Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" ABCC3 "cMOAT2, EST90757, MLP2, MOAT-D, MRP3" ENSG00000108846 "ATP binding cassette subfamily C member 3" O15438 17 50634777-50692253 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 59.1;liver: 50.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 231.6;Distal enterocytes: 265.1;Gastric mucus-secreting cells: 271.7;Hepatocytes: 192.9;Paneth cells: 194.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.1;non-classical monocyte: 6.4" "Lineage enriched" "Detected in many" 5 "monocytes: 6.4" "Cell line enhanced" "Detected in many" "A549: 79.4;CAPAN-2: 60.6;HeLa: 36.9;OE19: 89.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB037136, HPA048483" Enhanced Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB037136: AB_477165, HPA048483: AB_2680414" "unprognostic (1.57e-2)" "unprognostic (1.60e-1)" "unprognostic (1.53e-1)" "unprognostic (1.65e-2)" "unprognostic (9.67e-3)" "unprognostic (6.19e-3)" "unprognostic (7.44e-3)" "unprognostic (8.20e-2)" "unprognostic (3.18e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (9.57e-4)" "unprognostic (1.60e-3)" "prognostic unfavorable (4.68e-6)" "unprognostic (3.42e-1)" "unprognostic (4.77e-2)" "unprognostic (4.44e-2)" "unprognostic (1.57e-3)" 3.1 59.1 0.1 3.4 1.8 0.8 4.2 0.2 0.7 2.1 0.0 18.9 12.0 1.1 1.8 7.5 1.0 11.9 0.9 0.3 0.3 8.0 50.4 4.8 1.9 5.9 0.8 0.7 22.6 0.8 0.8 1.1 3.5 5.9 8.7 0.4 7.0 5.5 0.2 7.1 11.9 1.3 1.7 3.4 17.1 1.0 2.5 0.3 5.5 0.0 1.7 6.3 3.6 2.4 5.7 79.4 0.0 0.3 4.4 6.9 0.1 10.4 13.1 0.7 0.7 4.2 60.6 0.0 8.0 20.6 14.5 14.5 0.0 1.0 1.0 0.0 0.0 1.7 36.9 24.2 17.2 0.0 0.0 7.5 5.6 2.9 6.2 8.5 1.4 0.0 0.2 0.0 8.0 18.9 0.0 0.0 0.1 89.7 10.1 0.1 0.0 0.3 33.4 34.2 0.1 0.6 19.2 3.1 0.0 0.1 2.6 0.0 17.3 0.5 3.4 0.2 8.5 0.1 0.0 0.0 8.2 0.0 0.9 0.2 2.3 0.0 0.0 5.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 1.0 0.3 6.4 0.1 0.5 5.4 0.1 1.8 0.2 0.7 0.3 0.3 5.9 0.8 3.5 1.7 2.5 2.4 0.7 19.2 5.5 0.0 1.8 9.4 122.2 47.1 42.7 1.6 1.9 6.9 3.1 231.6 19.5 14.7 0.0 0.4 0.0 265.1 5.9 100.1 82.9 5.9 8.8 2.7 23.5 0.0 4.3 106.1 3.7 3.6 271.7 30.5 0.0 3.1 3.9 192.9 26.1 1.7 0.9 96.2 12.2 33.0 11.4 118.6 9.0 31.6 3.6 2.8 8.7 2.9 1.0 0.5 0.5 105.9 194.7 3.0 2.1 104.6 57.2 10.8 2.7 0.3 0.0 1.9 5.6 0.9 0.8 12.7 10.5 1.0 2.6 0.1 111.0 118.4 AC004691.2 ENSG00000250424 "Novel protein, MINDY4 and AQP1 readthrough" 7 30852273-30923812 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019206, HPA030130" Approved Approved "Plasma membrane" NA NA "Plasma membrane" "HPA019206: AB_1844965, HPA030130: AB_10601565" "unprognostic (2.15e-1)" "unprognostic (3.12e-1)" "unprognostic (1.83e-1)" "unprognostic (1.66e-1)" "unprognostic (2.72e-4)" "unprognostic (5.13e-2)" "unprognostic (3.44e-2)" "unprognostic (2.15e-1)" "unprognostic (2.88e-2)" "unprognostic (3.76e-1)" "unprognostic (2.49e-1)" "unprognostic (3.71e-2)" 0.2 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.3 0.3 0.0 0.5 0.4 0.4 0.4 0.2 0.6 0.9 0.2 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.2 0.6 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.2 0.3 0.1 0.1 0.1 0.6 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ADAM12 "MCMPMltna, MLTN" ENSG00000148848 "ADAM metallopeptidase domain 12" O43184 10 126012381-126388455 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "placenta: 166.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 102.2;Extravillous trophoblasts: 400.8;Oligodendrocyte precursor cells: 99.0;Syncytiotrophoblasts: 129.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "MAIT T-cell: 6.1" "Lineage enriched" "Detected in single" 62 "T-cells: 6.1" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 154.2;hTEC/SVTERT24-B: 94.3;U-2197: 93.2;U-251 MG: 86.2;U-87 MG: 70.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA030866, HPA030867, HPA030868" Enhanced Supported "Plasma membrane" "Secreted in female reproductive system" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA030866: AB_2673636, HPA030867: AB_10602428, HPA030868: AB_2673638" "unprognostic (3.35e-1)" "unprognostic (1.05e-3)" "unprognostic (3.52e-2)" "unprognostic (2.47e-2)" "unprognostic (3.34e-2)" "unprognostic (2.16e-1)" "unprognostic (2.91e-6)" "unprognostic (2.17e-2)" "unprognostic (4.85e-2)" "unprognostic (1.30e-2)" "unprognostic (2.53e-2)" "unprognostic (1.09e-1)" "prognostic unfavorable (2.39e-14)" "unprognostic (3.11e-3)" "unprognostic (9.06e-3)" "unprognostic (4.70e-3)" "unprognostic (3.47e-3)" 11.4 0.1 2.0 6.0 4.0 0.1 4.6 1.6 2.1 18.2 3.5 0.4 0.2 6.3 0.0 0.4 0.2 11.8 0.7 1.0 2.5 1.0 0.2 1.3 3.2 6.0 2.7 8.8 0.5 0.1 1.1 166.5 3.1 0.3 0.6 0.3 1.1 0.0 0.1 0.4 0.5 4.3 1.8 1.6 0.5 0.9 10.4 1.8 0.3 0.0 3.5 11.6 0.5 3.0 16.8 2.5 6.5 0.1 18.7 38.3 0.0 42.7 3.5 14.2 35.5 0.0 0.0 0.0 0.0 154.2 30.0 0.0 0.2 1.4 15.5 1.9 0.6 0.2 25.1 0.0 2.9 0.0 33.2 47.0 0.0 94.3 2.9 27.1 0.0 0.0 0.0 0.2 11.8 0.0 0.0 0.0 0.1 0.0 2.8 0.0 4.8 4.4 0.4 44.1 0.5 28.4 5.0 0.0 0.7 2.5 0.1 0.1 0.0 50.9 16.9 93.2 86.2 0.0 0.5 0.0 70.7 0.1 32.3 0.0 0.0 0.0 0.3 0.0 6.1 0.0 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.1 2.0 4.0 1.6 2.1 1.0 2.5 6.0 2.7 3.1 1.8 10.4 3.0 0.5 0.0 1.9 22.5 0.3 1.5 0.4 3.0 0.0 2.1 1.7 3.6 2.3 0.0 0.5 0.0 102.2 14.0 0.5 0.7 0.0 8.0 10.9 10.7 16.6 1.6 0.0 0.0 7.4 1.1 400.8 34.5 0.5 1.8 49.5 7.8 2.5 0.2 15.5 6.7 19.0 1.0 4.1 0.6 3.1 1.7 16.8 0.8 1.8 14.0 9.0 3.3 1.0 99.0 52.2 2.2 0.1 0.7 0.3 1.0 0.7 0.4 6.5 30.5 0.0 5.1 13.4 6.0 5.0 0.0 0.6 129.2 4.7 28.1 0.9 0.5 ADAMTS1 "C3-C5, KIAA1346, METH1" ENSG00000154734 "ADAM metallopeptidase with thrombospondin type 1 motif 1" Q9UHI8 21 26835755-26845409 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Heparin-binding, Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "ovary: 314.4" "Cell type enhanced" "Detected in many" "Adipocytes: 365.2;Endometrial stromal cells: 235.3;Endothelial cells: 275.9;Extravillous trophoblasts: 240.8;Fibroblasts: 243.9;Sertoli cells: 210.4;Smooth muscle cells: 452.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 8 "gdT-cell: 4.5;NK-cell: 6.6" "Group enriched" "Detected in many" 56 "NK-cells: 6.6;T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 382.0;BJ: 451.4;hTEC/SVTERT24-B: 250.0;hTERT-HME1: 248.2;LHCN-M2: 295.3;RPTEC TERT1: 343.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "spinal cord: 35.6" "CAB016394, HPA031498" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 4100000 "Cluster 40: NK-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB016394: AB_626637, HPA031498: AB_2673907" "unprognostic (6.82e-2)" "unprognostic (1.35e-1)" "unprognostic (1.21e-1)" "unprognostic (1.64e-1)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.13e-4)" "unprognostic (1.03e-1)" "unprognostic (3.28e-1)" "unprognostic (2.37e-2)" "unprognostic (5.39e-2)" "unprognostic (1.75e-1)" "unprognostic (4.55e-2)" "unprognostic (9.70e-3)" "unprognostic (8.27e-3)" "unprognostic (1.12e-1)" "unprognostic (6.76e-2)" "unprognostic (1.57e-1)" 234.6 46.4 22.2 71.3 24.9 1.4 94.1 20.8 28.9 87.4 22.3 54.6 8.7 97.1 9.0 82.6 161.2 111.8 95.9 21.5 23.5 76.0 39.0 79.7 10.1 24.8 25.5 314.4 29.4 18.5 25.5 245.1 25.2 88.2 59.3 15.6 19.2 13.9 48.9 21.9 44.6 162.6 25.3 13.9 56.0 8.2 26.4 12.2 50.1 40.3 5.4 143.1 50.6 30.5 0.1 0.0 6.8 0.1 382.0 104.9 21.8 451.4 199.6 90.4 61.1 0.0 0.0 0.0 29.5 120.1 2.0 9.2 4.6 23.6 150.0 0.4 120.3 0.0 29.7 0.1 85.6 15.5 0.0 103.0 0.3 250.0 248.2 15.1 35.4 3.7 7.3 0.0 295.3 0.0 1.7 0.3 21.9 0.0 14.5 0.0 151.6 0.6 343.9 25.1 0.2 32.7 21.4 0.0 2.2 16.0 0.2 3.8 34.9 99.6 4.3 156.0 63.1 0.5 0.0 0.0 80.8 0.5 29.7 0.0 0.0 0.0 4.5 0.0 0.5 0.0 0.2 0.4 0.0 0.0 0.1 0.7 0.0 6.6 0.0 0.0 0.0 0.8 22.2 24.9 20.8 28.9 21.5 23.5 24.8 25.5 25.2 25.3 26.4 30.5 365.2 6.4 22.4 2.9 0.5 121.2 32.5 10.4 53.5 0.6 13.9 54.9 179.5 12.8 9.6 57.0 0.0 71.1 13.1 0.2 1.9 47.4 1.4 86.5 235.3 275.9 0.0 0.4 3.2 22.3 240.8 243.9 11.7 148.2 2.5 0.3 157.8 2.2 16.5 0.0 3.3 0.2 2.0 5.0 38.5 4.4 109.0 5.8 53.4 7.5 0.6 52.2 20.6 2.0 19.9 20.6 0.0 41.8 3.6 26.3 0.0 6.3 3.3 3.3 210.4 91.0 452.4 0.4 1.0 22.8 41.6 54.9 10.1 8.8 0.0 16.8 ADD3 ADDL ENSG00000148700 "Adducin 3" Q9UEY8 10 109996368-110135565 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 449.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.2;ASC TERT1: 292.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009797, HPA035696" Supported Supported "Plasma membrane" NA NA 260000 "Cluster 2: Granulocytes - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB009797: AB_2223583, HPA035696: AB_2674740" "unprognostic (2.66e-1)" "unprognostic (2.63e-2)" "unprognostic (1.46e-3)" "unprognostic (1.64e-1)" "unprognostic (2.65e-2)" "unprognostic (1.75e-2)" "unprognostic (1.57e-3)" "unprognostic (6.42e-2)" "unprognostic (5.73e-2)" "unprognostic (2.37e-2)" "unprognostic (7.58e-2)" "unprognostic (9.12e-2)" "unprognostic (2.34e-3)" "unprognostic (1.36e-1)" "unprognostic (4.03e-1)" "unprognostic (3.68e-2)" "unprognostic (5.92e-2)" 57.7 21.7 105.6 38.8 97.2 37.5 89.4 88.6 129.3 57.6 65.9 58.2 71.9 24.9 62.4 39.0 47.6 72.0 59.9 113.3 108.1 102.7 27.8 38.4 70.9 107.3 94.8 46.4 67.9 18.8 25.3 36.6 102.0 32.7 66.0 99.4 59.1 31.8 9.6 33.6 85.4 23.9 105.2 40.0 63.7 51.5 95.6 87.4 87.7 25.6 65.4 42.3 40.1 122.4 29.2 6.0 41.7 19.8 313.2 292.1 17.7 41.2 110.9 25.4 49.9 60.3 90.6 89.9 45.2 63.9 26.4 10.0 37.3 27.1 39.5 9.0 46.5 8.8 28.5 45.9 35.5 30.5 66.0 142.5 12.9 63.3 2.6 96.4 37.8 109.9 23.5 48.7 46.7 0.8 32.3 31.0 25.8 69.2 15.3 27.7 58.2 4.8 65.7 14.2 6.1 67.9 27.6 8.9 66.5 62.2 10.7 11.4 9.5 16.0 42.0 33.5 9.1 68.9 31.5 82.7 47.8 16.2 27.7 139.5 29.6 98.0 68.8 26.5 55.7 51.4 72.9 59.1 24.8 42.9 83.2 67.6 47.1 73.4 32.6 16.3 73.3 94.9 105.6 97.2 88.6 129.3 113.3 108.1 107.3 94.8 102.0 105.2 95.6 122.4 67.3 22.4 52.9 449.2 110.6 55.7 35.9 77.4 38.7 26.8 56.0 34.4 128.2 74.4 85.5 36.8 60.5 55.6 112.7 125.2 60.7 27.2 51.4 70.3 76.0 77.7 102.4 32.6 83.4 61.1 12.1 182.4 100.9 56.0 26.0 18.8 126.7 12.2 25.7 116.1 141.1 71.6 48.8 88.5 41.1 25.7 226.5 66.3 58.7 70.3 65.3 339.0 151.4 236.8 279.6 59.8 167.1 251.3 68.4 38.4 135.2 162.2 151.9 121.7 65.7 27.6 36.2 122.7 62.1 53.2 50.6 22.3 111.5 30.9 166.7 98.6 ADGRB2 BAI2 ENSG00000121753 "Adhesion G protein-coupled receptor B2" O60241 1 31727117-31764893 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 61.4" "Cell type enhanced" "Detected in many" "Astrocytes: 20.9;Bipolar cells: 16.0;Excitatory neurons: 55.7;Inhibitory neurons: 13.8;Oligodendrocyte precursor cells: 20.6;Oligodendrocytes: 13.2" "Cancer enriched" "Detected in many" 4 "glioma: 20.5" "Region enhanced" "Detected in many" "hippocampal formation: 61.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 37.7;SH-SY5Y: 25.1;T-47d: 29.5;U-2 OS: 27.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069175 Supported "Plasma membrane" NA NA 32000 "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA069175: " "prognostic favorable (6.46e-4)" "unprognostic (1.74e-1)" "unprognostic (7.98e-2)" "unprognostic (4.34e-2)" "unprognostic (1.90e-1)" "unprognostic (2.40e-1)" "unprognostic (8.17e-4)" "prognostic unfavorable (4.02e-5)" "unprognostic (2.31e-2)" "unprognostic (1.54e-2)" "unprognostic (1.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.80e-3)" "unprognostic (1.63e-1)" "unprognostic (1.23e-1)" "unprognostic (1.75e-3)" "unprognostic (7.98e-2)" 1.5 3.8 30.6 0.4 30.1 0.2 1.3 0.0 41.1 2.4 0.0 1.6 4.0 2.9 0.2 0.6 1.3 1.1 4.5 61.4 0.0 0.8 0.0 0.7 0.4 0.0 0.2 1.5 0.5 1.2 8.0 2.7 0.0 1.9 0.1 2.9 0.5 1.8 0.7 0.7 3.8 1.3 0.0 0.8 1.1 2.9 1.0 8.7 2.7 0.4 0.2 1.5 1.0 12.2 1.0 7.5 6.9 20.1 1.9 1.2 3.3 4.8 7.6 4.6 8.1 0.4 2.3 0.0 4.7 2.1 7.7 0.8 3.1 0.4 0.8 5.4 3.2 0.0 37.7 0.0 0.1 0.0 2.6 1.2 0.5 6.4 0.0 14.4 0.7 14.7 0.8 0.2 5.2 0.6 13.9 0.1 8.7 0.2 2.1 20.8 0.8 0.7 0.0 9.7 5.2 25.1 11.0 0.7 0.8 2.4 29.5 0.0 0.2 3.6 27.5 0.5 1.3 0.0 0.0 0.8 11.0 0.1 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.6 30.1 0.0 41.1 61.4 0.0 0.0 0.2 0.0 0.0 1.0 12.2 0.1 0.0 0.0 20.9 0.3 0.0 0.5 0.0 0.0 16.0 2.0 1.3 4.3 0.0 0.0 0.0 6.2 1.0 1.2 0.0 0.0 0.1 3.6 1.4 0.6 0.1 1.2 0.0 55.7 0.0 1.4 2.3 0.5 0.4 0.0 1.5 0.0 0.0 0.4 8.4 13.8 0.9 0.0 0.0 0.0 12.0 1.2 0.0 0.0 4.7 0.0 11.4 4.1 20.6 13.2 0.1 0.1 1.9 0.1 0.5 5.7 2.5 0.0 5.2 0.0 1.4 0.7 0.9 4.5 0.0 0.0 0.3 0.4 0.8 0.5 1.3 ADGRG7 "FLJ14454, GPR128" ENSG00000144820 "Adhesion G protein-coupled receptor G7" Q96K78 3 100609601-100695479 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 15 "intestine: 42.9;liver: 24.7" "Group enriched" "Detected in some" 4 "Hepatocytes: 23.9;Paneth cells: 14.0;Proximal enterocytes: 39.4" "Cancer enhanced" "Detected in some" "stomach cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "CACO-2: 1.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056451 Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA056451: " "unprognostic (1.65e-1)" "unprognostic (1.10e-1)" "unprognostic (2.79e-1)" "unprognostic (8.46e-3)" "unprognostic (1.26e-1)" "unprognostic (6.71e-2)" "unprognostic (9.37e-3)" "unprognostic (2.84e-5)" "unprognostic (1.17e-1)" "unprognostic (2.16e-1)" "unprognostic (6.77e-2)" 0.1 0.1 0.0 0.9 0.0 2.2 0.1 0.2 0.1 0.5 0.0 5.2 42.9 0.3 0.0 0.2 0.6 0.7 0.2 0.0 0.0 0.1 24.7 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 0.2 2.9 0.2 0.1 0.0 0.1 0.2 39.3 1.5 0.0 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.9 0.0 0.0 0.2 5.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 14.0 0.0 0.0 0.0 39.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 0.0 ADGRL2 "KIAA0786, LEC1, LPHH1, LPHN2" ENSG00000117114 "Adhesion G protein-coupled receptor L2" O95490 1 81306147-81992436 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 11 "Excitatory neurons: 902.7;Inhibitory neurons: 646.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 252.8;hTEC/SVTERT24-B: 130.3;NTERA-2: 100.0;SH-SY5Y: 168.3;U-2197: 118.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043447 Approved "Plasma membrane" NA NA 700000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA043447: AB_2678486" "unprognostic (2.54e-2)" "unprognostic (6.29e-3)" "unprognostic (2.57e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (3.22e-1)" "unprognostic (1.61e-1)" "prognostic unfavorable (9.92e-4)" "unprognostic (3.55e-2)" "unprognostic (9.84e-2)" "unprognostic (2.42e-1)" "unprognostic (7.81e-2)" "unprognostic (8.01e-2)" "unprognostic (1.61e-1)" "prognostic unfavorable (3.00e-4)" "unprognostic (2.76e-1)" "unprognostic (3.38e-3)" "unprognostic (1.41e-2)" 19.8 19.9 11.0 8.2 13.4 0.0 17.8 6.5 26.3 16.4 5.0 15.3 5.8 12.4 15.0 23.6 23.1 23.1 28.5 13.9 14.6 21.4 38.5 64.9 8.9 8.6 10.7 36.3 9.7 27.5 20.5 48.8 7.6 30.0 10.9 25.2 36.7 19.4 4.4 12.9 13.4 12.7 7.0 19.9 15.5 4.2 15.5 10.4 43.2 19.7 8.7 13.2 23.4 15.0 18.2 9.9 252.8 0.0 30.3 35.3 3.4 6.4 14.8 2.5 2.9 0.0 0.0 0.1 69.6 34.6 7.1 10.1 20.3 28.0 2.3 0.5 41.5 0.0 7.0 16.6 11.8 0.0 0.4 32.5 1.8 130.3 12.9 17.8 42.9 0.0 0.0 0.0 3.4 0.2 0.0 0.1 100.0 0.0 7.1 0.0 34.9 0.0 56.9 3.8 11.7 168.3 0.0 6.3 0.0 73.5 0.4 74.7 27.5 26.0 28.9 118.9 9.3 0.0 0.0 0.2 14.9 0.0 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.0 13.4 6.5 26.3 13.9 14.6 8.6 10.7 7.6 7.0 15.5 15.0 25.3 3.2 2.2 23.8 0.2 0.0 7.0 0.0 2.2 48.5 6.6 11.2 44.1 10.0 3.1 5.5 6.2 0.4 0.1 2.1 0.0 4.7 1.4 11.7 10.3 36.9 0.0 0.0 902.7 1.6 0.4 19.6 0.5 25.4 0.0 32.3 30.0 39.3 0.9 33.7 646.8 2.0 0.0 3.1 0.0 1.4 23.3 1.1 0.0 69.3 0.0 19.0 0.0 11.1 13.0 0.8 3.6 17.7 0.0 10.4 0.0 7.8 0.0 3.9 19.7 2.5 19.8 1.5 3.5 4.1 0.0 0.4 0.5 43.1 3.5 3.0 ADORA1 RDC7 ENSG00000163485 "Adenosine A1 receptor" P30542 1 203090654-203167405 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 54.8;testis: 21.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 18.1;granulocytes: 22.3;Muller glia cells: 44.4;Oligodendrocyte precursor cells: 35.2;Oligodendrocytes: 31.5" "Cancer enhanced" "Detected in many" "glioma: 24.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 40.3;MCF7: 24.4;RH-30: 65.4;RPTEC TERT1: 31.7;SK-BR-3: 35.2;U-138 MG: 20.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044383 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA044383: AB_2678921" "unprognostic (3.93e-3)" "unprognostic (8.16e-2)" "unprognostic (6.16e-2)" "unprognostic (2.38e-3)" "unprognostic (2.25e-2)" "unprognostic (2.34e-1)" "unprognostic (4.64e-2)" "unprognostic (4.17e-2)" "unprognostic (3.04e-1)" "unprognostic (4.80e-3)" "unprognostic (1.42e-1)" "unprognostic (2.98e-1)" "unprognostic (2.96e-3)" "unprognostic (1.54e-1)" "unprognostic (1.27e-1)" "unprognostic (4.13e-2)" "unprognostic (5.76e-4)" 3.7 0.2 31.9 1.6 34.6 0.0 4.6 28.6 33.8 1.0 0.0 1.0 1.0 1.2 0.6 1.1 1.2 0.9 11.4 29.6 23.0 9.3 0.4 1.7 0.6 35.7 35.0 0.3 13.2 8.0 1.9 6.8 41.8 1.0 0.6 4.8 6.4 0.4 1.7 4.6 1.2 0.4 23.6 6.3 1.0 21.4 54.8 0.4 2.2 2.5 0.5 1.6 0.7 41.5 0.3 3.0 0.6 0.2 0.2 1.6 0.2 2.0 3.0 0.7 0.4 40.3 0.7 0.0 8.9 7.3 4.8 0.1 0.7 0.0 0.2 0.0 1.1 0.0 0.4 0.0 0.6 0.0 0.1 0.9 0.0 0.9 0.0 6.4 0.0 6.4 0.0 0.1 6.2 24.4 0.1 0.0 10.2 0.0 0.0 0.0 65.4 2.3 31.7 0.0 0.8 0.7 4.4 35.2 0.5 3.6 2.0 1.0 0.0 20.9 10.6 0.0 11.7 0.0 0.2 0.0 10.5 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.9 34.6 28.6 33.8 29.6 23.0 35.7 35.0 41.8 23.6 54.8 41.5 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 1.1 9.4 6.9 3.1 7.2 0.0 3.7 0.0 0.1 0.1 0.1 0.0 11.7 0.1 0.0 0.4 0.3 0.0 0.0 18.1 3.3 1.3 1.1 0.0 0.1 22.3 0.8 0.0 0.0 0.9 0.0 2.9 0.0 0.0 1.0 1.0 0.5 0.0 0.6 1.8 1.9 0.2 44.4 0.0 35.2 31.5 0.5 0.0 0.7 0.0 0.0 0.0 3.0 0.0 1.6 0.0 0.0 0.6 0.1 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 ADRA1B ENSG00000170214 "Adrenoceptor alpha 1B" P35368 5 159865080-159973012 "Cancer-related genes, FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 36.9;liver: 11.4;lymphoid tissue: 11.6" "Group enriched" "Detected in some" 7 "Excitatory neurons: 41.5;Inhibitory neurons: 32.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 36.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 11.9;HaCaT: 5.8;TIME: 9.8;U-2 OS: 7.9;U-251 MG: 6.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA074416 Supported "Plasma membrane" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 38: EFO-21 - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA074416: AB_2686688" "unprognostic (4.93e-3)" "unprognostic (2.94e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (6.00e-5)" "prognostic unfavorable (6.98e-4)" "unprognostic (4.08e-3)" "unprognostic (1.67e-3)" "unprognostic (1.68e-1)" "unprognostic (6.12e-2)" "prognostic favorable (2.67e-4)" "unprognostic (2.28e-1)" "unprognostic (1.37e-1)" "prognostic unfavorable (1.40e-6)" "unprognostic (5.24e-4)" "unprognostic (2.54e-1)" "prognostic favorable (3.19e-5)" "unprognostic (1.59e-2)" 4.2 1.8 3.4 0.3 16.1 0.0 1.9 0.0 7.9 0.4 0.0 0.7 0.4 0.9 1.4 0.3 3.0 0.5 2.0 6.0 3.4 3.9 11.4 4.0 1.2 0.0 36.9 2.9 0.4 0.5 0.6 0.3 6.3 0.6 0.3 0.5 0.3 0.7 0.7 0.9 1.4 0.4 0.0 11.6 0.7 0.2 4.5 0.1 1.5 0.7 0.3 0.4 0.6 5.2 0.4 4.5 0.3 0.0 1.9 0.8 0.1 0.5 0.1 0.5 0.2 0.0 3.8 0.0 11.9 3.4 4.4 5.8 0.0 0.5 0.3 0.0 0.2 0.0 1.7 0.0 4.1 0.0 0.0 2.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.7 0.0 3.8 0.0 0.4 0.0 0.0 0.3 0.3 1.7 0.1 0.0 9.8 0.1 7.9 0.0 6.6 0.0 0.0 0.0 2.9 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 16.1 0.0 7.9 6.0 3.4 0.0 36.9 6.3 0.0 4.5 5.2 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.5 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 32.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.0 0.0 1.5 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AL355315.1 ENSG00000249967 "Novel protein" 10 97584374-97673910 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "tongue: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.2;EFO-21: 1.3;GAMG: 1.0;HBEC3-KT: 1.1;hTERT-RPE1: 1.9" HPA076857 Uncertain "Plasma membrane" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 38: EFO-21 - Unknown function" "Plasma membrane" "HPA076857: AB_2686817" 0.5 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.3 0.3 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.5 0.3 0.0 0.0 0.2 0.2 0.0 0.4 0.8 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.1 0.0 0.2 1.2 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.0 1.3 0.2 1.0 0.7 0.0 1.1 0.6 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.3 0.2 0.4 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALK CD246 ENSG00000171094 "ALK receptor tyrosine kinase" Q9UM73 2 29192774-29921586 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "brain: 10.9" "Group enriched" "Detected in some" 5 "Inhibitory neurons: 274.2;Oligodendrocyte precursor cells: 433.8" "Group enriched" "Detected in some" 5 "glioma: 1.0;melanoma: 1.5;ovarian cancer: 0.7;thyroid cancer: 1.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "SH-SY5Y: 31.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010694 Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA010694: AB_1078133" "unprognostic (4.96e-2)" "unprognostic (1.11e-2)" "unprognostic (1.45e-1)" "unprognostic (4.56e-7)" "unprognostic (7.17e-2)" "unprognostic (1.71e-1)" "unprognostic (9.07e-3)" "unprognostic (6.29e-3)" "unprognostic (1.18e-1)" "unprognostic (1.01e-1)" "unprognostic (2.67e-4)" "unprognostic (3.70e-2)" "unprognostic (2.06e-2)" "unprognostic (7.15e-2)" "unprognostic (1.98e-1)" "unprognostic (1.38e-1)" "unprognostic (3.61e-2)" 0.3 0.6 2.2 0.2 2.4 0.0 0.1 0.7 2.8 0.1 0.8 0.6 0.1 0.0 0.0 0.0 0.0 0.2 0.0 1.5 3.9 0.0 0.0 0.1 0.0 4.4 6.8 0.0 0.0 0.0 1.3 0.0 10.9 0.0 0.2 0.7 0.1 0.1 0.0 0.1 0.3 0.1 2.9 0.0 0.1 1.2 2.7 0.0 0.3 0.0 0.0 0.0 0.0 2.1 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 4.3 0.0 0.0 0.1 0.4 31.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 3.7 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.4 0.7 2.8 1.5 3.9 4.4 6.8 10.9 2.9 2.7 2.1 0.0 0.0 0.0 66.6 0.0 0.0 0.0 0.0 0.0 1.9 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.1 0.5 0.1 0.2 0.0 0.0 12.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 274.2 0.0 0.0 0.0 0.0 41.2 0.0 0.5 0.0 7.5 0.0 0.6 0.0 433.8 21.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.1 0.8 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 ALPG "ALPPL2, GCAP" ENSG00000163286 "Alkaline phosphatase, germ cell" P10696 2 232406844-232410714 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Cancer enhanced" "Detected in many" "endometrial cancer: 49.1;testis cancer: 64.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 33.9;HaCaT: 24.9;SuSa: 38.3" "CAB020698, HPA038764, HPA038765, HPA051699" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB020698: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.39e-1)" "unprognostic (6.63e-3)" "unprognostic (1.27e-2)" "unprognostic (2.89e-1)" "unprognostic (1.46e-1)" "unprognostic (1.26e-1)" "unprognostic (1.69e-3)" "unprognostic (1.65e-1)" "unprognostic (2.67e-1)" "unprognostic (6.72e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.7 0.0 0.0 0.0 0.0 0.7 33.9 0.0 0.0 0.0 0.0 24.9 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.3 0.0 38.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 ALPI IAP ENSG00000163295 "Alkaline phosphatase, intestinal" P09923 2 232456125-232460753 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 138 "intestine: 141.2" "Cell type enriched" "Detected in some" 8 "Proximal enterocytes: 290.1" "Cancer enhanced" "Detected in many" "liver cancer: 4.7;renal cancer: 3.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 13 "CACO-2: 4.8" "HPA038764, HPA038765, HPA051699" Supported Approved "Plasma membrane" "Intracellular and membrane" NA NA 130000 "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (1.01e-1)" "unprognostic (7.71e-2)" "unprognostic (4.14e-2)" "unprognostic (1.47e-1)" "unprognostic (9.57e-4)" "unprognostic (8.07e-2)" "unprognostic (1.71e-1)" "unprognostic (9.99e-2)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 141.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 128.1 0.6 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 33.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 290.1 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 0.0 ALPP "PALP, PLAP" ENSG00000163283 "Alkaline phosphatase, placental" P05187 2 232378724-232382889 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Hydrolase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "cervix: 17.8;placenta: 34.6" "Group enriched" "Detected in some" 4 "Alveolar cells type 1: 12.8;Glandular and luminal cells: 5.0;Syncytiotrophoblasts: 6.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 15.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HaCaT: 381.0;SiHa: 103.6" "CAB026327, HPA038764, HPA038765, HPA051699" Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB026327: , HPA038764: AB_2676194, HPA038765: AB_2676195, HPA051699: AB_2681577" "unprognostic (4.86e-2)" "unprognostic (5.19e-3)" "unprognostic (6.67e-3)" "unprognostic (2.60e-1)" "unprognostic (2.44e-3)" "unprognostic (1.26e-2)" "prognostic unfavorable (4.33e-4)" "unprognostic (1.44e-1)" "unprognostic (4.09e-1)" "unprognostic (2.12e-1)" "unprognostic (1.27e-2)" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 17.8 0.0 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 34.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.5 42.9 0.0 0.1 0.0 0.1 381.0 0.0 0.0 0.0 0.0 0.2 0.0 7.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 3.2 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 103.6 35.3 0.0 3.5 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 12.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 1.6 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.0 6.7 0.1 0.2 0.0 0.0 AMER2 "FAM123A, FLJ25477" ENSG00000165566 "APC membrane recruitment protein 2" Q8N7J2 13 25161679-25172288 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 114.8" "Cell type enhanced" "Detected in some" "Astrocytes: 99.3;Bipolar cells: 105.5;Cone photoreceptor cells: 81.3;Horizontal cells: 153.1;Muller glia cells: 313.0;Oligodendrocytes: 337.1;Rod photoreceptor cells: 112.1" "Cancer enriched" "Detected in single" 24 "glioma: 4.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "AF22: 3.3;SCLC-21H: 2.3;SuSa: 2.3;U-266/70: 5.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039458 Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA039458: AB_10795677" "unprognostic (1.69e-2)" "unprognostic (4.13e-2)" "unprognostic (7.43e-3)" "unprognostic (2.32e-1)" "unprognostic (3.00e-3)" "unprognostic (5.00e-3)" "unprognostic (7.28e-2)" "unprognostic (2.34e-2)" "unprognostic (5.90e-4)" "unprognostic (1.60e-2)" "unprognostic (1.20e-2)" "unprognostic (1.52e-1)" "unprognostic (1.13e-1)" "unprognostic (1.34e-1)" 0.2 0.1 36.7 0.0 72.0 0.0 0.0 37.9 52.2 0.0 2.3 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 41.2 37.7 0.0 0.0 0.1 0.0 58.9 49.1 0.0 0.0 0.0 4.1 0.0 41.9 0.1 0.0 25.8 0.0 0.2 0.2 0.1 0.0 0.0 36.8 0.0 0.0 1.2 49.1 0.0 0.0 0.0 0.0 0.0 0.0 114.8 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 36.7 72.0 37.9 52.2 41.2 37.7 58.9 49.1 41.9 36.8 49.1 114.8 0.0 0.0 0.0 99.3 0.1 0.1 0.0 0.0 0.0 105.5 0.1 0.1 1.1 0.0 0.0 0.0 81.3 0.1 0.0 0.1 0.0 0.0 2.3 0.0 0.6 0.8 0.0 0.0 21.3 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 153.1 24.4 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.8 4.7 0.0 313.0 0.0 28.6 337.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 112.1 0.0 0.2 0.0 2.8 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 ANK2 "CFAP87, FAP87, LQT4" ENSG00000145362 "Ankyrin 2" Q01484 4 112818032-113384221 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 165.7;retina: 191.2;skeletal muscle: 171.7;tongue: 150.5" "Group enriched" "Detected in many" 4 "Astrocytes: 1101.2;Bipolar cells: 376.6;Cone photoreceptor cells: 479.6;Excitatory neurons: 1282.0;Horizontal cells: 1431.8;Inhibitory neurons: 1060.7;Oligodendrocyte precursor cells: 497.1;Oligodendrocytes: 1351.0;Rod photoreceptor cells: 484.4" "Cancer enhanced" "Detected in many" "glioma: 10.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 29.2;ASC TERT1: 32.2;RH-30: 49.6;SH-SY5Y: 24.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008007, CAB015178, HPA035970" Enhanced Approved Supported "Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB015178: AB_2242828, HPA008007: AB_2667965, HPA035970: AB_2674893" "unprognostic (8.33e-2)" "unprognostic (9.47e-2)" "unprognostic (1.33e-2)" "unprognostic (7.63e-2)" "unprognostic (2.73e-1)" "unprognostic (1.71e-1)" "unprognostic (1.54e-1)" "unprognostic (2.15e-2)" "unprognostic (1.23e-1)" "unprognostic (1.63e-1)" "unprognostic (1.79e-3)" "unprognostic (2.94e-2)" "prognostic unfavorable (2.41e-6)" "unprognostic (1.18e-2)" "unprognostic (3.16e-1)" "unprognostic (1.51e-3)" "unprognostic (2.04e-3)" 31.0 13.6 94.9 11.2 109.0 0.1 18.3 63.1 165.7 31.6 0.0 30.1 8.5 15.8 5.9 12.9 9.6 22.5 119.5 103.9 77.5 110.1 2.4 7.2 9.2 130.2 61.1 27.3 3.2 1.2 19.3 2.1 119.5 7.8 11.4 191.2 6.7 13.3 171.7 8.7 12.7 24.9 51.9 28.3 8.3 9.4 84.8 4.4 9.6 150.5 7.2 9.5 12.3 116.2 0.1 2.9 18.7 5.2 29.2 32.2 0.1 1.5 3.4 0.9 2.6 4.2 0.0 6.9 2.1 5.9 4.1 0.1 11.0 0.6 1.0 2.3 7.3 4.0 0.0 2.9 1.7 1.9 1.2 15.2 3.0 1.2 6.0 3.9 0.0 0.4 0.0 9.3 5.8 0.3 0.2 0.1 9.4 0.1 2.0 0.7 49.6 0.0 0.2 0.0 13.6 24.1 0.2 0.7 8.1 11.7 0.1 1.1 0.0 4.7 2.2 0.4 3.0 6.8 1.8 0.9 20.1 0.6 7.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 109.0 63.1 165.7 103.9 77.5 130.2 61.1 119.5 51.9 84.8 116.2 6.9 0.0 3.9 1101.2 1.1 10.5 0.0 0.0 1.8 376.6 0.2 0.6 188.5 0.0 1.3 20.2 479.6 0.1 0.0 0.0 15.6 0.0 111.2 36.4 6.0 6.4 66.0 0.0 1282.0 1.6 0.1 79.0 2.0 7.2 1.3 81.8 0.0 0.4 1.0 1431.8 1060.7 0.4 8.2 0.0 19.7 49.8 36.4 2.9 17.8 90.9 0.6 44.5 0.0 497.1 1351.0 0.1 5.0 30.1 0.9 0.4 0.1 127.9 0.8 484.4 6.6 24.3 26.5 2.3 1.5 0.8 9.5 0.0 1.9 2.6 0.3 0.2 ANK3 ENSG00000151150 "Ankyrin 3" Q12955 10 60026298-60733490 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Autism spectrum disorder, Cancer-related genes, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 490.2;Excitatory neurons: 859.2;Inhibitory neurons: 881.3;Oligodendrocyte precursor cells: 592.6;Oligodendrocytes: 1579.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RT4: 50.3;SK-BR-3: 49.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013249, CAB015179, HPA038455" Enhanced Supported "Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB013249: AB_2533145, CAB015179: AB_633909, HPA038455: AB_2676020" "unprognostic (1.91e-1)" "unprognostic (5.33e-3)" "unprognostic (6.76e-3)" "unprognostic (1.94e-1)" "unprognostic (1.13e-1)" "unprognostic (3.70e-3)" "unprognostic (3.47e-1)" "unprognostic (1.62e-1)" "unprognostic (1.89e-1)" "unprognostic (1.21e-2)" "unprognostic (3.83e-1)" "unprognostic (2.28e-2)" "prognostic favorable (8.88e-16)" "unprognostic (5.75e-2)" "unprognostic (2.59e-1)" "unprognostic (1.00e-1)" "unprognostic (2.83e-2)" 6.3 6.7 45.5 6.5 86.5 2.1 21.5 144.9 82.3 12.0 0.0 26.0 39.3 23.0 125.2 16.9 19.1 21.5 81.1 60.8 86.1 95.4 16.6 24.6 6.1 82.7 61.3 11.6 11.2 131.8 14.5 15.6 97.0 20.0 20.9 123.2 42.6 40.5 80.5 39.9 27.2 13.2 21.2 10.8 15.5 8.0 87.3 9.1 41.6 94.1 7.4 10.8 14.1 114.4 8.7 4.9 30.3 0.4 0.0 1.8 23.3 0.6 0.4 0.1 0.6 22.2 16.6 0.5 9.8 0.6 0.9 12.1 16.4 14.9 0.5 0.5 11.0 0.2 9.7 0.1 6.2 0.1 0.4 14.6 9.3 7.8 0.4 26.1 3.6 0.0 4.3 20.6 6.9 29.0 0.2 1.0 13.8 23.3 26.6 0.1 21.7 4.3 5.4 50.3 15.6 2.8 0.6 49.4 0.0 33.6 28.7 0.1 10.0 0.9 2.9 13.3 1.5 0.9 0.2 0.2 5.5 0.2 18.9 1.6 0.2 0.5 2.7 0.2 2.4 4.1 4.6 1.5 0.1 1.1 5.0 1.2 0.7 1.5 0.3 2.5 0.8 1.0 45.5 86.5 144.9 82.3 60.8 86.1 82.7 61.3 97.0 21.2 87.3 114.4 0.9 44.8 174.3 20.2 14.5 19.1 21.9 17.8 38.7 490.2 26.8 20.6 189.3 12.8 42.5 53.3 225.2 38.8 3.4 62.9 19.6 10.6 28.3 139.8 26.2 3.9 30.6 0.0 859.2 8.6 9.9 13.2 15.8 153.3 12.6 66.9 7.9 0.5 4.7 43.7 881.3 12.1 14.2 4.8 1.4 11.5 28.0 3.3 8.8 23.4 4.4 41.4 0.0 592.6 1579.5 4.8 41.8 5.7 3.4 12.2 62.5 51.3 66.7 216.6 0.0 30.2 11.7 1.1 2.3 35.9 18.2 25.0 18.5 4.5 17.8 18.4 ANKRD13A "ANKRD13, NY-REN-25" ENSG00000076513 "Ankyrin repeat domain 13A" Q8IZ07 12 109999186-110039763 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 160.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "fHDF/TERT166: 205.4;HBF TERT88: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039488, HPA043218" Enhanced Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA039488: AB_10673612, HPA043218: AB_2678367" "unprognostic (1.54e-1)" "unprognostic (3.94e-3)" "unprognostic (5.81e-1)" "unprognostic (1.62e-2)" "unprognostic (1.05e-1)" "prognostic favorable (7.70e-6)" "unprognostic (5.68e-2)" "unprognostic (1.31e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (6.77e-4)" "unprognostic (9.71e-3)" "unprognostic (1.67e-1)" "unprognostic (2.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.13e-2)" "unprognostic (1.08e-1)" "unprognostic (5.29e-2)" 13.2 10.9 6.3 36.5 10.0 36.0 16.4 8.8 8.1 14.1 6.1 21.8 14.3 11.9 6.6 31.7 12.3 22.9 10.7 7.1 7.4 17.6 15.3 26.9 54.0 8.4 8.7 16.3 12.3 17.4 4.6 24.4 9.0 17.9 22.4 8.7 27.5 24.6 6.9 22.6 17.6 24.4 7.5 32.8 17.1 60.9 8.4 27.9 28.2 8.7 66.7 25.9 13.2 15.0 163.7 7.3 16.9 15.6 25.4 25.1 20.8 160.9 150.5 149.8 79.3 21.2 10.3 107.8 12.4 205.4 18.7 19.0 21.7 24.0 200.3 122.3 19.2 39.9 15.6 17.4 22.2 46.8 46.2 21.9 24.9 63.8 36.5 37.3 23.0 24.9 31.6 17.2 66.5 5.8 41.3 19.5 9.3 11.7 34.1 35.8 47.3 42.7 21.2 20.7 34.7 16.5 29.6 57.0 19.5 11.4 26.0 38.5 29.2 111.6 20.0 62.2 87.4 36.8 23.3 144.1 54.3 31.7 16.5 1.5 1.2 5.6 0.5 2.5 1.5 2.0 1.3 0.6 1.5 1.2 0.7 1.0 3.5 0.9 1.1 1.0 0.6 0.7 6.3 10.0 8.8 8.1 7.1 7.4 8.4 8.7 9.0 7.5 8.4 15.0 15.7 48.1 32.5 13.4 75.5 29.3 18.7 11.0 15.4 24.4 23.1 16.9 13.0 28.6 30.5 57.0 14.6 16.9 31.2 30.3 21.5 29.2 104.7 22.0 12.3 14.9 18.7 19.4 15.9 17.6 21.0 15.5 16.3 29.5 13.3 18.5 15.7 17.3 15.4 25.2 26.9 9.4 4.1 37.1 26.9 160.4 11.8 33.7 14.2 16.9 34.2 9.7 21.6 17.6 46.0 20.8 12.5 21.8 33.0 16.2 16.0 9.8 37.6 14.2 32.9 50.3 18.0 71.1 15.0 23.9 37.8 37.6 31.8 16.9 17.0 25.7 ANPEP "CD13, gp150, LAP1, p150, PEPN" ENSG00000166825 "Alanyl aminopeptidase, membrane" P15144 15 89784895-89815401 "CD markers, Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation, Host-virus interaction" "Aminopeptidase, Developmental protein, Host cell receptor for virus entry, Hydrolase, Metalloprotease, Protease, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "intestine: 2384.1;pancreas: 675.0" "Cell type enriched" "Detected in many" 14 "Proximal enterocytes: 6315.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in all" 5 "cerebral cortex: 9.2;thalamus: 17.4" "Immune cell enriched" "Detected in many" 4 "neutrophil: 227.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 227.1" "Cell line enhanced" "Detected in many" "ASC diff: 613.7;ASC TERT1: 764.2;BJ: 738.4;BJ hTERT+: 1135.6;fHDF/TERT166: 703.8;HMC-1: 660.3;HSkMC: 670.0;HUVEC TERT2: 874.8;TIME: 815.1;U-2197: 891.4" "Low region specificity" "Detected in all" "Region enriched" "Detected in many" 5 "spinal cord: 14.8" "CAB002417, HPA004625" Enhanced Supported "Plasma membrane" NA NA 1200000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 56: Intestine - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002417: AB_563491, HPA004625: AB_2667199" "unprognostic (6.31e-2)" "unprognostic (7.94e-3)" "unprognostic (6.91e-2)" "unprognostic (2.16e-1)" "unprognostic (2.50e-1)" "unprognostic (1.13e-1)" "unprognostic (2.23e-2)" "unprognostic (1.89e-1)" "unprognostic (2.50e-1)" "unprognostic (7.73e-2)" "unprognostic (5.28e-3)" "unprognostic (3.96e-1)" "unprognostic (4.04e-3)" "unprognostic (3.20e-2)" "unprognostic (2.01e-2)" "unprognostic (4.61e-3)" "unprognostic (1.99e-2)" 55.4 7.0 1.6 36.6 1.6 103.4 55.9 1.3 9.2 41.4 3.4 266.8 2384.1 3.6 1.7 4.8 8.0 120.3 6.9 1.3 1.5 249.7 271.8 34.3 12.8 1.5 2.1 1.9 675.0 0.8 1.9 33.1 2.5 94.0 59.9 0.0 42.1 5.5 2.5 32.5 1970.6 29.7 1.3 25.9 8.0 2.0 17.4 7.1 8.2 3.8 4.7 16.8 15.0 1.2 0.1 45.6 0.0 0.5 613.7 764.2 6.2 738.4 1135.6 95.3 81.6 5.8 0.4 0.2 8.4 703.8 0.0 0.6 5.6 0.2 38.6 0.1 0.1 137.3 4.6 122.8 352.0 11.4 660.3 670.0 1.4 302.3 0.3 4.4 874.8 0.0 3.8 0.8 37.8 0.1 0.6 355.4 1.9 0.0 49.9 0.3 0.1 9.5 449.2 0.0 1.2 7.2 0.1 1.3 0.1 1.8 0.5 72.1 815.1 385.3 0.6 891.4 0.1 0.4 0.1 0.1 0.9 0.9 20.5 22.2 56.3 41.1 0.1 27.4 0.0 0.2 0.0 0.0 26.2 0.2 0.0 0.0 227.1 0.0 49.7 0.7 0.0 25.7 1.6 1.6 1.3 9.2 1.3 1.5 1.5 2.1 2.5 1.3 17.4 1.2 2.4 0.0 3.0 0.0 5.2 9.9 2.8 1.4 0.6 0.0 35.7 12.8 1.2 391.7 19.7 20.2 0.0 13.0 0.7 429.8 43.0 15.4 0.2 0.5 10.1 8.4 3.0 6.6 0.3 386.2 16.3 31.0 0.0 0.4 24.1 0.3 79.2 192.4 37.5 0.0 0.3 199.6 2.0 54.1 63.2 0.2 2.8 71.9 3.6 0.0 38.3 0.0 0.0 0.0 0.1 75.5 316.9 1.5 2.1 20.9 6315.2 435.0 3.3 0.0 26.3 0.8 8.1 0.3 0.5 0.2 5.8 6.4 3.7 187.8 290.9 1.4 ANXA3 ANX3 ENSG00000138772 "Annexin A3" P12429 4 78551747-78610451 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Phospholipase A2 inhibitor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 337.7" "Cell type enhanced" "Detected in many" "Adipocytes: 322.7;Alveolar cells type 1: 589.7;Ductal cells: 434.5;Exocrine glandular cells: 305.3;Pancreatic endocrine cells: 754.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 320 "neutrophil: 207.7" "Lineage enriched" "Detected in single" 327 "granulocytes: 207.7" "Cell line enhanced" "Detected in many" "A-431: 419.5;CACO-2: 403.5;CAPAN-2: 563.7;EFO-21: 334.7;hTERT-HME1: 566.3;OE19: 502.1;RPTEC TERT1: 477.8" "Low region specificity" "Detected in all" "HPA013398, HPA013431" Enhanced Supported "Plasma membrane" NA NA 6400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA013398: AB_1844861, HPA013431: AB_1844862" "unprognostic (2.66e-1)" "unprognostic (5.65e-3)" "unprognostic (4.92e-3)" "unprognostic (8.67e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-3)" "unprognostic (4.17e-2)" "unprognostic (1.87e-1)" "unprognostic (5.09e-2)" "unprognostic (2.10e-3)" "prognostic unfavorable (1.28e-4)" "unprognostic (4.82e-2)" "prognostic favorable (8.48e-6)" "unprognostic (2.23e-1)" "unprognostic (2.02e-2)" "unprognostic (7.20e-2)" "unprognostic (3.30e-2)" 52.9 3.1 16.5 22.7 17.3 337.7 43.8 14.5 28.2 19.6 11.7 27.7 15.8 12.5 3.7 55.2 16.8 17.3 51.2 14.2 21.6 24.9 3.9 144.4 2.4 19.9 16.1 2.5 32.7 34.0 5.9 81.5 20.8 68.0 26.7 1.6 119.5 12.9 28.3 10.0 13.3 20.1 14.6 21.6 90.5 1.9 19.9 7.1 83.7 36.7 12.7 10.2 15.6 14.7 419.5 77.7 1.3 0.9 1.0 0.9 0.6 4.9 0.4 11.0 10.9 403.5 563.7 0.1 334.7 14.4 0.4 161.6 0.1 300.0 16.0 1.4 3.3 36.4 142.0 23.9 45.9 5.9 0.2 2.4 262.6 4.1 566.3 60.1 118.9 9.0 0.7 0.3 1.9 15.9 1.7 0.2 13.0 502.1 55.4 0.0 0.8 0.0 477.8 45.2 0.3 0.3 235.5 58.2 16.6 186.1 9.9 4.3 153.2 0.6 52.6 0.2 93.0 3.1 5.1 2.2 0.0 0.4 0.1 0.6 0.2 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.4 0.1 0.0 207.7 0.1 0.6 0.1 0.0 2.9 16.5 17.3 14.5 28.2 14.2 21.6 19.9 16.1 20.8 14.6 19.9 14.7 322.7 589.7 47.3 0.0 1.1 24.9 81.8 144.9 1.8 0.2 27.6 85.9 8.6 55.8 175.2 38.6 0.0 212.6 1.0 35.4 17.6 434.5 1.1 33.7 4.4 84.6 5.4 3.2 0.9 305.3 106.2 16.9 99.9 58.1 5.1 0.1 23.2 0.6 18.9 0.0 0.3 33.4 122.1 0.3 0.3 0.3 3.1 6.9 5.4 42.2 21.0 1.2 0.0 1.0 0.6 754.2 61.6 0.4 0.6 158.6 11.5 5.5 89.6 0.4 0.0 7.6 18.7 1.1 0.6 21.9 6.7 62.8 2.3 1.3 29.7 46.7 AP2M1 "AP50, CLAPM1, mu2" ENSG00000161203 "Adaptor related protein complex 2 subunit mu 1" Q96CW1 3 184174689-184184091 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Endocytosis, Protein transport, Transport" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036849, HPA069870" Uncertain Supported "Plasma membrane" NA NA 7500 "Cluster 31: Non-specific - Inflammatory response" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA036849: AB_10672101, HPA069870: AB_2686217" "unprognostic (1.16e-1)" "unprognostic (1.35e-2)" "unprognostic (5.28e-3)" "unprognostic (4.96e-3)" "unprognostic (1.79e-1)" "unprognostic (2.88e-2)" "prognostic unfavorable (9.12e-4)" "unprognostic (3.80e-3)" "unprognostic (2.09e-1)" "unprognostic (5.53e-2)" "unprognostic (4.11e-2)" "unprognostic (9.18e-2)" "prognostic unfavorable (7.45e-6)" "unprognostic (2.61e-2)" "unprognostic (4.09e-2)" "unprognostic (1.60e-2)" "unprognostic (1.28e-1)" 191.8 364.2 233.5 164.7 250.3 231.3 164.6 211.3 257.3 222.8 196.3 232.4 167.5 216.4 104.2 218.1 178.6 166.5 366.2 261.1 249.0 196.0 140.9 180.0 148.2 234.8 211.1 198.6 106.4 224.8 224.9 243.3 248.9 183.2 141.1 230.4 167.2 231.8 181.2 157.2 156.2 243.7 200.9 162.5 156.3 106.4 235.4 158.4 148.0 194.0 157.6 223.7 192.4 225.6 436.3 327.5 275.7 311.8 432.1 450.8 284.3 714.3 412.5 788.5 550.5 355.1 309.9 198.2 851.3 1076.1 516.1 480.0 376.3 482.9 647.1 409.8 470.4 512.2 365.8 317.9 508.9 254.8 311.5 577.0 269.4 501.1 318.5 711.0 595.3 258.3 250.0 377.1 750.1 993.6 330.1 151.2 674.1 388.1 484.7 302.7 351.5 393.7 489.7 389.3 292.0 212.6 561.3 696.4 335.1 427.5 934.4 305.7 645.0 497.1 400.1 492.4 960.2 336.9 318.7 441.6 937.1 369.9 331.7 194.4 294.8 244.9 137.5 238.8 136.2 114.3 127.6 134.0 268.7 112.7 107.7 111.8 127.7 170.2 206.8 134.1 185.4 441.0 233.5 250.3 211.3 257.3 261.1 249.0 234.8 211.1 248.9 200.9 235.4 225.6 146.8 54.5 50.7 41.4 84.8 124.9 177.2 275.1 97.9 174.2 108.0 98.2 195.9 112.9 133.5 114.0 70.9 400.9 117.3 155.9 375.6 243.7 326.6 69.3 131.2 172.2 140.8 277.8 62.0 161.3 327.1 161.5 71.4 78.5 149.1 173.6 182.4 78.0 576.9 277.6 63.4 119.0 201.4 137.1 162.9 347.8 164.7 185.1 199.3 34.7 369.4 199.4 130.7 26.2 46.1 232.1 153.1 214.8 100.2 138.8 253.8 290.7 58.3 125.9 197.2 106.9 278.0 83.3 101.7 128.5 126.6 513.6 102.6 278.1 154.1 185.1 APBB1 "Fe65, RIR" ENSG00000166313 "Amyloid beta precursor protein binding family B member 1" O00213 11 6395124-6419414 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, Transcription, Transcription regulation" "Activator, Chromatin regulator, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 152.9" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 102.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 85.6" "Lineage enriched" "Detected in all" 5 "T-cells: 85.6" "Cell line enhanced" "Detected in many" "SCLC-21H: 68.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038521, HPA038522" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA038521: AB_2676058, HPA038522: AB_2676059" "unprognostic (4.76e-2)" "unprognostic (1.98e-1)" "unprognostic (4.46e-3)" "unprognostic (1.97e-2)" "unprognostic (6.84e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (7.30e-2)" "unprognostic (3.22e-3)" "unprognostic (2.36e-1)" "prognostic favorable (1.86e-5)" "unprognostic (2.21e-1)" "prognostic favorable (7.44e-13)" "unprognostic (1.32e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (1.09e-2)" 18.1 23.8 101.7 11.9 119.4 2.7 18.0 116.6 121.1 39.5 65.1 43.3 7.0 43.5 4.3 14.9 38.3 11.4 42.0 123.3 105.3 21.5 3.8 22.5 13.9 123.9 106.0 39.2 16.3 21.4 61.3 8.6 135.0 23.7 4.7 23.3 13.4 25.9 42.3 12.2 19.2 33.2 109.4 13.8 19.4 12.7 112.1 28.9 19.1 54.0 11.1 31.2 23.5 152.9 0.0 14.9 50.6 22.8 26.7 27.4 0.2 24.6 41.7 41.2 51.4 26.4 10.3 0.0 3.6 44.3 36.9 0.5 44.4 7.5 19.4 27.8 33.7 0.3 9.3 0.9 19.3 0.2 9.9 24.8 1.9 19.4 2.9 35.3 51.7 1.2 1.1 0.7 15.3 0.5 0.5 0.1 18.3 0.8 15.5 0.2 2.0 0.2 1.7 0.2 68.1 37.6 3.6 3.0 15.9 15.2 2.1 3.4 22.8 4.2 24.8 27.5 5.0 13.8 6.8 2.0 21.1 0.0 14.3 8.4 1.7 0.3 23.2 1.5 25.2 6.7 32.5 30.2 1.7 16.2 85.6 51.7 1.6 16.5 0.6 0.3 48.7 29.9 101.7 119.4 116.6 121.1 123.3 105.3 123.9 106.0 135.0 109.4 112.1 152.9 9.6 19.2 5.4 22.9 7.5 5.0 12.1 3.6 12.0 45.8 6.6 5.7 50.5 11.5 5.4 5.5 22.9 0.4 4.6 1.1 25.4 18.2 5.6 7.6 9.5 13.9 19.3 4.0 47.1 4.2 0.7 15.2 4.6 2.3 1.3 10.8 15.7 3.3 1.2 40.4 44.8 1.2 0.0 1.9 4.0 13.1 9.6 1.8 8.8 7.5 3.2 24.7 9.2 49.3 102.3 8.0 1.7 19.2 1.4 8.3 0.4 21.6 17.3 20.1 6.6 10.0 17.3 6.9 13.7 3.2 2.8 0.8 20.1 7.0 1.3 5.4 APMAP "BSCv, C20orf3" ENSG00000101474 "Adipocyte plasma membrane associated protein" Q9HDC9 20 24962925-24992751 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 314.0" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 325.4;Hepatocytes: 251.1;Syncytiotrophoblasts: 751.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "granulocytes: 680.7;NK-cells: 343.8;T-cells: 367.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012863, HPA064700" Approved Approved "Plasma membrane" NA NA 130000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA012863: AB_1845683, HPA064700: AB_2685328" "unprognostic (4.07e-3)" "unprognostic (2.50e-2)" "unprognostic (1.20e-1)" "unprognostic (8.16e-2)" "unprognostic (6.79e-2)" "unprognostic (2.14e-2)" "unprognostic (1.10e-2)" "unprognostic (4.09e-2)" "unprognostic (3.10e-2)" "unprognostic (1.19e-2)" "unprognostic (6.46e-2)" "unprognostic (1.54e-1)" "unprognostic (7.99e-3)" "unprognostic (8.26e-2)" "unprognostic (1.67e-1)" "unprognostic (1.23e-1)" "unprognostic (3.51e-2)" 168.0 44.6 59.2 47.2 60.1 187.4 84.6 76.0 65.4 41.8 62.2 46.5 32.7 46.8 106.3 26.7 46.0 43.1 37.5 64.1 72.6 50.5 314.0 53.2 44.0 61.4 62.8 40.8 45.2 83.4 78.7 80.2 68.6 44.2 42.9 32.0 40.1 47.9 39.5 55.8 34.7 49.2 60.5 66.6 38.5 54.2 69.7 42.4 209.1 24.4 34.1 51.8 29.5 68.8 110.6 191.3 90.0 139.5 175.3 97.5 94.4 141.8 153.4 133.3 137.4 113.7 189.3 45.9 161.1 170.6 232.1 198.1 85.0 165.1 149.1 62.3 69.7 51.2 66.0 226.9 140.9 99.5 115.4 134.3 226.9 154.9 107.0 173.8 192.5 73.4 61.5 195.8 128.6 168.1 68.9 108.2 59.3 166.6 172.1 56.3 312.8 96.3 140.2 98.9 150.6 59.4 146.9 240.5 157.1 92.0 87.6 78.8 173.7 156.9 140.6 134.7 209.5 113.0 134.3 50.9 83.1 148.0 151.9 61.8 99.3 198.9 367.9 98.6 228.8 36.4 100.8 268.2 102.1 37.4 78.6 202.2 680.7 343.8 71.3 50.7 75.0 363.3 59.2 60.1 76.0 65.4 64.1 72.6 61.4 62.8 68.6 60.5 69.7 68.8 28.5 19.2 32.7 25.8 22.2 24.3 46.7 77.6 17.1 51.4 48.1 32.1 17.5 34.3 39.7 49.7 10.4 325.4 163.2 18.9 17.6 72.0 22.9 18.0 26.3 42.4 18.0 33.6 24.0 45.4 50.6 40.6 15.3 23.8 36.1 68.6 41.4 251.1 95.9 16.8 25.4 19.4 85.5 50.0 94.8 32.5 65.0 59.5 46.2 42.2 105.1 35.0 222.5 19.6 15.9 40.8 25.4 82.0 54.9 34.1 20.8 13.2 24.5 22.5 39.5 36.9 33.2 97.1 90.1 16.7 20.0 751.1 96.7 38.3 28.0 28.1 APOD ENSG00000189058 "Apolipoprotein D" P05090 3 195568705-195584033 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 5037.8" "Cell type enhanced" "Detected in many" "Fibroblasts: 4485.3;Leydig cells: 2077.4;Melanocytes: 1028.1;Peritubular cells: 994.5" "Cancer enriched" "Detected in all" 4 "melanoma: 925.2" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "memory B-cell: 5.0" "Lineage enriched" "Detected in single" 14 "B-cells: 5.0" "Group enriched" "Detected in many" 6 "ASC diff: 3507.4;ASC TERT1: 1918.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040520 Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 98900000000 90000000000 "Cluster 37: B-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA040520: AB_2677020" "prognostic favorable (5.51e-4)" "unprognostic (7.62e-3)" "unprognostic (7.85e-3)" "unprognostic (3.34e-3)" "unprognostic (2.20e-1)" "unprognostic (1.02e-2)" "unprognostic (3.09e-2)" "unprognostic (2.06e-3)" "unprognostic (1.26e-1)" "unprognostic (3.45e-1)" "unprognostic (3.38e-1)" "unprognostic (3.19e-1)" "unprognostic (6.90e-3)" "prognostic unfavorable (6.02e-4)" "unprognostic (1.38e-1)" "prognostic unfavorable (4.12e-4)" "unprognostic (1.71e-3)" 2071.8 84.8 949.6 13.9 1157.3 0.9 5037.8 1174.9 1364.1 620.2 1370.1 144.7 56.0 496.7 155.7 160.0 750.6 213.3 1007.8 952.8 1010.4 49.7 7.1 183.5 24.6 1148.3 1040.5 131.2 212.4 61.9 192.2 350.5 1122.0 419.8 57.2 0.8 1272.3 183.8 1154.9 970.1 88.4 96.2 1027.5 8.2 402.6 75.7 1070.2 113.5 828.8 625.3 20.8 434.4 591.7 1347.6 0.0 2.2 0.5 0.7 3507.4 1918.1 6.1 31.3 7.6 0.1 0.2 222.4 0.4 0.4 0.9 1.8 0.0 0.9 0.4 10.5 0.3 0.3 2.4 0.3 0.2 0.1 12.5 0.3 0.5 91.4 21.0 0.2 17.0 0.3 4.3 0.2 0.2 0.9 5.3 1.3 0.1 0.7 0.5 38.9 0.5 0.1 0.0 0.6 0.0 2.8 0.7 0.5 0.0 34.8 31.8 1.3 67.2 0.1 0.4 0.5 1.4 0.4 0.1 0.2 0.3 9.2 1.0 0.4 420.3 0.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 949.6 1157.3 1174.9 1364.1 952.8 1010.4 1148.3 1040.5 1122.0 1027.5 1070.2 1347.6 543.2 0.0 11.0 2.9 7.5 145.0 16.0 25.4 46.7 0.0 121.6 138.7 26.9 1.5 81.8 5.5 0.0 5.4 15.9 1.4 0.0 0.4 9.7 16.3 393.7 114.1 46.3 0.0 3.3 0.0 4.2 4485.3 7.7 7.0 0.0 0.0 21.4 0.0 13.3 0.0 2.1 0.7 10.2 0.3 193.2 51.0 2077.4 31.8 1028.1 279.2 1.0 0.0 0.0 300.6 221.5 2.3 0.3 994.5 19.2 25.7 0.0 0.2 128.9 0.0 19.7 100.3 210.7 10.5 4.0 24.1 102.6 5.9 23.5 7.0 0.6 47.3 AQP1 "CHIP28, CO" ENSG00000240583 "Aquaporin 1 (Colton blood group)" P29972 7 30911853-30925517 "Blood group antigen proteins, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 727.9;Alveolar cells type 2: 231.8;Cholangiocytes: 358.9;Endothelial cells: 606.7;Hepatic stellate cells: 325.6;Proximal tubular cells: 319.7" "Cancer enhanced" "Detected in all" "glioma: 336.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 34.7;HeLa: 12.5;SH-SY5Y: 14.7;U-2 OS: 14.9;WM-115: 76.4" "Group enriched" "Detected in some" 6 "medulla oblongata: 5.5;spinal cord: 22.0" "CAB001707, HPA019206" Enhanced Supported "Plasma membrane" NA NA 49000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB001707: , HPA019206: AB_1844965" "unprognostic (4.18e-2)" "unprognostic (7.82e-3)" "unprognostic (1.10e-2)" "unprognostic (1.08e-1)" "unprognostic (1.02e-1)" "prognostic favorable (6.52e-4)" "unprognostic (1.95e-3)" "unprognostic (1.66e-1)" "unprognostic (3.00e-2)" "unprognostic (3.80e-2)" "unprognostic (4.16e-1)" "unprognostic (2.05e-2)" "prognostic favorable (1.32e-8)" "unprognostic (3.43e-2)" "unprognostic (1.61e-1)" "unprognostic (2.09e-1)" "unprognostic (7.21e-2)" 385.9 30.5 86.5 29.3 149.4 50.7 250.3 106.2 79.1 148.9 277.7 97.7 51.0 160.8 41.7 143.5 165.8 162.3 206.8 141.0 124.4 522.9 12.9 413.9 45.5 512.3 181.1 28.1 257.6 48.2 15.2 36.9 199.5 83.8 32.6 0.7 114.0 84.4 199.0 112.6 90.8 142.4 357.3 12.6 80.4 7.8 138.8 39.0 113.2 388.6 34.2 138.5 143.2 432.4 0.1 0.5 0.3 0.6 0.3 1.3 0.7 2.4 0.5 0.0 0.0 0.2 0.8 0.1 34.7 1.9 0.1 0.4 0.0 0.0 0.0 0.3 0.3 0.5 12.5 0.0 0.3 0.3 0.1 4.9 0.1 0.3 0.0 0.1 5.1 0.1 2.3 0.1 0.0 0.0 0.0 0.9 0.7 1.0 0.0 0.0 8.9 0.3 0.9 0.0 0.3 14.7 1.9 1.2 0.0 4.6 0.3 0.1 0.0 0.0 14.9 1.1 0.5 0.8 0.6 0.6 0.0 0.1 76.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 86.5 149.4 106.2 79.1 141.0 124.4 512.3 181.1 199.5 357.3 138.8 432.4 727.9 179.5 231.8 75.7 3.6 91.5 1.2 0.3 5.2 0.7 11.5 29.0 78.0 358.9 3.9 31.3 8.4 3.4 3.7 3.7 29.4 53.3 2.3 2.5 1.2 606.7 7.3 86.9 3.5 2.5 4.8 67.6 0.0 0.9 1.3 0.5 325.6 2.0 3.7 0.0 1.0 28.6 0.0 5.1 107.7 2.1 1.2 6.0 88.9 0.0 1.6 0.4 0.0 0.5 0.2 2.4 14.5 3.4 3.7 1.2 90.6 319.7 6.2 0.4 13.1 23.1 42.3 0.3 1.5 2.6 78.7 7.3 8.1 4.7 67.8 1.0 AQP3 GIL ENSG00000165272 "Aquaporin 3 (Gill blood group)" Q92482 9 33441156-33447596 "Blood group antigen proteins, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 1526.1;skin 1: 581.9;urinary bladder: 688.6" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 1923.3;Basal prostatic cells: 982.0;Collecting duct cells: 1609.3;Prostatic glandular cells: 1430.8;Squamous epithelial cells: 2189.3;Suprabasal keratinocytes: 2485.4;Urothelial cells: 2455.4" "Group enriched" "Detected in all" 5 "cervical cancer: 319.0;head and neck cancer: 283.7;lung cancer: 146.8;urothelial cancer: 221.3" "Group enriched" "Detected in many" 4 "hippocampal formation: 5.3;medulla oblongata: 16.0;pons: 21.0" "Immune cell enhanced" "Detected in many" "MAIT T-cell: 181.7;T-reg: 205.4" "Lineage enriched" "Detected in many" 18 "T-cells: 205.4" "Cell line enhanced" "Detected in many" "HaCaT: 127.1;HeLa: 213.2;JURKAT: 130.7;RT4: 216.6;SK-BR-3: 149.7;U-266/70: 151.2;U-266/84: 213.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014924 Enhanced Supported "Plasma membrane" NA NA "Cluster 13: T-cells - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA014924: AB_2669120" "unprognostic (4.29e-2)" "prognostic favorable (5.31e-4)" "unprognostic (1.15e-1)" "unprognostic (3.26e-2)" "unprognostic (1.84e-2)" "unprognostic (1.11e-2)" "unprognostic (9.95e-2)" "unprognostic (1.64e-1)" "unprognostic (3.46e-1)" "unprognostic (9.06e-2)" "unprognostic (4.87e-2)" "unprognostic (1.25e-1)" "unprognostic (1.54e-2)" "unprognostic (1.16e-2)" "unprognostic (2.59e-1)" "unprognostic (3.73e-2)" "unprognostic (4.51e-2)" 10.9 2.1 1.5 16.8 0.4 19.7 36.6 2.4 3.4 173.3 1.4 10.3 73.4 10.9 2.9 1526.1 25.4 9.4 31.5 5.3 0.4 131.7 118.6 114.0 16.1 16.0 1.6 12.1 43.1 2.0 2.8 6.0 21.0 85.6 10.1 1.7 399.7 36.8 5.3 581.9 100.5 3.2 0.2 110.1 35.9 2.8 0.8 233.9 2.3 26.7 172.5 688.6 529.9 0.9 0.6 38.6 1.9 0.0 67.7 12.2 1.0 0.3 0.9 0.9 1.1 20.5 12.0 0.5 9.1 0.0 0.5 127.1 6.2 0.7 0.2 61.6 6.0 4.3 213.2 1.9 0.4 1.3 1.3 1.9 6.5 0.5 0.2 0.2 0.5 130.7 67.4 58.8 6.9 29.1 60.4 23.0 5.3 88.6 0.7 0.9 94.3 10.8 1.3 216.6 1.7 4.7 32.3 149.7 0.1 8.0 0.9 10.6 1.2 0.0 1.0 0.4 0.4 151.2 213.6 14.5 0.5 0.4 0.2 1.6 0.5 0.1 20.2 0.4 181.7 11.3 171.9 52.8 0.3 3.0 97.3 47.1 2.3 3.0 0.5 11.1 205.4 43.0 1.5 0.4 2.4 3.4 5.3 0.4 16.0 1.6 21.0 0.2 0.8 0.9 9.2 38.5 249.9 0.0 42.4 1923.3 982.0 381.4 811.0 9.7 56.8 27.8 3.4 157.3 436.3 1609.3 2.1 0.9 21.6 2.7 0.0 37.4 2.2 82.3 21.4 37.1 8.3 71.4 0.3 48.9 2.0 27.5 16.3 96.2 20.8 0.2 16.4 137.3 2.2 0.0 0.1 104.0 315.3 3.5 122.9 0.6 33.2 15.3 158.3 0.0 1.6 0.4 4.1 0.5 0.2 28.5 8.1 1.2 246.9 1430.8 343.1 31.9 546.0 0.5 0.0 10.2 35.8 0.7 1.9 2189.3 2485.4 50.2 73.4 1.6 7.3 2455.4 AQP5 ENSG00000161798 "Aquaporin 5" P55064 12 49961872-49965682 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 622.6;testis: 222.0" "Group enriched" "Detected in many" 7 "Early spermatids: 1542.9;Late spermatids: 4265.6" "Cancer enhanced" "Detected in many" "endometrial cancer: 87.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 22 "OE19: 223.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA065008 Enhanced Approved "Plasma membrane" NA NA "Cluster 24: Salivary gland - Salivary secretion" "Cluster 21: OE19 - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA065008: AB_2685401" "unprognostic (4.67e-3)" "unprognostic (5.00e-2)" "unprognostic (3.30e-1)" "unprognostic (6.00e-3)" "unprognostic (1.92e-3)" "prognostic favorable (1.75e-5)" "unprognostic (4.13e-3)" "unprognostic (1.02e-2)" "unprognostic (9.39e-2)" "unprognostic (3.70e-3)" "unprognostic (2.88e-3)" "unprognostic (2.46e-3)" "unprognostic (1.69e-4)" "unprognostic (2.53e-1)" "unprognostic (5.28e-2)" "unprognostic (2.51e-3)" "unprognostic (9.11e-3)" 2.9 0.8 2.7 0.1 3.7 0.2 17.1 3.3 2.7 12.9 1.5 0.4 15.3 2.7 0.2 16.5 0.7 2.8 4.0 2.4 2.9 1.9 0.1 7.6 0.0 3.3 3.9 0.2 2.0 3.0 1.2 0.0 3.1 1.3 0.0 1.0 622.6 1.0 0.2 112.7 0.1 0.3 2.6 0.4 52.3 222.0 3.8 0.0 1.6 0.0 0.1 0.3 0.4 2.6 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 8.7 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.7 223.2 0.0 10.1 0.0 0.0 0.3 0.0 0.2 0.1 0.8 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 3.7 3.3 2.7 2.4 2.9 3.3 3.9 3.1 2.6 3.8 2.6 0.5 57.7 3.1 0.0 0.1 1.3 0.5 18.3 0.0 0.8 53.9 48.0 0.3 0.0 56.4 7.3 0.0 0.0 0.1 0.0 0.0 0.1 1542.9 1.5 0.1 1.8 0.0 0.0 0.0 0.2 0.0 1.4 34.7 2.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 26.4 0.0 1.6 4265.6 28.6 1.7 295.3 0.0 0.0 53.7 0.0 3.0 0.1 7.2 0.0 19.2 0.3 1.6 0.0 0.0 9.7 1.7 19.7 0.0 1.8 403.9 15.9 1.3 0.9 0.0 0.6 18.7 0.0 0.6 ARHGAP19 "FLJ00194, MGC14258" ENSG00000213390 "Rho GTPase activating protein 19" Q14CB8 10 97222173-97292673 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 21.3" "Cell type enhanced" "Detected in many" "Spermatocytes: 13.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA035777, HPA043231" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane" "HPA035777: AB_2674777, HPA043231: AB_10796791" "unprognostic (5.88e-2)" "unprognostic (2.39e-2)" "unprognostic (2.47e-2)" "unprognostic (1.91e-2)" "unprognostic (1.68e-1)" "unprognostic (8.79e-3)" "unprognostic (1.60e-3)" "unprognostic (2.00e-2)" "unprognostic (9.89e-2)" "unprognostic (1.97e-2)" "unprognostic (6.76e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (7.47e-5)" "unprognostic (1.12e-2)" "unprognostic (1.56e-1)" "unprognostic (2.23e-2)" "unprognostic (4.29e-2)" 3.2 2.1 2.4 7.1 3.9 18.8 7.6 2.9 2.0 3.7 0.6 4.3 3.6 5.5 2.6 4.0 4.7 3.4 3.3 1.6 3.2 3.9 2.4 4.7 13.3 4.3 3.2 9.3 1.6 5.5 0.5 5.3 4.4 3.6 4.5 3.2 3.2 3.0 1.8 3.6 5.3 4.5 3.3 7.9 3.6 18.5 2.9 21.3 3.2 4.2 13.2 2.9 2.0 5.9 18.5 6.0 31.9 56.0 2.1 8.3 9.8 9.0 9.1 13.9 9.9 11.2 16.1 40.9 7.4 6.2 8.3 12.3 27.1 11.2 17.8 20.4 14.7 27.0 7.8 7.8 2.1 42.1 27.8 4.2 3.9 9.8 22.3 4.7 19.6 57.3 27.1 21.0 12.1 8.9 39.3 9.1 16.9 12.2 5.5 45.5 27.1 11.4 4.2 7.8 2.5 14.5 6.7 3.1 14.5 11.9 19.4 22.2 9.1 5.7 6.8 8.9 23.6 18.6 20.7 54.3 7.0 48.7 6.4 21.5 7.2 11.1 5.0 6.8 4.7 5.5 4.9 4.7 5.4 5.3 5.6 5.0 15.8 4.4 6.1 3.0 6.3 5.5 2.4 3.9 2.9 2.0 1.6 3.2 4.3 3.2 4.4 3.3 2.9 5.9 5.8 3.2 3.2 0.0 4.1 0.9 1.4 2.8 3.4 2.8 3.6 8.8 1.9 2.8 1.6 0.0 0.0 2.0 3.6 2.2 0.0 1.3 9.1 2.4 2.6 5.4 0.0 6.7 0.0 1.6 3.5 3.9 1.5 3.6 5.1 5.6 11.7 2.6 3.5 6.7 0.0 1.9 2.0 9.3 1.9 6.3 3.4 6.1 1.8 0.0 5.4 1.7 5.2 0.0 0.0 1.4 2.9 4.1 5.8 2.6 2.6 0.7 4.8 1.3 0.0 3.1 2.2 13.7 10.4 5.3 2.4 1.0 3.5 3.4 3.5 1.6 ARHGEF15 "ARGEF15, FLJ13791, KIAA0915, MGC44868, Vsm-RhoGEF" ENSG00000198844 "Rho guanine nucleotide exchange factor 15" O94989 17 8310241-8322514 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 47.7;breast: 41.6" "Group enriched" "Detected in some" 4 "Adipocytes: 66.4;Endothelial cells: 48.9;Hepatic stellate cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 48 "HUVEC TERT2: 40.4;TIME: 49.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA044443, HPA063495" Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA044443: AB_10960424, HPA063495: AB_2685023" "unprognostic (3.02e-1)" "unprognostic (2.97e-1)" "unprognostic (1.18e-2)" "unprognostic (7.09e-3)" "unprognostic (3.82e-1)" "unprognostic (7.29e-4)" "unprognostic (1.43e-2)" "unprognostic (1.84e-1)" "unprognostic (1.42e-1)" "unprognostic (3.40e-1)" "unprognostic (1.06e-2)" "unprognostic (1.45e-1)" "unprognostic (2.23e-3)" "unprognostic (4.88e-2)" "unprognostic (1.33e-1)" "unprognostic (1.89e-1)" "unprognostic (9.56e-3)" 47.7 5.9 4.6 4.1 4.2 0.0 41.6 4.1 4.7 8.7 3.0 6.9 3.1 10.9 1.6 4.8 9.8 7.3 35.5 4.1 4.1 15.8 2.9 22.1 3.1 4.7 4.5 3.8 4.2 3.4 4.0 14.7 4.8 8.0 2.0 0.2 5.1 3.5 13.2 7.7 6.5 7.2 4.0 7.9 6.9 2.2 5.2 1.6 12.4 10.9 1.8 12.3 8.3 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 49.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 4.2 4.1 4.7 4.1 4.1 4.7 4.5 4.8 4.0 5.2 3.6 66.4 0.0 3.0 0.3 0.5 2.8 0.3 0.0 0.6 0.8 0.5 0.4 8.9 2.8 0.0 1.8 0.0 0.0 0.2 0.1 0.0 0.0 3.3 0.4 0.2 48.9 0.0 0.0 0.2 0.0 0.1 1.0 0.0 1.3 0.0 0.0 37.1 0.0 0.1 0.0 0.5 0.0 0.0 1.4 2.8 4.4 0.0 0.5 7.2 11.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.4 0.0 0.0 0.0 0.1 0.0 1.6 1.5 0.4 0.2 0.2 1.0 0.1 0.3 0.7 0.0 0.3 ARMH4 "C14orf37, UT2" ENSG00000139971 "Armadillo like helical domain containing 4" Q86TY3 14 57999735-58298139 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 12.8;kidney: 8.3" "Cell type enhanced" "Detected in some" "Adipocytes: 15.8;Collecting duct cells: 12.9;Endometrial ciliated cells: 10.2;Endometrial stromal cells: 7.7;Granulosa cells: 26.0;Theca cells: 44.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 9.7;AN3-CA: 6.1;fHDF/TERT166: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001580, HPA001789" Enhanced Approved "Plasma membrane" NA NA 1800000 "Cluster 21: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA001580: AB_2666366, HPA001789: AB_1078328" "unprognostic (2.56e-2)" "unprognostic (2.04e-2)" "unprognostic (1.20e-3)" "unprognostic (8.56e-2)" "unprognostic (1.15e-1)" "unprognostic (6.97e-3)" "unprognostic (1.94e-1)" "unprognostic (7.84e-3)" "unprognostic (2.66e-1)" "unprognostic (2.32e-1)" "unprognostic (2.42e-1)" "unprognostic (1.01e-1)" "unprognostic (3.87e-8)" "unprognostic (5.22e-6)" "unprognostic (4.93e-2)" "unprognostic (8.74e-4)" "unprognostic (3.01e-4)" 1.2 2.5 2.3 0.6 3.6 0.7 0.8 8.5 3.5 1.8 0.0 0.7 0.5 3.0 1.8 0.8 2.1 1.8 3.1 2.6 2.1 8.3 0.8 0.7 0.4 11.5 5.1 4.3 1.0 3.6 1.3 0.4 12.8 1.6 1.0 1.2 0.7 1.4 0.2 1.0 0.7 2.3 1.0 0.5 1.4 2.2 1.6 0.2 1.5 1.9 0.3 1.2 0.9 0.7 0.0 0.0 9.7 6.1 4.7 1.7 0.0 1.9 1.5 0.3 0.3 0.5 0.1 0.0 0.6 10.8 1.2 0.0 2.9 0.0 0.4 0.1 1.0 0.0 0.0 0.5 0.2 0.0 4.8 1.8 0.0 0.2 0.2 2.7 0.5 0.8 0.1 0.3 1.2 0.3 0.0 0.0 4.5 0.0 2.0 1.4 0.3 2.5 3.9 0.3 1.1 0.0 0.1 0.0 0.3 2.7 0.2 0.2 0.1 1.3 3.5 0.5 2.6 0.3 0.2 0.0 3.0 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 3.6 8.5 3.5 2.6 2.1 11.5 5.1 12.8 1.0 1.6 0.7 15.8 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.0 0.0 0.0 12.9 0.0 0.2 0.7 0.0 0.0 2.1 0.0 10.2 7.7 2.3 0.0 0.0 0.0 1.3 0.4 3.0 0.0 2.4 0.0 26.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 2.6 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.3 0.3 44.5 0.0 0.0 ASB5 ENSG00000164122 "Ankyrin repeat and SOCS box containing 5" Q8WWX0 4 176213673-176277571 "Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "skeletal muscle: 217.2;tongue: 67.0" "Cell type enhanced" "Detected in some" "Early spermatids: 52.7;Late spermatids: 293.6;Skeletal myocytes: 79.6" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.5;prostate cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 16 "LHCN-M2: 1184.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA028870 Approved "Plasma membrane" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028870: AB_10611679" "unprognostic (1.76e-1)" "prognostic unfavorable (5.67e-4)" "unprognostic (1.90e-1)" "unprognostic (7.38e-2)" "unprognostic (1.32e-1)" "unprognostic (1.06e-2)" "unprognostic (4.28e-2)" "unprognostic (1.65e-1)" "unprognostic (6.80e-3)" 0.1 0.0 0.4 0.9 0.5 0.0 0.0 1.3 1.0 1.0 0.2 11.1 0.3 0.6 0.1 10.5 0.1 1.2 3.9 0.5 0.4 0.7 0.0 0.2 0.0 0.9 1.5 0.0 0.0 0.1 0.4 0.0 0.8 12.9 3.3 0.0 23.9 0.3 217.2 0.2 1.2 2.5 0.8 0.0 4.7 7.3 0.5 0.1 0.0 67.0 0.0 19.2 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 29.1 0.0 25.9 54.7 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 61.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1184.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 74.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 1.3 1.0 0.5 0.4 0.9 1.5 0.8 0.8 0.5 1.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.7 0.0 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 293.6 1.2 0.3 0.0 0.0 0.0 0.0 0.0 11.6 0.8 0.0 0.0 1.2 0.0 0.1 0.0 0.3 0.0 0.0 0.0 79.6 0.6 0.9 1.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 ATP1B3 "CD298, FLJ29027" ENSG00000069849 "ATPase Na+/K+ transporting subunit beta 3" P54709 3 141876124-141926549 "CD markers, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 982.6;Late spermatids: 930.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020697, HPA048963" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB020697: , HPA048963: AB_2680574" "unprognostic (2.31e-1)" "unprognostic (1.11e-3)" "unprognostic (2.75e-1)" "prognostic favorable (5.19e-5)" "unprognostic (2.60e-2)" "unprognostic (3.31e-2)" "prognostic unfavorable (6.32e-6)" "unprognostic (8.11e-3)" "unprognostic (6.99e-2)" "unprognostic (5.37e-3)" "unprognostic (1.48e-2)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.29e-5)" "unprognostic (5.14e-2)" "unprognostic (2.04e-1)" "unprognostic (7.19e-3)" "unprognostic (6.15e-2)" 229.4 349.6 62.2 81.0 62.8 63.0 87.0 78.5 78.8 98.4 100.5 146.7 112.7 75.7 37.6 182.3 96.2 55.4 102.8 63.6 74.7 128.4 24.5 191.0 41.3 71.1 66.6 180.0 36.7 20.3 168.7 96.7 76.5 102.0 168.0 43.6 85.8 46.2 26.7 259.3 125.0 71.4 68.7 65.7 66.3 75.8 70.6 51.4 75.8 16.0 57.1 101.0 161.2 62.2 280.8 170.1 155.5 145.6 411.7 118.0 354.7 322.2 287.6 224.2 252.1 253.7 136.5 223.3 278.2 243.5 328.4 595.8 157.0 152.2 253.4 120.4 190.0 195.7 161.4 156.8 161.7 164.9 149.1 126.5 355.1 179.1 169.7 162.4 245.7 156.3 135.9 193.7 233.8 114.6 165.6 275.0 213.6 384.5 76.1 225.0 116.4 227.1 191.1 186.7 127.6 86.0 413.2 188.5 455.9 270.7 145.6 197.2 170.7 196.4 76.3 298.8 189.8 138.0 197.6 367.5 259.5 176.5 165.2 69.7 104.1 35.4 70.4 174.3 51.7 39.7 56.3 74.8 103.3 30.4 32.6 59.6 6.7 32.0 260.4 64.8 68.4 103.7 62.2 62.8 78.5 78.8 63.6 74.7 71.1 66.6 76.5 68.7 70.6 62.2 114.7 57.7 41.9 38.2 143.4 492.8 428.3 535.9 326.7 35.9 53.0 46.4 19.7 17.2 177.6 220.7 25.0 281.3 464.5 982.6 41.1 73.9 465.9 86.0 72.2 199.2 56.1 147.1 107.5 60.6 226.8 164.1 24.5 127.2 130.7 94.3 100.6 9.0 305.9 25.2 91.2 65.2 164.8 148.0 678.3 930.5 84.8 455.3 222.3 37.5 364.8 46.3 75.2 46.3 54.7 70.6 321.1 68.4 153.1 396.5 413.3 41.5 33.3 28.4 124.9 99.5 265.2 69.0 200.2 178.4 414.4 391.4 216.1 122.2 134.9 370.2 ATP2B1 PMCA1 ENSG00000070961 "ATPase plasma membrane Ca2+ transporting 1" P20020 12 89588049-89709300 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 106.8" "Cell type enhanced" "Detected in all" "Excitatory neurons: 781.6;Langerhans cells: 435.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTERT-HME1: 314.6;LHCN-M2: 501.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005605, HPA011166, HPA012945" Enhanced Supported Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB005605: AB_2061563, HPA011166: AB_1855484, HPA012945: AB_1855483" "unprognostic (6.78e-2)" "unprognostic (5.27e-2)" "unprognostic (1.57e-2)" "unprognostic (8.23e-2)" "unprognostic (1.72e-1)" "unprognostic (6.44e-2)" "prognostic unfavorable (7.74e-4)" "unprognostic (2.77e-2)" "unprognostic (2.46e-2)" "unprognostic (7.82e-2)" "unprognostic (5.98e-2)" "unprognostic (2.68e-1)" "unprognostic (4.60e-2)" "unprognostic (1.92e-2)" "unprognostic (2.31e-1)" "unprognostic (1.01e-1)" "unprognostic (1.13e-2)" 18.5 11.2 33.0 25.6 92.0 106.8 19.6 14.0 59.1 18.8 0.0 33.1 40.8 18.2 12.1 14.7 18.6 25.2 11.0 52.7 4.9 16.4 22.7 21.3 29.2 0.0 14.4 13.1 17.1 21.5 11.0 27.3 0.0 13.9 32.3 71.2 11.5 14.9 24.4 26.0 30.1 19.7 0.0 30.7 29.0 23.0 10.9 18.4 14.4 24.1 28.8 37.0 10.6 34.9 24.0 117.8 45.5 22.1 64.5 102.2 20.9 71.2 232.6 67.5 106.8 47.7 21.6 46.8 4.9 99.3 77.6 21.0 40.3 19.7 187.5 16.2 46.9 16.6 39.8 41.9 209.6 70.7 26.6 85.0 36.9 210.8 314.6 78.9 17.5 17.6 27.9 16.6 501.1 37.6 22.1 30.1 35.6 32.9 55.6 31.1 146.4 19.7 64.4 108.5 42.9 23.4 82.6 22.9 20.2 91.7 33.9 7.8 12.5 181.8 29.4 67.6 78.9 12.7 21.2 49.1 82.6 19.6 41.0 9.4 39.4 22.3 20.9 42.5 26.4 84.5 36.3 26.8 51.3 84.4 13.2 16.8 127.1 27.0 86.1 9.0 53.7 21.8 33.0 92.0 14.0 59.1 52.7 4.9 0.0 14.4 0.0 0.0 10.9 34.9 46.0 44.8 46.0 90.8 226.4 201.6 71.0 29.3 76.2 370.9 30.9 109.7 20.3 45.8 30.0 53.3 154.3 176.8 139.8 181.5 1.9 27.6 2.3 29.3 61.0 63.6 91.6 31.5 781.6 28.5 42.1 91.6 44.9 59.4 31.6 45.5 49.6 39.5 193.5 302.9 279.1 30.7 16.2 116.0 435.1 9.6 29.2 285.4 55.2 126.5 157.1 96.4 50.4 193.5 91.9 25.5 80.6 32.0 133.9 54.7 75.0 22.1 20.6 113.3 32.9 97.0 69.5 44.5 130.7 30.4 204.7 228.8 125.1 76.0 65.9 90.2 ATP2B4 "ATP2B2, MXRA1, PMCA4" ENSG00000058668 "ATPase plasma membrane Ca2+ transporting 4" P23634 1 203626787-203744081 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calmodulin-binding, Translocase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "smooth muscle: 175.3" "Cell type enhanced" "Detected in many" "Adipocytes: 171.6;Oligodendrocyte precursor cells: 199.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BJ: 200.0;BJ hTERT+: 276.4;fHDF/TERT166: 212.8;SuSa: 222.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016118, HPA040431" Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB016118: AB_2061729, HPA040431: AB_2676980" "unprognostic (7.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.60e-2)" "unprognostic (8.17e-2)" "unprognostic (2.53e-2)" "unprognostic (9.23e-3)" "unprognostic (8.68e-2)" "unprognostic (3.81e-2)" "unprognostic (9.74e-2)" "unprognostic (1.70e-1)" "unprognostic (1.64e-2)" "unprognostic (1.12e-1)" "prognostic unfavorable (1.21e-4)" "unprognostic (3.52e-3)" "unprognostic (2.61e-2)" "unprognostic (1.30e-1)" "unprognostic (2.56e-3)" 58.9 25.0 39.7 25.6 36.3 16.0 16.6 0.0 33.5 47.5 0.3 58.2 12.5 104.5 20.1 32.5 48.4 25.2 59.5 40.2 13.3 9.9 9.3 35.1 12.8 8.0 8.0 40.6 9.9 11.8 3.8 40.6 11.2 33.0 30.2 42.5 7.1 69.7 14.4 54.8 14.4 175.3 0.2 12.2 15.4 27.4 44.7 21.7 15.1 27.7 19.4 37.2 15.3 2.6 45.7 7.8 15.6 15.1 120.4 175.1 84.5 200.0 276.4 32.1 27.4 3.8 22.8 9.8 28.8 212.8 43.5 43.5 22.6 27.7 34.3 126.5 8.0 28.7 37.4 2.5 43.1 42.0 51.3 130.5 26.9 102.9 16.2 81.6 63.5 57.1 12.9 20.3 25.1 2.5 44.3 14.5 9.7 8.7 24.2 22.3 11.6 16.7 11.3 4.0 4.6 6.7 68.3 10.5 30.2 222.1 9.3 21.4 54.9 80.5 11.4 136.6 48.3 13.4 20.9 5.4 80.7 31.0 24.5 3.2 2.0 0.0 8.7 1.3 6.4 0.9 5.4 7.2 2.2 0.3 1.3 3.4 4.0 3.8 2.2 3.7 5.7 2.7 39.7 36.3 0.0 33.5 40.2 13.3 8.0 8.0 11.2 0.2 44.7 2.6 171.6 89.8 68.2 127.6 9.9 97.1 18.9 43.1 41.5 4.8 11.2 9.4 76.5 7.2 35.0 18.4 2.1 27.9 56.2 2.2 0.0 35.3 5.8 78.0 92.4 67.6 23.9 35.9 55.9 14.9 18.9 56.0 13.7 89.7 10.1 30.6 58.9 18.2 38.5 117.8 9.8 2.4 14.2 14.7 38.8 4.8 43.8 20.4 26.6 37.5 18.1 136.1 66.9 199.0 40.4 31.4 11.1 38.0 27.6 48.2 7.2 3.3 39.7 7.8 19.7 50.7 81.2 21.7 2.8 54.7 150.9 26.0 59.7 8.0 3.3 62.0 ATP4B ATP6B ENSG00000186009 "ATPase H+/K+ transporting subunit beta" P51164 13 113648804-113658198 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Hydrogen ion transport, Ion transport, Potassium transport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 305 "stomach 1: 1096.8" "Cell type enriched" "Detected in some" 76 "Gastric mucus-secreting cells: 145.8" "Cancer enriched" "Detected in some" 12 "stomach cancer: 8.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045400, HPA052649" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA045400: AB_2679314, HPA052649: AB_2681900" "unprognostic (9.92e-2)" "unprognostic (2.19e-1)" "unprognostic (2.66e-1)" "unprognostic (4.86e-1)" "unprognostic (6.43e-3)" "unprognostic (7.81e-3)" "unprognostic (1.95e-1)" "unprognostic (3.22e-1)" "unprognostic (6.50e-2)" "unprognostic (6.65e-4)" "unprognostic (2.25e-1)" "unprognostic (2.78e-1)" "unprognostic (3.78e-2)" 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 3.5 0.3 0.0 0.0 0.0 0.3 3.3 0.0 0.2 0.2 0.1 0.4 0.1 0.4 0.0 0.5 0.6 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 1096.8 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.5 0.6 0.2 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 145.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 B3GALT2 beta3Gal-T2 ENSG00000162630 "Beta-1,3-galactosyltransferase 2" O43825 1 193178730-193186613 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 17.2;gallbladder: 15.0;heart muscle: 21.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 46.6;Cardiomyocytes: 34.4;Excitatory neurons: 27.6;Inhibitory neurons: 28.3;Leydig cells: 31.7;Peritubular cells: 21.1" "Cancer enhanced" "Detected in some" "glioma: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "MAIT T-cell: 8.4" "Lineage enriched" "Detected in single" 53 "T-cells: 8.4" "Group enriched" "Detected in some" 4 "AF22: 18.3;ASC TERT1: 8.1;LHCN-M2: 12.6;WM-115: 21.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078659 Approved "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 17: WM-115 - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA078659: AB_2686887" "unprognostic (1.83e-2)" "unprognostic (3.81e-2)" "unprognostic (1.91e-2)" "unprognostic (1.17e-1)" "unprognostic (3.67e-1)" "unprognostic (1.58e-3)" "unprognostic (2.34e-3)" "unprognostic (2.43e-3)" "unprognostic (1.63e-1)" "unprognostic (2.44e-1)" "unprognostic (6.14e-4)" "unprognostic (4.41e-2)" "unprognostic (8.10e-3)" "unprognostic (2.72e-1)" "unprognostic (1.36e-1)" "unprognostic (1.89e-1)" "unprognostic (4.56e-3)" 0.3 1.2 13.4 0.7 15.3 0.2 0.3 4.9 17.1 0.2 2.3 1.0 0.9 0.1 1.0 0.6 0.2 15.0 21.0 17.2 7.1 0.9 0.2 1.8 0.2 5.8 7.4 10.4 0.2 0.0 0.5 0.3 5.8 4.7 1.2 6.6 0.1 5.1 0.1 0.2 3.0 0.1 7.0 0.8 1.3 0.7 8.5 0.0 1.0 0.3 0.9 1.4 0.3 15.9 0.0 0.0 18.3 0.0 0.5 8.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.6 1.1 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.9 0.0 0.0 0.0 0.2 0.0 8.4 0.0 1.9 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 13.4 15.3 4.9 17.1 17.2 7.1 5.8 7.4 5.8 7.0 8.5 15.9 0.6 0.0 0.5 1.6 0.9 0.3 0.1 0.0 0.6 46.6 0.0 0.1 34.4 11.5 0.0 1.8 4.2 0.0 0.2 0.1 0.0 0.1 0.0 0.3 1.3 1.1 3.0 0.8 27.6 0.0 0.0 2.0 0.0 0.9 2.5 0.4 0.7 0.1 0.3 8.4 28.3 0.7 0.0 0.6 0.3 0.7 31.7 0.7 0.0 4.7 0.0 2.4 0.0 12.1 9.3 0.5 0.1 21.1 0.4 0.1 3.4 0.1 2.2 6.2 0.0 0.3 1.2 0.0 0.0 0.3 0.3 0.0 4.9 0.3 0.5 0.0 BACE1 BACE ENSG00000186318 "Beta-secretase 1" P56817 11 117285207-117316259 "Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Aspartyl protease, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 119.1;pancreas: 271.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 118.9;Early spermatids: 99.9;Late spermatids: 343.0;Oligodendrocytes: 99.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 88.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB016358 Approved Supported "Plasma membrane" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "CAB016358: AB_626716" "unprognostic (7.96e-3)" "unprognostic (8.05e-2)" "unprognostic (3.55e-2)" "unprognostic (3.05e-3)" "unprognostic (8.94e-2)" "unprognostic (3.39e-1)" "unprognostic (1.03e-1)" "unprognostic (2.60e-1)" "unprognostic (4.54e-2)" "unprognostic (8.04e-2)" "unprognostic (8.09e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-1)" "unprognostic (1.35e-2)" "unprognostic (1.16e-1)" "unprognostic (1.27e-1)" "prognostic unfavorable (6.76e-4)" 15.4 16.0 34.3 8.0 68.5 3.3 11.7 68.7 44.0 18.3 11.9 13.7 6.1 19.7 8.8 13.5 15.9 19.1 11.4 34.3 44.5 14.8 25.6 14.4 5.1 89.7 67.0 20.5 271.5 18.5 10.7 13.8 76.6 13.4 7.6 44.7 11.0 18.3 12.5 11.4 7.7 21.3 61.6 12.4 9.8 11.2 59.9 3.8 12.2 9.1 5.0 12.4 14.3 119.1 11.5 10.7 22.9 37.3 80.9 82.3 1.0 62.9 44.4 24.4 19.0 4.5 16.4 1.4 14.6 88.3 18.4 17.9 24.3 12.1 20.5 3.1 12.1 6.0 17.3 5.1 36.5 2.5 1.7 68.1 20.2 29.7 31.8 68.0 21.4 3.8 2.7 1.1 46.5 33.4 2.5 2.1 15.5 10.6 25.9 6.4 11.6 1.6 12.2 5.9 31.7 36.7 22.5 2.6 5.9 23.5 26.2 7.6 31.4 45.2 5.0 48.2 19.4 0.7 1.0 1.1 23.8 2.0 34.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 34.3 68.5 68.7 44.0 34.3 44.5 89.7 67.0 76.6 61.6 59.9 119.1 12.1 19.2 10.1 16.3 0.3 4.7 4.1 3.4 9.1 53.7 8.7 9.0 8.7 18.6 13.3 5.5 118.9 1.0 0.1 2.0 5.9 7.4 99.9 5.1 32.1 8.3 21.7 1.7 24.9 20.0 1.3 19.5 3.1 8.9 2.5 15.8 6.8 38.6 9.4 57.2 32.0 5.1 2.0 17.2 7.7 343.0 19.3 7.9 3.6 14.0 4.0 17.9 0.0 22.1 99.8 4.3 6.3 22.2 0.1 2.4 1.7 6.3 3.4 55.2 6.6 18.1 14.2 3.4 1.7 10.6 3.4 0.8 1.2 68.0 4.5 3.4 BASP1 "CAP-23, CAP23, NAP-22, NAP22" ENSG00000176788 "Brain abundant membrane attached signal protein 1" P80723 5 17065598-17276843 "Plasma proteins, Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "brain: 486.3;epididymis: 303.3" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 345.6;Extravillous trophoblasts: 362.9;Langerhans cells: 489.4;Muller glia cells: 796.9;Syncytiotrophoblasts: 738.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "neutrophil: 128.5" "Lineage enriched" "Detected in many" 16 "granulocytes: 128.5" "Cell line enhanced" "Detected in many" "GAMG: 467.0;HeLa: 800.8;SiHa: 830.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA045218, HPA050333" Enhanced Enhanced "Plasma membrane" NA NA 63000000 "Cluster 50: Neutrophils - Cellular senescence" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA045218: AB_2679263, HPA050333: AB_2681090" "unprognostic (3.35e-2)" "unprognostic (3.13e-2)" "unprognostic (1.04e-1)" "unprognostic (1.32e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (5.63e-4)" "unprognostic (2.40e-1)" "unprognostic (1.02e-2)" "unprognostic (2.39e-1)" "unprognostic (1.89e-1)" "unprognostic (2.52e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (5.25e-11)" "unprognostic (1.95e-3)" "unprognostic (1.04e-1)" "unprognostic (3.61e-2)" "unprognostic (1.70e-1)" 35.3 13.8 235.9 73.6 257.0 87.6 14.0 103.0 486.3 56.9 79.9 12.5 7.3 37.3 303.3 10.9 11.4 29.2 13.9 247.3 210.9 15.1 17.2 36.5 80.9 134.7 153.1 36.6 3.7 3.4 21.2 92.1 184.3 79.7 10.8 74.3 13.2 21.6 2.3 22.0 22.2 33.4 107.7 76.5 22.7 2.9 157.1 24.1 11.3 6.8 91.5 57.9 27.3 281.8 0.1 125.6 152.7 0.2 71.7 76.1 227.1 161.7 50.9 127.9 135.0 6.1 0.1 51.3 22.4 112.0 467.0 10.6 98.2 109.2 164.8 21.3 57.9 0.4 800.8 0.3 158.9 101.3 1.4 131.2 132.7 145.6 121.0 163.9 140.1 0.2 0.4 0.5 138.2 183.7 0.3 92.5 115.7 0.3 39.6 0.1 0.5 28.0 46.5 31.3 99.3 21.3 830.7 72.3 0.2 336.5 0.3 101.9 187.7 169.3 0.6 14.2 26.1 1.7 0.2 27.1 171.2 123.0 23.1 25.0 3.1 25.3 0.0 1.5 0.0 5.4 0.0 0.0 4.9 7.9 0.0 0.0 128.5 1.8 2.1 0.5 0.3 0.8 235.9 257.0 103.0 486.3 247.3 210.9 134.7 153.1 184.3 107.7 157.1 281.8 8.0 9.6 4.8 22.2 158.7 215.9 88.0 21.3 58.1 54.8 9.8 10.2 1.6 0.0 15.8 9.2 12.5 155.0 3.8 0.6 0.0 0.6 0.9 98.4 345.6 30.2 0.0 18.1 254.0 3.4 362.9 102.6 23.4 156.4 27.3 18.1 35.7 2.5 53.8 244.0 125.3 0.7 12.2 227.9 489.4 0.0 0.6 298.5 28.4 53.4 275.1 796.9 1.0 115.1 23.7 1.0 0.2 0.0 173.0 121.0 0.0 0.3 93.5 58.4 0.0 2.0 66.2 0.4 3.4 21.0 58.8 738.5 11.9 8.3 1.8 13.2 BIN2 BRAP-1 ENSG00000110934 "Bridging integrator 2" Q9UBW5 12 51281038-51324668 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 101.3;lymphoid tissue: 48.7" "Cell type enhanced" "Detected in many" "dendritic cells: 213.6;Extravillous trophoblasts: 172.1;NK-cells: 598.3;Syncytiotrophoblasts: 158.6;T-cells: 165.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 82.6;HMC-1: 134.9;Karpas-707: 59.1;NB-4: 140.8;RPMI-8226: 55.4;THP-1: 117.4;U-937: 76.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038666, HPA038667" Enhanced Enhanced "Plasma membrane" NA NA 19000000 "Cluster 38: Basophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA038666: AB_2676139, HPA038667: AB_2676140" "unprognostic (8.44e-3)" "prognostic favorable (1.33e-4)" "unprognostic (2.48e-1)" "prognostic favorable (6.34e-4)" "unprognostic (4.63e-1)" "unprognostic (2.00e-3)" "unprognostic (1.21e-1)" "unprognostic (3.59e-2)" "unprognostic (3.72e-2)" "unprognostic (7.47e-2)" "unprognostic (5.71e-2)" "unprognostic (3.29e-1)" "unprognostic (1.65e-3)" "unprognostic (4.03e-1)" "unprognostic (3.96e-2)" "unprognostic (1.24e-1)" "unprognostic (2.22e-1)" 7.1 3.7 3.6 32.5 3.5 101.3 3.3 3.6 4.8 3.6 4.2 8.9 6.2 2.1 1.0 3.2 3.1 9.2 2.3 3.2 3.8 3.0 7.3 16.4 41.9 5.9 4.7 1.7 1.3 1.0 1.1 19.5 5.1 2.1 9.2 0.4 3.4 2.0 1.5 1.3 10.7 6.4 4.4 48.7 7.4 7.9 6.4 48.6 2.2 4.3 36.4 10.1 2.0 6.2 0.1 0.1 0.0 0.0 0.0 0.0 39.9 0.0 0.0 0.0 0.0 0.1 0.0 3.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 38.3 0.1 82.6 0.0 0.0 0.0 34.7 134.9 0.0 0.0 0.0 0.0 0.0 0.0 25.1 0.1 59.1 0.0 0.5 24.2 140.8 0.1 0.1 0.0 0.0 0.0 55.4 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.2 117.4 0.1 0.0 0.1 0.1 0.1 31.5 0.1 8.0 0.1 76.8 0.0 663.7 199.8 245.9 281.0 311.8 227.7 49.2 188.9 237.2 107.2 74.0 145.4 193.5 380.1 235.6 411.7 39.7 267.1 479.5 3.6 3.5 3.6 4.8 3.2 3.8 5.9 4.7 5.1 4.4 6.4 6.2 1.5 3.2 17.6 1.3 54.0 0.6 0.1 0.0 0.0 0.1 1.3 1.5 0.6 1.5 2.6 1.8 0.0 103.9 213.6 4.5 17.6 0.1 26.5 0.1 0.2 3.5 1.2 16.2 0.7 0.0 172.1 2.7 3.1 0.2 56.3 0.1 8.2 1.2 56.9 0.0 0.6 8.5 0.0 73.0 22.3 25.7 0.6 111.2 1.8 44.0 77.6 0.0 598.3 2.0 0.6 0.0 4.6 0.4 51.3 0.1 0.1 1.6 3.7 0.1 0.0 1.0 0.9 39.6 11.3 0.4 0.6 158.6 165.7 0.1 5.4 0.1 BTN2A1 "BT2.1, BTF1, BTN2.1" ENSG00000112763 "Butyrophilin subfamily 2 member A1" Q7KYR7 6 26457904-26476621 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA019208 Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA019208: AB_1845492" "unprognostic (1.86e-1)" "unprognostic (3.48e-1)" "unprognostic (1.20e-1)" "unprognostic (2.87e-1)" "unprognostic (2.29e-1)" "unprognostic (6.17e-2)" "unprognostic (5.74e-3)" "unprognostic (1.22e-2)" "unprognostic (1.03e-1)" "unprognostic (3.26e-2)" "unprognostic (6.90e-3)" "unprognostic (5.14e-2)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.97e-1)" "unprognostic (4.89e-2)" "unprognostic (7.92e-2)" "prognostic favorable (4.52e-5)" 16.1 17.3 10.8 11.4 10.7 16.8 13.3 19.9 13.1 15.5 11.4 17.7 9.8 16.7 8.3 8.9 16.1 10.2 16.0 11.1 15.2 13.6 9.1 18.4 13.9 12.1 13.2 15.2 8.9 4.8 11.9 19.0 13.7 13.3 11.0 4.5 9.5 14.4 11.7 8.2 15.0 16.9 12.0 25.7 12.2 11.7 13.5 10.6 10.5 10.1 11.4 17.3 13.3 12.2 16.4 14.5 28.9 18.3 12.7 10.2 1.4 36.1 30.1 42.3 38.7 13.5 11.0 13.3 47.3 24.5 54.9 7.0 22.1 8.9 40.2 18.4 21.6 7.9 15.3 16.0 19.9 11.8 21.2 13.9 8.2 47.1 15.2 25.1 15.3 25.4 13.5 20.6 35.7 6.7 19.9 18.2 9.7 4.8 11.9 17.0 27.3 13.6 16.5 7.3 28.9 16.4 11.2 14.8 26.4 17.8 4.3 9.9 21.3 32.1 16.6 28.1 40.8 16.1 40.4 11.1 12.8 22.0 52.1 43.6 9.0 30.2 11.1 5.2 9.8 8.6 9.3 12.4 8.4 6.2 8.6 11.0 51.7 9.9 8.8 8.9 16.0 7.2 10.8 10.7 19.9 13.1 11.1 15.2 12.1 13.2 13.7 12.0 13.5 12.2 21.2 16.0 14.7 7.5 20.0 8.0 8.0 8.5 9.1 8.0 11.8 10.9 17.6 7.2 11.7 9.2 6.2 6.1 35.4 16.0 3.9 10.9 3.2 18.1 17.7 22.1 9.0 4.6 8.9 12.8 11.2 14.7 18.8 20.8 24.6 13.3 21.8 6.2 11.6 3.3 10.2 14.8 12.2 17.9 16.7 6.2 12.8 18.4 10.6 10.3 21.9 6.0 25.7 10.6 7.8 16.4 10.2 12.8 18.9 13.1 11.4 4.7 26.9 2.3 39.5 12.4 24.4 8.7 12.9 7.3 8.1 11.8 25.0 14.9 12.9 17.9 C1orf54 FLJ23221 ENSG00000118292 "Chromosome 1 open reading frame 54" Q8WWF1 1 150268200-150280916 "Predicted secreted proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Endothelial cells: 101.3;Kupffer cells: 145.7;Langerhans cells: 282.7;Leydig cells: 95.1;Peritubular cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 5 "myeloid DC: 103.5" "Lineage enriched" "Detected in many" 5 "dendritic cells: 103.5" "Cell line enhanced" "Detected in many" "AF22: 77.8;AN3-CA: 110.5;ASC diff: 86.1;ASC TERT1: 141.3;HSkMC: 102.1;HUVEC TERT2: 108.4;U-87 MG: 68.3" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA026518, HPA043874" Approved Approved "Plasma membrane" "Secreted to blood" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA026518: AB_1845647, HPA043874: AB_2732511" "unprognostic (4.64e-3)" "unprognostic (6.81e-3)" "unprognostic (4.01e-3)" "unprognostic (5.69e-3)" "unprognostic (2.22e-1)" "unprognostic (1.72e-1)" "unprognostic (1.51e-2)" "unprognostic (1.88e-1)" "unprognostic (1.26e-1)" "unprognostic (1.33e-1)" "unprognostic (3.45e-1)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.43e-4)" "unprognostic (3.16e-2)" "unprognostic (8.06e-2)" "unprognostic (1.33e-2)" "unprognostic (4.48e-2)" 37.6 19.1 59.8 26.4 60.7 11.9 30.7 62.0 96.2 27.6 56.2 25.9 13.3 30.1 39.1 17.9 33.2 46.4 34.6 57.6 62.2 28.4 29.7 29.2 62.6 61.9 61.8 7.9 5.1 14.5 10.5 59.2 62.0 28.7 25.9 16.2 8.4 75.6 24.6 11.1 15.0 60.3 63.5 69.4 12.7 13.9 64.2 30.8 13.9 48.3 27.9 36.2 18.2 62.4 1.6 0.3 77.8 110.5 86.1 141.3 2.2 14.0 20.5 3.8 12.0 0.9 1.9 0.6 4.1 12.3 1.5 2.7 0.2 0.5 5.6 1.4 12.2 1.9 2.0 1.3 17.7 3.9 2.6 102.1 5.9 24.8 1.9 13.2 108.4 1.8 1.8 12.2 15.0 4.2 0.7 24.0 5.7 0.1 3.9 18.8 1.7 1.4 1.1 6.1 1.5 1.3 1.4 0.8 7.5 16.4 1.4 58.0 0.7 28.1 2.1 0.8 0.9 5.0 4.8 1.2 68.3 3.1 0.7 0.1 21.2 0.8 0.6 20.8 2.5 0.9 3.8 1.7 103.5 0.7 3.5 2.0 1.0 0.8 5.6 2.1 1.9 6.4 59.8 60.7 62.0 96.2 57.6 62.2 61.9 61.8 62.0 63.5 64.2 62.4 115.7 3.2 4.5 19.6 3.3 6.4 2.2 2.4 1.8 0.8 2.3 3.7 10.6 2.8 2.5 22.0 0.0 1.3 1.5 2.0 76.3 0.7 9.4 3.1 37.6 101.3 1.2 0.4 4.1 2.3 0.8 29.3 5.1 3.1 1.3 0.7 51.8 1.3 45.3 0.0 3.8 1.3 0.0 145.7 282.7 19.6 95.1 65.6 12.4 16.9 24.9 23.4 1.0 0.5 0.3 2.0 1.5 104.2 3.0 4.9 2.7 4.9 0.5 1.6 32.9 7.5 70.4 16.6 1.9 7.5 5.1 3.6 3.3 5.2 1.4 8.4 C2CD2L "KIAA0285, TMEM24" ENSG00000172375 "C2CD2 like" O14523 11 119102198-119118544 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 37.5;Distal enterocytes: 40.6;Proximal enterocytes: 33.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HMC-1: 50.