 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane, Actin filaments, Cytosol" "HPA051192: AB_2681380" "unprognostic (1.19e-2)" "unprognostic (2.77e-3)" "unprognostic (2.62e-2)" "unprognostic (1.97e-2)" "prognostic unfavorable (2.13e-4)" "prognostic favorable (7.26e-4)" "prognostic unfavorable (8.76e-4)" "unprognostic (9.10e-2)" "unprognostic (2.79e-1)" "unprognostic (6.91e-2)" "unprognostic (6.56e-2)" "unprognostic (1.25e-1)" "unprognostic (4.65e-3)" "unprognostic (4.95e-2)" "unprognostic (2.79e-1)" "unprognostic (7.07e-3)" "unprognostic (1.50e-1)" 42.9 17.8 17.2 5.5 17.0 0.6 42.6 17.4 20.7 50.2 16.8 25.4 1.8 30.9 4.1 70.0 38.8 4.7 61.8 16.6 17.4 37.3 10.4 54.2 4.7 18.4 17.5 15.6 15.2 5.2 18.0 5.1 17.6 41.3 4.5 1.4 30.3 7.3 15.2 65.7 17.7 12.1 17.3 22.3 23.6 8.3 18.4 2.8 30.3 11.3 7.9 39.8 53.4 16.6 7.2 7.2 6.9 4.4 9.9 12.5 1.4 9.0 5.3 7.2 4.4 2.0 9.4 0.1 8.4 16.4 3.2 10.1 2.0 6.4 3.6 6.5 7.1 0.3 16.0 4.7 2.7 0.5 0.4 10.2 17.6 7.8 2.3 8.8 4.0 0.7 2.0 2.7 10.2 25.1 0.2 9.0 2.2 8.7 8.1 2.3 3.2 1.7 12.9 9.1 2.0 3.0 8.5 7.1 6.3 3.1 4.4 5.0 11.6 13.2 7.2 16.6 5.2 3.5 4.1 0.0 12.1 5.8 4.3 0.9 0.6 3.3 2.8 2.0 3.7 1.5 2.5 3.1 1.3 2.0 1.8 1.6 1.2 0.7 4.5 0.0 3.0 1.2 17.2 17.0 17.4 20.7 16.6 17.4 18.4 17.5 17.6 17.3 18.4 16.6 45.8 19.2 17.8 6.2 3.9 12.5 11.9 8.8 17.1 1.1 8.1 8.9 12.2 5.7 10.3 3.7 0.0 1.2 4.3 8.4 3.9 2.8 0.4 2.3 6.0 27.7 0.0 0.8 1.5 4.4 2.5 10.3 8.6 5.2 2.5 1.2 28.9 0.9 2.8 5.0 1.7 6.1 4.1 8.5 7.1 1.2 16.1 6.4 5.4 5.6 9.3 5.4 8.2 0.0 0.2 12.8 1.9 15.1 3.1 9.5 1.1 1.7 6.2 0.8 6.6 10.8 11.1 13.5 7.7 14.7 14.8 0.1 8.2 0.3 8.8 14.9 MAP3K7 "MEKK7, TAK1" ENSG00000135341 "Mitogen-activated protein kinase kinase kinase 7" O43318 6 90513573-90587072 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Stress response, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 137.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007633, HPA075335" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nuclear speckles, Plasma membrane" "HPA007633: AB_1079359, HPA075335: " "unprognostic (1.48e-1)" "unprognostic (3.45e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (1.44e-1)" "unprognostic (1.84e-1)" "prognostic unfavorable (3.51e-4)" "unprognostic (9.77e-2)" "unprognostic (6.51e-2)" "unprognostic (1.98e-2)" "unprognostic (1.44e-1)" "unprognostic (2.79e-1)" "unprognostic (2.56e-3)" "unprognostic (4.76e-2)" "unprognostic (1.95e-1)" "unprognostic (2.08e-1)" "unprognostic (1.17e-1)" 11.8 12.5 13.1 12.5 15.1 8.7 14.3 15.6 17.3 14.3 11.7 11.6 9.2 16.6 16.5 10.6 11.0 12.7 16.9 14.7 14.9 11.4 11.6 10.4 16.4 15.3 13.7 15.8 9.7 16.3 13.0 17.4 15.8 14.9 10.9 23.5 12.1 13.3 16.9 13.9 9.8 14.0 15.3 17.6 10.8 9.9 13.8 20.8 14.7 18.4 16.8 14.3 12.2 22.4 16.7 14.4 41.3 35.6 29.5 39.1 29.0 32.7 37.7 28.8 36.1 18.6 15.5 36.9 20.4 35.6 25.6 17.3 26.3 25.5 48.7 19.0 27.7 32.9 19.9 24.9 30.8 36.9 24.4 32.5 30.5 28.2 34.2 33.1 27.4 31.8 67.0 29.3 41.8 20.3 17.2 31.2 34.0 25.7 18.0 29.3 73.9 18.0 24.2 18.4 20.8 29.5 22.9 15.6 24.8 32.2 15.5 64.7 26.5 23.3 14.7 21.6 30.9 25.9 24.7 15.8 35.7 39.7 35.0 18.2 11.5 18.4 12.8 15.9 14.5 13.0 12.3 12.5 14.6 9.9 13.7 13.4 11.5 17.9 17.6 8.9 20.8 13.4 13.1 15.1 15.6 17.3 14.7 14.9 15.3 13.7 15.8 15.3 13.8 22.4 16.1 16.0 26.9 47.0 24.3 36.3 20.8 19.5 21.6 23.3 17.9 12.3 31.0 14.3 16.9 16.5 27.1 31.8 17.8 12.4 7.9 17.6 3.6 10.9 19.8 21.2 12.1 14.1 85.7 20.9 34.6 23.2 16.3 14.8 13.9 25.9 25.7 20.7 24.3 28.6 63.8 13.7 20.3 27.3 24.6 3.2 26.8 21.7 21.4 36.5 35.2 19.6 16.5 50.8 137.2 20.1 9.1 41.0 18.8 30.1 11.1 16.6 21.4 21.5 19.7 28.0 18.5 25.9 24.9 21.3 37.2 48.4 22.7 18.1 15.1 24.8 MAP4 ENSG00000047849 "Microtubule associated protein 4" P27816 3 47850690-48089272 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 743.9" "Cell type enhanced" "Detected in all" "Bipolar cells: 392.2;Cardiomyocytes: 921.5;Cone photoreceptor cells: 625.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038149, HPA038150" Enhanced Approved "Plasma membrane,Microtubules,Cytosol" NA NA 880000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Microtubules, Cytosol" "Plasma membrane" "HPA038149: AB_10672471, HPA038150: AB_10672505" "unprognostic (2.51e-1)" "unprognostic (4.48e-1)" "unprognostic (2.72e-1)" "unprognostic (1.95e-2)" "unprognostic (3.36e-1)" "unprognostic (4.57e-1)" "prognostic unfavorable (1.82e-4)" "unprognostic (6.82e-2)" "unprognostic (1.46e-2)" "unprognostic (5.02e-2)" "unprognostic (2.23e-2)" "unprognostic (1.30e-2)" "unprognostic (2.25e-2)" "unprognostic (8.89e-2)" "unprognostic (6.45e-2)" "unprognostic (1.88e-1)" "unprognostic (1.21e-3)" 127.4 55.7 475.5 50.4 483.4 16.1 98.0 433.2 406.8 118.0 215.5 193.2 35.1 111.7 69.7 90.7 94.7 52.9 380.9 351.2 408.7 88.3 66.0 105.0 35.0 567.9 490.6 90.0 71.4 31.4 56.1 64.8 509.2 92.7 47.6 149.0 71.4 88.1 743.9 120.6 80.6 94.5 526.1 64.0 93.9 80.0 552.3 42.1 61.1 491.0 37.8 135.5 115.2 533.2 121.9 95.7 117.1 89.3 168.6 298.5 49.5 222.6 241.2 184.1 204.9 81.3 74.4 102.3 50.7 337.9 172.8 79.2 151.4 201.6 204.7 148.7 63.8 69.3 102.8 106.0 228.6 48.6 53.9 251.4 246.4 224.0 271.6 167.1 245.1 70.6 91.2 115.3 146.9 69.1 69.5 58.9 70.9 59.9 195.0 36.6 110.1 128.1 118.2 100.1 46.4 72.3 171.0 68.3 118.6 163.0 50.1 44.8 334.5 172.7 132.3 182.9 144.4 80.4 66.9 47.8 222.2 58.6 167.3 10.5 6.6 3.7 15.6 10.6 7.5 12.3 10.2 12.7 7.1 11.5 4.9 7.6 2.6 13.4 27.3 10.8 13.0 9.7 475.5 483.4 433.2 406.8 351.2 408.7 567.9 490.6 509.2 526.1 552.3 533.2 147.9 70.5 48.2 124.4 45.1 74.8 55.4 53.1 42.7 392.2 34.7 36.2 921.5 48.6 53.4 80.9 625.5 33.8 54.6 43.7 27.4 97.8 116.2 78.2 143.2 110.4 28.8 21.6 63.7 65.3 81.0 105.5 39.8 93.4 27.8 81.6 50.0 57.3 38.0 47.1 71.2 31.7 34.6 28.3 50.5 38.8 77.0 40.0 78.2 95.5 72.0 82.8 47.4 77.9 167.2 92.0 28.0 103.0 47.2 89.0 37.1 39.2 43.6 97.5 72.3 149.0 119.0 65.6 64.3 58.7 69.6 22.4 60.5 137.4 39.5 44.7 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" Q9Y4K4 14 50418501-50561126 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 332.7;Oligodendrocytes: 707.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 66.7;eosinophil: 26.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 66.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036696, HPA078030" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA036696: AB_10672362, HPA078030: " "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-3)" "unprognostic (4.13e-2)" "unprognostic (6.31e-2)" "unprognostic (2.24e-2)" "unprognostic (1.53e-3)" "unprognostic (7.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (2.02e-2)" 20.5 12.8 16.2 13.2 31.1 22.1 22.2 20.7 21.5 30.6 3.9 20.8 13.1 33.4 12.9 20.5 19.0 21.5 10.9 18.3 23.9 11.9 10.0 17.1 12.4 28.4 22.0 32.4 14.2 14.8 11.8 19.8 24.8 17.9 16.6 18.6 18.0 21.1 12.3 28.5 14.7 24.7 17.6 15.7 16.8 7.9 23.8 11.6 17.0 14.2 13.2 20.2 23.8 58.1 51.7 15.2 36.5 31.5 33.0 34.5 35.6 59.2 53.0 39.4 34.9 19.3 35.2 35.3 34.3 54.6 20.9 36.1 34.3 31.9 59.7 29.4 24.8 21.7 27.1 17.5 27.9 19.6 33.0 25.2 25.7 34.8 36.1 63.0 52.6 31.7 20.8 22.5 58.6 19.4 26.6 18.7 17.7 16.6 29.5 31.8 55.4 13.5 39.2 39.5 11.7 26.5 33.5 23.0 23.4 29.3 25.8 14.7 53.8 50.9 35.7 35.2 28.2 16.3 18.0 23.6 19.2 13.5 37.2 66.7 2.8 26.3 6.7 3.3 3.8 6.1 4.2 5.9 3.0 9.7 4.4 4.6 1.0 10.1 2.2 4.9 1.0 1.9 16.2 31.1 20.7 21.5 18.3 23.9 28.4 22.0 24.8 17.6 23.8 58.1 40.5 41.7 20.8 135.2 29.9 70.0 42.9 21.4 56.3 56.7 32.6 26.5 10.5 30.0 27.4 27.6 47.9 11.4 30.6 27.5 19.6 29.5 3.7 25.7 52.2 40.4 23.4 46.7 144.2 20.9 19.5 50.1 43.8 49.1 29.8 37.8 38.6 9.0 8.1 33.7 144.1 16.4 8.2 12.3 24.8 3.7 42.6 25.1 23.2 101.2 18.3 19.5 18.6 332.7 707.2 25.9 20.2 51.1 27.0 57.4 10.9 12.0 25.6 33.1 13.1 49.7 41.7 10.6 14.1 54.9 86.1 6.6 31.5 22.4 18.6 61.7 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MAPK15 "ERK7, ERK8" ENSG00000181085 "Mitogen-activated protein kinase 15" Q8TD08 8 143716340-143722458 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 54.9;fallopian tube: 46.7" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 62.5;Respiratory ciliated cells: 107.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 18.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 9.6;HeLa: 20.7;MCF7: 14.3;T-47d: 14.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA002704 Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA002704: AB_1079307" "unprognostic (9.11e-2)" "unprognostic (1.38e-1)" "unprognostic (8.04e-3)" "unprognostic (2.94e-1)" "unprognostic (2.54e-2)" "unprognostic (1.14e-2)" "unprognostic (1.22e-1)" "unprognostic (6.09e-2)" "unprognostic (2.59e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-1)" "unprognostic (9.51e-2)" "unprognostic (2.64e-2)" "unprognostic (1.54e-2)" "unprognostic (5.78e-1)" "unprognostic (6.35e-2)" "unprognostic (1.62e-2)" 1.6 0.1 3.3 0.2 4.0 0.0 1.9 1.7 8.1 6.9 54.9 1.0 0.3 2.5 2.4 1.1 46.7 0.2 0.6 5.0 3.6 10.5 0.3 12.1 0.4 10.2 14.5 0.9 4.4 9.4 6.9 0.3 7.0 2.2 0.2 0.0 2.2 1.7 0.1 4.0 0.8 0.4 6.6 0.7 0.8 11.4 6.4 1.1 16.1 0.0 0.2 0.5 2.1 3.0 0.4 0.6 1.9 0.0 0.0 0.0 0.7 1.8 0.0 0.0 0.0 0.5 9.6 0.0 1.6 0.0 0.0 5.5 0.1 0.2 0.0 1.0 2.0 0.0 20.7 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.2 0.0 0.2 3.4 0.0 0.0 14.3 0.0 0.0 2.5 1.2 1.2 0.0 3.7 0.5 1.0 1.6 3.6 5.1 0.0 3.3 0.0 0.2 14.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 4.0 1.7 8.1 5.0 3.6 10.2 14.5 7.0 6.6 6.4 3.0 0.1 0.0 6.4 0.0 0.1 0.4 0.3 5.7 0.0 0.0 1.0 1.3 0.7 0.0 11.8 0.0 0.0 0.0 0.0 0.1 0.0 1.1 13.8 62.5 0.5 0.3 0.0 0.0 0.2 0.0 0.7 0.8 0.0 1.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.6 16.2 0.0 0.0 11.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.3 0.0 1.4 107.9 0.0 0.0 0.4 2.2 2.3 0.9 0.0 0.3 0.1 0.2 0.1 0.3 0.1 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MAPK9 "JNK2, p54a, PRKM9, SAPK" ENSG00000050748 "Mitogen-activated protein kinase 9" P45984 5 180233143-180292099 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Biological rhythms" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 64.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "basophil: 16.3" "Lineage enriched" "Detected in all" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in all" "HDLM-2: 211.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008910, HPA072462" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nuclear speckles" "CAB008910: , HPA072462: " "unprognostic (5.04e-3)" "unprognostic (2.06e-2)" "prognostic favorable (1.11e-4)" "unprognostic (8.53e-2)" "unprognostic (1.75e-1)" "unprognostic (5.06e-3)" "unprognostic (6.83e-3)" "unprognostic (3.16e-1)" "unprognostic (4.93e-2)" "unprognostic (3.76e-1)" "unprognostic (5.97e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "unprognostic (2.13e-1)" "unprognostic (2.29e-1)" "unprognostic (9.38e-3)" "unprognostic (2.40e-1)" 19.3 21.1 28.4 18.4 32.6 21.3 17.5 36.5 41.4 17.7 7.2 22.4 18.5 15.3 16.2 15.4 15.3 13.9 25.7 34.2 25.8 21.1 17.7 19.5 19.9 25.7 19.7 14.6 45.7 30.1 12.9 19.7 26.4 20.0 26.4 21.4 19.1 21.6 40.8 11.7 19.3 19.9 16.9 16.6 22.5 17.8 22.2 22.5 26.7 34.8 21.1 17.4 11.1 29.8 52.7 42.7 37.0 46.5 35.7 39.3 79.4 49.6 43.5 40.5 40.5 56.4 36.7 55.9 83.1 52.6 89.3 39.6 38.4 82.8 47.5 211.8 36.9 23.2 46.8 40.3 27.1 49.0 39.2 29.3 36.5 39.5 38.0 42.5 48.9 43.0 26.2 39.5 55.9 68.9 49.2 20.4 25.8 64.8 25.0 46.9 62.7 26.9 30.8 49.7 42.5 29.9 58.2 55.8 40.4 45.8 56.9 41.7 35.5 48.3 49.2 69.3 75.2 28.2 35.6 37.9 51.5 44.8 32.9 16.3 0.5 2.2 1.6 1.1 1.6 0.8 1.2 1.4 0.8 1.3 0.8 0.9 0.7 1.2 2.3 1.2 2.7 0.3 28.4 32.6 36.5 41.4 34.2 25.8 25.7 19.7 26.4 16.9 22.2 29.8 20.5 32.1 14.4 26.1 10.5 10.1 7.0 6.5 9.1 21.9 16.8 12.2 27.6 12.8 8.5 9.2 16.7 15.3 20.5 20.7 5.9 8.0 1.2 17.6 14.2 12.2 16.7 9.5 62.5 16.0 23.3 11.1 15.8 18.6 11.4 14.5 12.5 16.7 11.7 13.5 64.3 17.9 4.1 24.2 20.5 3.1 10.5 15.0 5.4 31.9 13.9 11.4 15.5 25.1 32.9 13.1 12.3 13.5 15.6 10.2 13.4 11.0 6.9 14.8 13.1 13.5 13.7 17.0 17.1 9.4 11.4 17.8 14.7 8.2 15.4 8.8 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MARCHF10 "FLJ35757, MARCH-X, MARCH10, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 137.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.5;EFO-21: 4.7;HSkMC: 2.1;SCLC-21H: 8.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.1 0.2 1.3 0.2 1.6 0.0 0.1 1.2 0.9 1.4 10.5 1.1 0.0 0.4 7.5 0.1 12.8 0.1 0.1 1.1 1.3 1.5 0.0 2.7 0.0 3.6 5.0 0.1 0.2 0.3 12.7 0.0 2.6 0.6 0.0 0.1 0.3 0.1 0.0 0.2 0.4 0.0 3.6 0.1 0.4 137.6 1.3 0.2 0.1 0.0 0.0 0.1 0.2 2.0 0.1 0.0 0.1 0.0 0.0 0.1 2.5 1.1 0.1 0.8 0.2 0.0 0.0 0.0 4.7 0.3 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.8 0.6 0.0 1.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.7 0.0 8.3 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.2 0.1 1.3 1.6 1.2 0.9 1.1 1.3 3.6 5.0 2.6 3.6 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 33.3;Cardiomyocytes: 88.4;Cytotrophoblasts: 36.2;dendritic cells: 28.2;Extravillous trophoblasts: 38.8;Hofbauer cells: 34.0;Syncytiotrophoblasts: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 38.3 30.0 16.4 37.9 21.7 43.2 48.2 32.3 21.5 38.6 25.1 33.2 30.0 45.0 34.2 67.3 37.5 38.1 48.9 15.8 16.1 32.8 40.1 38.2 47.9 17.4 17.1 47.5 22.3 36.6 22.7 46.9 17.7 38.1 36.9 37.9 26.9 36.3 55.2 38.6 30.0 50.6 14.9 45.1 33.5 62.0 17.1 60.8 47.5 44.1 52.2 39.0 37.5 21.8 50.3 35.3 88.7 40.7 61.9 81.9 89.1 83.9 81.1 82.5 73.9 70.9 57.5 71.0 36.8 84.2 46.8 61.3 55.4 74.5 102.9 75.9 43.2 96.0 53.8 53.3 60.7 79.9 72.6 72.7 83.0 99.5 86.5 92.5 99.3 50.7 75.6 65.6 82.9 44.2 52.4 73.8 84.6 54.6 47.3 75.0 64.5 59.3 74.6 112.1 51.9 48.6 65.6 48.2 67.0 94.3 56.9 94.4 93.5 86.9 51.9 53.9 47.2 51.5 61.0 96.8 54.1 46.8 84.0 83.5 28.8 59.6 28.6 29.5 33.3 27.6 30.4 32.4 27.6 26.4 36.3 35.9 127.5 39.4 43.4 22.3 34.3 30.9 16.4 21.7 32.3 21.5 15.8 16.1 17.4 17.1 17.7 14.9 17.1 21.8 33.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 36.2 28.2 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 38.8 13.5 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 44.2 5.8 0.0 0.0 0.0 MARCKS "80K-L, MACS, PKCSL" ENSG00000277443 "Myristoylated alanine rich protein kinase C substrate" P29966 6 113857345-113863475 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 12.7;neutrophil: 18.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 405.8;TIME: 326.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022062, HPA054820, HPA067595, HPA069443" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA 19000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Endoplasmic reticulum, Cytosol" "CAB022062: AB_309681, HPA054820: AB_2682613, HPA067595: AB_2732772, HPA069443: AB_2732133" "unprognostic (4.71e-1)" "unprognostic (1.91e-2)" "unprognostic (2.46e-1)" "unprognostic (5.51e-3)" "unprognostic (8.22e-3)" "unprognostic (2.38e-2)" "prognostic unfavorable (2.78e-8)" "unprognostic (7.82e-2)" "unprognostic (2.57e-1)" "unprognostic (6.92e-2)" "unprognostic (2.27e-1)" "unprognostic (3.56e-2)" "prognostic unfavorable (4.85e-4)" "unprognostic (1.36e-3)" "unprognostic (2.77e-2)" "unprognostic (8.07e-2)" "unprognostic (2.70e-2)" 42.8 16.8 65.1 58.2 64.1 104.6 50.2 73.2 78.5 31.9 21.6 75.7 38.9 31.2 13.5 45.1 27.3 35.8 18.2 56.8 89.2 24.6 26.1 35.0 45.4 81.0 87.6 39.0 42.4 7.0 20.6 63.0 73.1 37.8 68.2 22.0 28.0 18.0 15.7 32.1 43.3 30.1 106.8 57.0 62.8 10.3 85.5 44.8 16.2 12.9 45.3 86.2 34.5 102.8 39.2 22.6 405.8 22.3 134.0 86.6 2.2 123.0 171.4 84.9 140.6 40.7 54.1 0.1 25.3 228.0 67.3 118.0 67.9 35.7 109.7 0.3 40.2 0.0 22.2 53.3 89.2 10.3 0.7 90.2 68.8 81.8 77.4 231.9 243.1 0.4 4.6 107.6 122.1 0.4 1.3 0.3 52.7 43.5 29.4 0.2 40.7 4.1 26.9 73.6 56.4 163.4 78.7 39.6 89.6 95.0 2.1 11.3 326.0 78.3 0.5 129.9 212.7 288.3 22.4 11.4 60.2 55.8 153.4 0.0 3.9 0.0 0.0 12.7 0.0 4.6 0.0 0.0 1.1 1.9 0.0 0.0 18.7 0.0 7.5 0.0 0.0 0.5 65.1 64.1 73.2 78.5 56.8 89.2 81.0 87.6 73.1 106.8 85.5 102.8 211.2 9.6 15.5 44.7 139.0 504.1 540.7 232.3 275.4 157.0 213.2 176.7 16.6 57.2 115.0 38.6 29.2 7.2 5.5 629.5 37.2 144.3 55.7 111.2 444.0 271.6 336.3 2.5 33.0 229.9 11.2 372.6 135.1 130.4 2.5 526.1 236.0 8.8 371.6 84.1 21.0 369.4 126.1 286.3 605.5 35.7 120.5 381.3 273.9 60.0 447.2 315.5 2.1 194.5 9.7 208.1 223.1 67.0 105.2 380.1 89.9 6.9 145.0 37.7 39.5 89.8 222.8 22.7 16.2 326.3 638.5 29.4 22.3 62.3 352.3 620.2 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MARVELD2 "DFNB49, FLJ30532, MRVLDC2, TRIC" ENSG00000152939 "MARVEL domain containing 2" Q8N4S9 5 69415065-69444330 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 15.7" "Cell type enhanced" "Detected in many" "Urothelial cells: 46.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 29.5;CAPAN-2: 24.1;HaCaT: 18.9;RT4: 21.1;SCLC-21H: 26.7;T-47d: 18.3" "Region enriched" "Detected in some" 8 "cerebellum: 7.9" "Low region specificity" "Detected in all" "HPA018119, HPA061726" Uncertain Supported "Cell Junctions" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA018119: AB_2669771, HPA061726: AB_2684595" "unprognostic (4.11e-2)" "unprognostic (3.05e-1)" "unprognostic (1.22e-2)" "unprognostic (2.44e-3)" "unprognostic (1.68e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" "unprognostic (8.84e-2)" "unprognostic (2.43e-1)" "unprognostic (3.47e-2)" "unprognostic (2.60e-2)" "unprognostic (1.75e-1)" "prognostic favorable (2.84e-13)" "unprognostic (1.78e-1)" "unprognostic (1.19e-1)" "unprognostic (3.67e-2)" "unprognostic (1.82e-1)" 0.3 0.2 0.5 0.9 0.5 0.2 4.0 0.5 0.6 2.1 3.2 5.7 7.7 1.1 1.3 6.9 3.9 2.9 0.4 0.5 0.5 8.0 10.7 5.6 0.1 0.7 0.7 0.1 9.3 4.6 2.9 1.8 0.7 3.0 6.2 0.3 4.6 2.6 0.0 4.3 7.7 0.4 0.4 0.2 8.1 1.5 0.7 1.0 15.7 0.0 1.3 3.0 3.4 0.7 10.8 3.5 0.1 0.0 0.0 0.0 29.5 0.2 0.2 0.2 0.7 14.1 24.1 0.1 2.0 1.8 0.0 18.9 0.0 14.0 0.5 0.2 5.8 0.0 1.1 7.8 1.7 0.0 0.1 0.4 15.3 0.1 1.9 0.7 0.9 0.1 0.0 0.1 0.0 9.8 0.0 0.0 1.8 6.3 0.3 0.0 0.1 0.5 10.0 21.1 26.7 0.0 2.3 2.0 0.3 4.3 18.3 0.0 1.5 0.0 0.1 0.0 0.0 0.1 3.5 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.5 0.5 0.5 0.6 0.5 0.5 0.7 0.7 0.7 0.4 0.7 0.7 1.0 22.4 26.5 0.7 1.0 5.0 22.2 14.8 10.2 0.3 15.5 8.5 2.8 35.8 23.1 16.5 2.1 22.9 0.2 31.4 17.6 25.1 5.8 33.5 3.4 4.1 16.8 3.4 0.5 25.8 8.2 1.1 17.9 30.4 1.3 3.7 5.0 37.9 1.9 0.0 0.4 23.1 18.3 0.6 0.9 3.2 0.0 0.6 1.8 1.0 7.8 0.5 0.0 0.5 0.6 25.0 29.7 0.0 0.6 25.5 33.5 6.1 38.4 0.6 0.0 0.8 1.5 4.1 2.4 19.4 6.5 12.0 0.9 2.9 25.6 46.9 MAS1L "dJ994E9.2, MAS-L, MRG" ENSG00000204687 "MAS1 proto-oncogene like, G protein-coupled receptor" P35410 6 29486697-29487956 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "cervix: 3.1;epididymis: 1.9" "Cell type enriched" "Detected in single" 62 "granulocytes: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA017983 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA017983: AB_1849332" "unprognostic (3.66e-2)" "unprognostic (2.51e-1)" "unprognostic (2.30e-2)" "unprognostic (5.22e-2)" "unprognostic (1.65e-1)" 0.4 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 3.1 0.0 0.7 0.3 0.7 1.9 1.1 0.2 0.7 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.3 0.2 0.0 0.3 0.7 0.6 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.6 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MAT2B "MATIIbeta, SDR23E1" ENSG00000038274 "Methionine adenosyltransferase 2B" Q9NZL9 5 163503114-163519354 "Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037721, HPA037722" Uncertain Approved "Plasma membrane" NA NA 1100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA037721: AB_10672389, HPA037722: AB_10671718" "unprognostic (1.22e-2)" "unprognostic (2.80e-2)" "unprognostic (1.80e-3)" "unprognostic (1.64e-1)" "unprognostic (5.06e-1)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (9.72e-2)" "unprognostic (1.68e-1)" "unprognostic (5.19e-3)" "unprognostic (3.57e-2)" "prognostic favorable (4.51e-7)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-3)" 36.6 54.6 31.1 64.7 32.4 31.1 50.5 35.3 39.8 46.9 37.5 61.5 86.9 45.4 59.4 40.9 66.7 42.1 75.3 32.8 33.7 104.8 82.7 56.1 102.6 32.2 35.3 73.3 23.9 69.2 22.0 48.9 33.3 46.1 66.5 47.8 64.3 53.2 57.8 34.6 84.4 44.4 34.6 84.5 57.2 31.7 33.3 89.6 81.4 63.7 92.7 60.9 33.2 34.0 72.4 60.0 100.6 55.1 73.4 72.9 62.2 61.8 68.5 67.7 99.4 41.5 128.5 74.8 127.6 66.0 99.5 56.6 84.8 125.4 89.1 254.5 69.6 67.3 63.3 62.1 95.9 71.0 44.7 60.4 101.1 86.1 66.4 81.8 149.5 76.6 54.8 90.8 84.0 40.7 99.2 85.9 38.6 43.9 40.0 112.4 49.2 123.4 111.7 76.6 40.4 57.9 82.8 58.2 93.8 44.1 76.5 95.1 121.2 73.6 48.5 51.8 107.7 78.4 82.3 68.3 54.1 129.1 51.3 619.4 227.5 477.4 321.5 274.3 355.8 359.1 351.2 349.3 204.6 345.3 352.7 341.4 357.8 401.5 302.4 167.2 528.3 689.9 31.1 32.4 35.3 39.8 32.8 33.7 32.2 35.3 33.3 34.6 33.3 34.0 24.9 48.1 43.3 8.8 90.1 42.7 35.1 75.6 129.1 23.2 26.0 20.7 57.7 41.5 48.1 44.1 8.4 61.3 62.8 49.2 62.6 38.8 39.0 63.5 36.2 38.9 15.0 79.3 15.0 26.2 29.7 34.6 36.2 44.2 28.4 28.1 35.7 58.3 45.3 18.5 12.8 40.8 61.1 83.3 55.3 13.3 34.5 48.5 42.7 18.7 70.6 41.7 80.3 9.0 16.2 28.9 38.1 31.2 65.7 46.8 53.4 103.7 72.6 17.6 46.0 21.7 35.6 23.6 30.5 69.8 36.2 37.6 84.2 23.3 51.3 45.7 MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 11 "Oligodendrocytes: 2895.5" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 99.3;SK-MEL-30: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" 27.3 7.1 15448.6 20.9 21296.6 43.0 20.9 19749.8 26916.8 17.3 9144.9 19.0 18.6 13.2 7.9 20.5 31.5 17.2 24.1 12696.6 16271.8 28.7 23.5 20.0 26.9 30812.9 22193.8 22.3 22.8 47.5 26.7 4.7 25986.2 15.3 16.9 7.5 22.0 13.0 140.8 28.7 20.7 8.7 23219.4 28.0 17.5 6.1 19406.0 12.5 22.2 81.6 27.8 19.0 20.2 30044.2 26.1 22.4 0.2 0.8 35.8 53.1 8.5 0.6 0.6 0.8 0.6 3.2 39.2 15.9 4.4 1.7 0.2 49.9 3.8 22.1 0.7 60.7 5.3 10.4 3.9 5.2 22.5 99.3 65.3 7.7 18.4 19.8 30.3 16.4 6.5 37.9 0.0 3.6 0.0 3.2 4.1 50.6 2.2 15.6 18.1 1.5 0.4 35.9 34.5 34.3 1.8 0.3 3.2 0.0 204.7 6.1 0.6 60.5 0.1 0.2 0.5 0.2 2.8 0.1 0.5 16.9 5.8 62.0 2.5 21.7 8.5 32.4 21.6 8.1 13.1 5.9 15.4 28.1 9.2 5.1 9.1 17.0 39.5 28.0 8.1 11.9 14.9 11.6 15448.6 21296.6 19749.8 26916.8 12696.6 16271.8 30812.9 22193.8 25986.2 23219.4 19406.0 30044.2 5.5 48.1 39.5 10.7 86.8 118.8 61.1 28.1 84.2 52.8 24.2 22.7 45.0 35.8 50.3 103.0 2.1 0.7 221.8 48.7 41.1 43.7 5.9 159.8 11.2 9.4 49.8 68.8 32.4 35.8 0.8 36.2 59.1 161.1 71.5 2.1 10.0 30.2 44.4 1.7 47.1 51.4 44.7 78.3 123.1 6.3 28.3 98.2 92.5 45.0 84.4 25.7 247.2 124.7 2895.5 60.4 25.5 14.3 45.3 117.6 37.5 36.0 54.0 6.1 0.0 88.7 8.4 7.7 1.1 75.6 154.7 0.7 151.6 0.0 42.1 103.7 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MCMBP "C10orf119, FLJ13081, MCM-BP" ENSG00000197771 "Minichromosome maintenance complex binding protein" Q9BTE3 10 119829404-119892556 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013792, HPA038481" Uncertain Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "CAB013792: , HPA038481: AB_10794620" "unprognostic (1.26e-1)" "unprognostic (7.92e-2)" "unprognostic (4.62e-2)" "unprognostic (2.31e-2)" "unprognostic (1.72e-2)" "unprognostic (4.64e-2)" "unprognostic (1.31e-3)" "unprognostic (5.61e-2)" "unprognostic (2.28e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (2.20e-4)" "unprognostic (7.32e-2)" "prognostic unfavorable (6.18e-4)" "unprognostic (2.23e-2)" "unprognostic (8.24e-2)" "unprognostic (2.51e-1)" "unprognostic (4.87e-2)" 30.5 14.2 9.1 16.7 10.5 10.0 26.1 12.9 11.9 23.8 9.7 25.9 13.3 26.7 10.8 25.0 23.7 12.1 18.2 9.4 10.4 16.1 18.6 24.9 18.9 11.3 10.2 22.2 17.0 16.1 11.0 25.3 11.5 15.2 16.6 12.3 20.5 13.7 30.1 25.6 19.6 18.3 11.5 19.5 20.3 11.8 9.9 20.7 17.5 15.9 19.7 25.1 24.1 12.4 54.4 28.6 49.6 40.3 24.0 27.1 27.0 49.2 55.9 62.2 63.3 42.5 32.9 69.7 20.3 34.8 20.7 46.8 65.1 46.8 74.1 46.0 50.3 34.7 20.8 38.3 35.7 71.3 80.6 24.1 25.8 47.4 60.7 27.6 38.9 37.5 35.3 43.9 41.7 28.5 77.4 52.6 33.3 34.7 26.5 49.8 104.0 30.8 29.0 30.0 25.0 28.7 32.9 33.1 39.3 33.0 20.4 50.2 34.3 26.5 24.1 29.8 56.3 36.1 37.7 71.1 35.5 46.1 16.2 9.8 2.3 1.4 2.0 4.2 2.0 2.0 2.0 1.9 3.2 0.9 2.0 2.2 3.0 1.8 2.5 1.5 1.9 1.1 9.1 10.5 12.9 11.9 9.4 10.4 11.3 10.2 11.5 11.5 9.9 12.4 39.0 16.0 16.5 11.8 26.2 42.8 35.0 12.3 24.5 11.4 18.1 14.2 18.6 25.8 15.6 20.2 4.2 40.5 35.4 23.7 13.7 11.7 4.6 18.8 31.7 38.3 10.8 25.0 14.0 13.7 52.6 27.4 12.2 26.2 18.3 18.2 26.7 25.6 38.5 32.0 17.3 20.8 12.2 35.5 35.0 6.2 30.1 35.9 23.2 15.0 34.2 18.3 26.8 17.6 25.3 15.8 11.9 22.6 28.0 32.8 15.6 18.7 12.5 18.3 19.7 32.8 27.4 42.5 68.7 29.9 42.8 39.7 31.6 12.7 29.1 29.1 MCTS1 MCT-1 ENSG00000232119 "MCTS1 re-initiation and release factor" Q9ULC4 X 120594010-120621159 "Predicted intracellular proteins" "Cell cycle, DNA damage, Growth regulation, Protein biosynthesis, Transcription, Transcription regulation" "Initiation factor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001045 Supported "Plasma membrane,Cytosol" NA NA 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "HPA001045: " "prognostic unfavorable (1.38e-4)" "unprognostic (1.44e-1)" "unprognostic (4.50e-1)" "unprognostic (9.37e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (3.27e-5)" "unprognostic (2.94e-3)" "unprognostic (9.59e-2)" "unprognostic (8.28e-2)" "unprognostic (4.89e-2)" "unprognostic (7.42e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (1.95e-1)" "unprognostic (7.58e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" 28.1 31.1 5.5 3.9 5.6 3.9 26.4 5.7 7.0 24.5 4.3 25.9 4.6 19.7 6.3 38.9 19.3 3.0 32.9 6.0 6.0 35.9 40.7 20.8 5.5 5.2 5.0 17.0 39.5 4.9 34.3 3.9 5.2 20.4 5.2 5.5 26.8 3.7 28.5 24.1 23.9 3.1 5.0 28.9 30.5 11.9 5.4 6.7 21.5 6.4 6.7 22.6 24.4 5.7 13.9 8.2 8.2 9.9 16.2 19.2 9.9 13.8 11.9 15.2 17.0 6.6 15.8 18.6 14.3 18.3 23.6 9.6 18.0 17.7 23.4 9.7 8.5 6.3 11.3 6.4 15.6 13.6 10.3 14.1 14.2 14.9 14.2 12.6 19.5 11.0 14.5 10.8 21.9 13.5 11.3 17.5 10.3 27.9 15.7 10.5 7.6 19.2 17.7 6.4 11.0 10.0 8.5 15.2 9.0 10.1 9.1 10.6 16.5 13.3 6.4 14.3 20.7 7.5 12.5 22.2 14.3 18.8 12.9 3.4 5.0 3.5 3.5 5.9 5.6 6.1 4.6 4.4 6.5 4.9 4.2 4.3 2.3 4.9 5.9 8.4 6.1 4.1 5.5 5.6 5.7 7.0 6.0 6.0 5.2 5.0 5.2 5.0 5.4 5.7 53.5 19.2 22.9 13.1 65.4 32.2 65.5 108.4 27.9 14.5 49.3 46.9 80.8 42.9 63.5 46.0 8.4 97.0 52.0 71.3 129.1 87.4 54.4 53.1 55.6 49.9 55.7 22.5 28.2 88.5 182.0 48.5 50.0 43.9 52.0 50.4 51.4 84.4 132.6 15.2 25.5 111.0 71.2 81.7 43.2 88.7 42.0 60.4 62.2 10.3 67.6 27.0 39.1 15.1 25.3 92.7 83.7 27.8 92.0 52.6 118.2 153.5 57.4 21.0 39.5 25.3 66.1 17.7 15.0 50.4 34.5 112.9 46.5 90.0 82.2 75.3 MCTS2P "MCTS2, psiMCT-1" ENSG00000101898 "MCTS family member 2, pseudogene" 20 31547412-31548081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA001045 Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA001045: " "unprognostic (1.71e-2)" "unprognostic (2.07e-2)" "unprognostic (6.17e-3)" "unprognostic (6.04e-3)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (8.10e-2)" "unprognostic (2.97e-2)" "unprognostic (1.52e-1)" "unprognostic (5.49e-2)" "unprognostic (1.41e-1)" "unprognostic (9.81e-2)" "unprognostic (3.90e-4)" "unprognostic (6.59e-2)" "unprognostic (9.97e-2)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" 0.9 0.6 0.2 1.6 0.3 1.5 2.2 0.7 1.3 1.0 0.3 1.6 1.0 1.0 0.5 1.3 1.4 0.6 0.6 0.3 0.4 1.0 0.7 0.8 1.8 0.2 0.5 2.5 0.7 1.7 1.5 0.4 1.2 1.1 1.4 0.8 0.9 0.6 0.6 0.5 1.4 0.1 0.8 1.3 1.3 0.4 2.3 1.6 0.7 2.7 2.1 0.4 8.8 0.0 7.6 7.2 2.2 5.4 0.0 3.2 5.1 10.3 4.3 0.2 4.1 13.3 0.1 4.4 3.8 11.1 0.1 15.0 12.4 0.2 10.1 20.2 2.4 2.3 3.1 17.4 10.7 3.8 7.2 4.1 7.4 3.3 4.2 8.0 9.7 4.6 3.8 3.2 16.0 2.8 0.2 23.1 7.9 8.4 25.4 4.7 3.4 1.0 10.9 10.4 3.4 9.1 3.0 5.6 4.9 7.2 5.5 5.2 11.4 4.0 8.2 3.4 4.7 10.0 6.2 11.9 6.5 0.0 0.3 0.1 0.3 0.2 0.7 0.4 0.4 0.5 0.8 0.5 0.7 0.6 0.0 0.8 0.1 0.4 0.1 0.3 0.2 0.3 0.7 1.3 0.3 0.4 0.2 0.5 0.4 0.1 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 ME1 ENSG00000065833 "Malic enzyme 1" P48163 6 83210402-83431051 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 71.8;Excitatory neurons: 117.1;Inhibitory neurons: 70.6;Kupffer cells: 74.4;Muller glia cells: 100.6;Oligodendrocyte precursor cells: 123.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "MAIT T-cell: 16.0" "Lineage enriched" "Detected in many" 10 "T-cells: 16.0" "Cell line enhanced" "Detected in many" "CACO-2: 139.4;OE19: 158.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006493 Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA006493: AB_1078272" "unprognostic (7.21e-2)" "unprognostic (3.99e-2)" "unprognostic (2.24e-1)" "unprognostic (3.12e-3)" "prognostic unfavorable (7.73e-4)" "unprognostic (7.98e-3)" "prognostic unfavorable (4.57e-5)" "unprognostic (3.24e-1)" "unprognostic (4.44e-3)" "unprognostic (1.41e-3)" "unprognostic (7.10e-3)" "unprognostic (2.43e-1)" "prognostic unfavorable (1.81e-7)" "unprognostic (4.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.85e-2)" "unprognostic (4.51e-2)" 41.4 44.4 13.4 5.2 15.4 0.4 29.9 14.5 18.1 8.0 8.5 7.7 21.7 4.2 6.5 28.6 4.2 15.5 18.6 13.1 17.4 3.6 9.8 8.8 4.2 15.0 19.1 10.8 3.4 19.9 12.5 2.9 18.3 8.4 11.0 30.0 10.3 17.2 34.7 14.4 10.4 7.8 13.4 7.3 23.8 16.1 16.8 5.6 6.7 30.5 4.5 15.3 12.0 13.5 29.0 59.1 1.4 0.0 48.0 44.4 0.1 18.4 47.0 19.2 37.1 139.4 24.9 0.0 46.8 43.4 38.2 29.8 43.4 16.4 20.9 0.0 24.4 0.0 33.8 0.0 61.4 14.3 50.3 49.0 32.3 38.7 26.3 32.1 30.4 0.0 20.4 0.1 26.4 32.7 0.0 16.2 0.0 158.3 23.0 0.0 48.5 27.9 56.8 13.7 5.8 14.9 31.2 45.7 1.0 25.0 0.0 34.5 32.4 11.9 14.1 3.9 0.1 10.9 13.3 0.1 0.0 0.0 35.9 0.0 1.6 0.0 0.8 0.3 16.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 13.4 15.4 14.5 18.1 13.1 17.4 15.0 19.1 18.3 13.4 16.8 13.5 0.9 19.2 12.1 71.8 0.6 1.9 5.1 12.5 6.8 17.1 2.5 0.9 41.0 7.2 12.7 5.5 2.1 0.6 0.5 12.7 1.9 12.3 5.5 0.7 6.8 2.3 0.0 0.0 117.1 9.5 0.9 8.5 62.7 0.2 0.0 11.2 4.2 12.1 7.1 13.5 70.6 4.1 8.2 74.4 25.6 6.5 25.7 16.7 0.0 23.4 5.5 100.6 0.0 123.6 38.6 15.0 4.5 37.2 0.5 5.2 15.2 3.1 7.2 7.5 0.0 4.5 8.3 7.5 2.3 22.3 3.4 0.8 1.8 33.6 8.9 3.3 MEF2B RSRFR2 ENSG00000213999 "Myocyte enhancer factor 2B" Q02080 19 19145567-19192131 "Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "lymphoid tissue: 39.3" "Cell type enriched" "Detected in some" 4 "Plasma cells: 29.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 10 "Daudi: 223.4;U-266/70: 217.6;U-698: 299.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA004734 Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA004734: AB_10963939" "unprognostic (7.31e-3)" "unprognostic (4.06e-2)" "unprognostic (9.44e-5)" "unprognostic (5.07e-2)" "unprognostic (2.01e-1)" "unprognostic (7.19e-3)" "unprognostic (1.64e-1)" "unprognostic (1.78e-1)" "unprognostic (2.76e-1)" "unprognostic (1.98e-2)" "unprognostic (8.66e-3)" "unprognostic (1.92e-2)" "unprognostic (1.56e-11)" "unprognostic (2.40e-1)" "unprognostic (1.92e-1)" "unprognostic (3.68e-1)" "unprognostic (8.98e-3)" 3.0 1.8 4.4 13.9 5.4 2.3 2.6 4.4 6.1 4.0 4.4 3.1 1.8 2.3 0.7 2.2 3.5 1.4 2.2 4.5 4.7 2.7 3.8 2.6 39.3 5.2 4.9 3.9 1.5 0.4 2.6 1.0 4.8 4.5 1.1 0.9 2.6 1.3 1.0 2.8 4.9 1.3 4.3 8.8 2.6 3.2 5.2 1.8 3.4 0.7 31.5 2.3 3.3 6.1 2.3 0.5 1.5 2.1 1.3 2.5 2.2 1.3 0.9 1.8 2.2 0.0 3.2 223.4 1.0 0.9 0.5 2.0 0.3 0.8 0.3 1.0 5.1 1.4 0.6 1.1 2.8 1.2 2.0 1.0 1.8 1.1 1.6 1.0 0.1 4.2 0.9 3.9 0.8 3.9 1.6 1.8 0.2 0.2 12.8 4.6 0.9 5.2 0.5 0.3 0.3 1.8 2.5 0.3 1.7 0.0 0.0 2.5 0.7 1.1 4.0 6.9 1.8 217.6 24.0 299.5 2.6 3.9 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 4.4 5.4 4.4 6.1 4.5 4.7 5.2 4.9 4.8 4.3 5.2 6.1 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 29.3 0.0 0.0 0.0 0.0 0.0 6.6 0.0 1.4 0.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 MEIOC "C17orf104, FLJ35848" ENSG00000180336 "Meiosis specific with coiled-coil domain" A2RUB1 17 44656404-44690308 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 21 "testis: 47.7" "Cell type enhanced" "Detected in some" "Early spermatids: 274.0;Late spermatids: 545.2;Spermatocytes: 242.4;Spermatogonia: 125.5" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 16.9;HMC-1: 25.4;NTERA-2: 8.7;SiHa: 9.5;SuSa: 12.0;THP-1: 12.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA027266 Enhanced Uncertain "Cell Junctions" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Cell Junctions" "HPA027266: AB_1848900" "unprognostic (5.82e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.96e-2)" "unprognostic (9.12e-2)" "unprognostic (2.31e-1)" "unprognostic (2.13e-1)" "unprognostic (3.63e-2)" "unprognostic (8.89e-2)" "unprognostic (7.58e-2)" "unprognostic (6.83e-4)" "unprognostic (1.85e-1)" "unprognostic (6.24e-3)" "unprognostic (1.72e-1)" "unprognostic (1.75e-1)" "unprognostic (9.91e-3)" "unprognostic (8.89e-3)" 0.2 0.2 0.2 0.2 0.4 0.8 0.3 1.0 0.7 0.3 0.0 0.3 0.2 0.2 0.0 0.3 0.2 0.2 0.4 0.5 0.1 0.7 0.7 0.2 0.5 0.1 0.0 0.3 0.2 0.2 0.3 0.1 0.2 0.3 0.0 1.6 0.3 0.0 2.2 0.9 0.3 0.0 0.0 0.3 0.2 47.7 0.1 0.0 0.3 0.0 0.1 0.3 0.2 0.4 0.2 7.7 1.0 1.3 0.2 0.0 0.5 1.0 0.0 0.6 2.1 0.4 0.3 0.8 1.9 0.5 0.2 0.2 16.9 0.0 0.2 0.7 6.8 0.6 0.9 0.4 0.0 0.6 25.4 0.0 0.0 0.9 0.0 1.7 0.0 1.6 0.5 0.7 0.2 1.5 0.5 1.5 8.7 0.2 0.7 0.3 0.8 0.5 0.0 0.2 1.7 2.1 9.5 0.2 0.1 12.0 1.1 12.9 0.3 0.4 0.3 1.9 0.8 0.6 1.1 0.2 0.6 0.9 1.5 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.1 0.3 0.1 0.1 0.3 0.1 0.0 0.2 0.4 1.0 0.7 0.5 0.1 0.1 0.0 0.2 0.0 0.1 0.4 0.2 0.0 1.1 0.0 0.4 0.0 1.0 0.0 1.2 2.0 0.5 0.6 0.0 0.0 0.0 0.0 2.1 0.2 0.8 0.0 3.9 0.1 274.0 0.9 0.7 0.6 0.0 0.8 0.0 0.2 0.4 0.4 0.5 1.0 0.0 0.6 0.0 1.0 0.4 0.0 0.0 0.1 0.0 1.3 0.0 545.2 4.7 0.8 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.2 0.0 3.8 0.4 0.6 0.1 1.2 0.0 2.6 19.7 1.2 0.3 242.4 125.5 0.2 0.0 0.3 0.6 0.3 0.2 0.8 MEPCE "BCDIN3, FLJ20257" ENSG00000146834 "Methylphosphate capping enzyme" Q7L2J0 7 100428790-100434118 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026384, HPA051587" Supported Approved "Nucleoplasm,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Nucleoplasm "Cell Junctions" "CAB026384: , HPA051587: AB_2681544" "unprognostic (8.59e-2)" "unprognostic (1.23e-2)" "unprognostic (3.77e-2)" "prognostic unfavorable (6.01e-6)" "unprognostic (1.09e-1)" "unprognostic (1.53e-2)" "unprognostic (3.83e-2)" "unprognostic (2.19e-1)" "unprognostic (1.69e-2)" "unprognostic (2.95e-1)" "unprognostic (1.65e-3)" "unprognostic (1.09e-1)" "prognostic favorable (1.01e-10)" "unprognostic (9.66e-2)" "unprognostic (9.31e-2)" "unprognostic (4.57e-1)" "unprognostic (9.50e-3)" 26.4 41.0 27.5 19.4 28.3 28.3 24.2 30.4 31.5 26.1 23.6 25.8 18.5 28.8 27.8 27.5 27.0 19.4 26.8 26.7 27.0 37.0 36.9 21.9 29.0 27.6 27.3 36.0 22.5 35.0 23.6 20.9 27.4 26.5 12.9 9.9 24.9 20.7 38.5 34.5 27.2 18.0 26.8 56.6 24.6 79.8 28.0 28.1 36.5 31.5 24.2 28.3 21.9 28.2 42.6 53.6 38.9 41.9 36.8 36.7 29.1 46.4 66.5 48.7 37.4 43.8 60.1 87.1 75.5 29.1 38.5 38.4 43.0 34.9 32.0 39.4 49.4 45.1 41.5 33.3 30.9 58.0 53.0 38.2 40.9 55.7 70.0 26.5 41.1 27.4 90.6 62.2 47.2 155.6 66.3 129.8 72.1 35.0 58.9 53.0 31.5 79.1 32.7 25.6 58.5 50.6 72.5 139.1 49.1 19.3 35.6 52.1 36.2 81.5 63.5 55.9 62.0 41.0 42.4 96.3 45.8 71.1 72.9 2.6 2.6 3.7 3.8 2.3 4.6 6.2 4.4 4.2 3.3 6.6 6.2 5.5 6.4 5.9 1.9 6.3 4.5 7.5 27.5 28.3 30.4 31.5 26.7 27.0 27.6 27.3 27.4 26.8 28.0 28.2 34.2 9.6 18.9 5.5 33.8 30.2 17.3 7.1 19.9 9.9 30.2 21.6 25.6 20.0 7.8 22.0 8.4 15.8 34.3 32.2 15.6 10.3 29.6 18.3 13.1 21.7 10.7 9.9 2.8 12.0 8.5 17.3 54.6 18.8 18.3 14.5 28.9 22.1 12.7 11.8 2.6 26.1 8.2 26.7 16.9 66.5 17.4 32.9 8.8 7.5 18.1 19.4 15.5 2.5 2.7 10.4 23.6 15.4 14.9 15.6 39.9 14.4 10.4 9.5 6.6 35.0 17.9 44.8 15.1 22.3 25.1 21.2 25.0 19.5 20.3 9.9 MERTK "c-Eyk, mer, RP38, Tyro12" ENSG00000153208 "MER proto-oncogene, tyrosine kinase" Q12866 2 111898607-112029561 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Disease variant, Proto-oncogene, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 162.6;Kupffer cells: 119.8;Macrophages: 46.5;Microglial cells: 124.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "intermediate monocyte: 8.6;non-classical monocyte: 5.5" "Lineage enriched" "Detected in single" 50 "monocytes: 8.6" "Cell line enhanced" "Detected in many" "CACO-2: 35.1;Hep G2: 39.9;HUVEC TERT2: 38.4;RT4: 23.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036196, HPA075622" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Midbody,Cytosol" Yes NA 65000000 "Cluster 7: Monocytes - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Endoplasmic reticulum, Midbody, Cytosol" "HPA036196: AB_10670676, HPA075622: AB_2686759" "unprognostic (2.17e-2)" "unprognostic (8.10e-2)" "unprognostic (4.85e-2)" "unprognostic (2.68e-1)" "unprognostic (2.44e-1)" "unprognostic (1.77e-1)" "unprognostic (1.07e-1)" "prognostic favorable (4.74e-4)" "unprognostic (6.84e-2)" "unprognostic (1.25e-1)" "unprognostic (6.22e-2)" "unprognostic (3.72e-1)" "prognostic favorable (4.43e-5)" "unprognostic (5.13e-2)" "unprognostic (2.11e-1)" "unprognostic (5.86e-2)" "unprognostic (2.05e-2)" 20.1 59.8 22.8 13.5 28.0 1.5 15.3 18.0 29.3 12.6 44.7 10.9 12.3 11.5 26.3 8.4 15.5 12.0 7.0 22.0 22.5 11.4 21.0 13.6 13.1 23.5 22.3 12.6 9.9 21.2 15.5 20.1 22.4 14.1 7.9 16.6 6.4 16.3 3.2 6.4 14.3 14.4 18.4 30.6 13.9 17.2 30.1 6.8 10.1 4.6 8.9 13.6 9.4 22.0 1.0 1.7 7.6 17.3 0.4 0.2 12.3 0.0 0.2 1.0 1.7 35.1 2.2 0.1 8.1 0.1 7.9 0.2 10.2 0.0 1.4 1.5 5.5 7.0 0.0 39.9 0.3 0.2 1.5 0.5 0.0 8.9 0.6 4.0 38.4 1.5 2.2 3.5 2.9 1.8 0.0 9.1 4.8 1.1 6.0 2.9 2.1 3.0 19.4 23.4 0.3 7.2 0.2 0.5 3.2 2.7 0.0 0.4 5.8 1.0 3.4 0.1 0.0 3.1 4.8 0.1 0.0 1.4 0.0 0.0 0.6 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 5.5 0.1 0.0 0.2 22.8 28.0 18.0 29.3 22.0 22.5 23.5 22.3 22.4 18.4 30.1 22.0 8.8 3.2 27.7 162.6 1.7 1.7 2.9 0.3 1.8 0.6 2.1 4.3 2.7 2.8 6.4 0.0 2.1 3.3 0.4 1.2 1.9 1.1 2.3 8.0 4.7 10.2 0.0 0.4 5.0 1.0 1.1 3.2 0.5 12.1 0.0 3.8 28.5 9.2 25.5 0.0 7.0 2.0 0.0 119.8 1.8 2.7 5.0 46.5 0.0 124.6 1.5 7.7 0.0 10.6 0.6 1.2 1.9 6.8 10.8 2.9 4.4 1.9 1.5 11.3 6.6 1.5 9.2 0.6 1.5 0.6 1.3 18.9 1.3 3.5 1.9 1.6 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METAP1 "KIAA0094, MAP1A, MetAP1A" ENSG00000164024 "Methionyl aminopeptidase 1" P53582 4 98995659-99062809 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 4 "Late spermatids: 1627.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025485, HPA037997, HPA037998" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 8900 "Cluster 44: Non-specific - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Nucleoplasm, Plasma membrane" "CAB025485: , HPA037997: AB_2675777, HPA037998: AB_2675778" "unprognostic (1.79e-1)" "unprognostic (3.39e-1)" "prognostic favorable (7.22e-4)" "unprognostic (1.58e-2)" "unprognostic (6.53e-2)" "unprognostic (2.15e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (1.09e-1)" "unprognostic (1.51e-3)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.28e-5)" "unprognostic (2.00e-1)" "prognostic favorable (1.72e-4)" "unprognostic (5.50e-2)" "unprognostic (8.51e-2)" "unprognostic (1.15e-3)" "prognostic favorable (9.31e-4)" 14.8 9.5 10.2 20.5 11.6 25.1 28.7 10.5 13.8 24.0 8.8 31.8 24.1 25.7 43.7 52.3 24.3 15.1 41.1 11.2 10.0 24.7 24.0 15.6 24.9 9.5 10.1 14.0 19.5 14.0 11.6 16.9 9.4 29.2 33.5 11.3 23.1 29.7 33.8 28.7 23.4 25.7 9.2 17.6 19.6 51.6 10.6 41.9 18.8 28.7 31.2 34.5 30.8 10.4 57.6 55.9 47.7 51.7 37.2 59.1 52.9 80.3 51.5 67.1 63.7 62.9 83.3 84.1 31.3 65.5 40.3 56.1 84.8 80.5 92.9 59.2 39.9 75.6 37.8 68.2 40.2 103.6 60.8 42.8 57.5 57.0 60.4 52.4 56.3 46.9 60.0 49.7 73.2 44.0 90.9 49.3 58.7 97.7 44.3 58.9 74.5 45.4 109.2 73.6 64.7 38.5 27.0 82.5 32.8 53.1 31.6 39.3 46.1 53.9 68.0 49.9 70.9 35.5 53.5 66.2 46.5 51.9 54.8 19.1 11.6 5.7 17.7 14.6 23.1 16.0 18.0 17.6 14.9 11.4 17.4 15.8 2.9 17.7 14.7 7.2 17.7 14.1 10.2 11.6 10.5 13.8 11.2 10.0 9.5 10.1 9.4 9.2 10.6 10.4 16.1 41.7 14.6 20.2 19.8 42.4 47.5 26.2 51.2 5.2 21.0 24.9 57.0 17.2 19.5 14.7 2.1 24.4 17.4 36.7 13.7 28.4 330.3 45.4 30.0 17.3 7.8 24.2 22.6 29.4 70.5 15.3 22.4 60.9 3.8 16.9 12.8 21.4 17.2 3.3 15.0 23.3 24.4 20.2 16.2 1627.3 19.3 17.4 16.0 14.0 13.9 10.6 25.7 17.6 22.3 28.0 30.8 22.6 17.8 34.4 25.3 31.6 17.2 3.7 26.3 11.5 21.7 15.7 41.6 54.3 38.8 7.7 23.6 18.1 36.2 46.9 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" NA NA 70000 "Cluster 6: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 52.5 58.0 41.1 51.6 44.5 102.2 55.0 45.0 53.2 46.0 39.7 50.7 36.7 54.2 52.6 54.7 42.6 47.0 65.9 40.2 49.9 55.6 84.5 49.0 78.0 46.5 43.8 60.5 52.7 52.3 36.6 51.3 48.8 43.3 50.9 30.8 40.6 101.0 119.5 58.3 37.7 54.9 42.4 40.3 37.4 61.8 44.7 69.1 51.8 78.7 125.0 62.2 41.5 50.2 192.3 157.8 163.7 129.6 98.4 156.4 125.9 186.0 127.6 177.7 125.7 228.0 88.6 542.1 113.5 133.4 101.9 120.5 187.4 142.4 203.8 131.2 161.2 244.9 113.7 165.6 104.5 313.5 117.1 137.5 148.1 164.9 164.0 210.7 192.9 184.2 321.8 60.5 135.3 125.8 230.3 213.0 204.5 109.4 233.4 179.6 141.5 178.5 123.5 198.3 127.0 165.3 166.0 132.7 169.0 140.6 159.4 146.5 165.1 100.7 98.5 115.0 195.7 87.7 246.8 585.1 58.1 173.7 129.9 77.5 70.5 32.0 60.0 52.2 74.3 114.2 66.8 67.8 66.0 101.8 79.2 74.1 3.4 72.8 65.6 85.3 71.6 46.4 41.1 44.5 45.0 53.2 40.2 49.9 46.5 43.8 48.8 42.4 44.7 50.2 87.0 282.0 238.9 22.9 101.3 233.2 130.2 141.3 97.3 70.6 119.7 95.9 143.6 100.1 133.3 290.6 66.7 146.2 87.7 96.8 164.4 115.2 189.5 114.9 260.0 110.2 91.7 278.4 35.1 145.8 161.5 112.2 53.0 153.7 122.9 140.5 112.1 314.6 98.1 75.7 49.5 119.7 73.2 141.0 89.8 123.3 100.3 83.8 92.5 20.6 103.5 72.6 81.4 26.2 41.4 130.1 105.8 106.8 87.0 108.1 93.4 186.6 92.4 83.8 98.6 137.4 133.4 378.4 207.6 95.2 215.0 172.0 80.7 101.4 144.8 110.5 METTL15 "FLJ33979, METT5D1" ENSG00000169519 "Methyltransferase like 15" A6NJ78 11 28108248-28527041 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 130.2;Oligodendrocyte precursor cells: 132.7;Oligodendrocytes: 146.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039885 Approved "Golgi apparatus,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "Actin filaments" "HPA039885: AB_2676725" "unprognostic (2.57e-1)" "unprognostic (2.64e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-2)" "unprognostic (2.66e-2)" "unprognostic (1.83e-1)" "unprognostic (4.17e-2)" "unprognostic (1.95e-1)" "unprognostic (2.94e-2)" "unprognostic (7.93e-2)" "unprognostic (6.31e-3)" "unprognostic (2.28e-1)" "prognostic favorable (7.95e-5)" "unprognostic (7.77e-2)" "unprognostic (1.38e-1)" "unprognostic (6.58e-2)" "unprognostic (6.84e-3)" 4.3 8.1 4.8 4.1 4.5 2.3 6.2 5.5 5.4 6.1 6.1 7.0 5.1 5.0 5.7 4.6 5.7 4.5 7.7 4.9 5.4 7.7 9.3 4.3 5.3 4.9 4.8 5.9 4.4 7.0 4.2 5.1 5.2 6.3 6.9 7.0 4.5 5.6 8.7 5.1 5.1 4.5 4.5 4.3 5.4 3.3 5.2 5.2 7.6 11.2 5.3 4.4 3.3 6.2 8.8 9.2 9.3 7.1 11.3 18.0 6.5 10.6 8.1 10.6 10.9 6.3 5.9 20.2 6.2 8.8 6.7 7.3 12.3 10.9 20.2 12.5 10.8 6.4 6.5 7.3 12.6 12.1 5.6 10.2 16.0 5.9 15.1 11.5 10.3 6.7 13.7 8.9 12.6 6.0 8.4 7.4 7.2 9.2 6.8 4.5 20.2 7.4 15.8 5.0 8.2 6.7 8.8 7.8 12.7 8.9 15.4 7.4 7.8 9.6 7.4 12.3 9.4 6.0 7.6 11.7 13.5 12.0 10.6 2.1 1.4 3.7 2.2 1.0 2.7 3.6 2.6 2.9 1.7 1.8 2.8 3.6 0.6 4.4 1.2 1.8 3.1 1.5 4.8 4.5 5.5 5.4 4.9 5.4 4.9 4.8 5.2 4.5 5.2 6.2 16.5 12.8 24.3 130.2 21.3 44.0 38.1 37.1 23.9 13.6 21.6 15.0 14.3 14.3 20.3 11.0 18.8 11.3 28.7 18.2 11.7 10.6 34.5 19.6 24.7 15.7 9.6 17.0 96.8 11.8 14.1 23.5 16.3 28.2 5.1 18.1 12.8 15.0 10.4 13.5 93.9 17.6 10.2 14.2 50.7 12.6 10.8 17.9 14.2 105.9 6.1 8.7 19.6 132.7 146.1 9.9 13.3 8.2 21.0 57.2 13.0 14.9 18.9 16.1 6.6 60.7 23.2 17.9 10.0 17.4 35.7 8.5 35.5 21.3 16.2 53.1 METTL25 "C12orf26, FLJ22789" ENSG00000127720 "Methyltransferase like 25" Q8N6Q8 12 82358528-82479239 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 23.5" "Group enriched" "Detected in many" 4 "Astrocytes: 68.2;Excitatory neurons: 63.2;Inhibitory neurons: 58.4;Microglial cells: 45.9;Oligodendrocyte precursor cells: 89.0;Oligodendrocytes: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039534, HPA041207" Enhanced Uncertain "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Mitochondria, Cytosol" "HPA039534: AB_10794749, HPA041207: AB_10794406" "unprognostic (1.60e-2)" "unprognostic (3.36e-3)" "unprognostic (2.06e-2)" "unprognostic (4.15e-2)" "unprognostic (1.56e-1)" "unprognostic (3.15e-1)" "unprognostic (5.73e-3)" "unprognostic (1.21e-2)" "unprognostic (5.20e-2)" "unprognostic (6.66e-2)" "unprognostic (7.00e-3)" "unprognostic (2.15e-2)" "unprognostic (2.59e-3)" "unprognostic (1.48e-1)" "unprognostic (1.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.44e-2)" 3.1 3.1 2.5 3.0 3.2 3.1 5.7 2.7 23.5 3.9 3.3 4.1 4.1 3.7 4.5 3.5 3.6 2.8 4.7 3.2 4.4 4.5 2.5 3.5 4.8 14.0 1.9 5.4 2.6 4.1 2.6 3.5 10.5 3.2 4.7 6.0 4.2 2.9 4.5 3.6 3.1 3.4 1.0 3.7 2.8 5.9 6.8 4.3 4.7 3.7 4.0 3.6 3.1 14.0 1.2 2.8 3.8 0.9 4.0 4.6 3.6 5.6 3.3 2.9 2.2 3.1 3.0 7.3 1.2 4.3 0.7 1.2 7.5 1.0 1.9 6.3 5.6 3.7 1.4 3.4 2.3 6.4 4.1 3.5 3.4 1.0 0.0 5.8 6.2 2.6 2.3 3.1 3.1 4.1 2.7 5.5 5.6 3.2 1.0 1.7 2.2 3.9 9.2 3.9 2.7 2.1 2.2 3.5 3.7 3.0 2.9 6.0 2.5 1.4 1.4 2.3 3.3 3.9 2.4 2.9 2.2 3.9 3.0 19.0 6.5 3.9 4.3 6.0 6.1 5.3 4.6 3.7 4.9 7.2 6.0 4.9 12.2 10.0 5.5 11.1 4.3 3.6 2.5 3.2 2.7 23.5 3.2 4.4 14.0 1.9 10.5 1.0 6.8 14.0 7.9 9.6 9.6 68.2 7.6 4.6 7.3 12.4 4.6 7.0 8.1 8.5 12.7 8.6 8.4 3.7 6.2 11.8 11.5 5.5 7.9 5.5 4.9 5.6 6.6 7.0 7.3 1.7 63.2 3.2 5.4 7.4 8.2 5.9 3.8 7.1 10.8 4.5 5.6 3.3 58.4 4.1 12.2 3.8 5.2 1.7 4.7 6.4 5.4 45.9 14.7 4.2 4.1 89.0 98.9 4.3 5.6 10.5 11.6 3.4 6.3 8.4 12.7 11.5 0.0 12.3 7.2 12.9 9.5 10.6 6.1 7.8 6.4 8.7 6.0 4.4 METTL9 DREV1 ENSG00000197006 "Methyltransferase like 9" Q9H1A3 16 21597218-21657473 "Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal tubular cells: 414.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA053588, HPA056347" Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cell Junctions" Cytosol "HPA053588: AB_2682203, HPA056347: " "unprognostic (1.55e-1)" "unprognostic (2.18e-2)" "unprognostic (1.98e-3)" "unprognostic (5.43e-2)" "unprognostic (5.81e-2)" "unprognostic (3.13e-1)" "prognostic unfavorable (8.71e-4)" "unprognostic (3.44e-2)" "unprognostic (1.11e-2)" "unprognostic (7.57e-3)" "unprognostic (1.73e-2)" "unprognostic (3.18e-1)" "unprognostic (1.49e-3)" "unprognostic (2.14e-1)" "unprognostic (3.28e-1)" "unprognostic (5.17e-2)" "unprognostic (1.65e-1)" 63.6 100.6 41.9 31.1 52.7 118.7 54.5 39.5 53.2 62.9 53.1 45.2 28.3 46.3 70.5 67.8 42.4 32.9 42.0 44.9 41.7 140.8 16.5 49.2 36.1 44.7 43.4 48.6 39.7 68.1 44.7 36.8 40.3 45.6 31.1 38.6 49.8 28.0 77.4 51.5 39.2 33.1 47.1 54.7 44.3 11.0 46.5 56.9 52.7 52.9 44.1 49.5 57.5 48.2 50.8 41.8 95.3 77.0 99.5 156.2 36.1 85.7 103.8 58.8 68.5 30.4 79.9 92.4 64.8 132.6 53.3 33.0 61.1 71.4 71.2 70.5 72.0 41.1 34.1 120.6 75.1 35.8 81.0 111.6 76.6 54.3 81.1 119.4 111.4 97.8 61.8 57.6 112.3 60.2 93.7 71.2 87.6 60.8 64.0 124.8 80.8 82.7 116.3 44.5 61.8 116.0 66.1 53.1 195.0 65.6 44.5 16.7 75.0 96.9 43.9 62.2 49.5 72.8 102.8 71.4 107.6 80.8 66.3 111.0 75.7 33.4 11.4 14.3 13.5 18.3 19.0 21.1 42.5 20.6 20.4 16.2 36.1 17.0 12.0 14.3 20.4 28.8 41.9 52.7 39.5 53.2 44.9 41.7 44.7 43.4 40.3 47.1 46.5 48.2 82.4 19.2 26.1 32.3 66.9 71.8 89.5 143.8 51.2 52.6 77.7 61.7 53.6 34.3 81.3 86.5 45.9 79.4 94.3 49.6 281.8 119.5 7.8 56.4 68.9 89.2 84.9 146.9 48.2 122.9 124.2 67.6 42.8 64.7 47.7 70.0 98.6 11.2 95.8 45.4 37.8 80.4 101.7 181.7 103.3 6.3 63.3 124.2 104.9 40.3 270.1 92.9 109.2 34.2 28.3 114.9 51.5 65.1 58.0 149.4 81.1 414.2 50.4 43.7 65.7 48.9 108.8 17.1 25.1 74.7 77.0 139.1 111.4 57.4 80.5 142.9 MFAP3L "KIAA0626, NYD-sp9" ENSG00000198948 "Microfibril associated protein 3 like" O75121 4 169986597-170033031 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.5;choroid plexus: 88.8" "Cell type enriched" "Detected in many" 4 "Late spermatids: 1840.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 5.7;eosinophil: 1.8;neutrophil: 3.5" "Lineage enriched" "Detected in single" 8 "granulocytes: 5.7" "Cell line enhanced" "Detected in many" "HMC-1: 22.5;RT4: 38.0;SK-BR-3: 34.3;SuSa: 19.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017986, HPA062306, HPA077490" Enhanced Supported "Nucleoplasm,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Cell Junctions" "HPA017986: AB_1853842, HPA062306: , HPA077490: AB_2686842" "unprognostic (8.04e-3)" "unprognostic (8.67e-3)" "unprognostic (3.74e-1)" "unprognostic (1.28e-2)" "unprognostic (4.51e-2)" "unprognostic (7.92e-2)" "unprognostic (3.50e-2)" "unprognostic (3.14e-2)" "unprognostic (2.67e-1)" "unprognostic (2.33e-1)" "unprognostic (3.96e-1)" "unprognostic (7.58e-2)" "prognostic favorable (1.42e-8)" "unprognostic (6.59e-3)" "unprognostic (2.12e-1)" "unprognostic (1.62e-4)" "unprognostic (2.40e-3)" 2.0 3.4 32.9 0.9 61.0 3.2 12.0 49.1 34.4 13.0 88.8 2.7 0.6 5.1 38.9 0.8 4.2 2.6 1.7 35.2 40.1 30.0 37.4 2.7 0.9 46.3 58.3 0.6 1.5 6.5 4.1 3.0 48.5 2.8 2.0 25.0 2.1 12.8 5.1 24.5 1.0 4.1 38.8 1.5 1.3 46.3 54.9 0.6 2.8 2.3 0.5 10.1 1.8 65.5 0.4 5.7 3.0 3.1 2.6 1.3 1.1 6.2 0.9 2.8 2.5 1.9 0.4 0.0 0.2 9.6 5.4 2.9 10.9 1.4 1.2 0.0 4.7 0.0 6.7 2.4 1.4 0.0 22.5 1.8 3.4 0.3 1.0 1.5 0.3 3.5 0.9 1.1 5.8 3.4 1.0 0.8 3.1 0.7 4.7 0.0 1.8 0.0 8.1 38.0 2.5 5.5 5.1 34.3 11.6 19.1 1.9 0.0 0.2 2.9 11.2 5.5 11.9 0.6 0.0 0.0 7.5 1.2 11.4 5.7 0.1 1.8 0.6 0.7 0.3 0.0 0.5 0.1 0.2 0.0 0.2 0.1 3.5 0.0 0.0 0.5 0.1 4.6 32.9 61.0 49.1 34.4 35.2 40.1 46.3 58.3 48.5 38.8 54.9 65.5 1.0 0.0 5.6 112.6 0.6 2.5 0.4 0.1 2.8 12.2 8.5 9.7 3.4 0.0 0.2 36.8 20.9 3.1 0.2 0.6 5.9 0.5 417.5 8.5 1.1 2.0 2.4 11.2 36.3 1.1 1.0 0.6 0.0 12.4 4.5 11.0 3.3 49.1 1.2 3.3 25.0 0.3 0.0 1.0 0.7 1840.0 5.3 13.5 7.2 3.7 1.5 2.9 2.1 53.8 127.6 1.4 0.3 9.1 0.5 0.9 0.3 24.0 0.3 15.8 19.7 1.7 4.2 17.6 13.2 0.3 8.4 9.4 0.6 1.4 0.8 2.2 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MFSD2A "FLJ14490, MFSD2" ENSG00000168389 "Major facilitator superfamily domain containing 2A" Q8NA29 1 39955112-39969968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Lipid transport, Symport, Transport" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 96.9;liver: 162.0;skin 1: 87.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 136.2;Hepatocytes: 299.6;Proximal enterocytes: 235.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "classical monocyte: 13.2;intermediate monocyte: 6.6;myeloid DC: 14.7;plasmacytoid DC: 24.3" "Group enriched" "Detected in many" 12 "dendritic cells: 24.3;monocytes: 13.2" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 52.0;THP-1: 169.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043107 Uncertain Approved "Plasma membrane,Cytosol,Cytoplasmic bodies" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane, Cytoplasmic bodies" "HPA043107: AB_10794387" "unprognostic (2.20e-1)" "unprognostic (1.15e-1)" "unprognostic (5.23e-3)" "unprognostic (1.06e-1)" "unprognostic (1.30e-1)" "unprognostic (6.92e-2)" "unprognostic (2.61e-2)" "unprognostic (2.45e-2)" "unprognostic (1.60e-1)" "unprognostic (4.33e-1)" "unprognostic (2.85e-1)" "unprognostic (1.06e-1)" "prognostic unfavorable (4.22e-6)" "unprognostic (9.26e-2)" "unprognostic (4.11e-1)" "unprognostic (1.09e-1)" "prognostic favorable (2.33e-4)" 6.3 1.4 34.0 3.4 31.7 8.4 13.4 34.8 36.0 4.8 22.2 7.2 14.6 8.5 96.9 12.5 3.5 2.3 1.4 30.9 33.4 5.8 162.0 36.1 2.3 38.5 33.8 2.2 0.6 0.7 8.0 17.1 38.6 2.4 5.0 2.6 4.0 79.2 0.5 87.8 32.0 3.5 32.8 1.5 1.9 33.9 37.2 1.6 7.5 0.1 3.6 20.2 14.1 33.1 6.2 2.7 12.5 18.9 8.7 1.6 0.0 5.9 11.2 12.8 15.1 0.8 3.4 38.0 3.4 3.0 8.8 15.0 12.4 21.8 9.8 4.9 6.0 4.6 0.1 0.1 28.8 6.8 21.8 9.7 13.3 52.0 21.5 2.3 3.1 11.5 0.0 9.5 5.7 0.8 10.6 10.4 10.1 21.4 4.7 7.4 18.5 8.7 2.1 17.9 4.4 6.7 4.5 31.7 3.0 1.1 1.5 169.8 2.0 2.7 5.3 9.5 24.9 1.8 3.5 8.5 28.9 26.0 9.2 0.0 13.2 1.4 0.1 6.6 0.2 1.5 0.1 0.2 14.7 0.2 0.0 0.1 0.7 0.2 1.2 24.3 0.0 3.6 34.0 31.7 34.8 36.0 30.9 33.4 38.5 33.8 38.6 32.8 37.2 33.1 0.5 19.2 136.2 3.3 6.3 52.8 21.2 40.0 51.2 2.0 6.3 2.3 0.6 12.8 30.8 16.5 0.0 0.5 5.7 62.2 0.0 3.4 1.0 25.8 5.5 22.9 1.2 5.7 1.5 24.8 7.6 9.7 24.5 61.8 17.2 0.1 7.1 299.6 6.7 0.0 1.3 34.5 12.2 9.8 43.3 2.7 0.6 16.1 0.0 38.4 5.5 38.8 0.0 0.0 1.6 27.2 39.3 0.4 5.0 13.9 235.1 6.1 33.9 2.7 0.0 5.0 3.3 1.0 1.3 49.3 54.8 52.5 3.3 0.1 20.7 26.6 MGAT4C HGNT-IV-H ENSG00000182050 "MGAT4 family member C" Q9UBM8 12 85955666-86838904 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "epididymis: 3.7;pituitary gland: 3.1;testis: 4.7;thyroid gland: 6.2" "Group enriched" "Detected in some" 8 "Astrocytes: 876.3;Excitatory neurons: 988.4;Inhibitory neurons: 1438.9" "Cancer enriched" "Detected in single" 19 "thyroid cancer: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "NTERA-2: 6.0;SCLC-21H: 2.5;SuSa: 1.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016418 Approved Approved "Vesicles,Plasma membrane,Centriolar satellite" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Centriolar satellite" "HPA016418: AB_2732416" "unprognostic (5.23e-2)" "unprognostic (2.33e-1)" "unprognostic (1.84e-1)" "unprognostic (3.32e-4)" "unprognostic (1.07e-1)" "unprognostic (9.64e-2)" "unprognostic (5.94e-3)" "unprognostic (1.88e-1)" "unprognostic (8.05e-2)" "unprognostic (1.89e-1)" "unprognostic (6.32e-3)" "unprognostic (3.51e-2)" "unprognostic (6.85e-10)" "unprognostic (3.15e-2)" "unprognostic (1.77e-1)" "unprognostic (1.97e-1)" "unprognostic (4.74e-3)" 0.3 0.8 1.7 0.0 2.0 0.1 0.0 0.2 1.4 0.1 0.0 0.4 0.0 0.0 3.7 0.0 0.1 0.1 1.7 1.0 1.8 0.0 0.1 0.1 0.0 1.0 2.4 0.0 0.1 0.0 3.1 0.0 1.6 0.2 0.1 0.5 0.0 0.6 0.0 0.0 0.1 0.0 1.1 0.0 0.1 4.7 2.3 0.0 6.2 0.0 0.0 0.1 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 2.0 0.2 1.4 1.0 1.8 1.0 2.4 1.6 1.1 2.3 0.7 0.1 6.4 1.1 876.3 0.0 0.1 0.2 1.5 0.0 11.2 0.0 0.0 10.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 123.9 0.1 0.1 4.2 0.0 0.0 988.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1438.9 0.0 4.1 0.0 0.0 98.9 16.1 0.3 0.0 34.7 0.2 0.5 0.0 32.2 17.2 0.4 0.0 4.1 0.0 0.3 0.0 0.1 0.0 1.8 0.0 0.4 0.2 3.8 1.5 0.0 0.1 0.0 0.5 6.2 0.0 0.3 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 121.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 8.1 6.3 9.1 6.0 9.1 4.9 11.2 9.2 8.5 11.0 8.0 7.1 5.1 13.0 9.5 8.0 7.1 8.6 6.0 8.4 9.2 11.1 10.4 7.2 7.6 9.5 10.2 11.7 8.1 9.8 5.2 11.0 8.6 10.1 7.0 8.3 8.4 8.5 5.8 9.1 5.2 10.2 10.1 7.2 7.6 8.7 10.3 11.5 13.6 7.0 7.9 8.4 8.2 9.6 19.9 7.6 36.4 25.8 19.5 23.0 9.0 15.6 17.2 10.8 15.6 11.3 7.1 16.9 14.1 21.4 11.8 13.2 21.4 21.0 24.4 22.4 10.4 18.8 9.7 15.9 15.8 38.3 7.8 14.8 23.0 12.6 32.0 16.0 27.8 6.6 26.5 47.5 17.2 9.5 18.9 14.7 9.5 12.2 10.2 121.1 30.3 42.5 18.7 16.9 12.1 30.1 26.8 12.4 13.9 18.6 8.8 25.1 23.9 27.8 14.2 11.7 21.1 25.6 9.5 25.4 11.8 24.1 16.9 0.7 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.5 0.1 0.2 0.4 0.1 9.1 9.1 9.2 8.5 8.4 9.2 9.5 10.2 8.6 10.1 10.3 9.6 35.7 48.1 22.7 68.2 11.9 21.9 15.1 19.8 24.5 28.8 24.1 19.7 18.1 25.8 31.8 16.5 25.0 13.3 18.2 20.8 3.9 13.4 7.0 29.0 59.2 30.8 24.0 23.1 106.7 12.9 7.5 33.1 10.2 32.4 14.5 16.8 24.3 30.0 12.9 15.2 92.6 17.1 26.4 17.2 16.2 5.6 20.5 14.2 26.6 67.5 19.4 17.7 15.5 121.2 109.6 18.8 7.0 24.8 18.1 48.5 8.7 15.9 30.6 14.5 0.0 35.4 26.9 26.2 12.0 23.4 24.6 25.3 14.5 21.8 10.4 25.3 MICAL2 KIAA0750 ENSG00000133816 "Microtubule associated monooxygenase, calponin and LIM domain containing 2" O94851 11 12094008-12359144 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 193.5;Inhibitory neurons: 108.8;Late spermatids: 192.7;Peritubular cells: 112.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 8.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-138 MG: 109.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030437, HPA039895, HPA040438" Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 58: Brain - Synaptic function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Cytosol" "Nucleoplasm, Plasma membrane" "HPA030437: AB_10601873, HPA039895: AB_2676731, HPA040438: AB_10672896" "unprognostic (2.68e-2)" "unprognostic (1.77e-2)" "unprognostic (5.77e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (6.88e-4)" "unprognostic (2.20e-2)" "unprognostic (3.60e-2)" "unprognostic (9.32e-2)" "unprognostic (2.86e-1)" "unprognostic (1.36e-1)" "unprognostic (1.15e-2)" "unprognostic (6.47e-2)" "prognostic unfavorable (3.63e-5)" "unprognostic (4.61e-2)" "unprognostic (1.97e-1)" "unprognostic (1.21e-1)" "unprognostic (1.67e-1)" 4.7 3.8 13.9 12.2 13.6 11.6 2.5 61.6 38.1 6.9 42.6 18.8 9.8 12.3 7.2 18.6 7.4 10.0 42.2 37.8 0.0 2.3 2.9 17.5 3.3 0.0 0.0 3.9 4.1 1.0 0.2 7.3 0.0 2.9 16.3 4.0 0.8 9.6 16.8 14.0 10.8 30.8 0.0 3.3 6.7 32.5 0.0 1.9 6.1 4.1 2.5 12.4 0.3 19.9 29.1 9.7 0.4 2.7 2.3 6.8 14.2 32.1 53.7 16.2 28.3 24.3 23.3 0.2 8.4 25.3 47.7 25.0 4.0 65.1 41.6 35.9 4.8 27.5 4.1 0.9 12.8 5.3 2.7 12.7 11.1 76.0 54.6 25.3 46.9 1.6 43.5 0.8 22.9 1.2 0.3 1.6 1.2 13.6 9.8 0.3 15.2 14.2 2.1 35.5 14.3 0.8 8.6 38.6 2.9 9.9 4.5 2.3 42.6 109.6 35.0 17.4 39.6 0.9 2.6 1.5 64.3 5.2 1.4 0.1 4.2 0.5 1.3 0.7 1.5 0.1 0.8 0.4 3.4 0.2 0.0 0.4 8.9 2.2 0.4 0.9 0.7 1.5 13.9 13.6 61.6 38.1 37.8 0.0 0.0 0.0 0.0 0.0 0.0 19.9 3.2 41.7 37.1 7.2 1.2 10.1 11.8 4.5 4.0 5.7 4.2 5.3 32.2 7.2 8.5 3.7 0.0 2.6 11.2 66.5 0.0 10.2 74.4 7.8 8.9 9.2 22.6 35.6 193.5 14.3 12.6 9.0 12.2 11.4 1.3 1.4 12.8 19.6 3.4 0.0 108.8 10.6 6.1 10.1 5.6 192.7 21.1 11.1 5.4 4.7 21.6 0.5 8.2 6.6 17.5 42.5 24.0 112.8 2.1 8.9 18.3 0.9 5.5 1.6 13.1 1.9 29.4 1.2 1.3 1.7 9.5 2.3 10.8 0.7 14.5 11.9 MICAL3 KIAA0819 ENSG00000243156 "Microtubule associated monooxygenase, calponin and LIM domain containing 3" Q7RTP6 22 17787649-18024561 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Exocytosis" "Actin-binding, Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 104.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 176.5;Inhibitory neurons: 164.6;Oligodendrocytes: 216.0" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 104.9" "Immune cell enriched" "Detected in some" 4 "basophil: 11.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 11.1" "Cell line enhanced" "Detected in all" "WM-115: 131.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000639, HPA003421, HPA034882" Approved Supported "Nucleoplasm,Plasma membrane,Midbody ring,Cytosol" Yes No "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Midbody ring" "Plasma membrane, Cytosol" "HPA000639: AB_10301319, HPA003421: AB_10601134, HPA034882: AB_2674371" "unprognostic (1.65e-1)" "unprognostic (1.02e-1)" "unprognostic (3.67e-2)" "unprognostic (2.00e-2)" "unprognostic (7.68e-2)" "unprognostic (2.06e-1)" "unprognostic (4.71e-2)" "unprognostic (3.07e-3)" "unprognostic (3.41e-1)" "unprognostic (1.01e-1)" "unprognostic (4.58e-1)" "unprognostic (3.82e-1)" "unprognostic (8.86e-3)" "unprognostic (1.36e-2)" "unprognostic (1.23e-1)" "unprognostic (2.03e-2)" "unprognostic (6.64e-2)" 15.9 12.0 18.3 14.9 20.3 17.3 11.2 104.9 34.5 16.5 3.6 28.1 11.0 31.0 17.0 19.6 38.6 13.4 35.6 14.3 13.7 10.9 18.8 8.3 23.0 13.2 6.4 26.5 14.0 38.5 7.2 16.7 15.6 16.4 20.6 14.1 10.9 19.8 48.2 18.9 14.5 37.3 1.9 17.8 10.7 24.4 12.7 6.0 14.7 20.8 20.3 15.9 12.0 45.9 34.0 39.6 20.2 33.7 15.6 19.2 25.6 32.6 33.1 43.6 34.5 36.1 4.8 35.1 15.5 39.3 51.2 38.7 30.1 31.9 43.0 35.6 25.2 35.9 44.6 11.9 9.6 17.1 20.2 14.4 25.9 46.9 43.7 25.2 24.9 9.7 47.6 22.8 16.9 26.6 16.9 10.7 13.0 27.3 26.4 23.2 30.3 1.9 32.1 24.8 53.5 21.1 40.6 26.0 65.2 31.5 10.8 7.0 43.9 46.0 28.4 29.7 63.6 16.4 30.2 50.8 40.0 7.7 131.6 11.1 0.0 0.1 0.3 0.0 0.6 2.5 0.3 0.3 0.0 2.6 0.2 0.1 0.1 0.9 0.0 0.2 0.7 0.2 18.3 20.3 104.9 34.5 14.3 13.7 13.2 6.4 15.6 1.9 12.7 45.9 19.6 3.2 10.2 57.1 32.1 11.2 15.2 17.9 13.1 20.9 13.7 15.5 16.5 12.8 13.2 12.9 52.1 14.1 6.2 43.5 0.0 23.9 10.5 36.4 10.2 16.4 10.2 19.3 176.5 9.8 40.3 10.5 13.3 38.8 19.0 9.7 8.9 37.3 3.1 1.7 164.6 20.8 8.2 3.2 9.6 13.9 4.1 4.2 8.8 23.4 6.0 38.2 5.2 71.9 216.0 24.6 23.6 6.4 12.5 14.4 19.8 5.5 27.8 12.2 0.0 11.0 12.1 19.8 13.8 11.2 11.8 11.2 9.1 24.2 21.5 10.1 MICALL1 "KIAA1668, MICAL-L1, MIRAB13" ENSG00000100139 "MICAL like 1" Q8N3F8 22 37905657-37942822 "Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 39.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "hTCEpi: 101.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043480, HPA051956" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Cell Junctions, Centriolar satellite, Cytosol" "HPA043480: AB_10793950, HPA051956: AB_2681671" "unprognostic (2.13e-1)" "unprognostic (1.13e-1)" "unprognostic (4.94e-2)" "unprognostic (4.90e-1)" "unprognostic (1.57e-1)" "unprognostic (2.37e-1)" "prognostic unfavorable (3.08e-6)" "unprognostic (3.46e-2)" "unprognostic (1.04e-1)" "unprognostic (7.68e-2)" "unprognostic (2.42e-3)" "unprognostic (1.57e-2)" "unprognostic (6.96e-3)" "unprognostic (6.61e-2)" "unprognostic (8.53e-2)" "unprognostic (1.30e-1)" "unprognostic (3.92e-2)" 9.6 5.8 8.2 9.3 14.8 6.2 10.2 15.7 10.3 18.4 8.0 38.6 6.4 28.4 3.1 46.6 13.6 6.4 10.7 8.7 9.8 8.7 7.0 11.7 5.9 19.7 16.8 4.8 18.5 10.6 4.4 17.3 17.4 17.0 4.6 0.8 17.8 24.0 10.8 36.6 12.5 19.7 14.1 7.2 44.0 10.8 15.3 5.4 10.0 5.2 7.1 25.4 26.0 22.2 25.4 13.7 13.0 15.4 10.4 11.9 59.9 32.3 17.5 34.8 25.3 17.3 13.1 10.8 10.5 22.2 22.7 65.0 9.1 69.9 17.2 21.2 31.3 5.7 11.6 16.7 24.0 11.6 11.8 11.3 101.2 42.5 70.1 10.4 22.1 4.9 8.9 8.1 22.7 10.6 2.9 6.7 5.0 12.9 12.1 16.6 27.4 6.1 8.1 53.0 9.6 8.5 19.3 19.7 20.2 15.4 10.8 10.9 34.3 61.1 47.3 37.8 27.5 9.4 3.7 7.2 55.2 5.8 29.0 0.1 0.2 0.1 0.4 0.2 0.3 0.3 0.3 0.5 0.3 0.5 0.3 0.2 0.5 0.5 0.1 0.6 0.1 0.4 8.2 14.8 15.7 10.3 8.7 9.8 19.7 16.8 17.4 14.1 15.3 22.2 10.9 0.0 7.8 1.3 4.8 7.5 10.1 12.8 23.9 0.7 7.3 7.9 11.9 7.2 9.5 5.5 0.0 31.0 7.8 7.7 1.9 10.5 18.1 11.3 5.4 12.2 3.5 1.3 0.7 10.2 26.3 4.3 27.5 6.8 1.3 5.8 6.4 5.9 8.7 5.0 4.4 3.9 6.1 4.4 3.4 28.8 1.8 4.3 1.8 1.0 7.2 0.7 7.2 2.5 17.8 15.4 2.2 4.1 6.4 13.6 4.4 2.7 6.0 0.7 0.0 3.5 9.4 5.5 2.2 27.2 9.1 39.4 5.2 1.5 3.7 15.2 MICB PERB11.2 ENSG00000204516 "MHC class I polypeptide-related sequence B" Q29980 6 31494881-31511124 "Disease related genes, Predicted membrane proteins" "Adaptive immunity, Cytolysis, Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "dendritic cells: 10.3;Erythroid cells: 10.5;Hofbauer cells: 11.1;Kupffer cells: 17.8;monocytes: 13.2;T-cells: 11.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/70: 15.2;U-266/84: 36.5" HPA064618 Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 64: Macrophages - Immune response" "Cluster 16: U-266 - Nucleosome" "Cluster 63: NK-cells & T-cells - Immune response" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA064618: AB_2685301" "unprognostic (3.63e-3)" "unprognostic (8.81e-2)" "unprognostic (3.19e-1)" "unprognostic (1.51e-2)" "unprognostic (8.44e-2)" "unprognostic (5.94e-2)" "prognostic unfavorable (7.04e-5)" "unprognostic (2.05e-1)" "unprognostic (2.61e-1)" "unprognostic (1.67e-3)" "unprognostic (2.28e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (4.94e-9)" "unprognostic (1.91e-3)" "unprognostic (2.80e-2)" "unprognostic (9.72e-2)" "unprognostic (1.21e-2)" 2.6 1.2 0.1 1.4 0.2 2.2 2.2 0.2 0.4 1.4 0.2 1.9 0.2 1.7 0.3 1.4 1.2 0.4 2.5 0.2 0.1 1.8 1.2 6.2 2.8 0.2 0.1 0.7 0.8 0.1 0.6 0.2 0.2 1.1 0.5 0.0 1.3 0.0 0.5 1.0 4.5 0.4 0.1 9.9 1.4 1.3 0.3 0.7 1.6 0.7 1.6 1.4 1.5 0.2 3.4 1.3 0.0 0.0 1.9 3.2 0.1 2.3 2.2 2.9 3.7 0.0 0.4 3.9 5.9 4.3 8.1 0.8 1.0 4.1 1.0 3.4 2.3 4.6 0.6 1.3 0.7 1.4 3.5 4.1 0.8 5.0 3.5 3.1 1.9 6.0 4.2 7.8 3.5 0.0 1.3 5.9 0.4 0.0 0.5 4.7 0.0 8.2 3.8 0.2 0.0 0.0 1.5 0.0 0.7 1.2 2.0 1.6 1.9 2.2 0.0 1.9 0.1 15.2 36.5 8.3 0.5 12.0 4.9 1.8 0.9 1.2 0.8 1.1 1.0 0.6 0.8 1.1 0.6 0.5 0.4 0.9 0.9 0.6 1.6 0.4 1.4 0.7 0.1 0.2 0.2 0.4 0.2 0.1 0.2 0.1 0.2 0.1 0.3 0.2 3.0 3.2 1.5 0.0 8.2 2.9 0.5 0.3 0.0 0.0 3.1 1.9 0.5 1.5 0.8 0.0 0.0 0.1 10.3 0.8 1.9 1.6 0.0 3.1 1.6 3.0 0.0 10.5 0.6 0.7 0.3 1.5 2.0 5.2 0.0 0.1 3.9 0.1 11.1 0.0 0.1 0.6 0.0 17.8 8.2 0.4 0.3 8.0 1.8 3.7 13.2 0.0 7.2 0.0 0.1 1.9 1.9 0.4 8.7 2.1 0.5 0.3 0.9 0.0 0.0 0.6 2.2 4.6 5.2 0.1 1.1 0.1 11.3 0.5 2.1 1.1 MIEN1 "C17orf37, C35, MGC14832, ORB3, Rdx12, XTP4" ENSG00000141741 "Migration and invasion enhancer 1" Q9BRT3 17 39728496-39730532 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in all" 14 "OE19: 1667.9;SK-BR-3: 502.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056650, HPA061344" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" Nucleoplasm "HPA056650: , HPA061344: AB_2684484" "unprognostic (2.48e-1)" "unprognostic (3.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.13e-2)" "unprognostic (3.04e-1)" "unprognostic (1.17e-1)" "unprognostic (4.47e-2)" "unprognostic (8.37e-2)" "unprognostic (6.72e-2)" "unprognostic (2.03e-1)" "unprognostic (1.90e-1)" "unprognostic (3.17e-1)" "unprognostic (2.99e-2)" "unprognostic (3.70e-1)" "unprognostic (2.00e-1)" "unprognostic (3.88e-3)" "unprognostic (2.22e-3)" 29.1 35.9 33.4 17.5 35.4 27.0 31.5 36.2 44.8 31.1 34.2 42.4 26.3 29.0 14.6 47.3 27.2 12.1 49.5 32.5 35.3 57.2 53.7 29.6 20.2 34.5 34.8 18.5 40.7 21.6 39.6 13.5 34.5 46.3 12.8 4.8 46.2 13.8 47.2 35.0 37.5 9.5 32.9 36.2 48.5 41.3 35.4 13.9 37.0 5.3 13.7 31.0 32.0 37.2 38.8 59.7 13.4 34.5 16.3 12.0 16.2 40.7 21.4 24.2 23.6 12.9 27.2 28.1 55.5 15.1 39.0 47.1 15.6 13.8 8.2 58.2 65.8 26.5 29.8 36.5 28.2 33.9 39.2 10.8 23.3 11.7 12.0 18.8 15.6 52.9 38.2 48.9 14.7 22.5 70.1 38.2 12.5 1667.9 26.4 32.2 23.6 56.8 12.2 21.8 43.6 41.7 40.8 502.3 70.7 12.0 66.1 48.1 41.5 16.4 41.8 78.9 47.1 62.3 62.8 55.1 64.5 41.1 32.4 138.5 76.2 107.3 80.1 100.9 43.4 109.2 56.2 72.3 54.5 88.3 43.9 63.1 132.9 58.7 104.2 79.4 94.6 119.9 33.4 35.4 36.2 44.8 32.5 35.3 34.5 34.8 34.5 32.9 35.4 37.2 59.8 44.8 64.2 7.8 60.9 60.2 138.1 185.1 95.6 25.7 127.0 114.2 59.6 82.9 129.3 99.3 4.2 150.2 69.1 226.6 303.3 137.0 136.2 81.6 48.7 58.9 188.8 72.0 11.0 176.1 74.4 50.9 76.5 77.3 81.8 43.8 54.7 118.9 148.0 35.3 9.6 178.3 254.3 101.3 42.8 76.7 42.3 81.3 138.7 12.2 80.1 90.7 130.7 4.5 20.8 216.8 283.7 49.7 54.0 194.8 188.5 224.9 122.1 17.3 46.0 31.5 61.1 108.5 68.0 131.7 70.3 266.1 65.4 51.7 128.1 204.0 MIGA2 "C9orf54, FAM73B, FLJ00199, FLJ14596" ENSG00000148343 "Mitoguardin 2" Q7L4E1 9 129036621-129072082 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 18.7;Theca cells: 22.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041363 Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "Cell Junctions" "HPA041363: AB_10794664" "unprognostic (2.10e-1)" "unprognostic (4.82e-3)" "unprognostic (1.07e-1)" "unprognostic (2.70e-1)" "unprognostic (1.22e-1)" "unprognostic (1.35e-2)" "unprognostic (1.01e-1)" "unprognostic (3.93e-2)" "unprognostic (3.07e-3)" "unprognostic (2.90e-2)" "prognostic favorable (3.04e-6)" "unprognostic (1.12e-2)" "unprognostic (1.44e-3)" "unprognostic (8.57e-3)" "unprognostic (1.25e-1)" "unprognostic (4.63e-2)" "unprognostic (4.15e-3)" 6.7 13.6 7.5 5.3 7.6 12.6 5.8 8.4 8.1 6.2 5.1 11.8 15.2 7.2 2.9 11.9 6.7 3.9 17.3 7.0 8.4 7.8 7.8 4.8 4.6 10.4 8.3 6.8 4.7 6.6 8.1 1.6 9.1 9.3 3.1 2.3 7.3 6.9 9.8 10.1 14.0 4.3 7.0 7.0 10.1 4.6 9.1 4.4 9.2 7.7 3.6 9.3 6.3 7.6 4.8 9.7 2.9 14.9 7.9 4.1 6.5 8.4 6.3 9.5 6.0 8.4 9.8 7.2 3.7 6.6 8.3 22.3 4.0 6.3 1.4 6.6 5.9 5.2 20.4 6.3 8.7 6.0 11.5 5.8 4.9 8.6 4.4 3.1 6.6 6.7 7.7 2.9 5.2 12.7 6.0 12.3 6.7 11.4 13.9 12.2 8.7 12.0 5.0 9.2 9.3 6.6 9.4 14.7 5.2 1.7 10.6 6.4 6.7 6.1 7.0 10.4 6.5 4.0 6.2 6.7 8.7 4.7 7.4 7.2 1.5 1.4 1.5 1.6 3.3 1.2 1.1 2.0 1.6 1.3 1.1 0.7 2.5 0.6 0.9 2.2 1.0 1.2 7.5 7.6 8.4 8.1 7.0 8.4 10.4 8.3 9.1 7.0 9.1 7.6 7.1 3.2 7.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 7.1 7.2 0.0 0.0 3.1 7.3 0.0 3.3 8.1 0.0 1.9 5.4 0.0 4.2 4.4 1.8 0.0 0.0 0.0 4.7 2.6 2.4 0.0 7.3 0.0 18.7 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 5.8 0.0 0.0 1.8 0.0 0.0 4.5 2.9 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 5.6 3.0 22.1 0.0 0.0 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MKLN1 TWA2 ENSG00000128585 "Muskelin 1" Q9UL63 7 131110096-131496632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 455.1;Excitatory neurons: 336.5;Inhibitory neurons: 256.4;Oligodendrocyte precursor cells: 369.5;Oligodendrocytes: 332.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 9.5" "Lineage enriched" "Detected in many" 6 "granulocytes: 9.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022817, HPA041810" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA022817: AB_1853974, HPA041810: AB_2677686" "unprognostic (1.97e-1)" "unprognostic (2.83e-2)" "unprognostic (1.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.03e-1)" "unprognostic (4.20e-2)" "unprognostic (1.44e-3)" "unprognostic (4.58e-2)" "unprognostic (1.94e-2)" "unprognostic (1.97e-1)" "unprognostic (2.43e-3)" "unprognostic (1.55e-1)" "unprognostic (9.18e-3)" "unprognostic (1.70e-1)" "unprognostic (4.13e-1)" "unprognostic (1.13e-2)" "unprognostic (2.32e-1)" 12.6 12.1 20.0 6.9 22.3 9.1 13.6 23.1 17.8 10.8 19.1 7.5 9.0 10.1 11.8 7.5 11.9 7.1 8.9 17.1 22.3 13.8 14.7 7.6 8.8 19.4 24.7 13.8 7.7 10.0 4.6 11.6 22.8 16.0 7.3 22.0 11.3 13.4 10.5 9.6 8.4 9.0 18.8 8.7 8.4 9.5 21.4 8.6 11.3 13.5 7.7 7.2 5.4 21.5 14.1 16.0 13.6 13.8 32.8 29.6 8.5 13.3 30.7 14.8 18.8 7.3 11.9 14.6 9.0 16.7 29.3 9.5 14.4 13.1 24.2 14.5 7.0 6.2 13.1 8.5 15.7 10.4 8.7 17.7 8.8 20.6 10.0 15.9 13.7 8.8 23.3 10.2 18.6 5.2 12.3 11.1 15.5 11.4 8.3 7.7 16.0 10.1 16.4 8.1 7.0 15.2 25.7 25.7 12.9 14.1 5.0 12.9 14.1 11.5 6.5 21.1 11.0 24.7 10.0 24.6 39.6 12.3 17.2 1.2 0.7 1.4 1.1 0.9 0.8 0.9 1.1 0.9 0.8 1.6 1.7 1.4 9.5 0.7 1.3 1.2 0.7 0.5 20.0 22.3 23.1 17.8 17.1 22.3 19.4 24.7 22.8 18.8 21.4 21.5 54.4 51.3 43.7 455.1 42.6 44.1 29.3 22.9 31.9 49.7 34.6 21.5 24.9 38.6 27.4 46.0 70.9 17.3 37.6 33.2 7.9 23.0 5.7 30.5 60.4 50.5 37.1 38.9 336.5 23.7 17.4 46.3 36.7 46.9 34.2 42.9 64.2 78.3 21.7 53.8 256.4 29.4 28.5 41.9 52.1 7.8 68.0 35.1 35.6 210.8 44.9 44.1 26.8 369.5 332.5 27.1 36.5 84.2 40.2 49.3 38.7 31.4 25.9 64.9 85.5 64.3 56.9 41.1 28.0 28.9 45.9 14.8 37.9 35.9 28.4 39.1 MKRN3 "D15S9, MGC88288, RNF63, ZFP127, ZNF127" ENSG00000179455 "Makorin ring finger protein 3" Q13064 15 23565674-23630075 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1;retina: 8.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 13.8;Cone photoreceptor cells: 25.0;Horizontal cells: 6.7;Oligodendrocyte precursor cells: 6.0;Oligodendrocytes: 9.0;Rod photoreceptor cells: 7.4" "Cancer enhanced" "Detected in some" "glioma: 1.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 2.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "JURKAT: 26.3;K-562: 30.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029494 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 1: K-562 - Erythropoiesis" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoplasm "HPA029494: AB_10603873" "unprognostic (3.18e-1)" "unprognostic (1.26e-1)" "unprognostic (4.26e-1)" "unprognostic (1.86e-3)" "unprognostic (1.04e-3)" "unprognostic (1.15e-2)" "unprognostic (6.27e-4)" "unprognostic (1.51e-1)" "unprognostic (8.52e-2)" "unprognostic (7.05e-2)" "unprognostic (4.97e-3)" "unprognostic (2.86e-1)" "unprognostic (1.05e-4)" "unprognostic (5.37e-2)" "unprognostic (1.52e-1)" "unprognostic (8.91e-2)" "unprognostic (9.78e-2)" 0.3 0.1 4.5 0.4 7.7 1.8 0.5 4.8 6.7 0.1 2.4 0.5 0.2 0.4 1.6 3.4 3.1 0.1 0.1 5.2 5.1 0.3 0.1 0.2 0.7 7.0 6.1 0.2 0.4 0.0 1.1 3.3 7.0 0.3 0.1 8.9 3.1 0.2 0.8 0.4 0.3 0.1 4.0 0.6 0.2 2.4 6.6 2.4 0.2 0.8 0.8 0.2 0.2 14.1 8.5 2.9 6.1 5.6 0.0 0.0 13.0 0.9 0.0 4.3 4.5 14.7 0.0 0.1 0.1 0.0 11.8 12.5 2.4 0.0 2.7 0.1 0.5 15.3 17.0 0.9 0.4 18.6 10.2 0.6 0.0 5.8 0.0 2.8 0.0 26.3 30.6 12.9 3.5 0.0 20.3 7.3 0.0 9.6 12.1 10.7 2.5 7.5 0.0 0.1 1.6 4.4 0.0 7.7 0.1 0.2 4.2 5.2 0.1 13.5 9.9 0.9 9.6 16.8 24.5 8.6 7.9 0.1 0.1 0.6 0.2 0.1 0.6 0.0 0.3 0.2 0.2 0.4 0.0 0.2 0.6 2.3 0.4 0.1 0.1 0.3 0.1 0.3 4.5 7.7 4.8 6.7 5.2 5.1 7.0 6.1 7.0 4.0 6.6 14.1 0.0 0.0 0.0 0.7 0.1 0.5 1.2 0.0 0.0 13.8 0.3 0.0 0.7 0.0 0.1 0.0 25.0 0.8 0.0 0.0 0.0 0.0 0.8 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 6.7 0.4 0.0 0.0 0.0 0.6 0.5 0.0 0.1 1.8 1.0 0.1 3.4 0.0 6.0 9.0 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.2 7.4 0.0 0.7 1.6 2.6 0.9 1.8 0.0 0.5 0.2 0.1 0.0 0.4 MLF2 NTN4 ENSG00000089693 "Myeloid leukemia factor 2" Q15773 12 6747996-6767475 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010811, HPA010859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Plasma membrane, Cytosol" "HPA010811: AB_1079389, HPA010859: AB_1079388" "unprognostic (1.65e-1)" "unprognostic (6.55e-2)" "unprognostic (4.42e-1)" "unprognostic (9.88e-3)" "unprognostic (1.76e-1)" "unprognostic (4.19e-2)" "unprognostic (1.52e-1)" "unprognostic (4.15e-2)" "unprognostic (1.31e-1)" "unprognostic (9.11e-2)" "unprognostic (3.37e-1)" "unprognostic (6.23e-2)" "unprognostic (1.38e-1)" "unprognostic (5.83e-2)" "unprognostic (4.72e-1)" "unprognostic (8.44e-2)" "unprognostic (3.63e-1)" 121.0 199.0 214.6 67.9 225.7 123.8 109.8 206.5 243.7 119.8 215.4 161.8 106.3 148.5 85.2 168.6 120.6 68.1 181.8 234.6 219.0 163.3 298.7 107.0 66.2 208.0 205.8 116.3 111.0 158.2 145.1 79.4 205.8 142.7 74.1 78.2 131.6 96.3 192.8 144.6 117.8 93.0 205.4 101.5 135.9 97.6 211.1 78.3 114.1 129.2 71.2 135.2 117.5 223.6 222.0 354.3 179.1 294.4 159.3 157.9 283.1 216.6 230.6 318.8 286.9 353.8 195.5 163.1 55.0 265.5 228.1 173.5 220.1 295.3 220.0 274.9 239.3 115.3 174.0 200.7 176.0 128.9 143.0 151.7 240.8 255.2 209.8 257.4 140.7 152.0 152.5 61.8 247.8 320.7 165.7 197.9 554.2 236.1 141.2 102.5 160.2 134.0 310.8 247.7 111.2 224.8 188.8 303.6 203.4 385.8 89.8 186.4 133.7 191.4 279.3 213.5 299.9 80.9 98.2 208.9 259.0 102.2 231.2 259.6 120.3 461.0 82.0 109.9 80.9 85.6 63.7 78.3 134.0 97.6 66.2 75.3 528.0 76.6 129.2 231.6 69.7 115.3 214.6 225.7 206.5 243.7 234.6 219.0 208.0 205.8 205.8 205.4 211.1 223.6 106.3 38.5 30.9 19.2 77.9 136.5 149.3 230.2 261.2 110.2 157.7 156.3 71.9 92.9 108.7 110.3 41.7 264.3 92.4 120.6 279.7 169.9 12.1 64.6 70.7 86.4 100.7 74.9 36.2 125.9 213.7 100.6 91.7 74.9 84.9 84.1 71.0 168.6 147.7 80.8 32.7 138.6 197.4 57.8 70.6 13.3 114.0 78.9 103.2 13.1 138.9 142.7 39.1 19.1 23.5 153.8 124.7 107.2 108.2 202.6 219.6 324.7 58.6 63.5 52.6 77.1 131.8 96.6 80.8 193.1 125.6 427.6 70.2 138.3 145.0 174.6 MLKL FLJ34389 ENSG00000168404 "Mixed lineage kinase domain like pseudokinase" Q8NB16 16 74671855-74700960 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Transporters" Necrosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 32.1;Endothelial cells: 25.9;granulocytes: 29.1;Macrophages: 28.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA078638 Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions, Cytosol" "HPA078638: " "unprognostic (7.53e-2)" "unprognostic (1.74e-2)" "unprognostic (2.57e-1)" "prognostic favorable (2.16e-4)" "unprognostic (1.23e-1)" "unprognostic (3.07e-1)" "unprognostic (5.69e-2)" "unprognostic (3.67e-3)" "unprognostic (1.90e-1)" "unprognostic (6.64e-3)" "unprognostic (1.37e-1)" "unprognostic (2.74e-1)" "unprognostic (1.60e-3)" "unprognostic (5.30e-2)" "unprognostic (1.26e-2)" "unprognostic (1.06e-1)" "unprognostic (1.53e-3)" 20.0 7.1 8.4 20.3 8.7 30.7 12.1 8.6 12.7 9.0 9.6 11.0 11.0 6.0 2.0 15.6 8.0 11.5 10.6 7.8 8.2 15.4 9.3 25.6 15.4 10.1 9.8 3.0 9.9 1.6 3.7 9.2 9.3 8.4 11.4 0.3 13.3 4.3 3.1 4.9 14.4 7.6 9.1 36.1 10.8 1.2 10.3 6.7 8.7 3.1 13.8 12.3 11.5 9.6 13.5 24.4 0.1 0.1 6.0 12.4 0.2 17.0 14.8 15.4 22.4 13.9 26.6 0.3 19.1 14.2 13.7 21.7 4.3 24.9 5.8 8.3 0.6 18.8 17.6 16.2 4.2 12.3 18.6 8.5 2.4 16.8 5.7 9.0 37.3 21.3 2.7 2.5 11.9 22.0 7.0 24.3 2.2 29.3 30.0 13.5 1.8 23.8 22.0 10.2 1.0 0.8 13.4 8.7 7.2 0.1 6.2 12.5 41.4 7.8 4.8 7.0 11.7 11.2 40.2 3.2 13.7 42.3 3.9 21.9 36.2 45.8 11.2 22.2 15.4 8.1 12.6 12.0 18.9 6.7 6.8 10.4 48.6 3.6 23.3 1.2 17.4 16.0 8.4 8.7 8.6 12.7 7.8 8.2 10.1 9.8 9.3 9.1 10.3 9.6 32.1 3.2 10.7 1.0 9.8 3.4 6.8 3.1 7.4 0.2 3.3 3.4 3.1 2.8 5.5 1.8 0.0 0.2 9.6 8.9 1.9 4.6 3.5 1.2 1.9 25.9 1.2 3.4 0.5 5.2 0.8 7.1 15.3 1.6 29.1 0.3 16.8 1.3 16.6 1.7 0.5 10.9 0.0 18.2 7.8 5.2 0.9 28.9 7.2 11.2 16.7 0.1 11.3 1.5 5.2 4.9 9.4 0.4 18.5 2.8 5.5 0.6 2.0 0.6 0.0 3.0 3.1 0.1 0.2 13.4 2.8 0.3 16.5 0.2 9.5 7.5 MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 4.0" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.3 0.3 0.4 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MLST8 "GbetaL, GBL, Lst8, Pop3" ENSG00000167965 "MTOR associated protein, LST8 homolog" Q9BVC4 16 2204248-2209453 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 105.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019935, HPA041841" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Golgi apparatus, Cell Junctions" "CAB019935: AB_561447, HPA041841: AB_2677701" "unprognostic (2.19e-1)" "unprognostic (7.68e-2)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (3.35e-3)" "unprognostic (1.74e-1)" "unprognostic (8.17e-3)" "unprognostic (1.52e-1)" "unprognostic (5.77e-2)" "unprognostic (5.70e-3)" "unprognostic (4.62e-2)" "unprognostic (1.65e-1)" "prognostic favorable (7.60e-4)" "unprognostic (8.74e-2)" "unprognostic (1.20e-1)" "unprognostic (2.29e-1)" "unprognostic (5.48e-2)" 16.7 29.4 31.5 9.8 31.8 13.3 17.1 31.4 51.1 16.0 25.5 17.3 12.5 15.5 5.6 24.8 14.6 9.1 25.0 32.4 29.9 26.0 31.3 13.3 10.5 32.0 31.0 19.4 35.8 13.3 19.8 11.1 32.4 20.5 4.6 5.7 19.7 8.0 39.4 22.2 15.6 4.5 29.4 16.5 22.3 33.6 32.5 9.7 22.4 21.8 5.2 16.7 15.5 34.1 20.5 61.9 23.1 60.5 29.6 20.8 38.2 17.9 20.4 26.7 22.9 83.4 29.5 51.3 40.6 20.1 12.7 25.8 23.1 51.4 3.1 39.4 113.4 36.0 61.0 51.7 44.7 57.3 49.7 29.7 34.8 31.7 41.8 22.6 28.6 74.1 54.9 35.9 14.8 89.4 55.5 74.9 47.3 18.1 57.4 55.6 23.4 93.8 20.7 13.4 73.5 40.1 26.6 62.1 46.3 8.7 38.6 54.2 22.4 33.5 38.9 27.3 23.7 43.0 26.4 57.8 17.6 47.5 29.9 0.0 25.0 4.2 14.1 29.9 11.8 14.4 13.1 15.2 24.6 12.5 15.0 15.1 2.8 14.6 30.1 13.3 13.1 20.7 31.5 31.8 31.4 51.1 32.4 29.9 32.0 31.0 32.4 29.4 32.5 34.1 11.5 6.4 16.0 10.4 24.6 14.7 16.2 29.6 21.6 31.5 24.7 29.8 3.3 15.7 16.2 16.5 20.9 63.2 13.0 44.6 35.2 34.4 48.7 9.6 13.1 16.8 28.8 26.9 8.9 42.6 50.4 19.2 42.8 11.2 8.2 26.8 20.3 16.7 46.9 30.3 8.4 37.9 22.4 19.1 14.6 105.4 14.9 18.4 17.8 1.0 28.0 29.4 19.6 5.5 5.9 28.6 37.9 15.1 34.1 17.9 43.2 36.3 11.1 30.6 19.7 11.6 16.5 34.7 28.2 29.4 15.5 52.7 15.4 26.8 49.3 17.4 MMACHC "cblC, DKFZP564I122" ENSG00000132763 "Metabolism of cobalamin associated C" Q9Y4U1 1 45500300-45513382 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Oxidoreductase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 17.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 22.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027394, HPA027399, HPA027402" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA027394: AB_10601669, HPA027399: AB_10601987, HPA027402: AB_2672255" "unprognostic (3.34e-1)" "unprognostic (1.63e-1)" "unprognostic (7.03e-3)" "unprognostic (3.14e-2)" "unprognostic (4.05e-1)" "unprognostic (1.16e-2)" "unprognostic (9.04e-2)" "unprognostic (1.03e-2)" "unprognostic (1.90e-1)" "unprognostic (1.05e-2)" "unprognostic (3.88e-2)" "unprognostic (6.81e-2)" "unprognostic (2.61e-3)" "unprognostic (2.08e-3)" "unprognostic (8.83e-2)" "unprognostic (2.50e-2)" "unprognostic (2.58e-2)" 2.0 3.1 3.3 1.7 5.3 1.2 3.5 5.1 4.2 2.9 2.3 3.7 3.3 1.7 3.0 2.8 3.5 1.3 6.9 3.4 5.1 3.5 17.4 1.2 1.8 4.1 5.6 3.5 2.9 5.5 1.3 1.5 3.9 2.0 4.4 2.1 5.0 2.4 10.8 2.0 2.4 2.3 3.5 1.6 2.3 4.3 5.6 2.2 2.3 6.6 2.0 1.7 1.5 6.0 7.7 3.9 6.6 10.0 6.1 3.7 8.1 5.9 3.9 10.5 9.4 8.3 4.7 12.0 7.4 4.9 2.0 6.2 12.3 14.0 9.6 3.3 11.4 9.4 6.5 9.2 5.8 13.5 3.3 5.3 7.8 11.6 12.6 3.7 5.1 12.5 10.8 6.7 8.1 8.2 9.1 4.3 10.9 8.8 8.9 11.1 2.7 13.2 6.2 6.0 10.5 5.4 8.8 14.5 19.3 4.9 8.3 4.6 2.3 7.3 9.9 8.3 3.3 9.9 8.5 6.9 5.3 6.4 6.9 2.3 0.5 0.5 0.5 0.8 0.8 0.7 0.7 0.4 0.6 0.6 1.3 0.6 0.9 0.8 2.7 1.3 0.4 0.4 3.3 5.3 5.1 4.2 3.4 5.1 4.1 5.6 3.9 3.5 5.6 6.0 1.1 3.2 5.5 1.6 2.1 0.1 1.8 0.8 5.7 1.3 2.7 1.5 9.8 4.3 2.2 1.8 0.0 3.7 0.6 2.8 5.9 1.3 1.0 3.6 4.8 1.5 4.2 4.8 2.6 1.4 4.3 3.6 7.1 3.2 2.5 2.9 2.5 22.9 3.3 3.3 2.7 3.2 2.0 3.2 0.9 1.2 1.8 2.7 0.0 0.0 0.6 1.4 3.1 1.5 5.3 1.8 2.3 1.5 10.4 1.7 2.0 4.6 1.2 5.2 0.0 5.0 2.4 7.4 2.1 11.5 0.1 2.7 2.4 3.9 5.8 1.8 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP15 "MT2-MMP, MTMMP2, SMCP-2" ENSG00000102996 "Matrix metallopeptidase 15" P51511 16 58025754-58046901 "Cancer-related genes, Enzymes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 55.8;Distal enterocytes: 109.3;Proximal enterocytes: 67.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 93.6;Hep G2: 51.1;OE19: 44.6;SK-BR-3: 47.3;WM-115: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002611, HPA040390" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB002611: , HPA040390: AB_2676956" "unprognostic (1.76e-2)" "unprognostic (7.32e-2)" "unprognostic (2.69e-1)" "unprognostic (6.85e-2)" "unprognostic (3.09e-1)" "unprognostic (1.68e-1)" "unprognostic (6.88e-3)" "unprognostic (1.40e-1)" "unprognostic (3.02e-2)" "unprognostic (1.24e-2)" "unprognostic (4.81e-2)" "unprognostic (1.81e-1)" "prognostic favorable (8.54e-8)" "unprognostic (3.63e-2)" "unprognostic (1.36e-1)" "unprognostic (1.28e-1)" "prognostic favorable (3.08e-4)" 11.9 3.8 8.9 4.4 6.0 0.4 7.6 7.3 11.2 5.7 5.8 28.0 40.2 3.5 1.1 4.6 6.1 14.3 41.2 6.9 8.7 14.9 50.1 9.9 2.1 15.8 10.6 1.1 18.5 12.7 8.8 28.4 16.8 4.4 14.3 1.5 8.4 9.5 7.0 4.3 33.0 3.7 5.8 9.3 29.6 34.9 18.7 1.0 46.7 5.6 1.3 5.1 2.8 8.6 15.3 11.4 5.8 30.4 6.0 0.3 93.6 1.4 0.8 5.4 1.2 9.1 38.3 0.2 17.7 1.6 4.2 21.0 5.1 4.4 1.6 0.1 10.0 0.1 4.9 51.1 7.7 0.3 19.5 3.1 7.8 0.9 2.3 8.4 3.7 8.5 12.9 0.1 1.8 7.6 0.7 2.6 17.2 44.6 3.2 7.6 0.7 8.3 16.6 5.4 1.6 10.4 20.0 47.3 9.5 13.2 5.2 8.2 3.4 0.4 9.1 3.5 1.3 0.2 0.1 0.3 1.9 2.3 78.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 8.9 6.0 7.3 11.2 6.9 8.7 15.8 10.6 16.8 5.8 18.7 8.6 14.3 19.2 14.4 9.1 0.7 2.5 1.0 4.9 2.8 3.4 5.0 3.0 24.7 55.8 12.6 18.4 16.7 48.2 1.6 109.3 1.9 35.7 5.0 3.6 1.1 17.2 11.4 2.7 1.4 12.0 49.2 4.5 35.2 6.4 0.0 18.6 13.6 39.2 12.9 1.7 1.2 33.3 10.2 3.0 0.3 6.9 0.9 0.9 1.8 1.0 0.0 2.1 0.0 4.5 1.4 13.3 38.5 3.4 0.3 1.3 67.3 7.3 6.0 1.9 0.0 0.7 2.4 0.9 4.6 3.3 2.3 48.4 0.7 23.2 45.0 1.7 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Excitatory neurons: 24.6;Horizontal cells: 15.2;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.0;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.3;CACO-2: 56.0;EFO-21: 15.8;RPTEC TERT1: 24.6;U-2 OS: 17.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 3.4 1.0 6.1 0.5 5.8 0.7 0.5 40.0 8.1 0.7 3.5 0.7 2.1 1.3 0.1 0.3 2.2 0.6 0.6 6.0 5.6 7.8 0.5 4.7 0.4 4.4 5.6 0.4 5.8 0.3 3.8 0.2 5.4 1.7 0.2 2.5 0.5 4.2 0.3 1.2 1.4 2.0 2.7 0.4 0.6 0.4 7.2 0.0 0.7 0.1 0.0 0.4 0.3 4.8 0.6 36.3 0.1 0.2 0.2 0.0 1.0 1.9 2.3 3.8 2.0 56.0 9.7 0.0 15.8 2.5 1.2 0.6 8.5 0.0 1.6 0.2 0.3 1.9 1.2 0.6 0.0 0.1 0.4 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.1 0.5 0.4 0.5 0.1 0.2 13.6 0.1 2.4 0.1 0.2 0.0 24.6 0.1 14.1 9.7 2.5 0.7 0.3 2.9 0.5 0.3 0.6 7.4 17.7 1.8 0.7 0.3 0.2 0.1 1.6 0.2 1.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 6.1 5.8 40.0 8.1 6.0 5.6 4.4 5.6 5.4 2.7 7.2 4.8 0.3 16.0 1.5 5.2 0.0 0.1 0.2 0.0 0.0 3.9 0.2 0.8 0.5 8.6 1.3 1.8 0.0 0.1 0.1 0.7 5.9 8.5 0.6 0.8 0.3 1.4 0.0 0.0 24.6 0.9 0.1 0.6 0.0 0.5 0.0 0.1 0.4 0.4 0.0 15.2 38.4 0.1 0.0 0.6 0.0 0.0 0.3 0.1 1.8 10.3 0.0 0.2 0.0 12.5 12.0 1.9 0.1 0.0 0.0 0.4 2.3 11.4 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.1 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MOAP1 "MAP-1, PNMA4" ENSG00000165943 "Modulator of apoptosis 1" Q96BY2 14 93182199-93184923 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000939, HPA076948" Enhanced Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 58: Brain - Synaptic function" "Cluster 21: OE19 - Mitochondria" "Cluster 56: Bipolar cells - Visual perception" Nucleoplasm "Cell Junctions" "HPA000939: AB_1079402, HPA076948: " "unprognostic (9.40e-3)" "unprognostic (1.26e-1)" "unprognostic (1.57e-1)" "unprognostic (7.52e-2)" "unprognostic (1.21e-1)" "unprognostic (8.75e-2)" "unprognostic (1.01e-1)" "prognostic favorable (7.37e-9)" "unprognostic (1.98e-1)" "unprognostic (6.52e-2)" "unprognostic (1.05e-3)" "unprognostic (1.58e-2)" "prognostic favorable (3.15e-6)" "unprognostic (6.93e-2)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (9.27e-2)" 17.7 32.2 39.9 11.3 39.8 40.5 19.0 17.8 54.6 25.8 9.4 36.2 13.9 20.9 26.8 17.4 24.0 17.1 55.8 46.4 59.2 30.8 20.3 21.5 19.4 30.1 25.1 19.1 19.3 45.7 37.0 16.2 39.9 32.4 15.9 92.4 20.9 30.6 44.2 17.5 22.2 22.3 22.1 19.2 26.6 10.3 33.7 23.2 24.1 34.6 17.6 24.1 12.3 38.8 9.8 8.2 19.1 25.0 16.3 6.4 11.1 10.2 14.4 12.4 11.5 8.4 8.9 30.4 19.7 14.6 8.5 16.5 13.9 12.7 13.9 10.7 15.8 16.2 17.4 11.5 19.7 15.8 25.0 9.3 18.4 7.6 13.4 30.3 15.9 35.6 6.2 15.6 11.5 40.4 24.1 10.8 7.5 20.8 8.6 12.7 23.3 14.7 29.4 28.7 36.7 31.0 9.1 16.4 48.4 14.8 25.3 12.1 14.6 4.1 5.6 9.9 5.1 30.9 31.3 15.1 12.8 10.2 7.5 53.5 5.9 19.6 15.5 6.9 19.8 6.8 19.1 19.4 6.2 11.9 23.1 21.1 6.1 16.1 8.8 5.4 16.6 12.1 39.9 39.8 17.8 54.6 46.4 59.2 30.1 25.1 39.9 22.1 33.7 38.8 20.4 32.1 32.1 11.8 21.8 16.2 18.2 11.4 13.1 91.8 18.7 12.4 71.9 24.3 13.9 20.2 50.1 28.9 33.7 10.2 41.1 36.2 4.7 26.5 15.3 18.2 48.5 9.9 37.4 15.1 5.7 16.3 12.2 60.6 27.8 36.0 16.8 8.2 16.5 84.1 35.0 21.0 34.6 13.7 9.8 1.7 17.7 15.9 12.4 12.2 16.1 85.4 50.4 18.1 16.3 22.3 7.5 27.4 15.8 21.2 15.7 19.4 7.5 96.0 19.7 15.5 21.8 27.9 22.2 10.5 15.5 47.7 28.2 23.7 16.2 23.9 MPHOSPH8 "HSMPP8, mpp8" ENSG00000196199 "M-phase phosphoprotein 8" Q99549 13 19633659-19673441 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039701, HPA040035" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA039701: AB_10805484, HPA040035: AB_10794207" "unprognostic (4.22e-1)" "unprognostic (5.58e-2)" "unprognostic (2.66e-1)" "unprognostic (4.01e-3)" "unprognostic (3.05e-2)" "unprognostic (1.86e-1)" "unprognostic (2.81e-3)" "unprognostic (4.90e-2)" "unprognostic (4.55e-2)" "unprognostic (1.59e-1)" "unprognostic (3.52e-3)" "unprognostic (3.40e-2)" "unprognostic (6.49e-2)" "unprognostic (3.86e-2)" "unprognostic (4.93e-2)" "unprognostic (2.10e-1)" "unprognostic (1.02e-1)" 29.0 32.5 32.4 30.0 31.9 27.9 28.7 36.5 48.7 38.6 31.1 39.7 22.5 36.1 31.6 23.3 34.0 23.4 36.1 31.6 40.2 22.9 21.1 28.7 39.2 31.8 35.7 51.4 28.2 26.3 31.6 25.4 31.5 31.2 24.4 36.9 32.3 31.2 23.4 33.6 33.3 26.6 26.8 39.9 28.3 21.5 33.6 23.2 32.9 18.5 26.4 32.3 31.7 36.5 26.0 16.4 23.9 39.0 30.3 38.2 42.2 38.2 27.5 23.6 20.1 25.1 44.5 40.8 29.7 23.1 36.6 42.2 44.4 26.7 30.2 51.1 22.7 65.7 27.8 30.8 27.0 47.8 51.4 22.8 33.8 18.6 26.1 35.8 31.6 32.5 32.5 25.5 22.2 25.1 36.8 39.9 23.4 48.0 18.1 29.3 55.2 32.6 40.7 19.8 32.7 20.0 35.7 32.3 35.3 39.8 19.7 39.1 37.3 18.1 16.4 34.8 19.6 17.2 19.2 40.1 13.8 43.4 28.7 133.6 23.4 42.5 31.5 18.2 28.1 64.3 35.6 31.1 11.4 54.1 42.5 34.8 69.2 30.4 27.8 35.8 30.9 9.9 32.4 31.9 36.5 48.7 31.6 40.2 31.8 35.7 31.5 26.8 33.6 36.5 117.3 93.0 110.6 42.1 129.7 69.0 102.1 99.0 97.3 201.0 74.8 95.0 94.4 110.1 92.2 103.0 83.4 151.1 132.0 95.1 49.0 57.6 84.3 82.3 129.2 109.0 58.8 78.9 94.7 54.6 83.7 118.8 62.7 118.8 144.2 101.0 133.2 81.3 72.9 210.3 89.4 113.2 67.1 74.5 55.5 37.9 179.3 71.4 67.6 51.5 99.8 114.9 166.9 56.3 78.7 48.2 99.7 157.2 118.5 80.8 100.5 61.6 66.6 219.0 177.5 111.5 118.5 211.0 203.7 57.9 74.0 58.7 142.7 105.3 86.8 65.3 MPHOSPH9 MPP9 ENSG00000051825 "M-phase phosphoprotein 9" Q99550 12 123152320-123244014 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 87.7;Inhibitory neurons: 84.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037485 Approved Uncertain "Nucleoplasm,Golgi apparatus,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "Nucleoplasm, Golgi apparatus, Centrosome" "HPA037485: AB_10672792" "unprognostic (2.98e-2)" "unprognostic (5.00e-1)" "unprognostic (4.36e-3)" "unprognostic (1.45e-2)" "unprognostic (1.62e-1)" "unprognostic (2.81e-1)" "unprognostic (5.81e-3)" "unprognostic (1.64e-1)" "unprognostic (1.58e-2)" "unprognostic (1.88e-1)" "unprognostic (8.34e-2)" "unprognostic (1.08e-2)" "unprognostic (6.53e-3)" "unprognostic (1.31e-2)" "unprognostic (2.75e-1)" "unprognostic (5.14e-3)" "unprognostic (1.17e-1)" 4.6 5.4 13.7 8.0 15.2 26.2 5.0 21.6 19.8 4.7 18.9 6.1 6.8 5.3 11.1 3.1 5.3 3.6 5.6 14.3 13.2 6.2 9.6 3.9 12.1 13.8 13.7 4.5 4.0 8.9 4.4 5.2 13.9 4.6 6.8 21.3 5.5 4.4 6.8 5.0 5.2 5.2 13.4 8.1 5.1 12.4 14.4 32.8 5.2 7.8 10.3 4.2 1.9 16.0 15.0 15.9 23.9 28.0 10.7 10.1 9.1 15.7 7.8 18.7 15.2 15.1 7.2 29.6 10.6 10.1 15.7 10.2 30.3 11.1 26.0 17.6 20.7 30.5 17.9 15.0 6.6 27.0 24.6 10.5 4.7 18.2 16.1 15.6 19.5 40.1 21.4 12.7 17.3 12.9 32.6 44.6 17.1 9.4 17.2 27.6 24.9 19.1 14.7 14.8 31.4 15.0 23.7 9.3 15.4 22.4 17.5 21.2 11.1 15.3 21.5 17.5 22.1 19.0 33.8 24.4 12.2 26.4 32.4 11.5 3.7 5.4 10.1 3.7 7.2 6.5 8.4 9.5 3.7 6.0 11.6 12.0 0.8 10.1 3.3 5.3 7.8 2.8 13.7 15.2 21.6 19.8 14.3 13.2 13.8 13.7 13.9 13.4 14.4 16.0 7.3 9.6 9.5 50.3 15.6 4.5 4.5 5.7 8.6 43.5 5.8 5.2 16.3 10.0 7.2 7.3 114.7 12.2 25.3 2.8 5.9 4.8 57.9 21.2 12.4 8.5 14.3 33.6 87.7 1.8 7.1 10.6 5.1 6.5 2.5 23.6 7.9 31.1 8.6 53.8 84.7 5.6 6.1 15.3 7.4 73.3 7.2 10.4 3.6 24.4 17.0 14.7 32.0 46.3 48.1 1.8 1.6 11.3 21.4 3.0 4.3 11.0 14.9 65.9 0.0 11.6 7.2 31.7 20.4 8.4 2.3 1.6 26.8 17.2 9.8 2.7 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPIG6B "C6orf25, G6b, G6b-B, NG31" ENSG00000204420 "Megakaryocyte and platelet inhibitory receptor G6b" O95866 6 31718594-31726714 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Heparin-binding, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 4.8;skin 1: 8.3" "Cell type enriched" "Detected in single" 14 "granulocytes: 10.1" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "NK-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in single" 14 "HEL: 6.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA054404, HPA073017" Approved "Nucleoplasm,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 330000 "Cluster 15: NK-cells - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 36: HEL - Hemostasis" "Cluster 60: Granulocytes - Receptor signaling" "Golgi apparatus" "Nucleoplasm, Endoplasmic reticulum, Plasma membrane, Cytosol" "HPA054404: , HPA073017: AB_2686566" "unprognostic (1.45e-1)" "unprognostic (1.25e-1)" "unprognostic (2.93e-1)" "unprognostic (1.77e-2)" "unprognostic (1.23e-1)" "unprognostic (6.53e-2)" "unprognostic (3.53e-2)" "unprognostic (2.71e-2)" "unprognostic (1.19e-1)" "unprognostic (1.43e-2)" "unprognostic (2.70e-1)" "unprognostic (1.71e-2)" "unprognostic (1.82e-2)" "unprognostic (1.02e-1)" "unprognostic (1.34e-1)" "unprognostic (2.55e-2)" "unprognostic (1.71e-2)" 0.5 0.0 0.0 0.1 0.0 1.1 0.4 0.1 0.2 1.0 0.1 0.3 0.1 0.4 0.0 1.6 0.5 0.2 0.8 0.1 0.1 0.1 0.3 3.5 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.6 0.0 0.2 8.3 0.4 0.0 0.0 4.8 0.3 2.3 0.1 0.0 0.5 0.0 0.0 0.5 1.3 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.8 0.0 2.2 0.0 0.0 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPP1 "DXS552E, PEMP" ENSG00000130830 "Membrane palmitoylated protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 116.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.9;Erythroid cells: 393.8;Hofbauer cells: 291.9;Macrophages: 155.9;Syncytiotrophoblasts: 454.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 215.7;neutrophil: 202.1" "Group enriched" "Detected in all" 8 "dendritic cells: 57.7;granulocytes: 215.7;monocytes: 98.8" "Cell line enhanced" "Detected in many" "HEL: 218.0;REH: 136.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 650000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (2.15e-1)" "unprognostic (4.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.83e-3)" "unprognostic (7.14e-2)" "unprognostic (2.60e-2)" "unprognostic (7.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (7.79e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-3)" "prognostic favorable (4.60e-6)" "unprognostic (6.69e-2)" "unprognostic (2.53e-2)" "unprognostic (4.68e-2)" "unprognostic (6.67e-3)" 24.1 27.2 21.0 27.1 22.0 116.8 16.5 26.2 29.7 11.6 18.6 17.2 59.4 13.4 5.3 10.5 15.7 24.3 26.0 22.5 25.2 42.9 37.5 28.3 24.9 28.3 21.9 10.6 34.6 30.7 9.7 86.5 30.7 15.5 17.6 10.6 23.7 18.1 29.2 10.2 47.3 19.7 22.5 40.9 11.8 7.1 27.3 72.8 14.0 27.2 12.5 21.3 10.0 28.2 41.4 8.3 18.7 18.7 19.0 20.1 59.5 15.3 23.3 25.3 30.8 23.7 3.7 32.8 29.3 17.1 67.9 4.6 21.6 6.9 19.9 34.9 38.0 218.0 5.7 25.3 28.6 44.4 121.4 19.4 9.0 28.2 7.0 25.9 58.5 42.1 96.1 5.3 28.7 0.2 102.6 60.3 1.9 3.8 28.2 136.0 4.8 15.5 14.8 3.3 4.7 7.5 12.7 1.2 13.3 18.5 3.2 25.8 26.6 23.2 12.5 51.8 41.7 36.6 52.9 12.5 32.7 61.7 11.1 49.7 95.6 215.7 5.1 76.6 6.0 7.8 5.9 5.7 57.7 2.7 15.4 7.9 202.1 10.1 98.8 15.5 3.5 79.1 21.0 22.0 26.2 29.7 22.5 25.2 28.3 21.9 30.7 22.5 27.3 28.2 18.3 3.2 11.2 8.1 6.3 8.7 4.8 0.2 8.0 10.2 7.1 5.1 17.0 41.5 6.2 7.3 4.2 410.9 6.9 16.3 21.5 11.7 0.6 3.5 5.7 18.9 11.5 393.8 16.1 2.8 27.0 11.4 1.1 6.4 90.6 9.6 11.7 10.6 291.9 16.8 17.1 4.4 0.0 104.7 30.2 2.4 8.7 155.9 10.6 15.9 52.5 15.4 9.2 6.0 5.9 3.7 4.1 13.2 8.1 3.1 57.4 66.3 2.2 8.2 0.0 8.6 10.3 0.7 6.8 6.4 6.0 454.4 9.9 14.5 5.8 1.2 MPP5 "FLJ12615, PALS1" ENSG00000072415 "Membrane palmitoylated protein 5" Q8N3R9 14 67240713-67336061 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 129.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A-431: 156.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000993, HPA063890" Enhanced Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA000993: AB_1079407, HPA063890: AB_2732707" "unprognostic (3.65e-1)" "unprognostic (3.82e-3)" "unprognostic (4.56e-2)" "unprognostic (9.20e-2)" "unprognostic (9.86e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.48e-1)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.93e-3)" "unprognostic (9.89e-3)" "prognostic favorable (1.71e-12)" "unprognostic (2.28e-1)" "unprognostic (1.82e-1)" "unprognostic (6.90e-2)" "unprognostic (6.87e-2)" 7.4 8.7 13.9 6.3 20.9 5.6 10.6 17.6 16.5 8.8 26.6 12.7 20.4 6.3 21.1 13.6 7.3 7.9 7.4 11.9 17.4 31.4 19.6 12.3 4.8 18.2 18.2 6.1 8.7 19.6 7.2 9.8 18.3 16.2 12.0 17.2 18.4 12.7 18.0 8.4 20.7 7.2 18.1 6.6 9.4 8.8 17.5 10.3 25.1 13.6 6.1 9.0 8.4 27.5 156.4 24.4 24.1 18.5 13.3 12.3 20.6 46.4 23.6 33.2 21.6 23.8 45.9 12.7 21.5 37.8 11.0 31.0 13.9 26.1 50.2 5.5 9.5 11.8 23.6 16.8 15.5 4.5 8.5 13.1 10.0 17.9 23.7 24.2 19.0 13.5 12.6 4.7 53.9 20.4 14.4 5.0 7.7 22.2 16.2 12.2 37.1 15.2 30.1 36.8 13.2 9.4 28.2 27.0 15.5 21.1 28.6 9.2 29.2 41.4 87.2 13.8 19.9 7.8 7.6 19.3 27.2 10.1 14.7 0.1 0.5 0.8 0.4 1.0 0.3 1.1 0.5 0.6 0.8 0.4 1.1 0.6 0.0 2.2 0.7 0.6 0.3 0.4 13.9 20.9 17.6 16.5 11.9 17.4 18.2 18.2 18.3 18.1 17.5 27.5 13.2 64.1 28.9 37.2 8.8 21.0 26.0 14.6 22.2 8.5 22.4 12.8 24.7 11.5 21.1 22.0 43.8 23.1 5.2 47.2 13.7 21.7 5.9 29.5 15.0 17.7 5.4 6.7 24.8 26.9 11.3 17.3 18.3 46.2 5.1 15.8 17.2 20.7 17.6 3.3 34.7 21.2 12.2 11.9 13.4 4.5 8.1 9.2 3.6 22.5 6.6 23.4 3.1 41.2 129.8 26.7 32.5 11.3 13.1 30.1 54.3 33.5 14.9 34.3 6.6 17.7 22.2 22.4 36.1 29.2 17.3 17.5 7.7 7.5 22.4 38.7 MPP7 FLJ32798 ENSG00000150054 "Membrane palmitoylated protein 7" Q5T2T1 10 28050993-28334486 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 37.1" "Cell type enhanced" "Detected in many" "Early spermatids: 82.3;Excitatory neurons: 76.7;Suprabasal keratinocytes: 61.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 23.3;CACO-2: 45.2;CAPAN-2: 27.9;T-47d: 89.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037597, HPA037598" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" Nucleoplasm "HPA037597: AB_2675569, HPA037598: AB_10696941" "unprognostic (1.12e-1)" "unprognostic (1.24e-1)" "unprognostic (1.59e-3)" "unprognostic (1.49e-1)" "unprognostic (6.64e-2)" "unprognostic (7.78e-2)" "unprognostic (9.31e-3)" "prognostic favorable (5.88e-4)" "unprognostic (2.15e-1)" "unprognostic (1.70e-1)" "unprognostic (1.88e-1)" "unprognostic (2.26e-1)" "prognostic favorable (2.79e-14)" "unprognostic (2.46e-1)" "unprognostic (1.88e-1)" "unprognostic (4.66e-2)" "unprognostic (1.03e-2)" 3.8 2.7 0.1 5.7 1.0 8.8 9.7 4.7 2.2 6.4 0.1 10.7 6.0 5.1 1.9 37.1 11.8 6.4 6.6 0.4 0.0 12.2 1.9 10.1 2.6 0.0 0.0 3.4 12.1 11.8 2.2 11.7 0.1 8.0 9.3 9.7 7.6 4.8 13.8 24.8 7.2 8.7 0.0 2.4 8.8 9.0 0.0 3.2 14.4 14.3 6.9 9.7 9.6 1.1 5.9 0.1 0.6 0.0 0.1 0.1 23.3 1.2 0.9 4.7 7.4 45.2 27.9 0.0 0.3 3.4 3.4 10.4 3.9 7.5 10.9 0.0 7.5 0.0 1.3 2.8 0.0 0.0 0.0 0.3 11.6 0.7 0.4 0.0 0.0 2.2 1.1 0.0 6.2 10.9 2.3 0.0 1.4 8.9 2.1 1.2 13.3 0.0 0.4 19.0 1.1 0.0 2.3 11.3 0.0 3.6 89.3 1.1 0.0 1.8 12.5 0.0 1.0 0.2 0.0 0.1 0.1 10.7 0.0 0.0 7.7 9.0 3.8 2.5 5.6 0.6 4.2 2.6 7.8 0.5 7.9 5.7 3.1 5.0 1.5 0.1 1.1 5.1 0.1 1.0 4.7 2.2 0.4 0.0 0.0 0.0 0.1 0.0 0.0 1.1 1.6 44.8 48.3 10.4 5.5 23.1 10.9 9.5 7.4 1.1 14.7 8.6 12.1 10.0 24.3 14.7 16.7 50.0 9.8 15.3 9.8 5.5 82.3 9.3 0.6 11.7 6.7 4.2 76.7 12.9 3.5 2.6 11.2 6.6 1.3 0.7 2.9 3.2 5.4 3.3 30.3 10.4 8.2 4.7 5.3 20.3 0.9 8.1 7.2 12.2 16.2 24.0 4.1 4.5 2.5 6.6 7.8 0.4 5.1 7.5 12.1 9.5 19.3 8.5 0.0 1.5 7.6 5.4 9.5 48.0 61.1 46.5 16.3 0.1 11.3 17.4 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MPZL2 "EVA, EVA1" ENSG00000149573 "Myelin protein zero like 2" O60487 11 118253416-118264536 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 222.5;urinary bladder: 155.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 332.5;Basal prostatic cells: 504.4;Basal respiratory cells: 289.1;Squamous epithelial cells: 336.4;Suprabasal keratinocytes: 467.4;Urothelial cells: 489.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 11.6;intermediate monocyte: 9.2;myeloid DC: 17.0;neutrophil: 13.2" "Group enriched" "Detected in many" 10 "dendritic cells: 17.0;granulocytes: 13.2;monocytes: 11.6" "Cell line enhanced" "Detected in some" "CAPAN-2: 120.9;EFO-21: 130.4;HaCaT: 166.9;RT4: 321.7;TIME: 351.9" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 38.8" HPA060740 Approved Approved "Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "HPA060740: AB_2684352" "unprognostic (1.74e-1)" "unprognostic (6.02e-2)" "unprognostic (8.23e-2)" "unprognostic (3.28e-3)" "unprognostic (9.95e-3)" "unprognostic (1.56e-1)" "unprognostic (2.11e-3)" "unprognostic (3.58e-1)" "unprognostic (7.39e-2)" "unprognostic (5.45e-2)" "prognostic unfavorable (1.14e-4)" "unprognostic (1.91e-1)" "unprognostic (3.91e-2)" "unprognostic (3.07e-2)" "unprognostic (1.80e-1)" "prognostic favorable (1.62e-4)" "unprognostic (2.08e-2)" 28.6 4.7 2.5 11.9 2.1 0.7 19.6 2.3 4.8 56.7 5.2 31.1 17.0 16.9 38.5 222.5 46.4 33.5 7.2 2.3 2.6 26.4 23.2 47.0 2.3 3.2 3.0 3.8 13.5 27.1 10.7 1.7 3.2 48.6 30.8 0.9 58.0 69.5 4.7 38.8 11.3 14.7 3.6 4.6 37.0 0.9 3.4 18.1 30.3 1.0 52.6 155.9 120.5 2.8 65.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 27.0 120.9 0.3 130.4 0.0 0.6 166.9 0.0 38.9 0.0 0.2 9.5 0.1 1.7 35.8 0.0 0.0 0.4 0.0 90.2 0.0 3.0 0.0 86.8 0.8 0.0 0.2 0.0 51.3 0.2 0.2 1.6 34.2 0.1 0.0 0.0 6.4 14.9 321.7 0.1 0.0 5.8 61.4 0.0 0.5 26.1 0.7 351.9 0.1 0.2 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 2.3 11.6 3.0 0.1 9.2 1.3 0.0 0.6 0.4 17.0 0.0 0.8 0.9 13.2 0.4 1.4 0.3 0.2 3.8 2.5 2.1 2.3 4.8 2.3 2.6 3.2 3.0 3.2 3.6 3.4 2.8 5.9 83.3 123.3 0.0 0.2 332.5 504.4 289.1 127.5 0.0 29.0 17.4 3.4 30.0 221.1 128.8 0.0 1.7 0.5 52.0 0.0 39.4 0.0 91.6 18.8 33.6 5.3 3.6 0.0 51.1 0.2 8.2 29.6 194.0 7.0 0.0 45.3 16.5 0.8 0.0 0.0 6.3 81.4 6.4 27.0 0.3 0.0 7.8 21.4 1.9 4.9 0.0 1.0 0.0 0.0 68.2 20.8 0.0 1.2 186.3 3.3 6.9 65.2 0.0 0.0 0.3 9.2 0.2 0.7 336.4 467.4 17.8 5.4 0.0 33.4 489.7 MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033425-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" 8.6 9.6 3.2 14.2 3.3 11.1 9.7 2.2 3.5 10.2 5.8 6.7 7.4 9.5 9.6 9.6 10.4 12.7 6.2 3.1 3.8 9.9 10.6 18.0 14.6 4.7 3.3 13.6 3.7 14.0 8.9 13.5 3.7 10.9 8.1 1.5 5.9 10.5 2.1 8.7 6.9 12.5 3.8 12.3 8.7 2.6 4.4 20.2 16.7 3.8 15.2 16.3 7.4 4.8 7.9 5.4 0.1 4.6 32.2 38.8 13.9 15.5 42.2 12.7 21.5 2.2 31.9 9.7 31.6 28.1 9.9 20.5 0.7 18.3 11.1 29.6 5.2 14.2 5.6 9.8 10.8 11.5 40.6 25.2 49.6 18.9 20.3 23.7 1.3 17.8 26.7 25.6 24.9 8.8 12.1 8.3 0.1 0.1 0.8 13.7 0.3 27.3 13.9 23.1 0.2 0.3 8.2 14.8 10.9 6.0 15.4 24.6 8.1 12.5 1.7 21.8 7.7 42.2 15.3 17.9 11.7 14.7 1.2 32.6 21.8 22.9 16.3 27.4 14.6 14.3 14.6 14.6 18.8 18.3 10.8 16.2 14.7 19.0 23.6 10.2 17.0 15.2 3.2 3.3 2.2 3.5 3.1 3.8 4.7 3.3 3.7 3.8 4.4 4.8 4.4 19.2 32.4 8.8 14.7 5.0 8.3 32.6 12.0 0.8 7.7 6.1 4.1 8.6 20.9 14.7 0.0 17.5 15.9 1.6 5.9 10.8 0.3 5.9 12.1 4.9 2.4 11.4 3.1 6.4 9.5 12.8 2.6 7.3 17.1 13.5 3.6 8.9 25.8 0.0 1.7 2.7 32.6 25.2 9.1 0.4 10.8 25.3 7.2 11.2 30.8 4.1 26.8 0.0 0.5 7.5 4.5 12.0 9.1 7.4 2.2 2.4 15.3 0.6 0.0 8.6 9.2 0.4 1.6 10.9 5.4 24.5 15.7 22.4 3.5 13.4 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MRNIP "C5orf45, DKFZp686L2452, LOC51149, MGC65027, MGC78537" ENSG00000161010 "MRN complex interacting protein" Q6NTE8 5 179835133-179862173 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Endometrial ciliated cells: 49.7;Glandular and luminal cells: 31.3;Respiratory ciliated cells: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043975 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA043975: AB_2678754" "unprognostic (4.97e-2)" "unprognostic (2.79e-1)" "unprognostic (7.98e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (5.15e-3)" "unprognostic (1.68e-3)" "unprognostic (2.51e-2)" "unprognostic (1.10e-1)" "unprognostic (6.11e-2)" "unprognostic (3.63e-3)" "unprognostic (2.05e-2)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.18e-1)" "unprognostic (3.73e-1)" "unprognostic (7.00e-2)" "unprognostic (1.43e-3)" 7.8 7.2 10.5 3.5 10.6 1.4 9.5 13.1 12.9 21.8 11.5 12.3 2.5 11.4 5.9 6.4 16.7 2.2 7.1 10.6 10.3 13.1 10.0 8.9 5.5 10.8 10.6 21.0 10.3 5.2 19.2 1.5 10.8 15.4 2.8 3.0 9.9 7.1 5.4 7.9 17.1 3.8 10.0 19.0 8.8 10.1 10.6 2.7 15.5 2.7 5.3 12.7 13.7 11.8 1.0 1.9 3.5 8.4 7.4 6.6 4.0 2.5 2.3 3.2 4.8 2.5 3.2 4.1 2.9 1.3 1.4 2.6 4.4 8.3 2.6 3.7 3.5 1.3 4.3 2.1 4.6 1.7 1.6 4.9 7.0 3.7 3.0 2.4 3.6 4.1 2.0 1.8 3.5 3.9 2.8 1.7 1.7 1.3 1.9 3.3 1.4 3.2 5.7 0.8 6.6 2.1 1.2 3.3 3.1 2.6 4.1 1.4 0.7 1.8 1.4 1.4 1.5 2.2 1.4 2.9 1.7 2.7 1.3 1.5 0.6 2.9 2.7 0.7 3.8 8.0 4.0 3.2 0.8 10.2 6.4 4.5 0.9 3.5 0.9 4.9 2.6 1.9 10.5 10.6 13.1 12.9 10.6 10.3 10.8 10.6 10.8 10.0 10.6 11.8 22.4 16.0 15.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 13.7 21.1 0.0 0.0 11.8 18.4 0.0 10.5 11.6 0.0 46.9 5.1 0.0 49.7 19.0 5.8 0.0 0.0 0.0 2.2 6.8 9.7 0.0 31.3 11.4 20.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 3.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.0 0.0 0.0 14.5 29.9 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 9.3 7.6 18.4 0.0 0.0 MRPL42 "HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31" ENSG00000198015 "Mitochondrial ribosomal protein L42" Q9Y6G3 12 93467514-93516214 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 397.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039398 Approved Supported "Plasma membrane,Mitochondria" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Mitochondria" "HPA039398: AB_10673529" "unprognostic (9.32e-2)" "unprognostic (4.18e-2)" "unprognostic (4.50e-2)" "unprognostic (3.89e-2)" "unprognostic (1.27e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.49e-4)" "unprognostic (6.13e-2)" "unprognostic (3.66e-2)" "unprognostic (1.95e-1)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (4.92e-1)" "unprognostic (1.62e-1)" "prognostic favorable (8.12e-4)" 15.7 26.7 6.8 8.8 8.3 13.9 14.9 11.6 9.0 15.7 9.9 16.9 13.5 14.5 10.9 19.3 14.2 8.1 17.2 7.9 9.8 21.4 20.4 12.8 12.2 7.5 8.3 14.3 13.8 23.4 15.4 11.3 8.6 15.9 16.8 6.1 14.0 10.5 12.0 14.9 13.5 13.8 6.3 10.8 15.9 14.4 7.7 19.2 14.0 14.4 14.9 16.6 16.6 11.7 30.5 42.3 53.5 33.8 25.5 36.8 36.5 43.0 33.0 45.4 32.9 51.8 11.6 49.9 16.3 32.1 29.8 22.4 61.5 48.0 74.3 50.6 40.5 45.0 26.8 61.9 41.9 74.0 21.3 31.0 44.4 48.4 60.5 42.2 46.5 53.0 61.3 19.0 54.0 36.1 67.2 49.3 65.1 52.8 55.9 48.1 25.5 40.4 49.2 77.0 39.8 32.0 36.0 39.3 41.3 42.0 35.5 33.4 29.1 26.5 22.1 21.3 49.6 31.2 49.0 46.1 12.2 45.7 41.5 21.0 14.4 20.4 14.7 21.2 18.9 25.9 19.4 16.6 16.4 23.7 21.3 21.8 8.3 27.0 20.4 11.2 28.1 16.3 6.8 8.3 11.6 9.0 7.9 9.8 7.5 8.3 8.6 6.3 7.7 11.7 55.0 28.9 35.5 13.4 59.9 67.3 97.6 131.6 50.1 34.9 48.7 38.1 82.6 42.9 82.5 46.0 60.5 96.7 41.4 38.2 213.2 86.2 397.6 87.5 61.3 48.7 93.2 66.7 16.2 77.4 133.1 54.5 48.9 48.6 58.4 50.7 32.9 48.4 54.0 47.1 22.1 66.8 107.8 34.1 47.9 165.0 51.6 32.6 60.5 6.5 35.2 22.1 54.6 20.1 20.3 89.8 49.9 56.1 59.8 109.8 44.9 146.5 96.7 41.6 52.6 42.3 59.8 230.5 66.6 59.7 75.0 95.5 51.7 100.1 82.1 115.4 MRPL44 "FLJ12701, FLJ13990" ENSG00000135900 "Mitochondrial ribosomal protein L44" Q9H9J2 2 223957463-223967714 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Ribosomal proteins" "Endonuclease, Hydrolase, Nuclease, Ribonucleoprotein, Ribosomal protein, RNA-binding" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038147, HPA038148" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Mitochondria" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" Mitochondria "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA038147: AB_10671521, HPA038148: AB_2675863" "unprognostic (5.21e-2)" "unprognostic (3.48e-1)" "unprognostic (3.38e-2)" "unprognostic (3.00e-1)" "unprognostic (7.05e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (2.16e-2)" "unprognostic (3.32e-1)" "unprognostic (7.65e-2)" "unprognostic (8.33e-2)" "unprognostic (6.65e-2)" "prognostic favorable (2.02e-4)" "unprognostic (2.47e-2)" "unprognostic (1.14e-1)" "unprognostic (9.93e-2)" "unprognostic (2.49e-1)" 16.2 26.9 16.2 14.9 17.4 45.4 17.6 17.1 20.3 12.9 19.0 21.8 19.3 12.7 13.2 18.0 16.3 17.5 33.8 17.1 18.8 37.4 39.3 12.5 32.5 16.2 16.1 15.2 17.4 19.7 11.6 20.0 16.8 15.3 22.9 10.0 16.1 13.2 42.6 15.7 17.9 14.4 17.5 17.8 16.2 18.2 17.8 21.4 16.2 40.6 26.5 17.1 11.5 17.9 27.3 22.6 33.1 38.3 30.6 36.1 52.4 30.0 33.6 48.0 50.4 81.0 33.4 41.1 31.9 26.0 43.9 35.3 54.5 41.5 44.1 39.0 38.7 45.0 24.0 64.4 44.9 50.0 33.1 42.5 50.9 29.1 38.7 40.4 47.8 41.4 43.7 31.6 38.9 31.9 37.8 62.9 49.4 54.8 23.6 43.8 40.6 25.5 64.3 22.8 45.0 25.7 22.0 49.0 74.8 48.6 41.4 71.2 31.5 31.8 24.7 27.3 24.5 34.5 25.9 58.7 32.2 47.4 35.6 55.7 44.5 35.3 28.5 44.8 36.5 45.9 30.4 34.4 42.2 42.3 36.5 32.3 58.1 33.8 41.2 33.9 33.7 36.3 16.2 17.4 17.1 20.3 17.1 18.8 16.2 16.1 16.8 17.5 17.8 17.9 11.7 6.4 13.1 3.9 31.3 17.8 27.4 52.6 23.9 17.3 15.6 17.4 10.4 27.1 30.0 27.6 0.0 95.3 29.5 25.0 82.2 45.3 8.1 17.1 22.3 20.7 13.1 26.5 6.5 35.1 64.8 24.9 14.3 26.6 18.4 22.0 20.7 51.5 46.6 11.8 6.9 22.0 48.8 33.3 14.5 7.9 18.0 25.4 33.8 4.7 35.3 16.5 20.6 7.5 9.7 37.2 18.1 18.0 24.8 21.7 23.6 106.1 25.6 12.7 19.7 14.2 18.8 41.1 56.3 22.8 16.6 48.7 20.9 40.9 28.3 37.6 MRPL46 "C15orf4, LIECG2, P2ECSL" ENSG00000259494 "Mitochondrial ribosomal protein L46" Q9H2W6 15 88459477-88467390 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 119.3;Proximal tubular cells: 133.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050166, HPA076046" Approved Supported "Nucleoplasm,Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 39: CACO-2 - Unknown function" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Cell Junctions" "HPA050166: AB_2681039, HPA076046: " "unprognostic (1.42e-1)" "unprognostic (6.94e-3)" "unprognostic (1.02e-1)" "unprognostic (1.21e-2)" "unprognostic (3.28e-2)" "unprognostic (5.16e-2)" "unprognostic (6.22e-2)" "unprognostic (1.84e-1)" "unprognostic (1.79e-1)" "unprognostic (4.64e-3)" "unprognostic (7.78e-2)" "unprognostic (5.65e-2)" "prognostic favorable (2.09e-6)" "unprognostic (7.73e-2)" "unprognostic (9.18e-2)" "unprognostic (6.96e-3)" "unprognostic (1.63e-1)" 25.1 51.5 20.3 12.9 21.7 11.3 22.7 23.7 25.4 14.6 22.0 24.2 20.0 17.1 18.2 26.4 17.1 13.0 76.1 20.8 23.6 34.7 70.9 12.7 20.9 23.1 22.1 17.2 16.2 24.6 16.2 19.6 23.6 14.9 23.6 16.8 17.1 15.2 73.3 17.9 19.7 18.4 21.7 19.1 24.8 28.1 22.7 18.9 17.2 84.6 20.3 20.7 16.2 22.6 27.8 87.2 27.2 29.8 38.0 28.6 51.5 38.6 35.5 56.9 50.4 108.6 59.3 64.9 38.6 34.9 51.0 65.9 107.4 47.4 44.8 26.3 86.4 53.6 61.5 114.3 24.6 54.2 40.4 32.7 56.6 42.8 28.7 29.0 50.2 63.2 60.7 26.6 42.7 59.6 44.2 68.4 43.5 50.5 52.9 51.9 37.9 49.2 44.5 88.2 42.1 26.5 36.6 57.7 81.8 44.6 64.8 65.7 31.3 44.0 41.9 23.3 56.4 24.2 55.7 53.0 48.5 58.1 34.2 27.1 45.5 33.7 60.0 60.5 69.6 78.8 63.3 58.7 58.7 69.5 69.5 61.6 7.9 62.9 45.0 50.5 68.0 61.5 20.3 21.7 23.7 25.4 20.8 23.6 23.1 22.1 23.6 21.7 22.7 22.6 18.9 0.0 10.3 5.2 21.0 13.8 22.4 59.8 9.6 21.2 17.3 21.3 70.4 37.1 32.3 36.8 27.1 94.3 10.7 20.4 119.3 35.0 67.1 20.0 16.6 18.4 28.3 17.7 4.2 38.0 42.1 19.2 19.9 19.5 22.2 25.8 17.2 105.0 35.6 15.2 5.9 20.6 44.7 13.4 5.5 16.3 14.3 10.8 7.2 3.7 42.1 25.1 20.6 4.5 6.1 31.7 18.4 18.8 17.3 21.9 32.1 133.6 26.2 28.4 26.3 19.5 25.5 55.3 27.4 27.1 23.3 80.7 18.5 66.9 36.1 29.4 MRPL58 "DS-1, ICT1" ENSG00000167862 "Mitochondrial ribosomal protein L58" Q14197 17 75012670-75021261 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Protein biosynthesis" "Hydrolase, Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 60.1;Distal tubular cells: 56.7;Ductal cells: 50.9;Exocrine glandular cells: 60.3;Hofbauer cells: 48.1;Pancreatic endocrine cells: 53.7;Proximal tubular cells: 121.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003634, HPA076987" Approved Supported "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Mitochondria "Nucleoplasm, Plasma membrane" "HPA003634: AB_1851388, HPA076987: " "unprognostic (2.04e-1)" "unprognostic (1.57e-2)" "unprognostic (1.94e-3)" "unprognostic (7.12e-2)" "unprognostic (3.16e-2)" "unprognostic (4.35e-2)" "unprognostic (1.38e-3)" "unprognostic (1.52e-1)" "unprognostic (2.57e-1)" "unprognostic (3.79e-3)" "unprognostic (4.98e-2)" "unprognostic (2.43e-2)" "prognostic unfavorable (2.09e-4)" "unprognostic (1.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.66e-2)" "unprognostic (1.71e-1)" 22.7 36.3 22.1 18.0 22.8 22.8 24.6 24.4 23.0 17.1 31.9 25.9 19.1 19.4 18.2 32.1 17.5 13.1 49.1 21.9 23.6 34.7 47.2 16.3 24.4 23.4 22.6 14.2 27.4 25.0 14.0 19.3 23.4 18.6 22.8 11.2 21.8 18.6 79.0 28.4 21.7 18.8 23.3 21.6 26.0 10.5 22.9 18.3 18.7 50.3 23.8 24.5 19.9 24.5 81.1 111.4 36.5 42.1 38.3 37.9 50.5 46.7 50.7 95.7 80.7 86.3 49.5 56.0 37.3 46.8 58.9 56.3 75.6 80.7 100.2 28.1 87.7 43.8 50.5 72.2 72.5 92.5 28.8 40.9 37.8 63.3 101.0 32.3 73.8 57.0 71.7 39.9 54.8 100.9 80.7 63.4 27.5 125.3 147.1 41.2 64.8 81.2 71.1 58.5 33.5 64.1 40.3 72.5 92.9 46.7 97.5 75.6 31.6 50.8 56.0 54.3 89.7 41.0 34.8 63.2 58.5 102.5 43.5 26.6 41.2 21.4 30.8 40.9 27.1 33.8 38.0 31.4 55.3 29.3 27.8 31.1 4.0 42.2 36.1 37.2 67.2 42.5 22.1 22.8 24.4 23.0 21.9 23.6 23.4 22.6 23.4 23.3 22.9 24.5 18.8 32.1 8.7 0.0 4.3 0.0 0.0 0.0 0.0 0.0 22.5 32.8 0.0 0.0 8.1 25.8 0.0 60.1 11.4 0.0 56.7 50.9 0.0 29.3 18.3 8.4 0.0 0.0 0.0 60.3 40.5 8.9 0.0 19.0 1.3 22.3 0.0 0.0 48.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 0.0 0.0 15.0 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.8 0.0 0.0 121.1 21.1 0.0 0.0 0.0 12.8 0.0 0.0 0.0 0.0 29.1 7.4 43.5 0.0 0.0 MRPS18B "C6orf14, HSPC183, MRPS18-2, PTD017" ENSG00000204568 "Mitochondrial ribosomal protein S18B" Q9Y676 6 30617840-30626395 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043485, HPA050334" Supported Supported "Cell Junctions,Mitochondria" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Cell Junctions" "HPA043485: AB_2678506, HPA050334: AB_2681091" "unprognostic (8.18e-3)" "unprognostic (1.14e-1)" "unprognostic (8.96e-2)" "unprognostic (2.51e-2)" "unprognostic (4.20e-2)" "unprognostic (7.40e-2)" "unprognostic (9.45e-2)" "unprognostic (1.32e-1)" "unprognostic (1.89e-1)" "unprognostic (2.98e-2)" "unprognostic (1.76e-1)" "unprognostic (1.40e-2)" "prognostic favorable (3.99e-5)" "unprognostic (1.89e-1)" "unprognostic (1.64e-1)" "unprognostic (5.14e-2)" "unprognostic (5.39e-2)" 37.2 52.0 43.6 27.6 45.7 20.3 61.0 46.8 44.3 41.1 43.2 52.3 49.8 31.3 57.6 39.3 62.5 27.4 108.1 40.5 44.1 77.9 99.8 39.4 43.6 46.0 45.2 63.0 47.0 74.0 29.2 38.4 46.2 32.0 62.3 41.6 58.0 42.4 180.2 45.1 39.4 38.1 45.2 39.3 44.4 22.0 46.1 43.7 54.1 229.0 63.6 33.0 29.4 48.2 112.7 68.3 51.1 73.5 72.9 101.8 92.6 39.8 92.6 122.8 75.5 117.7 51.8 112.6 91.5 61.7 91.3 86.1 115.0 109.9 122.0 68.7 122.9 107.9 45.1 124.2 67.2 105.7 45.4 88.8 139.4 99.5 273.8 82.7 72.4 104.7 171.3 107.7 112.2 83.1 70.6 111.4 40.6 86.1 81.8 91.2 69.8 220.7 114.8 49.5 111.3 38.4 34.7 147.1 163.0 46.0 190.6 58.4 39.6 79.2 80.8 47.3 70.8 89.5 114.1 99.2 38.3 154.6 121.7 79.2 72.4 42.5 77.0 94.4 104.7 153.5 104.3 86.3 79.8 140.3 129.6 103.5 7.2 120.3 101.4 74.3 108.1 108.4 43.6 45.7 46.8 44.3 40.5 44.1 46.0 45.2 46.2 45.2 46.1 48.2 59.4 60.9 56.1 7.2 58.4 36.8 65.9 114.0 58.6 47.4 56.6 73.0 175.5 117.2 75.0 47.8 64.6 121.2 43.7 39.1 193.7 103.8 54.2 37.5 42.8 59.4 31.3 45.4 6.0 92.1 124.9 47.4 39.3 30.8 37.4 53.1 61.8 121.6 81.4 43.7 7.9 59.5 75.3 53.2 30.4 37.4 70.2 39.7 60.5 1.9 80.0 46.9 70.0 4.5 14.4 69.5 49.9 44.8 56.8 53.2 89.6 201.6 60.4 69.4 52.6 50.0 53.0 29.6 57.4 61.7 44.9 96.5 43.9 144.4 85.3 50.1 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MS4A12 "FLJ20217, Ms4a10" ENSG00000071203 "Membrane spanning 4-domains A12" Q9NXJ0 11 60492778-60507430 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 23 "intestine: 254.3" "Cell type enriched" "Detected in some" 4 "Distal enterocytes: 1139.3" "Cancer enriched" "Detected in some" 8 "colorectal cancer: 6.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "RH-30: 1.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA048616, HPA057657" Enhanced Approved "Nucleoli,Endoplasmic reticulum,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli, Endoplasmic reticulum, Golgi apparatus" "HPA048616: , HPA057657: AB_2683491" "unprognostic (2.64e-2)" "unprognostic (2.33e-1)" "unprognostic (1.49e-1)" "unprognostic (3.26e-1)" "unprognostic (2.83e-1)" "unprognostic (9.20e-3)" 0.2 0.0 0.0 10.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 234.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 254.3 0.0 0.0 0.5 0.0 0.0 0.3 4.8 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1139.3 0.0 0.0 0.4 0.1 0.0 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 15.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 255.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.7 0.0 0.0 0.0 0.6 0.1 27.8 0.0 MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.0" "Group enriched" "Detected in some" 44 "Early spermatids: 262.3;Late spermatids: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cell line enriched" "Detected in single" 23 "THP-1: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.78e-1)" "unprognostic (1.76e-1)" "unprognostic (5.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (4.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (2.14e-1)" "unprognostic (4.50e-6)" "unprognostic (3.73e-2)" "unprognostic (7.16e-3)" "unprognostic (8.40e-2)" "unprognostic (7.11e-2)" 5.1 3.7 6.2 3.5 5.6 0.6 3.6 5.8 8.8 1.2 7.5 2.7 0.7 0.9 0.6 0.9 1.3 0.9 2.6 5.8 6.3 1.8 2.0 11.9 1.3 7.7 6.8 0.7 1.3 0.3 1.5 2.4 7.2 1.8 1.1 0.4 1.9 0.5 0.9 0.9 2.7 1.2 6.0 10.4 1.2 73.0 8.5 0.3 1.5 0.3 1.9 2.0 1.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 3.4 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.9 6.2 5.6 5.8 8.8 5.8 6.3 7.7 6.8 7.2 6.0 8.5 8.0 0.2 0.0 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 262.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.3 5.5 672.0 4.1 10.4 0.0 3.7 5.7 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.7 0.0 6.6 0.1 0.0 6.5 3.4 0.0 0.3 0.1 0.1 0.0 0.0 0.0 MS4A15 ENSG00000166961 "Membrane spanning 4-domains A15" Q8N5U1 11 60756867-60776733 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lung: 43.9" "Cell type enriched" "Detected in some" 15 "Alveolar cells type 1: 96.1" "Cancer enhanced" "Detected in many" "lung cancer: 6.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Lineage enriched" "Detected in single" 12 "T-cells: 3.2" "Cell line enhanced" "Detected in some" "EFO-21: 1.2;HEL: 3.6;JURKAT: 1.6;MOLT-4: 1.6;U-266/70: 4.0;U-266/84: 2.1" "Region enriched" "Detected in some" 28 "olfactory bulb: 166.8" "Region enriched" "Detected in single" 26 "olfactory bulb: 20.2" HPA054563 Approved "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 19: Lung - Lung function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Cytosol "HPA054563: " "unprognostic (1.85e-1)" "unprognostic (4.31e-3)" "unprognostic (8.59e-2)" "unprognostic (5.89e-4)" "unprognostic (4.49e-1)" "unprognostic (1.09e-3)" "unprognostic (3.92e-3)" "unprognostic (5.43e-3)" "unprognostic (1.20e-1)" "unprognostic (7.30e-2)" "unprognostic (3.14e-1)" "unprognostic (1.04e-9)" "unprognostic (7.02e-2)" "unprognostic (8.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-1)" 0.3 0.2 0.2 0.4 0.2 0.1 2.2 0.3 0.4 0.3 0.2 0.3 1.0 1.2 0.3 0.4 1.0 0.2 0.3 0.7 0.2 0.1 0.0 43.9 0.5 0.4 0.2 1.8 0.1 0.0 0.0 0.7 0.4 0.3 0.6 0.4 0.1 1.2 0.0 0.0 2.2 1.6 0.1 0.3 0.4 0.6 0.2 3.8 0.3 0.0 1.8 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.0 3.2 0.2 0.2 0.2 0.3 0.4 0.7 0.2 0.4 0.2 0.4 0.1 0.2 0.3 0.2 96.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MSRA ENSG00000175806 "Methionine sulfoxide reductase A" Q9UJ68 8 10054292-10428891 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 86.0;liver: 64.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 625.8;Inhibitory neurons: 318.6;Oligodendrocyte precursor cells: 268.9;Proximal tubular cells: 666.1" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in many" 5 "cerebellum: 28.4" "Immune cell enhanced" "Detected in some" "eosinophil: 5.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 12.3" "Low region specificity" "Detected in all" "HPA023804, HPA075766" Approved Supported "Nucleoplasm,Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" No No 55000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 3: HMC-1 - Innate immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Cytosol" "Plasma membrane, Actin filaments" "HPA023804: AB_1853826, HPA075766: " "unprognostic (1.55e-1)" "unprognostic (4.30e-3)" "unprognostic (1.45e-3)" "unprognostic (1.00e-2)" "unprognostic (4.21e-2)" "unprognostic (1.62e-2)" "unprognostic (1.49e-2)" "unprognostic (6.40e-2)" "unprognostic (9.69e-2)" "unprognostic (1.08e-1)" "unprognostic (1.80e-1)" "unprognostic (4.58e-2)" "unprognostic (1.07e-3)" "unprognostic (6.43e-3)" "unprognostic (4.02e-1)" "unprognostic (6.36e-3)" "unprognostic (3.07e-1)" 17.0 20.4 2.2 1.1 3.0 13.5 16.1 28.4 5.4 9.1 0.0 13.9 1.1 10.7 0.1 11.6 7.4 0.4 29.0 3.8 0.0 86.0 64.0 12.2 0.6 0.0 0.4 6.4 14.5 0.7 9.2 0.8 1.8 9.2 0.6 0.6 10.5 1.0 14.5 9.5 20.1 0.8 0.0 18.6 14.2 15.2 0.3 1.5 9.6 1.3 0.6 11.6 8.2 2.8 0.1 0.9 1.3 4.3 1.2 1.4 0.5 2.5 0.2 0.3 1.7 0.6 2.1 0.0 0.6 2.5 5.8 2.3 0.4 0.1 1.3 0.2 0.0 0.3 1.5 2.2 4.3 0.8 12.3 0.4 3.2 0.3 0.0 1.4 0.6 0.3 0.4 0.2 4.9 0.1 0.0 0.3 0.6 3.3 0.8 1.6 1.3 2.0 1.1 1.1 2.5 1.5 4.6 0.2 0.5 0.4 2.3 2.8 2.6 1.7 2.0 0.4 1.2 0.2 0.1 0.7 4.8 0.8 3.1 0.5 1.9 5.6 0.4 1.2 0.3 0.6 0.4 0.3 1.2 0.1 0.3 0.2 2.2 0.7 0.9 0.2 0.3 0.2 2.2 3.0 28.4 5.4 3.8 0.0 0.0 0.4 1.8 0.0 0.3 2.8 44.1 0.0 7.4 152.8 21.4 16.4 29.3 10.8 14.2 10.1 21.2 21.8 21.6 25.8 7.2 25.8 31.3 7.7 12.4 26.4 92.0 32.3 80.6 13.6 8.7 30.3 9.6 3.4 625.8 47.1 4.6 13.1 14.8 11.8 80.7 13.7 19.6 97.2 47.0 16.8 318.6 20.8 4.1 33.6 48.3 167.9 9.3 38.0 30.2 85.3 22.3 14.6 11.3 268.9 60.7 51.1 37.8 9.8 16.2 33.8 195.5 666.1 5.6 6.2 13.1 11.3 16.9 39.3 26.5 20.1 14.1 8.3 18.0 14.1 24.5 31.1 MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 13.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" 1.0 2.1 0.8 1.9 1.1 2.8 1.8 1.7 1.4 1.3 1.1 1.6 2.0 1.7 2.7 1.2 1.4 1.3 1.4 0.8 1.0 1.8 2.5 1.2 2.5 1.1 0.9 2.3 2.6 1.0 1.7 1.0 1.0 1.7 2.0 2.5 1.6 1.4 1.2 4.2 1.8 1.4 0.9 1.9 2.0 5.3 1.0 1.9 1.9 0.7 2.5 1.4 0.9 1.2 1.2 3.9 1.9 3.1 1.2 1.0 2.1 2.4 1.2 1.5 3.7 3.5 6.0 2.2 2.4 0.5 2.4 3.9 2.6 2.8 1.9 1.5 2.5 1.0 13.6 1.9 1.1 2.4 2.5 1.9 1.3 2.5 2.4 1.8 1.4 3.8 0.9 3.9 1.1 1.7 3.2 5.1 0.9 1.5 0.6 3.4 2.0 5.1 2.0 1.7 0.9 1.4 1.7 1.0 1.7 1.3 1.8 1.1 1.5 1.8 3.0 1.7 1.9 8.6 4.1 4.4 3.4 2.9 2.6 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.7 1.4 0.8 1.0 1.1 0.9 1.0 0.9 1.0 1.2 0.5 0.0 1.5 0.0 0.5 0.3 0.3 0.7 0.6 0.0 0.6 0.5 1.4 1.5 1.4 0.0 0.0 0.2 0.8 0.6 0.0 0.8 0.0 0.7 0.3 0.5 1.8 3.2 0.0 1.2 0.4 0.6 0.0 0.6 0.0 2.2 0.4 2.0 0.4 0.0 0.0 0.0 0.0 1.0 0.3 0.6 1.2 0.8 1.8 0.0 1.0 0.0 1.0 0.0 0.0 1.0 0.2 0.4 0.9 0.3 0.3 0.3 2.4 0.0 0.0 0.6 0.4 0.6 0.2 0.4 0.9 0.3 0.7 0.8 0.5 0.1 MTFR1L FAM54B ENSG00000117640 "Mitochondrial fission regulator 1 like" Q9H019 1 25818640-25832942 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 161.1;Early spermatids: 216.1;Late spermatids: 590.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027124, HPA027130" Approved Approved "Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" Mitochondria "Cell Junctions" "HPA027124: AB_10600211, HPA027130: AB_10611251" "unprognostic (9.90e-2)" "unprognostic (6.86e-3)" "unprognostic (9.29e-2)" "prognostic favorable (6.81e-4)" "unprognostic (1.16e-1)" "unprognostic (1.58e-2)" "unprognostic (1.43e-1)" "unprognostic (4.52e-3)" "unprognostic (2.12e-1)" "unprognostic (2.24e-1)" "unprognostic (9.89e-3)" "unprognostic (5.33e-2)" "prognostic favorable (5.89e-12)" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (2.69e-1)" "unprognostic (1.33e-1)" 39.0 138.0 79.6 22.2 82.8 17.8 37.4 80.0 88.4 51.0 84.6 74.1 46.8 51.0 57.8 39.4 44.9 32.7 169.1 81.7 81.3 71.7 91.3 32.4 25.8 80.2 83.8 68.4 46.0 106.0 51.6 40.7 79.6 55.8 37.3 62.1 43.3 70.1 221.8 35.6 46.9 50.0 78.6 44.2 56.6 82.5 83.2 24.7 48.1 239.7 26.3 58.3 40.5 78.5 19.5 26.7 53.2 53.6 67.6 63.8 22.2 44.7 63.7 45.2 49.9 8.7 39.7 6.6 38.9 80.1 40.0 17.4 44.1 38.6 44.8 43.9 39.8 55.6 44.3 35.9 64.6 45.5 52.9 65.3 36.4 48.3 36.1 67.0 37.9 27.0 34.7 29.2 66.1 21.6 26.3 33.6 29.4 26.0 39.4 26.0 47.4 19.8 47.1 18.3 53.6 48.5 33.6 32.4 67.8 35.8 26.7 43.1 38.6 36.7 28.9 86.6 28.5 30.5 19.3 23.2 63.6 62.5 41.2 71.7 50.5 111.7 25.7 50.8 15.6 28.1 24.1 22.9 55.0 28.8 25.4 23.1 13.6 27.6 58.3 22.7 27.3 51.1 79.6 82.8 80.0 88.4 81.7 81.3 80.2 83.8 79.6 78.6 83.2 78.5 18.7 16.0 24.5 24.2 14.1 13.5 20.8 38.6 25.0 0.0 21.6 23.6 161.1 25.8 21.7 22.0 0.0 55.9 14.8 15.7 103.7 32.4 216.1 11.3 16.7 17.1 15.6 12.4 18.2 33.5 36.7 28.4 21.4 10.6 36.1 21.9 21.4 35.5 34.9 0.0 24.1 14.9 34.6 15.1 17.3 590.4 34.2 25.6 44.4 6.5 43.5 0.0 12.3 12.5 15.2 27.7 15.0 39.1 15.4 16.2 39.3 70.6 10.5 0.0 26.3 23.3 31.3 144.7 49.9 15.4 12.9 59.4 13.1 29.8 18.0 16.5 MTHFR ENSG00000177000 "Methylenetetrahydrofolate reductase" P42898 1 11785723-11806455 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Allosteric enzyme, Oxidoreductase" "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 44.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063389, HPA076180, HPA077255" Enhanced Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "HPA063389: AB_2685001, HPA076180: , HPA077255: " "unprognostic (3.25e-2)" "unprognostic (8.19e-2)" "unprognostic (4.48e-2)" "unprognostic (2.11e-2)" "unprognostic (1.34e-1)" "prognostic favorable (3.97e-5)" "prognostic unfavorable (1.19e-4)" "unprognostic (1.75e-2)" "unprognostic (2.85e-1)" "unprognostic (8.69e-2)" "prognostic favorable (4.81e-5)" "unprognostic (3.10e-1)" "prognostic favorable (2.12e-4)" "unprognostic (2.35e-3)" "unprognostic (2.94e-1)" "unprognostic (4.14e-2)" "unprognostic (1.80e-2)" 12.3 11.3 7.1 10.8 10.3 28.9 10.2 12.8 8.8 9.0 5.0 11.1 10.8 8.9 53.5 10.3 12.3 10.1 23.9 10.4 6.2 12.8 13.1 16.8 12.3 9.9 7.0 19.7 11.4 6.6 17.7 7.1 9.4 10.2 8.7 12.6 6.8 6.7 17.9 13.4 14.7 10.8 5.1 18.3 14.6 10.9 8.0 7.9 16.3 16.8 12.2 10.3 7.9 8.9 2.2 9.4 10.9 12.3 10.2 15.1 2.0 5.2 14.6 6.0 5.1 8.1 13.2 18.0 3.6 7.5 16.3 4.1 8.1 7.7 2.4 9.3 6.8 13.4 13.3 3.2 13.7 7.4 16.4 13.6 6.1 8.0 6.4 10.0 10.7 17.2 44.1 11.0 6.7 3.3 8.2 3.5 3.6 9.5 3.0 8.9 6.0 20.3 8.8 11.7 10.5 17.6 8.1 7.8 10.9 6.2 12.9 11.7 8.5 6.0 4.9 7.2 1.6 6.4 9.4 32.8 7.6 16.8 5.6 0.7 2.3 1.1 2.7 4.3 0.9 1.6 0.8 1.4 1.7 2.3 1.2 1.4 2.5 2.0 6.1 0.9 0.6 1.6 7.1 10.3 12.8 8.8 10.4 6.2 9.9 7.0 9.4 5.1 8.0 8.9 15.9 25.6 48.0 8.1 18.3 8.4 6.8 11.9 15.9 0.0 17.9 10.8 37.0 11.5 13.0 27.6 0.0 5.1 6.0 44.2 1.9 8.9 18.2 32.0 25.8 16.9 12.1 29.5 15.8 25.3 3.3 21.0 52.5 55.5 8.2 10.7 37.5 23.4 22.2 0.0 15.2 18.0 6.1 39.3 39.9 42.4 18.3 32.1 12.4 16.9 26.5 0.0 20.6 9.0 13.3 21.9 20.6 9.1 10.3 10.2 36.0 17.2 12.3 0.0 19.7 22.8 23.3 6.8 5.2 15.0 9.2 2.9 10.6 21.3 18.6 9.6 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568621-150673143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.2;Oligodendrocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favorable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 6.8 11.1 7.4 9.7 8.3 11.3 7.6 8.0 8.4 5.7 6.1 19.8 11.7 6.5 8.4 7.5 9.6 7.1 7.3 6.9 8.5 12.9 18.4 11.2 12.4 7.8 8.6 11.7 4.9 16.0 3.8 6.3 8.0 8.0 19.2 5.4 6.3 10.7 11.8 8.2 12.1 6.9 7.7 11.9 7.8 11.5 8.8 8.4 11.2 10.1 9.7 7.1 4.7 8.8 14.3 6.1 8.5 3.1 7.5 7.3 5.4 6.1 8.5 7.0 7.9 4.7 7.3 22.2 11.4 8.3 21.9 9.9 6.1 11.5 8.6 6.4 5.2 5.6 5.4 15.0 5.8 25.2 19.1 4.5 14.3 5.7 11.9 6.9 9.4 9.3 3.9 19.8 8.8 4.5 6.9 25.2 4.3 13.4 7.4 8.0 4.9 4.5 11.7 6.9 2.2 2.4 5.5 11.3 8.5 11.9 4.1 35.2 8.2 5.0 3.1 12.4 7.1 4.2 10.0 20.3 6.0 14.8 8.0 34.8 9.5 27.9 2.0 10.8 6.8 8.0 9.6 7.3 12.0 10.6 9.0 5.4 11.6 14.6 9.8 7.4 12.2 7.1 7.4 8.3 8.0 8.4 6.9 8.5 7.8 8.6 8.0 7.7 8.8 8.8 9.9 9.6 20.0 52.2 13.9 15.2 8.3 5.8 2.2 0.0 5.8 3.9 15.0 4.3 6.0 3.7 0.0 2.1 8.4 33.0 1.9 3.4 35.6 7.7 5.0 11.5 9.6 7.4 44.0 4.3 2.8 6.6 8.2 4.8 8.8 3.3 16.4 13.2 8.0 0.0 41.5 17.7 2.0 16.3 10.4 18.8 6.2 13.0 5.4 24.4 12.0 0.0 0.0 27.6 47.7 4.7 9.5 12.8 8.0 6.8 11.2 14.7 13.4 0.0 0.0 5.2 6.9 5.1 4.1 4.9 19.0 7.3 12.8 4.8 13.8 9.7 MTPN "GCDP, MYOTROPHIN, V-1" ENSG00000105887 Myotrophin P58546 7 135926760-135977359 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019735 Approved Approved "Plasma membrane,Cytosol" NA NA 14000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA019735: AB_1858710" "unprognostic (5.97e-2)" "unprognostic (2.53e-2)" "unprognostic (8.52e-2)" "unprognostic (3.62e-3)" "unprognostic (2.20e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.06e-3)" "unprognostic (3.30e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (4.50e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (2.43e-1)" "unprognostic (9.00e-3)" "unprognostic (4.86e-3)" 68.9 49.5 66.7 65.1 75.5 151.1 50.7 41.6 79.4 67.1 45.6 50.5 40.2 65.1 50.9 125.5 62.2 50.5 77.1 79.5 65.0 58.5 49.7 57.8 89.4 77.7 60.0 49.2 23.8 75.9 34.0 61.7 54.0 52.9 55.4 39.9 36.8 51.3 47.6 46.8 46.6 66.1 56.3 79.7 41.2 56.6 65.2 72.5 88.2 48.0 107.8 67.2 58.5 53.3 126.0 90.6 111.5 170.4 160.3 187.2 55.8 189.5 208.0 129.3 137.7 104.5 139.4 229.7 132.7 255.6 188.6 78.9 107.1 161.1 246.1 153.1 84.2 152.9 94.6 77.2 127.3 211.5 213.5 136.5 158.5 152.9 147.7 180.1 205.5 163.6 182.3 138.1 253.2 94.3 208.4 163.0 155.9 121.9 118.9 120.0 83.8 187.7 144.5 103.1 140.6 248.3 157.1 105.8 158.4 102.8 75.4 130.7 215.2 193.5 85.0 192.3 189.7 103.8 160.2 325.9 307.5 185.0 420.2 117.4 75.4 85.2 54.7 105.7 46.0 107.9 33.5 41.7 89.3 125.0 21.5 31.7 180.3 46.0 169.4 82.8 32.6 70.5 66.7 75.5 41.6 79.4 79.5 65.0 77.7 60.0 54.0 56.3 65.2 53.3 110.6 48.1 40.6 0.0 149.8 119.2 58.9 86.8 72.8 0.0 68.6 72.8 82.0 70.1 61.9 69.9 0.0 63.4 131.6 67.1 90.1 69.6 77.8 83.8 153.3 108.5 33.0 91.9 0.0 51.3 73.1 92.4 45.9 131.9 98.6 64.8 87.4 59.2 100.5 0.0 0.0 46.9 46.8 247.5 232.7 28.6 86.3 214.0 101.4 0.0 234.2 0.0 125.7 0.0 0.0 99.9 67.0 123.8 59.2 96.2 52.6 88.3 50.0 0.0 92.1 99.8 79.8 65.8 123.8 143.3 149.0 68.8 86.1 106.5 52.4 106.9 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MUC20 "FLJ14408, KIAA1359" ENSG00000176945 "Mucin 20, cell surface associated" Q8N307 3 195720884-195741123 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 58.5;kidney: 69.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 53.2;Ductal cells: 55.5;Ionocytes: 152.5;Respiratory ciliated cells: 66.5;Urothelial cells: 84.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "SK-BR-3: 28.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042249 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042249: " "unprognostic (1.85e-1)" "unprognostic (4.64e-2)" "unprognostic (1.05e-2)" "unprognostic (1.83e-3)" "unprognostic (2.12e-1)" "unprognostic (1.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.41e-1)" "unprognostic (3.99e-4)" "unprognostic (7.66e-2)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.57e-4)" "unprognostic (2.05e-1)" "unprognostic (2.56e-1)" "unprognostic (3.98e-3)" "unprognostic (1.17e-1)" 6.7 5.1 4.3 1.3 5.0 0.9 7.9 7.0 6.7 23.0 3.0 30.0 3.0 5.0 4.5 58.5 20.0 6.4 6.3 3.6 3.4 69.7 21.1 7.9 0.8 4.1 2.7 11.8 16.1 2.0 16.5 0.5 4.0 20.9 7.2 8.1 40.3 1.1 7.0 8.0 14.7 0.8 1.4 6.1 9.8 8.5 4.2 0.8 16.2 1.0 1.4 21.0 26.0 5.0 0.9 0.0 0.2 0.7 0.4 0.0 0.7 0.0 0.2 0.0 0.1 0.0 3.7 0.1 0.7 0.0 0.2 1.5 0.1 0.0 0.1 1.3 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.4 0.1 0.7 3.9 0.1 1.0 0.1 1.1 0.1 3.6 1.3 0.4 0.0 28.1 0.2 0.5 0.2 0.0 0.0 0.2 0.8 1.0 0.1 1.3 1.7 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.3 5.0 7.0 6.7 3.6 3.4 4.1 2.7 4.0 1.4 4.2 5.0 0.9 35.3 16.7 16.6 0.5 1.8 10.0 6.4 0.6 19.9 3.2 1.5 0.7 14.3 43.7 22.0 35.5 0.1 0.2 53.2 1.9 55.5 0.1 3.5 1.3 1.7 13.8 5.3 7.5 9.9 0.1 1.8 13.3 6.2 1.3 5.3 3.3 7.3 0.5 11.8 7.7 7.3 152.5 1.0 0.8 0.4 5.3 1.1 3.6 1.0 0.0 4.7 0.0 5.0 3.0 12.2 16.9 6.4 1.7 14.2 16.9 3.3 66.5 20.5 0.0 8.8 3.3 1.3 1.3 4.3 1.8 0.0 1.7 1.0 15.2 84.4 MUC3A MUC3 ENSG00000169894 "Mucin 3A, cell surface associated" Q02505 7 100949534-100968347 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "gallbladder: 13.8;intestine: 41.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 220.6;Intestinal goblet cells: 114.2;Paneth cells: 157.1;Proximal enterocytes: 360.1;Undifferentiated cells: 129.5" "Group enriched" "Detected in many" 5 "colorectal cancer: 16.4;pancreatic cancer: 14.0;stomach cancer: 29.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 7.3;CAPAN-2: 2.4;MCF7: 1.6;OE19: 3.7" "Region enriched" "Detected in many" 7 "cerebellum: 16.5" "HPA010871, HPA047868" Uncertain Uncertain "Cell Junctions" "Intracellular and membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Cell Junctions" "HPA010871: AB_1854201, HPA047868: " "unprognostic (1.12e-2)" "unprognostic (3.78e-2)" "unprognostic (1.75e-1)" "unprognostic (4.22e-3)" "unprognostic (2.91e-1)" "unprognostic (5.16e-2)" "unprognostic (2.06e-1)" "unprognostic (5.29e-3)" "unprognostic (2.87e-1)" "unprognostic (1.33e-1)" "unprognostic (7.01e-2)" "unprognostic (2.99e-1)" "unprognostic (6.50e-3)" "unprognostic (8.73e-2)" "unprognostic (1.01e-1)" "unprognostic (2.39e-1)" "unprognostic (4.51e-2)" 1.0 0.0 0.0 1.3 0.0 0.0 0.7 0.0 0.6 0.0 0.0 9.4 41.7 0.0 0.0 0.0 0.0 13.8 3.2 0.0 0.8 0.2 8.7 0.2 0.3 0.0 0.3 0.0 0.5 0.8 0.0 0.0 0.0 3.1 11.9 0.0 0.1 0.0 5.0 0.1 33.5 0.8 0.0 0.1 2.7 0.1 0.1 9.9 0.8 0.5 0.3 0.4 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 7.3 2.4 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.6 0.0 0.0 1.0 3.7 0.0 0.0 0.0 0.2 0.3 0.0 0.5 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.3 0.0 0.0 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 27.2 0.0 0.0 0.0 1.0 0.4 2.1 28.6 0.0 1.8 0.0 0.7 0.0 220.6 0.0 18.8 0.8 0.0 0.1 0.8 10.3 0.0 0.1 28.8 1.1 0.4 15.8 0.0 0.0 0.0 0.4 5.3 0.3 0.0 0.0 114.2 0.0 0.8 0.0 0.4 0.3 0.2 0.0 0.0 1.0 0.0 0.0 0.0 0.1 28.9 157.1 0.0 0.0 65.7 360.1 0.3 0.0 0.0 0.0 0.4 6.4 0.8 6.8 0.0 0.1 0.3 0.4 0.0 129.5 21.3 MVD MPD ENSG00000167508 "Mevalonate diphosphate decarboxylase" P53602 16 88651935-88663161 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Cholesterol biosynthesis, Cholesterol metabolism, Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Lyase "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 147.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041404, HPA048250" Uncertain Approved "Cell Junctions,Cytosol" NA NA 170000 "Cluster 15: NK-cells - Transcription" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 15: Hepatocytes - Hemostasis" Cytosol "Cell Junctions" "HPA041404: AB_2677457, HPA048250: AB_2680329" "unprognostic (1.67e-1)" "unprognostic (3.05e-1)" "unprognostic (2.42e-1)" "prognostic favorable (2.17e-4)" "unprognostic (1.89e-1)" "unprognostic (9.56e-2)" "unprognostic (9.26e-3)" "unprognostic (8.33e-2)" "unprognostic (6.68e-2)" "unprognostic (5.47e-2)" "unprognostic (2.51e-1)" "unprognostic (6.22e-2)" "unprognostic (1.19e-3)" "unprognostic (4.12e-2)" "unprognostic (1.69e-1)" "unprognostic (2.11e-1)" "unprognostic (5.00e-2)" 20.3 51.1 24.2 15.7 27.5 7.0 16.4 26.2 37.5 30.5 19.3 32.3 35.1 20.3 2.2 77.8 13.5 4.9 22.8 24.7 27.8 28.8 78.8 31.0 12.3 32.4 27.8 19.6 25.3 8.3 18.9 6.3 39.3 23.5 4.2 3.4 25.1 6.5 27.2 52.3 26.6 5.7 24.0 24.6 31.5 42.3 24.7 7.0 21.1 8.3 6.8 17.6 36.9 25.6 50.6 34.2 52.4 33.1 18.1 38.7 29.5 25.1 26.0 17.7 14.6 86.1 119.7 24.4 39.8 15.7 63.7 72.8 25.0 133.1 4.9 15.7 38.3 17.8 18.2 127.0 35.9 11.6 11.8 30.9 24.6 46.6 13.5 8.7 18.0 58.0 51.7 13.1 10.2 115.9 39.3 56.6 61.5 17.7 31.3 40.2 15.0 62.3 49.8 33.0 52.2 17.9 62.0 13.3 18.5 11.4 67.8 51.3 39.0 14.7 29.8 27.2 14.2 34.9 17.6 83.2 17.9 55.7 25.7 5.6 12.6 2.4 26.8 13.7 20.4 16.1 18.0 17.9 15.0 22.6 13.2 16.6 1.8 28.3 15.4 28.0 20.4 15.4 24.2 27.5 26.2 37.5 24.7 27.8 32.4 27.8 39.3 24.0 24.7 25.6 17.2 25.6 48.2 22.2 21.5 15.2 12.9 106.3 4.0 27.2 26.5 14.1 16.7 21.5 56.9 20.2 6.2 20.2 79.6 117.5 25.4 30.8 61.6 17.7 10.0 15.8 32.9 26.5 23.4 62.3 29.2 15.5 41.8 26.5 16.5 27.4 20.7 147.2 38.6 23.5 17.0 75.3 32.6 25.5 21.6 96.2 8.1 20.3 21.4 6.5 32.2 16.5 55.6 11.1 14.5 30.0 79.4 9.1 46.3 20.1 47.1 22.6 21.5 18.1 6.6 7.0 20.7 50.8 13.0 13.8 21.6 48.8 36.3 35.5 65.2 20.6 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYH9 "DFNA17, EPSTS, FTNS, MHA, NMHC-II-A, NMMHCA" ENSG00000100345 "Myosin heavy chain 9" P35579 22 36281280-36387967 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell shape" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Alport syndrome, Cancer-related genes, Cataract, Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "TIME: 1343.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001644, CAB015386, HPA064783" Enhanced Supported "Nuclear bodies,Plasma membrane,Actin filaments,Cytosol" No No 410000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 82: Adipose tissue - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Actin filaments" "Nuclear bodies, Cytosol" "CAB015386: AB_784698, HPA001644: AB_1079439, HPA064783: AB_2732721" "unprognostic (1.38e-1)" "unprognostic (9.12e-2)" "unprognostic (4.21e-2)" "unprognostic (6.34e-2)" "unprognostic (1.49e-1)" "unprognostic (3.90e-2)" "unprognostic (9.56e-2)" "unprognostic (8.28e-2)" "unprognostic (5.50e-2)" "unprognostic (6.38e-2)" "unprognostic (1.93e-2)" "unprognostic (1.61e-1)" "unprognostic (7.98e-2)" "unprognostic (9.48e-2)" "unprognostic (1.64e-1)" "unprognostic (1.62e-1)" "unprognostic (2.59e-2)" 295.9 95.5 42.3 181.1 42.1 245.9 231.5 40.6 54.7 181.2 65.5 192.6 107.0 356.4 39.3 153.8 182.2 134.5 161.1 50.8 39.4 140.7 101.6 286.2 161.7 52.7 51.7 121.1 160.3 55.0 52.6 166.5 48.1 131.8 89.8 9.7 177.2 98.4 84.0 160.6 163.5 174.1 48.8 232.5 135.8 38.2 52.1 125.1 141.2 46.3 104.1 168.8 166.8 48.2 612.2 277.0 86.2 74.2 156.8 195.1 437.3 398.4 507.5 554.6 413.2 302.1 170.3 156.9 230.1 666.1 265.0 412.7 125.2 779.4 559.6 356.1 120.9 302.6 294.3 259.9 481.1 346.9 463.8 233.0 234.7 751.9 626.4 540.3 461.8 113.2 67.3 205.8 448.9 161.9 124.4 204.0 51.7 171.1 169.2 233.3 267.3 146.7 314.5 581.5 129.6 53.0 559.7 217.0 251.6 218.5 162.4 177.1 1343.7 1222.6 370.3 237.5 731.5 135.2 114.7 129.0 463.2 172.3 363.1 72.6 25.2 64.7 32.4 19.8 28.4 13.4 23.5 26.4 17.2 11.9 18.3 20.4 41.2 9.0 26.5 8.0 26.3 54.5 42.3 42.1 40.6 54.7 50.8 39.4 52.7 51.7 48.1 48.8 52.1 48.2 303.9 118.6 87.1 12.7 108.4 144.0 182.4 123.1 72.8 2.6 90.5 89.4 62.6 80.1 89.7 92.0 2.1 87.0 151.7 359.8 7.9 309.4 35.8 89.7 121.6 258.7 73.8 51.9 42.5 245.8 193.1 82.9 123.8 194.7 93.1 117.1 132.8 102.8 100.4 82.4 6.7 131.0 59.0 119.6 124.2 37.4 68.0 168.8 85.4 61.8 196.6 11.9 137.0 7.5 33.3 344.6 186.8 211.4 125.9 184.4 159.8 27.5 51.5 5.3 203.8 39.9 275.2 6.9 10.4 133.6 135.1 46.4 213.2 141.3 139.5 134.3 MYL4 "ALC1, AMLC, GT1, PRO1957" ENSG00000198336 "Myosin light chain 4" P12829 17 47200446-47223679 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "heart muscle: 6347.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2426.3" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 11.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.8" "Cell line enriched" "Detected in some" 4 "HEL: 552.8" "Group enriched" "Detected in all" 6 "amygdala: 25.8;cerebral cortex: 88.4;hippocampal formation: 25.2;white matter: 50.9" "Not detected" "Not detected" "HPA046859, HPA051884, HPA063034" Enhanced Approved "Plasma membrane" NA NA 3100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA046859: AB_2679842, HPA051884: AB_2681651, HPA063034: AB_2684927" "unprognostic (2.43e-2)" "unprognostic (9.57e-2)" "unprognostic (2.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.33e-1)" "unprognostic (4.12e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.52e-2)" "unprognostic (2.10e-2)" "unprognostic (7.37e-2)" "unprognostic (1.00e-6)" "unprognostic (1.92e-4)" "unprognostic (2.54e-1)" "unprognostic (6.51e-3)" "unprognostic (1.50e-1)" 2.1 0.5 0.2 0.4 0.3 134.6 2.7 0.2 0.4 0.4 0.4 0.8 0.8 0.8 0.0 0.6 0.5 1.0 6347.0 0.3 0.4 1.3 1.4 9.4 0.9 0.3 0.3 0.8 8.6 0.3 0.5 9.1 0.4 1.1 0.3 42.2 3.0 0.2 3.5 1.2 1.3 0.8 0.2 3.1 3.4 15.5 0.3 2.4 11.0 6.4 0.4 0.9 0.8 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.9 0.3 0.0 0.2 0.0 0.9 0.1 1.6 0.9 0.0 0.4 0.0 0.1 0.0 0.0 3.0 0.2 552.8 0.1 0.0 0.0 0.0 0.3 21.2 0.0 0.3 0.1 0.0 1.0 1.4 133.3 0.3 0.2 0.0 10.0 0.1 0.3 0.0 0.4 0.3 12.9 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 24.3 0.0 0.2 4.5 0.0 0.3 0.1 0.0 0.3 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.3 0.2 0.4 0.3 0.4 0.3 0.3 0.4 0.2 0.3 0.4 3.2 3.2 0.0 0.0 0.7 0.8 0.0 0.0 0.0 5.5 0.0 0.0 2426.3 0.0 0.0 0.0 64.6 0.5 2.7 0.1 0.0 0.1 23.3 0.1 0.0 23.2 0.0 412.8 0.1 0.0 3.9 150.7 1.5 0.1 0.0 0.3 1.8 0.5 1.9 1.7 0.0 0.8 0.0 0.6 0.6 54.6 3.4 34.0 12.4 0.0 1.5 7.9 4.1 0.0 0.1 0.1 0.0 1.5 0.8 0.0 10.9 0.2 0.0 24.4 0.0 0.6 36.5 9.9 0.5 0.0 0.9 1.4 0.3 0.2 1.0 0.0 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO10 KIAA0799 ENSG00000145555 "Myosin X" Q9HD67 5 16661907-16936288 "Plasma proteins, Predicted intracellular proteins" Transport "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 189.5;Muller glia cells: 233.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "non-classical monocyte: 2.5" "Lineage enriched" "Detected in single" 5 "monocytes: 2.5" "Cell line enhanced" "Detected in many" "HeLa: 182.1;SK-MEL-30: 205.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015224, HPA024223" Enhanced Supported "Nucleoli rim,Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoli rim" "CAB015224: , HPA024223: AB_1854248" "unprognostic (1.13e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (7.63e-2)" "unprognostic (1.04e-1)" "unprognostic (4.43e-2)" "unprognostic (2.96e-2)" "unprognostic (4.40e-2)" "unprognostic (8.34e-2)" "unprognostic (2.51e-2)" "unprognostic (3.16e-2)" "unprognostic (8.42e-2)" "unprognostic (1.85e-1)" "prognostic favorable (2.75e-4)" "unprognostic (8.93e-2)" "unprognostic (9.86e-2)" "unprognostic (4.56e-2)" "unprognostic (1.84e-1)" 13.8 3.0 47.4 6.2 46.3 3.2 7.9 24.6 41.1 6.7 55.1 19.3 22.8 6.2 3.5 9.3 4.3 8.4 4.5 39.8 24.8 14.7 7.7 19.0 1.3 32.6 30.9 15.8 32.2 10.7 9.5 31.5 27.6 5.8 19.1 15.1 11.0 5.0 8.2 15.6 19.5 4.9 27.3 13.9 32.0 15.6 46.4 4.9 37.5 4.4 2.0 11.1 7.8 45.7 68.2 108.3 31.3 14.9 24.7 17.0 35.1 117.2 89.2 35.5 27.4 63.1 10.2 1.5 78.9 52.9 42.3 33.4 139.1 73.7 57.1 0.2 16.7 0.1 182.1 13.7 81.5 0.4 1.5 30.9 26.8 78.5 92.1 57.4 110.5 0.2 0.2 4.8 28.7 10.5 0.2 0.4 80.5 56.6 37.2 26.1 10.3 66.9 22.0 49.6 5.2 2.8 27.0 11.4 205.0 53.2 8.1 9.1 137.8 77.6 23.6 0.7 61.1 0.7 0.5 0.5 38.3 11.2 76.2 0.5 0.2 0.2 0.1 0.5 0.1 0.1 0.1 0.1 0.2 0.3 0.2 0.2 0.3 0.1 2.5 0.1 0.1 0.1 47.4 46.3 24.6 41.1 39.8 24.8 32.6 30.9 27.6 27.3 46.4 45.7 53.5 35.3 34.6 158.7 1.4 40.9 31.0 23.0 29.6 11.0 18.6 11.6 3.8 55.8 26.3 31.3 18.8 20.4 0.3 46.4 17.6 110.8 30.2 118.5 20.8 61.3 74.0 0.0 3.9 40.6 63.4 13.7 68.3 116.0 27.8 189.5 77.1 1.7 5.6 82.4 5.4 53.2 20.3 7.1 4.8 9.5 12.8 5.7 67.6 87.1 3.8 233.8 0.0 103.5 23.5 114.7 50.3 19.2 0.4 42.6 28.3 4.2 18.8 9.2 65.7 8.2 31.5 3.8 12.2 30.7 31.8 147.8 2.4 4.1 66.9 38.6 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYO1E "HuncM-IC, MGC104638, MYO1C" ENSG00000157483 "Myosin IE" Q12965 15 59132434-59372871 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 319.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 23.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 224.1;HaCaT: 208.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003003, HPA023886" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 13000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" Cytosol "HPA003003: , HPA023886: AB_1854253" "unprognostic (7.90e-2)" "unprognostic (1.35e-1)" "unprognostic (1.52e-1)" "prognostic favorable (4.19e-4)" "unprognostic (1.49e-1)" "unprognostic (3.59e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (1.89e-1)" "unprognostic (5.38e-3)" "prognostic unfavorable (7.99e-4)" "unprognostic (2.41e-1)" "unprognostic (7.92e-2)" "unprognostic (7.31e-2)" "unprognostic (9.71e-2)" "unprognostic (1.15e-1)" "unprognostic (5.62e-2)" 30.6 7.1 19.4 32.9 34.9 1.8 19.5 32.2 30.7 27.7 43.6 54.3 25.3 31.0 29.6 37.6 17.4 38.7 13.3 19.6 24.9 47.7 52.2 19.9 36.9 38.6 35.0 10.3 12.0 22.4 9.3 34.7 39.4 22.9 34.4 9.9 18.7 21.6 11.9 45.6 44.2 22.2 28.4 17.1 32.5 8.3 33.1 7.6 15.2 10.9 41.2 38.1 28.1 57.1 133.3 224.1 12.1 8.2 92.4 74.8 62.2 52.9 25.7 28.8 33.6 55.7 50.5 52.7 37.0 41.3 117.5 208.6 18.9 81.5 38.2 24.1 10.5 0.5 178.4 50.3 85.5 0.3 7.2 103.4 48.8 37.0 107.4 90.7 47.8 0.9 0.3 0.8 49.2 12.4 0.6 1.2 29.3 21.5 49.8 0.2 53.8 32.4 156.9 61.8 6.5 21.9 117.1 24.2 45.8 36.5 16.3 5.8 58.4 57.5 16.6 177.1 52.0 0.3 3.3 1.3 105.4 0.6 53.2 0.0 4.5 0.0 0.2 4.6 0.0 9.2 0.0 0.0 15.4 8.6 0.0 0.0 0.6 3.6 1.6 23.7 0.5 2.5 19.4 34.9 32.2 30.7 19.6 24.9 38.6 35.0 39.4 28.4 33.1 57.1 31.0 6.4 7.7 27.1 19.6 24.9 40.0 24.7 24.5 0.2 9.3 10.2 3.9 17.2 15.4 25.8 0.0 4.3 19.9 73.6 3.9 39.8 4.2 49.4 30.2 30.4 19.7 2.5 9.3 18.1 23.8 14.9 86.6 47.3 4.5 6.7 5.0 13.0 33.5 0.0 8.7 31.2 8.2 5.0 50.1 8.5 9.3 17.6 19.6 56.2 9.0 11.3 3.1 6.6 319.1 64.0 60.0 12.0 9.2 28.3 37.4 3.1 40.9 0.9 13.1 33.7 25.0 1.3 5.1 30.1 24.0 12.9 4.7 6.7 29.3 56.9 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYO3A DFNB30 ENSG00000095777 "Myosin IIIA" Q8NEV4 10 25934229-26212532 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Hearing, Sensory transduction, Vision" "Actin-binding, Kinase, Motor protein, Myosin, Serine/threonine-protein kinase, Transferase" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 15.5;testis: 5.2" "Cell type enhanced" "Detected in some" "Early spermatids: 156.6;Late spermatids: 58.2;Muller glia cells: 74.8;Spermatocytes: 31.7" "Cancer enhanced" "Detected in many" "cervical cancer: 1.7" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 1.3;CAPAN-2: 1.2;HEK 293: 1.5;SCLC-21H: 1.4;U-2 OS: 2.4;U-698: 6.3" "Not detected" "Not detected" "HPA051893, HPA075413" Enhanced Supported "Plasma membrane,Actin filaments,Cytoplasmic bodies" No No "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Actin filaments, Cytoplasmic bodies" "Plasma membrane" "HPA051893: , HPA075413: " "unprognostic (5.00e-3)" "unprognostic (3.36e-2)" "unprognostic (1.53e-1)" "unprognostic (3.20e-3)" "unprognostic (2.96e-1)" "unprognostic (4.37e-2)" "unprognostic (5.29e-2)" "unprognostic (2.74e-1)" "unprognostic (4.31e-2)" "unprognostic (1.03e-1)" "unprognostic (5.66e-3)" "unprognostic (7.96e-3)" "unprognostic (6.34e-2)" "unprognostic (1.46e-2)" "unprognostic (6.62e-2)" "unprognostic (9.69e-2)" 0.1 0.1 0.4 0.0 1.8 0.1 0.1 0.0 0.8 0.1 0.2 0.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.1 0.6 0.3 0.0 0.1 0.0 0.6 0.5 0.0 0.7 0.0 0.5 0.0 0.5 0.1 0.3 15.5 0.0 0.1 0.0 0.7 0.1 0.0 0.2 0.0 0.2 5.2 0.3 0.2 0.2 0.1 0.2 0.0 0.3 0.3 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.9 0.8 0.0 0.0 0.7 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.8 0.1 0.6 0.6 0.5 0.5 0.2 0.3 0.3 0.2 0.0 0.5 2.0 0.1 1.8 0.3 0.0 0.0 0.9 0.6 0.3 0.6 0.0 2.5 0.0 0.0 0.0 0.0 0.2 1.9 0.8 156.6 0.6 0.1 0.3 1.8 0.0 2.2 0.0 0.4 0.6 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 5.9 0.4 0.0 0.0 0.0 58.2 1.2 0.1 0.0 1.9 0.0 74.8 0.0 1.0 0.4 0.2 0.0 1.2 0.0 0.3 0.0 1.0 0.0 3.9 0.0 0.0 2.4 31.7 14.2 2.4 1.0 0.0 0.0 0.0 0.4 0.3 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 MYO9A "FLJ11061, FLJ13244, MGC71859" ENSG00000066933 "Myosin IXA" B2RTY4 15 71822291-72118577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, GTPase activation, Motor protein, Myosin" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 61.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 225.5;Inhibitory neurons: 192.9;Rod photoreceptor cells: 462.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039812, HPA040071" Approved Approved "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA039812: AB_10961421, HPA040071: AB_10961117" "unprognostic (7.53e-2)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.42e-3)" "unprognostic (1.63e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (3.56e-2)" "unprognostic (1.26e-1)" "unprognostic (5.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.14e-4)" "unprognostic (3.44e-1)" "unprognostic (4.41e-1)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" 6.5 3.9 11.3 4.8 14.9 4.8 10.7 14.3 13.3 8.7 2.5 7.1 2.1 9.9 7.4 7.7 7.2 5.2 6.7 12.8 9.2 13.7 3.7 8.8 6.4 8.7 8.0 12.1 3.3 7.4 4.7 7.6 9.2 8.0 6.3 61.7 4.5 7.5 8.1 8.7 4.6 10.2 6.7 7.3 5.2 28.7 9.5 6.7 13.2 14.9 6.4 6.5 6.1 13.5 9.7 14.6 9.6 6.8 14.2 16.5 5.7 9.1 9.8 9.0 9.1 7.1 6.6 43.3 5.4 17.9 11.8 9.0 19.2 10.3 11.9 9.5 11.1 11.1 8.9 3.2 9.0 11.2 8.5 9.5 10.2 10.6 15.2 7.6 11.5 7.7 7.2 10.3 12.2 6.0 6.4 4.5 5.2 3.5 5.9 4.6 18.2 4.3 10.9 14.3 5.4 5.9 12.0 10.0 9.5 11.6 8.0 5.3 15.5 18.0 8.7 29.7 10.4 6.5 17.3 11.3 10.8 9.2 8.1 1.7 1.5 3.7 3.6 1.4 4.9 3.1 3.5 3.0 1.6 4.0 3.6 3.4 0.2 2.8 2.6 6.3 3.1 0.9 11.3 14.9 14.3 13.3 12.8 9.2 8.7 8.0 9.2 6.7 9.5 13.5 37.0 115.4 77.4 145.6 18.4 20.9 22.2 12.4 20.5 56.3 26.2 25.0 35.5 5.7 24.1 29.5 54.2 11.9 30.2 21.1 17.6 6.1 131.8 27.9 47.3 29.6 12.6 19.6 225.5 8.0 11.3 35.6 15.8 41.2 10.1 53.1 22.1 5.7 9.0 53.8 192.9 9.7 8.2 54.8 10.0 161.9 38.8 17.7 23.2 113.4 13.0 24.0 14.4 177.0 180.2 10.9 15.5 42.9 12.2 25.0 10.4 14.1 28.3 462.1 19.7 54.9 32.6 115.2 41.8 18.4 23.9 12.0 18.5 17.0 12.8 15.7 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 N4BP2 B3BP ENSG00000078177 "NEDD4 binding protein 2" Q86UW6 4 40056850-40158252 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 11.3" "Cell type enhanced" "Detected in many" "Horizontal cells: 72.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MOLT-4: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036770, HPA042607, HPA072549" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA036770: AB_10672477, HPA042607: AB_2678074, HPA072549: " "unprognostic (5.03e-2)" "unprognostic (3.42e-1)" "unprognostic (7.94e-3)" "unprognostic (1.15e-1)" "unprognostic (1.50e-1)" "unprognostic (3.99e-3)" "unprognostic (2.88e-1)" "unprognostic (1.01e-1)" "unprognostic (3.66e-2)" "unprognostic (2.65e-2)" "unprognostic (9.55e-3)" "unprognostic (4.49e-2)" "unprognostic (2.14e-2)" "unprognostic (1.24e-1)" "unprognostic (9.31e-2)" "unprognostic (6.85e-3)" "unprognostic (1.45e-1)" 1.0 0.7 1.4 2.5 1.2 4.1 2.9 1.8 1.6 2.5 1.7 2.2 2.4 3.4 1.9 1.8 1.8 1.6 1.1 0.7 4.2 1.5 5.8 1.6 3.6 2.1 1.7 3.0 4.2 1.4 1.2 3.6 0.7 2.4 2.2 2.2 3.5 0.9 0.7 1.9 2.2 0.8 1.4 1.9 1.9 1.8 4.0 11.3 3.5 1.0 4.1 2.1 1.4 0.5 2.0 2.0 12.0 1.9 0.8 3.8 9.5 2.2 2.5 1.3 2.7 3.9 4.0 10.7 4.3 2.1 2.2 1.5 7.7 2.4 3.0 3.4 2.3 4.8 1.5 1.8 1.9 13.0 11.2 4.3 3.3 2.1 4.6 0.4 3.3 10.0 10.8 4.5 2.5 1.9 26.8 6.4 6.0 1.6 1.7 15.4 14.1 2.5 1.0 4.7 4.7 8.3 2.2 1.6 2.1 7.8 1.5 3.8 4.5 1.5 7.3 0.9 1.7 7.4 8.0 7.3 1.4 4.8 3.0 5.1 0.8 0.4 1.7 0.9 1.8 1.2 2.3 1.3 1.4 1.7 3.4 1.9 0.2 8.2 0.9 6.5 1.1 0.9 1.4 1.2 1.8 1.6 0.7 4.2 2.1 1.7 0.7 1.4 4.0 0.5 9.6 22.4 24.4 19.2 18.2 12.0 14.3 5.1 18.8 33.0 12.3 11.2 12.3 11.5 13.2 22.0 27.1 44.2 36.7 9.0 0.0 6.0 4.7 17.6 15.1 11.4 19.3 22.5 16.5 12.6 12.9 15.5 12.2 20.7 5.1 36.1 6.8 20.7 12.4 72.3 47.2 17.1 10.2 16.3 24.6 4.3 9.9 24.0 7.2 36.5 17.9 12.4 27.8 44.2 3.1 11.4 10.8 3.8 36.0 12.4 7.3 3.6 8.7 22.6 13.1 17.9 6.3 22.0 24.3 13.0 13.1 27.0 28.4 30.4 8.5 9.2 NAA35 "bA379P1.1, FLJ21613, FLJ22643, MAK10" ENSG00000135040 "N-alpha-acetyltransferase 35, NatC auxiliary subunit" Q5VZE5 9 85941146-86025462 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021547 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "HPA021547: AB_1853505" "unprognostic (5.87e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-3)" "unprognostic (9.25e-3)" "unprognostic (2.37e-2)" "unprognostic (6.39e-2)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.86e-1)" "unprognostic (5.22e-3)" "unprognostic (1.56e-1)" "unprognostic (8.30e-2)" "unprognostic (1.09e-1)" "unprognostic (2.36e-3)" "unprognostic (1.88e-1)" "unprognostic (4.34e-2)" "unprognostic (9.18e-2)" "unprognostic (1.07e-2)" 7.7 12.2 6.9 6.3 7.3 6.6 9.3 9.8 7.0 8.9 8.2 11.1 8.6 9.4 7.8 10.9 8.4 5.7 8.8 6.9 7.2 8.4 8.7 7.1 6.2 6.3 6.0 9.9 10.8 9.4 12.0 7.4 6.2 9.7 10.5 14.3 10.1 6.8 17.4 9.1 8.1 7.0 6.4 6.5 8.8 15.4 8.4 7.3 10.4 13.2 7.2 9.0 9.1 8.9 25.4 15.8 17.7 13.5 9.8 13.1 24.8 15.5 15.1 16.1 13.1 12.4 15.7 8.4 8.5 15.4 13.1 34.9 15.0 18.4 16.8 22.3 13.1 21.6 19.9 14.6 16.6 30.4 17.6 13.1 15.2 17.0 24.6 12.4 14.0 15.6 25.3 15.6 14.9 14.6 15.7 16.0 17.8 28.0 18.2 14.4 26.9 12.6 17.3 20.4 16.7 15.5 17.6 15.8 13.6 17.0 11.9 11.7 14.0 11.2 12.4 16.9 15.0 22.3 29.1 5.7 16.3 12.5 10.2 1.7 2.5 5.1 3.4 2.6 4.3 9.5 3.5 3.1 3.0 9.3 4.6 3.4 1.3 3.5 1.9 2.2 3.1 2.6 6.9 7.3 9.8 7.0 6.9 7.2 6.3 6.0 6.2 6.4 8.4 8.9 14.6 3.2 14.1 58.4 16.8 16.3 20.2 19.0 19.9 25.5 18.0 13.1 23.3 18.6 22.8 11.0 22.9 22.6 14.9 20.2 1.9 19.7 8.7 29.4 18.6 14.3 20.9 14.5 51.8 25.8 18.9 13.6 16.3 22.5 12.0 32.9 9.3 9.8 12.2 21.9 58.7 14.5 30.5 11.0 8.4 5.3 9.3 10.7 14.2 52.5 12.3 18.7 14.4 44.7 68.8 18.3 16.6 11.7 17.1 22.0 12.0 8.9 33.7 36.6 13.1 21.4 24.7 56.7 36.3 17.7 16.6 31.1 15.8 24.4 16.6 19.2 NAB1 ENSG00000138386 "NGFI-A binding protein 1" Q13506 2 190646746-190692766 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 138.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002738 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 28: Keratinocytes - Keratinization" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "HPA002738: AB_1079447" "unprognostic (1.44e-1)" "unprognostic (2.65e-2)" "unprognostic (6.02e-3)" "unprognostic (4.04e-3)" "unprognostic (9.05e-2)" "unprognostic (9.45e-2)" "unprognostic (7.12e-3)" "unprognostic (6.41e-2)" "unprognostic (2.13e-2)" "unprognostic (1.79e-2)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.52e-1)" "unprognostic (7.23e-3)" "unprognostic (1.71e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (3.85e-2)" 29.3 20.3 19.4 23.5 16.7 18.6 34.8 50.4 23.5 28.1 7.4 22.8 15.8 32.3 50.1 36.3 27.5 28.0 28.5 18.7 9.7 19.9 37.8 22.8 26.8 13.4 13.2 26.0 17.9 23.5 21.1 26.4 14.9 18.5 25.6 41.4 20.7 20.9 8.0 66.7 17.1 25.2 14.9 19.8 37.9 26.0 13.8 21.2 37.9 17.2 26.3 31.2 24.2 25.9 35.5 25.8 65.0 22.6 24.5 42.7 111.0 35.5 55.7 26.4 29.8 62.8 38.4 39.6 40.6 28.3 48.9 88.4 37.4 45.9 51.8 126.1 31.0 46.7 96.3 30.2 15.8 19.8 22.4 24.6 70.4 55.9 17.1 37.4 41.5 23.9 46.3 33.2 40.6 17.4 28.7 20.0 22.8 38.4 35.2 35.0 46.7 15.9 19.3 34.5 57.9 46.9 41.8 13.9 37.3 82.8 11.4 30.6 29.0 54.5 43.0 31.0 21.6 25.7 30.3 29.5 57.3 17.6 43.7 0.0 1.3 0.6 1.3 1.1 1.9 0.7 1.3 1.7 0.9 0.4 1.4 1.5 2.9 2.6 3.7 0.8 3.3 0.8 19.4 16.7 50.4 23.5 18.7 9.7 13.4 13.2 14.9 14.9 13.8 25.9 24.1 6.4 21.2 14.0 5.9 102.0 23.1 24.6 31.3 26.1 19.7 19.7 18.2 11.5 29.8 12.9 12.5 4.3 9.2 11.4 3.9 10.3 1.4 17.5 10.8 30.1 14.4 12.0 37.2 8.0 11.1 25.2 21.4 23.4 20.3 14.2 44.6 25.7 6.7 6.7 21.2 17.5 14.2 17.3 77.4 3.2 13.4 20.7 39.2 24.4 10.6 12.4 11.3 29.1 28.3 10.2 26.3 14.7 14.9 30.5 4.8 5.1 22.3 15.5 46.0 24.6 39.2 1.7 27.3 55.7 138.9 1.2 16.7 7.3 16.0 29.9 NAIF1 "bA379C10.2, C9orf90, DKFZp762G199" ENSG00000171169 "Nuclear apoptosis inducing factor 1" Q69YI7 9 128061233-128068206 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054898, HPA064931" Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA054898: AB_2682633, HPA064931: AB_2732725" "unprognostic (7.09e-2)" "unprognostic (5.92e-2)" "unprognostic (1.20e-2)" "unprognostic (5.56e-3)" "unprognostic (1.58e-1)" "unprognostic (2.17e-1)" "prognostic unfavorable (1.61e-4)" "unprognostic (1.60e-1)" "unprognostic (6.15e-2)" "unprognostic (9.41e-2)" "prognostic favorable (1.02e-5)" "unprognostic (3.08e-1)" "prognostic favorable (8.30e-5)" "unprognostic (8.48e-2)" "unprognostic (2.47e-1)" "unprognostic (6.67e-2)" "unprognostic (3.92e-2)" 2.0 2.4 1.2 1.8 1.4 4.3 1.8 1.2 1.6 2.1 1.3 2.0 2.0 2.2 0.7 2.6 1.8 1.0 2.0 1.2 1.2 1.7 2.6 1.6 2.6 1.4 1.2 1.7 2.4 1.8 1.5 1.6 1.3 1.5 1.2 0.7 2.2 1.4 2.7 2.3 2.3 1.4 1.1 3.2 2.1 3.4 1.6 2.4 1.7 1.9 2.2 1.6 1.8 1.2 5.1 4.4 2.7 7.0 2.5 2.2 6.1 3.8 2.3 3.2 2.6 3.5 4.0 6.2 3.3 2.4 4.5 3.8 2.8 2.9 2.6 19.1 3.8 4.6 5.4 2.0 4.1 6.4 12.5 2.0 3.4 2.5 4.0 2.6 2.9 6.9 11.0 3.9 3.0 5.9 6.2 7.7 3.0 6.9 7.4 5.9 4.3 5.7 2.5 3.1 3.9 4.5 3.8 5.2 4.0 2.0 4.0 6.3 2.0 3.8 11.8 3.2 4.5 6.3 14.0 4.1 3.6 4.1 5.1 0.0 0.7 1.2 0.5 0.6 0.4 0.3 1.1 0.7 0.7 0.9 0.7 0.6 1.5 0.5 1.0 0.5 0.3 0.5 1.2 1.4 1.2 1.6 1.2 1.2 1.4 1.2 1.3 1.1 1.6 1.2 5.6 0.0 3.0 2.0 5.4 4.8 4.6 3.9 4.6 4.0 3.9 2.8 4.2 4.3 3.4 5.5 0.0 5.8 6.6 6.3 3.9 3.5 8.7 2.6 3.5 6.4 5.4 0.8 1.0 6.6 5.7 3.1 1.5 3.2 8.2 3.7 7.1 2.4 5.7 10.1 0.9 4.0 0.0 7.0 3.6 10.9 6.2 3.1 0.0 0.0 5.1 4.6 7.2 2.0 0.7 3.7 5.1 3.0 3.4 3.3 7.3 4.2 1.8 5.0 0.0 4.2 3.5 15.1 7.8 5.0 3.8 4.7 4.0 4.4 3.6 2.9 NAMPT "PBEF, PBEF1" ENSG00000105835 "Nicotinamide phosphoribosyltransferase" P43490 7 106248298-106285966 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Biological rhythms, Pyridine nucleotide biosynthesis" "Cytokine, Glycosyltransferase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 580.0;Langerhans cells: 1123.7;Macrophages: 947.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 7 "neutrophil: 279.2" "Lineage enriched" "Detected in all" 9 "granulocytes: 279.2" "Cell line enhanced" "Detected in all" "HHSteC: 387.5;U-87 MG: 434.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB034349, HPA047776, HPA057722" Approved Approved "Nuclear speckles,Cell Junctions" "Secreted to blood" NA NA 2140000 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Cell Junctions" "CAB034349: AB_2251220, HPA047776: AB_2680151, HPA057722: " "unprognostic (2.87e-1)" "prognostic unfavorable (4.78e-4)" "unprognostic (5.90e-3)" "unprognostic (1.63e-2)" "unprognostic (1.50e-2)" "prognostic unfavorable (8.81e-4)" "unprognostic (2.15e-1)" "unprognostic (2.74e-2)" "unprognostic (2.74e-1)" "unprognostic (3.30e-1)" "prognostic unfavorable (1.51e-4)" "unprognostic (3.02e-1)" "prognostic unfavorable (2.49e-6)" "unprognostic (6.83e-2)" "unprognostic (6.96e-2)" "unprognostic (7.76e-2)" "unprognostic (6.44e-3)" 308.5 74.2 14.4 360.5 15.6 312.5 103.3 15.2 35.4 47.3 21.7 62.5 38.5 38.6 6.9 228.2 107.6 113.7 103.1 15.2 20.9 82.9 317.9 218.5 23.2 75.7 24.9 58.4 80.9 25.9 30.1 87.3 30.3 70.1 30.3 17.2 126.0 13.4 135.9 54.1 55.9 48.0 21.3 88.2 102.4 11.7 46.3 15.6 42.2 44.4 39.9 283.3 86.7 21.5 103.6 41.0 14.6 16.8 85.8 95.0 34.4 26.1 194.7 57.0 90.6 25.7 38.7 77.7 78.8 32.1 131.5 58.2 38.8 88.1 93.8 50.5 51.7 35.8 17.2 22.6 387.5 61.3 49.4 94.8 94.2 114.9 115.0 70.6 187.3 32.0 70.5 225.6 68.1 49.4 58.1 19.4 36.6 33.6 59.7 25.8 30.4 147.6 46.2 60.8 33.4 19.3 46.0 61.1 107.9 43.0 25.4 9.4 168.2 75.6 52.9 105.9 51.9 212.1 142.7 115.7 434.3 69.3 105.6 39.6 6.5 16.0 1.8 21.8 2.4 3.9 2.2 2.7 7.0 3.4 2.8 2.2 279.2 4.4 30.5 5.5 7.1 4.8 14.4 15.6 15.2 35.4 15.2 20.9 75.7 24.9 30.3 21.3 46.3 21.5 323.8 131.4 245.7 12.1 78.0 207.6 321.0 105.7 169.0 23.8 184.2 132.0 94.8 197.3 161.4 42.3 12.5 26.2 67.5 105.8 46.9 320.6 12.2 128.0 160.8 192.8 25.1 29.5 25.3 141.3 58.9 239.6 132.0 296.5 188.4 18.8 159.5 580.0 107.0 40.4 28.8 51.9 63.1 390.3 1123.7 6.9 40.4 947.3 161.9 46.9 102.7 22.6 9.2 12.1 22.4 138.1 49.7 31.2 93.7 364.0 112.8 50.7 94.1 30.8 26.3 264.6 185.6 30.5 65.8 98.3 207.8 25.3 110.3 38.4 79.4 334.5 NAP1L2 "BPX, MGC26243" ENSG00000186462 "Nucleosome assembly protein 1 like 2" Q9ULW6 X 73212299-73214851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.4;Excitatory neurons: 34.3;Horizontal cells: 18.5;Inhibitory neurons: 33.7" "Cancer enhanced" "Detected in many" "prostate cancer: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 16.6;Karpas-707: 14.1;NTERA-2: 18.1;U-2197: 14.6;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054050, HPA057065" Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA054050: AB_2682357, HPA057065: AB_2797258" "unprognostic (1.12e-1)" "unprognostic (6.64e-5)" "unprognostic (4.22e-2)" "unprognostic (9.64e-4)" "unprognostic (1.78e-1)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (8.51e-3)" "unprognostic (1.76e-2)" "unprognostic (2.66e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.53e-2)" "unprognostic (1.54e-2)" "unprognostic (6.95e-4)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.45e-2)" 2.1 6.0 22.7 2.2 24.4 0.5 3.1 28.4 60.4 4.2 4.6 3.4 0.9 5.1 8.2 2.6 4.0 2.3 7.9 28.8 27.0 8.3 1.0 2.3 3.2 18.5 15.4 8.9 2.5 12.1 14.5 0.0 17.9 11.0 2.9 19.1 3.2 5.8 1.3 5.2 2.2 4.7 12.1 4.2 2.2 2.1 15.7 1.7 8.5 2.9 1.6 2.9 2.6 25.7 0.0 4.8 0.1 9.4 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.3 0.0 16.6 0.0 8.9 1.0 3.4 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.8 0.4 1.3 0.2 2.4 0.1 0.3 6.6 0.4 14.1 0.0 1.7 5.9 0.0 18.1 0.0 8.4 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 1.1 0.0 3.5 1.8 0.0 0.1 0.0 10.3 14.6 1.2 6.6 31.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.3 1.2 0.8 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.0 1.0 0.5 22.7 24.4 28.4 60.4 28.8 27.0 18.5 15.4 17.9 12.1 15.7 25.7 1.0 0.0 3.0 8.5 0.9 6.4 6.2 1.0 8.0 24.4 0.7 2.9 11.1 2.8 0.8 12.9 0.0 0.0 2.9 1.8 13.7 1.1 0.0 0.0 0.2 3.1 7.2 0.0 34.3 0.2 0.0 4.1 1.1 0.1 4.5 0.2 3.6 0.7 0.1 18.5 33.7 0.4 0.0 0.3 0.0 0.4 0.3 0.1 0.0 9.4 0.0 13.7 0.0 9.5 9.1 0.8 0.5 0.4 1.9 3.3 0.0 3.3 0.0 9.9 0.0 5.5 4.0 0.2 0.1 2.6 3.0 0.0 3.5 0.2 0.5 1.0 NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Approved "Plasma membrane" NA NA 8800 "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA008208: AB_1854305, HPA011389: AB_1854306" "unprognostic (1.23e-1)" "unprognostic (7.64e-3)" "unprognostic (6.96e-2)" "unprognostic (1.53e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (1.46e-3)" "unprognostic (5.85e-2)" "prognostic favorable (8.14e-4)" "unprognostic (3.81e-2)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (6.96e-2)" 11.3 14.8 18.4 9.7 18.6 7.2 11.8 21.1 25.3 10.5 13.9 11.9 9.3 10.7 12.0 12.1 11.0 13.4 19.9 25.9 20.8 16.4 13.6 9.7 9.6 30.3 20.1 7.5 12.6 12.4 9.9 13.9 32.6 13.7 13.7 12.6 11.7 10.7 10.2 9.9 10.7 11.8 19.4 9.4 13.7 7.4 20.1 9.0 14.5 14.6 11.2 14.3 10.1 21.7 9.4 5.6 9.6 8.3 27.1 18.4 14.0 19.8 28.1 19.0 24.0 12.4 14.1 12.3 15.5 27.3 17.4 9.0 12.7 17.7 26.9 11.0 7.8 9.2 9.8 12.8 25.9 26.0 16.6 20.3 20.6 21.8 16.2 12.4 18.0 16.0 15.1 29.0 28.2 13.2 20.0 11.1 7.7 72.3 8.3 8.7 15.8 21.2 22.5 22.0 38.3 10.1 16.1 16.9 23.1 15.5 7.7 17.2 20.5 29.8 14.4 27.8 21.2 18.8 20.4 13.6 20.1 17.7 14.2 12.5 4.9 14.1 5.1 6.1 4.7 7.5 4.1 5.2 3.8 3.3 5.6 4.8 8.1 5.8 6.1 4.1 4.4 3.1 18.4 18.6 21.1 25.3 25.9 20.8 30.3 20.1 32.6 19.4 20.1 21.7 32.2 28.9 34.7 33.6 29.1 24.3 31.1 26.9 21.6 62.0 21.8 17.4 35.1 21.5 27.5 27.6 12.5 23.6 32.9 30.8 41.1 53.3 18.1 27.9 33.2 23.4 23.4 33.2 68.5 42.5 30.3 25.3 28.5 49.5 45.0 13.6 20.0 21.7 25.4 45.4 53.8 22.3 28.5 22.1 16.1 4.6 7.8 24.5 26.6 30.9 22.4 31.3 22.6 34.7 52.9 77.7 34.1 21.1 36.2 34.8 20.8 39.5 20.8 34.0 26.3 30.5 29.6 26.6 39.9 30.8 21.2 45.1 26.2 28.4 19.0 56.5 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCK1 "NCK, NCKalpha" ENSG00000158092 "NCK adaptor protein 1" P16333 3 136862208-136951606 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005063, HPA030766" Supported Approved "Plasma membrane,Cytosol" NA NA 17000 "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "CAB005063: AB_562169, HPA030766: AB_2673602" "unprognostic (7.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.98e-2)" "unprognostic (3.03e-2)" "unprognostic (1.06e-2)" "unprognostic (8.77e-3)" "unprognostic (4.24e-3)" "unprognostic (8.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.14e-5)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.64e-1)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (4.17e-2)" 34.4 17.9 12.8 26.2 13.0 32.0 28.6 17.0 15.3 27.3 20.4 27.7 15.3 23.7 17.0 38.7 20.4 20.1 20.2 12.9 14.6 16.1 30.9 27.0 41.8 14.2 14.3 23.3 17.2 24.2 13.7 30.7 14.2 21.4 27.8 18.4 24.6 19.2 27.5 30.2 15.8 23.6 12.8 28.8 18.4 19.6 13.9 52.9 26.9 29.1 44.5 29.3 36.2 15.8 50.1 22.0 28.4 23.4 65.3 62.7 31.5 36.6 65.3 41.8 43.4 32.3 49.9 49.0 74.9 43.0 54.5 37.9 40.3 37.1 54.3 35.7 16.3 43.0 31.1 25.4 106.0 31.3 28.2 57.4 47.3 40.8 80.0 41.9 64.4 46.1 26.3 42.7 44.2 28.2 71.8 25.3 26.8 45.6 27.6 37.6 26.4 47.6 38.9 34.4 19.8 19.2 66.5 28.1 62.2 34.2 42.0 33.8 32.5 27.1 17.1 38.8 21.3 42.2 36.6 62.5 27.8 27.6 29.3 61.1 22.3 24.7 32.8 50.5 33.6 13.9 25.7 33.7 24.4 14.2 20.8 24.5 12.8 21.6 26.4 9.4 27.6 23.6 12.8 13.0 17.0 15.3 12.9 14.6 14.2 14.3 14.2 12.8 13.9 15.8 58.6 9.6 15.9 25.5 41.6 74.8 77.1 225.1 79.6 20.1 23.7 19.9 11.1 27.1 144.3 9.2 6.2 45.4 54.0 29.6 15.6 50.4 11.6 27.9 31.9 61.4 13.8 17.5 28.6 27.3 52.7 42.8 9.2 31.2 9.5 14.9 31.8 37.5 48.3 25.2 37.9 17.7 46.8 36.6 62.8 8.9 44.1 38.0 42.7 70.3 49.6 20.2 88.6 42.7 36.9 37.9 25.3 26.7 36.2 98.0 15.6 23.9 75.7 14.6 13.1 24.9 32.1 55.2 36.6 66.1 83.3 61.0 70.4 21.8 18.8 142.9 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NCKAP5 "ERIH1, ERIH2, NAP5" ENSG00000176771 "NCK associated protein 5" O14513 2 132671788-133568463 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 34.8;lung: 11.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 262.8;Astrocytes: 478.6;Oligodendrocyte precursor cells: 774.6;Oligodendrocytes: 2156.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "AF22: 46.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034639, HPA044859" Uncertain Approved "Nucleoli,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoli "Golgi apparatus, Plasma membrane, Cytosol" "HPA034639: AB_10669678, HPA044859: AB_2679114" "unprognostic (2.54e-1)" "unprognostic (1.95e-2)" "unprognostic (2.30e-2)" "unprognostic (2.58e-2)" "unprognostic (2.49e-2)" "unprognostic (3.13e-1)" "unprognostic (7.07e-2)" "unprognostic (1.90e-1)" "unprognostic (1.96e-2)" "unprognostic (1.82e-2)" "unprognostic (1.46e-1)" "unprognostic (2.93e-1)" "unprognostic (1.06e-11)" "unprognostic (4.56e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.03e-1)" 1.9 1.0 9.6 0.5 31.3 0.0 3.0 18.6 12.3 1.2 2.5 1.2 2.2 0.4 0.6 4.0 0.4 0.7 2.6 9.5 14.5 4.1 3.9 11.4 1.3 23.4 28.6 2.4 0.9 0.6 0.6 2.6 22.9 0.8 1.0 4.7 2.1 0.3 0.5 2.1 3.2 0.4 10.1 1.7 1.7 1.1 28.6 0.8 1.1 0.6 1.0 0.5 2.0 34.8 0.0 2.2 46.2 0.0 0.1 0.4 0.2 0.7 8.3 0.7 0.8 0.0 0.1 3.6 0.0 0.5 0.5 0.2 0.3 0.7 2.5 0.0 0.3 0.0 7.1 0.0 0.0 0.0 0.0 0.5 3.8 4.4 0.6 7.2 0.8 0.0 0.0 0.0 1.3 0.5 0.0 0.0 1.1 0.3 1.4 0.4 0.0 1.9 1.1 1.1 0.2 1.4 0.0 1.7 2.4 0.4 0.7 0.0 2.4 0.3 0.4 6.7 0.1 0.2 0.0 1.3 0.4 0.0 0.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.6 31.3 18.6 12.3 9.5 14.5 23.4 28.6 22.9 10.1 28.6 34.8 6.0 262.8 13.3 478.6 0.6 8.9 0.7 1.4 15.4 179.6 14.5 10.8 16.8 0.0 28.6 1.8 41.7 0.1 0.1 5.3 3.9 0.3 6.8 1.1 1.1 2.9 3.6 0.0 16.4 0.2 0.2 6.8 7.7 1.4 1.3 0.0 0.7 6.3 0.6 33.7 41.3 5.4 10.2 7.9 32.2 3.3 26.4 6.2 1.8 147.1 4.1 56.9 0.0 774.6 2156.8 1.0 5.2 7.5 0.0 0.5 20.7 14.0 1.2 7.8 6.6 8.7 24.7 0.1 1.3 15.5 2.8 0.0 0.7 0.0 1.6 1.5 NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 121.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019267, HPA050005" Enhanced "Plasma membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "CAB019267: , HPA050005: AB_2680988" "unprognostic (1.55e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.79e-1)" "unprognostic (9.64e-3)" "unprognostic (5.50e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.20e-5)" "unprognostic (1.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" 18.6 17.7 25.5 6.3 28.5 5.9 17.0 16.4 47.6 14.9 2.4 13.7 10.0 12.9 11.4 11.1 16.3 12.4 37.5 26.3 23.0 19.3 14.3 16.5 8.5 23.1 16.4 31.1 11.8 121.9 20.1 11.1 22.5 17.5 9.8 11.3 14.1 15.8 12.6 19.8 12.5 11.7 13.1 11.5 11.6 16.4 23.7 6.3 13.6 10.0 7.0 12.6 14.6 29.3 20.9 18.0 18.0 18.6 24.0 14.5 25.0 20.5 22.8 22.2 28.2 26.6 12.4 15.3 10.9 12.2 25.4 13.8 23.2 27.1 12.7 17.3 28.3 27.4 73.2 21.5 20.9 18.8 29.6 14.0 23.3 30.9 19.3 25.2 12.8 19.1 9.5 19.8 18.1 15.3 17.1 15.8 21.0 20.6 31.5 8.6 8.3 25.8 12.3 21.2 18.7 15.1 21.4 19.9 17.4 16.3 17.7 22.7 7.2 19.0 21.3 22.8 27.5 17.7 14.1 17.0 21.7 24.6 29.8 0.6 2.9 0.1 2.1 3.4 1.5 2.9 2.4 2.4 3.6 1.4 3.5 2.4 0.2 3.4 1.8 5.2 2.9 2.9 25.5 28.5 16.4 47.6 26.3 23.0 23.1 16.4 22.5 13.1 23.7 29.3 15.9 0.0 6.9 7.2 2.9 2.5 3.7 8.1 1.8 9.2 3.8 5.5 17.0 5.7 4.0 1.8 12.5 9.6 4.5 10.8 5.9 7.0 2.4 4.7 5.5 8.1 8.4 4.8 11.8 4.6 10.5 5.4 6.6 5.8 5.7 7.6 23.6 6.4 8.6 11.8 10.9 6.0 6.1 6.5 6.1 2.5 18.3 6.4 1.8 1.9 4.5 3.5 0.0 2.5 8.3 7.5 6.2 47.4 3.9 2.3 13.8 7.6 3.9 6.3 13.1 4.0 6.4 5.6 18.4 2.8 1.7 8.2 3.3 8.6 8.7 2.3 NCOA1 "bHLHe74, F-SRC-1, KAT13A, NCoA-1, RIP160, SRC1" ENSG00000084676 "Nuclear receptor coactivator 1" Q15788 2 24491914-24770702 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Acyltransferase, Transferase" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 467.5;Excitatory neurons: 313.0;Inhibitory neurons: 421.8;Microglial cells: 341.9;Oligodendrocyte precursor cells: 459.4;Oligodendrocytes: 305.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 81.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019402, HPA070213, HPA070520" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane, Cytosol" "CAB019402: AB_2196189, HPA070213: AB_2686235, HPA070520: AB_2686276" "unprognostic (2.73e-1)" "unprognostic (5.82e-2)" "unprognostic (2.46e-2)" "unprognostic (9.89e-3)" "unprognostic (7.60e-2)" "unprognostic (2.36e-2)" "unprognostic (7.06e-3)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (1.72e-1)" "unprognostic (2.93e-3)" "unprognostic (1.16e-1)" "unprognostic (2.10e-2)" "unprognostic (7.15e-2)" "unprognostic (3.08e-1)" "unprognostic (1.29e-1)" "unprognostic (2.92e-2)" 16.6 15.1 24.0 13.3 25.4 17.3 17.3 24.6 28.2 18.6 13.6 15.9 20.9 19.0 12.8 17.6 15.7 14.0 15.3 29.6 19.5 18.9 15.0 16.0 15.3 17.7 19.2 26.6 17.4 30.0 16.6 17.1 16.0 15.2 16.6 47.3 16.0 20.2 33.4 15.7 18.9 19.0 19.5 16.3 12.5 19.9 21.8 26.1 11.8 36.1 16.3 14.9 15.5 22.3 14.1 10.3 17.7 9.2 19.2 17.3 26.9 7.4 14.7 9.1 8.1 9.6 5.9 10.2 3.1 13.5 17.4 3.4 10.7 6.3 9.8 48.6 15.5 36.5 4.1 4.1 12.0 16.9 29.1 27.9 9.4 8.8 7.1 11.3 9.4 12.9 22.6 16.5 14.0 9.4 15.1 6.0 8.5 8.2 6.8 11.8 81.5 5.1 9.9 18.9 16.2 12.8 17.1 10.2 7.4 9.3 12.3 8.6 10.2 15.2 11.9 10.5 7.5 18.8 17.5 17.2 8.6 10.5 7.7 10.6 3.3 7.0 3.4 2.6 3.8 1.6 3.0 3.8 2.5 2.4 2.9 3.5 13.8 3.5 2.9 5.2 3.7 2.0 24.0 25.4 24.6 28.2 29.6 19.5 17.7 19.2 16.0 19.5 21.8 22.3 41.0 38.5 31.5 467.5 16.7 30.5 11.6 7.8 14.2 96.5 32.3 26.7 41.9 17.2 22.8 14.7 52.1 13.1 47.0 39.0 7.9 16.5 29.7 14.6 37.6 34.9 25.2 29.9 313.0 26.6 18.1 39.8 19.9 28.4 20.2 52.9 36.8 22.8 17.9 62.2 421.8 20.7 20.3 29.8 30.3 7.4 47.2 37.7 19.6 341.9 34.7 66.7 78.2 459.4 305.8 20.1 33.5 43.2 14.3 15.7 30.4 12.5 16.9 71.6 39.5 116.9 34.4 37.7 37.6 16.6 31.0 5.3 33.4 27.2 24.1 21.7 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NDC1 "FLJ10407, NET3, TMEM48" ENSG00000058804 "NDC1 transmembrane nucleoporin" Q9BTX1 1 53765478-53838463 "Metabolic proteins, Predicted membrane proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA069751, HPA070882" Approved Supported "Nuclear membrane,Plasma membrane,Actin filaments" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Nuclear membrane" "Plasma membrane, Actin filaments" "HPA069751: AB_2686189, HPA070882: AB_2686320" "unprognostic (2.51e-1)" "unprognostic (1.93e-1)" "prognostic favorable (4.48e-5)" "unprognostic (6.96e-3)" "unprognostic (1.31e-1)" "unprognostic (1.36e-3)" "prognostic unfavorable (7.52e-7)" "unprognostic (3.46e-3)" "unprognostic (1.53e-2)" "unprognostic (2.01e-1)" "prognostic unfavorable (3.58e-4)" "unprognostic (9.27e-2)" "unprognostic (6.22e-3)" "unprognostic (3.00e-3)" "unprognostic (4.38e-2)" "unprognostic (9.24e-2)" "unprognostic (6.07e-2)" 5.4 5.2 3.4 9.5 3.5 8.4 11.1 3.6 4.1 5.7 3.6 11.9 8.9 6.5 7.4 7.7 7.5 4.6 4.5 3.6 3.4 6.9 7.8 4.7 15.7 3.2 3.3 5.9 4.7 9.5 1.7 8.0 3.3 4.8 14.2 6.0 4.2 5.2 4.3 7.3 8.2 7.1 3.5 5.6 6.4 7.5 3.5 14.2 6.8 5.2 18.4 7.1 4.2 3.9 61.6 31.2 42.8 43.7 15.5 15.5 49.3 40.9 31.0 63.8 51.1 47.5 40.4 119.0 26.2 18.6 51.2 72.0 73.2 43.3 89.8 29.8 50.9 58.5 42.9 40.5 14.3 95.3 31.9 9.4 17.0 62.9 37.5 18.6 39.1 44.2 67.7 16.9 35.6 22.2 47.2 38.2 101.0 52.2 49.9 52.0 68.4 66.0 29.8 41.7 25.4 32.2 36.5 71.5 35.9 45.3 55.3 50.2 22.7 32.9 32.6 45.5 74.9 17.9 48.8 84.7 27.3 71.6 42.2 0.0 2.3 1.5 3.0 5.0 4.7 3.6 2.8 2.7 2.6 2.8 5.3 4.1 0.1 3.1 3.3 2.3 3.4 2.4 3.4 3.5 3.6 4.1 3.6 3.4 3.2 3.3 3.3 3.5 3.5 3.9 4.4 6.4 6.3 12.4 8.7 10.1 6.4 9.0 12.0 4.5 10.1 6.3 8.1 4.3 5.4 5.5 2.1 11.5 5.9 7.9 0.0 8.5 2.3 5.0 5.6 6.1 0.0 19.4 13.8 9.1 20.2 6.3 8.6 4.6 7.6 21.5 5.3 7.1 11.8 3.3 11.0 10.3 16.2 8.2 8.9 2.1 2.8 7.1 7.2 13.1 4.7 3.3 3.1 11.6 19.4 7.0 5.8 3.4 20.1 8.9 2.9 4.5 5.5 2.9 6.6 6.3 15.7 11.8 14.3 18.2 8.5 6.8 6.7 4.3 18.2 6.5 NECTIN2 "CD112, HVEB, PRR2, PVRL2, PVRR2" ENSG00000130202 "Nectin cell adhesion molecule 2" Q92692 19 44846175-44889223 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 136.6;Ductal cells: 215.6;Exocrine glandular cells: 154.2;Glandular and luminal cells: 126.1;Pancreatic endocrine cells: 241.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 10.4" "Lineage enhanced" "Detected in many" "granulocytes: 10.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012759, CAB026138, HPA073459" Enhanced Approved "Nucleoli fibrillar center,Cell Junctions" NA Yes 5900000 "Cluster 52: Eosinophils - Transcription" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 7: Non-specific - Mitochondria" "Nucleoli fibrillar center, Cell Junctions" "CAB026138: , HPA012759: AB_1846227, HPA073459: " "unprognostic (3.30e-2)" "unprognostic (2.84e-1)" "unprognostic (1.07e-1)" "unprognostic (5.61e-3)" "unprognostic (7.45e-2)" "unprognostic (2.21e-1)" "unprognostic (1.66e-2)" "unprognostic (6.63e-2)" "unprognostic (2.85e-1)" "unprognostic (2.97e-1)" "unprognostic (6.93e-2)" "unprognostic (3.19e-1)" "unprognostic (1.60e-1)" "unprognostic (2.15e-1)" "unprognostic (1.61e-1)" "unprognostic (8.19e-2)" "unprognostic (2.05e-1)" 71.4 79.1 30.8 32.1 28.4 15.8 66.0 29.8 34.3 41.7 44.3 42.3 55.3 45.0 58.2 76.3 43.9 52.5 71.3 29.2 33.1 79.6 118.5 72.9 15.8 35.8 33.0 41.7 55.0 61.5 39.1 77.2 32.9 69.2 32.8 16.7 62.6 30.4 20.1 52.5 47.5 31.3 31.8 58.1 75.4 65.8 34.7 6.9 57.4 17.7 25.3 55.8 49.3 28.9 73.8 89.3 118.3 140.6 59.3 35.8 123.7 62.6 83.9 120.4 136.6 194.8 171.0 0.6 79.2 79.0 61.1 98.5 106.6 55.6 91.7 3.2 53.2 43.0 30.8 128.6 145.0 0.7 117.9 64.9 22.5 56.2 44.8 123.2 149.3 3.0 71.1 0.7 59.2 146.4 0.6 5.6 92.8 249.8 27.7 4.3 37.7 3.2 139.5 100.1 5.4 15.2 74.9 127.0 28.7 210.4 97.2 47.1 140.1 31.3 105.5 23.7 48.6 9.0 25.8 0.6 57.3 10.0 83.0 1.8 2.0 10.4 0.0 0.7 0.2 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.8 0.0 0.4 0.3 0.0 0.7 30.8 28.4 29.8 34.3 29.2 33.1 35.8 33.0 32.9 31.8 34.7 28.9 136.6 35.3 31.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 108.4 54.9 0.0 0.0 6.8 58.8 0.0 109.3 2.6 0.0 3.9 215.6 0.0 73.8 66.3 58.8 0.0 0.0 0.0 154.2 97.8 30.4 0.0 126.1 3.8 75.0 0.0 0.0 54.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.2 0.0 0.0 80.1 0.0 0.0 0.0 0.0 241.8 0.0 0.0 0.1 0.0 0.0 27.1 3.6 0.0 0.0 0.0 42.9 0.0 0.0 0.0 0.0 101.8 2.2 58.3 0.0 0.0 NECTIN3 "CD113, CDw113, DKFZP566B0846, nectin-3, PPR3, PVRL3, PVRR3" ENSG00000177707 "Nectin cell adhesion molecule 3" Q9NQS3 3 111070071-111275563 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 54.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 25.6;Syncytiotrophoblasts: 117.3;Theca cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 117.4;TIME: 170.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009869, HPA011038" Approved Approved "Cell Junctions,Cytosol" NA NA 41000000 "Cluster 45: Intestine - Brush border" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" Cytosol "Cell Junctions" "CAB009869: AB_2284699, HPA011038: AB_1079719" "unprognostic (3.76e-2)" "unprognostic (3.81e-3)" "unprognostic (1.74e-1)" "unprognostic (1.97e-2)" "unprognostic (1.02e-1)" "unprognostic (9.77e-2)" "unprognostic (3.26e-3)" "unprognostic (3.77e-1)" "unprognostic (7.58e-2)" "unprognostic (3.94e-2)" "unprognostic (5.33e-2)" "unprognostic (7.04e-2)" "prognostic favorable (9.82e-7)" "unprognostic (2.01e-1)" "unprognostic (1.97e-1)" "unprognostic (2.67e-1)" "unprognostic (1.05e-1)" 8.9 4.8 3.9 4.7 6.0 0.2 4.3 6.2 7.5 7.3 0.0 23.0 32.9 7.6 1.5 4.6 9.7 8.2 5.3 6.6 5.0 12.0 29.4 10.4 3.0 10.8 5.6 16.1 7.1 4.6 1.1 22.7 6.7 11.7 23.1 7.3 5.6 8.4 1.7 1.4 21.2 13.6 7.3 3.9 24.6 54.7 12.4 1.5 42.5 7.1 3.1 6.0 3.0 8.8 0.2 36.2 117.4 7.7 45.7 85.3 7.2 78.6 82.7 47.8 39.7 33.4 16.7 0.0 25.4 112.4 26.6 0.6 33.2 11.4 87.4 0.9 8.8 0.1 12.1 2.4 77.2 5.9 1.1 43.6 4.6 31.7 30.3 42.5 40.8 1.5 0.0 30.2 104.2 0.2 7.8 0.0 33.0 11.0 12.9 0.0 58.2 0.2 26.9 19.2 2.9 20.8 1.6 0.0 15.7 38.9 1.3 0.5 170.4 58.8 24.9 11.1 47.2 17.2 0.0 0.2 37.9 0.1 56.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 6.0 6.2 7.5 6.6 5.0 10.8 5.6 6.7 7.3 12.4 8.8 8.3 25.6 11.8 0.0 0.9 0.0 0.0 0.0 0.0 0.0 1.6 3.0 0.0 0.0 3.1 12.9 0.0 3.9 4.5 0.0 0.0 6.5 0.0 9.0 11.4 4.4 0.0 0.0 0.0 18.9 9.4 9.5 0.0 13.7 1.3 6.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 17.4 0.0 0.0 2.8 0.0 0.0 7.1 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 117.3 5.3 31.5 0.0 0.0 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NEDD9 "CAS-L, CASS2, HEF1" ENSG00000111859 "Neural precursor cell expressed, developmentally down-regulated 9" Q14511 6 11183298-11382348 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Growth regulation, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 323.2;Alveolar cells type 1: 471.1;Glandular and luminal cells: 337.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 137.3;HSkMC: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009689, CAB009720, HPA038768, HPA039270, HPA072955" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 8: Neutrophils - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009720: , HPA009689: , HPA038768: AB_2676196, HPA039270: AB_2676422, HPA072955: " "unprognostic (2.83e-3)" "unprognostic (2.33e-2)" "unprognostic (1.08e-2)" "unprognostic (6.93e-2)" "unprognostic (2.12e-1)" "unprognostic (1.16e-1)" "unprognostic (1.62e-1)" "unprognostic (9.54e-2)" "unprognostic (3.05e-2)" "unprognostic (2.09e-1)" "unprognostic (2.90e-1)" "unprognostic (1.64e-1)" "unprognostic (5.59e-3)" "unprognostic (2.25e-2)" "unprognostic (2.37e-1)" "unprognostic (2.41e-1)" "unprognostic (1.05e-1)" 94.7 8.6 8.3 23.3 8.1 8.6 64.2 6.4 12.3 26.6 14.4 30.7 15.5 19.2 17.5 14.5 22.7 31.4 32.7 7.7 6.4 33.8 20.7 91.9 25.8 8.3 7.3 8.3 17.1 9.5 8.1 69.2 8.5 22.4 30.2 9.8 26.7 29.8 27.2 20.6 38.1 25.8 7.4 25.2 23.5 6.9 9.7 22.2 25.6 12.0 22.2 34.5 15.3 7.9 4.4 29.0 26.4 0.4 17.7 2.3 27.7 6.6 8.2 12.2 22.4 9.3 1.9 9.2 137.3 14.7 1.5 12.6 36.0 13.5 15.8 4.1 1.0 0.8 4.4 62.3 8.3 10.1 0.4 67.7 4.0 7.9 1.3 4.4 21.0 0.8 0.1 7.6 27.7 1.3 5.8 4.0 4.1 34.6 2.9 1.6 0.7 5.4 6.1 39.8 0.6 4.8 1.1 31.2 55.5 29.3 2.3 7.7 53.8 8.2 14.3 0.8 16.5 7.8 34.8 11.4 0.2 7.9 36.6 24.2 13.3 37.3 18.3 28.5 14.7 10.9 12.2 17.5 14.1 12.3 6.4 9.9 80.9 12.3 50.6 8.7 12.1 17.1 8.3 8.1 6.4 12.3 7.7 6.4 8.3 7.3 8.5 7.4 9.7 7.9 323.2 471.1 135.1 11.1 34.9 60.5 235.6 83.5 98.4 4.7 43.1 38.0 14.2 50.1 89.0 44.1 25.0 56.3 45.9 103.4 9.8 62.0 8.2 244.8 24.8 148.1 108.3 2.5 18.2 19.8 42.6 37.2 107.6 337.0 64.5 15.7 86.7 21.6 14.7 10.1 11.3 108.4 12.2 29.8 28.9 4.3 7.5 51.4 24.9 34.7 15.4 84.1 64.9 8.0 4.9 69.1 43.6 29.0 34.8 66.1 100.5 26.7 64.4 12.4 26.3 8.8 30.0 2.1 1.1 11.4 20.6 42.8 59.4 37.2 46.6 90.3 NEO1 "HsT17534, IGDCC2, NGN, NTN1R2" ENSG00000067141 "Neogenin 1" Q92859 15 73051710-73305205 "Cancer-related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 231.8;Excitatory neurons: 124.5;Oligodendrocyte precursor cells: 120.1;Oligodendrocytes: 439.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009320, HPA027804, HPA027805, HPA027806" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 390000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB009320: AB_2150998, HPA027804: AB_10600771, HPA027805: AB_10601755, HPA027806: AB_10601006" "unprognostic (1.90e-1)" "unprognostic (2.38e-2)" "unprognostic (7.60e-3)" "unprognostic (3.76e-2)" "unprognostic (5.44e-1)" "unprognostic (3.83e-2)" "unprognostic (8.30e-2)" "unprognostic (2.31e-1)" "unprognostic (3.22e-1)" "unprognostic (3.30e-2)" "unprognostic (5.51e-2)" "unprognostic (8.05e-2)" "prognostic favorable (4.39e-4)" "unprognostic (1.51e-1)" "unprognostic (1.41e-1)" "unprognostic (1.33e-2)" "unprognostic (3.75e-1)" 9.6 7.4 28.9 8.9 43.8 1.5 16.7 38.1 31.4 18.2 10.7 46.0 27.3 19.6 9.9 11.5 21.9 19.6 7.8 29.4 29.2 23.4 8.7 15.9 3.9 34.6 38.0 24.8 17.2 41.8 6.7 1.7 35.6 33.0 55.1 19.5 18.3 36.0 30.9 37.5 26.5 23.3 28.7 5.3 22.9 13.5 36.6 7.2 18.2 24.8 6.2 10.5 9.6 60.0 8.9 42.9 50.1 33.2 29.6 8.6 12.5 3.3 4.1 8.2 1.7 6.4 42.8 2.5 4.9 9.4 30.8 1.9 35.3 19.5 3.5 15.8 26.0 29.0 0.5 6.0 8.6 0.8 0.9 21.3 35.4 1.6 16.2 9.5 0.0 22.3 0.2 53.9 2.0 26.8 10.5 0.7 47.9 6.7 3.6 23.9 26.8 5.8 15.8 23.7 22.7 32.1 40.2 17.6 20.7 39.9 18.6 5.3 0.1 38.0 19.9 12.5 9.3 22.8 45.2 6.2 8.2 8.3 10.9 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.2 0.3 0.0 0.0 0.1 0.1 0.3 0.2 0.0 0.0 0.0 0.1 28.9 43.8 38.1 31.4 29.4 29.2 34.6 38.0 35.6 28.7 36.6 60.0 3.1 9.6 10.4 231.8 2.3 14.1 8.2 20.7 13.6 15.7 14.2 18.2 6.9 21.5 11.4 22.0 14.6 0.5 4.8 55.6 1.9 11.6 3.3 14.4 13.4 3.4 60.1 3.0 124.5 6.4 0.8 14.6 20.9 24.6 0.0 11.8 5.7 8.9 0.9 10.1 72.8 51.2 10.2 1.2 2.7 7.1 31.7 1.2 10.6 62.8 0.1 12.5 2.1 120.1 439.4 9.9 40.0 62.8 2.6 11.5 39.6 15.5 12.7 21.9 6.6 22.2 10.2 11.8 20.3 14.7 25.4 0.3 6.0 3.1 60.5 7.2 NEU1 NEU ENSG00000204386 "Neuraminidase 1" Q99519 6 31857659-31862905 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Lipid degradation, Lipid metabolism" "Glycosidase, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 3.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 3.0" "Cell line enhanced" "Detected in some" "GAMG: 5.4;U-266/84: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015634, HPA021506" Approved Supported "Vesicles,Cell Junctions" NA NA 180000 "Cluster 1: Neutrophils - Mixed function" "Cluster 18: Non-specific - Mitochondria" "Cluster 16: U-266 - Nucleosome" "Cluster 7: Non-specific - Mitochondria" Vesicles "Cell Junctions" "HPA015634: AB_1854386, HPA021506: AB_1854385" "unprognostic (3.84e-2)" "unprognostic (7.47e-2)" "unprognostic (9.64e-2)" "unprognostic (4.65e-2)" "unprognostic (3.00e-1)" "unprognostic (4.42e-3)" "unprognostic (1.38e-3)" "unprognostic (8.58e-3)" "unprognostic (7.49e-2)" "unprognostic (5.21e-2)" "unprognostic (4.44e-3)" "unprognostic (1.27e-1)" "unprognostic (2.70e-2)" "unprognostic (6.22e-2)" "unprognostic (1.48e-1)" "unprognostic (2.12e-1)" "unprognostic (2.13e-3)" 23.9 57.2 0.7 0.4 0.8 0.0 22.4 2.5 1.2 21.2 1.2 25.1 0.7 19.5 0.0 14.9 16.8 1.0 22.5 0.7 0.6 43.7 29.9 28.9 0.3 0.8 0.5 20.3 35.9 0.3 33.0 0.2 0.8 26.5 0.0 1.6 38.6 0.0 21.3 20.1 24.3 0.1 0.3 25.3 29.8 8.2 1.0 0.0 31.8 0.0 0.0 23.2 16.2 1.7 0.3 0.2 0.8 1.4 1.8 0.4 0.7 0.2 0.2 0.3 0.3 1.5 0.6 0.7 0.4 0.1 5.4 0.3 2.2 0.0 0.4 2.5 0.3 0.6 0.9 1.2 1.4 0.9 1.8 1.0 0.2 1.4 0.7 0.2 0.6 0.9 1.1 1.2 0.5 0.3 0.6 0.0 0.6 0.5 0.4 0.9 0.4 0.9 1.0 0.4 0.7 0.4 0.2 0.3 0.7 0.9 0.9 0.5 0.7 1.1 0.8 0.7 0.6 3.7 9.6 0.9 1.7 0.4 0.4 1.3 0.3 0.4 0.2 0.3 0.1 0.2 0.2 0.1 0.2 0.6 0.2 0.3 3.0 0.3 0.2 0.3 0.2 0.1 0.7 0.8 2.5 1.2 0.7 0.6 0.8 0.5 0.8 0.3 1.0 1.7 65.7 25.6 46.3 5.2 57.0 34.3 48.5 45.0 39.9 26.4 87.7 55.8 29.0 51.5 54.8 47.8 25.0 62.8 100.5 83.7 9.8 114.2 0.8 29.3 53.5 42.8 113.5 4.6 6.3 59.6 57.8 73.8 32.6 60.8 67.9 17.4 30.7 34.5 170.9 10.1 7.6 39.9 79.3 63.0 65.9 1.4 27.7 93.0 71.2 9.4 25.8 48.8 9.2 5.0 4.0 34.4 88.1 23.3 81.7 89.0 115.0 59.9 29.2 32.7 26.3 60.8 43.7 5.4 10.0 29.3 41.6 197.0 81.7 40.3 41.1 34.6 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NF2 "ACN, BANF, merlin, SCH" ENSG00000186575 "Neurofibromin 2" P35240 22 29603556-29698598 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 77.1;Late spermatids: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003097, CAB005385" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "CAB005385: AB_2298548, HPA003097: AB_1079473" "unprognostic (3.27e-1)" "unprognostic (1.34e-2)" "unprognostic (1.34e-1)" "unprognostic (1.76e-2)" "unprognostic (3.14e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.61e-1)" "unprognostic (3.67e-2)" "unprognostic (2.16e-2)" "unprognostic (2.01e-3)" "unprognostic (4.66e-1)" "prognostic favorable (2.89e-5)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.24e-1)" "unprognostic (9.62e-2)" 8.8 13.6 19.7 8.4 17.2 8.0 7.6 13.6 28.7 8.9 10.7 10.8 6.2 11.1 6.2 13.4 8.6 5.3 21.4 27.3 13.9 17.2 10.5 9.3 6.4 14.4 18.1 8.5 12.7 27.4 9.5 4.6 14.3 9.9 5.4 7.3 8.5 6.7 22.8 10.2 8.8 8.0 14.3 9.9 10.0 20.9 17.6 9.3 11.1 19.1 7.1 9.3 7.7 16.6 75.8 36.7 12.2 74.3 21.5 22.0 7.7 57.3 37.9 74.1 53.7 32.7 18.4 21.1 50.4 69.9 48.9 27.1 25.1 37.8 52.0 31.9 12.5 26.8 24.4 26.4 22.4 35.1 28.6 20.1 16.4 53.3 51.0 21.8 47.7 13.7 12.0 18.7 64.5 35.1 21.4 16.6 8.3 16.9 20.4 24.2 56.8 18.8 68.5 37.3 17.0 11.6 36.0 24.5 14.0 9.4 14.9 15.4 92.7 101.1 109.6 44.8 112.5 30.0 26.7 25.5 27.0 14.5 68.5 10.0 10.0 4.2 15.5 14.7 13.1 8.3 11.5 10.4 15.1 8.6 9.7 9.2 2.3 13.2 21.0 10.2 10.7 12.2 19.7 17.2 13.6 28.7 27.3 13.9 14.4 18.1 14.3 14.3 17.6 16.6 8.1 6.4 20.1 14.7 9.4 14.1 11.6 9.8 8.6 16.3 14.5 9.0 23.1 18.6 10.0 14.7 10.4 11.7 12.7 9.0 21.5 40.0 77.1 14.5 17.7 13.2 13.1 13.9 27.5 24.9 6.7 12.5 7.7 15.2 22.9 12.2 11.7 14.4 13.5 30.3 27.1 7.9 6.1 14.7 7.5 121.4 7.2 10.2 8.8 18.7 8.6 19.1 14.4 17.6 16.7 40.1 14.5 12.4 14.7 13.6 10.5 30.1 8.6 9.6 6.6 13.7 15.6 29.5 8.1 15.5 14.3 3.8 12.9 17.4 11.2 9.5 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NFE2L2 NRF2 ENSG00000116044 "Nuclear factor, erythroid 2 like 2" Q16236 2 177227595-177392697 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002990, CAB020317, HPA043438" Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB020317: , HPA002990: AB_1079476, HPA043438: AB_2678482" "unprognostic (2.11e-1)" "unprognostic (3.12e-2)" "unprognostic (5.22e-2)" "unprognostic (1.41e-1)" "unprognostic (5.95e-2)" "unprognostic (3.90e-1)" "unprognostic (5.27e-2)" "unprognostic (9.58e-2)" "unprognostic (3.48e-2)" "unprognostic (9.86e-2)" "unprognostic (4.86e-2)" "unprognostic (1.83e-1)" "prognostic favorable (2.26e-4)" "unprognostic (1.97e-2)" "unprognostic (1.61e-1)" "unprognostic (1.26e-1)" "unprognostic (9.77e-3)" 87.0 73.6 64.8 65.4 83.9 58.9 78.3 74.9 86.7 83.2 78.7 83.4 100.1 92.6 97.2 257.0 88.5 97.7 77.6 66.5 71.6 143.5 176.6 88.5 50.4 82.0 77.5 137.3 47.3 60.4 58.4 80.4 84.5 72.7 85.8 68.2 79.7 90.5 64.4 162.3 82.9 91.8 70.4 69.0 176.9 65.2 75.7 68.2 130.4 65.9 93.8 160.7 108.7 91.8 53.1 57.3 52.2 56.4 181.4 190.2 61.7 91.8 124.9 81.4 90.5 75.9 97.9 52.8 93.8 102.8 148.4 96.9 65.1 136.7 111.5 40.8 41.1 65.9 95.9 156.3 231.2 39.3 60.6 134.0 314.5 115.5 169.3 184.4 80.9 39.7 72.7 91.4 111.8 49.8 42.3 101.9 58.8 277.2 58.9 34.0 46.5 54.6 120.9 182.1 69.0 45.0 202.9 64.8 216.6 147.8 49.1 105.0 119.9 80.4 54.5 89.5 54.7 70.1 44.7 43.1 81.6 43.3 159.4 130.6 89.3 55.4 55.2 84.3 62.9 61.8 64.0 57.0 100.4 51.9 101.2 66.8 103.2 68.1 83.0 38.8 66.6 66.0 64.8 83.9 74.9 86.7 66.5 71.6 82.0 77.5 84.5 70.4 75.7 91.8 193.3 157.0 93.5 66.3 143.3 295.8 241.8 448.4 306.7 61.3 90.0 113.7 67.9 117.2 247.0 154.5 16.7 113.2 249.1 120.7 393.2 154.5 81.4 238.1 126.9 139.6 75.6 58.0 25.3 170.8 34.5 206.6 170.7 279.9 212.7 141.5 120.0 93.2 88.1 57.2 26.6 73.5 321.4 111.6 569.9 39.0 287.7 266.0 96.0 88.1 170.6 191.4 55.6 63.8 113.0 128.3 91.8 214.0 118.8 150.5 94.9 85.0 205.9 48.4 39.5 211.8 152.4 66.1 32.1 617.9 315.4 186.2 150.6 153.5 119.6 225.2 NFKBID "IkappaBNS, IkBNS, TA-NFKBH" ENSG00000167604 "NFKB inhibitor delta" Q8NI38 19 35887653-35902303 "Predicted intracellular proteins, Transcription factors" "Inflammatory response" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 15.9" "Cell type enhanced" "Detected in many" "B-cells: 152.7;granulocytes: 90.3;Langerhans cells: 418.5;Macrophages: 89.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA054778 Uncertain "Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" Cytosol "Nuclear bodies, Plasma membrane" "HPA054778: " "prognostic favorable (6.01e-4)" "unprognostic (9.60e-2)" "unprognostic (1.00e-1)" "unprognostic (3.28e-2)" "unprognostic (1.51e-2)" "prognostic favorable (5.43e-4)" "unprognostic (4.21e-2)" "unprognostic (7.68e-2)" "unprognostic (3.83e-1)" "unprognostic (4.10e-2)" "unprognostic (1.47e-3)" "unprognostic (5.64e-2)" "unprognostic (6.83e-2)" "unprognostic (1.04e-1)" "unprognostic (5.21e-2)" "unprognostic (2.71e-2)" "prognostic favorable (8.34e-6)" 4.0 1.8 0.7 4.4 0.6 15.9 2.5 2.7 1.6 1.9 2.1 2.3 1.1 1.8 0.0 2.1 3.0 2.4 1.5 0.8 1.4 2.5 1.5 5.6 4.8 1.4 0.9 3.3 2.1 0.9 4.2 0.8 1.2 2.2 0.8 0.7 1.6 0.5 0.4 2.2 4.0 0.5 1.0 5.4 2.0 0.4 1.3 5.2 3.9 0.2 3.1 2.2 2.0 1.7 3.3 3.0 0.6 2.0 0.3 0.5 1.4 2.0 2.4 2.1 1.5 0.7 2.6 4.0 1.5 2.1 1.9 1.7 2.1 1.6 0.9 2.3 0.4 2.4 4.9 0.7 0.5 2.1 7.0 0.7 1.0 3.9 0.9 0.5 0.8 1.8 0.5 2.4 0.4 2.6 1.7 2.5 0.8 0.6 0.6 0.9 0.4 0.8 1.8 1.4 1.0 0.8 2.7 2.1 0.2 0.5 0.9 2.1 0.8 3.3 3.0 1.5 1.4 1.7 0.6 4.6 1.8 4.9 0.5 0.0 0.9 1.7 1.4 0.6 1.1 3.3 0.6 1.1 0.9 5.5 1.0 0.6 3.2 1.5 1.1 1.2 1.5 0.5 0.7 0.6 2.7 1.6 0.8 1.4 1.4 0.9 1.2 1.0 1.3 1.7 11.7 0.0 11.3 2.9 152.7 29.7 14.3 12.9 34.7 8.0 10.9 7.5 1.1 5.7 5.6 1.8 20.9 1.3 58.9 5.7 0.0 2.5 0.1 27.8 6.8 21.5 3.0 1.7 4.9 1.0 2.8 11.3 2.0 80.8 90.3 3.8 9.3 0.3 39.2 0.0 3.4 5.7 2.0 31.0 418.5 0.4 1.2 89.4 19.6 2.8 40.0 1.0 13.4 1.5 0.5 2.8 2.1 1.9 38.1 13.8 9.2 1.7 3.9 9.2 0.0 3.3 6.7 0.4 1.0 20.7 33.4 1.0 45.3 2.4 6.2 10.0 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.4;Basal squamous epithelial cells: 36.5;Ionocytes: 89.5;Leydig cells: 96.0;Muller glia cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Group enriched" "Detected in some" 7 "RH-30: 200.1;WM-115: 225.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" 36.8 20.7 4.1 8.2 12.1 0.4 20.3 17.3 63.6 13.1 1.4 16.8 2.4 12.0 4.0 6.5 20.2 9.4 40.9 3.2 25.1 8.0 22.8 2.9 5.0 16.9 15.2 4.1 10.9 1.3 10.5 14.7 15.1 19.1 2.4 45.1 21.2 7.6 4.8 15.9 8.0 8.2 10.9 23.0 7.9 7.7 17.2 2.0 28.9 1.3 3.9 15.3 13.2 27.8 0.0 0.1 6.3 10.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.1 0.0 2.1 0.1 3.4 4.8 1.5 4.6 0.0 0.4 0.7 0.4 0.0 3.8 0.4 0.3 0.3 20.9 0.3 0.6 1.5 0.1 0.0 0.0 0.0 0.1 29.5 0.6 0.0 0.1 3.8 0.0 0.2 3.9 200.1 0.2 0.0 0.0 1.9 1.3 0.1 0.0 14.0 7.4 0.4 0.2 0.0 0.1 3.4 0.6 10.2 0.2 0.3 0.1 0.2 1.9 225.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 4.1 12.1 17.3 63.6 3.2 25.1 16.9 15.2 15.1 10.9 17.2 27.8 1.2 0.0 0.0 0.0 1.1 3.6 33.1 52.4 36.5 4.8 2.4 10.9 0.7 0.0 3.8 0.0 4.2 0.5 4.0 0.0 0.0 0.1 0.7 0.2 0.6 1.3 0.0 0.0 0.1 0.0 0.5 7.3 0.5 0.2 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 89.5 0.0 3.1 2.9 96.0 0.7 16.0 0.0 0.0 151.7 0.0 0.0 6.5 0.0 0.0 27.8 1.0 3.7 0.0 0.1 1.7 7.0 32.9 1.7 12.9 0.4 0.9 1.8 1.7 0.1 2.3 0.4 0.0 2.9 NHS ENSG00000188158 "NHS actin remodeling regulator" Q6T4R5 X 17375200-17735994 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Inhibitory neurons: 264.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 12.7;RPTEC TERT1: 19.2;RT4: 12.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA031497, HPA076257" Uncertain Supported "Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA031497: AB_10610144, HPA076257: AB_2686789" "unprognostic (1.39e-2)" "unprognostic (3.34e-1)" "unprognostic (1.17e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.58e-1)" "unprognostic (1.69e-1)" "unprognostic (9.92e-3)" "unprognostic (3.27e-3)" "unprognostic (1.08e-1)" "unprognostic (1.78e-1)" "unprognostic (1.61e-3)" "unprognostic (2.54e-1)" "unprognostic (1.72e-2)" "unprognostic (1.07e-2)" "unprognostic (1.21e-1)" "unprognostic (8.83e-3)" "unprognostic (1.83e-3)" 3.2 4.1 2.9 1.3 2.4 0.4 2.8 0.0 4.2 6.1 6.8 4.1 0.8 4.8 2.8 1.8 2.7 1.6 0.9 1.8 2.5 5.1 0.2 1.1 0.5 3.3 2.8 3.5 0.5 0.3 2.8 2.6 3.0 3.4 1.6 7.8 2.0 2.7 0.4 2.3 1.5 2.5 1.7 1.0 2.2 2.5 3.8 2.2 2.6 0.7 0.5 4.0 3.7 0.9 7.9 3.1 5.5 0.0 0.1 0.2 8.7 3.5 2.4 1.5 0.8 0.3 1.5 0.5 12.7 2.4 7.5 6.8 3.5 4.4 2.2 0.1 1.1 0.0 5.4 0.0 0.0 0.0 0.0 0.7 3.1 0.1 6.8 6.7 0.0 0.0 0.0 0.0 0.8 3.8 0.0 0.0 6.7 3.6 2.0 0.0 0.0 0.3 19.2 12.0 1.4 2.8 9.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 8.0 0.1 8.4 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 2.9 2.4 0.0 4.2 1.8 2.5 3.3 2.8 3.0 1.7 3.8 0.9 0.6 3.2 0.0 22.5 0.0 8.3 10.6 4.6 8.6 11.4 2.0 2.4 1.7 0.0 14.7 1.8 22.9 6.0 0.1 1.3 5.9 0.8 0.9 12.4 20.1 3.5 4.2 0.0 40.1 2.2 5.4 6.1 3.6 25.0 0.0 0.2 0.7 0.0 1.4 3.3 264.4 1.9 2.0 4.6 2.6 2.3 16.8 2.4 3.6 40.3 5.0 11.9 0.0 14.1 8.1 6.8 2.4 31.2 0.0 7.0 0.9 7.8 8.2 18.9 6.6 2.0 11.9 0.3 0.6 5.1 3.8 2.6 0.9 4.5 4.3 12.8 NHSL2 ENSG00000204131 "NHS like 2" Q5HYW2 X 71910818-72161750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 101.2;monocytes: 57.7;Prostatic glandular cells: 90.5;Urothelial cells: 80.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 14.3;neutrophil: 15.6" "Group enriched" "Detected in many" 4 "dendritic cells: 4.1;granulocytes: 15.6;monocytes: 7.1" "Cell line enhanced" "Detected in some" "AF22: 25.2;EFO-21: 29.5;HUVEC TERT2: 27.8;TIME: 16.3;U-937: 20.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049771, HPA075115" Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA049771: AB_2680872, HPA075115: " "unprognostic (9.71e-3)" "unprognostic (1.96e-1)" "unprognostic (1.92e-1)" "unprognostic (4.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.50e-2)" "unprognostic (2.88e-2)" "unprognostic (5.72e-4)" "unprognostic (5.46e-2)" "unprognostic (3.36e-2)" "unprognostic (1.50e-2)" "unprognostic (1.91e-1)" "unprognostic (1.61e-2)" "unprognostic (4.27e-3)" "unprognostic (9.99e-2)" "unprognostic (7.76e-2)" "unprognostic (4.37e-4)" 4.7 1.3 8.1 3.0 9.6 2.2 3.2 11.8 6.6 3.2 12.3 4.9 0.8 3.2 1.4 3.1 2.3 4.3 2.2 6.6 5.9 1.1 0.9 3.4 0.8 1.5 9.1 1.6 0.6 1.6 2.6 2.2 4.6 3.5 1.9 0.3 1.5 4.8 0.8 1.4 1.7 6.9 0.8 2.8 1.9 2.4 6.9 1.0 2.7 2.4 0.9 3.7 2.3 0.0 0.4 0.6 25.2 0.1 0.3 1.0 0.2 0.9 4.7 0.1 0.4 0.1 0.0 0.2 29.5 2.6 0.1 0.0 1.6 0.0 0.6 0.1 0.6 0.1 0.1 0.0 0.1 0.1 1.4 0.5 0.0 0.9 0.0 0.1 27.8 0.1 0.0 4.1 0.2 0.2 0.1 2.1 4.8 0.0 0.0 0.1 1.4 0.0 0.1 2.9 0.6 5.7 0.0 0.0 0.0 7.1 0.1 1.7 16.3 0.0 1.6 2.0 0.0 0.1 0.0 0.1 1.1 20.5 0.0 5.0 7.1 14.3 2.0 4.7 1.9 0.0 1.0 1.7 4.1 0.0 0.1 0.2 15.6 1.0 3.7 0.0 0.1 2.3 8.1 9.6 11.8 6.6 6.6 5.9 1.5 9.1 4.6 0.8 6.9 0.0 29.2 0.0 1.9 1.0 7.3 0.5 101.2 0.0 0.6 0.9 5.0 3.7 19.6 21.5 0.0 1.8 0.0 17.9 10.1 2.0 0.0 0.2 4.7 3.3 2.8 32.9 1.2 17.3 7.8 0.7 24.3 15.2 0.5 9.0 7.6 0.9 51.0 19.0 19.1 0.0 5.8 3.7 0.0 49.0 0.5 7.4 31.7 19.7 1.8 19.7 57.7 1.5 32.0 5.5 1.1 0.6 3.1 21.4 2.8 90.5 7.8 2.9 0.0 0.5 26.3 39.7 12.6 2.7 3.7 0.3 0.3 24.9 17.0 2.9 3.8 80.7 NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 164.1" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.1" "Cell line enhanced" "Detected in many" "HDLM-2: 83.8;Karpas-707: 85.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA028172: AB_10599602, HPA028231: AB_10601886, HPA028657: AB_10601680" "unprognostic (4.61e-3)" "unprognostic (3.45e-2)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-3)" "unprognostic (9.01e-3)" "unprognostic (4.38e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (4.52e-4)" 18.2 7.8 1.4 38.9 1.6 8.8 24.0 1.5 1.9 14.8 3.1 104.7 8.5 24.2 6.2 61.2 22.1 27.7 164.1 1.5 2.0 3.3 2.7 18.1 11.3 3.9 2.4 4.9 85.7 4.2 2.1 6.2 3.1 59.6 15.9 0.8 100.6 43.1 60.9 8.8 18.5 41.0 2.8 12.3 58.9 1.9 2.2 12.2 15.3 41.2 17.3 105.8 14.6 3.2 42.0 0.5 0.2 0.1 28.0 42.2 1.6 21.1 42.9 17.7 22.3 0.0 17.3 0.0 13.6 54.2 4.6 46.0 2.4 1.5 28.4 83.8 3.2 17.5 8.2 0.0 65.2 57.2 19.1 39.1 65.3 52.1 62.4 12.6 0.1 6.3 4.2 85.5 0.5 0.2 1.9 10.0 11.1 0.0 4.3 13.3 9.9 0.8 24.5 0.8 2.3 2.1 0.4 0.1 29.9 7.0 9.0 17.9 3.3 35.0 0.1 6.3 43.5 71.1 30.2 8.7 68.8 23.4 35.3 20.4 3.6 10.9 5.1 2.1 4.4 1.0 4.7 5.0 5.2 0.3 0.4 1.8 72.1 5.7 0.8 0.5 11.9 2.2 1.4 1.6 1.5 1.9 1.5 2.0 3.9 2.4 3.1 2.8 2.2 3.2 20.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 692.7 0.0 0.0 0.0 0.0 0.4 52.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.2 24.7 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.4 27.4 0.0 0.0 0.0 NIBAN2 "bA356B19.6, C9orf88, DKFZP434H0820, FAM129B, FLJ13518, FLJ22151, FLJ22298, MINERVA" ENSG00000136830 "Niban apoptosis regulator 2" Q96TA1 9 127505339-127578989 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 606.7" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 73.6;Extravillous trophoblasts: 40.5;Hofbauer cells: 23.0;Syncytiotrophoblasts: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "classical monocyte: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021284, HPA021417, HPA023261, HPA024312" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 1500000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA021284: AB_1848373, HPA021417: AB_1848374, HPA023261: AB_1848375, HPA024312: AB_1848376" "unprognostic (3.05e-3)" "unprognostic (9.47e-2)" "unprognostic (1.14e-3)" "unprognostic (4.07e-2)" "unprognostic (3.80e-3)" "unprognostic (1.09e-1)" "unprognostic (3.14e-2)" "unprognostic (2.57e-3)" "unprognostic (1.40e-1)" "unprognostic (1.68e-2)" "unprognostic (1.17e-3)" "unprognostic (6.45e-2)" "unprognostic (3.75e-2)" "unprognostic (1.24e-2)" "unprognostic (1.31e-1)" "unprognostic (8.40e-2)" "unprognostic (8.20e-3)" 48.7 107.5 26.7 36.6 24.7 27.3 42.0 25.2 24.5 96.0 45.3 74.6 50.8 38.9 12.6 606.7 39.4 39.6 39.4 22.7 35.0 72.3 16.7 121.9 6.6 48.9 34.3 31.6 142.6 26.2 34.0 84.8 36.3 66.5 30.3 2.7 142.1 32.2 13.6 111.3 53.9 22.0 39.7 32.2 83.3 11.0 34.7 5.6 110.6 11.3 53.6 68.4 189.6 31.9 134.0 149.8 29.9 39.3 87.9 170.1 138.2 259.1 238.5 140.1 86.4 48.2 143.7 0.4 100.4 295.5 172.9 217.5 25.9 192.2 45.9 25.2 27.5 22.8 218.9 50.4 173.1 1.0 62.0 187.3 118.3 231.4 80.8 256.8 213.6 8.4 43.5 1.2 269.8 157.3 1.6 37.6 30.9 228.0 194.4 16.0 99.9 70.1 120.5 105.6 47.4 22.1 212.3 149.0 93.4 42.1 98.2 7.5 279.9 143.1 62.4 182.2 218.0 2.5 5.1 0.6 403.3 21.6 271.1 0.2 1.1 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 26.7 24.7 25.2 24.5 22.7 35.0 48.9 34.3 36.3 39.7 34.7 31.9 12.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 73.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 40.5 4.2 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 120.9 0.1 0.0 0.0 0.0 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NINJ2 ENSG00000171840 "Ninjurin 2" Q9NZG7 12 564296-663779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 45.1" "Cell type enhanced" "Detected in many" "Adipocytes: 29.8;Alveolar cells type 2: 39.9;Erythroid cells: 35.4;Hofbauer cells: 30.7;Kupffer cells: 38.3;Oligodendrocytes: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 153.5;MOLT-4: 263.8;THP-1: 54.4;U-698: 49.3" "Low region specificity" "Detected in all" "HPA058980, HPA067226" Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 70: Brain - Nervous system development" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Endoplasmic reticulum" "Nucleoplasm, Plasma membrane, Centriolar satellite, Cytosol" "HPA058980: AB_2683869, HPA067226: " "unprognostic (1.16e-1)" "unprognostic (2.19e-1)" "unprognostic (9.