Gene "Gene synonym" Ensembl "Gene description" Uniprot Chromosome Position "Protein class" "Biological process" "Molecular function" "Disease involvement" Evidence "HPA evidence" "UniProt evidence" "NeXtProt evidence" "RNA tissue specificity" "RNA tissue distribution" "RNA tissue specificity score" "RNA tissue specific nTPM" "RNA single cell type specificity" "RNA single cell type distribution" "RNA single cell type specificity score" "RNA single cell type specific nTPM" "RNA cancer specificity" "RNA cancer distribution" "RNA cancer specificity score" "RNA cancer specific FPKM" "RNA brain regional specificity" "RNA brain regional distribution" "RNA brain regional specificity score" "RNA brain regional specific nTPM" "RNA blood cell specificity" "RNA blood cell distribution" "RNA blood cell specificity score" "RNA blood cell specific nTPM" "RNA blood lineage specificity" "RNA blood lineage distribution" "RNA blood lineage specificity score" "RNA blood lineage specific nTPM" "RNA cell line specificity" "RNA cell line distribution" "RNA cell line specificity score" "RNA cell line specific nTPM" "RNA mouse brain regional specificity" "RNA mouse brain regional distribution" "RNA mouse brain regional specificity score" "RNA mouse brain regional specific nTPM" "RNA pig brain regional specificity" "RNA pig brain regional distribution" "RNA pig brain regional specificity score" "RNA pig brain regional specific nTPM" Antibody "Reliability (IH)" "Reliability (Mouse Brain)" "Reliability (IF)" "Subcellular location" "Secretome location" "CCD Protein" "CCD Transcript" "Blood concentration - Conc. blood IM [pg/L]" "Blood concentration - Conc. blood MS [pg/L]" "Blood expression cluster" "Tissue expression cluster" "Cell line expression cluster" "Single cell expression cluster" "Subcellular main location" "Subcellular additional location" "Antibody RRID" "Pathology prognostics - Breast cancer" "Pathology prognostics - Cervical cancer" "Pathology prognostics - Colorectal cancer" "Pathology prognostics - Endometrial cancer" "Pathology prognostics - Glioma" "Pathology prognostics - Head and neck cancer" "Pathology prognostics - Liver cancer" "Pathology prognostics - Lung cancer" "Pathology prognostics - Melanoma" "Pathology prognostics - Ovarian cancer" "Pathology prognostics - Pancreatic cancer" "Pathology prognostics - Prostate cancer" "Pathology prognostics - Renal cancer" "Pathology prognostics - Stomach cancer" "Pathology prognostics - Testis cancer" "Pathology prognostics - Thyroid cancer" "Pathology prognostics - Urothelial cancer" "Tissue RNA - adipose tissue [nTPM]" "Tissue RNA - adrenal gland [nTPM]" "Tissue RNA - amygdala [nTPM]" "Tissue RNA - appendix [nTPM]" "Tissue RNA - basal ganglia [nTPM]" "Tissue RNA - bone marrow [nTPM]" "Tissue RNA - breast [nTPM]" "Tissue RNA - cerebellum [nTPM]" "Tissue RNA - cerebral cortex [nTPM]" "Tissue RNA - cervix [nTPM]" "Tissue RNA - choroid plexus [nTPM]" "Tissue RNA - colon [nTPM]" "Tissue RNA - duodenum [nTPM]" "Tissue RNA - endometrium 1 [nTPM]" "Tissue RNA - epididymis [nTPM]" "Tissue RNA - esophagus [nTPM]" "Tissue RNA - fallopian tube [nTPM]" "Tissue RNA - gallbladder [nTPM]" "Tissue RNA - heart muscle [nTPM]" "Tissue RNA - hippocampal formation [nTPM]" "Tissue RNA - hypothalamus [nTPM]" "Tissue RNA - kidney [nTPM]" "Tissue RNA - liver [nTPM]" "Tissue RNA - lung [nTPM]" "Tissue RNA - lymph node [nTPM]" "Tissue RNA - medulla oblongata [nTPM]" "Tissue RNA - midbrain [nTPM]" "Tissue RNA - ovary [nTPM]" "Tissue RNA - pancreas [nTPM]" "Tissue RNA - parathyroid gland [nTPM]" "Tissue RNA - pituitary gland [nTPM]" "Tissue RNA - placenta [nTPM]" "Tissue RNA - pons [nTPM]" "Tissue RNA - prostate [nTPM]" "Tissue RNA - rectum [nTPM]" "Tissue RNA - retina [nTPM]" "Tissue RNA - salivary gland [nTPM]" "Tissue RNA - seminal vesicle [nTPM]" "Tissue RNA - skeletal muscle [nTPM]" "Tissue RNA - skin 1 [nTPM]" "Tissue RNA - small intestine [nTPM]" "Tissue RNA - smooth muscle [nTPM]" "Tissue RNA - spinal cord [nTPM]" "Tissue RNA - spleen [nTPM]" "Tissue RNA - stomach 1 [nTPM]" "Tissue RNA - testis [nTPM]" "Tissue RNA - thalamus [nTPM]" "Tissue RNA - thymus [nTPM]" "Tissue RNA - thyroid gland [nTPM]" "Tissue RNA - tongue [nTPM]" "Tissue RNA - tonsil [nTPM]" "Tissue RNA - urinary bladder [nTPM]" "Tissue RNA - vagina [nTPM]" "Tissue RNA - white matter [nTPM]" "Cell RNA - A-431 [nTPM]" "Cell RNA - A549 [nTPM]" "Cell RNA - AF22 [nTPM]" "Cell RNA - AN3-CA [nTPM]" "Cell RNA - ASC diff [nTPM]" "Cell RNA - ASC TERT1 [nTPM]" "Cell RNA - BEWO [nTPM]" "Cell RNA - BJ [nTPM]" "Cell RNA - BJ hTERT+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ [nTPM]" "Cell RNA - BJ hTERT+ SV40 Large T+ RasG12V [nTPM]" "Cell RNA - CACO-2 [nTPM]" "Cell RNA - CAPAN-2 [nTPM]" "Cell RNA - Daudi [nTPM]" "Cell RNA - EFO-21 [nTPM]" "Cell RNA - fHDF/TERT166 [nTPM]" "Cell RNA - GAMG [nTPM]" "Cell RNA - HaCaT [nTPM]" "Cell RNA - HAP1 [nTPM]" "Cell RNA - HBEC3-KT [nTPM]" "Cell RNA - HBF TERT88 [nTPM]" "Cell RNA - HDLM-2 [nTPM]" "Cell RNA - HEK 293 [nTPM]" "Cell RNA - HEL [nTPM]" "Cell RNA - HeLa [nTPM]" "Cell RNA - Hep G2 [nTPM]" "Cell RNA - HHSteC [nTPM]" "Cell RNA - HL-60 [nTPM]" "Cell RNA - HMC-1 [nTPM]" "Cell RNA - HSkMC [nTPM]" "Cell RNA - hTCEpi [nTPM]" "Cell RNA - hTEC/SVTERT24-B [nTPM]" "Cell RNA - hTERT-HME1 [nTPM]" "Cell RNA - hTERT-RPE1 [nTPM]" "Cell RNA - HUVEC TERT2 [nTPM]" "Cell RNA - JURKAT [nTPM]" "Cell RNA - K-562 [nTPM]" "Cell RNA - Karpas-707 [nTPM]" "Cell RNA - LHCN-M2 [nTPM]" "Cell RNA - MCF7 [nTPM]" "Cell RNA - MOLT-4 [nTPM]" "Cell RNA - NB-4 [nTPM]" "Cell RNA - NTERA-2 [nTPM]" "Cell RNA - OE19 [nTPM]" "Cell RNA - PC-3 [nTPM]" "Cell RNA - REH [nTPM]" "Cell RNA - RH-30 [nTPM]" "Cell RNA - RPMI-8226 [nTPM]" "Cell RNA - RPTEC TERT1 [nTPM]" "Cell RNA - RT4 [nTPM]" "Cell RNA - SCLC-21H [nTPM]" "Cell RNA - SH-SY5Y [nTPM]" "Cell RNA - SiHa [nTPM]" "Cell RNA - SK-BR-3 [nTPM]" "Cell RNA - SK-MEL-30 [nTPM]" "Cell RNA - SuSa [nTPM]" "Cell RNA - T-47d [nTPM]" "Cell RNA - THP-1 [nTPM]" "Cell RNA - TIME [nTPM]" "Cell RNA - U-138 MG [nTPM]" "Cell RNA - U-2 OS [nTPM]" "Cell RNA - U-2197 [nTPM]" "Cell RNA - U-251 MG [nTPM]" "Cell RNA - U-266/70 [nTPM]" "Cell RNA - U-266/84 [nTPM]" "Cell RNA - U-698 [nTPM]" "Cell RNA - U-87 MG [nTPM]" "Cell RNA - U-937 [nTPM]" "Cell RNA - WM-115 [nTPM]" "Blood RNA - basophil [nTPM]" "Blood RNA - classical monocyte [nTPM]" "Blood RNA - eosinophil [nTPM]" "Blood RNA - gdT-cell [nTPM]" "Blood RNA - intermediate monocyte [nTPM]" "Blood RNA - MAIT T-cell [nTPM]" "Blood RNA - memory B-cell [nTPM]" "Blood RNA - memory CD4 T-cell [nTPM]" "Blood RNA - memory CD8 T-cell [nTPM]" "Blood RNA - myeloid DC [nTPM]" "Blood RNA - naive B-cell [nTPM]" "Blood RNA - naive CD4 T-cell [nTPM]" "Blood RNA - naive CD8 T-cell [nTPM]" "Blood RNA - neutrophil [nTPM]" "Blood RNA - NK-cell [nTPM]" "Blood RNA - non-classical monocyte [nTPM]" "Blood RNA - plasmacytoid DC [nTPM]" "Blood RNA - T-reg [nTPM]" "Blood RNA - total PBMC [nTPM]" "Brain RNA - amygdala [nTPM]" "Brain RNA - basal ganglia [nTPM]" "Brain RNA - cerebellum [nTPM]" "Brain RNA - cerebral cortex [nTPM]" "Brain RNA - hippocampal formation [nTPM]" "Brain RNA - hypothalamus [nTPM]" "Brain RNA - medulla oblongata [nTPM]" "Brain RNA - midbrain [nTPM]" "Brain RNA - pons [nTPM]" "Brain RNA - spinal cord [nTPM]" "Brain RNA - thalamus [nTPM]" "Brain RNA - white matter [nTPM]" "Single Cell Type RNA - Adipocytes [nTPM]" "Single Cell Type RNA - Alveolar cells type 1 [nTPM]" "Single Cell Type RNA - Alveolar cells type 2 [nTPM]" "Single Cell Type RNA - Astrocytes [nTPM]" "Single Cell Type RNA - B-cells [nTPM]" "Single Cell Type RNA - Basal keratinocytes [nTPM]" "Single Cell Type RNA - Basal prostatic cells [nTPM]" "Single Cell Type RNA - Basal respiratory cells [nTPM]" "Single Cell Type RNA - Basal squamous epithelial cells [nTPM]" "Single Cell Type RNA - Bipolar cells [nTPM]" "Single Cell Type RNA - Breast glandular cells [nTPM]" "Single Cell Type RNA - Breast myoepithelial cells [nTPM]" "Single Cell Type RNA - Cardiomyocytes [nTPM]" "Single Cell Type RNA - Cholangiocytes [nTPM]" "Single Cell Type RNA - Club cells [nTPM]" "Single Cell Type RNA - Collecting duct cells [nTPM]" "Single Cell Type RNA - Cone photoreceptor cells [nTPM]" "Single Cell Type RNA - Cytotrophoblasts [nTPM]" "Single Cell Type RNA - dendritic cells [nTPM]" "Single Cell Type RNA - Distal enterocytes [nTPM]" "Single Cell Type RNA - Distal tubular cells [nTPM]" "Single Cell Type RNA - Ductal cells [nTPM]" "Single Cell Type RNA - Early spermatids [nTPM]" "Single Cell Type RNA - Endometrial ciliated cells [nTPM]" "Single Cell Type RNA - Endometrial stromal cells [nTPM]" "Single Cell Type RNA - Endothelial cells [nTPM]" "Single Cell Type RNA - Enteroendocrine cells [nTPM]" "Single Cell Type RNA - Erythroid cells [nTPM]" "Single Cell Type RNA - Excitatory neurons [nTPM]" "Single Cell Type RNA - Exocrine glandular cells [nTPM]" "Single Cell Type RNA - Extravillous trophoblasts [nTPM]" "Single Cell Type RNA - Fibroblasts [nTPM]" "Single Cell Type RNA - Gastric mucus-secreting cells [nTPM]" "Single Cell Type RNA - Glandular and luminal cells [nTPM]" "Single Cell Type RNA - granulocytes [nTPM]" "Single Cell Type RNA - Granulosa cells [nTPM]" "Single Cell Type RNA - Hepatic stellate cells [nTPM]" "Single Cell Type RNA - Hepatocytes [nTPM]" "Single Cell Type RNA - Hofbauer cells [nTPM]" "Single Cell Type RNA - Horizontal cells [nTPM]" "Single Cell Type RNA - Inhibitory neurons [nTPM]" "Single Cell Type RNA - Intestinal goblet cells [nTPM]" "Single Cell Type RNA - Ionocytes [nTPM]" "Single Cell Type RNA - Kupffer cells [nTPM]" "Single Cell Type RNA - Langerhans cells [nTPM]" "Single Cell Type RNA - Late spermatids [nTPM]" "Single Cell Type RNA - Leydig cells [nTPM]" "Single Cell Type RNA - Macrophages [nTPM]" "Single Cell Type RNA - Melanocytes [nTPM]" "Single Cell Type RNA - Microglial cells [nTPM]" "Single Cell Type RNA - monocytes [nTPM]" "Single Cell Type RNA - Muller glia cells [nTPM]" "Single Cell Type RNA - NK-cells [nTPM]" "Single Cell Type RNA - Oligodendrocyte precursor cells [nTPM]" "Single Cell Type RNA - Oligodendrocytes [nTPM]" "Single Cell Type RNA - Pancreatic endocrine cells [nTPM]" "Single Cell Type RNA - Paneth cells [nTPM]" "Single Cell Type RNA - Peritubular cells [nTPM]" "Single Cell Type RNA - Plasma cells [nTPM]" "Single Cell Type RNA - Prostatic glandular cells [nTPM]" "Single Cell Type RNA - Proximal enterocytes [nTPM]" "Single Cell Type RNA - Proximal tubular cells [nTPM]" "Single Cell Type RNA - Respiratory ciliated cells [nTPM]" "Single Cell Type RNA - Rod photoreceptor cells [nTPM]" "Single Cell Type RNA - Sertoli cells [nTPM]" "Single Cell Type RNA - Skeletal myocytes [nTPM]" "Single Cell Type RNA - Smooth muscle cells [nTPM]" "Single Cell Type RNA - Spermatocytes [nTPM]" "Single Cell Type RNA - Spermatogonia [nTPM]" "Single Cell Type RNA - Squamous epithelial cells [nTPM]" "Single Cell Type RNA - Suprabasal keratinocytes [nTPM]" "Single Cell Type RNA - Syncytiotrophoblasts [nTPM]" "Single Cell Type RNA - T-cells [nTPM]" "Single Cell Type RNA - Theca cells [nTPM]" "Single Cell Type RNA - Undifferentiated cells [nTPM]" "Single Cell Type RNA - Urothelial cells [nTPM]" AADAT "KAT2, KATII, KYAT2" ENSG00000109576 "Aminoadipate aminotransferase" Q8N5Z0 4 170060222-170091699 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Aminotransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 67.1" "Cell type enhanced" "Detected in many" "Astrocytes: 22.2;Extravillous trophoblasts: 71.3;Hepatocytes: 29.3;Spermatogonia: 27.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA037502 Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 85: Liver - Metabolism" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA037502: AB_10671759" "unprognostic (1.90e-1)" "unprognostic (1.82e-2)" "prognostic favorable (5.59e-4)" "unprognostic (4.21e-2)" "unprognostic (1.30e-1)" "unprognostic (1.06e-1)" "unprognostic (7.41e-2)" "unprognostic (1.03e-2)" "unprognostic (2.97e-2)" "unprognostic (3.38e-2)" "unprognostic (1.23e-2)" "unprognostic (3.55e-1)" "unprognostic (1.35e-1)" "unprognostic (1.23e-2)" "unprognostic (1.39e-1)" "unprognostic (7.28e-3)" "unprognostic (1.17e-2)" 3.3 2.8 6.2 1.9 6.8 0.3 4.7 3.8 9.8 9.8 11.3 6.2 1.6 10.5 5.9 2.6 6.3 3.9 2.7 6.5 6.7 6.8 67.1 4.9 0.7 5.8 5.6 4.7 5.6 6.0 6.1 1.9 6.5 14.4 5.0 11.8 1.7 5.3 4.0 1.4 2.3 7.3 4.8 1.7 3.6 8.2 6.1 1.5 7.5 2.4 0.8 6.4 5.7 8.7 3.5 8.5 25.0 0.0 4.9 18.9 9.0 8.7 4.2 4.9 5.0 8.4 1.0 0.1 1.4 9.8 6.5 2.9 11.3 4.1 3.4 0.0 9.7 0.0 10.0 14.0 3.9 0.1 3.8 7.7 2.5 4.0 5.1 13.5 4.7 11.4 1.5 0.1 19.0 8.9 4.3 0.1 19.0 9.6 7.6 0.0 7.8 0.0 4.4 15.3 20.1 23.5 7.0 1.7 8.5 8.0 0.1 1.7 3.2 12.5 13.4 14.3 13.9 0.1 0.0 0.1 12.5 0.0 15.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 6.8 3.8 9.8 6.5 6.7 5.8 5.6 6.5 4.8 6.1 8.7 0.9 0.0 5.9 22.2 0.3 0.9 2.8 0.9 6.2 6.0 3.9 1.0 1.2 1.5 2.1 0.0 2.1 2.8 0.0 0.7 0.0 1.6 0.5 3.7 7.4 0.7 6.7 0.0 15.4 2.2 71.3 3.2 3.1 6.0 0.0 6.2 0.7 29.3 1.6 0.0 13.6 2.8 0.0 0.3 0.9 1.4 1.2 0.4 1.8 5.6 0.0 2.7 0.0 17.6 14.0 1.1 1.6 2.2 0.0 4.0 0.2 8.4 8.5 9.1 6.6 3.9 4.2 14.5 27.1 3.0 0.4 5.6 0.3 3.3 3.1 1.8 ABCC1 "GS-X, MRP, MRP1" ENSG00000103222 "ATP binding cassette subfamily C member 1" P33527 16 15949138-16143257 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Transporters" Transport "Hydrolase, Translocase" "Cancer-related genes, Deafness, FDA approved drug targets, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 49.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "EFO-21: 79.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002380, HPA076011" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA002380: AB_1844432, HPA076011: " "unprognostic (9.97e-2)" "unprognostic (2.06e-1)" "unprognostic (2.05e-2)" "unprognostic (2.94e-1)" "unprognostic (4.89e-2)" "unprognostic (1.15e-1)" "prognostic unfavorable (5.42e-5)" "unprognostic (3.42e-1)" "unprognostic (3.31e-1)" "unprognostic (4.07e-2)" "unprognostic (9.78e-3)" "unprognostic (7.19e-2)" "prognostic unfavorable (1.55e-6)" "unprognostic (1.84e-1)" "unprognostic (1.15e-1)" "unprognostic (1.43e-2)" "unprognostic (1.80e-2)" 10.4 11.6 0.3 4.0 0.2 3.6 8.6 0.3 0.7 10.4 4.1 16.1 1.1 11.0 0.1 22.8 7.0 3.1 11.2 0.3 0.5 8.0 2.3 15.5 4.4 1.1 0.8 8.9 8.9 3.6 7.2 2.0 0.7 15.2 0.7 0.4 9.2 0.9 21.2 9.7 12.4 6.3 0.5 15.7 15.0 13.1 0.6 4.3 21.0 0.1 1.1 15.4 12.8 0.9 4.3 43.7 0.3 11.7 3.2 4.5 0.5 15.4 19.0 13.1 13.8 6.7 34.8 7.0 79.6 29.6 11.0 12.1 3.4 12.4 4.6 22.2 4.4 16.4 22.0 16.3 25.1 5.9 39.5 15.0 9.0 1.1 2.3 3.8 10.2 28.6 17.8 6.8 0.5 5.4 12.0 0.9 3.5 1.8 8.2 41.9 7.8 5.3 0.7 15.2 6.4 11.8 18.9 17.8 3.6 11.9 6.2 0.8 3.5 0.4 2.0 11.4 11.9 13.5 7.4 3.3 6.6 0.6 0.7 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.3 0.7 0.3 0.5 1.1 0.8 0.7 0.5 0.6 0.9 8.6 25.6 5.6 10.7 13.1 8.8 8.5 18.2 9.6 3.1 4.4 3.7 6.0 4.3 14.4 5.5 22.9 0.9 9.8 2.7 3.9 9.1 11.0 15.7 12.9 8.6 18.6 16.0 26.6 6.2 3.2 12.3 49.5 17.8 22.1 16.8 8.6 0.4 8.5 5.0 38.5 6.6 14.2 21.4 9.1 14.3 7.5 12.2 3.6 11.2 10.5 1.2 5.2 12.1 15.9 11.2 4.5 6.8 15.7 18.7 0.5 1.1 9.9 8.8 0.0 6.4 5.1 4.9 6.6 18.1 5.1 0.5 17.4 37.1 3.7 11.6 ABCC6 "ARA, EST349056, MLP1, MRP6, PXE, URG7" ENSG00000091262 "ATP binding cassette subfamily C member 6" O95255 16 16149565-16223522 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Sensory transduction, Transport, Vision" Translocase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "liver: 134.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 31.5;Distal tubular cells: 45.0;Hepatocytes: 77.9;Proximal enterocytes: 33.7;Proximal tubular cells: 151.1" "Group enriched" "Detected in many" 5 "liver cancer: 16.7;renal cancer: 5.0" "Low region specificity" "Detected in single" "Immune cell enriched" "Detected in single" 6 "classical monocyte: 3.4" "Lineage enriched" "Detected in single" 7 "monocytes: 3.4" "Cell line enriched" "Detected in some" 8 "Hep G2: 68.4" "Not detected" "Not detected" HPA038105 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA038105: AB_2675835" "unprognostic (1.32e-1)" "unprognostic (1.11e-1)" "unprognostic (5.98e-2)" "unprognostic (3.15e-2)" "unprognostic (1.59e-1)" "unprognostic (3.09e-1)" "prognostic favorable (3.82e-4)" "unprognostic (6.54e-3)" "unprognostic (3.64e-1)" "unprognostic (9.10e-2)" "unprognostic (1.30e-1)" "unprognostic (1.65e-1)" "unprognostic (1.12e-3)" "unprognostic (3.42e-1)" "unprognostic (2.00e-1)" "unprognostic (4.91e-2)" "unprognostic (1.41e-1)" 5.6 3.6 0.7 0.3 0.7 0.7 3.8 0.7 1.1 1.0 0.8 5.7 13.2 0.3 0.6 0.3 1.5 2.9 2.6 0.7 0.7 27.4 134.2 7.4 0.0 0.8 0.9 1.0 17.2 2.1 0.9 0.2 0.8 2.9 2.8 0.3 12.7 1.0 4.6 0.4 7.9 0.3 0.7 0.7 6.4 0.4 0.8 0.0 5.6 0.1 0.0 0.4 0.7 0.7 0.0 1.5 0.7 0.0 0.0 0.8 1.8 0.0 0.4 1.0 1.6 7.1 2.3 0.0 0.8 0.0 0.2 0.0 0.7 0.1 0.6 0.0 0.7 1.8 0.2 68.4 0.4 0.0 0.0 2.7 0.1 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.5 0.2 0.6 0.0 0.0 0.0 0.0 2.3 0.0 0.1 1.0 0.0 0.8 0.1 0.3 8.4 5.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 3.4 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.6 0.7 0.7 0.7 1.1 0.7 0.7 0.8 0.9 0.8 0.7 0.8 0.7 0.3 28.9 31.5 2.9 1.9 0.1 0.5 3.2 0.0 1.0 4.3 3.6 3.3 18.6 8.7 9.2 0.0 0.0 0.0 13.7 45.0 2.2 0.5 4.8 1.0 0.8 3.0 2.7 1.0 7.9 0.0 1.7 13.3 1.0 1.3 1.9 1.8 77.9 1.0 0.0 1.1 10.9 0.0 3.5 0.0 0.7 1.5 1.8 1.8 3.7 3.1 1.5 0.0 1.0 0.4 2.2 8.1 5.7 0.3 2.0 33.7 151.1 25.4 0.6 0.0 0.3 1.2 0.4 0.3 0.2 0.9 0.0 1.4 1.8 11.9 0.7 ABCG2 "ABCP, BCRP, CD338, EST157481, MXR" ENSG00000118777 "ATP binding cassette subfamily G member 2 (Junior blood group)" Q9UNQ0 4 88090150-88231628 "Cancer-related genes, CD markers, Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Transport Translocase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 88.3" "Cell type enhanced" "Detected in many" "Distal enterocytes: 106.7;Extravillous trophoblasts: 81.7;Hofbauer cells: 137.4;Microglial cells: 185.5;Proximal enterocytes: 216.6" "Cancer enhanced" "Detected in many" "glioma: 9.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 2.2" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 43.5;BEWO: 75.8;MCF7: 26.2;OE19: 58.6;RPMI-8226: 38.9;SuSa: 26.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB037299, HPA054719" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 28: BEWO - Transcription regulation" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "CAB037299: AB_476804, HPA054719: " "unprognostic (5.04e-1)" "unprognostic (3.05e-2)" "unprognostic (2.01e-1)" "unprognostic (1.10e-1)" "unprognostic (1.01e-3)" "unprognostic (9.19e-2)" "unprognostic (1.09e-1)" "unprognostic (1.30e-1)" "unprognostic (9.14e-2)" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (4.52e-2)" "unprognostic (1.67e-3)" "unprognostic (8.82e-3)" "unprognostic (7.04e-2)" "unprognostic (1.30e-1)" "unprognostic (1.92e-1)" 2.3 4.0 30.8 1.0 29.1 2.3 4.0 30.0 33.1 22.1 17.4 15.7 48.2 23.1 6.8 2.3 9.8 5.1 2.9 25.4 32.3 3.5 36.0 5.1 1.2 40.1 31.3 8.3 0.8 4.4 8.9 11.7 40.1 7.1 13.9 2.5 5.0 33.8 0.3 0.6 88.3 19.8 31.1 1.4 1.9 3.0 40.0 1.3 6.4 0.9 2.0 2.3 4.0 31.9 1.7 43.5 11.9 0.0 0.4 0.0 75.8 1.9 1.3 2.1 3.5 9.8 0.5 0.0 0.4 0.3 5.4 13.2 0.4 1.2 3.1 13.2 1.9 0.6 0.3 13.0 0.0 0.6 0.1 0.2 5.1 4.8 0.3 1.2 4.1 1.0 1.1 0.0 1.3 26.2 6.3 0.2 4.1 58.6 0.0 3.2 0.0 38.9 0.1 9.5 0.2 0.5 8.9 0.9 1.2 26.1 0.3 0.1 0.0 1.7 1.6 0.4 0.2 11.9 4.7 0.0 3.1 0.0 1.8 0.0 0.0 0.0 0.7 0.0 2.2 0.0 0.2 0.2 0.0 0.5 0.2 0.1 0.0 1.1 0.1 0.2 0.8 0.2 30.8 29.1 30.0 33.1 25.4 32.3 40.1 31.3 40.1 31.1 40.0 31.9 9.4 3.2 1.1 3.9 0.9 3.8 0.3 0.0 0.0 0.4 24.3 1.9 1.6 1.5 0.2 0.0 0.0 16.8 0.6 106.7 1.9 0.0 3.3 0.4 3.8 45.8 3.0 20.6 1.1 0.2 81.7 2.4 0.5 0.5 5.7 0.2 31.4 23.4 137.4 0.0 0.7 12.0 0.0 1.3 2.5 1.2 1.2 2.8 5.4 185.5 0.1 0.7 2.1 11.1 0.9 0.1 44.3 0.4 2.0 0.2 216.6 7.6 0.8 0.9 0.0 0.4 4.3 1.0 4.3 1.1 0.4 37.6 1.0 4.3 6.1 0.2 ABI1 "ABI-1, E3B1, SSH3BP1" ENSG00000136754 "Abl interactor 1" Q8IZP0 10 26746593-26861087 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Host-virus interaction" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 278.2;Suprabasal keratinocytes: 270.