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011044, HPA075369" Approved Supported "Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 3: HMC-1 - Innate immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA011044: AB_2668414, HPA075369: " "unprognostic (3.43e-2)" "unprognostic (2.81e-2)" "unprognostic (1.03e-3)" "prognostic favorable (4.92e-4)" "unprognostic (3.18e-2)" "unprognostic (1.19e-1)" "unprognostic (2.25e-3)" "unprognostic (3.37e-3)" "unprognostic (5.28e-2)" "unprognostic (2.09e-1)" "unprognostic (3.99e-3)" "unprognostic (8.19e-2)" "prognostic unfavorable (1.75e-4)" "unprognostic (8.02e-2)" "unprognostic (8.32e-3)" "unprognostic (4.10e-2)" "unprognostic (2.60e-1)" 6.6 8.2 26.9 6.5 27.6 13.6 5.8 15.5 28.9 6.4 15.3 11.1 16.1 6.2 4.8 10.8 8.8 5.3 10.2 26.8 19.6 11.6 13.1 10.3 8.1 18.0 18.4 6.0 11.0 5.7 23.9 3.9 18.4 7.1 7.3 14.1 9.6 5.3 15.3 15.3 17.1 5.1 15.2 14.9 8.1 4.3 21.4 8.5 6.7 7.3 5.7 7.0 6.6 23.7 6.1 4.5 6.0 12.5 7.7 3.2 3.9 9.0 7.8 8.7 7.2 7.3 6.3 9.1 23.1 6.3 9.1 13.4 7.6 3.9 3.4 14.3 6.2 35.7 5.9 5.3 10.2 10.5 50.5 3.7 7.9 16.4 6.1 9.8 5.4 13.5 15.1 16.1 8.3 16.2 11.9 24.9 2.2 15.0 11.8 7.4 5.3 10.5 8.7 3.8 18.7 10.5 3.8 20.1 5.9 2.3 35.3 13.9 6.7 8.1 2.8 9.9 16.1 6.8 4.5 3.5 4.9 17.6 9.1 0.5 1.3 2.7 0.2 1.4 0.4 0.1 0.6 0.6 0.5 0.0 0.6 0.3 0.4 0.8 2.0 0.3 0.6 0.5 26.9 27.6 15.5 28.9 26.8 19.6 18.0 18.4 18.4 15.2 21.4 23.7 5.1 6.4 4.2 9.4 3.7 10.7 1.6 2.3 10.2 15.6 6.8 5.0 2.4 2.8 4.3 1.8 37.5 0.9 7.4 40.6 3.9 3.4 5.4 12.1 2.6 5.7 1.2 7.0 15.1 2.8 1.7 2.5 3.6 4.6 2.5 2.2 11.4 5.4 9.4 21.9 15.0 8.0 0.0 13.9 16.1 1.3 2.1 11.4 7.2 5.6 15.3 5.9 7.2 4.5 8.4 5.1 10.4 1.5 7.2 3.2 33.0 4.0 21.9 29.9 6.6 2.1 3.6 3.7 2.0 10.3 10.9 1.1 8.6 3.6 5.5 1.9 CA14 ENSG00000118298 "Carbonic anhydrase 14" Q9ULX7 1 150257251-150265078 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 33.3;retina: 39.4;skeletal muscle: 33.7;tongue: 47.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 69.5;Melanocytes: 53.4;Muller glia cells: 164.5;Oligodendrocytes: 25.7" "Cancer enriched" "Detected in many" 5 "melanoma: 23.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "AF22: 102.2;AN3-CA: 65.9;NTERA-2: 83.9;SK-MEL-30: 217.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008482 Approved Approved "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA008482: AB_1078395" "unprognostic (3.06e-2)" "unprognostic (1.67e-1)" "unprognostic (2.10e-2)" "unprognostic (3.25e-2)" "prognostic favorable (8.47e-4)" "unprognostic (7.28e-2)" "unprognostic (4.48e-2)" "unprognostic (1.49e-1)" "unprognostic (2.10e-1)" "unprognostic (2.47e-1)" "unprognostic (5.46e-2)" "unprognostic (1.73e-1)" "unprognostic (5.89e-3)" "unprognostic (1.91e-1)" "unprognostic (1.49e-1)" "unprognostic (1.22e-1)" "unprognostic (5.80e-2)" 0.0 0.2 8.6 0.2 14.4 1.2 0.3 15.9 27.6 0.1 33.3 3.8 0.4 0.1 0.4 1.9 1.7 0.6 7.6 8.7 11.3 0.3 8.7 0.2 0.1 14.3 14.0 1.4 0.2 3.4 0.5 0.3 14.6 4.0 0.7 39.4 0.4 20.3 33.7 5.4 1.3 0.5 12.5 0.2 1.2 0.5 13.3 0.0 1.0 47.4 0.0 0.6 0.1 20.6 0.9 0.2 102.2 65.9 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.7 0.1 0.5 0.0 0.1 0.3 0.2 0.1 0.0 0.2 1.1 0.3 0.3 6.9 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.1 0.6 0.0 0.9 0.3 0.3 83.9 0.4 1.1 0.1 0.3 0.3 0.0 0.2 3.2 1.8 0.0 0.3 217.9 14.6 0.8 0.4 0.1 0.1 0.2 0.2 0.4 0.9 4.9 0.4 0.7 0.5 0.2 0.0 0.2 0.4 0.4 0.5 0.1 0.5 0.2 0.3 0.0 0.6 0.3 0.3 0.5 0.0 0.1 0.6 0.0 0.0 8.6 14.4 15.9 27.6 8.7 11.3 14.3 14.0 14.6 12.5 13.3 20.6 0.1 3.2 0.5 0.3 0.2 2.2 0.3 0.3 0.0 1.3 0.1 0.0 69.5 0.0 0.7 0.0 0.0 0.4 0.0 0.3 0.0 0.8 0.0 0.3 0.1 0.6 0.0 0.0 0.1 0.7 0.1 3.4 0.0 0.2 0.0 0.0 0.0 6.1 0.1 0.0 0.1 0.3 0.0 0.3 0.9 0.2 0.9 0.1 53.4 0.0 0.0 164.5 0.0 0.0 25.7 1.9 0.3 3.4 0.0 0.3 0.0 0.1 0.1 4.9 0.0 0.6 0.5 0.0 0.2 0.0 0.4 0.3 0.1 0.0 0.2 0.5 CA9 "CAIX, MN" ENSG00000107159 "Carbonic anhydrase 9" Q16790 9 35673918-35681159 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Lyase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "stomach 1: 289.3" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 275.3;Cholangiocytes: 62.9;Early spermatids: 205.8;Gastric mucus-secreting cells: 259.5" "Cancer enhanced" "Detected in many" "renal cancer: 85.9" "Region enriched" "Detected in single" 9 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A-431: 189.3;HDLM-2: 98.1;hTERT-RPE1: 113.1;U-87 MG: 374.4" "Region enhanced" "Detected in many" "cerebellum: 12.3" "Low region specificity" "Detected in all" "CAB005100, CAB017107, HPA055207" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB005100: AB_2066539, CAB017107: , HPA055207: AB_2682738" "unprognostic (8.01e-3)" "unprognostic (1.34e-2)" "unprognostic (2.28e-1)" "unprognostic (2.00e-2)" "unprognostic (1.59e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.71e-5)" "unprognostic (1.47e-2)" "unprognostic (3.90e-2)" "unprognostic (1.29e-1)" "unprognostic (6.24e-3)" "unprognostic (1.13e-1)" "prognostic unfavorable (2.22e-7)" "unprognostic (7.29e-2)" "prognostic favorable (9.50e-4)" "unprognostic (2.97e-3)" "unprognostic (8.67e-2)" 3.8 0.4 0.0 0.2 0.0 0.0 0.1 5.6 0.6 0.5 0.0 0.6 14.5 0.2 0.1 0.8 0.4 24.4 2.0 0.2 0.1 0.2 1.3 0.2 0.0 0.0 0.1 0.7 6.6 0.0 0.5 0.0 0.2 0.5 0.0 1.0 0.1 0.1 0.1 8.2 13.6 0.1 0.0 0.0 289.3 5.5 0.5 0.0 0.0 0.0 0.0 0.7 0.7 0.0 189.3 0.3 0.0 0.0 0.0 0.0 0.0 0.2 3.6 0.3 2.5 0.0 0.1 0.0 0.1 0.0 0.5 5.7 0.0 0.9 1.5 98.1 0.0 0.0 0.7 0.4 0.0 0.0 0.2 0.4 0.0 0.0 0.3 113.1 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.3 0.2 0.5 0.0 0.0 10.6 0.0 0.6 1.6 0.0 0.0 0.1 0.7 0.0 0.0 0.2 0.0 18.9 0.4 0.0 4.7 0.0 0.4 0.1 374.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 5.6 0.6 0.2 0.1 0.0 0.1 0.2 0.0 0.5 0.0 0.2 0.0 0.0 0.0 0.2 4.5 0.7 275.3 0.0 0.4 0.1 0.0 0.4 62.9 28.1 0.0 0.0 0.0 0.0 0.1 0.0 49.1 205.8 0.0 0.1 0.2 0.0 0.0 0.1 50.9 0.6 1.2 259.5 0.2 0.0 0.4 0.7 0.0 0.1 0.0 0.6 4.0 18.3 0.0 0.0 19.6 1.5 0.1 0.0 0.0 0.6 1.3 0.0 0.0 0.0 26.6 0.0 0.7 0.3 0.8 0.7 0.1 5.5 0.0 0.0 0.0 1.5 0.9 4.0 0.0 3.1 0.3 0.1 0.7 5.3 0.4 CALCRL "CGRPR, CRLR" ENSG00000064989 "Calcitonin receptor like receptor" Q16602 2 187341964-187448460 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 70.7;lung: 76.8" "Cell type enhanced" "Detected in many" "Adipocytes: 138.3;Endometrial stromal cells: 92.7;Endothelial cells: 248.7;Hepatic stellate cells: 259.2;Oligodendrocyte precursor cells: 293.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 2.6;myeloid DC: 9.2;plasmacytoid DC: 2.6" "Group enriched" "Detected in many" 6 "dendritic cells: 9.2;monocytes: 2.6" "Cell line enriched" "Detected in some" 4 "HUVEC TERT2: 173.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008070, HPA046515" Uncertain Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA008070: AB_1845912, HPA046515: AB_2679681" "unprognostic (7.06e-2)" "unprognostic (5.71e-2)" "unprognostic (1.59e-1)" "unprognostic (2.13e-1)" "unprognostic (3.44e-3)" "unprognostic (7.60e-3)" "unprognostic (9.25e-3)" "unprognostic (4.14e-2)" "unprognostic (7.71e-3)" "unprognostic (3.32e-1)" "unprognostic (3.77e-1)" "unprognostic (3.44e-1)" "unprognostic (1.51e-3)" "unprognostic (1.90e-2)" "unprognostic (2.02e-1)" "unprognostic (1.30e-1)" "unprognostic (2.50e-2)" 70.7 6.3 3.4 12.3 4.0 0.4 15.8 6.1 4.4 27.8 3.4 6.9 6.0 21.5 4.6 8.6 11.4 24.4 20.4 3.9 3.8 14.0 12.6 76.8 7.9 11.1 6.2 15.7 4.3 13.0 3.6 11.7 10.8 7.3 9.5 0.9 7.1 7.7 6.2 3.9 6.3 27.1 15.5 8.6 7.1 2.7 3.9 4.6 28.3 20.2 9.1 14.1 4.7 15.2 0.2 0.0 8.8 0.0 6.2 1.6 0.0 0.8 1.3 0.1 1.0 0.0 1.0 0.0 2.3 0.7 0.2 0.0 0.0 0.6 0.2 1.5 0.5 1.5 0.0 0.2 4.9 0.2 0.0 4.6 0.2 0.3 2.1 0.5 173.6 0.1 0.0 2.5 1.2 0.0 0.8 0.1 0.5 0.0 0.0 0.0 3.1 0.5 40.5 0.0 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.2 25.3 0.7 0.1 0.1 0.4 6.2 0.1 0.7 0.4 0.0 0.0 0.0 2.6 0.0 0.0 0.5 0.0 0.2 0.0 0.0 9.2 0.0 0.8 0.1 0.1 1.0 1.0 2.6 0.0 0.9 3.4 4.0 6.1 4.4 3.9 3.8 11.1 6.2 10.8 15.5 3.9 15.2 138.3 0.0 11.9 19.6 1.2 9.3 2.3 1.7 21.6 0.2 0.8 1.8 12.3 2.8 3.6 0.0 0.0 0.4 2.4 0.0 3.9 0.3 0.8 3.1 92.7 248.7 0.0 4.8 15.4 0.4 0.2 56.5 1.1 1.7 5.1 12.3 259.2 1.8 0.9 0.0 2.1 0.0 2.0 10.3 29.7 1.0 7.8 15.4 10.6 47.8 16.1 0.0 1.0 293.0 1.0 0.1 0.0 2.6 4.9 1.9 0.0 13.2 2.8 0.1 6.6 4.1 21.5 1.3 0.7 18.2 6.8 0.3 3.0 6.0 0.0 1.8 CALHM4 "C6orf78, FAM26D, FLJ32239" ENSG00000164451 "Calcium homeostasis modulator family member 4" Q5JW98 6 116529013-116558868 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "placenta: 23.1" "Group enriched" "Detected in some" 24 "Cytotrophoblasts: 28.2;Syncytiotrophoblasts: 54.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "SuSa: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA048014 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA048014: " "unprognostic (7.95e-2)" "unprognostic (3.44e-4)" "unprognostic (1.99e-1)" "unprognostic (1.44e-2)" 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.0 23.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 4.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 54.6 0.0 0.2 0.0 0.0 CASKIN2 "ANKS5B, FLJ21609, KIAA1139" ENSG00000177303 "CASK interacting protein 2" Q8WXE0 17 75500261-75515537 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 75.5;Endothelial cells: 42.2;Hepatic stellate cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA071906, HPA075184" Enhanced Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA071906: AB_2732191, HPA075184: AB_2732281" "unprognostic (1.60e-1)" "unprognostic (4.54e-2)" "unprognostic (9.12e-3)" "unprognostic (5.27e-3)" "unprognostic (9.32e-2)" "unprognostic (5.78e-2)" "unprognostic (2.87e-2)" "unprognostic (4.10e-2)" "unprognostic (7.67e-2)" "unprognostic (1.33e-1)" "prognostic favorable (2.47e-5)" "unprognostic (1.82e-2)" "prognostic favorable (4.83e-8)" "unprognostic (1.43e-1)" "unprognostic (1.52e-1)" "unprognostic (1.39e-1)" "unprognostic (4.95e-2)" 33.8 22.7 19.4 4.9 22.6 0.4 30.0 19.7 18.6 15.1 4.6 16.5 9.0 21.0 2.7 10.8 21.7 11.2 28.2 16.7 17.2 26.9 11.3 42.3 2.9 22.6 21.7 12.0 10.8 9.4 13.6 11.8 18.7 14.9 2.9 4.8 11.5 8.7 15.3 12.7 11.4 10.4 18.1 30.8 15.0 5.6 20.0 2.9 22.6 9.9 1.5 16.0 14.3 23.1 13.3 17.2 10.2 14.4 6.6 4.1 11.2 6.6 8.7 15.8 10.2 19.0 5.6 0.5 7.4 7.7 10.5 12.0 8.2 7.7 3.9 4.7 10.8 9.4 17.2 7.5 7.7 0.5 12.6 3.5 10.4 8.2 5.9 5.3 16.2 13.3 6.9 1.6 5.0 31.1 24.3 0.7 7.5 10.3 17.5 12.8 21.8 2.1 10.2 13.4 10.4 10.2 13.9 18.7 11.0 8.7 13.7 4.0 13.9 16.1 14.6 7.9 8.7 1.2 5.9 1.5 5.6 0.3 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.4 22.6 19.7 18.6 16.7 17.2 22.6 21.7 18.7 18.1 20.0 23.1 75.5 3.2 2.2 11.1 1.3 8.0 2.5 3.5 6.8 6.5 5.8 5.0 11.4 2.8 1.8 9.2 10.4 2.2 0.6 11.7 3.9 5.1 0.5 2.8 4.4 42.2 7.7 8.0 1.3 5.3 1.9 6.0 8.2 5.7 0.0 14.9 56.7 6.8 2.7 3.3 1.7 4.3 8.2 4.1 3.1 2.3 8.1 1.2 1.8 7.5 2.0 28.2 0.0 15.1 8.3 6.0 6.0 11.3 1.6 2.5 8.4 3.1 1.4 6.8 0.0 5.5 6.4 2.7 4.4 4.5 7.0 2.2 0.5 5.7 4.6 2.2 CAVIN3 "cavin-3, HSRBC, MGC20400, PRKCDBP, SRBC" ENSG00000170955 "Caveolae associated protein 3" Q969G5 11 6318946-6320532 "Predicted intracellular proteins" "Biological rhythms" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 140.5;Exocrine glandular cells: 252.2;Extravillous trophoblasts: 88.9;Fibroblasts: 88.7;Pancreatic endocrine cells: 219.0;Smooth muscle cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 16.2;myeloid DC: 42.8" "Group enriched" "Detected in many" 5 "dendritic cells: 42.8;monocytes: 16.2" "Cell line enhanced" "Detected in many" "A-431: 120.7;BJ: 111.6;HaCaT: 91.7;TIME: 133.6;U-87 MG: 125.9;WM-115: 137.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055136, HPA073327" Supported Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA055136: AB_2682711, HPA073327: AB_2686595" "unprognostic (7.92e-2)" "prognostic unfavorable (3.75e-5)" "unprognostic (3.12e-2)" "unprognostic (2.30e-1)" "unprognostic (4.69e-2)" "unprognostic (2.69e-1)" "unprognostic (2.24e-2)" "unprognostic (1.19e-3)" "unprognostic (2.49e-2)" "unprognostic (6.03e-3)" "unprognostic (3.37e-1)" "unprognostic (6.66e-2)" "prognostic unfavorable (5.21e-6)" "unprognostic (3.85e-2)" "unprognostic (1.70e-1)" "unprognostic (1.62e-1)" "unprognostic (1.96e-2)" 69.3 20.3 5.0 16.4 5.3 0.5 51.7 4.9 7.3 73.5 10.3 69.8 5.8 106.5 1.3 19.2 48.8 1.3 57.9 4.3 4.3 24.9 8.3 37.8 2.5 5.1 4.3 37.0 21.4 1.3 8.1 11.7 5.4 43.6 4.0 0.0 20.3 13.1 17.1 28.3 29.6 22.9 4.9 25.0 37.3 12.1 5.7 1.1 22.6 5.6 1.4 79.3 58.2 4.1 120.7 12.1 0.1 0.4 5.4 24.7 0.0 111.6 45.1 18.5 20.5 0.0 0.1 0.0 36.6 26.1 1.9 91.7 0.0 9.0 3.4 30.1 0.0 0.0 14.0 0.0 14.6 0.0 0.5 16.6 12.4 6.9 9.0 0.0 35.7 0.0 0.0 0.7 19.8 0.0 0.0 0.1 74.6 0.9 2.0 0.0 0.0 0.2 25.6 0.0 0.0 0.1 40.9 0.2 27.0 0.7 0.2 0.5 133.6 0.0 0.4 46.0 0.4 0.2 1.0 0.2 125.9 0.0 137.7 0.0 16.2 0.0 0.0 1.1 0.0 0.0 0.8 0.0 42.8 0.0 0.0 0.0 0.2 0.4 0.0 0.0 6.1 5.9 5.0 5.3 4.9 7.3 4.3 4.3 5.1 4.3 5.4 4.9 5.7 4.1 140.5 12.8 6.9 0.0 2.4 0.0 0.0 0.0 0.0 0.0 7.7 36.2 0.0 0.0 8.1 16.5 0.0 3.6 1.0 0.0 39.2 6.0 0.0 6.9 59.7 70.3 0.0 0.0 0.0 252.2 88.9 88.7 0.0 8.0 0.0 2.6 0.0 0.0 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 30.5 0.0 0.0 0.0 0.0 219.0 0.0 0.0 0.5 0.0 0.0 47.6 10.2 0.0 0.0 0.0 146.0 0.0 0.0 0.0 0.0 8.5 1.6 45.7 0.0 0.0 CBWD1 ENSG00000172785 "COBW domain containing 1" Q9BRT8 9 121038-179147 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 185.1" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (3.75e-2)" "unprognostic (3.47e-2)" "unprognostic (5.23e-2)" "unprognostic (4.15e-2)" "unprognostic (1.39e-1)" "unprognostic (2.67e-2)" "unprognostic (3.91e-2)" "unprognostic (3.72e-1)" "unprognostic (4.15e-2)" "unprognostic (2.07e-3)" "unprognostic (1.82e-1)" "unprognostic (4.68e-2)" "unprognostic (5.80e-7)" "unprognostic (7.19e-2)" "unprognostic (1.04e-1)" "unprognostic (8.94e-2)" "unprognostic (4.98e-3)" 18.6 34.4 8.7 15.3 9.2 13.0 19.9 10.6 11.1 14.3 13.0 16.9 13.3 13.7 20.8 26.8 14.6 10.6 20.7 9.0 10.2 40.1 26.8 16.1 13.4 9.0 9.0 15.4 30.0 38.3 19.4 22.2 9.2 19.9 15.2 27.5 23.7 12.2 21.8 22.3 14.1 12.2 9.0 16.9 19.1 16.4 9.1 13.2 25.4 17.6 20.1 23.4 17.1 9.9 43.3 16.1 22.7 12.2 29.1 26.2 50.3 22.2 14.6 30.4 23.0 23.4 16.1 39.4 28.3 8.2 18.4 7.3 11.3 21.1 32.4 67.8 38.9 0.4 39.1 72.6 31.5 115.1 17.2 23.5 9.9 7.3 59.0 19.5 32.9 19.7 13.6 84.3 25.2 52.1 25.1 185.1 22.9 37.6 34.6 47.7 34.6 75.8 39.4 120.7 40.8 24.8 45.8 16.8 17.8 55.5 35.6 109.2 34.4 16.0 22.9 20.8 19.7 10.1 14.6 44.6 39.6 60.6 19.2 3.6 65.7 19.3 10.3 75.6 16.9 21.1 18.6 16.8 74.1 15.7 16.2 17.7 10.2 12.8 60.8 19.6 18.1 48.3 8.7 9.2 10.6 11.1 9.0 10.2 9.0 9.0 9.2 9.0 9.1 9.9 19.5 54.5 50.1 8.1 41.2 47.7 29.9 47.6 97.9 50.8 49.4 37.6 51.8 30.0 49.8 35.0 108.4 96.3 17.7 20.4 35.2 79.9 51.7 14.9 10.1 23.0 31.2 44.6 17.0 118.5 41.2 23.0 34.7 11.9 32.8 26.7 20.7 19.0 32.0 38.7 17.1 39.0 50.8 25.1 38.0 16.4 18.0 37.9 32.0 18.7 81.5 32.2 18.6 5.5 16.7 66.9 38.2 13.2 90.0 32.0 49.5 73.6 31.0 63.5 32.9 20.2 27.8 48.6 28.1 83.8 50.6 124.8 23.5 24.1 62.3 24.9 CBWD2 ENSG00000136682 "COBW domain containing 2" Q8IUF1 2 113437691-113496204 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 110.3;Suprabasal keratinocytes: 120.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (4.67e-2)" "unprognostic (2.17e-1)" "unprognostic (4.14e-1)" "prognostic unfavorable (3.22e-5)" "unprognostic (7.69e-2)" "unprognostic (2.17e-1)" "unprognostic (2.16e-3)" "unprognostic (1.31e-3)" "unprognostic (3.69e-2)" "unprognostic (1.72e-2)" "unprognostic (5.85e-2)" "unprognostic (1.39e-1)" "unprognostic (8.50e-2)" "unprognostic (1.90e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (7.57e-3)" 4.7 8.3 5.8 5.3 6.3 1.5 7.0 7.0 7.2 8.2 7.1 8.4 2.2 7.0 7.1 9.4 4.5 4.5 15.9 6.3 6.7 13.8 10.5 4.0 3.2 6.0 6.2 5.4 5.6 16.2 8.8 5.9 6.1 6.4 5.9 6.3 8.1 7.4 26.0 4.3 4.6 8.1 5.5 4.9 6.5 2.0 6.0 6.8 9.6 23.9 4.6 8.7 5.4 6.4 16.1 9.7 9.8 11.2 25.7 11.8 19.2 11.9 7.4 9.1 12.0 16.0 9.6 20.7 36.2 12.8 42.1 13.2 10.8 13.2 12.0 7.5 28.9 17.4 16.8 29.8 8.6 8.1 7.8 11.1 8.1 13.4 8.1 17.7 17.1 11.1 10.1 22.2 13.4 17.1 23.3 24.2 11.9 30.2 20.7 10.9 26.6 54.6 24.6 25.1 28.0 8.0 31.4 4.6 5.1 33.7 14.5 21.6 20.8 7.7 10.7 4.8 11.9 8.5 38.2 10.5 12.8 44.5 19.3 15.6 67.7 35.6 12.1 68.4 13.2 17.9 18.2 14.3 65.3 22.7 15.3 14.1 18.5 20.2 56.2 16.2 27.0 52.9 5.8 6.3 7.0 7.2 6.3 6.7 6.0 6.2 6.1 5.5 6.0 6.4 5.6 9.6 20.5 11.8 32.5 110.3 12.8 24.5 62.6 10.5 15.9 14.9 49.6 18.6 20.0 14.7 16.7 17.6 7.1 7.2 39.2 29.6 18.6 10.3 7.1 11.9 2.4 23.7 27.3 14.3 13.2 16.4 23.0 11.1 15.8 9.5 6.1 11.4 9.0 13.5 25.8 11.4 16.2 9.4 62.5 18.4 10.8 20.0 26.6 21.5 53.8 10.9 2.1 15.6 24.9 12.7 14.1 17.3 78.7 14.9 13.7 33.9 26.4 14.0 0.0 9.6 17.1 21.7 13.6 61.0 120.0 25.9 18.4 11.6 17.3 12.2 CBWD3 bA561O23.1 ENSG00000196873 "COBW domain containing 3" Q5JTY5 9 68232003-68300035 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Uncertain Approved "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (1.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.95e-1)" "unprognostic (9.71e-3)" "unprognostic (9.99e-2)" "unprognostic (6.38e-2)" "unprognostic (3.44e-2)" "unprognostic (1.79e-2)" "unprognostic (3.54e-2)" "unprognostic (1.81e-1)" "unprognostic (1.05e-2)" "unprognostic (2.05e-2)" "unprognostic (1.05e-3)" "unprognostic (3.77e-2)" "unprognostic (1.67e-1)" "unprognostic (4.43e-3)" "unprognostic (5.16e-4)" 12.2 19.4 7.5 18.8 7.5 13.5 17.3 9.8 9.5 9.8 5.3 14.0 13.0 9.9 7.3 17.2 9.7 6.6 13.0 8.1 8.9 21.2 28.4 10.2 16.9 8.4 7.7 12.0 27.2 8.6 18.4 15.6 8.8 10.5 9.8 18.0 13.5 10.2 17.5 13.1 20.6 8.9 4.4 12.7 17.5 12.3 6.9 12.7 14.3 13.3 13.0 18.8 12.2 10.6 73.0 52.6 25.1 41.2 18.9 6.7 34.3 35.6 14.1 15.2 17.4 15.0 69.4 84.1 33.9 26.1 67.5 86.7 48.0 70.5 39.8 128.2 31.0 31.9 137.8 73.6 24.8 60.9 38.3 15.6 21.3 27.0 35.3 30.5 35.6 93.1 60.4 66.1 22.3 47.4 71.8 81.9 38.5 86.4 88.7 32.6 78.7 94.0 17.3 32.8 40.3 25.7 58.0 36.2 46.3 46.6 26.7 71.5 16.6 22.6 58.1 38.4 70.1 38.3 165.4 102.3 68.8 92.3 41.6 29.8 86.1 66.2 27.8 71.5 24.0 52.5 25.2 28.7 62.0 52.3 27.6 25.5 86.5 16.1 52.0 46.5 37.9 59.8 7.5 7.5 9.8 9.5 8.1 8.9 8.4 7.7 8.8 4.4 6.9 10.6 4.3 25.6 30.0 2.0 15.9 14.5 16.2 6.0 12.0 25.2 14.5 9.7 28.7 7.2 21.0 11.0 29.2 13.2 5.6 9.7 1.9 7.1 4.7 4.0 2.4 9.0 4.2 5.2 10.8 11.6 7.9 8.9 8.6 3.8 12.6 12.4 6.1 8.2 5.0 11.8 8.9 9.1 2.0 11.0 10.1 2.4 5.0 6.8 5.4 6.5 19.7 5.9 8.2 10.1 5.6 8.8 17.4 3.0 20.3 12.6 28.9 7.1 24.1 36.2 6.6 5.3 6.3 16.7 7.8 7.3 21.5 15.5 10.6 7.6 10.7 12.9 CBWD5 ENSG00000147996 "COBW domain containing 5" Q5RIA9 9 65668805-65734041 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal squamous epithelial cells: 178.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (8.18e-2)" "unprognostic (4.23e-3)" "unprognostic (5.25e-3)" "unprognostic (1.02e-3)" "unprognostic (5.32e-3)" "unprognostic (9.24e-2)" "unprognostic (2.07e-1)" "unprognostic (1.54e-2)" "unprognostic (1.11e-2)" "unprognostic (6.46e-3)" "unprognostic (1.03e-1)" "unprognostic (4.61e-3)" "unprognostic (1.17e-1)" "unprognostic (5.68e-2)" "unprognostic (3.87e-1)" 9.8 15.2 20.7 8.4 21.1 7.0 17.0 21.7 25.8 11.2 20.6 11.4 11.0 6.5 9.0 15.5 10.9 5.2 12.5 21.1 22.3 26.0 41.9 9.6 6.6 21.1 21.3 10.6 19.4 7.8 16.8 6.7 21.5 17.4 10.5 8.7 9.6 7.7 8.4 11.0 13.9 5.9 20.7 21.2 11.4 11.4 21.0 4.6 15.6 4.2 9.7 12.7 9.8 21.8 37.7 40.1 14.0 17.3 20.8 9.5 16.4 26.0 17.6 20.2 20.6 5.2 33.6 51.2 16.2 15.3 29.1 27.2 64.1 21.3 38.2 8.4 15.4 14.4 69.3 91.0 16.2 32.8 8.9 16.9 23.9 18.7 14.8 25.0 37.3 19.4 20.5 36.9 21.1 45.8 16.4 34.2 16.3 64.4 42.4 28.1 19.2 49.9 32.4 23.9 18.1 18.3 21.2 16.1 8.0 24.5 76.4 21.3 10.6 9.1 33.6 27.7 30.2 12.0 34.8 11.8 37.4 35.9 35.3 1.7 11.8 8.8 3.2 15.0 3.7 5.3 5.3 4.6 12.4 3.0 4.8 4.0 7.8 2.8 9.8 5.2 4.4 10.6 20.7 21.1 21.7 25.8 21.1 22.3 21.1 21.3 21.5 20.7 21.0 21.8 17.8 41.7 51.8 13.4 58.4 65.1 31.8 24.6 178.7 37.7 59.4 36.7 33.6 25.8 38.5 20.2 68.8 44.0 10.6 33.2 21.5 33.1 10.5 17.4 8.4 22.8 16.8 25.9 60.6 39.0 23.0 20.1 49.5 15.4 10.1 16.3 16.4 48.0 15.9 35.3 60.8 32.6 12.2 25.1 36.6 4.6 21.1 27.5 30.2 20.6 45.2 13.5 7.2 37.2 32.2 33.7 51.1 17.3 143.5 32.3 76.9 42.7 27.8 62.4 6.6 10.4 18.8 35.2 25.5 119.4 85.5 50.5 29.6 12.3 34.2 30.5 CBWD6 CBWD7 ENSG00000215126 "COBW domain containing 6" Q4V339 9 41131306-41199261 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.4;Excitatory neurons: 24.9;Inhibitory neurons: 20.2;Langerhans cells: 30.0;Oligodendrocyte precursor cells: 18.6;Suprabasal keratinocytes: 42.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "LHCN-M2: 17.3;PC-3: 26.8;TIME: 16.6" "HPA042759, HPA042813" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA042759: AB_2678149, HPA042813: AB_2678181" "unprognostic (9.48e-2)" "unprognostic (6.02e-2)" "unprognostic (1.62e-2)" "unprognostic (1.91e-2)" "unprognostic (1.30e-2)" "unprognostic (6.28e-2)" "unprognostic (5.92e-2)" "unprognostic (3.71e-2)" "unprognostic (2.07e-2)" "unprognostic (1.12e-1)" "unprognostic (4.24e-2)" "unprognostic (1.09e-1)" "unprognostic (2.28e-4)" "unprognostic (5.65e-2)" "unprognostic (1.65e-1)" "unprognostic (1.01e-2)" "unprognostic (9.94e-4)" 2.0 5.3 1.8 0.7 1.8 2.2 2.1 1.8 3.4 1.0 2.5 1.9 1.1 1.2 0.2 2.9 0.9 1.5 3.4 1.8 2.1 3.4 7.2 2.0 0.3 1.9 1.9 1.6 3.4 0.1 2.7 0.2 2.2 1.7 0.1 0.9 2.5 1.9 3.6 1.5 1.9 0.3 1.9 2.1 2.2 1.9 2.0 0.1 2.2 0.0 0.5 1.1 1.9 1.8 2.0 0.5 0.9 0.2 0.9 2.4 1.6 11.0 12.4 12.6 0.0 4.3 1.2 2.7 0.5 9.0 0.5 1.8 15.9 0.3 0.4 2.8 10.6 0.7 6.4 2.9 0.1 3.4 1.0 0.2 1.5 8.4 10.1 0.9 9.7 0.8 1.4 1.5 17.3 1.8 5.1 0.7 2.3 4.5 26.8 1.2 10.8 3.6 11.5 0.5 0.7 1.2 2.7 0.8 1.1 2.2 0.9 1.5 16.6 0.2 1.0 0.3 1.2 4.9 0.8 13.5 1.5 1.0 1.2 1.6 4.1 1.7 0.6 5.0 0.9 3.5 2.9 2.3 2.3 1.2 1.8 2.2 0.6 0.4 7.0 2.7 1.3 2.4 1.8 1.8 1.8 3.4 1.8 2.1 1.9 1.9 2.2 1.9 2.0 1.8 2.0 3.2 8.9 5.2 1.3 39.4 0.0 11.0 0.0 0.0 5.1 2.7 0.0 0.0 7.5 5.5 0.0 5.2 1.4 0.0 3.9 4.3 0.0 1.5 0.9 1.4 0.0 0.0 24.9 4.9 5.2 1.4 0.0 1.4 8.8 2.2 0.0 0.0 3.0 0.0 20.2 0.0 8.2 0.0 30.0 0.0 0.0 1.4 14.2 5.6 1.6 0.0 0.0 18.6 8.1 4.4 0.0 0.0 1.4 0.0 0.0 8.8 7.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 42.9 6.3 2.8 1.4 0.0 0.0 CCNYL1 FLJ40432 ENSG00000163249 "Cyclin Y like 1" Q8N7R7 2 207711540-207761839 "Predicted intracellular proteins" Cyclin "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 62.7;Paneth cells: 121.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 83.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046825 Approved Approved "Plasma membrane" Yes No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 83: Testis - Spermatogenesis" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA046825: AB_10963934" "unprognostic (2.59e-2)" "unprognostic (1.23e-1)" "unprognostic (1.03e-2)" "unprognostic (1.20e-3)" "unprognostic (1.78e-1)" "unprognostic (1.59e-1)" "unprognostic (1.31e-3)" "unprognostic (5.48e-2)" "unprognostic (1.65e-1)" "unprognostic (1.41e-2)" "unprognostic (7.12e-3)" "unprognostic (7.99e-2)" "unprognostic (3.92e-2)" "unprognostic (8.08e-2)" "unprognostic (7.91e-2)" "unprognostic (2.37e-2)" "unprognostic (1.96e-3)" 12.8 4.7 3.8 10.6 4.9 9.9 7.1 2.8 5.3 8.2 3.7 15.3 11.7 5.0 5.2 17.8 4.2 7.9 6.1 5.2 5.1 10.9 12.4 11.8 8.6 4.8 4.2 3.4 13.7 4.2 4.5 13.6 5.1 4.8 13.3 9.0 6.9 4.8 7.8 3.9 11.3 8.7 4.2 8.1 11.0 16.2 4.5 6.1 11.4 4.4 9.3 10.4 9.5 6.8 25.7 11.0 14.5 20.4 18.6 21.2 83.3 15.6 25.8 15.7 17.7 51.1 23.7 9.9 14.2 28.6 38.5 17.4 17.7 29.4 15.2 3.7 13.5 13.3 12.8 41.6 18.7 11.9 15.2 10.7 12.0 20.0 20.9 13.8 52.5 11.5 6.8 9.4 21.9 13.6 10.5 11.2 28.1 10.3 12.2 9.4 12.4 8.0 16.2 19.5 3.5 10.8 18.5 8.0 23.5 33.6 7.2 31.5 27.3 17.7 16.6 23.2 10.5 5.6 8.4 13.4 18.5 13.5 15.4 0.7 1.1 0.5 0.3 0.6 0.4 0.3 0.5 0.5 0.5 1.1 0.4 0.8 1.3 0.6 0.5 0.5 0.4 0.3 3.8 4.9 2.8 5.3 5.2 5.1 4.8 4.2 5.1 4.2 4.5 6.8 31.8 3.2 19.1 10.1 14.1 12.2 13.8 7.6 5.7 6.2 10.0 10.0 9.0 2.8 8.5 23.9 10.4 12.6 13.2 62.7 1.9 5.8 13.7 13.6 7.7 17.0 9.6 6.5 34.1 14.7 42.9 11.4 25.0 20.4 5.7 5.8 23.9 12.5 16.2 5.0 11.6 13.1 8.2 17.5 29.9 10.9 2.8 18.7 8.8 7.5 20.8 10.2 7.2 14.6 28.7 13.9 121.3 3.8 7.7 16.1 10.1 12.6 6.3 12.3 0.0 16.0 10.4 23.9 9.5 7.6 10.5 7.7 10.9 4.3 17.0 18.0 CCR3 "CC-CKR-3, CD193, CKR3, CMKBR3" ENSG00000183625 "C-C motif chemokine receptor 3" P51677 3 46163604-46266706 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 2.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 1.2;granulocytes: 1.3;Melanocytes: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 25 "basophil: 3389.4;eosinophil: 2509.9" "Lineage enriched" "Detected in many" 109 "granulocytes: 3389.4" "Cell line enriched" "Detected in some" 10 "RPMI-8226: 29.6" "Not detected" "Not detected" "CAB003795, HPA069514" Uncertain Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "CAB003795: AB_562259, HPA069514: " "unprognostic (1.56e-2)" "unprognostic (6.65e-3)" "unprognostic (1.01e-1)" "unprognostic (3.98e-2)" "unprognostic (1.41e-1)" "unprognostic (3.25e-3)" "unprognostic (3.11e-7)" "unprognostic (4.36e-2)" "unprognostic (3.35e-2)" "unprognostic (3.43e-2)" "unprognostic (4.81e-2)" "unprognostic (3.94e-2)" "unprognostic (3.17e-6)" "unprognostic (1.35e-2)" "unprognostic (1.72e-2)" "unprognostic (2.41e-1)" "unprognostic (9.81e-2)" 0.1 0.0 0.2 1.6 0.3 0.4 0.0 0.1 0.5 0.1 1.7 0.8 1.3 0.0 0.0 0.2 0.1 0.7 0.0 0.1 0.2 0.1 0.1 0.6 0.5 0.4 0.0 0.0 0.3 0.0 0.0 0.7 0.4 0.0 0.7 0.0 0.0 0.1 1.7 0.8 2.6 0.9 0.0 1.5 1.2 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 2.6 0.1 0.8 0.0 0.9 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.4 0.1 0.3 0.1 0.0 0.0 0.3 0.0 29.6 0.0 2.4 0.1 0.0 0.1 0.8 0.0 0.8 0.0 0.7 0.0 0.1 0.2 0.0 0.1 3.0 2.6 0.0 0.0 0.5 0.0 3389.4 1.0 2509.9 0.5 1.5 0.8 1.2 2.6 1.4 1.1 0.7 0.3 0.9 115.8 0.5 1.4 3.5 31.1 7.6 0.2 0.3 0.1 0.5 0.1 0.2 0.4 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.2 0.0 0.0 1.3 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.0 CCR4 "CC-CKR-4, CD194, ChemR13, CKR4, CMKBR4, k5-5" ENSG00000183813 "C-C motif chemokine receptor 4" P51679 3 32951644-32956349 "CD markers, FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 13.0;urinary bladder: 5.4" "Cell type enhanced" "Detected in some" "granulocytes: 2.5;Horizontal cells: 5.0;Plasma cells: 2.1;Spermatogonia: 1.8;T-cells: 7.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 5 "T-reg: 60.9" "Lineage enriched" "Detected in many" 41 "T-cells: 60.9" "Cell line enriched" "Detected in some" 17 "HDLM-2: 206.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA031613 Approved Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA031613: AB_10601096" "unprognostic (4.63e-3)" "unprognostic (8.70e-3)" "unprognostic (2.82e-3)" "unprognostic (2.64e-3)" "unprognostic (1.18e-1)" "unprognostic (4.59e-7)" "unprognostic (3.02e-1)" "unprognostic (5.05e-3)" "unprognostic (1.53e-2)" "unprognostic (1.69e-2)" "unprognostic (1.75e-1)" "unprognostic (2.17e-1)" "unprognostic (9.88e-3)" "unprognostic (2.04e-1)" "unprognostic (5.53e-4)" "unprognostic (1.54e-1)" "unprognostic (1.40e-1)" 0.5 0.2 0.3 8.6 0.3 1.7 0.6 0.8 0.7 0.6 0.2 0.9 0.6 0.4 0.3 1.2 0.2 3.3 0.2 0.4 0.4 0.3 0.6 1.7 7.0 0.2 0.1 0.2 0.3 0.2 0.0 0.1 0.4 0.8 1.2 0.1 0.5 0.1 2.0 2.1 1.5 0.6 0.0 3.2 1.4 0.8 0.2 13.0 0.3 0.1 8.0 5.4 0.2 0.7 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.3 0.4 0.2 0.1 0.0 0.0 0.3 0.0 0.1 0.0 206.5 0.0 12.2 0.7 0.1 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.2 0.0 5.8 3.2 0.8 0.0 0.0 1.8 0.2 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.5 0.0 0.1 0.7 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.3 0.4 0.3 0.2 0.1 0.2 0.2 0.2 0.0 1.4 0.3 0.3 0.4 0.3 0.4 0.3 11.5 3.4 0.1 0.4 0.3 0.3 1.1 0.3 0.3 0.4 60.9 1.7 0.3 0.3 0.8 0.7 0.4 0.4 0.2 0.1 0.4 0.0 0.2 0.7 0.1 0.0 0.6 0.0 0.4 0.4 0.7 0.0 0.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.1 2.5 0.0 0.4 0.1 0.1 5.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.7 0.0 0.0 0.7 0.8 0.0 0.5 0.2 0.0 1.8 0.0 0.1 0.0 7.8 0.0 0.0 0.6 CD163 "M130, MM130, SCARI1" ENSG00000177575 "CD163 molecule" Q86VB7 12 7470811-7503893 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Acute phase, Inflammatory response" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 240.5" "Cell type enriched" "Detected in many" 4 "Kupffer cells: 1756.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "classical monocyte: 76.1;myeloid DC: 65.2" "Group enriched" "Detected in many" 40 "dendritic cells: 65.2;monocytes: 76.1" "Cell line enhanced" "Detected in some" "GAMG: 1.8;HSkMC: 1.7" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "CAB002432, HPA046404, HPA051974" Enhanced Supported "Plasma membrane" "Secreted to blood" NA NA 903000000 1600000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB002432: AB_563510, HPA046404: AB_2679655, HPA051974: AB_2681678" "unprognostic (1.13e-1)" "unprognostic (2.13e-1)" "unprognostic (5.02e-3)" "unprognostic (2.72e-1)" "unprognostic (6.17e-3)" "unprognostic (2.09e-1)" "unprognostic (1.02e-1)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "prognostic unfavorable (7.27e-4)" "unprognostic (1.04e-1)" "unprognostic (6.50e-2)" "unprognostic (1.84e-2)" "unprognostic (8.77e-2)" "unprognostic (4.95e-2)" "unprognostic (1.61e-1)" "unprognostic (1.20e-2)" 171.8 85.6 6.1 152.5 7.0 17.6 50.8 5.2 18.4 25.6 21.5 48.7 12.4 27.3 3.6 16.4 68.1 43.5 52.7 4.9 7.9 27.3 89.7 131.7 54.4 15.8 10.9 23.1 21.4 8.8 11.4 109.4 18.0 15.5 21.6 4.3 25.9 7.2 11.4 15.3 52.9 130.4 7.2 240.5 35.6 9.7 55.9 18.7 17.2 17.6 7.2 68.5 16.3 10.3 0.0 0.0 0.0 0.0 0.6 0.3 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 76.1 0.5 0.1 6.4 0.0 0.0 0.0 0.1 65.2 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.1 20.1 6.1 7.0 5.2 18.4 4.9 7.9 15.8 10.9 18.0 7.2 55.9 10.3 2.7 3.2 8.3 0.0 3.8 1.5 0.2 0.0 0.0 0.1 0.1 0.3 4.6 7.2 5.0 0.0 2.1 1.5 0.5 0.0 0.0 0.0 4.3 0.0 0.1 13.9 0.0 3.6 0.4 0.0 1.9 3.0 0.5 0.0 5.1 0.1 17.9 13.9 269.9 0.0 0.5 0.0 0.0 1756.1 30.9 6.4 5.0 387.9 0.0 2.8 41.1 0.9 1.0 0.0 0.0 0.0 0.0 1.2 1.0 0.1 0.0 0.2 1.6 0.2 118.3 1.7 4.0 3.9 2.6 0.5 1.0 3.0 1.3 0.0 0.0 0.1 CD200R1 "CD200R, HCRTR2, MOX2R, OX2R" ENSG00000163606 "CD200 receptor 1" Q8TD46 3 112921205-112975103 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 7.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 14.8;granulocytes: 15.2;Hepatic stellate cells: 14.6;Hofbauer cells: 31.8;Langerhans cells: 19.9;T-cells: 12.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enriched" "Detected in many" 4 "basophil: 234.9" "Lineage enriched" "Detected in all" 10 "granulocytes: 234.9" "Cell line enriched" "Detected in some" 8 "HEL: 25.5" HPA068512 Supported "Plasma membrane" "Intracellular and membrane" NA NA 2000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 36: HEL - Hemostasis" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA068512: AB_2732784" "unprognostic (1.49e-2)" "unprognostic (1.06e-2)" "unprognostic (2.55e-1)" "unprognostic (1.97e-2)" "unprognostic (1.53e-1)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-3)" "unprognostic (8.30e-2)" "unprognostic (1.85e-1)" "unprognostic (7.98e-2)" "unprognostic (2.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.77e-1)" "unprognostic (7.84e-3)" "unprognostic (1.25e-1)" "unprognostic (5.12e-3)" 1.7 1.2 0.3 3.0 0.4 1.7 1.4 0.2 0.6 0.7 0.7 1.5 1.6 0.7 0.3 3.8 0.5 1.9 0.6 0.4 0.3 0.5 2.4 1.9 4.4 0.3 0.2 0.3 0.5 0.5 0.2 5.3 0.3 0.6 2.3 0.1 0.6 0.7 0.1 2.6 2.0 1.1 0.2 7.9 1.5 0.7 0.2 3.4 0.5 0.9 4.6 1.9 0.5 0.2 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.6 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.3 25.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.0 1.2 0.0 234.9 2.9 53.6 4.0 1.3 7.0 9.9 13.8 7.9 22.9 5.6 13.4 6.1 0.8 2.5 0.4 0.5 4.3 5.2 0.3 0.4 0.2 0.6 0.4 0.3 0.3 0.2 0.3 0.2 0.2 0.2 0.2 0.0 1.1 1.6 4.4 1.9 0.1 0.0 14.8 0.0 0.2 0.3 0.3 0.0 0.1 0.0 0.0 0.3 1.9 0.0 0.0 0.0 0.1 1.0 0.1 0.5 0.0 4.0 5.7 0.0 0.2 0.9 0.0 0.1 15.2 0.0 14.6 0.1 31.8 0.0 2.2 0.0 0.0 6.7 19.9 0.0 0.0 9.1 5.4 5.6 5.2 0.0 0.0 1.0 0.7 0.1 0.0 0.0 2.7 0.1 0.0 0.1 1.2 0.0 0.0 0.3 0.4 0.8 0.3 5.8 0.9 0.7 12.4 0.0 0.0 0.2 CD300LB "CLM7, TREM5" ENSG00000178789 "CD300 molecule like family member b" A8K4G0 17 74521174-74531475 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" Immunity Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 7.8;brain: 16.3;lymphoid tissue: 8.2" "Group enriched" "Detected in some" 4 "dendritic cells: 7.1;Hofbauer cells: 6.2;Kupffer cells: 8.7;Langerhans cells: 6.5;Macrophages: 16.6;monocytes: 13.9" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 5 "cerebral cortex: 16.3" "Immune cell enhanced" "Detected in many" "eosinophil: 75.9" "Group enriched" "Detected in many" 53 "dendritic cells: 25.0;granulocytes: 75.9;monocytes: 31.7" "Group enriched" "Detected in some" 6 "HL-60: 1.7;NB-4: 2.4;THP-1: 1.9;U-937: 1.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA060449 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 24: NB-4 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA060449: " "unprognostic (1.39e-1)" "unprognostic (2.44e-2)" "unprognostic (1.37e-1)" "unprognostic (4.39e-2)" "unprognostic (3.59e-2)" "unprognostic (1.15e-1)" "unprognostic (6.41e-2)" "unprognostic (7.69e-2)" "unprognostic (2.05e-1)" "unprognostic (2.95e-2)" "unprognostic (6.24e-2)" "unprognostic (3.32e-1)" "unprognostic (2.49e-4)" "unprognostic (2.92e-2)" "unprognostic (1.79e-2)" "unprognostic (7.08e-2)" "unprognostic (4.01e-2)" 1.7 0.4 0.1 8.2 0.2 7.8 0.7 0.1 16.3 0.4 0.6 0.7 0.7 0.3 0.0 0.3 0.3 2.1 0.2 0.1 0.2 0.2 0.8 1.7 0.8 0.3 0.3 0.1 0.9 0.1 0.2 0.9 3.1 0.4 0.9 0.0 0.3 0.1 0.3 0.1 1.6 1.8 0.2 3.7 0.6 0.3 1.3 0.6 0.2 0.1 0.9 2.5 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 1.1 0.0 1.5 31.7 75.9 0.1 13.6 0.3 0.0 0.0 0.0 25.0 0.0 0.0 0.2 33.3 0.8 1.9 15.6 0.0 11.8 0.1 0.2 0.1 16.3 0.1 0.2 0.3 0.3 3.1 0.2 1.3 0.4 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.0 0.6 0.0 0.0 0.0 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.4 0.2 6.2 0.0 0.0 0.0 0.0 8.7 6.5 0.2 0.0 16.6 0.0 0.0 13.9 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 CD38 ENSG00000004468 "CD38 molecule" P28907 4 15778275-15853232 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Receptor, Transferase" "Cancer-related genes, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 63.3" "Cell type enriched" "Detected in many" 4 "Plasma cells: 378.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 18.3" "Group enriched" "Detected in all" 5 "B-cells: 9.9;dendritic cells: 5.8;NK-cells: 18.3" "Cell line enhanced" "Detected in some" "Daudi: 128.0;Karpas-707: 34.7;MOLT-4: 32.6;REH: 26.0;RPMI-8226: 20.9;U-266/70: 26.9;U-698: 24.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002493, HPA022132, CAB025255, HPA052381" Enhanced Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB002493: AB_563556, CAB025255: , HPA022132: AB_1846300, HPA052381: AB_2681807" "unprognostic (1.27e-2)" "unprognostic (8.06e-3)" "unprognostic (1.06e-2)" "prognostic favorable (9.68e-4)" "unprognostic (1.13e-1)" "unprognostic (1.82e-3)" "unprognostic (2.74e-1)" "unprognostic (8.51e-2)" "unprognostic (5.87e-2)" "unprognostic (6.15e-6)" "unprognostic (5.23e-1)" "unprognostic (4.34e-1)" "unprognostic (6.63e-6)" "unprognostic (1.79e-1)" "unprognostic (5.74e-2)" "unprognostic (2.12e-2)" "unprognostic (2.13e-1)" 3.1 2.4 2.5 13.1 3.8 13.6 2.0 2.7 2.5 0.7 0.9 4.5 5.8 0.9 1.2 1.1 3.0 1.9 3.8 3.5 6.6 0.8 3.3 6.3 23.4 3.3 5.5 0.7 0.3 0.1 1.8 0.5 3.4 13.2 3.5 0.2 2.6 19.7 21.4 0.3 5.3 1.4 2.8 17.0 3.0 1.0 3.9 63.3 2.0 3.4 18.0 6.8 0.5 4.6 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 128.0 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 17.0 0.2 34.7 0.0 0.0 32.6 7.9 0.2 0.0 0.0 26.0 0.1 20.9 0.0 0.0 0.2 1.5 0.0 0.2 0.5 0.3 0.1 5.7 0.5 0.0 0.1 0.1 0.0 26.9 0.2 24.3 0.4 6.2 0.3 0.1 1.9 0.1 1.2 2.4 0.3 9.9 1.5 1.2 4.7 7.7 2.4 1.9 1.4 18.3 1.9 5.8 2.4 4.4 2.5 3.8 2.7 2.5 3.5 6.6 3.3 5.5 3.4 2.8 3.9 4.6 0.8 3.2 15.1 86.5 59.7 0.0 0.4 0.6 0.6 0.1 0.1 0.0 1.0 0.0 11.6 0.0 10.4 0.2 33.8 0.2 0.0 0.0 2.5 4.0 1.4 2.7 0.0 78.6 0.4 0.0 0.2 2.7 2.0 0.3 38.2 0.8 2.9 4.3 4.4 0.0 0.4 1.3 0.0 44.3 0.8 0.7 0.0 17.7 7.2 5.6 3.1 0.0 79.3 1.0 1.8 0.0 0.3 0.0 378.4 8.1 0.2 0.1 42.5 0.1 13.1 1.5 7.6 2.9 1.7 1.6 0.0 0.5 26.5 0.0 1.6 0.2 CD4 ENSG00000010610 "CD4 molecule" P01730 12 6786858-6820799 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 152.9;lymphoid tissue: 219.3;parathyroid gland: 173.8" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 278.8;Hofbauer cells: 139.3;Kupffer cells: 247.1;Langerhans cells: 80.1;Macrophages: 109.0;monocytes: 104.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 18 "classical monocyte: 247.3;intermediate monocyte: 241.4;memory CD4 T-cell: 153.4;myeloid DC: 166.3;naive CD4 T-cell: 128.1;non-classical monocyte: 204.2;plasmacytoid DC: 263.8;T-reg: 154.5" "Group enriched" "Detected in many" 20 "dendritic cells: 263.8;monocytes: 247.3;T-cells: 154.5" "Group enriched" "Detected in some" 6 "HEL: 103.2;HL-60: 42.1;NB-4: 60.0;THP-1: 116.2;U-937: 109.7" "Region enriched" "Detected in many" 14 "basal ganglia: 46.2" "Low region specificity" "Detected in many" "CAB000011, HPA004252, HPA004472, CAB068180" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB000011: AB_442062, CAB068180: AB_2665653, HPA004252: AB_1078466, HPA004472: AB_1078465" "unprognostic (1.39e-2)" "unprognostic (1.12e-2)" "unprognostic (2.75e-2)" "prognostic favorable (2.16e-4)" "unprognostic (7.76e-2)" "unprognostic (4.82e-3)" "unprognostic (3.70e-2)" "unprognostic (2.74e-2)" "unprognostic (7.04e-2)" "unprognostic (2.40e-1)" "unprognostic (1.13e-1)" "unprognostic (1.92e-1)" "prognostic unfavorable (7.45e-4)" "unprognostic (1.06e-1)" "unprognostic (4.65e-3)" "unprognostic (9.08e-3)" "unprognostic (2.95e-1)" 45.5 16.2 15.0 82.1 15.4 26.5 14.7 15.5 17.4 20.4 15.8 26.0 18.7 7.9 7.0 15.1 21.3 35.3 10.0 15.1 16.7 10.1 152.9 72.1 119.0 22.9 20.2 8.6 7.6 173.8 6.1 47.4 21.0 7.3 31.0 10.5 8.5 10.3 2.9 12.6 27.4 26.5 19.6 164.4 21.0 7.5 19.6 219.3 8.8 5.7 75.7 41.0 5.8 25.7 0.0 0.0 3.6 0.1 0.1 0.2 0.3 0.1 2.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 5.2 0.0 103.2 0.0 0.6 10.5 42.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 15.4 60.0 1.0 0.0 0.0 0.0 0.2 12.8 0.1 0.0 0.2 0.2 0.0 0.0 0.1 0.7 0.1 116.2 0.1 0.0 0.1 0.2 0.1 0.0 0.1 0.2 0.1 109.7 0.0 0.8 247.3 1.9 2.0 241.4 6.3 0.5 153.4 0.8 166.3 0.5 128.1 0.7 11.1 2.0 204.2 263.8 154.5 240.6 15.0 15.4 15.5 17.4 15.1 16.7 22.9 20.2 21.0 19.6 19.6 25.7 4.5 0.0 5.2 1.6 5.2 3.4 0.3 0.4 0.0 1.5 2.9 5.8 2.1 8.6 2.1 3.7 0.0 0.9 61.9 0.0 5.9 0.0 0.1 3.5 8.7 9.6 0.0 7.8 0.9 0.4 1.2 3.7 0.0 0.4 7.6 0.4 278.8 34.3 139.3 5.0 0.7 0.0 0.0 247.1 80.1 0.5 16.8 109.0 5.4 29.0 104.5 22.0 6.2 0.5 0.2 0.0 0.0 15.1 2.5 0.2 0.0 3.3 20.3 0.2 13.1 0.7 13.5 0.0 0.2 0.4 2.3 1.2 34.0 0.0 0.0 0.4 CD46 "MCP, MGC26544, MIC10, TLX, TRA2.10" ENSG00000117335 "CD46 molecule" P15529 1 207752054-207795513 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Complement pathway, Fertilization, Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Cancer-related genes, Disease variant, Hemolytic uremic syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 296.7;eosinophil: 382.4;neutrophil: 401.8" "Lineage enriched" "Detected in all" 5 "granulocytes: 401.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "CAB010401, HPA016903" Enhanced Approved "Plasma membrane" NA NA 1000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "CAB010401: AB_2291289, HPA016903: AB_1846309" "unprognostic (1.42e-2)" "prognostic unfavorable (8.54e-5)" "unprognostic (3.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.91e-2)" "unprognostic (1.82e-1)" "unprognostic (1.25e-1)" "unprognostic (2.74e-1)" "unprognostic (8.79e-2)" "unprognostic (2.50e-1)" "unprognostic (6.78e-3)" "prognostic favorable (2.38e-4)" "unprognostic (1.76e-1)" "unprognostic (8.23e-2)" "unprognostic (1.49e-2)" 98.6 237.4 30.0 64.0 35.0 80.5 128.4 33.5 39.5 74.0 61.4 103.1 124.6 62.1 77.1 102.2 110.0 73.8 64.9 30.2 34.4 173.2 133.9 129.1 58.2 37.4 33.6 61.2 112.5 310.6 41.8 221.5 38.1 167.4 103.2 72.6 166.9 107.4 47.4 47.7 98.6 67.1 34.8 79.6 117.4 40.5 36.3 44.4 86.8 58.1 66.6 97.2 68.2 41.5 130.0 71.7 66.1 30.8 202.9 199.2 99.9 95.0 137.3 61.3 82.5 71.3 335.4 19.8 94.3 95.3 84.5 170.7 50.0 130.5 93.0 99.9 70.9 42.9 73.8 128.6 128.8 94.8 142.8 172.9 189.6 92.9 72.5 144.4 174.2 76.8 91.8 83.4 95.7 61.3 45.4 82.8 75.6 76.9 70.9 30.2 104.7 123.0 251.4 252.6 66.5 45.4 120.5 266.8 160.1 130.8 210.2 79.8 150.9 65.6 57.7 139.2 109.9 111.2 144.3 60.1 95.8 61.2 63.0 296.7 79.8 382.4 50.1 82.4 68.9 43.5 63.3 55.8 47.3 34.1 71.1 60.5 401.8 46.9 87.5 24.9 60.5 102.4 30.0 35.0 33.5 39.5 30.2 34.4 37.4 33.6 38.1 34.8 36.3 41.5 186.0 201.9 241.1 59.7 60.3 52.9 89.3 87.2 108.1 63.0 144.3 85.7 61.4 75.8 177.8 145.3 66.7 247.3 94.0 105.2 15.6 77.4 227.7 206.1 67.0 106.7 72.8 46.9 61.0 79.9 76.2 70.5 97.9 231.3 114.5 78.1 77.8 120.9 59.9 40.4 73.6 91.1 87.5 78.9 63.1 36.9 47.2 91.6 62.2 82.4 88.7 25.3 39.1 112.1 153.9 72.8 117.7 44.0 76.0 144.5 92.6 54.4 208.8 87.3 52.6 69.7 89.3 17.1 20.2 104.5 45.9 343.7 89.9 99.4 115.9 165.7 CD8A CD8 ENSG00000153563 "CD8a molecule" P01732 2 86784610-86808396 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 16 "lymphoid tissue: 369.0" "Group enriched" "Detected in many" 4 "dendritic cells: 111.7;T-cells: 242.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 14 "MAIT T-cell: 234.4;memory CD8 T-cell: 523.0;naive CD8 T-cell: 476.8" "Lineage enriched" "Detected in many" 19 "T-cells: 523.0" "Cell line enhanced" "Detected in some" "JURKAT: 4.0;MOLT-4: 15.2;RPMI-8226: 3.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB000012, HPA037756, CAB075722" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 490000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 63: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB000012: AB_2075537, CAB075722: AB_2665709, HPA037756: AB_2675648" "unprognostic (1.29e-3)" "prognostic favorable (4.54e-4)" "unprognostic (9.26e-3)" "prognostic favorable (6.15e-6)" "unprognostic (7.28e-2)" "unprognostic (2.79e-3)" "unprognostic (1.03e-2)" "unprognostic (2.00e-2)" "unprognostic (1.35e-2)" "unprognostic (4.50e-3)" "unprognostic (1.09e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.91e-5)" "unprognostic (1.36e-1)" "unprognostic (1.48e-1)" "unprognostic (6.74e-2)" "unprognostic (1.56e-2)" 5.3 4.6 2.1 21.2 2.8 22.5 4.7 1.9 3.0 3.8 1.4 4.9 11.8 3.0 3.6 4.4 4.0 9.8 2.3 2.1 2.1 1.8 7.4 10.5 45.0 2.8 2.1 2.5 2.6 1.1 1.5 0.6 2.5 3.4 5.9 0.2 8.3 1.9 0.8 1.3 20.7 2.4 2.2 117.1 16.4 1.0 2.3 369.0 4.4 0.4 21.4 9.1 4.0 2.1 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.4 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 4.0 0.0 0.2 0.0 0.6 15.2 0.9 0.5 0.1 0.2 0.1 0.7 3.3 0.0 0.3 0.7 1.9 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.5 0.1 0.0 0.1 0.2 0.7 0.0 0.0 0.0 1.4 0.8 0.3 30.0 0.3 234.4 0.6 2.3 523.0 0.4 0.6 2.2 476.8 4.3 27.9 0.9 1.2 0.8 152.4 2.1 2.8 1.9 3.0 2.1 2.1 2.8 2.1 2.5 2.2 2.3 2.1 2.2 0.0 4.6 0.0 5.7 2.0 0.2 0.0 0.0 0.3 1.5 1.5 3.4 1.5 0.6 0.0 0.0 0.0 111.7 0.2 0.0 0.2 0.3 0.5 0.3 1.3 0.0 7.8 4.2 0.0 0.0 2.6 8.2 0.4 2.5 0.0 6.4 2.3 0.1 0.0 3.1 0.3 0.0 1.9 11.5 0.2 0.0 6.6 0.0 1.0 5.9 0.1 38.1 0.0 0.2 0.0 0.0 0.0 30.8 0.2 0.0 0.4 1.5 0.4 0.0 1.1 1.4 0.4 0.4 1.1 1.8 0.1 242.4 0.0 0.6 0.1 CD8B CD8B1 ENSG00000172116 "CD8b molecule" P10966 2 86815339-86861924 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "lymphoid tissue: 459.6" "Group enriched" "Detected in many" 8 "dendritic cells: 53.2;T-cells: 162.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 10 "memory CD8 T-cell: 601.8;naive CD8 T-cell: 1053.9" "Lineage enriched" "Detected in all" 25 "T-cells: 1053.9" "Cell line enriched" "Detected in some" 60 "RPMI-8226: 1113.4" "CAB004353, HPA029164" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 63: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB004353: AB_627211, HPA029164: AB_2672936" "unprognostic (1.83e-3)" "unprognostic (1.98e-3)" "unprognostic (2.22e-2)" "prognostic favorable (7.88e-7)" "unprognostic (6.23e-2)" "unprognostic (7.05e-3)" "unprognostic (1.11e-2)" "unprognostic (2.59e-2)" "unprognostic (5.50e-3)" "unprognostic (5.91e-2)" "unprognostic (9.25e-2)" "unprognostic (4.60e-1)" "prognostic unfavorable (7.11e-6)" "unprognostic (7.84e-2)" "unprognostic (3.00e-1)" "unprognostic (1.86e-2)" "unprognostic (4.33e-2)" 1.9 1.9 0.4 10.6 0.3 8.3 2.9 1.1 0.6 33.4 0.1 2.1 5.0 1.2 1.1 1.6 1.5 4.3 1.0 0.1 1.2 1.0 1.6 4.2 25.9 5.0 2.1 0.9 0.9 4.6 8.8 0.3 4.8 1.7 3.0 0.0 2.4 1.0 0.6 1.4 15.1 1.1 0.7 15.6 5.1 0.4 2.4 459.6 2.0 0.4 15.1 3.4 1.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 18.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 7.0 0.0 0.0 0.0 0.1 0.2 0.0 1113.4 0.0 0.0 0.3 0.1 0.0 0.5 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 6.6 0.0 0.0 0.0 42.0 1.0 0.8 15.7 1.1 79.3 0.7 1.9 601.8 0.6 1.2 4.6 1053.9 6.1 1.1 1.7 1.0 2.2 427.6 0.4 0.3 1.1 0.6 0.1 1.2 5.0 2.1 4.8 0.7 2.4 0.5 1.3 6.4 5.5 0.0 4.4 4.0 2.2 0.0 0.6 0.0 2.2 2.8 1.0 1.5 0.0 0.0 0.0 0.1 53.2 0.1 0.0 0.1 0.5 0.2 0.5 0.7 0.0 1.7 0.4 0.0 0.0 2.0 7.1 0.2 0.0 0.0 0.7 0.5 0.1 0.0 0.5 4.6 0.0 4.0 4.3 0.5 0.0 4.1 5.4 5.6 7.5 0.0 10.3 0.0 0.1 0.0 0.1 0.0 10.8 0.7 12.4 0.2 0.0 0.0 0.0 2.0 1.2 0.2 0.1 0.5 2.8 0.0 162.9 0.0 7.5 0.3 CD9 "BA2, MIC3, MRP-1, P24, TSPAN29" ENSG00000010278 "CD9 molecule" P21926 12 6199715-6238271 "Cancer-related genes, CD markers, Plasma proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Fertilization" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 2822.0;Ionocytes: 4461.6;Urothelial cells: 2594.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 25 "basophil: 1957.3;eosinophil: 1156.4" "Lineage enriched" "Detected in all" 32 "granulocytes: 1957.3" "Cell line enhanced" "Detected in many" "CAPAN-2: 1521.6;RT4: 1126.8;TIME: 2266.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB002490 Supported Supported "Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 2: Granulocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB002490: AB_563643" "unprognostic (1.38e-1)" "unprognostic (6.36e-3)" "unprognostic (8.27e-3)" "unprognostic (6.98e-3)" "unprognostic (3.89e-1)" "unprognostic (2.81e-1)" "unprognostic (1.32e-1)" "unprognostic (2.08e-2)" "unprognostic (2.90e-1)" "unprognostic (2.60e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (2.30e-1)" "prognostic favorable (6.49e-5)" "unprognostic (6.10e-2)" "unprognostic (1.77e-1)" "prognostic favorable (8.93e-5)" "unprognostic (9.26e-2)" 204.4 287.8 116.9 96.5 162.9 17.3 298.9 139.8 193.3 399.5 157.3 496.9 127.2 242.4 270.9 1000.2 242.3 102.4 267.5 124.3 132.3 294.2 79.4 403.0 37.4 165.8 141.0 69.0 93.4 881.8 98.1 85.4 160.2 488.5 466.2 32.6 614.5 456.4 74.4 455.3 211.2 197.0 139.2 69.5 178.2 26.4 146.5 66.1 338.0 116.6 289.4 373.1 566.4 207.1 417.6 173.7 3.5 108.7 167.7 170.8 150.1 241.1 477.8 80.8 121.9 128.5 1521.6 1.4 59.2 51.4 239.0 885.6 92.7 475.5 62.7 21.5 63.1 2.0 117.1 26.6 71.3 1.1 497.0 0.6 347.0 147.3 126.0 225.3 976.3 28.9 19.3 1.7 51.5 578.6 1.8 45.4 136.0 504.3 175.7 4.1 290.1 529.7 802.1 1126.8 0.5 34.0 240.9 195.8 215.8 789.0 91.1 42.1 2266.0 8.6 214.6 8.8 29.5 1.7 1.3 63.2 137.2 1.0 221.7 1957.3 61.1 1156.4 1.3 23.6 2.2 5.5 1.4 1.6 10.2 20.5 4.2 11.5 30.9 2.6 0.6 3.7 0.4 71.7 116.9 162.9 139.8 193.3 124.3 132.3 165.8 141.0 160.2 139.2 146.5 207.1 250.0 794.9 403.1 35.6 27.8 1037.8 1864.4 2822.0 804.1 4.9 433.5 379.5 20.9 84.4 1403.7 1075.9 0.0 21.5 8.7 929.9 137.0 599.1 3.0 457.8 66.8 496.5 172.9 10.5 0.4 178.2 271.0 356.9 60.6 722.6 653.4 42.3 522.6 43.1 618.0 0.0 0.6 744.8 4461.6 35.2 685.3 13.1 32.0 253.4 940.9 11.2 151.7 375.1 2.1 56.3 169.5 352.9 896.4 70.7 59.3 1576.4 330.0 21.7 1409.8 14.7 664.0 322.6 397.5 7.3 74.1 1214.3 1279.8 54.0 77.8 838.5 761.1 2594.9 CD99L2 "CD99B, MIC2L1" ENSG00000102181 "CD99 molecule like 2" Q8TCZ2 X 150766336-150898816 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 179.1" "Cell type enhanced" "Detected in many" "Excitatory neurons: 49.1;Horizontal cells: 52.2;Inhibitory neurons: 57.2;Oligodendrocytes: 60.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038782, HPA038783, HPA061400" Enhanced Supported "Plasma membrane" NA NA 1200000 "Cluster 27: Non-specific - Gene expression" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA038782: AB_10795139, HPA038783: AB_10794734, HPA061400: AB_2732660" "unprognostic (2.10e-2)" "unprognostic (2.62e-3)" "unprognostic (3.12e-3)" "unprognostic (6.03e-3)" "unprognostic (1.22e-1)" "unprognostic (2.66e-1)" "unprognostic (5.56e-2)" "prognostic favorable (4.96e-4)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "prognostic favorable (2.74e-5)" "unprognostic (5.50e-2)" "unprognostic (5.13e-2)" "unprognostic (1.35e-1)" "unprognostic (6.74e-2)" "unprognostic (9.23e-2)" "prognostic unfavorable (8.74e-4)" 46.1 28.1 68.5 14.8 69.5 7.3 29.7 71.0 99.6 33.4 26.8 40.1 10.0 39.9 24.5 14.5 30.5 19.2 61.6 69.9 80.4 24.9 47.3 25.2 13.2 104.7 77.9 38.9 18.7 14.6 23.8 21.5 107.2 25.8 10.6 43.4 14.8 32.6 179.1 13.4 19.2 32.4 71.5 26.9 21.8 11.2 91.6 14.5 16.8 99.2 10.7 29.4 21.0 80.2 8.1 79.8 29.5 36.9 153.3 95.2 8.7 65.2 76.1 32.3 46.3 5.5 10.2 29.3 154.0 114.6 24.2 13.0 40.4 44.4 26.6 68.5 31.9 12.7 17.8 8.2 41.2 21.4 23.3 90.3 14.5 24.0 45.4 50.3 38.6 22.4 8.9 74.9 41.1 17.3 18.9 31.1 12.4 6.9 42.7 18.8 24.2 40.5 31.7 5.4 38.9 19.9 25.8 21.9 29.6 21.6 6.2 36.6 45.8 47.5 14.4 62.2 48.0 62.6 112.3 28.3 59.6 42.3 36.4 7.3 8.6 5.9 6.2 7.6 5.4 4.5 5.8 6.3 8.1 4.8 5.5 6.0 2.1 7.2 12.5 5.8 4.4 7.0 68.5 69.5 71.0 99.6 69.9 80.4 104.7 77.9 107.2 71.5 91.6 80.2 14.1 16.0 7.8 21.5 8.2 3.1 2.3 3.6 4.6 26.8 3.7 3.2 42.8 11.5 6.4 12.9 18.8 10.1 7.4 2.0 5.9 4.4 0.3 5.6 10.1 13.8 8.4 6.5 49.1 5.3 3.9 15.9 7.1 3.6 7.6 12.6 17.2 26.6 10.2 52.2 57.2 2.9 8.2 16.4 6.8 2.8 20.8 8.6 10.6 23.4 8.1 18.2 2.1 21.6 60.7 3.6 3.1 30.1 12.5 3.4 5.3 11.3 5.0 18.7 0.0 15.9 12.0 2.8 4.9 3.3 1.3 13.5 6.4 11.8 3.3 1.3 CDH13 CDHH ENSG00000140945 "Cadherin 13" P55290 16 82626965-83800640 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 57.1;skeletal muscle: 68.6;tongue: 57.7" "Group enriched" "Detected in many" 4 "Excitatory neurons: 328.8;Inhibitory neurons: 867.0;Oligodendrocyte precursor cells: 335.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 4.3" "Group enriched" "Detected in many" 6 "granulocytes: 2.2;monocytes: 4.3" "Cell line enhanced" "Detected in many" "LHCN-M2: 222.2;U-138 MG: 279.2;U-87 MG: 244.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001380, CAB025863" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 240000000 "Cluster 7: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB025863: , HPA001380: AB_1078371" "unprognostic (2.50e-2)" "unprognostic (2.75e-2)" "unprognostic (5.61e-2)" "unprognostic (4.06e-1)" "unprognostic (4.88e-2)" "unprognostic (3.30e-3)" "unprognostic (3.01e-1)" "unprognostic (5.76e-2)" "unprognostic (3.49e-2)" "unprognostic (3.34e-1)" "unprognostic (2.21e-1)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.73e-6)" "unprognostic (5.16e-3)" "unprognostic (2.01e-1)" "unprognostic (1.25e-1)" "unprognostic (1.21e-1)" 20.3 2.8 18.7 3.8 21.5 0.6 10.0 0.0 14.3 42.5 0.0 5.0 1.5 47.2 3.3 9.5 7.6 5.0 57.1 10.5 3.3 5.0 1.8 16.1 1.4 1.5 6.5 3.1 0.6 2.4 0.5 6.0 0.6 3.5 6.2 1.5 4.9 7.2 68.6 21.1 2.3 29.9 6.3 2.1 1.7 1.8 22.9 1.8 5.8 57.7 1.9 7.1 19.4 3.2 10.2 0.0 3.6 0.5 63.2 60.6 0.1 47.1 51.9 53.6 23.1 0.1 0.4 0.1 8.5 138.5 26.0 89.1 1.0 70.7 79.8 0.0 0.2 0.1 31.4 0.1 36.4 0.0 0.4 7.9 59.9 107.8 130.4 83.9 26.7 0.0 0.2 0.5 222.2 0.5 0.1 0.2 10.6 0.0 19.4 0.0 57.7 0.0 46.2 0.4 0.1 0.1 84.4 0.3 0.1 103.5 0.8 0.1 43.1 279.2 22.7 1.6 43.0 0.2 0.1 0.2 244.0 0.2 70.1 2.2 0.5 1.4 0.0 2.1 0.0 0.5 0.0 0.0 0.5 0.5 0.0 0.0 1.1 0.0 4.3 0.3 0.0 0.2 18.7 21.5 0.0 14.3 10.5 3.3 1.5 6.5 0.6 6.3 22.9 3.2 125.4 0.0 0.5 11.1 0.3 70.7 28.7 32.3 25.0 3.0 1.0 5.8 86.9 0.0 2.6 3.7 0.0 0.1 0.9 2.1 7.9 0.4 44.5 1.0 27.1 49.2 1.8 0.0 328.8 0.0 0.2 9.7 0.0 0.7 0.0 0.0 29.6 0.3 0.6 5.0 867.0 1.6 0.0 1.9 13.3 43.3 0.3 1.4 8.8 17.8 0.0 0.4 0.0 335.8 65.0 0.1 1.4 0.0 0.0 36.7 0.0 1.3 0.8 0.4 0.0 51.0 22.7 2.9 0.6 3.3 18.8 0.1 1.2 0.7 0.1 6.4 CDH4 ENSG00000179242 "Cadherin 4" P55283 20 61252261-61940617 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 11.0;lymphoid tissue: 3.7;ovary: 6.3;skeletal muscle: 3.8" "Cell type enhanced" "Detected in some" "Astrocytes: 157.0;Excitatory neurons: 54.4;Inhibitory neurons: 70.0;Oligodendrocyte precursor cells: 108.0;Skeletal myocytes: 28.7" "Group enriched" "Detected in many" 6 "glioma: 6.9;renal cancer: 3.4;thyroid cancer: 2.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 10.8;hTERT-HME1: 14.1;U-2 OS: 19.4;U-251 MG: 35.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015613 Supported "Plasma membrane" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 65: Brain - Ion transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA015613: AB_2732414" "unprognostic (1.64e-1)" "unprognostic (1.19e-2)" "unprognostic (3.39e-4)" "unprognostic (2.16e-1)" "unprognostic (2.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.64e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-1)" "unprognostic (1.27e-1)" "unprognostic (1.85e-1)" "unprognostic (6.72e-2)" "unprognostic (6.08e-3)" "unprognostic (1.75e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (6.78e-2)" 0.1 1.3 7.3 0.0 4.3 0.1 0.2 0.0 3.4 0.6 0.0 0.3 0.0 0.2 0.0 0.2 0.6 0.1 0.2 3.0 5.0 0.3 0.2 0.3 0.0 1.3 3.0 6.3 0.5 0.1 0.5 0.0 0.4 0.3 0.0 0.7 0.3 0.8 3.8 0.7 0.2 0.0 0.0 3.7 0.2 0.9 11.0 0.2 0.3 0.0 0.0 0.2 0.2 1.1 0.1 1.2 10.8 0.0 0.2 0.7 0.2 3.1 0.0 5.6 0.6 0.3 0.0 0.0 0.3 3.7 3.6 4.1 0.0 6.2 2.2 0.3 0.0 0.0 0.1 0.1 7.1 0.0 0.1 1.1 1.4 1.1 14.1 3.0 1.2 0.4 0.0 0.1 2.1 0.4 0.1 0.1 1.3 0.0 0.1 0.0 0.0 1.6 3.2 0.0 1.0 2.7 0.0 0.1 0.1 1.6 0.0 0.0 0.0 0.0 19.4 0.1 35.2 6.3 0.1 0.1 6.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 7.3 4.3 0.0 3.4 3.0 5.0 1.3 3.0 0.4 0.0 11.0 1.1 0.0 3.2 0.0 157.0 0.0 0.3 0.4 0.0 0.0 1.8 0.4 0.9 1.6 0.0 0.7 0.0 2.1 0.0 0.1 0.1 0.0 1.3 0.9 0.1 0.3 0.2 0.0 0.0 54.4 0.0 0.0 1.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 16.8 70.0 0.0 0.0 0.0 0.0 0.9 0.6 0.2 0.0 10.3 0.0 19.9 0.0 108.0 24.9 0.2 0.0 0.4 0.0 0.6 0.0 0.1 0.0 1.6 0.0 28.7 0.4 0.1 2.2 0.0 0.3 0.0 0.1 0.4 0.0 0.3 CDH8 ENSG00000150394 "Cadherin 8" P55286 16 61647242-62037035 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 22.4" "Group enriched" "Detected in some" 13 "Excitatory neurons: 220.8;Inhibitory neurons: 236.4;Oligodendrocytes: 145.7" "Cancer enhanced" "Detected in single" "testis cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 7.0;fHDF/TERT166: 6.3;HaCaT: 14.4;LHCN-M2: 17.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014908, HPA076441" Approved Approved "Plasma membrane" NA NA 870000 "Cluster 65: Brain - Ion transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014908: AB_1845908, HPA076441: " "unprognostic (1.91e-1)" "unprognostic (2.41e-1)" "unprognostic (4.02e-2)" "unprognostic (7.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.26e-2)" "unprognostic (1.83e-1)" "unprognostic (8.71e-2)" "unprognostic (3.66e-2)" "unprognostic (5.41e-2)" "unprognostic (2.85e-1)" "unprognostic (6.59e-2)" "unprognostic (2.91e-4)" "unprognostic (6.02e-2)" "unprognostic (4.06e-1)" "unprognostic (2.26e-1)" "unprognostic (1.06e-1)" 0.1 0.1 7.2 0.0 9.9 0.0 0.3 0.0 22.4 0.4 0.0 0.2 0.3 0.1 0.2 0.1 0.0 0.2 0.2 16.3 5.7 0.0 0.0 0.1 0.0 6.4 9.8 1.7 0.0 0.1 0.7 0.3 18.4 0.4 0.1 2.2 0.4 5.0 0.4 0.1 0.2 0.4 7.6 0.0 0.1 0.3 9.1 0.5 0.1 0.9 0.0 0.4 0.1 2.5 0.0 0.0 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 6.3 0.0 14.4 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.4 0.0 17.3 0.0 0.0 0.0 1.3 0.0 1.3 0.0 0.0 1.1 0.0 1.9 0.1 0.1 0.0 0.0 0.0 2.2 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 9.9 0.0 22.4 16.3 5.7 6.4 9.8 18.4 7.6 9.1 2.5 0.4 0.0 0.5 3.9 0.0 0.1 0.8 1.3 1.2 15.1 0.1 0.9 1.0 0.0 0.8 0.0 0.0 1.3 0.0 0.0 0.0 0.0 4.9 0.1 0.1 0.5 0.0 0.0 220.8 0.0 0.2 0.8 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.0 236.4 0.0 2.0 0.0 0.0 1.3 0.0 0.1 0.0 8.4 0.0 0.7 0.0 7.5 145.7 0.0 0.0 0.4 0.0 0.3 0.0 0.2 2.7 0.7 0.0 0.7 4.7 1.3 2.5 0.5 0.1 0.3 0.1 0.1 0.0 0.8 CDRT15 ENSG00000223510 "CMT1A duplicated region transcript 15" Q96T59 17 14235673-14236862 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 20.9" "Group enriched" "Detected in some" 24 "Early spermatids: 117.5;Late spermatids: 88.5;Spermatocytes: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 3.8" HPA055952 Uncertain Approved "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA055952: AB_2682983" "unprognostic (3.27e-2)" "unprognostic (1.77e-2)" "unprognostic (8.61e-2)" "unprognostic (9.33e-2)" "unprognostic (5.15e-3)" "unprognostic (2.90e-1)" "unprognostic (6.16e-3)" "unprognostic (1.98e-1)" "unprognostic (1.15e-3)" "unprognostic (2.66e-1)" "unprognostic (2.55e-1)" "unprognostic (1.99e-1)" "unprognostic (5.30e-7)" "unprognostic (1.55e-1)" "unprognostic (1.52e-1)" "unprognostic (6.81e-2)" "unprognostic (2.38e-2)" 0.1 0.4 0.1 1.2 0.2 0.6 0.1 1.4 0.5 0.2 0.4 0.2 0.7 0.2 0.2 0.3 0.1 0.4 0.3 0.3 0.0 0.1 0.4 0.3 2.7 0.6 0.1 0.4 0.2 0.0 0.1 0.1 0.6 0.2 0.0 0.4 0.7 0.0 0.1 3.3 0.8 0.0 0.1 0.9 0.4 20.9 0.2 0.0 0.5 0.0 0.0 0.1 0.2 0.1 0.7 1.3 0.9 2.0 0.0 0.0 0.5 0.8 0.0 0.0 0.0 2.5 0.3 2.1 0.4 0.0 0.3 0.9 0.0 0.0 0.0 2.1 3.8 1.2 2.6 1.8 0.0 1.0 1.5 0.0 0.0 0.0 0.0 0.7 0.0 1.0 1.0 0.4 0.0 0.5 1.0 1.6 0.8 1.5 1.2 0.8 0.3 0.8 0.0 1.0 1.0 1.8 0.2 0.5 0.3 2.7 0.4 0.5 1.1 3.2 0.4 0.8 0.9 0.7 0.8 0.9 0.5 1.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 1.4 0.5 0.3 0.0 0.6 0.1 0.6 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.5 3.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.4 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CEACAM5 "CD66e, CEA" ENSG00000105388 "CEA cell adhesion molecule 5" P06731 19 41708585-41730433 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion" "Cancer-related genes, Oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "intestine: 981.2" "Group enriched" "Detected in some" 4 "Distal enterocytes: 1389.2;Intestinal goblet cells: 395.0;Paneth cells: 777.3" "Cancer enhanced" "Detected in many" "colorectal cancer: 1007.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "OE19: 56.9" "CAB000021, CAB000022, HPA011041, HPA019758" Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA 23000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB000021: , CAB000022: AB_2335697, HPA011041: AB_1078481, HPA019758: AB_1846326" "unprognostic (1.54e-2)" "unprognostic (7.59e-2)" "unprognostic (5.49e-3)" "unprognostic (1.80e-1)" "unprognostic (1.38e-2)" "unprognostic (2.22e-1)" "unprognostic (3.49e-1)" "unprognostic (2.11e-1)" "unprognostic (2.19e-2)" "unprognostic (2.89e-1)" "unprognostic (8.67e-9)" "unprognostic (2.92e-1)" "unprognostic (2.71e-2)" "unprognostic (6.31e-2)" "unprognostic (1.85e-1)" 3.2 0.1 0.0 185.6 0.0 0.2 4.0 0.3 0.1 38.5 0.2 981.2 22.7 1.3 0.2 232.0 0.8 0.8 0.1 0.1 0.0 0.9 0.2 30.2 0.1 0.1 0.0 0.1 0.3 0.0 0.3 0.0 0.0 0.5 942.7 0.0 29.2 3.3 0.1 3.5 61.4 28.7 0.0 0.1 163.2 0.3 0.1 0.2 1.0 0.0 36.9 10.4 71.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.7 0.0 0.1 0.0 0.0 13.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 0.0 0.3 56.9 1.1 0.2 0.0 0.0 0.0 0.4 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.3 0.2 0.0 0.0 0.1 0.1 0.1 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 32.1 4.1 0.0 2.7 0.0 1.0 12.3 0.0 0.0 0.1 0.0 0.4 0.0 34.8 0.0 0.0 0.0 0.0 1389.2 0.0 3.4 0.4 0.0 0.0 0.2 65.7 0.0 0.1 0.9 0.0 0.4 22.4 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.1 395.0 4.1 0.0 0.4 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 21.3 777.3 0.0 0.1 16.5 10.2 0.0 4.5 0.0 0.0 0.1 0.4 0.8 0.5 1.9 0.0 0.0 1.2 0.0 192.3 124.4 CHRM3 ENSG00000133019 "Cholinergic receptor muscarinic 3" P20309 1 239386565-239915452 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.8;salivary gland: 17.5" "Group enriched" "Detected in many" 28 "Excitatory neurons: 802.9;Inhibitory neurons: 624.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RPMI-8226: 17.2;SH-SY5Y: 53.5;U-266/70: 21.7;U-266/84: 16.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA024106, HPA048036" Approved Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA024106: AB_1854211, HPA048036: AB_2680238" "unprognostic (1.63e-1)" "unprognostic (4.82e-2)" "unprognostic (1.05e-1)" "unprognostic (4.11e-3)" "unprognostic (3.48e-3)" "unprognostic (5.81e-2)" "unprognostic (2.30e-3)" "unprognostic (5.18e-2)" "unprognostic (1.71e-1)" "unprognostic (1.27e-1)" "unprognostic (6.29e-2)" "unprognostic (6.44e-2)" "unprognostic (5.34e-4)" "unprognostic (3.04e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (4.88e-2)" 0.3 0.4 4.6 0.8 7.3 0.2 0.8 0.0 11.8 0.4 0.0 7.0 1.4 1.9 0.4 7.5 0.8 0.7 0.4 7.5 0.0 1.1 0.4 1.1 0.1 0.0 0.0 4.8 10.6 0.5 0.5 0.8 0.0 1.1 2.8 1.7 17.5 3.0 0.0 1.3 1.5 4.1 0.0 0.7 5.0 2.5 4.1 0.1 2.0 0.1 0.1 7.0 0.4 2.9 0.0 0.1 0.4 0.4 0.0 0.0 0.9 0.6 0.1 0.3 0.1 0.0 0.0 0.0 2.1 0.0 0.0 5.8 0.6 3.8 2.7 0.0 3.7 0.6 0.4 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.8 0.0 0.0 1.1 9.1 0.9 1.4 0.0 0.0 4.6 4.6 9.1 0.0 1.1 17.2 0.7 0.8 0.1 53.5 0.0 0.1 0.1 4.0 1.8 0.0 0.3 2.3 0.8 0.1 0.5 21.7 16.3 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 7.3 0.0 11.8 7.5 0.0 0.0 0.0 0.0 0.0 4.1 2.9 6.1 0.0 3.7 6.2 0.0 0.0 2.1 0.0 0.6 19.0 4.6 3.2 1.2 0.0 0.8 0.0 0.0 3.2 0.3 11.0 1.9 0.4 19.6 0.1 0.1 3.0 3.5 4.6 802.9 17.3 0.7 3.9 11.7 0.2 1.3 7.5 4.2 0.3 0.5 0.0 624.0 6.0 0.0 0.0 0.0 3.9 0.0 0.2 7.2 22.5 0.0 0.3 0.0 8.5 11.2 2.6 25.3 0.4 0.2 2.5 2.2 1.4 1.6 0.6 0.0 0.2 1.1 12.9 3.0 0.2 0.0 0.5 0.1 0.8 15.5 0.2 CHRNA1 CHRNA ENSG00000138435 "Cholinergic receptor nicotinic alpha 1 subunit" P02708 2 174747592-174787935 "Disease related genes, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 8 "skeletal muscle: 170.1" "Cell type enriched" "Detected in some" 48 "Skeletal myocytes: 193.5" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Group enriched" "Detected in some" 13 "cerebral cortex: 12.8;hippocampal formation: 5.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "LHCN-M2: 445.4;RH-30: 360.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA071554 Enhanced Supported "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA071554: AB_2686416" "unprognostic (1.49e-1)" "unprognostic (1.97e-1)" "unprognostic (1.22e-3)" "unprognostic (2.28e-2)" "unprognostic (2.96e-1)" "unprognostic (8.55e-3)" "unprognostic (5.34e-2)" "unprognostic (5.29e-3)" "unprognostic (9.59e-2)" "unprognostic (9.64e-2)" "unprognostic (9.66e-2)" "unprognostic (6.37e-2)" "unprognostic (4.18e-4)" "unprognostic (2.04e-1)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (7.18e-2)" 0.2 0.0 0.2 0.2 0.4 0.0 0.5 0.1 12.8 0.6 0.2 1.5 0.2 0.0 0.2 0.6 0.0 0.0 0.3 5.5 0.2 0.0 0.2 0.6 0.8 0.5 0.2 0.0 0.0 0.0 3.3 0.2 0.5 2.0 0.9 0.0 3.2 0.0 170.1 0.5 0.0 0.0 0.3 0.0 0.0 0.4 0.3 1.1 0.0 20.4 1.2 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 21.5 0.0 0.2 0.0 0.0 1.4 0.0 0.1 0.2 445.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 360.2 0.0 0.0 0.3 2.9 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.4 0.1 12.8 5.5 0.2 0.5 0.2 0.5 0.3 0.3 0.7 0.1 0.0 0.0 0.0 2.8 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 4.0 0.0 0.0 1.7 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.5 0.0 0.6 0.4 1.7 0.3 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 193.5 0.3 0.1 0.2 0.0 0.0 0.0 1.8 0.0 0.2 0.0 CLDN4 "CPE-R, CPETR, CPETR1, hCPE-R, WBSCR8" ENSG00000189143 "Claudin 4" O14493 7 73799542-73832690 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Cancer-related genes, Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 305.0;urinary bladder: 303.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 3149.1;Glandular and luminal cells: 2298.8;Paneth cells: 2081.0;Prostatic glandular cells: 2184.8;Urothelial cells: 8033.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "midbrain: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 358.1;BEWO: 395.0;CAPAN-2: 761.4;MCF7: 400.2;OE19: 402.0;PC-3: 495.0;RT4: 340.2;SK-BR-3: 636.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" CAB002610 Enhanced Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "CAB002610: " "unprognostic (1.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.25e-1)" "unprognostic (1.23e-2)" "unprognostic (1.56e-2)" "unprognostic (1.84e-1)" "unprognostic (1.60e-2)" "unprognostic (7.09e-2)" "unprognostic (3.07e-1)" "prognostic unfavorable (3.28e-4)" "unprognostic (2.16e-3)" "unprognostic (5.11e-1)" "prognostic favorable (3.46e-10)" "unprognostic (5.77e-2)" "unprognostic (1.37e-1)" "unprognostic (9.38e-2)" "unprognostic (4.63e-2)" 2.6 0.4 0.1 23.0 0.0 0.2 69.0 0.8 0.3 61.2 4.8 256.3 126.9 26.7 24.4 305.0 75.8 48.9 0.4 0.2 0.0 116.2 4.8 64.0 1.0 0.4 1.5 1.2 116.2 51.9 13.1 36.3 0.3 82.2 123.3 0.3 204.6 39.1 0.5 180.8 190.6 7.3 0.0 0.7 13.3 0.6 0.2 10.7 111.7 0.3 37.5 303.5 105.7 0.0 358.1 4.4 0.0 1.5 0.0 0.4 395.0 3.3 0.2 0.3 0.4 184.9 761.4 0.6 28.0 0.1 2.6 193.3 0.0 0.5 0.4 0.7 0.4 0.2 20.3 127.0 0.1 0.1 0.9 0.0 1.9 0.1 0.4 0.3 0.0 0.2 0.3 0.7 0.0 400.2 0.7 1.9 0.7 402.0 495.0 0.5 6.9 7.6 92.4 340.2 79.5 1.7 0.4 636.8 0.8 21.6 250.9 0.9 0.5 0.9 13.7 3.1 3.5 0.9 0.7 0.7 0.6 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.3 0.2 0.0 0.4 1.5 0.3 0.0 0.2 0.0 5.1 275.7 230.2 0.0 12.2 16.2 3149.1 641.6 31.3 0.4 1255.2 548.4 0.8 287.4 954.3 218.8 0.0 771.7 18.7 1985.0 13.7 1026.1 0.0 1201.7 231.0 41.3 675.5 0.0 0.2 447.1 739.7 27.0 94.8 2298.8 27.3 0.2 0.4 0.5 76.3 0.0 0.1 1266.9 905.3 0.6 8.6 0.0 2.5 29.3 14.2 0.0 15.6 0.8 0.0 0.0 0.0 950.2 2081.0 0.0 2.5 2184.8 1906.1 21.6 635.6 0.0 0.0 0.1 68.2 0.0 0.2 1068.1 54.0 956.1 40.7 0.1 965.1 8033.4 CLEC2A "INPE5792, KACL, PILAR, UNQ5792" ENSG00000188393 "C-type lectin domain family 2 member A" Q6UVW9 12 9898673-9932370 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 57.6" "Group enriched" "Detected in some" 11 "Basal keratinocytes: 18.7;Suprabasal keratinocytes: 37.1" "Cancer enhanced" "Detected in some" "cervical cancer: 1.1" "Region enhanced" "Detected in single" "cerebellum: 2.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "fHDF/TERT166: 22.0;U-937: 54.6" "HPA048530, HPA072407" Approved Uncertain "Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 32: U-937 - Innate immune response" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA048530: AB_2680429, HPA072407: AB_2686518" "unprognostic (3.10e-1)" "unprognostic (5.29e-2)" "unprognostic (2.23e-1)" 0.0 0.0 0.1 0.0 0.2 0.0 3.5 2.1 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.2 57.6 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.1 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 22.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 54.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 2.1 0.3 0.2 0.3 0.5 0.3 0.5 0.1 0.3 0.6 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 37.1 0.0 0.1 0.0 0.0 0.1 CMTM7 "CKLFSF7, FLJ30992" ENSG00000153551 "CKLF like MARVEL transmembrane domain containing 7" Q96FZ5 3 32391698-32483067 "Predicted membrane proteins, Transporters" Chemotaxis Cytokine "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 102.3;Ductal cells: 105.6;Hofbauer cells: 120.3;Kupffer cells: 110.7;Langerhans cells: 102.8;monocytes: 108.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "CAPAN-2: 135.4;hTERT-RPE1: 135.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077409 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA077409: AB_2686838" "unprognostic (2.27e-3)" "unprognostic (3.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.15e-1)" "unprognostic (5.42e-2)" "unprognostic (3.16e-2)" "prognostic unfavorable (3.21e-4)" "unprognostic (3.03e-2)" "unprognostic (3.92e-2)" "unprognostic (2.60e-1)" "unprognostic (6.55e-3)" "unprognostic (1.64e-1)" "prognostic unfavorable (1.00e-6)" "unprognostic (5.86e-2)" "unprognostic (2.51e-1)" "unprognostic (3.79e-1)" "unprognostic (3.12e-2)" 22.8 10.4 7.5 20.7 7.7 43.7 32.6 8.6 12.9 15.2 8.7 8.4 5.3 11.1 10.9 3.9 38.7 16.0 10.1 7.3 8.2 22.1 10.1 33.0 32.2 8.9 8.3 5.5 19.9 4.0 3.7 19.2 9.2 12.1 9.3 0.6 13.1 19.9 4.0 10.1 18.3 10.5 8.7 49.3 13.4 8.6 9.5 46.1 20.5 3.1 31.4 24.1 7.2 10.8 0.4 15.8 32.8 40.2 29.8 29.0 93.4 15.5 18.0 26.5 24.3 18.0 135.4 0.1 46.7 18.1 33.0 17.4 40.6 69.1 23.2 0.0 32.8 18.5 0.1 40.6 120.8 4.7 29.0 31.0 9.0 27.2 42.6 135.1 60.0 0.2 15.8 40.9 19.6 0.4 0.2 42.9 39.7 7.0 71.7 90.5 12.3 85.0 37.7 30.9 1.6 33.9 2.0 2.6 80.8 13.9 21.3 48.7 36.2 25.3 25.5 27.9 54.4 11.6 4.6 0.2 9.3 57.9 54.2 32.4 198.7 110.8 21.3 196.8 12.7 44.2 72.1 44.2 106.8 34.7 76.5 54.1 77.3 21.6 173.6 45.0 164.1 112.6 7.5 7.7 8.6 12.9 7.3 8.2 8.9 8.3 9.2 8.7 9.5 10.8 10.3 25.6 16.7 1.0 65.5 9.8 20.2 102.3 1.8 0.5 63.4 86.0 2.1 28.6 51.9 18.4 0.0 22.2 25.0 2.0 0.0 105.6 0.2 17.4 12.8 24.2 17.3 11.6 0.5 15.5 10.0 15.2 26.0 33.1 29.8 29.0 20.7 1.3 120.3 1.7 1.4 4.4 40.7 110.7 102.8 1.2 1.5 77.2 24.9 20.6 108.1 1.4 12.3 1.0 0.3 91.8 8.1 1.2 62.9 42.0 1.2 27.5 23.3 0.2 6.6 1.2 13.5 1.2 10.4 0.9 5.5 6.8 57.4 6.1 2.8 16.3 CNP ENSG00000173786 "2',3'-cyclic nucleotide 3' phosphodiesterase" P09543 17 41966763-41977740 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "brain: 1395.7" "Cell type enriched" "Detected in all" 4 "Oligodendrocytes: 555.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 149.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Region enriched" "Detected in all" 4 "white matter: 1789.4" "Low region specificity" "Detected in all" "CAB002672, HPA023266, HPA023278, HPA023280, HPA023338" Enhanced Supported Supported "Plasma membrane" NA NA 46000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002672: , HPA023266: AB_1847058, HPA023278: AB_1847060, HPA023280: AB_1847061, HPA023338: AB_1847062" "unprognostic (2.17e-1)" "unprognostic (4.48e-2)" "unprognostic (3.85e-3)" "unprognostic (1.41e-1)" "unprognostic (3.09e-1)" "unprognostic (9.71e-2)" "unprognostic (2.58e-3)" "unprognostic (2.08e-1)" "unprognostic (2.23e-1)" "unprognostic (1.62e-1)" "unprognostic (5.76e-3)" "unprognostic (1.87e-1)" "unprognostic (2.99e-3)" "unprognostic (1.60e-1)" "unprognostic (1.55e-1)" "unprognostic (8.86e-2)" "unprognostic (1.10e-3)" 34.4 33.5 493.1 31.2 889.6 23.4 29.6 715.5 681.5 41.7 193.5 56.9 21.4 33.5 36.7 63.4 28.9 32.6 25.3 505.1 577.0 58.1 44.8 21.7 35.7 839.4 761.8 32.2 27.8 23.7 28.1 23.5 793.8 41.5 18.4 20.5 47.2 37.2 26.3 34.3 31.4 30.3 644.6 25.8 29.8 16.7 791.1 31.2 24.7 22.2 35.1 37.3 40.5 1395.7 56.9 92.4 85.8 106.6 71.7 67.2 38.5 70.1 102.5 171.1 191.5 73.0 49.6 59.0 54.3 88.5 88.1 95.0 58.3 44.6 59.0 59.7 76.8 56.7 59.3 127.7 76.9 56.7 49.6 111.0 31.5 94.1 22.8 61.9 79.4 58.0 42.4 46.4 60.6 35.1 148.5 50.9 20.7 29.8 66.5 91.4 126.7 58.7 45.7 55.7 50.9 69.5 85.7 127.0 155.5 41.6 57.2 82.3 80.2 66.6 73.7 92.3 81.9 53.4 66.6 47.5 66.1 42.9 266.4 18.7 38.2 23.4 21.5 40.7 17.2 28.0 18.8 17.4 33.8 19.2 16.6 19.6 7.7 23.5 34.0 149.4 22.4 33.0 493.1 889.6 715.5 681.5 505.1 577.0 839.4 761.8 793.8 644.6 791.1 1395.7 26.6 16.0 12.7 14.4 19.0 16.7 17.5 10.4 16.5 22.0 29.5 24.0 13.0 20.0 19.5 35.0 6.2 30.6 53.2 39.9 125.2 46.3 1.3 19.1 27.1 24.8 19.7 25.2 6.8 41.7 50.2 27.7 17.9 21.3 9.5 20.2 20.3 32.3 39.8 50.5 9.5 16.2 18.3 17.0 14.5 4.0 38.8 20.3 55.2 14.0 25.0 84.7 23.7 45.2 555.6 35.5 19.0 36.1 27.8 21.7 19.0 80.5 12.8 25.4 32.9 36.6 29.4 5.1 16.0 30.9 18.9 13.0 16.9 33.3 20.6 17.4 COL5A3 ENSG00000080573 "Collagen type V alpha 3 chain" P25940 19 9959561-10010504 "Cancer-related genes, Predicted secreted proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 5 "Astrocytes: 510.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC TERT1: 38.9;BJ: 23.6;BJ hTERT+: 26.2;BJ hTERT+ SV40 Large T+: 14.4;HSkMC: 28.2;WM-115: 26.2" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA041695, HPA048256" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 330000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA041695: , HPA048256: AB_2680330" "unprognostic (1.17e-1)" "unprognostic (1.35e-2)" "unprognostic (4.63e-2)" "unprognostic (3.24e-2)" "unprognostic (6.84e-3)" "unprognostic (3.01e-1)" "unprognostic (7.47e-2)" "unprognostic (1.79e-2)" "unprognostic (2.36e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-2)" "unprognostic (2.09e-1)" "prognostic unfavorable (7.17e-8)" "unprognostic (3.25e-2)" "unprognostic (7.31e-3)" "unprognostic (6.00e-2)" "prognostic unfavorable (6.87e-5)" 47.4 5.0 33.2 9.9 33.2 0.1 32.3 30.6 45.9 44.9 43.6 19.3 3.7 27.3 1.9 9.0 22.8 4.1 33.5 33.3 26.4 7.9 13.4 14.2 3.2 35.2 30.2 6.3 5.2 3.0 3.5 32.8 32.3 16.6 2.0 21.1 7.3 8.9 15.3 21.7 11.7 10.3 31.0 1.7 9.9 4.7 30.2 4.5 12.7 6.0 3.9 12.6 26.4 28.4 0.0 0.0 0.5 0.0 12.4 38.9 0.0 23.6 26.2 14.4 5.7 0.0 0.0 0.0 0.2 4.4 0.3 2.3 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 28.2 0.6 5.2 5.5 0.0 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 6.6 0.1 0.0 0.0 0.0 11.6 5.5 0.5 0.0 0.0 0.0 0.0 1.5 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 33.2 33.2 30.6 45.9 33.3 26.4 35.2 30.2 32.3 31.0 30.2 28.4 13.7 0.0 0.0 510.3 0.0 4.2 0.1 0.2 2.2 65.1 0.3 0.9 6.4 0.0 0.1 0.0 6.2 0.1 0.3 1.3 0.0 0.2 6.9 0.4 12.0 8.1 0.0 0.0 15.6 0.0 0.2 17.5 0.5 0.4 0.0 0.0 3.9 22.9 0.6 3.3 3.4 0.0 0.0 0.0 3.2 2.1 17.4 0.4 14.2 36.5 0.1 2.6 0.0 73.9 2.5 0.3 0.1 8.2 0.0 0.3 0.2 0.1 0.9 28.3 92.1 8.5 58.0 0.3 0.3 3.2 7.1 0.1 1.9 0.9 0.0 0.3 CPZ ENSG00000109625 "Carboxypeptidase Z" Q66K79 4 8592660-8619759 "Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Wnt signaling pathway" "Carboxypeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 144.3" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 1.5;Fibroblasts: 8.5;Microglial cells: 2.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 73.6;BJ: 39.7;BJ hTERT+: 51.7;hTERT-RPE1: 30.6;RH-30: 57.6;U-2197: 46.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA078608 Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA078608: " "unprognostic (2.58e-1)" "unprognostic (7.16e-2)" "unprognostic (4.83e-2)" "unprognostic (1.42e-1)" "unprognostic (7.77e-2)" "unprognostic (2.20e-2)" "unprognostic (2.98e-1)" "unprognostic (7.77e-2)" "unprognostic (2.30e-1)" "unprognostic (1.95e-2)" "unprognostic (1.41e-1)" "unprognostic (1.59e-1)" "unprognostic (7.23e-8)" "unprognostic (4.30e-3)" "unprognostic (3.58e-2)" "unprognostic (6.13e-4)" "unprognostic (5.51e-2)" 11.1 1.8 0.3 2.7 1.0 0.0 11.8 0.5 2.9 33.3 2.3 4.6 0.8 14.6 9.1 7.4 19.9 30.7 2.8 0.8 0.4 2.0 1.4 7.1 2.8 0.7 0.5 144.3 3.2 1.8 5.2 42.1 0.8 5.9 1.8 0.1 1.5 24.2 0.2 13.8 2.6 8.4 1.2 1.4 3.3 3.1 0.3 1.5 7.8 0.0 1.0 23.0 25.1 0.9 26.1 0.4 0.0 1.6 5.0 0.5 73.6 39.7 51.7 14.5 5.8 1.7 0.7 0.0 3.7 21.3 0.3 0.0 0.0 0.0 5.4 0.0 2.9 0.0 0.3 0.7 4.4 0.0 0.0 9.2 0.0 0.0 0.0 30.6 0.0 0.0 1.2 0.0 0.9 6.1 0.0 0.1 9.2 0.2 22.0 0.1 57.6 0.0 0.0 1.1 0.1 0.1 1.4 0.5 0.1 8.3 0.3 0.0 0.0 2.0 2.6 46.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.5 2.9 0.8 0.4 0.7 0.5 0.8 1.2 0.3 0.9 0.0 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.6 0.0 0.6 8.5 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.1 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.0 CRHR2 "CRF-RB, CRF2, HM-CRF" ENSG00000106113 "Corticotropin releasing hormone receptor 2" Q13324 7 30651942-30700129 "G-protein coupled receptors, Predicted membrane proteins, Predicted secreted proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.0;choroid plexus: 21.7" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 3.0;Excitatory neurons: 8.2;Horizontal cells: 13.5;Inhibitory neurons: 4.9;Smooth muscle cells: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 8.1" "Low region specificity" "Detected in many" HPA073345 Supported "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA073345: " "unprognostic (7.14e-2)" "unprognostic (4.20e-1)" "unprognostic (1.68e-1)" "unprognostic (1.24e-3)" "unprognostic (5.69e-2)" "unprognostic (8.58e-2)" "unprognostic (6.00e-2)" "unprognostic (1.86e-4)" "unprognostic (2.01e-1)" "unprognostic (3.07e-1)" "unprognostic (5.90e-4)" "unprognostic (4.02e-2)" "unprognostic (8.29e-4)" "unprognostic (3.73e-3)" "unprognostic (2.84e-3)" "unprognostic (1.81e-1)" "unprognostic (3.84e-1)" 0.6 0.0 1.5 0.0 1.0 0.0 0.6 0.4 6.0 0.3 21.7 0.2 0.3 0.3 0.0 0.2 0.5 0.1 2.1 2.3 1.0 0.8 0.0 0.1 0.0 1.4 1.0 0.4 1.7 0.1 4.2 0.0 0.4 0.2 0.1 2.5 0.3 1.3 1.2 0.2 0.3 0.1 0.4 0.0 0.2 0.8 2.8 0.0 0.7 2.2 0.0 0.3 0.2 2.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.0 0.4 6.0 2.3 1.0 1.4 1.0 0.4 0.4 2.8 2.4 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.5 4.9 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 2.3 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CRK ENSG00000167193 "CRK proto-oncogene, adaptor protein" P46108 17 1420689-1463162 "Predicted intracellular proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010485, HPA068087" Approved Approved "Plasma membrane" NA NA 400000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 39: CACO-2 - Unknown function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010485: AB_2085043, HPA068087: AB_2685950" "unprognostic (6.82e-3)" "unprognostic (1.94e-1)" "unprognostic (8.70e-3)" "unprognostic (5.34e-2)" "unprognostic (2.43e-1)" "unprognostic (3.32e-2)" "unprognostic (2.48e-1)" "unprognostic (1.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.88e-1)" "unprognostic (2.65e-1)" "unprognostic (5.35e-2)" "unprognostic (1.96e-1)" "unprognostic (1.67e-1)" "unprognostic (3.77e-1)" "unprognostic (1.56e-1)" "unprognostic (3.93e-2)" 48.2 23.2 27.9 20.8 28.3 5.7 30.6 28.1 27.8 26.4 25.2 34.1 26.8 28.2 32.1 26.9 21.0 29.7 27.7 28.2 28.5 31.5 50.1 30.2 17.3 29.6 29.7 24.8 27.3 25.3 11.2 42.2 29.4 23.9 34.4 22.6 23.8 27.0 32.0 20.4 24.2 35.6 30.1 20.4 26.1 20.5 31.2 17.6 36.7 37.9 20.1 31.6 21.8 29.3 45.9 69.8 50.8 54.6 83.7 70.2 47.5 77.3 64.8 59.7 55.3 90.7 26.3 22.0 37.6 89.1 41.7 69.1 68.2 55.8 87.2 11.1 46.6 24.5 43.7 50.2 77.9 10.6 20.9 68.3 64.7 61.9 77.1 45.8 74.3 20.2 42.1 20.3 84.4 46.3 11.5 12.1 46.3 50.4 34.6 24.3 25.7 20.1 78.4 48.4 18.8 49.2 73.5 45.2 54.6 47.7 44.5 17.7 79.8 59.7 33.9 63.8 77.3 9.6 15.8 13.5 50.4 20.6 66.6 6.2 3.9 5.3 3.0 4.2 3.0 3.6 3.2 2.7 4.4 5.2 2.4 3.5 13.9 2.7 4.4 3.9 2.6 1.7 27.9 28.3 28.1 27.8 28.2 28.5 29.6 29.7 29.4 30.1 31.2 29.3 89.5 67.3 51.5 12.7 34.6 149.5 68.8 29.6 50.7 43.8 62.7 45.5 35.2 48.6 33.8 33.1 27.1 63.3 22.1 92.6 41.1 62.1 4.3 55.2 64.5 89.7 49.8 39.5 17.5 65.3 61.6 52.7 47.4 94.1 7.6 33.0 92.8 65.6 45.3 53.8 17.6 61.9 22.4 47.1 91.6 8.3 43.8 46.3 53.4 19.7 45.3 43.5 24.7 12.5 13.6 76.7 60.5 44.0 25.7 77.9 58.3 39.7 32.6 38.9 46.0 59.6 72.9 29.0 58.6 62.8 167.8 85.0 29.9 35.4 66.4 92.2 CRYBG3 DKFZp667G2110 ENSG00000080200 "Crystallin beta-gamma domain containing 3" Q68DQ2 3 97822011-97944984 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 122.6;Bipolar cells: 123.6;Early spermatids: 121.4;Late spermatids: 131.8;Oligodendrocytes: 128.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.6" "Group enriched" "Detected in many" 8 "dendritic cells: 3.6;granulocytes: 1.5;monocytes: 1.4" "Cell line enhanced" "Detected in many" "SCLC-21H: 39.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA075635 Approved "Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 57: Non-specific - Angiogenesis" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075635: " "unprognostic (1.88e-1)" "unprognostic (7.62e-3)" "unprognostic (2.54e-1)" "unprognostic (4.56e-2)" "unprognostic (7.60e-2)" "unprognostic (2.70e-2)" "unprognostic (2.45e-2)" "unprognostic (7.10e-2)" "unprognostic (3.41e-3)" "unprognostic (6.59e-2)" "unprognostic (2.80e-2)" "unprognostic (7.86e-2)" "prognostic favorable (7.07e-4)" "unprognostic (1.78e-2)" "unprognostic (1.58e-1)" "unprognostic (1.14e-2)" "unprognostic (6.38e-3)" 10.6 2.8 5.3 5.5 12.6 0.8 7.7 9.2 8.0 8.0 3.4 7.0 3.6 6.6 2.7 8.9 5.6 5.3 6.5 5.3 10.6 4.9 3.2 5.7 3.4 15.5 10.0 3.5 5.4 3.7 1.2 10.7 16.0 5.0 7.6 7.8 6.3 4.1 7.5 12.9 4.5 6.4 11.3 4.0 5.3 14.0 10.0 2.8 26.6 9.9 4.5 7.5 4.6 17.2 16.5 6.1 3.5 4.2 11.1 11.8 6.2 5.8 5.3 4.2 6.3 0.4 5.4 0.1 1.9 10.1 6.2 10.5 7.0 4.9 8.0 20.4 3.8 4.1 2.7 2.1 5.8 6.1 1.0 7.7 4.9 5.3 5.8 6.9 8.2 1.3 0.3 3.0 7.4 0.2 2.2 0.7 3.0 4.5 5.5 0.0 12.3 2.1 6.1 10.9 39.2 3.0 12.2 4.8 3.9 2.2 4.2 6.8 10.9 8.9 6.9 5.2 7.1 5.0 0.1 3.7 9.3 3.5 5.8 1.5 1.4 0.0 0.1 0.9 0.2 0.1 0.2 0.2 1.4 0.2 0.1 0.1 0.0 0.0 1.0 3.6 0.0 0.3 5.3 12.6 9.2 8.0 5.3 10.6 15.5 10.0 16.0 11.3 10.0 17.2 122.6 32.1 19.6 48.0 4.2 5.1 7.0 3.7 23.9 123.6 13.7 9.3 37.6 1.5 16.9 18.4 6.2 4.0 13.8 6.0 1.9 8.8 121.4 32.6 48.9 52.1 12.7 2.5 37.5 13.1 11.3 38.0 18.3 22.7 0.0 68.0 15.0 5.1 6.6 13.5 23.0 8.3 2.0 17.4 3.0 131.8 8.4 18.9 8.8 37.5 22.1 29.4 1.0 10.6 128.3 13.2 8.7 4.5 12.0 7.1 2.5 2.8 21.3 9.6 39.5 29.2 18.2 49.6 9.5 24.5 6.1 2.3 3.0 14.0 5.2 7.0 CSMD3 ENSG00000164796 "CUB and Sushi multiple domains 3" Q7Z407 8 112222928-113436939 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 6.8" "Group enriched" "Detected in some" 12 "Excitatory neurons: 915.9;Inhibitory neurons: 867.9;Oligodendrocyte precursor cells: 1761.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029007, HPA029008" Uncertain Approved "Plasma membrane" NA NA "Cluster 65: Brain - Ion transport" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029007: AB_10601802, HPA029008: " "unprognostic (2.26e-1)" "unprognostic (2.16e-2)" "unprognostic (2.83e-2)" "unprognostic (5.97e-2)" "unprognostic (3.44e-2)" "unprognostic (1.26e-2)" "unprognostic (3.54e-4)" "unprognostic (2.48e-1)" "unprognostic (2.54e-1)" "unprognostic (2.89e-2)" "unprognostic (2.33e-2)" "unprognostic (5.03e-10)" "unprognostic (1.95e-1)" "unprognostic (4.14e-3)" "unprognostic (1.91e-2)" "unprognostic (1.74e-3)" 0.0 0.0 6.8 0.0 4.3 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 5.7 4.8 0.0 0.0 0.0 0.0 1.9 2.7 0.0 0.2 0.0 0.1 0.0 1.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.9 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 4.3 0.0 6.0 5.7 4.8 1.9 2.7 1.6 0.8 5.0 0.7 0.0 0.0 3.0 21.5 0.2 0.3 0.1 0.0 0.0 7.3 0.0 0.0 1.6 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.8 0.5 0.1 0.4 0.0 0.0 915.9 0.0 0.0 0.9 0.0 0.2 0.0 4.6 0.0 0.0 0.0 0.0 867.9 0.0 0.0 0.0 0.8 6.3 0.0 0.3 0.0 19.7 0.0 0.5 0.0 1761.3 92.2 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.9 0.0 0.4 0.2 17.1 8.2 0.0 0.6 0.0 0.0 0.0 0.0 0.3 CTNNB1 "armadillo, beta-catenin, CTNNB" ENSG00000168036 "Catenin beta 1" P35222 3 41194741-41260096 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Host-virus interaction, Neurogenesis, Transcription, Transcription regulation, Wnt signaling pathway" Activator "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 539.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000108, CAB001950, HPA029159, HPA029160" Supported Enhanced "Plasma membrane" NA NA 2000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB000108: , CAB001950: , HPA029159: AB_10599619, HPA029160: AB_10600996" "unprognostic (2.47e-1)" "unprognostic (3.48e-2)" "prognostic favorable (7.54e-4)" "unprognostic (1.61e-1)" "unprognostic (9.55e-2)" "unprognostic (1.05e-2)" "unprognostic (3.20e-3)" "unprognostic (2.79e-1)" "unprognostic (1.57e-1)" "unprognostic (1.80e-2)" "unprognostic (1.88e-2)" "unprognostic (9.05e-2)" "unprognostic (1.97e-3)" "unprognostic (1.82e-2)" "unprognostic (1.17e-1)" "unprognostic (2.61e-1)" "unprognostic (9.79e-2)" 130.8 112.2 106.7 98.7 85.3 162.4 194.3 147.8 87.5 179.4 94.7 141.2 136.9 149.4 84.4 113.7 131.0 121.8 109.9 88.1 105.3 106.5 147.9 132.9 81.9 101.3 112.9 173.9 93.3 137.2 84.7 200.0 94.0 132.3 134.5 88.8 110.9 126.3 87.3 99.0 142.9 178.4 104.9 92.5 81.8 59.5 129.4 95.6 140.6 89.9 99.5 158.3 109.3 108.4 161.6 210.0 423.6 242.8 226.9 184.7 333.8 179.6 249.7 288.2 284.3 146.3 224.0 131.7 157.8 314.1 129.0 119.6 315.8 510.0 306.2 123.3 215.7 215.5 261.0 523.7 169.5 121.8 99.1 271.6 226.7 345.5 208.7 235.7 258.1 63.0 153.7 80.3 324.1 161.8 87.3 68.3 397.2 211.0 159.3 64.9 281.9 88.3 177.9 494.8 102.9 172.4 296.2 147.1 809.4 509.8 242.1 248.6 340.8 217.1 163.6 139.3 264.0 50.7 82.7 138.4 221.5 150.5 369.7 4.7 7.3 6.4 9.2 12.3 10.9 7.7 8.6 10.1 11.8 8.0 8.6 9.4 6.6 9.6 12.6 10.0 10.8 5.6 106.7 85.3 147.8 87.5 88.1 105.3 101.3 112.9 94.0 104.9 129.4 108.4 171.7 137.8 179.5 58.1 71.7 213.5 130.1 75.3 116.1 40.7 232.5 168.1 84.7 90.1 119.2 62.5 33.3 318.9 99.0 251.6 35.2 132.2 11.0 90.3 125.9 187.3 93.8 43.8 50.9 78.5 115.6 116.8 53.0 95.5 116.6 137.0 139.2 172.5 115.1 13.5 82.4 145.9 42.7 154.6 228.1 9.5 59.7 161.1 202.7 124.6 98.3 89.2 49.4 70.9 62.9 139.8 249.5 86.9 55.5 128.3 160.3 93.2 96.1 62.0 46.0 175.6 137.3 78.4 40.1 70.9 174.9 539.5 77.0 245.6 189.6 127.9 CTNND1 "CTNND, KIAA0384, p120, p120cas, p120ctn" ENSG00000198561 "Catenin delta 1" O60716 11 57753243-57819546 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell adhesion, Transcription, Transcription regulation, Wnt signaling pathway" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 305.