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.37e-1)" "prognostic favorable (5.31e-4)" "unprognostic (5.72e-3)" "unprognostic (1.90e-3)" "unprognostic (4.60e-2)" "unprognostic (4.98e-3)" "unprognostic (5.88e-2)" "unprognostic (5.12e-2)" "unprognostic (2.68e-2)" "unprognostic (9.05e-2)" "unprognostic (1.03e-2)" "unprognostic (3.51e-3)" "unprognostic (1.23e-1)" 20.6 1.8 21.0 11.3 30.8 38.3 16.5 25.9 29.6 7.8 14.5 5.7 5.2 4.3 2.5 9.6 4.1 5.3 12.2 21.8 23.7 2.1 18.7 36.8 14.8 30.5 26.7 1.0 1.9 0.8 1.5 4.4 28.5 4.3 4.9 0.5 7.4 2.9 38.2 11.3 6.4 5.5 23.9 13.3 4.2 5.5 26.0 8.8 4.0 12.8 11.2 8.5 6.5 45.1 1.7 0.4 0.1 1.8 0.3 0.6 2.9 0.2 0.0 0.0 0.1 3.1 11.8 0.0 0.6 6.1 1.7 0.2 0.2 0.0 0.0 8.6 0.1 153.5 34.2 1.9 0.0 4.3 6.1 2.2 0.2 0.0 0.0 0.0 3.1 3.2 9.0 25.5 0.1 0.1 263.8 8.5 2.6 0.1 0.0 6.8 0.2 0.8 2.7 0.0 0.1 0.0 28.3 0.2 0.0 0.3 0.3 54.4 0.7 0.0 1.5 9.8 0.2 0.1 4.2 49.3 0.4 28.5 0.1 6.7 58.1 48.3 32.8 47.2 9.8 18.8 36.2 34.9 49.9 17.7 7.7 16.7 112.9 21.4 39.4 26.2 157.3 33.4 21.0 30.8 25.9 29.6 21.8 23.7 30.5 26.7 28.5 23.9 26.0 45.1 29.8 22.4 39.9 0.3 5.3 5.7 0.3 2.5 6.2 0.0 1.3 1.3 1.5 1.5 8.7 0.0 0.0 2.6 8.9 2.1 1.9 0.2 3.1 5.5 1.6 9.4 4.2 35.4 1.7 0.0 3.9 13.5 1.1 1.2 2.5 0.4 4.2 11.2 30.7 0.0 1.0 3.5 0.0 38.3 7.8 3.1 8.1 18.0 7.2 11.2 12.4 0.2 7.2 3.5 109.7 0.8 2.6 4.1 8.1 0.1 2.1 0.2 5.0 0.1 0.0 1.3 1.6 3.3 3.1 7.6 5.5 0.8 12.5 0.1 3.1 0.2 NKTR p104 ENSG00000114857 "Natural killer cell triggering receptor" P30414 3 42600655-42648735 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022120, HPA051576" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 42: Non-specific - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA022120: AB_1854513, HPA051576: AB_2681540" "unprognostic (2.73e-3)" "unprognostic (3.11e-1)" "unprognostic (2.33e-1)" "unprognostic (2.06e-1)" "unprognostic (5.27e-3)" "prognostic favorable (1.26e-4)" "unprognostic (4.62e-2)" "unprognostic (5.65e-2)" "unprognostic (4.02e-2)" "unprognostic (1.61e-1)" "unprognostic (5.33e-2)" "prognostic unfavorable (6.01e-4)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.82e-1)" "unprognostic (4.57e-1)" "unprognostic (1.40e-1)" "prognostic favorable (1.05e-5)" 17.4 19.2 16.4 17.6 18.7 46.5 19.3 22.3 17.1 28.4 17.9 17.7 13.2 18.4 22.4 17.0 23.0 11.4 17.8 15.0 20.3 18.2 21.1 23.9 22.1 20.5 16.4 29.0 22.1 10.6 36.5 11.1 17.6 23.2 13.4 41.3 17.5 10.5 19.5 32.6 25.4 10.7 14.0 36.7 16.3 18.0 18.2 15.4 25.4 10.4 20.0 18.3 22.6 27.8 15.1 7.7 32.3 15.6 16.6 19.3 14.9 22.8 6.8 9.9 12.9 14.7 13.3 25.9 10.7 9.1 9.0 12.6 16.1 8.4 19.2 11.0 13.1 31.4 30.5 24.6 7.3 25.4 19.9 9.6 12.2 18.4 10.5 19.1 17.4 7.1 30.3 20.2 18.6 6.9 17.8 35.5 23.1 7.6 12.3 17.3 12.0 10.5 15.7 12.7 9.4 8.5 24.1 11.1 4.8 16.3 17.5 17.8 28.0 18.0 13.1 21.4 23.2 17.2 21.7 17.7 10.1 30.0 11.3 7.8 3.6 7.5 5.7 4.6 5.3 5.5 5.6 4.9 2.9 5.3 5.6 4.9 5.3 7.0 6.8 5.1 5.3 2.3 16.4 18.7 22.3 17.1 15.0 20.3 20.5 16.4 17.6 14.0 18.2 27.8 221.8 109.0 141.4 169.4 129.5 59.0 60.3 57.8 66.0 200.0 76.3 69.8 68.7 65.8 73.2 88.3 246.0 72.5 156.0 60.3 17.6 47.3 23.9 114.4 125.5 166.2 71.8 76.6 143.5 38.8 51.1 83.3 86.6 132.4 96.8 210.0 110.7 58.6 45.9 132.9 170.0 70.2 61.1 53.8 70.2 21.8 167.7 78.9 51.6 194.9 97.4 101.9 163.7 180.0 267.2 47.6 59.2 134.3 131.3 77.5 106.8 17.0 53.3 279.9 92.1 103.5 88.9 246.2 186.1 42.4 57.3 31.3 164.4 104.5 75.0 54.2 NKX2-8 "Nkx2-9, NKX2.8, NKX2H" ENSG00000136327 "NK2 homeobox 8" O15522 14 36580004-36582614 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;esophagus: 2.6;testis: 7.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.3;Basal squamous epithelial cells: 6.8;Late spermatids: 2.1;Oligodendrocytes: 2.6;Prostatic glandular cells: 2.1;Squamous epithelial cells: 3.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;PC-3: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062879 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Plasma membrane" "HPA062879: AB_2684892" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (2.27e-1)" "unprognostic (3.45e-4)" "unprognostic (2.36e-1)" "unprognostic (8.34e-2)" "unprognostic (7.80e-2)" "unprognostic (3.66e-1)" "unprognostic (3.11e-1)" "unprognostic (8.39e-3)" "unprognostic (4.60e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" 0.0 0.0 0.4 0.0 1.1 0.0 0.0 1.2 0.5 0.1 0.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.3 0.0 2.3 1.3 0.0 0.0 0.1 1.1 0.0 2.4 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 7.9 2.1 0.0 1.4 0.0 0.0 0.0 0.0 4.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 1.2 0.5 0.2 2.1 2.3 1.3 2.4 2.0 2.1 4.4 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.9 6.8 0.0 1.0 1.1 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 3.4 0.4 0.0 0.0 0.0 0.0 0.4 NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174286644 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;retina: 13.8" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1484.7;Inhibitory neurons: 1700.0;Oligodendrocyte precursor cells: 4004.1;Oligodendrocytes: 1261.9" "Group enriched" "Detected in some" 9 "glioma: 3.8;melanoma: 2.2;renal cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 25.9;HUVEC TERT2: 24.9;RH-30: 26.2;WM-115: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA NA 82000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear bodies" "CAB033261: AB_2151659, HPA006572: , HPA006680: AB_1854400" "unprognostic (2.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.08e-5)" "unprognostic (7.52e-5)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (3.21e-3)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (4.08e-2)" "unprognostic (8.81e-2)" "unprognostic (2.41e-3)" "unprognostic (5.37e-2)" 2.0 1.0 12.6 0.5 10.8 0.0 0.7 31.0 12.1 3.1 0.0 2.0 0.2 2.1 2.5 2.5 3.0 1.6 3.2 12.5 15.2 2.9 0.0 0.4 0.2 5.3 5.4 1.3 0.8 0.7 1.8 0.5 4.0 2.2 0.9 13.8 0.3 3.0 0.2 0.3 0.6 2.7 4.4 0.0 0.8 7.0 20.5 0.2 0.9 1.0 0.1 2.9 1.3 7.2 0.1 0.0 6.1 0.0 11.8 12.4 0.0 5.2 12.8 0.6 0.8 0.0 0.5 0.0 0.2 25.9 4.7 0.0 3.7 0.0 1.3 0.0 6.0 1.7 0.1 0.0 0.0 0.0 0.0 9.7 0.1 0.0 0.0 10.0 24.9 0.0 0.0 1.7 0.1 0.0 0.0 0.0 7.2 0.0 1.7 0.0 26.2 6.4 4.7 0.1 2.5 1.7 0.0 0.0 12.3 1.1 0.6 0.0 3.1 13.5 1.3 9.9 11.6 11.7 0.0 0.0 4.6 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 10.8 31.0 12.1 12.5 15.2 5.3 5.4 4.0 4.4 20.5 7.2 0.3 0.0 0.5 66.6 0.0 0.8 0.4 0.0 0.6 14.3 0.1 0.0 4.4 0.0 0.0 3.7 4.2 0.3 0.0 0.0 0.0 0.3 55.9 0.6 12.4 0.8 0.0 0.0 1484.7 0.0 0.2 8.2 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1700.0 0.0 0.0 0.0 0.3 12.5 25.7 0.4 14.2 60.9 0.0 24.9 0.0 4004.1 1261.9 0.1 0.0 14.3 0.0 2.6 0.0 8.5 0.0 10.3 6.6 2.9 2.1 0.4 1.6 0.1 0.9 0.1 0.1 1.6 0.0 0.3 NLGN3 "ASPGX1, AUTSX1, HNL3, KIAA1480" ENSG00000196338 "Neuroligin 3" Q9NZ94 X 71144831-71171201 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Asperger syndrome, Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.1;seminal vesicle: 12.5" "Cell type enhanced" "Detected in some" "Astrocytes: 19.6;Inhibitory neurons: 12.7;Oligodendrocyte precursor cells: 92.0;Oligodendrocytes: 43.7;Peritubular cells: 17.3" "Cancer enriched" "Detected in many" 19 "glioma: 37.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.7;NTERA-2: 5.3;SH-SY5Y: 2.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003183, HPA004066" Enhanced Supported "Golgi apparatus,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Cell Junctions" "HPA003183: AB_1079469, HPA004066: AB_2732397" "unprognostic (4.06e-2)" "unprognostic (1.77e-1)" "unprognostic (1.59e-2)" "unprognostic (2.38e-2)" "unprognostic (2.42e-1)" "unprognostic (3.87e-1)" "unprognostic (6.52e-2)" "unprognostic (1.63e-1)" "unprognostic (7.10e-2)" "unprognostic (1.17e-1)" "unprognostic (1.94e-1)" "unprognostic (6.18e-2)" "unprognostic (4.27e-9)" "unprognostic (4.28e-2)" "unprognostic (1.90e-1)" "unprognostic (2.22e-5)" "unprognostic (9.01e-2)" 0.5 6.6 10.1 0.8 8.5 1.4 0.4 6.4 11.1 1.9 0.0 1.8 0.2 2.7 6.4 0.6 4.3 1.4 1.1 10.3 10.2 0.3 0.1 0.6 0.4 7.3 7.0 4.4 0.3 0.5 1.0 0.6 4.8 6.0 0.5 1.9 0.6 12.5 0.1 0.7 0.7 1.9 5.5 0.6 0.6 2.6 7.3 0.4 0.4 0.4 0.2 0.7 1.2 9.7 0.0 0.5 6.7 0.2 1.6 0.6 1.2 0.0 0.0 0.0 0.1 0.1 0.3 0.5 0.5 0.1 0.0 0.1 0.2 0.0 0.1 0.4 0.9 0.4 0.4 0.0 0.0 0.1 0.4 0.4 0.1 0.2 0.0 0.3 0.1 2.0 0.5 1.5 0.0 0.3 0.5 1.2 5.3 0.0 0.0 0.6 0.2 0.3 0.0 0.8 1.7 2.5 0.2 0.0 0.6 0.8 0.0 0.3 0.1 0.1 0.8 0.2 0.0 1.1 1.1 0.5 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 10.1 8.5 6.4 11.1 10.3 10.2 7.3 7.0 4.8 5.5 7.3 9.7 0.3 0.0 0.0 19.6 0.0 0.6 0.3 0.2 1.2 2.6 0.3 0.9 0.4 0.0 0.1 0.0 0.0 1.0 0.2 0.2 0.0 0.1 1.3 0.2 1.1 0.5 0.0 0.0 11.3 0.0 0.2 1.3 0.0 0.4 0.0 1.0 0.7 0.0 0.1 0.0 12.7 0.0 0.0 0.0 0.8 3.9 2.1 0.2 0.0 2.8 0.1 2.5 0.0 92.0 43.7 0.2 0.1 17.3 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.6 0.2 0.0 0.1 0.4 0.3 0.2 4.5 0.1 0.3 NLK ENSG00000087095 "Nemo like kinase" Q9UBE8 17 28041737-28196381 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Wnt signaling pathway" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 78.6" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 154.3;Early spermatids: 261.1;Excitatory neurons: 315.5;Late spermatids: 355.3;Oligodendrocytes: 366.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 45 "basophil: 29.9" "Lineage enriched" "Detected in single" 45 "granulocytes: 29.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018192, HPA056511" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Nucleoli, Cell Junctions" "HPA018192: AB_1854525, HPA056511: AB_2683160" "unprognostic (7.19e-2)" "unprognostic (1.98e-1)" "unprognostic (5.54e-2)" "unprognostic (5.64e-3)" "unprognostic (2.11e-1)" "unprognostic (1.29e-1)" "unprognostic (1.67e-2)" "unprognostic (2.59e-3)" "unprognostic (2.72e-2)" "unprognostic (4.23e-3)" "unprognostic (1.07e-2)" "unprognostic (1.09e-2)" "unprognostic (5.29e-2)" "unprognostic (1.66e-1)" "unprognostic (3.92e-1)" "unprognostic (5.27e-2)" "unprognostic (6.57e-2)" 8.2 36.6 16.7 8.6 27.6 9.9 9.4 5.7 41.9 7.9 1.0 9.0 10.3 7.0 11.2 5.5 6.4 8.7 11.5 28.5 9.2 16.6 11.1 9.1 16.4 11.9 10.4 5.0 14.3 28.2 11.1 12.2 8.4 8.2 9.2 78.6 7.4 10.8 6.6 5.9 10.2 5.9 6.5 12.2 8.9 22.0 12.2 13.2 16.8 6.7 15.4 10.1 4.5 30.1 9.5 11.6 28.4 9.7 6.1 7.6 12.1 9.6 10.9 16.9 13.1 59.4 9.1 13.6 13.8 8.4 20.2 8.6 19.6 18.7 19.3 29.7 12.2 52.2 11.2 9.9 10.3 11.6 51.0 9.6 11.9 10.4 12.5 16.0 20.4 36.3 20.1 15.9 16.4 11.6 28.8 13.4 10.4 20.1 5.5 23.8 17.2 10.0 32.0 12.2 19.6 7.2 14.4 14.4 62.4 32.2 22.0 18.2 19.2 11.7 14.1 9.0 19.5 17.6 17.9 13.1 11.6 12.6 13.0 29.9 0.3 0.3 0.5 0.4 0.2 0.6 0.5 0.6 0.3 0.3 0.3 0.6 0.2 0.2 0.5 0.5 0.5 0.3 16.7 27.6 5.7 41.9 28.5 9.2 11.9 10.4 8.4 6.5 12.2 30.1 17.8 22.4 6.0 57.8 7.8 5.4 3.8 3.0 5.7 94.4 8.7 5.0 27.4 5.7 5.3 33.1 154.3 3.7 4.3 11.4 1.9 3.9 261.1 8.9 5.8 15.0 28.2 11.8 315.5 6.4 3.5 4.8 5.1 11.9 24.1 17.6 9.3 9.4 8.8 37.0 98.2 10.0 2.0 16.9 6.0 355.3 5.6 11.3 16.0 103.0 7.9 11.2 6.2 104.5 366.6 5.7 8.1 2.6 6.4 5.4 5.1 8.4 9.5 89.9 13.1 5.0 6.9 37.1 11.8 4.1 4.8 6.4 5.5 6.7 10.3 6.6 NLRX1 "CLR11.3, NOD9" ENSG00000160703 "NLR family member X1" Q86UT6 11 119166568-119184016 "Predicted intracellular proteins" "Host-virus interaction, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 43.2" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 15.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 15.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA061516 Supported Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 6: T47d - Mammary gland" "Cluster 54: Cardiomyocytes - Muscle contraction" Mitochondria "Plasma membrane, Cell Junctions" "HPA061516: AB_2684548" "unprognostic (7.58e-2)" "unprognostic (3.71e-1)" "unprognostic (6.36e-2)" "prognostic favorable (2.47e-5)" "unprognostic (5.60e-3)" "unprognostic (2.59e-2)" "unprognostic (2.06e-1)" "unprognostic (2.43e-2)" "unprognostic (8.80e-2)" "unprognostic (1.17e-1)" "unprognostic (3.49e-1)" "unprognostic (3.29e-1)" "prognostic favorable (2.59e-6)" "unprognostic (3.06e-2)" "unprognostic (1.70e-1)" "unprognostic (2.83e-2)" "unprognostic (4.22e-2)" 8.1 10.7 4.9 4.7 5.0 6.5 7.0 4.7 5.5 10.5 6.4 10.8 4.8 10.1 3.4 43.2 9.8 5.2 17.0 4.7 4.6 8.8 9.1 5.5 5.0 5.3 5.1 4.0 9.6 6.0 4.8 4.2 5.4 8.3 3.4 2.7 10.3 6.8 24.1 21.5 6.4 5.8 5.1 8.1 7.3 3.5 5.1 4.7 7.9 13.7 10.5 9.6 16.5 5.2 5.3 15.6 1.6 12.2 5.1 5.9 2.4 7.0 8.0 3.4 5.9 0.9 13.0 9.5 21.0 8.9 5.1 13.1 4.7 4.0 1.1 12.5 5.0 12.6 5.5 8.6 7.7 4.4 7.0 6.6 16.4 4.5 8.7 6.9 7.0 12.5 0.1 6.2 3.6 14.2 7.5 10.7 7.5 6.9 8.6 14.6 2.1 3.1 8.2 6.8 2.3 7.9 10.4 5.5 4.5 2.4 17.7 13.0 8.2 6.8 6.0 6.1 3.6 2.2 2.6 3.3 1.0 13.4 4.9 2.8 3.5 15.4 0.8 1.5 1.0 0.5 0.8 1.2 2.1 0.4 0.9 1.0 8.1 1.4 1.4 0.9 1.4 2.3 4.9 5.0 4.7 5.5 4.7 4.6 5.3 5.1 5.4 5.1 5.1 5.2 3.0 0.0 7.9 5.9 3.2 2.5 1.7 4.5 2.8 1.3 4.1 4.2 12.8 2.8 4.2 7.3 2.1 3.6 1.4 7.3 1.9 7.1 2.0 8.7 2.8 3.8 2.4 3.8 5.9 3.8 2.2 3.5 8.2 4.1 0.0 5.7 5.3 10.2 6.5 0.0 4.0 3.7 2.0 6.0 1.8 4.7 1.2 4.0 1.8 2.8 6.2 6.1 5.2 5.5 2.8 5.5 7.6 1.2 1.8 1.6 3.9 5.3 7.2 3.2 0.0 2.9 2.7 1.9 2.0 10.8 4.7 0.5 2.8 2.1 5.5 1.2 NMB "MGC17211, MGC2277, MGC3936" ENSG00000197696 "Neuromedin B" P08949 15 84655129-84658563 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 68.3;brain: 58.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 319.5;Club cells: 164.2;Ductal cells: 123.9" "Cancer enhanced" "Detected in all" "glioma: 93.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 90.1" "Region enriched" "Detected in all" 16 "olfactory bulb: 168.0" "Group enriched" "Detected in all" 5 "olfactory bulb: 43.3;pons: 14.1" CAB019302 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted to blood" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Vesicles" "Plasma membrane" "CAB019302: " "unprognostic (2.44e-2)" "unprognostic (1.10e-1)" "unprognostic (2.34e-3)" "unprognostic (3.79e-1)" "prognostic favorable (3.43e-4)" "unprognostic (3.81e-1)" "unprognostic (6.45e-2)" "unprognostic (1.45e-2)" "unprognostic (2.17e-1)" "unprognostic (4.36e-1)" "unprognostic (7.24e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.25e-4)" "unprognostic (7.92e-3)" "unprognostic (1.45e-1)" "unprognostic (1.71e-2)" "unprognostic (1.00e-1)" 68.3 24.0 19.9 4.1 17.9 6.0 30.7 18.2 23.5 8.3 16.3 5.3 3.1 7.5 4.9 6.9 8.6 4.8 5.4 21.4 58.9 10.7 3.1 6.2 5.7 29.3 22.7 7.1 8.4 4.5 9.8 1.9 26.2 5.0 2.9 3.0 7.4 2.5 2.5 4.9 4.1 4.7 22.4 4.8 5.5 11.9 21.4 4.5 17.7 3.1 3.0 8.5 6.5 44.7 90.1 35.3 6.1 1.3 17.1 7.7 0.8 4.7 10.5 12.5 16.6 12.9 23.5 3.4 12.9 14.7 0.1 15.0 34.0 7.0 7.4 30.3 36.7 12.4 13.2 59.7 4.4 8.2 13.6 7.6 2.8 18.2 7.2 7.6 17.9 23.3 0.2 1.4 6.9 55.2 8.8 30.0 22.9 18.0 8.9 25.7 0.1 38.7 11.5 7.3 3.1 34.6 8.2 5.1 40.5 6.0 5.9 33.8 4.0 2.4 10.3 10.3 7.9 0.7 9.9 8.2 26.3 52.9 14.1 0.0 1.0 7.8 7.9 0.7 2.9 5.9 5.9 7.7 4.5 11.3 5.8 4.1 1.6 1.8 0.5 13.4 7.6 3.4 19.9 17.9 18.2 23.5 21.4 58.9 29.3 22.7 26.2 22.4 21.4 44.7 39.0 3.2 2.7 5.5 13.6 15.6 29.5 319.5 21.6 1.9 30.7 37.6 3.5 20.0 164.2 31.3 0.0 2.4 25.3 5.3 13.7 123.9 33.7 21.3 7.3 19.6 18.6 7.4 0.6 58.2 14.1 19.7 11.2 15.6 5.7 12.0 7.5 3.7 32.3 5.0 1.2 6.5 18.3 8.8 86.4 29.0 4.4 26.0 33.8 1.9 18.5 6.5 25.7 2.0 1.0 45.2 5.1 3.8 32.5 39.3 0.8 32.0 57.8 4.1 13.1 22.5 28.6 24.0 21.6 29.5 12.8 3.1 19.7 8.2 9.1 60.6 NMBR "BB1, BB1R" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142088799 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;testis: 1.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Early spermatids: 7.0;Excitatory neurons: 2.3;Inhibitory neurons: 4.5;Late spermatids: 2.1;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 2.5;Spermatocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.6 0.2 1.3 1.0 1.1 1.5 1.1 0.5 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NME1 "NDPKA, NM23, NM23-H1" ENSG00000239672 "NME/NM23 nucleoside diphosphate kinase 1" P15531 17 51153559-51162428 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Endocytosis, Neurogenesis, Nucleotide metabolism" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008467, CAB040571, HPA041113" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 21000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB040571: , HPA008467: AB_1079492, HPA041113: AB_2677305" "unprognostic (2.24e-1)" "unprognostic (2.01e-1)" "unprognostic (3.48e-3)" "unprognostic (5.96e-2)" "unprognostic (9.71e-2)" "unprognostic (2.33e-3)" "prognostic unfavorable (2.60e-5)" "unprognostic (4.54e-2)" "unprognostic (3.35e-1)" "unprognostic (2.33e-3)" "unprognostic (2.90e-2)" "unprognostic (1.01e-1)" "prognostic unfavorable (2.07e-9)" "unprognostic (9.01e-2)" "unprognostic (1.51e-1)" "unprognostic (1.83e-1)" "unprognostic (9.46e-2)" 63.6 84.4 79.3 74.7 81.6 77.0 63.1 78.7 102.2 38.2 79.0 60.1 38.8 49.7 46.8 91.0 48.6 20.8 37.7 88.0 92.0 65.4 83.2 41.3 73.9 83.9 78.4 33.6 67.8 52.8 47.4 39.2 82.4 38.7 77.6 218.4 50.7 30.4 35.6 57.5 33.1 66.3 76.5 48.5 41.8 25.3 81.0 61.1 41.3 20.9 95.8 72.2 48.9 80.1 483.6 833.1 285.9 444.8 118.6 183.7 479.7 355.3 227.3 652.2 489.7 656.9 288.1 754.2 372.4 304.1 272.4 252.1 542.5 553.3 553.4 398.4 729.3 504.9 605.8 975.9 237.1 575.8 243.8 177.8 341.7 493.1 458.6 120.6 404.6 247.8 739.0 270.0 392.8 720.4 715.2 647.1 390.7 957.5 739.3 446.9 587.6 751.3 511.5 320.2 418.6 461.1 188.1 521.0 385.3 246.2 554.0 419.6 279.5 476.9 452.2 307.0 774.4 374.0 840.9 956.3 286.2 480.4 385.8 1.1 55.0 2.1 47.2 77.1 69.3 96.4 50.3 53.8 134.0 67.6 54.3 60.4 1.7 69.6 48.6 84.8 49.1 68.4 79.3 81.6 78.7 102.2 88.0 92.0 83.9 78.4 82.4 76.5 81.0 80.1 53.1 32.1 30.5 0.0 71.3 132.4 97.5 198.8 88.8 283.3 98.8 118.1 34.2 65.8 92.3 71.7 285.7 180.0 25.4 54.2 150.6 211.3 34.2 40.2 107.2 85.1 89.7 81.8 0.0 201.5 269.7 85.0 64.2 37.2 45.7 113.5 27.8 123.3 207.1 40.4 0.0 107.4 101.7 25.7 88.9 93.7 61.2 48.9 129.9 0.0 47.2 105.6 27.8 0.0 0.0 194.0 50.5 58.6 113.8 170.6 12.2 195.2 42.0 323.7 13.1 83.0 182.9 22.7 98.8 139.4 133.1 88.5 38.0 215.5 157.7 98.2 NME2 "NDPKB, NM23-H2" ENSG00000243678 "NME/NM23 nucleoside diphosphate kinase 2" P22392 17 51165435-51171744 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Nucleotide metabolism, Transcription, Transcription regulation" "Activator, DNA-binding, Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 918.0;Gastric mucus-secreting cells: 438.3;Plasma cells: 778.5;Squamous epithelial cells: 1490.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB036213, CAB036214, CAB036215, HPA041113" Approved Supported "Plasma membrane,Midbody ring,Cytosol" Yes NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane, Midbody ring" "CAB036213: , CAB036214: , CAB036215: , HPA041113: AB_2677305" "unprognostic (7.21e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.85e-2)" "unprognostic (1.15e-2)" "unprognostic (8.86e-2)" "unprognostic (1.42e-2)" "prognostic unfavorable (7.09e-4)" "unprognostic (6.62e-3)" "unprognostic (5.68e-2)" "unprognostic (2.31e-1)" "unprognostic (1.38e-1)" "unprognostic (6.41e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (2.82e-1)" "unprognostic (9.09e-2)" "unprognostic (8.87e-2)" "unprognostic (3.19e-2)" 503.5 428.3 308.0 259.5 319.0 329.4 489.1 328.0 379.9 439.2 431.1 409.2 335.1 383.4 236.1 610.6 350.6 187.0 403.9 313.7 338.6 478.1 428.4 339.6 288.9 326.6 320.7 500.1 632.0 201.8 234.9 204.8 321.3 367.7 330.4 63.3 432.4 247.5 545.7 540.3 307.6 286.2 326.8 336.0 403.5 77.8 333.3 190.0 305.3 353.7 289.1 463.5 464.2 333.4 1638.6 2233.9 466.1 913.7 969.3 1399.2 1449.2 1091.7 954.0 1404.8 1053.5 1789.7 792.3 1314.3 1662.9 913.0 706.6 956.2 947.3 1273.3 1035.7 1604.8 3283.2 1120.3 1345.8 2513.4 1116.1 1736.0 760.5 1324.1 1420.0 901.9 1466.4 914.6 860.9 856.5 1541.7 773.7 956.1 2741.9 931.3 2144.8 831.4 2974.6 3364.2 875.9 1731.8 2157.2 1417.9 1800.2 1160.6 641.9 674.1 1472.7 1583.0 806.1 1201.7 1268.5 1013.5 1462.8 1158.2 1135.2 1774.8 1520.9 2176.6 1558.1 815.1 919.1 819.2 66.8 243.4 14.0 166.7 325.5 235.6 338.9 211.9 183.3 439.5 259.2 153.5 170.0 13.8 251.6 282.5 478.1 211.2 298.2 308.0 319.0 328.0 379.9 313.7 338.6 326.6 320.7 321.3 326.8 333.3 333.4 9.7 28.9 67.2 0.0 146.8 14.5 8.3 10.8 918.0 0.9 41.6 35.9 0.0 22.8 85.7 5.5 0.0 10.0 10.1 7.1 37.2 47.4 0.6 16.4 34.3 60.9 14.6 298.2 0.0 34.5 27.8 99.0 438.3 21.3 42.9 6.8 22.9 37.6 16.4 0.0 0.0 19.3 8.2 34.8 17.4 2.1 25.7 136.7 10.6 0.0 55.5 0.4 2.1 0.0 0.0 40.7 15.6 12.8 778.5 7.6 11.7 33.8 63.6 0.8 6.6 10.2 43.3 0.6 5.6 1490.1 14.9 8.8 87.0 6.8 25.0 11.0 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 44957992-45109016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 344.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA 94000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.3 31.8 36.2 22.3 37.7 19.5 25.8 30.3 43.4 24.7 27.9 27.8 23.6 26.4 15.7 28.8 27.7 20.3 28.3 38.8 36.4 27.3 39.5 26.5 33.6 35.4 33.7 26.3 22.2 37.8 23.3 36.6 35.0 24.5 29.2 25.7 32.1 27.6 44.6 23.9 26.4 32.9 33.9 28.4 24.5 24.9 37.2 35.2 30.7 47.6 39.5 33.0 23.5 34.9 51.5 88.8 53.7 42.3 82.9 75.0 60.6 41.4 87.6 115.9 101.0 83.9 57.0 54.0 86.2 80.4 78.4 51.5 94.5 92.3 132.9 117.9 73.3 49.0 60.7 84.4 53.7 71.0 62.6 66.4 64.1 79.1 69.2 64.1 87.1 60.9 81.8 38.1 63.1 49.2 76.2 31.7 42.4 151.5 87.8 57.5 67.2 52.2 73.6 78.8 39.2 32.9 33.0 30.2 38.0 112.8 73.1 46.0 50.1 69.9 49.5 55.8 68.1 41.4 61.0 69.9 64.5 44.5 56.4 34.9 49.4 20.0 23.8 33.3 19.9 42.3 19.9 20.1 26.2 31.0 23.7 18.8 26.5 21.1 27.6 115.5 25.7 11.8 36.2 37.7 30.3 43.4 38.8 36.4 35.4 33.7 35.0 33.9 37.2 34.9 50.1 38.5 29.5 49.3 53.8 13.9 15.4 48.8 24.5 97.8 74.1 57.1 46.5 97.2 33.6 69.9 116.7 73.7 87.5 48.7 78.2 69.4 31.1 51.5 63.1 46.4 50.9 72.0 30.3 71.2 61.9 39.6 21.9 62.3 22.8 28.1 85.3 344.4 47.6 129.5 30.7 43.0 28.5 86.5 15.9 12.2 55.0 34.6 10.6 18.7 97.9 41.5 59.8 20.1 19.3 67.9 52.0 51.1 31.0 15.3 84.1 108.1 24.0 123.5 59.2 16.1 46.3 67.6 35.5 20.5 14.1 81.8 40.1 25.4 68.6 18.6 NMT2 ENSG00000152465 "N-myristoyltransferase 2" O60551 10 15102584-15168693 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 93.6;Hepatocytes: 141.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 14.5;eosinophil: 13.6;gdT-cell: 11.0;MAIT T-cell: 19.8;memory CD4 T-cell: 17.5;memory CD8 T-cell: 12.9;naive CD4 T-cell: 21.8;naive CD8 T-cell: 14.5;NK-cell: 20.8;T-reg: 29.5" "Group enriched" "Detected in many" 8 "granulocytes: 14.5;NK-cells: 20.8;T-cells: 29.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 102.6;TIME: 147.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001303 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Plasma membrane, Cytosol" "HPA001303: AB_1079494" "unprognostic (1.08e-1)" "unprognostic (7.65e-2)" "unprognostic (8.78e-2)" "unprognostic (1.15e-3)" "unprognostic (6.97e-2)" "unprognostic (2.24e-1)" "unprognostic (7.11e-2)" "unprognostic (5.13e-2)" "unprognostic (3.20e-1)" "unprognostic (4.01e-3)" "unprognostic (3.31e-1)" "unprognostic (2.00e-1)" "unprognostic (7.06e-2)" "unprognostic (3.79e-3)" "unprognostic (2.00e-1)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" 25.9 4.4 7.3 6.1 8.7 3.7 17.5 12.2 10.0 9.8 4.0 8.8 6.6 12.7 3.5 7.0 8.3 7.0 8.7 7.0 4.9 9.4 16.8 6.3 8.9 5.0 7.6 15.4 5.6 16.5 5.5 4.4 5.1 9.0 9.2 7.0 5.2 7.7 8.3 10.1 10.9 10.5 4.3 9.4 7.9 13.4 9.1 27.0 5.9 8.5 8.0 8.6 7.9 7.3 8.8 11.3 12.7 9.3 33.7 35.9 2.3 18.8 15.3 17.0 23.0 10.9 38.7 0.4 12.7 102.6 46.6 10.6 11.4 10.7 28.3 11.7 13.9 23.4 5.4 15.2 22.4 1.7 84.0 31.9 10.8 23.8 7.2 62.2 65.8 16.3 11.2 1.5 63.7 10.9 18.3 4.4 9.3 10.0 10.5 13.6 18.5 1.8 12.6 1.8 3.9 14.4 22.8 3.7 6.3 10.5 11.7 7.3 147.1 16.7 24.4 75.0 13.7 13.0 14.3 1.0 20.7 6.3 12.4 14.5 0.5 13.6 11.0 0.7 19.8 2.2 17.5 12.9 0.5 2.5 21.8 14.5 1.9 20.8 0.8 0.5 29.5 6.5 7.3 8.7 12.2 10.0 7.0 4.9 5.0 7.6 5.1 4.3 9.1 7.3 52.5 9.6 8.8 25.1 16.0 16.6 23.4 8.3 7.4 20.6 14.7 13.1 13.5 57.2 10.9 27.6 4.2 1.3 16.9 32.8 9.8 33.9 6.6 4.7 20.5 21.7 18.0 15.1 39.6 19.5 3.0 16.3 9.2 10.3 93.6 13.2 25.4 141.9 2.8 20.2 30.1 11.4 4.1 7.9 7.1 14.5 21.8 5.8 12.4 17.8 10.1 12.9 40.2 12.5 15.3 27.1 15.9 20.7 10.0 17.9 38.4 63.2 5.3 17.2 0.0 13.4 21.0 8.1 46.8 6.8 14.8 2.6 33.9 11.0 18.1 16.7 NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 6.2" "Group enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 5.1;Oligodendrocytes: 8.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 9.6" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" 0.0 0.1 1.0 0.0 3.5 0.0 0.0 1.4 1.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.7 3.0 0.4 0.0 0.3 0.0 4.5 2.1 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.8 0.0 1.0 1.5 3.0 0.6 0.5 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.5 1.4 1.8 0.7 3.0 4.5 2.1 4.1 3.8 3.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 23.0;skeletal muscle: 36.9;tongue: 57.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.0;Hepatic stellate cells: 18.2;Inhibitory neurons: 32.1;Oligodendrocyte precursor cells: 48.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4.6;RH-30: 9.4;RPTEC TERT1: 5.8;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "CAB002167: AB_564073, HPA058312: AB_2683676, HPA069509: " "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (6.64e-3)" "unprognostic (4.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-4)" "unprognostic (1.87e-1)" 0.1 0.1 12.7 0.4 12.4 0.2 0.1 5.7 7.0 0.3 0.0 2.2 0.1 0.1 0.2 0.8 0.3 0.0 0.0 4.0 16.2 1.3 0.0 0.8 0.1 12.1 11.0 0.0 1.4 0.0 0.9 0.0 12.2 0.9 0.4 0.3 3.4 0.1 36.9 1.9 0.4 0.3 2.3 0.0 0.2 0.5 23.0 0.0 0.1 57.2 0.1 0.0 0.7 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 9.4 0.0 5.8 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 12.7 12.4 5.7 7.0 4.0 16.2 12.1 11.0 12.2 2.3 23.0 3.3 0.0 0.0 0.0 1.3 0.0 3.8 10.0 2.4 4.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 3.0 5.1 0.4 3.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 8.4 0.0 0.0 18.2 0.0 0.0 0.0 32.1 0.2 0.0 0.3 0.7 0.6 0.3 0.2 1.8 1.9 0.0 0.0 0.0 48.2 5.7 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.1 1.8 0.1 0.6 0.0 0.2 0.0 0.0 1.0 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NOXRED1 "C14orf148, FLJ32809" ENSG00000165555 "NADP dependent oxidoreductase domain containing 1" Q6NXP6 14 77394021-77423517 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.9;testis: 6.9" "Group enriched" "Detected in some" 25 "Early spermatids: 137.8;Late spermatids: 125.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055658, HPA060408" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Spermatids - Unknown function" Vesicles "Plasma membrane" "HPA055658: AB_2682878, HPA060408: " "unprognostic (1.92e-2)" "unprognostic (4.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (2.49e-2)" "unprognostic (9.87e-2)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (2.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.24e-2)" "unprognostic (1.29e-2)" "unprognostic (2.60e-1)" "unprognostic (5.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.07e-3)" 0.2 0.6 0.5 0.1 0.6 0.2 0.5 0.2 0.5 0.2 1.7 0.5 0.5 0.5 0.5 0.3 0.5 0.6 0.1 0.5 0.6 0.5 0.3 0.3 0.6 0.8 1.0 0.3 0.4 0.2 0.7 0.3 0.7 0.3 0.5 5.9 0.2 0.4 0.1 1.1 0.3 0.4 0.9 0.5 0.2 6.9 0.5 0.5 0.9 0.0 0.4 0.2 0.2 0.7 0.3 0.7 0.3 0.4 0.1 0.7 0.5 0.3 0.5 0.3 0.2 0.4 0.3 0.7 0.1 0.6 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.7 0.2 0.1 0.6 0.4 0.9 0.3 0.5 0.4 0.2 0.8 0.1 0.5 0.1 0.8 0.2 0.2 0.0 0.2 0.6 0.2 0.1 0.0 0.3 0.1 0.7 0.5 0.4 0.1 0.1 0.7 0.7 0.4 0.9 0.2 0.2 0.4 0.1 0.7 0.7 0.4 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.5 0.5 0.6 0.8 1.0 0.7 0.9 0.5 0.7 0.2 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.1 0.0 0.1 0.0 4.2 0.0 0.0 0.3 0.0 0.0 137.8 0.6 0.1 0.2 1.8 0.0 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.0 3.0 0.0 0.0 0.3 0.2 125.8 0.9 0.3 0.0 0.0 0.0 0.4 0.0 3.0 4.4 0.1 0.0 1.2 0.1 0.1 0.3 0.1 0.2 1.5 0.0 0.0 0.1 4.1 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 NPAP1 C15orf2 ENSG00000185823 "Nuclear pore associated protein 1" Q9NZP6 15 24675775-24683393 "Predicted intracellular proteins, Transporters" "Differentiation, Spermatogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.8;testis: 2.9" "Cell type enriched" "Detected in some" 5 "Granulosa cells: 125.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018828, HPA019562" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Vesicles, Plasma membrane" "HPA018828: AB_2669941, HPA019562: AB_2670190" "unprognostic (4.40e-2)" "unprognostic (1.85e-2)" "unprognostic (6.98e-3)" "unprognostic (7.45e-2)" "unprognostic (9.90e-2)" "unprognostic (1.08e-2)" "unprognostic (5.11e-3)" 0.0 0.0 0.9 0.0 1.8 0.4 0.1 0.1 1.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.5 1.7 0.9 0.0 0.0 0.1 0.9 0.7 0.5 0.4 0.0 0.5 0.0 0.5 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.5 0.1 0.1 2.9 1.5 0.0 0.5 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.9 1.8 0.1 1.1 0.5 1.7 0.9 0.7 0.5 0.5 1.5 1.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.1 0.2 0.7 0.1 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.1 0.0 125.9 0.0 0.0 0.1 0.0 3.5 0.0 0.0 0.0 0.0 0.8 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 1.3 24.1 12.7 0.0 0.0 0.0 0.0 0.5 0.0 0.2 NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031804-72148067 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.2;seminal vesicle: 3.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 22.1;Cytotrophoblasts: 6.6;Excitatory neurons: 14.5;Extravillous trophoblasts: 12.3;Muller glia cells: 4.9;Syncytiotrophoblasts: 9.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "GAMG: 28.1;NTERA-2: 9.2;RPTEC TERT1: 11.9;SH-SY5Y: 14.0;U-2 OS: 13.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" 0.1 0.0 1.0 0.2 0.9 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.9 0.0 0.2 0.1 0.0 0.9 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.2 0.7 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.2 7.2 0.3 0.2 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 14.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.6 0.9 1.1 0.5 0.0 0.3 0.0 0.2 0.5 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 22.1 0.0 0.5 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.0 14.5 0.2 12.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 3.5 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.0 0.0 9.7 0.0 0.0 0.0 0.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NPNT "EGFL6L, POEM" ENSG00000168743 Nephronectin Q6UXI9 4 105894775-106004027 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 137.0;thyroid gland: 234.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 185.9;Alveolar cells type 2: 103.7;Club cells: 56.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 104.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 30.9;CAPAN-2: 19.1;HeLa: 32.3;Hep G2: 27.1;MCF7: 24.3;RPTEC TERT1: 37.7;T-47d: 51.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003711, HPA050203" Supported Approved "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to extracellular matrix" NA NA 120000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Cell Junctions, Cytosol" "HPA003711: AB_1854591, HPA050203: AB_2681050" "unprognostic (1.24e-1)" "unprognostic (7.93e-2)" "unprognostic (1.59e-1)" "unprognostic (2.43e-2)" "unprognostic (3.92e-1)" "unprognostic (2.49e-1)" "unprognostic (1.87e-1)" "unprognostic (7.85e-3)" "unprognostic (4.78e-4)" "unprognostic (1.19e-2)" "unprognostic (1.57e-1)" "unprognostic (1.68e-1)" "prognostic favorable (8.28e-8)" "unprognostic (4.81e-2)" "unprognostic (1.21e-1)" "unprognostic (1.77e-1)" "unprognostic (2.31e-2)" 22.8 6.3 9.7 5.6 7.9 0.2 27.0 4.7 8.0 32.4 5.7 24.5 56.1 20.9 22.2 10.9 22.4 30.5 5.2 7.5 14.6 105.0 4.0 137.0 4.5 6.1 31.8 10.9 40.1 1.0 47.4 3.4 9.2 82.9 25.2 2.4 8.9 18.7 4.9 8.2 74.1 14.1 4.4 14.8 14.9 3.1 10.5 14.2 234.5 11.5 5.4 9.7 22.1 6.6 0.0 0.2 0.3 0.6 0.0 0.0 30.9 0.2 0.1 0.0 0.0 14.9 19.1 0.2 0.8 0.2 0.0 1.7 7.4 0.0 0.0 0.0 8.4 0.8 32.3 27.1 0.1 0.0 0.2 3.2 2.4 0.0 0.0 0.3 0.0 0.4 0.1 0.4 0.0 24.3 0.4 1.5 0.3 0.1 12.0 0.0 0.1 0.3 37.7 1.6 1.7 0.6 1.8 14.1 0.0 4.1 51.2 1.3 0.0 0.6 0.4 0.5 1.1 0.3 1.1 0.0 0.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 7.9 4.7 8.0 7.5 14.6 6.1 31.8 9.2 4.4 10.5 6.6 5.2 185.9 103.7 15.3 0.0 1.9 5.2 13.1 1.8 1.1 22.2 7.0 2.5 27.1 56.4 33.1 0.0 2.4 0.7 5.9 1.9 24.7 11.0 1.0 1.5 18.4 15.6 0.0 1.0 2.5 0.2 8.3 1.1 1.9 0.0 3.3 2.9 0.3 0.3 0.0 10.0 10.6 4.1 0.0 1.5 15.4 2.5 0.6 5.4 14.0 0.0 0.0 0.0 2.0 0.3 7.5 3.4 0.0 0.0 28.4 19.6 4.3 6.4 0.2 0.0 1.9 26.4 2.4 2.0 3.6 1.1 1.5 0.3 1.5 11.0 5.7 NPR1 "ANPa, ANPRA, GUCY2A, NPRA" ENSG00000169418 "Natriuretic peptide receptor 1" P16066 1 153678688-153693992 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "cGMP biosynthesis" "Lyase, Receptor, Vasoactive" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 67.1" "Group enriched" "Detected in many" 6 "Adipocytes: 99.6;Endothelial cells: 52.5;Hepatic stellate cells: 132.8" "Group enriched" "Detected in all" 4 "ovarian cancer: 39.2;renal cancer: 12.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "ASC diff: 158.5" "Region enriched" "Detected in all" 5 "olfactory bulb: 18.7" "Low region specificity" "Detected in many" HPA031087 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoli "Nucleoplasm, Plasma membrane" "HPA031087: AB_10601975" "unprognostic (2.54e-1)" "unprognostic (3.03e-3)" "unprognostic (6.31e-2)" "prognostic unfavorable (3.97e-4)" "unprognostic (1.55e-1)" "unprognostic (6.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.03e-1)" "unprognostic (2.46e-1)" "unprognostic (3.27e-2)" "prognostic favorable (2.49e-4)" "unprognostic (1.27e-1)" "unprognostic (6.69e-2)" "unprognostic (1.16e-2)" "unprognostic (1.09e-1)" "unprognostic (4.06e-1)" "unprognostic (1.74e-2)" 67.1 8.7 1.7 3.4 1.5 0.0 44.3 1.4 1.4 8.8 1.5 10.1 1.5 31.0 5.5 4.3 36.4 5.9 15.8 1.3 1.4 28.8 4.3 24.2 2.3 1.5 1.5 27.7 3.9 8.4 3.8 17.7 1.5 4.4 2.0 0.1 3.7 12.1 7.2 6.6 9.3 9.7 1.8 2.2 8.8 1.3 2.4 1.9 14.0 11.1 1.3 12.8 9.7 1.4 0.0 1.3 0.1 0.0 158.5 0.6 0.1 0.0 0.0 0.1 0.1 0.1 0.6 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 28.0 0.0 19.0 0.0 0.0 0.3 0.0 0.3 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.0 0.0 15.9 0.0 0.0 2.1 0.0 0.1 0.0 1.9 0.0 5.7 1.0 0.1 0.0 0.2 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.5 1.4 1.4 1.3 1.4 1.5 1.5 1.5 1.8 2.4 1.4 99.6 0.0 6.9 0.0 0.2 1.5 0.5 0.0 0.6 0.0 0.5 0.5 4.5 2.8 0.0 14.7 0.0 0.2 0.1 0.0 0.0 0.7 9.1 6.2 8.8 52.5 0.0 0.0 0.0 0.0 1.3 15.2 0.0 15.4 0.0 0.0 132.8 2.4 0.3 0.0 0.0 0.0 0.0 4.7 4.0 11.5 10.2 0.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 1.0 0.0 4.1 0.0 0.5 0.0 4.0 0.0 0.0 0.0 1.4 2.2 0.5 0.1 0.2 1.0 0.7 0.3 1.4 0.2 0.0 NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" 84.6 95.7 81.4 75.9 104.4 32.7 82.6 52.1 176.7 112.4 72.4 133.0 134.9 180.7 150.9 133.9 135.0 97.2 196.4 122.6 65.6 126.5 74.0 110.5 48.7 42.9 42.2 79.1 96.6 167.2 47.1 123.1 39.8 170.8 142.0 135.5 101.0 204.4 51.2 68.1 124.9 298.4 28.5 71.8 96.4 69.2 60.4 42.6 112.4 70.1 69.4 140.6 84.9 87.9 101.9 179.1 100.9 74.5 201.6 180.7 141.1 229.1 373.5 258.3 228.4 122.4 317.7 58.7 133.0 331.2 319.2 411.1 164.4 191.3 147.6 105.6 109.3 46.7 83.3 110.2 143.1 72.6 124.9 149.1 165.2 167.4 100.7 254.8 139.5 52.0 26.7 65.2 187.2 81.2 32.4 45.3 93.5 127.3 63.3 52.1 115.8 49.9 353.7 148.3 61.6 19.2 222.4 122.4 151.3 249.6 110.9 97.7 159.0 199.7 133.8 116.0 135.8 56.5 113.8 51.4 185.8 111.0 140.0 5.9 13.5 13.8 6.4 18.5 5.2 3.8 3.6 5.9 5.3 2.9 3.6 4.2 28.0 3.9 14.8 5.5 4.3 13.6 81.4 104.4 52.1 176.7 122.6 65.6 42.9 42.2 39.8 28.5 60.4 87.9 67.1 76.9 66.0 72.1 18.3 65.0 27.0 43.3 51.2 93.0 50.5 45.7 106.9 48.6 60.6 82.8 50.1 7.0 28.8 133.8 1.9 18.1 3.7 73.4 46.7 44.6 103.0 7.4 216.6 24.0 9.2 64.5 41.3 92.1 28.4 33.9 50.0 43.1 25.0 38.7 162.7 90.9 42.7 77.4 46.6 9.9 15.2 61.8 42.7 86.2 43.4 41.2 12.3 63.8 67.4 41.4 66.7 38.4 20.2 26.9 52.3 20.7 92.1 49.7 19.7 35.5 74.0 11.7 10.8 61.9 54.6 6.8 23.9 35.3 52.6 30.7 NPTXR ENSG00000221890 "Neuronal pentraxin receptor" O95502 22 38818452-38844028 "Plasma proteins, Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 18 "brain: 280.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 18.0;Excitatory neurons: 41.7;Inhibitory neurons: 50.4;Oligodendrocyte precursor cells: 19.1" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "hippocampal formation: 280.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 23.3;SCLC-21H: 30.8;SiHa: 23.6;U-87 MG: 87.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001079 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 420000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" Nucleoplasm "HPA001079: AB_1078414" "unprognostic (6.29e-2)" "prognostic favorable (3.93e-4)" "unprognostic (6.82e-3)" "prognostic unfavorable (2.85e-4)" "unprognostic (9.55e-2)" "unprognostic (6.93e-2)" "unprognostic (1.05e-1)" "unprognostic (1.51e-1)" "unprognostic (1.65e-2)" "unprognostic (1.71e-1)" "unprognostic (1.52e-3)" "unprognostic (1.37e-1)" "unprognostic (1.27e-1)" "unprognostic (1.49e-2)" "unprognostic (9.22e-2)" "unprognostic (8.65e-2)" "unprognostic (2.77e-2)" 2.7 5.0 91.6 1.9 75.4 0.3 2.8 0.3 145.7 8.7 0.0 9.5 1.3 10.9 3.8 3.0 7.9 2.0 15.7 280.2 17.0 1.6 1.9 1.9 1.6 4.1 15.2 8.1 5.2 7.0 6.8 0.4 0.7 8.1 1.5 5.3 4.8 7.0 0.6 1.1 3.3 7.6 3.1 2.5 5.0 1.8 58.0 0.7 2.7 2.5 1.5 7.3 4.8 46.0 1.0 6.2 0.2 1.8 12.2 1.2 0.0 4.1 0.9 7.9 2.7 6.2 1.3 0.0 7.2 1.1 23.3 0.8 1.7 0.2 2.6 0.6 2.0 0.0 0.2 9.6 1.2 0.1 0.3 3.9 0.4 7.2 0.1 11.4 0.3 0.1 7.7 0.3 0.3 9.7 0.0 0.5 7.3 3.0 2.2 1.6 0.0 15.3 2.0 17.1 30.8 2.0 23.6 0.1 0.7 1.7 9.9 2.5 0.4 14.1 8.4 0.0 0.7 2.1 0.0 0.0 87.9 18.5 7.4 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.1 91.6 75.4 0.3 145.7 280.2 17.0 4.1 15.2 0.7 3.1 58.0 46.0 4.7 0.0 0.0 9.4 0.3 1.1 2.7 0.9 0.0 6.6 3.3 1.5 18.0 4.3 3.0 3.7 2.1 0.0 2.3 0.0 0.0 7.3 1.7 1.7 3.2 4.2 1.8 0.0 41.7 3.8 0.0 1.5 0.5 3.0 0.0 1.5 5.0 0.4 0.2 0.0 50.4 0.2 6.1 0.3 0.9 0.8 1.8 0.3 1.8 1.9 0.0 4.8 6.2 19.1 10.5 2.0 0.0 2.2 0.9 3.8 0.1 0.5 2.2 3.3 0.0 2.4 2.8 0.2 1.3 0.1 1.0 0.0 1.7 0.3 0.0 3.4 NR2C1 "TR2, TR2-11" ENSG00000120798 "Nuclear receptor subfamily 2 group C member 1" P13056 12 95020229-95073628 "Nuclear receptors, Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, DNA-binding, Receptor, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035040, HPA035041, HPA067767" Supported Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 51: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Cell Junctions, Cytosol" "HPA035040: AB_2674426, HPA035041: AB_2674427, HPA067767: AB_2685898" "unprognostic (2.44e-1)" "unprognostic (8.04e-3)" "unprognostic (3.17e-2)" "unprognostic (2.51e-1)" "unprognostic (3.56e-3)" "unprognostic (3.01e-2)" "prognostic unfavorable (5.18e-5)" "unprognostic (1.30e-2)" "unprognostic (1.29e-2)" "unprognostic (1.86e-1)" "unprognostic (3.83e-2)" "unprognostic (4.56e-2)" "prognostic unfavorable (1.03e-6)" "unprognostic (2.31e-1)" "unprognostic (1.42e-1)" "unprognostic (2.16e-1)" "prognostic favorable (5.62e-5)" 8.3 10.4 4.9 5.0 5.6 9.3 7.7 14.0 9.3 9.3 8.2 8.6 5.6 10.3 9.9 5.4 10.2 4.4 10.0 5.1 5.1 6.6 10.0 8.6 5.5 4.7 4.9 9.9 8.2 6.1 7.2 5.8 5.6 6.7 6.2 15.6 5.2 7.5 14.3 6.1 7.6 7.8 4.6 9.2 6.1 11.9 5.6 5.7 11.9 5.5 5.3 8.1 7.4 6.9 11.4 13.9 23.0 10.2 5.8 10.0 30.5 10.9 7.9 10.6 9.9 12.2 6.2 13.8 3.8 7.3 6.8 11.8 10.7 8.6 8.1 6.0 23.1 16.7 11.5 15.4 11.1 11.3 7.0 10.2 7.0 7.9 9.5 13.3 11.6 16.8 12.9 5.2 12.9 8.3 12.4 26.0 14.5 9.1 24.0 11.7 15.0 8.1 12.3 13.9 11.1 8.8 17.6 7.4 8.4 11.8 12.9 7.5 10.9 8.6 8.4 10.7 6.2 7.7 13.1 13.0 2.1 13.0 4.2 0.3 2.4 2.1 3.9 2.6 5.0 2.0 3.1 3.3 3.7 2.3 4.0 2.8 1.5 2.1 2.3 3.6 2.3 2.3 4.9 5.6 14.0 9.3 5.1 5.1 4.7 4.9 5.6 4.6 5.6 6.9 18.7 35.3 15.4 28.4 14.4 8.3 14.4 7.8 15.4 44.8 7.6 7.5 18.5 8.6 5.6 11.0 18.8 15.3 19.9 10.3 3.9 11.6 25.2 14.8 23.3 15.5 7.2 15.6 55.4 9.4 12.7 17.4 16.3 18.8 10.1 28.0 13.2 12.7 9.5 25.2 73.4 11.4 12.2 11.1 9.5 6.4 43.8 10.9 14.2 34.7 10.7 14.9 12.3 26.2 51.1 18.7 9.9 30.1 13.7 9.4 5.8 8.1 19.6 49.6 6.6 17.3 14.6 67.0 25.9 12.1 7.4 7.8 15.0 18.0 13.3 20.2 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRCAM "Bravo, KIAA0343" ENSG00000091129 "Neuronal cell adhesion molecule" Q92823 7 108147623-108456717 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 37.3;brain: 38.3;epididymis: 34.4;retina: 38.0" "Group enriched" "Detected in many" 7 "Astrocytes: 612.5;Excitatory neurons: 764.5;Inhibitory neurons: 392.4;Oligodendrocyte precursor cells: 1259.2" "Cancer enriched" "Detected in all" 7 "glioma: 57.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 6 "naive CD8 T-cell: 2.0" "Lineage enriched" "Detected in single" 15 "T-cells: 2.0" "Cell line enhanced" "Detected in many" "A549: 99.6;AF22: 94.8;EFO-21: 175.4;HMC-1: 187.9;SH-SY5Y: 115.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA012606 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in brain" NA NA 110000000 "Cluster 32: T-cells - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Vesicles, Plasma membrane" "HPA012606: AB_1854636" "unprognostic (2.66e-1)" "unprognostic (2.65e-1)" "unprognostic (2.52e-3)" "unprognostic (2.18e-2)" "unprognostic (4.08e-3)" "unprognostic (1.01e-2)" "unprognostic (4.47e-3)" "unprognostic (1.66e-1)" "unprognostic (1.73e-1)" "unprognostic (4.81e-2)" "unprognostic (9.10e-3)" "unprognostic (4.33e-2)" "unprognostic (2.22e-2)" "unprognostic (9.70e-3)" "unprognostic (6.42e-2)" "unprognostic (6.51e-3)" "unprognostic (3.28e-2)" 3.1 37.3 19.8 1.8 31.9 0.3 1.5 2.4 34.6 5.0 0.0 0.8 0.7 2.1 34.4 0.7 3.6 7.3 0.4 33.1 9.4 6.2 0.4 2.3 0.8 2.3 22.7 1.5 29.4 7.3 11.4 7.8 2.0 0.8 0.7 38.0 1.9 14.2 0.2 0.8 0.6 0.7 1.5 4.8 1.8 1.7 38.3 2.8 4.1 0.4 2.7 0.5 0.4 2.6 0.1 99.6 94.8 0.0 11.4 2.2 1.8 0.7 0.4 1.0 1.7 40.7 0.0 0.0 175.4 0.7 1.5 0.4 2.2 1.6 1.0 0.1 12.7 0.0 0.7 1.0 0.2 0.9 187.9 15.5 0.0 0.2 0.6 0.2 61.7 0.2 0.2 0.8 1.5 38.2 0.4 0.3 13.1 60.1 0.0 0.0 27.8 33.3 21.4 0.1 18.6 115.9 1.3 0.0 1.9 3.3 0.2 0.1 66.2 4.2 1.0 0.1 16.4 0.2 0.5 0.9 0.7 0.1 55.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.0 0.0 0.0 0.0 0.0 0.0 0.2 19.8 31.9 2.4 34.6 33.1 9.4 2.3 22.7 2.0 1.5 38.3 2.6 0.2 0.0 0.0 612.5 0.8 0.4 0.1 0.8 1.2 66.2 1.5 0.9 0.7 7.2 0.1 5.5 102.2 3.6 0.0 0.2 3.9 1.6 37.3 10.4 2.4 1.3 0.0 0.0 764.5 12.1 0.2 2.0 3.6 25.0 23.4 4.4 1.4 0.4 0.8 13.5 392.4 0.3 0.0 0.8 0.4 8.3 0.9 0.2 3.6 51.5 0.6 45.1 0.0 1259.2 21.9 3.7 0.0 0.4 2.6 1.2 0.0 3.3 0.1 8.8 0.0 1.0 2.6 1.1 2.7 0.2 0.1 4.4 1.1 34.2 0.0 0.0 NRP2 VEGF165R2 ENSG00000118257 "Neuropilin 2" O60462 2 205681990-205798133 "Cancer-related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Differentiation, Host-virus interaction, Neurogenesis" "Developmental protein, Heparin-binding, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 78.7" "Cell type enhanced" "Detected in many" "Endothelial cells: 134.4;Hepatic stellate cells: 137.8;Hofbauer cells: 141.3;Langerhans cells: 129.8;monocytes: 224.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 123.6;HUVEC TERT2: 105.7;TIME: 106.3;U-251 MG: 217.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039980, HPA054974" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane" "Secreted in other tissues" NA NA 29000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" Nucleoplasm "HPA039980: AB_10795517, HPA054974: AB_2682657" "unprognostic (4.28e-2)" "unprognostic (1.17e-1)" "unprognostic (8.12e-3)" "unprognostic (3.38e-1)" "unprognostic (1.62e-1)" "unprognostic (1.57e-2)" "unprognostic (9.36e-2)" "unprognostic (3.70e-1)" "unprognostic (2.15e-3)" "unprognostic (2.90e-2)" "unprognostic (2.56e-3)" "unprognostic (4.17e-1)" "prognostic unfavorable (7.68e-7)" "unprognostic (2.22e-3)" "unprognostic (5.45e-2)" "unprognostic (6.41e-3)" "prognostic unfavorable (7.80e-5)" 18.8 22.2 18.0 17.8 13.8 4.6 12.6 9.3 11.7 18.8 7.0 78.7 5.3 51.8 3.7 13.3 21.1 31.1 6.3 21.7 42.5 4.9 9.6 24.3 8.2 30.4 23.9 46.8 1.9 2.5 9.6 47.0 19.6 13.0 10.5 3.6 3.3 30.9 2.3 4.8 14.9 54.8 13.2 7.5 25.9 1.4 33.9 6.1 10.8 3.4 4.5 38.3 15.9 12.4 2.5 50.4 32.2 0.2 30.1 9.6 9.3 8.5 14.8 10.0 9.5 48.0 123.6 0.0 11.9 25.3 20.5 19.2 1.5 15.9 16.8 0.1 6.8 0.5 2.4 0.4 80.7 0.0 2.1 68.5 12.2 14.4 12.3 64.5 105.7 0.2 0.2 0.1 6.8 0.2 0.0 0.0 41.5 0.1 9.2 0.2 2.0 12.0 21.7 0.0 29.0 1.0 1.1 0.3 75.4 84.9 0.1 0.8 106.3 43.1 0.4 11.3 217.0 0.0 0.2 3.2 96.9 0.3 88.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 18.0 13.8 9.3 11.7 21.7 42.5 30.4 23.9 19.6 13.2 33.9 12.4 88.7 89.8 57.5 2.0 3.8 19.4 19.5 30.8 97.9 36.5 1.3 11.3 4.5 5.7 53.2 1.8 0.0 89.7 0.1 0.6 0.0 6.4 6.3 8.8 8.1 134.4 1.2 2.7 4.1 3.8 8.7 47.0 1.5 13.2 3.8 2.7 137.8 1.8 141.3 0.0 9.4 1.1 4.1 28.0 129.8 18.9 2.8 53.7 19.6 53.4 224.8 4.8 0.0 4.0 8.1 53.2 0.0 4.9 0.2 9.1 0.0 0.6 48.1 2.7 0.0 4.6 32.2 1.4 1.4 17.8 12.6 25.7 2.4 48.1 0.4 51.5 NRSN1 "p24, VMP" ENSG00000152954 "Neurensin 1" Q8IZ57 6 24126186-24154900 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 542.9;choroid plexus: 474.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 139.1;Horizontal cells: 121.1;Inhibitory neurons: 111.9;Oligodendrocyte precursor cells: 69.9" "Cancer enriched" "Detected in single" 17 "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 11.2;SH-SY5Y: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019681, HPA061006" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA019681: , HPA061006: AB_2684413" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (8.00e-3)" "unprognostic (8.01e-3)" "unprognostic (1.70e-1)" "unprognostic (4.53e-3)" "unprognostic (7.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.40e-3)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" 0.0 4.9 276.8 0.4 315.2 0.2 0.0 108.9 281.1 0.1 474.7 1.2 0.4 0.2 0.0 0.1 0.0 0.2 0.0 138.2 466.8 0.1 0.0 0.0 0.1 263.2 332.8 0.0 1.2 0.0 23.5 0.0 468.0 0.0 0.4 22.6 0.1 0.0 0.7 0.1 0.3 0.3 194.7 0.1 0.4 0.3 459.9 0.0 0.1 0.0 0.1 0.0 0.1 542.9 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 11.2 9.2 0.0 0.0 0.2 0.1 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.3 0.5 0.2 0.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 276.8 315.2 108.9 281.1 138.2 466.8 263.2 332.8 468.0 194.7 459.9 542.9 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.1 0.0 0.0 139.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 121.1 111.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 23.7 0.0 69.9 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NSFL1C "dJ776F14.1, p47, UBX1, UBXD10, UBXN2C" ENSG00000088833 "NSFL1 cofactor" Q9UNZ2 20 1442162-1473842 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047108, HPA050628" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 1900000 "Cluster 5: Granulocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA047108: AB_2679935, HPA050628: AB_2681194" "unprognostic (7.55e-2)" "unprognostic (5.26e-2)" "unprognostic (2.51e-2)" "unprognostic (2.47e-1)" "unprognostic (5.96e-2)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.29e-4)" "unprognostic (1.10e-2)" "unprognostic (1.59e-1)" "unprognostic (4.67e-2)" "unprognostic (2.58e-1)" "unprognostic (4.97e-2)" "unprognostic (6.90e-2)" "unprognostic (5.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.44e-2)" "unprognostic (7.50e-3)" 22.8 37.7 38.3 13.5 39.5 27.8 21.5 37.0 45.9 23.2 41.6 23.0 14.9 22.5 26.8 28.5 26.1 13.5 29.1 39.7 38.6 21.4 26.3 18.0 15.2 39.0 39.0 25.7 15.5 23.9 14.1 21.1 39.8 20.9 18.4 22.6 19.3 26.4 69.0 36.6 17.6 22.9 36.4 19.8 18.0 14.8 38.6 21.0 20.0 43.3 18.6 22.4 21.6 39.7 55.6 64.4 35.9 32.0 30.5 31.4 28.7 21.0 41.8 57.7 41.3 53.9 43.1 31.6 16.6 47.8 47.2 50.4 25.9 70.3 40.8 12.3 25.1 29.8 10.3 61.4 33.8 30.7 16.4 23.5 33.3 55.3 20.3 30.8 46.8 23.4 42.5 26.5 36.2 29.1 31.4 54.7 40.7 42.5 65.4 14.7 41.1 29.8 68.6 37.1 20.5 23.4 29.6 59.8 26.7 18.8 36.5 22.0 37.8 38.7 29.4 23.9 40.2 21.9 41.8 24.7 28.9 43.0 29.3 31.4 21.3 80.3 20.0 26.6 19.7 35.0 21.2 19.5 29.7 36.0 23.4 20.7 69.1 16.7 28.1 23.1 28.2 25.5 38.3 39.5 37.0 45.9 39.7 38.6 39.0 39.0 39.8 36.4 38.6 39.7 34.6 22.4 23.2 17.3 36.1 89.2 63.5 106.3 44.3 60.2 28.6 26.0 35.4 24.3 57.8 31.3 22.9 150.7 29.7 68.2 56.7 104.7 23.0 51.0 29.6 44.3 43.6 41.0 24.0 94.5 146.0 41.1 30.5 54.9 40.5 49.1 31.1 42.2 81.1 70.7 24.8 42.5 61.1 43.7 43.6 38.8 39.1 43.8 42.7 14.0 52.9 61.7 32.0 17.6 31.2 123.4 65.7 46.3 41.8 76.0 66.4 73.8 43.2 44.5 78.9 44.2 64.7 106.1 103.2 55.1 75.7 151.6 31.6 48.9 44.0 88.5 NT5C1B "AIRP, CN-IB" ENSG00000185013 "5'-nucleotidase, cytosolic IB" Q96P26 2 18562872-18589572 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotide metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "testis: 35.5" "Group enriched" "Detected in some" 29 "Early spermatids: 159.5;Late spermatids: 300.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in some" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" "unprognostic (4.18e-2)" "unprognostic (1.20e-2)" "unprognostic (7.67e-2)" "unprognostic (1.31e-1)" "unprognostic (1.02e-1)" "unprognostic (4.97e-2)" "unprognostic (4.96e-2)" "unprognostic (4.84e-1)" "unprognostic (8.49e-2)" "unprognostic (4.42e-2)" "unprognostic (2.91e-2)" "unprognostic (2.35e-1)" "unprognostic (1.61e-1)" "unprognostic (6.96e-2)" "unprognostic (2.50e-1)" "unprognostic (1.15e-1)" "unprognostic (3.77e-1)" 0.1 0.5 0.2 0.2 0.3 0.4 0.1 0.2 0.2 0.1 2.6 0.1 0.7 0.1 0.0 1.0 0.1 0.7 0.6 0.1 0.1 0.3 0.2 0.2 0.3 0.3 0.5 0.0 0.4 0.0 0.1 0.2 0.2 0.2 0.0 0.1 0.2 0.0 0.0 1.1 0.2 0.0 0.1 0.2 0.8 35.5 0.4 0.0 0.7 0.0 0.0 0.3 0.1 0.2 1.2 0.2 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 1.2 0.5 0.1 0.0 0.7 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.2 0.4 0.1 0.0 1.0 0.0 0.1 0.2 0.2 0.6 0.1 0.2 0.3 0.0 1.1 0.8 0.4 0.9 0.1 0.5 0.1 0.2 0.2 0.6 0.5 0.3 1.0 0.1 0.3 0.2 0.7 0.9 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.4 0.4 0.1 0.3 0.8 0.7 0.0 0.2 0.0 1.2 0.1 0.1 0.2 0.3 0.2 0.2 0.1 0.1 0.3 0.5 0.2 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 159.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 300.4 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5C1B-RDH14 ENSG00000250741 "NT5C1B-RDH14 readthrough" 2 18555545-18589564 "Metabolic proteins, Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 126 "testis: 16.6" "Group enriched" "Detected in some" 97 "Early spermatids: 52.3;Late spermatids: 64.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA056683 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 34: Spermatids - Unknown function" "Nucleoli, Plasma membrane" Nucleoplasm "HPA056683: AB_2683207" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NT5E "CALJA, CD73, eN, eNT, NT5" ENSG00000135318 "5'-nucleotidase ecto" P21589 6 85449584-85495791 "CD markers, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Hydrolase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 112.6;retina: 94.4" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 58.0;Oligodendrocyte precursor cells: 61.3;Pancreatic endocrine cells: 124.8;Rod photoreceptor cells: 81.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 33.0;naive CD8 T-cell: 30.7" "Group enriched" "Detected in many" 41 "B-cells: 33.0;T-cells: 30.7" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 807.8;LHCN-M2: 934.3;TIME: 546.2;U-87 MG: 821.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017357 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 3000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA017357: AB_1846330" "unprognostic (1.92e-2)" "unprognostic (4.44e-3)" "unprognostic (1.54e-1)" "unprognostic (1.57e-3)" "unprognostic (9.33e-2)" "unprognostic (1.82e-3)" "unprognostic (1.20e-2)" "prognostic unfavorable (6.66e-4)" "unprognostic (5.45e-2)" "unprognostic (1.80e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.39e-1)" "unprognostic (3.11e-2)" "prognostic unfavorable (1.02e-4)" "unprognostic (3.49e-2)" "unprognostic (2.26e-1)" "unprognostic (2.78e-1)" 20.7 6.0 9.8 11.9 11.9 0.6 14.1 11.2 10.7 112.6 14.9 29.4 40.1 49.4 6.3 8.6 20.7 17.2 8.7 8.5 11.3 17.2 54.8 6.8 9.6 11.7 14.1 39.3 1.8 1.8 11.8 25.3 13.0 13.3 31.9 94.4 6.6 34.2 2.1 6.4 20.9 73.9 14.7 13.0 8.1 10.4 12.7 5.2 23.7 9.8 11.3 15.8 28.5 12.1 48.9 26.0 42.9 0.8 95.1 302.4 0.4 306.1 332.7 147.5 275.2 0.4 469.6 0.0 107.3 270.2 379.0 24.5 0.1 308.0 348.8 0.8 0.1 0.1 7.3 6.0 47.5 0.2 0.7 77.4 3.7 302.0 191.3 807.8 124.9 0.3 0.3 1.4 934.3 8.3 0.0 0.2 0.8 8.2 34.6 1.5 9.5 1.3 323.1 21.8 0.3 5.5 3.8 18.8 104.9 2.2 0.4 8.3 546.2 120.6 0.9 152.9 506.8 22.7 15.3 0.5 821.7 0.4 385.3 0.0 0.0 0.5 3.7 0.0 6.4 23.7 4.2 11.7 0.0 33.0 4.1 30.7 0.5 0.7 0.0 0.1 1.7 6.4 9.8 11.9 11.2 10.7 8.5 11.3 11.7 14.1 13.0 14.7 12.7 12.1 6.4 0.0 5.8 36.9 21.6 5.2 1.7 6.1 2.8 4.4 1.2 0.3 1.7 27.1 4.8 1.8 10.4 0.6 2.2 49.2 3.9 3.8 0.6 19.3 20.8 20.5 0.0 0.0 1.6 4.1 2.5 39.4 11.2 58.0 0.0 0.1 49.6 33.7 1.3 0.0 2.1 27.7 0.0 3.5 8.2 1.3 13.1 2.1 7.2 11.2 0.5 9.1 0.0 61.3 0.7 124.8 46.0 25.6 3.6 1.5 8.3 27.6 4.8 81.6 0.0 3.3 9.6 0.0 0.3 0.6 4.8 15.2 5.0 0.1 18.0 9.6 NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.7;Excitatory neurons: 122.1;Inhibitory neurons: 162.5;Oligodendrocyte precursor cells: 425.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 75.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.7;fHDF/TERT166: 25.0;RPTEC TERT1: 27.4;U-138 MG: 21.8;U-251 MG: 16.9;U-87 MG: 24.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "hippocampal formation: 19.7;midbrain: 61.3;pons: 56.0;thalamus: 76.4" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" 3.1 4.4 17.2 0.2 3.8 0.0 0.2 6.3 6.7 3.2 0.0 2.2 0.0 0.6 0.0 0.1 0.4 0.6 0.1 7.8 15.2 8.8 0.0 3.8 0.4 5.8 28.3 0.4 0.1 0.1 2.5 1.1 4.6 3.4 0.4 10.3 0.2 4.7 0.0 1.3 0.4 0.1 3.2 0.3 0.2 0.4 75.1 0.5 0.1 0.2 0.6 4.0 1.8 2.7 0.0 0.0 2.8 0.0 5.0 48.7 0.0 13.9 2.1 1.2 1.1 0.0 0.0 0.0 0.6 25.0 0.0 0.0 0.0 1.5 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 13.9 0.3 3.5 1.8 14.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 6.1 0.0 3.1 0.0 27.4 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.2 21.8 4.3 8.1 16.9 0.1 0.0 0.0 24.8 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 17.2 3.8 6.3 6.7 7.8 15.2 5.8 28.3 4.6 3.2 75.1 2.7 0.2 0.0 0.0 46.4 3.1 0.5 6.5 0.4 0.0 59.7 0.1 0.0 0.9 0.0 0.2 7.3 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.1 0.8 0.9 0.0 0.0 122.1 0.0 0.0 2.8 0.0 0.4 0.0 6.1 0.4 0.0 0.0 0.0 162.5 0.0 6.1 0.0 1.3 1.8 8.1 0.0 1.8 18.7 0.0 1.0 0.0 425.3 2.5 0.3 0.0 0.0 1.0 1.1 0.0 0.0 0.0 2.9 6.6 0.2 2.7 0.2 1.1 0.1 0.6 0.0 0.1 7.2 0.0 4.3 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 11.2;intestine: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.4;Cardiomyocytes: 1.1;Excitatory neurons: 1.6;Inhibitory neurons: 1.3;Kupffer cells: 2.9;Microglial cells: 1.0;monocytes: 1.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 7 "midbrain: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "PC-3: 57.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050299 Supported "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" 0.0 0.0 1.1 0.0 1.5 0.6 0.0 0.0 1.4 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 2.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 2.8 0.2 2.7 0.3 1.1 57.7 1.8 0.0 9.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 0.0 1.4 1.4 0.4 0.4 11.2 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 4.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.9 0.3 0.0 0.0 0.5 0.0 1.0 1.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 NUDCD3 "KIAA1068, NudCL" ENSG00000015676 "NudC domain containing 3" Q8IVD9 7 44379119-44490658 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019136, HPA019528, HPA019529" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA019136: AB_1852370, HPA019528: AB_1852372, HPA019529: AB_1852374" "unprognostic (3.72e-2)" "unprognostic (9.28e-3)" "unprognostic (2.33e-2)" "unprognostic (2.05e-3)" "unprognostic (2.18e-3)" "unprognostic (2.05e-2)" "unprognostic (4.73e-2)" "unprognostic (2.30e-2)" "unprognostic (2.18e-1)" "unprognostic (3.96e-2)" "unprognostic (2.28e-1)" "unprognostic (5.62e-2)" "prognostic favorable (9.16e-4)" "unprognostic (3.51e-2)" "unprognostic (1.58e-2)" "unprognostic (1.45e-1)" "unprognostic (6.50e-2)" 2.9 2.8 6.8 1.3 9.0 2.8 2.8 3.2 7.2 2.5 0.0 2.4 1.2 2.2 2.4 2.7 3.5 2.2 7.5 6.6 5.1 2.2 1.8 2.4 2.2 4.4 5.5 3.1 3.3 3.7 1.8 1.7 5.6 2.8 1.8 4.8 2.4 3.3 8.2 3.1 2.0 3.0 3.9 1.9 2.7 3.9 5.6 2.1 2.7 5.7 2.2 2.3 1.8 6.3 2.6 4.9 3.4 6.3 4.2 3.4 1.3 4.1 4.0 4.8 4.9 3.3 1.8 8.1 3.0 5.5 6.6 3.0 4.8 5.6 2.8 4.8 4.9 2.2 2.9 2.3 3.8 3.9 1.3 3.1 3.7 3.6 4.1 2.8 5.9 2.4 6.1 2.6 3.6 2.3 1.6 3.7 4.3 2.5 6.3 2.3 3.7 3.0 2.7 4.0 3.6 10.6 2.4 4.5 1.8 3.4 3.4 5.7 5.7 3.3 3.4 2.2 3.3 7.3 8.1 4.0 3.6 4.5 5.9 0.6 0.8 0.9 1.0 0.8 1.1 1.0 0.9 0.9 0.7 1.0 0.9 0.9 0.5 0.8 1.0 0.6 1.0 0.9 6.8 9.0 3.2 7.2 6.6 5.1 4.4 5.5 5.6 3.9 5.6 6.3 30.5 12.8 19.2 35.9 26.4 11.3 13.0 16.5 20.5 40.9 29.3 25.3 44.5 17.2 16.0 38.6 54.2 19.6 21.9 22.7 23.5 29.6 87.7 27.4 34.4 25.3 17.4 22.3 59.6 21.6 18.1 23.9 23.9 30.9 9.5 35.8 22.5 32.8 18.3 48.8 58.8 25.1 26.4 17.9 9.5 98.3 30.4 13.9 16.0 46.9 21.2 24.8 34.0 36.2 61.2 27.4 18.8 28.2 14.3 15.9 27.2 26.8 21.9 40.2 32.9 17.8 25.2 106.6 21.1 25.5 16.2 14.4 26.2 18.9 27.8 13.3 NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693694-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA044186: AB_10968571, HPA063605: AB_2685058" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (3.14e-1)" "prognostic favorable (2.79e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (6.12e-3)" "unprognostic (6.81e-2)" "prognostic favorable (1.02e-6)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (6.81e-3)" 19.7 46.4 43.1 12.0 44.8 22.2 21.5 43.6 52.5 23.1 45.6 28.5 21.7 21.4 15.3 28.9 23.4 8.4 58.2 44.1 42.0 43.4 64.1 17.2 17.9 45.3 43.2 22.7 24.6 20.4 39.9 8.0 41.9 34.8 11.9 14.5 26.6 14.7 25.0 25.2 29.2 8.5 43.3 33.7 30.1 22.8 44.3 18.2 30.8 16.9 13.1 22.7 21.8 45.7 14.7 23.8 21.2 28.7 15.7 12.1 19.4 17.2 12.9 20.4 12.8 26.9 11.6 15.2 24.4 20.7 10.3 16.8 23.1 23.4 9.5 22.6 38.9 16.8 21.1 32.8 17.0 24.4 19.2 18.7 21.3 17.2 10.7 13.9 15.1 22.6 31.2 18.5 20.1 57.3 36.8 36.0 33.6 24.4 27.0 50.9 22.4 24.2 24.8 18.0 41.8 31.5 25.1 25.9 11.7 16.5 38.4 56.4 20.0 16.7 25.3 39.8 15.9 32.1 20.5 26.1 10.4 32.3 34.8 56.6 54.3 96.2 52.6 48.2 63.1 60.7 63.4 62.8 50.2 65.3 74.0 63.5 68.2 63.9 53.5 83.6 78.3 98.1 43.1 44.8 43.6 52.5 44.1 42.0 45.3 43.2 41.9 43.3 44.3 45.7 23.3 16.0 22.4 14.4 32.6 14.0 19.7 37.4 27.9 52.1 36.0 36.2 52.6 24.3 28.0 42.3 10.4 53.8 43.6 47.7 109.5 28.7 5.2 28.7 33.6 21.4 43.1 23.1 10.2 30.9 31.8 24.0 30.5 29.0 27.9 31.7 17.9 41.8 40.9 47.1 11.8 51.7 89.5 18.3 18.7 8.7 31.4 20.8 30.2 3.7 43.3 83.5 34.0 9.5 15.0 30.0 48.5 50.0 33.0 17.9 77.8 98.2 20.1 58.3 46.0 14.2 22.8 14.8 34.7 24.9 16.6 49.1 43.6 58.0 51.4 17.6 NUDT9 MGC3037 ENSG00000170502 "Nudix hydrolase 9" Q9BW91 4 87422573-87459455 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPTEC TERT1: 160.7" "Low region specificity" "Detected in all" "HPA036917, HPA044866, HPA078535" Approved Approved "Nuclear membrane,Nuclear bodies,Cell Junctions,Mitochondria" "Intracellular and membrane" NA NA 9900 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nuclear bodies, Mitochondria" "Nuclear membrane, Cell Junctions" "HPA036917: AB_10696790, HPA044866: AB_2679120, HPA078535: AB_2686885" "unprognostic (7.22e-2)" "unprognostic (2.59e-2)" "unprognostic (1.45e-2)" "prognostic favorable (7.43e-5)" "unprognostic (2.05e-2)" "unprognostic (1.36e-1)" "unprognostic (1.33e-1)" "unprognostic (3.47e-2)" "unprognostic (2.04e-1)" "unprognostic (1.02e-1)" "unprognostic (1.09e-2)" "unprognostic (4.23e-1)" "prognostic favorable (8.00e-11)" "unprognostic (1.21e-1)" "unprognostic (1.99e-1)" "unprognostic (1.19e-1)" "unprognostic (5.77e-3)" 23.6 36.1 20.8 16.2 21.4 6.7 19.7 25.5 38.5 27.6 39.1 27.0 42.6 24.8 32.2 19.6 24.9 16.2 28.8 21.9 24.7 40.4 46.6 23.0 13.7 21.0 20.5 26.7 67.6 55.3 29.1 19.9 21.9 30.4 27.1 20.1 28.1 23.8 42.1 16.6 40.3 23.8 19.6 14.7 22.3 22.5 22.1 13.4 28.8 45.0 14.8 22.4 24.3 26.0 30.8 25.6 34.0 19.8 67.6 39.6 26.0 59.8 35.6 21.3 21.1 17.1 53.1 47.6 58.9 47.6 41.0 21.1 32.1 38.1 33.2 34.5 24.0 13.4 34.5 31.8 42.4 25.6 21.2 41.5 52.4 25.6 22.6 45.5 41.6 13.7 40.3 30.0 38.7 33.4 39.1 23.2 29.1 68.5 12.0 45.0 31.8 27.0 160.7 24.2 41.3 28.7 37.6 63.0 30.8 44.5 36.8 38.2 43.7 34.7 34.3 25.8 27.8 21.5 18.7 37.9 51.3 21.9 48.2 1.6 17.9 5.9 19.1 21.2 18.2 22.2 18.5 19.5 21.4 18.8 22.5 26.0 1.8 15.6 24.0 20.6 19.0 16.0 20.8 21.4 25.5 38.5 21.9 24.7 21.0 20.5 21.9 19.6 22.1 26.0 32.6 67.3 44.8 20.2 14.9 9.9 40.4 45.0 9.6 15.3 11.3 13.1 40.9 30.0 55.0 23.9 27.1 33.2 13.1 21.0 41.1 44.7 28.6 26.0 26.2 25.8 16.8 6.7 21.7 36.5 32.5 29.4 8.6 27.0 20.8 23.3 18.2 47.5 33.2 6.7 24.0 18.0 40.7 12.7 11.0 11.5 25.4 14.7 10.6 20.6 16.4 26.8 8.2 18.6 24.8 29.4 37.0 26.7 15.8 32.9 55.7 56.2 41.0 18.6 26.3 36.9 23.7 44.5 23.6 15.7 9.5 37.6 12.1 29.8 24.9 27.3 NUMB C14orf41 ENSG00000133961 "NUMB endocytic adaptor protein" P49757 14 73275107-73458617 "Cancer-related genes, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 290.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002874, CAB011478" Approved Enhanced "Cell Junctions" NA NA 12000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "CAB011478: AB_443023, HPA002874: " "unprognostic (5.28e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-1)" "unprognostic (1.32e-3)" "unprognostic (2.02e-1)" "unprognostic (2.01e-1)" "unprognostic (2.43e-1)" "unprognostic (9.49e-2)" "unprognostic (1.33e-2)" "unprognostic (4.08e-3)" "unprognostic (2.65e-3)" "unprognostic (4.14e-2)" "prognostic favorable (2.32e-6)" "unprognostic (9.12e-2)" "unprognostic (1.63e-1)" "unprognostic (3.92e-2)" "unprognostic (2.87e-1)" 35.6 25.9 17.3 37.7 19.2 35.5 33.0 20.4 23.4 34.3 22.0 46.3 46.6 35.6 25.9 40.0 39.0 41.7 28.8 20.9 17.6 41.3 52.1 52.8 24.7 20.3 19.5 33.9 37.3 40.5 20.2 44.4 19.7 29.5 42.2 20.4 36.8 31.6 21.1 32.6 47.4 37.6 18.1 40.4 36.8 20.3 19.4 27.6 39.0 24.1 30.9 40.5 34.0 18.2 70.2 46.9 33.3 30.2 65.8 99.6 45.3 64.9 87.2 51.2 54.1 57.0 86.0 31.9 39.7 80.7 37.8 45.2 39.8 66.6 77.2 48.9 22.2 25.5 28.2 37.3 69.7 23.7 57.5 56.0 70.3 126.2 74.8 56.2 112.3 49.2 47.0 37.1 65.6 62.9 43.3 32.8 15.4 78.9 50.1 27.6 46.7 21.6 71.2 105.3 13.6 35.3 81.0 54.2 33.4 55.9 81.3 34.5 108.8 76.2 42.7 49.3 28.2 30.9 38.9 29.2 153.1 27.4 34.3 91.9 93.3 96.8 12.6 76.4 13.2 22.6 12.7 14.0 68.7 21.4 12.9 11.8 290.3 12.8 102.8 12.8 17.9 64.5 17.3 19.2 20.4 23.4 20.9 17.6 20.3 19.5 19.7 18.1 19.4 18.2 54.4 64.1 49.0 108.4 53.6 42.8 27.7 38.6 42.1 30.7 38.4 26.0 22.0 44.3 50.0 55.2 81.3 26.0 29.9 59.3 25.4 27.9 11.9 68.2 35.0 59.2 40.7 22.9 151.1 26.4 31.0 37.5 43.8 56.6 24.1 26.3 52.1 51.0 42.6 15.2 78.8 39.4 36.7 91.5 109.7 8.1 45.1 94.1 46.2 141.5 117.3 42.6 39.1 62.4 81.8 46.9 39.3 36.9 40.9 37.1 64.7 43.2 56.9 46.4 26.3 22.8 29.7 59.2 32.7 35.6 46.5 34.3 25.6 16.7 37.5 44.6 NUP35 MP44 ENSG00000163002 "Nucleoporin 35" Q8NFH5 2 183117513-183161680 "Metabolic proteins, Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 7 "Early spermatids: 151.6;Late spermatids: 424.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018401, HPA018410, HPA018441" Enhanced Supported "Nucleoplasm,Nuclear membrane,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Nuclear membrane" "Plasma membrane" "HPA018401: AB_1854719, HPA018410: AB_1854721, HPA018441: AB_1854720" "unprognostic (6.18e-3)" "unprognostic (3.15e-1)" "unprognostic (1.83e-1)" "unprognostic (3.58e-3)" "unprognostic (1.37e-1)" "unprognostic (9.91e-2)" "prognostic unfavorable (5.02e-4)" "unprognostic (3.95e-1)" "unprognostic (6.21e-3)" "prognostic favorable (3.45e-4)" "unprognostic (2.32e-2)" "unprognostic (1.61e-3)" "unprognostic (1.78e-3)" "unprognostic (6.78e-2)" "unprognostic (3.47e-2)" "unprognostic (1.24e-1)" "unprognostic (3.96e-2)" 7.7 8.9 5.9 6.9 7.3 4.6 13.1 8.9 7.8 8.5 5.0 7.6 6.3 8.1 7.7 8.7 8.9 6.9 6.2 6.1 5.9 10.2 14.4 5.9 9.1 5.5 5.9 10.4 10.2 8.9 6.3 7.8 5.5 7.8 9.1 9.0 8.4 7.0 7.4 9.0 6.5 8.9 6.6 5.7 7.2 24.2 5.5 10.4 8.2 8.7 11.0 9.2 8.0 6.4 19.7 19.7 32.5 20.5 11.8 11.5 23.2 23.0 18.8 35.3 33.5 37.6 24.7 34.6 22.0 12.4 40.9 17.4 45.4 26.7 57.8 29.6 27.8 32.6 16.4 43.9 8.2 23.6 21.8 8.2 13.8 29.9 28.9 7.9 20.8 20.5 28.7 25.3 27.8 23.7 28.7 29.1 57.9 31.6 61.9 34.3 25.2 25.0 34.0 24.7 29.4 20.3 21.6 26.6 26.0 24.4 17.0 16.2 10.6 28.6 19.7 23.3 26.5 16.4 38.3 37.9 19.3 16.8 39.2 0.0 4.1 1.4 4.9 5.5 8.6 7.2 6.3 6.0 3.2 6.5 7.5 6.7 0.2 5.6 6.6 3.1 6.7 4.1 5.9 7.3 8.9 7.8 6.1 5.9 5.5 5.9 5.5 6.6 5.5 6.4 9.6 9.6 6.8 6.5 10.3 26.0 20.7 17.5 12.5 10.8 9.3 8.9 4.7 14.3 13.8 16.5 18.8 23.6 8.5 3.3 11.7 15.5 151.6 5.3 8.1 10.2 3.6 12.6 11.5 12.7 20.2 10.8 5.1 6.4 8.2 8.1 12.8 12.6 8.4 6.7 12.0 7.5 16.2 4.4 9.9 424.7 9.6 3.6 21.4 2.8 5.0 11.4 7.2 17.1 12.8 11.1 5.1 8.2 7.5 12.8 4.2 14.5 6.9 19.1 13.1 18.7 11.6 39.8 21.1 11.3 27.4 9.4 11.5 9.0 9.6 11.2 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 17.8 20.0 12.1 22.2 13.0 19.4 22.2 11.4 15.5 60.3 16.1 19.8 16.5 20.6 28.4 15.7 18.4 16.1 11.7 12.9 13.8 28.4 31.6 18.2 21.4 10.8 12.5 16.5 20.4 29.8 11.9 21.6 11.9 20.6 20.3 12.5 30.5 17.6 10.0 11.1 17.6 18.7 11.7 17.8 24.2 12.6 13.5 18.5 35.4 12.6 20.6 23.5 11.7 12.4 27.1 19.5 41.3 46.4 40.7 52.9 101.0 48.3 50.1 39.5 45.1 44.6 29.5 63.4 51.1 44.7 50.0 24.0 62.1 47.2 73.0 47.9 57.0 72.8 31.5 80.2 62.6 92.8 41.2 46.6 52.5 43.3 87.7 40.3 41.3 46.5 88.4 54.9 59.7 30.5 43.9 58.8 48.0 36.9 35.3 41.7 29.7 45.7 79.0 26.6 48.7 38.5 29.1 37.4 36.9 45.6 23.8 95.9 36.4 24.3 30.1 39.2 70.5 75.6 60.8 66.8 57.6 70.0 49.7 1.9 1.3 0.8 1.3 1.4 1.9 1.1 1.6 1.8 1.5 1.0 1.3 1.7 0.1 1.9 2.5 3.8 1.7 1.0 12.1 13.0 11.4 15.5 12.9 13.8 10.8 12.5 11.9 11.7 13.5 12.4 18.7 0.0 22.3 30.3 28.5 60.5 41.9 32.6 19.4 15.3 26.6 13.7 6.3 15.7 24.0 25.8 10.4 26.8 38.1 26.4 27.4 23.4 16.0 15.7 28.9 24.3 13.1 19.1 33.4 30.2 63.6 22.8 38.2 21.4 31.1 15.8 28.2 39.7 35.3 15.2 37.1 29.3 20.3 37.0 42.2 14.0 18.0 30.2 32.0 20.6 28.4 8.3 24.7 35.7 36.5 37.4 22.7 20.3 57.5 73.1 18.6 33.6 23.1 9.6 6.6 21.3 25.9 24.9 25.4 25.7 56.1 57.9 26.2 14.5 26.1 77.5 OAS3 ENSG00000111331 "2'-5'-oligoadenylate synthetase 3" Q9Y6K5 12 112938051-112976460 "Enzymes, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "Nucleotidyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "monocytes: 30.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 15.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 202.5;BJ hTERT+ SV40 Large T+ RasG12V: 224.5;GAMG: 89.8;RT4: 62.6" "Not detected" "Not detected" "HPA041253, HPA041372" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" Yes No 21000 "Cluster 51: Monocytes - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041253: AB_10794990, HPA041372: AB_10795590" "unprognostic (8.47e-2)" "unprognostic (9.13e-2)" "unprognostic (1.27e-2)" "unprognostic (4.39e-3)" "unprognostic (2.59e-2)" "unprognostic (1.45e-1)" "unprognostic (4.14e-3)" "unprognostic (8.06e-3)" "unprognostic (3.19e-1)" "unprognostic (1.73e-2)" "unprognostic (2.29e-3)" "unprognostic (2.48e-1)" "prognostic unfavorable (2.23e-5)" "unprognostic (4.25e-2)" "unprognostic (1.37e-2)" "unprognostic (3.29e-2)" "unprognostic (2.93e-2)" 8.1 4.1 3.2 11.5 3.1 20.9 6.0 2.3 2.5 11.0 1.1 7.1 7.1 3.9 1.5 15.8 5.2 11.3 7.0 2.2 2.4 5.6 4.4 12.6 6.0 8.7 3.6 3.8 3.8 3.2 3.5 11.1 6.4 3.4 6.2 0.6 27.7 2.7 3.0 5.4 6.5 9.3 11.8 17.9 11.0 2.3 4.1 16.1 4.1 5.9 6.4 14.4 7.8 3.0 23.2 34.4 0.3 5.5 1.0 4.6 2.1 2.6 25.3 202.5 224.5 24.1 20.5 0.7 7.3 8.1 89.8 15.7 3.3 22.7 11.2 9.7 1.2 15.9 16.3 4.0 3.9 4.5 6.6 0.9 7.2 32.8 1.3 4.0 11.7 3.9 0.5 3.1 2.0 13.3 8.0 2.7 1.4 33.7 22.8 13.5 11.6 0.1 7.0 62.6 0.6 0.1 19.8 5.5 14.8 0.2 25.7 1.1 9.5 4.6 4.0 5.5 6.5 0.8 21.0 0.2 4.9 12.9 16.7 1.0 7.8 0.8 1.4 7.4 1.7 2.3 2.0 2.3 4.1 1.0 1.8 1.7 9.7 2.7 15.3 0.3 2.6 3.5 3.2 3.1 2.3 2.5 2.2 2.4 8.7 3.6 6.4 11.8 4.1 3.0 19.9 3.2 3.9 0.7 3.8 3.4 5.6 13.5 5.2 0.4 3.1 2.7 1.7 0.0 5.1 3.7 0.0 5.4 1.8 14.7 3.9 11.2 5.9 1.8 4.1 20.8 1.8 0.8 0.3 9.8 20.9 5.5 16.3 5.6 1.3 21.9 9.3 1.7 18.7 0.0 0.4 6.8 8.2 5.8 7.0 10.8 10.2 16.7 1.8 5.6 30.2 3.0 8.2 3.5 0.0 21.2 8.2 15.1 1.4 11.8 4.5 2.0 2.3 0.5 0.0 2.5 5.0 0.8 0.7 14.4 4.7 1.9 6.5 9.2 5.4 26.8 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208044-228378876 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 481.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 155.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 10.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA 4500000 "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 3.5 2.5 2.4 1.4 18.4 1.6 3.7 10.4 4.4 8.1 18.1 5.2 0.7 3.7 1.8 4.6 5.1 1.1 78.5 0.9 2.7 6.6 1.3 8.9 2.1 4.3 2.7 8.6 5.4 1.1 13.6 0.9 2.4 9.9 0.5 0.8 9.4 1.7 481.3 4.7 5.4 0.5 1.0 9.3 5.2 1.9 6.3 4.9 7.5 112.8 1.3 3.2 7.4 0.1 1.7 2.8 3.6 3.7 0.2 0.2 4.6 1.6 0.7 1.7 1.4 2.1 1.3 3.2 5.4 0.7 0.7 2.1 1.3 2.2 0.3 2.0 3.4 1.7 10.5 0.1 1.2 2.4 2.2 1.4 0.6 0.4 0.5 5.1 0.5 7.0 3.2 0.0 0.3 1.8 3.3 3.5 4.9 0.6 2.1 4.4 0.0 1.9 1.8 1.4 1.7 6.3 0.6 3.9 1.0 0.8 3.4 4.0 1.0 0.0 5.1 0.3 0.5 2.5 0.5 4.7 0.0 0.8 2.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 2.4 18.4 10.4 4.4 0.9 2.7 4.3 2.7 2.4 1.0 6.3 0.1 1.5 0.0 5.5 1.6 2.4 2.2 6.6 7.7 23.9 4.2 7.3 11.9 155.8 4.3 4.5 5.5 10.4 0.1 1.9 0.7 11.7 3.6 4.9 3.9 3.7 3.1 0.0 3.0 3.9 0.5 0.5 5.7 3.1 11.3 7.0 1.8 1.4 0.5 0.1 0.0 5.3 2.7 4.1 0.3 1.0 4.5 3.1 1.1 1.8 5.6 0.5 7.9 4.1 1.5 1.7 0.8 1.1 4.5 1.5 3.8 0.6 4.1 1.3 3.2 0.0 22.9 6.1 1.0 4.1 9.4 1.7 1.2 5.4 6.2 1.2 3.6 OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 28.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 30.9;Inhibitory neurons: 40.8;Melanocytes: 42.7;Peritubular cells: 14.7" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 24.6" "Low region specificity" "Detected in some" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" 0.3 0.0 1.8 0.1 1.8 0.0 0.3 0.1 1.8 1.2 28.1 0.1 0.0 0.2 0.3 2.2 1.1 0.0 0.3 1.4 1.8 0.3 0.1 0.6 1.8 0.5 0.9 0.3 0.0 0.0 0.8 1.5 0.6 0.6 0.0 0.0 0.8 1.0 0.2 6.4 0.2 0.0 0.0 1.1 0.1 1.9 2.4 0.4 4.2 0.0 0.7 0.2 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 5.6 0.0 0.0 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 0.1 1.8 1.4 1.8 0.5 0.9 0.6 0.0 2.4 1.0 0.0 0.0 0.0 0.7 0.0 2.0 0.1 0.1 0.6 0.0 0.0 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.4 5.6 0.2 0.1 0.0 0.0 30.9 0.0 0.1 1.4 0.0 2.8 0.0 2.3 0.0 0.0 0.1 0.0 40.8 0.1 0.0 0.0 0.9 3.0 9.3 0.1 42.7 0.0 0.0 0.0 0.0 2.5 0.8 0.0 1.2 14.7 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.8 4.2 4.9 6.1 0.9 0.1 0.1 0.4 0.1 0.2 OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 31.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Glandular and luminal cells: 119.7;Urothelial cells: 224.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "A-431: 23.3;CAPAN-2: 39.8;HaCaT: 33.4;RPTEC TERT1: 25.7;SK-BR-3: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" 1.2 0.7 6.2 1.6 6.5 1.8 7.8 7.2 6.7 6.8 22.2 11.0 10.3 2.1 4.0 11.6 7.5 8.5 1.5 5.9 5.4 11.0 18.8 15.1 0.6 9.3 7.7 2.3 20.2 8.3 3.4 3.9 8.3 3.5 11.2 2.3 6.7 4.6 0.6 11.3 10.0 0.6 5.4 2.1 15.2 2.4 6.5 0.9 31.4 0.6 2.8 5.0 7.9 7.4 23.3 4.5 0.6 0.9 0.6 0.9 15.1 0.3 1.6 2.5 3.3 20.7 39.8 0.5 5.9 1.1 8.3 33.4 7.2 4.3 7.8 0.3 12.2 2.4 1.1 9.8 0.3 1.2 2.5 0.1 6.4 4.1 1.0 1.6 1.4 3.1 0.1 0.4 0.1 22.4 1.5 1.2 3.1 8.0 2.1 0.2 6.0 1.1 25.7 22.2 2.7 2.8 0.3 27.2 0.9 5.0 14.7 4.0 1.2 0.4 7.7 1.8 2.7 0.5 0.4 0.3 0.3 0.3 0.6 1.0 0.2 0.5 0.2 0.1 0.2 0.3 0.2 0.1 0.1 0.4 0.2 0.2 2.7 0.5 0.1 0.4 0.1 0.1 6.2 6.5 7.2 6.7 5.9 5.4 9.3 7.7 8.3 5.4 6.5 7.4 4.8 109.0 67.3 1.6 3.2 3.7 60.8 7.6 1.8 5.7 49.7 16.9 1.4 64.3 51.0 25.8 14.6 30.3 3.6 94.1 9.8 65.6 1.9 78.5 12.1 10.7 26.3 2.5 1.3 61.6 2.5 5.8 46.4 119.7 2.5 6.5 18.2 48.3 3.0 6.7 1.1 45.1 16.2 12.9 1.2 1.6 3.1 2.4 1.8 16.9 3.9 2.8 1.0 0.5 1.5 64.6 61.8 1.5 1.1 101.5 42.3 10.5 63.0 6.3 13.1 3.3 4.4 4.7 8.2 29.5 15.5 16.4 4.3 0.7 47.9 224.0 OCM OCM1 ENSG00000122543 Oncomodulin P0CE72 7 5879827-5886363 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 2.3;Excitatory neurons: 8.6;Inhibitory neurons: 7.0;Late spermatids: 2.4;Microglial cells: 4.7;Oligodendrocytes: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA046422: AB_2679659, HPA052483: " "unprognostic (1.79e-2)" "unprognostic (2.55e-2)" "unprognostic (3.97e-1)" "unprognostic (1.50e-1)" "unprognostic (5.39e-2)" "unprognostic (1.31e-2)" "unprognostic (2.30e-2)" "unprognostic (7.62e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-1)" "unprognostic (1.92e-3)" "unprognostic (6.13e-2)" "unprognostic (2.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.02e-1)" "unprognostic (3.23e-1)" "unprognostic (3.90e-4)" 0.2 0.2 2.9 0.3 2.1 0.7 0.5 2.3 3.2 0.4 1.6 0.2 0.0 0.1 0.9 0.2 0.3 0.2 0.1 2.1 2.4 0.3 0.3 0.2 2.1 1.9 2.0 0.3 0.2 0.0 0.3 0.0 2.0 0.3 0.2 0.6 0.3 0.3 0.1 0.7 0.7 0.1 1.8 1.2 0.2 2.1 2.4 0.8 0.3 0.0 0.8 0.1 0.3 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.8 0.4 0.2 0.1 0.4 1.1 0.3 0.0 1.4 1.5 0.4 0.6 0.0 0.2 0.0 2.7 0.4 2.9 2.1 2.3 3.2 2.1 2.4 1.9 2.0 2.0 1.8 2.4 2.2 0.1 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 7.0 0.0 0.0 0.6 0.0 2.4 0.0 0.1 0.0 4.7 0.3 0.5 1.0 1.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 OCM2 ENSG00000135175 "Oncomodulin 2" P0CE71 7 97984684-97991169 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA046422: AB_2679659, HPA052483: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448327 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 560.8;Late spermatids: 834.9;Prostatic glandular cells: 412.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 47.2 23.2 31.0 69.3 31.5 172.9 33.0 30.5 32.2 33.5 48.5 64.8 32.4 66.0 49.2 29.4 56.3 43.7 55.9 29.9 33.0 132.2 92.1 52.4 111.0 32.4 33.0 54.8 61.8 99.6 92.5 20.0 30.6 91.1 72.0 46.2 27.0 55.1 163.3 29.2 41.6 71.2 34.1 42.9 51.5 133.3 34.0 77.1 58.5 73.5 149.1 113.6 26.9 35.7 166.8 130.6 177.1 211.4 31.1 92.4 410.1 234.6 114.9 216.3 99.9 697.3 75.4 870.2 114.6 143.6 208.6 30.2 549.1 265.5 261.2 334.0 231.5 398.1 212.2 429.9 250.8 680.1 91.8 62.5 70.5 490.1 608.3 111.4 176.3 237.6 674.2 274.3 121.7 109.0 680.1 267.3 324.9 228.3 418.8 478.5 556.0 586.3 130.9 119.5 246.6 209.9 293.6 88.8 121.8 135.7 60.0 300.5 124.7 174.4 362.6 227.9 511.7 128.0 416.1 780.8 156.7 443.6 109.9 0.0 1.5 3.0 2.9 2.9 3.3 14.8 4.1 4.8 3.4 15.0 2.8 4.5 0.5 1.4 1.8 12.2 4.4 3.2 31.0 31.5 30.5 32.2 29.9 33.0 32.4 33.0 30.6 34.1 34.0 35.7 78.2 44.8 161.4 7.5 228.9 58.0 123.7 48.8 19.4 36.8 53.2 68.3 55.1 81.5 33.9 40.5 31.3 1.5 188.1 77.7 72.4 50.6 560.8 90.9 66.2 52.2 271.0 111.3 7.5 27.6 70.0 63.2 204.4 127.6 58.9 103.8 14.6 50.3 46.8 6.7 4.1 234.1 22.4 32.1 22.4 834.9 15.5 191.8 23.2 8.4 22.1 126.3 37.0 4.5 2.4 28.6 64.5 11.3 287.4 412.4 31.6 154.1 21.9 77.4 0.0 223.0 79.9 186.5 75.8 52.2 87.5 3.4 133.0 30.2 180.5 142.2 ODR4 "C1orf27, FLJ20505, odr-4, TTG1" ENSG00000157181 "Odr-4 GPCR localization factor homolog" Q5SWX8 1 186375838-186421378 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 37.8;Glandular and luminal cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015988, HPA031352" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane" "HPA015988: AB_1845644, HPA031352: AB_2673838" "unprognostic (1.19e-2)" "unprognostic (4.23e-2)" "unprognostic (1.12e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" "unprognostic (8.57e-2)" "unprognostic (8.11e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.15e-2)" "unprognostic (9.85e-2)" "unprognostic (2.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (4.20e-2)" 11.9 14.4 7.5 7.2 9.2 15.0 14.0 10.4 10.1 13.3 8.4 10.8 13.4 9.4 17.2 7.8 8.8 10.6 10.0 7.6 8.2 16.7 21.8 9.5 6.7 8.9 8.6 10.3 29.1 32.4 12.4 14.2 9.2 16.6 12.7 15.2 21.7 12.2 9.0 10.3 13.6 8.8 8.7 8.5 13.1 8.3 8.2 6.4 19.9 9.5 7.1 11.5 8.2 11.9 12.6 13.9 15.1 12.1 17.5 16.3 28.8 19.9 12.2 12.7 12.8 28.2 29.7 8.7 23.5 9.9 11.6 32.3 11.4 10.9 12.5 7.1 10.9 8.2 17.7 15.9 16.4 13.8 9.6 12.5 21.3 15.4 24.1 13.2 13.8 9.0 32.1 17.3 15.3 13.5 9.7 14.3 21.6 46.0 5.0 11.2 10.5 25.0 26.1 12.9 11.0 17.2 15.1 33.0 24.5 26.9 29.1 12.4 13.2 18.1 11.5 12.2 18.9 20.2 13.3 13.3 9.8 7.4 16.7 1.4 9.0 2.5 3.0 8.9 4.5 3.6 3.8 4.2 7.6 2.3 4.7 3.6 3.9 10.0 11.4 4.8 5.7 3.9 7.5 9.2 10.4 10.1 7.6 8.2 8.9 8.6 9.2 8.7 8.2 11.9 28.1 28.9 37.8 0.0 4.2 0.0 0.0 0.0 0.0 0.0 18.8 16.5 0.0 0.0 29.7 25.8 0.0 22.0 12.6 0.0 9.8 22.8 0.0 26.8 27.0 9.8 0.0 0.0 0.0 25.4 25.7 12.3 0.0 38.6 12.6 26.4 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 6.7 0.0 0.0 0.0 0.0 24.7 0.0 0.0 4.0 0.0 0.0 10.7 15.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 28.0 6.9 29.0 0.0 0.0 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533104-71575892 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: AB_2673595" "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favorable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavorable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favorable (6.85e-7)" 59.3 55.9 39.7 38.3 42.4 61.5 62.7 43.3 51.6 72.7 40.1 62.5 30.6 56.0 62.2 52.8 76.4 26.4 55.5 43.9 35.5 61.6 45.8 70.7 71.9 36.1 35.8 85.5 102.4 24.3 46.9 26.4 37.9 75.4 39.6 36.9 64.1 27.1 62.8 68.6 86.4 24.5 36.1 122.8 67.4 19.0 36.2 57.2 70.7 39.2 57.8 55.7 67.4 44.3 40.5 37.0 47.1 41.5 49.6 45.6 31.6 30.3 54.3 32.1 49.1 39.3 45.4 47.9 20.7 37.3 33.3 49.1 52.0 29.5 39.4 41.1 53.4 30.4 98.6 28.5 37.6 62.9 48.1 43.6 59.2 35.1 65.7 55.5 30.5 100.7 31.1 160.4 31.1 34.3 48.9 75.2 31.6 35.5 49.8 47.8 52.7 62.1 50.0 45.9 24.1 21.2 46.9 30.9 30.2 35.5 22.8 42.4 35.5 34.6 27.9 36.6 17.9 43.5 33.5 56.5 24.4 65.0 21.6 2.8 4.6 2.0 7.5 5.7 6.8 7.4 6.3 6.2 6.1 6.2 7.2 7.4 1.9 10.4 5.7 6.2 6.2 5.6 39.7 42.4 43.3 51.6 43.9 35.5 36.1 35.8 37.9 36.1 36.2 44.3 31.1 35.3 85.2 52.9 67.2 88.1 37.9 23.5 58.6 26.5 49.6 34.0 42.8 20.0 31.1 49.7 8.4 15.8 130.7 31.1 9.8 14.4 2.4 32.1 49.8 39.8 34.9 51.3 110.7 14.4 8.5 47.5 54.6 53.3 27.8 26.4 45.7 27.5 16.1 40.4 94.6 37.3 22.4 60.9 69.7 4.8 53.4 45.8 35.6 71.2 51.6 11.3 51.5 92.0 97.9 17.6 34.9 29.7 147.2 53.8 34.8 15.1 28.0 21.8 32.9 44.8 42.2 2.5 6.1 63.3 84.1 10.9 82.1 62.0 34.0 50.8 OLFM4 "GC1, GW112, OlfD" ENSG00000102837 "Olfactomedin 4" Q6UX06 13 53028813-53052057 "Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1296.1;pancreas: 671.4" "Cell type enhanced" "Detected in many" "Ductal cells: 497.1;Exocrine glandular cells: 900.9;Intestinal goblet cells: 791.9;Pancreatic endocrine cells: 933.7;Paneth cells: 556.9;Undifferentiated cells: 2419.9;Urothelial cells: 1989.0" "Group enriched" "Detected in many" 14 "colorectal cancer: 711.4;pancreatic cancer: 594.7;stomach cancer: 724.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 5.4;BJ hTERT+: 18.8;HaCaT: 26.4;OE19: 10.4;RPMI-8226: 6.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA077718 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Cytosol" "Secreted to digestive system" Yes NA 9300 "Cluster 56: Intestine - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Cytokinetic bridge, Cytosol" "HPA077718: AB_2732358" "prognostic favorable (8.77e-4)" "unprognostic (4.84e-2)" "unprognostic (1.65e-3)" "unprognostic (2.33e-1)" "unprognostic (7.24e-2)" "unprognostic (1.34e-1)" "unprognostic (3.74e-2)" "unprognostic (5.16e-2)" "unprognostic (1.40e-1)" "unprognostic (1.22e-1)" "unprognostic (4.78e-2)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "unprognostic (1.29e-2)" "unprognostic (1.33e-1)" "unprognostic (4.37e-2)" "unprognostic (4.84e-3)" 1.9 0.1 0.2 195.4 0.5 126.0 6.8 0.1 0.5 7.9 0.2 451.6 1211.9 5.5 3.5 0.8 8.3 10.4 0.8 0.2 0.4 26.9 0.9 3.8 1.4 0.1 0.2 0.2 671.4 0.0 0.5 0.6 0.2 92.4 568.7 0.4 16.2 0.9 0.6 0.4 1296.1 52.6 0.2 18.0 16.1 0.3 0.2 4.2 0.4 2.1 0.2 127.0 285.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 5.4 2.4 18.8 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 26.4 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.0 0.0 10.4 0.0 0.0 0.8 6.2 0.2 0.0 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.6 0.9 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.5 0.1 0.5 0.2 0.4 0.1 0.2 0.2 0.2 0.2 0.2 0.2 0.0 0.0 0.3 3.8 0.1 168.5 0.3 0.0 0.0 9.8 2.5 0.5 0.0 11.9 139.8 0.0 0.0 0.0 98.7 1.9 497.1 0.2 13.5 0.5 1.4 92.3 0.8 1.0 900.9 0.0 1.5 0.0 17.6 0.0 0.0 0.0 0.0 0.1 0.0 0.3 791.9 2.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 10.3 4.0 0.0 0.0 0.2 933.7 556.9 0.0 0.4 209.4 300.6 0.0 0.5 0.2 0.0 2.1 9.2 0.0 0.1 0.0 0.0 0.0 3.1 0.2 2419.9 1989.0 OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 87.2" "Group enriched" "Detected in some" 22 "Oligodendrocyte precursor cells: 124.1;Oligodendrocytes: 39.9" "Cancer enriched" "Detected in some" 52 "glioma: 46.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cell line enhanced" "Detected in some" "HMC-1: 56.2;NB-4: 41.8;THP-1: 35.9;WM-115: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: AB_1854795" "unprognostic (5.14e-1)" "unprognostic (4.56e-1)" "unprognostic (1.44e-2)" "unprognostic (8.27e-2)" "unprognostic (3.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (5.78e-5)" "unprognostic (2.76e-1)" 0.0 0.0 46.4 0.0 58.3 0.0 0.0 52.7 54.4 0.0 21.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 48.1 49.8 0.0 0.0 0.0 0.0 58.0 54.6 0.0 0.0 0.0 0.1 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 48.0 0.0 0.1 0.0 50.9 0.0 0.0 0.2 0.0 0.0 0.0 87.2 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.5 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.0 1.7 56.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 41.8 3.6 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 35.9 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 1.4 0.0 11.7 2.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 58.3 52.7 54.4 48.1 49.8 58.0 54.6 51.4 48.0 50.9 87.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 124.1 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 OLR1 "CLEC8A, LOX-1, SCARE1" ENSG00000173391 "Oxidized low density lipoprotein receptor 1" P78380 12 10158301-10172138 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity, Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 52.6;lung: 100.2;placenta: 114.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 399.0;Hofbauer cells: 202.1;Macrophages: 202.6;Syncytiotrophoblasts: 463.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 2.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CACO-2: 125.4;HaCaT: 64.9;HHSteC: 125.1;hTCEpi: 58.4;SiHa: 248.8;SK-BR-3: 96.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA050798 Approved "Nucleoplasm,Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1060000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" Vesicles "HPA050798: AB_2756318" "unprognostic (2.30e-1)" "unprognostic (3.16e-2)" "unprognostic (1.58e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "prognostic unfavorable (8.24e-5)" "unprognostic (6.34e-2)" "unprognostic (6.07e-3)" "unprognostic (5.40e-2)" "unprognostic (2.64e-1)" "unprognostic (1.97e-2)" "unprognostic (3.51e-1)" "unprognostic (1.08e-1)" "unprognostic (4.94e-3)" "unprognostic (3.47e-2)" "unprognostic (1.48e-2)" "unprognostic (1.42e-1)" 3.0 3.3 9.0 29.1 13.1 23.8 3.6 18.9 16.9 3.3 8.8 0.7 1.3 1.6 1.3 0.5 2.1 7.4 1.5 9.4 13.3 8.2 3.1 100.2 0.7 25.5 15.6 0.3 2.2 4.1 2.7 114.5 26.0 2.3 1.0 5.1 3.8 1.0 0.5 0.6 1.2 2.1 27.6 0.8 2.3 4.7 24.0 2.8 2.5 0.0 0.8 6.0 0.3 52.6 7.3 0.5 0.1 0.3 0.3 0.0 16.8 12.1 2.2 7.3 2.6 125.4 0.1 1.6 0.0 15.8 0.5 64.9 0.0 0.7 4.9 0.0 0.0 0.0 6.1 0.0 125.1 0.1 0.3 1.0 58.4 0.3 0.0 0.0 0.3 0.1 0.1 0.7 0.0 0.1 0.3 0.2 0.2 0.0 0.0 0.0 0.2 0.3 0.2 13.3 0.4 0.2 248.8 96.9 0.0 17.4 27.1 0.0 0.1 0.2 1.4 0.0 0.0 0.4 0.3 0.4 0.1 0.1 0.1 0.6 0.6 1.3 0.1 0.1 0.1 0.1 0.1 0.0 2.8 0.2 0.1 0.1 1.4 0.1 0.1 0.3 0.1 0.6 9.0 13.1 18.9 16.9 9.4 13.3 25.5 15.6 26.0 27.6 24.0 52.6 1.9 28.9 27.4 0.0 4.0 1.5 0.4 0.5 0.0 0.4 1.1 4.6 0.1 1.5 4.4 0.0 0.0 399.0 0.3 0.0 0.0 0.1 13.4 0.1 0.0 10.8 0.0 0.4 2.3 0.0 14.6 10.9 0.5 0.1 15.2 0.0 0.0 0.5 202.1 0.0 0.2 0.0 0.0 18.9 79.5 11.6 0.3 202.6 0.0 40.3 21.3 0.1 0.0 0.5 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.2 6.6 0.2 0.0 0.2 0.4 0.1 0.2 0.8 0.6 463.1 1.6 0.1 0.0 0.3 OPHN1 "ARHGAP41, MRX60, OPN1" ENSG00000079482 "Oligophrenin 1" O60890 X 67949349-68433913 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Neurogenesis" "GTPase activation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.8" "Group enriched" "Detected in many" 5 "Astrocytes: 383.9;Oligodendrocyte precursor cells: 600.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002919 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Plasma membrane" "HPA002919: AB_1079526" "unprognostic (1.21e-1)" "unprognostic (3.21e-2)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (3.85e-3)" "unprognostic (4.32e-2)" "unprognostic (3.52e-2)" "unprognostic (3.09e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (4.37e-2)" "unprognostic (2.30e-1)" "unprognostic (2.21e-4)" "unprognostic (1.98e-1)" "unprognostic (1.29e-2)" "unprognostic (2.08e-3)" "unprognostic (2.64e-3)" 4.1 5.1 20.8 1.8 18.6 3.9 4.5 14.2 19.5 6.0 1.0 3.4 2.5 5.6 3.7 3.8 3.2 2.7 3.1 18.0 14.6 4.3 1.3 4.4 1.9 9.5 11.9 4.5 3.1 3.6 2.7 5.6 5.8 10.1 3.4 11.5 5.4 5.0 6.5 6.4 2.9 4.0 6.1 2.3 3.8 2.6 16.3 1.2 4.7 4.8 1.4 2.3 3.8 11.5 23.6 5.1 3.2 7.3 7.1 6.8 5.0 4.2 5.6 8.3 10.1 3.3 4.5 1.5 13.7 4.9 3.4 5.7 3.1 2.9 12.6 0.9 2.1 5.2 6.9 3.7 2.4 2.1 5.2 4.6 4.8 6.9 6.4 10.6 5.6 1.1 3.2 3.1 4.3 10.1 0.8 1.8 7.5 10.0 4.8 0.9 7.3 1.3 8.5 7.6 1.7 2.8 7.2 9.1 13.7 7.1 6.2 1.6 6.0 5.0 7.3 18.1 4.5 2.9 3.4 1.0 4.0 2.8 3.5 1.0 1.0 0.4 0.5 0.4 0.4 0.5 0.4 0.3 0.4 0.8 0.4 0.5 4.6 0.5 0.6 1.6 0.3 0.2 20.8 18.6 14.2 19.5 18.0 14.6 9.5 11.9 5.8 6.1 16.3 11.5 13.8 16.0 19.3 383.9 0.0 3.2 5.4 2.0 10.2 5.4 6.7 5.0 3.3 2.8 6.4 18.4 6.2 23.0 2.3 3.9 0.0 1.2 2.0 7.2 4.3 8.1 4.2 1.3 84.6 0.8 11.7 18.0 14.8 12.9 8.8 36.3 5.0 0.2 4.6 0.0 78.8 3.0 2.0 2.1 9.5 1.7 21.1 5.9 8.8 54.4 1.2 16.0 3.1 600.2 41.7 1.3 2.4 12.0 0.1 8.5 3.8 1.8 10.9 5.1 0.0 24.1 5.4 0.3 1.9 8.9 5.1 66.9 1.4 4.2 4.1 4.2 OPRK1 "KOR, OPRK" ENSG00000082556 "Opioid receptor kappa 1" P41145 8 53225724-53251637 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "brain: 14.5" "Group enriched" "Detected in some" 5 "Endometrial ciliated cells: 4.5;Excitatory neurons: 6.7;Extravillous trophoblasts: 8.0;Glandular and luminal cells: 9.8;Inhibitory neurons: 10.1;Leydig cells: 4.7" "Cancer enhanced" "Detected in some" "prostate cancer: 1.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "U-937: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA067549 Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 32: U-937 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA067549: AB_2732770" "unprognostic (1.01e-1)" "unprognostic (1.17e-2)" "unprognostic (8.70e-3)" "unprognostic (3.73e-2)" "unprognostic (6.74e-2)" "unprognostic (2.22e-3)" "unprognostic (8.09e-2)" "unprognostic (9.71e-2)" "unprognostic (4.28e-3)" "unprognostic (3.29e-1)" "unprognostic (3.35e-2)" "unprognostic (9.54e-4)" "unprognostic (1.61e-1)" 0.1 0.1 7.3 0.0 14.5 0.0 0.0 1.3 8.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.9 5.4 0.0 0.0 0.1 0.0 5.8 1.7 0.0 0.0 0.0 0.0 0.2 5.1 1.6 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.7 6.9 0.1 0.1 0.0 0.0 0.0 0.0 2.6 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 21.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 14.5 1.3 8.3 3.9 5.4 5.8 1.7 5.1 0.3 6.9 2.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.6 1.3 0.0 0.0 0.0 0.2 4.5 0.6 0.1 0.0 0.0 6.7 0.0 8.0 0.1 0.0 9.8 0.0 0.0 0.0 0.0 0.2 0.0 10.1 0.0 0.0 0.0 0.0 0.3 4.7 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 OR10P1 "OR10P1P, OR10P2P, OR10P3P, OST701" ENSG00000175398 "Olfactory receptor family 10 subfamily P member 1" Q8NGE3 12 55636860-55637854 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074114 Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA074114: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.8 0.3 0.9 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " "unprognostic (4.88e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.2 0.5 0.5 0.4 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C9 ENSG00000136839 "Olfactory receptor family 13 subfamily C member 9" Q8NGT0 9 104617248-104618204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Uncertain "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.1 0.3 0.4 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2C3 "OR2C4, OR2C5P, OST742" ENSG00000196242 "Olfactory receptor family 2 subfamily C member 3" Q8N628 1 247524677-247536440 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 2.4;granulocytes: 1.3;Late spermatids: 3.7;Spermatocytes: 2.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Immune cell enriched" "Detected in single" 5 "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA058578 Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA058578: AB_2683761" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.03e-1)" 0.0 0.1 0.2 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 1.3 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OR6B2 OR6B2P ENSG00000182083 "Olfactory receptor family 6 subfamily B member 2" Q6IFH4 2 240028965-240030456 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6B3 "OR6B3P, OR6B3Q" ENSG00000178586 "Olfactory receptor family 6 subfamily B member 3" Q8NGW1 2 240045077-240047027 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "retina: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6C6 ENSG00000188324 "Olfactory receptor family 6 subfamily C member 6" A6NF89 12 55293988-55296569 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051090 Uncertain Approved "Lipid droplets,Plasma membrane" NA NA "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Lipid droplets, Plasma membrane" "HPA051090: AB_2681341" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR8S1 ENSG00000284723 "Olfactory receptor family 8 subfamily S member 1" Q8NH09 12 48525632-48528103 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Spermatocytes: 4.0;Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045595 Uncertain Supported "Plasma membrane" NA NA "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" "HPA045595: AB_10964447" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSBPL10 ENSG00000144645 "Oxysterol binding protein like 10" Q9BXB5 3 31657912-32077580 "Predicted intracellular proteins" "Lipid biosynthesis, Lipid metabolism, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 6 "Early spermatids: 440.2;Late spermatids: 1206.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 17 "memory B-cell: 11.5;naive B-cell: 6.7" "Lineage enriched" "Detected in single" 22 "B-cells: 11.5" "Cell line enhanced" "Detected in many" "hTERT-HME1: 93.3;RPTEC TERT1: 118.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003636 Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus, Plasma membrane, Cytosol" "HPA003636: AB_1079529" "unprognostic (5.28e-3)" "unprognostic (2.06e-2)" "unprognostic (4.21e-2)" "unprognostic (1.44e-2)" "unprognostic (1.98e-1)" "unprognostic (2.79e-1)" "unprognostic (3.29e-2)" "unprognostic (3.63e-2)" "unprognostic (8.55e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (3.14e-4)" "unprognostic (2.15e-1)" "prognostic favorable (1.51e-4)" "unprognostic (5.86e-2)" "unprognostic (7.64e-2)" "unprognostic (2.23e-2)" "prognostic unfavorable (4.85e-4)" 8.3 2.6 3.1 7.8 3.0 1.2 6.0 0.1 3.6 10.2 6.5 6.5 3.7 8.4 6.6 13.0 5.9 11.4 2.9 4.8 2.7 13.3 2.2 5.8 12.9 1.2 4.9 3.1 1.6 1.6 6.7 22.3 3.0 11.8 7.8 5.5 6.8 20.9 1.6 4.9 6.7 11.1 0.3 9.5 6.1 25.0 1.3 2.8 3.5 2.2 17.8 20.3 5.9 2.6 19.3 10.6 2.0 39.3 4.2 7.4 63.1 5.2 6.1 4.9 6.8 27.0 14.3 45.6 48.8 1.1 17.0 11.5 8.9 45.1 6.0 0.3 8.2 0.1 26.4 18.3 2.7 0.1 0.2 7.7 39.7 7.8 93.3 18.2 23.4 0.2 0.1 0.2 22.7 16.0 0.2 0.1 24.9 64.9 26.5 0.5 0.8 0.9 118.3 7.8 3.0 0.5 8.9 17.0 5.4 36.9 11.1 0.2 15.2 6.1 61.7 0.5 26.2 4.1 3.0 42.6 8.6 0.1 39.3 0.2 0.0 0.1 0.0 0.0 0.0 11.5 0.0 0.0 0.0 6.7 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.2 3.1 3.0 0.1 3.6 4.8 2.7 1.2 4.9 3.0 0.3 1.3 2.6 20.5 9.6 3.9 2.9 50.6 10.8 7.5 10.1 4.6 7.3 13.8 6.6 2.3 4.3 7.3 7.3 0.0 15.3 2.4 7.9 9.8 1.8 440.2 11.0 26.5 21.1 15.0 5.7 70.5 4.9 25.9 10.4 6.1 26.4 0.0 1.3 18.2 0.6 2.5 0.0 129.9 4.6 6.1 0.9 6.3 1206.2 11.1 2.2 8.8 17.8 1.7 45.7 1.0 12.1 2.3 16.2 9.0 4.1 21.0 18.3 6.1 24.8 6.9 2.3 19.7 4.8 15.6 7.0 4.1 14.4 12.4 30.2 3.5 1.0 8.8 16.3 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 OSBPL7 "MGC71150, ORP7" ENSG00000006025 "Oxysterol binding protein like 7" Q9BZF2 17 47807372-47821834 "Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 29.5;Gastric mucus-secreting cells: 118.7;Paneth cells: 29.9;Proximal enterocytes: 34.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 43.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036076, HPA053083, HPA073967" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 14: B-cells - Humoral immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036076: AB_10601042, HPA053083: AB_2682038, HPA073967: " "unprognostic (3.88e-2)" "unprognostic (2.01e-1)" "unprognostic (2.25e-1)" "unprognostic (1.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.55e-3)" "unprognostic (2.05e-3)" "unprognostic (1.19e-1)" "unprognostic (3.95e-2)" "unprognostic (3.33e-1)" "unprognostic (1.97e-1)" "unprognostic (6.78e-2)" "prognostic unfavorable (8.30e-4)" "unprognostic (2.17e-1)" "unprognostic (1.36e-1)" "unprognostic (3.08e-1)" "prognostic favorable (1.19e-5)" 5.0 3.7 10.6 4.9 10.4 7.2 5.4 9.5 14.0 11.1 7.3 22.7 22.3 8.6 1.6 3.4 7.6 5.3 6.5 10.3 9.9 9.9 2.2 8.5 7.5 10.6 10.2 9.6 17.3 2.6 10.1 2.3 10.7 14.3 8.7 3.1 9.0 6.1 20.2 1.7 22.7 3.5 9.2 17.2 34.0 1.4 10.5 4.9 11.3 3.5 3.8 9.1 7.0 10.9 6.0 6.9 3.0 3.4 3.3 4.6 2.5 2.2 3.2 3.7 4.2 7.1 17.8 6.0 8.7 3.2 1.3 43.2 1.7 4.8 1.2 20.8 2.4 4.4 15.0 4.8 3.0 9.4 0.1 7.4 0.9 2.4 1.7 11.5 7.7 10.5 4.4 8.1 5.8 7.8 9.5 10.0 1.8 23.8 8.9 8.6 4.7 8.3 5.0 4.5 3.1 7.0 3.7 1.2 3.3 3.7 6.4 5.9 8.9 5.6 4.9 0.0 1.8 14.6 5.8 5.8 6.1 7.9 2.2 0.0 0.6 0.6 1.8 0.4 0.8 1.0 0.7 1.1 0.6 0.4 0.5 0.8 0.3 0.4 0.0 1.0 0.9 0.9 10.6 10.4 9.5 14.0 10.3 9.9 10.6 10.2 10.7 9.2 10.5 10.9 5.5 0.0 3.9 10.4 4.5 0.1 1.1 2.5 1.2 6.1 2.9 2.5 2.7 1.5 7.4 3.7 6.2 0.2 15.4 29.5 0.0 2.7 0.1 2.1 2.7 4.3 6.0 3.2 7.3 14.7 0.1 2.0 118.7 1.7 2.5 7.1 5.3 0.5 2.7 11.8 6.3 25.8 4.1 3.4 0.8 0.3 2.8 2.3 1.8 1.0 2.7 7.1 8.2 3.5 9.3 9.3 29.9 2.6 11.4 1.7 34.5 1.2 3.4 8.2 0.0 2.5 1.9 0.0 0.3 1.3 0.1 0.5 10.0 3.3 17.6 1.3 OSCAR ENSG00000170909 "Osteoclast associated Ig-like receptor" Q8IYS5 19 54094668-54102692 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 13.6;lung: 28.4;lymphoid tissue: 29.8" "Cell type enhanced" "Detected in some" "Hofbauer cells: 35.6;Kupffer cells: 27.8;Macrophages: 42.9;monocytes: 66.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 36 "classical monocyte: 43.0;eosinophil: 26.6;intermediate monocyte: 28.8;myeloid DC: 20.3;neutrophil: 40.0;non-classical monocyte: 27.0" "Group enriched" "Detected in many" 79 "dendritic cells: 20.3;granulocytes: 40.0;monocytes: 43.0" "Cell line enhanced" "Detected in some" "EFO-21: 13.9;HHSteC: 9.4;hTERT-HME1: 5.0;NB-4: 5.9;U-937: 17.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA073996 Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 84000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA073996: " "unprognostic (9.09e-2)" "unprognostic (6.79e-3)" "unprognostic (8.47e-3)" "unprognostic (2.14e-1)" "unprognostic (2.12e-2)" "unprognostic (9.04e-2)" "unprognostic (1.39e-1)" "unprognostic (3.86e-1)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.05e-2)" "unprognostic (3.01e-1)" "prognostic unfavorable (2.71e-5)" "unprognostic (1.84e-1)" "unprognostic (2.88e-2)" "unprognostic (9.69e-2)" "unprognostic (4.28e-2)" 3.7 1.8 0.9 2.3 0.7 13.6 1.8 0.1 1.6 2.2 0.0 1.5 0.0 1.3 0.0 1.5 3.2 1.3 1.9 0.1 0.7 1.5 2.4 28.4 0.3 1.3 0.7 1.1 1.3 0.1 1.0 0.6 0.9 1.7 0.3 0.0 2.2 0.3 0.5 2.1 1.6 1.7 0.7 29.8 1.2 0.9 0.8 0.2 1.1 0.6 0.6 2.2 2.1 1.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.3 0.0 13.9 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 9.4 0.6 0.0 0.0 0.2 0.6 5.0 0.8 0.0 0.0 0.0 0.4 0.1 0.1 0.0 5.9 0.3 0.1 1.0 0.0 0.5 0.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 3.8 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.6 0.5 17.9 0.0 0.0 43.0 26.6 0.3 28.8 0.1 0.0 0.2 0.4 20.3 0.0 0.1 0.0 40.0 0.0 27.0 0.8 0.2 16.8 0.9 0.7 0.1 1.6 0.1 0.7 1.3 0.7 0.9 0.7 0.8 1.7 0.2 3.2 5.9 0.3 0.3 0.8 0.6 0.7 0.6 0.0 0.7 0.4 0.3 1.5 2.1 0.0 0.0 0.3 0.6 0.1 0.0 0.3 0.0 0.1 0.3 0.9 0.0 1.7 1.9 0.0 0.4 0.6 0.0 0.1 1.3 0.3 0.0 0.0 35.6 0.0 1.0 0.3 0.0 27.8 11.6 0.2 0.0 42.9 0.0 1.0 66.4 0.0 1.0 0.0 0.3 0.4 0.0 0.0 0.4 0.3 0.1 0.2 3.7 0.4 0.0 0.2 0.1 0.6 0.5 0.4 0.1 0.3 0.7 0.4 0.1 0.3 OSCP1 "C1orf102, NOR1" ENSG00000116885 "Organic solute carrier partner 1" Q8WVF1 1 36415827-36450451 "Predicted intracellular proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "fallopian tube: 58.0;testis: 76.1" "Cell type enhanced" "Detected in many" "Early spermatids: 453.5;Endometrial ciliated cells: 88.6;Respiratory ciliated cells: 199.1;Spermatocytes: 163.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028436, HPA052655" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA028436: AB_10600885, HPA052655: " "unprognostic (3.46e-3)" "unprognostic (7.57e-2)" "unprognostic (4.67e-2)" "prognostic favorable (6.88e-4)" "unprognostic (1.28e-2)" "unprognostic (4.81e-2)" "unprognostic (3.38e-2)" "unprognostic (4.52e-2)" "unprognostic (5.52e-2)" "unprognostic (8.80e-2)" "unprognostic (2.21e-2)" "unprognostic (3.87e-2)" "prognostic favorable (2.18e-6)" "unprognostic (1.20e-1)" "unprognostic (2.04e-2)" "unprognostic (1.02e-2)" "unprognostic (4.20e-2)" 6.8 8.2 9.7 2.4 10.4 2.0 9.4 7.4 10.5 9.5 31.3 7.3 2.9 10.0 22.0 5.0 58.0 8.8 7.9 11.1 13.0 19.1 2.8 11.0 1.9 11.3 14.7 9.1 8.2 30.2 23.1 5.6 10.9 9.9 3.9 23.1 8.7 8.9 4.9 6.8 2.7 7.9 9.9 1.4 6.3 76.1 13.5 3.6 17.9 5.2 1.5 5.9 4.8 8.3 6.7 6.3 7.6 8.9 8.9 8.6 1.4 4.0 9.7 9.7 6.6 0.1 5.8 1.5 7.3 7.3 7.1 5.1 0.2 7.5 6.2 1.1 5.9 0.1 3.9 0.7 10.9 0.8 1.2 9.8 12.0 13.7 5.9 14.1 6.7 6.3 0.1 1.7 7.7 4.8 3.6 2.5 7.8 2.6 2.6 3.8 3.1 1.2 16.0 2.3 20.4 9.0 7.5 3.5 5.4 7.2 7.6 1.1 5.8 7.0 2.6 12.7 6.9 2.8 3.1 0.8 13.4 0.2 4.7 0.0 0.2 0.0 0.2 0.6 0.0 0.1 0.3 0.2 0.6 0.2 0.6 1.0 0.1 0.1 0.0 1.2 0.7 0.2 9.7 10.4 7.4 10.5 11.1 13.0 11.3 14.7 10.9 9.9 13.5 8.3 3.0 9.6 10.9 4.6 0.4 1.5 5.5 21.3 3.4 5.4 7.9 7.5 5.5 5.7 21.3 12.9 16.7 12.2 0.0 2.0 23.5 15.1 453.5 88.6 5.8 3.3 4.9 1.7 8.1 9.3 3.4 6.4 6.1 7.7 0.0 4.8 2.2 2.3 4.2 5.0 6.9 2.3 32.6 0.8 1.2 66.8 12.5 1.4 3.6 1.0 0.1 12.9 0.0 5.0 2.6 7.2 4.0 9.1 0.4 3.5 0.5 26.1 199.1 21.3 0.0 4.7 7.7 163.7 20.6 3.6 3.1 20.1 0.7 13.9 2.3 5.2 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446401-20455089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favorable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 5.7 6.3 6.1 3.8 6.2 6.1 7.0 6.4 7.3 6.8 6.8 7.6 3.8 6.4 8.5 6.0 6.1 6.6 8.1 6.0 6.3 5.8 11.1 6.2 9.3 6.4 6.1 5.3 5.6 7.4 5.2 6.7 6.4 4.9 7.0 4.1 5.3 8.3 10.5 4.7 6.2 5.6 6.5 8.4 6.4 2.4 6.3 9.9 7.6 9.9 10.1 8.2 4.9 6.9 10.3 17.2 5.6 16.2 9.9 6.6 17.6 8.0 11.3 21.1 20.1 21.5 12.3 21.1 10.3 11.0 9.0 8.6 17.9 17.6 14.1 16.8 19.1 14.8 12.2 32.1 7.4 24.3 19.7 5.3 5.2 26.1 14.0 4.6 14.3 18.8 14.0 12.1 17.6 21.0 25.0 11.8 9.1 31.5 31.8 35.3 10.3 12.4 12.8 11.7 21.3 4.2 15.4 16.0 11.9 3.3 9.7 23.7 6.1 8.7 21.2 11.3 10.7 3.4 18.0 31.7 5.0 36.1 11.0 9.3 29.2 38.5 18.8 27.9 17.4 28.7 19.7 17.2 44.5 38.1 15.9 17.4 13.8 20.9 23.3 16.9 19.2 24.6 6.1 6.2 6.4 7.3 6.0 6.3 6.4 6.1 6.4 6.5 6.3 6.9 27.1 35.3 34.9 16.3 46.0 11.5 20.9 26.2 14.2 37.8 24.0 25.1 17.2 15.7 29.1 23.9 37.5 66.3 31.8 22.5 35.2 24.7 3.1 19.2 18.3 24.1 26.9 19.6 23.0 29.8 47.0 23.4 28.1 16.3 25.9 24.6 25.7 19.3 65.8 10.1 24.1 24.2 22.4 30.7 32.8 3.0 19.3 34.2 21.4 7.5 28.4 31.0 32.0 16.6 17.0 20.0 30.6 21.4 26.2 10.9 42.2 39.7 25.5 51.5 13.1 24.6 23.9 7.8 16.9 22.0 11.5 46.1 26.8 37.3 31.6 17.4 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 20.1" "Cell type enriched" "Detected in some" 20 "Paneth cells: 627.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "HDLM-2: 10.1" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in many" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA024524: AB_2671592, HPA053090: AB_2682041" "unprognostic (1.62e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (3.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (9.04e-2)" "unprognostic (2.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.3 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.2 1.4 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 30.0 0.0 0.0 9.3 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 19.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 627.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 4.1 0.0 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 P3H3 "GRCB, HSU47926, LEPREL2" ENSG00000110811 "Prolyl 3-hydroxylase 3" Q8IVL6 12 6828407-6839847 "Enzymes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 19.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 47.2;Cone photoreceptor cells: 100.1;Horizontal cells: 43.7;Leydig cells: 49.7;Peritubular cells: 38.4;Rod photoreceptor cells: 28.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 39.6;hTERT-RPE1: 27.3;NTERA-2: 27.5;U-251 MG: 27.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043695 Approved Approved "Nucleoli,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 740000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Nucleoli "HPA043695: AB_10797146" "unprognostic (2.54e-1)" "unprognostic (6.66e-2)" "unprognostic (1.14e-1)" "unprognostic (3.34e-2)" "unprognostic (5.76e-2)" "unprognostic (6.55e-2)" "unprognostic (2.66e-1)" "unprognostic (2.92e-1)" "unprognostic (6.90e-2)" "unprognostic (1.44e-1)" "prognostic favorable (4.91e-4)" "unprognostic (1.29e-1)" "prognostic unfavorable (1.64e-4)" "unprognostic (2.58e-2)" "unprognostic (9.67e-2)" "unprognostic (2.27e-1)" "unprognostic (7.77e-3)" 3.5 2.6 1.2 1.5 0.7 0.3 3.9 3.7 2.7 11.9 5.6 5.4 0.8 19.2 0.5 1.6 9.9 1.7 4.5 1.1 1.2 2.0 0.6 3.7 0.3 1.3 0.2 12.4 2.9 4.5 15.4 1.3 0.3 6.0 0.3 4.1 6.5 3.7 0.8 3.0 2.8 3.8 0.2 1.3 3.8 1.2 0.9 0.1 4.3 0.3 0.3 7.8 6.4 0.5 0.0 1.6 7.1 14.0 8.4 10.2 0.3 39.6 22.4 12.2 13.5 0.6 0.0 0.0 0.5 14.9 0.5 0.0 4.4 0.4 2.7 0.1 18.8 1.0 4.2 1.9 5.9 1.0 0.0 11.1 0.4 6.0 3.3 27.3 13.1 1.2 3.7 0.0 5.7 0.0 0.1 0.4 27.5 0.0 1.1 0.0 6.9 0.2 0.6 0.0 2.8 10.5 0.1 0.0 4.8 3.4 0.2 0.2 23.2 12.0 17.5 18.6 27.7 0.1 0.3 0.3 10.2 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.7 3.7 2.7 1.1 1.2 1.3 0.2 0.3 0.2 0.9 0.5 2.3 0.0 0.0 3.3 0.5 0.0 4.9 0.0 2.2 47.2 5.3 5.5 11.1 1.5 1.8 5.5 100.1 0.5 0.1 0.1 1.9 1.4 0.9 0.9 19.6 3.9 1.2 0.0 13.1 2.7 0.5 24.1 2.0 0.4 0.0 0.8 7.9 0.0 1.4 43.7 13.7 2.7 0.0 0.0 0.0 2.2 49.7 0.5 0.0 2.8 1.1 5.3 0.0 5.5 1.3 1.3 0.1 38.4 3.1 5.1 0.4 0.4 1.5 28.8 6.6 7.8 11.9 0.7 0.8 0.8 0.0 1.0 0.9 3.2 0.6 1.5 PACSIN2 SDPII ENSG00000100266 "Protein kinase C and casein kinase substrate in neurons 2" Q9UNF0 22 42835412-43015149 "Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 95.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049854, HPA056520" Enhanced Supported "Nuclear speckles,Vesicles,Plasma membrane,Cytosol" NA NA 2400000 "Cluster 52: Eosinophils - Transcription" "Cluster 25: Pancreas - Digestion" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear speckles, Vesicles, Cytosol" "Plasma membrane" "HPA049854: AB_2680915, HPA056520: AB_2683163" "unprognostic (5.62e-3)" "unprognostic (1.22e-1)" "unprognostic (1.71e-2)" "unprognostic (1.64e-3)" "unprognostic (1.63e-2)" "unprognostic (3.96e-1)" "prognostic unfavorable (7.33e-4)" "unprognostic (4.48e-2)" "unprognostic (3.40e-2)" "unprognostic (2.82e-3)" "unprognostic (3.09e-2)" "unprognostic (1.00e-1)" "prognostic favorable (1.09e-13)" "unprognostic (2.87e-1)" "unprognostic (1.11e-1)" "unprognostic (6.20e-2)" "unprognostic (2.95e-1)" 40.8 74.3 25.7 37.1 29.1 29.3 40.7 34.2 27.3 37.5 32.3 61.7 40.8 39.1 21.2 34.1 35.3 45.3 55.7 27.7 39.2 47.1 41.1 50.9 34.2 40.5 36.8 31.4 162.4 29.4 39.9 34.2 40.8 47.0 41.6 28.2 43.5 27.4 49.8 39.5 38.1 30.4 30.7 35.9 51.5 19.5 32.5 28.7 43.9 42.4 26.4 36.5 34.5 31.1 76.3 78.3 64.6 41.5 32.6 34.6 52.9 67.8 40.7 59.9 49.7 82.1 43.8 35.2 56.1 50.6 40.8 52.8 42.5 72.1 39.3 36.1 42.4 56.8 39.4 117.8 46.1 40.5 118.1 33.4 69.8 79.1 34.3 48.7 49.9 32.1 49.9 24.9 52.2 49.7 43.1 63.3 35.6 110.4 32.7 52.3 96.5 23.8 68.9 44.4 41.9 18.7 81.1 55.2 155.8 41.5 40.1 53.1 74.3 44.5 56.4 50.0 40.5 18.4 27.2 38.4 42.7 35.4 99.1 26.1 18.5 47.4 6.8 32.2 7.3 11.3 7.8 5.8 21.5 11.6 7.6 5.8 95.7 16.8 33.9 7.9 12.1 14.1 25.7 29.1 34.2 27.3 27.7 39.2 40.5 36.8 40.8 30.7 32.5 31.1 31.7 70.5 60.6 20.2 20.6 23.2 43.4 23.9 21.1 15.7 37.4 31.1 26.3 24.3 37.2 46.0 39.6 34.4 19.9 142.6 45.0 80.2 3.6 51.6 31.3 28.6 24.7 12.6 22.7 65.4 29.6 20.9 36.7 57.4 71.0 14.7 16.1 22.3 42.7 6.7 41.0 49.5 30.5 38.5 50.0 6.2 21.8 44.9 83.6 54.4 51.3 8.4 7.2 29.1 19.5 70.9 62.3 23.3 13.1 50.6 32.0 55.0 30.7 24.9 92.1 23.5 82.9 22.6 27.6 22.5 16.9 48.2 19.1 13.8 42.2 30.3 PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Extravillous trophoblasts: 60.6;Muller glia cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" 14.4 66.5 19.6 4.5 28.2 0.4 18.4 24.5 20.9 33.3 18.8 50.2 4.7 33.5 11.4 52.6 29.1 7.2 161.8 18.0 19.4 14.8 43.6 15.9 2.0 33.8 27.5 23.2 33.1 11.0 6.2 16.1 32.1 35.2 2.7 4.5 40.8 20.6 480.9 41.4 11.3 21.2 25.0 4.5 33.5 4.5 25.4 2.0 24.5 279.4 5.2 21.5 31.8 39.0 56.4 27.1 12.5 51.5 10.3 10.2 59.8 19.4 24.6 33.9 19.1 40.8 7.3 0.3 5.9 9.2 23.0 90.0 23.7 40.2 13.0 8.7 44.8 8.4 105.5 91.7 19.9 2.0 8.4 28.2 52.3 17.9 28.3 27.2 15.3 15.2 18.4 0.7 13.9 106.7 0.7 40.8 15.5 43.7 58.7 33.1 48.0 9.0 14.3 49.3 0.3 42.6 28.2 17.9 24.6 24.6 127.3 6.9 6.9 57.6 62.5 7.5 47.1 10.1 4.4 5.3 18.6 19.2 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.6 28.2 24.5 20.9 18.0 19.4 33.8 27.5 32.1 25.0 25.4 39.0 6.1 0.0 8.1 4.9 0.3 35.9 29.1 25.1 30.7 0.7 32.2 24.3 112.0 38.6 18.1 5.5 0.0 31.0 0.6 0.2 9.8 37.7 0.0 3.1 8.4 7.8 0.0 2.7 0.8 15.5 60.6 12.6 9.7 6.2 0.0 3.0 8.6 33.1 6.0 0.0 1.1 0.2 14.2 1.6 4.6 0.4 16.1 1.0 17.8 2.8 0.0 63.6 0.0 0.0 9.5 41.0 0.0 12.4 2.6 56.8 1.5 24.3 5.0 3.2 32.9 18.5 25.4 0.2 7.5 39.7 29.8 18.3 0.7 4.8 1.4 29.8 PAFAH1B2 ENSG00000168092 "Platelet activating factor acetylhydrolase 1b catalytic subunit 2" P68402 11 117144284-117176894 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051836 Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA 250000 "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 1: K-562 - Erythropoiesis" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoli, Plasma membrane" "HPA051836: AB_2681630" "unprognostic (1.08e-2)" "unprognostic (3.14e-2)" "unprognostic (2.07e-2)" "unprognostic (3.88e-2)" "unprognostic (9.94e-2)" "unprognostic (1.21e-3)" "prognostic unfavorable (9.44e-4)" "prognostic unfavorable (3.07e-4)" "unprognostic (1.01e-1)" "prognostic favorable (4.25e-4)" "prognostic unfavorable (7.79e-5)" "unprognostic (8.18e-2)" "unprognostic (1.11e-2)" "unprognostic (9.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.46e-1)" "unprognostic (1.34e-1)" 23.1 34.3 35.1 21.2 42.2 41.2 20.6 43.9 45.0 20.8 28.4 21.7 22.4 23.8 22.7 23.9 20.9 19.9 28.2 33.9 45.4 25.3 23.8 21.7 20.7 47.6 45.0 23.3 20.3 21.9 24.5 25.4 51.0 22.3 20.0 23.2 17.4 16.1 15.7 22.0 19.4 20.4 48.7 20.4 23.0 30.0 43.6 21.5 31.9 20.3 22.2 26.9 20.9 51.6 43.4 48.5 54.9 79.7 60.1 41.7 42.6 71.0 61.7 38.8 35.2 89.2 92.9 46.6 99.4 85.8 38.7 67.7 80.6 92.0 50.9 41.8 31.1 120.0 41.3 57.9 53.8 42.1 44.0 46.6 71.7 77.4 96.7 42.4 64.8 25.6 65.0 34.6 60.3 27.7 40.8 61.7 50.4 60.0 37.8 44.9 62.2 51.2 59.8 66.7 60.9 80.5 82.2 61.6 28.1 46.6 68.4 35.6 103.8 70.4 46.3 34.8 51.4 10.8 17.9 61.5 28.3 78.8 60.4 63.4 51.4 48.6 39.0 58.7 46.4 43.8 44.7 41.0 37.4 41.2 45.8 49.2 63.7 33.1 66.3 27.4 35.1 53.1 35.1 42.2 43.9 45.0 33.9 45.4 47.6 45.0 51.0 48.7 43.6 51.6 48.5 28.9 34.8 17.9 41.4 122.4 44.5 45.9 54.7 38.6 55.4 32.1 37.6 58.6 32.8 66.2 47.9 40.4 44.4 48.0 46.9 61.3 13.1 63.6 54.8 64.8 82.6 39.4 29.2 39.5 86.7 40.8 33.6 78.4 19.0 36.8 79.6 47.0 43.0 47.1 32.5 41.8 36.7 65.4 175.9 13.7 45.4 52.1 49.8 20.6 59.3 36.2 21.6 13.0 61.2 99.0 50.5 34.3 28.9 67.0 33.7 54.8 32.9 38.3 13.1 42.8 40.0 54.7 84.7 53.2 115.9 54.6 41.6 35.2 45.4 50.6 PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 169.6;granulocytes: 124.5;Melanocytes: 140.5;Microglial cells: 166.8;Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 35.4;HMC-1: 45.5;SK-MEL-30: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" 3.9 3.1 3.4 9.0 3.5 12.3 2.0 14.8 4.0 1.8 4.3 9.2 7.6 1.9 2.2 1.6 1.8 7.1 4.7 2.8 3.7 1.7 4.7 14.9 14.5 4.5 4.5 1.2 14.9 0.9 2.0 16.0 4.9 2.6 8.7 5.0 3.7 2.1 1.3 4.3 9.0 3.0 4.9 9.1 4.4 0.7 5.2 10.4 1.8 2.1 14.0 4.8 2.6 5.6 0.1 0.1 4.8 0.2 8.9 8.5 0.1 2.0 15.5 1.0 1.9 0.3 0.1 35.4 0.2 0.5 7.6 1.5 0.1 1.8 0.9 0.9 4.5 20.8 0.3 0.0 9.1 3.4 45.5 4.1 1.2 8.9 8.2 0.9 0.0 6.2 0.2 0.1 14.8 0.3 12.6 0.3 0.4 8.1 1.4 9.5 2.4 0.1 1.6 7.6 1.0 1.7 0.0 0.3 36.1 0.8 1.2 3.5 0.3 1.1 0.6 0.0 1.2 5.7 1.6 12.3 9.7 11.7 8.5 13.1 1.4 2.0 2.5 6.4 6.1 2.0 6.2 4.4 1.9 1.6 4.9 3.8 2.3 1.7 14.6 4.1 7.2 2.7 3.4 3.5 14.8 4.0 2.8 3.7 4.5 4.5 4.9 4.9 5.2 5.6 6.2 0.0 12.4 40.8 37.0 31.5 3.9 5.2 0.6 39.7 2.2 2.2 15.4 10.0 14.0 3.7 0.0 0.8 39.0 169.6 0.0 4.0 3.5 0.6 4.4 10.9 3.6 3.8 57.5 6.5 26.2 24.3 8.2 1.1 124.5 97.0 12.5 10.3 27.1 63.9 60.0 23.2 6.1 73.6 26.2 2.1 2.5 79.1 140.5 166.8 40.8 34.9 19.6 82.4 75.3 2.0 62.1 7.9 38.4 7.7 109.3 0.4 0.8 3.2 124.9 32.3 37.1 0.2 3.0 3.8 22.6 2.3 78.1 11.8 27.4 13.7 PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 60000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "HPA073653: AB_2732234, HPA076187: AB_2686784" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (5.37e-2)" "unprognostic (2.65e-2)" "unprognostic (1.62e-2)" "unprognostic (4.74e-2)" "unprognostic (1.13e-3)" "unprognostic (2.98e-1)" "unprognostic (3.17e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (3.54e-1)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" 69.5 54.3 47.8 36.6 50.8 56.6 67.4 52.0 64.2 65.1 52.0 57.1 43.3 61.6 57.3 52.0 51.2 53.3 92.5 51.2 52.0 78.0 90.9 50.3 39.4 49.5 49.5 53.7 54.8 74.3 29.3 68.1 50.8 69.1 54.8 95.2 51.3 68.5 155.3 31.1 40.2 65.3 54.3 34.2 46.9 83.6 49.0 47.6 73.6 122.9 45.3 70.1 39.9 56.5 94.5 82.2 158.0 153.7 161.8 127.1 129.1 81.2 180.0 151.5 130.9 77.2 112.8 62.5 136.9 115.5 227.3 60.4 249.3 98.0 153.5 52.2 96.7 49.2 157.1 122.6 142.3 74.2 74.3 135.8 186.1 102.5 191.7 153.1 146.8 45.9 115.9 82.1 153.0 101.7 82.4 101.8 78.5 89.4 104.8 63.8 119.2 88.1 188.8 114.3 89.4 135.3 260.3 99.2 190.0 144.0 141.4 106.3 82.4 136.6 112.5 68.8 103.7 61.7 112.6 94.3 79.7 113.1 120.4 40.4 24.1 46.2 18.9 20.7 25.2 26.4 23.2 26.2 23.7 26.7 28.9 23.2 8.6 24.9 22.5 66.8 23.0 22.1 47.8 50.8 52.0 64.2 51.2 52.0 49.5 49.5 50.8 54.3 49.0 56.5 66.4 32.1 52.2 15.0 39.4 73.3 74.0 78.5 52.3 48.8 78.8 53.1 122.4 78.6 52.7 44.1 20.9 76.3 66.0 33.1 158.5 120.3 182.6 73.8 56.4 71.2 44.9 54.9 30.0 91.6 89.2 64.2 39.3 55.9 24.6 47.4 50.0 49.2 59.4 35.3 25.3 52.1 103.7 40.9 39.7 58.0 76.4 42.0 83.6 20.6 53.8 86.6 24.7 26.7 35.1 116.4 43.8 66.5 43.3 106.4 45.1 148.8 40.9 67.7 26.3 70.2 71.4 171.2 76.6 56.0 66.3 68.1 35.1 49.7 47.7 84.3 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "classical monocyte: 182.2;eosinophil: 292.7;intermediate monocyte: 177.7;myeloid DC: 264.3;neutrophil: 431.8;non-classical monocyte: 202.6" "Group enriched" "Detected in all" 11 "dendritic cells: 264.3;granulocytes: 431.8;monocytes: 202.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 560000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 12.7 13.4 32.4 33.9 44.5 59.0 18.2 13.9 57.7 21.1 0.0 43.2 43.1 20.9 29.8 21.4 21.9 30.9 9.4 58.3 8.0 26.1 14.5 16.8 20.4 19.2 12.2 21.1 17.5 20.5 20.7 14.7 19.4 19.1 46.5 25.1 19.9 19.7 87.0 16.2 45.7 27.0 0.9 29.3 41.2 25.7 17.1 29.1 40.6 18.8 23.1 27.7 20.7 30.0 39.9 26.7 56.7 25.5 22.8 37.6 45.9 44.6 32.1 42.0 48.7 38.7 52.8 36.3 16.0 39.4 54.4 20.2 40.2 47.8 65.5 41.4 32.6 38.2 17.6 2.3 15.3 64.3 53.5 28.2 28.8 49.2 73.1 36.6 10.1 41.3 25.5 61.2 77.6 2.9 42.3 30.2 84.5 166.2 22.5 62.6 72.3 1.4 10.6 32.9 24.6 23.9 23.6 9.7 19.5 55.0 45.4 29.0 0.9 27.3 47.5 148.9 37.9 165.7 92.4 23.4 23.0 42.5 30.6 2.5 182.2 292.7 11.2 177.7 9.4 16.8 8.4 10.7 264.3 12.9 7.4 14.5 431.8 28.4 202.6 22.9 7.3 92.3 32.4 44.5 13.9 57.7 58.3 8.0 19.2 12.2 19.4 0.9 17.1 30.0 3.1 3.2 20.5 24.2 23.9 11.9 33.3 28.2 23.9 51.6 25.1 19.7 6.2 35.8 30.8 25.8 8.4 25.4 10.2 78.6 45.0 32.4 38.8 37.3 13.5 3.2 37.8 30.5 219.1 56.3 53.5 24.0 45.9 39.7 132.2 35.2 3.6 11.4 49.8 1.7 118.5 50.8 28.5 59.6 152.9 28.3 14.3 80.0 30.2 54.4 121.7 14.9 10.3 53.3 70.7 50.9 57.9 13.2 28.6 28.7 47.9 55.7 39.0 6.4 13.1 13.8 25.2 50.4 53.8 23.6 10.4 95.0 19.3 10.3 52.8 33.2 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PAK6 PAK5 ENSG00000137843 "P21 (RAC1) activated kinase 6" Q9NQU5 15 40217428-40277487 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 25.6;skin 1: 28.2" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 52.7;NK-cells: 16.5;Suprabasal keratinocytes: 19.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 26.5;HaCaT: 32.2;hTCEpi: 19.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA031124 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli fibrillar center" "Cell Junctions" "HPA031124: AB_10601044" "unprognostic (1.85e-3)" "unprognostic (2.15e-1)" "unprognostic (3.33e-3)" "unprognostic (7.79e-3)" "unprognostic (7.08e-3)" "unprognostic (9.57e-2)" "unprognostic (2.71e-1)" "unprognostic (7.73e-2)" "unprognostic (1.34e-2)" "unprognostic (7.13e-3)" "unprognostic (4.04e-2)" "unprognostic (8.87e-3)" "unprognostic (1.72e-1)" "unprognostic (1.79e-1)" "unprognostic (7.37e-3)" "unprognostic (3.34e-2)" 0.2 8.2 11.6 0.4 15.9 0.9 2.1 8.5 16.6 4.5 0.0 1.3 1.5 0.9 1.0 25.6 4.3 1.1 8.3 17.6 3.0 4.7 0.3 2.5 0.9 1.4 1.1 0.6 8.0 8.0 12.1 7.6 1.9 4.4 1.1 0.8 6.1 3.8 4.5 28.2 1.5 0.3 1.8 0.9 3.9 17.7 3.0 0.5 7.5 1.3 1.9 3.5 9.4 5.4 3.9 0.0 0.2 0.0 0.0 0.0 6.0 0.0 0.2 0.7 0.7 26.5 2.9 0.1 3.6 0.0 1.3 32.2 4.5 6.9 0.3 0.2 1.0 0.0 3.0 0.2 0.0 0.1 0.3 0.0 19.4 0.3 4.5 0.2 0.0 5.5 1.8 0.3 0.0 4.5 0.0 0.5 0.5 3.9 2.9 0.2 0.2 2.9 1.5 8.4 7.3 2.0 2.6 10.9 0.3 1.7 1.7 10.3 0.0 0.3 0.6 0.0 0.3 0.1 0.3 0.1 0.7 0.6 0.2 1.2 0.1 1.2 2.3 0.1 0.8 0.6 0.1 1.9 0.3 0.1 0.1 0.4 0.5 0.9 0.1 0.1 0.0 0.6 11.6 15.9 8.5 16.6 17.6 3.0 1.4 1.1 1.9 1.8 3.0 5.4 0.0 0.0 4.2 0.7 0.3 9.8 9.6 4.8 8.6 3.5 2.8 2.9 0.0 4.3 5.4 5.5 0.0 52.7 2.1 0.3 13.7 4.4 8.6 3.3 0.4 0.3 4.9 0.0 8.9 4.3 3.0 0.7 0.5 5.1 0.0 0.7 0.0 0.0 4.1 0.0 7.3 1.1 2.0 0.6 0.9 5.8 1.8 0.3 1.8 1.0 0.0 1.3 16.5 0.5 0.3 2.5 1.0 1.9 0.1 5.2 0.2 0.2 3.9 0.2 0.0 0.3 0.4 1.9 3.3 13.9 19.0 9.0 1.0 0.8 2.0 11.3 PALLD "CGI-151, KIAA0992, SIH002" ENSG00000129116 "Palladin, cytoskeletal associated protein" Q8WX93 4 168497052-168928457 "Disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 527.9;Cardiomyocytes: 591.7;Peritubular cells: 399.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 304.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035905, CAB070159" Enhanced Supported "Plasma membrane,Actin filaments,Mitochondria,Cytosol" No No 27000 "Cluster 10: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Actin filaments" "Plasma membrane, Mitochondria, Cytosol" "CAB070159: AB_1726016, HPA035905: AB_2674854" "unprognostic (3.59e-2)" "unprognostic (3.99e-1)" "unprognostic (2.55e-2)" "unprognostic (5.03e-3)" "unprognostic (2.51e-1)" "unprognostic (7.03e-2)" "unprognostic (2.60e-1)" "unprognostic (2.40e-2)" "unprognostic (3.57e-2)" "unprognostic (4.21e-2)" "unprognostic (2.38e-1)" "unprognostic (3.86e-1)" "unprognostic (8.54e-2)" "unprognostic (1.39e-2)" "unprognostic (1.36e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (3.28e-4)" 65.0 35.5 31.7 49.7 27.3 0.9 43.6 11.1 19.9 146.1 0.0 303.3 29.0 301.5 21.9 122.6 118.4 71.0 180.4 27.9 36.2 42.1 12.4 71.7 16.9 29.8 25.9 62.1 13.2 55.6 11.3 62.1 25.1 137.0 74.9 12.8 40.8 205.7 127.7 34.7 64.1 303.1 21.4 60.5 94.8 35.1 24.7 23.3 38.7 47.3 16.6 280.2 85.3 22.7 82.1 39.6 87.9 53.4 77.2 83.9 123.6 53.7 137.6 47.2 66.7 1.1 4.6 36.6 14.4 23.7 29.0 17.0 54.1 138.8 60.5 73.9 16.6 0.8 112.5 10.4 135.5 0.4 1.0 132.8 84.4 85.5 125.4 115.0 20.8 19.7 0.1 0.5 304.5 3.8 23.8 1.4 24.9 20.8 24.1 8.3 81.4 0.8 5.3 16.4 9.0 46.4 102.8 8.1 7.3 151.2 48.6 0.5 64.4 50.3 192.1 20.7 90.1 47.8 0.7 1.7 41.6 1.0 14.2 13.7 3.1 0.0 4.6 1.8 0.2 0.1 0.5 2.4 2.1 0.1 0.6 1.6 0.7 0.6 1.2 0.2 0.8 1.8 31.7 27.3 11.1 19.9 27.9 36.2 29.8 25.9 25.1 21.4 24.7 22.7 22.7 32.1 9.4 167.8 1.5 93.6 527.9 56.8 76.8 6.0 46.0 107.9 591.7 20.0 58.7 44.1 18.8 52.1 8.1 20.9 1.9 27.6 133.1 52.8 181.2 27.7 44.8 0.8 27.8 51.3 115.6 130.5 59.7 51.0 52.6 21.0 47.8 11.2 24.5 26.9 108.4 30.7 18.3 28.9 23.8 146.4 130.1 36.7 23.2 16.9 52.9 55.1 17.5 182.4 6.5 83.0 18.6 399.4 2.6 167.6 9.8 23.4 85.2 4.0 177.5 115.4 227.8 81.0 7.6 34.1 49.3 22.3 9.2 13.4 29.3 113.0 PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 257.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.2;Distal tubular cells: 52.8;Hepatic stellate cells: 63.1;Leydig cells: 48.4;Muller glia cells: 92.8;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;EFO-21: 20.7;REH: 34.3;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA041713: AB_10794305, HPA049578: AB_2680822" "unprognostic (9.08e-3)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (3.53e-3)" "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (8.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.36e-2)" "prognostic favorable (9.81e-4)" "unprognostic (2.74e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (6.00e-2)" 89.0 23.1 158.4 2.0 140.7 0.7 66.0 86.1 257.8 60.3 54.5 54.4 7.4 43.3 3.3 14.4 47.0 2.8 41.1 165.1 97.0 52.7 7.3 30.0 0.6 106.4 103.6 65.7 5.8 1.2 62.5 6.6 96.9 42.6 0.6 4.6 12.9 8.3 9.6 33.4 20.8 2.4 95.0 23.4 18.0 19.6 112.1 0.6 21.0 1.7 0.2 29.4 41.8 110.5 0.0 7.6 14.6 16.6 0.6 0.2 2.2 0.9 0.0 1.0 0.2 1.9 0.1 0.0 20.7 0.0 0.0 2.7 8.0 0.0 0.4 0.0 14.1 0.0 4.3 9.3 9.4 0.0 0.3 3.0 0.0 0.9 0.0 0.4 0.4 1.6 4.6 0.1 1.1 15.9 1.1 9.4 5.9 1.0 3.2 34.3 0.0 0.2 0.6 0.0 1.7 28.0 7.5 0.1 0.2 4.6 1.8 4.5 0.0 0.0 13.4 16.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 158.4 140.7 86.1 257.8 165.1 97.0 106.4 103.6 96.9 95.0 112.1 110.5 27.2 0.0 1.7 85.2 2.7 7.1 7.2 6.3 1.8 11.4 5.7 5.3 5.8 1.5 4.9 5.5 12.5 0.9 0.2 1.3 52.8 1.4 1.4 3.8 27.0 25.6 0.0 1.3 26.9 0.2 7.2 37.6 1.1 5.9 0.0 1.4 63.1 0.4 1.0 25.2 15.1 0.1 12.2 2.4 5.4 6.6 48.4 1.1 17.8 10.3 0.1 92.8 0.0 16.6 9.8 0.2 1.4 45.1 0.1 10.1 7.2 57.9 0.5 5.7 0.0 2.3 14.1 0.8 7.3 1.1 7.0 1.9 1.1 0.1 0.4 7.2 PALM2AKAP2 PALM2-AKAP2 ENSG00000157654 "PALM2 and AKAP2 fusion" "Q8IXS6, Q9Y2D5" 9 109498325-110172512 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 10.6;naive B-cell: 10.3" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA058905, HPA074153, HPA076866" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA058905: AB_2683851, HPA074153: AB_2686669, HPA076866: " "unprognostic (7.12e-2)" "unprognostic (1.64e-6)" "unprognostic (7.90e-2)" "unprognostic (3.67e-2)" "unprognostic (2.45e-1)" "unprognostic (3.19e-1)" "unprognostic (9.91e-2)" "unprognostic (1.37e-1)" "unprognostic (1.75e-1)" "unprognostic (8.37e-3)" "unprognostic (2.40e-2)" "unprognostic (2.77e-1)" "unprognostic (1.19e-1)" "unprognostic (2.05e-3)" "unprognostic (7.77e-2)" "unprognostic (1.98e-4)" "unprognostic (3.36e-5)" 97.0 13.5 21.8 37.3 21.1 9.9 17.5 6.9 22.7 28.5 0.0 17.4 14.8 28.8 8.5 26.5 14.7 37.4 93.8 15.7 18.5 30.8 38.2 69.1 32.2 18.1 26.6 9.3 13.1 14.0 0.1 97.9 20.3 14.9 18.1 3.3 38.0 25.1 17.0 10.1 13.3 48.5 10.5 38.4 18.5 4.6 38.8 45.4 25.6 24.3 31.7 43.0 0.4 26.3 20.6 7.7 112.5 0.1 110.8 93.0 33.4 116.0 141.3 101.6 93.4 134.6 17.9 92.1 30.6 129.6 146.2 28.9 9.5 98.8 185.4 68.9 12.5 9.2 30.4 11.0 75.9 12.4 256.2 109.8 24.7 183.3 280.4 62.5 150.9 14.5 0.3 76.2 204.7 1.2 61.9 31.1 47.2 9.1 62.6 5.5 98.2 25.3 72.4 2.8 25.2 1.5 10.3 9.5 26.4 87.8 4.1 22.2 240.0 94.0 77.9 137.5 108.8 52.5 89.1 52.5 81.4 51.3 73.9 2.9 0.1 1.3 1.0 0.2 0.2 10.6 1.2 1.4 1.2 10.3 0.7 0.8 0.5 2.2 0.0 2.4 3.9 1.4 21.8 21.1 6.9 22.7 15.7 18.5 18.1 26.6 20.3 10.5 38.8 26.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PALM3 ENSG00000187867 "Paralemmin 3" A6NDB9 19 14053363-14062076 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 46.9;liver: 55.7;stomach 1: 30.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Alveolar cells type 2: 40.9;Cholangiocytes: 22.8;Collecting duct cells: 38.6;Exocrine glandular cells: 27.9;Hepatocytes: 40.5;Spermatogonia: 18.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AN3-CA: 17.6;CACO-2: 20.2;GAMG: 5.5;HAP1: 15.8;NTERA-2: 10.3" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA052794, HPA056119" Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA052794: AB_2681952, HPA056119: AB_2683042" "unprognostic (3.67e-2)" "unprognostic (9.08e-2)" "unprognostic (4.72e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.14e-2)" "unprognostic (1.47e-1)" "unprognostic (4.66e-2)" "unprognostic (7.62e-2)" "unprognostic (1.97e-1)" "unprognostic (3.91e-1)" "unprognostic (3.93e-2)" "unprognostic (3.88e-2)" "unprognostic (2.09e-2)" "unprognostic (1.06e-1)" "unprognostic (5.68e-2)" "unprognostic (1.10e-2)" "unprognostic (1.72e-3)" 0.1 0.2 1.3 0.1 1.4 0.0 0.6 1.3 1.5 2.0 1.0 0.8 1.6 1.0 6.7 0.3 1.8 1.0 0.4 1.3 1.8 46.9 55.7 4.3 0.0 2.9 1.7 0.2 24.5 6.5 0.4 0.4 2.6 4.0 0.2 0.5 3.7 4.5 0.1 0.5 1.1 0.0 1.7 0.1 30.5 15.2 1.8 0.0 12.7 0.0 0.0 4.7 1.6 1.7 1.4 1.3 2.9 17.6 0.3 0.0 3.3 0.3 0.0 0.7 0.5 20.2 0.3 0.0 0.2 0.4 5.5 0.0 15.8 0.0 0.3 0.0 0.9 0.1 0.5 2.3 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.5 0.0 0.0 3.4 0.0 0.0 3.2 0.2 0.0 10.3 1.6 0.8 0.0 0.0 0.0 0.0 1.7 1.9 2.3 0.1 0.0 0.0 3.2 1.3 0.0 0.1 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.4 1.3 1.5 1.3 1.8 2.9 1.7 2.6 1.7 1.8 1.7 0.1 57.7 40.9 0.3 0.5 0.0 0.6 0.1 0.0 0.7 1.0 1.4 0.3 22.8 10.1 38.6 0.0 0.3 0.0 0.7 1.9 9.4 0.0 3.2 1.0 0.2 1.2 0.0 0.3 27.9 3.1 1.7 7.1 6.3 1.3 0.1 1.8 40.5 0.1 0.0 0.5 3.0 0.0 1.3 0.3 0.5 0.9 0.2 1.8 0.0 1.0 0.8 0.0 0.0 0.1 5.5 1.3 2.6 0.0 1.0 3.2 9.5 2.1 0.6 0.0 0.1 0.2 0.0 18.8 0.0 0.0 2.2 0.3 0.0 1.0 1.0 PALMD "C1orf11, FLJ20271, PALML" ENSG00000099260 Palmdelphin Q9NP74 1 99646113-99694541 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 130.8" "Cell type enhanced" "Detected in many" "Adipocytes: 537.2;Cardiomyocytes: 157.6;Endothelial cells: 219.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 155.2;LHCN-M2: 49.5;TIME: 220.5;U-87 MG: 92.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017959, HPA030549" Supported Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Focal adhesion sites" "HPA017959: AB_1854949, HPA030549: AB_2673518" "unprognostic (1.48e-2)" "unprognostic (1.15e-2)" "unprognostic (2.05e-2)" "prognostic favorable (9.42e-4)" "unprognostic (7.67e-2)" "prognostic favorable (5.90e-5)" "unprognostic (1.54e-2)" "unprognostic (2.10e-1)" "unprognostic (3.93e-2)" "unprognostic (1.64e-1)" "unprognostic (8.32e-2)" "unprognostic (6.18e-2)" "unprognostic (5.19e-2)" "unprognostic (1.63e-2)" "unprognostic (1.88e-1)" "unprognostic (2.70e-1)" "unprognostic (8.08e-2)" 130.8 43.0 14.6 7.1 11.7 0.0 77.6 10.5 15.3 27.4 45.8 9.5 3.4 33.0 6.1 38.2 22.8 14.6 91.2 13.7 12.7 11.0 57.1 28.4 3.9 12.0 11.8 18.8 4.9 9.2 10.5 43.2 11.5 18.0 6.5 7.5 71.0 7.9 112.6 48.9 8.6 31.4 11.1 6.3 6.1 11.0 14.1 8.0 7.2 66.2 8.6 14.5 15.9 10.4 0.0 0.3 0.4 0.2 7.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 39.2 2.5 0.6 10.8 0.0 0.5 0.1 0.1 0.1 0.0 18.6 26.4 0.0 0.0 0.1 3.9 2.0 0.0 0.0 4.3 155.2 0.0 22.7 0.0 49.5 0.6 0.0 0.0 0.0 1.6 6.8 0.0 38.2 0.1 0.0 8.0 0.9 0.5 0.0 9.9 0.0 1.0 2.3 0.0 220.5 0.0 0.4 16.8 0.0 0.0 0.0 0.1 92.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.6 11.7 10.5 15.3 13.7 12.7 12.0 11.8 11.5 11.1 14.1 10.4 537.2 6.4 5.6 0.3 0.5 38.5 11.4 49.6 22.2 2.0 20.0 31.8 157.6 32.9 35.9 3.7 0.0 0.4 1.6 0.1 5.9 8.1 74.9 78.7 71.9 219.4 1.8 2.7 1.4 0.2 0.3 19.2 2.0 17.7 1.3 0.0 96.0 57.3 0.6 3.3 1.8 0.0 14.2 2.2 5.5 12.2 9.3 1.7 24.9 73.1 0.0 55.0 0.0 0.5 0.2 4.1 0.0 24.0 0.0 5.9 0.0 0.4 111.5 3.3 0.0 91.3 12.7 0.5 0.6 27.5 46.5 0.3 1.4 110.1 0.1 3.3 PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA016930: AB_1854954" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.09e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-3)" 11.4 7.2 5.1 12.1 5.2 4.1 6.4 1.2 5.5 7.9 2.7 8.4 5.4 8.5 5.2 7.9 5.2 11.5 9.9 5.0 7.1 6.9 16.8 10.2 6.4 2.1 2.9 7.1 7.4 4.4 4.7 9.7 3.3 7.7 7.2 3.1 6.0 7.0 20.8 8.3 5.8 12.8 2.8 5.8 7.4 9.9 4.9 8.1 8.7 10.8 7.0 21.9 6.5 2.7 24.6 10.2 26.2 16.0 23.9 32.3 17.1 29.8 63.0 25.1 30.7 26.2 37.6 7.8 27.3 30.5 46.1 50.5 20.9 49.2 25.2 33.6 10.9 36.0 10.2 13.5 23.1 18.7 31.0 25.7 33.9 32.8 29.2 16.1 21.2 20.1 23.8 27.5 28.3 7.8 31.3 4.4 21.0 19.7 18.2 36.7 35.0 9.7 16.3 24.0 11.0 31.9 20.9 11.9 14.4 13.3 25.2 9.5 15.4 49.5 25.5 16.4 29.9 4.5 18.2 12.6 20.6 19.0 32.2 3.2 4.0 0.3 2.1 2.2 2.4 1.3 1.7 2.3 2.7 1.2 1.6 1.7 0.2 2.6 1.4 0.4 2.9 3.2 5.1 5.2 1.2 5.5 5.0 7.1 2.1 2.9 3.3 2.8 4.9 2.7 3.8 0.0 8.7 4.6 6.6 102.0 12.3 14.9 13.6 1.3 4.5 2.0 4.7 4.3 4.7 1.8 0.0 12.8 5.3 4.7 0.0 15.7 5.3 9.1 13.0 6.8 2.4 5.2 8.9 18.2 32.4 17.5 7.1 13.9 9.5 4.0 2.2 8.1 20.5 0.0 15.4 4.1 0.0 3.1 21.6 3.9 4.4 11.5 17.8 8.4 3.7 1.1 1.0 9.5 5.8 26.1 3.4 3.8 7.4 10.2 2.6 2.1 6.2 1.1 0.0 16.9 10.6 1.7 8.2 8.3 72.2 23.8 6.6 10.1 4.2 12.7 PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.4;Excitatory neurons: 13.3;Hepatocytes: 10.7;Inhibitory neurons: 15.8;Muller glia cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 10.3;HDLM-2: 16.7;Hep G2: 19.6;MCF7: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA004624: , HPA039117: AB_10805354" "unprognostic (1.00e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-9)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.00e-1)" "unprognostic (4.08e-1)" 1.0 0.8 4.4 0.5 4.4 1.6 1.0 8.4 40.1 1.7 0.0 0.3 0.0 1.2 0.5 5.2 2.2 0.4 0.7 8.0 13.1 3.0 9.6 2.1 0.0 51.0 8.8 3.4 1.4 0.3 7.9 0.1 48.4 3.9 0.0 1.6 5.0 1.4 0.7 1.1 0.2 0.0 7.9 1.9 0.4 1.7 14.1 0.0 7.3 0.1 0.1 1.4 1.9 16.4 0.9 2.1 0.4 2.3 0.0 0.2 4.9 2.6 2.5 0.5 0.4 0.5 8.0 0.0 10.3 0.3 1.4 0.5 1.3 1.0 0.1 16.7 1.4 0.4 3.5 19.6 0.7 0.1 1.2 0.2 1.0 0.7 0.0 1.1 0.6 0.0 1.4 0.0 0.2 10.8 0.0 1.0 3.9 0.0 4.2 1.0 0.0 4.0 0.0 1.6 9.8 0.9 1.6 0.2 6.5 0.5 0.7 0.8 4.5 0.5 4.1 6.7 4.9 1.8 0.1 0.6 0.3 0.0 7.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 4.4 4.4 8.4 40.1 8.0 13.1 51.0 8.8 48.4 7.9 14.1 16.4 0.0 0.0 1.1 7.2 0.3 0.5 3.1 0.6 0.0 11.4 2.5 2.4 0.8 1.5 2.6 0.0 0.0 0.0 1.5 0.0 5.9 2.3 0.3 5.9 1.5 0.7 0.0 0.4 13.3 2.8 0.2 0.8 0.0 7.0 0.0 2.1 0.0 10.7 0.1 0.0 15.8 0.0 0.0 0.9 1.5 0.2 0.0 1.1 0.0 1.9 1.8 29.7 0.0 6.6 1.2 1.8 0.0 1.2 0.5 6.0 0.0 3.0 3.0 3.6 0.0 0.1 0.9 0.0 1.8 0.3 0.3 0.0 0.2 0.1 0.0 4.5 PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.9" "Cell type enhanced" "Detected in many" "Astrocytes: 168.5;Distal enterocytes: 154.3;Microglial cells: 74.0;Oligodendrocytes: 298.2;Paneth cells: 80.7;Proximal enterocytes: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 41.8;OE19: 87.9;SuSa: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" 2.7 4.0 83.7 9.2 113.9 1.2 2.3 122.9 86.7 4.7 42.0 38.9 19.3 5.1 8.0 17.6 6.3 6.0 3.5 74.4 89.7 8.0 1.5 7.3 10.3 133.8 110.7 24.3 2.8 5.2 2.2 7.0 123.1 4.3 36.7 2.9 2.2 23.3 0.9 3.1 33.7 6.3 102.8 6.2 32.3 3.7 106.4 9.2 2.8 1.5 7.6 9.7 5.5 144.9 0.9 1.0 10.7 4.6 6.3 10.2 7.3 3.2 12.1 2.0 4.4 4.1 3.8 1.1 1.2 2.2 4.7 0.4 1.4 5.3 3.2 14.8 1.7 6.6 1.0 41.8 1.7 1.8 0.9 2.9 0.7 1.4 7.5 7.4 11.5 12.9 1.5 6.4 8.3 1.5 4.4 6.1 5.4 87.9 0.5 11.5 1.7 2.8 12.4 3.1 4.0 8.7 0.8 0.3 12.4 34.4 0.3 14.7 4.8 4.0 1.6 1.2 1.9 1.9 2.6 1.6 3.7 16.9 21.5 3.0 3.2 1.4 2.8 0.6 4.2 1.1 8.3 5.7 7.0 1.0 17.8 8.3 0.6 8.5 0.6 3.5 6.2 4.2 83.7 113.9 122.9 86.7 74.4 89.7 133.8 110.7 123.1 102.8 106.4 144.9 4.9 3.2 10.6 168.5 3.6 2.0 3.7 3.1 0.6 2.1 0.7 1.3 4.4 14.3 3.5 3.7 8.4 1.7 7.6 154.3 0.0 4.4 0.5 12.2 3.9 7.4 22.9 4.2 21.1 1.1 3.1 6.8 18.8 7.5 4.5 23.7 4.2 0.2 8.8 0.0 19.4 45.5 6.1 19.8 3.5 1.6 5.6 7.3 14.2 74.0 11.4 4.2 3.1 19.1 298.2 4.9 80.7 10.1 0.6 6.6 100.5 0.1 8.9 3.3 0.0 1.0 3.6 12.1 3.3 5.3 1.0 0.8 9.2 10.0 42.5 7.3 PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 455.4;Inhibitory neurons: 147.0;Microglial cells: 193.0;Oligodendrocyte precursor cells: 367.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 97 "granulocytes: 9.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA 21000 "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "HPA030443: AB_10600926" "unprognostic (9.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (2.83e-2)" "unprognostic (1.81e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (3.48e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (5.82e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.54e-1)" "unprognostic (9.20e-2)" "prognostic unfavorable (4.41e-4)" 13.1 15.9 19.6 4.8 17.0 0.5 21.5 10.9 12.4 25.9 16.0 30.4 10.6 20.7 12.2 47.8 20.6 14.9 14.6 17.8 20.6 25.1 22.1 15.2 2.6 15.7 22.1 38.5 34.2 20.7 7.3 21.7 15.9 17.0 21.7 13.6 20.1 23.9 40.5 52.1 13.4 21.8 16.0 4.2 17.7 14.0 24.0 13.5 15.2 30.9 12.4 21.3 30.8 13.9 50.6 121.1 40.1 28.6 28.5 24.2 59.1 22.2 25.4 37.3 40.0 44.3 43.3 0.3 31.4 44.6 30.4 35.8 34.7 56.7 46.1 0.4 26.8 0.0 14.9 44.1 36.2 5.7 0.1 28.7 54.9 50.9 38.1 35.9 23.3 32.4 34.7 14.9 44.8 35.4 59.3 4.2 18.0 32.7 41.4 44.9 39.0 21.9 80.9 38.4 20.1 20.9 26.8 37.3 42.9 49.6 21.1 6.7 28.4 18.7 56.1 35.5 24.2 13.2 17.1 0.1 21.0 0.2 22.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 19.6 17.0 10.9 12.4 17.8 20.6 15.7 22.1 15.9 16.0 24.0 13.9 6.4 35.3 35.3 455.4 0.2 34.0 42.3 19.8 19.9 8.7 17.1 24.9 39.0 21.5 24.3 14.7 29.2 24.9 0.2 25.6 0.0 34.1 19.9 22.3 29.9 9.4 24.0 2.7 5.4 36.4 25.0 22.3 13.3 33.4 1.3 33.1 8.9 24.8 3.4 11.8 147.0 30.1 14.2 0.6 4.7 20.3 30.4 7.7 5.4 193.0 0.8 28.8 1.0 367.9 13.9 38.8 23.8 38.4 1.4 31.4 13.7 25.6 29.3 19.7 26.3 23.4 26.1 6.2 27.6 40.4 61.5 40.1 1.5 32.1 22.0 47.2 PARD3B "ALS2CR19, PAR3beta, Par3L" ENSG00000116117 "Par-3 family cell polarity regulator beta" Q8TEW8 2 204545475-205620162 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 490.7;Microglial cells: 183.6;Oligodendrocyte precursor cells: 159.3;Oligodendrocytes: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 17.8;BJ hTERT+: 12.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035283 Approved Supported "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 64: Astrocytes - Nervous system maintenance" "Cell Junctions" "HPA035283: AB_10671102" "unprognostic (6.18e-2)" "unprognostic (3.86e-1)" "unprognostic (1.05e-1)" "unprognostic (2.41e-2)" "unprognostic (3.61e-2)" "unprognostic (1.73e-1)" "unprognostic (2.69e-1)" "unprognostic (1.67e-2)" "unprognostic (1.57e-1)" "unprognostic (2.38e-1)" "unprognostic (2.20e-1)" "unprognostic (1.43e-1)" "prognostic favorable (2.67e-10)" "unprognostic (1.74e-1)" "unprognostic (8.13e-2)" "unprognostic (1.23e-1)" "unprognostic (8.09e-2)" 9.1 2.8 6.0 1.7 7.3 0.0 5.5 5.3 5.3 4.9 9.3 12.6 3.6 5.1 3.7 4.0 6.5 4.5 4.0 4.6 9.2 6.9 3.4 5.4 2.1 9.3 12.2 7.3 4.9 9.2 1.9 4.4 8.3 4.8 5.5 2.5 3.0 5.2 2.7 4.5 4.2 5.2 8.4 3.1 4.5 3.8 8.0 1.4 5.6 3.6 2.5 5.9 4.0 7.4 2.5 2.1 6.3 2.3 17.8 8.9 3.4 3.8 12.5 3.5 3.8 6.2 1.7 0.0 4.3 7.8 2.8 0.3 0.8 1.0 3.6 0.2 2.9 8.8 5.2 0.0 1.8 0.0 0.5 3.4 1.7 1.2 5.2 5.3 5.2 0.8 0.2 0.1 4.5 1.0 0.0 0.0 0.8 0.9 0.5 0.0 2.7 2.1 3.7 2.5 0.7 2.0 2.0 1.9 1.7 6.2 3.1 0.0 10.9 2.7 1.7 5.5 1.8 0.0 0.0 0.0 2.6 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 7.3 5.3 5.3 4.6 9.2 9.3 12.2 8.3 8.4 8.0 7.4 9.5 9.6 8.6 490.7 0.5 11.0 3.3 2.4 6.8 0.5 5.6 5.8 10.8 15.7 14.5 29.5 0.0 3.2 0.2 12.4 0.0 8.7 76.6 8.5 4.0 6.8 6.0 0.8 5.6 2.4 0.2 16.2 11.7 7.4 1.3 14.1 8.2 4.5 0.5 5.0 50.8 9.2 2.0 1.0 4.3 26.0 31.1 0.6 7.2 183.6 0.1 9.7 0.0 159.3 104.2 6.5 15.9 57.9 1.4 5.0 9.4 4.8 17.0 0.3 19.7 23.5 9.6 1.4 2.9 3.5 4.7 1.1 1.0 2.3 8.0 5.3 PARD6A "PAR-6, PAR-6A, PAR6alpha, TAX40, TIP-40" ENSG00000102981 "Par-6 family cell polarity regulator alpha" Q9NPB6 16 67660946-67662774 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 38.5;testis: 42.9" "Cell type enriched" "Detected in many" 4 "Late spermatids: 266.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "REH: 27.9;RPMI-8226: 24.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009733, HPA041551" Approved Supported "Cell Junctions,Actin filaments,Cytosol" No No "Cluster 24: B-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 25: Spermatids - Spermatogenesis" "Cell Junctions, Actin filaments" Cytosol "CAB009733: AB_2159676, HPA041551: AB_2677545" "prognostic favorable (5.40e-4)" "unprognostic (6.18e-2)" "unprognostic (1.77e-1)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (4.08e-3)" "unprognostic (1.23e-2)" "unprognostic (1.27e-1)" "unprognostic (6.59e-2)" "unprognostic (2.09e-1)" "unprognostic (1.98e-3)" "unprognostic (9.13e-2)" "prognostic favorable (3.08e-7)" "unprognostic (9.22e-3)" "unprognostic (6.69e-2)" "unprognostic (1.25e-1)" "unprognostic (1.39e-2)" 3.2 8.0 25.1 2.4 24.8 1.3 2.8 32.4 38.5 2.1 19.3 7.7 1.1 2.6 2.1 2.0 2.7 1.9 4.2 28.1 22.3 8.8 6.5 3.1 3.1 25.3 22.8 3.9 27.9 6.6 30.2 0.7 26.8 3.6 1.0 2.7 2.7 2.7 8.7 1.8 4.1 1.6 21.9 4.8 5.9 42.9 25.8 3.4 2.4 5.3 2.2 3.7 1.7 25.4 8.9 9.4 2.6 23.5 1.7 0.4 4.7 0.2 1.1 3.4 3.2 4.7 3.6 14.8 4.3 0.3 1.2 7.0 5.2 1.1 0.7 6.9 5.0 6.0 4.1 5.5 2.4 2.5 13.5 0.1 0.5 3.2 1.3 2.1 1.7 21.7 0.6 3.4 0.6 8.7 15.6 3.2 3.3 12.0 6.0 27.9 1.7 24.5 8.8 5.1 21.8 11.7 1.4 3.2 3.7 0.7 19.9 0.9 1.4 0.3 0.8 2.1 4.6 3.5 12.1 13.5 2.6 5.3 1.0 2.1 0.9 0.4 4.3 0.6 7.8 10.9 5.9 5.4 1.1 8.3 2.8 2.2 3.4 1.3 0.1 5.1 6.3 2.0 25.1 24.8 32.4 38.5 28.1 22.3 25.3 22.8 26.8 21.9 25.8 25.4 4.4 3.2 5.8 2.0 17.0 0.9 2.2 1.6 1.2 11.1 7.7 6.7 1.7 10.0 2.6 20.2 4.2 5.7 8.2 3.5 33.2 7.2 61.0 4.1 0.5 3.2 34.0 4.0 7.2 15.0 0.4 3.3 6.1 2.7 5.7 5.2 3.9 4.6 4.3 32.0 7.3 3.3 0.0 4.1 5.7 266.5 3.7 4.7 5.4 3.7 2.2 19.1 1.0 2.0 2.2 6.0 2.1 1.5 12.1 2.1 2.9 16.3 3.4 10.1 0.0 8.0 9.7 5.5 3.9 1.4 1.6 2.9 15.0 1.9 4.7 2.4 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4 PARP6 "ARTD17, pART17" ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 178.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favorable (3.17e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavorable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 20.0 20.9 63.2 14.6 64.8 30.5 20.0 62.2 84.6 22.2 61.2 28.7 15.3 24.5 24.0 17.7 22.6 21.3 19.6 64.5 57.7 23.8 15.5 19.7 19.4 55.7 55.9 29.2 32.5 12.6 49.7 18.3 55.3 25.1 14.8 52.9 23.2 17.3 34.8 23.0 21.7 20.2 51.0 20.6 24.2 34.5 57.1 21.0 30.2 21.2 17.4 22.7 19.1 64.9 15.9 27.6 29.0 37.8 30.5 25.2 23.7 13.8 19.9 21.8 31.1 18.5 28.2 22.3 8.4 20.3 31.4 20.9 32.4 18.1 12.4 26.5 30.6 31.7 55.0 0.2 25.4 16.7 30.1 32.6 43.5 20.1 55.2 33.7 14.6 35.6 16.6 24.3 17.5 28.4 14.4 28.7 14.2 13.2 0.0 26.7 20.8 17.2 19.9 30.4 81.4 43.1 22.6 17.8 37.0 38.2 22.8 18.8 14.0 26.7 24.7 35.7 20.7 27.9 27.7 23.2 19.1 31.4 19.1 1.1 3.6 8.2 2.3 3.1 1.6 2.4 1.7 2.5 2.6 2.3 2.6 2.0 3.6 3.0 3.5 2.2 2.9 2.1 63.2 64.8 62.2 84.6 64.5 57.7 55.7 55.9 55.3 51.0 57.1 64.9 11.5 22.4 21.2 54.9 15.3 14.4 9.6 6.9 31.3 16.4 13.0 13.7 20.9 2.8 12.9 9.2 20.9 7.3 12.0 8.0 7.9 9.7 61.4 8.0 10.3 11.1 17.4 4.6 19.7 12.7 5.3 13.9 21.4 10.0 15.8 17.3 6.4 6.1 8.9 18.5 20.5 6.5 6.1 14.8 11.1 178.1 12.5 14.0 16.0 20.6 9.3 8.8 6.2 27.2 54.6 9.2 9.0 9.8 12.3 9.0 17.7 12.3 5.8 15.5 6.6 13.7 12.5 44.3 12.6 19.3 15.8 6.4 13.3 8.6 7.5 9.3 PATJ "Cipp, INADL" ENSG00000132849 "PATJ crumbs cell polarity complex component" Q8NI35 1 61742477-62178675 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 75.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 86.6;Alveolar cells type 2: 60.6;Club cells: 39.0;Collecting duct cells: 57.0;Endometrial ciliated cells: 55.7;Glandular and luminal cells: 98.3;Pancreatic endocrine cells: 47.9" "Low cancer specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 75.0" "Immune cell enhanced" "Detected in many" "eosinophil: 7.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 36.3;RPTEC TERT1: 30.3;RT4: 33.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 72.3" "HPA066352, HPA066960, HPA069079" Approved Supported "Cell Junctions,Centriolar satellite,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "Centriolar satellite, Cytosol" "HPA066352: AB_2685663, HPA066960: AB_2685755, HPA069079: AB_2686079" "unprognostic (1.81e-1)" "unprognostic (5.70e-3)" "unprognostic (1.75e-2)" "unprognostic (2.32e-1)" "unprognostic (1.34e-1)" "unprognostic (1.35e-1)" "unprognostic (7.96e-2)" "unprognostic (7.60e-2)" "unprognostic (1.88e-1)" "unprognostic (9.90e-2)" "unprognostic (3.39e-3)" "unprognostic (2.99e-2)" "prognostic favorable (1.47e-5)" "unprognostic (3.05e-3)" "unprognostic (6.72e-3)" "unprognostic (2.21e-2)" "unprognostic (2.43e-1)" 3.4 7.2 6.8 3.6 5.4 3.5 18.1 75.0 5.3 8.4 25.3 12.2 8.9 5.8 26.5 19.3 8.3 7.1 45.2 3.8 9.2 27.5 12.4 10.0 2.9 12.8 9.0 6.8 12.4 20.0 10.9 3.5 14.2 12.3 11.1 15.8 20.0 7.9 45.4 22.4 9.3 3.5 11.5 3.1 10.2 5.1 9.1 4.0 13.1 16.1 6.2 7.9 13.2 9.5 36.3 7.0 2.3 3.2 1.3 3.3 29.5 2.1 2.8 2.2 3.0 12.5 13.2 0.2 9.1 4.4 18.7 21.1 5.1 18.9 3.8 3.5 8.8 0.2 10.4 11.3 2.9 0.1 0.2 1.2 19.7 3.7 8.0 5.3 1.2 0.0 0.0 0.0 1.9 12.6 0.1 0.1 12.0 16.4 1.9 0.1 2.8 5.2 30.3 33.4 6.1 2.0 8.8 29.4 7.7 23.7 23.7 0.3 0.3 1.8 4.3 0.2 4.2 1.4 2.7 4.8 1.7 0.0 0.5 0.4 0.0 7.2 1.2 0.1 2.3 1.2 2.0 1.7 0.0 1.1 2.6 1.7 0.6 2.6 0.1 0.2 1.9 0.6 6.8 5.4 75.0 5.3 3.8 9.2 12.8 9.0 14.2 11.5 9.1 9.5 6.4 86.6 60.6 0.0 4.5 0.0 0.0 0.0 0.0 0.0 35.0 29.8 0.0 0.0 39.0 57.0 0.0 4.3 3.8 0.0 5.9 37.6 0.0 55.7 8.6 1.6 0.0 0.0 0.0 26.4 0.7 5.5 0.0 98.3 1.3 14.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.0 0.0 2.7 0.0 0.0 35.7 27.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 26.4 10.3 1.7 0.0 0.0 PAWR "par-4, PAR4" ENSG00000177425 "Pro-apoptotic WT1 regulator" Q96IZ0 12 79574979-79690964 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.7;naive B-cell: 2.8;NK-cell: 1.4" "Group enriched" "Detected in many" 5 "B-cells: 2.8;NK-cells: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012640, CAB020779" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "CAB020779: , HPA012640: AB_1855748" "unprognostic (2.42e-1)" "unprognostic (5.58e-2)" "unprognostic (9.77e-3)" "unprognostic (5.39e-2)" "unprognostic (9.44e-3)" "unprognostic (4.21e-3)" "unprognostic (9.21e-2)" "unprognostic (1.37e-1)" "unprognostic (4.78e-1)" "unprognostic (3.03e-1)" "unprognostic (2.42e-3)" "unprognostic (4.97e-3)" "unprognostic (2.22e-2)" "unprognostic (2.58e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-1)" "unprognostic (4.23e-2)" 11.0 6.1 6.8 9.0 8.0 3.1 13.4 4.8 3.6 20.9 21.6 16.7 11.7 28.0 15.9 14.3 24.7 8.5 5.2 4.7 7.6 12.6 13.3 11.6 6.9 7.7 13.4 20.4 11.6 13.3 8.7 6.2 5.5 14.9 15.3 0.7 14.3 21.8 1.7 16.5 12.1 16.7 5.5 6.2 13.6 10.9 12.4 4.3 16.2 1.8 6.6 16.1 16.4 5.5 54.5 49.1 8.8 0.3 4.4 1.9 58.6 34.1 9.9 17.0 10.3 61.5 20.2 36.2 61.2 19.0 12.2 59.2 31.0 25.7 24.3 14.7 42.2 0.0 28.7 27.1 23.6 0.5 1.0 4.1 53.4 13.4 76.0 63.0 28.7 14.8 2.1 4.9 18.8 41.0 8.8 0.2 42.6 15.7 27.7 0.0 20.2 23.5 32.4 40.4 25.4 0.1 60.8 31.8 5.7 29.4 28.5 0.3 43.2 25.4 22.8 0.9 23.1 15.3 21.6 26.8 4.2 0.1 11.2 0.4 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.2 2.8 0.2 0.2 0.2 1.4 0.0 0.1 0.0 0.0 6.8 8.0 4.8 3.6 4.7 7.6 7.7 13.4 5.5 5.5 12.4 5.5 51.3 80.1 40.7 16.6 33.1 200.1 170.3 42.0 63.2 6.4 93.6 77.3 21.0 60.1 59.2 66.2 0.0 57.1 4.6 103.9 17.6 57.3 62.6 75.7 50.9 31.0 68.8 4.6 1.5 38.5 81.4 41.7 32.1 157.5 1.3 87.4 13.6 54.5 6.5 16.8 50.9 120.9 32.6 1.6 19.2 96.3 84.8 5.3 17.8 23.4 0.4 2.5 4.1 30.7 0.9 83.2 72.0 91.0 11.4 273.4 44.3 47.2 49.9 1.4 85.5 18.3 109.7 98.4 62.1 76.6 179.6 76.9 6.7 62.9 92.7 169.5 PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134905120-135007959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 49.4;tongue: 42.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA036428: AB_10670103" "unprognostic (3.70e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (4.22e-1)" "unprognostic (6.43e-2)" "unprognostic (4.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.57e-2)" "unprognostic (6.34e-2)" "unprognostic (9.32e-3)" "unprognostic (1.50e-1)" 5.3 7.7 7.3 4.8 8.5 7.6 6.0 7.8 7.6 4.3 11.0 6.1 9.5 4.2 4.1 8.3 5.7 4.6 17.1 6.4 7.5 10.2 11.9 4.9 5.9 8.7 7.7 5.1 8.0 13.0 3.8 3.5 8.0 5.4 7.0 9.9 9.6 3.8 49.4 9.2 8.1 3.6 6.8 5.8 8.2 3.2 8.1 5.5 9.6 42.7 6.1 4.5 4.9 10.8 7.5 7.2 9.4 6.9 5.7 5.2 5.2 6.0 5.2 3.8 3.8 12.0 17.5 8.7 8.8 4.4 6.1 6.5 5.6 5.9 3.4 12.3 3.1 6.0 9.5 7.1 5.4 7.1 3.6 3.4 7.1 3.6 7.6 5.1 4.3 7.7 7.7 12.2 6.9 13.0 7.5 12.3 5.1 11.5 6.9 10.9 8.4 9.7 8.1 7.4 7.2 9.2 10.4 6.0 9.1 7.1 13.0 9.4 5.9 6.4 4.3 7.1 8.1 10.6 15.7 5.5 7.8 8.8 4.8 5.7 5.1 5.4 3.6 4.5 2.9 4.5 4.0 3.4 4.4 4.2 3.8 4.3 2.8 4.0 4.6 7.7 3.9 2.7 7.3 8.5 7.8 7.6 6.4 7.5 8.7 7.7 8.0 6.8 8.1 10.8 4.2 9.6 10.3 28.7 8.8 3.6 6.4 15.8 7.4 13.5 11.7 8.4 32.5 20.0 12.5 16.5 12.5 13.6 10.1 13.6 21.5 17.1 8.4 7.9 6.1 6.9 4.2 31.5 10.6 18.2 24.4 5.8 13.3 8.7 6.3 22.4 7.1 23.1 24.6 23.5 12.9 9.5 20.3 10.0 9.6 3.5 7.2 10.2 5.4 17.8 26.9 14.8 7.2 13.0 20.6 17.8 6.2 2.2 13.1 7.1 26.5 26.3 11.9 45.9 0.0 9.0 7.4 5.2 11.5 13.8 6.0 10.1 7.8 9.5 15.9 8.7 PCDH1 pc42 ENSG00000156453 "Protocadherin 1" Q08174 5 141853090-141879246 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 61.5;Distal enterocytes: 66.4;Exocrine glandular cells: 46.3;Pancreatic endocrine cells: 65.2;Urothelial cells: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 86.1;HaCaT: 108.0;HUVEC TERT2: 56.2;OE19: 77.8;RT4: 74.2;TIME: 74.5;WM-115: 52.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047720, HPA050538" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA 2500000 "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" Nucleoli "HPA047720: AB_2680130, HPA050538: AB_2681162" "unprognostic (4.67e-2)" "unprognostic (1.79e-1)" "unprognostic (5.30e-2)" "unprognostic (4.61e-3)" "unprognostic (5.03e-2)" "unprognostic (4.16e-2)" "prognostic unfavorable (4.96e-5)" "unprognostic (1.98e-2)" "unprognostic (4.87e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (3.61e-4)" "unprognostic (2.43e-1)" "prognostic favorable (7.55e-5)" "unprognostic (2.05e-1)" "unprognostic (4.16e-2)" "unprognostic (3.13e-2)" "unprognostic (1.91e-1)" 24.0 4.0 11.7 7.7 15.9 1.2 22.8 3.3 15.1 11.6 0.0 23.1 21.4 9.2 6.4 41.7 9.1 6.6 19.3 17.0 2.3 21.3 19.3 27.7 2.0 0.0 0.8 2.5 13.8 3.8 6.5 19.2 0.0 10.8 14.3 3.4 28.8 11.2 8.2 27.4 17.1 7.2 1.1 1.8 23.6 1.1 2.7 1.0 12.6 11.1 9.1 9.8 19.2 5.7 18.9 1.0 7.7 8.5 0.3 0.0 5.5 0.2 0.2 0.1 0.0 4.5 86.1 0.1 43.7 0.6 1.0 108.0 9.9 7.9 0.0 0.1 0.3 0.0 0.4 0.1 6.9 0.0 0.3 0.0 17.8 0.1 1.2 18.1 56.2 0.0 0.1 9.2 0.0 15.1 0.3 0.0 32.5 77.8 14.6 0.3 0.1 13.2 6.3 74.2 0.9 1.8 0.5 23.3 20.0 21.6 18.8 0.4 74.5 0.1 0.7 0.1 6.9 0.0 0.1 0.2 0.5 0.0 52.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 11.7 15.9 3.3 15.1 17.0 2.3 0.0 0.8 0.0 1.1 2.7 5.7 61.5 0.0 5.3 3.6 0.2 1.0 12.0 4.6 0.0 9.6 9.5 4.7 4.4 20.0 8.6 12.9 0.0 0.7 2.0 66.4 3.9 15.3 1.3 10.1 2.1 34.2 7.7 2.7 12.3 46.3 0.3 2.6 21.9 21.3 0.0 0.0 7.5 30.1 0.2 26.9 6.1 21.3 12.2 1.4 2.3 2.5 0.6 0.5 0.0 6.5 0.0 4.8 7.2 5.5 7.2 65.2 30.3 0.4 1.4 25.8 36.4 5.2 7.1 0.5 13.1 0.9 18.5 0.3 0.2 7.4 2.6 20.1 0.9 0.5 18.9 54.5 PCDH17 "PCDH68, PCH68" ENSG00000118946 "Protocadherin 17" O14917 13 57631744-57729311 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 27.9;lymphoid tissue: 25.1" "Group enriched" "Detected in many" 4 "Adipocytes: 57.6;Astrocytes: 77.1;Early spermatids: 60.7;Endothelial cells: 126.7;Excitatory neurons: 125.2;Hepatic stellate cells: 79.6;Inhibitory neurons: 67.9;Oligodendrocyte precursor cells: 193.0;Oligodendrocytes: 101.1;Spermatocytes: 68.3" "Cancer enhanced" "Detected in many" "glioma: 9.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 14.7;HEK 293: 9.3;U-87 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026817 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA 690000 "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Cytosol" "Plasma membrane" "HPA026817: AB_1855044" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.19e-1)" "unprognostic (6.52e-2)" "unprognostic (6.98e-3)" "unprognostic (1.95e-2)" "unprognostic (8.26e-4)" "unprognostic (3.56e-1)" "unprognostic (2.38e-2)" "unprognostic (2.82e-1)" "unprognostic (5.40e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.31e-5)" "unprognostic (1.07e-2)" "unprognostic (1.80e-1)" "unprognostic (2.35e-1)" "unprognostic (3.40e-2)" 1.6 1.8 15.8 1.8 20.6 0.0 0.8 7.9 13.9 2.2 0.1 1.2 0.8 2.1 0.8 0.6 2.0 3.2 2.2 11.7 25.5 1.9 1.0 14.0 0.6 9.3 15.8 0.5 6.0 1.6 0.9 4.4 11.4 1.0 0.8 1.0 0.7 0.7 1.7 0.3 0.8 2.1 7.6 25.1 1.5 8.8 27.9 0.2 2.9 1.3 0.5 2.7 0.8 10.5 0.0 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 9.3 0.4 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.3 0.0 2.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.4 1.2 0.0 1.0 0.0 0.0 0.0 5.3 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.8 20.6 7.9 13.9 11.7 25.5 9.3 15.8 11.4 7.6 27.9 10.5 57.6 0.0 4.3 77.1 0.1 2.7 0.1 0.0 1.2 7.1 0.4 0.6 6.0 1.5 8.6 1.8 0.0 0.2 0.5 0.1 0.0 11.1 60.7 2.6 2.0 126.7 0.0 0.0 125.2 8.3 0.1 11.7 0.0 19.8 0.0 20.5 79.6 0.3 0.6 0.0 67.9 0.0 0.0 1.9 2.5 19.0 1.8 0.5 10.6 12.2 1.6 2.3 0.0 193.0 101.1 1.3 0.0 1.2 1.2 0.3 0.0 0.0 5.1 0.0 6.6 1.9 10.7 68.3 10.6 0.4 1.0 0.0 1.1 1.6 0.0 0.4 PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720415-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Group enriched" "Detected in many" 8 "Astrocytes: 311.8;Excitatory neurons: 1152.0;Inhibitory neurons: 882.3;Oligodendrocyte precursor cells: 917.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 43.4;RH-30: 120.4;RT4: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" 1.8 3.2 10.5 5.2 14.6 0.0 3.0 0.0 33.7 23.9 0.0 19.2 3.2 16.9 25.1 14.3 9.7 8.1 19.1 23.7 50.1 2.0 1.0 2.9 1.4 13.0 14.3 4.7 0.9 1.1 0.2 0.2 14.3 10.6 7.8 3.4 0.8 18.2 0.6 11.6 5.0 22.1 3.9 18.6 11.4 1.0 46.3 1.4 4.1 0.4 1.2 16.3 5.9 11.8 0.0 1.1 14.4 20.1 29.5 28.5 0.0 3.8 0.0 1.9 0.9 1.9 26.5 0.0 0.1 0.2 0.0 15.3 1.3 38.5 3.4 0.0 43.4 0.1 26.8 0.0 30.4 0.6 0.0 17.2 8.8 1.0 10.7 17.5 7.5 0.0 0.0 0.0 9.0 0.1 0.0 0.1 8.8 9.3 4.0 0.0 120.4 0.0 0.9 65.2 0.9 0.2 0.4 1.2 1.3 8.2 1.8 6.9 0.0 24.1 6.2 6.7 0.0 0.0 0.0 0.0 18.8 0.1 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 14.6 0.0 33.7 23.7 50.1 13.0 14.3 14.3 3.9 46.3 11.8 1.1 0.0 0.0 311.8 0.3 85.0 92.4 25.7 46.7 46.8 0.7 9.0 83.2 0.0 13.7 64.4 0.0 0.1 0.0 0.3 0.0 0.6 16.9 66.8 8.4 7.6 0.0 0.0 1152.0 0.7 0.1 24.0 20.9 60.4 1.3 0.8 19.2 0.1 0.3 10.1 882.3 0.5 4.1 1.0 3.5 10.4 0.3 1.3 21.4 43.1 0.0 1.3 0.0 917.3 26.4 26.5 0.0 28.6 1.3 26.1 0.0 0.2 27.0 3.4 0.0 51.3 11.0 1.1 2.7 18.5 38.6 0.1 1.8 1.7 0.3 50.3 PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Hepatic stellate cells: 1.4;Sertoli cells: 6.6;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "T-47d: 9.1" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" 0.0 0.2 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 0.0 0.0 1.5 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 1.1 0.1 9.1 0.3 0.0 1.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.5 1.0 0.7 0.4 1.5 0.7 1.1 0.9 0.5 1.9 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA11 "CNR7, CNRN7, CNRS7, CRNR7, PCDH-ALPHA11" ENSG00000249158 "Protocadherin alpha 11" Q9Y5I1 5 140868183-141012347 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.2;parathyroid gland: 2.7;retina: 2.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 4.0;AN3-CA: 10.7;EFO-21: 7.6;MCF7: 4.4;T-47d: 6.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA077160 Approved "Vesicles,Cell Junctions,Cytoplasmic bodies" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Cell Junctions" "Cytoplasmic bodies" "HPA077160: AB_2686827" "unprognostic (1.54e-2)" "unprognostic (1.83e-3)" "unprognostic (2.75e-1)" "unprognostic (2.59e-1)" "unprognostic (6.98e-3)" "unprognostic (1.36e-1)" "unprognostic (9.28e-3)" "unprognostic (2.40e-3)" "unprognostic (2.53e-2)" "unprognostic (1.53e-2)" "unprognostic (2.27e-2)" "unprognostic (3.13e-4)" "unprognostic (9.91e-5)" "unprognostic (1.05e-1)" "unprognostic (3.85e-3)" "unprognostic (3.26e-2)" 0.2 0.3 1.5 0.1 1.3 0.0 0.2 4.2 2.2 0.8 0.0 0.1 0.0 0.5 0.1 0.0 0.2 0.8 0.0 1.1 0.3 0.7 0.1 0.4 0.1 0.0 1.5 0.0 1.8 2.7 1.0 0.0 0.3 0.1 0.0 2.4 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.7 0.0 2.1 4.0 10.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.6 0.0 0.8 0.0 0.1 1.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.4 0.3 0.0 1.0 0.0 0.1 0.0 4.4 0.0 0.0 3.5 0.8 2.8 0.0 0.0 0.0 0.4 1.6 0.2 1.9 0.0 1.9 0.4 1.9 6.5 0.0 0.0 0.7 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.3 4.2 2.2 1.1 0.3 0.0 1.5 0.3 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 28.9;Alveolar cells type 2: 5.1;Bipolar cells: 11.4;Cone photoreceptor cells: 6.2;Horizontal cells: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 3.9;cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.1;hTCEpi: 3.4;PC-3: 5.1;RT4: 5.2;SH-SY5Y: 2.1" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA035812: AB_2674796" "unprognostic (3.95e-2)" "unprognostic (7.74e-2)" "unprognostic (7.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-2)" "unprognostic (2.24e-2)" "unprognostic (2.08e-2)" "unprognostic (4.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-4)" "unprognostic (3.18e-4)" "unprognostic (1.11e-1)" "unprognostic (3.21e-3)" "unprognostic (6.97e-2)" 0.3 0.3 0.4 0.0 0.5 0.0 0.2 3.9 1.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.7 0.0 0.3 0.1 0.6 0.1 1.5 0.0 0.3 0.1 0.0 0.7 0.0 0.8 0.0 0.4 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 7.1 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.6 1.7 5.1 0.0 0.0 0.0 0.1 5.2 0.2 2.1 0.0 0.6 0.0 0.3 1.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 3.9 1.1 0.3 0.1 0.3 0.1 0.4 0.1 0.0 0.5 0.2 28.9 5.1 0.0 0.0 0.0 0.0 0.8 0.0 11.4 0.8 1.3 0.4 4.3 1.9 1.8 6.2 0.0 0.0 0.1 0.0 0.7 1.3 0.8 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.8 0.0 0.1 1.4 0.1 0.0 5.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.1 0.0 0.2 1.3 3.6 0.0 0.2 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PCDHA4 "CNR1, CNRN1, CRNR1, PCDH-ALPHA4" ENSG00000204967 "Protocadherin alpha 4" Q9UN74 5 140806929-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 2.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.0;granulocytes: 3.8;Respiratory ciliated cells: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.6;AF22: 5.6;EFO-21: 5.1;T-47d: 5.4" "Not detected" "Not detected" "HPA043180, HPA073478" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 6: Brain - Smell perception" "Cluster 38: EFO-21 - Unknown function" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Plasma membrane" Cytosol "HPA043180: AB_10806381, HPA073478: AB_2686608" "unprognostic (2.71e-3)" "unprognostic (1.16e-1)" "unprognostic (2.85e-1)" "unprognostic (5.32e-2)" "unprognostic (1.93e-1)" "unprognostic (3.14e-2)" "unprognostic (2.56e-1)" "unprognostic (7.90e-3)" "unprognostic (7.14e-3)" "unprognostic (7.00e-2)" "unprognostic (5.06e-3)" "unprognostic (6.94e-5)" "unprognostic (5.01e-3)" "unprognostic (6.21e-2)" "unprognostic (3.98e-1)" "unprognostic (6.29e-3)" "unprognostic (4.79e-2)" 0.2 0.2 0.9 0.2 1.2 0.9 0.4 2.9 1.1 0.5 0.0 0.3 0.3 0.6 0.4 0.1 0.3 1.3 0.1 0.9 0.5 0.4 0.1 0.4 0.3 0.6 0.5 0.2 1.2 0.1 0.4 0.1 0.6 0.4 0.2 0.9 0.2 0.3 0.3 0.5 0.2 0.3 0.3 0.3 0.3 0.4 0.4 0.1 0.3 0.1 0.2 0.2 0.1 1.5 0.1 6.6 5.6 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 1.1 0.1 5.1 0.1 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.2 0.4 0.2 0.1 0.2 0.3 0.3 1.1 0.1 0.1 0.3 0.3 0.2 0.1 0.7 0.1 0.1 0.1 0.2 1.7 1.2 0.9 0.1 0.1 0.2 0.1 0.2 0.2 2.3 0.0 1.4 0.5 0.8 5.4 0.1 0.6 1.2 0.8 0.5 0.1 0.3 0.1 0.1 0.2 0.2 0.5 0.3 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.9 1.2 2.9 1.1 0.9 0.5 0.6 0.5 0.6 0.3 0.4 1.5 0.1 3.2 2.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.2 0.0 0.8 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.3 0.6 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.3 3.8 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 0.0 0.2 2.9 1.1 0.0 0.4 0.5 1.0 0.5 0.0 0.0 0.0 0.2 0.1 0.1 0.4 PCDHA5 "CNR6, CNRN6, CNRS6, CRNR6, PCDH-ALPHA5" ENSG00000204965 "Protocadherin alpha 5" Q9Y5H7 5 140821604-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "brain: 3.3" "Cell type enriched" "Detected in some" 4 "Horizontal cells: 6.7" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.3;EFO-21: 3.4;T-47d: 3.7;WM-115: 1.3" "Low region specificity" "Detected in many" HPA044557 Approved Approved "Nuclear speckles,Plasma membrane,Mitochondria" NA NA "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles, Mitochondria" "HPA044557: AB_10970597" "unprognostic (4.95e-2)" "unprognostic (6.23e-2)" "unprognostic (2.06e-1)" "unprognostic (8.81e-4)" "unprognostic (5.10e-2)" "unprognostic (6.25e-3)" "unprognostic (6.74e-2)" "unprognostic (9.79e-2)" "unprognostic (2.46e-2)" "unprognostic (4.49e-2)" "unprognostic (1.44e-2)" "unprognostic (1.10e-4)" "unprognostic (9.30e-4)" "unprognostic (1.07e-1)" "unprognostic (1.39e-1)" "unprognostic (8.17e-5)" "unprognostic (2.11e-1)" 0.1 0.1 0.6 0.0 1.0 0.0 0.1 3.3 1.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 1.3 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 1.0 3.3 1.1 0.9 0.0 0.1 0.1 0.2 0.0 0.1 0.6 0.3 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 6.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB1 PCDH-BETA1 ENSG00000171815 "Protocadherin beta 1" Q9Y5F3 5 141051374-141059346 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Cardiomyocytes: 2.7;Respiratory ciliated cells: 2.2;Skeletal myocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053921 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA053921: AB_2682310" "unprognostic (5.54e-2)" "unprognostic (1.60e-2)" "unprognostic (9.01e-4)" "unprognostic (8.65e-2)" "unprognostic (8.00e-2)" "unprognostic (7.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (8.17e-5)" "unprognostic (3.38e-2)" "unprognostic (9.40e-2)" "unprognostic (1.23e-1)" "unprognostic (5.77e-4)" 0.1 0.2 0.4 0.1 0.4 0.4 0.0 0.9 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.4 0.1 0.1 0.4 0.2 0.3 0.1 0.1 0.2 0.4 0.3 0.1 0.4 0.3 0.5 0.1 0.4 0.1 0.0 0.5 0.2 0.0 1.4 0.3 0.2 0.0 0.1 0.2 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.5 0.0 0.2 0.1 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.2 0.4 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.4 0.4 0.9 0.5 0.4 0.2 0.4 0.3 0.4 0.1 0.3 0.4 0.0 0.0 1.1 0.0 0.4 0.0 0.9 0.0 0.0 0.3 0.1 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.2 0.4 0.0 1.2 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 4.9;Endometrial stromal cells: 3.5;Fibroblasts: 4.8;Peritubular cells: 3.4;Sertoli cells: 6.6;Skeletal myocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.6;EFO-21: 8.9;U-2 OS: 3.0" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" 1.3 0.6 0.2 0.5 0.5 0.2 0.9 0.9 1.2 1.2 0.0 1.0 0.2 1.5 0.5 0.7 0.9 0.9 0.8 0.5 0.0 0.7 0.2 0.8 0.1 0.3 0.3 1.6 2.6 2.6 0.7 0.6 0.1 0.9 0.3 0.6 0.8 1.0 0.4 0.8 0.4 1.2 0.4 0.6 0.6 0.4 0.0 0.3 0.6 0.6 0.1 0.9 0.6 0.4 0.0 0.1 1.8 5.6 0.1 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.9 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.0 0.0 0.2 2.2 0.3 1.3 0.1 0.7 0.3 1.3 0.0 0.3 0.1 3.0 2.4 0.0 0.1 0.0 0.0 1.4 0.1 1.5 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.9 1.2 0.5 0.0 0.3 0.3 0.1 0.4 0.0 0.4 1.9 3.2 0.5 0.0 0.0 0.0 0.7 0.0 0.0 4.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 3.5 1.9 2.4 0.0 0.0 1.8 0.0 4.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 3.4 0.1 0.9 0.0 0.9 0.0 0.2 6.6 4.1 1.7 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.7 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB4 PCDH-BETA4 ENSG00000081818 "Protocadherin beta 4" Q9Y5E5 5 141121818-141125623 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 9.7;Endometrial stromal cells: 8.2;Fibroblasts: 9.5;Horizontal cells: 8.4;Peritubular cells: 6.4;Skeletal myocytes: 8.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "SCLC-21H: 8.7;SH-SY5Y: 5.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014466 Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA014466: AB_1855058" "unprognostic (2.60e-1)" "unprognostic (1.18e-1)" "unprognostic (1.34e-1)" "unprognostic (2.22e-1)" "unprognostic (8.60e-3)" "unprognostic (4.03e-1)" "unprognostic (6.44e-2)" "unprognostic (2.44e-1)" "unprognostic (8.66e-2)" "unprognostic (1.52e-1)" "unprognostic (6.70e-3)" "unprognostic (1.44e-1)" "unprognostic (2.82e-3)" "unprognostic (1.11e-3)" "unprognostic (2.17e-1)" "unprognostic (3.32e-4)" "unprognostic (5.18e-3)" 3.2 2.1 2.7 0.7 3.0 0.0 3.4 3.3 3.7 3.6 0.3 2.0 0.6 5.4 3.8 1.5 4.0 2.4 2.3 3.2 4.2 1.5 0.3 2.1 0.4 5.0 3.7 4.2 8.5 1.4 2.7 0.1 5.7 2.4 0.9 1.6 2.1 1.9 1.6 1.3 0.9 3.3 5.0 0.7 1.3 0.5 2.7 0.4 1.5 2.1 0.2 2.1 2.1 6.7 0.0 0.0 0.3 1.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 8.7 5.8 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 2.7 3.0 3.3 3.7 3.2 4.2 5.0 3.7 5.7 5.0 2.7 6.7 9.7 0.0 0.5 0.0 0.0 1.1 0.4 0.2 0.6 4.9 2.6 3.8 1.2 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.4 8.2 4.3 0.0 0.0 0.0 1.7 0.0 9.5 0.0 0.3 0.0 0.1 3.6 0.0 0.1 8.4 0.0 0.0 2.0 0.0 1.1 0.0 1.5 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 0.6 0.0 6.4 0.0 0.7 0.0 0.0 2.5 0.6 0.0 8.7 4.0 1.4 0.5 0.0 2.0 0.0 0.0 0.5 0.0 0.4 PCDHB5 "DKFZp586B0217, PCDH-BETA5" ENSG00000113209 "Protocadherin beta 5" Q9Y5E4 5 141135206-141138615 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.2;Early spermatids: 8.2;Muller glia cells: 5.0;Spermatocytes: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 18.7;GAMG: 13.9;NTERA-2: 17.7;RH-30: 14.0;SCLC-21H: 16.4;SuSa: 21.7;T-47d: 17.6;U-138 MG: 32.4;U-2 OS: 14.1;WM-115: 14.7" "Low region specificity" "Detected in many" "HPA013191, HPA067473" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Vesicles "HPA013191: AB_1855059, HPA067473: " "unprognostic (2.21e-1)" "unprognostic (4.71e-2)" "unprognostic (4.05e-3)" "unprognostic (1.81e-1)" "unprognostic (2.84e-2)" "unprognostic (5.23e-2)" "unprognostic (2.27e-2)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.06e-3)" "unprognostic (6.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-3)" 1.4 1.6 2.2 0.4 1.7 0.0 1.6 1.1 3.2 3.4 0.0 1.4 0.2 4.2 3.5 0.7 2.8 1.8 1.9 2.8 0.6 2.4 0.7 1.7 0.2 2.5 1.6 5.9 4.7 2.7 3.2 0.4 1.3 2.9 0.3 2.4 2.2 2.1 1.1 0.6 0.6 2.1 1.7 0.7 1.0 3.1 1.8 0.4 2.5 0.6 0.1 1.6 1.3 2.3 0.0 1.0 18.7 0.3 1.3 0.8 0.2 0.4 0.1 0.3 0.3 0.0 0.0 0.0 9.6 0.0 13.9 0.0 9.8 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.7 0.0 0.0 0.1 3.8 0.9 0.0 0.7 0.1 0.0 0.0 0.1 0.0 17.7 0.0 0.0 0.0 14.0 0.0 0.0 0.0 16.4 0.5 0.0 0.2 6.1 21.7 17.6 4.3 0.0 32.4 14.1 5.3 0.0 0.0 0.0 0.0 1.7 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.7 1.1 3.2 2.8 0.6 2.5 1.6 1.3 1.7 1.8 2.3 1.9 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.6 5.2 0.9 2.2 1.1 1.5 1.8 1.8 0.0 0.0 0.0 0.0 0.0 2.5 8.2 0.5 4.3 1.1 0.0 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.5 0.4 0.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.2 0.0 4.5 0.0 1.1 0.0 0.5 0.1 0.7 0.0 2.1 2.7 13.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.6 PCDHGA1 PCDH-GAMMA-A1 ENSG00000204956 "Protocadherin gamma subfamily A, 1" Q9Y5H4 5 141330571-141512981 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 2.4;Cardiomyocytes: 1.8;Horizontal cells: 3.3" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 4.5;T-47d: 7.3;WM-115: 3.3" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA036547" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 6: T47d - Mammary gland" "Cluster 37: Myocytes - Muscle contraction" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA036547: AB_10669798" "unprognostic (9.50e-4)" "unprognostic (2.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.42e-3)" "unprognostic (3.39e-1)" "unprognostic (3.97e-2)" "unprognostic (2.42e-1)" "unprognostic (5.61e-3)" "unprognostic (1.70e-2)" "unprognostic (6.89e-2)" "unprognostic (2.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.07e-3)" "unprognostic (4.76e-2)" "unprognostic (1.38e-1)" "unprognostic (2.73e-2)" "unprognostic (1.45e-3)" 0.3 0.2 1.1 0.2 2.3 0.2 0.2 3.2 2.0 0.5 0.0 0.5 0.2 0.6 0.9 0.2 0.4 0.1 1.2 2.2 0.9 0.2 0.1 0.3 0.1 1.5 1.4 0.6 0.5 0.5 0.9 0.5 0.9 0.3 0.2 1.0 0.2 0.2 0.7 0.3 0.1 0.4 1.7 0.2 0.1 0.7 1.4 0.1 0.2 0.4 0.1 0.4 0.3 1.3 0.0 0.2 0.3 1.1 0.7 1.3 0.1 1.1 0.7 0.3 0.6 0.3 0.1 0.2 1.8 0.7 0.5 0.1 0.1 0.2 0.7 0.1 0.1 0.1 0.2 0.1 0.2 0.0 0.1 1.1 0.3 0.0 0.4 2.1 0.0 0.1 0.1 0.5 4.5 0.0 0.1 0.5 0.1 0.0 0.2 2.0 1.6 0.2 0.2 0.2 1.0 1.3 0.1 0.6 1.1 0.3 7.3 0.2 0.5 2.0 0.3 1.0 0.2 0.1 0.6 0.1 2.4 0.1 3.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 1.1 2.3 3.2 2.0 2.2 0.9 1.5 1.4 0.9 1.7 1.4 1.3 0.3 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.3 0.1 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 PCDHGA10 PCDH-GAMMA-A10 ENSG00000253846 "Protocadherin gamma subfamily A, 10" Q9Y5H3 5 141412987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 27.7;Cone photoreceptor cells: 16.7;Horizontal cells: 23.5;Skeletal myocytes: 14.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.6;HSkMC: 16.1;T-47d: 19.7;U-2197: 11.6" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077276" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 6: T47d - Mammary gland" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077276: " "unprognostic (2.92e-1)" "unprognostic (2.17e-4)" "unprognostic (1.63e-1)" "unprognostic (3.33e-2)" "unprognostic (1.12e-1)" "unprognostic (3.05e-2)" "unprognostic (9.99e-2)" "unprognostic (1.06e-2)" "unprognostic (2.01e-1)" "unprognostic (2.02e-1)" "unprognostic (4.39e-2)" "unprognostic (2.03e-2)" "unprognostic (2.64e-3)" "unprognostic (2.32e-3)" "unprognostic (1.34e-1)" "unprognostic (2.06e-1)" "unprognostic (8.83e-3)" 1.6 1.6 3.5 0.4 3.2 0.1 1.1 4.1 2.4 1.3 0.8 1.0 0.8 1.3 0.7 1.7 1.3 1.4 1.0 2.7 3.8 0.5 1.5 1.3 0.4 3.3 3.1 1.3 0.6 2.1 0.8 3.6 3.4 1.4 0.9 2.5 1.8 1.8 1.1 2.0 1.0 1.1 4.2 0.9 2.0 0.5 3.9 0.4 2.1 0.3 0.5 0.8 1.3 3.8 0.0 0.0 14.6 7.5 6.3 2.7 6.9 2.6 0.1 3.6 5.6 0.3 0.9 0.8 9.6 3.7 0.2 0.4 3.5 2.4 2.8 0.9 0.1 0.0 0.3 0.0 2.5 1.5 0.3 16.1 0.4 2.4 1.0 0.4 1.4 0.3 0.0 0.1 9.0 0.1 0.1 0.4 1.4 0.0 0.1 0.2 1.2 0.0 2.4 0.1 2.0 0.7 0.4 0.1 0.4 3.5 19.7 1.9 3.3 6.7 0.4 11.6 0.1 0.2 1.2 0.1 3.4 0.0 0.4 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.5 3.2 4.1 2.4 2.7 3.8 3.3 3.1 3.4 4.2 3.9 3.8 5.8 0.0 2.0 0.0 0.9 0.1 2.3 0.6 1.2 27.7 2.2 2.2 3.4 1.5 1.6 1.8 16.7 2.1 1.3 0.7 0.0 1.0 0.0 1.3 7.7 4.8 1.2 0.4 0.0 1.4 1.3 4.8 1.5 2.0 1.3 1.0 4.6 1.7 1.0 23.5 0.0 1.6 0.0 0.0 0.0 0.2 3.4 0.7 1.8 0.0 0.0 5.7 0.0 0.0 0.0 3.1 0.4 2.2 0.5 2.8 0.4 0.5 0.0 6.7 6.6 14.9 3.7 0.4 0.7 1.2 0.4 0.4 0.5 3.0 1.3 1.5 PCDHGA11 PCDH-GAMMA-A11 ENSG00000253873 "Protocadherin gamma subfamily A, 11" Q9Y5H2 5 141421047-141512975 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Bipolar cells: 2.5;Hepatic stellate cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 24.3;ASC TERT1: 25.9;GAMG: 47.4;hTERT-RPE1: 69.8;WM-115: 43.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.13e-2)" "unprognostic (1.78e-3)" "unprognostic (9.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.68e-2)" "unprognostic (2.62e-1)" "unprognostic (2.70e-2)" "unprognostic (1.16e-3)" "unprognostic (1.09e-1)" "unprognostic (1.95e-2)" "unprognostic (2.97e-1)" "unprognostic (2.22e-1)" "unprognostic (3.03e-2)" "unprognostic (3.74e-2)" "unprognostic (3.54e-1)" "unprognostic (4.34e-3)" "unprognostic (1.89e-1)" 0.8 0.7 1.4 0.7 1.8 0.0 0.6 5.1 1.3 0.8 0.7 1.0 0.2 0.7 0.3 0.7 0.9 0.5 1.6 2.1 2.3 0.5 0.4 0.6 0.4 1.8 1.2 1.1 0.5 0.3 0.6 2.2 2.1 0.5 0.3 3.1 0.7 0.7 1.1 1.7 0.4 0.8 2.4 0.3 0.4 0.8 1.9 0.3 0.8 0.5 0.3 0.6 0.8 2.9 0.0 0.0 0.7 2.4 24.3 25.9 0.9 5.5 10.6 4.2 6.6 0.1 0.2 0.6 9.1 5.6 47.4 3.7 0.1 0.6 6.6 0.2 2.4 0.1 0.1 0.0 4.0 0.4 0.0 19.0 0.3 7.4 0.1 69.8 6.5 1.2 0.0 0.1 0.1 0.0 0.0 0.3 2.9 0.0 0.1 17.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 21.3 9.9 0.5 3.2 7.9 0.8 0.1 0.6 0.1 0.0 0.4 0.0 0.1 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.4 1.8 5.1 1.3 2.1 2.3 1.8 1.2 2.1 2.4 1.9 2.9 0.5 0.0 1.1 0.0 0.0 0.0 0.2 0.0 0.0 2.5 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.7 0.1 0.5 0.8 0.0 0.0 0.0 0.2 0.3 0.5 0.0 0.1 0.0 0.2 1.1 0.0 0.4 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.4 0.0 0.3 0.0 0.1 0.0 0.6 0.0 0.6 0.3 0.1 0.1 0.7 0.0 0.1 0.0 0.2 0.1 0.1 PCDHGA12 "CDH21, FIB3, KIAA0588, PCDH-GAMMA-A12" ENSG00000253159 "Protocadherin gamma subfamily A, 12" O60330 5 141430507-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.0" "Cell type enhanced" "Detected in some" "Adipocytes: 2.2;Bipolar cells: 3.8;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.3;Endothelial cells: 2.2;Fibroblasts: 3.2;Skeletal myocytes: 2.0" "Group enriched" "Detected in many" 5 "glioma: 1.7;melanoma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in some" "BJ: 9.3;BJ hTERT+: 15.4;fHDF/TERT166: 23.3;HHSteC: 7.2;HSkMC: 16.5;TIME: 7.5" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA 21000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.17e-3)" "unprognostic (2.71e-2)" "unprognostic (1.04e-2)" "unprognostic (2.67e-1)" "unprognostic (2.74e-1)" "unprognostic (5.06e-2)" "unprognostic (1.99e-1)" "unprognostic (9.01e-3)" "unprognostic (1.19e-1)" "unprognostic (4.65e-4)" "unprognostic (2.98e-1)" "unprognostic (3.02e-1)" "unprognostic (1.28e-4)" "unprognostic (8.30e-3)" "unprognostic (1.57e-1)" "unprognostic (2.42e-1)" "unprognostic (6.85e-3)" 3.0 4.3 5.3 0.8 6.8 0.0 1.5 5.5 3.7 2.0 0.8 1.3 0.2 2.6 0.4 1.0 1.9 3.9 4.2 5.1 8.4 1.0 0.7 3.1 0.4 10.0 4.2 1.9 1.1 0.3 1.4 2.2 4.5 1.0 0.3 1.4 0.9 1.5 1.3 1.7 0.8 1.7 5.5 1.2 1.0 0.3 5.2 0.9 1.6 1.1 0.4 1.2 2.0 4.6 0.0 0.0 0.1 1.9 0.8 1.4 0.1 9.3 15.4 0.0 0.0 0.0 0.0 0.5 0.0 23.3 0.1 2.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 7.2 0.0 0.0 16.5 0.0 4.5 0.0 0.0 5.4 0.0 0.0 0.0 3.2 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 2.6 7.5 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.3 6.8 5.5 3.7 5.1 8.4 10.0 4.2 4.5 5.5 5.2 4.6 2.2 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 3.8 0.2 0.6 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.3 2.2 0.0 0.0 0.0 0.2 0.0 3.2 1.1 0.1 0.0 0.1 0.7 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.7 0.0 2.0 1.0 0.0 0.0 0.4 0.0 0.0 0.1 0.7 0.0 0.0 PCDHGA2 PCDH-GAMMA-A2 ENSG00000081853 "Protocadherin gamma subfamily A, 2" Q9Y5H1 5 141338760-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 3.2;Cardiomyocytes: 1.8;Fibroblasts: 1.5;Leydig cells: 1.2;Peritubular cells: 2.6;Skeletal myocytes: 1.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.4;BJ: 3.9;fHDF/TERT166: 4.4;HSkMC: 3.4;hTERT-RPE1: 3.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA038625" Approved Approved "Nucleoplasm,Nucleoli,Vesicles,Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Nucleoli, Focal adhesion sites, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA038625: AB_2732480" "unprognostic (2.43e-3)" "unprognostic (2.10e-2)" "unprognostic (1.32e-2)" "unprognostic (4.54e-1)" "unprognostic (2.92e-1)" "unprognostic (1.14e-1)" "unprognostic (3.01e-1)" "unprognostic (2.82e-1)" "unprognostic (1.56e-1)" "unprognostic (1.18e-1)" "unprognostic (9.01e-2)" "unprognostic (4.32e-2)" "unprognostic (8.45e-3)" "unprognostic (9.68e-3)" "unprognostic (1.04e-2)" "unprognostic (1.18e-2)" "unprognostic (2.23e-4)" 2.2 1.6 1.8 0.7 1.4 0.0 1.9 2.7 2.5 3.0 0.7 1.5 0.1 2.9 1.9 0.8 3.1 1.4 4.9 2.9 1.5 1.1 0.7 2.0 0.2 3.8 3.2 6.3 1.8 3.8 2.6 0.7 2.6 1.9 0.3 2.3 1.2 2.2 1.0 1.0 0.6 2.1 3.5 0.6 0.9 2.3 2.6 0.8 1.6 1.1 0.2 1.4 1.7 2.2 0.0 0.7 0.3 0.2 2.8 6.4 0.0 3.9 1.3 0.3 0.5 0.0 0.0 0.1 0.4 4.4 0.5 0.1 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.4 0.1 0.0 0.2 3.9 1.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.5 0.0 0.2 0.5 0.0 2.3 0.1 0.3 0.4 0.0 2.3 0.6 0.3 0.2 0.0 0.0 0.3 0.0 1.5 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.4 2.7 2.5 2.9 1.5 3.8 3.2 2.6 3.5 2.6 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 3.2 0.3 0.9 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 1.1 0.9 0.0 0.0 0.0 0.2 0.0 1.5 0.0 0.1 0.0 0.1 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 0.4 0.0 0.4 0.0 1.5 0.5 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGA3 PCDH-GAMMA-A3 ENSG00000254245 "Protocadherin gamma subfamily A, 3" Q9Y5H0 5 141343829-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.4;Cardiomyocytes: 1.6;Endometrial stromal cells: 1.9;Fibroblasts: 1.3;Horizontal cells: 3.3;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 7.1;BJ: 2.3;EFO-21: 5.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.47e-2)" "unprognostic (4.79e-2)" "unprognostic (1.48e-2)" "unprognostic (1.64e-1)" "unprognostic (4.53e-2)" "unprognostic (1.03e-1)" "unprognostic (2.35e-1)" "unprognostic (1.85e-1)" "unprognostic (7.44e-2)" "unprognostic (1.08e-1)" "unprognostic (1.28e-1)" "unprognostic (3.17e-2)" "unprognostic (2.43e-1)" "unprognostic (2.32e-3)" "unprognostic (7.12e-3)" "unprognostic (3.31e-2)" "unprognostic (2.52e-4)" 1.2 1.2 2.6 0.2 1.7 0.0 0.9 2.2 2.6 1.6 0.1 0.7 0.0 1.4 0.9 0.2 1.2 0.9 3.7 2.5 1.8 0.5 0.6 0.9 0.0 3.8 2.9 2.5 0.9 0.6 1.2 1.7 2.2 0.7 0.2 1.8 0.7 0.8 0.8 0.5 0.2 0.9 3.4 0.2 0.4 1.5 2.9 0.2 0.8 0.9 0.1 0.8 0.9 2.5 0.0 0.0 7.1 0.0 0.0 0.9 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.0 5.7 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 1.7 2.2 2.6 2.5 1.8 3.8 2.9 2.2 3.4 2.9 2.5 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.1 0.5 1.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 1.9 0.9 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 1.6 0.9 0.1 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 PCDHGA4 PCDH-GAMMA-A4 ENSG00000262576 "Protocadherin gamma subfamily A, 4" Q9Y5G9 5 141355021-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.0;Skeletal myocytes: 1.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 7.4;BJ: 4.3;HSkMC: 4.3;HUVEC TERT2: 4.3;U-87 MG: 6.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.27e-2)" "unprognostic (4.55e-3)" "unprognostic (2.00e-2)" "unprognostic (6.54e-4)" "unprognostic (1.87e-2)" "unprognostic (1.06e-2)" "unprognostic (1.02e-1)" "unprognostic (1.20e-2)" "unprognostic (5.62e-2)" "unprognostic (3.76e-1)" "unprognostic (6.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.94e-2)" "unprognostic (1.30e-2)" "unprognostic (2.30e-2)" "unprognostic (1.65e-1)" "unprognostic (2.31e-4)" 1.7 1.3 1.6 0.4 1.8 0.0 0.9 3.7 1.7 1.3 0.0 0.9 0.2 1.6 0.8 0.4 0.9 0.8 1.5 2.9 1.5 0.4 0.3 1.0 0.1 2.1 2.4 1.6 2.1 2.3 1.0 0.8 1.7 1.1 0.3 1.5 0.8 1.1 0.7 0.5 0.3 1.5 2.0 0.3 0.4 0.7 2.1 0.2 0.7 1.0 0.1 0.7 0.8 2.5 0.0 0.1 0.8 0.4 3.3 7.4 0.0 4.3 3.4 0.2 0.8 0.0 0.1 0.7 1.4 3.7 1.3 0.0 0.1 0.1 0.4 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.3 4.3 0.1 0.0 0.0 2.6 4.3 0.0 0.1 0.2 1.8 0.6 0.2 0.2 0.1 0.0 0.2 0.3 1.2 0.1 0.2 0.0 0.6 1.3 0.2 0.2 0.9 0.3 1.6 0.0 2.8 1.8 0.5 2.4 0.3 0.1 0.2 0.1 6.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.8 3.7 1.7 2.9 1.5 2.1 2.4 1.7 2.0 2.1 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 PCDHGA5 "CDH-GAMMA-A5, ME3, PCDH-GAMMA-A5" ENSG00000253485 "Protocadherin gamma subfamily A, 5" Q9Y5G8 5 141364232-141512979 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 4.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.5;Endometrial stromal cells: 9.2;Horizontal cells: 10.1;Sertoli cells: 6.6;Skeletal myocytes: 5.7" "Cancer enhanced" "Detected in single" "prostate cancer: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 15.8;ASC TERT1: 6.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.61e-2)" "unprognostic (1.04e-2)" "unprognostic (5.28e-2)" "unprognostic (4.83e-1)" "unprognostic (6.60e-3)" "unprognostic (5.71e-2)" "unprognostic (8.46e-2)" "unprognostic (6.53e-3)" "unprognostic (4.07e-1)" "unprognostic (9.40e-2)" "unprognostic (1.38e-1)" "unprognostic (1.05e-1)" "unprognostic (1.12e-1)" "unprognostic (5.90e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (8.38e-4)" 1.0 0.6 1.0 0.3 1.6 0.1 1.2 4.9 1.1 2.5 0.0 1.1 0.1 2.0 0.6 0.8 1.4 1.1 1.9 1.2 1.2 0.3 0.2 1.1 0.2 2.2 2.1 2.0 0.6 0.6 0.9 0.6 1.0 1.4 0.3 1.2 0.8 0.9 0.6 0.7 0.4 1.0 1.2 0.2 0.5 0.3 1.2 0.3 0.5 0.7 0.1 1.0 1.3 2.0 0.0 0.4 0.2 0.1 15.8 6.2 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.8 0.3 0.3 0.8 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.1 0.1 0.1 0.0 1.5 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.5 0.6 0.3 0.5 0.6 0.1 0.0 0.3 0.8 0.6 0.1 0.0 0.0 0.2 0.2 0.0 0.2 0.3 0.2 1.4 0.0 0.9 0.5 0.1 0.9 0.6 0.1 0.9 0.1 0.3 0.1 0.7 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.2 0.0 0.1 0.0 0.0 1.0 1.6 4.9 1.1 1.2 1.2 2.2 2.1 1.0 1.2 1.2 2.0 1.8 0.0 1.1 0.0 0.2 0.1 0.8 0.1 0.6 11.5 0.3 0.4 2.6 0.0 0.7 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.1 0.4 9.2 1.9 0.0 0.0 0.0 0.2 0.0 4.0 0.0 0.2 1.3 0.6 1.4 0.3 0.1 10.1 0.0 0.0 0.0 0.3 0.0 0.0 3.7 0.4 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.2 0.0 1.9 0.0 0.5 0.0 0.1 0.1 1.3 6.6 5.7 1.7 0.0 0.3 0.3 0.0 0.0 0.6 0.9 0.0 0.4 PCDHGA6 PCDH-GAMMA-A6 ENSG00000253731 "Protocadherin gamma subfamily A, 6" Q9Y5G7 5 141373891-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 10.6;Cardiomyocytes: 5.0;Endometrial stromal cells: 4.6;Hepatic stellate cells: 3.6;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SCLC-21H: 9.6;T-47d: 5.6;WM-115: 12.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (4.49e-2)" "unprognostic (8.91e-3)" "unprognostic (5.45e-2)" "unprognostic (1.43e-1)" "unprognostic (1.15e-1)" "unprognostic (1.49e-2)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" "unprognostic (1.25e-1)" "unprognostic (2.07e-2)" "unprognostic (3.86e-3)" "unprognostic (2.02e-2)" "unprognostic (5.26e-2)" "unprognostic (7.44e-2)" "unprognostic (5.21e-2)" "unprognostic (1.11e-1)" "unprognostic (4.19e-3)" 1.4 1.1 1.6 0.7 1.8 0.1 1.3 7.2 1.6 2.7 0.0 2.0 0.2 3.2 1.4 0.8 2.0 1.1 2.7 1.7 1.8 0.8 0.5 1.5 0.4 1.8 1.7 3.5 1.2 1.1 1.8 2.3 0.9 1.2 0.4 2.0 1.5 1.6 0.9 1.5 0.8 2.0 0.8 0.9 0.7 0.8 2.0 0.5 1.2 1.0 0.4 1.6 1.5 1.9 0.0 0.3 2.7 0.4 1.3 4.7 0.1 2.1 0.7 1.1 1.1 0.0 0.1 2.0 2.6 3.3 1.0 0.4 0.1 0.4 0.7 0.0 0.2 0.0 0.3 0.2 0.7 0.1 0.1 4.9 0.3 0.2 0.1 1.0 1.6 0.1 0.2 1.1 0.3 0.4 0.7 1.7 0.3 0.0 0.1 1.4 0.4 0.0 0.3 0.1 9.6 0.7 0.1 0.3 0.6 0.6 5.6 0.1 4.8 0.7 0.3 0.7 0.7 0.4 1.7 0.4 0.8 0.7 12.2 0.4 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.5 0.1 0.0 0.1 0.0 0.0 1.6 1.8 7.2 1.6 1.7 1.8 1.8 1.7 0.9 0.8 2.0 1.9 2.8 0.0 2.2 0.0 0.4 0.0 0.8 0.0 0.0 10.6 0.3 1.0 5.0 1.5 0.6 0.0 0.0 0.1 0.3 0.0 0.0 0.4 0.5 0.4 4.6 1.8 0.0 0.4 0.0 1.5 0.1 2.2 0.0 0.4 0.0 0.6 3.6 0.7 0.1 1.7 0.0 0.2 0.0 0.3 0.0 0.3 1.2 0.5 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.1 2.2 1.6 0.4 0.0 0.3 0.7 0.9 0.0 5.2 1.9 0.3 0.3 0.5 0.0 0.3 0.2 0.5 0.2 0.2 PCDHGA7 PCDH-GAMMA-A7 ENSG00000253537 "Protocadherin gamma subfamily A, 7" Q9Y5G6 5 141382739-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.3;Cardiomyocytes: 1.6;Endometrial stromal cells: 2.2;Skeletal myocytes: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 11.3;BJ hTERT+: 20.8;hTERT-RPE1: 10.9;SH-SY5Y: 18.6;T-47d: 8.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.00e-2)" "unprognostic (4.73e-3)" "unprognostic (1.42e-1)" "unprognostic (7.49e-2)" "unprognostic (2.10e-1)" "unprognostic (6.85e-2)" "unprognostic (2.61e-1)" "unprognostic (1.50e-1)" "unprognostic (1.85e-1)" "unprognostic (5.78e-2)" "unprognostic (3.72e-2)" "unprognostic (1.66e-1)" "unprognostic (3.56e-1)" "unprognostic (4.21e-3)" "unprognostic (6.30e-2)" "unprognostic (4.99e-2)" "unprognostic (1.42e-3)" 0.5 0.4 1.0 0.2 0.9 0.0 0.6 5.9 1.0 1.2 0.0 1.1 0.1 1.3 1.1 0.5 1.0 0.4 1.5 1.1 0.6 0.6 0.4 0.7 0.1 1.5 1.2 1.5 0.7 2.2 0.8 1.3 0.9 0.9 0.3 1.6 0.8 0.8 0.7 1.0 0.4 0.8 1.0 0.4 0.3 0.5 1.3 0.2 1.9 0.5 0.1 0.9 0.7 1.5 0.0 1.6 2.3 0.0 6.6 11.3 0.0 3.3 20.8 4.2 6.1 0.0 0.0 0.5 5.2 0.7 0.2 0.2 0.0 0.1 3.4 0.0 0.3 0.0 0.4 0.2 1.1 0.0 0.0 5.0 0.1 0.0 0.7 10.9 1.7 0.0 0.0 0.1 0.1 0.1 0.6 0.3 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.4 18.6 0.0 0.1 0.1 3.7 8.1 0.0 6.7 0.1 0.1 3.1 0.1 0.1 1.9 0.0 0.5 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.9 5.9 1.0 1.1 0.6 1.5 1.2 0.9 1.0 1.3 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 4.3 0.3 0.3 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 2.2 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.6 0.0 2.8 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.3 PCDHGA8 "KIAA0327, PCDH-GAMMA-A8" ENSG00000253767 "Protocadherin gamma subfamily A, 8" Q9Y5G5 5 141390157-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in single" 7 "brain: 3.9" "Cell type enhanced" "Detected in some" "Bipolar cells: 11.4;Cardiomyocytes: 3.5;Horizontal cells: 3.3;Skeletal myocytes: 5.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.28e-2)" "unprognostic (2.27e-2)" "unprognostic (4.86e-2)" "unprognostic (3.38e-2)" "unprognostic (2.80e-1)" "unprognostic (4.10e-2)" "unprognostic (7.68e-2)" "unprognostic (2.30e-2)" "unprognostic (1.83e-2)" "unprognostic (2.23e-1)" "unprognostic (1.24e-1)" "unprognostic (1.35e-2)" "unprognostic (1.49e-3)" "unprognostic (7.59e-2)" "unprognostic (3.92e-2)" "unprognostic (3.38e-1)" "unprognostic (1.99e-3)" 0.1 0.1 0.6 0.1 0.6 0.4 0.1 3.9 0.8 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.5 0.8 0.5 0.0 0.1 0.1 0.1 1.1 0.7 0.3 0.1 0.0 0.2 0.2 0.7 0.1 0.1 0.5 0.1 0.0 0.3 0.3 0.1 0.1 0.3 0.1 0.1 0.1 0.9 0.1 0.4 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.3 0.1 0.2 0.6 0.1 0.6 0.4 0.4 0.1 0.0 0.1 0.3 0.2 0.4 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.6 0.2 0.4 0.6 0.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.6 0.6 3.9 0.8 0.8 0.5 1.1 0.7 0.7 0.3 0.9 1.2 1.2 0.0 0.6 0.0 0.1 0.0 0.9 0.0 0.0 11.4 0.3 0.3 3.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.6 0.1 2.1 1.2 0.0 0.0 0.0 0.6 0.0 1.1 0.0 0.2 0.0 0.3 0.4 0.7 0.1 3.3 0.0 0.0 0.0 0.3 0.0 0.0 2.1 0.2 0.0 0.0 0.0 1.3 1.0 0.0 0.0 0.1 0.1 1.5 0.0 0.7 0.0 0.2 0.0 1.7 0.0 5.2 0.9 0.7 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.5 PCDHGA9 PCDH-GAMMA-A9 ENSG00000261934 "Protocadherin gamma subfamily A, 9" Q9Y5G4 5 141402932-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.5;Cardiomyocytes: 1.3;Endometrial stromal cells: 1.5;Horizontal cells: 3.3;Skeletal myocytes: 2.3" "Cancer enhanced" "Detected in some" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 3.6;HSkMC: 4.0;hTERT-RPE1: 16.9;TIME: 4.6;U-87 MG: 5.1" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.98e-2)" "unprognostic (7.47e-3)" "unprognostic (9.86e-3)" "unprognostic (2.22e-1)" "unprognostic (4.68e-2)" "unprognostic (4.96e-2)" "unprognostic (1.61e-1)" "unprognostic (2.15e-1)" "unprognostic (2.39e-1)" "unprognostic (1.87e-3)" "unprognostic (2.26e-1)" "unprognostic (1.79e-1)" "unprognostic (4.48e-3)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (2.71e-1)" "unprognostic (1.83e-2)" 1.8 1.6 3.3 0.7 3.5 0.1 1.3 6.6 3.2 2.0 0.4 1.2 0.5 2.5 1.1 1.4 1.9 2.0 1.1 3.7 2.6 0.8 0.4 1.5 0.5 3.6 3.4 2.8 0.8 1.1 0.9 1.0 3.8 1.5 0.7 4.4 1.1 2.2 0.8 1.7 0.6 1.8 3.7 1.1 0.8 0.4 3.6 0.5 1.4 1.2 0.7 1.2 1.4 5.7 0.0 0.1 0.6 1.6 0.1 0.2 0.2 0.7 0.0 0.6 0.6 0.2 0.4 1.3 3.6 2.0 0.3 0.1 0.1 0.2 0.7 0.0 0.3 0.0 0.1 0.0 1.1 0.0 0.2 4.0 0.1 0.4 0.3 16.9 1.0 0.0 0.1 0.2 0.3 0.3 0.1 0.5 0.2 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.4 1.1 0.4 0.1 0.5 0.4 0.9 0.4 4.6 0.3 0.3 0.1 2.5 0.2 0.0 0.0 5.1 0.1 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 3.5 6.6 3.2 3.7 2.6 3.6 3.4 3.8 3.7 3.6 5.7 0.6 0.0 0.0 0.0 0.1 0.3 0.2 0.3 0.6 4.5 0.2 0.3 1.3 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.5 0.9 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.4 0.2 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.0 2.3 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.0 0.1 PCDHGB1 PCDH-GAMMA-B1 ENSG00000254221 "Protocadherin gamma subfamily B, 1" Q9Y5G3 5 141350102-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.5" "Cell type enhanced" "Detected in some" "Early spermatids: 5.7;Late spermatids: 7.6;Melanocytes: 1.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.9;ASC TERT1: 6.6;hTERT-RPE1: 7.1;T-47d: 8.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076182" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Focal adhesion sites,Midbody" Yes No "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Vesicles, Plasma membrane" "Nucleoplasm, Focal adhesion sites, Midbody" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076182: AB_2686783" "unprognostic (1.53e-2)" "unprognostic (1.94e-3)" "unprognostic (3.21e-1)" "unprognostic (4.38e-3)" "unprognostic (2.98e-1)" "unprognostic (8.36e-3)" "unprognostic (2.37e-1)" "unprognostic (9.57e-2)" "unprognostic (8.57e-2)" "unprognostic (1.06e-1)" "unprognostic (3.44e-2)" "unprognostic (4.78e-2)" "unprognostic (6.33e-2)" "unprognostic (3.15e-2)" "unprognostic (8.75e-2)" "unprognostic (1.93e-1)" "unprognostic (7.63e-3)" 0.6 0.7 1.8 0.1 1.2 0.0 0.5 2.1 1.6 0.6 0.0 0.3 0.0 1.2 0.4 0.3 0.4 0.5 0.5 2.9 1.6 0.4 0.1 0.6 0.0 1.9 3.3 1.4 0.8 2.3 1.0 0.2 2.4 0.6 0.1 1.6 0.3 0.9 0.2 0.2 0.1 0.9 2.4 0.1 0.1 0.4 1.8 0.0 0.6 0.3 0.0 0.3 0.3 3.5 0.1 1.9 1.6 0.0 12.9 6.6 0.1 1.2 3.2 0.5 0.7 0.2 0.5 0.5 4.2 0.5 3.1 0.6 0.3 0.2 0.4 0.0 0.8 0.0 0.2 1.2 0.2 0.0 0.0 1.0 0.0 0.0 0.0 7.1 0.1 0.0 0.2 0.2 3.0 1.7 0.4 0.3 0.2 0.0 0.0 0.0 2.4 0.1 0.0 0.0 1.0 0.7 0.0 0.8 0.1 1.2 8.6 0.0 1.0 0.2 1.3 1.1 0.0 0.0 2.4 0.3 2.5 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.2 2.1 1.6 2.9 1.6 1.9 3.3 2.4 2.4 1.8 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.7 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 1.8 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGB2 PCDH-GAMMA-B2 ENSG00000253910 "Protocadherin gamma subfamily B, 2" Q9Y5G2 5 141360042-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 2.2;Cardiomyocytes: 1.4;Endometrial stromal cells: 1.0;Fibroblasts: 1.2" "Cancer enriched" "Detected in many" 5 "glioma: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 13.5;ASC TERT1: 9.8;LHCN-M2: 8.2;REH: 7.8" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077526" Uncertain Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane, Cytosol" Nucleoplasm "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077526: AB_2732350" "unprognostic (7.14e-3)" "unprognostic (8.79e-3)" "unprognostic (3.21e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.67e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-4)" "unprognostic (2.68e-1)" "unprognostic (2.64e-1)" "unprognostic (1.78e-1)" "unprognostic (1.05e-1)" "unprognostic (8.46e-3)" "unprognostic (4.59e-2)" "unprognostic (2.57e-1)" "unprognostic (3.06e-2)" "unprognostic (1.29e-1)" "unprognostic (3.36e-4)" 1.5 1.0 2.6 0.6 3.6 0.1 1.1 6.3 2.8 2.1 0.0 1.1 0.2 3.0 0.9 0.9 1.6 1.9 1.8 3.1 3.2 0.7 0.7 1.7 0.3 3.7 3.3 2.8 0.8 1.2 0.9 1.1 3.6 1.3 0.8 1.6 0.8 1.2 0.8 0.8 0.5 1.5 3.0 0.6 0.6 0.5 2.2 0.4 0.7 0.9 0.3 0.9 1.1 5.5 0.1 0.3 2.0 0.2 13.5 9.8 0.1 2.1 2.9 0.6 3.2 0.0 0.3 3.7 1.0 1.7 7.1 0.5 0.4 0.3 1.0 0.0 0.2 0.0 0.3 0.4 0.5 0.2 0.2 2.5 0.5 0.2 0.1 4.7 1.7 0.1 0.2 1.2 8.2 0.5 2.9 0.7 0.1 0.9 0.9 7.8 2.6 0.2 0.2 0.3 1.5 1.6 0.2 0.4 0.4 1.5 3.0 0.2 5.9 2.9 0.6 4.4 3.9 0.2 2.2 0.6 3.1 1.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 3.6 6.3 2.8 3.1 3.2 3.7 3.3 3.6 3.0 2.2 5.5 0.1 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.6 2.2 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 1.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB3 PCDH-GAMMA-B3 ENSG00000262209 "Protocadherin gamma subfamily B, 3" Q9Y5G1 5 141370242-141512975 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.8" "Cell type enhanced" "Detected in single" "Cardiomyocytes: 1.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 10.4;ASC TERT1: 8.4;fHDF/TERT166: 3.5;TIME: 5.5" "HPA008755, HPA010580, HPA035822, HPA035823" Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Vesicles, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA035822: , HPA035823: AB_2674802" "unprognostic (6.93e-3)" "unprognostic (9.10e-4)" "unprognostic (1.35e-1)" "unprognostic (7.05e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" "unprognostic (7.83e-2)" "unprognostic (1.92e-1)" "unprognostic (6.08e-2)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.81e-2)" "unprognostic (3.11e-1)" "unprognostic (3.62e-2)" "unprognostic (3.89e-2)" "unprognostic (2.80e-3)" 0.7 0.3 0.4 0.2 0.8 0.0 0.5 3.8 0.8 0.8 0.0 0.8 0.0 1.0 0.6 0.3 0.7 0.4 1.2 0.9 0.5 0.3 0.2 0.5 0.2 1.3 1.4 1.2 0.7 1.1 0.7 0.4 0.6 0.4 0.3 0.8 0.8 0.4 0.5 0.6 0.3 0.7 0.6 0.4 0.4 0.4 0.8 0.3 0.6 0.5 0.2 0.6 0.6 1.4 0.0 0.6 0.4 0.3 10.4 8.4 0.2 1.2 2.0 0.7 0.8 0.0 0.0 1.8 0.3 3.5 0.6 0.5 0.0 0.2 0.5 0.0 0.2 0.0 0.2 0.1 0.4 0.1 0.0 2.1 0.4 0.2 0.1 0.2 1.0 0.0 0.2 0.8 0.2 0.4 0.6 0.9 0.1 0.0 0.1 1.5 0.6 0.0 0.2 0.1 2.4 0.5 0.0 0.0 0.2 0.3 0.6 0.0 5.5 0.5 0.1 0.5 0.6 0.2 1.8 0.2 0.4 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 3.8 0.8 0.9 0.5 1.3 1.4 0.6 0.6 0.8 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHGB4 "CDH20, FIB2, PCDH-GAMMA-B4" ENSG00000253953 "Protocadherin gamma subfamily B, 4" Q9UN71 5 141387698-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 1.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 43.3;SuSa: 15.5;TIME: 22.7" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (3.33e-1)" "unprognostic (1.83e-3)" "unprognostic (2.91e-1)" "unprognostic (1.18e-1)" "unprognostic (1.23e-2)" "unprognostic (9.25e-3)" "unprognostic (2.20e-1)" "unprognostic (1.25e-2)" "unprognostic (1.99e-1)" "unprognostic (1.74e-1)" "unprognostic (1.29e-1)" "unprognostic (3.78e-2)" "unprognostic (2.31e-2)" "unprognostic (2.70e-2)" "unprognostic (2.62e-1)" "unprognostic (1.13e-1)" "unprognostic (3.27e-2)" 1.3 1.1 1.3 0.4 1.5 0.0 0.9 4.4 1.4 1.5 1.8 1.1 0.2 1.6 1.5 0.7 1.3 0.5 1.5 2.0 3.2 1.4 1.6 1.1 0.1 2.0 2.0 2.4 1.0 1.9 1.2 3.0 1.5 1.2 0.4 1.4 1.6 1.4 1.0 1.7 0.5 1.0 1.4 0.4 0.4 0.5 2.5 0.7 1.7 0.8 0.2 1.0 1.1 1.5 0.0 1.1 11.1 0.1 6.9 8.5 1.3 10.8 43.3 4.4 3.0 0.0 0.0 0.4 8.3 0.3 0.2 3.3 0.0 0.0 4.6 0.0 0.0 0.0 0.2 2.4 2.8 0.0 0.0 8.4 0.1 4.1 0.0 0.1 6.7 0.0 0.4 0.1 0.0 0.0 1.1 0.2 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.4 0.0 15.5 5.6 4.2 22.7 6.0 1.8 0.3 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 1.5 4.4 1.4 2.0 3.2 2.0 2.0 1.5 1.4 2.5 1.5 0.2 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.6 1.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.1 PCDHGB5 PCDH-GAMMA-B5 ENSG00000276547 "Protocadherin gamma subfamily B, 5" Q9Y5G0 5 141397987-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 1.2;Bipolar cells: 1.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 66.3;ASC TERT1: 49.6;BJ hTERT+ SV40 Large T+: 29.2;BJ hTERT+ SV40 Large T+ RasG12V: 32.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (2.71e-3)" "unprognostic (1.95e-2)" "unprognostic (1.09e-1)" "unprognostic (4.14e-2)" "unprognostic (2.35e-1)" "unprognostic (1.20e-1)" "unprognostic (3.64e-2)" "unprognostic (2.34e-2)" "unprognostic (1.54e-1)" "unprognostic (1.23e-1)" "unprognostic (1.90e-1)" "unprognostic (2.29e-1)" "unprognostic (1.69e-4)" "unprognostic (9.63e-3)" "unprognostic (3.21e-1)" "unprognostic (1.12e-1)" "unprognostic (8.25e-4)" 2.8 2.7 3.6 1.1 3.6 0.0 1.8 5.8 3.1 2.0 3.3 1.7 0.7 3.1 2.0 1.9 2.8 1.6 2.9 3.9 6.4 2.2 2.1 2.7 0.4 5.1 4.7 5.7 3.8 20.3 1.7 4.8 5.4 3.0 0.9 3.1 4.7 3.9 2.1 3.8 0.8 2.8 5.3 1.3 1.5 1.9 4.9 1.3 4.5 1.9 0.8 1.9 2.1 6.1 0.0 2.4 0.3 0.0 66.3 49.6 1.3 18.3 0.0 29.2 32.5 2.9 10.0 10.6 23.4 20.5 0.0 13.9 0.0 7.6 16.4 0.0 3.1 0.0 0.0 0.1 6.9 0.0 6.5 17.6 1.5 1.7 9.4 12.6 9.0 0.0 0.2 0.0 1.0 8.1 0.0 1.5 0.4 0.0 0.0 0.0 0.0 0.0 1.6 5.5 0.0 0.1 0.0 0.1 0.0 2.0 19.1 0.1 9.2 0.0 2.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 3.6 5.8 3.1 3.9 6.4 5.1 4.7 5.4 5.3 4.9 6.1 0.5 0.0 0.0 0.0 0.2 0.0 0.3 0.0 1.2 1.5 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.6 0.6 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.0 0.8 0.5 0.0 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.1 PCDHGB6 PCDH-GAMMA-B6 ENSG00000253305 "Protocadherin gamma subfamily B, 6" Q9Y5F9 5 141408021-141512979 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 6.9;Cone photoreceptor cells: 6.2;Horizontal cells: 10.1;Skeletal myocytes: 5.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 16.0;EFO-21: 5.4;HSkMC: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.11e-1)" "unprognostic (4.18e-2)" "unprognostic (2.63e-1)" "unprognostic (7.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.90e-1)" "unprognostic (1.18e-1)" "unprognostic (1.85e-2)" "unprognostic (3.51e-1)" "unprognostic (1.11e-1)" "unprognostic (4.77e-2)" "unprognostic (9.89e-2)" "unprognostic (1.43e-1)" "unprognostic (2.17e-2)" "unprognostic (3.27e-1)" "unprognostic (1.21e-2)" "unprognostic (7.71e-4)" 3.1 3.1 3.0 0.9 3.6 0.4 2.2 5.0 2.4 2.9 2.9 2.4 0.5 3.2 2.0 1.2 2.9 1.7 2.4 2.5 3.5 1.1 1.3 2.0 0.7 3.6 3.5 6.0 1.2 2.8 1.8 3.1 3.2 1.4 0.7 2.8 2.2 2.4 2.9 2.1 1.0 1.9 3.3 1.5 1.1 0.6 3.7 0.6 2.6 1.5 0.6 1.8 2.3 3.9 0.0 0.1 16.0 0.1 0.5 0.6 0.8 1.4 0.0 0.4 0.9 0.2 0.2 1.4 5.4 0.9 0.2 0.3 0.0 0.3 1.0 0.0 0.3 0.0 0.2 0.1 1.3 0.1 0.1 3.6 1.8 0.8 0.1 0.1 0.5 0.3 0.1 0.2 0.1 0.3 0.1 1.1 0.6 0.0 0.0 0.2 0.0 0.1 2.5 0.2 0.2 0.3 0.0 0.1 0.1 0.4 1.2 0.3 2.6 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.7 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 3.0 3.6 5.0 2.4 2.5 3.5 3.6 3.5 3.2 3.3 3.7 3.9 3.6 3.2 0.5 0.0 1.0 0.0 1.5 0.0 0.0 6.9 0.6 0.4 3.9 0.0 1.3 0.0 6.2 0.2 0.6 0.4 0.0 0.7 0.0 0.6 3.8 2.6 0.0 0.0 0.0 1.2 0.1 3.3 1.1 0.5 0.0 0.4 1.4 0.7 0.3 10.1 0.0 0.4 0.0 0.0 0.0 0.2 1.8 0.2 0.0 0.0 0.1 2.7 0.0 0.0 0.0 2.0 0.1 1.2 1.5 0.8 0.1 0.3 0.7 2.5 0.0 5.2 3.2 0.2 0.5 0.3 0.1 0.1 0.7 0.8 0.4 0.8 PCDHGB7 "ME6, PCDH-GAMMA-B7" ENSG00000254122 "Protocadherin gamma subfamily B, 7" Q9Y5F8 5 141417645-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 7.9;Fibroblasts: 3.4;Horizontal cells: 3.3;Skeletal myocytes: 5.9" "Cancer enhanced" "Detected in many" "glioma: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "AN3-CA: 86.7;HSkMC: 26.7;hTERT-RPE1: 72.4" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (1.22e-2)" "unprognostic (2.55e-2)" "unprognostic (7.39e-3)" "unprognostic (2.95e-1)" "unprognostic (1.49e-1)" "unprognostic (3.34e-1)" "unprognostic (1.98e-1)" "unprognostic (1.25e-1)" "unprognostic (8.40e-2)" "unprognostic (4.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.88e-2)" "unprognostic (3.05e-1)" "unprognostic (2.22e-2)" "unprognostic (1.44e-1)" "unprognostic (1.91e-1)" "unprognostic (5.68e-2)" 5.2 4.6 4.6 1.8 4.7 0.1 4.2 10.8 3.5 4.9 5.0 5.0 0.9 5.7 2.2 3.0 4.4 4.4 4.3 4.5 7.0 2.4 1.5 5.8 1.2 6.0 6.0 8.1 1.7 4.3 2.2 5.5 5.3 3.8 1.7 5.8 3.7 5.5 3.0 3.3 2.1 5.1 7.7 2.7 2.4 1.9 5.0 1.5 4.0 4.1 0.9 3.3 3.8 7.3 0.0 0.0 2.9 86.7 1.9 0.3 0.9 5.7 0.7 2.1 4.3 0.1 5.3 0.7 4.6 11.7 0.8 1.4 0.2 1.0 2.0 0.1 0.6 0.0 0.2 0.0 6.4 0.5 0.1 26.7 0.7 1.7 0.9 72.4 4.6 0.2 0.0 0.0 0.3 0.0 0.0 0.1 1.0 0.0 0.6 10.1 1.9 0.0 0.2 0.0 9.3 12.8 0.2 0.0 0.0 1.0 1.0 0.9 11.5 10.3 0.2 0.9 0.1 0.1 0.2 0.0 1.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.6 4.7 10.8 3.5 4.5 7.0 6.0 6.0 5.3 7.7 5.0 7.3 2.2 3.2 1.3 0.0 0.3 0.4 0.8 0.0 0.0 7.9 0.3 0.5 1.4 0.0 0.1 0.0 2.1 0.1 0.0 0.0 0.0 0.2 0.1 0.4 2.1 2.2 0.0 0.0 0.0 0.5 0.1 3.4 0.0 0.3 1.3 0.5 0.4 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.4 0.0 1.2 0.2 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.1 0.0 1.9 0.1 0.4 0.0 0.3 0.0 0.7 0.0 5.9 2.2 0.0 0.1 0.5 0.4 0.0 0.0 1.2 0.1 0.2 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PCDHGC4 PCDH-GAMMA-C4 ENSG00000242419 "Protocadherin gamma subfamily C, 4" Q9Y5F7 5 141484997-141512979 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 31.4" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.1;Horizontal cells: 3.3" "Cancer enriched" "Detected in single" 10 "glioma: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 9.1;SCLC-21H: 7.3;SH-SY5Y: 14.2;SuSa: 10.0" "Low region specificity" "Detected in all" "HPA008755, HPA010580" Uncertain Uncertain "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401" "unprognostic (6.05e-2)" "unprognostic (1.26e-3)" "unprognostic (4.78e-2)" "unprognostic (1.41e-1)" "unprognostic (3.44e-1)" "unprognostic (7.84e-2)" "unprognostic (9.48e-2)" "unprognostic (3.27e-1)" "unprognostic (4.55e-1)" "unprognostic (1.17e-1)" "unprognostic (8.72e-3)" "unprognostic (4.73e-3)" "unprognostic (2.20e-4)" "unprognostic (8.78e-2)" "unprognostic (3.06e-2)" "unprognostic (1.47e-1)" "unprognostic (2.75e-2)" 0.2 1.1 17.3 0.1 12.2 0.0 0.2 19.3 14.6 0.3 0.1 0.6 0.0 0.4 0.2 0.2 0.3 0.2 2.2 12.7 13.9 0.1 0.1 0.4 0.1 12.9 21.9 0.3 0.3 0.0 1.1 0.1 10.3 0.2 0.1 6.6 0.3 0.1 0.7 0.5 0.1 0.2 22.4 0.1 0.2 0.9 14.3 0.0 0.1 0.3 0.2 0.2 0.3 31.4 0.0 0.0 0.9 0.2 0.2 0.7 0.4 0.1 0.1 0.1 0.2 0.0 0.0 0.2 0.8 0.9 0.1 0.1 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.8 0.0 1.3 0.0 0.0 9.1 0.5 0.0 0.0 0.1 7.3 14.2 0.1 0.0 0.1 10.0 0.1 0.3 0.1 0.8 0.1 0.2 0.6 0.2 0.0 0.2 0.6 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 12.2 19.3 14.6 12.7 13.9 12.9 21.9 10.3 22.4 14.3 31.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 PCDHGC5 PCDH-GAMMA-C5 ENSG00000240764 "Protocadherin gamma subfamily C, 5" Q9Y5F6 5 141489081-141512975 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 28.4" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "glioma: 3.1;head and neck cancer: 0.8" "Region enhanced" "Detected in many" "hippocampal formation: 28.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTERT-RPE1: 4.6;SuSa: 7.4;U-138 MG: 14.4;U-251 MG: 6.5;U-87 MG: 8.9" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA076140" Supported Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Vesicles, Plasma membrane" "Nucleoplasm, Cytosol" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA076140: " "unprognostic (2.86e-3)" "unprognostic (7.63e-4)" "unprognostic (2.00e-1)" "unprognostic (3.52e-3)" "unprognostic (5.42e-2)" "unprognostic (1.14e-1)" "unprognostic (5.65e-2)" "unprognostic (2.38e-2)" "unprognostic (2.14e-1)" "unprognostic (3.16e-2)" "unprognostic (3.90e-1)" "unprognostic (1.66e-2)" "unprognostic (1.01e-9)" "unprognostic (6.87e-3)" "unprognostic (3.89e-2)" "unprognostic (3.13e-1)" "unprognostic (3.77e-3)" 0.3 0.5 5.6 0.1 8.6 0.0 0.3 0.0 11.7 0.8 0.0 1.3 0.0 1.2 0.2 0.3 0.7 0.2 5.3 28.4 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 1.2 0.1 0.0 0.5 0.0 1.2 0.4 0.5 1.2 0.5 0.2 0.7 0.0 0.1 0.3 0.6 0.3 0.1 0.2 0.2 0.0 0.5 0.6 0.0 0.0 0.0 0.3 0.3 0.3 1.5 0.1 0.8 0.5 0.4 0.5 0.0 0.0 0.4 1.4 2.2 0.1 0.1 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 3.2 0.0 4.6 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.8 0.8 0.2 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 7.4 0.1 0.2 0.1 14.4 0.2 0.2 6.5 0.0 0.0 0.0 8.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.6 0.0 11.7 28.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 655.4;Inhibitory neurons: 746.