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008375, HPA068407" Approved Approved "Plasma membrane,Cell Junctions" NA NA 440000 "Cluster 5: Granulocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "CAB008375: AB_592744, HPA068407: AB_2685983" "unprognostic (2.83e-3)" "unprognostic (8.69e-2)" "unprognostic (1.12e-1)" "unprognostic (3.96e-1)" "unprognostic (2.51e-2)" "unprognostic (9.24e-3)" "unprognostic (1.88e-3)" "unprognostic (2.03e-1)" "unprognostic (6.04e-2)" "unprognostic (4.38e-1)" "unprognostic (2.40e-2)" "unprognostic (5.48e-2)" "unprognostic (1.98e-1)" "unprognostic (1.07e-1)" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.18e-1)" 28.9 16.2 28.5 35.0 29.2 83.8 29.8 28.3 38.9 30.4 20.9 32.0 32.4 23.6 19.2 53.0 23.8 24.9 16.3 37.4 28.8 27.6 24.9 28.1 48.1 24.7 26.8 26.6 19.9 20.1 12.9 28.3 25.4 20.8 33.0 18.9 32.9 19.1 20.0 42.9 34.1 23.8 26.2 32.3 31.8 14.2 28.0 44.5 22.6 19.6 53.7 34.7 36.5 27.1 55.0 28.6 21.1 21.9 34.4 39.5 34.1 50.9 31.2 35.0 37.5 33.7 61.7 101.1 23.2 51.7 23.0 57.7 28.0 37.0 41.0 65.2 24.2 44.5 18.0 29.0 23.6 23.2 43.9 28.1 54.6 35.3 21.8 41.5 43.7 33.5 30.7 67.2 40.5 25.4 49.8 26.0 18.8 37.5 13.5 51.4 41.2 69.2 48.0 22.9 17.1 18.5 41.3 44.5 46.8 29.4 27.7 35.5 50.6 27.3 33.2 34.4 25.5 15.0 24.0 108.7 38.7 61.1 17.4 77.3 35.5 91.4 42.1 43.2 40.8 57.2 40.9 48.5 39.4 47.7 37.7 41.7 64.3 35.8 45.4 34.1 76.5 57.2 28.5 29.2 28.3 38.9 37.4 28.8 24.7 26.8 25.4 26.2 28.0 27.1 44.4 41.7 37.7 278.2 89.3 246.2 127.9 74.0 123.5 9.6 40.5 26.5 23.2 38.6 73.5 25.8 2.1 36.4 75.7 69.7 13.7 56.3 11.3 72.1 41.3 41.9 44.9 43.8 81.6 52.1 46.9 45.9 42.3 111.5 57.7 22.3 32.9 25.6 75.8 16.8 133.7 54.9 83.4 80.5 116.3 5.7 22.1 92.1 92.5 106.8 89.8 48.2 73.2 128.7 47.4 82.2 52.1 22.2 56.8 132.5 52.7 39.0 86.2 10.0 32.9 29.8 40.3 14.7 10.8 109.6 270.6 77.2 71.0 27.2 41.3 195.4 AC005324.2 ENSG00000251537 "Novel tripartite motif-containing 16 (TRIM16) and CMT1A duplicated region transcript 1 (CDRT1) protein" 17 15571491-15651653 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;CAPAN-2: 1.1;HaCaT: 2.1;HeLa: 1.1" "HPA023623, HPA066431" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Epithelial cell lines - Epithelial cell function" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (3.45e-2)" "unprognostic (1.41e-1)" "unprognostic (1.93e-1)" "unprognostic (2.48e-1)" "unprognostic (1.24e-2)" "unprognostic (3.52e-2)" "unprognostic (2.87e-3)" "unprognostic (1.93e-1)" "unprognostic (2.98e-2)" "unprognostic (4.39e-2)" "unprognostic (4.81e-3)" "unprognostic (6.35e-3)" "unprognostic (1.80e-11)" "unprognostic (1.95e-1)" "unprognostic (1.36e-1)" "unprognostic (5.30e-2)" "unprognostic (3.09e-1)" 0.1 0.3 0.1 0.0 0.1 0.0 0.0 0.1 0.2 0.2 0.1 0.0 0.1 0.0 0.0 0.6 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.4 0.2 0.2 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.0 0.3 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC008403.1 ENSG00000268465 "Novel protein" 19 48465837-48472431 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "intestine: 1.2;retina: 5.2;testis: 1.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.1;LHCN-M2: 1.4;NB-4: 1.5;U-698: 2.2" HPA060662 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Plasma membrane, Cytosol" "HPA060662: AB_2732652" 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.8 0.1 0.0 1.2 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 5.2 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.1 0.1 1.6 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 1.1 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.8 0.9 0.5 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.7 0.1 0.0 1.4 0.0 0.0 1.5 0.7 0.7 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.3 0.3 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.8 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 AC020907.6 ENSG00000285526 "Novel protein" 19 35106510-35124297 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 3.3;choroid plexus: 3.1;salivary gland: 7.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 3.9;Club cells: 1.3;Respiratory ciliated cells: 2.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "SCLC-21H: 6.2;WM-115: 8.9" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "spinal cord: 3.8" HPA010856 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 17: WM-115 - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" 0.0 0.0 2.4 0.0 3.1 0.0 0.4 2.7 3.2 1.4 3.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 2.2 2.4 0.0 0.1 0.0 0.0 2.9 2.7 0.0 1.8 0.0 0.2 2.6 0.3 0.0 0.2 7.3 0.1 0.0 1.6 0.0 0.0 2.3 0.0 0.5 0.0 2.6 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.3 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 3.1 2.7 3.2 2.2 2.4 2.9 2.7 2.6 2.3 2.6 3.3 0.0 6.4 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ACKR3 "CMKOR1, CXCR7, GPR159, RDC1" ENSG00000144476 "Atypical chemokine receptor 3" P25106 2 236567787-236582354 "Cancer-related genes, G-protein coupled receptors, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 39.6;Endothelial cells: 59.8;Fibroblasts: 171.2;Smooth muscle cells: 37.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "NK-cells: 4.7;T-cells: 3.8" "Cell line enhanced" "Detected in many" "HeLa: 103.7;MCF7: 80.0;RT4: 312.3;SiHa: 97.0;U-2197: 328.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA032003, HPA049718" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA032003: AB_2674107, HPA049718: AB_2680859" "unprognostic (1.65e-2)" "prognostic unfavorable (4.64e-4)" "unprognostic (2.50e-1)" "unprognostic (1.92e-3)" "unprognostic (2.10e-1)" "unprognostic (1.23e-1)" "unprognostic (7.34e-3)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "unprognostic (1.35e-1)" "unprognostic (9.70e-3)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.76e-6)" "prognostic unfavorable (2.01e-4)" "unprognostic (9.71e-2)" "unprognostic (8.57e-3)" "prognostic unfavorable (2.93e-4)" 116.2 5.2 13.0 14.3 13.5 3.5 70.4 13.1 15.6 29.2 18.3 38.7 11.8 17.3 10.5 25.0 33.7 30.8 68.5 13.7 18.9 11.3 28.3 26.3 10.5 22.3 16.0 15.9 37.9 5.0 24.4 123.3 14.4 20.1 24.7 1.7 21.4 16.8 35.4 38.1 34.1 24.2 14.3 56.0 27.9 14.6 14.5 6.4 58.1 37.9 5.6 107.0 38.2 13.6 0.0 0.1 6.3 0.0 10.5 0.2 44.9 2.6 1.4 2.3 4.6 0.5 0.1 0.0 5.1 0.2 16.9 68.0 0.2 24.0 0.4 0.1 0.0 0.1 103.7 0.2 0.1 0.2 0.1 3.2 61.0 0.3 0.0 15.4 11.2 0.3 1.2 0.1 0.0 80.0 0.2 0.2 11.0 0.0 0.7 0.1 7.6 0.8 0.0 312.3 0.4 0.1 97.0 0.5 0.0 23.9 0.0 0.3 0.0 0.8 23.3 328.5 0.1 1.4 0.0 0.1 1.2 6.6 0.5 0.0 0.1 0.0 2.5 0.2 3.8 0.3 1.3 3.2 0.1 0.6 1.1 1.5 0.0 4.7 0.4 0.0 2.0 0.5 13.0 13.5 13.1 15.6 13.7 18.9 22.3 16.0 14.4 14.3 14.5 13.6 33.2 9.6 4.8 20.5 1.1 22.0 0.2 39.6 1.2 1.7 0.2 1.0 9.1 0.0 24.8 0.0 0.0 0.1 0.7 1.0 0.0 0.2 0.9 13.5 24.2 59.8 0.0 0.0 0.7 10.4 0.8 171.2 1.1 24.8 6.3 6.3 33.5 2.5 0.8 0.0 2.3 0.1 6.1 4.1 10.1 0.4 1.5 6.9 1.8 12.2 0.8 0.1 1.0 1.0 0.1 1.3 5.3 1.2 0.5 0.5 3.3 0.9 5.8 0.1 0.0 35.7 37.1 0.2 0.3 1.1 15.9 0.3 1.5 1.1 0.2 2.6 ACTR6 "ARP6, FLJ13433" ENSG00000075089 "Actin related protein 6" Q9GZN1 12 100199122-100241865 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 135.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038587, HPA038588" Uncertain Approved "Plasma membrane,Cytosol" No No "Cluster 33: Neutrophils - Chromatin organization" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA038587: AB_10670781, HPA038588: AB_10672719" "unprognostic (1.24e-2)" "unprognostic (8.43e-3)" "unprognostic (1.81e-1)" "unprognostic (1.14e-1)" "unprognostic (1.70e-1)" "unprognostic (1.24e-2)" "prognostic unfavorable (7.70e-9)" "unprognostic (4.11e-2)" "unprognostic (1.09e-1)" "unprognostic (1.05e-1)" "unprognostic (6.98e-2)" "unprognostic (3.99e-1)" "unprognostic (5.32e-2)" "unprognostic (4.30e-2)" "unprognostic (3.22e-1)" "unprognostic (6.67e-3)" "unprognostic (3.40e-2)" 15.0 16.7 17.6 12.8 17.7 7.4 28.9 18.2 24.5 13.9 17.9 14.6 15.2 15.2 18.1 13.8 14.2 10.3 17.5 18.2 19.8 22.1 19.6 12.2 20.8 18.0 18.6 17.9 5.0 20.8 4.5 17.0 19.1 16.8 15.3 20.6 15.3 15.9 14.3 13.6 14.4 14.4 18.3 16.1 10.6 21.3 17.7 20.4 16.3 15.8 19.2 17.1 4.5 20.8 60.2 23.5 27.1 35.9 22.4 28.3 63.3 26.0 22.6 25.0 18.2 15.2 17.8 32.9 24.7 19.5 18.8 23.0 36.5 22.5 34.3 48.9 33.8 22.8 22.2 17.7 23.6 33.7 17.7 17.4 27.7 20.2 25.8 38.5 28.9 38.0 36.9 10.5 29.2 15.5 33.7 50.8 31.6 22.5 34.2 27.0 27.3 41.4 27.3 35.8 24.8 47.0 35.3 62.5 36.5 22.4 40.6 39.5 18.8 18.4 12.3 20.5 23.7 23.6 55.6 42.8 12.1 21.2 21.7 5.7 6.4 10.0 15.2 11.5 19.3 12.6 17.9 20.3 8.2 12.1 19.4 19.6 3.0 19.4 13.2 12.0 20.5 12.1 17.6 17.7 18.2 24.5 18.2 19.8 18.0 18.6 19.1 18.3 17.7 20.8 33.5 16.0 17.7 6.5 25.8 22.9 36.2 72.4 29.6 32.7 26.5 23.9 34.8 8.6 38.1 23.9 18.8 55.6 36.9 9.9 46.9 21.4 135.2 56.8 27.7 20.7 12.5 21.7 20.9 12.0 68.4 25.0 12.2 28.9 33.0 19.1 16.1 16.4 23.7 33.7 23.2 11.3 73.2 19.1 13.4 34.3 20.2 17.5 32.0 13.1 19.5 27.0 25.7 17.1 17.4 13.2 10.0 22.6 19.7 24.7 11.7 67.9 67.9 32.8 32.9 27.8 36.8 80.8 19.9 23.8 19.7 96.0 36.6 23.8 13.3 33.8 ADA ADA1 ENSG00000196839 "Adenosine deaminase" P00813 20 44619522-44652233 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell adhesion, Nucleotide metabolism" Hydrolase "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "intestine: 507.2;lymphoid tissue: 259.0" "Cell type enhanced" "Detected in many" "dendritic cells: 76.4;Extravillous trophoblasts: 128.2;NK-cells: 56.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "intermediate monocyte: 168.5;NK-cell: 94.5;non-classical monocyte: 362.8;plasmacytoid DC: 218.6" "Group enriched" "Detected in all" 4 "dendritic cells: 218.6;monocytes: 362.8;NK-cells: 94.5" "Group enriched" "Detected in many" 5 "JURKAT: 570.9;MOLT-4: 1915.