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 4.9;intermediate monocyte: 9.5;myeloid DC: 6.3;non-classical monocyte: 5.6" "Group enriched" "Detected in many" 19 "dendritic cells: 6.3;monocytes: 9.5" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB003837, HPA015954, HPA015955" Enhanced Enhanced "Plasma membrane" NA NA 200000 "Cluster 7: Monocytes - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "CAB003837: AB_562066, HPA015954: AB_2669326, HPA015955: AB_1846068" "unprognostic (1.06e-2)" "unprognostic (1.60e-2)" "unprognostic (5.17e-3)" "unprognostic (4.87e-2)" "unprognostic (7.81e-2)" "unprognostic (2.30e-1)" "unprognostic (2.98e-2)" "unprognostic (3.52e-3)" "unprognostic (4.17e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (3.02e-4)" "unprognostic (2.75e-1)" "prognostic favorable (3.54e-4)" "unprognostic (7.17e-2)" "unprognostic (4.09e-2)" "unprognostic (3.34e-1)" "unprognostic (7.33e-2)" 72.6 48.8 29.6 34.8 28.1 5.9 83.3 28.2 33.0 86.0 50.0 107.9 97.8 70.8 49.3 209.7 58.4 56.3 49.0 26.6 26.8 77.9 82.6 83.9 19.0 34.8 30.6 49.3 120.0 76.1 57.7 106.0 32.5 78.9 102.0 23.5 121.8 57.1 26.8 129.4 104.9 54.8 32.3 51.5 105.4 44.3 38.0 24.4 98.6 19.9 48.4 83.5 111.9 33.5 156.6 106.4 70.2 63.3 46.1 71.6 141.7 65.1 78.8 58.5 55.6 88.5 163.9 1.0 113.2 72.5 50.9 201.7 58.8 97.4 71.1 1.0 21.9 32.0 35.8 109.9 52.6 5.0 52.7 70.0 133.5 67.1 73.5 103.8 197.2 1.7 55.1 0.4 55.1 48.0 1.7 13.9 54.7 101.2 56.5 0.7 67.4 1.3 90.2 171.0 4.9 40.1 91.5 133.6 113.1 176.3 138.9 6.1 166.0 59.6 50.3 53.2 34.6 1.2 0.9 2.3 53.2 3.4 111.5 0.0 4.9 0.1 0.0 9.5 0.2 0.2 0.0 0.1 6.3 0.3 0.0 0.0 0.2 0.4 5.6 1.4 0.1 1.1 29.6 28.1 28.2 33.0 26.6 26.8 34.8 30.6 32.5 32.3 38.0 33.5 116.2 147.4 84.0 0.0 8.8 117.1 96.9 82.9 126.9 21.0 101.5 70.5 17.5 125.8 96.6 141.6 39.6 94.0 2.3 305.5 13.7 106.7 14.1 91.1 58.5 98.6 86.2 21.3 0.0 97.2 85.6 34.5 165.1 139.4 32.4 61.1 91.8 127.6 44.4 15.2 0.0 160.7 52.9 64.3 55.5 10.5 28.3 46.4 48.0 0.0 28.5 30.2 2.1 0.0 0.0 141.8 169.3 38.4 5.0 116.9 179.6 57.6 88.2 26.4 26.3 32.3 38.1 37.0 21.1 285.1 200.5 90.8 6.2 39.9 127.0 194.6 CX3CL1 "ABCD-3, C3Xkine, CXC3, CXC3C, NTN, SCYD1" ENSG00000006210 "C-X3-C motif chemokine ligand 1" P78423 16 57372477-57385044 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Chemotaxis, Host-virus interaction, Inflammatory response" Cytokine "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 104.8" "Cell type enhanced" "Detected in many" "Adipocytes: 115.4;Basal prostatic cells: 50.8;Basal respiratory cells: 51.8;Breast glandular cells: 62.3;Breast myoepithelial cells: 51.1;Club cells: 54.8;Endothelial cells: 50.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "EFO-21: 30.1;HDLM-2: 86.0;Hep G2: 63.8;RPTEC TERT1: 36.5;SK-BR-3: 21.5" "Low region specificity" "Detected in all" "CAB026192, HPA040361" Approved Supported "Plasma membrane" "Secreted to blood" NA NA 1870000 370000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB026192: , HPA040361: AB_10796453" "unprognostic (6.89e-3)" "prognostic favorable (9.46e-4)" "unprognostic (1.52e-2)" "unprognostic (3.20e-2)" "unprognostic (1.73e-1)" "unprognostic (1.82e-1)" "unprognostic (7.12e-2)" "unprognostic (2.08e-3)" "unprognostic (4.49e-2)" "unprognostic (3.70e-1)" "unprognostic (2.59e-2)" "unprognostic (2.06e-2)" "prognostic favorable (8.52e-7)" "unprognostic (5.19e-2)" "unprognostic (2.72e-1)" "unprognostic (1.11e-2)" "unprognostic (9.33e-2)" 68.3 4.8 36.4 5.7 39.5 0.1 104.8 11.9 44.8 17.6 19.8 14.3 5.1 13.7 8.7 14.4 18.2 21.0 43.0 46.9 26.4 41.9 14.9 98.8 8.5 25.1 24.8 8.3 13.1 7.1 11.2 3.9 23.6 42.2 5.4 4.3 70.8 45.3 15.0 27.3 12.8 10.6 21.8 1.4 14.5 5.7 30.5 5.2 29.7 19.2 6.2 33.0 17.3 31.2 0.0 0.8 8.0 6.8 0.3 0.1 2.0 0.1 0.0 0.0 0.1 3.1 0.0 0.0 30.1 0.1 4.3 0.3 0.0 0.1 0.0 86.0 0.4 0.0 0.0 63.8 0.9 0.0 0.1 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.4 2.8 0.1 0.0 0.1 1.1 0.2 36.5 0.2 0.2 7.1 0.0 21.5 1.9 5.1 0.1 0.2 0.1 0.3 4.7 0.2 2.1 0.1 0.0 0.0 0.1 0.0 1.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 36.4 39.5 11.9 44.8 46.9 26.4 25.1 24.8 23.6 21.8 30.5 31.2 115.4 3.2 4.6 3.3 1.2 4.5 50.8 51.8 31.9 9.8 62.3 51.1 8.3 21.5 54.8 3.7 4.2 0.0 0.8 0.5 0.0 35.1 0.4 12.9 3.3 50.7 1.8 0.0 28.1 1.8 0.1 9.0 0.5 27.3 1.3 0.2 6.1 11.7 0.0 5.0 20.5 0.3 20.3 0.8 4.7 0.5 4.7 0.6 0.0 16.9 0.6 0.8 0.0 13.0 3.2 4.3 0.6 27.8 0.0 29.7 0.2 11.8 28.8 2.2 13.1 2.8 15.7 0.1 0.1 10.3 2.6 0.3 0.8 0.3 1.0 32.6 CX3CR1 "CCRL1, CMKBRL1, CMKDR1, GPR13, V28" ENSG00000168329 "C-X3-C motif chemokine receptor 1" P49238 3 39263495-39281735 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Age-related macular degeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 26.4" "Group enriched" "Detected in some" 5 "Microglial cells: 177.1;NK-cells: 350.1" "Cancer enriched" "Detected in many" 4 "glioma: 21.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 449.2" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 21 "RPMI-8226: 589.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB032478, HPA046587" Approved Approved "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB032478: AB_638830, HPA046587: AB_2679708" "unprognostic (2.00e-1)" "unprognostic (5.12e-2)" "unprognostic (2.65e-1)" "unprognostic (2.42e-2)" "unprognostic (6.52e-2)" "unprognostic (3.01e-3)" "unprognostic (2.64e-1)" "unprognostic (1.16e-2)" "unprognostic (3.98e-2)" "unprognostic (1.57e-3)" "unprognostic (1.13e-2)" "unprognostic (1.04e-1)" "unprognostic (3.05e-2)" "unprognostic (1.36e-2)" "unprognostic (8.59e-2)" "unprognostic (7.71e-3)" "unprognostic (1.12e-1)" 2.3 3.8 6.2 6.9 6.4 1.1 5.1 8.6 6.0 2.7 1.7 1.1 1.2 2.7 4.2 0.8 6.1 2.6 2.4 7.7 8.4 2.5 2.0 9.9 2.1 17.3 14.8 1.6 0.7 4.5 1.0 4.6 18.9 3.5 1.1 0.5 7.6 7.2 6.5 2.3 0.9 3.5 21.5 11.9 1.4 1.8 17.4 2.0 2.4 2.2 5.3 2.4 0.3 26.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.5 0.2 6.8 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.0 24.5 0.0 0.2 0.2 0.5 0.1 0.0 0.0 0.2 0.1 589.8 0.0 0.0 0.1 0.1 0.0 8.1 0.0 0.2 0.1 16.5 0.0 0.0 0.1 0.1 0.0 0.5 1.0 0.1 0.0 28.6 0.0 7.7 99.6 1.8 264.0 261.2 3.4 0.8 55.9 145.2 94.4 0.7 19.0 122.4 20.8 39.7 449.2 7.1 1.5 232.7 6.2 6.4 8.6 6.0 7.7 8.4 17.3 14.8 18.9 21.5 17.4 26.4 0.8 0.0 0.5 0.7 0.7 0.5 0.0 0.0 0.0 0.0 0.8 3.8 0.4 0.0 0.6 0.0 0.0 0.0 44.3 0.0 0.0 0.0 0.2 0.2 0.1 3.5 0.0 2.1 0.3 0.0 0.0 0.3 0.0 0.0 5.1 0.1 0.7 0.3 4.1 0.0 0.6 0.0 0.0 15.0 28.0 0.3 0.3 43.2 0.0 177.1 50.3 0.1 350.1 2.0 0.4 0.0 0.0 0.0 1.4 0.0 0.0 0.4 0.7 0.2 6.6 0.4 1.3 0.7 0.2 0.0 0.6 0.0 22.6 0.1 0.1 0.0 CYBRD1 "CYB561A2, DCYTB, FLJ23462, FRRS3" ENSG00000071967 "Cytochrome b reductase 1" Q53TN4 2 171522247-171558129 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Electron transport, Transport" "Oxidoreductase, Translocase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 221.2;Fibroblasts: 243.4;Leydig cells: 202.0;Peritubular cells: 221.5;Proximal enterocytes: 689.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "classical monocyte: 17.4;intermediate monocyte: 17.7;myeloid DC: 16.8;neutrophil: 9.8;non-classical monocyte: 13.7" "Group enriched" "Detected in many" 4 "dendritic cells: 16.8;granulocytes: 9.8;monocytes: 17.7" "Cell line enhanced" "Detected in many" "ASC diff: 1064.0;ASC TERT1: 453.8;BJ hTERT+: 408.2;HSkMC: 327.3;hTERT-RPE1: 276.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014757 Approved Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA014757: AB_1847374" "unprognostic (1.35e-1)" "unprognostic (1.57e-1)" "unprognostic (2.89e-2)" "unprognostic (4.87e-2)" "unprognostic (2.97e-2)" "unprognostic (3.11e-2)" "unprognostic (2.86e-1)" "unprognostic (5.44e-3)" "unprognostic (8.90e-3)" "unprognostic (3.57e-3)" "unprognostic (1.74e-1)" "unprognostic (1.71e-1)" "unprognostic (1.02e-3)" "unprognostic (1.93e-2)" "unprognostic (8.48e-2)" "unprognostic (2.77e-2)" "unprognostic (1.51e-2)" 166.7 97.5 32.6 24.4 38.8 18.3 148.7 33.9 34.1 140.0 32.6 68.7 197.7 100.2 49.7 70.6 88.2 153.7 128.6 28.2 45.9 32.0 21.7 129.9 33.8 45.2 38.7 180.9 21.6 12.0 26.1 38.1 40.5 70.6 39.0 22.2 63.7 76.7 23.3 85.0 233.4 87.9 35.6 30.6 53.3 23.8 35.9 27.9 231.0 82.8 30.1 84.3 90.4 43.0 24.8 18.1 10.1 19.2 1064.0 453.8 1.3 88.3 408.2 45.0 56.4 1.1 33.8 0.0 14.8 214.2 46.2 12.2 8.4 7.2 53.2 18.9 2.2 20.7 26.1 0.4 222.7 22.0 1.9 327.3 68.8 70.5 13.7 276.3 29.6 12.4 7.0 0.2 128.3 0.0 7.1 20.4 5.1 0.0 4.6 2.5 125.3 1.5 7.0 1.4 1.3 4.7 104.2 0.2 56.5 3.6 35.8 13.5 59.5 101.0 14.4 96.1 38.3 0.3 0.4 0.2 49.5 18.3 55.6 0.0 17.4 0.8 1.6 17.7 0.3 0.0 0.3 0.2 16.8 0.0 0.0 0.0 9.8 3.6 13.7 0.7 0.0 7.5 32.6 38.8 33.9 34.1 28.2 45.9 45.2 38.7 40.5 35.6 35.9 43.0 37.6 221.2 109.0 45.1 0.9 121.2 47.3 20.3 38.7 0.0 54.7 48.0 18.4 37.1 34.7 25.8 0.0 1.9 3.4 16.1 0.0 1.0 1.5 4.2 35.6 33.9 0.0 85.0 0.9 6.4 2.3 243.4 13.3 8.3 2.5 1.6 73.5 2.4 48.5 0.0 1.5 22.2 2.0 60.7 92.0 6.1 202.0 28.4 44.4 36.5 29.3 27.9 4.1 12.1 54.2 1.8 16.2 221.5 2.2 22.5 689.4 0.3 6.9 1.5 19.7 89.6 49.9 1.2 1.2 7.0 60.1 1.4 5.9 2.8 27.6 18.2 DCHS1 "CDH25, CDHR6, FIB1, FLJ11790, KIAA1773, PCDH16" ENSG00000166341 "Dachsous cadherin-related 1" Q96JQ0 11 6621330-6655809 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 34.8;Endometrial stromal cells: 17.3;Endothelial cells: 29.0;Fibroblasts: 17.0;Granulosa cells: 19.3;Hepatic stellate cells: 61.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 33.5;HUVEC TERT2: 47.1;REH: 23.5;SH-SY5Y: 32.4;TIME: 20.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017970, HPA050246" Approved Approved "Plasma membrane" NA NA 4000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA017970: AB_2669718, HPA050246: AB_2681062" "unprognostic (2.42e-1)" "unprognostic (1.13e-1)" "unprognostic (8.93e-2)" "unprognostic (3.52e-2)" "unprognostic (1.83e-1)" "unprognostic (1.38e-3)" "unprognostic (2.52e-2)" "unprognostic (4.55e-3)" "unprognostic (2.63e-2)" "unprognostic (2.93e-2)" "unprognostic (5.96e-2)" "unprognostic (6.87e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (5.62e-2)" "unprognostic (2.28e-1)" "unprognostic (1.60e-2)" "unprognostic (1.24e-3)" 9.4 2.5 7.4 8.4 6.8 0.7 9.3 6.1 6.3 19.5 0.9 19.0 4.1 28.9 2.4 5.0 13.2 8.3 9.2 6.6 10.1 4.6 2.0 10.1 4.0 7.6 6.3 11.6 3.3 2.0 3.2 10.1 5.7 9.3 3.4 0.6 3.5 11.5 4.2 3.7 8.3 16.2 4.7 12.9 8.2 3.0 8.7 3.8 4.1 4.6 2.2 14.8 9.3 3.8 0.0 0.1 33.5 0.1 0.0 0.1 0.3 1.2 8.7 5.4 6.0 0.3 0.0 0.1 5.1 9.9 0.4 0.0 2.7 0.1 3.7 0.1 0.9 0.7 0.0 0.0 0.3 0.2 0.0 1.0 0.1 2.5 0.0 0.0 47.1 0.1 0.2 0.0 2.0 0.0 1.2 0.6 5.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 2.4 32.4 0.0 0.3 0.2 3.5 0.0 1.3 20.4 0.1 10.0 0.1 0.0 0.1 0.0 0.1 0.3 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 7.4 6.8 6.1 6.3 6.6 10.1 7.6 6.3 5.7 4.7 8.7 3.8 34.8 0.0 0.5 12.1 0.2 2.9 0.3 0.0 0.0 1.5 1.7 3.0 3.8 4.3 0.0 0.0 0.0 0.2 1.4 0.2 0.0 1.0 3.1 0.8 17.3 29.0 0.0 2.7 2.0 0.4 0.3 17.0 1.1 0.7 0.0 19.3 61.1 0.2 2.2 0.0 7.4 0.7 0.0 4.7 4.2 3.4 1.2 2.4 16.0 4.7 0.2 0.9 0.0 10.1 1.4 0.1 0.1 1.9 0.2 0.3 0.1 0.1 0.0 0.5 0.0 7.4 4.9 4.9 0.6 0.5 1.7 0.3 1.2 4.6 1.1 0.1 DENND6B "AFI1B, FAM116B, MGC33692" ENSG00000205593 "DENN domain containing 6B" Q8NEG7 22 50309030-50327012 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 42.1;Late spermatids: 58.7;monocytes: 39.4;Respiratory ciliated cells: 65.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 6.9;RPMI-8226: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018934, HPA021653, HPA029570" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 43: Testis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA018934: AB_1848365, HPA021653: AB_1848366, HPA029570: AB_10602131" "unprognostic (2.50e-2)" "unprognostic (2.55e-2)" "prognostic unfavorable (1.41e-4)" "prognostic favorable (5.93e-5)" "unprognostic (9.39e-2)" "unprognostic (3.17e-1)" "unprognostic (1.89e-3)" "unprognostic (1.16e-1)" "unprognostic (5.10e-2)" "unprognostic (4.50e-2)" "unprognostic (1.19e-2)" "unprognostic (1.18e-1)" "unprognostic (8.92e-2)" "unprognostic (1.10e-1)" "unprognostic (4.15e-1)" "unprognostic (1.56e-1)" "unprognostic (1.31e-2)" 2.4 3.8 10.6 2.3 10.8 1.0 3.4 8.0 14.4 6.2 8.6 3.9 1.1 5.2 2.5 2.5 13.4 3.2 1.7 10.3 9.5 7.6 1.7 4.7 2.9 9.4 9.1 4.0 5.4 2.7 13.6 1.0 9.5 5.5 0.9 4.2 3.6 3.6 0.7 2.6 3.9 1.7 6.9 4.5 3.3 6.7 9.6 0.8 6.7 0.6 1.7 2.6 3.5 7.7 0.5 1.8 3.9 4.3 1.0 3.7 0.0 0.8 1.9 0.5 0.3 0.1 2.8 6.9 1.7 1.9 0.2 3.4 0.1 0.1 0.2 1.7 1.0 1.2 3.5 0.2 0.9 0.2 3.0 3.1 4.2 0.1 0.6 3.8 0.8 0.1 1.5 1.2 0.9 3.0 0.0 0.6 0.3 2.0 0.2 1.0 0.0 10.0 4.9 1.6 1.7 3.1 2.1 2.7 0.3 0.2 4.3 1.0 0.9 0.7 0.6 0.6 0.1 1.0 0.2 1.0 1.7 0.8 0.8 0.2 0.8 0.0 0.1 1.0 0.2 0.2 0.1 0.2 0.5 0.2 0.1 0.2 0.1 0.3 1.3 0.4 0.1 0.3 10.6 10.8 8.0 14.4 10.3 9.5 9.4 9.1 9.5 6.9 9.6 7.7 4.5 3.2 4.1 16.3 14.9 1.1 3.6 6.1 5.7 6.2 5.4 5.8 1.3 11.5 8.3 5.5 22.9 0.3 9.5 3.9 3.9 6.5 24.7 42.1 4.6 5.7 10.2 4.4 20.3 1.8 0.6 4.2 9.2 5.7 5.7 2.8 4.2 1.0 13.7 1.7 13.7 3.3 4.1 24.2 7.8 58.7 2.5 20.0 5.4 2.8 39.4 5.6 5.2 9.0 2.5 2.6 2.1 2.6 33.2 2.4 14.0 17.8 65.5 17.5 0.0 2.5 3.0 24.7 22.2 1.6 0.6 1.0 8.4 3.1 3.6 2.3 DHDDS "DS, FLJ13102, hCIT, HDS, RP59" ENSG00000117682 "Dehydrodolichyl diphosphate synthase subunit" Q86SQ9 1 26432282-26471306 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism" Transferase "Disease variant, Epilepsy, Mental retardation, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 256.5;Early spermatids: 99.1;Rod photoreceptor cells: 106.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026721, HPA026727" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA026721: AB_1847643, HPA026727: AB_1847644" "unprognostic (1.11e-2)" "unprognostic (5.43e-2)" "unprognostic (5.12e-2)" "unprognostic (9.81e-2)" "unprognostic (6.71e-2)" "unprognostic (7.23e-2)" "unprognostic (1.32e-3)" "unprognostic (3.81e-3)" "unprognostic (2.40e-1)" "unprognostic (5.42e-2)" "unprognostic (4.51e-2)" "unprognostic (3.40e-2)" "prognostic favorable (4.08e-7)" "unprognostic (9.42e-2)" "unprognostic (2.85e-1)" "unprognostic (2.22e-1)" "unprognostic (2.95e-1)" 57.3 19.6 12.3 18.9 11.8 12.4 22.7 32.5 14.0 14.6 14.6 37.3 19.1 13.5 38.5 26.3 12.9 15.9 19.8 12.8 13.3 25.5 22.0 13.9 17.6 15.5 16.9 11.4 18.5 39.8 20.9 12.6 18.8 14.1 38.8 37.8 43.3 14.0 13.5 21.2 18.2 18.4 9.0 14.1 23.3 12.3 14.1 14.1 19.1 11.8 20.8 18.1 14.4 12.2 34.2 24.8 20.6 23.8 36.1 28.2 28.4 54.9 33.4 44.0 41.6 37.4 34.6 38.4 33.3 57.2 30.0 24.1 25.4 42.8 42.9 22.7 13.9 38.0 66.9 30.8 39.3 41.4 51.5 40.3 27.6 59.1 32.2 29.4 51.2 26.7 27.3 41.0 39.7 19.4 23.1 20.2 26.3 53.1 36.2 25.3 33.4 31.2 25.4 28.8 24.4 19.4 36.4 38.0 26.6 26.8 29.8 20.9 63.0 30.1 26.3 60.4 32.0 48.1 72.4 39.5 43.0 54.0 26.8 9.4 16.1 9.6 13.8 23.6 9.8 13.2 9.0 9.1 13.6 10.2 7.4 10.9 13.0 10.1 23.1 11.5 8.3 10.5 12.3 11.8 32.5 14.0 12.8 13.3 15.5 16.9 18.8 9.0 14.1 12.2 9.4 9.6 7.8 7.8 13.5 4.6 9.6 12.0 10.8 29.6 9.6 7.4 15.5 15.7 13.8 14.7 256.5 18.3 13.7 76.3 11.7 19.3 99.1 11.6 12.9 11.1 20.9 5.7 26.9 14.5 23.4 11.1 33.6 20.0 19.0 14.4 10.0 13.2 24.5 15.2 28.5 46.3 14.2 11.5 7.1 23.4 10.5 10.5 10.6 10.3 34.4 16.3 14.4 9.0 11.4 17.6 40.3 7.5 18.7 10.6 24.7 29.3 11.5 106.1 0.0 8.4 14.5 13.2 13.5 12.4 5.1 25.4 10.3 15.8 26.0 12.2 DLL1 ENSG00000198719 "Delta like canonical Notch ligand 1" O00548 6 170282206-170306565 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway" "Developmental protein" "Autism spectrum disorder, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 53.9" "Cell type enhanced" "Detected in many" "Adipocytes: 88.8;Basal keratinocytes: 66.9;Basal squamous epithelial cells: 82.0;Enteroendocrine cells: 51.9;Intestinal goblet cells: 80.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "NK-cell: 3.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 3.3" "Cell line enhanced" "Detected in some" "HaCaT: 6.8;HBEC3-KT: 4.5;NB-4: 14.2;THP-1: 14.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA001255 Approved "Plasma membrane" NA NA 690000 "Cluster 48: NK-cells - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA001255: " "unprognostic (1.03e-1)" "unprognostic (9.22e-2)" "unprognostic (2.17e-3)" "unprognostic (1.95e-1)" "unprognostic (2.89e-2)" "unprognostic (6.35e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-1)" "unprognostic (9.22e-2)" "unprognostic (1.14e-2)" "unprognostic (1.39e-2)" "unprognostic (2.64e-2)" "unprognostic (5.23e-3)" "unprognostic (3.50e-1)" "unprognostic (1.83e-1)" "unprognostic (4.33e-2)" "unprognostic (1.66e-1)" 20.9 8.6 2.8 2.1 6.9 0.7 19.2 3.3 4.5 21.1 0.2 15.4 3.9 10.1 0.3 21.9 11.5 0.8 15.9 2.2 2.9 12.5 6.4 13.1 1.9 6.0 5.1 4.2 16.9 0.3 6.2 1.2 4.8 28.7 0.9 0.4 17.7 1.1 5.3 26.2 19.3 0.8 2.0 53.9 10.9 1.6 4.0 0.2 12.4 0.7 0.4 9.6 22.9 11.0 0.7 0.1 3.3 2.0 0.1 0.1 1.5 0.3 0.2 0.2 0.3 1.0 0.1 0.0 0.3 0.1 0.6 6.8 1.4 4.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.6 0.1 0.6 0.0 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.8 0.0 14.2 0.2 0.1 0.0 1.1 2.8 0.0 0.0 0.4 1.6 0.2 0.1 0.0 0.0 1.1 0.4 14.8 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.4 0.0 0.0 0.1 2.8 6.9 3.3 4.5 2.2 2.9 6.0 5.1 4.8 2.0 4.0 11.0 88.8 0.0 0.5 26.1 2.7 66.9 14.9 31.2 82.0 1.4 5.4 14.7 11.8 0.0 7.2 1.8 22.9 3.1 3.0 3.0 0.0 0.3 0.4 5.1 10.1 28.5 51.9 0.4 6.9 1.8 5.9 19.2 1.5 5.3 5.7 0.2 21.4 0.2 1.3 0.0 6.4 80.3 16.2 4.8 6.6 1.9 0.3 2.7 7.2 4.7 0.2 1.1 0.0 28.6 26.7 0.7 2.5 1.2 0.3 4.8 2.5 0.1 9.0 0.6 13.1 12.3 8.2 0.5 2.0 8.5 12.8 3.7 4.7 0.1 3.6 1.1 DNAJB13 "RSPH16A, TSARG6" ENSG00000187726 "DnaJ heat shock protein family (Hsp40) member B13" P59910 11 73951026-73970366 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" Chaperone "Ciliopathy, Disease variant, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 53.2;testis: 18.9" "Group enriched" "Detected in some" 4 "Early spermatids: 90.6;Endometrial ciliated cells: 114.8;Late spermatids: 62.9;Respiratory ciliated cells: 104.2" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.7;Karpas-707: 2.6;RPTEC TERT1: 4.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052465, HPA061330" Enhanced Approved "Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA052465: AB_2681842, HPA061330: AB_2732659" "unprognostic (1.07e-1)" "unprognostic (3.23e-2)" "unprognostic (3.27e-3)" "unprognostic (1.56e-2)" "unprognostic (1.03e-1)" "unprognostic (1.20e-4)" "unprognostic (1.30e-2)" "unprognostic (1.72e-4)" "unprognostic (5.00e-2)" "unprognostic (4.73e-2)" "unprognostic (6.30e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (2.10e-6)" "unprognostic (3.32e-2)" "unprognostic (1.41e-1)" "unprognostic (9.44e-2)" "unprognostic (2.40e-2)" 0.1 0.1 1.5 1.2 1.5 4.4 0.2 1.0 1.4 5.5 12.2 0.1 0.6 2.0 5.2 0.1 53.2 2.2 0.1 2.0 1.9 1.0 0.1 3.1 2.1 4.8 5.7 0.3 0.8 0.1 1.1 0.5 3.6 0.9 0.0 0.4 0.6 2.9 0.3 0.1 2.9 0.1 4.0 1.3 0.2 18.9 2.4 0.0 0.2 0.0 0.0 0.2 0.1 1.8 0.0 0.4 0.3 0.7 0.0 0.1 0.2 0.1 0.0 0.2 0.0 0.7 0.2 0.9 2.1 0.2 0.3 0.5 0.1 0.0 0.0 2.7 0.3 1.0 0.9 0.3 0.0 0.2 0.6 0.0 0.4 0.1 0.0 0.0 0.0 1.4 0.2 2.6 0.4 0.3 0.6 0.9 0.2 0.2 1.5 0.4 1.2 1.1 4.5 0.5 0.3 1.0 0.5 2.2 0.2 0.4 0.3 0.7 0.0 0.0 0.6 0.6 0.0 2.2 2.0 1.9 0.0 0.3 0.1 0.7 0.1 0.2 0.2 0.0 0.0 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.0 0.1 0.0 0.7 0.2 0.1 1.5 1.5 1.0 1.4 2.0 1.9 4.8 5.7 3.6 4.0 2.4 1.8 0.2 3.2 0.0 2.0 0.0 0.0 1.9 11.1 0.0 0.2 0.1 0.3 0.2 0.0 7.6 1.8 0.0 0.1 0.0 0.1 0.0 1.7 90.6 114.8 2.4 0.2 0.0 0.0 0.4 0.0 0.1 0.5 0.0 13.4 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.3 10.2 0.0 0.0 62.9 1.2 0.3 1.8 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 1.2 0.0 1.3 1.4 1.0 104.2 0.9 0.0 1.1 3.3 19.5 1.5 0.0 0.0 0.0 0.3 0.0 0.0 1.2 DUS1L "DUS1, PP3111" ENSG00000169718 "Dihydrouridine synthase 1 like" Q6P1R4 17 82057506-82065887 "Predicted intracellular proteins" "tRNA processing" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023384 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 18: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA023384: AB_1847879" "unprognostic (4.42e-2)" "unprognostic (2.19e-2)" "unprognostic (4.30e-2)" "unprognostic (3.03e-2)" "unprognostic (1.73e-3)" "unprognostic (1.84e-1)" "unprognostic (4.01e-2)" "unprognostic (5.17e-2)" "unprognostic (1.10e-1)" "unprognostic (4.16e-3)" "unprognostic (5.23e-3)" "unprognostic (3.13e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (4.17e-2)" "unprognostic (8.57e-2)" "unprognostic (3.47e-1)" "unprognostic (1.70e-3)" 83.3 86.7 38.2 51.1 38.0 94.2 89.0 35.2 49.7 85.3 40.6 101.3 66.6 74.0 23.0 117.8 81.8 27.0 93.1 38.4 34.9 90.4 174.3 80.5 64.8 40.4 36.4 82.3 148.3 32.0 99.7 27.0 37.0 118.8 29.8 16.9 105.8 30.4 144.3 127.1 107.2 18.9 35.2 131.3 119.4 93.6 38.5 37.7 93.6 27.3 33.3 87.9 85.0 38.6 169.4 109.0 37.7 44.3 28.9 28.4 115.0 57.5 26.8 56.5 40.2 99.7 77.9 133.7 65.3 33.0 39.8 112.0 46.1 60.9 21.9 54.6 263.1 89.2 167.3 178.8 65.3 138.8 101.0 43.1 75.1 37.3 46.4 27.0 64.1 124.8 147.1 69.4 28.5 268.6 192.9 114.9 43.7 87.6 151.7 143.7 43.1 151.7 42.3 114.3 193.9 118.7 45.2 192.6 127.1 35.8 112.3 133.1 49.1 91.7 89.0 79.3 150.1 164.5 48.9 113.0 58.8 102.2 65.0 3.0 3.5 5.0 4.0 3.9 6.0 3.9 4.0 5.0 3.6 3.3 6.5 5.6 1.2 5.9 5.3 7.9 7.6 2.0 38.2 38.0 35.2 49.7 38.4 34.9 40.4 36.4 37.0 35.2 38.5 38.6 36.8 28.9 19.1 17.6 30.0 22.0 20.0 10.0 10.8 28.3 78.3 69.8 21.3 24.3 15.0 11.0 29.2 16.1 60.1 65.2 7.9 12.1 87.2 30.5 28.4 21.0 43.2 21.7 15.9 39.1 19.1 19.1 37.2 37.6 3.8 46.3 13.9 77.8 21.0 18.5 15.8 58.1 8.2 26.8 14.3 146.2 14.3 27.0 10.6 10.3 19.2 17.8 27.8 10.1 18.2 32.0 32.2 13.5 33.7 40.9 32.4 24.5 15.3 47.8 13.1 18.0 23.9 43.3 9.6 23.3 28.4 15.6 28.4 52.2 75.4 37.5 EFNB1 "CFNS, Elk-L, EPLG2, LERK2" ENSG00000090776 "Ephrin B1" P98172 X 68829021-68842160 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Cancer-related genes, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 117.3;Granulosa cells: 134.5;Hepatic stellate cells: 143.5;Suprabasal keratinocytes: 120.5;Theca cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 3.5" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 97.0;hTCEpi: 74.1;PC-3: 70.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB031489, HPA067188" Uncertain Supported "Plasma membrane" NA NA 1300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "CAB031489: AB_631414, HPA067188: AB_2685799" "unprognostic (2.00e-1)" "unprognostic (1.33e-2)" "unprognostic (1.77e-2)" "prognostic unfavorable (3.32e-5)" "unprognostic (1.04e-1)" "unprognostic (2.48e-2)" "unprognostic (8.05e-3)" "unprognostic (2.15e-1)" "prognostic unfavorable (8.68e-4)" "unprognostic (3.94e-2)" "prognostic unfavorable (4.29e-4)" "unprognostic (1.29e-1)" "unprognostic (2.17e-3)" "unprognostic (2.76e-2)" "unprognostic (8.03e-2)" "unprognostic (1.72e-3)" "unprognostic (1.86e-2)" 47.0 23.7 9.3 8.2 9.5 2.3 41.2 8.7 11.8 27.1 8.7 27.6 19.1 19.4 10.7 32.0 19.6 18.3 32.5 9.1 8.9 44.0 11.6 41.6 4.3 9.4 9.1 14.3 7.6 16.5 10.3 25.4 8.9 19.8 13.2 1.2 11.2 16.2 9.1 52.5 20.6 8.8 9.6 26.1 18.1 6.3 9.7 5.6 19.6 9.5 4.8 25.9 27.9 9.3 10.4 5.3 41.9 15.6 21.7 13.4 21.9 8.7 9.5 3.8 2.8 4.8 19.0 2.5 56.7 3.3 5.0 54.3 40.0 97.0 2.1 4.3 10.2 2.6 2.3 8.5 20.0 1.9 21.3 25.0 74.1 9.4 42.4 3.4 29.3 5.3 2.8 0.2 3.3 8.5 4.2 2.0 29.0 63.5 70.9 18.6 4.4 16.6 15.9 36.1 15.6 7.5 6.7 2.0 2.6 31.7 1.6 3.6 49.7 7.2 8.9 19.6 3.3 0.1 2.3 2.5 3.6 11.3 4.7 0.0 0.6 0.3 0.4 1.7 0.3 0.3 0.4 0.4 3.5 0.2 0.3 0.2 0.1 0.7 1.1 0.5 0.2 0.5 9.3 9.5 8.7 11.8 9.1 8.9 9.4 9.1 8.9 9.6 9.7 9.3 81.1 3.2 1.1 2.6 3.2 117.3 66.2 60.7 93.4 3.3 3.6 11.2 8.2 20.0 12.8 22.0 0.0 11.4 5.9 59.4 0.0 16.4 0.4 2.6 7.6 42.4 8.4 2.7 1.0 15.6 75.9 20.5 21.4 4.5 4.5 134.5 143.5 4.8 12.4 1.7 1.0 27.6 8.2 9.1 23.8 1.3 27.4 8.6 21.4 2.8 5.9 12.5 2.1 0.5 0.6 46.3 52.6 8.2 2.3 40.2 28.6 5.7 2.8 1.3 13.1 8.7 12.5 2.0 3.8 76.2 120.5 11.2 4.7 116.2 29.8 93.6 EHD1 "FLJ42622, FLJ44618, H-PAST, HPAST1, PAST1" ENSG00000110047 "EH domain containing 1" Q9H4M9 11 64851642-64888296 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 151.6;testis: 159.9" "Group enriched" "Detected in all" 10 "Early spermatids: 1033.0;Late spermatids: 1950.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751, HPA067747" Approved Supported "Plasma membrane" NA NA 10000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713, HPA067747: AB_2685896" "unprognostic (1.51e-1)" "unprognostic (3.21e-1)" "unprognostic (6.35e-3)" "unprognostic (2.43e-1)" "unprognostic (1.62e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (2.81e-5)" "unprognostic (1.46e-3)" "unprognostic (9.10e-3)" "unprognostic (9.44e-2)" "unprognostic (2.11e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (6.37e-2)" "unprognostic (9.88e-2)" "unprognostic (2.74e-1)" "unprognostic (2.59e-2)" 39.7 25.4 21.5 59.7 26.6 151.6 21.8 38.6 32.6 26.2 18.2 32.3 33.8 28.1 8.4 26.0 27.0 25.0 39.3 24.9 26.8 31.2 22.0 44.7 65.6 32.7 28.2 13.6 11.1 8.9 7.0 35.4 29.9 18.8 14.5 3.0 16.6 20.9 32.1 34.4 38.5 28.3 31.0 74.4 29.3 159.9 30.5 28.9 19.3 31.5 50.3 55.3 23.0 33.4 109.4 74.1 26.2 28.9 31.2 50.2 15.4 108.2 97.4 89.5 51.8 96.5 66.2 142.0 37.8 129.9 76.5 86.6 27.3 108.9 34.5 89.5 15.2 94.8 37.1 49.1 36.8 30.9 24.6 22.8 22.9 138.7 43.2 40.6 89.8 27.6 39.6 243.8 68.7 57.8 62.5 51.4 17.5 27.5 95.9 24.8 83.5 49.9 84.5 35.7 18.6 16.6 60.8 109.3 48.6 29.5 149.2 21.8 127.9 39.6 35.4 106.0 52.6 100.2 48.5 112.1 103.3 40.1 22.0 18.0 13.9 99.6 39.0 16.1 39.2 24.0 27.3 33.8 7.2 18.2 16.2 23.1 57.1 25.4 33.7 8.7 31.8 30.7 21.5 26.6 38.6 32.6 24.9 26.8 32.7 28.2 29.9 31.0 30.5 33.4 31.2 76.9 30.3 4.2 46.0 67.3 52.8 39.4 17.6 3.8 28.8 24.8 29.2 18.6 22.9 14.7 2.1 88.6 76.5 75.9 7.9 29.4 1033.0 41.9 24.4 29.3 6.6 19.8 1.7 40.8 24.5 32.4 25.5 54.9 93.8 37.2 10.4 10.9 32.2 5.0 3.5 27.7 12.2 37.4 61.0 1950.6 30.1 79.6 26.6 1.9 34.3 5.9 78.2 2.5 12.2 101.5 47.7 27.1 50.8 28.2 38.9 41.9 16.5 2.8 78.9 47.9 53.5 55.0 27.4 19.9 49.2 137.0 71.7 19.8 22.1 42.7 EHD2 PAST2 ENSG00000024422 "EH domain containing 2" Q9NZN4 19 47713422-47743134 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 161.9;Leydig cells: 99.1;Peritubular cells: 107.2;Sertoli cells: 236.7;Smooth muscle cells: 139.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 312.2;BJ: 238.5;fHDF/TERT166: 258.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047394, HPA049890, HPA049986, HPA066751" Approved Supported "Plasma membrane" NA NA 1500000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA047394: AB_2680026, HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (1.50e-1)" "unprognostic (2.11e-2)" "unprognostic (3.16e-3)" "unprognostic (1.54e-1)" "unprognostic (3.33e-2)" "unprognostic (5.42e-3)" "unprognostic (3.36e-2)" "unprognostic (1.33e-2)" "unprognostic (2.70e-3)" "prognostic unfavorable (8.75e-4)" "unprognostic (5.49e-3)" "unprognostic (9.50e-2)" "prognostic unfavorable (3.98e-4)" "unprognostic (6.59e-3)" "unprognostic (6.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.06e-3)" 195.0 59.9 18.4 32.8 17.6 0.4 133.9 16.5 21.2 110.3 11.9 116.1 14.3 119.9 13.2 53.5 75.4 31.2 85.9 15.9 17.1 24.4 14.4 102.8 9.1 23.3 19.3 68.3 28.2 6.2 12.6 50.3 20.0 62.2 14.7 3.0 34.2 51.1 39.6 54.7 54.5 79.6 17.2 40.3 56.3 11.2 24.1 5.1 49.5 28.2 8.3 112.3 88.8 15.8 62.7 142.7 0.1 1.7 312.2 236.0 0.2 238.5 114.0 86.0 70.0 9.3 31.2 0.0 0.3 258.6 20.3 78.1 1.5 126.5 51.9 0.1 0.8 8.4 78.4 0.7 197.0 0.0 16.6 230.1 109.5 72.5 70.6 113.7 168.4 0.7 26.6 0.2 91.7 11.4 13.3 0.7 1.8 9.2 25.9 1.4 10.0 0.2 69.5 2.9 0.1 0.8 212.5 8.2 6.2 19.1 20.2 4.3 192.6 128.0 27.8 112.5 52.2 0.2 0.2 0.2 119.3 3.3 27.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 18.4 17.6 16.5 21.2 15.9 17.1 23.3 19.3 20.0 17.2 24.1 15.8 161.9 60.9 20.6 10.7 0.3 20.3 29.4 31.0 12.5 5.5 7.3 10.8 11.6 10.0 22.5 5.5 0.0 1.1 0.8 0.1 0.0 21.2 0.6 3.4 60.5 75.4 0.0 8.6 4.0 14.1 1.6 55.8 5.1 4.5 2.5 24.7 48.9 3.1 1.9 0.0 0.9 0.0 2.0 1.3 8.8 4.3 99.1 1.6 8.8 7.5 0.6 1.8 0.0 3.5 0.3 31.1 0.0 107.2 0.1 28.8 0.0 0.1 5.5 0.8 236.7 24.8 139.4 0.9 3.0 15.8 13.5 1.5 1.5 27.2 0.0 33.4 EHD3 PAST3 ENSG00000013016 "EH domain containing 3" Q9NZN3 2 31234152-31269451 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 38.7;esophagus: 43.9" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 24.3;Hepatic stellate cells: 120.3;Syncytiotrophoblasts: 43.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "memory B-cell: 20.8;naive B-cell: 5.6" "Lineage enriched" "Detected in many" 7 "B-cells: 20.8" "Cell line enhanced" "Detected in many" "BJ: 79.7;BJ hTERT+: 192.2;HEL: 77.4;U-266/70: 48.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA066751" Approved Approved "Plasma membrane" NA NA 15000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA066751: AB_2685713" "unprognostic (3.44e-1)" "unprognostic (8.88e-2)" "unprognostic (2.21e-1)" "unprognostic (3.79e-2)" "unprognostic (3.70e-2)" "unprognostic (1.89e-1)" "unprognostic (5.49e-2)" "unprognostic (1.21e-1)" "unprognostic (3.74e-2)" "unprognostic (9.72e-2)" "unprognostic (9.92e-3)" "unprognostic (1.06e-1)" "prognostic unfavorable (1.02e-4)" "unprognostic (4.88e-3)" "unprognostic (9.41e-2)" "unprognostic (4.79e-3)" "unprognostic (4.92e-3)" 2.5 9.1 20.5 5.9 29.5 1.9 3.2 10.5 38.7 5.5 1.1 2.5 1.6 4.4 3.0 43.9 4.5 3.4 15.9 29.5 18.5 20.0 11.0 5.7 6.8 11.7 17.8 2.5 1.3 21.1 9.1 11.7 13.9 5.5 1.7 9.0 5.9 4.4 2.3 3.1 3.7 4.6 9.6 7.3 2.2 1.3 31.1 2.7 3.2 5.1 11.1 6.6 6.0 26.2 1.8 8.4 4.5 3.9 7.5 11.3 0.7 79.7 192.2 7.5 6.9 0.0 0.9 0.6 2.9 26.0 6.5 0.8 0.2 5.2 5.3 3.2 7.1 77.4 0.4 0.0 25.7 0.0 0.2 18.1 2.3 7.3 3.0 20.0 0.1 0.2 0.3 0.4 5.6 12.6 1.0 0.1 17.7 0.0 4.3 2.8 0.3 1.8 5.8 8.9 2.2 12.1 0.8 1.3 0.0 14.1 1.2 0.0 0.0 5.8 5.4 0.3 6.5 48.7 6.5 0.1 14.8 0.0 12.4 0.6 0.5 0.5 2.1 1.0 1.1 20.8 1.0 1.4 0.5 5.6 0.9 0.5 1.2 0.8 2.8 0.0 0.5 10.2 20.5 29.5 10.5 38.7 29.5 18.5 11.7 17.8 13.9 9.6 31.1 26.2 1.9 0.0 0.0 2.6 16.2 0.8 1.8 1.7 10.2 9.7 0.6 6.2 24.3 5.7 0.9 0.0 0.0 4.1 0.6 0.0 0.0 0.5 0.1 0.7 2.3 8.4 1.8 6.1 17.1 0.2 8.4 3.3 1.1 0.5 0.0 0.4 120.3 5.0 1.7 0.0 11.1 0.1 0.0 16.1 0.4 0.0 1.2 5.9 0.0 4.7 1.1 9.0 0.0 22.6 5.4 0.2 0.1 3.0 5.8 2.6 0.0 0.2 0.4 5.9 19.7 3.0 7.0 0.6 2.7 10.7 0.9 43.9 1.4 0.7 0.1 4.7 EHD4 PAST4 ENSG00000103966 "EH domain containing 4" Q9H223 15 41895933-41972557 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 189.5;Urothelial cells: 200.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 103.8;TIME: 172.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049890, HPA049986, HPA052729, HPA066751" Approved Approved "Plasma membrane" NA NA 440000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "HPA049890: AB_2680936, HPA049986: AB_2680983, HPA052729: AB_2681928, HPA066751: AB_2685713" "unprognostic (1.45e-1)" "unprognostic (1.37e-1)" "unprognostic (4.34e-3)" "unprognostic (3.36e-2)" "unprognostic (3.46e-2)" "unprognostic (4.48e-3)" "unprognostic (1.52e-1)" "unprognostic (3.36e-3)" "unprognostic (2.25e-1)" "unprognostic (3.74e-1)" "unprognostic (6.93e-2)" "unprognostic (2.35e-1)" "unprognostic (5.05e-2)" "unprognostic (3.49e-2)" "unprognostic (3.19e-2)" "unprognostic (8.27e-2)" "unprognostic (2.72e-1)" 21.6 4.6 3.1 11.8 3.2 10.9 16.4 7.5 3.5 9.4 5.3 12.1 5.5 9.6 10.5 15.0 9.8 15.2 27.8 3.3 3.8 14.3 9.6 15.0 12.8 4.8 4.0 5.6 14.3 12.8 5.8 8.3 4.8 9.5 10.2 6.1 10.4 9.7 4.4 14.3 12.4 12.9 5.2 7.4 9.9 2.8 4.0 5.3 18.4 4.7 8.8 23.8 9.0 6.6 28.7 9.8 9.3 9.6 4.6 6.5 8.1 14.9 31.4 25.9 36.1 41.4 16.1 5.9 39.2 18.8 51.6 28.4 13.9 32.6 19.0 35.7 11.7 8.7 13.5 7.1 11.3 4.0 24.4 5.5 12.6 26.3 28.8 9.9 103.8 8.7 9.2 6.6 21.1 12.2 4.2 4.5 7.1 27.8 33.5 0.1 24.5 9.4 23.4 57.0 15.4 6.5 10.9 23.2 17.0 9.0 22.9 5.6 172.8 8.1 15.7 30.5 73.1 18.1 30.9 12.4 10.3 9.4 71.6 1.1 14.0 9.0 4.0 12.4 6.1 2.1 6.2 5.0 14.9 2.6 2.6 3.8 2.3 4.4 5.2 2.5 7.9 8.0 3.1 3.2 7.5 3.5 3.3 3.8 4.8 4.0 4.8 5.2 4.0 6.6 94.9 6.4 44.2 3.9 20.0 81.6 189.5 68.1 34.1 4.9 31.4 20.1 36.6 30.0 69.0 44.1 31.3 10.1 22.2 96.0 7.9 71.3 16.1 66.1 9.7 114.9 22.6 5.7 1.2 62.6 20.4 21.3 25.5 72.4 61.6 16.2 54.7 8.7 89.0 1.7 0.7 22.5 28.5 35.6 52.7 34.7 7.5 46.3 19.6 12.2 53.5 37.5 4.1 26.7 2.7 75.1 70.9 4.9 31.5 49.9 71.4 4.6 60.8 27.8 13.1 8.0 29.0 5.4 8.2 29.3 79.8 17.4 27.8 21.2 37.3 200.1 ELAPOR1 "EIG121, KIAA1324, maba1" ENSG00000116299 "Endosome-lysosome associated apoptosis and autophagy regulator 1" Q6UXG2 1 109113679-109206781 "Predicted intracellular proteins, Predicted membrane proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 156.7;salivary gland: 166.1;stomach 1: 88.2" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;dendritic cells: 1.2;Hofbauer cells: 1.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 7 "neutrophil: 65.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 65.2" "Cell line enhanced" "Detected in some" "MCF7: 20.8;SCLC-21H: 16.8;SK-BR-3: 17.6;T-47d: 59.1;U-87 MG: 12.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA029869, HPA070749" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "HPA029869: AB_10794320, HPA070749: AB_2686304" "unprognostic (2.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.99e-2)" "prognostic favorable (2.14e-7)" "unprognostic (4.18e-3)" "unprognostic (5.63e-2)" "unprognostic (1.96e-3)" "prognostic favorable (5.69e-5)" "unprognostic (2.79e-2)" "prognostic favorable (2.16e-4)" "unprognostic (3.50e-3)" "unprognostic (1.01e-1)" "unprognostic (2.22e-16)" "unprognostic (2.46e-1)" "unprognostic (1.75e-1)" "unprognostic (5.64e-2)" "unprognostic (8.02e-2)" 0.8 3.2 3.6 4.1 4.4 0.5 56.7 0.0 4.9 70.1 0.0 28.3 45.5 12.8 9.7 1.6 23.9 5.6 0.2 4.4 13.2 0.1 0.2 5.1 2.5 0.2 0.1 0.1 156.7 9.2 32.9 0.2 0.7 48.6 27.8 0.4 166.1 0.3 0.0 3.9 35.3 1.1 0.0 0.8 88.2 18.3 10.0 0.8 9.0 0.1 1.9 0.4 0.1 1.7 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.8 0.5 0.2 0.1 0.2 0.0 0.0 0.5 0.6 0.7 1.3 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 1.1 1.0 0.0 0.0 0.5 20.8 0.2 0.3 0.5 0.0 0.1 0.1 0.3 1.1 0.1 0.0 16.8 0.4 0.1 17.6 0.0 0.1 59.1 0.0 0.4 0.0 2.1 0.2 0.2 1.3 3.6 0.0 12.4 0.0 0.1 0.0 0.1 0.0 4.6 0.0 7.6 0.4 7.5 3.2 0.0 0.1 3.3 1.5 65.2 0.5 0.0 0.0 9.8 2.2 3.6 4.4 0.0 4.9 4.4 13.2 0.2 0.1 0.7 0.0 10.0 1.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.8 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.0 0.0 ELN "SVAS, WBS, WS" ENSG00000049540 Elastin P15502 7 74027789-74069907 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 70.4;Fibroblasts: 115.9;Leydig cells: 110.6;Peritubular cells: 148.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 97.6;BJ: 143.7;fHDF/TERT166: 205.6;U-2197: 817.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010750, HPA018111, HPA056941" Supported Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 2900000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB010750: AB_476930, HPA018111: AB_1848109, HPA056941: AB_2683280" "unprognostic (1.51e-2)" "unprognostic (4.86e-2)" "unprognostic (2.50e-2)" "unprognostic (1.11e-1)" "unprognostic (1.57e-2)" "unprognostic (2.72e-2)" "unprognostic (3.70e-3)" "unprognostic (1.23e-1)" "unprognostic (3.33e-2)" "unprognostic (2.00e-3)" "unprognostic (2.88e-1)" "unprognostic (1.09e-1)" "unprognostic (2.18e-3)" "unprognostic (1.79e-2)" "unprognostic (3.90e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (1.62e-3)" 147.2 21.6 11.6 40.8 14.3 0.1 94.2 19.9 17.6 100.2 24.3 57.6 8.8 73.6 18.4 53.0 70.7 76.7 184.1 13.1 15.3 12.8 13.4 214.1 14.5 15.4 20.1 37.0 90.9 2.8 24.9 58.9 13.8 106.4 11.3 2.8 66.9 35.1 17.9 91.3 40.6 90.0 14.9 40.9 63.2 13.1 14.0 5.1 48.4 16.9 4.5 85.3 84.3 17.9 0.0 2.0 0.8 0.0 97.6 0.6 0.6 143.7 0.1 0.0 0.0 0.6 0.1 0.0 0.0 205.6 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.7 0.5 0.1 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.9 0.0 0.6 0.6 8.3 0.8 0.8 0.4 58.0 1.0 0.0 0.0 28.0 68.9 0.0 1.2 0.1 10.0 0.6 0.0 0.0 0.2 0.3 817.9 0.0 0.2 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 11.6 14.3 19.9 17.6 13.1 15.3 15.4 20.1 13.8 14.9 14.0 17.9 34.6 0.0 6.4 34.9 0.1 11.0 13.5 33.9 4.0 2.8 0.9 1.1 9.7 2.8 4.3 7.3 2.1 0.1 0.3 0.2 0.0 0.3 3.5 3.5 70.4 28.4 1.8 0.0 4.6 3.9 0.3 115.9 7.1 2.3 0.0 0.2 47.2 4.2 0.5 6.7 8.1 1.3 0.0 0.6 20.4 7.5 110.6 1.2 14.2 23.4 0.0 15.9 0.0 14.1 18.5 1.1 0.2 148.2 0.4 1.4 0.0 0.1 3.0 0.8 0.0 12.2 34.1 1.1 1.2 2.1 10.9 0.1 1.2 0.6 0.2 1.1 ENC1 "ENC-1, KLHL37, NRPB, PIG10, TP53I10" ENSG00000171617 "Ectodermal-neural cortex 1" O14682 5 74627406-74641424 "Cancer-related genes, Predicted intracellular proteins" "Actin-binding, Developmental protein" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "brain: 197.3" "Cell type enhanced" "Detected in many" "Excitatory neurons: 271.6;Theca cells: 210.4" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 51 "amygdala: 61.3;basal ganglia: 114.2;cerebral cortex: 190.0;hippocampal formation: 197.3;white matter: 68.6" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebral cortex: 263.2" HPA078061 Uncertain "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA078061: " "prognostic unfavorable (3.88e-4)" "unprognostic (4.90e-2)" "unprognostic (1.13e-1)" "unprognostic (3.00e-3)" "unprognostic (1.05e-1)" "unprognostic (2.22e-3)" "unprognostic (1.36e-1)" "unprognostic (9.74e-2)" "unprognostic (1.24e-1)" "unprognostic (2.59e-1)" "unprognostic (4.98e-2)" "unprognostic (8.08e-2)" "prognostic unfavorable (2.95e-5)" "unprognostic (9.69e-2)" "unprognostic (3.08e-1)" "unprognostic (2.88e-1)" "unprognostic (5.65e-2)" 5.5 2.0 61.3 13.5 114.2 18.0 4.3 0.0 190.0 9.9 0.0 14.7 17.9 6.9 3.8 5.7 2.4 19.2 8.2 197.3 0.0 5.7 18.8 12.7 5.8 0.0 0.0 15.0 32.8 24.7 6.8 11.4 2.4 11.8 21.2 2.3 15.6 19.3 4.7 4.3 21.6 7.6 1.0 11.4 27.0 12.0 0.0 7.1 2.7 3.8 5.0 20.3 3.1 68.6 40.0 47.9 45.8 22.1 20.1 4.5 109.6 27.7 27.6 27.8 19.9 74.0 60.0 0.0 30.9 21.5 46.0 29.9 0.7 46.7 60.0 0.8 3.4 43.6 9.5 36.8 1.9 4.9 0.4 7.6 3.3 72.3 7.3 102.2 23.2 9.5 9.9 23.4 81.5 10.4 4.2 6.4 51.2 39.1 40.4 4.8 31.0 4.0 17.3 27.5 60.3 26.9 4.5 20.5 2.4 58.3 9.7 6.6 59.2 46.3 75.3 30.4 87.7 0.5 0.1 0.8 53.8 4.0 73.9 0.0 2.7 2.6 1.2 2.3 0.0 0.0 0.2 1.4 1.2 0.1 0.1 1.3 0.6 1.4 0.6 0.0 0.0 0.8 61.3 114.2 0.0 190.0 197.3 0.0 0.0 0.0 2.4 1.0 0.0 68.6 10.6 0.0 17.0 18.9 11.7 2.5 14.0 20.2 1.2 1.1 9.1 14.7 2.3 17.2 22.6 11.0 2.1 14.6 51.9 15.3 3.9 69.6 16.2 12.8 7.0 13.9 15.5 0.4 271.6 31.7 5.7 40.4 31.6 11.0 21.5 26.4 41.4 18.0 26.5 0.0 25.4 20.9 57.0 8.2 4.9 20.4 37.6 10.2 0.0 25.3 6.2 0.6 0.0 20.6 15.7 67.0 10.1 33.4 23.2 17.6 12.3 4.4 12.9 1.2 6.6 4.4 41.9 0.5 1.0 3.2 1.1 2.6 15.9 210.4 33.4 18.3 ENOX1 "cCNOX, CNOX, FLJ10094, PIG38" ENSG00000120658 "Ecto-NOX disulfide-thiol exchanger 1" Q8TC92 13 43213518-43786908 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.1" "Cell type enhanced" "Detected in many" "Astrocytes: 173.3;Early spermatids: 190.8;Excitatory neurons: 452.3;Inhibitory neurons: 692.0;Late spermatids: 264.8;Oligodendrocyte precursor cells: 167.9;Oligodendrocytes: 771.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 17.3;RH-30: 24.1;TIME: 17.8;U-2197: 17.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038355 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA038355: AB_10673171" "unprognostic (9.64e-2)" "unprognostic (3.38e-3)" "unprognostic (1.64e-1)" "unprognostic (1.20e-3)" "unprognostic (1.06e-1)" "unprognostic (2.69e-1)" "unprognostic (2.88e-1)" "unprognostic (6.72e-3)" "unprognostic (2.60e-1)" "unprognostic (2.29e-3)" "unprognostic (1.32e-1)" "unprognostic (9.93e-2)" "unprognostic (1.32e-3)" "unprognostic (1.07e-2)" "unprognostic (1.48e-1)" "unprognostic (2.08e-3)" "unprognostic (1.42e-2)" 3.4 1.0 7.8 2.5 12.5 0.3 1.8 4.6 9.2 3.3 0.4 8.5 0.6 5.0 0.9 1.0 2.7 1.6 4.7 7.7 7.9 3.5 0.4 0.9 2.2 10.0 6.9 6.4 1.3 0.7 1.9 4.4 10.3 3.0 1.5 2.0 0.4 3.7 8.1 0.5 1.4 4.2 7.4 0.7 2.3 9.0 8.9 2.8 0.4 0.7 1.4 3.1 2.1 14.1 0.2 0.3 3.4 0.0 3.4 13.2 0.7 1.6 3.8 5.7 5.4 2.4 0.4 0.0 0.2 5.1 0.6 0.1 0.7 0.4 2.5 4.2 5.6 0.7 4.0 0.1 2.1 0.1 0.9 12.7 1.2 17.3 8.7 0.9 0.4 2.8 0.0 0.8 3.5 0.3 5.9 0.2 3.8 0.1 1.5 0.0 24.1 0.0 3.0 0.7 11.8 4.5 2.1 3.5 0.9 2.6 0.7 0.1 17.8 1.9 0.6 17.9 1.9 0.0 0.1 0.1 8.3 0.0 12.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 12.5 4.6 9.2 7.7 7.9 10.0 6.9 10.3 7.4 8.9 14.1 1.5 3.2 0.0 173.3 0.0 0.6 1.3 0.0 2.2 4.3 1.2 0.6 3.0 0.0 2.5 0.0 0.0 0.1 0.0 0.1 5.9 0.6 190.8 0.1 1.9 0.4 0.0 0.0 452.3 0.4 0.0 2.5 0.0 0.1 0.0 2.3 0.0 0.0 0.2 1.7 692.0 0.0 0.0 0.0 1.8 264.8 12.2 0.4 0.0 15.0 0.0 0.3 0.0 167.9 771.1 0.1 0.0 4.5 0.0 2.7 0.0 1.1 5.3 0.4 6.6 6.1 5.1 3.8 7.3 0.3 0.3 0.3 0.1 12.3 0.0 0.5 EPB41L1 "4.1N, KIAA0338" ENSG00000088367 "Erythrocyte membrane protein band 4.1 like 1" Q9H4G0 20 36091504-36232799 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 156.4;Inhibitory neurons: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 1.0" "Lineage enriched" "Detected in single" 10 "dendritic cells: 1.0" "Cell line enhanced" "Detected in many" "A549: 163.5;HaCaT: 237.9;OE19: 192.9;SK-BR-3: 185.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054104, HPA056817" Enhanced Supported "Plasma membrane" NA NA 33000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "HPA054104: AB_2682380, HPA056817: AB_2683244" "unprognostic (2.01e-2)" "unprognostic (7.77e-2)" "unprognostic (1.76e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.19e-1)" "unprognostic (2.31e-1)" "unprognostic (1.23e-1)" "unprognostic (1.56e-2)" "unprognostic (3.87e-1)" "unprognostic (5.83e-3)" "prognostic unfavorable (9.30e-4)" "unprognostic (1.78e-1)" "prognostic favorable (4.39e-10)" "unprognostic (1.25e-1)" "unprognostic (1.71e-1)" "unprognostic (2.47e-1)" "unprognostic (2.26e-2)" 55.1 122.1 68.6 8.1 73.8 0.4 25.7 66.0 97.2 37.7 0.0 31.2 13.8 27.9 31.0 46.3 45.3 40.3 21.3 64.7 81.7 64.7 8.9 30.1 4.4 101.5 80.3 41.8 29.3 37.0 21.1 21.8 94.0 26.9 20.9 39.5 56.6 42.6 12.0 14.2 16.7 27.2 53.0 8.1 64.2 18.3 75.0 4.5 24.8 15.4 14.0 40.7 31.7 79.9 53.5 163.5 57.7 21.5 36.8 22.8 53.8 16.8 37.7 35.1 27.9 108.7 93.7 3.0 26.4 52.7 71.7 237.9 26.7 19.6 26.2 0.5 14.9 0.4 52.7 107.6 11.3 0.2 19.4 19.9 9.4 32.9 2.7 44.7 8.6 13.0 2.7 41.5 30.5 34.2 1.8 0.9 21.4 192.9 49.9 2.6 16.0 66.3 30.5 84.6 20.1 24.5 74.9 185.6 6.4 43.9 45.8 2.4 7.3 40.9 43.0 20.8 3.7 50.3 19.0 0.6 71.2 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 68.6 73.8 66.0 97.2 64.7 81.7 101.5 80.3 94.0 53.0 75.0 79.9 14.5 16.0 22.1 27.7 0.4 2.9 5.0 11.1 30.7 31.9 12.8 9.4 8.5 28.6 16.5 47.8 156.4 1.5 0.8 23.8 19.6 22.2 2.9 10.6 8.7 9.2 15.5 0.0 56.8 10.8 0.5 11.0 50.4 7.5 52.5 13.3 10.0 3.7 6.9 32.0 75.7 6.0 4.1 1.3 2.2 2.7 15.8 6.0 3.6 3.7 0.0 22.7 0.0 24.6 73.1 31.6 15.7 42.2 2.1 5.1 8.0 37.1 21.9 8.7 32.9 6.8 35.1 4.6 7.1 43.2 1.7 1.1 0.8 7.1 13.2 18.0 EPB41L5 "BE37, FLJ12957, KIAA1548, LULU, LULU1, YMO1, YRT" ENSG00000115109 "Erythrocyte membrane protein band 4.1 like 5" Q9HCM4 2 120013077-120179119 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 218.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 55.5;MCF7: 83.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037563, HPA037564" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA037563: AB_2675546, HPA037564: AB_2675547" "unprognostic (1.27e-2)" "unprognostic (2.15e-1)" "unprognostic (2.56e-2)" "unprognostic (2.31e-1)" "unprognostic (3.33e-2)" "unprognostic (1.47e-2)" "unprognostic (1.53e-1)" "unprognostic (9.06e-3)" "unprognostic (5.93e-2)" "unprognostic (8.76e-2)" "unprognostic (2.20e-2)" "unprognostic (9.51e-2)" "prognostic favorable (2.28e-6)" "unprognostic (1.99e-1)" "unprognostic (3.88e-1)" "unprognostic (9.59e-2)" "unprognostic (2.61e-1)" 5.7 6.0 9.0 3.0 7.3 1.0 15.7 43.4 10.6 7.2 4.5 9.9 14.0 7.5 5.8 8.8 12.8 7.4 6.3 7.1 11.1 32.7 56.8 29.9 2.5 8.9 11.1 11.6 26.2 25.1 8.2 9.8 9.0 12.4 8.8 27.8 15.3 6.1 10.1 8.3 11.7 6.5 8.7 2.5 9.1 30.5 12.4 3.6 32.9 8.9 6.6 6.1 8.4 8.1 18.0 6.1 23.8 18.5 16.4 11.8 20.8 3.8 3.7 7.8 7.0 55.5 11.7 0.3 12.9 4.8 9.7 12.1 32.4 14.9 11.5 3.6 10.1 5.2 2.8 31.1 19.1 2.3 5.3 10.6 27.6 14.6 10.4 6.7 22.1 10.4 12.4 1.3 15.6 83.4 4.3 7.9 21.5 8.3 5.6 0.0 7.1 5.0 24.2 17.1 12.3 23.5 16.5 29.0 8.2 32.5 14.0 4.3 18.4 0.7 11.2 12.3 3.9 1.9 3.5 9.2 2.0 0.1 4.5 0.1 0.5 0.6 0.4 0.1 0.1 1.7 0.4 0.4 0.1 1.3 1.1 0.8 0.7 0.6 0.3 0.0 0.2 0.4 9.0 7.3 43.4 10.6 7.1 11.1 8.9 11.1 9.0 8.7 12.4 8.1 6.0 218.0 41.9 61.0 11.1 24.5 28.9 9.7 21.6 33.9 28.0 14.1 13.2 24.3 22.5 33.1 25.0 14.9 4.3 20.6 21.5 18.8 38.0 25.8 12.6 6.8 15.5 5.7 68.4 22.3 12.1 13.1 56.1 45.8 0.0 12.0 17.9 54.2 3.2 8.4 79.8 12.7 22.4 2.1 6.8 20.6 9.0 2.8 14.2 26.2 1.1 15.8 0.0 89.5 25.9 23.2 21.7 9.4 5.9 29.1 20.9 29.0 17.5 35.7 19.7 11.7 9.8 43.5 48.6 18.3 21.7 26.4 6.2 5.7 12.9 39.4 EPCAM "17-1A, 323/A3, CD326, CO-17A, EGP-2, EGP34, EGP40, Ep-CAM, ESA, GA733-2, HEA125, KS1/4, KSA, Ly74, M4S1, MH99, MIC18, MK-1, MOC31, TACST-1, TACSTD1, TROP1" ENSG00000119888 "Epithelial cell adhesion molecule" P16422 2 47345158-47387601 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Tumor antigen" "Cancer-related genes, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 806.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 2317.0;Ductal cells: 999.6;Intestinal goblet cells: 1378.2;Paneth cells: 2437.0;Proximal enterocytes: 2681.1;Undifferentiated cells: 1607.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 538.9;CACO-2: 680.9;CAPAN-2: 944.4;OE19: 911.8;RPTEC TERT1: 398.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB003809, HPA026761, CAB030012, CAB055098, HPA067463" Enhanced Supported "Plasma membrane" NA NA 22000 "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB003809: AB_562285, CAB030012: AB_756075, CAB055098: AB_2335685, HPA026761: AB_1848198, HPA067463: AB_2685846" "unprognostic (6.79e-2)" "unprognostic (2.28e-1)" "unprognostic (1.59e-2)" "unprognostic (1.16e-2)" "unprognostic (1.61e-1)" "unprognostic (3.49e-2)" "unprognostic (2.01e-1)" "unprognostic (3.61e-2)" "unprognostic (3.40e-1)" "prognostic favorable (3.30e-4)" "unprognostic (5.27e-2)" "unprognostic (3.28e-2)" "prognostic favorable (1.04e-6)" "unprognostic (6.38e-3)" "unprognostic (1.28e-1)" "unprognostic (6.45e-3)" "unprognostic (6.08e-2)" 4.4 12.2 3.1 77.0 4.0 10.2 99.7 1.5 3.1 116.2 1.0 806.0 726.5 33.0 238.9 10.8 114.3 71.1 0.6 3.3 9.2 223.1 3.1 74.7 0.9 2.8 3.2 1.2 125.4 219.5 86.9 1.7 3.4 60.5 751.0 0.6 119.8 52.8 0.1 8.8 769.6 22.2 2.6 1.4 172.4 21.7 10.4 6.4 286.8 0.1 2.8 30.9 4.2 2.6 538.9 5.4 0.4 1.2 0.0 0.0 321.3 0.2 0.0 0.6 0.0 680.9 944.4 0.1 141.5 1.0 0.4 247.3 4.6 62.2 2.0 0.1 56.3 0.3 2.5 261.6 0.1 0.3 0.4 0.0 17.6 0.0 0.0 0.0 0.8 0.0 160.9 0.0 0.3 269.7 0.5 24.0 164.3 911.8 31.4 0.3 0.0 136.9 398.6 231.3 354.0 3.2 4.3 187.7 0.6 132.7 158.3 1.0 0.7 0.3 6.3 2.0 1.1 39.2 0.6 0.8 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 3.1 4.0 1.5 3.1 3.3 9.2 2.8 3.2 3.4 2.6 10.4 2.6 3.7 310.9 148.1 1.3 7.0 9.3 227.6 127.4 14.2 0.5 184.7 112.9 2.0 243.1 222.8 448.8 0.0 16.4 2.3 2317.0 76.3 999.6 8.6 434.7 35.3 5.8 498.1 23.1 1.1 402.8 6.5 6.3 150.3 445.3 32.5 11.8 1.4 0.6 2.9 0.0 0.4 1378.2 486.2 0.0 5.2 5.6 20.5 5.6 35.6 0.0 11.5 15.7 0.0 0.5 1.2 617.5 2437.0 18.8 1.8 257.9 2681.1 195.9 219.0 0.7 13.1 0.5 13.7 83.5 130.3 33.3 10.4 6.0 9.4 70.3 1607.7 230.7 EVI2B "CD361, D17S376, EVDB" ENSG00000185862 "Ecotropic viral integration site 2B" P34910 17 31303770-31314105 "CD markers, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 189.0;lymphoid tissue: 169.8" "Cell type enhanced" "Detected in many" "B-cells: 233.2;Kupffer cells: 522.3;Langerhans cells: 169.8;Macrophages: 271.9;monocytes: 426.4;T-cells: 170.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1366.0" "Group enriched" "Detected in all" 5 "granulocytes: 1366.0;monocytes: 381.9" "Cell line enhanced" "Detected in many" "Daudi: 87.9;HL-60: 99.9;HMC-1: 133.3;Karpas-707: 96.4;NB-4: 79.4;RPMI-8226: 147.7;THP-1: 124.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA007346, HPA053383" Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA007346: , HPA053383: " "unprognostic (1.07e-2)" "unprognostic (1.20e-2)" "unprognostic (5.97e-2)" "unprognostic (4.09e-3)" "unprognostic (2.99e-2)" "unprognostic (1.41e-2)" "unprognostic (3.06e-1)" "unprognostic (3.36e-2)" "unprognostic (1.93e-2)" "unprognostic (1.48e-1)" "unprognostic (1.78e-2)" "unprognostic (2.34e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (1.56e-2)" "unprognostic (3.32e-2)" "unprognostic (8.64e-2)" "unprognostic (2.73e-2)" 24.6 11.0 6.4 100.9 7.3 189.0 13.8 7.3 11.6 13.1 8.7 27.9 23.7 7.4 4.3 11.8 7.8 30.5 6.7 6.3 8.4 5.1 24.9 61.1 159.5 13.3 10.3 5.5 3.0 3.8 1.8 15.4 10.8 7.4 30.5 1.2 11.8 6.1 2.0 5.1 39.2 17.0 7.7 158.8 33.7 3.7 8.5 76.4 5.3 12.2 169.8 38.5 4.1 11.1 0.6 0.7 0.0 0.0 6.5 8.3 0.1 0.8 5.8 6.7 12.4 0.0 3.4 87.9 0.1 5.5 26.4 0.6 0.0 1.2 7.5 0.1 0.0 2.1 0.0 0.0 66.0 99.9 133.3 15.3 0.0 3.9 5.3 2.2 6.9 7.3 1.4 96.4 19.8 0.0 29.4 79.4 0.1 0.0 0.0 51.0 0.4 147.7 0.3 0.2 0.0 0.1 0.4 0.2 0.5 0.0 0.0 124.8 7.2 1.9 0.2 0.7 7.0 18.4 0.9 18.9 8.6 34.0 2.2 1005.3 328.9 798.7 79.2 240.1 76.8 183.6 120.8 102.8 149.9 146.2 91.9 87.5 1366.0 44.2 381.9 86.3 173.6 251.4 6.4 7.3 7.3 11.6 6.3 8.4 13.3 10.3 10.8 7.7 8.5 11.1 2.1 0.0 14.8 0.7 233.2 5.4 0.7 0.7 1.8 0.2 1.5 1.7 1.0 2.8 6.7 1.8 0.0 0.6 129.0 1.3 0.0 0.3 8.3 0.1 0.3 5.6 0.0 6.5 2.7 0.0 0.8 4.0 1.5 0.4 82.2 0.0 7.5 2.3 89.1 0.0 3.1 0.1 2.0 522.3 169.8 9.0 0.0 271.9 37.4 11.2 426.4 0.0 117.4 4.0 31.7 1.0 0.0 0.4 110.4 0.4 0.1 1.1 2.4 0.8 19.7 1.2 1.9 0.4 0.4 0.4 3.7 0.3 170.9 0.0 1.3 1.1 EZR VIL2 ENSG00000092820 Ezrin P15311 6 158765741-158819368 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cell shape" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004035, HPA021616, CAB047324, CAB075739" Enhanced Enhanced "Plasma membrane" NA NA 42000000 "Cluster 43: B-cells - Humoral immune response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB004035: AB_2100309, CAB047324: , CAB075739: AB_2665745, HPA021616: AB_1848342" "unprognostic (4.79e-3)" "unprognostic (1.48e-1)" "unprognostic (1.97e-2)" "unprognostic (2.50e-1)" "unprognostic (1.07e-1)" "unprognostic (1.31e-3)" "unprognostic (1.76e-2)" "unprognostic (2.41e-1)" "unprognostic (1.32e-1)" "unprognostic (7.53e-2)" "prognostic unfavorable (1.70e-4)" "unprognostic (5.59e-2)" "prognostic favorable (9.56e-8)" "unprognostic (1.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.34e-2)" "unprognostic (9.00e-2)" 88.2 186.6 100.7 98.4 99.5 135.2 59.8 86.0 96.8 77.1 224.4 133.5 158.8 35.6 78.4 260.3 114.6 116.1 116.3 96.2 95.6 159.1 57.9 173.2 185.6 97.6 105.3 44.7 112.6 447.4 42.8 233.0 91.7 81.4 103.6 10.7 89.9 72.2 46.9 187.8 257.1 36.6 99.3 75.6 273.7 55.9 98.9 108.8 126.1 25.5 216.3 219.0 98.6 91.1 668.3 355.4 86.5 125.0 9.3 10.3 502.7 204.7 67.1 225.7 189.2 420.9 357.7 667.1 197.2 235.2 108.5 497.7 172.2 228.0 259.5 235.3 111.2 14.0 204.9 187.5 223.2 167.7 98.9 16.6 172.9 212.9 205.1 191.4 150.2 90.8 134.9 316.7 132.3 175.9 239.3 199.6 144.5 180.6 117.6 176.9 40.7 152.5 462.1 198.6 156.3 127.2 358.5 507.7 37.9 391.5 124.1 218.5 195.3 72.6 233.4 101.1 319.9 216.5 212.8 566.9 45.4 84.9 88.5 177.2 83.4 103.7 195.9 190.8 233.2 466.5 205.6 245.1 181.9 389.7 108.6 146.3 36.2 133.6 202.9 84.5 385.7 298.2 100.7 99.5 86.0 96.8 96.2 95.6 97.6 105.3 91.7 99.3 98.9 91.1 47.4 951.9 547.8 111.3 799.6 614.7 809.5 202.4 247.0 11.2 240.4 144.4 311.0 154.4 726.2 156.3 0.0 406.1 372.4 806.8 97.8 302.3 10.2 782.9 75.4 71.0 159.9 46.5 0.4 256.1 560.3 213.1 500.5 844.5 119.0 40.8 25.4 37.5 113.3 0.0 0.5 415.3 179.0 79.1 820.5 32.8 135.5 297.5 321.9 12.2 110.5 35.7 62.8 2.0 0.7 618.3 631.2 294.2 564.9 416.7 694.2 238.1 1248.4 5.1 249.8 205.5 136.3 52.5 61.7 430.4 726.5 1243.4 483.8 102.3 312.9 1142.8 F2RL1 "GPR11, PAR2" ENSG00000164251 "F2R like trypsin receptor 1" P55085 5 76818933-76835315 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 59.4;stomach 1: 44.0" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 109.9;Distal enterocytes: 124.7;Gastric mucus-secreting cells: 74.5;Glandular and luminal cells: 74.7;Paneth cells: 86.1;Suprabasal keratinocytes: 168.4;Urothelial cells: 116.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 42.0" "Lineage enriched" "Detected in many" 4 "granulocytes: 42.0" "Cell line enhanced" "Detected in many" "PC-3: 126.0;RPTEC TERT1: 205.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB012989, HPA014091" Approved Approved "Plasma membrane" NA Yes "Cluster 9: Neutrophils - Innate immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB012989: AB_2533199, HPA014091: AB_2668939" "unprognostic (1.29e-2)" "unprognostic (4.05e-2)" "prognostic favorable (3.88e-4)" "unprognostic (1.98e-2)" "unprognostic (8.22e-2)" "prognostic unfavorable (5.88e-4)" "unprognostic (1.36e-1)" "prognostic unfavorable (8.92e-4)" "unprognostic (6.13e-2)" "unprognostic (4.07e-1)" "unprognostic (2.16e-3)" "unprognostic (1.52e-2)" "prognostic favorable (5.86e-7)" "unprognostic (1.11e-1)" "unprognostic (1.74e-1)" "unprognostic (3.76e-2)" "unprognostic (9.73e-2)" 1.0 1.3 0.8 6.2 0.9 1.7 8.0 0.5 0.8 3.6 8.9 59.4 45.8 2.9 4.8 8.2 8.2 29.9 4.6 0.5 0.8 31.8 7.1 4.1 1.4 1.7 2.2 0.5 23.6 5.2 1.5 3.9 1.4 5.0 53.0 2.6 8.9 11.5 0.3 37.5 41.0 2.7 1.0 3.8 44.0 0.6 0.9 1.1 8.3 0.2 1.6 27.5 5.8 0.8 32.7 52.1 4.3 0.2 1.5 4.0 33.1 1.6 17.1 0.9 2.7 45.0 81.8 0.0 69.5 3.7 78.1 54.4 27.1 24.0 1.5 0.1 26.8 0.8 1.0 32.8 10.6 0.0 0.3 5.5 67.3 8.0 49.8 8.0 84.9 7.8 0.4 0.0 0.1 17.6 3.8 0.1 5.7 17.9 126.0 0.1 0.0 0.8 205.9 58.5 2.1 0.4 12.3 12.6 0.3 48.5 5.3 0.3 57.1 0.1 31.8 0.1 0.3 4.8 1.0 0.1 18.7 0.0 1.4 11.9 10.0 1.8 0.4 3.2 2.1 0.5 3.8 1.9 4.7 0.1 3.4 2.1 42.0 0.7 0.5 0.5 1.0 4.0 0.8 0.9 0.5 0.8 0.5 0.8 1.7 2.2 1.4 1.0 0.9 0.8 0.3 9.6 3.7 0.0 0.9 109.9 17.8 4.5 10.8 0.5 10.5 6.3 0.3 32.9 12.7 31.3 0.0 5.4 0.2 124.7 1.9 28.0 0.0 40.9 5.1 1.2 13.1 2.5 0.2 15.0 7.9 2.9 74.5 74.7 2.5 1.0 1.1 9.6 0.9 0.0 1.4 50.8 4.1 1.9 3.8 0.0 0.0 2.1 1.8 1.0 2.6 0.0 0.0 0.0 0.0 44.7 86.1 0.0 0.1 34.1 62.9 19.3 25.0 2.0 0.0 0.4 2.8 0.9 1.3 37.0 168.4 2.1 2.1 0.1 50.7 116.0 F2RL3 PAR4 ENSG00000127533 "F2R like thrombin or trypsin receptor 3" Q96RI0 19 16888999-16892606 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 19.0;lung: 33.4;thyroid gland: 19.2" "Cell type enriched" "Detected in some" 4 "Adipocytes: 110.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 7 "HEL: 30.7;HMC-1: 11.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA031401, HPA042340" Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA031401: , HPA042340: " "unprognostic (6.17e-2)" "unprognostic (1.08e-1)" "unprognostic (2.64e-2)" "unprognostic (3.83e-1)" "unprognostic (3.27e-1)" "unprognostic (8.31e-3)" "unprognostic (2.97e-1)" "unprognostic (3.28e-2)" "unprognostic (6.52e-2)" "unprognostic (2.60e-1)" "unprognostic (6.30e-2)" "unprognostic (3.00e-3)" "prognostic favorable (6.25e-4)" "unprognostic (2.37e-2)" "unprognostic (1.43e-1)" "unprognostic (3.53e-1)" "unprognostic (2.11e-2)" 19.0 2.6 0.7 1.5 0.7 1.3 18.0 1.9 0.7 1.1 1.2 4.3 1.5 1.6 1.6 1.5 1.5 2.8 5.6 0.6 0.7 9.8 0.5 33.4 2.3 0.5 0.6 0.8 9.3 1.1 2.7 1.0 0.5 1.4 1.3 1.2 1.2 0.5 3.2 3.1 4.9 1.0 0.0 1.3 5.0 1.7 1.2 0.4 19.2 0.6 0.9 1.9 1.2 1.3 0.3 0.3 0.8 0.4 0.1 0.2 0.9 0.4 0.1 0.2 0.2 0.5 0.8 0.6 0.6 0.3 0.3 0.6 0.2 0.3 0.3 0.4 0.4 30.7 1.3 0.5 0.2 0.3 11.6 0.0 0.1 0.3 0.2 0.4 0.9 0.6 2.5 1.1 0.2 0.5 0.4 2.9 0.4 0.4 0.3 0.3 0.2 1.0 0.3 0.6 0.5 0.3 0.3 0.2 0.1 0.7 0.6 2.0 1.2 0.6 0.6 0.4 0.3 0.5 0.4 0.6 0.3 0.5 0.4 3.3 0.9 0.7 0.9 0.4 0.8 1.6 1.0 0.8 0.3 1.8 1.4 1.3 2.2 1.8 0.6 1.7 0.8 1.4 0.7 0.7 1.9 0.7 0.6 0.7 0.5 0.6 0.5 0.0 1.2 1.3 110.4 0.0 1.1 0.0 0.3 0.4 0.3 0.3 0.0 0.0 0.3 0.3 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.9 27.5 0.0 0.8 0.0 0.5 0.0 2.7 0.0 0.2 7.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.3 1.0 0.4 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 2.0 0.6 0.0 0.1 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.1 0.4 0.5 0.1 0.3 0.2 0.3 FBLN2 ENSG00000163520 "Fibulin 2" P98095 3 13549125-13638422 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 292.8" "Cell type enhanced" "Detected in many" "Adipocytes: 92.7;Endometrial stromal cells: 84.4;Fibroblasts: 458.4;Leydig cells: 170.9;Peritubular cells: 227.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "myeloid DC: 6.7;naive CD8 T-cell: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 384.0;fHDF/TERT166: 264.3;HMC-1: 311.6;HSkMC: 221.9;U-2197: 139.2" "Group enriched" "Detected in many" 4 "olfactory bulb: 12.4;white matter: 3.1" "Low region specificity" "Detected in all" "HPA001934, CAB018622" Enhanced Supported "Plasma membrane" "Secreted to extracellular matrix" NA NA 35000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB018622: AB_2294196, HPA001934: AB_1078827" "unprognostic (1.19e-1)" "unprognostic (7.76e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (9.48e-4)" "unprognostic (2.82e-2)" "unprognostic (1.05e-1)" "prognostic favorable (3.17e-4)" "unprognostic (8.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.70e-2)" "unprognostic (2.57e-1)" "unprognostic (4.66e-2)" "unprognostic (2.13e-2)" "unprognostic (1.89e-2)" "unprognostic (2.82e-2)" "unprognostic (2.61e-2)" "unprognostic (1.41e-1)" 157.3 7.6 5.9 12.7 7.7 1.0 97.3 5.2 9.0 63.4 6.4 32.7 6.2 31.1 3.2 42.4 26.8 46.2 292.8 7.0 4.9 8.7 3.7 29.2 8.4 5.3 5.3 5.8 8.6 3.0 2.3 80.3 4.8 29.1 11.8 0.6 39.4 8.8 47.7 72.5 19.8 14.7 4.1 6.0 22.3 46.7 6.9 14.2 63.7 48.9 5.6 79.6 56.7 4.4 0.0 1.4 50.9 0.0 384.0 51.7 23.8 124.9 98.2 122.4 80.4 8.1 0.3 0.0 5.9 264.3 0.2 0.2 0.0 0.5 22.9 0.1 0.1 100.7 1.9 0.0 26.0 0.2 311.6 221.9 2.0 19.3 0.0 0.2 0.0 8.6 0.8 0.9 0.6 0.3 5.2 0.6 12.2 0.0 0.7 0.2 0.0 0.5 0.9 0.1 3.0 2.4 0.5 90.3 0.1 13.6 0.2 0.3 0.1 0.1 0.1 139.2 0.1 0.2 0.0 0.0 1.1 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.2 6.7 1.3 0.0 3.7 0.0 0.2 0.0 0.5 0.0 0.9 5.9 7.7 5.2 9.0 7.0 4.9 5.3 5.3 4.8 4.1 6.9 4.4 92.7 0.0 1.5 1.6 3.6 30.8 0.8 10.5 2.2 0.0 1.7 1.9 8.8 0.0 12.3 7.3 2.1 7.8 1.9 0.1 0.0 0.0 3.8 2.9 84.4 43.8 0.0 1.7 0.6 0.2 4.8 458.4 6.1 2.7 23.6 0.6 47.8 0.4 3.6 0.0 0.6 0.0 0.0 1.9 49.8 12.1 170.9 4.5 39.2 26.2 0.3 1.2 0.0 30.7 0.3 0.3 0.0 227.2 1.6 1.2 2.7 0.1 1.4 0.4 13.1 29.7 26.4 3.4 13.5 2.0 28.8 6.2 5.3 0.2 0.0 1.1 FBLN5 "ARMD3, DANCE, EVEC, UP50" ENSG00000140092 "Fibulin 5" Q9UBX5 14 91869411-91947987 "Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion" "Age-related macular degeneration, Charcot-Marie-Tooth disease, Disease variant, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 6 "Fibroblasts: 209.4;Leydig cells: 626.6;Peritubular cells: 794.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 6.6" "Group enriched" "Detected in many" 19 "granulocytes: 6.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "ASC diff: 457.1;ASC TERT1: 234.6;BJ: 202.0;BJ hTERT+: 202.5;fHDF/TERT166: 394.6;HSkMC: 216.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000848, HPA000868, CAB025843" Supported Uncertain "Plasma membrane" "Secreted to extracellular matrix" NA NA 12000000 "Cluster 46: Basophils - DNA binding" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025843: , HPA000848: AB_1078620, HPA000868: AB_1078619" "unprognostic (5.53e-3)" "unprognostic (1.14e-1)" "unprognostic (7.78e-2)" "unprognostic (9.29e-2)" "unprognostic (5.55e-3)" "unprognostic (4.73e-2)" "prognostic favorable (6.75e-4)" "unprognostic (5.21e-3)" "unprognostic (4.76e-2)" "unprognostic (1.25e-2)" "unprognostic (3.74e-2)" "unprognostic (1.90e-1)" "unprognostic (7.26e-2)" "unprognostic (1.56e-3)" "unprognostic (1.73e-1)" "unprognostic (5.18e-2)" "unprognostic (3.17e-3)" 182.2 73.4 10.7 17.7 12.8 7.5 110.4 7.4 12.5 124.9 15.7 80.3 19.1 178.4 40.0 26.8 143.0 130.2 211.1 9.4 8.6 108.4 29.3 164.8 25.5 15.5 10.9 107.3 46.4 16.8 14.5 67.0 14.2 49.0 20.6 0.6 55.8 70.9 30.4 66.9 52.7 88.7 13.1 130.9 68.9 35.6 12.7 21.8 79.5 36.0 15.7 117.5 93.3 7.5 0.0 1.6 0.2 0.0 457.1 234.6 22.5 202.0 202.5 5.8 4.5 4.7 0.0 0.0 4.2 394.6 0.6 0.1 9.8 1.0 1.0 0.0 2.3 0.4 4.7 0.0 74.2 0.0 0.1 216.6 0.4 3.9 14.1 2.8 10.4 0.1 0.0 0.1 25.3 0.4 0.5 0.5 0.5 0.0 0.5 0.4 30.2 0.2 1.2 0.1 0.2 0.1 12.3 0.7 2.6 7.0 2.9 0.3 1.9 3.2 6.6 3.8 0.1 0.1 0.0 0.2 0.4 0.0 0.0 6.6 0.1 2.2 0.8 0.2 0.5 0.0 0.3 0.1 0.0 0.1 1.1 1.8 2.5 0.0 0.2 0.0 0.1 0.4 10.7 12.8 7.4 12.5 9.4 8.6 15.5 10.9 14.2 13.1 12.7 7.5 31.4 83.3 13.1 0.0 2.1 9.2 2.4 7.1 1.8 0.0 11.2 9.3 5.2 0.0 11.5 5.5 0.0 2.5 2.5 0.1 5.9 4.7 5.9 13.3 67.4 15.2 0.0 0.4 2.6 4.7 2.5 209.4 2.0 12.0 2.5 1.8 34.2 0.4 7.8 0.0 3.6 0.1 18.3 2.5 18.4 27.5 626.6 5.8 21.4 15.9 1.6 0.0 8.2 5.0 2.3 2.2 0.0 794.8 0.7 1.3 0.0 32.5 21.4 0.0 6.6 28.0 14.5 3.0 2.8 1.3 8.7 3.7 15.5 3.5 0.4 1.2 FCAR CD89 ENSG00000186431 "Fc fragment of IgA receptor" P24071 19 54874235-54891420 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "IgA-binding protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 26.1;lung: 10.5;lymphoid tissue: 13.5" "Group enriched" "Detected in some" 6 "Kupffer cells: 12.8;Macrophages: 18.0" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "classical monocyte: 1.2;neutrophil: 4.0" "Group enriched" "Detected in many" 27 "granulocytes: 4.0;monocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA014050 Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014050: AB_1846338" "unprognostic (1.46e-1)" "unprognostic (5.74e-2)" "unprognostic (1.30e-1)" "unprognostic (4.71e-3)" "unprognostic (3.46e-1)" "unprognostic (2.02e-1)" "unprognostic (7.99e-2)" "unprognostic (1.54e-2)" "unprognostic (1.59e-2)" "unprognostic (4.70e-2)" "unprognostic (1.41e-2)" "unprognostic (7.05e-2)" "unprognostic (4.19e-6)" "unprognostic (9.23e-2)" "unprognostic (8.10e-3)" "unprognostic (8.04e-3)" "unprognostic (9.81e-2)" 4.5 0.3 0.0 1.0 0.0 26.1 0.7 0.0 0.3 0.2 0.0 0.6 0.0 0.2 0.0 0.3 3.4 0.0 1.5 0.0 0.0 0.5 1.7 10.5 0.0 0.1 0.0 0.3 0.2 0.0 0.3 0.0 0.1 0.3 0.0 0.0 0.4 0.0 0.4 0.1 0.4 0.1 0.0 13.5 0.8 0.1 0.0 0.0 0.5 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.3 0.1 0.3 0.0 0.0 0.2 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 12.8 0.3 0.0 0.0 18.0 0.0 1.0 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.7 0.5 0.0 0.3 0.3 0.1 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.1 FFAR1 "FFA1R, GPR40" ENSG00000126266 "Free fatty acid receptor 1" O14842 19 35351552-35353862 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 2.8;brain: 4.8;ovary: 2.5;pancreas: 4.4" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 1.8;granulocytes: 1.3;Granulosa cells: 1.4" "Cancer enriched" "Detected in single" 13 "pancreatic cancer: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-698: 1.6" "Not detected" "Not detected" HPA048933 Supported "Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA048933: " "unprognostic (9.49e-2)" "unprognostic (2.08e-1)" "unprognostic (1.59e-1)" "unprognostic (1.50e-1)" "unprognostic (1.03e-1)" "unprognostic (4.51e-2)" "unprognostic (1.03e-2)" "unprognostic (4.46e-2)" "unprognostic (6.19e-2)" "unprognostic (9.56e-3)" 0.0 0.0 1.5 0.1 2.1 2.8 0.0 1.4 1.9 0.0 0.8 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 1.3 1.5 0.0 0.0 0.1 0.4 2.1 1.6 2.5 4.4 0.0 0.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.3 0.3 0.6 0.2 1.9 0.0 0.0 0.0 0.1 0.0 0.0 4.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.5 2.1 1.4 1.9 1.3 1.5 2.1 1.6 2.1 1.3 1.9 4.8 0.1 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.4 0.0 0.0 1.3 1.4 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 FFAR4 "GPR120, GPR129, O3FAR1, PGR4" ENSG00000186188 "Free fatty acid receptor 4" Q5NUL3 10 93566665-93604480 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins, Transporters" "Differentiation, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 11.4;pituitary gland: 11.0" "Cell type enriched" "Detected in some" 4 "Intestinal goblet cells: 125.7" "Cancer enhanced" "Detected in some" "colorectal cancer: 4.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "OE19: 12.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042563 Uncertain "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "HPA042563: AB_10794762" "unprognostic (1.96e-1)" "unprognostic (1.06e-2)" "unprognostic (1.14e-2)" "unprognostic (4.21e-2)" "unprognostic (2.12e-1)" "unprognostic (4.98e-4)" "unprognostic (1.41e-3)" "unprognostic (1.20e-2)" "unprognostic (2.34e-2)" "unprognostic (7.87e-2)" "unprognostic (9.51e-2)" "unprognostic (1.49e-1)" "unprognostic (3.85e-2)" "unprognostic (5.32e-2)" "unprognostic (2.71e-1)" "unprognostic (1.02e-1)" "unprognostic (1.49e-1)" 4.1 0.4 1.2 0.7 1.3 0.1 1.3 0.6 1.2 0.1 0.3 8.3 0.5 0.0 0.0 0.2 1.0 0.5 0.3 1.0 1.8 0.1 0.4 3.6 0.2 0.6 0.8 0.0 0.6 0.1 11.0 0.1 0.5 0.1 11.4 0.2 0.1 0.0 0.3 0.9 0.6 0.2 0.3 0.1 0.5 1.5 2.6 0.3 0.1 0.1 0.1 0.1 0.0 0.7 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.3 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.1 12.9 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.9 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.2 1.2 1.3 0.6 1.2 1.0 1.8 0.6 0.8 0.5 0.3 2.6 0.7 0.2 0.0 0.5 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.2 0.8 0.4 7.2 0.6 0.0 0.0 0.2 0.0 28.1 0.0 0.8 27.8 0.1 0.0 0.3 20.9 0.0 3.2 0.0 0.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 7.4 0.0 2.0 125.7 0.0 7.2 4.4 16.7 0.6 7.6 1.8 3.7 0.5 0.0 0.0 0.0 0.3 0.9 23.0 0.0 0.0 0.3 0.3 0.0 0.0 0.2 0.0 0.5 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 5.9 0.3 FGD5 "FLJ00274, FLJ39957, ZFYVE23" ENSG00000154783 "FYVE, RhoGEF and PH domain containing 5" Q6ZNL6 3 14810853-14934571 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 51.3;Endothelial cells: 44.7;Hepatic stellate cells: 55.6;Microglial cells: 25.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 94.9;TIME: 81.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014436, HPA014536, HPA019191" Uncertain Supported "Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA014436: , HPA014536: AB_1848518, HPA019191: AB_1848519" "unprognostic (2.57e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (3.28e-2)" "unprognostic (2.02e-2)" "unprognostic (1.03e-3)" "unprognostic (1.08e-1)" "unprognostic (4.10e-2)" "unprognostic (6.34e-2)" "unprognostic (5.53e-2)" "unprognostic (1.46e-1)" "unprognostic (9.39e-2)" "unprognostic (6.84e-3)" "unprognostic (1.71e-2)" "unprognostic (3.46e-1)" "unprognostic (1.32e-2)" "prognostic favorable (7.50e-4)" 19.8 4.4 4.8 5.6 4.3 0.3 15.0 4.1 4.9 10.4 3.4 5.3 9.2 11.3 2.3 5.7 8.5 11.9 11.5 3.0 2.9 10.1 3.1 20.6 4.2 4.5 11.5 5.3 2.2 3.5 3.2 17.7 4.8 5.3 4.6 0.2 3.7 4.4 6.8 5.4 7.0 11.4 3.2 25.0 4.6 4.3 6.7 2.0 7.5 13.4 3.6 7.7 5.6 3.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 94.9 0.1 0.0 0.0 0.0 0.0 0.4 0.2 5.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.6 0.4 0.0 81.1 0.0 6.6 21.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 4.3 4.1 4.9 3.0 2.9 4.5 11.5 4.8 3.2 6.7 3.0 51.3 0.0 4.6 0.0 0.9 3.1 0.2 0.0 1.2 0.1 1.3 1.9 4.4 1.5 0.6 0.0 0.0 0.3 0.4 0.1 1.9 0.2 7.3 0.4 5.3 44.7 0.0 5.3 3.4 0.2 0.1 11.3 1.1 0.3 0.0 0.0 55.6 1.3 10.5 0.0 8.6 0.2 0.0 2.2 5.9 9.9 11.5 3.3 1.8 25.3 0.0 0.0 1.0 0.5 0.3 4.8 2.5 4.5 0.0 0.3 1.0 7.0 0.0 0.2 0.0 4.9 2.4 0.2 3.6 0.1 1.8 0.5 0.7 2.3 0.5 0.2 FILIP1L "DOC-1, GIP130" ENSG00000168386 "Filamin A interacting protein 1 like" Q4L180 3 99830141-100114513 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 210.1;Early spermatids: 376.7;Sertoli cells: 256.4;Skeletal myocytes: 184.2;Smooth muscle cells: 351.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.9" "Group enriched" "Detected in many" 4 "dendritic cells: 2.1;monocytes: 2.9" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 84.2;HDLM-2: 79.9;TIME: 145.8" "Region enriched" "Detected in many" 7 "olfactory bulb: 18.0" "Low region specificity" "Detected in all" HPA043133 Approved Approved "Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA043133: AB_10793991" "unprognostic (9.14e-2)" "unprognostic (2.16e-1)" "unprognostic (7.73e-2)" "unprognostic (5.25e-2)" "unprognostic (6.68e-2)" "unprognostic (1.06e-2)" "unprognostic (4.40e-2)" "unprognostic (1.29e-1)" "unprognostic (2.08e-2)" "unprognostic (2.18e-1)" "unprognostic (1.02e-1)" "unprognostic (3.32e-1)" "prognostic unfavorable (9.40e-4)" "unprognostic (2.46e-2)" "unprognostic (9.44e-2)" "unprognostic (5.30e-2)" "unprognostic (1.82e-3)" 77.1 21.7 4.9 52.4 6.3 0.8 32.6 4.8 6.6 63.8 4.0 57.7 28.4 117.6 23.8 56.0 31.2 90.9 54.8 6.2 4.4 24.0 28.1 30.7 30.1 9.6 4.2 76.4 35.5 17.5 3.9 43.9 9.7 67.9 29.8 4.7 9.3 54.3 140.4 16.8 41.2 151.7 3.7 42.9 46.7 22.0 3.6 11.9 20.1 161.5 22.3 101.5 21.9 4.0 59.0 0.0 22.3 0.1 35.8 30.2 2.0 29.4 58.8 50.2 56.5 17.8 0.2 0.2 5.0 84.2 13.2 7.1 0.0 14.4 59.0 79.9 0.6 4.8 0.2 23.3 17.8 1.4 0.0 24.2 5.1 5.6 0.0 32.0 22.8 0.0 3.8 0.5 7.7 0.1 5.2 1.2 1.3 3.1 0.0 0.1 26.1 0.7 33.5 1.0 2.0 3.7 0.4 0.4 0.1 11.7 0.0 10.5 145.8 8.8 0.2 1.9 15.5 4.2 0.2 0.3 6.5 0.4 0.0 0.2 0.4 0.0 0.1 1.0 0.0 0.6 0.1 0.1 2.1 0.6 0.0 0.1 0.2 0.4 2.9 0.4 0.1 0.3 4.9 6.3 4.8 6.6 6.2 4.4 9.6 4.2 9.7 3.7 3.6 4.0 92.9 16.0 23.1 9.4 4.1 27.8 56.7 7.9 2.2 11.8 12.3 6.5 145.7 35.8 2.3 5.5 8.4 1.1 1.8 2.1 1.9 210.1 376.7 2.3 60.5 77.2 3.0 0.0 42.0 109.3 0.7 145.2 21.9 2.4 34.8 16.3 41.0 0.7 3.2 106.0 25.8 5.7 6.1 36.3 98.9 180.2 83.0 86.1 17.8 25.3 17.7 0.9 0.0 22.1 21.6 43.7 0.2 104.2 3.0 5.1 5.4 2.6 1.9 6.0 256.4 184.2 351.9 40.1 2.5 1.5 22.7 3.1 8.8 41.8 3.2 3.5 FKBP2 "FKBP-13, FKBP13, PPIase" ENSG00000173486 "FKBP prolyl isomerase 2" P26885 11 64241003-64244132 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Isomerase, Rotamase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 929.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025561, HPA049405" Enhanced Approved "Plasma membrane" "Intracellular and membrane" No No 510000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 68: Epididymis - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "CAB025561: , HPA049405: AB_2680749" "unprognostic (4.94e-2)" "unprognostic (1.12e-1)" "unprognostic (5.77e-2)" "unprognostic (2.66e-3)" "unprognostic (7.40e-2)" "unprognostic (1.92e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-1)" "unprognostic (3.23e-1)" "unprognostic (5.91e-3)" "unprognostic (5.86e-2)" "unprognostic (7.18e-2)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (5.23e-1)" "unprognostic (2.30e-1)" "unprognostic (3.57e-2)" 64.7 127.6 185.1 77.5 187.6 50.1 58.3 192.7 234.7 113.1 210.8 105.7 136.3 81.1 397.7 68.4 94.4 77.2 117.4 185.0 196.9 122.7 197.3 62.7 70.7 199.9 199.6 75.3 280.1 160.4 200.9 73.1 197.7 92.5 84.2 37.1 208.9 146.7 33.3 60.9 107.3 72.6 183.4 67.5 113.4 74.7 194.3 59.0 187.6 48.4 70.4 85.7 61.6 196.0 101.2 144.8 82.8 165.9 178.5 98.2 94.6 132.9 146.4 108.8 101.4 148.1 257.0 80.8 195.4 186.5 148.2 134.7 70.5 121.0 51.3 101.4 54.5 90.0 196.5 158.3 231.6 74.5 125.5 116.0 169.3 145.4 163.5 156.9 86.9 76.6 61.0 253.6 138.1 186.7 85.1 112.6 92.6 211.1 130.0 70.8 70.9 299.2 198.9 120.7 110.0 91.3 85.4 263.2 147.9 59.5 98.1 69.5 68.9 123.8 100.9 182.8 72.6 128.5 48.6 69.0 156.7 80.6 142.8 276.8 173.1 25.9 178.9 191.2 230.8 170.1 139.2 176.4 172.2 165.0 90.4 131.5 68.6 162.9 162.7 929.1 55.9 126.7 185.1 187.6 192.7 234.7 185.0 196.9 199.9 199.6 197.7 183.4 194.3 196.0 129.5 147.4 168.0 20.9 179.7 164.4 251.0 447.2 125.2 86.4 205.0 185.4 134.7 275.9 270.6 389.9 22.9 279.8 174.4 534.1 412.8 270.8 126.4 212.5 206.3 138.6 342.6 41.4 11.3 254.2 386.9 167.0 179.4 258.5 144.0 146.5 148.5 754.4 228.4 32.0 14.8 508.2 305.2 100.1 201.7 99.0 230.2 140.7 300.6 16.9 151.7 181.7 111.2 11.1 20.6 292.2 424.7 255.1 765.2 315.5 594.7 792.2 241.9 83.3 184.1 138.4 221.3 327.1 282.1 136.6 168.1 620.5 123.6 138.8 339.4 312.0 FZD1 DKFZp564G072 ENSG00000157240 "Frizzled class receptor 1" Q9UP38 7 91264433-91271326 "Cancer-related genes, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 44.9;Cholangiocytes: 45.8;Horizontal cells: 141.3;Peritubular cells: 45.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 2.0;non-classical monocyte: 2.8" "Lineage enriched" "Detected in single" 5 "monocytes: 2.8" "Cell line enhanced" "Detected in many" "AF22: 24.8;HSkMC: 32.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB013008 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB013008: " "unprognostic (1.46e-1)" "unprognostic (1.70e-1)" "unprognostic (1.15e-1)" "unprognostic (3.16e-2)" "unprognostic (4.51e-3)" "unprognostic (2.09e-1)" "unprognostic (5.29e-3)" "unprognostic (3.70e-2)" "unprognostic (2.36e-2)" "unprognostic (5.48e-3)" "unprognostic (2.14e-1)" "unprognostic (7.39e-3)" "prognostic favorable (8.87e-7)" "unprognostic (1.05e-2)" "unprognostic (4.16e-2)" "unprognostic (5.53e-2)" "unprognostic (4.13e-2)" 5.4 4.4 2.4 2.7 2.5 1.1 10.7 5.8 2.4 9.9 11.1 5.9 5.1 8.6 4.3 5.2 5.5 5.7 12.7 4.7 2.9 9.6 2.5 10.7 1.3 2.5 6.2 10.1 4.7 2.4 3.9 10.0 2.3 10.3 3.7 2.0 9.0 16.4 1.9 10.4 5.1 5.3 2.3 3.2 4.6 1.6 3.4 1.8 20.5 2.4 1.3 6.4 11.2 2.0 0.8 2.5 24.8 2.6 19.8 17.0 4.5 9.2 5.8 3.3 2.3 1.1 4.3 0.0 2.2 5.9 4.2 4.7 3.9 2.0 2.2 0.0 4.9 0.2 4.6 1.3 1.4 4.2 1.0 32.3 3.6 7.6 2.4 12.6 0.7 2.8 1.5 3.6 9.7 6.2 0.8 1.1 6.4 1.3 4.2 5.1 15.3 0.4 5.3 11.8 3.4 6.5 7.0 5.6 1.6 5.7 3.0 3.8 3.8 13.9 10.4 15.0 3.8 3.3 2.5 0.4 15.0 3.5 16.5 0.0 0.6 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 2.8 0.0 0.0 0.2 2.4 2.5 5.8 2.4 4.7 2.9 2.5 6.2 2.3 2.3 3.4 2.0 5.7 3.2 1.5 4.6 1.1 4.2 44.9 7.0 10.8 1.6 27.7 29.5 18.5 45.8 4.6 12.9 2.1 3.4 0.6 7.4 0.0 4.3 0.3 12.0 13.1 4.5 3.5 0.8 0.6 2.0 2.2 18.5 2.0 15.7 12.7 1.8 15.4 0.9 3.5 141.3 1.0 3.0 4.1 17.4 16.2 1.1 33.2 14.3 17.8 1.9 4.6 3.0 1.0 1.0 0.2 1.9 4.8 45.1 0.4 11.7 6.0 11.6 2.4 2.9 0.0 6.2 10.3 0.5 3.7 9.1 5.1 2.1 0.6 2.6 4.6 7.3 FZD6 Hfz6 ENSG00000164930 "Frizzled class receptor 6" O60353 8 103298433-103332866 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 73.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "NK-cell: 4.0" "Lineage enriched" "Detected in single" 4 "NK-cells: 4.0" "Cell line enhanced" "Detected in many" "hTCEpi: 127.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017991 Approved Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA017991: AB_1849138" "unprognostic (8.22e-3)" "unprognostic (2.64e-1)" "unprognostic (4.75e-2)" "unprognostic (2.57e-1)" "unprognostic (1.22e-2)" "unprognostic (6.99e-2)" "unprognostic (4.01e-2)" "unprognostic (2.74e-1)" "unprognostic (2.43e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (1.20e-6)" "unprognostic (3.62e-2)" "unprognostic (1.83e-1)" "unprognostic (2.86e-1)" "unprognostic (1.32e-1)" "unprognostic (4.92e-2)" "unprognostic (7.54e-2)" 11.7 10.6 3.0 4.2 2.8 1.0 15.1 3.1 4.3 14.2 5.7 7.0 5.7 13.0 9.5 18.7 23.5 10.6 9.1 2.9 3.0 14.5 4.0 18.6 5.1 3.8 3.1 5.4 11.2 25.3 9.8 15.1 3.8 12.6 7.0 4.6 11.7 10.3 2.0 24.0 4.6 9.3 3.0 4.0 7.4 3.6 3.3 10.0 22.3 5.6 9.9 21.6 10.2 3.2 59.8 11.0 29.6 0.0 7.9 20.6 17.1 31.0 34.1 27.2 17.6 6.2 47.8 0.0 51.4 29.7 9.1 90.3 16.8 65.7 51.0 13.5 18.0 31.4 12.2 8.5 93.4 0.0 0.0 23.0 127.6 29.4 91.5 67.1 58.2 7.0 3.2 27.0 31.5 25.5 29.8 2.7 6.7 4.7 20.6 2.3 12.3 0.0 59.1 39.5 10.0 7.9 44.8 22.8 59.9 15.8 0.0 11.6 4.1 6.1 32.0 24.9 32.7 6.4 3.7 13.3 18.0 0.0 40.4 0.0 0.0 0.1 0.2 0.0 0.0 0.5 0.8 0.4 0.3 0.5 0.9 0.4 0.0 4.0 0.0 0.1 0.4 0.2 3.0 2.8 3.1 4.3 2.9 3.0 3.8 3.1 3.8 3.0 3.3 3.2 38.3 25.6 22.5 10.1 2.8 46.9 15.9 51.1 42.7 4.1 16.1 12.7 4.8 8.6 35.4 12.9 2.1 22.7 2.1 4.9 0.0 11.7 9.6 51.0 5.8 42.0 5.3 6.7 19.9 8.2 7.1 7.0 14.8 73.6 0.0 11.2 13.9 3.7 2.4 6.7 7.3 7.4 26.4 1.0 5.1 2.9 1.2 1.3 14.2 16.9 0.7 11.8 1.0 8.5 3.6 9.5 3.2 1.5 8.6 13.4 2.8 7.1 53.8 4.8 0.0 1.6 7.7 7.0 0.8 41.9 44.6 14.6 3.0 1.7 5.6 23.2 GAB2 KIAA0571 ENSG00000033327 "GRB2 associated binding protein 2" Q9UQC2 11 78215293-78418348 "Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 97.9" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 147.9;Microglial cells: 204.2;Oligodendrocyte precursor cells: 142.7;Oligodendrocytes: 480.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 13.0;neutrophil: 20.1" "Lineage enriched" "Detected in many" 4 "granulocytes: 20.1" "Cell line enhanced" "Detected in many" "SH-SY5Y: 62.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000271, HPA001368, CAB022159" Enhanced Supported "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB022159: , HPA000271: AB_1078925, HPA001368: AB_2666287" "unprognostic (2.51e-2)" "unprognostic (1.90e-1)" "unprognostic (3.56e-3)" "unprognostic (1.99e-3)" "unprognostic (1.04e-2)" "unprognostic (4.69e-2)" "unprognostic (4.47e-2)" "unprognostic (1.08e-1)" "unprognostic (6.54e-2)" "unprognostic (1.37e-1)" "unprognostic (2.25e-1)" "unprognostic (1.74e-1)" "prognostic favorable (9.32e-5)" "unprognostic (6.95e-2)" "unprognostic (4.35e-1)" "unprognostic (3.99e-2)" "unprognostic (1.67e-2)" 18.5 8.2 69.5 12.9 80.7 39.9 11.6 56.2 65.3 14.8 31.2 9.4 14.4 19.8 3.1 8.9 13.6 9.3 14.5 54.5 68.4 6.7 4.4 20.0 7.0 79.4 70.9 20.0 6.8 6.8 8.8 15.5 74.0 7.0 11.0 3.5 7.1 7.1 6.4 13.3 10.7 17.3 68.0 13.1 8.2 5.7 72.0 21.3 6.6 6.8 5.8 10.6 10.9 97.9 3.7 3.1 8.8 1.0 12.7 5.4 39.1 5.7 6.8 4.0 3.3 23.8 1.9 1.1 24.8 7.9 1.0 5.9 21.2 0.5 5.2 36.3 2.2 14.6 5.9 4.2 6.3 5.6 2.8 6.1 1.9 15.6 2.4 11.8 23.4 4.2 38.8 1.2 6.7 1.5 2.8 13.8 2.8 8.4 4.4 27.4 8.5 0.5 7.3 13.4 7.6 62.1 1.4 2.9 14.4 12.7 13.2 15.5 19.4 1.8 4.5 15.2 1.4 9.8 1.5 0.6 1.5 8.6 16.8 13.0 3.1 0.9 0.0 1.7 0.0 0.7 0.0 0.0 1.0 0.4 0.0 0.0 20.1 0.0 4.9 2.2 0.2 1.0 69.5 80.7 56.2 65.3 54.5 68.4 79.4 70.9 74.0 68.0 72.0 97.9 6.6 3.2 20.7 57.5 8.7 2.0 0.7 0.5 0.6 4.3 3.6 2.7 10.9 1.5 1.1 0.0 0.0 5.0 4.0 9.2 0.0 2.5 7.0 5.5 9.1 7.6 10.7 4.2 80.7 6.4 16.6 6.9 6.6 10.6 5.7 50.4 5.3 0.8 12.1 16.8 147.9 4.0 4.1 29.5 17.5 5.1 8.1 22.8 7.2 204.2 17.5 0.5 1.0 142.7 480.3 8.2 3.3 10.9 4.2 4.3 10.5 0.8 2.6 2.1 13.1 8.3 5.4 3.7 1.7 1.8 2.8 22.2 3.5 3.5 8.9 2.2 GABRG1 ENSG00000163285 "Gamma-aminobutyric acid type A receptor subunit gamma1" Q8N1C3 4 46035769-46124054 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 44.7" "Cell type enriched" "Detected in some" 8 "Astrocytes: 135.5" "Cancer enriched" "Detected in single" 8 "glioma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-266/70: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035622, HPA058102" Approved Supported "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA035622: AB_10603669, HPA058102: " "unprognostic (2.50e-1)" "unprognostic (2.20e-1)" "unprognostic (6.06e-2)" "unprognostic (1.46e-2)" "unprognostic (7.39e-4)" "unprognostic (1.23e-1)" "unprognostic (1.28e-1)" "unprognostic (1.99e-1)" 0.1 0.1 21.6 0.0 20.6 0.0 0.0 19.0 27.3 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 19.4 31.7 0.0 0.0 0.0 0.0 24.8 38.0 1.2 0.0 0.0 0.6 0.0 23.9 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 21.1 0.1 0.0 0.2 44.7 0.0 0.1 0.0 0.0 0.0 0.0 23.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.6 20.6 19.0 27.3 19.4 31.7 24.8 38.0 23.9 21.1 44.7 23.1 0.3 0.0 0.0 135.5 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 12.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 11.2 0.0 15.4 0.0 2.5 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 6.6 0.0 1.8 0.1 0.9 0.0 0.0 0.0 0.0 0.1 0.0 0.0 GALR1 "GALNR, GALNR1" ENSG00000166573 "Galanin receptor 1" P47211 18 77249848-77277900 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 1.4;brain: 1.9;pituitary gland: 1.4" "Cell type enhanced" "Detected in some" "Early spermatids: 68.1;Enteroendocrine cells: 17.6;Oligodendrocyte precursor cells: 42.7;Respiratory ciliated cells: 11.7" "Cancer enriched" "Detected in single" 6 "glioma: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Region enhanced" "Detected in some" "hypothalamus: 5.2" "Low region specificity" "Detected in many" HPA074584 Supported "Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA074584: " "unprognostic (1.65e-1)" "unprognostic (1.56e-2)" "unprognostic (2.85e-1)" "unprognostic (3.00e-1)" "unprognostic (2.11e-1)" "unprognostic (2.77e-3)" "unprognostic (1.31e-2)" "unprognostic (5.34e-3)" "unprognostic (7.33e-3)" "unprognostic (9.49e-2)" "unprognostic (2.18e-1)" 0.1 1.4 0.8 0.1 0.5 0.2 0.1 0.1 0.8 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.7 1.5 0.0 0.2 0.0 0.0 1.1 1.6 0.0 0.0 0.2 1.4 0.0 0.8 0.2 0.1 0.5 0.0 0.2 0.0 0.1 0.2 0.0 1.3 0.0 0.1 0.1 1.9 0.0 0.1 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.5 0.1 0.8 0.7 1.5 1.1 1.6 0.8 1.3 1.9 0.8 4.2 0.0 3.6 0.0 0.0 0.0 1.1 0.0 0.0 4.2 0.0 0.0 0.6 0.0 0.6 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.1 0.3 0.1 0.3 17.6 0.0 1.4 0.0 0.0 1.0 0.0 0.3 1.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 8.0 0.0 0.3 0.0 0.0 0.1 0.2 1.0 42.7 0.3 0.0 1.1 0.0 0.0 0.8 0.0 0.1 11.7 0.4 0.0 3.1 0.2 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 1.2 GAP43 "B-50, GAP-43, PP46" ENSG00000172020 "Growth associated protein 43" P17677 3 115623510-115721490 "Plasma proteins, Predicted intracellular proteins, Transporters" "Differentiation, Growth regulation, Neurogenesis" "Calmodulin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 26 "brain: 277.0" "Cell type enriched" "Detected in some" 4 "Excitatory neurons: 270.2" "Cancer enriched" "Detected in many" 43 "glioma: 245.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 37.9;NTERA-2: 81.1;SCLC-21H: 52.2;SH-SY5Y: 39.6;U-87 MG: 18.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004417, HPA013392, HPA015600, CAB078783" Enhanced Supported Enhanced "Plasma membrane" NA NA 35000 "Cluster 32: T-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004417: AB_627660, CAB078783: AB_2620096, HPA013392: AB_1849468, HPA015600: AB_1849466" "unprognostic (1.24e-1)" "unprognostic (1.31e-1)" "unprognostic (1.15e-2)" "unprognostic (5.72e-5)" "unprognostic (7.44e-3)" "unprognostic (2.19e-2)" "unprognostic (3.97e-3)" "unprognostic (3.15e-3)" "unprognostic (6.08e-4)" "unprognostic (3.33e-1)" "unprognostic (2.17e-2)" "unprognostic (1.62e-1)" "unprognostic (5.35e-8)" "unprognostic (1.15e-1)" "unprognostic (1.09e-1)" "unprognostic (2.78e-2)" "unprognostic (1.29e-3)" 0.6 6.3 131.6 7.5 149.2 0.0 0.9 36.3 277.0 0.6 0.0 10.5 2.5 0.2 0.1 1.1 0.2 4.7 4.3 149.9 187.2 0.2 0.2 0.3 0.2 55.6 156.5 0.2 0.8 0.0 10.0 1.7 113.3 0.9 4.8 8.0 2.1 0.3 0.3 0.5 5.5 4.3 28.5 0.0 2.9 0.4 150.7 0.1 0.2 0.6 0.4 1.3 1.9 121.0 0.0 0.0 37.9 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.2 0.0 0.1 0.0 0.0 0.4 0.2 0.1 0.4 0.0 0.0 0.1 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.6 0.0 0.5 0.0 0.0 0.0 9.1 0.2 0.0 0.0 0.0 81.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.2 39.6 0.0 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.5 0.1 0.1 0.1 0.0 0.0 18.9 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 131.6 149.2 36.3 277.0 149.9 187.2 55.6 156.5 113.3 28.5 150.7 121.0 0.1 0.0 0.0 20.9 0.0 0.3 0.0 0.0 0.0 3.7 0.0 0.0 0.5 0.0 0.0 0.0 2.1 0.1 0.4 0.0 0.0 0.0 1.0 0.0 0.8 5.1 0.0 0.0 270.2 0.0 0.1 4.5 0.0 0.0 0.0 1.5 0.0 0.0 0.8 0.0 62.5 0.0 0.0 0.0 1.2 1.8 0.0 0.0 1.8 29.0 0.0 1.4 0.0 40.2 20.2 0.8 0.0 0.0 0.4 0.0 0.0 0.2 0.0 3.5 0.0 2.0 1.1 0.9 1.7 0.0 0.1 0.0 0.1 0.3 0.0 0.0 GLP2R ENSG00000065325 "Glucagon like peptide 2 receptor" O95838 17 9822206-9892099 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 12.2;intestine: 13.5;urinary bladder: 11.