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 28 "REH: 263.3;U-2 OS: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 1.8 4.2 4.0 0.2 5.5 0.0 2.4 25.6 22.4 1.5 0.0 2.1 1.5 0.3 3.8 2.3 1.0 0.9 1.4 7.8 1.7 4.4 0.1 0.8 0.1 0.0 0.0 0.8 3.9 4.4 11.1 0.3 0.0 2.5 1.7 21.7 2.5 2.5 0.1 2.0 1.7 0.1 0.0 0.5 1.5 3.7 1.3 1.2 4.6 0.1 0.2 0.6 2.6 4.2 1.2 1.6 1.9 0.0 0.8 0.1 0.0 0.7 0.7 0.5 1.0 0.3 0.7 0.0 0.0 0.8 7.7 0.6 5.7 2.4 2.4 0.3 0.8 0.0 1.2 0.1 0.0 0.8 0.2 0.4 1.8 0.0 9.6 0.5 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.0 2.0 1.0 4.7 263.3 4.2 0.0 1.9 0.9 4.9 3.4 0.2 2.7 0.6 1.2 3.4 0.6 0.0 0.0 284.5 1.2 0.6 0.2 0.0 0.5 1.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.5 25.6 22.4 7.8 1.7 0.0 0.0 0.0 0.0 1.3 4.2 0.6 9.6 17.9 40.5 0.0 2.5 9.0 3.2 13.6 121.9 11.0 9.7 31.2 22.8 12.6 1.8 131.3 1.9 0.0 22.9 7.9 6.4 13.0 7.4 6.7 2.5 60.1 0.0 655.4 4.9 0.4 2.4 20.4 13.5 0.0 24.2 0.0 0.2 1.7 85.8 746.4 15.0 2.0 0.0 0.0 7.9 2.8 0.4 0.0 50.6 0.0 16.2 0.0 73.9 73.7 2.5 21.9 6.4 0.0 3.9 13.5 23.0 7.7 86.9 0.0 0.3 3.2 5.0 19.5 19.3 3.4 0.7 0.3 37.5 9.3 6.0 PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA025696: AB_1855077, HPA061444: AB_2684519" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.73e-3)" "unprognostic (2.58e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (8.38e-2)" "unprognostic (3.73e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (3.11e-3)" "unprognostic (3.11e-3)" 36.5 35.2 18.2 23.3 20.2 16.8 38.2 25.2 21.9 33.8 23.2 38.8 25.9 35.3 47.5 28.0 30.8 29.0 35.5 16.4 19.9 38.3 30.4 28.3 28.8 19.1 19.2 42.6 73.9 77.9 25.5 26.3 19.9 36.1 25.8 25.4 57.6 32.0 83.4 33.5 26.8 28.3 18.9 46.3 29.5 14.9 18.9 35.1 53.3 67.1 27.3 32.6 31.0 21.6 11.7 5.7 24.3 5.4 34.1 28.4 14.0 13.4 22.8 5.5 9.0 3.1 23.6 12.0 18.0 17.3 8.4 27.2 4.7 15.8 9.3 11.9 8.5 12.6 11.7 8.3 43.9 5.2 12.4 30.4 31.7 6.9 17.4 35.8 24.4 16.0 9.5 36.0 12.0 4.2 24.5 13.7 8.9 16.7 3.0 8.0 4.5 13.8 24.7 21.7 16.2 15.0 10.9 14.8 17.1 18.5 14.2 7.6 22.2 6.8 5.9 8.8 5.2 21.6 15.6 3.9 16.4 11.4 7.0 18.7 8.4 23.2 8.6 11.0 10.4 13.1 11.5 9.4 8.1 13.0 13.5 12.4 29.4 21.6 12.7 14.7 13.2 9.1 18.2 20.2 25.2 21.9 16.4 19.9 19.1 19.2 19.9 18.9 18.9 21.6 98.4 115.4 68.1 78.7 78.1 54.0 66.0 49.7 58.6 80.7 66.7 61.0 92.7 48.6 52.0 84.6 10.4 38.1 80.7 28.7 64.6 32.9 4.7 66.6 63.9 79.3 46.7 51.4 144.7 39.8 37.2 79.2 45.9 92.2 53.0 107.2 76.4 37.1 25.1 58.9 159.7 39.0 61.1 51.8 56.8 10.4 104.1 62.7 71.2 144.3 52.5 120.8 55.6 106.1 122.3 43.8 32.2 120.0 101.8 98.0 45.5 92.8 56.7 24.0 39.5 73.2 68.2 16.4 24.2 38.3 59.2 68.5 62.1 87.6 30.9 94.6 PDAP1 "HASPP28, PAP, PAP1" ENSG00000106244 "PDGFA associated protein 1" Q13442 7 99392048-99408597 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021103, HPA050294, HPA060836" Approved Enhanced "Plasma membrane,Cytosol" NA NA 410000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB021103: AB_10057973, HPA050294: AB_2681077, HPA060836: AB_2684374" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.63e-1)" "unprognostic (3.35e-2)" "unprognostic (1.45e-2)" "unprognostic (3.51e-2)" "unprognostic (1.79e-1)" "unprognostic (3.49e-1)" "unprognostic (2.97e-2)" 25.7 29.6 35.8 22.6 36.2 23.2 24.4 36.5 39.3 26.2 34.1 32.4 17.9 26.9 17.5 37.2 22.6 11.9 40.2 34.4 36.1 28.5 31.3 24.0 18.9 37.3 37.9 25.7 26.6 22.5 21.9 19.2 37.4 26.0 18.0 22.9 26.2 20.9 105.0 27.9 23.3 21.1 37.6 23.8 26.3 19.7 37.0 25.5 24.3 59.7 22.4 29.3 26.4 36.6 96.9 82.4 54.6 71.0 41.5 43.2 34.7 76.7 44.9 61.6 51.8 83.9 47.4 41.3 67.2 74.7 78.4 50.2 66.3 78.4 60.5 59.8 74.4 43.6 80.8 74.1 60.8 80.1 40.5 45.6 58.5 68.1 110.3 56.3 62.7 67.5 103.0 75.6 61.4 200.3 110.4 111.2 68.7 98.1 88.3 50.5 54.3 73.6 63.6 73.0 54.8 110.6 58.0 92.4 43.4 61.3 41.1 42.5 57.6 83.6 91.4 100.8 123.6 71.4 87.5 91.0 67.7 72.2 89.1 13.4 12.1 12.5 15.4 16.6 13.9 15.7 14.2 11.2 10.2 14.9 9.8 13.2 31.6 28.0 15.6 21.1 20.9 6.6 35.8 36.2 36.5 39.3 34.4 36.1 37.3 37.9 37.4 37.6 37.0 36.6 82.9 86.6 94.7 6.2 73.6 62.2 110.6 104.6 57.5 97.4 84.3 76.6 63.6 72.9 86.7 42.3 33.3 213.1 84.7 101.6 168.3 176.1 60.3 91.3 118.6 99.1 117.9 151.7 10.1 171.0 223.0 87.4 59.7 88.3 72.2 83.4 61.8 80.8 114.9 77.4 11.6 116.5 75.3 38.3 63.3 78.3 83.6 66.1 103.2 5.6 102.1 166.4 119.4 8.0 17.4 177.4 92.2 92.2 102.5 184.3 100.0 134.5 96.8 101.0 52.6 85.6 127.2 132.5 123.0 131.9 65.6 184.4 79.5 115.2 114.0 122.5 PDCD7 "ES18, HES18" ENSG00000090470 "Programmed cell death 7" Q8N8D1 15 65117379-65133808 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 176.1;Cone photoreceptor cells: 221.0;Rod photoreceptor cells: 176.3;Spermatocytes: 164.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049388 Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoli "HPA049388: AB_2680741" "unprognostic (7.71e-3)" "unprognostic (3.25e-1)" "unprognostic (4.09e-1)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (1.22e-1)" "unprognostic (6.68e-3)" "unprognostic (2.36e-2)" "unprognostic (3.18e-3)" "unprognostic (8.18e-2)" "unprognostic (3.28e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.29e-2)" "unprognostic (3.42e-2)" "unprognostic (1.44e-1)" "unprognostic (1.62e-2)" 12.0 12.4 13.8 11.9 14.3 10.0 11.9 18.0 18.2 16.2 12.2 15.8 9.9 16.5 12.7 17.8 13.6 8.4 11.4 14.2 13.3 10.3 12.5 10.2 14.5 14.2 13.5 16.8 11.2 11.6 10.9 11.9 14.6 13.0 9.3 10.8 10.0 11.9 13.1 11.1 11.3 13.3 12.0 13.4 11.0 18.9 14.2 15.7 12.5 8.7 15.1 14.8 14.0 16.7 18.2 14.9 24.8 25.7 24.4 34.2 15.0 20.4 22.6 24.7 18.8 18.2 19.7 34.9 21.7 16.5 18.5 33.5 63.9 14.7 17.7 21.3 17.0 33.9 12.8 15.9 22.5 46.6 21.8 20.0 22.0 13.6 25.4 23.7 19.8 25.6 44.0 27.6 21.7 13.9 48.7 33.2 30.1 21.1 13.3 42.7 31.8 39.0 15.2 28.5 20.4 24.3 22.8 19.1 31.3 27.0 15.4 37.7 20.0 25.2 24.6 14.8 31.9 49.1 60.4 24.9 22.7 50.5 13.2 2.1 1.4 0.9 2.0 1.2 1.7 2.3 1.9 1.8 1.3 2.4 2.0 1.9 0.3 3.3 1.2 1.8 1.5 0.7 13.8 14.3 18.0 18.2 14.2 13.3 14.2 13.5 14.6 12.0 14.2 16.7 33.6 0.0 14.3 10.1 46.3 38.0 67.8 6.0 89.4 176.1 33.1 40.9 17.7 21.5 11.1 29.5 221.0 55.3 55.8 17.2 29.4 9.0 5.9 26.8 51.8 36.5 14.4 27.5 31.0 8.2 32.6 38.4 20.4 28.2 19.7 49.0 31.1 19.4 23.6 75.7 32.9 26.9 6.1 23.2 22.8 8.9 58.1 24.7 12.4 9.4 14.5 47.2 45.3 15.1 28.9 7.3 11.6 48.2 37.9 56.8 14.2 22.7 8.5 176.3 46.0 45.5 38.8 164.6 107.3 48.8 39.9 71.4 49.5 60.3 26.1 51.5 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 190.8;Late spermatids: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 36.5;NB-4: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 13.7 5.6 10.9 5.9 12.5 5.4 9.7 3.0 32.3 12.4 0.0 11.0 2.7 9.8 1.4 4.1 7.5 6.6 12.5 11.8 7.9 7.0 2.5 13.0 3.2 21.9 7.1 1.5 12.7 22.2 3.9 6.5 20.8 8.4 4.0 5.3 9.8 4.8 37.9 5.4 6.5 6.2 1.1 8.2 12.9 24.5 13.0 1.6 11.0 16.9 2.6 8.2 8.2 15.7 0.1 2.5 0.5 6.7 18.7 11.1 3.7 5.6 11.1 0.7 1.9 6.0 5.4 2.6 16.1 14.6 0.4 0.6 3.9 0.7 0.4 6.7 5.5 23.7 8.1 6.7 12.3 3.9 36.5 8.3 0.8 6.2 0.0 0.7 5.3 2.1 18.9 5.5 4.0 1.7 2.3 43.3 2.9 6.7 4.7 15.6 3.7 20.3 0.9 1.4 4.2 1.5 0.4 0.2 6.2 1.0 0.8 7.8 11.2 8.3 10.5 5.7 3.7 10.9 0.9 12.4 3.5 0.3 6.7 4.1 1.7 3.4 0.8 2.5 0.4 0.1 0.3 1.1 2.0 0.0 0.0 0.4 0.1 3.0 2.7 0.1 0.7 1.1 10.9 12.5 3.0 32.3 11.8 7.9 21.9 7.1 20.8 1.1 13.0 15.7 9.4 3.2 11.6 6.2 10.8 10.1 2.6 2.5 1.8 25.6 6.4 4.3 7.7 8.6 5.5 9.2 0.0 0.5 58.9 7.1 0.0 3.1 48.9 2.1 20.7 8.6 0.0 1.7 39.4 12.9 4.8 12.1 7.1 3.6 31.8 0.3 10.4 0.9 10.2 55.5 43.5 5.1 6.1 22.1 190.8 197.0 17.4 53.9 14.2 12.2 15.4 1.2 22.6 12.5 1.5 12.3 3.8 18.0 27.0 3.0 0.1 0.2 6.9 3.6 6.6 9.0 10.2 8.6 8.5 0.5 8.1 0.4 37.0 1.0 6.8 1.3 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;skeletal muscle: 70.4" "Cell type enhanced" "Detected in many" "Astrocytes: 619.3;Excitatory neurons: 2969.7;Inhibitory neurons: 1116.9;Oligodendrocyte precursor cells: 848.0;Oligodendrocytes: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 57.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 57.9" "Cell line enhanced" "Detected in many" "A549: 62.2;AN3-CA: 70.4;HeLa: 104.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favorable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.9 1.3 3.3 9.8 9.9 74.9 4.6 0.0 11.3 5.3 0.0 21.0 5.5 7.4 18.4 13.7 7.3 9.1 15.7 4.4 4.2 17.2 2.8 13.3 5.3 7.0 2.0 3.0 3.7 5.5 6.7 16.6 1.2 19.9 15.0 21.4 7.4 21.2 70.4 4.5 7.0 15.3 0.8 4.0 10.3 3.4 3.8 8.6 7.4 34.4 5.6 22.0 8.2 5.7 0.1 62.2 12.8 70.4 2.3 4.4 10.1 1.6 1.8 3.4 4.9 24.5 2.0 4.8 0.2 0.5 10.3 10.6 0.0 2.8 5.9 2.9 7.0 9.2 104.6 5.3 9.1 4.4 0.7 9.3 2.3 9.6 1.7 1.1 7.3 0.3 0.0 1.6 5.9 4.5 3.6 10.3 2.4 1.8 3.2 1.2 16.0 10.5 15.9 23.5 2.3 8.0 16.4 27.1 14.2 11.4 1.9 9.3 8.5 0.9 0.2 12.0 3.3 3.5 0.1 0.5 10.3 17.3 2.7 4.2 2.0 57.9 1.5 0.1 1.5 11.0 1.4 0.7 1.4 11.3 0.9 0.7 3.1 0.4 0.2 0.0 0.8 1.1 3.3 9.9 0.0 11.3 4.4 4.2 7.0 2.0 1.2 0.8 3.8 5.7 22.5 32.1 110.0 619.3 32.3 10.6 30.1 6.6 35.3 20.2 5.1 2.7 35.7 8.6 30.2 42.3 73.0 11.3 118.6 28.1 11.7 0.6 21.4 19.0 8.6 16.9 33.4 2.1 2969.7 1.8 25.7 27.5 40.2 21.9 22.2 0.3 17.2 0.8 5.2 1.7 1116.9 18.2 6.1 4.8 11.1 36.6 1.5 29.5 10.6 407.5 6.0 12.0 29.9 848.0 443.3 8.2 11.9 4.9 44.4 43.3 8.9 27.5 19.4 52.8 0.0 64.0 6.3 1.1 7.7 40.6 8.8 3.1 94.3 1.1 11.7 26.5 PDE9A ENSG00000160191 "Phosphodiesterase 9A" O76083 21 42653621-42775509 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 74.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 90.8;Paneth cells: 105.3;Proximal enterocytes: 233.5" "Cancer enriched" "Detected in all" 5 "prostate cancer: 31.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 3.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 29.7;EFO-21: 30.0;MCF7: 23.2;NB-4: 34.7;NTERA-2: 41.2;SCLC-21H: 22.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011380, HPA011978" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 45: Enterocytes - Digestion" Cytosol "Nucleoplasm, Plasma membrane" "HPA011380: AB_1855132, HPA011978: " "unprognostic (5.75e-2)" "unprognostic (9.92e-3)" "unprognostic (3.50e-1)" "unprognostic (1.08e-1)" "unprognostic (1.44e-1)" "unprognostic (1.40e-1)" "unprognostic (5.06e-2)" "unprognostic (3.99e-2)" "unprognostic (6.02e-2)" "unprognostic (1.60e-1)" "unprognostic (1.25e-2)" "unprognostic (5.01e-2)" "unprognostic (1.90e-2)" "unprognostic (4.01e-3)" "unprognostic (1.97e-1)" "unprognostic (6.55e-2)" "unprognostic (1.79e-1)" 9.4 11.1 12.3 3.9 15.1 0.5 10.8 14.0 12.9 7.2 8.6 74.7 2.9 5.1 19.4 3.7 10.6 6.8 4.3 10.6 12.6 29.8 4.2 4.9 4.8 12.4 14.4 3.5 4.1 6.5 9.9 10.3 12.7 38.5 16.4 10.7 12.7 15.8 2.4 7.0 47.3 8.8 11.0 18.3 13.4 1.9 15.0 7.8 6.5 4.8 3.1 18.9 6.2 12.0 0.0 2.8 29.7 3.7 0.0 0.8 0.5 0.0 0.0 0.0 0.0 3.2 18.2 0.0 30.0 0.0 2.2 0.0 2.7 9.8 0.0 0.0 10.4 0.0 0.0 6.4 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.5 0.0 0.0 23.2 1.5 34.7 41.2 14.6 0.0 0.0 0.0 1.2 20.4 7.6 22.5 13.5 5.2 0.0 0.5 7.0 0.2 19.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.9 0.2 0.1 0.2 3.1 0.6 0.4 0.9 0.0 0.4 1.0 0.3 12.3 15.1 14.0 12.9 10.6 12.6 12.4 14.4 12.7 11.0 15.0 12.0 18.6 3.2 5.0 43.4 1.6 1.0 10.9 4.2 6.2 26.4 13.4 12.6 1.6 5.7 2.4 18.4 0.0 0.0 1.0 90.8 29.4 7.3 0.6 18.1 8.5 11.9 13.1 3.2 5.6 2.4 0.1 5.9 1.5 26.8 1.3 6.1 5.7 0.9 7.5 35.3 10.8 25.8 8.2 1.3 0.8 2.2 11.8 1.6 28.4 31.9 1.1 11.0 0.0 29.1 16.6 5.3 105.3 6.0 0.2 28.1 233.5 8.9 1.3 2.8 13.1 0.5 6.4 0.4 2.3 0.5 0.6 0.4 3.8 16.9 24.4 15.0 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDGFRA "CD140a, GAS9, PDGFR2" ENSG00000134853 "Platelet derived growth factor receptor alpha" P16234 4 54229280-54298245 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Chemotaxis, Host-virus interaction" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 190.2" "Group enriched" "Detected in many" 8 "Endometrial stromal cells: 423.9;Fibroblasts: 256.4;Leydig cells: 449.8;Oligodendrocyte precursor cells: 499.6;Peritubular cells: 408.9" "Cancer enhanced" "Detected in all" "glioma: 30.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 468.1;ASC TERT1: 216.1;BJ hTERT+: 279.4;fHDF/TERT166: 195.9;HHSteC: 156.3;HSkMC: 392.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004947, CAB018143" Supported Approved "Nucleoplasm,Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA 300000 "Cluster 34: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Nucleoplasm, Plasma membrane, Cell Junctions" "CAB018143: AB_2162351, HPA004947: AB_2732399" "unprognostic (1.67e-1)" "unprognostic (9.35e-2)" "unprognostic (4.59e-3)" "unprognostic (1.60e-1)" "unprognostic (8.92e-2)" "prognostic favorable (9.33e-4)" "unprognostic (1.24e-1)" "unprognostic (2.00e-2)" "unprognostic (1.46e-1)" "unprognostic (2.18e-2)" "unprognostic (2.18e-1)" "unprognostic (7.01e-2)" "prognostic unfavorable (9.79e-6)" "unprognostic (9.58e-3)" "unprognostic (9.87e-2)" "unprognostic (2.16e-2)" "unprognostic (1.72e-3)" 46.0 28.9 13.9 40.4 13.7 1.6 40.1 8.1 12.8 50.8 18.1 37.7 22.4 44.3 21.8 22.5 50.9 38.5 32.1 11.9 11.0 26.5 16.0 37.9 8.5 16.7 11.9 190.2 13.4 3.0 3.7 62.7 15.1 15.0 35.2 5.3 16.6 18.9 9.6 14.8 31.3 48.1 12.1 46.2 29.4 13.6 8.9 7.6 16.5 41.9 7.2 63.9 38.0 20.0 0.1 0.0 1.0 0.8 468.1 216.1 0.5 25.4 279.4 0.1 0.7 67.6 0.5 0.5 0.5 195.9 0.8 0.6 19.6 0.2 0.1 2.6 1.0 0.7 0.7 1.2 156.3 0.3 0.4 392.0 0.0 31.4 0.0 5.4 0.0 0.7 0.6 0.9 1.1 0.1 0.4 1.2 3.5 0.3 1.1 0.5 0.1 0.1 0.0 0.4 0.6 37.9 0.0 0.5 0.2 2.0 0.7 0.1 0.8 84.9 3.2 93.9 0.2 0.4 0.1 0.8 2.6 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 13.9 13.7 8.1 12.8 11.9 11.0 16.7 11.9 15.1 12.1 8.9 20.0 11.1 0.0 0.5 0.3 0.6 17.1 0.6 2.4 1.2 5.5 4.3 3.2 4.8 0.0 0.8 0.0 0.0 1.4 0.9 0.1 1.9 4.2 2.2 11.7 423.9 5.7 0.0 0.0 1.1 6.7 2.0 256.4 5.1 9.0 0.0 2.6 26.0 1.0 3.1 0.0 19.5 0.2 10.2 0.6 27.3 17.2 449.8 5.4 23.2 39.4 4.7 17.5 0.0 499.6 0.4 20.0 0.0 408.9 0.2 0.9 0.0 0.1 0.5 0.6 0.0 25.7 13.9 1.0 3.4 8.1 15.8 1.4 2.5 49.6 0.0 1.0 PDHX "DLDBP, E3BP, OPDX, PDX1, proX" ENSG00000110435 "Pyruvate dehydrogenase complex component X" O00330 11 34915829-35020591 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.6;tongue: 125.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 115.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038484, HPA038485" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Plasma membrane" Mitochondria "HPA038484: AB_10669645, HPA038485: AB_10669540" "unprognostic (1.60e-1)" "unprognostic (1.91e-1)" "unprognostic (1.42e-2)" "unprognostic (1.06e-1)" "unprognostic (2.03e-1)" "unprognostic (8.34e-3)" "unprognostic (3.56e-3)" "unprognostic (1.94e-1)" "unprognostic (2.14e-1)" "unprognostic (5.41e-2)" "unprognostic (2.60e-2)" "unprognostic (2.08e-1)" "prognostic favorable (1.83e-5)" "unprognostic (2.24e-1)" "unprognostic (8.28e-2)" "unprognostic (9.53e-2)" "unprognostic (2.82e-1)" 23.5 21.6 16.5 12.2 19.9 7.4 16.6 21.6 21.9 13.3 9.4 22.8 20.1 14.2 13.3 17.2 10.0 12.3 77.8 21.1 14.5 21.5 31.0 12.7 11.9 16.6 17.2 11.7 21.5 21.0 15.4 24.4 16.5 18.9 20.6 27.1 20.4 16.0 138.6 14.6 15.0 17.8 13.4 11.1 23.1 27.8 19.7 13.2 14.3 125.2 14.8 15.0 11.7 21.1 20.4 54.3 29.9 11.9 20.7 25.5 28.5 38.9 30.1 40.3 38.9 69.3 18.8 27.2 24.7 31.4 49.1 39.4 58.9 31.9 41.1 25.8 47.2 26.9 54.6 82.3 45.0 50.7 30.7 25.6 37.9 23.2 31.5 23.8 31.1 23.9 57.9 25.4 33.1 35.7 32.2 29.9 25.2 54.2 30.5 27.0 53.5 23.8 62.1 54.7 32.0 23.3 33.8 48.1 52.2 29.3 54.8 29.9 21.0 30.4 35.5 32.3 42.7 24.4 53.3 35.7 23.9 24.2 32.5 14.0 19.4 17.5 15.4 21.4 14.3 18.8 14.4 12.7 27.5 16.0 17.2 12.6 3.9 22.1 34.6 7.4 22.1 14.7 16.5 19.9 21.6 21.9 21.1 14.5 16.6 17.2 16.5 13.4 19.7 21.1 9.0 35.3 24.6 34.3 14.5 26.0 21.4 26.7 15.4 25.8 15.1 11.4 115.3 20.0 26.0 5.5 29.2 62.9 9.0 14.4 64.6 21.4 52.6 15.1 12.2 13.0 9.0 13.5 85.4 14.3 34.9 20.6 16.3 16.6 5.7 16.5 11.7 23.6 26.4 20.2 80.3 17.2 42.7 18.6 13.6 54.0 10.8 14.7 21.4 24.4 23.2 21.0 9.2 40.2 53.4 16.7 15.9 13.5 14.1 22.4 15.0 30.7 19.8 26.7 0.0 14.5 18.8 57.2 36.1 17.9 25.4 83.0 13.4 27.5 20.0 19.7 PDLIM1 "CLIM1, CLP-36, CLP36, hCLIM1" ENSG00000107438 "PDZ and LIM domain 1" O00151 10 95237572-95291012 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 675.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 805.9;Basal respiratory cells: 763.8;Paneth cells: 769.2;Proximal enterocytes: 1059.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "eosinophil: 189.7;memory B-cell: 223.8;naive B-cell: 213.0" "Group enriched" "Detected in all" 7 "B-cells: 223.8;granulocytes: 189.7" "Cell line enhanced" "Detected in many" "HaCaT: 766.3;Hep G2: 635.3;HHSteC: 731.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017010, CAB072838, CAB072840" Approved Supported "Plasma membrane,Cell Junctions,Actin filaments" NA NA 93000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane, Cell Junctions" "CAB072838: , CAB072840: , HPA017010: AB_1855147" "unprognostic (1.61e-1)" "unprognostic (2.87e-2)" "unprognostic (2.58e-2)" "prognostic favorable (1.14e-5)" "unprognostic (3.18e-2)" "unprognostic (7.54e-2)" "unprognostic (2.07e-1)" "unprognostic (8.99e-2)" "unprognostic (2.26e-1)" "unprognostic (2.82e-3)" "unprognostic (5.77e-2)" "unprognostic (6.56e-2)" "unprognostic (1.27e-2)" "unprognostic (2.00e-1)" "unprognostic (1.97e-1)" "unprognostic (4.21e-3)" "unprognostic (1.11e-1)" 301.7 32.4 10.7 91.5 10.8 25.0 236.0 10.2 18.5 133.1 30.2 220.0 179.4 115.0 91.8 182.3 155.3 114.9 393.2 11.7 10.9 82.8 160.3 337.2 104.5 20.4 12.7 35.6 98.3 65.9 29.5 141.1 14.1 116.9 218.5 36.9 166.1 114.7 675.1 136.8 249.0 146.0 14.0 148.3 148.3 13.7 13.8 105.9 194.7 290.0 123.7 276.3 165.3 11.2 274.4 181.8 12.4 0.4 64.1 43.3 277.1 82.6 266.4 218.8 356.5 387.0 429.8 0.3 21.9 233.8 110.4 766.3 91.5 498.1 220.6 0.2 132.0 277.9 50.1 635.3 731.0 0.1 13.2 125.5 257.0 111.9 400.6 233.2 396.8 24.2 60.0 70.3 52.7 51.4 0.8 4.9 24.6 137.7 137.2 234.1 10.0 98.4 114.4 268.9 48.3 18.9 91.2 84.6 0.9 293.8 68.2 125.7 345.1 84.5 19.7 0.7 0.7 31.2 0.1 91.6 92.5 0.2 41.0 0.4 2.4 189.7 11.9 0.8 0.1 223.8 2.3 14.1 31.0 213.0 0.5 8.1 7.5 8.9 1.5 3.2 2.2 44.5 10.7 10.8 10.2 18.5 11.7 10.9 20.4 12.7 14.1 14.0 13.8 11.2 435.0 76.9 123.5 0.0 145.6 366.3 805.9 763.8 244.7 10.1 100.6 131.4 266.2 223.1 250.2 51.5 29.2 538.2 20.5 657.0 15.6 420.1 8.4 218.6 319.3 359.3 101.3 41.6 0.9 172.5 116.7 149.2 100.9 113.0 12.6 47.2 459.7 100.4 50.0 1.7 0.4 488.9 152.5 19.4 105.2 8.0 5.0 88.8 40.9 2.8 8.8 11.6 32.0 0.0 0.0 227.0 769.2 0.7 103.5 256.5 1059.7 109.0 316.4 59.5 315.5 21.0 213.1 4.3 35.7 170.4 197.9 117.0 25.8 1.9 419.2 554.3 PDLIM5 "Enh, LIM" ENSG00000163110 "PDZ and LIM domain 5" Q96HC4 4 94451857-94668227 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "heart muscle: 629.5;skeletal muscle: 1163.5;tongue: 576.0" "Cell type enriched" "Detected in all" 4 "Cardiomyocytes: 1844.2" "Cancer enriched" "Detected in all" 8 "prostate cancer: 132.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 219.7" "Lineage enriched" "Detected in all" 5 "granulocytes: 219.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013511, HPA016740, HPA020026" Enhanced Approved "Nucleoplasm,Plasma membrane,Focal adhesion sites" NA NA 1200000 "Cluster 38: Basophils - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Focal adhesion sites" "CAB013511: AB_2533388, HPA016740: AB_1855153, HPA020026: AB_1855154" "unprognostic (6.20e-2)" "unprognostic (1.94e-1)" "unprognostic (2.81e-2)" "unprognostic (1.08e-2)" "unprognostic (6.61e-2)" "unprognostic (2.24e-1)" "unprognostic (1.33e-1)" "unprognostic (2.46e-2)" "unprognostic (7.60e-2)" "unprognostic (2.65e-1)" "unprognostic (1.18e-2)" "unprognostic (1.47e-1)" "unprognostic (1.24e-1)" "unprognostic (2.11e-2)" "unprognostic (3.15e-2)" "unprognostic (1.91e-1)" "unprognostic (1.04e-1)" 41.7 26.0 20.5 25.6 25.2 59.7 39.5 22.4 22.4 27.4 84.9 34.1 33.3 94.8 11.3 72.3 40.5 47.5 629.5 21.4 27.7 34.9 82.7 22.0 16.2 30.9 30.1 27.2 30.2 12.2 17.5 67.7 25.0 88.5 30.8 18.2 40.2 68.9 1163.5 21.5 34.4 105.9 22.7 24.1 31.0 12.7 26.3 10.9 25.5 576.0 21.1 45.8 27.6 21.0 31.4 87.2 33.6 13.0 71.7 51.3 13.0 71.6 59.9 40.1 32.6 80.8 66.3 12.0 72.0 72.3 21.0 31.8 46.5 68.2 65.9 24.1 19.3 43.7 53.8 32.2 103.7 14.6 38.3 66.4 58.4 96.1 74.0 177.9 93.5 13.2 19.2 12.5 86.2 29.8 15.0 4.8 11.4 66.7 36.6 7.2 24.7 11.1 45.0 94.6 16.5 21.8 38.9 88.7 20.3 26.7 10.3 5.2 113.7 103.7 17.3 46.1 44.1 9.5 13.0 12.7 56.5 10.3 24.9 219.7 23.4 21.0 12.1 40.6 9.7 10.5 12.0 12.8 19.5 7.6 7.9 10.4 22.6 9.2 44.6 6.6 11.8 15.2 20.5 25.2 22.4 22.4 21.4 27.7 30.9 30.1 25.0 22.7 26.3 21.0 107.4 44.8 23.6 184.1 22.1 194.4 380.3 92.1 63.7 4.7 90.2 67.4 1844.2 62.9 82.9 49.7 31.3 13.7 18.5 180.0 13.7 95.0 19.2 68.7 11.8 117.2 109.4 27.6 4.9 95.1 96.5 97.8 84.6 108.7 52.0 29.1 137.8 207.0 38.8 1.7 20.7 107.4 36.7 60.6 75.3 9.1 41.3 59.8 62.2 104.0 41.6 86.2 12.3 181.5 43.1 139.2 166.8 66.5 23.2 300.7 117.5 73.6 70.0 35.8 78.9 96.7 134.7 23.8 34.4 107.3 157.0 23.8 31.1 6.8 74.0 217.5 PDPN "aggrus, Gp38, GP40, PA2.26, T1A-2" ENSG00000162493 Podoplanin Q86YL7 1 13583465-13617957 "Predicted membrane proteins" "Cell shape" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 135.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 105.8;Basal respiratory cells: 98.5;Fibroblasts: 123.1;monocytes: 116.3;Muller glia cells: 97.7;Peritubular cells: 62.8" "Group enriched" "Detected in many" 4 "glioma: 83.2;head and neck cancer: 40.2;testis cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 149.5;EFO-21: 356.4;HAP1: 253.3;HHSteC: 216.0;NTERA-2: 116.0;SuSa: 119.0;TIME: 242.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007534, HPA007949, CAB008376" Enhanced Supported "Plasma membrane,Cell Junctions,Mitochondria" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 38: EFO-21 - Unknown function" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "Cell Junctions, Mitochondria" "CAB008376: AB_592530, HPA007534: AB_1857718, HPA007949: " "unprognostic (1.75e-1)" "unprognostic (3.19e-2)" "unprognostic (6.03e-2)" "unprognostic (3.61e-2)" "unprognostic (2.73e-2)" "unprognostic (1.05e-2)" "unprognostic (3.85e-2)" "unprognostic (5.23e-2)" "unprognostic (9.21e-2)" "unprognostic (1.29e-1)" "unprognostic (1.13e-2)" "unprognostic (1.92e-2)" "unprognostic (5.62e-3)" "unprognostic (9.20e-3)" "unprognostic (1.21e-1)" "unprognostic (3.29e-2)" "unprognostic (2.78e-2)" 61.5 3.3 8.9 55.9 9.3 0.0 20.9 13.7 8.1 43.1 23.5 16.6 3.8 25.9 11.3 15.8 33.4 42.1 20.3 8.0 14.6 3.4 0.6 32.4 9.8 24.9 15.6 29.4 6.4 1.1 3.3 135.6 19.1 14.0 10.6 22.7 9.1 14.1 30.0 20.0 15.9 34.5 16.4 0.3 24.7 4.5 22.5 10.3 6.2 11.3 18.5 96.1 25.2 21.2 0.1 0.0 149.5 0.1 0.5 0.0 0.1 2.4 0.1 0.0 0.0 0.0 0.1 0.2 356.4 9.0 0.1 0.7 253.3 44.7 0.0 1.0 46.1 0.1 0.0 0.0 216.0 0.0 0.2 29.5 82.9 18.6 21.8 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 116.0 0.0 0.6 0.3 0.2 0.1 0.0 4.0 0.1 0.1 0.2 0.0 0.3 119.0 0.1 0.6 242.2 41.8 34.6 0.6 0.1 0.1 0.3 1.0 88.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.9 9.3 13.7 8.1 8.0 14.6 24.9 15.6 19.1 16.4 22.5 21.2 2.4 105.8 11.2 3.9 0.2 14.5 30.4 98.5 14.8 1.4 0.5 19.9 8.4 2.8 18.8 0.0 4.2 2.0 0.1 0.0 0.0 0.5 0.7 1.6 37.6 22.4 0.0 0.0 2.6 0.0 2.1 123.1 0.0 2.8 1.3 3.4 6.4 0.0 6.5 0.0 3.5 0.0 8.2 0.0 14.0 1.8 20.2 5.3 7.2 5.6 116.3 97.7 0.0 19.6 0.2 0.4 0.0 62.8 0.0 15.8 0.0 0.0 5.4 3.4 0.0 17.0 8.4 1.0 8.2 3.9 7.0 2.9 1.3 0.9 0.0 3.4 PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 232.9;Excitatory neurons: 313.2;Oligodendrocyte precursor cells: 745.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.1;EFO-21: 4.5;SiHa: 11.6;SK-BR-3: 10.6;T-47d: 5.5" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" 16.5 0.9 4.5 0.7 24.8 0.1 5.0 0.7 15.7 2.2 10.6 1.4 0.5 2.5 1.9 5.3 2.2 0.9 18.8 4.7 0.3 8.2 0.1 9.0 0.3 4.5 4.3 14.4 1.2 0.6 1.8 10.9 1.0 1.5 0.7 14.8 1.6 1.9 2.5 10.1 0.6 2.4 0.3 0.2 1.7 5.6 4.1 2.6 1.0 4.8 1.7 0.6 2.1 0.0 0.1 0.0 3.1 0.1 0.0 0.0 8.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 4.5 0.0 1.2 4.3 1.7 0.9 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 2.2 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 3.5 0.0 0.1 0.7 11.6 10.6 0.0 2.6 5.5 0.0 0.0 0.0 2.2 0.0 0.5 0.0 0.0 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 24.8 0.7 15.7 4.7 0.3 4.5 4.3 1.0 0.3 4.1 0.0 26.2 44.8 38.6 39.2 0.2 16.8 4.4 14.0 13.6 7.0 10.6 6.9 53.9 0.0 9.3 5.5 98.0 25.5 1.9 0.1 0.0 0.2 232.9 9.7 16.9 14.7 0.0 1.3 313.2 0.2 3.4 8.6 7.7 33.2 1.3 18.7 5.7 0.2 2.2 15.2 113.2 0.0 4.1 0.3 3.1 55.2 7.5 1.0 7.2 87.1 0.2 6.4 0.0 745.0 104.7 3.5 0.0 10.5 0.1 3.5 0.0 8.2 2.8 62.1 46.0 7.3 13.4 12.3 3.8 15.1 18.5 21.1 1.3 46.8 0.0 1.8 PDZD8 "bA129M16.2, FLJ34427, PDZK8" ENSG00000165650 "PDZ domain containing 8" Q8NEN9 10 117277274-117375440 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.0" "Cell type enhanced" "Detected in all" "Early spermatids: 208.7;Late spermatids: 477.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 124.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015716, HPA051610" Uncertain Approved "Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA015716: AB_1855162, HPA051610: AB_2681549" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (9.65e-3)" "unprognostic (2.75e-2)" "unprognostic (6.29e-2)" "unprognostic (3.36e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.53e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.90e-2)" "unprognostic (5.37e-3)" "unprognostic (7.60e-3)" "unprognostic (1.44e-2)" "unprognostic (3.18e-2)" "unprognostic (2.01e-2)" 7.1 7.0 8.9 4.7 12.1 73.0 4.7 15.7 8.6 7.9 17.9 9.3 14.0 9.1 14.1 10.8 6.8 9.7 5.1 8.1 11.8 13.1 15.8 6.0 3.2 11.9 13.8 8.9 14.1 28.3 4.2 5.4 12.2 6.4 11.2 14.1 12.9 10.6 4.9 5.5 10.6 6.9 11.3 3.7 10.4 13.2 12.5 5.8 6.8 5.8 3.6 6.6 5.8 13.2 12.6 21.1 7.6 14.7 12.8 11.4 4.3 11.9 10.2 5.2 4.2 10.7 16.4 14.7 10.5 18.1 6.0 18.4 13.4 12.6 10.3 9.4 11.8 124.3 8.6 10.6 9.4 52.4 11.2 11.2 14.7 9.5 27.9 19.3 9.3 12.1 11.5 15.0 13.0 5.1 10.2 6.7 6.0 6.6 18.8 8.2 29.2 6.4 15.5 9.0 6.0 9.6 12.6 5.4 9.7 6.9 3.7 7.6 15.1 8.6 9.4 15.8 20.5 8.0 7.2 10.5 10.8 23.6 7.7 1.4 0.5 2.6 0.9 0.5 0.9 0.3 0.7 0.7 0.7 0.4 0.5 0.7 2.3 1.2 0.9 0.5 0.3 0.2 8.9 12.1 15.7 8.6 8.1 11.8 11.9 13.8 12.2 11.3 12.5 13.2 22.1 12.8 30.7 32.3 13.7 29.7 24.4 10.3 24.5 31.9 16.4 17.0 19.8 40.0 21.0 18.4 22.9 9.8 36.1 26.9 9.8 31.9 208.7 78.3 46.7 24.0 33.7 82.0 49.2 81.9 7.2 27.3 48.4 111.2 44.2 14.6 18.9 58.6 7.5 32.0 61.0 38.8 10.2 16.0 31.8 477.6 23.6 25.2 23.2 30.0 15.5 29.0 23.7 51.8 56.4 57.6 23.1 28.6 28.1 41.1 27.0 26.5 28.5 45.0 26.3 46.3 24.5 25.8 29.1 36.3 32.4 6.7 28.4 90.8 50.2 44.6 PEAR1 "FLJ00193, JEDI, MEGF12" ENSG00000187800 "Platelet endothelial aggregation receptor 1" Q5VY43 1 156893698-156916434 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 44.6;Endothelial cells: 30.6;Hepatic stellate cells: 40.0;Leydig cells: 44.4;Peritubular cells: 35.7;Sertoli cells: 26.3;Smooth muscle cells: 34.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 19.5;HBEC3-KT: 29.9;HHSteC: 21.6;HUVEC TERT2: 52.2;TIME: 85.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035217 Approved Approved "Nucleoplasm,Cell Junctions,Centrosome" NA NA 62000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Cell Junctions" Centrosome "HPA035217: AB_10669902" "unprognostic (1.02e-1)" "unprognostic (1.84e-5)" "unprognostic (4.77e-2)" "unprognostic (1.67e-1)" "unprognostic (1.34e-1)" "unprognostic (2.48e-1)" "unprognostic (5.62e-2)" "unprognostic (5.93e-2)" "unprognostic (1.04e-2)" "unprognostic (3.99e-1)" "unprognostic (2.17e-1)" "unprognostic (5.04e-1)" "prognostic unfavorable (4.31e-4)" "unprognostic (1.20e-2)" "unprognostic (3.37e-3)" "unprognostic (8.51e-2)" "unprognostic (2.64e-2)" 19.0 5.0 2.5 2.3 3.0 2.3 12.9 1.2 4.1 12.3 2.0 4.5 1.6 10.0 1.1 2.6 9.1 7.4 8.7 1.2 1.7 4.8 2.1 11.8 3.8 2.0 2.3 9.1 2.3 1.7 3.4 11.7 2.3 4.7 0.9 0.4 2.9 3.7 5.7 4.2 4.1 4.6 1.1 7.0 3.7 3.0 2.9 1.4 9.7 7.6 1.1 6.0 7.3 1.4 0.5 2.9 0.8 0.0 0.0 3.7 0.1 11.7 19.5 4.8 2.8 0.3 0.5 0.0 0.6 8.7 0.4 0.2 0.0 29.9 1.3 0.2 0.0 14.8 0.7 0.8 21.6 0.1 0.0 11.3 0.1 6.5 1.5 1.0 52.2 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.7 0.0 11.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.1 0.0 6.9 0.0 0.0 85.2 0.1 6.4 2.6 0.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 2.5 3.0 1.2 4.1 1.2 1.7 2.0 2.3 2.3 1.1 2.9 1.4 44.6 0.0 3.2 0.0 0.4 0.9 0.1 0.7 1.2 2.4 0.6 1.3 7.5 1.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.2 0.2 2.5 30.6 1.8 5.7 0.0 0.4 0.1 10.1 1.5 0.4 1.3 0.1 40.0 0.4 0.5 0.0 0.0 2.3 0.0 1.6 1.5 3.5 44.4 3.0 5.4 12.2 0.4 0.2 0.0 0.0 0.0 1.2 0.0 35.7 0.0 0.2 0.0 0.1 0.2 0.2 26.3 1.7 34.2 1.5 1.5 0.2 1.1 0.3 0.3 1.1 0.3 0.2 PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2083.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 3705.6;Hepatocytes: 2242.4;Proximal enterocytes: 2177.7;Proximal tubular cells: 4542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904" Enhanced Approved "Plasma membrane,Cytosol" NA NA 51000000 "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB009906: AB_2163173, CAB013493: AB_2533305, HPA008819: AB_1855173, HPA063904: AB_2732708" "unprognostic (4.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.28e-2)" "unprognostic (3.39e-3)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (7.35e-3)" "unprognostic (5.67e-2)" "unprognostic (3.55e-2)" "prognostic favorable (1.52e-4)" "unprognostic (1.63e-1)" "prognostic favorable (2.15e-13)" "unprognostic (2.17e-1)" "unprognostic (7.72e-2)" "unprognostic (7.96e-2)" "unprognostic (8.80e-2)" 217.9 1754.1 941.2 84.0 966.0 121.8 235.5 987.9 1049.0 258.0 958.4 208.9 601.4 186.6 383.7 219.5 218.4 154.8 463.8 932.6 951.5 1046.1 2083.1 176.4 122.7 959.0 965.9 335.9 357.5 1162.7 292.3 128.8 982.6 261.6 191.2 336.1 344.5 233.2 580.3 190.3 510.6 167.6 1006.6 121.2 201.7 152.2 1025.0 138.1 739.7 546.8 160.2 200.8 179.0 1081.7 289.2 241.6 340.0 348.8 493.5 250.2 500.0 214.5 262.3 347.7 177.1 151.6 96.4 439.6 221.3 336.2 139.9 194.4 495.0 202.8 257.7 115.1 454.2 220.0 274.7 1021.7 289.2 403.6 94.5 240.8 334.7 203.9 140.0 396.1 162.7 240.9 375.8 169.2 356.4 346.3 226.8 813.7 319.7 243.1 273.9 446.1 235.6 829.7 428.7 277.2 397.5 306.9 439.9 306.2 446.0 200.4 443.6 293.0 168.9 253.7 147.0 254.0 237.3 161.6 315.1 234.1 301.1 303.2 280.9 5.0 67.5 20.0 155.2 76.4 247.0 271.7 258.9 193.1 205.1 210.0 244.6 201.2 8.0 138.1 68.6 231.6 259.7 258.4 941.2 966.0 987.9 1049.0 932.6 951.5 959.0 965.9 982.6 1006.6 1025.0 1081.7 193.7 403.8 433.3 101.5 230.9 318.1 449.3 367.6 288.5 539.4 538.4 590.7 697.3 713.4 243.2 783.5 95.9 999.6 144.6 207.1 3705.6 507.9 44.3 499.3 319.0 186.5 320.6 218.1 93.7 244.6 862.3 347.9 169.2 369.8 371.8 419.7 213.8 2242.4 591.6 721.8 99.6 378.8 335.7 201.4 239.0 84.4 543.1 195.3 743.5 53.4 296.8 1792.2 101.0 39.2 199.8 184.2 313.3 731.6 279.3 517.4 2177.7 4542.6 291.6 411.6 368.1 337.5 347.8 330.6 145.7 367.7 325.2 615.5 216.7 921.6 631.3 399.5 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PFDN1 PFD1 ENSG00000113068 "Prefoldin subunit 1" O60925 5 140245035-140303113 "Predicted intracellular proteins, Predicted membrane proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006499 Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" Nucleoli "HPA006499: AB_1079596" "unprognostic (2.73e-1)" "unprognostic (1.48e-1)" "unprognostic (1.37e-1)" "unprognostic (3.00e-2)" "unprognostic (6.11e-2)" "unprognostic (5.66e-3)" "prognostic unfavorable (8.81e-5)" "unprognostic (2.12e-2)" "unprognostic (2.19e-1)" "unprognostic (1.89e-1)" "unprognostic (1.50e-1)" "unprognostic (2.33e-1)" "unprognostic (4.10e-1)" "unprognostic (8.60e-3)" "unprognostic (2.53e-1)" "unprognostic (3.53e-2)" "unprognostic (3.00e-1)" 74.1 50.9 73.9 37.7 75.6 60.2 50.0 82.2 88.4 41.4 70.8 59.2 40.2 50.8 54.3 52.3 41.9 35.7 93.3 77.2 79.7 61.6 38.5 46.9 46.1 82.9 77.2 37.2 34.7 52.8 39.4 50.8 80.5 44.8 42.9 35.1 45.4 43.7 149.0 46.2 39.8 61.4 79.1 36.6 40.7 29.9 79.3 51.5 42.4 86.4 51.6 45.9 40.9 81.2 172.4 79.6 137.7 80.9 89.7 91.8 133.8 229.6 114.9 174.6 192.6 172.1 107.9 114.9 224.1 124.3 180.0 62.6 102.0 228.7 204.2 122.6 102.9 102.4 76.5 113.0 105.1 213.5 76.4 98.2 119.8 148.5 156.3 112.6 196.0 132.8 93.7 73.1 149.8 78.5 146.0 147.6 92.0 70.3 119.2 101.3 195.9 86.3 197.1 77.9 78.2 81.8 172.1 148.6 136.8 128.5 102.1 122.3 249.1 121.8 119.6 71.9 208.0 70.3 198.6 299.2 122.5 138.5 144.1 149.5 84.7 130.3 86.2 131.1 91.8 106.0 98.6 100.4 100.5 97.9 97.3 88.4 14.0 114.7 130.3 93.0 129.3 115.5 73.9 75.6 82.2 88.4 77.2 79.7 82.9 77.2 80.5 79.1 79.3 81.2 87.9 67.3 33.0 16.3 57.4 38.0 65.9 96.2 30.7 42.5 50.1 57.3 81.3 52.9 62.1 66.2 45.9 116.1 53.1 56.6 123.3 121.9 3.9 58.0 56.6 73.8 46.6 62.9 31.2 101.7 86.6 55.4 35.2 70.9 54.4 53.6 72.1 56.9 85.4 25.2 29.3 43.6 48.8 61.1 37.7 12.9 52.2 63.4 74.7 37.5 90.4 84.9 71.1 24.1 39.3 128.9 55.1 52.3 35.5 45.4 80.9 147.3 45.3 42.9 65.7 39.6 63.7 23.7 61.8 40.8 34.9 85.6 45.2 42.9 47.3 63.6 PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "OE19: 800.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" 10.5 11.9 17.0 5.6 17.2 5.0 12.9 14.0 19.6 14.6 16.2 18.6 14.9 11.3 18.3 25.8 15.9 13.4 14.8 17.5 16.7 20.6 35.6 12.1 7.4 14.9 15.4 13.5 27.1 22.7 14.9 11.8 14.6 18.5 13.7 7.1 25.1 11.7 8.3 21.0 17.1 6.1 14.7 12.3 16.6 9.1 16.5 4.8 27.1 4.5 7.5 12.2 13.7 15.5 3.7 9.6 7.7 7.0 7.9 8.1 7.9 4.3 10.1 6.7 6.1 5.4 23.8 4.2 19.7 8.3 2.2 12.6 2.4 2.9 3.1 8.6 7.7 5.2 6.0 9.3 10.6 12.9 12.8 14.9 15.0 3.1 6.8 7.6 2.2 1.9 4.9 9.6 6.1 8.7 2.9 11.7 7.6 800.4 2.1 3.2 4.7 12.1 10.7 12.0 7.1 4.7 11.9 134.0 6.9 0.8 11.4 12.4 3.4 7.2 7.6 3.5 3.3 8.5 2.0 1.4 8.1 4.9 8.1 2.6 7.2 4.6 15.2 11.6 8.3 8.1 10.6 12.5 5.7 7.7 10.1 10.1 2.0 10.4 4.3 3.9 5.4 7.3 17.0 17.2 14.0 19.6 17.5 16.7 14.9 15.4 14.6 14.7 16.5 15.5 6.5 3.2 14.9 7.8 3.7 3.8 3.3 5.6 3.4 12.6 9.1 7.0 7.7 14.3 10.1 14.7 8.4 8.1 5.3 20.3 1.9 7.6 0.1 3.5 4.5 5.0 8.4 3.0 9.0 11.1 6.5 5.1 9.2 5.7 8.9 6.8 4.6 9.0 4.4 13.5 6.3 15.3 8.2 5.1 2.8 0.1 3.1 3.7 1.8 2.8 1.9 7.5 4.1 9.0 6.1 6.3 13.9 1.5 2.8 3.7 22.9 3.4 4.9 22.1 0.0 5.0 3.3 0.7 2.4 8.1 2.8 10.4 4.9 5.8 13.3 3.1 PGLYRP2 "PGLYRPL, PGRP-L, PGRPL, tagL, tagL-alpha, tagl-beta, TAGL-like" ENSG00000161031 "Peptidoglycan recognition protein 2" Q96PD5 19 15468645-15498956 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 45 "liver: 258.8" "Cell type enriched" "Detected in some" 11 "Hepatocytes: 168.7" "Cancer enriched" "Detected in some" 16 "liver cancer: 42.9" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "granulocytes: 3.4;monocytes: 5.1;T-cells: 2.3" "Group enriched" "Detected in some" 5 "MCF7: 8.1;T-47d: 8.4" "Not detected" "Not detected" "Not detected" "Not detected" "CAB033468, HPA046311, HPA075237" Supported Approved "Cell Junctions" "Secreted to blood" NA NA 87000000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 62: Liver - Hemostasis" "Cluster 6: T47d - Mammary gland" "Cluster 2: Hepatocytes - Metabolism" "Cell Junctions" "CAB033468: AB_1127187, HPA046311: AB_2679621, HPA075237: AB_2686739" "unprognostic (7.39e-3)" "unprognostic (1.52e-2)" "unprognostic (5.22e-2)" "unprognostic (8.79e-2)" "unprognostic (3.97e-1)" "unprognostic (4.88e-4)" "unprognostic (5.93e-3)" "unprognostic (6.48e-2)" "unprognostic (1.99e-1)" "unprognostic (1.18e-2)" "unprognostic (3.15e-2)" "unprognostic (2.40e-1)" "unprognostic (6.66e-16)" "unprognostic (6.35e-3)" "unprognostic (2.80e-1)" "unprognostic (2.45e-2)" "unprognostic (2.81e-4)" 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 258.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.1 5.7 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 3.4 0.4 0.2 1.6 1.7 1.6 0.2 0.9 0.8 0.1 0.0 2.2 2.3 1.6 0.5 5.1 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 4.3 0.0 0.2 0.5 0.0 0.0 4.1 1.5 0.2 4.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.4 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.9 168.7 0.3 0.0 0.4 0.0 0.0 2.2 0.0 3.1 0.3 1.9 8.8 0.0 1.0 0.0 1.0 0.0 0.2 0.0 0.0 0.0 14.1 0.8 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.4 0.7 0.1 0.1 0.0 7.6 0.0 0.0 0.1 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PGRMC2 "DG6, PMBP" ENSG00000164040 "Progesterone receptor membrane component 2" O15173 4 128269237-128288829 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 274.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041172, HPA058652" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 76000 "Cluster 46: Basophils - DNA binding" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Nuclear bodies, Plasma membrane, Cytosol" "HPA041172: AB_2677345, HPA058652: AB_2683786" "unprognostic (6.16e-2)" "unprognostic (1.35e-1)" "unprognostic (1.41e-2)" "prognostic favorable (3.62e-4)" "unprognostic (6.03e-2)" "unprognostic (6.57e-3)" "unprognostic (2.53e-2)" "unprognostic (2.57e-1)" "unprognostic (1.31e-1)" "unprognostic (8.24e-2)" "unprognostic (9.04e-2)" "unprognostic (3.80e-2)" "prognostic favorable (9.60e-4)" "unprognostic (3.12e-2)" "unprognostic (1.82e-1)" "unprognostic (2.51e-2)" "unprognostic (6.03e-2)" 107.3 51.9 23.8 38.1 25.6 41.7 76.6 25.8 29.8 58.4 34.1 68.1 127.3 52.3 51.3 57.5 44.2 53.4 50.7 25.0 30.2 96.0 173.8 42.7 30.6 25.6 29.6 57.9 74.2 80.5 49.0 85.3 27.7 53.0 65.2 55.1 55.3 73.2 54.4 98.2 121.9 67.4 26.6 32.5 95.8 39.5 28.5 28.0 65.6 44.0 40.8 56.3 51.0 29.8 123.3 44.4 80.3 64.9 339.8 177.6 80.5 164.6 182.7 119.4 158.3 46.4 123.6 86.3 187.8 213.4 138.8 70.1 74.3 81.6 149.3 49.7 42.7 58.0 111.3 88.3 429.1 84.7 41.7 140.9 161.3 100.3 123.3 277.0 109.1 55.0 98.2 105.6 173.7 38.2 78.9 39.2 63.1 148.5 39.7 62.5 64.2 59.8 176.8 42.9 63.3 59.7 92.4 103.1 97.3 131.2 79.7 38.0 203.5 100.0 81.4 103.8 77.3 121.0 106.0 91.3 109.9 74.4 70.1 2.2 1.0 2.0 1.5 0.9 0.7 1.2 1.8 1.5 0.6 0.9 1.6 1.5 0.9 1.1 0.7 2.4 2.0 0.6 23.8 25.6 25.8 29.8 25.0 30.2 25.6 29.6 27.7 26.6 28.5 29.8 95.9 54.5 41.0 16.6 27.0 100.1 49.7 27.8 54.1 22.4 49.2 32.8 60.7 58.6 35.9 44.1 10.4 85.4 41.2 68.2 29.4 57.3 80.9 42.2 59.1 50.0 35.5 104.2 20.4 74.2 146.6 69.9 53.0 64.2 12.0 31.0 47.2 125.1 35.3 11.8 19.1 67.8 40.7 15.7 39.5 49.5 46.3 22.1 67.6 13.1 19.0 98.6 21.6 13.6 25.0 69.7 50.6 37.6 48.9 58.0 177.3 111.0 27.4 41.1 13.1 63.3 53.1 33.3 27.3 51.9 111.8 274.9 32.4 39.4 58.8 34.4 PHACTR1 "dJ257A7.2, KIAA1733, RPEL1" ENSG00000112137 "Phosphatase and actin regulator 1" Q9C0D0 6 12716554-13287843 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Protein phosphatase inhibitor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;brain: 52.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1954.8;Inhibitory neurons: 523.7" "Cancer enriched" "Detected in many" 5 "melanoma: 10.2" "Group enriched" "Detected in many" 6 "basal ganglia: 52.1;cerebral cortex: 27.3;hippocampal formation: 14.8" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 37.8" "Group enriched" "Detected in many" 18 "B-cells: 13.6;dendritic cells: 37.8;granulocytes: 18.7" "Cell line enhanced" "Detected in many" "HMC-1: 74.6;SK-MEL-30: 79.5;U-266/70: 176.1;U-266/84: 133.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029755, HPA029756, HPA029757" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA029755: AB_10600089, HPA029756: AB_10601852, HPA029757: AB_10669870" "unprognostic (7.86e-2)" "unprognostic (7.49e-2)" "unprognostic (2.74e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (7.72e-2)" "unprognostic (4.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-4)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (5.00e-2)" "unprognostic (1.16e-1)" 5.1 2.0 4.3 12.6 52.1 38.0 1.5 0.0 27.3 1.1 0.0 2.0 2.8 1.1 2.5 1.7 2.4 6.0 18.1 14.8 0.0 7.5 2.6 13.9 14.9 0.0 0.0 1.6 6.0 0.4 4.0 2.6 0.0 1.1 2.0 7.8 1.0 0.7 0.4 3.3 3.0 2.5 0.0 11.2 3.7 1.9 0.0 3.5 1.1 0.7 23.9 4.1 1.0 5.4 0.2 0.3 4.5 0.3 0.0 0.1 14.7 1.5 5.0 4.1 7.7 0.3 0.3 0.9 1.2 0.6 6.4 0.3 0.0 0.2 5.3 17.3 0.6 39.5 0.6 0.2 0.5 38.1 74.6 1.7 0.1 0.0 0.7 0.3 6.2 2.1 18.6 31.1 4.1 0.0 0.4 22.4 5.1 0.0 0.0 17.7 10.2 2.9 2.9 0.5 18.3 5.8 0.1 9.9 79.5 6.1 21.2 8.6 6.8 0.6 1.1 0.0 0.4 176.1 133.7 33.5 2.3 9.8 26.0 0.2 1.3 1.5 0.1 1.1 0.1 9.9 0.1 0.0 6.7 13.6 0.0 0.1 18.7 0.1 0.9 37.8 0.0 0.9 4.3 52.1 0.0 27.3 14.8 0.0 0.0 0.0 0.0 0.0 0.0 5.4 12.6 67.3 48.5 265.1 131.6 3.7 1.4 0.8 1.2 43.5 2.1 3.9 10.4 4.3 8.3 62.5 4.2 1.4 79.4 0.7 31.3 0.7 59.9 5.5 2.8 12.9 1.8 13.7 1954.8 2.9 2.3 8.6 0.5 15.0 81.2 2.7 13.6 1.1 83.1 180.0 523.7 0.2 0.0 138.2 91.5 79.8 4.7 188.5 48.0 114.3 20.5 28.4 6.2 186.5 247.8 0.8 0.2 6.4 59.6 1.0 0.3 1.0 5.1 14.0 0.0 4.0 4.3 2.0 4.8 2.1 3.1 1.9 8.6 6.6 1.0 0.8 PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 164.2;placenta: 83.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA031719: AB_10696055, HPA031720: AB_10670553, HPA031725: AB_10610279" "unprognostic (3.25e-3)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-2)" "unprognostic (8.38e-2)" "unprognostic (3.19e-2)" "unprognostic (9.92e-2)" "unprognostic (7.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.49e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.99e-4)" "unprognostic (3.60e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" 11.6 25.4 7.0 7.8 9.0 7.6 5.5 4.3 5.7 8.1 164.2 8.5 7.5 9.9 3.6 22.0 5.7 8.4 12.4 10.0 4.9 5.9 7.9 15.7 7.8 12.3 10.3 6.5 4.9 13.1 4.0 83.8 15.1 10.3 8.5 2.7 6.0 6.9 4.5 2.7 6.1 9.8 3.5 13.5 12.0 6.5 16.5 2.7 15.5 7.3 6.7 7.6 6.4 4.5 21.9 13.5 3.6 26.6 3.7 8.0 15.3 18.0 27.2 7.7 9.6 23.9 9.5 1.2 47.5 51.7 5.4 6.5 2.0 17.9 9.1 18.1 8.5 35.5 14.7 14.0 6.1 9.1 10.5 11.2 9.8 7.7 24.9 11.8 47.0 6.7 10.2 0.1 12.4 24.0 1.3 2.1 26.8 7.7 3.8 3.3 26.3 0.2 9.3 19.2 5.2 5.2 20.0 26.1 0.3 13.4 9.8 13.1 82.2 34.9 18.2 15.2 11.8 0.2 0.1 0.3 8.6 9.5 3.2 6.0 3.5 6.7 3.3 2.5 12.3 0.4 4.0 4.4 3.3 0.2 2.4 1.6 1.8 3.5 2.7 3.2 5.5 1.9 7.0 9.0 4.3 5.7 10.0 4.9 12.3 10.3 15.1 3.5 16.5 4.5 160.9 214.7 94.5 41.4 11.7 24.2 16.0 19.5 47.3 37.0 14.2 13.8 71.8 32.9 73.2 22.0 2.1 84.7 27.5 58.9 13.7 30.5 10.1 49.6 43.7 158.6 21.6 32.8 55.2 22.5 49.8 144.8 54.6 64.7 38.7 34.9 157.1 27.6 35.4 101.0 133.8 19.2 24.4 121.1 40.2 23.2 103.2 52.5 24.9 77.8 71.7 10.3 15.5 5.5 20.9 49.4 22.3 120.0 10.6 63.3 20.2 24.8 51.1 3.0 98.6 95.9 83.5 3.1 2.3 33.0 17.2 52.5 51.3 127.9 26.3 30.9 PHACTR4 "FLJ13171, PPP1R124" ENSG00000204138 "Phosphatase and actin regulator 4" Q8IZ21 1 28369582-28500364 "Predicted intracellular proteins" Neurogenesis "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 212.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028985 Approved Approved "Plasma membrane,Intermediate filaments,Cytosol" NA Yes "Cluster 27: Non-specific - Gene expression" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "Intermediate filaments" "HPA028985: AB_10602142" "unprognostic (1.55e-1)" "unprognostic (2.61e-2)" "unprognostic (4.50e-3)" "unprognostic (1.73e-1)" "unprognostic (5.27e-1)" "prognostic favorable (1.05e-4)" "unprognostic (9.65e-3)" "unprognostic (8.77e-2)" "unprognostic (2.03e-2)" "unprognostic (1.61e-1)" "unprognostic (1.05e-1)" "unprognostic (1.04e-1)" "unprognostic (2.94e-2)" "unprognostic (3.08e-1)" "unprognostic (4.81e-2)" "unprognostic (3.03e-2)" "unprognostic (2.26e-2)" 7.2 6.5 6.3 8.6 8.1 11.8 10.1 8.2 6.8 13.6 10.2 12.9 9.1 13.7 7.1 33.0 13.2 8.9 8.9 5.8 8.5 14.1 16.3 12.4 7.8 9.1 6.8 13.1 11.7 15.1 4.0 10.4 7.2 11.8 14.1 5.1 11.3 8.2 11.9 16.2 10.3 13.8 5.5 12.0 10.7 8.6 8.0 11.9 12.4 18.3 12.2 9.4 14.8 9.3 26.0 17.2 37.8 27.5 9.6 10.2 5.8 18.1 18.3 38.5 40.0 16.4 28.1 24.5 15.9 21.6 24.3 17.7 26.3 17.4 33.9 18.1 14.9 51.6 28.2 26.5 14.3 31.2 56.7 9.9 16.4 24.7 42.7 14.0 52.0 19.5 26.0 16.9 24.5 8.0 22.3 7.8 28.3 14.0 11.8 23.2 35.7 18.5 20.2 22.8 20.1 26.0 41.0 16.9 20.9 14.9 22.5 11.1 33.3 18.8 34.6 13.4 35.8 12.4 19.7 20.1 18.4 26.2 20.3 1.9 2.0 2.0 3.3 2.0 2.9 1.4 2.6 3.3 2.2 2.2 1.8 2.6 1.4 2.4 3.3 2.6 1.2 1.5 6.3 8.1 8.2 6.8 5.8 8.5 9.1 6.8 7.2 5.5 8.0 9.3 65.9 70.5 49.8 60.7 38.9 38.6 23.6 24.1 46.7 34.6 37.0 35.8 38.5 40.0 53.7 23.9 20.9 17.6 36.7 59.9 17.6 32.4 6.1 125.6 58.6 56.2 49.3 32.2 65.8 36.5 17.3 29.1 35.2 212.6 48.0 38.8 42.5 63.3 22.8 23.5 82.6 57.0 24.4 33.6 32.3 8.5 19.3 40.3 17.8 92.8 33.7 19.8 51.5 117.1 148.1 48.2 33.5 29.7 30.8 24.4 40.0 45.5 63.3 39.8 39.5 45.6 31.0 47.1 39.4 62.1 54.1 15.2 35.7 15.3 50.6 30.9 PHF20L1 "CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B" ENSG00000129292 "PHD finger protein 20 like 1" A8MW92 8 132775358-132848807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025060, HPA028417" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA025060: AB_10599822, HPA028417: AB_10602278" "unprognostic (9.12e-3)" "unprognostic (2.29e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-3)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (2.79e-2)" "unprognostic (7.53e-2)" "unprognostic (9.66e-2)" "unprognostic (1.24e-2)" "unprognostic (8.85e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.83e-2)" 12.1 14.0 8.0 13.5 9.6 24.9 10.9 10.4 11.3 11.6 9.9 9.2 9.4 11.4 10.0 11.6 7.9 10.7 17.5 8.0 6.4 10.7 13.4 10.3 11.8 6.5 6.7 11.3 8.9 15.7 8.7 12.4 6.7 9.9 10.1 12.5 9.6 8.0 16.7 7.7 9.9 11.5 5.7 11.5 9.3 13.5 7.2 25.6 22.7 18.5 12.4 12.8 8.9 9.8 20.9 20.6 33.1 19.1 25.3 29.9 11.9 30.1 23.4 20.2 19.7 11.5 14.0 23.8 25.6 30.3 17.4 12.0 22.5 16.0 24.9 40.4 16.1 25.5 24.3 8.2 26.6 20.7 17.6 22.5 19.4 21.1 31.1 19.5 22.6 37.2 32.1 36.4 30.4 21.0 67.6 9.2 14.7 23.8 27.1 32.6 22.1 20.6 16.5 17.8 81.4 23.8 19.1 13.5 24.5 13.8 26.5 23.0 29.6 32.6 25.9 21.5 29.1 21.5 29.9 30.3 28.8 35.8 29.6 3.5 3.8 7.0 2.1 2.4 2.1 2.1 1.9 2.5 3.6 2.2 2.8 2.2 12.6 3.0 3.6 2.9 2.5 1.5 8.0 9.6 10.4 11.3 8.0 6.4 6.5 6.7 6.7 5.7 7.2 9.8 65.9 25.6 51.6 74.4 51.1 33.6 52.6 48.2 40.9 55.7 40.5 38.0 88.5 25.8 57.2 36.8 43.8 29.7 92.9 35.1 23.5 37.3 81.2 39.8 73.4 55.2 43.7 37.9 133.9 31.3 32.0 51.6 41.8 48.9 60.2 60.1 36.0 33.4 36.6 53.8 192.2 29.0 44.7 39.6 49.3 49.5 40.0 84.2 23.2 83.4 67.5 50.9 78.2 104.5 117.5 40.6 26.4 42.9 66.6 40.4 41.5 25.7 30.8 54.1 46.0 68.1 58.9 115.1 45.9 44.9 36.2 45.0 65.8 61.4 30.9 66.7 PHGDH "PDG, PGDH, SERA" ENSG00000092621 "Phosphoglycerate dehydrogenase" O43175 1 119648411-119744218 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Amino-acid biosynthesis, Serine biosynthesis" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 135.0;Exocrine glandular cells: 136.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD8 T-cell: 25.2" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 975.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003681, HPA021241, HPA024031, CAB068216" Enhanced Enhanced "Nucleoplasm,Plasma membrane,Cytosol" No No 1100000 "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "CAB003681: AB_425928, CAB068216: AB_2665666, HPA021241: AB_1855299, HPA024031: AB_1855300" "unprognostic (2.30e-1)" "unprognostic (2.16e-1)" "unprognostic (1.80e-2)" "prognostic unfavorable (1.48e-4)" "prognostic favorable (1.62e-4)" "unprognostic (9.80e-2)" "unprognostic (1.56e-2)" "unprognostic (1.40e-1)" "unprognostic (5.24e-2)" "unprognostic (4.45e-3)" "unprognostic (8.80e-3)" "unprognostic (5.00e-2)" "unprognostic (2.37e-2)" "unprognostic (1.32e-1)" "unprognostic (1.74e-1)" "unprognostic (1.95e-1)" "unprognostic (1.78e-3)" 51.4 3.0 113.6 9.4 125.3 11.4 30.1 130.7 125.9 46.1 89.1 27.2 7.6 25.4 79.6 56.6 49.3 7.6 22.4 108.8 128.8 40.9 126.0 18.0 14.9 121.8 113.9 46.1 171.1 103.9 23.7 13.2 122.4 52.6 7.0 7.5 156.2 33.5 2.6 92.5 13.3 15.0 117.0 6.5 41.7 40.3 115.8 34.0 29.5 4.3 13.3 35.8 62.9 153.6 156.8 35.2 148.0 444.6 64.9 82.8 286.1 101.0 209.3 132.9 257.6 195.7 28.6 0.1 58.1 270.5 16.6 205.6 216.8 224.6 83.9 1.1 162.1 29.1 151.3 153.3 135.7 214.3 1.7 147.6 338.6 146.8 142.2 83.0 100.1 519.7 71.4 443.9 66.8 380.9 222.8 90.1 440.0 93.3 274.6 228.0 181.1 24.8 9.6 120.4 160.8 146.0 65.9 63.9 975.9 103.9 164.8 505.7 0.9 38.3 172.1 207.3 134.8 294.0 79.9 246.1 456.9 328.2 302.7 5.3 1.1 0.2 4.7 0.3 0.2 11.1 2.4 8.2 5.3 4.0 13.0 25.2 2.2 1.8 0.3 2.6 4.5 6.3 113.6 125.3 130.7 125.9 108.8 128.8 121.8 113.9 122.4 117.0 115.8 153.6 5.3 3.2 12.6 31.6 10.0 51.9 118.1 24.2 42.7 0.7 29.7 38.0 2.1 128.7 12.5 20.2 2.1 49.9 2.2 1.6 135.0 60.2 51.2 15.6 3.8 6.9 1.8 5.5 0.3 136.1 54.0 58.7 8.6 12.2 5.7 30.9 3.6 96.1 9.2 0.0 0.6 3.6 18.3 2.2 4.3 116.9 67.7 6.5 56.9 2.8 11.0 82.4 0.0 14.1 32.3 35.6 2.0 127.9 27.4 62.1 0.2 118.4 24.7 3.4 13.1 11.2 48.8 20.0 19.4 57.5 77.1 25.3 5.9 71.4 3.2 56.8 PHLDB1 "FLJ00141, KIAA0638, LL5a" ENSG00000019144 "Pleckstrin homology like domain family B member 1" Q86UU1 11 118606440-118658031 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 87.2;Late spermatids: 87.7;Oligodendrocytes: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 105.2;ASC TERT1: 105.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037959, HPA038448" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA No "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Vesicles, Cytosol" "Plasma membrane" "HPA037959: AB_10673651, HPA038448: AB_10697390" "unprognostic (7.81e-2)" "unprognostic (8.32e-3)" "unprognostic (1.13e-1)" "unprognostic (9.36e-3)" "unprognostic (8.28e-2)" "unprognostic (1.55e-1)" "unprognostic (4.37e-3)" "unprognostic (1.22e-1)" "unprognostic (3.21e-2)" "unprognostic (1.10e-1)" "unprognostic (1.44e-2)" "unprognostic (1.57e-1)" "prognostic unfavorable (6.36e-6)" "unprognostic (7.09e-2)" "unprognostic (2.42e-2)" "unprognostic (3.69e-2)" "unprognostic (1.44e-1)" 52.6 8.1 39.2 11.5 79.7 0.5 38.9 42.5 66.0 39.1 3.8 23.8 9.2 38.4 2.6 9.1 30.2 21.6 33.0 42.3 49.2 15.8 3.2 26.8 4.6 64.3 64.6 31.9 22.2 4.5 8.8 24.6 56.0 16.7 6.4 1.6 11.1 15.8 13.3 15.1 15.3 18.6 33.4 12.5 14.3 12.0 75.3 3.1 20.3 13.6 2.3 21.9 22.9 133.7 4.8 7.5 28.9 14.2 105.2 105.9 10.1 21.9 26.6 12.7 7.4 11.2 31.8 0.0 40.2 44.3 17.2 18.6 6.6 44.8 2.0 0.7 4.2 8.6 5.7 5.5 27.2 0.0 15.8 55.8 9.6 17.8 12.5 28.3 36.6 0.7 7.5 0.3 16.7 3.4 0.1 0.5 10.2 0.4 3.8 1.1 7.5 0.7 12.5 6.8 6.5 14.5 55.8 4.7 15.6 11.3 20.1 2.7 45.4 25.9 22.9 13.2 18.3 0.2 0.0 0.1 7.5 1.5 29.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 39.2 79.7 42.5 66.0 42.3 49.2 64.3 64.6 56.0 33.4 75.3 133.7 34.4 6.4 13.7 53.2 1.6 18.4 9.2 13.7 14.2 4.0 7.2 19.6 5.6 1.5 6.3 31.3 0.0 1.0 2.5 34.2 0.0 9.4 78.3 11.6 87.2 32.1 8.4 0.0 4.1 4.4 1.5 54.9 11.7 8.6 1.3 25.6 26.4 0.9 5.9 3.3 8.3 20.4 0.0 2.5 34.4 87.7 67.1 8.2 12.4 23.4 2.2 7.6 0.0 67.3 244.5 24.3 29.8 44.4 0.7 4.2 10.7 7.8 0.5 2.3 39.5 42.9 53.8 21.9 10.1 1.9 9.1 1.5 5.4 11.0 16.8 2.4 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PHLDB3 FLJ40193 ENSG00000176531 "Pleckstrin homology like domain family B member 3" Q6NSJ2 19 43474954-43504935 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 42.0;skin 1: 43.5" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 58.0;Urothelial cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" HPA043425 Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA043425: AB_10797142" "unprognostic (2.50e-2)" "unprognostic (4.22e-3)" "unprognostic (3.06e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (5.22e-3)" "unprognostic (4.43e-1)" "unprognostic (1.93e-1)" "unprognostic (2.15e-1)" "unprognostic (3.60e-2)" "prognostic favorable (6.36e-6)" "unprognostic (4.62e-2)" "prognostic unfavorable (4.11e-5)" "prognostic unfavorable (5.77e-4)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (2.37e-1)" 3.7 9.2 6.3 5.6 5.5 3.5 6.4 3.9 6.4 14.4 8.9 6.1 5.0 5.3 1.1 42.0 8.0 6.1 5.7 5.1 7.8 8.1 13.9 5.6 7.7 4.5 3.8 12.7 8.0 4.2 10.5 3.1 5.8 14.8 1.7 0.8 15.6 3.7 3.7 43.5 6.6 1.9 2.8 6.6 6.3 30.1 4.5 6.2 5.0 1.0 6.8 8.2 22.4 11.3 6.9 7.2 3.0 7.4 2.6 5.3 19.1 4.9 4.3 4.8 3.3 7.3 7.2 4.1 15.2 3.0 3.8 8.0 2.1 8.6 0.9 9.9 6.8 4.6 7.4 8.8 6.5 1.8 8.5 4.5 10.7 5.1 3.1 3.7 4.3 10.2 8.3 6.1 2.4 11.0 7.2 0.4 1.8 16.6 5.8 8.3 3.9 2.8 2.3 23.3 0.1 6.4 6.3 13.5 6.2 1.8 9.7 5.8 5.4 3.1 8.2 3.8 4.7 15.8 18.8 4.7 2.9 3.4 5.3 0.2 2.3 0.3 2.4 1.4 1.8 2.2 2.2 1.8 4.4 2.4 3.2 3.0 0.5 1.8 0.1 5.1 2.3 1.7 6.3 5.5 3.9 6.4 5.1 7.8 4.5 3.8 5.8 2.8 4.5 11.3 2.7 0.0 1.7 2.6 17.1 29.1 27.2 11.6 31.9 1.0 10.0 8.0 1.9 8.6 7.6 9.2 0.0 18.5 7.6 7.1 1.9 5.5 11.3 12.9 9.6 4.6 3.0 1.7 5.1 2.4 4.5 7.3 4.6 9.8 5.7 3.2 4.6 12.6 3.6 0.0 7.0 4.3 8.2 2.8 34.7 8.9 3.7 11.2 5.4 11.2 6.7 4.1 7.2 4.0 2.0 2.1 4.7 3.4 11.6 22.0 10.5 8.5 12.7 1.9 6.6 8.6 10.9 28.2 4.8 37.7 38.4 58.0 14.3 4.6 3.7 45.1 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 103.0" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1499.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.1;neutrophil: 426.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 426.7" "Cell line enhanced" "Detected in some" "Daudi: 5.7;EFO-21: 3.2;HDLM-2: 4.1;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Actin filaments" "Plasma membrane" "HPA065025: AB_2732727" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.5 3.4 3.4 19.0 0.5 6.3 3.9 0.4 0.6 0.7 2.9 0.7 0.2 1.0 1.3 2.2 1.8 1.8 7.3 1.3 1.0 2.3 1.6 8.8 6.2 0.3 1.2 0.2 0.6 6.4 7.4 0.8 0.0 0.7 1.2 0.3 3.4 1.3 3.0 0.4 6.9 14.2 0.9 103.0 5.5 0.3 0.7 3.2 0.2 0.9 0.5 6.1 0.0 1.0 0.0 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.1 1.5 0.0 5.7 3.2 0.0 2.1 0.0 0.9 0.3 0.1 4.1 0.1 0.7 0.7 0.2 0.0 0.0 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.7 1.2 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 5.4 0.1 0.1 2.2 0.3 1.7 1.1 0.0 0.1 0.2 0.3 1.5 2.0 0.1 0.2 0.6 171.1 0.4 1.5 0.3 0.1 0.1 0.2 0.4 0.0 0.0 0.2 426.7 0.5 1.8 0.0 0.1 1.1 1.5 3.4 6.3 3.9 1.8 7.3 8.8 6.2 7.4 6.9 5.5 6.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 205.8 0.0 0.0 1.4 0.0 8.6 0.7 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.4 0.0 2.6 0.0 1.4 0.0 0.0 0.3 0.0 1499.6 7.8 0.6 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 11.2 4.5 0.0 0.0 237.6 0.1 0.0 0.1 0.1 PHPT1 "bA216L13.10, CGI-202, DKFZp564M173, HSPC141, PHP14" ENSG00000054148 "Phosphohistidine phosphatase 1" Q9NRX4 9 136848724-136851027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 953.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013584, HPA020952" Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA 590000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Nucleoplasm, Nuclear bodies, Plasma membrane" "CAB013584: , HPA020952: AB_1855331" "unprognostic (7.34e-2)" "unprognostic (9.21e-2)" "unprognostic (7.90e-2)" "unprognostic (1.57e-2)" "unprognostic (3.76e-2)" "unprognostic (2.30e-1)" "unprognostic (4.64e-2)" "unprognostic (1.69e-2)" "unprognostic (3.23e-2)" "unprognostic (1.82e-1)" "unprognostic (1.26e-3)" "unprognostic (5.85e-2)" "unprognostic (9.66e-3)" "unprognostic (1.11e-2)" "unprognostic (2.01e-1)" "unprognostic (3.95e-2)" "unprognostic (8.49e-2)" 71.5 109.2 196.7 54.5 200.5 64.6 62.4 206.2 245.6 76.0 192.2 74.0 54.0 44.7 103.0 70.6 99.3 62.0 267.2 192.3 203.3 82.6 47.9 57.3 57.4 199.3 191.9 65.0 153.4 160.9 85.2 49.8 200.3 89.2 50.5 26.3 144.0 86.6 432.6 45.8 62.9 78.1 198.8 41.6 61.5 56.9 199.1 68.5 86.7 441.5 40.0 71.8 41.4 216.2 53.6 452.5 225.6 199.1 153.4 266.0 412.8 147.6 170.8 158.8 138.6 165.7 138.0 145.1 142.8 168.6 180.0 155.0 51.2 293.9 50.2 116.9 132.5 45.4 276.8 380.3 177.5 82.6 176.4 322.8 248.7 91.8 109.5 145.8 218.8 93.1 102.9 129.7 257.2 328.2 156.9 176.7 216.0 372.5 206.6 106.5 106.6 196.7 255.6 113.3 137.6 132.8 146.7 155.8 75.1 107.0 127.2 226.4 177.0 390.6 130.8 91.5 166.5 60.5 93.4 94.0 174.3 59.7 235.8 38.2 290.0 31.0 197.6 318.4 170.7 241.3 173.9 184.6 321.8 178.9 126.0 175.8 13.7 196.7 231.7 425.4 223.6 324.1 196.7 200.5 206.2 245.6 192.3 203.3 199.3 191.9 200.3 198.8 199.1 216.2 125.7 96.1 159.8 24.8 111.8 150.3 187.7 659.2 204.9 43.9 223.1 317.7 384.8 178.7 326.5 217.0 22.9 322.1 111.8 337.1 747.4 196.1 271.3 122.2 168.1 111.9 265.1 80.2 8.1 252.4 489.5 213.1 140.6 170.3 123.5 367.4 83.6 201.9 286.5 67.3 12.5 370.9 309.3 97.2 197.1 953.5 205.0 133.6 334.4 5.6 273.2 194.7 146.2 10.6 25.0 185.3 359.8 223.4 187.8 257.5 540.1 817.4 250.6 77.7 85.5 137.1 249.6 141.8 143.8 140.3 161.8 264.1 106.4 352.5 336.0 199.5 PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2267.8;lymphoid tissue: 2103.1;vagina: 1595.8" "Group enriched" "Detected in many" 10 "Basal respiratory cells: 5354.5;Club cells: 2170.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 22 "cerebral cortex: 12.0;pons: 7.3;thalamus: 19.0" "Immune cell enriched" "Detected in some" 1021 "neutrophil: 1763.3" "Lineage enriched" "Detected in single" 4377 "granulocytes: 1763.3" "Group enriched" "Detected in many" 5 "EFO-21: 89.3;HaCaT: 109.8;OE19: 103.7;PC-3: 189.9" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 1400000 "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" 6.1 0.7 0.2 101.9 0.5 1.8 8.8 0.2 12.0 180.1 1.2 124.3 1.9 2.3 1.1 2267.8 4.8 56.6 1.7 0.2 0.4 1.5 3.3 32.5 0.4 0.3 0.3 0.7 1.6 0.2 2.8 1.1 7.3 11.7 43.3 0.0 460.8 3.5 0.6 78.6 42.3 7.5 0.3 20.0 9.0 0.5 19.0 90.6 0.8 1.9 2103.1 44.7 1595.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.4 0.0 3.1 2.1 1.4 89.3 0.0 1.1 109.8 0.0 23.2 0.1 1.2 0.0 0.5 6.3 0.9 0.0 0.7 0.0 0.0 21.7 17.8 1.9 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.1 0.2 103.7 189.9 0.0 1.0 0.0 21.9 0.4 0.0 0.0 15.7 2.1 0.1 0.0 0.0 0.0 0.8 1.0 10.9 0.3 0.9 0.3 1.8 0.4 14.3 0.7 0.1 0.3 0.4 1.7 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1763.3 0.0 0.1 0.1 0.1 0.6 0.2 0.5 0.2 12.0 0.2 0.4 0.3 0.3 7.3 0.3 19.0 0.3 0.1 0.0 8.6 0.0 7.4 0.1 4.7 5354.5 0.0 0.0 39.4 8.4 0.2 8.6 2170.2 18.4 0.0 0.2 0.5 375.4 0.0 46.6 0.1 3.7 0.7 3.0 16.6 0.0 0.0 317.3 0.0 0.8 2.6 6.9 4.5 0.0 0.0 0.0 0.1 0.0 0.0 31.8 197.4 0.0 0.4 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.8 219.6 0.0 0.2 29.1 33.9 0.2 152.9 0.0 0.0 0.0 50.5 0.0 0.0 36.2 3.8 0.0 2.5 0.1 154.1 150.4 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 209.1;Inhibitory neurons: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 18.8 21.6 45.2 19.2 61.0 24.1 16.8 2.1 74.4 20.4 9.6 23.7 15.8 24.2 9.9 14.3 19.5 13.5 21.5 65.3 9.0 21.3 25.2 19.1 20.5 14.6 4.8 21.4 18.7 34.5 25.2 17.9 14.5 19.5 14.9 27.7 16.5 16.9 23.6 15.1 22.9 21.9 0.0 21.0 26.0 25.7 8.6 34.3 18.0 15.9 18.0 22.2 16.9 43.3 24.5 20.2 17.4 26.3 48.7 29.1 24.9 21.6 32.6 31.3 30.4 15.9 10.2 45.6 12.6 43.9 30.7 21.1 33.4 20.9 19.0 38.9 50.9 47.1 27.1 18.3 24.3 47.0 36.1 26.2 12.9 26.7 14.7 20.4 25.8 13.8 130.2 37.6 24.6 33.8 41.6 16.0 13.8 43.4 20.6 41.1 38.1 8.5 17.3 38.3 42.6 31.0 28.4 32.6 22.6 24.3 27.6 21.3 26.2 56.4 29.1 21.1 18.5 28.6 31.3 35.8 37.4 33.2 24.1 2.1 3.7 5.3 3.2 3.8 3.1 3.4 3.6 3.9 2.5 3.4 3.6 5.0 5.1 7.0 3.3 8.5 4.3 2.2 45.2 61.0 2.1 74.4 65.3 9.0 14.6 4.8 14.5 0.0 8.6 43.3 13.0 12.8 30.4 65.6 14.7 10.1 6.5 7.6 9.6 35.8 17.2 14.4 30.2 20.0 10.5 7.3 47.9 17.8 21.5 19.7 1.9 9.7 36.5 10.3 17.9 15.5 19.2 12.4 209.1 6.3 19.6 15.6 38.7 15.8 12.0 13.8 11.4 19.7 20.1 37.0 127.4 16.7 10.2 21.0 12.6 25.3 19.9 20.2 10.6 39.4 10.9 23.1 16.5 50.3 88.4 8.9 9.7 24.0 15.5 10.1 23.8 10.3 9.6 25.4 26.3 14.5 19.3 35.3 29.6 14.1 9.8 20.0 15.3 26.1 14.3 8.9 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" 6.4 4.8 2.3 5.8 2.6 9.1 9.0 2.8 2.6 5.5 3.1 7.0 7.5 6.4 11.0 5.7 7.8 6.3 2.8 2.5 3.3 10.3 9.4 6.3 8.2 2.8 2.7 4.7 5.7 10.6 3.9 4.8 2.6 7.7 7.8 7.9 4.3 6.8 1.5 6.1 5.8 5.6 2.7 6.1 7.6 6.5 2.7 6.3 13.3 1.8 8.6 7.5 3.7 3.1 10.5 12.2 5.8 4.1 6.6 13.2 7.8 9.0 19.9 10.4 17.8 5.1 10.3 10.9 10.4 12.9 15.6 18.3 3.3 9.5 8.6 10.4 6.4 10.9 13.6 6.7 11.9 30.8 8.7 12.5 11.4 7.9 10.7 13.8 13.6 9.2 12.2 6.9 15.0 9.1 3.4 12.8 3.1 7.9 4.8 4.9 5.6 24.1 18.4 12.4 2.5 6.2 8.1 12.2 17.3 5.4 11.7 22.2 9.5 13.6 4.3 3.7 18.6 8.1 15.9 8.6 12.4 34.5 10.2 13.6 7.7 3.3 6.2 9.7 7.0 6.0 6.1 6.9 7.0 3.9 4.8 5.5 14.5 5.3 11.4 5.4 6.5 5.5 2.3 2.6 2.8 2.6 2.5 3.3 2.8 2.7 2.6 2.7 2.7 3.1 3.5 9.6 9.5 17.6 27.5 4.6 9.5 14.9 4.6 3.3 5.6 4.2 3.4 1.5 14.9 0.0 12.5 12.4 11.2 4.8 1.9 7.4 26.8 4.3 3.2 4.7 6.6 8.2 18.3 10.9 12.0 6.0 6.1 6.4 8.2 4.6 6.8 4.4 8.6 1.7 17.7 4.1 4.1 7.5 6.7 5.1 1.5 8.8 3.6 12.2 8.4 2.7 11.3 17.1 14.6 6.9 4.0 1.5 3.8 3.4 6.4 9.7 7.9 9.4 6.6 4.8 4.2 5.9 3.8 5.7 4.0 6.6 12.5 4.2 4.0 7.4 PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 323.7;Alveolar cells type 2: 372.2;Club cells: 138.4;granulocytes: 159.0;Oligodendrocytes: 123.2;Respiratory ciliated cells: 145.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" 10.0 10.3 9.8 10.9 14.3 16.9 15.9 49.4 47.1 11.8 3.2 16.2 14.0 11.1 11.9 22.7 8.9 12.6 13.5 13.1 9.6 11.9 18.1 9.9 10.5 4.1 0.1 12.1 15.8 16.0 4.3 17.5 9.6 17.3 18.4 38.9 14.8 7.5 13.4 20.1 13.3 8.9 0.0 10.0 21.1 19.8 11.4 12.3 16.9 10.8 12.8 14.9 7.7 49.7 31.6 19.0 18.4 23.0 23.1 31.4 24.3 32.3 25.7 21.2 24.9 24.4 31.9 36.0 44.0 25.0 18.3 44.6 26.0 27.8 32.9 30.3 16.9 21.6 29.6 19.7 16.8 46.0 24.6 18.5 18.1 21.0 24.5 22.3 27.0 25.3 26.1 50.8 23.3 28.2 22.8 13.5 29.9 25.3 17.3 24.1 35.1 35.7 25.5 48.5 20.8 21.4 42.5 29.0 13.6 50.9 46.1 28.6 29.8 41.0 28.2 15.4 23.5 54.3 53.8 17.4 22.5 25.7 40.9 10.1 7.5 6.1 6.9 6.6 7.2 7.9 7.1 6.9 8.9 8.8 8.0 8.4 9.6 12.1 7.8 10.2 6.5 3.7 9.8 14.3 49.4 47.1 13.1 9.6 4.1 0.1 9.6 0.0 11.4 49.7 8.9 323.7 372.2 52.5 9.7 8.0 8.9 8.4 10.2 7.2 16.3 9.4 10.4 12.8 138.4 11.0 4.2 9.6 14.1 11.6 1.9 11.0 6.4 9.1 16.2 24.7 6.7 16.6 54.5 9.5 11.5 26.6 10.2 11.5 159.0 19.3 10.0 12.0 10.1 6.7 41.3 11.6 10.2 9.2 4.0 6.5 7.2 26.9 3.6 44.0 7.9 7.3 3.1 57.8 123.2 10.9 9.4 3.8 8.2 11.7 5.6 5.0 145.5 6.6 6.6 6.8 6.7 20.7 7.3 17.4 17.0 10.4 18.5 10.5 12.3 12.1 PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA023499: " "unprognostic (4.96e-3)" "unprognostic (3.84e-2)" "unprognostic (5.40e-3)" "unprognostic (7.39e-2)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (8.14e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (4.62e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" 4.5 3.8 1.0 3.9 1.1 2.7 3.9 1.4 1.5 3.2 1.8 4.3 2.6 4.2 2.0 7.4 3.4 1.9 3.7 1.0 1.5 6.5 6.5 3.7 3.8 1.5 1.2 2.5 4.7 2.6 4.0 2.0 1.5 3.3 3.6 1.8 5.0 1.3 8.2 5.8 4.3 2.6 1.1 4.4 4.5 2.8 1.4 2.1 4.1 3.4 3.5 3.6 4.3 1.3 10.8 15.2 9.0 9.2 4.9 4.2 15.0 11.6 6.2 12.2 9.3 11.7 12.2 19.9 3.8 7.9 14.9 15.7 16.5 8.0 16.1 11.3 23.3 14.7 7.3 11.0 3.8 32.2 17.2 5.2 9.6 12.5 5.4 2.5 7.9 6.3 26.9 9.5 8.9 10.1 16.4 11.2 16.5 7.5 13.0 15.3 24.0 18.8 7.6 11.6 20.7 16.7 21.0 8.6 9.3 8.4 27.8 4.7 10.4 21.7 29.1 20.8 26.1 8.8 32.8 22.0 5.2 18.0 19.6 0.8 1.7 0.3 2.0 2.7 2.8 1.5 2.6 2.1 3.5 2.9 3.2 3.1 0.4 2.6 3.5 2.1 1.6 2.2 1.0 1.1 1.4 1.5 1.0 1.5 1.5 1.2 1.5 1.1 1.4 1.3 3.6 3.2 3.1 1.6 4.6 3.4 9.5 4.6 12.5 2.2 4.3 2.9 1.6 10.0 4.2 0.0 0.0 6.1 5.4 2.9 7.9 6.8 0.2 2.4 3.6 4.7 1.2 12.6 2.0 6.4 6.7 3.8 5.1 2.7 0.0 2.3 1.1 6.0 4.5 3.3 2.6 4.0 0.0 3.3 2.2 0.6 2.8 3.5 0.0 0.0 3.1 4.2 1.0 1.5 2.5 7.1 3.6 2.2 4.9 10.2 1.0 4.9 2.8 3.1 0.0 3.7 3.6 3.4 7.4 9.4 6.8 4.1 3.1 3.5 5.6 5.3 PIGX FLJ20522 ENSG00000163964 "Phosphatidylinositol glycan anchor biosynthesis class X" Q8TBF5 3 196639775-196736007 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 87.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 87.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029409, HPA073301" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA029409: AB_10610280, HPA073301: " "unprognostic (8.83e-2)" "prognostic favorable (2.12e-4)" "unprognostic (2.14e-1)" "unprognostic (2.42e-3)" "unprognostic (9.25e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.45e-5)" "unprognostic (1.91e-1)" "unprognostic (3.97e-2)" "unprognostic (1.11e-2)" "unprognostic (3.18e-2)" "unprognostic (4.02e-1)" "unprognostic (1.30e-1)" "unprognostic (1.15e-1)" "unprognostic (1.53e-1)" "unprognostic (1.46e-1)" "unprognostic (2.01e-1)" 10.5 10.3 14.4 10.4 15.6 9.0 9.9 14.7 16.7 7.5 19.5 10.8 9.1 8.3 12.4 10.3 7.9 8.3 9.6 15.2 16.7 12.2 8.2 7.2 7.1 15.1 15.8 6.8 9.0 19.6 12.7 8.3 14.8 12.8 10.1 17.4 9.9 10.5 17.1 10.4 9.1 11.2 16.0 6.8 7.6 6.0 16.2 11.6 9.2 14.1 10.9 8.7 7.6 16.7 39.4 18.7 21.4 18.1 22.7 15.3 12.6 18.1 20.7 19.3 20.5 13.7 25.6 20.3 63.6 15.4 25.1 22.2 19.5 16.6 23.1 18.6 19.6 21.0 12.8 12.6 19.2 20.6 34.6 15.1 25.7 17.1 15.7 16.3 12.7 36.5 11.7 38.6 21.0 30.1 59.2 32.1 12.8 30.7 18.3 31.1 27.6 29.5 24.6 11.5 24.4 29.2 31.8 23.9 29.7 16.9 71.8 20.3 8.2 18.1 9.2 25.6 29.5 57.0 70.4 41.1 20.7 26.9 21.5 39.6 7.5 87.5 3.3 10.8 3.0 4.6 3.1 4.6 7.7 5.5 3.7 3.2 18.8 8.7 11.6 3.3 4.4 4.1 14.4 15.6 14.7 16.7 15.2 16.7 15.1 15.8 14.8 16.0 16.2 16.7 14.2 19.2 16.3 13.7 16.4 17.1 30.1 5.5 31.9 34.9 28.3 19.2 12.6 21.5 8.4 29.5 47.9 21.4 31.6 20.8 35.2 7.9 30.5 17.2 23.5 16.9 15.7 15.8 17.7 5.6 20.9 22.0 9.2 17.9 12.0 19.3 17.5 16.6 20.1 33.7 23.7 17.0 8.2 21.4 25.4 22.7 28.0 18.1 21.4 15.9 25.0 50.0 32.0 12.1 14.5 5.2 12.5 35.0 20.1 33.8 27.1 32.5 10.2 39.1 26.3 23.6 28.1 27.1 36.0 29.3 15.9 11.6 21.2 22.7 25.7 23.0 PIK3AP1 "BCAP, FLJ35564" ENSG00000155629 "Phosphoinositide-3-kinase adaptor protein 1" Q6ZUJ8 10 96593315-96720514 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 83.2;lymphoid tissue: 62.3;salivary gland: 73.6" "Cell type enhanced" "Detected in many" "B-cells: 53.7;Hepatocytes: 70.7;Kupffer cells: 127.0;Macrophages: 89.8;Microglial cells: 60.9;monocytes: 57.4;NK-cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 44.7;memory B-cell: 48.3;naive B-cell: 44.5;non-classical monocyte: 123.0" "Group enriched" "Detected in all" 6 "B-cells: 48.3;monocytes: 123.0" "Cell line enhanced" "Detected in many" "Daudi: 85.3;NB-4: 62.1;REH: 183.5;THP-1: 92.9;U-698: 114.7;U-937: 95.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB026136, HPA038452" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" "Intracellular and membrane" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" Cytosol "Nucleoplasm, Plasma membrane" "CAB026136: , HPA038452: AB_2676019" "unprognostic (2.83e-2)" "unprognostic (4.61e-3)" "unprognostic (7.32e-2)" "unprognostic (1.70e-1)" "unprognostic (1.79e-1)" "unprognostic (1.49e-1)" "unprognostic (4.60e-2)" "unprognostic (1.10e-1)" "unprognostic (2.33e-1)" "unprognostic (1.31e-1)" "unprognostic (1.96e-1)" "unprognostic (2.10e-1)" "unprognostic (5.11e-2)" "unprognostic (1.28e-1)" "unprognostic (4.69e-2)" "unprognostic (5.45e-1)" "unprognostic (1.13e-1)" 8.1 4.5 2.1 51.1 2.0 47.5 4.7 2.4 3.2 2.8 2.7 7.3 6.8 2.1 1.7 2.4 2.2 24.8 2.5 1.9 2.9 11.8 83.2 16.7 61.2 6.5 4.6 6.0 22.8 2.0 1.4 14.1 5.3 2.8 8.6 3.1 73.6 2.4 0.7 1.0 7.7 8.3 4.7 62.3 6.9 3.0 5.7 8.7 4.1 3.1 57.8 15.2 0.6 7.6 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.9 1.2 2.8 1.5 85.3 8.5 0.0 1.3 0.1 17.7 0.0 0.6 48.0 3.0 13.0 0.0 1.7 0.1 36.1 6.7 0.0 0.0 0.1 0.0 0.1 0.0 3.1 0.9 0.1 0.1 0.4 1.1 62.1 0.8 24.3 1.0 183.5 4.3 20.0 0.2 0.1 3.6 2.0 0.2 0.2 1.1 0.3 0.2 92.9 0.0 0.0 2.8 0.1 0.7 0.7 0.2 114.7 0.0 95.2 0.0 6.1 16.0 10.5 13.3 44.7 4.7 48.3 0.3 4.1 12.9 44.5 0.1 3.3 13.5 14.0 123.0 11.3 0.5 14.4 2.1 2.0 2.4 3.2 1.9 2.9 6.5 4.6 5.3 4.7 5.7 7.6 0.5 3.2 3.9 1.3 53.7 1.5 0.1 0.1 0.6 0.6 2.2 2.3 2.6 32.9 2.2 1.8 2.1 0.5 41.5 8.1 1.9 40.0 4.3 0.3 0.1 1.8 1.8 10.3 0.8 29.1 0.9 0.7 0.0 0.2 14.0 0.2 5.7 70.7 47.7 0.0 0.8 2.8 4.1 127.0 32.5 1.0 1.2 89.8 5.4 60.9 57.4 0.2 58.7 1.0 0.3 16.4 21.2 2.2 9.4 0.4 1.6 18.3 1.1 3.4 0.0 0.6 0.8 0.8 0.2 0.3 1.1 2.3 18.3 0.4 3.8 0.3 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIK3R6 "C17orf38, FLJ34500, HsT41028, p87PIKAP" ENSG00000276231 "Phosphoinositide-3-kinase regulatory subunit 6" Q5UE93 17 8802722-8867677 "Metabolic proteins, Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 2.9" "Cell type enhanced" "Detected in some" "Early spermatids: 11.5;granulocytes: 47.4;Hofbauer cells: 7.6;Late spermatids: 20.6;Microglial cells: 7.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "basophil: 21.9;eosinophil: 75.8" "Lineage enriched" "Detected in many" 7 "granulocytes: 75.8" "Cell line enriched" "Detected in some" 8 "HMC-1: 148.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA023077 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA023077: AB_1854909" "unprognostic (4.29e-2)" "unprognostic (8.56e-3)" "unprognostic (9.39e-2)" "unprognostic (5.96e-3)" "unprognostic (2.46e-1)" "unprognostic (5.25e-3)" "unprognostic (4.50e-3)" "unprognostic (2.29e-2)" "unprognostic (3.12e-2)" "unprognostic (3.14e-1)" "unprognostic (2.20e-2)" "unprognostic (1.38e-1)" "prognostic unfavorable (1.50e-6)" "unprognostic (3.45e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-1)" "unprognostic (8.98e-2)" 0.4 0.0 1.1 1.8 1.6 2.2 0.4 0.9 1.1 0.6 0.8 0.8 1.5 0.9 0.1 0.5 0.2 1.2 1.3 1.0 1.1 0.0 0.3 1.2 2.1 1.4 1.5 0.0 0.4 0.1 0.0 0.6 1.6 0.3 0.6 0.0 0.2 0.3 0.5 0.8 2.2 0.7 1.1 2.9 1.0 0.4 1.9 2.1 0.0 0.3 1.5 1.1 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 14.1 0.0 19.4 0.0 0.0 0.0 0.0 148.7 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.1 2.6 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 21.9 7.2 75.8 0.5 9.6 0.4 2.7 0.1 0.3 10.8 0.3 0.1 0.2 1.1 1.5 7.8 0.0 0.0 3.3 1.1 1.6 0.9 1.1 1.0 1.1 1.4 1.5 1.6 1.1 1.9 1.6 0.2 0.0 1.3 0.3 1.6 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.6 0.0 0.0 0.0 0.6 0.2 0.0 0.0 11.5 0.0 0.1 2.6 0.0 0.4 0.6 0.0 0.1 0.2 0.5 0.0 47.4 0.0 0.4 0.0 7.6 0.0 0.5 0.0 0.0 4.4 1.6 20.6 0.0 3.9 1.8 7.5 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.5 0.0 0.1 0.0 1.6 0.1 0.0 0.0 PIP4K2A "PIP5K2A, PIP5KIIA, PIP5KIIalpha" ENSG00000150867 "Phosphatidylinositol-5-phosphate 4-kinase type 2 alpha" P48426 10 22534854-22714578 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 498.1" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 1585.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065440, HPA068771" Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 4900000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Plasma membrane, Cytosol" "HPA065440: AB_2685490, HPA068771: AB_2686030" "unprognostic (1.11e-1)" "unprognostic (2.71e-3)" "unprognostic (1.57e-3)" "unprognostic (4.20e-3)" "unprognostic (1.55e-1)" "unprognostic (8.80e-3)" "unprognostic (1.56e-3)" "unprognostic (7.32e-2)" "unprognostic (1.68e-1)" "unprognostic (7.08e-2)" "unprognostic (1.29e-1)" "unprognostic (1.21e-1)" "prognostic unfavorable (1.46e-4)" "unprognostic (1.52e-3)" "unprognostic (2.51e-1)" "unprognostic (1.38e-1)" "unprognostic (7.92e-3)" 28.4 15.5 162.5 47.8 329.4 44.8 15.0 239.0 239.9 26.5 49.8 17.8 13.2 21.1 11.8 19.8 15.2 32.9 13.5 169.7 193.6 16.5 18.6 25.9 81.2 260.6 273.4 8.8 10.9 24.8 8.5 23.7 271.7 9.3 19.1 15.3 7.8 13.0 5.1 8.3 20.6 31.5 171.8 62.6 19.3 12.5 233.3 60.4 12.8 10.9 88.5 24.1 10.5 498.1 30.2 29.2 33.4 10.8 52.3 70.6 25.3 55.0 58.1 29.1 35.7 27.6 47.2 63.2 19.4 111.0 63.7 10.4 29.2 15.4 29.2 140.5 30.4 118.7 21.6 60.9 92.5 23.1 89.1 35.6 13.7 39.7 38.2 44.6 43.7 83.5 67.4 119.1 54.5 12.5 92.3 20.5 13.7 14.5 20.7 36.9 47.8 86.3 43.0 5.8 6.1 13.9 17.7 9.0 86.4 37.6 7.6 39.1 53.0 22.3 32.8 41.7 33.9 75.1 46.3 45.0 60.5 68.3 17.6 72.6 32.6 104.0 119.5 57.9 164.0 52.1 94.2 139.9 43.7 33.1 62.8 118.2 40.5 144.2 67.3 44.8 75.9 183.4 162.5 329.4 239.0 239.9 169.7 193.6 260.6 273.4 271.7 171.8 233.3 498.1 22.5 3.2 6.7 84.9 43.2 17.6 4.0 2.0 3.4 5.7 12.9 5.5 8.1 14.3 5.6 18.4 2.1 8.6 196.9 3.4 11.7 9.7 22.9 7.4 15.7 29.2 4.9 236.9 65.6 10.7 5.4 19.6 6.6 24.8 22.8 13.4 62.4 8.7 31.8 13.5 62.0 2.9 0.0 98.6 80.0 34.5 16.8 82.8 104.9 142.4 81.3 5.0 159.6 167.9 1585.0 22.1 3.7 10.1 36.4 7.1 1.0 15.6 2.2 9.1 19.7 14.1 30.6 6.1 7.9 3.3 16.9 12.4 130.7 8.5 2.8 6.6 PIP4K2C "FLJ22055, PIP5K2C" ENSG00000166908 "Phosphatidylinositol-5-phosphate 4-kinase type 2 gamma" Q8TBX8 12 57591174-57603418 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RH-30: 130.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028658 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" Cytosol "Nucleoplasm, Plasma membrane" "HPA028658: AB_10601245" "unprognostic (7.84e-3)" "unprognostic (1.51e-1)" "unprognostic (2.42e-1)" "unprognostic (2.77e-2)" "unprognostic (2.49e-2)" "unprognostic (3.37e-2)" "prognostic unfavorable (7.98e-4)" "unprognostic (3.17e-2)" "unprognostic (6.00e-2)" "unprognostic (5.51e-2)" "unprognostic (1.75e-1)" "unprognostic (1.88e-1)" "prognostic favorable (2.06e-6)" "unprognostic (1.87e-1)" "unprognostic (2.16e-1)" "unprognostic (3.27e-1)" "unprognostic (3.42e-1)" 13.6 17.2 18.4 11.6 24.0 26.5 20.0 13.4 32.8 18.4 20.7 24.1 16.0 18.5 81.6 28.2 26.6 16.1 15.0 22.3 11.5 36.0 14.8 19.7 13.5 14.9 13.0 16.0 21.0 39.1 18.7 12.1 16.0 21.6 26.3 29.1 25.6 18.4 14.0 27.1 19.2 15.9 11.9 14.6 39.8 28.1 15.7 11.4 22.4 10.5 18.8 18.2 20.5 20.9 52.0 36.4 14.8 17.6 0.0 0.1 47.0 21.4 40.6 38.7 35.1 46.7 73.4 11.3 44.1 25.6 47.4 46.1 24.2 42.2 30.3 15.9 26.1 20.0 17.5 33.7 32.8 19.3 35.0 12.9 70.0 14.7 26.9 46.4 19.6 12.1 26.8 33.3 20.0 52.6 16.5 16.7 28.1 32.1 31.2 0.5 130.9 17.2 39.6 91.1 23.7 30.0 45.8 30.4 29.7 49.3 83.2 17.8 4.2 18.5 26.1 27.7 22.8 25.1 31.5 25.6 36.0 16.0 32.1 58.8 8.2 25.8 24.3 10.5 16.1 8.7 14.8 18.4 8.6 11.0 13.8 16.7 16.3 16.2 14.6 3.8 19.9 11.0 18.4 24.0 13.4 32.8 22.3 11.5 14.9 13.0 16.0 11.9 15.7 20.9 4.1 9.6 8.6 4.9 6.9 12.4 6.2 11.7 10.8 14.3 13.2 8.0 121.7 12.8 11.9 35.0 18.8 11.3 7.4 33.7 21.5 17.7 25.7 14.2 4.2 8.8 22.2 5.2 28.0 19.7 15.2 5.4 26.0 20.3 3.8 4.0 9.3 12.6 8.9 8.4 11.8 18.4 10.2 6.0 2.2 47.9 6.8 5.7 12.4 2.8 5.9 7.5 5.2 5.0 11.5 40.5 12.8 5.3 9.4 10.1 14.2 13.3 15.3 8.1 19.7 3.8 13.1 12.0 9.0 14.3 12.8 17.4 11.9 5.5 10.4 9.2 PIP5K1A ENSG00000143398 "Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha" Q99755 1 151197949-151249536 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029366 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA029366: AB_10602116" "unprognostic (1.05e-1)" "unprognostic (2.36e-2)" "unprognostic (8.64e-2)" "unprognostic (7.94e-3)" "unprognostic (1.17e-1)" "unprognostic (3.28e-2)" "unprognostic (1.26e-2)" "unprognostic (3.01e-1)" "unprognostic (8.79e-2)" "unprognostic (1.15e-1)" "unprognostic (1.37e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (4.16e-7)" "unprognostic (1.44e-1)" "unprognostic (8.14e-2)" "unprognostic (2.93e-1)" "unprognostic (1.59e-1)" 20.1 19.1 16.0 16.1 17.3 9.7 19.5 17.8 19.2 18.9 20.8 17.2 16.2 18.8 21.1 20.4 18.9 19.7 19.8 16.8 17.3 21.9 18.6 21.8 18.7 15.1 15.7 18.7 13.6 23.0 21.5 25.9 14.7 16.7 15.1 30.1 16.9 14.1 29.2 21.0 16.9 20.3 14.2 19.0 16.6 35.1 16.9 24.7 18.4 25.4 20.1 20.5 17.4 18.4 49.3 37.4 57.7 67.6 37.5 38.8 56.7 63.5 89.3 116.6 103.7 68.7 46.8 43.9 66.8 67.9 52.7 42.0 75.7 42.6 101.2 68.8 54.0 36.0 48.4 33.9 70.1 64.9 43.8 51.1 40.3 72.7 90.7 52.1 48.8 69.4 35.6 36.7 60.4 69.9 63.6 32.4 86.0 38.2 58.3 60.5 50.7 34.1 61.2 27.1 38.6 49.4 87.1 66.6 57.4 96.4 69.2 59.4 47.4 46.6 64.7 42.6 77.0 50.5 93.6 99.3 44.7 18.6 56.6 0.1 3.9 5.7 3.7 4.7 2.8 6.6 3.3 4.1 6.4 3.0 3.7 2.9 8.9 3.9 3.8 6.7 3.1 4.7 16.0 17.3 17.8 19.2 16.8 17.3 15.1 15.7 14.7 14.2 16.9 18.4 11.6 32.1 12.2 43.8 21.3 66.2 23.2 17.0 39.9 34.1 31.3 22.0 18.4 17.2 15.3 31.3 98.0 25.9 18.3 12.7 9.8 13.5 4.9 64.0 26.2 15.6 6.0 12.4 59.6 8.7 29.3 19.8 19.4 71.0 12.0 19.9 14.3 14.3 12.8 26.9 51.2 9.7 18.3 10.7 29.5 4.8 13.4 14.9 12.4 44.0 12.2 12.5 9.2 54.8 64.0 19.4 8.9 10.9 16.8 20.9 21.0 10.1 18.4 43.0 13.1 17.4 20.9 52.1 24.6 38.4 50.0 63.5 15.9 18.4 10.7 39.4 PIRT ENSG00000233670 "Phosphoinositide interacting regulator of transient receptor potential channels" P0C851 17 10822470-10838087 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.0" "Cell type enhanced" "Detected in single" "Astrocytes: 2.6" "Cancer enriched" "Detected in single" 40 "glioma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042337 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "Plasma membrane" "HPA042337: AB_10794795" "unprognostic (2.95e-1)" "unprognostic (2.19e-2)" "unprognostic (7.57e-2)" "unprognostic (6.58e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (2.85e-3)" 0.0 2.5 7.5 1.1 8.7 0.0 0.0 11.5 6.8 0.0 1.7 4.0 1.0 0.0 0.0 0.1 0.2 0.1 0.0 5.4 11.6 0.0 0.0 0.0 0.0 22.4 16.5 0.0 0.0 0.0 0.0 0.0 14.0 0.1 2.6 0.2 0.0 0.0 0.0 0.3 1.9 0.8 11.8 0.0 1.4 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.5 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 8.7 11.5 6.8 5.4 11.6 22.4 16.5 14.0 11.8 24.0 10.8 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PITPNM3 "ACKR6, CORD5, NIR1, RDGBA3" ENSG00000091622 "PITPNM family member 3" Q9BZ71 17 6451263-6556555 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 20.5;Hepatic stellate cells: 27.8;Inhibitory neurons: 24.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 17.7;HeLa: 14.8;hTCEpi: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022432, HPA059005" Enhanced Approved "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA022432: AB_2670936, HPA059005: AB_2683876" "unprognostic (2.97e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.69e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.25e-2)" "unprognostic (6.86e-2)" "unprognostic (3.66e-2)" "unprognostic (3.01e-2)" "unprognostic (2.99e-3)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (2.63e-1)" 1.3 3.1 23.6 1.1 20.7 0.1 1.4 7.3 23.7 3.1 0.0 7.5 1.3 1.9 3.4 17.8 4.3 1.8 1.3 19.1 1.6 2.8 1.4 3.1 0.2 0.0 0.8 26.6 1.7 0.9 2.0 0.1 0.0 4.5 3.7 7.9 4.7 8.9 0.9 17.0 2.7 4.0 0.5 60.8 6.8 4.2 4.6 0.4 2.7 0.9 1.1 1.7 6.4 13.0 9.0 0.9 0.7 0.3 0.1 0.2 0.7 0.6 0.2 0.8 0.6 0.6 6.3 0.2 3.3 0.2 2.4 17.7 0.3 3.7 0.3 0.3 0.6 0.1 14.8 0.2 0.9 0.4 0.6 0.2 50.4 1.0 2.8 4.1 0.4 0.7 0.1 0.0 0.6 0.8 0.1 0.2 1.0 4.5 2.5 0.3 1.9 0.1 1.2 0.1 0.4 0.5 8.1 3.8 0.2 0.3 1.3 0.0 0.3 0.4 3.2 0.6 2.1 0.5 0.2 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 23.6 20.7 7.3 23.7 19.1 1.6 0.0 0.8 0.0 0.5 4.6 13.0 1.5 3.2 16.5 3.6 0.2 5.1 2.2 9.6 2.2 13.5 1.3 1.8 2.0 4.3 11.4 1.8 4.2 0.1 0.2 11.1 0.0 2.2 4.1 10.1 1.0 7.8 1.2 0.0 20.5 0.5 0.0 1.6 4.6 10.3 5.7 1.6 27.8 1.6 0.1 5.0 24.2 3.7 4.1 4.1 0.4 1.8 0.6 0.3 0.0 2.8 0.1 0.6 0.0 0.5 1.6 10.0 5.7 0.0 0.2 2.4 0.6 0.3 7.8 11.9 0.0 12.0 1.9 3.4 1.7 11.5 5.8 0.1 0.7 7.1 6.5 5.2 PKD2L1 "PCL, PKD2L, PKDL, TRPP3" ENSG00000107593 "Polycystin 2 like 1, transient receptor potential cation channel" Q9P0L9 10 100288149-100330264 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.8;lymphoid tissue: 7.9;retina: 13.3" "Cell type enhanced" "Detected in some" "Early spermatids: 14.6;Hofbauer cells: 13.6;Horizontal cells: 60.6;Kupffer cells: 14.4;Late spermatids: 20.1" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "CAB022621, HPA070002" Uncertain Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Actin filaments, Cytosol" "CAB022621: , HPA070002: " "unprognostic (2.67e-1)" "unprognostic (3.66e-7)" "unprognostic (8.07e-3)" "unprognostic (4.38e-2)" "unprognostic (4.70e-2)" "unprognostic (5.31e-2)" "unprognostic (2.19e-1)" "unprognostic (2.85e-2)" "unprognostic (2.01e-1)" "unprognostic (9.25e-2)" "unprognostic (1.55e-1)" "unprognostic (9.37e-2)" "unprognostic (1.49e-4)" "unprognostic (3.00e-1)" "unprognostic (2.05e-2)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" 0.2 0.1 5.4 0.4 5.6 0.9 0.7 4.8 10.8 0.1 4.8 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 5.4 4.9 0.3 1.6 2.3 1.5 4.9 5.2 0.1 0.1 0.0 0.1 0.5 5.1 0.3 1.2 13.3 0.1 0.0 0.1 0.0 0.6 0.0 5.0 7.9 0.0 2.3 5.0 0.9 0.0 0.0 1.7 0.2 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.1 5.4 5.6 4.8 10.8 5.4 4.9 4.9 5.2 5.1 5.0 5.0 5.5 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 14.6 0.0 0.0 0.1 0.0 0.0 2.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 13.6 60.6 0.4 0.0 0.0 14.4 0.0 20.1 0.3 3.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 PKD2L2 TRPP5 ENSG00000078795 "Polycystin 2 like 2, transient receptor potential cation channel" Q9NZM6 5 137887968-137942747 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.2" "Group enriched" "Detected in many" 5 "Early spermatids: 42.7;Spermatocytes: 52.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HeLa: 2.2;Karpas-707: 2.6;U-266/70: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041903, HPA043634" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Cytosol "HPA041903: AB_2677734, HPA043634: AB_2678591" "unprognostic (7.53e-3)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (3.59e-1)" "unprognostic (4.04e-1)" "unprognostic (1.21e-2)" "unprognostic (3.06e-1)" "unprognostic (1.40e-4)" "unprognostic (1.64e-2)" "unprognostic (2.13e-2)" "unprognostic (3.00e-2)" "unprognostic (5.85e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" 0.4 0.9 1.5 0.5 1.7 1.5 0.2 3.2 1.1 0.2 0.3 0.1 0.3 0.3 0.7 0.4 0.3 0.4 1.1 0.8 1.2 0.2 0.1 0.2 0.9 0.7 0.5 0.3 0.8 0.1 0.3 0.2 0.8 0.4 0.2 1.1 0.5 0.0 2.3 0.5 0.2 0.1 0.1 0.7 0.4 8.2 1.1 0.1 0.7 0.8 0.2 0.1 0.2 3.1 0.7 0.5 0.1 0.0 0.1 0.2 0.7 0.2 0.0 0.0 0.0 0.0 1.4 1.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.4 0.6 2.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.2 1.4 0.7 2.6 0.0 0.2 0.5 1.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.4 0.4 0.6 0.1 0.4 0.3 0.2 0.2 0.2 0.4 0.7 0.2 0.5 2.0 1.6 0.1 1.0 0.2 0.8 5.3 0.9 1.8 1.0 0.6 0.5 1.5 0.8 0.7 0.5 1.9 1.0 0.9 4.1 1.0 0.6 2.0 0.6 0.6 1.5 1.7 3.2 1.1 0.8 1.2 0.7 0.5 0.8 0.1 1.1 3.1 0.6 3.2 2.2 4.6 4.7 2.2 1.8 0.6 7.4 2.4 0.5 0.4 1.7 0.0 0.9 0.0 0.0 0.4 1.6 0.6 0.0 0.1 42.7 1.5 1.3 1.3 0.0 0.8 5.0 0.0 0.2 1.5 0.5 1.8 1.3 0.5 1.4 0.4 0.3 3.3 5.6 0.0 2.0 0.6 1.9 8.2 0.6 1.3 3.6 1.9 0.1 0.9 1.0 3.5 6.1 0.1 0.0 0.4 1.7 1.5 0.1 0.3 0.0 4.1 0.0 3.2 1.1 52.3 3.1 2.6 1.1 0.1 3.1 0.8 0.2 0.8 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 59.2 45.1 47.1 40.4 50.3 66.8 49.0 44.6 52.4 46.6 44.2 72.4 14.5 61.0 13.6 16.2 48.7 23.9 89.0 40.9 46.3 43.1 25.0 71.1 49.4 53.6 48.4 38.7 52.5 32.8 44.9 33.3 49.8 43.8 9.3 11.5 41.3 30.6 81.7 20.1 45.2 33.0 49.8 90.4 51.4 50.2 49.2 35.6 39.6 53.8 25.8 60.3 32.8 48.5 152.8 88.9 32.3 67.8 51.3 59.8 53.0 53.5 63.5 55.2 52.5 34.9 84.2 144.4 135.0 92.2 68.9 34.4 52.1 23.8 21.2 117.6 67.7 172.8 55.4 75.2 169.1 68.2 103.9 43.3 17.0 33.5 52.2 62.5 129.8 74.9 78.0 96.7 41.4 62.5 104.1 63.2 59.2 54.7 100.0 138.5 43.9 104.7 27.3 24.2 117.3 166.0 33.2 41.7 88.9 15.5 37.8 117.7 196.6 108.8 46.1 133.2 82.8 126.5 123.6 78.9 71.5 135.7 87.4 27.6 27.9 40.6 30.4 38.5 23.3 15.9 20.5 21.1 26.8 16.9 18.6 21.0 32.6 22.1 52.3 17.0 25.7 29.0 47.1 50.3 44.6 52.4 40.9 46.3 53.6 48.4 49.8 49.8 49.2 48.5 78.1 3.2 2.2 17.3 35.3 3.7 6.4 1.9 1.8 37.2 17.6 14.7 4.0 27.1 3.1 35.0 16.7 2.8 77.9 4.9 1.9 28.2 4.9 27.0 25.4 49.4 40.2 17.7 3.6 30.1 14.5 20.8 30.1 20.7 2.5 80.9 53.2 11.3 59.8 48.8 8.6 10.9 8.2 69.0 17.0 8.4 19.9 56.2 17.8 17.8 48.2 61.2 102.0 7.5 11.9 64.2 10.6 23.0 27.1 12.7 1.1 15.2 12.4 29.2 26.3 21.7 29.2 9.3 42.2 1.3 2.7 3.7 55.5 34.3 4.8 4.9 PKN2 "Pak-2, PRK2, PRKCL2, STK7" ENSG00000065243 "Protein kinase N2" Q16513 1 88684222-88836255 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Cell adhesion, Cell cycle, Cell division, Cilium biogenesis/degradation, Host-virus interaction, Transcription, Transcription regulation" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 80.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 80.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034861, HPA057913" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Intermediate filaments,Centrosome,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 15: RT4 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Intermediate filaments" "Nuclear bodies, Plasma membrane, Centrosome, Cytosol" "HPA034861: AB_2674363, HPA057913: AB_2732617" "unprognostic (7.52e-2)" "unprognostic (1.46e-1)" "prognostic favorable (5.67e-4)" "unprognostic (5.95e-2)" "unprognostic (3.39e-2)" "unprognostic (2.51e-2)" "unprognostic (4.64e-3)" "unprognostic (1.38e-1)" "unprognostic (4.43e-2)" "unprognostic (1.27e-2)" "unprognostic (2.90e-3)" "unprognostic (1.23e-1)" "unprognostic (1.51e-2)" "unprognostic (5.98e-2)" "unprognostic (2.38e-1)" "unprognostic (1.01e-2)" "unprognostic (1.99e-1)" 19.3 16.5 9.3 17.6 14.2 48.7 24.1 20.7 10.9 16.4 17.0 23.9 30.5 23.6 25.0 24.7 18.1 17.1 14.1 9.5 9.7 16.9 20.5 20.4 18.2 12.3 10.4 31.2 15.5 22.3 10.1 24.7 12.7 20.3 30.0 26.7 16.3 15.4 9.8 20.3 30.8 18.5 10.1 19.0 20.9 10.5 12.6 17.8 26.1 13.4 17.4 21.3 15.4 17.6 61.1 23.8 45.2 27.3 29.8 33.6 29.6 35.3 32.2 38.5 39.8 25.3 42.5 23.9 41.0 33.6 47.3 46.7 44.7 26.6 52.4 8.6 33.0 17.7 49.3 21.4 26.2 17.6 5.1 27.7 27.1 30.2 36.3 30.6 44.7 18.6 29.9 16.8 42.2 12.2 20.5 15.2 22.8 23.1 27.1 19.3 68.8 9.8 34.3 117.9 22.0 14.5 52.7 29.8 45.7 33.9 22.5 15.7 42.2 32.5 29.2 42.1 37.2 9.2 8.6 16.6 13.6 17.1 12.6 15.3 9.9 16.6 5.7 5.9 5.1 8.0 5.1 5.3 5.0 9.3 6.6 5.6 80.5 3.5 8.0 8.6 4.6 2.7 9.3 14.2 20.7 10.9 9.5 9.7 12.3 10.4 12.7 10.1 12.6 17.6 104.7 41.7 57.8 102.5 52.5 48.4 44.3 33.3 75.1 85.4 60.2 67.9 50.8 38.6 47.9 69.9 89.6 42.9 48.1 101.5 11.7 61.2 2.6 63.7 68.7 59.5 44.3 57.7 134.2 60.7 33.1 53.1 85.6 84.6 15.8 107.0 47.5 39.4 24.2 65.6 130.8 64.3 32.6 35.8 27.9 6.6 54.3 44.9 32.0 178.0 57.3 50.5 22.6 117.1 146.4 77.6 98.1 48.2 54.8 64.7 84.0 26.7 49.1 150.5 39.5 62.8 55.5 43.6 34.6 83.0 52.4 37.4 44.8 90.2 65.0 124.2 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PKP2 ENSG00000057294 "Plakophilin 2" Q99959 12 32790755-32896777 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 188.2" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 393.9;Distal enterocytes: 105.5;Extravillous trophoblasts: 185.9;Undifferentiated cells: 135.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 8.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 198.8;OE19: 72.7;SuSa: 149.0" "Region enriched" "Detected in many" 4 "hippocampal formation: 20.2" "Low region specificity" "Detected in all" "HPA014314, CAB037336, HPA056908" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Cell Junctions" Nucleoplasm "CAB037336: , HPA014314: AB_1855451, HPA056908: AB_2683272" "unprognostic (1.89e-1)" "unprognostic (1.70e-2)" "prognostic favorable (8.55e-4)" "unprognostic (2.55e-1)" "unprognostic (1.13e-1)" "unprognostic (3.88e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.79e-4)" "unprognostic (2.90e-1)" "unprognostic (1.83e-2)" "unprognostic (5.94e-3)" "unprognostic (2.22e-1)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (2.41e-2)" "unprognostic (3.76e-2)" 5.5 2.6 1.6 6.5 2.0 5.8 11.2 3.1 3.8 20.3 8.2 49.8 23.6 5.0 3.9 5.3 73.0 7.4 188.2 8.7 1.0 7.8 25.9 1.3 4.5 1.4 0.3 15.1 16.4 33.6 9.9 20.5 0.6 9.1 45.2 2.6 58.5 6.9 6.0 2.9 26.5 5.5 0.7 2.0 17.8 6.4 1.6 12.4 0.3 1.7 10.6 5.3 3.4 1.6 56.5 10.8 0.4 0.3 0.2 0.0 0.5 0.0 0.0 0.2 0.1 198.8 49.6 0.0 32.9 0.0 7.1 48.8 6.8 43.3 0.0 0.2 15.7 0.3 2.3 52.6 29.5 3.1 0.6 0.2 40.2 0.1 46.2 21.4 1.8 0.1 10.4 15.3 4.8 14.9 0.2 0.4 29.7 72.7 9.5 0.0 23.6 16.8 14.3 26.3 5.9 5.3 2.3 11.4 0.1 149.0 24.7 0.7 0.3 0.1 21.1 0.0 13.5 12.6 0.2 0.4 0.1 0.2 2.6 5.8 0.9 8.1 0.2 1.1 0.6 0.1 0.4 0.3 2.9 0.3 0.5 0.3 0.6 1.0 1.7 0.5 0.4 0.4 1.6 2.0 3.1 3.8 8.7 1.0 1.4 0.3 0.6 0.7 1.6 1.6 0.4 0.0 0.0 0.3 2.2 7.0 48.1 20.7 32.5 3.2 22.1 13.1 393.9 21.5 17.7 1.8 4.2 57.9 0.9 105.5 3.9 12.7 4.0 61.2 11.6 3.7 27.1 2.1 1.3 10.1 185.9 12.9 43.3 52.1 4.5 23.2 5.0 46.0 8.6 1.7 58.8 67.0 26.4 17.0 20.4 1.8 11.8 28.6 10.6 4.7 1.4 14.3 0.0 2.0 1.0 23.6 65.5 2.2 1.6 32.8 30.8 11.0 14.2 1.1 0.0 13.0 9.8 6.9 5.7 12.1 3.3 41.5 2.7 1.0 135.6 28.2 PKP3 ENSG00000184363 "Plakophilin 3" Q9Y446 11 392614-404908 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 294.4;skin 1: 223.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 345.0;Extravillous trophoblasts: 176.8;Paneth cells: 248.9;Proximal enterocytes: 195.6;Undifferentiated cells: 142.9" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 151.3;CAPAN-2: 102.6;HaCaT: 199.1;hTCEpi: 126.9;MCF7: 94.9;SK-BR-3: 148.0" "Region enriched" "Detected in single" 37 "cerebellum: 8.9" "Low region specificity" "Detected in all" "CAB012993, HPA062937" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Nucleoplasm "CAB012993: AB_2533221, HPA062937: AB_2684908" "unprognostic (4.74e-2)" "unprognostic (5.28e-2)" "unprognostic (4.45e-2)" "unprognostic (2.25e-2)" "unprognostic (1.58e-2)" "unprognostic (1.57e-1)" "unprognostic (8.88e-3)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.25e-1)" "unprognostic (6.73e-3)" "prognostic unfavorable (3.93e-4)" "unprognostic (3.55e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (2.16e-2)" "unprognostic (3.41e-1)" "unprognostic (2.60e-1)" "unprognostic (3.15e-2)" 1.1 0.1 0.3 3.7 0.2 0.0 9.1 0.2 0.6 50.2 0.1 34.3 31.1 1.4 4.7 294.4 7.5 4.9 0.8 0.3 0.3 4.2 0.8 9.7 0.1 0.6 0.2 0.3 27.4 9.1 15.8 10.9 0.6 19.8 10.2 0.0 52.8 5.0 1.0 223.0 28.6 0.5 0.2 0.2 29.1 0.7 0.3 2.5 12.8 0.1 8.8 9.2 104.3 0.3 151.3 28.8 0.0 0.6 0.1 0.2 60.3 1.2 1.0 3.1 1.6 59.2 102.6 0.1 6.0 1.1 6.4 199.1 0.0 75.1 0.5 0.1 36.9 0.1 18.0 41.7 0.6 0.0 0.3 0.5 126.9 0.5 30.8 0.5 0.5 0.0 45.3 0.9 0.4 94.9 0.5 0.2 0.3 75.6 49.1 0.8 0.3 0.6 1.6 29.9 41.1 0.7 42.7 148.0 0.2 1.8 53.8 0.4 5.4 1.0 5.2 2.7 0.8 0.2 0.4 0.1 1.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.2 0.2 0.6 0.3 0.3 0.6 0.2 0.6 0.2 0.3 0.3 0.2 16.0 13.0 0.0 1.1 72.1 52.0 56.1 54.7 0.2 27.7 26.5 1.1 11.5 36.8 12.9 0.0 133.8 0.4 345.0 0.0 83.8 0.0 16.1 1.8 1.8 21.7 0.0 0.2 62.9 176.8 2.3 91.3 27.4 13.4 0.4 0.0 0.3 13.2 0.0 0.0 95.1 36.7 0.3 6.5 0.4 0.9 0.9 1.8 0.0 2.0 0.6 0.0 0.0 0.0 140.2 248.9 0.0 0.2 63.5 195.6 0.9 17.9 0.2 0.0 0.0 2.8 0.2 1.7 114.1 88.7 109.7 1.6 0.0 142.9 60.4 PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 261.0;Inhibitory neurons: 260.9;Oligodendrocyte precursor cells: 235.3;Oligodendrocytes: 864.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: AB_2685696, HPA070648: AB_2686291" "unprognostic (2.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.48e-2)" "prognostic favorable (5.80e-4)" "unprognostic (2.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (9.53e-2)" "unprognostic (1.82e-2)" "unprognostic (9.69e-2)" "prognostic favorable (3.29e-7)" "unprognostic (2.23e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-3)" 13.4 6.5 165.2 6.7 229.0 8.3 26.2 186.6 212.7 31.9 89.3 12.6 12.4 14.0 14.2 17.8 19.6 15.3 22.1 130.2 179.5 57.0 16.8 12.6 6.0 256.9 217.1 13.3 15.1 18.1 9.6 6.2 213.7 12.9 13.4 18.5 34.0 20.9 8.2 16.1 11.3 14.3 222.9 6.1 13.8 10.3 194.1 16.1 30.4 9.8 10.1 16.5 12.4 239.5 36.9 21.8 26.7 30.4 12.1 13.4 25.7 29.1 15.9 44.5 38.4 72.4 32.5 23.4 21.5 35.4 16.0 29.0 35.2 29.8 74.1 35.4 19.2 21.2 23.5 56.3 20.9 34.4 4.6 5.7 28.1 30.0 46.3 26.7 23.0 28.9 30.1 33.3 34.7 42.6 15.2 14.3 28.8 51.4 15.9 20.6 40.2 19.3 64.6 26.6 46.2 8.2 20.3 30.4 24.5 24.9 34.7 31.3 10.6 25.9 29.2 19.3 38.2 19.8 18.0 17.0 14.8 19.2 25.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.2 0.1 0.0 0.4 0.1 0.4 0.0 2.0 0.2 0.7 0.2 165.2 229.0 186.6 212.7 130.2 179.5 256.9 217.1 213.7 222.9 194.1 239.5 59.8 41.7 18.9 28.7 3.1 27.0 21.3 23.5 34.1 44.5 44.3 35.9 49.7 38.6 28.7 47.8 29.2 0.2 3.5 17.7 23.5 21.3 14.6 21.0 12.2 71.1 9.0 24.6 261.0 18.1 0.3 15.3 26.0 38.5 10.1 11.8 23.2 28.6 3.1 5.0 260.9 16.6 16.2 7.6 10.0 9.2 10.8 6.2 7.2 163.9 4.5 8.6 2.1 235.3 864.7 17.4 16.7 17.0 5.2 44.6 12.4 33.1 29.0 19.2 13.1 11.4 13.9 15.4 6.3 30.4 30.4 0.3 5.0 15.5 19.4 26.8 PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 19.1;skin 1: 16.1;vagina: 22.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Glandular and luminal cells: 1.1;Ionocytes: 2.0;Prostatic glandular cells: 3.0;Rod photoreceptor cells: 1.0;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 2.0;melanoma: 1.8;prostate cancer: 1.3;urothelial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "RPMI-8226: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 35: Glandular cells - Unknown function" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.3 5.2 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.2 19.1 0.0 0.2 0.8 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.4 22.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 15.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.4 0.0 3.4 0.0 0.0 0.0 0.1 0.4 PLAA "DOA1, FLJ11281, FLJ12699, PLA2P, PLAP" ENSG00000137055 "Phospholipase A2 activating protein" Q9Y263 9 26903372-26947242 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Neurogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005035, HPA020994, HPA020996" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 12000000 "Cluster 14: Monocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 5: NTERA-2 - Transcription" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "CAB005035: AB_562036, HPA020994: AB_1855444, HPA020996: AB_1855445" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (4.00e-3)" "unprognostic (5.00e-1)" "unprognostic (1.61e-1)" "unprognostic (4.06e-2)" "unprognostic (4.50e-3)" "unprognostic (2.48e-1)" "unprognostic (5.54e-2)" "prognostic favorable (7.87e-4)" "unprognostic (3.24e-2)" "unprognostic (1.44e-1)" "unprognostic (9.29e-3)" "unprognostic (1.86e-2)" "unprognostic (6.68e-2)" "unprognostic (1.39e-2)" "unprognostic (5.10e-1)" 16.0 16.9 8.5 16.2 9.0 42.0 12.6 9.3 11.2 11.3 9.6 15.2 13.6 17.5 13.4 18.8 9.8 13.0 18.8 9.5 9.7 15.4 21.5 12.8 15.0 8.1 8.3 11.0 12.0 16.9 8.0 16.0 9.0 12.9 15.9 14.1 10.9 12.5 50.3 12.1 12.6 19.3 8.3 13.3 12.7 20.4 8.1 18.0 15.9 29.1 18.1 14.7 11.2 10.2 64.6 37.0 46.1 46.3 30.4 38.2 34.6 58.4 33.1 43.9 42.2 13.1 29.8 56.9 48.0 45.0 30.6 25.1 45.8 46.0 47.7 75.7 19.1 35.2 57.9 25.5 30.9 28.8 46.3 34.4 27.0 53.2 38.8 33.0 44.3 41.7 22.1 56.6 47.6 26.6 56.3 28.1 66.8 33.2 31.6 39.4 28.7 34.4 33.5 37.6 29.2 49.9 31.3 36.5 19.1 44.8 25.5 22.5 54.3 0.2 53.8 28.5 48.3 18.4 43.7 59.5 30.8 40.4 23.4 21.9 12.7 21.0 11.0 18.2 12.6 14.3 11.5 11.4 13.1 11.9 10.3 12.0 11.4 14.9 21.2 6.6 18.0 9.6 8.5 9.0 9.3 11.2 9.5 9.7 8.1 8.3 9.0 8.3 8.1 10.2 10.8 16.0 11.2 18.3 18.8 11.0 11.3 14.6 17.1 9.1 7.5 6.6 23.8 5.7 16.1 9.2 0.0 24.9 14.9 11.9 9.8 17.6 27.7 10.2 12.3 17.1 9.6 25.9 31.9 16.2 26.6 11.5 15.8 14.7 40.6 13.2 12.5 10.7 20.7 5.0 30.8 8.6 14.2 15.8 8.2 6.6 8.7 17.5 1.8 21.5 15.9 9.5 16.5 24.6 32.1 15.2 8.7 8.2 23.1 10.6 11.0 12.3 12.7 6.7 19.7 13.0 34.1 28.1 24.9 20.9 9.5 49.3 18.3 21.5 12.6 11.6 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.3" "Cell type enhanced" "Detected in many" "Astrocytes: 563.5;Excitatory neurons: 2569.1;Inhibitory neurons: 1774.0;Oligodendrocyte precursor cells: 783.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 74.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 45.5;Hep G2: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" NA NA 6600 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: AB_2674311, HPA057910: AB_2683552" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 9.3 8.9 11.7 5.7 52.3 4.8 7.6 0.0 74.3 8.2 0.0 18.1 7.2 9.3 3.5 5.4 9.6 8.5 11.7 17.4 0.0 13.2 4.3 5.0 1.8 0.0 0.1 3.7 14.7 44.3 4.3 19.6 0.0 13.4 4.1 7.1 29.0 18.8 14.4 2.6 5.7 8.1 0.0 3.6 8.0 3.0 9.8 6.8 3.8 11.0 0.9 15.9 6.7 23.8 0.2 1.2 4.8 0.3 8.7 16.1 6.3 20.2 13.1 5.2 3.1 45.5 5.0 2.2 8.2 3.9 0.3 0.0 3.7 0.0 3.8 0.0 4.4 1.0 3.5 68.7 2.2 1.1 0.7 1.1 0.8 7.1 0.0 6.5 10.6 13.0 7.1 26.0 0.1 6.2 1.0 3.3 15.0 10.6 6.6 14.7 0.0 12.1 4.0 16.8 16.9 7.2 0.1 4.1 0.9 17.1 19.9 6.6 1.9 16.8 7.5 1.3 12.7 19.4 24.5 33.9 8.6 12.6 29.5 0.3 1.3 1.2 1.4 0.3 2.0 0.1 0.4 0.5 0.1 0.2 0.2 0.4 0.8 1.1 0.1 0.3 0.1 0.2 11.7 52.3 0.0 74.3 17.4 0.0 0.0 0.1 0.0 0.0 9.8 23.8 74.8 0.0 3.4 563.5 1.1 1.9 20.8 2.3 8.0 7.6 8.1 23.2 26.9 7.2 2.6 16.5 0.0 2.4 16.8 1.3 33.2 1.2 9.9 42.1 5.1 54.6 0.0 6.5 2569.1 13.4 2.8 25.8 3.6 83.6 1.3 0.2 26.4 2.8 0.8 1.7 1774.0 2.1 0.0 8.2 1.2 4.3 3.4 9.1 7.2 211.7 12.2 18.2 15.5 783.1 34.8 1.8 0.5 3.8 6.1 20.2 0.1 9.4 9.9 4.1 0.0 7.4 13.3 4.7 5.6 2.5 1.7 1.8 15.4 1.1 1.2 18.9 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLCD4 ENSG00000115556 "Phospholipase C delta 4" Q9BRC7 2 218607855-218637184 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Guanine-nucleotide releasing factor, Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "retina: 166.0;skeletal muscle: 114.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 139.9;Cone photoreceptor cells: 246.0;Rod photoreceptor cells: 176.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SH-SY5Y: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009914, HPA038139, HPA038140" Enhanced Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Endoplasmic reticulum, Plasma membrane" "CAB009914: AB_2252306, HPA038139: AB_2675855, HPA038140: AB_2675856" "unprognostic (2.11e-1)" "unprognostic (1.72e-1)" "unprognostic (1.76e-2)" "unprognostic (5.65e-5)" "unprognostic (7.77e-2)" "unprognostic (1.45e-2)" "unprognostic (7.06e-3)" "unprognostic (2.86e-2)" "unprognostic (3.15e-1)" "unprognostic (8.87e-3)" "unprognostic (7.54e-5)" "unprognostic (3.28e-2)" "unprognostic (2.49e-1)" "unprognostic (1.86e-1)" "unprognostic (6.32e-2)" "unprognostic (8.46e-3)" "unprognostic (3.09e-1)" 1.5 2.7 4.5 0.2 4.4 0.0 1.3 4.5 7.2 1.4 3.5 15.6 0.6 0.6 0.3 4.8 0.6 0.4 1.1 4.5 4.6 10.7 0.6 0.6 0.1 5.6 5.1 0.7 0.5 1.7 9.6 0.2 4.9 4.4 1.7 166.0 2.3 0.3 114.0 1.0 3.3 1.3 4.2 0.3 6.9 9.8 5.0 0.1 1.6 30.4 0.1 20.5 2.0 4.7 0.0 0.9 1.2 0.0 0.3 1.2 1.1 0.0 2.5 0.4 1.3 0.0 0.1 0.0 1.5 0.4 0.4 0.1 0.0 1.5 0.3 0.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 2.8 0.1 1.9 0.5 4.2 2.8 0.1 0.0 0.0 2.3 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.0 0.1 4.3 0.0 1.8 20.2 0.3 0.1 0.1 0.2 2.1 0.0 4.5 0.1 0.0 0.2 0.2 0.0 0.0 0.0 4.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.5 4.4 4.5 7.2 4.5 4.6 5.6 5.1 4.9 4.2 5.0 4.7 0.3 0.0 1.1 7.8 0.1 0.5 0.3 0.9 3.4 139.9 1.5 0.9 1.0 0.0 0.1 0.0 246.0 0.1 0.1 0.0 0.0 0.1 21.4 0.6 0.4 1.5 0.0 0.0 6.7 0.0 13.5 0.7 0.0 1.0 0.0 0.1 0.7 0.0 0.6 8.4 4.9 0.1 0.0 0.0 0.4 33.8 0.3 0.2 0.0 0.0 0.1 9.1 0.0 2.0 2.3 0.7 0.0 0.0 0.0 0.1 0.0 2.2 0.2 176.9 0.0 6.1 1.8 3.6 1.2 0.6 0.1 0.8 0.1 0.0 0.1 0.2 PLEKHA4 PEPP1 ENSG00000105559 "Pleckstrin homology domain containing A4" Q9H4M7 19 48837097-48868617 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Peritubular cells: 53.4;Smooth muscle cells: 48.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 63.4;BJ hTERT+ SV40 Large T+ RasG12V: 49.5;SK-MEL-30: 77.0" "Low region specificity" "Detected in some" "Region enriched" "Detected in many" 6 "spinal cord: 45.0" "HPA042978, HPA048473" Uncertain Approved "Plasma membrane,Cytokinetic bridge,Centriolar satellite,Cytosol" Yes No "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "Cytokinetic bridge, Centriolar satellite" "HPA042978: AB_2678249, HPA048473: AB_2680409" "prognostic favorable (1.97e-4)" "unprognostic (4.39e-1)" "unprognostic (8.16e-2)" "unprognostic (2.85e-2)" "unprognostic (3.98e-1)" "unprognostic (4.20e-2)" "prognostic unfavorable (8.68e-4)" "unprognostic (5.09e-2)" "unprognostic (1.01e-2)" "unprognostic (1.17e-1)" "unprognostic (1.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.84e-2)" "unprognostic (1.35e-1)" "unprognostic (1.67e-1)" "unprognostic (1.08e-3)" "unprognostic (6.38e-2)" 34.0 24.6 8.8 12.1 8.8 0.7 31.7 8.0 9.5 28.7 10.9 43.0 5.6 34.6 5.0 14.3 30.5 11.1 41.4 8.7 10.6 32.4 32.8 25.7 5.8 16.9 14.7 47.5 13.2 9.5 29.9 5.6 10.4 28.3 3.9 2.5 15.1 8.4 19.3 17.2 16.0 10.7 10.8 16.2 21.1 11.0 12.4 5.5 31.0 13.1 3.3 34.4 21.7 10.3 9.0 0.5 9.9 63.4 14.2 41.7 8.0 7.0 24.7 26.8 49.5 5.9 2.5 0.4 11.8 9.8 10.4 2.7 3.5 3.6 4.2 0.0 3.4 2.3 1.7 6.6 11.0 0.0 14.2 21.5 2.2 15.6 1.0 11.1 8.0 11.2 9.5 5.3 7.4 5.4 3.2 0.5 1.5 6.0 0.8 0.3 31.5 0.6 8.3 0.1 0.0 11.0 3.0 2.6 77.0 2.5 3.9 3.0 1.3 8.5 6.8 11.2 1.8 28.3 25.4 5.3 10.2 0.7 23.0 0.0 0.3 0.9 1.8 0.3 1.3 1.7 1.7 1.1 0.1 3.9 2.8 2.6 0.1 0.8 0.3 1.2 0.6 0.9 8.8 8.8 8.0 9.5 8.7 10.6 16.9 14.7 10.4 10.8 12.4 10.3 6.4 0.0 18.7 2.3 1.4 9.6 31.3 17.6 12.0 0.7 11.4 18.3 37.1 17.2 27.2 7.3 0.0 3.3 2.9 3.2 1.9 23.3 0.8 11.6 34.1 7.0 1.2 3.2 0.4 5.1 6.8 41.7 7.7 11.6 0.0 18.8 6.4 13.3 2.9 0.0 0.5 2.5 4.1 0.8 9.2 2.0 41.3 1.9 12.4 1.9 1.3 9.9 2.1 0.5 0.2 6.9 0.5 53.4 0.7 29.8 0.7 14.6 20.5 1.0 6.6 33.0 48.4 4.0 3.7 5.7 9.8 2.9 2.4 16.0 3.3 21.4 PLEKHA6 "KIAA0969, PEPP3" ENSG00000143850 "Pleckstrin homology domain containing A6" Q9Y2H5 1 204218853-204377665 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Distal enterocytes: 66.6;Excitatory neurons: 102.6;Inhibitory neurons: 62.5;Oligodendrocyte precursor cells: 85.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 60.3;BEWO: 94.6;CAPAN-2: 79.2;OE19: 80.9;RT4: 66.4;SK-BR-3: 58.4;T-47d: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028152, HPA028157, HPA054311" Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Vesicles "HPA028152: AB_10601048, HPA028157: , HPA054311: AB_2682446" "unprognostic (9.81e-3)" "unprognostic (3.05e-1)" "unprognostic (1.59e-2)" "unprognostic (3.14e-2)" "unprognostic (1.63e-1)" "unprognostic (1.30e-1)" "unprognostic (2.37e-2)" "unprognostic (1.38e-2)" "unprognostic (9.01e-2)" "unprognostic (3.32e-1)" "unprognostic (9.60e-3)" "unprognostic (1.53e-1)" "unprognostic (5.02e-3)" "unprognostic (1.23e-1)" "unprognostic (8.22e-2)" "unprognostic (5.17e-2)" "prognostic favorable (3.57e-4)" 5.1 6.6 20.4 6.0 21.6 0.4 13.7 20.9 34.4 4.1 9.1 32.2 25.5 4.8 12.9 17.2 9.3 13.2 20.8 19.6 18.7 27.4 27.5 3.2 0.6 23.1 24.3 4.6 10.2 5.7 31.1 8.8 23.3 13.8 29.3 11.4 9.0 13.9 6.0 4.0 29.5 3.8 17.9 3.1 39.7 5.4 34.6 1.0 4.0 2.4 2.4 12.7 7.5 24.1 60.3 36.8 23.7 0.1 0.3 0.6 94.6 2.1 6.6 0.2 0.3 17.8 79.2 0.3 17.3 1.4 0.3 6.7 0.3 6.5 0.3 0.2 3.8 0.2 15.2 25.7 3.5 0.0 0.1 1.0 19.6 0.0 5.0 7.2 10.4 0.8 0.1 0.2 23.9 26.7 0.1 0.1 7.4 80.9 44.6 0.0 0.2 0.1 23.0 66.4 4.8 48.4 26.6 58.4 0.4 4.9 55.3 0.3 0.7 0.0 1.0 0.3 0.5 0.2 0.0 0.1 0.3 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 21.6 20.9 34.4 19.6 18.7 23.1 24.3 23.3 17.9 34.6 24.1 0.2 0.0 10.9 111.0 0.3 0.1 4.2 1.9 0.6 41.6 15.7 8.1 16.6 37.1 4.5 9.2 20.9 6.6 0.5 66.6 3.9 8.4 10.4 4.0 1.3 1.2 16.8 2.7 102.6 5.1 2.4 9.0 40.8 6.2 0.0 0.3 5.0 21.4 0.8 18.5 62.5 32.7 4.1 0.6 0.7 4.0 5.3 0.7 0.0 15.0 0.1 1.2 0.0 85.5 41.8 13.3 33.2 3.8 0.1 6.9 15.2 11.7 7.2 7.1 0.0 26.4 1.1 0.6 0.2 1.4 0.6 21.6 0.6 0.1 34.5 13.7 PLEKHA7 DKFZp686M22243 ENSG00000166689 "Pleckstrin homology domain containing A7" Q6IQ23 11 16777297-17014414 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 111.0;Gastric mucus-secreting cells: 40.8;Microglial cells: 48.7;Oligodendrocytes: 37.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "eosinophil: 3.7;MAIT T-cell: 2.0" "Group enriched" "Detected in many" 6 "granulocytes: 3.7;T-cells: 2.0" "Cell line enhanced" "Detected in many" "CAPAN-2: 116.4;HaCaT: 75.2;OE19: 58.6;RT4: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038610, HPA066103" Approved Enhanced "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Cell Junctions" Cytosol "HPA038610: AB_10671746, HPA066103: AB_2732738" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (3.81e-2)" "unprognostic (4.30e-2)" "unprognostic (2.51e-2)" "unprognostic (6.95e-3)" "unprognostic (2.81e-2)" "unprognostic (1.85e-2)" "unprognostic (2.65e-1)" "unprognostic (1.73e-1)" "unprognostic (2.65e-3)" "unprognostic (3.13e-2)" "prognostic favorable (1.89e-15)" "unprognostic (9.74e-2)" "unprognostic (1.17e-2)" "unprognostic (4.81e-1)" "unprognostic (2.65e-2)" 10.3 1.7 10.0 5.5 11.9 0.6 13.3 9.6 7.0 11.2 26.5 18.3 27.3 4.1 3.8 46.0 9.1 7.3 24.0 7.5 14.3 26.4 16.7 8.0 2.3 11.5 17.9 12.7 15.2 17.6 4.2 9.0 11.8 7.0 16.9 27.4 21.5 5.3 2.2 14.1 25.4 3.6 7.3 1.8 23.7 10.1 21.2 4.0 10.9 2.2 6.6 14.0 18.3 10.3 14.2 12.7 11.9 5.5 0.7 0.0 20.7 0.1 0.4 4.9 9.0 22.6 116.4 0.2 5.4 1.9 0.7 75.2 16.9 0.2 3.5 4.2 16.2 39.7 11.2 13.5 0.3 0.1 0.5 0.6 6.4 0.0 0.4 10.7 0.0 14.3 1.7 0.4 2.0 8.7 8.8 0.3 6.1 58.6 12.4 11.5 0.0 3.0 10.9 109.9 8.3 0.9 16.7 44.3 0.6 22.3 11.3 4.1 3.3 0.2 4.1 3.2 2.8 7.6 2.4 16.2 0.1 0.8 0.1 0.1 0.1 3.7 0.3 0.0 2.0 0.1 0.3 0.2 0.1 0.0 0.1 0.2 0.3 0.1 0.0 0.4 0.0 0.2 10.0 11.9 9.6 7.0 7.5 14.3 11.5 17.9 11.8 7.3 21.2 10.3 8.2 3.2 17.0 111.0 0.6 0.6 1.1 1.4 0.6 2.3 6.9 6.1 8.7 7.2 8.6 11.0 25.0 6.7 0.2 12.0 3.9 6.1 16.3 20.5 2.3 4.7 0.0 1.3 19.3 6.0 0.9 1.0 40.8 22.9 2.5 16.1 2.2 2.9 1.8 0.0 26.2 6.5 0.0 1.0 1.4 6.1 0.6 2.7 0.0 48.7 0.8 4.3 1.0 15.6 37.9 10.7 4.1 0.4 1.8 0.8 9.2 10.6 8.0 9.7 0.0 1.0 1.2 0.5 0.5 12.3 0.4 6.0 1.2 2.1 3.1 6.4 PLEKHG3 "ARHGEF43, KIAA0599" ENSG00000126822 "Pleckstrin homology and RhoGEF domain containing G3" A1L390 14 64704102-64750249 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 179.2" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 90.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 24.0;NK-cells: 9.4;T-cells: 16.2" "Cell line enhanced" "Detected in many" "A-431: 78.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063455, HPA065323, HPA073702, HPA074734" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytokinetic bridge,Centrosome,Cytosol" Yes No "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Nucleoplasm, Cytokinetic bridge, Centrosome" "HPA063455: AB_2685015, HPA065323: AB_2685467, HPA073702: AB_2732238, HPA074734: AB_2732265" "unprognostic (8.71e-2)" "unprognostic (1.69e-1)" "unprognostic (4.38e-2)" "unprognostic (4.04e-2)" "unprognostic (2.18e-1)" "unprognostic (7.22e-2)" "unprognostic (7.21e-2)" "unprognostic (5.53e-3)" "unprognostic (1.49e-1)" "unprognostic (3.34e-3)" "unprognostic (3.63e-1)" "unprognostic (3.54e-2)" "prognostic favorable (7.39e-8)" "unprognostic (2.29e-1)" "unprognostic (2.67e-1)" "unprognostic (4.24e-2)" "unprognostic (2.67e-3)" 25.2 3.5 44.0 10.7 92.5 16.3 23.4 47.2 74.1 33.9 53.0 39.0 13.0 67.5 5.0 45.8 38.1 22.6 17.2 44.5 46.7 36.0 36.3 14.3 5.6 65.8 66.3 33.8 33.0 17.0 6.8 29.3 60.9 24.2 15.5 2.9 29.2 37.5 9.7 44.9 13.2 26.4 37.9 26.6 22.3 5.7 74.1 4.6 23.7 7.4 4.9 32.2 39.1 179.2 78.4 36.5 29.8 45.3 3.1 0.0 49.0 8.7 10.4 13.8 11.0 38.9 34.3 0.0 15.3 8.6 4.8 74.6 20.3 69.7 4.7 0.2 16.7 35.1 48.3 9.2 4.0 1.3 16.1 3.9 39.6 2.9 24.4 22.9 9.1 0.3 0.0 0.4 4.6 37.5 0.1 32.0 10.0 21.2 37.0 0.4 14.7 5.5 37.0 58.0 9.9 18.0 17.7 26.7 25.1 27.5 29.0 8.0 16.6 6.0 59.8 0.3 12.3 0.1 0.2 0.1 0.6 3.7 10.7 9.0 3.0 18.2 16.2 1.5 11.1 0.0 5.0 7.3 1.0 0.0 0.5 3.6 24.0 9.4 1.0 0.0 1.7 5.3 44.0 92.5 47.2 74.1 44.5 46.7 65.8 66.3 60.9 37.9 74.1 179.2 3.1 3.2 6.2 15.0 0.7 19.4 19.4 15.1 21.6 5.5 16.0 9.8 7.8 12.8 6.0 47.8 0.0 7.9 14.5 24.7 11.7 26.7 0.9 18.6 18.5 4.0 34.7 0.4 1.0 20.6 9.5 7.4 14.3 23.6 1.3 1.9 3.6 10.1 5.5 0.0 3.2 26.9 18.3 6.5 8.0 1.5 7.5 2.7 5.4 6.5 4.6 9.1 45.3 10.6 90.9 35.3 16.7 25.6 2.8 16.1 2.3 9.5 4.0 0.8 26.3 5.1 25.3 0.2 1.6 25.6 21.5 2.6 9.0 10.5 13.2 32.2 PLEKHG4 "ARHGEF44, DKFZP434I216, SCA4" ENSG00000196155 "Pleckstrin homology and RhoGEF domain containing G4" Q58EX7 16 67277510-67289499 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 42.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 13.6;Granulosa cells: 13.3;Spermatocytes: 33.2;Spermatogonia: 21.5;Theca cells: 17.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Region enhanced" "Detected in some" "cerebellum: 3.3" "Not detected" "Not detected" HPA055696 Approved "Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Cell Junctions" "HPA055696: AB_2682889" "unprognostic (2.63e-1)" "unprognostic (1.98e-3)" "unprognostic (1.16e-1)" "unprognostic (9.90e-2)" "unprognostic (3.40e-1)" "unprognostic (6.34e-2)" "unprognostic (1.50e-1)" "unprognostic (7.88e-2)" "unprognostic (6.88e-2)" "unprognostic (4.06e-3)" "unprognostic (4.48e-2)" "unprognostic (7.92e-2)" "prognostic unfavorable (6.72e-9)" "unprognostic (1.85e-1)" "unprognostic (6.78e-2)" "unprognostic (9.35e-3)" "unprognostic (5.01e-2)" 7.9 4.6 1.8 3.2 2.6 1.5 9.5 2.6 1.9 6.2 1.3 4.5 4.1 6.0 1.2 4.8 4.0 4.3 1.4 1.8 2.2 3.2 0.4 4.5 4.4 2.8 2.7 17.4 5.8 1.8 3.3 5.1 2.7 2.9 3.0 1.7 6.1 1.7 1.7 9.0 4.4 2.9 2.4 8.4 2.7 42.3 2.6 4.2 4.3 1.9 3.0 3.2 5.7 3.8 6.1 11.4 0.7 6.7 5.7 53.7 8.7 13.9 18.6 13.8 22.7 32.9 5.4 17.1 39.5 13.0 4.7 0.2 8.4 0.8 9.9 3.0 4.5 33.8 30.8 8.2 17.5 20.3 26.2 40.5 6.6 46.3 0.5 11.6 27.5 54.6 27.6 0.4 0.2 4.7 26.0 6.8 5.1 5.0 12.0 0.1 0.1 17.6 6.5 1.4 3.6 20.4 46.9 3.6 19.7 2.1 2.6 14.4 41.9 6.7 24.0 48.8 0.4 39.3 43.0 16.3 27.8 0.6 8.4 0.0 0.0 0.0 0.2 0.2 0.4 0.1 0.2 0.3 0.1 0.0 0.5 0.3 0.0 0.1 0.1 1.1 0.4 0.3 1.8 2.6 2.6 1.9 1.8 2.2 2.8 2.7 2.7 2.4 2.6 3.8 2.7 3.2 2.6 1.0 0.7 2.8 0.6 0.9 3.4 0.8 9.5 13.6 4.2 1.5 3.3 1.8 0.0 0.4 3.1 1.5 0.0 0.9 1.4 0.6 4.1 1.9 1.2 0.8 0.6 0.4 0.4 6.6 1.1 0.6 3.8 13.3 1.4 0.1 0.8 0.0 0.9 2.7 0.0 1.0 0.5 2.7 6.2 0.9 0.0 3.7 0.2 3.2 1.0 0.0 3.6 1.1 2.5 1.5 0.6 1.2 1.2 0.1 1.0 6.5 6.6 4.0 2.4 33.2 21.5 2.0 1.3 0.3 2.7 17.6 4.1 0.5 PLEKHG6 "FLJ10665, MYOGEF" ENSG00000008323 "Pleckstrin homology and RhoGEF domain containing G6" Q3KR16 12 6310436-6328506 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 33.9;intestine: 43.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 117.9;Extravillous trophoblasts: 56.2;Paneth cells: 67.5;Proximal enterocytes: 62.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "plasmacytoid DC: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "BEWO: 153.2;CACO-2: 50.1;CAPAN-2: 27.3;OE19: 48.0;RT4: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041459, HPA058230" Uncertain Supported "Cell Junctions,Centrosome" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" Centrosome "HPA041459: AB_10794518, HPA058230: AB_2683645" "unprognostic (1.67e-1)" "unprognostic (9.93e-3)" "unprognostic (1.44e-1)" "unprognostic (8.03e-3)" "unprognostic (5.84e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.20e-2)" "unprognostic (1.22e-1)" "unprognostic (3.13e-1)" "unprognostic (3.68e-2)" "unprognostic (1.72e-1)" "unprognostic (6.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.44e-1)" "unprognostic (4.18e-2)" "unprognostic (5.73e-2)" 15.1 0.3 1.3 4.3 1.2 2.7 12.8 1.5 2.0 7.5 2.1 31.0 36.5 0.5 0.5 33.9 1.0 5.0 0.3 1.0 0.9 2.7 4.5 1.3 0.6 1.4 1.4 0.2 5.6 7.9 5.2 8.5 1.0 3.0 17.9 0.2 13.3 1.3 0.4 12.1 43.4 1.1 0.7 0.5 11.0 0.8 1.3 0.7 3.9 0.2 2.5 15.7 15.0 1.5 0.7 6.0 0.8 0.1 2.9 0.2 153.2 0.3 0.0 0.4 0.3 50.1 27.3 0.3 0.4 0.0 0.2 13.0 0.0 0.4 0.2 0.1 0.1 0.2 1.5 10.2 0.5 0.5 0.4 0.0 0.7 0.2 0.0 0.5 0.1 0.2 0.4 0.3 0.0 7.9 0.0 0.7 12.7 48.0 1.0 0.2 0.2 0.3 0.1 53.2 0.3 0.2 1.2 23.1 0.3 10.9 7.5 0.0 1.2 0.2 0.5 0.6 0.2 0.0 0.1 0.1 0.8 0.7 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 1.1 0.0 0.0 1.3 1.2 1.5 2.0 1.0 0.9 1.4 1.4 1.0 0.7 1.3 1.5 0.6 0.0 0.0 0.0 0.2 5.0 7.0 2.8 20.5 0.0 4.6 2.9 0.4 8.6 2.5 1.8 0.0 17.6 0.4 117.9 0.0 12.1 1.4 2.9 1.1 0.8 8.4 0.0 0.2 1.8 56.2 1.5 16.3 4.2 0.0 0.5 0.4 2.3 2.7 0.0 0.2 19.3 0.0 0.0 0.7 2.0 2.5 0.3 0.0 0.0 0.2 0.8 2.1 0.0 0.1 2.2 67.5 0.7 0.2 8.4 62.6 0.8 3.0 0.1 0.0 4.7 3.1 0.2 0.5 14.2 7.0 23.9 0.3 0.0 27.9 21.6 PLEKHH2 "KIAA2028, PLEKHH1L" ENSG00000152527 "Pleckstrin homology, MyTH4 and FERM domain containing H2" Q8IVE3 2 43637260-43767987 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 66.2;Endometrial stromal cells: 150.5;Oligodendrocyte precursor cells: 191.0" "Cancer enhanced" "Detected in many" "renal cancer: 6.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 7.4;RPTEC TERT1: 6.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077225 Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA077225: AB_2686828" "unprognostic (1.11e-1)" "unprognostic (1.05e-1)" "unprognostic (3.49e-2)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (4.27e-3)" "unprognostic (1.77e-1)" "unprognostic (2.32e-2)" "unprognostic (2.94e-2)" "unprognostic (6.99e-2)" "unprognostic (2.81e-1)" "unprognostic (2.53e-2)" "unprognostic (1.92e-3)" "unprognostic (3.03e-2)" "unprognostic (1.29e-1)" "unprognostic (8.57e-3)" "unprognostic (1.82e-2)" 13.1 3.0 2.8 1.7 2.7 0.1 8.9 3.6 2.8 20.9 8.8 11.8 3.7 19.8 4.4 4.6 15.9 7.3 4.8 2.3 2.8 15.9 1.7 27.6 2.9 3.0 3.4 23.0 2.9 5.4 2.0 3.8 3.1 5.1 4.3 1.7 4.8 5.0 1.8 8.4 6.5 9.8 2.7 5.4 5.0 3.9 2.7 0.4 5.5 2.5 1.8 6.2 8.5 2.5 0.5 4.0 1.6 0.0 3.1 7.4 0.3 0.5 2.0 0.8 2.0 0.0 1.3 1.0 0.2 0.6 3.3 2.6 0.5 0.6 1.5 0.0 1.1 0.1 0.6 0.1 0.5 0.0 0.5 2.2 0.6 1.9 0.1 1.1 1.7 1.6 3.9 0.1 0.7 1.1 0.8 0.1 0.9 0.6 3.9 0.0 4.6 0.0 6.3 0.2 1.2 0.6 0.4 0.0 3.9 1.1 0.5 0.1 0.2 4.5 1.3 0.2 1.4 0.9 0.2 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.8 2.7 3.6 2.8 2.3 2.8 3.0 3.4 3.1 2.7 2.7 2.5 4.6 38.5 8.7 19.2 0.9 8.7 17.5 5.8 6.8 1.0 5.3 8.3 2.9 11.5 12.9 66.2 6.2 0.3 1.3 0.1 5.9 6.2 1.6 5.9 150.5 3.8 0.0 0.0 15.6 1.4 0.3 57.4 3.1 8.8 1.3 42.6 2.2 0.0 0.8 0.0 4.3 0.3 2.0 0.3 8.6 3.3 35.8 1.2 12.4 15.9 0.2 5.8 0.0 191.0 52.7 7.2 0.0 50.4 0.4 9.2 0.3 4.1 7.3 4.1 46.0 40.7 24.6 10.8 5.9 2.6 8.4 0.5 3.6 13.1 0.6 8.7 PLEKHO2 "DKFZp761K2312, PLEKHQ1, PP1628, pp9099" ENSG00000241839 "Pleckstrin homology domain containing O2" Q8TD55 15 64841883-64868002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 103.2" "Cell type enhanced" "Detected in many" "Hofbauer cells: 63.2;Kupffer cells: 52.3;Macrophages: 46.5;Muller glia cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "dendritic cells: 27.1;granulocytes: 77.3;monocytes: 73.0" "Cell line enhanced" "Detected in many" "ASC diff: 68.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040055 Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 200000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA040055: AB_10793954" "unprognostic (4.32e-2)" "unprognostic (7.32e-3)" "unprognostic (8.60e-2)" "unprognostic (9.10e-2)" "unprognostic (1.11e-1)" "unprognostic (2.90e-2)" "unprognostic (3.05e-2)" "unprognostic (2.80e-1)" "unprognostic (7.70e-2)" "unprognostic (2.05e-2)" "unprognostic (8.67e-2)" "unprognostic (1.02e-1)" "unprognostic (3.08e-3)" "unprognostic (1.12e-1)" "unprognostic (4.20e-2)" "unprognostic (1.78e-1)" "unprognostic (5.85e-3)" 37.9 31.8 23.1 30.5 26.9 52.0 22.7 25.0 25.0 17.0 16.7 23.6 10.0 19.8 5.7 13.9 22.4 26.0 16.5 21.7 24.4 14.2 11.8 42.2 34.3 31.8 26.2 14.9 8.2 7.4 10.3 25.4 26.6 17.4 7.8 14.4 9.9 13.9 5.8 10.6 17.8 22.9 27.6 103.2 16.3 8.3 28.0 16.0 29.9 8.2 21.1 25.8 16.7 25.5 6.5 4.2 7.9 7.8 68.0 38.8 18.4 18.5 27.4 19.2 19.6 5.1 4.0 17.1 9.5 37.7 19.5 2.2 9.0 7.4 11.2 26.6 2.7 17.2 1.9 6.0 52.2 19.4 24.7 28.3 6.5 24.0 7.8 16.6 27.0 3.5 5.2 59.5 25.9 1.9 4.1 20.9 15.0 3.2 3.7 14.9 19.0 12.2 3.1 4.4 0.6 6.7 7.7 2.6 25.4 12.9 2.7 26.1 35.3 14.8 13.4 14.1 7.8 22.0 37.1 5.8 16.0 24.8 8.8 22.2 43.2 25.6 13.2 52.3 11.9 9.8 7.4 12.2 27.1 6.8 3.1 6.5 77.3 7.0 73.0 3.1 10.7 36.0 23.1 26.9 25.0 25.0 21.7 24.4 31.8 26.2 26.6 27.6 28.0 25.5 24.9 0.0 5.6 17.3 9.1 5.6 2.3 2.3 0.6 0.6 6.4 8.3 3.6 2.8 2.4 9.2 0.0 4.2 15.9 0.5 3.9 2.4 5.0 1.4 5.9 26.1 0.0 2.1 0.2 1.5 5.9 8.6 0.5 2.3 18.4 2.5 34.2 2.1 63.2 0.0 0.2 0.3 4.1 52.3 24.3 2.9 18.3 46.5 14.2 8.4 18.9 56.8 16.5 2.5 2.7 2.0 0.0 25.6 2.7 3.5 0.0 2.2 2.1 3.8 13.1 10.2 5.9 0.9 2.3 1.9 4.4 6.0 10.5 4.6 0.4 3.4 PLIN4 "KIAA1881, S3-12" ENSG00000167676 "Perilipin 4" Q96Q06 19 4502180-4518465 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 764.9;breast: 316.5;skeletal muscle: 249.9" "Cell type enhanced" "Detected in some" "Adipocytes: 12.3;Astrocytes: 12.1;Cardiomyocytes: 35.9;Hepatocytes: 30.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "ASC diff: 249.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA044682, HPA054657" Enhanced Enhanced "Lipid droplets,Plasma membrane,Cytosol" NA NA 55000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Lipid droplets" "HPA044682: AB_2679044, HPA054657: AB_2682559" "unprognostic (2.97e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (8.31e-4)" "prognostic unfavorable (2.31e-4)" "unprognostic (6.65e-2)" "unprognostic (6.77e-2)" "unprognostic (1.03e-1)" "unprognostic (5.23e-2)" "unprognostic (9.89e-3)" "unprognostic (1.05e-1)" "unprognostic (2.95e-2)" "unprognostic (1.81e-1)" "unprognostic (1.90e-1)" "unprognostic (6.09e-3)" "unprognostic (3.10e-2)" "unprognostic (2.13e-1)" "unprognostic (4.94e-3)" 764.9 3.9 8.5 6.4 9.4 2.7 316.5 8.0 5.1 8.8 2.5 70.7 2.3 28.7 2.0 9.6 18.5 8.5 112.8 5.0 6.7 7.6 87.1 3.4 0.8 9.8 9.7 21.8 24.7 0.1 4.4 0.1 7.3 13.4 3.9 0.2 22.6 15.1 249.9 16.3 18.9 20.4 8.5 4.9 25.1 2.7 11.1 0.9 4.1 163.4 0.2 34.3 7.2 7.1 0.1 0.4 0.1 0.7 249.6 1.6 8.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.4 0.0 1.2 0.1 0.0 1.8 0.0 0.6 0.3 0.0 0.1 1.4 3.6 0.1 0.1 8.1 4.7 0.0 0.4 0.1 0.0 0.0 0.2 0.5 0.0 0.5 0.0 0.2 0.3 0.1 5.7 0.3 0.0 0.2 0.0 29.7 0.1 0.4 0.3 0.0 0.0 0.1 1.3 0.1 0.2 0.1 0.1 0.2 0.1 0.4 0.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.5 9.4 8.0 5.1 5.0 6.7 9.8 9.7 7.3 8.5 11.1 7.1 12.3 0.0 7.2 12.1 0.2 0.3 1.2 0.4 0.6 0.3 0.9 3.9 35.9 7.2 2.1 0.0 0.0 0.1 0.3 0.0 0.0 0.7 0.3 1.6 0.4 1.0 0.0 0.0 0.3 1.5 0.3 1.7 3.6 0.6 0.0 1.0 7.5 30.6 0.1 0.0 0.2 0.0 0.0 1.2 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.6 0.0 0.5 0.0 0.6 0.0 4.1 0.0 0.4 0.0 0.9 0.9 0.0 6.6 5.9 1.8 0.5 0.4 0.3 0.3 0.4 0.1 0.3 0.3 1.9 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLPPR5 "LPPR5, PAP2, PAP2D, PRG5" ENSG00000117598 "Phospholipid phosphatase related 5" Q32ZL2 1 98890245-99005032 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.1;retina: 1.6;testis: 2.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 8.5;Horizontal cells: 3.3;Spermatogonia: 6.9" "Group enriched" "Detected in some" 13 "glioma: 2.7;renal cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "PC-3: 11.9;SH-SY5Y: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018072, HPA059085" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Cytosol "HPA018072: AB_1854958, HPA059085: AB_2732631" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.22e-4)" "unprognostic (1.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" 0.0 0.4 5.2 0.0 5.8 0.0 0.0 0.1 6.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 4.5 0.0 0.0 0.0 0.0 1.3 3.9 0.0 0.4 0.0 0.2 0.0 2.8 0.0 0.1 1.6 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.0 7.1 0.0 0.0 0.0 0.0 0.2 0.0 3.5 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.9 0.0 0.0 0.0 0.5 0.1 0.4 21.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.8 0.1 6.6 6.1 4.5 1.3 3.9 2.8 2.0 7.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.1 0.1 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 PLSCR1 MMTRA1B ENSG00000188313 "Phospholipid scramblase 1" O15162 3 146515180-146544856 "Predicted intracellular proteins, Transporters" "Antiviral defense, Host-virus interaction" "DNA-binding, Host cell receptor for virus entry, Hydrolase, Nuclease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 319.8;BJ hTERT+ SV40 Large T+ RasG12V: 418.6;HHSteC: 292.9;SK-MEL-30: 569.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068923, CAB070421" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Plasma membrane" "Golgi apparatus" "CAB070421: AB_11153452, HPA068923: AB_2686059" "unprognostic (7.88e-2)" "unprognostic (1.10e-1)" "unprognostic (5.34e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.12e-1)" "unprognostic (3.35e-1)" "unprognostic (5.22e-2)" "unprognostic (7.73e-3)" "unprognostic (9.19e-3)" "unprognostic (6.93e-3)" "unprognostic (3.07e-3)" "unprognostic (1.10e-1)" "unprognostic (1.09e-3)" "unprognostic (5.26e-2)" "unprognostic (1.64e-2)" "unprognostic (1.76e-1)" "unprognostic (1.63e-1)" 60.6 23.0 11.4 86.7 12.5 64.4 45.9 12.7 17.6 25.9 11.9 65.0 39.8 28.2 31.0 47.9 40.0 66.1 24.3 12.1 13.5 71.9 49.2 49.3 40.6 17.4 14.2 34.9 38.3 16.8 15.4 56.3 15.3 23.7 59.5 9.8 49.1 49.6 10.8 13.6 45.4 41.9 16.2 64.5 44.0 17.1 14.7 30.0 27.8 17.6 39.4 68.1 29.5 14.0 106.2 41.5 26.4 12.1 40.9 65.0 40.5 32.6 88.4 319.8 418.6 34.0 88.1 8.4 75.6 20.6 245.9 86.2 21.2 32.7 56.6 32.9 21.6 66.1 12.5 25.2 292.9 40.3 35.4 106.3 53.3 36.6 182.3 52.6 49.4 19.1 44.7 104.0 66.9 41.0 30.6 16.1 25.8 71.6 37.6 27.4 28.1 2.9 95.9 29.6 16.3 0.0 42.6 20.9 569.9 35.8 20.7 46.8 30.6 26.9 22.7 59.1 55.8 79.2 15.6 0.4 27.0 29.0 23.3 41.1 157.6 44.3 20.8 159.6 30.0 25.2 13.5 18.5 105.8 19.7 9.3 13.9 100.0 57.8 94.8 28.5 8.3 79.3 11.4 12.5 12.7 17.6 12.1 13.5 17.4 14.2 15.3 16.2 14.7 14.0 191.4 35.3 43.0 12.7 28.2 37.0 106.5 92.1 26.2 0.7 36.0 22.6 7.3 124.4 110.4 95.6 0.0 53.7 25.4 134.2 74.3 291.6 2.0 56.1 24.5 135.2 33.1 18.3 7.1 217.4 114.1 74.8 47.9 58.2 28.4 60.5 100.6 29.7 139.9 0.0 9.0 71.5 79.3 86.2 162.9 6.8 114.9 185.5 48.0 35.6 72.3 64.3 32.0 7.1 0.3 157.6 110.3 45.9 18.2 79.6 40.7 75.0 133.5 1.6 39.5 63.4 59.2 1.5 2.4 21.8 28.6 44.5 25.9 42.6 69.4 211.9 PLVAP "FELS, gp68, PV-1, PV1" ENSG00000130300 "Plasmalemma vesicle associated protein" Q9BX97 19 17351450-17377342 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 436.2" "Group enriched" "Detected in many" 4 "Adipocytes: 439.2;Endothelial cells: 344.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "plasmacytoid DC: 35.2" "Lineage enriched" "Detected in many" 6 "dendritic cells: 35.2" "Cell line enriched" "Detected in some" 27 "EFO-21: 549.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002279 Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA 53000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane, Centrosome" "HPA002279: AB_1079636" "unprognostic (3.19e-1)" "unprognostic (8.22e-2)" "unprognostic (7.87e-2)" "unprognostic (2.38e-2)" "unprognostic (1.93e-2)" "unprognostic (2.49e-3)" "unprognostic (4.17e-3)" "unprognostic (1.01e-1)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.53e-2)" "unprognostic (8.96e-2)" "unprognostic (4.24e-3)" "unprognostic (4.70e-3)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (8.17e-2)" 283.0 51.1 2.7 54.6 3.1 1.7 210.5 2.9 4.2 102.7 18.2 95.7 86.7 90.0 5.1 48.9 83.3 139.2 92.5 3.3 3.1 153.0 6.9 31.0 50.5 3.7 3.5 16.7 96.1 98.6 64.3 48.8 3.6 68.4 22.3 0.0 77.9 38.0 32.7 58.9 103.3 50.5 3.6 166.7 116.6 4.4 3.5 18.9 436.2 12.9 16.2 104.4 80.8 4.1 0.3 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 549.1 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 9.5 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.7 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.1 20.0 0.0 2.3 0.1 0.3 0.5 2.2 2.5 0.0 0.2 0.0 0.0 0.2 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2.7 35.2 0.0 0.6 2.7 3.1 2.9 4.2 3.3 3.1 3.7 3.5 3.6 3.6 3.5 4.1 439.2 6.4 0.0 0.3 0.7 22.9 1.0 0.0 8.0 0.0 2.7 3.3 3.7 0.0 0.0 0.0 0.0 0.1 5.1 0.0 0.0 1.7 3.6 0.4 0.3 344.9 0.0 0.4 0.4 2.5 0.1 48.9 0.0 0.3 0.0 0.4 79.6 0.2 1.8 0.0 0.3 0.0 0.0 3.5 28.8 0.8 0.0 5.5 23.2 6.5 0.0 0.5 0.0 0.0 0.3 0.1 0.0 0.0 7.6 1.5 0.0 0.0 0.0 0.1 0.0 1.4 6.1 0.5 0.7 2.9 16.8 0.1 1.4 0.7 0.0 2.3 PLXNA3 "6.3, Plxn3, PLXN4, SEX, XAP-6" ENSG00000130827 "Plexin A3" P51805 X 154458281-154477779 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058989 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 94000 "Cluster 11: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" Nucleoplasm "HPA058989: AB_2683872" "unprognostic (2.79e-2)" "unprognostic (3.03e-1)" "unprognostic (1.04e-3)" "unprognostic (8.04e-3)" "unprognostic (1.63e-1)" "unprognostic (9.05e-3)" "unprognostic (1.06e-2)" "unprognostic (2.25e-1)" "unprognostic (2.42e-1)" "unprognostic (6.26e-2)" "unprognostic (1.05e-1)" "unprognostic (4.10e-2)" "unprognostic (1.38e-3)" "unprognostic (2.30e-1)" "unprognostic (3.00e-1)" "unprognostic (4.33e-2)" "unprognostic (5.73e-2)" 6.5 7.0 5.7 3.5 6.4 1.7 6.0 7.5 7.2 10.7 5.3 7.5 3.6 8.1 4.3 5.3 8.7 3.9 7.1 5.5 8.6 5.8 2.8 8.4 3.8 6.4 7.3 17.0 7.6 2.0 24.8 3.6 7.2 10.5 2.2 1.5 12.0 3.4 1.7 10.1 7.8 2.6 4.6 8.0 5.5 3.7 9.0 2.2 10.2 1.1 2.6 7.4 9.7 8.6 11.2 2.2 6.3 16.1 6.5 8.3 8.4 15.6 3.3 3.6 4.9 8.2 4.6 2.0 8.2 16.9 8.4 9.6 6.4 7.6 1.3 0.9 4.8 2.0 29.0 4.5 5.2 1.0 8.8 11.3 5.5 5.4 0.4 12.4 4.1 3.2 5.2 1.6 5.7 13.8 1.9 8.4 2.0 3.4 4.9 7.2 0.5 0.7 4.8 7.2 13.2 6.8 5.7 10.3 2.6 4.4 6.2 2.4 10.4 7.8 7.0 0.8 6.7 1.2 0.2 2.9 14.5 1.5 2.1 0.7 0.0 0.1 0.1 0.0 0.1 0.3 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.3 0.0 0.0 0.1 0.0 5.7 6.4 7.5 7.2 5.5 8.6 6.4 7.3 7.2 4.6 9.0 8.6 5.2 12.8 7.7 13.4 9.8 8.7 9.0 7.3 9.6 18.7 13.9 10.3 6.5 2.8 6.8 11.0 12.5 3.0 10.3 15.9 0.0 11.5 0.1 14.4 23.2 3.9 7.2 0.0 6.5 5.8 7.2 11.0 17.9 30.4 8.8 21.3 2.9 1.6 8.5 5.0 5.4 15.1 0.0 3.5 9.2 0.8 11.5 10.5 14.2 6.5 4.7 6.5 4.1 6.0 4.1 13.6 11.4 8.6 8.5 10.3 9.4 1.5 10.9 7.8 13.1 26.5 9.4 0.9 2.3 8.1 7.4 9.3 13.2 2.5 9.6 8.2 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PNCK "CaMK1b, MGC45419" ENSG00000130822 "Pregnancy up-regulated nonubiquitous CaM kinase" Q6P2M8 X 153669733-153689010 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 65.1;intestine: 81.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 40.9;Excitatory neurons: 29.0;Extravillous trophoblasts: 63.9;Granulosa cells: 46.9;Syncytiotrophoblasts: 49.5" "Cancer enhanced" "Detected in many" "renal cancer: 15.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 9 "AN3-CA: 33.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007458 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA007458: AB_1079644" "unprognostic (1.56e-1)" "unprognostic (2.56e-1)" "unprognostic (1.16e-2)" "unprognostic (5.95e-3)" "unprognostic (1.83e-2)" "unprognostic (3.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.72e-1)" "unprognostic (1.08e-1)" "unprognostic (1.46e-2)" "unprognostic (3.60e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (1.04e-6)" "unprognostic (2.86e-3)" "unprognostic (1.43e-1)" "unprognostic (2.66e-1)" "unprognostic (6.26e-3)" 1.6 1.2 43.7 1.9 48.8 0.0 0.6 6.5 53.3 1.3 4.8 81.7 3.4 6.5 1.7 14.0 4.1 2.6 6.5 49.8 40.8 1.9 0.2 0.6 0.0 19.6 22.8 0.9 0.3 0.5 1.8 2.0 21.1 17.2 3.8 7.9 0.4 37.6 2.0 1.8 13.4 15.7 15.0 0.2 15.9 8.8 65.1 1.4 0.3 0.3 0.1 27.4 2.2 28.5 0.3 0.1 0.4 33.9 0.0 0.0 3.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 1.0 0.0 0.2 0.4 0.5 0.0 0.0 0.0 3.9 0.0 0.0 0.5 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.6 0.0 0.3 0.4 0.3 0.2 0.7 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.2 3.7 0.0 0.1 2.7 0.9 0.3 0.4 0.0 0.2 1.2 0.0 0.2 0.2 0.0 0.2 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.7 48.8 6.5 53.3 49.8 40.8 19.6 22.8 21.1 15.0 65.1 28.5 0.0 0.0 0.0 18.9 0.0 0.6 0.4 40.9 0.0 21.6 0.3 0.9 3.0 0.0 18.0 0.0 22.9 13.5 0.1 1.7 0.0 0.4 0.3 0.3 4.4 0.3 0.0 0.0 29.0 0.4 63.9 0.5 0.0 0.3 0.0 46.9 0.0 0.0 2.4 0.0 24.2 1.1 12.2 0.0 0.0 0.8 0.0 0.3 1.8 1.0 0.0 3.2 0.0 11.1 13.2 2.9 0.1 0.4 0.0 0.3 20.3 0.4 2.6 19.4 0.0 0.0 4.0 0.6 0.9 0.0 0.6 49.5 0.1 0.6 0.4 1.0 PNISR "bA98I9.2, C6orf111, DKFZp564B0769, FLJ14752, SFRS18, SRrp130" ENSG00000132424 "PNN interacting serine and arginine rich protein" Q8TF01 6 99397629-99425331 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038796, HPA075076" Approved Supported "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 51: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane, Cytosol" "HPA038796: AB_10672652, HPA075076: " "unprognostic (2.95e-1)" "unprognostic (2.29e-1)" "unprognostic (2.11e-1)" "unprognostic (9.72e-3)" "unprognostic (1.68e-2)" "unprognostic (8.55e-3)" "unprognostic (4.41e-2)" "unprognostic (1.58e-3)" "unprognostic (5.82e-2)" "unprognostic (4.32e-3)" "prognostic favorable (5.27e-4)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.41e-4)" "unprognostic (3.43e-2)" "unprognostic (2.59e-1)" "unprognostic (8.89e-2)" "prognostic favorable (1.09e-4)" 68.2 68.8 56.9 52.0 55.4 106.8 75.3 78.4 89.8 103.1 67.5 114.5 51.4 79.7 93.6 51.8 93.2 38.2 84.6 54.3 56.4 67.1 62.2 74.4 78.7 56.7 54.7 123.0 66.0 38.4 112.0 36.4 52.9 91.2 49.4 102.1 76.6 48.1 89.4 64.1 94.1 49.4 49.3 90.6 77.1 39.4 56.9 51.4 114.5 31.2 54.9 81.6 80.3 60.1 26.7 19.5 98.8 72.0 35.3 46.8 45.8 44.1 22.8 25.6 29.9 33.3 49.2 85.8 26.6 25.3 28.7 41.9 49.3 33.3 45.2 75.0 48.8 52.6 105.0 30.6 22.2 73.0 67.9 51.8 50.0 27.4 37.5 95.7 34.2 44.8 59.3 52.5 31.3 25.2 31.8 71.2 55.2 24.5 15.3 62.1 29.6 32.4 47.1 47.1 43.4 51.9 21.7 23.6 35.3 75.4 32.8 58.6 45.0 25.2 28.9 25.7 37.2 35.9 24.3 70.5 37.5 68.3 27.0 12.3 10.8 11.9 12.5 6.4 13.0 19.3 12.0 10.4 5.0 25.8 17.9 16.6 30.0 23.5 7.7 19.6 12.4 3.7 56.9 55.4 78.4 89.8 54.3 56.4 56.7 54.7 52.9 49.3 56.9 60.1 175.8 185.9 237.6 356.2 375.8 195.3 357.3 250.5 165.6 546.2 143.9 192.5 121.2 137.2 215.7 178.4 446.2 158.3 336.4 152.4 74.3 130.8 17.0 132.2 185.7 210.7 247.8 194.4 241.5 104.5 102.1 240.1 100.9 140.5 190.5 344.5 135.7 109.4 99.7 498.0 257.4 129.6 199.4 128.0 236.8 47.9 593.3 152.1 167.2 193.9 261.6 223.6 375.9 270.4 252.6 133.1 176.2 441.2 209.8 293.6 205.8 58.6 179.6 419.9 249.8 288.7 236.3 342.6 181.3 115.5 173.6 180.9 283.8 363.3 151.3 352.4 PODXL "Gp200, PC, PCLP" ENSG00000128567 "Podocalyxin like" O00592 7 131500262-131558217 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 96.2" "Cell type enhanced" "Detected in many" "Adipocytes: 165.8;Cone photoreceptor cells: 87.6;Endothelial cells: 181.1;Glandular and luminal cells: 121.3;Microglial cells: 92.8;Rod photoreceptor cells: 188.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 295.8;NTERA-2: 509.7;SuSa: 640.8;TIME: 474.0;U-251 MG: 226.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002110, CAB016169, HPA045507, CAB062558, CAB068219, CAB068220" Enhanced Supported "Vesicles,Plasma membrane,Centriolar satellite" NA NA 33000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Centriolar satellite" Vesicles "CAB016169: AB_628165, CAB062558: AB_2665627, CAB068219: AB_2665618, CAB068220: AB_2665619, HPA002110: AB_1855512, HPA045507: AB_2679356" "unprognostic (1.26e-1)" "unprognostic (7.68e-2)" "unprognostic (8.28e-3)" "unprognostic (6.46e-3)" "unprognostic (5.16e-3)" "unprognostic (5.85e-2)" "unprognostic (1.63e-2)" "unprognostic (1.05e-1)" "unprognostic (7.95e-3)" "unprognostic (3.52e-1)" "unprognostic (9.20e-3)" "unprognostic (3.40e-1)" "prognostic favorable (2.89e-4)" "unprognostic (2.56e-1)" "unprognostic (8.78e-3)" "unprognostic (3.55e-2)" "unprognostic (1.03e-1)" 20.8 6.8 27.7 8.9 26.5 0.3 21.9 25.2 34.4 26.0 19.0 8.4 5.1 27.5 5.6 8.1 49.0 14.5 29.1 25.2 25.3 96.2 3.0 31.8 5.6 29.2 28.1 6.1 26.0 18.9 1.1 29.3 29.5 8.7 8.6 67.8 16.1 18.9 15.3 4.8 6.2 28.9 22.0 5.6 5.6 2.4 42.0 3.7 28.5 26.1 6.1 9.6 1.0 22.0 50.9 18.9 42.6 16.3 0.5 0.0 2.6 5.4 4.2 16.9 6.1 121.4 83.1 0.3 109.7 295.8 57.1 34.9 34.3 0.7 15.3 5.4 17.3 0.2 115.0 2.7 1.1 4.2 4.0 0.2 0.4 50.5 0.8 9.4 146.3 1.5 10.5 1.8 16.9 18.0 0.5 1.3 509.7 10.0 43.6 16.2 73.1 15.8 1.6 16.6 34.3 8.9 34.7 7.0 0.2 640.8 4.1 2.2 474.0 6.8 26.6 72.5 226.1 2.5 4.5 1.2 27.1 20.1 48.4 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.7 26.5 25.2 34.4 25.2 25.3 29.2 28.1 29.5 22.0 42.0 22.0 165.8 6.4 9.9 3.6 2.4 5.2 0.9 14.0 0.6 9.7 33.3 20.7 22.9 4.3 25.4 27.6 87.6 0.8 1.0 1.0 0.0 4.6 0.8 44.8 13.0 181.1 2.4 2.7 9.4 18.3 0.4 9.2 1.1 121.3 2.5 2.2 65.0 1.0 0.4 5.0 3.3 12.9 4.1 0.9 9.6 1.3 4.7 2.6 5.4 92.8 0.7 10.6 0.0 7.1 3.1 42.7 0.8 0.4 4.3 3.6 0.7 0.8 10.3 188.4 0.0 6.3 8.4 0.3 1.1 1.3 3.1 0.7 3.3 1.9 2.7 5.8 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 POU2F3 "Epoc-1, OCT11, PLA-1, Skn-1a" ENSG00000137709 "POU class 2 homeobox 3" Q9UKI9 11 120236640-120319945 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skin 1: 48.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 20.9;Pancreatic endocrine cells: 20.8;Suprabasal keratinocytes: 37.6;Urothelial cells: 14.2" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;CAPAN-2: 3.6;EFO-21: 1.3;SK-BR-3: 2.5;T-47d: 3.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA019652, HPA073468" Enhanced Approved "Nucleoplasm,Nucleoli,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 61: Skin - Cornification" "Cluster 6: T47d - Mammary gland" "Cluster 16: Pancreatic endocrine cells - Mixed function" Nucleoplasm "Nucleoli, Nuclear bodies, Plasma membrane, Cytosol" "HPA019652: AB_1855585, HPA073468: " "unprognostic (1.75e-1)" "unprognostic (2.12e-2)" "unprognostic (6.37e-2)" "unprognostic (2.41e-4)" "unprognostic (2.60e-1)" "unprognostic (4.46e-3)" "unprognostic (8.56e-3)" "unprognostic (9.34e-2)" "unprognostic (3.45e-2)" "unprognostic (1.12e-1)" "unprognostic (1.40e-3)" "unprognostic (2.08e-1)" "unprognostic (1.27e-2)" "unprognostic (9.69e-3)" "unprognostic (1.70e-1)" "prognostic favorable (8.14e-4)" "unprognostic (1.45e-1)" 0.1 0.1 0.2 0.1 0.1 0.2 2.0 0.3 0.4 0.8 0.0 0.6 0.9 0.0 1.7 1.3 0.5 0.7 0.1 0.1 0.1 0.3 0.1 1.0 0.2 0.1 0.1 0.1 0.2 6.3 0.4 0.3 0.1 0.6 0.2 0.1 1.1 2.0 0.2 48.0 0.7 0.3 0.0 0.2 0.7 0.1 0.1 0.2 0.7 0.0 0.5 0.4 2.1 0.3 1.4 0.0 0.0 0.1 0.0 0.0 0.4 0.2 0.3 0.0 0.0 0.0 3.6 0.1 1.3 0.0 0.0 0.6 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 2.5 0.0 0.3 3.9 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.4 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.3 0.2 0.0 8.2 0.3 0.0 20.9 10.6 5.0 1.8 0.0 3.0 1.5 0.8 0.0 3.9 11.0 0.0 1.5 0.1 0.9 0.0 5.3 2.2 1.3 0.7 0.3 3.0 0.0 0.4 1.3 0.4 0.6 10.2 4.8 0.0 0.0 0.0 0.3 0.1 0.0 0.5 0.2 8.2 0.0 2.2 5.5 0.0 0.1 5.4 0.0 0.0 0.4 0.0 0.0 0.5 20.8 1.1 0.0 0.0 5.0 0.4 0.1 1.8 0.0 0.0 0.0 0.4 0.0 0.1 7.0 37.6 7.9 0.5 0.2 0.6 14.2 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;testis: 14.6" "Group enriched" "Detected in some" 9 "Early spermatids: 64.0;Late spermatids: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;HeLa: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.2 1.3 0.0 2.0 1.0 2.3 1.8 2.6 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 1.6 1.4 0.2 0.1 0.3 0.1 3.5 2.1 0.2 0.1 0.0 0.5 0.6 2.4 0.4 0.0 1.4 0.1 0.3 0.1 0.4 0.1 0.0 1.8 0.2 0.1 14.6 1.5 0.1 0.2 0.0 0.1 0.2 0.1 5.8 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.0 1.8 2.6 1.6 1.4 3.5 2.1 2.4 1.8 1.5 5.8 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 4.7 0.0 0.0 0.0 0.3 139.0 0.6 0.0 3.6 1.0 0.1 0.6 0.0 0.5 2.2 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 1.2 1.2 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 201.3;Endothelial cells: 189.5;Excitatory neurons: 206.1;Oligodendrocytes: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001924: AB_1079665, HPA071162: " "unprognostic (5.27e-2)" "unprognostic (5.71e-2)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.94e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.11e-4)" "unprognostic (7.33e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.92e-2)" "prognostic favorable (5.11e-7)" "unprognostic (8.54e-2)" "unprognostic (7.54e-2)" "unprognostic (2.64e-1)" "unprognostic (4.09e-2)" 32.4 27.0 22.5 13.7 33.6 3.3 37.9 0.3 29.5 24.0 18.3 25.0 11.9 27.7 11.4 28.6 26.6 20.1 77.0 29.0 10.0 36.3 26.7 39.6 9.3 7.0 14.9 85.2 21.3 17.1 19.6 60.2 11.2 24.7 18.2 5.1 21.6 29.3 25.9 30.4 15.0 31.3 5.9 29.9 25.5 11.9 31.6 18.5 39.0 44.3 10.5 24.4 29.5 22.9 18.8 37.1 29.7 25.5 48.4 133.3 52.9 67.0 75.2 38.6 55.4 98.0 55.9 14.2 75.6 135.7 51.5 46.0 16.3 61.0 69.1 32.3 9.0 31.3 28.3 14.6 21.0 9.8 16.9 104.8 41.3 112.1 114.0 75.2 134.0 18.9 16.7 13.9 138.5 14.4 9.1 2.8 53.4 26.8 28.5 14.6 74.0 5.5 56.6 41.0 2.4 12.1 33.4 17.6 91.3 206.5 22.7 14.3 131.3 107.7 36.0 59.8 68.8 0.2 0.4 1.2 119.7 13.7 173.7 0.9 0.2 0.1 0.3 0.0 0.6 0.3 0.5 0.3 0.3 2.7 0.5 0.5 0.6 0.1 0.1 0.9 0.8 0.2 22.5 33.6 0.3 29.5 29.0 10.0 7.0 14.9 11.2 5.9 31.6 22.9 201.3 99.3 19.8 7.5 9.4 41.0 76.5 42.8 68.3 15.5 19.6 40.3 164.0 10.0 18.3 80.9 4.2 37.2 2.5 8.0 11.7 42.2 3.5 40.2 12.7 189.5 18.6 8.6 206.1 24.8 23.2 74.6 46.9 73.3 3.8 132.8 157.8 14.0 8.9 45.4 68.4 15.9 10.2 16.7 30.9 5.4 21.1 6.2 62.2 174.3 3.1 6.3 0.0 116.6 202.9 33.9 19.7 42.2 4.6 45.0 8.6 48.7 9.0 1.8 19.7 71.7 78.9 2.4 8.6 48.2 27.6 91.9 5.9 25.4 12.5 84.5 PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590253 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 41.7;Excitatory neurons: 46.6;Inhibitory neurons: 37.6;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 45.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA039380: AB_10673528" "unprognostic (8.72e-2)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.78e-1)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (2.59e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (6.67e-2)" "unprognostic (2.85e-3)" "prognostic favorable (7.14e-8)" "unprognostic (2.67e-2)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (7.95e-3)" 6.6 14.8 5.7 7.3 9.8 5.9 10.3 45.4 21.0 8.3 1.1 17.6 24.7 7.4 15.1 11.6 9.4 8.3 7.5 8.0 1.8 8.5 5.6 5.8 7.8 6.0 0.6 9.2 9.4 33.7 21.6 4.5 8.8 10.0 17.6 53.7 13.8 8.3 20.0 20.0 24.3 7.7 0.0 8.6 15.5 15.5 2.8 5.4 14.3 21.2 10.0 9.0 9.9 9.2 14.5 9.3 8.1 15.0 4.8 3.0 13.8 7.1 9.0 10.0 14.6 11.0 13.5 13.5 10.5 9.8 14.9 38.6 15.8 30.6 10.1 13.3 12.5 20.3 29.9 5.9 11.0 23.4 20.2 5.4 26.6 12.2 18.6 13.5 10.7 31.0 15.0 19.4 7.4 11.3 7.8 13.2 3.9 27.0 10.0 16.7 8.2 6.8 10.7 25.9 24.1 7.6 18.3 17.2 6.7 11.4 31.7 19.4 4.7 8.7 10.2 11.1 17.4 4.3 5.7 16.4 16.3 26.5 8.5 2.4 0.5 0.0 1.0 1.1 1.3 2.0 1.2 1.3 1.2 1.2 0.9 0.9 0.3 1.5 0.8 0.9 0.3 1.3 5.7 9.8 45.4 21.0 8.0 1.8 6.0 0.6 8.8 0.0 2.8 9.2 2.3 0.0 2.2 11.4 5.2 4.0 1.5 3.2 7.4 16.5 3.2 3.3 5.4 2.8 3.4 7.3 41.7 3.3 2.9 9.2 0.0 2.1 2.7 2.1 1.4 2.9 2.4 5.5 46.6 1.5 0.9 1.8 20.9 2.8 0.0 9.5 3.3 1.8 1.9 10.1 37.6 5.9 0.0 2.8 1.8 2.4 1.8 2.1 0.0 15.0 1.8 3.9 0.0 11.6 11.0 1.9 5.2 7.2 3.1 1.2 12.2 1.5 2.3 44.2 6.6 2.3 3.2 8.1 3.3 7.3 3.3 2.2 3.1 3.5 8.2 3.2 PPL ENSG00000118898 Periplakin O60437 16 4882507-4960741 "Plasma proteins, Predicted intracellular proteins" Keratinization "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 728.1;vagina: 288.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 73.7;Squamous epithelial cells: 138.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 86.5;HaCaT: 191.1;MCF7: 71.5;SiHa: 102.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042550, HPA059859" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 80000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA042550: AB_2678048, HPA059859: AB_2684145" "unprognostic (2.12e-2)" "unprognostic (1.78e-1)" "unprognostic (1.16e-1)" "unprognostic (3.90e-2)" "unprognostic (2.84e-2)" "unprognostic (1.40e-1)" "unprognostic (3.70e-3)" "unprognostic (5.58e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (2.76e-4)" "unprognostic (2.41e-2)" "unprognostic (1.31e-1)" "unprognostic (4.13e-3)" "unprognostic (2.43e-2)" "unprognostic (2.25e-1)" "unprognostic (1.19e-1)" "unprognostic (7.86e-2)" 56.3 4.9 2.5 1.0 3.2 0.2 39.8 0.3 4.2 163.0 3.3 10.4 6.5 5.7 7.3 728.1 11.5 7.1 5.7 3.6 0.0 13.2 13.3 18.6 0.4 0.0 2.8 5.9 10.6 4.1 14.3 6.4 1.1 17.3 3.4 2.4 149.5 11.5 12.0 188.4 12.3 1.7 0.0 0.3 11.1 1.9 0.0 3.5 22.1 5.3 57.0 22.0 288.6 0.5 24.0 8.6 0.1 0.1 60.0 86.5 29.6 0.1 1.6 0.2 0.6 39.5 59.5 0.4 13.5 1.2 3.4 191.1 1.3 23.0 0.0 0.0 1.3 0.1 46.3 7.1 3.8 0.1 0.1 4.2 20.7 0.2 7.1 4.6 0.1 0.2 0.2 0.2 0.1 71.5 0.1 0.2 6.0 31.3 18.1 0.1 0.1 30.0 44.6 37.5 30.9 0.3 102.5 33.8 0.3 8.9 17.4 0.5 0.3 0.2 0.3 0.3 0.1 0.4 1.1 0.1 12.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.5 3.2 0.3 4.2 3.6 0.0 0.0 2.8 1.1 0.0 0.0 0.5 4.1 73.7 29.1 1.6 1.2 35.1 32.5 30.5 35.9 8.4 18.8 13.8 5.1 35.8 42.6 57.0 6.2 2.1 2.0 3.6 1.9 18.4 0.7 31.6 4.1 8.0 39.4 0.0 6.6 4.5 1.6 38.0 9.2 28.0 0.0 0.8 2.9 12.7 0.7 1.7 2.5 3.8 18.3 0.9 9.0 1.3 55.3 1.4 17.8 1.0 1.2 3.7 2.1 1.0 1.7 23.4 8.3 4.1 0.2 35.1 13.5 1.2 32.5 12.5 0.0 28.7 4.3 3.9 3.1 138.0 51.3 1.4 2.7 0.4 4.8 53.2 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.9" "Cell type enhanced" "Detected in all" "Early spermatids: 446.2;Late spermatids: 565.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 380000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Plasma membrane" "HPA029209: AB_2672951" "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 22.7 19.2 14.0 22.2 16.5 142.9 23.5 27.0 22.4 22.4 3.3 36.6 36.8 28.0 19.3 25.7 17.3 20.1 36.8 16.7 24.4 42.5 51.2 20.3 24.4 18.2 16.3 16.2 25.5 36.8 14.3 22.1 20.0 29.9 36.0 51.0 31.5 23.0 78.9 21.9 37.3 26.5 15.3 20.4 23.2 54.5 16.4 31.1 24.3 76.6 26.2 21.4 17.8 23.1 129.7 28.6 24.4 20.9 36.5 33.6 31.1 34.8 40.7 25.3 23.8 16.3 37.2 77.1 32.4 39.6 18.7 28.1 25.5 35.9 44.0 70.1 14.4 47.6 19.5 25.7 30.6 54.7 32.6 28.6 42.1 29.7 40.4 29.5 25.1 38.7 26.9 59.6 31.3 56.5 71.5 12.8 23.0 25.8 23.9 25.3 56.5 25.0 30.4 61.2 41.2 31.0 36.1 41.7 30.1 22.2 42.0 23.5 35.1 52.4 52.0 23.3 25.0 46.1 28.1 89.9 24.0 21.2 27.1 5.4 1.0 3.0 1.8 1.0 1.9 0.9 1.4 1.6 1.5 3.0 1.1 1.0 4.4 2.9 1.2 0.9 2.6 0.9 14.0 16.5 27.0 22.4 16.7 24.4 18.2 16.3 20.0 15.3 16.4 23.1 25.9 16.0 22.6 43.8 34.2 77.4 41.3 17.6 34.7 42.2 41.6 22.7 95.0 44.3 20.0 38.6 64.6 31.9 49.1 111.2 33.2 24.6 446.2 31.3 34.6 31.5 60.9 93.5 77.8 24.4 24.0 36.6 25.5 38.8 26.6 20.7 22.9 73.3 28.2 58.9 71.6 60.2 22.4 33.5 51.0 565.6 42.3 58.6 60.5 25.3 26.8 40.1 45.3 66.4 53.4 34.6 87.8 52.3 45.4 86.5 128.5 90.0 17.8 66.8 39.5 36.2 35.9 69.8 25.3 32.9 82.3 73.5 40.8 19.4 42.1 69.6 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 42.2;Hepatic stellate cells: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.6" "Group enriched" "Detected in all" 7 "dendritic cells: 8.9;granulocytes: 28.6;monocytes: 24.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 109.1;K-562: 173.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 510000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 24.1 18.1 14.9 21.6 13.9 26.8 17.6 11.6 15.7 18.5 11.8 17.1 8.9 19.9 3.8 22.1 15.0 12.2 16.8 14.5 19.4 18.4 8.0 26.1 15.2 16.8 16.4 12.5 12.3 6.4 8.5 26.6 17.3 15.8 4.2 3.7 10.9 14.3 17.0 14.8 13.8 12.1 15.3 35.8 12.0 6.3 17.1 7.8 12.4 10.5 7.8 22.0 15.9 15.4 28.9 30.1 19.0 18.6 10.4 18.1 23.9 32.1 18.9 27.7 19.0 13.8 11.3 17.3 39.0 22.7 11.8 33.9 8.3 19.9 9.8 24.7 27.1 66.8 14.5 13.2 17.1 25.0 17.4 17.1 5.9 27.1 12.6 19.6 109.1 16.9 173.4 7.2 35.9 26.2 15.0 19.3 8.0 9.2 32.7 21.9 49.0 5.2 9.4 12.1 7.7 29.6 30.4 10.0 25.7 7.4 12.5 17.2 93.1 33.1 33.4 30.5 31.1 14.1 12.2 19.6 33.5 46.7 64.7 0.0 12.8 5.9 1.7 21.0 1.0 1.1 1.1 0.9 8.9 0.9 1.0 1.3 28.6 3.1 24.4 2.2 2.4 5.4 14.9 13.9 11.6 15.7 14.5 19.4 16.8 16.4 17.3 15.3 17.1 15.4 32.1 6.4 6.0 11.8 5.5 8.2 5.2 4.9 8.6 8.3 7.4 9.9 11.9 8.6 4.1 1.8 2.1 16.6 5.1 1.4 3.9 5.2 2.0 3.0 9.4 42.2 6.0 5.5 11.6 5.1 10.0 8.4 3.1 3.8 3.8 10.4 56.4 6.5 20.6 8.4 12.7 4.2 6.1 37.0 22.0 1.5 7.2 23.4 7.2 18.7 30.9 4.1 6.2 12.5 6.8 7.4 1.1 6.8 5.0 7.4 2.6 4.4 4.0 6.5 6.6 17.2 8.2 14.2 13.1 8.5 5.7 3.0 6.4 7.1 4.5 6.6 PPP1CA "PP-1A, PP1A, PP1alpha, PPP1A" ENSG00000172531 "Protein phosphatase 1 catalytic subunit alpha" P62136 11 67398181-67421183 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism, Host-virus interaction" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004545, HPA046833" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB004545: AB_628177, HPA046833: AB_2679829" "unprognostic (1.03e-1)" "unprognostic (5.82e-3)" "unprognostic (1.10e-1)" "unprognostic (2.67e-1)" "unprognostic (2.09e-1)" "unprognostic (1.51e-2)" "unprognostic (3.15e-3)" "unprognostic (3.93e-2)" "unprognostic (2.07e-1)" "unprognostic (3.89e-2)" "unprognostic (5.05e-3)" "unprognostic (8.00e-2)" "unprognostic (1.66e-1)" "unprognostic (9.96e-2)" "unprognostic (7.69e-2)" "prognostic favorable (1.17e-4)" "unprognostic (7.60e-2)" 70.0 102.4 61.2 102.6 70.8 127.8 63.5 64.0 70.7 62.1 61.2 110.8 95.9 50.5 66.8 184.0 61.1 51.2 122.0 63.5 63.6 121.8 128.2 78.9 147.8 68.3 62.4 33.1 105.1 64.2 59.8 83.5 63.8 81.1 89.6 21.6 100.4 51.0 123.2 105.8 107.1 56.1 63.9 148.7 102.7 34.6 65.8 113.7 88.7 81.3 155.6 74.9 80.6 68.2 283.1 305.6 181.1 270.3 88.4 108.9 185.6 136.1 158.4 267.4 202.3 445.8 328.5 237.2 227.3 208.1 198.4 238.7 213.9 280.2 169.6 256.3 139.9 227.5 129.3 232.7 195.2 295.2 281.1 123.3 181.1 225.7 130.7 125.4 272.2 226.0 217.4 191.1 220.5 619.4 378.2 562.2 303.5 526.7 241.1 262.7 254.0 209.8 262.2 220.7 142.5 236.7 159.2 283.0 439.8 135.3 338.5 201.2 196.4 208.5 208.9 245.3 179.0 190.1 193.2 271.8 244.6 199.9 224.3 921.6 735.9 1234.1 779.2 962.9 604.3 733.4 679.9 792.5 705.3 779.6 412.6 584.2 853.8 688.8 1186.1 500.4 1098.7 2042.5 61.2 70.8 64.0 70.7 63.5 63.6 68.3 62.4 63.8 63.9 65.8 68.2 49.2 76.9 92.2 8.8 165.8 99.9 143.5 305.9 64.3 35.5 81.7 79.1 8.4 102.9 157.8 86.5 10.4 360.4 151.2 377.5 213.2 265.6 2.5 63.1 67.2 101.6 96.9 108.8 8.8 311.1 507.0 68.8 132.0 107.1 109.6 87.1 89.3 113.9 377.1 43.7 7.7 241.3 181.0 219.8 138.5 7.7 49.0 186.5 136.9 9.4 353.0 53.8 408.8 6.0 13.1 318.4 308.4 28.6 206.5 139.0 341.3 297.4 70.5 30.5 98.6 67.1 100.7 13.6 94.6 142.0 121.6 427.3 176.3 100.1 231.7 205.4 PPP1CB "MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta" ENSG00000213639 "Protein phosphatase 1 catalytic subunit beta" P62140 2 28751640-28802940 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Biological rhythms, Carbohydrate metabolism, Cell cycle, Cell division, Glycogen metabolism" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 985.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022558, HPA065425, CAB069426" Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3800000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB022558: , CAB069426: , HPA065425: AB_2685489" "unprognostic (2.90e-1)" "unprognostic (5.03e-2)" "unprognostic (5.49e-2)" "unprognostic (2.00e-1)" "unprognostic (7.08e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (6.52e-6)" "unprognostic (3.47e-2)" "unprognostic (2.44e-1)" "unprognostic (3.15e-2)" "unprognostic (1.54e-3)" "unprognostic (3.95e-1)" "unprognostic (1.68e-1)" "unprognostic (3.66e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-1)" "unprognostic (2.26e-2)" 90.9 75.2 55.8 74.7 73.5 119.1 110.5 55.6 74.9 148.6 67.8 109.2 84.8 138.4 104.0 245.7 113.5 103.1 185.2 54.3 73.8 84.4 70.5 73.3 60.4 73.9 61.2 92.7 76.2 126.9 45.9 74.8 74.5 149.1 92.9 70.8 114.6 123.4 386.0 73.7 76.0 159.7 71.8 65.8 81.7 47.6 63.5 71.3 78.8 262.8 91.1 118.0 104.1 88.2 186.0 114.6 391.1 121.7 130.8 121.0 227.0 97.7 110.6 92.2 91.0 102.6 106.9 147.5 119.2 101.5 102.7 111.4 112.6 129.9 109.8 235.9 58.2 111.3 130.1 111.5 284.3 127.8 50.5 93.5 181.3 100.1 207.8 97.4 113.8 77.0 103.6 140.4 123.3 93.2 136.9 110.3 128.3 141.8 89.8 132.2 344.9 112.7 304.3 220.6 106.7 131.3 151.4 166.2 136.2 111.4 80.4 70.6 137.6 122.6 134.6 89.3 119.0 100.4 171.0 299.8 130.1 135.0 93.5 72.4 59.4 84.9 39.8 96.7 50.8 38.6 59.3 46.8 65.4 31.6 51.8 58.8 103.6 61.4 115.2 49.8 74.3 52.8 55.8 73.5 55.6 74.9 54.3 73.8 73.9 61.2 74.5 71.8 63.5 88.2 172.2 93.0 80.6 59.4 147.8 492.1 176.7 101.5 64.9 62.4 208.0 117.0 352.1 112.9 124.1 310.8 27.1 129.6 210.4 324.5 244.6 297.0 514.0 330.2 245.7 129.3 283.0 200.2 68.5 210.5 202.1 147.8 78.5 258.9 146.6 91.2 137.8 108.7 114.7 163.2 71.8 144.2 111.9 182.6 985.1 406.2 196.7 238.1 336.2 59.0 137.9 116.6 55.6 64.3 68.4 236.8 181.3 302.0 100.9 364.9 106.6 227.4 213.3 65.2 631.1 225.8 264.8 55.2 66.6 135.6 458.0 392.9 237.7 65.8 154.4 498.9 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 208.9;Proximal enterocytes: 440.8;Proximal tubular cells: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 49.9" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA023755: AB_1854268" "unprognostic (9.63e-2)" "unprognostic (4.51e-2)" "unprognostic (5.45e-3)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (3.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.65e-1)" "unprognostic (3.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.45e-2)" "unprognostic (2.79e-2)" 6.1 15.0 10.2 4.7 8.6 3.8 8.2 4.3 15.0 10.5 16.7 25.1 27.1 10.5 1.6 9.8 18.9 3.1 9.6 12.9 8.9 26.7 23.5 10.8 2.9 10.2 10.4 7.9 17.7 7.4 36.9 1.7 7.1 15.5 2.4 2.9 11.6 5.6 6.3 9.0 24.6 1.6 8.1 8.0 14.1 33.3 10.3 2.4 27.0 1.0 1.0 9.1 6.7 5.1 30.4 24.3 3.9 15.1 1.6 2.7 19.3 8.2 5.1 6.3 5.1 6.4 21.2 5.0 21.1 3.0 5.6 19.8 2.0 6.7 1.0 10.3 11.9 6.0 26.4 6.8 4.7 4.3 7.9 2.7 8.9 7.3 2.1 4.1 4.5 8.2 24.0 6.1 2.3 49.9 15.3 19.9 7.4 15.6 30.3 15.9 1.9 10.1 5.7 10.0 12.5 23.9 14.9 13.7 13.0 1.0 32.3 9.1 7.7 7.1 33.2 19.8 15.8 4.0 4.3 1.8 22.8 8.3 6.5 0.0 0.8 0.0 1.0 1.2 0.9 0.8 0.8 1.0 1.2 0.1 0.5 1.1 0.2 0.2 1.7 0.7 0.6 0.8 10.2 8.6 4.3 15.0 12.9 8.9 10.2 10.4 7.1 8.1 10.3 5.1 7.9 3.2 15.4 28.1 6.2 43.2 36.2 47.6 54.1 25.0 78.3 82.0 85.8 157.3 24.6 40.5 14.6 7.2 6.0 135.9 121.3 33.7 12.6 43.8 15.6 13.3 51.6 6.1 7.8 41.6 24.3 13.3 70.3 24.2 3.8 16.4 12.8 208.9 6.1 30.3 7.6 98.1 26.4 7.0 27.1 14.4 22.7 9.8 8.8 5.6 3.8 102.8 5.2 6.6 2.8 29.3 109.8 15.4 5.9 40.0 440.8 404.2 59.8 50.9 6.6 17.2 17.3 52.9 28.7 77.8 61.8 6.7 7.1 69.2 116.0 28.3 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP1R18 "KIAA1949, phostensin" ENSG00000146112 "Protein phosphatase 1 regulatory subunit 18" Q6NYC8 6 30676389-30687895 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 208.4;Kupffer cells: 164.4;Langerhans cells: 179.3;monocytes: 212.8;NK-cells: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 215.8;neutrophil: 169.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 215.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044745, HPA051000" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 11000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA044745: AB_2679070, HPA051000: AB_2681304" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.01e-1)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "unprognostic (2.90e-2)" "unprognostic (3.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (9.33e-2)" "unprognostic (4.76e-2)" 35.4 16.7 9.5 42.5 9.1 56.0 25.9 9.9 12.8 30.2 7.0 38.0 8.8 36.8 3.5 18.1 28.6 25.6 23.2 9.4 12.1 14.2 16.8 51.5 75.5 17.8 12.6 26.8 10.1 2.7 7.0 21.4 15.5 19.7 7.7 2.6 15.4 11.5 10.8 21.6 33.7 17.3 13.7 80.4 19.5 5.9 15.6 53.5 17.6 9.0 38.2 36.1 24.4 13.9 63.2 9.4 34.4 37.3 28.0 80.4 1.7 48.4 63.6 43.3 29.9 6.6 11.2 64.7 25.0 77.3 73.7 35.8 21.6 44.7 29.6 74.8 2.2 79.3 20.7 6.6 59.1 28.6 116.3 44.0 44.0 97.9 89.8 64.5 60.0 53.3 27.2 58.2 57.8 6.9 40.8 43.5 3.2 1.6 13.8 162.8 28.8 33.9 18.0 3.4 3.8 19.2 30.1 10.9 65.9 18.8 9.4 26.8 90.8 139.4 29.2 29.4 103.3 11.6 57.3 77.3 40.7 131.9 155.9 43.0 16.4 215.8 43.4 21.8 31.8 20.9 23.1 42.5 9.5 22.0 16.7 32.5 169.6 37.8 25.2 14.9 39.7 22.6 9.5 9.1 9.9 12.8 9.4 12.1 17.8 12.6 15.5 13.7 15.6 13.9 39.1 3.2 15.7 1.6 89.7 109.0 29.6 15.7 79.6 2.3 14.2 14.6 3.1 8.6 4.6 9.2 0.0 3.1 116.5 0.8 0.0 25.1 24.2 4.4 24.4 67.8 1.8 35.4 0.8 8.2 20.4 34.1 7.1 6.7 53.2 5.9 32.9 8.2 208.4 3.3 1.3 0.8 8.2 164.4 179.3 19.9 27.7 123.3 39.2 19.7 212.8 1.0 332.7 11.1 0.1 20.8 0.0 23.3 52.9 23.8 0.4 2.5 4.4 3.1 26.3 28.6 53.5 1.2 1.3 38.3 59.7 4.0 141.6 6.8 0.7 22.5 PPP1R27 "DYSFIP1, toonin" ENSG00000182676 "Protein phosphatase 1 regulatory subunit 27" Q86WC6 17 81833492-81835050 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skeletal muscle: 1205.9" "Group enriched" "Detected in some" 14 "Early spermatids: 56.5;Skeletal myocytes: 108.8" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "HL-60: 206.4;THP-1: 385.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042227, HPA048632" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA042227: , HPA048632: AB_2680469" "unprognostic (3.35e-2)" "unprognostic (1.12e-4)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (1.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.21e-2)" "unprognostic (7.07e-2)" "unprognostic (1.32e-1)" "unprognostic (5.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.98e-6)" "unprognostic (7.97e-2)" "unprognostic (1.21e-1)" "unprognostic (2.19e-3)" "unprognostic (1.30e-1)" 0.3 0.9 0.0 0.0 0.1 1.3 0.4 0.2 0.3 0.4 0.0 0.2 0.0 0.1 0.0 1.2 0.1 0.0 0.5 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.0 0.2 0.4 0.0 11.8 0.0 0.1 1.8 0.0 0.0 5.8 0.0 1205.9 2.1 0.2 0.0 0.0 0.2 0.1 0.5 0.1 0.1 0.4 47.6 0.0 0.1 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 206.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.2 0.0 0.0 385.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 1.2 2.9 1.3 2.4 0.6 0.0 0.2 0.0 0.0 3.0 0.3 1.6 0.0 0.0 56.5 0.9 0.7 0.9 1.2 0.0 0.0 0.5 2.7 0.6 0.0 1.5 0.0 0.7 1.1 1.2 0.6 0.0 0.0 1.1 0.0 0.0 0.4 5.7 0.9 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.3 4.7 0.2 0.2 0.2 0.0 108.8 0.5 1.7 0.6 1.2 0.1 1.4 0.2 0.2 1.6 0.5 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591604-101595021 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 80.8" "Group enriched" "Detected in some" 38 "Early spermatids: 399.2;Late spermatids: 198.3;Spermatocytes: 600.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047157 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Cytosol "HPA047157: AB_2679960" "unprognostic (8.81e-2)" "unprognostic (2.65e-1)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 80.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.1 0.0 0.4 0.1 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 399.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.3 10.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.2 600.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPP4C "PP4, PPX" ENSG00000149923 "Protein phosphatase 4 catalytic subunit" P60510 16 30075978-30085376 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043837 Supported Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA043837: AB_2678695" "unprognostic (1.20e-1)" "unprognostic (1.33e-2)" "unprognostic (2.68e-1)" "unprognostic (4.74e-2)" "unprognostic (2.16e-1)" "unprognostic (5.79e-3)" "unprognostic (3.28e-3)" "unprognostic (2.60e-3)" "unprognostic (3.82e-1)" "unprognostic (1.29e-1)" "unprognostic (2.52e-1)" "unprognostic (3.17e-2)" "unprognostic (1.98e-2)" "unprognostic (3.78e-2)" "unprognostic (9.36e-2)" "unprognostic (9.96e-2)" "unprognostic (1.88e-1)" 44.3 57.9 34.8 43.2 34.7 63.2 42.5 35.9 38.7 42.8 41.0 49.8 47.0 39.6 47.1 88.3 35.9 32.5 45.6 34.0 35.7 49.9 83.2 46.2 58.6 35.5 34.9 29.4 41.0 46.4 33.5 49.6 35.3 37.8 35.2 18.1 44.0 28.5 60.8 60.8 49.0 32.8 35.6 62.5 49.2 65.4 38.4 61.2 35.4 30.2 63.7 56.3 48.9 36.4 132.7 145.9 95.5 134.0 88.4 73.8 148.5 115.8 127.7 148.7 163.8 129.5 167.9 102.7 145.2 137.0 95.5 105.9 119.3 143.2 87.0 130.1 213.0 70.5 86.0 290.4 133.5 100.1 126.8 107.9 124.7 135.9 85.5 88.4 174.9 130.5 139.6 91.0 115.1 382.2 174.4 180.7 182.2 104.7 77.1 190.9 99.4 180.4 142.5 134.5 91.9 136.8 57.1 169.1 101.8 79.4 156.0 166.0 113.3 86.4 90.4 70.6 90.8 155.4 183.8 122.4 123.1 126.9 107.0 100.6 103.5 236.1 66.5 113.2 47.7 68.5 69.6 74.2 115.8 88.3 62.0 54.1 215.2 51.7 100.1 90.6 95.1 48.3 34.8 34.7 35.9 38.7 34.0 35.7 35.5 34.9 35.3 35.6 38.4 36.4 87.8 51.3 33.4 10.7 85.8 147.2 121.7 206.9 71.2 23.3 94.2 82.8 11.1 82.9 133.5 77.3 29.2 313.7 106.0 217.0 158.5 226.9 156.9 80.5 55.5 91.7 125.6 89.2 8.0 193.3 335.3 66.7 106.0 85.2 69.2 66.7 74.6 94.2 239.3 35.3 8.6 159.3 193.3 105.4 138.4 143.8 62.7 124.4 80.0 9.4 221.1 61.1 118.4 8.0 12.9 345.5 220.8 52.3 97.6 161.3 191.0 198.6 119.7 29.5 72.3 43.4 85.9 228.5 157.8 113.2 172.5 421.0 93.0 61.7 175.9 227.2 PPP6R3 "C11orf23, DKFZp781E17107, DKFZp781E2374, DKFZp781O2362, FLJ11058, FLJ43065, KIAA1558, MGC125711, MGC125712, PP6R3, SAP190, SAPL, SAPLa, SAPS3" ENSG00000110075 "Protein phosphatase 6 regulatory subunit 3" Q5H9R7 11 68460731-68615334 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 186.0;Oligodendrocytes: 213.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017183, HPA038467, HPA038468" Supported Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA 6600 "Cluster 49: Eosinophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "CAB017183: , HPA038467: AB_2676029, HPA038468: AB_2676030" "unprognostic (9.46e-3)" "unprognostic (1.45e-1)" "unprognostic (4.62e-2)" "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (6.19e-2)" "unprognostic (1.97e-2)" "unprognostic (1.11e-1)" "unprognostic (1.71e-2)" "unprognostic (3.33e-2)" "unprognostic (1.02e-1)" "unprognostic (2.38e-2)" "unprognostic (2.20e-3)" "unprognostic (3.29e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (1.54e-2)" "unprognostic (6.43e-2)" 28.7 28.0 20.4 31.1 26.7 53.0 31.1 35.0 23.1 27.2 29.4 33.4 27.3 30.9 23.3 32.6 26.2 30.7 32.9 20.0 21.9 29.2 31.9 28.1 37.0 24.2 23.4 38.4 22.7 42.9 24.1 34.7 24.8 32.4 33.5 33.8 28.3 26.1 48.8 29.9 31.0 34.5 21.8 32.9 30.0 36.9 23.1 44.4 43.9 49.0 36.6 32.7 26.4 34.6 72.8 83.6 85.0 59.6 44.5 44.9 66.3 62.0 59.7 70.7 64.2 148.3 71.3 83.4 59.4 58.1 74.3 66.6 94.6 70.2 92.3 81.4 40.6 96.1 83.0 49.8 42.6 92.3 82.5 44.8 46.1 72.6 78.0 39.6 65.3 65.4 83.1 59.7 51.1 96.5 92.8 70.8 42.9 142.1 49.5 86.1 116.0 80.9 46.9 103.8 47.8 57.4 88.5 68.8 128.7 70.4 102.4 48.5 65.3 69.1 65.0 74.4 53.4 47.1 71.2 107.0 50.1 40.1 75.1 14.5 9.9 13.2 11.8 13.3 11.4 11.3 12.6 11.7 6.4 12.8 13.7 12.8 14.1 10.1 15.8 13.2 13.2 6.8 20.4 26.7 35.0 23.1 20.0 21.9 24.2 23.4 24.8 21.8 23.1 34.6 41.5 44.8 37.6 134.8 39.6 33.1 25.4 17.6 25.6 49.8 32.1 24.9 42.3 25.8 33.1 27.6 56.3 19.4 36.6 40.9 15.6 15.4 65.8 33.3 33.1 31.0 30.5 35.6 133.3 16.7 17.0 29.8 36.7 43.1 27.8 31.6 29.6 25.3 17.5 26.9 155.0 29.6 16.2 24.9 27.6 24.8 31.1 29.4 21.4 163.9 22.1 28.6 17.5 186.0 213.6 23.9 36.2 31.6 35.9 37.9 29.4 16.1 25.9 50.2 19.7 29.0 30.2 33.8 31.0 29.2 35.5 32.8 38.6 28.6 26.5 42.2 PPTC7 TA-PP2C ENSG00000196850 "Protein phosphatase targeting COQ7" Q8NI37 12 110533245-110583318 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.43e-5)" "prognostic unfavorable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favorable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 18.8 25.5 6.9 16.1 7.3 52.3 13.4 12.1 11.1 15.5 8.3 15.7 13.4 14.3 6.4 21.6 11.3 15.0 40.0 6.5 14.1 21.5 21.0 15.6 20.7 12.7 12.4 13.1 13.2 30.6 8.4 10.7 12.1 12.3 16.7 15.6 17.8 13.4 88.7 21.5 13.2 16.1 9.2 15.2 11.9 14.0 13.0 18.4 11.6 140.0 18.4 19.0 19.1 7.4 24.3 13.6 11.4 12.0 27.8 24.3 16.3 10.9 14.3 11.7 11.7 15.4 9.3 42.2 11.1 10.8 16.7 23.0 23.1 25.3 23.5 30.9 19.1 37.5 14.4 16.7 26.3 41.8 29.6 21.0 40.7 16.6 48.4 17.4 22.5 28.8 28.3 11.7 19.2 6.3 37.2 35.7 16.1 13.0 25.0 30.7 15.3 25.8 48.7 26.7 18.4 14.2 20.6 28.2 24.4 11.0 13.4 22.1 25.9 10.7 11.5 32.8 18.6 33.5 40.0 46.7 18.0 22.6 21.4 0.0 0.6 0.5 0.8 0.5 0.8 0.4 0.6 0.6 0.4 0.7 0.7 0.6 2.1 0.6 0.4 0.5 0.5 0.2 6.9 7.3 12.1 11.1 6.5 14.1 12.7 12.4 12.1 9.2 13.0 7.4 14.1 22.4 28.3 16.0 35.7 91.9 53.1 33.9 56.9 8.6 20.2 12.8 105.4 12.8 36.0 9.2 14.6 7.5 28.2 36.7 17.6 7.7 29.7 34.4 20.4 22.3 16.8 7.8 15.5 8.2 8.4 26.1 12.8 63.3 23.5 8.6 15.4 29.5 17.4 13.5 19.8 15.2 30.5 28.3 97.6 33.2 11.5 30.8 33.8 21.5 31.9 4.8 20.6 19.1 11.7 14.6 15.1 9.8 28.2 57.3 16.5 13.1 35.4 23.8 13.1 22.8 22.4 15.9 24.1 57.1 104.3 6.7 28.7 8.2 17.2 77.5 PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 105.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 249.0" "Cancer enhanced" "Detected in many" "melanoma: 139.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "K-562: 834.1" "Not detected" "Not detected" "HPA045153, HPA068562" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA045153: AB_10797259, HPA068562: " "unprognostic (9.36e-3)" "unprognostic (9.74e-2)" "unprognostic (1.02e-1)" "unprognostic (3.87e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.41e-4)" "unprognostic (3.43e-2)" "unprognostic (4.00e-2)" "unprognostic (1.33e-1)" "unprognostic (6.52e-3)" "unprognostic (9.68e-3)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.48e-9)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (8.87e-2)" "unprognostic (1.26e-1)" 0.2 3.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.2 0.0 3.4 10.0 0.0 0.5 0.0 0.3 0.0 0.1 1.8 0.1 0.2 0.1 0.1 0.0 4.7 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.1 105.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.2 0.9 53.3 0.0 126.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.4 0.7 3.5 88.8 0.0 0.5 0.1 4.3 0.0 0.0 61.5 14.8 36.0 21.7 0.6 0.0 2.9 172.6 0.0 0.0 0.0 0.0 0.0 0.0 14.9 834.1 15.6 0.0 8.1 0.3 0.2 0.0 27.2 3.5 5.0 0.0 0.2 0.0 0.2 1.1 185.0 0.0 0.6 0.2 0.0 27.8 24.3 5.0 0.1 159.6 0.0 0.2 3.0 14.6 1.3 0.2 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 37.8 22.3 1.1 0.3 0.0 0.0 0.0 0.0 0.9 2.0 0.0 13.0 0.0 60.9 0.0 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 41.4 5.6 0.4 0.0 0.0 3.1 0.2 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.8 0.0 0.4 6.6 0.0 2.7 41.8 249.0 0.0 0.0 0.0 0.1 14.2 0.1 0.0 PRC1 ASE1 ENSG00000198901 "Protein regulator of cytokinesis 1" O43663 15 90966040-90995629 "Predicted intracellular proteins" "Cell cycle, Cell division" Oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.9;testis: 55.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 142.9;Extravillous trophoblasts: 68.3;Spermatocytes: 136.4;Spermatogonia: 74.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 34.4" "Lineage enriched" "Detected in many" 4 "granulocytes: 34.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA034521, HPA048816" Enhanced Supported "Nucleoplasm,Plasma membrane,Microtubules,Cytokinetic bridge,Midbody" Yes Yes "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Microtubules, Cytokinetic bridge, Midbody" Nucleoplasm "HPA034521: AB_10670169, HPA048816: " "unprognostic (1.14e-1)" "unprognostic (3.98e-2)" "unprognostic (9.21e-2)" "unprognostic (1.75e-3)" "unprognostic (2.39e-1)" "unprognostic (3.43e-2)" "prognostic unfavorable (2.11e-4)" "unprognostic (1.24e-3)" "unprognostic (3.86e-3)" "unprognostic (1.65e-2)" "prognostic unfavorable (2.76e-5)" "unprognostic (2.49e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-2)" "unprognostic (1.79e-1)" "unprognostic (7.90e-2)" "unprognostic (3.92e-2)" 7.4 6.2 6.4 10.0 6.1 89.9 6.4 10.3 8.4 8.1 5.0 16.3 10.6 5.7 2.3 37.6 6.0 3.0 6.9 5.6 4.9 5.6 4.8 9.0 16.9 4.8 5.2 8.1 8.9 2.6 3.6 15.3 5.2 4.9 16.5 4.9 9.5 1.5 4.1 20.1 13.0 9.4 4.9 12.5 11.7 55.0 4.2 43.0 4.3 2.3 24.9 4.8 13.7 5.6 167.9 199.9 164.8 113.6 16.8 28.7 87.5 237.8 139.3 257.2 195.3 134.6 158.5 65.5 91.4 151.9 156.9 220.9 188.8 101.2 240.6 118.7 206.4 135.6 263.5 123.5 4.1 71.4 109.0 7.7 12.8 145.8 146.9 56.6 146.4 100.5 114.0 132.4 241.1 144.4 66.9 98.5 66.6 216.4 84.9 69.7 205.1 86.3 115.3 123.6 151.2 118.9 225.4 121.9 82.7 112.3 149.1 127.1 91.2 168.2 146.0 140.5 345.1 43.5 127.7 80.0 74.5 162.0 265.3 34.4 0.6 2.9 0.6 0.1 0.4 1.1 1.3 1.3 2.4 0.5 1.2 0.4 0.4 3.0 0.3 2.6 8.0 1.0 6.4 6.1 10.3 8.4 5.6 4.9 4.8 5.2 5.2 4.9 4.2 5.6 2.5 0.0 3.1 1.3 6.8 16.6 6.6 8.0 2.2 6.4 3.4 4.3 3.2 0.0 7.6 3.7 0.0 45.5 2.8 16.5 0.0 3.2 41.5 4.5 4.0 4.7 5.4 142.9 5.0 2.9 68.3 7.2 16.3 6.8 8.9 13.2 9.3 2.1 21.5 3.3 5.2 17.0 10.2 8.7 15.0 15.4 3.7 5.2 3.6 1.9 5.5 3.8 4.1 2.0 1.7 2.3 3.2 1.9 17.5 5.9 2.0 0.1 3.2 4.6 6.6 7.4 10.9 136.4 74.2 38.0 14.2 14.6 6.8 0.4 24.1 6.7 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PRIMA1 PRIMA ENSG00000175785 "Proline rich membrane anchor 1" Q86XR5 14 93718298-93788485 "Predicted membrane proteins" "Neurotransmitter degradation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.7" "Group enriched" "Detected in some" 9 "Muller glia cells: 35.5;Oligodendrocytes: 54.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HAP1: 5.2;Hep G2: 3.3;NTERA-2: 2.3;SCLC-21H: 8.3;SH-SY5Y: 8.2" "Region enhanced" "Detected in many" "basal ganglia: 18.1" "Low region specificity" "Detected in all" "HPA046671, HPA060047" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Nucleoli, Cytosol" "HPA046671: AB_2679744, HPA060047: AB_2684194" "unprognostic (3.60e-2)" "unprognostic (1.97e-1)" "unprognostic (7.54e-2)" "prognostic unfavorable (6.99e-5)" "unprognostic (1.03e-2)" "unprognostic (3.73e-2)" "unprognostic (1.07e-1)" "unprognostic (5.81e-2)" "unprognostic (2.93e-1)" "unprognostic (1.05e-1)" "unprognostic (8.94e-2)" "unprognostic (6.61e-3)" "prognostic unfavorable (2.62e-7)" "unprognostic (2.33e-2)" "unprognostic (2.67e-1)" "unprognostic (7.94e-4)" "unprognostic (4.57e-3)" 5.8 3.0 6.1 2.9 11.3 0.0 3.8 10.8 12.3 17.5 2.5 53.7 2.1 13.9 2.1 8.0 18.3 1.6 8.8 5.2 7.9 2.5 0.8 1.0 0.1 17.1 11.3 5.4 1.3 0.0 0.7 1.0 14.7 15.6 3.7 5.7 5.0 5.0 0.9 3.4 21.6 8.1 12.7 0.2 20.0 1.7 9.1 0.2 1.7 1.4 2.3 11.0 14.4 18.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 5.2 0.0 0.0 0.1 0.3 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.3 8.2 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 11.3 10.8 12.3 5.2 7.9 17.1 11.3 14.7 12.7 9.1 18.4 0.2 0.0 0.0 1.3 0.0 0.5 1.0 0.3 0.6 2.6 0.4 1.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.1 0.4 0.2 0.0 0.0 0.2 0.0 0.0 3.4 2.6 0.6 0.0 0.0 1.8 0.0 0.1 0.0 0.2 0.0 0.0 0.0 1.0 1.2 2.8 0.1 0.0 0.0 0.0 35.5 0.0 2.0 54.7 0.1 0.0 0.0 1.2 0.7 0.0 0.1 0.0 0.3 0.0 4.9 0.3 0.7 1.4 0.6 0.3 0.0 0.0 0.0 0.0 0.1 PRKCA "PKCA, PKCα" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.8" "Cell type enhanced" "Detected in many" "Astrocytes: 564.8;Excitatory neurons: 247.6;Inhibitory neurons: 400.0;Microglial cells: 281.1;Oligodendrocyte precursor cells: 849.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 157.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 190000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 3.1 21.1 37.0 6.9 35.0 1.8 2.3 20.8 51.4 7.5 11.8 18.5 11.9 11.7 4.8 3.2 4.6 7.5 4.4 76.8 32.8 12.8 7.3 4.5 4.9 37.3 36.1 15.7 5.1 0.9 6.3 5.0 25.3 13.0 8.6 30.1 2.3 16.9 5.8 3.0 10.6 10.7 30.1 6.5 8.4 2.6 36.9 3.1 3.2 4.3 4.6 8.9 5.6 27.3 7.3 38.0 7.7 7.8 18.2 46.0 1.0 40.8 26.4 28.8 24.3 4.5 4.6 9.6 10.9 65.9 48.1 0.9 3.9 4.8 61.9 16.4 9.3 0.0 22.2 20.2 24.9 12.2 62.8 20.2 1.8 36.0 30.5 41.8 25.0 45.6 25.8 0.2 44.8 2.3 24.9 7.4 3.1 18.9 20.2 4.5 56.5 0.2 10.2 6.4 4.6 25.6 13.5 7.7 0.4 8.0 0.8 17.0 75.1 49.6 28.6 31.4 25.8 0.1 0.0 1.2 157.6 0.1 25.1 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.8 0.4 0.3 0.0 1.2 0.7 0.0 0.0 1.1 0.4 0.1 0.3 37.0 35.0 20.8 51.4 76.8 32.8 37.3 36.1 25.3 30.1 36.9 27.3 10.0 0.0 8.4 564.8 5.7 10.6 15.0 10.3 13.6 198.3 7.9 11.2 9.8 45.8 7.2 40.5 2.1 4.1 24.6 27.1 7.9 16.1 3.2 5.5 40.1 5.6 8.4 5.7 247.6 6.8 3.4 17.5 23.9 6.3 20.3 39.9 27.8 14.7 25.4 10.1 400.0 38.4 2.0 11.9 7.6 3.0 53.4 20.9 10.6 281.1 6.8 34.3 12.3 849.0 198.3 8.8 21.0 48.5 11.8 12.8 27.0 21.3 7.0 77.1 26.3 6.5 41.4 1.3 3.9 6.1 10.4 15.2 36.9 47.1 26.4 17.2 PRKCE ENSG00000171132 "Protein kinase C epsilon" Q02156 2 45651345-46187990 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Cell adhesion, Cell cycle, Cell division, Immunity" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 34.5" "Cell type enhanced" "Detected in many" "Early spermatids: 206.5;Excitatory neurons: 394.4;Inhibitory neurons: 531.9;Late spermatids: 456.4;Oligodendrocyte precursor cells: 147.8" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 18.5;basal ganglia: 20.0;cerebral cortex: 34.5;hippocampal formation: 33.1;white matter: 17.1" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "REH: 27.0;TIME: 26.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001948, HPA008236, HPA044496" Enhanced Supported Supported "Vesicles,Plasma membrane,Intermediate filaments,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 58: Brain - Synaptic function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Intermediate filaments, Cytosol" "Vesicles, Plasma membrane" "CAB001948: , HPA008236: , HPA044496: AB_2678959" "unprognostic (1.10e-1)" "unprognostic (1.78e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.42e-4)" "unprognostic (9.61e-2)" "unprognostic (5.70e-2)" "unprognostic (1.51e-1)" "prognostic favorable (9.62e-4)" "unprognostic (3.05e-1)" "unprognostic (6.72e-2)" "unprognostic (7.49e-3)" "unprognostic (9.99e-2)" "prognostic favorable (2.63e-7)" "unprognostic (1.21e-1)" "unprognostic (7.11e-2)" "unprognostic (6.43e-3)" "unprognostic (2.23e-2)" 4.4 5.6 18.5 3.7 20.0 8.0 4.2 5.5 34.5 4.6 0.0 5.7 2.6 4.4 2.3 4.1 5.7 3.0 6.2 33.1 0.0 10.0 12.5 20.1 5.7 6.0 0.2 2.8 3.3 9.4 5.2 8.3 4.4 2.9 3.3 15.4 2.7 3.0 7.6 2.7 3.5 4.1 0.0 3.9 4.1 7.6 1.1 3.1 4.9 5.3 4.2 4.9 3.4 17.1 7.7 2.7 3.8 3.8 5.8 6.7 3.1 4.9 9.5 4.3 4.5 0.7 7.0 11.3 4.8 5.5 6.1 1.8 2.5 2.8 6.1 6.9 4.4 0.1 1.8 1.5 6.5 0.9 3.8 5.8 3.0 6.5 4.7 3.6 16.0 2.4 1.6 2.6 5.0 3.8 3.8 0.5 1.3 4.2 1.4 27.0 18.3 12.4 3.9 5.1 2.6 5.7 2.4 7.6 17.1 1.4 6.1 2.6 26.8 8.2 8.5 6.1 5.1 0.0 0.0 9.3 6.7 6.3 8.4 0.0 0.5 0.7 0.3 0.1 0.4 1.5 0.2 0.2 0.8 1.8 0.5 0.1 0.1 0.4 0.6 0.3 0.0 0.3 18.5 20.0 5.5 34.5 33.1 0.0 6.0 0.2 4.4 0.0 1.1 17.1 12.6 6.4 9.2 90.4 20.7 5.0 8.4 5.0 9.1 55.3 6.4 5.7 11.9 8.6 17.2 11.0 14.6 0.5 9.3 6.1 3.9 3.7 206.5 6.8 7.0 13.8 7.7 0.4 394.4 3.8 7.2 8.7 11.2 6.9 7.0 2.9 13.2 12.5 2.8 11.8 531.9 5.8 0.0 19.0 10.7 456.4 5.3 11.5 14.2 70.3 9.4 6.5 1.0 147.8 96.0 3.6 2.9 6.0 4.2 5.3 4.1 30.2 19.3 7.6 13.1 2.9 6.4 2.8 2.3 9.0 4.8 2.9 6.8 1.2 6.2 8.8 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PROM2 ENSG00000155066 "Prominin 2" Q8N271 2 95274449-95291308 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 88.1;skin 1: 60.0" "Cell type enhanced" "Detected in many" "Cholangiocytes: 37.1;Club cells: 39.9;Collecting duct cells: 33.1;Squamous epithelial cells: 37.2;Urothelial cells: 37.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 79.5;CAPAN-2: 135.9;HaCaT: 73.2;hTCEpi: 78.4;MCF7: 62.1;RT4: 83.8;SK-BR-3: 117.7" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB046005, HPA063728" Enhanced Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "Cell Junctions" "CAB046005: AB_2284371, HPA063728: AB_2685104" "prognostic unfavorable (2.16e-4)" "unprognostic (1.60e-1)" "unprognostic (1.41e-1)" "unprognostic (1.86e-2)" "unprognostic (1.76e-1)" "unprognostic (7.30e-2)" "unprognostic (2.23e-1)" "unprognostic (1.70e-2)" "unprognostic (1.37e-1)" "unprognostic (1.12e-1)" "prognostic unfavorable (2.90e-4)" "unprognostic (1.26e-1)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.46e-2)" "unprognostic (4.59e-1)" "unprognostic (5.24e-2)" "unprognostic (2.50e-2)" 0.7 0.3 1.1 1.5 1.3 0.3 10.3 1.0 2.1 16.6 0.2 11.4 10.5 1.9 27.9 88.1 5.5 27.0 1.1 0.9 0.6 32.4 0.8 1.7 0.1 1.4 0.7 1.1 10.2 25.5 1.5 4.5 1.2 24.7 9.8 0.4 35.2 27.7 0.7 60.0 4.8 0.8 0.3 0.6 26.3 0.6 1.4 2.0 11.9 0.2 7.9 25.7 37.9 2.1 79.5 0.1 0.2 0.8 0.3 0.1 38.5 0.1 0.2 0.3 0.4 0.8 135.9 0.0 0.0 0.1 0.1 73.2 0.0 42.4 0.4 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.3 0.0 78.4 0.1 0.4 1.9 0.0 0.1 0.0 0.1 0.0 62.1 0.4 0.5 0.1 3.7 0.5 0.2 0.0 0.1 0.2 83.8 0.6 0.2 0.0 117.7 0.1 0.9 37.2 0.1 0.0 0.2 0.4 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.3 1.0 2.1 0.9 0.6 1.4 0.7 1.2 0.3 1.4 2.1 0.4 3.2 4.2 1.3 0.1 6.6 25.2 27.6 14.2 0.4 29.1 14.9 1.7 37.1 39.9 33.1 4.2 19.0 0.1 8.0 11.7 15.6 0.5 2.7 0.6 0.9 3.6 0.0 0.6 11.0 3.5 0.6 25.5 5.5 0.0 0.7 0.0 0.0 2.4 0.0 1.2 10.4 12.2 0.0 0.8 1.4 0.3 0.2 7.2 0.0 0.6 0.1 0.0 1.5 3.2 17.5 12.4 0.7 0.0 14.1 0.7 0.1 12.3 1.1 0.0 0.4 2.2 0.6 0.1 37.2 12.8 11.2 0.2 0.8 17.4 37.5 PROSER2 "C10orf47, MGC35403" ENSG00000148426 "Proline and serine rich 2" Q86WR7 10 11823339-11872277 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 28.4;Glandular and luminal cells: 28.4;Hepatocytes: 31.2;Prostatic glandular cells: 34.6;Urothelial cells: 69.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 86.5;CAPAN-2: 99.5;HBEC3-KT: 64.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 14.4" HPA041337 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA 220000 "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA041337: AB_10794663" "unprognostic (2.36e-3)" "unprognostic (1.39e-1)" "unprognostic (3.55e-2)" "unprognostic (1.19e-1)" "unprognostic (4.60e-2)" "unprognostic (7.60e-3)" "unprognostic (4.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (1.25e-3)" "unprognostic (1.61e-1)" "unprognostic (1.26e-2)" "unprognostic (4.04e-2)" "unprognostic (3.01e-1)" "unprognostic (5.06e-2)" "unprognostic (8.69e-2)" 4.5 1.6 1.9 1.0 2.0 10.4 4.1 1.4 1.6 3.6 4.8 3.1 1.2 3.4 0.5 9.9 3.8 1.7 1.8 1.7 1.8 14.0 41.0 9.8 0.3 1.9 2.3 2.4 7.5 0.5 1.9 7.2 2.0 9.1 1.8 0.1 6.9 2.2 2.0 5.1 1.7 1.0 1.7 7.3 6.6 6.1 3.1 1.9 6.7 0.4 2.8 4.0 6.0 1.3 86.5 12.1 0.7 0.3 2.5 3.1 4.9 3.8 1.8 3.0 1.5 28.1 99.5 0.0 15.1 0.3 1.3 22.1 8.4 64.2 1.5 0.1 20.3 9.8 4.8 18.4 14.2 0.0 5.9 3.6 13.6 17.8 19.9 0.3 9.2 1.6 15.0 0.1 4.3 11.7 0.0 3.2 5.3 11.3 6.9 13.9 11.3 0.0 6.6 4.2 0.1 1.1 6.5 24.9 11.1 4.1 13.1 5.3 6.8 0.1 19.7 33.2 0.4 0.0 0.2 0.1 0.1 3.4 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 1.9 2.0 1.4 1.6 1.7 1.8 1.9 2.3 2.0 1.7 3.1 1.3 3.0 9.6 5.9 1.3 0.0 5.7 28.4 8.2 8.6 0.0 5.5 5.2 1.1 18.6 6.5 5.5 0.0 5.5 0.2 3.2 5.9 11.6 3.0 18.6 2.8 3.7 1.8 2.5 0.7 3.8 18.3 3.6 6.1 28.4 0.0 1.9 1.1 31.2 0.8 0.0 0.7 1.3 2.0 0.3 0.7 3.0 1.8 3.7 3.6 6.5 0.1 0.1 0.0 0.5 0.4 20.0 1.5 4.5 0.0 34.6 0.2 0.8 6.8 0.1 0.0 0.6 1.3 3.7 5.6 4.6 4.7 0.7 0.5 0.7 2.6 69.4 PRR15 ENSG00000176532 "Proline rich 15" Q8IV56 7 29563835-29567293 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 62.6;intestine: 81.4;stomach 1: 49.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 263.0;Granulosa cells: 194.2;Proximal enterocytes: 122.4;Respiratory ciliated cells: 63.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 38.7;HaCaT: 45.1;OE19: 97.7;RT4: 34.5;SK-BR-3: 74.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA040996, HPA048121" Enhanced Uncertain "Vesicles,Cell Junctions" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Vesicles "Cell Junctions" "HPA040996: AB_2677241, HPA048121: AB_2680271" "unprognostic (5.46e-2)" "unprognostic (1.27e-1)" "unprognostic (8.97e-2)" "prognostic favorable (6.37e-4)" "unprognostic (7.49e-2)" "unprognostic (1.96e-2)" "unprognostic (2.00e-1)" "prognostic unfavorable (7.23e-4)" "unprognostic (2.95e-1)" "unprognostic (2.45e-2)" "unprognostic (3.69e-3)" "unprognostic (1.25e-1)" "prognostic favorable (1.83e-6)" "unprognostic (1.30e-2)" "unprognostic (5.71e-2)" "unprognostic (2.33e-3)" "unprognostic (1.58e-2)" 6.5 0.7 0.6 4.8 0.4 1.1 9.2 0.1 0.7 62.6 0.0 81.4 72.3 18.1 21.6 1.0 9.0 7.8 1.3 0.4 1.0 16.9 0.3 2.3 0.4 0.6 0.4 5.9 3.0 1.4 3.0 4.8 0.5 2.5 52.6 0.0 7.5 3.1 0.2 0.3 72.4 2.3 0.6 0.2 49.3 0.9 1.3 0.1 1.1 0.0 0.7 16.6 0.5 0.6 16.8 23.3 0.0 0.0 8.7 10.7 29.3 0.7 1.1 0.4 0.2 20.5 38.7 0.0 4.1 5.5 0.6 45.1 4.9 0.0 0.0 0.0 3.3 1.3 4.5 22.7 2.8 0.0 0.1 0.1 7.3 0.0 1.7 0.0 0.1 1.5 0.0 0.0 0.0 3.9 0.6 3.2 3.5 97.7 18.5 0.1 0.0 21.4 26.5 34.5 0.5 0.3 2.3 74.9 0.0 12.8 5.4 0.0 19.9 0.5 0.0 0.1 0.9 1.8 3.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.4 0.1 0.7 0.4 1.0 0.6 0.4 0.5 0.6 1.3 0.6 1.8 0.0 0.5 0.0 0.4 0.1 1.2 11.0 0.0 0.0 10.0 7.1 0.5 12.8 16.4 38.6 0.0 14.2 0.2 263.0 29.4 6.9 0.8 31.3 2.3 1.2 8.4 0.0 0.1 21.8 9.9 1.3 16.8 34.7 0.0 194.2 0.4 0.2 2.7 0.0 0.0 45.3 26.4 0.0 0.3 0.1 1.5 2.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 14.4 58.5 2.2 0.1 3.0 122.4 14.4 63.1 0.0 0.0 0.0 7.8 0.0 0.4 1.2 0.0 6.3 0.6 0.4 56.9 23.3 PRR32 CXorf64 ENSG00000183631 "Proline rich 32" B1ATL7 X 126819729-126821786 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "tongue: 22.4" "Cell type enriched" "Detected in single" 13 "Cardiomyocytes: 1.3" "Cancer enriched" "Detected in single" 5 "glioma: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "basal ganglia: 3.5;hippocampal formation: 10.7;pons and medulla: 13.5;thalamus: 8.2" "Not detected" "Not detected" HPA048386 Uncertain Approved "Nuclear speckles,Plasma membrane,Centrosome" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Nuclear speckles, Centrosome" "HPA048386: AB_2680380" "unprognostic (7.10e-3)" "unprognostic (7.97e-2)" "unprognostic (3.79e-1)" "unprognostic (2.98e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.5 0.0 4.1 0.1 0.1 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 22.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PRR7 MGC10772 ENSG00000131188 "Proline rich 7, synaptic" Q8TB68 5 177446445-177456286 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 18.7" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 66.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "PC-3: 24.7;SK-MEL-30: 26.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA046636 Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA046636: AB_2679730" "unprognostic (3.69e-1)" "unprognostic (9.07e-2)" "unprognostic (1.16e-1)" "unprognostic (3.48e-2)" "unprognostic (4.08e-2)" "unprognostic (7.94e-3)" "prognostic unfavorable (1.50e-4)" "unprognostic (1.55e-1)" "unprognostic (1.01e-1)" "unprognostic (4.75e-2)" "unprognostic (5.86e-2)" "unprognostic (2.76e-2)" "prognostic unfavorable (1.98e-4)" "unprognostic (8.84e-3)" "unprognostic (2.22e-1)" "unprognostic (3.76e-2)" "unprognostic (1.69e-1)" 1.3 4.0 10.7 0.8 11.9 5.8 1.6 1.2 18.7 1.8 6.3 1.3 0.7 2.5 0.0 3.7 4.8 0.1 1.8 17.9 6.7 2.3 2.3 2.0 1.0 2.7 2.1 0.7 2.9 0.4 10.4 0.1 0.7 1.8 0.1 0.3 2.7 0.2 1.2 6.0 1.8 0.1 1.9 3.1 1.3 4.4 7.4 0.5 1.2 0.0 0.5 1.0 2.0 2.8 10.7 4.1 1.1 8.1 0.0 0.6 3.5 4.9 0.9 1.3 1.8 0.9 5.6 10.2 12.6 0.7 4.1 8.8 0.7 4.5 0.5 9.0 12.8 3.1 4.3 3.1 0.9 6.2 7.2 0.9 1.8 0.6 0.3 1.2 0.6 3.9 1.6 7.1 1.3 14.3 5.2 15.8 1.9 1.6 24.7 14.5 3.6 10.5 1.7 0.8 19.8 14.1 1.9 4.8 26.2 0.0 4.3 1.0 3.8 8.0 13.5 7.1 12.0 3.9 2.3 5.1 7.7 9.8 5.9 1.9 0.1 9.7 2.3 0.4 5.5 1.5 2.5 3.9 0.1 2.8 2.4 3.1 3.7 1.7 0.5 2.4 2.0 1.2 10.7 11.9 1.2 18.7 17.9 6.7 2.7 2.1 0.7 1.9 7.4 2.8 11.8 3.2 0.0 4.9 27.9 43.3 28.0 6.8 46.7 13.6 17.2 20.3 1.6 17.2 3.7 7.3 0.0 0.8 55.9 7.4 9.8 10.6 10.6 50.2 12.3 9.2 43.0 3.4 8.6 10.8 0.9 4.8 14.3 22.3 26.7 1.0 4.6 3.1 1.5 6.7 7.0 12.3 16.2 1.9 36.5 13.8 0.9 16.7 28.4 1.0 2.3 19.7 22.6 4.0 5.7 8.6 9.8 2.2 27.3 26.7 11.6 14.2 7.0 16.6 0.0 7.8 8.1 3.3 10.7 33.2 66.9 1.4 37.0 1.5 12.3 17.3 PRRC2A "BAT2, D6S51E, G2" ENSG00000204469 "Proline rich coiled-coil 2A" P48634 6 31620715-31637771 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 81.9;HEK 293: 148.3;U-266/70: 75.3;U-266/84: 86.8;U-698: 78.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB026383, HPA046791, HPA066501" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 5600 "Cluster 71: Testis - DNA repair" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "CAB026383: , HPA046791: AB_2679809, HPA066501: AB_2732747" "unprognostic (2.07e-1)" "unprognostic (6.84e-2)" "unprognostic (3.82e-1)" "unprognostic (2.25e-3)" "unprognostic (5.04e-2)" "unprognostic (4.63e-1)" "unprognostic (2.42e-3)" "unprognostic (2.09e-1)" "unprognostic (3.07e-1)" "unprognostic (1.14e-1)" "unprognostic (8.29e-3)" "unprognostic (2.38e-1)" "unprognostic (2.75e-1)" "unprognostic (1.01e-1)" "unprognostic (1.57e-1)" "unprognostic (5.40e-2)" "unprognostic (3.10e-1)" 37.2 36.5 0.2 6.8 0.2 0.1 36.3 0.2 0.4 48.8 0.0 47.9 0.5 53.7 12.2 42.0 47.3 0.0 41.5 0.6 0.2 37.4 23.0 36.4 3.4 0.6 1.0 55.7 35.1 0.0 50.4 0.8 0.1 47.5 0.6 2.9 31.8 0.3 54.9 37.6 37.3 0.1 0.2 41.7 37.1 84.3 0.2 4.3 41.9 0.0 0.0 44.1 40.3 0.2 4.4 19.3 0.2 0.7 35.5 33.6 3.3 2.0 0.0 0.0 0.2 0.9 0.2 4.2 24.5 41.8 0.0 1.8 0.0 81.9 0.0 8.1 148.3 4.6 0.2 0.3 0.1 2.0 1.4 14.9 0.0 0.2 0.0 0.0 0.0 30.7 2.0 0.0 0.2 0.7 0.9 0.2 0.4 0.1 1.7 2.2 0.6 0.9 6.9 0.5 2.6 1.3 1.5 0.1 0.7 0.0 0.3 1.5 0.7 0.5 17.6 1.3 0.9 75.3 86.8 78.7 25.7 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.4 0.6 0.2 0.6 1.0 0.1 0.2 0.2 0.2 39.3 0.0 5.5 25.5 39.2 32.9 28.4 26.1 67.7 36.1 41.6 39.0 6.7 18.6 14.5 40.5 60.5 26.9 38.0 48.4 5.9 24.8 58.7 33.3 37.1 33.4 38.9 47.9 19.2 25.6 22.2 32.9 52.0 35.9 10.8 55.5 33.5 22.5 34.6 37.0 19.7 39.1 26.4 28.2 30.9 23.7 49.0 31.4 19.6 15.9 28.7 20.9 39.1 23.1 15.3 34.5 37.8 44.8 47.2 39.1 27.0 16.0 20.1 35.9 19.7 57.0 44.8 58.0 43.2 64.1 28.4 18.3 38.2 45.3 48.0 28.4 PRRG1 PRGP1 ENSG00000130962 "Proline rich and Gla domain 1" O14668 X 37349309-37457292 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 39.4" "Cell type enriched" "Detected in many" 6 "Oligodendrocytes: 229.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 79.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078129 Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" Nucleoplasm "HPA078129: AB_2686878" "unprognostic (8.82e-2)" "prognostic unfavorable (4.65e-4)" "unprognostic (8.34e-2)" "unprognostic (2.08e-3)" "unprognostic (1.92e-1)" "unprognostic (5.11e-3)" "unprognostic (2.24e-2)" "unprognostic (7.23e-3)" "unprognostic (1.01e-2)" "unprognostic (1.74e-2)" "prognostic unfavorable (1.22e-4)" "unprognostic (8.21e-2)" "prognostic favorable (2.05e-7)" "unprognostic (1.43e-2)" "unprognostic (1.81e-1)" "unprognostic (1.08e-2)" "unprognostic (1.48e-1)" 8.6 3.7 12.3 2.1 24.9 0.2 5.2 21.6 19.7 4.4 4.7 4.0 2.9 4.3 1.5 4.1 2.6 8.8 6.4 12.9 15.9 10.5 7.9 5.5 1.7 26.7 21.3 4.2 1.6 1.2 1.4 8.1 25.3 3.4 4.1 1.5 2.9 7.8 15.9 2.2 3.0 5.4 18.4 2.9 2.4 1.5 18.4 1.5 8.3 7.8 1.0 5.6 3.8 39.4 32.3 7.2 5.6 5.6 18.7 15.4 2.4 14.1 17.6 4.7 8.2 17.1 20.2 0.0 21.8 10.4 8.9 10.7 15.6 10.0 8.3 0.1 5.2 5.2 7.7 5.7 22.6 0.0 7.2 23.2 8.1 9.1 7.7 9.4 24.8 0.0 2.6 0.1 16.5 2.4 0.1 0.1 6.8 5.1 13.4 0.0 13.1 0.0 79.2 1.7 0.0 0.1 9.7 15.6 6.1 15.3 0.1 3.5 17.6 7.5 4.2 14.2 4.1 0.0 0.1 0.0 7.3 0.0 7.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.3 24.9 21.6 19.7 12.9 15.9 26.7 21.3 25.3 18.4 18.4 39.4 29.7 6.4 4.2 15.7 0.0 11.3 4.8 7.6 5.2 2.2 5.3 5.3 8.1 15.7 2.7 33.1 0.0 7.0 0.2 7.6 7.9 6.8 0.7 3.3 12.9 18.4 3.0 0.0 23.3 3.1 14.9 9.6 4.6 9.2 1.3 3.9 17.9 16.3 4.8 18.5 10.8 5.7 14.2 4.1 5.3 0.4 4.7 1.4 3.6 31.9 0.8 2.2 0.0 12.5 229.8 18.7 7.5 2.6 0.0 9.1 4.3 9.4 2.9 0.5 6.6 8.3 8.4 2.5 4.2 5.2 6.3 10.4 0.4 3.5 4.8 8.1 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9945542-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 11.6;fallopian tube: 7.6;parathyroid gland: 15.3;pituitary gland: 11.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 17.2;MCF7: 23.1;SK-BR-3: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 83000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA035127: AB_10602822, HPA035128: AB_2674482, HPA069859: " "unprognostic (1.55e-1)" "unprognostic (8.41e-2)" "unprognostic (3.42e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-4)" "unprognostic (2.27e-3)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (2.20e-3)" "unprognostic (3.60e-1)" "unprognostic (1.01e-4)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (2.09e-1)" 0.9 1.8 3.9 1.1 5.0 1.5 1.2 10.1 11.6 1.3 0.3 1.3 0.4 1.2 1.2 1.2 7.6 1.1 1.1 4.4 1.1 1.3 0.4 0.9 1.2 5.1 1.9 1.3 1.8 15.3 11.0 0.3 5.3 2.5 0.3 2.2 2.3 1.7 1.4 2.3 0.9 0.9 0.0 0.9 1.1 2.1 3.6 1.3 2.2 0.2 1.3 1.8 1.1 4.8 0.4 1.0 3.6 4.7 17.2 2.3 1.2 1.8 3.4 2.0 4.5 0.3 3.4 2.0 0.4 4.2 2.1 0.3 1.3 4.5 0.9 9.8 2.0 0.7 1.9 0.2 1.7 0.4 1.7 4.4 0.3 1.7 0.7 9.7 0.8 6.0 1.0 4.7 2.5 23.1 4.4 0.4 8.5 0.1 2.1 2.8 0.4 1.9 1.0 0.4 6.6 4.4 1.8 33.6 0.7 1.4 9.1 0.4 0.7 0.4 4.6 0.9 1.3 6.1 6.6 0.6 10.9 0.3 1.3 0.5 0.2 0.2 1.2 0.1 1.4 0.5 1.3 1.2 0.0 0.6 1.4 1.3 0.3 0.7 0.1 0.6 0.2 0.4 3.9 5.0 10.1 11.6 4.4 1.1 5.1 1.9 5.3 0.0 3.6 4.8 3.3 0.0 2.0 3.9 2.9 2.7 3.8 3.7 3.4 22.8 7.4 6.2 3.0 7.2 3.4 11.0 14.6 0.7 4.4 4.5 3.9 2.9 4.3 5.0 5.4 3.3 11.3 2.1 14.7 5.0 0.5 5.2 5.6 4.9 1.3 7.9 2.2 2.9 3.8 15.2 10.8 5.4 2.0 2.5 2.6 3.5 5.6 2.2 1.8 2.8 11.3 8.6 11.3 5.5 3.7 3.1 1.0 2.6 2.2 4.2 6.4 8.0 12.4 21.6 0.0 7.2 5.3 10.4 6.4 3.4 2.3 0.4 5.6 7.8 4.7 3.0 PRRT4 ENSG00000224940 "Proline rich transmembrane protein 4" C9JH25 7 128350325-128361685 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adipose tissue: 16.3;bone marrow: 57.7" "Group enriched" "Detected in some" 7 "Bipolar cells: 4.8;Horizontal cells: 10.1;Inhibitory neurons: 12.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 225.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA046373, HPA052681" Uncertain Approved "Nucleoplasm,Peroxisomes,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Peroxisomes, Plasma membrane" "HPA046373: AB_2679642, HPA052681: AB_2681912" "unprognostic (1.72e-1)" "unprognostic (4.55e-2)" "unprognostic (5.36e-3)" "unprognostic (1.20e-4)" "unprognostic (2.60e-1)" "unprognostic (7.81e-2)" "unprognostic (1.88e-1)" "unprognostic (1.56e-1)" "unprognostic (5.62e-3)" "unprognostic (1.61e-1)" "unprognostic (2.48e-4)" "unprognostic (9.11e-2)" "unprognostic (3.73e-4)" "unprognostic (5.28e-3)" "unprognostic (9.09e-2)" "unprognostic (1.22e-2)" "unprognostic (1.27e-2)" 16.3 1.3 3.2 0.4 2.7 57.7 8.5 3.2 2.9 2.5 0.7 1.3 0.1 0.5 0.0 2.7 1.1 0.7 1.5 2.0 6.3 0.1 0.4 0.9 0.1 4.7 4.8 1.1 0.3 0.3 0.2 0.0 4.0 0.4 0.2 1.0 1.1 0.8 4.5 2.3 1.2 0.4 3.6 2.1 2.1 0.4 5.1 0.6 0.5 4.5 0.0 0.5 3.0 2.1 0.0 0.1 0.3 0.5 1.3 0.1 3.8 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.1 0.0 0.2 0.4 0.4 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.2 8.8 0.1 1.3 0.0 0.0 0.1 0.0 0.0 12.8 0.0 0.0 0.0 1.0 2.6 46.6 1.2 0.0 0.1 12.9 0.6 1.0 0.0 0.1 0.5 225.3 0.4 0.2 0.3 1.5 0.1 6.1 0.0 0.0 1.0 0.5 0.1 0.0 0.0 0.0 0.0 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 2.7 3.2 2.9 2.0 6.3 4.7 4.8 4.0 3.6 5.1 2.1 0.4 0.0 0.0 1.0 0.0 0.6 0.1 0.2 0.6 4.8 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.1 0.2 10.1 12.6 0.0 0.0 0.0 0.7 0.0 0.9 0.1 0.0 0.0 0.1 1.1 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 0.3 0.0 0.8 1.2 0.3 0.3 0.1 0.0 0.0 0.1 PRTG "FLJ25756, IGDCC5" ENSG00000166450 Protogenin Q2VWP7 15 55611544-55743152 "Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 10.4;thyroid gland: 10.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 191.8;Oligodendrocyte precursor cells: 51.8;Rod photoreceptor cells: 62.3" "Cancer enhanced" "Detected in some" "testis cancer: 1.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "AF22: 148.6;SuSa: 172.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA032138 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 12: NES - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA032138: AB_10669675" "unprognostic (2.80e-1)" "unprognostic (2.42e-2)" "unprognostic (1.32e-1)" "unprognostic (4.64e-2)" "unprognostic (2.07e-2)" "unprognostic (4.96e-4)" "unprognostic (1.82e-4)" "unprognostic (1.31e-1)" "unprognostic (3.19e-1)" "unprognostic (4.76e-3)" "unprognostic (1.37e-1)" "unprognostic (5.32e-2)" "unprognostic (5.67e-2)" "unprognostic (2.42e-6)" "unprognostic (8.81e-2)" "unprognostic (3.17e-2)" "unprognostic (2.70e-1)" 0.5 1.0 1.7 0.4 2.2 0.1 1.1 2.2 1.1 1.2 1.4 0.5 0.1 3.6 0.5 0.1 1.1 0.3 0.6 1.3 2.8 1.5 0.1 1.7 0.1 3.2 2.4 1.9 0.1 1.9 0.9 2.7 3.7 0.4 0.2 10.4 0.2 0.5 0.6 0.1 0.3 1.3 2.9 0.1 0.5 3.6 2.9 0.0 10.7 0.4 0.1 0.4 0.5 5.0 1.2 3.4 148.6 3.2 0.0 0.1 13.2 1.2 4.5 3.9 5.4 25.8 0.8 0.0 5.4 0.2 5.8 0.0 0.6 0.3 5.2 0.0 6.4 1.0 1.1 9.8 1.1 1.0 0.0 0.5 0.2 1.7 2.7 3.0 2.8 0.3 2.7 0.0 2.3 2.2 0.0 0.0 5.9 0.0 3.0 0.0 22.3 0.0 3.1 0.4 1.8 7.6 1.2 1.9 8.3 172.9 0.7 0.5 0.2 2.1 1.6 0.0 4.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.7 2.2 2.2 1.1 1.3 2.8 3.2 2.4 3.7 2.9 2.9 5.0 3.2 9.6 20.2 17.6 0.0 0.3 0.0 0.0 0.0 12.4 5.0 4.4 6.0 0.0 2.5 16.5 191.8 19.9 0.1 0.1 0.0 0.0 21.8 2.8 25.5 9.7 0.0 0.0 0.7 0.2 4.1 4.0 3.6 3.1 0.0 2.9 3.6 0.0 1.7 0.0 11.1 0.0 0.0 0.0 0.0 25.3 5.3 0.2 0.0 28.1 0.0 4.4 0.0 51.8 13.6 0.4 0.0 2.6 0.1 0.1 0.0 1.4 0.0 62.3 0.0 5.8 2.4 8.9 12.1 0.0 0.0 6.0 0.1 9.5 0.5 0.1 PRX KIAA1620 ENSG00000105227 Periaxin Q9BXM0 19 40393766-40414793 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Charcot-Marie-Tooth disease, Dejerine-Sottas syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 34.6" "Cell type enhanced" "Detected in many" "Adipocytes: 17.8;Breast myoepithelial cells: 23.2;Cardiomyocytes: 15.4;Skeletal myocytes: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Region enriched" "Detected in some" 8 "spinal cord: 114.2" HPA001868 Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus, Vesicles, Plasma membrane" "HPA001868: AB_2172440" "unprognostic (1.29e-2)" "unprognostic (3.04e-1)" "unprognostic (2.72e-2)" "unprognostic (9.72e-3)" "unprognostic (2.92e-1)" "unprognostic (1.74e-1)" "unprognostic (1.39e-1)" "unprognostic (3.54e-2)" "unprognostic (5.82e-2)" "unprognostic (3.23e-2)" "unprognostic (2.07e-2)" "unprognostic (3.28e-2)" "unprognostic (2.03e-3)" "unprognostic (4.42e-2)" "unprognostic (2.29e-1)" "unprognostic (1.38e-1)" "unprognostic (9.97e-2)" 4.5 4.7 6.2 1.3 6.8 1.6 3.9 5.2 6.5 4.8 2.9 3.6 1.1 4.4 1.0 2.0 4.2 1.8 3.1 4.7 4.4 6.7 1.0 34.6 1.3 5.4 4.9 6.2 3.8 5.9 1.5 5.1 6.7 4.6 0.7 0.8 3.8 3.5 4.9 3.2 2.2 2.0 4.9 2.0 3.7 1.6 5.7 0.7 9.6 5.5 0.8 4.3 3.1 4.1 1.6 2.6 2.1 2.7 1.3 4.4 2.6 1.4 1.5 1.9 1.4 1.0 1.7 0.5 1.6 1.3 1.2 0.9 1.0 0.6 0.7 0.8 0.9 0.3 0.3 0.5 2.1 0.1 2.3 3.3 3.2 1.2 1.1 1.7 1.6 2.9 2.0 0.5 1.0 2.2 1.0 0.6 0.6 3.8 1.7 3.2 1.8 1.5 0.4 1.8 0.2 1.0 2.7 2.3 2.0 0.9 3.2 1.2 1.4 3.8 2.9 1.6 0.8 5.3 5.0 0.7 1.1 1.2 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 6.2 6.8 5.2 6.5 4.7 4.4 5.4 4.9 6.7 4.9 5.7 4.1 17.8 3.2 5.9 0.7 1.4 6.2 2.3 0.3 5.7 0.1 8.1 23.2 15.4 2.8 0.9 1.8 0.0 1.1 1.7 1.0 0.0 0.3 0.1 1.3 1.7 9.2 0.0 0.4 0.6 0.6 0.7 7.0 0.0 3.0 0.0 2.0 6.8 1.3 1.1 0.0 0.5 0.7 2.0 1.6 2.5 0.1 3.4 2.5 3.6 7.5 0.3 3.3 0.0 0.0 0.5 0.5 1.4 4.5 0.9 1.7 1.2 1.9 0.2 0.1 0.0 30.3 6.1 0.3 0.7 5.0 4.1 2.7 1.1 1.3 1.5 1.0 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSD "EFA6, EFA6A, KIAA2011, PSD1, TYL" ENSG00000059915 "Pleckstrin and Sec7 domain containing" A5PKW4 10 102402617-102421539 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 233.9;intestine: 261.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 50.7;Cone photoreceptor cells: 95.9;Endometrial stromal cells: 47.7;Excitatory neurons: 41.1;Inhibitory neurons: 29.9;Rod photoreceptor cells: 70.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 7.7;MOLT-4: 4.4;SCLC-21H: 7.4;SH-SY5Y: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059237 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane, Cytosol" "HPA059237: AB_2683954" "unprognostic (2.43e-1)" "unprognostic (1.74e-1)" "unprognostic (5.62e-3)" "unprognostic (1.53e-1)" "unprognostic (3.16e-2)" "unprognostic (2.90e-2)" "unprognostic (7.73e-3)" "unprognostic (1.75e-1)" "unprognostic (9.59e-2)" "unprognostic (7.59e-2)" "unprognostic (2.24e-3)" "unprognostic (4.71e-2)" "unprognostic (1.52e-1)" "unprognostic (2.61e-2)" "unprognostic (8.50e-2)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" 1.2 9.1 159.5 3.8 151.7 0.7 1.5 7.8 233.9 53.8 0.0 261.8 6.1 78.3 1.4 1.6 46.2 8.9 4.4 220.9 63.9 2.8 2.4 1.2 0.9 23.8 25.4 15.3 5.0 1.5 99.4 0.8 27.3 4.3 3.5 36.8 1.0 1.2 0.4 1.6 41.4 17.7 14.9 1.5 44.2 12.4 70.2 1.4 1.1 0.0 0.4 105.7 14.7 87.6 0.2 0.0 3.0 2.7 1.1 0.6 0.3 0.2 0.0 0.1 0.0 2.1 0.3 0.2 1.8 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.2 0.1 0.1 0.1 1.6 0.0 0.1 7.7 0.2 0.5 0.1 1.2 0.0 1.0 0.4 0.7 0.0 1.7 4.4 0.2 0.4 0.3 0.0 1.2 0.0 0.1 0.0 0.1 7.4 6.4 0.1 0.1 0.2 0.2 0.5 0.4 0.0 2.2 3.5 0.2 0.0 1.9 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 159.5 151.7 7.8 233.9 220.9 63.9 23.8 25.4 27.3 14.9 70.2 87.6 0.7 3.2 0.5 6.8 1.0 0.6 0.3 0.3 0.0 50.7 1.1 0.5 1.5 2.8 1.5 0.0 95.9 0.2 0.6 0.8 1.9 0.2 6.6 4.8 47.7 1.0 18.0 0.0 41.1 1.9 0.2 4.0 2.6 1.8 0.0 0.4 0.0 1.3 0.7 13.5 29.9 0.9 0.0 0.6 0.7 2.7 3.7 0.5 0.0 3.7 0.1 13.2 0.0 9.0 2.4 0.7 1.4 4.1 0.1 0.4 1.3 1.2 0.5 70.8 0.0 2.0 1.1 4.0 3.7 0.7 0.1 0.7 1.9 8.8 1.3 0.1 PSD2 "DKFZp761B0514, EFA6C" ENSG00000146005 "Pleckstrin and Sec7 domain containing 2" Q9BQI7 5 139795808-139844466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 106.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 229.9" "Cancer enriched" "Detected in single" 43 "glioma: 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 1.1;U-2 OS: 1.1;U-698: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054625 Approved "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA054625: " "unprognostic (3.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" "unprognostic (2.48e-3)" "unprognostic (1.34e-2)" "unprognostic (5.01e-2)" "unprognostic (1.22e-2)" "unprognostic (6.55e-2)" "unprognostic (2.42e-1)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (4.02e-1)" "unprognostic (4.16e-3)" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (2.12e-3)" 0.1 0.3 70.8 0.3 91.3 0.2 0.5 86.5 63.1 0.8 22.0 0.2 0.1 0.2 1.6 0.0 0.4 0.2 0.2 58.7 76.3 0.1 0.1 0.1 0.0 90.6 106.2 0.1 0.4 0.0 0.9 0.0 79.2 0.2 0.1 4.1 1.7 0.4 0.3 0.1 0.1 0.1 70.5 0.2 0.1 1.1 106.3 1.0 0.1 0.0 0.1 0.1 0.2 56.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.9 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.3 1.1 0.0 0.0 0.2 0.0 1.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 91.3 86.5 63.1 58.7 76.3 90.6 106.2 79.2 70.5 106.3 56.3 0.0 0.0 0.0 229.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 9.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.5 0.0 2.6 0.0 52.8 24.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PSEN1 "AD3, FAD, PS1, S182" ENSG00000080815 "Presenilin 1" P49768 14 73136418-73223691 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Cell adhesion, Notch signaling pathway" "Hydrolase, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Cardiomyopathy, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 5 "Oligodendrocytes: 395.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB006844, HPA030760, HPA067496" Approved Supported "Nucleoplasm,Golgi apparatus,Cell Junctions" Yes No "Cluster 31: Non-specific - Inflammatory response" "Cluster 45: Intestine - Brush border" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus" "Nucleoplasm, Cell Junctions" "CAB006844: , HPA030760: AB_10696211, HPA067496: AB_2685853" "unprognostic (1.67e-1)" "unprognostic (4.79e-2)" "unprognostic (7.39e-2)" "unprognostic (8.68e-3)" "unprognostic (3.84e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (1.99e-5)" "unprognostic (1.65e-1)" "unprognostic (8.99e-2)" "unprognostic (8.45e-2)" "unprognostic (1.76e-3)" "unprognostic (2.74e-1)" "prognostic favorable (1.52e-8)" "unprognostic (2.29e-1)" "unprognostic (2.32e-1)" "unprognostic (7.12e-3)" "unprognostic (1.85e-1)" 25.1 22.6 44.3 26.5 80.7 39.6 28.2 62.4 56.0 28.1 48.9 49.5 50.2 25.3 26.9 35.2 22.9 31.7 18.0 47.4 51.6 35.5 31.9 32.1 22.4 73.0 63.8 22.0 22.9 35.1 11.6 43.1 71.5 24.3 46.3 23.4 22.9 23.4 18.4 38.2 49.0 27.1 55.7 22.6 31.0 32.5 60.8 26.2 36.9 23.3 30.7 35.0 19.2 119.1 37.1 55.9 50.6 20.0 68.9 49.9 46.7 52.5 60.1 52.6 66.7 69.9 88.9 23.7 34.1 50.5 43.0 94.9 43.2 40.1 57.3 54.6 26.7 27.1 35.1 34.4 63.8 27.7 50.7 50.4 71.9 44.3 54.4 48.5 43.2 26.2 31.0 46.6 50.0 72.8 21.0 35.7 22.0 64.5 40.4 26.4 42.7 30.2 73.7 76.5 28.1 38.3 57.4 53.0 47.1 45.4 66.3 60.7 45.7 53.1 43.5 44.1 25.3 30.3 47.9 23.7 44.9 32.8 33.3 126.8 94.5 96.3 23.1 106.0 22.6 23.1 22.3 19.0 83.4 31.8 20.7 20.1 129.3 42.8 125.0 43.6 37.0 70.3 44.3 80.7 62.4 56.0 47.4 51.6 73.0 63.8 71.5 55.7 60.8 119.1 22.2 28.9 30.5 35.9 25.8 28.6 24.6 24.7 12.0 17.1 25.0 17.7 12.5 15.7 30.2 23.9 39.6 27.1 30.7 79.1 5.9 27.1 22.9 26.3 26.4 22.3 16.2 12.0 38.9 26.7 29.2 23.7 32.1 47.4 18.3 29.6 15.7 24.6 30.5 13.5 40.2 39.5 24.4 50.5 40.8 12.9 16.4 52.3 16.0 39.4 51.8 13.8 14.4 48.7 395.8 38.2 58.8 15.4 23.6 38.8 76.2 13.0 29.0 28.0 26.3 20.0 19.0 40.2 14.4 20.4 33.0 49.9 21.6 18.6 41.3 51.5 PSMC5 "p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 596.6;Late spermatids: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA017871: AB_1857638, HPA064293: AB_2685234" "unprognostic (9.65e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-1)" "unprognostic (2.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (8.29e-3)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (9.54e-2)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" 90.4 99.0 134.8 80.9 137.5 82.4 80.6 141.3 159.0 79.6 130.2 106.1 68.0 80.1 112.3 104.9 83.2 59.4 107.5 136.2 139.3 120.9 112.7 68.1 93.0 140.5 140.2 63.3 71.0 161.1 82.5 75.5 141.2 81.4 84.4 85.3 73.4 86.7 236.2 121.5 70.6 90.3 137.7 82.4 84.5 73.3 139.6 93.3 86.4 168.7 108.0 93.4 79.6 138.9 240.1 369.1 233.9 172.9 171.4 174.7 202.8 225.3 197.0 327.1 243.8 390.3 154.7 158.7 154.7 241.6 246.0 182.8 239.1 228.5 383.5 136.8 289.7 330.3 288.9 362.4 180.1 336.0 230.4 177.5 171.4 291.9 266.6 139.1 263.7 180.9 258.4 210.2 284.9 450.7 279.4 237.4 215.6 266.3 330.0 248.9 445.5 244.3 249.0 270.9 203.2 274.1 158.6 313.9 152.3 254.4 306.8 197.8 238.8 360.3 329.9 161.5 482.6 220.5 335.2 250.4 225.8 255.7 241.5 105.1 120.4 149.4 164.1 176.3 222.8 142.7 191.6 179.3 140.0 122.0 161.3 183.1 37.7 167.4 206.3 108.6 272.1 216.1 134.8 137.5 141.3 159.0 136.2 139.3 140.5 140.2 141.2 137.7 139.6 138.9 97.9 51.3 78.6 8.5 82.7 94.6 145.0 206.3 71.7 84.9 71.1 79.1 156.0 110.1 139.6 68.0 18.8 250.4 85.1 98.8 246.5 195.2 596.6 75.4 69.4 104.7 90.9 107.7 7.9 214.5 187.2 101.4 69.3 68.1 90.2 53.3 86.4 130.9 162.9 72.3 7.9 92.7 197.4 89.8 85.0 1350.2 133.0 93.4 99.6 5.6 148.0 221.4 109.2 7.5 10.5 167.5 96.3 153.4 88.0 125.6 163.7 330.3 95.1 108.4 111.7 113.0 228.7 151.6 150.2 95.0 102.9 369.0 102.9 124.7 97.9 137.9 PSMC6 p42 ENSG00000100519 "Proteasome 26S subunit, ATPase 6" P62333 14 52707178-52728590 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042823 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No 300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA042823: AB_2678188" "unprognostic (2.38e-2)" "unprognostic (2.72e-2)" "unprognostic (9.18e-2)" "unprognostic (1.29e-1)" "unprognostic (1.19e-2)" "unprognostic (4.26e-3)" "unprognostic (3.14e-3)" "unprognostic (6.30e-2)" "unprognostic (1.06e-1)" "unprognostic (2.79e-2)" "unprognostic (3.50e-2)" "unprognostic (1.00e-2)" "unprognostic (1.52e-2)" "unprognostic (5.00e-2)" "unprognostic (2.68e-1)" "unprognostic (4.13e-2)" "unprognostic (4.67e-1)" 43.4 48.4 38.8 47.3 39.2 44.1 58.1 41.2 54.0 44.0 37.4 52.2 50.0 47.6 49.2 65.1 49.2 36.5 78.7 39.8 42.1 65.9 87.1 39.6 55.4 41.1 41.0 51.0 43.7 59.9 5.5 54.9 42.0 45.3 54.3 60.1 37.9 45.6 118.1 44.6 46.6 56.8 41.5 38.8 46.5 31.4 41.0 56.3 54.3 106.7 67.0 57.2 7.9 44.1 182.0 115.0 135.4 99.0 92.4 95.8 146.0 139.3 133.1 220.8 165.1 142.6 143.5 156.8 169.8 121.6 111.5 134.0 173.9 121.9 230.6 151.2 74.5 115.0 91.3 153.5 111.0 164.9 106.8 71.8 118.4 112.1 111.6 120.1 141.2 77.4 174.2 64.7 161.8 163.2 129.5 111.8 108.7 170.1 153.8 108.4 237.2 70.7 144.6 178.5 96.0 71.2 123.8 76.5 122.3 120.8 156.4 117.0 108.9 121.2 171.0 95.8 145.2 45.6 127.0 175.8 79.1 110.5 112.9 77.5 62.4 67.0 51.2 71.9 59.5 63.4 62.7 56.4 73.9 56.4 59.6 59.0 52.7 55.6 73.0 38.5 85.4 75.4 38.8 39.2 41.2 54.0 39.8 42.1 41.1 41.0 42.0 41.5 41.0 44.1 81.2 70.5 58.9 23.5 74.2 86.2 141.9 187.1 50.1 65.5 55.3 51.3 76.6 62.9 140.6 57.0 68.8 162.2 69.4 73.5 135.0 131.0 30.4 92.8 75.3 78.2 70.4 85.2 37.4 106.9 139.9 72.1 38.7 96.3 67.7 68.7 50.0 84.4 92.1 62.2 39.0 58.9 109.9 71.3 67.9 19.9 67.1 61.4 80.0 20.6 90.9 64.6 52.5 38.2 46.7 116.2 46.2 65.5 64.0 85.2 72.5 140.2 116.4 107.6 72.3 66.5 130.6 63.4 82.8 48.9 72.0 237.5 65.0 79.7 73.4 116.6 PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888732-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" NA NA 500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA040512: AB_2677014, HPA044220: AB_2678860" "unprognostic (2.24e-1)" "unprognostic (2.48e-3)" "unprognostic (2.12e-1)" "unprognostic (3.