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001399, CAB004307, HPA023884" Enhanced Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 9: Intestine - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Cytosol "CAB004307: AB_626634, HPA001399: AB_1078099, HPA023884: AB_1844573" "unprognostic (4.30e-2)" "unprognostic (6.89e-2)" "unprognostic (3.96e-2)" "prognostic unfavorable (1.23e-7)" "unprognostic (9.33e-2)" "unprognostic (9.07e-3)" "prognostic unfavorable (6.77e-5)" "prognostic unfavorable (2.20e-4)" "unprognostic (1.59e-1)" "unprognostic (2.16e-1)" "unprognostic (3.66e-2)" "unprognostic (3.48e-1)" "prognostic unfavorable (2.94e-14)" "unprognostic (2.29e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-1)" "unprognostic (1.82e-1)" 16.6 6.3 6.9 18.5 8.2 20.2 10.9 6.8 9.4 7.3 5.6 5.7 507.2 3.8 1.7 9.0 5.6 9.2 17.8 6.9 7.0 3.3 4.4 6.2 33.4 7.2 8.2 2.1 5.3 1.5 1.3 4.6 7.2 4.3 3.6 0.3 4.7 2.8 5.3 6.0 17.9 5.7 6.1 17.5 46.0 2.4 8.7 259.0 5.8 6.4 26.4 9.3 5.4 8.8 14.0 37.7 19.2 13.2 35.6 48.7 30.5 13.7 7.8 13.2 9.3 17.5 14.8 38.4 15.8 17.9 24.7 2.2 13.2 55.1 7.3 2.9 17.2 7.8 6.6 13.5 15.0 6.3 20.3 234.3 23.2 5.1 9.0 12.6 50.3 570.9 20.4 30.7 6.0 33.1 1915.5 28.9 5.2 17.2 13.5 102.3 25.8 95.0 2.3 0.0 0.7 9.3 20.2 4.4 24.2 24.0 4.5 19.1 16.9 10.1 18.6 20.5 2.8 40.1 27.3 82.3 3.5 32.5 9.0 0.5 9.8 1.2 43.3 168.5 27.8 7.5 35.5 51.0 35.2 7.6 27.3 38.6 2.5 94.5 362.8 218.6 29.8 57.4 6.9 8.2 6.8 9.4 6.9 7.0 7.2 8.2 7.2 6.1 8.7 8.8 18.2 0.0 1.9 2.9 13.5 12.9 3.4 10.0 13.6 0.0 2.7 3.2 2.1 0.0 4.8 1.8 0.0 2.9 76.4 0.8 0.0 3.7 0.4 0.7 9.1 17.0 0.0 10.7 0.2 19.7 128.2 19.7 14.8 0.8 0.0 3.5 7.1 3.6 28.5 0.0 0.2 1.5 10.2 20.8 25.5 1.8 42.3 27.6 8.8 3.7 37.4 3.8 56.7 0.5 9.4 10.7 0.3 2.6 31.4 6.0 0.7 3.0 2.4 0.0 13.1 1.9 14.1 0.3 6.2 12.9 13.9 3.7 30.9 6.8 4.9 2.7 ADAM10 "CD156C, HsT18717, kuz, MADM" ENSG00000137845 "ADAM metallopeptidase domain 10" O14672 15 58588809-58749791 "Cancer-related genes, CD markers, Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Notch signaling pathway" "Hydrolase, Metalloprotease, Protease" "Alzheimer disease, Amyloidosis, Cancer-related genes, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 377.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-2197: 296.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001709, HPA050670" Approved Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 690000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 18: U-2197 - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "CAB001709: , HPA050670: " "unprognostic (1.43e-1)" "unprognostic (1.38e-1)" "unprognostic (2.77e-1)" "unprognostic (5.04e-2)" "unprognostic (3.09e-1)" "unprognostic (2.70e-3)" "unprognostic (7.48e-2)" "prognostic unfavorable (8.46e-5)" "unprognostic (3.99e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (1.90e-4)" "unprognostic (6.69e-2)" "unprognostic (2.57e-2)" "unprognostic (2.57e-3)" "unprognostic (9.14e-2)" "unprognostic (2.09e-2)" "unprognostic (1.60e-2)" 14.9 8.7 11.4 19.0 18.6 18.7 15.2 20.2 15.0 16.0 9.7 22.2 15.9 16.3 7.7 15.4 13.9 18.9 12.1 12.2 12.7 18.0 16.1 21.0 22.2 18.2 17.6 14.1 8.8 7.9 8.2 29.0 17.5 25.2 17.2 10.8 9.3 12.2 6.1 16.9 17.5 13.3 13.7 29.0 20.3 8.5 15.5 42.7 28.6 7.1 16.4 28.0 10.4 25.2 48.4 88.5 27.6 31.2 34.8 49.8 70.0 39.0 116.0 28.6 39.1 39.9 62.6 22.7 118.0 35.2 49.2 95.9 16.8 43.5 37.0 30.1 19.3 38.7 35.1 42.1 40.8 25.0 103.8 44.4 30.0 19.9 29.2 41.1 55.6 45.0 24.5 57.9 50.4 15.4 89.5 32.0 40.2 15.4 14.6 36.4 91.6 57.1 66.6 121.4 29.9 20.3 44.0 52.8 73.1 60.0 30.4 55.0 41.4 37.1 41.2 296.6 39.6 30.7 70.7 23.5 54.1 50.8 67.3 30.9 36.2 19.2 12.8 41.1 19.2 8.3 12.7 11.6 23.6 9.6 12.7 10.8 51.5 17.7 48.6 10.2 18.2 25.8 11.4 18.6 20.2 15.0 12.2 12.7 18.2 17.6 17.5 13.7 15.5 25.2 60.1 83.3 50.8 83.2 37.9 26.6 30.7 33.3 33.0 22.7 61.6 30.9 40.0 30.0 46.7 80.9 27.1 35.6 69.4 79.0 1.9 56.0 21.2 39.5 56.4 72.5 36.1 20.8 106.1 31.8 57.8 36.1 53.0 74.0 30.3 31.5 71.4 36.2 63.8 45.4 96.2 43.6 36.7 90.1 28.9 19.4 18.0 77.9 46.2 147.1 69.0 30.6 44.3 75.9 377.6 48.9 48.1 17.0 51.0 89.1 45.1 23.7 41.2 33.4 13.1 34.4 42.8 20.3 17.8 39.5 22.3 26.5 51.3 34.1 39.5 83.9 ADAM28 "ADAM23, eMDCII, MDC-Lm, MDC-Ls" ENSG00000042980 "ADAM metallopeptidase domain 28" Q9UKQ2 8 24294069-24359014 "Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "epididymis: 357.5;stomach 1: 110.3" "Cell type enhanced" "Detected in many" "B-cells: 240.9;Club cells: 62.9;Gastric mucus-secreting cells: 141.7;Microglial cells: 233.3" "Cancer enhanced" "Detected in many" "pancreatic cancer: 9.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 71.6;naive B-cell: 87.0" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "CAPAN-2: 27.8;OE19: 8.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA074034 Enhanced Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" Mitochondria "HPA074034: AB_2686654" "unprognostic (4.23e-2)" "unprognostic (1.01e-2)" "unprognostic (2.06e-2)" "prognostic favorable (3.17e-4)" "unprognostic (2.89e-1)" "unprognostic (2.55e-2)" "unprognostic (5.59e-2)" "unprognostic (1.53e-1)" "unprognostic (4.71e-1)" "unprognostic (1.35e-2)" "unprognostic (3.77e-3)" "unprognostic (7.77e-2)" "unprognostic (3.97e-3)" "unprognostic (1.71e-2)" "unprognostic (1.30e-1)" "unprognostic (2.60e-1)" "unprognostic (1.62e-1)" 2.2 2.2 5.9 24.7 4.6 9.3 3.9 7.1 5.0 16.1 4.0 14.3 8.8 6.9 357.5 2.8 12.3 40.2 1.0 5.8 8.8 5.1 1.2 3.9 26.7 12.0 9.3 2.3 3.5 1.1 18.5 3.7 11.7 5.3 12.1 1.3 15.9 5.7 0.3 3.3 24.7 2.9 9.8 19.9 110.3 0.7 10.1 5.1 1.9 0.4 32.3 11.3 1.7 18.6 0.0 0.4 0.1 0.0 0.0 0.4 0.1 0.1 0.2 0.0 0.0 1.1 27.8 0.3 0.8 0.0 0.9 0.1 0.0 0.8 0.1 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.2 3.7 0.7 8.8 0.1 0.1 0.0 0.4 0.6 0.8 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.3 0.1 0.1 1.2 2.5 0.1 2.1 1.0 0.2 42.4 2.5 18.5 0.0 0.6 0.0 71.6 0.1 0.0 21.0 87.0 0.1 0.0 4.3 2.7 0.2 1.1 0.1 2.5 5.9 4.6 7.1 5.0 5.8 8.8 12.0 9.3 11.7 9.8 10.1 18.6 1.5 3.2 6.0 0.7 240.9 0.9 3.0 36.9 0.0 0.1 2.3 2.2 2.0 28.6 62.9 3.7 0.0 0.4 9.9 0.7 0.0 7.9 1.3 7.6 1.0 3.7 0.0 8.2 4.3 3.5 8.7 3.9 141.7 18.4 2.5 0.0 0.0 0.0 9.4 0.0 2.7 0.4 28.5 12.3 30.9 1.8 0.6 46.4 5.4 233.3 7.8 0.1 23.7 3.5 1.6 55.7 0.1 0.4 43.3 1.5 0.6 4.4 13.1 0.1 6.6 0.0 1.1 0.4 0.2 0.7 0.6 0.5 9.0 6.4 1.3 7.6 ADAM33 "C20orf153, dJ964F7.1, DKFZp434K0521" ENSG00000149451 "ADAM metallopeptidase domain 33" Q9BZ11 20 3667965-3682246 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Hydrolase, Metalloprotease, Protease" Asthma "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 280.4" "Cell type enhanced" "Detected in some" "Endometrial stromal cells: 40.8;Fibroblasts: 45.2;Leydig cells: 22.7;Microglial cells: 18.7;Smooth muscle cells: 17.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 82.4;ASC TERT1: 104.9;BJ: 38.5;BJ hTERT+: 64.7;fHDF/TERT166: 38.9;U-2197: 50.9" "Region enhanced" "Detected in single" "cerebral cortex: 1.0" "Low region specificity" "Detected in all" "HPA067152, HPA071758" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear speckles" "HPA067152: AB_2685791, HPA071758: " "unprognostic (1.10e-1)" "unprognostic (3.02e-2)" "unprognostic (2.24e-2)" "unprognostic (3.35e-3)" "unprognostic (4.39e-3)" "unprognostic (7.43e-4)" "unprognostic (7.14e-3)" "unprognostic (1.67e-1)" "unprognostic (1.78e-3)" "unprognostic (1.28e-1)" "unprognostic (1.26e-1)" "unprognostic (3.56e-1)" "unprognostic (2.75e-11)" "unprognostic (1.05e-2)" "unprognostic (1.92e-1)" "unprognostic (3.21e-5)" "unprognostic (3.10e-3)" 53.3 3.8 7.8 10.5 8.5 0.1 47.4 5.8 12.3 280.4 8.4 157.2 11.0 151.8 19.0 31.6 106.9 32.8 26.7 6.7 9.3 3.9 2.0 18.0 6.2 16.0 8.0 58.7 6.0 0.5 6.9 12.7 16.4 87.0 12.1 1.0 19.6 57.5 9.1 22.0 43.4 53.0 5.9 8.3 44.8 22.5 6.9 0.9 18.4 14.1 2.2 125.4 159.0 6.2 0.0 0.0 0.2 0.0 82.4 104.9 0.2 38.5 64.7 11.2 21.3 0.1 0.0 0.0 0.2 38.9 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 13.0 0.0 0.0 18.2 0.0 4.0 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.0 2.8 0.2 2.9 0.0 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.7 0.1 0.1 0.0 0.2 0.0 50.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.8 8.5 5.8 12.3 6.7 9.3 16.0 8.0 16.4 5.9 6.9 6.2 3.9 0.0 0.0 7.2 0.1 5.5 0.1 0.0 0.6 0.0 0.3 0.3 3.3 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.5 1.8 40.8 2.4 0.0 0.0 1.3 0.0 0.1 45.2 2.6 1.2 0.0 3.1 1.8 0.0 0.5 0.0 11.4 0.0 0.0 0.3 8.8 0.8 22.7 0.8 3.6 18.7 0.0 2.2 0.0 8.0 0.1 0.0 0.0 10.1 0.0 0.2 0.0 0.9 0.0 0.1 6.6 6.8 17.1 0.7 0.5 0.3 3.1 0.5 0.7 0.0 0.0 0.1 ADAMTS2 "ADAM-TS2, ADAMTS-3, hPCPNI, NPI, PCINP" ENSG00000087116 "ADAM metallopeptidase with thrombospondin type 1 motif 2" O95450 5 179110853-179345461 "Disease related genes, Enzymes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Ehlers-Danlos syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 32.2;Excitatory neurons: 17.9;Fibroblasts: 30.7;Hepatic stellate cells: 17.2;Kupffer cells: 71.4;Sertoli cells: 26.3;Smooth muscle cells: 20.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 36.0;ASC TERT1: 35.8;BJ: 31.4;fHDF/TERT166: 39.3;HHSteC: 115.5;HSkMC: 94.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028363, HPA028444" Uncertain Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 2000000 "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA028363: , HPA028444: AB_10601964" "unprognostic (6.78e-2)" "unprognostic (7.83e-2)" "unprognostic (1.13e-1)" "unprognostic (5.50e-2)" "unprognostic (8.85e-3)" "unprognostic (4.80e-2)" "unprognostic (1.09e-1)" "unprognostic (2.22e-2)" "unprognostic (1.58e-1)" "unprognostic (1.91e-2)" "unprognostic (2.08e-1)" "unprognostic (2.45e-1)" "prognostic unfavorable (1.71e-8)" "unprognostic (1.32e-3)" "unprognostic (1.03e-2)" "unprognostic (7.16e-3)" "unprognostic (1.48e-2)" 36.9 10.9 0.8 2.4 4.2 0.3 22.7 0.9 3.5 20.6 0.9 10.5 1.4 21.7 0.5 5.5 15.5 6.1 22.3 0.5 0.9 7.5 15.8 29.6 1.8 4.5 3.3 12.1 5.8 0.4 15.1 9.7 4.2 9.0 1.4 0.2 5.3 1.8 2.9 9.4 11.6 9.1 0.2 38.4 9.3 3.9 2.5 0.4 6.8 0.8 0.6 15.0 16.7 2.2 0.0 0.0 0.1 0.7 36.0 35.8 0.0 31.4 5.4 11.5 12.4 0.1 0.0 0.0 0.2 39.3 0.7 0.1 1.8 0.0 5.1 0.0 1.5 0.0 0.1 2.3 115.5 0.0 0.0 94.