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 4.2;Excitatory neurons: 6.4;Leydig cells: 3.1;Rod photoreceptor cells: 23.3" "Cancer enhanced" "Detected in single" "pancreatic cancer: 1.1" "Group enriched" "Detected in many" 6 "basal ganglia: 3.0;cerebral cortex: 3.6;hippocampal formation: 3.2;white matter: 1.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HeLa: 78.1" "Group enriched" "Detected in some" 5 "cerebral cortex: 2.1;hippocampal formation: 2.4" "Low region specificity" "Detected in all" "CAB022690, HPA049244" Supported Supported "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "CAB022690: , HPA049244: AB_2680690" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (2.66e-3)" "unprognostic (2.21e-2)" "unprognostic (3.81e-3)" "unprognostic (2.09e-1)" "unprognostic (1.39e-2)" "unprognostic (5.15e-2)" "unprognostic (7.63e-2)" "unprognostic (7.14e-2)" "unprognostic (2.19e-1)" "unprognostic (6.16e-3)" "unprognostic (3.40e-8)" "unprognostic (9.53e-5)" "unprognostic (5.51e-2)" "unprognostic (3.92e-1)" "unprognostic (6.48e-3)" 8.1 0.3 0.4 0.7 3.0 0.0 0.8 0.0 3.6 6.0 0.0 13.5 9.9 1.2 0.0 0.7 1.6 12.2 0.6 3.2 0.0 0.3 2.7 1.0 0.6 0.0 0.2 0.4 1.6 0.0 0.0 1.1 0.0 0.1 6.0 3.4 0.0 0.1 0.1 0.1 8.2 1.9 0.0 0.1 3.7 0.4 0.0 0.1 0.2 0.2 0.2 11.8 1.5 1.7 0.0 16.6 0.0 0.0 0.8 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.5 0.0 0.0 0.0 2.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 78.1 0.6 1.0 0.1 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 3.0 0.0 3.6 3.2 0.0 0.0 0.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.0 6.4 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.4 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.5 0.0 1.5 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 23.3 0.0 1.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GNB2 ENSG00000172354 "G protein subunit beta 2" P62879 7 100673567-100679174 "Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010032, HPA040736" Approved Supported "Plasma membrane" NA NA 940000 "Cluster 52: Eosinophils - Transcription" "Cluster 72: Non-specific - Transcription" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "CAB010032: AB_2263466, HPA040736: AB_2677106" "unprognostic (1.55e-1)" "unprognostic (5.76e-2)" "unprognostic (1.01e-3)" "unprognostic (2.76e-1)" "unprognostic (1.11e-2)" "unprognostic (1.94e-1)" "unprognostic (3.68e-3)" "unprognostic (3.52e-1)" "unprognostic (6.58e-2)" "unprognostic (2.54e-1)" "unprognostic (9.79e-3)" "unprognostic (1.70e-1)" "unprognostic (3.75e-2)" "unprognostic (1.24e-1)" "unprognostic (3.19e-1)" "unprognostic (5.29e-2)" "unprognostic (2.98e-1)" 198.4 211.0 131.4 128.3 137.3 207.5 188.0 112.3 179.6 209.4 103.8 168.0 103.2 182.4 63.7 328.4 179.8 105.5 175.9 130.2 138.1 186.1 185.8 210.1 107.9 140.3 130.1 175.3 184.8 98.9 203.3 107.4 123.6 183.0 83.6 20.1 190.8 113.6 175.9 295.5 143.5 113.5 126.3 225.9 172.4 92.9 137.6 90.2 144.8 90.2 105.7 165.2 217.7 120.7 358.6 268.6 222.7 272.5 169.8 199.9 194.3 208.4 288.4 294.3 241.7 205.3 333.7 157.7 216.0 311.3 332.2 243.0 177.7 312.6 103.0 216.9 152.1 120.8 198.7 171.3 282.4 157.7 254.5 259.5 291.1 304.2 244.6 237.6 343.6 132.5 228.6 303.3 270.4 980.0 249.5 450.3 173.5 225.1 290.1 234.3 136.3 253.8 235.4 291.3 241.0 380.1 278.0 449.2 201.3 125.3 192.4 192.1 325.8 313.8 346.8 619.2 266.6 88.8 111.9 240.9 237.1 349.7 443.6 27.6 28.6 70.9 17.5 42.7 16.2 13.6 17.9 15.4 28.1 18.1 11.8 12.4 117.2 15.4 35.9 23.8 23.5 12.5 131.4 137.3 112.3 179.6 130.2 138.1 140.3 130.1 123.6 126.3 137.6 120.7 138.1 57.7 97.0 16.0 104.1 151.8 159.3 72.9 148.0 10.4 105.4 106.0 35.0 100.1 55.5 84.6 4.2 172.4 89.4 285.4 162.4 163.7 32.6 133.5 106.8 136.5 180.4 127.7 12.7 218.7 312.1 117.6 135.1 127.2 44.4 97.6 126.0 69.9 264.4 72.3 10.8 211.2 75.3 198.6 198.8 20.1 144.8 193.5 140.5 15.9 160.8 128.2 96.8 5.0 6.9 257.1 285.6 130.1 122.5 226.5 162.3 107.0 68.3 8.5 65.7 62.0 162.2 34.3 69.6 240.7 194.8 293.9 117.8 88.1 192.2 259.5 GNB4 ENSG00000114450 "G protein subunit beta 4" Q9HAV0 3 179396088-179451476 "Disease related genes, Human disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 81.1;Kupffer cells: 98.1;Macrophages: 66.8;Microglial cells: 91.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 143.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018383, CAB018737, HPA040736" Supported Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 44: HDLM-2 - Immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB018383: AB_631542, CAB018737: AB_640712, HPA040736: AB_2677106" "unprognostic (2.56e-2)" "unprognostic (1.95e-1)" "unprognostic (1.62e-1)" "unprognostic (1.01e-1)" "unprognostic (5.97e-3)" "unprognostic (2.12e-1)" "unprognostic (1.44e-2)" "unprognostic (8.28e-2)" "unprognostic (1.16e-1)" "unprognostic (3.44e-1)" "unprognostic (1.56e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (1.39e-6)" "unprognostic (1.90e-3)" "unprognostic (3.13e-2)" "unprognostic (8.90e-2)" "unprognostic (2.80e-3)" 14.9 6.3 8.7 21.9 19.2 33.7 12.4 7.3 11.2 11.5 2.9 9.5 5.9 9.2 3.7 21.9 7.0 15.2 13.9 9.6 8.7 5.9 7.8 16.0 17.7 15.5 8.5 5.8 2.8 2.7 3.0 21.8 14.5 4.5 8.6 2.0 4.7 4.0 3.1 34.1 6.4 23.5 14.5 18.1 7.4 4.3 10.9 7.9 6.3 5.7 11.5 13.2 6.8 19.7 33.4 15.4 37.7 0.8 23.8 41.5 44.1 46.7 33.1 54.1 61.3 0.8 3.7 61.6 9.9 54.3 49.7 0.6 36.4 43.1 56.7 143.6 29.2 71.3 54.9 0.7 23.4 62.3 16.2 32.9 6.6 42.4 21.6 12.0 59.3 13.7 18.7 0.8 42.8 1.3 32.8 24.3 18.9 0.2 19.3 61.4 49.2 25.3 34.9 1.9 7.0 20.5 37.5 33.0 61.1 23.0 67.5 26.1 45.3 45.1 27.4 13.6 61.6 0.3 0.9 0.8 24.7 52.8 35.4 5.6 21.3 11.0 0.2 27.8 0.1 6.7 0.4 0.3 24.9 13.6 0.4 0.3 14.5 3.4 23.5 12.8 0.6 8.8 8.7 19.2 7.3 11.2 9.6 8.7 15.5 8.5 14.5 14.5 10.9 19.7 40.0 25.6 12.8 17.9 20.1 18.7 1.8 2.5 13.6 1.7 14.3 12.3 15.6 0.0 12.3 3.7 6.2 13.8 11.5 0.1 3.9 1.1 1.2 15.6 22.9 42.9 0.0 22.9 18.6 1.6 18.7 26.6 3.6 10.8 10.8 16.2 53.2 0.9 81.1 1.7 18.4 0.0 2.0 98.1 17.4 1.4 10.2 66.8 14.2 91.8 59.9 0.8 2.1 11.6 7.7 2.8 0.0 15.8 8.1 2.6 0.2 0.2 11.3 4.0 26.3 9.9 41.8 2.3 16.8 23.4 25.4 4.1 2.9 14.7 0.0 1.3 GP6 GPVI ENSG00000088053 "Glycoprotein VI platelet" Q9HCN6 19 55013705-55038264 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Blood coagulation, Hemostasis" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 6.2;Early spermatids: 14.3;Excitatory neurons: 9.9;Inhibitory neurons: 10.2;Late spermatids: 8.7;Macrophages: 10.3" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 13 "HEL: 9.4;K-562: 4.1;U-2 OS: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA047611, HPA066482" Approved Supported "Plasma membrane" "Intracellular and membrane" NA NA 44000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 71: Testis - DNA repair" "Cluster 36: HEL - Hemostasis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "HPA047611: , HPA066482: AB_2685674" "unprognostic (3.06e-3)" "unprognostic (4.58e-2)" "unprognostic (1.74e-5)" "unprognostic (1.94e-1)" "unprognostic (1.20e-1)" "unprognostic (3.52e-2)" "unprognostic (7.50e-4)" "unprognostic (2.81e-1)" "unprognostic (1.00e-1)" "unprognostic (4.18e-2)" "unprognostic (3.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.53e-1)" "unprognostic (2.62e-1)" "unprognostic (3.32e-2)" "unprognostic (5.44e-3)" "unprognostic (2.70e-2)" 0.1 0.0 0.1 0.0 0.1 0.9 0.2 0.7 0.5 0.5 0.0 0.2 0.0 0.2 0.0 1.4 0.4 0.0 0.7 0.1 0.0 0.5 0.2 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.3 0.1 0.1 0.4 0.0 0.2 0.4 0.1 0.1 1.2 0.1 0.0 0.0 0.9 0.2 2.7 0.0 0.0 0.4 0.0 0.0 0.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.4 0.1 0.0 0.1 0.1 0.3 9.4 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 2.5 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 1.2 0.1 0.1 0.7 0.5 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 3.6 0.0 0.0 0.3 0.3 0.0 2.0 0.3 0.4 0.7 1.5 0.3 0.0 6.2 0.1 0.4 0.7 0.0 0.1 14.3 1.4 0.4 1.2 0.0 0.0 9.9 0.4 0.3 0.6 0.0 2.2 1.3 0.8 3.3 0.2 0.1 3.3 10.2 0.0 0.0 0.8 0.2 8.7 0.3 10.3 0.0 1.0 0.3 0.4 2.1 1.5 1.5 0.2 0.1 0.0 0.0 0.4 0.1 0.0 1.9 2.6 0.0 0.4 0.2 1.4 1.2 0.0 0.1 0.5 0.4 0.0 0.3 0.7 GPC3 "DGSX, OCI-5, SDYS, SGB, SGBS, SGBS1" ENSG00000147257 "Glypican 3" P51654 X 133535745-133985594 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Protease inhibitor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "placenta: 574.9" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 65.1;Extravillous trophoblasts: 61.0;Fibroblasts: 404.2;Muller glia cells: 88.9;Syncytiotrophoblasts: 148.6" "Cancer enriched" "Detected in all" 4 "liver cancer: 269.0" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "naive CD4 T-cell: 1.8;naive CD8 T-cell: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.8" "Group enriched" "Detected in some" 5 "HAP1: 514.3;Hep G2: 1825.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006316 Supported "Plasma membrane" NA NA 27000 "Cluster 32: T-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA006316: AB_1078994" "unprognostic (2.06e-1)" "unprognostic (2.36e-1)" "unprognostic (9.51e-2)" "unprognostic (4.17e-2)" "unprognostic (1.78e-1)" "unprognostic (1.46e-1)" "unprognostic (6.10e-2)" "unprognostic (1.17e-2)" "unprognostic (2.07e-2)" "unprognostic (3.92e-3)" "unprognostic (6.06e-2)" "unprognostic (1.71e-1)" "unprognostic (3.81e-3)" "prognostic unfavorable (4.83e-4)" "unprognostic (1.43e-1)" "unprognostic (2.21e-1)" "unprognostic (1.60e-1)" 99.9 22.8 0.5 3.5 1.0 0.0 61.8 0.5 0.3 11.8 0.2 6.5 1.6 9.2 41.1 6.7 13.9 13.7 24.5 0.3 4.0 87.0 5.1 122.9 2.5 1.9 3.1 15.5 21.2 4.1 47.0 574.9 3.0 8.3 4.1 6.2 13.7 9.2 4.5 18.0 5.6 7.3 1.7 3.7 13.6 2.8 2.0 8.0 22.4 28.6 10.9 14.6 9.3 1.0 0.0 0.0 21.8 1.7 0.7 0.1 0.0 0.0 0.0 0.0 0.0 154.0 0.0 0.0 0.1 0.1 0.0 0.0 514.3 0.4 0.0 0.0 22.6 0.0 0.9 1825.2 0.3 0.0 0.5 12.9 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.5 0.1 132.1 0.1 0.0 0.0 0.0 0.1 122.4 6.1 15.3 40.3 0.0 0.0 0.4 233.8 0.5 23.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 1.8 1.2 0.0 0.7 0.0 0.0 0.0 0.1 0.5 1.0 0.5 0.3 0.3 4.0 1.9 3.1 3.0 1.7 2.0 1.0 28.5 0.0 1.7 0.3 1.0 10.5 4.8 17.0 0.0 0.4 5.0 10.4 0.5 1.5 20.0 5.5 0.0 65.1 0.8 0.5 19.6 0.3 0.9 0.2 0.4 1.8 1.8 0.0 2.5 1.6 61.0 404.2 0.5 1.5 0.0 1.0 2.2 0.0 26.7 0.0 2.5 3.1 2.0 0.0 6.1 2.4 10.5 1.0 3.6 23.4 0.0 88.9 0.0 3.5 1.4 1.7 2.6 3.0 0.4 2.7 1.2 40.7 24.3 3.1 0.0 21.7 21.3 6.9 7.1 0.2 4.0 148.6 1.1 7.6 4.1 0.6 GPR148 PGR6 ENSG00000173302 "G protein-coupled receptor 148" Q8TDV2 2 130729070-130730336 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046655, HPA060527" Uncertain Supported "Plasma membrane" NA NA "Plasma membrane" "HPA046655: , HPA060527: AB_2684307" "unprognostic (7.16e-4)" "unprognostic (3.38e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.5 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.2 0.3 0.1 0.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPR156 "GABABL, PGR28" ENSG00000175697 "G protein-coupled receptor 156" Q8NFN8 3 120164645-120285222 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "testis: 2.7" "Group enriched" "Detected in some" 4 "Astrocytes: 15.0;Early spermatids: 8.3;Late spermatids: 17.9;Oligodendrocyte precursor cells: 13.0" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "fHDF/TERT166: 1.3;PC-3: 1.3;SiHa: 3.5;U-2 OS: 1.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA028642, HPA028644" Uncertain Supported "Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 20: HeLa - Mitochondria" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA028642: AB_10599711, HPA028644: AB_10600441" "unprognostic (2.85e-3)" "unprognostic (1.02e-1)" "unprognostic (3.53e-3)" "unprognostic (2.02e-3)" "unprognostic (1.07e-1)" "unprognostic (3.79e-1)" "unprognostic (2.62e-4)" "unprognostic (2.03e-1)" "unprognostic (4.54e-4)" "unprognostic (5.03e-2)" "unprognostic (1.57e-1)" "unprognostic (1.10e-1)" "unprognostic (4.03e-5)" "unprognostic (2.43e-2)" "unprognostic (3.43e-2)" "unprognostic (4.91e-3)" "unprognostic (6.71e-2)" 0.0 0.0 0.3 0.1 0.3 0.0 0.3 0.0 0.2 0.2 0.1 0.0 0.0 0.4 0.0 0.2 1.0 0.1 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.3 0.3 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.4 0.7 0.4 0.0 0.0 0.0 0.4 0.3 0.0 0.0 2.7 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.3 0.0 0.3 0.5 0.0 0.2 0.0 0.3 1.3 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.3 0.1 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.4 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.4 0.6 3.5 0.0 0.4 0.1 0.4 0.0 0.1 0.1 1.9 0.0 0.1 0.4 0.2 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.2 0.2 0.1 0.3 0.3 0.1 0.3 0.1 0.3 0.0 0.0 0.0 15.0 0.0 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 8.3 0.3 0.2 0.0 0.0 0.0 1.5 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 17.9 0.0 0.1 0.0 1.0 0.0 1.3 0.0 13.0 2.9 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.1 0.6 1.4 0.0 0.0 0.1 0.0 0.3 0.0 0.0 GPR160 "GPCR1, GPCR150" ENSG00000173890 "G protein-coupled receptor 160" Q9UJ42 3 170037995-170085392 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 107.9;parathyroid gland: 216.6" "Cell type enhanced" "Detected in many" "Enteroendocrine cells: 194.8;Proximal enterocytes: 362.1;Proximal tubular cells: 151.4;Rod photoreceptor cells: 153.2;Undifferentiated cells: 199.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPMI-8226: 123.9;SK-BR-3: 95.8;THP-1: 197.2;U-266/70: 206.2;U-266/84: 127.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA006970 Approved Supported "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA006970: AB_1849275" "unprognostic (1.70e-1)" "unprognostic (5.08e-3)" "unprognostic (2.96e-2)" "unprognostic (2.39e-3)" "unprognostic (2.20e-1)" "unprognostic (3.01e-1)" "unprognostic (5.21e-2)" "prognostic favorable (1.21e-4)" "unprognostic (5.71e-3)" "unprognostic (1.35e-1)" "unprognostic (4.35e-2)" "unprognostic (1.77e-1)" "prognostic favorable (4.93e-7)" "unprognostic (1.40e-1)" "unprognostic (2.25e-1)" "unprognostic (1.43e-1)" "prognostic favorable (3.61e-4)" 12.2 1.7 0.7 15.9 1.0 107.9 22.5 1.0 1.6 11.2 0.9 72.0 73.8 5.8 57.9 2.9 5.4 18.6 1.0 0.6 0.7 59.8 4.1 15.0 27.9 1.4 0.9 0.6 18.4 216.6 1.4 4.1 1.1 26.7 72.6 104.7 19.3 6.3 1.3 1.2 98.6 4.4 0.8 25.2 43.0 5.2 0.9 9.5 6.7 2.7 30.4 26.8 1.0 1.2 64.2 1.5 0.3 0.5 0.3 0.4 15.6 0.4 0.5 0.4 1.9 11.7 8.1 29.4 12.9 0.6 4.0 0.7 8.8 0.5 1.0 45.9 17.7 19.1 1.0 24.3 0.2 38.2 24.8 0.2 0.9 2.0 2.3 2.8 1.4 13.7 6.4 73.9 0.4 41.5 2.9 8.4 10.3 39.1 2.4 5.3 1.1 123.9 32.3 86.8 6.1 1.8 0.8 95.8 4.5 8.2 55.9 197.2 1.9 0.2 0.4 7.1 4.8 206.2 127.9 51.4 0.8 40.3 2.8 2.9 1.1 9.3 0.5 0.4 1.0 8.0 1.0 0.4 2.4 12.3 3.0 1.1 11.3 0.4 0.2 3.2 0.3 1.2 0.7 1.0 1.0 1.6 0.6 0.7 1.4 0.9 1.1 0.8 0.9 1.2 35.2 9.6 51.1 0.7 25.9 0.4 3.2 4.1 0.0 9.5 48.5 18.3 1.0 28.6 22.7 62.5 39.6 3.1 11.6 88.9 54.8 10.3 33.7 20.6 4.4 8.7 194.8 0.4 1.5 72.0 21.1 1.0 50.0 54.0 1.3 0.1 20.0 0.9 7.4 15.2 0.6 133.9 18.3 11.7 11.2 36.3 0.6 17.0 28.4 7.5 62.3 16.6 0.0 1.0 0.9 60.3 118.6 0.4 56.8 25.4 362.1 151.4 27.9 153.2 0.0 0.8 1.4 7.4 13.1 0.9 0.9 27.2 4.2 1.2 199.7 35.5 GRID2IP ENSG00000215045 "Grid2 interacting protein" A4D2P6 7 6497462-6551436 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enriched" "Detected in single" 34 "brain: 31.9" "Cell type enhanced" "Detected in some" "Excitatory neurons: 2.8;Inhibitory neurons: 2.9;Oligodendrocyte precursor cells: 4.5" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "thalamus: 31.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 4 "REH: 3.6" "Group enriched" "Detected in many" 5 "cerebellum: 22.4;thalamus: 7.2" "Low region specificity" "Detected in all" HPA045381 Approved "Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA045381: AB_10962495" "unprognostic (1.77e-1)" "unprognostic (2.64e-1)" "unprognostic (3.39e-4)" "unprognostic (1.19e-3)" "unprognostic (5.52e-2)" "unprognostic (2.50e-2)" "unprognostic (2.82e-1)" "unprognostic (2.37e-2)" "unprognostic (1.92e-3)" "unprognostic (2.06e-3)" "unprognostic (1.64e-1)" "unprognostic (3.40e-2)" "unprognostic (3.38e-2)" "unprognostic (5.54e-2)" "unprognostic (8.08e-2)" "unprognostic (1.87e-1)" "unprognostic (3.17e-1)" 0.0 0.4 6.7 0.1 6.2 0.2 0.2 10.7 1.4 0.1 0.0 0.3 0.4 0.1 0.0 0.3 0.2 0.1 0.1 0.1 7.9 0.2 0.0 0.2 0.1 2.4 9.8 0.1 0.5 0.5 0.9 0.0 1.9 0.5 0.1 0.5 0.4 0.3 0.0 0.7 0.3 0.0 0.0 0.3 0.4 0.3 31.9 0.2 0.3 0.0 0.1 0.1 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.3 0.0 3.6 0.1 0.1 0.0 0.1 0.0 0.4 0.0 0.3 0.0 0.1 0.8 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 10.7 1.4 0.1 7.9 2.4 9.8 1.9 0.0 31.9 0.2 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.6 0.1 0.2 0.1 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.5 0.5 0.1 0.0 0.1 0.0 0.4 2.8 0.0 0.1 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 4.5 1.3 0.1 0.0 0.0 0.3 0.2 0.4 0.1 0.0 1.0 0.0 0.0 0.1 0.8 0.2 1.2 0.0 0.0 0.1 0.9 0.1 0.2 GRPR "BB2, BB2R" ENSG00000126010 "Gastrin releasing peptide receptor" P30550 X 16123565-16153518 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "pancreas: 20.3" "Cell type enriched" "Detected in single" 15 "Inhibitory neurons: 6.3" "Cancer enriched" "Detected in some" 4 "breast cancer: 6.6" "Region enhanced" "Detected in some" "hypothalamus: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "PC-3: 29.2;T-47d: 38.2;U-138 MG: 51.5" "Region enhanced" "Detected in single" "hypothalamus: 2.0" "Low region specificity" "Detected in all" HPA069604 Supported "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 25: Pancreas - Digestion" "Cluster 6: T47d - Mammary gland" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA069604: AB_2686158" "unprognostic (3.32e-2)" "unprognostic (1.97e-1)" "unprognostic (1.72e-1)" "unprognostic (9.24e-2)" "unprognostic (2.87e-1)" "unprognostic (9.17e-2)" "unprognostic (5.06e-2)" "unprognostic (2.82e-1)" "unprognostic (1.01e-1)" "unprognostic (3.68e-3)" "unprognostic (2.62e-1)" "unprognostic (1.57e-1)" "unprognostic (5.59e-2)" "unprognostic (2.15e-2)" "unprognostic (2.56e-1)" "unprognostic (2.92e-1)" "unprognostic (2.86e-2)" 0.1 0.1 0.1 0.2 0.2 0.1 1.9 0.0 0.3 0.3 0.1 0.4 0.1 0.5 1.9 0.0 0.1 0.1 0.2 0.2 1.6 0.0 0.0 0.1 0.1 0.3 0.0 0.0 20.3 0.2 0.0 0.1 0.2 0.5 0.3 0.1 0.0 0.1 0.2 0.0 0.1 0.8 1.1 0.1 1.1 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.1 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.7 0.3 0.0 0.9 0.1 4.0 1.6 0.4 0.1 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 1.2 0.5 0.0 0.0 0.0 0.5 0.0 29.2 0.0 0.1 0.1 0.1 0.0 0.8 0.1 0.0 0.1 0.1 1.5 38.2 0.1 0.2 51.5 1.9 0.0 1.6 0.3 0.2 0.2 0.0 0.1 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.2 1.6 0.3 0.0 0.2 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GUCA1A "C6orf131, COD3, CORD14, dJ139D8.6, GCAP, GCAP1, GUCA, GUCA1" ENSG00000048545 "Guanylate cyclase activator 1A" P43080 6 42155406-42181338 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 91 "retina: 804.8" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 667.2;Late spermatids: 432.4;Muller glia cells: 219.9;Rod photoreceptor cells: 1191.6" "Cancer enriched" "Detected in single" 9 "testis cancer: 3.5" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 10 "plasmacytoid DC: 4.9" "Lineage enriched" "Detected in single" 10 "dendritic cells: 4.9" "Group enriched" "Detected in some" 8 "NTERA-2: 3.8;SH-SY5Y: 4.5" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA005561, HPA075056" Enhanced Approved "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 5: NTERA-2 - Transcription" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA005561: AB_2667361, HPA075056: " "unprognostic (1.91e-2)" "unprognostic (3.92e-3)" "unprognostic (2.49e-2)" "unprognostic (9.16e-2)" "unprognostic (1.04e-4)" "unprognostic (9.70e-2)" "unprognostic (6.71e-3)" "unprognostic (1.89e-1)" "unprognostic (1.59e-2)" "unprognostic (3.08e-3)" "unprognostic (2.79e-1)" "unprognostic (1.51e-1)" "unprognostic (1.54e-1)" "unprognostic (1.16e-1)" 0.0 0.0 1.5 0.1 3.5 0.1 0.0 0.9 1.8 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 5.4 0.0 0.0 0.0 0.1 1.5 1.4 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 804.8 0.0 0.0 0.1 0.1 0.1 0.1 0.8 0.0 0.0 8.8 6.2 0.0 0.0 0.0 0.2 0.0 0.1 1.2 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.1 0.5 0.0 0.0 4.9 0.0 0.0 1.5 3.5 0.9 1.8 1.3 5.4 1.5 1.4 1.4 0.8 6.2 1.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 140.7 0.0 0.0 0.3 0.0 0.0 0.0 667.2 0.6 1.3 0.0 0.0 0.0 106.5 0.0 0.0 8.2 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.0 0.5 0.0 0.0 0.2 65.6 1.0 0.0 4.1 0.0 0.0 432.4 1.8 0.1 0.0 0.0 5.2 219.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 1191.6 0.0 0.0 1.2 3.2 3.9 0.0 0.0 0.3 0.0 0.1 0.0 0.1 GYPC "CD236, CD236R, Ge, GPC, GYPD" ENSG00000136732 "Glycophorin C (Gerbich blood group)" P04921 2 126656133-126696667 "Blood group antigen proteins, CD markers, Predicted membrane proteins" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 441.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 1728.6;Hofbauer cells: 488.7" "Cancer enhanced" "Detected in all" "melanoma: 66.9" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HHSteC: 433.1;K-562: 362.1;SK-MEL-30: 668.4;U-266/70: 363.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008965, CAB009445" Enhanced Supported "Plasma membrane" NA NA 970000 "Cluster 20: T-cells - T-cell receptor" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "CAB009445: AB_2116251, HPA008965: AB_1078455" "unprognostic (1.63e-2)" "unprognostic (7.14e-3)" "unprognostic (8.39e-2)" "unprognostic (3.31e-3)" "unprognostic (4.19e-2)" "unprognostic (1.69e-2)" "unprognostic (8.82e-2)" "unprognostic (3.52e-1)" "unprognostic (1.19e-1)" "unprognostic (2.21e-1)" "unprognostic (1.25e-1)" "unprognostic (1.11e-1)" "unprognostic (2.05e-2)" "unprognostic (2.73e-2)" "unprognostic (1.51e-1)" "unprognostic (2.29e-1)" "unprognostic (8.00e-3)" 172.3 73.0 17.3 51.5 17.6 441.0 109.2 17.5 30.8 75.7 20.2 89.1 18.2 62.3 20.2 42.3 68.4 56.3 161.9 16.5 20.2 58.4 18.5 101.4 110.5 22.2 18.4 91.5 34.8 9.6 16.9 50.3 22.0 46.5 19.3 10.3 26.4 56.1 212.7 37.0 52.9 55.9 20.6 98.5 41.0 7.3 23.6 59.6 33.3 204.1 75.9 73.0 54.4 24.9 1.3 0.0 152.0 0.2 116.1 100.5 0.2 24.0 186.4 28.9 84.9 0.0 0.2 0.6 0.4 69.6 107.6 0.3 85.7 0.1 9.5 79.7 0.0 279.0 0.0 0.0 433.1 99.0 0.7 237.4 0.0 23.1 0.1 2.3 1.0 190.4 362.1 214.6 70.5 0.0 0.1 148.9 46.7 0.0 0.4 18.1 12.1 0.4 11.8 0.0 0.2 0.0 0.3 0.0 668.4 20.7 0.0 258.5 65.7 107.3 1.0 7.3 1.2 363.9 257.4 0.5 51.4 135.8 99.3 0.8 28.6 2.2 153.1 40.3 172.2 95.8 136.7 186.5 50.0 102.6 190.5 188.3 21.9 81.1 24.7 27.1 179.4 119.0 17.3 17.6 17.5 30.8 16.5 20.2 22.2 18.4 22.0 20.6 23.6 24.9 260.7 6.4 7.7 0.7 152.7 38.0 3.4 17.0 43.3 0.6 14.6 110.5 34.9 84.4 6.0 14.7 2.1 4.9 194.0 0.0 135.0 202.9 1.6 3.6 99.8 157.2 0.0 1728.6 0.4 4.9 6.9 170.5 10.2 2.5 22.9 23.3 229.2 6.2 488.7 0.0 0.5 1.1 0.0 118.0 108.5 4.9 87.3 134.9 305.9 15.0 98.0 5.1 204.9 6.0 0.1 6.0 0.4 69.2 250.9 9.4 0.0 8.1 1.7 2.6 59.2 65.8 88.6 0.2 0.7 41.9 26.6 9.0 228.0 31.8 1.6 2.9 HTRA1 "ARMD7, HtrA, IGFBP5-protease, PRSS11" ENSG00000166033 "HtrA serine peptidase 1" Q92743 10 122458551-122514907 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Growth factor binding, Hydrolase, Protease, Serine protease" "Age-related macular degeneration, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 269.3;Granulosa cells: 731.6;Horizontal cells: 625.9;Muller glia cells: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 2417.8;ASC TERT1: 889.4;fHDF/TERT166: 862.3;HSkMC: 1581.4;LHCN-M2: 1238.2;U-87 MG: 1004.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036655 Approved Supported "Plasma membrane" "Secreted to blood" NA NA 24800000 7600000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA036655: AB_10671966" "unprognostic (3.84e-1)" "unprognostic (3.42e-2)" "unprognostic (1.57e-2)" "unprognostic (1.86e-2)" "unprognostic (1.22e-3)" "unprognostic (8.71e-3)" "unprognostic (2.33e-2)" "unprognostic (3.83e-1)" "unprognostic (7.22e-2)" "unprognostic (3.36e-2)" "unprognostic (1.32e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (7.90e-7)" "unprognostic (7.12e-3)" "unprognostic (9.13e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (5.62e-6)" 246.0 81.3 382.1 37.0 436.6 0.5 202.8 422.6 595.7 352.1 316.2 154.8 20.8 197.1 247.1 57.8 122.9 301.2 114.7 377.7 411.4 230.9 226.4 69.9 39.9 427.1 447.0 425.5 55.9 111.8 184.1 281.9 425.3 85.7 51.8 243.6 101.1 114.5 31.1 130.5 73.5 152.3 382.1 54.2 87.3 19.5 423.6 21.2 78.8 80.9 27.3 137.3 188.3 464.2 0.3 45.6 19.4 5.7 2417.8 889.4 0.8 108.3 196.8 44.4 23.6 0.2 0.6 0.0 29.0 862.3 68.6 12.8 7.6 124.4 6.2 0.1 4.9 0.1 65.4 0.3 123.7 0.1 0.9 1581.4 444.6 25.8 205.3 503.6 207.1 0.0 0.1 1.5 1238.2 22.3 0.1 0.7 20.9 0.2 67.6 0.2 1.3 0.4 282.6 2.2 1.2 3.9 272.1 0.2 122.2 91.4 8.6 0.2 136.0 309.9 4.5 141.3 94.1 0.2 0.1 0.3 1004.6 0.2 148.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 382.1 436.6 422.6 595.7 377.7 411.4 427.1 447.0 425.3 382.1 423.6 464.2 55.1 22.4 6.9 116.5 0.9 44.1 32.5 10.8 23.9 53.3 5.4 31.2 26.4 14.3 0.9 64.4 54.2 30.9 1.3 0.0 0.0 2.0 3.5 11.3 76.5 107.0 0.0 2.7 2.2 4.6 164.6 269.3 4.6 14.4 1.3 731.6 57.8 157.8 51.3 625.9 31.2 0.3 8.2 18.1 59.9 4.2 31.7 22.0 46.2 86.2 8.5 373.8 0.0 193.0 112.5 2.7 1.3 77.5 1.9 8.7 0.2 22.6 10.1 150.3 6.6 63.3 140.5 0.2 0.7 7.0 30.5 87.7 7.2 2.5 0.6 11.9 IFIT5 RI58 ENSG00000152778 "Interferon induced protein with tetratricopeptide repeats 5" Q13325 10 89414568-89421605 "Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity" "RNA-binding, tRNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 109.1;BJ hTERT+ SV40 Large T+ RasG12V: 128.0" "Low region specificity" "Detected in all" "HPA037957, HPA062180" Uncertain Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA037957: AB_10672499, HPA062180: AB_2684705" "unprognostic (2.17e-1)" "unprognostic (1.85e-1)" "unprognostic (1.38e-1)" "unprognostic (1.26e-1)" "unprognostic (1.67e-3)" "unprognostic (4.19e-2)" "unprognostic (2.88e-2)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (8.89e-2)" "unprognostic (1.63e-1)" "unprognostic (1.86e-1)" "unprognostic (3.24e-2)" "unprognostic (1.48e-1)" "unprognostic (3.42e-1)" "unprognostic (2.43e-2)" "unprognostic (1.73e-1)" 13.3 11.6 11.9 11.1 14.3 16.1 9.7 18.7 13.5 11.4 25.0 9.4 9.4 10.2 9.1 7.4 11.2 12.6 14.6 10.8 14.5 14.2 14.1 17.1 13.2 14.7 13.0 14.1 9.2 22.8 3.7 14.6 14.4 9.7 8.9 9.0 12.2 10.5 3.7 5.5 11.1 14.2 19.2 18.6 9.1 6.3 12.5 10.5 10.8 6.4 11.3 12.3 4.6 16.8 41.8 12.5 17.3 56.9 46.7 43.4 3.7 33.2 59.5 109.1 128.0 1.0 19.0 1.8 12.1 38.7 42.8 34.8 20.9 19.3 26.0 17.8 13.1 5.0 8.9 7.8 52.4 0.4 3.1 34.9 7.4 32.0 23.7 30.8 6.2 10.8 0.0 29.4 30.8 7.7 12.6 3.8 2.2 0.0 21.9 11.0 20.0 4.6 23.7 5.1 1.9 11.1 18.2 6.6 51.6 4.7 6.2 3.5 15.5 14.0 10.3 23.2 20.0 3.8 0.6 0.2 24.2 3.3 11.6 24.7 15.7 19.3 13.9 25.6 16.4 21.4 14.7 13.0 14.2 18.1 16.8 14.1 45.2 8.3 32.1 1.3 14.1 12.3 11.9 14.3 18.7 13.5 10.8 14.5 14.7 13.0 14.4 19.2 12.5 16.8 24.8 6.4 14.8 3.6 12.8 8.5 35.7 15.2 13.6 8.3 4.4 4.3 8.9 11.5 12.4 9.2 0.0 6.3 7.5 7.2 11.7 13.7 0.1 11.2 17.1 23.1 4.9 2.1 3.6 9.1 11.5 17.9 6.1 13.3 15.2 6.2 12.1 16.5 11.0 35.3 7.2 5.5 6.1 8.9 6.0 1.0 21.1 10.8 7.2 4.7 12.3 14.6 7.2 4.5 10.2 10.5 5.9 17.3 6.8 21.0 7.5 17.0 9.6 5.3 19.7 15.4 14.2 17.2 14.4 7.7 3.8 4.5 9.3 4.7 2.5 29.1 IFNGR1 "CD119, IFNGR" ENSG00000027697 "Interferon gamma receptor 1" P15260 6 137197485-137219449 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 867.1;Club cells: 405.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025889, HPA029213, HPA063871" Approved Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB025889: , HPA029213: AB_10601023, HPA063871: AB_2685138" "unprognostic (1.73e-1)" "unprognostic (8.86e-2)" "unprognostic (9.85e-3)" "unprognostic (1.71e-1)" "unprognostic (6.55e-2)" "unprognostic (1.25e-1)" "unprognostic (4.05e-1)" "unprognostic (6.97e-2)" "unprognostic (9.86e-2)" "unprognostic (1.57e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "prognostic unfavorable (5.48e-4)" "unprognostic (1.58e-1)" "unprognostic (2.87e-2)" "unprognostic (1.81e-2)" "unprognostic (5.38e-3)" 155.5 59.3 54.6 131.5 57.8 146.2 121.4 64.5 72.1 74.1 56.8 74.7 97.9 58.1 67.4 65.0 55.7 88.4 103.7 53.1 59.9 44.4 104.0 153.8 140.2 71.9 60.3 43.3 44.5 47.4 26.3 86.1 75.9 53.2 74.4 40.4 57.7 57.4 58.3 66.2 101.2 75.9 69.2 165.9 51.3 27.9 59.9 69.2 58.3 75.5 135.2 112.6 58.0 85.0 23.2 23.4 25.1 33.4 166.8 86.7 23.0 67.0 90.0 38.0 53.3 148.7 39.8 24.5 99.2 36.1 55.1 130.0 24.1 62.6 51.5 49.4 37.4 36.1 23.3 192.9 97.3 112.9 46.6 195.9 232.6 33.3 51.4 36.1 48.7 29.1 32.0 34.9 29.2 27.7 17.7 47.0 22.0 191.9 18.6 51.3 28.4 32.1 65.5 104.4 27.4 39.5 77.3 41.9 57.5 47.8 15.5 68.7 71.1 36.2 27.7 48.5 31.8 25.3 25.5 23.8 19.4 69.2 36.5 158.6 518.4 356.3 106.9 502.6 224.7 91.3 60.0 90.0 309.4 98.3 39.2 43.1 736.0 48.4 375.6 85.1 48.0 519.3 54.6 57.8 64.5 72.1 53.1 59.9 71.9 60.3 75.9 69.2 59.9 85.0 298.7 80.1 59.9 21.5 76.4 127.6 177.6 867.1 84.2 15.4 49.8 37.3 49.6 37.1 405.7 27.6 12.5 78.5 240.8 111.0 7.9 74.2 11.6 91.4 52.7 110.7 13.1 25.7 21.4 101.4 67.1 94.7 33.6 112.8 63.3 10.3 62.8 56.5 149.8 10.1 24.2 25.5 270.6 326.2 220.0 6.1 44.1 261.7 49.8 147.1 138.4 23.5 52.5 25.1 44.9 76.0 57.6 49.2 74.5 129.6 82.0 17.2 150.6 28.1 13.1 45.7 75.7 14.6 22.4 47.3 113.2 209.9 121.5 48.3 33.9 140.2 IFT52 "C20orf9, CGI-53, dJ1028D15.1, NGD2, NGD5" ENSG00000101052 "Intraflagellar transport 52" Q9Y366 20 43590937-43647299 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063367, HPA067423" Enhanced Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 89: Fibroblasts - ECM organization" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA063367: , HPA067423: AB_2685837" "unprognostic (2.88e-1)" "unprognostic (2.44e-2)" "unprognostic (6.82e-2)" "unprognostic (5.18e-3)" "unprognostic (7.39e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.30e-6)" "unprognostic (8.36e-2)" "unprognostic (1.25e-1)" "unprognostic (2.00e-1)" "unprognostic (2.98e-2)" "unprognostic (2.28e-2)" "unprognostic (3.43e-2)" "unprognostic (7.51e-2)" "prognostic favorable (3.33e-4)" "unprognostic (2.37e-1)" "unprognostic (7.40e-2)" 23.5 15.1 12.2 11.7 12.6 29.1 26.1 12.4 15.2 29.3 14.3 16.3 9.2 27.4 29.0 14.8 38.0 19.0 11.8 12.5 13.5 20.5 7.8 16.9 18.3 12.3 12.8 39.2 15.7 22.5 16.5 17.5 12.8 17.5 17.8 15.1 13.6 23.8 4.7 15.5 11.2 24.3 13.3 15.7 12.2 31.8 14.1 22.8 31.3 9.0 18.9 19.5 18.0 14.2 33.9 25.4 50.3 35.8 41.9 46.4 23.9 20.8 46.1 53.6 51.6 70.5 33.7 18.8 32.8 42.6 43.4 27.7 21.3 37.3 58.6 15.6 20.0 24.8 16.2 65.9 51.4 33.4 16.4 37.8 40.2 34.9 27.0 39.0 42.7 41.4 21.3 26.1 39.9 34.0 46.4 51.5 28.4 22.2 24.9 48.6 57.5 27.8 41.8 32.9 38.8 45.3 63.6 46.7 52.2 25.3 21.8 45.1 26.9 47.3 35.1 26.3 31.1 25.3 26.9 32.8 56.8 24.0 34.8 8.0 22.0 16.8 18.4 20.9 15.0 17.5 14.7 17.5 28.4 15.3 15.4 16.0 6.3 17.4 26.2 21.5 18.6 17.3 12.2 12.6 12.4 15.2 12.5 13.5 12.3 12.8 12.8 13.3 14.1 14.2 21.1 6.4 13.1 11.4 13.7 13.0 12.8 22.4 12.0 11.5 14.1 19.2 2.9 11.5 13.2 7.3 0.0 19.9 16.0 14.8 19.6 26.1 78.4 32.1 19.4 18.1 9.5 23.4 20.5 22.2 19.7 25.3 8.2 10.5 14.5 26.7 23.2 2.6 19.4 8.4 22.5 11.0 14.2 18.2 13.9 20.9 28.6 13.3 17.8 12.2 21.3 22.6 18.6 14.6 25.7 14.8 10.1 38.4 13.5 5.9 5.5 18.3 49.0 12.8 13.1 23.9 24.8 57.3 18.5 12.2 14.9 9.6 12.1 30.4 10.3 10.5 IL12RB1 "CD212, IL12RB" ENSG00000096996 "Interleukin 12 receptor subunit beta 1" P42701 19 18058995-18098944 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.6" "Cell type enhanced" "Detected in some" "dendritic cells: 35.1;Kupffer cells: 13.9;NK-cells: 69.0;Plasma cells: 15.3;T-cells: 31.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 18.8;HDLM-2: 35.2;Karpas-707: 57.8;U-698: 15.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA074414 Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074414: AB_2686687" "unprognostic (7.70e-3)" "prognostic favorable (3.41e-4)" "unprognostic (9.08e-3)" "unprognostic (1.18e-4)" "unprognostic (2.91e-1)" "unprognostic (1.33e-3)" "unprognostic (2.27e-1)" "unprognostic (8.99e-2)" "unprognostic (1.65e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (2.94e-1)" "prognostic unfavorable (5.90e-5)" "unprognostic (1.49e-1)" "unprognostic (2.21e-2)" "unprognostic (4.34e-2)" "unprognostic (2.93e-2)" 2.1 1.2 1.0 15.2 1.8 9.3 0.9 1.0 2.1 1.0 1.7 3.1 4.5 0.7 0.8 1.6 0.8 3.5 0.7 1.1 1.1 0.9 2.2 5.8 24.6 2.5 1.5 0.6 0.5 1.3 0.5 1.6 2.3 0.8 2.9 0.5 1.7 0.6 0.7 1.6 7.0 1.9 1.1 16.2 4.1 0.8 2.3 6.6 0.7 0.2 14.1 4.0 0.5 3.7 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.1 0.5 1.0 0.3 2.2 18.8 0.1 0.2 0.7 0.3 0.0 0.0 0.0 35.2 0.2 2.2 0.6 0.3 1.0 0.9 3.1 0.1 0.0 0.5 0.0 0.2 0.1 5.1 0.3 57.8 0.0 0.2 9.7 0.3 0.1 0.1 0.0 6.7 0.1 0.8 0.0 0.1 0.4 0.0 0.2 0.2 0.2 0.1 0.4 9.7 0.4 0.5 0.4 0.2 0.2 6.6 11.0 15.2 0.6 12.1 1.1 8.5 12.5 9.2 50.9 34.7 64.0 11.5 34.8 41.7 14.7 9.1 19.3 34.0 14.7 40.9 34.0 8.1 53.0 24.3 1.0 1.8 1.0 2.1 1.1 1.1 2.5 1.5 2.3 1.1 2.3 3.7 0.5 0.0 3.0 0.3 9.6 0.3 2.1 0.1 0.6 0.0 0.3 0.5 1.0 1.5 0.6 0.0 0.0 0.2 35.1 0.1 0.0 0.0 0.5 0.5 0.2 0.5 0.0 5.2 0.8 0.0 0.8 0.7 3.1 0.7 4.5 0.0 0.4 0.1 6.4 0.0 0.4 0.0 0.0 13.9 4.0 0.0 0.0 11.7 0.0 3.7 11.9 0.0 69.0 0.0 2.6 0.1 0.0 0.0 15.3 0.5 0.4 0.2 0.2 0.0 0.0 0.7 0.3 0.4 0.1 0.0 0.9 0.1 31.5 0.0 0.2 1.3 IL12RB2 ENSG00000081985 "Interleukin 12 receptor subunit beta 2" Q99665 1 67307364-67398724 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.5;placenta: 7.0" "Cell type enhanced" "Detected in some" "dendritic cells: 8.4;Excitatory neurons: 22.5;Inhibitory neurons: 16.6;T-cells: 12.8" "Group enriched" "Detected in many" 4 "cervical cancer: 1.8;head and neck cancer: 2.5;melanoma: 5.6;renal cancer: 1.7" "Region enhanced" "Detected in many" "hippocampal formation: 4.5" "Immune cell enhanced" "Detected in many" "NK-cell: 21.3" "Group enriched" "Detected in many" 35 "NK-cells: 21.3;T-cells: 6.0" "Group enriched" "Detected in some" 9 "HMC-1: 4.6;SCLC-21H: 6.8;SK-MEL-30: 18.4;THP-1: 13.4" "Region enhanced" "Detected in single" "olfactory bulb: 1.4" "Low region specificity" "Detected in all" HPA024168 Uncertain Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA024168: AB_1851629" "unprognostic (1.32e-1)" "unprognostic (1.54e-3)" "unprognostic (2.09e-1)" "unprognostic (2.68e-2)" "unprognostic (2.82e-2)" "unprognostic (1.09e-3)" "unprognostic (2.37e-2)" "unprognostic (3.90e-2)" "unprognostic (1.10e-1)" "unprognostic (2.38e-2)" "unprognostic (1.39e-1)" "unprognostic (3.60e-2)" "unprognostic (1.08e-3)" "unprognostic (1.82e-1)" "unprognostic (4.69e-2)" "unprognostic (7.11e-3)" "unprognostic (1.90e-1)" 1.9 0.3 1.2 1.2 1.6 0.8 0.4 0.0 2.3 0.6 0.0 0.4 0.3 0.2 0.3 0.8 0.1 0.5 0.2 4.5 0.0 0.3 0.8 0.4 1.8 0.0 0.7 0.2 2.6 0.8 0.0 7.0 0.0 0.1 0.4 0.1 1.3 0.7 3.5 1.4 0.4 0.4 0.0 1.4 0.3 1.0 0.3 1.0 0.1 0.7 0.9 0.7 0.2 0.7 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 1.2 0.6 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.2 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.3 0.0 0.1 18.4 0.0 0.0 13.4 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 6.0 0.0 3.2 0.0 1.6 1.0 0.0 0.0 0.0 0.1 0.3 21.3 0.0 0.0 3.9 1.2 1.2 1.6 0.0 2.3 4.5 0.0 0.0 0.7 0.0 0.0 0.3 0.7 0.2 0.0 2.3 1.0 0.6 0.5 0.2 0.1 0.6 0.0 0.1 0.3 0.7 0.0 0.7 0.0 0.0 0.0 8.4 0.0 0.0 0.0 1.5 0.3 0.3 0.1 0.0 0.8 22.5 0.0 0.0 0.9 2.6 0.7 0.0 1.5 0.0 0.0 3.8 0.0 16.6 0.0 0.0 0.8 0.9 0.9 0.0 0.5 1.8 2.8 0.0 0.0 4.1 1.0 1.6 0.2 0.0 0.0 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 1.0 0.6 0.0 12.8 0.0 0.0 0.1 IL7R "CD127, IL7RA" ENSG00000168685 "Interleukin 7 receptor" P16871 5 35852695-35879603 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 183.7" "Group enriched" "Detected in many" 4 "monocytes: 271.8;T-cells: 973.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "gdT-cell: 102.1;MAIT T-cell: 369.5;memory CD4 T-cell: 213.8;memory CD8 T-cell: 151.1;naive CD4 T-cell: 179.5;naive CD8 T-cell: 124.6;NK-cell: 113.2" "Group enriched" "Detected in all" 33 "NK-cells: 113.2;T-cells: 369.5" "Cell line enhanced" "Detected in many" "BJ: 99.8;BJ hTERT+ SV40 Large T+: 87.7;fHDF/TERT166: 187.7;HBF TERT88: 168.3;REH: 406.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "CAB010215, HPA067550" Supported "Plasma membrane" "Intracellular and membrane" NA NA 610000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "CAB010215: AB_673727, HPA067550: " "unprognostic (2.93e-3)" "unprognostic (3.38e-2)" "unprognostic (3.82e-3)" "unprognostic (5.58e-3)" "unprognostic (3.06e-2)" "unprognostic (1.74e-1)" "unprognostic (2.51e-3)" "unprognostic (5.53e-2)" "unprognostic (1.12e-1)" "unprognostic (9.29e-3)" "unprognostic (1.43e-1)" "unprognostic (2.69e-1)" "unprognostic (1.76e-2)" "unprognostic (5.64e-2)" "unprognostic (3.27e-3)" "unprognostic (2.22e-1)" "unprognostic (1.78e-1)" 11.2 14.4 1.5 137.6 1.8 14.0 20.4 7.4 2.7 12.0 1.0 17.3 15.0 3.9 1.6 11.0 5.7 32.4 2.2 2.0 2.5 4.5 12.5 63.9 139.4 1.8 0.5 2.2 5.3 0.8 1.7 2.9 1.6 8.7 20.4 0.9 3.3 3.1 4.1 3.8 56.8 5.6 0.6 70.1 34.1 4.7 4.4 183.7 7.6 1.7 123.0 48.0 7.1 6.2 0.6 0.4 0.7 0.4 0.7 0.6 0.6 99.8 50.6 87.7 51.3 0.5 0.6 9.6 0.3 187.7 15.9 16.0 0.2 6.0 168.3 8.6 1.1 3.2 10.3 0.0 1.5 0.6 7.2 1.6 0.0 18.7 4.3 2.4 2.6 0.7 0.7 0.9 71.3 0.2 2.3 1.0 0.3 0.3 4.6 406.2 5.2 0.6 0.0 5.3 0.4 0.2 15.9 1.7 0.2 0.3 0.6 0.4 7.0 34.5 58.4 14.8 13.4 0.6 0.2 10.4 17.4 9.2 27.8 4.3 1.6 1.0 102.1 1.2 369.5 1.5 213.8 151.1 0.7 2.1 179.5 124.6 7.3 113.2 1.5 1.8 39.7 87.7 1.5 1.8 7.4 2.7 2.0 2.5 1.8 0.5 1.6 0.6 4.4 6.2 8.9 16.0 16.0 0.0 47.4 11.6 2.7 0.0 5.2 0.0 8.6 6.1 4.9 0.0 2.5 0.0 0.0 0.2 136.0 0.6 0.0 1.0 0.1 1.1 0.4 13.2 0.0 16.4 0.0 2.0 0.2 11.6 53.5 1.2 19.6 0.2 13.2 4.4 10.6 0.0 0.0 0.5 0.0 10.6 98.5 0.8 0.0 58.8 21.4 2.8 271.8 0.0 11.3 0.0 0.0 0.1 1.4 0.0 93.5 1.4 0.0 0.8 5.8 0.0 0.0 5.5 7.9 0.2 0.1 1.5 10.4 0.3 973.8 0.4 0.4 3.5 ILDR2 C1orf32 ENSG00000143195 "Immunoglobulin like domain containing receptor 2" Q71H61 1 166895711-166975540 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.8;retina: 10.6;testis: 8.8" "Cell type enhanced" "Detected in some" "Astrocytes: 22.9;Excitatory neurons: 45.0;Muller glia cells: 89.1;Oligodendrocyte precursor cells: 96.0" "Cancer enriched" "Detected in some" 5 "glioma: 4.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.8;JURKAT: 5.7;MOLT-4: 4.3;U-2 OS: 9.6;U-251 MG: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012545, HPA012815" Uncertain Approved "Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA012545: AB_2126894, HPA012815: " "unprognostic (9.14e-2)" "unprognostic (5.05e-2)" "unprognostic (8.27e-2)" "unprognostic (2.16e-1)" "unprognostic (5.89e-2)" "unprognostic (5.33e-2)" "unprognostic (2.89e-5)" "unprognostic (2.09e-1)" "unprognostic (8.55e-2)" "unprognostic (4.51e-2)" "unprognostic (1.52e-1)" "unprognostic (2.58e-1)" "unprognostic (9.17e-2)" "unprognostic (5.87e-3)" "unprognostic (4.92e-2)" "unprognostic (1.64e-1)" "unprognostic (1.36e-1)" 0.3 0.3 7.0 0.2 6.7 0.5 0.0 0.0 8.0 0.1 0.0 1.6 0.1 0.1 0.4 0.1 0.2 0.3 1.4 8.7 4.4 2.8 0.4 0.4 0.2 0.0 4.8 0.1 0.1 0.0 1.4 0.1 0.2 0.8 0.3 10.6 0.1 1.1 0.1 0.0 0.2 0.7 0.0 0.1 0.1 8.8 12.8 1.1 0.1 0.2 0.2 0.3 0.1 1.5 0.0 0.0 7.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.0 0.8 1.5 0.2 0.0 0.3 0.0 0.0 0.0 0.0 1.9 1.4 0.0 0.0 0.2 0.0 2.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.2 0.0 4.3 0.0 2.7 0.1 0.0 0.0 0.2 0.5 0.5 0.1 1.0 0.0 0.0 0.0 0.0 0.8 0.0 0.7 0.0 0.0 9.6 0.0 5.4 1.8 0.0 0.4 1.0 1.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 6.7 0.0 8.0 8.7 4.4 0.0 4.8 0.2 0.0 12.8 1.5 0.0 0.0 0.0 22.9 0.1 0.0 0.0 0.0 0.0 3.5 0.1 0.0 4.3 0.0 0.6 0.0 6.2 0.0 2.0 0.2 0.0 0.1 12.7 0.0 0.1 0.2 1.2 0.0 45.0 0.2 0.3 0.6 0.0 0.1 0.0 1.7 0.4 1.6 0.1 1.7 17.6 0.0 0.0 0.0 0.0 18.8 0.6 0.2 0.0 5.6 0.6 89.1 0.0 96.0 16.5 0.1 0.2 0.0 0.9 0.0 0.0 4.9 0.0 8.8 0.0 8.8 0.5 4.8 2.0 0.0 0.0 0.3 0.5 0.1 0.3 0.0 ITGA2B "CD41, CD41B, GP2B, PPP1R93" ENSG00000005961 "Integrin subunit alpha 2b" P08514 17 44372180-44389649 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 16.6;epididymis: 10.7;lymphoid tissue: 11.2" "Cell type enhanced" "Detected in many" "Early spermatids: 16.1;Erythroid cells: 43.5;granulocytes: 17.8;Late spermatids: 24.8;Macrophages: 23.0" "Cancer enhanced" "Detected in some" "testis cancer: 2.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 14 "basophil: 64.5" "Lineage enriched" "Detected in single" 75 "granulocytes: 64.5" "Group enriched" "Detected in some" 14 "HEL: 404.6;HMC-1: 631.7" "Not detected" "Not detected" "CAB018611, HPA031168, HPA031169, HPA031170, HPA031171" Enhanced Approved "Plasma membrane" NA NA 90000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB018611: AB_2265153, HPA031168: AB_10664706, HPA031169: AB_10669671, HPA031170: AB_10696214, HPA031171: AB_10669773" "unprognostic (6.11e-2)" "unprognostic (3.23e-2)" "unprognostic (1.23e-1)" "unprognostic (4.85e-2)" "unprognostic (1.59e-2)" "unprognostic (3.98e-3)" "unprognostic (4.23e-5)" "unprognostic (1.25e-1)" "unprognostic (1.33e-2)" "unprognostic (7.22e-2)" "unprognostic (2.97e-3)" "unprognostic (1.30e-1)" "unprognostic (8.83e-9)" "unprognostic (7.82e-2)" "unprognostic (1.85e-1)" "unprognostic (1.95e-1)" "unprognostic (2.25e-1)" 0.8 0.2 3.7 0.2 3.6 16.6 0.4 4.0 4.8 1.5 3.8 0.3 0.0 0.9 10.7 0.3 1.5 0.8 1.4 3.5 3.6 1.0 0.5 5.1 0.2 3.6 3.5 1.5 0.1 1.3 1.9 1.1 3.6 0.6 0.1 1.6 0.1 0.8 0.6 0.1 0.3 0.2 3.3 11.2 0.3 2.9 3.5 0.1 3.1 1.1 0.1 0.2 0.7 3.7 0.5 0.7 2.2 0.3 0.1 0.3 18.4 0.3 0.1 0.8 0.6 0.0 0.2 0.0 0.3 0.0 0.2 0.6 1.8 0.0 0.4 0.4 1.1 404.6 0.3 1.3 0.0 0.2 631.7 0.4 0.0 0.2 0.0 0.0 0.0 0.3 0.7 1.1 0.0 0.7 0.5 36.4 0.8 0.0 0.7 0.7 0.2 0.0 0.0 0.1 0.4 1.0 0.5 0.5 0.1 1.5 4.5 0.9 0.3 0.2 0.7 0.0 0.0 0.4 0.2 0.3 0.4 0.3 0.8 64.5 0.3 4.0 0.1 0.0 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 4.5 0.0 0.0 0.8 0.0 19.3 3.7 3.6 4.0 4.8 3.5 3.6 3.6 3.5 3.6 3.3 3.5 3.7 0.3 0.0 1.5 1.0 0.4 0.3 0.4 0.1 1.8 5.1 0.2 1.1 1.5 1.5 1.3 5.5 8.4 1.3 0.1 0.6 0.0 0.0 16.1 1.0 0.7 2.1 0.0 43.5 4.1 0.0 1.4 1.1 0.0 3.2 17.8 0.1 3.6 0.0 0.2 3.3 2.8 0.0 0.0 3.1 0.7 24.8 1.8 23.0 0.0 1.0 2.9 1.3 0.0 9.5 4.6 0.1 0.0 1.9 0.1 0.3 0.0 0.0 0.0 3.0 0.0 1.8 0.7 3.4 7.4 0.5 0.0 0.7 0.6 0.1 0.3 0.3 ITGA3 "CD49c, GAP-B3, MSK18, VCA-2, VLA3a" ENSG00000005884 "Integrin subunit alpha 3" P26006 17 50055968-50090481 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 111.9;Exocrine glandular cells: 105.1;Pancreatic endocrine cells: 245.6;Urothelial cells: 104.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 647.2;hTERT-RPE1: 572.8;RPTEC TERT1: 562.0;U-87 MG: 920.8;WM-115: 570.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008572, CAB018594" Enhanced Supported "Plasma membrane" NA NA 170000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "CAB018594: AB_668044, HPA008572: AB_2668094" "unprognostic (3.24e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (9.51e-2)" "unprognostic (3.46e-3)" "unprognostic (3.45e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (8.28e-3)" "unprognostic (2.76e-3)" "unprognostic (1.26e-3)" "unprognostic (1.82e-2)" "prognostic unfavorable (5.95e-5)" "unprognostic (7.05e-2)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.30e-1)" "unprognostic (1.28e-2)" "unprognostic (2.35e-2)" 17.5 29.8 5.3 9.9 5.4 0.4 17.3 6.0 6.1 14.8 5.2 25.4 30.4 21.3 11.7 24.1 24.5 17.9 13.2 5.0 10.9 68.9 2.2 65.8 3.0 7.5 6.6 12.8 15.9 17.7 21.1 26.7 11.9 19.5 15.5 4.4 19.4 15.7 9.0 30.8 26.7 15.6 4.2 11.1 24.5 2.1 7.8 5.9 43.5 4.1 6.2 46.7 17.1 4.0 181.8 234.9 1.4 7.5 4.3 17.5 37.3 83.4 177.9 123.1 93.2 5.3 276.2 0.4 507.9 59.5 400.4 126.8 2.2 647.2 73.9 22.9 3.5 0.1 56.8 1.6 105.1 0.3 5.0 21.6 313.5 123.2 540.7 572.8 91.6 9.1 0.1 2.6 236.0 52.9 0.7 0.5 5.5 81.2 141.0 0.4 12.1 13.7 562.0 311.1 9.7 3.9 89.8 12.2 205.0 56.2 21.1 2.4 200.8 541.8 169.4 5.6 329.5 8.1 14.2 5.9 920.8 1.9 570.9 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 5.3 5.4 6.0 6.1 5.0 10.9 7.5 6.6 11.9 4.2 7.8 4.0 8.5 54.5 30.1 3.6 3.4 57.4 63.5 63.5 48.3 18.0 17.1 32.0 5.3 27.1 26.2 77.3 25.0 2.8 1.3 91.2 0.0 111.9 0.5 26.4 3.1 14.7 14.5 0.0 24.3 105.1 3.2 5.3 47.4 20.7 3.8 3.4 8.9 0.3 1.1 3.3 20.0 25.1 16.2 1.2 8.2 0.6 1.8 2.0 17.8 8.4 4.3 3.1 2.1 3.0 0.8 245.6 26.7 4.1 4.5 72.6 69.6 4.4 21.7 16.2 13.1 5.6 23.4 0.5 1.6 17.0 23.2 1.8 3.8 0.9 44.7 104.2 ITGA4 CD49D ENSG00000115232 "Integrin subunit alpha 4" P13612 2 181457202-181538940 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 47.1;lymphoid tissue: 74.1" "Group enriched" "Detected in many" 4 "B-cells: 86.3;dendritic cells: 151.5;Erythroid cells: 169.3;Macrophages: 72.0;monocytes: 73.8;NK-cells: 126.7;Plasma cells: 141.6;T-cells: 129.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 164.0;HEL: 308.1;JURKAT: 142.3;MOLT-4: 373.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in all" 5 "cerebellum: 12.9" HPA074961 Approved "Plasma membrane" "Intracellular and membrane" NA NA 120000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA074961: AB_2732273" "unprognostic (5.31e-2)" "unprognostic (1.54e-1)" "unprognostic (1.99e-2)" "unprognostic (3.94e-2)" "unprognostic (3.76e-1)" "prognostic favorable (8.29e-4)" "unprognostic (1.27e-1)" "unprognostic (1.11e-2)" "unprognostic (1.76e-1)" "unprognostic (2.67e-2)" "unprognostic (1.85e-1)" "unprognostic (1.94e-1)" "prognostic unfavorable (3.08e-5)" "unprognostic (2.26e-2)" "unprognostic (8.64e-3)" "unprognostic (2.49e-1)" "unprognostic (2.57e-2)" 3.3 2.3 1.2 31.5 0.5 47.1 3.8 4.1 1.5 12.7 3.0 8.7 8.7 3.3 1.4 2.3 1.5 9.8 1.5 4.1 1.3 2.7 5.7 12.7 37.2 1.4 1.6 1.4 1.5 0.9 0.4 14.7 2.9 3.5 10.3 8.6 2.9 2.5 0.6 1.2 11.7 5.2 0.9 45.5 10.4 0.8 2.4 74.1 2.0 0.9 26.1 9.5 1.4 1.3 0.3 1.3 4.6 0.1 38.9 55.0 0.0 42.3 46.7 19.5 42.0 0.0 0.0 32.4 0.2 164.0 17.4 23.4 14.0 0.7 22.3 0.0 3.4 308.1 1.1 0.0 4.0 123.4 6.8 39.2 0.0 1.2 0.0 20.5 2.3 142.3 0.1 45.5 12.7 0.0 373.6 117.9 3.7 0.0 0.2 78.1 20.3 5.1 0.0 0.0 8.2 2.6 0.1 0.4 1.4 1.6 0.0 82.9 23.2 6.5 4.1 0.7 8.5 90.9 77.5 18.6 3.7 59.5 90.3 29.5 55.0 137.4 42.0 131.3 32.1 37.3 46.9 52.4 66.0 33.0 26.5 33.1 7.1 32.2 139.6 17.5 13.4 65.2 1.2 0.5 4.1 1.5 4.1 1.3 1.4 1.6 2.9 0.9 2.4 1.3 2.8 0.0 6.7 0.0 86.3 0.3 0.2 1.2 0.0 2.3 1.1 1.4 1.2 2.8 1.8 0.0 6.2 0.1 151.5 0.1 0.0 0.0 0.0 4.4 6.5 1.4 0.0 169.3 9.4 0.0 0.3 6.3 7.1 6.4 18.9 0.3 1.8 0.2 5.9 0.0 0.5 0.1 0.0 24.5 4.4 0.0 0.6 72.0 0.0 7.5 73.8 0.2 126.7 15.6 0.3 0.0 0.4 0.0 141.6 0.3 0.0 0.2 0.8 6.4 0.0 0.7 8.3 0.7 1.2 0.3 0.6 0.4 129.9 0.4 0.2 0.2 ITGA8 ENSG00000077943 "Integrin subunit alpha 8" P53708 10 15513954-15719922 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein, Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 37.4" "Cell type enhanced" "Detected in many" "Excitatory neurons: 82.8;Inhibitory neurons: 56.1;Microglial cells: 34.7;Oligodendrocyte precursor cells: 64.8;Plasma cells: 25.5;Sertoli cells: 52.6;Smooth muscle cells: 57.6" "Cancer enhanced" "Detected in many" "prostate cancer: 6.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 8.4;HMC-1: 19.8;HSkMC: 8.7;U-266/84: 9.7" "Low region specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 14.1" HPA003432 Approved Approved "Plasma membrane" NA NA 200000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003432: AB_1851825" "unprognostic (2.15e-1)" "unprognostic (1.22e-3)" "unprognostic (1.05e-2)" "unprognostic (2.03e-1)" "unprognostic (1.25e-2)" "unprognostic (8.44e-4)" "unprognostic (2.23e-1)" "unprognostic (6.13e-3)" "unprognostic (6.82e-2)" "unprognostic (3.80e-1)" "unprognostic (2.54e-2)" "unprognostic (1.27e-1)" "unprognostic (4.10e-3)" "unprognostic (1.39e-1)" "unprognostic (1.71e-1)" "unprognostic (2.26e-1)" "unprognostic (6.03e-2)" 8.6 10.5 1.6 2.1 2.1 0.1 2.7 1.9 5.0 23.8 8.0 6.1 6.7 9.7 5.5 9.8 8.8 6.7 7.7 7.0 0.9 10.0 0.7 20.8 3.2 1.5 2.8 5.7 0.8 4.7 3.2 0.2 1.1 37.4 6.1 1.6 1.8 30.8 2.9 3.3 6.8 9.1 1.5 19.9 19.3 0.6 1.5 1.0 5.6 6.9 4.4 15.7 9.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.7 1.6 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.0 0.0 0.0 0.0 8.4 2.5 0.0 0.0 0.0 0.0 19.8 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 9.7 0.0 0.0 0.1 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 2.1 1.9 5.0 7.0 0.9 1.5 2.8 1.1 1.5 1.5 2.2 1.2 0.0 1.3 0.7 2.4 1.0 1.9 0.0 0.6 6.3 0.1 0.3 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 4.0 11.4 0.0 0.0 82.8 0.0 0.0 10.1 0.0 0.2 0.0 0.0 4.2 0.0 0.1 0.0 56.1 0.0 0.0 0.0 1.8 0.1 0.9 0.5 1.8 34.7 0.0 13.6 0.0 64.8 4.0 0.0 0.0 0.0 25.5 1.5 0.0 0.0 0.0 0.3 52.6 11.3 57.6 0.0 0.2 0.4 1.1 0.0 1.2 0.1 0.1 1.4 ITSN1 "ITSN, MGC134948, MGC134949, SH3D1A, SH3P17" ENSG00000205726 "Intersectin 1" Q15811 21 33642400-33899861 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Exocytosis, Host-virus interaction, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 217.4;Inhibitory neurons: 151.9;Rod photoreceptor cells: 146.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "eosinophil: 5.5;non-classical monocyte: 5.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018007 Approved Supported "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA018007: AB_1851836" "unprognostic (2.12e-1)" "unprognostic (1.51e-1)" "unprognostic (1.62e-1)" "unprognostic (1.21e-1)" "unprognostic (3.91e-1)" "unprognostic (1.81e-1)" "unprognostic (1.10e-1)" "unprognostic (3.94e-2)" "unprognostic (7.33e-3)" "unprognostic (1.31e-2)" "unprognostic (3.23e-1)" "unprognostic (3.25e-2)" "unprognostic (1.16e-2)" "unprognostic (6.78e-3)" "unprognostic (2.37e-1)" "unprognostic (6.02e-2)" "unprognostic (5.64e-2)" 55.5 15.5 18.0 9.9 18.4 6.8 27.9 16.4 26.2 19.8 22.8 14.7 8.9 20.3 12.0 11.4 16.7 19.8 20.9 18.3 14.0 10.9 26.4 11.5 6.8 14.5 13.6 19.6 5.0 7.0 6.7 24.4 14.9 14.5 11.0 28.5 7.9 22.3 22.0 11.9 9.7 18.4 8.8 15.4 11.1 12.3 17.0 5.0 10.3 22.0 3.9 15.4 13.4 14.1 36.3 14.9 70.4 23.4 32.3 30.8 115.3 35.8 34.4 20.6 19.8 56.7 27.0 8.5 28.3 43.1 42.7 13.7 42.2 24.9 22.0 3.5 18.6 10.3 30.9 26.7 24.4 7.4 9.9 30.5 22.0 38.6 21.2 23.5 55.3 9.8 13.7 5.8 33.4 8.2 10.3 9.8 104.5 12.6 11.3 13.2 33.7 17.6 30.9 14.7 13.2 14.4 51.4 10.6 12.6 44.6 13.0 7.2 50.2 22.9 30.9 18.1 12.5 7.0 20.8 7.9 20.8 22.9 26.0 0.0 4.2 5.5 0.3 3.2 0.3 0.0 0.5 0.1 1.3 0.0 0.2 0.1 0.2 0.1 5.1 0.3 0.0 0.8 18.0 18.4 16.4 26.2 18.3 14.0 14.5 13.6 14.9 8.8 17.0 14.1 19.8 25.6 18.6 217.4 1.8 18.1 22.6 10.8 36.5 73.1 12.2 8.1 81.8 18.6 14.5 11.0 91.8 20.8 1.1 22.4 0.0 19.9 10.2 13.3 67.7 21.3 9.1 47.4 110.9 12.5 28.0 31.9 19.4 21.0 2.5 30.7 28.2 54.2 55.6 65.6 151.9 7.2 20.3 30.0 10.9 8.6 24.8 27.3 10.6 74.0 10.8 46.9 0.0 80.4 46.4 37.1 10.3 71.5 3.1 18.3 16.8 16.6 18.8 146.2 13.1 20.1 39.7 32.4 47.7 8.9 11.8 15.6 2.7 21.4 10.5 27.2 IYD "C6orf71, DEHAL1, dJ422F24.1" ENSG00000009765 "Iodotyrosine deiodinase" Q6PHW0 6 150368892-150405969 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Congenital hypothyroidism, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "thyroid gland: 472.7" "Cell type enhanced" "Detected in some" "Distal enterocytes: 23.7;Hepatocytes: 25.1;Intestinal goblet cells: 21.8;Paneth cells: 22.5;Proximal enterocytes: 89.1;Proximal tubular cells: 35.4" "Cancer enriched" "Detected in many" 20 "thyroid cancer: 80.7" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CACO-2: 1.3;OE19: 3.0;SK-BR-3: 3.2" "Group enriched" "Detected in some" 13 "hippocampal formation: 7.4;thalamus: 2.4" "Low region specificity" "Detected in all" HPA059627 Enhanced Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 1: Thyroid gland - Transcription" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA059627: AB_2684086" "unprognostic (3.73e-4)" "unprognostic (2.93e-2)" "unprognostic (5.97e-2)" "unprognostic (1.95e-2)" "unprognostic (1.55e-1)" "unprognostic (2.98e-2)" "prognostic favorable (6.22e-4)" "unprognostic (1.11e-1)" "unprognostic (3.80e-2)" "unprognostic (1.17e-1)" "unprognostic (7.41e-2)" "unprognostic (1.02e-1)" "unprognostic (3.07e-9)" "unprognostic (9.79e-3)" "unprognostic (2.04e-1)" "unprognostic (2.03e-2)" "unprognostic (2.18e-2)" 0.1 0.0 0.4 0.6 0.3 0.3 0.5 0.6 0.6 0.1 0.2 6.4 18.1 0.2 0.6 0.0 0.0 8.9 0.5 0.3 0.1 26.6 33.6 0.7 0.5 0.5 0.4 0.0 0.4 0.0 0.0 0.0 0.6 0.2 6.5 0.2 0.1 0.0 0.0 0.2 19.6 0.2 0.0 0.1 2.0 0.2 0.5 0.0 472.7 0.0 0.2 0.1 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 1.3 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 3.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 3.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.0 1.6 0.5 0.3 0.2 0.4 0.2 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.9 0.7 0.2 0.3 0.2 1.3 0.4 0.3 0.6 0.6 0.3 0.1 0.5 0.4 0.6 0.0 0.5 0.5 0.7 3.2 7.8 0.0 0.0 0.1 0.6 0.2 0.0 0.1 0.3 0.4 0.8 14.3 8.9 0.0 0.0 0.1 0.0 23.7 1.9 0.3 0.0 0.9 0.3 0.4 3.6 2.7 0.1 0.2 0.0 0.7 0.0 2.2 1.3 0.1 1.1 25.1 0.1 0.0 0.1 21.8 0.0 0.0 1.2 0.1 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.4 22.5 0.0 0.0 1.0 89.1 35.4 3.6 1.3 0.0 1.7 0.3 0.1 0.1 0.0 0.4 0.3 0.9 0.4 11.5 0.7 KANK1 "ANKRD15, KANK, KIAA0172" ENSG00000107104 "KN motif and ankyrin repeat domains 1" Q14678 9 470291-746106 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 355.5;Late spermatids: 228.7;Oligodendrocyte precursor cells: 322.7;Oligodendrocytes: 191.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.0" "Group enriched" "Detected in many" 15 "B-cells: 1.1;dendritic cells: 4.0;T-cells: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 96.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005539, HPA056090" Approved Supported "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 15: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA005539: AB_1078164, HPA056090: AB_2683034" "unprognostic (6.59e-2)" "unprognostic (3.33e-2)" "unprognostic (1.06e-3)" "unprognostic (1.30e-1)" "unprognostic (2.69e-1)" "unprognostic (7.53e-2)" "unprognostic (3.33e-1)" "unprognostic (1.23e-2)" "unprognostic (4.91e-2)" "unprognostic (3.05e-2)" "unprognostic (2.84e-2)" "unprognostic (1.24e-1)" "unprognostic (3.07e-2)" "unprognostic (2.72e-1)" "unprognostic (3.06e-2)" "unprognostic (1.82e-1)" "unprognostic (1.61e-1)" 42.6 9.6 49.0 9.5 52.7 1.5 31.2 42.3 47.5 40.9 61.8 49.2 12.1 62.2 13.0 64.6 31.7 15.2 88.2 45.1 44.9 31.6 101.9 13.6 7.6 51.6 44.9 22.1 28.3 9.4 27.9 25.8 48.3 42.5 14.9 11.0 29.9 31.8 66.4 51.8 23.6 37.4 47.6 6.9 25.9 15.4 48.4 9.4 30.8 39.9 11.8 70.1 52.3 48.9 5.9 12.2 4.0 72.0 57.8 21.9 19.9 37.1 25.8 3.1 3.7 30.2 2.5 46.2 8.9 46.0 7.0 12.3 15.7 30.4 5.3 22.7 8.3 0.1 17.0 96.0 8.1 11.2 0.0 12.6 41.6 3.2 35.6 13.2 31.2 1.6 2.4 56.4 23.1 14.4 4.5 46.9 5.3 8.9 9.0 1.7 7.9 8.6 24.5 36.1 1.8 0.0 3.6 10.9 50.9 33.3 7.1 8.7 46.1 8.4 3.2 10.8 17.1 9.8 61.9 0.2 5.6 21.1 15.8 0.0 0.1 0.0 0.1 0.1 0.0 0.8 1.3 0.4 0.4 1.1 2.4 0.8 0.0 0.1 0.0 4.0 1.7 0.5 49.0 52.7 42.3 47.5 45.1 44.9 51.6 44.9 48.3 47.6 48.4 48.9 18.3 12.8 34.2 355.5 4.9 23.1 102.1 11.4 37.0 22.2 16.8 18.0 94.1 24.3 8.1 18.4 41.7 89.2 15.7 8.3 7.9 11.6 102.3 14.2 15.4 21.9 18.0 9.1 12.1 7.9 6.8 21.8 7.7 13.1 1.3 38.5 23.6 70.0 13.3 0.0 29.0 12.8 4.1 6.9 6.5 228.7 32.3 3.3 23.2 60.9 1.2 6.5 0.0 322.7 191.4 9.6 7.5 20.7 10.7 50.5 17.6 13.6 7.0 20.2 26.3 129.9 24.0 28.4 25.6 36.2 25.7 66.2 4.7 6.9 26.0 63.6 KANK3 "ANKRD47, FLJ46061" ENSG00000186994 "KN motif and ankyrin repeat domains 3" Q6NY19 19 8322584-8343262 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 5 "Adipocytes: 196.2;Endothelial cells: 83.8;Hepatic stellate cells: 55.3" "Cancer enhanced" "Detected in all" "testis cancer: 7.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 4 "NK-cells: 1.2;T-cells: 1.0" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 8.1;TIME: 14.8;U-266/70: 5.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "olfactory bulb: 16.2" HPA051153 Approved Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA051153: AB_2681365" "unprognostic (1.56e-1)" "unprognostic (1.63e-4)" "unprognostic (1.54e-2)" "unprognostic (8.95e-3)" "unprognostic (1.07e-1)" "unprognostic (2.84e-3)" "unprognostic (1.82e-3)" "unprognostic (3.26e-2)" "unprognostic (1.19e-1)" "unprognostic (1.39e-2)" "unprognostic (1.34e-2)" "unprognostic (4.77e-1)" "prognostic favorable (1.69e-5)" "unprognostic (5.03e-2)" "unprognostic (1.67e-1)" "unprognostic (2.86e-1)" "unprognostic (3.24e-1)" 25.6 7.6 12.0 2.3 9.7 0.6 26.1 9.6 12.2 8.2 5.8 6.2 2.9 10.2 0.7 5.1 11.2 2.5 32.9 8.7 8.9 22.2 4.2 33.4 2.8 12.5 11.5 3.6 3.9 1.5 6.9 14.6 11.5 7.6 0.5 0.3 4.1 1.8 13.7 6.7 7.3 2.4 9.7 35.5 6.2 2.4 13.2 0.7 15.5 6.0 0.8 7.9 6.8 8.9 0.1 0.6 0.2 0.5 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.7 0.2 0.0 2.3 0.0 0.0 0.1 0.5 2.6 0.0 0.7 1.4 0.3 0.3 0.4 0.1 0.2 1.3 0.0 0.8 0.0 0.0 0.0 8.1 0.6 0.0 0.3 0.0 0.4 0.0 0.4 0.5 0.5 0.2 1.4 0.0 0.7 0.1 0.1 0.0 0.1 0.0 0.7 0.1 0.0 0.5 0.0 14.8 0.0 1.3 0.3 0.1 5.9 0.2 0.3 0.1 0.1 0.2 0.2 0.1 0.0 1.0 0.0 0.5 0.1 0.5 0.1 0.0 0.1 0.2 0.4 0.2 1.2 0.0 0.0 0.4 0.2 12.0 9.7 9.6 12.2 8.7 8.9 12.5 11.5 11.5 9.7 13.2 8.9 196.2 6.4 3.2 2.0 0.3 2.5 0.4 0.6 0.6 0.3 1.5 2.5 2.2 0.0 0.8 0.0 4.2 0.4 3.8 0.1 5.9 0.1 6.6 0.5 0.7 83.8 0.0 2.7 0.6 1.8 0.3 6.4 1.5 0.8 0.0 0.2 55.3 1.0 0.5 0.0 0.9 0.0 0.0 1.3 2.1 8.1 0.6 0.9 5.4 18.7 0.0 0.4 12.3 0.5 1.6 0.6 0.1 0.4 0.4 1.0 0.0 0.4 0.7 0.7 19.7 8.3 12.9 6.5 3.6 1.1 1.3 0.3 2.8 4.0 0.1 0.8 KCNE3 "HOKPP, MiRP2" ENSG00000175538 "Potassium voltage-gated channel subfamily E regulatory subunit 3" Q9Y6H6 11 74454841-74467729 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Brugada syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 70.5;stomach 1: 56.2" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 41.8;granulocytes: 33.7;Hofbauer cells: 40.6;Kupffer cells: 104.0;Macrophages: 37.8;monocytes: 59.0;Undifferentiated cells: 44.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 48 "basophil: 51.4;classical monocyte: 38.5;eosinophil: 23.4;intermediate monocyte: 41.8;myeloid DC: 18.3;neutrophil: 53.1;non-classical monocyte: 36.6" "Group enriched" "Detected in many" 115 "dendritic cells: 18.3;granulocytes: 53.1;monocytes: 41.8" "Cell line enhanced" "Detected in some" "HEL: 70.3;NB-4: 44.7;OE19: 155.3;THP-1: 32.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA014849 Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "HPA014849: AB_1852112" "unprognostic (1.61e-2)" "unprognostic (2.94e-1)" "unprognostic (1.11e-1)" "unprognostic (8.69e-2)" "unprognostic (3.58e-1)" "unprognostic (5.13e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (4.67e-3)" "unprognostic (4.89e-4)" "unprognostic (4.12e-3)" "unprognostic (2.56e-2)" "unprognostic (2.97e-2)" "unprognostic (1.45e-3)" "unprognostic (7.86e-2)" "unprognostic (1.33e-2)" "unprognostic (1.73e-1)" "unprognostic (2.00e-1)" 7.3 2.8 2.8 20.7 2.9 8.2 5.2 2.5 3.6 9.9 7.0 34.9 70.5 8.8 1.9 4.6 9.4 24.6 5.0 3.0 3.0 20.1 5.0 13.8 5.0 3.8 3.6 14.0 10.8 3.6 3.1 12.7 3.6 8.0 47.3 8.1 15.4 3.4 1.3 1.3 40.0 11.1 3.3 12.6 56.2 1.8 4.1 1.9 33.5 3.0 3.2 6.2 4.5 4.9 0.1 0.1 0.1 0.2 8.1 2.1 7.1 0.1 0.0 1.0 0.8 23.0 2.0 0.3 21.3 0.1 0.1 0.3 1.8 0.0 0.7 0.0 0.2 70.3 0.4 4.7 2.9 0.6 12.0 7.1 0.0 0.6 0.0 0.3 0.3 0.1 1.9 0.3 0.8 0.1 0.1 44.7 0.9 155.3 0.1 7.6 0.3 0.5 1.7 0.0 0.0 0.4 0.1 0.0 0.0 5.4 0.1 32.7 0.1 0.1 0.2 0.2 0.1 0.3 0.3 0.4 0.1 12.9 0.1 51.4 38.5 23.4 0.1 41.8 0.2 0.2 0.1 0.1 18.3 0.3 0.1 0.1 53.1 0.2 36.6 0.7 0.0 13.2 2.8 2.9 2.5 3.6 3.0 3.0 3.8 3.6 3.6 3.3 4.1 4.9 4.4 0.0 6.8 0.3 0.7 0.3 0.6 1.1 3.4 0.2 0.2 0.3 0.7 8.6 5.6 1.8 0.0 0.4 0.0 8.6 3.9 0.5 0.1 3.1 3.4 8.9 2.4 2.1 0.2 7.3 7.4 4.5 41.8 5.0 33.7 0.2 5.7 2.0 40.6 0.0 0.3 27.9 4.1 104.0 2.9 0.3 3.7 37.8 0.0 8.4 59.0 22.7 1.0 0.0 0.0 3.3 8.9 2.6 0.2 0.4 8.6 23.4 4.6 1.2 0.0 4.7 0.7 0.0 0.4 2.7 0.1 2.1 1.0 8.8 44.3 0.6 KCNH8 "elk3, Kv12.1" ENSG00000183960 "Potassium voltage-gated channel subfamily H member 8" Q96L42 3 19148510-19535642 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 16.0;pituitary gland: 10.7" "Group enriched" "Detected in some" 63 "Oligodendrocyte precursor cells: 331.7;Oligodendrocytes: 989.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.4" "Lineage enriched" "Detected in single" 4 "B-cells: 1.4" "Cell line enhanced" "Detected in some" "HAP1: 1.0;OE19: 1.9;SH-SY5Y: 4.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA016586, HPA077537, HPA077773" Approved Supported "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA016586: AB_1852127, HPA077537: , HPA077773: " "unprognostic (6.68e-3)" "unprognostic (1.68e-1)" "unprognostic (2.99e-2)" "unprognostic (8.56e-6)" "unprognostic (1.04e-1)" "unprognostic (1.10e-1)" "unprognostic (1.88e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (1.69e-1)" "unprognostic (5.04e-3)" "unprognostic (2.90e-2)" "unprognostic (1.63e-1)" "unprognostic (1.17e-1)" "unprognostic (3.89e-2)" "unprognostic (8.71e-5)" "unprognostic (1.72e-1)" 0.0 1.8 7.3 0.3 11.9 0.2 0.5 6.5 16.0 0.3 2.8 0.6 0.4 0.1 0.1 0.1 0.2 0.4 0.2 6.4 8.8 0.1 0.1 0.0 0.8 8.4 8.8 0.0 1.5 0.1 10.7 0.0 8.2 0.7 0.5 3.4 1.1 0.2 0.0 0.4 1.1 0.1 5.8 1.1 1.4 1.7 9.7 0.4 0.2 0.0 0.7 0.1 0.3 15.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.5 4.3 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 7.3 11.9 6.5 16.0 6.4 8.8 8.4 8.8 8.2 5.8 9.7 15.4 0.0 0.0 0.0 2.0 9.7 0.5 1.6 0.0 0.0 4.2 1.1 2.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.9 3.2 0.1 0.1 0.1 3.6 0.0 9.3 0.6 0.0 0.1 2.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 10.4 1.5 0.0 0.0 0.0 1.9 0.0 0.1 3.6 1.0 0.0 3.4 0.0 331.7 989.4 0.5 0.2 0.0 0.1 1.5 0.0 0.0 0.0 1.0 0.0 0.2 0.5 1.2 3.4 0.0 0.0 0.1 0.3 0.1 0.6 0.4 KCNK7 K2p7.1 ENSG00000173338 "Potassium two pore domain channel subfamily K member 7" Q9Y2U2 11 65592836-65595996 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 90.0" "Cell type enriched" "Detected in some" 5 "Suprabasal keratinocytes: 103.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.4" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 15 "basophil: 2.1;naive B-cell: 2.2;neutrophil: 1.5" "Group enriched" "Detected in many" 16 "B-cells: 2.2;granulocytes: 2.1" "Cell line enhanced" "Detected in some" "SCLC-21H: 6.8" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA077577 Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA077577: AB_2686845" "unprognostic (1.12e-2)" "unprognostic (1.21e-1)" "unprognostic (6.08e-2)" "unprognostic (5.71e-2)" "unprognostic (8.59e-2)" "unprognostic (1.34e-1)" "unprognostic (1.68e-3)" "unprognostic (8.53e-2)" "unprognostic (1.69e-1)" "unprognostic (2.87e-1)" "unprognostic (6.90e-2)" "unprognostic (4.88e-2)" "unprognostic (1.49e-2)" "unprognostic (2.65e-1)" "unprognostic (3.57e-1)" "unprognostic (1.16e-1)" "unprognostic (8.11e-2)" 2.0 0.7 2.7 0.2 2.9 5.4 2.9 3.4 5.7 4.6 1.7 2.1 0.4 1.4 0.1 18.0 2.3 0.3 1.6 2.7 2.4 0.7 0.9 1.7 0.3 2.8 2.8 1.8 0.4 0.0 1.3 0.4 3.0 1.4 0.0 0.7 2.5 0.3 2.6 90.0 1.2 0.2 2.7 2.0 1.2 1.1 2.7 0.4 0.6 0.5 1.0 1.7 9.5 3.4 0.3 1.6 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.3 0.1 0.1 1.0 0.4 0.4 0.1 0.2 2.2 0.0 0.0 0.0 0.5 1.1 0.5 0.9 0.6 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.2 0.0 0.8 0.6 1.3 0.4 1.0 0.5 0.4 0.6 0.6 0.6 0.9 0.0 0.2 0.6 0.1 6.8 1.5 0.3 0.4 0.7 0.0 0.4 1.1 0.0 0.3 1.1 1.0 0.1 0.9 0.7 0.2 0.5 0.6 0.6 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.2 0.0 0.0 1.5 0.1 0.1 0.0 0.0 0.0 2.7 2.9 3.4 5.7 2.7 2.4 2.8 2.8 3.0 2.7 2.7 3.4 1.1 0.0 0.5 0.3 0.8 19.1 0.4 0.7 0.6 2.1 0.7 1.8 0.2 0.0 0.7 0.0 0.0 0.1 1.6 1.0 0.0 0.1 0.7 0.7 0.3 1.2 1.2 0.0 0.9 0.0 0.1 0.4 0.0 1.7 0.0 0.2 0.7 0.3 0.5 0.0 0.9 0.4 0.0 1.3 4.0 1.8 0.6 0.7 3.6 0.0 0.4 0.1 0.0 1.0 1.8 0.1 4.8 0.0 0.0 0.3 0.3 0.1 1.1 1.1 6.6 0.4 0.8 0.1 1.3 16.3 103.7 0.0 0.6 0.1 0.8 1.3 KCNK9 "K2p9.1, TASK-3, TASK3" ENSG00000169427 "Potassium two pore domain channel subfamily K member 9" Q9NPC2 8 139600838-139704109 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel" "Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 7.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 16.0;Inhibitory neurons: 8.0;Late spermatids: 9.7" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 4 "cerebellum: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA075842 Approved "Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA075842: " "unprognostic (1.84e-2)" "unprognostic (2.57e-1)" "unprognostic (1.58e-1)" "unprognostic (8.96e-8)" "unprognostic (1.91e-1)" "unprognostic (8.17e-3)" "unprognostic (2.19e-3)" "unprognostic (1.65e-1)" "unprognostic (3.87e-1)" "unprognostic (1.69e-1)" "unprognostic (1.00e-2)" "unprognostic (3.21e-1)" "unprognostic (5.12e-6)" "unprognostic (2.94e-2)" "unprognostic (1.64e-1)" "unprognostic (9.99e-3)" "unprognostic (1.76e-1)" 0.0 1.6 0.0 0.1 0.0 0.0 0.0 7.8 1.9 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.7 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 1.9 0.2 0.1 0.8 0.3 0.9 0.0 0.4 0.3 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.4 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.3 2.1 0.0 0.0 0.0 0.0 0.0 16.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.8 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 KCNU1 "KCa5.1, Kcnma3, KCNMC1, Slo3" ENSG00000215262 "Potassium calcium-activated channel subfamily U member 1" A8MYU2 8 36784324-36936125 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 13 "testis: 7.5" "Group enriched" "Detected in some" 15 "Early spermatids: 61.1;Late spermatids: 24.3" "Cancer enhanced" "Detected in single" "liver cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "HDLM-2: 7.9" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA063317 Uncertain "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA063317: " "unprognostic (2.42e-3)" "unprognostic (4.26e-2)" "unprognostic (2.07e-1)" "unprognostic (4.76e-3)" "unprognostic (7.57e-2)" "unprognostic (1.12e-1)" "unprognostic (1.11e-1)" "unprognostic (2.71e-1)" "unprognostic (1.98e-1)" "unprognostic (7.73e-2)" "unprognostic (1.24e-2)" 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 7.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.3 0.5 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 61.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 24.3 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 KIT "C-Kit, CD117, PBT, SCFR" ENSG00000157404 "KIT proto-oncogene, receptor tyrosine kinase" P10721 4 54657918-54740715 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 114.9" "Cell type enhanced" "Detected in many" "Breast glandular cells: 83.1;granulocytes: 529.3;Inhibitory neurons: 111.2;Ionocytes: 101.7;Melanocytes: 211.7" "Cancer enhanced" "Detected in many" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 20.3;eosinophil: 12.8;NK-cell: 13.1" "Group enriched" "Detected in many" 7 "granulocytes: 20.3;NK-cells: 13.1" "Group enriched" "Detected in many" 13 "HEL: 247.2;HMC-1: 496.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003288, HPA004471, CAB068253, CAB072867, HPA073252" Enhanced Supported Supported "Plasma membrane" NA NA 49000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 5: Breast - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 60: Granulocytes - Receptor signaling" "Plasma membrane" "CAB003288: AB_2335702, CAB068253: AB_2665717, CAB072867: AB_2665718, HPA004471: AB_1078431, HPA073252: AB_2686589" "unprognostic (1.55e-2)" "unprognostic (1.91e-1)" "unprognostic (4.04e-2)" "unprognostic (8.19e-2)" "unprognostic (3.96e-2)" "unprognostic (2.18e-2)" "unprognostic (2.33e-2)" "unprognostic (1.97e-2)" "unprognostic (3.60e-2)" "unprognostic (1.64e-1)" "unprognostic (2.20e-1)" "unprognostic (1.92e-2)" "prognostic favorable (5.63e-4)" "unprognostic (1.34e-3)" "unprognostic (1.87e-1)" "unprognostic (1.29e-2)" "unprognostic (2.30e-1)" 6.6 1.8 8.2 5.3 6.3 6.4 114.9 21.4 6.5 17.6 5.1 13.5 9.2 9.6 5.9 13.0 2.9 20.3 3.4 23.9 5.1 12.4 0.8 21.8 3.4 6.8 12.3 45.0 2.6 1.7 1.9 10.0 8.8 5.6 16.0 3.2 21.4 8.7 1.1 24.5 13.4 10.1 5.9 5.0 17.4 6.2 16.7 3.1 47.1 6.9 6.2 14.5 4.9 5.1 0.0 0.0 3.9 0.0 0.7 0.3 0.0 3.3 4.6 12.6 15.8 0.0 0.0 0.0 0.0 7.3 0.6 0.3 2.6 0.0 10.8 0.0 5.9 247.2 0.0 0.0 0.0 0.0 496.2 0.0 0.0 0.0 0.0 0.0 28.4 4.3 3.5 0.5 0.0 0.0 1.4 2.5 6.9 0.0 0.0 0.8 0.0 0.0 0.0 24.2 6.0 2.1 0.0 0.0 0.0 14.1 0.0 2.6 0.3 0.5 0.0 4.9 0.1 0.4 0.0 0.0 0.5 0.9 0.6 20.3 0.0 12.8 0.1 0.0 2.3 0.0 0.4 0.9 2.3 0.0 0.0 0.0 1.0 13.1 1.4 0.1 0.0 0.2 8.2 6.3 21.4 6.5 23.9 5.1 6.8 12.3 8.8 5.9 16.7 5.1 7.3 6.4 21.9 9.8 1.0 14.3 0.9 0.4 2.2 4.5 83.1 59.2 0.7 4.3 3.6 3.7 0.0 0.1 5.2 0.4 3.9 1.0 0.0 0.2 0.7 9.2 5.4 15.5 0.9 0.0 0.1 2.8 8.6 0.7 529.3 0.5 1.8 0.0 0.3 0.0 111.2 0.5 101.7 0.3 4.2 0.4 1.2 1.6 211.7 14.0 0.2 2.4 0.0 16.1 3.7 0.0 0.1 0.0 3.2 0.5 0.0 0.8 0.1 0.2 0.0 0.7 0.8 0.1 12.3 2.2 3.8 0.3 8.8 63.7 0.6 0.3 KLHDC7B MGC16635 ENSG00000130487 "Kelch domain containing 7B" Q96G42 22 50545899-50551023 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 5.2;parathyroid gland: 13.7" "Cell type enhanced" "Detected in some" "B-cells: 5.2;Collecting duct cells: 5.5;granulocytes: 5.7;Kupffer cells: 5.2;monocytes: 21.1;NK-cells: 10.3;T-cells: 5.7" "Group enriched" "Detected in many" 4 "cervical cancer: 42.3;head and neck cancer: 11.4;urothelial cancer: 40.7" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in some" 4 "HMC-1: 97.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA000518, HPA076540" Uncertain Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA000518: AB_1079213, HPA076540: " "prognostic favorable (1.30e-4)" "unprognostic (3.18e-2)" "unprognostic (2.74e-2)" "unprognostic (2.21e-1)" "unprognostic (3.96e-2)" "unprognostic (6.04e-3)" "unprognostic (3.91e-1)" "unprognostic (1.07e-1)" "unprognostic (1.07e-2)" "unprognostic (7.13e-2)" "unprognostic (3.33e-3)" "unprognostic (2.48e-1)" "unprognostic (2.09e-3)" "unprognostic (2.89e-1)" "unprognostic (4.69e-2)" "unprognostic (3.49e-1)" "unprognostic (1.02e-1)" 0.2 0.2 0.2 2.1 0.1 1.0 0.3 0.1 0.2 0.5 0.1 0.3 0.4 0.2 0.3 0.4 0.1 0.3 0.0 0.1 0.2 3.7 0.4 0.7 2.3 0.5 0.2 0.0 0.1 13.7 1.0 0.1 0.3 0.4 0.1 0.0 1.3 0.2 0.0 0.3 1.1 0.1 0.2 2.7 0.5 0.2 0.4 5.2 2.0 0.0 1.3 1.5 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.8 0.0 0.8 0.1 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.0 0.2 97.7 0.1 1.2 0.0 0.2 0.1 0.0 0.0 0.0 11.6 0.0 0.0 0.0 8.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.7 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.3 0.0 0.1 1.1 1.1 0.1 2.0 1.9 1.4 1.9 2.1 2.6 0.9 1.3 2.3 2.0 0.2 0.7 1.4 0.3 2.0 1.5 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.2 0.3 0.2 0.4 0.2 0.0 0.0 0.6 0.0 5.2 0.1 0.0 1.6 0.0 0.0 3.0 1.4 0.5 0.0 1.6 5.5 0.0 0.0 2.5 0.1 0.0 0.8 0.0 0.2 0.0 0.1 0.0 0.4 0.0 0.7 0.1 0.2 0.5 0.3 5.7 0.0 0.0 0.1 1.6 0.0 0.0 0.0 0.0 5.2 1.2 0.0 0.0 2.7 0.0 0.0 21.1 0.0 10.3 0.0 0.0 1.3 0.0 0.0 2.8 0.1 0.0 0.3 1.6 0.0 0.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 5.7 0.0 0.0 0.2 KLRC1 "CD159a, NKG2, NKG2-A, NKG2-B" ENSG00000134545 "Killer cell lectin like receptor C1" P26715 12 10442264-10454685 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 6.7" "Group enriched" "Detected in some" 8 "dendritic cells: 104.2;NK-cells: 254.3;T-cells: 100.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 7 "gdT-cell: 229.2;NK-cell: 367.6" "Group enriched" "Detected in many" 46 "NK-cells: 367.6;T-cells: 229.2" "Cell line enhanced" "Detected in some" "HeLa: 5.6;Karpas-707: 1.9" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (8.17e-3)" "unprognostic (2.13e-2)" "unprognostic (1.48e-2)" "unprognostic (4.58e-7)" "unprognostic (3.57e-1)" "unprognostic (1.17e-2)" "unprognostic (1.05e-1)" "unprognostic (3.68e-2)" "unprognostic (3.73e-4)" "unprognostic (4.13e-2)" "unprognostic (6.49e-2)" "unprognostic (2.54e-1)" "unprognostic (1.18e-4)" "unprognostic (1.88e-1)" "unprognostic (3.23e-1)" "unprognostic (2.45e-1)" "unprognostic (1.92e-3)" 0.7 0.5 0.8 2.2 0.8 5.3 2.0 0.6 1.4 0.7 0.4 1.8 1.4 3.1 1.5 1.4 0.9 2.0 0.7 1.0 1.6 0.3 1.8 3.3 3.1 1.4 1.4 0.7 0.8 0.3 0.3 2.2 1.0 0.7 2.0 1.2 1.2 0.4 0.4 1.0 2.6 0.9 1.2 6.7 4.3 0.9 1.8 1.1 0.7 0.0 2.5 1.0 0.6 2.0 0.2 0.8 0.0 0.0 0.2 0.2 0.4 0.0 0.0 0.4 0.8 0.0 0.6 0.1 0.0 0.2 1.6 0.1 0.3 1.4 0.5 0.4 0.2 1.0 5.6 0.0 0.0 0.3 0.1 0.5 0.0 0.1 0.0 0.0 0.4 0.3 0.6 1.9 0.4 0.0 0.1 1.4 0.0 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.2 0.0 0.4 0.0 0.1 1.7 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.0 0.0 0.3 1.0 0.4 0.0 1.9 0.3 0.2 229.2 0.3 29.1 0.6 0.1 40.1 0.3 0.2 0.3 33.2 6.4 367.6 0.6 0.4 0.1 28.6 0.8 0.8 0.6 1.4 1.0 1.6 1.4 1.4 1.0 1.2 1.8 2.0 1.2 0.0 0.6 0.0 1.3 0.1 0.3 0.0 0.0 0.0 0.9 1.3 0.5 1.5 0.0 0.0 0.0 0.1 104.2 0.8 0.0 0.1 1.3 0.3 0.4 0.4 1.8 11.2 0.2 0.0 0.0 0.6 3.1 0.4 0.0 0.0 3.9 0.9 0.1 1.7 0.1 2.8 0.0 4.0 0.4 0.4 0.6 2.0 5.4 0.0 1.4 0.0 254.3 1.0 0.0 0.0 1.2 1.2 17.6 0.1 0.6 0.6 0.0 2.0 0.0 0.1 0.8 1.1 0.6 0.5 0.1 0.1 100.2 0.0 0.5 0.4 KLRC2 "CD159c, NKG2-C" ENSG00000205809 "Killer cell lectin like receptor C2" P26717 12 10426854-10442300 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.4;lymphoid tissue: 5.8" "Group enriched" "Detected in some" 6 "dendritic cells: 111.5;Oligodendrocyte precursor cells: 32.6;T-cells: 49.9" "Cancer enriched" "Detected in single" 8 "glioma: 3.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "gdT-cell: 24.6;NK-cell: 84.5" "Group enriched" "Detected in many" 103 "NK-cells: 84.5;T-cells: 24.6" "Cell line enhanced" "Detected in some" "GAMG: 19.1;HEL: 5.8;HeLa: 17.5;HSkMC: 4.1" HPA058052 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 20: HeLa - Mitochondria" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA058052: AB_2683589" "unprognostic (9.05e-4)" "unprognostic (2.54e-2)" "unprognostic (3.77e-2)" "unprognostic (2.51e-3)" "unprognostic (2.83e-1)" "unprognostic (9.49e-4)" "unprognostic (1.27e-1)" "unprognostic (8.74e-2)" "unprognostic (2.88e-1)" "unprognostic (4.00e-3)" "unprognostic (2.88e-2)" "unprognostic (9.16e-3)" "unprognostic (1.55e-9)" "unprognostic (8.10e-2)" "unprognostic (2.34e-1)" "unprognostic (8.93e-2)" "unprognostic (5.31e-3)" 0.4 0.1 3.9 0.4 3.8 2.2 0.8 3.6 9.4 0.3 2.8 1.3 0.7 0.9 0.0 0.5 0.5 1.1 0.1 3.7 4.1 0.1 0.8 1.0 1.1 4.2 4.2 1.0 0.2 0.0 0.1 0.4 4.1 0.3 0.8 0.3 0.3 0.2 0.0 0.1 1.1 0.0 4.2 5.8 2.3 0.4 3.9 0.3 0.3 0.0 1.3 0.4 0.3 4.7 0.0 0.9 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 19.1 0.0 0.0 2.2 0.0 0.0 0.0 5.8 17.5 0.3 0.0 0.6 0.0 4.1 0.1 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.0 0.1 1.2 0.1 0.4 0.0 0.0 0.0 0.0 0.6 2.8 0.1 0.1 0.0 0.0 0.0 24.6 0.0 0.6 0.0 0.0 11.0 0.0 0.0 0.1 9.2 0.5 84.5 0.1 0.0 0.0 4.6 3.9 3.8 3.6 9.4 3.7 4.1 4.2 4.2 4.1 4.2 3.9 4.7 0.5 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.8 0.3 1.2 0.0 0.6 0.0 0.0 0.0 111.5 0.2 0.0 0.2 0.0 0.1 0.1 0.1 9.6 0.0 0.1 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 1.2 0.0 0.6 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 9.2 32.6 0.2 0.0 0.0 0.0 4.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 49.9 1.7 0.3 0.2 KLRF1 "CLEC5C, NKp80" ENSG00000150045 "Killer cell lectin like receptor F1" Q9NZS2 12 9827481-9845007 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 12.8;lymphoid tissue: 18.0" "Group enriched" "Detected in many" 7 "dendritic cells: 302.0;NK-cells: 963.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in many" 7 "NK-cell: 664.4" "Lineage enriched" "Detected in all" 7 "NK-cells: 664.4" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.5;HAP1: 1.5;U-937: 4.4" HPA054038 Approved "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA054038: " "unprognostic (2.96e-1)" "unprognostic (8.59e-2)" "unprognostic (3.18e-2)" "unprognostic (2.95e-1)" "unprognostic (3.26e-1)" "unprognostic (1.69e-4)" "unprognostic (6.06e-2)" "unprognostic (3.68e-2)" "unprognostic (9.95e-3)" "unprognostic (3.00e-1)" "unprognostic (2.90e-1)" "unprognostic (4.43e-2)" "unprognostic (6.53e-2)" "unprognostic (4.64e-2)" "unprognostic (1.12e-1)" "unprognostic (2.15e-1)" "unprognostic (8.89e-3)" 1.5 0.1 0.6 1.4 0.6 12.8 0.8 0.6 1.4 0.7 0.6 0.7 0.3 0.9 3.8 0.6 1.5 1.4 0.6 0.6 0.6 1.2 4.5 4.4 3.4 0.8 0.6 0.1 1.3 0.3 0.5 1.0 0.6 0.5 1.0 0.1 1.4 1.1 1.2 0.5 0.8 0.8 0.6 18.0 1.2 0.6 0.6 0.4 0.8 0.4 3.5 0.9 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 4.4 0.6 0.4 0.8 0.9 71.5 1.5 94.4 3.4 3.6 35.2 1.5 1.5 1.4 35.4 5.8 664.4 1.1 2.3 1.2 83.0 0.6 0.6 0.6 1.4 0.6 0.6 0.8 0.6 0.6 0.6 0.6 0.6 3.2 0.0 2.2 0.0 2.3 1.5 1.1 0.2 0.6 0.0 1.3 0.1 0.3 5.7 1.3 0.0 0.0 0.9 302.0 0.1 9.8 0.5 0.5 0.5 0.5 2.2 0.0 24.0 0.1 0.2 0.7 1.2 0.0 1.0 1.3 0.1 8.9 1.8 1.4 0.0 0.2 0.1 0.0 9.1 6.6 1.1 0.0 2.1 12.4 2.8 3.9 0.4 963.0 0.0 0.3 0.4 0.0 0.0 12.7 0.9 0.0 0.8 0.2 0.0 0.0 0.1 0.2 0.2 2.0 0.2 1.1 0.5 80.6 0.0 0.3 3.1 KLRK1 "CD314, D12S2489E, KLR, NKG2-D, NKG2D" ENSG00000213809 "Killer cell lectin like receptor K1" P26718 12 10372353-10391874 "Cancer-related genes, CD markers, Predicted membrane proteins, Transporters" "Adaptive immunity, Differentiation, Immunity, Innate immunity" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 22.1;lymphoid tissue: 42.9" "Cell type enhanced" "Detected in some" "dendritic cells: 7.2;NK-cells: 6.2;Plasma cells: 4.5;T-cells: 22.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 40 "gdT-cell: 287.4;MAIT T-cell: 111.5;memory CD8 T-cell: 261.2;naive CD8 T-cell: 258.8;NK-cell: 335.8" "Group enriched" "Detected in all" 50 "NK-cells: 335.8;T-cells: 287.4" "Cell line enriched" "Detected in some" 9 "U-698: 64.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "CAB021896, HPA068877" Enhanced Supported "Plasma membrane" NA NA 47000 "Cluster 48: NK-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB021896: , HPA068877: AB_2686052" "unprognostic (3.34e-4)" "unprognostic (2.65e-4)" "unprognostic (3.25e-1)" "unprognostic (2.59e-2)" "unprognostic (1.53e-1)" "unprognostic (1.01e-5)" "unprognostic (5.61e-4)" "unprognostic (1.00e-3)" "unprognostic (1.33e-1)" "unprognostic (9.22e-2)" "unprognostic (1.28e-2)" "unprognostic (2.10e-2)" "unprognostic (6.56e-10)" "unprognostic (1.24e-2)" "unprognostic (6.32e-2)" "unprognostic (7.59e-2)" "unprognostic (7.08e-10)" 5.5 2.1 1.7 12.6 1.9 22.1 4.1 1.7 2.8 2.2 1.2 3.9 4.7 2.5 2.3 2.2 2.8 7.3 1.8 1.7 2.0 2.0 5.5 12.1 37.0 2.0 1.7 2.4 1.1 0.5 1.1 1.4 1.8 2.5 4.5 0.4 4.4 0.9 0.8 1.3 12.2 1.8 1.7 42.9 7.2 2.5 1.7 9.9 3.6 1.5 19.0 4.5 3.2 2.4 0.3 0.0 0.7 2.8 0.2 7.1 0.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 2.6 0.0 0.0 0.2 0.2 0.0 0.7 1.4 0.0 0.3 0.0 0.4 0.2 0.6 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.8 0.3 0.1 0.1 0.0 2.0 0.2 0.3 0.1 0.1 0.8 0.0 0.0 0.0 0.0 64.2 0.2 0.0 0.3 0.4 0.5 0.2 287.4 0.6 111.5 6.2 1.7 261.2 0.6 6.1 2.3 258.8 4.8 335.8 1.3 1.9 0.7 127.9 1.7 1.9 1.7 2.8 1.7 2.0 2.0 1.7 1.8 1.7 1.7 2.4 0.0 0.0 1.3 0.0 2.4 0.0 0.1 0.2 1.2 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.4 0.2 0.0 0.5 1.8 0.0 0.5 0.0 6.2 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 22.2 1.0 0.0 0.0 LAIR1 CD305 ENSG00000167613 "Leukocyte associated immunoglobulin like receptor 1" Q6GTX8 19 54351384-54370558 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 28.1;lymphoid tissue: 46.3" "Cell type enhanced" "Detected in many" "dendritic cells: 106.6;granulocytes: 109.3;Hofbauer cells: 190.9;Kupffer cells: 100.9;Macrophages: 128.9;NK-cells: 98.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HMC-1: 7.5;Karpas-707: 19.4;THP-1: 22.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011155 Enhanced Supported "Plasma membrane" NA NA 350000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA011155: AB_1852685" "unprognostic (1.91e-1)" "unprognostic (1.12e-2)" "unprognostic (2.81e-2)" "unprognostic (1.25e-2)" "unprognostic (2.03e-2)" "unprognostic (4.38e-2)" "unprognostic (2.16e-2)" "unprognostic (1.74e-1)" "unprognostic (5.00e-2)" "unprognostic (2.24e-1)" "unprognostic (2.21e-1)" "unprognostic (7.11e-2)" "prognostic unfavorable (5.01e-5)" "unprognostic (1.72e-1)" "unprognostic (2.72e-3)" "unprognostic (3.52e-2)" "unprognostic (5.22e-2)" 23.3 11.6 0.5 3.0 0.3 4.4 12.3 1.6 1.3 4.1 0.5 6.9 0.4 3.8 0.2 2.6 5.5 0.9 3.8 0.4 0.6 4.6 3.5 28.1 5.8 1.0 0.8 2.2 3.8 0.1 4.4 1.0 1.0 5.4 0.2 0.1 5.8 0.2 1.3 2.1 14.3 2.0 0.4 46.3 5.0 1.7 1.1 3.9 3.3 0.1 0.9 6.3 3.0 0.9 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.2 0.0 0.0 0.0 3.3 7.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 19.4 0.0 0.0 2.6 1.8 0.0 0.0 0.0 2.6 0.2 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 22.9 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.2 3.2 0.3 13.1 4.2 11.7 7.7 9.8 4.8 2.1 2.3 4.1 0.1 5.8 3.4 4.4 0.7 6.3 11.0 11.2 1.7 3.8 0.5 0.3 1.6 1.3 0.4 0.6 1.0 0.8 1.0 0.4 1.1 0.9 1.9 16.0 25.6 0.3 26.1 0.6 0.6 0.2 0.0 5.6 1.1 2.9 1.5 1.5 11.2 0.0 37.5 5.3 106.6 0.2 0.0 0.1 32.2 0.6 0.7 5.0 0.0 10.9 0.4 0.0 5.2 2.5 0.0 0.7 109.3 0.6 3.6 1.2 190.9 1.7 0.5 0.0 0.0 100.9 17.7 26.1 0.3 128.9 0.0 13.1 22.5 0.9 98.9 0.0 0.6 0.1 0.0 0.0 5.1 0.7 0.3 0.3 11.0 15.4 0.0 0.9 1.3 2.9 1.0 0.4 1.1 10.0 32.1 0.2 0.2 0.9 LAT2 "HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5" ENSG00000086730 "Linker for activation of T cells family member 2" Q9GZY6 7 74199652-74229834 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Williams-Beuren syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 61.3;lymphoid tissue: 56.6" "Cell type enhanced" "Detected in many" "B-cells: 90.6;granulocytes: 171.6;Hofbauer cells: 82.7;Kupffer cells: 71.1;Langerhans cells: 81.9;Macrophages: 89.1;monocytes: 89.6;NK-cells: 70.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 871.6" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 192.2;REH: 205.7;RPMI-8226: 73.3;THP-1: 186.5;U-937: 177.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003462 Enhanced Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA003462: AB_1079238" "unprognostic (1.24e-2)" "unprognostic (1.14e-2)" "unprognostic (1.32e-2)" "unprognostic (3.55e-3)" "unprognostic (1.09e-1)" "unprognostic (3.30e-3)" "unprognostic (2.79e-2)" "unprognostic (1.33e-1)" "unprognostic (9.27e-2)" "unprognostic (1.19e-1)" "unprognostic (6.34e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (4.10e-4)" "unprognostic (1.80e-1)" "prognostic unfavorable (6.10e-4)" "unprognostic (7.44e-2)" "unprognostic (2.03e-1)" 6.8 5.4 9.7 37.7 11.1 61.3 3.8 11.8 12.8 3.7 9.1 6.5 6.3 2.9 2.5 3.6 4.2 9.1 2.3 10.3 12.2 3.3 4.8 19.2 51.6 18.4 13.6 1.7 3.0 2.2 3.0 7.4 17.7 7.1 7.7 1.2 4.5 3.5 3.3 3.0 13.6 8.8 16.5 47.0 6.5 2.0 15.3 12.2 2.8 2.4 56.6 10.1 2.5 20.1 1.7 1.1 1.1 3.1 0.3 0.0 1.1 1.4 1.2 0.6 0.7 2.3 28.9 19.6 0.4 0.5 6.1 1.2 0.4 1.1 0.6 31.4 1.2 8.6 1.8 1.8 0.1 56.1 55.6 0.4 0.8 2.1 0.6 1.2 0.3 1.1 1.6 9.3 0.5 1.7 1.3 192.2 0.9 5.5 2.0 205.7 1.1 73.3 0.2 1.7 0.9 0.8 0.6 1.2 1.2 0.9 1.1 186.5 2.1 2.1 19.9 0.8 1.8 0.9 6.2 32.2 9.4 177.6 1.5 871.6 276.6 46.0 8.8 159.0 0.9 169.3 2.3 1.4 225.2 191.1 1.0 2.9 491.0 73.9 93.9 8.9 4.9 214.7 9.7 11.1 11.8 12.8 10.3 12.2 18.4 13.6 17.7 16.5 15.3 20.1 1.3 3.2 16.2 0.7 90.6 3.4 0.7 0.0 0.6 0.3 1.0 1.9 1.1 5.7 3.1 3.7 0.0 0.6 47.8 0.2 0.0 0.3 2.4 1.3 0.6 3.9 7.8 16.6 1.7 0.2 1.1 1.7 1.1 2.1 171.6 0.4 3.9 4.5 82.7 0.0 1.4 0.8 0.0 71.1 81.9 3.4 0.0 89.1 1.8 20.6 89.6 0.2 70.0 0.5 0.9 0.6 0.1 0.7 18.7 1.2 0.1 0.2 5.9 1.3 0.0 1.9 0.9 0.4 1.4 0.1 2.6 1.2 27.7 0.3 0.8 0.4 LGALS4 GAL4 ENSG00000171747 "Galectin 4" P56470 19 38801671-38812945 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "intestine: 1307.1" "Group enriched" "Detected in many" 4 "Distal enterocytes: 4349.4;Intestinal goblet cells: 3767.6;Paneth cells: 3353.0;Proximal enterocytes: 4572.2;Undifferentiated cells: 2684.6" "Group enriched" "Detected in many" 21 "colorectal cancer: 450.7;liver cancer: 133.6;pancreatic cancer: 213.7;stomach cancer: 190.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 205 "OE19: 987.