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (9.64e-3)" "unprognostic (3.17e-2)" "unprognostic (5.73e-2)" "unprognostic (6.19e-2)" "unprognostic (8.63e-2)" 16.5 4.6 7.5 2.3 8.1 19.2 4.8 8.0 10.0 5.8 11.8 13.8 11.5 7.1 2.2 6.2 6.4 3.8 5.5 7.9 8.1 10.8 4.6 6.0 5.7 9.0 8.9 5.9 10.6 4.8 3.5 3.9 8.3 4.6 2.2 3.6 8.8 6.7 18.5 5.9 6.2 3.3 8.3 8.9 14.9 5.1 8.7 6.6 5.1 6.0 3.2 4.1 5.5 9.4 54.8 81.8 6.7 12.2 11.2 11.6 13.9 54.5 17.8 27.3 15.5 60.0 6.3 40.5 45.0 28.6 9.2 22.1 20.0 29.1 16.3 78.5 41.6 33.3 40.9 30.5 27.5 23.3 22.7 20.4 14.0 30.4 11.7 9.9 16.6 24.7 30.1 5.3 17.6 63.2 47.1 17.8 14.0 7.1 63.4 35.6 18.3 24.9 13.4 53.9 14.1 19.3 54.4 7.7 29.3 5.8 23.3 11.3 43.3 25.4 29.0 50.1 38.4 30.4 73.0 62.1 45.5 30.1 23.8 41.8 43.6 53.0 33.9 46.2 27.3 47.6 32.6 31.0 38.5 38.5 25.0 21.2 41.3 29.3 41.7 63.7 48.1 51.6 7.5 8.1 8.0 10.0 7.9 8.1 9.0 8.9 8.3 8.3 8.7 9.4 22.8 48.1 33.7 10.1 32.6 60.5 11.4 64.1 67.2 7.3 40.9 34.8 8.0 34.3 40.0 35.0 18.8 30.3 45.8 66.6 52.8 116.9 34.9 32.6 28.7 29.7 46.6 121.4 12.9 121.4 30.7 30.5 42.8 27.4 44.4 11.0 33.9 26.8 39.8 15.2 10.7 66.5 54.9 37.9 55.3 11.4 37.9 43.6 55.2 7.5 93.9 17.2 35.0 7.1 18.7 138.2 64.2 38.7 73.2 9.5 146.8 100.7 36.6 14.8 39.5 19.5 46.8 33.9 37.5 69.4 71.6 37.8 44.9 12.9 67.7 12.8 PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 60.0;Enteroendocrine cells: 60.0;Hofbauer cells: 42.5;Kupffer cells: 41.8;Macrophages: 41.8;monocytes: 51.1;NK-cells: 91.6;T-cells: 68.4;Theca cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 55.1;HL-60: 14.4;NB-4: 20.9;THP-1: 14.7;U-937: 59.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" 6.0 2.6 2.8 11.7 2.7 56.6 2.3 2.7 3.1 2.0 3.4 3.3 2.5 1.6 0.1 2.0 3.1 2.9 2.4 2.7 2.8 3.4 3.4 10.4 13.5 3.1 3.1 1.0 1.3 0.2 1.6 1.8 3.0 2.9 0.8 0.1 2.4 1.0 1.5 1.8 9.4 1.4 3.1 33.9 2.9 0.7 3.6 4.2 2.9 1.0 5.5 4.3 2.7 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 55.1 0.0 0.0 0.0 3.3 0.0 14.4 0.1 0.2 0.1 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 20.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 4.0 0.6 0.0 0.1 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.1 0.0 0.0 1.3 2.4 0.1 59.8 0.0 4.8 71.5 71.4 39.9 33.5 30.8 13.3 27.2 32.7 59.0 18.5 14.3 22.3 85.3 41.6 38.3 5.2 27.0 42.2 2.8 2.7 2.7 3.1 2.7 2.8 3.1 3.1 3.0 3.1 3.6 3.1 1.1 0.0 5.1 1.0 19.2 9.3 1.2 0.4 0.0 1.1 0.9 1.1 1.9 0.0 2.5 0.0 0.0 0.3 60.0 3.1 0.0 0.0 9.6 0.3 0.3 0.8 60.0 4.8 0.4 0.2 0.7 1.9 0.0 0.3 2.5 0.1 2.2 0.9 42.5 0.0 0.1 6.1 2.0 41.8 36.5 18.6 0.9 41.8 7.2 0.0 51.1 0.2 91.6 5.5 1.0 0.1 2.5 2.6 8.5 0.3 0.3 0.4 0.0 0.4 0.0 0.8 3.1 0.2 1.2 0.2 4.8 0.5 68.4 78.1 0.3 1.2 PSTPIP2 ENSG00000152229 "Proline-serine-threonine phosphatase interacting protein 2" Q9H939 18 45983536-46072272 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "bone marrow: 72.4;lymphoid tissue: 63.4;skeletal muscle: 33.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 44.6;Erythroid cells: 46.7;Macrophages: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 112.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 102.0;HMC-1: 108.3" "Low region specificity" "Detected in all" "HPA040923, HPA040944" Enhanced Approved "Nucleoplasm,Plasma membrane,Mitochondria" No No 1500000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Mitochondria" Nucleoplasm "HPA040923: AB_10794429, HPA040944: AB_10795485" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" "unprognostic (1.21e-1)" "unprognostic (1.53e-2)" "unprognostic (2.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.17e-2)" "unprognostic (4.80e-3)" "unprognostic (1.87e-1)" "unprognostic (1.33e-1)" "unprognostic (5.83e-2)" "unprognostic (3.06e-1)" "prognostic unfavorable (2.39e-7)" "unprognostic (5.21e-2)" "unprognostic (3.55e-1)" "unprognostic (1.61e-1)" "unprognostic (1.93e-1)" 4.4 4.6 0.9 11.1 0.9 72.4 8.5 0.8 1.5 4.2 1.8 4.4 3.6 2.9 1.4 5.1 4.0 5.3 2.1 0.8 1.1 3.7 10.0 11.4 6.3 1.8 1.2 3.6 3.5 3.8 2.9 12.1 1.5 8.0 5.1 2.8 5.9 2.7 33.0 8.8 4.5 4.6 1.1 63.4 6.4 1.3 1.2 3.9 2.1 5.8 4.9 9.6 4.3 1.4 2.9 0.0 3.8 0.1 0.9 6.7 20.6 15.0 7.4 5.3 4.5 11.6 4.0 0.1 0.9 5.0 0.0 36.2 20.3 28.1 6.6 0.0 3.2 102.0 4.6 0.2 5.9 6.0 108.3 5.0 34.4 5.0 16.3 4.8 10.6 0.2 24.8 0.1 23.1 3.6 0.9 0.1 2.3 0.0 0.1 0.1 7.5 4.9 11.2 37.0 0.3 2.1 2.4 10.3 0.5 28.2 32.6 12.0 7.6 0.6 8.2 0.8 0.2 0.1 0.3 0.1 1.3 0.2 0.4 77.3 25.3 112.8 10.4 35.0 3.6 0.1 6.2 7.7 25.3 0.1 7.2 8.8 13.5 2.9 36.4 0.9 4.1 20.0 0.9 0.9 0.8 1.5 0.8 1.1 1.8 1.2 1.5 1.1 1.2 1.4 1.7 12.8 11.6 0.7 2.4 13.8 19.4 44.6 15.4 0.7 11.1 17.1 3.5 2.8 24.9 0.0 0.0 26.6 21.8 0.6 3.9 9.6 2.0 4.1 2.6 3.1 1.2 46.7 1.6 3.9 3.3 4.2 11.2 11.2 43.6 20.6 7.1 17.3 14.6 0.0 1.4 4.2 6.1 42.5 5.5 7.3 2.8 58.7 7.2 2.8 37.4 10.9 25.7 2.0 0.9 17.7 0.3 2.2 3.6 39.7 0.5 4.1 13.0 0.4 6.6 3.1 7.7 1.1 1.6 7.3 10.2 8.8 17.8 7.1 2.4 21.8 PTAFR ENSG00000169403 "Platelet activating factor receptor" P25105 1 28147166-28193936 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Chemotaxis "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 41.1;lymphoid tissue: 30.8" "Cell type enhanced" "Detected in many" "granulocytes: 75.4;Hofbauer cells: 71.7;Kupffer cells: 93.0;Langerhans cells: 67.8;Macrophages: 64.5;monocytes: 52.8;Pancreatic endocrine cells: 89.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 256.7;eosinophil: 906.5;neutrophil: 747.1" "Group enriched" "Detected in many" 5 "granulocytes: 906.5;monocytes: 256.7" "Group enriched" "Detected in some" 4 "HBEC3-KT: 36.6;HMC-1: 131.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA027543 Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles" "Plasma membrane" "HPA027543: AB_10610287" "unprognostic (2.22e-2)" "unprognostic (2.59e-2)" "unprognostic (6.73e-2)" "unprognostic (1.24e-1)" "unprognostic (2.75e-1)" "unprognostic (3.74e-2)" "unprognostic (1.07e-1)" "unprognostic (1.72e-1)" "unprognostic (3.35e-1)" "unprognostic (1.23e-1)" "unprognostic (2.39e-1)" "unprognostic (1.60e-1)" "unprognostic (2.79e-2)" "unprognostic (3.52e-1)" "unprognostic (2.59e-2)" "unprognostic (5.48e-2)" "unprognostic (1.38e-2)" 10.4 2.4 4.3 30.8 4.7 41.1 3.4 4.7 5.6 3.4 4.1 5.5 4.1 1.7 1.2 7.2 2.6 7.2 2.0 3.8 5.1 2.7 4.1 17.8 13.5 8.9 6.6 1.3 2.0 1.6 0.6 7.3 7.7 1.5 6.7 0.5 2.3 1.5 0.7 5.4 6.3 7.9 8.1 14.4 3.8 1.3 7.2 3.6 1.9 2.6 18.0 14.4 1.9 11.8 20.1 0.2 0.1 0.4 0.2 0.0 0.5 0.0 0.0 0.7 0.2 0.2 5.7 1.3 0.1 0.1 0.3 13.5 0.5 36.6 0.8 0.4 0.6 7.7 0.2 0.9 0.1 1.9 131.3 0.0 6.0 0.4 0.4 0.0 0.2 0.1 0.5 0.4 0.0 1.3 0.2 19.3 0.6 0.5 0.2 0.3 0.1 0.1 8.7 2.1 0.3 0.1 0.1 18.1 0.2 0.4 0.4 5.4 0.1 0.2 0.7 0.0 0.2 1.2 1.1 5.6 0.1 2.4 0.6 61.7 256.7 906.5 0.6 77.9 1.2 12.5 0.4 0.4 116.1 6.7 0.5 0.7 747.1 0.7 34.1 1.3 1.2 112.4 4.3 4.7 4.7 5.6 3.8 5.1 8.9 6.6 7.7 8.1 7.2 11.8 2.1 6.4 6.7 0.0 4.1 6.5 2.0 37.9 5.2 1.5 0.8 0.5 2.2 1.5 20.9 1.8 2.1 0.6 2.9 0.4 0.0 18.1 0.4 0.5 0.2 7.3 0.0 4.0 0.9 5.1 0.5 1.3 1.1 0.5 75.4 2.0 2.9 1.0 71.7 0.0 0.7 0.0 18.3 93.0 67.8 0.2 0.6 64.5 0.0 15.0 52.8 0.2 0.0 1.5 6.6 89.8 0.6 0.0 0.5 0.6 0.3 0.2 20.2 0.9 0.0 0.6 1.0 2.3 0.7 3.2 2.8 1.5 2.0 0.0 0.4 9.4 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTCHD4 "C6orf138, dJ402H5.2, FLJ41841, PTCH53" ENSG00000244694 "Patched domain containing 4" Q6ZW05 6 47856673-48111197 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 479.8" "Group enriched" "Detected in some" 6 "melanoma: 1.1;renal cancer: 1.6;thyroid cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;BEWO: 12.4;Hep G2: 21.8;LHCN-M2: 9.6;SuSa: 20.1;TIME: 9.9;WM-115: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041276 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA041276: AB_10796570" "unprognostic (1.35e-4)" "unprognostic (1.66e-2)" "unprognostic (3.25e-1)" "unprognostic (3.11e-3)" "unprognostic (1.07e-2)" "unprognostic (1.57e-3)" "unprognostic (7.94e-2)" "unprognostic (3.59e-3)" "unprognostic (2.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.49e-6)" "unprognostic (5.03e-4)" "unprognostic (9.84e-2)" "unprognostic (1.57e-2)" "unprognostic (5.56e-3)" 0.5 0.1 0.6 0.0 0.6 0.0 0.3 0.0 1.5 0.6 0.1 0.3 0.1 0.3 0.6 0.3 0.5 0.2 0.5 0.8 0.5 0.4 0.3 0.5 0.0 0.2 1.0 0.2 0.2 0.0 0.9 0.3 0.0 0.5 0.1 0.8 0.5 1.0 0.1 0.0 0.1 0.3 0.5 0.0 0.1 0.2 0.3 0.0 0.8 0.1 0.0 0.3 0.3 0.4 0.0 0.0 9.4 0.0 1.3 3.9 12.4 1.2 2.8 0.0 0.4 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.2 21.8 0.5 0.0 0.0 6.2 5.4 0.0 0.1 4.4 1.8 2.5 0.0 0.0 9.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.5 0.1 0.0 0.0 20.1 0.0 0.0 9.9 2.3 1.9 0.0 0.2 0.0 0.0 0.0 3.3 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.5 0.8 0.5 0.2 1.0 0.0 0.5 0.3 0.4 0.5 0.0 1.1 6.5 0.0 0.1 0.0 1.0 0.0 1.0 0.4 0.3 0.2 0.0 1.3 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 90.6 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 479.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 89.9 0.0 0.6 0.0 2.5 2.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 1.1 0.9 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;brain: 102.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 127.4;REH: 141.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favorable (5.11e-4)" "unprognostic (3.33e-3)" 19.7 10.8 46.9 52.6 54.4 106.3 11.5 22.8 102.9 11.5 38.3 29.8 34.1 9.9 8.9 19.2 15.6 12.7 10.6 96.3 8.5 15.9 15.2 28.6 78.3 0.0 26.0 4.7 12.6 7.1 13.7 8.0 0.0 25.5 23.5 4.4 26.6 12.3 5.0 45.2 48.8 10.7 0.2 78.3 22.2 9.5 27.0 86.0 12.5 5.4 73.6 21.0 15.1 37.0 38.2 10.4 2.8 3.0 76.6 5.5 21.5 2.9 1.9 1.9 2.7 9.9 21.5 127.4 4.0 5.8 3.1 34.3 1.1 31.3 1.1 8.7 0.8 26.4 10.6 2.0 15.7 28.5 45.5 41.6 46.0 2.6 17.3 13.0 1.0 36.0 31.7 85.6 2.1 4.0 49.1 57.0 2.2 33.0 2.6 141.2 0.7 88.3 8.5 29.5 19.2 3.5 13.4 9.3 5.0 6.5 11.5 72.1 17.5 1.3 2.8 2.5 1.0 68.0 32.0 68.9 5.2 60.6 2.4 47.3 48.4 36.9 33.9 43.0 22.2 46.0 17.0 24.3 36.1 46.6 20.8 25.9 45.8 29.0 53.5 11.7 18.2 50.1 46.9 54.4 22.8 102.9 96.3 8.5 0.0 26.0 0.0 0.2 27.0 37.0 6.9 3.2 29.8 16.6 64.3 37.7 38.7 19.7 6.8 5.4 5.9 7.7 3.7 8.6 13.0 14.7 0.0 2.9 33.4 65.5 0.0 8.0 1.2 7.1 1.8 9.6 7.8 20.2 109.2 8.3 26.5 3.5 22.4 5.3 28.5 1.1 5.0 24.1 23.1 8.4 9.2 21.9 10.2 68.4 32.1 1.0 1.5 55.3 8.8 22.5 62.5 2.8 70.0 7.5 15.1 13.3 42.0 0.7 68.1 18.6 44.6 16.1 13.9 3.9 0.0 3.3 3.3 4.2 6.4 4.8 30.1 1.9 46.6 1.0 18.1 17.9 PTK6 BRK ENSG00000101213 "Protein tyrosine kinase 6" Q13882 20 63528001-63537376 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 109.4;skin 1: 53.9;vagina: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 132.1;Gastric mucus-secreting cells: 59.1;Intestinal goblet cells: 42.5;Paneth cells: 97.6;Proximal enterocytes: 80.2;Squamous epithelial cells: 48.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 22.1;CAPAN-2: 41.4;HaCaT: 33.9;hTCEpi: 45.0;OE19: 57.0;RT4: 26.4;T-47d: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB032952, HPA036070, HPA036071" Approved Supported "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Nuclear bodies, Plasma membrane, Cytosol" "CAB032952: AB_634461, HPA036070: AB_10602292, HPA036071: AB_10669982" "unprognostic (2.32e-2)" "unprognostic (1.36e-1)" "unprognostic (1.05e-1)" "unprognostic (2.42e-2)" "unprognostic (1.41e-1)" "unprognostic (1.35e-1)" "unprognostic (1.04e-1)" "unprognostic (2.29e-1)" "unprognostic (3.03e-1)" "unprognostic (3.72e-2)" "prognostic unfavorable (1.96e-4)" "unprognostic (1.28e-1)" "prognostic unfavorable (1.26e-9)" "unprognostic (4.19e-2)" "unprognostic (1.74e-1)" "unprognostic (1.73e-1)" "unprognostic (4.24e-2)" 0.5 0.1 0.6 3.6 1.7 0.8 3.8 2.9 1.7 19.8 0.0 26.5 28.9 0.4 0.1 109.4 0.4 3.5 0.2 0.6 0.9 0.8 5.2 2.6 0.6 1.6 1.0 0.3 3.6 0.0 0.2 0.3 1.7 3.1 15.7 0.8 19.1 0.6 0.6 53.9 22.2 0.8 0.6 0.8 26.2 0.3 1.1 0.3 0.2 0.0 6.4 9.8 43.2 5.4 22.1 2.6 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.5 41.4 0.1 7.2 0.0 0.1 33.9 0.0 0.1 0.0 5.4 0.4 0.0 10.2 0.1 0.1 0.0 6.7 0.0 45.0 0.0 0.2 0.2 0.0 0.1 0.2 2.5 0.2 12.5 0.0 0.2 0.2 57.0 15.5 0.1 1.2 0.5 0.0 26.4 0.3 2.2 2.6 8.1 0.0 0.1 25.2 1.6 0.2 0.3 0.4 0.8 0.3 0.5 0.1 0.1 0.4 0.5 1.1 0.4 0.7 0.1 0.1 0.5 0.5 0.3 0.1 0.0 1.3 0.3 0.1 0.1 0.3 0.0 0.4 0.1 0.1 0.3 0.6 1.7 2.9 1.7 0.6 0.9 1.6 1.0 1.7 0.6 1.1 5.4 0.3 12.8 25.6 0.3 1.4 5.9 2.6 7.7 5.2 2.2 7.0 4.3 0.4 12.8 14.9 0.0 2.1 0.2 0.2 132.1 0.0 1.4 0.2 0.4 0.5 3.2 5.4 0.0 0.1 1.6 0.2 1.4 59.1 1.3 9.5 0.2 0.4 1.7 0.6 0.0 0.1 42.5 2.0 2.2 2.0 0.0 0.3 2.6 0.0 0.0 1.0 1.6 1.0 0.0 0.8 17.6 97.6 0.0 0.1 1.5 80.2 0.2 8.9 3.7 0.0 2.3 1.1 0.2 0.3 48.0 15.5 0.1 2.0 0.2 32.1 15.9 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 60.5 30.1 24.2 43.9 26.6 69.9 50.3 29.2 31.6 40.9 25.9 48.9 18.9 38.6 18.6 38.5 39.6 40.2 39.0 25.1 27.3 36.1 30.9 65.0 27.5 28.5 27.8 34.6 20.1 21.0 21.9 74.7 30.5 26.4 27.7 30.9 23.8 33.2 24.6 36.9 29.7 40.2 26.7 52.7 27.1 30.1 32.7 33.9 31.0 44.5 27.5 46.7 39.6 30.2 72.4 43.5 100.6 51.8 69.1 71.7 54.2 73.3 93.0 56.6 80.0 21.6 109.9 8.6 23.2 86.3 123.6 50.2 34.2 73.4 113.3 21.2 19.2 44.9 44.2 88.4 67.7 25.8 28.8 59.0 80.3 123.2 157.6 101.0 121.6 2.1 54.9 12.2 182.6 49.4 3.6 71.9 81.7 97.6 49.2 15.1 80.6 4.5 97.6 38.5 12.5 66.6 90.4 81.5 73.4 172.2 39.5 93.9 89.3 121.4 73.1 45.0 141.3 12.6 7.4 22.2 71.6 65.9 215.7 3.6 4.1 6.8 3.1 2.8 1.3 2.3 1.1 2.6 3.8 1.0 0.6 3.3 9.5 13.3 5.3 0.3 1.6 2.7 24.2 26.6 29.2 31.6 25.1 27.3 28.5 27.8 30.5 26.7 32.7 30.2 139.3 70.5 56.2 30.0 18.2 68.8 60.0 55.9 23.9 16.7 40.9 26.3 41.3 28.6 46.4 20.2 8.4 40.0 89.0 31.2 3.9 42.1 3.5 43.9 62.4 114.4 12.1 16.6 65.8 39.6 58.7 54.6 21.4 87.2 14.5 21.7 119.2 24.6 50.1 35.3 58.0 21.7 28.5 82.0 121.3 6.7 46.6 96.1 35.6 93.7 54.9 66.9 163.7 70.4 67.3 75.0 21.4 47.0 17.6 62.0 10.9 19.2 23.2 15.2 65.7 127.9 66.8 51.2 71.4 29.8 101.4 72.1 27.3 24.4 23.3 104.8 PTPN22 "Lyp, Lyp1, Lyp2, PTPN8" ENSG00000134242 "Protein tyrosine phosphatase non-receptor type 22" Q9Y2R2 1 113813811-113871753 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Autophagy, Immunity" "Hydrolase, Protein phosphatase" "Diabetes mellitus, Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;lymphoid tissue: 20.3" "Group enriched" "Detected in many" 4 "B-cells: 67.4;dendritic cells: 176.0;NK-cells: 108.1;Plasma cells: 79.6;T-cells: 151.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 69.3;HL-60: 27.7;U-266/70: 29.2;U-698: 37.5;U-937: 28.4" "Region enriched" "Detected in single" 11 "cerebellum: 5.3" "Not detected" "Not detected" "HPA004912, CAB012209, HPA013350" Approved Uncertain "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Nucleoplasm "Vesicles, Plasma membrane" "CAB012209: , HPA004912: AB_10602069, HPA013350: AB_10601570" "unprognostic (2.25e-2)" "unprognostic (5.31e-3)" "unprognostic (3.48e-1)" "unprognostic (3.33e-4)" "unprognostic (9.14e-2)" "unprognostic (2.47e-3)" "unprognostic (9.60e-2)" "unprognostic (8.14e-2)" "unprognostic (3.71e-1)" "unprognostic (1.82e-1)" "unprognostic (1.62e-1)" "unprognostic (3.02e-1)" "unprognostic (2.75e-6)" "unprognostic (3.19e-1)" "unprognostic (1.10e-1)" "unprognostic (1.61e-1)" "unprognostic (3.22e-2)" 2.0 1.5 0.2 11.5 0.2 38.0 2.3 0.4 0.5 1.8 0.6 4.0 6.4 1.0 1.1 1.7 0.9 4.8 0.6 0.1 0.2 0.6 2.0 7.5 20.3 0.5 0.2 0.6 1.3 0.3 0.3 0.8 0.4 1.0 4.3 0.4 1.3 0.6 0.3 0.9 8.6 1.6 0.2 13.2 5.2 1.4 0.6 20.0 0.7 0.2 13.5 4.2 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.9 0.4 0.0 0.7 0.0 0.4 69.3 0.1 0.2 0.0 0.0 0.0 0.1 0.5 6.5 0.0 10.0 0.0 0.0 0.2 27.7 21.1 5.7 0.0 2.8 0.2 5.1 10.6 17.2 0.1 15.7 10.3 0.2 20.1 15.7 0.0 0.1 0.0 1.2 6.7 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 10.0 5.0 16.0 0.3 0.4 0.5 29.2 6.6 37.5 11.1 28.4 0.1 15.8 4.8 25.0 17.0 1.3 20.1 9.9 8.4 13.6 8.7 7.4 5.0 12.1 2.4 11.0 0.6 5.2 14.5 7.3 0.2 0.2 0.4 0.5 0.1 0.2 0.5 0.2 0.4 0.2 0.6 0.8 2.2 0.0 6.5 0.7 67.4 2.5 0.2 0.0 1.2 0.7 2.2 2.4 0.8 0.0 0.2 1.8 2.1 0.1 176.0 2.2 0.0 0.1 0.4 0.7 0.5 1.7 0.0 16.6 3.2 0.6 0.3 2.2 12.8 1.0 27.8 0.0 0.4 0.5 7.1 0.0 2.5 1.2 0.0 17.3 26.8 1.0 0.0 26.4 3.6 2.8 14.4 0.0 108.1 0.0 1.7 0.5 0.8 0.0 79.6 0.3 4.3 0.1 2.2 0.5 13.1 0.6 1.4 0.4 0.6 0.3 2.7 0.1 151.2 0.0 2.2 0.3 PTPN4 PTPMEG ENSG00000088179 "Protein tyrosine phosphatase non-receptor type 4" P29074 2 119759922-119984899 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 37.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 224.3;Horizontal cells: 161.5;Inhibitory neurons: 187.5;NK-cells: 247.2;Oligodendrocyte precursor cells: 200.6" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 37.3" "Group enriched" "Detected in many" 4 "gdT-cell: 35.0;MAIT T-cell: 28.1;memory CD4 T-cell: 16.9;memory CD8 T-cell: 27.9;naive CD8 T-cell: 19.2;NK-cell: 24.4;T-reg: 11.0" "Group enriched" "Detected in many" 16 "NK-cells: 24.4;T-cells: 35.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019351 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 44: HDLM-2 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA019351: AB_1855928" "unprognostic (1.45e-1)" "unprognostic (1.22e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-2)" "unprognostic (9.00e-2)" "unprognostic (9.57e-2)" "unprognostic (2.34e-1)" "prognostic favorable (5.16e-4)" "unprognostic (3.31e-2)" "unprognostic (3.34e-3)" "unprognostic (3.13e-1)" "unprognostic (1.10e-1)" "unprognostic (3.34e-2)" "unprognostic (1.74e-1)" "unprognostic (1.87e-1)" "unprognostic (4.08e-2)" "unprognostic (1.81e-1)" 4.5 3.8 5.9 3.6 5.0 5.1 4.7 37.3 10.1 5.7 0.0 3.4 5.1 4.1 4.2 4.1 5.5 3.7 5.7 5.2 2.7 7.4 4.2 5.2 5.4 0.1 9.6 5.2 2.8 6.3 3.5 2.5 1.4 3.5 2.4 12.1 4.1 2.5 8.0 3.0 2.8 2.8 0.0 5.9 5.7 4.9 12.6 8.1 14.0 12.8 4.2 3.2 2.6 5.9 7.4 4.3 5.0 7.3 4.8 5.0 9.1 3.2 9.3 1.8 4.9 6.2 10.9 4.1 7.6 3.5 5.2 5.3 4.4 5.1 4.8 12.6 3.6 3.7 3.5 6.1 3.2 3.9 2.6 4.5 9.6 8.5 3.7 6.0 8.2 4.8 5.7 4.8 5.0 5.0 5.2 4.4 7.3 4.0 6.9 3.4 9.6 6.9 6.7 10.0 6.8 8.5 4.2 5.8 4.0 4.0 2.8 2.4 10.7 0.0 6.1 1.9 4.0 8.9 13.7 6.6 4.7 0.1 3.0 0.3 0.2 1.8 35.0 0.5 28.1 0.6 16.9 27.9 0.5 0.6 5.2 19.2 0.6 24.4 0.7 0.3 11.0 10.4 5.9 5.0 37.3 10.1 5.2 2.7 0.1 9.6 1.4 0.0 12.6 5.9 20.5 3.2 14.6 128.9 24.4 8.2 15.5 8.5 27.3 55.7 13.9 11.2 17.9 10.0 8.3 16.5 104.3 10.5 95.5 7.3 7.9 8.0 5.4 18.2 15.7 15.0 9.1 35.4 224.3 7.3 11.8 11.3 16.8 15.8 11.4 47.9 15.0 11.0 4.0 161.5 187.5 9.9 12.2 8.6 7.6 8.8 17.4 9.0 8.8 38.4 11.8 24.9 247.2 200.6 113.6 6.3 9.6 14.3 30.1 12.7 10.6 13.6 8.8 79.8 0.0 25.5 9.0 31.4 26.4 12.8 6.7 3.7 79.4 23.3 11.5 9.5 PTPRB PTPB ENSG00000127329 "Protein tyrosine phosphatase receptor type B" P23467 12 70515870-70637440 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Angiogenesis "Hydrolase, Protein phosphatase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 215.9;Endothelial cells: 211.5;Hepatic stellate cells: 504.0;Microglial cells: 164.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 24.3;hTERT-RPE1: 19.7;HUVEC TERT2: 61.4;TIME: 90.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004782, HPA067868" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA 14000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cell Junctions" "CAB004782: , HPA067868: AB_2685911" "unprognostic (3.18e-1)" "unprognostic (2.99e-6)" "unprognostic (1.56e-1)" "unprognostic (1.80e-1)" "unprognostic (3.55e-2)" "unprognostic (1.77e-2)" "prognostic favorable (6.05e-4)" "unprognostic (4.59e-1)" "unprognostic (2.22e-2)" "unprognostic (1.85e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-1)" "prognostic favorable (1.02e-4)" "unprognostic (2.91e-2)" "unprognostic (7.18e-2)" "unprognostic (1.31e-1)" "unprognostic (1.38e-1)" 26.7 9.4 16.0 4.7 14.1 0.1 18.8 12.3 12.1 12.8 7.1 10.9 7.5 12.3 4.4 6.8 10.8 14.7 23.2 10.1 12.4 22.5 16.7 35.7 3.2 15.9 14.2 4.0 6.2 7.8 4.7 32.6 18.1 6.3 11.1 1.4 3.3 8.0 17.1 4.1 9.3 18.1 12.4 30.0 6.2 2.5 19.0 3.0 14.8 38.8 3.4 7.7 5.3 11.9 4.4 0.3 1.9 0.2 0.0 0.1 0.9 0.9 4.2 2.2 5.2 0.1 3.4 1.7 24.3 0.6 0.4 15.2 0.2 0.7 7.8 1.3 0.7 0.4 1.7 1.1 0.2 0.7 0.0 0.1 0.7 6.1 0.0 19.7 61.4 0.0 3.6 1.0 1.3 0.0 0.1 0.0 2.3 4.4 0.9 0.1 1.6 0.9 11.3 1.8 0.0 0.8 1.6 0.0 3.5 0.4 0.0 1.5 90.3 0.9 0.9 0.4 5.4 1.1 0.9 0.8 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 16.0 14.1 12.3 12.1 10.1 12.4 15.9 14.2 18.1 12.4 19.0 11.9 215.9 0.0 13.2 2.0 3.1 3.7 0.8 1.0 0.0 7.1 0.9 0.9 12.3 11.5 1.3 3.7 0.0 0.0 2.0 12.8 0.0 1.5 4.6 2.2 0.7 211.5 0.0 16.0 52.5 0.9 0.0 7.3 1.5 4.0 25.2 0.5 504.0 4.7 0.4 5.0 68.8 6.4 0.0 20.0 4.6 3.0 1.2 1.2 5.4 164.9 0.0 0.4 0.0 2.5 2.9 12.2 11.1 0.0 0.1 0.8 3.2 0.1 0.2 0.9 0.0 6.4 5.2 0.7 0.7 0.9 1.6 0.0 1.0 1.8 6.8 0.7 PTPRCAP "CD45-AP, LPAP" ENSG00000213402 "Protein tyrosine phosphatase receptor type C associated protein" Q14761 11 67435510-67437682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 79.7;lymphoid tissue: 174.1" "Group enriched" "Detected in some" 6 "B-cells: 203.3;Plasma cells: 283.5;T-cells: 233.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 351.1;HDLM-2: 242.3;HL-60: 140.6;MOLT-4: 206.8;NB-4: 996.9;U-698: 248.9" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Low region specificity" "Detected in many" HPA043734 Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA043734: AB_10962214" 7.1 2.9 3.0 73.0 2.9 27.0 5.3 2.6 4.9 7.0 3.1 14.3 14.0 4.6 0.0 7.9 7.9 3.0 3.5 2.5 2.5 9.9 8.9 14.4 126.5 3.9 2.8 5.0 3.8 0.3 4.2 0.6 3.4 10.6 2.4 0.0 10.2 0.6 2.2 4.2 79.7 0.9 3.4 174.1 24.7 1.5 3.0 109.2 13.0 0.2 51.3 7.5 7.0 3.5 0.4 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.2 351.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 242.3 0.5 0.2 0.9 0.0 0.0 140.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 95.5 1.1 33.3 0.1 3.7 206.8 996.9 0.0 0.0 0.3 65.8 0.2 0.6 0.0 1.1 0.2 0.4 0.2 0.0 1.1 0.0 0.6 0.3 1.4 0.0 1.5 0.0 0.3 0.3 0.3 248.9 0.0 0.3 0.1 23.6 6.7 75.0 1559.9 5.6 1322.2 1334.4 955.3 1380.5 12.7 1714.2 688.5 1083.9 33.4 826.7 8.0 848.7 1374.2 1237.9 3.0 2.9 2.6 4.9 2.5 2.5 3.9 2.8 3.4 3.4 3.0 3.5 0.0 0.0 0.0 7.2 203.3 12.7 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 15.1 0.2 0.0 0.0 4.4 17.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.3 20.6 0.0 0.0 5.0 39.2 7.5 0.5 0.0 1.0 0.5 3.1 0.0 0.0 0.0 283.5 0.0 0.0 0.1 1.4 0.0 0.0 0.0 3.5 0.0 0.0 1.6 9.7 0.0 233.3 0.0 0.0 0.0 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 356.8;Excitatory neurons: 416.1;Inhibitory neurons: 684.3;Microglial cells: 771.0;Oligodendrocyte precursor cells: 920.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 81.7;HSkMC: 61.1" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 18.0 13.2 7.6 4.6 7.8 0.0 12.8 4.9 10.4 11.9 23.4 8.2 3.7 10.6 8.4 4.1 9.0 8.3 10.0 13.7 6.2 14.4 5.8 12.8 1.8 8.4 7.2 12.0 3.9 26.6 5.2 9.9 5.9 7.8 6.1 8.6 5.2 8.4 7.4 4.5 5.9 13.0 10.0 7.0 5.8 7.7 9.1 2.1 13.1 10.4 1.7 7.0 6.7 5.0 0.0 5.3 27.3 0.0 81.7 41.6 13.5 17.6 28.5 18.2 24.4 13.2 0.5 0.6 10.1 20.7 14.5 0.2 13.4 13.6 28.3 1.5 7.7 1.4 0.1 15.0 27.5 7.5 0.1 61.1 5.3 25.9 30.9 5.8 19.7 2.0 0.0 17.3 16.3 7.6 0.0 0.1 17.0 0.1 0.0 11.9 8.6 0.6 18.2 8.2 2.1 4.5 4.3 0.1 6.9 11.2 0.2 0.3 46.0 25.4 24.1 41.0 14.7 5.5 6.8 0.0 19.2 3.2 31.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.6 7.8 4.9 10.4 13.7 6.2 8.4 7.2 5.9 10.0 9.1 5.0 45.3 12.8 32.4 356.8 2.2 9.2 6.4 5.0 13.1 98.5 9.6 6.3 12.5 8.6 5.8 22.0 6.2 10.5 0.9 12.1 5.9 9.6 3.6 14.4 31.9 55.5 24.6 0.0 416.1 1.8 0.8 47.7 4.1 30.5 0.0 64.6 90.3 32.7 19.7 154.8 684.3 8.9 22.4 2.9 8.8 4.3 66.5 1.1 17.8 771.0 0.6 40.8 2.1 920.3 11.8 5.3 5.6 56.8 4.2 10.9 13.9 18.2 2.8 5.7 72.3 81.1 60.6 2.0 8.6 2.1 4.8 12.6 2.3 20.0 12.1 2.7 PTPRK R-PTP-kappa ENSG00000152894 "Protein tyrosine phosphatase receptor type K" Q15262 6 127968785-128520616 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 889.9;Oligodendrocyte precursor cells: 313.1;Oligodendrocytes: 1278.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 1.6;naive B-cell: 2.9" "Lineage enriched" "Detected in single" 7 "B-cells: 2.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054056, HPA054822" Uncertain Supported "Vesicles,Plasma membrane,Cell Junctions" NA NA 13000000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions" "Vesicles, Plasma membrane" "HPA054056: AB_2682359, HPA054822: AB_2682614" "unprognostic (3.15e-2)" "unprognostic (1.07e-2)" "unprognostic (5.79e-3)" "unprognostic (4.95e-3)" "unprognostic (1.89e-2)" "unprognostic (7.26e-2)" "unprognostic (3.27e-1)" "unprognostic (6.06e-2)" "unprognostic (2.04e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (1.99e-4)" "unprognostic (1.46e-1)" "prognostic favorable (9.33e-5)" "unprognostic (2.10e-1)" "unprognostic (1.55e-1)" "unprognostic (2.59e-1)" "unprognostic (9.32e-2)" 10.7 4.2 13.4 9.7 20.6 0.2 25.6 16.7 18.6 13.5 8.6 27.3 32.8 12.1 8.2 9.7 14.9 32.5 12.4 15.9 14.5 14.9 29.6 19.4 6.9 16.8 16.7 15.1 26.2 10.2 7.0 21.8 17.8 18.9 27.6 4.6 15.3 19.0 5.9 12.2 28.5 15.9 14.5 7.9 30.5 2.2 16.4 10.2 11.7 9.9 8.7 20.9 12.3 29.8 17.3 16.7 10.9 1.0 24.9 31.9 11.0 43.6 86.3 18.4 16.6 28.8 15.0 0.1 13.4 40.7 50.8 49.0 10.2 35.9 26.7 50.3 19.4 0.3 23.6 45.7 29.7 0.0 1.7 23.9 35.4 35.9 49.6 50.8 54.0 14.7 0.0 1.1 49.3 33.6 26.6 0.1 11.9 34.5 22.6 94.8 21.7 3.1 51.1 33.4 43.8 0.1 45.2 55.6 2.7 12.4 14.6 1.1 86.9 30.0 18.4 54.8 42.2 0.7 6.0 0.0 38.1 0.0 31.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.9 0.1 0.3 0.0 0.2 0.0 0.0 0.1 0.1 13.4 20.6 16.7 18.6 15.9 14.5 16.8 16.7 17.8 14.5 16.4 29.8 39.2 25.6 33.5 155.7 17.5 63.5 88.1 45.2 60.3 7.3 56.6 26.5 22.2 101.5 44.1 18.4 4.2 24.8 0.8 75.2 0.0 63.2 4.6 30.6 11.5 46.6 43.9 0.0 889.9 61.3 4.1 28.6 77.5 77.5 1.3 13.4 11.4 40.9 6.4 10.1 55.3 44.2 8.2 1.6 8.8 2.7 17.1 2.2 17.8 200.5 1.7 5.1 0.0 313.1 1278.1 124.2 53.8 18.0 1.0 115.8 68.7 13.4 25.9 0.7 59.2 20.1 41.5 11.3 8.9 27.0 38.1 26.8 3.4 14.1 56.6 157.0 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 PTPRR "EC-PTP, PCPTP1, PTP-SL, PTPBR7, PTPRQ" ENSG00000153233 "Protein tyrosine phosphatase receptor type R" Q15256 12 70638073-70920738 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 14.4;endometrium 1: 5.5;intestine: 7.6" "Group enriched" "Detected in some" 4 "Excitatory neurons: 199.5;Inhibitory neurons: 160.7" "Cancer enhanced" "Detected in many" "urothelial cancer: 3.6" "Group enriched" "Detected in many" 5 "amygdala: 3.7;basal ganglia: 5.7;cerebellum: 14.4;cerebral cortex: 6.5;hippocampal formation: 7.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HDLM-2: 20.0;RT4: 37.4" "Region enriched" "Detected in all" 5 "cerebellum: 89.6" "CAB011461, HPA011851, HPA071067" Uncertain Supported "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 45: Intestine - Brush border" "Cluster 15: RT4 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions, Cytosol" "CAB011461: AB_298890, HPA011851: AB_1855939, HPA071067: AB_2686340" "unprognostic (4.98e-2)" "unprognostic (1.91e-2)" "unprognostic (1.55e-1)" "unprognostic (2.04e-1)" "unprognostic (3.63e-3)" "unprognostic (3.48e-5)" "unprognostic (5.44e-3)" "unprognostic (1.77e-3)" "unprognostic (1.13e-1)" "unprognostic (9.01e-2)" "unprognostic (1.37e-3)" "unprognostic (8.06e-2)" "unprognostic (1.10e-2)" "unprognostic (1.92e-2)" "unprognostic (4.78e-2)" "unprognostic (2.72e-1)" "prognostic favorable (1.40e-5)" 0.0 2.2 3.7 1.0 5.7 0.0 0.0 14.4 6.5 0.3 0.0 7.4 3.2 5.5 0.0 0.0 0.1 1.0 0.0 7.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.3 0.2 0.1 0.0 5.0 2.5 0.0 1.1 0.0 0.0 7.6 2.9 1.5 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.4 0.0 0.0 0.7 0.0 0.0 0.0 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 37.4 0.1 5.8 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 5.7 14.4 6.5 7.2 0.5 0.2 0.0 0.1 1.5 0.0 1.5 1.7 0.0 0.0 3.9 0.2 0.5 0.1 0.5 0.0 16.5 0.2 0.1 3.5 0.0 3.4 0.0 0.0 0.0 0.7 43.2 0.0 2.6 1.7 2.2 1.3 4.0 0.0 0.0 199.5 0.2 0.3 0.3 10.2 14.6 0.0 0.0 0.7 0.0 0.0 16.8 160.7 1.8 0.0 0.0 0.3 0.4 0.0 0.2 0.0 3.7 0.0 0.2 1.0 2.0 4.0 2.8 23.0 0.0 0.0 0.4 17.3 0.0 0.1 0.8 0.0 0.1 0.8 0.0 0.1 0.0 0.1 0.8 0.4 0.0 0.7 0.4 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PURG "PURG-A, PURG-B" ENSG00000172733 "Purine rich element binding protein G" Q9UJV8 8 30995802-31033715 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.5;retina: 4.1" "Cell type enhanced" "Detected in some" "Astrocytes: 61.0;Excitatory neurons: 57.2;Inhibitory neurons: 69.5;Late spermatids: 22.0;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 27.8" "Cancer enhanced" "Detected in some" "glioma: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 6.1;JURKAT: 4.3;NTERA-2: 4.8;SH-SY5Y: 5.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047746 Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" Nucleoli "HPA047746: AB_2680145" "unprognostic (3.37e-1)" "unprognostic (2.15e-1)" "unprognostic (6.69e-2)" "unprognostic (7.33e-3)" "unprognostic (3.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.51e-3)" "unprognostic (1.10e-2)" "unprognostic (1.49e-1)" "unprognostic (1.62e-1)" "unprognostic (4.79e-2)" "unprognostic (8.72e-2)" "unprognostic (1.46e-3)" "unprognostic (1.03e-1)" "unprognostic (1.27e-1)" "unprognostic (1.83e-2)" "unprognostic (5.30e-2)" 0.3 0.4 7.7 0.2 8.3 0.0 0.2 10.5 9.0 1.3 0.5 0.3 0.1 2.0 0.6 0.2 0.4 0.8 0.4 8.7 7.7 0.4 0.0 0.2 0.2 6.6 6.7 0.5 0.0 0.0 3.0 0.2 7.4 0.5 0.1 4.1 0.3 0.6 0.1 0.0 0.2 1.3 6.1 0.6 0.2 2.6 7.3 0.1 0.2 0.2 0.1 0.2 0.8 6.5 0.0 0.0 6.1 0.1 0.0 0.0 0.0 0.1 0.3 0.5 1.2 0.0 0.0 0.1 0.0 0.0 2.1 0.0 2.0 0.0 0.7 0.0 3.1 1.1 0.0 0.2 0.0 0.0 0.1 0.9 0.0 0.9 0.0 0.7 3.0 4.3 0.3 0.4 0.1 0.0 0.6 0.0 4.8 0.0 0.2 1.6 0.8 0.0 0.0 0.0 0.8 5.7 0.0 0.0 0.0 2.2 0.0 0.0 1.9 2.0 2.5 0.0 0.3 0.2 0.0 0.1 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 8.3 10.5 9.0 8.7 7.7 6.6 6.7 7.4 6.1 7.3 6.5 0.5 0.0 0.0 61.0 0.0 0.0 0.0 0.0 0.0 13.3 0.1 0.3 0.6 0.0 0.0 0.0 2.1 0.0 0.1 0.1 0.0 0.0 17.3 0.2 3.2 0.5 0.0 0.0 57.2 0.0 0.0 1.1 0.0 0.1 0.0 3.6 0.0 0.0 0.0 20.2 69.5 0.0 0.0 0.0 0.3 22.0 0.6 0.1 0.0 12.2 0.0 10.8 0.0 49.3 27.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 2.1 0.0 0.3 1.3 4.2 1.5 0.0 0.0 0.0 0.1 1.8 0.0 0.0 PVALB D22S749 ENSG00000100362 Parvalbumin P20472 22 36800684-36819479 "Predicted intracellular proteins" "Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "parathyroid gland: 2129.3" "Group enriched" "Detected in some" 7 "Distal tubular cells: 641.8;Horizontal cells: 1527.7" "Cancer enriched" "Detected in many" 4 "renal cancer: 59.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "neutrophil: 4.6" "Lineage enriched" "Detected in single" 5 "granulocytes: 4.6" "Cell line enriched" "Detected in some" 291 "RPMI-8226: 1561.0" "Region enriched" "Detected in all" 5 "cerebellum: 2120.1" "Low region specificity" "Detected in all" "CAB002515, HPA048536" Enhanced Approved "Nucleoplasm,Nucleoli,Cell Junctions" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 62: Horizontal cells - Visual perception" Nucleoplasm "Nucleoli, Cell Junctions" "CAB002515: AB_563948, HPA048536: AB_2680433" "unprognostic (4.41e-2)" "unprognostic (1.60e-1)" "unprognostic (9.75e-2)" "unprognostic (1.79e-3)" "unprognostic (7.80e-2)" "unprognostic (2.49e-2)" "unprognostic (2.52e-2)" "unprognostic (6.53e-2)" "unprognostic (2.37e-1)" "unprognostic (2.24e-1)" "unprognostic (1.61e-1)" "unprognostic (2.13e-1)" "unprognostic (5.21e-2)" "unprognostic (6.92e-2)" "unprognostic (1.91e-1)" "unprognostic (1.65e-2)" "unprognostic (8.99e-3)" 0.4 1.0 82.5 0.7 40.2 0.1 15.0 255.6 86.5 0.1 8.6 0.3 0.2 1.4 0.8 0.1 0.1 0.3 0.2 9.3 100.5 82.1 5.7 2.2 2.4 127.4 85.7 0.5 0.2 2129.3 1.2 2.4 105.7 0.3 0.3 373.5 2.7 0.7 13.6 0.1 0.3 0.5 50.9 3.2 0.8 1.5 275.5 0.3 5.0 0.4 3.1 3.8 0.2 51.8 0.0 0.0 3.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 0.0 0.1 0.4 1561.0 0.0 5.3 2.3 0.0 0.0 1.2 0.0 0.1 0.3 0.0 0.0 0.0 1.2 0.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.1 4.6 0.0 0.0 0.9 0.3 15.1 82.5 40.2 255.6 86.5 9.3 100.5 127.4 85.7 105.7 50.9 275.5 51.8 0.0 0.0 0.0 3.9 0.3 0.0 0.0 0.0 0.0 51.3 2.4 2.0 0.6 0.0 0.0 38.6 10.4 0.3 0.0 0.0 641.8 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.8 0.0 0.3 0.5 0.0 0.0 11.4 0.2 30.0 0.2 53.8 1527.7 29.7 0.0 0.0 2.9 0.0 0.1 0.6 15.7 0.0 2.8 0.1 37.4 0.0 3.0 3.3 0.0 0.0 0.0 0.1 0.0 0.0 2.3 0.0 150.5 0.0 1.0 0.0 0.0 3.6 0.0 0.0 0.4 0.9 0.0 0.0 0.1 PVR "CD155, HVED, Necl-5, NECL5, PVS, Tage4" ENSG00000073008 "PVR cell adhesion molecule" P15151 19 44643798-44666162 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 4.5;intermediate monocyte: 4.5;myeloid DC: 3.8;non-classical monocyte: 5.5" "Group enriched" "Detected in many" 4 "dendritic cells: 3.8;monocytes: 5.5" "Cell line enhanced" "Detected in many" "TIME: 175.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012568, HPA064739" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" "Secreted - unknown location" NA NA 720000000 "Cluster 7: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Nucleoplasm, Vesicles, Plasma membrane" "HPA012568: AB_1846248, HPA064739: " "unprognostic (2.90e-3)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.36e-1)" "unprognostic (2.34e-1)" "unprognostic (7.89e-2)" "unprognostic (2.45e-3)" "unprognostic (3.06e-2)" "prognostic unfavorable (9.30e-4)" "unprognostic (9.05e-3)" "unprognostic (1.69e-1)" "unprognostic (2.09e-3)" "unprognostic (2.64e-3)" "unprognostic (1.69e-1)" "unprognostic (4.97e-1)" "unprognostic (1.27e-1)" "unprognostic (1.04e-3)" "prognostic unfavorable (2.75e-4)" 13.9 17.5 10.2 7.1 9.1 5.1 9.6 9.0 10.0 8.7 9.3 10.3 12.5 13.9 5.2 8.4 11.8 6.2 28.5 9.0 16.6 13.6 30.7 19.4 2.7 9.7 11.0 12.5 14.0 10.3 17.3 12.5 12.4 9.7 8.8 5.4 9.9 6.4 19.0 7.1 11.1 10.5 7.4 4.6 12.3 5.8 14.9 2.5 10.6 6.2 2.8 9.1 8.5 7.9 58.8 52.1 5.6 25.0 8.6 9.7 7.4 96.7 38.8 40.7 45.8 31.9 28.2 0.1 50.6 43.7 60.2 44.4 24.3 51.1 31.7 7.8 27.1 8.8 40.3 23.3 43.7 4.1 22.2 10.6 28.0 40.9 82.5 49.7 50.7 6.6 4.3 0.5 23.4 7.8 4.2 5.8 12.5 30.1 31.7 0.1 23.2 5.0 111.8 25.5 21.2 22.9 66.3 54.3 14.7 7.2 22.8 12.5 175.3 39.0 52.8 33.7 78.2 0.3 6.3 0.2 35.3 23.4 24.6 0.2 4.5 0.0 0.1 4.5 0.0 0.0 0.0 0.2 3.8 0.0 0.2 0.1 1.1 0.7 5.5 0.5 0.0 1.7 10.2 9.1 9.0 10.0 9.0 16.6 9.7 11.0 12.4 7.4 14.9 7.9 11.1 16.0 25.2 2.3 1.6 3.6 16.0 6.9 4.0 5.7 4.7 3.4 14.4 14.3 12.2 1.8 2.1 2.9 0.2 18.5 3.9 37.9 10.5 5.4 6.3 20.4 13.1 2.1 11.4 35.3 34.8 7.7 13.7 11.6 1.3 6.5 7.9 41.1 8.4 1.7 13.7 11.3 2.0 8.9 7.5 14.3 5.6 6.8 1.8 5.6 17.2 1.8 2.1 6.0 4.6 69.6 18.0 15.8 0.2 14.4 10.8 5.7 2.8 3.4 0.0 23.8 10.4 10.4 1.5 5.8 5.5 1.0 0.9 10.8 12.7 7.4 PXDC1 C6orf145 ENSG00000168994 "PX domain containing 1" Q5TGL8 6 3722614-3751713 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.6;Basal prostatic cells: 115.1;Extravillous trophoblasts: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "HHSteC: 151.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019246 Approved "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA019246: AB_2670113" "unprognostic (1.55e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.82e-2)" "unprognostic (3.80e-2)" "unprognostic (2.95e-1)" "unprognostic (1.48e-1)" "unprognostic (6.73e-2)" "unprognostic (6.08e-2)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (6.17e-3)" "unprognostic (1.10e-1)" "unprognostic (2.97e-1)" "unprognostic (2.84e-1)" 68.0 14.9 33.7 14.7 34.6 1.4 50.5 35.1 36.5 30.3 49.3 37.2 29.9 31.4 15.6 25.5 28.3 48.3 36.0 33.0 35.2 25.9 168.7 47.6 13.0 39.5 36.1 19.2 26.7 14.2 13.9 61.8 36.4 29.8 7.7 3.1 39.3 19.8 16.9 38.7 26.5 26.7 36.9 19.0 28.5 5.6 35.7 7.4 44.6 15.6 6.7 46.3 28.7 36.0 44.5 17.5 28.6 19.9 87.9 66.4 99.4 75.6 57.7 62.6 48.2 30.6 8.8 0.0 49.0 123.9 48.0 34.4 5.7 20.8 29.3 43.2 6.6 0.0 14.7 26.8 151.4 0.1 0.2 59.0 67.2 38.8 83.2 52.7 70.2 3.0 0.1 5.9 49.7 2.7 0.1 0.5 1.3 9.0 27.3 2.5 16.0 2.1 24.4 35.7 3.1 1.6 51.7 52.4 115.5 38.3 4.6 2.7 77.8 56.9 24.7 22.2 54.4 0.1 0.1 0.2 13.6 0.1 40.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 33.7 34.6 35.1 36.5 33.0 35.2 39.5 36.1 36.4 36.9 35.7 36.0 103.6 48.1 8.6 8.1 8.1 48.3 115.1 11.8 40.9 0.6 28.0 27.7 8.1 18.6 11.7 7.3 0.0 32.8 1.5 0.6 11.7 33.2 0.5 4.7 18.3 39.6 0.0 5.3 0.1 51.6 131.0 62.1 14.8 5.6 3.8 1.6 45.7 68.7 25.1 0.0 2.6 1.4 8.2 9.7 80.8 0.9 22.7 31.6 24.9 9.4 22.0 16.0 0.0 11.1 2.5 77.6 0.1 18.0 4.4 55.8 25.7 20.4 9.6 0.8 0.0 38.7 33.4 0.6 4.5 17.5 33.1 78.4 3.2 0.4 1.2 47.4 PXK "FLJ20335, Slob" ENSG00000168297 "PX domain containing serine/threonine kinase like" Q7Z7A4 3 58332880-58426127 "Enzymes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "brain: 320.5" "Cell type enriched" "Detected in all" 9 "Oligodendrocytes: 732.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-937: 159.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024068 Supported Supported "Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 32: U-937 - Innate immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane, Centriolar satellite" "HPA024068: AB_1855967" "unprognostic (2.98e-2)" "unprognostic (3.29e-1)" "unprognostic (2.71e-3)" "unprognostic (1.61e-1)" "unprognostic (2.40e-1)" "unprognostic (6.62e-3)" "unprognostic (5.03e-3)" "prognostic favorable (5.68e-4)" "unprognostic (3.90e-1)" "unprognostic (8.09e-2)" "unprognostic (3.48e-2)" "unprognostic (1.21e-1)" "unprognostic (1.38e-3)" "unprognostic (2.14e-1)" "unprognostic (1.06e-1)" "unprognostic (1.03e-1)" "unprognostic (2.86e-2)" 19.9 16.7 71.6 31.5 161.3 73.1 15.8 112.3 109.2 46.7 20.4 23.3 10.6 23.5 8.4 11.3 17.5 15.5 17.8 84.1 115.0 18.2 11.6 20.6 43.0 158.2 131.3 18.3 15.7 21.2 13.4 29.7 154.1 12.8 10.5 35.6 14.8 11.7 18.8 14.3 19.3 18.7 82.1 25.2 16.3 12.4 119.0 13.7 63.1 14.3 44.9 19.5 30.2 320.5 13.7 6.9 6.8 12.0 79.7 70.0 17.8 22.6 42.5 19.7 27.3 4.0 3.1 74.7 5.1 33.6 28.4 4.2 18.7 13.2 21.8 18.5 12.5 13.1 11.3 5.8 87.5 112.8 22.5 57.4 31.6 24.6 42.0 72.5 17.8 49.1 15.7 26.1 35.7 5.3 26.2 122.2 7.8 4.1 19.7 40.7 9.4 13.4 12.6 8.0 6.0 4.0 14.2 11.0 19.0 10.7 34.8 122.9 17.9 24.9 11.0 48.5 23.9 19.4 21.6 73.7 36.2 159.3 10.7 39.5 44.6 69.1 23.8 37.2 20.7 62.6 17.1 20.3 41.8 69.6 15.3 17.5 73.5 21.6 57.1 32.1 21.1 32.0 71.6 161.3 112.3 109.2 84.1 115.0 158.2 131.3 154.1 82.1 119.0 320.5 20.1 9.6 6.3 28.4 59.8 14.1 5.8 5.6 7.4 31.0 5.9 7.1 13.1 7.2 6.0 23.9 20.9 19.7 31.7 8.3 33.2 7.1 69.7 9.1 33.0 14.2 7.8 19.3 33.8 5.7 6.8 41.5 6.1 16.0 19.7 15.2 16.4 7.5 13.6 20.2 53.7 5.0 2.0 24.5 31.1 38.3 30.7 25.2 17.8 30.0 28.6 32.7 30.9 79.4 732.6 3.0 5.5 25.2 17.6 6.0 8.7 12.2 6.4 22.2 19.7 18.7 18.2 16.8 21.9 10.1 13.1 35.2 16.9 18.3 5.0 3.9 PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.2;Hofbauer cells: 177.6;Muller glia cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 279.1;HMC-1: 304.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 110.1 21.0 5.9 24.1 6.6 108.9 36.4 5.0 8.4 33.6 10.4 19.0 3.7 20.7 6.4 55.8 19.1 13.0 14.9 5.2 6.2 10.2 145.6 26.1 6.3 10.7 17.6 18.2 5.7 21.1 7.5 49.3 8.7 13.0 24.0 78.2 26.8 29.7 5.1 37.0 8.4 26.7 8.6 49.4 9.6 5.2 9.0 4.8 10.2 5.8 6.8 41.7 38.1 10.3 145.7 40.8 10.1 64.3 47.0 56.2 114.5 28.6 24.1 77.4 117.3 107.4 18.3 0.1 54.4 171.7 91.2 279.1 107.0 144.8 132.0 0.5 46.8 28.0 60.5 82.4 83.8 106.9 304.4 119.4 56.8 104.1 43.6 75.4 69.3 0.8 11.6 0.5 55.4 144.7 0.4 141.7 39.3 12.8 152.0 2.7 36.2 6.1 104.7 95.1 4.5 4.4 131.0 43.3 1.7 38.6 20.6 200.4 3.2 29.7 49.6 56.0 92.9 1.2 0.3 0.5 27.3 107.7 15.9 50.2 55.9 141.1 0.0 24.2 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 153.7 0.6 15.7 1.2 0.2 24.8 5.9 6.6 5.0 8.4 5.2 6.2 10.7 17.6 8.7 8.6 9.0 10.3 6.7 22.4 6.3 1.3 1.8 30.7 10.5 40.5 6.8 4.6 7.0 3.8 3.4 5.7 35.4 7.3 0.0 28.9 0.2 11.2 3.9 10.9 1.0 35.4 18.9 7.8 1.2 9.0 1.8 2.1 151.2 18.8 6.6 62.6 6.3 9.3 8.2 65.4 177.6 1.7 2.2 7.1 14.2 56.7 7.9 1.5 14.3 54.6 19.6 15.9 52.4 265.1 2.1 14.1 0.6 7.4 5.2 21.8 1.8 9.7 0.0 6.4 24.5 11.9 6.6 15.4 8.8 0.7 1.4 22.4 22.3 21.1 2.3 4.0 14.0 9.2 PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA023689: AB_1855974, HPA074813: " "unprognostic (1.49e-2)" "unprognostic (1.33e-1)" "unprognostic (6.96e-3)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "unprognostic (4.32e-3)" "prognostic unfavorable (3.88e-6)" "unprognostic (2.45e-1)" "unprognostic (2.07e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-1)" "unprognostic (7.40e-3)" "unprognostic (1.63e-2)" "unprognostic (2.81e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.76e-4)" 14.6 30.6 30.0 16.7 30.3 6.5 15.3 29.3 29.8 21.4 21.1 23.5 19.0 19.1 23.5 24.2 20.3 12.7 15.5 29.9 34.0 24.7 20.1 15.7 26.5 30.5 30.8 27.2 18.1 27.5 32.4 16.3 29.1 23.5 15.3 12.7 23.2 23.3 18.9 22.4 24.4 15.7 29.8 28.2 21.6 16.1 35.3 22.5 26.2 15.9 27.8 21.2 20.0 32.3 28.1 19.4 40.4 36.0 39.8 19.5 37.0 17.1 23.0 26.5 22.7 26.1 34.2 34.9 26.4 19.9 28.7 37.2 35.6 23.7 17.4 34.7 25.1 27.9 32.7 23.6 18.5 25.8 23.9 16.2 33.8 23.9 20.0 30.0 16.5 52.5 37.1 57.6 25.2 42.8 36.0 30.0 43.3 55.7 34.2 40.2 25.7 55.6 27.1 26.1 48.4 71.8 27.0 48.5 34.9 39.1 59.7 45.9 14.1 23.5 35.1 25.6 25.1 56.8 54.3 37.1 19.6 32.4 31.8 2.3 3.9 10.9 8.0 6.5 10.0 6.9 10.3 10.7 4.1 7.5 11.0 8.7 3.8 6.3 8.4 3.9 5.8 6.2 30.0 30.3 29.3 29.8 29.9 34.0 30.5 30.8 29.1 29.8 35.3 32.3 7.0 9.6 4.9 5.5 12.6 5.5 3.8 5.8 7.4 11.8 14.3 10.0 5.3 5.7 7.4 12.9 2.1 15.5 14.1 10.3 19.6 6.2 3.4 5.7 7.5 6.8 5.4 12.4 6.3 5.9 12.6 5.8 9.7 7.4 0.0 9.3 7.1 9.4 6.5 21.9 4.3 10.6 6.1 6.6 3.5 2.2 9.0 5.6 5.4 6.5 6.4 10.6 8.2 5.5 4.7 9.7 9.1 9.1 11.5 4.9 12.0 9.8 4.0 6.0 6.6 5.4 6.9 5.9 12.2 9.8 5.3 11.6 11.7 9.3 8.4 3.7 PYM1 "PYM, WIBG" ENSG00000170473 "PYM homolog 1, exon junction complex associated factor" Q9BRP8 12 55901413-55932618 "Predicted intracellular proteins" "Nonsense-mediated mRNA decay, Translation regulation" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 110.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012803, HPA039717, HPA046200" Supported Supported "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" No No 27000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 43: THP-1 - Innate immune response" "Cluster 39: Non-specific - Basic cellular processes" "Nucleoplasm, Nucleoli, Cytosol" "Cell Junctions" "CAB012803: AB_2269494, HPA039717: AB_2676644, HPA046200: AB_10965556" "unprognostic (3.03e-2)" "unprognostic (1.00e-1)" "unprognostic (5.65e-2)" "unprognostic (8.82e-2)" "unprognostic (1.97e-1)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.05e-4)" "unprognostic (3.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.44e-2)" "unprognostic (3.94e-2)" "unprognostic (1.29e-1)" "unprognostic (1.32e-2)" "unprognostic (1.59e-2)" "unprognostic (2.22e-1)" "unprognostic (1.29e-1)" "prognostic favorable (1.34e-4)" 24.5 30.8 19.8 24.0 20.2 22.5 27.9 21.5 24.8 26.1 22.9 31.1 31.6 22.1 41.5 72.3 22.7 19.8 21.8 19.5 20.7 26.3 43.0 20.8 35.4 20.5 20.6 17.1 28.0 26.3 22.3 22.8 20.5 31.2 30.0 17.4 34.0 15.9 29.8 41.9 29.5 19.8 20.1 31.1 24.1 25.9 20.1 33.2 27.0 29.0 42.1 24.8 31.4 20.2 50.3 39.1 56.1 31.4 33.4 43.2 92.6 36.1 43.1 33.3 28.0 57.7 57.9 62.9 53.6 35.1 15.4 38.6 43.6 77.1 26.7 48.6 32.7 51.0 35.1 71.8 40.7 59.7 44.7 39.2 48.8 37.7 56.0 42.2 35.9 27.3 44.5 67.4 39.7 75.3 38.6 105.7 98.3 56.7 20.2 34.3 22.3 72.5 69.5 69.8 37.7 43.4 46.2 61.1 33.1 51.8 74.5 124.0 28.2 20.0 28.3 31.5 26.6 35.5 58.2 97.2 34.2 40.9 31.9 17.5 79.8 75.8 58.5 92.2 72.3 98.1 105.4 82.2 120.2 88.2 68.7 69.5 19.1 53.1 66.5 65.6 186.0 87.2 19.8 20.2 21.5 24.8 19.5 20.7 20.5 20.6 20.5 20.1 20.1 20.2 16.2 19.2 17.3 0.0 28.6 0.0 29.4 0.0 21.1 12.7 41.7 38.4 0.0 25.8 14.2 23.9 8.4 84.3 21.1 29.8 78.2 40.6 15.2 21.1 17.0 16.3 7.3 32.2 0.0 50.6 76.3 17.6 22.4 21.1 18.9 14.5 22.9 44.3 55.2 6.7 0.0 32.1 0.0 47.7 0.0 11.7 23.3 42.8 0.0 0.0 110.4 55.7 48.4 0.0 0.0 54.1 33.7 23.7 21.9 34.7 66.8 61.3 16.8 13.6 13.1 18.0 15.7 23.8 25.6 63.1 0.0 62.0 29.6 16.5 29.3 34.3 RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 846.1" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" 151.4 132.8 78.8 91.0 80.1 104.3 124.1 79.4 112.4 114.1 89.2 123.6 54.1 92.2 111.3 102.0 96.0 83.3 90.1 77.3 88.6 164.6 111.1 116.8 42.5 92.5 85.3 111.1 115.1 97.9 35.4 64.3 89.7 123.5 73.6 10.5 96.3 73.5 45.9 92.1 79.0 67.5 84.7 97.5 123.3 61.7 84.0 19.2 112.8 49.5 47.7 123.2 107.7 83.7 133.4 162.5 143.7 152.8 478.2 846.1 43.2 157.9 381.1 142.6 144.6 165.4 111.9 0.1 230.7 194.4 72.7 88.4 86.9 146.7 198.0 78.6 62.3 110.1 100.5 94.3 199.5 0.4 70.9 620.1 125.3 246.6 109.1 401.0 253.4 0.0 20.6 0.5 246.6 280.0 0.5 55.4 231.8 183.9 151.2 28.9 186.1 0.1 327.0 140.5 7.2 112.6 208.7 179.8 337.0 215.4 294.2 87.0 469.6 256.0 149.5 161.1 174.7 0.4 0.1 0.9 399.6 17.4 399.7 0.0 7.0 0.1 0.0 1.0 0.1 0.7 0.1 0.0 10.5 0.6 0.1 0.4 0.8 0.0 0.1 12.9 0.0 1.9 78.8 80.1 79.4 112.4 77.3 88.6 92.5 85.3 89.7 84.7 84.0 83.7 230.1 41.7 83.4 1.0 9.0 92.0 181.3 196.3 110.4 1.2 126.9 149.2 75.2 120.1 105.3 108.5 2.1 116.3 2.8 81.5 135.0 234.4 119.9 91.9 163.2 239.8 89.1 116.4 0.0 149.2 181.2 100.8 76.5 111.4 40.6 111.9 192.4 136.2 249.1 0.0 0.0 184.2 83.4 111.1 104.5 232.1 106.2 116.0 99.6 7.5 247.4 71.5 2.1 0.0 0.1 158.1 110.6 124.1 10.6 197.0 135.7 206.5 72.2 3.8 151.2 46.9 151.4 103.6 18.4 124.8 98.2 92.9 8.9 141.6 146.1 195.9 RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 22.3;Peritubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC TERT1: 97.2;U-2197: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA029135: AB_10602070, HPA029136: AB_10601794" "unprognostic (8.78e-2)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.55e-2)" "unprognostic (5.33e-3)" "unprognostic (6.41e-2)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "unprognostic (9.12e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-3)" 9.6 6.1 8.6 13.2 9.0 0.8 7.8 10.9 9.6 45.9 6.1 59.7 7.0 52.6 14.1 19.9 14.5 26.9 12.3 8.5 15.2 7.3 4.1 10.6 4.5 8.7 8.7 10.8 2.9 5.7 3.4 27.6 9.5 38.7 15.9 3.9 3.9 55.7 6.1 4.8 10.8 75.0 9.2 2.2 11.6 5.1 9.7 3.2 32.6 10.4 4.1 46.7 14.7 11.5 15.6 6.1 21.6 15.3 32.3 97.2 19.8 44.9 77.4 38.6 39.7 13.4 7.3 3.1 13.6 72.3 19.3 5.5 22.7 16.4 45.6 11.6 10.5 11.3 9.4 10.6 19.8 5.9 1.6 36.5 18.6 48.1 44.7 18.7 20.3 6.6 17.6 9.3 43.4 13.2 5.2 6.3 8.1 10.3 8.2 5.7 31.7 4.7 26.8 10.7 11.2 7.6 22.5 10.6 11.6 26.8 9.7 6.8 27.4 59.6 18.5 177.4 26.6 8.0 9.3 7.6 33.5 12.5 30.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.0 8.6 9.0 10.9 9.6 8.5 15.2 8.7 8.7 9.5 9.2 9.7 11.5 2.9 12.8 5.0 6.8 0.7 4.1 1.6 2.0 5.7 2.5 4.0 3.0 3.4 1.5 1.6 0.0 2.1 11.5 1.7 2.4 0.0 3.4 2.4 6.5 15.5 2.6 1.2 4.8 13.0 2.9 10.7 22.3 1.1 6.2 0.0 3.7 4.6 3.4 4.2 1.7 12.3 1.4 2.0 0.8 3.1 2.5 19.9 1.4 5.4 11.2 7.7 4.4 0.0 8.0 5.3 2.6 0.1 30.5 0.5 3.5 0.6 6.1 5.3 0.9 0.0 17.2 14.5 6.6 7.8 4.1 5.1 13.7 0.8 4.0 1.6 1.8 RAB25 CATX-8 ENSG00000132698 "RAB25, member RAS oncogene family" P57735 1 156061160-156070504 "Cancer-related genes, Predicted intracellular proteins" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 423.3;skin 1: 210.0" "Cell type enhanced" "Detected in many" "Paneth cells: 249.6;Squamous epithelial cells: 300.6;Undifferentiated cells: 244.6;Urothelial cells: 232.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 1.3" "Lineage enriched" "Detected in single" 13 "T-cells: 1.3" "Cell line enhanced" "Detected in some" "BEWO: 120.9;CAPAN-2: 119.9;MCF7: 171.5;OE19: 392.3;RT4: 153.4;SK-BR-3: 243.3;T-47d: 227.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA010872, CAB033645" Enhanced Uncertain "Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Cell Junctions, Cytosol" "CAB033645: AB_1128883, HPA010872: AB_1079729" "unprognostic (2.43e-1)" "unprognostic (4.57e-1)" "unprognostic (2.24e-1)" "unprognostic (1.71e-1)" "unprognostic (2.64e-1)" "unprognostic (1.97e-1)" "unprognostic (4.27e-2)" "unprognostic (4.63e-2)" "unprognostic (2.82e-1)" "unprognostic (2.03e-2)" "unprognostic (1.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (1.38e-6)" "unprognostic (2.31e-2)" "unprognostic (3.24e-2)" "unprognostic (3.14e-2)" "unprognostic (4.94e-2)" 0.6 0.1 0.1 10.2 0.1 0.1 52.0 0.3 0.3 76.2 0.0 86.2 72.9 7.3 37.5 423.3 47.5 26.4 0.1 0.0 0.0 41.6 1.7 39.2 0.4 0.1 0.1 0.4 57.1 68.9 27.5 12.4 0.1 36.3 78.1 0.0 105.3 28.4 0.9 210.0 65.6 3.7 0.2 0.2 80.9 0.3 0.1 10.1 50.6 0.0 44.0 69.9 148.2 0.3 93.3 0.0 0.0 0.0 0.0 0.0 120.9 0.0 0.0 0.0 0.0 90.4 119.9 0.0 0.1 0.0 0.0 109.5 0.0 51.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 105.8 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 171.5 0.0 0.4 4.8 392.3 0.0 0.1 0.0 0.3 0.0 153.4 13.3 0.0 0.0 243.3 0.3 21.1 227.9 0.4 0.0 0.2 0.2 0.0 0.2 0.0 1.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 1.0 0.2 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.3 0.3 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 1.2 28.9 41.0 0.0 1.5 55.1 102.9 113.9 74.0 0.0 121.4 137.7 0.1 94.4 98.7 86.5 0.0 102.1 2.3 197.8 166.3 170.4 0.0 58.6 6.4 2.6 85.4 0.0 0.1 150.3 30.0 2.3 96.4 66.2 5.7 0.0 0.0 0.4 7.3 0.0 0.1 208.5 89.5 0.0 5.8 0.0 0.3 2.1 21.4 0.0 3.6 0.0 0.0 0.0 0.1 197.3 249.6 0.0 0.3 114.0 195.9 35.5 66.3 0.0 0.0 0.0 6.8 0.2 1.1 300.6 154.7 80.3 2.7 0.0 244.6 232.3 RAB26 ENSG00000167964 "RAB26, member RAS oncogene family" Q9ULW5 16 2140803-2154165 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 84.9;choroid plexus: 43.0;liver: 45.9;pancreas: 42.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 36.1;Enteroendocrine cells: 99.4;Excitatory neurons: 52.0;Inhibitory neurons: 28.3;Intestinal goblet cells: 41.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 20.1;HeLa: 23.2;MCF7: 13.5;SCLC-21H: 27.2;SK-BR-3: 24.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075624 Uncertain "Vesicles,Plasma membrane,Centrosome" "Intracellular and membrane" No No "Cluster 22: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Vesicles, Plasma membrane" Centrosome "HPA075624: " "unprognostic (1.01e-2)" "prognostic favorable (8.20e-5)" "unprognostic (7.25e-2)" "unprognostic (1.52e-1)" "unprognostic (7.34e-2)" "unprognostic (9.41e-3)" "unprognostic (2.81e-2)" "unprognostic (5.10e-2)" "unprognostic (1.82e-2)" "unprognostic (3.55e-2)" "unprognostic (3.75e-2)" "unprognostic (2.14e-1)" "unprognostic (6.48e-2)" "unprognostic (5.68e-2)" "unprognostic (1.23e-1)" "unprognostic (7.16e-2)" "unprognostic (2.92e-3)" 0.3 1.1 53.5 0.1 55.8 0.2 0.9 57.7 84.9 1.7 43.0 5.7 5.6 0.2 1.8 1.6 0.6 0.8 1.8 60.7 46.2 1.4 45.9 0.3 0.3 48.0 45.4 0.2 42.7 3.4 34.0 0.0 49.1 4.9 5.1 6.8 18.4 0.8 1.1 1.5 6.4 0.1 44.0 0.7 13.7 1.0 47.6 0.3 1.7 2.1 0.8 0.8 0.7 51.9 1.7 20.1 0.1 5.1 0.3 0.1 0.1 0.9 1.6 0.7 1.3 0.6 4.0 0.3 1.4 1.3 0.6 3.2 1.1 0.4 0.1 2.2 2.1 0.8 23.2 1.8 0.8 0.0 0.6 0.8 0.2 0.2 0.3 4.6 0.4 3.2 0.4 0.0 2.3 13.5 0.1 1.0 1.2 6.5 1.8 1.7 1.6 3.5 7.7 1.4 27.2 5.4 0.6 24.9 1.0 0.3 8.2 0.3 0.9 0.0 3.5 0.4 0.4 2.9 0.1 0.3 0.5 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 53.5 55.8 57.7 84.9 60.7 46.2 48.0 45.4 49.1 44.0 47.6 51.9 0.2 0.0 1.1 6.5 1.3 1.3 1.6 1.4 8.0 36.1 1.4 1.4 1.6 1.5 3.4 0.0 4.2 0.0 0.0 2.6 0.0 0.4 0.1 1.0 0.3 0.4 99.4 0.0 52.0 1.0 0.0 0.4 12.8 0.4 0.0 0.5 1.1 8.1 0.2 1.7 28.3 41.9 4.1 0.3 0.0 0.1 0.0 0.1 3.6 8.4 0.0 10.7 0.0 20.1 3.6 0.5 1.8 0.0 3.8 1.5 10.5 0.6 2.3 9.1 0.0 0.3 0.3 0.0 2.4 1.5 0.1 0.1 0.2 0.3 3.2 2.6 RAB27B ENSG00000041353 "RAB27B, member RAS oncogene family" O00194 18 54717860-54895516 "Enzymes, Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 44.1" "Cell type enhanced" "Detected in many" "Early spermatids: 259.3;Gastric mucus-secreting cells: 178.4;granulocytes: 246.6;Late spermatids: 209.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.2;NK-cell: 2.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEL: 63.3;hTCEpi: 46.6;hTERT-HME1: 56.0;U-87 MG: 165.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017712, HPA019849" Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA 6500000 "Cluster 48: NK-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 51: Myeloid cells - Hemostasis" "Golgi apparatus, Plasma membrane" Cytosol "CAB017712: , HPA019849: AB_1856000" "unprognostic (1.59e-1)" "unprognostic (5.20e-2)" "unprognostic (9.89e-3)" "unprognostic (7.51e-2)" "unprognostic (8.89e-2)" "unprognostic (1.84e-2)" "unprognostic (1.52e-1)" "unprognostic (2.73e-3)" "unprognostic (6.82e-2)" "unprognostic (8.12e-2)" "prognostic unfavorable (2.13e-4)" "unprognostic (1.39e-2)" "unprognostic (1.20e-3)" "unprognostic (1.42e-1)" "unprognostic (1.84e-2)" "unprognostic (5.75e-1)" "unprognostic (1.29e-1)" 0.3 2.6 7.9 1.1 10.2 1.0 11.9 0.0 11.9 3.0 0.0 4.9 5.1 0.8 0.4 14.0 1.1 3.8 0.1 13.3 5.2 0.3 1.3 7.2 0.5 0.0 0.1 0.2 4.1 2.3 1.0 1.1 0.6 20.5 5.3 1.0 14.0 1.0 0.2 15.6 4.9 0.9 0.1 1.7 44.1 4.5 2.6 1.4 0.3 0.5 5.2 6.2 5.2 3.3 7.8 22.4 0.8 0.0 1.5 19.3 0.0 1.7 13.5 1.8 1.3 0.0 8.6 1.3 0.1 3.9 16.7 14.5 0.2 9.0 0.5 0.0 0.5 63.3 5.0 0.0 2.6 3.4 7.0 15.3 46.6 25.5 56.0 21.1 1.2 0.3 0.0 3.9 16.1 7.9 0.2 7.4 0.2 14.0 14.7 0.0 0.0 0.3 4.1 28.9 0.2 10.3 2.2 13.4 0.0 0.1 8.3 0.3 0.3 18.8 0.6 9.8 2.0 0.4 0.0 0.0 165.2 35.6 0.9 0.6 0.0 0.1 2.2 0.0 0.5 0.0 0.7 1.1 0.0 0.0 0.2 1.0 0.2 2.6 0.0 0.0 0.0 1.6 7.9 10.2 0.0 11.9 13.3 5.2 0.0 0.1 0.6 0.1 2.6 3.3 0.3 48.1 37.6 3.3 0.9 25.6 8.6 18.2 8.0 2.4 59.8 25.3 0.5 8.6 36.9 5.5 2.1 6.5 15.0 5.7 1.9 7.2 259.3 30.9 4.4 1.9 4.2 3.4 101.0 41.0 4.5 2.0 178.4 64.0 246.6 0.4 2.5 0.9 0.6 6.7 75.8 31.3 20.3 0.6 2.7 209.9 2.1 38.1 7.2 2.8 2.1 1.4 29.9 98.5 2.6 34.0 18.6 0.4 3.2 78.9 3.0 0.0 15.8 0.4 6.6 0.3 2.2 7.9 1.4 79.2 49.2 2.9 13.9 0.5 7.9 42.2 RAB3B ENSG00000169213 "RAB3B, member RAS oncogene family" P20337 1 51907956-51990700 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 31.0;pituitary gland: 10.6;prostate: 11.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 147.4;Alveolar cells type 2: 103.2;Enteroendocrine cells: 293.8;Pancreatic endocrine cells: 92.8" "Group enriched" "Detected in many" 6 "prostate cancer: 19.4;testis cancer: 6.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 125.8;BJ hTERT+: 48.4;fHDF/TERT166: 45.8;TIME: 97.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003159, CAB023293" Enhanced Approved "Cell Junctions" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Cell Junctions" "CAB023293: , HPA003159: AB_1856005" "unprognostic (1.10e-1)" "unprognostic (2.20e-3)" "unprognostic (5.43e-3)" "unprognostic (1.65e-2)" "unprognostic (1.82e-1)" "unprognostic (1.38e-2)" "unprognostic (1.20e-2)" "unprognostic (8.77e-3)" "unprognostic (2.79e-1)" "unprognostic (2.81e-1)" "unprognostic (2.42e-2)" "unprognostic (1.06e-1)" "unprognostic (1.03e-2)" "unprognostic (2.02e-3)" "unprognostic (1.06e-1)" "unprognostic (1.05e-1)" "unprognostic (1.15e-2)" 0.0 3.0 11.3 0.6 8.6 0.2 0.7 2.9 14.9 0.0 0.0 1.6 0.7 0.1 0.2 0.0 0.2 1.3 0.0 10.9 23.0 0.5 0.7 0.0 0.1 11.4 17.5 1.5 1.0 0.0 10.6 1.6 31.0 11.0 2.3 1.7 0.2 0.1 0.5 1.9 0.9 0.3 2.3 0.1 1.2 0.3 19.5 0.2 0.0 0.0 0.1 0.1 0.1 3.4 1.8 8.5 1.2 1.3 0.2 2.3 0.2 125.8 48.4 24.8 12.0 10.4 3.7 0.6 2.0 45.8 3.6 0.1 15.4 13.0 41.7 0.0 1.1 0.1 0.6 3.4 2.1 0.0 0.1 1.1 0.4 41.1 9.4 15.4 7.8 1.1 0.4 0.4 27.9 0.3 0.1 0.1 19.9 2.4 1.2 0.3 0.2 0.2 4.0 0.8 4.3 1.1 0.1 0.3 0.1 24.6 0.2 0.3 97.9 24.0 8.8 0.5 41.5 0.2 0.6 0.4 21.9 0.1 1.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 11.3 8.6 2.9 14.9 10.9 23.0 11.4 17.5 31.0 2.3 19.5 3.4 1.4 147.4 103.2 0.3 1.1 2.4 6.2 0.3 0.0 5.0 2.2 3.4 0.7 12.8 27.9 0.0 2.1 0.5 0.4 2.0 3.9 4.0 2.4 1.5 1.3 8.2 293.8 0.0 6.6 18.4 0.3 13.9 3.6 1.4 7.6 27.9 0.7 2.7 0.3 0.0 48.1 14.7 14.2 1.3 1.2 1.3 0.6 3.7 1.8 1.0 1.0 31.2 1.0 1.5 1.5 92.8 1.4 1.2 2.3 18.8 1.4 0.2 29.5 3.7 0.0 4.1 4.8 10.4 4.3 0.0 1.4 4.0 3.3 1.1 1.6 2.7 RAB3GAP2 "DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69" ENSG00000118873 "RAB3 GTPase activating non-catalytic protein subunit 2" Q9H2M9 1 220148293-220272453 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cataract, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026273, HPA027299" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA026273: AB_1856007, HPA027299: AB_1856008" "prognostic unfavorable (3.05e-4)" "unprognostic (2.80e-3)" "unprognostic (1.76e-2)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (7.00e-2)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (2.13e-1)" "unprognostic (7.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" 10.1 9.0 6.3 9.6 6.7 10.2 11.2 11.4 7.8 8.7 23.5 8.8 7.8 9.4 8.4 9.0 7.0 7.9 9.3 7.3 9.3 11.7 10.0 8.6 12.6 6.7 6.9 9.6 8.6 18.6 6.2 11.5 9.0 8.5 8.3 18.1 9.2 7.9 8.7 7.9 7.8 9.3 5.7 9.2 9.4 6.6 7.5 13.1 12.8 12.2 14.4 9.1 6.0 9.1 21.3 15.8 18.9 14.3 21.2 25.1 21.4 21.4 20.3 18.9 22.2 14.7 17.3 26.4 14.8 20.9 14.3 19.9 19.8 16.4 21.8 22.1 12.9 20.6 21.5 13.8 27.9 29.8 20.3 20.0 18.4 18.5 28.5 21.2 17.6 11.4 36.2 16.6 21.6 6.0 23.0 10.5 40.8 11.4 9.3 12.5 26.0 23.7 16.1 17.3 18.8 22.7 22.2 21.4 35.3 20.3 22.4 28.0 25.7 20.6 9.6 14.4 23.2 14.6 19.2 22.8 17.7 24.6 24.8 10.0 2.8 5.6 4.8 3.6 5.9 4.8 4.7 6.2 3.8 3.8 4.1 4.9 1.8 2.8 3.9 2.4 6.0 3.3 6.3 6.7 11.4 7.8 7.3 9.3 6.7 6.9 9.0 5.7 7.5 9.1 28.5 41.7 21.9 60.7 30.4 11.6 13.6 15.8 17.6 57.9 18.9 16.3 34.8 32.9 23.4 25.8 68.8 18.5 30.6 23.8 5.9 17.4 4.3 21.4 27.7 22.3 35.4 18.7 106.8 16.7 13.5 23.4 20.4 28.5 19.6 40.8 28.9 24.2 25.4 42.1 105.1 22.1 16.2 29.0 9.4 2.8 18.0 22.2 14.2 68.4 25.2 39.8 26.8 82.0 81.5 21.7 14.2 25.9 24.7 21.0 19.4 14.9 17.2 50.5 6.6 24.1 20.4 17.7 13.6 17.5 9.8 23.1 27.1 23.6 19.3 13.2 RAB41 ENSG00000147127 "RAB41, member RAS oncogene family" Q5JT25 X 70282093-70285002 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "retina: 65.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 533.8" "Cancer enhanced" "Detected in some" "glioma: 2.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2197: 3.7;U-87 MG: 4.6" "HPA001510, HPA065289" Uncertain Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Vesicles, Plasma membrane" "HPA001510: AB_1079733, HPA065289: " "unprognostic (1.32e-1)" "unprognostic (1.39e-1)" "unprognostic (3.36e-3)" "unprognostic (4.25e-3)" "unprognostic (1.18e-1)" "unprognostic (3.46e-2)" "unprognostic (6.33e-3)" "unprognostic (1.85e-3)" "unprognostic (1.38e-1)" "unprognostic (2.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.04e-3)" "unprognostic (7.63e-2)" "unprognostic (2.39e-1)" "unprognostic (9.78e-3)" "unprognostic (8.42e-2)" "unprognostic (9.89e-2)" 0.2 0.8 0.5 0.5 0.6 0.4 0.1 0.3 0.9 0.1 0.0 0.3 0.4 0.2 0.0 0.3 0.2 0.5 0.6 0.3 0.4 0.3 0.1 0.3 0.5 0.5 0.5 0.8 0.1 0.0 0.2 0.2 0.4 0.2 0.0 65.5 1.0 0.0 0.5 1.3 0.7 0.0 0.4 0.5 0.2 4.0 1.0 0.0 0.8 0.0 0.0 0.3 0.1 0.5 0.5 0.5 1.3 0.5 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.6 0.5 0.6 1.1 0.0 1.1 0.6 0.0 0.0 0.0 0.8 1.3 0.1 1.4 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 1.7 0.0 0.8 0.5 1.2 0.0 0.3 0.8 0.5 0.8 1.7 1.7 0.3 0.9 0.9 0.0 0.4 0.8 1.5 0.5 0.3 1.5 0.6 0.3 1.4 1.6 0.6 0.7 3.7 0.8 0.7 1.1 0.8 4.6 1.1 1.1 0.0 0.0 0.0 0.1 0.2 0.3 0.2 0.1 0.1 0.3 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.6 0.3 0.9 0.3 0.4 0.5 0.5 0.4 0.4 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.3 0.0 0.0 0.0 533.8 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.6 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 28.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RAB43 "ISY1, RAB11B, RAB41" ENSG00000172780 "RAB43, member RAS oncogene family" Q86YS6 3 129087569-129122801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.0;Gastric mucus-secreting cells: 5.6;Plasma cells: 9.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.2" "Group enriched" "Detected in many" 5 "granulocytes: 11.2;T-cells: 2.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046840, HPA060085" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA046840: , HPA060085: AB_2684199" "unprognostic (3.01e-1)" "unprognostic (1.14e-2)" "unprognostic (3.08e-1)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.36e-2)" "unprognostic (3.17e-2)" "unprognostic (4.16e-1)" "unprognostic (8.68e-2)" "unprognostic (3.14e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.82e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" 7.6 8.3 9.5 10.4 9.7 22.3 7.1 11.6 8.1 7.3 9.3 7.9 8.0 6.6 2.9 5.9 7.3 9.4 4.2 7.9 5.8 10.4 46.9 14.8 17.4 10.0 7.5 9.9 10.3 5.2 6.7 3.9 8.4 9.9 2.6 0.7 10.2 5.0 1.8 4.0 6.9 2.7 7.3 10.9 8.1 7.5 7.1 12.9 22.7 1.4 4.6 7.3 4.0 6.7 22.4 6.0 1.4 5.7 2.7 1.2 8.3 7.6 5.1 4.4 3.5 9.4 9.4 0.6 17.1 5.7 5.9 9.2 0.5 8.8 1.0 11.2 5.6 1.5 1.1 12.5 25.9 5.1 12.7 7.1 5.4 2.2 0.5 1.9 8.7 13.0 2.5 10.8 6.1 9.7 5.0 9.8 7.0 5.2 10.5 10.8 3.2 6.6 14.1 18.7 0.4 2.7 3.3 7.0 14.4 2.2 3.0 5.3 12.5 9.3 6.4 7.6 2.9 16.9 9.8 3.6 8.5 1.0 10.3 0.4 1.2 2.3 1.5 1.5 0.7 0.5 1.5 1.2 0.6 1.0 2.8 2.4 11.2 1.4 0.7 0.9 2.4 1.0 9.5 9.7 11.6 8.1 7.9 5.8 10.0 7.5 8.4 7.3 7.1 6.7 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 12.0 0.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.1 0.5 5.6 0.5 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 9.2 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 2.5 0.1 0.1 1.2 0.2 0.3 0.1 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Plasma membrane" No No 4800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favorable (1.71e-4)" "unprognostic (9.99e-2)" 21.3 24.5 17.4 40.4 17.5 61.3 18.7 19.5 17.6 24.6 20.7 37.4 58.5 18.5 18.9 25.9 27.8 22.0 11.5 17.2 19.1 20.8 51.5 28.6 44.3 21.1 19.5 21.5 23.4 17.7 15.3 25.0 21.6 21.7 32.8 8.7 30.7 21.2 7.0 27.5 58.7 22.8 20.3 40.4 32.4 15.4 19.0 34.3 16.3 8.1 45.1 25.9 21.2 23.3 94.2 62.6 50.5 43.0 42.7 36.7 77.9 56.0 48.8 74.2 76.8 76.1 105.7 66.1 61.9 58.6 63.5 60.6 71.2 69.1 50.9 132.6 39.9 135.9 57.1 75.6 46.7 119.4 129.3 36.6 37.6 69.5 32.1 38.9 63.5 65.0 64.4 97.0 63.4 111.6 100.1 113.7 63.3 114.3 100.5 111.6 56.2 115.6 58.2 71.9 46.9 45.3 56.6 68.0 35.9 34.2 53.8 44.2 61.7 61.4 39.2 119.2 96.6 51.4 113.4 97.3 58.7 121.5 67.0 244.5 278.6 315.0 164.3 387.5 145.7 190.5 143.3 147.5 247.5 190.0 112.5 131.7 292.2 225.9 485.1 177.8 150.9 514.1 17.4 17.5 19.5 17.6 17.2 19.1 21.1 19.5 21.6 20.3 19.0 23.3 47.2 25.6 29.1 2.3 70.2 47.7 47.4 53.5 31.3 15.2 37.0 34.7 3.0 17.2 35.7 31.3 14.6 95.7 97.9 115.9 82.2 70.7 31.0 33.7 29.7 37.3 30.4 47.5 4.2 51.5 98.6 36.3 29.6 45.0 48.7 36.2 26.0 50.3 88.9 6.7 3.5 55.3 48.8 50.6 81.5 19.0 27.7 100.9 33.8 2.8 124.8 34.9 131.8 3.0 8.8 76.8 90.0 24.8 96.5 30.7 130.7 62.6 35.4 13.9 32.9 22.0 38.1 33.3 23.4 30.4 52.6 79.6 64.8 43.4 52.0 38.4 RABEPK "bA65N13.1, RAB9P40" ENSG00000136933 "Rab9 effector protein with kelch motifs" Q7Z6M1 9 125200542-125234161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023920, HPA067106" Supported Uncertain "Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA023920: AB_1856023, HPA067106: " "unprognostic (8.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.76e-2)" "unprognostic (1.58e-1)" "unprognostic (3.24e-2)" "unprognostic (2.70e-2)" "unprognostic (3.47e-2)" "unprognostic (3.47e-2)" "unprognostic (9.74e-2)" "unprognostic (4.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (8.25e-2)" "unprognostic (2.69e-1)" 17.4 15.0 27.9 14.6 30.0 11.6 16.4 27.3 32.5 16.4 25.5 17.7 11.5 15.1 16.9 16.1 15.4 10.6 14.5 27.2 28.9 14.7 58.7 12.2 13.9 28.5 28.6 13.1 14.3 14.9 19.7 11.9 28.6 14.0 14.8 15.7 10.7 13.0 15.0 16.6 11.4 16.4 27.9 12.8 13.5 16.1 29.7 14.8 11.7 13.6 13.8 17.3 15.3 29.2 24.6 57.2 21.3 39.2 34.0 41.0 39.4 33.3 32.5 38.7 30.6 68.6 24.0 73.5 29.1 45.5 38.2 64.8 54.2 41.3 38.0 42.6 45.1 32.6 52.7 105.2 30.4 62.3 21.7 30.0 49.0 55.3 59.1 23.5 41.8 45.3 71.8 20.6 37.5 66.8 44.5 42.2 43.0 96.7 51.2 62.0 41.2 81.5 31.4 18.8 50.3 25.5 34.3 23.8 39.2 21.1 48.3 26.5 36.1 26.7 26.3 61.8 58.8 27.4 65.5 51.2 34.3 40.1 40.7 27.8 19.6 23.2 24.0 16.6 22.1 23.8 34.4 23.6 21.6 20.6 38.2 28.2 27.9 23.0 17.3 20.6 38.8 23.8 27.9 30.0 27.3 32.5 27.2 28.9 28.5 28.6 28.6 27.9 29.7 29.2 9.9 0.0 11.3 13.1 9.9 14.5 17.2 23.4 28.5 12.1 9.1 11.2 9.5 10.0 8.5 5.5 8.4 36.1 7.8 8.7 25.4 13.9 85.2 8.6 11.9 13.1 2.4 13.5 25.2 13.3 32.2 17.4 10.2 8.5 5.1 10.4 10.0 54.8 20.9 13.5 24.0 11.9 10.2 7.7 10.8 19.2 16.1 7.4 8.8 6.5 31.6 12.0 14.4 9.0 17.2 10.0 4.9 18.8 16.8 24.9 9.2 23.2 8.0 17.1 0.0 13.5 13.5 7.0 11.2 20.0 12.9 12.7 13.0 13.1 15.9 15.6 RAD51C "FANCO, RAD51L2" ENSG00000108384 "RAD51 paralog C" O43502 17 58692573-58735611 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Disease variant, Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 117.7;Spermatocytes: 140.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 319.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA045198 Supported "Nucleoplasm,Vesicles,Cell Junctions,Mitochondria,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Mitochondria, Cytosol" "Vesicles, Cell Junctions" "HPA045198: AB_2679250" "unprognostic (5.39e-3)" "unprognostic (2.39e-2)" "unprognostic (1.23e-2)" "unprognostic (6.20e-2)" "unprognostic (1.83e-1)" "unprognostic (4.59e-2)" "prognostic unfavorable (8.68e-5)" "unprognostic (3.65e-2)" "unprognostic (2.91e-2)" "unprognostic (1.03e-2)" "prognostic favorable (5.33e-4)" "unprognostic (2.55e-1)" "unprognostic (2.62e-2)" "unprognostic (7.62e-2)" "unprognostic (2.41e-1)" "unprognostic (9.52e-2)" "unprognostic (2.42e-2)" 10.8 20.2 15.5 10.0 15.7 23.1 15.3 19.0 18.4 10.8 13.4 12.4 7.5 12.6 22.0 13.0 11.2 11.0 25.7 16.4 15.0 12.8 13.3 8.8 22.0 14.9 13.8 12.5 10.6 20.1 10.5 15.1 16.0 17.4 14.5 13.5 10.7 12.0 18.3 10.6 8.7 13.8 13.2 12.2 11.6 20.2 14.6 21.2 12.3 17.3 19.1 10.9 8.6 18.2 63.7 72.1 43.3 48.5 22.9 19.6 100.1 34.2 14.5 43.5 55.3 31.0 39.3 37.4 48.9 23.5 58.8 23.3 59.5 46.6 81.7 91.6 123.0 53.0 84.6 119.4 23.3 69.1 45.0 12.1 42.2 47.8 38.6 24.0 50.0 60.9 83.6 48.5 37.0 319.1 96.8 95.3 12.1 42.5 66.5 62.1 69.5 69.8 26.9 39.6 54.3 49.6 27.3 12.0 53.5 11.1 39.2 71.6 16.5 37.6 100.1 34.3 42.4 44.1 187.2 111.5 38.3 67.1 42.0 27.6 9.2 12.5 15.6 14.3 15.2 18.0 16.9 17.2 15.9 17.3 18.2 17.4 5.1 15.0 12.5 14.3 27.1 11.0 15.5 15.7 19.0 18.4 16.4 15.0 14.9 13.8 16.0 13.2 14.6 18.2 20.5 19.2 13.9 10.1 20.5 11.9 18.7 42.9 15.9 15.0 25.1 34.0 63.7 7.2 20.9 16.5 6.2 67.8 15.0 7.1 58.7 25.7 117.7 17.3 13.0 19.3 6.7 43.8 21.5 18.6 94.1 19.8 7.1 13.0 22.9 23.3 15.7 15.7 33.4 16.8 17.7 11.7 32.6 16.1 47.7 65.4 17.4 21.8 24.9 13.1 18.7 31.3 21.6 23.1 22.8 13.0 10.4 15.4 28.5 17.2 5.7 24.6 14.1 26.9 32.9 14.7 23.9 140.7 98.3 15.9 10.7 36.3 20.5 28.2 15.3 13.9 RAD52 ENSG00000002016 "RAD52 homolog, DNA repair protein" P43351 12 911736-990053 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 34.9;Excitatory neurons: 38.0;Inhibitory neurons: 48.8;Microglial cells: 23.4;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028957 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "Plasma membrane" "HPA028957: AB_2672842" "unprognostic (4.53e-1)" "unprognostic (8.08e-3)" "unprognostic (4.68e-2)" "unprognostic (5.27e-2)" "unprognostic (7.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.82e-3)" "unprognostic (1.88e-1)" "unprognostic (2.80e-2)" "unprognostic (8.43e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-1)" "prognostic unfavorable (2.22e-6)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (3.74e-2)" 4.9 4.7 5.9 5.0 8.2 3.6 6.0 7.8 8.4 8.8 5.1 7.2 5.8 7.3 8.4 4.7 6.6 4.2 4.7 7.1 7.0 7.6 6.4 4.0 6.3 7.2 7.3 10.8 6.6 4.9 5.2 5.4 7.6 6.2 7.0 6.8 4.4 6.0 12.3 9.8 6.6 6.1 5.3 6.0 5.5 4.4 7.8 7.0 8.3 6.8 5.9 6.1 5.8 13.7 4.0 15.2 11.6 13.8 12.1 9.7 12.7 7.9 7.5 9.0 8.7 14.8 14.3 12.8 2.4 8.2 7.4 12.0 9.4 5.4 7.7 17.7 8.2 14.6 16.2 10.0 7.0 15.6 4.2 5.5 9.4 9.1 28.3 17.6 7.4 12.4 9.8 7.5 8.6 8.7 10.8 15.7 15.4 10.0 9.9 10.8 11.6 4.8 9.4 7.1 4.3 5.0 10.3 10.8 6.0 16.8 10.2 7.5 7.4 12.3 14.6 9.8 8.6 2.7 4.6 13.5 6.3 6.9 4.5 7.0 2.1 1.5 2.9 1.9 3.5 2.9 3.0 2.5 2.7 4.0 3.3 3.2 2.0 2.6 2.5 6.0 2.9 1.0 5.9 8.2 7.8 8.4 7.1 7.0 7.2 7.3 7.6 5.3 7.8 13.7 2.5 3.2 5.9 34.9 3.4 1.8 1.4 1.7 4.0 4.2 2.7 2.7 3.6 2.8 3.2 3.7 2.1 4.8 4.5 5.9 1.9 2.3 4.0 2.3 4.5 3.4 1.8 4.2 38.0 1.6 2.8 3.3 5.1 2.6 5.7 4.5 0.7 2.6 2.5 3.3 48.8 2.0 0.0 1.0 2.9 7.5 0.6 2.6 0.0 23.4 2.8 1.4 1.0 30.2 54.5 0.9 3.4 0.7 2.3 1.6 3.9 1.8 1.7 2.6 6.6 4.2 3.9 4.0 4.7 1.9 1.0 2.1 2.6 2.2 3.3 0.8 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Basal prostatic cells: 11.3;Basal respiratory cells: 6.4;Prostatic glandular cells: 7.1;Squamous epithelial cells: 7.2;Suprabasal keratinocytes: 17.0;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 14.3" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.2 0.3 17.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.7 14.3 0.3 0.4 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 2.6 0.7 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 11.3 6.4 1.2 0.0 0.4 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 0.0 2.8 0.8 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.1 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.0 0.1 7.2 17.0 0.0 0.0 0.0 0.1 8.1 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RAI2 ENSG00000131831 "Retinoic acid induced 2" Q9Y5P3 X 17800049-17861337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 41.9;Leydig cells: 49.0;Peritubular cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enriched" "Detected in some" 10 "ASC diff: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051054 Uncertain Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA051054: AB_2681328" "unprognostic (3.45e-2)" "unprognostic (9.61e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (1.44e-1)" "unprognostic (1.49e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.31e-2)" "prognostic favorable (3.39e-14)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "unprognostic (1.82e-2)" "unprognostic (2.80e-2)" 48.0 17.3 9.4 8.3 10.4 0.2 47.2 8.8 11.9 55.3 7.4 33.0 6.7 66.8 9.9 15.5 71.8 24.7 32.9 9.9 9.3 14.4 3.9 28.6 9.6 9.4 8.5 50.9 14.3 10.8 19.3 7.8 9.6 31.8 8.1 8.9 13.8 31.8 12.5 20.3 23.0 30.1 8.6 4.5 28.2 6.0 10.4 5.0 21.6 17.1 9.6 38.9 43.7 8.7 0.0 0.0 0.2 0.0 104.3 10.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.7 0.2 0.6 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.1 1.9 0.0 0.6 0.0 0.0 0.0 5.8 0.0 1.1 1.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.8 0.0 0.1 0.0 0.0 0.0 0.1 9.4 10.4 8.8 11.9 9.9 9.3 9.4 8.5 9.6 8.6 10.4 8.7 25.0 12.8 4.5 2.0 0.0 4.1 9.3 0.0 0.6 14.0 13.4 10.4 13.0 12.8 0.6 22.0 0.0 0.1 0.3 0.3 5.9 8.2 0.3 25.0 16.5 15.2 27.6 0.0 10.5 9.8 0.1 24.8 7.7 41.9 0.0 9.7 10.8 0.1 0.5 26.9 17.9 0.7 0.0 0.0 4.2 3.3 49.0 0.9 5.4 14.0 0.6 20.5 0.0 5.0 0.4 4.9 17.5 70.7 0.1 7.9 1.3 1.9 4.4 3.0 0.0 21.0 8.7 0.4 2.7 0.5 2.8 0.0 1.3 0.2 1.6 5.1 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 212.2;Microglial cells: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 91.5;SCLC-21H: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA042707: AB_2678124, HPA043622: AB_2678585" "unprognostic (7.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (1.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.34e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-2)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "prognostic favorable (3.77e-5)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (5.33e-2)" 16.7 6.5 4.6 6.1 6.2 20.6 15.0 10.8 7.6 9.6 5.7 12.2 10.3 8.7 3.7 8.8 10.8 11.3 7.9 4.3 4.8 10.2 27.3 25.2 6.4 6.9 8.0 7.4 17.0 13.1 14.5 17.6 7.5 13.1 12.6 13.4 15.1 5.5 34.4 16.9 10.5 7.0 2.8 7.5 18.3 10.1 13.1 8.0 21.1 21.0 5.4 12.6 8.4 9.5 7.0 4.4 9.2 4.7 5.1 3.6 10.1 1.8 2.0 2.1 3.0 3.8 9.5 3.2 6.1 3.0 10.6 7.1 9.4 8.6 4.0 16.1 4.6 11.1 2.5 6.7 1.8 14.0 6.4 3.1 6.4 3.5 1.7 3.9 13.1 14.9 2.2 6.0 3.8 4.9 5.6 18.5 3.8 22.8 3.9 7.6 6.2 4.5 7.4 91.5 51.4 4.5 6.9 5.2 6.1 8.9 3.6 13.7 3.3 3.7 3.6 2.7 2.6 3.5 2.6 1.8 3.1 9.1 5.4 4.4 1.1 3.6 0.8 0.4 1.2 1.1 0.5 0.8 0.5 0.8 1.0 1.1 4.4 2.7 1.0 1.2 1.0 0.3 4.6 6.2 10.8 7.6 4.3 4.8 6.9 8.0 7.5 2.8 13.1 9.5 90.7 6.4 42.5 212.2 9.7 10.6 10.1 25.9 6.8 47.8 13.5 7.7 9.1 41.5 27.0 14.7 27.1 10.6 14.6 24.7 1.9 23.9 28.9 61.0 16.4 80.1 24.6 10.7 87.3 24.9 4.9 7.6 51.5 123.0 8.2 97.3 67.1 47.4 12.8 52.2 122.0 20.7 40.7 18.3 10.3 7.3 1.8 13.0 8.8 145.2 18.2 8.8 10.3 122.2 111.1 19.5 21.0 6.8 4.8 20.5 20.6 12.5 43.1 13.5 13.1 16.4 9.7 12.3 11.1 15.3 16.6 11.2 14.3 19.7 30.6 25.0 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RAPGEF2 "DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF" ENSG00000109756 "Rap guanine nucleotide exchange factor 2" Q9Y4G8 4 159103013-159360174 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, GTPase activation, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 456.2;Inhibitory neurons: 264.1;Microglial cells: 238.9;Oligodendrocyte precursor cells: 199.0;Oligodendrocytes: 236.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 5.9" "Group enriched" "Detected in many" 5 "granulocytes: 5.9;NK-cells: 3.3" "Cell line enhanced" "Detected in many" "HMC-1: 104.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068798 Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA068798: " "unprognostic (4.88e-2)" "unprognostic (7.42e-2)" "unprognostic (1.67e-2)" "unprognostic (7.79e-3)" "unprognostic (8.16e-2)" "unprognostic (4.71e-3)" "unprognostic (4.20e-3)" "unprognostic (2.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (9.71e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.76e-7)" "unprognostic (2.29e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" 22.7 9.4 8.7 13.4 19.8 87.5 24.1 4.1 32.1 16.7 0.0 21.8 15.9 16.1 9.8 13.8 14.0 20.1 23.2 27.4 0.3 22.7 30.5 26.6 11.9 0.0 0.7 13.5 19.5 23.5 15.3 38.5 0.3 12.2 20.8 35.1 25.3 12.6 21.7 17.5 17.0 19.7 0.6 29.7 19.3 9.8 6.0 17.5 39.5 31.4 11.5 14.8 11.8 18.6 8.9 11.9 55.4 17.2 21.4 23.9 84.9 17.0 21.3 15.2 10.9 36.7 19.4 50.7 6.1 17.0 22.0 8.0 19.1 21.8 18.0 8.6 13.2 79.0 25.3 21.4 15.5 9.7 104.5 14.1 12.1 36.5 12.9 32.0 44.1 20.7 17.6 46.0 19.0 15.6 24.1 1.5 23.7 10.4 11.8 19.7 14.0 2.0 13.6 20.2 15.7 21.0 24.9 12.1 20.0 26.5 6.0 6.3 47.0 23.9 25.2 30.7 14.2 51.0 32.9 0.8 28.3 4.1 14.8 2.2 1.0 0.7 0.5 0.5 0.6 0.2 0.4 0.3 0.5 0.2 0.6 0.3 5.9 3.3 0.6 1.0 1.0 0.3 8.7 19.8 4.1 32.1 27.4 0.3 0.0 0.7 0.3 0.6 6.0 18.6 66.7 57.7 30.1 110.7 12.9 20.4 11.2 7.5 9.6 19.7 23.5 11.9 39.0 11.5 13.8 7.3 41.7 11.1 20.2 24.8 0.0 9.2 5.3 43.5 19.5 49.2 14.4 38.9 456.2 12.6 9.6 16.9 7.7 59.2 51.8 22.9 32.2 30.5 10.8 33.7 264.1 12.0 2.0 24.6 20.1 5.3 7.8 29.5 33.8 238.9 15.6 30.2 2.1 199.0 236.2 22.1 17.7 8.6 40.5 17.6 7.1 8.7 18.7 22.4 52.6 28.1 37.2 3.5 8.9 10.7 20.0 5.9 12.9 7.2 7.9 15.1 RAPH1 "ALS2CR18, ALS2CR9, KIAA1681" ENSG00000173166 "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1" Q70E73 2 203394345-203535335 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 61.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 84.0;Hepatic stellate cells: 103.5;Microglial cells: 92.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016744, HPA020027" Approved Approved "Nuclear bodies,Plasma membrane,Cytosol" NA NA 69000000 "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Nuclear bodies, Plasma membrane" Cytosol "HPA016744: AB_1844781, HPA020027: AB_1844782" "unprognostic (9.78e-2)" "unprognostic (9.05e-2)" "unprognostic (7.17e-4)" "unprognostic (1.04e-1)" "unprognostic (1.58e-1)" "unprognostic (1.83e-1)" "unprognostic (8.32e-2)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (1.31e-1)" "unprognostic (1.24e-4)" "unprognostic (1.92e-1)" "unprognostic (1.40e-2)" "unprognostic (5.11e-2)" "unprognostic (2.30e-1)" "unprognostic (1.19e-2)" "unprognostic (2.79e-1)" 11.1 6.5 1.5 5.2 4.6 3.1 13.3 1.3 7.9 9.4 0.3 7.0 7.8 5.6 4.6 8.8 5.1 8.9 5.9 5.0 8.5 7.2 61.6 14.3 3.7 2.4 7.0 2.0 6.4 5.6 3.6 13.0 4.1 6.6 7.3 7.3 8.6 4.3 6.6 8.9 7.9 7.8 0.1 16.9 8.8 9.4 2.7 2.6 30.0 6.2 4.9 7.7 6.6 2.2 11.1 7.5 15.6 9.0 12.0 15.4 14.7 15.1 11.0 15.3 19.1 35.0 11.4 0.0 3.7 23.1 11.2 5.8 8.2 12.9 31.7 2.2 4.6 0.0 17.9 6.2 30.0 0.1 0.2 21.5 10.7 28.1 29.4 16.8 24.2 1.7 0.8 8.2 31.0 6.2 0.1 0.0 9.2 5.7 10.0 0.2 22.0 6.9 11.2 34.9 5.5 7.5 10.3 9.8 12.5 20.4 5.5 0.5 29.0 37.5 12.5 18.2 16.1 3.8 7.7 0.1 30.9 0.2 8.4 0.0 0.2 0.0 0.0 0.7 0.1 0.0 0.1 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.1 0.0 1.5 4.6 1.3 7.9 5.0 8.5 2.4 7.0 4.1 0.1 2.7 2.2 36.3 16.0 8.4 12.7 1.2 49.1 20.7 10.3 16.5 11.3 21.6 9.4 1.1 15.7 9.7 14.7 14.6 8.9 0.8 32.9 7.9 6.3 14.4 24.4 17.7 29.0 2.4 3.2 84.0 9.3 7.6 23.4 47.9 65.7 1.3 6.2 103.5 79.6 18.1 10.1 56.7 8.6 4.1 17.8 51.1 4.9 4.7 28.8 12.4 92.8 3.3 18.6 0.0 41.2 9.1 20.5 21.3 4.9 0.1 19.0 22.4 2.8 5.2 4.4 19.7 26.8 33.4 29.3 19.6 26.9 40.9 10.9 2.8 0.9 13.3 28.4 RAPSN "CMS1D, CMS1E, RNF205" ENSG00000165917 "Receptor associated protein of the synapse" Q13702 11 47437764-47449143 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 23 "skeletal muscle: 88.9;tongue: 33.1" "Cell type enriched" "Detected in some" 4 "Skeletal myocytes: 63.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 238.7" "Low region specificity" "Detected in some" HPA039475 Approved Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Centrosome, Cytosol" "HPA039475: AB_10794196" "unprognostic (5.37e-2)" "unprognostic (1.02e-1)" "unprognostic (7.34e-2)" "unprognostic (4.58e-2)" "unprognostic (2.95e-2)" "unprognostic (1.44e-1)" "unprognostic (2.62e-2)" "unprognostic (1.77e-3)" "unprognostic (1.35e-1)" "unprognostic (5.38e-2)" "unprognostic (4.81e-2)" "unprognostic (2.89e-2)" "unprognostic (1.08e-2)" "unprognostic (1.64e-4)" "unprognostic (3.83e-1)" "unprognostic (4.73e-3)" "unprognostic (4.48e-2)" 0.3 1.5 0.5 0.2 0.5 0.3 0.2 0.3 1.2 0.2 0.9 0.8 0.1 0.0 0.1 1.2 0.1 0.1 2.6 0.5 0.5 0.3 0.5 0.4 0.2 0.3 0.5 0.0 0.2 0.0 0.1 2.1 0.5 0.7 0.0 0.1 1.3 0.0 88.9 0.5 0.5 0.1 0.4 0.6 0.2 0.3 0.6 0.1 0.2 33.1 0.1 0.1 0.1 0.5 0.0 0.2 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.2 0.3 0.2 0.7 0.1 0.2 1.2 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 59.6 0.0 0.0 0.2 0.0 0.0 0.2 0.0 238.7 0.0 0.3 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.1 0.3 0.1 0.3 0.3 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.3 1.2 0.5 0.5 0.3 0.5 0.5 0.4 0.6 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.3 1.4 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.5 2.7 0.3 0.1 0.2 0.0 0.0 0.1 0.2 0.1 1.0 0.0 0.5 0.0 0.2 0.0 0.8 0.2 0.0 0.0 0.0 0.0 0.3 0.3 13.8 0.0 0.5 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.8 0.0 0.0 0.1 0.2 0.0 0.0 1.1 0.0 0.0 63.8 0.5 0.0 0.4 0.0 0.0 0.3 0.4 0.1 0.2 0.1 RASA4 "CAPRI, GAPL, KIAA0538" ENSG00000105808 "RAS p21 protein activator 4" O43374 7 102573807-102616756 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "skeletal muscle: 254.9;tongue: 88.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 73.9;Enteroendocrine cells: 71.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-138 MG: 48.9" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 56: Bipolar cells - Visual perception" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (6.44e-2)" "unprognostic (3.64e-2)" "unprognostic (8.93e-3)" "unprognostic (1.69e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (3.44e-1)" "unprognostic (7.45e-2)" "unprognostic (2.92e-1)" "unprognostic (2.29e-1)" "unprognostic (4.62e-3)" "unprognostic (4.19e-2)" "unprognostic (4.81e-2)" "unprognostic (8.87e-3)" "unprognostic (2.47e-2)" "unprognostic (3.34e-1)" "unprognostic (1.18e-2)" 38.9 17.5 22.9 10.8 18.8 6.0 31.2 22.7 23.0 37.4 3.6 29.8 10.9 37.7 4.7 10.8 28.4 6.3 14.5 22.5 22.8 29.2 2.6 22.1 13.8 21.5 25.9 25.2 12.3 12.8 24.2 13.0 17.3 23.4 4.0 13.3 12.9 18.0 254.9 17.3 21.6 7.5 17.2 16.8 16.1 5.4 22.7 4.8 17.3 88.6 7.1 26.0 29.0 16.3 1.1 1.5 14.1 2.6 1.8 5.8 0.6 16.3 7.6 4.3 4.9 6.1 3.1 9.9 11.9 24.0 0.3 12.7 0.6 0.1 1.7 1.7 2.4 3.2 4.1 1.0 2.1 2.0 4.4 6.4 1.4 1.4 0.4 18.7 2.7 6.5 5.9 17.0 1.4 4.0 8.6 7.1 1.0 6.6 7.3 17.5 2.9 16.5 0.4 5.0 12.7 25.3 2.3 2.3 1.9 7.5 1.1 5.7 3.0 48.9 22.3 4.9 4.1 28.9 18.5 7.7 4.3 4.5 5.9 0.4 7.9 0.2 1.3 8.6 3.0 3.2 2.4 1.8 10.9 2.9 2.5 1.5 1.8 1.4 1.1 9.2 3.3 3.8 22.9 18.8 22.7 23.0 22.5 22.8 21.5 25.9 17.3 17.2 22.7 16.3 26.8 12.8 10.9 15.0 8.3 3.8 4.5 1.3 0.6 73.9 2.0 3.0 1.1 2.8 5.2 3.7 16.7 0.2 7.2 5.9 13.7 1.1 0.4 3.3 13.0 24.9 71.8 5.7 5.6 0.7 0.2 5.0 3.1 2.9 1.3 13.6 3.3 1.4 6.0 28.6 6.6 11.8 0.0 11.6 22.8 0.3 8.4 13.3 1.8 4.7 14.2 9.4 6.2 5.5 1.4 1.7 2.8 7.9 4.0 2.9 19.9 8.4 6.2 11.7 13.1 21.3 10.0 3.4 3.3 1.3 3.4 0.4 6.4 5.6 2.9 4.1 RASA4B ENSG00000170667 "RAS p21 protein activator 4B" C9J798 7 102479976-102517777 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "skeletal muscle: 130.9" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Bipolar cells: 3.3;Cardiomyocytes: 3.9;Gastric mucus-secreting cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.2;intermediate monocyte: 2.0;myeloid DC: 3.3;plasmacytoid DC: 2.1" "Group enriched" "Detected in many" 6 "dendritic cells: 3.3;monocytes: 2.2" "Cell line enhanced" "Detected in many" "SH-SY5Y: 15.1;U-138 MG: 17.0;U-2 OS: 14.9" "Low region specificity" "Detected in all" HPA043010 Uncertain Approved "Vesicles,Cell Junctions" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" Vesicles "Cell Junctions" "HPA043010: AB_2678267" "unprognostic (1.05e-2)" "unprognostic (1.34e-2)" "unprognostic (1.03e-2)" "unprognostic (1.96e-1)" "unprognostic (1.42e-2)" "unprognostic (1.40e-1)" "unprognostic (4.15e-2)" "unprognostic (1.55e-1)" "unprognostic (2.10e-1)" "unprognostic (6.79e-2)" "unprognostic (3.08e-3)" "unprognostic (2.31e-1)" "unprognostic (5.44e-4)" "unprognostic (1.18e-2)" "unprognostic (3.77e-2)" "unprognostic (4.37e-3)" "unprognostic (1.10e-1)" 14.0 5.8 6.5 4.2 6.1 2.2 10.8 6.3 7.9 13.3 3.0 11.9 6.4 16.5 1.3 2.8 9.7 3.7 4.7 6.2 8.0 6.4 0.8 6.0 4.7 7.8 8.3 9.6 2.4 5.2 5.8 4.9 6.7 8.1 1.8 5.3 4.5 7.6 130.9 5.5 7.8 3.8 6.6 5.9 4.9 2.1 7.6 1.9 3.8 19.2 2.8 9.5 9.5 7.5 0.2 1.4 3.7 0.5 1.3 2.9 0.2 6.8 4.4 2.2 3.6 0.5 1.1 3.4 7.3 8.6 0.7 9.1 0.0 0.0 1.1 0.5 1.6 0.5 2.7 0.8 1.2 0.3 0.5 2.9 0.8 0.1 0.2 10.4 0.9 1.7 0.9 9.8 0.7 3.0 2.9 1.9 0.3 1.7 1.9 2.8 1.5 4.6 0.1 0.9 3.1 15.1 1.0 0.5 0.5 3.0 1.0 2.0 2.0 17.0 14.9 1.8 0.6 3.5 2.9 2.4 2.3 0.9 2.8 0.0 2.2 0.0 0.3 2.0 0.2 0.1 0.3 0.1 3.3 0.2 0.3 0.4 0.3 0.0 0.4 2.1 0.3 1.2 6.5 6.1 6.3 7.9 6.2 8.0 7.8 8.3 6.7 6.6 7.6 7.5 0.6 0.0 0.6 2.9 1.1 0.4 0.2 0.0 1.2 3.3 0.1 0.3 3.9 0.0 0.0 0.0 0.0 0.0 0.1 0.3 1.9 0.1 0.0 0.1 0.3 1.8 2.4 0.4 0.5 0.2 0.0 0.3 5.6 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.8 1.3 0.0 0.6 0.9 0.0 0.3 1.0 0.0 1.0 0.6 0.6 0.0 1.5 0.0 0.1 0.0 0.0 2.5 0.2 1.3 0.3 0.1 0.6 0.0 0.5 0.8 0.3 0.0 0.3 1.1 0.1 1.6 0.3 0.0 0.2 RASAL1 RASAL ENSG00000111344 "RAS protein activator like 1" O95294 12 113098819-113136239 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 59.8;salivary gland: 28.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 36.8;Excitatory neurons: 14.0;Gastric mucus-secreting cells: 57.1;Oligodendrocytes: 46.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 15.3;EFO-21: 19.3;REH: 22.3;RPMI-8226: 50.0;RPTEC TERT1: 19.0;U-698: 42.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041650 Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 25: RPMI-8226 - Immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "Cell Junctions" "HPA041650: AB_2677598" "unprognostic (9.95e-2)" "unprognostic (1.11e-2)" "unprognostic (5.44e-3)" "prognostic unfavorable (3.26e-5)" "unprognostic (1.27e-2)" "unprognostic (7.73e-3)" "unprognostic (1.57e-2)" "unprognostic (1.43e-2)" "unprognostic (2.65e-1)" "unprognostic (3.02e-3)" "unprognostic (3.16e-2)" "unprognostic (2.53e-1)" "unprognostic (1.74e-2)" "unprognostic (2.85e-3)" "unprognostic (1.15e-1)" "unprognostic (3.34e-2)" "unprognostic (2.64e-1)" 0.0 15.4 10.9 1.2 13.8 0.5 1.0 0.5 19.1 3.5 1.1 1.7 0.4 0.1 0.1 22.6 1.6 0.3 0.0 23.6 4.0 17.2 0.1 0.2 1.1 1.7 4.3 0.0 1.1 59.8 5.0 0.2 1.8 0.2 1.1 0.5 28.5 3.9 0.0 11.4 0.5 0.0 0.6 0.2 10.6 0.7 7.7 0.2 10.1 0.0 2.7 0.2 5.3 12.1 0.7 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 3.9 15.3 19.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.3 0.0 4.3 0.0 0.0 0.6 5.5 0.0 22.3 0.0 50.0 19.0 0.0 0.5 0.0 0.0 7.2 0.0 0.1 2.9 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 42.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 13.8 0.5 19.1 23.6 4.0 1.7 4.3 1.8 0.6 7.7 12.1 0.0 0.0 0.0 1.3 0.8 0.5 0.0 0.4 0.0 0.5 2.4 2.0 4.3 2.8 1.0 36.8 0.0 1.1 0.0 1.9 0.0 1.4 0.1 1.8 0.6 0.3 1.2 0.0 14.0 0.0 0.2 0.3 57.1 4.6 2.5 0.0 0.0 0.0 0.4 0.0 1.0 4.8 0.0 0.0 5.5 0.2 0.0 1.2 1.8 0.0 1.0 2.7 0.0 0.0 46.5 5.2 3.3 0.0 0.6 0.0 0.1 5.2 0.5 0.0 0.0 0.0 0.2 0.1 0.7 4.6 1.1 1.2 0.4 0.1 3.3 0.6 RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 505.8;Inhibitory neurons: 398.4;Microglial cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" 10.3 3.6 1.7 2.8 3.2 0.6 8.0 0.0 7.4 7.3 0.1 4.2 2.7 6.1 3.6 17.0 5.5 7.5 13.6 4.3 0.8 5.8 3.0 9.4 1.8 0.0 1.0 3.6 4.6 4.6 5.9 9.4 0.0 5.0 4.4 28.9 6.6 4.4 4.6 7.0 3.4 6.6 0.0 3.2 3.7 8.9 5.1 1.8 5.3 10.0 2.9 5.0 10.5 2.4 30.9 8.9 12.1 4.2 8.6 11.6 17.3 13.2 13.6 11.7 8.5 14.8 15.6 0.0 23.0 13.2 19.7 25.2 10.2 23.0 10.7 0.0 5.0 0.0 9.8 7.1 10.0 4.7 0.5 35.1 5.2 13.4 54.1 13.7 10.3 0.0 1.0 0.0 16.5 3.2 0.0 4.2 10.1 6.4 1.8 0.1 5.2 0.0 7.2 3.6 8.8 4.4 10.9 9.5 9.0 10.8 10.4 5.5 18.9 15.1 15.7 17.2 21.0 6.5 0.1 0.1 13.3 2.4 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 3.2 0.0 7.4 4.3 0.8 0.0 1.0 0.0 0.0 5.1 2.4 99.8 76.9 12.9 47.3 1.0 15.9 10.0 15.7 8.0 50.7 17.8 11.7 37.4 17.2 18.2 16.5 152.2 15.0 1.0 9.0 5.9 21.8 17.4 33.6 43.0 66.2 34.1 0.0 505.8 12.5 16.4 18.4 17.9 27.6 7.6 19.0 35.3 6.7 16.8 84.1 398.4 15.7 6.1 4.5 21.6 7.3 19.6 16.5 3.6 271.7 8.5 24.7 0.0 154.3 101.3 33.6 5.2 23.0 2.9 32.6 4.9 6.6 34.7 175.5 65.7 22.7 56.9 40.5 34.5 17.8 24.2 41.9 2.3 8.3 12.6 38.2 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASD1 "AGS1, DEXRAS1" ENSG00000108551 "Ras related dexamethasone induced 1" Q9Y272 17 17494437-17496395 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 371.9" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 425.1;Muller glia cells: 375.3;Peritubular cells: 469.8;Sertoli cells: 565.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 160.1" "Lineage enriched" "Detected in many" 46 "dendritic cells: 160.1" "Group enriched" "Detected in some" 4 "ASC diff: 70.2;REH: 71.0" "Group enriched" "Detected in all" 5 "basal ganglia: 75.6;hippocampal formation: 54.9;thalamus: 53.2" "Low region specificity" "Detected in all" HPA047896 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA047896: AB_10960535" "unprognostic (1.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "unprognostic (3.31e-2)" "unprognostic (6.40e-2)" "unprognostic (8.13e-2)" "unprognostic (8.65e-2)" "unprognostic (7.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.17e-3)" "unprognostic (2.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" 244.7 53.5 48.7 5.9 63.7 9.3 153.3 31.1 83.6 69.2 13.4 16.1 5.4 22.8 11.9 11.7 32.7 12.6 91.0 60.8 61.9 181.7 271.3 25.4 3.0 71.6 49.8 53.7 30.1 4.2 371.9 1.3 39.4 32.7 6.5 47.7 97.8 55.7 183.1 44.1 12.2 3.4 45.7 18.6 42.2 47.7 40.4 13.1 88.4 103.0 1.2 16.6 26.3 53.6 0.0 0.3 0.3 0.0 70.2 3.8 0.3 0.9 1.4 0.1 0.2 3.0 0.0 0.0 8.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.9 0.3 0.3 8.3 0.5 0.1 0.3 17.1 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 0.2 7.5 13.8 1.3 1.4 1.3 4.5 71.0 0.1 0.1 1.5 0.0 12.9 0.4 1.1 0.9 16.3 2.1 0.1 0.1 4.1 0.1 0.7 0.5 0.2 14.5 0.6 0.2 0.4 0.0 0.5 0.0 0.4 0.0 0.4 3.5 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.8 160.1 0.1 1.0 48.7 63.7 31.1 83.6 60.8 61.9 71.6 49.8 39.4 45.7 40.4 53.6 172.2 28.9 36.8 21.2 11.0 17.2 96.2 46.6 27.3 51.4 106.9 147.2 71.2 20.0 33.5 149.0 4.2 3.3 45.8 42.9 13.7 93.5 2.7 150.9 264.2 31.1 222.4 0.4 15.0 1.3 2.2 191.1 86.6 425.1 8.8 40.3 9.7 21.6 3.6 6.7 5.2 262.7 260.4 3.1 22.2 8.1 109.6 27.3 30.2 1.9 2.2 375.3 0.0 17.1 1.6 9.0 21.8 469.8 56.1 73.3 16.8 13.8 7.2 23.8 565.4 228.1 191.7 1.7 3.0 54.8 13.2 6.7 27.0 73.7 32.9 20.0 RASD2 "MGC:4834, Rhes, TEM2" ENSG00000100302 "RASD family member 2" Q96D21 22 35540831-35553999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 212.9" "Group enriched" "Detected in some" 4 "Intestinal goblet cells: 13.1;Sertoli cells: 46.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 212.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.1;hTERT-RPE1: 9.8;SK-BR-3: 5.6;U-2 OS: 3.1;U-87 MG: 4.0" "Region enriched" "Detected in all" 8 "basal ganglia: 589.6" "Region enriched" "Detected in all" 8 "basal ganglia: 429.3" HPA005839 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA005839: AB_1079745" "unprognostic (1.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.33e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (7.07e-3)" "unprognostic (9.76e-2)" "unprognostic (5.49e-2)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.00e-3)" "prognostic unfavorable (2.22e-5)" "unprognostic (3.75e-2)" "unprognostic (1.61e-1)" "unprognostic (8.42e-3)" "unprognostic (6.22e-2)" 1.8 7.3 30.8 2.5 212.9 3.8 2.3 0.0 30.7 3.1 0.0 28.2 2.3 4.7 15.0 1.9 5.6 2.2 8.6 12.5 9.9 1.5 0.4 3.2 0.4 4.6 12.5 1.2 1.6 1.2 2.1 0.2 6.4 15.2 4.0 0.5 4.0 22.7 15.0 1.6 6.2 7.3 1.8 0.2 3.8 0.7 48.4 0.7 1.2 4.5 1.2 4.3 2.5 9.0 0.1 2.2 0.0 0.4 0.0 0.0 0.0 0.5 0.2 0.8 0.6 0.1 0.4 0.0 0.1 1.9 3.1 0.1 0.1 0.0 0.7 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.1 2.5 1.6 0.2 9.8 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.0 1.5 0.2 1.6 5.6 0.0 0.1 0.4 0.1 0.0 1.3 3.1 0.1 0.7 1.4 0.5 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 212.9 0.0 30.7 12.5 9.9 4.6 12.5 6.4 1.8 48.4 9.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 1.7 2.9 3.3 1.9 0.0 0.2 0.0 0.0 0.0 0.7 3.0 0.0 0.2 0.1 0.1 0.2 2.9 0.0 0.0 3.2 0.2 0.0 3.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.6 13.1 2.0 0.0 0.8 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 1.0 0.7 0.0 2.3 0.7 0.0 0.5 0.1 0.0 0.1 0.2 46.0 0.4 6.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.5 0.3 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RASGRP4 ENSG00000171777 "RAS guanyl releasing protein 4" Q8TDF6 19 38409051-38426305 "Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 20.8;lymphoid tissue: 8.9" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 18.1;granulocytes: 26.6;Hofbauer cells: 15.1;Kupffer cells: 32.9;Langerhans cells: 11.6;Macrophages: 19.1;monocytes: 25.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 39.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 25.7;HMC-1: 24.0;U-937: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA041929 Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA041929: AB_10961405" "unprognostic (1.22e-1)" "unprognostic (1.31e-1)" "unprognostic (1.58e-1)" "unprognostic (1.17e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-2)" "unprognostic (1.39e-2)" "unprognostic (2.10e-1)" "unprognostic (2.00e-1)" "unprognostic (5.23e-4)" "unprognostic (6.54e-2)" "unprognostic (1.27e-1)" "unprognostic (2.30e-3)" "unprognostic (2.19e-2)" "unprognostic (1.05e-1)" "unprognostic (4.56e-1)" "unprognostic (2.66e-2)" 3.2 0.8 0.3 6.7 0.3 20.8 0.7 0.3 0.9 1.1 0.4 1.2 1.2 0.5 0.1 1.0 1.0 1.9 0.6 0.2 0.3 0.3 0.7 3.3 1.1 0.9 0.4 0.4 1.1 0.3 0.2 2.3 0.6 0.5 0.8 0.0 0.4 0.5 0.8 0.5 1.8 2.0 0.7 8.9 0.9 0.2 1.1 1.1 0.2 1.4 0.7 2.5 0.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 25.7 0.0 0.0 0.0 0.1 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 12.5 13.5 20.1 0.0 15.4 0.0 0.1 0.3 0.0 9.4 0.1 0.0 0.0 39.4 0.0 17.9 0.7 1.4 4.4 0.3 0.3 0.3 0.9 0.2 0.3 0.9 0.4 0.6 0.7 1.1 1.0 0.2 0.0 0.6 0.0 0.2 0.8 0.0 0.0 0.0 0.1 0.0 0.3 18.1 0.0 1.3 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.8 0.7 0.0 0.2 0.4 0.0 0.0 26.6 0.0 1.4 0.0 15.1 0.0 0.4 0.0 0.0 32.9 11.6 0.0 0.0 19.1 1.8 0.0 25.7 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.7 0.0 0.4 0.4 0.0 0.1 0.0 0.0 0.3 1.5 0.0 0.0 0.1 RASSF2 "CENP-34, KIAA0168" ENSG00000101265 "Ras association domain family member 2" P50749 20 4780023-4823608 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 217.0;retina: 162.8" "Cell type enhanced" "Detected in many" "Kupffer cells: 87.1;Langerhans cells: 75.8;monocytes: 148.5;Oligodendrocytes: 106.7;Peritubular cells: 149.7;Rod photoreceptor cells: 160.3" "Cancer enriched" "Detected in all" 5 "glioma: 48.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AN3-CA: 56.8;BEWO: 59.2;Daudi: 62.7;HL-60: 74.7;NB-4: 96.3;U-937: 116.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051200 Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 32: U-937 - Innate immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Golgi apparatus, Plasma membrane, Cytosol" "HPA051200: AB_2681386" "unprognostic (6.51e-2)" "unprognostic (3.67e-3)" "unprognostic (5.31e-2)" "unprognostic (1.47e-2)" "unprognostic (3.15e-1)" "unprognostic (1.46e-3)" "unprognostic (2.80e-1)" "unprognostic (7.01e-2)" "unprognostic (1.38e-2)" "unprognostic (2.41e-2)" "unprognostic (4.93e-2)" "unprognostic (3.90e-1)" "prognostic unfavorable (7.82e-4)" "unprognostic (3.51e-2)" "unprognostic (1.35e-1)" "unprognostic (3.49e-1)" "unprognostic (6.46e-2)" 16.4 9.7 76.1 47.1 135.2 91.2 6.9 155.5 113.5 27.9 40.0 8.4 5.3 25.4 22.5 10.0 22.1 15.6 4.2 68.9 94.7 4.0 5.9 25.4 58.6 217.0 148.8 7.0 3.1 1.5 5.0 9.1 186.4 7.3 9.6 162.8 3.0 9.3 1.2 4.2 14.5 38.7 135.8 32.7 7.0 20.6 120.0 19.5 4.7 5.0 73.6 20.7 4.9 197.0 0.1 14.5 34.9 56.8 0.4 0.0 59.2 3.5 10.0 0.6 0.2 3.4 0.1 62.7 5.6 3.1 1.4 0.2 5.1 0.0 0.8 22.7 2.1 41.1 0.0 0.7 0.0 74.7 40.1 0.1 0.0 1.3 0.0 1.3 23.4 7.0 0.2 24.0 0.0 0.1 11.0 96.3 7.8 0.0 1.1 17.1 3.9 23.8 0.0 29.0 0.4 2.8 0.0 1.0 1.7 7.4 0.0 47.0 0.7 1.5 7.4 0.7 4.6 0.3 5.9 37.8 0.3 116.8 0.4 85.6 61.5 101.3 7.7 50.1 14.6 24.3 12.0 10.4 46.8 16.4 7.8 6.5 139.5 8.5 59.9 30.7 11.8 42.1 76.1 135.2 155.5 113.5 68.9 94.7 217.0 148.8 186.4 135.8 120.0 197.0 5.5 0.0 8.7 7.5 49.3 4.7 0.0 0.1 0.0 39.2 4.1 1.7 1.9 1.5 1.9 0.0 27.1 3.0 43.0 0.1 1.9 1.2 6.0 3.2 19.6 18.6 0.0 6.1 1.5 0.9 5.1 10.9 1.1 1.0 54.3 4.5 11.4 1.2 27.1 6.7 1.3 0.7 0.0 87.1 75.8 25.1 33.2 64.6 8.8 26.2 148.5 19.3 7.2 33.7 106.7 0.6 0.0 149.7 14.3 1.2 0.0 0.3 0.1 160.3 0.0 9.4 3.5 0.7 1.0 0.3 2.6 1.4 20.8 0.8 0.0 2.3 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RASSF4 "AD037, MGC44914" ENSG00000107551 "Ras association domain family member 4" Q9H2L5 10 44959407-44995891 "Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 77.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 157.0;monocytes: 258.7;Muller glia cells: 260.3;Proximal tubular cells: 128.0;Skeletal myocytes: 186.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 84.8;intermediate monocyte: 63.9;myeloid DC: 84.2;non-classical monocyte: 37.9" "Group enriched" "Detected in many" 10 "dendritic cells: 84.2;monocytes: 84.8" "Cell line enhanced" "Detected in many" "Karpas-707: 64.3;RH-30: 162.7;RPMI-8226: 54.9;U-937: 85.4;WM-115: 54.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038834, HPA077069" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytokinetic bridge,Mitotic spindle,Cytosol" Yes NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytokinetic bridge, Mitotic spindle, Cytosol" "HPA038834: AB_10795576, HPA077069: " "unprognostic (1.83e-1)" "unprognostic (8.21e-3)" "unprognostic (1.21e-2)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (5.14e-2)" "unprognostic (3.15e-2)" "unprognostic (2.18e-2)" "unprognostic (8.81e-2)" "unprognostic (4.83e-2)" "unprognostic (8.75e-3)" "unprognostic (4.20e-1)" "unprognostic (4.11e-3)" "unprognostic (4.02e-2)" "unprognostic (2.22e-2)" "unprognostic (1.42e-1)" "unprognostic (6.20e-2)" 35.3 7.1 57.4 21.7 67.9 8.3 22.7 64.3 58.6 6.5 43.8 18.5 13.6 3.0 8.6 4.7 6.0 10.8 44.8 53.9 58.9 77.3 17.1 11.9 19.7 63.4 64.0 3.6 39.5 5.0 13.0 12.7 65.9 7.9 6.0 26.9 16.7 10.9 14.8 4.8 13.8 8.7 55.8 20.1 9.4 9.0 65.3 10.4 40.7 17.6 9.1 11.4 7.0 69.7 1.4 0.3 6.0 11.4 17.9 1.0 4.1 0.7 1.1 2.0 3.5 5.0 0.6 0.1 2.3 0.8 3.9 0.0 2.6 2.8 2.8 37.8 0.0 0.1 0.2 39.7 19.0 2.6 0.0 13.1 0.0 1.9 0.2 10.9 3.0 1.6 0.0 64.3 2.9 0.0 3.0 43.1 1.2 0.2 1.2 8.1 162.7 54.9 0.4 1.2 1.0 0.8 0.0 0.5 2.0 10.7 1.1 32.4 0.0 0.4 3.6 3.0 6.5 0.7 0.7 0.1 18.9 85.4 54.8 0.0 84.8 0.1 8.7 63.9 0.2 0.0 0.6 3.7 84.2 0.0 0.6 2.6 3.0 6.9 37.9 2.2 0.3 48.9 57.4 67.9 64.3 58.6 53.9 58.9 63.4 64.0 65.9 55.8 65.3 69.7 8.9 19.2 17.2 77.4 3.7 3.7 1.4 3.2 1.2 22.5 9.7 7.0 47.9 37.1 13.1 16.5 4.2 1.2 20.3 10.1 17.6 45.3 1.4 6.4 13.7 9.2 11.5 0.0 17.0 3.8 1.2 28.6 1.5 14.8 1.3 4.2 6.1 20.1 157.0 37.0 33.6 7.4 12.2 84.7 94.3 4.4 10.5 91.0 8.8 35.6 258.7 260.3 54.6 37.7 38.2 4.0 11.3 2.2 4.1 1.0 45.0 128.0 5.9 13.3 26.3 186.4 25.9 0.6 1.9 0.8 1.7 2.6 8.0 4.9 15.0 0.7 RC3H1 "KIAA2025, RNF198, roquin, RP5-1198E17.5" ENSG00000135870 "Ring finger and CCCH-type domains 1" Q5TC82 1 173931084-174022357 "Enzymes, Predicted intracellular proteins" "RNA-binding, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027428, HPA027434, HPA027448" Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" Cytosol "Golgi apparatus, Plasma membrane" "HPA027428: AB_10600324, HPA027434: AB_10601235, HPA027448: AB_10601683" "unprognostic (6.91e-2)" "unprognostic (7.76e-2)" "unprognostic (2.23e-2)" "unprognostic (2.33e-2)" "unprognostic (7.73e-2)" "unprognostic (1.61e-2)" "unprognostic (5.74e-2)" "unprognostic (1.99e-2)" "unprognostic (1.75e-1)" "unprognostic (1.13e-2)" "unprognostic (2.04e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (5.25e-2)" "unprognostic (2.15e-1)" "unprognostic (3.43e-3)" "unprognostic (6.83e-3)" 4.8 3.8 2.6 4.2 4.7 19.6 5.2 16.0 5.1 4.9 11.4 5.2 3.4 4.5 4.0 6.1 4.8 4.0 4.6 3.1 5.8 3.9 5.8 5.9 4.9 3.5 3.5 5.1 4.8 3.9 4.6 4.3 4.0 4.2 4.2 8.0 4.4 3.5 10.6 7.4 5.5 3.7 2.0 6.7 4.6 5.3 4.1 5.0 5.0 10.3 5.6 4.5 5.1 7.2 6.6 9.1 4.9 7.7 9.2 7.1 6.8 4.4 6.3 5.0 4.4 8.4 7.3 9.4 7.7 7.2 3.9 6.2 7.5 6.3 7.0 6.6 1.8 8.1 6.8 7.0 5.6 10.7 9.1 6.8 4.8 7.3 4.9 4.6 7.9 4.5 9.4 5.6 6.2 5.0 6.5 9.6 8.5 6.1 1.0 7.0 8.8 6.9 8.9 12.7 5.9 5.3 8.4 10.7 4.3 8.2 7.2 10.7 11.4 6.5 6.5 5.6 5.8 6.9 7.5 11.8 4.4 4.8 6.7 3.4 1.9 2.7 1.1 1.9 1.2 1.5 1.1 1.3 1.0 1.8 1.5 1.3 6.4 1.4 2.6 0.8 0.9 0.7 2.6 4.7 16.0 5.1 3.1 5.8 3.5 3.5 4.0 2.0 4.1 7.2 39.8 41.7 34.5 32.0 49.4 34.4 17.3 14.1 60.9 35.6 53.6 28.3 25.7 25.8 20.0 23.9 81.3 10.6 70.2 37.4 9.8 25.4 13.3 77.5 45.9 32.0 34.2 30.7 46.8 18.9 8.2 34.9 68.8 82.9 15.8 20.3 34.2 36.3 11.5 38.7 43.5 28.9 16.2 37.2 48.2 8.1 15.8 38.5 30.2 40.3 33.0 22.7 30.9 42.3 68.2 24.8 22.1 10.5 52.2 38.3 25.1 9.8 30.2 47.3 19.7 39.0 31.5 35.8 14.0 66.8 40.9 11.6 41.4 16.1 25.9 38.5 RCCD1 MGC14386 ENSG00000166965 "RCC1 domain containing 1" A6NED2 15 90954870-90963125 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039683, HPA040776" Enhanced Enhanced "Plasma membrane,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA039683: AB_10794752, HPA040776: AB_10795478" "unprognostic (1.01e-2)" "unprognostic (1.69e-2)" "unprognostic (7.22e-3)" "unprognostic (8.63e-2)" "unprognostic (6.18e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (5.86e-2)" "unprognostic (4.83e-2)" "unprognostic (5.10e-2)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" "unprognostic (1.49e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" 3.9 8.8 4.1 3.0 4.3 4.6 3.5 5.5 5.2 6.9 5.0 6.3 5.1 5.5 3.5 6.6 6.0 2.0 5.9 4.0 3.6 6.2 6.7 2.6 3.9 3.3 3.2 7.3 9.2 5.2 2.9 2.2 3.7 5.4 4.5 3.1 5.0 2.8 3.8 7.4 4.8 2.8 2.9 4.3 6.7 5.8 3.5 4.7 4.5 1.0 4.7 5.5 5.7 3.4 8.0 11.7 2.7 5.7 6.6 7.8 20.2 9.1 1.6 2.6 2.7 5.6 14.9 28.0 14.2 5.6 0.2 16.8 8.9 2.4 4.3 23.7 18.2 20.3 21.2 8.0 5.5 9.8 7.7 5.8 8.0 2.6 3.6 10.3 4.3 16.2 15.7 18.0 7.8 2.7 11.8 10.2 10.4 9.6 4.8 14.0 13.6 30.4 12.0 3.6 8.8 10.1 15.8 10.0 11.6 14.2 11.5 18.7 6.9 1.6 11.2 6.6 0.4 31.9 14.1 16.9 3.0 21.4 7.7 0.0 0.2 0.0 0.2 0.6 0.5 0.8 0.4 0.7 0.4 0.5 0.8 0.2 0.0 0.5 0.3 0.6 0.6 0.2 4.1 4.3 5.5 5.2 4.0 3.6 3.3 3.2 3.7 2.9 3.5 3.4 6.0 0.0 2.2 7.5 9.7 7.4 11.3 9.0 7.4 6.2 9.9 10.9 8.5 4.3 5.3 7.3 4.2 20.9 5.0 14.9 3.9 8.0 3.1 3.2 8.2 5.0 22.1 56.8 9.6 4.9 18.4 8.0 8.2 5.7 0.0 12.5 4.2 8.5 12.0 0.0 11.3 20.5 6.1 8.1 4.0 6.5 8.7 5.7 5.4 3.7 4.3 11.1 10.3 8.5 2.0 5.0 11.7 7.9 9.4 9.8 17.4 13.7 2.9 2.9 26.3 9.7 9.2 22.2 20.1 17.2 8.9 9.0 4.6 10.2 25.7 7.3 RCSD1 "CapZIP, MGC21854, MK2S4" ENSG00000198771 "RCSD domain containing 1" Q6JBY9 1 167630093-167708696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 115.5;skeletal muscle: 147.9" "Cell type enhanced" "Detected in many" "B-cells: 258.0;Kupffer cells: 137.5;Macrophages: 80.7;Microglial cells: 78.7;monocytes: 121.6;NK-cells: 142.2;Sertoli cells: 78.9;T-cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 195.2;HDLM-2: 91.0;REH: 224.0;RPMI-8226: 139.7;THP-1: 103.4;U-266/70: 132.0;U-698: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016597, HPA073490" Enhanced Approved "Plasma membrane" NA NA 200000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA016597: AB_2669397, HPA073490: " "unprognostic (2.13e-2)" "unprognostic (7.38e-3)" "unprognostic (6.50e-3)" "unprognostic (1.37e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.97e-4)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (3.65e-1)" "unprognostic (8.48e-2)" "unprognostic (1.01e-1)" "unprognostic (6.33e-2)" "unprognostic (2.53e-3)" "unprognostic (3.19e-1)" "unprognostic (3.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.97e-2)" 14.2 5.8 5.5 42.9 6.1 55.7 11.6 5.8 6.3 5.6 5.9 12.0 8.8 4.6 2.5 8.6 4.0 11.7 25.6 5.2 6.3 5.2 8.0 16.8 88.7 9.9 7.3 2.8 1.5 2.4 2.0 17.5 8.4 3.7 11.9 0.6 4.7 3.9 147.9 2.8 29.3 8.6 6.8 52.4 12.4 3.7 7.7 115.5 6.1 50.6 73.7 14.0 3.4 10.0 0.3 0.0 0.2 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 195.2 0.6 0.2 0.0 0.2 0.0 0.0 0.0 91.0 0.3 1.6 0.1 0.1 0.2 34.4 3.7 0.5 0.3 0.4 0.0 0.0 0.0 76.0 67.8 56.7 25.4 0.0 69.3 49.8 1.7 0.0 0.0 224.0 0.8 139.7 0.0 0.1 0.1 0.1 0.2 0.6 0.1 2.7 0.1 103.4 0.5 0.2 0.6 0.2 0.4 132.0 42.5 132.0 0.1 64.6 0.0 249.3 170.3 271.3 63.5 119.8 76.9 216.4 81.7 80.0 103.4 201.7 68.1 64.7 165.7 130.0 122.7 54.3 129.4 148.9 5.5 6.1 5.8 6.3 5.2 6.3 9.9 7.3 8.4 6.8 7.7 10.0 18.7 3.2 6.7 0.3 258.0 1.1 1.2 0.0 3.4 0.7 6.2 10.7 46.8 0.0 3.1 1.8 0.0 0.5 73.9 0.1 0.0 0.2 0.8 0.4 2.1 18.8 0.0 30.1 4.2 0.0 0.5 12.4 4.1 0.3 13.9 0.2 19.2 1.5 44.2 0.0 0.7 0.0 0.0 137.5 26.9 1.7 0.9 80.7 5.4 78.7 121.6 0.2 142.2 2.0 0.6 0.1 0.0 0.4 55.1 0.8 0.0 0.5 0.0 0.8 78.9 5.8 39.7 0.0 0.3 1.0 1.7 1.2 97.2 0.6 0.1 0.3 RD3L "TDRD9-AS1, TDRD9AS1" ENSG00000227729 "Retinal degeneration 3 like" P0DJH9 14 103940426-103942561 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 26 "heart muscle: 23.3;retina: 13.3" "Group enriched" "Detected in some" 9 "Bipolar cells: 78.5;Cardiomyocytes: 40.8;Cone photoreceptor cells: 29.2;Horizontal cells: 26.9;Rod photoreceptor cells: 19.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "olfactory bulb: 10.4" "Low region specificity" "Detected in all" HPA067971 Enhanced Approved "Cell Junctions" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "HPA067971: AB_2685935" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 78.5 0.0 0.0 40.8 0.0 0.0 0.0 29.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 REPS1 ENSG00000135597 "RALBP1 associated Eps domain containing 1" Q96D71 6 138903493-138988261 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 207.3;Excitatory neurons: 114.3;Inhibitory neurons: 138.1;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029961, HPA029962" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane, Cytosol" "HPA029961: AB_10603233, HPA029962: AB_2673269" "unprognostic (1.72e-3)" "unprognostic (9.61e-2)" "unprognostic (5.82e-3)" "unprognostic (2.77e-2)" "unprognostic (6.30e-3)" "unprognostic (1.90e-1)" "prognostic unfavorable (9.47e-4)" "unprognostic (3.79e-1)" "unprognostic (2.49e-1)" "unprognostic (9.71e-3)" "unprognostic (4.29e-3)" "unprognostic (4.42e-2)" "unprognostic (2.69e-1)" "unprognostic (1.51e-1)" "unprognostic (1.27e-1)" "unprognostic (3.83e-2)" "unprognostic (2.69e-2)" 13.5 11.9 24.7 14.9 25.4 23.2 23.6 27.7 36.8 19.2 14.8 17.4 15.4 21.9 40.2 28.0 18.4 14.0 23.9 27.4 24.0 17.4 31.3 15.2 19.4 25.2 23.9 21.1 18.8 41.0 31.7 17.2 21.3 15.9 17.3 38.8 26.1 16.2 17.5 30.0 16.4 19.5 21.5 22.1 18.1 35.6 25.9 36.0 17.8 12.6 22.2 19.5 20.1 25.3 29.3 22.6 42.3 53.1 23.4 41.6 46.2 27.8 30.7 31.9 38.2 54.1 24.8 35.2 22.9 38.9 38.0 33.6 48.7 42.0 42.1 37.6 41.9 29.6 12.9 32.9 35.3 94.6 45.9 34.1 33.7 58.6 70.3 30.2 33.5 51.2 40.2 35.1 41.4 49.4 53.9 51.3 40.4 37.4 21.3 62.4 26.0 20.0 26.5 43.6 37.7 37.2 25.7 38.7 38.0 62.0 18.6 64.4 32.9 17.8 29.6 48.5 38.8 34.4 33.7 49.2 21.1 38.3 26.4 5.9 1.3 1.9 2.2 4.0 3.8 3.0 2.9 3.2 1.9 1.6 2.9 3.6 0.7 2.9 4.5 3.5 3.3 1.2 24.7 25.4 27.7 36.8 27.4 24.0 25.2 23.9 21.3 21.5 25.9 25.3 11.8 19.2 7.4 207.3 18.0 13.4 11.7 7.9 22.2 12.6 13.7 9.5 28.4 10.0 12.2 5.5 16.7 25.6 18.9 11.9 7.9 7.8 13.7 17.5 9.7 10.3 6.0 5.0 114.3 7.1 28.3 11.5 16.3 23.3 15.9 14.4 15.7 43.8 13.3 13.5 138.1 12.8 6.1 24.0 10.3 7.7 7.2 17.2 5.4 47.8 10.5 36.8 15.5 99.5 71.2 8.9 14.7 8.6 23.9 11.2 13.5 8.6 16.5 14.4 19.7 16.8 10.9 41.7 33.8 26.4 14.9 28.6 18.7 7.6 15.2 18.1 RET "CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET51" ENSG00000165731 "Ret proto-oncogene" P07949 10 43077064-43130351 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Hirschsprung disease, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "adrenal gland: 20.8;brain: 27.3;parathyroid gland: 31.8" "Group enriched" "Detected in some" 4 "Horizontal cells: 79.1;Ionocytes: 26.4;Skeletal myocytes: 23.1" "Cancer enhanced" "Detected in many" "breast cancer: 11.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 74.6;NB-4: 42.2;SH-SY5Y: 329.3;THP-1: 95.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "midbrain: 53.3;spinal cord: 19.4" "CAB002581, HPA008356, HPA008495" Approved Supported Approved "Golgi apparatus,Plasma membrane,Cytosol" No NA 2100000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB002581: AB_563673, HPA008356: AB_1847232, HPA008495: " "unprognostic (7.94e-2)" "unprognostic (3.68e-2)" "unprognostic (4.49e-1)" "prognostic unfavorable (5.02e-4)" "unprognostic (1.15e-1)" "unprognostic (9.13e-4)" "unprognostic (1.27e-2)" "unprognostic (3.62e-2)" "unprognostic (2.86e-1)" "unprognostic (2.01e-1)" "unprognostic (1.54e-3)" "unprognostic (4.43e-1)" "unprognostic (9.35e-5)" "unprognostic (1.64e-3)" "unprognostic (8.28e-2)" "unprognostic (3.67e-3)" "unprognostic (2.02e-2)" 1.8 20.8 1.0 1.3 0.9 0.4 1.1 5.1 5.6 1.0 0.2 3.4 1.4 0.6 0.3 0.4 0.5 0.6 2.2 0.3 5.5 0.9 3.0 0.4 0.6 14.4 27.3 0.4 1.3 31.8 5.3 0.5 12.0 1.8 1.4 4.7 5.1 2.0 5.9 0.9 1.4 1.0 4.8 0.2 2.2 2.7 7.6 1.6 0.8 3.1 0.2 0.6 1.4 5.8 0.1 0.4 0.1 1.7 0.0 0.0 0.1 0.7 0.2 0.4 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 7.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 42.2 7.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.7 329.3 0.1 0.0 0.1 0.5 4.1 95.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.9 0.7 0.1 0.0 1.0 0.9 5.1 5.6 0.3 5.5 14.4 27.3 12.0 4.8 7.6 5.8 0.4 0.0 0.5 1.6 0.0 0.3 0.8 0.0 0.0 1.7 6.0 0.5 2.1 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.0 0.0 1.5 0.0 0.3 1.1 0.0 0.0 4.2 0.2 2.3 6.8 0.0 0.0 1.3 0.5 0.0 1.2 0.1 79.1 8.6 1.9 26.4 0.0 0.6 1.5 0.3 0.5 0.0 1.0 0.0 0.8 0.0 1.0 0.6 0.0 0.0 0.0 0.0 0.9 0.0 0.1 0.8 1.7 0.0 23.1 1.2 1.1 4.7 0.0 0.6 0.0 0.2 0.3 0.2 0.1 RFLNB "Cfm1, FAM101B, MGC45871, RefilinB" ENSG00000183688 "Refilin B" Q8N5W9 17 439978-445939 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 77.9" "Cell type enhanced" "Detected in many" "Adipocytes: 101.3;Endothelial cells: 51.1;Hofbauer cells: 38.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 201.5" "Lineage enriched" "Detected in many" 21 "granulocytes: 201.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 95.5;HMC-1: 222.1;NB-4: 74.8;U-937: 64.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030879, HPA060388" Enhanced Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Actin filaments" "Plasma membrane, Cytosol" "HPA030879: AB_2673643, HPA060388: AB_2732649" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (3.14e-1)" "unprognostic (3.52e-2)" "unprognostic (2.34e-1)" "unprognostic (1.31e-1)" "unprognostic (1.48e-1)" "unprognostic (1.94e-1)" "unprognostic (2.87e-2)" "unprognostic (2.48e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (3.45e-2)" "unprognostic (9.22e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-3)" 19.8 5.9 2.4 7.4 2.5 77.9 15.6 2.3 2.8 8.7 10.1 13.7 3.2 10.1 3.5 3.1 7.1 4.6 12.8 3.3 2.2 8.6 3.5 13.3 5.4 2.5 2.4 5.7 3.5 3.9 4.3 10.4 2.2 9.5 1.9 1.5 4.1 2.8 7.9 6.3 9.6 6.1 2.7 10.5 8.6 3.7 2.4 16.7 8.2 3.9 4.8 11.8 5.4 2.1 30.5 8.0 4.0 18.9 13.0 9.4 20.8 48.8 21.4 15.8 7.7 0.5 1.1 0.0 1.2 95.5 7.0 3.0 11.2 1.1 14.5 0.2 6.5 1.3 1.5 2.2 19.0 11.4 222.1 5.2 0.3 5.0 1.9 6.1 16.0 4.8 4.7 0.3 18.1 0.4 0.6 74.8 8.6 0.8 0.3 3.2 8.6 0.0 2.9 0.1 0.3 43.6 19.8 0.0 17.6 14.9 0.4 34.7 3.2 12.4 11.0 7.5 0.1 7.1 7.7 0.0 0.2 64.1 19.5 201.5 6.9 80.7 6.1 5.4 6.2 0.1 6.1 5.2 2.1 0.1 9.7 8.7 35.5 2.2 7.3 9.1 4.3 3.8 2.4 2.5 2.3 2.8 3.3 2.2 2.5 2.4 2.2 2.7 2.4 2.1 101.3 0.0 4.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 3.1 7.4 0.0 0.0 1.8 1.8 0.0 0.8 16.5 0.0 0.0 1.1 0.0 2.3 1.9 51.1 0.0 0.0 0.0 0.9 1.2 9.2 0.0 6.0 1.3 12.5 0.0 0.0 38.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 1.9 0.0 0.0 5.9 0.0 0.0 0.5 1.5 0.0 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.5 10.7 4.2 0.0 0.0 RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;retina: 3.0" "Group enriched" "Detected in some" 7 "Early spermatids: 9.1;Hepatic stellate cells: 8.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.5;HMC-1: 2.7;Karpas-707: 3.0;SH-SY5Y: 3.7;SiHa: 1.8;THP-1: 3.5" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (4.54e-1)" "unprognostic (6.63e-8)" "unprognostic (3.14e-3)" "unprognostic (1.89e-1)" 0.1 2.9 2.5 0.2 2.3 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.3 0.1 0.0 1.3 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.5 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.1 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 2.5 2.3 0.0 10.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.4 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 10.2;prostate: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 17.6;Inhibitory neurons: 8.6" "Cancer enriched" "Detected in single" 15 "prostate cancer: 5.6" "Region enriched" "Detected in many" 4 "cerebral cortex: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (3.81e-2)" "unprognostic (4.05e-2)" "unprognostic (8.29e-2)" "unprognostic (9.66e-3)" "unprognostic (2.54e-1)" "unprognostic (9.90e-2)" "unprognostic (2.59e-1)" "unprognostic (6.02e-3)" "unprognostic (2.22e-2)" "unprognostic (3.44e-2)" "unprognostic (8.64e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.04e-4)" "unprognostic (6.02e-2)" "unprognostic (3.28e-2)" "unprognostic (5.62e-7)" "unprognostic (3.50e-2)" 0.0 0.5 1.5 0.0 1.9 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 0.0 0.1 1.7 0.7 0.3 0.0 0.0 0.1 0.0 1.7 3.8 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 10.2 2.3 0.9 1.7 0.7 1.7 0.0 1.0 1.6 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.7 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 24.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Spermatocytes: 2.0;Spermatogonia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.6;NB-4: 2.2;U-266/70: 2.5;U-266/84: 2.6" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (1.63e-1)" "unprognostic (9.90e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.25e-2)" "unprognostic (4.31e-2)" "unprognostic (1.90e-1)" "unprognostic (6.32e-2)" 0.1 0.1 0.0 0.2 0.1 1.4 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.5 0.7 0.0 0.1 0.1 0.1 0.3 0.0 2.4 0.5 0.0 0.5 1.3 0.3 0.0 0.0 0.7 0.1 24.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 1.0 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.8 0.0 0.4 0.6 2.2 0.1 0.1 0.0 1.1 0.2 0.3 0.0 0.2 0.8 0.1 0.0 0.2 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 2.5 2.6 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (2.10e-1)" "unprognostic (3.22e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.09e-4)" "unprognostic (2.22e-1)" "unprognostic (5.42e-2)" "unprognostic (1.51e-3)" "unprognostic (1.81e-3)" "unprognostic (9.77e-2)" "prognostic favorable (8.55e-13)" "unprognostic (2.46e-2)" "unprognostic (1.68e-1)" "unprognostic (3.03e-3)" "unprognostic (1.18e-1)" 9.8 10.4 7.5 8.7 6.9 5.6 8.5 6.6 6.7 7.9 3.4 12.9 10.7 8.8 7.8 8.6 8.3 6.0 12.9 7.3 7.8 11.5 7.4 9.1 7.5 5.8 6.3 10.1 10.7 19.1 10.5 9.3 6.0 8.7 13.4 7.8 11.0 11.4 17.3 9.4 11.6 9.8 5.6 7.4 10.3 6.4 8.0 8.9 12.2 18.6 9.6 8.0 6.5 5.9 18.0 16.6 18.9 15.8 17.3 18.6 11.1 13.9 20.1 18.9 17.4 14.2 6.7 13.9 9.7 17.8 34.9 9.9 18.3 26.2 15.5 18.6 10.7 11.9 32.9 10.7 16.3 13.0 16.1 18.8 32.8 19.9 24.0 27.0 22.7 10.6 8.2 7.5 17.3 8.5 4.0 4.7 7.9 14.7 19.2 13.2 13.5 9.9 16.5 12.4 13.8 14.9 12.3 17.0 11.2 16.6 14.2 6.2 29.0 15.1 18.9 10.5 11.8 11.1 16.5 14.3 21.5 5.4 19.7 1.1 0.2 0.4 0.7 0.4 1.1 0.8 0.5 0.8 0.1 1.0 0.6 0.7 0.7 1.1 0.6 0.6 0.5 0.2 7.5 6.9 6.6 6.7 7.3 7.8 5.8 6.3 6.0 5.6 8.0 5.9 13.9 6.4 12.6 0.0 23.4 5.7 24.5 14.8 9.1 40.8 15.0 10.0 16.6 18.6 15.8 27.6 20.9 10.9 19.1 46.1 13.7 20.1 17.5 9.8 8.3 14.9 43.3 8.6 0.2 17.6 10.6 7.5 18.8 14.9 5.7 33.4 16.1 16.4 7.5 16.8 0.1 26.0 22.4 7.7 6.1 36.8 8.4 5.7 1.8 0.0 11.1 18.8 25.7 0.0 0.1 20.6 38.3 10.9 15.2 25.3 36.3 14.2 17.7 22.3 6.6 11.8 9.3 16.6 6.1 8.1 5.3 10.3 16.4 7.1 28.9 28.8 RGR RP44 ENSG00000148604 "Retinal G protein coupled receptor" P47804 10 84230666-84259960 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Sensory transduction, Vision" "G-protein coupled receptor, Photoreceptor protein, Receptor, Retinal protein, Transducer" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "retina: 139.0" "Cell type enriched" "Detected in some" 29 "Muller glia cells: 1475.8" "Cancer enriched" "Detected in single" 4 "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "midbrain: 23.4;olfactory bulb: 49.7;thalamus: 27.3" HPA059149 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 5: Muller glia cells - Visual perception" Vesicles "Plasma membrane, Cytosol" "HPA059149: " "unprognostic (9.28e-2)" "unprognostic (1.05e-1)" "unprognostic (1.37e-1)" "unprognostic (9.53e-2)" "unprognostic (4.57e-2)" "unprognostic (1.57e-1)" "unprognostic (1.59e-1)" "unprognostic (1.97e-1)" 0.2 0.0 11.9 0.0 11.9 0.0 0.1 4.4 14.6 0.0 14.4 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.5 7.4 8.5 0.0 0.0 0.2 0.0 5.2 8.2 0.0 0.0 0.0 0.4 0.0 5.4 0.0 0.0 139.0 0.1 0.0 0.0 0.1 0.1 0.0 3.1 0.0 0.2 0.9 10.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 11.9 4.4 14.6 7.4 8.5 5.2 8.2 5.4 3.1 10.1 6.2 0.0 0.0 0.0 6.8 0.0 0.0 0.1 0.0 0.0 20.6 0.1 0.1 0.4 0.0 0.0 0.0 31.3 0.0 0.0 0.1 0.0 0.0 8.6 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.3 0.1 0.0 0.0 0.0 0.0 10.6 0.3 0.0 0.0 0.0 0.0 1475.8 0.0 2.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.6 0.0 2.8 0.0 0.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 222.9" "Cell type enhanced" "Detected in many" "granulocytes: 291.2;Hofbauer cells: 528.1;Kupffer cells: 297.2;Langerhans cells: 358.3;Macrophages: 529.3;monocytes: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 474.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004559, HPA021305, HPA058485" Enhanced Supported Supported "Nucleoplasm,Plasma membrane" NA NA 840000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004559: AB_628216, HPA021305: AB_1856225, HPA058485: AB_2683732" "unprognostic (1.64e-2)" "prognostic favorable (6.81e-4)" "unprognostic (7.98e-2)" "prognostic favorable (6.32e-4)" "unprognostic (5.21e-2)" "unprognostic (6.19e-2)" "unprognostic (4.32e-3)" "unprognostic (6.35e-2)" "unprognostic (9.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.20e-10)" "unprognostic (2.50e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (7.92e-3)" 25.1 20.6 20.0 59.3 20.2 74.5 40.7 22.3 30.4 63.9 22.3 114.3 34.2 38.5 15.8 51.5 28.5 38.3 13.4 20.7 24.5 18.8 11.4 28.1 119.0 28.6 24.5 22.5 7.0 6.9 13.8 45.6 28.9 43.2 49.7 2.6 41.0 20.3 31.5 22.9 58.3 42.8 26.1 48.7 30.0 4.9 26.1 222.9 33.0 11.6 96.5 50.3 45.8 37.2 165.2 31.2 2.4 294.7 41.4 262.6 25.9 74.9 118.1 45.3 73.5 9.8 38.7 66.8 38.1 60.9 45.7 35.4 44.3 48.2 123.8 32.0 42.8 183.1 8.9 24.2 63.1 40.0 474.0 100.7 63.1 88.3 84.4 159.4 88.2 65.4 47.6 58.5 55.0 79.2 221.9 134.8 13.5 21.2 71.1 43.8 0.3 26.1 24.7 40.4 10.8 9.3 14.4 192.6 285.3 36.3 35.1 71.7 108.3 25.4 21.9 36.1 67.8 2.7 46.0 27.0 7.6 166.5 11.4 184.8 116.0 1.4 77.9 151.4 82.9 36.0 169.6 134.9 224.3 21.7 397.5 303.3 52.5 44.3 130.4 133.2 202.3 372.5 20.0 20.2 22.3 30.4 20.7 24.5 28.6 24.5 28.9 26.1 26.1 37.2 10.4 0.0 13.1 2.6 60.3 36.8 25.7 104.5 27.9 0.2 68.9 96.6 1.1 1.5 39.7 1.8 0.0 14.0 70.1 7.1 60.7 0.8 2.1 89.8 25.1 12.7 18.7 156.6 0.2 6.4 34.8 68.6 11.2 53.6 291.2 101.2 13.2 1.5 528.1 0.0 1.8 85.7 32.6 297.2 358.3 5.1 50.1 529.3 94.3 67.5 294.5 1.8 50.4 0.5 0.2 9.9 10.0 9.4 32.1 88.8 3.3 5.2 24.6 0.8 13.1 14.4 31.8 0.3 9.3 39.6 28.1 10.1 164.7 3.5 19.3 41.4 RGS14 ENSG00000169220 "Regulator of G protein signaling 14" O43566 5 177357924-177372596 "Predicted intracellular proteins" "Cell cycle, Cell division" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 110.4" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 72.8;Proximal tubular cells: 113.7;Squamous epithelial cells: 95.8;Suprabasal keratinocytes: 115.1" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 110.4;cerebral cortex: 67.9;hippocampal formation: 56.4" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 112.5;HMC-1: 95.4;NB-4: 44.8;RPMI-8226: 57.9" "Group enriched" "Detected in many" 10 "amygdala: 66.0;basal ganglia: 57.9;cerebral cortex: 46.8;hippocampal formation: 93.6;white matter: 23.8" "Region enhanced" "Detected in many" "basal ganglia: 102.1" "HPA046847, HPA061819" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Intermediate filaments" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Vesicles, Plasma membrane, Intermediate filaments" "HPA046847: AB_2679836, HPA061819: " "unprognostic (6.05e-3)" "unprognostic (1.65e-2)" "unprognostic (8.57e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.97e-4)" "unprognostic (7.27e-2)" "prognostic unfavorable (1.84e-6)" "unprognostic (1.95e-2)" "unprognostic (4.34e-2)" "unprognostic (2.04e-3)" "unprognostic (2.71e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" "unprognostic (3.17e-2)" "unprognostic (1.66e-1)" "unprognostic (1.17e-2)" "unprognostic (2.78e-2)" 3.5 2.8 16.0 13.9 110.4 22.4 2.9 0.0 67.9 3.1 1.8 3.7 6.3 2.3 0.4 10.0 7.7 4.3 1.3 56.4 4.5 8.5 28.7 5.5 18.1 0.0 0.4 1.1 3.7 1.5 2.4 1.4 0.1 3.5 0.9 0.0 6.2 2.1 2.6 6.1 11.0 1.8 0.1 27.7 4.9 1.9 15.2 16.3 6.1 0.9 6.6 4.1 5.0 3.2 5.4 1.1 2.3 1.4 0.1 0.0 3.7 0.2 0.0 0.5 0.6 3.7 10.4 13.3 7.3 0.4 1.3 10.6 0.2 3.8 0.0 112.5 0.5 20.7 1.0 4.7 0.9 16.3 95.4 1.8 1.1 0.6 0.7 1.4 0.6 14.9 3.5 26.5 0.2 0.4 21.7 44.8 1.7 5.4 2.8 10.2 0.3 57.9 1.5 1.6 0.4 1.9 0.4 0.4 8.8 0.0 3.5 25.2 1.1 0.2 1.9 0.0 9.7 13.9 7.1 5.8 1.6 30.3 2.4 70.6 39.9 148.8 62.4 37.9 63.0 27.7 57.9 57.8 39.8 26.6 47.4 43.1 140.0 23.6 41.2 17.6 60.9 43.9 16.0 110.4 0.0 67.9 56.4 4.5 0.0 0.4 0.1 0.1 15.2 3.2 5.3 6.4 4.4 2.6 27.3 68.8 23.9 15.4 72.8 0.7 8.9 11.8 2.3 37.1 5.6 11.0 2.1 3.9 41.4 4.2 31.3 11.4 0.6 19.5 2.0 6.5 4.8 7.4 4.6 16.7 10.4 5.4 12.2 8.1 24.7 2.8 8.2 64.0 26.1 0.0 1.5 10.0 10.2 17.0 23.3 1.5 2.8 18.2 21.4 6.5 18.1 9.9 48.4 0.5 0.3 12.8 17.2 2.2 18.0 14.1 16.8 113.7 11.7 2.0 0.0 1.6 4.6 0.1 20.3 95.8 115.1 3.3 51.2 1.1 4.4 20.0 RGS19 "GAIP, RGSGAIP" ENSG00000171700 "Regulator of G protein signaling 19" P49795 20 64073181-64079988 "Predicted intracellular proteins" Autophagy "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 57.2;lymphoid tissue: 77.5" "Cell type enhanced" "Detected in many" "B-cells: 97.8;dendritic cells: 82.0;Hofbauer cells: 135.0;Kupffer cells: 104.6;Macrophages: 101.6;monocytes: 86.3;NK-cells: 140.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 154.2;NB-4: 128.1;THP-1: 107.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA056384, HPA069984" Enhanced Supported "Nucleoli fibrillar center,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Cell Junctions" "Nucleoli fibrillar center" "HPA056384: AB_2732602, HPA069984: AB_2732145" "unprognostic (3.98e-2)" "unprognostic (2.32e-1)" "unprognostic (4.26e-3)" "unprognostic (8.42e-2)" "unprognostic (2.03e-1)" "unprognostic (9.94e-2)" "prognostic unfavorable (2.75e-4)" "unprognostic (1.25e-2)" "unprognostic (2.41e-2)" "unprognostic (3.91e-1)" "unprognostic (3.22e-1)" "unprognostic (2.88e-1)" "prognostic unfavorable (2.06e-9)" "unprognostic (1.35e-1)" "unprognostic (2.68e-2)" "unprognostic (6.77e-2)" "unprognostic (4.66e-3)" 12.5 8.8 7.1 28.5 6.8 57.2 9.0 7.3 7.8 5.9 6.3 6.7 7.5 5.1 2.0 8.1 6.9 6.0 6.4 6.7 7.3 7.6 5.9 19.6 35.2 12.3 8.8 2.3 7.0 2.7 4.3 7.2 10.0 7.3 2.2 0.3 8.5 2.5 2.5 8.4 21.1 4.3 11.4 77.5 8.2 1.8 11.8 13.9 6.8 2.2 17.3 8.3 6.9 12.2 16.1 24.1 6.8 12.2 3.0 4.9 11.5 10.0 6.9 20.2 8.4 36.0 21.8 28.1 27.0 6.2 21.6 15.4 7.0 12.8 4.8 14.0 13.2 40.3 12.3 14.8 4.0 83.0 154.2 3.3 7.7 8.6 3.0 4.0 13.3 18.4 15.5 14.5 6.2 28.6 61.6 128.1 7.0 13.8 30.3 51.1 4.0 20.4 5.7 7.8 12.9 12.1 10.3 6.3 13.6 3.4 8.3 107.3 14.0 18.9 9.5 3.3 9.8 9.1 7.6 34.7 10.5 62.6 12.8 289.5 273.2 760.9 96.6 396.0 99.2 125.7 91.1 92.6 228.8 125.7 62.4 64.9 606.5 75.1 458.3 130.8 107.1 204.7 7.1 6.8 7.3 7.8 6.7 7.3 12.3 8.8 10.0 11.4 11.8 12.2 19.0 3.2 4.1 2.0 97.8 9.7 6.4 8.0 4.0 0.1 10.4 13.3 3.9 2.8 5.7 1.8 0.0 3.0 82.0 0.5 0.0 12.0 0.5 2.8 8.3 17.2 0.0 14.7 1.4 14.3 8.1 6.5 4.6 2.2 48.8 4.5 15.0 0.8 135.0 0.0 1.0 0.5 4.1 104.6 50.0 1.1 4.4 101.6 5.4 17.8 86.3 0.3 140.1 2.5 0.2 16.9 3.8 1.2 25.0 14.5 0.1 2.4 3.3 0.2 13.1 2.4 8.8 0.3 7.0 5.2 8.9 1.8 57.1 3.7 0.9 8.8 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RGS7BP R7BP ENSG00000186479 "Regulator of G protein signaling 7 binding protein" Q6MZT1 5 64506015-64612319 "Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.0" "Group enriched" "Detected in some" 5 "Excitatory neurons: 122.5;Inhibitory neurons: 170.6;Oligodendrocyte precursor cells: 67.8" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 26.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HUVEC TERT2: 11.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039600 Approved Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Actin filaments" "HPA039600: AB_2676591" "unprognostic (2.93e-1)" "unprognostic (3.39e-1)" "unprognostic (7.35e-2)" "unprognostic (4.77e-2)" "unprognostic (7.57e-2)" "unprognostic (8.59e-2)" "unprognostic (5.22e-2)" "unprognostic (8.81e-3)" "unprognostic (1.86e-2)" "unprognostic (7.64e-2)" "unprognostic (5.49e-3)" "unprognostic (1.83e-1)" "unprognostic (1.65e-3)" "unprognostic (3.39e-3)" "unprognostic (2.06e-3)" "unprognostic (6.46e-2)" "unprognostic (8.50e-3)" 1.9 3.2 3.2 0.5 12.2 0.0 0.5 1.0 26.0 4.0 0.0 0.6 0.9 2.3 3.7 1.7 7.8 1.7 2.6 7.2 1.2 2.0 1.0 1.4 0.3 0.2 3.3 2.4 0.2 0.1 0.8 0.0 0.0 5.3 0.7 4.8 1.8 7.4 0.1 0.3 1.0 1.4 0.0 0.7 0.8 0.8 10.2 0.0 0.3 1.0 0.1 0.9 0.5 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 12.2 1.0 26.0 7.2 1.2 0.2 3.3 0.0 0.0 10.2 5.0 0.4 0.0 0.0 5.5 0.1 0.0 0.1 0.1 0.6 6.5 0.7 1.1 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 5.1 4.6 0.0 2.7 122.5 0.0 0.0 0.8 0.0 4.7 0.0 0.1 23.2 0.1 0.0 0.0 170.6 0.0 0.0 0.3 0.0 1.9 7.2 0.1 0.0 12.2 0.0 3.6 0.0 67.8 6.4 0.0 0.0 13.9 0.0 0.1 0.0 0.2 2.2 2.1 6.6 0.1 13.2 0.3 0.6 0.4 0.0 0.0 0.2 0.0 0.0 0.2 RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 28.9;retina: 17.4;skeletal muscle: 9.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 29.0;Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.3;HMC-1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" 0.0 0.1 0.8 0.0 0.7 0.0 0.0 0.8 0.8 0.0 28.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.3 3.3 0.9 0.3 0.0 0.3 0.0 1.1 1.4 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 17.4 0.1 0.1 9.0 0.1 0.0 0.0 0.5 0.0 0.1 0.4 1.5 0.1 0.0 3.2 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.1 6.3 0.1 0.0 0.1 0.1 1.6 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.8 0.1 0.2 0.0 1.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.3 0.0 0.2 0.3 0.1 0.1 0.3 0.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.8 0.8 3.3 0.9 1.1 1.4 0.9 0.5 1.5 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 29.0 0.4 0.4 4.6 0.0 0.0 1.8 56.3 0.3 0.6 0.5 0.0 0.0 5.1 0.2 0.1 0.7 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.8 0.7 0.0 0.2 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.4 0.9 0.0 75.4 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.1 1.1 0.4 0.0 RHCE "CD240CE, RH" ENSG00000188672 "Rh blood group CcEe antigens" P18577 1 25362249-25430192 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 48.5" "Cell type enriched" "Detected in some" 67 "Erythroid cells: 511.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HEL: 81.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (1.37e-1)" "unprognostic (3.53e-1)" "unprognostic (2.38e-1)" "unprognostic (6.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.12e-2)" "unprognostic (3.81e-2)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "unprognostic (4.61e-2)" "unprognostic (5.77e-5)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" "unprognostic (7.15e-3)" "unprognostic (1.63e-1)" 0.3 0.6 1.5 0.1 1.9 48.5 0.3 1.6 3.3 0.3 1.2 0.2 0.2 0.2 4.2 0.6 1.0 0.3 1.2 1.5 1.4 0.4 1.7 0.4 0.5 1.9 1.6 0.5 1.2 0.1 3.4 1.1 1.9 1.0 0.3 2.2 5.5 0.2 1.5 0.6 0.1 0.0 1.5 1.1 0.4 2.2 1.6 0.8 0.6 0.9 0.3 0.1 0.5 2.2 0.2 0.1 0.2 0.5 0.9 0.6 0.1 0.3 0.3 0.4 0.1 0.1 1.5 0.7 1.1 1.0 0.1 0.3 0.0 0.2 0.2 0.4 0.1 81.3 0.0 0.0 1.1 0.0 0.6 1.9 1.5 0.6 0.5 0.0 0.0 0.6 17.5 0.4 0.5 0.8 0.0 0.6 1.7 0.7 0.5 0.2 0.2 2.6 0.0 0.0 0.7 0.8 0.3 0.3 1.0 0.8 0.5 0.0 0.1 0.2 0.0 0.9 0.0 5.1 1.4 1.0 2.9 0.9 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 1.9 1.6 3.3 1.5 1.4 1.9 1.6 1.9 1.5 1.6 2.2 0.8 0.0 0.0 5.5 0.8 0.5 0.5 0.3 0.6 4.2 1.1 2.5 0.7 1.5 0.2 0.0 0.0 0.8 1.2 0.5 0.0 0.3 1.1 1.2 0.7 0.4 0.0 511.8 2.9 0.2 0.7 0.4 3.6 0.8 4.5 0.6 0.0 0.7 0.2 6.7 2.3 0.0 0.0 0.6 0.4 0.5 0.6 1.7 0.0 0.0 0.0 4.7 1.0 2.0 2.7 0.5 0.0 0.7 3.0 0.3 0.1 0.0 0.9 2.4 6.6 0.5 0.5 3.0 7.6 0.6 1.4 0.8 0.8 0.7 0.3 0.7 RHD "CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI" ENSG00000187010 "Rh blood group D antigen" Q02161 1 25272393-25330445 "Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 15.8" "Cell type enriched" "Detected in some" 21 "Erythroid cells: 153.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 6.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.3" "Group enriched" "Detected in some" 7 "HEL: 43.0;K-562: 13.0" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (4.75e-3)" "unprognostic (7.70e-2)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.09e-2)" "unprognostic (4.84e-2)" "unprognostic (1.11e-2)" "unprognostic (5.25e-2)" "unprognostic (1.11e-2)" "unprognostic (1.91e-1)" "unprognostic (1.27e-2)" "unprognostic (1.89e-1)" "unprognostic (4.96e-3)" "unprognostic (1.93e-1)" "unprognostic (8.09e-2)" "unprognostic (5.53e-2)" "unprognostic (4.92e-3)" 0.1 0.4 0.4 0.5 1.0 15.8 0.1 1.4 0.7 0.3 0.1 0.1 0.3 0.4 0.1 0.3 0.2 0.4 0.3 0.4 0.1 0.1 0.1 0.2 0.7 0.3 0.1 0.5 0.4 0.0 0.2 0.3 0.2 0.3 0.1 1.9 2.4 0.0 3.8 2.0 0.3 0.0 0.0 0.6 0.2 0.5 0.5 0.1 0.3 0.0 0.1 0.1 0.1 1.2 0.2 0.0 0.3 0.3 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.3 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.2 43.0 1.0 0.2 0.0 0.3 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.2 13.0 0.9 0.1 0.2 0.2 0.3 4.0 0.0 0.2 0.3 0.2 0.1 0.0 0.1 0.6 0.4 0.1 0.2 0.1 0.1 0.2 0.6 0.4 0.7 0.2 0.5 0.2 0.4 0.2 0.2 0.6 0.2 0.2 4.3 0.9 2.0 0.6 0.4 0.7 1.0 0.8 0.5 0.1 1.3 0.9 0.8 6.3 1.0 0.6 0.4 0.7 0.6 0.4 1.0 1.4 0.7 0.4 0.1 0.3 0.1 0.2 0.0 0.5 1.2 0.2 0.0 0.5 1.0 0.6 0.1 0.2 0.0 0.0 0.3 0.1 0.1 1.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.3 1.0 0.0 153.0 5.2 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.4 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.0 0.0 3.0 0.0 3.7 0.0 0.4 0.0 7.1 6.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 1.2 0.4 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.0 0.1 RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.4" "Group enriched" "Detected in some" 14 "Endometrial ciliated cells: 202.9;Glandular and luminal cells: 337.5;granulocytes: 334.3" "Group enriched" "Detected in many" 5 "endometrial cancer: 42.8;ovarian cancer: 41.1;renal cancer: 27.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1312.1" "Lineage enriched" "Detected in single" 1544 "granulocytes: 1312.1" "Cell line enriched" "Detected in some" 5 "HMC-1: 1562.9" "Low region specificity" "Detected in all" HPA037859 Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA037859: AB_10697084" "unprognostic (9.26e-3)" "unprognostic (1.91e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-2)" "unprognostic (2.06e-2)" "unprognostic (5.27e-3)" "unprognostic (9.55e-2)" "unprognostic (3.04e-3)" "unprognostic (2.36e-1)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (7.20e-3)" "unprognostic (1.89e-2)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (3.77e-2)" "unprognostic (2.80e-3)" 4.1 0.4 0.0 2.9 0.0 1.3 4.7 0.0 0.0 24.4 0.0 7.5 3.3 12.8 16.3 7.7 5.3 16.3 0.9 0.0 0.0 14.3 0.9 10.7 4.1 0.0 0.0 0.2 1.4 0.3 0.4 0.6 0.0 2.8 7.4 0.0 2.8 20.0 1.0 4.5 6.7 7.3 0.0 3.0 6.4 1.0 0.1 3.1 2.0 2.5 4.6 7.7 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 143.8 0.0 0.9 0.0 75.2 1562.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 5.9 330.8 0.0 0.0 0.0 0.1 0.2 0.7 20.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.5 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.6 0.9 1.1 0.8 1312.1 0.0 8.6 0.0 0.1 0.1 0.5 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.0 0.2 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 20.2 0.0 2.3 0.7 0.0 1.9 3.6 0.0 202.9 17.6 1.3 0.0 0.0 0.0 0.2 0.2 0.4 0.0 337.5 334.3 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 50.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 64.1;Alveolar cells type 2: 77.7;Excitatory neurons: 33.3;Proximal enterocytes: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 85.7;hTCEpi: 73.6;RT4: 126.9" "Low region specificity" "Detected in all" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA060938: AB_2684391" "unprognostic (2.67e-3)" "unprognostic (1.64e-1)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (7.83e-3)" "unprognostic (2.13e-2)" "unprognostic (8.13e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-3)" "unprognostic (1.93e-2)" "unprognostic (1.60e-2)" "unprognostic (1.46e-2)" "prognostic favorable (2.98e-4)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.43e-1)" 6.5 8.8 17.9 7.5 31.7 2.3 8.4 3.6 27.6 6.8 7.1 6.2 8.5 7.7 5.3 4.8 9.8 6.5 21.8 21.4 7.3 11.2 2.4 50.5 14.9 4.2 10.3 25.8 8.0 9.6 14.2 11.2 4.1 7.7 2.5 5.6 6.4 23.0 16.5 5.5 21.2 6.5 0.8 12.6 8.3 8.1 22.8 8.9 18.5 13.6 16.7 10.4 4.5 15.1 6.8 13.2 10.4 16.7 12.4 8.7 14.0 9.2 12.0 14.2 10.7 34.2 6.6 85.7 13.8 13.3 18.5 13.2 5.0 51.5 6.8 7.4 3.0 9.3 17.8 9.7 6.0 5.5 18.5 11.3 73.6 14.8 7.4 9.8 10.4 6.1 2.3 8.2 9.5 19.7 3.5 8.8 11.0 19.7 9.2 4.7 16.8 5.9 10.1 126.9 6.8 12.5 7.1 21.2 14.5 7.7 4.0 14.0 12.8 17.7 12.8 32.0 10.6 20.7 21.5 30.2 17.2 7.9 14.0 2.9 0.6 0.8 1.7 1.0 1.1 5.1 0.4 0.8 0.6 4.3 0.6 0.6 0.1 2.9 1.1 1.8 0.9 0.8 17.9 31.7 3.6 27.6 21.4 7.3 4.2 10.3 4.1 0.8 22.8 15.1 4.1 64.1 77.7 13.1 7.6 2.9 2.5 5.2 2.8 31.1 2.9 3.2 10.2 5.7 9.1 7.3 4.2 14.7 4.5 0.2 1.9 2.1 0.8 1.9 4.8 6.2 6.0 1.3 33.3 3.7 8.5 5.5 6.1 3.2 4.5 2.4 7.9 1.9 14.3 16.8 13.1 5.8 0.0 2.5 2.6 0.8 6.2 3.5 1.8 5.6 1.5 7.3 8.2 7.1 1.8 4.1 2.6 6.4 4.2 1.2 57.2 6.2 3.1 6.1 0.0 7.2 4.2 0.9 1.9 0.5 0.6 5.6 2.5 2.9 2.8 0.9 RHOJ "ARHJ, FLJ14445, RASL7B, TCL" ENSG00000126785 "Ras homolog family member J" Q9H4E5 14 63204114-63293508 "Predicted intracellular proteins" Angiogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 41.0;Astrocytes: 176.0;Endothelial cells: 72.5;Hepatic stellate cells: 41.4;Microglial cells: 35.6;Oligodendrocyte precursor cells: 43.2;Skeletal myocytes: 34.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 63.8;HUVEC TERT2: 375.4;TIME: 100.9;WM-115: 106.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003050 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA003050: AB_1079812" "unprognostic (7.24e-2)" "unprognostic (1.72e-1)" "unprognostic (4.37e-2)" "unprognostic (2.42e-1)" "unprognostic (6.71e-2)" "unprognostic (1.77e-2)" "unprognostic (2.89e-1)" "unprognostic (2.33e-2)" "unprognostic (2.19e-1)" "unprognostic (3.04e-3)" "unprognostic (1.42e-2)" "unprognostic (7.07e-2)" "prognostic unfavorable (1.31e-4)" "unprognostic (3.50e-3)" "unprognostic (4.84e-2)" "unprognostic (1.86e-2)" "unprognostic (1.06e-3)" 19.6 3.3 12.5 8.5 14.6 0.1 17.4 10.8 16.9 12.9 8.5 14.2 7.5 27.9 17.3 15.5 18.5 25.3 17.9 14.0 11.1 11.7 4.2 21.5 9.6 10.9 11.0 14.2 4.4 3.5 6.4 9.3 11.0 11.8 10.7 5.5 8.4 13.8 7.9 7.6 9.8 31.4 8.3 12.6 9.3 2.8 14.5 3.1 13.8 13.4 4.9 19.7 9.4 13.0 0.0 0.0 63.8 0.0 0.0 0.0 0.0 10.6 42.6 3.6 6.2 0.0 0.0 0.0 5.9 0.8 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.1 0.3 0.0 0.1 8.0 35.8 375.4 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.0 0.4 0.0 5.1 0.0 0.4 0.0 0.1 0.1 0.0 0.0 14.6 1.1 0.1 0.0 100.9 0.1 1.1 0.8 6.1 0.0 0.0 0.0 0.0 0.0 106.5 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 12.5 14.6 10.8 16.9 14.0 11.1 10.9 11.0 11.0 8.3 14.5 13.0 41.0 0.0 1.3 176.0 0.3 5.9 0.3 0.1 0.0 0.3 1.2 5.2 3.8 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 1.4 0.5 0.3 6.7 72.5 0.0 0.0 11.1 0.9 0.0 31.0 0.0 0.3 0.0 0.5 41.4 0.5 0.1 0.0 2.2 0.0 0.0 1.9 7.7 1.6 11.8 1.0 3.6 35.6 0.0 11.1 0.0 43.2 0.4 0.1 0.0 16.1 2.5 0.6 0.0 0.0 0.0 0.4 6.6 34.6 17.0 0.1 0.4 0.9 4.8 0.1 0.6 6.9 0.0 1.4 RHOXF2 "CT107, PEPP-2, PEPP2, THG1" ENSG00000131721 "Rhox homeobox family member 2" Q9BQY4 X 120158613-120165630 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 11.0" "Group enriched" "Detected in some" 22 "Spermatocytes: 6.6;Spermatogonia: 7.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "K-562: 100.5;NB-4: 69.9;THP-1: 27.9;U-266/84: 47.2" "HPA003314, CAB020794" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB020794: , HPA003314: AB_1855193" "unprognostic (1.60e-1)" "unprognostic (5.04e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.0 11.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.5 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.5 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 2.1 0.5 0.1 0.7 0.9 0.7 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RHOXF2B ENSG00000203989 "Rhox homeobox family member 2B" P0C7M4 X 120072264-120077690 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 21.2" "Cell type enriched" "Detected in single" 6 "Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HL-60: 596.6;K-562: 903.3;NB-4: 1129.0" HPA003314 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA003314: AB_1855193" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 596.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 903.3 0.0 0.0 0.0 0.0 1129.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 94.3 3.0 0.0 0.0 0.6 0.2 0.0 156.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIC8A "synembryn, synembryn-A" ENSG00000177963 "RIC8 guanine nucleotide exchange factor A" Q9NPQ8 11 207511-215113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041491, CAB046012" Approved Approved "Plasma membrane,Cytosol" NA NA 10000 "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "CAB046012: AB_11129402, HPA041491: AB_2677510" "unprognostic (3.93e-2)" "unprognostic (8.69e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.60e-4)" "unprognostic (1.61e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.13e-3)" "unprognostic (8.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.56e-1)" "unprognostic (8.35e-2)" "unprognostic (2.63e-3)" "unprognostic (5.35e-2)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.60e-1)" 39.2 39.6 43.0 34.8 43.6 40.6 37.4 42.1 48.5 41.2 46.6 46.3 29.5 44.2 41.8 43.1 41.1 30.6 42.9 45.4 43.7 36.5 37.8 37.6 37.6 43.5 44.4 39.7 39.3 34.2 38.1 34.1 44.2 39.0 30.8 24.8 34.4 40.3 32.8 39.5 38.1 49.4 43.4 41.6 38.1 44.0 44.0 41.6 33.7 28.3 41.8 45.9 36.6 45.0 176.3 83.9 66.8 66.7 89.7 73.4 46.3 124.1 99.2 166.0 114.2 72.6 121.1 69.6 50.5 189.0 125.7 93.4 76.4 131.4 92.0 84.5 76.7 39.4 59.5 67.8 72.3 66.5 125.8 80.6 114.3 103.2 92.6 85.2 82.8 72.8 68.7 66.0 129.3 71.1 79.6 52.6 61.1 74.0 103.0 74.0 66.0 47.5 96.9 45.6 69.2 62.2 96.3 107.1 67.1 63.9 76.1 52.8 93.4 109.2 96.5 40.4 117.3 72.6 117.6 67.8 107.7 59.5 83.5 72.9 41.1 88.3 79.0 49.7 78.2 64.4 70.1 69.0 43.7 55.1 59.9 60.6 59.9 73.0 61.0 35.8 65.0 86.6 43.0 43.6 42.1 48.5 45.4 43.7 43.5 44.4 44.2 43.4 44.0 45.0 30.9 16.0 21.1 10.7 28.7 17.7 20.5 38.6 17.1 28.1 22.5 27.2 23.5 28.6 25.5 25.8 10.4 41.4 46.5 26.3 27.4 53.1 20.2 15.9 24.3 27.2 20.3 27.4 9.4 44.2 60.0 30.4 23.0 19.7 17.7 28.8 27.8 17.1 46.8 32.0 8.4 19.2 30.5 27.4 11.5 17.3 30.7 27.5 28.4 11.2 38.9 43.4 30.9 5.0 7.8 71.6 25.5 39.9 35.2 26.5 29.9 23.0 20.8 33.1 19.7 20.7 35.4 93.2 62.5 20.9 19.5 32.4 34.8 30.2 25.0 17.0 RIC8B "FLJ10620, hSyn, RIC8" ENSG00000111785 "RIC8 guanine nucleotide exchange factor B" Q9NVN3 12 106774621-106889316 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.4;Inhibitory neurons: 93.9;Microglial cells: 58.1;Oligodendrocyte precursor cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039970, HPA042746" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "HPA039970: , HPA042746: AB_2678143" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (9.87e-3)" "unprognostic (5.43e-2)" "unprognostic (3.28e-2)" "unprognostic (8.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.60e-1)" "unprognostic (1.99e-2)" "unprognostic (3.83e-1)" "unprognostic (1.10e-3)" "unprognostic (5.13e-2)" "unprognostic (3.65e-3)" "unprognostic (2.21e-1)" "unprognostic (3.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" 5.5 5.3 7.7 3.2 26.1 1.3 4.9 7.9 9.7 5.5 6.6 6.4 3.1 7.0 4.3 3.1 6.3 5.6 8.7 6.8 8.7 7.2 5.8 3.7 2.5 6.6 11.5 5.8 6.2 11.5 7.8 3.7 6.5 4.5 3.9 12.6 3.5 8.2 7.3 2.7 4.1 6.4 5.4 4.7 4.1 4.4 9.3 6.5 9.3 8.2 2.4 5.9 4.3 8.4 3.6 11.0 20.7 8.3 9.7 11.7 2.5 11.7 9.3 10.3 9.6 3.7 3.1 2.2 8.0 6.7 4.1 6.2 7.5 4.1 12.3 25.0 10.0 7.5 5.2 4.7 7.5 7.2 4.9 6.8 5.2 6.7 3.4 12.2 9.6 7.7 4.7 0.1 9.4 2.9 8.2 7.8 10.4 5.6 11.0 7.1 12.0 7.2 8.7 3.2 15.1 9.7 8.5 5.3 5.9 7.8 4.7 4.9 9.3 8.3 4.6 5.6 8.5 6.1 13.7 0.1 4.0 4.9 12.4 0.9 1.4 1.2 1.9 0.8 2.2 0.4 1.0 0.9 1.3 0.2 0.8 0.8 0.6 0.9 0.7 0.8 1.1 1.0 7.7 26.1 7.9 9.7 6.8 8.7 6.6 11.5 6.5 5.4 9.3 8.4 10.0 6.4 7.8 47.7 5.9 3.3 3.9 5.5 5.2 14.4 8.5 7.4 33.9 25.8 5.8 3.7 10.4 7.1 5.0 10.9 7.9 21.7 5.7 12.7 17.5 11.2 18.6 5.5 96.4 4.0 3.7 10.5 7.7 7.3 8.2 10.4 15.0 9.2 3.6 6.7 93.9 7.8 8.2 6.6 3.9 5.0 12.8 4.6 7.2 58.1 3.8 5.5 14.4 76.9 52.9 6.6 4.8 19.2 2.6 1.7 7.2 6.7 10.8 45.0 13.1 18.6 9.3 18.4 8.8 2.6 2.8 1.4 7.6 10.6 6.7 1.5 RIF1 "FLJ10599, FLJ12870" ENSG00000080345 "Replication timing regulatory factor 1" Q5UIP0 2 151409883-151508013 "Predicted intracellular proteins" "Cell cycle, DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036887, HPA036888" Supported Uncertain "Nucleoplasm,Nuclear bodies,Plasma membrane" No No "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Nuclear bodies, Plasma membrane" "HPA036887: AB_2675361, HPA036888: AB_2675362" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.71e-1)" "unprognostic (4.71e-3)" "unprognostic (5.87e-2)" "unprognostic (1.79e-2)" "unprognostic (3.73e-2)" "unprognostic (1.86e-1)" "unprognostic (2.51e-2)" "unprognostic (2.84e-2)" "unprognostic (1.80e-3)" "unprognostic (4.07e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-1)" "unprognostic (2.22e-1)" "unprognostic (1.57e-2)" "unprognostic (8.41e-2)" 6.1 5.0 4.4 7.4 8.4 21.7 10.0 13.8 7.0 6.5 2.6 5.6 4.3 8.2 4.0 5.6 5.6 5.6 3.5 4.6 5.1 5.5 6.7 5.1 8.5 4.4 5.1 11.2 7.0 6.8 3.5 8.0 5.4 6.0 6.1 8.2 7.7 5.0 7.5 7.2 4.6 6.2 4.9 6.5 6.1 11.0 4.5 10.7 9.1 9.5 7.9 7.3 4.6 13.8 20.8 17.4 26.8 20.5 10.7 13.8 25.9 24.8 18.0 21.6 25.5 28.9 16.4 39.2 21.7 17.3 17.9 21.3 41.2 17.1 36.1 27.8 19.8 63.4 21.4 21.0 11.2 64.7 20.2 10.3 11.3 38.8 28.7 12.3 21.3 23.5 52.2 32.6 22.1 13.8 38.3 22.9 43.2 11.2 22.9 38.4 42.1 26.1 11.6 24.9 24.2 18.8 32.0 14.6 16.5 18.8 12.9 23.1 27.0 32.9 22.8 20.3 26.7 16.0 29.6 55.4 15.3 25.5 22.5 6.3 2.5 3.0 4.3 1.7 4.9 4.0 3.6 3.2 1.8 3.1 4.8 3.7 2.8 7.7 3.5 1.6 2.8 1.7 4.4 8.4 13.8 7.0 4.6 5.1 4.4 5.1 5.4 4.9 4.5 13.8 53.1 96.1 49.7 41.1 43.5 49.3 47.5 21.9 33.0 48.2 30.4 29.8 38.2 28.6 38.0 14.7 31.3 39.2 40.3 19.6 1.9 38.5 22.6 38.0 61.7 48.0 25.0 84.3 68.5 21.9 35.9 51.3 34.7 65.0 34.1 88.6 27.1 19.7 23.0 47.1 72.4 30.9 14.2 26.4 27.0 14.0 43.8 37.6 30.2 48.7 44.1 35.8 32.0 73.9 126.3 29.9 23.5 34.3 45.1 53.2 14.9 12.9 21.3 42.8 85.5 106.5 51.2 122.8 113.1 28.9 41.6 40.9 45.3 58.9 34.6 45.4 RILPL1 FLJ39378 ENSG00000188026 "Rab interacting lysosomal protein like 1" Q5EBL4 12 123470054-123533719 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 62.4;skeletal muscle: 88.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 38.5;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041314 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 39: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA041314: AB_10795587" "unprognostic (2.21e-1)" "unprognostic (1.26e-1)" "unprognostic (3.71e-2)" "unprognostic (5.36e-2)" "unprognostic (3.12e-2)" "unprognostic (2.99e-3)" "unprognostic (1.94e-2)" "unprognostic (1.61e-1)" "unprognostic (2.65e-1)" "unprognostic (1.75e-1)" "unprognostic (2.30e-2)" "unprognostic (8.30e-2)" "unprognostic (4.25e-2)" "unprognostic (2.98e-1)" "unprognostic (2.32e-1)" "unprognostic (6.07e-3)" "unprognostic (2.81e-1)" 7.8 9.0 17.1 3.1 21.1 2.6 7.5 18.6 18.3 10.7 17.9 10.5 1.3 12.0 4.1 5.1 9.5 3.4 62.4 15.2 16.7 6.8 4.2 6.8 1.8 19.0 19.7 8.5 3.7 6.6 6.4 7.3 18.6 9.1 1.4 3.0 6.8 7.4 88.9 6.8 4.2 6.3 15.9 4.4 5.5 4.1 18.0 1.5 13.3 41.1 1.0 9.5 7.5 27.1 8.3 11.4 10.1 7.9 11.1 10.4 10.6 14.6 8.1 7.8 6.9 7.1 1.9 0.3 7.1 14.3 5.6 8.9 7.5 7.0 3.1 8.4 13.8 1.1 8.1 10.6 19.4 0.4 3.0 11.9 13.6 8.7 12.5 19.5 8.0 1.5 6.6 0.4 8.0 13.8 0.9 2.7 7.4 2.4 11.9 1.3 5.5 0.4 5.6 8.5 1.6 9.3 7.8 6.7 17.9 5.5 9.0 0.2 16.0 10.2 5.1 14.8 9.4 1.7 0.9 0.2 10.4 0.0 6.5 0.4 0.2 0.2 0.2 0.1 0.2 0.2 0.2 0.2 0.0 0.4 0.5 0.4 1.1 0.3 0.3 0.3 0.2 0.2 17.1 21.1 18.6 18.3 15.2 16.7 19.0 19.7 18.6 15.9 18.0 27.1 13.0 38.5 11.7 32.3 0.7 4.6 5.1 3.4 6.2 14.1 4.6 14.7 9.8 4.3 7.2 11.0 6.2 9.1 0.7 0.2 1.9 2.2 1.8 6.3 18.0 8.5 0.0 0.0 28.8 2.2 6.2 9.4 1.1 7.4 1.3 18.9 9.7 1.6 5.7 23.5 16.4 1.3 0.0 1.3 2.4 1.6 15.5 3.3 5.4 18.7 0.9 21.4 0.0 13.6 64.9 2.2 0.5 8.2 0.3 5.1 0.1 2.6 4.1 6.4 6.6 14.4 9.9 0.9 2.9 2.3 3.8 9.3 2.0 21.5 0.7 3.3 RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "brain: 35.7;choroid plexus: 24.5;testis: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 3.0;THP-1: 3.2" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.29e-2)" "unprognostic (9.81e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" "unprognostic (6.06e-3)" "unprognostic (9.58e-2)" "unprognostic (8.49e-3)" "unprognostic (7.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.69e-3)" "unprognostic (7.95e-2)" 0.1 0.2 7.9 0.4 10.8 0.1 0.0 35.7 22.0 0.1 24.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 11.0 11.7 0.0 0.0 0.2 0.8 14.9 10.1 0.1 0.1 0.3 0.1 0.2 26.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 19.6 0.7 0.2 28.4 13.5 1.0 0.4 0.0 0.5 0.0 0.0 32.4 0.4 1.3 0.5 0.4 0.7 0.3 0.0 0.5 1.4 0.6 0.7 0.0 0.0 0.3 0.6 0.2 0.4 0.3 0.3 0.0 0.1 1.4 0.4 0.6 0.3 0.5 0.0 2.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.2 0.3 0.5 0.6 3.0 1.7 0.6 0.6 0.1 1.2 1.6 0.2 0.1 0.1 0.8 0.1 1.2 0.0 0.2 0.1 0.1 3.2 0.1 1.0 0.7 0.5 0.3 0.0 0.4 0.3 0.5 0.7 1.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.3 7.9 10.8 35.7 22.0 11.0 11.7 14.9 10.1 26.2 19.6 13.5 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383374-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 49 "brain: 41.3;choroid plexus: 18.4;testis: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RH-30: 1.1;THP-1: 2.1" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (3.78e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.28e-1)" "unprognostic (5.35e-2)" "unprognostic (4.37e-1)" "unprognostic (3.61e-4)" "unprognostic (1.69e-2)" "unprognostic (7.11e-2)" 0.0 0.1 8.2 0.4 12.8 0.0 0.0 41.3 19.1 0.0 18.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 10.4 13.6 0.0 0.0 0.1 0.3 16.5 12.6 0.0 0.1 0.2 0.0 0.2 19.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 16.2 0.2 0.0 13.6 13.2 0.4 0.1 0.0 0.2 0.0 0.0 29.6 0.0 0.5 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.2 0.2 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.2 0.9 1.2 0.1 0.2 0.1 0.8 1.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 8.2 12.8 41.3 19.1 10.4 13.6 16.5 12.6 19.2 16.2 13.2 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3C ENSG00000183246 "RIMS binding protein 3C" A6NJZ7 22 21545678-21551461 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 6.1" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Late spermatids: 49.4;Spermatocytes: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (8.30e-2)" "unprognostic (4.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.15e-3)" "unprognostic (6.23e-2)" "unprognostic (2.17e-6)" "unprognostic (3.04e-1)" "unprognostic (3.29e-1)" "unprognostic (3.76e-6)" "unprognostic (1.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.6 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183247 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 15.0 14.6 12.5 13.5 13.7 21.5 14.7 16.6 21.3 12.9 14.1 13.3 13.0 11.6 12.2 13.5 12.3 7.8 16.3 12.5 14.7 14.2 18.1 10.3 14.3 13.5 13.5 14.8 16.7 11.3 15.1 12.1 13.5 12.0 12.7 19.4 11.8 9.3 21.4 11.3 11.2 9.3 13.9 14.6 13.3 12.6 13.7 13.7 11.9 14.2 13.6 13.2 12.1 15.9 19.0 22.0 20.3 38.5 25.9 28.6 32.1 48.1 29.0 33.0 43.2 30.4 32.5 41.7 53.1 21.3 51.6 21.7 34.2 27.4 44.9 29.3 18.5 20.3 44.0 42.9 23.6 38.5 27.2 18.5 20.8 40.1 39.8 25.0 27.0 30.8 31.7 25.4 38.0 31.9 46.4 47.8 22.5 10.6 23.9 51.9 38.3 61.9 25.7 16.9 23.7 17.9 27.5 28.3 35.6 29.6 29.6 36.4 28.5 41.2 28.9 33.0 51.8 25.3 36.4 95.2 24.0 39.7 38.4 17.9 26.2 15.8 24.6 30.7 34.4 24.0 31.5 27.8 29.4 18.6 33.9 36.5 5.0 30.7 23.8 29.2 31.7 22.7 12.5 13.7 16.6 21.3 12.5 14.7 13.5 13.5 13.5 13.9 13.7 15.9 14.9 9.6 12.8 7.8 16.9 26.4 17.9 25.2 12.5 16.2 11.1 11.4 20.5 10.0 17.4 7.3 12.5 19.6 26.9 6.4 17.6 17.3 1.3 10.7 18.0 14.0 9.6 8.4 10.9 14.9 24.8 21.1 14.8 10.5 27.9 12.7 8.2 8.1 18.3 13.5 11.0 12.7 18.3 9.4 9.2 3.0 13.4 11.0 5.4 3.7 16.5 13.4 14.4 9.0 15.0 11.4 10.1 16.1 19.1 10.4 11.8 17.3 13.3 17.7 6.6 17.4 22.9 23.5 20.7 10.1 18.9 17.4 19.6 19.4 12.6 12.0 RIOK3 SUDD ENSG00000101782 "RIO kinase 3" O14730 18 23453287-23486603 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 174.3" "Cell type enhanced" "Detected in all" "Distal enterocytes: 338.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001620, HPA024184" Approved Approved "Golgi apparatus,Plasma membrane,Centriolar satellite,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus, Centriolar satellite" "HPA001620: AB_1079815, HPA024184: AB_1856289" "unprognostic (7.99e-2)" "unprognostic (1.71e-2)" "unprognostic (2.39e-1)" "unprognostic (3.03e-2)" "unprognostic (1.05e-1)" "unprognostic (7.48e-2)" "unprognostic (8.98e-3)" "unprognostic (1.01e-1)" "unprognostic (5.10e-2)" "unprognostic (4.20e-1)" "prognostic unfavorable (4.10e-4)" "prognostic unfavorable (5.80e-4)" "unprognostic (3.90e-2)" "unprognostic (1.46e-1)" "unprognostic (5.44e-2)" "unprognostic (1.39e-1)" "unprognostic (2.71e-2)" 23.1 18.5 5.5 20.4 7.1 174.3 19.2 7.9 10.2 17.4 8.3 47.5 51.6 16.7 12.4 65.5 14.8 24.3 32.7 5.9 6.7 29.6 55.6 22.7 22.8 9.3 7.3 15.7 27.6 22.8 5.4 34.9 8.9 20.1 43.5 19.6 23.2 14.5 52.9 33.3 62.5 19.7 7.5 21.5 38.5 36.6 6.9 21.5 22.2 48.8 30.2 25.8 27.0 10.6 41.9 15.7 17.8 25.0 31.8 37.7 28.5 38.9 29.8 27.6 28.4 17.3 47.5 27.6 52.3 43.7 26.9 57.6 25.9 45.4 38.9 29.5 12.0 25.9 26.9 22.2 71.7 74.7 25.8 39.0 91.2 44.1 66.7 36.7 38.4 19.2 39.8 34.7 45.0 19.4 25.8 15.6 17.6 59.0 31.3 31.3 33.2 41.2 39.3 50.0 39.5 28.9 50.1 28.4 37.4 41.0 21.9 45.0 63.7 48.4 10.9 21.2 28.9 66.1 56.0 38.2 31.0 36.7 38.2 50.1 24.5 14.8 15.0 34.6 10.8 14.0 12.3 12.6 19.1 18.5 9.8 11.2 17.2 15.0 39.0 8.6 19.4 20.7 5.5 7.1 7.9 10.2 5.9 6.7 9.3 7.3 8.9 7.5 6.9 10.6 49.7 80.1 57.7 23.2 46.4 120.4 92.4 78.6 113.8 44.1 49.3 35.6 69.1 51.5 81.5 25.8 56.3 43.0 74.6 338.1 25.4 51.0 271.5 130.1 85.5 44.1 62.8 259.8 35.5 52.7 64.6 48.8 93.8 267.2 63.3 40.0 29.6 88.5 41.1 28.6 34.2 119.9 50.8 59.9 51.2 305.8 22.4 85.7 42.7 15.9 80.6 18.3 53.5 34.2 49.5 148.4 210.7 30.1 63.4 118.5 199.5 52.5 72.3 46.4 6.6 43.9 51.6 28.4 10.1 164.2 143.6 88.4 57.3 71.1 77.2 244.4 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063824-3115187 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favorable (6.71e-4)" 18.5 12.0 1.9 9.3 1.9 0.5 16.2 1.8 3.8 12.8 2.4 17.5 12.3 14.5 5.3 17.6 12.8 10.6 11.8 1.8 1.9 13.7 23.6 13.5 10.1 2.2 1.9 8.5 17.4 12.2 12.3 10.9 2.0 13.7 13.0 2.4 16.4 8.9 11.7 20.7 19.9 11.9 2.0 19.4 16.5 5.3 2.0 11.9 14.4 5.0 13.0 15.5 13.7 1.9 14.4 9.8 12.9 12.4 27.6 19.2 5.5 21.4 30.8 22.8 26.7 12.4 8.0 13.8 20.9 30.1 23.2 14.3 17.9 17.2 24.3 27.8 9.4 16.7 4.5 6.9 17.2 15.6 20.1 24.8 15.1 20.4 15.3 17.6 20.6 6.2 19.4 4.6 22.0 17.8 10.7 7.7 8.8 17.4 12.7 11.8 10.9 14.5 17.3 27.2 11.3 12.2 14.7 7.8 22.4 26.0 15.2 8.7 25.1 20.6 12.1 8.2 16.4 9.8 15.3 13.5 8.9 7.0 27.7 0.1 0.4 0.9 0.6 0.9 1.0 0.3 0.9 1.7 1.0 1.2 0.7 0.7 0.0 1.5 0.5 0.5 1.7 0.8 1.9 1.9 1.8 3.8 1.8 1.9 2.2 1.9 2.0 2.0 2.0 1.9 28.6 6.4 12.0 17.3 14.7 11.0 10.3 6.6 16.5 4.4 14.7 17.8 8.6 17.2 16.7 9.2 12.5 8.9 21.9 27.1 5.9 9.4 2.0 10.5 14.0 16.7 6.6 7.2 23.1 12.9 7.7 18.3 27.0 13.4 10.8 8.7 10.0 14.6 11.6 5.0 26.7 17.7 4.1 6.7 11.1 0.8 6.8 15.3 3.6 11.2 13.8 6.6 12.3 14.6 16.2 13.8 11.7 6.0 22.3 11.3 12.7 8.7 17.4 21.4 19.7 32.5 17.9 1.2 2.8 20.5 9.9 11.9 20.8 10.6 11.3 14.5 RND1 "ARHS, Rho6, RHOS" ENSG00000172602 "Rho family GTPase 1" Q92730 12 48857145-48865870 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 131.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 205.5;Ductal cells: 220.6;Exocrine glandular cells: 147.1;Pancreatic endocrine cells: 350.9" "Cancer enhanced" "Detected in many" "liver cancer: 16.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "SK-BR-3: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077800 Supported "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 30: Non-specific - Translation" "Cluster 15: Liver - Metabolism" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Vesicles, Plasma membrane, Actin filaments" "HPA077800: AB_2686854" "unprognostic (5.60e-2)" "unprognostic (3.21e-2)" "unprognostic (2.23e-1)" "unprognostic (1.16e-1)" "unprognostic (6.90e-2)" "unprognostic (1.32e-3)" "unprognostic (3.59e-2)" "unprognostic (7.43e-2)" "unprognostic (2.21e-3)" "unprognostic (2.97e-1)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (3.89e-1)" "unprognostic (8.38e-3)" "unprognostic (6.18e-2)" "unprognostic (6.60e-2)" "unprognostic (3.35e-3)" 9.6 0.8 24.4 2.6 26.9 1.8 5.6 18.9 40.6 1.6 15.4 4.8 2.4 3.9 1.0 3.1 2.7 14.5 7.3 26.8 20.4 4.4 131.8 37.9 1.0 21.4 23.6 1.2 2.8 2.4 8.0 1.2 21.9 6.5 1.9 1.7 3.9 0.8 1.0 1.6 2.6 2.4 19.9 0.8 23.4 0.9 22.1 2.4 15.4 0.6 2.3 14.0 2.7 23.2 1.1 7.9 3.8 2.0 0.8 0.0 0.6 0.0 0.4 1.2 1.3 4.9 1.7 6.0 1.4 0.0 0.4 0.1 3.1 0.3 0.7 1.8 1.9 0.8 0.0 3.0 0.4 1.8 1.1 0.0 0.2 0.6 0.8 0.0 2.0 3.9 0.2 6.0 0.0 10.2 0.9 0.5 8.9 13.6 0.5 1.9 0.4 2.6 1.1 1.5 0.0 1.0 0.2 67.7 0.3 9.1 6.9 0.4 0.2 0.0 0.7 0.0 0.9 2.9 5.4 10.9 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 24.4 26.9 18.9 40.6 26.8 20.4 21.4 23.6 21.9 19.9 22.1 23.2 28.9 28.9 205.5 5.9 8.5 11.5 8.4 14.1 9.1 2.5 37.5 25.4 3.8 18.6 27.5 1.8 8.4 1.1 9.0 21.7 0.0 220.6 0.4 4.5 2.0 87.3 31.5 2.7 10.6 147.1 0.7 10.5 55.5 12.6 15.2 0.8 6.1 10.9 1.2 0.0 2.7 11.4 18.3 0.8 24.1 0.0 0.0 6.6 14.2 1.0 6.4 3.0 0.0 7.1 1.0 350.9 42.2 0.4 6.5 19.5 11.1 1.7 7.7 3.6 0.0 5.8 16.7 0.8 1.6 4.3 10.5 1.5 9.9 0.6 5.4 8.6 RNF114 "PSORS12, ZNF313" ENSG00000124226 "Ring finger protein 114" Q9Y508 20 49936336-49953885 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 1500.7;Late spermatids: 923.4;Spermatocytes: 558.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 561.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021184 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA021184: AB_1859185" "unprognostic (8.38e-2)" "unprognostic (3.56e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (8.10e-6)" "unprognostic (1.56e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (2.50e-2)" "unprognostic (1.03e-2)" "unprognostic (2.12e-1)" "unprognostic (3.99e-1)" "unprognostic (2.70e-2)" "unprognostic (2.54e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.36e-2)" 32.8 32.0 43.3 29.7 48.2 51.6 31.2 46.6 45.1 37.2 41.0 45.0 42.8 28.7 32.8 30.8 34.7 28.8 37.6 40.4 44.9 48.6 49.0 37.9 39.3 47.3 46.5 39.0 52.2 30.2 28.1 35.1 46.6 33.9 40.0 16.7 41.0 34.1 83.3 24.2 40.8 25.4 47.1 52.4 35.9 166.1 47.2 39.1 37.9 52.8 37.3 28.9 28.7 49.9 83.9 80.5 42.9 43.7 84.3 57.8 118.0 73.0 86.2 153.2 64.4 241.7 67.6 39.9 142.9 40.1 91.6 66.3 62.5 74.7 90.6 73.5 44.3 51.5 50.1 173.2 73.3 95.3 59.5 51.5 68.8 58.4 39.9 52.6 36.8 69.7 98.0 46.7 45.5 281.0 82.6 98.0 42.3 67.4 114.3 85.7 45.5 73.6 83.4 67.9 63.2 45.4 88.8 561.6 118.5 45.4 149.7 86.6 47.8 134.6 62.3 71.6 87.0 93.6 107.1 79.2 76.4 63.2 76.1 112.2 97.8 86.1 48.1 92.5 53.1 63.9 52.6 48.6 75.3 71.2 61.6 50.2 100.5 57.8 112.5 61.9 68.9 92.7 43.3 48.2 46.6 45.1 40.4 44.9 47.3 46.5 46.6 47.1 47.2 49.9 47.1 48.1 53.7 13.4 69.9 107.2 127.8 103.4 63.2 24.4 50.7 55.8 46.1 41.5 101.4 69.9 12.5 91.3 61.0 61.7 72.4 107.5 1500.7 72.2 36.3 55.3 60.4 45.4 22.8 101.1 77.4 61.9 41.3 71.4 45.0 31.9 46.1 63.7 110.6 40.4 24.4 79.5 42.7 76.6 146.5 923.4 70.5 66.0 71.2 27.2 96.3 38.0 56.7 10.6 26.2 92.1 77.9 59.8 81.9 122.5 96.4 120.9 75.8 22.6 39.5 45.5 59.2 558.0 138.4 45.8 87.1 124.8 69.2 46.5 80.4 113.3 RNF145 FLJ31951 ENSG00000145860 "Ring finger protein 145" Q96MT1 5 159157409-159210053 "Enzymes, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 4 "B-cells: 11.4;granulocytes: 16.0;T-cells: 6.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036562 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA036562: AB_10696657" "unprognostic (1.57e-1)" "unprognostic (9.02e-3)" "unprognostic (4.11e-2)" "unprognostic (3.88e-2)" "unprognostic (3.24e-2)" "unprognostic (2.93e-2)" "prognostic unfavorable (1.64e-6)" "unprognostic (1.35e-1)" "unprognostic (1.02e-2)" "unprognostic (1.54e-1)" "unprognostic (3.53e-1)" "unprognostic (1.67e-1)" "unprognostic (8.92e-3)" "unprognostic (1.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.10e-1)" "unprognostic (1.39e-1)" 27.4 39.3 13.7 39.4 15.9 20.4 28.2 16.2 16.1 24.7 18.6 26.4 12.2 21.0 30.9 53.1 16.9 48.3 18.8 15.6 19.8 19.5 15.3 73.6 38.7 11.1 13.1 29.0 12.3 47.7 19.4 52.4 11.6 25.9 29.3 33.8 25.6 32.7 9.0 22.3 16.6 27.4 14.3 29.2 26.7 12.1 20.3 26.5 33.8 13.7 48.4 68.1 24.4 14.7 65.5 63.5 95.2 115.1 98.5 43.6 18.6 51.3 88.9 46.3 74.6 22.2 52.9 22.4 89.7 45.3 87.9 83.1 75.9 67.3 80.9 92.7 27.2 47.2 68.5 18.4 42.1 31.4 43.2 27.0 118.8 43.2 63.0 64.7 46.2 53.6 47.7 83.6 44.1 1.9 36.1 9.8 41.3 20.5 32.0 47.3 41.6 44.8 61.4 22.3 34.5 63.9 51.8 54.7 86.5 64.7 38.5 28.4 49.7 51.6 47.0 41.9 92.1 18.4 27.6 20.6 60.3 38.4 113.1 3.5 2.5 16.0 3.0 2.6 3.5 11.4 4.4 3.6 1.9 5.1 5.8 4.0 9.5 2.3 2.3 2.7 6.3 1.3 13.7 15.9 16.2 16.1 15.6 19.8 11.1 13.1 11.6 14.3 20.3 14.7 34.1 112.2 244.1 25.1 62.9 122.7 102.0 90.0 73.4 106.7 97.2 77.3 12.7 65.8 114.0 36.8 58.4 2.8 55.1 98.4 19.6 75.0 28.9 27.5 37.1 75.7 54.1 67.5 89.2 114.4 24.3 45.7 52.0 36.7 69.1 30.2 127.8 19.5 45.5 114.4 74.2 41.8 32.6 115.0 240.8 39.5 46.3 69.4 65.8 52.5 153.9 56.1 47.4 40.2 38.9 108.6 53.7 51.9 38.1 123.8 16.9 10.6 65.6 53.4 46.0 25.4 46.5 19.2 34.8 81.9 99.4 10.9 69.3 19.0 72.0 163.1 RNF146 "dactylidin, dJ351K20.1, DKFZp434O1427" ENSG00000118518 "Ring finger protein 146" Q9NTX7 6 127266682-127288567 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway, Wnt signaling pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027158, HPA027209" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" Nucleoplasm "HPA027158: AB_10600772, HPA027209: AB_10602312" "unprognostic (8.22e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-1)" "unprognostic (1.32e-1)" "unprognostic (1.38e-2)" "unprognostic (1.17e-2)" "unprognostic (1.37e-1)" "unprognostic (5.47e-3)" "unprognostic (1.87e-1)" "unprognostic (6.74e-2)" "prognostic favorable (5.26e-5)" "unprognostic (2.65e-2)" "prognostic favorable (7.32e-4)" "unprognostic (4.04e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "unprognostic (2.15e-2)" 52.9 37.0 49.5 32.4 56.0 10.6 42.7 79.4 61.2 48.1 36.2 40.5 21.9 57.4 60.8 25.3 42.4 38.6 46.9 50.7 51.6 37.1 31.8 38.7 35.1 53.2 52.1 49.5 23.3 40.0 33.3 51.8 56.8 31.7 30.9 48.1 31.2 34.5 114.9 29.5 31.1 45.9 55.2 47.1 29.9 31.3 52.5 24.3 47.1 91.5 33.3 36.9 34.3 61.5 13.2 16.2 60.3 53.6 54.7 54.3 22.2 43.5 69.0 22.8 32.4 21.3 19.3 23.6 30.3 35.7 36.2 16.4 18.1 20.4 32.9 27.6 16.0 30.3 21.8 30.0 54.0 18.0 20.6 47.6 42.1 26.1 51.1 52.5 40.6 23.2 33.0 22.5 50.7 25.2 17.9 32.0 22.1 8.1 17.1 22.6 15.7 12.1 32.4 14.3 36.0 36.6 17.1 23.6 27.7 35.5 16.1 60.8 48.3 39.7 13.1 41.8 31.7 32.3 22.0 15.6 30.5 31.0 38.5 27.5 30.0 26.6 14.3 32.4 14.7 17.4 12.2 16.3 22.8 17.9 11.0 15.5 37.0 19.8 40.1 11.7 15.0 16.1 49.5 56.0 79.4 61.2 50.7 51.6 53.2 52.1 56.8 55.2 52.5 61.5 24.6 35.3 29.3 35.6 23.7 17.7 14.3 15.1 18.8 34.7 16.9 14.7 38.9 31.5 16.7 9.2 4.2 29.0 14.7 13.5 41.1 28.0 52.5 15.7 29.5 30.5 20.4 12.8 53.5 15.8 27.2 50.6 7.1 11.5 22.2 28.1 31.4 30.5 26.3 30.3 54.5 12.1 38.7 68.4 24.6 45.4 69.6 29.9 46.2 42.2 31.1 41.1 28.8 56.3 76.5 18.0 17.0 66.5 9.3 26.3 15.7 51.7 23.9 20.9 32.9 36.2 31.9 41.7 24.9 15.0 20.0 38.4 20.8 36.0 10.9 25.9 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 619.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 619.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" 26.7 15.2 7.7 40.3 7.5 52.3 16.3 7.7 9.7 17.7 12.3 15.7 16.8 12.4 16.3 35.5 16.9 18.9 12.5 7.6 8.9 16.3 26.6 30.5 18.3 9.9 8.5 15.9 22.3 17.9 10.4 21.8 9.6 12.6 15.8 7.8 18.3 10.1 8.5 25.6 18.2 12.9 8.5 53.1 19.1 15.8 9.1 15.2 12.2 9.4 19.6 29.1 22.7 10.9 19.9 11.4 8.8 11.3 31.6 31.3 49.7 24.0 31.8 32.1 35.8 29.0 51.6 6.1 28.3 23.9 42.9 39.0 12.5 24.6 29.7 16.9 16.6 12.4 9.9 50.0 42.1 13.4 19.2 28.9 40.0 37.9 25.1 24.7 58.9 13.0 10.7 18.0 32.4 16.9 18.8 14.0 6.1 27.1 20.0 11.5 14.2 23.4 38.0 48.0 11.5 8.5 14.4 36.0 37.2 9.5 9.7 17.8 39.6 16.2 9.1 24.5 5.3 35.5 22.5 0.2 5.2 18.6 12.2 44.0 73.6 90.3 43.8 118.1 41.8 13.2 40.0 45.3 27.9 8.5 28.2 30.2 619.9 15.3 134.1 52.5 53.8 69.8 7.7 7.5 7.7 9.7 7.6 8.9 9.9 8.5 9.6 8.5 9.1 10.9 19.9 48.1 48.1 44.7 55.2 76.9 78.1 63.5 54.7 20.4 29.7 15.9 13.0 41.5 48.4 55.2 56.3 65.2 112.4 53.1 1.9 59.1 97.9 41.8 31.9 30.0 8.5 22.7 82.8 42.2 73.0 53.5 37.2 63.1 39.2 17.3 27.1 46.2 85.9 8.4 71.6 31.7 12.2 278.6 144.2 37.2 30.7 209.0 40.9 50.6 116.5 11.6 61.8 34.7 59.6 54.3 52.3 19.5 125.5 73.5 45.9 25.8 44.8 20.7 59.2 40.5 30.1 36.6 40.3 128.3 91.6 128.1 115.7 23.8 32.8 154.1 RNF165 "Ark2C, ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;retina: 18.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.0;Cone photoreceptor cells: 100.1;Excitatory neurons: 47.4;Horizontal cells: 80.8;Inhibitory neurons: 34.4;NK-cells: 41.2;Oligodendrocyte precursor cells: 35.7;Rod photoreceptor cells: 49.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 10.1;HaCaT: 7.3;HeLa: 7.5;RPMI-8226: 6.4;SCLC-21H: 13.9;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA041615: AB_2677582, HPA047798: AB_2680158" "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 0.6 0.5 3.1 0.3 3.7 0.3 0.7 7.6 6.4 0.6 0.0 0.4 0.0 0.2 1.9 1.2 1.2 0.3 1.0 4.7 0.2 1.6 5.2 0.3 0.2 0.0 0.3 0.0 0.3 2.4 4.1 0.2 0.0 2.2 0.1 18.2 0.8 1.3 1.5 1.2 0.3 0.1 0.1 2.0 0.2 0.5 1.3 0.9 4.0 0.8 0.4 0.3 0.5 1.9 1.6 0.1 10.1 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 7.3 0.5 1.0 0.0 0.0 1.1 0.1 7.5 0.0 0.0 3.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 2.3 0.0 0.2 0.0 0.0 2.6 0.9 1.7 0.4 1.3 2.7 0.6 6.4 0.7 2.2 13.9 13.2 2.0 0.0 0.0 0.9 0.3 0.5 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 3.1 3.7 7.6 6.4 4.7 0.2 0.0 0.3 0.0 0.1 1.3 1.9 9.1 3.2 1.7 1.6 0.3 2.7 9.5 12.9 28.5 44.0 2.9 7.2 8.4 1.5 2.8 0.0 100.1 0.2 10.0 0.2 3.9 0.0 3.8 1.5 9.3 5.0 0.0 0.0 47.4 0.0 0.3 2.4 0.0 0.6 0.0 0.0 1.8 8.9 0.1 80.8 34.4 0.0 2.0 1.9 1.3 5.1 2.5 0.4 1.8 1.9 0.3 5.0 41.2 35.7 1.8 0.1 0.0 4.1 0.4 5.0 0.1 0.1 0.6 49.1 0.0 4.5 0.7 0.4 0.9 3.7 2.0 0.3 3.2 3.2 0.0 2.4 RNF166 "MGC14381, MGC2647" ENSG00000158717 "Ring finger protein 166" Q96A37 16 88696499-88706408 "Enzymes, Predicted intracellular proteins" "Autophagy, Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.2;lymphoid tissue: 101.6" "Cell type enhanced" "Detected in all" "dendritic cells: 132.3;NK-cells: 111.2;T-cells: 73.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "NB-4: 108.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042970 Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane, Cytosol" "HPA042970: AB_10796682" "unprognostic (3.01e-2)" "unprognostic (6.98e-3)" "unprognostic (3.96e-2)" "unprognostic (5.36e-3)" "unprognostic (1.23e-1)" "unprognostic (2.71e-2)" "unprognostic (6.52e-2)" "unprognostic (5.86e-2)" "unprognostic (4.88e-2)" "unprognostic (2.38e-2)" "prognostic favorable (1.04e-4)" "unprognostic (3.22e-2)" "prognostic unfavorable (9.45e-6)" "unprognostic (1.54e-1)" "unprognostic (3.91e-2)" "unprognostic (1.28e-1)" "unprognostic (2.69e-2)" 22.7 18.4 16.1 28.8 16.2 91.2 16.0 14.4 24.5 18.3 13.9 18.3 14.1 16.6 3.2 11.8 20.0 14.0 21.3 15.5 15.0 20.7 23.4 48.3 40.4 19.4 16.8 17.8 19.5 5.4 17.6 8.2 17.6 19.7 4.9 3.4 14.8 5.8 21.3 11.8 37.2 6.3 16.9 101.6 17.8 12.8 20.9 18.0 18.8 8.2 21.1 18.1 14.4 20.0 10.3 15.9 12.5 18.4 5.8 5.0 23.3 10.3 6.5 11.8 5.3 11.1 6.4 12.4 13.0 6.0 6.8 11.1 7.2 6.8 4.7 6.4 21.7 16.7 12.4 18.7 15.9 16.7 20.4 6.0 6.4 9.4 8.2 6.9 12.4 20.6 28.6 8.8 5.0 20.3 38.9 108.0 20.3 4.4 21.5 36.3 7.8 32.2 5.3 4.5 11.8 12.3 23.9 4.8 12.1 5.9 13.4 53.3 18.6 8.7 13.4 13.5 12.5 19.9 13.5 31.6 7.8 62.8 12.4 7.0 25.6 61.3 31.6 19.1 27.7 4.2 19.3 27.6 23.8 3.9 15.7 22.9 40.4 11.3 22.7 14.8 21.8 21.6 16.1 16.2 14.4 24.5 15.5 15.0 19.4 16.8 17.6 16.9 20.9 20.0 15.2 9.6 3.6 7.8 23.5 4.8 4.6 2.4 6.2 10.1 6.0 7.1 2.8 4.3 3.1 7.3 6.2 8.8 132.3 2.3 9.8 6.5 1.4 5.2 7.4 11.0 4.9 13.7 6.5 9.2 9.6 8.8 8.2 4.9 21.0 12.3 8.6 4.8 38.8 8.4 4.8 3.1 2.0 46.7 32.4 2.5 9.3 52.4 10.6 15.0 41.5 11.7 111.2 3.5 4.5 5.5 1.0 7.9 55.1 4.5 1.8 7.0 4.7 9.6 6.6 8.9 10.0 9.1 9.9 4.8 5.8 3.7 73.1 12.2 3.7 1.9 RNF39 "FAP216, HZFw1, LIRF" ENSG00000204618 "Ring finger protein 39" Q9H2S5 6 30070266-30075887 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 24.5;skin 1: 63.3;vagina: 21.6" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 79.9;Basal respiratory cells: 96.2;Club cells: 55.7;Prostatic glandular cells: 57.2;Urothelial cells: 233.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 4.5;U-266/84: 3.6" "Region enhanced" "Detected in many" "cerebral cortex: 8.1" "Group enriched" "Detected in many" 4 "cerebellum: 9.0;cerebral cortex: 8.0;hippocampal formation: 4.4" "CAB019278, HPA047115" Uncertain Approved "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane, Centrosome" "CAB019278: , HPA047115: AB_2679938" "unprognostic (1.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.53e-2)" "unprognostic (5.72e-3)" "unprognostic (3.08e-2)" "unprognostic (4.05e-2)" "unprognostic (1.38e-1)" "unprognostic (2.22e-2)" "unprognostic (1.59e-2)" "unprognostic (4.45e-3)" "unprognostic (3.61e-2)" "unprognostic (2.06e-4)" "unprognostic (5.61e-2)" "unprognostic (1.31e-1)" "unprognostic (2.04e-1)" "unprognostic (2.57e-2)" 1.1 0.8 0.0 0.0 0.1 0.0 8.6 0.1 0.3 16.8 0.0 0.6 0.2 0.6 0.0 24.5 1.4 0.1 0.3 0.1 0.1 0.4 0.2 1.9 0.0 0.2 0.0 1.3 1.7 0.1 1.4 0.0 0.2 7.2 0.0 0.5 15.8 0.1 0.4 63.3 0.5 0.0 0.0 0.2 8.3 1.6 0.1 0.0 0.4 0.0 0.4 3.9 21.6 0.1 1.2 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.6 0.0 0.2 1.1 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.7 0.0 0.9 0.3 0.2 0.0 0.4 0.0 0.5 0.0 4.5 0.0 0.1 0.1 0.0 0.8 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.1 0.8 3.6 0.3 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.0 0.2 0.0 0.1 0.1 0.3 3.2 2.7 0.0 0.0 17.8 79.9 96.2 42.1 0.5 23.7 28.6 0.3 7.2 55.7 0.0 0.0 0.0 0.8 1.8 0.0 6.4 0.6 3.6 2.4 1.1 0.0 0.0 0.0 3.3 0.0 1.2 17.3 20.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 14.2 0.0 2.1 0.0 1.2 0.4 3.6 0.0 0.6 0.0 0.0 0.0 0.0 24.2 2.2 1.2 0.0 57.2 0.1 0.0 13.0 0.4 0.0 0.0 3.0 0.1 0.4 11.3 23.9 0.7 0.6 0.0 0.9 233.1 ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 309.4;Inhibitory neurons: 1518.9;Oligodendrocyte precursor cells: 348.3;Oligodendrocytes: 479.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" 12.4 8.6 12.7 10.7 13.7 0.2 4.9 4.3 9.5 13.4 0.0 7.8 3.1 9.5 7.2 12.3 4.7 7.7 6.7 7.8 10.8 3.1 3.6 7.6 9.3 8.8 16.3 16.4 1.9 1.8 7.4 7.8 9.9 12.9 6.0 3.9 5.4 11.9 4.5 20.5 4.3 10.5 7.5 9.0 4.8 10.3 15.5 13.3 4.8 5.4 18.2 13.9 11.1 12.4 0.2 26.9 25.7 41.3 35.0 22.8 1.4 21.1 28.0 16.3 13.8 0.6 11.5 0.0 0.1 26.2 13.0 10.9 31.5 21.6 20.5 0.4 39.1 16.4 51.4 43.4 8.4 0.3 4.1 38.3 28.9 61.9 29.1 30.5 16.5 0.0 2.2 49.0 16.8 13.1 0.0 0.1 32.8 7.9 9.6 0.9 27.2 0.3 0.1 8.9 19.7 13.7 45.5 9.9 16.2 24.6 31.8 0.4 0.3 54.1 23.4 32.7 36.1 1.7 0.0 0.0 49.2 0.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 12.7 13.7 4.3 9.5 7.8 10.8 8.8 16.3 9.9 7.5 15.5 12.4 4.3 3.2 11.0 81.0 1.9 33.1 20.6 17.9 39.9 11.7 4.1 3.6 3.6 0.0 9.0 7.3 4.2 9.7 0.0 0.1 0.0 0.5 23.9 1.6 23.2 14.3 1.2 4.0 309.4 0.2 8.3 34.6 3.6 2.3 1.3 5.1 16.1 0.3 1.5 1.7 1518.9 1.4 22.4 2.6 10.0 65.9 19.9 1.5 14.2 51.5 1.9 5.7 0.0 348.3 479.3 0.2 5.1 24.5 1.3 20.5 4.9 0.4 2.9 1.0 13.1 24.7 16.8 2.7 7.0 30.3 33.8 5.6 0.9 71.1 2.6 52.7 ROBO2 KIAA1568 ENSG00000185008 "Roundabout guidance receptor 2" Q9HCK4 3 75906695-77649964 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;retina: 15.4" "Group enriched" "Detected in many" 24 "Excitatory neurons: 3438.7;Inhibitory neurons: 4706.0" "Cancer enhanced" "Detected in many" "glioma: 3.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "BJ hTERT+: 29.8;HEL: 83.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013371, HPA013975" Approved Approved "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA 1900000 "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Centriolar satellite" "HPA013371: AB_1856391, HPA013975: " "unprognostic (1.14e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-2)" "unprognostic (7.25e-3)" "unprognostic (1.82e-2)" "unprognostic (5.93e-3)" "unprognostic (3.87e-1)" "unprognostic (2.83e-3)" "unprognostic (4.07e-2)" "unprognostic (4.23e-1)" "unprognostic (2.90e-2)" "unprognostic (1.76e-1)" "unprognostic (3.08e-4)" "unprognostic (2.06e-1)" "unprognostic (1.07e-1)" "unprognostic (1.99e-2)" "unprognostic (9.65e-3)" 0.7 2.4 10.1 0.5 13.6 0.0 0.6 0.0 14.2 2.4 0.0 0.8 0.5 2.1 0.4 4.8 0.1 2.3 0.6 10.4 1.7 1.8 1.2 10.0 1.5 14.8 13.1 7.0 1.6 2.8 1.5 5.2 14.3 1.2 0.4 15.4 1.6 5.7 0.1 2.3 0.7 1.4 16.7 2.9 0.7 3.7 4.9 9.3 0.1 0.4 2.2 1.2 1.7 8.1 0.0 0.0 2.2 0.0 7.5 8.1 0.1 0.3 29.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.0 9.8 83.9 1.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.0 0.5 0.0 5.1 9.1 0.0 0.0 1.1 5.1 12.2 0.0 0.0 0.0 0.3 0.4 0.0 0.1 0.0 0.5 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.1 13.6 0.0 14.2 10.4 1.7 14.8 13.1 14.3 16.7 4.9 8.1 0.7 0.0 0.5 164.6 0.0 1.8 2.0 0.4 19.4 30.8 0.2 1.0 2.4 1.5 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.2 1.0 1.7 1.1 0.0 0.0 3438.7 0.0 0.1 10.6 0.0 3.2 0.0 2.3 3.3 0.7 0.1 52.2 4706.0 3.0 0.0 0.0 2.8 3.4 3.1 0.1 0.0 54.4 0.0 2.0 0.0 63.3 52.4 0.2 0.0 6.0 0.0 0.8 0.3 0.1 0.1 5.6 0.0 0.1 0.9 2.9 1.1 15.7 1.1 0.1 0.2 40.5 0.5 0.2 ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.4" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Muller glia cells: 45.3" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "AF22: 18.4" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" 2.8 1.8 0.5 0.0 0.3 0.2 1.9 0.0 3.2 0.7 0.0 1.3 0.3 0.8 0.0 0.7 2.0 0.0 1.8 0.7 0.2 1.6 0.4 1.1 0.1 0.9 0.9 6.4 0.7 0.0 0.8 0.2 0.2 1.4 0.0 0.2 1.2 0.0 0.5 0.7 0.9 0.8 0.2 1.6 0.6 1.2 1.7 0.0 1.4 0.0 0.0 0.7 1.2 0.9 0.0 0.0 18.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.6 0.9 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.0 3.2 0.7 0.2 0.9 0.9 0.2 0.2 1.7 0.9 13.2 0.0 7.3 32.3 0.4 2.9 14.5 16.2 4.0 1.9 5.9 10.9 2.7 1.5 5.9 12.9 0.0 0.2 8.5 2.1 0.0 9.3 0.4 0.4 0.5 11.4 3.5 2.1 6.9 0.8 0.2 19.0 0.5 0.7 8.9 19.0 7.5 0.3 1.6 0.0 2.3 2.4 10.2 1.6 20.1 0.6 13.4 8.0 3.6 11.2 1.6 45.3 8.2 4.5 9.2 1.2 2.5 8.2 0.7 8.2 1.0 0.8 0.6 2.1 0.0 14.3 4.4 10.1 10.8 2.3 1.0 0.1 3.6 3.5 2.7 6.5 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "retina: 1186.9" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 3239.7" "Cancer enriched" "Detected in all" 6 "glioma: 14.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Cell line enhanced" "Detected in many" "HSkMC: 25.2;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028910, HPA073279" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA028910: AB_2672824, HPA073279: " "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (4.05e-1)" "prognostic favorable (2.20e-4)" "unprognostic (2.20e-1)" "unprognostic (9.87e-2)" "unprognostic (7.65e-3)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.61e-1)" "unprognostic (4.65e-1)" "unprognostic (1.02e-1)" "unprognostic (7.24e-2)" 12.8 7.9 57.9 2.2 60.5 1.2 9.3 56.8 67.4 9.1 48.1 9.8 1.8 7.7 4.7 7.6 10.7 4.6 8.1 54.5 59.0 7.0 7.1 6.0 2.5 67.4 61.0 13.5 3.6 5.2 7.0 1.4 62.1 8.2 2.6 1186.9 4.2 5.0 3.3 5.4 5.3 5.4 60.0 7.5 7.0 6.2 63.1 1.6 6.0 3.7 2.5 9.6 7.3 62.1 3.2 1.9 3.1 6.6 4.5 22.0 0.6 2.1 3.7 4.3 2.8 0.9 5.3 3.0 15.9 12.2 2.0 4.1 1.5 4.2 1.1 5.3 3.0 3.1 8.6 4.0 13.0 1.1 0.9 25.2 5.9 4.5 9.1 15.1 7.0 1.2 4.0 6.5 9.1 8.3 1.7 2.3 0.8 1.7 5.9 1.6 2.6 19.1 5.0 1.8 3.3 5.1 5.0 5.8 2.5 0.5 8.1 1.4 8.3 7.2 2.7 8.3 2.5 2.9 31.9 2.4 14.2 3.1 1.5 0.0 0.4 0.3 0.3 0.1 0.9 0.2 1.2 0.3 0.2 0.3 0.5 0.6 0.1 2.7 0.4 0.3 0.4 0.5 57.9 60.5 56.8 67.4 54.5 59.0 67.4 61.0 62.1 60.0 63.1 62.1 19.9 0.0 4.4 4.9 0.6 3.7 5.7 5.0 7.4 356.6 3.8 7.2 2.5 2.8 2.3 5.5 594.2 1.0 0.6 2.4 1.9 1.6 2.0 1.0 4.1 31.3 4.2 0.0 0.2 3.1 0.2 4.1 1.1 1.0 1.3 1.2 21.8 1.7 1.1 171.6 0.5 2.8 0.0 1.9 0.8 7.9 19.0 1.2 3.6 1.9 1.3 516.9 1.0 1.0 6.5 2.1 2.5 5.7 0.6 3.1 3.1 4.7 2.7 3239.7 0.0 2.5 4.3 1.6 5.1 5.3 1.0 0.7 1.5 4.0 2.9 3.1 RP2 "NM23-H10, NME10, TBCCD2" ENSG00000102218 "RP2 activator of ARL3 GTPase" O75695 X 46837043-46882358 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "GTPase activation" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 49.5" "Cell type enhanced" "Detected in many" "Kupffer cells: 62.8;Langerhans cells: 72.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000234, HPA000909" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA000234: AB_1079831, HPA000909: AB_2666140" "unprognostic (2.26e-1)" "unprognostic (6.01e-3)" "unprognostic (2.79e-2)" "unprognostic (2.98e-1)" "unprognostic (1.69e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.97e-4)" "unprognostic (2.58e-2)" "unprognostic (9.76e-3)" "unprognostic (3.10e-2)" "unprognostic (3.79e-3)" "unprognostic (9.75e-2)" "unprognostic (6.15e-3)" "unprognostic (2.96e-2)" "unprognostic (9.66e-2)" "unprognostic (1.61e-1)" "unprognostic (4.28e-3)" 10.9 8.9 1.9 15.6 2.3 49.5 7.2 2.6 2.3 7.9 3.6 10.1 10.6 6.9 4.0 12.9 6.8 12.7 4.8 1.7 2.7 6.7 13.2 11.8 12.9 3.3 2.8 6.5 4.6 7.4 1.7 25.2 3.5 6.7 10.5 4.2 4.4 5.3 2.0 5.3 11.0 9.0 3.5 13.2 8.1 4.0 2.3 9.8 6.1 3.6 11.2 10.4 4.2 4.6 21.8 10.3 20.4 11.0 15.7 19.4 48.0 27.4 21.5 23.8 23.9 44.6 18.2 25.8 10.7 29.3 20.1 14.0 19.8 20.0 32.1 11.5 11.5 13.9 11.7 10.7 17.9 29.2 46.4 15.1 13.0 18.8 10.1 13.3 30.5 11.4 6.2 13.1 27.0 1.9 18.1 26.8 12.5 14.8 19.5 22.9 27.9 13.8 15.3 22.0 7.4 10.0 24.4 14.9 12.4 36.2 16.8 27.1 27.1 18.3 13.6 29.1 9.8 4.9 6.8 15.4 9.5 20.4 19.5 62.6 22.6 35.5 6.1 30.8 5.0 10.3 4.9 5.3 22.6 9.6 6.0 5.7 43.5 7.6 36.3 7.6 6.1 12.2 1.9 2.3 2.6 2.3 1.7 2.7 3.3 2.8 3.5 3.5 2.3 4.6 9.6 9.6 7.4 3.9 18.9 15.8 3.2 6.1 15.4 3.1 7.8 6.1 1.7 7.2 5.1 9.2 2.1 23.2 12.0 28.6 0.0 4.7 2.8 15.8 14.5 8.6 3.6 10.3 3.1 5.3 6.4 10.3 12.8 14.9 12.0 4.0 12.5 20.1 24.3 0.0 4.0 9.4 2.0 62.8 72.9 1.7 5.6 44.7 21.4 6.5 36.6 3.6 6.2 12.1 5.9 11.6 13.4 5.7 13.2 8.2 9.8 3.6 14.5 5.5 6.6 7.7 10.5 7.8 4.6 36.4 14.9 38.2 11.4 4.7 10.5 13.6 RPE ENSG00000197713 Ribulose-5-phosphate-3-epimerase Q96AT9 2 210002565-210022260 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 130000 "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (5.07e-2)" "unprognostic (8.15e-2)" "unprognostic (3.06e-1)" "unprognostic (2.34e-3)" "unprognostic (2.00e-1)" "unprognostic (2.53e-2)" "prognostic unfavorable (1.42e-6)" "unprognostic (1.59e-3)" "unprognostic (1.69e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.00e-6)" "unprognostic (2.33e-2)" "unprognostic (2.55e-2)" "unprognostic (1.10e-1)" "unprognostic (1.95e-1)" "unprognostic (2.89e-1)" "unprognostic (5.84e-2)" 21.9 27.6 15.9 20.1 20.0 19.4 25.4 18.3 21.7 19.7 11.9 24.0 21.8 22.6 22.3 29.1 21.0 19.8 14.5 16.2 14.7 30.0 27.4 17.9 25.1 11.0 13.3 25.4 15.1 21.0 17.2 29.4 12.8 22.5 31.8 17.8 20.6 31.1 11.0 19.7 19.8 29.3 14.6 19.2 24.2 15.3 16.5 22.9 29.5 27.4 29.4 27.4 17.4 23.1 62.4 81.0 47.5 47.9 71.3 68.0 85.4 80.2 60.9 67.9 93.1 118.7 92.1 39.9 50.6 58.8 104.1 59.9 69.7 81.9 103.3 49.7 47.8 78.2 112.3 112.3 98.8 80.7 56.1 51.7 75.4 83.2 107.5 60.2 94.8 39.1 79.7 57.2 55.5 106.7 43.5 63.5 68.2 121.4 59.8 52.4 58.4 56.7 78.6 94.7 56.6 31.4 70.2 63.7 52.3 85.6 54.4 85.2 80.0 96.7 66.9 47.5 73.8 31.9 49.5 88.6 69.6 76.0 62.5 20.2 40.2 19.1 23.1 51.0 19.8 20.2 17.7 21.7 69.5 21.6 23.4 21.0 3.7 77.2 34.8 25.4 26.7 28.8 15.9 20.0 18.3 21.7 16.2 14.7 11.0 13.3 12.8 14.6 16.5 23.1 14.9 6.4 7.5 14.4 13.1 16.6 15.2 21.6 13.1 13.2 13.2 10.3 6.2 10.0 20.1 18.4 20.9 35.4 18.1 14.0 31.3 24.5 10.7 13.5 17.4 14.3 10.2 17.2 61.9 17.5 42.8 17.4 14.3 11.2 6.3 18.1 18.2 17.5 37.0 10.1 44.7 14.6 14.2 19.4 45.8 11.8 11.1 17.2 14.2 15.0 19.7 8.9 26.8 27.2 39.2 19.4 11.6 14.7 12.2 19.9 14.2 48.6 15.9 12.7 6.6 11.1 16.1 14.7 17.4 20.1 20.3 25.6 10.5 24.8 21.3 14.8 RPEL1 ENSG00000235376 "Ribulose-5-phosphate-3-epimerase like 1" Q2QD12 10 103245887-103248016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Isomerase "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Cell type enhanced" "Detected in some" "Bipolar cells: 3.1;Cone photoreceptor cells: 8.4;Ionocytes: 2.0;Rod photoreceptor cells: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA036498, HPA036499" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 9: Photoreceptor cells - Phototransduction" Cytosol "Nucleoplasm, Plasma membrane" "HPA036498: AB_2675157, HPA036499: AB_10670109" "unprognostic (7.52e-2)" "unprognostic (1.69e-1)" "unprognostic (4.78e-2)" "unprognostic (1.54e-1)" "unprognostic (1.45e-1)" "unprognostic (1.83e-1)" "unprognostic (6.01e-2)" "unprognostic (1.15e-1)" "unprognostic (8.91e-2)" "unprognostic (6.59e-2)" "unprognostic (4.34e-1)" "unprognostic (1.14e-1)" "unprognostic (5.69e-2)" "unprognostic (1.62e-1)" "unprognostic (6.72e-2)" "unprognostic (5.06e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.2 0.0 3.1 0.0 0.0 1.9 0.0 0.7 0.0 8.4 0.3 1.3 0.5 0.0 0.5 0.1 0.1 0.0 0.3 1.8 0.0 0.6 0.2 0.5 0.7 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.0 0.6 0.5 2.0 0.0 1.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.5 0.1 0.2 4.4 0.0 0.0 0.4 0.1 0.3 0.0 0.3 0.4 0.1 0.0 0.7 0.0 RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 40.5;Excitatory neurons: 59.8;Respiratory ciliated cells: 85.9;Spermatocytes: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA039405: AB_10794636, HPA040530: AB_2677023" "prognostic unfavorable (6.93e-4)" "unprognostic (1.52e-1)" "unprognostic (2.19e-3)" "unprognostic (2.26e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-4)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (5.22e-3)" "unprognostic (1.52e-1)" "unprognostic (4.92e-4)" "unprognostic (5.95e-2)" 1.6 3.5 2.3 2.1 2.2 1.5 3.2 1.0 5.2 3.1 9.5 1.7 1.3 3.8 3.7 2.2 6.8 2.7 1.9 2.7 3.0 3.0 1.1 1.9 1.8 2.4 3.2 3.5 2.0 7.6 6.0 2.1 1.9 2.9 1.7 2.9 1.7 2.8 1.0 1.9 0.9 3.5 1.0 0.9 1.9 13.5 3.5 2.6 4.6 1.4 1.8 2.2 1.8 3.2 11.8 13.7 11.6 10.7 13.9 13.3 5.6 12.7 7.9 9.8 2.7 7.1 9.5 7.5 8.5 11.1 7.8 12.5 9.4 11.6 19.1 4.6 7.2 2.8 12.1 7.5 6.0 6.7 5.0 8.1 6.9 11.4 6.9 11.4 8.9 10.0 7.2 4.3 14.8 4.5 11.2 4.7 7.4 3.7 6.3 19.3 15.9 9.4 14.0 3.1 19.9 7.5 14.3 6.4 5.3 6.7 10.0 5.7 7.8 12.2 8.6 9.7 11.0 5.4 6.9 13.1 18.9 3.9 7.3 0.7 0.2 0.3 1.2 0.3 1.2 1.1 0.8 1.0 0.2 1.5 0.8 1.8 0.6 0.8 0.3 0.7 0.7 0.4 2.3 2.2 1.0 5.2 2.7 3.0 2.4 3.2 1.9 1.0 3.5 3.2 3.1 6.4 4.8 15.7 2.9 4.6 2.8 11.1 4.6 5.5 6.9 8.0 9.8 1.5 15.1 11.0 8.4 5.5 1.5 1.3 17.6 7.4 21.5 40.5 20.7 3.9 0.0 3.0 59.8 3.3 7.4 12.9 5.1 8.6 7.0 12.9 2.5 3.8 2.9 3.3 36.6 5.6 4.1 1.2 3.1 12.0 4.7 1.9 1.8 9.4 1.8 6.3 2.1 14.1 8.6 3.3 0.5 6.4 2.1 1.7 0.2 19.8 85.9 8.7 6.6 7.8 9.7 43.2 11.2 4.7 5.4 1.6 2.7 11.5 4.4 2.4 RPIA ENSG00000153574 "Ribose 5-phosphate isomerase A" P49247 2 88691673-88750929 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Neuropathy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 89.6" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 234.3;Erythroid cells: 167.9;Syncytiotrophoblasts: 225.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042620, HPA057954" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA 2500000 "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Vesicles, Plasma membrane" "HPA042620: AB_10793980, HPA057954: AB_2683563" "unprognostic (3.35e-2)" "unprognostic (1.35e-2)" "unprognostic (6.96e-2)" "unprognostic (9.24e-2)" "unprognostic (4.31e-1)" "unprognostic (8.24e-2)" "prognostic unfavorable (1.46e-5)" "unprognostic (2.73e-3)" "unprognostic (1.82e-3)" "unprognostic (8.70e-2)" "unprognostic (8.82e-2)" "unprognostic (2.79e-1)" "prognostic unfavorable (8.53e-6)" "unprognostic (3.47e-2)" "unprognostic (2.53e-1)" "unprognostic (1.01e-2)" "unprognostic (8.79e-3)" 17.2 11.0 7.4 19.6 7.6 89.6 16.0 8.3 8.9 13.4 8.0 22.7 22.1 13.2 9.5 24.1 14.6 11.7 16.0 7.3 8.2 10.6 7.8 12.2 28.0 7.8 7.5 13.7 17.9 7.4 8.2 33.8 7.5 8.9 23.0 4.1 15.9 8.1 29.9 11.9 18.9 12.5 7.8 19.2 18.9 9.6 8.0 40.4 9.7 17.1 32.4 16.5 12.5 7.9 29.7 17.0 33.7 26.9 23.4 23.9 73.8 16.1 15.1 26.1 17.8 61.1 38.2 150.1 34.3 18.7 35.8 17.7 42.4 13.5 40.9 71.9 55.3 60.2 11.0 60.7 23.7 111.5 42.4 22.1 11.2 23.3 35.9 13.0 37.4 78.7 65.7 25.3 24.8 46.5 123.4 97.2 30.7 97.6 27.7 63.5 40.1 36.8 21.7 47.1 24.0 27.4 19.4 24.8 39.3 18.3 13.5 45.3 21.4 15.5 40.7 51.2 46.7 19.7 17.2 149.3 15.9 99.4 22.5 10.6 16.0 36.4 16.9 16.7 21.4 31.4 23.5 25.1 22.7 23.5 33.4 27.8 3.9 21.9 21.9 10.9 22.0 20.6 7.4 7.6 8.3 8.9 7.3 8.2 7.8 7.5 7.5 7.8 8.0 7.9 38.9 12.8 13.2 4.6 43.2 37.3 21.3 31.2 21.6 8.7 22.2 18.2 13.7 14.3 22.7 20.2 2.1 234.3 37.1 20.6 9.8 21.7 8.1 28.0 23.3 35.0 19.2 167.9 13.3 34.2 98.9 23.5 31.1 43.2 21.6 30.7 24.3 7.1 43.8 13.5 15.7 26.9 26.4 23.1 33.9 4.0 19.9 23.7 40.9 11.2 32.4 5.2 60.8 13.6 13.3 22.8 28.1 18.8 35.8 41.7 20.6 18.7 10.1 4.8 19.7 19.8 18.0 28.4 33.4 37.6 40.9 225.6 38.8 37.8 58.5 43.7 RPL36A "L36A, RPL44" ENSG00000241343 "Ribosomal protein L36a" P83881 X 101390824-101396155 "Metabolic proteins, Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 3019.1;Undifferentiated cells: 3021.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2852.7" "Low region specificity" "Detected in all" "HPA063979, HPA077586" Uncertain Supported "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA063979: AB_2685164, HPA077586: AB_2686846" "unprognostic (3.38e-2)" "unprognostic (2.11e-2)" "unprognostic (7.04e-2)" "unprognostic (2.06e-1)" "unprognostic (1.02e-2)" "unprognostic (4.19e-3)" "unprognostic (4.15e-3)" "unprognostic (1.28e-1)" "unprognostic (2.86e-2)" "unprognostic (2.77e-1)" "unprognostic (2.19e-2)" "unprognostic (8.17e-2)" "prognostic unfavorable (8.81e-11)" "unprognostic (1.87e-2)" "unprognostic (4.50e-3)" "unprognostic (3.57e-3)" "unprognostic (4.06e-2)" 1674.1 1002.0 390.2 179.6 390.9 502.0 1779.0 387.0 608.7 1862.0 390.9 1384.5 163.9 1291.5 278.5 1823.7 1542.2 94.6 878.4 384.9 392.9 1127.4 829.5 1066.3 304.6 398.8 389.8 3553.5 2580.0 160.2 799.7 230.4 393.6 1347.0 290.4 94.6 1304.2 219.6 1546.0 2491.5 1369.6 209.8 398.2 1575.2 1319.0 266.3 391.9 430.4 981.5 224.1 502.0 1430.5 1751.0 405.9 508.3 1045.1 465.5 237.5 640.1 1232.0 273.6 198.9 532.7 642.1 1017.6 1196.0 360.1 571.6 367.5 318.1 399.5 350.5 727.8 641.2 651.0 309.1 1445.2 205.8 1919.5 1159.3 803.0 413.1 364.3 985.5 1395.8 436.6 895.6 931.0 576.9 563.1 486.8 660.7 546.2 2852.7 288.5 1285.4 583.8 1637.7 1118.7 367.7 384.8 863.5 633.5 811.3 314.8 508.8 116.8 506.3 608.3 459.4 238.4 806.3 187.0 206.4 369.8 477.2 350.9 330.0 475.0 470.0 223.6 749.5 240.3 130.7 562.7 109.4 608.3 591.8 1102.4 1242.0 1212.6 866.9 814.7 957.9 1322.5 1179.8 51.0 760.6 615.8 919.8 678.7 1804.2 390.2 390.9 387.0 608.7 384.9 392.9 398.8 389.8 393.6 398.2 391.9 405.9 309.5 439.1 987.0 0.0 1100.1 917.4 432.3 574.6 595.8 28.9 1600.3 970.8 16.1 885.0 946.8 174.7 14.6 762.3 615.9 641.2 434.3 1235.1 9.4 124.9 331.6 566.0 1100.8 1215.5 0.0 3019.1 1125.2 523.5 315.0 164.3 1272.4 137.9 1387.8 738.4 609.1 15.2 0.0 2744.0 183.1 2089.7 1144.3 49.3 1055.9 565.6 524.7 0.0 1620.0 187.9 710.6 0.0 0.0 2338.4 1805.5 418.6 559.4 350.6 1349.6 611.7 329.9 41.2 236.7 512.1 467.7 28.7 99.3 758.7 1122.1 751.4 875.8 153.1 3021.8 351.4 RPL36A-HNRNPH2 ENSG00000257529 "RPL36A-HNRNPH2 readthrough" X 101391011-101412297 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 12.8;Alveolar cells type 2: 39.9;Club cells: 29.1;Fibroblasts: 8.8;granulocytes: 27.8;Respiratory ciliated cells: 18.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (3.69e-1)" "unprognostic (1.44e-2)" "unprognostic (2.91e-1)" "unprognostic (4.65e-3)" "unprognostic (1.63e-1)" "unprognostic (2.96e-1)" "unprognostic (1.79e-1)" "unprognostic (5.34e-2)" "unprognostic (2.27e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (1.49e-3)" "unprognostic (2.04e-4)" "unprognostic (1.56e-1)" "unprognostic (4.81e-2)" "unprognostic (3.94e-1)" 155.5 114.7 141.9 147.6 149.9 473.9 371.3 140.5 211.3 169.5 142.0 178.1 120.3 131.9 91.3 82.4 124.0 56.9 68.9 139.2 147.0 103.1 136.9 84.1 206.9 145.8 140.6 430.7 198.7 116.1 0.3 117.0 146.1 111.6 133.6 38.7 163.1 96.2 194.2 115.9 142.0 89.7 152.1 149.1 138.2 32.9 147.3 348.5 82.7 188.2 223.7 208.3 0.5 153.8 479.9 63.6 351.8 196.0 556.6 603.8 207.1 411.5 307.5 363.4 528.3 37.6 249.6 1272.3 379.1 379.3 282.1 312.4 692.9 639.6 308.0 494.4 334.8 589.7 99.9 58.4 726.0 839.5 372.7 837.9 498.0 458.3 744.0 628.2 359.2 413.5 590.6 507.6 266.5 119.0 364.7 535.8 425.9 1038.7 262.3 388.8 984.7 647.3 412.1 29.5 230.9 445.6 512.1 373.3 416.7 288.6 171.7 707.0 594.4 115.8 314.9 330.7 357.0 374.5 651.9 710.4 186.8 1188.4 141.9 97.1 324.6 105.0 284.3 334.8 348.1 373.2 363.3 332.4 450.1 354.6 364.2 357.9 57.5 277.5 292.2 306.2 274.4 605.1 141.9 149.9 140.5 211.3 139.2 147.0 145.8 140.6 146.1 152.1 147.3 153.8 0.0 12.8 39.9 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.5 0.0 0.0 8.8 0.0 0.0 27.8 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 RPL36AL RPL36A ENSG00000165502 "Ribosomal protein L36a like" Q969Q0 14 49618530-49620626 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" HPA077586 Approved "Endoplasmic reticulum,Plasma membrane,Cytosol" NA Yes "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Plasma membrane" "HPA077586: AB_2686846" "unprognostic (1.55e-2)" "unprognostic (2.44e-2)" "unprognostic (8.73e-2)" "unprognostic (3.15e-3)" "unprognostic (1.52e-1)" "unprognostic (2.55e-2)" "unprognostic (1.31e-1)" "unprognostic (6.37e-2)" "unprognostic (4.18e-2)" "unprognostic (1.38e-3)" "unprognostic (2.29e-1)" "unprognostic (4.72e-1)" "unprognostic (1.16e-3)" "unprognostic (8.32e-2)" "unprognostic (2.80e-1)" "prognostic favorable (2.83e-4)" "unprognostic (1.00e-1)" 279.7 310.9 234.2 246.4 241.7 404.2 328.6 232.1 349.8 381.8 221.4 331.8 260.5 280.7 492.7 277.4 315.9 162.6 273.2 225.1 244.6 255.3 372.3 240.5 311.9 244.4 237.3 501.3 628.8 220.0 252.9 176.7 240.6 250.8 248.8 102.0 327.5 253.2 378.6 247.6 284.9 197.9 242.0 294.2 360.3 137.6 240.5 283.4 211.2 206.5 377.1 297.8 285.9 246.2 635.8 473.9 330.1 192.6 471.3 649.8 194.9 508.9 569.9 475.4 534.7 499.0 426.1 833.4 474.5 430.3 327.9 443.5 287.6 441.3 554.8 288.1 331.1 521.6 527.5 652.8 595.1 838.8 426.0 667.8 668.2 362.7 485.9 553.7 614.6 367.3 339.5 714.4 372.8 831.7 496.5 752.6 186.0 452.1 482.0 308.6 519.5 449.5 730.7 964.2 290.3 178.1 448.5 350.8 544.1 313.0 762.2 460.1 468.2 291.3 463.0 382.3 399.8 427.6 487.0 842.7 210.5 376.9 283.7 1308.9 603.0 935.1 823.8 582.2 1113.2 959.3 1070.1 1040.5 614.8 729.1 984.7 937.6 654.0 806.3 542.2 1008.3 1096.2 1506.1 234.2 241.7 232.1 349.8 225.1 244.6 244.4 237.3 240.6 242.0 240.5 246.2 453.2 307.7 395.4 11.4 666.4 945.7 1352.2 1151.7 422.3 110.9 674.6 1022.1 662.4 652.0 643.5 312.6 25.0 690.0 778.0 871.5 995.9 739.8 614.3 490.0 431.4 515.5 366.2 535.9 14.1 1371.2 720.9 523.6 381.3 543.7 716.4 369.2 591.8 920.1 778.5 80.8 16.0 793.7 520.8 814.1 1020.0 236.4 725.7 585.0 843.1 22.5 1045.3 368.1 930.0 11.6 22.9 1311.2 1063.8 534.1 853.2 1279.2 1151.2 1194.4 579.1 127.7 486.4 693.6 898.3 364.7 150.2 390.6 839.3 516.3 888.1 355.4 620.5 1412.3 RPSA "37LRP, LAMR1, LRP, p40, SA" ENSG00000168028 "Ribosomal protein SA" P08865 3 39406716-39412542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor, Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB009561 Approved Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB009561: AB_2182543" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (3.97e-2)" "unprognostic (3.72e-2)" "unprognostic (5.38e-2)" "unprognostic (5.10e-2)" "unprognostic (5.84e-3)" "unprognostic (2.54e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (8.56e-2)" "unprognostic (7.50e-2)" "unprognostic (2.91e-2)" "unprognostic (3.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" 1063.0 929.1 813.4 685.7 824.8 1574.8 1068.4 782.0 979.1 1260.0 761.8 1158.4 605.8 1022.1 351.0 1922.5 1128.3 372.5 783.9 778.6 794.3 905.9 972.5 894.3 1281.4 817.8 809.6 2153.7 2616.3 605.5 813.4 468.8 812.9 1212.6 872.2 273.3 1039.7 446.9 1087.1 1529.4 1133.1 718.3 842.4 1525.8 1209.3 358.0 831.9 1259.9 862.6 730.4 1466.4 1127.5 1293.1 821.5 1800.4 1646.5 1367.5 2265.9 1203.3 2661.2 2155.0 1251.2 2005.9 2775.9 1611.8 1811.6 1513.7 3949.6 737.0 2535.3 747.6 695.4 2983.8 2945.7 2402.3 1459.6 1599.6 1783.6 1390.5 1750.2 2322.7 2546.4 1649.2 3043.3 4729.8 2147.2 3475.3 2030.8 2942.7 2343.5 1909.3 1883.8 2031.1 1282.1 3031.0 1960.4 4574.2 2756.9 2755.1 1412.2 1958.4 2974.8 2004.4 814.2 985.3 1989.0 674.8 5156.5 2202.9 1843.5 1509.0 3544.5 1156.6 845.2 1545.8 1422.3 3102.3 1440.6 2363.4 2437.5 1355.7 2481.7 1143.9 98.3 240.5 56.7 572.9 294.6 993.1 1010.3 942.1 758.8 654.2 951.8 1036.2 936.1 34.3 726.0 247.5 723.6 765.5 1499.7 813.4 824.8 782.0 979.1 778.6 794.3 817.8 809.6 812.9 842.4 831.9 821.5 532.1 519.2 800.2 10.7 2802.5 1802.5 2606.9 1585.5 2040.3 270.4 1864.7 1423.4 64.0 1095.2 906.4 325.5 95.9 2852.5 1768.9 625.4 992.0 1598.4 144.3 536.7 1178.5 891.2 1033.6 1733.9 21.3 3417.4 4473.1 927.1 821.6 747.7 778.4 1654.5 937.3 717.7 1608.4 173.3 21.5 1847.0 455.7 1304.9 1469.6 283.7 1240.5 1086.9 738.2 12.2 1605.2 621.1 1858.9 19.1 29.3 1889.5 1184.2 747.4 1501.8 2136.7 724.4 1257.1 476.2 364.4 473.3 1053.5 1002.2 352.2 1255.8 2879.8 1916.2 2420.7 2100.0 1539.2 2442.4 2884.6 RPUSD1 "C16orf40, MGC19600, RLUCL" ENSG00000007376 "RNA pseudouridine synthase domain containing 1" Q9UJJ7 16 784974-788397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041144, HPA041938" Approved Approved "Nucleoplasm,Golgi apparatus,Cell Junctions,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 56: Bipolar cells - Visual perception" "Golgi apparatus" "Nucleoplasm, Cell Junctions, Cytosol" "HPA041144: AB_10794265, HPA041938: AB_10795601" "unprognostic (1.51e-2)" "unprognostic (1.26e-3)" "unprognostic (2.03e-1)" "unprognostic (4.01e-1)" "unprognostic (2.99e-1)" "unprognostic (9.05e-3)" "unprognostic (1.07e-3)" "unprognostic (3.45e-2)" "unprognostic (1.08e-1)" "unprognostic (3.31e-1)" "unprognostic (2.04e-1)" "unprognostic (1.23e-1)" "unprognostic (6.25e-2)" "unprognostic (8.07e-3)" "unprognostic (5.44e-2)" "unprognostic (2.95e-1)" "unprognostic (1.41e-1)" 11.8 12.9 12.3 9.7 11.9 13.5 12.0 11.2 21.1 11.0 6.8 14.9 9.8 13.1 3.1 18.7 10.6 4.7 12.0 12.5 10.0 13.0 15.3 9.5 11.3 12.9 10.7 9.2 16.1 4.5 11.2 4.2 10.9 14.6 2.5 2.2 15.2 5.1 11.2 18.1 15.6 3.6 9.7 21.9 17.0 7.2 12.4 8.3 11.0 3.1 5.3 13.1 11.8 11.6 28.2 32.5 7.8 35.7 6.8 7.9 36.2 22.9 13.0 29.4 21.3 76.4 25.8 38.9 24.3 11.1 20.6 47.2 18.1 23.1 5.3 35.7 74.0 19.2 52.1 28.0 10.9 35.8 31.1 11.7 21.9 25.4 6.7 8.7 20.4 22.6 45.7 17.1 10.2 89.2 44.8 37.4 40.0 13.0 55.4 79.0 21.0 80.5 10.9 17.0 40.8 29.4 26.4 42.7 26.1 4.6 22.0 43.9 23.3 29.1 37.9 30.9 33.6 27.2 29.6 45.7 14.1 27.8 24.5 16.5 14.8 13.7 12.7 13.7 12.6 10.2 10.7 14.1 17.0 12.0 10.7 11.1 9.2 13.4 13.6 15.8 14.8 13.1 12.3 11.9 11.2 21.1 12.5 10.0 12.9 10.7 10.9 9.7 12.4 11.6 9.4 3.2 3.3 3.6 12.9 15.9 3.5 13.2 10.8 42.0 12.8 13.3 4.4 5.7 5.2 9.2 2.1 20.5 13.7 23.0 7.9 19.5 0.4 4.7 7.1 8.1 13.2 6.3 6.0 26.9 25.7 6.8 17.9 8.2 0.0 10.9 9.3 5.1 19.6 1.7 4.2 11.5 10.2 5.7 7.0 1.8 6.8 9.0 14.2 1.9 19.2 11.1 23.7 1.5 3.5 29.9 16.6 6.4 19.5 6.3 21.1 10.2 3.4 3.8 13.1 3.6 9.4 3.6 11.4 11.5 16.8 14.6 11.9 13.3 20.7 5.0 RRAD "RAD, REM3" ENSG00000166592 "RRAD, Ras related glycolysis inhibitor and calcium channel regulator" P55042 16 66921679-66925536 "Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "heart muscle: 305.8;skeletal muscle: 769.7" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 302.0;Endometrial ciliated cells: 477.6;Glandular and luminal cells: 245.5;Respiratory ciliated cells: 214.9;Skeletal myocytes: 179.2;Smooth muscle cells: 232.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 9 "HDLM-2: 194.2;U-87 MG: 51.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041755 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA041755: AB_2677655" "unprognostic (1.40e-2)" "unprognostic (2.78e-2)" "unprognostic (9.77e-2)" "unprognostic (3.84e-2)" "unprognostic (1.36e-2)" "unprognostic (1.11e-1)" "unprognostic (3.74e-2)" "unprognostic (2.37e-1)" "unprognostic (1.66e-1)" "unprognostic (2.46e-2)" "unprognostic (2.12e-2)" "unprognostic (1.08e-1)" "unprognostic (2.06e-3)" "unprognostic (3.46e-2)" "unprognostic (3.33e-2)" "unprognostic (2.04e-2)" "unprognostic (4.80e-3)" 56.5 18.1 4.1 5.5 6.4 4.7 24.4 16.8 14.6 34.6 12.0 16.3 3.4 21.0 1.7 101.2 35.2 11.9 305.8 5.0 5.3 45.0 5.1 52.3 4.0 4.2 6.0 18.8 2.5 1.7 14.4 32.6 4.2 18.4 1.1 2.5 29.4 3.5 769.7 19.9 10.9 6.3 4.9 2.8 13.9 6.7 5.6 1.7 13.7 28.3 3.2 27.4 32.9 6.3 0.1 8.5 0.2 0.1 0.0 0.8 0.3 4.9 0.5 0.8 4.2 2.2 5.9 0.2 4.8 0.3 1.5 0.4 0.2 0.3 0.7 194.2 0.3 0.0 0.3 2.1 8.0 0.0 0.6 2.3 0.9 14.3 0.2 3.3 0.0 0.1 0.2 3.8 0.6 0.2 0.0 0.5 0.7 0.0 0.3 0.6 0.2 0.0 0.9 0.1 0.3 0.6 4.5 0.0 0.0 0.7 0.0 0.5 0.0 0.4 0.5 0.3 0.4 6.2 0.2 0.5 51.9 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 6.4 16.8 14.6 5.0 5.3 4.2 6.0 4.2 4.9 5.6 6.3 17.0 70.5 150.0 3.3 33.6 9.4 3.7 11.3 4.0 21.4 10.7 15.9 302.0 0.0 18.9 68.0 10.4 4.1 22.5 9.7 23.5 47.4 1.6 477.6 36.7 18.1 10.7 0.0 0.8 3.2 8.2 39.4 10.7 245.5 34.2 26.4 0.7 0.0 1.4 1.7 1.0 7.8 14.2 1.9 36.2 0.7 0.6 24.6 23.2 1.9 0.6 2.4 0.0 0.5 0.6 55.3 5.0 5.3 59.5 30.7 3.4 11.3 214.9 3.2 111.7 179.2 232.6 1.7 5.2 148.1 10.1 5.6 12.4 0.5 6.9 2.6 RRP12 KIAA0690 ENSG00000052749 "Ribosomal RNA processing 12 homolog" Q5JTH9 10 97356358-97426076 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 90.9;skeletal muscle: 38.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 26.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049945, HPA074403" Supported "Nucleoli,Vesicles,Plasma membrane,Cytosol" No No "Cluster 51: Monocytes - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoli "Vesicles, Plasma membrane, Cytosol" "HPA049945: AB_2680965, HPA074403: " "unprognostic (2.79e-1)" "unprognostic (7.65e-2)" "unprognostic (5.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.42e-1)" "unprognostic (1.73e-1)" "prognostic unfavorable (3.12e-8)" "unprognostic (2.64e-1)" "unprognostic (1.30e-2)" "unprognostic (1.54e-1)" "unprognostic (3.94e-2)" "unprognostic (1.82e-1)" "prognostic unfavorable (2.54e-5)" "unprognostic (2.58e-2)" "unprognostic (3.32e-1)" "unprognostic (4.81e-2)" "unprognostic (6.99e-3)" 8.1 10.2 2.6 9.2 3.4 90.9 5.6 1.1 7.6 5.6 2.4 4.9 6.0 7.4 3.6 8.5 7.3 7.2 11.4 3.2 2.7 6.8 5.7 6.7 6.7 4.3 4.4 6.1 16.0 9.3 10.2 4.3 4.1 6.3 3.8 3.4 8.3 4.0 38.5 10.3 4.7 6.0 0.2 7.6 6.3 10.9 3.7 4.7 5.5 9.7 6.1 9.3 5.7 4.6 38.9 50.8 13.2 28.6 10.0 11.6 28.9 24.2 14.4 24.2 18.7 55.6 35.0 42.3 30.4 15.1 21.6 48.7 36.3 28.0 16.3 23.1 44.2 32.8 19.5 43.6 16.5 51.7 41.5 12.2 38.6 59.9 54.6 27.0 13.7 23.5 47.7 27.4 14.0 50.8 35.0 33.0 57.0 20.4 34.0 38.1 18.0 42.1 16.8 21.4 17.7 37.9 19.2 18.1 24.1 10.4 43.7 26.5 18.2 16.1 27.9 36.5 76.4 55.7 52.7 48.6 23.2 64.9 17.9 0.4 11.2 6.9 2.7 13.6 3.3 3.9 1.6 2.2 6.2 4.2 2.5 2.8 26.7 1.9 16.9 5.0 1.2 6.0 2.6 3.4 1.1 7.6 3.2 2.7 4.3 4.4 4.1 0.2 3.7 4.6 8.8 35.3 31.1 5.9 18.5 23.5 14.2 5.1 25.0 5.8 12.7 9.9 11.6 7.2 21.5 14.7 41.7 5.2 7.7 10.6 0.0 8.7 7.2 17.1 10.6 10.6 21.5 7.2 15.1 8.7 7.5 13.5 27.0 20.1 41.7 12.9 3.9 8.9 11.5 5.0 9.5 13.8 4.1 12.5 7.1 4.8 3.7 30.3 7.2 2.8 12.3 1.9 3.1 5.0 4.4 8.5 6.4 2.6 31.8 17.1 3.7 6.8 24.6 12.7 0.0 19.4 6.7 10.6 20.6 22.7 19.6 9.2 11.0 13.5 11.5 13.6 RRP7A "CGI-96, Rrp7" ENSG00000189306 "Ribosomal RNA processing 7 homolog A" Q9Y3A4 22 42508344-42519796 "Plasma proteins, Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001586, HPA046768" Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Nucleoli" "Cell Junctions" "HPA001586: AB_1078506, HPA046768: AB_2679796" "unprognostic (8.46e-2)" "unprognostic (3.30e-3)" "unprognostic (5.96e-2)" "unprognostic (3.21e-3)" "unprognostic (9.71e-3)" "unprognostic (2.92e-1)" "prognostic unfavorable (1.21e-5)" "unprognostic (6.73e-2)" "unprognostic (3.00e-1)" "unprognostic (2.28e-1)" "unprognostic (2.41e-1)" "unprognostic (3.22e-2)" "unprognostic (9.53e-3)" "unprognostic (8.02e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-2)" "unprognostic (1.71e-2)" 14.0 16.5 15.8 9.8 18.0 12.3 15.4 14.3 17.0 13.9 11.6 13.9 6.2 13.7 28.2 18.7 13.9 4.7 15.6 16.4 14.1 22.3 18.4 13.0 14.2 15.0 15.3 17.3 14.5 11.1 11.2 6.6 15.5 22.3 6.1 5.2 15.6 7.5 13.8 15.7 13.8 6.4 13.1 18.4 15.0 12.8 14.6 10.3 13.6 5.2 10.2 14.8 14.0 15.7 23.9 34.6 21.1 24.7 13.7 8.8 35.9 21.0 13.7 27.0 22.8 47.4 14.3 41.4 10.6 15.5 13.4 29.3 25.4 28.1 11.1 11.2 50.3 21.8 26.4 23.6 11.2 57.1 19.4 12.1 16.4 35.6 17.7 10.5 15.6 21.6 30.7 12.1 15.9 51.5 54.8 23.0 17.9 20.5 25.5 88.9 19.9 17.6 13.7 31.5 9.8 8.4 14.8 50.5 20.7 8.9 18.2 23.9 12.4 22.9 25.1 16.4 21.1 18.5 16.0 48.8 18.2 20.3 31.2 16.1 28.0 22.4 21.2 33.2 20.4 26.1 18.4 19.7 21.8 32.5 20.0 18.8 5.7 20.4 37.2 37.6 17.1 26.2 15.8 18.0 14.3 17.0 16.4 14.1 15.0 15.3 15.5 13.1 14.6 15.7 32.2 22.4 36.6 5.9 48.6 43.8 95.1 41.4 12.5 26.6 28.6 28.3 16.0 31.5 37.2 22.0 16.7 93.0 50.3 48.4 17.6 71.3 55.8 24.2 25.4 38.6 26.4 64.6 7.5 27.2 133.8 31.0 34.7 28.8 47.5 46.3 37.5 32.6 94.8 26.9 6.8 39.8 28.5 43.3 47.4 118.3 22.1 39.5 33.8 6.5 116.5 24.8 68.0 1.0 7.9 52.1 46.0 18.4 51.4 94.3 38.5 42.1 34.4 28.5 6.6 30.2 37.0 33.5 24.7 27.3 37.8 120.4 40.2 45.2 59.4 106.3 RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 349.