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.1 0.8 0.8 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.9 1.2 0.1 0.0 0.4 1.9 0.0 10.7 0.0 19.1 3.0 24.5 0.0 0.3 0.0 0.0 0.9 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.8 4.2 0.9 3.5 0.5 0.9 4.5 3.3 4.2 0.2 2.5 2.2 3.3 0.0 1.1 1.6 0.1 2.2 0.4 0.0 2.2 0.3 0.2 5.2 1.5 1.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.3 0.9 32.2 1.4 0.0 0.0 17.9 0.0 0.3 30.7 0.0 0.8 1.3 6.5 17.2 0.5 5.1 0.0 8.5 0.0 0.0 71.4 4.4 3.4 5.0 10.4 0.0 4.7 0.3 0.1 0.0 3.0 2.4 0.5 0.0 12.8 0.1 0.4 0.0 0.2 0.0 0.0 26.3 4.7 20.4 2.1 4.8 0.2 2.7 0.0 0.4 0.6 0.0 0.1 ADAMTSL4 "DKFZP434K1772, TSRC1" ENSG00000143382 "ADAMTS like 4" Q6UY14 1 150549369-150560937 "Disease related genes, Human disease related genes, Predicted secreted proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 146.7;Endometrial stromal cells: 36.9;Extravillous trophoblasts: 46.4;Fibroblasts: 34.5;Hofbauer cells: 34.0;Syncytiotrophoblasts: 99.5" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 11.1" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC TERT1: 92.0;BEWO: 200.3;HSkMC: 43.8;K-562: 67.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA006279 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 110000000 "Cluster 14: Monocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA006279: AB_1078102" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "prognostic unfavorable (1.86e-4)" "unprognostic (8.09e-4)" "prognostic unfavorable (2.43e-4)" "unprognostic (1.09e-1)" "unprognostic (1.65e-1)" "unprognostic (7.52e-2)" "unprognostic (3.56e-2)" "unprognostic (1.68e-2)" "unprognostic (1.28e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.35e-7)" "unprognostic (1.90e-1)" "unprognostic (5.23e-2)" "unprognostic (1.44e-2)" "unprognostic (7.40e-3)" 32.0 5.1 1.1 14.9 1.0 4.2 24.7 0.8 11.1 22.9 7.9 19.3 3.6 20.0 1.6 33.3 29.2 7.7 22.3 0.8 1.4 6.4 17.3 26.1 1.8 4.4 2.8 17.1 3.0 0.5 3.0 62.9 2.9 9.0 3.8 0.6 11.8 3.4 37.7 11.8 13.7 11.4 1.2 5.4 17.2 2.4 3.6 0.8 6.1 47.9 1.2 32.8 23.3 1.5 22.0 0.6 0.3 3.9 19.1 92.0 200.3 20.8 18.0 12.1 7.0 1.8 8.5 0.2 4.3 14.4 0.2 11.0 0.8 3.2 4.9 1.7 0.4 6.2 2.6 8.9 15.3 0.3 3.0 43.8 0.9 3.0 6.8 10.3 0.1 0.0 67.7 0.7 2.2 0.5 0.0 1.1 3.5 0.6 0.7 0.0 0.0 0.1 2.1 0.8 0.1 0.6 6.7 15.9 0.1 10.0 4.5 11.5 3.8 0.7 5.5 8.6 0.3 1.9 0.6 4.5 0.8 4.0 0.5 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 1.3 0.0 0.0 0.3 1.1 1.0 0.8 11.1 0.8 1.4 4.4 2.8 2.9 1.2 3.6 1.5 2.8 0.0 1.5 1.0 0.5 2.4 2.3 0.2 0.6 1.7 1.3 1.8 2.2 10.0 0.6 0.0 0.0 146.7 1.0 0.2 0.0 1.7 0.6 2.6 36.9 5.3 0.0 0.0 0.3 0.6 46.4 34.5 0.0 5.4 2.5 0.9 1.8 10.6 34.0 0.0 0.1 0.2 0.0 24.0 12.5 0.7 30.1 20.0 3.6 0.0 23.1 1.4 1.0 0.0 0.0 12.3 0.1 3.4 3.2 2.2 0.0 0.2 0.9 2.2 0.0 14.3 3.8 0.1 1.6 5.5 2.8 99.5 1.7 0.5 0.3 2.5 ADAP1 "CENTA1, GCS1L" ENSG00000105963 "ArfGAP with dual PH domains 1" O75689 7 897900-955407 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.9;intestine: 43.2" "Cell type enhanced" "Detected in many" "Distal enterocytes: 97.7;Intestinal goblet cells: 42.5;Oligodendrocytes: 43.6;Paneth cells: 64.4;Proximal enterocytes: 48.5;Undifferentiated cells: 50.6" "Cancer enhanced" "Detected in all" "colorectal cancer: 15.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 108.1;CAPAN-2: 74.1;HMC-1: 71.0;OE19: 191.5;THP-1: 122.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007033, HPA012049" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA007033: AB_1846529, HPA012049: AB_1846527" "unprognostic (2.45e-1)" "unprognostic (7.15e-2)" "prognostic unfavorable (5.25e-4)" "unprognostic (4.41e-2)" "unprognostic (1.97e-1)" "prognostic unfavorable (9.13e-4)" "unprognostic (3.06e-1)" "unprognostic (9.10e-3)" "unprognostic (1.70e-2)" "unprognostic (1.38e-1)" "unprognostic (5.74e-2)" "unprognostic (1.69e-1)" "prognostic favorable (4.13e-5)" "unprognostic (5.88e-2)" "unprognostic (1.58e-1)" "unprognostic (1.41e-1)" "unprognostic (1.79e-2)" 4.9 3.8 51.2 11.2 55.8 9.8 3.4 57.3 73.6 4.1 11.2 43.2 19.7 6.0 0.6 9.0 8.8 6.0 8.1 59.4 42.9 22.3 3.6 10.4 3.8 63.5 63.1 1.5 13.3 6.1 4.7 2.7 56.9 6.6 22.8 1.6 4.6 2.9 0.7 3.9 26.8 8.3 48.7 17.2 19.6 1.1 55.4 0.9 7.6 0.5 2.1 8.9 3.8 85.9 108.1 4.0 0.1 3.7 1.4 0.2 1.1 3.6 0.1 0.7 0.1 43.1 74.1 0.2 10.3 0.5 0.2 44.5 5.9 8.1 0.5 0.6 4.7 0.0 6.0 25.4 1.7 0.7 71.0 1.8 21.4 0.2 0.0 0.1 0.0 3.1 0.4 0.0 0.0 33.2 0.1 30.1 3.2 191.5 0.0 14.4 0.2 0.4 4.7 25.0 3.1 1.0 3.3 1.3 0.5 0.4 25.9 122.6 0.6 0.8 2.8 0.1 0.3 0.0 0.2 0.0 0.2 22.3 3.3 1.0 6.5 3.3 6.0 7.3 2.8 1.1 1.6 5.5 5.1 0.9 0.5 2.6 3.1 1.6 11.7 0.3 0.8 4.0 51.2 55.8 57.3 73.6 59.4 42.9 63.5 63.1 56.9 48.7 55.4 85.9 0.4 0.0 10.3 2.9 3.6 1.0 2.9 3.3 2.8 4.7 2.5 1.5 8.5 7.2 2.9 7.3 0.0 0.3 19.4 97.7 9.8 3.9 0.2 8.6 0.9 0.5 16.2 0.0 13.2 4.6 0.9 1.5 17.9 7.6 7.0 1.3 0.0 0.6 12.2 0.0 12.6 42.5 4.1 23.0 15.7 0.4 0.0 22.1 10.6 2.8 13.2 1.3 15.5 3.0 43.6 17.5 64.4 0.0 2.6 3.0 48.5 7.1 8.2 1.1 0.0 0.1 1.9 0.3 1.2 1.1 1.3 0.7 9.0 0.0 50.6 5.5 ADCK5 FLJ35454 ENSG00000173137 "AarF domain containing kinase 5" Q3MIX3 8 144373101-144393242 "Enzymes, Predicted membrane proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 61.7;Theca cells: 42.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025692, HPA028679" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA025692: AB_10599486, HPA028679: AB_10600226" "unprognostic (6.76e-2)" "unprognostic (1.66e-1)" "unprognostic (1.68e-2)" "unprognostic (8.96e-2)" "unprognostic (1.68e-2)" "unprognostic (1.00e-1)" "unprognostic (2.31e-3)" "unprognostic (6.45e-2)" "unprognostic (2.70e-1)" "unprognostic (4.25e-2)" "unprognostic (6.60e-2)" "unprognostic (2.03e-2)" "unprognostic (1.33e-3)" "unprognostic (1.39e-2)" "unprognostic (1.20e-1)" "unprognostic (3.47e-1)" "unprognostic (2.90e-2)" 3.1 9.1 1.3 1.5 1.3 0.9 3.4 1.1 2.6 4.5 0.9 6.7 4.8 3.7 0.2 6.4 3.7 0.5 4.1 1.4 1.1 4.3 6.4 2.8 1.1 1.4 1.1 4.5 5.0 0.8 3.5 0.6 1.3 4.1 0.7 0.5 4.1 0.8 4.0 5.2 8.4 0.4 0.9 5.7 4.4 6.7 1.2 1.1 3.6 0.7 0.5 4.0 4.2 1.2 2.5 3.1 0.7 2.1 0.5 0.5 3.7 2.2 1.2 1.8 0.7 3.6 2.7 1.1 1.5 0.5 0.6 3.2 0.1 2.2 0.1 2.8 1.0 2.9 2.6 3.9 1.6 0.7 2.2 1.0 1.4 0.6 0.7 0.9 1.2 2.1 1.9 1.9 0.9 6.9 2.2 2.9 0.4 2.3 2.3 2.8 1.0 2.0 1.2 2.3 0.4 1.1 3.1 2.4 1.8 0.5 2.1 1.9 0.8 0.8 3.2 2.2 1.5 0.9 0.3 1.0 1.9 2.5 1.3 0.9 2.0 1.2 1.1 2.7 1.3 0.9 1.3 0.8 3.2 2.7 1.3 0.7 0.4 1.0 2.7 2.0 2.1 1.3 1.3 1.3 1.1 2.6 1.4 1.1 1.4 1.1 1.3 0.9 1.2 1.2 5.8 3.2 1.7 4.9 6.5 4.1 3.3 10.2 2.2 10.3 5.0 6.1 2.3 7.2 6.9 5.5 16.7 4.3 6.6 33.5 3.9 9.3 8.2 3.7 4.2 5.0 8.4 3.0 7.6 7.1 11.2 4.5 20.4 4.8 8.9 16.2 2.5 8.2 8.0 3.3 8.3 31.2 12.2 5.5 4.3 11.3 5.9 5.0 3.6 2.8 9.1 6.4 7.2 4.0 2.4 9.5 16.8 7.2 3.7 2.7 61.7 6.9 9.5 16.3 13.1 2.5 4.4 26.5 19.2 4.7 5.1 2.5 4.8 42.3 25.4 3.1 ADD1 ENSG00000087274 "Adducin 1" P35611 4 2843857-2930076 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 402.4;Rod photoreceptor cells: 624.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009794, HPA035873, HPA035874" Enhanced Enhanced "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 19: B-cells - Humoral immune response" "Cluster 54: Non-specific - Microtubule organization" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "CAB009794: AB_633663, HPA035873: AB_2674836, HPA035874: AB_2674837" "unprognostic (1.79e-1)" "unprognostic (1.37e-1)" "unprognostic (1.66e-2)" "unprognostic (5.40e-3)" "unprognostic (1.90e-1)" "unprognostic (2.66e-2)" "unprognostic (5.07e-3)" "unprognostic (1.68e-2)" "unprognostic (3.52e-1)" "unprognostic (2.50e-1)" "prognostic favorable (3.94e-4)" "unprognostic (5.22e-2)" "prognostic favorable (1.29e-7)" "unprognostic (2.61e-2)" "unprognostic (1.12e-1)" "unprognostic (7.38e-2)" "unprognostic (4.03e-3)" 104.4 70.0 96.4 60.7 119.7 65.9 89.1 86.7 117.7 96.5 46.4 127.9 65.5 121.4 57.9 71.9 96.3 69.0 111.2 99.2 90.9 74.1 53.7 93.5 65.3 91.5 100.4 129.5 56.4 67.5 70.1 66.0 92.3 86.1 62.7 269.1 61.9 107.3 166.3 69.4 92.3 110.2 76.0 88.9 84.3 53.2 113.2 76.0 71.7 115.0 62.1 115.3 82.9 116.2 74.7 61.2 142.0 73.8 205.8 152.6 53.2 123.2 146.9 125.6 105.3 90.5 91.8 38.7 63.0 212.3 146.6 46.6 107.5 103.4 104.3 49.9 49.4 109.5 50.4 87.9 100.4 65.8 74.7 151.6 95.2 110.4 44.0 130.1 158.5 71.9 116.0 90.8 145.1 43.7 203.7 91.6 80.0 67.9 85.7 89.1 78.6 45.7 91.2 162.2 84.8 110.0 88.9 35.8 76.9 107.0 84.2 61.7 193.4 102.1 52.4 84.7 103.0 72.5 63.3 48.9 98.2 80.4 100.9 20.1 7.6 35.5 19.1 7.3 17.6 23.8 10.6 16.3 12.0 31.2 9.8 11.8 10.5 27.2 11.4 25.4 14.8 16.0 96.4 119.7 86.7 117.7 99.2 90.9 91.5 100.4 92.3 76.0 113.2 116.2 89.3 70.5 45.4 141.3 66.5 26.9 29.8 33.0 27.9 99.5 41.2 41.5 78.0 40.0 46.3 60.7 402.4 35.5 84.0 51.3 15.6 37.3 48.5 43.9 61.2 89.4 57.7 57.9 85.7 45.8 32.5 72.9 39.8 58.1 37.3 53.0 84.3 41.8 41.8 111.0 83.2 39.3 28.5 51.6 42.2 35.9 77.6 47.4 35.6 72.1 58.3 233.8 120.5 68.9 178.6 53.2 39.4 121.9 49.7 35.8 48.6 44.6 40.4 624.3 98.6 58.4 73.1 45.3 33.2 30.5 36.7 36.5 55.6 80.7 45.1 33.0 ADGRD1 "DKFZp434B1272, GPR133, PGR25" ENSG00000111452 "Adhesion G protein-coupled receptor D1" Q6QNK2 12 130953907-131141469 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 62.4" "Group enriched" "Detected in many" 4 "Alveolar cells type 1: 22.4;Alveolar cells type 2: 30.5;Cardiomyocytes: 47.0;Early spermatids: 16.2;Endometrial stromal cells: 50.2;Fibroblasts: 32.7;Late spermatids: 21.4;Leydig cells: 13.7;Microglial cells: 25.3;Peritubular cells: 15.