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "CAB025653, HPA031184, HPA031185, HPA031186" Enhanced Uncertain "Plasma membrane" NA NA 200000 "Cluster 9: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB025653: , HPA031184: AB_2673776, HPA031185: AB_2673777, HPA031186: AB_2673778" "unprognostic (1.11e-1)" "unprognostic (1.12e-1)" "unprognostic (2.57e-3)" "unprognostic (7.88e-2)" "unprognostic (1.12e-1)" "unprognostic (1.61e-2)" "unprognostic (5.01e-2)" "unprognostic (5.34e-2)" "unprognostic (1.54e-1)" "unprognostic (7.58e-2)" "unprognostic (3.80e-2)" "unprognostic (1.48e-2)" "prognostic unfavorable (2.28e-4)" "unprognostic (1.69e-1)" "unprognostic (3.38e-1)" "unprognostic (9.71e-2)" "prognostic favorable (3.21e-4)" 1.6 0.5 0.3 86.1 0.4 0.5 5.5 0.5 0.6 1.4 0.2 1307.1 812.2 3.2 0.2 1.4 2.4 137.1 0.9 0.3 0.3 2.9 79.5 1.2 1.1 0.3 0.3 1.6 31.5 0.0 0.8 0.2 0.3 2.3 933.0 0.2 1.1 2.3 1.6 1.6 691.9 55.2 0.2 4.0 135.2 0.9 0.3 0.3 1.7 0.2 0.4 11.2 1.5 0.4 0.0 0.4 0.1 0.0 0.3 0.0 1.3 0.0 0.0 0.0 0.0 1.3 0.1 0.3 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 2.2 0.0 987.1 0.0 0.1 0.0 2.5 0.1 4.8 0.2 1.4 0.1 0.1 0.0 0.0 0.1 1.0 0.0 0.0 0.2 1.0 0.0 0.2 0.2 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.5 0.6 0.3 0.3 0.3 0.3 0.3 0.2 0.3 0.4 1.7 3.2 6.5 0.7 10.3 1.1 3.0 0.6 3.4 1.1 3.6 3.0 1.3 770.7 1.0 0.0 0.0 0.8 0.9 4349.4 0.0 267.1 0.2 1.9 1.8 1.2 649.7 0.0 0.3 103.3 0.5 0.8 310.4 5.7 49.0 0.8 1.8 69.0 0.1 1.7 0.3 3767.6 0.0 1.9 0.3 0.0 0.0 1.2 0.0 1.0 3.0 0.8 1.0 0.0 0.7 492.7 3353.0 0.4 0.7 1.8 4572.2 9.3 0.4 2.3 0.0 3.9 1.1 0.3 0.9 0.9 2.7 0.5 11.1 1.1 2684.6 42.4 LGALS8 PCTA-1 ENSG00000116977 "Galectin 8" O00214 1 236518000-236552981 "Predicted intracellular proteins" Autophagy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 322.8;Late spermatids: 222.6;Syncytiotrophoblasts: 176.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 118.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012734, HPA030491" Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 34: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "HPA012734: AB_2668720, HPA030491: AB_10602345" "unprognostic (2.03e-2)" "unprognostic (1.54e-1)" "unprognostic (2.38e-2)" "unprognostic (3.80e-3)" "unprognostic (2.02e-3)" "unprognostic (4.71e-3)" "unprognostic (3.93e-2)" "prognostic favorable (9.40e-4)" "unprognostic (9.96e-2)" "unprognostic (1.41e-1)" "unprognostic (2.12e-1)" "unprognostic (1.78e-3)" "prognostic unfavorable (4.93e-7)" "unprognostic (1.41e-1)" "unprognostic (1.57e-1)" "unprognostic (3.15e-2)" "unprognostic (8.21e-2)" 28.6 14.3 10.8 26.5 11.3 44.4 23.3 12.4 14.1 17.2 11.5 19.9 21.6 16.7 19.6 21.2 13.8 24.8 55.0 12.5 12.6 23.4 49.5 27.0 24.0 12.9 10.9 21.6 21.8 35.0 12.7 41.0 13.5 22.2 19.9 22.9 22.1 21.3 6.8 32.4 24.1 21.8 11.7 42.6 18.9 57.1 11.4 26.3 17.2 9.4 22.8 32.8 15.3 11.7 52.3 27.5 3.6 20.8 46.6 39.0 55.6 38.0 45.4 49.0 59.3 37.6 63.3 1.5 34.8 33.7 26.8 60.3 11.0 54.7 43.2 31.1 7.3 35.5 20.7 68.1 56.9 46.9 78.9 39.6 45.6 41.0 13.8 42.4 52.5 26.4 40.7 25.1 35.7 33.3 23.2 8.4 12.5 4.1 18.5 27.2 0.8 3.0 35.4 80.8 13.1 25.7 24.4 82.3 13.7 2.1 59.0 33.7 39.1 1.0 22.0 29.9 47.7 10.0 7.4 1.0 50.4 65.7 30.9 118.5 37.4 18.7 12.5 32.9 17.8 10.7 18.4 14.1 31.7 6.8 12.2 12.7 16.1 14.2 24.0 14.2 22.5 24.8 10.8 11.3 12.4 14.1 12.5 12.6 12.9 10.9 13.5 11.7 11.4 11.7 44.0 76.9 54.7 12.1 19.3 32.5 28.5 64.9 44.9 28.1 31.7 22.7 55.2 34.3 68.1 14.7 25.0 64.4 33.9 25.3 5.9 61.8 322.8 18.7 21.9 39.9 18.1 19.0 31.5 39.2 53.5 35.2 23.0 20.8 109.4 38.0 46.1 27.1 57.5 38.7 37.0 18.8 57.0 100.5 23.6 222.6 23.6 45.1 7.2 24.4 38.7 6.5 17.5 18.1 16.7 44.0 36.0 13.9 15.1 20.6 26.4 14.5 53.1 19.4 26.3 22.5 19.6 46.8 8.7 21.3 37.1 176.2 34.4 22.8 17.1 24.4 LINGO1 "FLJ14594, LERN1, LRRN6A" ENSG00000169783 "Leucine rich repeat and Ig domain containing 1" Q96FE5 15 77613027-77820900 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.1" "Group enriched" "Detected in many" 4 "Astrocytes: 271.0;Excitatory neurons: 271.6;Horizontal cells: 132.9;Inhibitory neurons: 220.5;Microglial cells: 167.7;Oligodendrocyte precursor cells: 240.8;Oligodendrocytes: 324.2" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 37.4;basal ganglia: 43.9;cerebral cortex: 56.1;hippocampal formation: 49.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 23.9;AN3-CA: 20.1;HAP1: 30.2;HEK 293: 21.0;MCF7: 13.5;NTERA-2: 56.9;SuSa: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074653 Enhanced Supported "Plasma membrane" NA NA 25000 "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA074653: AB_2686706" "unprognostic (1.06e-1)" "unprognostic (7.07e-2)" "unprognostic (2.16e-2)" "unprognostic (1.48e-2)" "unprognostic (3.09e-1)" "unprognostic (2.20e-1)" "unprognostic (2.84e-2)" "unprognostic (3.77e-2)" "unprognostic (3.40e-1)" "unprognostic (1.10e-1)" "unprognostic (7.36e-2)" "unprognostic (2.74e-2)" "prognostic unfavorable (3.23e-7)" "unprognostic (2.07e-1)" "unprognostic (7.06e-2)" "unprognostic (2.85e-1)" "unprognostic (2.59e-2)" 3.9 1.1 37.4 1.2 43.9 0.0 3.5 0.0 56.1 4.6 0.0 2.2 1.5 4.5 2.2 0.9 2.7 2.1 11.8 49.1 0.0 4.2 0.8 1.0 0.7 0.0 0.0 2.3 2.5 4.1 1.9 6.7 0.0 1.6 0.8 16.2 3.2 2.0 0.8 2.8 1.7 4.6 0.0 3.3 1.4 5.3 0.2 0.3 2.2 1.4 0.3 2.3 2.9 4.6 0.0 2.1 23.9 20.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 1.4 0.0 0.4 0.1 30.2 0.0 0.0 0.0 21.0 0.0 0.0 0.4 0.3 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 0.0 3.3 0.2 0.0 13.5 0.0 0.0 56.9 1.3 0.0 0.0 0.0 0.5 0.0 0.0 4.2 1.2 0.1 2.4 4.9 21.6 0.3 0.4 2.1 0.0 5.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 37.4 43.9 0.0 56.1 49.1 0.0 0.0 0.0 0.0 0.0 0.2 4.6 2.1 0.0 0.0 271.0 0.0 0.3 0.1 0.0 0.0 21.8 0.7 0.3 7.3 1.5 0.0 0.0 2.1 0.1 0.0 1.8 0.0 0.3 8.6 0.8 3.7 2.3 0.0 0.0 271.6 0.2 0.2 1.8 0.0 0.2 0.0 14.9 4.2 0.0 0.3 132.9 220.5 0.3 0.0 0.0 0.0 16.5 0.3 0.1 3.6 167.7 0.0 51.1 0.0 240.8 324.2 0.2 7.7 0.4 0.0 0.0 0.0 0.0 0.0 19.5 26.3 0.0 21.9 0.2 3.1 0.0 0.1 0.3 0.1 0.5 0.2 0.0 LIPI "CT17, LPDL, mPA-PLA1beta, PLA1C, PRED5" ENSG00000188992 "Lipase I" Q6XZB0 21 14108813-14210955 "Disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Lipid degradation, Lipid metabolism" "Heparin-binding, Hydrolase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 167 "epididymis: 421.0" "Group enriched" "Detected in some" 4 "Early spermatids: 1.7;Excitatory neurons: 1.5;Inhibitory neurons: 2.0;Microglial cells: 1.9;Oligodendrocyte precursor cells: 2.0" "Cancer enriched" "Detected in single" 6 "thyroid cancer: 0.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA049665 Supported "Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA049665: " "unprognostic (2.60e-2)" "unprognostic (3.49e-1)" "unprognostic (1.12e-3)" "unprognostic (1.14e-1)" "unprognostic (1.08e-2)" "unprognostic (1.19e-1)" "unprognostic (2.05e-2)" "unprognostic (1.68e-1)" "unprognostic (4.53e-2)" "unprognostic (2.90e-1)" "unprognostic (3.64e-13)" "unprognostic (2.82e-1)" "unprognostic (4.14e-2)" "unprognostic (2.90e-1)" "unprognostic (7.87e-3)" 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.2 0.0 0.5 421.0 0.2 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.6 0.1 0.4 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 LIPJ "bA425M17.2, LIPL1" ENSG00000204022 "Lipase family member J" Q5W064 10 88586753-88606976 "Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 6 "testis: 7.0" "Cell type enriched" "Detected in some" 7 "Early spermatids: 67.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA048594 Uncertain Approved "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA048594: AB_2680456" "unprognostic (4.79e-3)" "unprognostic (6.77e-2)" "unprognostic (4.80e-2)" "unprognostic (2.36e-1)" "unprognostic (2.70e-2)" "unprognostic (9.33e-2)" "unprognostic (2.90e-3)" "unprognostic (7.50e-2)" "unprognostic (1.65e-1)" "unprognostic (1.09e-1)" "unprognostic (4.73e-2)" "unprognostic (1.73e-2)" "unprognostic (6.21e-4)" "unprognostic (9.87e-2)" "unprognostic (9.57e-2)" "unprognostic (1.85e-1)" "unprognostic (1.88e-1)" 0.2 0.0 0.2 0.1 0.2 0.0 0.2 1.0 0.3 0.1 0.3 0.1 0.3 0.1 0.9 0.0 0.7 0.1 0.1 0.3 0.3 0.2 0.5 0.1 0.3 1.2 0.5 0.1 0.4 0.0 0.1 0.0 0.5 0.3 0.2 0.1 0.3 0.1 0.3 0.1 0.1 0.2 0.4 0.1 0.2 7.0 0.3 0.4 0.6 0.0 0.3 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 1.0 0.3 0.3 0.3 1.2 0.5 0.5 0.4 0.3 0.3 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.9 0.1 67.6 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.0 0.0 0.6 0.0 9.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 LOXHD1 "DFNB77, FLJ32670, LH2D1" ENSG00000167210 "Lipoxygenase homology domains 1" Q8IVV2 18 46476972-46657220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 7.2;kidney: 6.9;testis: 23.0" "Group enriched" "Detected in some" 70 "Early spermatids: 199.3;Late spermatids: 439.4" "Cancer enhanced" "Detected in single" "testis cancer: 0.5" "Region enhanced" "Detected in some" "basal ganglia: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA077128 Approved "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA077128: " "unprognostic (6.95e-2)" "unprognostic (1.88e-2)" "unprognostic (4.81e-3)" "unprognostic (2.65e-1)" "unprognostic (1.30e-2)" "unprognostic (7.75e-4)" "unprognostic (9.53e-2)" "unprognostic (7.91e-2)" "unprognostic (7.61e-2)" "unprognostic (9.44e-2)" "unprognostic (1.26e-2)" "unprognostic (1.93e-2)" "unprognostic (7.43e-3)" "unprognostic (6.48e-5)" "unprognostic (2.30e-1)" "unprognostic (8.10e-3)" "unprognostic (1.66e-3)" 2.3 0.0 0.5 0.0 3.4 2.8 0.6 0.0 2.1 0.0 0.1 0.1 0.0 0.1 7.2 0.0 1.7 0.2 0.9 0.3 0.0 6.9 0.0 1.0 0.0 0.0 0.1 0.1 0.2 0.2 1.9 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.1 0.0 0.0 0.8 0.1 23.0 0.3 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 3.4 0.0 2.1 0.3 0.0 0.0 0.1 0.0 0.0 0.3 0.9 1.2 3.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 199.3 0.0 0.1 0.9 0.0 0.0 4.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 3.6 0.0 0.0 0.0 0.0 439.4 1.8 0.3 0.0 0.0 0.3 0.0 0.0 1.5 0.6 0.0 0.0 2.2 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 4.5 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 LPAR3 "Edg-7, EDG7, HOFNH30, LP-A3, LPA3, RP4-678I3" ENSG00000171517 "Lysophosphatidic acid receptor 3" Q9UBY5 1 84811602-84893206 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 36.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 15.6;Cardiomyocytes: 31.2;Endometrial ciliated cells: 36.9;Glandular and luminal cells: 51.6;Respiratory ciliated cells: 18.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 24.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 19.0;HBEC3-KT: 22.2;hTCEpi: 25.0;NTERA-2: 20.3;PC-3: 19.0;SK-MEL-30: 24.1" "Low region specificity" "Detected in some" "Not detected" "Not detected" HPA013421 Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA013421: AB_1847990" "unprognostic (2.85e-2)" "unprognostic (1.67e-1)" "unprognostic (2.66e-1)" "unprognostic (4.42e-1)" "unprognostic (2.72e-2)" "unprognostic (6.46e-3)" "unprognostic (1.15e-1)" "unprognostic (1.29e-2)" "unprognostic (1.20e-1)" "prognostic favorable (4.31e-5)" "unprognostic (1.11e-2)" "unprognostic (7.52e-2)" "unprognostic (1.13e-4)" "unprognostic (4.11e-2)" "unprognostic (1.19e-1)" "unprognostic (4.27e-2)" "unprognostic (5.43e-2)" 0.0 1.3 2.4 0.2 3.3 0.3 0.9 2.1 5.1 10.4 2.0 0.5 0.1 2.9 5.9 7.0 36.4 0.5 10.5 3.8 1.7 0.0 0.1 1.5 0.2 8.2 2.7 1.5 10.4 0.1 0.1 1.4 2.6 13.4 0.6 0.1 5.7 1.0 0.4 4.3 0.1 0.1 1.9 0.1 0.3 10.4 2.3 2.3 0.2 0.0 1.0 5.1 5.3 3.2 0.7 0.1 0.0 0.1 0.0 0.0 0.7 0.3 1.7 1.4 1.1 0.0 0.0 0.1 0.3 0.0 0.0 0.4 19.0 22.2 1.4 0.2 3.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 25.0 4.8 1.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 20.3 0.0 19.0 0.0 0.0 0.0 0.0 5.8 1.3 1.1 0.0 0.5 24.1 1.4 0.0 2.0 0.1 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 2.4 3.3 2.1 5.1 3.8 1.7 8.2 2.7 2.6 1.9 2.3 3.2 0.0 0.0 0.5 12.7 0.0 3.4 15.6 5.6 7.4 0.0 1.8 3.7 31.2 0.0 6.5 0.0 0.0 0.5 0.1 0.3 0.0 0.0 2.9 36.9 3.6 0.5 0.0 0.0 0.2 1.3 0.0 1.2 0.0 51.6 0.0 0.5 0.4 0.0 0.4 0.0 0.1 0.2 2.0 0.0 1.5 2.4 0.6 0.7 1.8 1.9 0.0 0.0 0.0 0.0 0.1 1.0 0.3 0.0 0.0 13.1 0.0 0.0 18.7 0.0 0.0 0.0 1.2 0.7 3.4 7.7 9.1 0.1 1.5 0.6 0.4 13.5 LRCH2 KIAA1495 ENSG00000130224 "Leucine rich repeats and calponin homology domain containing 2" Q5VUJ6 X 115110616-115234096 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 23.8;Excitatory neurons: 24.4;Inhibitory neurons: 38.0;Oligodendrocyte precursor cells: 48.2;Oligodendrocytes: 32.0;Sertoli cells: 26.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HAP1: 21.4;U-266/70: 14.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003233, HPA076892" Approved Approved "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA003233: AB_2265929, HPA076892: " "unprognostic (9.74e-2)" "unprognostic (9.48e-2)" "unprognostic (1.14e-2)" "unprognostic (4.22e-5)" "unprognostic (2.88e-2)" "unprognostic (1.17e-1)" "unprognostic (1.42e-1)" "unprognostic (9.39e-2)" "unprognostic (1.34e-1)" "unprognostic (1.43e-1)" "unprognostic (1.01e-2)" "unprognostic (1.84e-1)" "unprognostic (4.29e-5)" "unprognostic (1.09e-3)" "unprognostic (1.34e-1)" "unprognostic (7.75e-2)" "unprognostic (1.16e-2)" 2.7 4.4 3.9 1.4 4.1 0.0 2.0 4.2 4.7 5.2 0.6 8.2 0.5 5.1 2.1 1.6 3.4 2.6 2.6 4.0 6.8 1.1 0.2 2.8 0.7 3.3 3.8 7.0 0.5 0.3 4.4 7.5 3.5 8.3 1.9 3.6 0.5 7.3 0.5 0.5 2.0 5.1 3.9 1.8 2.0 2.1 6.2 0.5 2.3 1.5 0.2 4.9 3.3 4.3 0.0 0.0 6.4 4.7 6.4 5.3 0.0 4.3 9.2 4.1 9.3 0.0 0.0 0.1 0.1 5.7 3.2 0.3 21.4 0.0 6.2 0.0 5.8 0.0 0.0 0.0 5.1 0.0 0.1 3.1 0.0 1.6 0.3 10.8 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 6.2 0.0 4.6 0.0 5.1 0.6 0.0 8.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 2.5 0.1 6.0 14.0 2.5 0.0 1.7 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 4.1 4.2 4.7 4.0 6.8 3.3 3.8 3.5 3.9 6.2 4.3 9.3 3.2 12.3 23.8 0.0 0.6 0.1 0.0 0.6 6.9 0.1 0.3 7.5 0.0 0.0 1.8 0.0 0.1 0.0 0.0 1.9 0.0 9.1 0.1 5.9 6.7 0.0 0.0 24.4 0.0 0.2 6.3 0.0 0.1 0.0 8.4 2.9 0.0 0.6 1.7 38.0 0.0 0.0 0.0 1.0 2.9 8.7 0.1 1.8 9.4 0.0 6.4 0.0 48.2 32.0 0.0 0.0 6.4 0.0 1.2 0.0 0.0 0.0 2.5 26.3 3.6 7.8 5.4 2.9 0.0 0.1 0.3 0.2 5.7 0.0 0.1 LRFN2 "FIGLER2, KIAA1246, SALM1" ENSG00000156564 "Leucine rich repeat and fibronectin type III domain containing 2" Q9ULH4 6 40391591-40587364 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 6.4;retina: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 24.2;Cone photoreceptor cells: 62.6;Excitatory neurons: 111.5;Inhibitory neurons: 62.8;Oligodendrocyte precursor cells: 49.8" "Not detected" "Not detected" "Region enhanced" "Detected in many" "basal ganglia: 6.4;cerebral cortex: 5.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 1.7;SH-SY5Y: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA076660 Enhanced Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA076660: AB_2686812" "unprognostic (1.93e-2)" "unprognostic (2.04e-1)" "unprognostic (3.61e-2)" "unprognostic (4.58e-4)" "unprognostic (3.10e-1)" "unprognostic (1.21e-1)" "unprognostic (2.69e-1)" "unprognostic (5.75e-3)" "unprognostic (4.94e-2)" "unprognostic (1.80e-1)" "unprognostic (9.05e-2)" "unprognostic (1.35e-1)" "unprognostic (1.51e-1)" "unprognostic (1.64e-1)" "unprognostic (2.98e-1)" "unprognostic (1.16e-1)" "unprognostic (2.66e-4)" 0.0 0.3 1.6 0.0 6.4 0.3 0.0 0.0 5.9 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 0.2 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 1.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 1.7 0.0 0.0 0.0 0.1 0.7 4.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 1.6 6.4 0.0 5.9 1.3 0.0 0.0 0.0 0.0 0.0 0.4 1.3 0.0 0.0 0.0 24.2 0.0 0.0 0.0 0.0 0.0 10.8 0.1 0.3 0.6 0.0 0.1 0.0 62.6 0.4 0.3 0.1 0.0 0.0 1.5 0.0 0.0 0.1 4.2 0.0 111.5 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 62.8 1.0 0.0 0.0 0.0 1.5 0.3 0.0 0.0 3.7 0.0 0.8 0.0 49.8 2.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 9.6 0.0 0.0 0.0 1.9 0.0 1.0 0.0 0.3 0.2 0.0 0.1 0.1 LRRC69 ENSG00000214954 "Leucine rich repeat containing 69" Q6ZNQ3 8 91101832-91219236 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 2.9" "Cell type enhanced" "Detected in many" "Early spermatids: 77.3;Late spermatids: 18.0;Microglial cells: 27.2;Oligodendrocytes: 27.9" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEK 293: 6.3;SuSa: 5.2;U-266/70: 16.0;U-266/84: 9.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046337 Uncertain Approved "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA046337: AB_2679626" "unprognostic (1.63e-2)" "unprognostic (1.02e-1)" "unprognostic (4.69e-1)" "unprognostic (3.28e-1)" "unprognostic (2.78e-1)" "unprognostic (3.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.50e-2)" "unprognostic (2.49e-2)" "unprognostic (1.47e-1)" "unprognostic (9.18e-2)" "unprognostic (1.88e-1)" "unprognostic (3.09e-6)" "unprognostic (6.91e-2)" "unprognostic (1.60e-1)" "unprognostic (1.43e-1)" "unprognostic (8.68e-5)" 0.3 0.5 0.2 0.9 0.6 0.1 0.6 0.6 0.4 0.3 0.8 0.3 0.2 0.2 0.9 0.3 0.2 0.4 0.5 0.2 0.4 0.5 0.3 0.4 1.1 0.8 0.5 0.2 0.3 0.9 0.2 0.4 0.8 0.5 0.7 0.6 0.7 0.3 0.5 1.7 0.4 0.8 0.5 0.7 0.4 2.9 0.5 0.8 0.5 0.4 0.7 0.7 0.3 1.0 0.6 0.6 0.1 0.4 0.6 1.3 1.0 0.3 0.1 0.2 0.3 0.9 0.8 0.9 0.4 0.2 0.1 0.6 0.7 1.1 0.3 0.3 6.3 1.4 1.8 0.4 0.2 0.5 1.0 0.4 1.0 0.4 0.7 0.4 0.1 1.1 1.0 0.5 0.4 0.2 0.3 0.4 0.6 1.0 0.4 0.8 0.0 0.7 0.2 0.7 0.0 0.2 0.0 0.4 1.0 5.2 1.4 1.0 0.5 0.2 0.6 0.1 0.8 16.0 9.5 3.8 0.1 2.1 0.8 0.2 0.1 0.3 0.2 0.2 0.2 0.2 0.3 0.1 0.0 0.4 0.4 0.2 0.0 0.1 0.1 0.4 0.5 0.0 0.2 0.6 0.6 0.4 0.2 0.4 0.8 0.5 0.8 0.5 0.5 1.0 1.1 0.0 1.1 16.0 1.5 4.7 2.9 1.3 0.6 1.9 1.6 0.6 2.9 0.0 1.5 3.7 4.2 2.3 2.0 1.1 3.9 1.5 77.3 1.2 0.4 2.7 2.4 0.8 5.3 1.2 1.9 1.7 0.0 0.6 0.0 1.0 4.2 0.6 0.9 0.0 6.4 2.2 6.1 1.3 7.0 18.0 2.8 1.6 7.2 27.2 4.2 1.1 2.1 7.5 27.9 1.8 1.6 1.2 0.2 5.3 0.4 0.9 6.1 3.2 0.0 4.7 2.7 4.2 4.0 0.7 5.3 1.0 2.2 0.9 1.7 2.3 LSR "ILDR3, LISCH7" ENSG00000105699 "Lipolysis stimulated lipoprotein receptor" Q86X29 19 35248330-35267964 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 144.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 335.6;Ductal cells: 260.5;Exocrine glandular cells: 278.9;Pancreatic endocrine cells: 336.0;Paneth cells: 273.6;Syncytiotrophoblasts: 248.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 500.5;CACO-2: 215.6;CAPAN-2: 225.3;HaCaT: 203.9;OE19: 300.4;RT4: 198.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007270, HPA075309" Approved Supported "Plasma membrane" NA NA 3500000 "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA007270: AB_1079253, HPA075309: " "unprognostic (3.90e-1)" "unprognostic (1.12e-1)" "unprognostic (2.34e-2)" "unprognostic (2.67e-3)" "unprognostic (2.28e-2)" "unprognostic (6.07e-3)" "unprognostic (1.55e-1)" "unprognostic (9.84e-2)" "unprognostic (2.17e-1)" "unprognostic (2.70e-2)" "unprognostic (2.23e-2)" "unprognostic (3.42e-2)" "prognostic favorable (8.09e-4)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.99e-2)" "unprognostic (1.54e-2)" 15.7 31.3 15.7 17.8 13.6 3.6 25.4 13.2 14.7 20.4 39.0 96.9 85.0 14.4 13.9 60.0 29.7 36.4 7.7 12.5 13.2 28.9 144.8 30.0 14.4 17.1 14.8 6.4 114.2 16.8 27.3 46.9 15.5 25.6 43.7 8.6 69.4 18.5 4.4 51.9 75.0 5.3 12.9 17.9 133.1 27.2 17.7 6.6 32.9 2.7 14.1 29.9 29.3 14.8 500.5 8.1 0.7 1.0 1.4 0.5 86.8 1.2 1.9 2.2 1.6 215.6 225.3 19.6 73.0 1.3 7.2 203.9 44.3 75.0 0.3 30.1 82.6 0.2 6.5 96.1 1.7 0.3 0.9 1.0 81.2 2.0 24.2 1.0 0.8 0.6 80.2 17.2 1.1 177.4 0.9 1.1 69.0 300.4 3.2 3.8 0.8 54.6 46.2 198.2 37.7 1.4 40.9 130.5 35.8 21.7 112.5 2.6 0.4 3.9 44.7 3.1 2.2 27.2 52.5 45.7 3.4 0.8 12.4 6.4 0.2 0.1 2.5 0.0 2.6 4.3 5.8 5.4 0.1 3.0 4.2 4.9 0.0 5.6 0.0 0.2 4.1 2.9 15.7 13.6 13.2 14.7 12.5 13.2 17.1 14.8 15.5 12.9 17.7 14.8 38.2 16.0 21.7 0.3 26.3 51.7 123.4 90.7 50.1 2.1 60.9 49.7 5.6 78.6 71.2 36.8 16.7 210.3 4.7 335.6 11.7 260.5 9.4 41.7 27.4 44.6 56.4 3.2 0.8 278.9 93.0 11.9 214.1 61.5 31.1 30.3 20.3 89.7 21.7 0.0 0.9 145.5 73.2 2.2 14.3 2.9 6.5 4.6 14.2 22.5 7.2 11.5 3.1 1.5 0.8 336.0 273.6 3.4 41.1 113.6 117.8 24.6 43.8 12.3 0.0 4.1 24.4 7.9 19.1 57.2 51.7 248.0 24.3 3.4 124.2 206.3 MAP4K1 HPK1 ENSG00000104814 "Mitogen-activated protein kinase kinase kinase kinase 1" Q92918 19 38587641-38618882 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.1;lymphoid tissue: 56.9" "Cell type enhanced" "Detected in many" "B-cells: 42.6;dendritic cells: 42.6;Langerhans cells: 27.8;Plasma cells: 30.4;Rod photoreceptor cells: 77.9;T-cells: 43.6" "Cancer enhanced" "Detected in all" "testis cancer: 15.2" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 45.2;HDLM-2: 46.4;Karpas-707: 46.9;REH: 25.5;RPMI-8226: 29.8;U-266/70: 36.0;U-266/84: 38.2;U-698: 57.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007419, CAB007754" Enhanced Approved "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "CAB007754: AB_562299, HPA007419: AB_1853778" "unprognostic (1.99e-3)" "prognostic favorable (6.17e-5)" "unprognostic (9.50e-3)" "unprognostic (3.27e-1)" "unprognostic (6.03e-2)" "prognostic favorable (3.26e-4)" "unprognostic (4.88e-3)" "unprognostic (5.32e-3)" "unprognostic (2.79e-1)" "unprognostic (2.51e-1)" "unprognostic (3.92e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (7.99e-10)" "unprognostic (1.72e-1)" "unprognostic (1.83e-1)" "unprognostic (3.18e-2)" "unprognostic (1.50e-2)" 2.7 1.5 0.6 14.6 0.7 9.2 1.7 0.7 1.2 1.6 0.7 5.0 2.7 1.3 0.8 2.8 1.8 2.3 1.7 0.7 0.8 2.7 3.0 6.2 32.2 1.0 0.8 0.9 1.2 0.2 1.8 1.8 0.9 2.5 2.3 16.1 2.8 0.5 0.8 1.9 30.1 0.9 0.8 56.9 3.1 1.5 0.9 13.1 3.2 0.2 29.3 2.9 2.1 0.9 0.2 0.3 0.2 0.6 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 45.2 0.7 0.0 0.0 0.1 0.1 0.0 0.0 46.4 0.3 9.8 0.1 0.1 0.0 3.1 0.5 0.1 0.0 0.0 0.0 0.0 0.0 21.3 0.2 46.9 0.1 0.3 11.0 12.0 1.4 0.3 0.1 25.5 0.1 29.8 0.0 0.0 0.4 0.1 0.1 0.2 0.1 0.3 0.2 10.8 0.1 0.1 0.3 0.1 0.1 36.0 38.2 57.8 0.0 13.5 0.1 2.9 4.9 2.0 18.9 9.4 17.4 22.7 15.8 20.1 23.9 15.5 8.6 12.1 0.5 6.1 5.7 22.2 22.2 12.1 0.6 0.7 0.7 1.2 0.7 0.8 1.0 0.8 0.9 0.8 0.9 0.9 0.7 3.2 4.9 0.3 42.6 2.3 0.2 0.4 1.2 6.7 0.7 1.0 0.9 0.0 0.6 0.0 12.5 0.2 42.6 0.1 0.0 0.0 0.0 0.3 0.2 1.6 0.0 5.5 0.7 0.2 0.3 1.5 2.0 0.3 15.8 0.4 1.1 1.1 2.6 1.7 1.0 0.1 0.0 8.8 27.8 0.2 0.0 11.6 3.6 1.9 10.3 11.5 15.5 1.0 0.5 0.0 0.0 0.0 30.4 0.3 0.0 0.2 0.0 77.9 0.0 1.0 0.4 0.7 6.4 0.6 1.0 0.1 43.6 0.3 0.3 0.1 MAP6 "FLJ41346, KIAA1878, MAP6-N, STOP" ENSG00000171533 "Microtubule associated protein 6" Q96JE9 11 75586918-75669038 "Predicted intracellular proteins" Transport Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 76.8;retina: 96.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 81.2;Cone photoreceptor cells: 158.4;Excitatory neurons: 75.8;Horizontal cells: 50.5;Inhibitory neurons: 43.3;Late spermatids: 41.9" "Cancer enhanced" "Detected in many" "glioma: 9.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "AF22: 37.8;CACO-2: 38.1;HDLM-2: 21.5;SCLC-21H: 62.4;SH-SY5Y: 31.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015442, CAB022600, HPA039061, HPA039062" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "CAB015442: AB_2140997, CAB022600: , HPA039061: AB_2676325, HPA039062: AB_2676326" "unprognostic (3.04e-2)" "unprognostic (6.18e-2)" "unprognostic (3.15e-2)" "unprognostic (9.07e-2)" "unprognostic (7.54e-2)" "unprognostic (4.49e-2)" "unprognostic (8.29e-2)" "unprognostic (2.51e-2)" "unprognostic (5.99e-2)" "unprognostic (7.99e-2)" "prognostic favorable (3.41e-4)" "prognostic favorable (9.15e-4)" "unprognostic (2.43e-2)" "unprognostic (3.96e-3)" "unprognostic (8.09e-3)" "unprognostic (1.77e-1)" "unprognostic (2.03e-1)" 4.8 19.0 68.3 2.0 68.0 0.0 3.5 50.7 70.6 10.6 64.4 23.0 1.7 18.1 21.0 4.2 40.7 6.4 8.6 67.7 71.5 17.0 1.2 7.8 0.7 70.2 64.6 8.0 3.6 22.0 76.8 1.5 70.8 17.8 3.5 96.1 3.6 21.1 1.0 8.1 4.8 13.1 52.9 2.4 10.7 18.6 68.5 0.8 7.9 1.3 0.5 7.1 8.4 59.7 0.2 0.7 37.8 0.1 0.1 0.0 0.0 3.8 0.2 0.3 0.0 38.1 0.1 0.6 1.4 6.3 1.3 0.0 3.4 0.5 0.0 21.5 0.5 0.0 0.0 0.0 1.0 0.0 0.0 2.1 0.5 0.1 0.2 5.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 5.9 0.0 2.9 0.0 0.0 0.1 0.1 0.5 62.4 31.7 4.6 0.0 0.0 0.8 0.0 0.0 0.9 0.0 0.1 0.1 0.5 0.0 0.0 0.0 6.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 68.3 68.0 50.7 70.6 67.7 71.5 70.2 64.6 70.8 52.9 68.5 59.7 1.2 3.2 3.7 25.8 0.1 0.8 1.7 0.7 0.0 81.2 0.8 1.8 8.4 1.5 3.1 11.0 158.4 0.2 0.2 0.0 1.9 0.1 27.7 28.2 4.6 1.6 13.1 0.0 75.8 0.2 0.0 2.9 0.0 0.8 0.0 0.8 2.2 0.3 0.1 50.5 43.3 0.0 6.1 0.0 1.1 41.9 7.5 0.3 5.4 1.9 0.0 18.7 0.0 13.0 13.3 0.2 0.0 18.4 0.1 1.4 0.0 1.2 25.4 10.2 0.0 1.9 5.7 23.5 4.3 0.1 0.4 0.0 0.3 0.1 0.0 0.4 MAPK8IP1 "IB1, JIP-1, JIP1, PRKM8IP" ENSG00000121653 "Mitogen-activated protein kinase 8 interacting protein 1" Q9UQF2 11 45885651-45906465 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Diabetes mellitus, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 166.8;pituitary gland: 118.2" "Cell type enhanced" "Detected in many" "Early spermatids: 43.8;Enteroendocrine cells: 40.2;Horizontal cells: 67.3;Late spermatids: 39.2;Muller glia cells: 41.3;Oligodendrocytes: 48.7" "Cancer enhanced" "Detected in all" "glioma: 51.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SCLC-21H: 76.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058921, HPA070332, HPA079657" Approved Enhanced "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA058921: AB_2683854, HPA070332: AB_2686254, HPA079657: " "unprognostic (3.96e-2)" "unprognostic (8.73e-2)" "unprognostic (1.08e-1)" "unprognostic (6.88e-2)" "unprognostic (5.59e-2)" "unprognostic (2.82e-1)" "unprognostic (8.25e-3)" "unprognostic (3.42e-3)" "unprognostic (1.27e-2)" "unprognostic (9.54e-2)" "unprognostic (3.22e-3)" "unprognostic (2.20e-2)" "prognostic favorable (1.23e-11)" "unprognostic (7.19e-2)" "unprognostic (4.01e-2)" "unprognostic (4.46e-2)" "unprognostic (1.80e-3)" 4.8 23.3 127.9 2.3 131.0 1.3 4.8 122.0 147.7 8.2 29.6 8.3 1.4 10.9 3.5 2.2 11.3 3.5 5.5 166.8 120.6 11.5 5.6 4.0 0.6 154.9 130.9 9.1 43.1 19.2 118.2 1.4 142.6 11.6 1.2 11.5 11.4 6.1 2.4 4.0 3.7 5.7 124.6 2.3 9.0 27.7 139.3 1.0 7.0 2.5 0.4 6.7 4.8 164.4 0.0 7.1 9.4 26.2 3.4 1.8 0.3 5.1 4.6 9.9 7.2 6.3 1.1 0.4 2.5 5.9 16.8 5.8 10.2 4.8 4.4 4.0 13.1 0.1 8.6 4.1 3.1 0.6 4.4 2.4 1.0 6.4 1.3 6.6 2.2 0.9 11.5 1.6 2.8 3.9 0.4 0.6 24.9 3.3 10.5 0.6 15.4 0.3 4.6 0.2 76.4 28.5 8.4 6.8 10.0 3.6 11.0 0.4 2.1 12.5 19.1 19.0 9.3 1.1 1.3 0.5 7.9 0.2 3.8 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.1 0.0 0.0 127.9 131.0 122.0 147.7 166.8 120.6 154.9 130.9 142.6 124.6 139.3 164.4 1.7 6.4 4.1 7.2 0.9 2.4 5.8 2.0 2.8 34.4 6.1 5.3 1.1 5.7 3.3 11.0 22.9 1.6 0.4 2.2 13.7 6.9 43.8 23.9 15.9 2.9 40.2 0.0 10.3 28.9 0.6 6.5 4.1 19.9 0.0 2.8 0.4 4.6 0.5 67.3 11.6 1.6 4.1 0.8 3.5 39.2 6.2 1.1 3.6 1.0 1.6 41.3 0.0 3.5 48.7 11.6 0.5 6.4 0.1 6.3 1.4 8.9 10.9 18.3 0.0 14.2 6.0 10.6 8.2 0.9 1.0 5.7 1.3 7.7 0.9 5.5 MAT2B "MATIIbeta, SDR23E1" ENSG00000038274 "Methionine adenosyltransferase 2B" Q9NZL9 5 163503114-163519354 "Metabolic proteins, Predicted intracellular proteins" "One-carbon metabolism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037721, HPA037722" Uncertain Approved "Plasma membrane" NA NA 1100000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA037721: AB_10672389, HPA037722: AB_10671718" "unprognostic (1.22e-2)" "unprognostic (2.80e-2)" "unprognostic (1.80e-3)" "unprognostic (1.64e-1)" "unprognostic (5.06e-1)" "unprognostic (2.12e-1)" "unprognostic (1.20e-1)" "unprognostic (1.77e-1)" "unprognostic (9.72e-2)" "unprognostic (1.68e-1)" "unprognostic (5.19e-3)" "unprognostic (3.57e-2)" "prognostic favorable (4.51e-7)" "unprognostic (1.06e-1)" "unprognostic (1.09e-2)" "unprognostic (2.16e-2)" "unprognostic (1.37e-3)" 36.6 54.6 31.1 64.7 32.4 31.1 50.5 35.3 39.8 46.9 37.5 61.5 86.9 45.4 59.4 40.9 66.7 42.1 75.3 32.8 33.7 104.8 82.7 56.1 102.6 32.2 35.3 73.3 23.9 69.2 22.0 48.9 33.3 46.1 66.5 47.8 64.3 53.2 57.8 34.6 84.4 44.4 34.6 84.5 57.2 31.7 33.3 89.6 81.4 63.7 92.7 60.9 33.2 34.0 72.4 60.0 100.6 55.1 73.4 72.9 62.2 61.8 68.5 67.7 99.4 41.5 128.5 74.8 127.6 66.0 99.5 56.6 84.8 125.4 89.1 254.5 69.6 67.3 63.3 62.1 95.9 71.0 44.7 60.4 101.1 86.1 66.4 81.8 149.5 76.6 54.8 90.8 84.0 40.7 99.2 85.9 38.6 43.9 40.0 112.4 49.2 123.4 111.7 76.6 40.4 57.9 82.8 58.2 93.8 44.1 76.5 95.1 121.2 73.6 48.5 51.8 107.7 78.4 82.3 68.3 54.1 129.1 51.3 619.4 227.5 477.4 321.5 274.3 355.8 359.1 351.2 349.3 204.6 345.3 352.7 341.4 357.8 401.5 302.4 167.2 528.3 689.9 31.1 32.4 35.3 39.8 32.8 33.7 32.2 35.3 33.3 34.6 33.3 34.0 24.9 48.1 43.3 8.8 90.1 42.7 35.1 75.6 129.1 23.2 26.0 20.7 57.7 41.5 48.1 44.1 8.4 61.3 62.8 49.2 62.6 38.8 39.0 63.5 36.2 38.9 15.0 79.3 15.0 26.2 29.7 34.6 36.2 44.2 28.4 28.1 35.7 58.3 45.3 18.5 12.8 40.8 61.1 83.3 55.3 13.3 34.5 48.5 42.7 18.7 70.6 41.7 80.3 9.0 16.2 28.9 38.1 31.2 65.7 46.8 53.4 103.7 72.6 17.6 46.0 21.7 35.6 23.6 30.5 69.8 36.2 37.6 84.2 23.3 51.3 45.7 MBP ENSG00000197971 "Myelin basic protein" P02686 18 76978827-77133683 "Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Autoimmune encephalomyelitis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 142 "brain: 30812.9;choroid plexus: 9144.9" "Cell type enriched" "Detected in many" 11 "Oligodendrocytes: 2895.5" "Group enriched" "Detected in all" 9 "glioma: 47.5;melanoma: 20.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HL-60: 99.3;SK-MEL-30: 204.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002300, HPA049222, HPA064368" Enhanced Supported Approved "Plasma membrane" NA NA 54000 "Cluster 5: Granulocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "CAB002300: AB_563893, HPA049222: AB_2680679, HPA064368: AB_2685247" "unprognostic (9.36e-2)" "unprognostic (7.60e-2)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" "unprognostic (6.93e-2)" "unprognostic (2.81e-1)" "unprognostic (1.14e-1)" "unprognostic (3.31e-1)" "unprognostic (9.87e-2)" "unprognostic (2.90e-2)" "unprognostic (5.25e-2)" "unprognostic (1.95e-1)" "prognostic favorable (4.48e-12)" "unprognostic (2.90e-1)" "unprognostic (5.99e-2)" "unprognostic (1.33e-1)" "unprognostic (6.03e-2)" 27.3 7.1 15448.6 20.9 21296.6 43.0 20.9 19749.8 26916.8 17.3 9144.9 19.0 18.6 13.2 7.9 20.5 31.5 17.2 24.1 12696.6 16271.8 28.7 23.5 20.0 26.9 30812.9 22193.8 22.3 22.8 47.5 26.7 4.7 25986.2 15.3 16.9 7.5 22.0 13.0 140.8 28.7 20.7 8.7 23219.4 28.0 17.5 6.1 19406.0 12.5 22.2 81.6 27.8 19.0 20.2 30044.2 26.1 22.4 0.2 0.8 35.8 53.1 8.5 0.6 0.6 0.8 0.6 3.2 39.2 15.9 4.4 1.7 0.2 49.9 3.8 22.1 0.7 60.7 5.3 10.4 3.9 5.2 22.5 99.3 65.3 7.7 18.4 19.8 30.3 16.4 6.5 37.9 0.0 3.6 0.0 3.2 4.1 50.6 2.2 15.6 18.1 1.5 0.4 35.9 34.5 34.3 1.8 0.3 3.2 0.0 204.7 6.1 0.6 60.5 0.1 0.2 0.5 0.2 2.8 0.1 0.5 16.9 5.8 62.0 2.5 21.7 8.5 32.4 21.6 8.1 13.1 5.9 15.4 28.1 9.2 5.1 9.1 17.0 39.5 28.0 8.1 11.9 14.9 11.6 15448.6 21296.6 19749.8 26916.8 12696.6 16271.8 30812.9 22193.8 25986.2 23219.4 19406.0 30044.2 5.5 48.1 39.5 10.7 86.8 118.8 61.1 28.1 84.2 52.8 24.2 22.7 45.0 35.8 50.3 103.0 2.1 0.7 221.8 48.7 41.1 43.7 5.9 159.8 11.2 9.4 49.8 68.8 32.4 35.8 0.8 36.2 59.1 161.1 71.5 2.1 10.0 30.2 44.4 1.7 47.1 51.4 44.7 78.3 123.1 6.3 28.3 98.2 92.5 45.0 84.4 25.7 247.2 124.7 2895.5 60.4 25.5 14.3 45.3 117.6 37.5 36.0 54.0 6.1 0.0 88.7 8.4 7.7 1.1 75.6 154.7 0.7 151.6 0.0 42.1 103.7 MC5R ENSG00000176136 "Melanocortin 5 receptor" P33032 18 13824149-13827323 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 2.4;lymphoid tissue: 1.0" "Cell type enriched" "Detected in single" 17 "Squamous epithelial cells: 1.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "U-138 MG: 1.8" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA042365, HPA058088" Approved Supported "Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA042365: AB_2677961, HPA058088: " "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" "unprognostic (8.77e-2)" "unprognostic (7.10e-2)" "unprognostic (2.64e-2)" "unprognostic (1.30e-2)" "unprognostic (9.04e-3)" "unprognostic (1.54e-1)" 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 2.4 0.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.3 1.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 MCAM "CD146, HEMCAM, MelCAM, METCAM, MUC18" ENSG00000076706 "Melanoma cell adhesion molecule" P43121 11 119308529-119321521 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 128.5;Endothelial cells: 153.5;Muller glia cells: 89.8;Sertoli cells: 322.1;Smooth muscle cells: 384.6" "Cancer enhanced" "Detected in all" "melanoma: 83.8" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "HUVEC TERT2: 1121.0;TIME: 1107.4;WM-115: 869.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002147, HPA008848" Enhanced Approved "Plasma membrane" NA NA 1900000000 "Cluster 13: T-cells - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" "CAB002147: AB_563499, HPA008848: AB_1078445" "unprognostic (6.45e-2)" "prognostic unfavorable (7.61e-4)" "unprognostic (7.03e-2)" "unprognostic (1.22e-2)" "unprognostic (6.67e-2)" "unprognostic (2.34e-1)" "unprognostic (2.23e-2)" "unprognostic (8.42e-2)" "unprognostic (2.09e-2)" "unprognostic (1.45e-1)" "unprognostic (1.58e-1)" "unprognostic (9.39e-2)" "prognostic unfavorable (5.14e-4)" "unprognostic (8.75e-3)" "unprognostic (7.84e-2)" "unprognostic (2.31e-1)" "unprognostic (2.79e-3)" 332.7 30.0 36.6 68.4 46.1 1.2 180.6 45.7 45.3 96.6 25.3 166.3 29.2 175.8 47.0 89.2 136.4 66.8 118.0 35.3 44.7 42.0 10.5 116.4 19.6 59.4 43.1 60.9 22.0 93.9 17.8 168.0 52.2 78.1 32.2 12.2 39.5 148.0 40.7 50.9 73.0 160.9 36.2 35.4 97.7 9.7 50.2 15.5 58.7 37.4 15.4 174.5 79.8 44.8 0.7 5.1 4.7 0.3 21.5 0.3 23.2 3.2 0.3 29.9 13.3 17.9 0.9 1.2 94.5 10.7 44.7 3.2 38.3 8.1 15.0 56.9 14.5 1.2 102.4 19.8 51.0 0.1 0.4 15.2 0.3 40.8 18.7 1.1 1121.0 7.1 38.7 1.5 6.1 0.0 1.2 9.3 19.9 0.2 4.4 0.9 147.8 32.9 27.1 0.0 12.5 3.9 87.1 2.1 249.2 46.2 4.3 0.9 1107.4 3.1 156.7 0.2 89.1 2.4 2.3 0.6 43.1 0.1 869.3 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 36.6 46.1 45.7 45.3 35.3 44.7 59.4 43.1 52.2 36.2 50.2 44.8 128.5 0.0 2.3 1.3 1.4 4.7 0.6 11.1 8.0 1.2 9.9 19.7 65.8 18.6 1.1 0.0 22.9 0.5 2.5 0.1 0.0 17.3 1.7 7.8 14.0 153.5 0.0 0.0 1.4 0.4 38.7 14.1 1.5 10.3 0.0 18.2 60.0 0.6 0.8 0.0 3.5 0.0 0.0 1.3 7.0 0.7 0.9 2.4 21.4 14.0 0.6 89.8 1.0 18.6 45.2 1.6 0.0 25.2 3.1 1.7 0.0 0.9 1.3 4.0 322.1 9.9 384.6 2.1 1.6 1.7 3.3 0.4 9.3 4.9 0.1 1.8 MCEMP1 "C19orf59, MGC132456" ENSG00000183019 "Mast cell expressed membrane protein 1" Q8IX19 19 7676628-7679826 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 11 "bone marrow: 65.9;lung: 74.2;lymphoid tissue: 35.1" "Cell type enriched" "Detected in some" 4 "Macrophages: 147.5" "Cancer enhanced" "Detected in many" "lung cancer: 3.7" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Group enriched" "Detected in some" 5 "classical monocyte: 102.1;neutrophil: 45.9" "Group enriched" "Detected in many" 5 "granulocytes: 45.9;monocytes: 102.1" "Group enriched" "Detected in some" 6 "THP-1: 53.7;U-937: 166.6" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Not detected" "Not detected" HPA014731 Enhanced Supported "Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA014731: AB_1845619" "unprognostic (4.84e-2)" "unprognostic (9.81e-4)" "unprognostic (2.41e-1)" "unprognostic (4.36e-2)" "unprognostic (8.85e-3)" "unprognostic (2.62e-3)" "unprognostic (5.57e-3)" "unprognostic (1.42e-1)" "unprognostic (2.19e-1)" "unprognostic (4.36e-2)" "unprognostic (1.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.69e-5)" "unprognostic (1.15e-2)" "unprognostic (7.37e-2)" "unprognostic (1.93e-2)" "unprognostic (7.95e-2)" 4.0 0.5 0.0 19.7 0.0 65.9 0.5 0.0 2.1 0.1 0.0 0.4 0.2 0.1 0.0 0.5 1.7 0.6 1.3 0.0 0.0 0.7 1.5 74.2 0.1 0.0 0.0 0.2 0.7 0.0 0.2 1.8 0.9 0.5 0.1 0.0 0.8 0.0 0.3 0.1 0.6 5.1 0.0 35.1 0.9 0.2 0.7 0.9 0.4 1.5 0.1 4.7 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 8.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 1.4 17.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 53.7 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 166.6 0.0 0.0 102.1 2.8 0.2 6.0 0.0 0.0 0.3 0.0 14.9 0.0 0.0 0.3 45.9 0.6 0.4 0.9 0.2 38.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.9 0.0 0.7 0.0 0.4 19.2 34.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.5 11.2 0.0 0.0 0.2 0.3 0.1 0.0 0.0 0.1 0.0 0.0 2.2 0.0 3.6 0.0 0.0 1.0 2.9 0.0 0.0 7.6 0.0 0.0 0.3 28.8 0.0 0.0 0.0 0.0 28.3 0.0 0.1 0.0 147.5 0.0 0.0 26.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.2 5.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.8 2.9 0.0 0.0 0.1 MMP25 "MMP20, MMPL1, MT6-MMP" ENSG00000008516 "Matrix metallopeptidase 25" Q9NPA2 16 3046062-3060726 "Enzymes, Predicted secreted proteins" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 33.1;lymphoid tissue: 81.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 6.7;Langerhans cells: 5.8;monocytes: 15.0" "Cancer enriched" "Detected in many" 5 "testis cancer: 7.1" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "basophil: 18.3;neutrophil: 20.3" "Lineage enriched" "Detected in single" 39 "granulocytes: 20.3" "Cell line enriched" "Detected in some" 15 "HMC-1: 102.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB025177, HPA055640" Uncertain Supported "Plasma membrane" "Secreted to blood" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "CAB025177: , HPA055640: " "unprognostic (4.51e-3)" "unprognostic (9.28e-3)" "unprognostic (7.57e-2)" "unprognostic (2.95e-3)" "unprognostic (2.26e-1)" "prognostic favorable (1.09e-5)" "unprognostic (1.36e-1)" "unprognostic (7.39e-3)" "unprognostic (7.63e-3)" "unprognostic (2.29e-2)" "unprognostic (1.51e-1)" "unprognostic (2.53e-2)" "unprognostic (2.37e-3)" "unprognostic (1.17e-2)" "unprognostic (8.30e-2)" "unprognostic (4.01e-1)" "unprognostic (2.02e-1)" 5.8 0.4 0.5 15.1 0.4 33.1 1.4 0.3 1.6 0.7 0.6 1.7 1.1 0.5 0.1 1.3 6.2 1.1 2.4 0.3 0.3 1.4 2.9 14.4 2.6 0.6 0.5 0.4 1.2 0.2 0.8 1.0 0.6 1.0 1.4 0.0 1.2 0.1 0.5 0.7 3.5 0.9 0.3 81.8 1.9 0.4 0.7 1.4 1.2 3.5 1.9 2.2 0.9 0.3 0.0 0.0 1.2 2.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.7 0.7 0.1 0.0 6.7 0.5 0.0 0.0 0.0 0.0 0.2 102.2 0.1 0.1 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 5.7 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.3 7.0 0.3 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 1.1 0.1 18.3 0.2 4.0 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.0 20.3 0.5 0.0 0.4 0.2 0.0 0.5 0.4 0.3 1.6 0.3 0.3 0.6 0.5 0.6 0.3 0.7 0.3 1.0 3.2 6.7 0.0 0.7 0.4 0.4 0.2 0.0 0.8 2.0 1.3 1.0 0.0 0.8 1.8 0.0 0.0 1.8 0.2 0.0 0.4 0.0 1.2 1.2 1.0 0.0 2.7 1.6 0.6 0.2 0.6 1.1 3.8 1.3 0.2 0.0 0.3 0.1 0.0 1.9 0.2 0.0 3.5 5.8 0.0 0.0 3.3 0.0 1.0 15.0 0.3 3.1 1.5 0.5 1.3 0.0 0.7 0.8 0.4 1.2 0.2 0.1 0.0 0.0 0.7 0.9 0.1 0.2 0.6 0.3 0.0 4.0 0.1 0.3 0.3 MR1 HLALS ENSG00000153029 "Major histocompatibility complex, class I-related" Q95460 1 181033425-181061938 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA048304 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 34: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA048304: AB_2680347" "unprognostic (6.89e-2)" "unprognostic (1.54e-1)" "unprognostic (1.31e-2)" "unprognostic (1.96e-1)" "unprognostic (8.66e-3)" "unprognostic (4.37e-2)" "unprognostic (1.96e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.18e-1)" "unprognostic (3.49e-2)" "unprognostic (6.41e-2)" "unprognostic (1.05e-2)" "unprognostic (7.40e-3)" "unprognostic (4.69e-2)" "unprognostic (2.39e-1)" "unprognostic (1.07e-2)" 8.6 9.6 3.2 14.2 3.3 11.1 9.7 2.2 3.5 10.2 5.8 6.7 7.4 9.5 9.6 9.6 10.4 12.7 6.2 3.1 3.8 9.9 10.6 18.0 14.6 4.7 3.3 13.6 3.7 14.0 8.9 13.5 3.7 10.9 8.1 1.5 5.9 10.5 2.1 8.7 6.9 12.5 3.8 12.3 8.7 2.6 4.4 20.2 16.7 3.8 15.2 16.3 7.4 4.8 7.9 5.4 0.1 4.6 32.2 38.8 13.9 15.5 42.2 12.7 21.5 2.2 31.9 9.7 31.6 28.1 9.9 20.5 0.7 18.3 11.1 29.6 5.2 14.2 5.6 9.8 10.8 11.5 40.6 25.2 49.6 18.9 20.3 23.7 1.3 17.8 26.7 25.6 24.9 8.8 12.1 8.3 0.1 0.1 0.8 13.7 0.3 27.3 13.9 23.1 0.2 0.3 8.2 14.8 10.9 6.0 15.4 24.6 8.1 12.5 1.7 21.8 7.7 42.2 15.3 17.9 11.7 14.7 1.2 32.6 21.8 22.9 16.3 27.4 14.6 14.3 14.6 14.6 18.8 18.3 10.8 16.2 14.7 19.0 23.6 10.2 17.0 15.2 3.2 3.3 2.2 3.5 3.1 3.8 4.7 3.3 3.7 3.8 4.4 4.8 4.4 19.2 32.4 8.8 14.7 5.0 8.3 32.6 12.0 0.8 7.7 6.1 4.1 8.6 20.9 14.7 0.0 17.5 15.9 1.6 5.9 10.8 0.3 5.9 12.1 4.9 2.4 11.4 3.1 6.4 9.5 12.8 2.6 7.3 17.1 13.5 3.6 8.9 25.8 0.0 1.7 2.7 32.6 25.2 9.1 0.4 10.8 25.3 7.2 11.2 30.8 4.1 26.8 0.0 0.5 7.5 4.5 12.0 9.1 7.4 2.2 2.4 15.3 0.6 0.0 8.6 9.2 0.4 1.6 10.9 5.4 24.5 15.7 22.4 3.5 13.4 MS4A1 "B1, Bp35, CD20, MS4A2" ENSG00000156738 "Membrane spanning 4-domains A1" P11836 11 60455846-60470752 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "B-cell activation" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "lymphoid tissue: 673.3" "Cell type enriched" "Detected in some" 35 "B-cells: 970.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 96 "memory B-cell: 625.4;naive B-cell: 627.0" "Lineage enriched" "Detected in many" 96 "B-cells: 627.0" "Group enriched" "Detected in some" 26 "Daudi: 731.3;U-698: 364.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB000015, HPA014341, HPA014391" Enhanced Supported "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "CAB000015: AB_2282030, HPA014341: AB_1846265, HPA014391: AB_1846264" "prognostic favorable (4.34e-5)" "unprognostic (4.45e-4)" "unprognostic (1.19e-4)" "unprognostic (2.04e-3)" "unprognostic (1.06e-1)" "unprognostic (5.53e-7)" "unprognostic (2.46e-3)" "unprognostic (1.85e-3)" "unprognostic (3.06e-2)" "unprognostic (2.89e-4)" "unprognostic (6.96e-2)" "unprognostic (2.84e-2)" "unprognostic (3.96e-5)" "unprognostic (2.23e-1)" "unprognostic (8.04e-2)" "unprognostic (1.44e-1)" "unprognostic (1.30e-1)" 3.6 0.4 0.0 149.7 0.0 19.1 0.8 0.0 0.1 0.5 0.1 9.0 3.0 2.2 1.0 4.2 0.5 8.4 1.8 0.0 0.1 3.4 2.1 4.0 500.4 0.2 0.0 0.3 0.2 7.3 0.3 0.9 0.1 5.1 10.6 0.0 8.9 0.3 0.8 0.1 123.5 1.2 0.1 253.8 18.4 1.2 0.1 50.6 6.7 0.1 673.3 16.3 1.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 731.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.3 0.5 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.4 0.0 0.5 0.2 0.0 0.1 0.0 364.1 0.0 0.2 0.0 0.8 0.5 0.3 2.4 0.1 3.7 625.4 2.8 5.5 0.5 627.0 0.5 2.1 2.0 6.5 0.6 0.5 0.8 32.1 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.1 0.1 0.1 0.1 0.3 0.0 3.8 0.0 970.5 0.1 0.1 0.0 0.0 0.0 0.4 0.3 0.4 0.0 0.0 0.0 0.0 0.0 14.5 0.3 0.0 0.0 4.5 0.7 0.1 0.3 0.0 7.0 0.0 0.0 0.1 1.8 2.0 0.1 2.5 0.0 1.1 0.3 0.1 0.0 0.0 0.2 0.0 0.6 0.3 2.0 0.0 4.6 7.2 0.0 2.5 0.0 2.1 0.0 0.0 0.0 0.3 0.0 9.1 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.5 0.2 0.1 0.8 0.1 0.0 27.3 0.7 0.2 0.0 MSN ENSG00000147065 Moesin P26038 X 65588377-65741931 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "NK-cells: 337.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, CAB010898, HPA011135, HPA011227, CAB047336, CAB047337, CAB047338" Enhanced Enhanced "Plasma membrane" NA NA 130000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010898: AB_260635, CAB047336: , CAB047337: , CAB047338: , HPA000263: AB_1856043, HPA011135: AB_1854053, HPA011227: AB_1854054" "unprognostic (1.03e-1)" "unprognostic (7.89e-2)" "unprognostic (7.64e-2)" "unprognostic (5.38e-2)" "unprognostic (4.08e-3)" "unprognostic (3.51e-2)" "unprognostic (1.11e-2)" "unprognostic (1.44e-2)" "unprognostic (3.35e-2)" "unprognostic (1.70e-2)" "unprognostic (9.04e-3)" "unprognostic (1.32e-1)" "prognostic unfavorable (1.60e-5)" "unprognostic (5.68e-3)" "unprognostic (7.75e-2)" "unprognostic (7.21e-2)" "unprognostic (6.81e-2)" 213.3 83.3 66.6 259.8 71.4 269.8 144.6 80.0 70.9 113.9 79.6 116.0 43.9 155.8 45.0 87.9 110.0 123.1 130.2 64.8 95.9 139.7 91.8 281.5 207.5 101.9 79.6 91.9 41.0 39.2 48.2 150.6 98.8 72.5 78.4 24.0 76.0 126.6 56.2 100.7 96.6 251.6 91.8 200.0 78.4 21.9 87.3 177.0 152.5 75.7 242.2 154.8 98.0 95.5 298.3 223.2 214.0 177.9 250.6 328.9 1.9 733.9 472.2 397.3 305.5 0.6 50.9 247.7 638.8 654.4 210.3 199.4 228.5 523.4 514.1 461.7 63.0 687.5 355.0 0.6 236.0 845.3 1063.8 248.1 110.7 733.1 641.5 384.2 892.3 338.5 339.5 747.1 638.4 0.6 503.0 631.0 266.1 0.3 418.9 259.8 384.0 189.0 426.5 0.2 1.7 0.8 590.6 4.4 231.5 239.7 2.7 453.8 1426.9 449.5 285.3 613.2 494.6 268.6 438.4 262.5 328.9 1053.3 513.0 219.9 312.4 194.0 214.8 359.3 160.4 91.9 116.9 170.6 225.3 76.9 78.3 121.9 334.3 177.5 460.3 31.9 97.0 673.8 66.6 71.4 80.0 70.9 64.8 95.9 101.9 79.6 98.8 91.8 87.3 95.5 243.4 179.5 163.0 19.9 140.8 205.5 62.2 56.5 38.7 0.7 27.9 30.9 27.5 11.5 45.4 68.0 4.2 6.0 227.3 7.5 29.4 177.3 1.4 35.7 64.9 256.2 0.0 71.9 2.2 170.0 16.0 85.7 16.3 62.9 164.6 22.6 100.3 51.2 167.2 5.0 3.8 3.2 2.0 255.3 206.2 5.3 73.7 251.9 69.4 67.5 291.9 43.6 337.8 7.1 14.7 327.7 3.3 109.4 105.7 102.2 0.0 113.6 25.6 2.4 72.3 85.0 131.0 1.9 3.6 24.3 149.5 4.2 206.9 24.4 2.2 54.0 MTM1 ENSG00000171100 "Myotubularin 1" Q13496 X 150568621-150673143 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid metabolism, Protein transport, Transport" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 52.2;Oligodendrocytes: 47.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010008, HPA010665" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 43: THP-1 - Innate immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA010008: AB_1079426, HPA010665: AB_1079425" "unprognostic (3.66e-3)" "unprognostic (8.43e-3)" "unprognostic (3.52e-3)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (6.45e-2)" "unprognostic (4.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.74e-1)" "unprognostic (2.35e-2)" "unprognostic (1.08e-1)" "unprognostic (4.59e-2)" "prognostic favorable (7.40e-7)" "unprognostic (4.46e-2)" "unprognostic (1.25e-1)" "unprognostic (4.99e-2)" "unprognostic (2.46e-1)" 6.8 11.1 7.4 9.7 8.3 11.3 7.6 8.0 8.4 5.7 6.1 19.8 11.7 6.5 8.4 7.5 9.6 7.1 7.3 6.9 8.5 12.9 18.4 11.2 12.4 7.8 8.6 11.7 4.9 16.0 3.8 6.3 8.0 8.0 19.2 5.4 6.3 10.7 11.8 8.2 12.1 6.9 7.7 11.9 7.8 11.5 8.8 8.4 11.2 10.1 9.7 7.1 4.7 8.8 14.3 6.1 8.5 3.1 7.5 7.3 5.4 6.1 8.5 7.0 7.9 4.7 7.3 22.2 11.4 8.3 21.9 9.9 6.1 11.5 8.6 6.4 5.2 5.6 5.4 15.0 5.8 25.2 19.1 4.5 14.3 5.7 11.9 6.9 9.4 9.3 3.9 19.8 8.8 4.5 6.9 25.2 4.3 13.4 7.4 8.0 4.9 4.5 11.7 6.9 2.2 2.4 5.5 11.3 8.5 11.9 4.1 35.2 8.2 5.0 3.1 12.4 7.1 4.2 10.0 20.3 6.0 14.8 8.0 34.8 9.5 27.9 2.0 10.8 6.8 8.0 9.6 7.3 12.0 10.6 9.0 5.4 11.6 14.6 9.8 7.4 12.2 7.1 7.4 8.3 8.0 8.4 6.9 8.5 7.8 8.6 8.0 7.7 8.8 8.8 9.9 9.6 20.0 52.2 13.9 15.2 8.3 5.8 2.2 0.0 5.8 3.9 15.0 4.3 6.0 3.7 0.0 2.1 8.4 33.0 1.9 3.4 35.6 7.7 5.0 11.5 9.6 7.4 44.0 4.3 2.8 6.6 8.2 4.8 8.8 3.3 16.4 13.2 8.0 0.0 41.5 17.7 2.0 16.3 10.4 18.8 6.2 13.0 5.4 24.4 12.0 0.0 0.0 27.6 47.7 4.7 9.5 12.8 8.0 6.8 11.2 14.7 13.4 0.0 0.0 5.2 6.9 5.1 4.1 4.9 19.0 7.3 12.8 4.8 13.8 9.7 MUC1 "ADMCKD, ADMCKD1, CD227, MCD, MCKD, MCKD1, PEM, PUM" ENSG00000185499 "Mucin 1, cell surface associated" P15941 1 155185824-155192916 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 485.8;stomach 1: 1064.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 1370.0;Collecting duct cells: 491.1;Exocrine glandular cells: 1164.9;Gastric mucus-secreting cells: 640.6;Pancreatic endocrine cells: 1074.8;Respiratory ciliated cells: 555.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "T-reg: 1.2" "Lineage enhanced" "Detected in single" "T-cells: 1.2" "Group enriched" "Detected in many" 6 "CAPAN-2: 1146.1;OE19: 548.3;RPTEC TERT1: 870.2;T-47d: 383.6" "Not detected" "Not detected" "CAB000036, CAB001986, HPA004179, HPA007235, HPA008855" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA 4000000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB000036: AB_2148557, CAB001986: , HPA004179: AB_1846282, HPA007235: AB_1846281, HPA008855: AB_1846283" "unprognostic (4.74e-2)" "unprognostic (2.84e-2)" "unprognostic (2.19e-1)" "unprognostic (8.01e-2)" "unprognostic (1.32e-2)" "unprognostic (1.70e-1)" "unprognostic (2.61e-3)" "unprognostic (6.34e-2)" "unprognostic (1.43e-1)" "unprognostic (3.23e-1)" "prognostic unfavorable (4.60e-4)" "unprognostic (4.75e-1)" "unprognostic (2.05e-2)" "unprognostic (1.13e-1)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (1.21e-1)" 15.2 6.3 5.3 21.9 5.7 9.4 78.2 4.7 8.6 194.2 4.7 176.0 21.4 40.2 61.6 209.9 120.0 125.8 6.8 5.1 5.7 485.8 3.9 321.5 1.8 7.8 6.3 9.8 358.5 1.0 14.1 3.3 6.0 43.9 103.6 1.3 135.0 34.4 1.9 20.6 35.2 20.0 6.1 5.4 1064.7 47.9 6.8 1.2 54.8 0.7 18.8 102.0 50.0 5.2 15.3 8.2 5.1 4.8 3.9 4.2 1.7 5.6 12.2 6.2 15.2 0.2 1146.1 0.0 81.9 9.5 2.7 23.2 1.0 0.3 1.8 10.4 0.8 1.8 101.5 0.0 2.4 0.4 36.1 9.5 2.1 2.8 2.2 12.7 2.1 1.9 9.2 15.4 4.3 120.0 1.6 1.2 3.5 548.3 2.1 2.3 0.6 29.3 870.2 0.9 5.1 2.1 28.0 48.3 1.5 4.1 383.6 5.6 2.2 3.9 6.7 10.5 1.2 17.7 9.8 0.2 5.9 1.1 1.4 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 1.2 0.1 5.3 5.7 4.7 8.6 5.1 5.7 7.8 6.3 6.0 6.1 6.8 5.2 2.3 432.7 1370.0 5.9 6.4 0.6 18.5 126.4 0.0 1.3 219.2 48.5 0.4 327.5 374.9 491.1 4.2 0.5 1.5 271.8 35.2 177.3 32.7 245.2 28.8 8.0 30.6 1.3 0.3 1164.9 1.1 7.0 640.6 282.8 48.0 0.3 1.8 0.9 0.2 1.7 0.3 351.5 164.8 2.2 1.0 81.0 2.5 7.2 5.4 1.0 24.3 1.7 0.0 0.5 0.1 1074.8 60.5 1.5 1.3 16.3 6.8 1.3 555.3 0.2 0.0 2.0 22.0 5.8 0.8 3.5 1.1 0.3 10.3 0.1 220.8 154.5 MYL4 "ALC1, AMLC, GT1, PRO1957" ENSG00000198336 "Myosin light chain 4" P12829 17 47200446-47223679 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Motor protein, Muscle protein, Myosin" "Atrial fibrillation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 47 "heart muscle: 6347.0" "Cell type enriched" "Detected in many" 5 "Cardiomyocytes: 2426.3" "Cancer enriched" "Detected in some" 5 "thyroid cancer: 11.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 9 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 9 "dendritic cells: 1.8" "Cell line enriched" "Detected in some" 4 "HEL: 552.8" "Group enriched" "Detected in all" 6 "amygdala: 25.8;cerebral cortex: 88.4;hippocampal formation: 25.2;white matter: 50.9" "Not detected" "Not detected" "HPA046859, HPA051884, HPA063034" Enhanced Approved "Plasma membrane" NA NA 3100000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 36: HEL - Hemostasis" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA046859: AB_2679842, HPA051884: AB_2681651, HPA063034: AB_2684927" "unprognostic (2.43e-2)" "unprognostic (9.57e-2)" "unprognostic (2.25e-1)" "unprognostic (5.51e-2)" "unprognostic (2.33e-1)" "unprognostic (4.12e-3)" "unprognostic (5.06e-3)" "unprognostic (1.34e-1)" "unprognostic (1.13e-1)" "unprognostic (6.52e-2)" "unprognostic (2.10e-2)" "unprognostic (7.37e-2)" "unprognostic (1.00e-6)" "unprognostic (1.92e-4)" "unprognostic (2.54e-1)" "unprognostic (6.51e-3)" "unprognostic (1.50e-1)" 2.1 0.5 0.2 0.4 0.3 134.6 2.7 0.2 0.4 0.4 0.4 0.8 0.8 0.8 0.0 0.6 0.5 1.0 6347.0 0.3 0.4 1.3 1.4 9.4 0.9 0.3 0.3 0.8 8.6 0.3 0.5 9.1 0.4 1.1 0.3 42.2 3.0 0.2 3.5 1.2 1.3 0.8 0.2 3.1 3.4 15.5 0.3 2.4 11.0 6.4 0.4 0.9 0.8 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.9 0.3 0.0 0.2 0.0 0.9 0.1 1.6 0.9 0.0 0.4 0.0 0.1 0.0 0.0 3.0 0.2 552.8 0.1 0.0 0.0 0.0 0.3 21.2 0.0 0.3 0.1 0.0 1.0 1.4 133.3 0.3 0.2 0.0 10.0 0.1 0.3 0.0 0.4 0.3 12.9 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 24.3 0.0 0.2 4.5 0.0 0.3 0.1 0.0 0.3 0.0 13.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.2 0.2 0.3 0.2 0.4 0.3 0.4 0.3 0.3 0.4 0.2 0.3 0.4 3.2 3.2 0.0 0.0 0.7 0.8 0.0 0.0 0.0 5.5 0.0 0.0 2426.3 0.0 0.0 0.0 64.6 0.5 2.7 0.1 0.0 0.1 23.3 0.1 0.0 23.2 0.0 412.8 0.1 0.0 3.9 150.7 1.5 0.1 0.0 0.3 1.8 0.5 1.9 1.7 0.0 0.8 0.0 0.6 0.6 54.6 3.4 34.0 12.4 0.0 1.5 7.9 4.1 0.0 0.1 0.1 0.0 1.5 0.8 0.0 10.9 0.2 0.0 24.4 0.0 0.6 36.5 9.9 0.5 0.0 0.9 1.4 0.3 0.2 1.0 0.0 MYO1B myr1 ENSG00000128641 "Myosin IB" O43795 2 191245185-191425389 "Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 255.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 330.2;Hepatocytes: 414.2;Sertoli cells: 203.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 360.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013607, HPA060144" Approved Enhanced "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA013607: AB_1854251, HPA060144: AB_2684211" "unprognostic (4.11e-3)" "unprognostic (7.36e-3)" "unprognostic (1.21e-1)" "unprognostic (4.83e-3)" "unprognostic (2.78e-1)" "unprognostic (1.59e-3)" "unprognostic (1.09e-2)" "unprognostic (1.15e-2)" "unprognostic (3.25e-3)" "unprognostic (5.85e-2)" "unprognostic (4.55e-1)" "unprognostic (9.31e-2)" "prognostic unfavorable (2.36e-5)" "unprognostic (2.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" 42.9 7.3 9.2 15.4 7.8 0.6 27.4 3.5 11.4 13.3 5.8 23.7 13.2 16.2 16.6 15.9 9.2 26.7 19.1 7.1 5.3 25.6 255.5 74.9 11.3 4.2 8.9 14.0 49.3 34.6 5.8 48.4 6.0 15.1 22.0 21.5 12.8 17.7 9.2 15.3 13.4 20.1 3.9 8.2 12.2 9.6 13.2 17.4 19.3 13.6 10.5 25.4 14.3 6.7 102.5 51.7 82.6 24.9 22.4 95.0 74.6 190.8 93.9 129.0 127.4 63.9 8.9 0.1 31.0 220.5 52.1 221.0 27.4 164.3 161.1 0.3 23.9 0.2 22.6 82.3 52.1 2.2 0.6 38.6 111.1 135.0 360.0 47.6 23.8 42.4 0.2 0.4 120.7 43.5 39.7 12.4 53.9 6.7 81.2 50.5 52.6 7.7 51.0 42.8 41.8 109.0 64.5 11.1 57.9 70.2 10.1 3.1 29.1 122.7 61.5 75.0 22.7 0.9 0.5 1.1 74.4 0.4 69.7 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.2 7.8 3.5 11.4 7.1 5.3 4.2 8.9 6.0 3.9 13.2 6.7 95.8 330.2 112.5 1.6 3.6 76.7 58.2 78.7 31.9 1.4 29.0 22.9 7.9 45.8 84.3 69.9 0.0 5.2 0.8 30.4 0.0 120.4 2.9 13.0 20.2 60.5 58.5 10.7 22.3 44.6 26.5 40.3 18.3 18.1 3.8 129.1 5.0 414.2 4.2 0.0 38.0 24.6 34.6 10.5 10.0 3.8 5.0 2.3 26.6 70.3 1.0 72.2 0.0 1.0 0.8 38.1 54.1 9.1 0.4 112.2 4.5 1.2 48.2 2.7 203.8 32.6 160.1 2.4 21.0 13.9 28.1 3.4 3.3 44.9 38.0 47.1 MYO5B KIAA1119 ENSG00000167306 "Myosin VB" Q9ULV0 18 49822789-50195147 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 62.0" "Cell type enhanced" "Detected in many" "Distal enterocytes: 147.3;Inhibitory neurons: 90.5;Pancreatic endocrine cells: 106.6;Proximal enterocytes: 177.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 65.5;HaCaT: 100.3;RH-30: 152.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA040593, HPA040902, HPA069773" Enhanced Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA040593: AB_10795525, HPA040902: AB_10796230, HPA069773: AB_2686194" "unprognostic (2.51e-1)" "unprognostic (2.15e-2)" "unprognostic (2.12e-2)" "unprognostic (6.17e-3)" "unprognostic (2.14e-1)" "unprognostic (8.84e-3)" "unprognostic (1.32e-1)" "unprognostic (2.59e-1)" "unprognostic (4.13e-2)" "unprognostic (3.46e-1)" "prognostic unfavorable (2.26e-5)" "unprognostic (4.48e-2)" "prognostic favorable (1.45e-11)" "unprognostic (2.17e-3)" "unprognostic (1.50e-1)" "unprognostic (6.56e-2)" "unprognostic (3.28e-1)" 3.2 1.7 1.0 7.9 3.3 0.1 13.7 0.5 3.6 17.7 15.9 45.3 60.2 2.6 18.5 37.4 12.2 11.3 2.7 4.4 10.4 19.7 18.7 11.9 2.6 0.5 3.4 0.5 16.6 23.0 13.4 3.8 1.6 10.1 43.6 40.9 25.4 7.1 0.4 27.4 62.0 3.1 0.4 1.7 33.3 11.4 1.9 3.1 29.4 0.2 13.0 14.2 21.6 1.4 65.5 17.3 0.3 0.3 0.0 0.0 34.0 0.3 2.6 1.4 0.1 45.8 27.2 0.1 15.6 0.1 5.0 100.3 22.6 27.3 1.3 0.2 6.9 0.2 7.5 32.8 0.0 0.2 0.2 0.0 23.6 0.6 16.2 5.1 2.3 0.3 0.5 24.7 2.7 25.3 0.0 0.2 4.6 37.8 7.0 0.0 152.5 11.0 56.8 13.2 33.7 0.7 24.4 28.3 0.0 8.6 16.8 0.2 1.5 0.0 34.0 0.4 6.8 16.7 11.2 0.1 1.4 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 1.0 3.3 0.5 3.6 4.4 10.4 0.5 3.4 1.6 0.4 1.9 1.4 0.1 54.5 15.8 2.6 1.6 0.4 9.0 7.9 2.2 7.7 14.3 7.7 3.5 15.7 21.5 7.3 10.4 4.4 0.3 147.3 5.9 49.0 22.4 38.5 3.1 1.1 6.7 5.3 4.4 47.3 1.1 3.7 48.4 29.1 0.0 27.1 0.0 18.4 0.9 0.0 90.5 35.4 2.0 1.3 0.8 4.5 0.9 1.0 3.6 3.7 2.0 31.9 0.0 2.0 9.0 106.6 70.7 0.7 1.4 60.1 177.6 18.9 38.1 30.2 0.0 0.9 2.3 9.5 6.7 8.3 6.5 4.7 0.7 0.1 46.7 56.2 MYO9A "FLJ11061, FLJ13244, MGC71859" ENSG00000066933 "Myosin IXA" B2RTY4 15 71822291-72118577 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, GTPase activation, Motor protein, Myosin" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 61.7" "Cell type enhanced" "Detected in all" "Excitatory neurons: 225.5;Inhibitory neurons: 192.9;Rod photoreceptor cells: 462.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039812, HPA040071" Approved Approved "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA039812: AB_10961421, HPA040071: AB_10961117" "unprognostic (7.53e-2)" "unprognostic (2.40e-1)" "unprognostic (1.96e-1)" "unprognostic (2.42e-3)" "unprognostic (1.63e-1)" "unprognostic (8.69e-3)" "unprognostic (3.77e-2)" "unprognostic (3.56e-2)" "unprognostic (1.26e-1)" "unprognostic (5.50e-2)" "unprognostic (1.32e-1)" "unprognostic (1.34e-1)" "prognostic favorable (2.14e-4)" "unprognostic (3.44e-1)" "unprognostic (4.41e-1)" "unprognostic (1.25e-1)" "unprognostic (4.23e-2)" 6.5 3.9 11.3 4.8 14.9 4.8 10.7 14.3 13.3 8.7 2.5 7.1 2.1 9.9 7.4 7.7 7.2 5.2 6.7 12.8 9.2 13.7 3.7 8.8 6.4 8.7 8.0 12.1 3.3 7.4 4.7 7.6 9.2 8.0 6.3 61.7 4.5 7.5 8.1 8.7 4.6 10.2 6.7 7.3 5.2 28.7 9.5 6.7 13.2 14.9 6.4 6.5 6.1 13.5 9.7 14.6 9.6 6.8 14.2 16.5 5.7 9.1 9.8 9.0 9.1 7.1 6.6 43.3 5.4 17.9 11.8 9.0 19.2 10.3 11.9 9.5 11.1 11.1 8.9 3.2 9.0 11.2 8.5 9.5 10.2 10.6 15.2 7.6 11.5 7.7 7.2 10.3 12.2 6.0 6.4 4.5 5.2 3.5 5.9 4.6 18.2 4.3 10.9 14.3 5.4 5.9 12.0 10.0 9.5 11.6 8.0 5.3 15.5 18.0 8.7 29.7 10.4 6.5 17.3 11.3 10.8 9.2 8.1 1.7 1.5 3.7 3.6 1.4 4.9 3.1 3.5 3.0 1.6 4.0 3.6 3.4 0.2 2.8 2.6 6.3 3.1 0.9 11.3 14.9 14.3 13.3 12.8 9.2 8.7 8.0 9.2 6.7 9.5 13.5 37.0 115.4 77.4 145.6 18.4 20.9 22.2 12.4 20.5 56.3 26.2 25.0 35.5 5.7 24.1 29.5 54.2 11.9 30.2 21.1 17.6 6.1 131.8 27.9 47.3 29.6 12.6 19.6 225.5 8.0 11.3 35.6 15.8 41.2 10.1 53.1 22.1 5.7 9.0 53.8 192.9 9.7 8.2 54.8 10.0 161.9 38.8 17.7 23.2 113.4 13.0 24.0 14.4 177.0 180.2 10.9 15.5 42.9 12.2 25.0 10.4 14.1 28.3 462.1 19.7 54.9 32.6 115.2 41.8 18.4 23.9 12.0 18.5 17.0 12.8 15.7 NAPG ENSG00000134265 "NSF attachment protein gamma" Q99747 18 10525905-10552764 "Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008208, HPA011389" Enhanced Approved "Plasma membrane" NA NA 8800 "Cluster 49: Eosinophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "HPA008208: AB_1854305, HPA011389: AB_1854306" "unprognostic (1.23e-1)" "unprognostic (7.64e-3)" "unprognostic (6.96e-2)" "unprognostic (1.53e-1)" "unprognostic (9.83e-2)" "unprognostic (2.28e-1)" "unprognostic (1.28e-1)" "unprognostic (4.59e-2)" "unprognostic (1.55e-2)" "unprognostic (2.77e-3)" "unprognostic (1.46e-3)" "unprognostic (5.85e-2)" "prognostic favorable (8.14e-4)" "unprognostic (3.81e-2)" "unprognostic (2.87e-1)" "unprognostic (4.97e-2)" "unprognostic (6.96e-2)" 11.3 14.8 18.4 9.7 18.6 7.2 11.8 21.1 25.3 10.5 13.9 11.9 9.3 10.7 12.0 12.1 11.0 13.4 19.9 25.9 20.8 16.4 13.6 9.7 9.6 30.3 20.1 7.5 12.6 12.4 9.9 13.9 32.6 13.7 13.7 12.6 11.7 10.7 10.2 9.9 10.7 11.8 19.4 9.4 13.7 7.4 20.1 9.0 14.5 14.6 11.2 14.3 10.1 21.7 9.4 5.6 9.6 8.3 27.1 18.4 14.0 19.8 28.1 19.0 24.0 12.4 14.1 12.3 15.5 27.3 17.4 9.0 12.7 17.7 26.9 11.0 7.8 9.2 9.8 12.8 25.9 26.0 16.6 20.3 20.6 21.8 16.2 12.4 18.0 16.0 15.1 29.0 28.2 13.2 20.0 11.1 7.7 72.3 8.3 8.7 15.8 21.2 22.5 22.0 38.3 10.1 16.1 16.9 23.1 15.5 7.7 17.2 20.5 29.8 14.4 27.8 21.2 18.8 20.4 13.6 20.1 17.7 14.2 12.5 4.9 14.1 5.1 6.1 4.7 7.5 4.1 5.2 3.8 3.3 5.6 4.8 8.1 5.8 6.1 4.1 4.4 3.1 18.4 18.6 21.1 25.3 25.9 20.8 30.3 20.1 32.6 19.4 20.1 21.7 32.2 28.9 34.7 33.6 29.1 24.3 31.1 26.9 21.6 62.0 21.8 17.4 35.1 21.5 27.5 27.6 12.5 23.6 32.9 30.8 41.1 53.3 18.1 27.9 33.2 23.4 23.4 33.2 68.5 42.5 30.3 25.3 28.5 49.5 45.0 13.6 20.0 21.7 25.4 45.4 53.8 22.3 28.5 22.1 16.1 4.6 7.8 24.5 26.6 30.9 22.4 31.3 22.6 34.7 52.9 77.7 34.1 21.1 36.2 34.8 20.8 39.5 20.8 34.0 26.3 30.5 29.6 26.6 39.9 30.8 21.2 45.1 26.2 28.4 19.0 56.5 NCKIPSD "AF3P21, DIP1, ORF1, SPIN90, WASLBP, WISH" ENSG00000213672 "NCK interacting protein with SH3 domain" Q9NZQ3 3 48673844-48686364 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "parathyroid gland: 121.9" "Cell type enhanced" "Detected in many" "Peritubular cells: 47.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB019267, HPA050005" Enhanced "Plasma membrane" NA NA 110000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 20: HeLa - Mitochondria" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "CAB019267: , HPA050005: AB_2680988" "unprognostic (1.55e-2)" "unprognostic (2.02e-1)" "unprognostic (2.15e-1)" "unprognostic (1.79e-1)" "unprognostic (9.64e-3)" "unprognostic (5.50e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (1.76e-1)" "unprognostic (1.38e-1)" "unprognostic (1.04e-1)" "unprognostic (2.40e-2)" "unprognostic (1.23e-1)" "prognostic favorable (1.20e-5)" "unprognostic (1.60e-2)" "unprognostic (1.55e-1)" "unprognostic (3.73e-2)" "unprognostic (2.09e-2)" 18.6 17.7 25.5 6.3 28.5 5.9 17.0 16.4 47.6 14.9 2.4 13.7 10.0 12.9 11.4 11.1 16.3 12.4 37.5 26.3 23.0 19.3 14.3 16.5 8.5 23.1 16.4 31.1 11.8 121.9 20.1 11.1 22.5 17.5 9.8 11.3 14.1 15.8 12.6 19.8 12.5 11.7 13.1 11.5 11.6 16.4 23.7 6.3 13.6 10.0 7.0 12.6 14.6 29.3 20.9 18.0 18.0 18.6 24.0 14.5 25.0 20.5 22.8 22.2 28.2 26.6 12.4 15.3 10.9 12.2 25.4 13.8 23.2 27.1 12.7 17.3 28.3 27.4 73.2 21.5 20.9 18.8 29.6 14.0 23.3 30.9 19.3 25.2 12.8 19.1 9.5 19.8 18.1 15.3 17.1 15.8 21.0 20.6 31.5 8.6 8.3 25.8 12.3 21.2 18.7 15.1 21.4 19.9 17.4 16.3 17.7 22.7 7.2 19.0 21.3 22.8 27.5 17.7 14.1 17.0 21.7 24.6 29.8 0.6 2.9 0.1 2.1 3.4 1.5 2.9 2.4 2.4 3.6 1.4 3.5 2.4 0.2 3.4 1.8 5.2 2.9 2.9 25.5 28.5 16.4 47.6 26.3 23.0 23.1 16.4 22.5 13.1 23.7 29.3 15.9 0.0 6.9 7.2 2.9 2.5 3.7 8.1 1.8 9.2 3.8 5.5 17.0 5.7 4.0 1.8 12.5 9.6 4.5 10.8 5.9 7.0 2.4 4.7 5.5 8.1 8.4 4.8 11.8 4.6 10.5 5.4 6.6 5.8 5.7 7.6 23.6 6.4 8.6 11.8 10.9 6.0 6.1 6.5 6.1 2.5 18.3 6.4 1.8 1.9 4.5 3.5 0.0 2.5 8.3 7.5 6.2 47.4 3.9 2.3 13.8 7.6 3.9 6.3 13.1 4.0 6.4 5.6 18.4 2.8 1.7 8.2 3.3 8.6 8.7 2.3 NCS1 "FREQ, NCS-1" ENSG00000107130 "Neuronal calcium sensor 1" P62166 9 130172404-130237303 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 272.0;intestine: 123.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 40.9;Horizontal cells: 112.7;Inhibitory neurons: 42.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018587, HPA019713" Enhanced Supported Enhanced "Plasma membrane" NA NA 10000 "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "CAB018587: AB_649907, HPA019713: AB_1854404" "prognostic unfavorable (5.40e-4)" "unprognostic (1.57e-1)" "unprognostic (4.64e-3)" "prognostic unfavorable (8.69e-4)" "unprognostic (1.29e-1)" "unprognostic (9.23e-2)" "prognostic unfavorable (1.11e-4)" "unprognostic (1.61e-3)" "unprognostic (4.27e-1)" "unprognostic (1.21e-2)" "unprognostic (8.45e-2)" "unprognostic (1.58e-1)" "unprognostic (3.71e-3)" "unprognostic (8.59e-2)" "unprognostic (1.69e-1)" "prognostic unfavorable (8.25e-4)" "unprognostic (1.65e-1)" 8.3 26.2 183.3 13.4 96.0 8.4 5.1 0.0 227.7 22.6 0.0 123.6 5.2 70.7 5.7 40.6 29.3 13.9 12.6 272.0 20.8 17.6 2.8 9.5 1.9 17.0 23.4 10.8 4.9 2.3 14.5 1.7 16.6 36.1 10.1 8.5 8.1 65.1 3.1 18.3 19.8 58.6 2.3 1.2 25.1 3.1 75.5 4.2 32.8 1.9 3.8 63.8 20.8 85.8 25.6 50.8 25.9 51.9 15.9 35.3 12.3 64.3 29.6 48.2 32.0 24.3 12.8 0.1 22.8 81.6 56.5 45.2 42.5 56.3 21.5 75.3 13.0 0.1 32.3 26.5 24.4 2.2 30.2 41.2 28.0 54.7 34.4 42.9 46.2 9.9 18.8 0.3 70.8 73.1 4.9 25.6 39.6 13.7 21.2 0.1 81.5 17.3 47.4 15.9 67.9 63.9 39.5 18.7 37.7 19.4 34.8 16.2 36.7 92.9 75.4 75.5 84.1 0.1 0.1 0.2 108.7 7.1 102.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 183.3 96.0 0.0 227.7 272.0 20.8 17.0 23.4 16.6 2.3 75.5 85.8 0.5 0.0 0.0 26.1 0.1 9.7 10.5 16.6 15.4 7.7 3.0 10.0 2.9 1.5 6.3 11.0 4.2 0.1 5.3 0.8 5.9 7.9 0.4 27.8 10.5 1.0 1.2 14.7 40.9 2.9 1.6 9.1 1.1 12.4 3.8 4.4 0.7 0.5 3.7 112.7 42.5 1.0 0.0 0.6 5.8 0.9 1.2 2.5 5.4 2.8 9.8 19.2 0.0 8.0 7.8 5.3 0.1 1.5 1.3 11.0 0.2 17.3 9.7 4.3 0.0 4.2 19.0 0.0 1.9 6.0 7.0 0.5 2.6 1.2 0.5 3.3 NECTIN4 "LNIR, nectin-4, PRR4, PVRL4" ENSG00000143217 "Nectin cell adhesion molecule 4" Q96NY8 1 161070998-161089558 "Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 98.9;skin 1: 113.6;vagina: 57.3" "Cell type enriched" "Detected in some" 5 "Syncytiotrophoblasts: 384.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 56.5;HaCaT: 37.0;MCF7: 24.0;OE19: 24.6;SK-BR-3: 47.8;T-47d: 31.1" "Low region specificity" "Detected in all" "Not detected" "Not detected" HPA010775 Enhanced Supported "Plasma membrane" "Secreted in other tissues" No No 170000 "Cluster 1: Neutrophils - Mixed function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA010775: AB_1079720" "unprognostic (1.09e-3)" "unprognostic (1.52e-1)" "unprognostic (3.51e-1)" "unprognostic (1.11e-2)" "unprognostic (5.69e-3)" "unprognostic (2.09e-2)" "unprognostic (6.69e-3)" "unprognostic (1.02e-1)" "unprognostic (1.69e-1)" "unprognostic (1.18e-1)" "unprognostic (6.49e-3)" "unprognostic (1.13e-1)" "unprognostic (2.24e-8)" "unprognostic (2.98e-2)" "unprognostic (2.43e-1)" "unprognostic (3.68e-2)" "unprognostic (4.97e-2)" 0.4 0.1 0.1 0.5 0.1 0.7 13.7 0.3 0.2 26.5 0.0 1.5 0.7 1.2 6.9 98.9 2.9 3.8 0.1 0.1 0.0 3.1 0.1 3.5 0.1 0.1 0.1 0.0 4.5 0.4 0.6 12.2 0.1 9.4 1.7 0.1 33.6 4.3 0.6 113.6 0.6 0.1 0.0 0.0 8.8 0.6 0.3 0.8 0.2 0.0 14.5 16.8 57.3 0.4 10.9 0.4 0.0 0.1 0.0 0.1 56.5 0.1 0.1 0.1 0.2 0.0 14.6 0.0 0.2 0.0 0.1 37.0 0.0 1.2 0.2 0.0 0.5 0.0 0.8 11.1 0.0 0.1 0.7 0.0 14.6 3.0 3.6 0.1 0.0 0.0 0.0 0.1 0.1 24.0 0.1 0.1 0.1 24.6 0.0 0.0 0.0 0.1 0.0 17.5 0.0 0.2 0.2 47.8 0.0 6.4 31.1 0.0 0.0 0.1 2.4 0.5 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.2 0.1 0.0 0.1 0.1 0.1 0.0 0.3 0.4 0.2 6.4 9.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 41.6 17.8 0.0 0.0 8.1 16.5 0.0 39.4 0.4 0.0 0.0 41.7 0.0 28.1 2.9 0.6 0.0 0.0 0.0 30.0 67.1 1.2 0.0 43.1 0.0 0.0 0.0 0.0 6.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 67.1 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 384.2 0.4 0.1 0.0 0.0 NID2 ENSG00000087303 "Nidogen 2" Q14112 14 52004803-52069228 "Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 60.8" "Cell type enhanced" "Detected in many" "Adipocytes: 31.0;Endothelial cells: 19.7;Fibroblasts: 46.0;Microglial cells: 19.7;Smooth muscle cells: 22.6;Theca cells: 19.1" "Cancer enhanced" "Detected in all" "thyroid cancer: 15.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 285.4;ASC TERT1: 113.0;BJ: 152.1;BJ hTERT+: 131.8;HHSteC: 158.1;HSkMC: 591.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052460, HPA058772" Enhanced Enhanced "Plasma membrane" "Secreted to extracellular matrix" NA NA 6300000 "Cluster 28: Placenta - Pregnancy" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane" "HPA052460: AB_2681840, HPA058772: AB_2683815" "unprognostic (6.51e-2)" "unprognostic (3.55e-3)" "unprognostic (3.73e-2)" "unprognostic (3.25e-2)" "unprognostic (2.04e-1)" "unprognostic (1.94e-1)" "unprognostic (5.37e-2)" "unprognostic (3.05e-3)" "unprognostic (2.52e-3)" "unprognostic (3.07e-2)" "unprognostic (4.85e-2)" "unprognostic (1.43e-1)" "unprognostic (1.48e-3)" "prognostic unfavorable (7.34e-4)" "unprognostic (4.58e-2)" "unprognostic (2.87e-2)" "prognostic unfavorable (2.78e-4)" 28.3 5.2 0.9 9.2 1.2 0.7 9.6 0.6 1.4 7.5 44.0 8.8 2.3 17.4 5.8 5.4 6.7 19.0 15.6 1.4 0.5 4.8 5.9 6.1 3.5 1.8 0.6 18.9 3.4 13.2 2.5 60.8 0.5 8.4 6.8 0.1 3.6 10.4 4.3 1.7 3.5 11.4 1.1 1.9 6.8 1.4 0.9 2.1 31.6 5.5 1.4 15.4 5.4 1.6 0.0 3.4 76.6 0.0 285.4 113.0 0.2 152.1 131.8 14.5 15.0 0.4 0.0 0.0 22.2 17.3 0.0 10.7 9.9 0.1 3.9 0.1 2.0 0.0 3.0 0.0 158.1 0.0 0.0 591.5 0.0 59.6 0.1 82.5 8.1 0.1 0.0 0.0 8.6 0.0 0.0 0.4 3.3 0.0 5.1 23.5 0.2 0.1 19.9 0.0 0.0 1.8 0.0 0.1 0.0 10.0 0.0 0.0 0.9 54.4 0.6 33.0 0.0 0.0 0.0 0.1 17.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.2 0.6 1.4 1.4 0.5 1.8 0.6 0.5 1.1 0.9 1.6 31.0 0.0 0.0 0.0 0.2 0.6 0.2 0.0 0.6 1.4 0.2 0.3 2.1 0.0 0.0 1.8 0.0 0.7 0.7 3.7 0.0 0.1 14.0 1.5 11.3 19.7 0.0 0.0 0.8 0.0 1.1 46.0 1.1 0.4 1.3 0.4 8.6 0.0 1.6 0.0 1.7 2.0 0.0 0.3 1.2 4.4 6.2 0.3 3.6 19.7 1.0 0.0 0.0 2.0 4.8 0.2 1.3 8.6 0.1 0.2 1.7 0.4 0.0 0.8 6.6 6.1 22.6 0.2 0.1 0.1 1.0 0.8 0.4 19.1 3.0 0.2 NMUR2 NMU2R ENSG00000132911 "Neuromedin U receptor 2" Q9GZQ4 5 152391546-152433368 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 6.2" "Group enriched" "Detected in some" 13 "Gastric mucus-secreting cells: 5.1;Oligodendrocytes: 8.5" "Cancer enhanced" "Detected in some" "pancreatic cancer: 1.8;stomach cancer: 2.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 9.6" "Region enhanced" "Detected in single" "hypothalamus: 1.7" "Low region specificity" "Detected in all" "HPA027800, HPA045836" Enhanced Supported "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA027800: , HPA045836: AB_10968856" "unprognostic (1.82e-1)" "unprognostic (3.83e-1)" "unprognostic (2.66e-1)" "unprognostic (9.29e-2)" "unprognostic (5.87e-2)" "unprognostic (6.44e-3)" "unprognostic (3.13e-1)" "unprognostic (6.47e-2)" "unprognostic (5.63e-2)" "unprognostic (8.20e-3)" "unprognostic (8.90e-5)" "unprognostic (1.48e-2)" "unprognostic (9.24e-2)" "unprognostic (9.56e-2)" "unprognostic (2.29e-1)" 0.0 0.1 1.0 0.0 3.5 0.0 0.0 1.4 1.8 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.7 3.0 0.4 0.0 0.3 0.0 4.5 2.1 0.0 0.0 0.0 0.1 0.0 4.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.8 0.0 1.0 1.5 3.0 0.6 0.5 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.4 9.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 1.2 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.5 1.4 1.8 0.7 3.0 4.5 2.1 4.1 3.8 3.0 6.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 5.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 NPTN "GP55, GP65, np55, np65, SDFR1, SDR1" ENSG00000156642 Neuroplastin Q9Y639 15 73560014-73634134 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 216.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051497, HPA072453" Approved Approved "Plasma membrane" NA No 15000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA051497: AB_2681507, HPA072453: AB_2686523" "unprognostic (9.30e-3)" "unprognostic (1.70e-1)" "unprognostic (5.01e-2)" "unprognostic (4.14e-1)" "unprognostic (3.11e-2)" "unprognostic (7.42e-3)" "unprognostic (9.74e-2)" "unprognostic (9.67e-2)" "unprognostic (3.63e-2)" "unprognostic (1.68e-1)" "unprognostic (3.57e-2)" "unprognostic (1.93e-1)" "unprognostic (1.60e-3)" "unprognostic (5.55e-2)" "unprognostic (7.41e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" 84.6 95.7 81.4 75.9 104.4 32.7 82.6 52.1 176.7 112.4 72.4 133.0 134.9 180.7 150.9 133.9 135.0 97.2 196.4 122.6 65.6 126.5 74.0 110.5 48.7 42.9 42.2 79.1 96.6 167.2 47.1 123.1 39.8 170.8 142.0 135.5 101.0 204.4 51.2 68.1 124.9 298.4 28.5 71.8 96.4 69.2 60.4 42.6 112.4 70.1 69.4 140.6 84.9 87.9 101.9 179.1 100.9 74.5 201.6 180.7 141.1 229.1 373.5 258.3 228.4 122.4 317.7 58.7 133.0 331.2 319.2 411.1 164.4 191.3 147.6 105.6 109.3 46.7 83.3 110.2 143.1 72.6 124.9 149.1 165.2 167.4 100.7 254.8 139.5 52.0 26.7 65.2 187.2 81.2 32.4 45.3 93.5 127.3 63.3 52.1 115.8 49.9 353.7 148.3 61.6 19.2 222.4 122.4 151.3 249.6 110.9 97.7 159.0 199.7 133.8 116.0 135.8 56.5 113.8 51.4 185.8 111.0 140.0 5.9 13.5 13.8 6.4 18.5 5.2 3.8 3.6 5.9 5.3 2.9 3.6 4.2 28.0 3.9 14.8 5.5 4.3 13.6 81.4 104.4 52.1 176.7 122.6 65.6 42.9 42.2 39.8 28.5 60.4 87.9 67.1 76.9 66.0 72.1 18.3 65.0 27.0 43.3 51.2 93.0 50.5 45.7 106.9 48.6 60.6 82.8 50.1 7.0 28.8 133.8 1.9 18.1 3.7 73.4 46.7 44.6 103.0 7.4 216.6 24.0 9.2 64.5 41.3 92.1 28.4 33.9 50.0 43.1 25.0 38.7 162.7 90.9 42.7 77.4 46.6 9.9 15.2 61.8 42.7 86.2 43.4 41.2 12.3 63.8 67.4 41.4 66.7 38.4 20.2 26.9 52.3 20.7 92.1 49.7 19.7 35.5 74.0 11.7 10.8 61.9 54.6 6.8 23.9 35.3 52.6 30.7 NRAS N-ras ENSG00000213281 "NRAS proto-oncogene, GTPase" P01111 1 114704469-114716771 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" Hydrolase "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010157, HPA049830, CAB079912" Uncertain Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "CAB010157: AB_632073, CAB079912: AB_2784586, HPA049830: AB_2680903" "unprognostic (4.75e-2)" "unprognostic (2.81e-1)" "unprognostic (1.09e-3)" "unprognostic (2.11e-2)" "unprognostic (8.59e-3)" "unprognostic (1.14e-1)" "prognostic unfavorable (3.03e-7)" "unprognostic (7.76e-3)" "unprognostic (1.57e-2)" "unprognostic (1.01e-3)" "prognostic unfavorable (1.36e-4)" "unprognostic (6.60e-3)" "prognostic unfavorable (7.87e-4)" "unprognostic (2.68e-1)" "unprognostic (1.30e-1)" "unprognostic (1.16e-1)" "unprognostic (3.33e-2)" 19.0 9.1 10.3 25.7 11.2 58.5 18.0 11.5 12.3 12.5 8.6 27.8 21.5 12.4 7.8 20.7 10.3 17.2 8.3 10.2 12.2 20.9 24.9 18.5 30.4 12.3 12.1 9.6 11.4 9.0 4.3 28.3 12.3 11.4 26.6 6.6 10.9 7.1 7.7 19.8 22.5 14.1 11.7 18.6 21.8 9.6 11.4 39.0 16.1 7.8 29.7 22.2 8.6 13.4 93.7 24.9 65.2 24.9 26.4 56.3 46.5 43.5 48.4 79.5 89.0 50.4 33.9 70.4 56.3 58.9 55.4 26.0 88.2 70.6 113.4 96.5 34.2 47.8 34.5 60.2 52.3 120.0 71.0 51.1 56.1 91.5 66.2 25.0 102.8 54.6 77.3 78.5 71.0 248.9 83.5 46.4 111.0 30.2 17.9 62.9 116.0 44.1 70.6 49.5 39.4 59.0 44.7 36.4 107.1 75.4 31.9 96.2 79.2 43.3 82.2 81.5 90.3 137.7 101.6 81.6 86.4 64.6 159.0 38.7 12.8 12.6 11.7 19.2 10.5 12.8 9.3 11.6 12.6 10.5 9.9 12.9 3.4 15.5 17.6 9.6 13.4 13.1 10.3 11.2 11.5 12.3 10.2 12.2 12.3 12.1 12.3 11.7 11.4 13.4 22.7 16.0 16.5 8.1 25.9 30.7 31.2 23.1 15.4 5.2 18.5 13.6 5.6 18.6 19.3 22.0 8.4 22.4 27.7 49.2 13.7 34.1 3.9 22.9 24.7 29.2 24.6 31.6 5.8 31.5 50.4 16.1 29.0 38.0 31.1 22.2 33.2 29.7 49.2 5.0 5.2 28.1 30.5 44.9 30.7 5.9 8.1 30.4 23.2 9.4 41.6 7.8 22.6 5.0 8.1 51.4 32.9 6.4 39.6 30.6 28.1 39.4 23.1 3.3 6.6 12.8 15.3 7.3 15.4 24.6 36.2 31.2 21.9 13.8 28.8 40.2 NRXN1 "Hs.22998, KIAA0578" ENSG00000179915 "Neurexin 1" "P58400, Q9ULB1" 2 49918503-51225575 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Angiogenesis, Cell adhesion" "Mental retardation, Schizophrenia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 13 "brain: 145.0" "Group enriched" "Detected in many" 5 "Astrocytes: 4025.1;Excitatory neurons: 3206.3;Inhibitory neurons: 2116.2;Oligodendrocyte precursor cells: 4897.8" "Cancer enriched" "Detected in single" 8 "glioma: 3.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 13 "granulocytes: 1.3" "Cell line enriched" "Detected in some" 7 "SCLC-21H: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071400 Supported "Plasma membrane" "Intracellular and membrane" NA NA 1400000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA071400: AB_2732180" "unprognostic (7.01e-2)" "unprognostic (9.96e-2)" "unprognostic (7.68e-2)" "unprognostic (1.74e-4)" "unprognostic (2.46e-1)" "unprognostic (8.95e-2)" "unprognostic (2.02e-2)" "unprognostic (1.85e-1)" "unprognostic (8.19e-2)" "unprognostic (6.37e-4)" "unprognostic (2.85e-2)" "unprognostic (6.68e-7)" "unprognostic (3.40e-2)" "unprognostic (1.75e-1)" "unprognostic (5.57e-2)" "unprognostic (1.99e-3)" 1.1 2.0 40.9 1.1 60.9 0.3 0.8 145.0 74.4 2.2 0.0 11.3 0.9 1.1 3.0 2.0 0.8 1.2 5.2 62.7 16.8 0.4 0.5 0.4 0.3 0.0 2.2 0.9 1.4 0.0 6.0 0.0 7.2 2.8 2.6 7.2 2.4 8.4 0.2 0.9 2.6 1.0 4.7 0.2 2.3 5.6 15.7 1.2 0.6 0.8 0.2 2.3 3.1 22.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 31.3 1.2 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.2 3.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 40.9 60.9 145.0 74.4 62.7 16.8 0.0 2.2 7.2 4.7 15.7 22.0 0.1 0.0 0.0 4025.1 0.0 0.0 0.3 0.0 3.4 116.0 3.1 3.7 19.4 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.9 0.1 201.6 0.1 2.8 1.0 1.8 0.0 3206.3 0.0 0.0 2.3 0.0 0.1 0.0 0.2 3.3 0.2 0.1 77.4 2116.2 0.0 0.0 0.0 0.6 103.4 2.5 0.6 1.8 174.3 0.0 22.7 0.0 4897.8 678.0 0.2 0.0 0.7 1.4 0.5 0.0 0.2 0.0 9.7 0.0 2.5 1.3 13.3 5.8 0.6 0.1 0.3 0.1 0.1 0.0 0.1 NTNG1 "KIAA0976, Lmnt1" ENSG00000162631 "Netrin G1" Q9Y2I2 1 107140007-107484923 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 75.1" "Cell type enhanced" "Detected in many" "Bipolar cells: 59.7;Excitatory neurons: 122.1;Inhibitory neurons: 162.5;Oligodendrocyte precursor cells: 425.3" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in all" "thalamus: 75.1" "Immune cell enhanced" "Detected in single" "memory B-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 48.7;fHDF/TERT166: 25.0;RPTEC TERT1: 27.4;U-138 MG: 21.8;U-251 MG: 16.9;U-87 MG: 24.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "hippocampal formation: 19.7;midbrain: 61.3;pons: 56.0;thalamus: 76.4" HPA065954 Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA065954: AB_2685585" "unprognostic (1.79e-1)" "unprognostic (4.63e-2)" "unprognostic (1.67e-2)" "unprognostic (9.38e-5)" "unprognostic (1.93e-3)" "unprognostic (9.87e-3)" "unprognostic (3.34e-1)" "unprognostic (8.38e-3)" "unprognostic (1.03e-1)" "unprognostic (2.02e-1)" "unprognostic (5.68e-2)" "unprognostic (2.05e-2)" "unprognostic (3.10e-4)" "unprognostic (2.00e-1)" "unprognostic (1.52e-1)" "unprognostic (1.93e-5)" 3.1 4.4 17.2 0.2 3.8 0.0 0.2 6.3 6.7 3.2 0.0 2.2 0.0 0.6 0.0 0.1 0.4 0.6 0.1 7.8 15.2 8.8 0.0 3.8 0.4 5.8 28.3 0.4 0.1 0.1 2.5 1.1 4.6 3.4 0.4 10.3 0.2 4.7 0.0 1.3 0.4 0.1 3.2 0.3 0.2 0.4 75.1 0.5 0.1 0.2 0.6 4.0 1.8 2.7 0.0 0.0 2.8 0.0 5.0 48.7 0.0 13.9 2.1 1.2 1.1 0.0 0.0 0.0 0.6 25.0 0.0 0.0 0.0 1.5 2.8 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 13.9 0.3 3.5 1.8 14.7 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 1.0 0.0 6.1 0.0 3.1 0.0 27.4 0.0 0.3 0.4 0.0 0.0 0.0 0.8 0.0 0.1 0.2 21.8 4.3 8.1 16.9 0.1 0.0 0.0 24.8 0.0 2.5 0.3 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.0 0.0 17.2 3.8 6.3 6.7 7.8 15.2 5.8 28.3 4.6 3.2 75.1 2.7 0.2 0.0 0.0 46.4 3.1 0.5 6.5 0.4 0.0 59.7 0.1 0.0 0.9 0.0 0.2 7.3 0.0 0.1 0.0 0.0 0.0 0.0 10.5 0.1 0.8 0.9 0.0 0.0 122.1 0.0 0.0 2.8 0.0 0.4 0.0 6.1 0.4 0.0 0.0 0.0 162.5 0.0 6.1 0.0 1.3 1.8 8.1 0.0 1.8 18.7 0.0 1.0 0.0 425.3 2.5 0.3 0.0 0.0 1.0 1.1 0.0 0.0 0.0 2.9 6.6 0.2 2.7 0.2 1.1 0.1 0.6 0.0 0.1 7.2 0.0 4.3 NTRK2 TRKB ENSG00000148053 "Neurotrophic receptor tyrosine kinase 2" Q16620 9 84668551-85027054 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, RAS pathway related proteins" "Differentiation, Neurogenesis" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 230.0;thyroid gland: 116.9" "Cell type enhanced" "Detected in many" "Astrocytes: 1144.3;Excitatory neurons: 750.1;Inhibitory neurons: 877.7;Oligodendrocyte precursor cells: 557.9" "Group enriched" "Detected in many" 5 "glioma: 31.6;head and neck cancer: 8.0;lung cancer: 9.8;thyroid cancer: 26.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.7;HaCaT: 3.0;RPTEC TERT1: 9.7;SH-SY5Y: 11.2;SuSa: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007637, CAB010346, HPA074873" Enhanced Supported "Plasma membrane" NA NA 20000000 "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB010346: AB_2155274, HPA007637: AB_1080385, HPA074873: " "unprognostic (2.75e-3)" "unprognostic (3.48e-2)" "unprognostic (1.82e-2)" "unprognostic (3.26e-1)" "unprognostic (9.26e-2)" "unprognostic (2.56e-2)" "unprognostic (1.29e-2)" "unprognostic (9.16e-2)" "unprognostic (6.13e-2)" "unprognostic (1.05e-1)" "unprognostic (4.25e-2)" "unprognostic (2.18e-2)" "unprognostic (2.66e-2)" "unprognostic (1.20e-2)" "unprognostic (1.21e-2)" "unprognostic (1.31e-1)" "unprognostic (1.39e-3)" 40.5 2.7 201.9 1.7 177.8 0.1 62.2 133.3 190.6 9.8 69.8 5.9 0.4 3.9 3.9 8.2 5.6 33.3 15.2 173.3 230.0 20.4 1.8 10.0 3.1 119.4 218.9 9.7 34.3 2.5 10.1 1.8 151.7 4.7 3.6 41.2 14.4 19.1 2.9 11.6 1.6 3.3 116.6 10.9 1.9 2.4 222.1 4.0 116.9 13.8 4.3 4.9 12.0 117.7 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 1.4 0.0 0.2 0.0 0.0 3.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 9.7 0.7 0.7 11.2 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.1 0.0 0.3 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 201.9 177.8 133.3 190.6 173.3 230.0 119.4 218.9 151.7 116.6 222.1 117.7 17.4 0.0 0.5 1144.3 0.7 56.6 1.0 1.8 93.9 30.3 144.1 116.8 11.4 0.0 0.2 9.2 6.2 0.0 1.0 8.7 27.4 36.1 1.8 1.2 0.4 8.0 0.0 0.0 750.1 0.7 0.1 76.6 0.0 2.3 0.0 0.1 5.0 0.0 0.2 242.3 877.7 0.7 0.0 0.0 14.2 3.6 104.1 1.4 17.8 65.6 0.6 241.0 0.0 557.9 109.5 0.5 7.0 48.2 0.3 0.9 0.0 7.1 1.7 12.2 124.9 9.9 114.4 0.8 2.3 5.2 24.6 0.0 3.3 0.2 7.2 0.9 NTSR1 NTR ENSG00000101188 "Neurotensin receptor 1" P30989 20 62708836-62762771 "G-protein coupled receptors, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 18 "brain: 11.2;intestine: 11.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.4;Cardiomyocytes: 1.1;Excitatory neurons: 1.6;Inhibitory neurons: 1.3;Kupffer cells: 2.9;Microglial cells: 1.0;monocytes: 1.4" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.9" "Region enriched" "Detected in many" 7 "midbrain: 11.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "PC-3: 57.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA050299 Supported "Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA050299: " "unprognostic (4.14e-2)" "unprognostic (2.02e-2)" "unprognostic (2.75e-2)" "unprognostic (8.87e-4)" "unprognostic (9.27e-3)" "unprognostic (1.45e-1)" "unprognostic (4.17e-2)" "unprognostic (2.80e-3)" "unprognostic (7.16e-2)" "unprognostic (3.10e-3)" "unprognostic (3.55e-2)" "unprognostic (2.53e-1)" "unprognostic (1.27e-2)" "unprognostic (1.25e-1)" "unprognostic (1.29e-1)" "unprognostic (1.17e-1)" "unprognostic (2.49e-1)" 0.0 0.0 1.1 0.0 1.5 0.6 0.0 0.0 1.4 0.0 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.4 0.0 0.0 0.0 0.0 0.4 11.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.2 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.5 0.0 0.0 2.0 10.9 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.3 0.0 0.0 2.8 0.2 2.7 0.3 1.1 57.7 1.8 0.0 9.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 10.8 7.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 1.5 0.0 1.4 1.4 0.4 0.4 11.2 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 4.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.0 0.0 2.9 0.3 0.0 0.0 0.5 0.0 1.0 1.4 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 OR10P1 "OR10P1P, OR10P2P, OR10P3P, OST701" ENSG00000175398 "Olfactory receptor family 10 subfamily P member 1" Q8NGE3 12 55636860-55637854 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA074114 Supported "Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA074114: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR2C3 "OR2C4, OR2C5P, OST742" ENSG00000196242 "Olfactory receptor family 2 subfamily C member 3" Q8N628 1 247524677-247536440 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 1.3;testis: 1.1" "Cell type enhanced" "Detected in some" "Early spermatids: 2.4;granulocytes: 1.3;Late spermatids: 3.7;Spermatocytes: 2.2" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.3" "Immune cell enriched" "Detected in single" 5 "basophil: 1.9" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA058578 Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA058578: AB_2683761" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (3.45e-2)" "unprognostic (1.03e-1)" 0.0 0.1 0.2 0.0 0.1 0.0 0.0 1.3 0.4 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 1.3 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 2.2 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 OR8S1 ENSG00000284723 "Olfactory receptor family 8 subfamily S member 1" Q8NH09 12 48525632-48528103 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Spermatocytes: 4.0;Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA045595 Uncertain Supported "Plasma membrane" NA NA "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" "HPA045595: AB_10964447" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 4.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSBPL6 ORP6 ENSG00000079156 "Oxysterol binding protein like 6" Q9BZF3 2 178194481-178402893 "Plasma proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 33.8;tongue: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 281.4;Excitatory neurons: 314.2;Inhibitory neurons: 404.2;Oligodendrocyte precursor cells: 134.2" "Cancer enhanced" "Detected in many" "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 48.8;hTERT-HME1: 50.