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 60.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane" "HPA020406: AB_1856488, HPA020413: AB_2253910" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (2.43e-2)" "prognostic favorable (3.74e-4)" "unprognostic (1.27e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (9.02e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.53e-3)" 7.3 6.4 8.7 11.5 9.1 8.2 12.1 19.0 12.1 10.3 10.2 11.3 9.0 12.5 10.3 10.8 9.5 7.3 5.6 8.5 10.5 9.1 11.3 10.5 16.1 8.2 9.0 14.5 11.2 10.3 6.9 9.9 8.6 10.3 11.7 30.2 9.6 11.4 8.2 7.8 10.4 11.0 9.0 15.0 11.0 26.3 8.6 18.3 16.5 7.6 15.0 9.6 8.2 11.6 15.8 11.9 19.6 34.5 13.4 17.0 9.5 11.5 12.4 16.0 18.2 14.9 27.6 32.4 4.4 12.0 20.2 13.4 26.8 15.0 22.8 17.7 14.4 25.8 18.4 14.7 11.3 32.1 23.3 12.2 10.7 14.7 16.0 12.1 13.5 21.2 35.7 33.0 16.8 18.2 27.7 32.1 14.0 20.3 10.6 28.3 19.6 34.2 10.0 20.5 22.9 24.0 17.5 31.4 12.6 19.9 19.2 16.9 12.9 23.9 21.9 14.5 17.7 14.7 16.7 51.6 11.4 29.2 16.0 21.6 7.4 13.5 9.5 5.8 7.3 11.0 8.4 7.1 4.4 13.5 7.8 8.6 60.6 6.4 6.7 13.9 9.3 2.6 8.7 9.1 19.0 12.1 8.5 10.5 8.2 9.0 8.6 9.0 8.6 11.6 53.6 57.7 60.3 27.1 85.0 78.8 102.1 76.1 88.8 246.8 52.1 57.3 22.1 61.5 84.4 55.2 235.6 52.7 101.5 77.1 39.2 38.1 271.3 55.5 63.3 60.8 77.5 47.7 44.3 50.4 34.1 55.6 51.5 45.6 70.3 51.3 49.2 56.5 43.7 158.2 47.5 104.6 57.0 48.1 69.0 85.2 101.5 46.4 64.0 34.7 59.0 83.2 132.8 53.8 50.1 35.1 62.7 119.6 74.6 56.7 49.6 28.4 72.0 349.9 72.3 44.2 73.0 108.0 156.7 56.2 75.3 38.7 90.2 61.7 79.1 84.0 RSC1A1 RS1 ENSG00000215695 "Regulator of solute carriers 1" Q92681 1 15659869-15661722 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027813, HPA028676" Approved Supported "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Cell Junctions" "HPA027813: AB_10600308, HPA028676: AB_10600895" 3.0 1.5 0.1 2.6 0.3 4.1 1.9 0.4 1.1 1.3 1.1 1.4 0.5 1.9 0.3 4.2 1.9 1.9 3.0 0.4 0.0 4.6 8.3 2.3 2.9 0.6 0.0 1.9 1.1 2.9 0.5 3.2 0.6 2.0 2.0 2.4 0.2 1.4 0.2 0.8 1.4 3.7 0.3 0.8 1.3 2.4 0.6 2.0 2.4 4.9 4.1 2.2 1.0 1.7 4.1 4.7 5.7 3.8 6.9 4.8 7.5 3.4 5.6 9.2 8.5 7.8 6.5 9.2 3.2 7.6 4.6 2.8 14.9 4.8 11.2 6.0 3.8 8.5 9.1 8.4 1.6 12.6 4.2 3.8 0.0 15.8 8.7 2.2 5.9 6.1 23.6 8.3 6.8 4.1 6.7 0.0 6.2 2.4 2.7 5.6 8.0 3.8 2.2 7.5 4.6 1.9 6.3 2.9 4.9 4.8 4.0 1.1 5.8 4.7 8.5 4.2 2.5 2.6 5.2 15.6 1.9 3.4 3.4 0.0 0.4 0.1 0.1 0.9 0.4 0.3 0.1 0.6 0.9 0.0 0.2 0.1 0.0 0.4 0.0 0.2 0.7 0.5 0.1 0.3 0.4 1.1 0.4 0.0 0.6 0.0 0.6 0.3 0.6 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RSKR "FLJ25006, SgK494" ENSG00000167524 "Ribosomal protein S6 kinase related" 17 28601827-28614197 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.8" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 7.1;Extravillous trophoblasts: 2.4;Hofbauer cells: 4.1;Syncytiotrophoblasts: 24.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in some" "Low region specificity" "Detected in many" HPA046590 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Vesicles, Plasma membrane" Nucleoplasm "HPA046590: AB_2679710" "unprognostic (1.83e-1)" "unprognostic (9.42e-2)" "unprognostic (2.84e-2)" "unprognostic (2.30e-2)" "unprognostic (2.11e-1)" "unprognostic (2.06e-3)" "unprognostic (9.33e-3)" "unprognostic (2.63e-1)" "unprognostic (8.62e-4)" "unprognostic (2.09e-2)" "unprognostic (6.81e-2)" "unprognostic (3.45e-5)" "unprognostic (1.20e-7)" "unprognostic (2.67e-1)" "unprognostic (1.10e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-3)" 0.2 0.5 1.2 0.8 1.2 1.6 0.2 1.4 1.7 0.4 1.2 0.2 0.3 0.3 0.1 0.1 0.4 0.0 0.2 1.1 1.2 0.9 0.2 0.2 0.3 1.3 1.2 0.5 0.1 0.1 0.4 0.3 1.4 0.3 0.3 5.8 0.1 0.1 0.5 0.7 0.3 0.1 1.1 0.4 0.2 1.1 1.3 0.4 0.3 0.1 0.3 0.3 0.2 1.5 0.4 0.5 0.6 0.8 0.2 0.1 0.2 0.0 0.0 0.6 0.2 0.9 0.1 1.2 0.1 0.0 0.4 0.6 0.8 0.1 0.6 0.3 0.6 1.0 0.4 0.4 0.0 0.2 0.8 0.0 0.4 0.3 0.4 0.1 0.2 1.2 0.6 0.2 0.1 1.3 0.4 1.0 1.2 1.2 0.1 0.8 2.2 0.7 0.5 1.3 0.4 0.4 0.4 0.1 0.9 0.9 0.5 0.5 0.4 0.3 0.8 0.7 0.5 0.6 0.4 0.6 0.4 1.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.2 1.4 1.7 1.1 1.2 1.3 1.2 1.4 1.1 1.3 1.5 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 7.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.8 0.2 0.0 0.0 0.0 RSPH3 "dJ111C20.1, RSHL2, RSP3" ENSG00000130363 "Radial spoke head 3" 6 158972871-159000202 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 149.3;Respiratory ciliated cells: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039109 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "HPA039109: AB_10794423" "unprognostic (6.18e-3)" "unprognostic (3.62e-3)" "unprognostic (4.54e-2)" "unprognostic (6.20e-2)" "unprognostic (1.88e-1)" "unprognostic (9.18e-2)" "unprognostic (1.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (6.74e-3)" "unprognostic (6.98e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.19e-4)" "unprognostic (5.89e-2)" "unprognostic (1.67e-1)" "unprognostic (5.14e-2)" "unprognostic (1.79e-2)" 2.9 4.7 0.8 2.2 1.0 1.6 3.7 0.2 4.7 3.9 14.5 4.2 5.9 3.4 4.6 5.7 6.1 3.3 3.8 2.0 1.0 6.3 2.7 4.6 1.4 1.9 2.6 3.4 4.3 13.2 3.5 3.1 1.5 5.2 3.7 6.7 4.4 4.1 1.5 3.8 5.6 3.7 1.6 2.3 4.1 9.9 1.1 1.8 7.6 2.2 2.0 2.9 3.0 1.6 8.5 3.7 2.1 4.9 4.8 6.3 2.2 6.2 7.0 1.9 2.8 1.2 4.6 1.7 4.8 7.2 6.3 6.1 1.4 5.6 2.8 4.4 2.9 2.2 3.9 2.6 4.6 2.4 1.6 7.1 9.5 3.8 6.9 10.0 2.5 2.5 2.8 2.6 4.5 4.3 1.5 2.7 1.2 3.8 2.7 2.2 0.3 1.6 8.6 2.6 2.8 4.0 11.6 3.8 2.2 2.4 4.7 5.3 5.4 2.0 5.5 4.8 3.0 2.9 6.1 1.2 10.1 2.9 3.9 0.9 4.0 0.6 0.6 3.0 1.2 0.9 0.9 1.2 4.0 2.4 0.7 1.1 10.5 1.7 7.0 4.6 1.3 1.5 0.8 1.0 0.2 4.7 2.0 1.0 1.9 2.6 1.5 1.6 1.1 1.6 2.3 25.6 17.9 15.0 4.0 7.4 17.2 19.1 6.2 14.2 12.2 7.6 17.5 17.2 25.1 22.0 35.5 10.3 5.7 25.6 13.7 15.8 149.3 67.0 6.9 6.0 13.1 2.1 32.8 10.2 11.4 7.6 10.2 12.7 2.5 9.2 7.9 8.4 10.1 3.3 18.5 17.6 16.2 9.5 16.5 62.9 14.0 12.6 7.2 4.7 8.3 14.4 4.1 6.0 3.5 13.1 21.1 17.7 5.7 18.4 33.1 19.7 120.4 32.5 6.6 5.9 10.2 57.3 10.9 18.6 8.8 5.9 6.1 12.2 13.1 23.1 RTL3 "FLJ38865, Mar3, Mart3, SIRH9, ZCCHC5, ZHC5" ENSG00000179300 "Retrotransposon Gag like 3" Q8N8U3 X 78656068-78659328 "Predicted intracellular proteins" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+ SV40 Large T+ RasG12V: 1.1;fHDF/TERT166: 1.8;GAMG: 1.4;HBF TERT88: 2.4;hTEC/SVTERT24-B: 1.7;RH-30: 2.1;U-251 MG: 1.6" "Region enriched" "Detected in single" 9 "hippocampal formation: 2.8" "HPA051991, HPA053174, HPA075136" Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Golgi apparatus, Plasma membrane" "HPA051991: AB_2681683, HPA053174: AB_2682069, HPA075136: AB_2686737" "unprognostic (3.43e-1)" "unprognostic (1.06e-1)" "unprognostic (1.29e-1)" "unprognostic (6.74e-2)" "unprognostic (5.11e-2)" "unprognostic (8.64e-2)" "unprognostic (1.23e-1)" "unprognostic (1.69e-2)" "unprognostic (2.85e-1)" "unprognostic (4.00e-6)" "unprognostic (1.53e-2)" "unprognostic (3.64e-1)" "unprognostic (2.49e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.3 0.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.8 1.0 1.1 0.0 0.0 0.0 0.0 1.8 1.4 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.0 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.6 0.0 1.6 0.0 0.0 0.0 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RTL4 "FLJ46608, Mar4, Mart4, SIRH11, ZCCHC16" ENSG00000187823 "Retrotransposon Gag like 4" Q6ZR62 X 112454500-112457112 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "liver: 1.1" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "testis cancer: 1.4;thyroid cancer: 3.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA003272 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: Liver - Metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Cytosol" "HPA003272: AB_2257414" "unprognostic (9.86e-2)" "unprognostic (2.04e-4)" "unprognostic (6.35e-2)" "unprognostic (5.33e-3)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.8 1.1 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.1 0.2 0.3 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RTN4R NOGOR ENSG00000040608 "Reticulon 4 receptor" Q9BZR6 22 20241415-20283246 "Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.3;liver: 12.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 12.1;Excitatory neurons: 14.1;Muller glia cells: 11.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 8.0;basal ganglia: 20.0;cerebellum: 20.9;cerebral cortex: 24.3;hippocampal formation: 12.7" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 10.8" "Lineage enriched" "Detected in many" 9 "T-cells: 10.8" "Cell line enhanced" "Detected in many" "NB-4: 38.2;REH: 53.9;SCLC-21H: 31.3;SK-MEL-30: 25.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB012443 Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 1900000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 6: Brain - Smell perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Focal adhesion sites" "Actin filaments" "CAB012443: " "unprognostic (1.28e-1)" "unprognostic (1.28e-2)" "unprognostic (8.29e-2)" "unprognostic (6.58e-2)" "unprognostic (3.49e-1)" "prognostic unfavorable (7.73e-4)" "unprognostic (2.19e-1)" "unprognostic (1.56e-1)" "unprognostic (3.44e-1)" "unprognostic (8.90e-3)" "unprognostic (1.21e-2)" "unprognostic (9.89e-2)" "unprognostic (1.80e-2)" "unprognostic (1.34e-2)" "unprognostic (1.30e-1)" "unprognostic (5.02e-2)" "unprognostic (3.07e-1)" 1.6 2.6 8.0 0.5 20.0 0.6 1.0 20.9 24.3 3.6 0.0 1.6 2.2 5.1 0.0 3.5 1.9 0.1 2.7 12.7 0.0 2.1 12.8 2.2 0.4 0.5 0.0 2.4 3.7 0.4 4.9 0.4 0.3 1.5 0.1 0.6 2.0 0.4 0.6 7.9 2.1 0.2 0.0 8.5 1.8 1.9 0.4 0.8 3.5 0.2 0.2 0.5 2.8 1.8 7.9 3.8 2.3 5.5 0.0 0.0 1.2 0.8 0.0 0.6 0.3 6.0 2.2 0.4 2.5 0.1 3.7 12.8 1.4 3.2 0.0 0.2 13.4 0.1 3.2 0.9 1.3 0.3 0.4 0.0 4.1 0.0 0.3 0.0 0.0 3.7 0.4 0.3 0.0 11.0 4.1 38.2 8.7 2.3 6.7 53.9 0.0 0.4 0.5 3.3 31.3 5.0 3.7 2.7 25.9 0.5 3.1 1.1 0.0 0.5 14.2 0.1 0.2 0.1 1.0 0.9 0.4 7.8 0.1 0.0 0.0 0.0 4.6 0.0 10.8 0.0 4.0 4.6 0.2 0.1 2.4 5.1 0.0 0.8 0.0 1.2 3.0 1.7 8.0 20.0 20.9 24.3 12.7 0.0 0.5 0.0 0.3 0.0 0.4 1.8 1.4 3.2 0.0 7.5 0.2 5.1 4.0 1.6 1.8 12.1 2.9 2.4 2.2 0.0 0.6 0.0 4.2 0.2 1.9 3.0 0.0 2.9 2.0 1.2 4.8 2.0 0.0 0.4 14.1 4.3 7.6 1.6 0.0 1.6 0.0 0.4 1.1 3.0 1.3 6.7 2.6 2.6 0.0 0.0 0.7 0.5 0.3 1.7 1.8 2.8 0.7 11.3 2.1 2.5 2.4 3.4 0.4 0.0 0.1 3.9 0.6 0.0 0.0 4.9 0.0 0.2 1.0 0.1 1.2 2.0 5.5 0.0 2.5 0.1 2.1 3.5 RTN4RL1 "DKFZp547J144, NgR3, NGRH2" ENSG00000185924 "Reticulon 4 receptor like 1" Q86UN2 17 1934677-2025334 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 20.6;Cone photoreceptor cells: 37.5;Excitatory neurons: 43.5;Horizontal cells: 33.7;Inhibitory neurons: 18.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "hippocampal formation: 12.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 10.9;HaCaT: 10.8;hTCEpi: 10.1;T-47d: 13.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044428 Uncertain Approved "Nucleoplasm,Plasma membrane,Actin filaments,Midbody" "Intracellular and membrane" Yes NA 35000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Actin filaments" "Nucleoplasm, Plasma membrane, Midbody" "HPA044428: AB_10963229" "unprognostic (5.23e-1)" "unprognostic (3.52e-2)" "unprognostic (2.06e-1)" "unprognostic (2.12e-1)" "unprognostic (2.93e-2)" "unprognostic (7.25e-2)" "unprognostic (2.61e-3)" "unprognostic (1.17e-1)" "unprognostic (8.97e-3)" "unprognostic (6.21e-2)" "unprognostic (2.55e-3)" "unprognostic (6.32e-3)" "prognostic unfavorable (7.69e-4)" "unprognostic (3.86e-2)" "unprognostic (1.05e-1)" "unprognostic (7.01e-2)" "unprognostic (3.15e-2)" 4.0 3.1 4.6 0.3 4.0 0.0 6.4 0.0 9.2 2.1 0.0 0.4 0.1 0.8 0.2 1.3 1.5 0.6 2.3 12.3 0.3 1.6 2.6 1.6 0.1 0.0 0.5 0.9 1.8 1.3 5.9 0.3 0.0 3.4 0.1 8.5 4.4 2.0 1.8 9.6 0.5 0.3 0.0 1.1 0.7 0.8 1.9 0.2 1.4 0.4 0.1 1.5 2.2 0.0 1.4 1.6 1.8 2.5 2.0 0.3 0.0 0.1 1.1 0.3 0.0 0.0 0.0 0.0 0.1 10.9 0.2 10.8 4.6 0.1 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.9 10.1 0.0 3.6 0.0 0.0 2.5 0.1 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.3 0.8 0.3 1.2 0.0 0.0 2.2 0.0 0.3 0.8 1.7 0.2 13.3 0.1 0.0 0.0 0.2 0.5 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.0 0.0 9.2 12.3 0.3 0.0 0.5 0.0 0.0 1.9 0.0 1.0 0.0 2.2 1.6 0.1 2.7 0.2 0.0 1.8 20.6 5.4 4.3 3.0 1.5 1.3 3.7 37.5 0.0 0.1 0.0 0.0 0.6 0.3 0.0 0.0 0.7 0.0 0.0 43.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 6.1 3.3 1.8 33.7 18.6 0.0 0.0 0.3 0.4 1.1 0.0 0.1 3.6 7.5 0.0 1.8 0.0 8.5 1.7 0.1 0.0 0.0 0.1 0.9 0.0 0.1 1.5 10.0 0.0 0.0 0.6 0.0 0.2 0.5 2.8 0.0 0.2 0.0 0.0 0.3 RYR2 "ARVC2, ARVD2, VTSIP" ENSG00000198626 "Ryanodine receptor 2" Q92736 1 237042184-237833988 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Calmodulin-binding, Developmental protein, Ion channel, Ligand-gated ion channel, Receptor" "Cardiomyopathy, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "heart muscle: 132.0" "Group enriched" "Detected in many" 10 "Cardiomyocytes: 2180.6;Excitatory neurons: 1320.5;Inhibitory neurons: 790.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.7;HEK 293: 8.5;K-562: 2.3;NB-4: 2.7;NTERA-2: 3.1;U-937: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020028 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane, Cytosol" "HPA020028: AB_1856528" "unprognostic (5.23e-3)" "unprognostic (2.15e-2)" "unprognostic (5.02e-4)" "unprognostic (6.26e-2)" "unprognostic (8.74e-2)" "unprognostic (2.99e-3)" "unprognostic (5.28e-2)" "unprognostic (1.45e-3)" "unprognostic (2.69e-2)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (0.00e+0)" "unprognostic (2.36e-2)" "unprognostic (1.42e-1)" "unprognostic (3.13e-2)" "unprognostic (1.06e-2)" 0.7 0.7 9.1 0.8 15.9 0.0 0.6 8.7 24.0 1.5 0.0 2.0 0.2 0.7 0.4 2.9 0.7 1.9 132.0 10.5 0.0 0.1 0.1 1.8 0.1 0.0 0.0 2.9 8.4 0.0 1.8 1.2 0.0 2.9 0.5 6.5 0.5 1.7 0.1 0.3 0.5 0.7 0.0 1.3 1.5 1.1 0.0 0.1 4.4 0.3 0.0 1.2 0.4 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.0 0.9 0.3 0.0 0.0 7.7 8.5 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 2.3 0.4 0.0 0.0 0.0 2.7 3.1 0.6 0.3 0.0 0.1 0.2 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 9.1 15.9 8.7 24.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 13.2 0.2 0.0 0.5 17.0 0.0 0.4 0.0 0.0 0.0 74.2 0.3 0.1 2180.6 0.0 1.3 1.8 10.4 0.1 0.1 0.0 0.0 0.0 21.1 0.2 3.4 10.6 3.5 0.0 1320.5 2.9 0.1 53.6 0.0 0.5 0.0 0.5 1.1 0.0 0.1 1.7 790.6 0.0 0.0 0.0 0.2 15.3 1.2 1.3 8.8 48.7 0.0 1.3 0.0 29.7 140.6 0.4 0.0 0.0 0.1 0.0 1.0 0.2 0.7 5.3 0.0 0.5 21.6 5.8 2.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 S100A13 ENSG00000189171 "S100 calcium binding protein A13" Q99584 1 153618787-153631360 "Predicted intracellular proteins, Predicted secreted proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Theca cells: 3084.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 28.3" "Group enriched" "Detected in all" 5 "dendritic cells: 11.9;NK-cells: 28.3" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 811.3;SuSa: 896.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019592, CAB025494" Approved Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 36000 "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "Nucleoplasm, Nucleoli" "CAB025494: , HPA019592: AB_10601499" "unprognostic (1.50e-2)" "unprognostic (9.09e-2)" "unprognostic (2.08e-2)" "unprognostic (1.45e-1)" "unprognostic (7.77e-2)" "unprognostic (9.72e-3)" "unprognostic (1.75e-3)" "unprognostic (9.93e-2)" "unprognostic (6.48e-2)" "unprognostic (1.67e-1)" "unprognostic (1.21e-2)" "unprognostic (4.83e-3)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.43e-2)" "unprognostic (8.10e-2)" "unprognostic (1.82e-3)" "unprognostic (1.72e-2)" 275.3 137.3 237.4 47.7 247.3 4.4 222.4 241.0 347.5 133.7 214.6 198.9 30.6 111.8 72.1 91.7 129.8 103.9 310.1 233.1 240.8 262.2 66.2 138.0 48.8 252.9 245.5 138.2 75.7 317.4 73.9 70.1 249.4 100.9 59.8 25.8 156.1 64.6 250.6 114.0 116.5 68.9 245.8 111.7 94.4 41.2 251.6 21.2 318.7 220.6 49.6 121.2 122.7 258.6 188.7 153.7 174.5 111.4 150.7 437.5 62.7 254.7 400.0 150.6 172.2 150.4 203.7 4.9 471.6 435.5 22.3 174.7 73.5 158.7 132.7 0.8 68.1 12.0 178.0 129.6 99.8 5.9 39.2 355.3 59.4 135.3 145.0 441.9 346.5 1.3 61.4 0.3 475.2 663.4 0.4 3.4 141.0 161.1 460.2 30.0 180.4 1.4 811.3 141.9 53.4 2.0 544.7 277.2 576.7 896.9 226.4 6.8 495.0 103.3 57.9 139.5 312.0 2.0 5.3 9.3 185.5 3.2 62.1 4.1 2.0 0.2 0.4 0.9 0.9 4.1 0.4 0.3 7.0 2.0 0.6 0.5 0.3 28.3 1.4 11.9 1.4 1.1 237.4 247.3 241.0 347.5 233.1 240.8 252.9 245.5 249.4 245.8 251.6 258.6 331.0 28.9 106.1 29.7 9.3 110.5 177.4 105.0 103.0 2.1 311.2 345.6 141.9 164.5 104.0 465.3 0.0 132.4 15.3 148.7 248.4 323.3 8.4 399.3 449.1 251.9 124.7 17.3 1.2 323.6 202.1 450.0 58.6 573.8 23.5 185.5 372.3 51.8 162.3 0.0 0.5 167.5 61.1 31.7 107.7 36.3 771.7 37.1 238.3 13.1 14.8 308.1 1.0 0.0 8.8 488.4 164.7 314.1 6.3 240.0 128.7 521.7 77.1 6.9 0.0 234.2 132.5 12.8 23.4 80.3 75.7 74.7 20.5 3084.7 100.6 244.3 S100A14 "BCMP84, S100A15" ENSG00000189334 "S100 calcium binding protein A14" Q9HCY8 1 153614255-153616986 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 3719.5;vagina: 1174.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 2340.8;Paneth cells: 1098.9;Proximal enterocytes: 1549.1;Squamous epithelial cells: 3205.8;Suprabasal keratinocytes: 3612.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 798.6;HaCaT: 1072.9;HBEC3-KT: 1527.6;hTCEpi: 2232.0;OE19: 1675.1;SK-BR-3: 1579.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA027613 Enhanced Approved "Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA 260000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nuclear bodies, Plasma membrane, Cell Junctions, Cytosol" "HPA027613: AB_10602298" "unprognostic (1.73e-1)" "unprognostic (1.85e-1)" "unprognostic (1.48e-1)" "unprognostic (3.94e-2)" "unprognostic (1.75e-2)" "unprognostic (6.27e-2)" "unprognostic (2.30e-2)" "unprognostic (9.48e-2)" "unprognostic (2.50e-1)" "unprognostic (2.16e-1)" "unprognostic (2.75e-3)" "unprognostic (2.89e-1)" "unprognostic (3.16e-3)" "unprognostic (8.41e-2)" "unprognostic (1.80e-1)" "unprognostic (4.81e-2)" "unprognostic (9.53e-2)" 2.2 0.8 1.5 24.9 1.6 0.2 78.3 1.5 2.0 530.8 1.3 241.0 265.4 5.4 14.7 3719.5 20.4 18.5 4.2 1.5 1.5 70.1 16.3 82.7 0.6 1.5 1.5 1.4 17.7 125.2 5.1 1.1 1.5 19.6 240.0 0.0 550.3 39.0 2.2 608.0 209.0 13.1 1.4 1.3 119.2 0.7 1.7 149.0 98.6 0.0 449.7 32.9 1174.2 1.5 798.6 0.2 0.1 0.2 0.2 0.3 7.4 0.2 0.1 0.2 0.1 97.6 140.1 0.6 2.3 0.2 0.5 1072.9 0.0 1527.6 0.1 0.5 0.3 0.1 10.8 7.3 0.0 0.0 0.9 0.6 2232.0 0.5 20.7 0.3 0.3 0.1 0.6 1.1 0.2 140.0 0.7 1.1 0.4 1675.1 1.9 0.6 0.6 2.8 8.1 51.2 0.7 0.7 2.2 1579.1 2.1 36.5 3.9 1.7 0.0 0.7 0.8 1.1 2.0 0.4 0.8 0.9 0.6 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.6 1.5 2.0 1.5 1.5 1.5 1.5 1.5 1.4 1.7 1.5 2.7 60.9 162.6 2.3 4.2 2340.8 448.6 770.5 657.9 0.0 256.2 178.3 5.3 270.2 387.7 35.0 0.0 2.7 2.2 1058.2 49.0 197.5 0.0 37.3 6.4 21.5 153.4 0.0 0.0 65.8 1.5 22.8 85.6 80.3 28.0 0.2 1.1 9.5 0.3 0.0 0.0 660.1 126.1 0.3 213.7 0.0 0.0 3.0 241.9 0.0 2.0 0.0 0.0 0.0 0.1 343.0 1098.9 0.0 7.5 619.3 1549.1 4.9 56.2 0.0 0.0 1.3 27.1 0.0 0.0 3205.8 3612.0 0.3 8.7 13.6 580.9 824.9 S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 995.4;Pancreatic endocrine cells: 1307.3;Prostatic glandular cells: 1141.1;Squamous epithelial cells: 1028.7;Suprabasal keratinocytes: 908.8;Theca cells: 1528.4;Urothelial cells: 1522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1369.9;SK-BR-3: 1618.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" 166.8 79.1 81.3 61.9 79.8 0.8 159.7 78.6 98.0 333.0 70.8 139.7 121.5 78.4 19.8 2477.7 68.2 81.6 122.3 79.8 80.1 219.0 209.9 161.3 28.4 104.2 80.9 83.4 41.0 76.6 42.0 71.8 84.9 77.8 105.0 7.0 438.1 38.1 51.7 474.9 109.8 79.0 84.8 118.5 100.4 60.3 103.4 25.0 72.4 52.1 205.0 163.2 713.3 84.6 670.4 318.1 16.0 36.7 102.5 386.8 42.8 367.9 341.4 302.7 265.2 315.4 366.1 0.3 577.5 553.0 69.0 479.6 1.1 839.2 175.3 1.9 0.6 0.4 260.5 90.8 117.5 0.2 0.9 182.7 787.6 731.6 567.9 390.9 1369.9 0.0 8.5 0.8 677.3 918.7 0.9 1.4 69.0 1171.0 887.9 0.9 187.4 1.8 1150.3 236.1 0.8 1.9 267.6 1618.0 55.7 140.5 504.7 3.5 743.9 178.2 289.5 171.5 848.6 0.5 3.5 2.4 525.0 0.9 122.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 81.3 79.8 78.6 98.0 79.8 80.1 104.2 80.9 84.9 84.8 103.4 84.6 275.6 38.5 25.5 10.4 6.8 633.9 995.4 531.6 157.6 0.5 225.4 191.3 33.0 124.4 290.6 108.5 2.1 20.3 4.4 500.7 72.4 610.9 4.9 50.9 172.5 293.5 139.0 16.0 0.0 193.9 8.7 112.2 96.8 128.5 19.1 154.1 365.9 132.7 5.0 0.0 0.1 286.4 164.8 15.7 95.4 17.4 67.1 7.4 112.1 5.6 7.2 72.5 0.0 7.5 0.7 1307.3 610.0 61.3 5.6 1141.1 353.3 169.7 48.6 2.1 6.6 70.9 91.2 8.0 1.3 1028.7 908.8 8.2 12.9 1528.4 320.2 1522.5 S100A2 "CAN19, S100L" ENSG00000196754 "S100 calcium binding protein A2" P29034 1 153561108-153567890 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 3574.5;kidney: 1380.0;urinary bladder: 1097.4" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 11464.4;Basal prostatic cells: 4796.7;Basal respiratory cells: 10600.9;Basal squamous epithelial cells: 4741.9;Club cells: 3331.1;Prostatic glandular cells: 9446.4;Squamous epithelial cells: 9013.7;Suprabasal keratinocytes: 3626.5;Urothelial cells: 5382.7" "Cancer enhanced" "Detected in all" "cervical cancer: 848.8;head and neck cancer: 1229.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 10.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 10.1" "Group enriched" "Detected in many" 5 "HBEC3-KT: 21286.9;RT4: 8382.8" "Not detected" "Not detected" "Not detected" "Not detected" "CAB002600, CAB047340, HPA062451" Enhanced Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA 27000 "Cluster 10: Basophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "CAB002600: , CAB047340: , HPA062451: AB_2684767" "unprognostic (8.47e-3)" "unprognostic (5.54e-2)" "unprognostic (1.57e-2)" "unprognostic (1.42e-3)" "unprognostic (1.98e-1)" "unprognostic (3.20e-1)" "unprognostic (4.21e-4)" "unprognostic (9.00e-2)" "unprognostic (1.64e-1)" "unprognostic (1.23e-2)" "prognostic unfavorable (2.04e-4)" "unprognostic (3.52e-2)" "unprognostic (8.91e-2)" "unprognostic (1.35e-1)" "unprognostic (2.70e-1)" "unprognostic (1.39e-1)" "unprognostic (2.68e-1)" 4.0 2.1 2.5 4.1 2.7 1.0 17.3 2.4 3.6 279.9 2.0 3.1 0.8 2.5 16.1 3574.5 5.6 1.8 3.9 2.3 3.2 1380.0 1.7 12.0 0.5 4.1 3.0 1.9 2.1 0.1 5.4 0.8 3.0 48.1 1.6 0.4 377.1 16.9 3.3 429.6 1.6 1.9 3.0 1.5 3.6 2.8 3.4 6.3 11.9 1.4 416.1 1097.4 747.3 3.5 827.0 9.3 1.1 0.9 10.8 4.2 1.2 10.4 11.5 9.0 7.8 2.1 26.8 1.2 418.3 17.8 18.3 2001.4 1.3 21286.9 9.9 5.4 3.7 3.8 56.2 5.0 4.5 0.7 1.9 8.8 2777.8 24.1 3135.5 21.7 13.2 0.0 0.8 1.5 47.7 3.4 0.2 0.2 2.2 22.3 155.4 1.3 497.9 2.1 502.4 8382.8 16.5 0.5 34.9 5.8 9.0 5.9 3.2 5.7 6.0 12.5 692.6 92.4 280.6 1.9 2.4 4.7 26.5 1.8 24.2 10.1 0.4 0.0 2.3 0.0 1.4 0.4 1.6 1.3 0.3 0.0 0.4 0.3 4.3 0.0 0.5 2.2 1.6 0.7 2.5 2.7 2.4 3.6 2.3 3.2 4.1 3.0 3.0 3.0 3.4 3.5 1.4 9.6 17.3 2.6 1.0 11464.4 4796.7 10600.9 4741.9 0.0 22.2 35.4 2.9 1.5 3331.1 218.8 0.0 0.7 0.8 3.2 1226.7 24.8 4.5 16.3 2.5 108.2 1.8 3.0 0.1 27.6 1.0 130.8 1.5 24.5 17.1 1.2 0.4 0.1 1.8 0.0 0.0 1.6 789.4 0.8 676.4 8.1 0.6 18.0 759.5 0.0 5.3 1.1 0.0 2.0 0.1 668.7 2.5 0.7 25.9 9446.4 0.8 11.8 560.8 0.1 0.0 5.5 207.0 0.6 3.0 9013.7 3626.5 0.3 37.8 8.9 2.0 5382.7 S100A3 S100E ENSG00000188015 "S100 calcium binding protein A3" P33764 1 153547329-153549258 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 94.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 15.4;Ductal cells: 21.7;Endometrial stromal cells: 18.4;Exocrine glandular cells: 24.0;Pancreatic endocrine cells: 24.2;Skeletal myocytes: 24.7" "Cancer enhanced" "Detected in all" "urothelial cancer: 26.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 9 "intermediate monocyte: 3.1;non-classical monocyte: 6.2;plasmacytoid DC: 7.4" "Group enriched" "Detected in many" 11 "dendritic cells: 7.4;monocytes: 6.2" "Cell line enhanced" "Detected in many" "A549: 87.0;HBEC3-KT: 45.7;HeLa: 51.4;U-2197: 47.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 15.8" "HPA042674, HPA056140" Enhanced Enhanced "Golgi apparatus,Plasma membrane,Cytosol" NA NA 240000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 31: Skin - Epidermis development" "Cluster 20: HeLa - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Golgi apparatus, Plasma membrane" "HPA042674: AB_10796581, HPA056140: AB_2683050" "unprognostic (3.90e-2)" "unprognostic (1.60e-1)" "unprognostic (3.59e-2)" "unprognostic (1.21e-2)" "unprognostic (4.53e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-1)" "unprognostic (2.36e-1)" "unprognostic (2.46e-1)" "unprognostic (2.08e-1)" "unprognostic (5.34e-3)" "unprognostic (3.97e-3)" "prognostic unfavorable (1.61e-6)" "unprognostic (8.13e-2)" "unprognostic (3.46e-1)" "unprognostic (6.21e-2)" "unprognostic (8.10e-2)" 7.6 1.1 0.9 3.6 1.1 1.8 4.2 0.8 1.3 6.9 0.6 2.8 0.5 3.9 0.2 17.2 3.3 1.7 2.6 0.8 1.4 13.8 0.2 16.6 1.8 1.4 1.6 1.1 0.8 0.1 0.7 2.2 1.2 3.0 1.1 0.0 4.2 1.7 1.0 94.6 1.9 2.1 1.1 0.8 1.4 0.5 2.8 0.4 1.5 1.9 5.1 6.9 9.6 1.4 7.3 87.0 0.1 0.1 8.1 5.2 0.0 6.1 31.4 7.9 12.8 2.6 2.8 0.1 19.0 16.1 10.7 22.2 0.1 45.7 3.7 0.3 0.0 0.3 51.4 15.3 2.2 0.0 0.3 4.1 24.9 17.9 19.9 4.5 1.7 0.0 0.0 0.0 39.8 0.5 0.0 0.0 0.6 0.2 11.5 0.0 5.9 4.7 26.0 18.3 1.2 0.0 5.4 6.1 2.0 24.7 0.2 0.6 8.6 2.9 4.8 47.4 6.3 1.4 1.6 0.2 38.2 0.7 19.1 0.0 0.1 0.0 0.0 3.1 0.2 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 6.2 7.4 0.1 0.4 0.9 1.1 0.8 1.3 0.8 1.4 1.4 1.6 1.2 1.1 2.8 1.4 2.0 3.2 0.5 0.7 0.0 10.3 2.3 15.4 4.0 0.0 0.3 0.4 0.3 1.5 5.9 0.0 0.0 0.3 0.0 0.0 1.9 21.7 0.0 2.3 18.4 7.4 0.0 1.3 0.0 24.0 4.4 8.4 0.0 1.3 0.0 0.0 2.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 11.1 0.1 4.1 0.4 1.8 0.0 3.6 0.0 0.0 0.0 0.0 24.2 0.0 0.4 0.0 1.5 0.0 0.3 1.1 0.0 0.0 24.7 9.6 0.1 0.0 5.6 6.5 1.5 0.5 1.1 0.0 2.0 S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 37545.1;Urothelial cells: 17431.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 17071.6;RPTEC TERT1: 20988.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 7000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: AB_1079859" "unprognostic (8.80e-3)" "unprognostic (6.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (1.66e-1)" "unprognostic (3.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "prognostic favorable (7.56e-4)" 1873.9 666.6 435.5 1129.7 452.5 2003.6 1499.2 456.2 549.9 2306.1 425.9 2872.2 1504.1 1058.4 404.8 1300.4 879.9 1485.5 1046.0 425.8 593.7 2326.6 91.9 2216.9 365.1 520.2 488.9 556.8 204.2 68.4 311.2 709.2 489.1 827.7 2252.2 36.6 1123.5 1169.3 478.1 858.6 1367.0 965.1 488.8 519.1 1586.3 170.1 573.3 191.6 970.0 1010.8 504.8 3867.5 1276.0 530.4 3666.6 4412.8 4.3 330.6 7597.2 10482.0 9.3 4560.1 13403.9 2582.7 3352.7 273.3 8022.5 4.5 1319.7 7774.8 2078.7 1589.3 80.7 7340.5 1322.0 1340.0 1.6 731.2 2579.1 255.8 2730.2 28.1 458.7 4550.0 6406.8 2638.7 4734.2 3259.1 6078.3 0.7 3.2 12.3 7052.7 589.4 11.4 292.3 9.6 17071.6 7563.4 5.5 463.0 1250.1 20988.4 3918.8 1019.8 142.6 6251.9 6380.9 4628.4 3.7 835.3 1095.9 7473.3 2228.2 489.8 4463.8 7452.6 8.8 11.9 15.5 8619.0 728.4 4773.0 5517.3 6053.2 2413.8 1806.1 3258.0 1983.1 937.8 1664.9 1773.1 4240.8 583.7 1037.2 1378.3 9637.7 297.4 3066.5 2145.0 2217.6 8320.4 435.5 452.5 456.2 549.9 425.8 593.7 520.2 488.9 489.1 488.8 573.3 530.4 1177.8 4708.3 2663.1 17.6 343.0 1488.3 6868.7 7856.4 2416.5 4.9 1494.4 1445.2 326.6 1474.1 7013.9 8165.9 0.0 1368.2 999.9 8832.0 7446.5 6206.3 21.3 1148.6 3473.2 1801.5 2035.6 637.5 14.7 9903.1 2440.0 4102.1 2276.3 814.3 1817.4 126.3 946.3 21.6 2430.3 58.9 7.1 6823.9 5706.7 2853.5 7378.0 115.0 3013.4 3110.9 3070.0 30.0 6073.8 168.0 926.9 7.5 23.0 37545.1 9094.3 1143.8 346.6 9900.7 8570.5 224.3 4962.3 8.7 131.5 3234.0 2978.8 28.7 13.2 1718.7 997.6 1573.4 1283.0 5881.5 3218.9 17431.0 S100A9 "60B8AG, CAGB, CFAG, CGLB, LIAG, MAC387, MIF, MRP14, NIF, P14" ENSG00000163220 "S100 calcium binding protein A9" P06702 1 153357854-153361023 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Apoptosis, Autophagy, Chemotaxis, Immunity, Inflammatory response, Innate immunity" "Antimicrobial, Antioxidant" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 32194.3;esophagus: 30581.7;vagina: 14027.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5771.3;Kupffer cells: 7537.0;Macrophages: 3678.1;monocytes: 11103.1;Squamous epithelial cells: 3263.1" "Cancer enhanced" "Detected in all" "cervical cancer: 5468.0;head and neck cancer: 6692.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 6 "classical monocyte: 24579.6;neutrophil: 33654.0" "Group enriched" "Detected in all" 6 "granulocytes: 33654.0;monocytes: 24579.6" "Cell line enriched" "Detected in many" 6 "SK-BR-3: 2398.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA004193, CAB009441" Enhanced Supported "Nucleoplasm,Cell Junctions,Cytosol" "Secreted to blood" NA NA 10600000 1200000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Cell Junctions, Cytosol" "CAB009441: AB_2184420, HPA004193: AB_1856537" "unprognostic (1.72e-1)" "unprognostic (3.33e-2)" "unprognostic (2.40e-1)" "unprognostic (3.94e-3)" "unprognostic (1.36e-2)" "unprognostic (5.45e-3)" "prognostic unfavorable (1.13e-6)" "unprognostic (1.10e-2)" "unprognostic (4.31e-1)" "unprognostic (3.06e-1)" "unprognostic (1.35e-2)" "unprognostic (5.59e-2)" "prognostic unfavorable (8.10e-4)" "unprognostic (1.48e-1)" "unprognostic (7.52e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-2)" 706.4 126.1 19.7 1505.7 24.3 32194.3 189.8 21.4 67.8 7849.1 28.5 123.9 24.1 50.0 2.0 30581.7 486.1 147.4 208.5 19.4 21.9 171.7 284.0 1629.4 69.3 28.7 24.2 51.5 73.9 11.5 65.4 370.1 30.0 91.3 20.2 3.6 5790.0 9.6 92.2 416.7 120.6 480.7 22.0 5381.4 187.6 16.7 26.5 197.7 90.4 150.4 4378.8 955.1 14027.7 25.4 24.6 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 1.5 0.0 9.2 372.2 0.0 0.4 23.0 0.0 157.3 0.0 0.4 0.0 6.2 0.0 0.1 0.0 7.8 0.0 0.0 130.2 0.0 8.4 0.0 0.0 0.1 7.6 3.5 0.0 31.4 0.8 3.3 0.1 3.1 0.2 0.8 5.1 82.2 0.3 100.4 1.3 0.6 4.0 2398.2 1.7 1.2 38.1 312.3 6.8 0.0 3.3 0.4 0.4 0.7 1.6 3.3 0.5 71.7 0.0 373.8 24579.6 2626.3 30.5 1754.8 52.6 29.7 25.3 17.2 4664.8 24.8 17.7 15.4 33654.0 18.8 860.2 153.3 29.2 24461.7 19.7 24.3 21.4 67.8 19.4 21.9 28.7 24.2 30.0 22.0 26.5 25.4 1.8 230.8 392.4 0.0 92.1 20.0 123.1 5771.3 28.5 0.0 55.6 6.7 8.0 57.2 1685.0 36.8 0.0 126.1 115.1 7.7 5.9 102.6 1.7 1.2 1.9 26.9 0.0 92.8 0.0 39.4 52.9 50.9 3.6 9.4 164.0 0.2 70.6 54.5 1926.0 0.0 0.0 3.7 309.3 7537.0 13.4 4.0 5.9 3678.1 0.0 0.0 11103.1 0.0 483.0 0.0 0.0 15.3 1.4 0.0 13.1 55.6 0.8 25.2 262.8 0.3 0.0 13.3 60.4 0.3 1.2 3263.1 33.2 1236.0 79.9 0.0 12.5 551.3 SAMD4A "DKFZP434H0350, hSmaug1, KIAA1053, SAMD4, Smaug, SMG, SMGA" ENSG00000020577 "Sterile alpha motif domain containing 4A" Q9UPU9 14 54566117-54793315 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 94.3;testis: 107.9" "Group enriched" "Detected in many" 4 "Early spermatids: 1176.0;Late spermatids: 2275.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 1.2;non-classical monocyte: 1.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043061, HPA065309" Approved Approved "Cell Junctions,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" Cytosol "HPA043061: AB_2678299, HPA065309: AB_2685462" "unprognostic (1.46e-1)" "unprognostic (8.10e-3)" "unprognostic (9.66e-3)" "unprognostic (1.18e-4)" "unprognostic (2.79e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-1)" "unprognostic (1.17e-1)" "unprognostic (1.13e-1)" "unprognostic (1.75e-1)" "unprognostic (1.98e-1)" "unprognostic (7.74e-2)" "unprognostic (1.09e-2)" "unprognostic (2.83e-2)" "unprognostic (8.27e-2)" "unprognostic (5.41e-2)" "unprognostic (1.51e-1)" 16.6 4.2 27.4 8.9 33.1 0.4 13.1 42.3 24.9 13.0 14.1 37.6 3.2 26.1 4.0 6.7 12.0 6.0 47.8 22.6 40.3 12.4 16.6 21.2 4.6 79.0 46.2 4.5 6.2 3.8 6.1 9.2 69.4 14.5 4.8 2.6 7.0 9.4 94.3 8.9 10.4 17.1 64.1 7.1 10.9 107.9 41.8 1.1 7.0 39.3 3.1 17.7 12.8 60.8 32.9 2.9 6.7 3.4 14.0 21.3 11.7 27.4 41.4 22.3 22.0 36.8 7.8 1.8 14.0 41.7 8.8 22.6 6.6 14.2 32.8 16.5 2.8 0.0 4.0 7.7 7.7 0.0 0.2 12.6 5.3 15.9 23.4 6.5 17.1 0.0 2.6 0.0 11.0 2.4 0.4 0.1 3.1 0.2 7.5 0.9 13.5 0.1 11.0 10.8 1.0 10.7 4.0 5.2 15.9 13.8 21.0 0.3 37.1 26.6 41.1 6.6 8.7 0.1 0.1 0.0 7.5 0.6 8.4 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 27.4 33.1 42.3 24.9 22.6 40.3 79.0 46.2 69.4 64.1 41.8 60.8 16.0 25.6 1.5 170.1 7.4 39.6 47.0 12.0 1.2 2.4 6.2 6.1 278.5 14.3 9.9 18.4 8.4 10.5 1.6 4.4 3.9 9.9 1176.0 13.7 45.3 30.9 6.0 5.7 64.6 8.0 1.8 47.3 1.5 29.3 22.8 0.8 10.8 62.6 11.6 10.1 173.7 1.5 6.1 15.3 28.9 2275.7 14.6 13.0 24.9 72.1 12.8 1.5 1.0 380.5 140.7 19.8 5.5 23.7 0.3 55.1 5.6 22.9 4.0 5.4 13.1 79.7 37.1 17.1 7.6 0.4 24.3 1.9 5.7 0.3 1.7 44.5 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SAMSN1 "HACS1, NASH1, SASH2, SH3D6B, SLy2" ENSG00000155307 "SAM domain, SH3 domain and nuclear localization signals 1" Q9NSI8 21 14485228-14658821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9;lymphoid tissue: 80.1" "Cell type enhanced" "Detected in many" "granulocytes: 1174.1;Langerhans cells: 317.9;Macrophages: 414.6;monocytes: 829.9;T-cells: 332.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 314.2" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HEL: 273.7;K-562: 331.6;Karpas-707: 137.3" "Region enriched" "Detected in many" 6 "olfactory bulb: 20.7" "Low region specificity" "Detected in all" "HPA010645, HPA017055, HPA046639" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Nucleoplasm "HPA010645: AB_1856559, HPA017055: AB_1856560, HPA046639: AB_2679732" "unprognostic (7.62e-3)" "unprognostic (1.46e-2)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (2.44e-1)" "unprognostic (3.91e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.13e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (4.52e-6)" "unprognostic (9.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.17e-1)" "unprognostic (1.68e-2)" 32.3 6.7 2.4 80.1 2.8 192.9 4.7 3.3 4.9 5.7 4.2 11.0 7.0 3.4 1.9 5.3 6.3 22.7 4.5 2.5 3.5 4.2 17.5 22.9 35.4 6.2 4.5 1.3 3.1 2.0 2.1 15.5 6.1 3.9 15.3 12.7 2.8 2.2 0.7 1.5 15.1 10.8 5.1 32.0 9.3 1.2 4.6 22.4 2.2 1.2 41.0 39.7 2.5 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.1 0.0 0.0 0.0 0.0 1.8 0.0 14.0 0.0 273.7 0.0 0.0 0.0 32.5 12.7 0.1 0.0 0.0 37.9 10.2 3.6 4.8 331.6 137.3 0.0 0.0 15.9 39.5 0.1 0.0 0.2 26.8 0.3 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 35.0 0.0 0.0 0.0 0.0 58.2 0.5 0.3 1.4 20.7 0.0 314.2 38.7 234.6 22.1 52.3 15.4 27.3 42.8 33.3 25.0 15.4 26.8 19.1 49.4 18.0 83.0 0.9 60.3 33.6 2.4 2.8 3.3 4.9 2.5 3.5 6.2 4.5 6.1 5.1 4.6 8.9 4.8 22.4 54.9 0.7 127.5 15.6 1.1 0.0 1.8 64.9 2.7 3.0 1.2 1.5 11.2 36.8 0.0 0.5 147.9 0.7 0.0 0.6 0.0 0.8 0.2 8.0 0.0 13.7 1.0 6.5 0.7 11.3 10.7 0.6 1174.1 0.1 4.6 1.8 62.0 0.0 0.8 0.8 0.0 183.7 317.9 0.4 0.6 414.6 21.4 131.2 829.9 1.6 24.7 2.5 0.6 0.7 1.1 0.0 119.3 0.5 0.0 0.5 8.0 4.7 0.0 2.2 3.7 0.1 0.2 1.2 13.2 0.5 332.8 0.1 0.9 0.9 SAPCD1 "C6orf26, NG23" ENSG00000228727 "Suppressor APC domain containing 1" Q5SSQ6 6 31762996-31764851 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 28.3" "Cell type enriched" "Detected in single" 15 "Respiratory ciliated cells: 1.5" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.4;U-2 OS: 1.1;U-937: 1.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071699 Approved "Vesicles,Cell Junctions" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 24: NB-4 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" Vesicles "Cell Junctions" "HPA071699: AB_2686433" "unprognostic (9.25e-4)" "unprognostic (1.32e-1)" "unprognostic (3.41e-2)" "unprognostic (3.28e-1)" "unprognostic (9.34e-2)" "unprognostic (8.02e-4)" "unprognostic (1.63e-2)" "unprognostic (3.80e-2)" "unprognostic (2.01e-1)" "unprognostic (8.16e-3)" "unprognostic (1.56e-2)" "unprognostic (2.25e-1)" "unprognostic (8.15e-10)" "unprognostic (2.65e-2)" "unprognostic (4.45e-1)" "unprognostic (3.57e-1)" "unprognostic (7.98e-5)" 2.7 1.1 0.4 0.0 0.4 0.2 2.5 0.5 0.9 2.4 0.4 3.7 0.0 2.5 0.1 2.5 3.9 0.0 1.2 0.4 0.3 7.4 3.1 2.0 0.6 0.4 0.5 3.8 2.1 0.0 6.1 0.1 0.4 6.0 0.2 1.2 2.3 0.1 1.0 28.3 3.9 0.1 0.4 4.8 2.6 3.6 0.4 0.2 2.2 0.0 0.1 2.5 2.2 0.4 0.4 0.0 0.0 0.2 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.1 0.1 0.0 0.5 0.0 0.3 0.2 0.0 0.1 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.7 0.4 0.2 0.2 0.2 0.5 0.0 0.1 0.7 1.4 0.0 0.2 0.0 0.1 0.1 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.3 0.4 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.7 0.1 0.4 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.5 0.9 0.4 0.3 0.4 0.5 0.4 0.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SASH3 "753P9, CXorf9, HACS2, SH3D6C, SLY" ENSG00000122122 "SAM and SH3 domain containing 3" O75995 X 129779949-129795201 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 108.1;intestine: 36.5;lymphoid tissue: 120.7" "Cell type enhanced" "Detected in some" "B-cells: 69.5;dendritic cells: 66.3;Hofbauer cells: 51.3;Kupffer cells: 58.9;Macrophages: 40.0;monocytes: 45.3;NK-cells: 101.0;Plasma cells: 39.8;T-cells: 60.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 164.1;JURKAT: 119.4;MOLT-4: 120.6;NB-4: 89.1;REH: 88.5;U-698: 150.2;U-937: 117.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA001085 Enhanced Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA 14000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Nucleoplasm, Nuclear bodies" "HPA001085: AB_2184289" "unprognostic (1.88e-2)" "unprognostic (5.82e-3)" "unprognostic (1.49e-3)" "prognostic favorable (3.15e-4)" "unprognostic (1.12e-1)" "unprognostic (1.19e-3)" "unprognostic (1.67e-1)" "unprognostic (3.23e-3)" "unprognostic (7.92e-3)" "unprognostic (3.45e-1)" "unprognostic (8.75e-2)" "unprognostic (2.16e-1)" "prognostic unfavorable (6.51e-5)" "unprognostic (3.30e-1)" "unprognostic (3.56e-2)" "unprognostic (3.17e-2)" "unprognostic (1.53e-1)" 8.6 5.6 5.2 61.8 5.6 108.1 4.3 5.4 7.4 3.2 5.1 9.4 11.6 3.1 1.8 3.6 4.9 10.2 2.7 4.8 6.4 3.7 5.9 21.3 120.6 9.6 7.0 1.8 2.5 1.5 2.2 7.5 8.4 4.2 9.9 0.2 7.9 2.2 1.3 2.1 36.5 7.5 7.5 100.3 13.6 1.3 8.4 120.7 3.9 1.7 108.2 15.4 3.0 10.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 164.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.7 0.0 0.0 0.0 58.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 119.4 0.2 13.6 0.0 0.0 120.6 89.1 0.0 0.0 0.0 88.5 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.0 0.1 24.0 0.3 0.0 0.3 0.1 0.1 0.1 35.0 150.2 0.0 117.2 0.0 41.6 135.4 245.5 192.2 195.3 159.1 79.1 108.2 178.9 121.5 90.8 76.9 120.9 128.0 153.3 209.9 55.1 145.6 343.7 5.2 5.6 5.4 7.4 4.8 6.4 9.6 7.0 8.4 7.5 8.4 10.2 0.8 0.0 3.6 0.0 69.5 0.5 0.1 0.0 0.0 0.0 0.5 1.1 1.0 1.5 0.0 0.0 0.0 0.5 66.3 0.1 0.0 0.1 0.1 0.2 0.2 1.2 0.0 13.5 0.2 0.0 0.6 0.9 2.6 0.3 22.2 0.0 3.3 0.9 51.3 0.0 0.2 0.1 0.0 58.9 19.1 0.0 0.3 40.0 0.0 7.5 45.3 0.0 101.0 0.0 0.1 0.0 0.0 0.0 39.8 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.4 0.1 0.0 0.1 1.3 0.5 60.6 0.0 0.1 0.0 SC5D SC5DL ENSG00000109929 Sterol-C5-desaturase O75845 11 121292681-121313410 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" "Lipid biosynthesis, Lipid metabolism, Steroid biosynthesis, Steroid metabolism, Sterol biosynthesis, Sterol metabolism" Oxidoreductase "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 393.6" "Cell type enhanced" "Detected in all" "Hepatic stellate cells: 141.0;Hepatocytes: 307.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA066283, HPA070248" Enhanced Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Nucleoplasm, Endoplasmic reticulum" "Plasma membrane, Cytosol" "HPA066283: AB_2685648, HPA070248: AB_2686240" "unprognostic (4.78e-2)" "unprognostic (7.29e-2)" "unprognostic (2.26e-2)" "unprognostic (2.36e-1)" "unprognostic (3.98e-2)" "prognostic unfavorable (3.30e-4)" "unprognostic (2.79e-2)" "unprognostic (7.96e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (4.03e-2)" "unprognostic (3.18e-2)" "unprognostic (1.01e-1)" "prognostic favorable (1.07e-7)" "unprognostic (4.29e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (1.98e-1)" 28.6 35.3 18.4 12.6 20.4 5.7 56.6 37.1 29.3 20.7 17.6 23.2 48.2 15.1 73.2 39.6 16.5 18.2 22.0 19.9 29.9 49.1 393.6 24.6 13.5 42.9 28.0 16.9 21.5 48.6 15.6 14.7 39.1 101.4 19.9 29.5 22.4 56.6 7.7 13.8 24.7 16.2 32.2 8.8 21.7 24.3 24.6 13.5 23.9 13.0 19.5 21.5 27.1 36.5 26.5 14.3 184.8 39.5 72.1 59.9 27.8 27.8 53.5 18.2 32.4 83.1 95.9 25.4 89.0 32.3 156.6 100.8 59.2 70.9 18.1 12.5 80.0 34.6 73.4 64.4 57.9 24.8 12.5 51.0 57.4 60.4 60.2 15.6 29.8 22.8 25.0 34.6 89.0 27.4 9.4 29.2 59.8 74.4 39.7 13.2 51.0 21.6 133.6 116.5 51.1 28.8 73.4 14.6 38.0 125.4 62.2 38.6 58.3 19.0 29.7 32.5 14.0 6.4 11.2 33.3 7.0 49.5 33.5 7.8 3.7 1.0 3.5 4.9 5.9 4.4 4.7 4.2 6.5 4.1 6.8 6.7 0.3 5.3 3.6 7.7 5.5 2.6 18.4 20.4 37.1 29.3 19.9 29.9 42.9 28.0 39.1 32.2 24.6 36.5 10.4 19.2 31.9 23.8 62.6 9.7 49.9 48.9 14.8 26.8 33.7 12.4 20.8 18.6 40.8 20.2 31.3 15.9 47.5 26.4 5.9 24.1 3.0 11.5 8.8 15.7 14.4 18.1 29.6 28.9 16.7 16.3 18.3 19.6 17.7 11.1 141.0 307.1 21.0 23.5 29.4 15.3 59.0 22.1 17.0 1.3 19.3 17.6 19.6 20.6 15.6 38.7 13.4 27.6 34.0 19.3 18.8 17.0 20.9 50.1 24.1 15.8 18.7 28.3 13.1 12.9 14.7 6.7 12.7 36.2 15.5 18.6 56.5 42.8 13.3 54.4 SCAMP1 SCAMP37 ENSG00000085365 "Secretory carrier membrane protein 1" O15126 5 78360611-78480739 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044753, CAB079009" Supported Uncertain "Nucleoplasm,Vesicles,Cell Junctions" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Cell Junctions" "Nucleoplasm, Vesicles" "CAB079009: , HPA044753: " "unprognostic (8.25e-2)" "unprognostic (3.65e-2)" "unprognostic (1.40e-3)" "unprognostic (5.34e-3)" "unprognostic (2.60e-1)" "unprognostic (2.57e-3)" "unprognostic (5.51e-2)" "unprognostic (3.43e-2)" "unprognostic (1.31e-1)" "unprognostic (8.23e-3)" "unprognostic (2.35e-2)" "unprognostic (2.56e-1)" "prognostic favorable (1.92e-4)" "unprognostic (8.44e-3)" "unprognostic (7.56e-2)" "unprognostic (3.12e-2)" "unprognostic (4.99e-2)" 17.9 22.4 18.4 12.7 20.5 8.5 28.2 24.5 29.1 23.9 23.9 19.6 16.0 25.0 23.2 24.7 29.6 20.2 24.7 20.4 22.4 28.6 17.8 17.8 12.1 18.4 21.5 22.8 25.2 47.1 15.7 23.4 21.4 34.3 22.3 40.2 31.5 29.8 10.6 17.7 15.6 26.6 20.0 13.6 27.9 14.1 23.3 14.6 39.8 16.3 13.4 25.0 11.4 19.0 32.7 23.9 23.4 76.1 35.5 45.5 40.8 30.0 46.1 26.5 56.1 9.3 61.1 48.1 31.4 45.5 65.7 26.2 34.9 57.0 45.9 17.4 32.5 20.5 17.8 20.1 22.7 13.6 16.5 28.6 54.5 27.3 41.2 62.5 41.3 25.0 8.4 33.6 50.9 39.2 25.2 26.7 19.9 14.3 26.0 29.5 38.3 55.3 43.5 38.6 70.9 40.6 27.6 38.5 26.7 24.9 52.5 26.1 36.6 26.3 19.3 30.0 24.2 20.9 29.4 27.6 50.1 50.4 22.6 20.3 11.4 13.2 7.5 12.7 9.3 7.6 8.7 9.2 14.8 6.5 7.1 6.3 6.8 10.3 16.6 4.5 9.1 8.0 18.4 20.5 24.5 29.1 20.4 22.4 18.4 21.5 21.4 20.0 23.3 19.0 59.5 25.6 22.4 45.7 20.3 39.1 31.5 33.6 38.7 72.1 33.4 22.7 36.1 21.5 30.4 40.5 70.9 13.8 21.7 19.1 13.7 24.2 42.2 34.9 30.2 31.4 35.4 12.0 80.0 30.5 24.8 34.3 36.7 34.1 12.0 41.7 27.1 15.7 19.2 32.0 100.1 34.2 20.3 33.7 33.1 15.3 20.2 25.1 30.2 45.0 19.1 47.4 19.6 76.4 60.3 29.8 14.9 28.6 23.9 44.6 14.2 24.7 65.4 68.2 13.1 33.5 25.4 25.6 23.1 30.8 45.3 10.5 21.2 30.8 18.8 33.7 SCAMP4 FLJ33847 ENSG00000227500 "Secretory carrier membrane protein 4" Q969E2 19 1905372-1926013 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043284 Approved Approved "Golgi apparatus,Vesicles,Lipid droplets,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Golgi apparatus, Vesicles" "Lipid droplets, Plasma membrane" "HPA043284: AB_10806501" "unprognostic (1.60e-1)" "unprognostic (3.62e-1)" "unprognostic (5.04e-2)" "prognostic favorable (4.40e-6)" "unprognostic (2.58e-1)" "unprognostic (4.58e-1)" "prognostic unfavorable (1.92e-5)" "unprognostic (2.04e-1)" "unprognostic (1.58e-1)" "unprognostic (2.55e-1)" "unprognostic (3.01e-3)" "unprognostic (5.66e-2)" "prognostic favorable (3.56e-4)" "unprognostic (6.16e-2)" "unprognostic (1.58e-1)" "unprognostic (3.93e-2)" "unprognostic (1.03e-1)" 23.2 27.4 31.1 15.5 39.9 11.4 25.4 41.3 33.3 28.1 33.6 23.3 19.8 26.0 17.5 39.9 38.3 19.5 15.5 28.9 33.1 34.4 28.3 25.5 15.6 51.5 42.9 27.1 36.5 15.8 31.8 18.8 47.7 31.7 9.8 7.4 43.9 20.4 13.9 36.3 20.3 12.3 39.7 25.1 26.4 22.0 40.6 8.3 32.7 5.8 9.4 22.0 25.0 53.5 53.6 53.9 25.7 56.8 50.7 31.7 29.6 35.5 33.1 39.3 46.7 44.9 51.1 22.5 32.1 30.7 23.1 63.7 24.7 38.2 14.5 34.8 21.7 15.8 19.0 44.3 65.6 16.9 23.2 48.8 24.2 34.8 21.2 32.9 27.2 25.2 35.7 25.3 23.3 67.8 21.5 31.6 38.8 31.1 18.6 25.9 18.1 34.6 49.8 47.5 33.8 45.0 23.9 49.9 31.4 18.1 50.6 41.5 29.6 44.8 30.5 81.1 35.7 57.8 62.6 21.0 59.1 26.9 30.1 1.7 4.4 1.9 3.9 4.9 2.0 5.1 2.7 2.6 4.8 3.4 1.5 2.9 2.1 5.8 4.5 12.0 2.3 3.7 31.1 39.9 41.3 33.3 28.9 33.1 51.5 42.9 47.7 39.7 40.6 53.5 16.9 9.6 7.3 12.1 22.9 17.1 25.0 20.8 33.0 19.7 40.0 23.5 3.0 21.5 14.1 49.7 75.0 40.0 59.6 53.0 7.9 20.8 0.8 63.2 23.2 17.8 18.7 11.6 8.3 12.5 38.1 18.2 43.3 42.1 17.2 27.8 15.7 13.4 38.0 21.9 8.0 36.1 20.3 20.1 24.9 1.9 21.8 24.2 21.4 5.6 21.0 29.6 33.0 16.6 18.9 16.1 25.3 17.3 16.0 30.0 47.6 10.1 33.2 52.2 0.0 15.8 15.7 19.0 26.1 30.8 20.2 59.0 20.4 26.9 31.1 28.1 SCEL "FLJ21667, MGC22531" ENSG00000136155 Sciellin O95171 13 77535674-77645263 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 385.5;skin 1: 302.7" "Cell type enriched" "Detected in many" 12 "Alveolar cells type 1: 679.5" "Cancer enhanced" "Detected in many" "thyroid cancer: 17.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 28.6;HaCaT: 54.6;HBEC3-KT: 25.3;OE19: 74.2;RPTEC TERT1: 107.2" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA039737, HPA040154" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA039737: AB_10805485, HPA040154: AB_10795359" "unprognostic (1.18e-1)" "unprognostic (1.17e-1)" "unprognostic (2.00e-1)" "prognostic unfavorable (4.07e-4)" "unprognostic (5.91e-2)" "unprognostic (4.54e-2)" "unprognostic (6.62e-2)" "unprognostic (3.51e-1)" "unprognostic (8.08e-3)" "prognostic unfavorable (1.24e-4)" "unprognostic (4.57e-2)" "prognostic favorable (6.87e-4)" "unprognostic (1.81e-1)" "unprognostic (2.82e-1)" "unprognostic (1.75e-3)" "prognostic unfavorable (1.73e-5)" 3.1 0.1 0.0 0.1 0.1 0.1 19.5 0.1 0.1 69.9 0.0 1.1 0.0 0.1 0.1 385.5 0.3 0.1 0.1 0.0 0.0 0.4 0.1 59.8 0.0 0.1 0.2 0.2 0.2 0.3 0.5 0.8 0.2 0.1 2.0 0.1 57.8 0.0 1.5 302.7 0.1 0.0 0.1 0.0 0.6 2.3 0.1 0.5 2.2 0.0 76.8 0.1 121.6 0.2 16.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.6 0.0 1.8 0.0 0.0 54.6 0.0 25.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 15.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 74.2 14.9 0.0 0.0 0.0 107.2 0.0 2.5 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.1 0.2 0.1 679.5 31.6 0.0 0.0 10.7 0.1 12.9 0.0 0.0 0.0 0.0 0.2 0.0 49.7 0.0 0.0 0.3 0.0 0.7 0.0 3.2 6.6 0.7 0.1 0.2 0.0 0.0 0.2 0.2 0.0 2.0 0.0 1.0 1.3 0.0 0.0 0.0 0.0 0.0 0.6 7.8 8.2 0.0 1.1 20.9 0.0 0.3 1.8 0.0 0.0 1.6 0.0 1.0 1.7 45.5 0.2 0.0 0.0 0.1 0.0 0.1 7.1 0.0 0.0 0.0 1.2 7.9 5.0 48.8 55.8 0.1 0.3 0.8 0.1 2.7 SCHIP1 SCHIP-1 ENSG00000151967 "Schwannomin interacting protein 1" P0DPB3 3 159839861-159897360 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "brain: 81.0;choroid plexus: 28.9;heart muscle: 80.4;skeletal muscle: 101.3;tongue: 92.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 14.2;Horizontal cells: 15.2;Skeletal myocytes: 7.0" "Cancer enriched" "Detected in single" 7 "glioma: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 6.9" "Group enriched" "Detected in many" 46 "dendritic cells: 6.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "AF22: 27.0;AN3-CA: 49.2;HUVEC TERT2: 58.3;NTERA-2: 29.8;SH-SY5Y: 167.0" "HPA003243, HPA069824" Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cell Junctions, Cytosol" "Nucleoplasm, Nuclear bodies" "HPA003243: AB_1079877, HPA069824: AB_2732142" "unprognostic (1.07e-1)" "unprognostic (3.27e-2)" "unprognostic (1.37e-2)" "unprognostic (2.36e-5)" "prognostic favorable (2.80e-4)" "unprognostic (6.25e-2)" "unprognostic (4.56e-3)" "unprognostic (1.11e-1)" "unprognostic (7.81e-2)" "unprognostic (1.38e-1)" "unprognostic (6.45e-3)" "unprognostic (4.67e-2)" "unprognostic (2.12e-1)" "unprognostic (4.66e-4)" "unprognostic (2.30e-1)" "unprognostic (4.52e-2)" "unprognostic (4.96e-1)" 6.1 2.9 46.5 0.2 56.3 0.8 1.2 52.6 55.0 2.5 28.9 11.1 1.0 3.9 0.7 3.4 2.3 1.9 80.4 50.0 48.7 2.5 0.7 2.9 0.5 51.0 48.2 0.5 0.4 0.2 11.8 10.9 52.6 5.6 1.1 3.6 1.9 1.4 101.3 0.4 3.6 5.4 55.6 4.8 4.6 1.9 46.9 0.8 0.8 92.8 0.2 0.7 1.2 81.0 0.1 0.0 27.0 49.2 0.0 0.2 0.0 0.2 0.1 0.1 1.1 0.0 0.0 0.0 1.7 0.0 1.3 0.0 0.0 2.4 0.0 1.4 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.7 1.1 0.3 11.2 0.4 58.3 0.0 0.0 0.1 3.5 0.0 0.0 0.0 29.8 0.0 0.0 0.0 5.5 0.0 1.3 0.0 0.0 167.0 0.0 0.0 0.2 7.0 0.0 3.1 10.9 0.6 1.5 0.4 2.5 2.1 0.0 0.0 0.7 2.0 1.3 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 46.5 56.3 52.6 55.0 50.0 48.7 51.0 48.2 52.6 55.6 46.9 81.0 4.5 6.4 1.7 0.0 0.1 0.4 4.8 2.5 1.2 5.4 0.6 0.8 14.2 0.0 2.2 3.7 2.1 1.5 2.7 0.1 0.0 0.3 0.0 4.4 0.4 6.0 0.0 2.1 0.0 0.2 0.5 1.6 0.0 3.1 0.0 0.1 2.2 0.5 0.2 15.2 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.7 3.6 0.0 0.0 3.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.6 0.0 1.4 3.7 0.6 0.0 7.0 2.9 0.0 0.4 0.4 0.6 0.8 0.2 0.2 0.0 1.4 SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 46.4;kidney: 47.1;placenta: 77.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 334.8;Distal enterocytes: 100.7;Early spermatids: 124.6;Hofbauer cells: 99.9;Paneth cells: 138.6;Proximal enterocytes: 318.4" "Cancer enhanced" "Detected in many" "renal cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 94.3;SK-BR-3: 102.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 2300000 "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Cytosol "HPA020518: AB_1856619, HPA024264: AB_1856621" "unprognostic (3.68e-1)" "unprognostic (4.98e-2)" "unprognostic (5.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (5.98e-2)" "unprognostic (3.64e-5)" "unprognostic (1.31e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic favorable (4.26e-8)" "unprognostic (3.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.13e-2)" "unprognostic (3.18e-1)" 2.9 1.0 3.6 1.3 4.5 1.3 0.9 4.6 5.3 1.3 2.9 18.3 26.7 1.3 0.5 17.9 4.1 2.8 0.3 3.8 4.8 47.1 0.3 4.1 0.6 9.4 6.8 0.7 0.9 1.1 2.6 77.6 9.7 3.2 16.0 2.4 10.7 1.1 0.5 3.6 46.4 1.1 7.1 0.5 19.6 7.1 5.7 0.6 1.1 1.7 4.3 3.5 1.3 12.3 0.2 0.2 0.2 0.8 0.0 0.0 0.3 0.3 0.1 0.1 0.5 0.1 0.5 0.3 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 10.4 0.1 1.3 0.2 0.1 0.4 0.3 0.2 1.4 0.4 0.0 0.2 0.1 0.2 0.4 20.8 0.5 0.5 0.2 1.4 0.2 5.7 3.2 0.3 0.5 0.1 94.3 3.6 4.1 0.2 1.0 102.8 0.1 0.7 10.8 0.6 0.1 0.3 0.8 2.0 0.2 3.4 0.2 0.2 0.1 0.4 0.1 1.2 0.2 0.2 0.3 0.2 0.3 1.1 0.3 0.3 0.2 0.5 0.3 0.3 0.6 0.4 0.3 0.3 0.2 0.1 3.6 4.5 4.6 5.3 3.8 4.8 9.4 6.8 9.7 7.1 5.7 12.3 3.5 0.0 23.6 0.0 0.7 2.8 1.5 1.6 0.6 3.2 3.3 1.7 1.2 4.3 8.5 334.8 0.0 23.8 0.2 100.7 82.2 0.6 124.6 25.5 1.0 6.7 9.1 0.0 0.1 0.2 4.7 2.7 55.5 11.3 39.9 0.0 0.4 0.1 99.9 0.0 0.2 62.9 46.8 3.0 0.5 87.8 0.3 2.8 10.6 15.0 1.7 0.4 0.0 0.0 0.3 8.6 138.6 1.2 1.4 4.7 318.4 3.2 17.2 3.0 0.0 0.9 1.0 3.8 5.5 26.6 6.5 65.8 2.2 0.1 21.4 23.1 SCN1A "FEB3, GEFSP2, HBSCI, NAC1, Nav1.1, SCN1, SMEI" ENSG00000144285 "Sodium voltage-gated channel alpha subunit 1" P35498 2 165984641-166149214 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Autism, Autism spectrum disorder, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 24.7" "Group enriched" "Detected in some" 11 "Excitatory neurons: 409.9;Inhibitory neurons: 494.6;Oligodendrocyte precursor cells: 692.1" "Cancer enriched" "Detected in single" 8 "glioma: 1.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "ASC TERT1: 6.1;Hep G2: 3.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078664 Supported "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "Nuclear bodies" "HPA078664: AB_2686888" "unprognostic (9.25e-2)" "unprognostic (3.97e-2)" "unprognostic (6.88e-2)" "unprognostic (7.44e-2)" "unprognostic (1.50e-1)" "unprognostic (2.74e-1)" "unprognostic (4.70e-2)" "unprognostic (2.88e-1)" "unprognostic (1.67e-1)" "unprognostic (9.59e-2)" "unprognostic (1.23e-1)" "unprognostic (5.03e-9)" "unprognostic (6.92e-2)" "unprognostic (3.69e-2)" "unprognostic (5.06e-3)" "unprognostic (6.93e-1)" 0.0 0.0 4.2 0.0 4.2 0.0 0.0 2.1 24.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 2.1 6.9 0.0 0.0 1.4 0.0 14.2 6.2 0.0 0.0 0.0 2.0 0.0 18.5 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.1 10.9 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.0 0.0 0.9 0.0 0.0 6.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 4.2 2.1 24.7 2.1 6.9 14.2 6.2 18.5 2.2 10.9 10.9 0.0 6.4 33.9 27.4 0.0 0.0 0.0 0.0 0.0 47.4 0.6 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.5 0.0 0.3 1.8 0.0 409.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.3 0.0 494.6 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 18.7 0.0 2.8 0.0 692.1 11.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SCN5A "CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1" ENSG00000183873 "Sodium voltage-gated channel alpha subunit 5" Q14524 3 38548057-38649687 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Calmodulin-binding, Ion channel, Sodium channel, Voltage-gated channel" "Atrial fibrillation, Brugada syndrome, Cardiomyopathy, Disease variant, FDA approved drug targets, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "heart muscle: 42.8" "Cell type enriched" "Detected in some" 5 "Cardiomyocytes: 77.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "LHCN-M2: 27.6;RH-30: 22.8" "Group enriched" "Detected in many" 5 "amygdala: 3.1;basal ganglia: 10.1;hypothalamus: 6.0" "Region enhanced" "Detected in many" "basal ganglia: 5.4" HPA063346 Supported "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "Nucleoplasm, Nucleoli" "HPA063346: " "unprognostic (9.29e-4)" "unprognostic (4.05e-2)" "unprognostic (9.95e-2)" "unprognostic (1.74e-1)" "unprognostic (9.21e-2)" "unprognostic (1.24e-2)" "unprognostic (1.15e-1)" "unprognostic (1.48e-1)" "unprognostic (7.36e-2)" "unprognostic (8.48e-2)" "unprognostic (7.12e-3)" "unprognostic (5.28e-2)" "unprognostic (1.16e-4)" "unprognostic (4.85e-3)" "unprognostic (1.09e-1)" "unprognostic (5.35e-2)" "unprognostic (4.95e-3)" 0.2 0.1 1.9 0.1 1.2 0.2 0.2 0.0 0.7 1.7 0.0 0.2 0.2 0.7 0.0 0.1 0.3 0.1 42.8 0.2 1.5 0.0 0.0 0.1 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.2 0.0 0.3 0.1 2.0 0.2 0.5 1.6 0.1 0.2 0.3 0.2 0.1 0.1 0.3 2.6 0.0 0.2 1.0 0.0 0.4 0.7 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.1 0.4 0.1 0.0 0.2 3.6 0.0 0.0 0.0 1.0 0.5 2.7 0.0 0.4 0.0 1.0 1.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.4 0.0 2.1 2.8 0.4 0.0 0.0 27.6 1.4 0.0 0.0 2.6 0.0 0.0 0.0 22.8 0.0 0.0 3.2 0.4 3.1 0.0 0.0 0.0 0.8 0.0 0.0 5.7 0.0 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.2 0.0 0.7 0.2 1.5 0.0 0.7 0.0 0.2 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 2.7 0.0 0.3 77.1 0.0 0.1 0.0 14.6 0.2 0.0 0.0 0.0 0.1 1.2 0.1 3.2 2.8 0.0 0.0 0.5 0.0 0.3 3.1 0.0 0.3 0.0 0.8 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 6.3 0.3 0.6 0.2 0.0 3.7 0.0 0.6 0.0 1.5 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.9 0.0 7.3 3.1 0.2 1.0 0.0 0.0 0.0 0.1 0.1 0.0 1.4 SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 102.0;Leydig cells: 100.9;Peritubular cells: 159.9;Sertoli cells: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "HDLM-2: 7.9;HMC-1: 4.5;Karpas-707: 5.8;SK-BR-3: 15.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" 4.6 8.6 3.4 3.4 3.0 0.3 10.2 0.1 1.8 7.8 0.0 35.8 3.4 9.0 6.3 10.1 10.9 3.8 20.6 1.1 7.1 1.8 1.2 27.6 0.5 4.0 7.1 45.4 4.9 0.7 1.0 12.3 5.4 11.0 8.5 10.6 6.1 10.1 7.2 2.4 6.8 7.6 2.9 3.2 7.8 5.6 9.8 3.2 1.2 15.0 0.4 4.7 7.1 1.2 0.1 0.1 0.7 0.9 0.2 0.0 0.8 0.7 0.0 1.3 0.0 0.6 0.2 0.4 0.1 0.0 0.3 0.3 0.1 0.1 0.0 7.9 0.5 0.2 1.5 0.6 0.0 0.2 4.5 0.0 0.0 0.4 0.1 0.4 0.0 0.4 1.2 5.8 0.0 1.0 0.8 0.5 1.1 0.3 0.3 0.0 0.5 0.0 0.1 0.8 0.2 0.4 0.3 15.4 0.0 0.3 0.4 0.1 0.4 0.2 1.0 0.7 0.4 1.0 0.3 1.1 0.2 0.2 0.4 1.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.8 3.4 3.0 0.1 1.8 1.1 7.1 4.0 7.1 5.4 2.9 9.8 1.2 1.4 0.0 1.1 1.0 0.0 0.3 0.2 0.0 5.7 21.5 0.2 0.3 16.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 2.4 0.0 0.3 4.1 0.0 0.0 7.7 0.0 0.0 102.0 0.0 0.0 15.9 0.1 9.3 0.0 0.2 0.0 20.9 0.0 0.0 0.0 1.2 4.1 100.9 1.8 5.4 14.0 0.0 4.9 0.0 14.1 0.3 0.1 0.0 159.9 1.2 0.5 0.0 0.5 0.0 1.8 151.2 16.7 26.1 0.5 1.2 1.7 1.1 0.0 0.2 0.3 0.0 0.3 SCN8A "CerIII, CIAT, MED, NaCh6, Nav1.6, PN4" ENSG00000196876 "Sodium voltage-gated channel alpha subunit 8" Q9UQD0 12 51590266-51812864 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 35.0" "Group enriched" "Detected in many" 8 "Excitatory neurons: 336.7;Inhibitory neurons: 280.1;Oligodendrocyte precursor cells: 104.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "cerebral cortex: 35.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.7;ASC TERT1: 13.5;WM-115: 13.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022169, HPA043937, HPA073590" Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cell Junctions" "CAB022169: , HPA043937: , HPA073590: " "unprognostic (2.96e-2)" "unprognostic (8.49e-2)" "unprognostic (6.93e-2)" "unprognostic (3.52e-6)" "unprognostic (8.13e-2)" "unprognostic (1.51e-2)" "unprognostic (1.16e-1)" "unprognostic (7.77e-2)" "unprognostic (5.44e-2)" "unprognostic (1.16e-1)" "unprognostic (4.73e-4)" "unprognostic (1.69e-2)" "unprognostic (1.29e-5)" "unprognostic (4.38e-1)" "unprognostic (1.56e-1)" "unprognostic (2.37e-1)" "unprognostic (4.75e-2)" 0.2 1.0 5.6 0.4 8.9 0.7 0.5 2.5 35.0 0.4 0.0 0.7 0.2 0.4 0.7 0.1 0.2 0.9 0.1 11.4 0.2 0.9 2.6 0.1 0.4 4.2 0.0 0.5 1.6 0.5 6.7 0.1 3.8 0.6 0.9 7.9 0.6 0.2 0.3 0.3 0.2 0.1 0.0 0.6 1.0 1.7 2.4 0.5 0.5 0.1 0.2 0.2 0.2 11.5 1.7 1.3 13.7 0.2 1.8 13.5 0.3 8.0 12.5 9.1 8.5 2.8 1.6 0.4 1.9 9.9 4.4 0.1 2.3 0.0 10.5 1.6 0.8 0.1 0.3 0.3 0.1 0.2 1.1 1.8 0.0 6.5 1.4 3.4 9.8 3.5 0.2 0.2 5.5 1.0 2.5 0.2 4.9 0.9 4.8 0.1 0.7 0.0 0.0 0.5 5.6 2.2 4.5 2.1 0.3 2.1 0.4 0.2 2.8 8.9 6.3 3.3 5.2 0.2 0.1 0.0 1.8 1.9 13.0 0.5 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.0 0.0 5.6 8.9 2.5 35.0 11.4 0.2 4.2 0.0 3.8 0.0 2.4 11.5 1.2 0.0 0.0 27.1 0.0 0.0 0.5 0.0 3.4 16.7 2.6 1.8 1.4 1.5 0.0 0.0 10.4 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.7 1.3 11.4 0.0 336.7 0.5 0.0 0.1 3.1 0.0 0.0 0.7 1.1 4.3 0.0 5.0 280.1 1.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 20.6 0.0 4.7 0.0 104.5 14.2 0.7 0.5 0.7 0.0 0.4 0.0 0.7 0.0 11.2 0.0 0.4 0.3 3.8 10.2 0.1 0.0 0.0 0.3 0.0 0.9 0.3 SCN9A "ETHA, Nav1.7, NE-NA, NENA, PN1" ENSG00000169432 "Sodium voltage-gated channel alpha subunit 9" Q15858 2 166195185-166376001 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 21.9" "Cell type enhanced" "Detected in many" "dendritic cells: 43.2;Hofbauer cells: 67.5;Inhibitory neurons: 48.2;Langerhans cells: 42.8;Oligodendrocyte precursor cells: 133.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 16 "plasmacytoid DC: 23.6" "Lineage enriched" "Detected in single" 26 "dendritic cells: 23.6" "Cell line enhanced" "Detected in many" "BJ: 23.0;BJ hTERT+: 16.8;HHSteC: 19.0;hTERT-RPE1: 15.6" "Region enriched" "Detected in many" 5 "hypothalamus: 9.3" "Low region specificity" "Detected in many" "CAB013679, HPA061843" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Actin filaments, Focal adhesion sites" "CAB013679: , HPA061843: AB_2684625" "unprognostic (2.10e-1)" "unprognostic (2.83e-1)" "unprognostic (1.13e-1)" "unprognostic (8.98e-5)" "unprognostic (1.47e-3)" "unprognostic (9.43e-3)" "unprognostic (2.28e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.64e-1)" "unprognostic (1.45e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (2.30e-5)" "unprognostic (1.69e-3)" "unprognostic (6.74e-2)" "unprognostic (2.46e-2)" "unprognostic (2.46e-1)" 1.7 1.7 5.3 0.9 4.2 2.0 0.6 0.1 3.4 0.6 0.0 3.2 0.5 0.2 0.1 0.5 0.4 1.2 0.4 2.9 21.9 1.7 3.9 2.0 0.6 8.2 19.4 0.3 2.0 0.1 1.5 4.3 12.0 0.3 3.1 0.7 0.4 0.4 0.2 0.7 1.8 2.4 2.2 3.1 0.4 5.1 18.2 1.6 0.3 0.6 0.4 0.5 0.5 1.7 0.0 2.5 0.1 0.0 9.6 7.9 0.0 23.0 16.8 5.2 1.7 0.5 0.1 0.0 0.0 2.8 0.2 0.1 6.5 0.6 8.6 0.0 2.1 1.7 1.8 1.9 19.0 0.1 0.0 0.6 0.2 9.1 1.7 15.6 1.1 1.2 6.1 6.6 0.8 0.0 3.6 0.0 1.9 0.1 0.6 0.8 3.3 9.0 2.4 9.5 1.0 9.5 0.0 0.1 0.3 4.8 0.3 0.0 0.1 0.0 1.5 0.1 0.4 0.1 0.1 0.0 3.2 0.0 2.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.9 0.5 0.1 23.6 0.0 0.1 5.3 4.2 0.1 3.4 2.9 21.9 8.2 19.4 12.0 2.2 18.2 1.7 0.9 12.8 23.8 0.7 1.3 1.0 0.4 0.5 0.6 0.6 0.8 0.9 2.5 8.6 4.4 5.5 0.0 0.3 43.2 9.0 3.9 23.4 2.5 0.1 0.1 5.7 33.0 4.2 15.8 31.5 0.3 2.0 0.0 0.1 3.8 18.1 13.6 9.5 67.5 0.0 48.2 19.3 10.2 1.9 42.8 3.2 1.2 11.3 3.6 2.8 1.0 2.3 0.0 133.7 0.4 12.7 7.8 0.0 1.2 0.3 14.7 11.5 2.2 0.2 0.0 7.8 1.6 1.3 0.4 0.5 0.4 1.1 0.9 4.4 12.9 0.2 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SCRIB "KIAA0147, SCRB1, Vartul" ENSG00000180900 "Scribble planar cell polarity protein" Q14160 8 143790920-143815773 "Disease related genes, Predicted intracellular proteins" "Differentiation, Host-virus interaction, Inhibition of host innate immune response by virus, Inhibition of host interferon signaling pathway by virus, Inhibition of host STAT1 by virus, Inhibition of host STAT2 by virus, Viral immunoevasion" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 100.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015463, CAB022081, HPA023557, HPA064312" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions,Rods & Rings" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "Nucleoplasm, Rods & Rings" "CAB015463: AB_2238926, CAB022081: , HPA023557: AB_2671238, HPA064312: AB_2685242" "unprognostic (1.24e-1)" "unprognostic (1.94e-2)" "unprognostic (7.78e-2)" "unprognostic (8.95e-2)" "unprognostic (3.77e-1)" "unprognostic (3.96e-2)" "unprognostic (1.14e-3)" "unprognostic (1.86e-2)" "unprognostic (2.46e-1)" "unprognostic (2.56e-1)" "unprognostic (8.22e-2)" "unprognostic (1.87e-1)" "unprognostic (2.16e-3)" "unprognostic (3.46e-3)" "unprognostic (1.99e-1)" "unprognostic (1.10e-1)" "unprognostic (1.83e-1)" 18.7 17.1 11.5 7.2 10.8 5.6 23.6 6.0 10.4 45.6 0.0 32.3 9.1 24.7 0.9 100.5 26.0 3.4 24.6 8.7 2.7 27.7 25.4 21.3 4.0 10.7 8.1 23.0 38.8 5.2 24.8 5.0 5.9 28.4 3.4 1.0 40.2 5.2 54.3 68.3 26.5 2.0 4.9 22.9 30.0 26.4 9.0 3.0 24.6 1.7 3.9 27.8 52.6 15.3 55.7 33.1 12.7 20.5 5.1 6.9 33.0 30.9 5.3 11.2 9.1 15.3 29.8 24.2 39.7 7.2 4.6 52.4 7.9 32.9 1.7 30.8 58.5 24.6 30.5 26.1 10.8 13.0 14.8 5.1 29.9 9.4 5.5 5.1 11.5 19.8 42.2 6.4 7.5 93.0 38.1 26.9 15.7 25.0 55.1 44.5 10.6 25.0 5.6 45.5 29.6 27.1 31.4 30.5 33.6 4.5 41.5 28.2 25.7 10.1 64.1 25.2 44.7 31.6 31.0 23.8 13.1 9.5 19.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.5 10.8 6.0 10.4 8.7 2.7 10.7 8.1 5.9 4.9 9.0 15.3 12.3 0.0 9.9 33.0 4.4 8.5 5.0 10.2 13.6 11.3 16.8 17.0 11.1 11.5 8.3 14.7 14.6 11.0 9.7 28.7 3.9 8.6 1.5 14.0 7.7 7.8 13.8 13.7 5.0 9.4 6.3 7.3 29.6 27.3 0.0 17.9 3.6 8.8 6.5 5.0 6.2 17.8 18.3 6.0 4.1 0.7 9.0 6.6 8.8 6.5 5.0 10.0 5.2 12.1 15.2 11.5 22.8 9.8 5.6 9.3 16.9 4.5 9.9 16.0 13.1 12.0 8.7 9.4 10.0 19.9 10.7 5.1 7.3 8.0 23.2 7.1 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SDE2 "C1orf55, FLJ35382" ENSG00000143751 "SDE2 telomere maintenance homolog" Q6IQ49 1 225982702-225999343 "Predicted intracellular proteins" "Cell cycle, Cell division, DNA replication, Mitosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 72.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028467, HPA031255, HPA031256" Approved Supported "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Golgi apparatus, Plasma membrane, Cytosol" "HPA028467: AB_10599192, HPA031255: AB_10601462, HPA031256: AB_10603568" "unprognostic (9.69e-2)" "unprognostic (2.69e-2)" "unprognostic (1.10e-1)" "unprognostic (2.36e-2)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (9.59e-2)" "unprognostic (2.68e-1)" "unprognostic (3.63e-2)" "unprognostic (1.84e-2)" "unprognostic (3.34e-2)" "unprognostic (9.01e-2)" "unprognostic (1.41e-3)" "unprognostic (3.90e-2)" "unprognostic (3.51e-1)" "unprognostic (3.98e-2)" "unprognostic (3.84e-2)" 17.4 8.5 5.5 11.3 7.0 32.9 11.8 6.4 6.6 9.0 4.8 8.3 9.0 11.8 7.8 9.6 7.4 10.5 7.7 4.9 6.0 9.2 14.6 9.2 12.4 6.9 6.6 10.2 9.6 11.1 4.4 11.8 6.6 9.8 9.1 5.1 6.7 7.3 12.7 10.8 9.0 9.8 6.6 10.4 7.7 8.3 6.1 22.8 12.5 9.6 10.6 11.6 7.8 8.4 13.1 9.3 14.9 15.9 10.2 11.3 18.5 13.7 12.9 18.4 14.0 13.7 14.7 19.2 20.9 11.6 7.2 16.5 18.9 11.9 22.2 14.7 15.3 21.1 7.9 12.7 18.6 21.0 24.6 12.5 16.9 19.6 24.6 10.3 12.8 22.6 39.3 22.6 13.7 3.8 29.5 16.6 20.8 20.2 9.8 24.4 19.1 24.9 11.1 9.2 13.3 22.0 15.6 16.9 26.3 11.9 16.6 25.4 12.7 15.6 11.0 20.3 30.4 13.4 10.3 23.4 16.1 12.9 31.5 21.8 6.3 5.9 8.0 6.4 10.8 8.0 8.1 7.8 7.1 7.0 8.1 7.7 18.5 13.5 7.9 8.1 6.7 6.9 5.5 7.0 6.4 6.6 4.9 6.0 6.9 6.6 6.6 6.6 6.1 8.4 36.0 28.9 22.6 4.2 39.9 43.6 17.2 11.2 29.0 6.2 19.8 13.6 9.4 2.8 20.1 9.2 0.0 9.6 29.3 14.3 15.6 6.5 72.8 24.8 15.1 24.8 17.4 56.2 4.7 7.1 10.2 17.8 13.3 35.9 35.5 9.7 12.8 20.6 11.1 15.2 5.0 10.8 16.2 16.4 28.8 20.4 9.9 27.0 19.6 1.9 7.4 12.6 10.3 4.5 8.6 9.7 9.4 6.4 26.6 14.2 9.5 12.7 12.7 8.9 6.6 28.8 23.9 23.9 14.4 26.5 59.1 14.2 23.2 21.0 9.9 18.2 SDHB "SDH, SDH1" ENSG00000117118 "Succinate dehydrogenase complex iron sulfur subunit B" P21912 1 17018722-17054032 "Cancer-related genes, Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Electron transport, Transport, Tricarboxylic acid cycle" Oxidoreductase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 491.5;tongue: 580.6" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 405.5;Proximal tubular cells: 449.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002868, CAB009822, CAB068233, CAB068234, CAB068235" Enhanced Supported "Nucleoplasm,Plasma membrane,Mitochondria" "Intracellular and membrane" NA NA 7900 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Mitochondria "Nucleoplasm, Plasma membrane" "CAB009822: AB_2183458, CAB068233: AB_2665638, CAB068234: AB_2665639, CAB068235: AB_2665640, HPA002868: AB_1079889" "unprognostic (1.06e-1)" "unprognostic (2.86e-2)" "unprognostic (2.19e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.79e-3)" "unprognostic (1.58e-1)" "unprognostic (3.02e-1)" "unprognostic (1.19e-1)" "unprognostic (8.45e-2)" "unprognostic (5.51e-2)" "unprognostic (3.93e-2)" "prognostic favorable (2.93e-7)" "unprognostic (1.46e-1)" "unprognostic (2.75e-1)" "unprognostic (7.82e-2)" "unprognostic (3.82e-2)" 85.8 95.7 68.0 59.0 72.2 94.6 68.7 80.6 84.3 56.8 81.1 134.3 163.0 56.0 71.0 77.4 59.8 48.0 302.8 69.9 76.9 228.0 336.1 56.1 75.3 74.8 71.4 44.4 80.3 144.3 42.8 57.6 73.8 55.7 132.4 62.9 74.0 60.5 491.5 55.6 121.9 70.4 73.9 60.5 92.8 64.4 74.9 62.7 64.3 580.6 84.2 71.3 52.0 78.9 157.3 152.7 72.2 107.8 141.6 135.2 95.9 122.4 145.2 254.3 227.7 216.8 183.1 206.8 159.3 156.4 176.1 180.1 290.7 226.8 284.8 128.7 280.6 183.4 149.2 168.2 172.8 276.0 135.6 140.4 154.9 224.5 370.1 138.7 183.6 176.5 165.2 236.9 179.6 129.5 182.4 175.1 70.4 224.6 302.6 146.1 142.5 265.4 252.4 88.7 157.5 86.0 172.3 216.3 392.3 76.4 131.1 169.1 94.9 115.8 131.0 206.4 176.0 98.9 133.3 198.6 170.4 438.5 128.3 68.7 149.8 149.5 71.4 206.5 70.7 89.9 81.0 77.5 186.8 81.1 73.5 74.8 174.3 85.3 185.7 89.3 113.8 116.1 68.0 72.2 80.6 84.3 69.9 76.9 74.8 71.4 73.8 73.9 74.9 78.9 48.2 64.1 47.4 20.9 57.4 52.1 93.3 199.8 40.5 31.5 45.2 49.4 405.5 101.5 97.0 47.8 14.6 107.1 48.3 176.1 354.1 134.3 220.3 48.7 38.2 54.7 48.6 77.3 27.7 149.2 142.2 62.0 46.9 45.5 66.6 39.9 46.8 226.0 177.4 37.0 32.1 103.1 116.0 88.7 67.9 30.5 57.8 78.4 64.0 29.0 123.1 78.3 48.4 15.6 24.6 111.5 218.3 67.7 62.2 74.4 300.5 449.0 79.8 53.8 39.5 57.1 191.6 148.9 71.5 72.9 54.6 121.8 46.8 69.3 162.0 110.9 SEC16B "LZTR2, PGPR-p117, RGPR, Sec16S" ENSG00000120341 "SEC16 homolog B, endoplasmic reticulum export factor" Q96JE7 1 177923956-177984303 "Predicted intracellular proteins" "ER-Golgi transport, Peroxisome biogenesis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 28.4;liver: 36.4" "Cell type enhanced" "Detected in many" "Hepatocytes: 66.3;Late spermatids: 50.4;Proximal enterocytes: 34.8" "Not detected" "Not detected" "Region enhanced" "Detected in some" "cerebral cortex: 2.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 6.6;CAPAN-2: 7.2;EFO-21: 5.4;HDLM-2: 5.8;Karpas-707: 4.8;RPMI-8226: 6.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA054292, HPA072913" Enhanced Approved "Endoplasmic reticulum,Plasma membrane,Actin filaments" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "Actin filaments" "HPA054292: AB_2682439, HPA072913: AB_2732213" "unprognostic (2.31e-1)" "unprognostic (1.90e-1)" "unprognostic (6.78e-3)" "unprognostic (6.07e-2)" "unprognostic (1.69e-1)" "unprognostic (1.33e-1)" "unprognostic (6.39e-3)" "unprognostic (1.22e-1)" "unprognostic (2.27e-2)" "unprognostic (1.50e-2)" "unprognostic (4.76e-3)" "unprognostic (2.43e-1)" "unprognostic (7.34e-4)" "unprognostic (6.67e-2)" "unprognostic (1.66e-1)" "unprognostic (1.37e-1)" "unprognostic (1.05e-1)" 4.0 2.5 0.5 1.1 1.1 0.3 3.2 0.0 2.9 3.0 0.0 3.6 28.0 3.5 2.0 2.0 3.5 4.3 2.6 0.8 0.1 3.4 36.4 2.4 1.1 0.0 0.3 4.2 9.0 0.5 1.4 0.8 0.1 1.6 4.0 5.7 3.6 2.1 9.3 2.7 28.4 2.7 0.0 5.8 8.7 1.4 0.3 0.4 2.1 3.1 0.9 1.4 1.1 1.2 1.9 1.5 0.1 1.5 1.9 6.6 0.0 1.5 0.5 0.1 0.7 1.0 7.2 0.6 5.4 1.2 0.1 0.0 0.4 0.2 0.0 5.8 0.1 0.0 0.0 3.4 0.1 0.1 0.0 3.8 0.5 0.2 0.0 0.2 2.2 0.0 0.0 4.8 3.9 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.6 6.5 0.1 0.1 0.6 1.2 0.1 0.2 0.8 0.0 0.1 1.3 0.7 1.0 0.2 0.6 0.0 1.5 0.7 0.1 2.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.1 0.0 2.9 0.8 0.1 0.0 0.3 0.1 0.0 0.3 1.2 7.7 0.0 2.0 2.9 0.7 0.3 0.3 0.4 1.8 1.3 6.3 1.8 0.5 7.2 1.9 1.8 2.1 0.5 0.0 0.9 0.0 0.6 10.1 2.3 1.6 3.9 3.6 0.0 15.8 1.1 0.0 1.9 9.2 2.7 1.3 1.9 3.6 66.3 0.6 11.8 4.8 4.6 0.0 3.2 0.4 50.4 2.5 0.7 1.8 3.7 0.6 1.4 0.0 1.0 1.3 1.1 5.2 1.2 2.9 0.1 34.8 3.1 3.3 4.7 0.0 2.7 1.0 0.3 0.8 0.6 1.0 0.0 0.3 0.1 5.4 0.2 SEMA3C "SEMAE, SemE" ENSG00000075223 "Semaphorin 3C" Q99985 7 80742538-80922359 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 92.2;Breast myoepithelial cells: 93.5;Fibroblasts: 109.6;Ionocytes: 91.6;Oligodendrocytes: 223.7;Respiratory ciliated cells: 103.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 49.6" "Lineage enriched" "Detected in many" 9 "granulocytes: 49.6" "Cell line enhanced" "Detected in many" "GAMG: 252.7;RT4: 238.3;T-47d: 267.0;U-2197: 349.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA042418 Approved "Golgi apparatus,Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 13000 "Cluster 46: Basophils - DNA binding" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Cytosol" "Plasma membrane" "HPA042418: AB_10797389" "unprognostic (1.93e-2)" "unprognostic (2.54e-3)" "unprognostic (4.94e-1)" "unprognostic (9.86e-2)" "unprognostic (6.74e-2)" "prognostic unfavorable (5.72e-5)" "unprognostic (9.28e-3)" "unprognostic (1.91e-3)" "unprognostic (1.39e-2)" "unprognostic (9.01e-2)" "prognostic unfavorable (4.08e-5)" "unprognostic (2.07e-2)" "unprognostic (1.55e-3)" "unprognostic (1.78e-2)" "unprognostic (1.57e-1)" "unprognostic (1.37e-2)" "unprognostic (1.92e-2)" 53.8 9.5 4.9 12.7 8.1 0.8 57.3 9.1 5.5 53.0 2.6 38.4 10.6 42.7 23.1 20.5 15.4 30.0 22.1 11.0 12.7 10.0 1.3 18.4 1.0 15.0 8.0 48.5 2.6 0.8 3.7 6.0 17.5 66.6 31.3 1.0 27.3 42.3 19.3 17.9 14.1 44.4 10.0 22.2 20.6 12.9 8.4 1.4 1.8 34.3 1.1 69.8 14.4 12.8 6.6 77.0 156.4 0.6 35.2 82.5 0.3 51.8 59.7 25.9 32.5 12.4 144.7 0.0 2.1 17.7 252.7 31.2 0.7 47.0 42.4 0.1 15.8 9.9 63.6 0.7 41.3 0.7 0.2 36.1 32.3 63.6 62.0 220.2 0.5 0.0 0.5 0.1 46.4 113.7 0.2 0.3 1.4 22.2 12.2 0.1 75.5 1.2 142.9 238.3 0.8 82.4 145.7 38.9 9.5 66.3 267.0 0.2 125.2 140.1 64.2 349.2 93.9 1.2 0.0 0.1 52.8 0.0 142.3 49.6 5.7 0.9 0.0 2.4 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 2.6 0.0 1.9 3.3 0.0 1.7 4.9 8.1 9.1 5.5 11.0 12.7 15.0 8.0 17.5 10.0 8.4 12.8 7.4 9.6 8.9 3.3 0.3 26.4 41.8 92.2 10.8 0.3 15.8 93.5 38.2 1.5 39.8 7.3 6.2 0.5 1.7 56.1 1.9 3.8 0.5 20.3 11.9 7.7 6.0 4.6 41.7 6.6 1.3 109.6 17.9 34.4 5.1 13.2 1.1 0.0 8.8 0.0 16.7 15.7 91.6 3.1 14.9 2.3 7.8 9.0 55.2 20.6 8.3 1.5 1.0 3.0 223.7 68.2 12.4 52.3 0.0 53.7 12.5 0.4 103.0 0.6 0.0 38.8 17.3 0.7 2.7 3.0 18.9 0.3 1.5 9.9 30.4 70.0 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA4B "KIAA1745, MGC131831, SEMAC, SemC" ENSG00000185033 "Semaphorin 4B" Q9NPR2 15 90160604-90229679 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 124.4" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 16.9;naive B-cell: 14.9;neutrophil: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "CAPAN-2: 182.4;RPTEC TERT1: 111.1;RT4: 124.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013372 Approved Approved "Nucleoplasm,Vesicles,Cell Junctions" NA NA 61000000 "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Cell Junctions" "Nucleoplasm, Vesicles" "HPA013372: AB_1856670" "unprognostic (3.33e-2)" "unprognostic (5.96e-2)" "unprognostic (2.23e-2)" "unprognostic (2.50e-2)" "unprognostic (7.78e-2)" "unprognostic (4.48e-2)" "unprognostic (6.34e-3)" "prognostic unfavorable (1.25e-4)" "unprognostic (2.04e-1)" "unprognostic (9.31e-2)" "unprognostic (1.58e-3)" "unprognostic (4.67e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (3.57e-2)" "unprognostic (7.09e-2)" 11.9 37.6 20.3 18.0 21.9 9.8 22.5 18.8 21.6 35.1 12.8 50.2 30.2 17.1 8.2 124.4 22.6 17.1 24.9 17.3 21.0 47.7 43.2 20.5 12.0 23.5 24.0 21.6 38.5 18.1 18.6 18.3 21.4 31.4 12.1 27.1 41.2 17.6 7.8 50.9 34.7 13.3 21.0 30.3 32.2 10.7 22.9 13.2 34.2 7.9 13.0 42.2 59.8 26.8 21.2 56.3 4.2 13.2 3.8 2.6 30.4 6.4 13.9 7.8 8.3 7.0 182.4 14.9 69.2 4.7 45.0 97.8 3.7 91.2 6.4 85.4 11.7 19.7 13.5 9.4 15.1 2.6 8.7 10.8 39.1 8.5 17.5 32.5 8.8 4.4 9.6 23.0 4.3 15.6 5.4 8.4 18.7 46.8 51.1 6.4 3.1 33.1 111.1 124.0 13.3 13.5 22.3 35.4 8.5 9.3 24.7 6.0 20.0 6.3 11.4 13.1 14.5 33.0 43.2 7.5 58.8 16.1 6.3 0.0 2.4 0.3 0.9 1.4 0.6 16.9 0.5 0.5 1.2 14.9 0.5 0.6 5.1 0.4 2.8 0.2 0.2 1.5 20.3 21.9 18.8 21.6 17.3 21.0 23.5 24.0 21.4 21.0 22.9 26.8 1.8 16.0 22.5 67.3 29.2 65.0 40.0 51.4 23.9 5.7 29.1 18.9 7.8 8.6 44.6 16.5 25.0 13.9 2.4 47.8 3.9 27.3 0.9 15.6 19.6 4.4 4.2 4.0 23.5 35.5 74.5 6.4 34.1 28.3 0.0 8.6 4.6 16.8 13.3 16.8 28.2 17.5 18.3 6.9 7.5 1.2 13.1 5.5 5.4 2.8 5.3 25.1 1.0 8.0 8.3 44.7 26.1 12.0 8.0 46.9 19.6 4.5 22.6 48.3 19.7 5.7 15.3 0.7 3.2 65.3 57.1 12.4 4.3 5.2 20.2 52.0 SEMA4F "SEMAM, SEMAW" ENSG00000135622 "Ssemaphorin 4F" O95754 2 74654228-74683853 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 44.5;Inhibitory neurons: 22.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA064095, HPA065969" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane, Centrosome" "HPA064095: AB_2732710, HPA065969: AB_2685590" "unprognostic (9.69e-2)" "unprognostic (8.88e-3)" "unprognostic (1.58e-2)" "prognostic unfavorable (5.94e-5)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.23e-2)" "unprognostic (1.61e-3)" "unprognostic (6.95e-2)" "unprognostic (9.01e-3)" "unprognostic (6.53e-2)" "unprognostic (2.21e-2)" "unprognostic (1.54e-1)" "prognostic unfavorable (9.74e-6)" "unprognostic (2.60e-2)" "unprognostic (8.08e-2)" "prognostic favorable (6.94e-4)" "unprognostic (4.69e-2)" 3.2 2.3 5.4 0.9 7.0 0.4 3.2 3.2 8.2 4.1 0.1 2.5 0.5 3.6 1.7 1.3 3.3 0.8 2.7 8.0 6.3 3.5 1.0 2.5 1.5 4.2 2.1 5.3 2.6 3.0 7.2 0.9 3.9 3.1 1.0 4.7 2.7 1.4 1.4 1.9 2.1 1.6 1.5 2.6 2.2 4.1 8.1 1.2 3.1 1.3 1.4 2.6 3.2 3.8 6.1 3.4 3.7 5.5 5.8 3.3 2.6 3.9 8.9 7.4 6.5 1.4 3.3 2.3 5.0 6.2 14.4 1.9 6.7 5.7 7.5 5.3 7.0 4.4 1.4 3.8 2.3 1.0 5.4 2.6 6.0 4.9 2.4 14.1 2.9 4.4 0.2 0.2 4.8 2.1 3.3 0.8 2.6 2.7 4.0 0.0 5.4 0.0 6.0 2.6 2.9 5.8 7.0 1.8 6.5 5.0 2.6 0.7 4.9 11.5 5.8 2.9 7.1 5.2 5.6 0.3 13.4 0.3 5.6 0.3 0.1 0.7 1.9 0.0 1.2 1.1 1.1 1.7 0.0 0.8 1.1 1.3 0.3 1.0 0.2 0.0 0.9 0.8 5.4 7.0 3.2 8.2 8.0 6.3 4.2 2.1 3.9 1.5 8.1 3.8 2.2 0.0 6.5 4.9 2.7 0.4 1.8 1.8 2.2 8.8 1.8 2.5 2.4 5.7 4.8 5.5 12.5 0.8 1.4 0.7 1.9 2.1 3.2 0.6 0.6 2.2 7.2 0.8 44.5 1.6 2.4 3.3 1.5 1.0 2.5 3.0 3.3 0.6 0.8 11.8 22.7 0.6 2.0 0.0 0.7 3.7 0.9 0.7 0.0 4.7 1.5 3.3 4.1 4.5 5.8 2.7 1.4 1.5 0.7 1.3 0.4 0.3 1.3 6.7 6.6 3.1 1.4 5.6 11.2 0.5 0.4 0.4 3.5 0.5 1.0 1.6 SEMA6C KIAA1869 ENSG00000143434 "Semaphorin 6C" Q9H3T2 1 151131685-151146664 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "skeletal muscle: 322.9;tongue: 96.9" "Cell type enhanced" "Detected in many" "Adipocytes: 12.9;Cardiomyocytes: 19.1;Cone photoreceptor cells: 20.9;Inhibitory neurons: 13.7;Skeletal myocytes: 12.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 14.1;HUVEC TERT2: 24.8;TIME: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA076150, HPA077625" Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1500000 "Cluster 33: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Plasma membrane" "Nucleoli fibrillar center, Cytosol" "HPA076150: , HPA077625: " "unprognostic (6.97e-2)" "unprognostic (8.40e-2)" "unprognostic (1.56e-3)" "prognostic unfavorable (3.27e-4)" "unprognostic (2.79e-1)" "unprognostic (2.88e-2)" "unprognostic (3.00e-2)" "unprognostic (1.24e-2)" "unprognostic (5.66e-3)" "unprognostic (4.25e-2)" "prognostic favorable (3.06e-5)" "unprognostic (3.72e-2)" "unprognostic (1.67e-2)" "unprognostic (6.12e-2)" "unprognostic (9.49e-2)" "unprognostic (1.10e-1)" "unprognostic (1.85e-1)" 8.8 2.8 7.7 1.8 6.7 1.2 7.9 21.9 9.4 12.0 1.0 7.6 13.7 10.5 1.4 5.5 10.7 3.7 38.8 7.9 5.4 12.1 12.4 5.1 1.7 5.0 5.0 14.8 3.6 2.1 13.4 1.9 4.9 8.3 1.8 5.2 8.5 2.3 322.9 8.9 10.8 6.2 2.2 3.0 5.4 32.2 7.3 2.2 4.7 96.9 0.9 8.4 8.8 5.3 0.9 1.0 14.1 5.4 5.8 1.9 1.3 1.0 0.5 0.9 1.3 0.3 0.6 0.7 4.0 3.3 2.0 1.4 1.3 0.5 0.8 1.3 4.2 7.7 0.7 1.2 0.8 0.1 2.7 3.3 1.7 1.2 0.6 2.8 24.8 4.1 0.7 0.7 2.3 0.5 1.3 1.0 6.3 0.2 1.7 9.0 3.1 0.3 0.5 0.4 7.1 9.3 1.3 0.6 1.2 3.5 1.6 1.3 11.8 2.3 3.3 3.5 0.6 5.9 1.2 6.1 0.6 0.3 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 6.7 21.9 9.4 7.9 5.4 5.0 5.0 4.9 2.2 7.3 5.3 12.9 0.0 2.8 3.9 1.0 1.7 0.8 0.3 0.6 5.7 1.9 3.0 19.1 1.5 0.8 0.0 20.9 0.2 0.6 0.1 0.0 0.3 0.6 0.4 2.8 10.2 0.0 0.8 6.7 0.4 0.6 4.4 0.5 0.4 0.0 9.9 6.8 5.3 0.4 6.7 13.7 0.3 0.0 2.5 0.7 3.1 5.6 0.5 1.8 4.7 0.4 1.9 1.0 5.5 1.5 0.4 0.0 2.6 1.9 0.5 3.3 2.9 0.3 7.5 0.0 12.0 2.9 3.3 1.2 0.5 1.0 0.1 0.8 0.5 0.8 0.5 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SEPTIN2 "DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2" ENSG00000168385 "Septin 2" Q15019 2 241315100-241354027 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 89.9;Cardiomyocytes: 133.5;Cytotrophoblasts: 135.9;Extravillous trophoblasts: 190.1;Hofbauer cells: 136.8;Syncytiotrophoblasts: 139.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017190, HPA018481" Supported Enhanced "Nucleoplasm,Plasma membrane,Actin filaments,Cytokinetic bridge" Yes No 3300000 "Cluster 27: Non-specific - Gene expression" "Cluster 57: Non-specific - Angiogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoplasm, Plasma membrane, Cytokinetic bridge" "CAB017190: , HPA018481: AB_1856684" "unprognostic (6.31e-2)" "unprognostic (5.27e-2)" "unprognostic (2.95e-2)" "unprognostic (4.03e-2)" "prognostic favorable (8.21e-4)" "unprognostic (3.32e-1)" "prognostic unfavorable (3.66e-4)" "unprognostic (1.96e-3)" "unprognostic (1.83e-2)" "unprognostic (5.69e-2)" "unprognostic (1.11e-3)" "unprognostic (3.16e-1)" "unprognostic (9.58e-3)" "unprognostic (8.11e-2)" "unprognostic (9.53e-2)" "unprognostic (1.40e-1)" "unprognostic (2.17e-2)" 246.0 155.0 192.8 159.7 216.1 125.3 177.2 208.8 220.6 233.8 183.2 179.7 140.8 209.0 176.7 161.1 168.7 193.8 211.8 180.5 209.6 212.6 117.1 184.5 157.2 227.2 203.3 221.7 214.2 220.1 112.7 217.3 232.2 186.1 188.6 114.0 163.3 218.2 160.6 119.0 154.8 253.1 224.1 164.9 152.6 145.0 198.3 141.8 224.6 163.5 180.5 221.0 116.7 245.3 245.1 207.7 561.7 370.8 511.5 555.0 289.1 517.3 508.9 329.1 417.2 118.7 258.4 96.1 119.4 599.0 176.7 209.6 377.7 347.9 535.5 241.9 262.2 388.9 200.5 444.5 311.6 374.4 228.0 495.1 224.8 275.0 259.1 369.8 576.2 240.9 357.4 138.0 491.9 171.5 226.7 227.3 412.5 215.2 152.8 216.2 707.4 204.7 483.5 359.9 401.4 270.0 363.0 245.7 353.0 397.9 146.9 333.4 555.5 399.2 166.2 392.9 320.6 267.7 251.9 340.9 344.7 225.1 571.6 172.0 165.0 98.3 101.0 184.1 125.1 87.4 97.9 104.2 183.8 77.2 84.4 89.6 58.9 191.4 144.8 138.7 108.0 241.2 192.8 216.1 208.8 220.6 180.5 209.6 227.2 203.3 232.2 224.1 198.3 245.3 89.9 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 133.5 0.0 0.0 0.0 0.0 135.9 39.9 0.0 0.0 0.0 0.0 0.0 0.0 25.3 0.0 0.0 0.0 0.0 190.1 50.4 0.0 0.0 0.0 0.0 0.0 0.0 136.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.7 0.0 0.0 0.0 0.0 139.0 6.5 0.0 0.0 0.0 SEPTIN3 "SEP3, SEPT3" ENSG00000100167 "Septin 3" Q9UH03 22 41969475-41998221 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 233.7" "Cell type enriched" "Detected in some" 5 "Extravillous trophoblasts: 27.9" "Group enriched" "Detected in many" 5 "glioma: 24.6;melanoma: 11.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 26.6;Daudi: 22.3;SCLC-21H: 71.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003548, CAB017633" Supported Supported Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 38: Extravillous trophoblasts - Unknown function" "Nucleoplasm, Plasma membrane" "Actin filaments" "CAB017633: AB_2301476, HPA003548: AB_1079908" "unprognostic (2.10e-1)" "unprognostic (4.67e-2)" "unprognostic (1.16e-2)" "prognostic unfavorable (1.78e-4)" "unprognostic (4.56e-2)" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (2.37e-1)" "unprognostic (2.67e-3)" "unprognostic (3.09e-2)" "unprognostic (1.30e-2)" "unprognostic (6.30e-2)" "unprognostic (2.51e-2)" "unprognostic (9.15e-2)" "unprognostic (6.68e-2)" "unprognostic (5.50e-2)" "unprognostic (1.04e-1)" 0.2 4.6 134.7 0.4 160.5 0.1 1.3 82.4 233.7 0.2 30.5 0.8 0.3 0.2 1.4 0.2 0.1 0.4 0.2 167.0 89.5 0.3 0.1 0.7 0.5 86.2 73.4 0.2 1.2 18.6 7.8 5.7 83.8 1.3 0.5 28.4 0.4 0.0 0.1 1.6 0.4 0.3 56.9 0.2 0.7 2.1 91.4 0.9 0.8 0.2 0.5 0.3 0.4 150.7 1.5 1.7 26.6 20.1 0.3 0.0 13.3 0.3 0.3 1.8 0.8 0.4 3.1 22.3 0.7 0.2 11.4 0.1 14.0 0.1 0.7 9.2 4.6 0.1 0.5 0.0 0.2 0.0 0.9 0.2 1.0 0.1 0.0 0.0 0.0 12.1 0.0 3.4 0.0 2.4 3.7 0.2 18.2 0.2 0.7 17.9 0.0 1.3 0.0 2.7 71.4 14.8 10.9 0.1 18.2 2.5 2.6 6.7 0.0 0.0 9.2 0.9 1.0 14.1 13.1 0.2 0.3 9.0 2.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 134.7 160.5 82.4 233.7 167.0 89.5 86.2 73.4 83.8 56.9 91.4 150.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.0 SEPTIN7 "CDC10, CDC3, SEPT7, SEPT7A" ENSG00000122545 "Septin 7" Q16181 7 35800932-35907105 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation, Mitosis, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 570.9" "Group enriched" "Detected in some" 4 "Adipocytes: 192.1;Cardiomyocytes: 227.0;Cytotrophoblasts: 171.4;dendritic cells: 196.6;Extravillous trophoblasts: 198.2;Fibroblasts: 153.5;Hofbauer cells: 191.0;Smooth muscle cells: 190.0;Syncytiotrophoblasts: 124.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023309, HPA029524" Enhanced Approved "Nucleoli,Plasma membrane,Actin filaments,Midbody,Cytosol" Yes No 4300000 "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" "Actin filaments" "Nucleoli, Plasma membrane, Midbody, Cytosol" "HPA023309: AB_10600093, HPA029524: AB_10601573" "unprognostic (7.91e-3)" "unprognostic (6.89e-3)" "unprognostic (9.49e-2)" "unprognostic (1.27e-1)" "unprognostic (1.04e-1)" "unprognostic (2.22e-2)" "prognostic unfavorable (2.37e-4)" "unprognostic (2.00e-2)" "unprognostic (4.43e-2)" "unprognostic (7.13e-2)" "unprognostic (3.56e-2)" "unprognostic (7.66e-2)" "prognostic unfavorable (2.78e-4)" "unprognostic (2.86e-2)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (2.43e-3)" 127.1 95.1 352.6 98.8 386.1 131.0 99.5 334.3 570.9 111.5 289.5 116.4 55.7 126.5 121.5 106.6 84.1 117.5 172.1 344.1 341.6 82.9 76.9 98.6 150.9 337.4 355.9 138.2 37.0 81.1 62.6 143.5 339.1 93.9 94.8 119.5 50.3 95.5 82.9 105.0 74.9 145.2 345.1 108.3 59.4 70.3 367.7 159.0 78.2 104.3 149.7 125.0 86.9 411.9 198.1 94.3 232.0 153.2 256.7 263.1 119.3 248.6 228.6 206.7 177.0 147.7 148.9 186.2 164.2 254.9 274.9 146.3 166.3 166.4 294.0 127.8 88.4 149.8 123.4 80.8 149.4 182.7 157.7 171.7 127.1 163.8 159.4 215.6 221.0 143.3 120.1 141.9 341.6 92.8 185.6 304.3 249.7 183.1 132.6 188.3 220.9 107.6 202.6 146.1 124.3 217.4 173.5 220.1 151.8 377.1 163.1 198.7 187.3 207.2 246.7 129.9 278.5 165.9 163.4 470.2 132.4 301.2 449.3 266.8 86.0 150.1 214.8 100.1 220.7 165.6 151.5 199.6 100.8 155.5 134.4 171.2 160.9 298.7 110.5 71.0 147.4 241.7 352.6 386.1 334.3 570.9 344.1 341.6 337.4 355.9 339.1 345.1 367.7 411.9 192.1 0.0 0.0 0.0 41.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 227.0 0.0 0.0 0.0 0.0 171.4 196.6 0.0 0.0 0.0 0.0 0.0 0.0 40.1 0.0 0.0 0.0 0.0 198.2 153.5 0.0 0.0 0.0 0.0 0.0 0.0 191.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 190.0 0.0 0.0 0.0 0.0 124.2 30.4 0.0 0.0 0.0 SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 235.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.3;Distal enterocytes: 530.1;Ductal cells: 735.4;Pancreatic endocrine cells: 457.4;Paneth cells: 465.1;Proximal enterocytes: 422.0;Syncytiotrophoblasts: 446.6;Urothelial cells: 432.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 305.6;HaCaT: 349.2;HBEC3-KT: 553.0;hTCEpi: 307.8;RT4: 381.9;SK-BR-3: 311.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" 6.5 23.8 1.2 15.0 1.4 8.1 33.8 1.5 1.2 68.9 2.9 111.0 118.7 15.3 21.4 120.7 18.9 59.1 3.2 1.0 1.7 114.1 235.5 20.9 3.5 1.8 2.2 0.9 37.7 45.8 9.7 44.5 1.9 56.6 56.2 0.1 151.0 62.1 76.8 53.5 105.6 2.6 1.6 3.4 90.7 4.9 5.8 8.8 28.4 24.5 9.5 116.5 39.3 1.8 87.3 20.5 17.7 57.0 37.3 50.4 48.2 162.8 119.5 10.6 13.1 31.1 305.6 57.0 209.5 154.6 12.9 349.2 2.3 553.0 2.1 5.5 13.2 0.0 17.2 16.6 42.0 0.5 64.1 46.0 307.8 66.5 144.2 45.5 6.7 6.9 2.6 0.5 18.2 14.2 2.1 2.0 18.3 172.1 42.4 0.4 34.8 19.5 57.9 381.9 7.6 42.4 41.7 311.0 6.5 8.5 182.8 9.9 40.7 2.8 13.0 1.8 3.4 2.9 2.1 2.6 1.4 1.6 13.7 0.0 2.4 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 10.4 0.0 0.6 1.2 1.4 1.5 1.2 1.0 1.7 1.8 2.2 1.9 1.6 5.8 1.8 2.2 16.0 8.9 0.0 2.7 12.4 108.7 374.7 37.0 0.0 162.9 72.9 0.7 138.7 173.3 117.7 0.0 466.3 4.2 530.1 72.4 735.4 6.4 61.6 18.2 8.8 116.6 3.6 0.4 326.3 91.2 5.4 80.0 140.7 0.0 1.6 5.7 54.5 47.5 0.0 0.4 195.0 183.1 5.1 5.0 12.9 2.1 13.1 40.9 1.0 48.4 0.6 0.0 0.0 0.2 457.4 465.1 0.0 0.1 192.2 422.0 71.0 54.3 0.0 0.0 23.5 19.3 0.7 9.5 30.8 21.2 446.6 3.5 0.1 145.7 432.5 SERINC5 "C5orf12, TPO1" ENSG00000164300 "Serine incorporator 5" Q86VE9 5 80111651-80256048 "Predicted membrane proteins, Transporters" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity, Lipid biosynthesis, Lipid metabolism, Phospholipid biosynthesis, Phospholipid metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 223.2;Oligodendrocytes: 222.5;Urothelial cells: 254.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 56.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037898, HPA037899" Supported Supported "Vesicles,Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "Vesicles, Centrosome" "HPA037898: AB_10673649, HPA037899: AB_2675727" "unprognostic (2.95e-1)" "unprognostic (1.80e-1)" "unprognostic (4.98e-3)" "unprognostic (1.08e-2)" "unprognostic (5.05e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-2)" "unprognostic (8.00e-2)" "unprognostic (2.10e-1)" "unprognostic (2.68e-2)" "unprognostic (7.71e-2)" "unprognostic (1.62e-1)" "unprognostic (1.40e-2)" "unprognostic (4.81e-2)" "unprognostic (8.09e-2)" "unprognostic (4.93e-2)" "unprognostic (9.17e-2)" 12.9 34.8 19.2 9.8 31.0 6.3 11.8 27.2 20.7 16.4 17.4 28.3 9.2 9.2 21.1 17.6 16.2 14.2 5.3 18.0 22.7 6.2 45.4 14.1 8.2 26.5 27.6 15.1 7.6 7.1 4.1 16.5 26.8 33.7 29.4 16.3 13.3 7.0 2.7 19.1 9.7 7.6 22.2 4.8 16.6 29.2 28.0 7.9 5.8 2.9 11.4 17.8 11.3 44.4 11.3 19.7 6.6 4.2 8.9 9.5 19.6 9.0 6.0 3.9 4.0 40.0 56.7 1.7 9.0 11.7 9.2 31.7 8.9 23.9 5.6 1.6 4.8 1.4 2.2 21.7 3.3 1.3 4.1 10.8 13.1 10.2 26.0 11.0 7.3 54.0 3.6 9.4 10.4 19.4 22.8 5.5 9.3 15.8 6.8 26.9 5.8 3.0 11.5 54.4 0.4 6.3 8.0 18.5 35.4 33.5 8.2 6.9 8.0 11.3 3.2 11.6 11.3 7.1 3.5 28.1 21.0 3.9 46.9 10.4 9.1 6.7 2.1 4.9 1.6 0.8 18.7 5.7 5.8 1.1 23.3 14.1 5.2 0.6 1.5 1.4 6.6 7.5 19.2 31.0 27.2 20.7 18.0 22.7 26.5 27.6 26.8 22.2 28.0 44.4 48.5 60.9 30.2 46.0 10.5 6.4 56.8 5.6 19.9 3.6 27.7 14.1 8.2 31.5 18.3 16.5 0.0 16.1 12.9 127.4 9.8 26.5 1.7 82.0 29.6 24.5 60.1 24.8 20.9 19.5 25.7 24.9 40.2 157.0 8.2 27.6 35.3 82.7 21.8 3.3 78.3 60.0 4.1 29.2 27.8 7.6 18.3 38.4 5.4 66.5 44.8 65.1 1.0 223.2 222.5 35.4 56.4 39.9 8.7 148.2 27.7 5.1 4.3 5.3 32.9 7.5 17.4 3.1 12.8 44.4 9.8 129.2 37.7 15.2 85.9 254.2 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SFSWAP "SFRS8, SWAP" ENSG00000061936 "Splicing factor SWAP" Q12872 12 131711081-131799738 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Repressor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039362, HPA040063" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane, Cytosol" "HPA039362: AB_10794089, HPA040063: AB_10795413" "unprognostic (1.33e-2)" "unprognostic (2.53e-2)" "unprognostic (1.39e-3)" "unprognostic (2.04e-1)" "unprognostic (4.45e-2)" "unprognostic (2.39e-3)" "unprognostic (7.41e-3)" "unprognostic (2.31e-1)" "prognostic unfavorable (1.10e-4)" "unprognostic (3.44e-1)" "unprognostic (1.50e-2)" "unprognostic (3.30e-2)" "prognostic unfavorable (3.33e-8)" "unprognostic (7.50e-2)" "unprognostic (2.93e-2)" "unprognostic (3.48e-1)" "unprognostic (3.66e-2)" 26.9 18.3 18.5 10.1 20.8 28.1 26.3 18.5 24.8 27.1 13.7 25.9 10.1 24.6 4.0 23.2 24.5 4.8 20.2 18.2 19.0 24.9 19.4 20.3 11.3 20.4 19.3 29.0 21.9 7.4 21.7 8.1 19.8 21.8 4.3 9.3 20.2 6.8 29.5 32.6 24.6 5.6 16.9 28.4 20.8 16.3 21.2 12.6 24.5 6.7 7.6 22.3 24.3 25.1 26.1 23.0 16.0 17.0 12.6 10.3 35.8 19.7 13.6 22.9 15.6 22.6 12.3 31.9 18.0 14.8 11.9 23.9 22.7 18.1 13.2 9.9 36.0 29.0 12.9 27.0 13.4 37.8 27.4 11.7 20.4 20.8 24.9 18.2 14.3 24.3 40.9 12.3 10.4 32.7 31.9 57.1 41.9 14.0 38.0 36.7 16.2 25.2 13.3 18.8 25.1 28.3 18.7 15.6 25.1 12.5 22.5 29.1 18.6 19.0 24.8 14.8 22.3 35.0 41.2 31.7 18.7 25.5 25.9 2.0 4.1 1.9 3.0 2.7 3.0 2.1 2.8 2.6 2.9 3.7 3.0 3.4 5.6 5.4 3.4 7.2 2.4 1.8 18.5 20.8 18.5 24.8 18.2 19.0 20.4 19.3 19.8 16.9 21.2 25.1 46.4 73.7 44.5 48.6 37.9 38.9 41.5 19.0 42.1 49.7 25.4 25.9 19.3 21.5 38.6 14.7 66.7 30.4 52.6 22.1 0.0 23.1 21.4 27.0 48.8 39.3 21.6 38.7 55.1 26.6 31.8 39.2 37.8 39.7 38.0 47.1 21.4 16.7 22.1 42.1 43.2 24.9 14.2 27.4 21.4 12.9 30.1 30.3 23.2 36.5 35.4 33.7 50.4 58.3 85.1 28.6 24.1 29.7 43.6 44.7 20.8 11.8 30.7 62.4 46.0 52.1 38.1 39.5 42.8 39.7 46.9 43.6 45.9 48.4 22.9 48.2 SGCE DYT11 ENSG00000127990 "Sarcoglycan epsilon" O43556 7 94524204-94656572 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Disease variant, Dystonia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 116.6;Oligodendrocyte precursor cells: 133.2;Oligodendrocytes: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "gdT-cell: 2.1;memory B-cell: 4.4;naive B-cell: 6.6" "Group enriched" "Detected in many" 4 "B-cells: 6.6;T-cells: 2.1" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074790 Approved "Nucleoplasm,Golgi apparatus,Vesicles,Plasma membrane" Yes No 170000 "Cluster 19: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA074790: AB_2686713" "unprognostic (3.16e-3)" "unprognostic (9.06e-2)" "unprognostic (1.20e-1)" "unprognostic (1.20e-3)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.61e-5)" "unprognostic (1.19e-2)" "unprognostic (2.82e-2)" "unprognostic (6.93e-2)" "unprognostic (3.37e-1)" "unprognostic (6.80e-3)" "unprognostic (9.69e-2)" "unprognostic (5.71e-2)" "prognostic unfavorable (1.35e-4)" "unprognostic (1.43e-1)" "unprognostic (2.04e-1)" "unprognostic (2.44e-2)" 43.2 63.4 19.9 9.4 21.6 0.4 36.5 22.1 31.6 45.1 20.9 51.6 8.0 43.2 27.1 13.3 40.7 27.6 38.9 19.6 21.0 19.5 14.4 30.5 16.7 23.2 20.6 92.2 21.5 10.9 30.9 52.7 22.4 18.0 12.8 16.8 21.1 31.6 8.5 8.2 19.2 41.8 21.9 25.1 23.8 18.5 20.4 12.8 23.9 19.8 7.2 35.6 34.6 26.7 13.5 42.5 39.6 61.8 63.7 110.8 7.1 51.3 92.3 40.7 60.4 24.9 78.0 12.8 70.4 86.5 83.7 9.4 60.0 21.6 49.1 2.2 32.7 1.4 36.9 28.3 44.0 4.3 0.0 95.5 31.1 64.8 79.3 104.9 30.8 0.0 0.1 93.7 43.5 42.6 0.0 0.0 32.8 8.0 29.0 19.8 51.0 25.8 78.6 13.6 26.2 20.8 0.0 52.2 65.1 44.2 17.6 0.8 0.0 131.1 45.1 11.8 81.7 50.8 67.9 14.8 51.4 0.2 74.2 0.7 0.0 0.1 2.1 0.0 0.8 4.4 0.6 1.0 0.0 6.6 0.2 0.7 0.3 1.0 0.1 0.2 0.2 0.3 19.9 21.6 22.1 31.6 19.6 21.0 23.2 20.6 22.4 21.9 20.4 26.7 39.2 70.5 33.3 66.9 6.1 5.0 18.4 16.8 1.8 18.6 9.7 44.4 18.6 30.0 28.3 20.2 4.2 90.2 1.4 0.0 5.9 42.5 1.6 4.0 17.1 18.8 1.2 0.4 85.2 4.3 26.1 116.6 1.5 6.6 2.5 37.3 58.2 11.2 6.3 20.2 68.5 0.1 12.2 2.5 7.3 3.7 75.5 1.4 51.6 15.9 0.0 31.5 0.0 133.2 116.3 2.1 0.0 58.3 2.6 5.5 0.0 14.1 13.7 30.3 85.5 68.0 60.7 17.1 13.0 0.9 4.0 82.8 2.7 44.0 0.0 2.2 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SHANK1 "SPANK-1, SSTRIP, synamon" ENSG00000161681 "SH3 and multiple ankyrin repeat domains 1" Q9Y566 19 50659255-50719802 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 71.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.7;Excitatory neurons: 29.6;Horizontal cells: 8.4;Inhibitory neurons: 32.9;Oligodendrocyte precursor cells: 7.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 28.8;cerebral cortex: 71.1;hippocampal formation: 36.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 5.2;THP-1: 2.4;U-138 MG: 2.7;U-2 OS: 7.3;U-87 MG: 2.9;U-937: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032129, HPA032130" Uncertain Supported "Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032129: AB_10602796, HPA032130: AB_2674169" "unprognostic (1.62e-1)" "unprognostic (4.40e-2)" "unprognostic (7.83e-3)" "unprognostic (4.62e-2)" "unprognostic (1.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.35e-2)" "unprognostic (5.02e-2)" "unprognostic (1.61e-1)" "unprognostic (7.51e-2)" "unprognostic (3.27e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-2)" "unprognostic (5.14e-2)" "unprognostic (4.66e-3)" "unprognostic (1.29e-3)" 0.0 1.2 20.6 0.0 28.8 0.3 0.1 1.5 71.1 0.5 0.0 0.1 0.0 0.4 0.1 0.0 2.4 0.2 0.1 36.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.6 1.1 0.1 0.0 0.1 0.0 5.3 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.5 7.5 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.8 0.0 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.5 0.1 0.1 0.5 0.8 0.0 0.0 5.2 0.0 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 2.4 1.6 2.7 7.3 0.0 0.0 0.0 0.0 0.0 2.9 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.8 1.5 71.1 36.8 0.0 0.0 0.2 0.0 0.0 7.5 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 4.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 29.6 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.4 32.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.1 0.0 7.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SHANK2 "CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3" ENSG00000162105 "SH3 and multiple ankyrin repeat domains 2" Q9UPX8 11 70467854-71252577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 31.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 153.5;Horizontal cells: 136.3;Inhibitory neurons: 167.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 8 "amygdala: 7.7;basal ganglia: 7.5;cerebral cortex: 9.3;hippocampal formation: 9.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 11.5;Karpas-707: 17.5;RT4: 15.9;T-47d: 16.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008174, HPA017220" Approved Approved "Nuclear speckles,Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Nuclear speckles" "HPA008174: AB_1856822, HPA017220: " "unprognostic (3.08e-1)" "unprognostic (1.31e-3)" "unprognostic (1.79e-1)" "unprognostic (1.51e-2)" "unprognostic (1.51e-1)" "unprognostic (7.23e-5)" "unprognostic (1.24e-1)" "unprognostic (6.67e-2)" "unprognostic (1.83e-2)" "unprognostic (8.42e-2)" "unprognostic (4.87e-2)" "unprognostic (4.01e-1)" "prognostic favorable (1.94e-6)" "unprognostic (3.46e-2)" "unprognostic (2.34e-1)" "unprognostic (4.03e-2)" "unprognostic (4.80e-2)" 1.3 1.2 7.7 0.5 7.5 0.0 4.5 0.2 9.3 1.3 31.7 2.4 1.5 1.0 2.2 3.4 5.1 0.8 0.0 9.5 0.0 4.9 3.8 3.7 0.1 0.0 0.0 0.1 7.5 0.1 2.2 1.9 0.0 3.2 2.0 5.5 9.8 1.8 0.0 0.9 1.3 0.4 0.0 1.1 3.0 0.9 1.0 0.0 6.0 0.0 0.4 1.1 0.3 0.9 0.5 7.4 4.1 0.0 0.6 0.4 4.5 0.7 0.3 0.0 0.0 6.6 3.1 6.2 2.2 0.0 0.1 1.1 0.0 4.8 0.0 0.0 0.2 0.0 0.0 11.5 0.0 0.0 1.9 0.1 1.8 0.0 0.0 1.6 0.0 0.1 0.0 17.5 1.7 10.5 0.0 0.1 3.5 10.2 0.3 0.0 9.9 8.2 5.2 15.9 3.5 1.1 0.0 8.4 0.0 5.2 16.4 0.0 0.0 0.0 1.5 0.1 0.0 0.1 0.6 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 7.5 0.2 9.3 9.5 0.0 0.0 0.0 0.0 0.0 1.0 0.9 8.0 41.7 17.0 21.5 0.2 0.0 3.2 3.2 0.6 17.9 26.9 13.0 3.7 11.5 5.4 7.3 0.0 12.8 0.4 3.2 3.9 8.4 1.7 30.0 3.2 1.3 0.0 0.0 153.5 2.2 2.9 1.8 10.2 13.0 2.5 1.2 0.4 21.9 1.2 136.3 167.5 7.9 8.2 0.0 0.3 2.1 0.0 0.4 5.4 14.0 0.0 4.6 0.0 41.7 5.3 10.7 2.7 0.7 0.4 10.9 0.6 10.8 23.3 1.0 0.0 0.3 1.3 0.7 0.9 1.3 0.6 14.6 0.3 0.1 5.5 4.0 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHARPIN "DKFZP434N1923, SIPL1" ENSG00000179526 "SHANK associated RH domain interactor" Q9H0F6 8 144098633-144108124 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 4 "Early spermatids: 391.4;Late spermatids: 1255.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024825, HPA044453" Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Golgi apparatus, Cytosol" "HPA024825: , HPA044453: AB_10962490" "unprognostic (4.91e-2)" "unprognostic (3.47e-2)" "unprognostic (1.35e-2)" "unprognostic (7.88e-2)" "unprognostic (3.32e-2)" "unprognostic (9.54e-2)" "unprognostic (1.31e-3)" "unprognostic (6.58e-2)" "unprognostic (1.74e-1)" "unprognostic (4.13e-3)" "unprognostic (5.44e-2)" "unprognostic (7.91e-2)" "unprognostic (1.84e-3)" "unprognostic (2.87e-2)" "unprognostic (1.55e-1)" "unprognostic (2.24e-1)" "unprognostic (1.00e-1)" 29.9 39.2 38.5 16.5 39.9 32.6 27.2 39.1 52.2 29.9 35.7 37.7 20.7 29.4 11.2 29.9 28.8 19.4 44.4 36.0 39.2 36.7 39.1 27.1 21.8 41.7 39.7 27.4 35.1 28.7 26.7 17.2 39.9 33.8 12.7 8.9 33.8 22.2 49.4 27.1 26.3 17.3 37.7 33.4 34.2 94.7 39.8 19.6 29.1 39.7 13.9 31.2 26.4 38.7 26.9 43.5 20.4 17.9 34.2 35.1 22.5 23.5 29.5 34.0 32.9 24.9 42.0 12.0 38.5 30.6 17.1 28.4 10.8 42.2 8.2 33.0 23.3 31.4 40.1 29.9 61.6 11.6 23.1 40.4 59.4 28.3 30.8 37.6 36.8 36.6 18.2 27.3 30.2 43.8 35.2 26.6 9.3 53.6 124.2 23.6 16.7 39.4 35.2 28.3 20.3 30.7 45.0 62.1 41.5 14.3 69.4 35.8 34.0 26.5 38.9 32.5 32.4 30.0 25.4 16.3 38.3 25.9 23.5 22.6 33.5 53.5 29.9 41.2 32.4 23.3 28.5 38.3 30.0 21.8 23.5 24.7 17.5 33.9 34.8 42.7 34.1 22.4 38.5 39.9 39.1 52.2 36.0 39.2 41.7 39.7 39.9 37.7 39.8 38.7 56.3 9.6 18.1 10.4 39.4 24.0 32.9 37.0 26.2 27.1 43.5 44.4 20.9 31.5 26.1 35.0 4.2 56.7 44.4 87.2 119.3 53.8 391.4 28.3 26.8 38.9 35.4 88.0 8.0 49.5 52.6 35.9 52.0 24.4 13.3 35.1 36.4 37.2 59.0 48.8 9.5 45.6 44.7 42.1 32.9 1255.3 49.0 33.0 46.2 15.0 57.7 45.4 59.8 9.0 14.3 95.2 81.3 43.6 31.2 36.1 83.1 86.4 20.6 28.9 52.6 26.8 44.2 181.7 67.9 33.5 32.4 43.1 38.8 37.4 59.0 33.9 SHISA6 FLJ45455 ENSG00000188803 "Shisa family member 6" Q6ZSJ9 17 11241213-11564063 "Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 46.2;cervix: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.3;Excitatory neurons: 27.4;Inhibitory neurons: 181.4;Oligodendrocyte precursor cells: 77.4;Peritubular cells: 29.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "OE19: 52.0" "Low region specificity" "Detected in all" HPA023440 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA023440: AB_1848945" "unprognostic (1.70e-1)" "unprognostic (2.78e-2)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "prognostic unfavorable (8.41e-4)" "unprognostic (3.11e-2)" "unprognostic (1.71e-1)" "unprognostic (8.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (9.63e-2)" "unprognostic (1.27e-1)" "unprognostic (2.40e-4)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.20e-2)" "unprognostic (2.47e-2)" 1.7 0.6 17.7 0.0 11.0 0.0 1.1 23.2 25.3 16.8 0.8 0.6 0.2 6.2 0.7 0.8 1.8 0.3 0.8 46.2 18.9 1.9 0.0 0.2 0.0 43.3 25.5 0.6 1.0 3.4 0.2 0.1 24.4 4.3 0.4 1.1 0.2 7.3 0.7 0.8 0.3 0.5 44.8 0.0 4.2 2.9 34.7 0.0 0.5 1.3 0.0 1.1 3.4 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 52.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 11.0 23.2 25.3 46.2 18.9 43.3 25.5 24.4 44.8 34.7 27.0 0.9 0.0 0.0 50.3 0.0 0.1 0.1 0.0 1.2 4.0 1.8 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.5 16.9 1.6 1.2 0.0 27.4 0.0 0.0 2.1 0.0 0.5 0.0 5.6 0.4 0.0 0.1 0.0 181.4 0.0 0.0 0.0 0.3 15.2 5.0 0.0 1.8 12.2 0.0 0.8 0.0 77.4 2.4 0.0 0.0 29.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.2 1.7 0.4 2.5 0.1 0.1 0.0 0.1 4.4 0.2 0.2 SHKBP1 "PP203, Sb1" ENSG00000160410 "SH3KBP1 binding protein 1" Q8TBC3 19 40576853-40591399 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 127.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041887 Uncertain Approved "Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Cell Junctions" "HPA041887: AB_10794639" "unprognostic (1.26e-1)" "unprognostic (7.55e-2)" "unprognostic (1.38e-1)" "unprognostic (4.52e-2)" "unprognostic (8.24e-2)" "unprognostic (9.14e-2)" "unprognostic (1.66e-3)" "unprognostic (3.53e-2)" "unprognostic (6.98e-2)" "unprognostic (6.69e-3)" "unprognostic (1.42e-1)" "unprognostic (6.87e-2)" "unprognostic (5.29e-2)" "unprognostic (6.15e-2)" "unprognostic (2.67e-1)" "unprognostic (1.65e-1)" "unprognostic (8.64e-2)" 33.7 32.1 14.6 39.4 16.5 66.8 29.1 15.3 19.4 35.3 15.4 34.9 18.4 34.4 7.7 47.0 33.3 14.4 29.6 14.8 16.1 42.3 30.0 52.3 40.9 19.7 16.6 25.2 37.6 15.8 21.8 14.3 17.2 35.1 10.4 1.3 31.7 13.5 15.8 32.6 45.5 15.8 15.6 127.1 41.2 17.2 19.4 29.5 35.0 6.8 25.0 36.5 35.6 20.0 70.9 107.1 21.1 30.2 18.0 20.0 39.7 26.8 39.9 41.1 56.2 46.9 47.5 73.9 52.1 42.3 35.0 30.2 27.3 50.8 19.4 114.6 65.1 53.9 29.4 32.1 38.8 50.6 147.9 32.4 36.2 37.4 23.3 30.0 60.8 81.7 30.7 60.2 32.0 61.6 52.1 70.5 15.3 63.5 39.2 92.9 27.4 55.7 34.0 57.0 17.4 40.2 41.4 22.3 25.1 20.2 35.5 82.7 46.4 41.2 54.0 65.1 54.1 56.4 28.4 50.6 66.2 59.5 37.4 223.9 217.9 216.7 74.2 202.2 60.1 77.5 71.4 76.5 157.3 69.0 41.1 48.2 453.9 72.3 246.4 46.4 109.8 213.1 14.6 16.5 15.3 19.4 14.8 16.1 19.7 16.6 17.2 15.6 19.4 20.0 28.8 12.8 19.9 1.3 53.1 8.5 20.5 41.7 10.2 2.1 9.5 7.2 4.3 17.2 30.8 29.5 6.2 24.5 40.8 35.2 29.4 42.5 8.6 5.4 9.3 25.0 22.8 25.0 2.1 38.6 53.1 13.5 37.2 13.3 51.5 18.2 26.7 13.2 76.5 3.3 1.8 17.9 48.8 82.0 36.3 18.4 14.6 66.8 23.2 3.7 93.3 6.3 56.7 1.5 6.4 39.0 35.9 12.4 33.9 11.5 28.1 31.7 14.2 1.8 0.0 7.0 15.2 3.5 26.8 19.3 9.8 29.6 45.0 14.4 22.0 20.7 SHROOM2 APXL ENSG00000146950 "Shroom family member 2" Q13796 X 9786429-9949443 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 20.8" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Cone photoreceptor cells: 47.9;Microglial cells: 24.4;Peritubular cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RT4: 19.2;SK-MEL-30: 18.2;SuSa: 18.6;WM-115: 23.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA051646 Approved Approved "Plasma membrane,Cell Junctions,Cytosol" No No "Cluster 77: Retina - Visual perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cell Junctions" Cytosol "HPA051646: AB_2681562" "unprognostic (8.65e-3)" "unprognostic (1.36e-3)" "unprognostic (4.68e-2)" "unprognostic (4.06e-2)" "unprognostic (6.99e-3)" "unprognostic (8.05e-2)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (2.51e-1)" "unprognostic (6.54e-2)" "unprognostic (2.82e-2)" "unprognostic (9.73e-2)" "prognostic favorable (1.35e-7)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (1.93e-1)" "unprognostic (7.67e-3)" 0.7 1.8 4.3 0.4 6.0 0.0 1.0 3.6 10.1 2.4 5.4 1.5 0.7 1.5 2.7 5.0 1.6 3.1 0.7 5.9 4.0 3.7 4.0 4.1 0.3 4.8 5.0 6.9 3.7 2.4 4.4 7.6 4.3 5.3 1.3 20.8 3.2 2.6 0.1 4.1 0.5 0.8 4.3 0.7 1.5 3.4 4.7 3.6 1.4 0.1 1.3 2.4 3.1 5.2 6.2 0.7 11.0 1.5 0.6 1.7 6.2 0.6 2.0 2.4 3.8 7.5 0.1 0.0 2.0 1.6 0.4 4.8 5.7 15.9 2.8 0.0 4.3 0.0 0.0 1.2 3.5 0.0 7.4 0.3 10.9 18.0 0.7 3.9 13.7 0.0 0.0 0.0 3.9 6.5 0.0 0.1 9.7 0.0 0.0 0.0 12.1 0.0 10.2 19.2 1.6 0.9 0.5 0.1 18.2 18.6 6.5 0.4 6.4 17.3 2.2 0.1 0.6 0.0 0.0 0.0 11.4 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 6.0 3.6 10.1 5.9 4.0 4.8 5.0 4.3 4.3 4.7 5.2 1.1 0.0 1.5 26.4 0.0 1.9 3.3 2.8 10.8 9.5 3.4 1.7 4.1 4.3 3.1 3.7 47.9 8.9 0.0 2.0 3.9 3.0 0.5 4.8 2.5 7.2 1.2 2.7 9.5 0.0 1.3 1.5 3.1 5.9 0.0 5.4 10.0 5.7 0.7 1.7 9.5 0.3 4.1 0.8 0.0 1.0 3.7 0.2 0.0 24.4 0.0 2.4 0.0 9.5 4.6 1.6 0.1 83.1 0.0 5.4 0.1 1.0 2.8 18.0 0.0 0.6 1.8 0.1 1.1 10.8 2.0 2.1 0.5 5.5 0.9 5.3 SHTN1 "KIAA1598, shootin-1, shootin1" ENSG00000187164 "Shootin 1" A0MZ66 10 116881477-117126586 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 128.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 31 "classical monocyte: 19.7;intermediate monocyte: 12.9;myeloid DC: 19.3;non-classical monocyte: 6.6;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 42 "dendritic cells: 19.3;monocytes: 19.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037942, HPA037943" Enhanced Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA037942: AB_2675748, HPA037943: AB_10671637" "unprognostic (1.00e-1)" "unprognostic (2.50e-2)" "unprognostic (6.77e-3)" "unprognostic (2.81e-1)" "unprognostic (7.85e-2)" "unprognostic (1.61e-1)" "unprognostic (2.42e-2)" "unprognostic (1.03e-1)" "unprognostic (2.56e-1)" "unprognostic (1.35e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (5.07e-4)" "unprognostic (2.17e-2)" "unprognostic (1.48e-1)" "unprognostic (2.47e-1)" "unprognostic (1.85e-1)" "prognostic unfavorable (5.08e-6)" 1.9 4.0 63.2 4.5 94.5 0.7 4.9 42.7 54.1 2.9 10.0 4.3 4.1 2.4 4.6 3.1 2.9 3.8 1.6 46.9 73.9 4.7 7.6 6.2 2.9 77.5 70.1 3.9 12.2 8.0 6.2 3.1 69.5 4.2 5.2 10.6 6.7 1.4 0.3 5.6 4.8 2.0 48.6 4.5 5.7 6.4 79.5 2.7 7.5 0.8 2.3 2.1 2.1 128.1 24.2 13.4 1.3 2.8 0.0 0.0 12.8 2.0 5.3 4.0 7.6 15.1 15.5 0.0 4.0 7.4 11.8 12.2 10.6 8.9 4.1 0.0 11.0 0.0 14.5 8.9 1.7 4.3 3.7 0.5 7.5 4.0 7.5 10.3 9.7 6.4 6.7 0.1 2.8 9.6 0.0 0.1 5.0 4.8 8.9 0.0 17.5 5.4 10.3 3.3 14.5 5.7 16.0 23.3 13.8 15.7 18.4 3.8 17.0 1.4 9.4 0.1 11.7 2.4 0.1 0.0 7.1 0.0 7.2 0.0 19.7 0.2 0.0 12.9 0.0 0.0 0.1 0.0 19.3 0.0 0.1 0.0 0.4 0.0 6.6 12.9 0.4 5.6 63.2 94.5 42.7 54.1 46.9 73.9 77.5 70.1 69.5 48.6 79.5 128.1 1.4 76.9 35.7 0.0 2.0 0.0 18.9 0.0 15.4 92.3 31.8 15.9 4.9 35.8 23.5 23.9 62.6 42.1 24.7 10.6 21.5 46.4 7.5 43.4 10.6 5.1 17.0 1.7 0.0 53.2 30.9 11.2 36.7 81.1 2.5 23.6 1.8 50.5 37.3 48.8 0.0 15.5 0.0 83.6 0.0 11.7 11.1 77.2 0.0 0.0 90.3 13.8 1.0 0.0 0.0 46.2 42.5 5.3 0.8 25.2 21.2 58.4 18.2 59.4 13.1 18.2 5.0 22.0 39.6 20.5 0.0 20.0 3.1 28.4 15.7 15.4 SIGLEC10 "MGC126774, PRO940, SIGLEC-10, SLG2" ENSG00000142512 "Sialic acid binding Ig like lectin 10" Q96LC7 19 51410020-51417803 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 38.5" "Cell type enhanced" "Detected in some" "B-cells: 33.0;granulocytes: 39.3;Kupffer cells: 93.9;Macrophages: 51.5" "Cancer enhanced" "Detected in all" "glioma: 11.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "eosinophil: 765.3;intermediate monocyte: 252.0;non-classical monocyte: 539.2" "Group enriched" "Detected in many" 16 "granulocytes: 765.3;monocytes: 539.2" "Cell line enhanced" "Detected in some" "Daudi: 28.8;HDLM-2: 9.0;HEL: 14.9;HMC-1: 10.7;NB-4: 10.4;U-698: 21.3;U-937: 12.0" "Not detected" "Not detected" "CAB025807, HPA027093" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" "Intracellular and membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Cytosol "Plasma membrane, Actin filaments" "CAB025807: , HPA027093: AB_1856858" "unprognostic (7.18e-2)" "unprognostic (3.90e-3)" "unprognostic (1.11e-2)" "unprognostic (3.67e-2)" "unprognostic (3.95e-2)" "unprognostic (9.41e-2)" "unprognostic (8.18e-2)" "unprognostic (2.11e-1)" "unprognostic (3.16e-2)" "unprognostic (1.83e-1)" "unprognostic (1.63e-1)" "unprognostic (3.12e-1)" "prognostic unfavorable (4.74e-5)" "unprognostic (2.73e-1)" "unprognostic (1.69e-2)" "unprognostic (1.39e-1)" "unprognostic (9.05e-2)" 3.5 6.4 3.9 33.9 4.8 14.9 2.1 4.3 6.0 2.1 3.5 5.4 7.0 2.1 1.0 2.0 2.4 3.7 1.4 3.9 6.2 1.7 3.2 8.5 19.9 11.4 6.9 1.6 3.5 1.0 1.4 1.8 8.8 3.0 4.6 1.1 2.2 1.1 0.7 1.2 12.2 4.5 6.3 38.5 4.7 1.3 6.3 4.0 1.0 1.1 19.5 5.5 1.2 9.4 0.2 0.0 0.5 0.5 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.1 1.3 28.8 0.9 0.1 0.3 0.5 0.0 0.2 0.0 9.0 2.5 14.9 0.3 0.1 0.0 6.4 10.7 0.1 0.0 0.1 0.0 0.1 0.0 1.7 0.7 1.4 0.0 0.6 0.2 10.4 0.8 0.7 0.4 1.9 0.1 0.5 0.0 0.3 0.4 0.4 0.3 0.1 0.2 0.5 0.1 5.2 0.7 0.7 1.3 0.6 0.2 1.3 0.3 21.3 0.5 12.0 0.5 14.0 41.9 765.3 0.8 252.0 0.4 41.4 0.5 0.5 38.0 27.4 0.3 0.5 87.2 0.4 539.2 2.2 1.1 40.7 3.9 4.8 4.3 6.0 3.9 6.2 11.4 6.9 8.8 6.3 6.3 9.4 0.7 3.2 1.3 0.3 33.0 0.1 1.2 0.0 0.0 1.4 0.4 0.9 0.3 0.0 0.0 1.8 2.1 0.1 0.6 0.1 0.0 0.0 0.9 0.0 0.0 4.2 0.0 5.2 0.6 0.0 0.1 0.8 0.0 0.1 39.3 0.1 0.4 1.0 8.1 0.0 0.2 0.1 0.0 93.9 6.3 0.4 0.0 51.5 0.0 15.0 14.8 0.2 6.2 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.1 0.0 0.7 0.0 2.0 0.4 0.5 0.7 0.0 1.3 0.1 2.7 0.1 0.0 0.9 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIN3B KIAA0700 ENSG00000127511 "SIN3 transcription regulator family member B" O75182 19 16829398-16880353 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050329 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA050329: AB_2681089" "unprognostic (2.71e-3)" "unprognostic (8.89e-2)" "unprognostic (1.32e-3)" "unprognostic (6.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.05e-2)" "unprognostic (5.44e-2)" "unprognostic (9.89e-2)" "unprognostic (5.42e-3)" "unprognostic (2.77e-1)" "prognostic favorable (4.37e-4)" "prognostic unfavorable (3.58e-4)" "unprognostic (1.18e-3)" "unprognostic (8.45e-2)" "unprognostic (1.49e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" 38.6 31.7 30.1 21.7 28.4 12.6 42.0 8.6 33.3 57.2 12.7 35.9 15.0 59.3 24.1 25.9 49.9 20.4 27.3 30.1 22.7 31.6 19.8 43.6 26.8 19.8 21.8 58.0 25.5 37.8 32.3 29.0 27.0 43.9 12.3 10.0 30.9 35.2 24.7 32.9 36.4 30.6 10.3 43.0 27.2 51.7 24.8 13.2 42.8 14.9 18.1 34.0 43.7 24.5 28.1 14.7 24.4 31.5 19.7 18.1 76.8 23.3 19.2 31.6 27.9 36.4 25.7 25.0 25.5 27.2 26.7 23.6 20.4 20.9 29.1 26.2 36.8 27.0 35.6 16.7 25.9 15.8 20.8 29.9 26.9 21.3 18.2 25.1 29.1 19.7 22.2 15.0 22.4 33.7 21.7 25.5 30.4 14.6 46.6 28.4 22.4 16.6 18.0 23.5 18.0 22.5 29.6 22.5 18.4 32.5 15.9 14.7 38.6 30.5 18.5 44.6 26.5 21.3 16.8 25.0 21.1 20.6 23.1 0.1 4.2 3.9 1.0 3.8 0.6 3.5 0.9 1.1 1.3 2.7 1.1 0.8 2.0 1.2 3.4 1.5 0.3 1.5 30.1 28.4 8.6 33.3 30.1 22.7 19.8 21.8 27.0 10.3 24.8 24.5 45.4 22.4 11.9 30.7 18.9 7.9 11.6 7.4 14.2 20.3 14.4 18.4 8.3 1.5 8.6 3.7 14.6 21.9 9.5 7.0 3.9 10.6 11.4 16.3 34.6 18.8 4.9 6.9 29.9 8.6 29.2 16.0 13.7 36.2 5.1 29.9 10.8 7.0 17.6 10.1 29.8 8.4 0.0 14.6 5.5 24.2 50.7 13.9 5.4 19.7 14.6 8.0 10.3 21.6 26.3 14.5 4.0 66.5 22.0 14.2 4.2 7.5 6.9 14.5 6.6 17.5 13.7 9.7 9.2 14.4 8.1 124.9 11.7 34.5 7.3 17.9 SIPA1 SPA1 ENSG00000213445 "Signal-induced proliferation-associated 1" Q96FS4 11 65638101-65650918 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 95.6" "Cell type enhanced" "Detected in many" "dendritic cells: 82.5;NK-cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020833, HPA039867" Enhanced Approved "Nucleoplasm,Nucleoli,Golgi apparatus,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoli "Nucleoplasm, Golgi apparatus, Plasma membrane" "CAB020833: , HPA039867: AB_2676716" "unprognostic (6.10e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (9.42e-4)" "unprognostic (1.35e-2)" "unprognostic (2.93e-1)" "unprognostic (2.32e-2)" "unprognostic (3.35e-2)" "unprognostic (1.09e-1)" "unprognostic (3.30e-2)" "unprognostic (6.44e-2)" "unprognostic (5.85e-2)" "unprognostic (4.86e-2)" "prognostic unfavorable (3.52e-6)" "unprognostic (1.60e-1)" "unprognostic (2.78e-2)" "unprognostic (1.14e-2)" "unprognostic (1.49e-1)" 21.6 17.2 16.4 48.7 15.5 53.8 16.2 14.1 16.8 20.6 10.3 24.0 12.5 20.9 3.4 14.3 19.5 16.0 25.7 15.8 13.2 17.0 15.0 37.0 60.7 22.3 16.0 13.1 8.4 3.5 7.5 19.4 19.5 17.1 6.0 0.9 14.1 10.0 10.0 8.1 37.8 12.0 19.5 95.6 15.9 4.7 24.5 21.3 14.9 6.4 32.5 18.8 15.3 21.0 1.6 13.3 9.1 20.1 5.4 11.1 21.7 14.9 12.7 11.7 11.3 3.9 14.5 21.3 33.2 7.6 0.4 7.8 3.4 5.1 3.9 22.7 8.1 52.6 20.7 7.4 9.6 21.5 21.5 11.4 2.3 16.2 2.1 11.5 34.4 21.8 30.3 9.2 5.8 5.8 8.6 36.1 6.4 5.4 12.3 38.8 5.1 19.3 4.4 0.8 3.4 20.9 7.5 12.6 31.7 8.5 9.6 32.5 49.2 14.2 28.7 15.2 3.0 14.1 12.2 48.4 19.5 33.0 42.0 3.2 3.3 9.3 5.8 3.9 4.1 4.1 2.8 3.7 2.3 4.7 2.0 3.1 11.1 4.7 4.8 2.1 3.0 3.0 16.4 15.5 14.1 16.8 15.8 13.2 22.3 16.0 19.5 19.5 24.5 21.0 22.5 6.4 5.2 7.5 59.0 6.8 24.7 23.2 17.6 2.1 24.8 26.5 7.2 21.5 19.2 23.9 0.0 10.1 82.5 16.5 37.2 19.8 3.0 8.3 6.8 26.8 21.0 31.6 0.1 14.5 19.6 12.2 11.2 14.9 7.0 37.1 42.8 22.0 38.4 5.0 0.2 12.8 30.5 44.4 11.4 9.8 8.1 40.2 10.6 14.0 23.7 7.6 88.6 0.5 4.0 27.2 12.7 13.2 29.6 29.0 39.0 20.7 6.0 1.8 13.1 7.4 20.9 0.8 13.8 14.4 11.1 13.5 50.4 30.9 14.3 31.9 SIPA1L1 "E6TP1, KIAA0440, SPAR1" ENSG00000197555 "Signal induced proliferation associated 1 like 1" O43166 14 71320449-71741229 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 575.1;Inhibitory neurons: 447.6;Oligodendrocyte precursor cells: 221.2;Oligodendrocytes: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 22.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 101.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002875, HPA077689" Approved Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments" "HPA002875: AB_1079974, HPA077689: " "unprognostic (1.50e-3)" "unprognostic (2.99e-1)" "unprognostic (3.34e-2)" "unprognostic (5.64e-3)" "unprognostic (4.19e-2)" "unprognostic (4.14e-1)" "unprognostic (7.89e-2)" "unprognostic (4.86e-2)" "unprognostic (3.09e-1)" "unprognostic (8.62e-2)" "unprognostic (2.61e-1)" "unprognostic (5.27e-2)" "prognostic favorable (6.80e-8)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (7.03e-2)" 6.2 14.5 29.7 11.6 33.4 11.7 9.0 6.1 27.8 9.4 31.3 12.1 10.3 7.1 11.0 14.4 13.8 15.5 3.3 30.9 4.5 14.9 12.3 11.5 11.0 2.7 0.5 4.7 12.7 19.2 16.0 5.1 1.4 7.9 11.7 13.3 10.7 8.5 3.0 8.7 11.1 10.5 0.6 25.3 18.1 19.8 10.1 12.5 14.3 2.8 15.8 12.7 6.1 11.3 27.0 8.3 18.9 14.2 5.6 16.0 34.2 35.9 42.4 14.3 18.1 48.1 14.8 12.6 9.1 59.1 12.9 26.1 13.9 32.3 27.1 11.4 6.5 26.5 55.3 11.3 46.3 3.2 9.8 11.7 26.7 22.1 52.0 16.3 15.5 17.5 11.8 30.7 19.8 40.5 10.8 3.0 10.8 24.6 22.4 15.7 20.4 13.4 10.2 41.1 23.2 61.9 36.8 28.6 2.6 12.1 17.0 1.4 43.3 101.4 37.2 11.6 20.8 25.0 30.3 18.3 17.3 8.6 34.6 6.9 5.2 1.1 1.7 5.8 3.8 3.2 1.5 2.4 1.3 7.4 1.0 1.1 22.9 2.2 7.1 0.4 1.6 2.3 29.7 33.4 6.1 27.8 30.9 4.5 2.7 0.5 1.4 0.6 10.1 11.3 14.4 67.3 30.5 163.9 53.8 11.9 15.2 20.2 30.7 19.6 13.0 21.2 5.3 21.5 23.6 14.7 18.8 7.8 23.9 19.3 13.7 24.6 74.4 28.8 18.8 12.9 32.4 1.3 575.1 19.9 8.5 11.3 46.9 35.3 13.9 26.4 5.0 17.5 5.1 58.9 447.6 16.8 10.2 21.4 67.2 31.2 7.8 49.2 5.4 120.9 34.6 58.2 9.2 221.2 251.3 23.0 15.5 35.3 24.9 16.2 18.3 28.4 34.4 15.9 0.0 5.4 18.2 22.4 36.8 17.3 8.4 9.4 24.3 102.0 22.5 27.2 SIPA1L3 "KIAA0545, SPAR3" ENSG00000105738 "Signal induced proliferation associated 1 like 3" O60292 19 37907208-38208369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 28.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 93.7;Inhibitory neurons: 87.3;Oligodendrocyte precursor cells: 99.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 59.6" "Low region specificity" "Detected in all" "HPA042072, HPA045480, HPA074988" Uncertain Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nucleoplasm, Golgi apparatus" "HPA042072: AB_2677832, HPA045480: AB_2679342, HPA074988: " "unprognostic (4.24e-2)" "unprognostic (1.23e-1)" "unprognostic (1.86e-1)" "unprognostic (5.56e-2)" "unprognostic (9.99e-2)" "unprognostic (1.22e-2)" "unprognostic (1.31e-2)" "unprognostic (5.48e-2)" "unprognostic (3.11e-1)" "unprognostic (6.05e-2)" "unprognostic (3.15e-1)" "unprognostic (5.43e-2)" "unprognostic (9.26e-3)" "unprognostic (6.45e-2)" "unprognostic (4.94e-2)" "unprognostic (5.36e-2)" "unprognostic (1.96e-2)" 2.2 3.0 6.0 6.6 3.0 2.9 5.1 10.4 16.2 4.8 2.6 10.6 18.4 3.3 1.3 4.9 4.8 3.9 6.2 28.9 2.0 6.4 3.4 5.7 6.8 4.2 4.1 2.9 9.7 3.3 3.2 1.4 3.5 5.3 7.0 5.0 8.4 3.5 6.5 11.1 18.1 1.8 1.6 7.3 9.1 4.3 5.6 3.8 10.0 7.3 5.5 4.3 3.6 5.5 34.4 59.6 7.3 9.3 4.3 4.3 4.9 14.5 12.2 9.4 8.8 20.6 19.5 19.5 12.2 12.4 7.9 7.6 6.7 27.1 10.4 6.7 3.3 5.3 5.5 6.5 8.3 3.7 5.5 3.3 14.1 17.5 37.3 13.9 10.8 5.6 3.9 4.1 16.6 10.6 5.0 5.1 6.0 27.2 15.8 10.8 5.9 2.9 20.7 29.1 17.3 9.3 16.0 27.1 2.2 3.9 18.0 3.5 23.2 15.6 5.5 48.4 22.6 5.4 10.0 6.6 20.1 4.9 20.6 0.1 0.1 0.4 0.1 0.2 0.0 1.1 0.1 0.2 0.1 1.5 0.1 0.5 0.1 0.3 1.5 0.3 0.1 0.1 6.0 3.0 10.4 16.2 28.9 2.0 4.2 4.1 3.5 1.6 5.6 5.5 4.8 6.4 10.1 41.4 24.5 12.0 5.2 10.4 6.2 21.9 22.6 12.1 5.2 22.8 10.8 23.9 14.6 2.1 9.3 93.7 3.9 7.2 4.5 19.8 4.8 5.4 25.2 10.8 61.1 15.3 1.4 3.7 40.2 16.5 2.5 4.8 6.4 23.5 3.5 33.7 87.3 46.3 20.3 5.1 13.9 9.2 2.1 8.3 5.4 50.6 7.1 3.0 5.2 99.5 58.7 13.4 38.7 1.9 12.8 6.6 50.0 21.1 19.1 5.7 6.6 4.5 3.6 1.7 5.1 8.9 16.1 0.8 5.1 1.7 30.4 5.6 SKAP1 "SCAP1, SKAP55" ENSG00000141293 "Src kinase associated phosphoprotein 1" Q86WV1 17 48133442-48430275 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.8" "Cell type enhanced" "Detected in many" "dendritic cells: 107.1;granulocytes: 120.1;Late spermatids: 156.1;NK-cells: 213.1;T-cells: 147.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "CAPAN-2: 29.3;HDLM-2: 16.0;HMC-1: 13.0;JURKAT: 22.2;Karpas-707: 15.7;RPMI-8226: 19.8;RPTEC TERT1: 22.6;U-266/70: 14.8;U-266/84: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA002969, CAB025882, CAB055513" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" Cytosol "CAB025882: , CAB055513: , HPA002969: AB_1079870" "prognostic favorable (5.07e-4)" "unprognostic (1.10e-2)" "unprognostic (2.19e-2)" "unprognostic (1.80e-2)" "unprognostic (2.28e-2)" "unprognostic (1.43e-2)" "unprognostic (2.61e-2)" "unprognostic (1.57e-2)" "unprognostic (8.39e-2)" "unprognostic (1.81e-1)" "unprognostic (3.38e-1)" "unprognostic (1.71e-1)" "unprognostic (5.71e-2)" "unprognostic (6.20e-2)" "unprognostic (2.72e-1)" "unprognostic (1.94e-1)" "prognostic favorable (3.14e-4)" 1.4 6.4 0.1 11.2 0.2 6.5 8.3 0.0 0.2 10.1 0.0 3.4 2.7 3.8 17.2 1.7 13.7 3.6 0.5 0.3 0.5 11.9 3.1 5.4 28.7 0.9 0.2 0.8 5.4 13.8 9.8 0.5 0.4 1.0 4.6 0.0 6.1 6.2 0.2 0.8 5.3 1.1 1.4 12.2 4.9 9.5 0.2 35.8 1.0 0.5 26.6 6.2 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 29.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.3 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 0.0 0.1 22.2 0.0 15.7 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 19.8 22.6 0.0 0.0 0.0 1.7 0.0 0.2 0.0 7.8 0.0 0.1 0.0 0.1 0.0 0.0 14.8 11.2 0.0 0.0 0.0 0.0 12.6 0.7 1.8 171.0 0.5 144.2 15.9 139.7 155.6 0.7 54.5 121.2 135.4 3.7 121.0 1.1 0.9 268.9 126.8 0.1 0.2 0.0 0.2 0.3 0.5 0.9 0.2 0.4 1.4 0.2 0.3 3.1 3.2 10.5 1.0 27.1 2.0 0.1 0.0 2.8 0.1 9.7 5.3 0.8 0.0 3.1 9.2 0.0 0.1 107.1 0.5 46.9 0.5 58.1 12.3 1.6 2.4 1.2 9.0 7.0 2.0 0.1 1.1 7.7 14.0 120.1 0.0 7.5 28.7 0.3 0.0 1.4 1.1 0.0 5.4 3.1 156.1 1.5 3.8 1.8 12.2 2.6 1.6 213.1 0.5 1.6 1.3 0.3 0.7 31.0 0.2 0.8 2.0 1.5 0.3 6.6 0.7 1.1 46.4 9.9 0.7 1.3 0.3 147.0 1.2 0.3 0.6 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.9;liver: 11.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.1;Enteroendocrine cells: 3.6;Gastric mucus-secreting cells: 6.1;Hepatocytes: 2.8;Proximal enterocytes: 7.2;Respiratory ciliated cells: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 3.6" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" 0.1 0.2 0.9 0.3 0.9 0.0 0.2 1.8 1.4 0.3 0.0 2.8 3.2 0.3 0.7 0.3 0.3 1.7 0.2 0.8 0.9 1.8 11.3 0.2 0.0 0.6 0.7 0.3 1.0 0.2 1.0 0.0 0.7 0.6 3.7 0.5 0.3 0.2 0.2 0.4 3.9 0.2 0.2 0.3 3.4 0.1 1.0 0.1 0.5 0.3 0.2 0.3 0.2 0.8 0.2 0.2 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.2 0.1 0.2 0.1 0.4 0.5 0.0 0.0 0.2 0.3 0.1 0.2 0.2 0.8 0.6 1.3 0.5 0.1 0.0 0.1 0.1 0.6 0.2 0.8 0.6 0.1 0.2 0.5 0.3 0.3 0.2 0.2 0.4 0.0 3.6 0.2 0.0 0.1 0.2 0.2 1.4 0.5 0.3 0.1 0.2 0.1 0.1 0.5 0.1 0.3 0.3 0.5 0.4 0.5 0.3 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.8 1.4 0.8 0.9 0.6 0.7 0.7 0.2 1.0 0.8 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.3 0.3 0.6 0.0 0.5 0.0 0.0 0.0 0.0 4.1 1.9 0.4 0.0 0.4 0.3 0.2 3.6 0.0 0.9 1.1 0.1 0.1 6.1 0.3 0.0 0.3 0.7 2.8 0.0 0.0 0.8 1.5 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.5 1.9 0.0 0.0 0.4 7.2 1.7 4.1 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 2.4 0.5 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 407.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.8;Cytotrophoblasts: 106.6;Excitatory neurons: 65.0;Oligodendrocytes: 178.1;Proximal tubular cells: 245.9;Syncytiotrophoblasts: 79.4" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.1;EFO-21: 18.8;Hep G2: 56.1;HHSteC: 18.4;K-562: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" 1.3 2.4 12.5 0.7 22.8 0.2 1.9 16.5 16.1 2.0 4.9 0.8 0.3 1.8 1.0 0.9 2.4 1.9 1.0 10.1 16.2 407.6 21.7 1.4 0.6 18.3 19.5 4.5 9.0 0.2 2.6 43.2 19.0 6.3 0.5 1.1 4.9 0.8 1.0 2.2 0.4 1.9 12.5 0.6 4.7 8.7 19.9 1.1 1.4 0.3 0.7 1.8 1.4 37.4 0.1 0.0 1.6 5.6 8.3 7.7 16.1 3.5 2.0 1.9 1.4 0.0 0.1 0.2 18.8 0.2 0.1 2.1 0.1 2.6 4.5 0.0 0.6 6.8 0.4 56.1 18.4 0.1 4.8 10.5 7.5 10.9 5.4 5.4 0.0 0.0 15.3 0.3 0.0 0.6 0.1 0.7 10.3 0.2 0.0 0.2 0.0 0.1 1.2 0.4 0.7 0.2 0.0 4.0 0.8 1.0 2.9 0.3 0.2 0.1 4.0 8.7 0.1 0.5 1.2 0.1 0.6 0.0 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.0 12.5 22.8 16.5 16.1 10.1 16.2 18.3 19.5 19.0 12.5 19.9 37.4 0.3 0.0 2.2 53.8 3.8 1.3 1.0 0.8 6.2 0.7 1.2 1.7 1.7 0.0 0.5 7.3 0.0 106.6 0.0 0.1 15.6 0.2 23.3 0.5 2.0 0.6 0.0 0.0 65.0 0.9 7.1 2.3 3.1 0.8 0.0 3.0 0.4 17.5 9.5 0.0 40.3 0.0 0.0 0.3 0.7 27.8 3.1 2.0 0.0 11.2 0.0 0.4 0.0 24.1 178.1 0.9 0.0 0.4 1.2 3.5 0.0 245.9 6.4 0.2 0.0 0.4 1.0 6.6 1.2 1.2 0.6 79.4 1.5 2.2 0.0 0.6 SLC13A5 "INDY, NACT" ENSG00000141485 "Solute carrier family 13 member 5" Q86YT5 17 6684719-6713377 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "liver: 414.0" "Cell type enriched" "Detected in some" 15 "Hepatocytes: 381.0" "Cancer enriched" "Detected in some" 15 "liver cancer: 27.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 79 "Hep G2: 58.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044343 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA044343: AB_10961771" "unprognostic (8.46e-3)" "unprognostic (3.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.75e-2)" "unprognostic (7.33e-2)" "unprognostic (1.07e-1)" "unprognostic (6.79e-2)" "unprognostic (8.79e-3)" "unprognostic (1.32e-1)" "unprognostic (3.23e-1)" "unprognostic (1.26e-3)" "unprognostic (1.30e-3)" "unprognostic (3.78e-11)" "unprognostic (2.42e-2)" "unprognostic (2.46e-1)" "unprognostic (2.05e-2)" "unprognostic (2.04e-1)" 0.3 2.7 4.8 0.0 7.0 0.0 0.3 4.8 8.0 0.3 2.7 0.0 0.0 0.3 0.0 1.1 2.1 0.0 0.1 5.3 7.9 0.7 414.0 0.0 0.2 6.8 6.1 0.6 0.3 0.0 0.8 0.0 5.4 0.0 0.0 1.7 38.0 0.0 0.0 0.1 0.0 0.0 4.8 3.3 0.0 2.3 8.4 0.0 0.0 0.0 0.0 0.0 0.2 3.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 58.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 7.0 4.8 8.0 5.3 7.9 6.8 6.1 5.4 4.8 8.4 3.9 0.4 0.0 0.0 24.8 4.8 0.5 0.6 0.6 1.2 0.6 0.1 0.1 0.9 7.2 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.1 1.9 0.0 24.0 0.3 0.5 0.1 0.4 0.0 0.1 0.0 0.9 16.8 381.0 0.0 0.0 0.2 0.0 0.0 23.2 1.1 0.4 0.6 0.3 0.0 1.9 0.0 7.0 0.0 1.5 0.1 16.9 0.0 0.0 0.0 0.3 0.0 0.0 0.1 1.6 0.0 0.5 0.5 2.4 2.8 1.2 0.4 0.1 1.0 7.8 0.0 0.3 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.4;Granulosa cells: 322.8;Muller glia cells: 184.8;Rod photoreceptor cells: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: AB_2686337" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavorable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" 20.7 10.4 35.7 11.8 36.1 4.3 7.5 37.8 99.4 7.1 37.8 46.8 32.5 28.6 22.8 15.3 13.1 14.8 67.9 33.5 35.2 11.4 55.6 4.9 9.5 38.6 35.9 7.9 2.0 10.0 5.2 34.0 37.0 14.4 35.3 68.9 3.5 11.2 67.5 13.0 16.6 39.2 37.0 6.6 26.6 29.8 38.3 11.7 8.6 59.6 11.6 11.9 7.1 38.2 111.1 24.0 86.9 74.3 61.9 52.1 272.7 64.6 51.1 52.0 80.9 85.4 67.1 113.8 82.3 61.6 32.6 113.1 126.3 124.8 96.8 75.6 105.2 108.9 63.4 112.9 104.6 123.2 9.9 72.2 144.6 75.7 146.4 79.2 131.4 53.8 131.3 78.0 61.9 19.9 70.2 70.1 271.4 36.7 74.5 67.9 130.7 92.8 67.3 1.9 86.9 46.5 121.8 3.8 97.5 130.0 3.7 48.9 80.9 45.4 72.0 89.3 93.1 39.7 33.9 116.7 137.1 78.5 56.0 0.0 1.4 0.0 1.5 1.6 1.7 0.9 1.8 2.0 2.5 0.3 0.8 1.5 0.1 0.6 0.3 0.2 6.1 0.8 35.7 36.1 37.8 99.4 33.5 35.2 38.6 35.9 37.0 37.0 38.3 38.2 15.1 0.0 2.6 8.5 16.5 89.3 6.5 39.9 87.6 16.9 16.5 9.9 126.3 10.0 5.7 0.0 158.4 77.4 20.3 99.8 0.0 2.5 107.2 14.3 70.7 22.8 3.5 20.2 9.8 3.3 67.6 32.8 67.2 35.8 8.9 322.8 6.4 37.5 15.4 20.2 11.6 17.3 20.3 9.0 15.7 118.3 11.8 12.8 39.2 20.6 4.3 184.8 0.0 9.0 23.8 7.4 7.7 7.5 25.5 16.5 9.3 10.8 3.9 277.5 0.0 38.2 22.1 45.3 23.6 29.6 39.5 46.0 20.9 49.6 23.3 1.3 SLC16A10 "MCT10, TAT1" ENSG00000112394 "Solute carrier family 16 member 10" Q8TF71 6 111087503-111231194 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 53.7;skeletal muscle: 41.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.8;Excitatory neurons: 33.9;Inhibitory neurons: 47.8;Macrophages: 33.8;Melanocytes: 44.4" "Cancer enriched" "Detected in many" 6 "testis cancer: 4.5" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.7;T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 49.4;HEK 293: 20.2;RPMI-8226: 37.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA016860 Approved Supported "Vesicles,Cell Junctions" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Cell Junctions" "HPA016860: AB_2189211" "unprognostic (2.03e-1)" "unprognostic (2.08e-1)" "unprognostic (6.11e-2)" "unprognostic (3.56e-4)" "unprognostic (2.24e-1)" "unprognostic (2.15e-1)" "unprognostic (1.64e-1)" "unprognostic (1.89e-1)" "unprognostic (1.86e-3)" "unprognostic (5.22e-1)" "unprognostic (1.74e-2)" "unprognostic (1.06e-1)" "unprognostic (1.10e-3)" "unprognostic (2.73e-1)" "unprognostic (1.60e-1)" "unprognostic (1.33e-1)" "unprognostic (1.91e-1)" 2.9 5.5 1.4 3.0 8.6 0.8 0.8 4.2 3.4 0.6 53.7 1.2 8.5 0.5 1.4 0.8 0.8 1.5 2.3 2.0 1.2 10.0 13.5 4.6 0.9 1.1 5.0 0.9 29.7 7.9 1.0 23.7 2.8 1.3 1.8 0.7 3.1 0.2 41.2 15.3 5.0 0.3 0.2 1.8 5.3 4.2 9.6 10.9 2.7 6.0 1.3 1.9 1.2 1.1 0.9 1.0 0.4 2.2 0.1 0.1 3.1 0.0 0.2 0.8 1.2 9.0 0.4 5.2 1.4 0.3 2.5 0.1 49.4 0.1 1.0 0.1 20.2 8.2 0.7 7.4 0.1 7.6 7.4 0.0 0.0 0.1 0.0 0.2 0.0 10.9 1.4 0.2 0.1 3.6 9.8 0.8 14.6 0.2 3.2 5.4 6.8 37.2 0.0 0.5 10.7 3.3 0.2 0.7 1.8 3.6 1.8 0.9 0.1 0.1 1.8 0.5 2.5 2.6 0.1 1.5 0.3 5.8 0.8 0.4 0.0 0.0 0.1 0.0 0.1 0.1 0.4 0.1 0.0 0.2 1.7 1.5 0.3 0.1 0.0 0.1 1.6 0.1 1.4 8.6 4.2 3.4 2.0 1.2 1.1 5.0 2.8 0.2 9.6 1.1 0.4 9.6 32.8 2.0 1.5 9.7 10.7 0.0 4.6 6.9 2.0 1.3 9.1 0.0 3.1 5.5 2.1 1.9 0.7 2.1 1.9 0.2 9.0 0.4 0.8 1.4 6.6 1.7 33.9 12.5 1.8 8.9 3.6 1.3 1.3 2.5 4.2 25.4 21.4 1.7 47.8 4.8 0.0 12.4 12.4 8.2 0.0 33.8 44.4 0.0 0.7 1.6 0.0 16.6 0.3 2.0 0.9 0.0 4.8 3.9 10.9 17.7 0.7 0.7 0.0 18.5 1.0 11.6 11.2 1.2 14.8 1.2 5.8 9.2 8.5 1.2 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Hepatocytes: 63.7;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 83.9;GAMG: 70.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" 13.8 24.7 4.6 4.8 5.8 0.0 5.4 1.7 5.7 9.4 1.2 7.0 3.3 10.3 1.7 2.9 9.3 6.0 10.4 7.7 4.9 7.9 40.7 7.5 0.9 5.6 3.9 12.8 5.5 11.7 9.8 9.2 1.8 6.2 1.8 1.1 5.0 5.8 2.7 2.5 3.1 6.9 3.5 1.2 4.7 0.9 8.1 5.7 12.6 3.7 1.8 6.6 6.2 3.0 8.4 10.4 7.2 43.1 20.8 11.1 0.0 83.9 29.7 38.2 20.6 0.1 0.9 0.0 1.3 37.5 70.8 1.7 1.1 40.2 22.1 6.1 3.6 0.0 0.0 0.0 1.5 0.0 0.0 16.5 9.5 19.3 23.3 14.6 0.1 0.1 0.0 0.0 9.1 0.0 0.5 2.7 27.2 0.0 7.8 17.4 19.9 0.0 18.0 0.1 1.9 12.0 9.6 50.2 0.3 2.5 0.6 1.1 0.0 32.5 8.8 35.7 41.9 0.0 0.0 0.0 34.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 1.7 5.7 7.7 4.9 5.6 3.9 1.8 3.5 8.1 3.0 5.6 0.0 0.6 22.2 0.2 0.8 4.3 2.4 0.6 5.7 4.3 3.4 4.5 8.6 2.9 3.7 0.0 5.7 0.1 0.0 3.9 4.3 0.1 0.3 9.8 6.1 8.4 0.0 14.5 2.4 4.9 11.8 0.5 0.5 2.5 1.7 3.6 63.7 1.0 3.3 21.6 0.3 0.0 1.3 0.8 1.2 15.2 0.1 3.6 15.9 0.6 6.2 0.0 23.1 7.1 4.6 0.0 20.7 0.1 5.1 0.4 4.7 2.4 1.5 13.1 9.7 5.6 0.1 0.1 0.9 1.3 2.1 0.4 1.4 0.2 4.9 SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1667.1;Syncytiotrophoblasts: 748.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" 30.4 16.9 3.8 25.3 5.8 22.7 15.7 6.6 9.7 26.2 5.0 28.9 11.6 11.6 1.3 42.4 18.5 12.8 26.0 4.5 7.3 48.2 11.3 46.4 5.7 17.3 8.5 9.1 5.8 2.5 12.1 24.7 11.9 19.6 5.7 5.7 27.5 5.9 198.3 8.4 22.9 6.0 8.4 57.5 22.0 32.0 13.8 2.9 29.1 73.2 5.2 26.3 28.5 15.1 52.8 24.4 0.6 1.3 7.8 28.8 51.7 225.6 107.7 117.4 142.2 10.1 119.1 0.7 158.0 122.5 127.9 18.9 15.6 242.0 51.8 78.1 1.2 87.4 144.0 236.4 164.1 105.2 111.5 64.8 38.2 77.0 38.5 185.8 69.1 2.2 1.0 26.6 116.1 14.0 1.4 166.3 1.9 22.1 223.5 0.9 1.6 33.2 75.9 3.0 2.9 1.7 196.7 166.9 3.2 20.4 25.4 131.4 124.0 281.7 5.1 4.5 200.9 97.3 1.9 3.9 140.2 94.7 3.0 56.6 32.6 92.1 9.6 30.4 13.4 8.1 7.7 10.5 24.1 6.2 4.2 5.3 109.1 25.3 31.4 15.2 7.3 16.0 3.8 5.8 6.6 9.7 4.5 7.3 17.3 8.5 11.9 8.4 13.8 15.1 19.2 9.6 9.8 3.6 27.9 6.5 47.5 210.1 2.8 13.4 3.2 2.5 6.1 4.3 182.3 57.0 4.2 67.6 72.4 216.7 0.0 136.1 3.0 33.7 15.4 29.9 20.9 9.1 0.3 18.0 1667.1 17.2 45.3 65.1 75.0 15.9 16.8 1.1 271.0 127.9 0.3 28.3 148.5 99.9 84.6 3.8 3.1 168.6 14.2 9.4 184.9 20.3 40.2 0.0 1.0 305.5 190.2 3.8 35.7 16.5 62.4 5.6 91.1 11.6 0.0 1.6 50.5 1.9 9.5 1.6 6.7 748.8 38.5 0.8 33.4 119.6 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC16A9 "C10orf36, FLJ43803, MCT9" ENSG00000165449 "Solute carrier family 16 member 9" Q7RTY1 10 59650764-59736002 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 151.3;kidney: 191.1" "Group enriched" "Detected in many" 4 "Astrocytes: 83.9;Distal enterocytes: 108.6;Proximal tubular cells: 252.6;Theca cells: 99.4" "Cancer enhanced" "Detected in many" "renal cancer: 21.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 10.8;NTERA-2: 20.1;SuSa: 10.1;U-251 MG: 10.6;U-937: 18.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049286 Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Cell Junctions" "HPA049286: AB_2680699" "unprognostic (3.39e-2)" "unprognostic (6.91e-2)" "unprognostic (1.30e-1)" "unprognostic (1.27e-1)" "unprognostic (1.60e-3)" "unprognostic (1.76e-2)" "unprognostic (5.96e-2)" "unprognostic (3.50e-3)" "unprognostic (5.01e-2)" "unprognostic (2.11e-3)" "unprognostic (5.99e-2)" "unprognostic (4.60e-2)" "prognostic favorable (2.56e-6)" "unprognostic (7.57e-3)" "unprognostic (1.27e-2)" "unprognostic (3.72e-1)" "unprognostic (1.94e-1)" 1.2 151.3 12.8 1.2 12.8 1.7 1.7 11.9 14.8 18.5 18.4 12.5 0.4 16.2 5.2 10.9 22.0 3.1 3.4 12.9 16.6 191.1 2.5 1.1 1.7 14.0 13.7 34.1 3.0 29.2 6.9 0.1 12.0 7.8 16.7 5.6 2.9 10.2 4.3 0.4 1.2 7.2 13.3 40.8 6.0 8.9 12.3 1.2 13.9 2.8 2.8 2.2 9.0 15.0 0.0 0.3 5.2 6.8 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.3 0.0 0.7 0.0 0.0 0.9 10.8 0.0 0.0 0.0 1.8 0.1 0.3 0.1 0.1 2.3 0.0 0.5 0.2 0.0 2.8 0.1 0.4 5.4 8.0 0.1 0.6 4.2 3.0 0.0 20.1 2.0 9.3 3.6 0.2 7.2 0.0 0.3 3.4 9.6 0.1 0.4 0.0 10.1 3.4 4.5 3.2 0.5 1.1 0.1 10.6 0.0 0.0 0.0 0.0 18.6 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 12.8 11.9 14.8 12.9 16.6 14.0 13.7 12.0 13.3 12.3 15.0 0.3 0.0 0.0 83.9 1.0 0.1 2.1 9.4 0.6 4.3 3.1 1.5 3.9 0.0 26.2 7.3 0.0 0.0 0.0 108.6 25.4 1.0 0.2 2.3 2.0 1.5 20.0 4.2 2.5 0.0 1.7 4.1 3.6 2.4 0.0 28.4 0.4 0.0 0.1 3.3 4.8 19.1 4.1 18.8 0.7 1.5 13.7 1.5 3.6 1.9 0.6 11.8 0.0 14.6 1.0 0.1 23.2 12.0 0.0 17.7 2.2 252.6 7.4 1.0 0.0 2.4 3.4 0.3 0.2 17.0 0.1 0.0 0.7 99.4 11.9 6.5 SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 310.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.9;ASC TERT1: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" 10.4 10.5 5.9 6.4 6.0 6.8 13.8 6.2 7.0 10.7 5.9 20.4 16.4 9.4 44.6 8.4 5.3 10.4 8.5 6.5 8.5 31.9 17.6 13.2 5.3 6.5 7.0 4.0 11.6 310.5 9.9 21.7 7.8 16.8 22.1 18.3 30.3 14.7 5.4 7.1 21.1 10.6 5.7 7.0 14.4 6.1 7.1 4.5 43.5 6.2 5.6 12.6 6.3 7.6 7.4 9.9 9.7 15.6 99.9 74.2 12.8 23.8 59.4 6.3 22.0 6.6 17.6 6.8 11.2 32.9 14.8 12.6 13.7 5.9 11.2 4.8 15.5 2.8 5.1 15.4 19.4 5.6 10.8 34.2 8.8 14.2 9.7 26.4 16.2 9.0 7.1 7.2 22.3 4.9 2.3 3.3 7.1 30.9 5.7 5.0 12.1 28.5 16.0 20.2 3.8 6.7 4.8 14.0 14.4 14.0 6.3 34.1 23.5 3.0 2.8 12.1 5.7 20.4 30.6 1.9 10.5 11.6 9.0 13.3 7.9 3.3 6.0 7.4 5.8 3.9 6.6 5.8 7.6 2.4 5.4 6.0 5.7 8.9 4.8 5.5 6.6 4.9 5.9 6.0 6.2 7.0 6.5 8.5 6.5 7.0 7.8 5.7 7.1 7.6 8.8 22.4 20.7 16.3 8.2 9.6 13.2 13.7 5.7 8.2 22.6 5.5 6.8 18.6 17.4 51.5 29.2 19.4 11.0 46.4 3.9 14.2 36.6 16.6 7.8 13.8 12.1 3.8 47.7 13.7 13.5 25.8 14.8 19.6 14.5 3.2 23.9 32.9 64.6 0.0 46.8 47.7 20.3 24.8 22.7 48.3 7.5 25.4 10.6 14.0 11.2 8.3 13.4 17.6 16.3 19.2 17.5 11.3 20.6 29.1 23.9 36.3 21.5 28.9 0.0 10.5 9.1 8.4 3.6 10.2 11.2 22.8 11.0 2.9 19.2 30.7 SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 82.6" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 158.0;Syncytiotrophoblasts: 362.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 102.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 102.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA024802: AB_10602892" "unprognostic (4.31e-3)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.23e-2)" "unprognostic (2.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "unprognostic (2.87e-3)" "unprognostic (4.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.07e-10)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (7.97e-5)" "unprognostic (3.10e-1)" 7.7 9.4 8.2 5.7 4.0 8.1 5.9 5.6 12.4 10.0 82.6 6.8 22.5 6.4 0.9 3.2 6.9 1.9 4.2 11.8 2.7 8.0 20.9 15.7 4.2 5.3 5.2 11.8 6.9 0.8 5.4 13.6 6.0 5.8 0.8 2.3 3.3 0.8 2.6 3.9 7.9 1.1 3.0 15.1 7.4 4.6 6.6 2.2 13.8 0.5 0.7 4.3 5.2 4.1 28.9 23.7 4.9 19.4 1.5 2.1 40.2 12.5 1.9 11.1 7.0 55.1 26.1 26.8 24.9 2.8 9.1 14.1 9.0 8.5 2.7 25.2 51.2 54.7 12.4 38.8 6.1 37.2 8.5 2.7 6.3 11.6 3.3 3.3 9.1 27.3 67.6 11.8 3.5 29.3 49.6 29.9 28.5 11.2 30.0 66.5 5.4 79.2 4.6 16.9 29.7 26.7 14.9 23.5 11.2 6.7 18.4 41.4 10.7 14.6 18.8 4.3 21.1 4.8 18.5 23.5 6.7 56.4 11.9 1.6 18.5 24.1 0.9 16.3 2.8 2.5 1.4 2.0 13.4 0.8 2.0 1.5 102.9 1.1 10.8 4.1 3.2 7.9 8.2 4.0 5.6 12.4 11.8 2.7 5.3 5.2 6.0 3.0 6.6 4.1 1.4 48.1 6.3 13.7 2.9 2.4 2.0 2.6 1.8 23.6 3.9 3.4 2.5 1.5 6.2 0.0 0.0 158.0 0.5 8.2 0.0 8.0 3.7 2.2 5.8 3.4 0.0 6.7 3.4 4.9 21.5 3.7 4.1 4.5 1.3 12.7 1.1 16.2 27.3 8.4 4.0 4.1 8.2 11.1 5.0 6.6 6.5 8.6 3.6 23.4 8.3 5.7 0.0 2.0 1.7 7.6 5.4 11.3 9.4 4.6 20.5 2.4 0.9 3.6 0.0 3.3 4.1 1.5 4.8 1.8 1.6 362.4 2.6 5.1 8.5 0.9 SLC19A3 THTR2 ENSG00000135917 "Solute carrier family 19 member 3" Q9BZV2 2 227683763-227718028 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 46.7;breast: 28.4;placenta: 24.1" "Group enriched" "Detected in many" 4 "Cytotrophoblasts: 65.4;Syncytiotrophoblasts: 160.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 6.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC diff: 13.9;BEWO: 6.2;CACO-2: 20.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038898 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane, Cytosol" "HPA038898: AB_10673481" "unprognostic (3.37e-2)" "unprognostic (3.59e-5)" "unprognostic (1.95e-3)" "unprognostic (1.24e-2)" "unprognostic (1.22e-1)" "unprognostic (6.82e-2)" "unprognostic (1.93e-2)" "unprognostic (1.67e-1)" "unprognostic (1.19e-1)" "unprognostic (2.04e-1)" "unprognostic (4.67e-2)" "unprognostic (3.12e-3)" "unprognostic (7.28e-2)" "unprognostic (8.20e-2)" "unprognostic (1.68e-1)" "unprognostic (1.71e-2)" "unprognostic (7.01e-3)" 46.7 0.6 5.0 1.9 3.3 1.2 28.4 4.7 4.3 0.5 1.0 2.6 9.1 0.5 0.1 0.7 0.5 5.7 0.7 3.4 4.4 2.2 13.8 4.1 0.8 5.2 4.2 0.9 1.7 0.1 0.1 24.1 5.4 0.3 1.8 2.2 1.1 0.1 0.9 1.6 5.6 0.4 4.4 0.5 0.5 0.5 5.7 0.2 0.4 0.8 0.4 1.0 0.4 4.0 0.3 0.9 0.2 0.8 13.9 0.3 6.2 0.1 0.2 0.2 0.6 20.2 0.4 0.2 0.1 0.1 4.6 0.4 0.6 0.5 0.8 0.0 1.0 0.1 1.1 0.8 1.8 0.2 0.1 3.4 0.4 0.1 0.8 0.3 0.0 0.3 0.1 0.6 0.0 1.6 0.1 0.5 3.0 0.7 0.1 0.3 0.1 0.2 0.2 0.2 0.9 0.1 0.3 1.9 0.5 2.6 0.2 0.2 0.6 0.4 0.4 4.1 0.4 0.1 0.1 0.6 1.4 0.2 0.5 6.8 0.8 1.0 0.4 0.6 0.3 0.8 0.4 0.4 0.2 1.3 0.5 0.5 3.3 2.2 0.7 1.0 0.2 0.3 5.0 3.3 4.7 4.3 3.4 4.4 5.2 4.2 5.4 4.4 5.7 4.0 0.2 9.6 5.1 2.3 0.0 0.0 0.5 0.0 0.6 5.3 0.2 0.1 0.4 5.7 0.0 1.8 0.0 65.4 0.1 5.7 1.9 4.4 0.3 0.1 0.0 2.6 1.2 0.0 0.4 0.0 7.4 3.2 0.0 0.1 0.0 0.3 0.0 13.1 5.1 0.0 0.9 1.6 0.0 0.6 0.0 0.7 0.3 0.9 0.0 25.3 0.0 0.8 0.0 4.5 0.3 0.4 1.0 0.0 0.1 0.4 9.3 3.0 0.0 0.2 0.0 1.7 1.6 0.0 0.3 0.0 0.0 160.6 0.2 0.1 6.5 0.4 SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.6;Erythroid cells: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 95.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" 97.2 15.9 5.8 29.6 6.5 60.9 77.7 6.6 6.1 57.4 6.1 50.1 16.2 39.1 98.0 98.0 48.9 36.5 26.4 5.9 8.5 45.6 8.1 65.3 27.9 15.8 11.1 45.8 73.2 2.9 24.5 46.9 13.3 98.6 42.4 1.4 120.5 77.0 8.5 55.7 36.2 33.0 9.5 40.4 55.5 40.3 9.8 19.9 14.1 10.7 30.3 109.6 83.0 11.5 179.6 323.6 76.3 116.1 194.7 164.3 180.0 249.6 283.0 183.2 264.1 296.1 197.1 194.8 118.9 624.2 105.2 281.1 224.9 296.9 135.5 130.1 203.7 324.3 115.1 281.9 501.3 228.2 182.9 268.6 727.3 215.5 541.1 61.3 98.9 255.0 348.9 500.1 99.5 304.5 105.4 611.1 134.0 636.5 140.9 117.8 86.5 282.7 104.2 384.8 117.3 86.0 123.4 331.8 275.4 58.8 191.6 296.6 74.1 109.4 174.1 86.4 205.7 308.0 325.3 164.0 206.3 281.0 274.3 0.1 36.1 2.9 14.1 55.0 11.4 17.8 8.0 9.9 50.2 8.1 1.9 6.0 1.0 21.0 66.3 95.8 15.5 27.8 5.8 6.5 6.6 6.1 5.9 8.5 15.8 11.1 13.3 9.5 9.8 11.5 63.6 0.0 17.3 0.0 31.1 57.7 148.6 95.9 64.9 0.2 52.0 43.1 20.3 21.5 41.2 0.0 0.0 80.8 86.3 44.6 3.9 38.5 27.0 2.6 32.9 29.0 10.7 143.3 0.6 65.7 129.3 48.0 21.9 2.7 29.2 20.9 29.6 0.7 38.4 0.0 0.8 111.3 40.7 21.6 34.7 14.0 19.0 39.8 19.6 3.7 26.0 0.6 12.3 0.0 0.6 43.4 74.8 19.5 68.6 59.0 6.5 23.1 13.0 0.8 6.6 15.8 44.0 35.9 4.0 69.0 28.3 24.4 38.7 6.1 62.9 100.0 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC23A3 "FLJ31168, SVCT3, Yspl1" ENSG00000213901 "Solute carrier family 23 member 3" Q6PIS1 2 219161465-219170095 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 8 "intestine: 18.4;kidney: 45.6" "Group enriched" "Detected in many" 5 "Proximal enterocytes: 55.9;Proximal tubular cells: 14.4" "Cancer enriched" "Detected in some" 9 "renal cancer: 5.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 4.9;U-266/70: 3.1" "Region enhanced" "Detected in single" "cerebral cortex: 1.3" "Not detected" "Not detected" HPA019059 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 45: Enterocytes - Digestion" Nucleoplasm "Cell Junctions" "HPA019059: AB_1857017" "unprognostic (2.49e-2)" "unprognostic (6.65e-2)" "unprognostic (2.05e-4)" "unprognostic (6.97e-2)" "unprognostic (8.41e-2)" "unprognostic (1.22e-2)" "unprognostic (9.07e-2)" "unprognostic (1.93e-1)" "unprognostic (4.01e-2)" "unprognostic (4.35e-2)" "unprognostic (3.10e-1)" "unprognostic (6.12e-4)" "unprognostic (9.42e-2)" "unprognostic (6.48e-2)" "unprognostic (2.41e-2)" "unprognostic (3.34e-1)" "unprognostic (6.52e-5)" 1.1 0.4 1.0 0.9 1.0 0.1 0.9 1.2 0.9 2.8 1.0 3.8 7.6 1.6 0.5 2.2 1.5 0.5 1.0 1.0 1.0 45.6 4.0 1.3 0.7 1.1 1.0 1.8 1.1 0.8 0.5 1.0 1.0 2.4 1.5 0.2 1.0 0.6 0.2 1.9 18.4 0.7 1.0 1.5 1.2 0.1 1.1 0.3 2.4 0.1 0.8 1.1 2.3 1.0 0.5 0.2 0.1 0.6 2.0 1.1 0.4 1.2 0.3 0.2 0.7 1.1 0.7 0.2 0.4 0.8 0.0 1.7 0.4 0.1 0.3 1.1 0.9 1.1 1.2 0.1 0.4 0.1 0.4 0.4 4.9 0.4 1.5 1.9 0.6 0.6 0.1 0.4 0.3 0.2 0.0 0.5 0.0 0.4 0.1 0.3 0.3 0.4 1.6 1.9 0.2 0.5 0.1 0.0 1.3 0.5 0.5 0.5 1.4 1.1 0.7 1.0 0.4 3.1 0.1 1.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 1.2 0.9 1.0 1.0 1.1 1.0 1.0 1.0 1.1 1.0 0.6 0.0 0.5 0.0 1.7 1.5 1.4 0.5 0.6 1.1 0.9 1.1 0.3 1.5 0.3 1.8 0.0 0.3 0.5 3.8 1.9 0.2 0.0 0.2 0.8 1.0 1.8 0.4 0.3 0.0 0.1 0.8 0.0 0.9 0.0 0.5 1.1 1.2 0.2 0.0 0.3 4.0 0.0 0.9 0.8 0.0 1.5 1.0 1.8 1.0 1.1 1.2 0.0 0.0 0.0 0.4 6.0 1.2 0.2 1.5 55.9 14.4 0.1 0.2 0.0 0.8 1.0 0.0 0.2 0.7 1.6 0.4 0.8 0.6 3.9 0.9 SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19786928 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 117.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 2710.1" "Group enriched" "Detected in some" 4 "breast cancer: 0.5;glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 2.6;SCLC-21H: 2.2;U-87 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA079359: " "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.48e-2)" "unprognostic (8.46e-2)" "unprognostic (8.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-2)" "unprognostic (6.51e-2)" "unprognostic (1.57e-2)" "unprognostic (2.08e-4)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (1.51e-2)" 0.1 5.9 28.4 0.0 64.7 0.1 0.0 42.3 64.6 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.1 0.0 19.2 19.1 0.1 0.0 0.0 0.0 81.3 36.3 0.0 0.0 0.0 0.8 0.1 87.7 0.1 0.0 18.7 0.0 0.0 0.1 0.1 0.0 0.0 19.4 0.1 0.1 0.2 81.9 0.0 0.0 0.3 0.0 0.0 0.0 117.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 28.4 64.7 42.3 64.6 19.2 19.1 81.3 36.3 87.7 19.4 81.9 117.1 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 58.7 0.0 0.0 2.3 0.0 0.0 0.0 273.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 668.6 0.0 0.1 0.9 0.0 0.1 0.0 0.0 1.4 0.0 0.1 97.6 637.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 25.3 0.0 4.1 0.0 217.6 2710.1 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 10.4 0.0 3.2 0.2 0.2 0.7 0.0 0.1 0.3 0.0 0.0 0.1 0.0 SLC24A4 NCKX4 ENSG00000140090 "Solute carrier family 24 member 4" Q8NFF2 14 92322581-92501481 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 92.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 251.6;Cone photoreceptor cells: 200.1" "Group enriched" "Detected in some" 5 "glioma: 0.5;melanoma: 0.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 11.1;intermediate monocyte: 14.7;non-classical monocyte: 11.6" "Lineage enriched" "Detected in many" 5 "monocytes: 14.7" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063206 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA063206: " "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (3.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-3)" "unprognostic (3.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (3.21e-1)" "unprognostic (1.48e-3)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.58e-2)" 0.5 0.2 7.1 1.4 10.3 3.5 0.1 17.5 8.1 0.2 92.6 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.2 7.2 5.3 0.0 0.1 0.8 1.2 22.7 14.1 0.2 0.1 0.0 1.4 0.3 19.1 0.2 0.2 12.3 0.1 0.3 0.8 0.1 0.3 0.4 14.7 2.7 0.1 1.1 16.5 0.4 0.1 1.0 0.4 0.3 0.2 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.1 0.0 0.0 14.7 0.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.5 0.1 11.6 0.5 0.0 2.7 7.1 10.3 17.5 8.1 7.2 5.3 22.7 14.1 19.1 14.7 16.5 12.9 0.8 0.0 1.9 47.0 0.4 0.0 0.1 0.0 0.0 251.6 0.3 0.1 1.8 0.0 0.0 0.0 200.1 0.0 0.1 0.0 0.0 0.0 4.0 0.5 0.1 0.9 0.0 0.8 19.9 0.0 0.1 0.5 0.0 0.8 0.0 0.0 1.1 0.0 4.0 0.0 28.5 0.0 0.0 22.2 1.8 5.6 0.3 16.6 0.0 2.8 44.3 4.1 1.0 10.1 1.3 0.1 0.0 0.4 0.1 0.2 0.0 0.2 0.7 10.6 0.0 9.9 0.2 0.1 1.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 SLC26A9 ENSG00000174502 "Solute carrier family 26 member 9" Q7LBE3 1 205913048-205943460 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "salivary gland: 72.4;stomach 1: 33.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 50.1;Cardiomyocytes: 26.2;Gastric mucus-secreting cells: 29.0;Proximal tubular cells: 25.4" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;Hep G2: 5.1;OE19: 22.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA051485 Enhanced Approved "Cell Junctions" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 11: Alveolar cells - Smell perception" "Cell Junctions" "HPA051485: AB_2681503" "unprognostic (1.55e-2)" "unprognostic (2.70e-2)" "unprognostic (8.77e-2)" "unprognostic (3.14e-1)" "unprognostic (1.83e-2)" "prognostic favorable (8.55e-5)" "unprognostic (1.26e-1)" "unprognostic (1.68e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (8.85e-2)" "unprognostic (3.41e-1)" "unprognostic (2.43e-1)" "unprognostic (2.19e-1)" "unprognostic (1.05e-1)" "unprognostic (7.45e-3)" "unprognostic (2.01e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.1 1.3 0.2 0.0 0.0 0.1 0.0 7.7 0.0 0.3 0.3 0.0 0.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 72.4 0.0 0.0 2.0 0.0 0.0 0.0 0.0 33.9 0.0 0.1 0.0 0.4 0.3 5.3 0.0 0.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.3 0.3 0.3 0.0 0.1 0.1 0.0 3.2 50.1 1.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 26.2 0.0 2.7 1.8 0.0 0.0 0.0 0.0 1.9 4.3 0.5 0.2 0.0 0.3 0.0 0.0 0.1 2.2 0.0 1.7 29.0 0.2 2.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.2 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.5 0.0 0.0 0.0 0.4 0.0 25.4 2.3 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.5 1.5 0.0 0.4 SLC27A1 "ACSVL5, FATP, FATP1, FLJ00336, MGC71751" ENSG00000130304 "Solute carrier family 27 member 1" Q6PCB7 19 17468769-17506168 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fatty acid metabolism, Lipid metabolism, Lipid transport, Transport" Ligase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Oligodendrocytes: 67.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 27.7;SK-MEL-30: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076520 Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Mitochondria, Cytosol" "HPA076520: AB_2732311" "unprognostic (1.48e-3)" "unprognostic (3.03e-2)" "unprognostic (5.72e-3)" "unprognostic (5.84e-2)" "unprognostic (2.16e-3)" "unprognostic (4.36e-2)" "unprognostic (8.56e-2)" "unprognostic (3.36e-2)" "unprognostic (9.03e-2)" "unprognostic (1.85e-2)" "unprognostic (1.12e-1)" "unprognostic (2.28e-1)" "prognostic favorable (4.70e-4)" "unprognostic (5.01e-2)" "unprognostic (2.25e-1)" "unprognostic (1.02e-1)" "unprognostic (1.12e-1)" 18.5 24.2 32.9 4.5 41.5 1.5 19.3 37.3 39.0 22.0 45.9 15.2 3.6 13.1 2.9 8.5 17.0 8.2 29.0 32.0 32.8 10.9 7.9 10.4 4.7 41.1 40.3 33.0 14.4 17.7 19.3 6.2 38.6 23.2 1.8 4.0 24.1 10.3 24.9 14.4 7.6 3.9 34.4 10.5 13.7 17.5 35.9 2.2 16.8 12.4 1.6 13.9 14.0 46.7 6.2 3.0 4.1 9.8 27.7 15.2 3.5 4.4 11.2 4.8 7.2 0.5 18.2 2.1 8.1 7.2 4.3 7.3 0.4 6.8 1.3 2.4 1.4 1.2 0.5 2.3 5.4 0.5 6.4 14.1 4.6 4.8 1.9 19.7 3.3 3.9 0.8 1.3 3.2 2.5 3.3 4.9 1.2 6.0 5.2 4.7 3.2 1.4 3.2 1.8 1.4 2.9 3.0 1.5 47.8 2.5 5.2 1.6 2.1 9.4 6.1 7.5 3.0 4.0 3.1 0.7 9.6 5.3 6.7 0.0 9.2 0.2 1.4 4.0 2.6 0.4 1.0 1.7 6.3 0.3 1.3 1.7 0.0 1.6 1.8 6.5 0.7 4.6 32.9 41.5 37.3 39.0 32.0 32.8 41.1 40.3 38.6 34.4 35.9 46.7 19.7 3.2 11.9 84.5 1.8 6.6 14.1 12.7 10.2 8.4 15.5 26.9 19.5 11.5 11.1 9.2 27.1 4.3 8.3 1.2 1.9 11.1 1.1 8.4 6.9 7.8 5.4 0.8 16.1 4.8 15.6 10.4 9.2 4.9 2.5 8.4 10.4 8.1 26.1 6.7 23.9 3.0 6.1 22.4 4.0 2.5 21.5 13.4 8.8 15.0 14.7 11.6 4.1 37.2 67.5 5.2 0.6 11.7 1.7 12.0 0.1 3.6 16.1 17.7 6.6 10.9 7.3 9.1 5.8 5.0 4.5 2.3 4.9 13.8 2.2 8.7 SLC28A1 CNT1 ENSG00000156222 "Solute carrier family 28 member 1" O00337 15 84884654-84945798 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 21 "intestine: 49.1;kidney: 48.2;liver: 111.3" "Group enriched" "Detected in some" 5 "Hepatocytes: 38.6;Hofbauer cells: 54.3;Proximal enterocytes: 86.9;Proximal tubular cells: 93.4" "Group enriched" "Detected in some" 63 "liver cancer: 10.9;renal cancer: 33.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA019551, HPA056247" Enhanced Approved "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nuclear speckles, Cytosol" "HPA019551: AB_2670187, HPA056247: " "unprognostic (3.81e-2)" "unprognostic (1.60e-1)" "unprognostic (2.22e-1)" "unprognostic (7.49e-2)" "unprognostic (5.08e-2)" "unprognostic (7.08e-2)" "unprognostic (8.68e-3)" "unprognostic (1.82e-1)" "unprognostic (1.98e-1)" "unprognostic (2.18e-2)" "unprognostic (1.63e-1)" "unprognostic (8.37e-2)" "unprognostic (1.35e-1)" "unprognostic (7.42e-2)" "unprognostic (7.72e-3)" "unprognostic (6.65e-2)" "unprognostic (1.55e-1)" 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.2 0.1 0.3 0.0 0.0 37.9 0.0 0.5 0.1 0.7 0.2 1.0 0.1 0.3 48.2 111.3 0.0 0.2 0.9 0.3 0.0 0.0 0.2 0.2 1.2 0.7 0.0 0.0 0.0 0.1 0.0 1.5 0.0 49.1 0.0 0.4 0.0 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.3 0.9 0.3 0.7 0.4 0.2 0.6 0.2 0.0 0.0 0.3 0.0 0.0 0.0 1.0 0.0 0.0 0.5 0.3 2.2 4.3 0.6 7.3 0.0 0.5 0.0 0.0 11.7 3.0 0.0 0.4 0.1 0.1 0.0 0.0 0.5 0.0 0.5 0.4 0.0 0.6 0.0 0.0 0.4 38.6 54.3 0.0 0.5 2.8 0.0 0.6 0.0 0.0 0.0 0.9 0.0 0.0 0.6 0.0 0.0 0.5 1.1 0.3 2.5 0.0 0.0 0.0 86.9 93.4 1.4 0.0 0.0 2.6 0.2 0.0 0.0 0.0 0.0 0.8 0.4 0.3 1.5 0.1 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC2A11 "GLUT10, GLUT11" ENSG00000133460 "Solute carrier family 2 member 11" Q9BYW1 22 23856703-23886309 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 298.2;Rod photoreceptor cells: 188.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SK-BR-3: 9.2" "Low region specificity" "Detected in all" "HPA042960, HPA071184" Uncertain Uncertain "Nucleoplasm,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions" Nucleoplasm "HPA042960: AB_2678241, HPA071184: AB_2686355" "unprognostic (1.31e-1)" "unprognostic (1.14e-1)" "unprognostic (3.69e-2)" "unprognostic (6.97e-2)" "unprognostic (7.93e-2)" "unprognostic (1.32e-1)" "unprognostic (4.24e-2)" "unprognostic (1.60e-3)" "unprognostic (3.53e-1)" "unprognostic (4.89e-2)" "prognostic favorable (3.83e-4)" "unprognostic (2.32e-1)" "prognostic favorable (5.77e-7)" "unprognostic (1.25e-1)" "unprognostic (1.70e-1)" "unprognostic (3.85e-1)" "unprognostic (6.29e-2)" 2.3 6.3 3.9 1.7 3.7 1.1 3.3 5.3 4.5 4.8 3.4 5.2 1.2 3.4 3.0 1.6 3.6 1.3 10.2 3.3 4.1 16.5 5.1 2.3 2.7 3.7 3.7 4.9 12.9 6.1 13.2 2.7 4.1 5.1 2.0 19.5 3.9 2.9 6.3 2.3 4.6 1.8 3.0 4.2 4.4 3.2 4.1 0.7 7.2 1.9 2.2 4.3 2.2 3.5 2.2 1.0 1.2 5.7 1.2 2.5 0.6 1.3 1.6 1.4 0.9 1.3 1.5 2.7 0.7 1.7 1.2 1.7 2.4 0.8 0.7 2.0 2.2 1.3 2.5 2.0 1.8 1.3 1.4 1.0 2.4 2.0 1.7 6.3 0.5 2.1 0.5 6.4 0.7 2.2 0.3 0.5 2.1 1.3 1.6 3.7 0.2 3.1 4.3 0.6 3.2 1.8 0.6 9.2 2.2 1.5 4.8 0.7 0.4 0.5 0.9 0.5 0.6 5.5 1.6 2.6 1.1 0.9 1.4 0.4 0.1 0.4 0.2 0.3 0.1 0.6 0.2 0.2 0.0 0.5 0.4 0.2 0.2 0.3 0.2 1.4 0.0 0.1 3.9 3.7 5.3 4.5 3.3 4.1 3.7 3.7 4.1 3.0 4.1 3.5 2.9 19.2 15.0 14.4 23.4 3.2 9.3 4.4 8.6 56.0 15.0 13.5 31.2 7.2 5.6 25.8 298.2 9.8 15.5 5.7 13.7 4.9 8.4 4.8 8.2 4.4 10.8 5.0 21.6 5.6 9.8 8.3 5.1 5.3 2.5 19.5 6.1 7.3 5.8 37.0 30.0 5.8 10.2 4.8 4.6 10.4 9.3 4.3 3.6 4.7 4.2 16.4 10.3 8.0 14.2 2.7 2.7 9.8 15.2 7.3 3.7 24.7 6.3 188.8 0.0 11.8 7.5 4.2 5.7 5.3 3.1 20.0 8.3 28.3 7.5 6.0 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 457.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "CACO-2: 7.7;Hep G2: 27.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860" "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.4 0.0 0.2 0.0 66.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.3 30.8 836.1 0.0 0.0 0.5 0.4 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 27.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.4 0.3 0.3 0.5 0.4 0.8 0.4 0.4 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 90.1 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 6.7 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 457.6 0.0 0.0 0.1 3.0 0.0 10.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 2.5 0.0 0.0 0.0 105.4 63.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.8 0.0 SLC2A3 GLUT3 ENSG00000059804 "Solute carrier family 2 member 3" P11169 12 7919230-7936187 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 427.9" "Cell type enhanced" "Detected in many" "Adipocytes: 362.1;Endothelial cells: 356.2;Extravillous trophoblasts: 382.4;granulocytes: 485.1;Langerhans cells: 710.4;Macrophages: 305.2;T-cells: 328.9" "Cancer enriched" "Detected in all" 7 "testis cancer: 107.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 166.1;neutrophil: 223.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 223.4" "Group enriched" "Detected in many" 5 "BEWO: 1473.1;CACO-2: 1646.2;SuSa: 1119.9" "CAB002763, HPA006539" Approved Approved "Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB002763: , HPA006539: AB_1078984" "unprognostic (9.20e-2)" "unprognostic (9.63e-3)" "prognostic unfavorable (8.58e-4)" "unprognostic (2.65e-1)" "unprognostic (5.29e-3)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (8.27e-2)" "unprognostic (2.35e-1)" "unprognostic (3.83e-2)" "unprognostic (8.47e-3)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.36e-8)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.70e-1)" "unprognostic (1.14e-2)" "unprognostic (2.91e-3)" 124.9 19.3 26.3 58.2 28.4 427.9 77.0 26.0 38.3 16.4 26.4 29.6 6.7 20.8 2.0 12.7 27.4 56.1 62.3 33.3 31.6 37.7 28.0 92.8 29.4 28.9 25.6 26.4 11.2 7.9 28.0 102.8 33.0 19.7 12.7 87.3 12.3 5.6 24.1 20.7 15.7 41.5 24.6 45.7 19.8 4.9 31.1 18.4 43.3 10.0 20.8 98.7 26.2 23.3 0.3 7.9 68.5 27.4 25.2 85.9 1473.1 24.7 26.7 23.9 55.9 1646.2 11.0 1.6 0.0 17.1 33.1 0.6 2.4 3.9 43.0 48.4 2.0 96.3 6.5 219.3 67.3 35.0 135.4 36.2 2.8 63.6 28.5 55.8 22.6 7.5 44.8 22.8 21.9 0.1 2.6 38.4 300.9 1.2 0.0 2.1 8.0 1.4 0.1 0.1 0.3 0.6 0.0 2.4 32.8 1119.9 0.0 4.9 23.1 29.7 15.6 57.4 2.5 0.2 68.8 5.2 86.9 15.9 16.6 166.1 19.3 29.7 25.3 2.3 20.2 7.4 16.9 19.5 10.0 7.0 10.8 14.8 223.4 15.6 1.0 0.8 24.9 17.4 26.3 28.4 26.0 38.3 33.3 31.6 28.9 25.6 33.0 24.6 31.1 23.3 362.1 144.2 98.8 5.5 301.0 129.5 3.5 1.7 8.6 33.0 5.1 7.6 21.0 7.2 26.8 3.7 62.6 69.6 112.1 0.2 0.0 0.2 3.1 5.0 84.3 356.2 1.2 13.7 24.4 0.0 382.4 188.9 12.2 4.3 485.1 6.5 96.4 2.4 113.4 5.0 20.8 0.3 0.0 76.4 710.4 3.1 10.2 305.2 183.2 34.7 43.4 28.5 41.2 6.6 5.0 0.7 1.3 7.9 93.2 5.3 0.1 1.4 10.3 70.2 118.3 21.5 187.1 2.4 1.2 4.9 82.0 111.4 328.9 41.7 0.1 4.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" 14.8 18.0 15.7 10.9 17.0 29.8 8.5 15.2 19.3 18.6 27.8 15.4 28.2 10.8 9.9 8.0 12.5 12.4 10.0 16.9 15.4 20.5 86.1 7.2 6.1 17.9 17.3 7.8 11.3 10.3 4.6 10.1 16.8 7.8 13.6 6.1 9.3 7.9 1.8 16.0 19.9 11.6 16.7 15.4 9.5 13.4 18.9 4.5 16.9 4.8 7.1 12.2 7.5 13.2 10.3 15.0 7.7 9.9 32.4 14.9 70.5 27.3 19.3 13.8 13.6 6.4 46.6 5.8 24.1 24.4 19.3 17.2 11.5 15.4 16.4 15.0 9.3 4.7 28.8 14.7 18.1 15.8 10.0 22.5 37.5 17.7 28.4 20.5 8.6 3.4 18.7 25.5 17.2 9.1 3.2 9.9 24.2 10.6 12.0 10.0 3.7 20.4 42.5 26.4 7.8 13.7 26.7 13.6 62.7 14.2 7.0 20.2 14.6 10.4 24.8 35.4 22.1 11.9 19.0 4.5 9.8 15.7 9.3 1.4 1.3 0.5 0.4 1.5 0.5 0.2 0.3 0.2 0.9 0.1 0.3 0.4 0.1 0.4 1.2 0.5 0.3 0.4 15.7 17.0 15.2 19.3 16.9 15.4 17.9 17.3 16.8 16.7 18.9 13.2 29.7 9.6 9.8 3.9 8.8 28.6 8.2 3.0 16.5 11.0 24.9 14.7 21.0 18.6 4.2 36.8 6.2 11.6 19.9 54.5 1.9 6.9 44.0 37.0 19.1 27.3 9.5 26.1 0.6 12.5 32.7 15.9 8.6 66.4 5.1 7.5 17.9 94.9 32.0 6.7 0.6 22.8 2.0 27.2 14.5 6.8 9.9 25.5 21.4 3.7 18.8 29.0 1.0 1.0 0.1 9.5 41.7 7.5 8.6 13.9 49.2 29.8 6.4 9.4 6.6 15.9 11.7 37.9 17.4 24.2 46.2 24.5 14.2 14.8 23.3 13.7 SLC31A2 "COPT2, CTR2, hCTR2" ENSG00000136867 "Solute carrier family 31 member 2" O15432 9 113150976-113164140 "Predicted membrane proteins, Transporters" "Copper transport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "parathyroid gland: 571.4;salivary gland: 409.1" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 96.4;Kupffer cells: 145.6;Macrophages: 101.3;monocytes: 84.1;Oligodendrocytes: 113.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 12 "classical monocyte: 226.0;intermediate monocyte: 331.9;myeloid DC: 134.6;neutrophil: 355.8;non-classical monocyte: 423.3" "Group enriched" "Detected in all" 47 "dendritic cells: 134.6;granulocytes: 355.8;monocytes: 423.3" "Cell line enhanced" "Detected in many" "ASC diff: 54.4;hTCEpi: 85.0;hTERT-HME1: 57.7;LHCN-M2: 68.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014861 Approved Approved "Nuclear speckles,Plasma membrane,Intermediate filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 30: Epithelial cell lines - Translation" "Cluster 41: Macrophages - Immune response" "Nuclear speckles" "Plasma membrane, Intermediate filaments" "HPA014861: AB_1857098" "unprognostic (2.26e-1)" "unprognostic (7.20e-2)" "unprognostic (3.79e-3)" "unprognostic (1.09e-1)" "unprognostic (1.10e-1)" "unprognostic (4.81e-3)" "unprognostic (5.63e-2)" "unprognostic (3.31e-2)" "unprognostic (2.24e-1)" "unprognostic (3.44e-2)" "unprognostic (1.47e-1)" "unprognostic (1.86e-1)" "unprognostic (6.05e-3)" "unprognostic (1.76e-1)" "unprognostic (3.56e-2)" "unprognostic (1.25e-1)" "unprognostic (8.89e-2)" 48.2 16.7 45.0 18.4 72.6 20.1 24.4 68.2 77.8 7.3 34.2 11.3 10.8 4.4 16.7 9.3 6.9 8.6 10.3 45.1 54.0 27.8 33.4 27.4 16.1 76.6 65.8 5.1 19.2 571.4 2.5 23.6 71.4 4.4 12.1 0.8 409.1 42.6 16.7 48.2 17.2 10.8 61.5 32.7 11.8 13.8 61.7 12.1 6.3 14.6 17.6 13.3 10.7 108.2 7.8 3.1 1.3 1.7 54.4 22.3 6.5 4.0 13.9 12.8 12.3 2.4 1.5 0.3 0.5 9.1 7.9 37.7 5.1 31.0 12.0 2.2 1.3 0.1 1.2 3.3 20.7 1.9 0.8 25.3 85.0 30.0 57.7 1.8 6.9 3.0 1.4 2.6 68.9 6.5 1.6 0.7 0.4 1.8 2.6 0.2 39.3 0.0 4.5 4.2 0.9 2.5 6.9 36.4 1.4 0.8 8.6 2.5 2.4 2.0 1.9 13.7 3.2 2.1 5.0 0.1 12.5 3.2 2.0 5.1 226.0 24.0 4.3 331.9 6.5 1.2 4.9 5.2 134.6 1.0 3.8 3.9 355.8 1.0 423.3 2.1 3.0 104.9 45.0 72.6 68.2 77.8 45.1 54.0 76.6 65.8 71.4 61.5 61.7 108.2 13.8 9.6 9.2 2.3 7.0 37.1 6.4 37.7 13.6 7.0 15.3 10.8 0.6 4.3 10.9 1.8 35.5 96.4 3.6 12.8 3.9 13.5 4.1 23.5 4.9 6.4 3.5 0.4 2.1 7.7 9.0 14.4 3.6 8.4 0.0 2.7 12.8 18.1 57.2 6.7 1.8 4.5 10.2 145.6 65.6 4.6 15.8 101.3 0.0 4.7 84.1 6.9 3.1 0.5 113.7 18.5 11.0 9.4 9.1 10.2 51.3 18.2 14.8 9.1 19.7 8.7 7.8 31.0 5.2 3.3 38.4 43.1 7.9 4.6 5.7 7.6 SLC34A1 "NAPI-3, NPT2, NPTIIa, SLC11, SLC17A2" ENSG00000131183 "Solute carrier family 34 member 1" Q06495 5 177379235-177398848 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 54 "kidney: 155.4" "Cell type enriched" "Detected in some" 14 "Proximal tubular cells: 143.2" "Cancer enriched" "Detected in single" 12 "renal cancer: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "HEL: 2.4;U-937: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA051255, HPA077175" Approved Approved "Nucleoplasm,Nuclear speckles,Plasma membrane,Mitotic spindle,Cytosol" Yes NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nuclear speckles, Plasma membrane" "Nucleoplasm, Mitotic spindle, Cytosol" "HPA051255: AB_2681409, HPA077175: " "unprognostic (1.17e-1)" "unprognostic (3.33e-3)" "unprognostic (1.49e-1)" "unprognostic (3.49e-2)" "unprognostic (1.56e-3)" "unprognostic (2.28e-1)" "unprognostic (4.50e-2)" "unprognostic (4.43e-3)" "unprognostic (1.91e-1)" "unprognostic (1.14e-1)" "unprognostic (5.95e-2)" "unprognostic (1.23e-3)" "unprognostic (1.38e-1)" "unprognostic (2.01e-1)" "unprognostic (1.28e-2)" "unprognostic (4.66e-2)" 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 155.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 7.3 0.0 0.0 0.2 0.0 9.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 143.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 0.0 0.1 SLC34A2 NAPI-3B ENSG00000157765 "Solute carrier family 34 member 2" O95436 4 25648011-25678748 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "lung: 753.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 477.5;Alveolar cells type 2: 1315.9;Club cells: 179.9;Glandular and luminal cells: 241.3;Respiratory ciliated cells: 217.0" "Group enriched" "Detected in many" 4 "lung cancer: 252.6;ovarian cancer: 191.7;thyroid cancer: 585.2" "Region enriched" "Detected in single" 6 "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 82 "BEWO: 32.2;EFO-21: 121.0;RPTEC TERT1: 86.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA037989, HPA066474" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 19: Lung - Lung function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA037989: AB_10670536, HPA066474: " "unprognostic (1.60e-2)" "unprognostic (1.12e-1)" "unprognostic (1.38e-1)" "unprognostic (4.25e-2)" "unprognostic (7.33e-2)" "unprognostic (9.83e-2)" "unprognostic (2.37e-2)" "unprognostic (6.60e-3)" "unprognostic (6.27e-2)" "unprognostic (1.89e-2)" "unprognostic (5.77e-2)" "unprognostic (2.24e-1)" "unprognostic (7.08e-3)" "unprognostic (3.25e-1)" "unprognostic (6.75e-2)" "unprognostic (2.57e-2)" "unprognostic (1.93e-1)" 0.4 0.8 0.0 0.3 0.0 0.0 19.1 2.1 0.2 66.6 6.9 0.1 16.4 34.6 0.1 1.5 69.8 9.0 0.2 0.1 0.0 16.7 1.2 753.0 0.1 0.0 0.0 1.3 7.3 0.0 2.1 4.8 0.1 1.0 0.0 0.5 90.2 16.8 0.1 2.6 4.3 0.2 0.0 0.7 2.5 2.7 0.3 2.1 33.6 0.0 7.4 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 32.2 0.0 0.0 0.0 0.0 0.2 0.1 0.2 121.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.1 0.0 0.2 0.1 0.1 86.8 0.0 0.1 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.7 0.9 0.0 0.5 0.4 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.2 477.5 1315.9 0.0 0.1 0.0 0.1 79.1 0.0 0.0 41.5 7.5 0.8 34.3 179.9 20.2 0.0 1.4 0.0 0.0 5.9 72.2 5.4 78.6 30.3 2.5 0.0 0.0 0.1 8.5 0.0 2.6 0.0 241.3 29.0 0.0 0.0 0.0 0.2 0.0 0.1 1.2 26.4 0.0 0.0 20.8 1.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.8 2.5 0.0 0.0 11.8 13.6 3.4 217.0 0.0 0.0 0.0 5.8 2.1 0.1 0.0 0.0 0.3 4.8 0.0 1.8 4.0 SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA034828: AB_2674350, HPA049229: AB_2680682" "unprognostic (1.59e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (8.37e-2)" "unprognostic (3.87e-3)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (4.83e-2)" 9.8 22.8 4.6 6.0 5.9 8.0 14.3 12.0 6.6 9.3 31.5 14.7 13.7 10.3 11.5 11.1 8.0 11.1 11.0 6.1 6.4 18.0 14.6 9.9 9.0 6.7 4.8 12.4 15.1 17.4 5.2 11.1 7.1 11.2 13.6 14.1 9.8 6.9 12.3 20.3 12.9 8.9 5.4 10.1 12.9 7.1 5.2 5.7 23.7 11.2 10.0 8.0 6.3 12.0 9.7 9.6 7.7 4.9 48.6 36.8 14.0 15.9 13.2 7.7 12.9 24.3 18.9 18.5 22.1 21.9 21.3 8.7 12.2 12.5 17.9 5.7 4.9 9.7 9.6 19.7 20.8 12.8 24.0 46.8 17.4 17.9 25.9 22.1 15.2 4.6 7.7 11.2 19.1 8.5 5.6 14.0 3.6 15.0 5.2 6.5 13.1 9.7 52.5 15.8 2.1 6.0 12.9 14.5 11.5 12.8 9.4 12.6 12.7 14.3 6.3 9.2 6.7 9.7 8.7 8.2 16.8 8.9 13.6 2.9 0.7 0.6 0.5 0.8 0.6 0.9 0.5 0.4 0.6 1.2 0.6 0.6 2.1 1.0 1.2 0.9 0.9 0.6 4.6 5.9 12.0 6.6 6.1 6.4 6.7 4.8 7.1 5.4 5.2 12.0 18.9 22.4 19.8 39.5 18.0 25.4 31.1 20.0 31.9 10.3 20.4 9.8 25.4 21.5 30.4 73.5 22.9 46.3 11.6 44.1 11.7 28.7 28.3 32.4 21.9 15.4 14.5 9.9 43.4 28.5 72.0 24.8 28.5 38.6 24.1 14.4 12.5 20.8 28.3 5.0 47.0 25.6 12.2 13.4 17.2 15.6 12.5 14.6 8.8 39.4 15.5 21.0 7.2 65.4 83.2 23.1 29.7 13.9 37.5 35.3 47.9 45.1 26.3 19.6 0.0 14.2 22.7 60.0 20.5 32.7 34.0 66.4 10.8 41.0 24.8 35.1 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC36A4 "FLJ38932, PAT4" ENSG00000180773 "Solute carrier family 36 member 4" Q6YBV0 11 93144174-93197991 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017887 Enhanced Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 34: Non-specific - Transcription" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Golgi apparatus, Plasma membrane, Cytosol" "HPA017887: AB_2190238" "unprognostic (1.23e-2)" "unprognostic (1.08e-1)" "unprognostic (2.17e-3)" "unprognostic (1.32e-3)" "unprognostic (3.66e-2)" "unprognostic (8.77e-2)" "unprognostic (1.08e-3)" "unprognostic (7.83e-3)" "unprognostic (3.06e-2)" "unprognostic (7.97e-2)" "unprognostic (2.09e-2)" "unprognostic (8.04e-3)" "unprognostic (7.07e-2)" "unprognostic (4.40e-2)" "unprognostic (1.74e-1)" "unprognostic (9.45e-3)" "unprognostic (4.20e-2)" 5.8 7.4 4.2 9.3 4.6 19.4 4.6 8.1 5.8 5.1 6.2 5.4 2.0 7.1 2.1 5.3 4.8 5.7 6.0 4.0 8.5 9.4 7.8 6.0 5.3 7.2 6.9 5.7 5.7 6.5 7.7 6.2 7.7 4.9 6.4 15.3 3.7 5.9 2.4 4.1 3.1 8.1 5.5 4.1 4.3 4.3 6.1 7.3 8.8 2.3 6.7 6.9 3.6 7.0 10.4 18.2 36.5 7.3 12.7 25.6 20.5 17.6 29.2 25.6 31.0 14.6 33.1 12.5 9.9 16.5 13.3 12.5 11.4 6.5 23.4 21.1 13.3 14.5 35.3 9.8 10.0 36.6 20.6 12.4 20.0 14.9 9.2 12.0 14.0 17.6 1.3 0.2 26.5 2.6 16.3 27.4 14.8 4.0 18.4 7.2 21.7 5.1 8.7 15.1 33.6 43.8 25.7 9.9 6.4 26.4 18.0 10.6 15.7 48.0 14.8 28.6 26.0 5.1 10.9 0.0 10.9 15.0 25.4 0.1 4.9 5.3 0.8 2.6 1.0 0.9 0.6 1.0 1.9 1.0 1.5 1.0 1.5 0.5 1.7 0.7 0.5 1.1 4.2 4.6 8.1 5.8 4.0 8.5 7.2 6.9 7.7 5.5 6.1 7.0 11.9 12.8 11.5 35.9 29.5 30.7 43.2 9.7 25.6 21.2 10.3 8.0 11.5 20.0 7.1 20.2 22.9 10.7 13.6 3.1 35.2 24.4 9.9 15.5 19.2 18.5 27.6 5.5 66.8 43.6 25.8 21.9 18.8 5.7 4.5 29.0 13.2 9.1 13.6 26.9 71.0 19.6 10.2 52.3 47.1 4.2 18.0 50.1 21.4 27.2 42.8 20.7 13.4 45.2 59.4 33.2 6.3 15.4 22.1 70.4 0.4 16.2 20.8 24.2 6.6 18.0 18.1 7.3 3.3 11.8 32.0 16.3 15.7 20.6 4.3 30.6 SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1118.3;Suprabasal keratinocytes: 1078.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 1198.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" 112.8 113.0 36.1 71.6 48.5 95.4 88.5 53.9 50.2 91.7 25.8 58.3 33.6 92.9 38.6 108.1 83.6 131.3 60.7 32.4 46.1 64.8 307.3 117.0 67.1 52.2 42.7 130.1 74.7 91.5 27.9 162.1 53.5 52.8 49.7 27.0 77.2 43.1 108.5 204.4 54.4 115.8 44.2 75.3 63.0 25.4 44.2 100.4 63.1 174.7 78.1 98.9 88.0 73.0 83.7 179.9 157.6 444.1 356.7 347.7 118.1 382.8 921.2 313.0 254.0 108.2 151.2 0.1 504.2 627.9 215.3 271.1 107.9 335.1 299.1 67.0 61.0 105.8 208.7 339.9 548.8 88.0 108.7 357.2 718.4 199.5 1198.9 778.5 265.7 116.3 103.8 163.1 560.4 100.0 110.3 122.8 138.2 0.1 185.1 97.5 115.5 200.9 191.6 173.4 103.9 89.8 263.5 68.5 233.7 171.0 140.5 193.8 467.3 156.7 121.8 67.8 62.2 187.8 194.3 100.6 148.0 304.5 76.8 41.1 24.9 18.9 22.7 13.1 17.4 19.2 19.0 23.0 35.2 17.8 23.5 24.8 17.5 51.6 18.4 40.6 23.7 27.6 36.1 48.5 53.9 50.2 32.4 46.1 52.2 42.7 53.5 44.2 44.2 73.0 237.7 83.3 77.4 31.3 187.7 1118.3 134.1 262.8 653.9 40.5 315.7 252.2 153.6 108.7 123.9 57.0 70.9 53.8 292.3 114.6 5.9 41.2 5.5 228.5 245.0 234.7 76.7 109.0 54.6 51.1 49.3 219.1 328.2 464.0 81.6 138.3 227.7 265.9 54.0 53.8 58.9 175.0 130.2 143.3 303.6 12.4 263.2 193.8 250.8 59.0 52.6 74.3 70.0 42.3 136.2 79.4 83.5 85.0 322.2 181.7 67.4 24.4 50.3 68.7 282.7 184.8 339.5 6.7 15.5 532.6 1078.3 38.4 252.4 84.0 110.7 150.8 SLC38A5 "JM24, SN2" ENSG00000017483 "Solute carrier family 38 member 5" Q8WUX1 X 48458537-48470260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "pancreas: 237.2" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 196.3;Erythroid cells: 74.3;Exocrine glandular cells: 80.8;Pancreatic endocrine cells: 129.4;Plasma cells: 62.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 214.0;HBEC3-KT: 326.7;HeLa: 300.0;hTCEpi: 237.8;Karpas-707: 282.8;RPMI-8226: 539.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047411 Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" Cytosol "HPA047411: AB_10964355" "unprognostic (2.81e-1)" "unprognostic (4.87e-2)" "unprognostic (7.92e-3)" "unprognostic (1.58e-1)" "unprognostic (1.29e-3)" "unprognostic (1.26e-1)" "unprognostic (7.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.52e-1)" "unprognostic (3.80e-3)" "prognostic unfavorable (2.13e-4)" "unprognostic (2.99e-2)" "prognostic unfavorable (2.22e-16)" "unprognostic (1.27e-3)" "unprognostic (1.45e-1)" "unprognostic (2.86e-1)" "unprognostic (2.20e-1)" 4.2 1.9 29.9 13.0 21.8 55.7 2.5 22.6 26.3 9.4 10.6 13.2 13.3 4.2 2.7 10.2 4.9 3.7 6.1 21.6 22.5 1.8 0.9 25.3 8.8 30.4 23.1 6.7 237.2 0.4 0.9 1.1 28.0 5.6 16.2 3.4 9.3 8.6 0.6 21.3 9.2 7.0 22.0 13.8 15.9 0.7 30.4 8.5 20.3 1.3 9.1 9.4 8.7 21.1 143.0 0.3 0.1 1.6 2.8 11.6 0.3 9.4 0.0 0.3 0.1 0.4 0.3 147.8 0.2 61.7 0.3 214.0 164.4 326.7 0.0 47.4 0.2 80.7 300.0 102.4 23.2 166.7 0.2 22.0 237.8 2.9 0.6 0.2 2.8 35.5 150.7 282.8 32.2 0.2 36.3 57.9 74.2 0.0 0.7 131.5 0.7 539.6 0.0 0.1 13.1 0.7 0.1 0.9 0.2 1.1 0.5 6.9 4.7 0.6 0.4 0.4 0.4 0.4 1.0 53.0 1.6 0.8 0.7 0.1 0.4 0.4 17.3 0.6 24.2 11.4 18.6 16.4 2.3 8.9 8.7 11.3 0.5 9.6 0.1 13.1 21.7 9.1 29.9 21.8 22.6 26.3 21.6 22.5 30.4 23.1 28.0 22.0 30.4 21.1 2.3 0.0 0.6 0.3 15.4 26.6 2.7 196.3 17.1 3.2 0.2 0.3 0.4 0.0 33.6 5.5 18.8 0.2 6.7 9.9 0.0 5.5 0.4 1.1 9.1 11.8 0.0 74.3 0.3 80.8 0.6 8.9 3.6 2.7 4.5 1.0 0.4 0.4 2.4 0.0 0.5 17.5 4.1 0.3 3.9 1.3 2.5 2.1 8.8 32.8 1.8 0.3 8.2 0.5 0.2 129.4 5.5 1.2 62.3 4.5 1.2 0.0 4.2 0.3 0.0 0.7 4.6 0.1 0.4 6.4 8.5 0.0 9.5 4.6 21.4 1.9 SLC38A6 NAT-1 ENSG00000139974 "Solute carrier family 38 member 6" Q8IZM9 14 60981114-61083733 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 178.2;Excitatory neurons: 98.8;Hofbauer cells: 100.3;Inhibitory neurons: 77.4;Late spermatids: 124.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "ASC diff: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018508 Approved Approved "Plasma membrane,Cell Junctions,Microtubules" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Plasma membrane, Microtubules" "HPA018508: AB_2190518" "unprognostic (7.08e-2)" "unprognostic (4.14e-2)" "unprognostic (1.75e-1)" "unprognostic (3.49e-1)" "unprognostic (1.00e-1)" "unprognostic (1.74e-2)" "prognostic unfavorable (9.47e-6)" "unprognostic (9.89e-3)" "unprognostic (2.38e-1)" "unprognostic (2.18e-2)" "unprognostic (2.20e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (1.37e-5)" "unprognostic (1.73e-1)" "unprognostic (4.63e-2)" "unprognostic (1.47e-1)" "unprognostic (2.90e-1)" 7.6 9.1 6.0 4.7 6.6 2.9 7.4 6.1 9.5 7.3 8.9 4.8 3.1 5.1 13.2 3.3 5.6 9.9 3.7 6.9 6.5 12.0 6.3 8.6 7.8 5.4 6.0 5.8 3.4 21.3 7.2 9.6 6.0 5.1 6.6 7.5 5.9 3.9 2.1 2.9 3.5 5.3 5.0 6.6 3.8 5.0 7.4 5.0 6.3 3.0 4.8 7.0 5.0 6.7 16.2 21.5 6.8 12.3 68.7 25.3 4.9 11.6 34.5 10.7 10.2 5.4 41.0 4.0 19.2 10.6 22.5 13.5 6.8 11.9 9.8 6.0 3.2 6.7 8.6 14.2 22.7 3.7 12.1 19.9 4.9 10.5 12.2 43.2 14.3 6.8 9.3 8.4 37.5 9.2 6.6 8.4 4.0 9.5 14.3 1.6 20.1 11.9 30.7 8.5 3.3 3.0 9.9 7.0 19.1 9.3 10.4 5.8 15.6 16.4 7.1 20.0 6.5 1.6 4.9 1.6 34.0 3.0 13.1 0.0 6.6 0.1 1.7 7.1 2.2 2.2 3.1 2.4 3.6 2.0 2.7 3.4 0.2 0.8 4.5 4.4 4.5 2.8 6.0 6.6 6.1 9.5 6.9 6.5 5.4 6.0 6.0 5.0 7.4 6.7 6.8 22.4 6.7 31.6 6.0 5.2 11.4 14.6 8.0 19.7 7.2 7.5 4.3 7.2 10.0 5.5 22.9 5.6 4.9 2.6 1.9 5.3 178.2 13.0 11.0 7.2 4.2 3.4 98.8 2.8 9.4 11.2 5.1 6.2 6.3 7.3 4.2 4.6 100.3 5.0 77.4 3.1 6.1 24.8 10.0 124.4 10.8 26.2 5.4 20.6 6.4 11.7 2.1 54.3 30.8 7.4 1.9 6.0 5.8 6.6 3.3 23.1 40.4 24.9 0.0 12.3 9.1 16.6 11.5 6.4 2.8 6.7 7.8 5.0 2.8 6.9 SLC38A7 FLJ10815 ENSG00000103042 "Solute carrier family 38 member 7" Q9NVC3 16 58665109-58684770 "Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 32.8" "Group enriched" "Detected in all" 13 "Early spermatids: 271.8;Late spermatids: 753.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041777, HPA049428" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA041777: AB_10796782, HPA049428: " "unprognostic (2.16e-3)" "unprognostic (2.30e-2)" "unprognostic (6.23e-3)" "prognostic favorable (6.87e-4)" "unprognostic (3.49e-1)" "unprognostic (8.08e-3)" "unprognostic (9.76e-3)" "unprognostic (6.34e-3)" "unprognostic (1.98e-2)" "unprognostic (2.02e-1)" "unprognostic (2.77e-1)" "unprognostic (4.90e-2)" "prognostic favorable (2.87e-4)" "unprognostic (1.85e-1)" "unprognostic (4.38e-2)" "unprognostic (7.50e-2)" "unprognostic (4.93e-3)" 6.0 11.4 7.5 6.0 7.8 2.6 5.3 6.0 8.9 5.1 6.1 5.1 4.3 5.5 6.2 6.5 4.0 5.6 15.9 7.9 7.4 7.3 13.6 5.4 4.3 7.7 7.6 4.6 4.8 14.1 7.2 7.5 8.1 5.5 5.9 4.7 6.2 4.6 9.4 5.3 5.5 7.4 5.8 10.3 5.4 32.8 9.8 3.6 7.8 8.3 4.6 5.4 4.9 7.0 6.9 10.9 10.8 16.5 22.0 12.9 19.3 16.2 18.7 22.7 15.6 9.9 11.0 4.5 8.9 22.9 17.9 15.9 10.2 11.7 13.3 2.8 9.4 5.1 9.3 16.5 32.9 10.6 14.0 25.9 23.6 16.1 10.3 12.3 23.5 10.4 14.9 6.3 16.7 8.0 4.3 6.3 11.7 7.5 16.0 15.2 11.6 12.1 10.0 15.4 7.9 11.3 25.7 17.0 7.0 14.4 7.6 4.2 18.7 12.3 9.3 21.8 5.0 9.7 6.7 5.2 16.8 6.3 9.3 0.1 6.8 2.0 4.0 6.6 2.2 1.3 2.4 2.9 4.5 2.5 1.9 2.1 0.5 1.8 6.4 1.7 1.8 5.5 7.5 7.8 6.0 8.9 7.9 7.4 7.7 7.6 8.1 5.8 9.8 7.0 3.3 3.2 4.4 7.8 2.0 3.8 4.0 4.4 1.2 9.8 4.7 3.2 12.8 4.3 4.8 11.0 12.5 8.4 5.0 3.7 3.9 14.0 271.8 3.5 6.8 6.2 13.1 2.1 13.3 8.5 9.5 5.1 9.7 6.0 1.3 10.7 8.2 9.3 38.6 16.8 15.5 3.1 12.2 10.1 8.2 753.3 9.6 11.6 8.8 9.4 4.0 7.1 8.2 5.0 7.6 12.8 2.7 8.6 1.8 3.7 4.8 5.9 3.8 7.1 6.6 4.8 5.1 6.9 7.6 4.6 4.3 15.3 2.7 8.6 4.9 3.2 SLC39A10 "DKFZp564L2123, FLJ90515, KIAA1265" ENSG00000196950 "Solute carrier family 39 member 10" Q9ULF5 2 195575977-195737702 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 48.4" "Cell type enhanced" "Detected in all" "Excitatory neurons: 170.8;Microglial cells: 362.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036512, HPA036513, HPA066087" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 250000 "Cluster 6: Non-specific - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA036512: AB_2675165, HPA036513: AB_10670801, HPA066087: AB_2685613" "unprognostic (1.06e-1)" "unprognostic (3.87e-3)" "unprognostic (5.33e-2)" "unprognostic (1.33e-3)" "prognostic favorable (1.46e-5)" "unprognostic (7.40e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (2.10e-2)" "unprognostic (8.73e-2)" "unprognostic (2.84e-2)" "prognostic unfavorable (3.23e-4)" "unprognostic (8.46e-2)" "unprognostic (9.71e-2)" "unprognostic (1.34e-2)" "unprognostic (3.68e-1)" "unprognostic (2.47e-2)" "unprognostic (6.89e-2)" 8.2 9.7 7.9 6.3 7.4 4.6 7.1 0.0 21.0 10.8 0.0 4.3 3.9 11.0 3.7 3.6 9.5 8.8 4.3 15.8 0.0 8.7 2.0 7.4 8.3 0.1 0.4 7.9 4.8 5.2 1.1 12.8 1.7 19.1 4.2 5.1 3.7 6.7 1.3 7.0 4.0 7.7 1.4 18.3 5.0 9.3 9.9 10.6 48.4 3.1 7.6 6.3 2.1 5.8 7.3 27.1 46.8 13.0 9.5 21.1 24.3 34.8 16.4 16.1 8.1 38.4 26.4 10.4 51.3 19.6 12.4 10.4 28.6 31.6 19.9 5.4 21.8 11.7 37.1 34.0 10.8 45.4 4.9 12.9 5.1 17.7 20.2 56.9 37.3 10.5 34.9 14.3 26.7 7.3 12.7 14.0 53.8 44.1 18.8 28.9 16.6 27.0 74.8 12.7 17.5 24.7 34.4 65.1 18.7 81.2 11.2 26.5 36.1 28.7 33.6 19.0 18.7 4.6 3.7 6.3 24.5 19.9 29.9 41.5 4.7 3.7 7.5 4.4 6.1 12.3 6.8 6.7 6.4 15.8 6.0 7.8 0.8 21.7 3.3 32.8 7.6 2.6 7.9 7.4 0.0 21.0 15.8 0.0 0.1 0.4 1.7 1.4 9.9 5.8 72.1 3.2 12.8 40.8 42.0 25.6 12.1 51.3 13.1 23.0 16.9 23.1 7.6 5.7 33.2 36.8 8.4 49.3 60.2 4.3 1.9 17.7 28.5 13.2 48.7 75.4 15.6 26.9 170.8 11.3 66.0 35.3 11.2 16.5 13.3 25.7 26.4 2.8 24.5 8.4 78.3 5.9 26.4 20.7 27.1 16.0 19.0 31.8 7.2 362.6 16.2 17.0 20.6 49.3 49.5 24.3 2.8 18.8 21.3 20.1 4.5 14.7 9.5 20.0 13.1 41.9 29.1 61.3 33.6 7.5 20.5 23.4 35.4 30.8 6.2 7.8 SLC39A14 "KIAA0062, NET34, ZIP14" ENSG00000104635 "Solute carrier family 39 member 14" Q15043 8 22367278-22434129 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Disease variant, Dystonia, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 551.3;pancreas: 252.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 266.7;Hepatocytes: 611.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 321.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016508, HPA056732" Enhanced Approved "Endoplasmic reticulum,Golgi apparatus,Plasma membrane" NA NA 1100000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 85: Liver - Metabolism" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Golgi apparatus, Plasma membrane" "HPA016508: AB_1857148, HPA056732: " "unprognostic (1.67e-1)" "unprognostic (6.67e-3)" "prognostic favorable (5.00e-5)" "unprognostic (9.83e-3)" "unprognostic (9.21e-3)" "unprognostic (8.99e-3)" "unprognostic (1.99e-1)" "unprognostic (2.91e-2)" "unprognostic (4.95e-2)" "unprognostic (5.66e-2)" "unprognostic (6.64e-2)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.79e-7)" "unprognostic (4.88e-2)" "unprognostic (8.73e-2)" "unprognostic (1.63e-2)" "unprognostic (1.11e-3)" 63.5 72.4 13.0 35.5 11.0 1.4 39.8 11.9 13.1 17.3 39.7 48.2 142.2 30.2 6.2 11.6 25.9 32.0 76.7 14.5 22.9 30.8 551.3 23.9 7.6 43.0 30.4 27.7 252.7 12.9 21.5 19.0 25.7 22.3 50.3 18.6 21.8 18.7 43.0 20.0 84.9 33.0 13.3 8.1 80.5 26.5 25.3 6.0 87.7 17.4 6.9 56.0 14.5 14.8 51.8 68.3 18.4 37.6 65.1 54.7 40.1 72.8 321.0 111.3 173.5 226.9 47.9 51.1 39.9 86.1 288.9 55.6 92.8 91.1 181.9 53.1 49.2 40.8 51.0 230.7 154.3 28.5 43.2 58.4 72.6 198.0 136.9 56.3 50.5 36.5 36.2 51.2 57.3 24.0 43.4 18.2 113.4 81.9 49.8 60.1 34.9 110.8 40.8 22.3 31.3 48.7 74.3 31.3 151.4 39.7 25.1 39.4 28.0 137.3 69.2 87.4 75.7 29.2 28.7 66.9 194.3 37.7 81.9 0.0 0.4 2.1 6.7 0.1 7.2 4.0 3.8 5.0 1.5 1.9 4.3 5.9 0.1 2.7 0.1 0.7 3.4 3.4 13.0 11.0 11.9 13.1 14.5 22.9 43.0 30.4 25.7 13.3 25.3 14.8 12.4 3.2 7.7 11.4 9.1 33.3 11.5 10.8 18.8 7.8 20.3 16.6 66.6 41.5 3.8 7.3 2.1 0.4 3.6 91.6 1.9 47.6 0.5 136.1 58.3 32.2 33.4 10.5 26.2 74.7 2.7 58.8 47.9 266.7 0.0 20.8 29.6 611.4 1.8 48.8 24.6 60.6 6.1 15.4 25.8 3.2 23.9 2.9 44.4 6.5 2.7 5.2 2.1 9.0 3.9 47.3 39.1 41.8 13.5 26.5 75.6 24.6 1.1 8.2 0.0 47.1 32.2 0.7 3.0 4.1 21.0 0.5 7.4 14.7 43.5 9.4 SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;seminal vesicle: 33.2;skin 1: 37.5" "Cell type enhanced" "Detected in some" "Muller glia cells: 22.3;Squamous epithelial cells: 12.0;Suprabasal keratinocytes: 6.0;Urothelial cells: 4.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 71 "HaCaT: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" 0.1 0.0 0.2 0.1 0.2 0.0 1.9 0.3 0.3 8.0 0.2 1.9 0.0 0.3 0.1 18.8 0.5 0.4 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.3 0.1 0.3 0.2 12.2 1.3 3.7 4.1 33.2 0.2 37.5 0.1 0.2 0.3 0.0 0.0 0.1 0.3 2.8 0.0 0.0 2.7 0.3 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 0.0 0.2 0.8 0.3 0.4 0.0 0.7 0.0 2.1 0.1 0.0 0.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 12.0 6.0 0.3 0.0 0.0 1.4 4.4 SLC39A6 LIV-1 ENSG00000141424 "Solute carrier family 39 member 6" Q13433 18 36108531-36129385 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Breast glandular cells: 307.0;Prostatic glandular cells: 197.9" "Group enriched" "Detected in all" 4 "breast cancer: 361.9;prostate cancer: 127.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042377 Approved Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 35: Glandular cells - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA042377: AB_2677968" "unprognostic (7.60e-2)" "unprognostic (2.27e-2)" "unprognostic (5.50e-3)" "unprognostic (2.58e-3)" "unprognostic (1.02e-1)" "unprognostic (4.87e-3)" "prognostic unfavorable (5.33e-4)" "unprognostic (1.79e-1)" "unprognostic (2.00e-1)" "unprognostic (1.18e-1)" "unprognostic (3.19e-1)" "unprognostic (4.50e-2)" "unprognostic (7.63e-3)" "unprognostic (2.16e-1)" "unprognostic (4.74e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" 27.3 25.9 23.3 21.6 28.5 11.6 147.2 28.6 26.1 34.5 48.9 13.9 9.6 56.9 56.2 17.0 63.6 24.2 14.0 20.0 28.8 28.2 16.5 18.9 17.3 28.8 33.6 43.1 37.7 86.5 23.9 31.7 30.6 129.0 13.4 50.2 30.9 114.3 12.7 51.3 8.9 30.2 28.6 15.5 16.4 19.3 26.7 18.5 37.3 16.6 28.4 52.6 16.1 34.2 43.7 54.0 127.1 75.1 131.4 96.6 33.0 116.2 137.3 76.5 88.7 30.3 47.5 47.1 57.3 113.1 53.1 104.1 112.4 109.2 115.5 105.4 40.7 20.6 69.5 44.4 83.2 69.8 49.6 88.7 236.1 116.2 100.5 69.9 11.7 38.6 10.7 92.1 108.9 67.0 69.0 15.6 30.6 24.0 30.4 70.6 72.8 61.4 84.4 145.2 132.8 116.8 143.5 41.5 200.6 52.1 56.7 32.4 18.9 184.9 30.5 35.5 59.2 85.9 90.0 35.7 64.0 48.3 99.8 29.2 13.3 31.2 16.3 19.7 19.7 16.7 13.8 14.7 16.4 17.3 12.0 17.7 10.2 18.1 19.4 33.6 17.0 14.2 23.3 28.5 28.6 26.1 20.0 28.8 28.8 33.6 30.6 28.6 26.7 34.2 13.3 38.5 18.7 8.8 22.5 45.9 58.2 79.6 59.2 41.5 307.0 132.2 19.6 10.0 66.4 42.3 33.3 6.6 36.7 4.0 1.9 53.1 21.3 37.1 76.1 12.9 25.6 4.6 13.0 37.8 56.7 45.6 9.2 73.8 23.5 18.9 8.9 11.0 20.4 23.5 23.9 7.4 38.7 20.1 30.0 18.1 37.3 26.0 67.6 1.9 25.7 38.2 10.3 34.2 36.5 39.5 1.9 47.8 24.4 197.9 2.7 13.6 44.3 41.3 39.5 40.4 38.6 43.9 27.8 32.6 74.4 23.8 23.2 23.0 5.7 69.3 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC40A1 "FPN1, HFE4, IREG1, MTP1, SLC11A3" ENSG00000138449 "Solute carrier family 40 member 1" Q9NP59 2 189560590-189583758 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 489.8;Kupffer cells: 1340.2;Syncytiotrophoblasts: 2463.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 326.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 509.0;CACO-2: 123.1;HEL: 430.0;HMC-1: 110.5;T-47d: 207.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065634 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 14: B-cells - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA065634: AB_2685524" "unprognostic (1.28e-2)" "unprognostic (1.73e-2)" "unprognostic (9.41e-2)" "unprognostic (1.83e-2)" "unprognostic (8.00e-3)" "unprognostic (1.36e-2)" "unprognostic (1.66e-1)" "unprognostic (6.22e-2)" "unprognostic (6.65e-2)" "unprognostic (1.84e-1)" "unprognostic (6.43e-2)" "unprognostic (6.44e-2)" "prognostic favorable (8.55e-5)" "unprognostic (4.66e-1)" "unprognostic (1.61e-1)" "unprognostic (8.96e-2)" "unprognostic (4.11e-2)" 59.6 333.5 9.3 52.6 11.9 45.8 97.7 9.6 9.8 156.3 10.4 124.7 289.3 95.4 61.6 30.5 214.2 148.7 52.6 7.2 12.0 79.9 251.5 122.9 172.6 15.6 15.7 317.2 53.2 91.8 19.0 250.1 12.8 39.5 130.8 29.5 58.7 53.1 64.2 12.2 127.9 69.3 15.5 368.1 96.8 33.2 13.9 62.6 68.0 60.3 59.1 53.1 21.8 11.3 0.0 7.4 0.6 0.0 509.0 3.3 25.4 0.2 6.6 1.9 3.1 123.1 0.4 0.2 1.0 0.2 1.4 0.4 2.4 0.3 1.6 0.3 1.7 430.0 1.7 45.8 1.9 1.5 110.5 35.9 0.2 1.2 0.0 11.7 13.0 16.4 44.6 1.1 6.3 0.0 18.2 28.8 1.5 92.7 1.7 0.2 5.0 2.5 5.3 18.1 1.0 5.4 0.8 35.4 0.0 39.5 207.6 6.2 0.3 0.8 11.7 0.5 0.1 1.1 0.2 0.3 0.1 0.2 0.1 129.8 101.5 172.1 2.2 23.7 3.2 0.2 54.4 4.9 115.6 0.7 80.2 17.8 326.2 4.6 2.6 18.8 5.3 105.8 9.3 11.9 9.6 9.8 7.2 12.0 15.6 15.7 12.8 15.5 13.9 11.3 44.2 125.0 40.3 3.6 12.0 9.2 51.3 10.5 19.9 4.8 83.8 30.0 48.0 138.7 31.6 33.1 4.2 489.8 5.7 328.9 49.0 54.7 10.5 39.6 38.2 39.8 18.6 253.7 0.3 71.8 20.3 81.9 76.5 129.5 9.5 12.8 245.9 259.7 86.4 6.7 6.8 60.8 6.1 1340.2 26.8 9.2 121.2 172.7 8.8 34.7 41.7 17.5 2.1 14.6 0.2 71.5 86.2 58.6 4.1 26.2 163.0 150.0 34.4 48.4 65.7 13.7 49.1 7.4 3.9 12.5 8.1 2463.5 11.9 84.8 48.9 27.7 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC43A1 "PB39, POV1, R00504" ENSG00000149150 "Solute carrier family 43 member 1" O75387 11 57484534-57515780 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "liver: 128.6;pancreas: 233.2" "Cell type enhanced" "Detected in many" "Cholangiocytes: 47.1;Erythroid cells: 82.9;Exocrine glandular cells: 35.4;Hepatocytes: 138.2" "Cancer enhanced" "Detected in all" "liver cancer: 45.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 62.7;NB-4: 74.3;U-937: 70.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018813, HPA018826" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 29: Non-specific - Vesicular transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus, Vesicles, Plasma membrane" "HPA018813: AB_1857164, HPA018826: AB_1857165" "unprognostic (3.04e-1)" "unprognostic (1.15e-1)" "unprognostic (9.19e-2)" "prognostic favorable (3.19e-4)" "unprognostic (2.51e-2)" "unprognostic (5.48e-2)" "unprognostic (2.32e-1)" "unprognostic (6.71e-3)" "unprognostic (1.63e-1)" "unprognostic (3.12e-2)" "unprognostic (6.06e-2)" "unprognostic (2.72e-1)" "prognostic unfavorable (2.97e-5)" "unprognostic (1.39e-2)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.27e-4)" "unprognostic (7.30e-2)" 13.9 10.7 3.6 4.7 4.2 35.7 11.1 2.7 5.0 13.1 2.7 15.7 8.7 12.6 10.3 4.4 13.5 18.2 8.6 3.6 2.8 7.3 128.6 9.9 7.4 3.8 3.2 20.3 233.2 1.8 4.4 6.3 3.5 12.8 9.4 1.3 13.8 6.2 17.1 18.8 9.2 8.7 2.7 8.5 30.4 3.4 3.4 2.1 12.7 9.1 6.6 16.2 9.9 3.9 1.1 1.7 1.8 20.3 25.7 18.8 0.2 10.4 13.8 3.0 7.6 6.5 2.8 59.5 2.7 7.9 3.9 1.0 18.1 1.2 3.7 2.8 4.6 30.9 0.5 62.7 33.7 54.3 7.2 23.8 4.4 5.2 23.2 7.3 13.4 34.7 43.9 10.7 3.8 2.3 0.5 74.3 6.6 27.0 13.6 51.0 9.8 27.2 0.5 0.1 23.5 3.6 1.9 0.3 23.8 0.5 1.6 27.3 5.5 3.1 7.1 26.2 1.7 12.1 4.3 35.3 1.5 70.6 4.2 11.1 6.2 0.7 10.9 2.4 9.2 2.9 4.9 7.7 8.4 1.5 4.9 6.9 0.5 7.5 0.2 1.9 9.5 5.5 3.6 4.2 2.7 5.0 3.6 2.8 3.8 3.2 3.5 2.7 3.4 3.9 4.4 0.0 7.3 1.6 3.3 7.0 1.6 0.0 3.4 5.7 1.8 2.4 6.8 47.1 0.6 0.0 0.0 0.2 3.6 3.1 3.9 3.4 21.5 5.3 6.0 4.7 6.0 82.9 3.5 35.4 0.4 10.9 4.6 13.4 3.8 1.3 15.4 138.2 7.4 0.0 1.4 8.8 0.0 8.1 2.9 14.8 15.5 3.2 5.4 5.6 1.3 0.2 5.2 4.0 0.6 11.1 2.9 7.9 6.2 3.2 0.3 0.1 0.7 0.4 6.6 6.4 7.7 0.7 1.5 0.3 3.7 0.1 6.4 2.9 9.0 0.9 SLC43A3 "DKFZp762A227, Eeg1, FOAP-13, PRO1659, SEEEG-1" ENSG00000134802 "Solute carrier family 43 member 3" Q8NBI5 11 57406954-57427580 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 146.9" "Cell type enhanced" "Detected in many" "Ductal cells: 75.5;granulocytes: 67.0;Hofbauer cells: 73.7;Langerhans cells: 74.6;Sertoli cells: 65.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "classical monocyte: 105.7;intermediate monocyte: 127.0;myeloid DC: 85.8;non-classical monocyte: 146.3;plasmacytoid DC: 85.7" "Group enriched" "Detected in all" 4 "dendritic cells: 85.8;monocytes: 146.3" "Cell line enhanced" "Detected in many" "HL-60: 513.8;HMC-1: 428.4;RPMI-8226: 570.9;WM-115: 532.1" "Region enhanced" "Detected in many" "olfactory bulb: 10.3" "Low region specificity" "Detected in all" "HPA030551, HPA077244" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA Yes "Cluster 51: Monocytes - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 25: RPMI-8226 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Nucleoplasm, Plasma membrane" "HPA030551: AB_10604094, HPA077244: AB_2732335" "unprognostic (2.64e-1)" "unprognostic (7.63e-2)" "unprognostic (9.67e-3)" "unprognostic (7.41e-3)" "unprognostic (6.59e-3)" "unprognostic (5.30e-3)" "unprognostic (1.29e-1)" "unprognostic (4.91e-2)" "unprognostic (1.36e-1)" "unprognostic (2.26e-1)" "unprognostic (5.73e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (3.97e-13)" "unprognostic (8.16e-2)" "unprognostic (1.77e-1)" "unprognostic (8.34e-2)" "unprognostic (1.00e-1)" 61.4 16.8 5.2 34.8 5.9 58.0 50.3 5.9 7.3 40.2 6.8 23.7 8.3 28.1 4.5 34.8 30.0 28.5 34.8 5.5 7.1 15.9 146.9 46.9 26.5 6.7 6.4 24.3 13.7 3.9 4.9 14.3 7.3 14.4 11.8 0.9 35.2 7.5 15.6 34.6 20.6 25.5 6.3 20.8 20.1 4.7 11.1 23.2 76.3 13.3 28.9 30.7 28.2 8.5 289.2 0.0 16.0 0.4 52.9 76.9 0.7 22.0 93.0 31.6 54.1 0.0 61.4 165.0 9.8 52.0 16.3 161.8 47.0 28.8 63.3 1.0 0.2 257.3 93.0 0.0 106.6 513.8 428.4 231.7 0.9 306.5 3.5 22.9 89.7 75.0 299.8 154.4 123.7 0.6 108.6 328.2 24.3 0.0 5.3 221.8 3.3 570.9 76.1 0.0 38.0 0.0 62.2 1.4 263.5 1.5 24.1 77.3 48.1 1.5 81.4 209.2 62.5 0.3 0.9 41.3 187.3 183.2 532.1 15.2 105.7 23.4 19.6 127.0 22.2 9.6 13.5 26.8 85.8 7.1 10.4 10.5 9.0 3.9 146.3 85.7 26.5 60.7 5.2 5.9 5.9 7.3 5.5 7.1 6.7 6.4 7.3 6.3 11.1 8.5 19.8 16.0 49.1 1.6 6.1 46.8 7.4 30.8 48.3 0.5 8.0 14.2 3.7 28.6 26.1 1.8 0.0 0.6 11.9 0.3 0.0 75.5 1.0 1.0 3.1 33.0 0.0 38.3 0.1 6.4 5.0 33.4 2.0 3.0 67.0 2.9 14.3 61.7 73.7 0.0 0.2 0.6 16.2 21.0 74.6 1.7 9.9 47.0 30.2 8.4 10.2 0.6 3.1 8.5 0.8 9.4 0.5 12.4 22.5 14.5 0.0 0.1 4.9 0.1 65.7 15.5 22.0 0.7 1.1 13.6 17.6 0.8 11.8 12.3 1.2 3.0 SLC44A2 CTL2 ENSG00000129353 "Solute carrier family 44 member 2" Q8IWA5 19 10602457-10644557 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 171.1;Extravillous trophoblasts: 257.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 333.2;SK-BR-3: 306.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003228, HPA070799" Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Vesicles, Cell Junctions" "HPA003228: AB_1080009, HPA070799: AB_2686314" "unprognostic (6.35e-3)" "unprognostic (5.75e-2)" "unprognostic (4.34e-1)" "unprognostic (3.06e-3)" "unprognostic (4.38e-2)" "unprognostic (8.41e-3)" "unprognostic (1.64e-1)" "unprognostic (2.52e-1)" "unprognostic (2.66e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (6.01e-4)" "unprognostic (8.63e-2)" "prognostic favorable (1.71e-5)" "unprognostic (1.28e-1)" "unprognostic (1.67e-1)" "unprognostic (8.21e-3)" "unprognostic (3.61e-2)" 74.7 33.2 69.6 43.9 85.0 65.0 72.7 78.4 67.4 64.6 33.4 58.3 26.7 43.0 36.2 81.6 59.0 55.8 71.4 62.7 69.7 68.7 17.8 98.5 75.3 99.6 76.5 32.3 41.2 48.7 20.5 157.5 87.0 43.8 49.5 29.1 55.5 65.8 141.2 78.3 50.8 43.6 84.3 115.5 112.9 82.5 79.1 48.8 64.9 92.4 77.7 56.3 69.2 97.6 333.2 8.3 70.0 42.1 103.9 63.5 201.1 69.6 169.5 112.3 131.6 75.6 154.9 65.6 91.1 193.9 13.6 254.1 10.7 53.2 71.6 1.7 9.3 42.0 39.3 3.1 115.0 0.6 33.9 69.2 69.8 42.3 37.2 91.0 86.8 30.2 20.2 10.8 172.6 243.6 35.1 32.1 24.9 96.9 29.3 74.1 102.7 2.9 37.1 171.8 6.9 42.0 56.7 306.1 7.7 73.8 123.0 3.2 79.8 50.1 18.4 60.5 18.0 4.0 7.9 64.8 12.5 29.1 57.3 146.3 39.4 227.9 114.1 113.0 90.4 92.1 78.5 87.4 20.7 94.8 83.3 87.1 482.8 79.2 278.3 100.4 95.7 147.4 69.6 85.0 78.4 67.4 62.7 69.7 99.6 76.5 87.0 84.3 79.1 97.6 84.0 54.5 29.1 32.3 53.4 9.7 17.3 17.2 13.1 12.3 45.8 29.1 38.6 28.6 47.7 92.0 14.6 137.8 51.9 49.9 1.9 44.1 171.1 15.8 31.4 52.7 9.6 45.0 14.3 44.3 257.0 22.6 84.6 38.6 20.3 7.1 75.7 1.9 37.0 3.3 15.5 17.7 14.2 38.7 3.9 35.1 38.8 22.8 5.4 15.9 10.2 36.4 88.6 18.6 18.4 41.1 31.9 56.4 18.9 9.8 20.1 3.7 19.0 3.0 59.2 26.3 29.4 3.2 2.9 33.5 8.5 93.4 41.2 6.8 23.4 20.6 SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 49.7;Cone photoreceptor cells: 54.2;Endometrial ciliated cells: 57.6;Glandular and luminal cells: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "HMC-1: 18.3;OE19: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" 3.5 2.5 3.8 3.7 4.8 5.8 2.9 1.2 16.6 7.1 14.7 4.4 2.3 4.3 1.5 3.3 7.1 2.7 6.6 5.1 1.5 10.2 0.9 6.7 2.7 6.6 1.0 3.1 7.9 2.5 14.9 5.0 6.6 6.6 1.6 5.4 7.8 5.3 4.6 5.7 4.1 1.7 0.7 4.8 12.5 13.7 2.2 2.3 5.8 1.4 2.0 3.4 2.8 6.1 4.6 9.8 3.7 5.9 0.3 0.3 16.1 2.5 1.5 2.2 1.7 6.4 12.2 0.9 11.8 1.0 3.1 3.7 2.1 1.2 1.0 7.2 3.3 2.7 3.1 0.0 1.7 1.1 18.3 0.8 1.9 1.6 0.9 0.5 1.5 5.0 5.6 0.7 0.8 11.9 11.0 2.5 4.7 30.8 4.1 3.3 0.2 3.1 8.9 7.9 5.5 4.6 2.7 0.8 4.5 2.6 1.9 7.2 0.8 0.0 2.4 3.8 4.9 3.9 12.7 1.3 2.1 4.3 4.0 1.1 0.1 8.3 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 7.0 0.2 0.1 0.3 0.2 0.1 3.8 4.8 1.2 16.6 5.1 1.5 6.6 1.0 6.6 0.7 2.2 6.1 3.3 9.6 12.7 6.5 3.0 2.7 6.6 3.6 5.2 33.1 6.4 5.8 13.5 15.7 8.9 49.7 54.2 8.7 7.5 14.7 0.0 9.3 12.5 57.6 10.8 3.4 2.4 0.0 29.0 2.7 0.8 2.9 37.2 97.1 1.3 1.8 1.1 0.0 6.7 3.3 21.7 7.7 8.2 2.5 3.3 5.9 2.1 8.6 3.6 7.5 1.8 4.3 5.2 6.6 0.9 7.8 4.5 2.2 5.3 6.0 3.7 3.2 22.3 9.2 0.0 1.5 3.2 5.7 2.6 4.4 2.4 16.3 4.6 4.0 5.1 11.3 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC46A3 "DKFZp686A1775, FLJ42613" ENSG00000139508 "Solute carrier family 46 member 3" Q7Z3Q1 13 28700064-28718970 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 76.0;liver: 96.0" "Cell type enhanced" "Detected in many" "Granulosa cells: 53.2;Hepatocytes: 51.3;Proximal enterocytes: 125.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 27.0;T-47d: 20.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039930 Approved Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "Actin filaments" "HPA039930: AB_10673263" "unprognostic (5.16e-2)" "unprognostic (1.01e-1)" "unprognostic (1.15e-1)" "unprognostic (2.61e-1)" "unprognostic (3.88e-1)" "unprognostic (1.22e-1)" "unprognostic (4.53e-3)" "prognostic favorable (7.09e-4)" "unprognostic (3.13e-1)" "unprognostic (3.33e-1)" "unprognostic (1.26e-1)" "unprognostic (5.69e-2)" "unprognostic (7.35e-2)" "unprognostic (1.14e-1)" "unprognostic (5.60e-2)" "unprognostic (9.14e-3)" "unprognostic (6.47e-3)" 13.8 11.7 5.1 10.2 5.7 2.9 10.0 7.7 5.2 14.7 10.0 19.8 46.7 5.6 11.1 4.0 7.5 23.8 12.3 4.7 5.7 18.2 96.0 11.5 16.3 5.9 6.0 3.9 6.7 23.9 10.2 9.5 6.1 6.5 18.8 15.9 9.0 9.9 8.5 4.2 76.0 8.2 6.6 18.2 7.8 11.0 6.6 11.6 12.5 8.6 11.1 7.0 2.2 5.6 0.0 2.8 0.0 7.6 6.0 2.3 0.2 2.7 15.7 3.0 4.4 0.1 6.6 5.2 4.7 4.0 11.5 0.6 3.5 1.4 4.5 3.9 6.2 3.6 0.0 0.0 11.4 0.0 4.3 9.8 2.9 4.5 7.3 3.0 5.6 15.7 3.9 0.0 14.5 3.0 8.6 0.6 0.3 8.0 2.2 3.5 13.3 0.2 27.0 0.9 1.2 0.4 0.0 14.1 5.7 3.1 20.6 4.6 2.0 1.4 2.7 0.4 16.0 4.0 2.0 0.8 0.9 0.0 2.8 33.1 8.9 3.8 10.3 13.1 8.6 7.4 8.0 10.1 11.7 9.7 11.4 10.8 9.8 7.0 19.4 11.0 10.6 8.7 5.1 5.7 7.7 5.2 4.7 5.7 5.9 6.0 6.1 6.6 6.6 5.6 6.2 0.0 5.4 16.0 14.5 1.9 0.1 7.4 1.8 33.7 15.1 3.3 9.6 17.2 15.6 9.2 8.4 0.6 16.4 49.0 1.9 15.5 4.6 2.1 1.7 12.2 3.6 4.6 11.6 5.6 0.3 6.2 0.0 2.1 25.9 53.2 17.5 51.3 10.8 21.9 13.0 6.8 2.0 32.1 36.6 1.8 1.5 22.5 7.2 16.9 9.3 14.2 12.3 14.6 15.6 3.5 5.3 2.2 6.5 0.6 125.0 10.1 15.4 9.8 0.0 2.8 7.2 2.6 0.9 4.9 1.7 0.7 11.4 16.8 13.9 0.2 SLC4A1AP "HLC3, kanadaptin" ENSG00000163798 "Solute carrier family 4 member 1 adaptor protein" Q9BWU0 2 27663471-27694976 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 143.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036679 Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Vesicles, Plasma membrane" "HPA036679: AB_2675244" "unprognostic (5.63e-2)" "unprognostic (1.01e-1)" "unprognostic (4.62e-2)" "prognostic unfavorable (1.49e-4)" "unprognostic (2.21e-1)" "unprognostic (7.89e-3)" "prognostic unfavorable (3.76e-7)" "unprognostic (1.32e-1)" "unprognostic (7.74e-2)" "unprognostic (1.83e-2)" "unprognostic (1.06e-1)" "unprognostic (9.66e-2)" "unprognostic (9.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.42e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.79e-4)" 13.7 16.6 15.3 16.1 16.2 15.8 14.5 17.9 20.9 11.8 12.7 12.3 12.6 13.4 12.4 15.1 12.7 10.4 20.6 16.4 16.2 16.0 16.2 13.9 17.4 15.7 15.6 15.5 14.4 21.1 12.7 15.7 15.7 12.9 12.9 19.8 12.9 12.0 30.6 16.4 13.3 13.2 13.3 15.0 13.9 33.9 15.6 17.1 15.3 22.1 16.9 12.6 12.0 16.4 44.6 25.4 25.1 23.6 25.3 23.2 36.8 36.1 24.8 37.2 30.3 37.4 31.7 28.0 32.7 29.1 39.2 31.0 40.6 28.0 33.2 39.2 33.2 32.2 26.2 41.5 30.7 46.6 29.5 20.9 34.8 37.1 34.8 31.2 38.4 27.1 47.5 29.7 34.7 27.1 31.5 45.4 25.4 29.3 24.7 25.9 54.9 32.4 38.5 20.4 27.2 26.8 28.1 37.9 36.0 25.2 23.0 30.1 39.3 34.5 31.3 24.2 42.7 48.5 73.8 88.4 37.4 36.8 28.2 104.8 33.4 48.9 31.6 32.6 31.8 26.1 28.6 28.0 25.8 36.7 34.5 29.1 31.9 43.7 37.6 20.8 34.9 28.0 15.3 16.2 17.9 20.9 16.4 16.2 15.7 15.6 15.7 13.3 15.6 16.4 17.1 32.1 28.9 14.7 17.3 11.9 12.3 27.1 14.8 19.9 13.3 11.0 30.1 11.5 29.1 18.4 18.8 24.5 21.0 11.4 5.9 28.4 47.2 22.0 20.3 21.9 16.3 11.8 25.5 36.9 20.3 17.4 13.3 20.4 38.6 18.5 15.4 13.9 24.4 25.2 23.7 11.5 16.2 13.9 8.2 7.9 17.4 18.9 17.8 8.4 31.5 21.6 19.6 12.5 18.2 30.5 9.3 19.2 22.1 8.7 11.5 16.1 24.4 21.1 32.9 23.3 21.7 143.4 82.4 15.7 11.9 24.4 21.8 21.5 10.1 10.8 SLC4A2 "AE2, BND3L, EPB3L1, HKB3, NBND3" ENSG00000164889 "Solute carrier family 4 member 2" P04920 7 151057210-151076526 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "choroid plexus: 492.1" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 91.