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "classical monocyte: 2.0;intermediate monocyte: 2.3;myeloid DC: 1.1;non-classical monocyte: 1.8" "Group enriched" "Detected in many" 6 "dendritic cells: 1.1;monocytes: 2.3" "Cell line enhanced" "Detected in some" "BJ: 4.1;fHDF/TERT166: 4.7;HeLa: 7.6;HHSteC: 4.9;HMC-1: 13.0;U-2 OS: 6.1" "Region enhanced" "Detected in some" "basal ganglia: 5.1" "Low region specificity" "Detected in all" "HPA042395, HPA076279" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 7: Monocytes - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 3: HMC-1 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA042395: AB_10796906, HPA076279: " "unprognostic (3.21e-1)" "unprognostic (1.49e-4)" "unprognostic (1.32e-2)" "unprognostic (1.63e-1)" "unprognostic (4.40e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (9.27e-4)" "unprognostic (2.55e-3)" "unprognostic (1.63e-2)" "unprognostic (6.94e-2)" "unprognostic (1.11e-2)" "unprognostic (3.98e-2)" "unprognostic (4.79e-5)" "unprognostic (1.31e-3)" "unprognostic (4.58e-1)" "unprognostic (2.15e-2)" "unprognostic (1.77e-3)" 26.4 1.9 1.9 1.3 2.0 0.3 10.3 1.2 2.5 20.6 1.0 10.6 1.9 15.4 7.3 6.9 17.7 12.9 62.4 1.4 3.2 3.4 10.3 35.6 0.4 2.0 2.6 17.9 12.0 0.3 6.3 25.7 2.2 15.3 1.8 0.8 2.9 1.0 7.3 7.0 12.1 7.1 2.0 2.3 20.7 7.5 3.6 0.4 11.2 8.5 1.0 40.3 16.3 1.7 0.0 0.7 0.0 2.0 0.0 0.0 0.1 4.1 0.0 0.0 0.4 0.0 0.0 0.3 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 7.6 0.0 4.9 0.0 13.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.4 0.0 0.0 0.8 0.0 0.1 0.2 2.1 0.5 0.6 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.4 6.1 1.5 0.1 0.1 1.7 0.8 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.8 1.9 2.0 1.2 2.5 1.4 3.2 2.0 2.6 2.2 2.0 3.6 1.7 2.0 22.4 30.5 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 47.0 0.0 5.0 1.8 0.0 1.3 0.0 0.0 0.0 0.0 16.2 1.3 50.2 3.4 0.0 0.0 1.1 0.4 0.6 32.7 0.5 1.0 1.3 0.3 1.8 3.6 2.3 0.0 1.4 0.0 0.0 1.5 0.0 21.4 13.7 1.5 0.0 25.3 3.5 0.0 0.0 0.0 0.1 0.3 0.0 15.8 0.0 0.0 0.0 0.1 2.2 0.7 6.6 2.2 3.5 4.3 6.5 0.1 0.0 1.0 0.6 0.2 0.1 0.3 ADGRG2 "EDDM6, GPR64, HE6, TM7LN2" ENSG00000173698 "Adhesion G protein-coupled receptor G2" Q8IZP9 X 18989307-19122637 "Disease related genes, G-protein coupled receptors, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "epididymis: 1227.7" "Cell type enhanced" "Detected in some" "Cholangiocytes: 7.2;Endometrial stromal cells: 5.4;Fibroblasts: 5.3;Gastric mucus-secreting cells: 9.2;Oligodendrocyte precursor cells: 10.1;Oligodendrocytes: 7.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.9" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 6.0;BEWO: 7.3;HeLa: 5.9;NTERA-2: 6.4;RPMI-8226: 4.5;SH-SY5Y: 6.6;U-2197: 14.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA001478, HPA050029" Enhanced Approved "Plasma membrane,Cytosol" NA NA 22000000 "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA001478: AB_1078923, HPA050029: AB_2680996" "unprognostic (3.33e-2)" "unprognostic (3.20e-1)" "unprognostic (2.40e-1)" "unprognostic (2.55e-2)" "unprognostic (1.58e-1)" "unprognostic (4.43e-3)" "unprognostic (2.63e-4)" "unprognostic (2.66e-1)" "unprognostic (1.27e-3)" "unprognostic (1.12e-1)" "unprognostic (1.78e-2)" "unprognostic (1.07e-1)" "unprognostic (3.54e-7)" "unprognostic (6.37e-2)" "unprognostic (3.19e-1)" "unprognostic (2.83e-1)" "unprognostic (1.35e-1)" 3.9 0.3 0.1 0.9 0.1 0.0 2.0 0.0 1.1 1.0 0.0 0.5 0.5 1.0 1227.7 0.5 16.5 1.6 1.3 0.8 0.7 0.4 0.7 1.3 5.0 0.4 1.5 0.2 1.2 163.4 1.1 0.5 0.6 2.1 0.4 0.9 8.5 3.6 0.2 0.4 1.1 0.4 0.1 2.4 9.0 1.9 0.3 6.6 1.6 1.1 3.7 0.8 1.0 0.2 0.2 6.0 0.0 0.0 0.1 0.9 7.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 2.4 0.0 5.9 0.2 0.8 0.0 0.0 0.1 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.2 0.0 1.0 0.0 2.2 6.4 0.0 2.0 0.0 0.0 4.5 0.0 1.2 2.2 6.6 1.5 0.1 0.0 1.1 0.1 0.1 0.1 0.2 0.4 14.6 2.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 1.1 0.8 0.7 0.4 1.5 0.6 0.1 0.3 0.2 0.6 0.0 0.0 3.6 0.1 0.0 0.1 0.0 0.0 0.6 1.2 1.1 1.0 7.2 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.4 0.1 1.1 5.4 0.6 0.0 0.0 4.4 0.2 0.3 5.3 9.2 3.2 0.0 0.2 1.4 0.4 0.0 3.3 5.0 0.1 0.0 0.0 0.0 0.2 1.2 0.1 0.0 4.7 0.0 4.8 0.0 10.1 7.0 3.1 0.0 1.5 0.0 3.4 0.0 0.1 2.2 0.7 0.0 1.6 0.6 0.1 1.4 0.1 0.0 0.0 0.3 0.3 0.0 0.3 ADH1A ADH1 ENSG00000187758 "Alcohol dehydrogenase 1A (class I), alpha polypeptide" P07327 4 99276369-99291003 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 306 "liver: 2739.1" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 200.9" "Cancer enriched" "Detected in some" 251 "liver cancer: 165.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 8.2" "CAB009562, HPA047814, HPA060902" Enhanced Approved "Plasma membrane,Cytosol" NA NA 38000000 "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "CAB009562: AB_2257984, HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.89e-2)" "unprognostic (6.16e-2)" "unprognostic (1.20e-1)" "unprognostic (2.07e-1)" "unprognostic (4.40e-1)" "prognostic favorable (2.38e-4)" "unprognostic (2.78e-3)" "unprognostic (4.25e-1)" "unprognostic (4.79e-3)" "unprognostic (6.21e-2)" "unprognostic (9.36e-2)" "unprognostic (3.25e-2)" "unprognostic (1.40e-1)" "unprognostic (2.86e-2)" 7.2 1.6 0.0 0.4 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.3 8.9 0.3 0.5 0.1 0.5 6.6 0.3 0.0 0.0 0.7 2739.1 0.8 0.0 0.1 0.1 0.1 1.1 0.0 0.3 0.1 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 1.8 0.0 0.1 0.3 0.4 0.3 0.0 0.0 0.1 1.0 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 15.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.1 0.1 0.3 0.0 10.7 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 8.6 200.9 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.3 0.2 0.1 0.0 0.0 0.5 0.0 0.0 0.0 ADH1B ADH2 ENSG00000196616 "Alcohol dehydrogenase 1B (class I), beta polypeptide" P00325 4 99304971-99352760 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 1501.5;liver: 5858.7" "Cell type enriched" "Detected in many" 6 "Hepatocytes: 4153.7" "Cancer enriched" "Detected in many" 31 "liver cancer: 223.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "ASC diff: 6574.3" "HPA047814, HPA060902" Supported Approved "Plasma membrane,Cytosol" NA NA 39000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (5.13e-2)" "unprognostic (9.80e-3)" "unprognostic (6.59e-2)" "unprognostic (5.56e-2)" "unprognostic (9.49e-2)" "unprognostic (5.53e-2)" "unprognostic (1.54e-3)" "unprognostic (1.04e-2)" "unprognostic (6.51e-2)" "unprognostic (2.73e-2)" "unprognostic (7.47e-3)" "unprognostic (7.79e-2)" "prognostic unfavorable (7.87e-4)" "unprognostic (4.60e-3)" "unprognostic (2.33e-1)" "unprognostic (2.58e-1)" "unprognostic (1.60e-2)" 1501.5 140.2 2.2 36.4 3.4 0.1 924.6 1.9 9.0 41.0 13.5 202.2 38.5 161.4 74.8 105.8 385.0 145.1 215.3 2.0 1.9 66.7 5858.7 373.2 25.8 4.7 2.2 117.7 49.1 7.8 24.2 6.8 3.2 26.7 114.7 0.1 67.9 26.7 66.6 159.2 237.1 73.4 4.4 72.7 141.1 2.8 2.2 19.8 94.5 228.2 16.0 287.9 118.7 2.4 0.0 0.0 0.0 0.0 6574.3 956.7 0.2 0.0 2.0 0.0 0.0 0.0 0.0 0.7 0.1 1.1 0.0 0.0 0.5 1.4 0.0 0.1 0.0 1.1 0.1 0.0 26.9 3.0 0.0 216.8 0.1 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.1 0.5 0.1 0.0 0.0 0.1 3.2 0.1 0.0 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.2 0.2 0.3 1.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 3.4 1.9 9.0 2.0 1.9 4.7 2.2 3.2 4.4 2.2 2.4 29.0 0.0 3.4 0.0 8.1 22.3 0.5 0.1 6.8 0.1 1.1 2.5 12.2 110.1 2.3 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.6 0.1 0.9 14.7 0.0 115.0 0.0 0.0 0.1 633.1 11.2 0.0 1.3 0.0 96.8 4153.7 0.1 0.0 0.0 0.0 0.0 98.8 25.4 0.6 55.3 3.5 28.4 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 7.1 0.7 0.0 0.1 0.2 0.1 6.6 15.0 47.9 0.0 0.1 10.4 13.1 0.1 8.9 0.1 0.0 0.2 ADH1C ADH3 ENSG00000248144 "Alcohol dehydrogenase 1C (class I), gamma polypeptide" P00326 4 99336497-99352746 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Oxidoreductase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 21 "intestine: 598.1;liver: 2062.2;stomach 1: 570.6" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 699.4;Gastric mucus-secreting cells: 611.2;Hepatocytes: 440.6;Undifferentiated cells: 420.5" "Cancer enriched" "Detected in many" 7 "liver cancer: 238.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.1;ASC TERT1: 3.6;HSkMC: 11.9;RPMI-8226: 2.1" "HPA047814, HPA060902" Supported Supported "Plasma membrane,Cytosol" NA NA 31000000 "Cluster 85: Liver - Metabolism" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA047814: AB_2680163, HPA060902: AB_2684384" "unprognostic (3.98e-2)" "unprognostic (9.88e-3)" "unprognostic (7.04e-2)" "unprognostic (1.90e-1)" "unprognostic (5.14e-1)" "unprognostic (1.57e-1)" "prognostic favorable (4.55e-4)" "prognostic favorable (2.99e-4)" "unprognostic (8.25e-2)" "unprognostic (8.89e-3)" "unprognostic (7.95e-2)" "unprognostic (2.04e-1)" "unprognostic (1.12e-1)" "unprognostic (1.21e-1)" "unprognostic (1.53e-1)" "unprognostic (1.70e-1)" "unprognostic (9.37e-2)" 22.9 0.8 0.1 29.8 0.1 0.0 19.2 0.1 0.1 4.7 0.0 329.5 598.1 5.1 7.2 5.1 5.8 51.6 5.9 0.1 0.0 19.6 2062.2 2.9 0.6 0.1 0.1 4.0 16.7 0.1 1.6 0.1 0.1 9.4 191.9 0.0 19.3 6.2 23.9 0.7 190.7 16.3 0.1 0.7 570.6 0.8 0.1 0.5 2.9 31.1 0.5 5.9 3.6 0.2 0.0 2.1 0.0 0.0 1.4 3.6 0.9 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.4 0.3 0.0 0.2 1.1 0.3 11.9 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 0.8 0.2 0.0 0.1 0.1 0.8 2.1 0.8 0.0 0.3 1.1 0.5 0.7 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.3 0.1 0.1 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 2.1 3.2 7.3 0.7 1.3 0.0 4.0 0.0 25.0 0.0 0.1 0.3 1.0 64.3 24.8 29.5 0.0 0.0 0.1 108.4 0.0 159.5 2.3 1.3 0.8 1.2 21.6 29.5 0.3 699.4 0.0 21.1 611.2 1.3 0.0 0.0 13.2 440.6 0.0 0.0 0.2 86.3 0.0 13.2 0.0 1.0 10.5 0.8 0.0 0.0 2.0 0.0 0.0 0.5 0.1 66.3 120.8 0.0 0.6 3.1 59.4 1.4 43.7 0.0 0.0 1.3 2.0 0.0 0.7 10.6 0.0 0.0 1.8 1.6 420.5 3.6 ADH7 ADH-4 ENSG00000196344 "Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide" P40394 4 99412261-99435737 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "esophagus: 196.