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032131 Enhanced Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 80: Striated muscle - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032131: AB_10670963" "unprognostic (6.22e-2)" "unprognostic (1.53e-1)" "unprognostic (2.47e-1)" "unprognostic (5.95e-3)" "unprognostic (5.26e-2)" "unprognostic (1.40e-2)" "unprognostic (7.55e-2)" "unprognostic (4.81e-2)" "unprognostic (3.32e-1)" "unprognostic (1.03e-1)" "unprognostic (3.03e-3)" "unprognostic (3.49e-2)" "unprognostic (1.15e-5)" "unprognostic (1.11e-2)" "unprognostic (1.30e-1)" "unprognostic (3.73e-4)" "unprognostic (4.44e-6)" 1.3 1.5 4.1 1.0 6.1 0.2 1.7 3.7 16.3 1.1 0.0 1.0 0.7 0.8 0.7 2.4 1.0 1.1 3.8 6.1 8.0 2.7 5.6 4.0 1.1 5.7 6.9 1.4 1.2 0.8 6.7 0.6 5.3 3.1 1.0 8.4 2.2 1.5 33.8 8.7 3.5 1.4 1.7 1.0 0.8 1.3 7.5 1.6 2.3 20.3 0.8 1.0 1.5 8.3 0.0 1.1 8.3 16.9 6.8 7.5 6.3 13.9 7.2 12.0 14.6 1.4 0.2 0.0 0.5 12.9 6.6 0.3 19.6 11.4 20.2 0.2 10.2 48.8 2.9 0.0 4.4 8.0 0.3 5.0 17.6 26.4 50.8 4.3 5.8 6.2 0.9 5.8 15.9 7.0 0.1 0.0 10.0 0.0 10.2 0.0 16.9 3.2 0.9 0.0 6.3 3.8 6.2 1.8 13.7 9.2 2.4 0.1 11.4 13.7 8.5 9.3 16.3 31.8 13.4 0.0 16.3 0.0 6.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.1 4.1 6.1 3.7 16.3 6.1 8.0 5.7 6.9 5.3 1.7 7.5 8.3 0.7 0.0 7.2 281.4 0.0 13.3 2.1 1.3 7.4 59.4 2.1 1.7 15.2 4.3 6.5 0.0 25.0 0.2 0.0 0.1 1.9 0.6 1.0 4.4 1.0 1.7 1.8 0.0 314.2 0.8 4.9 4.3 0.0 0.4 7.0 2.0 0.0 6.2 3.9 1.7 404.2 6.0 4.1 3.5 1.0 1.1 0.0 0.7 5.4 62.8 0.0 10.6 0.0 134.2 10.3 0.2 0.0 1.5 1.5 2.2 9.5 6.2 78.2 6.9 0.0 25.4 5.8 0.1 2.1 6.4 20.9 0.1 0.9 14.5 1.4 0.5 OTOP2 ENSG00000183034 "Otopetrin 2" Q7RTS6 17 74922950-74933912 "Predicted membrane proteins, Transporters" "Hydrogen ion transport, Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "intestine: 20.1" "Cell type enriched" "Detected in some" 20 "Paneth cells: 627.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 41 "HDLM-2: 10.1" "Region enriched" "Detected in some" 12 "olfactory bulb: 12.7" "Low region specificity" "Detected in many" "HPA024524, HPA053090" Uncertain Approved "Plasma membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA024524: AB_2671592, HPA053090: AB_2682041" "unprognostic (1.62e-2)" "unprognostic (1.45e-1)" "unprognostic (7.25e-2)" "unprognostic (3.21e-2)" "unprognostic (3.62e-1)" "unprognostic (1.30e-1)" "unprognostic (2.85e-2)" "unprognostic (3.81e-1)" "unprognostic (9.04e-2)" "unprognostic (2.04e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.1 0.3 0.2 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.1 0.0 0.2 1.4 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 10.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 30.0 0.0 0.0 9.3 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.0 19.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 627.4 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 4.1 0.0 OXGR1 "aKGR, GPR80, GPR99, P2RY15, P2Y15" ENSG00000165621 "Oxoglutarate receptor 1" Q96P68 13 96985719-96994730 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in some" 13 "Extravillous trophoblasts: 49.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 6 "myeloid DC: 1.2;plasmacytoid DC: 2.1" "Lineage enriched" "Detected in single" 7 "dendritic cells: 2.1" "Cell line enhanced" "Detected in some" "RT4: 3.3;SK-BR-3: 1.4;U-2 OS: 1.6" "Not detected" "Not detected" HPA067673 Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "HPA067673: AB_2685883" "unprognostic (1.83e-1)" "unprognostic (1.01e-2)" "unprognostic (1.33e-1)" "unprognostic (6.97e-4)" "unprognostic (7.23e-2)" "unprognostic (1.52e-1)" "unprognostic (8.38e-2)" "unprognostic (2.16e-1)" "unprognostic (1.16e-1)" "unprognostic (2.22e-2)" "unprognostic (4.14e-2)" "unprognostic (3.88e-2)" "unprognostic (1.89e-1)" "unprognostic (2.75e-1)" "unprognostic (1.54e-1)" "unprognostic (9.68e-2)" 1.3 0.0 1.0 1.3 0.8 0.1 4.2 0.5 1.5 1.0 0.5 2.0 0.2 0.5 2.5 2.1 1.6 0.1 0.2 0.8 2.1 4.0 0.0 0.4 0.1 1.2 1.3 0.1 0.5 0.3 0.3 0.9 1.0 0.5 1.6 0.0 3.0 0.4 0.2 2.6 0.4 0.5 0.7 0.4 0.2 0.1 2.6 0.3 0.5 0.3 0.8 1.7 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.1 0.0 1.4 0.0 0.0 0.7 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.1 1.0 0.8 0.5 1.5 0.8 2.1 1.2 1.3 1.0 0.7 2.6 1.3 0.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.6 0.0 1.7 1.4 0.2 0.0 0.0 0.0 0.0 2.4 0.1 0.2 1.9 0.0 0.2 0.7 0.1 0.8 1.2 0.0 0.6 0.0 49.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.8 0.0 0.6 0.5 0.0 0.0 0.4 0.1 0.0 0.3 3.6 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.7 0.0 0.0 0.0 0.9 0.0 0.0 2.2 0.0 3.7 0.0 0.0 1.2 0.0 PANX1 "MRS1, PX1, UNQ2529" ENSG00000110218 "Pannexin 1" Q96RD7 11 94128841-94181968 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Calcium transport, Differentiation, Ion transport, Oogenesis, Transport" "Calcium channel, Ion channel" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 102.0;Suprabasal keratinocytes: 72.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016930 Uncertain Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" "HPA016930: AB_1854954" "unprognostic (1.65e-2)" "unprognostic (2.32e-2)" "unprognostic (2.41e-1)" "prognostic unfavorable (1.13e-4)" "unprognostic (1.16e-1)" "unprognostic (7.02e-2)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.09e-5)" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.00e-3)" "unprognostic (3.26e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.15e-2)" "unprognostic (9.45e-2)" "unprognostic (1.79e-1)" "unprognostic (1.26e-3)" 11.4 7.2 5.1 12.1 5.2 4.1 6.4 1.2 5.5 7.9 2.7 8.4 5.4 8.5 5.2 7.9 5.2 11.5 9.9 5.0 7.1 6.9 16.8 10.2 6.4 2.1 2.9 7.1 7.4 4.4 4.7 9.7 3.3 7.7 7.2 3.1 6.0 7.0 20.8 8.3 5.8 12.8 2.8 5.8 7.4 9.9 4.9 8.1 8.7 10.8 7.0 21.9 6.5 2.7 24.6 10.2 26.2 16.0 23.9 32.3 17.1 29.8 63.0 25.1 30.7 26.2 37.6 7.8 27.3 30.5 46.1 50.5 20.9 49.2 25.2 33.6 10.9 36.0 10.2 13.5 23.1 18.7 31.0 25.7 33.9 32.8 29.2 16.1 21.2 20.1 23.8 27.5 28.3 7.8 31.3 4.4 21.0 19.7 18.2 36.7 35.0 9.7 16.3 24.0 11.0 31.9 20.9 11.9 14.4 13.3 25.2 9.5 15.4 49.5 25.5 16.4 29.9 4.5 18.2 12.6 20.6 19.0 32.2 3.2 4.0 0.3 2.1 2.2 2.4 1.3 1.7 2.3 2.7 1.2 1.6 1.7 0.2 2.6 1.4 0.4 2.9 3.2 5.1 5.2 1.2 5.5 5.0 7.1 2.1 2.9 3.3 2.8 4.9 2.7 3.8 0.0 8.7 4.6 6.6 102.0 12.3 14.9 13.6 1.3 4.5 2.0 4.7 4.3 4.7 1.8 0.0 12.8 5.3 4.7 0.0 15.7 5.3 9.1 13.0 6.8 2.4 5.2 8.9 18.2 32.4 17.5 7.1 13.9 9.5 4.0 2.2 8.1 20.5 0.0 15.4 4.1 0.0 3.1 21.6 3.9 4.4 11.5 17.8 8.4 3.7 1.1 1.0 9.5 5.8 26.1 3.4 3.8 7.4 10.2 2.6 2.1 6.2 1.1 0.0 16.9 10.6 1.7 8.2 8.3 72.2 23.8 6.6 10.1 4.2 12.7 PANX2 "hPANX2, PX2" ENSG00000073150 "Pannexin 2" Q96RD6 22 50170731-50180295 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 51.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 11.4;Excitatory neurons: 13.3;Hepatocytes: 10.7;Inhibitory neurons: 15.8;Muller glia cells: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.9" "Lineage enhanced" "Detected in single" "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "EFO-21: 10.3;HDLM-2: 16.7;Hep G2: 19.6;MCF7: 10.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004624, HPA039117" Enhanced Supported "Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "HPA004624: , HPA039117: AB_10805354" "unprognostic (1.00e-1)" "unprognostic (7.25e-2)" "unprognostic (2.72e-2)" "unprognostic (1.05e-1)" "unprognostic (3.01e-3)" "unprognostic (2.11e-2)" "unprognostic (1.03e-1)" "unprognostic (1.48e-1)" "unprognostic (1.56e-1)" "unprognostic (4.43e-2)" "unprognostic (3.08e-1)" "unprognostic (1.23e-1)" "unprognostic (1.65e-9)" "unprognostic (2.23e-1)" "unprognostic (1.78e-1)" "unprognostic (3.00e-1)" "unprognostic (4.08e-1)" 1.0 0.8 4.4 0.5 4.4 1.6 1.0 8.4 40.1 1.7 0.0 0.3 0.0 1.2 0.5 5.2 2.2 0.4 0.7 8.0 13.1 3.0 9.6 2.1 0.0 51.0 8.8 3.4 1.4 0.3 7.9 0.1 48.4 3.9 0.0 1.6 5.0 1.4 0.7 1.1 0.2 0.0 7.9 1.9 0.4 1.7 14.1 0.0 7.3 0.1 0.1 1.4 1.9 16.4 0.9 2.1 0.4 2.3 0.0 0.2 4.9 2.6 2.5 0.5 0.4 0.5 8.0 0.0 10.3 0.3 1.4 0.5 1.3 1.0 0.1 16.7 1.4 0.4 3.5 19.6 0.7 0.1 1.2 0.2 1.0 0.7 0.0 1.1 0.6 0.0 1.4 0.0 0.2 10.8 0.0 1.0 3.9 0.0 4.2 1.0 0.0 4.0 0.0 1.6 9.8 0.9 1.6 0.2 6.5 0.5 0.7 0.8 4.5 0.5 4.1 6.7 4.9 1.8 0.1 0.6 0.3 0.0 7.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.6 0.0 0.0 4.4 4.4 8.4 40.1 8.0 13.1 51.0 8.8 48.4 7.9 14.1 16.4 0.0 0.0 1.1 7.2 0.3 0.5 3.1 0.6 0.0 11.4 2.5 2.4 0.8 1.5 2.6 0.0 0.0 0.0 1.5 0.0 5.9 2.3 0.3 5.9 1.5 0.7 0.0 0.4 13.3 2.8 0.2 0.8 0.0 7.0 0.0 2.1 0.0 10.7 0.1 0.0 15.8 0.0 0.0 0.9 1.5 0.2 0.0 1.1 0.0 1.9 1.8 29.7 0.0 6.6 1.2 1.8 0.0 1.2 0.5 6.0 0.0 3.0 3.0 3.6 0.0 0.1 0.9 0.0 1.8 0.3 0.3 0.0 0.2 0.1 0.0 4.5 PARD6G "PAR-6G, PAR6gamma" ENSG00000178184 "Par-6 family cell polarity regulator gamma" Q9BYG4 18 80157232-80247514 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 38.1" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 39.6;Oligodendrocyte precursor cells: 25.6;Squamous epithelial cells: 25.3;Suprabasal keratinocytes: 63.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HMC-1: 36.4;hTCEpi: 34.0;RT4: 27.9;U-2 OS: 28.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA047017 Uncertain Approved "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA047017: AB_2679904" "unprognostic (1.11e-1)" "unprognostic (4.39e-2)" "unprognostic (9.88e-2)" "unprognostic (4.40e-2)" "unprognostic (2.97e-1)" "unprognostic (5.48e-3)" "prognostic unfavorable (3.19e-4)" "unprognostic (1.80e-1)" "unprognostic (9.96e-2)" "unprognostic (4.27e-2)" "unprognostic (1.17e-1)" "unprognostic (4.09e-2)" "unprognostic (6.86e-3)" "unprognostic (9.65e-2)" "unprognostic (1.01e-1)" "unprognostic (4.85e-1)" "unprognostic (2.72e-1)" 3.4 1.7 5.8 1.4 5.7 0.6 5.3 3.8 7.9 9.6 6.8 6.0 1.8 6.5 2.7 18.0 6.2 3.3 2.9 9.3 7.8 7.0 3.5 2.9 2.5 6.3 5.8 6.2 2.1 2.1 3.8 5.5 5.5 5.7 2.0 1.8 4.5 5.9 1.9 38.1 3.0 5.4 4.6 2.0 2.7 2.1 8.3 5.3 18.0 1.0 4.3 5.6 12.0 5.9 3.0 4.3 17.7 13.4 0.6 0.7 12.9 3.3 0.7 2.9 0.4 1.2 1.2 0.0 1.4 1.5 5.1 13.4 6.4 19.2 2.8 0.5 5.7 0.2 3.5 10.4 0.8 4.0 36.4 5.7 34.0 0.3 1.8 2.2 1.4 4.2 1.4 0.8 4.3 5.0 3.6 0.4 5.3 1.4 5.2 0.1 11.7 1.5 0.5 27.9 7.4 7.7 4.1 2.2 20.0 8.6 2.6 3.4 1.1 5.9 28.8 2.2 1.6 0.9 1.2 0.3 1.9 0.9 11.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 5.7 3.8 7.9 9.3 7.8 6.3 5.8 5.5 4.6 8.3 5.9 3.3 3.2 0.6 7.5 0.7 39.6 13.7 11.0 18.8 1.3 4.1 10.3 2.8 1.5 2.3 3.7 0.0 0.6 9.7 0.4 0.0 0.4 0.5 9.8 10.1 8.2 0.0 0.0 6.5 0.2 9.5 4.1 0.5 3.3 0.0 3.1 10.8 1.5 0.8 0.0 8.5 0.7 8.2 0.9 6.5 0.7 1.8 0.8 12.4 15.9 0.0 2.0 0.0 25.6 4.8 0.8 0.0 1.9 3.6 6.6 0.0 7.6 2.6 2.5 19.7 1.9 13.6 1.5 6.0 25.3 63.9 0.4 8.0 2.0 0.6 13.4 PARP6 "ARTD17, pART17" ENSG00000137817 "Poly(ADP-ribose) polymerase family member 6" Q2NL67 15 72241181-72272999 "Metabolic proteins, Predicted intracellular proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 178.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026991 Approved Approved "Plasma membrane" Yes No "Cluster 45: Eosinophils - Innate immune response" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA026991: AB_1854989" "unprognostic (3.88e-2)" "prognostic favorable (3.17e-5)" "prognostic unfavorable (3.37e-4)" "unprognostic (3.36e-1)" "unprognostic (7.13e-2)" "unprognostic (3.05e-1)" "unprognostic (2.37e-2)" "unprognostic (1.33e-1)" "unprognostic (2.00e-1)" "unprognostic (2.64e-1)" "unprognostic (8.55e-2)" "unprognostic (6.92e-2)" "prognostic unfavorable (8.02e-8)" "unprognostic (6.81e-2)" "unprognostic (1.14e-1)" "unprognostic (1.45e-1)" "unprognostic (4.42e-2)" 20.0 20.9 63.2 14.6 64.8 30.5 20.0 62.2 84.6 22.2 61.2 28.7 15.3 24.5 24.0 17.7 22.6 21.3 19.6 64.5 57.7 23.8 15.5 19.7 19.4 55.7 55.9 29.2 32.5 12.6 49.7 18.3 55.3 25.1 14.8 52.9 23.2 17.3 34.8 23.0 21.7 20.2 51.0 20.6 24.2 34.5 57.1 21.0 30.2 21.2 17.4 22.7 19.1 64.9 15.9 27.6 29.0 37.8 30.5 25.2 23.7 13.8 19.9 21.8 31.1 18.5 28.2 22.3 8.4 20.3 31.4 20.9 32.4 18.1 12.4 26.5 30.6 31.7 55.0 0.2 25.4 16.7 30.1 32.6 43.5 20.1 55.2 33.7 14.6 35.6 16.6 24.3 17.5 28.4 14.4 28.7 14.2 13.2 0.0 26.7 20.8 17.2 19.9 30.4 81.4 43.1 22.6 17.8 37.0 38.2 22.8 18.8 14.0 26.7 24.7 35.7 20.7 27.9 27.7 23.2 19.1 31.4 19.1 1.1 3.6 8.2 2.3 3.1 1.6 2.4 1.7 2.5 2.6 2.3 2.6 2.0 3.6 3.0 3.5 2.2 2.9 2.1 63.2 64.8 62.2 84.6 64.5 57.7 55.7 55.9 55.3 51.0 57.1 64.9 11.5 22.4 21.2 54.9 15.3 14.4 9.6 6.9 31.3 16.4 13.0 13.7 20.9 2.8 12.9 9.2 20.9 7.3 12.0 8.0 7.9 9.7 61.4 8.0 10.3 11.1 17.4 4.6 19.7 12.7 5.3 13.9 21.4 10.0 15.8 17.3 6.4 6.1 8.9 18.5 20.5 6.5 6.1 14.8 11.1 178.1 12.5 14.0 16.0 20.6 9.3 8.8 6.2 27.2 54.6 9.2 9.0 9.8 12.3 9.0 17.7 12.3 5.8 15.5 6.6 13.7 12.5 44.3 12.6 19.3 15.8 6.4 13.3 8.6 7.5 9.3 PCBD2 "DCOH2, DCOHM" ENSG00000132570 "Pterin-4 alpha-carbinolamine dehydratase 2" Q9H0N5 5 134905120-135007959 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Tetrahydrobiopterin biosynthesis" Lyase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 49.4;tongue: 42.7" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036428 Uncertain Approved "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 6: T47d - Mammary gland" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA036428: AB_10670103" "unprognostic (3.70e-2)" "unprognostic (3.53e-2)" "unprognostic (3.54e-3)" "unprognostic (1.36e-2)" "unprognostic (2.92e-1)" "unprognostic (1.98e-1)" "unprognostic (4.22e-1)" "unprognostic (6.43e-2)" "unprognostic (4.49e-1)" "unprognostic (1.01e-1)" "unprognostic (1.22e-1)" "unprognostic (5.18e-2)" "unprognostic (1.87e-3)" "unprognostic (4.57e-2)" "unprognostic (6.34e-2)" "unprognostic (9.32e-3)" "unprognostic (1.50e-1)" 5.3 7.7 7.3 4.8 8.5 7.6 6.0 7.8 7.6 4.3 11.0 6.1 9.5 4.2 4.1 8.3 5.7 4.6 17.1 6.4 7.5 10.2 11.9 4.9 5.9 8.7 7.7 5.1 8.0 13.0 3.8 3.5 8.0 5.4 7.0 9.9 9.6 3.8 49.4 9.2 8.1 3.6 6.8 5.8 8.2 3.2 8.1 5.5 9.6 42.7 6.1 4.5 4.9 10.8 7.5 7.2 9.4 6.9 5.7 5.2 5.2 6.0 5.2 3.8 3.8 12.0 17.5 8.7 8.8 4.4 6.1 6.5 5.6 5.9 3.4 12.3 3.1 6.0 9.5 7.1 5.4 7.1 3.6 3.4 7.1 3.6 7.6 5.1 4.3 7.7 7.7 12.2 6.9 13.0 7.5 12.3 5.1 11.5 6.9 10.9 8.4 9.7 8.1 7.4 7.2 9.2 10.4 6.0 9.1 7.1 13.0 9.4 5.9 6.4 4.3 7.1 8.1 10.6 15.7 5.5 7.8 8.8 4.8 5.7 5.1 5.4 3.6 4.5 2.9 4.5 4.0 3.4 4.4 4.2 3.8 4.3 2.8 4.0 4.6 7.7 3.9 2.7 7.3 8.5 7.8 7.6 6.4 7.5 8.7 7.7 8.0 6.8 8.1 10.8 4.2 9.6 10.3 28.7 8.8 3.6 6.4 15.8 7.4 13.5 11.7 8.4 32.5 20.0 12.5 16.5 12.5 13.6 10.1 13.6 21.5 17.1 8.4 7.9 6.1 6.9 4.2 31.5 10.6 18.2 24.4 5.8 13.3 8.7 6.3 22.4 7.1 23.1 24.6 23.5 12.9 9.5 20.3 10.0 9.6 3.5 7.2 10.2 5.4 17.8 26.9 14.8 7.2 13.0 20.6 17.8 6.2 2.2 13.1 7.1 26.5 26.3 11.9 45.9 0.0 9.0 7.4 5.2 11.5 13.8 6.0 10.1 7.8 9.5 15.9 8.7 PCDHA1 ENSG00000204970 "Protocadherin alpha 1" Q9Y5I3 5 140786136-141012347 "Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.9;pituitary gland: 1.0;testis: 1.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Alveolar cells type 2: 2.2;Hepatic stellate cells: 1.4;Sertoli cells: 6.6;Spermatogonia: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "T-47d: 9.1" "Low region specificity" "Detected in many" HPA035969 Enhanced Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 6: T47d - Mammary gland" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA035969: AB_10673492" "unprognostic (2.76e-5)" "unprognostic (1.19e-1)" "unprognostic (3.74e-2)" "unprognostic (1.09e-4)" "unprognostic (7.38e-2)" "unprognostic (2.86e-2)" "unprognostic (2.26e-3)" "unprognostic (1.25e-2)" "unprognostic (1.91e-2)" "unprognostic (1.81e-1)" "unprognostic (9.01e-5)" "unprognostic (2.46e-2)" "unprognostic (1.91e-1)" "unprognostic (7.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.77e-3)" "unprognostic (1.29e-1)" 0.0 0.2 0.2 0.0 0.5 0.0 0.1 1.5 1.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.1 0.0 0.0 0.0 1.5 0.7 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.9 0.0 0.0 1.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.4 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.6 0.0 0.1 1.1 0.1 9.1 0.3 0.0 1.0 0.6 0.4 0.0 0.0 0.0 0.0 0.2 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.5 1.5 1.0 0.7 0.4 1.5 0.7 1.1 0.9 0.5 1.9 0.0 3.2 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PCDHB11 "ME2, PCDH-BETA11" ENSG00000197479 "Protocadherin beta 11" Q9Y5F2 5 141199610-141203779 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 3.2;Bipolar cells: 4.9;Endometrial stromal cells: 3.5;Fibroblasts: 4.8;Peritubular cells: 3.4;Sertoli cells: 6.6;Skeletal myocytes: 4.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 5.6;EFO-21: 8.9;U-2 OS: 3.0" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.32e-1)" "unprognostic (3.47e-2)" "unprognostic (7.21e-2)" "unprognostic (1.76e-1)" "unprognostic (1.18e-1)" "unprognostic (1.56e-1)" "unprognostic (2.82e-2)" "unprognostic (1.42e-1)" "unprognostic (6.78e-2)" "unprognostic (1.29e-2)" "unprognostic (1.07e-1)" "unprognostic (2.89e-1)" "unprognostic (3.87e-3)" "unprognostic (4.96e-2)" "unprognostic (1.37e-2)" "unprognostic (9.79e-2)" "unprognostic (6.47e-3)" 1.3 0.6 0.2 0.5 0.5 0.2 0.9 0.9 1.2 1.2 0.0 1.0 0.2 1.5 0.5 0.7 0.9 0.9 0.8 0.5 0.0 0.7 0.2 0.8 0.1 0.3 0.3 1.6 2.6 2.6 0.7 0.6 0.1 0.9 0.3 0.6 0.8 1.0 0.4 0.8 0.4 1.2 0.4 0.6 0.6 0.4 0.0 0.3 0.6 0.6 0.1 0.9 0.6 0.4 0.0 0.1 1.8 5.6 0.1 0.1 1.1 0.1 0.5 0.0 0.0 0.0 0.1 0.0 8.9 0.5 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.8 0.0 0.1 0.0 1.4 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.0 2.2 0.0 0.0 0.2 2.2 0.3 1.3 0.1 0.7 0.3 1.3 0.0 0.3 0.1 3.0 2.4 0.0 0.1 0.0 0.0 1.4 0.1 1.5 0.6 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.5 0.2 0.0 0.1 0.0 0.0 0.2 0.5 0.9 1.2 0.5 0.0 0.3 0.3 0.1 0.4 0.0 0.4 1.9 3.2 0.5 0.0 0.0 0.0 0.7 0.0 0.0 4.9 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.7 3.5 1.9 2.4 0.0 0.0 1.8 0.0 4.8 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.1 0.1 1.8 0.0 0.0 2.0 0.0 0.0 0.0 1.0 0.0 3.4 0.1 0.9 0.0 0.9 0.0 0.2 6.6 4.1 1.7 0.1 0.1 0.2 0.3 0.0 0.1 0.0 0.0 0.7 PCDHB12 PCDH-BETA12 ENSG00000120328 "Protocadherin beta 12" Q9Y5F1 5 141208697-141212571 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 4.0;Endometrial stromal cells: 2.8;Fibroblasts: 2.8;Melanocytes: 3.6;Peritubular cells: 2.6;Skeletal myocytes: 2.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 2.7;ASC diff: 2.5;EFO-21: 3.0;RH-30: 3.2;U-2 OS: 2.3;U-2197: 2.4" HPA045042 Uncertain Approved "Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA045042: AB_2679194" "unprognostic (1.43e-2)" "unprognostic (3.22e-3)" "unprognostic (4.18e-3)" "unprognostic (8.43e-2)" "unprognostic (3.95e-3)" "unprognostic (7.87e-3)" "unprognostic (1.46e-1)" "unprognostic (2.95e-2)" "unprognostic (3.63e-1)" "unprognostic (9.13e-3)" "unprognostic (4.86e-2)" "unprognostic (2.94e-2)" "unprognostic (4.37e-3)" "unprognostic (3.22e-3)" "unprognostic (4.97e-3)" "unprognostic (3.83e-2)" "unprognostic (6.41e-3)" 1.3 0.6 0.1 0.4 0.7 0.0 1.2 0.9 1.1 1.9 0.0 1.3 0.2 2.7 0.8 0.4 1.9 1.0 1.4 0.8 0.1 0.6 0.3 1.4 0.1 0.3 0.3 2.2 1.3 1.0 2.0 0.4 0.0 0.9 0.4 0.8 0.6 0.9 0.7 0.5 0.6 1.8 0.1 0.7 0.6 1.1 0.1 0.1 0.6 0.9 0.1 1.2 1.1 0.7 0.0 0.0 0.7 2.7 2.5 1.4 0.4 0.0 1.9 0.1 0.2 0.0 0.0 0.0 3.0 0.3 1.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.6 0.0 0.0 0.7 0.2 0.0 0.0 0.6 0.7 0.1 0.0 0.0 0.1 0.0 0.5 0.5 3.2 0.0 0.0 0.0 1.5 0.9 0.0 0.0 0.6 0.2 2.1 0.4 0.2 0.4 2.3 2.4 0.0 0.0 0.0 0.0 1.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.9 1.1 0.8 0.1 0.3 0.3 0.0 0.1 0.1 0.7 1.9 0.0 1.1 0.0 0.0 0.4 0.0 0.2 0.0 4.0 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.8 0.1 2.8 1.3 1.8 0.0 0.0 0.9 0.0 2.8 0.5 0.1 0.0 0.1 1.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.4 1.2 0.0 3.6 0.0 0.0 1.2 0.0 0.0 0.0 0.3 0.0 2.6 0.0 0.1 0.0 0.2 0.0 0.3 0.0 2.2 1.6 1.2 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 PCDHGC3 "PC-43, PC43, PCDH-GAMMA-C3, PCDH2" ENSG00000240184 "Protocadherin gamma subfamily C, 3" Q9UN70 5 141475947-141512977 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 308.1" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 8.0;Bipolar cells: 8.4;Endometrial stromal cells: 5.5;Fibroblasts: 10.2;Horizontal cells: 11.8;Skeletal myocytes: 6.6" "Group enriched" "Detected in all" 6 "glioma: 55.0;melanoma: 20.7" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 24 "plasmacytoid DC: 15.3" "Lineage enriched" "Detected in single" 24 "dendritic cells: 15.3" "Cell line enhanced" "Detected in many" "ASC diff: 200.7;HSkMC: 186.2;U-138 MG: 244.1;WM-115: 382.2" "Low region specificity" "Detected in all" "HPA008755, HPA010580, HPA077289" Approved Approved "Plasma membrane" NA NA 1200000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA008755: AB_1079577, HPA010580: AB_2732401, HPA077289: AB_2686832" "unprognostic (2.52e-1)" "unprognostic (4.83e-3)" "unprognostic (1.17e-1)" "unprognostic (6.76e-2)" "unprognostic (3.76e-1)" "unprognostic (3.44e-2)" "unprognostic (4.30e-1)" "unprognostic (1.87e-1)" "unprognostic (1.70e-1)" "prognostic unfavorable (6.19e-4)" "unprognostic (2.03e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (8.18e-4)" "unprognostic (3.72e-2)" "unprognostic (5.66e-2)" "unprognostic (9.55e-2)" "prognostic unfavorable (6.00e-4)" 63.3 64.3 248.0 15.4 241.0 0.2 59.9 221.6 308.1 107.8 165.1 60.4 7.4 81.3 60.8 54.5 62.6 30.2 77.8 232.3 227.5 36.6 29.5 101.9 9.5 236.9 241.0 65.1 34.7 36.8 79.0 37.1 216.6 66.0 20.4 36.3 46.4 40.7 27.6 64.7 32.0 39.5 216.5 22.2 38.7 22.0 263.5 15.7 45.7 26.3 14.8 60.6 80.0 220.8 12.8 7.7 48.1 14.0 200.7 178.3 0.6 58.6 162.6 30.9 32.5 0.0 12.7 43.5 39.7 108.0 111.7 46.2 6.1 20.7 28.2 0.2 20.0 0.1 1.2 1.2 62.6 0.5 1.5 186.2 31.6 46.9 37.2 104.2 19.7 0.0 0.2 1.6 79.2 24.8 1.0 5.4 2.3 0.8 0.1 30.0 97.1 0.4 17.9 13.7 16.6 69.8 17.3 0.6 115.9 16.8 40.0 66.9 22.1 244.1 12.2 46.7 72.2 0.1 0.6 0.7 60.3 0.1 382.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.0 0.0 15.3 0.0 0.1 248.0 241.0 221.6 308.1 232.3 227.5 236.9 241.0 216.6 216.5 263.5 220.8 2.5 0.0 0.0 0.0 0.3 0.3 0.5 0.3 8.0 8.4 0.2 1.1 0.8 0.0 0.2 0.0 0.0 0.5 0.0 0.1 0.0 0.2 1.4 0.3 5.5 1.9 0.0 0.0 0.0 0.2 0.2 10.2 0.0 0.5 0.0 0.2 1.1 0.0 0.3 11.8 0.0 0.2 0.0 0.3 0.3 0.7 1.2 0.1 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.6 0.0 0.4 0.2 0.6 0.0 0.1 0.0 1.0 0.0 6.6 1.7 1.6 0.0 3.9 0.1 0.7 0.1 3.5 0.0 0.5 PDE3A CGI-PDE ENSG00000172572 "Phosphodiesterase 3A" Q14432 12 20368537-20688583 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 43.4" "Cell type enhanced" "Detected in many" "Astrocytes: 98.2;Bipolar cells: 38.4;Cardiomyocytes: 131.3;Horizontal cells: 52.2;Inhibitory neurons: 78.8;Smooth muscle cells: 49.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 8.6;HEL: 15.3;HeLa: 42.5;HUVEC TERT2: 7.4;SH-SY5Y: 17.9;U-138 MG: 11.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 18.8" "HPA014492, HPA074258" Approved Approved "Plasma membrane" NA NA 37000000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA014492: AB_1855120, HPA074258: " "unprognostic (2.59e-2)" "unprognostic (2.94e-2)" "unprognostic (1.25e-1)" "unprognostic (3.23e-1)" "unprognostic (2.27e-1)" "unprognostic (1.21e-1)" "unprognostic (3.50e-2)" "unprognostic (1.67e-2)" "unprognostic (8.14e-2)" "unprognostic (1.49e-1)" "unprognostic (4.25e-1)" "unprognostic (3.37e-1)" "prognostic unfavorable (1.72e-6)" "unprognostic (5.58e-2)" "unprognostic (5.94e-2)" "unprognostic (4.28e-2)" "unprognostic (2.76e-4)" 6.5 1.0 1.6 3.1 1.3 0.2 3.8 3.1 1.3 6.7 1.8 15.0 1.9 4.2 1.4 2.2 4.1 4.7 43.4 1.3 1.5 3.3 1.3 3.9 1.0 1.9 2.3 3.4 6.2 0.6 2.1 11.3 1.2 5.4 7.6 5.7 2.7 3.5 2.2 1.3 9.6 5.2 1.6 2.2 5.1 0.4 2.5 0.6 2.8 1.8 0.5 2.5 3.1 1.4 0.0 0.2 8.6 0.0 1.9 1.3 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 15.3 42.5 0.2 0.6 0.0 0.0 1.8 0.0 0.4 0.1 0.1 7.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 1.1 0.0 0.0 0.0 2.7 0.0 0.1 17.9 0.0 0.0 0.1 3.3 0.0 0.0 0.3 11.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 1.3 3.1 1.3 1.3 1.5 1.9 2.3 1.2 1.6 2.5 1.4 2.7 0.0 0.0 98.2 0.0 0.3 0.2 0.0 0.6 38.4 0.2 0.3 131.3 4.3 0.6 0.0 0.0 0.0 0.0 28.4 0.0 5.8 0.7 0.5 1.6 3.9 4.2 0.0 4.1 0.5 0.0 11.3 0.0 1.4 17.1 0.0 2.2 0.0 0.7 52.2 78.8 7.0 0.0 0.0 0.7 0.6 1.5 3.1 1.8 27.2 0.5 4.4 0.0 27.6 3.9 0.4 26.9 0.7 0.0 0.5 33.4 3.1 0.0 2.8 6.6 3.6 49.9 0.3 0.9 0.9 0.3 0.0 0.6 0.5 16.4 0.2 PHACTR1 "dJ257A7.2, KIAA1733, RPEL1" ENSG00000112137 "Phosphatase and actin regulator 1" Q9C0D0 6 12716554-13287843 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Protein phosphatase inhibitor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 38.0;brain: 52.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 1954.8;Inhibitory neurons: 523.7" "Cancer enriched" "Detected in many" 5 "melanoma: 10.2" "Group enriched" "Detected in many" 6 "basal ganglia: 52.1;cerebral cortex: 27.3;hippocampal formation: 14.8" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 37.8" "Group enriched" "Detected in many" 18 "B-cells: 13.6;dendritic cells: 37.8;granulocytes: 18.7" "Cell line enhanced" "Detected in many" "HMC-1: 74.6;SK-MEL-30: 79.5;U-266/70: 176.1;U-266/84: 133.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029755, HPA029756, HPA029757" Enhanced Uncertain "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA029755: AB_10600089, HPA029756: AB_10601852, HPA029757: AB_10669870" "unprognostic (7.86e-2)" "unprognostic (7.49e-2)" "unprognostic (2.74e-2)" "unprognostic (2.80e-1)" "unprognostic (1.59e-1)" "unprognostic (1.29e-1)" "unprognostic (7.72e-2)" "unprognostic (4.80e-2)" "unprognostic (1.10e-1)" "unprognostic (1.22e-1)" "unprognostic (3.67e-4)" "unprognostic (1.53e-1)" "prognostic unfavorable (5.48e-6)" "unprognostic (1.31e-1)" "unprognostic (1.43e-1)" "unprognostic (5.00e-2)" "unprognostic (1.16e-1)" 5.1 2.0 4.3 12.6 52.1 38.0 1.5 0.0 27.3 1.1 0.0 2.0 2.8 1.1 2.5 1.7 2.4 6.0 18.1 14.8 0.0 7.5 2.6 13.9 14.9 0.0 0.0 1.6 6.0 0.4 4.0 2.6 0.0 1.1 2.0 7.8 1.0 0.7 0.4 3.3 3.0 2.5 0.0 11.2 3.7 1.9 0.0 3.5 1.1 0.7 23.9 4.1 1.0 5.4 0.2 0.3 4.5 0.3 0.0 0.1 14.7 1.5 5.0 4.1 7.7 0.3 0.3 0.9 1.2 0.6 6.4 0.3 0.0 0.2 5.3 17.3 0.6 39.5 0.6 0.2 0.5 38.1 74.6 1.7 0.1 0.0 0.7 0.3 6.2 2.1 18.6 31.1 4.1 0.0 0.4 22.4 5.1 0.0 0.0 17.7 10.2 2.9 2.9 0.5 18.3 5.8 0.1 9.9 79.5 6.1 21.2 8.6 6.8 0.6 1.1 0.0 0.4 176.1 133.7 33.5 2.3 9.8 26.0 0.2 1.3 1.5 0.1 1.1 0.1 9.9 0.1 0.0 6.7 13.6 0.0 0.1 18.7 0.1 0.9 37.8 0.0 0.9 4.3 52.1 0.0 27.3 14.8 0.0 0.0 0.0 0.0 0.0 0.0 5.4 12.6 67.3 48.5 265.1 131.6 3.7 1.4 0.8 1.2 43.5 2.1 3.9 10.4 4.3 8.3 62.5 4.2 1.4 79.4 0.7 31.3 0.7 59.9 5.5 2.8 12.9 1.8 13.7 1954.8 2.9 2.3 8.6 0.5 15.0 81.2 2.7 13.6 1.1 83.1 180.0 523.7 0.2 0.0 138.2 91.5 79.8 4.7 188.5 48.0 114.3 20.5 28.4 6.2 186.5 247.8 0.8 0.2 6.4 59.6 1.0 0.3 1.0 5.1 14.0 0.0 4.0 4.3 2.0 4.8 2.1 3.1 1.9 8.6 6.6 1.0 0.8 PI3 "cementoin, ELAFIN, ESI, SKALP, WAP3, WFDC14" ENSG00000124102 "Peptidase inhibitor 3" P19957 20 45174902-45176544 "Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 2267.8;lymphoid tissue: 2103.1;vagina: 1595.8" "Group enriched" "Detected in many" 10 "Basal respiratory cells: 5354.5;Club cells: 2170.2" "Cancer enhanced" "Detected in many" "head and neck cancer: 2666.5" "Group enriched" "Detected in some" 22 "cerebral cortex: 12.0;pons: 7.3;thalamus: 19.0" "Immune cell enriched" "Detected in some" 1021 "neutrophil: 1763.3" "Lineage enriched" "Detected in single" 4377 "granulocytes: 1763.3" "Group enriched" "Detected in many" 5 "EFO-21: 89.3;HaCaT: 109.8;OE19: 103.7;PC-3: 189.9" "CAB009449, HPA017737" Enhanced Approved "Plasma membrane" "Secreted to blood" NA NA 1400000 "Cluster 1: Neutrophils - Mixed function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB009449: AB_2252354, HPA017737: AB_1848107" "prognostic favorable (6.94e-4)" "unprognostic (3.61e-2)" "unprognostic (1.00e-1)" "unprognostic (8.30e-2)" "unprognostic (7.34e-2)" "unprognostic (1.85e-1)" "unprognostic (3.20e-3)" "unprognostic (5.53e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (3.84e-6)" "prognostic unfavorable (6.89e-4)" "unprognostic (8.54e-3)" "prognostic unfavorable (1.94e-8)" "unprognostic (1.23e-1)" "unprognostic (7.38e-2)" "unprognostic (1.04e-2)" "unprognostic (5.91e-3)" 6.1 0.7 0.2 101.9 0.5 1.8 8.8 0.2 12.0 180.1 1.2 124.3 1.9 2.3 1.1 2267.8 4.8 56.6 1.7 0.2 0.4 1.5 3.3 32.5 0.4 0.3 0.3 0.7 1.6 0.2 2.8 1.1 7.3 11.7 43.3 0.0 460.8 3.5 0.6 78.6 42.3 7.5 0.3 20.0 9.0 0.5 19.0 90.6 0.8 1.9 2103.1 44.7 1595.8 0.3 0.7 0.3 0.0 0.0 0.0 0.0 0.1 0.0 7.7 0.4 0.0 3.1 2.1 1.4 89.3 0.0 1.1 109.8 0.0 23.2 0.1 1.2 0.0 0.5 6.3 0.9 0.0 0.7 0.0 0.0 21.7 17.8 1.9 0.0 0.1 0.0 1.3 0.2 0.0 0.0 0.1 0.1 0.2 103.7 189.9 0.0 1.0 0.0 21.9 0.4 0.0 0.0 15.7 2.1 0.1 0.0 0.0 0.0 0.8 1.0 10.9 0.3 0.9 0.3 1.8 0.4 14.3 0.7 0.1 0.3 0.4 1.7 0.0 0.3 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 1763.3 0.0 0.1 0.1 0.1 0.6 0.2 0.5 0.2 12.0 0.2 0.4 0.3 0.3 7.3 0.3 19.0 0.3 0.1 0.0 8.6 0.0 7.4 0.1 4.7 5354.5 0.0 0.0 39.4 8.4 0.2 8.6 2170.2 18.4 0.0 0.2 0.5 375.4 0.0 46.6 0.1 3.7 0.7 3.0 16.6 0.0 0.0 317.3 0.0 0.8 2.6 6.9 4.5 0.0 0.0 0.0 0.1 0.0 0.0 31.8 197.4 0.0 0.4 1.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 231.8 219.6 0.0 0.2 29.1 33.9 0.2 152.9 0.0 0.0 0.0 50.5 0.0 0.0 36.2 3.8 0.0 2.5 0.1 154.1 150.4 PI4K2A "DKFZP761G1923, PI4KII, PIK42A" ENSG00000155252 "Phosphatidylinositol 4-kinase type 2 alpha" Q9BTU6 10 97640686-97676434 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 38.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB030649, HPA076857" Approved Approved "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB030649: , HPA076857: AB_2686817" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "prognostic unfavorable (4.21e-5)" "unprognostic (1.80e-2)" "unprognostic (2.12e-1)" "unprognostic (1.75e-2)" "unprognostic (2.84e-3)" "unprognostic (1.60e-2)" "unprognostic (1.39e-3)" "unprognostic (1.38e-2)" "unprognostic (1.02e-2)" "unprognostic (1.65e-1)" "unprognostic (9.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.80e-1)" "unprognostic (1.45e-1)" "unprognostic (2.90e-1)" 12.0 25.7 15.5 10.0 15.1 24.1 9.3 15.1 18.9 12.6 13.4 10.7 9.8 12.7 13.0 20.7 9.6 14.0 14.2 15.5 17.8 12.6 15.0 14.2 11.2 20.2 18.8 10.0 8.4 16.6 15.8 18.0 22.0 10.9 8.7 12.9 10.5 10.4 12.7 17.4 10.8 13.0 15.8 14.6 9.4 10.8 17.3 9.8 9.5 13.0 10.6 14.5 12.7 15.2 28.7 21.3 17.2 30.7 36.0 25.8 13.8 28.0 61.5 43.3 45.7 19.4 27.7 10.4 16.2 35.8 31.8 27.1 19.3 55.9 35.8 12.6 16.4 9.3 14.6 17.7 34.5 8.4 12.7 27.3 46.9 45.4 80.1 47.4 22.4 19.9 14.7 16.5 30.4 14.6 18.4 6.4 11.1 14.7 19.8 8.6 17.8 10.3 29.7 26.6 5.8 18.9 23.9 5.9 35.5 24.0 16.4 13.2 25.0 20.6 15.2 24.6 22.1 14.6 18.4 16.9 38.1 5.0 6.8 0.0 1.2 0.0 1.3 0.8 1.0 1.4 0.5 1.1 1.3 0.6 0.4 0.9 0.4 0.7 0.6 0.6 1.2 0.6 15.5 15.1 15.1 18.9 15.5 17.8 20.2 18.8 22.0 15.8 17.3 15.2 4.9 3.2 5.4 9.8 12.0 13.4 4.5 6.5 8.0 14.7 10.7 8.9 10.4 10.0 4.3 5.5 12.5 14.0 12.5 8.6 3.9 4.9 2.4 6.8 15.4 6.9 3.0 8.2 10.9 4.9 6.4 12.0 7.1 7.6 1.3 5.7 3.6 9.9 38.1 11.8 10.9 4.0 6.1 15.0 24.7 2.2 4.4 19.0 10.6 12.2 15.0 8.0 18.6 5.5 6.0 7.2 0.8 9.1 9.4 5.8 9.0 7.3 4.8 15.1 6.6 11.9 8.0 11.0 6.1 6.3 14.3 27.1 9.7 12.4 3.6 7.8 PIGW "FLJ37433, Gwt1" ENSG00000277161 "Phosphatidylinositol glycan anchor biosynthesis class W" Q7Z7B1 17 36534987-36539310 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Acyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023499 Approved "Plasma membrane" No Yes "Cluster 27: Non-specific - Gene expression" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA023499: " "unprognostic (4.96e-3)" "unprognostic (3.84e-2)" "unprognostic (5.40e-3)" "unprognostic (7.39e-2)" "unprognostic (2.32e-1)" "unprognostic (7.71e-2)" "unprognostic (8.14e-3)" "unprognostic (1.05e-1)" "unprognostic (1.89e-1)" "unprognostic (4.62e-2)" "unprognostic (1.98e-1)" "unprognostic (3.29e-1)" "unprognostic (1.73e-2)" "unprognostic (1.41e-1)" "unprognostic (8.96e-2)" "unprognostic (1.08e-3)" "unprognostic (1.88e-1)" 4.5 3.8 1.0 3.9 1.1 2.7 3.9 1.4 1.5 3.2 1.8 4.3 2.6 4.2 2.0 7.4 3.4 1.9 3.7 1.0 1.5 6.5 6.5 3.7 3.8 1.5 1.2 2.5 4.7 2.6 4.0 2.0 1.5 3.3 3.6 1.8 5.0 1.3 8.2 5.8 4.3 2.6 1.1 4.4 4.5 2.8 1.4 2.1 4.1 3.4 3.5 3.6 4.3 1.3 10.8 15.2 9.0 9.2 4.9 4.2 15.0 11.6 6.2 12.2 9.3 11.7 12.2 19.9 3.8 7.9 14.9 15.7 16.5 8.0 16.1 11.3 23.3 14.7 7.3 11.0 3.8 32.2 17.2 5.2 9.6 12.5 5.4 2.5 7.9 6.3 26.9 9.5 8.9 10.1 16.4 11.2 16.5 7.5 13.0 15.3 24.0 18.8 7.6 11.6 20.7 16.7 21.0 8.6 9.3 8.4 27.8 4.7 10.4 21.7 29.1 20.8 26.1 8.8 32.8 22.0 5.2 18.0 19.6 0.8 1.7 0.3 2.0 2.7 2.8 1.5 2.6 2.1 3.5 2.9 3.2 3.1 0.4 2.6 3.5 2.1 1.6 2.2 1.0 1.1 1.4 1.5 1.0 1.5 1.5 1.2 1.5 1.1 1.4 1.3 3.6 3.2 3.1 1.6 4.6 3.4 9.5 4.6 12.5 2.2 4.3 2.9 1.6 10.0 4.2 0.0 0.0 6.1 5.4 2.9 7.9 6.8 0.2 2.4 3.6 4.7 1.2 12.6 2.0 6.4 6.7 3.8 5.1 2.7 0.0 2.3 1.1 6.0 4.5 3.3 2.6 4.0 0.0 3.3 2.2 0.6 2.8 3.5 0.0 0.0 3.1 4.2 1.0 1.5 2.5 7.1 3.6 2.2 4.9 10.2 1.0 4.9 2.8 3.1 0.0 3.7 3.6 3.4 7.4 9.4 6.8 4.1 3.1 3.5 5.6 5.3 PITPNM3 "ACKR6, CORD5, NIR1, RDGBA3" ENSG00000091622 "PITPNM family member 3" Q9BZ71 17 6451263-6556555 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 60.8" "Cell type enhanced" "Detected in many" "Excitatory neurons: 20.5;Hepatic stellate cells: 27.8;Inhibitory neurons: 24.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 23 "neutrophil: 2.2" "Lineage enriched" "Detected in single" 23 "granulocytes: 2.2" "Cell line enhanced" "Detected in some" "HaCaT: 17.7;HeLa: 14.8;hTCEpi: 50.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022432, HPA059005" Enhanced Approved "Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA022432: AB_2670936, HPA059005: AB_2683876" "unprognostic (2.97e-2)" "unprognostic (8.60e-3)" "unprognostic (1.45e-2)" "unprognostic (1.52e-1)" "unprognostic (2.69e-2)" "prognostic favorable (3.67e-6)" "unprognostic (1.25e-2)" "unprognostic (6.86e-2)" "unprognostic (3.66e-2)" "unprognostic (3.01e-2)" "unprognostic (2.99e-3)" "unprognostic (3.58e-2)" "unprognostic (2.41e-1)" "unprognostic (9.60e-2)" "unprognostic (1.61e-1)" "unprognostic (3.55e-1)" "unprognostic (2.63e-1)" 1.3 3.1 23.6 1.1 20.7 0.1 1.4 7.3 23.7 3.1 0.0 7.5 1.3 1.9 3.4 17.8 4.3 1.8 1.3 19.1 1.6 2.8 1.4 3.1 0.2 0.0 0.8 26.6 1.7 0.9 2.0 0.1 0.0 4.5 3.7 7.9 4.7 8.9 0.9 17.0 2.7 4.0 0.5 60.8 6.8 4.2 4.6 0.4 2.7 0.9 1.1 1.7 6.4 13.0 9.0 0.9 0.7 0.3 0.1 0.2 0.7 0.6 0.2 0.8 0.6 0.6 6.3 0.2 3.3 0.2 2.4 17.7 0.3 3.7 0.3 0.3 0.6 0.1 14.8 0.2 0.9 0.4 0.6 0.2 50.4 1.0 2.8 4.1 0.4 0.7 0.1 0.0 0.6 0.8 0.1 0.2 1.0 4.5 2.5 0.3 1.9 0.1 1.2 0.1 0.4 0.5 8.1 3.8 0.2 0.3 1.3 0.0 0.3 0.4 3.2 0.6 2.1 0.5 0.2 0.0 0.6 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 23.6 20.7 7.3 23.7 19.1 1.6 0.0 0.8 0.0 0.5 4.6 13.0 1.5 3.2 16.5 3.6 0.2 5.1 2.2 9.6 2.2 13.5 1.3 1.8 2.0 4.3 11.4 1.8 4.2 0.1 0.2 11.1 0.0 2.2 4.1 10.1 1.0 7.8 1.2 0.0 20.5 0.5 0.0 1.6 4.6 10.3 5.7 1.6 27.8 1.6 0.1 5.0 24.2 3.7 4.1 4.1 0.4 1.8 0.6 0.3 0.0 2.8 0.1 0.6 0.0 0.5 1.6 10.0 5.7 0.0 0.2 2.4 0.6 0.3 7.8 11.9 0.0 12.0 1.9 3.4 1.7 11.5 5.8 0.1 0.7 7.1 6.5 5.2 PLAAT5 "HRASLS5, HRLP5, iNAT, PLAAT-5" ENSG00000168004 "Phospholipase A and acyltransferase 5" Q96KN8 11 63461404-63491194 "Enzymes, Predicted intracellular proteins" "Acyltransferase, Hydrolase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adipose tissue: 16.5;pancreas: 13.6;testis: 53.4" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 1.6;Syncytiotrophoblasts: 1.0" "Cancer enhanced" "Detected in many" "breast cancer: 3.9" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 64 "basophil: 5.4;eosinophil: 16.4" "Lineage enriched" "Detected in single" 97 "granulocytes: 16.4" "Group enriched" "Detected in some" 5 "HAP1: 11.4;NB-4: 4.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA042493 Uncertain "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA042493: AB_10797499" "unprognostic (3.16e-1)" "unprognostic (3.45e-2)" "unprognostic (2.83e-3)" "unprognostic (4.24e-2)" "prognostic unfavorable (1.12e-4)" "unprognostic (7.11e-3)" "unprognostic (2.14e-1)" "unprognostic (6.66e-2)" "unprognostic (9.46e-2)" "unprognostic (8.89e-3)" "unprognostic (3.15e-2)" "unprognostic (7.33e-2)" "unprognostic (1.04e-5)" "unprognostic (1.52e-1)" "unprognostic (1.21e-2)" "unprognostic (2.57e-3)" "unprognostic (4.50e-4)" 16.5 0.2 1.2 0.3 0.9 0.1 3.3 0.7 0.8 0.1 0.0 0.7 0.2 0.5 0.2 0.8 0.9 0.6 0.6 1.0 1.3 0.1 0.0 0.6 0.1 1.5 0.5 0.6 13.6 0.0 0.0 0.0 1.0 0.4 0.2 0.5 0.8 1.3 0.1 0.2 0.3 1.4 1.1 0.1 0.5 53.4 0.8 0.0 0.1 0.1 0.0 0.5 0.1 3.2 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.4 0.0 16.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.7 0.8 1.0 1.3 1.5 0.5 1.0 1.1 0.8 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 PLAUR "CD87, UPAR, URKR" ENSG00000011422 "Plasminogen activator, urokinase receptor" Q03405 19 43646095-43670547 "Cancer-related genes, CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "bone marrow: 688.4" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 820.7;Langerhans cells: 1833.9;Macrophages: 864.3;Urothelial cells: 2274.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1172.3" "Group enriched" "Detected in all" 4 "granulocytes: 1172.3;monocytes: 550.7" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 311.7;U-251 MG: 413.1;U-87 MG: 346.9;WM-115: 346.5" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050843, CAB073533" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA 4100000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB073533: , HPA050843: AB_2681255" "unprognostic (9.28e-2)" "unprognostic (9.65e-3)" "unprognostic (1.39e-1)" "unprognostic (1.29e-3)" "unprognostic (3.59e-3)" "unprognostic (1.50e-2)" "unprognostic (2.18e-3)" "prognostic unfavorable (2.33e-5)" "unprognostic (8.08e-3)" "unprognostic (4.30e-2)" "unprognostic (2.29e-3)" "unprognostic (5.30e-2)" "prognostic unfavorable (7.83e-9)" "unprognostic (4.99e-2)" "unprognostic (1.66e-1)" "unprognostic (5.45e-2)" "unprognostic (9.33e-2)" 52.1 10.4 7.5 81.7 9.8 688.4 14.5 11.2 32.4 30.9 10.3 26.7 10.0 30.2 4.8 11.6 22.8 78.1 23.0 8.1 10.4 18.2 19.8 69.5 10.6 12.2 9.8 14.9 13.6 5.4 9.1 35.9 13.3 11.5 20.1 2.8 21.7 5.8 3.6 7.8 10.6 26.2 9.7 20.4 28.4 3.1 24.8 10.2 9.5 4.7 8.6 109.7 15.8 13.8 83.9 31.0 26.1 1.9 23.4 83.3 16.2 180.7 189.6 114.6 141.4 2.4 95.1 2.4 43.0 116.9 66.8 35.2 7.0 46.4 127.9 5.3 5.3 15.8 44.7 3.9 30.6 18.8 195.2 87.4 9.0 311.7 46.5 160.6 129.0 19.1 16.4 2.2 107.7 6.1 21.0 55.3 8.7 156.1 64.7 24.0 17.4 5.6 35.9 3.8 1.3 22.2 82.0 17.4 25.0 12.6 3.2 59.4 129.7 230.0 121.1 109.8 413.1 3.0 9.0 0.6 346.9 36.0 346.5 87.7 476.5 745.5 6.8 427.9 8.3 2.7 8.9 5.7 213.6 1.4 3.2 4.0 1172.3 6.7 550.7 69.3 3.6 253.9 7.5 9.8 11.2 32.4 8.1 10.4 12.2 9.8 13.3 9.7 24.8 13.8 23.1 73.7 76.6 2.3 15.5 105.2 820.7 274.2 72.3 0.7 45.8 22.5 4.5 24.3 151.9 20.2 0.0 6.5 17.4 314.5 1.9 219.3 0.9 188.1 68.0 64.9 14.8 5.2 2.5 106.5 58.8 145.4 156.0 519.1 305.2 4.2 19.2 1.7 428.9 10.1 3.3 85.3 22.4 155.4 1833.9 2.0 6.8 864.3 72.9 5.6 52.1 1.2 4.1 1.5 0.9 558.8 435.5 4.1 14.5 479.4 12.7 2.7 52.7 0.7 6.6 38.5 90.0 1.2 4.7 202.6 63.1 13.1 33.2 3.1 29.3 2274.4 PLCB1 "KIAA0581, PLC-I, PLC154" ENSG00000182621 "Phospholipase C beta 1" Q9NQ66 20 8077251-8968360 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.3" "Cell type enhanced" "Detected in many" "Astrocytes: 563.5;Excitatory neurons: 2569.1;Inhibitory neurons: 1774.0;Oligodendrocyte precursor cells: 783.1" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 74.3" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 45.5;Hep G2: 68.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004275, CAB005334, HPA034743, HPA057910" Enhanced Approved "Plasma membrane" NA NA 6600 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "CAB004275: AB_628118, CAB005334: AB_632196, HPA034743: AB_2674311, HPA057910: AB_2683552" "unprognostic (2.32e-1)" "unprognostic (1.02e-1)" "unprognostic (6.63e-2)" "unprognostic (9.77e-2)" "unprognostic (9.87e-2)" "unprognostic (2.37e-1)" "unprognostic (1.27e-4)" "unprognostic (1.13e-1)" "unprognostic (3.16e-2)" "unprognostic (1.91e-1)" "unprognostic (7.12e-3)" "unprognostic (6.57e-2)" "unprognostic (2.87e-3)" "unprognostic (3.20e-2)" "unprognostic (4.41e-2)" "unprognostic (1.71e-2)" "unprognostic (2.12e-1)" 9.3 8.9 11.7 5.7 52.3 4.8 7.6 0.0 74.3 8.2 0.0 18.1 7.2 9.3 3.5 5.4 9.6 8.5 11.7 17.4 0.0 13.2 4.3 5.0 1.8 0.0 0.1 3.7 14.7 44.3 4.3 19.6 0.0 13.4 4.1 7.1 29.0 18.8 14.4 2.6 5.7 8.1 0.0 3.6 8.0 3.0 9.8 6.8 3.8 11.0 0.9 15.9 6.7 23.8 0.2 1.2 4.8 0.3 8.7 16.1 6.3 20.2 13.1 5.2 3.1 45.5 5.0 2.2 8.2 3.9 0.3 0.0 3.7 0.0 3.8 0.0 4.4 1.0 3.5 68.7 2.2 1.1 0.7 1.1 0.8 7.1 0.0 6.5 10.6 13.0 7.1 26.0 0.1 6.2 1.0 3.3 15.0 10.6 6.6 14.7 0.0 12.1 4.0 16.8 16.9 7.2 0.1 4.1 0.9 17.1 19.9 6.6 1.9 16.8 7.5 1.3 12.7 19.4 24.5 33.9 8.6 12.6 29.5 0.3 1.3 1.2 1.4 0.3 2.0 0.1 0.4 0.5 0.1 0.2 0.2 0.4 0.8 1.1 0.1 0.3 0.1 0.2 11.7 52.3 0.0 74.3 17.4 0.0 0.0 0.1 0.0 0.0 9.8 23.8 74.8 0.0 3.4 563.5 1.1 1.9 20.8 2.3 8.0 7.6 8.1 23.2 26.9 7.2 2.6 16.5 0.0 2.4 16.8 1.3 33.2 1.2 9.9 42.1 5.1 54.6 0.0 6.5 2569.1 13.4 2.8 25.8 3.6 83.6 1.3 0.2 26.4 2.8 0.8 1.7 1774.0 2.1 0.0 8.2 1.2 4.3 3.4 9.1 7.2 211.7 12.2 18.2 15.5 783.1 34.8 1.8 0.5 3.8 6.1 20.2 0.1 9.4 9.9 4.1 0.0 7.4 13.3 4.7 5.6 2.5 1.7 1.8 15.4 1.1 1.2 18.9 PLCD3 ENSG00000161714 "Phospholipase C delta 3" Q8N3E9 17 45108959-45133354 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 85.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 195.8;Paneth cells: 104.7;Urothelial cells: 88.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "OE19: 109.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025711, HPA053665" Approved Approved "Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA025711: AB_1855320, HPA053665: AB_2732580" "unprognostic (3.58e-2)" "unprognostic (1.66e-1)" "unprognostic (2.77e-2)" "unprognostic (1.27e-2)" "unprognostic (2.66e-1)" "unprognostic (4.14e-3)" "unprognostic (8.13e-3)" "prognostic unfavorable (2.89e-6)" "unprognostic (2.96e-1)" "unprognostic (9.53e-2)" "unprognostic (1.34e-3)" "unprognostic (6.21e-2)" "unprognostic (3.18e-2)" "unprognostic (2.07e-1)" "unprognostic (1.62e-1)" "prognostic favorable (4.28e-4)" "unprognostic (3.34e-3)" 13.5 34.3 42.2 5.1 49.7 2.0 11.7 50.5 36.0 12.4 27.9 34.2 2.5 13.2 1.5 14.7 10.1 6.4 34.1 33.8 42.5 9.6 1.4 7.7 1.0 69.8 50.5 18.9 2.7 1.3 7.6 5.8 46.4 13.0 15.3 14.4 10.8 5.4 85.7 20.6 6.5 5.1 62.8 2.0 21.0 10.8 59.4 0.9 5.3 56.5 1.5 30.4 11.9 54.0 23.1 56.2 4.1 8.1 5.9 12.8 28.0 12.3 27.3 11.2 10.5 13.7 40.9 0.8 43.5 29.0 9.2 51.9 6.3 53.1 4.4 11.6 21.0 0.9 62.6 18.1 30.3 1.3 3.2 13.7 21.0 10.4 13.7 28.5 7.0 2.5 5.0 1.7 12.1 36.2 3.7 5.4 4.9 109.9 55.0 8.1 9.2 1.5 35.8 45.1 1.1 7.2 13.3 22.1 12.5 8.5 47.0 2.5 14.3 6.9 37.9 9.3 14.8 2.1 2.6 1.8 11.4 1.5 5.7 0.7 0.3 0.5 0.1 0.3 0.1 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.5 0.2 0.0 0.1 0.1 0.1 42.2 49.7 50.5 36.0 33.8 42.5 69.8 50.5 46.4 62.8 59.4 54.0 8.7 12.8 1.3 22.9 1.0 7.6 16.3 12.2 21.1 29.8 6.8 9.3 26.9 14.3 4.9 7.3 25.0 3.9 0.9 195.8 1.9 6.7 15.8 3.3 12.7 9.0 4.9 0.0 1.3 3.5 13.1 10.6 29.6 9.6 1.3 6.5 10.4 0.7 1.6 6.7 3.7 15.1 4.1 1.4 1.9 5.5 19.9 1.6 3.6 1.0 1.2 8.9 0.0 0.0 0.1 30.0 104.7 33.1 1.1 28.7 4.2 2.0 2.7 40.0 6.6 16.8 4.9 2.3 7.6 3.8 5.7 7.3 1.1 7.0 46.2 88.6 PLPP1 "LPP1, PAP-2a, PPAP2A" ENSG00000067113 "Phospholipid phosphatase 1" O14494 5 55424854-55534969 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 359.1;Endometrial stromal cells: 206.7;Hepatic stellate cells: 267.0;Leydig cells: 219.3;Prostatic glandular cells: 182.0" "Cancer enhanced" "Detected in all" "prostate cancer: 200.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC diff: 445.7;fHDF/TERT166: 142.8;HMC-1: 235.8;HSkMC: 171.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB033331, HPA047815" Enhanced Supported "Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB033331: AB_2168044, HPA047815: AB_2680164" "unprognostic (1.22e-1)" "unprognostic (1.54e-1)" "unprognostic (1.74e-1)" "unprognostic (1.55e-2)" "unprognostic (2.52e-1)" "unprognostic (1.36e-1)" "prognostic favorable (6.06e-4)" "unprognostic (2.81e-1)" "unprognostic (2.20e-1)" "unprognostic (4.05e-3)" "unprognostic (2.43e-2)" "unprognostic (1.05e-1)" "unprognostic (4.37e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (3.94e-2)" "unprognostic (1.66e-1)" "unprognostic (3.11e-2)" 172.3 78.1 51.5 42.3 59.9 0.9 140.7 63.7 59.4 88.7 59.6 118.3 47.4 119.5 39.8 42.4 73.4 167.5 117.1 49.9 56.8 104.0 67.7 56.2 32.2 62.1 56.2 29.4 35.6 49.0 27.8 37.6 64.2 254.1 65.8 9.7 32.9 61.3 70.0 57.9 79.1 108.9 62.5 31.1 70.9 21.0 58.6 15.8 112.9 81.5 24.2 128.8 63.8 72.9 9.8 24.4 7.0 14.2 445.7 51.8 9.6 21.8 61.4 11.9 27.9 16.7 17.7 10.2 20.0 142.8 31.9 6.5 25.2 12.6 13.5 6.8 20.1 1.1 9.6 21.3 70.5 2.5 235.8 171.3 25.7 17.6 10.9 23.3 19.9 9.1 0.2 27.0 24.1 6.0 6.8 5.5 15.5 1.1 20.0 2.0 11.7 0.9 46.3 79.8 8.4 5.8 21.5 4.2 13.4 28.8 15.6 1.6 24.0 4.0 6.9 17.8 15.5 16.6 7.4 11.8 15.7 1.3 19.5 0.0 0.4 4.0 1.6 0.5 1.7 6.7 5.3 3.4 2.0 3.3 9.5 7.7 0.3 3.0 0.9 15.0 2.6 1.8 51.5 59.9 63.7 59.4 49.9 56.8 62.1 56.2 64.2 62.5 58.6 72.9 359.1 6.4 9.4 0.0 9.8 0.0 51.0 0.0 10.2 4.0 8.4 45.7 0.0 21.5 5.6 29.5 2.1 3.3 5.4 61.0 5.9 25.2 44.4 10.7 206.7 112.3 1.2 5.7 0.0 28.5 11.1 115.5 11.2 18.5 27.8 4.0 267.0 48.3 12.8 1.7 0.0 20.2 0.0 12.0 0.0 21.0 219.3 8.1 0.0 0.0 4.5 16.6 1.0 0.0 0.0 30.0 24.6 88.4 13.0 182.0 49.4 29.3 2.2 5.6 59.2 89.7 49.7 54.4 17.7 10.0 0.0 4.9 11.3 3.1 12.1 42.8 PLPP2 "LPP2, PAP-2c, PPAP2C" ENSG00000141934 "Phospholipid phosphatase 2" O43688 19 281040-291403 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 204.5;Ductal cells: 352.1;Proximal enterocytes: 209.8;Rod photoreceptor cells: 234.9;Urothelial cells: 205.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 3.2;MAIT T-cell: 6.6" "Lineage enriched" "Detected in single" 41 "T-cells: 6.6" "Cell line enhanced" "Detected in many" "A549: 144.1;CAPAN-2: 154.6;OE19: 255.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA055540, HPA058428" Uncertain Supported "Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA055540: AB_2682839, HPA058428: " "prognostic unfavorable (4.55e-4)" "unprognostic (8.91e-3)" "unprognostic (1.06e-1)" "prognostic favorable (3.21e-8)" "unprognostic (2.95e-1)" "unprognostic (1.36e-1)" "unprognostic (3.83e-3)" "unprognostic (5.48e-2)" "unprognostic (1.59e-1)" "unprognostic (5.67e-2)" "unprognostic (1.18e-3)" "unprognostic (3.85e-1)" "unprognostic (3.53e-3)" "unprognostic (1.06e-2)" "unprognostic (1.71e-1)" "unprognostic (1.30e-3)" "unprognostic (1.36e-3)" 4.8 13.2 37.7 8.5 61.6 0.0 36.9 57.1 50.0 63.4 26.2 40.5 62.7 16.8 8.4 27.2 81.8 52.4 1.7 38.8 43.5 11.5 3.7 8.3 1.4 57.3 53.6 2.7 37.3 19.5 11.8 3.6 56.2 31.7 32.1 29.6 105.7 32.9 0.6 53.2 51.0 6.4 44.8 4.7 50.3 7.6 49.2 5.2 5.7 0.5 6.0 36.5 14.2 83.9 85.5 144.1 2.1 0.1 0.0 0.3 0.2 8.2 0.0 25.3 18.9 41.7 154.6 0.0 88.3 11.9 0.1 45.3 0.0 17.6 11.1 0.8 2.6 0.0 55.9 0.0 28.6 0.0 5.5 5.2 7.6 12.7 16.7 53.4 4.2 0.0 0.7 0.1 0.0 98.5 0.4 0.1 61.5 255.8 0.0 0.0 0.0 2.4 62.1 13.7 17.4 40.9 23.3 38.3 60.3 5.8 50.0 2.5 4.5 55.7 36.5 0.5 61.9 0.8 101.7 70.4 15.5 0.0 46.9 0.0 0.0 0.0 3.2 0.0 6.6 0.0 1.3 1.6 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 37.7 61.6 57.1 50.0 38.8 43.5 57.3 53.6 56.2 44.8 49.2 83.9 17.0 6.4 7.5 0.0 1.5 0.0 134.2 0.0 8.0 19.7 137.1 149.9 0.0 204.5 35.3 22.0 10.4 0.5 2.7 77.0 3.9 352.1 0.3 115.2 9.2 15.2 8.5 0.0 0.0 139.5 15.1 3.0 91.3 90.1 1.3 0.0 0.0 0.5 0.9 16.8 0.0 38.8 0.0 1.0 0.0 1.6 0.0 1.9 0.0 0.0 2.6 21.7 0.0 0.0 0.0 128.8 85.2 0.0 1.6 97.4 209.8 1.4 91.1 234.9 0.0 0.8 2.7 0.6 35.1 20.3 0.0 0.8 3.5 0.1 87.2 205.8 PLXNA4 "DKFZp434G0625PRO34003, FAYV2820, KIAA1550, PLXNA4A, PLXNA4B" ENSG00000221866 "Plexin A4" Q9HCM2 7 132123332-132648688 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 13.8;brain: 29.1" "Group enriched" "Detected in many" 4 "Excitatory neurons: 235.3;Inhibitory neurons: 261.3" "Cancer enhanced" "Detected in many" "glioma: 3.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 29.1;hippocampal formation: 26.0" "Immune cell enriched" "Detected in single" 5 "plasmacytoid DC: 2.6" "Lineage enriched" "Detected in single" 5 "dendritic cells: 2.6" "Cell line enhanced" "Detected in some" "ASC diff: 25.2;HMC-1: 17.1;hTERT-RPE1: 22.1;RH-30: 18.5;TIME: 57.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029919, HPA052141, HPA075592" Approved Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA029919: AB_10671093, HPA052141: AB_2681745, HPA075592: AB_2732297" "unprognostic (2.05e-2)" "unprognostic (3.59e-2)" "unprognostic (2.08e-2)" "prognostic unfavorable (1.61e-6)" "unprognostic (5.76e-2)" "unprognostic (1.21e-2)" "unprognostic (1.28e-2)" "unprognostic (2.43e-2)" "unprognostic (2.19e-1)" "unprognostic (7.99e-2)" "unprognostic (7.64e-2)" "unprognostic (1.14e-1)" "unprognostic (1.69e-5)" "unprognostic (1.67e-1)" "unprognostic (2.28e-1)" "unprognostic (5.90e-2)" "unprognostic (1.42e-3)" 13.8 2.4 4.2 1.6 5.6 0.3 7.6 0.1 29.1 8.4 0.0 1.5 0.4 1.5 0.2 3.8 2.0 1.9 3.9 26.0 1.3 0.7 0.3 1.2 1.0 2.3 0.1 3.6 0.4 0.1 1.0 3.5 1.8 0.5 0.7 4.8 0.4 0.9 0.7 2.2 0.8 2.6 0.9 1.5 1.6 1.1 1.6 0.2 1.5 3.1 0.3 1.0 0.7 4.4 0.0 0.1 0.2 0.0 25.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.1 0.0 17.1 0.2 0.0 0.1 0.0 22.1 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.6 0.0 0.0 0.0 18.5 2.0 0.0 0.0 0.4 9.6 0.0 0.0 0.0 0.2 0.0 0.0 57.6 5.7 0.2 1.3 0.5 0.0 0.0 0.0 5.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.6 0.0 0.0 4.2 5.6 0.1 29.1 26.0 1.3 2.3 0.1 1.8 0.9 1.6 4.4 2.5 0.0 0.0 5.2 0.6 0.6 0.2 0.0 0.0 22.4 2.2 0.1 10.9 0.0 0.0 12.9 16.7 0.1 17.4 0.0 0.0 0.0 14.0 2.1 3.0 2.7 1.2 0.0 235.3 0.0 0.1 7.4 1.1 5.0 1.3 1.6 5.0 0.2 0.1 0.0 261.3 0.1 0.0 0.0 1.1 9.8 14.0 0.7 7.2 10.3 0.0 11.3 2.1 51.8 3.7 0.8 0.0 7.2 0.7 0.1 0.0 0.5 0.0 1.5 0.0 0.7 1.1 0.2 0.3 0.1 1.3 0.0 1.7 0.4 0.1 0.4 PPFIBP1 "hSGT2, hSgt2p, L2, SGT2" ENSG00000110841 "PPFIA binding protein 1" Q86W92 12 27523431-27695564 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 201.3;Endothelial cells: 189.5;Excitatory neurons: 206.1;Oligodendrocytes: 202.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "naive B-cell: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001924, HPA071162" Uncertain Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001924: AB_1079665, HPA071162: " "unprognostic (5.27e-2)" "unprognostic (5.71e-2)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.29e-4)" "unprognostic (4.73e-2)" "unprognostic (6.94e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (5.11e-4)" "unprognostic (7.33e-2)" "unprognostic (3.84e-2)" "prognostic unfavorable (2.56e-4)" "unprognostic (1.92e-2)" "prognostic favorable (5.11e-7)" "unprognostic (8.54e-2)" "unprognostic (7.54e-2)" "unprognostic (2.64e-1)" "unprognostic (4.09e-2)" 32.4 27.0 22.5 13.7 33.6 3.3 37.9 0.3 29.5 24.0 18.3 25.0 11.9 27.7 11.4 28.6 26.6 20.1 77.0 29.0 10.0 36.3 26.7 39.6 9.3 7.0 14.9 85.2 21.3 17.1 19.6 60.2 11.2 24.7 18.2 5.1 21.6 29.3 25.9 30.4 15.0 31.3 5.9 29.9 25.5 11.9 31.6 18.5 39.0 44.3 10.5 24.4 29.5 22.9 18.8 37.1 29.7 25.5 48.4 133.3 52.9 67.0 75.2 38.6 55.4 98.0 55.9 14.2 75.6 135.7 51.5 46.0 16.3 61.0 69.1 32.3 9.0 31.3 28.3 14.6 21.0 9.8 16.9 104.8 41.3 112.1 114.0 75.2 134.0 18.9 16.7 13.9 138.5 14.4 9.1 2.8 53.4 26.8 28.5 14.6 74.0 5.5 56.6 41.0 2.4 12.1 33.4 17.6 91.3 206.5 22.7 14.3 131.3 107.7 36.0 59.8 68.8 0.2 0.4 1.2 119.7 13.7 173.7 0.9 0.2 0.1 0.3 0.0 0.6 0.3 0.5 0.3 0.3 2.7 0.5 0.5 0.6 0.1 0.1 0.9 0.8 0.2 22.5 33.6 0.3 29.5 29.0 10.0 7.0 14.9 11.2 5.9 31.6 22.9 201.3 99.3 19.8 7.5 9.4 41.0 76.5 42.8 68.3 15.5 19.6 40.3 164.0 10.0 18.3 80.9 4.2 37.2 2.5 8.0 11.7 42.2 3.5 40.2 12.7 189.5 18.6 8.6 206.1 24.8 23.2 74.6 46.9 73.3 3.8 132.8 157.8 14.0 8.9 45.4 68.4 15.9 10.2 16.7 30.9 5.4 21.1 6.2 62.2 174.3 3.1 6.3 0.0 116.6 202.9 33.9 19.7 42.2 4.6 45.0 8.6 48.7 9.0 1.8 19.7 71.7 78.9 2.4 8.6 48.2 27.6 91.9 5.9 25.4 12.5 84.5 PPP1R16A "MGC14333, MYPT3" ENSG00000160972 "Protein phosphatase 1 regulatory subunit 16A" Q96I34 8 144477969-144502121 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 208.9;Proximal enterocytes: 440.8;Proximal tubular cells: 404.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "MCF7: 49.9" "Low region specificity" "Detected in all" HPA023755 Uncertain Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 43: Testis - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA023755: AB_1854268" "unprognostic (9.63e-2)" "unprognostic (4.51e-2)" "unprognostic (5.45e-3)" "unprognostic (3.11e-1)" "unprognostic (5.60e-2)" "unprognostic (3.75e-2)" "unprognostic (4.64e-3)" "unprognostic (2.65e-1)" "unprognostic (3.68e-2)" "unprognostic (2.20e-2)" "unprognostic (1.52e-2)" "unprognostic (1.35e-1)" "unprognostic (1.05e-1)" "unprognostic (1.29e-2)" "unprognostic (1.03e-1)" "unprognostic (9.45e-2)" "unprognostic (2.79e-2)" 6.1 15.0 10.2 4.7 8.6 3.8 8.2 4.3 15.0 10.5 16.7 25.1 27.1 10.5 1.6 9.8 18.9 3.1 9.6 12.9 8.9 26.7 23.5 10.8 2.9 10.2 10.4 7.9 17.7 7.4 36.9 1.7 7.1 15.5 2.4 2.9 11.6 5.6 6.3 9.0 24.6 1.6 8.1 8.0 14.1 33.3 10.3 2.4 27.0 1.0 1.0 9.1 6.7 5.1 30.4 24.3 3.9 15.1 1.6 2.7 19.3 8.2 5.1 6.3 5.1 6.4 21.2 5.0 21.1 3.0 5.6 19.8 2.0 6.7 1.0 10.3 11.9 6.0 26.4 6.8 4.7 4.3 7.9 2.7 8.9 7.3 2.1 4.1 4.5 8.2 24.0 6.1 2.3 49.9 15.3 19.9 7.4 15.6 30.3 15.9 1.9 10.1 5.7 10.0 12.5 23.9 14.9 13.7 13.0 1.0 32.3 9.1 7.7 7.1 33.2 19.8 15.8 4.0 4.3 1.8 22.8 8.3 6.5 0.0 0.8 0.0 1.0 1.2 0.9 0.8 0.8 1.0 1.2 0.1 0.5 1.1 0.2 0.2 1.7 0.7 0.6 0.8 10.2 8.6 4.3 15.0 12.9 8.9 10.2 10.4 7.1 8.1 10.3 5.1 7.9 3.2 15.4 28.1 6.2 43.2 36.2 47.6 54.1 25.0 78.3 82.0 85.8 157.3 24.6 40.5 14.6 7.2 6.0 135.9 121.3 33.7 12.6 43.8 15.6 13.3 51.6 6.1 7.8 41.6 24.3 13.3 70.3 24.2 3.8 16.4 12.8 208.9 6.1 30.3 7.6 98.1 26.4 7.0 27.1 14.4 22.7 9.8 8.8 5.6 3.8 102.8 5.2 6.6 2.8 29.3 109.8 15.4 5.9 40.0 440.8 404.2 59.8 50.9 6.6 17.2 17.3 52.9 28.7 77.8 61.8 6.7 7.1 69.2 116.0 28.3 PPP1R9A "FLJ20068, KIAA1222, Neurabin-I" ENSG00000158528 "Protein phosphatase 1 regulatory subunit 9A" Q9ULJ8 7 94907202-95296415 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 20.1" "Cell type enhanced" "Detected in many" "Astrocytes: 294.1;Excitatory neurons: 262.8;Inhibitory neurons: 201.5;Oligodendrocyte precursor cells: 593.1;Oligodendrocytes: 308.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "basophil: 6.8;NK-cell: 10.3" "Group enriched" "Detected in many" 9 "granulocytes: 6.8;NK-cells: 10.3" "Cell line enhanced" "Detected in many" "HAP1: 12.2;RH-30: 11.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027726, HPA075591" Approved Approved "Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 36: HEL - Hemostasis" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA027726: AB_1855653, HPA075591: AB_2732296" "unprognostic (1.05e-1)" "unprognostic (6.59e-2)" "unprognostic (5.90e-2)" "unprognostic (1.63e-2)" "unprognostic (1.35e-1)" "unprognostic (1.12e-1)" "unprognostic (8.62e-2)" "unprognostic (6.19e-2)" "unprognostic (1.45e-1)" "prognostic favorable (7.17e-4)" "unprognostic (2.26e-2)" "unprognostic (1.89e-1)" "prognostic favorable (8.63e-6)" "unprognostic (2.74e-1)" "unprognostic (4.85e-2)" "unprognostic (8.47e-2)" "unprognostic (8.79e-3)" 1.7 7.0 13.0 0.9 20.1 0.2 4.9 6.0 14.5 2.7 0.3 8.2 1.7 3.0 4.9 1.6 5.7 2.4 5.2 14.4 7.5 4.7 0.4 3.7 0.3 5.9 6.9 3.3 8.8 6.7 4.6 2.5 8.0 2.3 3.8 18.5 9.6 2.8 4.9 0.5 2.2 2.2 6.6 1.8 4.9 6.7 10.2 0.5 6.6 4.9 0.3 2.6 0.5 13.9 0.0 11.0 6.6 7.6 0.0 0.0 5.3 0.5 0.1 1.0 0.8 6.1 3.7 0.0 9.0 0.5 0.6 0.0 12.2 0.0 1.2 0.0 4.5 11.4 4.5 7.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.8 4.8 0.1 0.0 5.5 4.9 1.8 0.0 11.8 0.0 10.7 9.2 7.3 7.4 0.0 0.9 1.4 4.0 2.1 0.0 0.0 0.1 4.4 0.1 4.0 7.3 11.5 0.0 0.2 0.0 0.9 6.8 0.0 0.4 0.0 0.0 0.2 0.7 0.0 0.0 0.0 1.0 0.0 0.0 0.0 10.3 0.1 0.3 0.0 0.1 13.0 20.1 6.0 14.5 14.4 7.5 5.9 6.9 8.0 6.6 10.2 13.9 4.5 41.7 66.6 294.1 2.4 0.4 0.9 0.0 0.6 58.2 24.4 12.2 127.7 18.6 16.5 47.8 56.3 21.6 3.3 15.7 3.9 25.1 17.9 40.3 4.5 6.8 38.9 2.5 262.8 7.0 3.1 9.4 21.4 57.1 5.7 39.5 7.9 1.5 1.7 1.7 201.5 15.0 4.1 0.6 0.3 15.3 2.5 0.8 7.2 41.2 0.0 46.9 3.1 593.1 308.4 6.6 14.4 0.7 2.7 4.8 1.8 9.6 20.6 88.9 0.0 118.4 9.2 25.1 12.6 0.5 0.9 33.1 1.7 22.9 15.7 2.6 PRRT2 "DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC" ENSG00000167371 "Proline rich transmembrane protein 2" Q7Z6L0 16 29811382-29815892 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Dystonia, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 124.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.3;Cone photoreceptor cells: 31.3;Leydig cells: 36.1;Peritubular cells: 40.3;Rod photoreceptor cells: 37.1" "Cancer enhanced" "Detected in many" "glioma: 5.8" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 7 "NK-cell: 3.2" "Lineage enriched" "Detected in single" 7 "NK-cells: 3.2" "Cell line enhanced" "Detected in many" "AF22: 24.1;HeLa: 13.8;hTERT-RPE1: 14.0;REH: 17.6;U-138 MG: 14.5" "HPA014447, HPA019203, HPA048045" Enhanced Supported "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA014447: AB_1855786, HPA019203: AB_2670097, HPA048045: " "unprognostic (7.60e-3)" "unprognostic (3.00e-1)" "unprognostic (8.32e-3)" "unprognostic (4.34e-2)" "unprognostic (3.72e-2)" "unprognostic (1.19e-3)" "unprognostic (2.85e-1)" "unprognostic (1.23e-1)" "unprognostic (9.30e-2)" "unprognostic (1.93e-1)" "unprognostic (4.45e-2)" "unprognostic (3.26e-2)" "unprognostic (3.43e-8)" "unprognostic (1.22e-1)" "unprognostic (1.17e-1)" "unprognostic (5.12e-2)" "unprognostic (2.44e-2)" 13.4 10.5 32.9 2.4 40.4 0.3 10.8 70.7 70.5 79.4 0.0 33.9 5.3 39.5 8.6 6.7 47.0 10.9 15.6 46.0 20.1 8.7 2.4 12.9 3.3 15.6 8.0 124.3 4.7 4.3 85.6 7.0 16.2 39.1 2.3 19.8 5.4 13.9 4.5 5.0 14.5 10.4 24.5 1.7 12.4 14.6 29.2 0.5 10.6 1.8 1.0 34.1 51.0 34.0 0.1 1.5 24.1 8.6 1.2 4.2 0.5 2.5 4.1 1.0 0.8 1.1 1.5 0.2 0.3 4.4 0.5 1.6 3.4 0.2 0.4 4.1 1.4 1.7 13.8 1.6 0.3 0.0 0.3 4.1 0.1 1.9 0.1 14.0 1.0 0.7 0.2 1.5 0.2 3.1 0.6 0.5 5.0 0.1 1.1 17.6 0.9 0.4 0.2 0.8 4.1 4.3 0.2 2.1 0.5 3.5 7.6 0.0 1.3 14.5 5.2 0.7 1.4 3.7 0.5 0.2 5.3 0.2 0.5 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.1 3.2 0.1 0.0 0.0 0.1 32.9 40.4 70.7 70.5 46.0 20.1 15.6 8.0 16.2 24.5 29.2 34.0 2.3 3.2 0.0 22.9 0.9 1.1 1.4 1.7 0.6 82.3 1.6 1.7 0.8 1.5 1.2 0.0 31.3 1.9 1.9 9.5 1.9 1.1 2.0 4.4 10.4 5.0 6.1 0.0 24.4 1.5 0.8 11.4 2.0 1.6 0.0 1.7 3.3 0.1 0.4 20.2 19.5 4.2 2.0 0.0 2.4 9.8 36.1 0.5 0.0 5.6 0.6 5.7 1.0 8.5 1.6 3.0 9.0 40.3 0.7 1.8 15.2 1.0 5.6 37.1 6.6 2.9 11.7 2.4 3.1 0.4 0.4 2.6 2.7 0.6 2.5 1.3 PSCA ENSG00000167653 "Prostate stem cell antigen" O43653 8 142670308-142682725 "Cancer-related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "stomach 1: 3019.3" "Cell type enriched" "Detected in many" 4 "Gastric mucus-secreting cells: 5332.3" "Cancer enriched" "Detected in many" 6 "urothelial cancer: 785.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 22.4;HeLa: 45.7;OE19: 17.6;RT4: 61.7" "Not detected" "Not detected" "Region enriched" "Detected in many" 8 "spinal cord: 38.2" "HPA030783, HPA056418" Approved Supported "Plasma membrane" NA NA 18000 "Cluster 4: Stomach - Digestion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA030783: AB_2673611, HPA056418: AB_2683123" "unprognostic (1.21e-3)" "unprognostic (1.76e-3)" "unprognostic (3.20e-1)" "unprognostic (2.24e-1)" "unprognostic (1.77e-2)" "unprognostic (7.57e-2)" "unprognostic (1.93e-2)" "unprognostic (7.81e-3)" "unprognostic (8.25e-3)" "unprognostic (2.13e-1)" "prognostic unfavorable (5.60e-5)" "unprognostic (6.82e-2)" "unprognostic (2.38e-3)" "unprognostic (4.93e-2)" "unprognostic (2.68e-1)" "unprognostic (3.07e-1)" "unprognostic (1.06e-3)" 4.8 0.4 0.5 0.5 0.6 0.2 1.9 0.3 0.9 67.8 0.2 7.8 4.0 0.4 0.6 334.0 7.9 10.0 0.4 0.6 0.2 5.8 0.7 6.3 0.1 0.5 0.3 0.6 3.2 0.0 0.6 2.4 0.4 230.6 4.8 0.0 23.5 1.9 0.3 11.1 2.5 0.1 0.2 0.4 3019.3 1.4 0.5 0.4 0.4 0.0 15.0 629.0 167.7 0.5 10.7 0.7 0.0 0.0 2.1 6.8 10.6 4.9 1.1 2.1 1.8 0.1 22.4 0.0 0.4 0.4 8.1 2.1 0.0 0.4 1.3 0.6 0.0 0.0 45.7 0.0 0.1 0.0 1.5 6.0 7.8 4.6 0.0 0.6 0.0 0.0 0.0 0.0 1.7 5.8 1.7 0.6 1.2 17.6 1.2 0.7 0.0 0.9 1.0 61.7 0.2 0.5 5.1 15.6 3.5 0.3 0.2 0.2 1.0 1.5 1.7 2.7 0.0 1.9 0.1 0.0 2.9 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.3 0.9 0.6 0.2 0.5 0.3 0.4 0.2 0.5 0.5 0.2 3.2 1.5 1.6 7.7 0.9 26.0 120.0 0.0 0.0 3.9 2.7 1.2 71.4 894.2 1.8 0.0 2.3 0.0 1.9 7.9 3.2 0.3 1.3 0.1 1.1 275.1 0.0 0.3 1.2 5.0 3.3 5332.3 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.2 12.9 179.0 0.6 1.0 0.4 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 57.1 0.2 0.0 13.4 238.7 0.3 0.4 994.9 0.0 0.0 0.0 48.9 0.0 0.5 13.1 1.3 28.5 4.6 0.0 0.9 1241.5 PSD2 "DKFZp761B0514, EFA6C" ENSG00000146005 "Pleckstrin and Sec7 domain containing 2" Q9BQI7 5 139795808-139844466 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 106.3" "Cell type enriched" "Detected in some" 4 "Astrocytes: 229.9" "Cancer enriched" "Detected in single" 43 "glioma: 19.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "THP-1: 1.1;U-2 OS: 1.1;U-698: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054625 Approved "Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "HPA054625: " "unprognostic (3.76e-2)" "unprognostic (1.90e-1)" "unprognostic (1.34e-3)" "unprognostic (2.48e-3)" "unprognostic (1.34e-2)" "unprognostic (5.01e-2)" "unprognostic (1.22e-2)" "unprognostic (6.55e-2)" "unprognostic (2.42e-1)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (4.02e-1)" "unprognostic (4.16e-3)" "unprognostic (3.40e-2)" "unprognostic (2.28e-1)" "unprognostic (3.07e-1)" "unprognostic (2.12e-3)" 0.1 0.3 70.8 0.3 91.3 0.2 0.5 86.5 63.1 0.8 22.0 0.2 0.1 0.2 1.6 0.0 0.4 0.2 0.2 58.7 76.3 0.1 0.1 0.1 0.0 90.6 106.2 0.1 0.4 0.0 0.9 0.0 79.2 0.2 0.1 4.1 1.7 0.4 0.3 0.1 0.1 0.1 70.5 0.2 0.1 1.1 106.3 1.0 0.1 0.0 0.1 0.1 0.2 56.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.5 0.9 0.0 0.2 0.0 0.0 0.0 1.1 0.0 0.3 1.1 0.0 0.0 0.2 0.0 1.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 70.8 91.3 86.5 63.1 58.7 76.3 90.6 106.2 79.2 70.5 106.3 56.3 0.0 0.0 0.0 229.9 0.0 0.0 0.1 0.0 0.0 1.9 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.2 0.2 0.0 0.0 9.1 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 10.3 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 6.5 0.0 2.6 0.0 52.8 24.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.6 0.0 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PTPRCAP "CD45-AP, LPAP" ENSG00000213402 "Protein tyrosine phosphatase receptor type C associated protein" Q14761 11 67435510-67437682 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "intestine: 79.7;lymphoid tissue: 174.1" "Group enriched" "Detected in some" 6 "B-cells: 203.3;Plasma cells: 283.5;T-cells: 233.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 351.1;HDLM-2: 242.3;HL-60: 140.6;MOLT-4: 206.8;NB-4: 996.9;U-698: 248.9" "Region enhanced" "Detected in single" "basal ganglia: 1.0" "Low region specificity" "Detected in many" HPA043734 Enhanced Approved "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane" "HPA043734: AB_10962214" 7.1 2.9 3.0 73.0 2.9 27.0 5.3 2.6 4.9 7.0 3.1 14.3 14.0 4.6 0.0 7.9 7.9 3.0 3.5 2.5 2.5 9.9 8.9 14.4 126.5 3.9 2.8 5.0 3.8 0.3 4.2 0.6 3.4 10.6 2.4 0.0 10.2 0.6 2.2 4.2 79.7 0.9 3.4 174.1 24.7 1.5 3.0 109.2 13.0 0.2 51.3 7.5 7.0 3.5 0.4 1.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.2 351.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 242.3 0.5 0.2 0.9 0.0 0.0 140.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 95.5 1.1 33.3 0.1 3.7 206.8 996.9 0.0 0.0 0.3 65.8 0.2 0.6 0.0 1.1 0.2 0.4 0.2 0.0 1.1 0.0 0.6 0.3 1.4 0.0 1.5 0.0 0.3 0.3 0.3 248.9 0.0 0.3 0.1 23.6 6.7 75.0 1559.9 5.6 1322.2 1334.4 955.3 1380.5 12.7 1714.2 688.5 1083.9 33.4 826.7 8.0 848.7 1374.2 1237.9 3.0 2.9 2.6 4.9 2.5 2.5 3.9 2.8 3.4 3.4 3.0 3.5 0.0 0.0 0.0 7.2 203.3 12.7 0.0 0.9 1.2 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.0 1.8 0.0 15.1 0.2 0.0 0.0 4.4 17.9 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.3 0.0 0.0 0.3 20.6 0.0 0.0 5.0 39.2 7.5 0.5 0.0 1.0 0.5 3.1 0.0 0.0 0.0 283.5 0.0 0.0 0.1 1.4 0.0 0.0 0.0 3.5 0.0 0.0 1.6 9.7 0.0 233.3 0.0 0.0 0.0 PTPRG "PTPG, RPTPG" ENSG00000144724 "Protein tyrosine phosphatase receptor type G" P23470 3 61561569-62297609 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 356.8;Excitatory neurons: 416.1;Inhibitory neurons: 684.3;Microglial cells: 771.0;Oligodendrocyte precursor cells: 920.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 81.7;HSkMC: 61.1" "Low region specificity" "Detected in all" "HPA000546, HPA064237" Uncertain Approved "Plasma membrane" NA NA 520000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "HPA000546: , HPA064237: AB_2685221" "unprognostic (1.47e-1)" "unprognostic (1.03e-1)" "unprognostic (1.31e-2)" "unprognostic (1.93e-1)" "unprognostic (8.73e-2)" "unprognostic (3.26e-1)" "unprognostic (5.38e-2)" "unprognostic (1.18e-2)" "unprognostic (5.84e-2)" "unprognostic (2.28e-1)" "unprognostic (2.86e-1)" "unprognostic (1.14e-1)" "prognostic favorable (3.10e-6)" "unprognostic (9.91e-2)" "unprognostic (3.25e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-2)" 18.0 13.2 7.6 4.6 7.8 0.0 12.8 4.9 10.4 11.9 23.4 8.2 3.7 10.6 8.4 4.1 9.0 8.3 10.0 13.7 6.2 14.4 5.8 12.8 1.8 8.4 7.2 12.0 3.9 26.6 5.2 9.9 5.9 7.8 6.1 8.6 5.2 8.4 7.4 4.5 5.9 13.0 10.0 7.0 5.8 7.7 9.1 2.1 13.1 10.4 1.7 7.0 6.7 5.0 0.0 5.3 27.3 0.0 81.7 41.6 13.5 17.6 28.5 18.2 24.4 13.2 0.5 0.6 10.1 20.7 14.5 0.2 13.4 13.6 28.3 1.5 7.7 1.4 0.1 15.0 27.5 7.5 0.1 61.1 5.3 25.9 30.9 5.8 19.7 2.0 0.0 17.3 16.3 7.6 0.0 0.1 17.0 0.1 0.0 11.9 8.6 0.6 18.2 8.2 2.1 4.5 4.3 0.1 6.9 11.2 0.2 0.3 46.0 25.4 24.1 41.0 14.7 5.5 6.8 0.0 19.2 3.2 31.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.6 7.8 4.9 10.4 13.7 6.2 8.4 7.2 5.9 10.0 9.1 5.0 45.3 12.8 32.4 356.8 2.2 9.2 6.4 5.0 13.1 98.5 9.6 6.3 12.5 8.6 5.8 22.0 6.2 10.5 0.9 12.1 5.9 9.6 3.6 14.4 31.9 55.5 24.6 0.0 416.1 1.8 0.8 47.7 4.1 30.5 0.0 64.6 90.3 32.7 19.7 154.8 684.3 8.9 22.4 2.9 8.8 4.3 66.5 1.1 17.8 771.0 0.6 40.8 2.1 920.3 11.8 5.3 5.6 56.8 4.2 10.9 13.9 18.2 2.8 5.7 72.3 81.1 60.6 2.0 8.6 2.1 4.8 12.6 2.3 20.0 12.1 2.7 PTPRM "hR-PTPu, PTPRL1, RPTPU" ENSG00000173482 "Protein tyrosine phosphatase receptor type M" P28827 18 7566782-8406861 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 142.0;Astrocytes: 188.1;Inhibitory neurons: 751.6;Microglial cells: 263.3;Oligodendrocyte precursor cells: 224.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory CD8 T-cell: 4.7" "Group enriched" "Detected in many" 33 "dendritic cells: 1.8;T-cells: 4.7" "Cell line enhanced" "Detected in many" "ASC diff: 98.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003891, CAB022442, CAB022443" Supported Approved "Plasma membrane" NA Yes 130000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB022442: , CAB022443: , HPA003891: AB_2667073" "unprognostic (2.59e-1)" "prognostic unfavorable (8.65e-5)" "unprognostic (4.89e-2)" "unprognostic (1.00e-1)" "unprognostic (1.13e-1)" "unprognostic (1.46e-1)" "unprognostic (1.80e-1)" "unprognostic (3.41e-2)" "unprognostic (7.62e-2)" "unprognostic (2.74e-2)" "unprognostic (1.56e-2)" "unprognostic (9.64e-2)" "unprognostic (5.63e-2)" "unprognostic (3.11e-3)" "unprognostic (9.41e-2)" "unprognostic (2.63e-2)" "prognostic favorable (1.07e-4)" 53.1 24.1 18.9 11.9 37.6 1.2 41.8 13.0 27.7 18.4 44.2 25.3 8.7 24.2 11.9 14.2 23.3 32.4 61.2 12.7 38.7 29.5 11.8 38.9 15.5 21.7 53.0 26.4 13.2 23.4 16.1 33.2 34.3 16.7 11.5 19.3 10.9 36.0 52.5 12.3 15.1 24.8 5.8 23.1 18.4 22.8 47.6 16.7 54.8 63.4 11.9 23.9 12.2 14.4 4.6 33.4 15.7 0.2 98.0 67.4 38.7 41.1 35.6 26.9 39.5 30.9 7.1 0.0 39.0 49.1 0.5 0.3 0.2 14.3 36.9 0.5 7.2 0.0 22.2 15.2 27.9 0.0 0.4 77.1 29.3 14.9 42.1 51.1 27.2 0.0 0.0 13.8 21.8 0.7 13.7 0.3 2.6 9.9 7.3 0.5 13.5 63.9 64.9 57.6 1.4 8.6 1.1 0.2 34.6 24.9 0.2 0.0 28.2 54.9 34.6 26.4 7.2 1.1 0.4 0.3 46.8 0.2 10.4 0.0 0.0 0.0 2.8 0.0 1.1 0.0 3.8 4.7 0.0 0.0 1.0 2.0 0.0 0.0 0.0 1.8 0.7 1.1 18.9 37.6 13.0 27.7 12.7 38.7 21.7 53.0 34.3 5.8 47.6 14.4 142.0 44.8 36.0 188.1 1.1 6.0 7.3 3.0 2.8 28.3 2.5 3.2 26.7 14.3 7.1 5.5 2.1 11.4 5.4 0.9 1.9 17.6 25.9 28.9 15.6 68.9 1.8 0.4 70.1 8.3 3.4 14.0 8.2 59.6 2.5 13.0 47.2 25.3 9.9 0.0 751.6 1.4 0.0 8.0 5.7 42.0 2.8 5.1 30.2 263.3 0.6 2.9 3.1 224.7 50.3 14.3 1.2 5.3 2.3 8.3 3.0 13.3 15.6 2.2 6.6 7.4 9.9 8.6 9.9 0.9 2.8 12.6 5.7 3.7 0.8 8.6 PTX3 "TNFAIP5, TSG-14" ENSG00000163661 "Pentraxin 3" P26022 3 157436850-157443633 "Plasma proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 231.5;urinary bladder: 191.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 16.2;Fibroblasts: 44.7;Glandular and luminal cells: 24.0;Langerhans cells: 23.6;Macrophages: 27.0;Melanocytes: 14.2" "Cancer enhanced" "Detected in many" "glioma: 22.5" "Group enriched" "Detected in some" 4 "cerebral cortex: 1.9;thalamus: 4.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1219.3;ASC TERT1: 1751.7;BJ hTERT+: 1201.8;HHSteC: 2261.1;HSkMC: 2364.2;hTEC/SVTERT24-B: 1276.5;TIME: 1761.1;U-2197: 1605.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA069320 Approved Approved "Plasma membrane" "Secreted to blood" NA NA 1090000 970000 "Cluster 52: Eosinophils - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA069320: AB_2686118" "unprognostic (1.93e-2)" "unprognostic (4.96e-3)" "unprognostic (1.35e-1)" "prognostic unfavorable (8.35e-9)" "unprognostic (5.79e-3)" "prognostic unfavorable (6.36e-4)" "unprognostic (6.03e-3)" "prognostic unfavorable (8.75e-6)" "unprognostic (2.45e-1)" "unprognostic (6.69e-2)" "unprognostic (7.60e-2)" "unprognostic (2.63e-1)" "unprognostic (2.76e-9)" "unprognostic (6.03e-3)" "unprognostic (5.98e-2)" "unprognostic (2.15e-4)" "unprognostic (1.92e-3)" 231.5 11.1 0.4 38.8 0.4 89.0 57.9 0.6 1.9 2.8 1.1 13.0 0.8 2.5 0.5 2.9 21.4 7.7 46.8 0.6 0.5 6.8 2.6 83.2 0.9 0.7 0.6 1.4 41.6 1.1 4.4 11.4 0.6 6.9 2.3 0.4 5.4 0.5 5.2 25.4 9.7 5.7 0.3 23.6 24.8 0.7 4.0 1.6 5.8 0.5 0.3 191.7 3.1 0.4 1.2 0.0 752.4 0.2 1219.3 1751.7 0.3 132.3 1201.8 56.2 60.9 0.7 7.9 0.2 460.6 157.4 87.6 0.0 0.3 1.1 110.5 0.8 0.3 2.0 0.1 0.0 2261.1 2.5 0.0 2364.2 0.8 1276.5 429.8 110.2 266.4 0.1 0.3 0.0 380.1 0.0 0.3 2.9 11.2 0.0 4.6 0.2 0.0 0.2 5.3 53.1 6.0 0.8 7.6 1.0 0.9 0.1 0.6 2.4 1761.1 252.2 12.2 1605.1 23.0 0.2 0.5 0.9 52.8 6.4 74.2 0.0 0.3 0.9 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.4 0.6 1.9 0.6 0.5 0.7 0.6 0.6 0.3 4.0 0.4 2.3 0.0 1.7 0.0 0.1 1.7 1.7 0.3 0.0 1.8 3.6 0.6 0.6 0.0 1.3 0.0 0.0 0.1 0.1 0.0 0.0 7.2 2.4 16.2 10.3 5.1 0.0 0.0 0.5 0.0 0.1 44.7 0.0 24.0 0.0 0.7 3.3 0.0 2.6 0.0 1.0 0.0 0.0 10.0 23.6 1.2 0.3 27.0 14.2 0.0 2.3 0.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 1.0 0.0 0.2 0.0 0.8 0.0 4.0 7.2 0.0 0.4 0.4 1.0 0.3 0.4 0.0 0.0 0.4 PXDC1 C6orf145 ENSG00000168994 "PX domain containing 1" Q5TGL8 6 3722614-3751713 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 168.7" "Cell type enhanced" "Detected in many" "Adipocytes: 103.6;Basal prostatic cells: 115.1;Extravillous trophoblasts: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 4 "memory B-cell: 1.2" "Lineage enriched" "Detected in single" 4 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "HHSteC: 151.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA019246 Approved "Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA019246: AB_2670113" "unprognostic (1.55e-1)" "unprognostic (1.87e-2)" "prognostic unfavorable (3.64e-4)" "prognostic unfavorable (1.14e-4)" "unprognostic (2.82e-2)" "unprognostic (3.80e-2)" "unprognostic (2.95e-1)" "unprognostic (1.48e-1)" "unprognostic (6.73e-2)" "unprognostic (6.08e-2)" "unprognostic (2.32e-1)" "unprognostic (2.13e-1)" "unprognostic (2.01e-2)" "unprognostic (6.17e-3)" "unprognostic (1.10e-1)" "unprognostic (2.97e-1)" "unprognostic (2.84e-1)" 68.0 14.9 33.7 14.7 34.6 1.4 50.5 35.1 36.5 30.3 49.3 37.2 29.9 31.4 15.6 25.5 28.3 48.3 36.0 33.0 35.2 25.9 168.7 47.6 13.0 39.5 36.1 19.2 26.7 14.2 13.9 61.8 36.4 29.8 7.7 3.1 39.3 19.8 16.9 38.7 26.5 26.7 36.9 19.0 28.5 5.6 35.7 7.4 44.6 15.6 6.7 46.3 28.7 36.0 44.5 17.5 28.6 19.9 87.9 66.4 99.4 75.6 57.7 62.6 48.2 30.6 8.8 0.0 49.0 123.9 48.0 34.4 5.7 20.8 29.3 43.2 6.6 0.0 14.7 26.8 151.4 0.1 0.2 59.0 67.2 38.8 83.2 52.7 70.2 3.0 0.1 5.9 49.7 2.7 0.1 0.5 1.3 9.0 27.3 2.5 16.0 2.1 24.4 35.7 3.1 1.6 51.7 52.4 115.5 38.3 4.6 2.7 77.8 56.9 24.7 22.2 54.4 0.1 0.1 0.2 13.6 0.1 40.5 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 33.7 34.6 35.1 36.5 33.0 35.2 39.5 36.1 36.4 36.9 35.7 36.0 103.6 48.1 8.6 8.1 8.1 48.3 115.1 11.8 40.9 0.6 28.0 27.7 8.1 18.6 11.7 7.3 0.0 32.8 1.5 0.6 11.7 33.2 0.5 4.7 18.3 39.6 0.0 5.3 0.1 51.6 131.0 62.1 14.8 5.6 3.8 1.6 45.7 68.7 25.1 0.0 2.6 1.4 8.2 9.7 80.8 0.9 22.7 31.6 24.9 9.4 22.0 16.0 0.0 11.1 2.5 77.6 0.1 18.0 4.4 55.8 25.7 20.4 9.6 0.8 0.0 38.7 33.4 0.6 4.5 17.5 33.1 78.4 3.2 0.4 1.2 47.4 RAB43 "ISY1, RAB11B, RAB41" ENSG00000172780 "RAB43, member RAS oncogene family" Q86YS6 3 129087569-129122801 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 46.9" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 12.0;Gastric mucus-secreting cells: 5.6;Plasma cells: 9.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 11.2" "Group enriched" "Detected in many" 5 "granulocytes: 11.2;T-cells: 2.8" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046840, HPA060085" Enhanced Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA046840: , HPA060085: AB_2684199" "unprognostic (3.01e-1)" "unprognostic (1.14e-2)" "unprognostic (3.08e-1)" "unprognostic (1.01e-1)" "unprognostic (5.08e-2)" "unprognostic (1.91e-1)" "unprognostic (9.36e-2)" "unprognostic (3.17e-2)" "unprognostic (4.16e-1)" "unprognostic (8.68e-2)" "unprognostic (3.14e-1)" "unprognostic (3.08e-1)" "unprognostic (2.46e-2)" "unprognostic (9.32e-2)" "unprognostic (5.82e-3)" "unprognostic (1.42e-1)" "unprognostic (2.71e-2)" 7.6 8.3 9.5 10.4 9.7 22.3 7.1 11.6 8.1 7.3 9.3 7.9 8.0 6.6 2.9 5.9 7.3 9.4 4.2 7.9 5.8 10.4 46.9 14.8 17.4 10.0 7.5 9.9 10.3 5.2 6.7 3.9 8.4 9.9 2.6 0.7 10.2 5.0 1.8 4.0 6.9 2.7 7.3 10.9 8.1 7.5 7.1 12.9 22.7 1.4 4.6 7.3 4.0 6.7 22.4 6.0 1.4 5.7 2.7 1.2 8.3 7.6 5.1 4.4 3.5 9.4 9.4 0.6 17.1 5.7 5.9 9.2 0.5 8.8 1.0 11.2 5.6 1.5 1.1 12.5 25.9 5.1 12.7 7.1 5.4 2.2 0.5 1.9 8.7 13.0 2.5 10.8 6.1 9.7 5.0 9.8 7.0 5.2 10.5 10.8 3.2 6.6 14.1 18.7 0.4 2.7 3.3 7.0 14.4 2.2 3.0 5.3 12.5 9.3 6.4 7.6 2.9 16.9 9.8 3.6 8.5 1.0 10.3 0.4 1.2 2.3 1.5 1.5 0.7 0.5 1.5 1.2 0.6 1.0 2.8 2.4 11.2 1.4 0.7 0.9 2.4 1.0 9.5 9.7 11.6 8.1 7.9 5.8 10.0 7.5 8.4 7.3 7.1 6.7 0.2 0.0 0.0 0.0 0.7 0.0 0.1 0.0 12.0 0.0 0.2 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.8 0.0 0.3 0.6 0.4 0.0 0.0 0.0 0.2 0.1 0.5 5.6 0.5 0.0 0.2 0.4 0.3 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.3 0.0 9.2 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.4 0.2 0.1 2.5 0.1 0.1 1.2 0.2 0.3 0.1 RABEPK "bA65N13.1, RAB9P40" ENSG00000136933 "Rab9 effector protein with kelch motifs" Q7Z6M1 9 125200542-125234161 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 85.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023920, HPA067106" Supported Uncertain "Plasma membrane" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 15: Liver - Metabolism" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "HPA023920: AB_1856023, HPA067106: " "unprognostic (8.72e-2)" "unprognostic (1.29e-1)" "unprognostic (1.76e-2)" "unprognostic (1.58e-1)" "unprognostic (3.24e-2)" "unprognostic (2.70e-2)" "unprognostic (3.47e-2)" "unprognostic (3.47e-2)" "unprognostic (9.74e-2)" "unprognostic (4.92e-2)" "unprognostic (1.27e-1)" "unprognostic (1.92e-1)" "unprognostic (1.52e-3)" "unprognostic (1.09e-1)" "unprognostic (1.63e-1)" "unprognostic (8.25e-2)" "unprognostic (2.69e-1)" 17.4 15.0 27.9 14.6 30.0 11.6 16.4 27.3 32.5 16.4 25.5 17.7 11.5 15.1 16.9 16.1 15.4 10.6 14.5 27.2 28.9 14.7 58.7 12.2 13.9 28.5 28.6 13.1 14.3 14.9 19.7 11.9 28.6 14.0 14.8 15.7 10.7 13.0 15.0 16.6 11.4 16.4 27.9 12.8 13.5 16.1 29.7 14.8 11.7 13.6 13.8 17.3 15.3 29.2 24.6 57.2 21.3 39.2 34.0 41.0 39.4 33.3 32.5 38.7 30.6 68.6 24.0 73.5 29.1 45.5 38.2 64.8 54.2 41.3 38.0 42.6 45.1 32.6 52.7 105.2 30.4 62.3 21.7 30.0 49.0 55.3 59.1 23.5 41.8 45.3 71.8 20.6 37.5 66.8 44.5 42.2 43.0 96.7 51.2 62.0 41.2 81.5 31.4 18.8 50.3 25.5 34.3 23.8 39.2 21.1 48.3 26.5 36.1 26.7 26.3 61.8 58.8 27.4 65.5 51.2 34.3 40.1 40.7 27.8 19.6 23.2 24.0 16.6 22.1 23.8 34.4 23.6 21.6 20.6 38.2 28.2 27.9 23.0 17.3 20.6 38.8 23.8 27.9 30.0 27.3 32.5 27.2 28.9 28.5 28.6 28.6 27.9 29.7 29.2 9.9 0.0 11.3 13.1 9.9 14.5 17.2 23.4 28.5 12.1 9.1 11.2 9.5 10.0 8.5 5.5 8.4 36.1 7.8 8.7 25.4 13.9 85.2 8.6 11.9 13.1 2.4 13.5 25.2 13.3 32.2 17.4 10.2 8.5 5.1 10.4 10.0 54.8 20.9 13.5 24.0 11.9 10.2 7.7 10.8 19.2 16.1 7.4 8.8 6.5 31.6 12.0 14.4 9.0 17.2 10.0 4.9 18.8 16.8 24.9 9.2 23.2 8.0 17.1 0.0 13.5 13.5 7.0 11.2 20.0 12.9 12.7 13.0 13.1 15.9 15.6 RAI2 ENSG00000131831 "Retinoic acid induced 2" Q9Y5P3 X 17800049-17861337 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 41.9;Leydig cells: 49.0;Peritubular cells: 70.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive CD8 T-cell: 1.8" "Lineage enriched" "Detected in single" 10 "T-cells: 1.8" "Cell line enriched" "Detected in some" 10 "ASC diff: 104.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051054 Uncertain Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA051054: AB_2681328" "unprognostic (3.45e-2)" "unprognostic (9.61e-2)" "unprognostic (2.41e-1)" "unprognostic (2.03e-2)" "unprognostic (1.98e-1)" "unprognostic (2.49e-2)" "unprognostic (4.10e-2)" "unprognostic (2.51e-2)" "unprognostic (1.44e-1)" "unprognostic (1.49e-1)" "prognostic favorable (2.77e-4)" "unprognostic (1.31e-2)" "prognostic favorable (3.39e-14)" "unprognostic (1.57e-2)" "unprognostic (2.33e-1)" "unprognostic (1.82e-2)" "unprognostic (2.80e-2)" 48.0 17.3 9.4 8.3 10.4 0.2 47.2 8.8 11.9 55.3 7.4 33.0 6.7 66.8 9.9 15.5 71.8 24.7 32.9 9.9 9.3 14.4 3.9 28.6 9.6 9.4 8.5 50.9 14.3 10.8 19.3 7.8 9.6 31.8 8.1 8.9 13.8 31.8 12.5 20.3 23.0 30.1 8.6 4.5 28.2 6.0 10.4 5.0 21.6 17.1 9.6 38.9 43.7 8.7 0.0 0.0 0.2 0.0 104.3 10.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 8.7 0.2 0.6 0.0 0.1 0.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.0 0.1 1.9 0.0 0.6 0.0 0.0 0.0 5.8 0.0 1.1 1.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 1.8 0.0 0.1 0.0 0.0 0.0 0.1 9.4 10.4 8.8 11.9 9.9 9.3 9.4 8.5 9.6 8.6 10.4 8.7 25.0 12.8 4.5 2.0 0.0 4.1 9.3 0.0 0.6 14.0 13.4 10.4 13.0 12.8 0.6 22.0 0.0 0.1 0.3 0.3 5.9 8.2 0.3 25.0 16.5 15.2 27.6 0.0 10.5 9.8 0.1 24.8 7.7 41.9 0.0 9.7 10.8 0.1 0.5 26.9 17.9 0.7 0.0 0.0 4.2 3.3 49.0 0.9 5.4 14.0 0.6 20.5 0.0 5.0 0.4 4.9 17.5 70.7 0.1 7.9 1.3 1.9 4.4 3.0 0.0 21.0 8.7 0.4 2.7 0.5 2.8 0.0 1.3 0.2 1.6 5.1 RAMP3 ENSG00000122679 "Receptor activity modifying protein 3" O60896 7 45157791-45186302 "FDA approved drug targets, Predicted membrane proteins, Transporters" Transport Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 144.6" "Group enriched" "Detected in many" 12 "Adipocytes: 287.8;Endothelial cells: 366.0;Hepatic stellate cells: 555.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 7 "Karpas-707: 2.5" "Group enriched" "Detected in all" 4 "cerebellum: 62.2;cerebral cortex: 49.2;thalamus: 174.9;white matter: 60.0" "Low region specificity" "Detected in all" HPA075527 Supported "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 2: Karpas-707 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA075527: " "unprognostic (1.62e-3)" "prognostic favorable (2.89e-4)" "unprognostic (4.85e-2)" "unprognostic (6.88e-3)" "unprognostic (3.68e-2)" "unprognostic (1.44e-3)" "prognostic favorable (2.50e-6)" "unprognostic (1.14e-1)" "unprognostic (2.35e-1)" "unprognostic (3.19e-1)" "unprognostic (2.79e-2)" "unprognostic (9.49e-2)" "unprognostic (1.09e-2)" "unprognostic (1.20e-2)" "unprognostic (2.43e-1)" "unprognostic (1.91e-1)" "unprognostic (9.21e-2)" 86.9 32.6 17.7 23.0 19.7 0.2 71.7 26.9 22.7 33.5 21.3 24.4 10.2 25.9 3.9 18.9 22.8 28.7 91.3 19.2 25.8 84.1 23.9 144.6 55.0 37.3 25.7 7.4 19.7 28.1 22.3 8.6 34.2 29.7 8.6 1.1 22.1 12.9 19.3 22.8 30.0 24.4 31.6 11.4 25.7 6.3 23.5 7.3 71.9 26.9 30.3 28.5 30.5 42.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.1 0.2 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 17.7 19.7 26.9 22.7 19.2 25.8 37.3 25.7 34.2 31.6 23.5 42.4 287.8 0.0 1.9 0.3 3.6 16.3 0.3 0.0 2.2 0.6 5.9 2.8 8.7 1.5 0.0 0.0 0.0 0.1 1.2 0.0 0.0 0.1 20.8 0.4 7.3 366.0 0.0 13.5 3.5 0.7 0.1 10.7 0.0 0.2 0.0 0.0 555.4 7.3 0.5 0.0 0.2 0.0 0.0 31.2 19.1 6.7 1.2 1.3 26.6 5.6 0.0 0.2 0.0 0.0 6.5 0.0 0.0 1.2 1.3 0.6 0.0 0.0 0.0 0.5 0.0 2.8 4.9 0.3 0.9 0.9 14.5 0.0 1.7 1.5 0.0 0.5 RASGRP2 CALDAG-GEFI ENSG00000068831 "RAS guanyl releasing protein 2" Q7LDG7 11 64726911-64745456 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 147.3;lymphoid tissue: 140.5" "Cell type enhanced" "Detected in many" "B-cells: 125.5;dendritic cells: 86.1;Kupffer cells: 77.3;Macrophages: 72.2;NK-cells: 98.9;Sertoli cells: 131.5" "Cancer enhanced" "Detected in many" "testis cancer: 5.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HEL: 103.4;HL-60: 192.8;NB-4: 347.1;REH: 105.0;THP-1: 108.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015635, HPA015667" Approved Supported "Plasma membrane" NA NA 1900000 "Cluster 37: B-cells - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 24: NB-4 - Immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA015635: , HPA015667: AB_1856090" "unprognostic (5.96e-2)" "unprognostic (3.24e-3)" "unprognostic (5.55e-2)" "unprognostic (1.50e-2)" "unprognostic (3.52e-2)" "unprognostic (4.74e-5)" "unprognostic (1.11e-2)" "unprognostic (7.36e-3)" "unprognostic (2.02e-1)" "unprognostic (3.33e-1)" "unprognostic (4.91e-3)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (1.08e-1)" "unprognostic (5.40e-2)" "unprognostic (1.90e-1)" "unprognostic (1.23e-1)" 23.8 10.1 16.1 52.9 35.5 147.3 16.8 9.6 22.4 20.1 7.1 37.5 6.6 28.3 4.6 9.1 29.2 8.7 51.7 13.4 13.4 15.8 10.1 29.5 106.0 12.4 16.3 9.1 4.1 1.0 5.5 10.9 11.9 23.2 5.3 1.3 4.6 18.6 12.2 6.1 86.4 15.0 9.5 140.5 17.5 11.9 20.7 34.6 10.6 10.2 62.0 26.7 15.5 9.8 0.1 0.1 3.0 0.1 0.0 0.3 8.7 1.3 0.2 1.2 0.8 1.5 0.2 62.8 2.7 0.2 0.8 0.7 5.4 0.9 0.3 0.3 1.7 103.4 0.0 0.4 0.3 192.8 35.9 0.0 0.0 0.5 0.0 0.0 0.1 25.9 4.1 1.1 0.0 1.4 45.4 347.1 2.5 0.4 0.0 105.0 0.2 4.4 0.0 0.0 0.5 2.3 0.1 0.1 0.0 2.2 0.6 108.5 0.6 0.0 2.0 1.5 0.1 0.5 0.1 58.9 0.0 58.2 0.0 64.4 34.1 59.9 70.4 88.0 37.3 170.7 72.9 57.2 34.5 100.2 92.7 83.1 70.9 55.3 105.8 85.9 93.8 67.5 16.1 35.5 9.6 22.4 13.4 13.4 12.4 16.3 11.9 9.5 20.7 9.8 27.4 3.2 1.8 2.6 125.5 2.3 0.1 0.0 0.0 2.6 1.6 3.7 53.1 2.8 0.0 0.0 0.0 1.7 86.1 0.1 0.0 0.0 6.6 1.9 27.1 13.5 0.0 24.2 6.0 0.0 1.3 6.6 2.6 1.2 3.8 5.7 31.4 1.7 6.1 0.0 12.2 0.1 0.0 77.3 19.7 19.5 18.0 72.2 0.0 6.5 55.8 0.7 98.9 2.5 0.9 0.0 0.0 47.8 28.6 0.1 0.4 0.9 0.7 2.5 131.5 5.4 56.8 18.0 43.9 0.9 1.3 11.8 61.0 0.8 0.3 0.2 RCSD1 "CapZIP, MGC21854, MK2S4" ENSG00000198771 "RCSD domain containing 1" Q6JBY9 1 167630093-167708696 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 115.5;skeletal muscle: 147.9" "Cell type enhanced" "Detected in many" "B-cells: 258.0;Kupffer cells: 137.5;Macrophages: 80.7;Microglial cells: 78.7;monocytes: 121.6;NK-cells: 142.2;Sertoli cells: 78.9;T-cells: 97.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 195.2;HDLM-2: 91.0;REH: 224.0;RPMI-8226: 139.7;THP-1: 103.4;U-266/70: 132.0;U-698: 132.