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019339 Enhanced Uncertain "Nuclear speckles,Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Nuclear speckles, Plasma membrane" Cytosol "HPA019339: AB_1844825" "unprognostic (1.19e-1)" "unprognostic (3.33e-3)" "unprognostic (8.12e-3)" "unprognostic (1.10e-1)" "unprognostic (1.20e-1)" "unprognostic (1.49e-1)" "prognostic unfavorable (9.04e-6)" "unprognostic (1.24e-1)" "unprognostic (4.23e-1)" "unprognostic (3.30e-1)" "unprognostic (1.07e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.26e-4)" "unprognostic (4.67e-3)" "unprognostic (1.22e-1)" "unprognostic (1.28e-1)" "unprognostic (2.36e-2)" 28.4 34.8 16.9 19.2 29.4 12.7 23.7 29.1 21.9 38.9 492.1 45.0 22.5 40.3 4.9 21.0 31.1 19.7 31.3 39.4 23.2 38.6 52.3 33.2 13.1 32.8 27.9 31.9 52.5 72.4 13.8 27.0 32.0 28.2 7.1 4.7 23.1 14.0 18.8 21.7 29.3 16.5 20.2 27.0 82.2 13.7 32.7 12.4 25.4 12.3 6.3 31.9 25.8 40.2 60.9 196.9 37.8 78.9 37.6 17.9 87.1 72.9 37.0 56.9 48.0 113.0 91.6 35.8 154.1 35.0 84.6 58.2 38.2 31.4 9.8 105.3 59.1 48.5 91.9 57.5 59.6 25.2 147.0 29.0 27.4 65.6 15.7 60.9 31.3 50.6 151.8 27.1 44.3 118.0 69.2 43.3 90.4 80.7 73.2 55.2 21.2 42.2 44.6 41.0 31.5 113.9 67.0 118.4 62.0 27.3 51.2 46.7 72.0 78.1 39.1 77.5 106.5 31.2 47.7 20.5 118.7 61.4 160.6 0.0 1.6 0.4 0.8 1.6 0.7 0.9 0.7 0.7 1.0 0.3 0.7 0.8 0.2 0.1 1.0 2.1 0.2 0.9 16.9 29.4 29.1 21.9 39.4 23.2 32.8 27.9 32.0 20.2 32.7 40.2 15.6 9.6 8.2 9.8 7.2 11.1 5.9 13.6 15.4 7.7 14.5 11.9 4.0 18.6 9.6 20.2 25.0 36.1 14.2 17.6 17.6 35.7 1.0 21.9 18.9 13.6 27.6 2.5 0.4 35.8 9.4 13.6 30.1 17.0 47.1 62.1 17.9 34.6 26.0 15.2 1.4 12.1 16.2 16.1 12.0 1.6 13.7 17.0 26.6 4.7 11.6 21.6 3.1 3.0 16.8 43.8 14.0 19.9 9.9 5.9 24.9 19.1 11.4 8.2 13.1 12.8 17.6 3.1 7.9 10.6 7.0 91.5 8.5 11.2 22.1 4.5 SLC4A7 "NBC3, SBC2, SLC4A6" ENSG00000033867 "Solute carrier family 4 member 7" Q9Y6M7 3 27372721-27484420 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 57.6;retina: 72.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 733.9;Rod photoreceptor cells: 704.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "hTERT-HME1: 78.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022494, HPA035857" Enhanced Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Focal adhesion sites, Cytosol" "CAB022494: , HPA035857: AB_10795135" "unprognostic (2.94e-2)" "unprognostic (6.34e-2)" "unprognostic (1.80e-3)" "unprognostic (1.91e-1)" "unprognostic (8.48e-3)" "unprognostic (2.68e-1)" "unprognostic (6.79e-4)" "unprognostic (4.13e-2)" "unprognostic (1.40e-1)" "unprognostic (1.64e-1)" "unprognostic (1.83e-1)" "unprognostic (8.58e-3)" "prognostic unfavorable (7.91e-6)" "unprognostic (1.09e-2)" "unprognostic (6.68e-2)" "unprognostic (1.93e-1)" "unprognostic (7.26e-2)" 8.6 5.1 3.2 9.0 5.2 4.0 18.7 3.4 16.9 10.5 1.6 16.2 57.6 6.4 8.2 8.6 6.0 13.7 7.8 19.3 2.5 12.7 3.9 8.3 11.2 0.5 3.2 6.8 3.4 1.7 3.4 5.8 0.6 7.9 7.4 72.9 5.8 8.7 5.0 4.6 17.4 6.6 1.8 7.0 6.0 7.1 4.4 5.8 4.9 27.2 10.3 12.1 8.8 2.6 13.0 23.8 21.0 9.8 9.6 17.2 15.0 43.3 20.0 16.3 12.6 6.5 6.6 29.4 3.6 16.8 15.7 5.5 20.2 21.1 25.7 25.1 6.6 13.5 15.4 7.1 16.5 30.9 11.3 13.7 9.0 24.8 78.9 34.2 27.1 19.0 9.1 10.1 33.8 4.7 31.1 7.2 13.8 1.6 23.4 21.0 16.7 5.9 38.1 9.2 5.3 13.1 19.7 14.4 6.9 17.9 32.9 11.8 19.0 38.2 10.6 26.7 33.7 3.8 4.3 16.6 33.3 21.4 17.8 0.0 0.2 0.0 1.0 0.2 0.7 0.4 1.3 1.4 0.5 0.5 0.5 0.9 0.0 1.0 0.3 0.7 1.2 0.3 3.2 5.2 3.4 16.9 19.3 2.5 0.5 3.2 0.6 1.8 4.4 2.6 30.0 0.0 11.2 10.7 37.5 29.3 39.5 23.4 11.4 130.2 72.4 30.4 23.1 21.5 22.8 62.5 733.9 5.8 51.8 5.5 9.8 15.5 10.2 73.6 40.7 53.6 38.2 7.2 46.2 7.1 29.3 52.2 15.8 124.1 23.5 24.6 17.5 6.2 17.0 6.7 88.7 58.5 36.7 48.4 61.6 7.6 9.0 46.5 35.6 185.5 26.7 45.7 20.6 60.8 20.9 19.1 23.4 9.8 27.8 93.1 142.5 10.2 9.6 704.2 39.5 56.4 43.7 40.0 21.7 21.7 30.7 8.1 56.1 19.0 26.7 35.2 SLC4A8 NBC3 ENSG00000050438 "Solute carrier family 4 member 8" Q2Y0W8 12 51391317-51515763 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.1;pituitary gland: 17.9;retina: 11.1;testis: 11.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.6;Cone photoreceptor cells: 179.3;Excitatory neurons: 115.0;Horizontal cells: 116.1;Inhibitory neurons: 127.8;Oligodendrocytes: 248.9;Spermatocytes: 91.9" "Group enriched" "Detected in some" 6 "breast cancer: 1.7;glioma: 2.7;testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 21.0;HMC-1: 14.8;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077895 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA077895: " "unprognostic (4.01e-1)" "unprognostic (8.15e-2)" "unprognostic (2.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.96e-2)" "unprognostic (3.46e-2)" "unprognostic (7.72e-4)" "unprognostic (3.13e-2)" "unprognostic (7.03e-3)" "unprognostic (1.07e-4)" "unprognostic (1.70e-1)" "unprognostic (9.60e-6)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" 0.2 3.1 6.7 0.9 7.5 0.6 1.3 10.3 18.1 1.1 0.0 0.4 0.4 0.3 2.5 0.1 1.7 0.3 0.3 9.8 10.6 1.9 0.1 1.2 1.4 23.3 8.6 3.3 1.0 2.2 17.9 0.2 24.1 0.4 0.4 11.1 0.9 0.6 0.1 0.2 0.8 0.3 3.6 1.0 1.3 11.7 9.0 0.6 0.2 0.0 1.2 0.2 0.1 11.4 0.2 1.0 11.9 0.1 0.5 0.6 21.0 3.3 5.5 5.2 3.3 7.2 0.2 4.5 0.5 4.5 2.9 0.1 4.7 0.2 4.8 0.9 0.6 2.3 0.3 0.0 0.0 0.7 14.8 0.2 0.2 2.7 0.5 3.1 6.2 1.9 0.1 7.6 2.7 2.6 6.6 1.4 5.1 1.4 3.6 0.1 0.0 0.0 0.6 0.1 15.7 10.7 1.3 1.6 0.0 3.6 2.0 0.5 5.7 3.3 1.7 0.2 4.3 3.8 1.3 0.2 4.6 0.6 0.4 0.4 0.5 0.9 0.4 0.3 0.0 0.1 0.1 0.4 0.7 0.2 0.1 0.2 0.5 0.5 0.8 0.2 0.0 0.2 6.7 7.5 10.3 18.1 9.8 10.6 23.3 8.6 24.1 3.6 9.0 11.4 1.2 0.0 8.7 33.6 3.1 0.0 0.8 0.2 0.0 92.6 5.0 1.5 1.9 0.0 5.4 1.8 179.3 1.4 4.9 0.5 7.9 0.1 61.9 1.7 0.6 2.4 6.0 0.8 115.0 1.3 5.2 2.1 13.3 0.7 7.6 11.5 1.1 0.2 2.2 116.1 127.8 0.4 0.0 4.7 2.2 32.8 2.8 4.5 1.8 18.7 3.4 11.5 7.2 20.1 248.9 0.1 5.4 3.8 3.5 1.0 1.9 1.0 25.0 19.9 0.0 0.7 1.0 91.9 8.2 0.1 0.1 0.4 4.3 0.9 0.2 1.1 SLC4A9 AE4 ENSG00000113073 "Solute carrier family 4 member 9" Q96Q91 5 140360194-140375141 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Transport" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 24 "kidney: 35.5" "Cell type enhanced" "Detected in some" "Distal tubular cells: 1.9;Excitatory neurons: 2.4;Inhibitory neurons: 2.4;Ionocytes: 2.0;Oligodendrocyte precursor cells: 1.5;Oligodendrocytes: 6.4;Spermatocytes: 1.7;Spermatogonia: 1.9" "Cancer enriched" "Detected in single" 8 "renal cancer: 0.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA051307 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" Vesicles "HPA051307: AB_2681434" "unprognostic (1.68e-1)" "unprognostic (4.22e-2)" "unprognostic (2.20e-1)" "unprognostic (1.47e-1)" "unprognostic (1.10e-1)" "unprognostic (2.13e-1)" "unprognostic (1.02e-2)" "unprognostic (3.28e-3)" "unprognostic (2.78e-1)" "unprognostic (2.47e-1)" "unprognostic (4.78e-2)" "unprognostic (1.19e-1)" "unprognostic (4.24e-2)" "unprognostic (2.99e-2)" "unprognostic (3.06e-2)" "unprognostic (5.04e-2)" "unprognostic (1.82e-2)" 0.1 0.0 0.3 0.0 0.7 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.5 35.5 0.0 0.1 0.0 0.9 0.6 0.0 0.1 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.6 0.0 0.2 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.4 0.7 0.3 0.5 0.9 0.6 1.0 0.5 0.6 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.4 1.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.0 2.0 0.0 0.0 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.5 6.4 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.0 1.7 1.9 0.0 0.1 0.0 0.1 0.1 0.1 0.2 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 96.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 129.1;Collecting duct cells: 138.0;Granulosa cells: 148.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA029791: AB_10601892" "unprognostic (9.70e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (4.48e-3)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" 6.9 5.9 8.6 4.5 9.2 1.9 6.6 5.7 11.4 3.7 96.0 4.5 2.6 6.8 5.2 3.1 4.8 2.5 2.4 10.7 17.0 29.0 5.9 3.9 4.9 9.3 9.9 3.9 1.9 3.2 4.1 10.6 9.2 2.9 5.2 5.6 2.8 3.5 2.5 6.7 3.7 2.9 8.2 2.4 3.9 6.2 20.3 3.9 25.2 2.6 4.8 3.8 3.4 9.2 10.5 9.3 19.0 13.4 15.5 12.7 9.1 11.8 35.7 7.2 10.9 15.5 22.5 16.9 9.3 24.0 13.5 5.3 23.3 6.7 12.2 17.7 6.0 17.5 9.0 5.2 4.1 7.6 7.1 6.1 17.0 19.7 7.8 22.0 4.4 13.7 17.6 3.9 18.7 7.1 8.1 6.1 9.6 4.0 9.0 8.1 3.4 7.7 28.1 14.5 9.9 4.6 24.5 6.4 5.6 11.3 3.9 8.0 4.2 14.0 10.7 27.1 4.8 20.1 18.5 12.4 28.2 10.9 9.6 0.0 0.2 0.0 0.6 0.2 0.5 0.1 0.3 0.4 0.2 0.1 0.4 0.6 0.1 0.2 0.1 0.5 0.1 0.1 8.6 9.2 5.7 11.4 10.7 17.0 9.3 9.9 9.2 8.2 20.3 9.2 18.8 16.0 10.2 0.0 33.3 0.0 46.5 0.0 129.1 33.8 37.4 34.9 11.4 10.0 13.0 138.0 20.9 27.4 43.0 39.1 21.5 4.0 9.0 38.7 59.9 16.4 49.3 17.0 0.0 5.5 19.7 42.3 18.3 42.5 41.3 148.6 5.0 20.7 15.2 37.0 0.0 69.3 0.0 14.4 0.0 7.2 6.5 41.0 0.0 0.0 23.3 6.7 16.5 0.0 0.0 7.6 49.7 20.7 54.1 88.4 16.3 9.4 8.7 20.9 13.1 15.4 33.7 14.8 18.5 39.7 0.0 28.2 48.3 14.0 36.3 69.5 SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.1;Extravillous trophoblasts: 111.7;Hepatocytes: 67.7;Syncytiotrophoblasts: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 310.9;SK-BR-3: 337.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" 42.4 8.6 27.5 14.2 25.2 18.1 31.5 24.0 30.6 9.4 46.2 13.0 20.9 14.3 67.4 10.9 11.5 7.5 7.7 23.4 23.9 8.5 104.0 7.9 13.8 24.0 24.4 10.2 11.6 9.8 8.0 39.1 25.9 9.3 12.7 6.4 12.5 11.1 17.0 10.0 15.3 9.7 23.9 9.1 10.1 23.4 30.6 11.6 8.0 8.8 26.5 11.3 8.8 21.9 78.9 79.6 49.9 66.1 45.4 16.5 310.9 28.1 19.1 41.8 28.7 118.8 27.0 54.2 41.3 15.4 44.7 42.8 108.3 32.4 29.1 42.2 63.5 96.6 34.9 184.4 53.8 125.1 47.8 57.1 27.1 51.4 39.7 11.1 38.2 43.3 143.6 21.1 27.0 161.0 42.7 60.4 144.8 90.1 29.0 70.7 58.7 78.2 24.0 74.5 42.0 61.7 30.3 337.1 40.1 48.6 74.9 26.0 17.5 45.3 62.5 27.9 76.1 35.7 88.6 84.7 24.5 86.1 65.2 0.1 5.9 1.8 7.4 6.6 8.9 5.8 7.0 7.0 8.7 5.3 7.1 8.6 0.3 6.3 8.9 8.9 7.6 5.8 27.5 25.2 24.0 30.6 23.4 23.9 24.0 24.4 25.9 23.9 30.6 21.9 2.5 0.0 4.4 7.8 13.4 8.0 8.6 3.8 7.4 5.3 41.9 31.9 6.8 8.6 3.1 7.3 4.2 119.1 12.5 6.7 1.9 9.8 15.1 3.9 7.4 6.2 5.4 12.6 7.2 8.2 111.7 6.0 5.6 6.9 0.0 18.1 7.1 67.7 21.8 11.8 9.0 9.2 4.1 9.1 6.0 32.0 7.2 6.6 0.0 29.0 47.9 2.5 6.2 6.6 5.0 7.0 4.3 13.9 10.0 14.1 11.7 3.9 2.9 3.1 13.1 5.5 5.2 35.1 21.5 7.6 6.3 227.9 8.6 9.4 15.2 7.8 SLC5A7 "CHT1, hCHT" ENSG00000115665 "Solute carrier family 5 member 7" Q9GZV3 2 107986523-108013994 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Neurotransmitter biosynthesis, Sodium transport, Symport, Transport" "Congenital myasthenic syndrome, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 32.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Club cells: 3.1;Respiratory ciliated cells: 1.5" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 20 "RT4: 3.6;SCLC-21H: 1.0" "Group enriched" "Detected in many" 4 "basal ganglia: 23.1;hypothalamus: 9.0;midbrain: 9.4;pons and medulla: 14.4;thalamus: 6.2" "Group enriched" "Detected in many" 6 "basal ganglia: 20.4;pons: 26.5;spinal cord: 46.7" HPA046105 Approved "Nuclear bodies,Cell Junctions,Intermediate filaments" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 15: RT4 - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cell Junctions, Intermediate filaments" "Nuclear bodies" "HPA046105: " "unprognostic (2.98e-1)" "unprognostic (1.01e-1)" "unprognostic (1.29e-3)" "unprognostic (7.10e-2)" "unprognostic (1.66e-1)" "unprognostic (3.39e-4)" "unprognostic (1.05e-2)" "unprognostic (9.78e-3)" "unprognostic (6.42e-2)" "unprognostic (1.61e-2)" 0.1 0.7 1.1 0.5 3.0 0.0 0.1 0.0 10.3 0.7 1.0 2.6 0.7 0.1 0.1 0.3 0.1 0.1 0.3 0.2 5.3 0.3 0.0 0.2 0.0 20.2 21.2 0.2 0.1 0.0 0.0 0.0 32.9 0.3 0.7 0.9 0.3 1.1 0.0 0.0 0.8 0.7 2.8 0.0 0.5 0.1 1.6 0.0 1.2 0.1 0.0 1.3 0.6 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 3.0 0.0 10.3 0.2 5.3 20.2 21.2 32.9 2.8 1.6 7.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.3 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 SLC6A6 TAUT ENSG00000131389 "Solute carrier family 6 member 6" P31641 3 14402576-14489349 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 68.5" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 571.3;Rod photoreceptor cells: 547.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 59.2" "Lineage enriched" "Detected in all" 6 "granulocytes: 59.2" "Cell line enhanced" "Detected in many" "HeLa: 66.6;RPTEC TERT1: 111.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015028, HPA016488" Enhanced Approved "Cell Junctions,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 34: Non-specific - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 9: Photoreceptor cells - Phototransduction" "Cell Junctions, Cytosol" "HPA015028: AB_1857200, HPA016488: AB_1857202" "unprognostic (8.25e-2)" "unprognostic (7.29e-3)" "unprognostic (2.63e-2)" "prognostic favorable (5.22e-5)" "prognostic unfavorable (5.75e-8)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.58e-1)" "unprognostic (2.56e-1)" "unprognostic (3.81e-1)" "unprognostic (6.96e-2)" "unprognostic (2.38e-1)" "unprognostic (2.78e-3)" "unprognostic (1.11e-1)" "unprognostic (1.01e-2)" "unprognostic (9.65e-2)" "unprognostic (1.90e-1)" 10.9 25.6 1.7 8.4 6.9 54.7 8.5 5.0 7.7 11.3 0.0 3.9 0.9 10.4 0.0 6.7 6.7 9.4 24.4 3.5 3.8 12.2 1.5 20.5 7.5 9.6 6.6 28.9 2.3 2.5 7.4 7.9 6.7 4.3 2.4 68.5 17.1 7.2 30.9 18.3 17.1 6.9 1.7 15.6 9.4 3.7 11.0 4.5 9.3 8.7 9.1 8.1 6.1 6.8 4.1 18.4 4.6 10.1 11.6 5.7 15.9 4.3 26.4 8.4 6.2 8.8 5.6 12.6 4.5 10.9 11.7 4.3 4.5 10.1 16.5 3.7 9.7 8.8 66.6 24.2 0.0 3.7 22.3 1.9 2.6 7.8 1.6 7.7 14.5 6.2 10.1 3.5 18.6 8.1 9.4 20.3 6.1 7.1 10.8 6.1 7.3 24.9 111.8 28.5 7.2 4.6 3.1 3.2 0.6 36.8 11.5 4.5 15.3 9.7 3.9 5.2 6.2 3.9 6.0 7.1 19.3 6.6 23.2 5.6 9.2 8.6 2.5 7.3 1.3 4.0 2.7 3.0 2.8 2.1 0.5 0.6 59.2 1.8 9.4 1.4 8.7 4.6 1.7 6.9 5.0 7.7 3.5 3.8 9.6 6.6 6.7 1.7 11.0 6.8 42.7 6.4 21.5 1.3 16.4 49.3 17.1 51.5 43.9 126.1 9.5 6.9 4.2 7.2 52.8 20.2 571.3 3.0 14.5 0.5 0.0 12.0 19.6 82.1 23.0 29.4 14.4 9.4 17.4 8.2 15.8 13.5 29.0 126.9 13.3 2.5 11.7 0.6 27.2 10.1 18.5 3.5 46.8 60.1 59.5 16.6 17.4 58.8 17.8 32.8 110.9 30.8 10.3 3.0 23.9 31.1 12.6 17.3 13.3 17.6 51.3 23.3 69.5 547.8 0.0 11.4 8.3 0.4 1.3 15.7 23.9 5.1 25.5 46.8 3.6 16.8 SLC7A14 "KIAA1613, PPP1R142" ENSG00000013293 "Solute carrier family 7 member 14" Q8TBB6 3 170459548-170586075 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Retinitis pigmentosa" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 15.9;pituitary gland: 7.3;retina: 6.1" "Group enriched" "Detected in some" 5 "Bipolar cells: 28.4;Excitatory neurons: 61.9;Horizontal cells: 28.6;Inhibitory neurons: 90.2;Oligodendrocytes: 67.4" "Group enriched" "Detected in some" 11 "glioma: 0.8;pancreatic cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "LHCN-M2: 3.2;SCLC-21H: 3.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045929 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Cytosol" "Nucleoplasm, Plasma membrane" "HPA045929: AB_2679501" "unprognostic (1.00e-1)" "unprognostic (9.56e-2)" "unprognostic (1.03e-1)" "unprognostic (4.15e-2)" "unprognostic (1.43e-2)" "unprognostic (7.46e-2)" "unprognostic (9.16e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-1)" "unprognostic (6.68e-3)" "unprognostic (6.36e-2)" "unprognostic (3.03e-6)" "unprognostic (1.54e-2)" "unprognostic (8.05e-2)" "unprognostic (1.71e-2)" "unprognostic (3.24e-3)" 0.0 2.3 8.9 0.4 8.1 0.1 0.0 5.5 8.8 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 7.9 15.9 0.1 0.0 0.0 0.0 15.6 6.4 0.1 0.7 0.0 7.3 0.0 14.9 0.1 0.4 6.1 0.0 0.0 0.1 0.1 0.3 0.1 4.0 0.0 0.2 0.1 8.9 0.0 0.0 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.1 0.0 0.5 0.9 0.0 0.3 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.5 0.3 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 8.9 8.1 5.5 8.8 7.9 15.9 15.6 6.4 14.9 4.0 8.9 7.7 0.8 3.2 2.2 4.6 0.1 0.4 0.3 0.1 0.0 28.4 0.1 0.0 1.0 0.0 2.5 0.0 2.1 0.1 0.1 0.0 0.0 0.0 0.6 0.2 0.2 0.5 1.8 0.0 61.9 0.0 0.1 0.4 0.0 0.1 2.5 0.1 0.4 0.9 0.0 28.6 90.2 0.1 0.0 0.0 1.2 0.6 2.1 0.4 3.6 6.5 0.0 1.8 0.0 9.5 67.4 0.1 1.2 2.6 0.1 0.3 0.1 0.2 3.0 4.3 0.0 0.7 0.5 0.0 0.2 0.0 0.6 0.0 0.4 0.1 0.0 0.2 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 SLC7A5 "CD98, D16S469E, E16, LAT1, MPE16" ENSG00000103257 "Solute carrier family 7 member 5" Q01650 16 87830023-87869507 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 110.7;brain: 121.9" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 178.7;Microglial cells: 109.6;Plasma cells: 135.1;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 10 "plasmacytoid DC: 17.2" "Lineage enriched" "Detected in many" 10 "dendritic cells: 17.2" "Cell line enhanced" "Detected in all" "HBEC3-KT: 1326.5;hTCEpi: 2229.0;MCF7: 1264.6;SiHa: 1873.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052673, HPA056077" Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA 51000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" Vesicles "HPA052673: AB_2681909, HPA056077: AB_2683031" "unprognostic (2.71e-3)" "unprognostic (1.10e-2)" "unprognostic (1.02e-1)" "unprognostic (2.64e-1)" "unprognostic (3.22e-2)" "unprognostic (2.99e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (6.86e-2)" "unprognostic (4.46e-2)" "unprognostic (1.27e-1)" "unprognostic (3.17e-1)" "prognostic unfavorable (0.00e+0)" "unprognostic (5.93e-2)" "unprognostic (5.52e-3)" "unprognostic (1.64e-2)" "unprognostic (7.19e-3)" 10.6 3.9 121.9 18.3 87.8 110.7 6.0 89.5 119.4 11.0 64.5 11.4 6.6 5.2 35.7 100.2 6.4 6.6 21.1 96.0 91.0 18.0 26.6 9.8 14.1 111.3 104.3 8.1 14.0 1.8 22.8 17.0 104.9 9.8 2.7 42.5 28.6 10.4 30.1 25.1 8.9 3.2 93.0 16.7 34.4 65.6 117.1 6.9 3.9 2.8 11.5 24.6 22.6 88.1 187.4 693.5 13.2 192.1 5.1 10.6 487.3 147.1 52.8 87.4 56.3 456.3 260.4 170.1 126.7 187.6 30.5 818.3 142.5 1326.5 61.0 179.9 71.9 140.3 618.0 331.2 199.5 131.2 246.0 35.9 2229.0 107.8 791.4 28.5 18.0 588.8 212.6 185.1 71.1 1264.6 159.2 192.7 63.3 116.7 166.0 152.0 52.4 264.1 98.3 15.7 109.2 43.5 1873.1 368.9 406.9 123.0 170.0 171.8 14.3 30.9 201.3 127.8 114.5 237.9 213.2 728.2 120.1 322.1 296.4 1.0 0.0 0.0 1.0 0.0 1.3 0.5 0.5 0.9 0.4 0.0 0.1 0.4 0.2 0.2 0.0 17.2 1.6 0.5 121.9 87.8 89.5 119.4 96.0 91.0 111.3 104.3 104.9 93.0 117.1 88.1 3.7 0.0 0.6 8.1 23.0 73.3 17.9 27.0 178.7 15.2 12.0 8.9 2.9 2.8 6.3 1.8 16.7 15.4 80.0 3.4 0.0 18.1 1.0 20.5 7.6 29.1 86.3 86.3 12.0 9.6 35.4 9.5 43.3 51.0 66.9 4.5 1.8 17.3 9.2 10.1 13.2 6.3 8.2 3.0 50.5 5.0 1.8 51.0 39.2 109.6 2.6 14.8 2.1 15.1 1.6 25.7 2.3 1.5 135.1 18.2 1.0 0.4 3.2 52.7 0.0 33.6 31.5 1.6 4.5 58.8 37.5 107.4 65.8 2.7 4.2 42.8 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.5;stomach 1: 65.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.5;Gastric mucus-secreting cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 9.6 10.7 6.1 10.4 14.7 11.5 9.0 2.8 10.8 10.9 0.2 18.6 29.3 10.9 8.0 11.0 7.6 16.9 13.7 2.3 5.3 5.8 2.4 13.2 7.0 13.8 4.7 7.0 8.6 20.7 8.2 21.9 11.2 9.0 13.6 4.5 76.5 19.4 4.6 10.5 19.0 10.7 0.5 11.6 65.9 10.1 10.4 6.3 9.5 4.9 6.7 15.1 9.2 2.4 32.3 10.7 9.9 10.1 21.8 15.7 60.8 25.9 38.5 21.7 23.5 13.0 20.0 14.4 21.9 33.4 10.5 38.9 9.8 62.4 13.4 17.4 9.4 21.9 7.1 5.5 66.1 13.1 16.0 19.7 29.5 36.5 50.7 15.8 36.3 9.8 6.3 13.4 32.3 18.7 6.8 6.4 14.0 38.2 21.9 11.8 9.0 6.7 10.9 46.3 11.4 3.7 21.5 28.4 12.6 10.0 13.3 7.9 39.9 23.0 9.4 21.7 14.5 12.6 8.6 4.3 24.6 14.1 13.5 0.0 0.6 0.6 0.7 0.3 1.5 0.1 0.8 0.7 0.2 0.3 0.5 0.6 2.0 0.1 0.6 0.0 0.3 0.8 6.1 14.7 2.8 10.8 2.3 5.3 13.8 4.7 11.2 0.5 10.4 2.4 13.5 6.4 14.8 6.5 7.9 31.2 17.9 14.6 13.1 7.4 21.7 23.2 13.5 7.2 8.3 11.0 0.0 40.3 11.9 81.5 0.0 9.1 26.5 13.8 15.9 9.7 12.5 0.4 14.1 12.5 19.4 12.7 160.0 26.5 27.3 7.5 6.8 1.2 12.9 20.2 14.1 15.0 4.1 5.7 5.1 14.4 9.3 12.7 7.2 8.4 4.3 8.2 12.3 4.0 4.6 28.1 43.1 13.2 4.8 9.6 38.9 1.2 5.9 3.8 6.6 20.8 9.8 3.6 4.4 15.0 25.1 52.9 9.8 4.8 18.3 18.3 SLC9A2 NHE2 ENSG00000115616 "Solute carrier family 9 member A2" Q9UBY0 2 102619553-102711355 "Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.7;stomach 1: 26.4" "Cell type enhanced" "Detected in some" "Distal enterocytes: 41.3;Early spermatids: 46.5;Gastric mucus-secreting cells: 41.8;Intestinal goblet cells: 23.4;Late spermatids: 31.4;Paneth cells: 38.7;Undifferentiated cells: 29.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 10.0;OE19: 37.3;RT4: 16.9;SK-BR-3: 14.7;T-47d: 18.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA035121, HPA035122" Approved Supported "Cell Junctions" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Cell Junctions" "HPA035121: AB_10602894, HPA035122: AB_2674477" "unprognostic (1.53e-2)" "unprognostic (8.05e-3)" "unprognostic (6.00e-2)" "unprognostic (3.00e-3)" "unprognostic (3.12e-1)" "unprognostic (1.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.86e-1)" "unprognostic (1.55e-1)" "unprognostic (1.23e-1)" "unprognostic (2.37e-2)" "unprognostic (1.97e-1)" "unprognostic (1.40e-3)" "unprognostic (1.60e-1)" "unprognostic (7.51e-2)" "unprognostic (1.39e-2)" "unprognostic (1.70e-1)" 0.0 0.1 1.4 2.1 0.7 0.0 1.4 0.8 1.5 1.4 0.2 20.0 6.3 0.1 3.9 0.3 0.3 1.1 0.0 1.9 0.9 5.4 0.0 0.1 0.1 1.4 0.7 0.0 0.0 5.8 1.0 0.0 1.5 5.8 20.7 0.1 4.9 2.1 6.4 0.8 3.4 0.7 0.8 0.0 26.4 5.7 1.2 0.4 1.0 6.2 4.5 1.0 0.0 0.5 10.0 6.1 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 0.2 0.0 3.4 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.3 3.4 2.9 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 7.7 0.0 0.1 0.2 37.3 5.0 0.0 0.1 0.0 1.1 16.9 0.1 0.0 0.0 14.7 0.0 0.0 18.5 0.0 0.0 0.0 0.7 0.0 1.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.7 0.8 1.5 1.9 0.9 1.4 0.7 1.5 0.8 1.2 0.5 0.0 0.0 0.0 2.0 0.3 0.4 0.2 0.1 0.0 0.0 1.1 0.1 0.8 0.0 0.3 9.2 0.0 0.5 0.0 41.3 0.0 0.2 46.5 0.5 0.2 0.3 9.7 0.0 3.0 0.0 0.0 0.0 41.8 3.1 0.0 0.0 0.0 0.0 0.1 0.0 14.6 23.4 6.1 0.0 0.4 31.4 0.6 0.0 0.0 5.6 0.0 0.5 0.0 1.0 1.0 8.5 38.7 0.0 0.2 4.1 3.2 1.4 0.1 0.1 0.0 0.5 0.1 4.5 0.2 0.0 0.6 0.3 0.2 0.0 29.6 0.8 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SLC9A3R1 "EBP50, NHERF, NHERF1" ENSG00000109062 "SLC9A3 regulator 1" O14745 17 74748628-74769353 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Wnt signaling pathway" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 352.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 295.8;Proximal enterocytes: 536.9;Proximal tubular cells: 433.0;Squamous epithelial cells: 303.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 572.4;SK-BR-3: 450.7;T-47d: 873.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001962, HPA009672, HPA027247" Enhanced Approved "Vesicles,Plasma membrane,Centriolar satellite" NA Yes 940000 "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Vesicles, Centriolar satellite" "CAB001962: , HPA009672: AB_1857215, HPA027247: AB_10601162" "unprognostic (1.29e-1)" "unprognostic (4.58e-2)" "unprognostic (1.73e-2)" "unprognostic (5.51e-2)" "unprognostic (5.83e-2)" "unprognostic (1.73e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (7.41e-2)" "unprognostic (5.61e-2)" "unprognostic (5.38e-2)" "unprognostic (7.53e-2)" "unprognostic (4.49e-2)" "unprognostic (1.56e-3)" "unprognostic (7.81e-3)" "unprognostic (5.53e-2)" "unprognostic (3.84e-2)" "unprognostic (2.08e-2)" 27.0 146.3 98.9 43.7 103.0 115.7 64.1 105.6 118.1 58.3 127.5 85.1 257.8 22.6 26.0 352.8 89.7 96.6 24.3 98.3 91.0 203.5 269.2 26.5 67.9 100.2 97.6 11.1 85.4 110.3 20.8 33.6 95.6 43.9 59.3 13.0 192.2 71.1 5.2 51.1 274.4 11.6 92.2 61.1 78.2 22.5 102.0 57.7 21.4 10.0 89.2 25.7 103.3 106.1 102.1 82.6 40.4 42.1 23.9 17.5 179.9 24.1 22.4 60.3 58.2 259.6 59.6 22.2 23.9 51.4 32.3 142.2 69.8 46.4 28.3 25.9 66.2 167.4 210.9 350.8 48.6 110.3 108.9 14.4 25.6 48.0 20.6 124.9 50.2 65.8 54.0 115.9 93.8 572.4 262.5 246.7 36.1 286.3 47.6 28.0 45.4 100.6 83.5 71.7 34.6 45.3 25.2 450.7 51.9 110.4 873.8 87.3 17.0 18.7 53.5 43.8 40.2 200.0 98.9 40.9 30.2 145.4 11.2 581.6 91.9 440.8 421.5 133.0 279.8 58.6 255.5 360.4 87.8 52.1 147.5 266.1 318.8 308.8 172.1 90.8 309.0 345.9 98.9 103.0 105.6 118.1 98.3 91.0 100.2 97.6 95.6 92.2 102.0 106.1 12.3 6.4 17.2 29.0 41.8 46.1 21.4 128.7 50.1 2.2 135.3 78.7 17.8 163.0 120.8 31.3 4.2 74.5 122.9 295.8 66.5 194.9 15.8 61.8 7.8 12.0 18.7 24.8 0.4 99.0 56.6 24.7 45.3 85.0 25.3 7.3 7.9 190.6 85.4 5.0 0.5 58.0 105.8 25.7 18.8 9.9 8.7 43.5 28.4 3.7 27.0 86.2 203.9 5.0 11.4 76.5 143.8 41.8 151.1 27.5 536.9 433.0 76.0 5.0 6.6 27.6 20.0 22.5 19.5 303.4 57.4 111.5 126.1 17.1 57.1 34.6 SLC9A3R2 "E3KARP, NHERF-2, SIP-1, TKA-1" ENSG00000065054 "SLC9A3 regulator 2" Q15599 16 2025356-2039026 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 568.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1013.8;Endothelial cells: 398.9;Hepatic stellate cells: 374.4;Hepatocytes: 227.4;Pancreatic endocrine cells: 326.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.9;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.9;monocytes: 2.2" "Cell line enhanced" "Detected in many" "A549: 188.6;MCF7: 306.8;PC-3: 281.2;SK-BR-3: 188.3;U-251 MG: 193.6;WM-115: 202.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001672, HPA066520" Enhanced Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001672: AB_1080017, HPA066520: AB_2732748" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (2.06e-2)" "prognostic favorable (1.03e-4)" "unprognostic (1.41e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-3)" "unprognostic (9.17e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.70e-2)" "unprognostic (2.20e-2)" "unprognostic (6.20e-3)" "unprognostic (9.10e-2)" "unprognostic (2.40e-1)" "unprognostic (2.80e-2)" 234.7 81.7 107.0 20.7 98.6 0.7 181.7 83.4 119.7 92.6 60.6 77.4 27.2 92.7 10.7 47.3 77.7 34.8 568.2 82.4 88.5 207.5 408.3 289.1 22.0 96.4 95.5 57.9 47.7 24.0 95.6 51.3 99.3 129.1 11.9 3.0 149.1 42.4 144.6 45.3 81.2 18.8 87.0 143.8 109.5 36.3 116.2 7.9 188.4 109.0 7.4 77.4 72.6 94.7 32.5 188.6 5.0 38.6 6.2 8.6 5.7 138.1 81.9 67.9 22.5 25.4 41.9 0.1 63.4 59.2 9.1 30.9 15.0 13.7 7.1 0.4 45.0 3.1 80.8 61.6 44.3 0.5 13.9 9.2 13.7 20.2 5.9 32.1 68.2 15.0 24.0 2.9 4.8 306.8 0.6 35.7 7.5 76.8 281.2 27.6 8.1 50.5 16.0 2.9 35.3 33.1 9.7 188.3 12.8 5.0 152.6 16.8 176.4 21.5 30.7 1.9 193.6 5.1 4.6 0.7 2.5 3.6 202.4 0.0 2.2 0.0 0.5 1.6 0.2 0.0 0.1 0.1 3.9 0.0 0.4 0.5 0.0 0.0 0.5 2.9 0.1 0.7 107.0 98.6 83.4 119.7 82.4 88.5 96.4 95.5 99.3 87.0 116.2 94.7 1013.8 3.2 10.5 4.2 7.3 15.2 19.6 17.1 7.4 2.6 79.5 65.0 25.5 88.6 47.3 12.9 0.0 1.0 11.4 13.3 5.9 36.1 16.1 37.2 36.8 398.9 21.5 17.3 3.4 8.8 0.8 53.5 33.6 67.8 0.0 5.1 374.4 227.4 2.6 3.3 5.5 77.0 22.4 30.9 35.1 35.8 82.0 7.0 33.8 31.9 2.2 17.2 7.2 4.0 3.6 326.8 9.3 44.4 4.9 51.8 1.2 14.7 27.3 5.0 26.3 22.3 69.1 7.0 15.4 3.4 11.4 1.0 8.8 9.5 18.0 66.6 SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 53.8" "Group enriched" "Detected in some" 12 "Collecting duct cells: 25.8;Gastric mucus-secreting cells: 54.0" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;OE19: 6.8;RT4: 4.1" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Low region specificity" "Detected in single" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" 0.0 0.0 0.4 0.1 0.5 0.8 0.2 0.7 0.7 0.3 0.0 0.0 2.0 0.1 0.1 1.5 0.1 1.2 0.6 0.4 0.4 8.6 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 1.3 0.5 1.4 0.4 0.0 0.0 0.0 0.2 53.8 0.3 0.2 0.1 0.1 0.0 0.5 0.4 0.1 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 1.3 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.5 6.8 0.2 0.0 0.2 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.7 0.7 0.4 0.4 0.1 0.1 0.2 0.0 0.2 0.6 0.0 3.2 3.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.0 0.9 25.8 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 54.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.1 0.4 0.0 0.3 0.3 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLC9B2 "FLJ23984, NHA2, NHEDC2" ENSG00000164038 "Solute carrier family 9 member B2" Q86UD5 4 103019868-103085829 "Predicted membrane proteins, Transporters" "Antiport, Hydrogen ion transport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 38.7" "Cell type enhanced" "Detected in many" "Excitatory neurons: 57.9;Exocrine glandular cells: 68.5;Inhibitory neurons: 57.2;Pancreatic endocrine cells: 94.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 11.8" "Group enriched" "Detected in many" 5 "B-cells: 5.1;NK-cells: 11.8;T-cells: 6.4" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA047008 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 15: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Cell Junctions" "HPA047008: AB_2679901" "unprognostic (1.85e-1)" "unprognostic (5.43e-2)" "unprognostic (2.68e-1)" "unprognostic (1.11e-1)" "unprognostic (8.83e-2)" "unprognostic (1.23e-1)" "unprognostic (1.43e-2)" "unprognostic (3.78e-2)" "unprognostic (3.26e-1)" "unprognostic (2.53e-2)" "unprognostic (3.53e-2)" "unprognostic (1.67e-1)" "unprognostic (2.51e-5)" "unprognostic (2.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.90e-2)" "unprognostic (2.35e-5)" 7.8 6.0 11.2 5.2 11.7 4.6 5.7 10.9 12.8 6.2 3.2 6.2 1.1 6.8 2.3 3.4 5.6 7.6 6.2 12.5 11.1 2.5 38.7 3.6 5.9 11.4 9.1 6.7 2.4 0.3 8.5 3.9 12.7 4.1 2.7 12.8 2.4 5.0 3.0 3.0 3.7 7.7 7.0 3.6 4.9 3.6 10.0 3.6 2.9 3.5 5.6 6.5 4.9 11.2 4.9 2.1 5.2 10.5 26.0 20.7 0.0 22.0 7.8 3.2 3.0 2.5 3.0 29.3 3.7 24.3 5.1 1.4 12.2 9.3 4.8 24.7 7.5 30.2 7.5 21.8 13.5 22.5 8.8 18.7 10.8 7.7 27.3 11.1 15.3 8.3 10.1 22.1 10.7 1.7 15.3 10.8 4.4 0.1 6.4 0.0 6.0 12.2 9.0 2.4 17.5 14.9 10.0 2.3 6.0 1.4 2.6 13.4 17.6 7.5 4.3 11.6 6.9 16.8 14.2 21.7 8.7 17.5 3.0 0.0 0.1 0.0 4.9 0.0 6.4 5.1 5.1 4.1 0.9 3.0 3.1 3.8 0.0 11.8 0.1 1.6 2.4 1.8 11.2 11.7 10.9 12.8 12.5 11.1 11.4 9.1 12.7 7.0 10.0 11.2 13.9 0.0 0.5 15.0 15.6 4.8 3.4 2.0 6.2 9.7 3.1 2.8 2.5 8.6 1.1 0.0 27.1 0.5 6.5 0.2 0.0 14.1 12.1 1.1 8.6 17.8 3.0 17.2 57.9 68.5 2.3 13.2 22.4 0.9 1.3 10.3 6.1 39.5 1.4 8.4 57.2 1.1 4.1 1.3 5.3 6.9 5.6 3.4 10.6 5.6 3.9 0.7 0.0 32.6 17.6 94.7 0.3 5.3 12.0 4.9 0.0 1.4 1.1 2.3 6.6 16.5 11.5 5.8 4.2 5.6 3.8 0.3 7.9 4.8 0.3 1.3 SLC9C2 "MGC43026, SLC9A11" ENSG00000162753 "Solute carrier family 9 member C2 (putative)" Q5TAH2 1 173500460-173603072 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;choroid plexus: 1.9;testis: 6.0" "Cell type enriched" "Detected in some" 4 "Astrocytes: 27.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA059122, HPA079529" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nuclear speckles" "HPA059122: , HPA079529: " "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (8.52e-2)" "unprognostic (5.88e-3)" "unprognostic (3.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-3)" "unprognostic (1.19e-1)" "unprognostic (4.21e-2)" "unprognostic (4.92e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-6)" "unprognostic (1.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.98e-1)" "unprognostic (1.81e-1)" 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.2 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 1.3 1.2 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.5 0.2 0.2 0.5 0.3 1.3 1.2 0.8 0.8 0.4 0.6 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 1.3 0.0 6.2 0.1 1.3 0.1 0.0 0.1 6.2 1.7 0.1 0.4 0.0 0.0 5.0 0.0 0.5 0.3 0.0 0.1 0.0 0.5 0.4 1.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.7 0.0 0.7 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.1 0.1 5.4 0.4 0.0 0.0 0.1 0.0 1.3 0.0 0.0 SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 82.0;choroid plexus: 28.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 487.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 16.7;RPMI-8226: 12.0;SuSa: 16.1;U-266/70: 23.1;U-266/84: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" 0.0 0.1 48.9 0.1 65.9 0.1 4.0 43.5 80.2 0.0 28.6 0.1 0.0 0.1 0.2 0.1 0.3 0.2 0.9 41.3 46.4 1.2 11.5 2.8 0.7 54.0 51.9 0.2 2.4 0.2 0.4 1.2 52.6 0.7 0.0 0.6 15.8 0.0 0.4 0.5 0.1 0.0 45.2 0.5 0.3 1.9 48.3 0.6 0.2 0.0 0.4 0.2 0.0 82.0 2.1 0.6 0.8 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 3.8 1.4 0.1 2.1 0.2 0.0 0.3 0.3 0.2 0.5 0.7 0.9 0.0 0.5 1.5 0.0 0.4 0.3 0.0 1.7 0.2 0.2 1.5 0.1 0.4 4.0 1.2 0.0 2.6 0.4 0.1 16.7 2.0 0.2 0.2 0.2 12.0 0.0 2.2 1.9 2.9 0.0 0.2 0.2 16.1 3.2 0.9 0.0 0.1 1.7 0.8 0.4 23.1 9.8 0.2 0.1 0.3 0.0 0.2 0.1 0.1 0.4 0.1 0.6 0.4 0.6 0.4 0.0 0.2 0.6 0.4 1.3 0.3 0.0 0.2 0.5 0.1 48.9 65.9 43.5 80.2 41.3 46.4 54.0 51.9 52.6 45.2 48.3 82.0 0.0 35.3 3.1 5.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 2.8 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.8 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 102.1 0.0 0.1 0.0 2.5 487.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 614 "liver: 537.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 83.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 52.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NTERA-2: 1.3;RPMI-8226: 1.8;SuSa: 2.2" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA050892: AB_2681265, HPA073093: " "unprognostic (5.45e-1)" "unprognostic (1.82e-4)" "unprognostic (2.43e-3)" "unprognostic (1.96e-3)" "unprognostic (1.80e-1)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (5.63e-2)" "unprognostic (3.86e-2)" "unprognostic (3.49e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 537.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 83.1 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 265.1" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 203.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 65.3;A549: 17.5;CAPAN-2: 12.6;GAMG: 13.6;HeLa: 14.2;PC-3: 17.3;U-2 OS: 14.7" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA004943: AB_1854758, HPA050892: AB_2681265" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (7.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.54e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (2.36e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.0 16.2 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.0 0.5 0.0 0.0 265.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 65.3 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.6 0.0 4.3 0.0 13.6 0.1 0.0 0.5 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 14.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 203.4 0.0 0.0 0.5 0.0 0.0 1.6 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.2 SLCO4A1 "OATP-E, OATP4A1, SLC21A12" ENSG00000101187 "Solute carrier organic anion transporter family member 4A1" Q96BD0 20 62642503-62685785 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 57.2" "Cell type enhanced" "Detected in many" "Adipocytes: 61.8;Extravillous trophoblasts: 239.4;Melanocytes: 60.5" "Cancer enhanced" "Detected in all" "colorectal cancer: 21.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "PC-3: 197.2;RPTEC TERT1: 193.9" "Region enriched" "Detected in some" 5 "cerebellum: 6.7" "Low region specificity" "Detected in some" "HPA030669, HPA030670" Uncertain Supported "Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 38: Extravillous trophoblasts - Unknown function" "Cell Junctions" "HPA030669: AB_10601163, HPA030670: AB_10670033" "unprognostic (8.94e-2)" "unprognostic (2.01e-1)" "unprognostic (3.41e-1)" "unprognostic (2.46e-3)" "unprognostic (3.34e-2)" "unprognostic (1.12e-1)" "unprognostic (2.84e-3)" "prognostic unfavorable (4.74e-4)" "unprognostic (4.94e-2)" "unprognostic (1.21e-2)" "unprognostic (3.49e-3)" "unprognostic (1.53e-1)" "unprognostic (1.49e-1)" "unprognostic (2.84e-3)" "unprognostic (9.27e-2)" "unprognostic (1.53e-1)" "unprognostic (1.25e-1)" 32.4 5.6 26.2 1.8 24.0 1.3 23.4 24.2 35.7 11.1 19.6 9.8 1.2 8.7 0.3 16.7 13.1 1.8 48.6 23.9 25.4 35.8 5.0 57.2 2.4 26.5 24.8 6.5 4.9 3.8 2.9 4.7 28.0 5.9 1.8 21.5 8.5 1.0 18.8 25.6 9.2 0.8 25.7 6.6 13.5 2.1 31.6 1.1 8.6 5.6 3.2 12.0 16.8 24.9 14.8 19.1 0.8 10.8 2.5 2.1 26.5 4.7 16.6 14.1 5.4 32.0 14.9 17.8 44.2 0.5 9.6 22.0 16.4 1.0 5.4 2.1 9.6 21.7 22.1 23.8 0.1 16.6 6.7 0.0 6.5 0.3 6.2 4.2 2.5 10.7 17.1 4.6 0.0 14.8 17.2 63.9 5.4 74.1 197.2 30.6 1.1 26.2 193.9 14.2 17.4 25.1 4.1 4.4 15.7 6.5 1.0 7.5 2.8 0.4 10.5 7.0 27.2 9.2 15.9 11.1 38.1 24.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.1 0.0 0.9 0.7 0.2 0.1 0.0 0.0 0.0 0.0 1.6 0.2 26.2 24.0 24.2 35.7 23.9 25.4 26.5 24.8 28.0 25.7 31.6 24.9 61.8 3.2 1.3 1.3 13.1 27.3 1.4 19.8 1.2 14.1 1.2 0.8 4.4 1.5 5.9 25.8 31.3 2.1 3.7 7.5 0.0 5.9 0.3 8.7 3.6 40.3 0.0 2.1 7.9 2.5 239.4 4.3 20.9 35.6 0.0 0.0 14.6 0.6 5.5 0.0 6.6 8.4 2.0 9.7 33.5 0.7 0.3 11.9 60.5 3.7 0.0 6.1 0.0 1.5 0.3 11.8 1.9 0.7 19.1 3.5 0.8 9.6 1.3 43.2 0.0 1.9 2.9 0.2 3.0 1.1 16.1 23.5 5.6 0.1 7.5 11.0 SLCO4C1 "OATP-H, OATP4C1, OATPX, SLC21A20" ENSG00000173930 "Solute carrier organic anion transporter family member 4C1" Q6ZQN7 5 102233986-102296284 "Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "kidney: 41.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 49.7;Early spermatids: 21.6;NK-cells: 26.8;Proximal tubular cells: 32.8" "Cancer enriched" "Detected in many" 5 "renal cancer: 22.4" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 9.5;neutrophil: 9.8" "Group enriched" "Detected in many" 5 "granulocytes: 9.8;NK-cells: 2.6;T-cells: 3.8" "Cell line enhanced" "Detected in some" "Karpas-707: 17.5;RPTEC TERT1: 98.8;U-937: 25.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA058249 Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA058249: " "unprognostic (1.63e-2)" "unprognostic (2.47e-2)" "unprognostic (4.48e-4)" "unprognostic (5.70e-6)" "unprognostic (7.43e-2)" "unprognostic (7.71e-3)" "unprognostic (3.24e-3)" "unprognostic (2.05e-3)" "unprognostic (2.13e-1)" "unprognostic (7.12e-2)" "unprognostic (3.87e-3)" "unprognostic (5.83e-2)" "prognostic favorable (1.12e-4)" "unprognostic (3.29e-2)" "unprognostic (1.07e-1)" "unprognostic (5.91e-2)" "unprognostic (8.22e-2)" 0.4 0.8 0.2 0.6 0.3 8.6 0.5 0.0 0.4 0.3 0.0 1.0 2.2 0.1 0.2 0.1 0.2 2.3 0.3 0.2 0.0 41.6 7.6 7.8 0.5 0.2 0.0 0.1 0.4 0.1 0.2 0.1 0.2 0.0 0.8 0.1 2.0 3.6 0.1 0.3 1.5 0.1 0.0 1.3 0.6 0.8 0.3 1.0 1.6 0.1 0.2 0.2 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.7 1.1 0.0 1.0 0.2 1.8 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 17.5 0.0 1.3 0.1 0.3 0.8 0.0 0.0 0.0 0.0 1.2 98.8 0.1 0.7 0.5 0.0 0.3 0.0 2.3 0.0 2.4 0.0 0.0 0.7 0.0 0.0 1.6 0.0 0.0 0.0 25.8 0.1 9.5 1.0 7.3 3.8 0.0 0.3 0.0 0.6 2.1 0.4 0.1 0.2 1.3 9.8 2.6 0.0 0.2 0.0 1.0 0.2 0.3 0.0 0.4 0.2 0.0 0.2 0.0 0.2 0.0 0.3 0.3 0.1 6.4 49.7 0.3 0.6 0.0 0.1 1.2 0.0 0.0 1.8 0.3 0.3 1.5 6.4 5.5 0.0 0.0 9.6 1.4 1.9 0.2 21.6 0.0 0.1 0.3 0.0 5.7 9.1 0.8 0.0 0.3 0.0 1.6 5.7 0.0 0.4 11.0 0.2 0.0 6.6 0.1 2.0 0.6 0.3 2.6 0.3 2.4 0.0 1.0 3.2 0.0 26.8 1.5 0.3 0.3 0.1 0.0 1.4 0.0 1.8 32.8 3.1 0.0 0.0 0.1 0.1 2.5 2.4 0.0 0.0 0.0 3.4 0.1 1.1 0.4 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 32.5;pituitary gland: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.0;Excitatory neurons: 96.2;Inhibitory neurons: 34.6;Late spermatids: 25.5;Oligodendrocyte precursor cells: 25.1" "Group enriched" "Detected in many" 4 "glioma: 9.2;thyroid cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 23.2;MOLT-4: 81.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA006879: AB_1078197" "unprognostic (2.72e-1)" "unprognostic (2.25e-2)" "unprognostic (5.67e-3)" "unprognostic (1.43e-5)" "unprognostic (8.40e-2)" "unprognostic (2.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.81e-2)" "unprognostic (3.53e-1)" "unprognostic (6.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.66e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.39e-3)" 0.4 0.1 28.6 0.2 32.5 0.2 0.1 0.0 29.8 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.1 28.7 5.2 0.1 0.1 0.2 0.1 0.0 2.1 0.1 0.6 0.1 13.5 0.0 0.0 0.3 0.1 0.8 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.3 1.8 14.1 2.4 2.5 0.0 0.1 0.1 0.1 7.4 0.0 0.1 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.1 0.3 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 23.2 0.0 0.6 0.0 0.2 81.0 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 4.9 2.1 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.6 32.5 0.0 29.8 28.7 5.2 0.0 2.1 0.0 1.6 14.1 7.4 0.2 0.0 0.0 6.5 0.5 0.0 0.1 0.0 0.0 3.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 27.0 0.5 0.1 0.1 1.8 0.0 96.2 0.0 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.5 0.0 34.6 0.0 0.0 0.3 0.0 25.5 0.0 0.3 0.0 2.8 0.2 0.1 0.0 25.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.1 0.2 3.4 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 SLIT3 "MEGF5, SLIL2, Slit-3, SLIT1, slit2" ENSG00000184347 "Slit guidance ligand 3" O75094 5 168661733-169301139 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.3;Fibroblasts: 112.7;Sertoli cells: 85.5;Smooth muscle cells: 99.3" "Cancer enhanced" "Detected in many" "thyroid cancer: 12.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 1.2" "Lineage enriched" "Detected in single" 8 "NK-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 310.3;fHDF/TERT166: 116.0;RT4: 101.1;SH-SY5Y: 73.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051630 Approved Supported "Cell Junctions" "Secreted in other tissues" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Cell Junctions" "HPA051630: AB_2681557" "unprognostic (2.86e-2)" "unprognostic (2.64e-1)" "unprognostic (4.43e-2)" "unprognostic (2.92e-2)" "unprognostic (2.50e-2)" "unprognostic (3.53e-2)" "unprognostic (9.21e-3)" "unprognostic (3.06e-2)" "unprognostic (1.71e-1)" "unprognostic (9.50e-3)" "unprognostic (1.57e-1)" "unprognostic (2.08e-1)" "prognostic unfavorable (2.45e-5)" "unprognostic (5.90e-3)" "unprognostic (8.56e-2)" "unprognostic (4.27e-1)" "unprognostic (3.53e-1)" 61.9 20.7 10.0 11.9 10.6 0.1 32.7 11.9 7.5 36.4 0.3 20.0 5.4 23.9 8.8 21.4 22.2 43.5 39.7 12.3 4.3 16.7 1.5 38.1 6.2 12.9 0.7 17.0 7.8 44.9 4.4 21.7 11.6 10.3 9.7 3.1 16.8 15.4 4.4 25.8 10.4 27.1 0.3 14.3 10.1 2.7 6.9 20.0 23.3 6.5 4.2 55.5 24.3 2.2 0.0 11.0 0.1 0.0 310.3 5.7 0.0 18.1 3.1 4.0 8.4 0.1 0.0 0.0 4.2 116.0 13.1 0.0 2.9 1.2 0.3 0.0 0.3 0.0 0.0 0.0 0.9 0.0 0.0 1.8 4.2 0.5 3.9 44.1 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 101.1 1.1 73.3 0.0 0.0 0.0 12.5 0.0 0.0 0.0 3.0 1.9 25.5 0.1 0.0 0.0 0.0 6.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 10.0 10.6 11.9 7.5 12.3 4.3 12.9 0.7 11.6 0.3 6.9 2.2 11.7 0.0 2.3 4.2 0.5 26.6 1.8 5.5 3.4 8.6 1.1 3.8 25.9 0.0 0.4 0.0 0.0 2.3 0.5 0.0 0.0 0.2 11.9 1.3 35.7 5.4 0.0 0.0 202.3 0.0 0.5 112.7 4.6 3.6 1.3 0.5 1.8 0.0 1.2 0.0 20.2 0.0 0.0 0.0 32.5 8.2 0.9 1.1 35.6 14.0 0.0 13.7 0.0 8.0 2.9 0.0 0.0 0.4 0.8 1.1 0.1 1.9 0.2 0.9 85.5 1.8 99.3 1.2 2.2 1.1 17.6 1.1 1.8 0.3 0.0 0.8 SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.8;Bipolar cells: 41.7;Club cells: 27.4;Ionocytes: 16.2;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 28.8;OE19: 24.2;RT4: 101.4;WM-115: 23.7" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" 0.1 0.2 1.0 0.9 4.4 0.0 3.2 2.2 1.9 1.2 0.1 5.5 3.5 1.0 2.5 1.9 0.5 1.4 1.5 0.2 2.0 0.1 0.9 3.3 0.0 0.6 2.3 0.0 0.2 0.0 0.1 0.9 0.9 7.6 6.8 4.8 27.7 2.2 0.0 5.6 5.7 0.4 0.3 0.1 1.5 0.3 5.7 0.2 0.3 0.1 0.1 14.7 1.4 0.4 0.0 2.9 0.1 0.5 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.9 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 28.8 0.0 3.3 2.7 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 24.2 1.9 0.2 0.0 0.0 0.0 101.4 1.0 1.2 0.5 0.1 0.1 1.7 0.5 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.4 2.2 1.9 0.2 2.0 0.6 2.3 0.9 0.3 5.7 0.4 0.1 0.0 1.8 0.0 0.0 3.8 5.0 22.8 0.0 41.7 5.3 1.5 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 4.3 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.0 2.7 0.0 2.2 2.2 0.0 0.2 0.0 0.4 1.7 16.2 0.0 0.6 0.0 9.6 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 1.8 0.0 0.4 0.0 1.5 0.0 0.1 41.6 2.0 0.0 0.0 0.8 0.0 0.1 3.8 2.4 0.0 0.2 0.1 0.5 4.5 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967140-104029233 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 201.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 20.5 15.1 10.9 15.2 19.9 28.9 21.7 20.9 13.7 19.9 15.3 20.4 13.3 21.3 16.2 56.4 14.1 21.3 22.4 11.7 10.0 20.6 17.8 24.0 11.8 11.5 11.1 24.0 16.7 26.3 9.6 25.8 11.7 17.6 20.8 15.1 21.9 17.7 23.1 26.3 14.7 20.6 10.3 14.9 24.1 15.2 12.3 15.2 22.4 25.1 17.5 30.5 28.6 18.5 50.5 28.9 33.7 24.3 36.6 50.1 14.2 30.6 40.7 22.5 20.9 18.4 53.7 26.6 18.6 31.8 19.1 53.7 18.0 39.5 33.5 21.3 24.7 27.0 23.5 15.6 26.6 32.7 22.4 25.5 49.5 30.9 87.6 31.7 40.9 16.9 34.6 17.9 29.8 18.6 23.0 18.0 8.4 32.4 18.2 22.2 41.4 13.8 29.0 60.3 8.0 13.8 26.6 25.7 25.8 17.2 13.8 23.4 63.4 16.6 16.9 30.6 36.3 21.6 28.0 16.7 24.2 43.1 10.7 0.6 0.5 1.7 1.4 0.5 1.5 0.4 0.8 1.0 0.5 0.6 0.6 1.0 2.7 0.5 0.4 0.9 0.8 0.3 10.9 19.9 20.9 13.7 11.7 10.0 11.5 11.1 11.7 10.3 12.3 18.5 73.5 179.5 129.5 38.5 19.9 57.0 87.1 30.9 26.7 32.2 32.0 35.1 110.4 30.0 100.9 44.1 25.0 37.4 40.1 70.0 3.9 34.0 8.4 43.3 77.1 80.2 18.5 25.5 35.3 54.0 13.6 52.6 44.9 90.3 35.3 54.6 50.7 25.3 19.9 25.2 39.3 37.2 18.3 24.5 36.9 16.6 46.6 37.5 8.8 34.7 43.9 25.7 27.8 34.2 63.9 85.5 81.6 63.2 22.3 67.8 21.9 11.5 57.9 25.4 6.6 68.1 49.3 46.3 35.3 61.4 68.5 52.4 44.2 71.7 37.4 201.0 SLX4 "BTBD12, FANCP, KIAA1784, KIAA1987" ENSG00000188827 "SLX4 structure-specific endonuclease subunit" Q8IY92 16 3581181-3611606 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" "Fanconi anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.6" "Cell type enhanced" "Detected in many" "Spermatocytes: 20.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049421, HPA066238" Approved Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Cell Junctions, Cytosol" "HPA049421: AB_2680759, HPA066238: AB_2685642" "unprognostic (1.04e-1)" "unprognostic (1.23e-1)" "unprognostic (4.06e-2)" "unprognostic (2.65e-2)" "unprognostic (4.62e-1)" "unprognostic (6.08e-3)" "unprognostic (8.28e-5)" "unprognostic (6.52e-2)" "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.97e-2)" "unprognostic (1.50e-1)" "unprognostic (4.32e-2)" "unprognostic (8.39e-3)" "unprognostic (1.20e-1)" "unprognostic (1.43e-3)" "unprognostic (5.74e-2)" 1.8 2.1 2.1 2.9 1.9 3.0 1.6 7.1 2.7 2.1 0.4 2.3 2.2 2.1 1.3 2.4 2.0 1.1 1.9 2.3 2.1 1.9 1.9 2.1 4.1 2.3 2.0 1.6 1.7 1.1 3.9 1.1 1.8 2.3 0.9 1.7 1.6 1.0 2.7 1.8 2.8 1.2 1.1 3.4 2.2 10.6 1.9 2.7 1.8 1.3 2.9 2.1 2.0 2.1 2.7 8.4 5.3 6.7 2.0 2.1 5.6 4.3 2.2 4.9 5.4 4.2 3.3 10.0 4.2 2.2 3.8 6.0 3.6 3.0 2.9 8.4 4.6 6.8 6.5 2.7 1.8 6.7 9.3 1.5 2.2 4.6 2.6 1.2 3.6 5.6 6.7 5.3 3.9 4.7 4.2 5.9 4.5 1.7 3.1 8.2 8.9 2.8 1.9 1.9 4.5 4.1 3.8 2.6 1.3 2.8 6.5 5.2 4.3 5.6 7.8 4.9 5.1 4.8 4.0 11.4 1.8 6.7 5.7 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 2.1 1.9 7.1 2.7 2.3 2.1 2.3 2.0 1.8 1.1 1.9 2.1 2.7 0.0 2.3 4.6 4.5 0.8 0.8 1.1 4.0 8.7 2.0 1.4 1.7 1.5 3.2 0.0 2.1 1.7 3.4 2.0 0.0 1.5 6.5 5.5 4.2 1.8 0.0 6.5 9.5 2.4 1.6 2.4 3.6 4.6 0.0 4.8 1.1 1.4 2.9 0.0 9.3 2.4 2.0 2.9 1.6 2.3 2.1 5.1 0.0 4.7 2.2 2.7 4.1 7.1 5.5 2.0 0.3 1.9 4.0 0.4 2.3 0.6 2.3 10.1 0.0 4.9 2.5 20.0 9.1 2.3 0.6 1.0 4.4 3.0 2.1 0.6 SMAGP "hSMAGP, MGC149453, MGC149454" ENSG00000170545 "Small cell adhesion glycoprotein" Q0VAQ4 12 51244558-51270415 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 139.8;placenta: 102.1" "Group enriched" "Detected in many" 7 "Cytotrophoblasts: 1219.9;Syncytiotrophoblasts: 842.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 131.2;OE19: 163.9" "Low region specificity" "Detected in all" HPA039711 Enhanced Supported "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA039711: AB_10674985" "unprognostic (2.55e-3)" "unprognostic (2.63e-1)" "unprognostic (3.96e-2)" "unprognostic (3.63e-3)" "prognostic unfavorable (5.36e-4)" "unprognostic (3.01e-1)" "unprognostic (1.63e-3)" "unprognostic (6.26e-2)" "unprognostic (7.48e-2)" "unprognostic (9.11e-2)" "prognostic unfavorable (4.38e-4)" "unprognostic (1.46e-1)" "prognostic favorable (2.24e-4)" "unprognostic (4.32e-3)" "unprognostic (1.60e-1)" "unprognostic (1.99e-2)" "unprognostic (1.52e-1)" 14.0 17.2 2.7 9.9 2.7 3.5 16.1 5.2 3.2 33.8 3.4 57.5 17.6 6.5 20.7 139.8 8.3 16.2 10.3 3.0 2.5 43.0 10.2 17.7 6.0 2.8 2.9 11.4 16.5 11.1 4.3 102.1 2.8 10.5 59.3 1.0 24.1 8.6 3.4 34.8 19.6 8.5 2.6 13.7 35.9 8.1 3.3 1.5 8.7 6.8 27.6 17.5 67.9 3.0 81.6 24.2 2.9 2.7 10.5 40.9 131.2 61.1 60.9 30.6 18.7 48.9 83.2 1.0 10.5 37.9 11.6 28.3 17.1 23.5 42.6 4.1 14.2 10.9 3.3 16.5 28.8 2.7 10.1 26.7 17.8 66.3 59.4 69.4 74.6 20.6 8.7 4.7 49.9 71.4 13.4 9.8 12.3 163.9 93.9 0.8 0.8 3.1 44.0 18.5 3.3 4.1 13.4 53.2 10.2 31.3 45.0 4.2 26.1 33.9 32.7 1.7 37.8 1.7 2.4 1.6 49.8 26.3 18.7 4.6 6.6 12.0 15.4 4.6 10.0 36.9 6.8 11.1 4.7 38.1 6.3 11.0 16.0 19.8 5.4 2.9 5.3 6.8 2.7 2.7 5.2 3.2 3.0 2.5 2.8 2.9 2.8 2.6 3.3 3.0 44.1 0.0 25.7 0.3 26.3 21.7 74.3 35.5 12.0 1.3 23.4 25.8 1.7 55.8 44.7 16.5 0.0 1219.9 21.7 85.0 49.0 43.6 11.7 4.8 2.3 60.9 20.4 8.6 0.6 108.7 108.0 11.4 47.9 8.7 12.7 19.7 51.4 6.7 96.8 1.7 0.5 121.5 26.4 6.3 11.2 3.2 13.1 6.1 14.2 6.5 7.9 4.1 38.1 0.0 0.5 142.5 88.1 9.8 5.7 73.7 35.0 22.6 17.4 1.7 26.3 4.8 11.1 6.2 31.3 80.7 29.7 842.5 13.8 9.8 121.7 105.2 SMAP1 "FLJ13159, SMAP-1" ENSG00000112305 "Small ArfGAP 1" Q8IYB5 6 70667776-70862011 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 325.7;Late spermatids: 281.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030574 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA030574: AB_10601589" "unprognostic (1.55e-1)" "unprognostic (2.66e-3)" "unprognostic (1.01e-3)" "unprognostic (2.98e-3)" "unprognostic (7.06e-2)" "unprognostic (2.90e-2)" "unprognostic (1.66e-3)" "unprognostic (3.46e-1)" "unprognostic (6.50e-2)" "unprognostic (3.75e-2)" "unprognostic (7.80e-2)" "unprognostic (2.40e-2)" "unprognostic (1.32e-1)" "unprognostic (4.73e-2)" "unprognostic (6.08e-2)" "unprognostic (2.85e-1)" "unprognostic (1.22e-1)" 17.0 12.8 24.4 16.1 27.8 18.6 13.6 19.5 44.8 15.2 13.3 27.5 26.8 14.1 18.0 28.4 10.2 17.4 23.1 27.6 24.3 14.1 16.6 14.9 15.4 22.7 25.3 11.1 37.2 28.5 8.6 16.1 23.7 17.6 28.3 24.8 18.0 15.2 32.9 20.4 26.7 19.7 20.1 13.7 20.9 30.9 24.4 24.8 21.1 20.1 22.4 18.1 16.1 29.2 60.3 18.6 28.5 35.3 26.0 33.9 46.4 26.6 29.5 21.4 20.9 27.9 17.4 31.4 28.1 32.0 30.5 18.5 27.4 28.1 35.5 36.3 39.4 34.7 16.5 23.6 17.2 25.5 28.0 22.3 31.3 24.2 29.2 39.6 34.2 16.1 33.8 36.9 33.8 35.0 19.2 31.4 21.3 30.9 21.9 36.0 107.9 51.8 38.1 36.0 40.7 28.7 16.9 23.3 17.1 24.2 31.0 37.3 33.6 17.2 29.7 11.4 23.5 34.3 32.9 16.0 13.0 29.4 24.2 35.0 16.4 18.4 18.2 18.3 20.7 14.8 24.3 21.0 14.0 12.7 12.1 15.7 22.6 25.6 20.0 13.7 25.3 23.4 24.4 27.8 19.5 44.8 27.6 24.3 22.7 25.3 23.7 20.1 24.4 29.2 45.0 38.5 39.4 58.1 39.3 66.9 37.7 66.9 33.0 51.8 39.6 47.2 38.8 52.9 46.0 38.6 37.5 26.2 47.6 111.3 54.8 78.9 325.7 26.1 46.8 43.2 41.9 28.8 120.1 151.0 48.8 40.3 64.7 52.1 48.2 42.9 58.5 41.3 56.6 55.5 104.3 82.3 61.1 61.2 59.8 281.1 50.7 53.0 32.0 60.0 64.1 69.7 64.9 115.6 72.7 108.2 99.5 67.0 51.8 76.3 92.6 69.6 21.1 38.6 65.7 36.3 53.3 105.2 84.2 89.3 77.3 31.7 64.9 44.1 75.8 51.6 SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.4;kidney: 3.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Collecting duct cells: 1.8;Distal tubular cells: 5.9;Erythroid cells: 2.7;Hepatic stellate cells: 4.6;Proximal tubular cells: 7.3" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "HPA040574: AB_2677026, HPA047804: AB_2680160" "unprognostic (1.16e-1)" "unprognostic (2.09e-4)" "unprognostic (2.40e-4)" "unprognostic (5.10e-2)" "unprognostic (3.88e-2)" "unprognostic (6.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (1.48e-8)" "unprognostic (2.85e-1)" "unprognostic (7.53e-3)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" 0.5 0.4 0.0 0.1 0.2 0.3 0.2 0.1 0.1 3.4 0.3 0.2 0.0 0.3 0.1 0.0 0.3 1.8 0.9 0.1 0.2 3.0 1.5 1.1 0.5 0.1 0.2 0.2 0.2 0.5 0.2 1.1 0.1 0.8 0.1 1.3 0.1 1.6 0.1 0.1 0.1 0.1 0.1 1.8 0.1 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 1.9 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.5 2.8 0.0 1.8 0.0 0.1 0.0 0.0 5.9 0.2 0.0 0.0 0.2 0.3 0.0 2.7 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 4.6 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 SMG9 "C19orf61, FLJ12886" ENSG00000105771 "SMG9 nonsense mediated mRNA decay factor" Q9H0W8 19 43727983-43754962 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Nonsense-mediated mRNA decay" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 103.2;Late spermatids: 329.5;Syncytiotrophoblasts: 95.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041763, HPA042096" Uncertain Approved "Plasma membrane,Mitochondria,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 78: Testis - Spermatogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Mitochondria, Cytosol" "Plasma membrane" "HPA041763: AB_2677659, HPA042096: AB_2677845" "unprognostic (2.22e-1)" "unprognostic (1.32e-1)" "unprognostic (7.41e-2)" "unprognostic (6.46e-2)" "unprognostic (2.71e-1)" "unprognostic (1.55e-2)" "prognostic unfavorable (2.15e-5)" "unprognostic (2.71e-1)" "unprognostic (4.11e-2)" "unprognostic (9.24e-3)" "unprognostic (3.88e-2)" "unprognostic (8.76e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (8.00e-2)" "unprognostic (1.27e-1)" "unprognostic (2.36e-1)" "prognostic favorable (8.09e-4)" 9.0 11.7 10.3 10.9 10.8 8.4 8.7 10.9 13.5 10.6 5.9 9.0 8.0 9.0 7.7 9.2 7.7 6.8 7.7 10.2 10.6 7.7 6.6 10.0 13.0 13.1 11.6 7.8 5.8 8.8 9.4 10.1 13.6 11.5 6.2 5.9 12.0 6.9 7.5 10.7 10.0 8.1 9.5 13.5 8.7 33.8 11.6 11.8 8.3 7.1 12.0 10.0 9.9 14.9 25.3 27.2 19.5 12.5 13.4 18.9 13.1 35.1 20.8 38.4 28.7 19.4 32.5 27.4 16.9 24.1 13.2 10.7 22.9 19.7 24.9 21.1 13.2 49.2 20.5 12.9 15.6 37.4 25.9 10.1 16.6 27.9 29.6 32.1 15.8 25.0 37.7 23.6 18.0 17.9 39.9 10.6 9.4 48.0 18.2 21.2 16.1 12.3 20.4 20.4 32.4 15.9 36.7 27.4 21.3 15.4 16.6 20.5 19.2 59.7 35.4 22.3 27.1 11.5 26.8 33.4 17.9 28.4 49.7 1.0 5.3 3.3 5.1 7.7 4.5 7.4 5.1 4.3 6.9 5.3 6.7 4.5 1.3 4.2 11.7 6.1 4.1 11.3 10.3 10.8 10.9 13.5 10.2 10.6 13.1 11.6 13.6 9.5 11.6 14.9 7.7 32.1 8.3 20.9 13.7 9.3 15.0 16.8 11.4 13.2 10.0 11.0 4.4 4.3 9.0 9.2 4.2 49.5 11.3 9.5 1.9 12.2 103.2 5.5 7.0 12.0 4.2 7.8 19.5 8.7 15.8 11.4 15.8 8.9 9.5 12.1 11.0 3.3 21.4 13.5 23.0 11.3 8.2 10.3 9.2 329.5 13.1 12.1 10.6 11.2 16.2 6.0 4.1 16.1 29.6 13.6 9.2 12.0 11.2 15.9 8.5 6.8 8.4 9.2 6.6 11.2 8.5 42.6 16.2 8.4 7.1 95.4 9.3 11.8 12.2 11.1 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMPD2 "ISC1, nSMase" ENSG00000135587 "Sphingomyelin phosphodiesterase 2" O60906 6 109440724-109443919 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Lipid metabolism, Sphingolipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 53.0" "Cell type enhanced" "Detected in many" "Early spermatids: 179.4;Late spermatids: 359.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018110, HPA018125" Uncertain Approved "Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Cell Junctions" "HPA018110: AB_1857292, HPA018125: AB_1857293" "unprognostic (1.61e-1)" "unprognostic (8.01e-2)" "unprognostic (1.97e-1)" "unprognostic (8.79e-3)" "unprognostic (3.88e-2)" "unprognostic (2.38e-1)" "prognostic unfavorable (1.17e-4)" "unprognostic (7.08e-2)" "unprognostic (7.59e-2)" "unprognostic (1.41e-1)" "prognostic favorable (1.00e-3)" "unprognostic (3.60e-2)" "unprognostic (2.14e-3)" "unprognostic (7.94e-2)" "unprognostic (2.25e-1)" "unprognostic (1.45e-2)" "prognostic favorable (1.70e-4)" 6.9 8.8 7.6 8.6 7.4 12.7 10.5 9.6 7.8 12.6 15.1 12.7 13.5 7.1 15.5 24.5 21.4 8.7 6.7 7.7 6.9 12.2 7.6 9.7 13.3 7.6 7.9 8.2 17.7 22.1 11.1 6.0 7.2 13.2 12.6 6.5 15.6 5.8 4.1 21.7 12.3 4.9 7.6 13.3 14.2 53.0 7.0 10.3 13.3 1.7 17.1 10.4 14.3 8.8 13.1 14.8 7.7 12.2 13.2 7.1 25.5 4.3 15.7 10.5 9.8 14.0 10.3 7.1 9.0 9.3 22.1 16.4 7.8 18.7 6.3 9.1 20.5 8.2 15.9 8.7 11.0 9.1 9.4 7.7 21.3 9.3 18.4 11.8 9.8 12.4 16.3 12.2 5.3 18.7 14.8 19.7 2.1 17.3 7.5 10.4 3.6 7.7 19.3 21.8 10.1 8.4 8.2 24.9 19.3 6.2 7.9 17.2 6.3 4.7 6.8 3.8 16.3 8.3 2.3 4.6 9.1 8.6 8.5 6.2 9.0 10.8 6.9 8.6 7.8 14.4 7.8 8.2 11.2 20.4 5.6 5.9 2.5 7.3 7.8 14.3 8.2 6.0 7.6 7.4 9.6 7.8 7.7 6.9 7.6 7.9 7.2 7.6 7.0 8.8 3.9 12.8 7.2 1.6 15.9 9.8 12.9 13.8 8.6 1.3 8.9 6.7 2.1 7.2 11.8 12.9 4.2 10.3 9.1 26.1 1.9 19.2 179.4 28.4 4.0 4.4 8.4 4.2 1.4 19.8 18.5 6.1 25.0 4.3 0.0 3.5 3.6 3.6 9.5 0.0 0.5 27.1 14.2 4.1 11.2 359.7 9.3 7.2 8.8 2.8 9.9 3.7 6.2 0.0 1.7 15.4 27.7 9.1 9.8 15.0 37.5 9.3 67.1 4.9 13.1 3.1 5.8 69.9 10.9 13.8 18.6 17.0 7.6 8.7 17.8 16.9 SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "heart muscle: 757.5;skeletal muscle: 1183.4;tongue: 1097.5" "Cell type enriched" "Detected in some" 22 "Cardiomyocytes: 807.6" "Group enriched" "Detected in many" 4 "head and neck cancer: 7.2;stomach cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "GAMG: 23.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077360 Approved "Plasma membrane" NA NA 62000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA077360: AB_2732342" "unprognostic (7.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.39e-2)" "unprognostic (7.46e-2)" "unprognostic (5.27e-1)" "unprognostic (1.96e-2)" "unprognostic (3.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (2.82e-1)" "unprognostic (8.38e-2)" 0.2 0.1 2.6 0.5 2.4 0.1 1.1 3.6 3.8 0.3 0.9 25.6 0.7 0.4 0.0 20.0 0.7 0.5 757.5 1.6 4.1 0.1 1.2 0.5 0.2 1.7 3.3 1.1 0.2 0.0 0.2 0.0 1.5 11.1 3.4 1.7 17.8 0.7 1183.4 0.5 4.1 12.6 1.3 0.1 7.2 0.2 5.3 1.5 0.2 1097.5 0.1 3.2 0.2 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 3.6 3.8 1.6 4.1 1.7 3.3 1.5 1.3 5.3 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 807.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.6 0.0 0.0 16.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 35.6 9.5 0.1 0.3 0.0 0.0 0.3 0.1 2.1 0.1 0.0 SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 675.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane" NA NA 3900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB037083: AB_477494, CAB037317: AB_261925, HPA001214: AB_1080037" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.76e-3)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (9.67e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (8.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" 44.4 30.3 23.0 62.9 27.7 35.1 38.2 25.7 46.3 37.5 28.6 52.8 50.3 43.2 35.3 31.9 29.8 40.2 44.6 23.5 24.8 42.4 44.4 45.2 84.6 28.0 25.9 34.6 24.2 36.2 12.9 68.9 31.3 49.2 51.2 12.8 45.2 30.9 43.9 26.5 56.4 48.3 25.6 70.3 39.9 36.1 27.5 38.0 33.1 28.7 78.7 42.5 23.9 37.2 58.3 29.7 55.7 54.7 91.8 70.4 85.1 77.6 61.8 50.8 59.1 93.0 27.8 35.1 91.3 52.3 48.1 52.7 63.2 50.1 70.9 58.4 35.3 149.2 30.5 89.1 66.8 57.4 136.6 59.1 37.9 43.5 70.4 64.7 192.9 69.4 121.6 31.4 67.1 24.1 68.3 69.4 46.0 94.3 22.8 122.4 33.8 55.1 71.8 57.8 9.0 36.3 57.2 51.3 56.4 83.5 76.2 91.6 155.0 46.6 61.2 52.1 80.4 59.1 122.3 153.2 56.3 120.0 62.8 244.8 159.8 675.6 51.4 237.6 60.2 110.2 53.5 50.2 148.2 103.9 68.0 52.4 361.9 70.7 236.0 62.6 66.4 179.4 23.0 27.7 25.7 46.3 23.5 24.8 28.0 25.9 31.3 25.6 27.5 37.2 58.9 112.2 30.5 30.7 79.0 50.7 107.6 30.8 34.7 7.7 41.9 19.8 19.2 38.6 32.8 20.2 20.9 75.9 45.3 61.3 56.7 71.1 207.6 34.4 38.6 77.1 14.9 25.0 21.2 52.2 109.5 44.3 32.6 41.2 83.5 22.4 77.4 28.0 88.9 5.0 23.6 80.2 52.9 125.4 112.8 326.0 39.1 131.8 44.4 36.5 120.0 14.6 53.5 39.7 54.6 110.8 52.8 60.5 27.9 79.9 55.0 76.2 42.6 18.4 52.6 42.1 40.6 16.7 7.9 29.3 38.5 142.6 48.2 47.8 39.7 64.7 SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10218830-10307418 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 20 "brain: 1658.7;retina: 492.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 559.2;Excitatory neurons: 1015.8;Inhibitory neurons: 552.8;Rod photoreceptor cells: 254.4" "Cancer enriched" "Detected in many" 4 "glioma: 28.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 23.8;SCLC-21H: 78.2;SH-SY5Y: 46.6;U-87 MG: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane" NA NA 9000 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Vesicles "CAB000360: AB_2286342, HPA001830: AB_1080039, HPA071013: " "unprognostic (1.64e-3)" "unprognostic (7.26e-3)" "unprognostic (4.36e-2)" "unprognostic (2.49e-7)" "unprognostic (6.86e-3)" "unprognostic (5.87e-3)" "unprognostic (1.15e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (5.82e-3)" "unprognostic (4.80e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-3)" "unprognostic (2.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.02e-2)" 1.5 43.6 251.0 4.1 383.5 0.2 4.4 598.0 1658.7 0.8 0.0 5.7 3.7 7.9 12.9 0.5 7.7 2.3 3.2 420.4 142.2 1.4 1.0 1.8 0.4 427.4 24.7 6.9 6.3 1.2 54.3 0.6 386.6 3.2 2.3 492.0 0.5 19.6 0.8 0.7 3.9 8.1 38.1 0.2 6.3 3.6 147.6 0.5 0.7 0.1 0.4 1.1 1.6 726.9 0.0 4.7 3.9 0.0 0.4 0.1 0.0 2.0 0.0 4.8 1.4 0.0 0.0 0.0 4.3 0.0 3.4 0.8 0.6 0.0 9.6 0.5 0.3 0.0 6.8 0.7 3.5 0.0 0.5 4.4 0.0 3.9 0.0 10.7 0.0 2.8 0.0 23.8 1.6 0.0 0.0 0.0 0.8 3.0 0.0 0.0 0.0 0.1 0.9 0.0 78.2 46.6 0.7 0.1 0.0 2.4 0.0 6.5 0.0 5.0 6.8 0.0 2.3 0.1 12.9 0.1 56.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 251.0 383.5 598.0 1658.7 420.4 142.2 427.4 24.7 386.6 38.1 147.6 726.9 0.5 0.0 0.0 117.2 0.0 0.8 1.4 0.1 0.0 559.2 0.2 1.3 0.5 8.6 0.0 0.0 106.3 0.0 0.2 0.0 0.0 0.2 16.3 0.1 0.7 5.2 43.5 0.0 1015.8 0.0 0.1 3.9 0.0 0.2 0.0 0.6 0.0 0.2 0.1 65.6 552.8 3.4 0.0 0.0 0.4 83.3 17.1 0.1 1.8 120.9 0.0 71.9 0.0 179.4 113.3 1.0 2.6 68.8 0.0 0.6 0.1 3.0 0.0 254.4 0.0 0.0 1.3 1.1 0.4 0.0 0.9 0.0 0.0 2.6 0.1 0.1 SNRK "FLJ20224, HSNFRK, KIAA0096" ENSG00000163788 "SNF related kinase" Q9NRH2 3 43286512-43424764 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 126.0;TIME: 74.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042163 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane,Cell Junctions" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Vesicles, Plasma membrane, Cell Junctions" Nucleoplasm "HPA042163: AB_10794645" "prognostic favorable (9.28e-4)" "unprognostic (8.46e-2)" "unprognostic (2.79e-3)" "unprognostic (6.41e-2)" "unprognostic (1.14e-1)" "unprognostic (1.16e-3)" "unprognostic (2.00e-2)" "unprognostic (1.08e-1)" "unprognostic (2.63e-3)" "unprognostic (4.25e-1)" "unprognostic (2.32e-1)" "unprognostic (4.68e-2)" "prognostic favorable (9.41e-5)" "unprognostic (9.21e-3)" "unprognostic (2.04e-1)" "unprognostic (7.06e-3)" "unprognostic (7.38e-2)" 37.6 10.3 9.7 17.2 9.7 58.4 26.5 27.7 13.2 21.7 9.8 14.6 16.1 23.1 7.8 19.7 13.6 20.4 16.3 9.5 12.5 20.0 25.4 26.4 19.8 14.0 11.5 14.4 22.7 18.5 11.4 33.3 14.7 11.2 11.9 18.8 11.4 10.8 14.3 30.3 17.2 22.9 9.5 33.0 14.4 11.1 13.2 40.5 27.3 21.6 14.7 19.8 21.7 8.7 8.4 5.0 9.1 8.8 26.6 9.5 8.7 8.8 14.8 9.4 9.1 6.9 11.8 13.2 6.8 11.2 6.2 5.3 10.7 18.9 9.6 15.1 8.8 15.0 9.1 8.1 13.8 17.1 16.1 10.5 12.7 10.6 17.9 9.5 126.0 14.9 6.7 14.9 8.7 4.4 17.3 15.0 10.1 4.6 22.6 11.7 6.7 14.0 24.2 14.1 6.4 13.4 7.7 8.1 11.1 7.9 5.5 21.4 74.1 8.2 8.3 9.5 10.4 23.7 18.3 11.0 5.8 20.1 12.0 9.4 4.2 7.6 9.5 7.5 13.0 3.6 8.3 9.6 4.0 3.6 12.1 13.1 27.7 11.0 7.1 1.2 9.7 9.7 9.7 9.7 27.7 13.2 9.5 12.5 14.0 11.5 14.7 9.5 13.2 8.7 88.4 32.1 24.1 30.0 29.0 52.8 10.3 6.4 12.5 52.1 9.7 8.6 17.7 15.7 15.0 16.5 16.7 7.7 57.6 37.0 11.7 10.9 50.4 23.3 16.2 84.2 10.8 10.3 21.6 8.9 3.2 16.4 12.8 19.8 14.5 8.9 98.6 25.2 13.7 30.3 43.2 10.7 12.2 24.8 19.0 7.5 12.5 26.5 23.2 34.7 21.9 16.3 65.9 24.6 10.7 11.2 20.6 11.7 27.3 12.7 25.2 12.2 19.2 18.3 124.9 31.3 49.1 11.1 16.2 13.7 51.3 8.2 61.2 9.5 11.1 18.0 SNTB2 "D16S2531E, EST25263, SNT2B2, SNT3, SNTL" ENSG00000168807 "Syntrophin beta 2" Q13425 16 69187129-69309052 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.4;Muller glia cells: 214.1;Rod photoreceptor cells: 136.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "SiHa: 42.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001394 Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" Nucleoplasm "HPA001394: AB_1080170" "unprognostic (4.86e-1)" "unprognostic (3.26e-2)" "unprognostic (2.77e-2)" "unprognostic (8.07e-3)" "unprognostic (6.46e-2)" "unprognostic (9.68e-2)" "unprognostic (1.89e-2)" "unprognostic (5.50e-2)" "unprognostic (1.22e-2)" "unprognostic (1.63e-2)" "unprognostic (1.65e-2)" "unprognostic (3.64e-2)" "unprognostic (5.77e-3)" "unprognostic (1.71e-2)" "unprognostic (7.43e-2)" "unprognostic (1.73e-2)" "unprognostic (1.88e-1)" 11.0 5.0 3.3 5.2 3.9 2.7 8.8 1.0 6.7 11.0 10.1 6.7 3.7 10.4 5.1 7.0 8.7 7.1 5.3 4.6 0.8 6.7 3.8 8.6 5.6 2.5 0.9 6.2 4.1 12.4 4.0 5.2 0.9 8.2 5.3 21.6 5.2 5.5 5.7 8.5 6.0 8.7 0.6 5.7 6.1 7.1 1.5 5.8 10.5 3.8 4.9 8.7 8.7 3.7 7.2 10.9 7.4 5.8 26.6 35.6 9.1 13.9 19.3 10.7 11.8 10.7 6.5 9.0 8.3 16.2 5.6 12.9 10.0 6.8 13.9 4.0 5.5 4.0 11.1 9.2 8.8 0.3 5.9 25.6 4.9 17.6 7.1 11.1 32.4 2.5 2.3 13.8 13.1 8.2 3.0 1.4 5.0 4.2 8.6 18.1 6.5 16.8 5.7 10.9 2.8 6.1 42.6 6.0 4.4 5.5 7.1 0.5 25.4 20.0 9.6 14.2 13.0 3.1 5.2 10.0 12.8 1.4 9.3 0.4 0.2 0.3 0.9 0.3 0.9 0.2 0.4 0.5 0.2 0.2 0.2 1.1 0.9 0.7 0.3 0.1 0.5 0.3 3.3 3.9 1.0 6.7 4.6 0.8 2.5 0.9 0.9 0.6 1.5 3.7 55.9 19.2 11.7 36.6 9.0 38.0 28.0 17.1 70.0 33.2 19.0 25.0 9.2 10.0 10.4 27.6 41.7 9.5 33.7 29.0 3.9 9.7 25.9 20.6 61.3 81.4 10.3 4.8 151.4 24.1 7.9 53.1 20.9 28.7 1.3 15.8 126.7 11.1 6.9 5.0 62.6 16.6 8.2 33.1 29.3 27.5 59.0 12.9 30.2 33.7 8.6 214.1 47.4 30.7 27.9 16.3 32.8 65.1 20.7 40.9 12.7 34.5 10.0 136.7 6.6 26.0 35.6 27.9 15.4 30.7 38.8 3.7 32.8 20.2 19.6 28.7 SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 68.2;Excitatory neurons: 24.4;Horizontal cells: 90.9;Late spermatids: 44.7;Spermatocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HAP1: 1.7;JURKAT: 1.6;MOLT-4: 1.1;NTERA-2: 2.0;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" 2.0 0.3 0.6 0.0 0.7 0.0 1.8 1.0 0.6 1.0 1.1 0.5 0.1 1.2 0.2 0.5 1.2 0.2 0.4 1.7 0.7 0.1 0.0 0.3 0.0 1.7 0.9 0.2 0.9 0.0 2.9 0.0 1.3 0.6 0.2 2.1 0.5 0.0 0.4 1.1 0.6 0.7 0.4 3.2 0.3 1.8 0.7 0.2 0.7 0.9 0.1 0.8 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.0 0.6 1.7 0.7 1.7 0.9 1.3 0.4 0.7 0.6 6.8 0.0 0.0 0.7 0.4 0.9 0.1 0.0 0.6 0.8 0.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.2 0.1 0.9 7.3 0.0 0.0 24.4 0.2 0.5 0.8 0.0 0.0 0.0 3.0 0.0 0.0 0.1 90.9 10.7 0.0 0.0 0.0 1.2 44.7 0.3 0.0 1.8 9.4 0.0 0.6 0.0 1.5 1.3 0.0 0.0 4.1 0.0 0.3 0.0 0.5 0.0 4.6 0.0 0.3 0.4 22.0 5.4 0.1 0.1 0.0 0.2 0.2 0.0 0.2 SNX15 ENSG00000110025 "Sorting nexin 15" Q9NRS6 11 65027439-65040572 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Distal enterocytes: 5.6;Enteroendocrine cells: 7.8;granulocytes: 8.2;monocytes: 7.9;Paneth cells: 8.0;Proximal enterocytes: 6.5;Undifferentiated cells: 5.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038955 Approved Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoli, Cytosol" "Vesicles, Plasma membrane" "HPA038955: AB_10672834" "unprognostic (2.00e-2)" "unprognostic (4.90e-2)" "unprognostic (3.93e-1)" "unprognostic (9.61e-4)" "unprognostic (2.79e-1)" "unprognostic (4.06e-3)" "unprognostic (4.45e-3)" "unprognostic (4.74e-2)" "unprognostic (1.09e-1)" "unprognostic (9.55e-2)" "unprognostic (8.93e-3)" "unprognostic (1.79e-2)" "unprognostic (8.84e-2)" "unprognostic (7.86e-2)" "unprognostic (2.93e-2)" "unprognostic (1.88e-1)" "unprognostic (2.68e-4)" 17.1 13.3 17.3 10.2 18.5 10.5 15.3 19.4 19.2 16.6 9.0 22.5 15.3 15.8 6.4 14.9 12.9 7.4 15.0 18.4 17.1 17.0 10.1 11.9 9.3 19.3 18.2 14.8 12.7 10.7 9.4 7.3 16.1 12.9 8.8 5.8 12.3 10.9 25.7 17.5 16.8 8.9 16.1 10.8 16.4 5.3 17.8 9.4 10.6 15.5 7.4 18.0 14.9 18.5 31.1 22.3 14.7 14.2 17.3 12.4 7.9 10.0 13.6 23.3 21.3 17.6 23.7 30.7 16.7 17.4 29.3 16.8 16.8 15.2 9.8 47.0 14.0 15.8 18.2 30.2 18.3 10.7 24.5 10.6 22.2 24.7 14.5 13.0 14.1 22.6 27.0 19.6 12.5 18.8 29.2 36.8 15.5 12.0 21.9 23.7 8.4 34.0 17.6 6.7 25.6 19.2 25.3 23.0 23.2 9.7 23.4 18.6 27.5 23.5 22.9 24.1 14.7 20.9 38.3 30.3 23.2 14.5 8.4 9.2 13.6 13.6 7.6 16.2 6.2 8.9 7.8 6.8 9.4 8.7 5.6 5.1 2.1 4.3 23.6 6.4 8.3 7.3 17.3 18.5 19.4 19.2 18.4 17.1 19.3 18.2 16.1 16.1 17.8 18.5 0.3 0.0 3.3 0.0 0.8 1.0 0.1 0.4 4.0 0.0 0.5 0.3 0.4 0.0 0.2 0.0 0.0 0.4 0.1 5.6 0.0 4.8 0.0 0.1 0.2 0.9 7.8 1.3 0.0 3.1 0.6 0.4 1.1 0.1 8.2 0.4 0.7 0.1 1.0 0.0 0.0 3.3 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 7.9 0.2 0.0 0.0 0.0 3.9 8.0 0.4 1.1 0.0 6.5 0.6 0.7 0.4 0.0 0.7 1.0 0.0 0.0 1.5 0.4 0.4 1.1 0.2 5.6 0.1 SNX32 "FLJ30934, SNX6B" ENSG00000172803 "Sorting nexin 32" Q86XE0 11 65833834-65856896 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 12 "brain: 37.8;choroid plexus: 15.0" "Cell type enhanced" "Detected in some" "Astrocytes: 25.5;Early spermatids: 11.3;Excitatory neurons: 48.4;Inhibitory neurons: 34.2;Late spermatids: 12.3;Oligodendrocyte precursor cells: 12.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 4.5;HSkMC: 5.8;REH: 1.9;SH-SY5Y: 2.3;U-266/70: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041775 Uncertain Uncertain "Cell Junctions,Focal adhesion sites" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Cell Junctions, Focal adhesion sites" "HPA041775: AB_10797268" "unprognostic (6.74e-4)" "unprognostic (1.06e-1)" "unprognostic (1.67e-2)" "unprognostic (4.50e-5)" "unprognostic (1.00e-1)" "unprognostic (9.28e-2)" "unprognostic (7.30e-2)" "unprognostic (9.17e-3)" "unprognostic (2.70e-1)" "unprognostic (2.87e-1)" "unprognostic (5.08e-2)" "unprognostic (1.52e-1)" "unprognostic (3.64e-4)" "unprognostic (2.14e-1)" "unprognostic (1.14e-1)" "unprognostic (9.80e-2)" "unprognostic (5.36e-2)" 0.3 0.1 22.8 0.1 24.0 0.3 0.3 17.1 37.8 0.6 15.0 1.0 1.0 0.7 0.2 0.1 0.7 0.8 0.2 23.7 17.8 0.2 0.0 0.1 0.1 18.1 18.2 0.7 0.1 0.2 0.4 0.0 18.3 0.2 0.4 1.1 0.0 0.1 0.0 0.4 0.5 0.5 16.9 0.2 0.2 2.1 18.7 0.4 0.1 0.2 0.2 0.4 0.2 23.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.5 0.0 0.5 5.8 0.1 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.3 0.0 0.4 0.2 0.1 0.0 0.0 1.9 0.0 1.8 0.0 0.0 0.0 2.3 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 7.0 1.2 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.3 0.1 0.7 0.0 0.3 0.2 0.3 0.2 0.3 0.1 0.0 0.0 0.0 0.1 0.3 0.0 22.8 24.0 17.1 37.8 23.7 17.8 18.1 18.2 18.3 16.9 18.7 23.1 0.3 0.0 0.6 25.5 0.6 0.4 0.3 0.0 1.2 2.4 0.7 1.0 0.8 0.0 0.6 0.0 0.0 0.1 0.1 0.6 0.0 0.1 11.3 0.3 3.6 0.6 0.0 0.8 48.4 0.0 0.4 0.9 1.1 0.5 3.8 2.8 0.4 0.0 0.3 0.0 34.2 0.8 0.0 0.3 0.3 12.3 0.3 0.2 1.8 3.7 0.0 0.9 1.0 12.1 10.2 0.2 0.5 1.2 0.5 0.2 3.9 0.4 0.7 0.6 0.0 1.0 0.8 6.1 1.7 0.5 0.4 0.0 0.7 1.3 1.7 0.1 SNX7 ENSG00000162627 "Sorting nexin 7" Q9UNH6 1 98661701-98760500 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037419 Enhanced Approved "Vesicles,Cell Junctions" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" Vesicles "Cell Junctions" "HPA037419: AB_10671754" "unprognostic (3.19e-1)" "unprognostic (2.18e-1)" "prognostic favorable (5.10e-5)" "unprognostic (2.84e-2)" "unprognostic (1.14e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (9.59e-7)" "unprognostic (1.53e-2)" "unprognostic (2.64e-1)" "unprognostic (1.41e-2)" "unprognostic (1.19e-3)" "unprognostic (1.88e-1)" "unprognostic (7.95e-3)" "unprognostic (1.68e-1)" "unprognostic (1.45e-1)" "unprognostic (8.65e-2)" "unprognostic (1.77e-1)" 19.5 13.8 10.2 7.5 9.5 0.1 17.1 8.6 9.9 20.6 7.5 30.1 23.5 19.4 12.6 16.6 15.6 16.2 22.1 10.1 13.6 24.9 12.8 11.3 3.4 11.6 12.7 11.3 13.7 15.1 8.4 16.8 10.7 14.3 29.9 3.2 14.1 16.4 5.4 11.0 22.9 25.8 9.8 5.4 16.9 15.7 16.4 3.6 12.2 10.9 4.7 20.3 14.3 10.8 50.4 26.7 15.8 21.6 54.9 86.3 8.9 31.3 56.6 45.9 59.2 15.6 18.4 0.0 39.7 77.1 37.7 14.2 16.8 44.4 45.5 0.2 32.3 0.0 41.2 27.1 32.4 0.0 0.0 43.5 46.8 37.8 16.5 51.7 64.9 0.7 0.0 0.1 73.3 10.3 0.4 0.0 15.2 20.0 38.0 0.0 35.4 0.1 45.3 39.8 7.8 93.5 41.6 39.0 23.7 26.2 0.0 1.8 44.9 44.7 24.8 35.0 64.2 0.0 0.1 0.1 63.3 0.0 22.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.2 9.5 8.6 9.9 10.1 13.6 11.6 12.7 10.7 9.8 16.4 10.8 14.1 19.2 6.7 23.2 0.5 14.7 44.7 60.0 9.6 0.7 16.3 23.0 49.1 27.1 22.0 23.9 0.0 34.1 0.1 37.4 37.2 47.0 19.3 29.4 33.0 17.8 21.0 0.0 18.3 80.7 33.8 37.9 20.9 19.6 1.3 22.4 17.9 12.0 12.9 3.3 25.7 26.6 48.8 2.1 13.7 23.9 34.2 5.0 35.6 12.2 37.2 12.8 0.0 58.8 8.2 56.8 25.7 52.6 0.1 28.5 34.1 69.0 27.2 0.8 32.9 23.1 36.2 15.5 10.5 27.1 16.3 14.1 1.6 30.2 49.1 57.3 SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 251.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 146.6;GAMG: 145.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA031410: AB_10603339, HPA057203: AB_2683368" "unprognostic (1.63e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (1.39e-1)" "unprognostic (8.09e-2)" "unprognostic (8.09e-2)" "unprognostic (1.40e-2)" "unprognostic (4.06e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (7.93e-2)" "unprognostic (4.99e-3)" "unprognostic (4.45e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.95e-4)" "unprognostic (2.14e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" 57.9 25.2 19.2 25.7 20.6 14.3 41.4 21.2 20.9 38.8 20.6 34.2 33.2 41.8 20.8 57.8 26.2 46.9 33.2 18.8 19.9 26.2 39.0 21.0 24.2 22.2 21.1 28.0 28.5 37.7 13.4 48.5 21.8 31.0 29.5 2.7 35.1 41.7 24.4 30.4 35.6 41.2 20.9 18.4 37.5 11.0 20.7 13.9 29.8 34.2 21.7 49.8 33.7 23.0 26.0 19.1 18.9 22.1 96.6 78.6 37.7 46.3 146.6 36.4 48.9 16.6 27.6 0.0 25.0 85.6 145.8 18.7 22.7 36.3 21.1 23.9 23.4 17.7 25.7 23.9 48.6 7.6 31.6 51.1 33.9 37.8 37.1 63.9 49.8 23.3 80.9 0.0 15.8 17.2 0.0 15.6 14.4 18.7 21.3 0.0 17.9 32.7 59.7 15.9 11.8 20.9 34.1 16.4 90.5 16.2 6.8 20.0 41.7 41.3 16.6 128.8 30.4 0.0 0.0 0.0 84.8 6.4 25.4 0.0 0.7 0.1 0.4 2.1 1.5 3.2 0.7 0.6 1.4 2.4 5.3 1.2 0.0 0.1 6.8 10.0 2.2 0.6 19.2 20.6 21.2 20.9 18.8 19.9 22.2 21.1 21.8 20.9 20.7 23.0 71.5 0.0 1.1 40.5 102.6 43.3 109.7 17.3 30.1 15.6 28.7 18.4 28.4 28.6 19.0 9.2 0.0 40.6 37.6 97.7 21.5 57.5 73.4 112.8 53.0 57.9 15.7 17.7 105.4 55.9 41.1 83.0 70.3 251.1 12.0 16.4 37.1 34.3 41.6 3.3 90.4 43.0 8.2 59.0 74.2 26.8 44.7 84.3 21.4 48.7 39.5 11.1 7.2 100.5 161.2 107.0 108.9 46.6 14.9 127.5 52.5 46.2 14.3 1.8 39.5 43.6 49.6 21.9 15.4 22.9 29.8 109.9 48.8 9.1 29.7 137.0 SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 501.5" "Cell type enhanced" "Detected in many" "Adipocytes: 989.2;Endothelial cells: 635.9;Fibroblasts: 394.4;Langerhans cells: 381.5;Skeletal myocytes: 485.9;Smooth muscle cells: 381.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 6 "granulocytes: 9.5;T-cells: 3.1" "Cell line enhanced" "Detected in many" "HDLM-2: 154.2;HSkMC: 73.3;U-266/70: 76.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 9.8" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB012220: AB_443287, HPA068569: AB_2686008" "prognostic favorable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "unprognostic (4.41e-3)" "unprognostic (2.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (9.61e-3)" "unprognostic (1.84e-1)" "unprognostic (2.00e-2)" "prognostic unfavorable (9.34e-9)" "unprognostic (1.08e-2)" "unprognostic (8.80e-2)" "unprognostic (7.59e-3)" "unprognostic (8.40e-2)" 501.5 50.3 19.1 99.0 20.2 126.4 114.1 18.8 27.5 35.1 21.7 119.0 19.4 53.4 1.9 72.7 306.5 190.4 76.8 16.8 21.2 72.1 84.2 234.8 46.9 43.1 22.1 55.5 46.2 23.6 55.7 77.5 24.6 61.8 27.2 4.2 36.3 17.1 26.1 55.3 64.2 125.2 23.7 52.0 123.9 5.9 32.2 115.9 54.1 37.1 11.8 187.9 31.6 19.6 6.4 10.2 7.3 3.8 2.8 44.3 19.1 31.4 28.3 32.1 13.6 6.6 4.4 0.2 6.7 7.5 20.4 2.0 1.5 3.1 12.7 154.2 0.9 5.8 24.1 1.4 14.5 0.1 2.7 73.3 2.6 24.9 9.3 19.4 14.0 0.5 17.4 58.2 15.1 3.3 3.3 1.0 5.2 1.2 12.8 0.2 36.9 1.1 51.4 6.3 0.3 4.6 9.5 2.5 1.3 26.8 2.9 1.4 8.4 62.7 17.6 22.2 18.4 76.0 46.9 0.1 51.6 0.8 4.1 0.0 1.0 0.2 0.8 0.1 1.9 0.0 2.1 0.9 1.1 0.0 3.1 0.6 9.5 0.3 0.0 1.0 1.3 0.5 19.1 20.2 18.8 27.5 16.8 21.2 43.1 22.1 24.6 23.7 32.2 19.6 989.2 48.1 125.6 0.7 64.7 164.3 120.7 75.0 125.2 1.0 176.3 136.4 23.1 18.6 51.7 38.6 2.1 14.9 42.1 20.5 5.9 44.4 0.8 106.7 207.6 635.9 33.0 11.6 0.0 38.6 46.0 394.4 125.4 166.8 36.0 5.8 307.3 20.2 94.6 0.0 0.1 25.0 30.5 78.4 381.5 1.7 78.3 231.0 85.4 1.0 33.6 7.7 1.0 0.0 1.0 43.0 28.1 2.2 115.5 72.0 24.3 11.5 38.1 2.7 13.1 485.9 381.7 0.4 1.0 36.3 133.0 62.1 88.7 5.3 41.0 90.5 SOCS5 "CIS6, Cish5, CISH6, KIAA0671, SOCS-5" ENSG00000171150 "Suppressor of cytokine signaling 5" O75159 2 46698952-46780245 "Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ hTERT+: 121.0;fHDF/TERT166: 121.9;U-138 MG: 80.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020884, CAB025510" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 65: Plasmacytoid DCs - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "CAB025510: , HPA020884: AB_1857356" "unprognostic (1.69e-1)" "unprognostic (1.98e-2)" "unprognostic (5.71e-2)" "unprognostic (1.64e-2)" "unprognostic (2.20e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (7.28e-4)" "unprognostic (4.52e-2)" "unprognostic (9.13e-2)" "prognostic unfavorable (7.53e-4)" "unprognostic (2.10e-3)" "unprognostic (3.01e-1)" "unprognostic (1.47e-3)" "unprognostic (8.29e-2)" "unprognostic (1.71e-1)" "unprognostic (1.17e-1)" "unprognostic (1.29e-1)" 12.0 10.2 7.6 6.3 7.7 7.7 13.0 15.9 9.6 13.0 7.5 9.7 5.2 14.1 9.1 8.5 9.3 11.3 11.3 8.1 7.6 9.2 6.7 8.7 6.7 8.3 8.3 23.2 6.2 14.2 5.6 7.3 8.5 9.9 6.6 12.7 8.7 12.4 9.0 7.5 6.7 13.9 8.5 9.0 6.6 10.3 8.2 7.6 9.9 16.0 6.7 9.3 8.5 8.6 14.5 10.8 9.3 13.8 29.9 42.3 11.4 66.5 121.0 31.5 18.6 10.3 6.9 7.5 12.7 121.9 9.7 7.1 9.9 10.8 41.2 7.3 9.4 11.8 10.0 13.2 18.4 6.9 12.7 33.9 15.8 26.7 10.7 35.8 11.0 3.0 10.2 8.1 21.5 5.3 5.9 12.0 10.4 15.1 8.7 7.8 15.9 9.5 13.2 11.1 7.3 19.8 16.4 10.7 13.0 8.9 4.4 10.3 12.8 80.0 17.7 26.9 13.2 9.7 6.4 6.5 36.9 13.7 25.5 0.5 0.4 2.5 0.9 0.4 1.1 1.8 0.5 0.6 0.5 3.0 1.1 1.5 0.4 1.0 1.7 0.5 1.0 0.7 7.6 7.7 15.9 9.6 8.1 7.6 8.3 8.3 8.5 8.5 8.2 8.6 17.2 3.2 6.1 18.9 11.3 16.6 7.2 8.3 16.5 12.8 15.1 12.2 14.2 18.6 8.0 3.7 22.9 3.7 6.2 11.0 5.9 7.3 12.3 9.9 29.2 24.3 10.8 6.1 43.4 6.8 2.5 18.8 10.2 12.0 17.1 17.4 17.2 7.9 4.5 18.5 51.5 7.1 2.0 8.4 15.2 8.1 17.4 7.7 7.2 18.7 8.4 9.7 6.2 38.2 25.4 6.8 8.8 17.0 7.0 11.0 5.1 7.3 5.3 5.5 13.1 13.8 20.1 13.3 18.8 9.9 14.5 2.7 7.0 7.3 5.6 7.8 SOD1 "ALS, ALS1, IPOA" ENSG00000142168 "Superoxide dismutase 1" P00441 21 31659666-31668931 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Antioxidant, Oxidoreductase" "Amyotrophic lateral sclerosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 1645.6" "Cell type enhanced" "Detected in all" "Hepatocytes: 3357.9;Proximal tubular cells: 3285.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001401, CAB008670" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 44900000 50000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 16: U-266 - Nucleosome" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Nucleoplasm, Plasma membrane, Cytosol" "CAB008670: AB_1623312, HPA001401: AB_1080132" "unprognostic (1.73e-1)" "unprognostic (1.18e-2)" "unprognostic (4.43e-1)" "unprognostic (6.19e-2)" "unprognostic (1.39e-1)" "unprognostic (9.59e-3)" "unprognostic (8.34e-2)" "unprognostic (2.30e-1)" "unprognostic (3.47e-1)" "unprognostic (5.28e-2)" "unprognostic (9.33e-2)" "unprognostic (1.96e-1)" "unprognostic (1.03e-2)" "unprognostic (1.66e-1)" "unprognostic (1.74e-2)" "unprognostic (1.57e-1)" "unprognostic (3.26e-2)" 257.6 597.1 558.0 118.4 577.4 166.4 233.5 605.2 805.1 206.6 586.6 251.0 360.3 179.5 228.4 221.1 197.1 206.0 477.3 575.1 619.9 483.2 1645.6 153.9 169.6 619.8 604.6 302.1 117.1 210.6 236.7 155.8 653.1 203.9 180.5 248.6 160.5 204.2 428.0 152.1 266.7 136.6 588.1 147.5 210.4 132.1 585.8 165.7 197.4 355.9 151.7 232.1 220.6 634.7 526.8 451.4 309.2 312.8 407.3 282.1 257.8 430.2 258.0 291.3 217.4 593.6 326.0 628.2 441.2 405.8 517.7 186.1 453.3 320.6 239.9 463.3 540.0 1008.2 579.5 866.3 267.4 451.7 363.1 294.8 240.6 406.5 225.2 327.9 331.2 469.0 704.4 773.2 357.4 860.0 489.0 454.5 466.1 830.0 475.4 413.0 622.0 981.4 579.4 320.5 335.9 281.4 805.1 419.4 438.3 279.2 484.3 393.4 387.4 222.9 489.2 304.7 322.0 583.4 1374.2 741.8 455.7 654.3 301.9 204.2 159.7 194.0 313.4 234.0 365.3 427.1 509.2 402.4 212.8 310.1 521.8 412.1 37.8 241.4 465.4 240.6 746.0 474.5 558.0 577.4 605.2 805.1 575.1 619.9 619.8 604.6 653.1 588.1 585.8 634.7 319.8 294.9 175.1 38.2 248.1 491.4 672.7 479.2 319.8 226.6 264.1 352.9 721.0 527.6 294.7 391.8 47.9 703.4 250.2 703.5 1631.7 426.3 277.0 410.7 241.2 261.0 288.4 898.8 39.7 807.3 574.9 365.8 198.8 216.3 220.0 278.9 318.1 3357.9 363.3 282.7 45.5 402.7 366.2 220.0 318.5 952.2 521.9 224.2 419.8 29.0 313.1 598.5 239.0 28.6 68.7 322.8 600.9 528.1 178.2 567.0 1158.3 3285.9 638.3 216.5 440.4 313.6 404.5 211.7 506.3 379.9 349.8 725.9 423.1 470.3 593.6 497.7 SORBS1 "CAP, FLJ12406, KIAA1296, ponsin, SH3D5, sh3p12" ENSG00000095637 "Sorbin and SH3 domain containing 1" Q9BX66 10 95311771-95561414 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 800.2;Cardiomyocytes: 612.3;Excitatory neurons: 401.1;Inhibitory neurons: 295.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "basophil: 6.1" "Lineage enriched" "Detected in single" 10 "granulocytes: 6.1" "Cell line enhanced" "Detected in many" "CACO-2: 28.0;Hep G2: 19.5;HMC-1: 48.3;SK-MEL-30: 45.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027559, CAB032850, HPA043084" Enhanced Supported "Plasma membrane,Focal adhesion sites,Centrosome" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 3: HMC-1 - Innate immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Focal adhesion sites" "Plasma membrane, Centrosome" "CAB032850: AB_2286335, HPA027559: AB_10600812, HPA043084: AB_2678307" "prognostic favorable (2.84e-4)" "unprognostic (3.53e-1)" "unprognostic (1.89e-1)" "unprognostic (7.85e-2)" "unprognostic (3.43e-1)" "unprognostic (1.41e-1)" "unprognostic (2.98e-2)" "unprognostic (5.30e-2)" "unprognostic (1.95e-2)" "unprognostic (1.65e-2)" "unprognostic (3.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.40e-2)" "unprognostic (3.13e-2)" "unprognostic (1.80e-1)" "unprognostic (2.55e-2)" "unprognostic (5.01e-3)" 370.8 21.6 128.5 53.3 153.3 4.7 78.3 101.7 144.1 46.0 42.6 312.8 25.6 169.4 32.1 155.5 99.2 81.3 351.6 127.0 165.4 17.6 49.3 34.4 3.1 164.0 161.5 19.0 22.0 26.4 11.5 30.3 126.7 140.6 67.0 39.0 24.5 217.4 190.5 24.5 62.7 151.0 138.9 8.1 143.1 14.4 127.0 3.7 14.8 155.9 1.5 235.3 47.1 139.9 1.6 1.2 12.4 3.1 4.2 0.2 2.4 0.4 0.1 0.4 0.1 28.0 10.9 0.0 2.2 0.2 4.2 0.6 2.4 0.6 0.4 3.2 4.5 7.2 0.4 19.5 1.5 0.0 48.3 0.9 0.4 0.5 0.3 0.2 4.9 1.9 11.7 2.3 1.3 0.8 0.1 0.8 5.7 6.2 2.6 1.0 4.0 0.4 15.1 18.3 4.9 3.7 1.8 0.6 45.2 8.9 2.1 0.4 0.3 0.1 4.0 0.1 2.4 1.8 0.5 0.2 4.8 0.5 11.7 6.1 0.1 1.2 0.4 0.6 0.5 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.4 0.1 0.0 0.3 0.1 128.5 153.3 101.7 144.1 127.0 165.4 164.0 161.5 126.7 138.9 127.0 139.9 42.2 22.4 20.9 800.2 0.8 11.6 8.7 0.0 5.2 7.5 6.5 19.3 612.3 12.8 1.3 1.8 2.1 20.2 1.0 4.0 3.9 7.2 70.4 1.4 15.8 25.7 6.0 16.0 401.1 3.1 2.4 21.4 8.6 1.6 16.4 8.2 30.4 50.5 3.1 6.7 295.1 10.9 0.0 3.8 12.0 48.6 7.5 1.1 14.2 163.9 0.7 22.1 1.0 155.3 22.6 2.3 2.8 76.8 1.1 4.7 1.2 6.1 0.1 5.5 0.0 11.8 51.6 3.4 3.7 1.9 12.5 29.6 1.6 0.1 5.1 5.9 SORCS1 ENSG00000108018 "Sortilin related VPS10 domain containing receptor 1" Q8WY21 10 106573663-107164534 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;thyroid gland: 11.0" "Group enriched" "Detected in some" 7 "Excitatory neurons: 522.2;Inhibitory neurons: 179.7;Oligodendrocyte precursor cells: 381.5" "Cancer enhanced" "Detected in some" "melanoma: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "RH-30: 80.8;SH-SY5Y: 104.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011948 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA011948: AB_1857366" "unprognostic (5.86e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-2)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (1.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.52e-2)" "unprognostic (5.58e-2)" "unprognostic (6.82e-3)" "unprognostic (5.81e-2)" "unprognostic (6.48e-4)" "unprognostic (2.51e-2)" "unprognostic (8.89e-3)" "unprognostic (2.22e-1)" "unprognostic (2.69e-4)" 0.6 3.1 3.0 1.9 6.2 0.0 1.3 0.0 10.3 2.5 0.0 9.4 0.7 1.1 0.3 0.9 1.6 1.1 3.1 5.4 5.8 4.7 0.1 0.1 1.0 0.6 4.5 0.7 1.6 0.0 0.9 0.0 2.7 2.2 1.9 9.6 1.1 2.5 0.3 1.5 3.6 1.4 0.5 0.8 2.5 1.2 5.8 1.0 11.0 1.7 1.5 3.6 2.8 6.6 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 80.8 0.1 0.0 0.0 0.0 104.9 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 6.2 0.0 10.3 5.4 5.8 0.6 4.5 2.7 0.5 5.8 6.6 0.0 0.0 0.5 7.2 0.0 0.6 0.0 0.0 1.2 2.0 0.1 0.5 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 16.6 0.1 4.9 0.2 0.0 0.0 522.2 0.0 0.0 3.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 1.7 179.7 0.0 0.0 0.3 0.3 5.2 0.0 0.2 1.8 26.2 0.0 49.1 0.0 381.5 10.0 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 2.1 0.0 1.0 0.3 0.2 1.9 0.2 0.1 0.0 0.3 0.0 0.0 0.0 SORT1 "Gp95, NT3" ENSG00000134243 "Sortilin 1" Q99523 1 109309568-109397918 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Endocytosis, Osteogenesis, Transport" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 285.6" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 447.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 9.2;non-classical monocyte: 10.8" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006889, CAB011498" Enhanced Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 7170000 110000 "Cluster 51: Monocytes - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Golgi apparatus, Cytosol" "Plasma membrane" "CAB011498: AB_2192606, HPA006889: AB_1080056" "unprognostic (2.10e-2)" "unprognostic (7.46e-2)" "prognostic favorable (7.74e-6)" "unprognostic (4.12e-1)" "unprognostic (9.41e-2)" "unprognostic (1.40e-1)" "prognostic unfavorable (1.23e-4)" "unprognostic (3.34e-3)" "unprognostic (4.27e-2)" "unprognostic (9.44e-2)" "unprognostic (2.42e-2)" "unprognostic (1.28e-2)" "unprognostic (1.23e-3)" "unprognostic (1.45e-2)" "unprognostic (2.15e-1)" "unprognostic (3.95e-1)" "unprognostic (4.46e-3)" 48.2 11.3 71.0 12.0 168.3 21.4 25.1 124.3 114.2 17.7 21.5 29.5 22.1 24.7 139.8 41.5 27.5 17.8 64.7 131.8 90.0 38.7 6.5 37.4 2.8 151.9 133.8 6.1 17.5 46.5 11.3 44.8 153.1 18.3 26.9 40.0 25.2 44.0 85.0 19.0 21.9 27.8 102.8 10.2 18.2 43.5 118.0 6.4 42.7 71.8 10.3 16.9 18.0 285.6 38.8 15.3 37.5 45.8 107.0 21.2 107.3 28.2 44.9 27.2 29.0 39.8 14.0 0.3 35.2 11.9 19.9 9.4 44.7 22.3 38.9 1.1 21.2 10.7 23.5 43.1 41.8 0.2 33.5 53.2 3.6 33.3 7.3 72.6 4.2 31.7 81.3 4.0 38.7 41.1 27.9 0.8 14.1 17.5 6.3 30.7 87.9 18.9 52.0 27.8 38.3 21.8 16.6 109.3 120.6 53.1 46.1 6.7 1.1 5.8 21.7 1.0 47.6 37.0 32.2 0.3 9.8 0.3 24.3 0.0 7.1 2.5 0.0 9.2 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 1.8 0.4 10.8 1.6 0.0 2.0 71.0 168.3 124.3 114.2 131.8 90.0 151.9 133.8 153.1 102.8 118.0 285.6 10.6 38.5 47.9 54.5 1.9 1.3 4.7 6.7 1.2 14.9 27.5 14.2 98.9 27.1 20.3 75.4 35.5 30.6 3.2 70.2 5.9 23.9 65.1 33.2 5.2 15.9 16.8 4.0 87.9 23.7 30.2 9.8 16.8 34.9 7.6 10.4 7.9 22.1 30.1 13.5 56.7 27.7 6.1 38.7 9.9 79.7 8.7 34.6 21.4 78.7 37.7 21.7 0.0 48.7 447.8 25.6 23.2 49.7 1.5 7.1 64.0 13.1 29.6 50.7 32.9 25.1 53.6 46.3 21.6 9.3 1.8 36.8 2.1 1.8 28.3 10.8 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284379-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.1;Inhibitory neurons: 273.7;Respiratory ciliated cells: 330.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA037542: AB_10672353" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.90e-4)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-1)" "unprognostic (1.17e-1)" 16.3 16.8 36.6 6.4 37.4 2.4 20.8 35.1 45.9 21.0 39.0 16.5 18.8 18.2 31.6 26.1 46.5 22.0 22.2 34.2 37.8 30.4 18.8 10.8 11.5 38.8 39.6 25.8 15.5 24.4 29.7 9.8 37.8 22.1 17.2 21.5 15.7 20.5 10.3 24.9 10.9 12.1 40.9 8.0 26.1 46.3 38.4 13.0 26.4 10.8 13.8 18.9 19.4 40.6 26.8 9.9 29.4 0.0 19.3 35.0 0.2 14.3 17.1 18.3 19.3 20.8 28.8 11.1 16.7 16.0 29.3 18.5 13.4 17.4 38.6 0.0 10.5 5.8 28.0 24.6 21.9 6.3 0.1 30.1 23.5 16.3 9.5 25.0 7.6 11.6 18.8 12.3 18.4 0.0 21.4 0.1 16.3 0.0 8.7 22.6 30.9 0.5 29.4 25.8 21.4 25.1 16.3 15.1 21.3 24.2 70.3 2.7 7.8 17.2 9.2 9.3 15.1 20.0 9.7 0.4 28.6 0.0 8.0 2.0 0.3 0.9 8.1 1.3 11.7 9.3 9.1 10.4 3.1 8.5 12.0 10.4 0.5 15.4 0.9 5.1 9.4 3.4 36.6 37.4 35.1 45.9 34.2 37.8 38.8 39.6 37.8 40.9 38.4 40.6 17.7 16.0 19.5 89.5 10.7 42.3 46.6 82.8 22.8 47.6 38.0 45.6 67.5 74.4 73.6 40.5 95.9 50.6 7.5 17.1 76.3 44.0 243.1 207.0 31.3 18.5 38.2 9.0 205.9 24.9 20.8 30.8 32.1 30.3 10.1 34.0 12.8 16.9 11.7 40.4 273.7 37.8 101.7 4.6 9.6 86.2 41.3 5.9 23.2 42.2 29.2 82.7 8.2 92.0 74.9 27.3 18.8 44.8 9.4 25.4 9.4 94.9 330.0 69.0 13.1 30.8 36.1 167.9 31.0 64.6 56.4 23.5 12.9 55.3 39.8 53.8 SPANXN4 "CT11.9, SPANX-N4" ENSG00000189326 "SPANX family member N4" Q5MJ08 X 143025918-143034702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 59 "testis: 25.9" "Group enriched" "Detected in some" 165 "Early spermatids: 97.7;Late spermatids: 298.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045730, HPA059094" Uncertain Approved "Nuclear membrane,Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "Nuclear membrane" "HPA045730: AB_10961036, HPA059094: " 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 298.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPART "KIAA0610, SPG20, TAHCCP1" ENSG00000133104 Spartin Q8N0X7 13 36301638-36370180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.0;Proximal tubular cells: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 172.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 172.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039053, HPA039054" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol "Plasma membrane" "HPA039053: AB_10672769, HPA039054: AB_2676323" "unprognostic (3.73e-2)" "unprognostic (9.39e-2)" "unprognostic (3.06e-2)" "unprognostic (4.60e-2)" "unprognostic (2.21e-2)" "unprognostic (1.10e-2)" "unprognostic (9.18e-3)" "unprognostic (9.58e-2)" "unprognostic (3.36e-2)" "unprognostic (2.22e-1)" "unprognostic (7.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.54e-1)" "unprognostic (9.26e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-2)" "unprognostic (5.79e-2)" 42.3 48.4 36.9 18.0 42.8 23.6 32.5 43.4 50.6 49.2 42.3 37.8 12.7 42.4 67.1 24.5 44.5 37.4 25.7 35.3 39.4 48.4 19.9 27.0 15.7 42.4 40.5 63.6 14.6 29.5 29.6 39.8 42.1 34.7 13.3 43.3 17.3 36.4 33.5 18.4 15.4 52.8 41.2 30.7 21.1 27.6 38.3 16.7 35.6 33.7 11.2 35.5 29.9 51.0 0.1 22.4 59.5 0.0 127.9 106.6 42.4 54.1 81.3 53.7 52.8 0.1 0.0 0.0 32.9 65.9 98.2 31.2 81.4 38.0 57.5 4.4 46.9 69.4 28.3 14.6 128.0 72.8 134.3 106.2 59.5 44.4 61.9 131.7 79.6 18.7 30.6 11.9 97.5 5.2 21.7 120.8 30.0 0.0 7.8 0.0 99.4 2.5 62.5 28.2 6.2 14.5 46.3 18.3 58.9 85.3 10.5 84.7 66.8 40.0 20.1 55.9 32.2 14.2 0.2 0.1 44.6 61.8 71.0 172.7 22.1 30.1 13.5 21.7 13.1 10.1 18.6 5.4 15.7 9.7 24.5 13.1 35.0 14.2 23.8 19.3 4.8 18.1 36.9 42.8 43.4 50.6 35.3 39.4 42.4 40.5 42.1 41.2 38.3 51.0 43.5 35.3 51.5 0.0 6.1 0.0 0.0 0.0 0.0 0.0 30.8 30.1 0.0 0.0 40.2 27.6 0.0 52.7 18.6 0.0 66.5 26.2 0.0 59.4 62.6 15.9 0.0 0.0 0.0 15.0 59.7 39.8 0.0 38.1 58.0 75.0 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 16.8 0.0 0.0 3.5 0.0 0.0 90.4 65.6 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 64.3 10.8 59.2 0.0 0.0 SPATA12 ENSG00000186451 "Spermatogenesis associated 12" Q7Z6I5 3 57060664-57075432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 20.5" "Group enriched" "Detected in some" 145 "Early spermatids: 464.2;Late spermatids: 1195.5" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.9;RH-30: 1.1" "HPA043323, HPA075578" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" No No "Cluster 78: Testis - Spermatogenesis" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA043323: AB_10796792, HPA075578: " "unprognostic (2.31e-1)" "unprognostic (2.18e-4)" "unprognostic (3.47e-4)" "unprognostic (2.21e-2)" "unprognostic (2.66e-1)" "unprognostic (8.79e-3)" "unprognostic (1.69e-3)" "unprognostic (3.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.29e-1)" "unprognostic (6.80e-2)" "unprognostic (1.76e-2)" "unprognostic (4.71e-3)" "unprognostic (7.29e-2)" "unprognostic (1.62e-2)" "unprognostic (1.14e-1)" "unprognostic (2.44e-3)" 0.0 0.3 0.4 0.0 0.3 0.0 0.0 0.2 0.2 0.1 2.1 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.6 0.0 0.0 0.3 0.2 2.0 0.8 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.3 20.5 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.1 0.1 0.0 1.9 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.4 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.4 0.5 0.0 1.1 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.3 0.0 0.7 0.1 0.1 0.0 0.1 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.2 0.2 0.2 0.6 2.0 0.8 0.7 0.5 0.4 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.4 464.2 1.0 0.1 0.6 0.0 0.0 0.1 1.0 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 3.1 0.0 0.1 0.0 0.0 1.3 0.0 1195.5 5.0 0.5 0.0 1.0 0.0 0.0 0.0 1.0 0.7 1.4 0.1 5.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 2.8 0.3 0.0 0.0 0.3 0.0 0.2 0.5 SPATC1L C21orf56 ENSG00000160284 "Spermatogenesis and centriole associated 1 like" Q9H0A9 21 46161148-46184476 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 48.9" "Group enriched" "Detected in many" 5 "Early spermatids: 208.9;Late spermatids: 472.3" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 4 "amygdala: 4.2;basal ganglia: 3.7;cerebral cortex: 4.8;hippocampal formation: 2.9" "Immune cell enhanced" "Detected in many" "eosinophil: 36.1" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 37.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018979, HPA019165, HPA029394" Approved Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 25: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane, Cytosol" "HPA018979: AB_1845696, HPA019165: AB_1845697, HPA029394: AB_10601148" "unprognostic (1.46e-2)" "unprognostic (3.88e-2)" "unprognostic (3.95e-2)" "unprognostic (4.86e-2)" "unprognostic (6.36e-2)" "unprognostic (1.71e-1)" "unprognostic (4.45e-3)" "unprognostic (2.16e-1)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "prognostic favorable (2.16e-4)" "unprognostic (5.56e-2)" "unprognostic (2.35e-3)" "unprognostic (1.07e-1)" "unprognostic (1.47e-1)" "unprognostic (1.91e-2)" "unprognostic (2.58e-1)" 7.6 23.4 4.2 1.0 3.7 1.3 8.5 0.0 4.8 11.4 0.0 9.7 1.3 9.8 0.6 7.7 6.8 1.4 11.5 2.9 0.6 7.3 1.3 5.9 1.6 0.4 0.1 13.9 11.3 1.6 14.2 1.1 0.1 32.5 0.7 0.3 6.7 2.5 5.6 10.5 6.9 0.8 0.0 8.4 8.3 48.9 0.9 1.0 6.3 0.8 1.0 9.8 11.7 0.1 2.9 0.0 3.6 6.7 2.0 4.7 1.9 4.1 2.2 2.2 1.7 0.0 1.8 9.0 8.0 5.0 2.6 0.5 0.0 3.2 0.6 8.3 6.6 21.6 1.3 5.0 0.1 0.0 8.5 5.0 1.5 0.0 0.0 4.2 7.2 10.1 37.8 13.2 3.1 5.7 7.0 2.5 15.0 4.0 18.0 15.4 4.9 10.0 3.4 0.8 1.1 6.9 3.2 1.7 8.6 2.5 5.6 8.3 0.4 6.5 8.0 9.3 6.3 21.9 12.6 6.6 8.6 11.9 6.1 1.5 5.7 36.1 4.3 6.8 5.6 7.6 6.2 5.9 8.6 7.6 9.7 9.2 0.3 6.6 4.7 7.2 7.0 3.6 4.2 3.7 0.0 4.8 2.9 0.6 0.4 0.1 0.1 0.0 0.9 0.1 20.5 0.0 0.0 3.6 13.5 23.6 11.6 21.4 18.2 6.8 11.9 14.6 1.9 12.8 6.9 3.7 0.0 3.4 10.1 7.7 15.6 16.8 208.9 6.3 14.6 15.4 60.4 12.8 2.6 20.5 17.7 18.1 13.7 8.8 0.0 18.8 14.6 0.6 13.7 3.3 2.0 16.4 8.2 8.8 24.4 472.3 32.3 9.9 28.4 1.0 5.9 5.8 6.2 3.0 3.1 17.8 6.6 31.6 28.0 24.1 6.8 13.4 2.8 3.1 19.7 12.0 14.0 17.8 14.7 17.0 40.1 3.1 11.7 4.0 18.3 8.1 SPG11 "ALS5, FLJ21439, KIAA1840" ENSG00000104133 "SPG11 vesicle trafficking associated, spatacsin" Q96JI7 15 44562696-44663678 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Amyotrophic lateral sclerosis, Charcot-Marie-Tooth disease, Hereditary spastic paraplegia, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 121.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040412, HPA040947" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoli "HPA040412: AB_10795418, HPA040947: AB_10796232" "unprognostic (1.10e-1)" "unprognostic (1.74e-1)" "unprognostic (2.39e-1)" "unprognostic (1.98e-3)" "unprognostic (1.99e-1)" "unprognostic (9.31e-2)" "unprognostic (2.91e-1)" "unprognostic (2.32e-1)" "unprognostic (6.71e-2)" "unprognostic (2.26e-3)" "unprognostic (2.58e-2)" "unprognostic (9.19e-2)" "prognostic favorable (6.28e-5)" "unprognostic (8.73e-2)" "unprognostic (2.48e-1)" "unprognostic (3.72e-1)" "unprognostic (6.06e-2)" 21.1 27.1 18.4 18.2 25.7 27.4 21.6 24.4 21.3 21.5 23.9 25.6 17.1 17.9 25.3 25.6 20.2 16.1 25.5 17.5 22.2 25.0 29.8 24.8 28.4 23.8 22.1 21.4 28.6 26.7 21.3 14.9 23.9 25.3 19.9 30.5 24.7 15.0 22.9 30.4 30.1 12.7 19.1 43.0 26.0 25.5 24.6 23.7 30.9 14.3 18.6 23.8 22.6 33.4 13.2 8.8 21.9 21.6 33.7 33.0 15.8 13.4 17.4 13.0 16.6 10.8 12.5 9.7 16.5 18.2 22.5 29.0 15.1 20.8 12.5 29.3 9.0 22.1 21.1 16.4 23.7 22.2 19.2 25.3 23.3 10.7 30.5 20.4 18.6 16.6 28.8 24.2 18.6 11.5 10.1 19.7 11.5 40.3 11.6 12.9 18.5 10.6 28.0 33.6 14.2 16.8 14.6 23.3 13.1 18.0 22.0 30.2 19.9 17.1 8.5 21.4 16.5 23.8 22.6 19.2 17.6 28.8 17.9 5.7 7.7 11.8 6.5 9.2 6.9 10.0 5.4 4.9 6.2 11.3 4.3 5.3 11.6 6.2 12.4 6.3 6.1 3.7 18.4 25.7 24.4 21.3 17.5 22.2 23.8 22.1 23.9 19.1 24.6 33.4 21.0 44.8 22.2 56.2 40.4 9.3 15.6 18.8 14.2 25.1 19.0 12.6 20.1 18.6 31.3 27.6 47.9 16.5 30.1 29.3 5.9 21.3 28.2 31.7 23.2 17.6 20.0 22.3 62.9 16.9 10.1 19.3 37.2 33.6 27.3 31.9 21.8 23.5 20.1 16.8 68.1 31.2 26.4 43.3 23.5 33.2 17.7 40.4 14.2 74.9 88.1 14.0 50.4 68.3 121.4 17.7 24.0 13.9 21.4 19.3 30.8 14.9 53.6 21.7 6.6 24.8 16.3 51.7 31.6 20.1 11.1 9.3 29.5 24.4 27.3 22.2 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 328.8" "Group enriched" "Detected in some" 6 "Leydig cells: 39.7;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HeLa: 574.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" 0.3 1.9 0.7 0.1 1.2 0.0 0.0 0.9 1.0 0.2 0.0 1.1 0.0 0.2 328.8 0.1 0.4 0.2 0.5 0.4 0.8 0.6 0.0 0.3 0.1 1.3 0.8 0.5 0.2 0.0 0.5 0.0 1.4 1.7 0.0 1.5 0.2 31.3 0.4 0.5 0.0 0.1 0.7 0.0 1.6 1.3 1.1 0.1 0.3 0.0 0.0 1.5 0.1 2.8 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 574.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.0 0.3 30.0 0.2 0.3 0.0 22.5 0.0 0.0 0.2 1.9 0.0 0.6 1.1 0.1 0.4 0.1 0.6 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.9 1.0 0.4 0.8 1.3 0.8 1.4 0.7 1.1 2.8 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 0.0 0.1 39.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 2.8 0.0 26.7 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPINT1 "HAI, MANSC2" ENSG00000166145 "Serine peptidase inhibitor, Kunitz type 1" O43278 15 40844018-40858207 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 255.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 1254.0;Distal enterocytes: 477.6;Proximal enterocytes: 514.5;Syncytiotrophoblasts: 1673.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BEWO: 323.2;HaCaT: 377.6;hTCEpi: 264.0;RT4: 308.2;SK-BR-3: 558.8;T-47d: 267.7" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA006903, HPA031178" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" "Secreted to blood" NA NA 7400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" Nucleoplasm "HPA006903: AB_1079038, HPA031178: AB_2732463" "prognostic unfavorable (6.97e-4)" "unprognostic (1.00e-3)" "unprognostic (3.00e-3)" "unprognostic (5.03e-2)" "unprognostic (6.06e-2)" "unprognostic (3.19e-1)" "unprognostic (5.94e-2)" "unprognostic (6.04e-2)" "unprognostic (8.24e-3)" "unprognostic (1.46e-2)" "unprognostic (1.09e-3)" "unprognostic (1.01e-1)" "prognostic favorable (1.37e-7)" "unprognostic (5.37e-2)" "unprognostic (2.22e-1)" "unprognostic (6.45e-3)" "unprognostic (2.17e-2)" 2.8 0.7 0.9 16.4 1.5 1.4 34.7 5.0 1.3 42.8 6.4 108.7 159.9 13.2 78.9 255.5 33.6 38.0 1.3 0.9 2.0 79.9 3.5 47.6 6.4 2.8 3.2 2.4 69.2 132.9 31.4 144.9 2.2 52.3 89.2 0.4 162.7 31.4 0.6 148.9 138.2 4.3 1.7 6.9 88.3 1.8 3.2 9.9 34.7 0.4 45.5 57.1 90.1 2.3 124.8 1.0 0.0 0.9 0.1 0.0 323.2 2.3 3.0 4.0 2.4 195.3 202.4 0.3 141.2 0.4 3.6 377.6 30.8 181.9 2.4 1.0 10.6 5.6 3.3 10.8 2.2 21.9 93.9 0.3 264.0 3.9 16.5 3.4 14.7 12.1 2.7 1.1 0.2 96.5 0.9 16.6 37.4 207.6 17.7 12.6 0.0 24.9 179.3 308.2 79.8 3.9 9.3 558.8 15.7 56.9 267.7 16.1 0.0 0.2 2.0 1.2 0.5 1.2 24.5 0.8 0.8 16.3 1.1 0.0 19.7 14.3 0.4 15.9 0.8 8.4 3.0 1.4 32.4 6.0 1.1 0.3 25.9 5.5 18.1 4.0 0.5 7.6 0.9 1.5 5.0 1.3 0.9 2.0 2.8 3.2 2.2 1.7 3.2 2.3 0.8 57.7 14.7 0.0 7.6 76.0 96.7 220.0 55.8 0.1 96.2 63.5 0.5 105.8 207.3 134.3 0.0 1254.0 1.4 477.6 25.4 429.4 0.8 63.3 14.2 6.9 147.3 4.8 0.5 255.1 105.1 10.4 106.5 155.6 10.2 1.9 0.4 0.5 135.4 0.0 0.5 169.4 221.8 10.0 23.8 1.1 3.7 19.8 14.2 0.0 68.6 0.0 0.0 0.0 0.0 309.8 375.2 0.0 2.1 135.7 514.5 44.2 46.6 0.3 0.0 0.1 12.6 0.6 5.9 93.2 87.9 1673.8 6.6 0.1 182.7 222.3 SPINT2 "HAI-2, Kop" ENSG00000167642 "Serine peptidase inhibitor, Kunitz type 2" O43291 19 38244035-38292615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 1371.3;Syncytiotrophoblasts: 1413.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 852.5;CAPAN-2: 1219.1;OE19: 1500.4;RPTEC TERT1: 896.7;SK-BR-3: 789.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011101, CAB018969" Approved Uncertain "Plasma membrane,Intermediate filaments,Cytosol" No NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Intermediate filaments, Cytosol" "CAB018969: , HPA011101: AB_1079039" "unprognostic (5.13e-2)" "unprognostic (1.06e-3)" "unprognostic (1.40e-1)" "unprognostic (6.25e-2)" "unprognostic (1.13e-1)" "unprognostic (1.91e-2)" "unprognostic (2.23e-1)" "unprognostic (2.03e-2)" "unprognostic (3.51e-1)" "unprognostic (1.67e-2)" "unprognostic (2.89e-2)" "unprognostic (2.04e-1)" "prognostic favorable (3.41e-4)" "unprognostic (3.59e-1)" "unprognostic (1.32e-1)" "unprognostic (6.94e-2)" "unprognostic (2.68e-2)" 10.5 44.6 56.9 65.3 57.3 81.1 178.5 47.2 66.3 145.6 80.0 297.0 247.4 44.6 269.6 351.9 189.7 105.1 13.6 58.9 92.9 216.1 14.3 138.3 37.4 52.0 54.8 83.3 234.2 252.9 435.9 156.4 56.2 181.8 251.7 23.6 503.9 111.3 1.8 257.0 267.0 19.0 47.6 50.2 219.4 215.7 70.3 82.6 321.3 0.9 101.3 140.1 157.6 51.0 852.5 603.0 3.0 3.4 0.4 0.0 387.4 16.2 1.7 1.2 2.6 426.8 1219.1 6.7 65.8 4.6 1.2 274.6 42.7 587.0 1.4 7.9 51.7 159.4 15.3 0.9 0.9 1.5 0.8 0.1 662.5 0.7 278.6 71.5 2.0 144.2 4.0 0.4 1.0 652.8 25.6 2.8 60.4 1500.4 172.1 87.9 0.6 386.2 896.7 707.4 222.2 3.4 246.5 789.2 2.1 231.0 353.7 104.5 0.7 1.2 4.7 3.4 3.2 56.1 76.4 47.6 1.0 11.2 1.0 515.9 127.4 531.9 3.8 91.1 7.9 143.2 44.2 21.5 297.7 160.4 86.1 80.4 56.4 19.0 64.4 523.5 19.1 142.8 56.9 57.3 47.2 66.3 58.9 92.9 52.0 54.8 56.2 47.6 70.3 51.0 8.0 368.6 233.9 10.4 90.9 376.9 563.9 954.0 278.9 14.3 487.2 518.2 2.8 316.0 655.6 559.1 6.2 1371.3 79.5 1028.3 101.8 866.9 61.8 401.4 47.3 24.3 360.5 83.9 20.7 659.8 502.0 34.6 234.5 490.4 115.5 371.8 32.5 2.0 230.3 3.3 39.8 672.8 734.5 55.5 139.0 55.6 19.0 133.6 88.9 24.4 364.3 129.6 1.0 4.5 9.0 910.4 889.4 17.0 61.3 684.9 918.6 208.8 495.1 17.2 52.6 1.2 76.7 545.2 264.1 507.7 428.3 1413.2 42.6 3.4 582.2 989.6 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SPPL2B "IMP4, KIAA1532, PSL1" ENSG00000005206 "Signal peptide peptidase like 2B" Q8TCT7 19 2328615-2355095 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 109.1;Late spermatids: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005592, HPA039292" Approved Approved "Nucleoplasm,Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 20: HeLa - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" Centrosome "CAB005592: AB_325074, HPA039292: AB_2676429" "unprognostic (4.16e-2)" "unprognostic (2.97e-2)" "unprognostic (2.48e-2)" "prognostic favorable (5.00e-5)" "unprognostic (2.34e-1)" "unprognostic (1.54e-3)" "unprognostic (1.74e-1)" "unprognostic (7.93e-3)" "unprognostic (3.00e-1)" "unprognostic (1.72e-1)" "prognostic favorable (1.33e-4)" "unprognostic (3.29e-3)" "prognostic unfavorable (6.45e-4)" "unprognostic (2.26e-2)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (3.40e-2)" 23.1 23.2 13.7 16.7 13.6 29.1 27.4 15.5 18.6 28.4 17.4 43.4 41.6 26.4 4.4 22.5 34.0 10.7 21.6 11.8 12.1 35.9 33.0 22.2 20.7 19.2 15.6 27.2 50.7 11.0 63.8 10.4 15.5 32.5 9.2 7.1 27.2 9.8 25.3 28.9 52.6 5.9 13.2 39.1 33.9 63.5 15.1 12.0 40.5 3.1 9.9 21.9 20.9 16.4 16.6 25.9 10.9 19.5 8.8 8.9 27.8 21.1 6.1 7.6 8.1 18.2 18.4 15.7 19.4 9.9 7.1 21.7 3.6 7.3 2.3 18.4 16.0 10.4 44.7 24.9 16.5 18.6 13.1 13.1 8.2 7.2 5.2 11.9 10.7 32.2 17.3 39.0 4.7 18.4 20.2 23.6 20.4 14.7 10.5 33.4 5.8 43.9 8.3 41.0 19.4 18.3 21.2 12.8 16.7 7.1 21.3 30.8 24.3 13.8 9.7 35.3 16.9 51.0 20.1 16.7 17.3 21.4 24.5 11.5 7.7 7.4 6.2 7.7 4.4 8.2 5.6 6.0 9.4 12.5 6.9 7.7 3.3 6.4 5.4 17.0 6.0 6.4 13.7 13.6 15.5 18.6 11.8 12.1 19.2 15.6 15.5 13.2 15.1 16.4 23.6 3.2 17.2 57.1 30.8 0.0 6.5 0.0 8.0 26.1 21.6 21.5 6.0 20.0 5.0 25.8 47.9 50.6 18.8 79.5 1.9 16.6 51.4 39.3 22.2 14.4 40.7 14.5 25.3 11.5 20.8 14.2 109.1 25.5 7.0 39.9 13.2 15.1 11.8 32.0 30.3 63.2 0.0 9.4 0.0 107.7 14.9 10.8 0.0 9.4 8.0 13.2 19.6 39.7 35.2 10.4 49.9 15.8 11.5 7.3 57.8 7.9 10.9 39.4 0.0 15.0 11.7 57.0 13.5 10.8 0.0 42.8 11.0 36.4 49.8 6.0 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0;pituitary gland: 5.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 6.6;Enteroendocrine cells: 10.8;Excitatory neurons: 9.8;Inhibitory neurons: 10.4" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.9;TIME: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" 0.7 0.4 3.2 1.0 3.7 0.3 0.5 0.5 5.0 0.6 0.4 0.5 1.8 0.4 0.3 0.4 0.6 0.7 0.7 4.5 8.0 2.3 0.2 0.7 0.2 4.4 5.0 0.3 1.1 1.7 5.6 0.3 4.6 1.0 0.2 1.5 0.5 0.3 0.9 0.8 1.3 0.8 1.1 0.1 0.4 1.1 5.0 0.1 0.6 0.0 0.2 0.6 0.5 2.7 0.3 1.2 4.0 3.3 0.6 1.9 2.3 8.1 5.3 2.6 2.4 0.4 0.8 0.2 2.9 2.7 2.1 0.1 0.7 1.0 2.4 0.8 1.5 0.1 0.3 0.5 1.4 2.2 0.1 1.3 0.9 6.2 1.8 12.9 8.3 0.6 0.7 1.5 8.1 0.4 0.0 0.1 1.8 0.5 4.0 1.0 1.4 0.1 5.7 0.7 0.2 3.1 0.2 0.2 0.4 1.7 0.7 0.1 15.9 2.9 9.0 2.4 4.5 0.6 0.3 0.6 9.8 0.3 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 3.2 3.7 0.5 5.0 4.5 8.0 4.4 5.0 4.6 1.1 5.0 2.7 1.1 0.0 0.0 2.0 0.4 0.0 1.3 0.4 1.2 6.6 1.5 2.4 1.2 0.0 0.3 1.8 2.1 0.5 0.3 0.5 0.0 1.0 2.0 0.7 1.1 1.5 10.8 0.0 9.8 0.6 0.3 0.5 0.0 1.6 0.0 0.3 0.7 0.0 0.1 1.7 10.4 1.2 0.0 0.0 0.0 0.2 0.3 0.5 0.0 1.0 0.0 1.9 1.0 5.0 2.2 3.0 0.1 0.0 0.0 1.2 2.7 0.1 0.1 0.3 0.0 2.3 1.2 1.5 1.0 0.5 0.1 0.8 0.4 0.2 0.8 0.7 SPRYD3 FLJ14800 ENSG00000167778 "SPRY domain containing 3" Q8NCJ5 12 53064316-53079404 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039426, HPA039685" Enhanced Approved "Nucleoplasm,Vesicles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Cytosol" "Vesicles, Plasma membrane, Actin filaments" "HPA039426: AB_10673358, HPA039685: AB_2676623" "unprognostic (7.73e-3)" "unprognostic (6.55e-2)" "unprognostic (1.37e-2)" "unprognostic (5.05e-3)" "unprognostic (1.52e-2)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.27e-3)" "unprognostic (2.58e-1)" "unprognostic (1.83e-2)" "unprognostic (1.43e-2)" "unprognostic (2.64e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.78e-15)" "unprognostic (9.82e-2)" "unprognostic (5.27e-2)" "unprognostic (7.44e-3)" "unprognostic (1.41e-1)" 32.2 29.2 70.6 18.4 77.9 6.4 30.2 35.6 84.2 33.6 38.1 32.8 18.9 38.1 36.2 31.7 45.1 20.4 42.4 79.9 60.4 29.5 22.1 23.6 17.4 61.7 55.1 43.5 50.0 43.3 60.7 14.0 61.5 34.5 17.0 39.3 43.9 40.6 21.2 27.0 23.4 31.6 43.8 24.3 35.8 11.5 58.0 13.7 34.6 23.1 20.6 36.5 30.7 67.9 28.4 43.0 5.6 11.5 45.4 22.4 7.3 42.6 22.2 16.1 10.1 7.4 23.8 18.6 34.2 53.5 19.2 26.0 7.6 32.9 10.5 19.4 11.3 11.5 25.5 16.9 34.0 22.3 20.1 20.2 51.6 23.1 34.9 31.6 33.5 9.3 10.4 45.3 28.5 62.3 16.3 11.7 3.2 23.1 30.8 7.1 9.5 38.4 20.6 22.3 9.4 8.9 37.3 34.6 18.1 3.0 31.8 16.7 46.4 18.1 17.9 40.9 29.0 24.7 24.1 5.4 53.8 19.5 22.4 29.9 16.7 47.5 32.7 28.9 30.9 14.6 22.4 26.9 15.5 11.3 18.8 22.7 25.8 17.0 32.8 7.4 13.5 28.9 70.6 77.9 35.6 84.2 79.9 60.4 61.7 55.1 61.5 43.8 58.0 67.9 13.4 3.2 10.1 4.9 13.3 5.7 19.5 12.0 13.1 46.4 11.3 8.8 20.4 17.2 10.4 18.4 8.4 6.2 8.8 9.1 11.7 30.4 0.9 21.2 10.9 17.1 11.5 2.1 14.4 36.5 14.6 22.9 15.8 16.1 10.1 5.1 18.9 9.1 11.8 43.7 13.5 13.8 10.2 11.7 5.7 2.7 16.1 10.3 10.6 3.7 15.0 38.5 16.5 4.5 5.6 28.6 9.3 33.1 19.1 20.8 10.7 15.6 18.2 23.8 19.7 11.1 20.0 4.5 3.9 12.0 9.5 4.2 14.9 5.1 7.9 16.4 SPTBN2 SCA5 ENSG00000173898 "Spectrin beta, non-erythrocytic 2" O15020 11 66682497-66729226 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Disease variant, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.6;skin 1: 85.5" "Cell type enhanced" "Detected in many" "Collecting duct cells: 86.5;Cone photoreceptor cells: 104.3;Early spermatids: 30.9;Late spermatids: 77.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 45.6;NTERA-2: 49.1;SCLC-21H: 49.9;SK-BR-3: 52.3;T-47d: 67.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009844, HPA039293, HPA043529" Enhanced Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" Vesicles "CAB009844: AB_2194521, HPA039293: AB_2676430, HPA043529: AB_2678531" "unprognostic (9.34e-2)" "unprognostic (5.71e-2)" "unprognostic (4.89e-2)" "unprognostic (3.41e-3)" "unprognostic (4.91e-1)" "unprognostic (6.05e-3)" "unprognostic (4.45e-2)" "unprognostic (1.38e-2)" "unprognostic (7.25e-2)" "unprognostic (1.67e-2)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.64e-1)" "unprognostic (1.05e-3)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" "unprognostic (3.99e-2)" "unprognostic (1.00e-3)" 1.3 14.4 26.8 1.0 32.6 2.3 7.7 29.7 73.6 14.3 0.0 0.9 0.9 1.7 1.2 39.8 3.7 1.7 1.4 38.8 0.3 37.5 23.3 1.1 0.2 4.8 0.9 0.9 16.7 13.1 16.4 0.4 3.2 12.4 0.7 14.7 29.6 4.7 0.5 85.5 1.0 1.1 0.0 0.9 2.9 52.8 4.6 1.0 0.3 0.1 6.7 1.6 16.5 24.2 20.5 7.4 3.4 0.3 0.1 0.0 0.6 0.3 0.1 0.1 0.0 4.8 28.2 0.2 3.7 0.0 0.7 16.9 25.2 2.4 0.0 0.1 10.4 0.1 45.6 3.0 0.8 7.3 0.6 0.2 11.5 0.0 7.4 4.2 6.3 5.2 7.3 0.1 0.1 35.2 6.3 3.5 49.1 28.7 21.1 23.8 2.8 14.7 9.6 4.8 49.9 29.4 14.0 52.3 3.2 2.7 67.2 2.4 1.4 0.1 8.6 1.3 11.5 0.7 3.0 14.7 0.1 0.1 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 26.8 32.6 29.7 73.6 38.8 0.3 4.8 0.9 3.2 0.0 4.6 24.2 0.7 3.2 1.1 4.9 0.3 3.7 2.7 3.2 2.8 11.0 4.7 4.6 1.8 1.5 4.6 86.5 104.3 0.9 0.0 0.6 0.0 2.6 30.9 3.6 1.8 1.1 3.0 7.2 29.3 10.0 0.3 0.8 1.5 3.6 0.0 1.4 1.4 24.7 0.1 0.0 20.7 1.6 0.0 0.3 0.7 77.6 1.8 0.1 0.0 2.8 0.6 1.6 0.0 7.5 4.6 7.5 0.2 1.5 0.8 3.2 0.2 1.3 3.5 21.3 0.0 0.2 0.5 8.5 9.4 14.6 12.5 0.3 0.2 0.1 0.8 1.7 SRC "ASV, c-src, SRC1" ENSG00000197122 "SRC proto-oncogene, non-receptor tyrosine kinase" P12931 20 37344685-37406050 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Cell adhesion, Cell cycle, Host-virus interaction, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 42.0;Gastric mucus-secreting cells: 43.8;Langerhans cells: 46.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.4;non-classical monocyte: 2.3" "Group enriched" "Detected in many" 6 "dendritic cells: 1.4;monocytes: 2.4" "Cell line enhanced" "Detected in many" "A549: 110.8;HBEC3-KT: 102.6;RT4: 106.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004023, HPA030875" Approved Supported "Nucleoplasm,Plasma membrane,Cell Junctions,Cytosol" NA NA 3200000 "Cluster 51: Monocytes - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 15: RT4 - Unknown function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cell Junctions" "Nucleoplasm, Cytosol" "CAB004023: AB_2106059, HPA030875: AB_2673640" "unprognostic (5.58e-2)" "unprognostic (9.83e-2)" "unprognostic (3.56e-1)" "unprognostic (4.54e-3)" "unprognostic (1.52e-1)" "unprognostic (1.54e-2)" "prognostic unfavorable (4.90e-5)" "unprognostic (3.89e-2)" "unprognostic (7.04e-2)" "unprognostic (8.13e-2)" "unprognostic (1.54e-2)" "prognostic unfavorable (1.63e-4)" "prognostic unfavorable (1.22e-4)" "unprognostic (2.33e-2)" "unprognostic (4.72e-2)" "unprognostic (3.65e-2)" "prognostic favorable (5.22e-5)" 9.7 25.3 5.7 13.3 5.2 8.4 10.1 0.4 6.2 25.1 1.5 30.3 39.8 31.9 3.2 26.1 23.8 27.9 8.8 6.4 5.5 21.4 4.3 16.1 6.3 2.6 3.4 23.6 30.8 11.1 15.9 8.1 2.2 30.8 17.1 5.5 11.8 27.4 2.4 13.0 38.8 17.2 1.7 14.2 39.9 25.2 5.0 6.1 9.8 1.5 8.1 35.6 24.6 3.0 24.6 110.8 24.9 22.6 9.3 14.7 51.6 22.0 18.9 26.3 16.6 41.9 21.5 0.7 13.4 40.2 29.9 43.5 15.1 102.6 10.3 0.1 13.7 6.2 3.9 65.9 22.0 0.3 9.3 15.7 34.2 17.3 22.8 29.4 24.3 14.2 0.6 0.2 4.4 16.7 6.0 0.8 11.7 67.3 98.8 26.5 6.6 0.7 11.0 106.3 23.1 83.6 25.0 34.5 27.2 19.1 31.1 9.0 35.8 31.4 20.9 11.7 20.1 0.3 0.8 0.3 22.1 0.1 24.0 0.0 1.6 0.0 0.0 2.4 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 2.3 1.4 0.0 1.0 5.7 5.2 0.4 6.2 6.4 5.5 2.6 3.4 2.2 1.7 5.0 3.0 1.0 3.2 1.7 3.3 4.1 8.2 12.5 9.5 10.8 6.5 6.2 7.5 2.2 18.6 4.7 12.9 2.1 2.3 4.9 42.0 1.9 12.2 1.8 6.4 10.7 1.4 16.8 0.4 9.5 18.7 8.3 7.2 43.8 12.4 0.0 14.8 1.1 1.6 5.7 3.3 9.1 29.2 8.2 9.4 46.3 3.3 10.8 22.8 1.8 9.4 9.7 4.4 1.0 9.0 0.6 39.1 19.2 17.3 4.3 18.0 36.7 9.3 5.6 5.2 13.1 1.8 6.7 0.3 1.1 11.2 9.1 2.3 1.0 2.9 16.9 36.6 SRCIN1 "KIAA1684, p140Cap, SNIP" ENSG00000277363 "SRC kinase signaling inhibitor 1" Q9C0H9 17 38530031-38605952 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "brain: 66.2" "Cell type enhanced" "Detected in many" "Excitatory neurons: 66.3;Horizontal cells: 102.6;Inhibitory neurons: 58.5;Oligodendrocytes: 261.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SCLC-21H: 18.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009701, HPA063795" Enhanced Approved "Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA009701: AB_1857324, HPA063795: AB_2685124" "unprognostic (4.53e-1)" "unprognostic (4.05e-1)" "unprognostic (2.45e-2)" "unprognostic (3.24e-4)" "unprognostic (4.10e-2)" "unprognostic (3.72e-3)" "unprognostic (1.53e-1)" "unprognostic (2.84e-2)" "unprognostic (9.95e-2)" "unprognostic (1.80e-1)" "unprognostic (1.16e-4)" "unprognostic (1.00e-1)" "unprognostic (5.07e-3)" "unprognostic (9.51e-2)" "unprognostic (6.50e-2)" "unprognostic (2.67e-2)" "prognostic favorable (1.76e-4)" 1.9 1.3 11.1 0.1 32.1 0.2 3.1 22.1 29.9 2.1 0.0 4.2 0.6 1.0 0.6 2.2 3.0 0.0 2.1 13.6 14.1 1.6 13.9 1.2 0.2 36.4 28.8 0.5 6.6 2.4 15.5 0.2 33.7 2.3 0.2 0.4 7.8 0.8 0.5 6.1 1.4 0.1 13.8 0.6 2.1 1.4 29.9 0.1 0.7 0.0 0.0 1.7 1.1 66.2 0.4 0.4 0.6 2.7 0.1 0.0 0.1 0.0 0.1 0.2 0.0 0.5 0.4 1.1 0.9 0.0 0.7 1.0 1.2 0.2 0.1 1.1 1.2 0.0 0.5 1.2 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.5 0.1 3.9 0.0 2.4 0.0 0.0 1.5 0.5 0.0 0.1 0.0 0.1 0.4 1.7 18.0 2.0 0.0 1.0 0.7 0.6 1.8 0.4 0.0 0.0 1.2 0.0 0.0 0.8 0.2 0.0 0.1 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 32.1 22.1 29.9 13.6 14.1 36.4 28.8 33.7 13.8 29.9 66.2 0.4 0.0 1.1 5.5 0.3 0.8 1.0 0.3 0.6 31.5 6.1 5.1 2.9 21.5 0.3 3.7 0.0 0.1 0.3 0.7 0.0 2.7 0.2 9.0 1.0 0.6 9.7 0.0 66.3 0.2 0.1 0.9 0.0 0.9 0.0 2.7 0.4 12.6 0.4 102.6 58.5 1.8 2.0 0.0 0.4 0.6 0.6 0.1 0.0 3.7 0.0 1.8 0.0 6.6 261.8 0.3 0.3 0.4 0.1 1.4 0.6 0.2 5.3 3.4 0.0 0.4 0.5 0.9 2.1 0.8 0.9 0.1 0.2 0.0 1.5 1.6 SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 79.6" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favorable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" 12.5 12.0 10.4 2.5 11.5 3.7 12.2 11.0 12.4 12.9 9.2 7.3 3.8 6.8 4.2 26.1 5.6 10.3 9.3 10.7 10.1 9.6 14.5 10.5 2.5 11.0 11.2 3.1 20.2 7.0 5.9 4.0 10.8 7.4 4.1 1.5 16.4 2.9 6.3 15.4 7.0 2.6 10.9 6.8 9.7 3.3 10.9 6.0 7.6 5.4 6.0 10.0 14.7 12.7 9.7 4.3 10.3 10.1 29.4 20.4 5.6 10.4 9.3 2.4 5.4 6.5 19.5 21.2 11.7 11.0 11.1 7.0 5.3 7.9 3.9 6.6 17.1 12.3 5.2 15.8 9.2 23.7 6.1 17.6 14.5 5.4 5.3 7.8 14.4 38.5 21.2 47.7 21.1 10.8 36.0 10.3 13.0 53.2 9.3 11.4 3.3 14.0 12.8 7.9 16.0 9.1 10.7 79.6 8.3 9.0 9.4 17.9 8.3 25.0 4.7 2.0 8.1 28.6 15.8 7.9 34.1 29.5 25.9 25.6 35.8 11.7 16.1 56.5 18.6 12.5 12.0 15.2 30.2 12.7 10.2 14.4 1.8 8.6 59.5 61.7 12.5 23.1 10.4 11.5 11.0 12.4 10.7 10.1 11.0 11.2 10.8 10.9 10.9 12.7 25.4 9.6 15.9 4.6 7.8 13.6 13.3 245.5 5.2 4.9 43.8 29.3 5.3 34.3 245.2 5.5 4.2 27.0 21.2 12.2 3.9 93.4 3.2 51.2 31.0 19.6 12.0 14.9 11.1 105.4 106.0 16.2 13.3 105.9 14.0 6.7 17.5 18.6 63.4 10.1 17.1 22.6 57.0 32.4 34.1 0.5 1.8 27.6 24.9 4.7 31.3 21.9 18.6 8.5 23.4 155.5 10.0 5.7 16.8 17.5 9.4 18.4 195.0 3.9 13.1 13.3 28.2 3.5 20.1 32.7 29.7 7.5 7.2 15.4 23.3 108.6 SRPK1 SFRSK1 ENSG00000096063 "SRSF protein kinase 1" Q96SB4 6 35832966-35921342 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Chromosome partition, Differentiation, Host-virus interaction, mRNA processing, mRNA splicing" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 379.9;Late spermatids: 599.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 61.0" "Lineage enriched" "Detected in all" 4 "granulocytes: 61.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016431, HPA056486" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA016431: AB_1857478, HPA056486: AB_2683148" "unprognostic (4.65e-3)" "unprognostic (6.82e-3)" "unprognostic (2.54e-3)" "unprognostic (1.01e-3)" "unprognostic (7.74e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (7.90e-6)" "unprognostic (1.23e-2)" "unprognostic (2.54e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (6.53e-5)" "unprognostic (7.28e-2)" "unprognostic (2.21e-3)" "unprognostic (9.24e-2)" "unprognostic (4.43e-1)" "unprognostic (1.01e-1)" "unprognostic (7.55e-3)" 8.7 6.0 6.4 18.1 8.2 41.7 14.5 10.0 14.8 12.5 6.8 31.2 25.2 12.7 9.3 23.9 8.6 11.9 8.3 8.9 3.7 16.7 16.0 12.9 19.7 4.0 4.1 8.7 23.3 14.5 9.0 14.5 4.3 9.6 35.6 25.8 16.1 10.9 20.0 26.7 23.6 14.2 2.4 17.8 18.0 44.7 5.2 19.9 8.7 12.6 24.3 31.0 16.2 11.6 104.1 39.2 54.9 82.4 30.2 39.3 69.0 62.1 60.1 57.3 60.2 109.0 34.1 139.0 51.8 39.1 65.5 51.3 110.3 74.2 100.6 96.2 79.9 73.5 42.6 93.8 26.7 111.3 34.0 25.6 39.3 66.0 84.7 44.6 72.3 76.4 157.7 55.6 48.2 36.8 111.1 80.8 45.9 62.9 42.7 77.8 67.3 84.1 56.8 169.5 117.5 42.9 65.4 59.3 42.5 55.2 33.3 70.3 54.8 52.4 41.3 37.2 78.6 33.1 78.6 128.5 20.9 124.3 48.1 61.0 4.4 30.6 8.5 5.3 12.1 8.6 11.2 11.5 5.9 6.9 9.2 10.0 50.9 11.2 7.6 3.3 14.9 6.3 6.4 8.2 10.0 14.8 8.9 3.7 4.0 4.1 4.3 2.4 5.2 11.6 26.6 9.6 25.8 18.6 40.0 42.3 119.3 91.0 67.7 36.8 25.8 22.7 28.7 14.3 51.4 22.0 37.5 54.3 33.1 51.6 29.4 55.4 379.9 29.9 40.2 29.2 46.2 46.7 74.2 68.2 53.2 25.1 46.9 54.0 7.6 44.1 13.2 41.8 21.6 10.1 50.0 50.8 32.6 16.3 19.9 599.1 22.1 20.0 16.0 24.4 31.5 16.8 32.0 30.2 29.7 100.4 47.9 24.8 68.0 117.9 50.8 59.4 33.8 92.9 6.6 17.8 48.9 197.3 100.4 126.8 41.8 39.7 43.6 33.7 90.7 162.6 SRPRB "APMCF1, SR-beta" ENSG00000144867 "SRP receptor subunit beta" Q9Y5M8 3 133784023-133825772 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011173 Approved Approved "Plasma membrane" NA NA 12000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "HPA011173: AB_1857484" "unprognostic (5.44e-2)" "unprognostic (1.32e-1)" "unprognostic (6.40e-2)" "unprognostic (1.58e-2)" "unprognostic (2.61e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.99e-1)" "unprognostic (3.60e-2)" "unprognostic (6.07e-3)" "unprognostic (8.45e-2)" "unprognostic (1.31e-2)" "unprognostic (3.79e-2)" "unprognostic (5.08e-2)" "unprognostic (7.37e-2)" "unprognostic (6.47e-2)" "unprognostic (2.26e-2)" 20.4 26.8 21.1 18.4 23.3 14.1 24.7 23.2 24.6 26.6 26.4 23.1 19.0 14.4 47.9 29.9 17.9 13.3 16.9 21.1 23.7 26.6 52.9 14.8 15.3 24.5 24.4 13.8 83.2 27.6 25.4 16.0 24.5 18.2 26.1 6.8 49.9 23.7 19.0 15.4 15.4 21.0 22.4 15.5 24.4 26.8 23.1 10.7 26.1 16.5 28.9 23.7 13.8 28.9 44.8 37.5 22.6 72.7 91.8 62.3 45.6 97.4 49.4 50.2 44.3 73.7 34.6 90.4 131.5 72.4 51.2 64.8 69.8 50.9 47.7 57.8 59.6 80.6 34.9 65.2 110.8 124.5 56.7 57.3 83.3 46.2 135.9 28.1 43.5 43.6 68.1 96.9 55.5 65.6 40.9 55.5 43.8 120.3 63.8 49.1 43.5 190.8 61.9 32.1 74.7 32.7 77.3 66.6 28.3 17.0 76.9 55.1 46.0 51.9 29.0 82.8 54.0 118.8 131.5 131.4 45.3 82.9 56.9 13.1 30.5 3.9 54.3 41.1 73.0 38.9 45.4 47.9 36.3 36.7 43.3 51.9 2.2 41.5 27.5 53.8 29.1 50.3 21.1 23.3 23.2 24.6 21.1 23.7 24.5 24.4 24.5 22.4 23.1 28.9 16.8 16.0 20.6 15.3 43.4 37.7 32.0 38.2 11.4 6.5 36.4 22.0 26.6 37.1 32.8 36.8 12.5 65.4 29.1 14.2 11.7 46.0 68.9 18.7 51.2 26.3 32.2 21.7 16.0 67.4 71.2 40.6 28.5 30.1 32.4 19.8 18.9 88.4 49.4 6.7 15.7 58.8 36.7 19.7 23.1 35.9 32.0 20.6 35.6 8.4 16.4 17.2 20.6 17.6 92.6 36.0 17.7 27.8 146.0 52.3 20.0 33.0 24.3 9.4 13.1 38.2 30.2 60.1 40.6 52.1 31.5 51.7 26.1 52.9 43.9 28.5 SRRM3 FLJ37078 ENSG00000177679 "Serine/arginine repetitive matrix 3" 7 76201896-76287288 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "brain: 56.0;retina: 27.2" "Group enriched" "Detected in many" 7 "Bipolar cells: 153.1;Cone photoreceptor cells: 479.6;Excitatory neurons: 139.1;Horizontal cells: 171.6;Inhibitory neurons: 144.4;Rod photoreceptor cells: 421.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 10.9;SH-SY5Y: 8.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019337 Approved "Plasma membrane,Intermediate filaments,Microtubules" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Intermediate filaments, Microtubules" "HPA019337: AB_1848909" "unprognostic (1.65e-1)" "unprognostic (1.96e-1)" "unprognostic (8.37e-3)" "unprognostic (4.93e-2)" "unprognostic (1.81e-1)" "unprognostic (1.39e-1)" "unprognostic (8.53e-2)" "unprognostic (6.51e-2)" "unprognostic (1.89e-3)" "unprognostic (1.62e-2)" "unprognostic (5.07e-3)" "unprognostic (6.37e-2)" "unprognostic (3.73e-3)" "unprognostic (5.05e-1)" "unprognostic (2.98e-1)" "unprognostic (1.84e-1)" "unprognostic (5.15e-2)" 0.0 2.1 6.0 0.1 13.2 0.0 0.0 56.0 30.7 0.1 0.0 0.3 0.1 0.2 0.2 0.1 0.0 0.0 0.1 4.8 0.2 0.0 0.0 0.0 0.0 41.5 3.2 0.2 0.3 0.3 8.9 0.0 40.1 0.1 0.1 27.2 0.1 0.0 0.1 0.0 0.1 0.0 1.6 0.0 0.4 2.1 0.9 0.0 0.0 0.0 0.0 0.0 0.2 4.7 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 8.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 13.2 56.0 30.7 4.8 0.2 41.5 3.2 40.1 1.6 0.9 4.7 0.3 0.0 0.0 8.1 0.0 2.0 6.4 1.9 7.4 153.1 1.8 0.5 6.9 1.5 1.2 0.0 479.6 0.4 0.0 0.2 0.0 2.0 22.2 0.5 4.2 1.2 12.1 0.0 139.1 2.4 8.1 4.8 0.5 1.0 0.0 12.0 1.8 0.0 0.5 171.6 144.4 0.1 2.0 0.0 0.8 32.2 2.1 0.2 3.6 5.6 0.0 15.9 0.0 18.6 4.9 0.9 0.1 2.2 0.0 2.2 0.0 0.4 0.2 421.8 0.0 1.2 2.0 8.6 3.1 4.9 1.1 2.2 0.1 0.2 0.0 4.9 SSH1 "KIAA1298, SSH1L" ENSG00000084112 "Slingshot protein phosphatase 1" Q8WYL5 12 108778191-108857590 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Actin-binding, Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "WM-115: 63.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019845 Uncertain Uncertain "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nucleoplasm, Cytosol" "HPA019845: AB_1857497" "unprognostic (1.18e-3)" "unprognostic (3.00e-1)" "unprognostic (2.49e-1)" "unprognostic (2.70e-2)" "unprognostic (9.40e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (5.80e-5)" "unprognostic (3.28e-2)" "unprognostic (3.69e-2)" "unprognostic (1.72e-3)" "unprognostic (7.12e-2)" "unprognostic (3.42e-1)" "unprognostic (1.71e-2)" "unprognostic (1.41e-1)" "unprognostic (8.66e-2)" "unprognostic (9.55e-2)" "unprognostic (6.22e-2)" 6.6 5.1 5.6 5.1 5.1 7.9 5.0 9.2 5.5 5.8 7.2 7.2 2.9 5.9 4.0 5.5 5.3 5.3 7.8 5.7 5.3 6.7 5.5 11.8 4.1 5.8 5.7 5.0 4.3 5.4 5.2 5.2 5.2 5.2 4.1 5.7 3.9 4.8 11.9 4.6 5.1 5.5 5.0 7.5 4.9 3.5 5.1 3.6 5.3 6.5 4.2 6.0 5.2 5.1 9.9 12.7 8.2 6.4 15.1 12.8 7.2 12.8 26.1 11.0 9.7 6.4 4.6 4.9 8.7 29.0 18.8 9.8 4.9 20.7 8.9 9.9 4.8 11.3 6.0 4.0 8.1 5.8 28.4 17.7 7.0 10.0 22.0 27.1 10.3 5.6 2.5 3.6 29.1 5.4 6.6 8.0 5.8 3.8 10.3 4.6 9.8 6.1 4.5 17.1 6.1 8.1 11.0 2.8 24.2 11.2 3.9 4.8 8.1 19.6 8.4 11.9 7.1 7.3 7.0 5.6 10.3 4.5 63.1 1.8 0.9 2.0 1.0 1.5 0.9 0.6 0.5 0.9 0.6 0.6 0.4 0.5 2.1 0.7 1.2 0.7 0.6 0.5 5.6 5.1 9.2 5.5 5.7 5.3 5.8 5.7 5.2 5.0 5.1 5.1 34.5 9.6 16.1 26.1 6.3 9.4 20.8 23.6 19.4 12.9 6.9 6.6 25.1 11.5 12.7 14.7 16.7 6.0 18.5 8.2 5.9 8.4 2.2 10.8 17.1 52.2 5.4 7.8 27.3 8.2 4.4 14.0 13.7 16.9 20.8 12.0 29.3 15.2 12.3 11.8 35.4 5.4 0.0 23.0 20.3 5.0 6.5 21.1 12.4 55.3 33.7 7.8 14.4 14.1 14.8 12.3 2.4 12.8 13.1 21.8 4.0 6.7 9.0 19.1 6.6 17.8 18.1 1.4 7.7 13.2 8.9 2.3 17.9 7.6 7.8 13.9 SSH3 "FLJ10928, FLJ20515" ENSG00000172830 "Slingshot protein phosphatase 3" Q8TE77 11 67303478-67312607 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 11.6;eosinophil: 11.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 11.6" "Cell line enhanced" "Detected in many" "HaCaT: 64.9;MCF7: 64.1;RT4: 111.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019949, HPA019957" Approved Approved "Nuclear speckles,Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Nuclear speckles, Cytosol" "Plasma membrane, Actin filaments" "HPA019949: AB_1857498, HPA019957: AB_1857499" "unprognostic (4.38e-2)" "unprognostic (1.37e-1)" "unprognostic (3.50e-3)" "unprognostic (3.73e-2)" "unprognostic (2.61e-3)" "unprognostic (9.30e-2)" "unprognostic (2.99e-1)" "unprognostic (1.84e-1)" "unprognostic (1.63e-1)" "unprognostic (2.45e-2)" "prognostic unfavorable (2.89e-4)" "unprognostic (1.50e-1)" "unprognostic (2.06e-2)" "unprognostic (1.47e-1)" "unprognostic (3.20e-1)" "unprognostic (4.94e-3)" "unprognostic (6.78e-3)" 14.4 7.8 8.9 4.0 12.0 9.3 16.2 14.1 11.6 25.9 9.5 19.3 13.3 16.0 7.5 41.9 18.3 11.5 12.5 9.1 10.1 13.1 10.9 12.7 3.1 14.6 10.8 23.5 15.3 9.8 9.7 6.5 13.2 29.9 9.3 1.2 26.2 28.8 6.8 25.2 15.0 6.1 12.3 9.4 20.1 2.3 11.5 1.9 16.3 3.8 4.8 37.4 32.5 14.9 17.3 18.7 0.4 0.6 11.4 11.8 18.8 10.3 13.7 5.6 5.1 21.2 46.8 1.0 32.5 10.5 11.9 64.9 6.0 46.4 2.8 3.6 6.3 4.3 32.2 9.9 8.2 0.9 16.0 12.2 40.5 8.3 8.3 12.9 6.3 0.4 0.1 1.5 6.2 64.1 0.8 7.3 4.2 48.9 13.8 20.6 0.6 3.1 18.2 111.2 3.7 5.8 24.8 41.0 12.8 6.3 57.1 15.3 10.4 4.5 9.8 12.7 2.7 1.5 0.9 0.5 12.7 6.9 4.9 11.6 1.5 11.1 2.0 2.3 1.7 0.2 1.9 1.7 1.7 0.1 0.8 0.8 4.4 1.5 1.1 1.1 1.8 1.1 8.9 12.0 14.1 11.6 9.1 10.1 14.6 10.8 13.2 12.3 11.5 14.9 7.6 3.2 8.7 8.5 0.9 7.0 20.8 25.2 11.4 0.8 21.3 17.3 3.8 20.0 23.4 16.5 0.0 15.1 3.3 28.3 3.9 19.4 0.1 8.3 5.6 4.7 3.6 5.2 4.2 21.6 24.9 8.0 20.9 17.8 3.8 8.1 3.9 5.0 7.7 1.7 5.3 14.4 24.4 6.2 3.1 0.6 13.1 4.8 8.8 2.8 9.2 4.8 7.2 0.0 15.9 20.0 21.0 12.0 0.7 15.4 20.2 7.4 11.6 0.5 0.0 4.9 9.2 0.5 0.4 27.0 10.4 15.7 4.4 5.3 21.4 26.8 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.9;kidney: 2.9;pituitary gland: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 15.4;PC-3: 54.7" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 1.5 2.9 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.0 7.3 0.0 0.1 0.7 0.0 0.2 1.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 54.7 0.0 2.1 0.6 0.0 2.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.3 1.5 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SSX2IP hMsd1 ENSG00000117155 "SSX family member 2 interacting protein" Q9Y2D8 1 84643706-84690803 "Predicted intracellular proteins" "Cell adhesion, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 118.7;testis: 105.7" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 260.6;Early spermatids: 774.9;Late spermatids: 1095.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075946 Supported Approved "Cell Junctions" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Cell Junctions" "HPA075946: " "unprognostic (5.18e-3)" "unprognostic (2.13e-1)" "prognostic favorable (1.45e-4)" "unprognostic (2.83e-2)" "unprognostic (2.75e-1)" "unprognostic (3.29e-2)" "unprognostic (1.28e-3)" "unprognostic (7.73e-2)" "unprognostic (2.38e-1)" "unprognostic (3.37e-2)" "unprognostic (9.49e-2)" "unprognostic (1.39e-1)" "unprognostic (1.96e-2)" "unprognostic (7.23e-3)" "unprognostic (2.08e-2)" "unprognostic (2.45e-2)" "unprognostic (3.46e-2)" 1.9 3.1 8.2 5.8 13.1 14.9 5.1 12.9 23.4 6.8 4.4 8.1 43.2 9.3 22.6 6.4 7.2 8.7 9.4 13.8 3.6 16.5 14.5 3.9 6.4 1.1 1.4 2.0 7.1 9.2 9.6 6.3 1.4 12.7 7.8 118.7 6.9 11.8 3.5 6.5 26.8 10.7 0.0 5.4 7.1 105.7 1.5 12.1 8.2 2.6 6.3 5.7 3.5 11.9 39.1 19.0 15.1 27.7 5.0 15.7 18.4 65.6 33.2 28.3 22.7 13.7 8.4 38.6 11.3 55.8 36.5 21.4 27.0 21.2 39.5 7.7 23.0 36.4 22.2 11.9 10.3 32.1 2.9 6.7 34.1 31.9 20.1 18.9 9.7 14.7 76.5 14.1 18.1 15.0 22.5 12.7 22.3 7.4 29.6 15.1 66.0 17.0 29.5 22.3 29.4 36.7 18.4 29.6 32.9 9.5 17.2 16.4 2.9 26.8 39.2 36.9 65.9 14.7 18.7 42.0 22.4 28.2 16.9 0.8 0.8 3.9 8.2 1.9 4.5 1.2 2.6 3.3 3.5 1.2 3.3 5.1 1.1 4.6 2.6 4.5 1.5 3.9 8.2 13.1 12.9 23.4 13.8 3.6 1.1 1.4 1.4 0.0 1.5 11.9 4.4 3.2 3.0 38.2 3.7 10.5 8.6 8.7 12.5 45.6 10.5 7.0 36.8 21.5 7.3 11.0 260.6 5.3 23.9 3.9 7.9 7.3 774.9 14.9 8.9 5.0 8.4 46.7 108.5 12.0 1.9 15.7 5.6 11.6 4.5 4.2 3.6 14.9 2.7 20.2 70.2 9.3 2.0 1.9 5.6 1095.3 15.8 24.1 5.4 18.7 3.5 187.4 15.5 16.6 23.9 9.4 4.6 11.3 12.7 4.3 19.7 44.9 13.3 158.0 0.0 4.2 7.3 71.7 53.6 13.6 9.8 0.5 8.4 2.0 10.7 4.2 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 STAB1 "CLEVER-1, FEEL-1, FELE-1, FEX1, KIAA0246, SCARH2, STAB-1" ENSG00000010327 "Stabilin 1" Q9NY15 3 52495338-52524495 "Predicted membrane proteins, Transporters" "Inflammatory response" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 439.5" "Cell type enriched" "Detected in many" 4 "Hepatic stellate cells: 745.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 59 "classical monocyte: 9.4;intermediate monocyte: 5.7;myeloid DC: 2.5" "Group enriched" "Detected in many" 60 "dendritic cells: 2.5;monocytes: 9.4" "Group enriched" "Detected in some" 46 "HUVEC TERT2: 103.1;NB-4: 146.9;TIME: 128.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005434 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 96000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" Cytosol "Nucleoplasm, Plasma membrane" "HPA005434: AB_1080097" "unprognostic (1.18e-1)" "unprognostic (2.89e-1)" "prognostic unfavorable (7.59e-4)" "unprognostic (3.63e-2)" "unprognostic (1.21e-1)" "unprognostic (1.49e-2)" "unprognostic (1.08e-2)" "unprognostic (2.23e-1)" "unprognostic (2.38e-1)" "unprognostic (4.00e-3)" "unprognostic (2.66e-2)" "unprognostic (3.19e-1)" "prognostic unfavorable (3.88e-7)" "unprognostic (3.16e-2)" "unprognostic (9.40e-2)" "unprognostic (4.70e-2)" "unprognostic (1.08e-1)" 194.2 160.4 41.0 50.4 42.9 13.8 84.5 41.4 58.3 54.4 62.8 87.7 29.6 45.3 8.5 29.2 79.3 25.8 74.6 41.9 44.4 85.6 102.1 104.7 12.9 50.0 48.4 32.2 32.2 5.0 52.0 55.4 53.7 57.6 31.0 0.6 45.7 16.0 25.9 24.0 95.1 33.8 43.0 439.5 53.2 21.0 65.3 6.8 55.1 4.6 8.2 105.7 48.6 47.8 0.1 0.0 0.1 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.7 0.2 0.2 0.6 0.0 0.0 1.8 0.1 0.0 0.1 0.0 103.1 0.1 0.3 0.1 0.0 0.0 0.0 146.9 0.0 0.2 0.2 0.1 0.1 0.3 0.0 0.0 0.4 0.4 0.0 0.3 0.0 0.1 0.0 0.0 128.8 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.1 0.1 0.0 9.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 41.0 42.9 41.4 58.3 41.9 44.4 50.0 48.4 53.7 43.0 65.3 47.8 31.3 0.0 3.8 0.0 5.5 6.0 0.6 0.0 1.8 1.0 1.5 2.7 2.4 11.5 0.0 3.7 0.0 1.7 1.9 0.0 0.0 0.0 0.5 0.4 0.5 43.0 1.2 21.5 0.3 0.0 2.0 3.3 0.5 0.3 18.3 0.0 745.0 19.7 130.7 0.0 0.3 0.0 0.0 185.4 30.3 2.9 4.4 147.0 12.4 30.0 21.9 0.5 2.1 0.5 0.1 0.0 0.0 20.3 2.0 0.2 0.0 0.8 0.0 0.1 19.7 2.0 1.4 0.9 2.2 1.5 4.8 2.2 2.3 0.5 0.0 0.2 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STAMBP AMSH ENSG00000124356 "STAM binding protein" O95630 2 73828916-73873659 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 12 "LHCN-M2: 1108.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035800, HPA035801" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 18000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 80: Striated muscle - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA035800: AB_10670591, HPA035801: AB_2732470" "unprognostic (1.86e-2)" "unprognostic (1.14e-1)" "unprognostic (2.16e-1)" "prognostic unfavorable (4.70e-5)" "unprognostic (6.13e-2)" "unprognostic (2.08e-3)" "unprognostic (3.73e-2)" "unprognostic (1.71e-1)" "unprognostic (6.58e-2)" "unprognostic (2.96e-2)" "prognostic unfavorable (5.79e-4)" "unprognostic (1.01e-1)" "unprognostic (2.29e-1)" "unprognostic (7.72e-2)" "unprognostic (2.63e-1)" "unprognostic (1.43e-1)" "unprognostic (2.89e-1)" 15.6 11.6 21.7 14.6 30.6 13.3 20.2 29.7 23.8 19.3 19.3 21.5 20.7 20.6 15.5 25.4 18.3 16.9 22.3 20.6 24.5 21.9 19.0 15.7 19.3 31.3 28.0 17.7 12.2 24.3 9.3 17.3 30.4 22.1 23.2 14.6 21.5 15.6 37.4 16.7 20.4 21.3 27.9 14.9 18.2 15.8 27.1 23.2 22.6 42.8 21.6 16.8 16.0 38.6 39.0 44.0 34.0 31.6 31.1 37.2 39.1 23.3 31.7 42.1 40.3 73.7 35.9 32.2 35.8 19.8 55.7 30.0 36.6 81.7 47.6 56.6 41.3 43.3 29.1 58.1 43.4 35.8 50.0 30.1 57.6 49.6 70.7 53.5 25.1 43.7 47.9 47.8 1108.9 46.8 55.9 32.4 54.9 55.1 22.7 38.6 89.4 46.1 45.2 43.0 62.0 45.8 28.4 34.6 49.1 36.4 32.3 21.4 22.0 37.5 44.5 22.9 41.9 44.8 46.9 24.9 46.4 38.1 44.7 30.7 18.9 34.2 15.9 21.4 17.2 21.5 18.3 15.6 19.9 19.3 18.9 14.4 27.6 22.3 19.9 19.5 25.8 14.9 21.7 30.6 29.7 23.8 20.6 24.5 31.3 28.0 30.4 27.9 27.1 38.6 22.1 19.2 17.7 22.9 21.5 16.3 28.9 61.7 31.3 22.3 28.8 27.7 41.1 28.6 34.4 25.8 12.5 43.0 27.4 48.7 49.0 37.9 80.8 35.6 37.3 21.4 10.3 34.9 18.5 36.3 32.5 26.0 18.8 45.8 52.6 21.2 17.5 41.1 33.0 26.9 22.1 36.4 40.7 27.7 16.2 125.0 32.6 25.2 7.2 16.9 34.1 24.9 25.7 26.2 67.2 44.5 41.8 34.6 21.5 40.9 57.2 68.8 24.5 21.0 39.5 28.2 27.2 33.1 44.2 44.5 21.6 44.5 21.4 27.5 34.3 27.1 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 60.5;Microglial cells: 32.8;Spermatocytes: 40.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040202 Uncertain Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 23.8 5.5 10.4 6.5 5.3 2.5 2.6 9.0 2.7 0.0 8.7 6.4 4.2 0.9 4.4 2.2 4.1 8.0 6.2 1.4 1.8 1.8 3.6 16.2 1.1 0.5 12.7 2.3 3.4 5.5 1.2 2.6 1.7 9.7 4.4 1.4 1.1 0.7 3.7 7.3 3.0 1.9 7.2 5.1 18.0 0.5 7.1 1.2 1.5 12.2 6.4 2.5 5.6 14.8 16.5 1.0 0.6 14.4 27.7 0.0 31.5 28.9 19.0 16.3 0.3 25.6 18.6 2.3 15.6 12.3 6.4 4.1 4.5 17.9 16.3 10.8 4.6 10.4 0.9 10.3 20.2 5.7 10.6 1.4 31.6 9.6 18.4 0.6 20.9 0.0 7.3 50.0 3.0 34.2 21.5 6.6 13.3 14.1 3.4 13.0 3.8 6.5 4.7 9.6 11.9 3.7 1.1 37.5 3.6 2.3 4.1 4.9 17.0 12.4 20.7 19.9 17.7 19.7 17.2 18.2 19.4 16.9 9.5 1.0 8.1 10.7 1.1 14.1 17.7 15.5 13.7 1.7 14.9 16.6 10.0 1.4 23.6 0.5 27.9 28.3 8.0 5.5 6.5 2.6 9.0 6.2 1.4 1.1 0.5 2.6 1.9 0.5 5.6 2.3 0.0 4.5 10.7 16.7 9.6 5.3 1.4 1.2 3.6 2.3 1.4 8.6 0.0 0.2 5.5 0.0 0.1 18.8 7.6 0.0 1.3 54.3 1.9 6.5 1.8 9.1 3.4 60.5 1.8 0.1 7.7 3.1 1.4 5.1 7.4 1.8 2.4 3.7 6.7 26.2 9.3 4.1 1.3 9.6 20.7 7.2 3.1 0.0 32.8 1.0 9.3 12.3 26.2 1.9 1.9 2.8 1.5 14.2 1.9 7.9 0.8 5.0 0.4 0.0 20.4 6.4 40.2 2.5 5.9 11.4 0.1 17.6 14.9 14.2 2.9 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STAT2 STAT113 ENSG00000170581 "Signal transducer and activator of transcription 2" P52630 12 56341597-56360167 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003858, HPA018888" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "Plasma membrane" "CAB003858: AB_562227, HPA018888: AB_1857550" "unprognostic (3.03e-1)" "unprognostic (8.59e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (7.27e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (4.12e-3)" "unprognostic (1.56e-1)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.78e-13)" "unprognostic (1.88e-1)" "unprognostic (5.56e-2)" "unprognostic (2.77e-1)" "unprognostic (1.46e-3)" 17.3 6.3 2.6 19.2 2.3 7.8 10.3 2.7 3.1 18.7 2.9 10.7 10.7 11.3 5.6 11.1 12.9 20.1 8.1 3.1 2.3 8.4 20.6 22.8 19.6 4.2 2.0 17.4 9.9 12.4 8.6 15.9 3.1 10.3 12.5 5.6 18.1 9.9 4.0 7.8 13.0 21.8 5.9 25.2 10.3 4.0 4.6 19.9 10.7 8.4 20.1 18.4 5.6 6.2 15.5 8.5 11.8 12.5 98.3 58.6 26.1 19.4 94.0 92.4 93.1 8.7 16.4 17.9 22.6 38.6 24.2 14.9 21.0 15.1 18.0 13.8 4.7 27.2 7.6 9.3 58.8 5.0 20.2 86.8 13.4 19.5 22.8 70.5 25.6 14.3 15.2 44.7 35.1 9.4 7.3 3.5 5.2 15.1 9.8 6.9 22.1 17.1 21.3 18.1 4.2 10.1 31.5 18.8 43.1 22.7 16.4 17.7 11.2 22.2 10.7 8.0 3.1 32.5 32.9 9.8 30.3 7.2 9.9 14.8 17.2 11.3 7.7 22.8 7.9 5.2 7.4 7.7 11.6 7.5 5.2 5.1 6.8 4.8 18.3 10.2 9.8 13.1 2.6 2.3 2.7 3.1 3.1 2.3 4.2 2.0 3.1 5.9 4.6 6.2 36.0 12.8 41.7 40.5 24.0 14.3 10.3 13.7 17.1 17.0 17.4 15.0 11.1 15.7 24.4 18.4 20.9 11.2 28.1 23.8 1.9 14.0 13.8 20.7 36.4 26.5 15.5 8.6 29.8 10.7 24.5 27.6 19.9 26.6 10.1 24.6 27.8 64.8 25.9 3.3 28.6 16.8 6.1 50.9 25.6 43.7 19.6 45.2 32.0 24.4 42.3 10.4 18.6 27.6 111.8 11.9 21.9 17.3 24.4 11.4 24.0 10.7 24.2 21.8 26.3 20.3 22.5 3.2 5.0 12.5 14.5 11.1 20.1 13.7 14.8 13.2 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STIP1 "HOP, STI1" ENSG00000168439 "Stress induced phosphoprotein 1" P31948 11 64185272-64204543 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 340.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017448, HPA039291, HPA044062" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 3600000 "Cluster 27: Non-specific - Gene expression" "Cluster 47: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" Cytosol "CAB017448: AB_10618972, HPA039291: AB_2676428, HPA044062: AB_2678795" "unprognostic (2.49e-3)" "unprognostic (6.04e-2)" "unprognostic (1.57e-1)" "unprognostic (4.65e-2)" "unprognostic (1.03e-1)" "prognostic unfavorable (1.23e-4)" "prognostic unfavorable (6.18e-8)" "unprognostic (2.16e-3)" "unprognostic (4.56e-2)" "unprognostic (1.12e-2)" "unprognostic (3.56e-2)" "unprognostic (3.04e-3)" "unprognostic (1.70e-1)" "unprognostic (6.72e-2)" "unprognostic (8.23e-2)" "unprognostic (7.16e-2)" "unprognostic (2.99e-2)" 68.0 128.0 114.5 70.2 119.9 61.3 49.7 124.6 340.6 69.5 122.1 72.9 40.4 74.1 49.0 79.5 72.4 43.5 98.5 120.2 133.4 86.7 68.9 70.8 72.9 124.0 131.3 87.6 53.3 61.4 71.7 77.5 139.2 60.7 56.0 62.9 56.1 56.1 140.3 60.5 53.9 66.7 123.6 69.0 66.1 126.3 134.2 66.2 57.6 92.2 88.2 81.2 63.8 159.4 321.0 486.3 298.1 251.7 161.8 108.1 271.5 277.2 150.1 393.9 228.1 361.3 265.2 371.1 322.9 220.3 475.4 329.7 745.4 280.3 427.6 302.1 311.7 521.5 302.6 336.7 142.8 278.7 325.1 109.4 174.5 327.1 242.7 162.4 284.2 276.1 537.2 209.5 232.1 468.8 432.0 388.6 366.4 306.0 407.2 418.3 279.1 385.6 282.8 271.8 242.7 217.3 314.4 338.9 266.7 310.3 357.1 194.0 253.8 252.0 310.9 333.1 389.0 189.8 434.0 388.0 328.8 282.6 374.1 61.0 66.8 57.4 87.6 95.1 88.2 85.9 65.5 79.5 69.9 68.5 72.7 81.6 20.0 108.2 114.6 58.1 66.1 119.1 114.5 119.9 124.6 340.6 120.2 133.4 124.0 131.3 139.2 123.6 134.2 159.4 31.3 44.8 32.9 7.8 40.0 80.4 184.1 61.5 40.9 37.5 32.5 29.8 46.1 31.5 59.1 20.2 41.7 124.8 39.8 38.3 49.0 76.3 31.0 65.8 48.6 45.9 67.3 69.0 9.5 55.2 146.1 49.6 24.5 51.1 79.3 47.8 14.3 27.4 91.5 63.9 14.9 39.9 97.6 21.9 90.3 77.5 27.4 46.7 62.2 12.2 51.8 36.9 53.5 11.1 17.2 69.5 32.7 39.9 56.4 75.7 22.3 39.6 85.8 36.7 26.3 36.1 65.4 96.3 118.6 47.6 72.0 211.0 67.0 62.8 48.6 95.3 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STK16 "MPSK, PKL12" ENSG00000115661 "Serine/threonine kinase 16" O75716 2 219245455-219250337 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029450 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" Cytosol "Nucleoplasm, Plasma membrane" "HPA029450: AB_10603118" "unprognostic (1.99e-1)" "unprognostic (2.08e-1)" "unprognostic (5.84e-2)" "prognostic favorable (6.09e-4)" "unprognostic (6.21e-2)" "unprognostic (5.55e-2)" "unprognostic (4.98e-3)" "unprognostic (4.25e-1)" "unprognostic (1.48e-1)" "unprognostic (4.22e-2)" "unprognostic (1.73e-2)" "unprognostic (3.17e-1)" "unprognostic (4.39e-3)" "unprognostic (1.76e-1)" "unprognostic (2.00e-1)" "unprognostic (2.68e-1)" "unprognostic (1.34e-1)" 15.2 24.9 17.6 11.8 17.5 15.0 16.2 16.3 20.5 14.0 19.5 20.0 17.3 13.8 20.8 22.8 18.1 13.0 19.0 16.5 16.8 26.5 43.2 14.3 17.6 17.9 17.5 14.8 30.9 22.7 19.8 9.2 16.9 20.3 13.5 7.9 20.0 10.9 14.4 17.3 17.8 9.9 17.4 21.2 24.2 27.7 18.6 20.5 19.3 8.2 14.5 17.8 14.8 16.5 14.1 18.8 15.7 13.2 40.0 40.0 17.9 17.8 23.6 14.3 14.7 21.2 31.0 8.3 24.4 32.0 23.4 14.5 18.5 30.0 7.8 20.0 19.8 17.7 15.4 19.1 34.9 17.6 20.1 40.1 48.1 20.8 57.4 29.8 17.9 18.7 23.1 21.5 26.8 27.1 19.4 38.0 14.5 25.7 10.3 18.1 17.5 24.9 32.2 16.1 12.3 14.6 5.8 25.5 39.0 11.2 27.4 36.4 13.7 20.6 14.0 16.4 17.4 25.9 12.1 19.5 22.9 18.4 18.3 1.6 7.0 5.3 4.9 3.8 5.5 7.2 6.0 9.2 6.8 6.0 6.1 7.9 4.1 14.5 3.1 5.8 7.3 8.7 17.6 17.5 16.3 20.5 16.5 16.8 17.9 17.5 16.9 17.4 18.6 16.5 11.8 6.4 5.6 3.6 22.4 9.8 18.1 32.6 24.5 7.9 31.8 31.8 9.5 24.3 19.7 7.3 16.7 24.0 23.6 27.6 68.4 40.3 87.2 21.4 13.3 14.0 25.8 36.0 2.2 58.5 25.0 15.8 17.3 12.9 8.2 17.9 12.5 43.7 28.4 13.5 2.7 38.7 16.2 27.1 17.6 70.3 15.2 17.8 21.4 0.0 38.4 22.1 44.3 4.0 6.8 33.3 44.3 13.5 27.6 18.6 58.9 80.2 19.6 19.1 0.0 11.9 19.2 43.1 9.6 28.2 11.2 12.9 22.1 33.6 34.2 20.8 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 376.2;lymphoid tissue: 113.3" "Cell type enhanced" "Detected in many" "B-cells: 229.3;dendritic cells: 267.7;granulocytes: 195.1;Langerhans cells: 201.3;Macrophages: 198.9;Plasma cells: 191.8;T-cells: 342.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 122.3;HMC-1: 118.9;Karpas-707: 111.6;U-698: 132.1" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 28.2 8.9 2.1 67.0 2.9 376.2 21.5 3.7 5.3 24.2 3.3 19.1 27.8 5.4 1.8 11.9 5.8 20.4 4.6 4.1 3.3 6.5 8.5 23.6 113.3 3.1 2.0 2.2 12.7 2.1 3.0 16.7 3.2 10.5 17.5 0.4 17.0 5.7 2.4 11.2 40.1 16.8 2.2 56.9 20.1 9.5 4.0 60.9 7.2 3.5 111.1 24.4 5.2 2.9 11.0 7.5 11.2 4.2 47.7 18.1 12.4 25.7 38.4 27.7 28.5 22.8 3.9 122.3 23.1 14.8 7.3 7.4 4.7 11.1 33.4 21.8 12.7 11.6 9.1 2.2 14.2 47.0 118.9 23.1 10.9 34.3 17.7 39.2 11.5 28.5 9.1 111.6 69.4 5.9 61.6 106.0 6.3 19.9 17.2 10.1 67.5 37.4 16.3 25.6 4.2 4.2 6.6 6.4 5.4 17.2 4.3 24.3 14.0 26.8 13.1 19.3 14.7 45.5 78.9 132.1 20.2 15.9 12.1 165.1 74.3 163.1 43.7 81.3 55.4 49.2 77.0 52.8 53.0 58.6 98.6 82.4 236.7 40.8 113.1 37.7 73.8 89.3 2.1 2.9 3.7 5.3 4.1 3.3 3.1 2.0 3.2 2.2 4.0 2.9 23.3 89.8 74.0 48.3 229.3 59.9 27.1 15.1 10.8 0.9 28.9 15.2 2.6 12.8 42.5 11.0 0.0 7.9 267.7 54.0 3.9 6.6 6.8 15.3 14.1 11.3 3.0 68.8 3.4 2.8 24.0 27.2 38.2 26.5 195.1 47.4 5.3 2.4 26.1 0.0 3.1 13.9 18.3 151.1 201.3 3.6 5.6 198.9 58.7 11.2 158.0 0.6 118.4 17.6 0.7 10.9 41.6 4.5 191.8 34.3 80.7 2.5 26.9 0.3 6.6 49.7 19.7 41.1 26.3 16.4 63.4 5.1 342.5 22.6 13.2 53.8 STOM "BND7, EPB7, EPB72" ENSG00000148175 Stomatin P27105 9 121338987-121370304 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 454.6;Erythroid cells: 535.1;Hepatocytes: 371.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 591.3;hTCEpi: 497.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010961, HPA011419" Approved Enhanced "Vesicles,Plasma membrane,Cytosol" NA NA 16000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Vesicles, Cytosol" "HPA010961: AB_1080111, HPA011419: AB_1080109" "unprognostic (1.11e-1)" "unprognostic (2.15e-2)" "unprognostic (5.27e-2)" "unprognostic (7.93e-2)" "unprognostic (5.68e-3)" "unprognostic (1.65e-2)" "unprognostic (9.20e-3)" "unprognostic (7.86e-2)" "unprognostic (1.76e-1)" "unprognostic (3.59e-2)" "unprognostic (3.32e-1)" "unprognostic (1.26e-1)" "unprognostic (5.23e-2)" "unprognostic (9.15e-3)" "unprognostic (2.27e-2)" "unprognostic (7.82e-2)" "unprognostic (2.99e-2)" 339.0 117.3 100.4 101.0 108.1 358.2 243.8 94.7 103.9 129.3 74.8 226.0 46.1 139.9 72.2 87.8 141.7 153.3 219.7 90.5 113.1 123.9 355.4 290.7 67.7 120.7 115.1 81.3 38.9 45.3 49.8 272.7 108.9 111.6 58.4 15.0 95.5 93.4 102.6 118.3 114.1 155.9 105.2 121.6 139.3 24.7 111.0 33.8 112.9 106.2 46.4 182.4 129.6 108.7 8.4 55.0 4.8 26.0 591.3 170.3 0.4 138.6 149.3 40.7 64.5 7.6 10.8 66.5 34.3 186.6 23.9 14.7 31.7 133.0 79.3 41.7 12.0 144.7 108.8 23.1 299.0 61.4 32.4 272.2 497.3 60.9 88.0 11.7 152.5 21.0 33.3 88.2 96.8 45.2 2.2 47.0 64.4 3.5 16.6 8.7 0.2 147.7 34.7 1.7 5.9 0.5 114.5 107.8 62.1 44.9 36.6 47.4 172.8 92.0 28.1 91.3 13.6 36.5 44.9 4.4 35.1 58.1 51.0 21.4 35.5 4.1 168.9 55.8 165.7 5.9 84.2 153.3 35.8 4.2 15.0 81.1 20.8 147.1 41.0 6.1 8.7 128.8 100.4 108.1 94.7 103.9 90.5 113.1 120.7 115.1 108.9 105.2 111.0 108.7 454.6 160.3 96.6 30.0 13.2 105.5 251.8 107.0 62.0 5.0 135.8 72.3 36.7 121.5 159.0 35.0 6.2 121.9 72.1 26.3 3.9 56.6 3.6 97.0 75.4 313.6 0.0 535.1 3.2 22.0 54.7 140.3 17.9 11.7 36.1 76.0 282.7 371.2 92.1 3.3 4.8 1.1 54.9 226.3 92.3 9.0 66.5 105.9 88.9 70.3 37.9 8.6 127.7 6.6 4.5 39.1 18.3 103.0 16.9 90.2 33.8 92.8 216.0 5.0 138.1 73.2 188.1 40.8 13.7 48.4 119.1 172.8 98.8 81.8 2.2 200.0 STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "CAB015944: , HPA062016: AB_2684659" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (5.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.74e-2)" "unprognostic (5.26e-1)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" 63.6 93.3 45.4 39.1 46.2 66.7 62.0 47.5 49.0 58.4 61.3 75.3 55.6 64.2 49.4 84.7 57.3 33.2 123.4 46.2 46.6 75.4 99.2 43.7 46.6 44.7 45.9 59.4 69.5 71.9 42.3 46.2 45.3 49.0 67.2 23.5 59.3 48.4 171.2 71.0 61.2 54.0 45.9 53.1 75.8 42.8 48.2 55.1 48.6 111.7 59.5 64.5 56.5 45.4 219.6 248.1 130.3 195.7 93.3 111.1 139.5 105.9 153.5 292.6 212.5 283.2 99.6 183.2 72.9 135.2 210.6 91.4 201.3 235.8 193.7 158.1 185.0 112.7 202.6 269.7 272.1 215.8 124.0 141.9 181.1 238.6 283.2 92.2 193.8 183.6 186.5 109.1 144.8 176.0 193.5 377.6 205.3 162.4 155.2 166.6 110.3 197.0 159.5 128.9 120.4 146.3 60.0 158.0 141.7 92.5 109.7 139.1 106.2 99.7 141.1 84.4 190.4 76.1 140.3 173.8 132.7 134.3 137.1 67.8 73.0 42.5 64.7 65.8 77.8 91.4 73.1 74.1 98.0 87.0 69.2 63.8 12.9 98.1 49.3 121.8 115.5 114.4 45.4 46.2 47.5 49.0 46.2 46.6 44.7 45.9 45.3 45.9 48.2 45.4 63.9 41.7 33.1 6.5 66.8 96.4 123.8 172.9 83.6 36.6 104.5 118.7 83.4 108.7 92.5 49.7 8.4 233.6 48.3 116.1 250.5 144.3 77.2 72.7 76.3 66.4 98.8 106.2 7.8 153.4 245.2 74.9 66.3 47.3 84.3 111.3 61.4 111.3 132.7 18.5 8.1 145.9 73.2 41.0 68.3 22.9 75.2 47.9 99.6 5.6 84.5 83.9 56.7 2.5 8.8 137.2 117.5 69.6 126.1 177.6 197.7 290.1 85.8 37.1 52.6 66.5 95.6 73.1 110.0 119.2 114.5 166.4 51.2 153.2 222.2 148.7 STOML3 "Epb7.2l, SRO" ENSG00000133115 "Stomatin like 3" Q8TAV4 13 38965925-38990859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "fallopian tube: 34.9" "Group enriched" "Detected in some" 19 "Endometrial ciliated cells: 75.5;Respiratory ciliated cells: 109.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 2.4;lung cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 40 "AF22: 17.5" "Region enriched" "Detected in many" 6 "olfactory bulb: 23.6" "HPA012892, HPA071011" Enhanced Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA012892: AB_1857610, HPA071011: AB_2732169" "unprognostic (2.64e-1)" "unprognostic (1.91e-2)" "prognostic favorable (1.49e-4)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "unprognostic (4.24e-2)" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.14e-1)" "unprognostic (1.07e-2)" "unprognostic (1.35e-2)" "unprognostic (3.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.22e-1)" 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.5 0.0 0.7 1.3 0.1 0.0 0.6 0.0 0.0 34.9 0.0 0.0 1.1 1.8 0.0 0.0 2.1 0.0 4.7 5.1 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.5 0.0 1.1 1.8 4.7 5.1 5.0 2.0 0.9 1.3 0.0 0.0 1.5 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.4 0.1 0.0 4.8 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.4 75.5 0.4 0.3 0.0 0.0 0.1 0.0 1.1 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 1.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 109.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 119.9" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 191.1;Glandular and luminal cells: 249.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003019: AB_1857622" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.84e-4)" "prognostic favorable (6.33e-8)" "unprognostic (4.21e-1)" "unprognostic (6.77e-2)" "unprognostic (6.17e-3)" "unprognostic (2.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "prognostic favorable (7.03e-4)" "unprognostic (1.92e-2)" "unprognostic (1.55e-1)" "unprognostic (7.44e-2)" "prognostic favorable (4.69e-4)" 10.6 16.0 8.4 10.9 9.4 12.0 10.9 8.9 10.4 119.9 14.5 12.8 18.1 53.9 8.2 10.7 48.6 14.0 13.0 7.9 9.9 29.2 15.7 10.8 13.2 9.4 8.9 11.3 22.5 16.9 14.6 12.8 10.1 10.6 13.4 8.3 12.1 8.9 16.5 12.0 15.6 15.7 8.2 10.6 18.5 30.5 10.2 9.4 11.3 9.9 12.4 11.0 11.8 9.3 26.6 16.7 19.3 20.0 16.2 23.7 26.1 30.1 26.9 27.6 22.8 35.5 37.3 35.1 69.7 27.1 24.9 13.9 34.6 17.2 27.0 15.1 18.6 22.0 22.3 43.4 24.2 38.6 17.8 22.2 14.7 23.4 16.9 15.4 23.5 27.5 21.7 30.0 19.9 14.0 35.6 27.2 26.0 21.3 36.1 31.4 14.6 28.2 28.2 15.6 24.7 22.0 22.2 14.7 26.4 16.5 21.6 18.3 27.2 16.7 18.4 15.4 32.1 21.6 35.4 40.1 20.4 29.3 21.0 10.6 15.6 10.8 15.1 16.0 18.2 16.7 14.0 13.7 23.8 14.4 11.7 13.4 3.1 16.9 20.6 37.6 14.3 14.0 8.4 9.4 8.9 10.4 7.9 9.9 9.4 8.9 10.1 8.2 10.2 9.3 17.5 32.1 9.0 52.5 15.8 7.9 8.3 20.3 9.6 39.3 14.4 11.6 20.4 18.6 25.3 20.2 20.9 31.0 27.9 33.8 70.5 32.5 80.6 191.1 38.4 14.8 4.9 15.6 40.2 27.9 19.0 18.5 23.9 249.4 8.2 21.6 6.8 10.8 28.1 10.1 48.0 22.8 32.6 13.7 12.4 76.5 14.0 21.3 14.2 48.7 26.5 25.8 16.5 37.7 56.4 36.5 28.8 14.7 20.4 15.7 32.8 25.2 34.5 17.7 6.6 13.1 18.1 94.9 35.7 13.1 9.7 31.7 18.9 27.2 20.0 13.9 STX4 "p35-2, STX4A" ENSG00000103496 "Syntaxin 4" Q12846 16 31032889-31042975 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001330 Approved Enhanced "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA001330: AB_1080167" "unprognostic (2.31e-3)" "prognostic favorable (3.65e-4)" "unprognostic (3.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.74e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "unprognostic (5.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.01e-2)" "unprognostic (3.12e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.88e-9)" "unprognostic (6.90e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.26e-2)" 38.3 44.0 33.1 34.2 36.2 22.3 33.9 37.4 36.4 36.3 32.3 37.5 38.3 31.4 24.4 35.8 29.8 27.7 39.8 33.2 37.8 33.5 35.8 36.2 31.1 38.0 36.6 30.4 27.7 38.4 23.2 32.3 37.7 29.9 28.6 8.5 29.9 26.5 45.8 44.3 35.9 31.6 36.1 43.7 32.4 14.9 36.2 28.4 29.5 33.8 37.1 38.1 32.6 39.0 51.9 70.6 16.0 36.1 51.1 52.1 33.8 47.7 79.2 47.5 48.7 22.1 53.2 35.4 58.9 80.8 54.4 36.6 15.2 52.6 45.6 60.3 43.8 25.3 48.7 59.7 58.3 29.2 80.1 50.2 36.1 82.1 61.1 58.5 64.3 22.3 29.9 38.6 84.9 80.3 28.0 44.8 33.1 36.9 36.7 24.0 47.1 46.1 45.9 38.7 13.1 24.6 40.6 41.1 17.4 20.7 33.7 38.7 74.4 48.3 21.8 55.8 26.6 41.2 37.0 14.6 73.3 46.4 29.7 21.3 21.7 27.3 17.6 23.8 15.4 12.7 14.7 17.9 18.8 17.5 11.0 14.2 23.0 24.6 21.9 11.1 9.0 11.2 33.1 36.2 37.4 36.4 33.2 37.8 38.0 36.6 37.7 36.1 36.2 39.0 34.9 44.8 22.7 7.8 32.6 65.1 34.6 56.3 31.9 7.4 22.3 20.6 23.6 48.6 35.2 22.0 12.5 31.1 35.9 69.7 29.4 60.6 12.9 22.1 26.6 46.0 25.7 11.1 4.8 67.7 35.7 51.7 43.3 29.0 60.3 42.1 33.9 20.0 89.5 5.0 3.6 39.5 38.7 49.6 149.9 15.7 38.5 83.2 30.2 2.8 51.7 24.1 42.2 3.0 16.0 73.4 58.5 35.3 23.0 61.6 77.7 50.8 31.3 6.9 39.5 40.6 36.4 9.4 6.7 27.0 65.1 33.1 35.4 39.0 47.9 36.2 STXBP4 "MGC50337, Synip" ENSG00000166263 "Syntaxin binding protein 4" Q6ZWJ1 17 54968727-55173632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Cone photoreceptor cells: 41.7;Oligodendrocyte precursor cells: 84.4;Oligodendrocytes: 39.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007760, HPA022138, HPA022888, HPA024227" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB007760: AB_562350, HPA022138: AB_1857628, HPA022888: AB_1857629, HPA024227: AB_1857630" "unprognostic (5.89e-2)" "unprognostic (2.50e-2)" "unprognostic (1.30e-3)" "unprognostic (9.27e-2)" "unprognostic (1.03e-3)" "unprognostic (1.48e-1)" "unprognostic (5.00e-5)" "unprognostic (4.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-2)" "unprognostic (3.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" 1.4 2.0 2.3 1.7 2.3 1.4 1.8 2.2 1.7 2.2 7.8 1.7 2.5 2.8 1.7 1.9 2.8 2.6 1.8 1.5 3.1 4.3 0.9 2.1 1.2 3.2 3.9 2.9 1.5 6.0 2.0 1.8 2.8 3.0 1.7 4.5 1.4 3.5 1.1 1.0 1.4 2.7 3.0 1.1 1.6 2.1 3.2 1.8 3.1 1.0 1.2 1.9 1.3 3.7 5.0 7.3 6.6 5.9 5.5 5.4 2.7 3.8 3.6 4.8 4.7 4.3 2.6 3.4 7.9 3.8 4.2 2.9 8.6 3.8 8.9 5.1 4.9 4.4 4.8 8.9 2.3 2.8 1.3 6.1 1.1 7.0 1.6 2.2 4.9 2.9 7.2 2.6 5.8 2.2 9.3 1.8 4.8 4.2 5.2 3.9 7.7 2.0 8.6 3.0 6.3 4.8 5.8 0.9 3.2 3.5 8.4 1.9 3.8 6.8 5.2 4.2 4.0 2.3 2.3 5.8 4.4 3.6 4.1 1.7 0.4 0.0 0.9 0.3 1.0 0.7 0.8 0.6 0.5 1.1 0.7 0.9 0.1 2.2 0.5 1.1 0.8 0.3 2.3 2.3 2.2 1.7 1.5 3.1 3.2 3.9 2.8 3.0 3.2 3.7 6.6 0.0 9.1 39.5 3.9 0.9 2.4 3.3 4.6 5.6 4.4 3.3 9.6 2.8 5.4 9.2 41.7 1.6 2.1 2.0 9.8 6.0 6.7 16.6 14.4 4.3 6.0 5.2 29.0 2.7 1.9 7.5 6.1 5.8 7.6 6.1 6.1 5.1 2.3 8.4 25.5 1.4 0.0 2.4 1.4 5.3 17.7 2.4 7.2 20.6 2.1 5.9 1.0 84.4 39.3 3.3 2.1 11.7 1.6 2.2 4.9 7.2 17.4 21.6 32.9 8.8 11.4 11.1 7.3 2.8 3.0 0.3 4.8 5.1 3.1 1.2 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.1;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Excitatory neurons: 20.6;Gastric mucus-secreting cells: 15.3;Paneth cells: 12.6;Proximal enterocytes: 10.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 28.7;HDLM-2: 17.5;HMC-1: 18.3;HUVEC TERT2: 25.5;TIME: 23.8" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.4 0.3 1.2 1.8 3.0 1.1 3.9 0.0 5.2 1.9 0.0 15.9 2.4 0.5 1.2 7.3 2.2 3.5 0.1 3.6 0.0 0.6 0.3 1.3 1.4 0.0 0.0 0.3 0.3 0.0 2.4 0.7 0.0 11.6 17.1 0.9 6.7 0.9 0.1 2.8 11.2 0.6 0.0 0.9 17.5 0.2 0.0 0.2 0.4 0.0 2.5 5.1 3.3 0.3 4.8 0.2 0.0 0.6 0.0 0.0 1.3 7.3 0.7 3.5 3.4 2.6 28.7 0.3 4.7 1.8 4.5 1.4 1.6 8.0 7.4 17.5 0.4 1.0 2.4 0.2 0.0 2.2 18.3 0.4 0.4 5.1 0.3 0.5 25.5 0.2 0.3 0.3 8.1 3.1 0.2 1.3 4.2 11.8 2.0 0.1 2.0 0.3 2.5 14.6 0.9 0.1 4.5 4.9 0.0 6.7 3.5 0.6 23.8 1.0 3.8 0.5 0.8 0.0 1.0 0.2 3.5 0.2 5.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.1 12.5 0.0 0.0 0.0 0.3 1.2 3.0 0.0 5.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.2 0.0 0.0 0.3 0.8 3.1 1.2 0.6 3.3 2.0 0.7 1.5 3.3 0.0 0.0 0.1 1.8 19.6 0.0 0.5 0.2 7.3 0.5 0.4 4.2 0.8 20.6 0.2 0.6 0.2 15.3 4.5 1.3 6.3 0.0 0.0 0.0 0.0 1.6 8.9 2.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 6.2 0.0 0.5 5.9 12.6 0.0 0.9 4.7 10.6 0.0 8.8 0.4 0.0 1.2 0.2 0.2 0.8 3.1 1.0 0.3 1.9 0.0 6.9 5.5 SUCLG1 ENSG00000163541 "Succinate-CoA ligase GDP/ADP-forming subunit alpha" P53597 2 84423528-84460045 "Citric acid cycle related proteins, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 554.0" "Cell type enhanced" "Detected in all" "Distal tubular cells: 935.2;Proximal enterocytes: 647.5;Proximal tubular cells: 2949.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036683, HPA036684" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Intracellular and membrane" NA NA 350000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Mitochondria "Plasma membrane, Cytosol" "HPA036683: AB_10671708, HPA036684: AB_2675248" "unprognostic (6.84e-3)" "unprognostic (7.16e-3)" "unprognostic (2.58e-3)" "prognostic unfavorable (5.23e-4)" "unprognostic (1.02e-1)" "unprognostic (2.11e-1)" "unprognostic (3.63e-2)" "unprognostic (3.49e-2)" "unprognostic (1.02e-1)" "unprognostic (2.00e-1)" "unprognostic (2.36e-2)" "unprognostic (9.24e-2)" "prognostic favorable (2.21e-8)" "unprognostic (4.94e-2)" "unprognostic (2.08e-1)" "unprognostic (2.81e-2)" "unprognostic (1.23e-1)" 118.7 73.3 70.6 43.1 73.2 48.2 80.0 76.2 92.5 49.9 91.1 156.9 231.1 42.4 78.8 86.9 54.6 41.9 258.1 71.1 74.5 554.0 193.0 41.6 47.8 71.7 70.2 45.7 93.6 244.2 46.8 48.8 72.9 54.3 165.9 38.4 120.6 66.6 274.1 55.4 195.4 63.5 73.8 39.6 81.1 36.9 73.3 61.7 97.6 368.1 63.1 66.4 58.5 76.9 90.2 94.9 73.8 91.1 137.8 91.2 127.7 98.4 85.2 126.0 91.2 224.5 72.0 122.4 67.0 119.8 100.2 126.8 156.7 118.4 149.8 119.3 141.4 105.9 75.4 129.2 116.0 110.6 82.7 109.1 95.6 106.3 143.7 76.7 115.1 97.9 110.1 98.1 117.5 137.4 158.2 101.1 39.4 334.1 170.0 98.3 172.6 134.5 172.2 106.4 89.8 49.3 78.9 163.7 162.3 69.0 99.8 85.4 93.1 96.6 94.6 119.9 124.9 84.2 131.0 107.8 113.9 150.4 88.0 101.6 91.0 80.8 79.0 110.2 88.5 70.2 72.0 88.4 115.4 55.4 79.1 84.3 49.7 102.3 114.3 63.2 107.7 142.7 70.6 73.2 76.2 92.5 71.1 74.5 71.7 70.2 72.9 73.8 73.3 76.9 52.7 64.1 96.5 32.7 61.0 35.4 108.9 129.6 44.3 33.3 105.0 109.1 408.6 131.5 115.2 141.6 22.9 232.3 49.9 218.1 935.2 131.8 49.2 67.1 56.9 57.0 106.3 68.4 45.8 113.2 129.3 69.8 79.5 80.8 91.3 46.0 57.5 210.0 131.7 45.4 43.5 202.1 105.8 71.3 46.0 35.9 54.7 82.2 119.2 16.9 89.8 68.2 58.7 28.1 46.2 67.1 215.4 74.1 57.1 64.2 647.5 2949.2 83.7 36.1 52.6 61.1 98.3 138.9 54.4 111.3 41.3 188.4 64.4 90.7 388.7 111.0 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 278.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 402.3;Proximal tubular cells: 354.4;Undifferentiated cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 300000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 66.7 44.9 16.1 36.7 17.9 18.6 48.7 17.1 19.6 42.1 22.4 169.7 136.6 32.6 32.2 50.5 39.1 48.4 85.5 14.2 17.6 147.3 278.0 34.0 39.3 19.0 17.3 39.0 47.8 34.6 10.2 28.1 19.5 49.3 146.1 7.3 46.8 42.3 154.0 26.1 132.2 40.0 17.7 44.8 110.6 10.4 18.1 24.7 49.3 130.6 35.5 39.3 24.0 18.8 43.8 37.4 36.3 44.6 59.7 102.5 44.2 51.3 74.4 58.9 65.4 41.7 95.1 55.7 16.3 72.5 38.8 22.0 28.5 70.8 75.9 23.8 19.5 50.5 31.2 65.5 76.8 67.2 33.9 77.3 60.3 46.2 105.2 73.0 63.6 41.8 39.1 49.5 129.9 30.6 25.5 21.2 34.1 199.2 23.0 17.6 56.1 83.8 100.0 66.9 7.1 24.5 81.5 92.7 68.8 24.3 71.6 42.5 55.9 58.2 38.2 64.5 61.8 33.4 52.2 39.0 85.5 51.6 70.0 17.3 36.3 13.0 30.8 44.3 37.6 45.5 44.6 39.5 24.6 42.5 68.4 53.1 1.6 68.0 37.4 9.8 45.4 48.5 16.1 17.9 17.1 19.6 14.2 17.6 19.0 17.3 19.5 17.7 18.1 18.8 40.2 35.3 50.8 66.6 48.5 37.1 44.7 38.9 21.1 2.9 54.1 29.1 172.0 84.4 51.7 80.9 8.4 55.4 31.7 223.5 244.6 85.1 3.2 49.6 43.4 40.1 58.2 17.2 6.2 80.9 44.9 47.5 90.7 46.8 30.4 31.4 45.0 402.3 56.5 5.0 5.3 212.1 40.7 68.6 49.2 5.4 41.3 36.3 42.7 90.9 35.5 29.2 36.0 72.4 60.0 59.2 164.0 47.4 30.3 41.2 222.2 354.4 58.7 4.5 32.9 41.6 50.5 1.6 6.3 55.6 49.3 38.0 48.6 78.5 306.6 50.9 SUGT1 SGT1 ENSG00000165416 "SGT1 homolog, MIS12 kinetochore complex assembly cochaperone" Q9Y2Z0 13 52652709-52700909 "Plasma proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015942, HPA043949" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA 17000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB015942: , HPA043949: AB_2678745" "unprognostic (3.66e-2)" "unprognostic (3.98e-2)" "unprognostic (3.57e-1)" "unprognostic (1.22e-1)" "unprognostic (3.77e-2)" "prognostic unfavorable (8.69e-4)" "unprognostic (2.24e-1)" "unprognostic (2.96e-1)" "unprognostic (3.76e-1)" "unprognostic (1.96e-3)" "unprognostic (9.51e-2)" "unprognostic (1.12e-1)" "unprognostic (6.83e-2)" "unprognostic (2.82e-3)" "unprognostic (9.05e-2)" "unprognostic (2.93e-2)" "unprognostic (1.56e-1)" 27.4 31.4 33.4 25.5 38.1 32.0 23.6 38.6 55.6 23.0 33.1 25.5 27.3 19.6 20.3 30.1 19.4 19.6 37.0 34.8 37.0 31.7 36.5 22.5 27.4 34.8 34.8 21.5 30.6 19.8 26.9 25.9 36.9 19.6 26.9 22.2 25.2 16.3 29.6 24.5 26.8 22.1 35.3 23.2 26.8 34.5 36.4 29.8 21.1 28.1 29.9 27.3 24.3 48.1 47.0 50.2 72.9 55.6 70.4 57.0 69.8 100.8 66.3 61.7 49.0 110.3 114.7 102.4 27.9 62.8 89.5 79.0 90.6 57.9 90.0 85.3 37.7 95.1 65.8 84.4 51.1 74.8 68.7 40.0 51.7 63.9 48.2 79.0 105.0 64.8 90.5 32.7 95.7 33.4 70.3 136.6 85.3 183.9 47.8 79.6 42.4 44.4 108.0 51.7 24.1 30.7 52.1 42.2 49.8 82.6 43.5 70.3 76.1 51.3 59.9 59.6 87.6 25.7 38.9 91.5 30.8 59.2 75.5 63.6 29.0 49.0 24.3 34.5 23.9 30.9 31.4 33.2 32.9 30.3 23.8 26.6 4.1 33.2 34.1 41.0 46.0 25.2 33.4 38.1 38.6 55.6 34.8 37.0 34.8 34.8 36.9 35.3 36.4 48.1 82.1 38.5 36.0 22.2 46.1 39.8 65.4 68.2 38.1 52.6 40.6 55.8 126.2 32.9 51.8 51.5 25.0 67.0 78.3 52.3 78.2 88.3 185.6 112.0 79.0 65.9 34.1 65.2 19.9 89.0 143.0 60.9 50.0 75.1 36.8 49.7 43.5 38.3 97.8 50.5 23.0 58.2 54.9 44.5 43.9 95.7 58.7 54.3 48.0 13.1 123.7 91.8 58.7 21.1 47.6 85.2 55.0 59.8 58.3 44.1 74.3 100.9 67.8 56.6 26.3 72.4 92.1 146.7 101.0 45.7 43.2 74.4 61.1 56.1 55.5 52.3 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SUPT6H "KIAA0162, SPT6H" ENSG00000109111 "SPT6 homolog, histone chaperone and transcription elongation factor" Q7KZ85 17 28662198-28702679 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, mRNA processing, mRNA splicing, mRNA transport, Transcription, Transcription regulation, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012416, HPA036382" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB012416: , HPA036382: AB_2675094" "unprognostic (8.18e-2)" "unprognostic (2.27e-1)" "unprognostic (2.72e-1)" "unprognostic (1.75e-2)" "unprognostic (1.06e-1)" "unprognostic (8.23e-2)" "prognostic unfavorable (3.68e-5)" "unprognostic (1.02e-1)" "unprognostic (2.18e-2)" "unprognostic (9.97e-3)" "unprognostic (1.29e-2)" "unprognostic (1.17e-1)" "prognostic favorable (4.36e-5)" "unprognostic (4.75e-2)" "unprognostic (1.05e-1)" "unprognostic (4.17e-2)" "unprognostic (1.06e-2)" 31.2 33.5 24.6 25.4 25.8 65.3 28.3 25.0 26.8 27.0 26.8 36.6 20.0 30.6 26.8 26.5 26.6 24.7 28.8 24.0 29.0 25.6 35.8 28.9 28.4 24.0 25.2 31.2 31.4 30.8 34.3 27.8 24.3 28.7 20.9 29.2 29.1 25.6 54.5 39.2 32.2 27.3 21.6 34.4 31.3 21.4 28.7 34.0 28.9 32.6 30.3 32.1 25.6 25.6 49.4 101.3 49.8 57.1 59.1 39.3 38.2 66.2 70.3 76.3 67.8 94.7 21.5 52.1 33.6 66.5 58.7 57.5 73.6 48.1 78.4 97.6 65.4 72.9 83.2 59.4 49.4 77.2 77.9 54.6 28.4 81.2 53.6 50.3 50.8 50.3 72.9 59.7 55.1 59.1 76.9 33.4 38.7 43.2 32.4 38.7 91.2 42.7 37.6 95.9 37.8 49.9 77.6 120.5 41.6 67.9 74.2 54.2 80.6 59.8 49.4 57.5 85.3 75.4 62.2 74.4 67.5 34.4 50.5 14.7 4.5 4.4 3.7 2.9 3.9 4.5 3.1 4.1 3.7 4.5 3.1 2.8 6.8 4.3 5.0 6.2 3.1 3.1 24.6 25.8 25.0 26.8 24.0 29.0 24.0 25.2 24.3 21.6 28.7 25.6 33.9 38.5 51.0 24.2 36.5 22.4 19.2 16.8 43.3 29.5 27.4 26.0 51.6 22.8 28.4 20.2 56.3 24.4 38.4 29.5 5.9 22.1 5.4 31.0 45.3 32.6 31.0 33.0 21.6 21.3 21.3 32.7 46.4 49.1 50.5 36.6 22.9 33.9 23.7 30.3 19.7 23.1 8.2 23.0 22.4 17.8 25.7 41.8 8.8 16.9 29.9 22.0 30.9 17.6 19.4 31.9 18.7 26.7 55.7 20.0 23.4 10.5 25.7 44.4 32.9 32.4 32.0 19.8 19.1 40.1 24.3 49.8 38.3 42.0 22.9 25.7 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SVIL ENSG00000197321 Supervillin O95425 10 29457338-29736959 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 808.1;tongue: 581.5" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 204.9;Cardiomyocytes: 469.6;Peritubular cells: 260.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 259.3" "Lineage enriched" "Detected in all" 9 "granulocytes: 259.3" "Cell line enhanced" "Detected in many" "HaCaT: 146.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010878, HPA020095, HPA020138" Approved Supported "Plasma membrane,Actin filaments,Cytosol" NA NA 210000 "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "Actin filaments, Cytosol" "CAB010878: AB_476685, HPA020095: AB_1857680, HPA020138: AB_1857681" "unprognostic (1.11e-1)" "unprognostic (2.94e-1)" "unprognostic (8.06e-2)" "unprognostic (1.15e-2)" "unprognostic (3.47e-3)" "unprognostic (2.26e-2)" "unprognostic (4.12e-1)" "unprognostic (1.49e-1)" "unprognostic (4.28e-1)" "unprognostic (3.42e-3)" "unprognostic (1.55e-1)" "unprognostic (9.20e-2)" "unprognostic (2.38e-3)" "unprognostic (7.11e-3)" "unprognostic (1.51e-1)" "unprognostic (2.50e-1)" "prognostic unfavorable (5.70e-5)" 26.4 13.4 3.7 22.7 3.9 37.2 22.6 1.3 8.9 45.8 2.5 314.5 14.8 116.2 24.1 92.1 55.5 52.0 165.0 2.2 2.7 15.4 10.4 22.9 12.6 7.0 4.1 83.3 18.5 31.8 8.5 17.9 4.4 70.3 37.1 10.3 40.6 100.0 808.1 26.9 60.1 107.0 4.4 7.6 77.6 11.7 4.9 19.1 35.0 581.5 10.8 173.2 40.3 5.2 71.4 27.9 12.4 5.4 32.1 84.4 22.1 12.6 24.1 4.3 4.7 34.4 63.1 2.4 43.0 4.9 31.9 146.8 8.6 25.6 5.2 1.4 17.6 0.1 33.6 19.9 21.4 8.0 1.5 72.7 24.5 44.2 19.1 71.9 69.6 14.7 0.1 0.4 6.7 19.9 7.7 4.0 7.0 27.8 15.1 15.5 32.1 0.9 40.2 20.1 18.1 14.1 12.3 1.4 34.3 39.8 12.9 7.9 46.3 21.9 23.4 94.4 34.4 0.6 0.8 0.3 64.5 14.0 65.4 43.4 12.1 58.2 11.1 14.0 10.9 0.6 11.2 7.6 7.3 1.0 17.1 10.9 259.3 14.6 29.6 3.0 4.3 3.7 3.7 3.9 1.3 8.9 2.2 2.7 7.0 4.1 4.4 4.4 4.9 5.2 31.3 48.1 30.5 2.3 3.7 70.2 108.0 41.1 204.9 11.7 36.6 67.1 469.6 18.6 53.5 38.6 25.0 29.7 11.3 39.7 7.9 94.1 4.0 26.3 65.8 61.1 23.9 1.7 8.3 42.3 18.5 68.1 7.7 43.6 10.1 35.7 32.2 11.8 10.4 5.0 43.9 31.3 28.5 7.5 45.7 6.8 109.6 25.3 28.4 146.1 16.7 30.6 13.4 28.1 6.6 63.4 40.2 260.7 3.3 131.8 18.4 10.8 42.2 15.0 46.0 90.6 92.9 6.5 11.1 103.8 60.0 24.8 14.6 27.9 39.2 98.3 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYCP2 SCP2 ENSG00000196074 "Synaptonemal complex protein 2" Q9BX26 20 59863564-59933655 "Disease related genes, Predicted intracellular proteins" "Cell cycle, Cell division, Meiosis" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 43.2" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 468.5" "Group enriched" "Detected in many" 6 "breast cancer: 6.7;cervical cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 25.9;JURKAT: 47.2;MOLT-4: 54.4;SiHa: 92.2;T-47d: 82.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA062401, HPA065613" Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Nucleoplasm "Plasma membrane, Cytosol" "HPA062401: AB_2684752, HPA065613: AB_2685519" "unprognostic (8.10e-3)" "unprognostic (8.28e-3)" "unprognostic (1.62e-1)" "unprognostic (2.48e-2)" "unprognostic (1.57e-1)" "unprognostic (1.19e-3)" "unprognostic (2.50e-2)" "unprognostic (2.18e-1)" "unprognostic (4.11e-2)" "unprognostic (1.44e-1)" "unprognostic (3.74e-1)" "unprognostic (7.02e-3)" "unprognostic (4.84e-3)" "unprognostic (8.48e-2)" "unprognostic (2.46e-1)" "unprognostic (7.87e-3)" "unprognostic (1.21e-1)" 3.2 0.8 2.2 1.4 2.8 2.4 13.9 9.7 4.9 2.4 0.0 1.3 1.6 1.6 1.2 0.9 1.3 2.4 2.5 2.2 1.1 4.3 1.1 2.2 2.6 1.8 1.8 0.7 6.6 0.7 1.9 3.9 2.2 3.8 1.1 1.5 4.4 1.0 1.3 2.7 2.4 0.7 1.4 3.1 6.1 43.2 2.5 1.3 2.4 1.0 1.7 1.8 1.5 4.1 0.3 1.3 0.2 1.4 0.6 0.8 1.4 4.1 1.1 1.8 0.2 25.9 2.6 0.1 4.0 1.8 0.8 0.6 0.5 0.1 1.0 8.5 0.6 0.2 6.1 0.4 0.2 0.4 19.0 0.4 0.4 0.4 0.0 0.9 0.0 47.2 0.2 0.0 0.9 12.5 54.4 2.9 0.4 1.5 0.3 0.0 0.1 0.2 2.1 6.1 0.2 4.5 92.2 13.3 3.3 1.6 82.6 4.7 0.5 0.1 2.8 11.2 0.0 0.0 0.0 0.0 0.0 1.7 5.2 0.7 0.1 0.7 0.8 0.0 0.8 0.2 0.4 0.5 0.0 0.2 0.2 0.4 0.7 0.0 0.0 0.0 0.3 0.2 2.2 2.8 9.7 4.9 2.2 1.1 1.8 1.8 2.2 1.4 2.5 4.1 11.5 0.0 1.1 24.5 1.4 1.0 1.1 1.0 0.0 1.9 12.7 9.4 3.6 2.8 6.3 1.8 2.1 0.8 3.0 0.1 1.9 0.9 82.3 0.4 5.0 6.5 0.0 0.0 27.5 3.6 0.4 2.1 2.6 0.5 2.5 1.2 2.9 0.0 0.5 0.0 14.6 0.1 0.0 1.2 0.8 21.8 4.7 1.6 5.4 13.1 1.4 2.3 5.2 28.6 11.1 1.2 1.2 1.9 0.4 1.8 0.3 5.4 8.6 1.1 52.6 1.7 3.8 468.5 92.4 0.6 0.0 0.4 4.1 0.2 0.3 1.2 SYK ENSG00000165025 "Spleen associated tyrosine kinase" P43405 9 90801787-90898549 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Host-virus interaction, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 73.8;parathyroid gland: 87.6" "Cell type enhanced" "Detected in many" "B-cells: 91.3;Hofbauer cells: 73.1;Kupffer cells: 96.7;Macrophages: 95.2;Microglial cells: 114.3;monocytes: 92.5;Plasma cells: 83.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 13 "classical monocyte: 77.3;eosinophil: 83.5;intermediate monocyte: 64.0;memory B-cell: 74.5;myeloid DC: 85.1;naive B-cell: 58.4;neutrophil: 112.1;NK-cell: 30.0;non-classical monocyte: 60.2;plasmacytoid DC: 63.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 125.8;HEL: 72.8;HL-60: 101.6;HMC-1: 64.1;REH: 84.4;THP-1: 76.8;U-698: 58.8;U-937: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001384, CAB007773" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" No NA 290000 "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Vesicles "CAB007773: AB_562232, HPA001384: AB_1080144" "unprognostic (1.01e-1)" "unprognostic (5.45e-2)" "unprognostic (2.10e-1)" "unprognostic (2.69e-2)" "unprognostic (2.31e-1)" "unprognostic (7.92e-2)" "unprognostic (1.06e-1)" "unprognostic (1.34e-1)" "unprognostic (6.41e-2)" "unprognostic (1.78e-2)" "unprognostic (7.20e-2)" "unprognostic (9.93e-2)" "unprognostic (2.55e-3)" "unprognostic (8.77e-2)" "unprognostic (5.36e-3)" "unprognostic (3.41e-2)" "unprognostic (1.06e-2)" 7.4 4.6 4.1 42.5 4.1 50.9 6.8 4.5 4.9 7.7 4.2 20.1 30.8 4.1 16.1 17.5 17.0 12.9 2.9 3.8 5.0 11.2 4.5 20.6 61.8 7.1 5.8 1.7 9.1 87.6 2.4 12.0 7.0 3.8 20.5 0.7 8.4 4.2 1.0 9.9 36.3 9.3 6.6 40.3 19.1 6.9 7.1 49.7 25.6 2.4 73.8 17.5 8.3 9.8 22.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 14.3 125.8 3.5 0.0 4.2 19.1 2.7 10.2 0.0 0.0 17.0 72.8 0.0 0.0 0.0 101.6 64.1 0.0 14.0 0.0 1.4 0.0 0.0 15.5 2.0 9.9 0.0 15.4 0.1 44.4 0.7 47.0 0.0 84.4 0.1 34.6 2.6 18.6 6.4 5.7 0.1 8.7 0.1 0.3 7.9 76.8 0.2 0.0 0.4 0.1 0.1 0.2 0.0 58.8 0.0 70.3 0.0 5.3 77.3 83.5 0.3 64.0 0.3 74.5 0.2 0.2 85.1 58.4 0.2 0.1 112.1 30.0 60.2 63.2 0.1 44.6 4.1 4.1 4.5 4.9 3.8 5.0 7.1 5.8 7.0 6.6 7.1 9.8 0.5 12.8 20.2 0.0 91.3 3.4 3.7 8.7 12.0 1.4 6.3 2.8 1.6 14.3 12.8 14.7 0.0 1.3 70.4 16.5 15.6 15.0 7.1 10.7 1.0 2.1 10.3 37.9 0.4 12.5 2.6 2.1 22.4 12.6 43.6 0.0 3.3 1.0 73.1 0.0 0.7 24.4 0.0 96.7 28.8 6.2 0.6 95.2 12.4 114.3 92.5 0.0 62.8 1.5 0.5 18.2 25.1 0.0 83.1 2.5 31.4 0.4 10.4 0.2 6.6 0.7 2.3 0.8 0.7 30.4 5.7 1.4 8.3 0.0 31.1 8.0 SYMPK "SPK, SYM" ENSG00000125755 Symplekin Q92797 19 45815410-45863194 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, mRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 141.6;Late spermatids: 146.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041756, HPA042449" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane, Cytosol" "HPA041756: AB_10963544, HPA042449: AB_2678003" "unprognostic (1.24e-1)" "unprognostic (1.23e-1)" "unprognostic (1.21e-1)" "unprognostic (2.59e-1)" "unprognostic (1.59e-2)" "unprognostic (3.11e-2)" "unprognostic (2.33e-3)" "unprognostic (9.93e-2)" "unprognostic (9.78e-2)" "unprognostic (1.23e-1)" "unprognostic (9.16e-3)" "unprognostic (1.67e-2)" "unprognostic (1.44e-1)" "unprognostic (2.34e-1)" "unprognostic (1.29e-1)" "unprognostic (2.58e-1)" "unprognostic (6.38e-2)" 18.0 17.3 15.5 29.3 17.0 27.4 18.0 12.5 19.8 24.1 11.9 22.5 22.2 25.3 20.1 19.7 23.5 18.0 17.5 14.9 14.1 19.1 21.4 20.6 34.8 18.9 15.6 23.6 19.1 20.7 32.6 25.0 17.1 23.8 14.1 15.7 24.7 16.4 38.5 25.3 22.8 16.1 11.4 28.5 22.9 41.0 16.6 30.0 24.0 18.9 22.8 20.7 19.9 22.7 57.7 101.0 40.4 29.9 39.0 46.8 67.7 44.5 32.0 45.8 51.0 45.8 51.1 101.6 30.2 51.0 25.7 46.2 55.1 49.9 40.0 79.4 62.2 58.7 68.9 47.5 43.7 64.9 65.6 36.1 29.2 49.3 55.4 31.2 47.6 52.6 79.3 64.4 39.4 54.8 61.0 70.3 34.0 50.0 23.9 64.6 46.4 62.6 31.8 102.7 46.0 57.7 55.1 35.5 36.7 40.3 48.4 89.4 53.5 37.1 58.5 28.8 66.9 84.1 173.1 81.5 42.4 42.8 61.8 1.7 3.0 1.5 2.0 2.5 1.9 2.9 1.8 3.2 2.8 4.8 1.5 1.4 3.4 2.7 5.0 5.8 1.4 2.1 15.5 17.0 12.5 19.8 14.9 14.1 18.9 15.6 17.1 11.4 16.6 22.7 14.7 0.0 7.7 34.9 30.2 20.9 18.7 15.6 18.2 21.6 17.4 15.4 7.0 22.8 12.0 25.8 35.5 35.5 20.9 32.7 54.8 21.6 141.6 24.9 29.9 23.4 36.3 26.5 24.6 17.5 34.5 17.5 41.8 27.7 12.7 35.1 26.0 31.8 18.2 21.9 27.1 38.7 10.2 27.0 25.6 146.4 19.3 24.4 14.2 19.7 47.3 11.3 32.0 29.1 28.4 20.4 25.5 21.1 19.8 21.5 30.8 14.9 15.6 27.4 19.7 17.4 20.4 35.3 34.1 14.4 21.3 57.3 21.2 21.9 38.6 20.6 SYNC "SYNC1, SYNCOILIN" ENSG00000162520 "Syncoilin, intermediate filament protein" Q9H7C4 1 32679906-32703596 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "skeletal muscle: 106.8;smooth muscle: 54.1;tongue: 73.4" "Cell type enhanced" "Detected in many" "Horizontal cells: 74.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 121.0;U-138 MG: 113.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA028311, HPA063549" Enhanced Approved "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus, Vesicles" "HPA028311: AB_2672554, HPA063549: " "unprognostic (3.99e-1)" "unprognostic (6.04e-3)" "unprognostic (2.02e-2)" "unprognostic (7.60e-3)" "unprognostic (1.99e-2)" "unprognostic (5.07e-2)" "unprognostic (5.05e-2)" "unprognostic (5.44e-3)" "unprognostic (1.71e-1)" "unprognostic (1.79e-2)" "unprognostic (5.04e-2)" "unprognostic (3.71e-1)" "unprognostic (1.32e-4)" "unprognostic (1.56e-2)" "unprognostic (1.33e-1)" "unprognostic (1.45e-1)" "unprognostic (8.15e-4)" 10.5 8.5 6.4 15.6 6.1 0.7 5.4 6.7 6.6 9.7 6.1 11.6 6.5 10.9 4.9 17.9 7.4 9.5 17.3 5.8 7.9 2.4 2.2 10.5 6.4 8.3 8.7 3.7 2.6 4.7 0.7 2.5 7.9 13.1 8.7 0.4 9.6 14.6 106.8 2.5 7.3 54.1 9.0 6.2 9.0 9.7 7.4 1.1 4.5 73.4 1.7 12.3 2.9 8.2 8.7 7.0 11.2 19.3 19.4 30.5 6.6 41.9 81.5 28.7 19.6 1.2 24.8 23.9 13.0 121.0 43.4 5.8 1.0 0.7 16.2 12.4 0.8 26.1 22.6 18.0 16.4 33.0 12.0 46.6 2.9 31.6 1.1 86.1 9.0 17.2 19.6 26.2 24.3 4.2 32.0 8.9 5.9 11.2 9.6 34.5 36.5 12.7 32.6 14.2 18.1 1.7 57.1 17.6 21.7 22.2 16.0 10.4 14.4 113.0 19.4 69.4 18.8 11.4 21.1 30.2 39.0 10.4 98.3 5.9 7.7 6.1 6.1 9.6 8.1 6.9 6.9 6.4 9.7 5.2 6.2 7.0 0.9 9.1 9.5 12.3 7.9 12.0 6.4 6.1 6.7 6.6 5.8 7.9 8.3 8.7 7.9 9.0 7.4 8.2 10.6 9.6 9.8 15.7 15.1 22.0 14.2 14.5 8.0 50.2 20.6 7.0 1.0 20.0 14.1 9.2 39.6 9.4 20.7 8.3 5.9 11.7 11.2 12.9 25.0 13.1 7.3 16.0 12.2 5.4 9.3 17.1 0.5 16.3 22.2 12.4 22.9 19.1 5.4 74.0 13.2 8.4 8.2 17.7 23.2 14.8 41.7 7.3 33.8 7.5 11.4 20.0 34.0 15.1 11.6 7.9 7.9 64.3 5.7 16.0 10.7 10.1 6.0 53.9 19.7 16.6 12.8 32.8 36.0 7.2 22.3 5.1 15.3 9.4 12.6 9.4 SYNGR3 ENSG00000127561 "Synaptogyrin 3" O43761 16 1989660-1994275 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 122.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.2;Inhibitory neurons: 33.7;Spermatogonia: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.0;T-cells: 1.1" "Cell line enhanced" "Detected in many" "HDLM-2: 49.9;HMC-1: 30.3;Karpas-707: 25.8;SK-BR-3: 32.1;U-266/70: 40.2" "CAB034278, HPA042842" Enhanced Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB034278: AB_2200905, HPA042842: AB_2678198" "unprognostic (8.89e-3)" "prognostic favorable (6.92e-4)" "unprognostic (6.07e-3)" "unprognostic (2.94e-3)" "unprognostic (2.92e-2)" "unprognostic (8.06e-3)" "unprognostic (2.52e-1)" "unprognostic (5.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.06e-1)" "unprognostic (3.69e-3)" "unprognostic (1.05e-1)" "prognostic favorable (7.12e-7)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.79e-1)" "unprognostic (8.78e-2)" 0.3 9.4 83.0 2.9 86.4 0.9 0.3 35.7 106.5 0.5 10.6 5.3 1.3 0.2 0.0 0.5 0.4 0.4 0.9 74.7 110.7 3.8 0.3 1.0 3.2 88.2 95.3 0.6 0.8 7.3 12.3 1.6 122.6 0.8 1.1 9.5 1.1 0.1 0.1 0.6 5.9 0.7 34.3 2.5 2.3 5.6 121.3 0.5 0.4 0.0 3.7 0.4 1.3 70.5 0.9 4.0 3.7 0.5 0.4 0.4 4.5 1.9 3.1 1.5 1.2 6.3 2.9 6.2 1.4 1.4 4.1 3.5 4.1 0.5 0.4 49.9 2.9 0.1 5.9 3.1 2.1 0.0 30.3 0.9 0.2 0.1 1.0 7.2 0.4 1.9 17.9 25.8 0.7 4.7 0.3 0.3 19.0 0.7 1.8 0.0 0.5 4.9 2.4 0.1 8.6 10.7 4.4 32.1 0.4 2.0 4.5 0.4 0.7 0.9 14.5 0.1 0.7 40.2 5.0 7.2 0.6 5.5 0.6 0.0 0.3 0.0 0.3 0.1 0.8 1.2 0.6 1.1 0.3 1.9 0.7 0.3 0.0 2.0 0.3 0.0 0.6 0.4 83.0 86.4 35.7 106.5 74.7 110.7 88.2 95.3 122.6 34.3 121.3 70.5 0.1 0.0 0.6 3.3 5.0 0.3 0.8 0.6 1.2 5.0 0.2 0.3 5.4 0.0 0.6 0.0 2.1 0.5 2.1 0.9 1.9 2.0 0.8 0.0 0.1 0.5 0.0 0.0 24.2 0.5 0.8 1.2 0.5 0.1 1.3 1.4 0.0 0.0 0.3 6.7 33.7 0.5 0.0 0.6 0.4 0.5 0.0 0.5 0.0 1.9 2.7 1.1 2.1 2.5 3.5 1.2 0.0 0.0 2.3 5.5 0.1 0.1 0.9 2.1 0.0 0.1 0.3 3.0 8.6 0.4 0.3 3.1 2.9 0.4 0.3 1.7 SYNPO KIAA1029 ENSG00000171992 Synaptopodin Q8N3V7 5 150601080-150659207 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 369.6;skeletal muscle: 1296.3;tongue: 502.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 264.7;Distal enterocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.0" "Lineage enriched" "Detected in single" 10 "B-cells: 1.0" "Cell line enhanced" "Detected in many" "BEWO: 88.4;EFO-21: 72.8;HUVEC TERT2: 72.7;TIME: 178.0;U-87 MG: 152.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033265, HPA034631, CAB037325, HPA071347" Enhanced Supported "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "Actin filaments" "CAB033265: AB_2201163, CAB037325: , HPA034631: AB_10669994, HPA071347: AB_2732179" "unprognostic (2.09e-2)" "unprognostic (7.72e-3)" "unprognostic (3.95e-2)" "unprognostic (2.78e-3)" "unprognostic (3.07e-2)" "unprognostic (1.66e-2)" "unprognostic (1.76e-1)" "unprognostic (1.41e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "unprognostic (1.17e-1)" "unprognostic (4.86e-2)" "prognostic unfavorable (1.53e-6)" "unprognostic (1.23e-1)" "unprognostic (5.72e-2)" "unprognostic (2.21e-2)" "unprognostic (6.35e-2)" 91.8 112.1 103.5 21.3 60.7 0.3 48.6 0.0 88.9 23.2 0.8 37.4 31.4 38.7 20.9 31.0 30.8 32.2 369.6 91.2 5.2 60.6 38.5 72.1 10.6 18.2 8.5 34.6 32.9 17.1 21.6 23.8 5.2 46.0 17.5 10.0 21.6 29.1 1296.3 15.4 39.6 38.9 20.6 38.9 34.9 17.0 5.1 6.6 31.1 502.1 11.1 56.8 22.3 34.9 0.5 24.2 0.2 0.3 3.5 3.2 88.4 13.8 18.9 4.6 3.7 21.6 9.7 0.1 72.8 19.9 29.2 8.9 0.1 13.5 1.9 0.2 0.2 0.0 37.4 4.7 19.6 0.0 0.9 3.7 21.3 5.2 3.7 27.5 72.7 0.2 0.2 0.2 4.4 1.6 0.1 0.7 2.8 9.3 11.6 0.5 0.7 0.2 3.4 1.9 8.5 39.3 19.9 21.6 0.7 31.1 1.6 6.6 178.0 17.4 53.2 0.4 3.6 0.8 0.2 1.3 152.5 0.3 11.6 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 103.5 60.7 0.0 88.9 91.2 5.2 18.2 8.5 5.2 20.6 5.1 34.9 51.1 35.3 12.2 1.3 4.8 4.6 3.0 32.6 1.8 1.9 6.4 2.5 264.7 27.1 17.0 7.3 2.1 14.8 0.5 70.5 0.0 43.7 1.7 0.4 0.4 56.3 13.8 2.7 22.5 34.5 6.0 19.9 4.6 0.5 0.0 40.9 62.8 40.0 2.1 0.0 5.7 8.4 2.0 10.8 5.1 3.4 2.8 0.9 5.4 6.5 24.0 7.2 0.0 2.5 1.3 35.6 24.4 27.8 0.6 5.7 52.6 4.4 7.6 0.8 46.0 18.0 29.2 1.2 0.8 1.4 2.3 25.9 1.6 8.6 11.8 3.6 SYNPO2L FLJ12921 ENSG00000166317 "Synaptopodin 2 like" Q9H987 10 73644881-73663803 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "heart muscle: 262.3;skeletal muscle: 279.2;tongue: 87.2" "Cell type enriched" "Detected in some" 52 "Cardiomyocytes: 665.1" "Group enriched" "Detected in some" 6 "breast cancer: 1.5;head and neck cancer: 1.4;prostate cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CACO-2: 4.1;HSkMC: 3.2;RH-30: 3.0;SK-BR-3: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA055192, HPA057142" Enhanced Supported "Nuclear speckles,Cell Junctions,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Nuclear speckles" "Cell Junctions, Cytosol" "HPA055192: AB_2682732, HPA057142: AB_2683348" "unprognostic (2.75e-1)" "unprognostic (1.58e-1)" "unprognostic (1.20e-3)" "unprognostic (3.65e-3)" "unprognostic (1.27e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "unprognostic (4.54e-2)" "unprognostic (3.30e-1)" "unprognostic (2.49e-2)" "unprognostic (4.50e-2)" "unprognostic (2.32e-1)" "unprognostic (7.44e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-1)" "unprognostic (1.72e-2)" "unprognostic (1.34e-1)" 0.1 0.5 0.7 0.1 0.7 0.3 3.6 0.8 0.9 0.4 0.1 0.0 0.1 0.1 0.1 11.8 0.1 0.1 262.3 0.7 0.5 0.1 0.1 1.2 0.2 0.7 0.6 0.2 0.4 0.0 0.1 0.6 0.5 3.1 0.0 0.4 4.8 0.0 279.2 0.3 0.0 0.0 0.5 0.2 0.1 0.3 0.6 0.1 0.2 87.2 0.2 0.0 1.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.5 0.6 0.1 0.0 4.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.0 0.3 0.1 0.0 3.2 0.0 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.1 0.1 0.1 0.0 3.2 0.0 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.2 0.0 0.0 0.7 0.7 0.8 0.9 0.7 0.5 0.7 0.6 0.5 0.5 0.6 0.7 0.5 3.2 0.0 0.3 0.9 1.5 1.4 0.0 2.2 1.9 1.0 0.8 665.1 0.0 0.7 0.0 2.1 0.2 0.5 0.0 0.0 0.0 2.6 0.1 0.4 5.0 0.0 0.0 0.3 0.0 0.2 12.6 0.0 0.3 1.3 0.3 0.0 0.4 0.2 0.0 0.9 0.0 0.0 0.6 2.1 1.1 0.9 0.8 1.8 1.0 0.3 0.4 0.0 1.5 1.1 0.0 0.0 0.4 0.3 0.9 0.0 0.2 0.7 1.2 0.0 12.0 5.2 0.8 1.3 0.4 0.4 0.0 0.7 0.2 0.0 1.0 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 SYTL2 "CHR11SYT, exophilin-4, FLJ20163, FLJ21219, KIAA1597, MGC102768, PPP1R151, SGA72M, SLP2" ENSG00000137501 "Synaptotagmin like 2" Q9HCH5 11 85694224-85811159 "Plasma proteins, Predicted intracellular proteins, Transporters" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 74.2;stomach 1: 127.7" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 382.2;granulocytes: 130.8;Intestinal goblet cells: 185.9;Respiratory ciliated cells: 138.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "gdT-cell: 14.0;MAIT T-cell: 23.7" "Lineage enriched" "Detected in many" 5 "T-cells: 23.7" "Cell line enhanced" "Detected in many" "MCF7: 91.1;OE19: 148.1;RH-30: 175.8;RPTEC TERT1: 124.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039651 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Nucleoplasm, Golgi apparatus" "Plasma membrane" "HPA039651: AB_10795153" "unprognostic (8.07e-3)" "unprognostic (6.72e-3)" "prognostic favorable (2.67e-4)" "unprognostic (9.34e-4)" "unprognostic (6.60e-3)" "unprognostic (2.19e-4)" "unprognostic (2.24e-2)" "unprognostic (5.37e-2)" "unprognostic (5.56e-2)" "unprognostic (5.45e-2)" "unprognostic (1.92e-2)" "unprognostic (2.97e-2)" "unprognostic (2.85e-2)" "unprognostic (4.03e-1)" "unprognostic (1.87e-2)" "unprognostic (9.72e-2)" "prognostic favorable (9.07e-4)" 16.7 9.6 19.3 12.9 24.6 3.3 16.0 8.7 35.7 10.7 11.9 51.7 21.6 9.1 16.3 17.0 7.6 27.8 8.4 29.0 25.1 20.2 6.9 14.8 11.1 26.4 14.0 4.8 2.7 6.4 6.1 18.2 17.9 13.6 74.2 13.3 8.9 9.8 5.1 6.8 25.0 10.2 15.6 10.4 127.7 5.1 13.8 7.1 4.7 2.7 6.8 50.9 7.4 29.1 3.5 8.0 12.2 1.0 2.8 15.4 0.2 30.3 39.4 26.3 59.2 34.7 4.5 0.7 11.1 21.3 38.0 22.3 0.8 2.7 34.5 2.4 0.2 0.0 0.2 0.3 1.8 2.7 0.5 19.6 3.8 56.8 0.8 6.2 0.2 1.0 0.4 0.4 33.6 91.1 0.1 0.9 20.6 148.1 13.6 1.3 175.8 0.1 124.2 46.8 0.3 0.6 6.7 5.4 3.0 10.2 0.6 0.5 0.1 40.8 15.6 25.9 1.5 0.2 0.0 16.1 41.9 0.5 25.7 0.0 0.0 0.0 14.0 0.0 23.7 0.0 2.8 8.4 0.0 0.1 2.3 4.1 0.0 4.6 0.1 1.0 1.1 2.6 19.3 24.6 8.7 35.7 29.0 25.1 26.4 14.0 17.9 15.6 13.8 29.1 7.5 22.4 32.5 15.3 3.0 3.6 11.7 15.8 1.8 10.4 45.4 14.0 2.3 8.6 62.1 68.0 8.4 0.7 45.6 115.2 0.0 9.1 1.2 8.0 2.2 6.4 19.2 4.0 103.9 16.9 0.4 11.5 382.2 2.3 130.8 0.8 5.0 0.5 0.5 1.7 23.2 185.9 2.0 5.9 5.0 0.9 1.8 4.6 10.6 20.6 1.6 14.0 63.8 35.7 91.9 16.5 40.6 30.1 31.6 30.7 16.3 8.6 138.4 8.1 32.9 42.1 59.8 3.6 2.6 2.2 5.7 0.4 50.1 2.3 36.7 60.9 SYVN1 "DER3, HRD1" ENSG00000162298 "Synoviolin 1" Q86TM6 11 65121780-65134532 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Stress response, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 72.9;Plasma cells: 90.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 205.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005480, HPA024300, CAB037030" Enhanced Supported "Nucleoplasm,Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" Nucleoplasm "Endoplasmic reticulum, Plasma membrane" "CAB037030: AB_1840939, HPA005480: AB_1079084, HPA024300: AB_1851073" "unprognostic (1.12e-1)" "unprognostic (3.10e-1)" "unprognostic (1.22e-1)" "unprognostic (2.17e-2)" "unprognostic (2.85e-2)" "prognostic favorable (6.88e-4)" "unprognostic (7.67e-2)" "unprognostic (2.50e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-1)" "unprognostic (1.59e-1)" "unprognostic (1.12e-1)" "unprognostic (1.77e-2)" "unprognostic (1.56e-2)" "unprognostic (4.89e-1)" "unprognostic (3.85e-2)" "unprognostic (1.16e-1)" 29.2 40.3 19.3 37.1 25.6 31.0 27.6 23.2 21.4 30.7 26.7 29.2 26.1 29.1 38.8 28.4 30.6 19.7 25.3 18.6 21.2 24.5 117.5 27.0 60.9 27.9 25.6 30.9 90.9 35.0 38.2 26.2 24.6 28.5 29.0 18.7 55.9 30.3 34.2 29.3 39.4 25.9 22.8 51.2 39.4 24.3 23.4 18.3 43.4 19.0 81.1 25.8 24.8 25.9 32.4 40.6 24.0 32.5 59.8 33.8 23.8 32.8 33.5 40.9 28.8 22.2 55.0 181.0 43.8 42.4 53.8 48.8 26.4 33.3 33.6 28.4 20.0 28.6 46.8 50.2 72.3 43.3 49.6 43.3 59.0 36.1 81.0 36.4 27.0 19.0 36.4 90.1 24.3 47.9 19.1 31.2 26.1 33.6 28.0 31.9 20.3 74.0 25.7 31.5 15.6 32.0 30.4 74.1 53.3 21.0 55.4 28.2 25.9 28.3 18.6 51.2 22.4 178.1 134.2 205.9 38.1 21.8 32.3 16.8 7.4 14.0 7.4 4.7 6.5 21.9 5.2 6.9 4.4 22.6 3.7 3.9 7.0 3.5 4.7 18.4 5.3 6.6 19.3 25.6 23.2 21.4 18.6 21.2 27.9 25.6 24.6 22.8 23.4 25.9 11.5 16.0 21.4 11.1 43.5 17.6 6.9 13.8 12.0 10.7 21.0 15.5 4.0 22.8 20.8 11.0 33.3 14.5 16.4 23.1 1.9 13.6 6.6 14.2 16.2 11.3 8.4 13.2 9.6 18.9 16.5 14.2 17.9 22.1 1.3 10.1 15.0 72.9 15.1 13.5 9.5 33.6 16.2 15.3 13.2 4.1 20.5 10.8 12.4 9.4 10.5 11.0 13.4 13.0 15.8 18.2 11.7 13.2 90.5 14.9 14.0 7.7 15.1 18.7 13.1 11.9 10.7 19.3 13.2 9.7 16.1 42.8 11.7 13.6 18.6 13.8 TACC2 "AZU-1, ECTACC" ENSG00000138162 "Transforming acidic coiled-coil containing protein 2" O95359 10 121989163-122254545 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 251.7;skeletal muscle: 387.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 210.1;Syncytiotrophoblasts: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTCEpi: 86.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031020, HPA031021, HPA061394" Enhanced Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 32000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Cytosol" "Plasma membrane" "HPA031020: AB_10669988, HPA031021: AB_2673701, HPA061394: AB_2684500" "unprognostic (3.28e-2)" "unprognostic (4.88e-2)" "unprognostic (1.75e-2)" "unprognostic (7.07e-2)" "unprognostic (2.26e-1)" "unprognostic (1.14e-1)" "unprognostic (9.15e-2)" "unprognostic (8.43e-3)" "unprognostic (1.14e-1)" "unprognostic (3.51e-1)" "unprognostic (2.13e-1)" "unprognostic (1.83e-2)" "prognostic favorable (2.50e-10)" "unprognostic (7.02e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (8.45e-4)" "unprognostic (1.61e-1)" 22.1 15.3 18.2 5.3 18.6 0.2 20.9 23.6 22.7 32.3 28.6 91.5 15.3 26.1 9.2 64.2 32.9 12.9 251.7 19.1 18.8 33.9 18.8 68.7 1.0 16.0 16.9 8.8 25.3 36.4 58.7 21.6 14.8 67.7 20.7 7.2 60.7 13.5 387.1 103.3 35.7 22.0 11.8 4.2 49.1 5.8 16.9 5.7 50.7 159.0 5.7 62.4 49.1 17.7 17.8 55.1 26.5 15.2 7.4 7.4 31.7 7.7 20.7 10.5 7.3 22.7 28.9 0.0 7.0 12.3 12.1 58.1 8.5 20.9 10.9 3.0 4.4 0.0 7.7 43.8 11.5 0.0 0.3 3.4 86.0 5.6 36.6 8.6 22.2 0.1 4.5 0.6 10.4 23.5 0.2 9.9 15.7 27.6 24.8 0.3 15.2 8.5 28.9 26.9 17.6 14.2 12.7 52.0 29.5 7.6 10.2 0.4 20.6 4.7 3.5 11.8 14.5 2.4 11.7 0.3 8.7 0.1 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.2 18.6 23.6 22.7 19.1 18.8 16.0 16.9 14.8 11.8 16.9 17.7 15.5 83.3 94.1 16.3 0.7 33.6 49.7 54.3 33.0 21.6 23.4 14.1 210.1 8.6 70.7 36.8 0.0 53.3 0.4 75.2 1.9 8.2 2.4 88.4 11.0 21.3 30.0 0.0 32.8 14.2 4.4 21.2 38.7 62.8 7.0 0.1 6.1 18.9 6.5 43.7 48.2 38.8 57.0 0.3 4.3 2.6 6.8 1.9 7.2 7.5 0.1 1.1 0.0 80.9 7.6 19.4 47.1 7.5 0.2 49.6 36.5 13.5 84.9 2.7 13.1 27.2 23.7 0.5 8.2 79.5 54.0 228.5 2.6 2.8 41.9 80.5 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 184.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.7;Kupffer cells: 2.4;Leydig cells: 2.8" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 4.2;U-87 MG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 0.9 0.3 1.3 2.5 1.2 0.4 0.8 1.5 1.7 10.3 0.2 184.0 5.0 25.2 0.2 14.7 20.4 0.5 3.2 1.7 0.1 0.3 0.5 0.7 0.3 0.0 0.2 1.8 0.3 0.0 0.2 0.2 0.1 6.2 9.1 4.1 0.5 1.1 2.8 1.1 31.4 33.1 0.0 0.3 37.9 0.7 0.0 0.1 0.4 0.2 0.1 32.3 8.5 0.4 0.9 0.6 0.2 0.3 1.4 0.1 0.1 0.2 0.1 0.2 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.8 0.1 0.0 1.4 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.2 0.2 0.8 0.9 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.6 1.2 4.2 0.1 0.5 0.1 0.3 1.4 0.2 0.6 0.5 0.5 0.6 0.1 2.3 0.1 0.8 0.2 0.4 0.0 0.1 1.3 0.1 0.3 0.2 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 1.3 1.2 1.5 1.7 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.0 0.5 0.3 0.1 0.6 0.2 0.2 0.0 0.2 1.1 1.4 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.6 0.0 0.2 1.4 0.1 1.2 6.7 0.1 0.3 0.0 2.4 0.4 0.1 2.8 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.4 0.1 1.5 0.2 0.0 1.1 0.7 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.4 TACSTD2 "EGP-1, GA733-1, M1S1, TROP2" ENSG00000184292 "Tumor associated calcium signal transducer 2" P09758 1 58575433-58577252 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Tumor antigen" "Amyloidosis, Corneal dystrophy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 989.6;salivary gland: 468.5;skin 1: 438.8" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 6559.0;Basal respiratory cells: 3141.0;Club cells: 2499.0;Prostatic glandular cells: 3724.1;Squamous epithelial cells: 2716.6;Urothelial cells: 8102.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "eosinophil: 15.0" "Group enriched" "Detected in many" 79 "dendritic cells: 4.3;granulocytes: 15.0;monocytes: 4.2" "Cell line enhanced" "Detected in many" "A-431: 766.6;CAPAN-2: 1005.9;HaCaT: 1010.0;RT4: 355.3" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA043104, HPA055067, CAB072852" Enhanced Supported "Nucleoli,Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "Nucleoli, Vesicles" "CAB072852: , HPA043104: AB_10960710, HPA055067: AB_2682687" "unprognostic (1.80e-2)" "unprognostic (3.08e-1)" "unprognostic (3.67e-3)" "unprognostic (1.22e-1)" "unprognostic (5.70e-2)" "unprognostic (2.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.79e-1)" "unprognostic (1.99e-1)" "unprognostic (1.03e-2)" "unprognostic (1.71e-2)" "unprognostic (7.91e-2)" "prognostic favorable (3.99e-4)" "unprognostic (7.10e-2)" "unprognostic (2.55e-1)" "unprognostic (6.91e-3)" "unprognostic (2.50e-1)" 4.8 1.2 0.2 1.3 0.4 13.5 135.8 0.2 0.4 218.6 1.9 1.1 0.7 19.1 25.3 989.6 27.7 13.0 0.8 0.3 0.3 137.9 4.0 71.2 1.0 0.2 0.3 1.5 81.1 3.5 2.4 17.7 0.2 126.8 0.9 0.0 468.5 97.1 1.9 438.8 1.2 2.0 0.2 1.0 65.7 0.5 0.3 9.2 5.0 0.3 180.0 234.6 375.0 0.6 766.6 0.1 0.0 1.5 0.0 0.0 280.1 0.2 0.0 0.0 0.1 0.7 1005.9 0.1 94.7 64.2 0.1 1010.0 0.0 186.5 0.0 0.7 0.0 0.2 19.7 0.3 0.3 0.1 0.8 0.2 274.5 0.4 11.3 0.0 42.5 0.0 0.2 1.3 0.0 166.3 0.6 1.1 0.5 167.0 1.4 0.2 0.1 0.6 137.0 355.3 0.2 0.3 32.4 264.9 1.0 3.2 173.6 1.5 45.4 1.0 1.7 0.8 1.7 0.4 0.9 0.7 1.0 0.3 0.7 0.0 4.2 15.0 0.0 0.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.8 0.2 0.4 0.2 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.3 0.6 9.0 346.1 109.2 0.0 3.1 1490.5 6559.0 3141.0 1226.5 0.0 789.8 445.6 0.4 338.8 2499.0 1278.2 0.0 107.1 9.1 2.8 43.0 2165.2 0.0 482.3 48.6 60.4 0.0 0.0 0.1 1263.4 8.1 36.3 143.2 608.7 8.8 0.2 1.4 0.5 8.8 0.0 0.0 8.5 1143.4 0.8 203.4 0.0 0.0 34.8 113.8 0.0 31.3 0.0 0.0 0.0 0.6 1778.0 3.6 0.0 1.4 3724.1 0.2 3.4 1080.4 0.0 0.0 1.3 142.4 0.4 1.1 2716.6 1531.8 78.4 32.8 0.0 1.5 8102.8 TAS2R10 "T2R10, TRB2" ENSG00000121318 "Taste 2 receptor member 10" Q9NYW0 12 10825317-10826358 "G-protein coupled receptors, Predicted membrane proteins" "Sensory transduction, Taste" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "Astrocytes: 6.2;Excitatory neurons: 14.4;Inhibitory neurons: 14.4;Microglial cells: 4.7;Oligodendrocyte precursor cells: 14.1;Oligodendrocytes: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA070201 Approved "Vesicles,Plasma membrane,Actin filaments" NA NA "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Vesicles, Plasma membrane" "Actin filaments" "HPA070201: " "unprognostic (1.28e-1)" "unprognostic (3.89e-4)" "unprognostic (1.77e-1)" "unprognostic (1.82e-2)" "unprognostic (1.10e-1)" "unprognostic (5.82e-3)" "unprognostic (3.86e-1)" "unprognostic (7.72e-2)" "unprognostic (5.27e-2)" "unprognostic (1.67e-1)" "unprognostic (1.24e-2)" "unprognostic (1.20e-1)" "unprognostic (4.16e-5)" "unprognostic (5.41e-2)" "unprognostic (3.18e-2)" "unprognostic (2.87e-2)" "unprognostic (2.56e-3)" 0.2 0.6 0.1 0.0 0.1 0.0 0.2 0.1 0.4 0.3 0.0 0.2 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.2 0.0 0.1 0.1 0.3 0.2 0.0 0.4 0.0 0.1 0.2 0.0 0.3 0.4 0.0 0.0 0.1 0.3 0.0 0.0 0.3 0.2 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.0 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 6.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 14.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.7 0.0 0.1 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 14.1 11.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 TASP1 "C20orf13, dJ585I14.2, FLJ20212" ENSG00000089123 "Taspase 1" Q9H6P5 20 13389392-13638932 "Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 136.1;Inhibitory neurons: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030824, HPA030825" Uncertain Approved "Plasma membrane" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA030824: AB_10600327, HPA030825: AB_10601575" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (2.47e-1)" "unprognostic (6.46e-2)" "unprognostic (3.44e-3)" "unprognostic (9.85e-2)" "unprognostic (9.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.67e-2)" 7.0 4.5 1.0 4.3 1.7 4.9 6.8 1.5 2.9 6.5 3.9 5.2 3.7 6.8 6.0 4.8 8.1 4.5 5.7 1.2 2.7 5.4 4.5 6.0 5.7 1.3 1.7 5.6 5.9 8.7 7.4 6.5 1.0 5.2 5.7 6.4 6.0 4.6 2.9 5.5 4.6 5.1 0.5 5.6 5.6 6.1 2.3 12.5 7.8 4.3 5.2 5.6 6.2 2.9 13.1 7.7 3.1 3.7 3.6 5.6 6.0 5.3 7.6 6.1 7.1 16.0 13.3 5.9 3.6 7.0 6.7 17.2 4.9 18.4 7.1 3.5 5.8 11.8 4.7 20.3 7.4 16.0 4.1 6.3 12.1 6.2 15.0 3.7 6.1 10.4 10.7 0.2 5.4 15.8 30.7 8.7 4.2 11.7 3.5 4.8 12.7 9.1 8.5 9.8 8.3 5.7 8.2 15.8 10.2 4.4 8.3 5.8 5.9 5.7 4.0 5.9 7.6 11.3 16.7 4.2 3.2 3.6 5.5 2.3 4.5 4.9 12.7 6.5 9.0 12.1 12.8 10.0 5.0 9.8 18.6 14.4 2.5 14.8 6.5 19.5 13.3 7.1 1.0 1.7 1.5 2.9 1.2 2.7 1.3 1.7 1.0 0.5 2.3 2.9 10.7 6.4 7.7 31.3 19.6 14.1 13.2 11.1 24.5 14.9 10.0 8.8 6.4 17.2 8.8 5.5 10.4 12.0 13.8 3.9 7.9 12.1 20.1 15.7 10.6 6.6 3.6 7.8 136.1 6.0 12.3 15.9 13.3 9.5 15.2 5.2 3.6 6.4 4.7 11.8 131.0 9.9 4.1 3.0 4.7 4.8 3.4 5.8 10.6 35.6 2.9 6.6 11.3 50.3 49.6 8.6 11.4 3.4 13.3 8.0 5.3 12.2 23.5 17.0 6.6 23.7 17.0 29.3 9.3 18.0 12.1 7.0 12.7 10.2 7.7 8.9 TAZ "BTHS, CMD3A, EFE, EFE2, G4.5, TAZ1, XAP-2" ENSG00000102125 Tafazzin Q16635 X 154411524-154421726 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039557 Approved Approved "Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA039557: AB_10672899" "unprognostic (1.14e-1)" "prognostic favorable (5.70e-4)" "unprognostic (4.94e-3)" "unprognostic (1.43e-1)" "unprognostic (8.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.56e-2)" "unprognostic (8.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (4.68e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (4.00e-3)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" 19.0 13.8 37.2 8.5 38.1 41.4 17.2 38.1 44.4 18.1 37.0 18.3 9.7 15.1 7.6 21.7 16.6 8.7 43.5 37.0 37.0 22.3 21.9 21.4 17.9 39.3 37.6 18.5 21.3 12.1 14.5 6.6 38.5 17.9 11.7 8.4 13.6 10.2 47.0 18.7 22.9 12.3 37.7 39.2 17.4 4.5 37.9 14.1 18.5 65.6 16.0 18.4 18.4 39.4 24.5 28.6 9.3 11.7 18.3 13.4 18.4 6.9 21.0 15.3 17.1 8.5 29.6 28.2 43.6 16.4 36.6 28.4 17.2 16.6 12.3 25.5 19.6 5.5 20.0 16.4 25.8 12.3 11.8 15.4 35.6 11.7 31.7 12.9 25.6 30.9 12.1 34.9 18.1 17.6 29.0 33.2 2.4 24.9 27.9 21.4 16.2 40.1 24.2 9.0 11.8 17.9 5.3 17.9 26.6 11.1 10.5 16.0 15.5 10.4 11.9 25.5 15.2 55.9 30.6 66.2 13.7 36.6 13.3 5.8 11.1 17.5 12.4 10.4 11.5 12.5 16.6 15.5 14.5 18.7 14.1 12.0 9.9 12.7 7.8 7.9 15.4 9.4 37.2 38.1 38.1 44.4 37.0 37.0 39.3 37.6 38.5 37.7 37.9 39.4 36.2 6.4 11.8 37.2 29.3 10.8 7.9 10.5 14.8 21.6 11.1 15.6 21.1 14.3 13.0 9.2 18.8 5.0 29.7 13.6 5.9 14.7 1.1 6.5 9.6 18.5 6.1 9.7 22.4 16.5 10.1 12.4 23.4 9.6 18.4 19.2 15.0 7.9 24.4 10.1 28.4 15.9 12.2 19.9 16.5 2.0 11.5 20.4 14.2 14.0 21.7 14.2 15.5 23.1 39.7 13.4 12.2 9.1 17.2 8.3 19.6 5.9 8.0 25.6 13.1 12.4 11.3 10.4 3.8 16.8 11.2 2.9 25.6 9.2 15.8 6.7 TBC1D10A "AC004997.C22.2, EPI64, TBC1D10" ENSG00000099992 "TBC1 domain family member 10A" Q9BXI6 22 30291990-30326947 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007725, HPA008142, HPA076041" Approved Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA007725: AB_2667907, HPA008142: AB_1080209, HPA076041: AB_2686772" "unprognostic (3.37e-2)" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (1.10e-2)" "unprognostic (2.11e-3)" "unprognostic (1.20e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (4.28e-1)" "unprognostic (6.40e-2)" "unprognostic (1.08e-1)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.05e-2)" "unprognostic (7.52e-2)" 22.6 17.0 6.9 10.2 8.2 8.2 23.7 5.8 10.2 29.6 9.3 18.3 8.6 14.7 4.6 44.1 14.9 12.7 11.2 7.5 9.3 21.3 17.9 23.7 17.2 7.4 8.1 21.1 10.8 24.5 19.5 17.5 7.0 21.3 5.5 10.8 23.2 12.9 5.6 45.3 17.3 6.8 6.2 24.2 17.3 21.6 9.7 18.4 19.0 6.9 10.4 19.9 39.9 6.4 18.9 7.1 2.9 9.0 8.4 10.8 23.9 10.7 14.9 11.8 18.7 8.4 7.2 9.5 10.2 17.8 16.2 18.3 4.3 9.9 6.2 7.2 12.4 2.6 6.4 6.0 21.9 3.7 12.9 14.0 15.5 23.4 4.0 12.3 5.5 20.5 5.1 8.8 8.9 22.1 26.9 7.9 1.9 33.9 9.5 12.3 12.4 8.8 11.6 17.9 4.9 3.8 11.0 15.7 24.5 7.8 13.8 2.3 10.8 22.9 10.4 13.1 5.8 8.8 4.2 8.3 15.6 5.6 13.1 37.5 14.9 37.9 26.6 30.1 29.3 13.4 30.9 27.2 21.7 20.7 40.7 34.0 10.6 24.3 45.5 37.5 28.8 28.4 6.9 8.2 5.8 10.2 7.5 9.3 7.4 8.1 7.0 6.2 9.7 6.4 27.8 6.4 3.4 24.8 18.2 49.2 40.2 40.3 32.5 7.8 18.4 12.4 2.7 14.3 23.6 5.5 18.8 57.6 19.5 26.8 23.5 20.1 10.7 8.8 5.4 14.4 10.7 3.0 3.0 10.2 80.6 18.3 19.4 16.4 9.5 20.1 11.0 8.6 27.5 1.7 3.5 14.2 18.3 12.9 46.0 6.9 21.8 15.9 26.6 10.3 78.1 28.1 28.8 2.5 1.0 18.7 18.7 9.1 12.3 24.3 14.9 20.5 6.6 39.3 39.5 7.4 17.1 33.2 13.5 27.6 37.1 116.3 28.0 20.2 11.0 28.3 TBC1D2 "Armus, PARIS1, TBC1D2A" ENSG00000095383 "TBC1 domain family member 2" Q9BYX2 9 98199011-98255649 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 57.7;Oligodendrocytes: 64.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 27.5" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 77.0;HaCaT: 98.