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 89.0;Club cells: 64.1;Squamous epithelial cells: 209.1" "Cancer enhanced" "Detected in some" "cervical cancer: 18.4;head and neck cancer: 18.9;lung cancer: 22.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC TERT1: 1.0;HaCaT: 1.2" "Not detected" "Not detected" HPA039695 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "HPA039695: AB_10795681" "unprognostic (1.02e-2)" "unprognostic (8.64e-2)" "unprognostic (4.86e-2)" "unprognostic (5.66e-3)" "unprognostic (4.50e-2)" "unprognostic (1.66e-1)" "unprognostic (2.02e-1)" "unprognostic (1.88e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 196.3 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 22.8 0.0 0.0 0.7 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.2 0.0 0.0 38.1 0.3 4.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 89.0 21.1 0.0 0.0 0.0 0.2 0.0 64.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.0 0.1 7.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 18.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.2 0.6 0.0 0.0 26.2 0.0 0.0 0.0 2.3 0.0 0.0 209.1 0.0 0.0 0.0 0.0 0.0 1.0 ADSS2 ADSS ENSG00000035687 "Adenylosuccinate synthase 2" P30520 1 244408494-244451909 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 26.4;Cytotrophoblasts: 49.3;dendritic cells: 59.6;Extravillous trophoblasts: 97.2;Hofbauer cells: 35.8;Syncytiotrophoblasts: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA024400 Supported Approved "Plasma membrane,Cytosol" NA NA 690000 "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA024400: AB_1844623" "unprognostic (4.24e-3)" "unprognostic (2.63e-1)" "unprognostic (3.95e-2)" "unprognostic (8.68e-2)" "unprognostic (6.91e-2)" "unprognostic (2.04e-1)" "unprognostic (1.62e-2)" "unprognostic (2.58e-1)" "unprognostic (1.12e-1)" "unprognostic (1.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.10e-1)" "unprognostic (1.35e-1)" "unprognostic (7.62e-2)" "unprognostic (1.86e-1)" "unprognostic (2.04e-1)" "unprognostic (1.18e-2)" 19.8 20.5 17.8 28.1 22.0 43.9 34.6 21.7 26.7 25.9 17.0 28.7 28.7 23.4 29.8 32.6 23.9 21.0 8.9 19.2 21.1 32.9 24.3 25.3 31.9 21.9 19.6 21.7 19.8 27.6 14.5 28.6 23.1 25.3 29.8 11.4 22.8 25.6 10.8 33.2 27.1 25.2 19.6 23.7 35.0 70.3 20.9 33.8 34.9 8.4 34.9 36.2 21.5 28.7 89.9 48.6 41.6 36.9 47.6 67.8 76.2 88.5 74.4 62.3 47.0 64.6 84.5 79.7 57.1 68.9 26.6 66.1 45.9 58.0 69.5 59.6 81.0 53.1 47.8 49.3 57.1 127.1 65.6 46.8 68.5 58.1 58.3 72.1 225.6 43.3 94.0 57.7 62.7 21.6 82.3 85.0 110.5 85.0 53.1 74.9 39.4 86.5 103.8 55.2 56.2 49.2 75.2 69.0 91.4 43.9 48.0 66.7 99.4 57.1 31.3 67.0 93.7 69.1 97.2 60.0 47.2 146.8 86.3 48.3 22.8 20.0 20.4 29.9 22.0 15.3 18.6 17.8 20.1 12.3 15.6 17.9 17.5 23.6 33.6 7.9 22.3 18.8 17.8 22.0 21.7 26.7 19.2 21.1 21.9 19.6 23.1 19.6 20.9 28.7 26.4 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 0.0 0.0 0.0 0.0 49.3 59.6 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 97.2 9.3 0.0 0.0 0.0 0.0 0.0 0.0 35.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 54.0 11.0 0.0 0.0 0.0 AFAP1L2 "Em:AC005383.4, FLJ14564, KIAA1914, XB130" ENSG00000169129 "Actin filament associated protein 1 like 2" Q8N4X5 10 114294824-114404756 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 64.5;parathyroid gland: 68.7;thyroid gland: 82.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 40.5;Microglial cells: 34.7;Oligodendrocyte precursor cells: 122.6" "Cancer enhanced" "Detected in all" "thyroid cancer: 39.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 4 "B-cells: 1.6;T-cells: 1.8" "Cell line enhanced" "Detected in many" "A-431: 74.4;CAPAN-2: 77.4;EFO-21: 56.4;HaCaT: 98.7;RPMI-8226: 51.3;RPTEC TERT1: 59.7" "Low region specificity" "Detected in all" HPA037843 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane, Cytosol" "HPA037843: AB_10669990" "unprognostic (2.31e-3)" "unprognostic (1.30e-1)" "unprognostic (2.02e-1)" "unprognostic (5.06e-3)" "unprognostic (4.14e-2)" "unprognostic (9.80e-2)" "unprognostic (9.88e-2)" "unprognostic (1.08e-1)" "unprognostic (1.36e-1)" "unprognostic (1.32e-1)" "prognostic unfavorable (3.76e-4)" "unprognostic (2.08e-1)" "prognostic unfavorable (1.55e-5)" "unprognostic (1.11e-1)" "unprognostic (3.88e-2)" "unprognostic (1.72e-1)" "unprognostic (1.86e-1)" 7.6 2.4 15.7 4.2 12.9 0.1 10.2 21.5 13.1 21.8 5.9 13.0 3.9 23.9 13.2 9.3 22.9 4.5 4.7 11.8 12.4 17.6 1.7 5.3 4.3 12.9 12.8 15.1 11.9 68.7 2.4 18.4 13.6 13.1 5.1 3.7 6.9 23.9 3.0 9.8 6.4 18.9 13.6 64.5 5.9 1.4 13.3 13.5 82.2 4.4 7.6 5.9 14.7 13.5 74.4 10.8 10.0 0.1 0.0 0.0 0.0 0.0 0.5 0.4 0.4 0.1 77.4 0.1 56.4 0.6 1.1 98.7 0.2 27.2 0.2 1.5 0.1 0.0 0.7 0.0 3.0 0.0 2.7 0.0 28.9 8.1 7.1 0.3 0.3 2.8 0.0 0.2 0.0 3.1 1.9 0.1 0.5 2.0 0.5 0.9 0.8 51.3 59.7 0.6 0.3 0.5 2.3 1.7 2.9 16.0 0.0 0.1 0.0 0.0 0.4 0.0 0.4 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.0 0.5 0.0 1.1 1.6 1.1 1.2 0.0 1.6 0.3 0.9 0.1 0.4 0.0 0.1 1.8 0.6 15.7 12.9 21.5 13.1 11.8 12.4 12.9 12.8 13.6 13.6 13.3 13.5 14.6 0.0 0.0 0.7 1.2 12.4 7.3 3.1 5.2 0.8 1.8 5.3 2.2 0.0 1.8 40.5 0.0 1.5 2.4 8.1 0.0 0.6 1.0 5.3 7.4 14.5 0.0 0.8 6.5 14.3 1.2 10.7 3.1 9.5 0.0 0.3 13.2 0.0 0.5 1.7 10.1 1.8 0.0 0.0 3.7 3.0 3.1 0.5 5.4 34.7 0.6 3.2 0.0 122.6 0.6 23.2 1.7 1.9 0.1 3.7 2.2 0.4 1.5 0.6 19.7 21.4 24.7 0.0 0.8 2.3 6.8 0.3 3.4 2.4 2.2 4.3 AFG1L "AFG1, LACE1" ENSG00000135537 "AFG1 like ATPase" Q8WV93 6 108294991-108526796 "Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 6.4;Distal tubular cells: 9.8;Hofbauer cells: 5.7;Proximal tubular cells: 6.3;Respiratory ciliated cells: 5.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030154, HPA030155, HPA030659" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 43: THP-1 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA030154: AB_10600769, HPA030155: AB_10601232, HPA030659: AB_10602415" "unprognostic (9.76e-5)" "unprognostic (1.72e-1)" "unprognostic (1.68e-1)" "unprognostic (3.76e-2)" "unprognostic (1.62e-1)" "unprognostic (7.04e-2)" "unprognostic (2.57e-1)" "unprognostic (5.53e-2)" "unprognostic (2.35e-3)" "unprognostic (1.48e-1)" "unprognostic (2.73e-2)" "unprognostic (9.61e-2)" "unprognostic (8.40e-8)" "unprognostic (2.03e-2)" "unprognostic (2.03e-1)" "unprognostic (1.41e-1)" "unprognostic (1.23e-1)" 1.8 2.1 2.2 1.3 2.7 2.1 2.2 2.0 3.3 1.7 2.7 2.6 4.2 1.5 1.9 1.6 2.2 1.5 4.6 1.7 1.9 5.0 3.7 1.7 1.8 1.8 2.0 1.7 2.1 5.4 1.5 2.2 2.0 1.6 3.1 3.1 1.8 1.7 3.7 1.2 3.0 1.7 1.7 2.0 2.8 10.7 2.7 2.3 3.0 4.0 2.1 1.7 1.1 3.2 2.7 1.4 3.4 6.1 3.5 5.1 3.3 3.0 4.4 4.8 4.7 5.7 3.3 4.8 3.8 4.7 5.8 1.5 4.4 4.5 5.4 2.8 2.6 5.7 1.8 6.6 3.5 5.3 2.7 4.7 3.6 3.6 5.8 3.1 2.6 3.5 5.9 2.2 4.5 2.6 0.9 4.8 2.2 4.6 2.8 3.3 4.6 2.8 6.1 2.9 3.7 3.2 2.4 3.5 6.4 4.5 2.8 9.8 3.2 2.9 0.7 2.6 3.4 1.5 2.6 3.7 3.6 6.0 4.5 0.0 1.6 2.8 1.0 1.2 1.3 2.5 1.5 1.9 1.4 3.4 2.1 1.4 0.4 2.4 4.3 1.6 2.3 0.7 2.2 2.7 2.0 3.3 1.7 1.9 1.8 2.0 2.0 1.7 2.7 3.2 2.4 0.0 4.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 2.0 2.2 0.0 0.0 5.0 3.7 0.0 6.4 1.1 0.0 9.8 3.1 0.0 2.6 2.6 2.2 0.0 0.0 0.0 3.8 4.6 1.2 0.0 1.8 2.5 5.1 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.4 0.0 0.0 6.3 5.8 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 5.2 0.9 4.5 0.0 0.0 AGRN AGRIN ENSG00000188157 Agrin O00468 1 1020120-1056118 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" Differentiation "Developmental protein" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 94.5;Collecting duct cells: 156.3;Ductal cells: 91.2;Pancreatic endocrine cells: 87.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 205.3;EFO-21: 236.9;HaCaT: 210.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040090 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 20000000 "Cluster 7: Kidney - Transmembrane transport" "Cluster 38: EFO-21 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA040090: AB_10805603" "unprognostic (8.04e-2)" "unprognostic (8.25e-3)" "unprognostic (1.42e-3)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (2.41e-2)" "prognostic unfavorable (4.62e-4)" "unprognostic (2.82e-3)" "unprognostic (1.32e-1)" "unprognostic (3.33e-2)" "unprognostic (9.49e-3)" "unprognostic (1.06e-1)" "unprognostic (8.46e-2)" "unprognostic (8.49e-2)" "unprognostic (2.07e-2)" "unprognostic (4.08e-1)" "unprognostic (1.31e-2)" 11.4 2.7 8.7 4.3 5.5 2.0 14.7 0.1 13.9 14.4 8.9 10.9 7.9 13.7 1.8 15.6 14.6 7.3 9.9 5.8 0.0 44.0 13.3 19.8 1.6 16.0 1.4 5.5 28.0 3.9 8.3 5.1 6.1 14.4 1.5 0.8 24.8 8.2 4.2 16.5 9.6 2.9 2.2 6.3 13.4 9.7 7.9 2.6 34.7 2.0 1.6 16.2 11.6 9.9 124.3 75.1 11.1 42.7 2.4 3.0 122.1 61.4 19.6 39.7 24.5 60.6 205.3 2.3 236.9 9.6 19.3 210.1 4.1 75.6 4.7 4.4 28.6 0.2 102.1 54.2 17.1 1.8 23.1 10.5 32.2 12.6 27.7 55.9 7.2 1.7 25.7 0.7 3.5 93.0 0.8 17.6 28.4 39.7 54.5 20.1 27.0 18.5 70.0 51.4 2.4 25.9 124.8 129.1 121.9 12.7 114.8 7.4 107.8 47.7 169.0 6.4 50.6 1.2 0.6 3.5 30.4 10.8 13.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 5.5 0.1 13.9 5.8 0.0 16.0 1.4 6.1 2.2 7.9 9.9 27.4 25.6 8.8 15.0 2.2 15.0 9.2 94.5 19.9 1.4 32.7 39.2 3.1 61.5 42.0 156.3 8.4 1.6 0.9 29.9 1.9 91.2 0.4 37.2 14.0 29.0 6.7 1.7 23.1 16.9 4.8 8.7 17.9 62.7 2.5 7.2 21.8 13.1 4.1 5.0 7.8 11.6 36.7 2.9 10.1 1.0 5.6 4.3 24.9 12.2 15.6 10.5 0.0 15.1 29.6 87.3 17.7 2.6 0.6 22.3 18.1 16.0 33.0 5.3 6.6 3.3 23.3 0.8 11.4 11.7 6.0 1.2 2.9 2.3 18.3 21.2 AHNAK MGC5395 ENSG00000124942 "AHNAK nucleoprotein" Q09666 11 62433542-62556235 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 561.4;fHDF/TERT166: 554.5;TIME: 582.