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016597, HPA073490" Enhanced Approved "Plasma membrane" NA NA 200000 "Cluster 37: B-cells - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 14: REH - Unknown function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "HPA016597: AB_2669397, HPA073490: " "unprognostic (2.13e-2)" "unprognostic (7.38e-3)" "unprognostic (6.50e-3)" "unprognostic (1.37e-3)" "unprognostic (1.08e-1)" "prognostic favorable (2.97e-4)" "unprognostic (5.51e-2)" "unprognostic (8.90e-3)" "unprognostic (3.65e-1)" "unprognostic (8.48e-2)" "unprognostic (1.01e-1)" "unprognostic (6.33e-2)" "unprognostic (2.53e-3)" "unprognostic (3.19e-1)" "unprognostic (3.58e-2)" "unprognostic (6.94e-2)" "unprognostic (3.97e-2)" 14.2 5.8 5.5 42.9 6.1 55.7 11.6 5.8 6.3 5.6 5.9 12.0 8.8 4.6 2.5 8.6 4.0 11.7 25.6 5.2 6.3 5.2 8.0 16.8 88.7 9.9 7.3 2.8 1.5 2.4 2.0 17.5 8.4 3.7 11.9 0.6 4.7 3.9 147.9 2.8 29.3 8.6 6.8 52.4 12.4 3.7 7.7 115.5 6.1 50.6 73.7 14.0 3.4 10.0 0.3 0.0 0.2 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.1 0.0 195.2 0.6 0.2 0.0 0.2 0.0 0.0 0.0 91.0 0.3 1.6 0.1 0.1 0.2 34.4 3.7 0.5 0.3 0.4 0.0 0.0 0.0 76.0 67.8 56.7 25.4 0.0 69.3 49.8 1.7 0.0 0.0 224.0 0.8 139.7 0.0 0.1 0.1 0.1 0.2 0.6 0.1 2.7 0.1 103.4 0.5 0.2 0.6 0.2 0.4 132.0 42.5 132.0 0.1 64.6 0.0 249.3 170.3 271.3 63.5 119.8 76.9 216.4 81.7 80.0 103.4 201.7 68.1 64.7 165.7 130.0 122.7 54.3 129.4 148.9 5.5 6.1 5.8 6.3 5.2 6.3 9.9 7.3 8.4 6.8 7.7 10.0 18.7 3.2 6.7 0.3 258.0 1.1 1.2 0.0 3.4 0.7 6.2 10.7 46.8 0.0 3.1 1.8 0.0 0.5 73.9 0.1 0.0 0.2 0.8 0.4 2.1 18.8 0.0 30.1 4.2 0.0 0.5 12.4 4.1 0.3 13.9 0.2 19.2 1.5 44.2 0.0 0.7 0.0 0.0 137.5 26.9 1.7 0.9 80.7 5.4 78.7 121.6 0.2 142.2 2.0 0.6 0.1 0.0 0.4 55.1 0.8 0.0 0.5 0.0 0.8 78.9 5.8 39.7 0.0 0.3 1.0 1.7 1.2 97.2 0.6 0.1 0.3 RECK "hRECK, ST15" ENSG00000122707 "Reversion inducing cysteine rich protein with kazal motifs" O95980 9 36036913-36124455 "Plasma proteins, Predicted membrane proteins" "Wnt signaling pathway" "Protease inhibitor, Serine protease inhibitor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 63.1;Inhibitory neurons: 71.1;Oligodendrocyte precursor cells: 80.4;Oligodendrocytes: 119.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 199.5;ASC TERT1: 158.5;BJ: 65.1;BJ hTERT+: 93.0;fHDF/TERT166: 57.8;HSkMC: 71.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025109, HPA071729" Supported Supported "Plasma membrane" NA NA 64000000 "Cluster 27: Non-specific - Gene expression" "Cluster 46: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "CAB025109: , HPA071729: AB_2686438" "unprognostic (3.42e-1)" "unprognostic (4.01e-3)" "unprognostic (5.50e-2)" "unprognostic (5.05e-4)" "unprognostic (8.87e-2)" "unprognostic (8.47e-2)" "unprognostic (2.24e-1)" "unprognostic (2.23e-1)" "unprognostic (3.75e-2)" "unprognostic (1.51e-2)" "unprognostic (9.06e-2)" "unprognostic (8.48e-2)" "unprognostic (7.45e-2)" "prognostic unfavorable (7.31e-4)" "unprognostic (2.68e-2)" "unprognostic (1.50e-2)" "unprognostic (3.60e-2)" 14.7 7.4 3.0 4.6 3.3 1.2 13.7 3.4 4.3 15.2 2.7 6.8 3.7 14.4 6.1 11.7 8.0 13.7 8.5 4.6 3.3 5.7 5.8 12.7 5.8 3.4 3.1 14.3 3.2 3.7 3.1 11.3 3.5 8.3 6.3 4.7 4.7 7.3 3.7 7.6 5.1 14.7 3.1 7.3 5.7 3.2 3.4 6.6 6.2 16.0 4.4 12.1 7.5 4.0 1.4 2.4 8.0 4.4 199.5 158.5 0.1 65.1 93.0 4.7 11.0 0.0 0.0 2.5 6.0 57.8 3.7 0.4 1.8 1.2 6.4 4.1 3.7 2.6 2.8 0.2 16.2 0.3 11.1 71.3 1.6 7.1 2.7 18.4 14.6 4.8 0.0 2.1 12.2 0.3 6.6 1.0 2.7 0.0 2.0 6.9 6.2 0.0 3.2 0.2 0.7 4.5 1.5 0.8 2.7 8.3 0.0 8.9 44.4 9.0 3.3 5.9 3.6 2.9 3.4 2.7 5.5 8.7 5.8 1.0 2.6 0.7 3.9 2.8 4.4 1.2 5.2 4.2 2.9 2.7 6.3 4.6 0.3 3.0 4.8 1.6 2.6 2.3 3.0 3.3 3.4 4.3 4.6 3.3 3.4 3.1 3.5 3.1 3.4 4.0 12.8 3.2 5.4 40.1 11.7 7.1 4.0 5.0 4.6 12.5 4.2 5.6 3.6 1.5 2.5 3.7 14.6 0.9 9.3 0.2 0.0 6.6 38.3 0.9 11.6 19.6 6.1 5.7 63.1 1.5 7.7 53.4 3.6 0.6 9.5 9.2 25.4 1.1 15.6 8.4 71.1 1.3 4.1 15.7 15.9 35.5 18.6 8.3 3.6 41.2 8.8 14.3 2.1 80.4 119.8 1.3 0.4 17.7 5.9 4.3 0.3 1.6 4.1 7.8 0.0 14.2 15.3 41.2 27.4 1.3 7.5 0.8 10.2 7.8 0.8 1.2 RFTN2 "C2orf11, FLJ30574, Raftlin-2" ENSG00000162944 "Raftlin family member 2" Q52LD8 2 197568224-197676045 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 70.9" "Group enriched" "Detected in many" 7 "Astrocytes: 152.8;Early spermatids: 125.0;Late spermatids: 351.7;Oligodendrocyte precursor cells: 198.5;Oligodendrocytes: 320.6" "Cancer enriched" "Detected in many" 5 "glioma: 10.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 19.8;ASC diff: 15.5;ASC TERT1: 8.7;HSkMC: 10.7;TIME: 6.4;WM-115: 9.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035232, HPA043190" Approved Approved "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA035232: AB_10601495, HPA043190: " "unprognostic (1.15e-1)" "unprognostic (3.52e-1)" "unprognostic (2.07e-2)" "unprognostic (1.00e-1)" "prognostic favorable (8.05e-4)" "unprognostic (1.89e-2)" "unprognostic (1.81e-1)" "unprognostic (3.09e-2)" "unprognostic (2.16e-2)" "unprognostic (6.04e-2)" "unprognostic (1.39e-1)" "unprognostic (1.05e-1)" "unprognostic (8.44e-3)" "unprognostic (2.56e-2)" "unprognostic (1.01e-1)" "unprognostic (1.62e-1)" "unprognostic (6.77e-2)" 10.8 4.7 30.0 1.9 48.9 0.3 3.2 39.2 32.6 4.4 3.7 1.8 0.7 4.6 1.2 2.5 2.2 4.4 3.4 28.3 29.4 2.0 1.0 2.4 2.5 42.5 36.6 9.9 1.9 0.6 0.7 6.2 49.5 1.7 1.9 4.3 3.3 1.6 1.5 2.3 1.3 3.3 40.2 1.9 1.5 3.0 33.7 0.8 1.9 5.8 1.5 2.7 2.4 70.9 0.2 0.0 19.8 0.4 15.5 8.7 0.7 0.2 1.3 0.0 1.1 0.3 0.4 0.4 0.5 1.8 0.4 0.6 0.0 0.0 0.0 0.8 0.1 0.1 1.0 0.0 2.2 0.3 0.3 10.7 0.4 0.1 0.0 0.1 2.3 0.6 0.0 0.2 0.4 0.9 0.1 0.1 0.8 0.8 0.6 0.1 0.5 0.2 0.0 0.2 0.5 0.2 0.0 0.0 3.0 3.4 0.1 0.0 6.4 1.7 0.3 0.1 0.3 0.5 1.1 0.2 1.6 0.0 9.6 0.2 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.1 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.1 0.1 0.0 30.0 48.9 39.2 32.6 28.3 29.4 42.5 36.6 49.5 40.2 33.7 70.9 14.8 0.0 0.6 152.8 0.2 2.4 0.2 0.1 0.0 1.3 1.3 1.4 2.2 2.8 0.1 0.0 0.0 0.2 0.5 0.1 0.0 1.0 125.0 0.9 9.7 13.0 0.0 0.0 1.2 0.0 0.1 16.3 0.0 0.4 0.0 8.6 19.6 0.3 0.4 3.3 1.5 0.0 0.0 0.6 3.3 351.7 15.8 0.7 16.0 32.8 0.0 23.5 0.0 198.5 320.6 0.1 0.0 22.2 1.6 0.3 0.0 0.1 0.2 1.5 6.6 16.2 8.3 4.5 2.8 0.5 2.3 0.0 0.6 3.3 0.0 0.1 RGS3 "C2PA, FLJ20370, PDZ-RGS3" ENSG00000138835 "Regulator of G protein signaling 3" P49796 9 113444731-113597743 "Plasma proteins, Predicted intracellular proteins" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endothelial cells: 111.6;Horizontal cells: 158.2;Proximal tubular cells: 195.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "BJ hTERT+: 248.4;HDLM-2: 413.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044234 Supported "Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA044234: " "prognostic unfavorable (9.93e-4)" "unprognostic (4.04e-2)" "unprognostic (5.33e-3)" "unprognostic (6.71e-3)" "unprognostic (1.49e-2)" "unprognostic (1.69e-2)" "prognostic unfavorable (6.62e-4)" "unprognostic (6.79e-2)" "unprognostic (9.17e-2)" "unprognostic (2.24e-1)" "unprognostic (8.59e-3)" "unprognostic (3.04e-1)" "unprognostic (2.51e-3)" "unprognostic (1.52e-2)" "unprognostic (1.45e-1)" "unprognostic (8.53e-2)" "unprognostic (2.90e-1)" 60.5 31.5 32.0 18.1 37.3 9.3 43.7 33.7 29.7 17.9 49.7 30.4 16.9 20.8 11.4 10.8 15.2 42.4 95.0 24.0 31.5 70.9 54.5 64.2 23.9 32.2 44.3 10.3 23.9 12.3 16.6 32.3 32.5 26.3 15.8 10.3 10.8 10.2 48.2 15.2 20.0 18.0 28.2 31.9 27.6 31.2 58.0 7.9 24.5 19.2 11.4 26.5 15.4 34.0 4.5 16.6 40.1 37.0 12.2 18.1 2.9 41.2 248.4 32.9 27.9 40.8 14.7 17.9 29.7 33.6 32.8 10.6 0.6 16.0 19.2 413.2 0.1 1.7 13.0 24.8 24.8 0.4 5.5 32.4 16.6 91.4 13.2 72.6 125.4 1.0 0.3 17.1 60.5 18.7 1.2 1.9 10.6 28.6 13.7 1.3 19.8 2.9 67.7 8.1 31.3 4.2 3.9 31.3 24.7 19.6 21.5 3.8 61.2 109.7 11.8 5.1 79.1 8.6 1.5 2.7 126.2 3.8 51.6 10.2 6.8 3.7 24.7 7.1 16.7 2.4 5.7 20.3 6.6 2.4 2.4 10.8 18.5 42.3 6.0 0.3 3.8 15.6 32.0 37.3 33.7 29.7 24.0 31.5 32.2 44.3 32.5 28.2 58.0 34.0 49.5 16.0 13.9 14.4 5.6 12.0 9.9 7.4 4.6 1.4 9.1 10.7 55.8 72.9 8.4 22.0 6.2 4.6 23.5 28.0 82.2 65.1 38.8 9.9 14.9 111.6 0.0 6.1 2.4 30.4 3.7 29.3 27.0 4.0 47.7 12.8 66.0 35.2 15.6 158.2 3.4 7.4 4.1 14.3 13.8 17.4 4.7 14.6 55.2 21.5 10.3 3.5 50.4 3.5 24.4 31.0 23.4 13.9 4.5 5.0 20.5 195.7 7.5 6.4 6.6 8.4 35.4 9.9 1.8 4.1 11.4 3.0 18.4 55.5 11.5 12.9 RGS9BP "FLJ45744, PERRS, R9AP" ENSG00000186326 "Regulator of G protein signaling 9 binding protein" Q6ZS82 19 32675848-32678300 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "choroid plexus: 28.9;retina: 17.4;skeletal muscle: 9.0" "Group enriched" "Detected in some" 5 "Bipolar cells: 29.0;Cone photoreceptor cells: 56.3;Rod photoreceptor cells: 75.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 6.3;HMC-1: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" HPA049791 Enhanced Approved "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 36: HEL - Hemostasis" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA049791: AB_2680884" "unprognostic (2.82e-2)" "unprognostic (6.99e-3)" "unprognostic (2.44e-3)" "unprognostic (1.20e-7)" "unprognostic (1.49e-1)" "unprognostic (1.21e-2)" "unprognostic (1.17e-2)" "unprognostic (1.32e-1)" "unprognostic (2.80e-1)" "unprognostic (6.71e-2)" "unprognostic (6.74e-2)" "unprognostic (3.89e-2)" "unprognostic (1.63e-3)" "unprognostic (2.29e-1)" "unprognostic (8.22e-2)" "unprognostic (5.23e-2)" "unprognostic (5.34e-2)" 0.0 0.1 0.8 0.0 0.7 0.0 0.0 0.8 0.8 0.0 28.9 0.1 0.0 0.0 0.1 0.4 0.0 0.0 1.3 3.3 0.9 0.3 0.0 0.3 0.0 1.1 1.4 0.0 0.0 0.2 0.2 0.0 0.9 0.2 0.0 17.4 0.1 0.1 9.0 0.1 0.0 0.0 0.5 0.0 0.1 0.4 1.5 0.1 0.0 3.2 0.0 0.4 0.0 0.7 0.1 0.1 0.0 0.5 0.3 0.1 0.3 0.0 0.3 0.2 0.1 0.0 0.1 0.1 0.3 0.0 0.3 0.0 1.0 0.0 0.0 0.2 0.1 6.3 0.1 0.0 0.1 0.1 1.6 0.0 0.3 0.0 0.2 0.1 0.0 0.0 0.4 0.8 0.1 0.2 0.0 1.0 0.0 0.0 1.1 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.6 0.3 0.0 0.2 0.3 0.1 0.1 0.3 0.4 0.0 0.1 0.3 0.4 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.7 0.8 0.8 3.3 0.9 1.1 1.4 0.9 0.5 1.5 0.7 0.2 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 29.0 0.4 0.4 4.6 0.0 0.0 1.8 56.3 0.3 0.6 0.5 0.0 0.0 5.1 0.2 0.1 0.7 0.0 0.8 0.0 0.0 0.2 0.2 0.0 0.4 0.0 1.8 0.7 0.0 0.2 1.7 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.1 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.4 0.9 0.0 75.4 0.0 0.4 0.2 0.5 0.4 0.0 0.0 0.0 0.1 1.1 0.4 0.0 RHEX "C1orf186, FLJ16052" ENSG00000263961 "Regulator of hemoglobinization and erythroid cell expansion" Q6ZWK4 1 206053173-206102449 "Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 24.4" "Group enriched" "Detected in some" 14 "Endometrial ciliated cells: 202.9;Glandular and luminal cells: 337.5;granulocytes: 334.3" "Group enriched" "Detected in many" 5 "endometrial cancer: 42.8;ovarian cancer: 41.1;renal cancer: 27.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 152 "basophil: 1312.1" "Lineage enriched" "Detected in single" 1544 "granulocytes: 1312.1" "Cell line enriched" "Detected in some" 5 "HMC-1: 1562.9" "Low region specificity" "Detected in all" HPA037859 Supported "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA037859: AB_10697084" "unprognostic (9.26e-3)" "unprognostic (1.91e-2)" "unprognostic (9.66e-2)" "unprognostic (1.65e-2)" "unprognostic (2.06e-2)" "unprognostic (5.27e-3)" "unprognostic (9.55e-2)" "unprognostic (3.04e-3)" "unprognostic (2.36e-1)" "unprognostic (1.31e-2)" "unprognostic (1.35e-1)" "unprognostic (7.20e-3)" "unprognostic (1.89e-2)" "unprognostic (3.02e-2)" "unprognostic (1.35e-1)" "unprognostic (3.77e-2)" "unprognostic (2.80e-3)" 4.1 0.4 0.0 2.9 0.0 1.3 4.7 0.0 0.0 24.4 0.0 7.5 3.3 12.8 16.3 7.7 5.3 16.3 0.9 0.0 0.0 14.3 0.9 10.7 4.1 0.0 0.0 0.2 1.4 0.3 0.4 0.6 0.0 2.8 7.4 0.0 2.8 20.0 1.0 4.5 6.7 7.3 0.0 3.0 6.4 1.0 0.1 3.1 2.0 2.5 4.6 7.7 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 13.9 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 143.8 0.0 0.9 0.0 75.2 1562.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.5 0.0 0.0 5.9 330.8 0.0 0.0 0.0 0.1 0.2 0.7 20.0 2.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 8.5 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.6 0.9 1.1 0.8 1312.1 0.0 8.6 0.0 0.1 0.1 0.5 0.2 0.0 0.6 0.2 0.1 0.2 0.5 0.0 0.2 0.8 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 13.6 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 20.2 0.0 2.3 0.7 0.0 1.9 3.6 0.0 202.9 17.6 1.3 0.0 0.0 0.0 0.2 0.2 0.4 0.0 337.5 334.3 1.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 5.0 0.0 0.0 13.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 3.0 0.0 0.0 0.0 RHOBTB2 "DBC2, KIAA0717" ENSG00000008853 "Rho related BTB domain containing 2" Q9BYZ6 8 22987417-23020199 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lung: 50.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 64.1;Alveolar cells type 2: 77.7;Excitatory neurons: 33.3;Proximal enterocytes: 57.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 85.7;hTCEpi: 73.6;RT4: 126.9" "Low region specificity" "Detected in all" HPA060938 Approved Approved "Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA060938: AB_2684391" "unprognostic (2.67e-3)" "unprognostic (1.64e-1)" "unprognostic (1.64e-1)" "unprognostic (7.94e-2)" "unprognostic (7.83e-3)" "unprognostic (2.13e-2)" "unprognostic (8.13e-2)" "unprognostic (8.17e-2)" "unprognostic (3.47e-3)" "unprognostic (1.93e-2)" "unprognostic (1.60e-2)" "unprognostic (1.46e-2)" "prognostic favorable (2.98e-4)" "unprognostic (2.01e-1)" "unprognostic (1.09e-1)" "unprognostic (8.89e-3)" "unprognostic (2.43e-1)" 6.5 8.8 17.9 7.5 31.7 2.3 8.4 3.6 27.6 6.8 7.1 6.2 8.5 7.7 5.3 4.8 9.8 6.5 21.8 21.4 7.3 11.2 2.4 50.5 14.9 4.2 10.3 25.8 8.0 9.6 14.2 11.2 4.1 7.7 2.5 5.6 6.4 23.0 16.5 5.5 21.2 6.5 0.8 12.6 8.3 8.1 22.8 8.9 18.5 13.6 16.7 10.4 4.5 15.1 6.8 13.2 10.4 16.7 12.4 8.7 14.0 9.2 12.0 14.2 10.7 34.2 6.6 85.7 13.8 13.3 18.5 13.2 5.0 51.5 6.8 7.4 3.0 9.3 17.8 9.7 6.0 5.5 18.5 11.3 73.6 14.8 7.4 9.8 10.4 6.1 2.3 8.2 9.5 19.7 3.5 8.8 11.0 19.7 9.2 4.7 16.8 5.9 10.1 126.9 6.8 12.5 7.1 21.2 14.5 7.7 4.0 14.0 12.8 17.7 12.8 32.0 10.6 20.7 21.5 30.2 17.2 7.9 14.0 2.9 0.6 0.8 1.7 1.0 1.1 5.1 0.4 0.8 0.6 4.3 0.6 0.6 0.1 2.9 1.1 1.8 0.9 0.8 17.9 31.7 3.6 27.6 21.4 7.3 4.2 10.3 4.1 0.8 22.8 15.1 4.1 64.1 77.7 13.1 7.6 2.9 2.5 5.2 2.8 31.1 2.9 3.2 10.2 5.7 9.1 7.3 4.2 14.7 4.5 0.2 1.9 2.1 0.8 1.9 4.8 6.2 6.0 1.3 33.3 3.7 8.5 5.5 6.1 3.2 4.5 2.4 7.9 1.9 14.3 16.8 13.1 5.8 0.0 2.5 2.6 0.8 6.2 3.5 1.8 5.6 1.5 7.3 8.2 7.1 1.8 4.1 2.6 6.4 4.2 1.2 57.2 6.2 3.1 6.1 0.0 7.2 4.2 0.9 1.9 0.5 0.6 5.6 2.5 2.9 2.8 0.9 ROBO1 "DUTT1, FLJ21882, SAX3" ENSG00000169855 "Roundabout guidance receptor 1" Q9Y6N7 3 78597239-79767998 "Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 309.4;Inhibitory neurons: 1518.9;Oligodendrocyte precursor cells: 348.3;Oligodendrocytes: 479.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013524, HPA052968, HPA074461" Uncertain Enhanced "Plasma membrane" NA NA 16000000 "Cluster 32: T-cells - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB013524: , HPA052968: AB_2682001, HPA074461: AB_2732256" "unprognostic (2.89e-1)" "unprognostic (6.42e-2)" "unprognostic (2.29e-2)" "unprognostic (1.30e-1)" "unprognostic (4.77e-2)" "unprognostic (1.61e-3)" "prognostic unfavorable (9.88e-4)" "unprognostic (2.44e-1)" "unprognostic (2.92e-2)" "unprognostic (2.00e-1)" "unprognostic (6.40e-2)" "unprognostic (1.42e-1)" "unprognostic (1.65e-1)" "unprognostic (6.77e-2)" "unprognostic (1.91e-1)" "unprognostic (2.39e-2)" "unprognostic (1.16e-2)" 12.4 8.6 12.7 10.7 13.7 0.2 4.9 4.3 9.5 13.4 0.0 7.8 3.1 9.5 7.2 12.3 4.7 7.7 6.7 7.8 10.8 3.1 3.6 7.6 9.3 8.8 16.3 16.4 1.9 1.8 7.4 7.8 9.9 12.9 6.0 3.9 5.4 11.9 4.5 20.5 4.3 10.5 7.5 9.0 4.8 10.3 15.5 13.3 4.8 5.4 18.2 13.9 11.1 12.4 0.2 26.9 25.7 41.3 35.0 22.8 1.4 21.1 28.0 16.3 13.8 0.6 11.5 0.0 0.1 26.2 13.0 10.9 31.5 21.6 20.5 0.4 39.1 16.4 51.4 43.4 8.4 0.3 4.1 38.3 28.9 61.9 29.1 30.5 16.5 0.0 2.2 49.0 16.8 13.1 0.0 0.1 32.8 7.9 9.6 0.9 27.2 0.3 0.1 8.9 19.7 13.7 45.5 9.9 16.2 24.6 31.8 0.4 0.3 54.1 23.4 32.7 36.1 1.7 0.0 0.0 49.2 0.1 45.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 12.7 13.7 4.3 9.5 7.8 10.8 8.8 16.3 9.9 7.5 15.5 12.4 4.3 3.2 11.0 81.0 1.9 33.1 20.6 17.9 39.9 11.7 4.1 3.6 3.6 0.0 9.0 7.3 4.2 9.7 0.0 0.1 0.0 0.5 23.9 1.6 23.2 14.3 1.2 4.0 309.4 0.2 8.3 34.6 3.6 2.3 1.3 5.1 16.1 0.3 1.5 1.7 1518.9 1.4 22.4 2.6 10.0 65.9 19.9 1.5 14.2 51.5 1.9 5.7 0.0 348.3 479.3 0.2 5.1 24.5 1.3 20.5 4.9 0.4 2.9 1.0 13.1 24.7 16.8 2.7 7.0 30.3 33.8 5.6 0.9 71.1 2.6 52.7 ROBO4 "ECSM4, FLJ20798, MRB" ENSG00000154133 "Roundabout guidance receptor 4" Q8WZ75 11 124883691-124898500 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 7 "Adipocytes: 181.5;Endothelial cells: 119.7;Hepatic stellate cells: 148.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "HUVEC TERT2: 247.6;TIME: 224.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065212 Approved "Plasma membrane" NA NA 380000000 "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA065212: AB_2685434" "unprognostic (2.86e-1)" "unprognostic (9.35e-2)" "unprognostic (2.67e-1)" "unprognostic (1.07e-1)" "unprognostic (3.82e-2)" "unprognostic (6.97e-2)" "prognostic favorable (4.85e-4)" "unprognostic (7.94e-2)" "unprognostic (2.27e-1)" "unprognostic (1.43e-1)" "unprognostic (1.73e-3)" "unprognostic (2.17e-1)" "unprognostic (1.17e-2)" "prognostic unfavorable (8.73e-4)" "unprognostic (1.55e-1)" "unprognostic (4.63e-1)" "unprognostic (5.15e-2)" 41.4 7.2 11.4 6.6 9.6 0.2 31.8 9.0 9.4 10.0 5.8 6.5 2.9 10.9 2.1 5.5 10.3 9.7 25.8 7.9 9.2 18.5 5.3 34.8 7.8 11.3 10.7 4.1 4.3 4.7 4.6 28.6 11.2 7.0 1.7 0.2 4.1 4.6 13.9 6.9 7.3 9.9 9.5 43.5 6.3 1.4 13.2 1.8 16.7 11.9 2.0 9.4 7.0 8.6 0.4 0.0 0.4 0.0 0.0 1.1 0.1 0.2 3.1 0.7 1.5 0.0 0.0 0.0 23.6 0.1 1.0 0.0 0.0 0.4 1.2 0.0 0.0 0.9 0.0 0.1 0.6 0.0 0.0 0.1 0.0 8.9 3.0 0.4 247.6 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.0 0.0 3.4 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 224.8 1.2 0.6 0.3 1.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.4 9.6 9.0 9.4 7.9 9.2 11.3 10.7 11.2 9.5 13.2 8.6 181.5 0.0 4.2 2.3 1.6 2.2 1.0 0.2 0.6 0.2 0.6 1.0 3.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.5 0.5 0.2 0.3 119.7 0.0 4.0 0.0 0.2 0.0 5.2 0.0 0.3 2.5 0.6 148.9 1.5 0.1 0.0 0.0 0.0 0.0 8.1 3.7 1.7 4.4 2.8 1.8 20.6 0.1 1.1 0.0 0.5 0.1 0.1 0.0 1.2 2.6 0.3 0.0 0.0 0.0 5.2 0.0 4.5 2.1 0.0 0.1 0.6 1.3 0.0 0.9 2.0 0.1 0.2 SCN7A "NaG, Nav2.1, Nav2.2, SCN6A" ENSG00000136546 "Sodium voltage-gated channel alpha subunit 7" Q01118 2 166403573-166611482 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 45.4" "Group enriched" "Detected in many" 4 "Fibroblasts: 102.0;Leydig cells: 100.9;Peritubular cells: 159.9;Sertoli cells: 151.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.1" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.1" "Group enriched" "Detected in some" 5 "HDLM-2: 7.9;HMC-1: 4.5;Karpas-707: 5.8;SK-BR-3: 15.4" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 7.6" HPA072715 Approved Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "HPA072715: " "unprognostic (1.22e-1)" "unprognostic (6.42e-3)" "unprognostic (9.72e-2)" "unprognostic (7.43e-2)" "unprognostic (2.18e-1)" "unprognostic (1.78e-1)" "unprognostic (1.86e-1)" "unprognostic (4.00e-3)" "unprognostic (5.21e-2)" "unprognostic (6.84e-3)" "unprognostic (6.88e-2)" "unprognostic (1.27e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-2)" "unprognostic (1.47e-2)" "unprognostic (1.35e-1)" "unprognostic (1.22e-4)" 4.6 8.6 3.4 3.4 3.0 0.3 10.2 0.1 1.8 7.8 0.0 35.8 3.4 9.0 6.3 10.1 10.9 3.8 20.6 1.1 7.1 1.8 1.2 27.6 0.5 4.0 7.1 45.4 4.9 0.7 1.0 12.3 5.4 11.0 8.5 10.6 6.1 10.1 7.2 2.4 6.8 7.6 2.9 3.2 7.8 5.6 9.8 3.2 1.2 15.0 0.4 4.7 7.1 1.2 0.1 0.1 0.7 0.9 0.2 0.0 0.8 0.7 0.0 1.3 0.0 0.6 0.2 0.4 0.1 0.0 0.3 0.3 0.1 0.1 0.0 7.9 0.5 0.2 1.5 0.6 0.0 0.2 4.5 0.0 0.0 0.4 0.1 0.4 0.0 0.4 1.2 5.8 0.0 1.0 0.8 0.5 1.1 0.3 0.3 0.0 0.5 0.0 0.1 0.8 0.2 0.4 0.3 15.4 0.0 0.3 0.4 0.1 0.4 0.2 1.0 0.7 0.4 1.0 0.3 1.1 0.2 0.2 0.4 1.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.8 3.4 3.0 0.1 1.8 1.1 7.1 4.0 7.1 5.4 2.9 9.8 1.2 1.4 0.0 1.1 1.0 0.0 0.3 0.2 0.0 5.7 21.5 0.2 0.3 16.2 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.9 0.0 2.4 0.0 0.3 4.1 0.0 0.0 7.7 0.0 0.0 102.0 0.0 0.0 15.9 0.1 9.3 0.0 0.2 0.0 20.9 0.0 0.0 0.0 1.2 4.1 100.9 1.8 5.4 14.0 0.0 4.9 0.0 14.1 0.3 0.1 0.0 159.9 1.2 0.5 0.0 0.5 0.0 1.8 151.2 16.7 26.1 0.5 1.2 1.7 1.1 0.0 0.2 0.3 0.0 0.3 SCUBE3 "CEGF3, FLJ34743" ENSG00000146197 "Signal peptide, CUB domain and EGF like domain containing 3" Q8IX30 6 35213956-35253079 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "thyroid gland: 28.9" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 10.8;Horizontal cells: 10.1;Rod photoreceptor cells: 7.1" "Cancer enhanced" "Detected in many" "thyroid cancer: 9.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 26.0;ASC diff: 76.7;ASC TERT1: 102.2;HSkMC: 48.1;hTEC/SVTERT24-B: 30.1;U-138 MG: 29.1;WM-115: 25.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA040606 Uncertain Approved "Plasma membrane" "Secreted to blood" NA NA 1890000 490000 "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA040606: AB_10795383" "unprognostic (1.45e-1)" "unprognostic (1.79e-2)" "unprognostic (2.22e-1)" "unprognostic (2.41e-3)" "unprognostic (1.52e-1)" "unprognostic (1.27e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (2.00e-2)" "unprognostic (7.41e-2)" "unprognostic (1.57e-1)" "unprognostic (2.64e-2)" "unprognostic (4.83e-8)" "unprognostic (1.54e-2)" "unprognostic (2.12e-1)" "prognostic unfavorable (1.38e-4)" "unprognostic (3.06e-3)" 1.7 2.4 0.7 0.9 1.1 0.1 0.4 2.0 1.0 0.5 2.9 4.2 0.1 0.6 0.9 0.7 0.8 0.5 3.4 0.5 0.6 2.9 0.1 0.7 0.1 0.8 1.0 0.5 0.1 0.1 1.7 0.7 0.3 2.2 0.9 1.4 0.2 4.5 0.3 0.8 0.7 0.9 0.1 0.2 1.4 1.1 0.7 0.1 28.9 0.0 0.2 5.1 0.9 0.8 0.0 0.1 26.0 0.2 76.7 102.2 0.3 6.7 3.3 0.1 0.1 0.5 0.1 0.0 0.9 15.5 0.0 0.0 5.3 0.0 0.4 0.0 0.1 0.0 0.7 0.1 0.1 0.0 0.0 48.1 0.0 30.1 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.3 0.0 0.0 1.2 0.0 0.4 0.1 0.0 0.0 0.1 2.9 0.5 0.0 0.1 0.7 1.9 10.2 0.7 0.1 1.5 29.1 1.3 0.0 0.2 0.1 0.0 0.0 4.6 0.0 25.2 0.3 0.1 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.4 0.1 0.1 0.2 0.1 0.0 0.7 1.1 2.0 1.0 0.5 0.6 0.8 1.0 0.3 0.1 0.7 0.8 0.2 0.0 0.6 0.7 0.5 0.0 0.2 0.4 0.0 2.6 0.3 0.0 3.5 0.0 2.0 1.8 2.1 1.2 0.5 0.0 0.0 0.0 2.1 1.2 0.4 0.6 10.8 0.0 2.2 0.0 2.1 1.3 0.0 0.4 1.3 0.5 0.0 0.1 0.3 10.1 3.2 0.1 0.0 0.6 0.4 3.3 0.9 0.2 1.8 0.0 0.1 3.0 0.0 4.0 3.5 0.1 0.0 3.8 0.4 0.1 0.0 0.1 0.9 7.1 0.0 0.6 3.2 0.5 2.1 0.0 0.0 0.7 0.2 0.1 0.0 0.2 SHANK1 "SPANK-1, SSTRIP, synamon" ENSG00000161681 "SH3 and multiple ankyrin repeat domains 1" Q9Y566 19 50659255-50719802 "Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 71.1" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.7;Excitatory neurons: 29.6;Horizontal cells: 8.4;Inhibitory neurons: 32.9;Oligodendrocyte precursor cells: 7.1" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.2" "Group enriched" "Detected in many" 5 "amygdala: 20.6;basal ganglia: 28.8;cerebral cortex: 71.1;hippocampal formation: 36.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "REH: 5.2;THP-1: 2.4;U-138 MG: 2.7;U-2 OS: 7.3;U-87 MG: 2.9;U-937: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032129, HPA032130" Uncertain Supported "Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA032129: AB_10602796, HPA032130: AB_2674169" "unprognostic (1.62e-1)" "unprognostic (4.40e-2)" "unprognostic (7.83e-3)" "unprognostic (4.62e-2)" "unprognostic (1.70e-2)" "unprognostic (1.54e-1)" "unprognostic (1.76e-2)" "unprognostic (1.35e-2)" "unprognostic (5.02e-2)" "unprognostic (1.61e-1)" "unprognostic (7.51e-2)" "unprognostic (3.27e-1)" "unprognostic (3.65e-2)" "unprognostic (1.61e-2)" "unprognostic (5.14e-2)" "unprognostic (4.66e-3)" "unprognostic (1.29e-3)" 0.0 1.2 20.6 0.0 28.8 0.3 0.1 1.5 71.1 0.5 0.0 0.1 0.0 0.4 0.1 0.0 2.4 0.2 0.1 36.8 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.0 1.6 1.1 0.1 0.0 0.1 0.0 5.3 0.1 0.1 0.1 0.3 0.1 0.2 0.0 0.1 0.0 0.5 7.5 0.3 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.8 0.8 0.0 0.1 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.4 0.5 0.0 0.0 0.5 0.1 0.1 0.5 0.8 0.0 0.0 5.2 0.0 0.5 0.0 0.0 0.0 1.8 0.0 0.0 0.8 0.0 0.0 2.4 1.6 2.7 7.3 0.0 0.0 0.0 0.0 0.0 2.9 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.6 28.8 1.5 71.1 36.8 0.0 0.0 0.2 0.0 0.0 7.5 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 4.3 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.3 0.0 0.0 29.6 0.0 0.1 0.2 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.4 32.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.9 0.0 0.1 0.0 7.1 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SLC10A5 ENSG00000253598 "Solute carrier family 10 member 5" Q5PT55 8 81693631-81695058 "Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 3.9;liver: 11.3" "Cell type enhanced" "Detected in some" "Distal enterocytes: 4.1;Enteroendocrine cells: 3.6;Gastric mucus-secreting cells: 6.1;Hepatocytes: 2.8;Proximal enterocytes: 7.2;Respiratory ciliated cells: 4.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "OE19: 3.6" "Not detected" "Not detected" HPA025966 Uncertain Approved "Plasma membrane" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA025966: AB_1856959" "unprognostic (6.42e-2)" "unprognostic (3.89e-1)" "unprognostic (1.25e-2)" "unprognostic (2.34e-2)" "unprognostic (8.13e-3)" "unprognostic (1.91e-1)" "unprognostic (5.71e-2)" "unprognostic (5.63e-2)" "unprognostic (3.67e-1)" "unprognostic (2.41e-1)" "unprognostic (1.37e-1)" "unprognostic (3.22e-1)" "unprognostic (8.95e-2)" "unprognostic (2.51e-1)" "unprognostic (2.24e-1)" "unprognostic (1.67e-1)" "unprognostic (2.82e-7)" 0.1 0.2 0.9 0.3 0.9 0.0 0.2 1.8 1.4 0.3 0.0 2.8 3.2 0.3 0.7 0.3 0.3 1.7 0.2 0.8 0.9 1.8 11.3 0.2 0.0 0.6 0.7 0.3 1.0 0.2 1.0 0.0 0.7 0.6 3.7 0.5 0.3 0.2 0.2 0.4 3.9 0.2 0.2 0.3 3.4 0.1 1.0 0.1 0.5 0.3 0.2 0.3 0.2 0.8 0.2 0.2 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.2 0.1 0.2 0.1 0.4 0.5 0.0 0.0 0.2 0.3 0.1 0.2 0.2 0.8 0.6 1.3 0.5 0.1 0.0 0.1 0.1 0.6 0.2 0.8 0.6 0.1 0.2 0.5 0.3 0.3 0.2 0.2 0.4 0.0 3.6 0.2 0.0 0.1 0.2 0.2 1.4 0.5 0.3 0.1 0.2 0.1 0.1 0.5 0.1 0.3 0.3 0.5 0.4 0.5 0.3 0.9 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.9 1.8 1.4 0.8 0.9 0.6 0.7 0.7 0.2 1.0 0.8 0.2 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.0 0.3 0.3 0.3 0.6 0.0 0.5 0.0 0.0 0.0 0.0 4.1 1.9 0.4 0.0 0.4 0.3 0.2 3.6 0.0 0.9 1.1 0.1 0.1 6.1 0.3 0.0 0.3 0.7 2.8 0.0 0.0 0.8 1.5 2.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.5 1.9 0.0 0.0 0.4 7.2 1.7 4.1 0.2 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.5 2.4 0.5 SLC13A3 "NADC3, SDCT2" ENSG00000158296 "Solute carrier family 13 member 3" Q8WWT9 20 46557823-46684467 "Disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "kidney: 407.6" "Cell type enhanced" "Detected in many" "Astrocytes: 53.8;Cytotrophoblasts: 106.6;Excitatory neurons: 65.0;Oligodendrocytes: 178.1;Proximal tubular cells: 245.9;Syncytiotrophoblasts: 79.4" "Cancer enhanced" "Detected in many" "liver cancer: 11.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 16.1;EFO-21: 18.8;Hep G2: 56.1;HHSteC: 18.4;K-562: 15.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014333, HPA014353, HPA014736" Enhanced Supported "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA014333: AB_2732407, HPA014353: AB_1856968, HPA014736: AB_1856970" "unprognostic (1.07e-2)" "unprognostic (7.40e-2)" "unprognostic (5.59e-2)" "unprognostic (1.19e-2)" "unprognostic (3.34e-1)" "unprognostic (3.19e-2)" "unprognostic (2.15e-1)" "unprognostic (2.82e-2)" "unprognostic (1.66e-2)" "unprognostic (9.50e-2)" "unprognostic (1.92e-2)" "unprognostic (1.03e-1)" "unprognostic (8.94e-2)" "unprognostic (3.87e-1)" "unprognostic (1.17e-1)" "unprognostic (1.87e-1)" "unprognostic (2.05e-2)" 1.3 2.4 12.5 0.7 22.8 0.2 1.9 16.5 16.1 2.0 4.9 0.8 0.3 1.8 1.0 0.9 2.4 1.9 1.0 10.1 16.2 407.6 21.7 1.4 0.6 18.3 19.5 4.5 9.0 0.2 2.6 43.2 19.0 6.3 0.5 1.1 4.9 0.8 1.0 2.2 0.4 1.9 12.5 0.6 4.7 8.7 19.9 1.1 1.4 0.3 0.7 1.8 1.4 37.4 0.1 0.0 1.6 5.6 8.3 7.7 16.1 3.5 2.0 1.9 1.4 0.0 0.1 0.2 18.8 0.2 0.1 2.1 0.1 2.6 4.5 0.0 0.6 6.8 0.4 56.1 18.4 0.1 4.8 10.5 7.5 10.9 5.4 5.4 0.0 0.0 15.3 0.3 0.0 0.6 0.1 0.7 10.3 0.2 0.0 0.2 0.0 0.1 1.2 0.4 0.7 0.2 0.0 4.0 0.8 1.0 2.9 0.3 0.2 0.1 4.0 8.7 0.1 0.5 1.2 0.1 0.6 0.0 0.4 0.7 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.0 0.5 0.0 0.0 12.5 22.8 16.5 16.1 10.1 16.2 18.3 19.5 19.0 12.5 19.9 37.4 0.3 0.0 2.2 53.8 3.8 1.3 1.0 0.8 6.2 0.7 1.2 1.7 1.7 0.0 0.5 7.3 0.0 106.6 0.0 0.1 15.6 0.2 23.3 0.5 2.0 0.6 0.0 0.0 65.0 0.9 7.1 2.3 3.1 0.8 0.0 3.0 0.4 17.5 9.5 0.0 40.3 0.0 0.0 0.3 0.7 27.8 3.1 2.0 0.0 11.2 0.0 0.4 0.0 24.1 178.1 0.9 0.0 0.4 1.2 3.5 0.0 245.9 6.4 0.2 0.0 0.4 1.0 6.6 1.2 1.2 0.6 79.4 1.5 2.2 0.0 0.6 SLC14A1 "HsT1341, JK, RACH1, RACH2" ENSG00000141469 "Solute carrier family 14 member 1 (Kidd blood group)" Q13336 18 45687025-45752520 "Blood group antigen proteins, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 133.8;prostate: 78.3;urinary bladder: 90.9" "Group enriched" "Detected in many" 7 "Adipocytes: 136.6;Astrocytes: 228.5;Basal prostatic cells: 313.4;Erythroid cells: 102.5;Prostatic glandular cells: 192.6;Urothelial cells: 249.9" "Group enriched" "Detected in many" 5 "glioma: 5.3;prostate cancer: 8.6;urothelial cancer: 16.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 4.1" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "GAMG: 273.4;RT4: 113.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA059570, HPA077233" Approved Supported "Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" "HPA059570: AB_2684066, HPA077233: " "unprognostic (2.04e-1)" "unprognostic (2.56e-3)" "unprognostic (5.20e-2)" "unprognostic (1.27e-1)" "unprognostic (6.86e-2)" "unprognostic (1.84e-2)" "unprognostic (1.70e-2)" "unprognostic (7.97e-2)" "unprognostic (8.17e-2)" "unprognostic (9.99e-2)" "unprognostic (2.69e-1)" "unprognostic (1.42e-1)" "unprognostic (3.02e-2)" "unprognostic (2.31e-1)" "unprognostic (1.52e-1)" "unprognostic (9.09e-2)" "unprognostic (6.93e-2)" 3.4 1.6 70.2 1.0 97.1 15.2 2.0 110.5 53.6 3.6 24.9 1.7 1.3 0.5 0.7 0.4 0.3 10.1 23.7 60.5 96.0 37.9 1.1 4.3 2.3 109.4 131.0 0.3 1.7 0.9 1.0 1.6 114.2 78.3 1.3 0.3 2.3 3.0 3.9 4.1 3.4 0.5 97.7 4.6 1.8 0.2 133.8 7.7 6.4 7.8 2.3 90.9 2.2 104.6 0.0 0.4 0.0 0.1 0.0 0.2 0.7 0.4 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 273.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.2 0.1 0.2 0.0 0.0 0.0 0.0 38.3 0.0 0.2 0.0 0.2 0.3 0.1 0.9 0.3 0.0 0.3 0.2 0.0 0.0 0.2 3.0 113.8 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.8 0.5 0.9 0.1 4.1 0.2 0.1 2.7 1.3 1.3 0.0 0.0 1.1 0.8 0.0 0.0 0.3 0.9 0.9 0.0 0.3 0.2 1.5 0.0 0.9 0.0 0.1 4.1 0.6 70.2 97.1 110.5 53.6 60.5 96.0 109.4 131.0 114.2 97.7 133.8 104.6 136.6 0.0 0.6 228.5 3.1 0.3 313.4 0.1 0.6 0.3 5.4 1.5 10.9 5.7 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.2 0.6 0.0 0.1 28.7 0.0 102.5 0.6 0.2 0.1 3.8 0.0 0.1 0.0 0.2 21.4 0.3 0.1 0.0 0.7 0.2 18.3 0.6 0.3 0.4 0.0 2.0 12.4 5.6 0.1 0.0 5.2 3.5 0.7 0.3 0.0 1.2 2.1 192.6 0.0 0.0 0.0 0.2 0.0 1.7 3.7 0.1 0.2 0.2 0.4 0.0 6.1 0.1 0.0 249.9 SLC16A2 "AHDS, DXS128, MCT7, MCT8, MRX22, XPCT" ENSG00000147100 "Solute carrier family 16 member 2" P36021 X 74421493-74533917 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 40.7" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Hepatocytes: 63.7;Inhibitory neurons: 21.6;Oligodendrocyte precursor cells: 23.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 83.9;GAMG: 70.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA072719 Approved "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA072719: AB_2686552" "prognostic unfavorable (8.88e-5)" "unprognostic (2.48e-1)" "unprognostic (1.99e-1)" "unprognostic (2.90e-3)" "unprognostic (1.49e-1)" "unprognostic (1.58e-2)" "unprognostic (1.58e-3)" "unprognostic (2.47e-2)" "unprognostic (1.48e-1)" "unprognostic (2.54e-1)" "unprognostic (5.67e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.83e-4)" "unprognostic (2.15e-2)" "unprognostic (1.89e-1)" "unprognostic (6.89e-3)" "prognostic unfavorable (3.16e-4)" 13.8 24.7 4.6 4.8 5.8 0.0 5.4 1.7 5.7 9.4 1.2 7.0 3.3 10.3 1.7 2.9 9.3 6.0 10.4 7.7 4.9 7.9 40.7 7.5 0.9 5.6 3.9 12.8 5.5 11.7 9.8 9.2 1.8 6.2 1.8 1.1 5.0 5.8 2.7 2.5 3.1 6.9 3.5 1.2 4.7 0.9 8.1 5.7 12.6 3.7 1.8 6.6 6.2 3.0 8.4 10.4 7.2 43.1 20.8 11.1 0.0 83.9 29.7 38.2 20.6 0.1 0.9 0.0 1.3 37.5 70.8 1.7 1.1 40.2 22.1 6.1 3.6 0.0 0.0 0.0 1.5 0.0 0.0 16.5 9.5 19.3 23.3 14.6 0.1 0.1 0.0 0.0 9.1 0.0 0.5 2.7 27.2 0.0 7.8 17.4 19.9 0.0 18.0 0.1 1.9 12.0 9.6 50.2 0.3 2.5 0.6 1.1 0.0 32.5 8.8 35.7 41.9 0.0 0.0 0.0 34.7 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 5.8 1.7 5.7 7.7 4.9 5.6 3.9 1.8 3.5 8.1 3.0 5.6 0.0 0.6 22.2 0.2 0.8 4.3 2.4 0.6 5.7 4.3 3.4 4.5 8.6 2.9 3.7 0.0 5.7 0.1 0.0 3.9 4.3 0.1 0.3 9.8 6.1 8.4 0.0 14.5 2.4 4.9 11.8 0.5 0.5 2.5 1.7 3.6 63.7 1.0 3.3 21.6 0.3 0.0 1.3 0.8 1.2 15.2 0.1 3.6 15.9 0.6 6.2 0.0 23.1 7.1 4.6 0.0 20.7 0.1 5.1 0.4 4.7 2.4 1.5 13.1 9.7 5.6 0.1 0.1 0.9 1.3 2.1 0.4 1.4 0.2 4.9 SLC19A1 "FOLT, RFC1" ENSG00000173638 "Solute carrier family 19 member 1" P41440 21 45493572-45573365 "Cancer-related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 82.6" "Group enriched" "Detected in many" 5 "Cytotrophoblasts: 158.0;Syncytiotrophoblasts: 362.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 102.9" "Lineage enriched" "Detected in all" 6 "granulocytes: 102.9" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024802 Approved Approved "Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA024802: AB_10602892" "unprognostic (4.31e-3)" "prognostic unfavorable (4.15e-4)" "unprognostic (5.23e-2)" "unprognostic (2.02e-1)" "unprognostic (3.11e-1)" "unprognostic (3.04e-2)" "unprognostic (7.34e-2)" "unprognostic (2.87e-3)" "unprognostic (4.04e-2)" "unprognostic (4.09e-2)" "unprognostic (2.85e-1)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.07e-10)" "unprognostic (1.44e-1)" "unprognostic (2.31e-1)" "unprognostic (7.97e-5)" "unprognostic (3.10e-1)" 7.7 9.4 8.2 5.7 4.0 8.1 5.9 5.6 12.4 10.0 82.6 6.8 22.5 6.4 0.9 3.2 6.9 1.9 4.2 11.8 2.7 8.0 20.9 15.7 4.2 5.3 5.2 11.8 6.9 0.8 5.4 13.6 6.0 5.8 0.8 2.3 3.3 0.8 2.6 3.9 7.9 1.1 3.0 15.1 7.4 4.6 6.6 2.2 13.8 0.5 0.7 4.3 5.2 4.1 28.9 23.7 4.9 19.4 1.5 2.1 40.2 12.5 1.9 11.1 7.0 55.1 26.1 26.8 24.9 2.8 9.1 14.1 9.0 8.5 2.7 25.2 51.2 54.7 12.4 38.8 6.1 37.2 8.5 2.7 6.3 11.6 3.3 3.3 9.1 27.3 67.6 11.8 3.5 29.3 49.6 29.9 28.5 11.2 30.0 66.5 5.4 79.2 4.6 16.9 29.7 26.7 14.9 23.5 11.2 6.7 18.4 41.4 10.7 14.6 18.8 4.3 21.1 4.8 18.5 23.5 6.7 56.4 11.9 1.6 18.5 24.1 0.9 16.3 2.8 2.5 1.4 2.0 13.4 0.8 2.0 1.5 102.9 1.1 10.8 4.1 3.2 7.9 8.2 4.0 5.6 12.4 11.8 2.7 5.3 5.2 6.0 3.0 6.6 4.1 1.4 48.1 6.3 13.7 2.9 2.4 2.0 2.6 1.8 23.6 3.9 3.4 2.5 1.5 6.2 0.0 0.0 158.0 0.5 8.2 0.0 8.0 3.7 2.2 5.8 3.4 0.0 6.7 3.4 4.9 21.5 3.7 4.1 4.5 1.3 12.7 1.1 16.2 27.3 8.4 4.0 4.1 8.2 11.1 5.0 6.6 6.5 8.6 3.6 23.4 8.3 5.7 0.0 2.0 1.7 7.6 5.4 11.3 9.4 4.6 20.5 2.4 0.9 3.6 0.0 3.3 4.1 1.5 4.8 1.8 1.6 362.4 2.6 5.1 8.5 0.9 SLC1A5 "AAAT, ASCT2, M7V1, RDRC" ENSG00000105281 "Solute carrier family 1 member 5" Q15758 19 46774883-46788594 "FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Host-virus interaction, Symport, Transport" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 148.6;Erythroid cells: 143.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 95.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA035239, HPA035240" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA035239: AB_10670587, HPA035240: AB_10604092" "unprognostic (8.26e-3)" "unprognostic (6.38e-2)" "unprognostic (7.24e-2)" "unprognostic (7.94e-2)" "unprognostic (2.32e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.66e-8)" "unprognostic (2.08e-1)" "unprognostic (1.06e-2)" "unprognostic (9.82e-2)" "unprognostic (9.40e-3)" "unprognostic (9.57e-3)" "prognostic unfavorable (1.18e-7)" "unprognostic (1.28e-2)" "unprognostic (6.30e-2)" "unprognostic (1.06e-2)" "unprognostic (9.83e-2)" 97.2 15.9 5.8 29.6 6.5 60.9 77.7 6.6 6.1 57.4 6.1 50.1 16.2 39.1 98.0 98.0 48.9 36.5 26.4 5.9 8.5 45.6 8.1 65.3 27.9 15.8 11.1 45.8 73.2 2.9 24.5 46.9 13.3 98.6 42.4 1.4 120.5 77.0 8.5 55.7 36.2 33.0 9.5 40.4 55.5 40.3 9.8 19.9 14.1 10.7 30.3 109.6 83.0 11.5 179.6 323.6 76.3 116.1 194.7 164.3 180.0 249.6 283.0 183.2 264.1 296.1 197.1 194.8 118.9 624.2 105.2 281.1 224.9 296.9 135.5 130.1 203.7 324.3 115.1 281.9 501.3 228.2 182.9 268.6 727.3 215.5 541.1 61.3 98.9 255.0 348.9 500.1 99.5 304.5 105.4 611.1 134.0 636.5 140.9 117.8 86.5 282.7 104.2 384.8 117.3 86.0 123.4 331.8 275.4 58.8 191.6 296.6 74.1 109.4 174.1 86.4 205.7 308.0 325.3 164.0 206.3 281.0 274.3 0.1 36.1 2.9 14.1 55.0 11.4 17.8 8.0 9.9 50.2 8.1 1.9 6.0 1.0 21.0 66.3 95.8 15.5 27.8 5.8 6.5 6.6 6.1 5.9 8.5 15.8 11.1 13.3 9.5 9.8 11.5 63.6 0.0 17.3 0.0 31.1 57.7 148.6 95.9 64.9 0.2 52.0 43.1 20.3 21.5 41.2 0.0 0.0 80.8 86.3 44.6 3.9 38.5 27.0 2.6 32.9 29.0 10.7 143.3 0.6 65.7 129.3 48.0 21.9 2.7 29.2 20.9 29.6 0.7 38.4 0.0 0.8 111.3 40.7 21.6 34.7 14.0 19.0 39.8 19.6 3.7 26.0 0.6 12.3 0.0 0.6 43.4 74.8 19.5 68.6 59.0 6.5 23.1 13.0 0.8 6.6 15.8 44.0 35.9 4.0 69.0 28.3 24.4 38.7 6.1 62.9 100.0 SLC24A2 NCKX2 ENSG00000155886 "Solute carrier family 24 member 2" Q9UI40 9 19507452-19786928 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport, Vision" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 117.1" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 2710.1" "Group enriched" "Detected in some" 4 "breast cancer: 0.5;glioma: 1.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 2.6;SCLC-21H: 2.2;U-87 MG: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA079359 Supported "Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA079359: " "unprognostic (1.30e-1)" "unprognostic (8.57e-2)" "unprognostic (4.20e-1)" "unprognostic (1.05e-2)" "unprognostic (3.33e-2)" "unprognostic (1.48e-2)" "unprognostic (8.46e-2)" "unprognostic (8.37e-2)" "unprognostic (1.27e-1)" "unprognostic (1.50e-2)" "unprognostic (6.51e-2)" "unprognostic (1.57e-2)" "unprognostic (2.08e-4)" "unprognostic (1.58e-1)" "unprognostic (2.11e-3)" "unprognostic (1.51e-2)" 0.1 5.9 28.4 0.0 64.7 0.1 0.0 42.3 64.6 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.5 0.1 0.0 19.2 19.1 0.1 0.0 0.0 0.0 81.3 36.3 0.0 0.0 0.0 0.8 0.1 87.7 0.1 0.0 18.7 0.0 0.0 0.1 0.1 0.0 0.0 19.4 0.1 0.1 0.2 81.9 0.0 0.0 0.3 0.0 0.0 0.0 117.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.1 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.5 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.3 0.2 0.2 0.1 0.1 0.0 28.4 64.7 42.3 64.6 19.2 19.1 81.3 36.3 87.7 19.4 81.9 117.1 0.0 0.0 0.0 18.9 0.1 0.0 0.0 0.0 0.0 58.7 0.0 0.0 2.3 0.0 0.0 0.0 273.1 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.1 0.1 0.0 0.0 668.6 0.0 0.1 0.9 0.0 0.1 0.0 0.0 1.4 0.0 0.1 97.6 637.3 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 25.3 0.0 4.1 0.0 217.6 2710.1 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 10.4 0.0 3.2 0.2 0.2 0.7 0.0 0.1 0.3 0.0 0.0 0.1 0.0 SLC24A4 NCKX4 ENSG00000140090 "Solute carrier family 24 member 4" Q8NFF2 14 92322581-92501481 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Olfaction, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport" "Amelogenesis imperfecta, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "choroid plexus: 92.6" "Group enriched" "Detected in some" 4 "Bipolar cells: 251.6;Cone photoreceptor cells: 200.1" "Group enriched" "Detected in some" 5 "glioma: 0.5;melanoma: 0.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "classical monocyte: 11.1;intermediate monocyte: 14.7;non-classical monocyte: 11.6" "Lineage enriched" "Detected in many" 5 "monocytes: 14.7" "Cell line enhanced" "Detected in single" "SCLC-21H: 1.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063206 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA063206: " "unprognostic (1.53e-1)" "unprognostic (1.41e-1)" "unprognostic (2.22e-1)" "unprognostic (1.18e-1)" "unprognostic (1.06e-1)" "unprognostic (3.43e-3)" "unprognostic (1.34e-1)" "unprognostic (2.04e-3)" "unprognostic (3.40e-2)" "unprognostic (1.32e-1)" "unprognostic (2.48e-3)" "unprognostic (3.21e-1)" "unprognostic (1.48e-3)" "unprognostic (1.25e-1)" "unprognostic (1.08e-1)" "unprognostic (1.90e-2)" "unprognostic (1.58e-2)" 0.5 0.2 7.1 1.4 10.3 3.5 0.1 17.5 8.1 0.2 92.6 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.2 7.2 5.3 0.0 0.1 0.8 1.2 22.7 14.1 0.2 0.1 0.0 1.4 0.3 19.1 0.2 0.2 12.3 0.1 0.3 0.8 0.1 0.3 0.4 14.7 2.7 0.1 1.1 16.5 0.4 0.1 1.0 0.4 0.3 0.2 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 11.1 0.0 0.0 14.7 0.2 0.0 0.0 0.0 3.0 0.1 0.0 0.0 1.5 0.1 11.6 0.5 0.0 2.7 7.1 10.3 17.5 8.1 7.2 5.3 22.7 14.1 19.1 14.7 16.5 12.9 0.8 0.0 1.9 47.0 0.4 0.0 0.1 0.0 0.0 251.6 0.3 0.1 1.8 0.0 0.0 0.0 200.1 0.0 0.1 0.0 0.0 0.0 4.0 0.5 0.1 0.9 0.0 0.8 19.9 0.0 0.1 0.5 0.0 0.8 0.0 0.0 1.1 0.0 4.0 0.0 28.5 0.0 0.0 22.2 1.8 5.6 0.3 16.6 0.0 2.8 44.3 4.1 1.0 10.1 1.3 0.1 0.0 0.4 0.1 0.2 0.0 0.2 0.7 10.6 0.0 9.9 0.2 0.1 1.6 0.0 0.0 0.3 0.3 0.0 0.0 0.1 SLC2A1 "CSE, DYT18, DYT9, GLUT, GLUT1, HTLVR" ENSG00000117394 "Solute carrier family 2 member 1" P11166 1 42925353-42958893 "Cancer-related genes, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Cancer-related genes, Cataract, Disease variant, Dystonia, Epilepsy, Hereditary hemolytic anemia, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 98.7;skin 1: 79.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 833.8;Erythroid cells: 520.4;Extravillous trophoblasts: 536.4;Syncytiotrophoblasts: 2482.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 241.0;CACO-2: 219.9;Hep G2: 157.4" "Low region specificity" "Detected in all" "CAB002759, HPA031345, HPA058494" Enhanced Supported Enhanced "Plasma membrane" No No 2000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "CAB002759: , HPA031345: AB_2673835, HPA058494: AB_2683734" "unprognostic (3.60e-2)" "unprognostic (5.85e-3)" "unprognostic (7.59e-2)" "unprognostic (1.31e-2)" "unprognostic (4.10e-3)" "unprognostic (3.22e-2)" "prognostic unfavorable (3.65e-8)" "prognostic unfavorable (1.09e-4)" "unprognostic (1.10e-1)" "unprognostic (4.84e-2)" "prognostic unfavorable (4.39e-5)" "unprognostic (1.87e-1)" "prognostic unfavorable (4.55e-9)" "unprognostic (1.11e-1)" "unprognostic (9.49e-2)" "unprognostic (1.17e-1)" "prognostic unfavorable (4.05e-4)" 6.9 3.6 24.1 2.5 26.1 41.6 7.8 33.7 27.7 28.6 43.6 6.1 0.4 5.1 1.4 54.1 8.2 1.7 10.0 20.6 28.5 14.2 1.7 3.3 1.0 31.9 29.3 5.5 2.1 4.5 4.8 98.7 34.5 6.0 1.0 24.6 17.6 5.1 2.0 79.8 4.6 0.4 24.7 7.5 8.4 2.1 41.2 1.0 3.0 1.5 2.1 19.3 54.2 29.4 60.5 52.9 66.3 6.2 3.5 1.2 241.0 47.8 36.9 15.5 27.8 219.9 96.3 22.2 138.9 6.0 26.5 43.6 12.5 52.3 14.8 16.4 10.3 29.8 20.9 157.4 12.9 16.8 8.1 3.3 21.3 18.3 20.5 96.7 2.9 12.8 81.2 1.5 11.7 46.6 7.4 11.7 35.1 22.1 17.9 8.4 20.6 23.3 21.7 17.9 27.0 23.8 47.7 95.6 11.0 70.0 3.8 16.9 14.9 25.6 28.6 6.1 83.8 5.3 6.5 11.5 57.1 8.2 25.5 0.5 0.1 1.2 10.6 0.3 8.5 10.9 5.1 6.7 3.7 8.3 3.8 4.8 0.2 4.3 0.1 18.4 6.2 4.0 24.1 26.1 33.7 27.7 20.6 28.5 31.9 29.3 34.5 24.7 41.2 29.4 3.1 0.0 1.8 12.7 25.4 286.1 48.8 286.3 66.0 15.8 41.4 21.8 26.7 20.0 159.3 27.6 66.7 833.8 33.5 53.1 5.9 53.2 4.0 112.1 46.0 100.5 18.4 520.4 2.8 11.7 536.4 25.9 11.7 118.9 6.3 6.8 2.2 2.1 84.8 5.0 3.2 22.4 65.1 1.6 34.2 0.3 7.8 5.0 21.4 71.2 36.0 350.1 18.6 8.0 9.9 120.3 51.9 14.7 11.6 31.2 1.9 2.2 118.1 32.1 0.0 9.8 32.1 0.1 2.4 99.1 238.3 2482.5 20.8 5.5 11.8 105.8 SLC2A14 "GLUT14, SLC2A3P3" ENSG00000173262 "Solute carrier family 2 member 14" Q8TDB8 12 7812512-7891148 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Differentiation, Spermatogenesis, Sugar transport, Transport" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "testis: 81.3" "Cell type enriched" "Detected in many" 5 "Spermatocytes: 65.7" "Cancer enriched" "Detected in single" 35 "testis cancer: 7.1" "Region enhanced" "Detected in many" "cerebellum: 4.7" "Immune cell enhanced" "Detected in some" "basophil: 3.7;neutrophil: 3.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "BEWO: 18.4;CACO-2: 31.0;SuSa: 35.5" HPA006539 Supported Approved "Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 74: Testis - Spermatogenesis" "Cluster 39: CACO-2 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" "HPA006539: AB_1078984" "unprognostic (2.52e-1)" "unprognostic (4.74e-3)" "unprognostic (1.79e-1)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (1.82e-3)" "unprognostic (8.62e-2)" "unprognostic (7.15e-2)" "unprognostic (1.89e-1)" "unprognostic (9.91e-3)" "unprognostic (1.23e-1)" "unprognostic (1.27e-1)" "unprognostic (8.46e-4)" "unprognostic (3.92e-2)" "unprognostic (3.41e-1)" "unprognostic (3.26e-2)" "unprognostic (1.22e-2)" 0.8 5.7 0.7 0.3 0.9 6.2 0.9 4.7 1.0 0.2 1.8 0.9 0.2 0.2 0.2 1.5 0.4 0.9 0.7 1.5 0.9 0.6 3.0 0.5 0.5 0.2 0.1 2.7 6.6 0.0 0.4 1.1 0.5 1.2 0.5 1.4 0.1 0.1 0.5 0.7 0.5 0.5 0.0 0.3 0.2 81.3 1.3 0.2 0.2 0.1 0.2 1.0 0.3 0.5 0.4 1.5 0.7 0.4 0.3 0.8 18.4 0.2 0.0 0.0 0.5 31.0 0.2 0.1 0.8 0.0 0.3 0.2 0.1 0.0 0.0 0.7 0.2 3.3 1.2 8.1 0.1 2.0 4.5 0.0 0.2 0.2 0.0 0.1 0.0 1.1 3.6 0.8 0.0 0.7 0.4 1.6 3.6 0.1 0.0 0.2 0.1 1.1 0.0 0.5 0.6 0.2 0.5 0.7 0.1 35.5 0.1 2.7 0.5 0.1 3.0 0.5 0.5 3.0 1.3 0.6 0.9 0.1 0.6 3.7 0.4 1.0 0.6 0.1 0.6 0.3 0.5 0.4 0.2 0.3 0.3 0.4 3.4 0.6 0.1 0.2 1.0 0.2 0.7 0.9 4.7 1.0 1.5 0.9 0.2 0.1 0.5 0.0 1.3 0.5 2.1 0.0 1.1 0.0 0.9 0.6 0.0 0.0 0.0 0.1 0.1 0.3 2.4 0.0 0.0 0.0 4.2 0.4 0.5 0.1 0.0 0.0 8.9 0.1 1.3 3.2 0.0 6.9 1.9 1.5 1.5 1.9 0.0 0.2 9.5 6.4 5.3 0.5 0.2 0.0 2.2 0.0 0.0 2.5 12.2 5.4 0.3 1.4 1.8 1.9 0.0 0.1 0.0 0.5 0.4 0.3 5.7 2.6 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.2 2.7 65.7 3.1 0.0 0.1 0.4 3.6 4.2 0.1 0.0 SLC2A2 GLUT2 ENSG00000163581 "Solute carrier family 2 member 2" P11168 3 170996347-171026743 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "liver: 836.1" "Cell type enriched" "Detected in some" 4 "Hepatocytes: 457.6" "Cancer enriched" "Detected in some" 12 "liver cancer: 105.2" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 55 "CACO-2: 7.7;Hep G2: 27.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB010444, HPA028997" Enhanced Supported "Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "CAB010444: AB_641068, HPA028997: AB_2672860" "unprognostic (9.56e-2)" "unprognostic (1.24e-1)" "prognostic favorable (2.63e-5)" "unprognostic (3.10e-1)" "unprognostic (1.02e-1)" "unprognostic (2.95e-2)" "unprognostic (6.31e-2)" 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.2 0.4 0.0 0.2 0.0 66.1 0.0 0.0 0.0 0.0 5.2 0.0 0.3 0.3 30.8 836.1 0.0 0.0 0.5 0.4 0.0 2.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 48.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 27.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.2 0.4 0.3 0.3 0.5 0.4 0.8 0.4 0.4 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 90.1 0.0 0.0 0.0 0.0 0.0 0.1 1.9 0.2 6.7 0.0 0.0 0.1 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 457.6 0.0 0.0 0.1 3.0 0.0 10.0 0.0 1.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 2.5 0.0 0.0 0.0 105.4 63.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 1.8 0.0 SLC2A3 GLUT3 ENSG00000059804 "Solute carrier family 2 member 3" P11169 12 7919230-7936187 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 427.9" "Cell type enhanced" "Detected in many" "Adipocytes: 362.1;Endothelial cells: 356.2;Extravillous trophoblasts: 382.4;granulocytes: 485.1;Langerhans cells: 710.4;Macrophages: 305.2;T-cells: 328.9" "Cancer enriched" "Detected in all" 7 "testis cancer: 107.9" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "basophil: 166.1;neutrophil: 223.4" "Lineage enriched" "Detected in all" 9 "granulocytes: 223.4" "Group enriched" "Detected in many" 5 "BEWO: 1473.1;CACO-2: 1646.2;SuSa: 1119.9" "CAB002763, HPA006539" Approved Approved "Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 39: CACO-2 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB002763: , HPA006539: AB_1078984" "unprognostic (9.20e-2)" "unprognostic (9.63e-3)" "prognostic unfavorable (8.58e-4)" "unprognostic (2.65e-1)" "unprognostic (5.29e-3)" "unprognostic (2.16e-3)" "unprognostic (1.12e-1)" "unprognostic (8.27e-2)" "unprognostic (2.35e-1)" "unprognostic (3.83e-2)" "unprognostic (8.47e-3)" "unprognostic (5.40e-2)" "prognostic unfavorable (6.36e-8)" "prognostic unfavorable (2.89e-5)" "unprognostic (1.70e-1)" "unprognostic (1.14e-2)" "unprognostic (2.91e-3)" 124.9 19.3 26.3 58.2 28.4 427.9 77.0 26.0 38.3 16.4 26.4 29.6 6.7 20.8 2.0 12.7 27.4 56.1 62.3 33.3 31.6 37.7 28.0 92.8 29.4 28.9 25.6 26.4 11.2 7.9 28.0 102.8 33.0 19.7 12.7 87.3 12.3 5.6 24.1 20.7 15.7 41.5 24.6 45.7 19.8 4.9 31.1 18.4 43.3 10.0 20.8 98.7 26.2 23.3 0.3 7.9 68.5 27.4 25.2 85.9 1473.1 24.7 26.7 23.9 55.9 1646.2 11.0 1.6 0.0 17.1 33.1 0.6 2.4 3.9 43.0 48.4 2.0 96.3 6.5 219.3 67.3 35.0 135.4 36.2 2.8 63.6 28.5 55.8 22.6 7.5 44.8 22.8 21.9 0.1 2.6 38.4 300.9 1.2 0.0 2.1 8.0 1.4 0.1 0.1 0.3 0.6 0.0 2.4 32.8 1119.9 0.0 4.9 23.1 29.7 15.6 57.4 2.5 0.2 68.8 5.2 86.9 15.9 16.6 166.1 19.3 29.7 25.3 2.3 20.2 7.4 16.9 19.5 10.0 7.0 10.8 14.8 223.4 15.6 1.0 0.8 24.9 17.4 26.3 28.4 26.0 38.3 33.3 31.6 28.9 25.6 33.0 24.6 31.1 23.3 362.1 144.2 98.8 5.5 301.0 129.5 3.5 1.7 8.6 33.0 5.1 7.6 21.0 7.2 26.8 3.7 62.6 69.6 112.1 0.2 0.0 0.2 3.1 5.0 84.3 356.2 1.2 13.7 24.4 0.0 382.4 188.9 12.2 4.3 485.1 6.5 96.4 2.4 113.4 5.0 20.8 0.3 0.0 76.4 710.4 3.1 10.2 305.2 183.2 34.7 43.4 28.5 41.2 6.6 5.0 0.7 1.3 7.9 93.2 5.3 0.1 1.4 10.3 70.2 118.3 21.5 187.1 2.4 1.2 4.9 82.0 111.4 328.9 41.7 0.1 4.0 SLC2A5 GLUT5 ENSG00000142583 "Solute carrier family 2 member 5" P22732 1 9035106-9088478 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 97.3;intestine: 109.1;skeletal muscle: 78.8;testis: 76.4" "Cell type enhanced" "Detected in many" "Early spermatids: 64.3;Paneth cells: 55.6;Plasma cells: 35.3;Proximal enterocytes: 189.4;Spermatocytes: 83.2" "Group enriched" "Detected in many" 6 "glioma: 11.0;renal cancer: 11.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "naive B-cell: 23.3" "Lineage enriched" "Detected in many" 5 "B-cells: 23.3" "Group enriched" "Detected in some" 5 "Daudi: 190.3;THP-1: 47.8;U-266/70: 154.0;U-698: 178.2;U-937: 68.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA005449, HPA075145" Enhanced Enhanced "Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA005449: AB_1078985, HPA075145: " "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (8.00e-3)" "unprognostic (2.25e-2)" "unprognostic (6.13e-2)" "unprognostic (2.61e-1)" "unprognostic (1.47e-2)" "unprognostic (5.35e-2)" "unprognostic (4.18e-1)" "unprognostic (6.85e-2)" "unprognostic (3.77e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.44e-5)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (8.19e-3)" "unprognostic (8.61e-2)" 7.7 3.4 9.2 5.4 9.2 97.3 5.1 10.5 11.8 2.6 10.1 4.8 109.1 1.3 10.5 3.9 2.6 1.1 2.3 10.3 12.0 38.4 0.6 1.2 20.4 24.1 14.5 2.8 0.6 1.5 2.9 4.9 20.4 15.1 3.6 2.7 2.4 5.1 78.8 6.9 85.3 4.4 14.3 5.6 0.9 76.4 16.1 1.7 0.8 65.9 18.3 3.0 4.2 19.6 0.3 0.1 0.0 0.2 0.2 1.2 0.5 0.2 0.7 0.0 0.6 1.3 0.0 190.3 0.2 0.4 0.1 0.4 1.7 0.1 0.4 25.1 0.2 0.2 3.4 0.0 0.3 3.0 1.6 2.7 2.6 0.6 0.0 2.9 0.0 0.1 0.3 2.0 0.0 0.0 0.1 10.0 0.2 0.0 0.2 4.9 0.0 5.9 0.2 2.0 0.6 0.3 0.3 0.5 0.7 0.1 0.3 47.8 0.2 3.0 0.9 0.5 0.2 154.0 0.2 178.2 0.2 68.2 0.2 4.8 2.5 0.2 0.2 0.5 0.2 4.3 0.2 0.2 0.9 23.3 0.2 0.2 1.4 0.3 0.1 0.2 0.1 1.2 9.2 9.2 10.5 11.8 10.3 12.0 24.1 14.5 20.4 14.3 16.1 19.6 0.3 0.0 0.0 2.0 5.2 2.0 2.0 0.2 10.2 0.0 0.1 0.4 1.9 0.0 0.0 1.8 0.0 0.1 0.0 1.4 7.9 0.3 64.3 0.1 0.3 4.9 1.2 0.0 1.0 0.0 1.1 0.8 0.0 0.4 1.3 0.1 0.4 0.1 4.3 0.0 1.2 7.6 0.0 0.8 1.2 19.3 2.8 2.7 0.0 31.9 0.6 0.6 0.0 2.5 0.9 0.6 55.6 0.4 35.3 2.1 189.4 24.2 0.0 0.1 6.6 2.1 0.4 83.2 8.2 2.7 0.6 0.5 0.3 0.3 8.0 0.2 SLC35F5 FLJ22004 ENSG00000115084 "Solute carrier family 35 member F5" Q8WV83 2 113705011-113756693 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034828, HPA049229" Uncertain Uncertain "Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "HPA034828: AB_2674350, HPA049229: AB_2680682" "unprognostic (1.59e-2)" "prognostic unfavorable (2.60e-4)" "unprognostic (8.37e-2)" "unprognostic (3.87e-3)" "unprognostic (5.62e-2)" "unprognostic (4.73e-3)" "unprognostic (3.94e-2)" "unprognostic (5.68e-2)" "unprognostic (1.19e-1)" "unprognostic (1.63e-2)" "unprognostic (1.93e-2)" "unprognostic (1.77e-1)" "prognostic favorable (1.71e-5)" "unprognostic (1.64e-1)" "unprognostic (1.84e-1)" "unprognostic (2.33e-1)" "unprognostic (4.83e-2)" 9.8 22.8 4.6 6.0 5.9 8.0 14.3 12.0 6.6 9.3 31.5 14.7 13.7 10.3 11.5 11.1 8.0 11.1 11.0 6.1 6.4 18.0 14.6 9.9 9.0 6.7 4.8 12.4 15.1 17.4 5.2 11.1 7.1 11.2 13.6 14.1 9.8 6.9 12.3 20.3 12.9 8.9 5.4 10.1 12.9 7.1 5.2 5.7 23.7 11.2 10.0 8.0 6.3 12.0 9.7 9.6 7.7 4.9 48.6 36.8 14.0 15.9 13.2 7.7 12.9 24.3 18.9 18.5 22.1 21.9 21.3 8.7 12.2 12.5 17.9 5.7 4.9 9.7 9.6 19.7 20.8 12.8 24.0 46.8 17.4 17.9 25.9 22.1 15.2 4.6 7.7 11.2 19.1 8.5 5.6 14.0 3.6 15.0 5.2 6.5 13.1 9.7 52.5 15.8 2.1 6.0 12.9 14.5 11.5 12.8 9.4 12.6 12.7 14.3 6.3 9.2 6.7 9.7 8.7 8.2 16.8 8.9 13.6 2.9 0.7 0.6 0.5 0.8 0.6 0.9 0.5 0.4 0.6 1.2 0.6 0.6 2.1 1.0 1.2 0.9 0.9 0.6 4.6 5.9 12.0 6.6 6.1 6.4 6.7 4.8 7.1 5.4 5.2 12.0 18.9 22.4 19.8 39.5 18.0 25.4 31.1 20.0 31.9 10.3 20.4 9.8 25.4 21.5 30.4 73.5 22.9 46.3 11.6 44.1 11.7 28.7 28.3 32.4 21.9 15.4 14.5 9.9 43.4 28.5 72.0 24.8 28.5 38.6 24.1 14.4 12.5 20.8 28.3 5.0 47.0 25.6 12.2 13.4 17.2 15.6 12.5 14.6 8.8 39.4 15.5 21.0 7.2 65.4 83.2 23.1 29.7 13.9 37.5 35.3 47.9 45.1 26.3 19.6 0.0 14.2 22.7 60.0 20.5 32.7 34.0 66.4 10.8 41.0 24.8 35.1 SLC35G2 "DKFZp564K2464, MGC3295, TMEM22" ENSG00000168917 "Solute carrier family 35 member G2" Q8TBE7 3 136818647-136855888 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 54.2;Early spermatids: 65.4;Inhibitory neurons: 42.4;Spermatocytes: 35.5" "Cancer enhanced" "Detected in many" "glioma: 6.2" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "memory CD8 T-cell: 1.0" "Lineage enriched" "Detected in single" 10 "T-cells: 1.0" "Cell line enhanced" "Detected in many" "BJ hTERT+: 73.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA052054, HPA064728" Approved Supported "Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA052054: AB_2681709, HPA064728: AB_2685336" "unprognostic (1.04e-1)" "unprognostic (1.46e-2)" "unprognostic (6.91e-4)" "unprognostic (2.56e-4)" "unprognostic (5.34e-2)" "unprognostic (6.73e-2)" "unprognostic (1.16e-5)" "unprognostic (1.83e-3)" "unprognostic (1.12e-1)" "unprognostic (6.39e-2)" "unprognostic (1.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-7)" "unprognostic (1.00e-2)" "unprognostic (1.69e-1)" "unprognostic (1.07e-2)" "unprognostic (2.30e-2)" 14.9 15.4 20.9 2.1 21.2 0.5 11.1 23.1 26.4 5.1 16.5 3.8 1.0 4.3 4.6 2.6 5.7 5.3 8.1 20.0 24.4 3.9 4.4 7.0 1.9 21.4 25.0 5.5 7.6 6.7 19.3 7.4 26.9 4.1 2.0 5.3 3.1 2.6 2.4 3.7 2.9 5.1 22.1 3.2 2.9 14.4 22.6 2.8 8.5 5.4 1.2 6.5 5.0 21.0 3.9 10.7 10.6 4.8 20.8 17.1 0.0 16.9 73.1 24.7 37.0 10.1 5.7 0.0 12.7 17.5 39.3 1.3 12.7 0.7 22.8 0.1 3.5 3.2 12.0 6.3 26.6 0.1 0.0 24.2 1.8 21.5 5.9 18.0 18.8 6.8 1.8 0.1 32.1 0.0 4.7 3.3 2.3 0.0 7.9 4.2 7.1 0.2 21.1 0.9 17.5 11.7 13.7 0.0 24.0 3.6 0.0 1.8 13.1 18.4 4.7 8.2 18.6 0.0 0.0 0.0 25.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.1 20.9 21.2 23.1 26.4 20.0 24.4 21.4 25.0 26.9 22.1 22.6 21.0 22.4 12.8 7.0 54.2 2.5 3.3 4.9 12.0 7.4 4.7 0.7 0.8 2.5 1.5 7.1 1.8 12.5 1.3 2.7 0.8 1.9 3.3 65.4 1.0 1.6 30.6 4.2 4.4 34.0 10.7 1.3 12.4 0.5 1.3 2.5 3.6 27.8 2.3 0.7 6.7 42.4 1.0 0.0 2.2 7.3 30.3 9.9 2.1 3.6 17.8 3.7 7.8 15.5 15.6 6.1 10.0 0.1 3.0 3.7 4.7 0.6 0.7 1.4 4.6 6.6 4.7 4.8 35.5 16.1 1.2 3.0 2.2 3.8 3.1 0.6 2.0 SLC38A2 "ATA2, KIAA1382, SAT2, SNAT2" ENSG00000134294 "Solute carrier family 38 member 2" Q96QD8 12 46358188-46372773 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Ion transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 1118.3;Suprabasal keratinocytes: 1078.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-HME1: 1198.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035180, HPA069672" Approved Supported "Plasma membrane" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 85: Liver - Metabolism" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "HPA035180: AB_10669901, HPA069672: " "unprognostic (6.61e-3)" "unprognostic (2.87e-2)" "unprognostic (4.88e-2)" "unprognostic (2.51e-2)" "unprognostic (2.96e-1)" "unprognostic (1.00e-2)" "unprognostic (7.78e-2)" "unprognostic (5.50e-3)" "unprognostic (1.20e-1)" "unprognostic (3.79e-1)" "unprognostic (9.24e-3)" "unprognostic (1.75e-1)" "unprognostic (1.47e-1)" "unprognostic (5.08e-2)" "unprognostic (3.80e-1)" "unprognostic (1.83e-1)" "unprognostic (8.68e-2)" 112.8 113.0 36.1 71.6 48.5 95.4 88.5 53.9 50.2 91.7 25.8 58.3 33.6 92.9 38.6 108.1 83.6 131.3 60.7 32.4 46.1 64.8 307.3 117.0 67.1 52.2 42.7 130.1 74.7 91.5 27.9 162.1 53.5 52.8 49.7 27.0 77.2 43.1 108.5 204.4 54.4 115.8 44.2 75.3 63.0 25.4 44.2 100.4 63.1 174.7 78.1 98.9 88.0 73.0 83.7 179.9 157.6 444.1 356.7 347.7 118.1 382.8 921.2 313.0 254.0 108.2 151.2 0.1 504.2 627.9 215.3 271.1 107.9 335.1 299.1 67.0 61.0 105.8 208.7 339.9 548.8 88.0 108.7 357.2 718.4 199.5 1198.9 778.5 265.7 116.3 103.8 163.1 560.4 100.0 110.3 122.8 138.2 0.1 185.1 97.5 115.5 200.9 191.6 173.4 103.9 89.8 263.5 68.5 233.7 171.0 140.5 193.8 467.3 156.7 121.8 67.8 62.2 187.8 194.3 100.6 148.0 304.5 76.8 41.1 24.9 18.9 22.7 13.1 17.4 19.2 19.0 23.0 35.2 17.8 23.5 24.8 17.5 51.6 18.4 40.6 23.7 27.6 36.1 48.5 53.9 50.2 32.4 46.1 52.2 42.7 53.5 44.2 44.2 73.0 237.7 83.3 77.4 31.3 187.7 1118.3 134.1 262.8 653.9 40.5 315.7 252.2 153.6 108.7 123.9 57.0 70.9 53.8 292.3 114.6 5.9 41.2 5.5 228.5 245.0 234.7 76.7 109.0 54.6 51.1 49.3 219.1 328.2 464.0 81.6 138.3 227.7 265.9 54.0 53.8 58.9 175.0 130.2 143.3 303.6 12.4 263.2 193.8 250.8 59.0 52.6 74.3 70.0 42.3 136.2 79.4 83.5 85.0 322.2 181.7 67.4 24.4 50.3 68.7 282.7 184.8 339.5 6.7 15.5 532.6 1078.3 38.4 252.4 84.0 110.7 150.8 SLC41A3 FLJ20473 ENSG00000114544 "Solute carrier family 41 member 3" Q96GZ6 3 126006357-126101561 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045847 Approved Supported "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA045847: AB_2679472" "unprognostic (1.77e-1)" "unprognostic (3.35e-2)" "unprognostic (1.11e-1)" "unprognostic (3.37e-2)" "unprognostic (7.68e-3)" "unprognostic (2.20e-1)" "prognostic unfavorable (1.49e-7)" "unprognostic (1.36e-1)" "unprognostic (3.23e-2)" "unprognostic (2.82e-3)" "unprognostic (5.74e-2)" "unprognostic (3.57e-1)" "prognostic favorable (6.04e-7)" "unprognostic (1.26e-1)" "unprognostic (5.88e-2)" "unprognostic (2.85e-1)" "unprognostic (7.54e-2)" 29.5 47.2 53.3 13.3 55.6 11.3 29.5 55.0 56.1 42.4 53.0 24.8 18.1 44.4 55.1 22.2 40.2 28.6 34.3 57.7 54.9 27.7 14.3 21.4 18.1 56.8 54.0 54.5 32.7 34.9 40.0 19.7 59.6 23.1 19.2 25.7 31.1 23.7 61.8 24.6 23.8 29.4 49.8 19.6 27.8 44.7 54.7 34.4 32.0 47.9 19.3 28.9 29.6 48.4 43.7 17.4 28.5 24.1 78.7 45.3 42.4 24.4 42.1 32.9 39.0 23.3 38.7 31.4 44.8 48.9 35.7 33.3 10.8 42.1 29.0 31.1 32.0 17.2 32.1 34.2 65.3 31.4 18.4 44.0 50.8 20.0 41.1 48.7 46.5 38.2 14.7 26.2 44.0 22.2 35.1 25.7 21.7 57.4 26.3 18.6 29.3 43.5 39.6 31.6 22.1 23.8 37.8 12.3 104.0 26.6 12.2 41.9 32.2 30.8 23.2 47.1 28.0 19.4 17.2 15.8 27.7 14.0 28.9 13.0 6.3 4.6 12.0 9.4 9.6 9.4 11.1 12.2 9.8 9.0 9.6 9.1 1.2 14.9 6.1 9.6 21.8 6.1 53.3 55.6 55.0 56.1 57.7 54.9 56.8 54.0 59.6 49.8 54.7 48.4 25.6 16.0 10.9 9.8 13.5 13.8 22.3 24.9 20.5 15.4 22.9 23.5 14.4 32.9 20.5 22.0 4.2 34.6 14.6 7.5 3.9 35.8 36.7 34.1 15.3 28.5 21.1 5.0 17.0 24.7 36.1 19.7 11.7 17.9 5.7 21.2 35.0 7.2 16.1 28.6 20.7 12.1 30.5 12.8 10.3 14.7 37.6 8.6 14.2 15.0 13.5 25.9 7.2 11.6 8.0 24.3 6.8 54.9 10.3 15.3 14.7 12.6 14.8 12.1 26.3 23.1 20.7 16.7 45.4 18.2 15.3 25.3 17.7 42.4 15.6 19.0 SLC45A4 KIAA1126 ENSG00000022567 "Solute carrier family 45 member 4" Q5BKX6 8 141207166-141308305 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Collecting duct cells: 49.7;Cone photoreceptor cells: 54.2;Endometrial ciliated cells: 57.6;Glandular and luminal cells: 97.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 7 "eosinophil: 8.3;neutrophil: 7.0" "Lineage enriched" "Detected in single" 22 "granulocytes: 8.3" "Cell line enhanced" "Detected in many" "HMC-1: 18.3;OE19: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023154 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 43: Testis - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA023154: AB_2191204" "unprognostic (7.79e-3)" "unprognostic (1.06e-1)" "unprognostic (4.30e-2)" "unprognostic (1.44e-1)" "unprognostic (6.06e-2)" "unprognostic (3.96e-2)" "unprognostic (1.26e-1)" "unprognostic (4.49e-3)" "unprognostic (1.02e-1)" "unprognostic (5.31e-2)" "unprognostic (2.12e-1)" "unprognostic (1.84e-1)" "prognostic favorable (1.73e-6)" "unprognostic (8.79e-3)" "unprognostic (1.13e-1)" "unprognostic (1.77e-2)" "unprognostic (2.40e-2)" 3.5 2.5 3.8 3.7 4.8 5.8 2.9 1.2 16.6 7.1 14.7 4.4 2.3 4.3 1.5 3.3 7.1 2.7 6.6 5.1 1.5 10.2 0.9 6.7 2.7 6.6 1.0 3.1 7.9 2.5 14.9 5.0 6.6 6.6 1.6 5.4 7.8 5.3 4.6 5.7 4.1 1.7 0.7 4.8 12.5 13.7 2.2 2.3 5.8 1.4 2.0 3.4 2.8 6.1 4.6 9.8 3.7 5.9 0.3 0.3 16.1 2.5 1.5 2.2 1.7 6.4 12.2 0.9 11.8 1.0 3.1 3.7 2.1 1.2 1.0 7.2 3.3 2.7 3.1 0.0 1.7 1.1 18.3 0.8 1.9 1.6 0.9 0.5 1.5 5.0 5.6 0.7 0.8 11.9 11.0 2.5 4.7 30.8 4.1 3.3 0.2 3.1 8.9 7.9 5.5 4.6 2.7 0.8 4.5 2.6 1.9 7.2 0.8 0.0 2.4 3.8 4.9 3.9 12.7 1.3 2.1 4.3 4.0 1.1 0.1 8.3 0.1 0.1 0.1 0.0 0.1 0.3 0.1 0.0 0.1 0.1 7.0 0.2 0.1 0.3 0.2 0.1 3.8 4.8 1.2 16.6 5.1 1.5 6.6 1.0 6.6 0.7 2.2 6.1 3.3 9.6 12.7 6.5 3.0 2.7 6.6 3.6 5.2 33.1 6.4 5.8 13.5 15.7 8.9 49.7 54.2 8.7 7.5 14.7 0.0 9.3 12.5 57.6 10.8 3.4 2.4 0.0 29.0 2.7 0.8 2.9 37.2 97.1 1.3 1.8 1.1 0.0 6.7 3.3 21.7 7.7 8.2 2.5 3.3 5.9 2.1 8.6 3.6 7.5 1.8 4.3 5.2 6.6 0.9 7.8 4.5 2.2 5.3 6.0 3.7 3.2 22.3 9.2 0.0 1.5 3.2 5.7 2.6 4.4 2.4 16.3 4.6 4.0 5.1 11.3 SLC4A8 NBC3 ENSG00000050438 "Solute carrier family 4 member 8" Q2Y0W8 12 51391317-51515763 "Metabolic proteins, Predicted membrane proteins, Transporters" "Anion exchange, Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 24.1;pituitary gland: 17.9;retina: 11.1;testis: 11.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 92.6;Cone photoreceptor cells: 179.3;Excitatory neurons: 115.0;Horizontal cells: 116.1;Inhibitory neurons: 127.8;Oligodendrocytes: 248.9;Spermatocytes: 91.9" "Group enriched" "Detected in some" 6 "breast cancer: 1.7;glioma: 2.7;testis cancer: 4.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 21.0;HMC-1: 14.8;SCLC-21H: 15.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077895 Approved "Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 77: Retina - Visual perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA077895: " "unprognostic (4.01e-1)" "unprognostic (8.15e-2)" "unprognostic (2.49e-2)" "unprognostic (6.39e-2)" "unprognostic (1.29e-1)" "unprognostic (1.96e-2)" "unprognostic (3.46e-2)" "unprognostic (7.72e-4)" "unprognostic (3.13e-2)" "unprognostic (7.03e-3)" "unprognostic (1.07e-4)" "unprognostic (1.70e-1)" "unprognostic (9.60e-6)" "unprognostic (1.35e-1)" "unprognostic (2.57e-1)" "unprognostic (3.21e-2)" "unprognostic (2.47e-1)" 0.2 3.1 6.7 0.9 7.5 0.6 1.3 10.3 18.1 1.1 0.0 0.4 0.4 0.3 2.5 0.1 1.7 0.3 0.3 9.8 10.6 1.9 0.1 1.2 1.4 23.3 8.6 3.3 1.0 2.2 17.9 0.2 24.1 0.4 0.4 11.1 0.9 0.6 0.1 0.2 0.8 0.3 3.6 1.0 1.3 11.7 9.0 0.6 0.2 0.0 1.2 0.2 0.1 11.4 0.2 1.0 11.9 0.1 0.5 0.6 21.0 3.3 5.5 5.2 3.3 7.2 0.2 4.5 0.5 4.5 2.9 0.1 4.7 0.2 4.8 0.9 0.6 2.3 0.3 0.0 0.0 0.7 14.8 0.2 0.2 2.7 0.5 3.1 6.2 1.9 0.1 7.6 2.7 2.6 6.6 1.4 5.1 1.4 3.6 0.1 0.0 0.0 0.6 0.1 15.7 10.7 1.3 1.6 0.0 3.6 2.0 0.5 5.7 3.3 1.7 0.2 4.3 3.8 1.3 0.2 4.6 0.6 0.4 0.4 0.5 0.9 0.4 0.3 0.0 0.1 0.1 0.4 0.7 0.2 0.1 0.2 0.5 0.5 0.8 0.2 0.0 0.2 6.7 7.5 10.3 18.1 9.8 10.6 23.3 8.6 24.1 3.6 9.0 11.4 1.2 0.0 8.7 33.6 3.1 0.0 0.8 0.2 0.0 92.6 5.0 1.5 1.9 0.0 5.4 1.8 179.3 1.4 4.9 0.5 7.9 0.1 61.9 1.7 0.6 2.4 6.0 0.8 115.0 1.3 5.2 2.1 13.3 0.7 7.6 11.5 1.1 0.2 2.2 116.1 127.8 0.4 0.0 4.7 2.2 32.8 2.8 4.5 1.8 18.7 3.4 11.5 7.2 20.1 248.9 0.1 5.4 3.8 3.5 1.0 1.9 1.0 25.0 19.9 0.0 0.7 1.0 91.9 8.2 0.1 0.1 0.4 4.3 0.9 0.2 1.1 SLC5A3 "SMIT, SMIT1" ENSG00000198743 "Solute carrier family 5 member 3" P53794 21 34073578-34106260 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 96.0" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 129.1;Collecting duct cells: 138.0;Granulosa cells: 148.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 22.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029791 Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" "HPA029791: AB_10601892" "unprognostic (9.70e-2)" "unprognostic (4.99e-2)" "unprognostic (2.23e-1)" "unprognostic (7.57e-2)" "unprognostic (1.07e-1)" "unprognostic (4.54e-2)" "unprognostic (4.48e-3)" "unprognostic (1.63e-1)" "unprognostic (3.02e-2)" "unprognostic (2.55e-1)" "prognostic unfavorable (1.98e-5)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.72e-4)" "unprognostic (1.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.21e-1)" "unprognostic (8.60e-2)" 6.9 5.9 8.6 4.5 9.2 1.9 6.6 5.7 11.4 3.7 96.0 4.5 2.6 6.8 5.2 3.1 4.8 2.5 2.4 10.7 17.0 29.0 5.9 3.9 4.9 9.3 9.9 3.9 1.9 3.2 4.1 10.6 9.2 2.9 5.2 5.6 2.8 3.5 2.5 6.7 3.7 2.9 8.2 2.4 3.9 6.2 20.3 3.9 25.2 2.6 4.8 3.8 3.4 9.2 10.5 9.3 19.0 13.4 15.5 12.7 9.1 11.8 35.7 7.2 10.9 15.5 22.5 16.9 9.3 24.0 13.5 5.3 23.3 6.7 12.2 17.7 6.0 17.5 9.0 5.2 4.1 7.6 7.1 6.1 17.0 19.7 7.8 22.0 4.4 13.7 17.6 3.9 18.7 7.1 8.1 6.1 9.6 4.0 9.0 8.1 3.4 7.7 28.1 14.5 9.9 4.6 24.5 6.4 5.6 11.3 3.9 8.0 4.2 14.0 10.7 27.1 4.8 20.1 18.5 12.4 28.2 10.9 9.6 0.0 0.2 0.0 0.6 0.2 0.5 0.1 0.3 0.4 0.2 0.1 0.4 0.6 0.1 0.2 0.1 0.5 0.1 0.1 8.6 9.2 5.7 11.4 10.7 17.0 9.3 9.9 9.2 8.2 20.3 9.2 18.8 16.0 10.2 0.0 33.3 0.0 46.5 0.0 129.1 33.8 37.4 34.9 11.4 10.0 13.0 138.0 20.9 27.4 43.0 39.1 21.5 4.0 9.0 38.7 59.9 16.4 49.3 17.0 0.0 5.5 19.7 42.3 18.3 42.5 41.3 148.6 5.0 20.7 15.2 37.0 0.0 69.3 0.0 14.4 0.0 7.2 6.5 41.0 0.0 0.0 23.3 6.7 16.5 0.0 0.0 7.6 49.7 20.7 54.1 88.4 16.3 9.4 8.7 20.9 13.1 15.4 33.7 14.8 18.5 39.7 0.0 28.2 48.3 14.0 36.3 69.5 SLC5A6 SMVT ENSG00000138074 "Solute carrier family 5 member 6" Q9Y289 2 27199587-27212958 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 104.0" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 119.1;Extravillous trophoblasts: 111.7;Hepatocytes: 67.7;Syncytiotrophoblasts: 227.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BEWO: 310.9;SK-BR-3: 337.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036958 Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "HPA036958: AB_10672343" "unprognostic (5.85e-2)" "unprognostic (8.32e-3)" "unprognostic (1.38e-1)" "unprognostic (2.61e-3)" "unprognostic (9.38e-2)" "unprognostic (7.14e-2)" "unprognostic (3.20e-3)" "unprognostic (7.92e-2)" "unprognostic (6.96e-2)" "unprognostic (9.80e-2)" "unprognostic (2.05e-2)" "unprognostic (7.46e-2)" "prognostic unfavorable (3.60e-7)" "unprognostic (2.40e-3)" "unprognostic (1.20e-2)" "unprognostic (4.56e-3)" "unprognostic (4.18e-2)" 42.4 8.6 27.5 14.2 25.2 18.1 31.5 24.0 30.6 9.4 46.2 13.0 20.9 14.3 67.4 10.9 11.5 7.5 7.7 23.4 23.9 8.5 104.0 7.9 13.8 24.0 24.4 10.2 11.6 9.8 8.0 39.1 25.9 9.3 12.7 6.4 12.5 11.1 17.0 10.0 15.3 9.7 23.9 9.1 10.1 23.4 30.6 11.6 8.0 8.8 26.5 11.3 8.8 21.9 78.9 79.6 49.9 66.1 45.4 16.5 310.9 28.1 19.1 41.8 28.7 118.8 27.0 54.2 41.3 15.4 44.7 42.8 108.3 32.4 29.1 42.2 63.5 96.6 34.9 184.4 53.8 125.1 47.8 57.1 27.1 51.4 39.7 11.1 38.2 43.3 143.6 21.1 27.0 161.0 42.7 60.4 144.8 90.1 29.0 70.7 58.7 78.2 24.0 74.5 42.0 61.7 30.3 337.1 40.1 48.6 74.9 26.0 17.5 45.3 62.5 27.9 76.1 35.7 88.6 84.7 24.5 86.1 65.2 0.1 5.9 1.8 7.4 6.6 8.9 5.8 7.0 7.0 8.7 5.3 7.1 8.6 0.3 6.3 8.9 8.9 7.6 5.8 27.5 25.2 24.0 30.6 23.4 23.9 24.0 24.4 25.9 23.9 30.6 21.9 2.5 0.0 4.4 7.8 13.4 8.0 8.6 3.8 7.4 5.3 41.9 31.9 6.8 8.6 3.1 7.3 4.2 119.1 12.5 6.7 1.9 9.8 15.1 3.9 7.4 6.2 5.4 12.6 7.2 8.2 111.7 6.0 5.6 6.9 0.0 18.1 7.1 67.7 21.8 11.8 9.0 9.2 4.1 9.1 6.0 32.0 7.2 6.6 0.0 29.0 47.9 2.5 6.2 6.6 5.0 7.0 4.3 13.9 10.0 14.1 11.7 3.9 2.9 3.1 13.1 5.5 5.2 35.1 21.5 7.6 6.3 227.9 8.6 9.4 15.2 7.8 SLC9A1 "APNH, NHE1, PPP1R143" ENSG00000090020 "Solute carrier family 9 member A1" P19634 1 27098809-27166981 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" Calmodulin-binding "Deafness, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 76.5;stomach 1: 65.9" "Cell type enhanced" "Detected in many" "Distal enterocytes: 81.5;Gastric mucus-secreting cells: 160.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022371, HPA048532, HPA052891" Enhanced Supported "Plasma membrane" NA NA 21000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "CAB022371: , HPA048532: AB_2680431, HPA052891: AB_2681981" "unprognostic (6.18e-2)" "unprognostic (1.59e-1)" "unprognostic (2.21e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (7.47e-4)" "unprognostic (2.70e-2)" "unprognostic (4.33e-3)" "unprognostic (3.18e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (7.10e-4)" "unprognostic (3.44e-2)" "unprognostic (6.95e-2)" "unprognostic (2.05e-2)" "unprognostic (1.27e-2)" "unprognostic (1.60e-1)" "unprognostic (3.34e-1)" "unprognostic (1.16e-2)" 9.6 10.7 6.1 10.4 14.7 11.5 9.0 2.8 10.8 10.9 0.2 18.6 29.3 10.9 8.0 11.0 7.6 16.9 13.7 2.3 5.3 5.8 2.4 13.2 7.0 13.8 4.7 7.0 8.6 20.7 8.2 21.9 11.2 9.0 13.6 4.5 76.5 19.4 4.6 10.5 19.0 10.7 0.5 11.6 65.9 10.1 10.4 6.3 9.5 4.9 6.7 15.1 9.2 2.4 32.3 10.7 9.9 10.1 21.8 15.7 60.8 25.9 38.5 21.7 23.5 13.0 20.0 14.4 21.9 33.4 10.5 38.9 9.8 62.4 13.4 17.4 9.4 21.9 7.1 5.5 66.1 13.1 16.0 19.7 29.5 36.5 50.7 15.8 36.3 9.8 6.3 13.4 32.3 18.7 6.8 6.4 14.0 38.2 21.9 11.8 9.0 6.7 10.9 46.3 11.4 3.7 21.5 28.4 12.6 10.0 13.3 7.9 39.9 23.0 9.4 21.7 14.5 12.6 8.6 4.3 24.6 14.1 13.5 0.0 0.6 0.6 0.7 0.3 1.5 0.1 0.8 0.7 0.2 0.3 0.5 0.6 2.0 0.1 0.6 0.0 0.3 0.8 6.1 14.7 2.8 10.8 2.3 5.3 13.8 4.7 11.2 0.5 10.4 2.4 13.5 6.4 14.8 6.5 7.9 31.2 17.9 14.6 13.1 7.4 21.7 23.2 13.5 7.2 8.3 11.0 0.0 40.3 11.9 81.5 0.0 9.1 26.5 13.8 15.9 9.7 12.5 0.4 14.1 12.5 19.4 12.7 160.0 26.5 27.3 7.5 6.8 1.2 12.9 20.2 14.1 15.0 4.1 5.7 5.1 14.4 9.3 12.7 7.2 8.4 4.3 8.2 12.3 4.0 4.6 28.1 43.1 13.2 4.8 9.6 38.9 1.2 5.9 3.8 6.6 20.8 9.8 3.6 4.4 15.0 25.1 52.9 9.8 4.8 18.3 18.3 SLC9A3 NHE3 ENSG00000066230 "Solute carrier family 9 member A3" P48764 5 470456-524449 "Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 45.4;intestine: 94.3;kidney: 62.5;stomach 1: 50.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 16.0;Collecting duct cells: 16.5;Proximal tubular cells: 40.7" "Cancer enhanced" "Detected in many" "stomach cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HDLM-2: 37.8" "Region enriched" "Detected in single" 14 "cerebellum: 4.1" "Low region specificity" "Detected in many" "HPA036493, HPA036669" Enhanced Supported "Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "HPA036493: AB_10673353, HPA036669: AB_10670843" "unprognostic (1.27e-1)" "unprognostic (4.88e-1)" "unprognostic (9.35e-3)" "unprognostic (1.11e-1)" "unprognostic (2.37e-1)" "unprognostic (3.35e-1)" "unprognostic (2.51e-1)" "unprognostic (9.40e-2)" "prognostic unfavorable (8.49e-4)" "unprognostic (5.18e-2)" "unprognostic (1.29e-1)" "unprognostic (3.69e-2)" "unprognostic (3.84e-1)" "unprognostic (1.30e-1)" "unprognostic (1.04e-1)" "unprognostic (1.24e-2)" "unprognostic (1.32e-1)" 2.9 4.4 3.0 10.4 2.5 1.9 3.1 6.1 5.0 3.8 1.7 94.3 46.0 2.9 4.0 8.7 4.9 45.4 3.2 4.7 2.5 62.5 2.4 2.8 3.8 3.8 2.3 4.3 6.7 6.2 0.7 2.1 3.7 7.3 10.8 1.7 9.9 3.8 6.2 19.0 68.1 3.3 1.3 3.7 50.1 5.8 3.4 3.5 4.9 3.9 3.4 2.5 2.5 2.6 6.7 5.1 10.4 10.5 2.5 3.0 7.8 5.3 3.9 8.0 5.0 11.0 7.4 14.0 7.5 3.0 5.5 10.0 6.1 4.0 3.9 37.8 10.7 6.7 23.4 5.4 3.9 5.5 8.2 4.2 8.1 3.5 5.4 3.9 2.4 6.3 9.6 7.5 2.9 9.0 6.0 24.3 4.0 17.8 8.3 8.6 9.3 8.3 2.8 4.8 11.5 5.0 19.0 5.3 4.2 4.5 12.3 4.2 2.9 8.0 7.2 5.3 3.9 12.4 5.8 8.5 5.2 21.2 5.6 0.0 0.7 0.1 2.6 0.3 2.2 0.9 3.3 2.4 0.9 1.0 3.9 3.1 0.1 2.4 0.2 1.2 2.7 1.8 3.0 2.5 6.1 5.0 4.7 2.5 3.8 2.3 3.7 1.3 3.4 2.6 3.8 16.0 5.8 0.0 1.5 0.0 0.0 0.0 0.0 0.0 7.3 8.9 0.7 0.0 5.6 16.5 0.0 0.0 3.4 0.7 5.9 9.0 0.0 3.8 3.6 2.3 0.0 0.0 0.3 8.8 0.0 2.2 0.0 2.6 2.5 5.3 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 4.6 0.0 0.0 0.0 0.1 7.7 0.0 0.0 0.7 0.0 1.1 40.7 2.9 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 2.3 5.4 0.0 0.0 SLC9A3R2 "E3KARP, NHERF-2, SIP-1, TKA-1" ENSG00000065054 "SLC9A3 regulator 2" Q15599 16 2025356-2039026 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 568.2" "Cell type enhanced" "Detected in many" "Adipocytes: 1013.8;Endothelial cells: 398.9;Hepatic stellate cells: 374.4;Hepatocytes: 227.4;Pancreatic endocrine cells: 326.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.2;intermediate monocyte: 1.6;myeloid DC: 3.9;plasmacytoid DC: 2.9" "Group enriched" "Detected in many" 5 "dendritic cells: 3.9;monocytes: 2.2" "Cell line enhanced" "Detected in many" "A549: 188.6;MCF7: 306.8;PC-3: 281.2;SK-BR-3: 188.3;U-251 MG: 193.6;WM-115: 202.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001672, HPA066520" Enhanced Supported "Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "HPA001672: AB_1080017, HPA066520: AB_2732748" "unprognostic (6.99e-2)" "unprognostic (4.56e-2)" "unprognostic (2.06e-2)" "prognostic favorable (1.03e-4)" "unprognostic (1.41e-2)" "unprognostic (1.54e-1)" "unprognostic (2.94e-3)" "unprognostic (9.17e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-2)" "unprognostic (2.17e-2)" "unprognostic (1.70e-2)" "unprognostic (2.20e-2)" "unprognostic (6.20e-3)" "unprognostic (9.10e-2)" "unprognostic (2.40e-1)" "unprognostic (2.80e-2)" 234.7 81.7 107.0 20.7 98.6 0.7 181.7 83.4 119.7 92.6 60.6 77.4 27.2 92.7 10.7 47.3 77.7 34.8 568.2 82.4 88.5 207.5 408.3 289.1 22.0 96.4 95.5 57.9 47.7 24.0 95.6 51.3 99.3 129.1 11.9 3.0 149.1 42.4 144.6 45.3 81.2 18.8 87.0 143.8 109.5 36.3 116.2 7.9 188.4 109.0 7.4 77.4 72.6 94.7 32.5 188.6 5.0 38.6 6.2 8.6 5.7 138.1 81.9 67.9 22.5 25.4 41.9 0.1 63.4 59.2 9.1 30.9 15.0 13.7 7.1 0.4 45.0 3.1 80.8 61.6 44.3 0.5 13.9 9.2 13.7 20.2 5.9 32.1 68.2 15.0 24.0 2.9 4.8 306.8 0.6 35.7 7.5 76.8 281.2 27.6 8.1 50.5 16.0 2.9 35.3 33.1 9.7 188.3 12.8 5.0 152.6 16.8 176.4 21.5 30.7 1.9 193.6 5.1 4.6 0.7 2.5 3.6 202.4 0.0 2.2 0.0 0.5 1.6 0.2 0.0 0.1 0.1 3.9 0.0 0.4 0.5 0.0 0.0 0.5 2.9 0.1 0.7 107.0 98.6 83.4 119.7 82.4 88.5 96.4 95.5 99.3 87.0 116.2 94.7 1013.8 3.2 10.5 4.2 7.3 15.2 19.6 17.1 7.4 2.6 79.5 65.0 25.5 88.6 47.3 12.9 0.0 1.0 11.4 13.3 5.9 36.1 16.1 37.2 36.8 398.9 21.5 17.3 3.4 8.8 0.8 53.5 33.6 67.8 0.0 5.1 374.4 227.4 2.6 3.3 5.5 77.0 22.4 30.9 35.1 35.8 82.0 7.0 33.8 31.9 2.2 17.2 7.2 4.0 3.6 326.8 9.3 44.4 4.9 51.8 1.2 14.7 27.3 5.0 26.3 22.3 69.1 7.0 15.4 3.4 11.4 1.0 8.8 9.5 18.0 66.6 SLCO1A2 "OATP, OATP-A, OATP1A2, SLC21A3" ENSG00000084453 "Solute carrier organic anion transporter family member 1A2" P46721 12 21264600-21419594 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 82.0;choroid plexus: 28.6" "Cell type enriched" "Detected in some" 4 "Oligodendrocytes: 487.6" "Cancer enhanced" "Detected in some" "testis cancer: 2.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "NTERA-2: 16.7;RPMI-8226: 12.0;SuSa: 16.1;U-266/70: 23.1;U-266/84: 9.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071152 Supported "Plasma membrane" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 70: Brain - Nervous system development" "Cluster 5: NTERA-2 - Transcription" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "HPA071152: AB_2686350" "unprognostic (5.43e-3)" "unprognostic (2.33e-1)" "unprognostic (1.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.08e-1)" "unprognostic (6.36e-2)" "unprognostic (7.63e-2)" "unprognostic (1.53e-1)" "unprognostic (3.82e-2)" "unprognostic (1.54e-2)" "unprognostic (1.51e-1)" "unprognostic (8.82e-2)" "unprognostic (1.66e-4)" "unprognostic (2.52e-2)" "unprognostic (3.20e-1)" "unprognostic (1.24e-1)" 0.0 0.1 48.9 0.1 65.9 0.1 4.0 43.5 80.2 0.0 28.6 0.1 0.0 0.1 0.2 0.1 0.3 0.2 0.9 41.3 46.4 1.2 11.5 2.8 0.7 54.0 51.9 0.2 2.4 0.2 0.4 1.2 52.6 0.7 0.0 0.6 15.8 0.0 0.4 0.5 0.1 0.0 45.2 0.5 0.3 1.9 48.3 0.6 0.2 0.0 0.4 0.2 0.0 82.0 2.1 0.6 0.8 0.1 0.0 0.0 3.4 0.0 0.0 0.1 0.0 3.8 1.4 0.1 2.1 0.2 0.0 0.3 0.3 0.2 0.5 0.7 0.9 0.0 0.5 1.5 0.0 0.4 0.3 0.0 1.7 0.2 0.2 1.5 0.1 0.4 4.0 1.2 0.0 2.6 0.4 0.1 16.7 2.0 0.2 0.2 0.2 12.0 0.0 2.2 1.9 2.9 0.0 0.2 0.2 16.1 3.2 0.9 0.0 0.1 1.7 0.8 0.4 23.1 9.8 0.2 0.1 0.3 0.0 0.2 0.1 0.1 0.4 0.1 0.6 0.4 0.6 0.4 0.0 0.2 0.6 0.4 1.3 0.3 0.0 0.2 0.5 0.1 48.9 65.9 43.5 80.2 41.3 46.4 54.0 51.9 52.6 45.2 48.3 82.0 0.0 35.3 3.1 5.9 0.0 0.0 0.0 0.0 0.0 0.2 3.5 2.8 0.5 0.0 0.0 1.8 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 2.8 0.0 0.0 0.7 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 1.5 0.1 0.0 0.8 0.0 0.0 0.0 0.0 4.5 0.0 0.1 0.0 102.1 0.0 0.1 0.0 2.5 487.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.1 0.4 1.5 0.0 0.0 0.1 0.1 0.0 0.0 0.0 SLCO1B1 "LST-1, OATP-C, OATP1B1, SLC21A6" ENSG00000134538 "Solute carrier organic anion transporter family member 1B1" Q9Y6L6 12 21131194-21239796 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 614 "liver: 537.2" "Cell type enriched" "Detected in some" 9 "Hepatocytes: 83.1" "Cancer enriched" "Detected in some" 96 "liver cancer: 52.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 1.1;NTERA-2: 1.3;RPMI-8226: 1.8;SuSa: 2.2" "HPA050892, HPA073093" Supported Supported "Plasma membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA050892: AB_2681265, HPA073093: " "unprognostic (5.45e-1)" "unprognostic (1.82e-4)" "unprognostic (2.43e-3)" "unprognostic (1.96e-3)" "unprognostic (1.80e-1)" "unprognostic (2.41e-1)" "unprognostic (8.82e-2)" "unprognostic (5.63e-2)" "unprognostic (3.86e-2)" "unprognostic (3.49e-1)" 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.1 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 537.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.3 0.0 0.1 0.0 0.2 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.2 0.1 0.2 0.1 0.2 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 83.1 0.0 0.0 0.2 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 SLCO1B3 "OATP1B3, OATP8, SLC21A8" ENSG00000111700 "Solute carrier organic anion transporter family member 1B3" Q9NPD5 12 20810702-20916911 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "liver: 265.1" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 203.4" "Cancer enriched" "Detected in many" 4 "liver cancer: 5.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 65.3;A549: 17.5;CAPAN-2: 12.6;GAMG: 13.6;HeLa: 14.2;PC-3: 17.3;U-2 OS: 14.7" "HPA004943, HPA050892" Enhanced Supported "Plasma membrane" NA NA "Cluster 62: Liver - Hemostasis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" "HPA004943: AB_1854758, HPA050892: AB_2681265" "unprognostic (5.36e-2)" "unprognostic (1.25e-1)" "unprognostic (6.95e-2)" "unprognostic (1.63e-2)" "unprognostic (1.89e-2)" "unprognostic (7.09e-2)" "unprognostic (3.08e-2)" "unprognostic (1.54e-2)" "unprognostic (7.37e-2)" "unprognostic (1.50e-1)" "unprognostic (6.61e-3)" "unprognostic (2.36e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 13.0 16.2 0.3 0.2 0.1 0.4 0.3 0.0 0.3 0.0 0.5 0.0 0.0 265.1 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 65.3 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 12.6 0.0 4.3 0.0 13.6 0.1 0.0 0.5 0.0 0.0 0.0 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 2.9 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 14.7 0.0 1.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 1.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 203.4 0.0 0.0 0.5 0.0 0.0 1.6 0.0 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.2 0.2 SLIT1 "MEGF4, SLIL1, Slit-1, SLIT3" ENSG00000187122 "Slit guidance ligand 1" O75093 10 96998038-97185959 "Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 32.5;pituitary gland: 13.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.0;Excitatory neurons: 96.2;Inhibitory neurons: 34.6;Late spermatids: 25.5;Oligodendrocyte precursor cells: 25.1" "Group enriched" "Detected in many" 4 "glioma: 9.2;thyroid cancer: 10.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "JURKAT: 23.2;MOLT-4: 81.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA006879 Approved "Plasma membrane" "Secreted in brain" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA006879: AB_1078197" "unprognostic (2.72e-1)" "unprognostic (2.25e-2)" "unprognostic (5.67e-3)" "unprognostic (1.43e-5)" "unprognostic (8.40e-2)" "unprognostic (2.60e-3)" "unprognostic (4.57e-2)" "unprognostic (1.81e-2)" "unprognostic (3.53e-1)" "unprognostic (6.06e-2)" "unprognostic (2.28e-3)" "unprognostic (1.46e-1)" "unprognostic (1.08e-5)" "unprognostic (1.66e-1)" "unprognostic (2.18e-1)" "unprognostic (1.21e-1)" "unprognostic (4.39e-3)" 0.4 0.1 28.6 0.2 32.5 0.2 0.1 0.0 29.8 0.1 0.0 0.5 0.1 0.1 0.0 0.0 0.2 0.0 0.1 28.7 5.2 0.1 0.1 0.2 0.1 0.0 2.1 0.1 0.6 0.1 13.5 0.0 0.0 0.3 0.1 0.8 0.1 0.0 0.1 0.0 0.2 0.1 1.6 0.3 0.3 1.8 14.1 2.4 2.5 0.0 0.1 0.1 0.1 7.4 0.0 0.1 3.7 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.1 0.3 0.0 0.0 0.1 3.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 23.2 0.0 0.6 0.0 0.2 81.0 0.3 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 4.9 2.1 0.0 0.0 0.8 0.1 0.0 0.3 0.0 0.0 0.2 0.0 0.1 1.7 0.0 0.1 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 28.6 32.5 0.0 29.8 28.7 5.2 0.0 2.1 0.0 1.6 14.1 7.4 0.2 0.0 0.0 6.5 0.5 0.0 0.1 0.0 0.0 3.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 27.0 0.5 0.1 0.1 1.8 0.0 96.2 0.0 0.0 0.2 0.0 1.1 0.0 0.2 0.0 0.0 0.5 0.0 34.6 0.0 0.0 0.3 0.0 25.5 0.0 0.3 0.0 2.8 0.2 0.1 0.0 25.1 3.1 0.0 0.0 0.4 0.0 0.1 0.0 0.0 1.5 0.2 0.0 0.1 0.2 3.4 2.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 SLITRK6 FLJ22774 ENSG00000184564 "SLIT and NTRK like family member 6" Q9H5Y7 13 85792790-85806683 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Hearing, Sensory transduction, Vision" Deafness "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 27.7;urinary bladder: 14.7" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 22.8;Bipolar cells: 41.7;Club cells: 27.4;Ionocytes: 16.2;Respiratory ciliated cells: 41.6" "Cancer enhanced" "Detected in many" "breast cancer: 21.1;urothelial cancer: 18.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "hTCEpi: 28.8;OE19: 24.2;RT4: 101.4;WM-115: 23.7" "Region enhanced" "Detected in many" "thalamus: 22.6" "Low region specificity" "Detected in many" "HPA014491, HPA014513" Uncertain Supported "Plasma membrane" NA NA 28000 "Cluster 24: Salivary gland - Salivary secretion" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "HPA014491: AB_10601603, HPA014513: AB_2669026" "unprognostic (6.14e-2)" "unprognostic (5.21e-3)" "unprognostic (1.40e-1)" "unprognostic (2.66e-2)" "unprognostic (2.46e-2)" "prognostic unfavorable (8.52e-4)" "unprognostic (6.10e-2)" "unprognostic (1.72e-2)" "unprognostic (1.69e-1)" "unprognostic (4.82e-2)" "unprognostic (7.60e-2)" "unprognostic (7.92e-2)" "unprognostic (3.31e-5)" "unprognostic (5.60e-2)" "unprognostic (1.81e-1)" "unprognostic (1.83e-1)" "unprognostic (2.51e-2)" 0.1 0.2 1.0 0.9 4.4 0.0 3.2 2.2 1.9 1.2 0.1 5.5 3.5 1.0 2.5 1.9 0.5 1.4 1.5 0.2 2.0 0.1 0.9 3.3 0.0 0.6 2.3 0.0 0.2 0.0 0.1 0.9 0.9 7.6 6.8 4.8 27.7 2.2 0.0 5.6 5.7 0.4 0.3 0.1 1.5 0.3 5.7 0.2 0.3 0.1 0.1 14.7 1.4 0.4 0.0 2.9 0.1 0.5 0.0 0.0 0.0 2.8 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 4.9 0.0 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.0 28.8 0.0 3.3 2.7 0.0 0.0 0.0 0.1 0.0 3.3 0.0 0.0 0.0 24.2 1.9 0.2 0.0 0.0 0.0 101.4 1.0 1.2 0.5 0.1 0.1 1.7 0.5 0.0 0.0 0.3 1.