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA030871, HPA076521" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA Yes "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane, Cytosol" "HPA030871: AB_10670046, HPA076521: " "unprognostic (2.32e-2)" "unprognostic (1.11e-1)" "unprognostic (1.06e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-2)" "prognostic unfavorable (2.77e-4)" "unprognostic (1.86e-1)" "unprognostic (2.11e-1)" "unprognostic (1.74e-1)" "unprognostic (9.21e-3)" "unprognostic (6.40e-3)" "unprognostic (2.30e-1)" "unprognostic (6.07e-2)" "unprognostic (4.32e-1)" "prognostic unfavorable (5.62e-4)" "unprognostic (1.30e-2)" "unprognostic (4.30e-1)" 8.8 5.3 11.1 5.7 16.0 13.1 7.8 12.3 26.0 10.8 8.5 8.6 12.6 4.4 1.5 37.4 5.5 4.0 3.7 10.6 12.9 6.4 19.8 32.0 3.8 14.9 14.9 2.9 3.0 3.5 4.4 7.2 16.4 12.0 4.4 3.4 14.7 6.1 4.3 24.3 10.1 2.8 11.4 9.4 7.0 3.4 23.3 3.0 8.1 1.4 4.9 11.7 17.3 23.9 77.0 10.8 0.5 2.5 8.2 15.9 24.3 33.2 18.4 23.8 19.6 6.9 32.8 1.3 24.7 19.6 5.2 98.1 0.7 36.8 8.3 2.6 1.4 0.7 38.0 5.4 37.6 1.7 2.9 21.7 59.8 23.6 58.7 41.5 8.6 2.1 2.4 1.0 19.0 9.9 0.4 4.6 1.6 7.4 6.2 1.2 4.8 0.2 36.0 46.7 0.9 1.4 11.3 24.4 3.4 1.7 8.1 2.6 51.7 28.8 8.6 4.8 13.6 1.6 1.5 0.6 29.0 2.9 3.2 2.1 27.5 8.4 2.5 15.3 1.8 1.2 3.8 2.2 10.0 0.8 1.6 1.9 11.9 1.2 12.3 1.3 5.5 10.8 11.1 16.0 12.3 26.0 10.6 12.9 14.9 14.9 16.4 11.4 23.3 23.9 2.9 57.7 12.5 5.2 2.4 8.3 18.5 30.4 21.6 3.3 2.7 5.6 0.7 4.3 23.3 3.7 0.0 21.5 0.9 16.2 3.9 3.3 1.8 4.6 3.7 5.0 7.7 0.4 4.6 3.2 10.9 2.4 6.1 10.3 0.0 0.6 1.1 6.1 32.0 1.7 5.4 12.6 18.3 16.2 1.8 1.2 1.8 18.3 3.6 4.7 7.5 4.4 3.1 12.1 64.9 14.4 10.7 0.7 1.7 9.2 16.4 3.2 10.8 2.4 0.0 1.8 3.4 2.1 3.0 29.8 10.9 17.4 2.4 0.7 5.7 17.1 TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.8;Inhibitory neurons: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SCLC-21H: 34.7" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cell Junctions" "HPA044712: AB_10795619, HPA068080: AB_2685948" "prognostic unfavorable (3.22e-4)" "unprognostic (5.23e-2)" "unprognostic (4.02e-2)" "unprognostic (6.41e-2)" "unprognostic (3.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-2)" "unprognostic (1.28e-1)" "unprognostic (4.66e-3)" "unprognostic (2.02e-2)" "unprognostic (8.19e-2)" "unprognostic (7.78e-3)" "unprognostic (1.61e-1)" 3.8 3.3 7.5 1.8 8.1 2.5 2.8 3.6 10.5 2.1 0.0 2.0 2.2 1.4 2.8 1.0 2.3 1.9 3.0 8.3 3.7 4.3 3.7 3.9 1.8 2.9 2.9 1.0 10.6 1.9 2.6 2.1 3.1 2.5 0.9 4.2 16.5 3.5 3.4 1.2 1.6 1.7 1.9 2.0 2.2 1.2 4.4 0.9 3.1 1.7 1.2 1.8 0.9 2.8 3.4 6.7 4.5 9.2 5.1 5.1 3.8 6.2 3.3 4.0 3.5 6.2 2.9 8.6 5.2 4.9 1.9 6.3 7.1 2.0 2.9 9.3 8.0 8.0 9.5 5.5 3.1 5.9 3.2 1.9 2.8 3.5 1.4 2.8 5.1 3.3 9.9 4.8 3.8 6.4 4.1 11.9 4.0 3.2 4.3 20.9 8.5 6.1 2.9 2.3 34.7 8.5 3.8 15.3 2.6 1.6 4.8 5.2 5.4 7.8 8.4 7.9 6.2 3.2 3.0 11.0 3.4 8.5 7.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 7.5 8.1 3.6 10.5 8.3 3.7 2.9 2.9 3.1 1.9 4.4 2.8 4.7 28.9 26.7 15.7 1.9 0.5 3.0 1.4 1.8 19.0 17.8 10.8 6.9 10.0 6.9 5.5 43.8 1.5 5.6 2.4 33.2 5.0 0.2 2.8 10.0 5.4 11.4 6.5 29.6 6.1 1.0 5.8 5.6 4.0 3.8 6.0 10.4 17.3 3.5 26.9 34.0 2.6 6.1 5.1 3.3 1.0 9.0 3.0 1.8 6.5 3.6 13.8 6.2 25.1 9.7 5.0 2.8 6.0 1.7 3.1 1.8 3.9 3.6 25.5 0.0 11.2 3.7 8.8 5.9 1.4 1.4 0.3 2.9 3.4 4.7 1.6 TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;pancreas: 12.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.9;Inhibitory neurons: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 25.9;OE19: 11.9;RPMI-8226: 12.6;RT4: 12.8;SCLC-21H: 26.5;SK-BR-3: 16.7;T-47d: 14.5" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" 1.5 1.1 2.0 1.0 2.7 0.3 2.3 4.9 10.1 3.0 1.4 1.4 1.8 1.4 1.8 0.6 1.5 1.8 0.6 5.3 1.7 2.2 1.2 2.3 0.4 6.8 1.8 0.9 12.0 2.4 6.4 0.6 6.9 3.0 1.5 2.2 6.8 2.7 0.3 0.8 1.6 0.9 2.0 1.9 3.9 1.9 2.0 0.3 1.5 0.3 0.3 3.3 1.3 3.8 5.1 1.0 0.5 0.3 0.1 0.6 0.7 0.0 0.0 0.1 0.0 4.3 1.8 0.1 0.9 0.1 0.3 0.1 5.3 0.2 0.0 0.0 3.8 0.3 1.4 0.1 0.0 4.0 0.8 0.3 0.1 0.0 0.0 0.6 3.8 1.2 0.0 2.0 0.3 25.9 0.0 0.6 1.1 11.9 5.2 0.2 0.1 12.6 0.9 12.8 26.5 1.8 1.4 16.7 0.3 0.3 14.5 1.4 4.2 0.0 0.9 0.9 2.5 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 2.7 4.9 10.1 5.3 1.7 6.8 1.8 6.9 2.0 2.0 3.8 5.1 0.0 6.3 4.9 0.6 0.9 4.6 0.9 0.0 9.3 7.2 3.8 0.6 5.7 4.5 3.7 8.4 0.7 1.5 2.5 9.8 3.9 14.2 2.2 0.8 6.5 0.0 0.0 30.9 4.9 0.3 0.7 3.6 4.2 8.9 0.8 1.8 0.3 1.6 0.0 42.8 6.4 6.1 4.0 6.2 1.9 0.3 3.0 5.4 12.2 1.2 2.6 0.0 1.5 2.0 2.7 4.9 0.0 0.6 9.1 3.9 2.3 1.8 0.6 0.0 0.6 1.0 3.7 3.0 0.3 1.4 0.1 0.8 0.4 4.4 8.7 TBC1D9B "GRAMD9B, KIAA0676" ENSG00000197226 "TBC1 domain family member 9B" Q66K14 5 179862066-179907897 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038350 Approved Approved "Nucleoplasm,Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 15: Liver - Metabolism" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "Nucleoplasm, Nucleoli fibrillar center" "HPA038350: AB_10673170" "unprognostic (5.06e-2)" "unprognostic (1.37e-1)" "unprognostic (1.60e-2)" "unprognostic (9.53e-2)" "unprognostic (9.45e-3)" "unprognostic (4.25e-1)" "unprognostic (1.06e-1)" "unprognostic (2.84e-1)" "unprognostic (1.10e-1)" "unprognostic (5.08e-2)" "unprognostic (2.01e-1)" "unprognostic (2.28e-2)" "unprognostic (3.95e-2)" "unprognostic (1.86e-1)" "unprognostic (4.01e-2)" "prognostic unfavorable (3.99e-4)" "unprognostic (8.22e-2)" 54.9 61.8 53.9 20.8 62.2 22.8 46.3 58.1 51.1 39.3 38.6 34.1 22.8 38.9 12.0 43.9 34.2 23.8 30.9 51.4 50.1 44.8 55.0 31.7 23.9 60.5 59.8 39.0 46.4 27.0 29.2 17.2 61.6 33.6 12.1 9.1 37.0 25.0 45.9 44.4 34.4 21.1 63.4 39.5 35.5 20.5 57.2 13.1 36.3 18.7 15.3 35.1 35.7 65.9 42.7 64.0 27.4 62.4 69.9 49.0 66.8 51.0 47.2 50.1 48.4 43.8 41.9 29.3 60.2 57.8 56.6 39.6 28.3 115.9 9.8 98.0 39.1 26.0 47.3 27.9 41.5 35.1 85.0 50.6 42.6 39.2 18.9 22.6 48.4 55.3 17.7 28.1 39.5 104.2 22.7 24.5 20.3 17.4 36.5 38.7 22.1 27.8 35.1 66.8 40.1 30.4 48.2 54.5 54.9 11.0 45.0 48.8 57.2 71.2 31.9 34.8 45.2 16.8 23.3 22.7 68.0 41.7 51.7 5.0 7.8 5.5 6.1 9.2 4.8 6.3 4.2 4.9 9.3 5.1 3.9 3.5 0.9 4.2 9.2 9.5 4.0 7.1 53.9 62.2 58.1 51.1 51.4 50.1 60.5 59.8 61.6 63.4 57.2 65.9 24.9 22.4 19.2 20.2 19.7 16.6 10.2 14.6 15.4 27.8 23.9 21.6 9.5 12.8 14.0 27.6 8.4 19.8 20.4 28.4 13.7 21.1 2.4 18.2 20.2 21.0 18.0 17.5 32.1 18.0 23.6 21.1 21.9 27.0 11.4 30.0 24.3 35.2 30.7 62.2 23.6 23.9 10.2 33.5 15.7 8.2 32.3 28.6 16.0 15.9 21.4 17.8 24.7 14.6 27.0 25.2 24.3 28.6 16.4 15.3 24.4 22.6 13.3 18.0 26.3 26.7 16.4 11.1 18.5 25.0 15.6 14.1 17.9 57.1 20.5 13.7 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 10.8;Endothelial cells: 8.7;Hepatic stellate cells: 30.7;Macrophages: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 9.5;U-2197: 6.8;U-937: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 3.8 8.7 1.3 1.6 1.1 1.0 1.9 1.8 1.3 5.4 1.3 2.3 0.8 5.2 0.4 1.7 3.3 1.0 5.0 1.1 1.1 6.3 6.1 4.4 1.0 1.7 1.3 2.0 0.9 1.2 1.0 3.2 1.5 2.5 0.4 0.5 0.6 1.4 1.4 1.1 3.2 1.8 1.1 7.0 2.5 0.6 1.4 0.3 2.6 0.6 0.3 2.6 3.6 2.1 0.2 0.2 0.3 3.4 0.7 1.7 0.5 2.4 0.6 1.8 1.4 0.1 0.3 0.1 3.5 1.0 1.8 0.2 0.7 0.0 0.7 0.2 0.8 2.3 9.5 0.2 0.9 0.2 4.1 0.8 0.0 2.4 0.0 1.4 0.7 0.1 3.8 0.4 0.3 0.1 0.2 1.2 0.3 0.1 2.1 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.4 0.1 0.3 1.5 4.2 2.1 3.8 0.8 6.8 2.3 0.2 0.3 0.2 3.1 6.1 0.9 3.7 0.4 0.4 2.5 0.2 0.3 2.0 0.7 2.2 0.1 11.1 4.3 9.4 4.1 3.3 0.3 0.3 0.2 4.0 1.3 1.1 1.8 1.3 1.1 1.1 1.7 1.3 1.5 1.1 1.4 2.1 10.8 0.0 0.0 0.0 2.6 0.5 0.1 0.0 0.0 0.3 0.1 0.1 1.3 0.0 0.0 1.8 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.6 8.7 0.0 0.0 0.3 0.0 0.2 2.3 0.0 0.1 0.0 0.2 30.7 0.6 0.9 0.0 0.9 0.0 0.0 1.0 0.3 0.0 0.3 19.2 1.8 1.9 0.3 0.5 1.0 0.5 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 2.5 0.4 1.9 0.1 0.6 0.1 0.8 0.4 0.1 0.0 TCAF1 "FAM115A, KIAA0738" ENSG00000198420 "TRPM8 channel associated factor 1" Q9Y4C2 7 143851375-143902198 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 251.7;Syncytiotrophoblasts: 521.5;Theca cells: 377.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011732 Approved Approved "Nuclear bodies,Vesicles,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 28: Placenta - Pregnancy" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 52: Non-specific - Transcription" "Cell Junctions" "Nuclear bodies, Vesicles" "HPA011732: AB_2668526" "unprognostic (1.57e-1)" "unprognostic (7.28e-2)" "unprognostic (2.61e-1)" "unprognostic (3.11e-1)" "unprognostic (2.73e-1)" "unprognostic (7.00e-2)" "unprognostic (5.70e-3)" "unprognostic (3.07e-2)" "unprognostic (4.93e-2)" "prognostic favorable (5.93e-4)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (3.95e-3)" "unprognostic (6.45e-2)" "unprognostic (1.34e-1)" "unprognostic (1.55e-2)" "unprognostic (1.89e-1)" 29.0 46.5 22.7 12.9 51.4 4.7 21.7 15.1 30.3 27.5 2.7 18.8 12.2 32.2 15.2 15.1 22.2 19.3 23.7 29.4 42.7 14.8 29.3 19.0 8.4 15.4 13.4 39.9 19.4 35.1 27.2 81.1 19.8 36.2 20.3 28.0 15.8 19.8 17.5 16.9 15.8 30.6 11.5 11.7 21.7 9.4 31.0 17.1 26.8 55.7 9.0 14.8 13.4 20.1 47.2 29.0 90.1 93.7 57.9 55.7 55.1 54.3 64.9 42.4 56.3 60.5 33.0 0.2 25.2 63.3 54.5 29.7 34.8 35.7 46.5 25.7 26.0 25.7 15.7 54.0 39.7 0.3 16.2 58.2 31.5 50.0 18.4 66.8 53.4 32.2 43.2 4.5 83.2 70.7 42.3 15.9 27.6 52.0 17.4 26.0 60.7 6.2 33.7 37.5 25.6 153.1 55.5 34.2 25.7 63.7 51.5 4.0 48.8 44.6 28.5 42.2 32.7 14.0 19.2 0.4 81.9 7.6 62.3 0.4 1.5 0.9 4.7 1.8 3.3 1.6 2.8 3.1 2.9 1.6 2.4 3.0 0.4 4.4 3.1 1.4 2.3 2.5 22.7 51.4 15.1 30.3 29.4 42.7 15.4 13.4 19.8 11.5 31.0 20.1 36.3 44.8 37.1 30.3 7.3 0.0 15.0 0.0 16.5 47.7 29.4 38.6 43.0 31.5 14.9 3.7 25.0 251.7 15.2 18.7 0.0 30.9 2.4 27.6 62.7 35.1 19.4 22.1 71.2 35.6 43.7 54.6 20.9 40.5 7.6 167.5 34.6 83.6 32.9 30.3 63.1 29.3 0.0 10.5 0.0 3.5 53.1 12.2 0.0 29.0 10.8 27.5 20.6 57.3 43.7 49.9 15.4 56.4 8.4 27.3 20.1 8.9 8.0 26.7 13.1 72.1 53.3 13.3 11.7 14.1 0.0 521.5 10.4 377.5 23.5 24.3 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TCAF2C ENSG00000283528 "TRPM8 channel associated factor 2C" 7 143639230-143647646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 35: T-regs - Unknown function" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 0.5 0.3 0.8 0.4 0.0 0.3 0.5 0.5 0.0 0.7 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TCHP "MGC10854, TpMs" ENSG00000139437 "Trichoplein keratin filament binding" Q9BT92 12 109900264-109983841 "Predicted intracellular proteins" "Apoptosis, Cilium biogenesis/degradation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA038638, HPA061543" Supported Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Centrosome, Cytosol" "HPA038638: AB_10670785, HPA061543: AB_2684556" "unprognostic (2.21e-1)" "unprognostic (1.51e-2)" "unprognostic (2.58e-1)" "unprognostic (1.04e-1)" "unprognostic (2.58e-1)" "unprognostic (4.82e-2)" "unprognostic (1.42e-2)" "unprognostic (7.94e-2)" "unprognostic (1.59e-2)" "unprognostic (9.75e-2)" "unprognostic (1.15e-3)" "unprognostic (4.63e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.52e-4)" "unprognostic (1.35e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" 6.5 7.3 9.7 8.9 10.6 6.8 6.6 10.9 11.3 10.1 8.1 10.4 7.3 9.1 7.5 15.4 7.6 5.9 8.1 9.4 10.5 7.8 5.6 7.3 11.7 10.4 10.5 8.9 10.9 7.4 6.4 7.6 10.5 8.6 6.8 9.2 10.5 7.9 9.1 27.4 8.2 7.6 9.2 11.8 8.2 9.3 10.7 10.4 8.6 7.0 11.6 9.3 13.8 11.0 27.6 24.0 12.7 15.3 11.0 11.9 17.3 25.6 13.4 21.8 12.1 15.2 9.4 38.2 7.2 14.9 11.8 22.5 14.0 16.0 19.5 20.7 13.8 27.6 15.3 15.0 13.3 38.0 20.4 9.8 19.1 22.9 17.1 13.7 19.7 23.8 30.5 7.5 18.2 18.9 35.0 38.4 15.3 6.6 24.2 31.7 24.9 32.4 9.9 24.2 18.8 19.8 18.5 19.8 18.2 9.0 17.9 27.2 21.8 22.2 15.5 14.3 32.7 21.8 29.5 27.0 23.5 31.0 23.7 0.0 2.7 2.3 3.6 1.7 2.6 2.0 3.2 4.5 2.1 1.3 3.2 2.5 2.7 5.9 3.7 1.5 4.7 3.1 9.7 10.6 10.9 11.3 9.4 10.5 10.4 10.5 10.5 9.2 10.7 11.0 11.7 19.2 21.4 18.9 10.4 9.8 7.7 9.5 8.0 28.9 11.3 11.4 13.2 17.2 12.0 7.3 18.8 11.2 14.3 12.8 9.8 20.7 32.5 23.0 19.1 15.2 14.8 15.4 8.3 15.1 8.4 11.4 10.2 13.2 13.3 15.7 7.9 7.4 11.6 25.2 12.3 10.7 10.2 13.0 7.8 47.6 11.1 11.4 7.2 1.9 14.3 13.9 35.0 10.1 19.4 18.8 14.4 27.8 15.0 9.1 14.2 6.6 33.6 24.0 13.1 19.6 12.6 25.1 33.2 14.8 24.7 7.0 15.9 30.9 12.2 30.7 TCIM "C8orf4, hTC-1, TC-1, TC1" ENSG00000176907 "Transcriptional and immune response regulator" Q9NR00 8 40153482-40155310 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 209.5;Alveolar cells type 2: 882.5;Collecting duct cells: 200.5;Distal tubular cells: 193.7;Ductal cells: 331.6;Glandular and luminal cells: 397.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 48.5;AF22: 134.4;BJ: 51.5;BJ hTERT+: 134.4;EFO-21: 87.5;HeLa: 94.8;RPTEC TERT1: 67.2;SuSa: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027188 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Plasma membrane, Cytosol" "HPA027188: AB_10601150" "unprognostic (8.88e-2)" "unprognostic (2.76e-2)" "unprognostic (7.89e-3)" "unprognostic (7.95e-2)" "unprognostic (7.33e-3)" "unprognostic (1.87e-3)" "unprognostic (2.11e-1)" "unprognostic (2.32e-1)" "unprognostic (2.93e-2)" "unprognostic (8.15e-2)" "unprognostic (6.23e-2)" "unprognostic (8.19e-2)" "unprognostic (2.54e-2)" "unprognostic (5.32e-3)" "unprognostic (1.39e-1)" "unprognostic (9.13e-3)" "unprognostic (4.48e-2)" 91.5 24.2 6.2 42.9 7.4 0.0 64.0 6.0 10.8 134.1 10.6 68.7 30.9 67.7 18.3 22.3 20.3 105.2 130.8 6.5 6.5 252.6 210.0 165.4 18.0 6.5 6.6 44.6 51.5 70.3 18.9 165.1 6.9 67.7 71.1 4.5 176.0 28.3 37.7 13.2 101.4 43.5 6.9 83.3 56.1 4.8 8.6 3.8 53.9 47.9 4.1 255.3 26.2 7.8 0.0 48.5 134.4 0.0 0.0 0.0 0.3 51.5 134.4 0.2 0.6 0.7 0.0 0.0 87.5 1.0 0.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 94.8 21.4 0.3 0.0 0.1 0.7 0.0 0.0 0.0 0.0 12.2 0.0 0.0 0.0 0.3 1.0 0.0 0.5 0.6 0.0 0.0 0.1 0.0 0.2 67.2 0.1 0.1 0.2 0.2 4.6 0.0 50.4 0.0 0.0 43.6 0.0 1.2 0.4 0.8 1.2 1.7 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 7.4 6.0 10.8 6.5 6.5 6.5 6.6 6.9 6.9 8.6 7.8 209.5 99.3 882.5 0.0 2.8 0.0 0.0 0.0 0.0 0.0 124.9 62.0 0.0 0.0 77.4 200.5 0.0 12.3 1.5 0.0 193.7 331.6 0.0 152.6 90.7 103.2 0.0 0.0 0.0 111.2 26.5 13.5 0.0 397.4 26.5 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 4.6 0.0 0.0 0.0 0.0 102.4 0.0 0.0 0.1 0.0 0.0 2.5 8.7 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 4.5 8.1 22.7 0.0 0.0 TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965822-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "HPA052263: AB_2681777" "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavorable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" 10.8 13.6 5.8 15.9 6.4 18.1 12.0 6.7 7.2 10.0 7.2 13.2 11.4 11.6 9.5 17.8 8.7 12.2 9.8 6.3 6.0 8.5 12.1 9.6 21.0 5.3 5.5 9.7 9.5 10.4 9.5 17.5 5.5 9.6 15.6 10.5 9.2 7.3 9.5 12.8 13.4 10.9 4.6 11.9 11.2 4.9 5.5 25.7 10.6 9.6 19.1 17.1 11.2 7.3 42.6 21.4 64.4 37.2 15.5 13.7 69.4 32.4 12.3 42.6 23.6 39.1 18.2 99.4 18.8 26.3 6.9 27.9 76.8 36.5 32.6 42.8 66.8 76.4 31.8 17.5 14.8 95.4 55.8 16.3 48.0 31.5 24.6 25.9 42.3 58.4 91.1 15.8 20.6 45.2 107.6 53.6 76.7 33.0 34.0 107.9 32.8 35.0 46.4 61.4 84.2 58.0 38.9 42.7 28.4 37.7 70.7 52.2 26.5 13.3 21.5 14.3 37.5 34.5 49.5 81.8 14.2 52.0 25.3 55.0 53.0 45.8 28.9 39.2 22.0 43.4 28.1 24.3 34.6 39.8 28.5 25.5 35.5 33.6 40.1 92.5 30.5 17.6 5.8 6.4 6.7 7.2 6.3 6.0 5.3 5.5 5.5 4.6 5.5 7.3 35.4 38.5 23.8 12.1 54.6 79.0 49.1 63.0 38.7 51.3 61.2 54.9 25.9 37.1 49.4 33.1 27.1 66.7 68.7 35.2 37.2 68.6 6.2 44.7 44.7 45.2 81.7 69.4 30.3 53.9 82.6 38.5 47.4 45.7 40.4 27.0 39.3 36.4 44.1 35.3 30.0 55.7 87.5 44.8 42.1 3.8 27.4 42.4 16.0 23.4 41.1 24.4 43.3 20.6 20.9 79.7 39.0 30.1 52.6 52.4 28.4 30.5 40.8 39.0 46.0 37.4 38.0 11.0 23.1 52.8 102.9 156.7 49.8 25.0 42.6 61.8 TDO2 "TDO, TPH2" ENSG00000151790 "Tryptophan 2,3-dioxygenase" P48775 4 155854738-155920406 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "liver: 797.8" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1174.2" "Cancer enriched" "Detected in many" 18 "liver cancer: 35.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 9.6;HDLM-2: 22.0;U-87 MG: 11.3" "Group enriched" "Detected in some" 7 "cerebellum: 6.3;hippocampal formation: 5.3;white matter: 1.9" "Low region specificity" "Detected in all" HPA039611 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA039611: " "unprognostic (1.10e-1)" "unprognostic (3.00e-3)" "unprognostic (3.84e-2)" "unprognostic (1.95e-1)" "unprognostic (7.06e-2)" "unprognostic (3.50e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (4.68e-8)" "unprognostic (7.99e-2)" "unprognostic (9.29e-3)" "unprognostic (1.28e-1)" "unprognostic (1.95e-2)" 0.3 1.6 0.3 16.8 0.5 0.0 0.1 0.2 1.2 0.2 0.2 1.2 3.5 0.4 0.6 0.7 0.3 1.9 0.0 0.5 0.3 0.6 797.8 3.2 3.1 0.2 1.1 0.1 0.3 0.1 4.0 0.6 0.2 0.2 1.4 0.0 0.4 0.2 0.2 0.0 5.9 2.5 0.3 1.9 1.6 0.4 0.3 0.2 0.2 0.0 2.6 7.6 0.1 0.7 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.2 0.0 0.1 0.0 0.0 22.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 1.1 0.0 0.0 0.0 0.9 0.0 0.0 0.1 3.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 1.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.5 0.0 3.4 0.0 0.0 11.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.2 1.2 0.5 0.3 0.2 1.1 0.2 0.3 0.3 0.7 0.8 0.0 0.0 0.7 2.7 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.6 158.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.5 0.1 1.1 2.4 0.0 32.0 4.1 0.0 0.0 1.7 3.6 0.1 0.0 0.0 29.6 1174.2 0.9 0.0 0.4 0.0 0.0 31.7 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.6 0.0 11.3 0.4 1.1 0.0 0.0 0.3 2.3 0.3 0.0 0.1 TDP1 "FLJ11090, SCAN1" ENSG00000042088 "Tyrosyl-DNA phosphodiesterase 1" Q9NUW8 14 89954939-90044764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071317 Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Plasma membrane" "HPA071317: AB_2686388" "unprognostic (5.60e-3)" "unprognostic (3.53e-1)" "unprognostic (7.03e-3)" "unprognostic (1.34e-1)" "unprognostic (7.45e-2)" "unprognostic (7.22e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (2.61e-1)" "unprognostic (1.46e-2)" "unprognostic (5.84e-3)" "unprognostic (2.51e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.91e-2)" "unprognostic (1.26e-1)" 5.5 3.9 4.8 11.8 4.5 13.9 8.9 6.6 4.9 6.6 7.1 7.8 6.5 5.9 5.8 8.2 9.2 6.6 2.6 4.1 5.3 7.0 6.5 4.7 19.0 3.8 3.6 6.4 4.8 5.1 4.6 8.2 3.9 5.0 10.1 4.9 5.5 4.3 2.1 6.4 7.0 6.3 2.8 10.6 7.9 22.3 4.6 28.3 4.9 1.7 23.7 8.1 5.0 4.2 33.8 18.6 40.9 37.5 10.1 14.0 32.7 31.7 25.9 38.4 34.6 13.6 35.5 42.9 23.3 21.7 12.9 33.9 18.2 29.5 55.2 44.1 19.6 43.9 16.7 16.6 8.7 73.2 24.1 10.1 12.9 26.9 24.9 21.9 49.5 57.3 30.6 43.5 45.9 35.0 56.3 39.2 10.0 39.8 43.7 42.3 77.3 34.0 24.6 27.3 30.7 20.9 26.9 77.6 10.1 27.0 31.0 30.8 39.9 16.5 15.7 23.0 28.7 31.8 60.4 52.3 35.5 32.3 24.6 28.7 8.9 15.1 18.8 14.6 18.3 21.1 19.8 20.8 14.2 20.0 21.7 23.1 5.7 23.8 14.1 15.0 32.2 14.8 4.8 4.5 6.6 4.9 4.1 5.3 3.8 3.6 3.9 2.8 4.6 4.2 2.9 0.0 1.1 4.2 15.2 4.7 4.9 7.4 4.0 3.0 6.4 7.1 1.4 1.5 5.0 14.7 8.4 11.4 14.6 3.8 5.9 9.2 123.5 13.2 6.1 3.6 3.6 12.8 13.4 5.6 14.9 4.3 7.7 9.2 2.5 8.9 3.9 4.2 8.8 3.3 13.9 4.9 0.0 6.8 10.2 36.7 2.8 7.8 1.8 1.9 8.0 1.5 8.2 8.0 24.2 6.4 4.8 3.0 16.9 5.7 2.9 7.8 11.0 2.7 0.0 3.4 5.4 33.7 22.8 8.7 4.5 10.1 15.0 10.3 7.9 4.0 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 13.9;Glandular and luminal cells: 25.1;granulocytes: 19.6;Plasma cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 20.7;eosinophil: 13.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "HEL: 13.5;HMC-1: 20.3;U-266/70: 20.3;U-266/84: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 0.9 1.7 0.1 2.1 0.2 6.1 1.4 0.1 0.4 1.2 1.0 1.3 1.6 1.1 4.2 3.4 1.9 1.1 1.3 0.0 0.4 1.1 2.5 2.0 3.1 1.1 0.3 0.4 0.8 1.2 0.6 1.1 1.1 0.5 1.3 1.8 2.3 1.0 0.6 3.6 1.5 0.8 0.3 1.7 1.1 1.2 0.7 2.0 1.3 0.5 3.3 1.0 1.6 0.2 3.0 0.8 0.0 0.0 0.0 0.0 0.1 0.5 2.2 1.3 2.7 0.0 2.2 1.9 2.0 0.0 0.1 0.6 1.1 0.0 1.8 0.1 0.8 13.5 1.0 0.1 0.0 2.2 20.3 0.0 0.3 1.7 0.0 1.4 0.0 0.6 7.5 0.5 4.1 1.0 1.3 4.9 0.4 1.4 0.8 3.1 2.7 0.0 3.4 0.9 0.0 0.2 0.6 0.3 0.5 1.1 0.7 4.2 0.0 0.0 0.0 2.8 0.0 20.3 15.4 2.6 0.0 3.0 0.1 20.7 0.6 13.3 0.1 0.7 0.3 1.0 0.2 0.5 1.5 0.7 0.5 0.5 0.5 3.6 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.0 0.4 1.1 0.3 1.1 0.3 0.7 0.2 0.6 6.4 6.8 0.7 6.8 2.5 1.7 0.2 2.8 0.9 1.7 1.1 1.8 7.2 2.6 0.0 0.0 1.5 3.3 2.1 0.0 1.7 6.4 13.9 1.5 1.2 3.0 12.6 6.7 1.1 0.1 0.8 0.0 25.1 19.6 0.7 0.0 2.9 4.9 0.0 1.6 1.4 4.1 4.6 1.8 2.6 0.0 5.9 1.8 10.3 1.7 6.6 0.0 0.5 0.2 1.0 0.6 0.4 15.4 1.3 3.0 2.0 0.2 3.1 6.6 1.8 0.8 0.7 1.4 9.8 3.0 0.8 3.4 0.3 2.1 1.6 TEDC2 "C16orf59, FLJ13909" ENSG00000162062 "Tubulin epsilon and delta complex 2" Q7L2K0 16 2460086-2464963 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 4.0;testis: 5.0" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 12.8;Extravillous trophoblasts: 12.5;Granulosa cells: 6.7;Hofbauer cells: 4.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051394, HPA055389" Approved Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 14: REH - Unknown function" "Cluster 12: Non-specific - Cell cycle regulation" "Nucleoplasm, Cell Junctions" "HPA051394: AB_2681465, HPA055389: AB_2732595" "unprognostic (3.23e-1)" "unprognostic (1.03e-2)" "unprognostic (2.14e-2)" "unprognostic (7.46e-3)" "unprognostic (1.27e-1)" "unprognostic (1.38e-3)" "prognostic unfavorable (2.43e-5)" "prognostic unfavorable (7.58e-4)" "unprognostic (4.04e-3)" "unprognostic (8.85e-2)" "unprognostic (3.74e-2)" "unprognostic (3.72e-2)" "unprognostic (1.16e-4)" "unprognostic (1.28e-3)" "unprognostic (1.56e-1)" "unprognostic (1.24e-2)" "unprognostic (1.03e-1)" 0.3 0.8 0.8 1.7 0.9 4.0 0.4 0.4 1.4 0.7 0.2 1.0 1.5 0.4 0.0 2.3 0.3 0.1 0.8 0.8 0.6 0.6 0.8 0.5 2.2 0.7 0.6 0.4 0.6 0.2 0.8 0.9 0.8 0.6 0.7 0.2 0.6 0.2 0.3 0.9 1.4 0.3 0.4 1.2 0.8 5.0 0.9 2.2 0.4 0.0 1.4 0.4 0.8 0.6 10.2 31.3 17.7 20.8 0.3 1.2 17.7 7.9 4.7 12.5 12.1 21.9 8.2 14.0 12.6 3.4 6.8 15.3 12.9 8.0 3.0 15.6 17.4 12.7 23.2 22.9 0.4 12.3 16.3 1.1 1.0 11.0 3.0 1.0 5.8 22.8 21.9 5.2 4.4 19.7 21.6 23.2 39.2 9.7 11.5 52.0 15.1 31.3 2.7 4.4 16.6 27.2 9.1 9.5 7.1 4.7 14.0 14.2 2.2 13.2 19.2 12.8 18.2 11.4 20.1 28.3 6.7 12.3 18.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.2 0.1 0.2 0.0 0.0 0.2 0.2 0.4 0.1 0.8 0.9 0.4 1.4 0.8 0.6 0.7 0.6 0.8 0.4 0.9 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 1.9 0.0 0.0 0.0 0.0 0.0 12.8 0.5 0.0 1.9 2.9 0.0 1.2 1.1 0.6 0.0 0.0 0.0 1.3 12.5 1.7 0.0 1.0 0.0 6.7 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.7 1.5 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 2.9 0.4 2.7 0.0 0.0 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TEKT3 FLJ32828 ENSG00000125409 "Tektin 3" Q9BXF9 17 15303811-15341632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 31.0" "Group enriched" "Detected in some" 10 "Early spermatids: 413.1;Late spermatids: 408.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.7" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SuSa: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027293, HPA044354, HPA073565" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Nucleoplasm "HPA027293: , HPA044354: AB_10962623, HPA073565: " "unprognostic (1.85e-1)" "unprognostic (6.64e-3)" "unprognostic (9.73e-2)" "unprognostic (5.38e-4)" "unprognostic (4.59e-2)" "unprognostic (3.09e-2)" "unprognostic (9.07e-2)" "unprognostic (8.63e-3)" "unprognostic (4.91e-2)" "unprognostic (1.23e-1)" "unprognostic (9.67e-4)" "unprognostic (1.29e-1)" "unprognostic (1.09e-4)" "unprognostic (1.69e-2)" "unprognostic (3.00e-1)" "unprognostic (2.90e-3)" "unprognostic (7.85e-2)" 0.3 0.2 0.7 0.3 0.6 0.1 0.5 1.4 0.9 1.2 0.6 0.3 0.3 0.5 0.6 0.1 4.9 0.4 0.2 0.4 0.4 0.3 0.2 0.8 0.1 0.9 1.0 0.9 0.7 0.2 1.0 0.3 0.5 0.4 0.2 0.6 0.5 0.1 0.1 0.7 0.4 0.2 0.5 0.2 0.2 31.0 0.4 0.1 0.7 0.0 0.1 0.2 0.4 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.1 0.1 1.5 0.0 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.7 0.6 1.4 0.9 0.4 0.4 0.9 1.0 0.5 0.5 0.4 1.1 0.7 3.2 0.5 0.7 0.1 0.3 0.1 0.7 0.0 0.7 0.5 0.5 0.7 1.5 4.7 0.0 0.0 0.3 0.2 0.5 0.0 0.1 413.1 16.3 1.7 0.7 1.8 0.0 1.2 0.0 0.5 3.9 0.0 0.5 0.0 0.7 0.4 0.1 3.8 0.0 1.1 0.0 0.0 0.0 1.4 408.9 11.1 0.3 0.0 1.0 0.0 1.7 0.0 2.0 0.8 0.0 0.1 6.4 0.0 0.2 0.7 0.1 39.1 0.2 6.6 3.2 1.4 25.9 2.6 0.0 0.1 0.0 0.1 3.4 0.0 0.2 TENT4B "PAPD5, TRF4-2, TUT3" ENSG00000121274 "Terminal nucleotidyltransferase 4B" Q8NDF8 16 50152911-50235310 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, mRNA processing, rRNA processing" "DNA-binding, DNA-directed DNA polymerase, Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 82.8;Endometrial ciliated cells: 44.3;Glandular and luminal cells: 31.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042968, HPA048225" Uncertain Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Nucleoli, Plasma membrane" "HPA042968: AB_2678244, HPA048225: AB_2680319" "unprognostic (1.05e-2)" "unprognostic (4.09e-2)" "unprognostic (1.77e-2)" "unprognostic (1.63e-1)" "unprognostic (3.27e-1)" "unprognostic (2.91e-2)" "unprognostic (4.33e-2)" "unprognostic (2.46e-1)" "unprognostic (7.83e-2)" "unprognostic (1.30e-1)" "unprognostic (1.30e-1)" "unprognostic (3.30e-2)" "prognostic favorable (1.85e-4)" "unprognostic (4.24e-2)" "unprognostic (1.06e-1)" "unprognostic (1.83e-1)" "unprognostic (7.00e-2)" 6.1 6.4 2.4 1.7 2.3 7.1 4.6 3.9 2.6 7.3 3.0 6.9 4.6 6.9 2.3 5.4 6.5 2.0 3.7 2.7 3.0 4.2 8.9 5.0 2.3 2.2 2.4 6.8 4.3 3.9 4.8 2.8 2.2 5.3 1.9 1.4 4.7 1.7 5.4 5.5 5.9 2.5 2.2 4.6 5.5 5.7 3.1 1.7 4.7 2.1 1.9 7.2 6.4 2.7 5.5 1.9 0.6 3.3 3.8 2.0 4.3 3.9 2.3 3.5 1.6 3.4 2.3 6.5 5.6 2.7 1.4 3.6 3.9 2.0 3.1 3.8 4.5 3.6 1.6 5.4 3.8 2.4 4.9 1.9 2.6 2.3 3.3 2.3 1.8 2.1 4.2 1.5 4.1 1.5 3.5 4.6 4.2 1.5 4.5 4.9 4.8 6.9 1.7 0.5 4.0 2.2 4.9 2.7 2.3 1.5 1.5 0.9 3.0 2.1 4.1 4.0 1.9 4.9 3.7 6.9 1.7 2.7 2.7 0.0 0.4 0.0 0.4 0.2 0.1 0.3 0.2 0.5 0.2 0.2 0.3 0.5 0.7 0.2 0.2 0.4 0.1 0.1 2.4 2.3 3.9 2.6 2.7 3.0 2.2 2.4 2.2 2.2 3.1 2.7 17.9 0.0 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.0 17.8 16.3 0.0 0.0 0.0 14.7 0.0 18.1 82.8 0.0 3.9 10.9 0.0 44.3 24.4 6.1 0.0 0.0 0.0 14.9 11.5 6.7 0.0 31.5 0.0 13.5 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.7 0.0 0.0 3.6 0.0 0.0 0.0 0.0 15.2 0.0 0.0 22.0 0.0 0.0 20.2 0.0 0.0 0.0 0.0 14.0 0.0 0.0 0.0 0.0 18.3 14.9 17.3 0.0 0.0 TERB1 "CCDC79, FLJ35894" ENSG00000249961 "Telomere repeat binding bouquet formation protein 1" Q8NA31 16 66754640-66801620 "Predicted intracellular proteins" Meiosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "testis: 12.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "basophil: 1.9" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA079436 Supported "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Cell Junctions, Cytosol" "HPA079436: " "unprognostic (2.15e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (2.29e-1)" "unprognostic (3.91e-2)" "unprognostic (9.75e-2)" "unprognostic (5.79e-2)" "unprognostic (1.03e-1)" "unprognostic (7.57e-5)" "unprognostic (6.49e-2)" "unprognostic (3.23e-3)" "unprognostic (2.88e-2)" "unprognostic (6.81e-6)" "unprognostic (1.66e-1)" "unprognostic (2.56e-1)" "unprognostic (2.34e-1)" "unprognostic (6.14e-3)" 0.1 0.3 0.7 0.2 0.4 1.5 0.0 1.6 1.0 0.0 1.5 0.1 0.4 0.2 0.1 0.2 0.1 0.1 0.0 0.4 0.6 0.1 0.1 0.2 0.3 1.3 0.4 0.1 0.0 0.0 0.0 0.1 0.9 0.1 0.1 0.4 0.3 0.0 0.1 0.7 0.1 0.0 0.1 0.2 0.0 12.6 0.8 0.0 0.4 0.0 0.1 0.0 0.0 1.6 0.2 0.6 0.2 0.1 0.4 0.0 0.0 0.1 0.0 0.2 0.2 0.8 0.4 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.6 0.1 0.7 0.4 0.0 0.0 0.4 0.1 0.3 0.1 0.0 0.0 0.1 0.2 0.1 0.4 0.0 0.4 0.2 0.4 0.1 0.0 0.0 0.2 0.1 0.5 0.0 0.6 0.3 0.3 0.1 0.2 0.1 0.4 0.0 0.2 0.0 0.4 0.2 0.5 0.2 0.3 0.2 0.6 0.3 0.3 0.1 1.9 0.2 0.1 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.4 0.1 0.2 0.8 0.4 0.1 1.1 0.1 0.3 0.7 0.4 1.6 1.0 0.4 0.6 1.3 0.4 0.9 0.1 0.8 1.6 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 TES "DKFZP586B2022, TESS-2, TESTIN" ENSG00000135269 "Testin LIM domain protein" Q9UGI8 7 116210506-116258783 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 197.1" "Cell type enhanced" "Detected in many" "Early spermatids: 386.6;Glandular and luminal cells: 283.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "EFO-21: 230.0;hTCEpi: 263.6;SK-BR-3: 267.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA015269, HPA018123" Approved Supported "Plasma membrane,Cell Junctions,Focal adhesion sites,Cytosol" NA NA 34000 "Cluster 2: Granulocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Focal adhesion sites, Cytosol" "Plasma membrane, Cell Junctions" "HPA015269: AB_1857899, HPA018123: AB_1857900" "unprognostic (9.81e-2)" "unprognostic (5.53e-3)" "unprognostic (4.79e-2)" "unprognostic (1.31e-1)" "unprognostic (4.01e-1)" "unprognostic (6.08e-3)" "unprognostic (1.84e-3)" "unprognostic (4.81e-3)" "unprognostic (8.81e-3)" "unprognostic (6.19e-3)" "prognostic unfavorable (1.20e-5)" "unprognostic (1.60e-2)" "prognostic favorable (8.71e-5)" "unprognostic (1.50e-1)" "unprognostic (5.47e-2)" "unprognostic (2.36e-2)" "unprognostic (3.86e-1)" 29.3 7.2 2.7 54.4 2.7 44.1 32.2 3.4 3.6 29.0 10.0 134.7 41.1 105.9 21.7 58.2 45.2 37.4 14.7 2.3 2.9 19.3 10.1 41.0 49.6 6.4 3.5 7.3 20.8 15.3 5.7 25.6 3.4 55.2 69.0 13.4 34.2 197.1 5.1 23.2 47.5 147.6 3.2 30.0 52.1 39.9 4.3 33.5 66.4 8.9 51.3 87.1 41.1 3.0 115.9 24.0 27.0 0.2 11.7 29.7 62.3 58.9 28.9 10.9 10.6 60.4 126.2 0.0 230.0 41.7 1.3 116.9 14.4 87.3 26.4 57.3 46.0 11.5 53.1 30.5 69.9 53.6 0.2 66.4 263.6 37.7 95.0 74.9 31.1 0.0 11.9 39.5 3.0 24.4 0.2 0.7 17.8 134.0 67.4 0.2 0.4 46.0 110.9 44.0 12.4 113.4 85.5 267.1 68.2 77.6 0.3 21.5 52.3 0.6 1.5 86.2 0.7 92.6 48.9 1.3 7.4 27.2 89.3 274.7 79.2 221.5 150.2 132.1 144.7 104.6 113.4 137.6 86.9 95.5 111.0 127.6 41.6 205.1 170.5 20.7 130.4 162.8 2.7 2.7 3.4 3.6 2.3 2.9 6.4 3.5 3.4 3.2 4.3 3.0 40.8 243.6 47.0 0.0 60.4 200.4 196.2 64.8 60.3 2.2 62.2 57.0 16.1 47.1 81.7 36.8 12.5 23.2 121.3 140.8 21.5 110.7 386.6 176.7 29.9 49.0 50.6 17.7 0.1 112.3 78.1 23.6 84.1 283.9 18.9 54.1 25.7 11.9 15.4 1.7 0.1 100.7 34.6 58.0 119.0 112.5 1.8 78.0 28.4 10.3 77.6 24.7 201.8 0.0 0.3 196.8 112.1 0.4 76.3 102.4 65.3 13.6 68.1 13.9 6.6 9.0 42.3 19.1 10.6 55.9 122.7 29.1 79.2 8.8 79.7 135.9 TEX14 CT113 ENSG00000121101 "Testis expressed 14, intercellular bridge forming factor" Q8IWB6 17 58556678-58692055 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "testis: 27.0" "Group enriched" "Detected in many" 4 "Early spermatids: 23.3;Spermatocytes: 56.4;Spermatogonia: 16.2" "Cancer enhanced" "Detected in some" "breast cancer: 0.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 6.3;Karpas-707: 7.9;MCF7: 3.3" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA030620, HPA077020" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 2: Karpas-707 - Immune response" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Vesicles, Plasma membrane" "HPA030620: AB_10601598, HPA077020: AB_2732327" "unprognostic (1.21e-2)" "unprognostic (2.12e-1)" "unprognostic (2.06e-1)" "unprognostic (9.49e-2)" "unprognostic (2.48e-1)" "unprognostic (1.23e-2)" "unprognostic (1.10e-1)" "unprognostic (6.17e-2)" "unprognostic (2.07e-2)" "unprognostic (1.61e-3)" "unprognostic (2.67e-2)" "unprognostic (8.10e-2)" "unprognostic (1.76e-9)" "unprognostic (1.77e-1)" "unprognostic (2.54e-1)" "unprognostic (5.00e-3)" "unprognostic (5.88e-2)" 0.1 0.1 0.5 0.1 0.6 1.7 0.2 1.1 0.6 0.1 0.2 0.1 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.5 0.4 0.2 0.2 0.1 0.5 0.5 0.3 0.1 0.0 0.2 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.0 0.1 0.1 0.0 0.5 0.2 0.1 27.0 0.5 0.0 0.0 0.0 0.1 0.1 0.0 0.8 0.0 0.0 0.1 1.7 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.2 0.0 0.1 6.3 0.9 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.1 7.9 0.0 3.3 0.3 0.0 0.4 0.1 0.1 0.3 0.2 1.2 0.0 0.1 0.9 0.1 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 1.4 0.3 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 1.1 0.6 0.4 0.5 0.5 0.5 0.5 0.5 0.5 0.8 4.4 0.0 0.0 2.9 5.7 0.9 1.8 0.7 2.8 0.6 4.7 7.2 1.3 5.7 1.5 1.8 0.0 1.6 0.7 0.1 0.0 0.0 23.3 0.4 0.2 1.5 0.0 0.0 2.2 0.0 1.0 0.7 0.5 1.8 1.3 0.2 1.4 0.8 3.7 0.0 2.2 0.5 2.0 0.6 2.3 6.4 0.3 4.6 3.6 2.8 0.0 0.6 1.0 1.0 3.0 0.1 0.0 0.4 4.3 0.7 0.0 0.1 0.2 1.3 0.0 1.2 1.5 56.4 16.2 1.7 0.1 1.1 0.7 0.0 0.0 0.4 TEX9 ENSG00000151575 "Testis expressed 9" Q8N6V9 15 56244009-56445997 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.1;Endometrial ciliated cells: 86.2;Respiratory ciliated cells: 125.6;Spermatocytes: 74.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 4.3;memory B-cell: 14.4;naive B-cell: 11.4" "Group enriched" "Detected in many" 12 "B-cells: 14.4;granulocytes: 4.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039415 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039415: AB_10672775" "unprognostic (3.27e-1)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (4.71e-3)" "unprognostic (2.34e-1)" "unprognostic (5.13e-2)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.75e-2)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "unprognostic (8.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" 1.8 6.1 4.1 4.6 3.9 3.4 10.1 7.4 3.9 8.8 17.0 3.6 11.6 5.2 8.4 4.4 28.0 5.2 1.1 3.2 4.2 10.8 1.5 4.4 6.0 9.4 8.6 5.4 5.4 14.2 9.9 1.6 4.5 4.5 4.8 18.0 10.5 3.4 1.2 5.6 8.0 2.2 5.3 3.2 12.2 16.4 6.6 3.7 17.4 1.5 10.6 2.7 1.6 5.7 7.8 7.1 15.3 13.7 3.7 10.8 2.0 1.7 6.3 4.8 5.7 1.7 6.9 15.5 7.0 1.2 8.2 6.6 6.6 7.4 5.5 1.7 7.8 9.1 6.7 5.2 1.1 3.3 1.3 5.9 13.3 5.4 4.1 6.9 0.2 11.1 5.2 1.4 2.6 4.5 6.5 1.2 7.2 13.2 3.0 2.6 7.1 5.5 15.9 4.4 24.3 9.8 8.7 4.9 5.5 11.2 14.6 3.0 0.7 20.3 5.8 6.5 6.4 2.1 16.5 11.7 8.0 1.7 3.9 4.3 0.1 0.1 0.4 0.6 0.1 14.4 0.4 0.3 0.2 11.4 0.2 0.8 0.3 0.4 0.4 0.4 0.6 0.7 4.1 3.9 7.4 3.9 3.2 4.2 9.4 8.6 4.5 5.3 6.6 5.7 1.5 6.4 7.5 38.8 21.0 4.2 7.3 13.2 20.5 6.4 11.3 11.7 0.8 5.7 23.5 11.0 12.5 1.8 0.3 2.3 21.5 15.6 89.1 86.2 5.1 3.2 7.7 5.9 14.3 7.0 0.5 5.0 17.3 4.8 1.3 5.1 1.8 0.4 1.3 1.7 20.4 3.7 16.2 0.0 2.1 40.9 4.7 2.7 3.6 4.7 1.2 6.8 1.0 14.6 15.1 4.5 5.4 3.8 15.8 3.7 12.3 21.7 125.6 37.5 0.0 4.6 6.0 74.6 36.6 6.9 2.3 0.3 1.0 6.2 6.7 4.9 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THBS2 TSP2 ENSG00000186340 "Thrombospondin 2" P35442 6 169215780-169254050 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 86.8;Endometrial stromal cells: 71.1;Fibroblasts: 127.7;Langerhans cells: 69.8;Melanocytes: 56.9;Oligodendrocyte precursor cells: 40.7;Oligodendrocytes: 55.8;Smooth muscle cells: 33.7;Suprabasal keratinocytes: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 250.2;ASC TERT1: 200.3;BJ hTERT+: 88.6;BJ hTERT+ SV40 Large T+: 96.3;BJ hTERT+ SV40 Large T+ RasG12V: 117.8;HSkMC: 113.2;hTEC/SVTERT24-B: 127.2;U-2197: 107.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017716, HPA044304" Approved Approved "Nuclear speckles,Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 21000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles, Cytosol" "CAB017716: , HPA044304: AB_2678891" "unprognostic (2.85e-2)" "unprognostic (1.41e-1)" "unprognostic (5.87e-2)" "unprognostic (8.90e-2)" "unprognostic (3.64e-2)" "unprognostic (8.73e-2)" "unprognostic (2.93e-1)" "unprognostic (5.10e-3)" "unprognostic (1.39e-1)" "unprognostic (4.71e-2)" "unprognostic (4.00e-2)" "unprognostic (2.56e-1)" "prognostic unfavorable (3.77e-6)" "unprognostic (2.19e-3)" "unprognostic (4.38e-2)" "unprognostic (4.16e-2)" "unprognostic (2.48e-3)" 52.9 7.9 5.5 14.8 15.4 0.0 36.2 10.9 7.7 63.1 0.2 20.4 2.5 50.0 0.7 12.0 34.7 50.4 44.2 6.5 13.1 8.3 8.2 19.8 3.3 17.1 18.2 33.2 5.6 1.7 9.5 2.2 21.4 9.7 2.4 0.1 8.2 2.5 3.4 41.1 9.2 21.3 11.3 3.3 5.4 2.3 15.0 0.6 17.0 1.8 1.2 29.1 30.8 19.3 0.2 0.0 2.5 1.1 250.2 200.3 0.0 76.8 88.6 96.3 117.8 0.4 0.0 0.1 0.1 76.1 0.2 0.1 2.4 3.2 22.5 0.0 0.0 0.0 0.0 0.0 73.1 0.3 0.0 113.2 0.0 127.2 0.0 0.2 0.0 0.0 0.0 0.1 3.7 0.0 0.1 1.7 16.3 0.0 0.6 0.0 0.1 1.1 0.0 0.4 0.3 0.2 0.2 0.1 0.0 0.2 0.0 0.7 0.0 46.1 0.4 107.6 9.3 0.1 0.7 0.0 30.6 0.1 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 15.4 10.9 7.7 6.5 13.1 17.1 18.2 21.4 11.3 15.0 19.3 3.5 6.4 0.0 6.8 0.0 86.8 1.6 0.1 1.8 0.4 2.2 1.8 5.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.2 3.1 71.1 4.6 0.0 0.0 1.2 0.0 0.0 127.7 1.1 1.4 0.0 0.0 15.4 0.0 0.3 0.0 1.7 0.0 0.0 0.0 69.8 0.3 8.1 1.2 56.9 6.5 0.0 0.2 0.0 40.7 55.8 0.5 0.0 16.1 0.0 1.9 0.0 4.4 0.0 0.2 0.0 1.0 33.7 0.0 0.4 1.2 42.3 0.1 2.1 5.5 0.0 0.9 THEGL ENSG00000249693 "Theg spermatid protein like" P0DJG4 4 56530606-56603507 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.3;Late spermatids: 20.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA066627, HPA068093" Uncertain Approved "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA066627: , HPA068093: AB_2685951" "unprognostic (4.33e-2)" "unprognostic (2.88e-3)" "unprognostic (7.97e-2)" "unprognostic (1.19e-1)" "unprognostic (3.69e-2)" "unprognostic (3.26e-1)" "unprognostic (1.90e-2)" "unprognostic (6.55e-2)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (4.70e-2)" "unprognostic (4.49e-2)" "unprognostic (1.73e-1)" "unprognostic (8.41e-2)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.5 0.0 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.3 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.3 0.0 0.0 0.1 0.0 1.3 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 20.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIAM1 ENSG00000156299 "TIAM Rac1 associated GEF 1" Q13009 21 31118416-31559977 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 207.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 327.3;Microglial cells: 133.0;Oligodendrocyte precursor cells: 120.6;Oligodendrocytes: 124.6;Suprabasal keratinocytes: 143.3" "Cancer enhanced" "Detected in many" "testis cancer: 15.1" "Region enriched" "Detected in all" 4 "cerebellum: 207.9" "Group enriched" "Detected in many" 5 "classical monocyte: 17.4;intermediate monocyte: 15.3;memory CD4 T-cell: 12.5;myeloid DC: 9.6;naive CD4 T-cell: 16.2;NK-cell: 11.3;non-classical monocyte: 22.0;T-reg: 27.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 34.5;HEL: 34.7;HMC-1: 29.1;RT4: 35.5;SCLC-21H: 32.6" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 245.9" "CAB010416, HPA034853" Enhanced Supported "Nucleoplasm,Nuclear membrane,Cell Junctions,Cytokinetic bridge,Cytosol" Yes NA "Cluster 27: Non-specific - Gene expression" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "Nuclear membrane, Cytokinetic bridge, Cytosol" "CAB010416: AB_2240410, HPA034853: " "unprognostic (9.59e-2)" "unprognostic (7.44e-3)" "unprognostic (5.64e-3)" "unprognostic (1.07e-1)" "unprognostic (1.58e-1)" "unprognostic (2.81e-3)" "unprognostic (2.84e-2)" "unprognostic (3.73e-1)" "unprognostic (8.08e-2)" "unprognostic (2.70e-3)" "unprognostic (7.97e-3)" "unprognostic (9.52e-2)" "unprognostic (1.20e-3)" "unprognostic (2.38e-3)" "unprognostic (1.61e-1)" "unprognostic (1.04e-2)" "unprognostic (2.21e-1)" 7.2 12.7 40.3 6.6 35.2 2.8 5.4 207.9 49.2 17.8 12.5 5.1 1.7 9.9 3.2 39.7 11.0 4.6 5.5 51.8 26.5 5.5 7.9 5.8 11.1 26.7 33.4 3.3 2.2 0.3 12.9 4.3 36.1 9.0 3.1 8.6 5.6 3.3 0.9 27.2 5.0 11.1 27.5 5.2 2.4 10.5 37.3 18.7 1.9 0.8 11.1 12.1 18.5 28.6 2.9 1.0 21.7 1.3 0.4 4.9 34.5 0.0 0.0 2.7 0.9 0.2 3.9 7.6 1.5 0.5 4.0 5.1 2.5 4.4 4.3 0.6 12.0 34.7 0.7 0.2 0.5 0.0 29.1 2.2 1.5 14.7 5.9 2.6 0.0 11.3 0.0 10.9 11.1 14.7 5.4 0.2 7.1 5.3 9.4 7.0 6.8 0.0 3.3 35.5 32.6 8.1 1.5 11.4 1.3 7.5 4.7 0.1 0.2 3.1 12.5 0.0 1.5 12.3 9.9 6.6 7.2 2.6 24.2 1.5 17.4 0.0 0.5 15.3 3.1 0.1 12.5 2.4 9.6 0.0 16.2 1.0 1.0 11.3 22.0 0.5 27.8 5.9 40.3 35.2 207.9 49.2 51.8 26.5 26.7 33.4 36.1 27.5 37.3 28.6 3.7 3.2 2.3 21.2 1.7 83.7 65.6 3.0 22.8 8.9 4.9 1.9 1.1 1.5 11.8 0.0 2.1 10.1 8.0 1.3 0.0 1.8 11.7 25.2 2.2 31.4 5.4 2.7 43.9 0.7 29.7 11.4 2.0 28.4 24.1 2.0 35.0 5.5 8.1 74.0 327.3 0.4 10.2 22.9 73.4 11.3 34.5 26.3 10.6 133.0 37.3 35.2 4.1 120.6 124.6 1.8 11.6 58.3 3.2 30.8 0.0 0.5 1.2 4.6 6.6 0.9 2.1 1.3 9.8 60.2 143.3 10.7 16.3 82.6 1.2 106.7 TICAM1 "MGC35334, PRVTIRB, TICAM-1, TRIF" ENSG00000127666 "Toll like receptor adaptor molecule 1" Q8IUC6 19 4815932-4831712 "Disease related genes, Predicted intracellular proteins" "Antiviral defense, Apoptosis, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 45.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 156.9;Paneth cells: 146.3;Urothelial cells: 134.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA042460, HPA055421" Approved Uncertain "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 37: Intestine - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA042460: AB_10806240, HPA055421: " "unprognostic (2.09e-2)" "unprognostic (1.48e-1)" "unprognostic (1.86e-2)" "prognostic favorable (4.81e-4)" "unprognostic (3.52e-2)" "unprognostic (2.88e-2)" "unprognostic (7.60e-3)" "prognostic unfavorable (3.48e-4)" "unprognostic (9.86e-2)" "unprognostic (1.59e-1)" "unprognostic (6.16e-2)" "unprognostic (2.82e-1)" "unprognostic (4.43e-2)" "unprognostic (2.30e-2)" "unprognostic (5.02e-2)" "unprognostic (3.53e-2)" "unprognostic (6.48e-2)" 12.8 6.4 4.5 6.7 5.0 15.0 11.2 3.1 7.5 14.0 2.3 13.1 14.4 9.3 1.1 45.6 9.4 7.0 10.3 4.7 4.9 13.9 20.1 16.5 6.9 5.1 5.1 7.3 10.3 2.9 6.1 4.4 4.7 9.4 3.2 0.4 13.5 3.3 19.7 21.5 14.5 3.3 4.6 11.9 15.7 1.8 5.1 2.6 8.2 4.1 4.4 10.1 17.4 4.5 34.9 6.7 0.1 5.8 4.9 6.2 3.1 11.2 11.4 8.8 9.8 6.9 12.2 23.5 6.2 12.9 8.8 23.1 3.2 11.8 3.4 25.4 6.2 5.9 13.7 6.7 13.5 2.1 14.7 10.1 14.4 11.0 8.0 6.8 9.2 8.1 12.9 4.9 4.8 13.0 6.0 1.2 1.0 6.2 26.5 13.2 1.4 15.4 8.0 10.7 4.6 8.5 6.9 20.4 11.4 0.0 9.2 4.9 18.5 10.7 7.3 27.4 17.1 19.6 18.5 16.7 12.5 8.1 8.4 6.8 4.1 1.8 1.7 5.4 1.5 3.4 1.7 2.0 3.6 2.8 1.1 0.7 1.2 1.2 7.1 2.5 2.1 5.1 4.5 5.0 3.1 7.5 4.7 4.9 5.1 5.1 4.7 4.6 5.1 4.5 10.5 6.4 9.6 3.9 12.4 69.3 67.0 20.0 23.9 0.9 19.4 13.6 2.5 21.5 18.5 5.5 0.0 6.3 3.7 156.9 7.9 29.9 0.1 27.0 7.6 14.4 29.2 4.2 3.9 17.5 11.7 11.0 42.3 56.2 10.8 4.6 11.7 13.4 12.8 1.7 3.2 39.2 10.2 14.0 52.6 0.3 3.7 22.1 14.2 1.9 17.7 0.8 7.2 3.0 1.4 51.8 146.3 5.3 18.6 57.5 55.8 9.2 16.3 0.2 6.6 4.6 5.8 0.3 1.4 27.3 71.2 3.4 9.8 3.4 26.2 134.3 TIGD7 Sancho ENSG00000140993 "Tigger transposable element derived 7" Q6NT04 16 3298808-3305729 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041357, HPA041474" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA041357: AB_10794992, HPA041474: AB_10795696" "unprognostic (7.69e-2)" "unprognostic (3.04e-4)" "unprognostic (6.56e-3)" "unprognostic (1.18e-3)" "unprognostic (1.79e-1)" "unprognostic (4.04e-2)" "unprognostic (6.50e-3)" "unprognostic (2.44e-1)" "unprognostic (2.78e-2)" "unprognostic (9.81e-2)" "unprognostic (8.56e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-2)" "unprognostic (8.87e-2)" "unprognostic (4.04e-1)" "unprognostic (5.90e-3)" "unprognostic (3.12e-2)" 2.9 3.3 5.1 1.8 5.1 0.6 4.7 6.0 6.1 5.1 7.0 4.9 1.8 5.5 4.5 1.9 5.1 2.6 5.3 4.9 5.6 6.0 3.1 2.8 3.4 5.2 5.6 10.6 2.8 6.5 8.2 3.2 5.5 5.6 1.9 5.1 2.7 5.0 4.2 2.1 2.8 3.5 5.0 4.8 2.7 8.5 5.2 3.7 6.7 5.3 3.0 4.1 3.4 5.7 0.9 1.9 5.5 3.0 2.4 3.6 4.2 2.7 1.6 4.0 3.7 0.2 1.7 2.0 4.5 2.0 3.3 0.5 1.8 0.7 5.0 0.2 2.7 5.9 1.7 0.1 2.8 1.0 7.5 3.9 1.3 3.7 1.1 4.7 3.1 1.4 2.9 3.5 3.4 1.2 1.9 9.0 6.3 0.6 5.1 10.2 1.3 8.3 2.2 0.5 7.1 2.6 6.8 0.9 2.7 4.8 3.2 3.3 1.2 2.6 6.2 2.7 1.6 7.5 8.3 6.5 1.5 3.4 2.9 0.5 0.6 3.4 1.5 0.5 2.7 0.6 1.2 2.3 0.5 2.5 2.4 1.7 2.1 2.0 1.7 0.5 1.4 0.7 5.1 5.1 6.0 6.1 4.9 5.6 5.2 5.6 5.5 5.0 5.2 5.7 1.7 9.6 4.5 11.4 4.9 0.8 3.2 2.1 4.0 6.1 2.4 2.4 9.9 4.3 4.4 0.0 4.2 1.5 1.6 0.6 3.9 2.8 4.7 2.3 3.8 2.3 1.2 2.5 14.6 1.4 1.1 2.6 4.6 1.7 1.3 5.9 0.4 0.6 0.9 5.0 12.7 1.0 4.1 0.6 0.8 2.0 2.8 1.1 5.4 2.8 0.9 3.4 4.1 20.6 12.1 1.1 0.1 4.5 2.0 2.3 1.0 0.9 2.9 2.2 6.6 3.1 3.6 11.6 10.5 2.1 0.6 1.4 2.9 3.8 0.6 1.5 TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 55.3;testis: 144.0" "Group enriched" "Detected in some" 23 "Early spermatids: 1336.2;Late spermatids: 1946.7" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 18 "U-266/70: 96.7;U-266/84: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" NA NA 32000000 "Cluster 35: T-regs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" 14.9 0.4 0.4 6.9 0.3 16.1 0.4 0.3 1.4 0.1 1.8 1.1 0.4 0.0 1.3 0.1 0.1 1.3 0.7 0.5 0.4 3.4 16.3 1.6 55.3 0.5 0.4 0.0 0.2 0.1 0.0 5.0 0.5 0.3 0.8 0.0 0.2 0.0 0.1 0.3 1.7 1.0 0.3 8.0 0.2 144.0 0.5 22.4 1.1 0.0 17.4 4.8 0.1 0.5 0.1 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 96.7 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.3 2.4 0.0 0.0 1.6 1.6 0.0 0.0 0.0 0.0 4.0 0.7 0.4 0.3 0.3 1.4 0.5 0.4 0.5 0.4 0.5 0.3 0.5 0.5 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.4 5.9 0.1 1336.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.7 0.3 46.4 0.0 0.3 0.0 0.0 69.4 1.9 1946.7 14.9 1.9 0.0 2.8 0.0 0.0 1.0 0.0 0.3 0.0 0.0 10.9 6.5 0.0 0.0 0.8 0.0 0.0 13.1 0.0 0.1 16.6 8.1 0.0 0.0 0.3 1.7 0.1 0.1 0.0 TJP1 "DKFZp686M05161, MGC133289, ZO-1" ENSG00000104067 "Tight junction protein 1" Q07157 15 29699367-29968915 "Predicted intracellular proteins, Transporters" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 893.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001636, HPA001637, CAB010822" Enhanced Enhanced "Cell Junctions" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Cell Junctions" "CAB010822: , HPA001636: AB_1080762, HPA001637: AB_1080760" "unprognostic (2.11e-2)" "unprognostic (6.83e-2)" "unprognostic (1.21e-1)" "unprognostic (2.81e-2)" "unprognostic (9.43e-2)" "unprognostic (1.21e-1)" "unprognostic (4.54e-2)" "unprognostic (6.71e-3)" "unprognostic (1.98e-1)" "unprognostic (2.86e-1)" "unprognostic (2.86e-3)" "unprognostic (3.54e-1)" "prognostic favorable (1.72e-4)" "unprognostic (2.85e-3)" "unprognostic (3.02e-1)" "unprognostic (5.04e-2)" "unprognostic (1.20e-1)" 37.4 16.5 22.1 4.4 35.3 1.1 30.8 21.4 24.4 33.2 17.9 30.5 7.1 42.3 16.5 60.4 27.8 12.6 37.1 22.0 22.2 24.3 18.6 34.0 5.7 26.6 28.6 22.3 30.0 13.4 16.8 31.6 25.2 20.4 9.5 10.0 29.6 10.9 22.0 27.8 19.8 17.4 20.6 13.5 25.8 29.7 30.3 3.7 24.8 5.0 10.2 23.8 35.3 42.6 62.4 36.8 29.1 18.4 17.0 31.7 28.9 18.6 21.1 18.0 20.2 59.2 22.9 0.3 24.8 24.6 21.3 47.4 20.1 23.8 19.0 0.5 14.9 0.3 22.3 24.7 57.9 0.1 0.8 16.5 15.8 21.4 39.2 23.0 38.2 0.1 24.3 12.5 14.2 32.2 0.2 0.7 21.9 23.4 14.6 0.1 35.0 0.2 28.1 33.4 12.9 16.8 39.2 12.8 16.8 42.9 13.3 0.6 54.7 14.3 23.9 12.5 25.6 4.4 4.6 0.4 17.8 0.3 9.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.1 35.3 21.4 24.4 22.0 22.2 26.6 28.6 25.2 20.6 30.3 42.6 212.1 169.9 49.2 299.7 1.6 35.8 115.2 36.4 39.3 42.4 53.7 28.6 107.2 51.5 48.6 58.8 10.4 32.3 0.8 87.7 25.4 116.0 19.1 132.2 97.0 166.0 46.0 2.7 293.8 83.7 11.3 56.6 86.6 290.7 5.7 87.7 100.3 49.1 3.8 126.2 187.3 45.4 32.6 6.1 12.1 13.7 33.8 5.2 64.0 266.1 1.6 32.8 0.0 345.3 893.8 178.3 82.0 63.9 5.9 151.4 37.8 26.0 39.2 52.4 78.9 64.1 118.7 63.0 83.9 139.2 60.1 33.7 4.1 120.8 33.1 194.6 TJP2 "DFNA51, X104, ZO-2, ZO2" ENSG00000119139 "Tight junction protein 2" Q9UDY2 9 69121264-69274615 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 212.4;Rod photoreceptor cells: 267.6;Urothelial cells: 244.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "A-431: 237.5" "Low region specificity" "Detected in all" "HPA001813, CAB009228, HPA070714" Supported Enhanced "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA 580000 "Cluster 35: T-regs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cell Junctions" Nucleoplasm "CAB009228: AB_2203583, HPA001813: AB_1080764, HPA070714: AB_2732161" "unprognostic (1.30e-1)" "unprognostic (7.69e-2)" "unprognostic (1.23e-3)" "unprognostic (7.68e-2)" "unprognostic (2.01e-1)" "unprognostic (8.83e-3)" "unprognostic (1.94e-2)" "unprognostic (1.86e-1)" "unprognostic (4.82e-2)" "unprognostic (3.30e-2)" "unprognostic (2.93e-3)" "unprognostic (3.60e-1)" "prognostic favorable (1.78e-14)" "unprognostic (3.29e-2)" "unprognostic (6.42e-2)" "unprognostic (8.15e-3)" "unprognostic (5.85e-2)" 44.4 14.9 35.1 11.6 45.3 12.0 30.2 44.5 42.6 16.9 25.7 39.0 54.4 19.8 13.1 45.8 23.8 24.4 35.8 38.0 45.4 44.7 64.8 47.6 9.7 52.6 39.9 37.0 21.9 57.9 5.3 18.4 52.6 24.8 35.1 122.0 37.1 21.9 14.1 35.0 49.6 16.1 55.0 5.7 58.3 32.1 39.9 32.5 44.9 15.1 23.1 55.3 22.3 66.3 237.5 6.4 24.4 25.8 92.9 90.3 108.5 37.3 26.7 54.9 29.0 31.8 106.6 33.0 37.0 20.3 31.4 158.3 33.2 79.3 75.9 115.3 20.7 34.5 22.5 165.2 28.9 13.8 59.1 71.3 65.2 43.1 32.4 19.6 143.6 9.9 19.7 24.7 34.3 36.0 5.5 2.3 49.5 194.5 50.0 23.1 26.9 2.9 192.0 194.2 8.3 14.9 13.3 111.2 3.4 55.7 37.0 7.9 196.3 44.3 48.3 32.4 38.6 23.0 5.2 0.9 48.0 19.6 16.1 0.0 0.3 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 2.2 0.1 0.8 0.1 35.1 45.3 44.5 42.6 38.0 45.4 52.6 39.9 52.6 55.0 39.9 66.3 2.9 44.8 22.8 76.4 2.3 65.1 79.1 26.3 4.6 212.4 4.6 1.3 38.5 40.0 33.1 3.7 35.5 27.9 2.7 74.4 0.0 32.5 3.5 7.1 1.7 36.4 11.5 10.5 10.1 24.3 25.6 15.5 64.2 9.9 5.7 0.2 27.5 104.9 5.6 18.5 13.4 45.0 36.7 14.6 28.9 6.7 29.2 8.2 28.4 22.5 9.0 111.1 1.0 21.6 82.5 44.2 65.8 13.9 5.2 115.4 73.4 1.9 51.3 267.6 0.0 4.9 13.1 19.6 18.0 40.6 64.1 43.2 3.2 0.2 50.3 244.5 TJP3 ZO-3 ENSG00000105289 "Tight junction protein 3" O95049 19 3708362-3750813 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 43.0;stomach 1: 27.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 238.7;Early spermatids: 405.1;Paneth cells: 140.4;Proximal enterocytes: 130.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 1.2;MAIT T-cell: 3.9;memory CD4 T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD4 T-cell: 3.3;naive CD8 T-cell: 1.2;T-reg: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.9" "Cell line enhanced" "Detected in some" "BEWO: 44.0;CAPAN-2: 41.1;MCF7: 20.3;OE19: 37.4;SK-BR-3: 25.7;T-47d: 52.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "CAB013244, HPA046863, HPA053337" Enhanced Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cell Junctions" "CAB013244: AB_2533257, HPA046863: AB_2679845, HPA053337: AB_2682118" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.83e-6)" "unprognostic (2.78e-1)" "prognostic favorable (9.52e-4)" "unprognostic (1.30e-1)" "unprognostic (1.25e-1)" "unprognostic (2.52e-1)" "unprognostic (6.52e-2)" "unprognostic (2.15e-2)" "unprognostic (1.78e-1)" "prognostic favorable (9.36e-8)" "unprognostic (8.58e-3)" "unprognostic (5.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.62e-3)" 0.2 0.0 0.2 4.7 0.1 0.1 4.0 0.1 0.4 6.3 7.4 34.1 43.0 1.5 2.4 25.5 13.7 6.2 0.0 0.4 0.1 5.8 7.1 5.2 0.4 0.2 0.4 0.1 6.4 7.5 1.7 1.6 0.2 4.0 13.2 0.1 20.8 5.3 0.7 7.3 37.4 0.5 0.0 0.5 27.0 2.5 0.0 0.2 6.9 0.0 2.6 4.1 6.0 0.3 0.3 8.3 0.0 0.0 0.0 0.0 44.0 0.0 0.0 0.0 0.0 13.0 41.1 8.2 1.3 0.0 0.1 10.4 0.6 0.0 0.0 0.5 0.2 0.0 0.7 2.9 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.1 0.3 0.0 20.3 0.0 0.3 0.9 37.4 0.2 0.1 0.0 6.2 1.4 6.8 0.2 0.2 1.6 25.7 0.0 3.3 52.2 0.2 0.0 0.1 1.0 0.1 0.0 1.7 2.5 0.1 0.0 0.5 0.0 0.0 0.0 0.0 1.2 0.0 3.9 0.4 3.1 2.4 0.0 0.6 3.3 1.2 0.0 0.0 0.0 0.0 3.8 1.2 0.2 0.1 0.1 0.4 0.4 0.1 0.2 0.4 0.2 0.0 0.0 0.3 0.1 9.6 13.7 0.3 1.9 0.0 7.0 21.0 0.0 0.0 20.3 6.3 0.9 34.3 42.1 31.3 0.0 32.1 0.8 238.7 19.6 21.1 405.1 31.2 1.1 0.5 12.5 0.0 0.9 23.6 4.2 0.6 52.5 13.2 4.5 0.1 0.0 7.3 2.7 0.0 0.9 50.9 24.4 0.3 0.3 36.5 1.8 0.8 3.6 0.0 0.1 0.0 0.0 0.5 1.4 21.8 140.4 1.2 0.2 6.5 130.4 8.0 86.1 0.0 0.0 0.0 3.4 4.3 4.8 8.0 0.1 40.2 4.3 0.0 62.1 25.6 TLN1 "ILWEQ, TLN" ENSG00000137076 "Talin 1" Q9Y490 9 35696948-35732195 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Macrophages: 323.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002006, HPA004748" Supported Supported "Plasma membrane,Focal adhesion sites,Centriolar satellite,Cytosol" NA NA 1300000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites, Cytosol" "Plasma membrane, Centriolar satellite" "CAB002006: , HPA004748: AB_1857760" "unprognostic (9.71e-2)" "unprognostic (2.02e-2)" "prognostic unfavorable (5.56e-4)" "unprognostic (1.96e-1)" "unprognostic (5.55e-2)" "unprognostic (2.52e-1)" "unprognostic (3.18e-2)" "unprognostic (5.07e-2)" "unprognostic (1.94e-1)" "unprognostic (6.46e-2)" "unprognostic (1.82e-1)" "unprognostic (1.27e-1)" "prognostic favorable (7.21e-4)" "unprognostic (1.36e-1)" "unprognostic (2.71e-2)" "unprognostic (7.83e-2)" "unprognostic (8.83e-3)" 125.7 62.7 31.1 84.7 42.1 79.2 79.4 39.3 31.1 80.0 43.1 196.2 36.5 151.8 25.3 78.0 102.9 53.2 81.2 26.2 34.9 47.3 42.3 91.8 63.1 50.8 41.9 66.0 33.1 41.6 36.7 70.4 49.7 72.6 41.4 7.7 42.5 111.4 70.9 46.7 77.9 145.4 41.5 89.7 91.8 23.3 44.9 61.1 49.0 55.8 52.7 147.7 66.3 44.6 63.4 103.8 62.7 86.9 210.8 158.7 71.4 171.2 186.8 162.9 146.4 86.3 27.4 76.5 55.5 319.0 103.0 33.3 74.2 106.9 118.3 172.8 48.0 173.0 132.1 77.4 130.6 105.8 276.2 193.4 50.2 240.1 112.7 223.7 253.4 64.7 60.2 76.0 218.5 27.8 71.5 27.8 51.3 28.4 78.8 95.0 36.6 44.8 81.4 49.8 14.1 59.6 83.7 46.3 53.4 56.5 39.3 72.6 308.5 257.8 99.6 80.0 140.6 26.2 27.6 51.7 199.9 55.9 238.4 6.0 5.9 7.3 5.4 6.1 4.4 2.6 3.1 4.1 4.3 2.3 1.4 3.1 10.0 4.1 8.1 5.4 2.3 6.9 31.1 42.1 39.3 31.1 26.2 34.9 50.8 41.9 49.7 41.5 44.9 44.6 123.2 109.0 66.9 11.4 99.8 40.1 69.4 43.5 42.7 11.7 40.3 61.3 134.1 31.5 55.7 53.3 10.4 44.3 186.3 43.8 23.5 94.3 47.2 36.0 156.9 106.8 34.1 127.0 7.7 61.9 82.6 103.9 51.0 73.0 206.6 72.0 93.9 54.7 112.4 15.2 7.6 29.0 26.4 196.9 91.0 26.4 99.4 323.4 23.2 21.5 174.1 33.0 288.4 4.5 9.1 107.7 33.2 128.6 61.4 58.4 40.6 62.8 34.3 17.6 203.8 126.5 267.9 32.0 28.5 47.4 26.6 58.8 143.8 89.4 28.9 46.4 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TM2D2 BLP1 ENSG00000169490 "TM2 domain containing 2" Q9BX73 8 38988808-38996824 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 218.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047152, HPA050547" Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Vesicles, Plasma membrane" "HPA047152: AB_2679957, HPA050547: AB_2681168" "prognostic unfavorable (7.49e-4)" "unprognostic (1.49e-1)" "prognostic favorable (1.71e-4)" "unprognostic (2.55e-2)" "unprognostic (7.02e-2)" "unprognostic (2.98e-1)" "unprognostic (5.17e-2)" "unprognostic (1.41e-1)" "unprognostic (3.69e-2)" "unprognostic (2.43e-3)" "unprognostic (4.58e-2)" "unprognostic (1.18e-2)" "unprognostic (1.14e-1)" "unprognostic (1.41e-1)" "unprognostic (1.61e-1)" "unprognostic (1.07e-2)" "unprognostic (8.61e-2)" 20.2 24.4 15.6 15.9 17.3 13.1 19.8 18.2 22.2 19.7 24.4 15.7 18.0 18.4 26.5 16.5 17.4 23.1 19.5 17.5 18.6 32.9 29.8 20.6 17.7 16.5 17.4 22.0 13.9 23.6 15.9 33.8 17.6 22.2 16.3 17.1 17.8 22.1 15.6 18.5 16.2 17.8 17.2 22.3 19.6 27.6 18.0 11.8 26.4 17.6 15.2 20.0 16.6 19.7 35.7 56.5 25.7 35.7 58.8 39.0 35.4 73.8 44.9 54.6 49.1 43.4 30.0 12.5 56.7 54.9 61.5 37.8 27.5 44.5 59.0 15.0 21.7 28.6 32.3 47.3 51.8 8.6 35.3 47.9 42.8 43.1 20.9 40.0 71.1 21.2 32.2 35.7 73.5 22.1 21.3 28.9 32.6 53.2 22.0 17.8 33.2 21.0 62.2 27.9 8.6 16.9 28.2 19.5 37.8 45.1 48.1 17.9 64.6 44.0 33.0 64.9 37.7 24.9 59.1 21.9 33.6 19.4 31.6 64.5 28.5 27.3 29.7 34.2 33.3 24.9 35.1 33.0 30.4 26.2 33.1 32.0 7.9 33.0 29.8 60.5 41.8 35.3 15.6 17.3 18.2 22.2 17.5 18.6 16.5 17.4 17.6 17.2 18.0 19.7 30.4 12.8 14.7 3.9 13.8 35.1 56.9 64.3 20.5 25.1 22.5 25.1 17.7 32.9 44.5 51.5 20.9 91.3 28.2 12.9 29.4 59.9 62.2 24.1 33.3 36.0 10.3 5.9 7.6 38.4 98.2 38.6 17.3 25.8 22.2 44.3 58.2 38.4 218.5 23.5 9.2 12.6 40.7 33.6 33.9 46.6 36.1 40.6 26.6 7.5 70.8 45.4 15.5 6.0 5.4 74.9 19.4 24.8 14.5 52.5 35.1 61.4 29.4 34.0 0.0 25.4 26.5 60.8 58.1 16.3 15.5 79.9 17.8 39.3 16.7 48.5 TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 266.6" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 703.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.6;RPMI-8226: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" 0.1 0.1 0.2 0.3 0.2 0.2 0.0 1.2 0.4 0.0 0.4 3.1 266.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.3 0.0 0.0 0.0 0.3 144.5 1.6 0.0 0.1 0.5 3.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 1.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 48.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.4 0.0 0.0 0.0 77.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 157.9 0.7 0.0 0.0 703.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 18.8 0.0 TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 945.8;intestine: 650.8;liver: 703.8" "Group enriched" "Detected in some" 17 "Cholangiocytes: 2070.3;Hepatocytes: 578.1" "Group enriched" "Detected in many" 10 "liver cancer: 249.4;pancreatic cancer: 130.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 22.7;OE19: 20.3;RPTEC TERT1: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Cytosol "HPA046430: AB_2679662" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.83e-1)" "unprognostic (4.66e-2)" "unprognostic (1.91e-2)" "unprognostic (4.97e-1)" 0.3 1.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.0 650.8 0.6 2.3 0.7 0.5 945.8 0.3 0.0 0.0 0.8 703.8 0.3 0.8 0.0 0.0 0.0 72.5 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 514.8 0.9 0.0 0.1 21.3 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.6 0.3 0.2 4.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.8 0.1 20.3 0.0 0.0 0.5 1.4 36.5 0.0 0.6 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.1 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 4.1 2070.3 0.6 0.0 0.0 0.0 0.0 0.8 0.0 25.9 1.1 3.1 0.3 0.6 3.0 13.5 0.1 2.0 0.2 0.1 10.7 3.3 0.0 0.0 7.1 578.1 0.1 0.0 0.1 41.6 0.0 11.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 8.2 17.5 0.0 0.3 0.0 76.6 4.8 0.1 0.0 0.0 0.0 0.7 4.1 0.3 0.0 0.0 0.1 0.5 5.6 2.0 0.2 TM4SF5 ENSG00000142484 "Transmembrane 4 L six family member 5" O14894 17 4771884-4783213 "Predicted membrane proteins, Transporters" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "intestine: 174.7;liver: 204.6" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 115.2;Hepatocytes: 275.4;Intestinal goblet cells: 143.9;Paneth cells: 285.4;Proximal enterocytes: 618.4" "Cancer enriched" "Detected in many" 9 "liver cancer: 219.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "CACO-2: 53.7;Hep G2: 96.0;OE19: 60.0" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA055674 Uncertain "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cell Junctions" Nucleoplasm "HPA055674: " "unprognostic (1.81e-1)" "unprognostic (1.61e-1)" "unprognostic (1.31e-1)" "unprognostic (4.44e-2)" "unprognostic (9.33e-2)" "unprognostic (3.57e-2)" "unprognostic (1.95e-1)" "unprognostic (5.21e-3)" 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.4 174.7 0.1 0.0 0.0 0.0 3.2 0.0 0.0 0.0 11.6 204.6 0.0 0.2 0.0 0.0 0.0 1.4 8.1 0.0 0.6 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 158.1 0.0 0.0 0.1 28.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 53.7 2.6 0.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.2 96.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.7 0.0 60.0 0.2 0.0 0.0 1.2 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.8 0.0 1.8 0.0 0.1 0.0 40.5 5.9 0.9 2.0 0.0 0.0 0.1 115.2 5.3 0.1 8.9 4.6 0.0 57.6 0.0 4.5 0.0 4.6 275.4 0.1 0.0 0.1 143.9 0.0 4.8 0.3 2.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.0 285.4 0.0 0.1 0.0 618.4 72.8 0.1 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.5 0.0 47.8 0.0 TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.4;stomach 1: 46.0" "Cell type enhanced" "Detected in many" "Club cells: 282.4;Pancreatic endocrine cells: 302.2;Proximal enterocytes: 374.3;Respiratory ciliated cells: 624.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 69.7;OE19: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" 0.6 0.1 0.2 3.1 0.4 1.5 12.7 0.5 0.3 8.9 5.6 21.6 45.4 2.1 17.5 1.2 5.1 25.5 0.1 0.3 0.0 0.3 0.6 18.9 0.2 0.2 0.2 0.1 2.3 6.0 0.1 3.2 0.2 12.2 22.7 0.2 22.8 0.2 0.1 1.8 53.4 1.1 0.0 0.1 46.0 3.8 0.2 0.1 0.7 0.0 1.1 3.2 0.5 0.2 6.9 10.8 0.0 0.3 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.1 69.7 0.0 0.3 0.0 0.2 4.4 1.1 0.0 0.0 0.1 0.1 0.0 1.8 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.1 0.0 0.2 2.5 41.5 3.1 0.0 0.0 2.6 0.1 0.3 0.7 0.2 0.1 2.1 0.0 1.1 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.1 157.0 162.5 0.0 1.8 0.8 22.9 46.6 2.8 0.3 57.4 17.9 0.9 102.9 282.4 22.0 2.1 39.0 1.0 173.7 0.0 121.1 32.8 107.0 6.9 2.9 38.9 8.0 1.9 166.3 3.4 3.3 188.1 88.4 5.7 11.0 0.7 0.6 2.7 3.3 2.0 101.5 26.4 0.0 1.1 32.6 0.3 1.8 1.8 0.0 1.0 0.2 0.0 0.5 0.9 302.2 180.9 0.7 0.5 103.1 374.3 2.0 624.7 1.9 0.0 0.4 9.5 1.3 1.1 2.2 1.7 16.3 1.3 1.5 125.1 55.9 TMCO5A "MGC35118, TMCO5" ENSG00000166069 "Transmembrane and coiled-coil domains 5A" Q8N6Q1 15 37921939-37967724 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 141 "testis: 90.7" "Group enriched" "Detected in some" 104 "Early spermatids: 1153.9;Late spermatids: 3910.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA056530, HPA064017" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA056530: AB_2683167, HPA064017: " "unprognostic (2.60e-1)" "unprognostic (1.69e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 90.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1153.9 0.2 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3910.6 13.4 1.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.1 0.0 6.6 0.0 0.0 24.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TMED8 FAM15B ENSG00000100580 "Transmembrane p24 trafficking protein family member 8" Q6PL24 14 77335029-77377094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.7;Cone photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001205 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "HPA001205: AB_2204460" "unprognostic (1.07e-1)" "unprognostic (4.70e-2)" "unprognostic (4.85e-2)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (7.82e-2)" "unprognostic (1.68e-2)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (2.77e-1)" 5.5 8.3 8.2 8.6 9.6 7.7 5.7 4.7 8.4 5.9 4.1 4.4 3.3 6.7 5.1 3.6 5.4 4.1 3.4 7.5 16.6 10.4 3.4 4.6 17.5 7.9 10.5 7.3 5.6 11.1 9.2 4.4 11.2 5.9 4.8 24.2 4.4 5.9 2.3 4.9 5.5 5.6 6.9 8.0 6.2 6.8 12.8 9.8 10.9 2.4 19.5 4.7 3.5 5.9 14.7 12.0 13.9 12.4 8.5 7.6 11.8 9.2 6.0 9.4 10.1 7.5 8.1 58.7 7.5 7.5 7.7 10.0 10.4 10.5 14.6 18.6 6.3 19.6 9.5 7.9 5.9 9.6 51.8 8.0 7.4 12.3 11.0 9.5 13.5 47.7 10.1 15.4 9.5 14.4 15.2 14.2 6.9 10.7 12.0 12.2 12.7 4.7 9.9 9.0 17.2 10.4 15.9 9.4 11.8 10.6 15.2 15.9 9.7 9.7 6.2 17.5 10.7 12.3 25.2 28.9 11.1 17.7 14.3 2.3 0.7 2.2 0.3 0.9 0.4 2.1 0.5 0.4 0.6 2.1 0.3 0.5 1.0 0.5 0.8 1.0 0.7 0.5 8.2 9.6 4.7 8.4 7.5 16.6 7.9 10.5 11.2 6.9 12.8 5.9 6.6 3.2 7.8 62.7 33.9 6.6 4.9 7.7 2.8 33.4 12.5 8.3 16.8 8.6 5.3 22.0 108.4 10.5 7.9 6.5 5.9 6.4 4.8 9.8 15.5 10.4 44.3 15.4 44.7 4.7 10.0 8.4 7.1 9.0 0.0 9.1 8.9 9.8 7.8 28.6 40.7 6.3 10.2 24.8 7.7 6.9 14.6 19.8 5.4 21.5 16.8 14.9 6.2 39.7 24.2 6.8 3.3 14.3 19.9 7.5 3.2 22.2 20.9 39.3 13.1 7.1 8.4 6.8 15.7 8.2 8.9 4.1 10.3 19.8 6.7 4.3 TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 237.2;Glandular and luminal cells: 507.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" 17.2 19.8 22.6 12.9 26.8 11.5 107.0 23.2 24.0 44.4 24.2 20.6 16.9 63.5 27.6 28.0 37.9 15.9 23.1 22.2 22.7 93.9 24.1 18.7 19.4 24.2 24.0 22.7 39.2 26.4 15.4 21.6 23.2 24.0 16.9 12.1 30.1 111.8 33.3 29.0 17.4 16.1 23.5 20.4 28.8 23.6 23.9 16.5 23.0 24.9 17.7 20.4 23.0 23.4 23.5 56.0 19.7 16.2 45.7 43.9 19.6 24.1 36.1 46.5 43.8 42.0 59.5 26.1 6.5 24.9 36.0 35.3 22.9 41.5 35.2 28.5 46.1 19.5 45.7 86.2 39.3 31.7 32.8 39.4 46.5 32.8 46.3 41.8 40.8 45.0 40.7 50.1 29.2 31.7 34.6 36.6 9.1 25.4 62.6 29.8 42.8 47.4 39.1 18.7 25.3 20.2 14.6 0.5 59.6 24.9 27.3 59.9 24.7 42.1 28.5 18.8 46.9 52.1 38.0 12.0 44.3 29.7 38.2 20.1 42.8 15.3 31.2 43.4 35.7 37.3 39.6 36.4 44.9 39.8 43.2 35.7 15.9 44.1 32.9 44.0 44.6 31.1 22.6 26.8 23.2 24.0 22.2 22.7 24.2 24.0 23.2 23.5 23.9 23.4 22.1 19.2 15.4 0.0 22.8 20.6 31.6 72.0 21.6 10.4 64.2 61.2 27.3 24.3 34.5 40.5 6.2 68.5 19.6 18.5 37.2 36.6 13.1 237.2 70.8 28.2 23.4 33.2 0.0 49.8 47.3 21.1 13.7 507.4 22.9 34.4 36.0 20.6 37.6 11.8 0.0 37.3 28.5 32.4 11.8 11.1 13.1 23.8 33.8 0.0 47.7 17.7 29.9 0.0 0.0 41.8 20.7 12.4 29.4 23.4 27.7 30.2 27.1 11.7 6.6 13.2 19.8 45.8 24.7 26.9 22.6 44.6 20.9 25.6 45.7 25.2 TMEM107 "JBTS29, MGC10744, MKS13" ENSG00000179029 "Transmembrane protein 107" Q6UX40 17 8172457-8176399 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cilium biogenesis/degradation" "Developmental protein" "Ciliopathy, Disease variant, Meckel syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Plasma cells: 110.8;Respiratory ciliated cells: 164.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052555, HPA059653" Approved Approved "Nucleoplasm,Plasma membrane,Midbody ring" Yes No "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 55: Plasma cells - Humoral immune response" "Nucleoplasm, Plasma membrane" "Midbody ring" "HPA052555: AB_2681870, HPA059653: AB_2684096" "unprognostic (2.87e-2)" "unprognostic (2.67e-1)" "unprognostic (2.85e-2)" "prognostic favorable (9.39e-5)" "unprognostic (1.94e-2)" "unprognostic (8.83e-2)" "unprognostic (5.70e-3)" "unprognostic (1.24e-1)" "unprognostic (2.15e-1)" "unprognostic (6.02e-3)" "unprognostic (1.83e-2)" "unprognostic (1.87e-1)" "unprognostic (2.66e-3)" "unprognostic (1.26e-1)" "unprognostic (4.99e-1)" "unprognostic (2.66e-1)" "unprognostic (1.49e-1)" 9.6 13.4 11.1 6.6 12.0 15.0 9.8 12.2 13.3 10.6 19.3 9.0 3.5 11.3 20.7 10.5 27.0 7.2 9.2 11.9 12.8 14.7 4.4 11.3 7.4 13.0 12.6 7.8 11.2 16.9 23.5 6.8 12.2 7.3 5.0 29.6 10.7 6.5 1.6 12.0 7.6 6.6 12.1 13.7 8.0 17.1 12.3 8.9 16.1 1.8 7.6 8.4 9.6 12.5 45.0 16.9 21.8 11.3 12.2 17.8 4.8 11.1 8.2 8.2 10.9 2.0 26.6 10.5 14.6 9.7 7.4 30.5 8.3 16.9 13.6 18.1 11.5 7.6 29.0 4.7 4.9 2.6 8.3 7.9 11.2 20.7 9.4 18.4 13.1 17.7 5.9 23.5 18.0 12.2 6.8 7.7 2.2 6.3 7.2 13.1 6.5 19.1 15.8 3.5 7.3 10.7 13.5 2.4 9.1 5.1 8.1 8.8 10.6 4.8 9.6 7.6 6.1 9.5 5.5 4.9 27.3 10.0 8.7 21.0 22.1 51.6 28.2 27.9 24.3 45.4 27.6 30.3 19.7 59.2 30.9 32.2 20.0 26.4 56.8 31.6 24.8 21.0 11.1 12.0 12.2 13.3 11.9 12.8 13.0 12.6 12.2 12.1 12.3 12.5 30.8 9.6 9.8 2.9 38.1 19.2 19.5 35.2 11.4 17.3 31.1 43.3 7.9 35.8 25.1 33.1 45.9 17.3 30.0 12.9 13.7 21.7 12.2 99.9 22.9 25.1 9.1 15.4 5.1 11.1 21.3 18.2 48.9 26.9 36.7 12.7 27.1 24.0 45.5 11.8 3.6 14.1 16.2 45.6 31.6 10.1 12.8 55.9 33.8 3.7 22.0 37.7 28.8 1.5 1.7 11.0 12.7 15.1 110.8 16.3 26.0 21.7 164.3 63.2 0.0 15.3 16.8 69.4 50.3 13.0 28.6 13.3 34.8 13.2 17.6 11.1 TMEM108 "CT124, MGC3040" ENSG00000144868 "Transmembrane protein 108" Q6UXF1 3 133038391-133397775 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 35.2;skeletal muscle: 23.1" "Cell type enhanced" "Detected in many" "Astrocytes: 209.9;Excitatory neurons: 357.3;Inhibitory neurons: 475.3;Oligodendrocyte precursor cells: 480.0" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 24.2;LHCN-M2: 13.8;SCLC-21H: 21.0;SH-SY5Y: 92.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063350 Enhanced Approved "Nucleoli,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 55000 "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "Nucleoli, Vesicles" "HPA063350: AB_2684993" "unprognostic (4.75e-2)" "unprognostic (1.73e-2)" "unprognostic (9.00e-2)" "unprognostic (1.92e-2)" "unprognostic (3.07e-3)" "unprognostic (3.17e-1)" "unprognostic (1.28e-1)" "unprognostic (3.65e-2)" "unprognostic (2.06e-4)" "unprognostic (2.08e-1)" "unprognostic (7.27e-4)" "unprognostic (1.11e-1)" "unprognostic (3.03e-4)" "unprognostic (1.60e-3)" "unprognostic (1.61e-2)" "unprognostic (6.12e-2)" "unprognostic (1.36e-2)" 1.4 11.3 6.3 1.5 9.6 0.2 1.5 3.4 10.0 2.0 3.2 1.5 0.4 2.4 0.6 9.6 1.7 0.8 6.8 9.6 2.9 0.4 0.1 11.0 1.7 0.0 4.1 0.3 0.3 3.0 2.2 2.4 4.0 1.0 1.3 35.2 1.3 2.0 23.1 1.4 1.6 5.5 0.0 1.3 1.3 13.9 7.9 1.3 3.1 7.0 2.3 8.3 0.8 0.8 0.0 0.0 4.1 0.0 0.0 0.1 0.0 0.2 0.0 1.1 0.0 0.3 0.0 0.1 1.0 0.0 0.0 0.1 0.2 0.0 0.7 1.0 1.8 8.5 0.0 0.0 0.0 0.0 24.2 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.1 13.8 0.7 0.1 0.3 3.8 0.0 0.0 0.0 4.8 0.1 1.1 0.0 21.0 92.6 0.0 0.1 0.3 5.5 0.2 0.0 0.0 0.1 0.1 0.0 3.4 1.3 0.0 0.7 1.8 0.0 3.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 9.6 3.4 10.0 9.6 2.9 0.0 4.1 4.0 0.0 7.9 0.8 0.6 3.2 4.6 209.9 0.0 2.4 0.5 0.2 0.0 10.4 1.3 2.8 1.7 1.5 5.0 0.0 102.2 1.8 0.0 0.0 0.0 0.0 80.6 1.0 0.6 1.3 0.0 0.0 357.3 0.4 8.6 4.6 4.1 0.2 1.3 5.5 0.4 0.0 0.3 1.7 475.3 0.0 0.0 0.0 0.8 38.2 0.9 0.1 0.0 33.7 0.0 5.7 0.0 480.0 22.2 0.3 0.0 0.7 1.2 0.2 0.0 0.0 0.0 57.6 0.0 6.8 3.3 17.2 11.2 0.0 1.6 1.1 1.0 4.9 0.0 0.4 TMEM121B CECR6 ENSG00000183307 "Transmembrane protein 121B" Q9BXQ6 22 17116297-17121367 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.7;prostate: 6.6" "Cell type enhanced" "Detected in some" "granulocytes: 1.3;Hofbauer cells: 2.8" "Cancer enhanced" "Detected in some" "prostate cancer: 6.0" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 1.1;neutrophil: 1.6" "Group enriched" "Detected in many" 7 "granulocytes: 1.6;monocytes: 1.1" "Cell line enhanced" "Detected in some" "AF22: 6.0;SCLC-21H: 14.2;THP-1: 11.9;U-937: 9.8" "Low region specificity" "Detected in all" HPA068790 Approved Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 43: THP-1 - Innate immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Nucleoplasm, Plasma membrane" "HPA068790: AB_2686036" "unprognostic (2.30e-1)" "unprognostic (1.05e-1)" "unprognostic (7.11e-3)" "unprognostic (4.49e-3)" "unprognostic (3.36e-1)" "unprognostic (7.14e-3)" "unprognostic (1.12e-3)" "unprognostic (5.32e-2)" "unprognostic (1.97e-1)" "unprognostic (2.01e-2)" "unprognostic (6.88e-4)" "unprognostic (6.08e-2)" "unprognostic (3.10e-4)" "unprognostic (1.02e-2)" "unprognostic (4.37e-2)" "unprognostic (3.49e-3)" "unprognostic (1.71e-1)" 0.3 0.6 6.4 0.9 7.5 1.0 0.7 3.5 7.6 0.2 1.5 0.2 0.2 0.3 0.9 0.3 0.3 0.2 1.2 8.7 3.9 0.3 0.1 0.3 0.1 3.8 3.3 0.2 1.1 0.1 1.6 0.7 3.3 6.6 0.2 1.3 0.4 0.2 1.3 0.5 0.2 0.3 3.6 0.7 0.2 1.9 4.9 0.1 0.1 0.4 0.1 0.3 0.2 5.1 0.0 0.0 6.0 0.8 0.0 0.0 0.0 0.1 0.1 0.2 0.4 0.2 0.0 0.2 0.1 0.0 0.2 0.0 0.7 0.0 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 0.0 0.0 0.0 0.0 2.1 0.1 0.1 0.3 0.0 0.8 3.2 2.1 0.0 0.1 0.2 3.0 0.0 0.3 0.1 14.2 2.1 0.0 0.0 0.3 0.8 0.0 11.9 0.6 0.6 0.2 0.2 0.0 0.2 0.4 0.9 0.0 9.8 0.3 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.2 6.4 7.5 3.5 7.6 8.7 3.9 3.8 3.3 3.3 3.6 4.9 5.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 1.3 0.9 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM141 MGC14141 ENSG00000244187 "Transmembrane protein 141" Q96I45 9 136791344-136793317 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 580.8;Distal tubular cells: 626.1;Intestinal goblet cells: 547.5;Paneth cells: 682.0;Proximal enterocytes: 633.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "OE19: 228.2;T-47d: 221.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014615, HPA050244" Approved Supported "Cell Junctions,Mitochondria" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Cell Junctions" "HPA014615: AB_2204756, HPA050244: AB_2681061" "unprognostic (2.05e-1)" "unprognostic (1.88e-2)" "unprognostic (1.07e-1)" "unprognostic (1.14e-1)" "unprognostic (2.00e-1)" "unprognostic (8.53e-3)" "unprognostic (1.52e-2)" "unprognostic (3.15e-2)" "unprognostic (2.38e-1)" "unprognostic (1.94e-2)" "unprognostic (2.24e-1)" "unprognostic (8.45e-2)" "prognostic favorable (6.63e-4)" "unprognostic (1.49e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-1)" "unprognostic (1.70e-1)" 32.7 44.1 37.9 23.3 40.1 40.2 48.7 43.8 42.6 36.4 39.7 120.5 48.4 25.2 63.6 109.6 48.2 27.9 74.0 36.8 41.3 116.8 134.7 39.3 21.1 42.1 40.2 33.4 74.0 83.0 62.2 41.9 44.4 132.3 112.2 12.2 61.5 28.5 38.1 68.7 60.6 22.4 40.0 38.7 76.2 33.1 41.1 29.8 66.3 35.8 26.4 39.2 49.5 44.1 55.0 35.9 34.9 21.1 42.2 34.1 69.9 30.8 47.4 35.9 29.0 47.9 47.5 53.4 44.1 32.5 32.0 78.2 14.0 87.8 11.6 38.7 27.5 30.4 18.0 52.3 60.8 31.1 35.5 33.1 146.4 26.7 79.0 42.3 54.6 67.4 28.9 26.7 48.2 102.0 42.0 21.2 16.7 228.2 43.8 34.6 37.6 156.1 82.1 28.4 55.3 25.7 32.9 125.7 35.1 27.1 221.4 28.9 38.5 24.6 19.9 46.3 19.5 17.0 29.7 28.2 39.9 44.2 37.2 19.5 29.5 20.4 23.1 44.2 20.6 18.2 15.1 16.0 24.1 23.0 20.6 19.5 7.3 29.9 37.4 90.6 16.4 29.1 37.9 40.1 43.8 42.6 36.8 41.3 42.1 40.2 44.4 40.0 41.1 44.1 62.0 57.7 79.0 6.5 39.6 40.7 99.3 120.5 55.2 13.8 128.7 152.9 42.3 124.4 100.9 117.7 8.4 182.4 64.0 580.8 626.1 179.2 48.4 80.1 50.4 48.5 206.9 53.6 8.2 78.5 141.7 59.1 76.5 148.2 41.8 67.5 56.0 171.7 148.5 5.0 6.4 547.5 109.9 61.6 29.8 134.9 37.6 53.7 85.4 2.8 85.7 61.1 78.2 2.5 11.7 90.1 682.0 29.7 34.8 193.7 633.0 459.2 60.9 30.0 46.0 32.4 46.9 57.2 53.5 156.7 62.8 274.3 42.7 65.1 460.1 125.9 TMEM164 "FLJ22679, RP13-360B22.2" ENSG00000157600 "Transmembrane protein 164" Q5U3C3 X 110002631-110182734 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 84.5;Distal enterocytes: 53.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 59.7" "Lineage enriched" "Detected in many" 18 "granulocytes: 59.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038784 Approved Approved "Vesicles,Cell Junctions" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 3: HMC-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" Vesicles "Cell Junctions" "HPA038784: AB_10670790" "unprognostic (2.14e-3)" "unprognostic (3.35e-1)" "unprognostic (1.50e-1)" "unprognostic (3.65e-3)" "unprognostic (7.94e-2)" "unprognostic (3.97e-2)" "prognostic unfavorable (8.17e-6)" "unprognostic (9.85e-3)" "unprognostic (5.68e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-2)" "unprognostic (3.95e-1)" "unprognostic (7.66e-2)" "prognostic favorable (3.14e-4)" "unprognostic (1.76e-1)" "unprognostic (1.81e-2)" "unprognostic (4.19e-3)" 16.9 10.3 11.4 9.6 11.8 19.0 12.3 6.8 9.7 5.5 14.3 18.8 21.5 5.3 6.0 13.8 8.1 5.1 22.7 9.0 12.1 11.1 2.0 17.9 6.7 13.5 13.0 13.8 25.4 8.3 9.6 5.2 11.2 8.9 21.2 3.6 9.8 14.4 27.5 20.3 19.2 6.9 8.2 8.4 14.0 1.9 12.3 12.6 13.8 19.3 8.0 5.8 6.8 8.6 10.8 24.3 19.5 12.8 23.7 17.3 11.9 5.3 12.4 11.0 7.1 19.1 16.6 8.6 35.2 8.3 27.1 15.6 17.1 27.9 10.8 23.9 11.7 58.5 13.0 8.1 13.9 26.1 80.1 24.0 48.4 19.9 27.2 30.2 21.8 15.2 18.4 10.2 19.7 21.6 27.4 33.1 17.5 36.9 17.3 12.4 15.1 7.2 17.5 11.3 18.2 20.3 34.0 33.1 15.9 18.1 9.6 25.7 49.0 9.3 6.8 11.0 7.7 5.9 7.9 6.9 24.3 32.0 25.3 59.7 3.3 14.2 0.6 2.9 1.6 0.2 0.7 0.6 2.7 0.6 0.4 0.5 16.3 2.3 1.8 0.5 1.0 1.8 11.4 11.8 6.8 9.7 9.0 12.1 13.5 13.0 11.2 8.2 12.3 8.6 2.9 3.2 36.1 84.5 3.7 4.8 3.7 4.7 4.6 1.2 11.7 9.1 21.3 11.5 6.9 16.5 2.1 2.7 3.5 53.0 3.9 4.6 0.5 6.7 3.8 6.0 27.6 14.5 22.9 11.4 6.3 3.1 7.7 10.7 3.8 4.3 6.4 1.7 13.6 0.0 31.4 12.7 10.2 25.1 9.4 1.3 1.8 12.5 1.8 24.4 28.1 1.0 4.1 34.2 7.6 13.5 15.0 1.5 1.6 9.0 31.9 3.3 5.4 1.3 0.0 6.4 4.1 0.2 0.3 10.4 8.0 2.7 5.2 3.8 21.2 12.3 TMEM176B "LR8, MS4B2" ENSG00000106565 "Transmembrane protein 176B" Q3YBM2 7 150791285-150801360 "Predicted membrane proteins, Transporters" Differentiation "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "liver: 1656.5" "Cell type enhanced" "Detected in many" "Hepatocytes: 1171.9;monocytes: 502.3;Paneth cells: 762.4;Proximal enterocytes: 922.5;Proximal tubular cells: 976.5" "Cancer enhanced" "Detected in all" "liver cancer: 537.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "classical monocyte: 865.5;intermediate monocyte: 586.0" "Lineage enriched" "Detected in many" 5 "monocytes: 865.5" "Group enriched" "Detected in some" 17 "HSkMC: 642.7;THP-1: 215.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047509 Approved Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA047509: AB_2680072" "unprognostic (5.21e-2)" "unprognostic (7.86e-2)" "unprognostic (1.30e-2)" "unprognostic (8.27e-2)" "unprognostic (3.35e-2)" "unprognostic (6.96e-2)" "unprognostic (7.23e-2)" "unprognostic (2.74e-2)" "unprognostic (5.31e-2)" "unprognostic (1.47e-1)" "unprognostic (5.72e-3)" "unprognostic (7.50e-2)" "unprognostic (3.11e-3)" "unprognostic (5.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.53e-1)" "unprognostic (4.05e-2)" 120.9 49.5 48.5 190.8 50.1 13.5 77.8 50.7 65.8 74.5 43.0 251.8 167.7 25.9 25.7 50.4 81.5 197.3 208.5 45.4 58.0 356.5 1656.5 95.6 177.5 69.2 60.1 143.1 53.6 7.3 22.7 115.0 64.5 48.9 244.9 34.1 42.5 28.3 11.0 34.7 286.6 99.0 65.0 87.0 94.5 11.1 52.2 26.1 33.6 36.1 93.7 158.6 92.4 73.2 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.2 25.7 0.4 0.8 0.0 0.1 0.6 0.1 0.1 0.0 0.1 0.8 0.4 0.0 0.0 0.6 0.8 0.2 642.7 0.0 0.3 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.7 0.1 0.9 0.5 0.1 0.0 0.1 1.0 11.8 0.1 0.0 1.9 1.4 0.6 0.3 0.2 0.2 0.0 215.7 0.0 0.0 3.2 0.5 0.2 0.4 0.2 0.6 0.0 0.3 0.0 5.3 865.5 50.5 2.3 586.0 3.4 2.5 0.6 0.7 164.3 0.6 0.7 0.4 8.6 0.6 309.3 7.7 0.6 498.5 48.5 50.1 50.7 65.8 45.4 58.0 69.2 60.1 64.5 65.0 52.2 73.2 22.2 3.2 9.3 14.4 16.9 12.6 0.5 0.9 5.7 156.9 52.2 74.0 73.7 190.1 14.4 375.2 2.1 0.9 2.8 419.4 166.3 95.1 18.5 6.1 14.5 19.8 128.1 13.5 0.1 34.0 1.0 243.7 14.8 2.1 54.4 61.9 22.9 1171.9 92.5 6.7 0.6 252.1 46.8 98.5 44.4 12.2 43.5 190.0 16.0 8.4 502.3 87.3 1.0 7.5 0.1 65.4 762.4 3.4 1.5 2.5 922.5 976.5 11.3 17.9 0.0 6.7 34.0 4.0 3.8 1.8 15.6 2.7 9.1 0.4 263.7 2.8 TMEM183A C1orf37 ENSG00000163444 "Transmembrane protein 183A" Q8IXX5 1 203007374-203024848 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072607 Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "Nucleoplasm, Cell Junctions" "HPA072607: AB_2686539" "unprognostic (2.94e-3)" "unprognostic (1.60e-1)" "unprognostic (1.30e-1)" "unprognostic (1.33e-1)" "unprognostic (3.41e-2)" "unprognostic (5.99e-2)" "prognostic unfavorable (2.62e-4)" "unprognostic (6.46e-2)" "unprognostic (3.21e-2)" "unprognostic (4.82e-3)" "unprognostic (5.28e-2)" "unprognostic (7.84e-2)" "unprognostic (4.83e-2)" "unprognostic (6.01e-3)" "unprognostic (9.55e-2)" "unprognostic (3.65e-2)" "unprognostic (1.32e-1)" 21.6 19.1 27.6 17.0 28.8 76.6 22.1 28.2 35.1 22.9 23.8 30.9 26.6 19.8 18.8 30.3 19.4 14.1 17.0 30.1 30.1 22.8 23.9 21.0 21.7 26.7 25.8 20.1 28.7 17.8 12.2 14.4 27.7 21.2 30.2 21.8 25.4 16.4 14.8 27.5 26.1 19.9 23.7 22.2 25.2 34.1 26.7 30.0 22.2 12.7 24.1 23.4 22.9 27.0 32.7 31.2 39.2 64.6 50.6 37.7 64.4 32.2 31.7 36.4 31.7 38.1 33.6 81.1 22.6 41.7 14.6 40.4 53.1 45.1 30.1 26.6 64.5 40.2 33.8 42.3 36.6 72.6 33.9 37.3 49.3 30.1 60.2 36.8 46.6 64.4 83.8 28.7 34.5 73.3 59.7 74.4 107.7 44.0 49.2 45.4 66.7 65.7 57.0 31.6 50.2 62.7 48.0 79.0 48.1 61.9 56.6 56.6 34.8 24.4 34.2 42.3 35.7 28.8 49.7 62.4 27.0 55.7 26.3 33.3 33.6 51.2 23.5 29.2 23.1 23.8 26.3 26.6 37.4 26.2 29.8 24.7 28.7 36.6 27.8 26.8 30.6 37.4 27.6 28.8 28.2 35.1 30.1 30.1 26.7 25.8 27.7 23.7 26.7 27.0 39.7 16.0 20.5 3.6 40.4 73.4 61.5 62.2 41.5 22.8 62.2 48.6 14.9 54.3 52.1 35.0 10.4 53.2 57.3 70.4 70.5 88.6 161.1 31.1 34.9 36.2 52.7 103.7 13.2 76.1 86.0 34.8 42.3 34.4 17.7 34.6 40.7 53.6 60.4 18.5 11.8 87.5 63.1 63.1 52.0 113.7 27.1 49.7 39.2 6.5 71.1 26.6 50.4 3.5 7.2 52.7 57.6 29.3 62.1 100.2 102.3 100.4 44.5 28.0 19.7 38.3 46.7 95.0 80.9 72.9 82.1 51.6 48.3 39.6 88.6 105.2 TMEM186 "C16orf51, DKFZP564K2062" ENSG00000184857 "Transmembrane protein 186" Q96B77 16 8780384-8797642 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 44.8;Late spermatids: 106.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018226, HPA063559" Uncertain Approved "Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 31: Spermatids - Spermatogenesis" "Cell Junctions" "HPA018226: AB_1845579, HPA063559: AB_2685041" "unprognostic (3.49e-1)" "unprognostic (1.07e-2)" "unprognostic (1.11e-2)" "unprognostic (2.98e-2)" "unprognostic (4.81e-2)" "unprognostic (1.18e-1)" "unprognostic (2.32e-2)" "unprognostic (2.08e-2)" "unprognostic (8.06e-2)" "unprognostic (9.35e-2)" "unprognostic (2.45e-1)" "unprognostic (3.99e-2)" "prognostic favorable (1.93e-8)" "unprognostic (1.06e-1)" "unprognostic (3.73e-2)" "unprognostic (1.70e-1)" "unprognostic (3.89e-2)" 7.0 11.2 8.6 6.2 9.0 2.2 10.0 8.8 10.5 6.5 9.2 10.8 9.6 7.5 12.5 9.6 9.3 4.6 13.2 8.5 8.9 12.3 16.3 5.8 8.6 8.6 8.7 8.5 8.9 12.4 9.5 7.2 8.8 7.5 11.2 5.0 8.3 7.2 18.5 8.3 9.7 7.5 8.6 9.9 9.5 7.8 8.9 7.9 7.6 21.3 10.7 7.5 6.5 9.2 10.4 16.1 11.8 15.1 19.8 10.5 11.2 11.8 12.1 15.2 12.5 15.9 17.1 31.9 9.8 8.7 10.4 19.8 21.2 16.8 17.3 18.7 20.4 13.4 22.3 34.1 22.0 15.1 10.3 12.7 27.8 16.7 24.4 12.5 14.0 25.9 23.3 17.1 9.0 28.3 11.7 14.7 15.0 22.0 13.9 24.4 15.5 35.3 16.3 8.8 18.1 17.3 16.2 22.7 14.3 12.0 27.1 12.0 8.9 10.8 15.1 27.0 9.9 15.6 17.6 15.5 16.8 27.1 8.8 9.9 8.7 6.8 7.5 8.6 10.0 13.1 8.1 8.8 9.1 11.5 13.7 10.9 4.1 9.1 13.3 7.0 11.7 7.4 8.6 9.0 8.8 10.5 8.5 8.9 8.6 8.7 8.8 8.6 8.9 9.2 3.4 6.4 6.7 2.6 6.7 8.2 7.1 16.1 5.7 6.9 7.3 6.6 2.7 10.0 13.1 11.0 0.0 23.4 4.4 7.8 21.5 15.1 44.8 4.8 6.0 5.6 13.8 8.2 1.9 11.2 13.3 5.7 6.1 5.0 7.0 9.6 6.1 12.8 13.2 13.5 1.5 9.4 12.2 4.9 4.7 106.9 9.3 2.5 7.2 1.0 9.9 10.8 11.3 1.5 1.9 9.9 6.7 6.4 5.1 9.8 14.8 21.9 9.3 5.6 13.1 6.6 5.3 21.3 11.9 9.5 9.5 15.1 5.0 11.0 16.0 5.8 TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" 17.7 18.1 4.8 9.5 5.5 5.3 14.0 5.3 6.5 15.5 5.3 13.5 8.4 16.6 6.9 11.6 14.8 7.4 10.2 4.6 5.4 12.7 12.9 12.0 10.5 6.0 5.5 15.0 14.5 10.3 15.2 5.9 5.8 13.0 6.0 6.5 10.9 6.8 9.2 8.9 11.8 8.3 5.7 16.6 13.2 5.6 5.1 8.4 10.9 5.7 7.0 13.8 13.2 6.3 12.5 24.0 14.9 18.2 13.5 18.6 9.0 12.2 9.2 9.3 12.0 2.5 35.9 15.6 29.9 7.5 14.2 14.2 9.4 11.6 12.2 22.0 13.5 35.1 6.1 10.0 13.3 11.1 12.6 14.7 15.2 16.5 19.6 14.9 13.7 19.1 14.4 19.4 16.2 6.4 2.9 23.3 12.2 34.0 22.6 16.3 18.0 12.0 8.3 12.3 12.9 19.4 16.6 6.6 9.1 8.7 31.3 15.7 17.6 11.4 10.3 13.4 13.5 11.1 10.1 12.9 9.1 22.9 20.3 43.7 40.1 17.4 21.6 31.6 18.7 29.6 20.5 20.5 47.4 23.9 17.2 20.4 15.7 32.5 30.9 41.1 20.5 27.0 4.8 5.5 5.3 6.5 4.6 5.4 6.0 5.5 5.8 5.7 5.1 6.3 21.0 19.2 13.4 7.8 17.8 12.1 19.6 34.6 19.4 7.0 22.1 24.6 8.1 15.7 16.6 14.7 0.0 28.0 18.1 5.7 27.4 20.5 3.4 23.1 22.4 15.8 10.8 14.5 4.4 16.2 18.4 21.1 8.6 10.6 3.8 22.2 18.5 15.1 42.2 23.5 7.4 11.7 20.3 21.0 17.5 1.9 10.2 21.9 17.8 14.0 26.0 26.0 18.6 9.5 11.2 13.1 3.9 16.6 15.8 9.4 8.5 19.7 29.4 12.4 26.3 16.7 18.3 16.6 13.8 18.0 14.2 9.7 14.5 27.0 13.7 16.6 TMEM222 "C1orf160, DKFZP564D0478" ENSG00000186501 "Transmembrane protein 222" Q9H0R3 1 27322145-27336400 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016579, HPA059374" Approved Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "Cell Junctions" "HPA016579: AB_2669392, HPA059374: AB_2683995" "unprognostic (3.65e-1)" "unprognostic (5.27e-2)" "unprognostic (1.08e-1)" "unprognostic (1.39e-3)" "unprognostic (1.52e-1)" "unprognostic (1.33e-1)" "unprognostic (4.11e-2)" "unprognostic (1.16e-1)" "unprognostic (2.51e-2)" "unprognostic (1.96e-2)" "unprognostic (2.62e-2)" "unprognostic (1.45e-1)" "unprognostic (3.29e-3)" "unprognostic (5.28e-2)" "unprognostic (1.56e-1)" "unprognostic (3.83e-2)" "unprognostic (7.80e-2)" 26.6 38.2 61.9 13.0 60.1 23.8 27.1 58.7 76.8 25.1 57.4 26.9 15.0 28.1 24.4 36.1 29.6 19.2 34.5 61.2 65.4 32.8 49.4 22.4 16.1 61.7 64.4 26.6 28.6 30.6 38.4 13.0 62.3 39.0 14.4 10.6 26.7 23.9 36.8 28.9 23.8 18.8 60.7 25.0 30.1 28.8 63.8 21.1 29.4 20.7 14.1 27.6 24.2 59.5 26.2 31.2 25.7 42.3 39.2 28.2 20.7 39.6 45.1 52.9 44.8 13.0 53.5 16.5 30.2 42.4 24.6 35.3 28.3 38.5 21.9 22.0 54.4 27.6 24.7 30.1 58.0 27.8 26.5 49.4 21.5 50.8 28.7 24.3 35.7 32.4 21.2 37.1 33.6 23.4 40.1 29.2 48.3 27.0 38.6 32.8 17.7 33.5 51.6 15.2 54.8 48.4 30.6 42.6 39.7 9.2 42.3 44.2 33.1 31.1 26.1 50.6 38.1 39.8 38.5 17.6 47.1 53.3 45.8 38.2 20.6 27.7 32.5 32.5 24.8 37.4 29.7 24.6 18.5 30.0 29.1 30.2 56.3 31.9 35.3 30.4 37.4 25.6 61.9 60.1 58.7 76.8 61.2 65.4 61.7 64.4 62.3 60.7 63.8 59.5 22.9 9.6 13.5 8.5 25.4 11.7 13.3 26.2 15.9 42.1 24.0 29.2 8.9 18.6 13.3 12.9 14.6 30.9 20.9 24.5 39.2 39.1 25.5 13.2 17.2 20.6 29.9 43.8 12.4 40.5 33.9 22.6 18.8 12.4 17.1 22.0 11.0 15.1 28.3 43.7 15.0 21.0 40.7 8.5 12.9 76.9 20.2 12.2 26.6 6.5 20.6 51.9 22.6 17.1 14.4 48.6 22.7 19.9 18.6 19.9 28.8 19.2 7.9 18.7 13.1 19.6 20.3 27.2 18.0 19.3 13.5 30.8 20.5 22.4 23.1 12.4 TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.6;intestine: 8.4;testis: 5.3" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Bipolar cells: 3.7;Oligodendrocytes: 11.4;Proximal enterocytes: 10.0" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "SH-SY5Y: 130.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA056391: AB_2683114" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.89e-2)" "unprognostic (8.21e-2)" "unprognostic (4.74e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 0.0 1.0 7.5 0.0 11.0 0.0 0.0 9.8 9.0 0.1 2.5 0.1 8.4 0.1 0.4 0.0 0.6 0.0 0.2 7.7 9.6 0.0 0.0 0.0 0.0 9.1 12.6 0.2 0.0 0.8 0.9 0.1 9.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 3.9 0.1 7.9 0.1 1.8 5.3 10.2 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 130.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 11.0 9.8 9.0 7.7 9.6 9.1 12.6 9.0 7.9 10.2 11.7 0.0 0.0 0.0 9.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.2 0.0 2.0 11.4 0.0 2.5 0.0 0.0 0.1 10.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 1.2 0.7 0.2 TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA023892: AB_1845828" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (9.58e-2)" "unprognostic (1.63e-1)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.46e-9)" "unprognostic (6.11e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (2.24e-2)" 29.2 47.6 18.1 12.4 19.4 7.3 20.2 16.8 19.4 21.0 32.6 22.9 12.6 27.3 26.1 23.1 29.2 19.2 43.1 19.6 21.4 45.9 25.2 28.7 15.1 17.3 19.6 45.3 24.6 65.1 11.3 29.1 17.8 25.5 16.9 27.7 26.2 33.9 35.4 14.2 15.9 34.2 20.6 17.9 17.8 16.8 22.0 17.0 74.2 39.2 11.6 18.9 11.9 18.4 32.3 42.2 30.5 10.3 69.9 39.9 67.0 45.4 35.0 47.9 37.6 56.9 62.9 28.9 45.3 34.7 46.4 49.5 39.1 29.2 56.2 37.8 16.8 36.0 32.2 33.7 30.5 27.5 27.2 42.9 29.2 46.7 42.8 51.5 40.7 31.5 24.4 31.2 55.1 21.2 36.8 12.6 33.9 43.2 37.5 20.8 60.3 18.0 50.8 31.0 16.8 16.4 30.0 29.6 30.2 44.9 39.6 15.4 44.9 37.0 27.7 34.9 52.4 20.6 56.9 9.2 51.5 14.5 54.9 4.4 1.6 1.5 2.4 1.1 2.9 1.5 4.0 3.4 1.6 2.1 5.2 3.6 0.6 3.3 2.4 2.2 4.3 1.8 18.1 19.4 16.8 19.4 19.6 21.4 17.3 19.6 17.8 20.6 22.0 18.4 55.0 115.4 93.1 36.6 22.4 25.2 18.8 27.4 27.3 43.8 34.4 23.0 135.6 74.4 33.8 86.5 106.3 50.7 20.1 27.0 3.9 22.7 6.7 31.6 24.8 51.8 31.2 70.5 71.4 31.1 17.7 31.3 25.5 56.4 31.6 62.8 74.3 98.3 18.0 63.9 62.0 31.1 10.2 28.4 14.3 7.8 41.0 18.9 23.2 46.9 18.3 52.6 16.5 60.8 75.8 30.0 35.6 51.1 19.7 23.1 55.3 33.7 45.6 32.4 46.0 40.7 37.9 27.4 43.8 21.0 28.4 15.1 28.2 81.4 35.6 21.7 TMEM251 "C14orf109, DKFZP564F1123" ENSG00000153485 "Transmembrane protein 251" Q8N6I4 14 93184951-93188463 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal tubular cells: 113.5;Hofbauer cells: 110.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048559 Uncertain Approved "Golgi apparatus,Cell Junctions" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 4: Macrophages - Innate immune response" "Cell Junctions" "Golgi apparatus" "HPA048559: AB_2680441" "unprognostic (1.21e-2)" "unprognostic (4.56e-2)" "unprognostic (4.61e-3)" "unprognostic (3.37e-2)" "unprognostic (2.14e-1)" "unprognostic (4.03e-2)" "prognostic unfavorable (6.14e-7)" "unprognostic (1.67e-2)" "unprognostic (1.88e-1)" "unprognostic (9.99e-3)" "unprognostic (5.80e-3)" "unprognostic (1.58e-1)" "prognostic favorable (1.10e-4)" "unprognostic (5.17e-2)" "unprognostic (1.61e-1)" "unprognostic (7.47e-2)" "unprognostic (6.17e-2)" 16.6 22.9 7.3 6.4 7.8 2.7 16.9 7.9 10.0 15.5 8.2 22.9 10.3 14.2 16.5 13.1 14.7 6.7 25.6 7.6 7.6 33.2 17.2 17.1 8.0 7.7 7.8 14.2 21.2 10.3 19.8 6.9 7.8 25.7 12.5 20.7 19.6 9.2 30.6 13.7 18.1 6.8 7.4 15.9 21.8 8.4 8.1 8.6 17.6 12.4 6.9 17.2 12.8 9.0 11.0 12.1 15.3 16.1 17.2 7.3 9.4 7.9 8.2 12.7 16.2 7.8 11.1 12.1 12.9 7.9 15.9 15.9 17.8 12.6 17.7 9.3 13.4 10.9 8.8 18.3 15.2 16.0 14.7 9.3 14.6 10.0 16.2 6.8 12.2 13.5 9.3 12.0 11.6 52.5 10.2 12.8 8.3 28.0 11.6 4.7 16.0 11.3 16.6 23.6 12.9 13.4 11.7 6.0 36.9 12.4 17.7 11.4 5.0 6.1 10.8 14.6 9.4 9.3 16.0 11.8 11.4 6.1 9.1 6.8 9.7 13.6 3.9 9.4 2.9 4.7 4.6 4.4 8.0 5.5 5.2 5.9 10.5 5.3 13.0 7.3 4.1 4.2 7.3 7.8 7.9 10.0 7.6 7.6 7.7 7.8 7.8 7.4 8.1 9.0 13.4 3.2 14.4 5.2 22.4 23.2 37.9 33.6 13.1 14.8 41.1 39.1 22.5 32.9 22.0 31.3 27.1 36.6 16.5 44.8 113.5 30.3 1.8 33.1 16.3 11.9 15.0 11.3 5.9 26.6 21.1 16.6 20.9 35.7 17.2 15.2 8.9 19.2 110.1 13.5 7.8 36.1 26.4 28.4 20.0 2.3 11.8 39.6 32.0 2.8 16.2 34.8 12.3 5.0 13.8 17.7 23.8 10.9 13.1 43.3 31.7 69.6 17.2 30.6 39.5 13.9 23.2 4.5 17.8 18.1 31.1 27.4 16.1 17.6 30.9 36.4 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM258 "C11orf10, Kud, Kuduk" ENSG00000134825 "Transmembrane protein 258" P61165 11 61768501-61792802 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044602 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "HPA044602: AB_10961423" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (7.49e-2)" "unprognostic (4.99e-3)" "unprognostic (9.95e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.24e-1)" "unprognostic (8.48e-2)" "prognostic favorable (4.37e-4)" "unprognostic (1.34e-3)" "unprognostic (7.39e-2)" "unprognostic (4.75e-3)" "unprognostic (2.59e-2)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.58e-1)" 116.4 158.4 125.5 66.1 128.7 128.4 120.8 130.8 162.2 142.2 123.0 112.4 80.9 116.0 350.1 122.8 123.1 59.3 170.8 122.6 128.7 123.5 160.6 110.0 83.0 130.0 125.6 154.9 300.3 80.5 128.9 80.4 130.3 105.5 107.6 44.0 183.9 88.7 146.7 95.3 99.8 81.5 131.1 124.4 142.8 79.1 126.8 111.7 109.1 120.6 108.9 107.5 111.7 140.1 144.3 254.9 194.9 173.3 329.0 308.4 117.1 113.9 177.1 104.5 124.8 223.5 265.5 103.9 205.9 272.1 196.1 154.8 186.7 222.7 149.1 141.7 168.6 86.8 258.3 347.6 310.7 186.9 96.3 272.5 339.6 137.1 364.8 267.9 210.9 207.4 221.7 394.5 185.4 501.1 131.2 318.8 267.1 315.6 172.9 142.1 144.6 673.0 241.5 243.7 169.3 173.1 103.8 221.7 211.5 179.6 244.5 347.3 108.0 129.2 111.7 166.1 78.3 248.6 201.7 173.6 183.8 112.6 135.7 507.9 225.6 287.6 169.5 200.4 216.5 233.2 198.8 190.1 177.8 187.1 167.1 166.7 182.4 151.7 204.4 496.4 236.8 244.9 125.5 128.7 130.8 162.2 122.6 128.7 130.0 125.6 130.3 131.1 126.8 140.1 211.3 102.5 224.1 6.8 323.6 228.9 220.5 794.5 170.8 41.3 525.1 608.3 491.3 403.2 445.9 318.2 18.8 409.5 279.8 306.2 295.4 534.8 234.4 369.2 304.7 254.8 311.1 197.7 7.4 654.4 667.7 314.8 210.5 305.6 226.7 261.8 335.2 572.9 461.4 37.0 8.2 631.5 441.5 401.7 396.9 142.8 335.5 265.7 569.2 3.7 430.0 418.6 270.8 6.0 25.8 469.4 432.6 214.4 821.3 296.6 392.2 553.8 470.9 73.9 170.9 192.3 248.5 399.4 433.8 297.4 279.0 508.0 245.2 135.3 442.1 274.9 TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.4;skeletal muscle: 5.8;tongue: 2.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Cytotrophoblasts: 16.0;Early spermatids: 7.0;Late spermatids: 19.7;Rod photoreceptor cells: 9.1;Sertoli cells: 6.6;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.3" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in many" 5 "cerebellum: 26.8" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" 0.0 0.9 0.9 0.0 1.0 0.0 0.1 8.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.5 0.0 0.5 0.1 0.6 0.8 0.0 1.1 0.0 1.2 0.9 0.7 0.1 0.0 1.1 0.0 0.0 5.8 0.5 0.0 0.0 0.5 0.1 0.0 0.6 1.4 0.3 0.0 2.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 8.4 1.7 1.2 0.9 0.6 0.8 0.7 0.5 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 4.3 0.5 0.5 0.0 0.0 0.0 1.8 10.4 16.0 0.0 0.0 1.9 0.0 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.2 2.2 0.9 1.5 0.1 0.0 0.2 0.4 0.4 4.5 1.7 0.0 0.0 0.0 0.3 0.0 19.7 0.0 0.4 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.0 0.0 0.7 1.5 9.1 6.6 1.3 0.2 0.5 6.3 0.0 0.0 5.9 0.2 0.5 0.0 0.7 TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 10.3;Breast glandular cells: 8.8;Endometrial stromal cells: 8.9;Glandular and luminal cells: 8.8;Granulosa cells: 9.6;Hofbauer cells: 8.9;monocytes: 19.1;Syncytiotrophoblasts: 8.8;Theca cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 7.3 7.7 11.0 6.9 12.7 3.6 7.5 2.9 16.6 6.5 6.4 6.9 3.4 6.8 6.3 4.3 4.7 3.7 3.3 14.4 6.1 3.3 5.3 5.2 9.5 4.4 5.3 8.5 4.7 14.1 4.1 4.8 5.3 12.2 5.4 4.5 8.9 6.5 4.6 4.2 6.3 6.8 5.3 13.3 7.2 3.9 6.5 8.6 6.2 4.3 9.4 6.3 5.1 11.3 4.7 7.1 3.8 8.2 10.1 7.6 2.9 4.3 7.9 6.0 6.1 5.1 2.0 19.5 3.5 4.8 17.0 8.1 7.4 3.7 5.2 9.9 4.6 6.5 5.8 4.0 17.9 13.6 3.0 6.7 6.5 7.8 8.4 7.7 4.1 24.9 12.3 51.5 4.4 13.6 15.4 4.5 9.8 6.0 7.8 17.4 4.5 17.7 3.5 3.4 12.5 8.4 14.4 18.8 41.3 2.4 25.2 12.2 2.5 6.0 6.8 2.3 8.3 27.8 27.5 20.7 3.1 11.4 11.0 0.3 1.3 0.2 0.6 1.0 0.2 1.3 0.7 0.4 0.7 2.2 0.9 0.8 1.0 0.8 1.0 4.7 0.1 0.5 11.0 12.7 2.9 16.6 14.4 6.1 4.4 5.3 5.3 5.3 6.5 11.3 1.7 0.0 10.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 5.2 0.0 0.0 1.3 0.0 0.0 4.7 3.0 0.0 0.0 1.4 0.0 5.0 8.9 0.5 0.0 0.0 0.0 4.6 1.2 1.3 0.0 8.8 0.0 9.6 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 19.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 1.9 4.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.8 1.1 9.7 0.0 0.0 TMEM50A SMP1 ENSG00000183726 "Transmembrane protein 50A" O95807 1 25338317-25362361 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065192 Approved "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Actin filaments, Cytosol" "HPA065192: AB_2685429" "unprognostic (2.41e-2)" "unprognostic (2.74e-1)" "unprognostic (5.17e-3)" "prognostic favorable (8.64e-5)" "unprognostic (1.45e-1)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.34e-4)" "unprognostic (7.39e-2)" "unprognostic (7.92e-3)" "unprognostic (2.53e-1)" "unprognostic (1.02e-2)" "unprognostic (2.44e-2)" "unprognostic (2.39e-3)" "unprognostic (6.66e-2)" "unprognostic (2.91e-1)" "unprognostic (3.91e-3)" "unprognostic (3.44e-2)" 47.2 63.0 43.9 44.5 47.8 41.8 55.5 45.3 55.8 47.0 43.7 58.5 49.6 35.7 53.0 36.5 38.4 45.7 44.2 45.0 44.4 55.0 33.4 58.1 52.2 46.5 44.4 26.2 32.6 49.5 14.6 57.7 46.4 54.4 65.7 45.4 81.5 52.7 16.9 41.1 55.4 46.0 47.2 46.9 49.5 16.1 45.5 47.1 47.0 26.5 47.3 55.1 29.8 50.4 43.3 44.6 74.3 42.3 132.9 119.8 28.1 89.0 123.6 143.4 159.5 36.5 110.9 50.2 47.9 274.6 55.7 62.6 56.3 61.9 161.2 126.1 81.4 104.7 47.5 55.2 96.5 82.4 80.3 128.0 91.4 106.1 60.5 69.7 107.0 50.8 73.1 79.5 140.9 30.6 53.2 90.2 90.6 73.7 37.1 45.7 85.3 88.9 148.8 30.9 64.5 42.3 89.0 64.2 72.2 69.3 32.7 52.0 171.0 86.5 36.6 144.9 36.8 52.3 61.5 45.0 117.1 117.2 50.3 275.5 76.9 109.8 87.9 94.7 91.9 49.6 77.2 91.1 55.9 40.9 55.1 76.6 159.2 80.5 117.3 51.9 95.4 106.3 43.9 47.8 45.3 55.8 45.0 44.4 46.5 44.4 46.4 47.2 45.5 50.4 244.8 144.2 84.2 21.2 107.9 253.4 184.5 392.3 146.8 43.9 162.0 164.8 105.6 102.9 212.7 169.2 27.1 108.9 191.0 175.6 50.9 300.3 25.4 136.4 119.3 203.3 83.0 93.6 31.6 215.6 312.5 198.1 91.3 180.8 126.6 58.2 152.0 68.3 227.1 25.2 27.3 170.7 309.3 162.4 245.1 12.7 151.9 223.8 199.3 16.9 253.8 102.0 154.5 28.1 48.8 315.3 164.8 98.9 168.2 340.6 120.0 113.1 205.1 41.7 210.4 71.6 200.6 94.7 47.0 166.8 317.7 181.6 180.9 116.9 106.9 274.3 TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "pancreas: 216.2;skeletal muscle: 298.9;tongue: 207.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 22.3;Hepatocytes: 25.9;Spermatocytes: 34.6;Spermatogonia: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 20.5;OE19: 18.2;RPMI-8226: 37.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA079372: " "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (7.35e-3)" "unprognostic (1.04e-5)" "unprognostic (1.46e-1)" "unprognostic (6.71e-3)" "unprognostic (3.68e-2)" "unprognostic (9.49e-2)" "unprognostic (1.69e-1)" "unprognostic (3.83e-3)" "unprognostic (5.80e-2)" "unprognostic (8.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" 1.9 52.6 1.9 0.2 2.1 0.5 2.0 2.1 3.7 1.1 3.0 2.5 3.6 0.6 0.4 6.9 3.3 0.4 1.8 1.8 1.9 2.4 13.5 1.9 0.4 1.8 2.1 2.2 216.2 3.1 1.7 0.2 1.7 1.8 1.3 0.2 19.8 0.4 298.9 3.5 2.3 0.3 1.5 2.8 6.9 29.2 1.8 0.4 0.8 207.8 0.3 0.6 2.1 1.7 3.4 0.3 0.9 1.8 0.3 0.1 7.5 0.5 0.2 2.2 1.3 5.6 2.3 0.8 2.2 3.5 0.8 1.1 5.5 1.5 0.4 0.4 4.0 0.0 0.9 20.5 1.1 0.0 1.3 0.1 3.1 0.7 0.3 0.1 0.1 3.9 5.1 1.9 0.0 6.4 0.5 1.5 2.9 18.2 10.6 1.5 0.0 37.1 1.2 0.2 3.7 2.6 0.0 3.1 0.4 1.3 2.1 0.4 0.0 0.0 1.4 1.0 0.0 2.4 0.8 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.1 2.1 3.7 1.8 1.9 1.8 2.1 1.7 1.5 1.8 1.7 0.4 0.0 0.0 0.0 1.2 4.5 2.9 1.2 2.8 0.4 3.9 5.2 0.8 8.6 2.4 0.0 0.0 1.9 0.8 6.8 1.9 1.8 3.9 3.8 0.3 0.8 0.0 0.4 0.6 22.3 7.0 1.6 5.1 0.8 0.0 5.1 0.7 25.9 0.6 0.0 0.5 11.1 8.2 0.8 2.2 5.8 14.9 0.7 8.8 0.0 0.6 1.8 0.0 0.0 0.1 6.7 2.5 9.8 4.3 14.2 15.4 11.5 8.7 1.0 0.0 15.4 1.6 34.6 39.4 2.5 2.8 3.7 1.2 15.5 7.1 3.1 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 512 "intestine: 979.8" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 28.0" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "U-138 MG: 50.8;U-87 MG: 141.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.0;spinal cord: 1.8" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA015611: AB_1855791, HPA034857: , HPA072934: AB_2732214" "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.0 0.0 0.9 0.2 0.7 0.0 0.0 1.9 1.7 0.0 0.0 0.2 979.8 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.6 0.0 0.0 0.0 0.7 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 21.8 0.0 0.0 0.0 0.4 1.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 4.6 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 0.0 0.3 0.0 0.9 0.0 0.2 141.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.7 1.9 1.7 0.7 0.6 0.2 0.6 0.1 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 4.0 0.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 60.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 2152.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;WM-115: 80.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Actin filaments" "HPA026954: AB_2256025, HPA026955: AB_10602282" "unprognostic (1.56e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" "unprognostic (7.38e-2)" "unprognostic (2.60e-2)" "unprognostic (3.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.16e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-2)" "prognostic favorable (2.84e-5)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.06e-2)" "unprognostic (8.06e-2)" 3.7 0.8 11.4 4.7 39.8 2.1 4.6 21.4 25.1 4.8 0.0 11.7 2.8 5.4 4.4 9.8 10.0 7.8 2.0 11.2 19.1 6.6 1.2 6.4 1.8 28.3 29.9 1.9 4.5 2.8 3.5 3.4 26.7 6.1 5.7 5.5 6.9 11.2 1.2 5.2 4.7 6.8 11.7 1.3 10.2 3.0 26.8 1.5 6.4 1.7 2.2 7.5 7.3 60.8 1.7 6.4 32.0 0.2 4.3 3.9 2.9 2.1 0.7 1.7 0.3 0.3 3.4 0.0 0.5 11.9 1.2 2.8 9.7 4.9 0.5 7.5 5.8 0.0 5.2 0.2 0.4 2.2 1.0 1.1 4.3 0.2 1.6 3.4 2.7 3.5 0.0 4.2 0.4 3.4 1.6 8.8 1.1 6.0 5.3 0.0 1.3 0.6 2.9 14.1 8.3 15.1 2.9 4.6 21.0 5.4 4.9 0.5 1.7 5.3 1.8 7.2 2.7 7.8 5.7 1.2 1.2 3.8 80.2 0.0 0.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 11.4 39.8 21.4 25.1 11.2 19.1 28.3 29.9 26.7 11.7 26.8 60.8 10.7 9.6 8.9 333.3 2.0 14.4 15.5 12.0 18.2 38.1 8.9 5.5 1.8 11.5 18.4 14.7 8.4 13.6 3.1 3.6 0.0 5.4 12.9 13.5 7.5 10.3 2.4 0.8 117.1 8.2 1.7 9.8 12.8 13.1 0.0 0.2 2.5 1.4 1.9 8.4 377.0 9.8 2.0 6.6 9.6 5.0 5.9 6.2 32.0 86.2 9.3 13.9 1.0 38.7 2152.4 9.4 3.3 1.2 7.3 11.9 2.7 2.1 17.0 1.6 6.6 0.8 2.2 0.6 2.2 16.2 11.5 4.1 2.8 1.0 5.9 14.5 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 612.4;Basal prostatic cells: 1315.6;Basal respiratory cells: 622.2;Ductal cells: 938.2;Exocrine glandular cells: 698.4;Pancreatic endocrine cells: 1232.3;Prostatic glandular cells: 757.9;Urothelial cells: 695.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 139.6;neutrophil: 102.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 139.6" "Cell line enhanced" "Detected in many" "U-251 MG: 699.6" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" 42.0 45.9 5.3 27.0 5.2 8.3 24.4 6.1 9.9 12.5 9.4 26.5 37.5 34.8 1.2 17.6 19.0 55.2 108.3 5.6 8.8 133.5 61.0 72.6 2.4 8.2 7.9 8.2 116.3 56.1 59.3 33.0 7.0 33.4 4.5 4.8 48.4 17.1 58.5 18.1 21.6 32.5 7.4 6.7 42.6 5.4 10.4 5.2 37.0 9.3 3.1 73.8 13.9 7.0 217.6 155.6 17.7 31.9 31.0 71.3 109.1 444.3 277.5 316.2 205.5 70.1 336.0 1.5 566.2 270.4 401.3 224.2 4.2 283.4 132.2 8.3 11.2 1.5 52.4 58.4 205.1 3.7 15.2 65.2 196.7 345.1 433.5 298.1 100.9 0.6 24.5 2.4 362.7 394.0 0.6 28.3 85.5 88.7 369.6 1.9 207.1 7.8 355.8 37.6 19.9 7.3 314.7 127.9 255.8 57.7 69.4 5.8 192.2 601.9 303.2 423.8 699.6 6.6 2.9 3.1 190.0 18.9 488.8 12.2 11.4 139.6 6.1 7.3 7.9 0.2 2.8 4.9 14.6 0.2 1.4 2.7 102.9 8.0 4.7 0.6 3.4 4.0 5.3 5.2 6.1 9.9 5.6 8.8 8.2 7.9 7.0 7.4 10.4 7.0 16.9 102.5 37.7 0.3 6.9 612.4 1315.6 622.2 113.3 1.5 139.0 46.7 63.9 195.9 238.7 182.1 2.1 134.6 10.0 74.2 64.6 938.2 1.3 170.5 29.4 47.5 27.3 1.3 0.2 698.4 169.5 155.1 33.1 173.1 59.1 3.0 24.3 20.7 39.7 0.0 0.5 19.9 152.5 5.6 121.4 0.8 6.2 23.0 112.1 1.9 10.8 23.3 4.1 0.0 0.1 1232.3 155.3 6.8 5.3 757.9 52.9 118.0 118.4 5.9 6.6 190.5 228.6 10.9 9.4 35.5 359.7 189.1 25.3 1.3 50.0 695.6 TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 148.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 179.9;Prostatic glandular cells: 180.8;Syncytiotrophoblasts: 178.7;Urothelial cells: 387.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.2" "Lineage enriched" "Detected in single" 303 "dendritic cells: 69.2" "Cell line enhanced" "Detected in many" "OE19: 208.0;RT4: 523.8;SuSa: 213.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" 55.7 6.6 17.6 17.7 31.0 13.4 13.4 48.9 31.4 17.5 1.1 38.1 12.3 17.1 2.5 41.3 16.4 35.7 9.8 21.8 27.4 49.6 8.9 16.9 17.2 76.8 43.8 6.5 20.0 58.8 6.5 33.2 56.9 13.7 34.8 4.1 25.6 4.0 6.0 4.0 19.2 15.7 43.7 14.9 60.8 8.1 49.0 26.8 4.0 14.1 32.9 148.1 17.1 100.1 156.6 50.0 47.7 15.3 127.4 37.5 53.9 17.9 34.9 5.5 2.1 86.7 107.7 11.6 70.3 13.1 101.8 92.2 7.2 66.1 3.1 0.2 15.1 0.1 6.4 88.2 74.6 2.5 0.6 67.1 77.2 3.3 58.1 4.2 25.8 10.1 3.8 0.1 1.9 30.8 13.9 1.4 37.5 208.0 50.8 29.1 14.7 17.1 90.8 523.8 34.1 7.5 15.6 14.4 12.9 213.0 11.1 11.0 5.2 14.1 12.9 0.5 16.5 0.1 0.2 16.1 23.1 11.1 40.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.1 0.1 0.1 69.2 0.0 0.6 17.6 31.0 48.9 31.4 21.8 27.4 76.8 43.8 56.9 43.7 49.0 100.1 5.5 0.0 9.8 1.6 3.1 23.7 179.9 140.5 64.9 1.1 8.0 10.8 10.2 35.8 59.9 1.8 0.0 31.0 77.3 100.7 15.6 86.8 55.0 12.0 17.3 8.6 12.0 3.0 46.6 29.6 21.4 32.9 80.5 13.8 19.7 2.1 1.1 0.3 22.4 0.0 29.6 42.9 107.8 53.6 12.5 40.3 2.8 22.6 12.4 13.1 0.6 5.4 0.0 53.3 44.7 89.1 54.5 1.2 2.0 180.8 14.7 51.3 54.7 1.4 78.9 21.5 24.2 1.0 3.7 40.4 9.9 178.7 2.8 13.1 19.9 387.3 TNFRSF25 "APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR" ENSG00000215788 "TNF receptor superfamily member 25" Q93038 1 6460786-6466175 "Predicted membrane proteins, Predicted secreted proteins" Apoptosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.0;pituitary gland: 29.9;skin 1: 25.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 34.1;Excitatory neurons: 37.5;T-cells: 41.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "MAIT T-cell: 5.6;memory CD4 T-cell: 4.4;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.4;T-reg: 7.9" "Lineage enriched" "Detected in many" 7 "T-cells: 7.9" "Cell line enhanced" "Detected in many" "HDLM-2: 20.5;RPMI-8226: 25.7" "Group enriched" "Detected in some" 6 "amygdala: 1.2;cerebral cortex: 1.4;hippocampal formation: 2.0" "Not detected" "Not detected" HPA069834 Approved "Nucleoplasm,Plasma membrane,Actin filaments,Focal adhesion sites" "Secreted - unknown location" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Actin filaments, Focal adhesion sites" Nucleoplasm "HPA069834: " "unprognostic (8.09e-3)" "unprognostic (6.91e-3)" "prognostic unfavorable (4.46e-4)" "unprognostic (1.97e-1)" "unprognostic (9.63e-3)" "prognostic favorable (3.09e-4)" "unprognostic (2.16e-1)" "unprognostic (1.46e-1)" "unprognostic (2.04e-1)" "unprognostic (2.07e-1)" "unprognostic (6.01e-2)" "unprognostic (3.98e-2)" "prognostic unfavorable (1.65e-7)" "unprognostic (1.21e-1)" "unprognostic (1.61e-1)" "unprognostic (3.44e-1)" "unprognostic (8.68e-3)" 6.4 4.2 4.0 3.2 4.0 0.8 4.0 11.1 6.1 5.2 4.9 6.1 3.0 3.0 0.6 10.3 5.7 2.2 8.7 4.8 4.3 3.3 1.2 2.4 4.3 3.7 3.6 3.1 1.5 0.9 29.9 4.4 4.4 5.2 1.4 1.2 3.3 2.3 1.1 25.3 5.0 0.5 3.3 44.0 2.0 0.9 3.7 2.0 3.2 1.2 2.7 2.5 4.6 3.5 1.8 0.4 1.1 2.0 0.0 0.6 1.3 1.5 0.6 0.3 0.0 1.7 2.8 0.0 2.5 0.0 1.3 4.2 0.6 4.7 0.0 20.5 1.5 0.6 1.7 0.1 0.7 0.0 0.1 0.0 3.2 1.5 4.1 2.7 4.0 1.1 0.0 0.0 0.0 2.2 0.0 8.0 1.4 1.4 3.4 0.6 0.3 25.7 1.3 0.7 3.4 5.3 0.0 2.5 0.1 0.6 2.0 2.9 2.5 1.3 2.1 0.0 2.0 0.0 3.5 0.0 2.4 0.0 0.0 0.0 0.0 0.0 1.0 0.2 5.6 0.0 4.4 2.2 0.5 0.0 4.4 0.7 0.0 0.8 1.0 0.0 7.9 0.9 4.0 4.0 11.1 6.1 4.8 4.3 3.7 3.6 4.4 3.3 3.7 3.5 19.0 3.2 5.0 3.9 2.5 24.6 2.3 5.6 11.4 3.1 4.2 5.5 1.1 1.5 3.3 1.8 2.1 0.7 12.8 34.1 0.0 0.2 0.2 4.1 11.2 11.5 6.7 3.0 37.5 0.4 2.0 2.3 5.6 6.9 7.0 4.8 7.9 1.1 4.0 5.0 21.6 20.3 0.0 1.2 6.6 0.3 2.8 4.0 7.2 14.0 3.0 10.2 10.3 7.5 2.1 1.4 16.0 9.4 3.2 3.7 9.8 0.6 4.8 9.1 0.0 2.6 2.6 0.4 1.2 8.6 28.6 0.1 41.4 0.7 25.0 6.8 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "dendritic cells: 15.0;granulocytes: 63.4;Langerhans cells: 17.5;monocytes: 31.6;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 7.8;NK-cell: 5.2;T-reg: 18.5" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;NK-cells: 5.2;T-cells: 18.5" "Cell line enriched" "Detected in some" 9 "HDLM-2: 111.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Nucleoli "HPA071425: AB_2686394" "unprognostic (7.23e-2)" "unprognostic (1.72e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-4)" "unprognostic (9.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.69e-8)" "unprognostic (1.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (9.55e-2)" 0.5 0.2 0.4 3.9 0.4 2.2 0.2 1.1 0.5 0.2 0.3 0.5 0.5 0.3 0.2 0.6 0.1 1.6 0.2 0.4 0.1 0.2 0.7 0.8 9.0 0.3 0.1 0.2 0.7 0.0 0.0 0.2 0.3 0.3 1.1 0.5 0.3 0.2 0.2 0.5 0.8 0.2 0.0 4.1 0.8 0.2 0.3 3.7 0.2 0.2 9.9 1.9 0.0 1.1 2.5 0.9 0.2 0.2 0.0 0.1 0.1 0.1 0.4 0.5 0.5 3.1 0.5 0.1 1.2 0.1 1.8 0.4 0.0 0.4 1.9 111.5 0.2 0.6 0.5 0.1 1.8 0.0 0.9 0.3 0.7 0.5 0.2 0.4 0.1 0.1 0.4 0.3 0.1 0.2 0.0 0.3 0.1 0.1 0.2 0.1 0.7 0.2 0.3 0.1 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.3 0.3 0.3 3.2 0.1 0.5 0.2 0.2 0.2 13.0 0.8 0.1 1.5 1.9 0.2 1.7 0.6 0.3 0.3 1.1 9.4 1.4 0.4 0.2 1.7 7.8 5.2 0.1 0.3 18.5 1.4 0.4 0.4 1.1 0.5 0.4 0.1 0.3 0.1 0.3 0.0 0.3 1.1 0.6 0.0 1.7 0.0 1.6 0.3 0.9 0.3 0.6 0.0 0.3 0.5 0.4 0.0 1.9 0.0 0.0 0.0 15.0 0.1 0.0 1.3 0.0 0.6 1.0 0.8 0.0 0.0 0.2 1.1 0.0 1.0 3.6 1.4 63.4 0.0 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.3 17.5 0.0 0.0 3.6 5.4 0.0 31.6 0.0 1.0 0.0 0.1 2.0 0.1 0.0 9.4 0.5 0.0 0.1 0.0 0.0 0.0 7.7 1.0 0.4 0.1 0.1 0.4 0.0 29.2 0.0 0.5 0.3 TNFSF13B "BAFF, BLYS, CD257, TALL-1, TALL1, THANK, TNFSF20" ENSG00000102524 "TNF superfamily member 13b" Q9Y275 13 108251240-108308484 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" Immunity Cytokine "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in many" "Hofbauer cells: 87.5;Kupffer cells: 141.1;Langerhans cells: 246.7;Macrophages: 170.4;monocytes: 509.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 505.4" "Group enriched" "Detected in all" 11 "dendritic cells: 206.4;granulocytes: 505.4;monocytes: 350.9" "Cell line enriched" "Detected in some" 7 "U-937: 167.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB009188, HPA030526" Enhanced Supported "Vesicles,Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 393000 790000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Vesicles, Focal adhesion sites" "CAB009188: , HPA030526: " "unprognostic (6.48e-2)" "unprognostic (3.05e-3)" "unprognostic (1.38e-1)" "unprognostic (1.90e-1)" "unprognostic (2.61e-2)" "unprognostic (7.99e-2)" "unprognostic (8.19e-2)" "unprognostic (1.37e-1)" "unprognostic (1.63e-1)" "unprognostic (1.02e-2)" "unprognostic (2.64e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (2.53e-11)" "unprognostic (1.23e-1)" "unprognostic (4.14e-2)" "unprognostic (1.88e-1)" "unprognostic (1.25e-1)" 8.2 5.3 2.8 25.9 2.6 20.1 4.7 2.7 4.1 2.2 5.8 5.5 10.7 1.4 1.5 4.8 2.4 12.4 3.8 2.7 3.1 1.5 5.3 10.9 20.9 6.3 3.0 1.1 1.5 0.7 1.0 9.0 4.2 1.7 8.4 0.4 3.3 1.2 1.4 1.9 6.4 5.0 4.6 15.9 5.0 1.2 3.5 5.3 3.0 1.6 17.7 11.1 2.1 5.2 0.1 0.4 0.1 0.1 0.7 0.8 0.2 0.3 0.8 0.6 2.1 0.1 1.7 0.3 0.2 0.2 0.3 0.1 0.0 0.1 0.1 11.6 0.0 0.9 0.4 0.0 0.4 10.2 0.3 2.0 0.4 0.2 0.1 0.4 0.1 0.1 0.1 0.6 1.2 0.0 0.1 5.3 0.1 1.1 0.0 0.0 0.2 0.0 0.6 0.3 1.3 0.3 0.0 0.0 0.4 0.2 0.1 22.3 0.2 0.3 0.0 0.0 0.4 10.0 0.3 0.1 10.3 167.0 1.7 12.6 350.9 100.1 5.4 272.3 31.5 4.4 21.5 4.4 206.4 7.1 9.9 3.4 505.4 5.0 234.1 77.8 19.4 165.8 2.8 2.6 2.7 4.1 2.7 3.1 6.3 3.0 4.2 4.6 3.5 5.2 3.1 16.0 12.9 6.2 7.0 7.1 0.7 1.3 1.2 0.9 2.4 3.2 0.6 10.0 4.2 5.5 0.0 0.5 40.6 0.6 1.9 2.3 1.2 0.4 0.7 3.6 1.2 14.5 18.1 32.5 1.1 29.6 3.1 0.5 5.1 0.9 3.9 2.8 87.5 0.0 11.2 0.9 0.0 141.1 246.7 0.6 5.3 170.4 8.8 15.0 509.4 0.2 5.2 55.3 5.1 1.7 0.5 1.9 1.5 2.7 2.2 1.3 2.0 0.3 6.6 1.4 4.1 0.1 0.7 0.5 4.7 1.1 10.5 1.2 1.8 3.1 TNK1 KOS1 ENSG00000174292 "Tyrosine kinase non receptor 1" Q13470 17 7380534-7389774 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 13.1;Distal enterocytes: 13.9;Gastric mucus-secreting cells: 16.8;Proximal enterocytes: 11.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "cerebellum: 1.9" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 5.7;HaCaT: 9.1;HBEC3-KT: 6.0;hTCEpi: 6.6;T-47d: 7.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA012065, HPA056452" Uncertain Approved "Cell Junctions" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 35: Glandular cells - Unknown function" "Cell Junctions" "HPA012065: AB_1858165, HPA056452: " "unprognostic (4.90e-2)" "unprognostic (1.93e-1)" "unprognostic (2.95e-1)" "prognostic favorable (4.28e-4)" "unprognostic (2.84e-1)" "unprognostic (1.60e-1)" "unprognostic (1.41e-2)" "unprognostic (3.65e-1)" "unprognostic (2.20e-1)" "unprognostic (2.52e-2)" "unprognostic (2.43e-1)" "unprognostic (3.10e-1)" "prognostic favorable (6.40e-4)" "unprognostic (1.77e-3)" "unprognostic (1.61e-1)" "unprognostic (1.38e-1)" "prognostic favorable (1.52e-4)" 3.6 0.9 0.3 1.2 0.5 0.2 5.6 1.9 0.4 3.8 0.4 7.3 3.7 2.4 0.8 7.1 3.1 1.0 1.6 0.2 0.3 5.2 5.1 2.6 1.5 0.0 0.0 3.3 7.8 3.0 3.0 0.2 0.0 7.0 2.3 1.3 8.1 1.4 0.5 8.8 7.7 0.5 0.0 3.1 7.6 1.9 0.2 0.5 4.8 0.1 1.7 4.2 5.6 0.3 5.7 0.9 0.1 0.4 0.0 0.0 3.7 0.2 0.0 0.3 0.4 2.9 2.6 0.0 2.2 0.3 0.1 9.1 0.0 6.0 0.1 0.6 1.3 0.0 3.5 1.6 0.3 0.0 0.2 0.1 6.6 0.0 1.0 0.1 0.0 2.4 0.7 0.0 0.0 4.4 0.6 0.0 0.7 4.9 0.7 0.2 0.1 0.6 4.1 2.6 0.1 0.4 3.1 4.5 0.8 0.2 7.4 0.1 1.5 0.2 0.7 0.2 0.0 0.4 0.9 0.1 0.1 0.4 0.4 0.0 0.0 0.0 0.3 0.0 0.6 0.5 0.6 0.4 0.0 0.4 1.1 1.3 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.5 1.9 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.3 2.6 6.4 3.4 0.0 2.9 2.5 2.6 5.1 13.1 1.8 9.1 7.4 1.1 2.8 3.5 1.8 0.0 0.2 0.3 13.9 0.0 5.2 1.5 2.8 1.0 1.5 3.0 0.4 0.5 6.9 0.6 1.0 16.8 4.6 0.0 0.1 1.1 2.9 0.1 0.0 0.4 7.0 2.0 0.0 0.5 1.5 1.2 0.4 0.0 0.0 0.4 0.2 2.1 0.0 0.1 8.5 8.0 0.4 0.4 3.9 11.6 1.6 1.9 2.9 0.0 0.8 1.8 1.5 0.6 11.0 2.4 0.7 2.4 0.1 7.2 2.2 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "skeletal muscle: 7969.8;tongue: 2622.3" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 449.4;Skeletal myocytes: 598.7" "Group enriched" "Detected in many" 10 "cervical cancer: 12.7;head and neck cancer: 33.6;pancreatic cancer: 12.9;urothelial cancer: 39.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "CAPAN-2: 35.7;hTCEpi: 101.2" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Not detected" "Not detected" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Intermediate filaments" "CAB018697: AB_628400, HPA055938: AB_2682976" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (9.99e-3)" "unprognostic (1.01e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-3)" "unprognostic (5.62e-2)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" 3.0 1.8 0.3 1.1 0.3 6.1 7.9 0.3 0.6 1.0 0.4 1.2 0.3 0.8 0.3 66.9 0.9 5.6 1.7 0.3 0.4 0.7 1.6 7.8 1.6 0.4 0.4 0.7 8.8 0.0 0.9 3.0 0.4 14.0 0.2 0.0 216.1 3.2 7969.8 55.2 2.7 0.2 0.4 5.8 1.1 0.7 0.5 1.9 2.8 2622.3 1.0 27.4 3.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 35.7 1.0 0.2 0.0 0.0 1.7 0.0 1.3 0.0 0.0 0.0 0.1 0.0 2.1 0.2 0.0 0.1 8.1 101.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 3.1 0.0 0.1 1.2 2.4 0.0 1.0 0.0 1.0 0.0 0.7 0.0 0.0 12.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 13.8 5.8 53.3 0.1 12.5 0.1 3.8 0.0 0.0 8.0 4.8 0.0 0.0 39.7 0.4 17.6 86.4 0.0 2.5 0.3 0.3 0.3 0.6 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.6 1.2 3.2 4.4 0.0 9.1 25.1 2.6 1.8 15.4 0.0 0.5 23.7 5.6 21.5 3.0 0.0 0.0 33.8 15.7 0.1 0.0 1.4 0.0 1.4 0.2 2.0 0.0 0.0 0.0 0.6 449.4 2.4 1.1 0.1 10.8 0.4 0.4 0.3 39.6 0.0 0.0 0.0 2.0 18.8 10.7 0.0 0.3 25.9 0.0 0.0 16.0 0.0 1.0 0.0 0.0 1.4 0.0 0.0 4.2 0.1 0.0 0.2 13.2 0.0 0.0 598.7 2.4 0.0 0.6 2.7 6.5 87.2 1.9 4.3 0.0 0.9 TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 34.9;choroid plexus: 25.2;fallopian tube: 20.1" "Group enriched" "Detected in some" 4 "dendritic cells: 20.1;Endometrial ciliated cells: 65.4;Respiratory ciliated cells: 30.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;JURKAT: 1.2;NB-4: 1.3" "Low region specificity" "Detected in many" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "HPA037561: AB_10670384, HPA037562: AB_2675545, HPA075216: " "unprognostic (8.35e-5)" "unprognostic (2.85e-3)" "unprognostic (1.41e-1)" "unprognostic (7.01e-3)" "unprognostic (6.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-3)" "unprognostic (3.93e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-3)" "unprognostic (5.92e-2)" "unprognostic (3.94e-11)" "unprognostic (3.75e-2)" "unprognostic (4.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.81e-3)" 0.1 1.2 4.5 0.6 11.5 1.9 0.2 10.6 2.3 0.5 25.2 0.3 0.5 0.6 0.1 0.4 20.1 0.3 2.8 4.5 7.6 0.1 0.2 2.8 0.8 19.2 34.9 0.5 0.3 0.0 1.1 0.3 17.3 0.2 0.2 0.2 0.2 0.1 1.2 0.3 0.4 0.5 12.5 2.0 1.0 1.3 10.6 0.2 0.1 3.0 0.7 0.2 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.7 0.0 0.6 0.1 0.2 0.6 2.3 0.1 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.3 0.3 0.0 0.3 1.3 1.0 0.4 0.1 0.0 0.3 0.6 0.3 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.5 4.5 11.5 10.6 2.3 4.5 7.6 19.2 34.9 17.3 12.5 10.6 5.3 0.3 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 65.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.2 30.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.6 0.5 0.0 0.0 TOM1 ENSG00000100284 "Target of myb1 membrane trafficking protein" O60784 22 35299275-35347992 "Cancer-related genes, Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 213.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 170.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000818, HPA001749" Approved Approved "Plasma membrane,Centriolar satellite,Cytosol" NA NA 44000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane, Centriolar satellite" "HPA000818: AB_2666101, HPA001749: AB_1080323" "unprognostic (3.75e-1)" "unprognostic (8.07e-2)" "unprognostic (5.18e-2)" "prognostic favorable (2.20e-5)" "unprognostic (1.11e-2)" "unprognostic (7.55e-2)" "unprognostic (4.07e-3)" "unprognostic (2.24e-1)" "unprognostic (9.92e-2)" "unprognostic (2.32e-1)" "unprognostic (3.71e-1)" "unprognostic (8.16e-2)" "prognostic favorable (3.72e-5)" "unprognostic (1.22e-1)" "unprognostic (1.30e-1)" "unprognostic (7.54e-3)" "unprognostic (3.31e-2)" 34.7 47.8 20.8 17.0 19.4 60.8 32.1 19.9 25.8 43.6 23.6 22.7 29.1 26.6 12.7 76.5 26.8 24.9 43.2 19.8 26.6 32.7 49.0 37.1 15.3 30.2 24.5 21.5 20.2 48.5 37.4 27.7 32.9 23.2 9.8 5.9 60.6 11.7 213.8 74.9 28.4 10.8 19.6 23.9 20.8 25.9 24.8 13.1 26.5 68.6 12.7 19.5 45.0 22.1 15.8 15.3 8.8 14.3 58.3 34.9 42.3 15.5 43.8 28.4 31.1 21.5 14.3 6.2 28.0 45.4 18.3 7.3 8.6 15.6 9.9 18.7 21.3 5.3 17.1 43.8 58.6 10.8 23.6 49.8 19.2 39.6 13.3 18.5 19.8 11.6 10.3 15.3 14.1 13.8 8.2 27.5 7.0 18.9 8.6 14.9 12.3 13.2 10.9 11.3 14.9 12.1 34.1 34.8 34.5 7.3 18.0 16.7 22.0 34.0 29.4 27.3 7.7 18.0 12.4 16.7 45.7 10.5 11.4 18.6 100.9 44.5 19.3 60.7 15.6 13.6 29.5 18.4 48.0 11.0 22.6 15.7 129.1 15.1 66.2 25.9 48.2 63.3 20.8 19.4 19.9 25.8 19.8 26.6 30.2 24.5 32.9 19.6 24.8 22.1 10.1 22.4 36.9 8.8 12.7 12.7 10.3 29.5 7.4 11.1 19.1 11.0 23.2 15.7 33.0 12.9 12.5 64.6 13.8 41.6 27.4 40.9 29.9 32.0 17.8 14.2 16.2 9.7 9.3 38.9 57.1 22.6 15.3 48.0 22.8 10.4 16.1 34.0 60.8 11.8 15.2 18.1 50.8 33.5 35.2 21.4 11.5 45.2 19.6 7.5 34.0 19.5 9.2 6.6 13.2 34.2 21.5 12.8 5.7 11.9 55.3 34.9 24.2 8.2 6.6 16.6 15.4 23.5 5.6 17.3 21.9 170.2 18.2 13.4 15.2 10.7 TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 69.1;Theca cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA071229: AB_2732175" "unprognostic (1.67e-1)" "unprognostic (9.19e-3)" "unprognostic (1.47e-1)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (6.97e-2)" "unprognostic (2.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-3)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "prognostic favorable (7.51e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-1)" "unprognostic (2.82e-2)" 6.8 10.7 9.6 6.8 9.3 26.9 6.7 9.4 13.2 7.9 9.5 12.2 11.2 6.7 3.4 11.4 7.0 4.9 5.4 9.2 9.1 10.2 14.0 8.7 7.7 9.4 9.2 8.2 13.6 3.1 10.0 7.9 8.9 8.1 5.4 2.9 8.7 3.6 3.3 9.5 12.8 2.7 8.6 20.8 11.8 20.4 9.7 8.4 8.7 2.2 4.5 7.1 7.1 9.1 7.4 11.5 9.7 12.2 4.7 4.6 13.0 5.1 6.3 8.0 6.3 7.9 12.6 13.6 7.5 4.4 6.0 23.2 3.0 6.4 2.2 21.1 11.0 5.2 10.6 9.7 7.7 11.0 27.0 7.4 11.8 7.4 3.9 4.0 11.5 16.2 16.2 37.3 4.7 43.4 14.3 34.7 8.7 24.0 9.9 23.4 4.5 30.9 8.3 6.9 21.0 8.3 4.7 16.6 5.3 5.3 37.0 21.4 7.2 5.2 6.0 9.1 6.0 23.4 21.8 5.6 6.4 17.8 5.0 26.5 68.5 96.5 32.8 80.2 26.1 12.1 18.9 32.5 71.6 18.0 14.0 25.2 44.0 26.9 78.3 16.2 32.2 41.5 9.6 9.3 9.4 13.2 9.2 9.1 9.4 9.2 8.9 8.6 9.7 9.1 5.3 3.2 5.1 6.2 12.4 1.5 4.4 16.6 1.2 13.7 8.7 5.8 0.6 15.7 9.6 3.7 0.0 37.9 16.0 26.4 1.9 19.1 69.1 7.0 5.7 8.5 22.8 34.1 5.5 27.4 38.9 10.1 8.2 10.8 5.7 11.7 15.0 7.5 56.9 8.4 4.6 20.4 20.3 33.9 8.3 10.7 11.5 26.2 3.6 2.8 25.2 11.7 30.9 6.0 3.7 15.5 28.7 11.3 21.1 6.0 33.9 8.7 7.7 14.6 0.0 2.5 4.2 30.6 10.9 7.5 1.4 51.9 15.0 114.6 18.3 4.9 TP53BP2 "53BP2, ASPP2, PPP1R13A" ENSG00000143514 "Tumor protein p53 binding protein 2" Q13625 1 223779893-223845954 "Cancer-related genes, Predicted intracellular proteins" "Apoptosis, Cell cycle" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 152.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021603, HPA050429" Supported Enhanced "Cell Junctions,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 41: Macrophages - Immune response" "Cell Junctions, Cytosol" "HPA021603: AB_1844384, HPA050429: AB_2681124" "unprognostic (1.29e-1)" "unprognostic (5.11e-2)" "unprognostic (3.24e-1)" "unprognostic (1.38e-3)" "unprognostic (1.24e-1)" "unprognostic (1.03e-1)" "unprognostic (7.65e-2)" "unprognostic (1.93e-1)" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (7.37e-2)" "unprognostic (2.67e-1)" "unprognostic (7.99e-2)" "unprognostic (5.08e-2)" "unprognostic (1.24e-1)" "unprognostic (2.81e-2)" "unprognostic (1.83e-1)" 11.7 8.5 35.3 12.2 37.2 49.8 9.5 34.7 39.4 11.4 35.6 9.9 8.5 12.6 10.0 16.8 10.1 18.4 12.2 33.0 34.4 9.7 14.9 18.4 12.8 34.9 35.8 13.8 12.0 15.8 7.1 8.9 33.2 8.9 9.9 38.0 12.4 8.1 13.0 13.0 10.0 11.1 33.5 9.3 12.4 11.2 37.4 15.8 20.7 11.2 13.1 16.6 11.7 35.8 32.8 16.2 42.9 27.3 15.0 14.5 27.3 20.6 29.3 29.4 25.1 33.6 19.2 0.0 17.5 17.3 21.3 21.9 33.9 12.3 39.3 62.9 33.2 43.1 15.2 11.5 30.3 36.0 28.9 17.5 13.3 27.2 27.7 22.1 17.7 23.6 55.7 31.7 24.8 9.5 27.5 22.2 37.0 19.7 15.6 36.0 44.7 3.7 26.5 20.4 36.9 47.6 22.8 27.9 29.9 27.9 15.8 48.6 20.7 30.0 21.1 32.7 39.2 15.4 17.3 26.4 18.1 23.9 35.0 4.8 1.2 0.8 0.9 1.3 1.2 0.9 1.1 1.8 1.3 0.8 1.1 0.8 1.4 3.3 1.0 0.8 0.8 1.0 35.3 37.2 34.7 39.4 33.0 34.4 34.9 35.8 33.2 33.5 37.4 35.8 18.2 48.1 22.7 76.4 23.7 17.2 41.6 7.2 21.1 8.1 12.6 8.0 20.3 18.6 28.3 7.3 52.1 10.3 24.2 13.0 1.9 20.4 1.1 45.0 42.2 19.1 14.9 54.3 1.7 10.7 5.9 22.6 21.9 152.0 48.8 14.1 8.6 10.7 9.8 0.0 5.3 8.7 14.2 14.1 44.4 2.4 10.5 41.7 8.8 23.4 9.6 10.0 7.2 27.2 29.0 21.4 7.3 8.6 27.4 30.9 6.7 5.5 15.6 45.5 0.0 41.2 26.3 12.3 20.1 21.1 11.6 4.8 38.8 31.4 10.2 40.6 TPD52L1 "D53, hD53, TPD53" ENSG00000111907 "TPD52 like 1" Q16890 6 125119049-125264407 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 258.3;salivary gland: 298.3" "Cell type enhanced" "Detected in many" "Astrocytes: 390.1;Squamous epithelial cells: 272.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AN3-CA: 269.1;hTCEpi: 234.3;MCF7: 365.5;RPTEC TERT1: 271.4;SK-BR-3: 189.4;T-47d: 162.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027915, HPA027916" Enhanced Approved "Plasma membrane,Cell Junctions,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cell Junctions, Cytosol" "HPA027915: AB_10602074, HPA027916: AB_10601860" "unprognostic (1.44e-1)" "unprognostic (2.01e-2)" "unprognostic (2.76e-2)" "unprognostic (1.26e-1)" "unprognostic (1.39e-1)" "unprognostic (2.87e-2)" "unprognostic (1.38e-2)" "unprognostic (2.14e-1)" "unprognostic (7.85e-2)" "unprognostic (7.80e-2)" "unprognostic (9.42e-3)" "unprognostic (1.76e-1)" "prognostic favorable (3.26e-4)" "unprognostic (1.06e-1)" "unprognostic (6.83e-2)" "prognostic favorable (3.97e-4)" "prognostic unfavorable (5.34e-4)" 44.7 258.3 83.9 10.1 96.2 0.8 67.0 72.6 97.4 35.8 103.4 36.2 9.7 15.2 68.8 152.4 34.6 27.3 71.4 78.4 81.3 40.6 58.4 10.9 6.6 81.4 76.8 20.7 47.1 67.3 24.8 8.9 78.8 41.0 13.0 1.9 298.3 79.1 111.9 47.9 10.6 12.3 68.5 2.0 43.1 5.1 81.5 3.4 60.7 126.2 12.3 59.6 60.8 76.6 37.7 42.0 0.5 269.1 2.4 0.6 63.3 6.2 5.9 0.0 0.7 67.3 46.9 0.1 136.2 31.2 9.1 83.8 8.4 58.2 0.2 0.8 58.0 0.8 58.0 0.5 5.7 0.2 0.1 7.4 234.3 0.1 30.7 82.5 0.0 0.0 30.5 0.6 4.7 365.5 0.0 0.7 4.4 36.8 22.7 0.4 0.1 0.0 271.4 9.8 9.1 0.2 70.5 189.4 4.6 9.6 162.3 0.8 0.2 1.8 5.9 0.5 2.0 0.1 0.1 0.2 1.0 0.3 0.7 1.8 0.5 0.3 0.3 0.2 0.3 0.3 0.6 0.2 0.2 0.4 0.7 0.5 2.7 2.6 0.1 0.4 0.2 0.4 83.9 96.2 72.6 97.4 78.4 81.3 81.4 76.8 78.8 68.5 81.5 76.6 141.6 0.0 28.3 390.1 2.2 19.6 44.6 70.2 128.1 3.8 164.4 154.9 45.8 25.8 51.7 125.0 4.2 32.7 3.2 3.9 176.1 30.7 6.9 71.7 21.1 87.2 16.2 0.0 16.4 110.8 140.2 18.8 13.7 184.5 2.5 29.5 15.4 59.9 10.9 0.0 48.2 11.3 83.4 2.1 5.2 4.9 17.4 3.4 131.6 28.1 0.6 3.9 1.0 11.6 2.9 35.3 2.3 36.5 2.6 37.1 10.9 45.4 15.7 1.3 0.0 177.1 10.1 5.7 9.2 272.2 37.2 14.4 3.5 53.8 17.8 19.2 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 8.2;Spermatocytes: 15.6;Spermatogonia: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 1.5 1.0 1.6 1.8 2.5 6.8 1.9 0.7 1.8 2.0 0.4 2.3 1.5 1.7 1.4 2.9 1.8 1.0 0.9 1.6 0.9 0.8 0.8 0.9 4.6 0.6 0.6 2.1 1.0 0.8 1.2 1.6 0.7 1.4 2.9 2.3 1.2 0.9 2.0 4.2 2.0 2.1 0.6 1.9 1.2 7.9 1.3 5.3 1.4 1.2 4.4 1.3 1.9 0.9 10.4 12.4 17.4 17.6 1.6 2.4 14.4 12.4 5.8 25.3 24.0 15.2 11.6 25.5 8.5 7.1 17.7 13.4 18.5 14.0 18.8 14.7 12.2 19.2 16.3 13.6 0.7 15.8 15.4 1.6 2.0 20.4 10.7 3.0 6.7 22.3 14.0 17.8 11.4 15.1 26.5 20.1 14.0 12.3 20.3 14.4 11.7 14.8 4.6 14.2 8.4 14.4 13.6 11.3 8.8 12.4 10.2 22.4 5.2 16.1 19.0 22.5 24.4 13.0 33.7 27.3 8.1 21.2 14.6 0.0 0.6 0.3 0.9 0.3 0.9 2.9 0.5 2.1 0.6 1.5 0.7 1.1 0.1 1.2 1.3 0.7 0.3 0.6 1.6 2.5 0.7 1.8 1.6 0.9 0.6 0.6 0.7 0.6 1.3 0.9 0.6 3.2 0.6 1.0 1.8 1.1 0.6 1.5 2.2 2.8 1.2 1.4 2.6 0.0 0.3 3.7 0.0 4.2 1.2 1.8 0.0 2.0 4.3 0.6 0.9 0.8 0.0 3.8 1.4 1.0 8.2 2.0 1.5 0.9 0.0 5.7 1.1 0.7 3.5 0.0 0.9 2.0 0.0 0.8 0.4 4.8 2.5 0.7 1.8 1.0 1.8 1.7 0.0 0.5 0.6 1.1 0.3 1.2 4.3 0.8 0.9 0.3 0.5 3.3 0.0 1.4 1.7 15.6 9.1 2.3 0.3 1.0 1.2 1.2 4.6 0.2 TRAPPC13 "C5orf44, FLJ13611, MGC48585" ENSG00000113597 "Trafficking protein particle complex 13" A5PLN9 5 65625004-65666233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037777 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA037777: AB_10672464" "unprognostic (3.66e-2)" "unprognostic (3.27e-1)" "unprognostic (1.54e-2)" "unprognostic (7.22e-2)" "unprognostic (4.79e-2)" "unprognostic (1.16e-2)" "unprognostic (2.55e-2)" "unprognostic (2.49e-2)" "unprognostic (5.70e-2)" "unprognostic (5.75e-2)" "unprognostic (3.49e-2)" "unprognostic (1.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (2.89e-1)" "unprognostic (2.58e-2)" "unprognostic (2.53e-2)" "unprognostic (6.25e-2)" 10.0 11.5 7.8 8.9 8.4 8.0 12.8 9.1 9.9 10.6 7.0 10.8 9.3 10.8 9.1 12.4 8.9 9.3 16.8 8.3 9.4 20.0 14.7 10.5 10.8 8.7 8.8 7.6 7.3 22.7 8.8 10.4 8.8 18.7 13.3 16.6 9.1 10.9 13.4 5.8 9.1 12.9 9.1 9.9 10.0 10.6 8.7 16.6 17.3 16.8 10.8 12.1 7.0 10.4 20.7 13.6 21.0 38.2 15.8 20.2 20.7 23.8 21.2 29.1 31.2 11.8 28.7 21.3 25.5 19.5 31.0 18.8 24.0 25.0 33.9 14.6 17.8 13.4 15.3 11.1 21.7 16.6 19.3 14.5 19.2 22.7 28.8 17.5 25.8 30.0 16.2 19.1 26.3 21.9 27.3 6.4 9.5 11.9 7.4 23.7 26.9 24.0 20.8 23.2 25.4 19.2 29.3 17.4 22.2 11.6 25.7 20.8 17.8 10.2 14.0 22.6 24.4 12.6 26.3 34.0 21.3 28.9 19.8 17.6 8.3 3.6 8.4 9.3 11.0 5.8 8.1 7.0 9.0 4.7 7.9 7.9 3.1 8.9 13.4 6.7 9.3 9.1 7.8 8.4 9.1 9.9 8.3 9.4 8.7 8.8 8.8 9.1 8.7 10.4 10.4 19.2 10.5 27.1 7.4 5.7 6.8 17.3 6.2 13.3 8.5 5.5 7.1 12.8 13.1 7.3 10.4 12.1 13.0 7.6 15.6 12.9 24.6 7.9 7.6 11.9 15.5 12.0 54.7 10.8 9.6 9.1 11.2 7.6 3.8 9.8 8.2 11.2 12.4 13.5 44.2 8.9 26.4 13.9 7.7 10.2 7.5 9.6 7.2 28.1 11.1 14.8 11.3 46.3 66.5 10.3 6.3 13.2 8.9 11.8 11.0 25.2 13.4 16.2 6.6 8.7 8.3 16.4 8.6 9.1 6.8 15.2 12.0 10.2 8.7 11.9 TRAT1 "HSPC062, TCRIM, TRIM" ENSG00000163519 "T cell receptor associated transmembrane adaptor 1" Q6PIZ9 3 108822770-108855005 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "lymphoid tissue: 79.8" "Cell type enriched" "Detected in some" 10 "T-cells: 129.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 395.1" "Group enriched" "Detected in many" 155 "granulocytes: 395.1;T-cells: 313.1" "Group enriched" "Detected in some" 25 "JURKAT: 29.9;MOLT-4: 76.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA002356, CAB026130, HPA072760" Enhanced Enhanced "Plasma membrane,Mitotic spindle,Centriolar satellite" Yes NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Mitotic spindle, Centriolar satellite" "CAB026130: , HPA002356: AB_1080375, HPA072760: " "unprognostic (1.54e-4)" "unprognostic (1.41e-3)" "unprognostic (6.82e-2)" "unprognostic (4.95e-3)" "unprognostic (2.84e-2)" "unprognostic (2.19e-3)" "unprognostic (1.87e-3)" "unprognostic (2.02e-2)" "unprognostic (7.21e-3)" "unprognostic (8.96e-3)" "unprognostic (8.03e-2)" "unprognostic (4.32e-1)" "unprognostic (2.86e-5)" "unprognostic (3.12e-1)" "unprognostic (3.01e-2)" "unprognostic (2.90e-4)" "unprognostic (4.36e-2)" 1.1 0.6 0.0 11.0 0.0 2.7 0.8 0.0 0.0 0.4 0.0 1.3 1.4 0.4 0.4 1.0 0.3 2.5 0.4 0.1 0.0 0.3 1.3 2.1 23.9 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.8 1.5 0.0 0.6 0.1 0.1 0.6 3.0 0.5 0.0 8.5 2.4 0.4 0.0 79.8 0.4 0.4 12.4 2.9 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.9 0.0 2.1 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.6 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 395.1 0.6 0.2 57.0 0.2 116.4 1.0 229.5 119.6 0.3 0.4 313.1 77.7 3.5 2.2 0.7 0.8 111.1 139.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.2 0.0 3.3 8.4 0.1 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 1.8 0.0 0.0 8.9 0.1 0.0 0.0 2.3 0.1 0.1 1.1 0.0 2.7 0.1 0.0 0.0 1.7 7.7 0.1 2.5 0.0 1.8 0.6 0.2 0.0 0.2 0.0 0.0 1.0 12.2 2.2 0.0 1.8 3.6 0.0 3.2 0.0 3.1 0.0 0.2 0.0 0.0 0.0 5.1 0.2 0.0 0.5 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.0 8.0 0.1 129.3 0.6 0.0 0.2 TRDN TRISK ENSG00000186439 Triadin Q13061 6 123216339-123637093 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 421.6;skeletal muscle: 1944.1;tongue: 1018.2" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 1145.1;Muller glia cells: 765.7;Skeletal myocytes: 398.6" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.2;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.9" "Region enriched" "Detected in some" 10 "olfactory bulb: 11.0" "Region enriched" "Detected in some" 23 "olfactory bulb: 28.9" "HPA038226, HPA058226" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA038226: AB_10795574, HPA058226: AB_2683643" "unprognostic (1.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.20e-2)" "unprognostic (3.06e-3)" "unprognostic (2.40e-1)" "unprognostic (2.38e-1)" "unprognostic (2.42e-1)" "unprognostic (8.42e-2)" "unprognostic (8.71e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (2.55e-2)" "unprognostic (3.97e-2)" 16.3 2.6 4.2 0.0 3.7 0.0 2.0 4.0 5.8 0.7 3.1 0.4 0.0 1.7 10.4 18.5 12.5 0.2 421.6 3.0 12.5 0.4 0.1 0.4 0.1 6.7 7.0 1.3 0.1 0.0 15.3 0.2 7.9 17.0 0.3 83.5 13.1 0.9 1944.1 0.6 0.2 1.0 9.2 0.1 0.1 5.1 10.2 0.3 0.3 1018.2 0.1 0.0 0.6 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.7 4.0 5.8 3.0 12.5 6.7 7.0 7.9 9.2 10.2 6.3 0.3 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 7.9 0.0 0.3 1145.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 68.0 0.0 0.0 6.0 0.0 0.0 1.1 0.0 0.0 38.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.4 35.5 13.1 0.5 1.8 0.0 0.0 765.7 0.0 3.0 3.2 0.0 0.0 11.3 0.0 0.0 0.0 0.2 0.0 21.8 0.0 398.6 7.1 1.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TREML1 "dJ238O23.3, TLT1" ENSG00000161911 "Triggering receptor expressed on myeloid cells like 1" Q86YW5 6 41149342-41154337 "Plasma proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 8.7;brain: 4.5;lymphoid tissue: 7.3" "Group enriched" "Detected in some" 7 "Macrophages: 75.6;monocytes: 28.3" "Cancer enhanced" "Detected in some" "glioma: 1.6" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "basophil: 92.4" "Lineage enriched" "Detected in many" 49 "granulocytes: 92.4" "Cell line enriched" "Detected in single" 170 "HEL: 66.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA016700, HPA017860" Enhanced Uncertain "Nuclear speckles,Golgi apparatus,Plasma membrane,Cytosol" NA NA 43000000 "Cluster 34: Basophils - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Nuclear speckles, Cytosol" "Golgi apparatus, Plasma membrane" "HPA016700: AB_1858262, HPA017860: AB_1858261" "unprognostic (6.70e-2)" "unprognostic (3.50e-3)" "unprognostic (1.15e-3)" "unprognostic (1.62e-1)" "unprognostic (3.48e-2)" "unprognostic (4.53e-5)" "unprognostic (1.10e-2)" "unprognostic (2.55e-3)" "unprognostic (4.50e-1)" "unprognostic (2.12e-3)" "unprognostic (2.34e-2)" "unprognostic (7.04e-2)" "unprognostic (1.11e-4)" "unprognostic (1.36e-1)" "unprognostic (8.38e-2)" "unprognostic (7.51e-2)" "unprognostic (3.41e-2)" 0.9 1.0 1.7 2.7 2.1 8.7 0.5 2.2 4.5 0.3 1.3 0.3 0.0 0.1 0.4 0.1 0.4 0.9 0.3 1.9 2.5 0.2 0.3 2.1 5.4 3.3 2.4 0.1 0.4 0.2 0.4 0.5 2.8 0.2 0.9 0.2 0.4 0.3 0.1 0.3 0.4 0.2 2.5 7.3 0.2 0.1 3.6 4.1 0.3 0.5 4.8 0.4 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 66.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 92.4 1.7 2.8 0.2 1.8 0.4 0.2 0.1 0.0 0.7 0.3 0.5 0.0 10.7 0.0 0.3 0.9 0.0 110.6 1.7 2.1 2.2 4.5 1.9 2.5 3.3 2.4 2.8 2.5 3.6 3.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.8 0.0 0.0 0.0 0.9 0.1 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.9 0.0 3.9 0.0 0.0 0.0 0.0 1.6 2.7 0.0 0.0 75.6 0.0 6.5 28.3 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 6 "HEL: 1.1" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA065044: AB_2685411" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (5.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-4)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.9 0.0 0.0 8.1 0.0 0.4 0.7 0.0 0.4 0.0 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430358-125438403 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 365.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 242.7;Distal enterocytes: 281.6;Endometrial stromal cells: 240.1;Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 9.9;neutrophil: 4.7;non-classical monocyte: 3.5;T-reg: 2.8" "Group enriched" "Detected in many" 12 "granulocytes: 9.9;monocytes: 3.5;T-cells: 2.8" "Cell line enhanced" "Detected in many" "HEL: 193.9;U-266/70: 114.2;U-266/84: 123.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA063982: AB_2685165" "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 82.5 25.5 7.5 40.9 9.0 365.5 28.0 12.1 16.2 35.9 7.0 45.1 20.4 25.5 13.6 33.5 15.7 80.2 18.3 8.2 10.1 23.9 139.6 53.7 17.2 9.0 8.4 4.1 43.0 78.9 12.0 28.9 8.7 45.4 51.9 16.3 19.2 7.1 44.0 20.4 32.0 43.2 7.5 22.3 38.0 6.9 11.9 36.0 107.5 19.2 18.0 99.1 5.4 7.6 14.7 16.4 2.2 4.6 4.6 8.8 25.4 9.4 13.2 6.8 2.3 22.1 18.9 26.5 8.5 6.9 40.6 11.0 7.0 9.1 5.8 11.8 34.3 193.9 7.3 43.6 11.6 98.3 17.0 8.5 13.5 27.8 62.8 33.0 20.0 0.3 17.5 81.6 0.9 15.8 9.2 15.3 15.8 35.1 31.6 18.5 3.3 29.2 54.6 55.1 13.7 5.0 22.9 24.6 93.1 14.0 6.4 4.6 10.4 7.3 9.5 7.3 11.7 114.2 123.2 36.6 13.1 0.7 17.7 0.0 0.7 9.9 0.0 1.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 4.7 0.0 3.5 0.3 2.8 0.1 7.5 9.0 12.1 16.2 8.2 10.1 9.0 8.4 8.7 7.5 11.9 7.6 69.6 134.6 168.5 13.7 19.8 100.1 242.7 68.6 77.4 25.5 100.8 71.9 16.6 31.5 67.9 16.5 0.0 12.3 2.8 281.6 11.7 45.3 0.4 96.6 240.1 62.0 112.0 5.3 2.1 24.7 19.1 54.6 58.6 222.5 29.9 0.5 8.2 131.7 35.3 21.9 0.7 129.6 32.6 72.0 59.7 1.7 0.3 85.9 56.9 4.7 27.5 20.1 0.0 4.5 0.2 45.5 130.9 0.4 283.6 139.0 117.4 24.9 39.7 3.8 0.0 36.6 45.1 0.3 2.2 88.2 64.2 30.6 14.8 1.5 106.9 128.7 TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 153.4;Squamous epithelial cells: 95.5;Urothelial cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Cell line enhanced" "Detected in all" "A549: 283.8;HaCaT: 229.0;HeLa: 203.8;OE19: 364.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" 18.3 32.7 14.1 7.8 16.2 17.4 13.4 17.7 21.5 44.9 10.3 14.1 22.8 6.1 4.9 145.9 8.8 16.3 23.1 13.5 15.8 8.5 5.9 14.5 9.7 16.9 16.0 7.3 6.0 3.6 4.4 34.5 17.2 10.2 11.2 3.6 38.0 11.7 28.1 44.9 12.5 9.0 15.8 6.0 31.7 12.7 17.2 10.1 18.7 27.2 37.3 35.7 70.2 22.1 91.5 283.8 8.6 19.4 40.4 46.1 9.6 14.8 51.9 17.9 25.0 17.2 115.6 9.8 54.7 64.7 106.9 229.0 25.6 65.7 12.0 120.0 16.4 4.5 203.8 9.5 67.1 5.4 9.6 25.7 40.9 39.3 22.3 49.6 38.8 11.4 5.7 45.8 49.2 32.2 20.2 11.7 13.1 364.2 17.0 8.7 71.8 6.9 92.4 116.0 6.4 17.7 64.7 72.2 22.1 49.7 10.9 12.6 61.0 22.5 26.3 10.9 51.3 11.1 12.9 1.0 34.6 12.6 58.3 0.4 3.8 1.0 1.2 1.1 0.8 0.5 4.9 1.5 2.6 0.6 1.3 2.6 0.6 0.9 0.5 0.4 45.1 2.3 14.1 16.2 17.7 21.5 13.5 15.8 16.9 16.0 17.2 15.8 17.2 22.1 34.9 38.5 2.6 14.0 5.3 30.8 59.0 55.6 10.2 7.2 11.8 5.7 12.5 10.0 73.5 11.0 18.8 13.6 2.8 9.9 0.0 49.1 1.1 16.5 9.9 28.7 4.2 9.0 9.6 17.3 8.4 9.6 34.7 25.7 4.5 12.4 3.6 3.2 4.0 3.3 14.0 21.7 28.5 2.9 8.6 3.9 7.2 2.9 7.2 11.2 13.0 6.6 4.1 18.6 19.2 153.4 26.9 4.5 3.7 29.5 4.3 6.2 33.5 8.4 6.6 5.8 14.0 10.3 12.1 95.5 77.6 4.7 5.9 60.9 18.4 111.9 TRIM38 "RNF15, RORET" ENSG00000112343 "Tripartite motif containing 38" O00635 6 25962802-25991231 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA031685 Approved Approved "Plasma membrane,Cell Junctions,Centrosome" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" Centrosome "Plasma membrane, Cell Junctions" "HPA031685: AB_10603218" "unprognostic (6.62e-2)" "unprognostic (1.65e-3)" "unprognostic (3.34e-1)" "unprognostic (2.72e-2)" "unprognostic (1.25e-1)" "unprognostic (6.51e-2)" "unprognostic (7.79e-2)" "unprognostic (3.27e-2)" "unprognostic (2.78e-2)" "prognostic favorable (8.95e-5)" "unprognostic (2.81e-2)" "unprognostic (6.28e-2)" "unprognostic (2.73e-1)" "unprognostic (3.36e-1)" "unprognostic (4.49e-2)" "prognostic favorable (8.20e-5)" "prognostic favorable (4.94e-9)" 7.1 6.0 1.8 10.8 1.8 13.0 6.1 1.6 2.4 7.3 3.4 5.8 6.6 7.3 9.6 7.8 7.4 6.6 3.7 1.7 1.9 9.9 5.6 9.3 13.6 3.0 2.1 4.6 3.2 2.9 2.0 6.3 2.7 7.0 7.3 0.4 6.1 6.2 7.6 5.2 8.9 6.1 2.4 14.3 5.8 2.1 2.7 7.7 5.5 3.0 14.6 7.0 7.0 2.7 4.8 2.6 0.4 5.6 13.0 17.3 4.6 5.9 11.7 11.2 18.5 2.0 5.0 10.5 9.4 7.3 10.8 7.3 3.6 5.8 6.6 10.7 2.3 4.8 4.6 2.0 17.2 5.7 9.4 17.4 4.2 6.9 2.5 9.2 9.8 5.0 3.2 5.7 13.5 2.3 5.5 6.4 1.8 0.0 3.5 8.3 5.4 11.2 13.3 9.3 0.1 0.1 4.4 9.1 16.2 0.6 1.3 7.3 10.1 2.0 3.4 3.5 4.0 6.5 5.1 11.7 5.4 6.9 12.6 12.1 10.2 4.7 6.9 12.5 6.6 13.1 5.8 6.2 9.8 15.1 5.4 6.0 11.4 6.5 11.7 9.0 7.9 7.1 1.8 1.8 1.6 2.4 1.7 1.9 3.0 2.1 2.7 2.4 2.7 2.7 37.6 25.6 47.1 0.3 120.2 14.9 56.9 16.1 24.5 0.6 20.1 12.8 6.0 18.6 32.4 46.0 0.0 23.5 88.5 48.3 17.6 28.5 1.1 48.4 28.1 39.9 18.1 10.3 0.1 14.9 23.5 25.5 24.5 69.4 35.5 52.4 35.0 17.5 32.6 0.0 0.1 33.3 16.2 94.0 32.7 2.8 19.9 81.3 10.6 34.7 113.2 0.2 107.1 0.0 0.2 20.4 47.4 18.8 34.3 39.7 48.3 69.5 22.7 1.1 6.6 23.1 28.2 0.3 0.5 42.7 9.2 21.2 53.1 23.0 25.6 94.7 TRIM4 RNF87 ENSG00000146833 "Tripartite motif containing 4" Q9C037 7 99876958-99919531 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019356, HPA029461" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA019356: AB_1856376, HPA029461: AB_10600834" "unprognostic (1.88e-1)" "unprognostic (2.97e-2)" "unprognostic (3.37e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-2)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (5.42e-2)" "unprognostic (3.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.48e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.36e-6)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (5.65e-2)" 18.7 21.5 11.0 17.1 11.5 9.3 26.8 15.5 12.6 18.9 15.4 17.3 17.5 23.7 19.8 15.3 22.9 15.2 10.0 10.5 11.9 20.6 22.9 18.5 22.4 11.2 11.9 41.3 23.8 25.5 16.2 19.9 10.9 23.0 19.2 21.5 19.0 20.2 7.5 21.8 18.6 19.9 10.7 21.5 20.1 16.0 12.0 20.9 24.5 11.8 23.8 17.3 17.3 13.3 20.8 26.2 14.4 12.0 37.0 34.6 6.3 34.6 41.3 28.0 32.4 13.1 20.1 30.3 0.1 28.8 24.2 24.3 19.0 21.2 28.4 31.2 1.4 25.3 13.1 20.8 52.4 35.9 29.4 36.9 44.3 21.6 54.7 37.8 24.6 14.9 37.1 45.3 23.9 26.4 26.8 32.2 10.9 31.0 21.0 15.0 20.6 34.6 31.6 26.4 16.8 11.9 26.4 39.4 42.3 20.7 18.2 20.2 30.6 30.7 27.6 59.5 33.6 37.7 44.4 24.0 20.1 39.7 41.7 38.2 28.4 23.6 28.5 28.6 32.8 26.2 29.4 32.6 24.9 25.3 40.7 30.4 11.7 22.3 26.1 18.5 32.8 28.0 11.0 11.5 15.5 12.6 10.5 11.9 11.2 11.9 10.9 10.7 12.0 13.3 17.8 25.6 20.1 19.2 32.3 25.1 24.8 17.7 25.0 21.6 21.8 18.0 6.1 18.6 14.2 22.0 18.8 16.4 28.1 10.1 9.8 15.9 7.4 12.5 25.4 18.8 9.0 16.8 18.3 12.8 6.7 20.1 19.4 11.4 27.3 19.0 22.5 20.4 14.3 6.7 20.7 10.4 16.2 21.4 14.8 13.1 31.1 21.2 23.2 12.2 27.0 35.9 32.0 23.1 22.5 14.9 10.4 27.4 20.1 26.6 17.8 19.0 16.5 22.1 0.0 21.8 20.4 22.4 9.4 18.0 23.0 16.3 29.8 52.5 13.5 23.6 TRIM44 "DIPB, MC7" ENSG00000166326 "Tripartite motif containing 44" Q96DX7 11 35662775-35818007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049053, HPA057633" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Plasma membrane" "HPA049053: AB_2680613, HPA057633: AB_2683484" "unprognostic (2.73e-1)" "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (5.53e-2)" "unprognostic (3.91e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (9.06e-2)" "unprognostic (5.29e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (1.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-1)" 12.6 10.7 16.9 12.3 16.4 6.0 11.1 18.5 21.9 10.9 8.3 13.5 10.6 10.9 10.2 9.1 11.1 11.6 11.6 16.6 17.0 18.0 14.4 11.9 12.8 16.0 16.7 10.3 15.5 11.1 7.9 13.3 16.1 10.4 11.1 27.0 9.4 11.4 11.5 8.3 12.0 12.2 17.8 14.1 11.3 6.7 17.3 12.1 14.9 9.8 13.2 11.1 8.6 19.0 20.1 16.9 26.4 12.3 19.6 29.6 0.1 18.5 21.9 22.7 20.6 19.7 13.3 26.7 17.1 24.3 25.7 15.4 9.1 21.1 25.4 17.6 17.4 28.7 23.0 11.4 26.0 22.7 23.7 22.4 23.2 13.3 36.0 25.1 24.3 9.2 45.4 9.3 24.1 12.1 24.1 11.1 14.9 4.2 14.5 16.6 68.4 14.5 21.0 26.9 18.1 15.5 27.7 19.6 21.0 14.3 29.5 19.0 27.4 28.9 23.8 16.6 21.2 15.7 15.0 0.1 23.9 23.7 22.2 0.2 0.9 0.3 0.9 1.2 0.8 1.1 0.9 0.9 0.8 1.5 1.1 1.2 0.0 1.2 1.5 1.8 0.3 0.5 16.9 16.4 18.5 21.9 16.6 17.0 16.0 16.7 16.1 17.8 17.3 19.0 67.5 60.9 72.6 78.4 68.5 26.8 57.9 19.8 74.0 221.5 45.3 38.2 58.9 55.8 45.6 25.8 204.3 55.4 72.1 70.3 33.2 62.8 18.8 78.0 74.0 62.4 51.4 39.3 151.7 71.1 25.9 49.4 74.9 54.4 58.9 107.1 49.2 53.3 42.7 84.1 134.5 57.6 16.2 65.7 37.8 13.4 36.1 70.3 19.6 84.3 76.9 72.2 72.1 121.7 171.0 53.3 50.4 37.2 59.6 90.3 50.9 75.6 48.4 173.4 98.6 71.9 52.1 88.2 81.5 46.1 26.7 52.1 47.0 58.5 54.5 59.9 TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 213.2;skeletal muscle: 580.7;tongue: 177.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 81.7;Ductal cells: 35.5;Exocrine glandular cells: 42.5;Pancreatic endocrine cells: 46.5;Skeletal myocytes: 17.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.1" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Group enriched" "Detected in some" 8 "HAP1: 7.3;NTERA-2: 15.6" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" 0.4 9.3 1.5 0.0 0.9 0.0 0.3 0.9 5.1 0.9 0.1 0.3 4.3 0.8 24.5 5.0 0.8 0.2 213.2 2.3 0.0 1.7 0.1 0.2 0.2 0.6 0.3 0.5 0.5 0.0 0.1 0.0 0.3 3.4 0.0 0.0 9.5 0.1 580.7 0.9 2.1 0.0 0.3 0.9 0.1 22.3 0.1 0.1 0.5 177.3 0.0 0.1 0.5 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.4 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 15.6 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 1.5 0.9 0.9 5.1 2.3 0.0 0.6 0.3 0.3 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.3 0.0 0.0 0.5 0.4 81.7 10.0 0.1 3.7 0.0 0.0 0.3 2.3 0.0 35.5 1.5 0.1 0.0 0.8 0.0 2.7 11.3 42.5 0.0 2.2 0.0 0.2 4.5 0.0 0.4 0.0 0.1 0.0 0.8 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.3 46.5 1.9 0.7 0.0 0.2 2.4 3.1 0.2 0.0 0.0 17.9 16.8 6.8 2.4 0.0 0.0 0.0 0.3 0.2 6.4 0.3 TRIM71 "LIN-41, LIN41" ENSG00000206557 "Tripartite motif containing 71" Q2Q1W2 3 32817997-32897824 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "RNA-mediated gene silencing, Ubl conjugation pathway" "Developmental protein, RNA-binding, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 4.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 9.6;Extravillous trophoblasts: 15.6;Inhibitory neurons: 4.5;Oligodendrocyte precursor cells: 4.5;Spermatogonia: 13.7" "Cancer enriched" "Detected in some" 28 "testis cancer: 28.6" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 31.4;BEWO: 94.5;Hep G2: 63.8;NTERA-2: 84.3;SuSa: 76.3" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038141, HPA038142" Uncertain Approved "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 5: NTERA-2 - Transcription" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Actin filaments, Focal adhesion sites" "HPA038141: AB_2675857, HPA038142: AB_10697240" "unprognostic (2.93e-2)" "unprognostic (4.29e-3)" "unprognostic (1.70e-1)" "unprognostic (1.02e-2)" "unprognostic (2.58e-2)" "unprognostic (3.27e-2)" "unprognostic (2.09e-2)" "unprognostic (1.25e-1)" "unprognostic (3.16e-2)" "unprognostic (3.04e-1)" "unprognostic (1.11e-2)" "unprognostic (3.11e-1)" "unprognostic (4.36e-6)" "unprognostic (3.92e-2)" "unprognostic (9.27e-2)" "unprognostic (8.17e-2)" "unprognostic (4.65e-2)" 0.0 0.0 1.0 0.0 1.0 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 0.9 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 31.4 0.0 0.0 0.0 94.5 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 1.6 0.0 63.8 0.0 1.8 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.4 0.0 0.0 0.6 6.9 84.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 76.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.0 0.0 0.8 0.9 0.8 0.1 0.1 0.1 0.0 0.8 0.2 0.0 9.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 2.7 0.0 1.8 0.0 0.0 3.9 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.2 0.0 0.0 3.1 0.0 15.6 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 4.5 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 1.0 0.1 0.0 0.0 4.5 0.1 0.0 0.0 0.4 0.0 0.0 0.0 3.6 0.7 0.5 0.0 0.0 0.1 0.3 13.7 0.0 0.0 4.0 0.1 0.0 0.0 0.0 TRIML2 "FLJ25801, SPRYD6" ENSG00000179046 "Tripartite motif family like 2" Q8N7C3 4 188091273-188109603 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 4.1;testis: 2.6" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 16.5;Early spermatids: 17.3;Extravillous trophoblasts: 6.7;Late spermatids: 5.2;Spermatocytes: 6.4;Spermatogonia: 6.4;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in some" 33 "testis cancer: 24.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA043838 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA043838: AB_10963835" "unprognostic (3.32e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (9.82e-2)" "unprognostic (1.21e-5)" "unprognostic (3.06e-2)" "unprognostic (1.65e-3)" "unprognostic (2.65e-1)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 33.8 0.0 0.0 0.0 0.1 18.3 0.2 1.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 7.5 0.9 6.4 0.1 0.0 2.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 145.3 0.0 0.0 0.2 0.1 7.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.1 0.0 0.0 1.6 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.5 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.4 6.4 0.0 0.0 8.9 0.1 0.0 0.0 0.3 TRIP6 "MGC10556, MGC10558, MGC29959, MGC3837, MGC4423, OIP1, ZRP-1" ENSG00000087077 "Thyroid hormone receptor interactor 6" Q15654 7 100867387-100873454 "Predicted intracellular proteins" "Cell adhesion, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB046454, CAB046460, HPA052813" Approved Supported "Plasma membrane,Focal adhesion sites,Cytosol" NA NA 21000 "Cluster 26: Non-specific - Mitochondria" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Focal adhesion sites, Cytosol" "CAB046454: AB_10604048, CAB046460: AB_2303907, HPA052813: AB_2681961" "unprognostic (7.94e-3)" "unprognostic (1.06e-1)" "unprognostic (3.22e-3)" "unprognostic (2.84e-3)" "unprognostic (3.52e-2)" "unprognostic (2.92e-2)" "unprognostic (3.18e-2)" "unprognostic (4.61e-3)" "unprognostic (8.48e-2)" "unprognostic (4.18e-2)" "unprognostic (5.08e-2)" "unprognostic (1.42e-1)" "unprognostic (1.25e-2)" "unprognostic (5.07e-2)" "unprognostic (9.71e-2)" "unprognostic (1.92e-1)" "unprognostic (1.25e-1)" 42.2 43.0 34.3 15.7 39.5 15.7 42.6 36.2 41.6 59.4 40.4 45.2 9.7 74.6 16.2 63.7 49.5 37.0 39.1 32.6 36.2 55.8 41.1 33.8 14.6 40.6 36.9 50.6 39.8 46.4 16.8 27.4 35.9 42.9 8.4 5.4 46.8 56.7 10.2 55.1 21.5 27.5 36.9 20.0 27.6 18.4 38.4 16.6 50.5 5.8 12.1 47.2 52.5 37.0 128.1 63.4 26.8 126.1 37.8 44.9 131.2 82.3 79.8 101.2 94.8 55.8 143.9 5.5 81.3 87.7 128.3 94.2 38.0 149.2 27.3 19.1 58.5 0.5 117.9 0.8 99.3 66.5 7.1 81.1 94.0 67.8 108.2 64.2 52.8 19.1 83.3 1.0 90.5 286.9 1.3 99.5 92.4 52.3 50.4 47.9 27.0 12.7 65.5 42.8 9.7 1.7 67.5 192.3 78.1 43.8 20.3 77.5 86.5 149.5 145.8 167.5 186.7 1.0 2.1 0.8 92.9 7.8 230.5 0.0 1.2 0.2 0.1 2.1 0.4 2.5 0.9 0.7 1.9 2.4 1.1 0.6 0.0 0.0 3.8 5.2 0.9 0.4 34.3 39.5 36.2 41.6 32.6 36.2 40.6 36.9 35.9 36.9 38.4 37.0 24.5 48.1 38.8 14.4 8.0 131.9 151.5 144.1 78.0 0.9 48.3 55.8 13.9 38.6 87.0 60.7 0.0 113.0 12.0 9.5 80.3 106.9 1.1 22.7 46.1 26.3 4.9 6.7 0.3 84.3 90.4 54.6 40.8 44.8 8.2 55.3 23.9 28.8 44.0 1.7 0.4 12.8 34.6 8.0 59.3 2.8 65.9 17.5 37.4 5.6 20.3 94.8 0.0 4.0 6.5 95.0 13.1 72.6 16.0 72.9 3.6 130.0 34.3 4.6 72.3 50.9 104.0 4.7 4.5 68.2 98.3 132.8 7.1 58.3 18.8 155.6 TRMT1 "FLJ20244, TRM1" ENSG00000104907 "TRNA methyltransferase 1" Q9NXH9 19 13104902-13117567 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, RNA-binding, Transferase, tRNA-binding" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 80.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041130, HPA041380" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 72: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" Nucleoplasm "HPA041130: AB_10803995, HPA041380: AB_10793873" "unprognostic (2.10e-2)" "unprognostic (2.40e-3)" "unprognostic (2.23e-2)" "unprognostic (1.01e-1)" "unprognostic (1.12e-2)" "unprognostic (5.54e-2)" "unprognostic (1.08e-3)" "unprognostic (2.19e-2)" "unprognostic (1.59e-1)" "unprognostic (7.62e-2)" "unprognostic (1.91e-2)" "unprognostic (8.74e-3)" "prognostic unfavorable (9.87e-7)" "unprognostic (1.19e-3)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "unprognostic (2.49e-2)" 22.0 19.8 16.5 16.2 15.3 21.1 21.0 14.7 22.1 24.3 14.8 20.0 11.8 22.9 6.3 22.3 23.6 8.9 17.3 15.5 14.7 18.0 22.1 17.3 23.2 16.0 14.8 28.7 25.4 10.0 17.2 11.3 16.8 23.0 10.9 6.5 17.0 11.4 28.8 23.4 21.7 12.5 14.2 30.6 18.9 16.8 16.2 11.6 19.2 10.5 15.9 22.3 22.2 17.6 38.6 25.3 26.9 46.0 26.7 34.1 38.7 42.1 20.9 45.3 39.1 27.4 30.8 47.7 53.6 22.9 23.7 34.8 45.2 37.3 20.9 31.3 62.8 38.0 68.7 46.5 48.7 77.2 43.1 48.4 48.4 47.3 44.1 28.9 33.8 35.2 83.7 14.9 28.6 42.6 31.7 83.3 64.0 24.2 57.5 52.5 34.6 65.8 28.3 38.2 63.5 28.9 26.2 53.7 44.8 19.4 21.0 42.8 38.2 65.1 25.5 39.8 75.1 25.6 53.4 44.1 30.3 80.7 34.7 1.8 18.9 0.6 8.9 15.0 8.6 12.4 9.6 8.6 18.2 12.9 11.1 8.5 3.7 5.6 9.9 10.6 6.9 10.7 16.5 15.3 14.7 22.1 15.5 14.7 16.0 14.8 16.8 14.2 16.2 17.6 15.5 12.8 13.1 8.5 47.5 24.0 27.0 16.8 22.8 8.9 16.6 20.2 8.3 11.5 9.6 12.9 2.1 21.7 19.6 16.6 5.9 17.3 22.4 7.9 11.7 17.6 7.2 13.0 12.0 14.9 22.6 14.3 17.9 9.8 29.8 19.7 6.1 10.8 47.7 8.4 9.1 14.1 4.1 80.0 51.0 47.9 14.0 57.4 17.8 10.3 64.8 6.1 12.3 2.5 7.5 12.8 6.8 12.8 24.2 29.0 7.8 14.2 9.2 12.6 13.1 17.5 16.1 21.1 20.0 20.7 20.6 15.5 24.4 14.6 22.5 20.3 TRMT10B "bA3J10.9, FLJ31455, RG9MTD3" ENSG00000165275 "TRNA methyltransferase 10B" Q6PF06 9 37753803-37778972 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021800 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA021800: AB_1856214" "unprognostic (1.00e-2)" "unprognostic (1.78e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (7.78e-2)" "prognostic favorable (3.91e-4)" "unprognostic (5.49e-3)" "unprognostic (1.71e-2)" "prognostic favorable (5.34e-4)" "unprognostic (1.40e-1)" "unprognostic (6.62e-2)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 5.6 6.9 7.3 5.7 8.1 6.0 6.2 10.7 8.0 8.3 5.8 8.3 4.4 7.1 4.4 5.5 7.6 4.1 4.9 6.8 7.3 6.9 6.4 4.9 7.4 7.9 7.6 9.5 7.9 3.9 6.7 3.8 7.1 8.3 3.5 7.3 6.1 4.2 4.4 10.7 7.1 4.0 6.6 8.1 6.7 3.4 7.6 4.0 7.6 2.1 4.2 7.6 7.1 9.8 4.7 5.6 7.0 6.2 4.2 3.3 3.1 4.4 3.3 4.5 3.9 3.3 4.1 8.7 3.3 3.4 2.7 5.3 3.3 5.5 4.1 3.7 5.6 7.8 14.8 3.5 7.6 8.0 5.2 3.8 5.5 4.3 7.4 5.3 4.7 10.4 6.2 3.6 3.4 3.3 8.1 6.2 6.2 5.0 6.7 8.1 2.4 4.6 4.3 4.2 9.4 9.0 3.7 4.7 4.1 4.4 5.0 5.7 4.8 3.6 5.1 5.9 4.0 4.2 6.1 6.9 2.1 6.1 7.3 3.4 2.7 1.5 3.1 2.4 3.8 3.3 2.8 3.1 1.2 4.3 3.3 3.0 2.8 2.4 1.7 2.3 1.9 1.5 7.3 8.1 10.7 8.0 6.8 7.3 7.9 7.6 7.1 6.6 7.6 9.8 13.2 3.2 8.9 30.3 20.3 7.4 11.4 8.9 15.9 16.2 13.5 16.5 7.4 14.3 8.4 3.7 6.2 16.1 11.0 7.9 11.7 11.3 2.1 7.1 14.1 12.8 13.8 13.7 25.4 12.5 8.6 14.0 13.7 9.1 14.5 17.3 13.6 8.1 8.2 16.8 27.5 14.0 8.2 10.4 9.5 0.9 14.6 12.2 10.6 19.7 15.5 15.9 25.7 37.2 45.7 10.0 6.7 23.7 9.1 14.2 11.4 9.0 7.8 13.5 26.3 13.0 11.1 4.2 5.3 9.7 7.5 12.2 16.4 12.3 10.9 9.4 TRMT13 "CCDC76, FLJ10287, FLJ11219" ENSG00000122435 "TRNA methyltransferase 13 homolog" Q9NUP7 1 100133150-100150498 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 97.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028494 Approved Approved "Nucleoplasm,Nuclear bodies,Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "Nuclear bodies, Cytosol" "HPA028494: AB_10601254" "unprognostic (1.12e-1)" "unprognostic (3.33e-1)" "unprognostic (5.76e-2)" "unprognostic (2.37e-1)" "unprognostic (9.17e-3)" "unprognostic (4.97e-2)" "prognostic unfavorable (5.81e-5)" "unprognostic (1.16e-3)" "unprognostic (3.28e-2)" "unprognostic (8.08e-2)" "unprognostic (3.22e-1)" "unprognostic (1.02e-3)" "prognostic unfavorable (6.89e-6)" "unprognostic (3.12e-2)" "unprognostic (7.71e-2)" "unprognostic (1.99e-2)" "unprognostic (1.70e-3)" 8.8 8.7 6.9 12.2 9.8 5.2 14.5 9.6 9.6 11.2 6.7 9.3 11.2 13.9 11.8 8.5 9.2 7.2 8.0 6.5 9.7 8.8 8.7 7.8 18.2 8.5 9.0 13.5 11.5 12.9 6.8 10.7 8.7 10.4 11.3 21.7 9.1 8.1 13.1 14.7 10.7 10.1 7.0 14.1 10.0 9.4 8.5 11.3 12.0 6.2 14.6 9.5 10.3 14.9 17.5 10.0 16.5 11.5 8.7 16.9 18.0 18.0 7.1 13.4 11.1 11.9 7.0 28.7 21.8 14.4 8.9 15.4 30.6 14.0 23.1 29.0 24.2 17.2 23.1 11.6 15.7 30.0 15.4 11.9 15.5 25.5 33.3 8.4 12.4 21.0 36.6 17.9 13.6 6.7 24.6 15.6 23.0 16.7 19.9 26.0 25.0 15.7 11.1 13.6 10.7 17.9 16.6 15.8 21.6 16.1 9.3 26.1 13.0 17.8 11.9 15.1 24.3 22.8 20.0 34.0 20.1 23.5 7.0 0.2 5.8 3.1 10.5 6.1 13.0 19.9 11.3 10.6 7.0 18.7 16.8 14.0 2.5 7.9 5.1 12.8 8.6 5.6 6.9 9.8 9.6 9.6 6.5 9.7 8.5 9.0 8.7 7.0 8.5 14.9 13.1 25.6 17.0 34.0 29.0 9.7 14.2 14.2 19.9 38.9 10.7 7.9 11.1 12.8 22.2 14.7 29.2 14.2 18.9 8.0 13.7 10.5 20.9 14.3 21.0 15.7 20.4 11.3 23.1 6.1 10.2 13.7 11.7 8.0 21.5 18.7 17.9 11.4 7.6 28.6 32.1 9.9 18.3 10.1 7.0 6.0 24.8 10.3 10.6 25.3 14.7 16.6 41.2 33.7 97.4 8.5 9.6 18.4 9.0 12.6 13.0 10.7 20.4 44.7 19.7 16.0 13.4 47.6 21.9 12.2 11.9 7.3 21.5 15.8 13.6 10.0 TRMT6 "CGI-09, GCD10, Gcd10p, MGC5029" ENSG00000089195 "TRNA methyltransferase 6" Q9UJA5 20 5937228-5950558 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatogonia: 103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047032, HPA050408" Approved Enhanced "Nucleoplasm,Cell Junctions" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Nucleoplasm "Cell Junctions" "HPA047032: AB_2679911, HPA050408: AB_2681117" "unprognostic (1.78e-1)" "unprognostic (4.51e-2)" "unprognostic (1.65e-1)" "unprognostic (4.26e-2)" "unprognostic (2.11e-1)" "unprognostic (6.81e-2)" "prognostic unfavorable (4.70e-12)" "unprognostic (5.37e-2)" "unprognostic (3.53e-2)" "unprognostic (1.14e-1)" "unprognostic (6.27e-2)" "unprognostic (1.22e-1)" "unprognostic (7.65e-3)" "unprognostic (2.52e-2)" "unprognostic (1.76e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" 7.4 9.7 5.1 7.3 5.3 13.8 5.9 5.9 6.3 5.9 4.5 5.8 3.4 6.6 6.0 9.1 5.7 3.5 7.7 5.4 5.2 8.0 5.5 4.9 9.3 5.8 5.1 5.6 7.3 6.8 8.4 5.1 5.8 5.2 5.5 3.7 6.1 9.9 20.2 7.8 5.9 5.6 4.9 6.6 5.8 11.5 4.8 8.8 5.9 7.3 9.0 11.0 6.4 5.1 55.5 27.8 17.1 25.9 10.4 11.8 21.4 24.7 12.5 24.5 20.6 36.5 22.2 62.1 13.1 15.1 33.8 39.9 36.3 41.8 40.3 13.3 25.5 50.6 12.0 32.2 19.8 47.8 13.3 13.6 21.8 44.4 33.4 8.6 10.0 25.6 32.3 18.0 28.8 14.4 50.6 26.2 39.5 36.9 33.9 33.4 33.6 36.1 18.3 31.3 33.9 51.1 29.2 39.3 45.0 16.2 20.2 24.4 8.8 28.5 27.1 26.8 52.1 31.6 64.1 74.6 13.3 37.9 29.3 2.1 7.8 6.3 9.1 9.1 10.9 8.6 9.9 11.5 18.0 8.1 10.1 11.1 0.7 15.6 8.3 7.5 12.5 7.2 5.1 5.3 5.9 6.3 5.4 5.2 5.8 5.1 5.8 4.9 4.8 5.1 11.7 6.4 20.3 2.0 20.0 21.4 26.1 35.8 25.0 19.8 12.6 14.9 25.9 15.7 31.3 29.5 10.4 26.2 12.4 6.3 35.2 26.3 3.9 18.2 14.8 17.8 13.8 10.7 6.4 30.7 26.8 19.7 12.8 16.2 34.9 25.5 5.0 19.1 17.6 26.9 4.9 8.6 26.4 15.0 47.5 6.5 11.5 35.0 17.8 11.2 13.6 13.2 20.6 4.5 4.0 22.4 7.3 7.2 17.5 33.8 3.8 22.7 30.8 11.0 13.1 26.7 28.7 70.4 103.6 17.4 24.0 29.3 21.0 18.7 12.6 20.6 TRO "KIAA1114, MAGE-D3, MAGED3" ENSG00000067445 Trophinin Q12816 X 54920462-54931431 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 31.1" "Cell type enhanced" "Detected in many" "Astrocytes: 9.4;Excitatory neurons: 14.6;Granulosa cells: 12.3;Inhibitory neurons: 20.0;Oligodendrocyte precursor cells: 17.1;Oligodendrocytes: 9.4" "Cancer enhanced" "Detected in many" "testis cancer: 11.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 2.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "AF22: 37.1;SH-SY5Y: 33.8;SuSa: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071449 Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 36: Stromal cells - Cell proliferation" Vesicles "Plasma membrane, Cytosol" "HPA071449: " "unprognostic (6.18e-2)" "unprognostic (1.01e-1)" "unprognostic (2.24e-2)" "prognostic unfavorable (4.41e-5)" "unprognostic (9.09e-3)" "unprognostic (2.72e-1)" "unprognostic (5.66e-2)" "unprognostic (1.46e-1)" "unprognostic (4.67e-2)" "unprognostic (3.18e-1)" "prognostic favorable (1.93e-4)" "unprognostic (1.17e-1)" "unprognostic (3.19e-2)" "unprognostic (1.67e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (6.86e-2)" 3.9 3.0 13.9 1.3 10.6 1.0 3.7 0.8 23.7 9.5 0.9 3.2 0.9 13.4 6.6 1.6 5.3 4.2 2.4 9.3 17.2 3.9 16.8 2.1 1.6 6.2 5.1 17.5 7.1 5.3 24.4 4.3 6.9 5.5 2.1 6.2 1.5 5.2 31.1 1.2 1.6 8.6 3.4 1.0 2.0 2.6 12.6 4.7 10.1 1.0 1.6 2.5 5.5 13.3 0.0 0.3 37.1 0.1 7.1 9.8 0.0 2.1 13.1 2.0 0.7 0.0 0.0 0.0 5.3 13.8 3.1 0.2 0.3 0.6 1.0 0.1 23.3 18.0 0.0 1.5 2.7 0.0 0.1 22.8 0.0 12.0 0.0 11.8 0.9 9.1 0.0 0.2 14.0 0.0 0.3 0.1 19.6 0.1 0.0 11.3 16.4 0.1 3.5 0.3 25.3 33.8 0.0 0.5 3.1 74.2 0.0 2.2 0.0 15.7 15.9 0.2 2.2 5.8 0.9 0.0 2.3 0.0 13.8 0.0 0.0 0.0 0.4 0.0 0.2 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 2.2 0.1 0.9 0.0 0.1 13.9 10.6 0.8 23.7 9.3 17.2 6.2 5.1 6.9 3.4 12.6 13.3 0.4 0.0 0.0 9.4 0.3 0.4 1.4 0.8 5.2 4.2 0.5 1.9 1.8 0.0 1.9 3.7 0.0 0.8 0.2 0.0 0.0 1.7 0.4 0.3 7.9 1.9 0.0 0.0 14.6 0.2 0.6 7.0 0.5 0.5 1.3 12.3 0.4 0.0 0.5 8.4 20.0 0.0 0.0 0.0 0.4 0.6 5.9 0.2 0.0 1.0 0.1 2.2 0.0 17.1 9.4 0.2 0.0 3.8 0.1 0.4 0.0 0.4 0.0 0.9 0.0 1.5 3.3 1.2 1.9 0.1 0.1 0.7 0.7 2.9 0.0 0.3 TRPM1 "CSNB1C, LTRPC1, MLSN1" ENSG00000134160 "Transient receptor potential cation channel subfamily M member 1" Q7Z4N2 15 31001061-31161273 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Sensory transduction, Transport, Vision" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "retina: 9.4;skin 1: 4.1" "Group enriched" "Detected in some" 7 "Bipolar cells: 627.4;Melanocytes: 158.3" "Cancer enriched" "Detected in single" 179 "melanoma: 14.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 112 "SK-MEL-30: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014779, HPA071139" Enhanced Uncertain "Golgi apparatus,Plasma membrane,Centriolar satellite" NA NA "Cluster 77: Retina - Visual perception" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 56: Bipolar cells - Visual perception" "Centriolar satellite" "Golgi apparatus, Plasma membrane" "HPA014779: AB_2669090, HPA071139: " "unprognostic (5.28e-2)" "unprognostic (1.35e-1)" "unprognostic (9.89e-2)" "unprognostic (3.07e-1)" "unprognostic (1.97e-1)" "unprognostic (1.70e-1)" "unprognostic (1.29e-3)" "unprognostic (2.83e-1)" "unprognostic (2.89e-2)" "unprognostic (1.67e-1)" "unprognostic (1.45e-2)" "unprognostic (2.58e-1)" "unprognostic (7.84e-2)" "unprognostic (6.20e-4)" "unprognostic (1.48e-1)" "unprognostic (2.63e-2)" 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 9.4 0.1 0.0 0.0 4.1 0.0 0.0 0.5 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.1 0.2 0.2 0.4 0.3 0.5 0.3 0.5 0.0 0.0 0.0 0.7 0.0 4.2 0.0 0.0 0.0 627.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 50.5 0.1 0.1 1.7 0.0 0.0 0.9 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 13.5 0.8 0.0 0.0 0.0 1.0 6.3 0.0 0.0 158.3 0.0 0.0 11.0 0.0 0.0 19.4 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 22.2 0.0 0.1 0.1 10.1 4.4 1.8 1.0 1.0 0.0 0.0 0.0 0.1 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TRPM7 "CHAK1, LTRPC7, TRP-PLIK" ENSG00000092439 "Transient receptor potential cation channel subfamily M member 7" Q96QT4 15 50552473-50686797 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Necrosis, Transport" "Calcium channel, Ion channel, Kinase, Serine/threonine-protein kinase, Transferase" "Amyotrophic lateral sclerosis, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 108.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 122.2;Oligodendrocytes: 109.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 122.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035522, HPA052173" Enhanced Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 18: U-2197 - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Vesicles, Cytosol" "HPA035522: , HPA052173: AB_2681749" "unprognostic (3.14e-2)" "unprognostic (1.86e-1)" "unprognostic (1.58e-1)" "unprognostic (1.42e-2)" "unprognostic (1.89e-1)" "unprognostic (1.60e-2)" "unprognostic (1.85e-2)" "unprognostic (2.59e-2)" "unprognostic (5.46e-3)" "unprognostic (2.64e-1)" "unprognostic (2.91e-1)" "unprognostic (1.59e-2)" "unprognostic (3.20e-2)" "unprognostic (2.08e-1)" "unprognostic (7.59e-2)" "unprognostic (9.45e-2)" "unprognostic (1.97e-1)" 11.5 9.6 4.3 13.3 6.5 21.4 13.6 15.4 6.7 10.3 29.3 13.8 14.4 12.7 14.6 8.6 9.4 11.1 15.5 4.8 3.5 22.9 25.3 11.6 16.6 4.9 3.9 16.4 12.2 108.9 5.3 13.3 5.9 10.9 14.4 10.5 10.9 10.6 7.8 16.6 13.1 11.4 3.2 12.2 13.6 9.9 6.4 15.5 17.3 9.1 14.4 11.4 8.1 10.4 21.4 21.0 17.2 19.1 48.5 36.2 20.9 26.4 36.7 16.5 21.6 29.1 11.6 46.4 12.7 30.8 42.5 35.1 23.3 19.5 23.4 26.0 13.7 37.1 31.5 15.4 44.0 38.8 27.6 33.9 22.4 18.8 35.0 24.0 13.5 28.8 42.6 34.5 30.4 33.7 25.1 18.8 13.0 29.4 12.8 27.2 23.7 22.7 23.0 49.9 14.2 18.1 18.2 28.7 35.8 30.1 18.0 41.6 20.7 26.1 12.4 122.4 30.8 23.3 54.9 44.0 28.4 77.5 24.8 1.8 1.3 1.6 2.5 1.3 2.9 2.2 1.8 1.7 1.5 2.3 1.6 1.9 1.7 2.4 1.4 1.9 2.0 0.8 4.3 6.5 15.4 6.7 4.8 3.5 4.9 3.9 5.9 3.2 6.4 10.4 23.9 19.2 31.3 73.1 36.4 31.6 17.2 11.0 44.9 21.9 18.8 11.9 25.9 21.5 8.2 12.9 12.5 23.0 38.4 17.0 3.9 11.7 33.3 21.6 27.1 19.7 18.5 29.6 122.2 12.7 9.4 26.1 37.8 23.1 17.7 26.0 14.6 43.9 14.6 21.9 92.7 19.5 6.1 22.4 19.8 26.0 26.4 26.5 19.6 66.5 24.2 8.5 29.9 80.9 109.1 15.5 13.9 20.3 33.2 24.9 23.4 11.0 19.3 22.6 13.1 30.0 22.0 23.1 23.6 25.7 24.2 16.3 34.5 22.2 20.4 11.1 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TRPV3 VRL3 ENSG00000167723 "Transient receptor potential cation channel subfamily V member 3" Q8NET8 17 3510502-3557812 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Disease variant, FDA approved drug targets, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 5.2;skin 1: 4.8" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 18.7;Plasma cells: 15.9;Proximal enterocytes: 26.1;Suprabasal keratinocytes: 24.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 3.3;BEWO: 5.0;CACO-2: 3.1;RH-30: 11.9;T-47d: 5.2;U-266/70: 3.1;U-266/84: 2.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069550 Approved "Plasma membrane,Centrosome,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "Centrosome, Cytosol" "HPA069550: AB_2686149" "unprognostic (1.84e-4)" "unprognostic (2.25e-1)" "unprognostic (5.22e-2)" "unprognostic (3.92e-4)" "unprognostic (4.87e-3)" "unprognostic (2.96e-2)" "unprognostic (6.66e-2)" "unprognostic (4.88e-2)" "unprognostic (7.02e-2)" "unprognostic (2.68e-1)" "unprognostic (4.88e-2)" "unprognostic (3.69e-2)" "unprognostic (0.00e+0)" "unprognostic (1.12e-1)" "unprognostic (1.77e-1)" "unprognostic (8.64e-2)" "unprognostic (2.93e-2)" 0.1 0.0 1.1 0.5 1.1 0.5 0.2 0.1 1.1 0.3 0.0 0.9 2.0 0.0 0.1 0.2 0.0 0.1 0.0 0.6 0.3 0.0 0.6 0.1 0.3 0.4 0.3 0.2 0.0 0.1 0.3 0.2 0.4 0.1 1.7 0.2 0.1 0.0 1.5 4.8 5.2 0.1 0.1 0.2 0.9 0.4 0.9 0.0 0.0 0.5 0.5 0.2 0.3 1.8 3.3 0.0 0.3 0.0 0.2 0.3 5.0 0.1 0.0 0.0 0.0 3.1 0.8 0.1 1.0 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.4 0.0 0.1 0.5 0.2 0.0 0.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.1 0.2 0.4 0.1 11.9 0.1 0.0 0.1 0.0 0.0 0.1 0.5 0.0 0.0 5.2 0.1 0.0 0.0 0.1 0.1 0.0 3.1 2.7 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.1 1.1 0.1 1.1 0.6 0.3 0.4 0.3 0.4 0.1 0.9 1.8 0.2 0.0 2.5 2.9 5.8 18.7 3.9 0.2 10.2 1.2 0.9 0.5 3.5 1.5 0.2 0.0 0.0 0.3 2.6 8.9 1.9 0.0 0.3 0.7 0.9 1.6 0.0 0.0 1.6 0.0 0.9 3.7 6.1 0.9 0.0 1.1 0.0 0.3 0.3 5.0 0.6 2.7 0.0 0.0 3.8 0.4 3.1 0.8 7.2 0.0 0.1 2.2 3.1 0.5 2.3 1.2 2.5 3.4 15.9 5.9 26.1 2.3 0.2 1.0 0.0 6.9 1.8 0.0 1.5 2.9 24.6 0.5 1.8 2.8 0.9 3.7 TSG101 "TSG10, VPS23" ENSG00000074319 "Tumor susceptibility 101" Q99816 11 18468336-18526951 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Growth regulation, Host-virus interaction, Protein transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 296.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004283, HPA006161" Approved Supported "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 10: Non-specific - Unknown function" Cytosol "Nucleoli, Plasma membrane" "CAB004283: AB_671392, HPA006161: AB_1080408" "unprognostic (1.42e-1)" "unprognostic (7.91e-2)" "unprognostic (2.11e-1)" "unprognostic (6.77e-2)" "unprognostic (1.82e-1)" "unprognostic (2.72e-3)" "prognostic unfavorable (3.74e-6)" "unprognostic (5.67e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-2)" "unprognostic (4.15e-3)" "unprognostic (4.27e-2)" "prognostic favorable (5.52e-6)" "unprognostic (1.92e-2)" "unprognostic (1.02e-1)" "unprognostic (4.02e-3)" "unprognostic (1.06e-1)" 40.4 55.6 41.1 32.2 42.2 60.8 56.6 43.1 50.8 44.8 45.7 49.5 42.8 40.2 56.3 56.7 49.3 36.5 68.2 42.1 44.5 70.1 62.3 43.9 42.9 42.4 42.3 44.6 45.4 61.5 36.5 61.4 42.4 43.1 59.0 43.6 46.4 41.1 77.1 47.2 43.4 42.9 43.9 34.0 45.4 55.5 41.8 45.9 52.4 83.0 57.4 46.9 42.2 46.5 51.3 79.1 73.7 51.1 82.2 85.4 63.7 77.1 103.0 92.2 90.3 54.3 27.5 65.5 49.2 86.4 103.7 77.0 74.0 70.3 102.0 95.4 87.7 41.1 38.6 79.7 106.3 64.6 69.8 75.0 139.9 48.6 131.6 102.2 76.8 68.4 66.9 55.2 112.7 85.7 45.7 66.8 45.1 115.6 81.5 37.0 72.5 54.7 63.6 68.8 52.2 88.6 75.7 61.6 101.1 77.1 59.7 64.8 43.1 63.0 38.0 126.4 59.4 37.2 76.0 56.9 64.5 34.2 80.5 187.8 69.8 155.7 50.4 81.6 52.4 78.5 48.0 54.0 66.1 69.2 51.5 54.9 123.6 57.9 114.3 54.5 84.4 91.1 41.1 42.2 43.1 50.8 42.1 44.5 42.4 42.3 42.4 43.9 41.8 46.5 63.0 64.1 57.5 22.9 44.4 42.6 81.5 159.2 26.7 41.0 39.2 42.2 68.0 42.9 90.4 44.1 25.0 191.9 34.2 85.5 125.2 112.4 48.0 58.4 36.0 54.4 61.6 74.5 29.1 101.3 107.7 48.6 32.6 48.9 44.9 46.2 47.2 36.0 79.6 37.0 28.4 65.0 156.6 45.2 33.6 21.2 56.2 51.6 56.9 26.2 82.3 86.1 54.6 32.2 32.8 132.7 76.2 43.2 47.0 103.0 72.2 126.8 113.4 43.3 46.0 44.7 81.2 177.6 153.7 32.8 48.4 296.1 38.1 91.5 47.8 97.4 TSGA13 ENSG00000213265 "Testis specific 13" Q96PP4 7 130668643-130687432 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 103 "testis: 14.0" "Group enriched" "Detected in some" 18 "Early spermatids: 86.4;Late spermatids: 224.1" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA022968 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane, Cytosol" "HPA022968: AB_2671013" "unprognostic (1.49e-1)" "unprognostic (1.13e-2)" "unprognostic (1.86e-1)" "unprognostic (1.34e-1)" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 3.2 3.9 0.0 0.3 1.7 0.1 0.0 0.0 1.2 0.3 0.1 0.1 0.0 1.9 0.0 8.4 0.1 0.3 0.0 0.0 0.0 86.4 0.3 0.3 1.0 0.0 0.0 0.2 0.0 0.0 2.0 0.0 0.4 0.0 0.4 0.7 0.0 0.1 0.0 0.2 0.0 0.0 0.9 2.2 224.1 0.6 0.8 0.0 0.0 0.1 0.6 1.0 0.5 0.1 0.0 0.0 0.7 0.3 0.0 0.0 0.0 6.0 1.5 0.0 0.0 0.3 1.6 0.6 0.0 0.4 0.7 0.6 0.1 0.0 0.0 TSHZ3 "KIAA1474, TSH3, ZNF537" ENSG00000121297 "Teashirt zinc finger homeobox 3" Q63HK5 19 31149979-31349436 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 32.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.0;Excitatory neurons: 34.4;Inhibitory neurons: 84.7;Oligodendrocyte precursor cells: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.2;RH-30: 46.4;U-138 MG: 32.8;U-87 MG: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008834, HPA071010" Approved Enhanced "Nucleoplasm,Plasma membrane" No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane" "HPA008834: AB_1080731, HPA071010: " "unprognostic (2.56e-1)" "unprognostic (3.88e-1)" "unprognostic (4.56e-2)" "unprognostic (3.66e-1)" "unprognostic (1.66e-3)" "unprognostic (4.07e-2)" "unprognostic (1.67e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (3.58e-3)" "unprognostic (2.23e-1)" "unprognostic (3.91e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (8.76e-3)" "unprognostic (8.22e-2)" "unprognostic (1.91e-2)" "unprognostic (1.73e-3)" 7.0 3.6 4.6 4.8 4.5 1.1 6.2 0.0 8.6 18.8 0.3 16.1 2.2 21.5 9.2 5.7 13.0 9.3 5.7 5.7 0.4 3.2 1.3 6.3 1.2 3.1 1.0 32.8 1.5 1.3 4.6 5.7 1.5 11.6 4.0 1.8 3.3 9.5 1.9 3.0 5.5 18.4 3.9 5.4 6.7 2.7 3.1 0.8 10.2 2.3 0.5 14.8 8.8 4.9 0.0 2.0 0.7 0.0 9.4 22.2 0.0 6.0 8.8 3.7 6.6 0.0 1.2 0.0 0.0 14.8 7.0 1.0 2.7 5.3 8.2 0.0 2.2 0.0 0.0 0.0 19.4 5.2 9.1 13.0 4.5 13.7 6.8 0.0 0.0 4.4 0.0 0.0 16.9 0.9 0.0 0.0 0.7 0.0 0.0 5.9 46.4 0.0 0.0 0.0 0.0 13.8 0.1 0.0 4.7 4.4 0.0 3.6 0.0 32.8 10.3 3.4 8.8 0.0 0.0 0.0 21.2 8.8 0.9 0.0 0.9 0.0 1.1 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.3 1.9 0.0 0.1 0.0 0.3 0.3 4.6 4.5 0.0 8.6 5.7 0.4 3.1 1.0 1.5 3.9 3.1 4.9 8.3 3.2 1.1 10.1 0.2 4.8 7.3 9.2 15.4 14.0 0.8 2.4 2.1 1.5 5.1 3.7 0.0 0.4 2.5 0.0 0.0 0.4 0.2 1.3 54.0 9.0 0.0 0.4 34.4 0.6 0.3 20.2 0.0 1.3 1.3 2.6 17.2 0.2 11.6 16.8 84.7 0.0 2.0 9.7 10.4 1.1 17.7 5.0 5.4 14.0 6.4 0.2 0.0 59.3 1.9 0.6 0.0 29.3 0.3 3.8 0.0 0.1 1.3 0.2 0.0 29.7 7.8 0.3 4.0 1.7 1.7 0.8 1.7 1.0 0.0 3.2 TSPAN15 "NET-7, TM4SF15" ENSG00000099282 "Tetraspanin 15" O95858 10 69451465-69507666 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 125.8;Ductal cells: 125.2;Exocrine glandular cells: 189.3;Pancreatic endocrine cells: 193.4;Paneth cells: 120.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "MAIT T-cell: 19.5" "Lineage enriched" "Detected in many" 6 "T-cells: 19.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 154.7;EFO-21: 211.3;MCF7: 168.0;OE19: 153.2;PC-3: 266.8;SK-BR-3: 134.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044657, HPA071160" Approved Approved "Nuclear bodies,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 38: EFO-21 - Unknown function" "Cluster 1: Pancreatic cells - Digestion" "Nuclear bodies, Plasma membrane" "Vesicles, Cytosol" "HPA044657: AB_10967927, HPA071160: " "unprognostic (2.03e-1)" "unprognostic (1.28e-1)" "unprognostic (1.43e-1)" "unprognostic (1.48e-2)" "unprognostic (9.44e-3)" "unprognostic (6.81e-3)" "prognostic unfavorable (8.00e-4)" "unprognostic (2.23e-1)" "unprognostic (3.65e-1)" "unprognostic (2.76e-1)" "unprognostic (8.22e-3)" "unprognostic (2.36e-2)" "prognostic unfavorable (1.25e-4)" "unprognostic (8.49e-2)" "unprognostic (4.66e-2)" "unprognostic (6.34e-2)" "unprognostic (3.78e-3)" 70.1 5.3 22.8 15.3 37.6 1.0 61.0 35.0 34.1 16.4 14.9 62.5 38.8 32.6 8.5 10.8 24.6 27.4 16.9 23.6 25.4 25.9 4.6 34.4 8.7 36.9 33.4 3.4 20.0 3.2 6.6 28.1 33.7 34.5 39.4 3.1 26.6 24.7 17.9 10.6 38.8 31.3 30.0 26.7 75.3 9.5 34.5 3.6 14.5 5.6 7.5 46.0 14.9 62.4 51.3 103.9 2.1 0.3 2.3 0.0 12.0 0.2 1.9 2.6 6.8 45.1 154.7 0.0 211.3 2.3 9.2 101.2 7.2 11.5 3.0 42.1 20.4 2.9 3.5 10.0 1.1 0.1 1.8 2.2 3.1 1.4 1.5 7.5 39.4 20.5 1.1 0.0 1.2 168.0 0.6 0.9 2.6 153.2 266.8 4.0 2.1 2.0 29.7 92.9 34.5 13.2 0.6 134.8 17.9 17.3 59.3 2.2 34.5 0.2 0.8 0.1 17.5 1.2 6.1 1.0 1.1 0.1 0.2 0.0 0.0 0.0 2.3 0.0 19.5 0.0 3.1 2.8 3.3 0.0 1.0 0.2 0.0 0.1 0.0 0.2 1.1 0.5 22.8 37.6 35.0 34.1 23.6 25.4 36.9 33.4 33.7 30.0 34.5 62.4 108.8 32.1 6.9 4.9 1.5 3.6 10.9 59.6 2.2 2.9 45.1 15.6 1.7 31.5 29.5 29.5 6.2 2.0 1.6 125.8 3.9 125.2 27.9 25.5 3.8 48.4 40.2 8.0 1.7 189.3 11.9 8.2 71.4 36.6 1.3 2.5 10.4 0.1 25.3 1.7 1.0 106.7 36.7 8.5 16.1 6.6 0.6 9.8 28.4 15.0 15.6 44.7 0.0 11.1 75.3 193.4 120.9 0.0 0.2 50.4 68.3 1.8 27.6 1.5 13.1 39.7 26.8 4.3 18.5 2.9 3.1 3.0 3.9 7.5 66.3 29.6 TSPAN16 "TM-8, TM4-B, TM4SF16" ENSG00000130167 "Tetraspanin 16" Q9UKR8 19 11296139-11326996 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 134.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 4868.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 16.6;eosinophil: 19.1;neutrophil: 37.4" "Lineage enriched" "Detected in many" 17 "granulocytes: 37.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA076551 Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA076551: " "unprognostic (1.06e-1)" "unprognostic (2.82e-2)" "unprognostic (1.73e-2)" "unprognostic (4.74e-3)" "unprognostic (1.53e-1)" "unprognostic (2.06e-3)" "unprognostic (1.37e-1)" "unprognostic (2.21e-1)" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (8.69e-4)" "unprognostic (8.81e-8)" "unprognostic (1.98e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-3)" "unprognostic (2.67e-1)" 0.0 0.0 0.2 0.2 0.1 5.1 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 134.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.6 2.2 19.1 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 37.4 0.0 0.4 0.0 0.0 0.3 0.2 0.1 0.3 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 892.5 0.0 0.1 1.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 4868.3 15.5 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.4 20.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPAN6 "T245, TM4SF6, TSPAN-6" ENSG00000000003 "Tetraspanin 6" O43657 X 100627108-100639991 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 422.5;Granulosa cells: 684.8;Late spermatids: 1708.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 2.1" "Lineage enriched" "Detected in single" 6 "T-cells: 2.1" "Cell line enhanced" "Detected in many" "NTERA-2: 121.7;RT4: 153.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA004109 Approved Approved "Nucleoli fibrillar center,Cell Junctions,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 40: Granulosa cells - Unknown function" "Cell Junctions, Cytosol" "Nucleoli fibrillar center" "HPA004109: AB_1080301" "unprognostic (7.71e-2)" "unprognostic (8.97e-2)" "unprognostic (3.56e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-3)" "unprognostic (5.93e-2)" "unprognostic (1.04e-1)" "unprognostic (1.09e-2)" "unprognostic (1.19e-2)" "unprognostic (1.80e-3)" "unprognostic (2.04e-3)" "unprognostic (8.76e-2)" "unprognostic (3.83e-3)" "unprognostic (4.28e-2)" "unprognostic (1.14e-1)" "unprognostic (2.24e-1)" "unprognostic (9.54e-3)" 29.6 18.2 7.2 4.9 7.5 0.6 34.2 7.2 8.9 26.9 26.8 40.0 19.7 20.5 14.8 46.8 39.5 16.7 8.6 7.4 9.0 36.5 70.2 11.3 3.0 8.7 9.3 53.4 20.2 34.7 36.9 20.0 8.2 18.9 33.1 6.2 52.6 10.3 4.6 9.7 18.5 7.2 8.9 8.7 14.8 74.9 9.6 4.2 19.3 5.3 6.8 32.2 24.1 12.0 24.8 23.0 80.6 42.2 28.7 16.6 30.4 12.9 17.3 20.3 47.6 54.9 37.7 0.0 53.3 12.2 16.9 19.9 0.3 19.7 25.8 0.1 33.3 3.8 14.9 62.0 17.1 0.1 2.5 30.2 9.3 19.5 6.6 34.4 49.3 0.0 0.0 0.1 21.7 19.8 0.1 0.3 121.7 35.4 18.4 0.0 35.5 0.0 33.0 153.5 4.7 20.3 11.6 10.0 18.5 61.9 16.6 3.3 12.7 16.0 24.4 24.3 8.6 0.1 0.2 0.3 13.4 0.0 11.5 0.3 0.0 0.1 0.3 0.0 1.1 0.1 0.8 0.3 0.0 0.1 2.1 1.2 0.3 0.1 0.1 0.1 0.0 0.3 7.2 7.5 7.2 8.9 7.4 9.0 8.7 9.3 8.2 8.9 9.6 12.0 147.0 3.2 10.1 14.4 2.3 7.1 41.0 75.7 29.0 0.6 72.5 46.1 8.2 50.1 89.4 93.8 0.0 28.7 1.1 94.9 23.5 80.3 422.5 54.0 21.4 37.4 33.6 4.8 0.9 12.6 40.7 25.6 21.9 19.2 0.0 684.8 47.5 104.0 4.5 0.0 0.8 47.9 193.3 10.2 3.1 1708.3 32.9 3.1 10.6 1.0 1.0 48.2 0.0 9.5 0.4 18.7 55.5 35.7 0.3 33.0 43.5 43.8 193.9 1.9 19.7 17.1 43.1 20.9 32.4 23.3 5.4 13.5 2.5 49.4 94.3 89.7 TSPO2 "BZRPL1, dJ34B21.2" ENSG00000112212 "Translocator protein 2" Q5TGU0 6 41042467-41044337 "Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 50.1" "Cell type enriched" "Detected in some" 115 "Erythroid cells: 253.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "OE19: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060691, HPA066996" Enhanced "Plasma membrane" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "HPA060691: , HPA066996: AB_2685761" "unprognostic (1.89e-3)" "unprognostic (8.35e-3)" "unprognostic (2.57e-3)" "unprognostic (2.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-2)" "unprognostic (6.61e-3)" "unprognostic (2.29e-1)" "unprognostic (3.37e-1)" "unprognostic (2.89e-1)" "unprognostic (2.71e-1)" "unprognostic (4.92e-2)" "unprognostic (1.86e-2)" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (5.37e-2)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.1 0.6 50.1 0.0 0.1 0.7 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.4 0.5 0.6 0.2 0.1 0.8 0.4 0.1 0.1 0.0 0.0 1.2 0.9 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.7 0.0 0.2 1.3 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.1 0.4 0.0 11.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.7 0.1 0.4 0.8 0.4 0.9 0.2 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.9 0.3 0.1 0.0 0.0 0.0 253.9 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 TSR2 "DT1P1A10, RP1-112K5.2, WGG1" ENSG00000158526 "TSR2 ribosome maturation factor" Q969E8 X 54440404-54448032 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "rRNA processing" "Diamond-Blackfan anemia, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030514 Approved Approved "Nucleoplasm,Nucleoli,Cell Junctions,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Nucleoplasm, Nucleoli" "Cell Junctions, Cytosol" "HPA030514: AB_10603457" "unprognostic (1.05e-1)" "unprognostic (1.80e-2)" "unprognostic (1.77e-2)" "unprognostic (1.58e-2)" "unprognostic (2.64e-2)" "unprognostic (5.91e-2)" "unprognostic (7.15e-3)" "unprognostic (8.29e-2)" "unprognostic (4.39e-1)" "unprognostic (1.31e-1)" "unprognostic (2.94e-2)" "unprognostic (6.19e-2)" "prognostic favorable (1.21e-6)" "unprognostic (2.27e-1)" "unprognostic (1.13e-1)" "unprognostic (7.93e-3)" "unprognostic (1.80e-3)" 35.2 45.1 50.9 11.2 49.9 11.9 35.6 43.4 59.4 36.8 39.3 42.2 10.2 34.9 23.0 34.6 32.2 7.7 45.5 46.2 52.9 43.8 36.7 30.4 12.6 48.9 48.0 34.6 30.2 25.0 47.1 14.6 47.3 33.3 13.3 27.4 32.6 16.9 51.7 40.7 31.3 13.2 50.3 32.4 38.8 16.5 50.6 14.9 41.1 18.6 15.8 36.3 35.0 47.8 24.1 26.6 23.9 20.6 19.9 13.0 18.7 22.4 17.5 19.6 17.3 26.2 24.1 23.5 15.8 18.2 35.7 24.9 47.9 28.3 24.8 29.8 26.8 19.3 20.8 19.6 12.5 32.7 19.4 12.9 18.0 26.4 27.1 19.7 13.8 22.9 20.5 16.9 19.3 37.9 27.4 29.9 34.6 23.6 33.0 26.5 38.2 19.6 20.6 18.3 25.9 20.5 42.1 19.9 28.0 38.0 45.4 14.7 21.0 16.2 27.1 38.0 19.9 19.8 32.3 29.7 24.4 27.5 23.2 29.7 16.6 32.0 36.3 23.1 30.0 44.8 34.0 33.6 15.1 46.3 42.6 32.3 10.4 29.7 26.0 16.7 40.8 24.9 50.9 49.9 43.4 59.4 46.2 52.9 48.9 48.0 47.3 50.3 50.6 47.8 39.1 25.6 30.2 1.6 39.8 32.8 43.0 42.7 26.7 61.6 27.4 28.6 49.0 28.6 38.6 35.0 27.1 98.5 36.0 26.3 125.2 43.9 1.2 17.7 23.7 35.6 18.1 18.1 5.7 32.9 71.5 33.8 16.8 22.9 45.0 20.3 31.8 25.2 46.6 57.2 5.6 35.5 61.1 18.2 31.4 2.8 34.8 24.6 40.9 6.5 48.6 85.6 44.3 2.5 6.5 38.1 29.5 45.1 22.3 36.7 32.6 64.6 33.8 67.0 46.0 29.8 38.0 20.5 43.3 25.4 31.7 75.9 37.8 36.2 30.9 33.9 TSSK4 "C14orf20, STK22E" ENSG00000139908 "Testis specific serine kinase 4" Q6SA08 14 24205696-24208362 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Spermatogenesis" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "testis: 38.1" "Cell type enriched" "Detected in some" 9 "Early spermatids: 253.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA060660, HPA077103" Approved Approved "Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Cell Junctions" "HPA060660: AB_2684339, HPA077103: AB_2732332" "unprognostic (1.95e-1)" "unprognostic (4.30e-2)" "unprognostic (1.52e-1)" "unprognostic (5.69e-2)" "unprognostic (2.36e-1)" "unprognostic (3.38e-5)" "unprognostic (1.06e-1)" "unprognostic (6.25e-3)" "unprognostic (1.64e-1)" "unprognostic (3.39e-1)" "unprognostic (7.03e-3)" "unprognostic (1.27e-3)" "unprognostic (3.42e-1)" "unprognostic (4.30e-2)" "unprognostic (6.28e-2)" "unprognostic (8.98e-2)" "unprognostic (7.26e-2)" 1.0 1.1 0.7 2.0 0.4 3.4 1.0 1.0 0.3 1.4 0.0 1.4 1.6 1.1 0.3 1.3 1.2 1.6 0.7 0.6 0.1 0.8 0.6 1.0 2.7 0.3 0.3 1.1 1.5 0.0 0.9 0.4 0.3 0.9 0.0 3.1 1.5 0.0 1.3 4.2 1.7 0.0 0.2 1.7 1.2 38.1 0.3 0.0 1.4 0.0 0.0 1.1 1.1 0.3 0.6 2.3 2.2 0.8 0.0 0.0 2.4 0.9 0.0 0.0 0.0 1.3 2.2 1.8 0.5 0.1 0.4 2.1 0.0 0.1 0.0 0.9 1.7 2.0 3.4 1.7 0.0 1.0 2.1 0.0 0.0 0.0 0.3 1.9 0.0 2.1 0.8 1.2 0.0 2.2 2.1 1.1 0.4 0.5 1.8 1.8 0.8 1.5 0.0 3.0 1.2 1.2 1.7 1.4 0.4 0.9 1.0 1.0 0.9 1.6 1.0 2.1 0.7 2.3 3.0 2.6 0.5 1.6 0.5 0.0 0.2 0.4 0.4 0.2 0.1 0.3 0.3 0.3 0.1 0.3 0.3 0.3 0.3 0.5 0.1 0.3 0.1 0.1 0.7 0.4 1.0 0.3 0.6 0.1 0.3 0.3 0.3 0.2 0.3 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 253.7 0.3 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 26.5 1.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.1 0.1 0.3 0.1 0.8 0.0 0.0 0.2 0.1 6.8 0.8 0.0 0.0 0.1 0.1 0.1 0.0 0.0 TTC17 FLJ10890 ENSG00000052841 "Tetratricopeptide repeat domain 17" Q96AE7 11 43358920-43494933 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038508 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "HPA038508: AB_10671744" "unprognostic (2.71e-1)" "unprognostic (4.04e-3)" "unprognostic (6.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.17e-1)" "unprognostic (5.66e-2)" "unprognostic (1.74e-1)" "unprognostic (9.03e-2)" "unprognostic (5.01e-3)" "unprognostic (2.62e-1)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.75e-6)" "unprognostic (1.04e-2)" "unprognostic (4.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-2)" 20.7 18.7 11.0 16.1 11.3 15.5 28.6 16.7 12.2 22.0 22.0 21.2 21.6 26.9 25.0 14.2 28.4 22.3 13.5 11.1 12.2 19.4 38.6 24.2 20.2 11.9 12.5 40.9 49.5 27.7 12.3 29.2 11.7 25.4 22.9 25.1 40.7 21.4 16.4 19.5 25.5 23.0 11.0 23.4 27.4 24.8 12.4 24.6 36.9 20.0 22.4 18.8 15.6 13.0 15.0 30.4 31.3 49.3 77.2 63.6 22.1 35.6 47.6 29.3 35.1 21.1 21.7 31.6 34.9 35.9 33.7 31.1 22.3 23.5 35.2 24.5 29.0 24.2 19.5 20.8 95.3 36.6 29.9 59.5 69.8 21.3 68.4 66.2 29.5 22.7 35.5 26.2 29.8 18.1 27.1 20.3 46.8 58.0 25.0 25.1 33.3 36.9 37.2 21.4 16.7 39.7 27.7 73.1 44.6 31.4 68.6 40.8 39.6 41.7 18.4 47.1 52.1 51.1 44.5 29.8 26.9 21.6 45.3 20.0 21.7 19.0 14.9 22.4 15.9 16.4 16.2 14.5 16.9 14.8 16.3 15.1 18.5 16.5 20.8 17.6 16.1 18.0 11.0 11.3 16.7 12.2 11.1 12.2 11.9 12.5 11.7 11.0 12.4 13.0 43.0 64.1 62.7 159.6 53.3 42.1 35.0 36.4 30.7 44.1 40.3 35.7 20.5 31.5 51.9 22.0 60.5 32.6 43.8 30.7 3.9 23.1 52.6 35.8 44.5 40.9 22.3 44.0 204.6 43.4 28.8 44.4 40.2 48.6 36.6 56.2 40.0 57.5 26.2 47.1 203.2 42.1 34.6 48.0 32.3 18.4 57.2 37.1 28.4 181.8 47.8 24.8 37.0 192.0 200.6 29.7 31.5 36.5 48.9 50.1 47.7 15.5 54.3 47.3 52.6 45.5 36.2 51.8 35.0 34.6 43.2 30.8 45.6 33.5 35.8 42.7 TTC7B TTC7L1 ENSG00000165914 "Tetratricopeptide repeat domain 7B" Q86TV6 14 90524564-90816479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 88.8;Excitatory neurons: 116.7;Inhibitory neurons: 132.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.6;eosinophil: 8.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 72.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058363, HPA059577" Enhanced Supported "Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA058363: AB_2683692, HPA059577: AB_2684069" "unprognostic (9.37e-2)" "unprognostic (4.20e-2)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.58e-1)" "unprognostic (2.67e-4)" "unprognostic (9.42e-2)" "unprognostic (2.17e-1)" "unprognostic (5.38e-2)" "unprognostic (7.60e-2)" "unprognostic (2.75e-3)" "unprognostic (2.87e-2)" "prognostic favorable (3.20e-6)" "unprognostic (2.74e-2)" "unprognostic (7.41e-2)" "unprognostic (4.48e-2)" "unprognostic (1.07e-2)" 23.7 11.6 42.9 9.1 43.4 10.2 18.1 47.1 57.2 20.1 0.7 37.9 5.0 24.2 6.1 15.5 18.0 9.2 33.2 51.0 18.7 16.9 17.6 18.5 4.1 35.7 32.2 15.8 24.7 15.7 18.2 18.4 38.7 16.1 4.4 14.4 12.8 13.9 60.9 9.3 11.0 17.6 14.6 15.4 22.4 4.2 45.2 3.5 9.5 27.9 2.7 25.4 13.1 39.6 19.4 17.2 20.0 14.8 18.2 21.5 65.5 15.5 13.2 20.2 21.7 4.5 5.1 0.2 23.6 17.4 23.9 0.4 13.1 10.8 19.6 35.3 14.1 43.6 8.9 4.1 18.3 1.0 72.8 16.1 7.1 10.9 13.2 18.5 29.4 16.9 24.7 35.3 19.7 20.5 0.5 17.2 11.4 1.1 14.8 37.8 33.0 6.6 6.6 14.4 30.5 20.9 15.4 6.3 33.3 12.7 9.0 13.3 33.7 20.6 16.1 15.2 25.4 12.0 6.3 0.2 29.6 4.1 20.6 5.6 0.2 8.0 0.1 0.5 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.1 1.0 0.3 0.1 0.5 0.9 0.5 42.9 43.4 47.1 57.2 51.0 18.7 35.7 32.2 38.7 14.6 45.2 39.6 13.1 3.2 1.1 88.8 0.5 2.8 2.1 1.1 0.6 13.4 2.7 2.8 21.6 2.8 0.4 5.5 16.7 13.1 0.6 0.1 1.9 2.3 5.9 1.3 5.2 7.9 1.2 2.5 116.7 2.4 7.4 7.3 0.5 2.0 7.6 20.0 10.8 9.9 8.1 30.3 132.8 0.1 4.1 5.6 4.3 3.2 6.8 7.2 12.4 36.5 2.7 6.0 0.0 69.9 70.7 0.8 0.1 7.2 0.4 3.0 0.3 4.0 5.5 17.8 26.3 9.9 9.2 1.7 1.6 0.7 2.0 30.1 1.1 2.1 0.0 1.2 TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 104.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.3;Paneth cells: 56.9;Squamous epithelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB046029: AB_11128395, HPA003054: AB_2666770" "unprognostic (2.45e-2)" "unprognostic (3.47e-2)" "unprognostic (7.37e-3)" "unprognostic (5.40e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (5.81e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-3)" "unprognostic (1.40e-1)" "unprognostic (6.66e-2)" "unprognostic (2.81e-2)" 13.9 28.1 8.7 16.6 8.5 26.2 13.0 10.0 15.1 25.8 1.8 35.6 24.4 13.9 3.6 104.5 13.9 18.5 10.2 9.5 9.7 9.0 21.0 9.3 11.2 16.2 8.7 23.7 19.2 9.4 14.7 7.2 15.8 15.2 19.5 4.7 21.9 6.8 12.6 36.8 22.9 7.1 6.5 10.7 33.4 25.7 8.1 8.0 9.1 7.9 12.9 15.5 37.0 9.1 113.2 46.7 18.5 45.9 27.8 19.0 59.7 36.3 12.8 34.1 17.8 76.2 62.7 107.9 43.0 30.3 16.7 78.8 77.3 66.5 8.7 13.6 123.3 26.5 73.6 66.4 43.5 120.2 26.4 30.2 79.3 40.8 43.4 18.3 36.5 52.1 166.1 24.8 16.1 104.4 84.1 65.2 67.4 78.9 46.1 84.4 63.5 155.6 28.7 36.6 56.2 23.2 77.1 111.2 41.6 8.4 44.0 52.9 35.2 22.7 31.7 44.1 51.4 41.6 55.4 81.0 25.7 60.8 31.4 0.0 2.3 0.3 2.6 1.2 2.5 1.8 2.5 1.9 1.8 1.1 2.4 1.7 0.6 2.3 1.7 1.6 1.8 1.9 8.7 8.5 10.0 15.1 9.5 9.7 16.2 8.7 15.8 6.5 8.1 9.1 3.7 6.4 6.7 3.6 6.4 11.2 11.4 11.0 17.1 8.5 13.5 9.9 4.5 17.2 7.6 7.3 4.2 8.8 3.2 56.3 5.9 14.2 1.0 5.0 9.5 5.8 9.1 39.1 8.0 8.6 19.0 6.0 34.1 14.7 0.0 14.3 8.2 35.0 9.8 0.0 8.5 30.6 10.2 14.2 2.9 2.6 8.7 7.5 10.6 1.9 7.7 4.2 4.1 3.0 2.2 25.8 56.9 17.0 9.4 28.7 32.1 8.3 5.0 5.6 0.0 5.2 7.2 2.0 12.2 60.2 18.2 4.1 5.9 13.4 39.9 13.7 TTLL5 KIAA0998 ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2;Early spermatids: 111.0;Excitatory neurons: 134.3;Inhibitory neurons: 114.2;Oligodendrocytes: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032128 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA032128: AB_10600835" "unprognostic (7.35e-2)" "unprognostic (7.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (5.96e-2)" "unprognostic (7.21e-5)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (7.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-1)" "unprognostic (5.67e-3)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (8.97e-2)" "unprognostic (2.15e-2)" 5.5 5.5 3.7 6.0 6.0 11.7 7.1 7.1 7.2 7.3 15.0 6.2 4.7 8.0 7.2 7.8 11.6 6.5 5.8 3.8 6.6 6.2 4.1 6.5 5.1 10.5 6.4 7.1 4.9 11.1 5.4 7.5 10.6 6.9 7.3 23.9 6.5 6.9 4.7 7.1 4.5 8.6 6.4 4.1 5.9 57.4 6.4 10.1 7.8 5.8 7.5 6.1 6.4 12.0 22.8 16.2 13.9 14.5 10.9 16.8 12.9 13.1 15.9 15.4 19.9 10.3 20.8 6.4 7.2 13.9 11.3 21.3 12.3 21.7 29.3 7.6 7.3 12.5 16.8 11.3 9.3 9.2 11.5 13.1 10.6 19.4 21.5 16.8 33.8 17.5 7.2 10.5 15.7 32.1 15.6 12.6 9.9 18.0 16.6 9.5 19.6 8.8 15.0 22.2 18.4 11.6 27.5 20.2 6.8 11.0 27.6 9.8 38.1 20.5 18.0 18.5 12.2 8.8 13.5 14.6 20.7 10.4 13.9 11.6 2.0 1.7 2.6 2.0 2.4 2.3 2.5 2.7 3.2 1.8 2.9 2.7 2.4 2.3 2.5 3.4 2.2 1.4 3.7 6.0 7.1 7.2 3.8 6.6 10.5 6.4 10.6 6.4 6.4 12.0 7.1 3.2 10.1 71.8 6.1 5.0 5.5 5.4 8.0 10.9 17.3 11.6 8.7 17.2 10.2 11.0 127.2 8.1 8.5 7.6 3.9 7.1 111.0 37.4 11.9 10.7 7.7 5.0 134.3 5.3 13.2 9.3 8.6 10.8 12.6 11.7 19.6 7.4 5.6 0.0 114.2 6.5 16.2 5.8 5.1 93.1 12.5 6.6 5.4 82.4 8.5 10.0 6.2 78.4 242.9 6.1 11.9 11.7 7.6 6.2 6.0 2.4 40.1 80.1 13.1 9.5 6.0 37.7 16.4 9.0 6.3 6.0 8.3 9.1 8.0 4.6 TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.9;choroid plexus: 35.6;testis: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Bipolar cells: 138.6;Muller glia cells: 653.4;Oligodendrocytes: 97.5;Rod photoreceptor cells: 155.3" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;AN3-CA: 11.7;U-2 OS: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" 0.9 0.9 64.3 0.0 67.9 0.0 3.5 64.0 80.9 4.0 35.6 10.0 0.2 1.6 0.0 1.1 10.4 0.2 3.6 57.6 59.7 1.2 0.7 0.2 0.0 69.4 66.5 1.5 19.4 0.0 17.7 0.0 63.5 3.5 0.0 3.2 3.6 0.4 3.3 5.9 2.6 0.0 67.6 1.4 2.5 53.4 69.3 0.0 0.3 0.0 0.0 1.7 4.2 66.8 0.1 0.0 7.9 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.3 67.9 64.0 80.9 57.6 59.7 69.4 66.5 63.5 67.6 69.3 66.8 0.4 3.2 0.6 257.6 0.4 0.8 1.2 0.6 0.0 138.6 44.3 42.2 1.3 4.3 3.0 0.0 20.9 0.9 1.3 0.2 0.0 30.4 3.9 0.3 0.9 2.8 1.2 0.0 26.4 0.6 0.7 1.5 0.0 0.7 0.0 13.7 0.7 0.1 0.3 10.1 3.3 0.0 0.0 0.0 1.5 4.8 1.8 0.3 23.2 19.7 0.3 653.4 0.0 48.2 97.5 2.2 0.0 0.7 0.1 1.9 0.4 0.7 2.8 155.3 6.6 2.3 7.8 2.2 5.1 0.0 0.9 4.2 0.6 0.5 0.3 1.9 TULP3 TUBL3 ENSG00000078246 "TUB like protein 3" O75386 12 2877223-2941138 "Predicted intracellular proteins" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 70.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015285, HPA018496" Uncertain Supported "Nucleoplasm,Nucleoli,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA015285: AB_1858460, HPA018496: AB_2669889" "unprognostic (5.33e-2)" "unprognostic (1.57e-1)" "unprognostic (4.80e-2)" "prognostic favorable (2.99e-4)" "unprognostic (2.45e-1)" "unprognostic (1.78e-2)" "prognostic unfavorable (7.97e-5)" "unprognostic (2.44e-1)" "unprognostic (4.09e-2)" "unprognostic (1.73e-1)" "unprognostic (1.50e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (7.52e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-2)" "unprognostic (3.19e-2)" 21.0 17.1 13.6 7.5 14.2 2.6 18.3 19.2 16.1 33.3 15.8 21.6 5.4 23.2 11.7 17.8 24.3 12.1 17.7 13.8 13.2 17.3 9.0 13.5 6.1 16.3 14.8 37.7 9.6 13.3 12.3 13.7 13.8 15.4 8.2 12.7 13.0 13.9 10.4 25.7 10.5 18.2 14.5 9.4 15.5 13.0 14.4 9.4 15.5 9.7 8.1 16.7 24.1 17.1 22.6 18.8 35.0 29.1 34.3 51.0 32.9 34.5 57.5 36.4 40.2 24.0 20.4 16.7 5.1 51.2 31.2 18.5 21.1 22.2 42.0 21.7 15.4 10.0 23.4 15.5 44.3 10.8 11.1 30.1 25.7 55.3 74.9 44.6 28.6 20.8 9.7 15.1 31.0 20.3 16.1 9.4 47.4 17.8 13.7 16.8 34.2 6.3 22.9 18.7 8.8 23.4 30.1 17.8 19.9 63.4 22.2 10.5 23.0 26.6 32.0 54.7 33.9 4.7 6.0 14.3 26.9 5.9 41.5 0.0 0.9 0.3 2.1 0.8 3.5 1.6 1.7 2.2 0.7 1.8 2.0 2.8 0.4 2.7 0.5 1.6 3.3 1.0 13.6 14.2 19.2 16.1 13.8 13.2 16.3 14.8 13.8 14.5 14.4 17.1 12.9 6.4 10.5 70.5 6.2 20.3 16.9 14.8 26.2 6.1 9.9 12.2 8.0 18.6 15.9 1.8 2.1 9.4 6.0 4.6 23.5 17.3 5.8 35.1 33.5 15.2 3.6 6.1 6.0 7.3 10.6 31.7 6.6 14.6 0.0 11.5 24.3 5.5 5.3 40.4 10.8 4.0 14.2 2.5 8.6 3.6 40.7 5.4 19.6 14.0 6.7 50.7 12.3 10.1 34.9 11.1 2.4 24.8 8.3 23.3 3.2 21.9 47.4 10.0 39.5 22.3 26.3 38.0 50.8 22.2 20.2 11.6 6.5 13.3 6.4 13.2 TWF2 "A6r, A6RP, PTK9L" ENSG00000247596 "Twinfilin actin binding protein 2" Q6IBS0 3 52228612-52246788 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 183.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 205.0;monocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053874 Uncertain Uncertain "Plasma membrane" NA NA 5900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA053874: AB_2682287" "unprognostic (4.24e-2)" "unprognostic (8.61e-2)" "unprognostic (2.18e-1)" "unprognostic (2.62e-2)" "unprognostic (2.70e-2)" "unprognostic (3.51e-2)" "unprognostic (5.46e-3)" "unprognostic (2.76e-1)" "unprognostic (6.56e-2)" "unprognostic (1.97e-1)" "unprognostic (2.58e-2)" "unprognostic (5.07e-2)" "unprognostic (4.31e-3)" "unprognostic (4.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.07e-2)" 50.3 32.0 16.6 28.1 16.4 28.3 39.0 12.9 26.5 35.7 13.2 32.4 21.8 35.4 0.6 44.5 27.9 17.2 94.8 17.3 15.4 31.2 29.3 34.9 33.3 15.5 13.7 29.5 17.3 6.8 18.3 15.8 16.0 29.1 4.8 0.9 36.7 18.7 183.4 32.4 33.6 14.1 15.4 54.8 24.5 14.2 14.7 21.3 23.8 4.3 15.1 36.2 36.4 18.0 24.9 59.8 10.7 28.6 29.1 47.5 35.7 56.0 55.9 49.1 43.4 32.3 51.6 89.9 36.5 27.1 39.2 37.5 11.9 60.0 4.2 52.4 34.0 89.6 38.0 78.9 49.1 54.3 139.6 46.4 28.8 50.4 12.8 21.9 82.9 50.1 21.0 36.0 20.7 21.7 65.0 117.1 30.4 15.2 171.9 27.0 22.0 92.0 22.3 38.4 13.6 59.7 19.7 74.7 109.2 4.2 19.3 40.5 105.9 55.1 68.4 50.4 47.4 37.4 35.9 45.6 125.9 143.8 73.7 97.5 167.8 143.4 107.7 169.1 95.0 109.1 112.4 114.6 159.7 83.1 86.5 108.9 242.0 93.7 181.6 150.6 141.9 149.6 16.6 16.4 12.9 26.5 17.3 15.4 15.5 13.7 16.0 15.4 14.7 18.0 44.3 6.4 7.8 2.0 50.7 17.2 29.5 59.2 12.5 14.0 29.9 28.2 28.8 27.1 23.7 12.9 0.0 42.4 77.0 64.4 37.2 86.8 3.1 34.2 27.5 35.9 22.1 17.7 7.5 100.8 84.3 34.0 18.8 86.3 40.6 28.4 31.1 13.3 205.0 6.7 4.2 20.2 30.5 108.8 56.7 2.7 35.1 111.8 33.8 3.7 202.4 14.9 97.9 3.5 3.5 103.2 55.7 33.8 25.2 20.3 65.5 25.4 12.2 5.1 52.6 16.1 38.6 1.7 25.1 27.2 15.3 22.6 64.4 53.7 23.9 31.3 TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Plasma cells: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 141.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" 15.7 14.2 4.5 22.5 5.6 55.4 16.6 7.7 5.9 20.8 16.6 30.0 38.5 15.1 23.6 13.1 16.2 17.3 13.7 5.0 4.9 25.7 44.3 34.9 25.3 4.8 4.8 16.6 26.5 45.1 12.6 17.0 4.8 24.4 29.8 15.3 34.8 14.9 30.1 12.0 32.0 15.6 4.6 22.4 36.1 8.5 4.9 20.6 34.4 14.9 27.9 25.3 11.8 5.0 26.1 17.7 8.2 11.2 21.6 18.0 14.4 25.3 34.5 22.7 29.1 8.8 40.5 65.2 41.6 32.0 30.9 22.9 10.2 21.4 18.5 29.4 13.5 13.9 19.4 43.8 31.7 20.6 27.1 13.7 23.6 25.4 39.9 17.6 28.9 14.6 21.5 81.8 20.2 23.7 16.1 7.9 10.7 18.6 9.1 20.5 16.5 141.9 26.0 13.7 11.5 10.9 49.6 38.2 27.3 9.1 23.4 28.1 30.1 10.5 12.0 49.8 14.7 110.5 64.8 39.5 22.3 25.7 17.9 3.5 2.4 7.7 1.8 1.7 4.5 3.8 3.3 4.1 2.6 4.6 3.2 2.1 0.7 5.6 2.2 2.0 6.8 2.8 4.5 5.6 7.7 5.9 5.0 4.9 4.8 4.8 4.8 4.6 4.9 5.0 16.2 44.8 46.2 21.9 49.2 14.7 24.8 12.9 23.3 16.2 16.1 18.0 9.1 18.6 24.6 18.4 50.1 21.1 27.2 45.8 15.6 20.4 3.1 19.9 14.6 15.2 24.5 6.5 23.0 39.7 29.8 14.0 45.3 28.5 15.2 13.0 15.7 39.3 30.3 23.5 25.5 44.0 8.2 18.1 26.9 1.4 20.2 29.2 23.2 18.7 21.2 16.4 15.5 22.1 18.6 26.1 21.0 13.2 307.9 28.0 37.1 15.2 15.9 23.4 6.6 13.8 16.2 11.6 13.1 17.5 11.8 25.0 25.2 11.3 27.7 32.1 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2550.5;NK-cells: 2028.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 951.8;HSkMC: 1276.5;hTCEpi: 664.0;hTERT-RPE1: 781.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 1542.7 466.8 130.3 566.5 159.9 404.7 1396.7 137.1 158.5 846.0 133.8 965.4 223.3 811.8 381.2 428.7 730.3 395.0 745.2 120.3 136.6 532.6 204.0 841.9 800.8 182.0 144.9 382.9 580.5 634.0 192.3 594.0 185.4 352.4 487.5 14.5 567.0 554.5 1446.1 1060.4 810.7 658.7 157.1 946.4 713.4 106.4 159.2 373.7 556.6 2306.2 1068.8 740.9 638.7 217.3 56.5 0.2 13.0 0.9 291.6 951.8 29.7 66.0 131.3 58.5 79.7 35.3 74.6 15.8 379.6 18.1 9.7 15.0 13.0 124.8 154.8 74.2 7.1 45.7 20.2 32.6 13.8 189.7 91.7 1276.5 664.0 119.0 206.7 781.9 23.2 61.8 184.8 121.2 30.2 76.5 31.9 180.2 36.3 112.5 48.5 28.5 107.8 498.3 151.6 122.8 61.7 99.9 283.1 80.5 239.0 26.2 29.1 266.6 56.5 160.1 10.0 304.2 108.7 169.3 170.7 13.8 39.3 86.6 86.3 1059.6 571.2 1219.2 792.2 551.3 729.8 519.3 668.8 710.4 334.4 542.4 650.2 708.5 1246.6 637.1 496.3 154.8 674.5 1684.4 130.3 159.9 137.1 158.5 120.3 136.6 182.0 144.9 185.4 157.1 159.2 217.3 2550.5 227.6 328.5 26.4 1360.4 70.7 236.9 129.8 413.8 6.5 167.4 111.2 526.0 185.8 184.4 272.2 29.2 5.0 1004.6 578.0 450.0 79.7 8.3 179.8 594.5 740.2 164.2 270.8 0.2 53.8 4.1 666.5 160.5 464.2 377.4 53.6 349.8 114.8 231.9 6.7 0.5 320.9 136.3 845.1 184.9 35.5 654.5 730.8 108.5 36.5 892.0 3.6 2028.9 45.2 55.8 225.7 459.4 447.2 639.6 370.7 79.0 169.3 155.8 3.7 1196.5 452.4 398.7 7.6 63.7 160.1 72.2 10.9 1142.8 303.9 186.9 516.2 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029641 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA029641: AB_2272535" "unprognostic (6.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (7.24e-2)" "prognostic unfavorable (1.49e-7)" "unprognostic (3.79e-1)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-2)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" "unprognostic (8.90e-2)" "unprognostic (2.98e-3)" 12.9 15.4 10.8 11.7 11.8 13.1 17.0 11.3 12.7 13.4 10.2 15.2 8.9 16.0 12.2 11.6 14.7 9.2 20.3 10.5 12.5 17.4 13.8 10.6 14.6 11.2 12.1 26.6 11.7 21.5 11.7 12.7 11.8 15.1 11.1 14.6 14.0 13.6 10.6 9.9 8.9 17.9 11.5 11.0 11.5 11.9 11.6 12.7 19.2 14.4 16.4 15.2 11.1 13.2 19.6 16.1 27.3 19.5 30.3 32.9 41.4 32.9 30.0 30.7 26.9 34.3 16.2 51.0 29.4 28.6 45.1 15.6 31.5 37.9 38.3 31.9 27.1 40.2 49.4 67.0 19.9 81.2 24.9 25.1 37.7 39.2 37.6 24.7 27.7 34.8 70.8 38.0 39.9 16.6 39.8 27.1 72.8 29.2 37.2 37.2 56.8 23.0 26.6 25.2 21.1 18.0 15.7 42.4 53.7 29.5 23.2 29.3 18.2 13.6 37.0 37.0 40.2 21.9 42.7 35.4 30.3 29.0 39.9 9.1 6.4 1.8 10.6 8.8 10.0 10.7 9.2 9.7 9.9 9.8 13.2 14.2 0.5 15.4 6.9 9.6 9.4 5.8 10.8 11.8 11.3 12.7 10.5 12.5 11.2 12.1 11.8 11.5 11.6 13.2 30.6 16.0 23.9 17.6 34.1 25.6 40.5 32.7 58.1 34.5 32.4 42.3 29.9 20.0 28.6 16.5 4.2 44.5 21.2 7.4 78.2 36.2 19.8 28.9 38.8 31.7 13.8 18.5 28.0 59.4 51.1 34.7 15.8 29.0 21.0 32.8 21.8 29.2 33.1 50.5 22.7 19.5 22.4 30.9 22.6 19.6 43.5 26.2 21.4 14.0 39.5 27.6 37.0 30.2 24.5 32.5 8.4 61.3 35.6 45.7 12.2 64.4 18.4 22.5 13.1 44.2 36.0 34.3 45.3 44.1 22.7 22.3 29.2 55.7 25.9 31.2 UAP1 "AgX, AGX1, SPAG2" ENSG00000117143 "UDP-N-acetylglucosamine pyrophosphorylase 1" Q16222 1 162561506-162599842 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 678.4;U-251 MG: 463.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014659 Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" No Yes 48000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane, Cytosol" "HPA014659: AB_1857409" "unprognostic (2.32e-2)" "unprognostic (2.45e-1)" "unprognostic (2.07e-2)" "unprognostic (1.28e-2)" "unprognostic (2.71e-2)" "unprognostic (1.46e-2)" "unprognostic (1.37e-2)" "unprognostic (1.47e-1)" "unprognostic (2.09e-1)" "unprognostic (1.30e-1)" "unprognostic (1.29e-3)" "unprognostic (4.96e-2)" "prognostic unfavorable (5.12e-5)" "unprognostic (1.59e-1)" "unprognostic (2.04e-1)" "unprognostic (3.51e-1)" "unprognostic (3.45e-2)" 96.0 43.7 12.2 33.7 13.2 51.5 58.8 13.5 14.9 37.1 16.1 65.6 43.9 18.6 29.1 33.9 33.1 39.8 45.1 13.4 13.6 27.0 172.6 36.0 14.1 11.5 16.9 39.9 68.6 12.0 28.9 22.3 11.8 33.3 66.3 20.4 76.6 31.2 41.2 25.0 56.0 24.6 11.6 13.8 55.8 90.9 13.9 11.8 24.4 45.2 22.2 77.9 37.4 11.0 204.6 14.6 39.2 31.5 185.7 147.8 26.8 292.4 107.1 220.7 178.5 38.6 93.5 8.0 64.3 225.8 79.6 35.0 44.7 85.5 359.9 32.4 66.6 36.0 43.8 75.6 87.1 61.8 23.5 69.0 39.8 242.4 678.4 100.6 137.5 62.6 206.1 81.3 298.9 37.4 36.0 40.0 29.2 207.6 64.4 31.9 76.2 99.8 34.8 23.7 41.9 43.4 128.0 78.4 70.4 45.6 38.9 70.0 235.2 110.6 102.5 281.2 463.5 135.0 51.0 67.0 63.4 28.5 71.3 1.4 2.2 11.7 16.7 2.1 20.4 10.7 10.0 17.3 4.6 11.1 9.4 12.0 2.2 8.6 1.2 7.7 5.5 7.2 12.2 13.2 13.5 14.9 13.4 13.6 11.5 16.9 11.8 11.6 13.9 11.0 58.1 6.4 30.2 15.0 42.5 134.7 163.0 47.2 47.8 11.8 59.1 42.7 30.0 27.1 57.4 16.5 8.4 27.2 82.9 94.8 72.4 27.1 78.2 28.6 58.0 35.7 54.9 13.9 12.4 64.7 63.9 195.8 45.9 40.7 33.7 21.3 22.5 98.4 14.5 6.7 12.4 139.4 40.7 10.1 82.2 20.1 50.7 24.6 85.4 3.7 18.2 16.6 41.2 8.0 6.1 73.0 74.5 41.3 152.8 94.6 88.4 26.9 56.0 13.9 19.7 59.4 88.6 212.0 125.9 43.2 81.8 97.7 50.5 18.8 70.4 141.7 UBA3 "hUba3, NAE2, UBE1C" ENSG00000144744 "Ubiquitin like modifier activating enzyme 3" Q8TBC4 3 69054730-69080408 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Ubl conjugation pathway" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "brain: 383.