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 23.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 4.4 2.2 1.9 0.2 2.0 0.6 2.3 0.9 0.3 5.7 0.4 0.1 0.0 1.8 0.0 0.0 3.8 5.0 22.8 0.0 41.7 5.3 1.5 0.4 0.0 27.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 1.2 4.3 0.3 0.0 0.0 0.1 0.0 0.0 2.0 0.0 2.7 0.0 2.2 2.2 0.0 0.2 0.0 0.4 1.7 16.2 0.0 0.6 0.0 9.6 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 1.8 0.0 0.4 0.0 1.5 0.0 0.1 41.6 2.0 0.0 0.0 0.8 0.0 0.1 3.8 2.4 0.0 0.2 0.1 0.5 4.5 SMOC1 ENSG00000198732 "SPARC related modular calcium binding 1" Q9H4F8 14 69854131-70032366 "Disease related genes, Human disease related genes, Predicted secreted proteins" Differentiation "Developmental protein" "Disease variant, Microphthalmia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.2;liver: 67.9" "Cell type enhanced" "Detected in many" "Hepatocytes: 104.4;Oligodendrocyte precursor cells: 372.4;Oligodendrocytes: 81.1;Peritubular cells: 133.2" "Cancer enhanced" "Detected in many" "glioma: 27.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 11 "plasmacytoid DC: 1.3" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.3" "Cell line enhanced" "Detected in some" "AF22: 50.3;HeLa: 122.6;HSkMC: 38.3;SiHa: 72.1;SK-BR-3: 30.6;U-266/70: 42.3;U-87 MG: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004153, CAB034427" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 140000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 15: Liver - Metabolism" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "CAB034427: AB_2193382, HPA004153: AB_1080035" "unprognostic (3.31e-1)" "unprognostic (2.17e-3)" "unprognostic (8.17e-2)" "unprognostic (1.96e-2)" "unprognostic (1.89e-2)" "unprognostic (4.04e-1)" "unprognostic (6.75e-3)" "unprognostic (2.09e-3)" "unprognostic (4.76e-2)" "unprognostic (2.80e-2)" "unprognostic (5.10e-2)" "unprognostic (5.63e-2)" "unprognostic (4.09e-2)" "unprognostic (3.92e-1)" "unprognostic (2.57e-1)" "unprognostic (1.34e-1)" "unprognostic (1.87e-1)" 15.9 10.3 29.2 0.5 30.3 0.1 6.2 53.2 29.1 9.4 17.5 1.3 1.9 2.2 7.7 0.3 6.6 0.5 8.3 27.9 31.6 3.0 67.9 0.6 0.9 38.4 38.8 1.4 10.3 0.3 4.4 8.0 36.8 33.4 1.0 2.4 5.8 38.8 12.7 2.4 1.4 1.0 41.2 27.2 3.8 35.7 29.6 0.4 4.2 2.7 0.5 1.3 6.3 52.8 0.0 3.3 50.3 0.0 9.8 6.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.2 0.0 2.9 0.0 0.0 20.4 0.0 122.6 17.4 0.1 0.0 0.0 38.3 11.9 1.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.2 0.3 0.0 0.0 0.0 1.6 0.0 0.0 0.0 2.0 0.2 72.1 30.6 0.0 0.3 0.0 0.0 0.4 0.3 2.9 0.0 0.0 42.3 0.0 0.0 51.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 29.2 30.3 53.2 29.1 27.9 31.6 38.4 38.8 36.8 41.2 29.6 52.8 0.3 0.0 0.0 12.1 2.5 0.3 0.0 0.7 0.0 2.1 1.3 3.8 2.0 7.2 0.1 0.0 16.7 24.2 4.0 0.0 0.0 0.3 4.7 11.9 0.6 2.9 15.6 0.0 1.0 2.3 0.8 6.0 3.6 1.5 0.0 1.4 3.3 104.4 2.8 0.0 13.5 0.1 14.2 2.5 0.4 19.0 7.8 0.3 0.0 1.0 0.1 0.3 0.0 372.4 81.1 3.7 0.1 133.2 12.4 0.0 0.0 0.0 1.1 0.3 0.0 0.7 2.3 2.1 3.9 0.0 0.4 40.2 0.4 0.4 0.0 0.1 SMPX "Chisel, Csl, DFN6, DFNX4" ENSG00000091482 "Small muscle protein X-linked" Q9UHP9 X 21705978-21758116 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 39 "heart muscle: 757.5;skeletal muscle: 1183.4;tongue: 1097.5" "Cell type enriched" "Detected in some" 22 "Cardiomyocytes: 807.6" "Group enriched" "Detected in many" 4 "head and neck cancer: 7.2;stomach cancer: 1.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "GAMG: 23.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA077360 Approved "Plasma membrane" NA NA 62000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" "HPA077360: AB_2732342" "unprognostic (7.29e-2)" "unprognostic (1.78e-1)" "unprognostic (2.63e-1)" "unprognostic (1.28e-1)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.39e-2)" "unprognostic (7.46e-2)" "unprognostic (5.27e-1)" "unprognostic (1.96e-2)" "unprognostic (3.97e-2)" "unprognostic (3.58e-2)" "unprognostic (2.67e-2)" "unprognostic (2.82e-1)" "unprognostic (8.38e-2)" 0.2 0.1 2.6 0.5 2.4 0.1 1.1 3.6 3.8 0.3 0.9 25.6 0.7 0.4 0.0 20.0 0.7 0.5 757.5 1.6 4.1 0.1 1.2 0.5 0.2 1.7 3.3 1.1 0.2 0.0 0.2 0.0 1.5 11.1 3.4 1.7 17.8 0.7 1183.4 0.5 4.1 12.6 1.3 0.1 7.2 0.2 5.3 1.5 0.2 1097.5 0.1 3.2 0.2 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.2 0.0 0.0 0.0 0.3 3.4 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.6 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.4 3.6 3.8 1.6 4.1 1.7 3.3 1.5 1.3 5.3 2.2 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 807.6 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.6 0.0 0.0 16.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 35.6 9.5 0.1 0.3 0.0 0.0 0.3 0.1 2.1 0.1 0.0 SNAP23 "HsT17016, SNAP23A, SNAP23B" ENSG00000092531 "Synaptosome associated protein 23" O00161 15 42491233-42545356 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 326.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 675.6" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001214, CAB037083, CAB037317" Approved Supported "Plasma membrane" NA NA 3900000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "CAB037083: AB_477494, CAB037317: AB_261925, HPA001214: AB_1080037" "unprognostic (1.77e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" "unprognostic (3.76e-3)" "unprognostic (2.42e-2)" "unprognostic (1.65e-1)" "unprognostic (9.67e-3)" "unprognostic (1.60e-1)" "unprognostic (2.60e-1)" "unprognostic (2.93e-1)" "unprognostic (7.31e-2)" "unprognostic (1.36e-1)" "unprognostic (2.04e-2)" "unprognostic (1.59e-1)" "unprognostic (8.95e-2)" "unprognostic (1.10e-1)" "unprognostic (3.93e-2)" 44.4 30.3 23.0 62.9 27.7 35.1 38.2 25.7 46.3 37.5 28.6 52.8 50.3 43.2 35.3 31.9 29.8 40.2 44.6 23.5 24.8 42.4 44.4 45.2 84.6 28.0 25.9 34.6 24.2 36.2 12.9 68.9 31.3 49.2 51.2 12.8 45.2 30.9 43.9 26.5 56.4 48.3 25.6 70.3 39.9 36.1 27.5 38.0 33.1 28.7 78.7 42.5 23.9 37.2 58.3 29.7 55.7 54.7 91.8 70.4 85.1 77.6 61.8 50.8 59.1 93.0 27.8 35.1 91.3 52.3 48.1 52.7 63.2 50.1 70.9 58.4 35.3 149.2 30.5 89.1 66.8 57.4 136.6 59.1 37.9 43.5 70.4 64.7 192.9 69.4 121.6 31.4 67.1 24.1 68.3 69.4 46.0 94.3 22.8 122.4 33.8 55.1 71.8 57.8 9.0 36.3 57.2 51.3 56.4 83.5 76.2 91.6 155.0 46.6 61.2 52.1 80.4 59.1 122.3 153.2 56.3 120.0 62.8 244.8 159.8 675.6 51.4 237.6 60.2 110.2 53.5 50.2 148.2 103.9 68.0 52.4 361.9 70.7 236.0 62.6 66.4 179.4 23.0 27.7 25.7 46.3 23.5 24.8 28.0 25.9 31.3 25.6 27.5 37.2 58.9 112.2 30.5 30.7 79.0 50.7 107.6 30.8 34.7 7.7 41.9 19.8 19.2 38.6 32.8 20.2 20.9 75.9 45.3 61.3 56.7 71.1 207.6 34.4 38.6 77.1 14.9 25.0 21.2 52.2 109.5 44.3 32.6 41.2 83.5 22.4 77.4 28.0 88.9 5.0 23.6 80.2 52.9 125.4 112.8 326.0 39.1 131.8 44.4 36.5 120.0 14.6 53.5 39.7 54.6 110.8 52.8 60.5 27.9 79.9 55.0 76.2 42.6 18.4 52.6 42.1 40.6 16.7 7.9 29.3 38.5 142.6 48.2 47.8 39.7 64.7 SPN "CD43, GPL115, LSN" ENSG00000197471 Sialophorin P16150 16 29662979-29670876 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "bone marrow: 71.8;lung: 28.3;lymphoid tissue: 51.1" "Cell type enhanced" "Detected in many" "dendritic cells: 131.6;Erythroid cells: 125.9;Macrophages: 65.8;monocytes: 66.4;NK-cells: 352.2;Plasma cells: 60.3;T-cells: 94.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 218.0" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 278.8;HL-60: 281.5;HMC-1: 158.3;MOLT-4: 122.2;REH: 98.4;THP-1: 164.1;U-937: 205.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB002666, HPA055244" Enhanced Approved "Plasma membrane" NA NA 270000 "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "CAB002666: , HPA055244: AB_2682756" "prognostic favorable (1.40e-4)" "unprognostic (1.63e-3)" "unprognostic (3.14e-2)" "prognostic favorable (3.08e-5)" "unprognostic (2.68e-2)" "unprognostic (2.49e-3)" "unprognostic (4.02e-2)" "unprognostic (4.17e-2)" "prognostic favorable (1.88e-4)" "unprognostic (1.70e-1)" "unprognostic (4.67e-2)" "unprognostic (2.68e-1)" "unprognostic (2.61e-2)" "unprognostic (4.52e-2)" "unprognostic (4.14e-2)" "unprognostic (5.85e-2)" "unprognostic (4.72e-2)" 4.0 0.6 0.8 14.4 1.0 71.8 1.8 1.1 0.9 1.4 0.2 3.9 5.5 1.6 1.1 3.0 2.0 4.3 2.8 0.9 1.4 0.8 2.6 28.3 26.3 3.5 1.3 0.6 1.0 0.6 0.2 0.9 2.5 1.3 5.3 0.3 2.3 1.1 0.8 2.8 6.3 2.3 1.8 19.0 5.0 0.4 2.5 51.1 0.8 0.3 23.0 4.2 0.5 4.1 0.2 0.2 0.1 0.3 0.1 0.0 0.9 0.0 0.1 0.0 0.0 0.9 0.1 0.6 1.4 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.1 278.8 0.2 2.0 0.0 281.5 158.3 0.0 0.0 0.1 0.0 0.1 0.0 68.0 96.1 76.9 0.5 0.2 122.2 70.1 0.1 0.0 0.0 98.4 1.1 2.2 0.0 0.0 0.2 0.1 0.2 0.3 0.1 0.3 0.1 164.1 0.4 0.0 0.2 0.2 0.2 0.3 5.8 40.7 0.3 205.4 0.3 13.6 23.2 14.6 96.3 96.3 51.4 3.7 38.5 65.5 34.0 1.1 26.3 47.6 3.6 69.4 218.0 27.2 34.7 52.1 0.8 1.0 1.1 0.9 0.9 1.4 3.5 1.3 2.5 1.8 2.5 4.1 1.2 9.6 16.9 0.0 10.8 2.2 0.9 0.0 0.0 0.6 1.0 0.8 5.3 1.5 2.5 1.8 0.0 0.2 131.6 0.1 0.0 0.1 0.1 0.5 0.6 3.0 0.0 125.9 0.0 0.0 0.4 3.0 5.1 0.7 43.7 0.8 4.6 1.5 27.0 1.7 0.0 0.3 0.0 28.8 30.3 0.0 0.0 65.8 1.8 1.9 66.4 0.5 352.2 1.5 0.0 0.0 0.1 0.0 60.3 0.5 0.1 0.6 1.5 1.9 0.0 0.8 1.0 0.2 0.6 0.1 2.0 0.3 94.8 0.1 0.2 0.6 SRPRB "APMCF1, SR-beta" ENSG00000144867 "SRP receptor subunit beta" Q9Y5M8 3 133784023-133825772 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011173 Approved Approved "Plasma membrane" NA NA 12000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 25: Pancreas - Digestion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" "HPA011173: AB_1857484" "unprognostic (5.44e-2)" "unprognostic (1.32e-1)" "unprognostic (6.40e-2)" "unprognostic (1.58e-2)" "unprognostic (2.61e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.99e-1)" "unprognostic (3.60e-2)" "unprognostic (6.07e-3)" "unprognostic (8.45e-2)" "unprognostic (1.31e-2)" "unprognostic (3.79e-2)" "unprognostic (5.08e-2)" "unprognostic (7.37e-2)" "unprognostic (6.47e-2)" "unprognostic (2.26e-2)" 20.4 26.8 21.1 18.4 23.3 14.1 24.7 23.2 24.6 26.6 26.4 23.1 19.0 14.4 47.9 29.9 17.9 13.3 16.9 21.1 23.7 26.6 52.9 14.8 15.3 24.5 24.4 13.8 83.2 27.6 25.4 16.0 24.5 18.2 26.1 6.8 49.9 23.7 19.0 15.4 15.4 21.0 22.4 15.5 24.4 26.8 23.1 10.7 26.1 16.5 28.9 23.7 13.8 28.9 44.8 37.5 22.6 72.7 91.8 62.3 45.6 97.4 49.4 50.2 44.3 73.7 34.6 90.4 131.5 72.4 51.2 64.8 69.8 50.9 47.7 57.8 59.6 80.6 34.9 65.2 110.8 124.5 56.7 57.3 83.3 46.2 135.9 28.1 43.5 43.6 68.1 96.9 55.5 65.6 40.9 55.5 43.8 120.3 63.8 49.1 43.5 190.8 61.9 32.1 74.7 32.7 77.3 66.6 28.3 17.0 76.9 55.1 46.0 51.9 29.0 82.8 54.0 118.8 131.5 131.4 45.3 82.9 56.9 13.1 30.5 3.9 54.3 41.1 73.0 38.9 45.4 47.9 36.3 36.7 43.3 51.9 2.2 41.5 27.5 53.8 29.1 50.3 21.1 23.3 23.2 24.6 21.1 23.7 24.5 24.4 24.5 22.4 23.1 28.9 16.8 16.0 20.6 15.3 43.4 37.7 32.0 38.2 11.4 6.5 36.4 22.0 26.6 37.1 32.8 36.8 12.5 65.4 29.1 14.2 11.7 46.0 68.9 18.7 51.2 26.3 32.2 21.7 16.0 67.4 71.2 40.6 28.5 30.1 32.4 19.8 18.9 88.4 49.4 6.7 15.7 58.8 36.7 19.7 23.1 35.9 32.0 20.6 35.6 8.4 16.4 17.2 20.6 17.6 92.6 36.0 17.7 27.8 146.0 52.3 20.0 33.0 24.3 9.4 13.1 38.2 30.2 60.1 40.6 52.1 31.5 51.7 26.1 52.9 43.9 28.5 SSTR5 ENSG00000162009 "Somatostatin receptor 5" P35346 16 1078781-1080142 "FDA approved drug targets, G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 6.9;kidney: 2.9;pituitary gland: 7.3" "Not detected" "Not detected" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in single" "hypothalamus: 1.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "Hep G2: 15.4;PC-3: 54.7" "Group enriched" "Detected in some" 5 "basal ganglia: 4.1;hypothalamus: 2.3" "Low region specificity" "Detected in many" HPA066503 Supported "Plasma membrane" NA NA "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane" "HPA066503: AB_2685679" "unprognostic (2.16e-2)" "unprognostic (7.31e-2)" "unprognostic (3.69e-2)" "unprognostic (2.39e-2)" "unprognostic (2.14e-1)" "unprognostic (9.89e-3)" "unprognostic (1.72e-2)" "unprognostic (1.72e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-1)" "unprognostic (4.09e-2)" 0.0 2.5 0.1 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 6.9 0.3 1.5 2.9 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.0 7.3 0.0 0.1 0.7 0.0 0.2 1.0 0.1 0.2 0.0 0.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.4 0.0 0.2 0.2 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 15.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 54.7 0.0 2.1 0.6 0.0 2.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.4 0.3 1.5 0.2 0.3 0.1 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 STAMBPL1 "ALMalpha, AMSH-FP, AMSH-LP, bA399O19.2, FLJ31524, KIAA1373" ENSG00000138134 "STAM binding protein like 1" Q96FJ0 10 88879734-88975153 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 23.8" "Cell type enhanced" "Detected in many" "Early spermatids: 54.3;Excitatory neurons: 60.5;Microglial cells: 32.8;Spermatocytes: 40.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040202 Uncertain Approved "Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 14: B-cells - Humoral immune response" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "HPA040202: AB_10805708" "unprognostic (2.73e-1)" "unprognostic (1.95e-1)" "unprognostic (7.56e-2)" "unprognostic (4.25e-2)" "unprognostic (6.46e-2)" "unprognostic (6.27e-2)" "unprognostic (1.68e-2)" "unprognostic (1.05e-2)" "unprognostic (4.67e-2)" "unprognostic (8.20e-2)" "unprognostic (2.78e-1)" "unprognostic (6.57e-2)" "prognostic unfavorable (1.08e-5)" "unprognostic (4.41e-2)" "unprognostic (4.06e-2)" "unprognostic (1.50e-1)" "unprognostic (4.40e-3)" 3.9 23.8 5.5 10.4 6.5 5.3 2.5 2.6 9.0 2.7 0.0 8.7 6.4 4.2 0.9 4.4 2.2 4.1 8.0 6.2 1.4 1.8 1.8 3.6 16.2 1.1 0.5 12.7 2.3 3.4 5.5 1.2 2.6 1.7 9.7 4.4 1.4 1.1 0.7 3.7 7.3 3.0 1.9 7.2 5.1 18.0 0.5 7.1 1.2 1.5 12.2 6.4 2.5 5.6 14.8 16.5 1.0 0.6 14.4 27.7 0.0 31.5 28.9 19.0 16.3 0.3 25.6 18.6 2.3 15.6 12.3 6.4 4.1 4.5 17.9 16.3 10.8 4.6 10.4 0.9 10.3 20.2 5.7 10.6 1.4 31.6 9.6 18.4 0.6 20.9 0.0 7.3 50.0 3.0 34.2 21.5 6.6 13.3 14.1 3.4 13.0 3.8 6.5 4.7 9.6 11.9 3.7 1.1 37.5 3.6 2.3 4.1 4.9 17.0 12.4 20.7 19.9 17.7 19.7 17.2 18.2 19.4 16.9 9.5 1.0 8.1 10.7 1.1 14.1 17.7 15.5 13.7 1.7 14.9 16.6 10.0 1.4 23.6 0.5 27.9 28.3 8.0 5.5 6.5 2.6 9.0 6.2 1.4 1.1 0.5 2.6 1.9 0.5 5.6 2.3 0.0 4.5 10.7 16.7 9.6 5.3 1.4 1.2 3.6 2.3 1.4 8.6 0.0 0.2 5.5 0.0 0.1 18.8 7.6 0.0 1.3 54.3 1.9 6.5 1.8 9.1 3.4 60.5 1.8 0.1 7.7 3.1 1.4 5.1 7.4 1.8 2.4 3.7 6.7 26.2 9.3 4.1 1.3 9.6 20.7 7.2 3.1 0.0 32.8 1.0 9.3 12.3 26.2 1.9 1.9 2.8 1.5 14.2 1.9 7.9 0.8 5.0 0.4 0.0 20.4 6.4 40.2 2.5 5.9 11.4 0.1 17.6 14.9 14.2 2.9 STARD4 ENSG00000164211 "StAR related lipid transfer domain containing 4" Q96DR4 5 111496033-111512590 "Metabolic proteins, Predicted intracellular proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046177, HPA048081" Approved Approved "Plasma membrane" NA Yes "Cluster 46: Basophils - DNA binding" "Cluster 9: Intestine - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 15: Hepatocytes - Hemostasis" "Plasma membrane" "HPA046177: AB_2679570, HPA048081: AB_2680253" "unprognostic (1.13e-1)" "unprognostic (7.07e-3)" "unprognostic (1.53e-2)" "unprognostic (1.64e-1)" "unprognostic (1.01e-1)" "unprognostic (1.21e-2)" "prognostic unfavorable (4.80e-5)" "unprognostic (1.31e-1)" "unprognostic (1.11e-1)" "unprognostic (4.26e-1)" "unprognostic (6.27e-2)" "unprognostic (1.39e-1)" "prognostic unfavorable (5.89e-5)" "unprognostic (2.00e-1)" "unprognostic (3.82e-3)" "unprognostic (4.01e-3)" "prognostic unfavorable (2.84e-4)" 6.2 15.8 8.3 15.9 15.8 19.4 3.9 25.2 12.6 10.2 11.5 14.7 40.8 7.7 16.2 8.5 5.0 9.7 15.0 9.5 10.6 8.5 34.1 20.9 12.6 16.0 16.7 6.5 6.1 14.4 8.2 27.3 13.8 20.7 16.9 12.0 6.6 9.9 1.5 2.5 35.7 6.9 10.1 12.1 17.9 6.8 14.8 7.2 9.0 1.7 10.1 7.7 9.2 11.3 20.6 10.0 48.2 29.4 42.4 84.0 16.3 21.0 46.6 29.8 89.1 37.7 59.9 24.5 8.4 13.4 89.0 9.1 24.8 71.8 28.8 23.7 10.4 19.1 33.3 22.8 46.4 9.5 11.7 44.6 48.3 64.1 47.6 35.6 56.6 23.5 10.7 46.5 20.8 3.9 23.7 17.3 16.6 0.6 5.5 5.4 53.3 22.5 44.6 6.7 27.2 105.6 0.0 12.3 19.0 32.1 16.0 30.4 84.4 25.6 22.9 17.2 8.9 15.9 15.8 21.6 24.3 34.8 13.2 7.1 1.4 0.9 2.5 2.1 1.3 1.7 1.2 1.9 1.8 1.7 1.2 1.9 0.0 2.1 1.5 1.3 0.8 1.4 8.3 15.8 25.2 12.6 9.5 10.6 16.0 16.7 13.8 10.1 14.8 11.3 8.2 25.6 34.8 16.0 13.1 1.0 1.4 35.0 1.2 10.8 1.6 0.4 17.8 8.6 18.1 9.2 8.4 15.6 24.8 37.3 1.9 7.8 9.4 6.7 3.5 20.2 21.4 3.6 38.8 9.2 6.0 6.0 15.8 11.5 32.3 6.5 5.0 39.9 20.3 6.7 20.8 32.5 22.4 19.6 26.7 8.3 7.2 27.8 3.6 20.6 5.7 7.1 9.2 20.1 23.6 10.0 30.0 7.9 17.6 3.3 30.1 5.7 9.5 7.6 19.7 2.4 15.2 8.7 9.4 6.8 2.6 14.1 14.5 38.2 23.0 5.2 STOML3 "Epb7.2l, SRO" ENSG00000133115 "Stomatin like 3" Q8TAV4 13 38965925-38990859 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "fallopian tube: 34.9" "Group enriched" "Detected in some" 19 "Endometrial ciliated cells: 75.5;Respiratory ciliated cells: 109.2" "Group enriched" "Detected in some" 4 "endometrial cancer: 2.4;lung cancer: 0.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 40 "AF22: 17.5" "Region enriched" "Detected in many" 6 "olfactory bulb: 23.6" "HPA012892, HPA071011" Enhanced Supported "Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 12: NES - Nervous system development" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" "HPA012892: AB_1857610, HPA071011: AB_2732169" "unprognostic (2.64e-1)" "unprognostic (1.91e-2)" "prognostic favorable (1.49e-4)" "unprognostic (1.82e-1)" "unprognostic (1.17e-1)" "unprognostic (4.24e-2)" "unprognostic (1.19e-1)" "unprognostic (2.14e-1)" "unprognostic (2.14e-1)" "unprognostic (1.07e-2)" "unprognostic (1.35e-2)" "unprognostic (3.07e-2)" "unprognostic (1.74e-1)" "unprognostic (1.22e-1)" 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.5 0.0 0.7 1.3 0.1 0.0 0.6 0.0 0.0 34.9 0.0 0.0 1.1 1.8 0.0 0.0 2.1 0.0 4.7 5.1 0.0 0.0 0.0 0.0 0.1 5.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 17.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.5 0.0 1.1 1.8 4.7 5.1 5.0 2.0 0.9 1.3 0.0 0.0 1.5 0.0 0.0 0.1 0.1 2.6 0.0 0.0 0.0 0.4 0.1 0.0 4.8 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.4 75.5 0.4 0.3 0.0 0.0 0.1 0.0 1.1 0.4 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 1.5 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 109.2 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.1 STX4 "p35-2, STX4A" ENSG00000103496 "Syntaxin 4" Q12846 16 31032889-31042975 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Neurotransmitter transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 149.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001330 Approved Enhanced "Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA001330: AB_1080167" "unprognostic (2.31e-3)" "prognostic favorable (3.65e-4)" "unprognostic (3.25e-2)" "unprognostic (4.76e-2)" "unprognostic (1.74e-2)" "unprognostic (1.63e-1)" "unprognostic (3.75e-3)" "unprognostic (5.64e-3)" "unprognostic (2.93e-2)" "unprognostic (1.01e-2)" "unprognostic (3.12e-1)" "unprognostic (1.16e-2)" "prognostic unfavorable (2.88e-9)" "unprognostic (6.90e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-1)" "unprognostic (3.26e-2)" 38.3 44.0 33.1 34.2 36.2 22.3 33.9 37.4 36.4 36.3 32.3 37.5 38.3 31.4 24.4 35.8 29.8 27.7 39.8 33.2 37.8 33.5 35.8 36.2 31.1 38.0 36.6 30.4 27.7 38.4 23.2 32.3 37.7 29.9 28.6 8.5 29.9 26.5 45.8 44.3 35.9 31.6 36.1 43.7 32.4 14.9 36.2 28.4 29.5 33.8 37.1 38.1 32.6 39.0 51.9 70.6 16.0 36.1 51.1 52.1 33.8 47.7 79.2 47.5 48.7 22.1 53.2 35.4 58.9 80.8 54.4 36.6 15.2 52.6 45.6 60.3 43.8 25.3 48.7 59.7 58.3 29.2 80.1 50.2 36.1 82.1 61.1 58.5 64.3 22.3 29.9 38.6 84.9 80.3 28.0 44.8 33.1 36.9 36.7 24.0 47.1 46.1 45.9 38.7 13.1 24.6 40.6 41.1 17.4 20.7 33.7 38.7 74.4 48.3 21.8 55.8 26.6 41.2 37.0 14.6 73.3 46.4 29.7 21.3 21.7 27.3 17.6 23.8 15.4 12.7 14.7 17.9 18.8 17.5 11.0 14.2 23.0 24.6 21.9 11.1 9.0 11.2 33.1 36.2 37.4 36.4 33.2 37.8 38.0 36.6 37.7 36.1 36.2 39.0 34.9 44.8 22.7 7.8 32.6 65.1 34.6 56.3 31.9 7.4 22.3 20.6 23.6 48.6 35.2 22.0 12.5 31.1 35.9 69.7 29.4 60.6 12.9 22.1 26.6 46.0 25.7 11.1 4.8 67.7 35.7 51.7 43.3 29.0 60.3 42.1 33.9 20.0 89.5 5.0 3.6 39.5 38.7 49.6 149.9 15.7 38.5 83.2 30.2 2.8 51.7 24.1 42.2 3.0 16.0 73.4 58.5 35.3 23.0 61.6 77.7 50.8 31.3 6.9 39.5 40.6 36.4 9.4 6.7 27.0 65.1 33.1 35.4 39.0 47.9 36.2 SUSD2 "BK65A6.2, FLJ22778, W5C5" ENSG00000099994 "Sushi domain containing 2" Q9UGT4 22 24181487-24189106 "Predicted membrane proteins" Receptor "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 99.8" "Group enriched" "Detected in many" 6 "Alveolar cells type 1: 250.0;Alveolar cells type 2: 151.5;Proximal enterocytes: 154.9" "Cancer enhanced" "Detected in all" "testis cancer: 64.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 29 "SK-BR-3: 898.7" "Low region specificity" "Detected in all" HPA004117 Enhanced Approved "Plasma membrane" NA NA 6800000 "Cluster 19: Lung - Lung function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "HPA004117: AB_1857674" "unprognostic (5.24e-3)" "unprognostic (1.60e-1)" "unprognostic (1.74e-1)" "unprognostic (7.30e-2)" "unprognostic (1.27e-2)" "unprognostic (5.40e-2)" "unprognostic (5.20e-2)" "unprognostic (1.89e-2)" "unprognostic (5.87e-2)" "unprognostic (1.20e-2)" "unprognostic (9.74e-3)" "unprognostic (8.97e-2)" "prognostic unfavorable (3.29e-5)" "unprognostic (2.72e-2)" "unprognostic (2.82e-2)" "unprognostic (1.88e-2)" "unprognostic (3.33e-3)" 12.1 9.6 4.9 1.9 2.8 0.2 9.5 1.7 5.8 13.6 2.2 4.8 12.8 9.8 0.5 2.8 15.0 1.8 12.5 1.6 5.3 32.6 2.9 99.8 2.2 22.9 6.9 5.4 4.3 1.5 7.1 3.6 26.5 5.6 1.0 0.1 4.7 5.6 2.2 28.2 34.6 3.4 6.8 3.6 6.3 3.2 13.2 0.8 17.8 1.4 1.3 5.4 11.0 10.0 5.1 10.4 0.1 0.0 18.8 24.3 0.8 2.4 0.1 0.1 0.0 7.8 0.6 1.4 21.5 0.5 0.4 1.4 0.1 0.5 0.0 0.6 0.3 0.0 0.4 30.6 8.0 0.0 0.3 21.5 0.4 0.1 6.2 0.0 0.1 0.0 0.5 0.3 0.0 9.1 0.3 0.4 0.7 2.5 0.3 0.3 0.0 2.5 0.1 0.2 1.7 13.5 0.7 898.7 0.2 3.6 3.0 0.0 0.0 0.1 0.9 0.7 0.1 1.1 1.0 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 2.8 1.7 5.8 1.6 5.3 22.9 6.9 26.5 6.8 13.2 10.0 1.7 250.0 151.5 0.3 0.6 0.3 0.3 2.6 0.0 0.0 3.4 3.4 6.8 0.0 20.9 1.8 0.0 13.8 0.3 0.7 5.9 0.1 0.0 1.3 0.7 1.1 1.8 0.0 0.2 0.0 0.7 6.7 0.5 1.3 3.8 0.1 2.9 0.5 1.1 0.0 0.1 5.5 2.0 0.0 0.3 0.4 0.6 0.8 0.0 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.4 154.9 27.8 3.6 0.0 0.0 0.6 22.1 1.7 1.3 0.7 2.7 26.4 1.1 0.0 1.6 0.6 SYNGR3 ENSG00000127561 "Synaptogyrin 3" O43761 16 1989660-1994275 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 10 "brain: 122.6" "Cell type enhanced" "Detected in many" "Excitatory neurons: 24.2;Inhibitory neurons: 33.7;Spermatogonia: 8.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Group enriched" "Detected in many" 5 "B-cells: 1.9;NK-cells: 2.0;T-cells: 1.1" "Cell line enhanced" "Detected in many" "HDLM-2: 49.9;HMC-1: 30.3;Karpas-707: 25.8;SK-BR-3: 32.1;U-266/70: 40.2" "CAB034278, HPA042842" Enhanced Approved "Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "CAB034278: AB_2200905, HPA042842: AB_2678198" "unprognostic (8.89e-3)" "prognostic favorable (6.92e-4)" "unprognostic (6.07e-3)" "unprognostic (2.94e-3)" "unprognostic (2.92e-2)" "unprognostic (8.06e-3)" "unprognostic (2.52e-1)" "unprognostic (5.70e-2)" "unprognostic (2.84e-2)" "unprognostic (1.06e-1)" "unprognostic (3.69e-3)" "unprognostic (1.05e-1)" "prognostic favorable (7.12e-7)" "unprognostic (1.03e-1)" "unprognostic (1.19e-1)" "unprognostic (2.79e-1)" "unprognostic (8.78e-2)" 0.3 9.4 83.0 2.9 86.4 0.9 0.3 35.7 106.5 0.5 10.6 5.3 1.3 0.2 0.0 0.5 0.4 0.4 0.9 74.7 110.7 3.8 0.3 1.0 3.2 88.2 95.3 0.6 0.8 7.3 12.3 1.6 122.6 0.8 1.1 9.5 1.1 0.1 0.1 0.6 5.9 0.7 34.3 2.5 2.3 5.6 121.3 0.5 0.4 0.0 3.7 0.4 1.3 70.5 0.9 4.0 3.7 0.5 0.4 0.4 4.5 1.9 3.1 1.5 1.2 6.3 2.9 6.2 1.4 1.4 4.1 3.5 4.1 0.5 0.4 49.9 2.9 0.1 5.9 3.1 2.1 0.0 30.3 0.9 0.2 0.1 1.0 7.2 0.4 1.9 17.9 25.8 0.7 4.7 0.3 0.3 19.0 0.7 1.8 0.0 0.5 4.9 2.4 0.1 8.6 10.7 4.4 32.1 0.4 2.0 4.5 0.4 0.7 0.9 14.5 0.1 0.7 40.2 5.0 7.2 0.6 5.5 0.6 0.0 0.3 0.0 0.3 0.1 0.8 1.2 0.6 1.1 0.3 1.9 0.7 0.3 0.0 2.0 0.3 0.0 0.6 0.4 83.0 86.4 35.7 106.5 74.7 110.7 88.2 95.3 122.6 34.3 121.3 70.5 0.1 0.0 0.6 3.3 5.0 0.3 0.8 0.6 1.2 5.0 0.2 0.3 5.4 0.0 0.6 0.0 2.1 0.5 2.1 0.9 1.9 2.0 0.8 0.0 0.1 0.5 0.0 0.0 24.2 0.5 0.8 1.2 0.5 0.1 1.3 1.4 0.0 0.0 0.3 6.7 33.7 0.5 0.0 0.6 0.4 0.5 0.0 0.5 0.0 1.9 2.7 1.1 2.1 2.5 3.5 1.2 0.0 0.0 2.3 5.5 0.1 0.1 0.9 2.1 0.0 0.1 0.3 3.0 8.6 0.4 0.3 3.1 2.9 0.4 0.3 1.7 TACR2 "NK2R, NKNAR, SKR, TAC2R" ENSG00000075073 "Tachykinin receptor 2" P21452 10 69403903-69416918 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "intestine: 184.0" "Cell type enhanced" "Detected in some" "Horizontal cells: 6.7;Kupffer cells: 2.4;Leydig cells: 2.8" "Cancer enriched" "Detected in many" 4 "stomach cancer: 6.7" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "SK-MEL-30: 4.2;U-87 MG: 2.3" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA076573 Approved "Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "HPA076573: AB_2732313" "unprognostic (2.83e-1)" "unprognostic (1.58e-3)" "unprognostic (2.48e-2)" "unprognostic (1.67e-1)" "unprognostic (4.22e-1)" "unprognostic (2.30e-1)" "unprognostic (1.30e-2)" "unprognostic (1.96e-2)" "unprognostic (3.72e-1)" "unprognostic (6.14e-2)" "unprognostic (2.45e-2)" "unprognostic (3.16e-2)" "unprognostic (9.88e-4)" "unprognostic (5.59e-3)" "unprognostic (4.31e-3)" "unprognostic (1.25e-3)" "unprognostic (1.32e-1)" 0.9 0.3 1.3 2.5 1.2 0.4 0.8 1.5 1.7 10.3 0.2 184.0 5.0 25.2 0.2 14.7 20.4 0.5 3.2 1.7 0.1 0.3 0.5 0.7 0.3 0.0 0.2 1.8 0.3 0.0 0.2 0.2 0.1 6.2 9.1 4.1 0.5 1.1 2.8 1.1 31.4 33.1 0.0 0.3 37.9 0.7 0.0 0.1 0.4 0.2 0.1 32.3 8.5 0.4 0.9 0.6 0.2 0.3 1.4 0.1 0.1 0.2 0.1 0.2 0.3 0.3 0.1 0.1 0.2 0.2 0.3 0.3 0.0 0.0 0.0 0.2 0.2 0.8 0.3 0.8 0.1 0.0 1.4 0.2 0.3 0.0 0.0 0.4 0.0 0.0 0.2 1.2 0.0 0.3 0.0 0.2 0.2 0.8 0.9 0.0 0.0 0.0 0.0 0.5 0.3 0.2 0.6 1.2 4.2 0.1 0.5 0.1 0.3 1.4 0.2 0.6 0.5 0.5 0.6 0.1 2.3 0.1 0.8 0.2 0.4 0.0 0.1 1.3 0.1 0.3 0.2 0.1 0.6 0.1 0.1 0.0 0.0 0.0 0.6 0.1 0.0 0.1 1.3 1.2 1.5 1.7 1.7 0.1 0.0 0.2 0.1 0.0 0.0 0.4 0.5 0.0 0.5 0.3 0.1 0.6 0.2 0.2 0.0 0.2 1.1 1.4 0.7 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.3 0.6 0.0 0.0 0.2 0.2 0.0 0.4 0.0 0.6 0.0 0.2 1.4 0.1 1.2 6.7 0.1 0.3 0.0 2.4 0.4 0.1 2.8 0.6 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.3 0.4 0.1 1.5 0.2 0.0 1.1 0.7 0.3 0.1 0.0 0.1 0.0 0.0 0.2 0.5 0.4 TASP1 "C20orf13, dJ585I14.2, FLJ20212" ENSG00000089123 "Taspase 1" Q9H6P5 20 13389392-13638932 "Predicted intracellular proteins" "Hydrolase, Protease, Threonine protease" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 136.1;Inhibitory neurons: 131.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030824, HPA030825" Uncertain Approved "Plasma membrane" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA030824: AB_10600327, HPA030825: AB_10601575" "unprognostic (1.29e-1)" "unprognostic (1.68e-1)" "unprognostic (8.61e-2)" "unprognostic (1.20e-1)" "unprognostic (2.47e-1)" "unprognostic (6.46e-2)" "unprognostic (3.44e-3)" "unprognostic (9.85e-2)" "unprognostic (9.85e-2)" "unprognostic (6.95e-2)" "unprognostic (1.59e-1)" "unprognostic (3.13e-2)" "unprognostic (2.21e-1)" "unprognostic (1.04e-1)" "unprognostic (2.70e-1)" "prognostic unfavorable (6.78e-4)" "unprognostic (1.67e-2)" 7.0 4.5 1.0 4.3 1.7 4.9 6.8 1.5 2.9 6.5 3.9 5.2 3.7 6.8 6.0 4.8 8.1 4.5 5.7 1.2 2.7 5.4 4.5 6.0 5.7 1.3 1.7 5.6 5.9 8.7 7.4 6.5 1.0 5.2 5.7 6.4 6.0 4.6 2.9 5.5 4.6 5.1 0.5 5.6 5.6 6.1 2.3 12.5 7.8 4.3 5.2 5.6 6.2 2.9 13.1 7.7 3.1 3.7 3.6 5.6 6.0 5.3 7.6 6.1 7.1 16.0 13.3 5.9 3.6 7.0 6.7 17.2 4.9 18.4 7.1 3.5 5.8 11.8 4.7 20.3 7.4 16.0 4.1 6.3 12.1 6.2 15.0 3.7 6.1 10.4 10.7 0.2 5.4 15.8 30.7 8.7 4.2 11.7 3.5 4.8 12.7 9.1 8.5 9.8 8.3 5.7 8.2 15.8 10.2 4.4 8.3 5.8 5.9 5.7 4.0 5.9 7.6 11.3 16.7 4.2 3.2 3.6 5.5 2.3 4.5 4.9 12.7 6.5 9.0 12.1 12.8 10.0 5.0 9.8 18.6 14.4 2.5 14.8 6.5 19.5 13.3 7.1 1.0 1.7 1.5 2.9 1.2 2.7 1.3 1.7 1.0 0.5 2.3 2.9 10.7 6.4 7.7 31.3 19.6 14.1 13.2 11.1 24.5 14.9 10.0 8.8 6.4 17.2 8.8 5.5 10.4 12.0 13.8 3.9 7.9 12.1 20.1 15.7 10.6 6.6 3.6 7.8 136.1 6.0 12.3 15.9 13.3 9.5 15.2 5.2 3.6 6.4 4.7 11.8 131.0 9.9 4.1 3.0 4.7 4.8 3.4 5.8 10.6 35.6 2.9 6.6 11.3 50.3 49.6 8.6 11.4 3.4 13.3 8.0 5.3 12.2 23.5 17.0 6.6 23.7 17.0 29.3 9.3 18.0 12.1 7.0 12.7 10.2 7.7 8.9 TAZ "BTHS, CMD3A, EFE, EFE2, G4.5, TAZ1, XAP-2" ENSG00000102125 Tafazzin Q16635 X 154411524-154421726 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039557 Approved Approved "Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "HPA039557: AB_10672899" "unprognostic (1.14e-1)" "prognostic favorable (5.70e-4)" "unprognostic (4.94e-3)" "unprognostic (1.43e-1)" "unprognostic (8.29e-2)" "unprognostic (7.84e-2)" "unprognostic (1.56e-2)" "unprognostic (8.21e-3)" "unprognostic (1.69e-1)" "unprognostic (1.62e-1)" "unprognostic (4.68e-2)" "unprognostic (8.39e-2)" "prognostic unfavorable (1.22e-7)" "unprognostic (4.00e-3)" "unprognostic (4.20e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-2)" 19.0 13.8 37.2 8.5 38.1 41.4 17.2 38.1 44.4 18.1 37.0 18.3 9.7 15.1 7.6 21.7 16.6 8.7 43.5 37.0 37.0 22.3 21.9 21.4 17.9 39.3 37.6 18.5 21.3 12.1 14.5 6.6 38.5 17.9 11.7 8.4 13.6 10.2 47.0 18.7 22.9 12.3 37.7 39.2 17.4 4.5 37.9 14.1 18.5 65.6 16.0 18.4 18.4 39.4 24.5 28.6 9.3 11.7 18.3 13.4 18.4 6.9 21.0 15.3 17.1 8.5 29.6 28.2 43.6 16.4 36.6 28.4 17.2 16.6 12.3 25.5 19.6 5.5 20.0 16.4 25.8 12.3 11.8 15.4 35.6 11.7 31.7 12.9 25.6 30.9 12.1 34.9 18.1 17.6 29.0 33.2 2.4 24.9 27.9 21.4 16.2 40.1 24.2 9.0 11.8 17.9 5.3 17.9 26.6 11.1 10.5 16.0 15.5 10.4 11.9 25.5 15.2 55.9 30.6 66.2 13.7 36.6 13.3 5.8 11.1 17.5 12.4 10.4 11.5 12.5 16.6 15.5 14.5 18.7 14.1 12.0 9.9 12.7 7.8 7.9 15.4 9.4 37.2 38.1 38.1 44.4 37.0 37.0 39.3 37.6 38.5 37.7 37.9 39.4 36.2 6.4 11.8 37.2 29.3 10.8 7.9 10.5 14.8 21.6 11.1 15.6 21.1 14.3 13.0 9.2 18.8 5.0 29.7 13.6 5.9 14.7 1.1 6.5 9.6 18.5 6.1 9.7 22.4 16.5 10.1 12.4 23.4 9.6 18.4 19.2 15.0 7.9 24.4 10.1 28.4 15.9 12.2 19.9 16.5 2.0 11.5 20.4 14.2 14.0 21.7 14.2 15.5 23.1 39.7 13.4 12.2 9.1 17.2 8.3 19.6 5.9 8.0 25.6 13.1 12.4 11.3 10.4 3.8 16.8 11.2 2.9 25.6 9.2 15.8 6.7 TBC1D10A "AC004997.C22.2, EPI64, TBC1D10" ENSG00000099992 "TBC1 domain family member 10A" Q9BXI6 22 30291990-30326947 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 116.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007725, HPA008142, HPA076041" Approved Enhanced "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA007725: AB_2667907, HPA008142: AB_1080209, HPA076041: AB_2686772" "unprognostic (3.37e-2)" "unprognostic (2.44e-3)" "unprognostic (1.13e-1)" "unprognostic (1.10e-2)" "unprognostic (2.11e-3)" "unprognostic (1.20e-1)" "unprognostic (4.96e-2)" "unprognostic (5.07e-2)" "unprognostic (4.28e-1)" "unprognostic (6.40e-2)" "unprognostic (1.08e-1)" "unprognostic (2.45e-1)" "unprognostic (3.02e-1)" "unprognostic (7.92e-2)" "unprognostic (3.89e-2)" "unprognostic (1.05e-2)" "unprognostic (7.52e-2)" 22.6 17.0 6.9 10.2 8.2 8.2 23.7 5.8 10.2 29.6 9.3 18.3 8.6 14.7 4.6 44.1 14.9 12.7 11.2 7.5 9.3 21.3 17.9 23.7 17.2 7.4 8.1 21.1 10.8 24.5 19.5 17.5 7.0 21.3 5.5 10.8 23.2 12.9 5.6 45.3 17.3 6.8 6.2 24.2 17.3 21.6 9.7 18.4 19.0 6.9 10.4 19.9 39.9 6.4 18.9 7.1 2.9 9.0 8.4 10.8 23.9 10.7 14.9 11.8 18.7 8.4 7.2 9.5 10.2 17.8 16.2 18.3 4.3 9.9 6.2 7.2 12.4 2.6 6.4 6.0 21.9 3.7 12.9 14.0 15.5 23.4 4.0 12.3 5.5 20.5 5.1 8.8 8.9 22.1 26.9 7.9 1.9 33.9 9.5 12.3 12.4 8.8 11.6 17.9 4.9 3.8 11.0 15.7 24.5 7.8 13.8 2.3 10.8 22.9 10.4 13.1 5.8 8.8 4.2 8.3 15.6 5.6 13.1 37.5 14.9 37.9 26.6 30.1 29.3 13.4 30.9 27.2 21.7 20.7 40.7 34.0 10.6 24.3 45.5 37.5 28.8 28.4 6.9 8.2 5.8 10.2 7.5 9.3 7.4 8.1 7.0 6.2 9.7 6.4 27.8 6.4 3.4 24.8 18.2 49.2 40.2 40.3 32.5 7.8 18.4 12.4 2.7 14.3 23.6 5.5 18.8 57.6 19.5 26.8 23.5 20.1 10.7 8.8 5.4 14.4 10.7 3.0 3.0 10.2 80.6 18.3 19.4 16.4 9.5 20.1 11.0 8.6 27.5 1.7 3.5 14.2 18.3 12.9 46.0 6.9 21.8 15.9 26.6 10.3 78.1 28.1 28.8 2.5 1.0 18.7 18.7 9.1 12.3 24.3 14.9 20.5 6.6 39.3 39.5 7.4 17.1 33.2 13.5 27.6 37.1 116.3 28.0 20.2 11.0 28.3 TEC PSCTK4 ENSG00000135605 "Tec protein tyrosine kinase" P42680 4 48135783-48269838 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 13.9;Glandular and luminal cells: 25.1;granulocytes: 19.6;Plasma cells: 15.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in some" 5 "basophil: 20.7;eosinophil: 13.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 20.7" "Cell line enhanced" "Detected in many" "HEL: 13.5;HMC-1: 20.3;U-266/70: 20.3;U-266/84: 15.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA005733, HPA024657" Approved Supported "Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "HPA005733: AB_1857878, HPA024657: AB_2671637" "unprognostic (7.19e-2)" "unprognostic (1.44e-1)" "unprognostic (1.41e-2)" "unprognostic (4.07e-3)" "unprognostic (4.21e-2)" "unprognostic (8.57e-2)" "unprognostic (3.14e-1)" "unprognostic (1.67e-1)" "unprognostic (8.36e-2)" "prognostic favorable (7.12e-4)" "unprognostic (7.46e-3)" "unprognostic (7.83e-2)" "unprognostic (1.01e-4)" "unprognostic (4.24e-2)" "unprognostic (2.16e-1)" "unprognostic (7.39e-2)" "unprognostic (4.96e-3)" 0.9 1.7 0.1 2.1 0.2 6.1 1.4 0.1 0.4 1.2 1.0 1.3 1.6 1.1 4.2 3.4 1.9 1.1 1.3 0.0 0.4 1.1 2.5 2.0 3.1 1.1 0.3 0.4 0.8 1.2 0.6 1.1 1.1 0.5 1.3 1.8 2.3 1.0 0.6 3.6 1.5 0.8 0.3 1.7 1.1 1.2 0.7 2.0 1.3 0.5 3.3 1.0 1.6 0.2 3.0 0.8 0.0 0.0 0.0 0.0 0.1 0.5 2.2 1.3 2.7 0.0 2.2 1.9 2.0 0.0 0.1 0.6 1.1 0.0 1.8 0.1 0.8 13.5 1.0 0.1 0.0 2.2 20.3 0.0 0.3 1.7 0.0 1.4 0.0 0.6 7.5 0.5 4.1 1.0 1.3 4.9 0.4 1.4 0.8 3.1 2.7 0.0 3.4 0.9 0.0 0.2 0.6 0.3 0.5 1.1 0.7 4.2 0.0 0.0 0.0 2.8 0.0 20.3 15.4 2.6 0.0 3.0 0.1 20.7 0.6 13.3 0.1 0.7 0.3 1.0 0.2 0.5 1.5 0.7 0.5 0.5 0.5 3.6 0.1 0.1 0.1 0.4 0.1 0.2 0.1 0.4 0.0 0.4 1.1 0.3 1.1 0.3 0.7 0.2 0.6 6.4 6.8 0.7 6.8 2.5 1.7 0.2 2.8 0.9 1.7 1.1 1.8 7.2 2.6 0.0 0.0 1.5 3.3 2.1 0.0 1.7 6.4 13.9 1.5 1.2 3.0 12.6 6.7 1.1 0.1 0.8 0.0 25.1 19.6 0.7 0.0 2.9 4.9 0.0 1.6 1.4 4.1 4.6 1.8 2.6 0.0 5.9 1.8 10.3 1.7 6.6 0.0 0.5 0.2 1.0 0.6 0.4 15.4 1.3 3.0 2.0 0.2 3.1 6.6 1.8 0.8 0.7 1.4 9.8 3.0 0.8 3.4 0.3 2.1 1.6 TGFBR1 "ACVRLK4, ALK-5, ALK5, ESS1, MSSE, TBR-i, TBRI" ENSG00000106799 "Transforming growth factor beta receptor 1" P36897 9 99104038-99154192 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 128.4;Late spermatids: 101.7;Microglial cells: 116.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RH-30: 253.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002441, CAB031481, HPA056473" Uncertain Supported "Plasma membrane" "Intracellular and membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane" "CAB002441: AB_564029, CAB031481: AB_2202455, HPA056473: AB_2683144" "unprognostic (2.58e-3)" "unprognostic (1.20e-2)" "unprognostic (3.64e-3)" "unprognostic (2.80e-1)" "unprognostic (8.63e-2)" "unprognostic (3.36e-2)" "unprognostic (1.97e-2)" "unprognostic (1.32e-3)" "unprognostic (1.97e-1)" "unprognostic (1.45e-1)" "unprognostic (8.21e-3)" "unprognostic (1.82e-1)" "unprognostic (1.18e-1)" "unprognostic (1.01e-3)" "unprognostic (3.40e-2)" "unprognostic (3.19e-2)" "unprognostic (1.14e-2)" 15.9 9.9 9.8 18.2 9.3 33.7 15.4 13.2 8.9 19.4 11.8 18.8 11.7 20.6 8.8 15.0 8.5 21.7 8.2 6.8 11.3 22.6 14.8 16.3 13.8 18.4 14.5 13.0 8.3 8.5 7.6 48.8 20.0 17.1 13.4 4.7 8.3 16.8 8.7 6.2 9.3 33.0 18.0 16.5 18.4 18.3 17.5 11.2 11.2 13.2 13.6 22.5 8.4 27.9 13.7 19.5 115.5 36.1 26.2 19.3 17.4 44.1 47.8 40.7 44.9 19.9 9.3 29.7 13.4 34.6 32.1 30.4 39.6 34.1 54.0 77.1 12.3 43.9 20.7 17.8 43.2 27.2 102.8 40.2 35.4 62.8 29.5 25.2 7.4 10.9 62.4 12.1 55.4 20.3 4.0 31.0 24.7 12.2 11.5 11.0 253.1 12.5 9.9 3.8 31.1 36.2 34.3 150.2 46.4 47.3 28.1 36.6 13.6 29.8 25.5 129.3 27.3 12.1 13.4 20.0 62.5 45.9 26.2 16.2 2.4 9.5 7.8 1.6 6.7 1.6 3.3 5.8 2.0 1.2 3.2 6.2 4.9 4.3 2.0 1.4 2.4 2.2 9.8 9.3 13.2 8.9 6.8 11.3 18.4 14.5 20.0 18.0 17.5 27.9 13.5 6.4 8.8 18.9 18.9 23.6 7.4 19.9 44.3 8.0 18.9 11.7 7.6 4.3 12.8 60.7 0.0 23.0 37.3 5.0 0.0 18.8 128.4 6.4 22.7 17.6 9.6 7.4 14.2 31.2 6.7 36.0 9.2 9.3 29.9 19.5 6.4 12.7 49.4 0.0 8.6 7.3 8.2 32.4 52.5 101.7 9.6 39.7 35.6 116.2 24.3 3.1 35.0 45.8 21.1 33.8 4.2 13.5 11.9 18.4 3.6 13.8 5.0 2.0 32.9 21.8 20.9 11.0 12.7 25.6 16.2 19.4 25.4 7.6 8.3 11.5 TGFBR2 "MFS2, TBR-ii, TBRII" ENSG00000163513 "Transforming growth factor beta receptor 2" P37173 3 30606601-30694142 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Apoptosis, Differentiation, Growth regulation" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Cancer-related genes, Craniosynostosis, Disease variant, FDA approved drug targets, Hereditary nonpolyposis colorectal cancer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 391.5;Endothelial cells: 236.4;Hepatic stellate cells: 478.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 313.6;ASC TERT1: 472.3;HSkMC: 430.0;LHCN-M2: 381.7;TIME: 418.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB073537 Supported "Plasma membrane" NA NA 810000 "Cluster 5: Granulocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "CAB073537: " "unprognostic (1.74e-1)" "unprognostic (1.84e-2)" "unprognostic (3.70e-1)" "unprognostic (3.02e-2)" "unprognostic (1.92e-1)" "unprognostic (2.26e-1)" "unprognostic (1.96e-1)" "unprognostic (1.62e-1)" "unprognostic (1.40e-1)" "unprognostic (2.24e-2)" "unprognostic (7.36e-2)" "unprognostic (1.12e-1)" "unprognostic (1.65e-2)" "unprognostic (4.72e-2)" "unprognostic (1.81e-2)" "unprognostic (8.81e-2)" "unprognostic (8.02e-2)" 230.0 56.1 16.5 73.8 12.9 29.4 145.7 13.8 19.3 90.0 30.6 96.0 44.2 69.1 18.2 44.9 69.6 91.9 95.2 10.6 13.4 67.9 59.1 148.0 70.1 17.6 16.5 26.6 52.0 59.0 16.9 81.6 16.7 44.1 54.1 2.1 49.2 60.8 31.1 39.1 77.7 107.2 17.3 111.1 63.4 7.8 21.5 49.7 91.8 62.2 60.7 98.0 55.1 17.2 16.6 100.2 5.3 0.1 313.6 472.3 15.9 83.9 116.1 28.5 27.7 22.9 86.6 2.2 298.2 117.2 32.2 33.3 4.0 125.4 42.0 7.0 8.9 10.1 10.7 104.5 128.5 14.9 76.6 430.0 93.6 126.3 114.4 117.0 296.0 10.9 1.8 0.0 381.7 1.3 16.2 10.5 2.2 75.7 39.8 14.1 36.4 2.1 113.5 40.5 0.1 5.6 24.9 6.1 22.0 6.6 0.0 14.0 418.6 134.7 33.2 61.4 32.0 2.8 0.3 12.5 80.1 16.1 55.8 9.0 3.0 11.5 3.4 3.1 3.3 4.5 4.8 3.3 2.6 6.4 16.6 7.3 13.1 1.9 8.0 6.6 0.7 3.8 16.5 12.9 13.8 19.3 10.6 13.4 17.6 16.5 16.7 17.3 21.5 17.2 391.5 144.2 99.7 0.7 77.0 37.3 18.9 23.5 39.9 5.1 23.7 24.1 84.5 50.1 39.5 27.6 0.0 6.8 85.3 10.5 3.9 13.1 2.5 28.3 57.5 236.4 8.4 20.4 0.4 15.8 5.1 129.2 39.3 30.8 29.8 0.7 478.0 55.5 30.4 0.0 1.0 12.4 22.4 147.0 58.0 3.8 32.9 67.9 30.2 170.5 47.5 0.2 56.7 6.0 2.4 37.6 12.1 47.4 37.5 8.6 13.6 7.2 14.7 1.2 32.9 60.8 53.4 0.3 1.2 8.0 30.5 3.7 68.2 1.7 14.5 10.8 THBS1 "THBS, THBS-1, TSP, TSP-1, TSP1" ENSG00000137801 "Thrombospondin 1" P07996 15 39581079-39599466 "Cancer-related genes, Candidate cardiovascular disease genes, Plasma proteins, Predicted secreted proteins" "Cell adhesion, Unfolded protein response" Heparin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 279.5;Granulosa cells: 228.3;Macrophages: 598.0;Smooth muscle cells: 283.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "eosinophil: 15.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 2610.2;HUVEC TERT2: 2494.4;LHCN-M2: 1863.4;TIME: 3552.9" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 20.6" "CAB033678, HPA059756" Approved Approved "Plasma membrane" "Secreted to extracellular matrix" NA NA 16000000000 1400000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "CAB033678: AB_793044, HPA059756: AB_2684121" "unprognostic (1.72e-2)" "unprognostic (9.55e-3)" "unprognostic (7.49e-2)" "unprognostic (3.31e-1)" "unprognostic (4.34e-2)" "unprognostic (1.03e-3)" "unprognostic (3.60e-1)" "unprognostic (1.53e-2)" "unprognostic (1.22e-1)" "unprognostic (2.07e-1)" "unprognostic (6.40e-2)" "unprognostic (9.16e-2)" "prognostic unfavorable (8.47e-5)" "prognostic unfavorable (8.50e-4)" "unprognostic (1.00e-1)" "unprognostic (9.25e-3)" "unprognostic (1.48e-3)" 364.3 72.5 1.7 394.0 3.7 114.7 95.1 2.1 11.3 66.7 27.3 166.4 24.8 161.3 3.5 49.1 142.6 275.2 98.3 2.2 2.1 70.9 129.4 309.2 32.3 10.8 4.4 76.3 69.1 7.0 26.8 99.0 10.8 89.8 85.6 0.4 137.3 12.0 16.2 35.4 83.5 243.6 0.9 79.8 150.5 2.2 14.3 12.0 34.0 4.3 7.1 396.3 36.2 2.1 171.9 62.7 49.0 17.8 199.4 233.9 0.7 1025.7 861.6 283.6 185.5 185.0 135.7 1.0 348.4 2610.2 54.4 621.0 2.2 516.1 145.0 43.4 0.5 46.6 35.0 46.9 44.4 0.3 13.2 524.9 37.2 237.2 535.1 1123.6 2494.4 1.6 1.5 1.7 1863.4 14.7 0.8 3.6 8.9 17.7 20.3 0.7 125.7 1.3 430.6 472.6 0.6 0.4 300.7 16.4 18.5 60.8 178.6 3.3 3552.9 972.6 221.0 1141.1 1146.6 2.4 1.8 2.0 33.0 0.8 1064.4 0.3 8.7 15.7 0.7 0.8 2.7 0.0 0.4 0.5 0.5 0.1 0.1 0.1 1.5 7.8 0.1 0.4 0.0 10.5 1.7 3.7 2.1 11.3 2.2 2.1 10.8 4.4 10.8 0.9 14.3 2.1 19.0 25.6 19.6 0.7 4.9 95.7 131.2 37.6 181.6 0.1 66.8 69.8 48.7 18.6 19.9 69.9 6.2 1.9 8.2 144.5 0.0 52.1 0.2 64.9 127.7 79.2 3.6 0.0 0.9 127.5 2.5 279.5 15.8 38.2 162.7 228.3 44.6 7.4 6.3 0.0 1.3 46.4 48.8 105.9 97.9 0.3 1.8 598.0 39.2 13.1 5.9 0.1 3.1 0.0 0.1 183.9 55.1 0.4 5.9 79.2 8.5 48.3 11.9 1.5 6.6 59.0 283.8 0.2 0.3 51.8 51.0 2.1 19.5 10.8 67.8 42.1 THEGL ENSG00000249693 "Theg spermatid protein like" P0DJG4 4 56530606-56603507 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 6 "testis: 3.5" "Group enriched" "Detected in some" 6 "Early spermatids: 27.3;Late spermatids: 20.0" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Low region specificity" "Detected in single" "HPA066627, HPA068093" Uncertain Approved "Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA066627: , HPA068093: AB_2685951" "unprognostic (4.33e-2)" "unprognostic (2.88e-3)" "unprognostic (7.97e-2)" "unprognostic (1.19e-1)" "unprognostic (3.69e-2)" "unprognostic (3.26e-1)" "unprognostic (1.90e-2)" "unprognostic (6.55e-2)" "unprognostic (1.61e-1)" "unprognostic (1.37e-1)" "unprognostic (4.70e-2)" "unprognostic (4.49e-2)" "unprognostic (1.73e-1)" "unprognostic (8.41e-2)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.1 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 3.5 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.5 0.0 0.1 0.1 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.1 0.3 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.3 0.0 0.3 0.1 0.0 3.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 27.3 0.0 0.0 0.1 0.0 1.3 2.5 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 20.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.4 0.1 0.7 0.0 0.0 0.0 0.1 0.1 0.0 TIMD4 TIM4 ENSG00000145850 "T cell immunoglobulin and mucin domain containing 4" Q96H15 5 156919292-156963226 "Plasma proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "lymphoid tissue: 55.3;testis: 144.0" "Group enriched" "Detected in some" 23 "Early spermatids: 1336.2;Late spermatids: 1946.7" "Cancer enriched" "Detected in some" 10 "renal cancer: 6.2" "Low region specificity" "Detected in single" "Group enriched" "Detected in some" 5 "memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.4;naive CD4 T-cell: 1.6;naive CD8 T-cell: 1.6;T-reg: 4.0" "Lineage enriched" "Detected in single" 18 "T-cells: 4.0" "Group enriched" "Detected in some" 18 "U-266/70: 96.7;U-266/84: 28.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015625, CAB026027" Approved Approved "Plasma membrane" NA NA 32000000 "Cluster 35: T-regs - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 29: U-266 - Adaptive immune response" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" "CAB026027: , HPA015625: AB_1858018" "unprognostic (2.92e-1)" "unprognostic (1.06e-2)" "unprognostic (1.73e-1)" "unprognostic (2.31e-1)" "unprognostic (1.80e-1)" "unprognostic (3.01e-2)" "unprognostic (1.10e-1)" "unprognostic (3.11e-1)" "unprognostic (3.42e-1)" "unprognostic (8.42e-2)" "unprognostic (1.10e-1)" "unprognostic (6.90e-2)" "prognostic favorable (3.37e-4)" "unprognostic (1.31e-2)" "unprognostic (4.07e-1)" "unprognostic (3.27e-2)" "unprognostic (2.08e-2)" 14.9 0.4 0.4 6.9 0.3 16.1 0.4 0.3 1.4 0.1 1.8 1.1 0.4 0.0 1.3 0.1 0.1 1.3 0.7 0.5 0.4 3.4 16.3 1.6 55.3 0.5 0.4 0.0 0.2 0.1 0.0 5.0 0.5 0.3 0.8 0.0 0.2 0.0 0.1 0.3 1.7 1.0 0.3 8.0 0.2 144.0 0.5 22.4 1.1 0.0 17.4 4.8 0.1 0.5 0.1 3.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.6 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 96.7 28.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 1.3 2.4 0.0 0.0 1.6 1.6 0.0 0.0 0.0 0.0 4.0 0.7 0.4 0.3 0.3 1.4 0.5 0.4 0.5 0.4 0.5 0.3 0.5 0.5 0.1 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.4 0.4 5.9 0.1 1336.2 0.3 0.0 0.5 0.0 0.0 0.4 0.0 0.7 0.1 0.5 0.0 0.0 0.0 0.7 0.3 46.4 0.0 0.3 0.0 0.0 69.4 1.9 1946.7 14.9 1.9 0.0 2.8 0.0 0.0 1.0 0.0 0.3 0.0 0.0 10.9 6.5 0.0 0.0 0.8 0.0 0.0 13.1 0.0 0.1 16.6 8.1 0.0 0.0 0.3 1.7 0.1 0.1 0.0 TMEM229A ENSG00000234224 "Transmembrane protein 229A" B2RXF0 7 124030921-124033067 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.6;intestine: 8.4;testis: 5.3" "Cell type enhanced" "Detected in some" "Astrocytes: 9.4;Bipolar cells: 3.7;Oligodendrocytes: 11.4;Proximal enterocytes: 10.0" "Cancer enhanced" "Detected in some" "glioma: 2.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 44 "SH-SY5Y: 130.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056391 Uncertain Approved "Plasma membrane" NA NA "Cluster 45: Intestine - Brush border" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA056391: AB_2683114" "unprognostic (2.52e-2)" "unprognostic (3.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.50e-1)" "unprognostic (2.89e-2)" "unprognostic (8.21e-2)" "unprognostic (4.74e-2)" "unprognostic (2.31e-1)" "unprognostic (4.31e-3)" 0.0 1.0 7.5 0.0 11.0 0.0 0.0 9.8 9.0 0.1 2.5 0.1 8.4 0.1 0.4 0.0 0.6 0.0 0.2 7.7 9.6 0.0 0.0 0.0 0.0 9.1 12.6 0.2 0.0 0.8 0.9 0.1 9.0 0.2 0.1 0.1 0.4 0.0 0.0 0.0 3.9 0.1 7.9 0.1 1.8 5.3 10.2 0.0 0.0 0.0 0.0 0.3 0.0 11.7 0.0 0.0 1.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 130.7 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 11.0 9.8 9.0 7.7 9.6 9.1 12.6 9.0 7.9 10.2 11.7 0.0 0.0 0.0 9.4 0.0 0.0 0.1 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.9 0.2 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.0 1.1 0.3 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 1.2 0.0 2.0 11.4 0.0 2.5 0.0 0.0 0.1 10.0 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.3 0.0 1.2 0.7 0.2 TMPRSS15 "ENTK, MGC133046, PRSS7" ENSG00000154646 "Transmembrane serine protease 15" P98073 21 18269116-18485879 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Hydrolase, Protease, Serine protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 512 "intestine: 979.8" "Cell type enriched" "Detected in some" 5 "Proximal enterocytes: 28.0" "Group enriched" "Detected in some" 12 "liver cancer: 0.7;pancreatic cancer: 1.5;stomach cancer: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 19 "U-138 MG: 50.8;U-87 MG: 141.3" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "olfactory bulb: 5.0;spinal cord: 1.8" "HPA015611, HPA034857, HPA072934" Enhanced Approved "Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "HPA015611: AB_1855791, HPA034857: , HPA072934: AB_2732214" "unprognostic (9.26e-2)" "unprognostic (4.14e-1)" "unprognostic (3.52e-1)" "unprognostic (8.33e-2)" "unprognostic (1.19e-1)" "unprognostic (7.20e-2)" "unprognostic (4.70e-2)" "unprognostic (6.35e-2)" "unprognostic (5.92e-2)" 0.0 0.0 0.9 0.2 0.7 0.0 0.0 1.9 1.7 0.0 0.0 0.2 979.8 0.2 0.0 0.1 0.0 0.1 0.1 0.7 0.6 0.0 0.0 0.0 0.7 0.2 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.2 21.8 0.0 0.0 0.0 0.4 1.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 1.8 0.2 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.1 4.9 0.0 0.0 0.0 0.4 0.1 0.1 0.0 0.3 0.0 4.6 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 50.8 0.0 0.3 0.0 0.9 0.0 0.2 141.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.9 0.7 1.9 1.7 0.7 0.6 0.2 0.6 0.1 0.0 0.4 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 1.9 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.2 0.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 4.0 0.0 TMPRSS2 PRSS10 ENSG00000184012 "Transmembrane serine protease 2" O15393 21 41464300-41531116 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 280.4;stomach 1: 146.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 404.8;Gastric mucus-secreting cells: 155.4;Paneth cells: 368.3;Prostatic glandular cells: 203.4;Proximal enterocytes: 159.6;Urothelial cells: 166.6" "Cancer enriched" "Detected in many" 7 "prostate cancer: 250.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 22.8;MCF7: 10.5;OE19: 35.9;RT4: 57.8;SK-BR-3: 11.7" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA034493, HPA035787" Enhanced Supported "Plasma membrane" "Secreted in other tissues" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA034493: , HPA035787: AB_2674782" "unprognostic (4.80e-3)" "unprognostic (3.49e-1)" "unprognostic (2.16e-1)" "prognostic favorable (2.56e-4)" "unprognostic (1.72e-1)" "unprognostic (1.05e-2)" "unprognostic (4.28e-2)" "unprognostic (1.51e-3)" "unprognostic (9.43e-2)" "unprognostic (9.02e-3)" "unprognostic (6.24e-2)" "unprognostic (6.43e-2)" "prognostic favorable (7.86e-6)" "unprognostic (2.00e-2)" "unprognostic (1.68e-1)" "unprognostic (1.41e-1)" "unprognostic (2.15e-2)" 0.6 0.2 0.4 13.9 0.4 0.1 20.1 0.2 0.4 5.0 3.1 104.0 78.5 1.0 2.8 36.1 10.7 24.1 0.2 0.3 0.3 47.7 33.5 39.9 0.2 0.4 0.3 0.2 111.4 4.0 1.5 0.2 0.3 280.4 78.0 0.2 76.2 7.7 0.1 7.3 89.6 3.3 0.1 0.2 146.2 1.5 0.3 0.8 19.2 0.1 10.2 35.7 7.6 0.5 0.1 0.0 0.1 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.1 22.8 3.3 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.1 3.7 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.3 0.0 0.1 0.1 0.0 10.5 0.3 1.0 2.3 35.9 0.2 0.1 0.0 2.6 1.3 57.8 0.2 0.7 0.3 11.7 0.3 0.4 8.8 0.0 0.0 0.1 0.6 0.6 0.1 0.0 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.2 0.4 0.3 0.3 0.4 0.3 0.3 0.1 0.3 0.5 0.1 51.3 109.8 0.0 1.7 0.3 30.9 6.8 0.0 0.0 34.0 25.8 0.6 32.9 42.1 47.8 0.0 0.7 1.1 404.8 23.5 39.2 21.3 7.4 0.5 1.3 18.0 2.7 0.2 60.4 0.1 1.0 155.4 5.8 7.0 0.0 0.4 32.0 0.1 0.0 0.1 84.1 44.7 0.3 0.3 4.8 0.0 2.0 10.6 0.0 0.6 0.0 0.0 0.0 0.0 65.1 368.3 0.0 0.0 203.4 159.6 3.8 36.6 0.0 0.0 1.6 2.0 0.4 1.4 2.1 0.1 0.3 1.1 0.0 105.7 166.6 TNFRSF8 "CD30, D1S166E, KI-1" ENSG00000120949 "TNF receptor superfamily member 8" P28908 1 12063303-12144207 "Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adipose tissue: 5.3" "Cell type enhanced" "Detected in some" "Adipocytes: 7.1;Early spermatids: 3.5;Kupffer cells: 5.3;Langerhans cells: 3.3;Late spermatids: 9.8;Macrophages: 5.8;monocytes: 5.1" "Cancer enriched" "Detected in some" 12 "testis cancer: 9.3" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Group enriched" "Detected in many" 4 "intermediate monocyte: 59.4;non-classical monocyte: 96.6" "Lineage enriched" "Detected in many" 5 "monocytes: 96.6" "Cell line enriched" "Detected in some" 21 "HDLM-2: 552.9" "Region enhanced" "Detected in many" "hypothalamus: 5.5" "CAB000016, HPA014823, HPA032081, HPA032082" Approved Supported "Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "CAB000016: AB_563546, HPA014823: , HPA032081: AB_2674141, HPA032082: AB_2674142" "unprognostic (1.07e-2)" "unprognostic (2.06e-2)" "unprognostic (2.52e-2)" "unprognostic (5.98e-2)" "unprognostic (2.50e-1)" "unprognostic (1.46e-3)" "unprognostic (2.19e-1)" "unprognostic (3.93e-2)" "unprognostic (1.18e-1)" "unprognostic (9.18e-3)" "unprognostic (1.86e-1)" "unprognostic (2.06e-1)" "unprognostic (3.17e-8)" "unprognostic (3.31e-1)" "unprognostic (8.56e-2)" "unprognostic (2.07e-1)" "unprognostic (2.31e-2)" 5.3 0.0 0.1 3.1 2.3 0.6 3.5 0.0 0.6 0.2 0.1 0.4 0.0 0.8 0.0 0.2 0.9 0.6 1.9 0.0 0.2 0.3 0.0 0.9 1.2 0.2 0.1 0.2 0.1 0.0 0.0 0.7 0.2 0.2 0.1 0.0 0.3 0.1 0.9 0.9 0.7 0.5 0.1 1.4 2.5 1.4 0.7 1.0 0.1 1.2 1.1 0.9 0.3 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.4 0.0 0.1 0.8 11.7 0.0 0.0 0.0 0.0 0.0 0.1 552.9 0.1 0.0 0.1 0.0 0.0 10.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 3.7 26.3 1.5 0.0 0.0 1.5 0.2 21.7 0.0 0.4 0.0 0.0 8.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.2 0.1 0.0 1.4 1.4 0.2 0.0 0.1 0.1 0.3 0.0 0.0 0.0 17.6 1.0 0.1 59.4 0.3 0.1 0.1 0.0 8.7 0.0 0.0 0.0 18.3 0.0 96.6 2.3 0.8 8.5 0.1 2.3 0.0 0.6 0.0 0.2 0.2 0.1 0.2 0.1 0.7 0.2 7.1 0.0 0.0 0.3 0.4 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 3.5 0.1 0.5 2.2 0.0 0.0 0.6 0.0 0.2 1.1 2.6 0.1 0.0 0.1 2.2 0.1 1.5 0.0 0.5 0.0 0.0 5.3 3.3 9.8 0.3 5.8 0.0 1.0 5.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 1.3 1.0 0.0 0.1 0.3 0.4 0.2 0.0 0.1 TNKS1BP1 "FLJ45975, KIAA1741, TAB182" ENSG00000149115 "Tankyrase 1 binding protein 1" Q9C0C2 11 57299638-57324952 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Suprabasal keratinocytes: 88.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA037929, HPA037930" Enhanced Uncertain "Plasma membrane" NA NA 180000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" "HPA037929: AB_10672613, HPA037930: AB_2675745" "unprognostic (7.31e-2)" "unprognostic (1.66e-2)" "unprognostic (5.38e-2)" "unprognostic (2.25e-1)" "unprognostic (3.13e-1)" "unprognostic (9.17e-2)" "unprognostic (2.47e-2)" "unprognostic (7.90e-2)" "unprognostic (4.27e-1)" "unprognostic (2.67e-2)" "unprognostic (4.22e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (2.11e-8)" "unprognostic (2.46e-1)" "unprognostic (2.31e-2)" "unprognostic (2.41e-1)" "unprognostic (3.07e-1)" 62.7 27.3 11.8 17.3 10.2 3.3 41.9 4.6 9.4 43.3 18.0 23.6 28.8 40.3 30.3 55.4 35.3 28.1 23.3 11.3 9.2 14.7 31.6 40.3 6.6 9.6 8.8 32.2 30.9 18.9 17.1 29.5 7.2 33.6 16.2 3.3 44.2 40.2 67.2 83.0 26.6 29.4 4.9 18.1 52.8 10.1 11.0 22.3 25.0 29.9 14.3 38.5 45.6 6.7 89.5 58.7 41.2 33.6 127.8 97.1 31.0 61.5 113.8 46.3 42.5 26.1 59.5 2.0 38.5 101.2 49.6 151.7 31.4 105.3 30.1 34.2 10.4 11.5 38.2 12.2 86.6 14.4 4.3 96.8 123.5 70.9 54.6 57.5 60.0 12.4 13.2 9.3 65.3 45.4 11.0 14.7 45.8 46.5 45.9 16.9 57.2 25.9 53.5 116.6 14.6 22.6 81.5 121.5 44.3 29.0 182.2 11.9 115.1 47.3 45.8 56.6 35.2 15.0 4.1 11.3 107.0 4.0 23.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 11.8 10.2 4.6 9.4 11.3 9.2 9.6 8.8 7.2 4.9 11.0 6.7 38.1 12.8 35.4 12.7 1.9 83.6 28.0 61.9 40.9 4.8 24.8 23.9 7.9 38.6 39.0 44.1 2.1 16.8 1.3 27.3 0.0 31.8 1.8 18.5 25.4 25.9 18.0 7.4 7.2 22.3 3.2 31.2 49.5 38.4 2.5 3.7 19.6 46.0 3.9 8.4 4.8 25.8 18.3 1.5 25.4 2.9 48.1 3.8 17.8 1.9 0.7 4.0 0.0 4.5 2.4 38.8 14.3 49.2 0.6 41.2 18.2 2.4 15.4 1.3 32.9 41.2 26.9 1.5 3.0 68.9 88.2 24.5 2.3 23.4 14.5 36.8 TPRN "C9orf75, DFNB79, FLJ90254" ENSG00000176058 Taperin Q4KMQ1 9 137191617-137204193 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Hearing "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 56.4;pancreas: 91.4" "Cell type enhanced" "Detected in all" "Distal enterocytes: 177.7;Proximal enterocytes: 95.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 61.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 23.6" "HPA020899, HPA076667" Approved Approved "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 22: Non-specific - Unknown function" "Cluster 6: T47d - Mammary gland" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "HPA020899: AB_1845835, HPA076667: " "unprognostic (5.41e-2)" "prognostic favorable (2.13e-4)" "unprognostic (2.94e-1)" "unprognostic (9.28e-2)" "unprognostic (1.68e-1)" "unprognostic (2.61e-2)" "unprognostic (3.59e-3)" "unprognostic (8.20e-2)" "unprognostic (9.96e-2)" "unprognostic (1.21e-1)" "unprognostic (1.89e-2)" "unprognostic (4.77e-2)" "prognostic favorable (5.16e-9)" "unprognostic (1.96e-3)" "unprognostic (6.35e-2)" "unprognostic (1.51e-1)" "unprognostic (5.44e-2)" 3.7 5.1 24.3 4.4 37.8 2.7 4.8 29.9 33.1 5.2 15.1 25.4 22.0 4.7 0.9 20.5 5.1 3.2 10.7 23.5 23.7 19.1 24.3 8.1 2.4 33.1 32.4 6.4 91.4 2.5 6.0 3.3 28.2 8.0 6.9 1.7 11.8 3.4 6.2 15.6 26.0 1.5 20.8 5.0 29.3 9.3 31.9 2.0 5.5 3.1 1.5 7.8 6.9 56.4 10.2 11.4 3.8 17.0 5.2 5.5 30.1 7.0 4.3 7.0 3.9 38.5 12.1 18.6 10.1 3.6 9.2 30.4 7.9 3.9 0.9 11.9 11.1 8.7 17.5 25.5 7.9 13.5 10.8 4.7 7.5 6.2 4.3 4.6 4.5 8.2 16.1 6.4 2.1 61.9 8.9 29.0 13.5 55.5 14.8 26.3 9.1 28.4 15.9 21.0 24.4 8.9 10.8 49.6 13.0 2.9 57.8 21.0 5.0 12.7 6.0 20.1 15.1 5.3 11.0 9.7 9.1 12.1 7.2 0.0 0.8 0.0 0.3 0.8 0.1 0.3 0.3 0.5 0.6 0.3 0.1 0.3 0.0 0.8 0.4 0.6 0.6 0.2 24.3 37.8 29.9 33.1 23.5 23.7 33.1 32.4 28.2 20.8 31.9 56.4 4.6 19.2 5.5 6.2 3.5 1.8 1.3 2.6 2.2 19.3 13.2 9.5 7.6 15.7 2.6 16.5 6.2 5.4 8.4 177.7 7.9 8.0 3.1 7.6 4.1 2.9 9.0 7.4 3.3 45.4 1.3 3.0 15.3 9.6 1.3 8.7 3.9 19.5 3.6 11.8 3.8 46.0 6.1 2.8 1.6 5.3 3.4 5.2 5.4 1.0 2.8 12.4 1.0 2.5 30.4 15.3 39.7 4.5 1.9 3.3 95.9 20.0 2.3 7.3 6.6 3.2 4.5 2.7 4.4 5.8 2.8 1.9 4.5 10.3 36.7 1.7 TREML4 TLT4 ENSG00000188056 "Triggering receptor expressed on myeloid cells like 4" Q6UXN2 6 41228339-41238882 "Predicted membrane proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in single" "choroid plexus: 1.5" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "eosinophil: 4.5;neutrophil: 8.1" "Lineage enriched" "Detected in many" 5 "granulocytes: 8.1" "Cell line enriched" "Detected in single" 6 "HEL: 1.1" "Not detected" "Not detected" HPA065044 Uncertain Approved "Plasma membrane" "Secreted - unknown location" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 36: HEL - Hemostasis" "Cluster 41: Macrophages - Immune response" "Plasma membrane" "HPA065044: AB_2685411" "unprognostic (1.49e-1)" "unprognostic (1.51e-1)" "unprognostic (5.58e-2)" "unprognostic (2.07e-1)" "unprognostic (2.12e-1)" "unprognostic (1.03e-1)" "unprognostic (5.50e-2)" "unprognostic (9.50e-3)" "unprognostic (1.18e-4)" "unprognostic (1.05e-3)" "unprognostic (1.32e-1)" "unprognostic (5.26e-2)" "unprognostic (1.21e-2)" 0.0 0.0 0.0 0.3 0.2 0.7 0.0 0.0 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 4.5 0.0 0.4 0.0 0.1 0.0 0.0 0.5 0.9 0.0 0.0 8.1 0.0 0.4 0.7 0.0 0.4 0.0 0.2 0.0 0.4 0.1 0.2 0.2 0.1 0.1 0.2 0.2 0.6 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TRPV2 "VRL, VRL-1, VRL1" ENSG00000187688 "Transient receptor potential cation channel subfamily V member 2" Q9Y5S1 17 16415571-16437003 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "granulocytes: 50.0;Hofbauer cells: 50.6;monocytes: 39.4;NK-cells: 49.4" "Cancer enriched" "Detected in all" 8 "melanoma: 59.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 78.8;fHDF/TERT166: 108.4;HMC-1: 89.0;SK-MEL-30: 94.7;TIME: 84.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA044993 Uncertain Supported "Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "HPA044993: AB_10960889" "unprognostic (1.57e-1)" "unprognostic (4.34e-3)" "unprognostic (2.05e-2)" "unprognostic (1.58e-2)" "unprognostic (2.85e-2)" "unprognostic (6.16e-3)" "unprognostic (5.25e-2)" "unprognostic (1.25e-1)" "unprognostic (8.40e-3)" "unprognostic (2.43e-1)" "unprognostic (3.11e-2)" "unprognostic (1.02e-1)" "prognostic unfavorable (1.19e-6)" "unprognostic (7.94e-2)" "prognostic unfavorable (5.53e-4)" "unprognostic (8.07e-2)" "unprognostic (1.23e-1)" 17.1 20.5 6.2 18.3 8.0 22.8 10.4 5.7 7.6 7.9 3.9 7.0 6.6 7.6 1.8 5.3 7.3 8.5 11.2 6.1 9.8 4.7 4.0 30.2 24.6 10.6 15.4 7.8 6.3 8.9 1.6 20.1 17.2 6.0 6.2 1.0 4.5 2.6 3.9 6.5 10.7 11.8 7.1 23.7 5.9 2.0 7.3 15.7 6.2 5.5 16.2 10.7 7.2 8.0 0.3 1.6 0.0 0.0 25.6 78.8 4.9 8.3 9.4 9.1 8.9 0.3 0.3 9.6 2.2 108.4 7.8 0.2 0.2 0.0 5.1 43.0 0.7 10.7 0.0 26.1 30.0 14.8 89.0 35.2 0.0 54.0 0.7 4.1 3.8 12.9 37.2 26.0 43.4 0.5 19.1 20.5 0.1 0.1 0.2 11.3 0.3 4.3 40.6 1.1 1.2 0.1 0.0 0.0 94.7 41.0 0.0 12.7 84.9 0.2 0.3 0.3 1.1 0.1 0.3 5.1 8.2 21.6 12.6 60.8 26.6 35.8 63.4 52.8 55.5 19.2 46.0 59.3 58.7 20.3 25.7 44.8 6.8 63.2 49.4 51.3 49.9 43.1 6.2 8.0 5.7 7.6 6.1 9.8 10.6 15.4 17.2 7.1 7.3 8.0 15.8 0.0 5.3 1.0 11.1 2.8 0.1 0.0 0.0 0.6 0.5 0.4 1.1 1.5 0.6 0.0 0.0 2.2 29.3 0.0 0.0 0.2 0.3 0.4 0.1 12.3 0.0 6.7 3.3 3.6 2.3 11.0 1.1 0.1 50.0 16.7 8.9 0.4 50.6 0.0 2.6 0.0 0.0 19.5 18.2 0.0 1.8 28.7 28.4 4.7 39.4 0.3 49.4 0.5 0.5 4.7 0.1 4.5 15.1 0.0 0.0 0.1 0.8 0.6 26.3 7.9 23.6 1.3 5.9 0.4 1.7 16.1 26.8 2.8 0.0 0.1 TSPAN16 "TM-8, TM4-B, TM4SF16" ENSG00000130167 "Tetraspanin 16" Q9UKR8 19 11296139-11326996 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 26 "testis: 134.7" "Cell type enriched" "Detected in some" 5 "Late spermatids: 4868.3" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "basophil: 16.6;eosinophil: 19.1;neutrophil: 37.4" "Lineage enriched" "Detected in many" 17 "granulocytes: 37.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA076551 Enhanced Approved "Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA076551: " "unprognostic (1.06e-1)" "unprognostic (2.82e-2)" "unprognostic (1.73e-2)" "unprognostic (4.74e-3)" "unprognostic (1.53e-1)" "unprognostic (2.06e-3)" "unprognostic (1.37e-1)" "unprognostic (2.21e-1)" "unprognostic (7.68e-2)" "unprognostic (1.90e-1)" "unprognostic (8.69e-4)" "unprognostic (8.81e-8)" "unprognostic (1.98e-1)" "unprognostic (1.12e-1)" "unprognostic (1.95e-3)" "unprognostic (2.67e-1)" 0.0 0.0 0.2 0.2 0.1 5.1 0.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 134.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 16.6 2.2 19.1 0.0 0.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 37.4 0.0 0.4 0.0 0.0 0.3 0.2 0.1 0.3 0.4 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 892.5 0.0 0.1 1.6 0.0 0.0 1.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.2 4868.3 15.5 1.5 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.0 0.4 20.9 12.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TSPO2 "BZRPL1, dJ34B21.2" ENSG00000112212 "Translocator protein 2" Q5TGU0 6 41042467-41044337 "Predicted membrane proteins, Transporters" Transport Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 30 "bone marrow: 50.1" "Cell type enriched" "Detected in some" 115 "Erythroid cells: 253.9" "Cancer enhanced" "Detected in some" "liver cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "OE19: 11.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA060691, HPA066996" Enhanced "Plasma membrane" NA NA "Cluster 67: Neutrophils - Humoral immune response" "Cluster 21: OE19 - Mitochondria" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "HPA060691: , HPA066996: AB_2685761" "unprognostic (1.89e-3)" "unprognostic (8.35e-3)" "unprognostic (2.57e-3)" "unprognostic (2.29e-2)" "unprognostic (1.63e-1)" "unprognostic (2.66e-2)" "unprognostic (6.61e-3)" "unprognostic (2.29e-1)" "unprognostic (3.37e-1)" "unprognostic (2.89e-1)" "unprognostic (2.71e-1)" "unprognostic (4.92e-2)" "unprognostic (1.86e-2)" "unprognostic (2.70e-2)" "unprognostic (1.16e-1)" "unprognostic (5.37e-2)" "unprognostic (1.76e-2)" 0.0 0.0 0.1 0.1 0.6 50.1 0.0 0.1 0.7 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 0.1 0.4 0.5 0.6 0.2 0.1 0.8 0.4 0.1 0.1 0.0 0.0 1.2 0.9 0.0 0.0 0.3 0.0 0.0 0.1 0.5 0.7 0.0 0.2 1.3 0.5 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.2 0.1 0.4 0.0 11.0 0.0 0.3 0.0 0.0 0.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.5 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 0.7 0.1 0.4 0.8 0.4 0.9 0.2 0.8 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.9 0.3 0.1 0.0 0.0 0.0 253.9 0.2 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.3 0.0 TTC7B TTC7L1 ENSG00000165914 "Tetratricopeptide repeat domain 7B" Q86TV6 14 90524564-90816479 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 88.8;Excitatory neurons: 116.7;Inhibitory neurons: 132.8;Oligodendrocyte precursor cells: 69.9;Oligodendrocytes: 70.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 7 "basophil: 5.6;eosinophil: 8.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 8.0" "Cell line enhanced" "Detected in many" "HMC-1: 72.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA058363, HPA059577" Enhanced Supported "Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "HPA058363: AB_2683692, HPA059577: AB_2684069" "unprognostic (9.37e-2)" "unprognostic (4.20e-2)" "unprognostic (1.01e-2)" "unprognostic (2.41e-2)" "unprognostic (2.58e-1)" "unprognostic (2.67e-4)" "unprognostic (9.42e-2)" "unprognostic (2.17e-1)" "unprognostic (5.38e-2)" "unprognostic (7.60e-2)" "unprognostic (2.75e-3)" "unprognostic (2.87e-2)" "prognostic favorable (3.20e-6)" "unprognostic (2.74e-2)" "unprognostic (7.41e-2)" "unprognostic (4.48e-2)" "unprognostic (1.07e-2)" 23.7 11.6 42.9 9.1 43.4 10.2 18.1 47.1 57.2 20.1 0.7 37.9 5.0 24.2 6.1 15.5 18.0 9.2 33.2 51.0 18.7 16.9 17.6 18.5 4.1 35.7 32.2 15.8 24.7 15.7 18.2 18.4 38.7 16.1 4.4 14.4 12.8 13.9 60.9 9.3 11.0 17.6 14.6 15.4 22.4 4.2 45.2 3.5 9.5 27.9 2.7 25.4 13.1 39.6 19.4 17.2 20.0 14.8 18.2 21.5 65.5 15.5 13.2 20.2 21.7 4.5 5.1 0.2 23.6 17.4 23.9 0.4 13.1 10.8 19.6 35.3 14.1 43.6 8.9 4.1 18.3 1.0 72.8 16.1 7.1 10.9 13.2 18.5 29.4 16.9 24.7 35.3 19.7 20.5 0.5 17.2 11.4 1.1 14.8 37.8 33.0 6.6 6.6 14.4 30.5 20.9 15.4 6.3 33.3 12.7 9.0 13.3 33.7 20.6 16.1 15.2 25.4 12.0 6.3 0.2 29.6 4.1 20.6 5.6 0.2 8.0 0.1 0.5 0.2 0.1 0.1 0.1 0.3 0.1 0.1 0.1 1.0 0.3 0.1 0.5 0.9 0.5 42.9 43.4 47.1 57.2 51.0 18.7 35.7 32.2 38.7 14.6 45.2 39.6 13.1 3.2 1.1 88.8 0.5 2.8 2.1 1.1 0.6 13.4 2.7 2.8 21.6 2.8 0.4 5.5 16.7 13.1 0.6 0.1 1.9 2.3 5.9 1.3 5.2 7.9 1.2 2.5 116.7 2.4 7.4 7.3 0.5 2.0 7.6 20.0 10.8 9.9 8.1 30.3 132.8 0.1 4.1 5.6 4.3 3.2 6.8 7.2 12.4 36.5 2.7 6.0 0.0 69.9 70.7 0.8 0.1 7.2 0.4 3.0 0.3 4.0 5.5 17.8 26.3 9.9 9.2 1.7 1.6 0.7 2.0 30.1 1.1 2.1 0.0 1.2 TWF2 "A6r, A6RP, PTK9L" ENSG00000247596 "Twinfilin actin binding protein 2" Q6IBS0 3 52228612-52246788 "Plasma proteins, Predicted intracellular proteins" "Cilium biogenesis/degradation" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 183.4" "Cell type enhanced" "Detected in many" "Hofbauer cells: 205.0;monocytes: 202.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA053874 Uncertain Uncertain "Plasma membrane" NA NA 5900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "HPA053874: AB_2682287" "unprognostic (4.24e-2)" "unprognostic (8.61e-2)" "unprognostic (2.18e-1)" "unprognostic (2.62e-2)" "unprognostic (2.70e-2)" "unprognostic (3.51e-2)" "unprognostic (5.46e-3)" "unprognostic (2.76e-1)" "unprognostic (6.56e-2)" "unprognostic (1.97e-1)" "unprognostic (2.58e-2)" "unprognostic (5.07e-2)" "unprognostic (4.31e-3)" "unprognostic (4.40e-1)" "unprognostic (1.03e-1)" "unprognostic (1.09e-1)" "unprognostic (7.07e-2)" 50.3 32.0 16.6 28.1 16.4 28.3 39.0 12.9 26.5 35.7 13.2 32.4 21.8 35.4 0.6 44.5 27.9 17.2 94.8 17.3 15.4 31.2 29.3 34.9 33.3 15.5 13.7 29.5 17.3 6.8 18.3 15.8 16.0 29.1 4.8 0.9 36.7 18.7 183.4 32.4 33.6 14.1 15.4 54.8 24.5 14.2 14.7 21.3 23.8 4.3 15.1 36.2 36.4 18.0 24.9 59.8 10.7 28.6 29.1 47.5 35.7 56.0 55.9 49.1 43.4 32.3 51.6 89.9 36.5 27.1 39.2 37.5 11.9 60.0 4.2 52.4 34.0 89.6 38.0 78.9 49.1 54.3 139.6 46.4 28.8 50.4 12.8 21.9 82.9 50.1 21.0 36.0 20.7 21.7 65.0 117.1 30.4 15.2 171.9 27.0 22.0 92.0 22.3 38.4 13.6 59.7 19.7 74.7 109.2 4.2 19.3 40.5 105.9 55.1 68.4 50.4 47.4 37.4 35.9 45.6 125.9 143.8 73.7 97.5 167.8 143.4 107.7 169.1 95.0 109.1 112.4 114.6 159.7 83.1 86.5 108.9 242.0 93.7 181.6 150.6 141.9 149.6 16.6 16.4 12.9 26.5 17.3 15.4 15.5 13.7 16.0 15.4 14.7 18.0 44.3 6.4 7.8 2.0 50.7 17.2 29.5 59.2 12.5 14.0 29.9 28.2 28.8 27.1 23.7 12.9 0.0 42.4 77.0 64.4 37.2 86.8 3.1 34.2 27.5 35.9 22.1 17.7 7.5 100.8 84.3 34.0 18.8 86.3 40.6 28.4 31.1 13.3 205.0 6.7 4.2 20.2 30.5 108.8 56.7 2.7 35.1 111.8 33.8 3.7 202.4 14.9 97.9 3.5 3.5 103.2 55.7 33.8 25.2 20.3 65.5 25.4 12.2 5.1 52.6 16.1 38.6 1.7 25.1 27.2 15.3 22.6 64.4 53.7 23.9 31.3 TYROBP "DAP12, KARAP, PLO-SL, PLOSL" ENSG00000011600 "Transmembrane immune signaling adaptor TYROBP" O43914 19 35904401-35908295 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" Immunity "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 596.8;lymphoid tissue: 423.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 3777.1;Kupffer cells: 3698.1;Langerhans cells: 1990.8;Macrophages: 2837.1;monocytes: 3371.2;NK-cells: 1772.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 6415.4" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "HMC-1: 678.1;THP-1: 390.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009493, HPA041899" Enhanced Supported "Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "CAB009493: AB_638987, HPA041899: AB_10795266" "unprognostic (7.09e-2)" "unprognostic (8.38e-3)" "unprognostic (7.87e-2)" "unprognostic (4.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.39e-1)" "unprognostic (5.27e-2)" "unprognostic (8.04e-2)" "unprognostic (2.07e-2)" "unprognostic (2.47e-1)" "unprognostic (2.91e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (1.05e-4)" "unprognostic (4.47e-2)" "unprognostic (1.72e-2)" "unprognostic (4.27e-2)" "unprognostic (4.39e-2)" 126.3 76.1 55.8 234.3 54.3 596.8 59.1 58.6 116.8 44.3 61.4 62.0 70.6 25.9 15.0 28.1 43.7 105.0 39.7 53.0 66.4 34.4 85.5 261.5 161.0 81.7 64.0 18.3 24.7 22.0 27.0 124.7 74.8 31.7 49.8 3.9 38.3 26.7 10.6 21.5 78.8 68.0 74.1 423.3 43.1 15.0 74.0 52.5 21.9 31.6 36.6 131.7 21.5 114.4 0.3 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 56.7 0.0 0.0 0.5 33.2 678.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 1.0 0.0 0.0 0.0 49.1 0.3 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.3 0.5 0.0 0.0 0.2 0.9 0.0 390.6 0.0 0.0 0.3 0.8 0.1 0.4 0.1 1.0 0.1 10.8 0.1 974.2 4983.5 2573.9 468.0 3367.8 246.5 22.4 9.5 64.2 1912.0 8.4 11.7 51.2 6415.4 1664.1 3413.8 1653.1 9.5 5260.2 55.8 54.3 58.6 116.8 53.0 66.4 81.7 64.0 74.8 74.1 74.0 114.4 24.5 57.7 168.4 0.0 50.9 55.2 2.0 0.0 1.2 0.1 11.5 43.3 6.8 34.3 43.4 20.2 0.0 19.8 987.6 1.7 1.9 2.1 3.9 1.3 1.4 47.1 0.0 87.8 0.1 5.8 28.0 24.9 5.6 1.5 753.7 0.3 73.2 25.0 3777.1 0.0 0.1 0.2 0.0 3698.1 1990.8 11.6 9.3 2837.1 56.9 18.7 3371.2 0.6 1772.4 0.0 0.1 1.3 2.3 1.2 19.4 1.5 0.5 8.9 20.5 1.8 78.9 5.3 10.0 0.9 3.0 4.9 44.6 38.9 236.5 0.1 0.5 1.8 VANGL1 STB2 ENSG00000173218 "VANGL planar cell polarity protein 1" Q8TAA9 1 115641970-115698224 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 39.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "NK-cell: 6.2" "Group enriched" "Detected in many" 7 "dendritic cells: 2.3;NK-cells: 6.2;T-cells: 3.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025235, CAB076375" Approved Approved "Plasma membrane" NA Yes "Cluster 48: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "CAB076375: AB_2665604, HPA025235: AB_1858718" "unprognostic (1.04e-2)" "unprognostic (2.04e-2)" "prognostic favorable (7.53e-4)" "unprognostic (9.94e-2)" "unprognostic (1.71e-2)" "unprognostic (5.18e-2)" "unprognostic (2.18e-3)" "unprognostic (5.11e-3)" "unprognostic (2.11e-1)" "unprognostic (6.43e-3)" "prognostic unfavorable (7.89e-4)" "unprognostic (1.88e-2)" "unprognostic (1.74e-2)" "unprognostic (7.71e-3)" "unprognostic (1.21e-1)" "unprognostic (4.50e-3)" "unprognostic (9.06e-3)" 4.9 3.9 2.1 3.8 1.2 2.5 3.2 0.8 1.1 9.1 3.0 6.8 3.8 5.5 4.9 10.4 12.0 3.8 5.4 1.3 1.3 5.3 3.0 4.1 2.1 1.2 3.0 4.4 5.0 5.2 0.5 3.6 1.7 4.4 6.4 1.6 6.4 4.5 0.9 6.8 3.9 7.3 1.2 2.2 5.5 5.0 6.5 7.3 7.6 2.4 2.5 6.4 4.4 1.0 49.6 20.7 6.6 8.9 24.1 21.5 13.1 18.8 13.5 24.1 19.1 12.0 24.1 0.0 31.5 21.9 22.7 60.9 11.2 33.3 15.8 57.9 13.7 27.4 18.4 9.8 8.8 8.2 11.4 11.4 23.1 17.2 18.2 12.8 24.1 45.9 16.8 14.8 24.5 65.7 41.0 3.4 16.7 28.8 19.5 0.1 19.1 14.3 11.0 32.8 5.9 8.0 33.9 22.2 15.4 12.4 11.3 8.8 26.2 16.5 25.7 36.3 34.6 2.1 2.3 0.2 22.3 14.3 41.1 0.0 0.5 0.0 1.9 0.3 0.5 0.2 1.2 1.9 2.3 0.0 0.4 2.0 0.0 6.2 0.5 2.0 3.0 1.0 2.1 1.2 0.8 1.1 1.3 1.3 1.2 3.0 1.7 1.2 6.5 1.0 9.2 3.2 3.2 5.5 0.5 7.4 7.4 16.8 11.4 5.2 4.6 4.6 7.9 2.8 9.6 9.2 39.6 5.0 3.4 11.2 0.0 15.7 6.1 25.1 7.7 10.5 6.7 13.2 0.9 13.8 7.3 10.1 8.2 17.0 0.0 5.1 28.9 2.5 4.3 0.0 0.7 8.6 10.2 1.9 1.4 3.0 5.9 2.9 0.0 4.7 11.1 4.7 9.2 2.0 0.1 20.8 6.1 8.2 1.8 8.3 2.6 5.6 12.8 0.9 6.6 4.3 8.5 5.5 7.0 20.0 6.5 0.4 3.1 3.2 10.3 6.5 VIL1 "D2S1471, VIL" ENSG00000127831 "Villin 1" P09327 2 218419121-218453295 "Cancer-related genes, Disease related genes, Plasma proteins, Predicted intracellular proteins" Apoptosis "Actin capping, Actin-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 14 "intestine: 436.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 243.8;Enteroendocrine cells: 113.6;Intestinal goblet cells: 143.6;Paneth cells: 216.2;Proximal enterocytes: 558.5;Undifferentiated cells: 161.8" "Group enriched" "Detected in many" 4 "colorectal cancer: 56.4;stomach cancer: 23.5" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 4 "neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.3" "Group enriched" "Detected in some" 97 "CACO-2: 762.5;Hep G2: 365.3;OE19: 321.9" "Low region specificity" "Detected in single" "Not detected" "Not detected" "CAB002452, HPA006884, HPA006885" Enhanced Enhanced "Plasma membrane" NA NA 6800 "Cluster 9: Neutrophils - Innate immune response" "Cluster 9: Intestine - Unknown function" "Cluster 39: CACO-2 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" "CAB002452: AB_564052, HPA006884: AB_1080566, HPA006885: AB_1080564" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (1.61e-2)" "unprognostic (1.09e-1)" "unprognostic (1.83e-1)" "unprognostic (3.36e-1)" "unprognostic (3.03e-1)" "unprognostic (5.90e-2)" "unprognostic (2.44e-2)" "unprognostic (7.06e-2)" "unprognostic (4.14e-1)" "unprognostic (1.03e-1)" "unprognostic (2.25e-3)" "unprognostic (3.90e-1)" "unprognostic (2.58e-1)" "unprognostic (4.79e-2)" "unprognostic (4.65e-2)" 0.6 1.1 0.0 10.3 0.1 0.3 0.8 0.3 0.2 0.7 0.0 175.9 395.0 0.5 0.0 0.9 0.7 28.1 1.0 0.0 0.0 25.9 31.4 0.7 0.3 0.0 0.0 1.1 29.4 0.0 1.4 0.3 0.0 1.0 184.0 0.0 0.6 0.4 0.4 1.1 436.3 8.1 0.0 1.2 6.9 2.0 0.0 0.0 0.6 0.0 0.0 0.8 0.9 0.1 0.0 1.5 0.0 0.1 0.0 0.1 1.0 0.0 0.0 0.0 0.0 762.5 0.5 0.1 5.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.4 0.0 0.3 365.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.1 0.0 0.1 0.0 1.7 0.8 321.9 0.0 0.0 0.0 1.4 0.0 0.2 0.3 0.7 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.1 0.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.2 0.0 4.0 0.0 0.1 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 1.3 0.8 0.4 0.1 0.0 1.8 0.3 0.6 0.5 24.3 0.1 0.0 2.1 0.3 0.8 243.8 3.9 12.3 1.9 1.3 0.9 0.4 113.6 3.2 0.7 42.9 0.2 0.8 6.6 1.6 8.9 0.3 0.7 32.6 0.1 1.7 0.5 143.6 0.0 2.2 1.5 0.5 0.0 5.1 0.0 0.0 0.2 0.5 0.0 0.0 0.3 10.9 216.2 0.0 0.3 0.9 558.5 35.1 0.0 1.2 0.0 1.7 0.7 0.8 0.8 0.6 0.9 0.3 1.5 0.0 161.8 0.3 ZBTB8OS ARCH ENSG00000176261 "Zinc finger and BTB domain containing 8 opposite strand" Q8IWT0 1 32600172-32650903 "Predicted intracellular proteins" "tRNA processing" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA046315 Approved Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" "HPA046315: AB_2679623" "unprognostic (3.41e-2)" "unprognostic (1.39e-2)" "unprognostic (1.08e-1)" "unprognostic (9.08e-2)" "unprognostic (1.82e-1)" "unprognostic (8.14e-2)" "prognostic unfavorable (4.25e-4)" "unprognostic (9.63e-2)" "prognostic unfavorable (8.56e-4)" "unprognostic (5.18e-2)" "unprognostic (3.84e-1)" "unprognostic (1.40e-1)" "prognostic unfavorable (7.11e-8)" "unprognostic (1.94e-2)" "unprognostic (2.79e-1)" "unprognostic (1.68e-1)" "unprognostic (1.42e-1)" 21.5 25.5 21.1 28.7 21.0 21.5 20.6 23.7 34.4 17.1 20.4 33.8 32.2 16.3 35.6 27.2 18.3 14.7 32.4 20.9 22.5 28.2 34.5 20.3 36.9 20.9 20.8 12.4 27.4 21.5 27.7 14.9 21.1 21.6 33.3 27.6 22.8 15.9 43.6 17.0 29.1 20.2 20.3 27.1 28.5 16.5 21.9 16.9 18.3 35.5 43.8 21.4 18.2 22.2 56.1 31.8 27.9 47.2 47.7 43.3 38.1 62.1 62.3 48.5 49.0 75.5 60.9 62.0 55.9 45.6 53.5 41.1 48.7 48.5 64.4 83.2 44.8 50.5 67.4 127.0 39.2 73.2 44.9 43.4 52.3 42.7 51.2 30.3 53.6 74.6 50.8 81.6 62.9 44.3 56.2 42.4 86.1 86.5 48.7 44.9 59.8 60.7 58.7 65.7 55.9 43.0 50.1 49.9 83.3 74.8 34.2 59.8 38.4 67.2 40.8 55.0 78.9 123.1 130.8 177.0 48.1 89.6 68.1 37.5 57.7 71.5 46.3 71.0 44.8 73.0 50.5 56.0 41.6 54.0 41.9 45.1 66.3 48.0 78.0 53.6 86.1 37.8 21.1 21.0 23.7 34.4 20.9 22.5 20.9 20.8 21.1 20.3 21.9 22.2 39.4 22.4 53.7 32.0 56.3 17.2 31.2 69.5 18.2 46.9 28.5 34.7 69.3 30.0 53.3 38.6 43.8 49.3 54.5 68.8 90.1 60.5 38.1 42.5 38.1 34.4 37.7 46.1 58.3 52.7 61.8 35.9 35.2 45.3 44.2 24.0 33.2 82.5 72.3 16.8 60.5 53.2 71.2 61.9 19.8 30.5 36.7 47.4 51.6 21.5 82.2 35.7 75.2 35.7 46.8 68.4 71.6 46.3 79.9 32.8 115.9 139.4 42.0 56.5 32.9 27.3 51.7 52.9 30.0 28.1 15.6 65.1 50.3 31.2 49.7 37.8 ZDHHC2 "DHHC2, ZNF372" ENSG00000104219 "Zinc finger DHHC-type palmitoyltransferase 2" Q9UIJ5 8 17156482-17224799 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 77.8" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023331, HPA023334" Uncertain Approved "Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 77: Retina - Visual perception" "Cluster 2: Karpas-707 - Immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "HPA023331: AB_2671165, HPA023334: " "unprognostic (8.92e-2)" "unprognostic (4.23e-1)" "unprognostic (1.80e-2)" "unprognostic (2.53e-1)" "unprognostic (6.89e-2)" "unprognostic (2.25e-1)" "unprognostic (6.12e-2)" "unprognostic (1.78e-2)" "unprognostic (1.04e-1)" "unprognostic (2.37e-2)" "unprognostic (2.16e-1)" "unprognostic (1.58e-1)" "prognostic favorable (3.24e-4)" "unprognostic (5.00e-2)" "unprognostic (3.87e-1)" "unprognostic (2.87e-2)" "unprognostic (5.10e-2)" 10.3 24.4 10.3 11.0 8.9 31.7 7.5 43.9 14.8 13.4 13.5 15.3 10.5 7.6 11.8 3.9 13.8 7.0 9.7 8.0 22.4 26.4 6.5 14.3 9.3 17.7 13.6 11.8 30.7 28.9 9.5 6.9 16.6 11.7 11.2 77.8 19.6 12.9 17.9 1.8 10.3 9.5 13.5 10.7 16.3 16.6 26.3 12.7 33.5 37.2 11.7 19.7 4.4 22.0 2.3 12.4 23.7 4.9 20.3 36.0 13.8 41.5 49.9 23.0 27.2 3.9 34.3 26.1 15.9 36.2 57.9 1.5 32.2 20.5 42.5 16.8 16.2 23.2 16.8 5.0 20.3 24.7 2.6 15.3 3.2 28.8 26.1 52.7 38.4 29.8 2.7 66.5 28.1 0.6 18.3 15.2 15.0 18.8 19.1 17.9 23.7 9.5 41.8 26.7 12.7 8.3 17.8 0.0 3.8 34.9 1.0 10.9 32.0 11.6 35.2 26.0 41.7 13.2 53.7 30.1 32.1 22.2 5.3 1.6 1.2 2.6 1.9 1.3 3.3 2.5 2.4 2.3 1.1 2.1 2.1 2.3 0.9 2.2 0.8 2.3 1.3 0.7 10.3 8.9 43.9 14.8 8.0 22.4 17.7 13.6 16.6 13.5 26.3 22.0 20.9 44.8 25.4 34.0 18.8 3.1 15.3 4.1 1.8 54.4 21.1 8.0 15.2 15.7 10.5 51.5 77.2 0.5 27.1 8.7 21.5 22.2 8.3 19.3 6.8 11.6 19.7 22.7 49.8 33.4 1.2 10.4 9.7 25.4 8.2 10.9 10.0 8.0 12.6 11.8 20.1 16.2 6.1 28.6 16.1 11.7 5.0 22.2 23.2 37.5 12.9 40.6 8.2 26.7 61.3 37.0 10.7 3.0 14.0 31.3 6.1 26.1 7.7 90.2 13.1 9.1 7.5 6.6 3.9 3.3 2.7 0.4 17.0 8.7 17.0 36.5 ZDHHC22 C14orf59 ENSG00000177108 "Zinc finger DHHC-type palmitoyltransferase 22" Q8N966 14 77131270-77142734 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "brain: 51.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.3;Excitatory neurons: 8.8;Inhibitory neurons: 13.4;Late spermatids: 5.0;Oligodendrocyte precursor cells: 24.6" "Cancer enriched" "Detected in single" 40 "glioma: 7.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "AF22: 3.6;NTERA-2: 3.8;RH-30: 6.4;SCLC-21H: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049471, HPA072213" Enhanced "Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" "HPA049471: AB_2732553, HPA072213: AB_2686496" "unprognostic (1.02e-1)" "unprognostic (3.42e-1)" "unprognostic (1.22e-4)" "unprognostic (1.66e-1)" "unprognostic (8.86e-2)" "unprognostic (2.68e-1)" "unprognostic (3.41e-1)" "unprognostic (1.87e-1)" "unprognostic (6.94e-4)" "unprognostic (3.05e-1)" "unprognostic (6.30e-2)" "unprognostic (1.16e-1)" "unprognostic (4.02e-1)" "unprognostic (1.95e-1)" "unprognostic (4.79e-1)" 0.0 0.2 14.9 0.0 15.3 0.0 0.0 25.9 33.8 0.1 0.0 0.7 0.0 0.0 0.2 0.1 0.0 0.0 0.0 21.2 12.8 0.0 0.0 0.0 0.0 1.2 22.7 0.0 0.0 0.0 4.7 0.0 1.0 0.0 0.1 7.2 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.2 0.5 51.3 0.0 0.1 0.4 0.0 0.1 0.0 13.9 0.0 0.0 3.6 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 3.8 0.0 0.5 0.0 6.4 0.0 0.0 0.0 7.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.9 15.3 25.9 33.8 21.2 12.8 1.2 22.7 1.0 0.0 51.3 13.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.3 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.3 0.0 0.0 8.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 24.6 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ZNF227 ENSG00000131115 "Zinc finger protein 227" Q86WZ6 19 44207547-44237268 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 30.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA030573 Uncertain Approved "Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "HPA030573: AB_10610702" "unprognostic (3.01e-2)" "unprognostic (1.79e-2)" "unprognostic (7.14e-2)" "unprognostic (2.77e-2)" "unprognostic (4.74e-2)" "unprognostic (1.66e-2)" "unprognostic (8.05e-2)" "unprognostic (7.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (5.68e-3)" "unprognostic (1.94e-1)" "unprognostic (4.88e-2)" "unprognostic (1.27e-1)" "unprognostic (2.21e-2)" "unprognostic (9.91e-2)" "prognostic favorable (2.64e-4)" 6.3 6.9 9.5 5.9 10.3 5.0 8.3 14.0 10.7 7.8 8.8 6.9 5.4 8.0 7.6 6.6 8.0 5.9 5.7 9.2 10.5 6.9 7.4 6.1 10.3 9.7 10.1 11.0 6.6 10.4 8.0 7.7 9.9 8.5 5.8 8.7 5.6 6.9 6.4 6.5 5.8 6.8 9.6 9.5 8.6 7.4 10.1 17.2 8.3 6.4 11.2 7.1 6.5 13.2 9.6 13.4 15.8 19.7 12.6 10.9 7.4 9.2 13.1 8.7 17.0 6.6 7.3 16.8 13.9 8.6 10.4 5.5 18.2 9.7 11.7 21.9 22.8 29.3 14.7 8.2 9.0 25.8 12.4 9.9 10.6 8.6 16.0 14.5 13.1 19.2 2.9 0.4 9.4 5.1 24.3 6.8 25.3 9.8 7.0 14.4 15.9 14.4 9.0 17.2 26.7 27.3 20.6 9.2 7.2 15.2 7.7 13.7 11.3 9.6 15.8 7.4 11.8 37.6 54.5 36.1 6.3 10.6 13.1 17.3 4.8 9.9 10.8 3.5 11.8 12.0 10.2 10.6 5.9 12.2 13.3 11.2 4.2 11.9 3.5 6.2 13.5 5.7 9.5 10.3 14.0 10.7 9.2 10.5 9.7 10.1 9.9 9.6 10.1 13.2 8.0 0.0 1.5 13.7 8.1 3.1 3.8 4.8 3.4 6.0 5.4 4.6 7.0 1.5 6.4 5.5 2.1 5.6 6.3 3.3 3.9 4.2 22.6 4.0 4.6 8.4 2.4 7.8 10.5 4.0 4.5 4.4 3.6 3.7 1.3 8.7 8.9 3.9 4.4 8.4 10.3 4.7 2.0 5.7 3.7 30.0 5.6 3.9 1.8 9.4 5.2 6.3 11.3 17.1 16.8 6.1 3.3 5.7 4.0 6.0 4.2 3.3 4.1 5.4 6.6 5.9 5.5 4.4 8.7 3.3 3.8 2.2 6.9 8.6 3.3 2.9 ZNF706 HSPC038 ENSG00000120963 "Zinc finger protein 706" Q9Y5V0 8 101177878-101206193 "Predicted intracellular proteins" "Translation regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1090.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042793 Approved "Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 50: Non-specific - Ribosome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "HPA042793: AB_10795710" "unprognostic (2.05e-2)" "unprognostic (3.29e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (3.12e-5)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "unprognostic (2.48e-3)" "unprognostic (5.22e-2)" "unprognostic (3.19e-2)" "unprognostic (1.21e-2)" "unprognostic (1.35e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (5.90e-11)" "unprognostic (9.65e-2)" "unprognostic (1.59e-1)" "unprognostic (3.57e-1)" "unprognostic (2.17e-2)" 99.5 83.4 85.6 57.3 85.3 76.9 92.6 89.1 114.7 86.7 54.6 93.3 93.3 71.5 90.4 147.2 69.0 69.2 86.0 87.2 72.9 95.9 96.0 81.9 95.5 69.0 72.8 70.2 269.9 69.8 93.9 55.3 69.6 70.9 87.2 46.9 99.1 49.1 110.7 180.0 100.0 50.7 69.7 100.5 92.7 118.1 70.0 67.2 82.3 86.1 102.5 75.1 101.1 83.1 203.0 113.9 196.0 62.7 69.0 78.0 124.8 82.4 105.5 83.5 89.0 81.8 121.5 121.9 139.4 99.1 170.4 108.4 113.3 111.0 95.8 90.5 98.0 122.1 69.5 159.2 90.7 92.2 114.1 69.1 170.9 78.9 170.7 115.1 144.0 121.4 134.8 230.6 75.0 142.6 194.5 252.2 59.7 408.6 278.8 80.8 65.3 251.1 112.7 103.2 129.4 57.6 57.6 95.0 375.9 166.3 99.3 96.5 96.3 45.6 93.9 121.9 87.0 194.1 202.6 197.0 123.5 199.2 215.8 255.1 280.0 162.6 138.0 463.2 143.4 400.0 191.5 178.0 264.1 344.1 214.7 206.3 38.7 130.9 492.1 532.8 302.8 268.7 85.6 85.3 89.1 114.7 87.2 72.9 69.0 72.8 69.6 69.7 70.0 83.1 131.4 60.9 41.0 29.0 188.6 459.7 242.3 252.7 149.7 59.3 159.3 182.6 79.8 137.2 138.1 79.1 18.8 190.6 175.0 288.4 180.0 264.5 439.7 125.5 70.1 137.7 265.1 107.1 31.5 259.8 339.0 131.4 106.5 114.9 122.2 85.1 99.2 123.4 265.3 85.8 21.1 275.3 231.9 162.3 186.4 1090.7 86.9 214.8 206.3 16.9 298.4 131.3 114.4 14.6 57.6 401.5 265.4 86.9 329.4 326.5 339.2 195.1 110.8 55.9 105.2 111.6 169.8 84.3 82.7 224.8 518.0 193.3 112.7 72.7 153.5 311.7