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034873, HPA034874, HPA065335" Supported Approved "Nucleoplasm,Plasma membrane,Centrosome,Cytosol" NA NA 35000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "Nucleoplasm, Centrosome" "HPA034873: AB_10670578, HPA034874: AB_2674368, HPA065335: AB_2685473" "unprognostic (2.31e-1)" "unprognostic (1.75e-1)" "unprognostic (5.56e-3)" "unprognostic (9.26e-2)" "unprognostic (9.35e-3)" "unprognostic (5.53e-2)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.08e-1)" "unprognostic (6.18e-2)" "unprognostic (1.60e-3)" "unprognostic (9.40e-2)" "unprognostic (2.71e-2)" "unprognostic (1.39e-3)" "unprognostic (2.61e-3)" "unprognostic (9.24e-2)" "unprognostic (7.80e-3)" "unprognostic (2.52e-1)" 34.3 32.3 83.7 39.4 225.9 39.1 43.4 138.0 136.2 32.1 32.1 34.5 28.8 35.8 41.0 33.9 27.5 29.7 66.6 109.7 198.7 33.9 31.2 32.2 49.6 240.4 162.7 30.0 19.3 45.6 22.9 41.7 245.4 36.6 35.8 62.0 44.9 32.2 41.5 45.0 30.3 39.8 131.0 38.9 26.4 23.7 197.1 44.8 27.1 34.7 49.8 39.4 26.6 383.0 76.6 31.4 75.8 47.1 69.0 90.9 56.1 65.9 74.4 70.4 70.2 39.2 52.2 55.2 18.6 72.5 71.3 42.1 59.1 76.5 80.2 105.0 38.5 77.0 57.7 39.6 53.8 77.1 62.4 72.0 49.8 67.9 54.9 86.7 92.3 45.2 31.9 45.6 94.0 26.8 49.5 49.7 67.5 95.4 26.9 39.6 55.9 53.0 113.2 94.6 32.8 46.2 70.3 51.0 58.4 80.9 34.3 73.3 71.4 53.0 46.9 70.6 93.3 53.2 91.8 67.3 54.5 84.3 69.7 87.9 45.7 71.0 24.3 54.0 28.1 33.6 32.2 30.3 40.1 29.7 29.6 30.5 40.9 39.8 57.1 20.1 40.8 53.0 83.7 225.9 138.0 136.2 109.7 198.7 240.4 162.7 245.4 131.0 197.1 383.0 21.9 35.3 31.4 35.9 35.5 33.8 29.2 66.2 31.9 22.9 21.6 17.9 68.5 14.3 44.5 35.0 39.6 74.5 19.8 15.8 19.6 37.1 15.2 25.1 21.2 26.9 18.6 30.7 44.6 23.6 57.2 28.3 22.4 25.6 42.4 26.0 22.9 17.2 34.1 33.7 62.8 16.3 97.6 37.1 49.6 10.3 40.4 39.6 30.2 44.0 60.6 29.1 24.7 53.3 76.7 31.5 11.7 38.0 28.3 23.7 16.7 36.9 47.3 48.9 26.3 22.2 31.0 34.2 32.1 34.9 42.8 56.8 34.0 24.3 17.5 32.5 UBA52 "CEP52, HUBCEP52, L40, MGC126879, MGC126881, MGC57125, RPL40" ENSG00000221983 "Ubiquitin A-52 residue ribosomal protein fusion product 1" P62987 19 18571730-18577550 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 11928.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041344, HPA049132, HPA056624" Supported Approved "Nucleoplasm,Endoplasmic reticulum,Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Endoplasmic reticulum, Cytosol" "Nucleoplasm, Plasma membrane" "HPA041344: AB_2677422, HPA049132: AB_2680646, HPA056624: AB_2683196" "unprognostic (1.98e-2)" "unprognostic (9.35e-2)" "unprognostic (1.46e-1)" "unprognostic (4.72e-2)" "unprognostic (5.36e-3)" "unprognostic (9.35e-2)" "unprognostic (1.74e-3)" "unprognostic (4.00e-2)" "unprognostic (7.44e-2)" "unprognostic (1.72e-1)" "unprognostic (1.27e-1)" "unprognostic (2.87e-1)" "unprognostic (2.52e-3)" "unprognostic (1.87e-1)" "unprognostic (5.61e-2)" "unprognostic (2.43e-1)" "unprognostic (2.23e-1)" 1161.5 955.0 823.8 793.2 845.7 2181.5 1115.4 815.0 1021.1 1262.7 808.6 984.4 531.1 938.2 966.2 1196.8 984.5 610.9 989.3 803.8 848.5 931.1 927.4 888.7 1469.5 861.9 825.6 1622.0 1664.8 844.0 758.0 720.8 858.2 917.0 789.6 235.6 1061.1 615.4 1629.9 1444.0 916.6 712.9 883.0 1239.2 989.5 755.3 853.4 1487.1 748.6 1196.7 1674.0 995.3 1107.5 875.5 1680.6 1304.1 961.2 1612.8 2437.7 2298.9 2376.3 1260.7 1738.5 2044.2 1618.9 2381.2 1521.6 2403.4 1268.0 2092.8 803.0 1103.3 1881.9 2242.7 1918.7 650.0 2938.0 1320.1 1942.1 2733.4 1770.8 2898.3 1616.2 2684.2 3008.4 1406.4 2024.7 1778.7 2083.2 1508.8 2131.5 3231.7 1769.8 2786.9 2336.4 2584.2 2162.6 3166.1 2800.9 1899.3 958.6 2769.6 2001.7 2497.0 1246.1 1505.9 914.3 2187.0 2300.9 1424.6 970.6 3681.4 1562.7 1017.6 850.0 2172.8 2271.9 1973.0 2863.7 2412.2 1386.0 3245.8 1412.8 962.6 2155.2 1163.1 1761.2 1764.2 2401.7 3126.7 2616.4 2119.8 2320.3 3025.4 2946.4 2445.0 1168.8 1864.5 1629.2 2469.2 2250.9 4829.5 823.8 845.7 815.0 1021.1 803.8 848.5 861.9 825.6 858.2 883.0 853.4 875.5 831.5 464.8 673.1 15.0 2198.0 1898.4 2027.9 1544.8 1365.8 117.9 1444.5 1279.9 332.3 1109.5 886.1 654.7 68.8 2020.5 1806.7 1264.6 1571.0 1437.7 3146.5 772.1 1337.9 1108.6 1106.6 2241.7 10.8 2271.5 2803.3 1060.1 672.2 1194.9 805.8 1061.9 1385.3 1919.9 2574.7 104.3 12.4 1812.7 710.1 3200.4 2894.6 11928.8 1875.2 2003.3 1250.4 8.4 3379.8 599.1 2276.1 11.1 23.1 1799.4 1853.6 1034.7 1202.4 2110.3 1645.1 2688.2 510.4 219.1 696.8 1483.1 2041.1 629.9 674.5 1939.2 2239.4 2282.9 1892.0 1285.6 1783.6 2426.6 UBAC1 "GBDR1, KPC2, UBADC1" ENSG00000130560 "UBA domain containing 1" Q9BSL1 9 135932969-135961373 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 301.3;tongue: 171.0" "Cell type enhanced" "Detected in all" "Erythroid cells: 290.9;Late spermatids: 197.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 246.4;K-562: 316.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005651 Approved Supported "Golgi apparatus,Plasma membrane,Cytosol" NA NA 87000 "Cluster 14: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "Golgi apparatus" "HPA005651: AB_1858489" "unprognostic (8.41e-2)" "prognostic favorable (4.34e-6)" "unprognostic (2.10e-1)" "unprognostic (9.15e-2)" "unprognostic (4.11e-1)" "unprognostic (3.85e-2)" "unprognostic (7.68e-3)" "unprognostic (2.85e-1)" "unprognostic (4.37e-2)" "unprognostic (3.23e-1)" "unprognostic (3.92e-3)" "unprognostic (1.20e-1)" "prognostic favorable (3.58e-7)" "unprognostic (1.95e-3)" "unprognostic (9.46e-2)" "unprognostic (3.16e-2)" "unprognostic (5.78e-2)" 23.1 20.7 42.2 14.7 44.8 82.5 20.7 43.0 43.0 23.8 41.4 38.6 24.3 22.0 12.9 37.4 22.8 12.0 72.0 40.4 42.2 23.5 24.9 19.8 15.7 43.2 42.7 20.9 17.1 27.1 23.5 22.8 41.8 24.7 18.4 15.2 27.8 20.6 301.3 53.2 23.3 16.3 43.7 21.0 23.0 43.1 44.0 17.7 18.0 171.0 16.5 28.3 27.0 41.0 37.4 42.7 29.7 43.4 22.0 25.6 55.7 32.0 27.1 38.9 31.2 59.7 46.3 44.8 30.1 26.4 46.1 124.4 41.9 37.0 17.5 246.4 39.6 37.4 79.0 33.8 22.9 49.2 34.4 24.2 47.7 24.6 23.8 26.0 32.8 41.4 316.6 35.5 31.2 76.9 40.4 50.5 70.5 87.4 71.8 45.1 55.8 59.3 28.0 23.7 46.0 50.6 46.3 41.4 33.5 26.3 34.9 52.5 26.8 22.0 33.0 26.5 40.2 20.5 41.1 53.9 40.7 43.9 30.6 6.5 17.6 8.7 4.8 28.4 5.1 4.9 5.4 3.2 15.6 2.8 2.8 3.3 3.7 4.0 33.4 1.6 4.5 7.0 42.2 44.8 43.0 43.0 40.4 42.2 43.2 42.7 41.8 43.7 44.0 41.0 42.8 16.0 10.0 18.6 14.5 40.7 38.8 41.8 43.3 38.3 29.6 36.2 85.7 11.5 24.5 27.6 31.3 148.6 20.7 45.5 93.9 16.3 101.6 82.9 33.7 27.5 16.8 290.9 17.3 22.9 32.7 22.5 21.9 21.3 7.0 28.6 20.3 32.7 75.2 13.5 23.6 37.4 28.5 34.3 30.3 197.4 19.6 41.8 35.6 9.4 46.0 60.7 13.4 9.0 14.1 22.6 42.3 22.6 24.6 23.1 47.9 35.6 96.0 44.1 19.7 42.8 27.4 57.7 54.9 73.2 64.8 60.5 16.5 25.7 55.6 39.4 UBALD1 FAM100A ENSG00000153443 "UBA like domain containing 1" Q8TB05 16 4608883-4615027 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 110.3;Late spermatids: 129.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 8.7" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA066771 Approved Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Cytosol" "Cell Junctions" "HPA066771: AB_2685717" "unprognostic (7.09e-2)" "unprognostic (2.21e-2)" "unprognostic (1.55e-1)" "unprognostic (7.67e-3)" "unprognostic (1.27e-1)" "unprognostic (1.37e-1)" "unprognostic (1.31e-1)" "unprognostic (1.72e-1)" "unprognostic (2.54e-1)" "unprognostic (4.37e-3)" "unprognostic (2.63e-3)" "unprognostic (8.06e-2)" "unprognostic (1.95e-3)" "unprognostic (2.35e-1)" "unprognostic (3.99e-2)" "unprognostic (6.20e-2)" "unprognostic (1.35e-2)" 25.5 28.4 21.7 11.1 20.0 26.2 24.6 23.9 39.5 29.9 7.4 44.3 14.2 38.6 2.6 32.8 32.0 6.2 39.8 23.3 16.4 39.2 70.6 29.9 8.7 16.2 14.2 29.2 30.1 5.1 25.0 10.6 14.5 39.6 2.3 4.8 23.7 9.5 51.1 31.4 25.5 6.8 10.6 29.3 34.9 29.1 16.8 5.5 35.4 8.6 4.4 33.5 27.5 24.2 13.5 38.2 8.9 14.2 6.0 7.6 39.4 19.7 8.2 7.6 11.0 18.6 15.5 19.8 21.6 6.3 5.7 36.5 5.7 20.4 2.1 42.4 57.4 18.7 42.8 29.6 12.1 11.8 30.8 10.8 14.9 11.6 5.7 8.7 8.3 15.0 28.7 20.4 3.0 66.0 19.5 63.6 33.3 12.0 33.4 27.9 11.1 65.6 6.7 19.0 25.7 23.7 23.5 35.9 33.1 5.1 23.2 18.9 24.4 15.2 17.2 61.5 13.0 38.8 34.2 22.9 6.2 15.8 8.1 0.9 1.6 8.7 1.6 2.5 1.0 1.3 1.3 1.7 1.9 1.2 1.3 1.4 2.7 1.1 3.3 1.2 1.7 1.3 21.7 20.0 23.9 39.5 23.3 16.4 16.2 14.2 14.5 10.6 16.8 24.2 12.0 9.6 8.2 3.3 14.3 110.3 55.8 32.7 29.6 9.7 23.7 20.6 4.2 15.7 17.9 18.4 4.2 65.8 15.1 26.4 31.3 21.1 37.6 29.1 16.2 16.8 84.6 26.1 6.2 23.6 60.1 16.2 43.3 28.7 10.8 13.6 16.1 32.4 23.6 10.1 6.1 34.4 28.5 14.7 25.9 129.1 16.1 14.5 21.4 1.9 19.4 13.0 23.7 3.5 8.1 22.4 19.0 19.9 22.2 37.6 24.4 57.0 7.3 11.5 46.0 15.2 25.1 18.6 14.6 20.2 102.9 107.8 15.9 14.0 22.0 33.1 UBAP1 UBAP ENSG00000165006 "Ubiquitin associated protein 1" Q9NZ09 9 34179005-34252523 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019804 Approved Supported "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" Cytosol "Vesicles, Plasma membrane" "HPA019804: AB_1858494" "unprognostic (1.83e-1)" "unprognostic (4.30e-2)" "unprognostic (1.29e-1)" "unprognostic (1.70e-1)" "unprognostic (3.54e-1)" "unprognostic (3.29e-2)" "unprognostic (1.67e-1)" "unprognostic (1.59e-1)" "unprognostic (2.01e-2)" "unprognostic (6.53e-2)" "unprognostic (1.25e-2)" "unprognostic (3.63e-1)" "prognostic favorable (7.49e-6)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.46e-1)" "unprognostic (1.17e-1)" 40.7 55.5 46.4 24.5 47.1 131.5 35.8 48.0 53.4 45.0 46.4 38.5 22.3 34.0 25.5 69.7 33.9 30.4 38.2 45.6 48.2 34.8 53.1 42.5 23.8 48.5 48.5 40.9 28.0 34.4 25.6 29.3 49.4 30.4 24.8 44.8 29.6 30.6 110.0 39.5 26.3 35.2 46.3 28.2 33.6 47.8 49.9 31.6 25.6 71.7 32.7 38.0 45.8 48.2 56.7 31.7 35.2 38.4 63.6 39.3 29.8 44.4 61.6 48.4 65.6 34.3 23.0 39.3 19.5 66.5 41.1 28.3 49.2 69.5 46.4 57.1 22.3 35.1 65.4 35.5 57.8 39.3 44.8 48.7 113.0 57.5 75.0 73.4 54.4 37.9 27.4 38.0 45.7 23.7 36.5 55.0 38.2 38.8 45.9 32.6 24.8 22.8 104.2 36.9 19.9 28.1 49.0 50.2 22.5 31.1 24.6 38.5 39.2 24.7 38.0 37.4 41.5 18.9 25.3 41.0 49.5 31.5 74.2 26.8 50.9 66.6 38.0 45.2 65.8 26.8 38.1 40.0 47.1 23.2 36.3 29.8 120.2 50.1 41.0 26.7 52.9 55.0 46.4 47.1 48.0 53.4 45.6 48.2 48.5 48.5 49.4 46.3 49.9 48.2 21.6 67.3 26.0 44.4 22.4 46.9 66.3 20.4 45.5 15.8 27.9 23.1 13.1 20.0 33.5 7.3 25.0 33.2 21.6 25.8 19.6 34.8 77.5 56.9 37.2 21.4 16.1 50.7 33.1 40.1 35.4 31.2 44.4 90.0 25.9 15.4 17.5 25.3 22.0 6.7 42.9 18.5 30.5 21.4 39.8 62.9 29.2 38.2 24.9 26.2 23.1 26.0 13.4 38.7 35.4 44.3 23.0 42.5 25.0 47.9 22.5 21.0 22.5 10.9 19.7 44.0 32.5 51.0 22.9 54.6 59.0 89.6 28.6 20.8 18.8 70.9 UBE2A "HHR6A, HR6A, RAD6A, UBC2" ENSG00000077721 "Ubiquitin conjugating enzyme E2 A" P49459 X 119574536-119591083 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Chromatin regulator, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 508.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (2.27e-3)" "prognostic favorable (2.16e-4)" "unprognostic (1.12e-1)" "unprognostic (9.09e-2)" "unprognostic (1.63e-1)" "prognostic unfavorable (9.07e-4)" "unprognostic (1.66e-3)" "unprognostic (1.96e-2)" "unprognostic (6.54e-2)" "unprognostic (2.96e-2)" "unprognostic (3.49e-2)" "unprognostic (1.33e-1)" "prognostic unfavorable (2.20e-6)" "unprognostic (9.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.21e-1)" "unprognostic (7.92e-2)" 40.0 27.4 30.1 39.1 30.6 29.8 29.4 34.1 38.8 34.1 27.1 52.3 37.5 32.0 38.2 53.4 27.3 32.6 63.2 29.6 32.2 41.0 30.1 32.9 46.9 34.4 32.5 20.1 29.2 39.2 18.9 56.8 34.4 31.0 45.0 27.1 30.9 33.0 71.9 30.7 39.1 43.0 32.1 26.8 30.5 17.6 32.1 46.1 30.5 55.0 50.4 46.9 32.8 35.1 129.5 104.1 60.8 54.1 103.0 125.6 63.9 122.6 106.3 141.8 130.3 50.8 84.0 96.4 126.4 133.9 240.6 86.4 86.3 65.7 128.6 142.3 60.6 42.7 71.9 47.1 96.6 105.9 72.1 86.9 90.1 134.0 58.3 98.1 99.4 86.5 57.0 83.6 160.1 134.5 166.6 99.9 106.3 125.7 126.9 84.2 64.0 91.6 113.1 76.6 48.9 51.3 171.2 75.0 93.7 73.2 65.8 92.6 101.5 92.4 42.0 184.3 142.5 83.6 147.1 92.4 99.1 136.3 74.6 46.8 58.5 92.5 43.0 92.1 34.8 52.6 37.9 38.5 74.6 48.7 23.7 33.9 78.0 35.0 101.1 58.5 56.8 51.1 30.1 30.6 34.1 38.8 29.6 32.2 34.4 32.5 34.4 32.1 32.1 35.1 67.5 102.5 40.9 12.7 79.1 124.8 91.6 129.4 51.8 17.2 60.7 43.9 66.7 44.3 80.7 40.5 31.3 179.8 93.0 168.6 101.8 95.4 51.7 75.6 55.3 62.9 45.5 70.4 9.9 102.1 176.2 67.7 37.8 63.0 57.0 35.7 46.4 35.5 131.3 8.4 9.4 49.7 103.7 59.1 183.9 15.3 37.0 97.3 83.6 15.9 129.0 49.8 41.2 14.6 18.0 137.6 132.5 40.6 92.2 98.2 85.6 125.2 107.7 35.0 46.0 56.3 101.1 44.1 32.1 74.6 127.9 508.5 94.8 36.6 54.5 120.3 UBE2B "HHR6B, RAD6B, UBC2" ENSG00000119048 "Ubiquitin conjugating enzyme E2 B" P63146 5 134371469-134392108 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 265.8" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 723.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 444.6" "Lineage enriched" "Detected in all" 6 "granulocytes: 444.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003875, HPA051765, HPA065898" Supported "Nucleoplasm,Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Nucleoplasm, Plasma membrane" "Vesicles, Cytosol" "HPA003875: AB_2667061, HPA051765: AB_2681597, HPA065898: AB_2685577" "unprognostic (1.98e-1)" "unprognostic (1.35e-1)" "unprognostic (7.39e-2)" "unprognostic (6.66e-2)" "unprognostic (1.44e-1)" "unprognostic (1.48e-2)" "unprognostic (2.56e-1)" "unprognostic (1.27e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-1)" "unprognostic (2.49e-1)" "unprognostic (8.39e-2)" "unprognostic (1.64e-3)" "unprognostic (6.30e-3)" "unprognostic (3.42e-2)" "unprognostic (2.04e-1)" "unprognostic (5.52e-2)" 52.5 74.2 31.5 50.0 33.1 84.4 44.2 36.3 53.2 38.3 30.2 48.0 40.7 53.6 34.8 70.5 37.3 51.0 118.4 34.3 34.8 50.6 56.6 44.9 47.1 29.5 31.0 44.4 53.7 25.8 39.9 48.4 31.0 32.9 42.0 29.2 39.7 23.2 265.8 43.1 46.4 43.3 30.3 43.7 39.6 49.2 32.9 29.3 41.2 99.8 48.1 42.8 43.2 36.7 109.4 27.9 58.2 55.0 50.0 54.1 92.7 80.2 43.5 51.4 60.9 85.6 70.9 58.7 94.1 52.3 138.7 42.7 45.8 60.4 56.0 94.5 47.6 32.1 75.9 92.8 58.2 38.8 63.7 46.5 80.2 47.4 39.3 68.1 44.1 48.8 61.1 103.5 46.8 63.4 62.5 102.1 24.9 32.6 26.7 61.6 63.8 83.8 46.6 82.9 77.6 60.1 62.9 29.3 147.9 62.5 63.0 106.0 87.6 57.8 40.8 78.9 89.4 86.1 129.4 87.0 65.2 72.8 59.4 236.7 58.3 174.0 46.9 68.3 42.9 49.7 58.8 48.1 42.6 47.9 69.9 60.6 444.6 53.0 78.9 48.0 77.5 64.1 31.5 33.1 36.3 53.2 34.3 34.8 29.5 31.0 31.0 30.3 32.9 36.7 187.5 73.7 61.6 40.1 176.5 364.7 321.2 215.1 175.8 77.8 169.9 156.5 315.8 147.3 113.7 75.4 81.3 144.5 182.0 183.1 172.1 173.8 233.2 139.8 102.2 149.7 131.8 261.2 103.0 169.5 123.0 183.3 113.2 167.8 116.8 81.7 115.3 97.4 119.4 87.5 84.2 141.0 181.0 131.5 323.9 315.4 155.0 184.2 227.7 49.6 190.6 150.0 113.3 44.7 68.4 210.6 195.2 113.2 162.5 343.9 153.4 170.7 111.7 91.3 151.2 154.9 262.9 223.5 201.7 145.5 369.7 723.5 192.0 140.4 105.7 488.1 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.7;tongue: 65.3" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 194.4;Suprabasal keratinocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 13.0 11.8 5.3 16.7 5.7 32.4 7.8 6.6 8.1 8.9 4.4 11.4 7.0 12.6 7.5 11.6 7.1 9.5 33.3 6.1 6.2 8.1 8.3 8.9 13.8 6.6 6.4 8.4 5.5 8.9 3.9 8.9 6.6 9.5 12.0 5.4 5.5 6.7 138.7 5.9 8.3 13.6 6.4 13.4 6.4 4.5 6.3 7.8 8.4 65.3 11.4 15.1 5.6 6.7 19.1 10.2 18.8 24.4 37.5 30.0 12.1 12.4 21.2 13.9 20.3 20.9 16.4 0.0 19.0 18.6 10.3 17.1 36.6 18.0 19.5 19.8 21.2 4.9 3.7 12.2 24.4 15.3 11.8 34.8 19.9 14.4 26.8 18.7 28.1 13.1 10.0 7.8 19.1 6.1 16.5 17.1 23.0 11.7 15.7 13.8 16.9 10.6 21.2 11.2 14.0 18.8 24.2 40.3 20.6 28.5 14.8 10.2 22.8 5.3 18.6 18.2 13.7 19.7 16.4 16.8 16.7 31.3 6.2 10.1 38.5 17.8 6.2 27.1 7.2 8.9 7.3 7.9 20.0 9.8 7.5 6.2 112.3 8.2 23.4 8.3 9.8 23.4 5.3 5.7 6.6 8.1 6.1 6.2 6.6 6.4 6.6 6.4 6.3 6.7 41.6 12.8 11.2 5.5 54.3 194.4 94.1 60.6 46.1 23.7 45.6 45.5 92.4 17.2 39.0 27.6 18.8 29.9 41.7 27.4 76.3 62.3 5.0 32.6 46.9 42.5 41.7 12.0 18.5 42.0 50.4 51.9 38.7 51.2 22.9 19.6 27.5 15.6 73.7 16.8 17.1 40.1 69.2 90.6 104.0 3.0 33.2 147.7 53.4 4.7 94.6 17.9 22.6 12.5 21.2 81.2 52.7 32.4 26.4 108.4 16.1 54.3 33.6 16.1 6.6 51.4 59.1 33.5 19.9 47.1 190.2 149.0 42.8 14.9 28.5 118.2 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628434 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favorable (5.09e-5)" "prognostic favorable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 78.4 59.9 75.8 66.9 82.0 106.9 72.6 79.3 84.2 84.2 63.0 106.8 46.5 72.8 102.6 89.0 95.0 49.8 93.7 77.9 85.8 80.1 82.6 77.0 83.5 78.7 80.4 64.3 66.5 72.8 62.3 65.5 80.0 57.0 92.8 77.2 61.0 72.3 190.3 77.9 70.4 74.3 81.9 79.3 70.2 135.6 80.1 128.0 61.3 127.3 140.2 79.7 72.8 86.4 175.9 113.9 194.3 137.0 127.9 161.7 125.4 179.6 165.5 204.7 238.6 292.0 160.6 247.8 229.1 185.7 254.0 108.8 192.6 300.2 272.5 162.4 113.7 140.1 115.0 172.1 249.9 136.9 119.7 129.9 152.0 204.9 301.8 177.4 221.8 159.5 125.0 203.1 192.9 175.5 215.3 197.2 108.1 60.4 124.0 162.7 198.1 179.6 220.4 202.0 177.5 117.0 157.1 198.7 309.4 413.4 125.2 121.6 148.9 156.4 87.6 132.5 223.5 146.0 260.0 343.8 112.3 223.2 128.0 44.1 57.0 115.9 57.7 53.7 62.1 89.2 82.1 80.9 63.3 90.7 102.5 90.3 90.7 65.1 66.2 106.1 110.8 58.0 75.8 82.0 79.3 84.2 77.9 85.8 78.7 80.4 80.0 81.9 80.1 86.4 137.1 32.1 69.8 35.9 215.4 171.8 182.3 204.8 112.7 76.3 124.8 146.9 96.4 124.4 96.5 68.0 81.3 181.4 205.8 158.0 215.2 208.4 637.0 457.2 94.2 131.0 123.4 148.8 62.0 178.4 228.0 104.8 77.5 230.9 138.8 119.4 109.9 80.6 178.0 94.2 54.4 120.8 142.4 136.4 203.4 550.0 104.4 150.8 152.9 49.6 189.5 170.7 234.8 38.2 65.7 228.7 127.1 93.6 237.3 234.8 123.8 200.9 63.9 105.1 118.3 102.2 171.2 459.7 152.5 149.4 203.7 249.6 217.1 111.7 160.4 247.1 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 182.7 171.7 85.7 172.0 92.6 478.3 141.9 101.1 120.6 127.1 93.4 154.9 154.0 125.3 113.8 173.4 125.9 142.5 149.4 92.1 103.9 172.2 251.4 175.3 189.6 102.5 96.0 131.5 154.2 133.5 98.4 159.0 99.8 106.8 144.4 129.0 116.7 102.1 243.6 136.4 158.3 129.9 101.4 149.5 144.4 127.0 95.6 198.5 159.2 197.9 197.0 185.6 128.0 113.7 301.6 169.1 275.4 223.4 286.2 408.0 235.9 301.2 395.1 260.1 243.6 257.4 416.4 319.3 190.6 304.4 336.8 168.6 294.7 400.8 352.5 299.6 149.8 292.0 165.8 209.6 300.3 415.5 240.4 314.0 247.9 288.6 398.9 334.3 343.4 258.7 372.9 316.4 350.9 243.1 613.4 235.1 200.2 341.0 167.1 318.4 269.9 231.5 261.5 283.7 275.6 232.1 183.5 464.8 349.6 318.2 193.0 241.0 318.4 270.0 231.1 179.2 276.3 277.9 389.8 491.3 288.2 227.2 297.0 614.9 253.7 394.0 163.5 256.0 216.3 165.9 203.4 194.4 217.6 139.2 205.8 190.5 817.2 215.7 271.9 149.8 229.6 422.1 85.7 92.6 101.1 120.6 92.1 103.9 102.5 96.0 99.8 101.4 95.6 113.7 303.4 166.7 193.1 98.9 291.7 844.0 693.9 408.2 233.9 133.7 251.5 166.9 229.8 193.0 242.3 139.8 125.1 311.5 317.4 336.1 547.8 361.0 779.4 257.1 246.7 344.0 240.8 348.7 159.7 382.2 561.6 286.0 202.3 371.3 224.9 154.8 193.1 235.7 392.9 122.8 145.8 283.8 303.2 403.0 825.6 635.1 164.7 415.1 357.5 111.5 399.4 160.0 280.2 104.5 185.0 454.4 347.2 149.0 296.4 612.3 335.8 428.8 242.4 170.6 105.2 270.6 531.9 217.2 180.7 258.2 813.3 638.4 382.5 172.3 268.2 784.3 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926436-43956136 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 32.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 30.2" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favorable (4.86e-4)" "prognostic favorable (5.77e-4)" "prognostic favorable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 5.8 8.3 11.7 2.4 12.2 2.2 5.0 14.2 17.6 4.6 9.8 6.5 2.4 4.5 5.7 5.2 4.5 3.4 10.9 12.3 11.2 6.9 10.7 4.4 2.7 12.0 11.7 5.1 10.0 4.6 5.1 2.8 11.9 5.7 2.9 6.9 5.6 4.4 32.5 4.9 3.9 4.4 11.8 4.7 4.6 3.0 11.5 2.7 4.9 27.8 2.7 5.3 5.2 12.7 4.9 4.0 2.4 11.0 11.0 4.5 1.8 2.3 5.8 2.9 3.7 2.1 5.6 4.6 6.3 6.3 8.1 5.3 3.1 2.5 4.4 10.5 5.4 5.0 5.8 5.4 4.1 10.9 9.8 3.4 5.2 3.3 5.0 4.2 3.6 5.5 5.6 9.2 4.0 3.0 6.5 6.1 5.4 5.9 5.1 4.0 3.3 7.1 6.2 5.9 8.8 30.2 5.0 9.7 3.8 4.4 4.9 3.3 3.2 1.9 6.0 4.1 6.9 13.5 10.8 2.2 5.7 14.2 10.9 10.2 14.5 17.5 11.1 23.8 11.4 12.8 13.5 12.5 15.1 12.7 16.2 13.4 1.4 9.9 28.7 13.0 12.6 8.8 11.7 12.2 14.2 17.6 12.3 11.2 12.0 11.7 11.9 11.8 11.5 12.7 14.9 0.0 6.5 8.8 10.4 6.2 9.1 9.4 4.0 9.6 24.3 24.3 24.6 14.3 10.0 16.5 2.1 11.9 11.9 8.4 54.8 18.7 6.2 8.9 7.2 12.9 18.7 9.9 14.2 28.4 20.3 14.9 8.2 8.7 4.5 11.1 12.5 25.4 27.4 11.8 13.5 8.0 8.2 11.6 14.1 10.7 12.2 12.5 16.0 8.4 18.4 18.8 5.2 20.1 12.1 14.1 7.6 21.8 11.2 12.1 15.5 52.0 5.5 11.6 6.6 23.0 10.5 15.6 9.6 10.8 11.2 7.7 8.8 16.5 8.4 12.3 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698109-39782792 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 29.9 19.4 13.5 23.4 17.5 21.4 21.7 20.9 24.5 16.0 9.2 35.8 31.2 17.8 17.7 26.2 12.7 12.9 18.4 18.3 14.9 26.7 45.4 16.4 20.1 12.9 14.0 13.6 13.2 20.4 15.8 24.4 13.1 19.8 24.2 21.0 16.9 14.9 37.3 22.6 24.8 17.2 7.8 18.0 31.8 16.5 14.2 22.4 23.8 25.6 18.0 20.2 17.2 16.0 91.3 90.7 49.3 45.6 29.8 28.7 82.8 122.8 26.4 32.8 34.0 138.0 91.1 114.3 105.2 35.0 79.8 39.0 95.4 54.7 51.9 76.1 70.0 145.7 88.9 121.6 38.4 159.0 79.6 27.1 60.2 46.0 49.0 35.2 43.3 49.3 152.9 39.6 33.9 86.6 111.5 89.9 67.7 54.4 69.8 66.3 144.0 44.2 46.0 123.9 103.9 47.4 91.7 34.5 58.9 54.1 44.4 58.2 116.9 49.9 105.7 60.0 114.5 55.3 174.0 121.4 26.9 101.4 59.5 19.6 18.1 24.8 14.4 16.9 13.4 20.7 15.0 13.8 19.7 14.7 11.2 12.6 15.1 14.0 25.4 27.6 16.0 10.5 13.5 17.5 20.9 24.5 18.3 14.9 12.9 14.0 13.1 7.8 14.2 16.0 63.2 57.7 63.1 69.2 53.0 122.9 65.5 74.3 59.7 62.2 65.3 52.5 72.3 52.9 66.7 49.7 29.2 84.5 76.5 143.7 66.5 83.5 144.9 72.0 82.3 65.6 59.7 85.8 115.9 89.4 168.7 59.2 68.3 90.9 34.8 40.1 63.5 113.6 80.2 104.3 113.8 74.5 65.1 77.1 91.8 202.4 65.3 76.5 56.9 89.0 104.0 87.1 56.7 87.0 118.2 139.6 94.3 56.4 55.5 111.4 75.3 98.0 60.7 42.9 39.5 61.8 121.1 145.2 55.1 74.3 137.9 147.5 61.3 54.8 74.1 107.0 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.9;testis: 158.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 341.4;dendritic cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 16.3 17.6 17.1 21.8 17.3 115.9 11.0 15.7 23.7 16.8 10.9 18.5 11.4 17.2 5.5 37.1 15.1 13.1 24.8 25.2 23.8 13.0 11.5 16.2 35.7 17.0 16.5 14.8 7.7 6.8 28.8 13.6 22.2 15.1 9.3 9.4 12.0 6.2 15.5 12.0 16.2 15.0 16.7 25.7 17.6 158.3 18.9 47.8 10.3 5.7 30.9 16.2 17.8 21.3 532.9 279.4 241.3 193.8 15.3 21.6 42.9 419.3 126.1 253.2 229.1 191.1 183.6 508.6 169.5 106.4 304.5 152.9 243.6 109.5 111.4 402.0 810.5 305.8 162.8 62.5 45.1 370.0 286.0 23.8 30.2 186.7 179.1 55.0 100.6 272.7 310.0 347.0 161.3 139.5 503.2 191.3 605.3 147.2 470.6 437.4 185.5 185.8 69.2 111.5 609.3 330.0 534.5 131.2 248.6 72.6 93.8 198.1 155.9 151.9 432.8 130.7 1013.5 277.1 734.4 617.0 159.2 257.5 562.7 0.5 0.8 1.3 0.7 0.6 0.5 2.5 1.0 1.0 0.6 0.6 1.0 0.5 2.4 0.2 0.4 1.3 0.4 0.1 17.1 17.3 15.7 23.7 25.2 23.8 17.0 16.5 22.2 16.7 18.9 21.3 308.0 0.0 3.4 5.9 161.3 162.6 151.2 31.5 81.4 59.3 235.9 341.4 3.1 8.6 9.9 20.2 54.2 87.8 432.7 59.2 15.6 42.8 127.5 89.3 68.2 72.5 92.6 166.5 8.7 30.5 247.9 99.3 44.9 68.0 18.4 200.9 31.8 10.6 65.5 32.0 11.0 69.1 38.7 26.8 125.3 52.2 17.4 131.7 74.7 3.7 36.7 91.1 21.6 7.5 13.5 82.3 44.1 12.4 100.6 82.9 20.4 18.4 9.7 75.7 13.1 125.2 186.7 196.9 174.0 74.1 115.9 59.8 233.3 64.6 55.8 121.1 UBE3C "KIAA0010, KIAA10" ENSG00000009335 "Ubiquitin protein ligase E3C" Q15386 7 157138916-157269370 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039915 Approved Approved "Nucleoplasm,Plasma membrane,Mitochondria" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Mitochondria" "Plasma membrane" "HPA039915: AB_10795264" "unprognostic (2.83e-2)" "unprognostic (9.27e-3)" "unprognostic (2.41e-1)" "unprognostic (2.29e-1)" "unprognostic (1.19e-2)" "unprognostic (3.14e-2)" "unprognostic (1.36e-1)" "unprognostic (7.02e-2)" "unprognostic (2.34e-2)" "unprognostic (1.58e-1)" "unprognostic (3.01e-3)" "unprognostic (8.64e-2)" "prognostic favorable (9.18e-6)" "unprognostic (9.74e-2)" "unprognostic (1.86e-1)" "unprognostic (1.87e-1)" "unprognostic (3.60e-2)" 25.7 17.4 12.0 21.5 13.2 16.2 21.7 17.5 14.1 18.4 18.8 22.3 20.0 19.4 13.4 28.3 18.5 19.1 28.5 13.2 14.1 20.3 22.9 19.0 20.9 14.6 13.4 20.0 22.4 36.2 11.1 17.5 14.9 19.9 23.2 20.2 22.7 22.7 65.6 20.8 20.8 29.2 12.7 18.0 20.9 26.2 14.8 18.6 17.3 58.5 22.8 28.1 17.0 15.0 68.8 53.3 33.5 67.3 58.8 61.3 37.1 74.0 63.4 61.1 61.3 48.3 55.7 36.8 64.0 82.1 79.6 42.4 52.6 68.3 72.0 67.6 48.3 37.6 35.6 35.0 58.4 56.9 52.8 54.8 61.6 68.0 55.9 46.4 72.2 30.3 55.7 39.9 87.6 59.8 56.2 35.9 53.3 61.1 63.6 31.9 37.7 75.9 63.2 74.1 53.5 55.2 72.8 61.9 54.5 37.2 32.0 39.3 65.3 76.6 16.5 190.0 93.3 39.7 42.9 37.0 87.7 83.0 89.5 0.3 1.8 1.1 2.2 2.3 3.0 1.1 2.4 2.4 2.0 1.2 2.2 2.7 0.6 2.1 2.5 1.8 2.8 1.5 12.0 13.2 17.5 14.1 13.2 14.1 14.6 13.4 14.9 12.7 14.8 15.0 23.8 22.4 19.7 52.2 14.2 27.5 17.3 19.0 17.6 34.7 22.4 16.9 33.7 22.8 14.2 25.8 66.7 14.9 25.3 27.3 9.8 20.3 11.6 21.6 27.4 23.4 24.5 14.9 98.9 17.7 17.4 19.6 27.0 24.5 9.5 23.0 23.6 48.3 15.4 32.0 100.7 21.8 12.2 27.6 15.2 10.1 15.5 20.6 5.4 52.5 22.0 9.9 26.8 81.4 96.2 27.5 13.4 25.6 17.5 31.5 20.6 19.1 19.8 39.9 0.0 23.1 21.4 26.6 27.3 37.5 33.2 15.1 20.9 22.3 26.2 28.1 UBQLN2 "Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157" ENSG00000188021 "Ubiquilin 2" Q9UHD9 X 56563627-56567868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Autophagy "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006431, CAB013481" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB013481: AB_2533341, HPA006431: AB_1078707" "unprognostic (1.23e-2)" "unprognostic (2.88e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.66e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.81e-2)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (8.88e-2)" "unprognostic (8.42e-3)" 13.8 20.2 24.9 14.9 26.8 11.1 12.1 19.7 30.6 15.9 12.7 15.7 11.2 16.6 15.9 18.7 17.5 14.5 21.6 27.4 25.5 13.5 19.4 13.8 18.4 20.2 20.4 25.7 10.5 23.6 16.3 15.8 22.1 20.2 12.1 22.2 14.4 20.0 28.0 13.6 12.4 18.4 21.3 14.9 13.1 4.4 22.6 18.9 20.7 22.8 18.6 18.6 11.1 25.5 36.3 26.5 25.9 30.6 58.3 37.0 16.3 28.6 33.9 21.0 23.2 14.9 16.6 27.6 30.5 34.0 32.9 20.7 50.0 31.9 25.3 43.0 30.1 11.2 34.2 15.9 30.6 22.1 23.7 34.7 39.6 28.3 24.6 30.3 18.7 17.6 13.3 29.5 33.6 16.9 28.5 19.2 21.7 11.6 31.1 25.3 33.7 26.3 42.8 27.9 31.9 29.9 41.3 18.1 17.4 45.2 30.4 16.1 21.2 22.2 22.5 32.4 17.5 11.1 14.8 18.9 24.9 23.1 19.3 50.0 23.6 24.1 15.1 31.1 17.1 7.8 22.9 17.7 17.8 8.6 30.3 18.9 20.4 20.9 34.2 6.5 23.5 20.3 24.9 26.8 19.7 30.6 27.4 25.5 20.2 20.4 22.1 21.3 22.6 25.5 13.9 22.4 17.2 0.0 30.5 31.2 41.6 27.4 20.5 42.3 14.5 11.3 37.6 15.7 25.0 18.4 18.8 28.8 15.4 12.1 17.6 20.0 0.1 11.8 22.7 18.9 34.2 18.3 0.0 16.6 26.7 27.9 13.7 15.7 12.7 14.2 18.2 20.3 24.7 42.1 0.0 20.3 18.3 30.7 25.3 1.6 24.8 21.1 17.8 0.0 35.9 22.3 42.2 0.0 0.0 18.9 12.7 36.5 23.5 32.0 20.7 16.4 27.5 35.8 13.1 25.4 29.8 0.3 1.5 32.7 30.4 40.0 28.7 12.2 19.3 35.6 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564029-42693505 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 138.5;Inhibitory neurons: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 38.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 11.0 10.7 8.5 12.7 10.1 17.9 12.9 14.1 11.1 10.3 11.3 12.7 14.4 10.9 11.2 9.5 9.4 8.6 11.2 9.0 8.8 12.1 17.2 11.9 12.7 9.0 8.7 12.2 15.6 15.0 8.8 11.7 9.3 10.5 13.8 29.7 12.0 10.0 22.8 12.2 13.8 10.6 8.6 15.3 12.2 6.2 9.1 13.5 13.3 22.3 11.5 10.8 10.4 14.2 18.5 9.0 10.4 16.4 20.9 20.0 14.0 13.8 14.9 12.0 12.4 13.2 7.4 12.5 10.7 15.0 13.9 18.1 15.1 11.8 15.2 17.1 10.6 20.0 13.3 17.3 17.0 19.6 13.1 14.1 12.7 12.0 12.9 14.8 13.7 17.9 23.7 15.4 11.7 14.9 15.4 17.1 9.5 36.2 8.7 13.6 15.5 19.0 13.8 15.7 12.4 9.8 14.0 13.3 13.9 15.7 13.0 18.7 19.8 10.8 8.4 13.5 10.1 14.1 13.4 18.9 5.7 14.5 6.8 17.7 7.1 15.2 6.5 7.3 5.4 5.2 4.2 5.1 5.5 5.2 4.3 4.8 38.5 5.9 9.8 4.1 5.3 3.4 8.5 10.1 14.1 11.1 9.0 8.8 9.0 8.7 9.3 8.6 9.1 14.2 33.5 16.0 24.6 82.6 33.9 16.6 18.1 14.9 28.5 43.0 20.4 15.9 39.3 30.0 22.1 20.2 60.5 17.4 46.6 51.6 17.6 18.5 12.4 27.5 30.8 24.8 12.6 75.1 138.5 15.3 13.4 26.5 34.1 32.9 20.3 31.3 21.8 35.0 13.2 63.9 142.7 22.5 14.2 26.7 28.6 3.9 25.4 26.1 19.6 87.1 43.0 23.5 32.0 123.1 131.4 15.0 29.1 24.0 50.6 22.8 37.2 11.7 27.9 53.5 39.5 30.0 27.2 11.2 10.9 28.1 16.2 17.2 44.0 24.0 21.5 22.7 UBTD1 FLJ11807 ENSG00000165886 "Ubiquitin domain containing 1" Q9HAC8 10 97498924-97571206 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 53.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 6.4;neutrophil: 6.6" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034825 Uncertain Approved "Vesicles,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane, Cytosol" "HPA034825: AB_10602254" "unprognostic (1.52e-1)" "unprognostic (1.48e-1)" "prognostic unfavorable (5.54e-4)" "unprognostic (2.43e-1)" "unprognostic (1.78e-1)" "unprognostic (3.90e-2)" "unprognostic (3.63e-3)" "unprognostic (1.43e-2)" "unprognostic (1.66e-3)" "unprognostic (9.25e-3)" "unprognostic (2.45e-1)" "unprognostic (4.78e-1)" "unprognostic (6.62e-3)" "unprognostic (8.80e-2)" "unprognostic (1.49e-1)" "unprognostic (1.47e-3)" "unprognostic (3.50e-3)" 18.8 11.1 14.9 5.7 15.2 8.8 14.7 16.8 17.0 16.5 12.6 10.3 1.8 13.5 4.0 9.5 13.6 7.0 35.1 13.5 15.8 29.2 18.6 29.8 3.1 17.7 17.1 8.7 9.6 3.6 15.9 3.8 16.2 13.4 0.6 6.0 11.2 7.5 34.2 49.5 5.5 3.6 16.1 11.0 9.4 60.3 18.9 1.6 14.6 11.2 1.1 12.4 16.3 14.6 18.1 17.7 4.6 23.0 18.9 17.8 5.4 20.3 29.4 21.3 16.3 12.0 15.4 2.2 24.1 13.8 13.4 21.4 4.6 27.2 3.0 5.6 9.1 2.2 5.5 15.2 27.2 2.0 5.9 24.6 9.0 23.3 5.7 32.8 34.3 4.7 1.2 3.3 13.9 8.6 0.9 18.5 7.5 3.4 32.1 1.8 8.1 2.1 16.7 6.7 1.5 4.8 9.2 5.6 27.1 4.0 20.8 13.6 37.5 26.9 16.4 28.4 26.8 4.2 5.1 0.9 22.7 12.3 14.3 1.0 2.6 6.4 0.1 0.7 0.1 0.3 0.0 0.0 1.4 0.0 0.0 0.0 6.6 0.0 0.7 0.9 0.3 0.5 14.9 15.2 16.8 17.0 13.5 15.8 17.7 17.1 16.2 16.1 18.9 14.6 5.0 41.7 28.6 13.1 1.1 26.0 8.8 32.2 19.4 3.8 10.0 4.8 15.5 8.6 21.2 7.3 4.2 3.5 0.6 1.5 11.7 18.9 53.5 8.2 8.7 23.8 0.0 0.4 5.6 12.8 12.8 11.6 2.6 4.0 0.0 0.8 7.9 7.0 25.8 6.7 5.9 0.2 10.2 10.1 18.9 33.8 12.8 10.3 10.6 12.2 8.4 16.5 2.1 2.0 14.5 22.1 0.1 9.4 3.0 14.0 0.0 10.4 19.1 18.6 13.1 8.5 10.3 7.5 7.9 8.2 29.7 2.9 1.9 1.5 0.4 7.6 UCP3 SLC25A9 ENSG00000175564 "Uncoupling protein 3" P55916 11 74000277-74009085 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Transport "Diabetes mellitus, Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 80 "skeletal muscle: 393.2;tongue: 263.1" "Cell type enhanced" "Detected in some" "Early spermatids: 15.4;Late spermatids: 14.0;NK-cells: 6.2;Skeletal myocytes: 6.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 4 "HDLM-2: 15.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "CAB010771, HPA072225" Enhanced Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB010771: AB_261839, HPA072225: AB_2686498" "unprognostic (3.76e-3)" "unprognostic (1.24e-1)" "unprognostic (2.82e-1)" "unprognostic (5.98e-2)" "unprognostic (1.12e-1)" "unprognostic (2.49e-2)" "unprognostic (3.95e-3)" "unprognostic (6.61e-2)" "unprognostic (1.25e-1)" "unprognostic (8.58e-2)" "unprognostic (2.13e-4)" "unprognostic (1.61e-2)" "unprognostic (3.25e-6)" "unprognostic (2.68e-1)" "unprognostic (1.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.50e-4)" 1.2 1.7 2.5 1.3 2.6 2.2 1.3 3.9 3.0 1.4 2.3 1.7 0.7 1.4 2.0 2.9 1.5 0.8 2.4 2.7 2.1 1.7 1.3 1.4 1.3 2.4 2.1 1.1 1.1 0.9 2.7 0.5 2.3 1.8 0.7 4.0 3.7 0.7 393.2 1.4 1.7 0.8 1.8 3.1 1.2 3.9 2.4 1.6 2.6 263.1 0.7 1.4 0.9 2.8 0.2 1.8 1.7 1.5 0.7 0.3 0.3 0.5 0.4 0.4 0.2 0.4 0.4 0.9 0.2 0.3 0.2 1.9 0.7 0.3 0.7 15.8 0.5 0.3 2.4 0.2 0.5 1.1 1.4 0.4 1.1 1.1 0.1 0.3 0.5 0.9 0.4 1.2 0.6 1.0 0.7 1.4 0.9 1.4 1.1 1.4 3.6 0.5 0.9 0.5 0.9 1.0 0.4 0.7 0.6 0.3 0.2 1.0 0.3 0.2 1.1 0.6 1.1 1.4 1.5 0.7 0.2 1.0 0.5 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.3 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.5 2.6 3.9 3.0 2.7 2.1 2.4 2.1 2.3 1.8 2.4 2.8 0.8 0.0 0.0 1.6 0.8 0.1 0.1 0.5 0.6 2.3 1.0 1.1 0.7 0.0 1.1 0.0 0.0 0.3 2.0 0.3 0.0 0.3 15.4 1.2 1.1 0.6 0.0 0.4 1.6 0.5 0.2 0.4 0.0 0.8 0.0 0.7 1.1 0.3 0.7 0.0 1.6 0.5 2.0 0.8 0.0 14.0 0.0 0.6 0.0 1.0 0.7 0.8 6.2 0.5 0.6 0.4 0.1 0.7 0.5 0.2 0.3 0.1 3.0 2.1 0.0 6.5 0.5 1.5 0.8 0.4 0.3 0.3 1.5 0.3 0.6 0.1 ULBP1 RAET1I ENSG00000111981 "UL16 binding protein 1" Q9BZM6 6 149963943-149973715 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.4;lung: 1.7;testis: 3.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.2;Breast myoepithelial cells: 3.0;Respiratory ciliated cells: 2.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebellum: 4.4;cerebral cortex: 1.9;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 16.5;HAP1: 29.3;HDLM-2: 17.1;HHSteC: 18.0;JURKAT: 26.1" "HPA007547, HPA071005" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA007547: AB_1079430, HPA071005: AB_2686332" "unprognostic (8.94e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-2)" "unprognostic (2.33e-2)" "unprognostic (3.28e-4)" "unprognostic (6.69e-3)" "unprognostic (5.27e-2)" "unprognostic (2.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.57e-12)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-2)" 0.2 0.1 0.1 0.2 0.1 0.3 0.0 4.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 1.6 0.2 0.4 0.1 1.7 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.2 2.1 1.0 1.6 0.0 3.3 6.8 3.2 3.0 0.9 0.6 2.0 0.2 3.1 3.5 0.7 16.5 6.9 0.7 29.3 1.4 2.7 17.1 3.8 0.3 0.6 0.0 18.0 0.1 1.2 9.1 6.8 13.6 2.5 0.0 1.1 26.1 3.3 0.0 3.5 2.7 4.3 0.0 0.5 1.4 2.3 0.0 1.3 0.5 0.0 0.4 1.0 0.4 4.4 2.0 0.0 1.3 2.9 6.4 0.3 1.6 0.0 1.4 0.0 0.5 0.7 2.3 8.7 5.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.1 4.4 1.9 1.6 0.2 0.1 0.2 0.5 0.1 0.1 0.2 1.6 6.4 2.2 0.0 0.5 0.1 0.5 0.0 0.6 0.0 1.0 3.0 0.9 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.1 0.2 0.6 1.1 0.0 0.0 0.1 0.6 0.0 1.6 0.0 0.7 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.3 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 2.2 0.0 0.0 1.6 1.3 0.2 0.2 2.5 0.6 0.0 0.7 0.2 0.3 0.1 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 UNC5A "KIAA1976, UNC5H1" ENSG00000113763 "Unc-5 netrin receptor A" Q6ZN44 5 176810519-176880898 "Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 30.4;pituitary gland: 14.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 54.4;Inhibitory neurons: 19.4;Muller glia cells: 13.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.5" "Group enriched" "Detected in many" 6 "amygdala: 10.5;basal ganglia: 15.1;cerebral cortex: 30.4;hippocampal formation: 16.3;white matter: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 86.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071450 Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA071450: AB_2686397" "unprognostic (5.95e-2)" "unprognostic (1.15e-1)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.23e-4)" "unprognostic (5.26e-2)" "unprognostic (2.23e-1)" "unprognostic (6.66e-3)" "unprognostic (5.06e-3)" "unprognostic (3.52e-1)" "unprognostic (1.36e-1)" "unprognostic (5.07e-1)" "unprognostic (9.95e-2)" "unprognostic (3.77e-5)" "unprognostic (6.39e-2)" "unprognostic (2.89e-1)" "unprognostic (2.27e-1)" "unprognostic (5.17e-2)" 0.4 7.5 10.5 0.3 15.1 0.4 0.7 2.6 30.4 0.3 0.0 0.1 0.4 0.4 0.2 0.1 0.6 0.2 0.3 16.3 0.0 0.1 0.1 0.3 0.9 0.0 0.0 0.1 1.8 0.0 14.7 0.0 0.0 0.2 0.0 3.1 2.5 0.0 0.0 0.5 0.1 0.1 0.0 0.1 1.0 0.7 0.0 0.1 0.5 0.0 0.0 0.2 0.1 11.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 1.4 3.5 0.0 0.0 0.0 2.5 10.1 0.0 86.4 3.9 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.5 15.1 2.6 30.4 16.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 4.7 0.6 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.9 0.1 0.9 0.0 0.0 54.4 0.0 0.0 0.0 0.0 1.6 0.0 2.0 0.0 0.0 0.0 5.0 19.4 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.7 0.0 13.9 0.0 7.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UNC79 KIAA1409 ENSG00000133958 "Unc-79 homolog, NALCN channel complex subunit" Q9P2D8 14 93333219-93707876 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;pituitary gland: 11.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 524.0;Inhibitory neurons: 463.6;Oligodendrocyte precursor cells: 270.4;Oligodendrocytes: 202.6" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 4.3;SCLC-21H: 3.0;SH-SY5Y: 1.9;U-937: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071881 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA071881: AB_2732189" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.70e-2)" "unprognostic (6.91e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-2)" "unprognostic (2.99e-2)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.73e-3)" "unprognostic (8.03e-3)" "unprognostic (2.87e-1)" "unprognostic (3.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.57e-2)" "unprognostic (3.03e-2)" "unprognostic (7.47e-2)" 0.0 0.7 2.2 0.0 2.8 0.0 0.0 5.1 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.1 1.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.2 11.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 2.5 0.4 0.0 0.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.0 0.0 0.1 0.1 3.0 1.9 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 5.1 4.7 2.1 1.9 0.0 0.1 0.0 0.0 0.4 2.3 0.3 0.0 0.0 89.8 0.4 0.3 0.3 0.5 0.0 41.9 0.3 0.3 2.8 0.0 0.1 0.0 10.4 0.1 0.3 0.7 0.0 0.3 36.9 4.8 0.9 0.6 0.0 0.4 524.0 0.2 0.1 0.6 1.1 0.8 0.0 0.3 0.4 0.2 0.3 40.4 463.6 0.3 0.0 0.6 0.4 16.4 0.6 0.4 0.0 23.4 0.1 2.1 0.0 270.4 202.6 0.4 0.1 0.4 0.0 0.3 0.6 1.9 0.9 5.7 0.0 0.5 0.8 3.4 2.5 0.2 0.3 0.7 0.2 0.5 0.2 0.3 UQCC1 "BFZB, C20orf44, CBP3, FLJ10850, UQCC" ENSG00000101019 "Ubiquinol-cytochrome c reductase complex assembly factor 1" Q9NVA1 20 35302566-35412031 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 106.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 64.6;Inhibitory neurons: 68.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034875 Approved Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 39: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nucleoplasm, Actin filaments" "HPA034875: AB_10603226" "unprognostic (9.66e-2)" "unprognostic (3.93e-1)" "unprognostic (3.45e-1)" "unprognostic (8.72e-3)" "unprognostic (4.01e-1)" "unprognostic (1.31e-1)" "unprognostic (5.73e-2)" "unprognostic (2.75e-1)" "unprognostic (2.82e-2)" "unprognostic (7.66e-2)" "unprognostic (3.42e-2)" "unprognostic (7.01e-2)" "unprognostic (6.72e-3)" "unprognostic (3.23e-1)" "unprognostic (3.60e-1)" "unprognostic (5.27e-2)" "unprognostic (1.34e-2)" 19.4 30.0 22.0 13.8 24.3 4.6 16.5 21.9 27.7 20.1 20.9 26.0 18.9 18.6 22.9 18.8 20.6 12.6 55.3 22.4 23.0 28.6 27.1 15.8 17.9 24.1 23.5 19.8 15.9 37.2 23.9 14.9 26.6 19.7 25.8 29.5 18.7 18.4 106.8 16.3 19.3 18.5 19.9 19.7 23.0 17.6 22.9 21.2 22.3 105.7 21.9 20.1 18.0 22.8 20.2 28.6 33.5 32.2 34.1 38.4 4.8 38.5 43.3 70.7 48.1 97.7 39.4 66.6 68.5 26.1 60.7 53.5 60.0 70.0 52.6 19.0 24.2 89.2 41.3 80.3 22.7 54.2 25.6 37.6 72.3 37.9 48.8 51.2 24.6 53.5 39.9 23.9 50.0 26.8 58.6 29.2 25.4 42.0 61.5 31.4 50.0 37.9 67.6 26.2 46.4 28.7 32.9 148.9 34.0 28.1 23.9 34.6 23.5 46.2 28.8 25.9 34.6 30.1 37.2 26.5 79.7 31.1 36.8 28.6 10.2 14.2 14.8 14.3 18.3 12.3 13.7 14.7 16.0 15.7 16.7 14.7 0.3 22.3 10.2 14.4 14.2 12.6 22.0 24.3 21.9 27.7 22.4 23.0 24.1 23.5 26.6 19.9 22.9 22.8 7.0 0.0 7.8 51.6 7.0 6.4 9.3 18.1 6.8 20.7 7.8 5.8 44.0 10.0 11.8 16.5 8.4 22.9 5.3 13.9 60.7 18.2 15.1 10.5 8.5 10.5 12.0 5.2 64.6 13.1 15.7 9.2 7.7 6.9 8.2 17.5 6.1 14.2 11.6 18.5 68.9 9.1 18.3 6.6 3.9 8.6 10.5 5.8 14.2 33.7 13.2 16.7 10.3 44.2 50.3 19.1 6.6 12.0 5.0 8.4 10.9 19.4 14.8 22.8 6.6 9.6 11.9 24.6 18.2 6.2 5.3 17.4 6.2 19.7 13.2 9.6 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 168.3" "Group enriched" "Detected in many" 5 "Early spermatids: 460.0;Late spermatids: 1094.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 14.5;U-266/70: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 7.0 13.4 11.9 1.6 22.6 1.9 4.1 18.8 19.0 6.0 32.7 10.2 13.9 5.2 5.7 9.8 11.6 2.3 73.5 18.6 9.4 53.4 18.9 3.4 0.1 12.0 13.1 6.2 18.1 24.2 18.9 1.3 7.7 4.1 6.0 76.2 7.6 3.0 168.3 12.8 17.4 6.8 8.2 0.6 6.2 86.5 15.1 0.6 3.8 62.8 0.6 4.5 4.8 17.5 6.0 0.5 0.9 3.2 0.1 0.2 1.3 0.7 0.4 0.0 0.6 6.1 0.8 10.2 1.8 1.1 1.4 1.0 7.9 2.9 0.2 7.2 1.0 2.8 4.4 12.5 2.7 0.0 2.8 0.9 0.6 0.7 2.0 1.3 0.6 7.6 14.5 0.8 1.7 4.1 0.0 0.6 1.6 2.0 1.3 0.1 2.1 1.5 4.6 0.3 11.9 3.6 3.4 2.6 0.7 1.7 8.8 6.2 0.0 0.0 1.5 0.8 1.0 56.9 13.5 0.2 0.1 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 22.6 18.8 19.0 18.6 9.4 12.0 13.1 7.7 8.2 15.1 17.5 0.6 3.2 2.7 10.7 0.6 2.4 5.3 1.5 1.2 75.2 3.3 2.4 85.2 7.2 6.1 5.5 95.9 0.5 1.6 25.5 113.5 3.1 460.0 39.0 3.0 3.6 0.0 0.4 15.7 1.6 0.9 7.4 2.0 8.4 0.0 2.0 2.2 23.0 17.2 10.1 11.6 2.0 0.0 1.3 2.9 1094.1 6.5 2.1 0.0 1.9 0.0 49.7 0.0 8.0 12.5 1.2 11.8 7.2 0.1 1.1 41.3 41.6 35.0 140.0 19.7 43.3 24.0 50.5 16.5 12.9 4.0 1.4 1.3 0.5 2.6 2.9 USP20 KIAA1003 ENSG00000136878 "Ubiquitin specific peptidase 20" Q9Y2K6 9 129834698-129881828 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Endocytosis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "JURKAT: 95.9;K-562: 60.2;MOLT-4: 56.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006287, HPA007008" Uncertain Supported Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Nucleoplasm, Plasma membrane, Cytosol" "HPA006287: AB_1080510, HPA007008: " "unprognostic (2.64e-2)" "prognostic favorable (8.01e-4)" "prognostic unfavorable (2.48e-4)" "prognostic favorable (4.01e-4)" "unprognostic (4.69e-1)" "unprognostic (1.89e-2)" "unprognostic (2.25e-1)" "unprognostic (2.55e-3)" "unprognostic (1.24e-1)" "unprognostic (7.89e-2)" "prognostic favorable (1.54e-7)" "unprognostic (2.09e-1)" "prognostic favorable (5.65e-5)" "unprognostic (1.76e-2)" "unprognostic (1.20e-1)" "unprognostic (1.19e-2)" "unprognostic (1.24e-2)" 8.1 12.0 8.7 13.5 8.0 22.6 8.3 4.8 8.7 12.5 2.5 13.6 8.2 12.5 4.2 7.9 12.1 7.7 7.5 7.8 10.6 7.6 7.4 8.4 18.3 10.2 9.1 13.5 10.9 8.4 18.4 6.7 10.0 14.8 4.9 6.7 11.4 13.2 10.9 12.1 12.5 8.2 5.4 13.9 9.9 10.0 8.9 32.3 18.7 7.5 11.8 14.9 10.1 6.5 6.0 5.8 10.0 13.4 12.8 10.8 14.1 9.5 7.9 7.1 4.9 4.7 6.5 8.1 8.0 9.3 8.0 14.7 6.0 6.7 2.9 43.4 7.9 14.9 17.0 3.3 8.8 14.2 10.6 9.6 9.8 9.3 7.0 12.4 7.7 95.9 60.2 9.9 4.4 15.9 56.4 33.6 7.9 12.7 13.6 9.4 11.2 14.0 5.5 6.5 2.2 11.0 11.0 13.9 9.1 5.9 14.4 19.9 11.5 7.8 3.5 10.5 6.3 9.7 15.3 5.7 15.5 18.6 7.4 1.0 1.9 5.4 8.6 1.5 9.1 3.7 8.7 8.3 2.6 3.4 9.8 8.9 2.8 10.0 1.5 2.1 11.5 6.3 8.7 8.0 4.8 8.7 7.8 10.6 10.2 9.1 10.0 5.4 8.9 6.5 3.0 9.6 6.9 16.3 9.2 2.8 2.2 2.5 4.0 7.8 6.4 8.0 7.7 4.3 3.0 1.8 4.2 5.9 9.4 6.2 3.9 2.4 2.1 4.1 6.3 4.3 8.4 12.8 17.0 4.0 2.5 4.6 8.2 5.7 1.3 6.8 6.4 6.1 3.3 10.1 21.1 4.6 4.1 1.6 3.8 3.3 6.2 6.0 3.6 11.2 3.1 5.3 11.3 9.5 14.3 2.7 5.0 4.9 6.7 3.0 4.1 2.9 5.0 6.3 0.0 4.3 5.7 12.1 6.0 4.8 2.0 6.2 19.3 2.9 5.2 1.6 USP21 "USP16, USP23" ENSG00000143258 "Ubiquitin specific peptidase 21" Q9UK80 1 161159450-161165723 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Ubl conjugation pathway" "Activator, Chromatin regulator, Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 16.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028397 Uncertain Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA028397: AB_10603227" "unprognostic (9.17e-2)" "unprognostic (1.44e-1)" "unprognostic (3.95e-2)" "prognostic unfavorable (7.05e-4)" "unprognostic (1.22e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (1.68e-4)" "unprognostic (5.35e-2)" "unprognostic (6.73e-2)" "unprognostic (2.76e-2)" "unprognostic (3.87e-3)" "unprognostic (1.31e-2)" "prognostic unfavorable (9.50e-6)" "unprognostic (2.45e-1)" "unprognostic (3.28e-1)" "unprognostic (2.13e-2)" "prognostic favorable (3.35e-5)" 12.2 15.3 19.6 11.9 20.7 15.0 14.3 18.5 22.8 19.4 18.3 17.6 13.6 18.2 12.0 16.4 28.0 12.0 13.0 19.4 18.4 14.5 10.8 13.1 16.1 19.2 19.7 23.2 16.4 17.1 15.7 13.2 18.7 17.7 11.0 12.9 16.5 20.3 20.9 20.8 15.9 12.6 17.3 17.8 16.4 14.2 20.1 18.4 18.5 17.7 14.0 17.6 16.8 22.1 12.5 20.6 26.9 26.2 21.1 17.5 16.5 9.1 14.6 24.2 18.9 19.4 23.3 16.0 14.6 11.2 15.1 20.7 17.6 17.5 13.2 30.8 30.0 19.3 34.1 15.3 15.2 17.4 13.4 14.8 23.0 16.6 23.9 27.1 17.3 35.0 28.4 21.6 15.6 22.6 30.7 26.9 25.2 24.3 26.1 28.8 9.0 26.5 14.4 14.9 24.2 31.5 17.2 17.2 13.9 20.1 37.3 27.5 10.1 16.9 14.8 11.9 15.3 42.9 36.5 23.9 15.3 14.7 15.5 15.2 10.0 17.1 12.6 6.4 14.6 11.0 11.5 13.2 10.8 11.3 13.1 12.3 8.4 13.3 7.6 10.8 12.3 11.0 19.6 20.7 18.5 22.8 19.4 18.4 19.2 19.7 18.7 17.3 20.1 22.1 4.5 0.0 3.7 5.2 6.5 1.5 1.8 2.4 16.5 5.0 4.9 4.1 3.9 8.6 2.9 1.8 6.2 4.9 3.6 3.6 1.9 2.0 1.0 6.3 5.7 4.4 5.4 10.7 2.4 2.3 2.3 5.1 9.2 3.7 2.5 4.5 5.3 2.1 2.2 0.0 2.7 4.0 4.1 4.8 0.8 1.0 5.0 2.1 1.8 1.9 1.2 3.3 5.2 2.0 4.6 2.0 2.4 4.1 7.8 2.7 3.5 2.5 9.5 5.2 6.6 2.0 5.2 5.3 3.2 10.7 1.4 3.1 5.6 3.1 4.1 1.5 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 131.8;Late spermatids: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 25.2 20.3 24.2 26.5 26.3 53.7 24.9 24.5 28.2 27.7 27.1 25.4 18.3 24.4 21.6 26.0 22.4 18.3 26.5 23.7 23.4 21.8 20.2 29.5 30.9 23.9 24.4 24.5 19.0 24.1 16.4 23.3 23.9 23.7 23.4 26.9 21.0 21.7 31.6 31.4 22.5 24.0 22.4 33.7 20.2 28.0 24.8 37.0 23.0 28.8 33.7 25.8 25.0 24.5 14.2 15.8 21.6 28.8 38.7 40.1 14.7 36.4 32.9 46.7 41.3 16.8 34.8 27.1 14.4 53.9 27.4 18.9 28.6 52.6 42.5 42.1 8.4 60.3 31.9 19.6 57.0 32.5 34.0 42.8 23.3 51.0 41.5 34.3 55.0 29.9 21.6 41.6 42.1 24.5 38.3 55.8 18.7 17.7 26.9 15.6 13.3 23.9 37.5 29.2 17.5 24.0 27.2 19.3 14.0 21.6 13.5 51.2 50.1 31.1 17.2 39.6 22.5 33.6 17.3 38.6 28.6 50.1 36.5 70.1 83.6 94.8 48.1 69.2 53.7 51.0 50.2 48.9 74.6 41.4 47.7 42.2 179.2 72.4 81.2 28.4 59.7 78.0 24.2 26.3 24.5 28.2 23.7 23.4 23.9 24.4 23.9 22.4 24.8 24.5 24.3 41.7 25.1 28.1 24.7 18.7 17.9 17.2 22.2 17.5 10.9 10.3 17.9 10.0 23.2 20.2 20.9 22.7 27.9 13.6 21.5 16.5 131.8 17.3 18.3 22.1 10.7 31.6 30.8 13.6 14.3 17.9 27.5 21.1 33.6 21.4 17.5 14.6 24.0 11.8 26.4 13.8 16.2 38.6 21.0 104.9 15.5 34.2 16.0 16.9 36.0 13.9 23.7 25.6 20.2 18.9 7.6 19.2 29.2 17.6 14.5 13.4 28.6 20.5 13.1 18.4 17.0 35.3 14.5 17.9 18.5 24.2 29.4 17.0 13.9 14.5 USP53 KIAA1350 ENSG00000145390 "Ubiquitin specific peptidase 53" Q70EK8 4 119212587-119295517 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 586.8;Microglial cells: 269.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 327.9;SK-MEL-30: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035844, HPA035845" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA035844: AB_10669532, HPA035845: AB_2674817" "unprognostic (9.33e-2)" "unprognostic (1.49e-2)" "prognostic favorable (3.15e-6)" "unprognostic (4.37e-3)" "unprognostic (4.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.54e-6)" "prognostic favorable (3.58e-8)" "unprognostic (9.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" 37.8 14.4 5.6 5.7 5.8 0.9 25.3 6.1 6.2 18.5 11.8 16.3 5.7 13.1 13.1 17.0 30.6 10.2 24.0 4.9 7.3 19.9 7.3 29.4 12.4 9.4 8.1 9.4 24.6 8.1 10.3 10.5 7.3 9.2 16.1 3.4 12.7 11.5 33.5 11.7 9.7 10.2 6.5 7.2 15.1 7.8 8.6 5.4 10.5 51.7 8.0 12.7 12.0 5.5 11.4 6.8 2.4 0.0 60.5 60.4 13.6 70.6 327.9 6.2 8.1 7.4 10.4 46.1 2.5 21.1 12.1 5.5 5.5 5.3 16.1 6.1 4.5 3.1 5.2 2.6 47.2 3.9 0.7 20.3 15.0 21.9 31.0 11.7 29.8 3.0 7.3 1.7 8.4 2.5 2.9 5.2 6.7 7.0 3.8 0.9 11.4 9.2 16.4 7.2 3.8 3.0 3.9 27.5 102.4 13.3 7.0 2.7 32.3 2.0 7.0 26.3 6.4 3.3 5.2 7.8 31.4 1.7 7.9 1.3 0.0 0.0 0.4 0.0 0.5 0.7 1.0 0.8 0.1 0.7 1.9 1.0 0.2 0.9 0.0 0.3 0.9 0.3 5.6 5.8 6.1 6.2 4.9 7.3 9.4 8.1 7.3 6.5 8.6 5.5 27.6 35.3 44.5 80.6 18.5 61.8 73.6 21.2 48.3 17.8 74.1 46.6 99.0 32.9 33.9 119.5 29.2 48.4 15.1 207.8 45.0 33.4 5.6 167.2 45.9 35.7 34.6 4.8 32.4 62.7 17.3 86.0 41.8 586.8 70.8 19.8 23.9 30.5 9.3 25.2 32.5 80.4 52.9 21.3 76.4 7.3 19.0 36.5 14.2 269.8 45.6 25.0 12.3 11.6 11.9 110.6 214.5 10.9 18.6 138.6 46.0 20.1 27.3 31.5 6.6 91.8 32.9 18.0 4.0 62.6 42.3 49.8 26.8 14.8 62.6 124.8 UTP20 "1A6/DRIM, DRIM" ENSG00000120800 "UTP20 small subunit processome component" O75691 12 101280105-101386618 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049341 Supported "Nucleoli,Plasma membrane" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoli "Plasma membrane" "HPA049341: AB_2680720" "unprognostic (3.04e-2)" "unprognostic (1.22e-1)" "unprognostic (3.92e-2)" "unprognostic (1.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (8.34e-2)" "unprognostic (4.30e-2)" "unprognostic (8.15e-3)" "unprognostic (2.81e-1)" "unprognostic (2.22e-2)" "prognostic favorable (8.87e-4)" "unprognostic (2.88e-1)" "unprognostic (3.44e-1)" "unprognostic (8.30e-2)" "unprognostic (6.92e-3)" 4.3 4.2 2.2 5.0 3.7 4.2 5.7 2.9 2.7 5.7 2.5 3.2 2.1 4.6 2.6 4.0 3.8 2.4 3.0 2.3 2.5 3.3 3.0 3.0 5.0 2.8 2.8 6.4 4.8 5.3 2.2 4.3 2.9 3.5 4.2 3.5 5.6 3.3 5.2 4.6 3.1 4.0 2.4 3.6 3.2 5.6 3.3 4.3 4.2 3.9 4.8 5.1 3.5 5.0 8.1 19.9 14.8 6.9 13.0 15.1 18.2 13.8 10.8 21.5 11.8 23.1 5.7 21.6 7.1 15.4 16.2 16.6 33.0 14.2 27.8 9.8 13.4 22.8 10.0 17.3 7.3 38.4 10.2 9.9 7.3 29.9 10.3 8.2 15.0 10.9 36.7 4.3 15.8 10.6 16.8 10.9 38.9 11.3 20.6 18.8 24.2 16.8 9.1 24.4 17.0 11.5 25.8 16.1 15.7 12.2 17.0 8.5 17.1 25.3 12.5 17.8 27.1 7.8 12.6 35.1 13.8 17.2 39.6 0.0 0.2 0.0 0.5 0.3 0.5 0.9 0.5 0.7 0.4 0.6 0.6 0.7 0.0 0.6 0.2 0.8 0.5 0.2 2.2 3.7 2.9 2.7 2.3 2.5 2.8 2.8 2.9 2.4 3.3 5.0 14.3 9.6 9.9 16.0 16.7 10.1 9.7 7.7 11.4 9.9 8.7 8.4 10.3 7.2 13.6 3.7 10.4 7.8 4.4 3.4 5.9 7.6 1.5 11.4 24.5 12.6 6.6 14.9 17.0 11.6 8.8 13.0 7.7 10.1 13.3 18.6 7.1 7.6 5.8 21.9 17.0 6.3 4.1 6.3 3.5 1.2 9.6 8.6 3.6 8.4 3.3 3.3 4.1 16.1 34.2 5.9 1.9 8.2 13.2 14.5 1.1 3.0 9.0 9.4 6.6 24.9 11.0 22.6 22.3 17.3 11.1 2.9 10.0 23.7 9.8 7.2 UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285701-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 410.3;Early spermatids: 527.1;Late spermatids: 332.1;Microglial cells: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 219.4;HUVEC TERT2: 157.0;TIME: 203.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 52.6 17.4 26.8 25.8 40.5 56.6 40.5 32.7 18.3 40.4 35.6 33.8 17.0 29.8 16.8 27.9 43.5 31.2 24.8 18.4 67.9 30.9 25.3 49.3 34.9 48.6 52.1 37.2 52.1 69.4 7.9 45.8 49.7 39.7 31.7 11.0 26.0 26.1 14.0 27.5 22.3 25.9 40.0 71.5 27.2 59.2 48.8 43.2 68.4 38.9 35.8 25.2 16.0 31.0 27.2 22.6 39.3 51.0 66.5 60.5 23.4 39.0 37.8 31.1 45.2 86.1 9.8 8.4 33.6 88.4 36.6 15.6 219.4 32.9 44.6 90.6 25.5 32.2 24.9 51.6 26.3 36.1 0.7 35.5 6.8 46.2 24.1 29.3 157.0 25.1 2.0 22.7 44.1 18.1 28.7 15.5 15.9 16.6 23.9 25.7 70.2 0.8 35.9 0.7 49.7 0.9 60.8 8.4 23.5 59.5 33.3 48.2 203.6 29.8 37.0 15.5 37.6 17.7 25.3 1.3 18.2 21.5 49.5 41.2 40.9 23.2 39.5 120.8 28.3 25.7 24.9 33.0 17.2 35.7 21.8 22.8 34.5 37.6 173.9 50.4 22.2 13.9 26.8 40.5 32.7 18.3 18.4 67.9 48.6 52.1 49.7 40.0 48.8 31.0 267.0 410.3 138.7 148.2 101.2 29.4 31.7 17.2 40.9 6.5 47.4 32.1 56.0 28.6 111.0 31.3 0.0 94.4 175.1 10.9 0.0 25.3 527.1 61.2 51.5 171.8 31.2 19.8 61.2 32.0 6.9 51.6 76.5 87.5 29.7 22.8 83.6 15.6 22.3 60.6 161.4 16.9 8.2 109.7 45.9 332.1 23.9 97.6 39.2 425.3 79.8 29.1 171.0 68.9 4.1 28.1 9.3 33.4 70.3 25.4 3.6 7.1 87.3 4.3 144.7 151.0 157.8 6.6 6.6 33.7 45.5 129.3 108.0 32.0 22.3 19.2 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VAMP8 EDB ENSG00000118640 "Vesicle associated membrane protein 8" Q9BV40 2 85561562-85582031 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiviral defense, Autophagy, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 873.4;NB-4: 1362.5;U-937: 912.8" "Low region specificity" "Detected in all" "HPA006882, HPA007215, CAB037132, CAB037147" Enhanced Approved "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA 220000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Golgi apparatus, Plasma membrane" Nucleoplasm "CAB037132: AB_1080547, CAB037147: AB_1080544, HPA006882: AB_1858716, HPA007215: " "unprognostic (1.00e-1)" "unprognostic (1.16e-1)" "unprognostic (7.46e-3)" "unprognostic (1.13e-1)" "unprognostic (7.33e-2)" "unprognostic (1.31e-1)" "unprognostic (1.76e-2)" "unprognostic (3.79e-3)" "unprognostic (3.83e-2)" "unprognostic (4.15e-1)" "unprognostic (2.74e-2)" "unprognostic (8.62e-2)" "unprognostic (1.57e-3)" "unprognostic (1.92e-2)" "unprognostic (2.16e-1)" "prognostic favorable (8.07e-9)" "prognostic favorable (1.59e-6)" 74.0 34.7 26.9 148.4 28.2 299.7 225.1 28.7 53.8 121.8 51.6 250.6 229.9 30.6 144.5 303.1 166.1 119.2 24.6 26.5 29.9 280.1 247.4 266.5 212.4 35.6 31.6 10.4 182.5 270.3 33.7 265.7 34.3 107.7 300.9 4.4 322.5 90.4 24.3 210.2 252.1 71.4 31.9 175.9 228.4 23.4 35.5 173.5 126.0 27.3 311.7 198.0 150.0 36.5 255.0 33.2 2.6 2.3 2.4 1.4 241.6 0.7 0.3 0.2 0.3 191.2 225.2 56.8 174.4 1.2 17.9 175.2 2.4 451.6 0.6 232.3 173.7 290.3 104.4 220.7 3.3 873.4 287.1 2.3 317.5 0.3 72.3 1.2 58.2 1.2 214.9 11.6 103.8 363.9 0.8 1362.5 3.2 315.9 26.0 5.2 8.9 381.7 516.9 384.3 8.4 2.9 120.9 628.3 19.4 126.3 231.4 665.4 113.9 0.3 15.3 2.9 2.7 3.0 151.1 340.0 2.6 912.8 1.1 601.3 868.6 328.4 469.3 740.3 455.6 519.3 537.0 463.3 787.3 508.3 423.2 442.0 52.4 556.3 460.0 2135.6 665.3 1536.0 26.9 28.2 28.7 53.8 26.5 29.9 35.6 31.6 34.3 31.9 35.5 36.5 39.4 371.8 283.2 1.3 147.7 259.1 303.3 800.9 164.4 1.2 289.7 251.7 6.3 356.0 662.1 366.0 0.0 980.8 447.1 832.3 765.0 630.7 28.0 231.3 22.8 46.1 129.1 147.4 0.1 730.0 460.4 35.6 188.6 212.9 269.4 3.3 163.1 314.8 1191.1 0.0 0.1 391.8 545.3 1000.4 488.7 49.1 9.3 537.2 352.2 2.8 686.1 7.9 375.9 0.0 0.5 865.5 843.2 7.5 103.0 302.7 1184.0 1046.8 600.5 2.0 46.0 21.4 56.5 48.0 8.3 239.8 329.7 877.8 219.5 13.8 299.4 602.0 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VASP ENSG00000125753 "Vasodilator stimulated phosphoprotein" P50552 19 45506579-45526983 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Extravillous trophoblasts: 443.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 52.7" "Group enriched" "Detected in all" 7 "granulocytes: 52.7;monocytes: 22.7" "Cell line enhanced" "Detected in all" "HMC-1: 270.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004612, HPA005724" Enhanced Supported "Plasma membrane,Cell Junctions,Focal adhesion sites" NA NA 32000000 "Cluster 52: Eosinophils - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cell Junctions, Focal adhesion sites" "CAB004612: AB_2213431, HPA005724: AB_1858721" "unprognostic (3.07e-2)" "unprognostic (1.07e-2)" "unprognostic (4.70e-2)" "unprognostic (7.85e-3)" "unprognostic (8.31e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (3.49e-5)" "unprognostic (1.66e-3)" "unprognostic (1.58e-1)" "unprognostic (1.30e-2)" "unprognostic (3.64e-3)" "unprognostic (4.39e-1)" "prognostic unfavorable (5.91e-7)" "unprognostic (1.15e-1)" "unprognostic (1.15e-1)" "unprognostic (1.69e-1)" "unprognostic (1.08e-2)" 54.5 24.6 9.3 75.2 8.3 94.0 42.5 9.2 12.6 37.7 11.0 88.9 61.9 89.1 6.0 37.5 54.4 27.0 36.4 8.1 9.4 39.1 27.3 58.2 48.7 13.0 10.9 22.5 20.6 10.7 17.1 31.5 13.8 43.8 20.4 1.9 30.7 39.1 12.5 32.8 63.6 36.5 11.7 107.0 70.5 14.7 15.0 24.9 27.6 8.5 32.0 71.6 39.0 12.0 68.9 66.3 20.6 35.6 10.2 17.4 50.5 70.2 52.8 47.4 40.9 30.1 142.0 31.2 55.7 56.4 31.3 60.6 6.2 69.5 15.9 87.0 14.8 183.7 32.3 55.4 56.6 68.1 270.1 26.8 38.2 44.5 28.5 38.3 71.1 25.8 112.1 67.5 29.4 53.7 30.3 58.7 36.0 65.1 44.5 21.6 12.6 12.2 40.9 216.2 23.0 16.3 83.6 41.7 48.2 13.0 45.7 115.2 107.0 74.7 74.4 24.7 112.4 32.8 43.3 54.7 52.4 82.3 92.3 13.3 8.5 52.7 4.1 13.9 2.8 3.4 3.3 3.9 5.5 3.3 2.1 2.5 34.5 4.0 22.7 2.1 2.6 5.8 9.3 8.3 9.2 12.6 8.1 9.4 13.0 10.9 13.8 11.7 15.0 12.0 80.9 16.0 19.5 2.9 99.4 98.3 95.6 48.8 37.0 6.9 53.5 57.0 19.0 48.6 41.5 33.1 27.1 67.1 85.9 202.3 17.6 138.6 3.2 33.9 30.5 77.0 114.7 20.0 2.6 98.2 443.6 26.7 81.6 58.1 83.1 17.4 48.5 15.8 160.1 6.7 3.4 159.3 44.7 132.5 232.0 3.8 26.1 192.9 49.8 10.3 162.9 13.2 185.3 2.0 2.3 212.5 245.5 49.2 38.2 73.4 134.6 20.4 18.6 14.7 131.5 46.5 89.4 18.9 15.5 38.7 77.7 140.9 95.7 21.0 129.5 144.8 VCAM1 CD106 ENSG00000162692 "Vascular cell adhesion molecule 1" P19320 1 100719742-100739045 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "lymphoid tissue: 389.3" "Cell type enhanced" "Detected in many" "Ductal cells: 142.6;Hepatic stellate cells: 94.9;Kupffer cells: 561.9;Proximal tubular cells: 188.4;Theca cells: 186.8" "Cancer enriched" "Detected in all" 8 "renal cancer: 89.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HHSteC: 164.7;HSkMC: 111.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000154, HPA034796, HPA069867" Enhanced Approved "Cell Junctions" NA NA 624000000 1300000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Cell Junctions" "CAB000154: , HPA034796: AB_2674333, HPA069867: AB_2686215" "unprognostic (2.96e-1)" "prognostic favorable (3.82e-4)" "unprognostic (1.31e-1)" "unprognostic (7.49e-3)" "unprognostic (1.04e-1)" "prognostic favorable (7.19e-5)" "unprognostic (1.60e-2)" "unprognostic (2.48e-1)" "unprognostic (1.18e-1)" "unprognostic (1.20e-1)" "unprognostic (3.95e-2)" "unprognostic (8.23e-2)" "unprognostic (1.80e-1)" "unprognostic (5.47e-2)" "unprognostic (1.68e-2)" "unprognostic (3.12e-2)" "unprognostic (2.55e-2)" 29.1 43.2 4.0 34.7 3.5 8.3 15.0 5.0 4.5 6.7 6.0 15.0 15.4 9.4 2.4 7.7 9.8 29.5 9.4 2.8 7.6 64.3 43.7 18.1 96.3 6.5 6.2 39.5 13.3 18.4 7.0 43.2 7.0 9.7 23.5 1.5 8.7 5.5 3.1 3.6 14.4 11.0 6.0 389.3 14.4 5.4 11.2 24.6 7.3 6.3 75.9 72.7 5.5 5.9 0.0 0.0 0.8 0.3 0.6 5.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.7 0.0 0.1 25.7 0.0 0.0 0.0 0.0 164.7 0.2 0.0 111.0 0.0 29.3 0.2 0.0 1.9 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.7 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.0 3.5 5.0 4.5 2.8 7.6 6.5 6.2 7.0 6.0 11.2 5.9 9.6 0.0 5.6 0.0 1.7 9.9 0.5 0.4 0.0 0.1 0.9 0.6 1.9 0.0 0.2 3.7 0.0 1.3 1.1 0.0 9.8 142.6 0.3 0.7 14.0 40.3 0.0 2.7 0.0 3.2 1.2 60.1 0.0 0.8 1.3 7.5 94.9 3.2 3.6 0.0 0.0 0.0 0.0 561.9 15.9 0.0 17.1 7.9 1.8 6.5 0.0 4.0 0.0 0.0 0.1 2.3 1.1 7.5 0.9 1.3 0.0 188.4 1.5 0.0 0.0 5.5 19.2 0.1 2.3 0.4 7.4 2.7 10.0 186.8 0.1 0.4 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 4.6 3.6 3.2 6.0 3.6 20.2 4.8 4.1 5.1 3.7 1.8 4.4 3.8 3.0 4.5 3.5 2.9 3.7 2.9 4.1 4.7 4.4 7.0 4.1 8.6 4.0 3.6 3.9 4.0 5.6 1.6 4.4 4.4 3.6 4.1 4.5 4.2 3.1 5.3 3.3 3.6 3.3 3.4 8.8 4.5 5.7 5.0 5.3 4.2 5.3 7.7 4.1 2.4 4.3 8.5 7.6 3.8 5.1 11.5 8.1 3.7 6.7 6.7 5.0 5.8 4.5 7.8 11.5 1.9 9.0 6.2 7.4 6.2 5.6 7.2 8.6 4.5 12.8 7.5 5.6 6.9 4.3 13.2 8.7 8.1 5.5 9.9 6.1 5.5 6.1 8.8 10.8 7.5 4.1 9.4 7.4 7.3 7.1 5.2 5.9 6.0 5.8 7.3 6.6 2.2 4.3 5.2 7.8 6.0 4.8 8.0 7.0 11.1 6.6 4.9 5.9 4.5 9.5 5.0 11.9 6.6 6.0 5.1 10.0 2.7 5.9 3.4 4.3 2.8 1.7 2.1 2.5 2.9 2.2 1.7 2.2 9.7 2.4 8.3 1.1 2.8 1.7 3.2 3.6 4.1 5.1 4.1 4.7 4.0 3.6 4.4 3.4 5.0 4.3 18.6 19.2 15.2 9.8 18.5 17.0 9.3 10.3 12.5 11.0 12.6 9.4 20.3 11.5 12.8 7.3 22.9 10.4 38.9 18.4 3.9 10.2 7.5 16.7 17.1 14.2 6.0 23.4 17.6 13.6 5.5 15.0 15.3 16.4 19.0 12.4 17.2 22.9 14.9 11.8 18.1 15.5 8.2 47.3 20.4 5.2 8.1 25.6 10.6 14.0 28.6 11.9 39.1 13.6 21.1 13.0 16.6 15.8 21.8 14.2 14.7 12.8 18.6 12.1 6.6 21.7 20.2 32.9 16.6 16.3 20.6 9.9 28.6 11.8 13.2 16.9 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 VPS13B "CHS1, COH1" ENSG00000132549 "Vacuolar protein sorting 13 homolog B" Q7Z7G8 8 99013266-99877580 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Disease variant, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 160.9;Excitatory neurons: 235.2;Inhibitory neurons: 253.2;Microglial cells: 204.2;Oligodendrocyte precursor cells: 217.1;Oligodendrocytes: 238.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043865 Approved "Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Cell Junctions" "HPA043865: AB_2678704" "unprognostic (4.23e-2)" "unprognostic (1.98e-2)" "unprognostic (1.02e-1)" "unprognostic (3.60e-3)" "unprognostic (5.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.94e-1)" "unprognostic (1.65e-3)" "unprognostic (8.60e-2)" "unprognostic (5.95e-2)" "unprognostic (6.52e-2)" "unprognostic (5.19e-2)" "unprognostic (1.59e-1)" "unprognostic (8.93e-3)" "unprognostic (2.90e-1)" 4.0 3.0 2.4 4.4 3.3 13.4 4.7 4.5 3.0 5.4 8.2 3.6 2.3 7.2 3.8 4.4 4.9 4.4 2.3 2.0 1.9 3.8 3.1 3.5 4.8 3.6 2.4 8.1 3.4 6.8 2.3 4.0 3.6 4.9 3.7 6.0 3.2 4.1 2.9 4.0 3.0 5.4 2.2 4.2 3.6 4.9 4.9 7.1 4.7 4.4 5.0 4.5 3.7 5.3 8.6 6.1 7.2 5.3 13.3 15.9 3.6 5.4 9.9 5.3 7.0 3.6 4.3 4.8 6.9 9.3 3.9 3.9 5.0 5.0 9.6 7.7 4.6 10.3 6.5 2.8 4.3 5.0 7.4 10.3 4.6 8.5 12.2 7.4 7.6 7.9 7.9 12.4 6.1 5.3 10.5 2.9 2.3 8.9 2.2 8.3 5.1 9.1 3.5 8.0 2.1 6.0 8.4 4.0 4.0 6.4 7.2 5.6 10.8 7.9 7.4 7.1 4.6 5.0 6.2 12.7 6.0 7.9 5.6 3.0 1.2 2.8 1.2 1.0 1.1 3.3 1.0 0.9 0.5 1.6 1.7 1.1 6.1 0.7 2.3 0.6 1.4 0.5 2.4 3.3 4.5 3.0 2.0 1.9 3.6 2.4 3.6 2.2 4.9 5.3 15.5 19.2 12.2 160.9 24.2 8.8 7.6 9.2 15.4 15.1 8.9 7.6 12.8 10.0 11.9 3.7 37.5 4.9 21.6 7.3 0.0 4.9 8.6 10.9 42.7 11.5 9.0 22.9 235.2 4.6 4.0 18.2 28.1 12.7 3.8 10.4 6.4 5.2 6.5 11.8 253.2 11.9 8.2 15.6 11.3 9.6 27.7 17.8 7.2 204.2 15.0 9.4 17.5 217.1 238.1 4.0 11.0 20.7 19.2 6.2 9.8 2.9 8.2 12.9 0.0 15.7 14.7 23.9 7.3 13.0 9.7 4.2 19.5 14.6 7.4 5.7 VPS36 "C13orf9, CGI-145, Eap45" ENSG00000136100 "Vacuolar protein sorting 36 homolog" Q86VN1 13 52412602-52450634 "Predicted intracellular proteins" "Protein transport, Transcription, Transcription regulation, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 265.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039734, HPA043947" Approved Supported "Vesicles,Lysosomes,Plasma membrane,Cell Junctions" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 31: Skin - Epidermis development" "Cluster 43: THP-1 - Innate immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Vesicles, Lysosomes" "Plasma membrane, Cell Junctions" "HPA039734: AB_2676652, HPA043947: AB_2678744" "unprognostic (2.43e-1)" "unprognostic (1.44e-1)" "unprognostic (2.80e-1)" "unprognostic (2.94e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-1)" "unprognostic (6.57e-2)" "unprognostic (7.84e-2)" "unprognostic (3.96e-3)" "unprognostic (1.19e-2)" "unprognostic (9.37e-2)" "unprognostic (5.57e-2)" "prognostic favorable (9.91e-6)" "unprognostic (6.47e-3)" "unprognostic (1.83e-1)" "unprognostic (1.94e-1)" "unprognostic (9.83e-2)" 17.1 15.1 10.1 16.8 11.5 8.6 26.1 14.0 16.3 20.0 9.6 24.5 27.6 18.7 12.2 23.7 16.8 16.6 24.0 11.8 10.1 25.4 23.6 19.9 19.5 12.4 11.0 17.9 17.9 23.3 11.0 25.0 12.8 21.8 27.5 43.1 25.2 18.3 23.4 51.1 27.7 20.7 9.9 24.1 18.1 4.0 12.1 22.3 22.5 26.2 20.7 18.9 21.3 12.1 7.3 11.8 20.4 13.5 21.1 29.3 17.8 16.7 12.5 16.1 9.6 14.3 22.9 25.5 8.6 23.8 10.6 20.1 16.6 19.7 18.0 19.3 16.0 30.2 18.7 12.8 25.3 40.2 31.4 20.5 37.9 11.2 18.0 18.0 16.6 33.6 22.7 21.8 31.8 9.6 30.4 40.6 19.5 29.0 6.3 31.0 11.9 15.9 28.7 18.9 10.4 22.0 11.9 27.3 25.9 24.0 15.9 67.1 26.3 10.3 12.6 10.3 19.1 16.3 22.0 26.8 10.6 28.4 24.7 15.6 14.6 12.3 12.3 16.3 19.8 15.3 13.5 15.4 15.6 13.0 12.2 13.1 3.6 21.6 22.7 16.3 16.0 13.7 10.1 11.5 14.0 16.3 11.8 10.1 12.4 11.0 12.8 9.9 12.1 12.1 54.2 83.3 51.5 41.1 49.9 42.8 48.9 57.6 62.0 132.2 51.6 72.8 80.8 38.6 47.7 33.1 120.9 60.2 83.4 62.6 68.4 35.4 1.2 28.0 45.9 55.7 49.8 31.1 57.0 29.3 43.0 46.6 36.7 37.0 44.3 44.9 38.2 54.0 43.8 52.2 54.6 64.1 40.7 44.0 29.1 3.7 49.7 47.1 28.4 36.5 60.8 39.8 59.8 44.7 40.7 29.8 63.0 52.3 55.0 65.4 77.4 78.5 33.2 265.8 46.0 52.7 76.1 15.3 25.9 83.5 58.2 38.2 48.2 40.6 58.6 45.4 VPS50 "CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L" ENSG00000004766 "VPS50 subunit of EARP/GARPII complex" Q96JG6 7 93232340-93361123 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026679 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Plasma membrane" "HPA026679: AB_1846135" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (3.12e-2)" "unprognostic (7.43e-2)" "unprognostic (4.97e-2)" "prognostic unfavorable (7.21e-5)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (1.37e-1)" "unprognostic (3.69e-1)" "unprognostic (5.17e-2)" "prognostic favorable (1.35e-6)" "unprognostic (2.08e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" 7.4 9.0 4.2 3.4 4.6 2.6 8.2 5.7 5.3 7.3 4.6 8.9 1.9 8.2 4.2 9.2 6.8 2.7 7.7 4.4 4.0 7.1 6.1 6.1 4.9 4.1 4.0 7.6 7.8 6.0 7.7 4.8 4.2 6.4 5.2 5.1 8.8 3.2 12.0 8.8 8.2 3.5 4.2 9.5 7.8 6.5 3.8 4.3 7.3 4.9 4.8 7.9 7.8 5.0 6.5 2.2 2.6 5.0 8.2 7.9 6.3 5.5 5.0 9.1 6.1 5.5 9.0 5.5 5.1 4.2 13.6 3.6 10.4 7.0 11.3 5.8 4.6 14.6 3.1 2.4 4.9 3.4 4.5 3.8 8.7 9.9 9.5 5.9 11.5 3.9 10.2 8.2 11.3 4.7 5.3 4.6 6.2 8.7 5.9 3.5 6.3 8.1 5.1 2.9 3.7 7.8 4.8 13.5 4.4 7.5 6.3 2.8 5.8 12.4 4.4 16.3 4.5 3.3 8.0 9.1 6.9 6.1 6.8 3.1 3.2 2.1 2.6 3.5 4.6 2.4 2.7 2.7 4.5 2.4 2.0 2.5 1.1 1.4 2.5 2.8 2.9 2.0 4.2 4.6 5.7 5.3 4.4 4.0 4.1 4.0 4.2 4.2 3.8 5.0 10.9 12.8 11.3 0.0 13.5 0.0 3.4 0.0 6.8 14.1 11.7 6.3 0.0 2.8 5.0 5.5 16.7 7.5 11.0 5.5 3.9 6.2 27.9 7.6 10.8 7.9 2.4 10.8 0.0 5.5 11.7 6.4 11.2 8.2 7.6 12.6 9.7 6.1 10.7 10.1 0.0 7.1 0.0 13.7 0.0 14.2 9.0 10.0 0.0 0.0 9.4 10.3 6.2 0.0 0.0 6.9 9.4 7.2 10.2 2.7 6.1 8.3 5.8 14.3 6.6 11.2 6.3 18.1 12.8 7.9 0.0 9.4 8.5 13.9 5.1 2.8 VPS8 "FLJ32099, KIAA0804" ENSG00000156931 "VPS8 subunit of CORVET complex" Q8N3P4 3 184812143-185052614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 154.1;Granulosa cells: 124.3;Inhibitory neurons: 132.2;Oligodendrocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036871 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA036871: AB_10672103" "unprognostic (4.36e-2)" "unprognostic (3.97e-3)" "unprognostic (1.53e-1)" "unprognostic (7.95e-2)" "unprognostic (5.11e-2)" "unprognostic (4.43e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (3.21e-2)" "unprognostic (5.98e-3)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (3.15e-1)" "unprognostic (2.56e-1)" "unprognostic (8.10e-3)" "unprognostic (4.97e-2)" 10.9 9.6 18.7 10.0 22.1 23.2 10.6 24.2 24.0 12.7 29.1 11.4 8.3 12.3 16.3 10.1 9.0 11.1 19.6 20.4 23.6 10.6 8.5 10.7 10.5 25.1 21.4 14.3 8.9 15.8 16.3 12.1 26.3 10.9 14.7 16.4 7.9 10.1 28.6 12.9 9.3 12.9 17.1 13.3 13.0 16.9 26.1 11.6 14.9 15.3 10.7 10.4 10.3 36.4 18.0 10.7 15.9 15.9 32.5 28.8 10.6 17.7 18.8 12.3 17.0 13.6 9.0 19.1 29.3 26.9 50.4 20.8 17.3 21.0 23.6 34.8 15.4 20.4 13.0 8.1 20.0 14.3 27.0 20.6 19.4 17.6 17.5 22.6 31.4 17.7 10.9 13.5 22.7 12.8 11.6 8.5 10.5 18.4 10.1 14.1 30.6 15.0 12.2 30.8 16.2 10.6 19.9 20.8 15.6 23.6 33.2 7.5 27.9 18.8 10.5 19.6 15.3 16.5 21.5 25.9 21.6 17.7 15.5 19.0 6.6 22.9 5.0 5.2 4.9 4.4 5.4 5.2 8.1 5.5 8.0 5.4 23.9 5.7 6.6 2.3 4.8 4.3 18.7 22.1 24.2 24.0 20.4 23.6 25.1 21.4 26.3 17.1 26.1 36.4 11.8 12.8 11.5 66.3 17.9 10.5 9.2 8.3 11.4 24.5 8.7 8.3 24.6 11.5 9.7 9.2 18.8 12.8 10.8 17.3 7.9 7.7 22.2 11.0 17.5 12.8 18.0 11.6 154.1 4.6 6.7 14.7 21.9 14.3 2.5 124.3 12.5 7.7 20.2 11.8 132.2 16.6 12.2 19.1 16.7 16.5 10.5 21.2 10.6 89.9 32.0 10.1 32.0 86.5 149.2 6.4 12.7 12.8 14.4 9.4 9.2 8.8 14.4 17.3 6.6 13.0 10.0 94.3 27.8 15.8 16.1 7.7 17.8 11.8 13.2 13.0 VSIG4 "CRIg, Z39IG" ENSG00000155659 "V-set and immunoglobulin domain containing 4" Q9Y279 X 66021738-66040125 "Plasma proteins, Predicted membrane proteins" "Complement alternate pathway, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 166.0" "Group enriched" "Detected in many" 5 "Hofbauer cells: 989.8;Kupffer cells: 590.9;Macrophages: 328.4" "Cancer enriched" "Detected in all" 5 "glioma: 88.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 27 "classical monocyte: 18.7;intermediate monocyte: 11.1;myeloid DC: 17.8" "Group enriched" "Detected in many" 31 "dendritic cells: 17.8;monocytes: 18.7" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA003903, CAB026000" Enhanced Uncertain "Nucleoli,Plasma membrane,Cytosol" NA NA 59000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 19: Lung - Lung function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" Nucleoli "CAB026000: , HPA003903: AB_1858776" "unprognostic (6.87e-3)" "unprognostic (4.79e-2)" "prognostic unfavorable (1.34e-4)" "unprognostic (3.19e-1)" "unprognostic (1.30e-2)" "unprognostic (1.53e-2)" "unprognostic (9.37e-3)" "unprognostic (1.24e-1)" "unprognostic (3.10e-1)" "unprognostic (1.37e-3)" "unprognostic (1.06e-1)" "unprognostic (2.77e-1)" "prognostic unfavorable (1.95e-6)" "unprognostic (3.70e-2)" "unprognostic (5.45e-2)" "unprognostic (3.37e-2)" "unprognostic (3.47e-2)" 137.1 68.8 17.9 44.2 18.8 7.8 44.2 17.0 36.6 14.1 21.5 40.9 22.5 15.5 5.3 15.4 66.8 39.6 30.0 18.2 18.3 17.9 51.0 166.0 27.8 25.1 23.6 12.9 14.3 6.8 7.0 139.6 25.8 10.6 31.7 2.2 24.5 9.3 8.2 10.8 43.9 108.3 18.9 69.3 22.9 7.3 37.6 5.4 12.3 12.5 1.8 61.5 11.6 26.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 18.7 0.1 0.0 11.1 0.0 0.0 0.0 0.2 17.8 0.1 0.0 0.0 0.5 0.0 0.4 0.1 0.0 5.6 17.9 18.8 17.0 36.6 18.2 18.3 25.1 23.6 25.8 18.9 37.6 26.7 1.3 3.2 16.1 0.0 1.2 2.3 0.3 0.0 0.0 0.0 2.6 0.5 1.8 7.2 3.1 0.0 0.0 5.3 0.3 0.0 0.0 0.1 7.9 0.0 0.0 10.4 0.0 0.0 0.0 0.0 4.9 2.7 0.0 0.0 3.8 0.0 5.0 3.2 989.8 0.0 0.0 0.0 0.0 590.9 111.8 16.6 1.5 328.4 3.6 12.2 1.5 0.5 0.0 0.5 0.0 0.0 0.1 0.4 0.3 0.3 0.0 0.1 4.4 0.0 6.6 0.6 2.0 0.3 0.9 0.5 1.7 12.3 1.5 0.0 0.0 0.2 VTCN1 "B7-H4, B7H4, B7S1, B7x, FLJ22418" ENSG00000134258 "V-set domain containing T cell activation inhibitor 1" Q7Z7D3 1 117143587-117210960 "Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 100.9;fallopian tube: 32.7;pancreas: 30.1" "Cell type enhanced" "Detected in some" "Breast glandular cells: 62.3;Collecting duct cells: 55.2;Ductal cells: 83.6;Endometrial ciliated cells: 42.7;Exocrine glandular cells: 34.2;Glandular and luminal cells: 79.1" "Group enriched" "Detected in many" 6 "breast cancer: 55.8;endometrial cancer: 45.2;ovarian cancer: 49.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SK-BR-3: 244.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA054200 Approved Approved "Plasma membrane,Cell Junctions,Focal adhesion sites" No NA "Cluster 5: Breast - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions, Focal adhesion sites" "HPA054200: AB_2682415" "unprognostic (4.13e-1)" "unprognostic (1.71e-3)" "unprognostic (2.95e-1)" "unprognostic (3.44e-2)" "unprognostic (1.71e-3)" "unprognostic (2.56e-1)" "unprognostic (7.94e-2)" "unprognostic (4.86e-2)" "unprognostic (3.53e-1)" "unprognostic (1.17e-2)" "unprognostic (4.54e-2)" "unprognostic (5.47e-2)" "unprognostic (1.50e-2)" "unprognostic (1.06e-1)" "unprognostic (2.42e-1)" "unprognostic (3.07e-1)" "unprognostic (1.45e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 100.9 0.0 0.0 15.3 0.0 0.0 0.4 4.5 5.0 0.4 32.7 5.0 0.2 0.0 0.0 17.3 1.1 0.7 0.0 0.0 0.0 0.1 30.1 0.0 0.1 0.8 0.0 3.0 0.0 0.0 22.1 7.8 0.2 2.8 0.0 0.1 0.0 0.0 3.6 1.1 0.1 0.1 0.0 0.0 0.0 3.2 0.1 0.0 1.0 0.1 1.7 0.0 0.0 0.0 44.8 0.0 0.0 0.0 0.0 0.0 0.9 0.0 7.5 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.9 0.1 0.0 0.1 0.0 0.1 0.1 0.2 0.1 4.2 0.1 1.2 0.0 0.0 244.8 0.1 29.9 14.2 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.0 2.5 6.9 0.0 0.0 62.3 18.4 1.1 0.0 22.6 55.2 0.0 3.4 1.1 0.0 0.0 83.6 2.5 42.7 4.4 0.6 0.0 0.0 0.8 34.2 1.4 0.4 0.0 79.1 0.0 0.0 0.0 0.0 0.6 0.0 0.6 0.0 6.1 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.3 11.3 0.0 0.0 0.0 1.6 0.0 0.3 8.3 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.0 3.0 0.5 0.0 0.0 4.8 VWA5B1 FLJ32784 ENSG00000158816 "Von Willebrand factor A domain containing 5B1" Q5TIE3 1 20290919-20354894 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.3;choroid plexus: 19.1" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 10.9;Inhibitory neurons: 1.8;Late spermatids: 9.0" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 10 "SCLC-21H: 1.2" "Low region specificity" "Detected in many" "HPA027496, HPA028405, HPA064829" Enhanced Approved "Plasma membrane,Mitochondria,Cytosol" "Secreted in male reproductive system" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" Mitochondria "Plasma membrane, Cytosol" "HPA027496: AB_10599853, HPA028405: AB_10600992, HPA064829: AB_2685363" "unprognostic (2.34e-1)" "unprognostic (2.91e-1)" "unprognostic (7.78e-2)" "unprognostic (1.16e-2)" "unprognostic (4.73e-2)" "unprognostic (1.21e-2)" "unprognostic (1.09e-1)" "unprognostic (1.86e-2)" "unprognostic (4.39e-2)" "unprognostic (1.73e-1)" "unprognostic (5.41e-4)" "unprognostic (7.43e-4)" "unprognostic (1.82e-2)" "unprognostic (3.33e-2)" "unprognostic (1.03e-1)" 0.0 0.4 0.8 0.1 0.9 0.0 0.0 0.1 0.1 0.0 19.1 0.0 0.0 0.0 1.3 0.0 0.3 0.2 0.0 1.1 2.9 1.3 0.0 0.1 0.1 3.7 6.3 0.0 0.0 1.1 2.9 0.1 5.1 0.0 0.0 0.1 1.7 0.3 0.0 0.0 0.0 0.0 1.5 0.0 0.0 3.2 3.0 0.0 0.2 0.4 0.0 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.9 0.1 0.1 1.1 2.9 3.7 6.3 5.1 1.5 3.0 0.7 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.9 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 9.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;Gastric mucus-secreting cells: 8.2;Proximal enterocytes: 5.0;Proximal tubular cells: 2.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 2.9;hypothalamus: 8.2;medulla oblongata: 5.9;pons: 5.5;thalamus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;HMC-1: 1.3;Karpas-707: 1.1;U-266/84: 1.6" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 9200 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" 0.4 0.3 0.5 0.1 0.3 0.0 0.7 0.1 2.9 0.8 0.0 1.3 1.0 4.6 0.0 0.4 7.2 0.7 5.2 0.8 8.2 5.7 1.4 1.4 0.1 5.9 1.0 0.5 2.6 1.7 21.3 0.0 5.5 0.8 0.4 0.2 1.4 1.3 6.6 0.8 2.3 0.0 0.0 0.5 3.0 0.7 7.5 0.0 1.8 0.0 0.1 0.6 0.7 1.0 0.8 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.1 2.9 0.8 8.2 5.9 1.0 5.5 0.0 7.5 1.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 0.5 1.2 0.5 0.1 0.3 0.8 0.0 0.3 1.8 0.0 0.0 0.2 1.4 1.9 0.6 0.0 1.5 0.1 0.1 4.2 0.0 1.5 0.5 0.0 0.1 8.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.4 0.3 5.0 2.4 1.6 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.5 0.4 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WASF2 "SCAR2, WAVE2" ENSG00000158195 "WASP family member 2" Q9Y6W5 1 27404230-27490167 "Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022632, HPA045288" Enhanced Approved "Plasma membrane,Cytosol" NA NA 84000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "CAB022632: , HPA045288: AB_2679287" "unprognostic (9.58e-2)" "unprognostic (8.93e-2)" "unprognostic (6.28e-2)" "unprognostic (1.02e-1)" "unprognostic (4.40e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (5.29e-8)" "unprognostic (3.94e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (7.60e-3)" "unprognostic (1.10e-1)" "unprognostic (9.15e-3)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (8.26e-2)" 55.2 34.1 37.9 44.1 48.1 59.8 45.8 42.3 36.3 41.3 29.5 49.4 27.5 53.8 21.6 89.8 46.3 31.1 32.9 33.4 39.5 28.4 14.9 45.7 48.1 58.9 49.0 63.5 35.2 31.0 17.0 52.3 53.6 33.1 39.3 9.1 38.3 41.9 18.4 56.7 42.3 51.9 48.2 47.6 40.3 36.8 48.4 54.6 35.5 27.8 52.3 47.8 39.9 50.6 75.4 35.3 80.3 73.4 57.1 74.3 46.5 59.9 55.5 64.7 57.9 30.8 79.2 52.1 56.6 94.4 44.1 58.8 65.5 98.4 77.1 73.3 41.1 113.5 60.5 36.7 76.9 91.9 62.8 68.5 105.1 70.7 130.8 70.0 82.3 56.8 92.3 26.3 89.0 27.1 68.7 42.1 64.9 38.3 53.7 141.8 98.5 53.3 46.3 42.0 39.9 43.8 104.6 46.3 78.3 48.6 38.7 55.1 109.1 53.4 54.8 112.1 47.8 53.6 76.0 67.7 63.0 111.2 61.3 50.0 65.4 54.7 33.3 79.8 27.2 37.8 26.3 23.5 41.7 46.6 26.9 21.2 100.7 24.4 112.7 60.5 28.8 58.6 37.9 48.1 42.3 36.3 33.4 39.5 58.9 49.0 53.6 48.2 48.4 50.6 243.0 67.3 57.5 58.1 112.7 148.1 221.8 245.9 104.2 24.4 143.0 201.9 39.6 75.8 144.1 90.1 14.6 219.2 145.1 147.0 62.6 111.0 51.4 86.6 167.7 194.8 108.5 195.1 19.1 101.7 118.9 157.9 85.1 174.2 58.9 77.7 163.5 48.4 151.2 20.2 12.8 101.9 93.6 250.4 129.2 75.9 165.0 162.7 76.5 93.7 207.6 61.2 142.2 29.1 67.1 164.9 131.8 182.4 74.2 281.7 139.1 50.7 104.4 19.2 138.1 206.1 180.6 120.7 118.1 216.3 194.5 143.5 104.5 79.3 120.3 372.5 WBP4 "FBP21, MGC117310" ENSG00000120688 "WW domain binding protein 4" O75554 13 41061509-41084006 "Predicted intracellular proteins" "mRNA processing, mRNA splicing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038965, HPA058738" Approved Supported "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 80: Striated muscle - Unknown function" "Cluster 36: HEL - Hemostasis" "Cluster 39: Non-specific - Basic cellular processes" Nucleoplasm "Vesicles, Plasma membrane" "HPA038965: AB_10672836, HPA058738: AB_2683803" "unprognostic (2.56e-1)" "unprognostic (3.69e-3)" "unprognostic (1.75e-1)" "unprognostic (1.99e-2)" "unprognostic (9.30e-2)" "unprognostic (1.76e-3)" "unprognostic (1.54e-2)" "unprognostic (2.13e-2)" "unprognostic (1.34e-2)" "unprognostic (2.05e-2)" "unprognostic (3.71e-3)" "unprognostic (2.97e-1)" "unprognostic (2.66e-2)" "unprognostic (8.52e-2)" "unprognostic (7.65e-3)" "prognostic favorable (2.89e-4)" "unprognostic (2.52e-1)" 17.5 16.0 16.1 9.8 16.8 15.6 13.4 16.5 23.9 12.0 13.2 13.2 11.2 18.5 16.0 11.2 11.1 9.3 23.1 16.1 18.1 12.3 16.3 10.4 11.8 16.3 16.6 13.2 8.7 12.4 8.2 11.5 16.4 14.0 9.1 16.5 8.1 14.7 41.0 11.3 11.5 14.8 15.7 9.8 9.3 12.2 16.5 14.7 11.2 29.8 11.6 11.3 11.0 18.6 15.0 9.8 26.7 17.3 17.1 25.9 16.2 33.3 23.4 25.9 19.7 15.5 15.7 21.4 13.0 23.6 31.2 20.6 10.2 16.7 33.0 22.3 14.3 30.2 10.0 16.0 26.3 19.1 18.8 21.3 25.0 18.8 26.5 21.1 22.0 20.3 16.4 9.1 27.5 12.6 27.3 20.6 16.3 23.2 8.0 25.3 16.5 8.4 23.6 14.6 6.1 14.7 10.6 11.3 16.1 21.5 9.4 29.3 19.3 16.0 14.7 22.2 19.5 6.0 7.0 14.7 19.7 13.7 22.2 19.2 13.0 12.4 10.6 12.0 9.7 14.2 13.6 11.5 11.0 12.6 14.4 14.3 27.3 12.5 21.8 18.5 14.4 6.1 16.1 16.8 16.5 23.9 16.1 18.1 16.3 16.6 16.4 15.7 16.5 18.6 42.4 51.3 29.3 21.2 23.9 54.4 60.3 54.8 33.0 46.8 33.5 37.5 110.0 40.0 32.5 25.8 33.3 55.6 23.0 32.3 76.3 52.3 11.9 32.9 58.4 46.9 37.8 111.7 17.0 42.0 61.1 52.2 15.8 44.5 45.7 27.5 38.2 63.1 40.9 45.4 16.6 28.1 18.3 26.7 47.1 9.7 47.8 33.0 32.0 10.3 60.4 63.8 28.8 17.1 33.3 50.3 33.2 52.6 16.8 60.9 33.8 70.6 23.6 49.2 26.3 55.3 66.7 87.5 103.9 29.7 44.9 49.9 22.3 31.9 27.6 40.9 WDFY3 "ALFY, KIAA0993, ZFYVE25" ENSG00000163625 "WD repeat and FYVE domain containing 3" Q8IZQ1 4 84669597-84966690 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Autophagy "Developmental protein" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 44.9" "Group enriched" "Detected in many" 5 "Astrocytes: 241.0;Excitatory neurons: 231.0;Inhibitory neurons: 248.7;Microglial cells: 209.9;Oligodendrocyte precursor cells: 262.9;Oligodendrocytes: 440.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "TIME: 57.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042734, HPA048572" Approved Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Nucleoli, Plasma membrane" "HPA042734: AB_2678135, HPA048572: AB_2680447" "unprognostic (7.14e-2)" "unprognostic (6.02e-2)" "unprognostic (7.68e-2)" "unprognostic (1.60e-1)" "unprognostic (1.84e-2)" "unprognostic (2.48e-1)" "unprognostic (2.86e-2)" "unprognostic (3.36e-1)" "unprognostic (1.01e-1)" "unprognostic (4.33e-2)" "unprognostic (3.36e-1)" "unprognostic (7.12e-2)" "prognostic favorable (3.64e-5)" "prognostic unfavorable (9.35e-4)" "unprognostic (2.79e-1)" "unprognostic (4.41e-2)" "unprognostic (4.95e-2)" 8.6 8.6 14.8 7.6 31.7 14.4 8.7 26.8 22.9 8.5 4.7 5.7 3.6 8.2 6.4 7.4 8.2 8.8 5.7 16.3 15.6 20.1 5.6 7.4 2.6 30.6 30.4 13.6 9.0 16.3 6.5 11.8 28.7 8.6 5.6 26.2 7.2 7.4 5.9 10.8 4.7 8.5 21.7 7.8 5.6 8.1 25.6 3.4 11.7 13.2 2.3 8.7 5.7 44.9 11.9 7.8 14.3 7.9 24.8 19.3 9.0 11.2 11.8 11.5 10.3 9.1 9.6 0.0 11.3 18.8 12.3 5.9 15.4 12.3 14.6 7.9 4.9 7.5 9.0 5.5 9.4 5.9 13.7 14.2 10.9 15.0 15.1 13.9 37.1 6.0 7.5 35.3 21.4 8.5 5.7 1.4 7.4 11.4 4.0 8.4 11.4 1.8 19.6 15.6 16.8 7.8 13.8 15.1 7.5 13.5 7.9 14.4 57.0 15.1 14.9 8.5 14.1 0.1 0.0 0.0 10.2 5.0 16.9 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.1 14.8 31.7 26.8 22.9 16.3 15.6 30.6 30.4 28.7 21.7 25.6 44.9 28.5 19.2 12.9 241.0 1.0 14.7 9.1 12.4 11.4 46.6 13.8 11.3 18.2 20.0 14.7 16.5 35.5 11.8 0.5 6.5 1.9 8.6 6.7 27.1 27.8 20.1 9.1 1.3 231.0 7.3 6.9 19.5 15.3 43.4 0.0 31.0 17.9 8.1 20.5 28.6 248.7 7.8 20.3 43.1 14.1 10.1 18.3 29.9 7.2 209.9 19.7 28.7 0.0 262.9 440.4 10.7 6.5 24.5 0.2 13.6 4.8 18.4 15.5 41.9 26.3 30.0 22.8 11.4 7.3 14.1 16.1 14.5 1.8 15.0 6.7 13.6 WDPCP "BBS15, C2orf86, CPLANE5, fritz, hFrtz" ENSG00000143951 "WD repeat containing planar cell polarity effector" O95876 2 63119559-63827843 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Bardet-Biedl syndrome, Ciliopathy, Disease variant, Mental retardation, Obesity" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 18.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 169.9;Alveolar cells type 2: 128.0;Astrocytes: 124.7;Excitatory neurons: 261.4;Inhibitory neurons: 240.9;Oligodendrocyte precursor cells: 136.2;Oligodendrocytes: 296.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044144 Uncertain Approved "Cell Junctions" Yes No "Cluster 41: Basophils - Cellular respiration" "Cluster 6: Brain - Smell perception" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "HPA044144: AB_10969458" "unprognostic (3.36e-1)" "unprognostic (3.22e-2)" "unprognostic (1.95e-1)" "unprognostic (7.07e-2)" "unprognostic (2.95e-1)" "unprognostic (6.88e-2)" "unprognostic (1.71e-1)" "unprognostic (1.59e-3)" "unprognostic (7.22e-2)" "unprognostic (6.48e-2)" "unprognostic (1.93e-1)" "unprognostic (4.87e-2)" "unprognostic (2.34e-3)" "unprognostic (6.02e-2)" "unprognostic (1.97e-1)" "unprognostic (2.25e-3)" "unprognostic (2.00e-1)" 4.7 3.5 11.3 2.5 11.7 8.2 3.2 17.7 15.7 2.5 6.5 1.6 1.8 3.9 4.0 2.0 4.2 2.8 4.9 10.4 6.9 3.6 2.4 2.5 3.3 6.4 5.4 4.6 1.5 2.9 1.9 2.6 8.4 2.6 1.8 12.2 2.2 2.1 5.3 3.4 1.7 3.0 3.2 3.3 3.3 5.1 6.3 3.6 3.5 2.9 2.7 1.8 1.1 18.6 5.2 4.6 3.3 4.0 3.7 4.6 3.0 4.3 2.2 2.8 2.3 3.3 2.6 5.8 3.5 2.9 3.3 3.4 2.3 2.8 3.3 5.7 3.8 6.1 3.5 2.8 2.5 5.0 4.1 2.3 1.9 2.9 1.9 3.7 2.9 6.7 2.3 5.7 2.9 5.3 5.8 5.1 3.9 2.7 1.7 6.2 4.3 5.0 1.9 2.5 5.2 5.2 3.7 4.4 5.3 4.7 3.8 3.9 4.7 4.6 7.2 4.0 3.6 5.3 3.6 10.3 5.2 5.3 5.3 6.6 2.8 1.5 1.9 1.5 3.7 1.8 1.7 2.6 2.3 3.1 2.3 3.6 1.9 3.8 1.3 2.7 1.5 1.1 11.3 11.7 17.7 15.7 10.4 6.9 6.4 5.4 8.4 3.2 6.3 18.6 6.0 169.9 128.0 124.7 8.0 4.1 3.2 4.3 2.8 16.1 4.4 3.2 10.1 7.2 59.6 1.8 22.9 2.5 5.5 0.8 1.9 2.6 46.7 17.9 6.2 14.4 0.0 7.8 261.4 2.2 2.6 13.5 6.6 3.7 65.0 7.4 5.0 1.8 4.0 11.8 240.9 1.3 4.1 3.0 4.4 17.5 4.4 8.4 5.4 103.0 3.8 7.5 6.2 136.2 296.3 1.8 1.6 3.8 5.1 1.5 0.5 4.5 98.8 27.4 0.0 8.6 5.7 16.1 9.5 2.3 3.4 1.9 9.4 4.0 1.1 1.7 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 WDR12 "FLJ10881, YTM1" ENSG00000138442 "WD repeat domain 12" Q9GZL7 2 202874261-203014798 "Plasma proteins, Predicted intracellular proteins" "Ribosome biogenesis, rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036389 Uncertain Approved "Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" Nucleoli "HPA036389: AB_10670716" "unprognostic (1.08e-2)" "unprognostic (3.59e-1)" "unprognostic (8.17e-2)" "unprognostic (3.59e-3)" "unprognostic (1.24e-2)" "unprognostic (9.40e-3)" "prognostic unfavorable (2.57e-6)" "unprognostic (1.52e-1)" "unprognostic (6.14e-2)" "unprognostic (4.78e-2)" "unprognostic (4.58e-2)" "unprognostic (1.50e-1)" "unprognostic (1.69e-1)" "unprognostic (5.21e-2)" "unprognostic (2.66e-1)" "unprognostic (9.69e-3)" "unprognostic (4.48e-2)" 2.6 3.6 2.1 2.7 2.3 3.6 3.6 2.3 3.2 2.5 1.4 3.0 4.1 3.2 3.2 3.2 3.1 2.3 4.0 2.2 2.9 5.2 4.2 1.7 3.3 2.5 2.1 3.2 2.2 3.5 1.9 2.7 2.7 2.2 4.0 2.6 1.9 2.3 4.8 3.6 2.9 3.4 1.5 2.1 2.3 3.5 2.8 3.2 3.2 6.0 3.7 4.1 2.3 2.5 5.3 5.8 6.4 12.5 12.3 10.4 11.4 7.6 6.6 10.1 9.8 14.8 7.5 10.2 7.2 6.6 8.5 6.6 18.2 13.3 16.0 4.6 11.1 17.0 9.0 17.7 8.0 22.1 9.9 9.5 9.4 12.0 23.6 6.4 10.8 10.2 26.7 5.9 11.3 6.5 14.8 13.3 14.9 7.3 14.3 11.1 9.7 16.1 11.2 6.5 11.4 9.8 6.5 8.2 9.8 11.0 4.7 14.1 8.3 8.3 6.9 7.4 8.4 8.0 12.8 16.3 8.7 15.3 8.8 1.3 1.6 0.6 1.4 1.7 2.0 1.9 1.3 1.4 2.1 1.9 1.7 1.7 0.6 1.3 1.7 2.4 1.6 1.1 2.1 2.3 2.3 3.2 2.2 2.9 2.5 2.1 2.7 1.5 2.8 2.5 10.1 9.6 16.9 12.1 13.6 20.5 21.4 24.4 13.1 10.2 8.4 9.1 27.9 7.2 19.1 5.5 2.1 25.3 7.9 7.8 15.6 18.0 14.3 14.7 25.3 12.6 5.4 22.1 19.2 10.6 34.9 16.5 9.7 13.3 15.2 15.8 8.2 15.0 18.0 15.2 20.3 10.6 24.4 7.2 6.0 8.9 17.1 9.2 1.8 12.2 13.7 6.4 5.2 10.6 9.9 14.2 6.6 15.4 9.3 17.3 13.9 38.1 15.7 8.3 13.1 20.1 41.9 43.0 32.3 18.2 17.3 21.5 10.7 21.0 19.2 17.0 WDR13 ENSG00000101940 "WD repeat domain 13" Q9H1Z4 X 48590042-48608869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000913 Supported Supported "Nucleoplasm,Plasma membrane,Centriolar satellite" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane, Centriolar satellite" "HPA000913: AB_1858795" "unprognostic (5.03e-2)" "unprognostic (6.53e-3)" "unprognostic (3.65e-3)" "unprognostic (2.10e-3)" "unprognostic (3.50e-1)" "unprognostic (1.54e-3)" "unprognostic (3.54e-2)" "unprognostic (6.76e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-1)" "unprognostic (1.58e-2)" "unprognostic (1.33e-1)" "unprognostic (2.82e-1)" "unprognostic (2.99e-1)" "unprognostic (1.66e-1)" "unprognostic (2.65e-1)" "unprognostic (4.32e-2)" 67.2 76.7 84.2 27.7 81.1 34.6 63.8 68.2 95.2 71.6 85.0 71.6 43.8 71.5 73.7 54.6 67.1 33.4 150.3 85.7 70.4 91.9 106.3 60.8 23.4 73.0 70.2 93.1 189.2 36.9 80.1 29.5 70.5 67.5 26.3 28.2 75.7 45.3 105.2 56.9 54.4 37.5 69.4 58.6 76.6 22.9 74.5 18.7 64.8 83.0 19.6 59.5 56.3 78.5 41.6 59.4 29.3 90.8 39.3 57.4 22.4 28.1 50.7 31.9 29.0 35.5 64.8 28.7 26.3 57.8 25.7 35.0 14.6 61.6 11.3 34.2 26.2 19.7 72.2 65.3 89.3 17.1 51.4 54.7 86.4 45.3 82.7 55.6 44.4 16.3 19.8 35.5 44.9 59.4 23.7 29.9 21.2 18.0 46.6 22.4 31.0 52.3 56.7 32.6 33.9 41.9 31.8 65.2 66.9 20.4 41.9 32.6 74.0 33.0 48.8 52.8 27.5 41.0 16.6 11.0 48.9 25.3 46.5 75.5 42.4 24.7 20.9 47.4 16.7 32.7 21.8 19.9 39.1 25.0 17.4 19.6 29.9 33.0 57.2 24.6 27.0 31.1 84.2 81.1 68.2 95.2 85.7 70.4 73.0 70.2 70.5 69.4 74.5 78.5 61.1 44.8 41.7 19.9 22.3 35.1 72.8 69.1 37.5 45.5 39.2 35.8 79.7 68.6 49.9 20.2 54.2 44.2 19.9 75.5 103.7 89.0 6.1 75.9 36.1 54.0 50.4 31.2 7.8 119.2 34.5 50.5 62.2 53.0 30.4 46.2 65.3 50.2 42.6 33.7 6.6 58.3 50.8 35.4 30.6 20.8 51.6 34.9 58.7 15.0 42.1 68.9 22.6 7.1 14.0 96.8 75.0 43.2 28.3 48.3 90.2 140.7 74.3 55.6 46.0 51.2 59.6 11.2 21.0 29.7 29.8 70.7 21.4 56.2 59.8 65.8 WDR53 "MGC12928, MGC64882" ENSG00000185798 "WD repeat domain 53" Q7Z5U6 3 196554177-196568674 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 74.2" "Group enriched" "Detected in many" 9 "Early spermatids: 313.9;Late spermatids: 118.8;Spermatocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016420 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA016420: AB_1858812" "unprognostic (3.29e-2)" "unprognostic (4.24e-3)" "unprognostic (9.89e-2)" "unprognostic (2.29e-3)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.57e-1)" "unprognostic (2.10e-3)" "unprognostic (4.48e-3)" "unprognostic (8.01e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" 7.8 7.4 9.4 6.9 10.3 14.7 9.0 10.3 12.1 7.7 9.7 8.1 4.3 8.1 11.0 9.0 7.1 6.3 8.1 9.5 10.0 8.8 10.0 6.9 10.6 9.6 9.7 7.0 5.9 10.0 6.7 6.3 11.2 7.2 7.1 8.9 7.0 6.1 13.0 11.9 7.9 7.4 9.4 10.8 7.2 74.2 9.8 12.1 7.1 12.6 11.9 7.2 7.6 11.3 39.4 8.5 14.6 13.6 15.0 13.2 23.8 20.1 16.2 23.0 21.7 22.8 20.2 18.9 66.4 13.0 21.2 22.3 18.9 18.4 28.8 30.0 16.3 19.4 21.2 14.6 18.5 26.9 14.3 10.7 25.9 20.6 22.2 11.4 18.7 23.6 18.8 34.5 17.7 36.4 22.5 27.5 19.5 25.7 24.4 26.5 25.3 40.5 12.8 13.4 15.0 15.2 15.0 20.8 32.2 19.8 53.0 24.2 17.2 18.9 18.0 21.5 40.6 29.5 63.8 56.6 12.7 34.2 19.4 13.1 5.5 15.7 8.8 4.7 14.1 7.8 12.2 8.5 4.7 7.5 10.2 6.1 4.7 7.4 7.8 6.2 16.5 5.0 9.4 10.3 10.3 12.1 9.5 10.0 9.6 9.7 11.2 9.4 9.8 11.3 3.9 0.0 2.8 6.8 3.8 4.2 3.2 8.1 2.8 3.7 3.4 3.4 5.6 2.8 5.8 3.7 0.0 5.7 3.5 1.7 5.9 5.0 313.9 3.3 3.5 4.7 0.0 7.4 5.5 4.2 6.1 3.9 0.5 2.7 9.5 3.2 3.9 2.5 4.3 3.3 4.8 1.6 10.2 3.8 3.0 118.8 5.0 3.9 5.4 10.3 7.3 4.0 4.1 6.0 7.1 3.7 1.9 3.4 3.7 2.9 1.5 5.0 3.1 2.8 19.7 4.0 5.5 135.6 13.9 3.5 4.7 4.7 6.3 4.1 2.7 2.6 WDR6 ENSG00000178252 "WD repeat domain 6" Q9NNW5 3 49007062-49015953 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042622 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA042622: AB_10966784" "unprognostic (2.41e-2)" "unprognostic (2.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.26e-2)" "unprognostic (4.80e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.97e-6)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-3)" "unprognostic (1.94e-2)" "prognostic favorable (4.52e-5)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.61e-2)" 67.5 148.8 108.7 51.9 106.3 41.8 69.8 104.9 124.5 153.1 120.1 130.1 66.5 122.8 83.1 65.1 129.8 59.7 82.7 105.8 116.3 113.7 97.7 77.8 61.2 105.1 112.8 205.9 136.7 91.0 207.4 46.1 108.1 159.3 50.9 49.4 99.2 74.1 71.4 63.7 105.4 68.1 102.0 112.9 93.3 61.2 120.9 54.7 178.2 37.8 53.5 118.8 90.5 107.2 61.4 82.4 133.7 113.7 87.8 71.1 90.1 89.4 73.1 98.7 79.4 73.9 86.2 98.3 55.5 143.2 75.8 68.1 107.8 125.0 70.0 78.3 71.8 93.1 223.0 98.8 88.8 97.3 40.3 128.5 87.3 91.1 68.4 136.2 73.0 101.8 54.0 102.4 90.6 121.7 113.5 109.8 119.1 55.7 75.9 65.5 57.3 61.8 117.6 179.3 64.9 121.0 66.8 54.1 40.6 96.9 94.8 76.7 98.4 72.7 116.1 71.3 121.1 177.3 82.7 84.3 98.7 122.2 53.4 6.4 11.5 12.8 19.0 15.5 21.1 13.0 13.9 14.4 13.5 12.8 15.8 12.2 3.9 14.6 8.0 17.0 12.6 16.8 108.7 106.3 104.9 124.5 105.8 116.3 105.1 112.8 108.1 102.0 120.9 107.2 16.0 22.4 48.5 67.9 28.0 17.8 24.3 32.0 27.9 26.0 48.1 43.1 3.1 42.9 38.5 47.8 47.9 46.5 21.4 18.4 9.8 30.7 4.3 34.6 32.3 20.8 72.3 16.6 9.3 26.0 21.0 24.1 36.7 39.2 29.1 66.7 26.0 44.7 26.8 37.0 17.5 32.3 28.5 19.2 20.2 7.0 38.2 18.7 12.4 22.5 24.7 39.0 12.3 27.2 23.3 28.0 23.5 28.2 29.9 26.2 30.8 31.3 26.2 46.4 26.3 20.0 21.0 43.0 34.9 15.5 11.4 56.5 25.9 44.7 36.4 19.9 WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 126.9" "Cell type enhanced" "Detected in many" "dendritic cells: 172.7;monocytes: 187.2;NK-cells: 245.1;Oligodendrocytes: 217.2;Plasma cells: 162.8;T-cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 209.1;Karpas-707: 296.8;U-266/70: 233.0" "Low region specificity" "Detected in all" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 520000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB009737: AB_2288577, HPA003739: AB_1858783, HPA070706: AB_2686300" "unprognostic (4.76e-2)" "unprognostic (4.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.88e-2)" "unprognostic (1.87e-1)" "unprognostic (2.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (3.65e-2)" "unprognostic (5.43e-2)" "unprognostic (1.58e-1)" "unprognostic (2.50e-2)" 31.0 14.7 14.2 93.0 37.2 56.8 21.0 36.1 20.5 30.6 11.1 26.0 18.2 22.4 11.5 14.2 14.4 34.8 16.0 14.9 28.8 13.0 16.4 31.8 126.9 46.2 38.6 12.3 7.3 12.9 4.8 33.5 42.3 14.9 20.8 3.4 17.7 23.0 5.9 9.9 32.5 29.1 27.9 89.7 21.8 4.7 35.1 66.4 15.4 11.5 110.5 31.5 17.0 53.8 0.7 7.0 16.3 0.2 40.4 70.9 16.9 31.1 26.4 12.1 18.7 1.9 1.4 209.1 9.2 47.0 15.6 0.5 2.8 0.0 15.1 144.8 4.1 106.5 26.9 0.0 15.1 94.9 167.2 29.6 5.1 27.7 2.6 16.0 25.0 18.7 3.3 296.8 34.4 0.1 106.6 87.1 19.1 0.0 1.4 90.0 6.6 37.9 11.3 0.7 2.6 33.8 0.3 8.8 18.7 30.4 0.4 46.8 21.2 41.0 11.5 30.1 29.9 233.0 165.2 113.7 60.4 64.7 111.7 41.5 35.4 87.2 71.6 37.3 59.4 35.1 47.6 71.1 26.1 28.6 38.0 51.4 166.1 57.4 43.7 11.2 57.7 54.7 14.2 37.2 36.1 20.5 14.9 28.8 46.2 38.6 42.3 27.9 35.1 53.8 32.1 19.2 21.7 27.7 134.5 12.5 6.3 0.9 2.8 2.1 3.3 4.3 10.5 1.5 4.6 3.7 25.0 2.0 172.7 0.3 5.9 1.7 40.2 3.3 21.9 30.8 4.9 30.1 5.3 11.6 82.5 40.5 9.7 2.1 67.2 2.1 36.8 3.7 86.2 0.0 7.2 1.6 0.0 142.2 128.0 96.9 25.1 139.8 26.6 98.4 187.2 1.2 245.1 120.6 217.2 16.8 0.8 18.0 162.8 5.0 0.2 35.9 0.1 3.4 13.1 15.7 21.4 4.4 4.1 1.2 11.1 4.1 208.1 8.8 2.1 3.1 WWP1 "AIP5, DKFZP434D2111" ENSG00000123124 "WW domain containing E3 ubiquitin protein ligase 1" Q9H0M0 8 86342547-86478420 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 171.4" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023180 Approved Approved "Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Golgi apparatus, Plasma membrane" "HPA023180: AB_10602587" "unprognostic (3.89e-1)" "unprognostic (6.63e-2)" "unprognostic (3.81e-2)" "unprognostic (7.91e-2)" "unprognostic (3.70e-1)" "unprognostic (1.02e-1)" "unprognostic (1.93e-1)" "unprognostic (4.24e-2)" "unprognostic (1.83e-1)" "unprognostic (9.43e-3)" "unprognostic (3.09e-3)" "unprognostic (1.48e-1)" "prognostic favorable (5.45e-5)" "unprognostic (2.35e-1)" "unprognostic (4.63e-1)" "unprognostic (3.19e-3)" "unprognostic (1.01e-1)" 33.6 22.1 16.3 25.8 21.5 18.2 40.6 19.6 16.3 23.6 24.3 26.9 26.3 23.0 24.6 33.1 18.5 45.3 50.8 14.3 20.7 40.9 111.7 27.2 39.0 18.3 19.0 24.7 28.0 116.3 9.8 36.9 19.7 33.4 33.1 43.2 25.9 25.6 171.4 40.8 28.1 24.6 18.1 45.7 34.3 29.5 19.5 22.7 32.6 122.2 30.6 33.7 15.8 23.1 59.8 27.1 18.3 13.1 23.0 22.4 16.3 21.0 22.5 16.5 19.5 18.9 35.3 24.9 14.0 36.5 22.9 49.3 26.4 34.1 28.5 31.6 21.0 28.7 24.4 44.7 16.8 11.7 14.0 20.5 42.5 18.2 33.3 25.3 74.1 29.0 14.3 28.7 28.4 29.6 27.7 8.1 11.2 82.6 30.0 18.0 21.4 22.5 37.3 44.5 5.5 12.9 21.2 104.7 23.0 39.8 31.3 10.8 84.4 23.9 28.7 26.3 10.7 33.9 22.0 25.7 29.9 1.6 19.0 6.2 2.1 3.9 5.2 1.9 4.6 2.7 6.4 5.3 1.5 2.4 7.5 4.7 1.3 2.4 2.2 1.9 6.5 2.0 16.3 21.5 19.6 16.3 14.3 20.7 18.3 19.0 19.7 18.1 19.5 23.1 51.2 25.6 22.6 29.0 13.0 35.8 26.9 15.4 26.7 28.8 41.7 23.5 82.7 44.3 19.2 29.5 58.4 28.3 19.5 23.7 43.0 20.5 42.1 22.6 20.1 32.3 23.6 3.0 55.3 37.6 3.3 27.6 35.2 35.5 3.8 18.0 62.4 88.8 55.9 40.4 134.6 25.3 14.2 95.2 28.1 12.7 32.3 43.0 30.2 61.8 18.6 23.3 18.6 60.3 103.8 45.1 16.0 36.5 18.5 45.1 15.8 45.7 17.2 52.6 6.6 18.8 16.6 12.4 21.2 28.8 39.5 23.0 32.0 25.1 19.7 38.3 XAGE2 "CT12.2, GAGED3, XAGE-2, XAGE2B" ENSG00000155622 "X antigen family member 2" Q96GT9 X 52369021-52375680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 199.5" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 1027.3;Extravillous trophoblasts: 1890.1;Syncytiotrophoblasts: 1367.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 96.3;SK-BR-3: 22.7;SuSa: 27.9;T-47d: 20.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "unprognostic (1.49e-1)" "unprognostic (4.47e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 5.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 199.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 96.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 4.3 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.7 1.2 27.9 20.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 38.5 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1027.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1890.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 1367.6 0.0 0.0 0.0 0.0 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XIAP "API3, BIRC4, hILP, ILP-1" ENSG00000101966 "X-linked inhibitor of apoptosis" P98170 X 123859724-123913976 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Ubl conjugation pathway, Wnt signaling pathway" "Protease inhibitor, Thiol protease inhibitor, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009203, HPA042428" Approved Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Cytosol" "Plasma membrane" "CAB009203: AB_2257167, HPA042428: AB_2677993" "prognostic unfavorable (9.21e-4)" "unprognostic (8.43e-2)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.40e-1)" "unprognostic (9.41e-2)" "unprognostic (1.95e-2)" "unprognostic (8.51e-2)" "unprognostic (9.17e-2)" "unprognostic (3.90e-2)" "unprognostic (7.50e-2)" "unprognostic (4.41e-2)" "unprognostic (3.15e-3)" "unprognostic (8.21e-3)" "unprognostic (2.26e-1)" "unprognostic (4.99e-2)" "unprognostic (4.65e-2)" 9.2 7.7 6.5 9.2 7.5 8.3 9.7 6.8 7.0 9.6 12.9 12.4 10.1 8.4 10.0 11.5 7.4 8.6 7.8 5.8 8.2 11.8 12.1 8.5 10.4 7.6 8.1 7.5 8.3 18.4 6.3 8.6 7.3 8.5 10.1 21.4 8.6 7.4 10.3 8.8 10.1 7.4 8.5 10.4 10.2 4.2 8.1 8.9 14.9 11.9 8.6 9.6 6.1 10.3 15.8 13.2 10.2 8.8 11.8 15.0 13.3 16.9 12.4 8.9 7.7 5.9 17.9 14.7 24.3 14.4 17.1 5.6 15.3 10.5 16.3 15.5 8.3 9.9 11.1 9.2 14.9 18.1 19.7 10.4 16.0 14.9 19.0 10.2 12.7 10.8 15.9 16.4 17.6 16.5 10.2 8.8 8.4 15.6 10.3 10.8 11.9 15.6 13.4 22.6 6.8 10.0 22.9 13.0 13.5 9.0 8.0 8.7 15.7 0.5 6.0 27.0 18.9 13.8 14.9 15.8 18.3 12.7 11.5 9.3 1.8 2.6 3.3 1.5 3.0 3.1 2.4 3.6 1.0 4.0 2.7 1.9 5.6 2.4 2.9 2.9 1.8 1.5 6.5 7.5 6.8 7.0 5.8 8.2 7.6 8.1 7.3 8.5 8.1 10.3 50.0 80.1 91.6 26.4 42.1 26.6 36.3 35.0 28.5 72.1 29.7 19.9 44.5 44.3 55.2 53.3 95.9 17.9 41.7 122.9 27.4 36.0 2.7 38.4 44.9 55.0 47.4 23.5 30.0 54.0 30.0 38.4 39.8 50.4 60.7 30.9 64.2 85.8 29.0 75.7 34.9 62.2 26.4 43.6 33.0 4.1 42.6 44.2 8.8 29.0 45.8 45.8 55.6 32.6 41.9 65.4 53.5 51.6 39.5 53.0 59.2 59.8 50.6 133.7 65.7 43.6 34.9 15.2 21.0 30.8 35.5 38.0 40.8 30.0 48.0 68.1 XIRP1 "CMYA1, DKFZp451D042, Xin" ENSG00000168334 "Xin actin binding repeat containing 1" Q702N8 3 39183210-39192596 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 682.0;skeletal muscle: 383.4" "Cell type enriched" "Detected in some" 15 "Cardiomyocytes: 850.5" "Cancer enhanced" "Detected in some" "head and neck cancer: 2.0" "Region enhanced" "Detected in some" "cerebellum: 2.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HSkMC: 4.4;LHCN-M2: 1.1;RH-30: 3.0" "Not detected" "Not detected" "HPA016750, HPA018458, CAB026391" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" Nucleoplasm "CAB026391: , HPA016750: AB_1858884, HPA018458: AB_1858885" "unprognostic (2.19e-1)" "unprognostic (6.40e-2)" "unprognostic (1.13e-1)" "unprognostic (9.75e-2)" "unprognostic (2.76e-1)" "unprognostic (2.43e-2)" "unprognostic (4.94e-2)" "unprognostic (2.66e-3)" "unprognostic (1.66e-3)" "unprognostic (1.46e-1)" "unprognostic (5.30e-2)" "unprognostic (6.26e-2)" "unprognostic (1.02e-5)" "unprognostic (2.08e-2)" "unprognostic (2.78e-2)" "unprognostic (6.86e-4)" "unprognostic (4.12e-2)" 1.1 0.3 0.0 1.2 0.0 0.0 0.2 2.0 0.3 0.0 0.1 0.7 0.0 0.2 0.0 5.6 0.0 1.0 682.0 1.1 0.1 0.1 0.1 1.7 0.0 0.6 0.2 0.1 1.2 0.0 0.5 0.7 0.2 3.4 0.0 0.0 5.1 0.0 383.4 0.5 0.5 0.4 0.2 0.6 0.3 0.0 0.1 0.5 0.2 96.4 0.0 3.5 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.3 1.1 0.1 0.6 0.2 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 850.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 4.2 0.0 0.0 0.0 0.0 0.0 11.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 53.4 3.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167" "unprognostic (7.46e-2)" "unprognostic (2.52e-2)" "unprognostic (4.50e-2)" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (2.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.65e-2)" "unprognostic (1.50e-1)" "unprognostic (7.13e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "prognostic favorable (4.14e-7)" "unprognostic (1.59e-1)" "unprognostic (7.88e-2)" "unprognostic (7.62e-2)" "prognostic favorable (2.46e-4)" 22.9 17.2 14.3 16.4 17.3 10.2 22.9 15.6 14.6 27.2 15.2 20.1 19.0 24.9 17.6 16.1 25.3 16.6 13.1 12.9 17.3 24.8 24.2 20.7 24.5 16.8 17.4 34.6 21.6 24.0 25.8 15.6 17.4 22.9 15.6 15.2 18.5 23.6 21.3 31.9 24.0 17.5 15.2 24.2 17.4 12.4 16.0 21.2 26.7 9.8 21.7 22.9 20.3 18.3 14.3 33.8 36.7 22.6 51.0 35.8 124.8 33.6 88.7 29.9 22.3 11.8 14.7 46.6 14.5 37.5 14.7 15.6 23.6 49.3 23.6 21.5 24.7 24.9 35.7 21.7 45.0 16.8 42.2 50.1 56.4 39.7 77.4 34.2 34.5 19.0 31.2 22.5 32.5 27.2 17.9 16.3 23.5 20.4 21.2 19.3 17.9 33.7 36.2 36.9 8.8 29.9 36.1 27.2 23.5 54.6 29.9 13.8 57.1 11.2 32.1 18.4 15.4 54.5 46.4 25.4 26.5 19.4 41.6 41.4 20.2 26.8 23.2 16.6 22.7 27.1 26.7 23.5 17.9 25.0 28.3 20.8 73.1 24.3 23.3 17.4 24.7 16.9 14.3 17.3 15.6 14.6 12.9 17.3 16.8 17.4 17.4 15.2 16.0 18.3 26.0 60.9 63.2 16.6 39.9 13.8 20.4 25.5 59.2 35.6 19.0 25.9 11.8 31.5 47.7 16.5 39.6 42.5 38.9 13.4 35.2 19.3 2.3 32.2 44.8 29.9 16.3 20.8 18.0 19.2 20.3 29.2 15.3 25.5 47.4 25.0 22.9 40.5 18.2 26.9 22.0 13.9 20.3 23.9 14.9 2.7 30.7 19.6 8.8 15.0 40.1 24.9 54.6 17.1 27.5 19.5 15.0 28.2 29.1 18.9 32.7 66.1 55.0 51.0 26.3 43.3 27.7 28.7 54.9 21.4 11.1 32.0 42.3 26.3 18.1 10.5 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XPO6 "FLJ22519, KIAA0370, RANBP20" ENSG00000169180 "Exportin 6" Q96QU8 16 28097976-28211965 "Metabolic proteins, Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 90.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 202.1" "Lineage enriched" "Detected in all" 9 "granulocytes: 202.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038246 Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" No No "Cluster 50: Neutrophils - Cellular senescence" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Nucleoli" "Plasma membrane, Cytosol" "HPA038246: AB_10674550" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "unprognostic (1.07e-1)" "unprognostic (3.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.03e-1)" "prognostic unfavorable (3.68e-4)" "unprognostic (2.22e-1)" "unprognostic (1.41e-1)" "unprognostic (1.31e-2)" "unprognostic (4.48e-1)" "unprognostic (1.40e-1)" "unprognostic (1.01e-3)" "unprognostic (2.10e-1)" "unprognostic (5.36e-2)" "unprognostic (8.50e-2)" "prognostic unfavorable (8.80e-4)" 48.0 48.3 70.0 55.9 73.7 92.0 39.9 61.7 87.0 43.7 63.9 47.0 21.8 42.3 18.8 57.0 44.8 24.5 36.2 72.2 72.0 47.2 62.1 70.9 62.9 76.1 69.2 36.6 43.2 26.9 56.6 25.7 73.6 48.6 27.4 35.2 44.9 20.1 29.9 52.9 63.0 26.8 67.8 160.6 42.8 100.3 72.9 51.1 50.5 13.7 44.9 44.9 46.0 77.8 82.9 63.3 54.8 58.8 37.2 58.8 57.9 97.0 98.0 124.8 124.8 89.1 61.7 59.8 78.6 99.8 63.3 53.8 131.6 83.9 151.5 115.3 72.1 67.6 90.0 101.6 87.9 95.4 70.8 46.3 61.2 111.1 108.9 53.5 73.1 63.4 118.0 31.0 86.0 101.1 116.2 116.1 88.1 43.6 55.4 101.0 64.3 101.2 46.8 45.2 103.3 55.0 52.9 88.3 47.8 60.8 62.7 63.3 75.4 104.1 64.4 87.2 84.8 63.0 83.8 89.8 78.7 98.4 89.1 21.1 9.9 32.9 14.2 11.4 15.4 20.7 16.5 15.8 7.3 15.7 18.1 22.6 202.1 10.7 17.6 9.5 14.7 8.4 70.0 73.7 61.7 87.0 72.2 72.0 76.1 69.2 73.6 67.8 72.9 77.8 9.6 9.6 14.2 27.4 20.2 18.6 11.4 12.6 5.2 20.8 15.0 14.6 8.0 5.7 12.6 23.9 31.3 11.5 30.2 28.5 7.9 14.1 39.2 12.7 21.5 11.6 23.5 10.3 51.2 19.2 17.3 13.3 12.2 32.8 2.5 34.6 9.3 16.7 23.4 21.9 55.4 20.6 10.2 27.9 15.8 44.8 10.8 22.6 7.2 43.1 28.6 8.3 23.7 59.3 90.3 23.4 13.5 8.6 16.5 22.4 13.3 7.1 10.3 28.1 6.6 13.5 12.2 31.6 26.5 18.0 21.3 8.3 27.0 9.5 21.2 15.4 XRN1 SEP1 ENSG00000114127 "5'-3' exoribonuclease 1" Q8IZH2 3 142306607-142448062 "Predicted intracellular proteins" "DNA-binding, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "RH-30: 119.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035005, HPA035006" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA035005: AB_10670695, HPA035006: AB_10672750" "unprognostic (3.52e-1)" "unprognostic (2.35e-2)" "unprognostic (2.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.40e-2)" "unprognostic (1.68e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-2)" "unprognostic (6.32e-2)" 9.0 6.8 2.9 12.2 4.5 21.2 10.7 11.4 5.5 8.4 6.4 8.2 11.0 9.8 7.8 7.0 6.2 8.0 5.5 3.2 4.0 6.8 16.2 8.6 13.1 3.8 3.2 10.1 8.1 8.8 6.0 10.5 4.2 8.8 9.4 14.6 7.4 6.1 11.7 9.4 12.4 6.6 4.5 12.8 9.0 9.3 3.9 14.4 8.7 9.7 11.3 7.7 8.2 6.8 22.1 3.9 9.6 8.6 11.1 17.0 5.9 9.9 12.9 12.3 15.2 3.6 6.1 8.9 10.3 13.3 10.0 8.6 8.6 5.2 19.2 21.4 6.5 12.7 7.3 3.5 9.6 12.8 12.7 14.0 6.1 8.8 11.7 12.1 11.4 9.7 8.0 20.4 11.7 4.5 11.2 7.6 3.0 3.4 4.4 9.0 119.2 11.4 6.5 10.8 5.7 7.3 17.3 10.4 8.2 5.9 11.9 10.8 16.0 9.0 4.7 10.3 8.7 29.1 14.2 13.7 8.4 7.2 7.9 31.0 5.8 17.2 10.0 5.4 7.1 9.8 7.7 9.1 2.9 7.2 10.1 7.0 21.2 5.9 5.0 8.0 6.2 3.1 2.9 4.5 11.4 5.5 3.2 4.0 3.8 3.2 4.2 4.5 3.9 6.8 66.1 54.5 33.3 74.7 55.9 25.6 33.7 22.7 33.6 33.7 27.2 21.0 26.5 18.6 30.2 46.0 50.1 22.9 80.8 46.5 11.7 16.5 49.9 31.9 50.7 40.6 28.2 43.6 101.6 12.5 7.8 41.8 48.4 29.0 21.5 33.7 33.9 48.0 16.3 26.9 114.2 22.5 14.2 28.9 23.0 19.1 24.8 38.8 14.2 81.5 41.4 21.0 50.4 126.7 120.4 18.6 41.9 29.0 111.7 44.0 43.4 13.2 34.2 53.9 6.6 56.0 39.9 61.8 20.5 27.6 28.3 53.5 69.8 37.1 15.0 43.8 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 YAP1 YAP65 ENSG00000137693 "Yes1 associated transcriptional regulator" P46937 11 102110447-102233424 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 145.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009370, HPA038884, HPA038885, CAB069915, HPA070359" Enhanced Supported "Nucleoplasm,Nucleoli,Cell Junctions" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Nucleoli, Cell Junctions" "CAB009370: AB_2273277, CAB069915: AB_922796, HPA038884: , HPA038885: AB_2676255, HPA070359: AB_2732154" "unprognostic (9.56e-2)" "unprognostic (6.75e-2)" "unprognostic (2.08e-1)" "unprognostic (3.03e-1)" "unprognostic (1.35e-1)" "unprognostic (3.16e-1)" "unprognostic (1.95e-1)" "unprognostic (1.28e-1)" "unprognostic (2.66e-3)" "unprognostic (3.73e-1)" "prognostic unfavorable (2.03e-4)" "unprognostic (9.26e-2)" "unprognostic (4.80e-2)" "unprognostic (8.38e-2)" "unprognostic (1.77e-1)" "unprognostic (1.04e-1)" "unprognostic (1.29e-2)" 57.2 27.8 19.1 25.9 19.1 0.3 42.7 18.6 17.1 62.5 44.3 41.5 27.2 78.1 45.9 74.7 65.6 49.3 48.1 15.9 22.1 39.3 33.5 45.7 13.0 31.8 30.2 93.1 22.3 37.0 9.9 83.1 21.8 59.2 30.1 12.9 40.6 83.7 48.3 44.2 27.4 100.5 27.3 14.7 31.6 15.0 27.0 13.8 85.9 58.2 22.7 60.9 52.6 20.2 56.9 52.1 141.5 69.6 151.1 143.1 118.7 130.4 147.8 124.2 101.5 130.2 134.9 0.0 105.4 171.6 92.1 98.0 71.0 186.4 130.6 16.8 25.5 0.1 67.3 89.5 115.3 0.1 2.5 115.2 119.4 136.6 220.2 138.4 39.4 6.7 0.0 0.1 142.1 27.2 2.6 0.4 66.8 135.9 49.3 0.1 79.7 0.3 90.9 99.5 0.4 4.7 153.6 57.2 43.5 129.1 103.2 0.8 43.4 175.4 68.8 89.6 55.7 0.1 0.2 0.8 51.0 0.2 130.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.1 19.1 18.6 17.1 15.9 22.1 31.8 30.2 21.8 27.3 27.0 20.2 28.4 35.3 69.4 145.3 1.5 113.7 47.8 43.5 71.2 0.4 48.1 43.8 39.2 62.9 37.2 92.0 0.0 91.4 0.4 16.2 11.7 27.6 6.7 61.8 53.3 28.9 7.3 0.0 1.5 18.3 20.3 49.0 23.9 85.1 0.0 127.2 26.0 45.2 10.6 0.0 1.6 13.1 14.2 1.6 21.5 4.6 37.9 2.2 44.4 60.0 1.0 27.6 0.0 5.0 0.7 25.2 16.3 40.6 0.1 66.0 27.2 26.1 41.6 1.2 39.5 21.6 62.0 2.5 5.3 59.5 123.2 61.6 2.1 15.9 27.8 65.6 YBX1 "BP-8, CSDA2, CSDB, DBPB, MDR-NF1, NSEP-1, NSEP1, YB-1, YB1" ENSG00000065978 "Y-box binding protein 1" P67809 1 42682418-42703805 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transcription factors" "mRNA processing, mRNA splicing, Transcription, Transcription regulation" "Activator, DNA-binding, Mitogen, Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 2038.9" "Cell type enhanced" "Detected in all" "Early spermatids: 8388.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005875, HPA040304, HPA057159" Supported Supported "Endoplasmic reticulum,Vesicles,Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 1600000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Translation" "Cluster 43: THP-1 - Innate immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Endoplasmic reticulum, Vesicles, Plasma membrane" "CAB005875: AB_2219278, HPA040304: AB_10795364, HPA057159: AB_2683355" "unprognostic (8.59e-2)" "unprognostic (5.16e-2)" "unprognostic (9.27e-3)" "unprognostic (2.68e-3)" "unprognostic (7.76e-2)" "unprognostic (8.03e-3)" "prognostic unfavorable (9.87e-10)" "unprognostic (2.80e-2)" "unprognostic (2.31e-2)" "unprognostic (2.79e-3)" "unprognostic (7.51e-2)" "unprognostic (5.52e-2)" "prognostic unfavorable (3.59e-7)" "unprognostic (3.66e-2)" "unprognostic (2.44e-1)" "unprognostic (1.94e-2)" "unprognostic (3.25e-1)" 532.0 254.5 141.7 422.4 155.4 863.9 401.1 153.3 157.7 331.8 154.4 600.2 364.9 406.2 211.3 365.0 337.0 209.8 789.7 140.6 159.4 318.9 309.9 396.3 407.9 175.1 160.2 311.7 266.7 133.8 122.2 242.2 178.8 307.8 378.1 391.8 270.5 219.5 2038.9 295.0 366.1 338.9 152.7 367.1 405.0 783.5 180.8 353.4 282.0 1133.9 382.2 501.5 332.3 173.5 1552.8 761.5 1020.4 1232.7 991.0 908.1 1200.2 971.5 768.9 1116.6 875.8 1034.6 1253.7 1630.6 1157.5 825.2 495.5 870.2 1162.6 1230.5 1103.9 1087.8 1278.0 1596.4 1491.9 1343.8 786.7 2214.4 1320.7 812.6 1092.3 1094.5 1365.7 630.0 950.3 1271.9 1823.0 720.6 1104.0 837.7 2816.5 2464.6 2902.1 755.0 1006.4 1789.6 1972.5 1938.2 1176.7 933.8 1731.6 1298.5 893.7 1294.0 2038.3 1096.8 443.2 5002.2 862.6 945.4 1748.6 1371.1 2209.3 1213.7 1670.6 2004.8 910.4 1750.3 1049.9 15.3 48.4 69.9 42.9 107.1 52.9 69.4 51.8 43.3 77.4 61.2 44.0 45.9 9.0 35.1 124.2 58.6 69.7 34.1 141.7 155.4 153.3 157.7 140.6 159.4 175.1 160.2 178.8 152.7 180.8 173.5 701.7 173.1 230.9 16.3 818.3 1397.7 1265.9 419.7 747.3 247.8 569.7 564.5 1072.3 441.8 355.5 325.5 150.1 753.9 678.4 620.6 1457.6 1013.6 8388.7 363.5 695.5 755.1 587.8 2244.2 16.2 886.6 1998.9 687.6 461.3 427.0 383.1 489.1 483.3 480.1 1708.7 121.1 27.1 930.2 354.0 1656.0 2342.9 3743.4 751.2 1307.6 905.4 19.7 1171.0 463.8 744.6 23.6 32.7 858.2 975.1 806.1 981.0 1935.1 993.3 1169.8 196.2 602.4 466.8 754.8 1083.7 3245.2 425.5 1113.5 1302.5 481.5 635.6 811.4 1257.7 1697.8 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 YIPF1 "DJ167A19.1, FinGER1" ENSG00000058799 "Yip1 domain family member 1" Q9Y548 1 53851719-53889798 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 80.0;Syncytiotrophoblasts: 129.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014716, HPA073931" Approved Supported "Nucleoplasm,Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 47: Cytotrophoblasts - Unknown function" "Golgi apparatus" "Nucleoplasm, Plasma membrane" "HPA014716: AB_1847686, HPA073931: " "unprognostic (4.94e-2)" "unprognostic (4.50e-1)" "unprognostic (6.37e-2)" "unprognostic (2.06e-2)" "unprognostic (3.93e-2)" "unprognostic (1.35e-1)" "prognostic unfavorable (1.34e-4)" "unprognostic (1.96e-1)" "unprognostic (6.64e-2)" "unprognostic (2.34e-1)" "unprognostic (1.49e-1)" "unprognostic (2.76e-1)" "unprognostic (1.24e-2)" "unprognostic (7.75e-3)" "unprognostic (2.38e-1)" "unprognostic (5.39e-3)" "unprognostic (6.35e-1)" 7.1 9.2 5.3 6.2 5.6 5.7 8.5 5.8 15.2 6.7 6.9 7.9 6.9 4.1 7.6 9.0 6.3 5.5 6.6 5.9 6.3 11.1 13.5 7.7 7.1 6.7 5.8 7.0 6.8 7.0 6.2 9.7 6.8 11.3 9.2 7.2 11.7 4.8 14.6 9.4 6.9 6.0 6.2 8.2 8.7 7.2 6.0 8.8 22.1 10.4 10.7 7.7 7.1 6.4 11.0 6.4 10.1 7.1 11.9 13.1 9.0 7.7 12.0 14.0 18.3 7.1 3.3 3.8 12.9 9.2 21.6 13.2 12.9 17.0 14.4 27.4 10.3 8.9 6.4 11.6 15.9 10.0 8.1 13.3 15.8 11.3 13.5 12.0 15.0 13.2 9.6 10.0 14.0 9.2 10.8 14.2 7.7 12.7 10.4 6.6 9.3 15.4 11.5 5.8 4.5 5.6 7.4 13.8 35.4 31.0 21.4 11.1 7.1 5.7 5.8 10.4 6.8 20.1 24.7 7.0 9.3 8.1 5.0 19.1 18.4 20.2 11.8 16.5 11.0 10.4 10.0 12.1 16.6 13.8 9.5 9.2 38.3 11.0 23.3 11.5 24.3 16.5 5.3 5.6 5.8 15.2 5.9 6.3 6.7 5.8 6.8 6.2 6.0 6.4 11.6 6.4 12.6 9.8 9.0 8.5 17.6 19.2 9.6 6.6 20.0 12.4 9.6 24.3 24.0 9.2 0.0 80.0 8.5 14.6 11.7 28.3 30.5 11.4 10.9 10.9 9.6 12.2 9.8 32.6 28.4 9.9 9.7 14.7 9.5 6.3 11.7 20.8 39.7 10.1 8.2 27.5 30.5 19.4 7.7 54.9 5.9 18.9 10.6 11.2 20.2 16.5 21.6 8.5 11.5 32.5 10.8 9.4 28.1 33.2 12.3 17.7 19.7 6.5 0.0 5.6 17.7 22.2 20.9 12.3 10.9 129.6 10.8 17.7 10.8 29.0 YIPF4 "FinGER4, MGC11061" ENSG00000119820 "Yip1 domain family member 4" Q9BSR8 2 32277904-32316594 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "brain: 129.1;choroid plexus: 65.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017884 Supported Supported "Golgi apparatus,Vesicles,Plasma membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Golgi apparatus" "Vesicles, Plasma membrane" "HPA017884: AB_1853855" "unprognostic (5.61e-3)" "unprognostic (8.50e-2)" "unprognostic (3.88e-2)" "unprognostic (3.17e-3)" "unprognostic (3.05e-1)" "unprognostic (7.64e-2)" "unprognostic (3.45e-2)" "unprognostic (3.61e-2)" "unprognostic (3.69e-1)" "unprognostic (8.70e-2)" "unprognostic (4.15e-1)" "unprognostic (1.54e-1)" "unprognostic (2.29e-3)" "unprognostic (1.90e-1)" "unprognostic (1.59e-1)" "unprognostic (3.88e-2)" "unprognostic (6.11e-2)" 7.0 6.2 69.9 5.5 66.9 2.5 8.4 69.6 129.1 6.1 65.6 6.9 5.8 6.9 7.2 5.0 5.0 4.5 7.4 71.7 68.8 7.7 9.2 5.6 5.9 69.3 67.7 6.6 14.8 6.5 5.2 5.9 71.9 6.6 6.2 13.1 7.4 5.6 8.0 7.0 5.8 6.5 66.8 6.9 6.4 4.2 67.3 7.9 10.1 6.0 5.1 5.3 5.1 75.4 8.9 4.4 8.6 7.7 9.8 12.4 4.5 7.5 7.5 7.7 5.0 5.9 6.6 4.7 5.1 8.2 7.4 6.8 9.2 6.6 10.0 7.6 14.3 7.6 9.8 10.7 11.5 10.2 6.2 8.7 12.4 6.9 11.0 10.6 6.6 5.2 10.7 9.6 8.5 5.8 8.0 10.6 7.0 9.6 7.5 5.5 12.7 8.9 8.4 3.8 9.6 9.2 6.4 6.4 11.7 5.5 3.5 8.6 7.4 10.1 4.8 7.1 7.2 14.2 19.1 5.8 15.9 9.7 5.7 14.9 5.4 5.7 4.4 5.1 3.7 4.6 4.4 4.1 4.6 4.0 4.5 4.0 14.9 6.4 5.1 5.4 4.6 4.7 69.9 66.9 69.6 129.1 71.7 68.8 69.3 67.7 71.9 66.8 67.3 75.4 61.4 93.0 69.8 13.1 68.5 51.4 56.9 59.5 50.7 113.8 63.3 28.2 88.0 60.1 58.3 42.3 106.3 68.4 81.3 68.8 33.2 45.3 34.7 39.5 57.9 59.0 57.1 86.9 18.8 39.3 69.9 66.6 28.1 40.1 40.0 56.3 67.8 80.9 48.3 101.0 20.1 70.2 50.8 81.7 60.7 21.0 86.6 58.0 81.8 21.5 85.1 53.1 114.4 22.1 31.8 41.8 66.8 74.9 62.6 78.5 62.7 60.1 62.2 122.2 78.9 71.9 66.2 160.2 59.6 41.1 65.9 192.8 60.7 65.4 46.8 74.7 YOD1 "DKFZp451J1719, DUBA8, OTUD2" ENSG00000180667 "YOD1 deubiquitinase" Q5VVQ6 1 207043849-207052980 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway, Unfolded protein response" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 58.6" "Cell type enhanced" "Detected in all" "Erythroid cells: 70.9;Glandular and luminal cells: 118.8;Late spermatids: 103.3;Urothelial cells: 86.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HEL: 86.3;K-562: 61.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028400, HPA028439" Uncertain Supported "Nucleoplasm,Plasma membrane,Cytosol" NA NA 110000 "Cluster 10: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 1: K-562 - Erythropoiesis" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane, Cytosol" "HPA028400: AB_10599854, HPA028439: AB_10600994" "unprognostic (3.69e-2)" "unprognostic (8.72e-2)" "unprognostic (1.17e-1)" "unprognostic (2.39e-1)" "unprognostic (2.03e-2)" "unprognostic (3.28e-2)" "unprognostic (9.87e-3)" "unprognostic (9.38e-2)" "unprognostic (2.31e-3)" "unprognostic (8.96e-2)" "unprognostic (1.47e-3)" "unprognostic (1.03e-2)" "unprognostic (6.07e-2)" "unprognostic (6.86e-2)" "unprognostic (2.83e-1)" "unprognostic (1.79e-2)" "unprognostic (3.62e-1)" 3.0 4.5 3.5 4.3 3.8 58.6 5.4 3.7 5.5 5.2 3.9 3.9 4.2 3.7 2.9 24.6 2.6 2.8 4.4 4.0 3.4 4.7 5.4 8.5 4.7 5.5 3.6 2.9 3.2 1.6 2.7 5.7 4.4 3.0 3.9 7.6 6.6 2.7 4.8 15.6 4.8 2.5 3.6 5.7 8.8 3.8 5.0 9.9 5.3 4.1 7.6 4.6 10.9 9.9 11.8 6.1 9.5 5.7 3.3 4.4 18.5 7.6 5.9 5.7 5.7 11.7 11.9 6.1 3.0 4.7 2.7 12.6 0.1 9.3 6.4 4.9 10.3 86.3 27.6 5.6 3.1 11.5 29.2 3.1 7.1 4.6 17.7 6.7 5.0 12.5 61.1 0.0 5.0 0.1 10.1 6.3 9.1 4.9 13.5 5.1 0.4 4.5 5.7 13.0 5.0 11.0 12.5 14.4 16.7 8.4 5.1 8.1 2.4 4.8 12.6 4.0 10.0 9.5 0.6 9.0 5.7 0.0 3.3 1.0 0.3 0.5 0.2 0.3 0.3 0.0 0.3 0.2 0.3 0.1 0.3 0.4 0.7 0.3 0.2 0.1 0.2 0.2 3.5 3.8 3.7 5.5 4.0 3.4 5.5 3.6 4.4 3.6 5.0 9.9 6.8 41.7 12.2 20.5 3.3 31.6 29.4 8.1 21.1 8.0 6.2 3.8 7.0 2.8 10.0 1.8 4.2 2.7 8.2 39.4 1.9 4.1 35.4 50.5 19.0 6.7 8.9 70.9 8.5 10.5 3.2 5.5 36.2 118.8 8.2 6.1 2.9 8.6 2.8 11.8 6.4 5.0 12.2 10.0 12.5 103.3 1.5 8.3 14.2 6.5 5.2 4.9 6.2 6.0 16.4 24.4 67.8 2.2 4.8 38.2 7.8 7.0 21.6 17.9 6.6 3.6 6.0 10.9 4.6 33.9 40.2 1.8 6.9 9.0 7.5 86.5 YTHDC1 "KIAA1966, YT521, YT521-B" ENSG00000083896 "YTH domain containing 1" Q96MU7 4 68310387-68350090 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036462 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane" "HPA036462: AB_10669793" "unprognostic (1.02e-1)" "unprognostic (8.44e-3)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-3)" "unprognostic (8.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.63e-2)" "unprognostic (1.70e-1)" "unprognostic (4.05e-1)" "prognostic favorable (7.29e-5)" 43.0 27.0 22.4 19.5 26.5 116.6 43.8 31.9 25.0 52.6 18.6 40.0 15.6 43.6 22.7 48.0 42.3 15.3 34.1 20.9 26.0 38.2 33.1 40.6 28.4 23.6 23.6 68.6 44.5 20.3 41.2 23.8 24.8 37.9 19.6 38.5 42.1 17.6 47.2 51.3 40.5 17.2 23.2 41.9 36.3 31.3 23.1 30.3 42.1 16.7 26.7 37.3 50.5 32.7 31.8 18.4 37.1 22.2 21.7 18.8 30.4 33.8 21.3 20.6 21.5 22.9 27.9 50.8 27.0 17.2 16.7 23.3 35.1 29.4 33.1 38.2 21.3 38.8 27.3 25.6 22.1 41.5 29.0 17.8 31.3 18.5 44.0 26.6 22.6 24.7 37.5 29.0 30.7 23.9 48.9 37.1 27.6 30.4 18.0 42.4 41.6 22.8 32.6 35.6 31.9 24.8 29.5 31.5 25.9 34.3 24.6 28.8 24.1 23.5 24.9 16.4 22.5 30.1 21.8 53.7 15.9 26.6 22.0 69.3 20.3 40.4 24.1 12.7 19.0 36.1 19.6 19.8 12.2 44.8 26.9 22.9 105.4 20.8 27.0 39.3 20.3 9.7 22.4 26.5 31.9 25.0 20.9 26.0 23.6 23.6 24.8 23.2 23.1 32.7 104.6 112.2 129.5 54.9 104.7 119.9 103.6 76.2 88.8 105.8 112.8 107.2 92.6 85.8 125.1 73.5 70.9 73.6 136.8 58.1 52.8 70.2 98.5 131.9 135.3 92.2 85.8 74.7 43.8 57.2 124.8 81.3 54.0 254.8 94.7 86.2 63.5 85.6 43.2 90.9 49.4 77.9 63.1 61.0 75.9 22.0 74.6 84.5 64.0 56.2 67.0 99.2 96.8 59.3 110.1 81.6 56.0 67.7 103.2 121.6 42.0 44.0 113.2 138.4 52.6 122.0 98.8 139.2 95.9 127.1 134.5 119.0 122.0 59.5 66.9 119.8 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.7;JURKAT: 31.0;MOLT-4: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 10.3 3.3 9.3 1.9 14.2 2.6 8.8 9.4 10.8 6.7 7.5 4.2 3.9 10.2 7.4 2.4 7.0 3.5 4.6 7.8 9.2 10.0 10.7 5.0 1.9 16.0 12.2 7.9 7.6 8.4 3.9 2.4 10.9 5.1 4.3 3.8 6.0 6.6 2.7 2.6 3.3 8.7 9.9 3.6 6.4 1.9 13.5 4.8 11.2 3.8 1.9 3.0 3.7 17.1 5.2 4.2 5.4 29.7 22.1 1.5 0.3 1.7 5.0 2.6 6.9 9.1 2.4 0.0 10.9 3.4 1.1 0.6 2.9 1.8 2.3 1.7 5.8 4.0 9.1 10.4 13.1 5.5 1.5 24.6 6.8 1.3 5.1 4.2 8.3 31.0 0.0 11.0 1.6 5.2 29.4 0.8 3.5 1.4 2.5 12.1 10.3 1.7 12.3 2.0 5.9 12.4 6.1 5.0 8.7 2.1 7.5 3.8 3.3 2.3 4.5 5.1 7.0 8.0 8.2 11.5 3.6 10.4 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 9.3 14.2 9.4 10.8 7.8 9.2 16.0 12.2 10.9 9.9 13.5 17.1 10.5 0.0 2.8 8.1 1.7 1.3 3.8 0.3 4.0 8.4 13.5 13.6 10.7 12.8 2.0 12.9 12.5 1.5 2.0 3.1 17.6 4.1 3.3 16.5 13.5 11.7 16.2 5.0 3.3 6.0 0.3 9.3 11.7 12.5 1.3 20.2 12.1 31.8 9.6 3.3 8.5 5.3 0.0 13.6 4.9 2.2 17.7 9.0 7.2 5.6 5.1 13.8 3.1 16.1 18.3 2.7 3.4 11.3 1.4 5.6 1.9 17.2 0.1 17.0 0.0 21.4 7.7 1.5 3.4 2.2 1.4 0.3 1.2 25.6 7.1 1.8 ZBTB33 "kaiso, WUGSC:H_DJ525N14.1, ZNF-kaiso, ZNF348" ENSG00000177485 "Zinc finger and BTB domain containing 33" Q86T24 X 120250752-120258398 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation, Wnt signaling pathway" "Activator, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000755, CAB001980, HPA005732" Approved Enhanced "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 65: Plasmacytoid DCs - Unknown function" "Nucleoplasm, Plasma membrane, Cytosol" "CAB001980: , HPA000755: AB_1079167, HPA005732: AB_1079166" "unprognostic (9.14e-3)" "unprognostic (1.45e-2)" "unprognostic (1.17e-1)" "unprognostic (1.01e-2)" "unprognostic (2.47e-2)" "unprognostic (6.13e-2)" "unprognostic (1.72e-2)" "unprognostic (1.94e-1)" "unprognostic (1.04e-1)" "unprognostic (1.52e-1)" "unprognostic (1.25e-1)" "unprognostic (4.51e-2)" "unprognostic (5.08e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (6.44e-2)" "unprognostic (2.59e-2)" 6.4 7.0 6.4 8.5 7.0 19.5 15.4 7.1 9.0 6.8 4.7 6.8 7.7 6.2 9.4 9.9 8.2 7.3 4.9 6.4 9.2 6.4 19.0 8.7 13.2 7.3 8.7 9.7 8.4 13.7 4.8 8.8 8.5 7.4 6.5 5.7 10.4 6.0 5.4 18.8 6.4 4.8 8.4 11.5 8.6 5.7 9.3 16.2 10.2 7.7 12.8 8.0 4.8 9.7 13.6 12.9 19.6 18.1 15.9 17.8 23.4 10.3 13.5 11.7 14.5 9.0 11.7 19.5 18.8 10.4 15.7 20.7 31.9 15.7 15.3 22.0 21.6 20.3 20.3 12.7 11.6 21.2 22.7 12.7 19.9 11.2 17.6 17.1 20.9 18.7 13.5 23.2 14.6 15.6 19.2 14.1 24.3 20.9 15.3 21.9 14.9 32.0 12.5 22.2 35.6 15.2 20.9 21.3 25.3 14.9 11.5 29.6 19.6 9.5 6.9 14.3 18.5 12.7 13.1 24.7 12.6 29.4 11.9 11.5 4.2 5.6 2.9 6.4 5.0 2.4 3.8 3.9 6.2 2.2 4.6 3.4 0.9 4.0 4.2 6.7 3.5 3.6 6.4 7.0 7.1 9.0 6.4 9.2 7.3 8.7 8.5 8.4 9.3 9.7 15.7 16.0 7.0 3.9 7.9 12.7 7.8 5.1 12.5 4.5 11.5 13.1 5.2 8.6 11.9 1.8 0.0 7.7 21.7 5.3 1.9 5.5 0.1 12.9 8.7 8.5 8.4 10.3 3.4 6.7 8.7 7.9 7.1 10.3 0.0 16.0 7.9 16.6 7.6 3.3 4.6 7.0 6.1 12.8 10.3 0.4 4.4 8.2 3.6 3.7 14.6 7.0 14.4 5.0 4.6 6.9 5.7 2.6 5.4 9.5 6.8 4.0 15.3 1.6 6.6 6.9 4.1 5.0 10.0 12.7 13.1 9.3 8.7 11.2 6.0 11.9 ZBTB8OS ARCH ENSG00000176261 "Zinc finger and BTB domain containing 8 opposite strand" Q8IWT0 1 32600172-32650903 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046315 Approved Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA046315: AB_2679623" "unprognostic (3.41e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "unprognostic (9.08e-2)" "unprognostic (1.82e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (9.63e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (5.18e-2)" "unprognostic (3.84e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.11e-8)" "unprognostic (1.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-1)" "unprognostic (1.42e-1)" 21.5 25.5 21.1 28.7 21.0 21.5 20.6 23.7 34.4 17.1 20.4 33.8 32.2 16.3 35.6 27.2 18.3 14.7 32.4 20.9 22.5 28.2 34.5 20.3 36.9 20.9 20.8 12.4 27.4 21.5 27.7 14.9 21.1 21.6 33.3 27.6 22.8 15.9 43.6 17.0 29.1 20.2 20.3 27.1 28.5 16.5 21.9 16.9 18.3 35.5 43.8 21.4 18.2 22.2 56.1 31.8 27.9 47.2 47.7 43.3 38.1 62.1 62.3 48.5 49.0 75.5 60.9 62.0 55.9 45.6 53.5 41.1 48.7 48.5 64.4 83.2 44.8 50.5 67.4 127.0 39.2 73.2 44.9 43.4 52.3 42.7 51.2 30.3 53.6 74.6 50.8 81.6 62.9 44.3 56.2 42.4 86.1 86.5 48.7 44.9 59.8 60.7 58.7 65.7 55.9 43.0 50.1 49.9 83.3 74.8 34.2 59.8 38.4 67.2 40.8 55.0 78.9 123.1 130.8 177.0 48.1 89.6 68.1 37.5 57.7 71.5 46.3 71.0 44.8 73.0 50.5 56.0 41.6 54.0 41.9 45.1 66.3 48.0 78.0 53.6 86.1 37.8 21.1 21.0 23.7 34.4 20.9 22.5 20.9 20.8 21.1 20.3 21.9 22.2 39.4 22.4 53.7 32.0 56.3 17.2 31.2 69.5 18.2 46.9 28.5 34.7 69.3 30.0 53.3 38.6 43.8 49.3 54.5 68.8 90.1 60.5 38.1 42.5 38.1 34.4 37.7 46.1 58.3 52.7 61.8 35.9 35.2 45.3 44.2 24.0 33.2 82.5 72.3 16.8 60.5 53.2 71.2 61.9 19.8 30.5 36.7 47.4 51.6 21.5 82.2 35.7 75.2 35.7 46.8 68.4 71.6 46.3 79.9 32.8 115.9 139.4 42.0 56.5 32.9 27.3 51.7 52.9 30.0 28.1 15.6 65.1 50.3 31.2 49.7 37.8 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.3;Excitatory neurons: 8.8;Inhibitory neurons: 13.4;Late spermatids: 5.0;Oligodendrocyte precursor cells: 24.6" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 3.6;NTERA-2: 3.8;RH-30: 6.4;SCLC-21H: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 0.0 0.2 14.9 0.0 15.3 0.0 0.0 25.9 33.8 0.1 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 21.2 12.8 0.0 0.0 0.0 0.0 1.2 22.7 0.0 0.0 0.0 4.7 0.0 1.0 0.0 0.1 7.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.5 51.3 0.0 0.1 0.4 0.0 0.1 0.0 13.9 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 3.8 0.0 0.5 0.0 6.4 0.0 0.0 0.0 7.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 15.3 25.9 33.8 21.2 12.8 1.2 22.7 1.0 0.0 51.3 13.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 24.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZFP41 "FLJ00028, FLJ38705, ZNF753" ENSG00000181638 "ZFP41 zinc finger protein" Q8N8Y5 8 143246821-143262705 "Predicted intracellular proteins" "Differentiation, Spermatogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "HPA047232, HPA056268" Uncertain Approved "Nucleoplasm,Nucleoli,Nucleoli rim,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 9: U-2 OS - Unknown function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Nucleoli, Nucleoli rim" "Nucleoplasm, Plasma membrane" "HPA047232: , HPA056268: AB_2683082" "unprognostic (9.16e-2)" "unprognostic (1.49e-1)" "unprognostic (1.07e-1)" "unprognostic (1.47e-2)" "unprognostic (1.10e-1)" "unprognostic (1.45e-2)" "prognostic unfavorable (3.46e-5)" "unprognostic (4.92e-2)" "unprognostic (7.18e-2)" "unprognostic (3.53e-2)" "unprognostic (4.16e-3)" "unprognostic (2.98e-1)" "unprognostic (1.55e-2)" "unprognostic (6.89e-2)" "unprognostic (1.59e-1)" "unprognostic (3.44e-2)" "unprognostic (3.20e-1)" 2.9 3.5 5.4 2.3 6.6 1.5 2.8 2.8 6.9 3.6 0.0 3.8 3.4 4.2 1.4 2.9 4.1 1.9 3.1 4.9 6.6 3.9 3.4 2.2 2.6 7.8 5.6 5.3 3.5 4.0 5.3 1.1 5.7 3.7 1.5 2.4 4.8 2.6 3.2 4.9 3.6 2.0 2.4 3.2 3.6 6.3 8.2 2.4 4.1 1.8 2.1 3.4 3.0 9.7 6.7 10.5 4.5 6.0 5.1 3.9 5.3 4.0 2.1 7.6 5.2 5.2 5.5 3.7 5.8 5.2 7.7 5.4 4.9 5.2 3.7 5.9 6.0 4.7 5.6 4.1 7.1 1.8 2.8 4.1 7.2 4.9 7.2 5.2 3.6 2.6 10.1 3.5 3.6 12.0 5.0 2.0 6.7 8.2 10.3 2.6 3.7 1.3 3.3 6.0 5.7 7.8 11.2 3.0 5.9 3.8 7.7 3.6 3.8 5.7 10.2 4.5 6.4 5.6 4.6 1.7 5.1 4.5 7.7 0.0 0.1 0.0 0.3 0.2 0.5 0.1 0.2 0.2 0.1 0.2 0.4 0.3 0.0 0.1 0.0 0.9 0.2 0.2 5.4 6.6 2.8 6.9 4.9 6.6 7.8 5.6 5.7 2.4 8.2 9.7 1.6 0.0 2.0 2.9 2.3 1.1 0.7 0.8 0.6 2.5 2.3 1.9 3.2 5.7 1.1 3.7 6.2 0.3 0.8 3.7 1.9 1.9 1.5 1.8 2.3 1.6 3.0 0.8 2.2 0.9 1.1 1.6 2.6 1.2 0.0 2.7 2.5 3.9 1.2 6.7 3.4 2.4 2.0 2.2 0.5 2.6 1.2 1.5 1.8 1.0 0.9 2.5 2.1 1.5 4.4 1.6 4.1 2.2 1.6 0.5 3.4 1.4 3.2 2.0 0.0 1.6 1.9 7.9 3.7 1.8 0.3 0.3 0.9 1.6 3.4 0.4 ZFP90 "KIAA1954, NK10, ZNF756" ENSG00000184939 "ZFP90 zinc finger protein" Q8TF47 16 68530090-68576072 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029017 Uncertain Supported "Vesicles,Plasma membrane,Centrosome" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Vesicles, Plasma membrane, Centrosome" "HPA029017: AB_10669653" "unprognostic (3.27e-1)" "unprognostic (1.71e-2)" "unprognostic (1.56e-1)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (2.47e-1)" "unprognostic (3.68e-3)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (7.33e-2)" "unprognostic (1.35e-3)" "unprognostic (3.43e-1)" "prognostic favorable (1.78e-4)" "unprognostic (1.47e-2)" "unprognostic (2.37e-1)" "unprognostic (1.33e-1)" "unprognostic (9.60e-2)" 7.0 6.3 19.4 7.2 18.6 6.1 11.1 27.0 31.1 11.7 9.9 8.2 2.9 10.8 12.2 5.9 9.5 6.5 8.0 18.2 18.1 8.6 5.4 6.7 9.5 15.2 14.6 12.7 7.4 15.7 13.5 5.8 15.3 9.2 6.2 12.7 6.3 8.8 8.2 9.3 7.3 9.3 11.0 10.5 8.1 9.7 18.2 13.4 8.2 9.0 11.3 7.5 8.0 20.3 10.6 11.4 20.9 19.9 18.1 19.2 9.7 9.7 11.0 13.2 15.2 8.0 7.0 11.5 12.7 12.6 11.1 9.7 12.9 12.5 15.0 10.1 4.7 3.0 2.2 13.4 14.0 0.0 10.3 17.2 20.2 12.1 16.8 23.5 10.7 21.2 5.8 4.1 16.3 18.8 11.6 10.7 7.8 6.3 8.5 21.0 6.5 7.6 9.0 7.2 23.5 17.9 28.1 2.1 10.5 15.4 16.8 14.9 8.4 12.2 7.2 10.4 5.8 8.1 15.9 14.0 4.1 4.0 9.9 7.9 1.5 2.5 5.2 1.6 6.7 4.5 4.9 6.0 2.0 3.3 6.7 5.9 0.3 4.3 1.0 2.3 5.8 2.7 19.4 18.6 27.0 31.1 18.2 18.1 15.2 14.6 15.3 11.0 18.2 20.3 13.1 19.2 8.9 18.6 15.1 3.4 6.4 10.5 14.8 21.1 8.5 9.4 10.5 10.0 9.0 20.2 14.6 3.4 11.8 1.5 7.9 10.2 20.6 9.8 14.4 10.9 16.1 13.2 34.0 6.1 1.7 14.7 5.1 6.5 12.0 30.3 11.0 5.2 6.9 18.5 41.4 4.7 4.1 7.9 5.7 13.2 16.4 8.3 3.6 11.2 6.4 13.0 19.6 31.2 35.5 6.5 3.2 17.7 7.2 5.9 1.3 8.1 24.2 17.3 0.0 12.4 11.0 12.1 19.1 8.6 4.5 1.4 18.7 13.7 4.5 4.0 ZFYVE28 "KIAA1643, lst-2" ENSG00000159733 "Zinc finger FYVE-type containing 28" Q9HCC9 4 2269582-2418651 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 49.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 133.9;Inhibitory neurons: 93.2;NK-cells: 48.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 49.9" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.8;T-cells: 1.9" "Cell line enhanced" "Detected in many" "HMC-1: 12.6;NB-4: 14.2;U-266/70: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038175, HPA057587" Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 24: NB-4 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" Nucleoplasm "HPA038175: AB_10697244, HPA057587: AB_2683477" "unprognostic (1.59e-1)" "unprognostic (4.60e-2)" "unprognostic (7.68e-2)" "unprognostic (3.08e-3)" "unprognostic (9.89e-3)" "unprognostic (3.79e-2)" "unprognostic (3.17e-1)" "unprognostic (1.31e-1)" "unprognostic (1.66e-1)" "unprognostic (4.78e-3)" "unprognostic (2.56e-2)" "unprognostic (3.64e-2)" "prognostic favorable (1.35e-6)" "unprognostic (6.05e-2)" "unprognostic (5.27e-2)" "unprognostic (2.97e-1)" "unprognostic (2.41e-2)" 5.5 8.7 4.6 3.1 7.5 2.1 5.4 49.9 18.0 5.5 0.5 8.0 6.1 4.8 1.6 4.7 5.4 3.4 3.9 7.3 0.3 8.7 6.5 6.2 4.0 9.4 6.9 4.5 5.0 4.3 10.8 1.0 7.4 4.0 2.8 4.0 5.5 2.8 2.9 5.4 8.8 1.5 1.0 6.7 7.2 8.1 5.0 2.6 7.7 1.8 2.0 4.8 4.6 6.2 0.9 1.2 0.2 4.2 2.4 0.8 0.2 2.1 3.5 1.1 0.3 0.1 7.6 0.0 2.2 3.7 2.9 4.4 1.4 0.3 0.7 11.7 1.5 0.3 5.3 0.3 4.8 0.8 12.6 3.3 0.7 1.3 0.1 7.7 3.5 1.1 2.2 9.2 1.0 2.6 0.1 14.2 0.2 2.4 9.3 0.0 0.0 4.7 1.7 0.6 6.6 0.5 2.1 0.1 1.2 0.1 2.8 0.3 0.6 2.0 0.1 6.2 0.2 14.8 11.7 0.2 6.0 2.8 2.0 0.4 0.2 0.0 1.9 0.0 0.8 0.4 1.0 1.3 0.3 1.8 1.3 1.4 0.0 0.2 0.1 0.1 1.9 0.5 4.6 7.5 49.9 18.0 7.3 0.3 9.4 6.9 7.4 1.0 5.0 6.2 12.2 0.0 1.7 41.4 3.7 5.9 3.4 2.1 5.7 12.2 7.6 6.2 3.4 7.2 2.9 11.0 18.8 0.3 25.4 32.3 7.9 3.4 29.1 5.1 4.8 8.0 2.4 1.3 133.9 2.3 0.3 3.6 11.7 6.3 8.9 2.6 5.3 3.7 1.9 8.4 93.2 7.8 2.0 2.2 33.0 8.9 1.5 5.1 7.2 32.8 4.0 1.6 48.4 23.6 36.4 2.6 16.8 2.2 9.8 1.7 18.1 4.2 3.0 17.8 0.0 2.3 3.0 3.1 8.0 6.2 4.8 0.3 31.6 8.2 6.6 5.4 ZGPAT "dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP" ENSG00000197114 "Zinc finger CCCH-type and G-patch domain containing" Q8N5A5 20 63707465-63736142 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 123.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 14.2;Gastric mucus-secreting cells: 13.7;Plasma cells: 26.9;Squamous epithelial cells: 11.1;T-cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056705 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA056705: AB_2683213" "unprognostic (4.50e-2)" "unprognostic (2.74e-1)" "unprognostic (5.30e-2)" "unprognostic (4.42e-2)" "unprognostic (8.58e-2)" "prognostic favorable (6.17e-5)" "unprognostic (1.06e-1)" "unprognostic (6.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.54e-1)" "unprognostic (9.31e-3)" "unprognostic (1.60e-2)" "unprognostic (3.43e-3)" "unprognostic (1.37e-1)" "unprognostic (4.11e-2)" "unprognostic (1.24e-1)" "unprognostic (9.86e-3)" 14.5 17.0 5.3 8.8 5.8 14.8 14.6 5.4 8.9 15.7 7.5 18.0 10.0 16.1 3.4 16.6 14.2 5.5 16.0 5.6 4.7 22.2 123.5 13.0 11.5 7.6 5.4 11.9 14.0 8.4 14.4 6.5 5.9 14.9 3.0 1.4 13.7 6.7 16.7 19.0 14.8 4.9 4.1 20.3 15.3 20.2 5.7 9.5 13.8 4.3 4.1 15.9 15.0 7.4 15.3 19.3 7.4 12.0 6.0 4.2 17.1 15.5 10.1 24.0 10.0 41.6 20.4 15.6 28.9 8.8 23.3 27.4 5.0 18.3 3.0 10.7 13.3 14.8 16.9 43.3 11.7 9.4 25.2 10.7 15.3 9.9 3.9 6.5 13.2 18.5 16.5 13.9 8.0 15.3 22.6 22.1 12.1 22.3 24.0 23.9 5.7 15.7 13.5 14.0 14.0 17.4 22.1 24.7 14.2 3.7 16.9 26.0 15.2 37.2 13.3 14.3 20.1 13.9 24.3 22.2 23.5 9.3 17.0 8.6 21.0 26.5 28.3 21.5 28.1 19.2 24.6 26.3 19.7 16.2 23.9 24.7 21.8 26.4 18.4 28.2 26.2 18.6 5.3 5.8 5.4 8.9 5.6 4.7 7.6 5.4 5.9 4.1 5.7 7.4 0.3 3.2 3.4 4.6 8.0 0.0 0.0 0.1 14.2 1.0 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.1 0.4 1.1 2.1 1.8 6.3 7.4 0.2 0.3 3.3 13.7 0.6 2.5 0.5 0.4 2.3 0.2 0.0 5.8 0.2 0.0 1.3 0.0 0.0 0.0 5.4 1.8 8.4 0.0 0.2 0.0 5.5 4.6 0.4 0.1 0.0 26.9 0.2 0.3 0.5 0.1 1.1 0.0 0.5 1.4 0.3 0.1 11.1 0.3 0.3 8.9 0.5 0.2 0.1 ZMYND10 "BLU, CILD22, DNAAF7" ENSG00000004838 "Zinc finger MYND-type containing 10" O75800 3 50341110-50345732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 120.2;testis: 258.5" "Group enriched" "Detected in many" 11 "Early spermatids: 309.4;Endometrial ciliated cells: 221.8;Late spermatids: 415.3;Respiratory ciliated cells: 390.8;Spermatocytes: 529.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 5.6;U-87 MG: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035255 Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "HPA035255: AB_10601928" "unprognostic (2.93e-3)" "unprognostic (2.98e-3)" "unprognostic (1.15e-2)" "unprognostic (3.85e-3)" "unprognostic (4.44e-1)" "unprognostic (7.78e-3)" "unprognostic (4.71e-2)" "unprognostic (6.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (6.73e-2)" "prognostic favorable (6.75e-5)" "unprognostic (8.25e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" 0.3 0.1 5.0 0.2 5.0 0.7 1.1 3.5 2.8 4.3 29.2 0.2 0.2 1.7 1.6 0.2 120.2 0.5 0.2 4.3 6.7 2.1 0.9 11.1 0.2 12.5 15.6 0.6 1.1 3.7 5.9 0.1 9.4 0.7 0.1 3.2 0.3 0.4 0.4 0.5 0.4 0.5 10.4 0.6 0.3 258.5 7.3 0.5 1.9 0.2 0.1 0.2 0.3 9.2 1.6 0.6 0.2 0.5 0.6 0.9 0.3 0.2 0.9 1.6 0.5 0.0 1.0 0.7 0.6 1.0 0.2 0.2 1.5 0.0 0.1 0.4 0.6 1.5 1.2 0.0 0.0 0.5 0.8 0.0 0.1 2.0 0.1 1.5 0.1 1.3 0.5 0.1 0.2 1.0 0.3 2.7 0.0 0.2 0.7 0.7 0.0 0.5 2.0 0.0 1.8 0.5 0.1 0.5 0.0 0.0 5.6 0.6 0.0 0.3 0.4 0.9 0.1 1.0 0.4 0.1 3.9 2.2 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.0 0.1 5.0 5.0 3.5 2.8 4.3 6.7 12.5 15.6 9.4 10.4 7.3 9.2 0.5 3.2 5.1 1.3 0.7 0.5 0.4 24.2 1.2 1.2 2.3 1.7 0.8 0.0 33.1 1.8 4.2 0.1 1.7 0.2 0.0 1.1 309.4 221.8 2.4 1.2 0.0 3.2 0.5 0.0 0.2 1.1 0.0 3.6 0.0 0.3 0.7 0.4 0.6 0.0 0.3 0.7 22.4 0.0 0.4 415.3 9.0 1.3 1.8 1.0 0.9 1.2 2.1 0.5 1.3 0.1 0.0 5.7 0.9 0.6 0.0 1.0 390.8 7.6 0.0 0.9 9.8 529.7 9.1 1.1 0.4 0.1 1.7 0.2 0.3 0.1 ZNF10 KOX1 ENSG00000256223 "Zinc finger protein 10" P21506 12 133130575-133159465 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 45.5;Excitatory neurons: 46.0;Inhibitory neurons: 48.4;Oligodendrocyte precursor cells: 54.3;Oligodendrocytes: 45.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA003204 Uncertain Approved "Nucleoplasm,Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 51: Non-specific - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Vesicles, Plasma membrane" Nucleoplasm "HPA003204: AB_1080663" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (4.32e-2)" "unprognostic (1.35e-1)" "unprognostic (6.48e-2)" "unprognostic (2.67e-3)" "unprognostic (1.87e-1)" "unprognostic (6.39e-3)" "unprognostic (4.02e-3)" "unprognostic (2.13e-1)" "unprognostic (3.35e-3)" "unprognostic (2.50e-2)" "unprognostic (3.94e-2)" "unprognostic (3.41e-1)" "unprognostic (1.52e-1)" "unprognostic (4.36e-2)" "unprognostic (5.13e-3)" 6.7 14.3 4.9 3.7 5.6 8.6 12.3 8.8 7.6 14.4 6.2 10.9 3.7 15.0 23.4 6.0 12.1 10.3 8.3 5.8 8.0 10.9 10.6 7.6 5.9 4.7 6.8 22.4 13.2 17.3 45.3 5.2 5.6 15.1 6.2 13.1 8.0 12.7 4.9 8.8 7.1 8.6 5.4 6.0 10.5 15.3 7.8 7.7 21.2 6.3 5.8 10.7 8.8 7.1 3.8 2.2 10.8 0.0 11.5 4.8 6.5 4.4 3.9 5.3 3.6 3.9 2.4 0.0 6.0 4.4 2.9 1.7 6.8 3.6 3.9 0.0 6.6 8.0 10.5 4.4 3.5 5.0 2.6 5.0 3.3 5.7 6.3 7.9 4.4 6.3 6.0 0.0 6.3 1.2 12.0 10.6 11.1 2.1 4.4 9.9 6.8 5.4 4.2 7.9 10.7 7.0 8.7 1.4 3.7 4.9 6.6 5.0 4.3 3.9 3.6 3.7 3.7 0.2 0.0 12.8 1.2 1.7 3.7 0.9 0.5 1.4 2.9 0.6 3.2 3.1 3.4 4.1 1.4 3.0 6.5 3.3 0.5 6.3 0.4 3.4 0.9 1.8 4.9 5.6 8.8 7.6 5.8 8.0 4.7 6.8 5.6 5.4 7.8 7.1 6.8 0.0 9.0 39.2 39.6 3.8 5.3 3.9 45.5 15.9 9.9 9.4 7.7 4.3 7.1 0.0 31.3 4.5 9.1 1.8 1.9 2.3 24.6 11.9 7.6 5.0 12.6 5.0 46.0 1.4 2.0 15.5 21.4 11.7 10.8 5.0 1.4 4.9 2.5 5.0 48.4 3.9 6.1 3.8 4.6 6.3 2.8 9.0 3.6 21.5 1.5 9.1 2.1 54.3 45.4 1.0 2.1 6.8 16.3 2.6 2.2 2.5 2.7 16.2 0.0 6.3 14.3 20.4 15.4 21.4 3.8 3.8 21.9 6.0 3.3 1.6 ZNF18 "HDSG1, KOX11, Zfp535, ZKSCAN6, ZNF535, ZSCAN38" ENSG00000154957 "Zinc finger protein 18" P17022 17 11977439-11997475 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 23.0;Late spermatids: 27.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 37.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006144 Uncertain Approved "Nucleoplasm,Golgi apparatus,Plasma membrane,Cytosol" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 27: Brain & Skin - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 29: Early spermatids - Spermatogenesis" "Nucleoplasm, Golgi apparatus" "Plasma membrane, Cytosol" "HPA006144: AB_1080683" "unprognostic (2.99e-3)" "prognostic favorable (6.32e-4)" "unprognostic (2.32e-1)" "unprognostic (2.50e-2)" "unprognostic (4.91e-2)" "unprognostic (2.72e-3)" "unprognostic (2.28e-2)" "unprognostic (5.93e-3)" "unprognostic (1.25e-1)" "unprognostic (2.93e-2)" "prognostic favorable (5.12e-6)" "unprognostic (2.28e-1)" "prognostic unfavorable (3.06e-6)" "unprognostic (1.52e-2)" "unprognostic (9.31e-2)" "unprognostic (3.34e-2)" "unprognostic (3.53e-3)" 7.2 5.7 7.9 5.8 8.6 13.7 6.1 7.7 11.2 6.7 7.4 6.0 5.0 5.3 6.3 7.5 5.7 5.5 5.9 7.9 8.3 5.8 12.4 5.1 8.8 8.4 8.0 5.7 6.0 4.3 7.7 4.0 8.8 8.4 6.7 4.9 5.2 5.1 7.3 9.7 6.6 5.8 7.6 10.2 5.3 14.1 8.1 8.5 6.2 4.6 8.0 6.3 6.6 9.8 3.0 6.1 6.4 9.7 11.9 10.5 3.4 4.3 7.5 5.5 5.9 2.9 5.0 10.3 6.3 4.7 4.8 6.1 5.4 6.8 5.9 7.8 4.5 6.1 6.9 4.0 8.4 3.4 7.8 8.7 10.8 4.2 7.6 6.3 8.4 12.0 3.6 4.7 7.6 3.1 11.5 6.9 4.8 10.9 2.8 9.4 6.5 4.6 8.0 3.6 2.5 5.4 7.3 3.6 5.9 37.2 5.1 3.2 6.7 6.5 3.2 2.9 3.3 5.2 4.1 5.1 7.5 7.9 7.8 10.5 5.9 6.9 10.3 5.9 9.6 9.0 9.3 9.7 5.8 7.2 10.0 10.3 19.1 7.7 8.2 8.6 11.1 6.1 7.9 8.6 7.7 11.2 7.9 8.3 8.4 8.0 8.8 7.6 8.1 9.8 2.5 0.0 2.0 10.1 3.8 2.0 1.7 4.2 4.6 2.0 2.0 1.4 1.6 2.8 2.1 1.8 2.1 2.4 3.5 2.5 1.9 3.1 23.0 1.8 2.8 1.9 1.2 5.2 7.4 0.9 2.2 2.7 2.0 1.8 2.5 5.1 2.5 3.7 4.3 1.7 8.4 4.2 6.1 3.8 1.8 27.3 3.4 3.2 1.8 8.4 3.4 2.0 5.2 7.5 9.3 2.1 5.0 3.4 2.3 1.6 3.9 3.1 2.5 1.2 0.0 2.5 2.3 9.6 4.9 5.0 2.3 1.5 4.7 2.8 3.1 1.1 ZNF185 SCELL ENSG00000147394 "Zinc finger protein 185 with LIM domain" O15231 X 152914442-152973480 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "epididymis: 328.7;esophagus: 326.7" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 32.2;Pancreatic endocrine cells: 72.0;Squamous epithelial cells: 69.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 51.8" "Group enriched" "Detected in many" 5 "granulocytes: 51.8;monocytes: 27.4" "Cell line enhanced" "Detected in many" "A-431: 124.4;EFO-21: 139.9;HBEC3-KT: 100.0;PC-3: 87.7;TIME: 236.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000400, HPA016438" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites,Cytosol" NA NA 220000 "Cluster 18: Basophils - Vesicular transport" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "Actin filaments, Focal adhesion sites" "HPA000400: AB_1080685, HPA016438: AB_1859109" "unprognostic (1.34e-1)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (2.43e-2)" "unprognostic (9.75e-3)" "unprognostic (2.69e-1)" "unprognostic (2.49e-2)" "prognostic unfavorable (1.50e-4)" "unprognostic (7.94e-2)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.30e-5)" "unprognostic (5.18e-2)" "unprognostic (8.12e-2)" "unprognostic (1.99e-1)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.60e-1)" 5.2 11.6 4.0 5.6 4.2 8.7 12.2 4.8 3.7 69.5 10.9 4.5 1.8 21.8 328.7 326.7 16.4 6.7 1.8 3.2 3.9 11.0 2.1 12.1 4.5 3.5 3.8 6.1 4.3 3.7 8.4 24.9 3.5 24.5 4.2 3.4 44.8 144.1 2.9 53.7 2.6 10.3 4.2 4.5 7.4 3.4 4.3 3.6 21.3 2.9 41.0 11.6 117.5 3.9 124.4 25.9 2.4 1.6 3.0 4.0 5.5 6.0 0.4 14.8 2.2 0.9 36.7 1.6 139.9 9.0 1.4 17.3 3.7 100.0 60.1 1.5 2.4 7.9 9.8 4.1 7.0 0.5 0.6 2.9 70.2 1.6 57.0 14.6 76.5 1.6 0.5 1.1 0.4 29.1 0.5 0.7 1.9 31.4 87.7 0.5 0.4 0.9 7.7 11.5 1.0 8.2 0.2 22.7 3.6 23.3 23.3 2.7 236.2 0.8 50.5 3.0 4.5 1.2 1.0 1.1 1.6 8.9 1.7 51.8 27.4 11.4 1.0 24.4 0.6 0.7 0.7 1.2 7.4 0.6 1.1 0.7 18.5 0.5 21.1 4.9 1.0 20.7 4.0 4.2 4.8 3.7 3.2 3.9 3.5 3.8 3.5 4.2 4.3 3.9 1.1 12.8 2.6 1.3 0.7 9.2 6.2 5.7 4.6 0.5 5.7 7.6 0.9 1.5 9.4 9.2 2.1 3.8 1.7 1.0 0.0 8.6 0.6 14.1 4.2 1.1 0.0 0.0 1.0 3.0 5.0 2.2 2.6 32.2 1.3 3.9 1.4 0.1 9.4 0.0 1.7 2.5 2.0 11.3 4.0 0.3 1.2 9.5 3.6 0.0 14.4 4.0 0.0 1.0 1.4 72.0 0.3 1.2 0.1 7.6 0.3 1.2 6.9 0.3 0.0 0.5 1.9 4.2 5.8 69.7 21.2 0.7 0.8 0.4 2.4 21.3 ZNF2 "A1-5, Zfp661, ZNF661" ENSG00000275111 "Zinc finger protein 2" Q9BSG1 2 95165432-95184317 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041358 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" Nucleoplasm "HPA041358: AB_10795539" "unprognostic (1.18e-1)" "unprognostic (6.41e-3)" "unprognostic (5.81e-2)" "unprognostic (9.29e-2)" "unprognostic (4.47e-2)" "unprognostic (6.03e-2)" "unprognostic (1.13e-3)" "prognostic favorable (4.69e-5)" "unprognostic (1.47e-2)" "unprognostic (1.78e-1)" "unprognostic (2.37e-2)" "unprognostic (2.63e-2)" "unprognostic (2.66e-3)" "unprognostic (2.57e-2)" "unprognostic (6.78e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" 2.1 2.6 2.3 2.3 2.5 0.7 2.5 2.7 2.9 3.2 2.0 2.4 2.1 2.4 3.2 2.3 2.9 1.5 3.1 2.2 2.2 2.7 1.9 2.4 3.1 2.3 2.3 3.9 2.1 3.8 1.9 2.2 2.4 2.6 1.7 3.0 2.3 3.2 3.4 2.9 1.8 2.6 2.1 2.9 2.5 3.0 2.3 3.2 3.1 3.6 3.2 2.3 1.8 3.0 4.1 3.7 4.5 7.6 6.2 5.1 2.8 4.0 5.7 6.1 7.7 3.9 2.5 2.2 3.0 4.1 4.3 3.0 5.1 3.2 6.1 5.8 4.0 5.8 2.9 4.9 5.1 2.8 3.4 4.4 4.3 5.5 7.8 6.3 5.1 4.6 3.9 1.9 5.9 3.1 4.2 4.1 1.8 3.3 4.9 4.1 7.4 3.3 3.4 2.3 4.0 5.2 4.1 5.7 4.9 3.8 3.6 4.4 4.0 7.0 4.2 5.4 3.6 3.4 3.3 3.0 4.4 3.7 5.2 5.6 3.4 12.9 6.3 4.8 4.4 5.4 4.9 5.5 4.0 5.1 6.3 6.2 2.6 3.5 4.0 3.1 6.2 4.0 2.3 2.5 2.7 2.9 2.2 2.2 2.3 2.3 2.4 2.1 2.3 3.0 2.1 0.0 1.7 3.3 2.0 1.0 0.7 1.1 1.8 3.3 2.3 1.5 2.6 5.7 2.1 1.8 0.0 1.8 2.9 0.8 5.9 1.8 2.7 1.3 2.0 1.9 0.0 1.3 7.7 2.0 1.4 2.1 1.5 1.2 1.3 4.7 2.5 1.6 2.5 1.7 6.2 0.7 0.0 2.5 1.2 0.8 2.1 2.2 0.0 3.7 0.5 4.2 4.1 7.1 5.7 0.9 0.5 3.0 1.4 0.9 1.5 2.8 2.5 2.7 6.6 1.6 2.0 5.5 7.5 0.9 1.1 1.6 1.6 2.8 1.1 0.7 ZNF20 KOX13 ENSG00000132010 "Zinc finger protein 20" P17024 19 12092843-12140355 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 42.1;Late spermatids: 66.3;Respiratory ciliated cells: 29.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 22.9" "Group enriched" "Detected in all" 5 "granulocytes: 22.9;NK-cells: 6.8" "Low cell line specificity" "Detected in many" HPA020887 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Nucleoplasm "HPA020887: AB_2218842" "unprognostic (1.77e-2)" "unprognostic (1.06e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-3)" "unprognostic (4.00e-2)" "unprognostic (1.08e-4)" "unprognostic (1.69e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-3)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (7.01e-2)" "unprognostic (9.23e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.21e-3)" 0.8 1.2 0.9 1.6 0.9 2.7 3.0 2.1 1.3 1.3 2.3 2.0 0.7 1.2 3.1 2.0 4.9 1.2 0.8 0.9 0.7 1.8 0.8 1.6 2.1 0.9 1.1 1.8 2.1 1.8 1.2 0.9 0.9 1.3 1.8 1.9 2.2 1.5 0.3 2.4 1.4 1.0 0.8 1.3 2.1 6.1 0.7 1.5 3.4 1.1 1.3 1.5 1.2 1.3 2.4 0.0 3.1 6.8 1.2 2.4 2.4 1.6 3.3 1.7 2.4 0.8 0.9 1.8 1.9 2.2 1.7 1.4 1.6 0.5 2.0 1.7 0.6 0.4 2.4 0.8 0.7 0.0 2.2 1.9 3.3 0.8 1.0 2.0 1.3 3.7 1.0 0.3 3.9 0.9 3.0 2.2 5.4 1.2 1.7 2.0 1.6 1.0 2.1 5.4 1.2 3.2 1.6 1.4 2.9 3.0 2.3 3.0 0.0 4.1 1.3 4.3 1.1 3.4 2.0 2.2 0.4 0.0 1.6 16.3 2.5 6.5 1.4 1.3 1.2 1.6 1.4 1.6 1.3 2.6 1.3 1.1 22.9 6.8 1.9 1.7 3.2 1.2 0.9 0.9 2.1 1.3 0.9 0.7 0.9 1.1 0.9 0.8 0.7 1.3 0.4 0.0 0.0 0.0 1.0 0.1 0.8 2.3 1.8 0.6 1.8 1.1 0.8 1.5 1.5 1.8 2.1 1.0 0.9 1.9 1.9 2.1 42.1 10.3 0.7 0.7 4.2 1.7 0.0 2.4 1.3 0.5 3.6 1.4 2.5 0.8 0.4 2.3 1.7 0.0 0.0 2.1 0.0 0.8 1.0 66.3 0.6 1.0 0.0 0.0 1.4 0.4 1.0 0.0 0.0 2.7 2.1 0.0 1.5 1.7 2.9 2.9 29.7 1.4 0.0 0.4 1.0 10.8 1.7 1.8 0.6 1.1 1.2 0.3 1.7 1.6 ZNF227 ENSG00000131115 "Zinc finger protein 227" Q86WZ6 19 44207547-44237268 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030573 Uncertain Approved "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA030573: AB_10610702" "unprognostic (3.01e-2)" "unprognostic (1.79e-2)" "unprognostic (7.14e-2)" "unprognostic (2.77e-2)" "unprognostic (4.74e-2)" "unprognostic (1.66e-2)" "unprognostic (8.05e-2)" "unprognostic (7.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.68e-3)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (9.91e-2)" "prognostic favorable (2.64e-4)" 6.3 6.9 9.5 5.9 10.3 5.0 8.3 14.0 10.7 7.8 8.8 6.9 5.4 8.0 7.6 6.6 8.0 5.9 5.7 9.2 10.5 6.9 7.4 6.1 10.3 9.7 10.1 11.0 6.6 10.4 8.0 7.7 9.9 8.5 5.8 8.7 5.6 6.9 6.4 6.5 5.8 6.8 9.6 9.5 8.6 7.4 10.1 17.2 8.3 6.4 11.2 7.1 6.5 13.2 9.6 13.4 15.8 19.7 12.6 10.9 7.4 9.2 13.1 8.7 17.0 6.6 7.3 16.8 13.9 8.6 10.4 5.5 18.2 9.7 11.7 21.9 22.8 29.3 14.7 8.2 9.0 25.8 12.4 9.9 10.6 8.6 16.0 14.5 13.1 19.2 2.9 0.4 9.4 5.1 24.3 6.8 25.3 9.8 7.0 14.4 15.9 14.4 9.0 17.2 26.7 27.3 20.6 9.2 7.2 15.2 7.7 13.7 11.3 9.6 15.8 7.4 11.8 37.6 54.5 36.1 6.3 10.6 13.1 17.3 4.8 9.9 10.8 3.5 11.8 12.0 10.2 10.6 5.9 12.2 13.3 11.2 4.2 11.9 3.5 6.2 13.5 5.7 9.5 10.3 14.0 10.7 9.2 10.5 9.7 10.1 9.9 9.6 10.1 13.2 8.0 0.0 1.5 13.7 8.1 3.1 3.8 4.8 3.4 6.0 5.4 4.6 7.0 1.5 6.4 5.5 2.1 5.6 6.3 3.3 3.9 4.2 22.6 4.0 4.6 8.4 2.4 7.8 10.5 4.0 4.5 4.4 3.6 3.7 1.3 8.7 8.9 3.9 4.4 8.4 10.3 4.7 2.0 5.7 3.7 30.0 5.6 3.9 1.8 9.4 5.2 6.3 11.3 17.1 16.8 6.1 3.3 5.7 4.0 6.0 4.2 3.3 4.1 5.4 6.6 5.9 5.5 4.4 8.7 3.3 3.8 2.2 6.9 8.6 3.3 2.9 ZNF229 ENSG00000278318 "Zinc finger protein 229" Q9UJW7 19 44417519-44448578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 6.9" HPA001494 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA001494: AB_1080692" "unprognostic (2.59e-1)" "unprognostic (7.41e-4)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (3.90e-1)" "unprognostic (2.17e-1)" "unprognostic (3.34e-2)" "unprognostic (7.18e-3)" "unprognostic (1.17e-2)" "unprognostic (4.66e-2)" "unprognostic (4.18e-2)" "unprognostic (5.04e-3)" "prognostic favorable (8.43e-5)" "unprognostic (3.66e-3)" "unprognostic (2.01e-2)" "unprognostic (2.18e-1)" "unprognostic (4.34e-1)" 0.5 1.7 1.3 0.1 1.4 0.1 1.0 1.3 1.6 1.0 1.7 0.9 0.7 1.1 1.1 0.7 1.9 0.5 1.4 1.4 1.4 0.8 0.7 0.6 0.3 1.3 1.3 2.3 0.8 2.7 1.3 1.1 1.3 1.2 0.1 4.5 0.7 0.8 0.8 0.3 0.4 0.8 1.2 0.6 0.6 0.7 1.5 1.1 2.0 1.2 0.3 0.8 0.5 1.6 0.0 3.7 2.7 0.0 2.9 2.4 0.0 4.4 1.4 2.1 2.8 0.0 0.6 0.0 1.7 2.5 3.4 1.3 0.0 2.8 1.4 0.0 1.4 0.4 1.2 0.3 5.0 0.0 0.0 3.4 0.0 1.7 6.9 2.9 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 3.4 0.0 1.0 0.0 0.0 1.3 2.1 5.5 0.7 1.0 1.9 0.3 0.0 2.0 0.0 0.0 1.9 1.3 0.1 0.5 0.1 3.1 2.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 1.3 1.4 1.3 1.6 1.4 1.4 1.3 1.3 1.3 1.2 1.5 1.6 1.4 0.0 0.0 5.9 0.4 0.1 0.7 2.0 1.8 5.8 2.1 2.2 3.7 0.0 1.3 0.0 4.2 0.9 0.0 0.2 3.9 1.7 0.7 1.6 1.7 1.3 0.0 2.1 3.1 1.2 0.6 1.0 2.6 1.0 0.0 3.4 1.4 0.2 0.7 1.7 4.5 0.3 0.0 0.6 0.0 0.5 0.9 0.3 0.0 1.0 0.1 4.7 0.0 7.5 2.2 2.0 0.3 1.9 0.0 1.6 0.3 1.6 4.5 6.9 0.0 1.0 1.5 1.8 2.4 1.4 0.0 0.8 0.2 3.4 0.5 0.9 ZNF236 ENSG00000130856 "Zinc finger protein 236" Q9UL36 18 76822557-76972901 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008600 Uncertain Approved "Nucleoplasm,Cell Junctions,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Cell Junctions" Cytosol "HPA008600: AB_1080696" "unprognostic (1.38e-1)" "unprognostic (7.24e-2)" "unprognostic (3.13e-1)" "unprognostic (1.99e-1)" "unprognostic (1.20e-1)" "unprognostic (9.88e-3)" "unprognostic (5.51e-2)" "unprognostic (1.77e-1)" "unprognostic (2.83e-3)" "unprognostic (2.43e-1)" "unprognostic (2.77e-1)" "unprognostic (1.34e-1)" "unprognostic (2.95e-2)" "unprognostic (9.40e-2)" "unprognostic (1.74e-1)" "unprognostic (1.37e-1)" "unprognostic (1.37e-1)" 2.5 2.2 3.2 2.2 5.3 4.9 2.4 9.2 4.4 3.0 0.0 2.8 1.9 3.2 2.8 2.5 2.9 2.0 2.3 3.4 4.3 2.0 2.1 2.1 2.6 2.3 3.5 4.3 2.8 3.1 3.6 2.2 2.6 2.6 1.5 2.4 2.7 2.3 2.5 4.1 2.5 2.1 1.4 2.3 2.8 6.8 3.5 4.1 2.6 3.1 2.4 2.6 2.9 5.7 2.5 2.4 4.7 3.4 3.7 3.4 1.9 1.8 2.6 2.9 2.4 2.3 2.3 3.6 0.9 2.5 3.2 4.6 3.0 2.8 2.5 3.8 3.1 3.4 3.9 2.8 2.1 5.7 3.7 3.4 3.1 2.8 4.4 3.4 3.0 5.5 3.3 2.9 3.1 2.2 6.9 3.2 2.5 0.6 2.6 4.3 4.9 2.4 2.4 3.8 2.6 2.8 3.6 2.2 2.5 2.2 2.5 3.9 3.2 5.3 2.0 1.3 2.9 2.0 3.0 4.4 3.6 3.0 3.9 0.7 2.0 3.9 3.1 1.9 3.0 5.9 2.3 2.1 1.4 4.4 2.6 2.7 2.1 1.9 1.8 2.8 2.7 0.9 3.2 5.3 9.2 4.4 3.4 4.3 2.3 3.5 2.6 1.4 3.5 5.7 9.3 9.6 7.9 39.5 11.9 7.1 8.5 5.4 10.8 15.3 8.0 7.6 9.5 12.8 6.7 7.3 10.4 8.4 12.9 5.6 1.9 5.4 6.9 10.8 12.6 9.3 6.0 12.8 37.7 3.9 7.2 8.8 9.2 10.5 1.3 15.8 10.0 6.8 6.0 25.2 25.3 5.0 6.1 7.2 7.2 6.0 10.5 8.7 7.2 16.9 8.4 9.7 9.2 41.7 39.7 4.7 3.1 7.2 9.1 6.8 5.9 3.0 10.9 15.9 6.6 14.2 10.4 26.7 26.2 8.8 8.4 6.0 12.4 7.8 5.7 6.3 ZNF276 "CENP-Z, CENPZ, MGC45417, ZADT, ZFP276, ZNF477" ENSG00000158805 "Zinc finger protein 276" Q8N554 16 89720400-89740925 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "dendritic cells: 63.5;NK-cells: 89.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021309, HPA022255" Uncertain Approved "Nucleoplasm,Nucleoli,Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Cytosol" "Nucleoli, Plasma membrane" "HPA021309: AB_1859024, HPA022255: AB_1859025" "unprognostic (1.45e-2)" "unprognostic (7.05e-2)" "unprognostic (1.17e-2)" "unprognostic (8.25e-3)" "unprognostic (1.17e-1)" "unprognostic (2.95e-3)" "unprognostic (1.27e-1)" "unprognostic (3.70e-2)" "unprognostic (1.92e-1)" "unprognostic (7.85e-2)" "unprognostic (1.59e-2)" "unprognostic (1.36e-3)" "prognostic unfavorable (3.37e-4)" "unprognostic (2.65e-2)" "unprognostic (4.14e-1)" "unprognostic (1.26e-1)" "unprognostic (1.62e-3)" 9.9 12.5 13.3 11.0 14.2 21.0 10.4 13.5 15.9 12.5 9.3 13.0 10.7 10.0 3.5 19.1 14.5 5.3 10.0 12.4 11.8 13.5 14.3 12.0 16.9 15.2 13.2 16.0 13.6 4.4 14.6 4.8 14.0 13.4 5.7 3.8 11.7 4.2 10.6 17.6 19.6 4.5 11.0 26.8 12.0 9.3 14.4 8.1 12.8 4.6 10.6 10.8 14.4 19.7 6.6 5.5 4.8 11.8 3.7 5.4 7.9 5.2 3.0 4.6 1.7 7.4 7.4 8.4 4.6 5.2 2.1 12.1 6.0 5.6 3.1 5.4 25.8 7.9 12.0 3.1 6.8 7.7 9.7 7.3 7.2 6.2 4.7 4.5 5.9 7.7 13.9 7.8 1.9 9.9 9.1 19.3 3.2 7.1 10.6 14.4 5.5 6.0 5.5 3.9 11.5 10.0 9.4 8.8 6.0 2.8 11.8 11.0 7.6 6.3 9.1 5.2 4.3 24.4 8.5 4.7 6.2 14.5 7.2 3.8 1.2 1.5 6.6 1.1 3.3 1.2 3.7 5.4 0.7 1.7 3.7 4.9 3.1 3.8 1.0 1.2 2.7 2.0 13.3 14.2 13.5 15.9 12.4 11.8 15.2 13.2 14.0 11.0 14.4 19.7 17.1 9.6 13.3 15.7 20.8 11.5 8.3 11.2 14.8 15.8 13.9 11.7 2.6 12.8 10.7 11.0 20.9 4.6 63.5 16.8 1.9 7.6 1.9 11.5 14.7 13.6 7.2 13.5 17.6 6.6 3.9 9.5 15.8 14.4 12.6 14.3 20.0 11.5 9.0 6.7 14.6 14.5 2.0 9.8 9.8 2.3 11.5 19.7 8.8 18.7 13.5 9.7 89.6 25.1 30.6 9.2 13.2 10.5 25.4 12.9 19.8 3.4 10.1 21.6 13.1 12.3 8.7 17.0 9.7 15.5 16.1 4.0 39.0 24.0 15.7 11.0 ZNF277 "NRIF4, ZNF277P" ENSG00000198839 "Zinc finger protein 277" Q9NRM2 7 112206695-112343934 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027307 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Plasma membrane" "HPA027307: AB_1859164" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (3.95e-2)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (1.43e-1)" "unprognostic (4.18e-2)" "unprognostic (4.60e-2)" "unprognostic (7.61e-2)" "unprognostic (1.88e-2)" "unprognostic (2.85e-1)" "prognostic favorable (9.47e-4)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 7.5 6.8 3.9 5.4 4.9 6.1 8.9 4.2 7.2 6.1 3.8 7.1 5.9 6.7 3.1 7.1 6.0 6.4 8.0 4.5 3.7 9.5 11.6 7.0 6.8 4.7 3.8 7.1 11.3 7.1 4.6 4.6 4.6 5.6 6.9 4.5 7.1 4.4 6.5 8.3 5.6 6.0 3.8 5.8 7.8 5.4 4.7 7.9 9.4 3.4 6.3 8.2 7.0 7.1 7.6 4.5 7.5 9.3 10.2 28.1 5.6 7.4 7.9 3.5 6.3 6.8 6.8 12.6 13.3 6.1 7.2 5.0 5.7 7.3 9.4 10.2 3.6 6.6 6.1 5.8 6.3 12.1 5.2 17.1 10.8 8.6 5.7 11.1 10.7 13.2 7.9 13.3 6.4 8.8 15.2 20.6 5.1 6.5 5.0 7.4 8.2 11.4 9.5 5.6 5.3 13.8 9.7 12.0 11.9 8.1 3.4 10.2 14.9 5.4 3.1 12.0 4.8 11.5 14.6 14.8 3.9 11.5 6.6 9.3 4.6 6.4 5.7 8.1 8.5 8.7 8.0 8.2 3.7 9.6 9.6 8.1 6.6 7.4 7.2 5.9 9.4 3.7 3.9 4.9 4.2 7.2 4.5 3.7 4.7 3.8 4.6 3.8 4.7 7.1 13.0 38.5 24.6 77.1 25.7 20.6 18.2 35.7 26.2 10.0 19.0 17.5 12.8 27.1 24.1 5.5 2.1 12.3 19.6 12.4 27.4 25.9 46.4 13.6 15.6 17.9 18.5 11.1 51.9 31.0 18.3 15.7 12.8 16.3 7.6 21.4 16.4 19.2 21.7 32.0 43.4 22.5 34.6 46.9 34.8 8.6 17.1 29.1 12.4 43.1 50.6 6.6 37.0 47.7 70.5 24.6 22.9 25.2 13.2 17.5 27.0 34.5 12.7 12.0 19.7 17.1 23.7 32.8 10.4 19.1 24.3 13.8 25.8 28.1 22.4 21.5 ZNF337 dJ694B14.1 ENSG00000130684 "Zinc finger protein 337" Q9Y3M9 20 25673195-25696853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Excitatory neurons: 30.4;Inhibitory neurons: 26.8;Oligodendrocyte precursor cells: 26.2;Oligodendrocytes: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA044303, HPA064219" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nuclear speckles" "HPA044303: AB_2678890, HPA064219: AB_2685215" "unprognostic (2.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (5.81e-3)" "unprognostic (4.54e-3)" "unprognostic (6.99e-2)" "unprognostic (2.34e-1)" "unprognostic (1.34e-2)" "unprognostic (3.15e-2)" "unprognostic (9.36e-4)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.93e-2)" "unprognostic (8.82e-3)" 15.8 13.4 21.5 7.4 21.9 10.3 16.1 28.6 25.5 27.4 23.0 26.5 5.9 21.5 16.1 14.8 26.2 6.9 14.4 20.9 20.6 19.2 11.6 16.6 11.2 20.6 20.3 31.2 13.1 10.4 24.4 7.7 20.5 27.4 8.9 25.9 12.7 13.2 12.5 13.1 18.6 11.7 19.2 21.7 14.0 9.3 20.6 15.3 18.8 8.6 9.5 22.4 19.7 25.3 10.0 17.3 14.0 9.9 11.2 14.3 11.9 8.4 7.3 6.3 7.8 3.6 9.1 12.3 7.8 7.8 12.8 16.0 9.3 27.9 8.7 4.4 7.2 7.5 13.9 15.8 9.6 6.9 8.1 13.3 24.1 7.5 22.1 16.7 10.0 15.7 6.8 10.6 12.5 11.4 18.6 13.4 3.7 5.3 12.2 11.8 12.8 6.0 6.6 11.1 11.2 12.0 8.3 13.4 11.1 17.2 7.7 9.4 13.5 14.1 7.2 9.4 11.3 14.9 8.3 4.3 6.7 5.9 11.2 0.0 1.6 3.2 4.6 2.7 5.0 2.3 3.7 4.2 2.7 1.8 5.2 6.1 0.0 3.9 1.5 2.5 2.5 2.6 21.5 21.9 28.6 25.5 20.9 20.6 20.6 20.3 20.5 19.2 20.6 25.3 8.6 6.4 15.4 26.4 4.3 2.0 5.6 3.4 4.6 8.4 4.1 5.2 1.2 2.8 10.8 3.7 2.1 3.8 4.5 1.2 3.9 4.3 1.4 6.7 8.9 5.6 5.4 1.3 30.4 3.1 2.0 5.4 2.0 4.4 5.1 9.8 3.3 3.2 3.3 6.7 26.8 4.2 0.0 3.1 1.1 0.3 7.2 4.3 1.8 25.3 3.1 7.9 11.3 26.2 29.3 2.7 1.0 5.7 1.7 5.4 1.6 1.9 15.5 13.0 0.0 6.3 4.8 8.1 10.2 3.6 2.4 2.3 6.2 5.4 2.6 1.9 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF397 "MGC13250, ZNF47, ZSCAN15" ENSG00000186812 "Zinc finger protein 397" Q8NF99 18 35241030-35267133 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 94.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026087 Uncertain Approved "Nucleoli,Plasma membrane,Microtubules,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 52: Non-specific - Transcription" "Nucleoli, Plasma membrane, Cytosol" Microtubules "HPA026087: AB_1859243" "unprognostic (1.97e-1)" "unprognostic (2.82e-2)" "unprognostic (2.12e-1)" "unprognostic (3.09e-1)" "unprognostic (6.35e-2)" "unprognostic (1.15e-2)" "unprognostic (1.74e-3)" "unprognostic (1.45e-2)" "unprognostic (1.48e-2)" "unprognostic (3.28e-2)" "prognostic favorable (9.44e-4)" "unprognostic (2.46e-2)" "unprognostic (2.17e-3)" "unprognostic (3.83e-2)" "unprognostic (4.44e-2)" "unprognostic (1.06e-1)" "unprognostic (2.09e-3)" 12.9 13.4 17.6 14.4 23.4 5.0 16.1 19.1 20.0 13.5 14.9 12.8 10.6 15.7 12.4 9.8 11.7 10.1 10.5 16.4 20.7 11.3 10.6 10.4 16.2 20.5 20.9 17.8 12.4 14.8 12.0 11.9 20.1 13.9 13.9 25.0 12.4 12.1 11.7 13.6 12.6 11.5 15.4 16.1 13.3 9.9 20.3 13.1 15.7 11.0 15.8 11.9 11.8 34.4 4.2 7.9 18.7 17.1 20.3 17.0 8.9 8.4 8.3 4.1 5.4 3.0 5.7 21.2 7.4 6.7 5.6 11.1 12.2 9.2 5.7 13.5 7.5 0.9 11.7 8.6 6.7 10.3 7.4 7.7 12.1 4.9 14.1 14.6 2.6 16.1 12.7 14.4 10.7 9.1 17.4 7.8 16.1 3.2 3.2 18.2 5.4 15.1 8.4 11.0 20.2 17.4 13.7 7.2 8.2 16.2 12.5 7.6 4.2 13.6 7.6 4.6 3.8 23.2 9.3 11.9 12.0 7.1 13.1 10.1 4.6 8.3 5.7 7.5 4.1 10.6 5.3 4.7 3.3 11.3 7.8 5.4 11.0 4.7 9.4 7.5 3.0 2.2 17.6 23.4 19.1 20.0 16.4 20.7 20.5 20.9 20.1 15.4 20.3 34.4 15.5 35.3 21.0 24.5 35.3 4.1 19.4 8.0 10.2 51.0 11.8 10.4 16.4 15.7 17.3 14.7 35.5 22.6 15.8 14.1 13.7 18.7 66.0 10.8 20.4 17.6 31.0 20.4 17.4 10.9 13.4 18.4 12.8 8.9 11.4 31.7 31.1 12.6 10.8 33.7 19.5 11.5 12.2 20.5 5.4 49.6 18.6 11.8 8.8 23.4 20.3 24.6 15.5 30.2 94.1 10.7 18.3 22.6 6.1 15.8 24.3 11.4 16.4 46.1 32.9 25.3 16.6 29.7 23.4 7.8 4.5 14.6 13.9 22.1 16.1 11.1 ZNF407 "FLJ13839, FLJ20307, KIAA1703" ENSG00000215421 "Zinc finger protein 407" Q9C0G0 18 74597870-75065671 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 96.9;Excitatory neurons: 111.0;Inhibitory neurons: 100.2;Microglial cells: 113.4;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028255, HPA041673" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA028255: AB_10603466, HPA041673: AB_2677610" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (2.48e-1)" "unprognostic (8.62e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-2)" "unprognostic (1.76e-2)" "unprognostic (4.31e-1)" "unprognostic (1.19e-3)" "unprognostic (4.04e-4)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "prognostic favorable (9.79e-5)" "unprognostic (8.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.11e-2)" 2.4 1.9 2.9 3.1 3.5 5.3 2.9 8.0 2.8 2.7 8.6 2.8 2.2 3.7 1.9 2.5 2.7 2.1 3.2 2.3 2.9 2.4 2.2 2.4 3.3 3.6 3.0 4.8 2.2 3.9 1.5 2.7 4.1 2.8 2.2 2.9 2.4 2.8 3.9 2.3 2.4 3.1 2.9 3.4 2.3 4.0 3.2 5.5 3.6 3.6 3.0 2.4 2.0 4.1 3.9 4.0 4.4 4.1 3.2 4.7 3.2 5.1 4.4 3.7 4.0 1.7 2.2 5.6 1.5 7.1 2.5 4.5 4.2 5.5 5.4 9.3 2.6 7.1 5.5 3.2 2.9 10.9 6.0 4.3 2.4 5.9 5.1 3.5 5.6 3.9 4.1 8.0 5.7 3.1 5.3 1.5 2.6 1.4 3.6 5.4 5.8 4.4 2.6 7.2 4.2 4.0 4.7 2.9 3.6 3.2 3.4 4.6 7.9 8.3 3.5 2.3 4.1 2.8 6.2 5.7 3.0 4.6 5.0 1.6 0.7 0.9 1.0 0.9 1.0 0.8 0.8 0.6 0.3 0.8 0.9 1.1 2.2 1.1 0.6 1.3 0.2 0.4 2.9 3.5 8.0 2.8 2.3 2.9 3.6 3.0 4.1 2.9 3.2 4.1 16.5 6.4 6.3 96.9 10.6 3.2 5.0 3.0 2.8 11.2 6.3 6.0 19.4 2.8 4.9 5.5 6.2 4.2 11.4 6.9 0.0 4.3 4.6 8.6 15.3 10.0 4.2 3.4 111.0 2.9 2.7 7.6 17.3 14.4 1.3 10.2 3.3 5.5 3.2 5.0 100.2 5.7 2.0 5.3 2.8 3.3 5.3 7.6 5.4 113.4 6.1 6.2 8.2 122.6 130.5 4.8 6.0 4.5 11.1 4.4 4.3 2.6 6.2 13.2 6.6 10.8 8.1 9.0 12.8 5.6 4.1 5.2 10.1 12.1 6.0 3.9 ZNF469 "KIAA1858, Zfp469" ENSG00000225614 "Zinc finger protein 469" Q96JG9 16 88382959-88440757 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 7.5;Excitatory neurons: 9.4;Granulosa cells: 9.3;Inhibitory neurons: 8.3;Oligodendrocyte precursor cells: 16.6;Sertoli cells: 6.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 4.3;BJ hTERT+: 4.6;HeLa: 4.7;SiHa: 4.9;THP-1: 6.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA077792 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" Nucleoplasm "Cell Junctions" "HPA077792: " "unprognostic (1.80e-1)" "unprognostic (7.79e-3)" "unprognostic (7.71e-2)" "unprognostic (7.01e-2)" "unprognostic (2.97e-1)" "unprognostic (2.30e-1)" "unprognostic (9.17e-3)" "unprognostic (7.08e-3)" "unprognostic (5.04e-2)" "unprognostic (5.02e-2)" "unprognostic (6.92e-2)" "unprognostic (1.01e-1)" "unprognostic (8.71e-7)" "unprognostic (2.24e-2)" "unprognostic (1.83e-2)" "unprognostic (2.20e-2)" "unprognostic (3.34e-2)" 0.9 0.5 3.2 0.9 1.1 0.1 0.5 0.3 2.0 1.4 0.0 0.3 0.2 1.6 0.0 0.1 0.7 0.9 0.4 3.4 0.4 0.1 0.1 0.3 0.6 2.2 1.6 2.2 0.4 0.1 0.1 0.3 1.3 0.8 0.0 0.0 0.4 0.3 0.7 0.3 0.4 0.8 1.0 0.8 0.4 0.2 1.3 0.4 0.1 0.1 0.2 0.9 0.4 1.2 0.0 4.3 0.1 0.0 0.6 0.9 0.0 2.6 4.6 0.6 0.0 0.0 0.1 0.0 0.1 3.6 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 4.7 0.0 2.9 0.1 0.1 1.0 0.0 1.0 0.0 0.7 2.7 0.0 0.0 0.0 0.7 0.4 0.0 0.6 0.5 0.0 3.4 0.3 0.0 0.0 0.0 0.0 0.0 2.1 4.9 0.0 0.0 0.0 0.9 6.4 3.3 3.6 0.9 2.0 0.7 0.0 0.0 0.0 0.0 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.2 1.1 0.3 2.0 3.4 0.4 2.2 1.6 1.3 1.0 1.3 1.2 0.3 0.0 1.8 2.0 0.8 0.3 0.6 1.1 0.0 0.5 2.1 1.1 7.5 0.0 1.6 0.0 0.0 0.0 0.1 0.0 0.0 2.4 0.2 0.6 1.1 2.3 0.0 0.0 9.4 0.0 0.1 3.9 0.0 0.1 0.0 9.3 2.9 0.0 3.1 3.3 8.3 0.0 0.0 1.4 0.6 0.2 0.0 1.9 0.0 1.9 1.6 0.6 2.1 16.6 0.8 0.7 0.0 1.5 0.2 1.1 0.0 0.2 1.1 0.1 6.6 1.3 4.8 0.1 0.7 0.0 0.1 0.1 0.5 1.7 0.0 0.3 ZNF474 "4933409D10Rik, FLJ32921" ENSG00000164185 "Zinc finger protein 474" Q6S9Z5 5 122129546-122153569 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 4.2;choroid plexus: 7.1;fallopian tube: 17.1;testis: 7.6" "Group enriched" "Detected in some" 5 "Early spermatids: 23.0;Endometrial ciliated cells: 23.2;Late spermatids: 12.4;Respiratory ciliated cells: 22.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.0;CAPAN-2: 1.1;GAMG: 1.3;TIME: 1.2" "Low region specificity" "Detected in many" HPA036594 Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Plasma membrane" "HPA036594: " "unprognostic (9.98e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (5.90e-3)" "unprognostic (7.82e-2)" "unprognostic (2.49e-2)" "unprognostic (3.94e-2)" "unprognostic (7.61e-2)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-1)" "unprognostic (1.06e-2)" "unprognostic (1.51e-3)" "unprognostic (1.12e-3)" "unprognostic (9.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.09e-4)" 0.2 0.1 0.6 0.1 0.7 0.0 0.2 0.5 0.3 0.6 7.1 0.3 0.1 0.7 0.0 0.4 17.1 0.5 0.1 0.6 1.2 0.3 0.1 1.7 0.0 2.2 4.2 0.2 0.1 0.0 0.2 0.0 2.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 1.7 0.1 0.1 7.6 1.2 0.3 0.9 0.1 0.1 0.1 0.1 1.9 0.0 0.4 0.1 0.0 0.2 0.1 0.0 1.0 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.7 1.3 0.2 0.0 0.0 0.4 0.1 0.1 0.4 0.2 0.0 0.2 0.3 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.2 0.3 0.2 0.7 0.2 0.1 0.2 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.3 0.6 1.2 2.2 4.2 2.0 1.7 1.2 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.0 23.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 22.0 0.0 0.0 0.1 0.6 2.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ZNF497 FLJ44773 ENSG00000174586 "Zinc finger protein 497" Q6ZNH5 19 58354357-58362848 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 6.4;Respiratory ciliated cells: 5.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HEK 293: 20.2" HPA047872 Uncertain Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 49: Ciliated cells - Cilium organization" Nucleoplasm "Cell Junctions" "HPA047872: AB_2680196" "unprognostic (8.24e-2)" "unprognostic (1.12e-1)" "unprognostic (2.17e-1)" "unprognostic (1.09e-3)" "unprognostic (1.02e-1)" "unprognostic (1.42e-2)" "unprognostic (2.30e-2)" "unprognostic (8.53e-2)" "unprognostic (9.45e-2)" "unprognostic (9.29e-2)" "unprognostic (4.16e-3)" "unprognostic (7.03e-3)" "unprognostic (1.25e-1)" "unprognostic (1.07e-1)" "unprognostic (4.58e-2)" "unprognostic (7.28e-2)" "unprognostic (1.24e-1)" 0.7 1.4 2.3 1.8 3.3 1.6 1.8 6.4 3.2 2.6 3.7 1.0 1.3 2.3 1.9 2.1 5.7 1.2 1.4 2.7 0.9 3.5 3.1 1.8 2.5 1.6 1.7 2.5 2.5 1.4 4.5 0.9 0.9 2.4 0.8 1.8 2.7 1.1 0.7 2.7 1.2 0.4 0.8 2.3 1.6 1.6 1.6 0.5 3.7 0.0 0.4 0.9 1.7 3.9 2.0 6.8 6.0 5.8 0.2 0.1 7.9 3.7 0.0 0.0 0.0 0.5 2.2 4.0 1.9 0.0 3.3 0.9 0.7 0.4 0.0 4.2 20.2 3.6 2.2 1.2 0.3 1.5 9.2 0.5 0.9 0.1 0.7 6.6 0.0 9.8 3.1 0.6 0.1 7.1 5.1 5.1 3.7 1.7 2.1 12.6 4.4 2.1 0.6 1.6 4.6 6.6 2.0 5.9 3.3 3.0 8.1 4.1 0.6 6.6 3.4 0.6 1.2 8.7 11.1 3.5 1.8 4.1 3.6 1.3 1.1 0.3 0.8 0.4 0.9 1.3 1.0 1.0 1.0 1.5 0.9 1.7 0.3 0.8 0.3 1.8 1.2 0.7 2.3 3.3 6.4 3.2 2.7 0.9 1.6 1.7 0.9 0.8 1.6 3.9 0.3 6.4 0.5 3.9 0.9 0.3 0.4 1.0 1.2 1.4 2.1 1.3 0.7 0.0 1.0 0.0 0.0 2.0 0.1 0.5 1.9 1.4 1.7 3.6 0.6 0.6 0.0 1.3 3.1 0.2 0.5 0.5 1.5 1.2 0.0 1.9 0.0 1.9 0.5 0.0 3.0 1.4 0.0 0.0 0.4 0.9 0.0 0.2 0.0 1.9 0.1 1.3 0.0 3.0 3.5 0.3 1.2 0.0 0.7 0.3 0.4 0.7 5.2 1.6 0.0 0.4 0.4 0.3 1.7 0.8 0.3 0.3 0.5 0.3 1.2 0.1 ZNF503 "FLJ45745, MGC2555, Nlz2" ENSG00000165655 "Zinc finger protein 503" Q96F45 10 75397830-75401764 "Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 255.0;Squamous epithelial cells: 189.3" "Cancer enhanced" "Detected in all" "ovarian cancer: 62.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 115.1;PC-3: 149.2;U-87 MG: 44.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA026848 Approved Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" Nucleoplasm "HPA026848: AB_10610704" "unprognostic (1.18e-1)" "unprognostic (8.56e-2)" "unprognostic (8.63e-3)" "unprognostic (7.41e-2)" "unprognostic (2.82e-1)" "unprognostic (3.57e-2)" "unprognostic (9.63e-2)" "unprognostic (7.42e-2)" "unprognostic (3.42e-2)" "unprognostic (3.22e-1)" "unprognostic (6.53e-2)" "prognostic unfavorable (3.50e-4)" "prognostic favorable (1.97e-4)" "unprognostic (1.53e-1)" "unprognostic (8.28e-2)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" 14.5 39.9 6.1 3.1 10.1 2.0 9.2 3.8 5.2 34.5 1.0 17.7 8.1 44.1 10.3 20.1 23.8 2.4 9.0 7.4 5.5 25.6 7.1 14.2 1.5 12.0 9.2 46.3 25.4 4.6 4.8 3.3 7.6 17.5 1.8 1.4 9.5 17.6 3.6 5.3 8.5 7.7 10.0 8.0 16.3 2.4 8.1 1.1 7.8 2.1 1.0 13.8 18.2 6.5 5.2 4.9 1.1 6.3 10.6 7.1 1.6 4.6 2.8 1.9 1.7 7.5 20.4 0.0 13.4 4.6 1.1 9.4 0.7 4.9 1.4 0.0 115.1 0.0 12.4 24.8 8.5 6.1 12.9 19.1 4.8 3.5 2.0 16.6 0.5 0.5 0.1 0.2 2.6 2.7 0.2 18.8 0.1 3.8 149.2 0.0 5.6 0.1 2.8 4.1 4.1 5.2 8.5 0.6 27.1 1.0 1.0 4.2 3.9 14.6 16.3 30.7 13.0 0.0 0.0 0.0 44.9 27.2 11.9 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 10.1 3.8 5.2 7.4 5.5 12.0 9.2 7.6 10.0 8.1 6.5 27.2 38.5 11.6 2.3 1.7 27.1 35.6 15.0 255.0 23.7 7.7 42.3 20.4 10.0 10.1 40.5 20.9 0.5 2.1 0.8 58.7 45.9 0.1 53.2 72.2 41.0 3.6 5.3 12.6 34.7 0.3 60.1 18.3 48.1 6.3 2.7 44.6 10.3 13.5 6.7 3.2 6.7 10.2 27.4 30.5 2.0 59.7 30.7 24.9 13.1 8.2 7.7 0.0 4.0 0.7 33.2 1.5 49.2 3.9 19.7 13.4 32.5 1.7 26.3 39.5 10.2 78.1 0.2 6.0 189.3 13.9 0.3 4.0 24.5 9.7 14.3 ZNF510 KIAA0972 ENSG00000081386 "Zinc finger protein 510" Q9Y2H8 9 96754553-96778129 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 21.5;Inhibitory neurons: 22.7;Oligodendrocytes: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049139 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA049139: AB_2680651" "unprognostic (2.70e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-1)" "unprognostic (6.92e-2)" "unprognostic (2.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-3)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.94e-4)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (2.18e-2)" 3.6 3.8 4.8 3.3 4.7 2.3 4.8 8.3 6.1 5.2 2.4 3.9 2.6 4.7 3.5 2.7 4.0 2.7 3.6 4.9 5.2 3.8 3.8 3.3 4.3 3.6 4.2 5.7 5.1 5.0 4.6 3.1 3.7 4.3 3.3 11.7 3.3 4.3 4.3 3.4 2.9 4.1 4.0 4.2 3.4 3.3 5.2 5.5 4.7 4.8 4.7 3.7 3.2 5.2 4.2 4.3 8.1 7.2 6.7 6.3 4.0 3.7 6.5 6.1 6.4 3.7 2.7 5.7 2.2 3.7 5.8 8.7 3.2 3.3 5.8 6.5 3.7 6.0 7.0 2.5 3.5 3.5 5.2 4.3 5.8 4.5 6.9 6.5 5.3 8.2 6.8 4.5 7.8 3.9 9.3 5.2 6.6 5.9 3.6 5.6 14.4 2.4 4.3 3.2 9.9 7.8 7.0 3.9 3.8 5.4 3.1 6.2 4.1 4.4 4.5 5.6 5.9 8.8 9.8 3.5 2.7 2.0 4.6 0.4 0.2 0.6 0.7 0.3 1.2 0.9 1.2 0.9 0.2 1.0 1.3 0.9 0.1 1.4 0.8 0.3 0.8 0.4 4.8 4.7 8.3 6.1 4.9 5.2 3.6 4.2 3.7 4.0 5.2 5.2 5.5 3.2 3.2 13.4 4.5 1.7 1.6 1.7 0.6 11.0 2.6 2.5 5.1 1.5 2.9 3.7 2.1 2.2 3.2 1.4 1.9 2.2 5.7 3.5 6.3 4.2 1.2 4.0 21.5 2.6 1.4 5.7 2.0 4.0 1.3 5.7 3.6 1.3 2.0 16.8 22.7 2.1 2.0 2.5 0.5 6.9 5.9 2.2 5.4 10.3 2.0 4.5 8.2 18.1 20.5 1.8 2.8 4.1 3.1 2.0 1.0 1.9 3.2 6.5 6.6 4.6 3.3 3.6 5.6 1.8 1.4 0.8 4.6 4.3 1.5 1.1 ZNF536 KIAA0390 ENSG00000198597 "Zinc finger protein 536" O15090 19 30228290-30713538 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 80.7" "Group enriched" "Detected in some" 9 "Inhibitory neurons: 506.0;Oligodendrocytes: 794.4" "Cancer enhanced" "Detected in single" "glioma: 0.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 5.0;HAP1: 11.0;SH-SY5Y: 29.5;U-937: 7.5;WM-115: 12.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077341 Approved "Nucleoplasm,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Cell Junctions" "HPA077341: AB_2732340" "unprognostic (1.98e-1)" "unprognostic (4.11e-1)" "unprognostic (1.92e-2)" "unprognostic (1.70e-2)" "unprognostic (2.09e-1)" "unprognostic (1.03e-1)" "unprognostic (4.70e-2)" "unprognostic (4.68e-1)" "unprognostic (5.50e-2)" "unprognostic (1.74e-2)" "unprognostic (1.25e-2)" "unprognostic (4.46e-4)" "unprognostic (1.58e-1)" "unprognostic (2.01e-2)" "unprognostic (1.55e-2)" "unprognostic (3.45e-1)" 0.4 2.6 20.7 0.7 43.1 0.0 0.2 28.1 33.2 1.6 17.7 3.6 1.0 0.5 0.3 3.1 0.3 0.3 2.2 18.1 20.2 0.1 0.0 0.2 0.0 36.7 31.2 0.1 0.2 0.3 4.2 0.0 33.9 2.1 1.6 13.7 0.4 0.8 0.4 0.3 1.9 0.3 19.9 0.5 1.1 2.2 36.1 0.0 3.2 0.8 0.0 2.1 1.1 80.7 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 11.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 29.5 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 7.5 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.7 43.1 28.1 33.2 18.1 20.2 36.7 31.2 33.9 19.9 36.1 80.7 0.0 0.0 0.0 11.1 0.0 0.4 0.2 0.0 0.0 33.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.4 0.8 0.0 0.0 2.4 0.0 0.0 4.3 0.0 0.0 0.0 2.3 0.0 0.0 0.7 70.7 506.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 13.1 0.0 48.6 0.0 46.8 794.4 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 9.7 0.0 9.1 1.6 0.3 0.6 0.1 0.3 0.0 0.1 0.0 0.0 0.3 ZNF571 HSPC059 ENSG00000180479 "Zinc finger protein 571" Q7Z3V5 19 37554782-37594792 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "thyroid gland: 77.4" "Cell type enhanced" "Detected in many" "Early spermatids: 20.9;Oligodendrocytes: 23.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" HPA054762 Approved "Nucleoplasm,Nucleoli,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Nucleoplasm, Nucleoli" "Plasma membrane" "HPA054762: " "unprognostic (1.16e-1)" "unprognostic (3.01e-2)" "unprognostic (3.92e-2)" "unprognostic (1.19e-1)" "unprognostic (5.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.19e-1)" "unprognostic (9.03e-4)" "unprognostic (5.77e-2)" "unprognostic (9.82e-2)" "unprognostic (1.22e-3)" "unprognostic (3.90e-2)" "unprognostic (2.14e-2)" "unprognostic (8.93e-2)" "unprognostic (2.62e-1)" "unprognostic (4.89e-2)" "unprognostic (2.71e-4)" 4.1 7.5 8.9 3.6 8.4 8.5 14.5 9.4 11.1 6.4 8.1 3.4 2.2 6.1 9.9 4.1 6.7 5.0 4.2 7.2 9.0 7.4 3.5 3.9 5.5 7.2 8.1 8.3 3.2 12.0 8.9 5.5 7.1 8.0 3.5 28.9 3.3 4.6 4.1 8.5 2.9 4.8 4.5 5.5 3.9 10.6 7.0 6.2 77.4 3.9 6.0 4.5 4.0 9.9 2.5 1.4 8.6 12.5 6.3 6.4 2.8 3.8 6.0 8.9 11.0 2.7 2.4 13.6 11.6 3.9 6.3 3.3 2.8 4.1 14.8 3.0 10.9 7.3 4.4 1.6 7.2 2.7 7.9 3.5 7.2 8.6 7.8 6.3 1.8 12.1 3.5 1.1 7.3 2.4 13.8 3.0 21.7 4.0 4.8 6.8 4.1 7.2 12.4 16.3 18.5 12.9 8.9 2.9 4.5 17.1 13.3 1.9 1.1 4.1 5.2 4.5 9.8 10.5 23.4 18.5 0.6 1.2 9.1 1.6 0.7 4.4 5.2 1.2 4.8 7.6 5.0 5.3 2.3 7.7 6.0 6.6 1.2 3.2 1.1 3.5 3.8 2.7 8.9 8.4 9.4 11.1 7.2 9.0 7.2 8.1 7.1 4.5 7.0 9.9 5.5 0.0 2.0 5.2 6.6 1.8 1.2 1.9 5.2 9.5 3.5 3.2 1.6 1.5 4.6 5.5 10.4 2.4 11.9 0.8 3.9 2.3 20.9 3.1 3.1 6.0 1.2 4.8 8.6 1.6 1.8 3.1 2.0 2.4 15.2 5.1 4.6 0.8 1.7 13.5 9.7 1.9 6.1 1.3 2.1 4.3 4.4 1.7 5.4 5.6 0.6 4.9 5.2 17.1 23.9 1.0 1.0 2.6 3.5 1.9 1.1 2.8 4.0 16.0 13.1 4.9 4.2 10.3 6.2 2.9 2.6 1.2 8.7 4.1 1.7 0.5 ZNF598 "FLJ00086, HEL2" ENSG00000167962 "Zinc finger protein 598, E3 ubiquitin ligase" 16 1997654-2009821 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041760, HPA041896" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA041760: AB_10792490, HPA041896: AB_10796464" "unprognostic (9.43e-2)" "unprognostic (1.34e-2)" "unprognostic (8.17e-2)" "unprognostic (6.76e-3)" "unprognostic (3.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.22e-2)" "unprognostic (7.07e-3)" "unprognostic (1.22e-1)" "unprognostic (4.45e-2)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (4.69e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.81e-2)" "unprognostic (7.81e-2)" 15.0 10.1 2.3 6.8 2.2 11.8 13.9 2.3 5.3 15.4 0.9 14.7 7.0 15.4 0.0 19.4 13.1 2.6 11.6 2.5 2.1 13.1 21.0 15.3 5.5 2.9 2.4 12.4 32.3 2.2 16.3 5.0 2.3 16.2 1.4 0.4 18.7 4.4 26.7 30.0 14.8 2.1 1.7 18.6 14.9 17.6 2.6 5.1 10.8 3.8 2.9 15.8 15.3 2.0 22.8 30.1 7.0 17.5 4.9 6.6 22.0 17.3 7.4 10.5 8.3 31.9 12.4 23.4 20.0 6.7 7.7 27.0 9.3 17.3 1.7 31.2 69.9 18.6 33.5 18.3 22.3 29.3 20.0 7.9 23.2 16.6 18.9 1.1 11.6 27.2 41.3 31.5 4.0 40.5 25.2 45.0 21.6 8.9 35.4 62.4 14.2 52.9 4.0 8.7 33.5 28.9 17.4 20.4 28.3 1.3 14.5 46.6 20.6 23.0 27.6 21.0 32.4 39.2 36.3 29.6 9.7 27.6 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 2.3 2.2 2.3 5.3 2.5 2.1 2.9 2.4 2.3 1.7 2.6 2.0 11.7 6.4 11.5 6.2 7.5 29.7 12.9 9.0 10.2 12.8 13.9 12.4 1.0 10.0 8.8 1.8 16.7 9.1 11.1 21.2 0.0 8.1 5.6 10.1 11.6 12.7 11.4 10.8 5.4 26.5 12.8 10.5 36.2 13.7 12.7 11.9 6.8 20.1 9.5 16.8 5.3 36.2 12.2 8.4 10.3 9.7 13.4 8.8 1.8 5.6 8.2 7.8 9.2 1.0 6.7 19.6 9.5 8.2 9.3 23.9 13.5 3.3 12.7 10.7 0.0 11.2 9.1 9.0 11.9 14.0 34.8 9.3 9.8 13.1 20.8 19.7 ZNF599 FLJ30663 ENSG00000153896 "Zinc finger protein 599" Q96NL3 19 34758073-34773229 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 33.2;Early spermatids: 81.4;Late spermatids: 30.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014701 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" Nucleoplasm "HPA014701: AB_1859371" "unprognostic (3.52e-3)" "unprognostic (1.42e-3)" "unprognostic (1.99e-2)" "unprognostic (9.35e-3)" "unprognostic (9.20e-2)" "unprognostic (5.16e-3)" "unprognostic (3.95e-3)" "unprognostic (1.72e-2)" "unprognostic (1.70e-2)" "unprognostic (7.35e-3)" "unprognostic (1.77e-3)" "unprognostic (5.03e-2)" "unprognostic (4.42e-2)" "unprognostic (1.16e-1)" "unprognostic (1.00e-1)" "unprognostic (2.71e-2)" "unprognostic (8.12e-3)" 4.4 5.9 5.8 2.3 6.7 1.2 5.6 6.8 6.0 8.1 8.1 6.3 2.5 7.6 11.9 3.9 8.6 2.4 4.7 5.5 6.4 9.5 4.7 4.7 3.3 6.4 6.6 7.4 4.8 9.8 11.0 3.1 6.3 9.5 2.8 4.7 5.9 4.8 3.6 4.4 4.3 3.6 6.2 5.0 4.8 14.0 6.6 4.2 11.1 5.0 2.7 6.0 6.1 7.3 4.8 2.4 4.6 3.4 5.2 6.9 2.6 1.7 4.5 4.1 4.7 2.0 3.1 0.5 4.3 3.1 3.8 2.3 3.4 2.3 4.9 0.5 4.2 3.6 4.9 5.7 4.1 0.8 3.5 6.5 3.1 1.9 2.0 6.7 4.7 8.3 6.2 0.4 6.0 1.9 9.1 3.8 2.0 6.5 0.1 4.6 4.5 3.0 5.1 1.1 5.8 8.4 5.6 1.0 3.2 3.0 2.8 0.4 2.6 3.2 4.4 3.0 1.9 5.1 5.6 0.4 2.5 0.1 3.8 1.9 0.6 3.5 3.4 1.4 2.3 1.0 3.5 1.9 1.0 2.2 3.5 3.2 0.3 3.5 3.2 2.2 2.8 1.6 5.8 6.7 6.8 6.0 5.5 6.4 6.4 6.6 6.3 6.2 6.6 7.3 5.8 0.0 3.7 5.2 2.5 3.1 7.6 5.5 6.8 4.2 10.2 11.2 4.4 1.5 8.3 18.4 2.1 7.9 5.2 1.1 33.2 4.6 81.4 25.4 6.4 5.3 1.2 3.8 0.7 2.3 4.5 8.3 1.5 4.1 0.0 6.6 5.0 4.0 3.8 0.0 3.5 3.3 4.1 1.0 1.9 30.8 10.2 1.2 5.4 0.0 0.9 14.4 4.1 9.5 8.1 3.1 0.9 4.9 4.8 5.5 2.9 15.3 22.7 2.7 6.6 5.7 5.7 26.2 7.5 4.8 1.6 1.9 3.9 7.2 3.2 6.0 ZNF646 KIAA0296 ENSG00000167395 "Zinc finger protein 646" O15015 16 31074422-31084196 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 25.7" "Cell type enhanced" "Detected in many" "Early spermatids: 24.8;Spermatocytes: 16.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 25.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042364, HPA066468" Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane, Cytosol" "HPA042364: AB_10794796, HPA066468: AB_2732746" "unprognostic (1.61e-2)" "unprognostic (2.18e-1)" "unprognostic (8.08e-2)" "unprognostic (1.18e-2)" "unprognostic (4.66e-1)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.28e-6)" "unprognostic (3.23e-2)" "unprognostic (4.21e-2)" "unprognostic (6.96e-2)" "unprognostic (1.16e-2)" "unprognostic (9.83e-2)" "unprognostic (2.07e-2)" "unprognostic (2.65e-1)" "unprognostic (1.93e-1)" "unprognostic (1.07e-1)" "unprognostic (2.16e-1)" 5.6 4.1 4.4 6.7 4.9 9.2 5.0 6.9 5.9 5.8 1.6 5.0 6.4 6.5 2.5 5.2 5.5 3.5 4.8 3.7 2.9 4.9 4.3 4.7 7.1 6.2 4.7 6.2 5.6 4.4 5.0 4.0 4.9 5.4 2.8 1.6 6.2 4.0 7.9 8.0 6.4 3.2 3.5 8.0 5.5 25.7 5.8 8.6 5.1 3.7 5.1 5.4 4.9 6.3 7.8 15.8 10.2 8.0 7.1 5.5 13.7 8.3 8.8 9.8 9.0 11.6 7.1 15.0 13.0 7.1 6.5 10.2 8.5 9.2 3.7 17.2 8.1 11.1 15.6 9.7 7.4 14.4 16.7 7.1 8.1 10.6 6.0 7.6 5.9 12.5 18.2 8.5 7.5 12.2 16.0 9.9 13.8 3.5 8.1 25.5 20.2 15.3 3.1 7.3 14.7 14.9 9.5 10.0 4.9 4.4 8.4 12.5 12.1 12.3 7.0 8.2 7.8 14.2 14.1 14.9 11.2 15.5 9.8 9.8 4.5 13.2 5.1 4.2 2.6 3.9 2.4 2.1 4.6 4.4 2.7 3.0 25.1 4.8 2.8 6.6 2.6 2.1 4.4 4.9 6.9 5.9 3.7 2.9 6.2 4.7 4.9 3.5 5.8 6.3 4.7 3.2 1.3 3.6 4.2 3.3 1.0 2.6 2.8 3.6 3.4 3.4 1.7 1.5 2.2 1.8 4.2 1.9 6.6 6.6 1.9 4.1 24.8 3.0 3.7 3.4 6.0 2.1 2.2 3.5 2.1 2.5 5.6 4.9 1.3 5.1 1.8 1.9 4.9 1.7 2.1 3.4 4.1 4.7 2.8 6.6 2.8 6.4 0.0 7.5 3.7 3.6 4.1 2.0 3.1 4.4 7.6 4.5 2.3 2.4 5.8 2.2 2.7 1.1 0.0 3.5 2.3 16.2 7.0 2.9 4.0 2.5 4.9 2.8 3.7 1.9 ZNF655 "VIK, VIK-1" ENSG00000197343 "Zinc finger protein 655" Q8N720 7 99558406-99576453 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029534, HPA050750" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA029534: AB_10603008, HPA050750: AB_2681225" "prognostic favorable (7.12e-4)" "unprognostic (3.03e-2)" "unprognostic (9.62e-2)" "unprognostic (5.00e-1)" "unprognostic (1.51e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.24e-4)" "unprognostic (2.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-2)" "unprognostic (1.12e-1)" 11.6 11.9 7.0 14.3 6.2 8.9 12.8 8.3 7.8 13.2 5.9 15.5 15.9 10.1 11.0 26.9 11.5 10.2 8.4 6.3 6.1 13.8 14.9 15.3 19.7 5.0 5.5 13.9 21.1 14.4 8.2 12.5 6.4 11.4 11.8 8.5 16.7 11.3 12.7 18.4 13.8 11.7 5.1 14.2 18.0 7.4 6.3 22.6 11.8 13.5 17.3 18.8 14.9 9.6 40.5 35.9 16.5 23.9 15.8 25.4 12.4 24.0 45.8 40.7 37.8 20.1 37.0 31.8 0.4 33.2 52.0 25.2 18.0 29.6 40.6 34.5 23.6 18.9 16.0 27.8 24.1 38.1 35.9 21.1 32.8 35.8 50.6 21.4 17.3 26.4 54.4 39.7 24.4 0.1 53.9 36.6 21.1 0.1 0.0 19.9 14.0 52.9 25.9 42.8 17.4 37.6 25.1 0.7 27.2 24.0 12.2 20.2 13.3 24.3 60.2 43.4 43.6 47.3 72.7 63.4 23.5 18.2 39.9 147.8 43.2 74.4 47.8 47.2 45.1 32.7 44.1 55.7 40.3 31.3 35.0 43.8 50.3 37.0 55.2 23.3 61.3 55.4 7.0 6.2 8.3 7.8 6.3 6.1 5.0 5.5 6.4 5.1 6.3 9.6 19.5 96.1 82.8 51.2 53.2 44.7 46.5 36.5 42.1 48.8 34.4 25.1 36.1 31.5 44.3 23.9 41.7 31.6 76.3 46.3 33.2 31.6 12.8 25.8 33.9 20.4 41.5 12.8 53.4 36.2 42.7 32.7 37.2 33.0 18.9 70.8 19.2 24.6 37.4 50.5 57.4 40.4 18.3 63.4 31.6 9.7 25.4 56.0 23.2 44.0 59.2 24.9 106.1 61.3 75.3 48.2 55.2 25.2 55.4 44.5 48.1 41.1 26.0 45.8 13.1 39.9 31.7 39.0 29.8 55.6 48.9 73.6 62.5 30.0 28.1 64.0 ZNF688 ENSG00000229809 "Zinc finger protein 688" P0C7X2 16 30569672-30572734 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 180.3;Late spermatids: 576.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048922 Uncertain Approved "Nucleoplasm,Plasma membrane,Cell Junctions" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 80: Striated muscle - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 31: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Cell Junctions" "HPA048922: AB_2680557" "prognostic favorable (5.90e-4)" "prognostic favorable (7.74e-4)" "unprognostic (1.68e-1)" "prognostic favorable (4.58e-5)" "unprognostic (1.37e-1)" "unprognostic (1.76e-2)" "unprognostic (4.01e-1)" "prognostic favorable (3.24e-4)" "unprognostic (1.11e-1)" "unprognostic (3.26e-2)" "prognostic favorable (6.61e-4)" "unprognostic (7.75e-2)" "unprognostic (5.14e-2)" "unprognostic (7.08e-2)" "unprognostic (2.48e-1)" "unprognostic (4.12e-2)" "unprognostic (4.03e-2)" 8.7 8.4 17.6 9.8 17.5 11.4 5.1 20.5 19.1 6.7 16.4 9.7 14.6 7.8 5.6 5.6 10.4 4.2 7.0 16.5 15.8 8.2 8.3 7.5 9.5 17.5 16.9 9.1 12.3 9.7 8.4 3.3 17.2 7.5 6.4 5.6 10.1 6.9 25.6 9.0 11.6 5.8 16.2 12.0 10.1 13.6 18.1 8.2 5.1 9.7 5.4 6.6 5.7 20.2 10.4 9.5 7.3 8.1 13.3 5.2 3.1 6.7 8.2 5.0 4.0 2.5 15.1 6.2 12.8 6.9 6.0 8.6 2.2 3.6 4.7 16.7 6.4 3.8 3.7 2.7 6.3 4.3 17.9 8.7 8.2 5.3 6.0 7.7 4.7 7.7 3.9 12.0 5.3 13.5 14.9 9.9 3.3 8.6 4.9 13.3 3.8 9.2 8.2 3.2 12.1 13.2 2.4 14.1 15.3 2.0 15.6 7.8 5.4 5.5 4.0 5.2 4.7 20.5 13.2 5.7 12.2 4.3 9.7 12.0 4.6 11.0 6.2 4.2 5.4 6.5 6.6 6.8 4.2 7.6 5.7 5.0 5.3 20.4 6.5 7.4 11.2 3.3 17.6 17.5 20.5 19.1 16.5 15.8 17.5 16.9 17.2 16.2 18.1 20.2 16.3 6.4 3.1 5.9 22.8 6.4 10.5 12.6 16.5 19.8 20.3 22.7 11.2 22.8 10.2 16.5 18.8 7.5 26.0 38.6 49.0 24.8 180.3 25.4 9.5 14.0 20.4 11.2 5.1 31.2 9.6 15.6 17.9 9.0 5.1 12.1 20.7 22.6 24.4 21.9 5.1 27.7 12.2 33.1 12.0 576.6 19.9 17.4 17.8 1.9 28.3 31.2 30.9 9.0 10.3 21.8 37.2 19.9 16.7 10.1 59.2 54.1 38.4 27.4 6.6 17.2 20.2 34.5 8.5 11.2 7.1 4.7 23.2 15.1 23.6 8.5 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7 ZNF717 "X17, ZNF838" ENSG00000227124 "Zinc finger protein 717" 3 75678660-75785583 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 35.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "K-562: 47.7" HPA044549 Uncertain Approved "Nucleoplasm,Nuclear bodies,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Nuclear bodies" "Plasma membrane" "HPA044549: AB_10964630" "unprognostic (2.49e-1)" "unprognostic (4.44e-2)" "unprognostic (1.52e-1)" "unprognostic (2.49e-2)" "unprognostic (2.61e-1)" "unprognostic (1.00e-1)" "unprognostic (2.18e-1)" "unprognostic (3.80e-2)" "unprognostic (3.20e-1)" "unprognostic (2.16e-2)" "unprognostic (2.36e-1)" "unprognostic (1.45e-2)" "unprognostic (3.60e-6)" "unprognostic (3.88e-2)" "unprognostic (2.08e-2)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" 5.1 5.7 7.6 3.3 9.6 2.8 7.3 7.7 9.5 5.7 4.4 5.1 5.7 5.9 15.4 5.4 7.2 4.5 5.9 7.2 8.1 9.9 7.9 4.6 4.8 9.0 8.5 7.9 8.9 8.3 9.3 5.0 9.2 6.7 6.6 7.8 7.2 4.7 4.2 9.9 5.2 4.2 8.5 7.1 7.4 8.2 8.7 4.7 9.3 4.4 7.1 5.8 5.4 12.3 11.4 5.8 5.2 3.6 6.1 8.5 3.9 3.5 5.2 5.1 5.9 9.4 9.8 5.2 4.6 6.0 5.0 6.3 6.8 4.5 4.2 0.5 7.0 8.6 9.4 0.9 15.9 0.5 8.6 10.4 4.8 12.8 17.4 4.3 0.7 0.5 47.7 11.6 5.7 1.8 0.6 17.1 5.2 8.9 6.3 7.7 4.5 27.0 7.6 3.8 4.2 17.4 3.5 6.6 14.6 5.1 16.8 4.6 1.6 9.3 10.9 6.4 1.4 12.0 19.9 5.2 4.7 1.3 6.0 1.3 2.6 5.1 2.1 3.8 1.2 5.1 3.3 2.0 2.7 6.1 6.3 3.7 0.7 3.0 3.8 4.1 1.1 2.0 7.6 9.6 7.7 9.5 7.2 8.1 9.0 8.5 9.2 8.5 8.7 12.3 6.6 3.2 3.1 28.1 6.0 3.2 4.2 3.4 5.2 8.5 9.1 8.3 5.6 8.6 4.2 7.3 2.1 5.2 5.8 2.2 11.7 4.6 5.0 3.4 4.8 5.1 5.3 7.4 21.7 4.4 1.8 5.7 4.6 2.6 8.9 11.4 7.9 8.2 7.3 10.1 27.2 7.0 4.1 5.7 4.1 2.1 2.5 4.5 1.8 16.9 5.0 5.2 5.2 25.6 35.4 3.9 2.0 3.0 0.7 5.1 6.3 17.5 6.3 8.1 0.0 5.1 5.3 11.1 8.6 7.0 4.4 3.4 3.1 7.9 5.0 3.9 ZNF720 ENSG00000197302 "Zinc finger protein 720" Q7Z2F6 16 31713229-31794869 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA041570 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Nucleoplasm, Plasma membrane" "HPA041570: AB_10795126" "unprognostic (5.52e-2)" "unprognostic (2.30e-1)" "unprognostic (1.84e-1)" "unprognostic (8.30e-2)" "unprognostic (2.58e-1)" "unprognostic (2.48e-1)" "unprognostic (2.30e-1)" "unprognostic (1.82e-3)" "unprognostic (8.72e-2)" "unprognostic (5.94e-2)" "unprognostic (1.54e-1)" "unprognostic (8.91e-3)" "unprognostic (5.47e-3)" "unprognostic (3.70e-2)" "unprognostic (9.62e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-2)" 6.0 6.9 5.9 6.8 5.7 6.5 7.2 10.8 6.4 5.1 5.9 7.3 4.1 6.2 9.4 7.8 7.0 5.9 4.6 5.7 6.3 8.7 6.7 6.1 11.0 6.8 7.3 4.4 7.2 7.2 7.3 9.2 7.7 7.9 7.9 6.1 5.8 7.0 6.3 10.0 5.3 6.1 6.6 8.2 8.3 8.2 6.5 7.4 7.7 4.4 10.8 6.2 5.7 6.3 15.1 10.5 12.6 10.7 10.9 16.5 12.4 15.9 10.1 7.6 10.1 7.9 15.8 7.3 27.2 5.3 11.2 10.2 12.7 6.2 11.3 32.7 6.6 4.1 5.7 21.8 16.4 8.8 21.6 11.1 16.7 5.3 7.3 15.1 14.3 17.4 13.8 9.4 8.3 24.5 8.9 11.6 12.5 10.4 8.2 17.0 5.7 11.5 8.5 9.4 5.6 8.6 15.9 6.8 15.4 19.9 13.5 17.3 9.5 5.5 4.3 11.1 4.9 15.5 18.3 21.0 4.9 13.3 8.8 21.2 6.7 33.7 18.6 7.6 14.3 19.9 13.0 17.2 7.4 20.3 12.2 15.1 8.8 20.2 8.5 12.9 18.1 6.8 5.9 5.7 10.8 6.4 5.7 6.3 6.8 7.3 7.7 6.6 6.5 6.3 19.4 16.0 21.0 25.8 19.8 9.1 16.9 23.4 6.8 25.6 15.0 18.4 12.2 5.7 19.4 5.5 6.2 35.4 24.5 10.3 23.5 16.9 7.3 20.6 19.2 21.5 17.4 9.9 32.0 13.5 12.3 16.4 15.3 20.1 21.5 25.8 15.7 10.6 16.8 23.5 28.7 13.5 22.4 9.5 14.5 4.1 13.4 13.0 10.6 24.4 14.5 18.1 40.2 40.2 31.0 19.0 10.8 18.4 13.9 28.4 7.2 15.7 19.5 9.8 32.9 21.3 15.3 28.2 19.3 9.4 11.5 71.0 20.9 25.7 10.6 24.3 ZNF783 DKFZp667J212 ENSG00000204946 "Zinc finger family member 783" Q6ZMS7 7 149262171-149297302 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020375 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA020375: AB_1859453" "unprognostic (3.17e-3)" "unprognostic (2.54e-1)" "unprognostic (8.40e-3)" "unprognostic (1.16e-1)" "unprognostic (6.13e-2)" "unprognostic (1.08e-3)" "unprognostic (4.28e-3)" "unprognostic (1.05e-1)" "unprognostic (4.24e-3)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (3.29e-2)" "prognostic unfavorable (2.24e-7)" "unprognostic (2.49e-2)" "unprognostic (6.05e-2)" "unprognostic (1.61e-2)" "prognostic favorable (4.11e-4)" 7.1 5.4 6.6 5.3 6.5 3.0 7.4 6.6 7.4 10.8 5.0 7.7 4.0 8.9 3.6 6.0 10.1 3.0 5.4 6.2 6.6 9.9 3.4 6.2 7.3 7.1 6.6 11.7 7.1 2.9 7.1 2.9 6.7 9.4 3.8 2.9 5.8 4.0 6.4 7.0 9.2 4.5 6.1 12.8 6.6 6.6 6.8 4.0 8.3 3.3 6.4 8.1 7.8 8.0 3.5 3.5 5.7 4.1 3.7 6.9 5.3 2.1 1.1 5.0 2.2 5.6 6.5 11.9 5.5 3.5 1.1 2.3 4.0 4.3 2.2 3.3 3.5 7.6 8.7 1.1 8.5 5.1 9.2 7.4 8.7 4.5 5.5 3.1 3.4 4.2 6.2 6.0 4.2 7.6 7.6 7.8 12.8 8.1 4.7 1.6 0.5 10.6 5.6 5.8 4.5 9.5 8.5 4.0 6.0 3.0 4.4 10.1 5.0 4.0 0.9 2.1 4.9 9.1 6.2 0.1 5.6 1.8 8.7 0.1 0.4 0.1 1.0 0.7 0.8 0.7 0.6 0.6 0.4 1.3 0.8 0.7 0.1 0.5 1.7 0.9 0.4 0.4 6.6 6.5 6.6 7.4 6.2 6.6 7.1 6.6 6.7 6.1 6.8 8.0 6.7 3.2 2.7 5.5 6.1 2.5 2.5 4.6 1.8 13.3 7.5 7.6 2.2 7.2 3.2 0.0 10.4 3.0 6.1 3.4 3.9 2.1 5.3 3.2 7.9 4.3 3.6 1.7 5.7 2.7 2.0 7.0 7.1 6.2 0.0 6.4 5.0 6.6 4.2 6.7 6.3 4.7 4.1 7.9 4.6 5.0 8.7 3.9 5.4 11.2 5.2 3.8 8.2 4.0 8.5 3.0 1.6 5.7 3.9 4.0 3.0 1.1 5.5 8.8 13.1 7.4 5.0 16.3 6.9 3.6 3.0 1.1 5.0 6.9 4.3 2.4 ZNF79 pT7 ENSG00000196152 "Zinc finger protein 79" Q15937 9 127424374-127445372 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 5.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028977 Uncertain Approved "Nucleoplasm,Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 16: U-266 - Nucleosome" "Cluster 59: Non-specific - Transcription" Cytosol "Nucleoplasm, Plasma membrane" "HPA028977: AB_10602359" "unprognostic (4.56e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "prognostic favorable (6.83e-5)" "unprognostic (2.84e-2)" "unprognostic (2.45e-2)" "unprognostic (2.11e-1)" "prognostic favorable (5.96e-4)" "unprognostic (3.41e-1)" "unprognostic (1.13e-2)" "prognostic favorable (5.42e-5)" "unprognostic (4.53e-3)" "prognostic favorable (6.04e-7)" "unprognostic (6.09e-3)" "unprognostic (5.01e-1)" "unprognostic (5.23e-2)" "unprognostic (1.32e-1)" 2.6 3.6 2.1 3.3 2.7 3.4 3.6 5.6 2.5 3.1 2.6 3.6 2.6 3.5 4.4 2.9 4.0 2.0 3.2 2.0 2.7 2.9 3.3 2.9 4.1 2.8 2.3 3.8 2.9 4.9 2.6 3.0 2.2 3.5 3.5 3.1 3.4 3.4 4.7 3.6 2.8 3.7 1.6 3.7 3.0 6.2 2.4 5.5 3.8 5.2 4.7 4.3 2.2 2.9 2.5 5.0 6.5 3.9 7.1 4.2 18.2 6.1 7.4 7.2 8.2 5.3 2.3 5.4 2.4 4.6 9.5 7.7 4.9 7.5 5.7 5.4 3.2 3.7 8.4 6.0 8.4 8.9 5.7 4.2 8.3 8.9 7.2 4.6 7.5 6.1 6.4 7.9 6.9 5.5 7.0 3.3 5.2 6.2 6.4 5.7 9.0 7.7 3.1 3.6 7.4 5.0 11.7 5.9 3.5 5.6 7.9 5.0 5.3 4.6 4.2 4.6 4.8 10.5 24.1 6.8 5.9 2.7 7.8 2.2 3.3 5.1 6.0 4.1 6.7 5.1 3.9 7.6 4.7 5.8 5.2 5.7 4.5 7.2 2.8 4.9 5.5 3.6 2.1 2.7 5.6 2.5 2.0 2.7 2.8 2.3 2.2 1.6 2.4 2.9 0.8 0.0 0.5 2.6 2.4 1.5 1.2 0.8 1.8 0.8 1.0 0.9 2.5 2.8 1.7 0.0 0.0 2.0 0.9 0.9 1.9 2.0 4.5 0.4 1.9 1.1 0.0 4.8 3.1 0.6 0.6 1.2 2.6 0.5 0.0 1.1 1.1 1.2 2.1 1.7 3.2 0.5 0.0 0.8 1.2 4.7 0.6 0.6 0.0 1.0 0.1 0.9 2.1 4.0 2.9 0.5 0.3 1.9 3.0 0.7 0.9 1.0 0.7 1.2 0.0 0.4 1.3 5.8 1.6 2.3 1.0 2.6 1.5 1.3 1.1 0.9 ZNF839 C14orf131 ENSG00000022976 "Zinc finger protein 839" A8K0R7 14 102317377-102342702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020434 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA020434: AB_10669862" "unprognostic (7.83e-2)" "unprognostic (1.96e-1)" "unprognostic (2.28e-1)" "unprognostic (8.81e-2)" "unprognostic (1.49e-1)" "unprognostic (2.33e-1)" "unprognostic (6.73e-2)" "unprognostic (5.69e-2)" "unprognostic (1.85e-1)" "unprognostic (7.10e-3)" "prognostic favorable (4.57e-4)" "unprognostic (2.40e-2)" "prognostic favorable (5.00e-4)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 7.6 9.3 9.7 6.8 8.9 11.5 13.7 6.2 9.5 9.2 7.9 7.8 7.1 8.1 9.3 7.2 17.0 6.8 8.7 8.9 11.0 11.3 14.6 6.1 10.8 8.7 8.6 10.9 12.1 10.8 9.2 5.6 8.1 9.0 8.1 8.0 10.5 9.5 18.5 19.4 9.8 5.2 6.7 15.1 8.0 31.3 9.3 12.2 11.2 12.1 8.8 7.0 6.0 8.7 13.5 12.1 15.4 27.8 7.0 11.8 26.2 10.3 8.4 12.6 10.3 4.6 11.2 13.8 8.3 7.0 5.2 13.0 10.0 25.9 9.7 18.6 19.1 9.6 12.7 7.7 6.3 9.1 8.1 9.5 18.9 24.4 22.6 19.1 17.0 19.3 21.0 17.6 17.9 25.1 13.9 14.6 20.6 7.3 12.0 29.7 9.4 8.8 11.2 10.9 8.2 25.7 8.5 10.7 9.6 14.5 24.5 14.7 6.7 8.1 7.3 11.3 9.3 17.3 13.5 16.2 6.3 10.7 13.6 0.0 0.2 0.7 0.6 0.6 0.7 0.5 0.4 0.4 0.3 0.4 0.7 0.6 1.0 0.1 0.1 0.6 0.6 0.1 9.7 8.9 6.2 9.5 8.9 11.0 8.7 8.6 8.1 6.7 9.3 8.7 4.6 0.0 10.0 12.1 4.1 3.1 2.6 2.2 2.8 7.6 6.7 7.1 1.9 7.2 3.7 11.0 8.4 6.3 6.5 3.3 11.7 2.9 27.4 6.1 4.3 3.5 1.2 7.4 7.9 2.8 3.1 4.0 5.6 4.5 3.8 10.6 4.6 4.7 3.1 3.3 7.8 5.7 4.1 2.2 1.5 3.8 5.0 3.5 3.6 3.7 1.9 6.9 1.0 5.0 8.2 2.8 1.6 4.1 4.5 2.5 5.3 7.0 7.9 9.6 0.0 3.6 3.3 19.9 11.6 3.7 2.6 5.6 4.5 5.7 5.4 1.5 ZSCAN22 "HKR2, ZNF50" ENSG00000182318 "Zinc finger and SCAN domain containing 22" P10073 19 58326994-58342332 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEK 293: 14.7" "Low region specificity" "Detected in all" HPA006471 Uncertain Uncertain "Plasma membrane,Actin filaments,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 15: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "Actin filaments" "HPA006471: AB_2221026" "unprognostic (5.55e-3)" "unprognostic (2.24e-1)" "unprognostic (6.56e-2)" "unprognostic (1.13e-1)" "unprognostic (1.93e-1)" "unprognostic (3.82e-2)" "unprognostic (2.47e-3)" "unprognostic (1.52e-1)" "unprognostic (2.91e-1)" "unprognostic (1.15e-1)" "unprognostic (2.15e-3)" "unprognostic (5.00e-2)" "unprognostic (7.59e-2)" "unprognostic (2.59e-2)" "unprognostic (1.74e-1)" "unprognostic (5.22e-3)" "unprognostic (1.07e-1)" 1.2 1.5 1.4 1.3 1.7 0.7 1.1 2.9 1.6 1.7 1.0 1.5 1.2 1.5 0.8 1.8 1.3 0.7 1.2 1.3 1.4 1.3 2.4 1.1 1.2 1.4 1.2 1.5 1.4 1.6 2.6 1.2 1.4 1.4 0.9 0.8 1.2 1.0 1.1 2.3 1.3 1.2 0.8 1.4 1.4 1.2 1.2 1.1 1.3 1.0 1.4 1.5 1.5 2.8 2.4 4.2 2.3 3.5 2.6 1.6 2.4 2.0 1.0 1.2 1.1 2.3 1.7 1.9 1.3 1.6 1.5 1.8 3.3 2.2 1.3 3.0 14.7 4.1 4.2 2.1 2.1 3.3 4.2 1.8 2.2 2.6 2.7 2.2 1.8 1.9 4.1 3.6 2.1 1.9 1.6 1.5 2.0 3.0 4.8 2.2 3.6 3.3 1.2 3.1 3.6 2.6 3.0 4.0 2.0 1.8 1.9 2.3 1.8 6.5 1.9 1.6 3.5 3.6 5.3 1.4 2.6 2.2 2.3 0.0 0.8 1.0 2.0 0.7 1.3 0.8 1.1 1.6 1.1 1.0 0.9 1.0 0.2 1.2 0.9 0.5 0.9 1.0 1.4 1.7 2.9 1.6 1.3 1.4 1.4 1.2 1.4 0.8 1.2 2.8 1.1 0.0 4.1 1.6 1.5 1.8 0.6 1.0 0.0 0.7 1.3 0.9 0.6 1.5 1.6 1.8 0.0 0.9 0.8 0.4 1.9 0.9 0.3 1.1 1.2 0.9 0.0 1.7 2.1 0.6 0.9 1.1 1.1 1.6 0.0 1.1 0.0 1.3 0.5 1.7 2.1 0.5 0.0 0.8 0.8 0.0 2.1 2.3 1.8 0.0 1.3 0.5 0.0 1.0 2.2 1.1 1.6 0.4 1.1 0.9 0.8 0.6 1.1 0.7 0.0 1.7 0.8 4.3 1.9 1.1 3.7 0.7 1.2 0.9 1.0 0.4 ZSCAN29 "FLJ35867, Zfp690, ZNF690" ENSG00000140265 "Zinc finger and SCAN domain containing 29" Q8IWY8 15 43358172-43371025 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 3.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007241, HPA011109" Enhanced Approved "Nucleoplasm,Plasma membrane,Actin filaments" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane, Actin filaments" "HPA007241: AB_10600420, HPA011109: AB_10611525" "unprognostic (3.90e-2)" "unprognostic (2.70e-1)" "unprognostic (1.15e-1)" "unprognostic (4.06e-2)" "unprognostic (2.21e-2)" "unprognostic (2.02e-2)" "unprognostic (1.57e-1)" "unprognostic (5.25e-1)" "unprognostic (2.12e-2)" "unprognostic (4.77e-3)" "unprognostic (1.64e-1)" "unprognostic (1.44e-3)" "unprognostic (9.61e-2)" "unprognostic (1.30e-1)" "unprognostic (1.31e-1)" "unprognostic (8.33e-2)" "unprognostic (3.43e-2)" 6.3 5.6 7.9 8.6 10.1 5.6 6.8 8.1 7.4 7.2 8.1 7.6 8.8 8.9 5.2 7.2 6.4 6.0 5.5 6.6 7.4 5.7 6.9 6.9 10.7 9.3 9.7 7.4 11.4 7.7 5.5 8.1 8.9 6.8 7.6 13.6 8.5 6.5 9.7 5.8 9.9 6.4 7.7 9.0 8.8 17.3 8.5 10.7 7.2 8.5 10.4 6.6 6.0 10.3 11.7 12.5 28.9 17.9 10.0 10.5 15.6 9.0 13.9 15.6 16.2 19.7 8.1 11.4 14.7 11.1 12.6 33.7 21.5 11.0 13.9 29.6 11.8 25.1 20.5 15.5 11.1 17.3 21.2 9.3 19.0 10.6 14.9 11.0 8.0 17.3 23.7 13.5 12.7 7.4 16.7 14.2 14.5 17.1 9.6 25.7 16.1 14.0 9.1 13.9 20.6 22.2 13.9 22.5 10.4 14.5 15.8 26.6 9.1 18.3 14.4 14.0 16.4 25.8 38.4 21.6 10.7 16.9 14.1 0.4 0.3 3.1 0.4 0.4 0.3 0.8 0.4 0.3 0.4 0.5 0.2 0.6 0.7 1.0 0.3 0.3 0.8 0.3 7.9 10.1 8.1 7.4 6.6 7.4 9.3 9.7 8.9 7.7 8.5 10.3 3.5 6.4 7.9 6.8 5.8 3.6 2.6 3.7 4.6 10.8 4.8 4.8 7.8 4.3 7.8 7.3 27.1 5.1 7.1 11.0 0.0 5.4 81.7 5.0 8.2 4.9 6.1 1.3 6.4 7.1 4.4 5.8 9.7 7.8 0.0 6.5 3.9 7.2 5.8 13.5 5.2 8.1 4.1 10.6 3.7 20.7 6.8 4.8 5.4 9.4 6.7 5.5 10.3 10.1 10.2 8.7 5.0 6.0 3.3 3.9 7.7 2.6 5.2 18.0 0.0 4.9 3.8 12.0 6.7 4.4 3.1 3.8 4.2 2.8 7.0 2.4 ZSWIM1 "C20orf162, dJ337O18.5" ENSG00000168612 "Zinc finger SWIM-type containing 1" Q9BR11 20 45881227-45885266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041147, HPA046751" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA041147: AB_2677329, HPA046751: AB_2679785" "unprognostic (6.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (1.51e-2)" "unprognostic (1.69e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.47e-4)" "unprognostic (9.06e-2)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.77e-4)" "unprognostic (1.78e-1)" "unprognostic (2.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "unprognostic (4.64e-1)" "unprognostic (4.29e-2)" 3.0 4.1 2.7 3.7 2.6 6.0 3.5 4.6 2.9 3.1 2.7 4.1 4.6 3.4 3.5 3.5 4.2 3.2 4.9 2.7 2.5 3.6 1.9 3.3 5.0 2.6 2.7 5.8 4.2 4.9 1.1 4.0 2.5 4.1 3.5 8.2 4.9 3.4 15.9 6.5 4.4 3.5 1.9 4.6 4.3 3.8 2.9 3.9 4.5 5.1 4.9 3.4 1.4 3.1 7.2 8.6 6.4 7.8 11.2 6.3 6.5 4.8 5.9 10.2 9.3 19.5 8.4 8.4 13.9 6.7 11.2 17.0 10.1 12.9 7.7 3.4 6.1 10.7 11.5 14.0 6.8 9.2 10.9 9.2 10.6 8.6 8.2 7.8 7.9 7.3 9.8 6.7 6.0 20.8 10.0 7.9 3.6 8.1 9.7 7.8 9.1 6.0 6.7 10.1 8.6 5.5 16.2 24.0 5.8 5.7 14.6 7.2 7.0 11.5 7.3 6.4 7.0 6.6 5.0 8.2 9.2 6.8 6.0 2.4 1.4 3.6 0.5 1.8 0.3 2.4 1.7 0.7 0.7 2.2 2.3 2.1 1.6 0.6 1.8 2.2 1.4 0.8 2.7 2.6 4.6 2.9 2.7 2.5 2.6 2.7 2.5 1.9 2.9 3.1 0.8 3.2 2.7 0.7 1.4 1.1 2.4 2.4 2.2 3.0 0.8 0.5 5.7 4.3 1.2 0.0 0.0 2.9 0.3 4.2 3.9 2.4 0.6 1.1 1.7 1.7 2.4 4.4 0.8 3.8 2.8 1.9 4.1 1.5 3.8 2.5 2.5 2.1 1.7 6.7 0.9 2.8 2.0 1.4 1.9 0.7 3.4 0.7 0.0 0.0 1.8 1.6 1.0 0.0 0.8 3.3 3.7 1.5 0.5 1.6 2.4 1.2 0.4 3.8 0.0 2.0 1.8 1.0 2.0 1.4 1.6 2.3 1.8 3.6 3.0 2.0 ZSWIM8 "4832404P21Rik, KIAA0913" ENSG00000214655 "Zinc finger SWIM-type containing 8" A7E2V4 10 73785606-73801797 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041244 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA041244: AB_10794269" "unprognostic (8.83e-2)" "unprognostic (2.86e-1)" "unprognostic (2.89e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-2)" "prognostic favorable (5.61e-4)" "unprognostic (3.11e-1)" "unprognostic (1.64e-1)" "unprognostic (2.97e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-3)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (2.41e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" "unprognostic (2.52e-1)" 60.4 97.0 86.7 19.7 88.1 42.8 59.3 85.1 110.5 77.1 88.3 77.7 27.2 63.8 43.4 105.6 62.5 24.9 65.1 87.5 85.5 97.3 143.6 68.9 25.1 87.9 86.4 69.8 64.4 35.4 145.0 24.8 87.1 91.1 17.8 27.5 70.9 28.4 62.2 88.9 70.1 28.1 83.7 109.8 68.1 96.4 87.8 25.1 87.6 22.4 21.6 74.5 77.1 90.4 14.0 23.3 28.4 46.9 65.6 31.2 16.3 17.5 48.1 24.3 29.1 20.7 11.3 7.9 12.3 28.6 23.6 20.6 10.1 19.9 12.2 12.6 21.3 11.2 26.1 27.7 49.2 7.7 41.4 51.4 36.2 30.2 35.0 66.0 28.5 16.4 16.0 14.9 28.3 21.2 11.7 22.8 8.4 11.2 72.8 13.9 13.5 4.7 34.9 29.6 6.8 30.9 14.5 42.1 25.9 24.5 28.5 15.8 29.6 26.7 16.0 12.2 18.1 37.6 21.6 5.1 29.5 11.3 14.1 2.4 2.2 1.9 3.0 1.5 1.7 1.8 1.3 1.3 1.8 1.2 0.6 1.9 4.9 1.1 2.5 3.8 1.8 1.0 86.7 88.1 85.1 110.5 87.5 85.5 87.9 86.4 87.1 83.7 87.8 90.4 17.2 3.2 11.5 49.6 7.2 12.4 7.4 15.1 11.4 32.8 20.2 17.7 1.4 20.0 12.8 20.2 68.8 13.4 27.2 21.7 1.9 13.7 5.5 14.0 19.0 17.1 20.4 11.4 34.0 14.8 8.4 13.2 24.5 22.2 0.0 18.8 29.6 35.0 19.0 35.3 30.2 18.3 14.2 24.2 15.7 2.2 22.1 17.1 16.0 21.5 19.2 19.6 15.5 26.7 36.5 17.5 19.5 24.0 8.2 17.7 41.3 11.7 15.4 45.3 13.1 21.1 18.3 35.8 15.9 14.9 14.2 28.7 13.9 19.3 12.1 17.9 ZYX ENSG00000159840 Zyxin Q15942 7 143381295-143391111 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "endometrium 1: 596.6" "Cell type enhanced" "Detected in many" "Macrophages: 207.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 163.3" "Group enriched" "Detected in all" 4 "dendritic cells: 58.4;granulocytes: 163.3;monocytes: 83.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004835, CAB009321, HPA073497, CAB075747" Enhanced Supported "Plasma membrane,Actin filaments,Focal adhesion sites" NA NA 180000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Focal adhesion sites" "Plasma membrane, Actin filaments" "CAB009321: AB_2221290, CAB075747: AB_2665753, HPA004835: AB_1080771, HPA073497: AB_2686611" "unprognostic (1.96e-2)" "unprognostic (5.35e-2)" "unprognostic (2.36e-2)" "unprognostic (1.25e-1)" "unprognostic (1.44e-2)" "unprognostic (1.18e-1)" "unprognostic (2.21e-3)" "unprognostic (1.66e-3)" "unprognostic (2.60e-1)" "unprognostic (4.22e-1)" "unprognostic (1.98e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (7.92e-5)" "unprognostic (1.39e-1)" "unprognostic (8.12e-2)" "unprognostic (1.95e-1)" "unprognostic (6.72e-2)" 211.5 75.4 21.6 82.5 24.3 106.3 191.0 24.4 33.5 275.7 24.8 382.6 28.1 596.6 16.5 136.7 294.9 57.0 152.0 21.9 21.9 99.4 89.9 316.8 53.9 27.5 24.7 168.7 78.5 84.3 52.4 38.4 27.5 171.9 20.2 5.2 108.1 75.3 113.3 130.7 148.7 127.7 23.8 213.6 154.0 98.9 28.8 27.6 89.0 19.1 31.1 301.6 185.9 26.8 73.9 39.3 50.6 70.5 93.9 208.2 63.4 152.1 158.9 146.5 122.7 135.4 42.6 4.6 57.5 168.5 84.1 55.8 31.7 138.0 67.8 81.6 18.7 105.9 45.7 46.9 163.8 86.4 162.6 222.9 60.5 160.1 54.0 90.5 187.9 9.1 28.0 42.8 159.6 73.4 1.3 165.9 110.0 25.4 273.1 16.3 28.0 6.4 112.2 34.6 2.8 39.5 112.3 99.2 57.0 45.9 12.1 80.5 343.7 176.5 74.1 187.9 152.4 15.6 20.4 11.7 154.6 87.4 119.8 18.9 70.8 48.2 20.2 70.4 16.2 3.1 19.4 23.3 58.4 2.0 11.7 13.8 163.3 14.7 83.6 14.5 19.1 44.1 21.6 24.3 24.4 33.5 21.9 21.9 27.5 24.7 27.5 23.8 28.8 26.8 51.6 6.4 6.4 8.1 26.7 33.8 174.0 78.4 26.7 3.7 40.2 85.3 11.6 25.8 45.4 35.0 0.0 40.6 51.7 40.1 7.9 100.3 1.5 23.4 172.6 58.2 38.2 19.3 36.9 94.1 95.8 66.6 44.9 42.0 36.8 13.7 55.3 32.0 164.6 0.0 18.3 26.7 24.4 195.7 95.1 6.8 28.6 207.1 14.2 7.5 171.9 15.1 40.2 7.5 5.2 169.8 48.2 55.3 20.3 61.3 19.8 19.6 9.9 3.0 85.5 48.7 103.9 7.3 9.9 46.3 20.2 28.0 91.9 8.8 28.6 106.4