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 395.4" "HPA019010, HPA019070, HPA026643" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 10000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 31: Skin - Epidermis development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA019010: AB_1844657, HPA019070: AB_1844656, HPA026643: AB_10670426" "unprognostic (1.39e-1)" "unprognostic (7.84e-2)" "unprognostic (3.46e-1)" "unprognostic (3.19e-1)" "unprognostic (1.96e-2)" "unprognostic (5.99e-2)" "unprognostic (2.53e-1)" "unprognostic (1.63e-2)" "unprognostic (4.84e-2)" "unprognostic (1.98e-3)" "prognostic unfavorable (2.42e-4)" "unprognostic (4.30e-1)" "unprognostic (4.49e-3)" "unprognostic (5.42e-2)" "unprognostic (1.18e-1)" "unprognostic (2.61e-1)" "prognostic unfavorable (3.47e-6)" 243.1 27.9 62.6 43.4 50.2 44.1 190.3 33.7 45.4 183.3 61.0 276.2 49.0 183.3 51.7 248.2 145.5 74.8 115.1 65.0 98.0 59.7 60.1 144.1 36.7 76.2 48.3 125.8 30.3 26.3 16.9 97.3 62.9 88.5 96.6 10.1 127.5 105.7 188.5 334.7 136.6 113.1 60.8 59.5 133.5 18.0 49.0 27.9 64.9 172.2 63.7 142.0 213.3 78.4 188.2 107.9 9.8 44.1 421.8 561.4 70.3 166.0 201.4 103.0 57.4 93.7 64.9 0.2 61.7 554.5 79.8 244.1 41.2 203.7 130.7 154.2 7.3 22.6 173.4 27.9 80.8 31.5 142.2 204.2 233.0 202.4 183.6 131.5 215.4 2.7 21.8 138.8 211.7 72.1 0.4 60.7 3.0 59.6 171.7 0.4 45.1 113.9 227.1 120.2 0.3 9.2 167.5 69.3 69.0 198.8 133.7 28.4 582.1 182.4 119.8 229.8 74.4 25.0 5.4 0.6 138.2 10.1 60.9 44.1 75.6 0.3 38.7 45.0 25.8 20.0 24.8 31.7 73.8 16.1 3.2 17.3 1.1 31.5 37.8 20.2 21.5 36.8 62.6 50.2 33.7 45.4 65.0 98.0 76.2 48.3 62.9 60.8 49.0 78.4 413.1 439.1 106.3 49.3 171.4 479.4 133.8 285.0 253.2 1.4 173.0 226.8 199.9 195.9 224.1 193.1 0.0 110.8 194.3 400.8 13.7 99.6 10.6 188.5 195.0 282.5 47.6 43.7 0.9 64.1 145.6 312.9 538.2 351.2 238.9 4.3 201.4 88.5 79.4 1.7 0.8 164.8 138.4 329.8 458.3 33.2 451.4 292.3 318.4 43.1 284.8 30.7 138.0 0.5 0.4 262.5 195.5 466.0 329.0 202.4 262.3 6.8 149.3 1.2 177.5 349.5 244.4 3.1 8.1 596.4 610.3 102.2 256.5 3.0 101.8 198.0 AHNAK2 C14orf78 ENSG00000185567 "AHNAK nucleoprotein 2" Q8IVF2 14 104937244-104978374 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 305.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 114.3;Basal respiratory cells: 83.8;Horizontal cells: 60.6;Ionocytes: 61.1;Pancreatic endocrine cells: 68.2;Respiratory ciliated cells: 66.8;Squamous epithelial cells: 63.7;Suprabasal keratinocytes: 164.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 24.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 135.1;HBEC3-KT: 124.9;hTCEpi: 308.7;hTERT-HME1: 130.3;TIME: 138.4" "Low region specificity" "Detected in single" "Group enriched" "Detected in many" 7 "medulla oblongata: 11.3;midbrain: 10.6;pons: 13.2;spinal cord: 38.9;thalamus: 15.0" "HPA000878, HPA002940, HPA004145, HPA020111" Enhanced Enhanced "Plasma membrane,Cytosol" No No 40000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA000878: AB_2666127, HPA002940: AB_1859547, HPA004145: AB_1859546, HPA020111: AB_2670371" "unprognostic (3.56e-1)" "unprognostic (6.04e-2)" "unprognostic (6.19e-3)" "unprognostic (1.31e-3)" "unprognostic (9.55e-4)" "unprognostic (1.76e-1)" "unprognostic (1.36e-1)" "prognostic unfavorable (2.79e-5)" "unprognostic (3.43e-1)" "unprognostic (3.06e-3)" "prognostic unfavorable (4.05e-6)" "unprognostic (1.48e-1)" "unprognostic (1.17e-2)" "unprognostic (1.39e-2)" "unprognostic (6.97e-2)" "unprognostic (2.05e-1)" "prognostic unfavorable (2.23e-5)" 30.4 2.3 9.8 2.4 9.9 0.0 16.4 9.3 15.9 84.5 4.6 105.3 1.4 64.3 2.9 114.1 29.2 5.1 4.5 9.7 16.0 3.5 6.2 5.1 0.1 38.1 15.3 3.5 1.6 0.7 3.4 1.8 40.8 18.6 8.6 19.0 24.0 28.6 3.6 305.9 20.2 31.6 12.4 0.9 25.2 7.7 18.1 0.4 2.8 4.5 4.7 49.4 86.6 18.5 2.9 107.6 0.1 6.0 120.0 135.1 0.2 10.5 22.3 3.8 1.9 0.3 38.9 0.1 14.5 82.9 85.3 62.9 0.3 124.9 1.7 0.0 0.4 0.0 67.5 0.5 11.0 0.0 3.8 17.6 308.7 12.1 130.3 52.3 54.7 0.0 0.0 0.2 62.8 8.0 0.0 0.0 0.3 9.5 42.9 0.3 5.7 0.1 84.4 0.0 0.6 0.6 46.2 0.1 2.3 2.8 6.0 0.0 138.4 29.3 17.9 33.8 9.9 0.0 0.0 0.0 88.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 9.8 9.9 9.3 15.9 9.7 16.0 38.1 15.3 40.8 12.4 18.1 18.5 3.8 12.8 1.1 0.3 0.0 114.3 4.9 83.8 13.1 8.9 2.2 1.3 1.5 0.0 38.2 1.8 2.1 0.2 0.3 0.4 0.0 11.9 24.2 16.0 10.5 13.0 0.0 0.0 8.2 8.7 0.5 31.9 0.0 18.9 17.1 0.1 3.6 2.1 1.0 60.6 5.1 0.0 61.1 0.3 12.7 3.1 0.6 0.7 32.0 3.7 0.0 3.2 0.0 1.5 3.3 68.2 0.0 0.4 0.0 4.5 0.0 0.3 66.8 13.9 0.0 13.1 8.6 0.4 4.3 63.7 164.7 0.1 0.9 0.1 0.2 6.2 AKAP10 "D-AKAP2, MGC9414, PRKA10" ENSG00000108599 "A-kinase anchoring protein 10" O43572 17 19904302-19978343 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 78.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SuSa: 84.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028901 Approved Supported "Plasma membrane,Cytosol" Yes No "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA028901: AB_10602227" "unprognostic (2.17e-2)" "unprognostic (3.48e-2)" "unprognostic (5.33e-1)" "unprognostic (1.40e-1)" "unprognostic (1.50e-1)" "unprognostic (5.51e-2)" "unprognostic (1.59e-3)" "unprognostic (3.88e-1)" "unprognostic (7.69e-3)" "unprognostic (1.89e-1)" "unprognostic (3.59e-2)" "unprognostic (3.21e-2)" "unprognostic (3.21e-2)" "unprognostic (2.49e-2)" "unprognostic (7.15e-2)" "unprognostic (2.16e-2)" "unprognostic (5.20e-2)" 11.4 13.3 10.5 12.3 12.4 10.6 12.3 11.4 13.6 11.5 15.1 11.4 9.5 12.4 8.8 10.6 10.4 10.7 7.4 11.3 11.6 13.1 8.1 11.0 16.0 9.9 10.7 13.5 8.4 15.1 7.5 12.2 10.6 10.9 11.6 15.3 9.8 11.7 7.2 9.5 10.1 13.3 10.4 14.9 11.1 14.2 13.8 14.1 15.1 9.4 12.5 11.3 10.2 14.7 18.1 21.3 13.9 9.7 18.0 22.5 25.7 20.6 21.9 22.4 26.7 23.2 10.6 15.4 13.6 16.4 19.4 18.8 18.1 17.2 30.4 12.8 15.4 13.2 20.2 11.4 17.0 9.7 20.7 19.1 21.1 20.5 25.1 25.0 18.3 18.5 8.6 7.5 23.6 13.1 18.1 14.3 9.1 25.1 7.2 11.8 45.5 8.1 18.7 11.3 4.7 14.1 23.6 11.0 19.7 84.8 26.7 10.7 16.1 17.2 14.2 14.8 19.3 9.3 10.7 18.8 22.8 11.5 17.0 4.9 9.7 12.6 8.6 14.4 8.0 8.4 8.4 9.4 8.5 9.2 10.0 8.9 33.8 7.6 13.9 6.3 7.1 4.3 10.5 12.4 11.4 13.6 11.3 11.6 9.9 10.7 10.6 10.4 13.8 14.7 13.4 3.2 12.3 71.2 24.4 7.0 9.7 8.9 10.2 24.6 11.1 9.0 8.4 21.5 11.9 5.5 16.7 14.9 16.8 15.8 1.9 9.9 12.8 11.0 14.8 12.6 7.2 15.2 55.1 7.2 11.1 11.7 14.8 10.8 10.1 18.0 16.8 13.6 16.5 33.7 54.6 9.9 12.2 35.1 10.5 13.9 15.2 21.4 5.4 61.8 32.3 11.7 25.7 51.8 78.5 7.9 15.2 13.9 11.2 15.6 14.6 5.7 15.3 23.2 19.7 10.5 11.2 23.1 23.6 11.0 7.7 14.0 19.0 15.6 11.8 12.1 AKAP12 "AKAP250, SSeCKS" ENSG00000131016 "A-kinase anchoring protein 12" Q02952 6 151239967-151358559 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 352.6;Endothelial cells: 278.4;Fibroblasts: 270.0;Muller glia cells: 583.0;Pancreatic endocrine cells: 322.1;Spermatocytes: 325.4" "Cancer enhanced" "Detected in all" "testis cancer: 39.5" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 235 "basophil: 37.2" "Lineage enriched" "Detected in single" 235 "granulocytes: 37.2" "Cell line enhanced" "Detected in many" "REH: 193.0;TIME: 188.2;U-251 MG: 202.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006344, CAB026379, HPA056230" Enhanced Enhanced "Plasma membrane,Cytosol" No No 10000000 "Cluster 38: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB026379: , HPA006344: AB_1078118, HPA056230: AB_2683073" "unprognostic (6.66e-2)" "unprognostic (1.51e-1)" "unprognostic (9.90e-3)" "prognostic unfavorable (7.08e-4)" "unprognostic (2.61e-2)" "unprognostic (8.88e-2)" "unprognostic (5.05e-2)" "prognostic unfavorable (6.34e-5)" "unprognostic (1.34e-1)" "unprognostic (8.26e-3)" "unprognostic (2.59e-1)" "unprognostic (4.72e-2)" "unprognostic (4.51e-3)" "unprognostic (1.10e-3)" "unprognostic (3.51e-1)" "unprognostic (7.03e-3)" "unprognostic (2.34e-2)" 105.6 16.0 13.8 17.1 16.6 2.2 59.7 99.7 57.5 19.8 4.5 60.1 8.6 31.1 9.3 18.6 31.2 31.5 51.8 14.7 66.8 35.8 30.6 44.3 6.9 67.0 35.3 87.8 10.8 1.6 23.3 38.3 74.7 23.1 13.2 109.4 6.5 20.8 11.9 9.4 24.9 42.9 10.9 14.3 25.6 100.0 39.4 5.9 22.1 14.5 3.4 33.0 21.2 24.3 7.8 37.8 53.2 0.1 98.2 145.9 18.8 43.9 23.7 19.3 19.4 0.9 141.6 0.0 17.1 33.2 160.4 1.0 102.2 32.5 17.2 50.2 37.6 0.6 40.8 35.6 10.9 0.0 9.6 104.0 0.0 81.9 4.3 25.4 127.8 0.6 9.8 0.9 70.7 0.5 0.3 0.1 33.3 0.1 43.9 193.0 2.3 0.2 110.2 6.3 37.9 22.0 14.1 0.5 24.9 74.6 2.8 0.5 188.2 2.6 34.0 110.4 202.9 0.4 0.1 0.2 63.2 0.1 37.4 37.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.8 16.6 99.7 57.5 14.7 66.8 67.0 35.3 74.7 10.9 39.4 24.3 352.6 12.8 16.2 34.3 6.8 19.6 19.6 63.2 1.2 14.5 1.2 3.9 12.1 5.7 31.1 51.5 2.1 2.4 0.9 1.2 1.9 107.0 101.4 14.2 195.4 278.4 1.8 3.2 75.8 6.7 10.1 270.0 3.6 31.6 64.2 14.7 194.5 4.8 26.9 0.0 33.3 0.7 4.1 15.7 45.4 116.3 39.7 13.9 58.7 37.5 0.6 583.0 1.0 59.8 5.1 322.1 1.1 110.6 6.7 49.5 0.0 89.4 6.0 31.0 98.6 208.3 243.0 325.4 33.0 1.6 11.4 10.0 5.1 9.3 2.5 105.3 AKR1B10 "AKR1B11, AKR1B12, ALDRLn, ARL-1, ARL1, HIS, HSI" ENSG00000198074 "Aldo-keto reductase family 1 member B10" O60218 7 134527567-134541412 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted secreted proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 224.5;intestine: 614.8;stomach 1: 432.5" "Cell type enhanced" "Detected in many" "Cholangiocytes: 193.0;Distal enterocytes: 201.0;Gastric mucus-secreting cells: 542.3;Proximal enterocytes: 327.1" "Cancer enhanced" "Detected in many" "liver cancer: 353.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 104 "A549: 2959.1;Hep G2: 835.6;OE19: 3141.0" "Low region specificity" "Detected in all" "HPA020280, CAB070163, HPA073633" Enhanced Supported "Plasma membrane,Cytosol" "Secreted to digestive system" NA NA 67000000 "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "CAB070163: AB_10008614, HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (1.29e-2)" "unprognostic (1.50e-1)" "prognostic favorable (1.91e-4)" "unprognostic (6.03e-2)" "unprognostic (4.67e-2)" "unprognostic (2.57e-1)" "unprognostic (2.16e-3)" "unprognostic (1.01e-1)" "unprognostic (1.47e-1)" "unprognostic (3.18e-2)" "unprognostic (4.65e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (4.80e-9)" "unprognostic (2.12e-1)" "unprognostic (2.12e-1)" "unprognostic (1.43e-2)" "unprognostic (1.25e-1)" 0.9 5.5 0.1 7.9 0.0 0.2 0.4 0.3 0.1 73.9 0.0 73.4 614.8 0.5 0.1 224.5 0.9 176.1 0.2 0.1 0.1 12.2 40.0 0.4 0.3 0.0 0.0 0.2 0.7 0.0 4.8 0.1 0.1 1.3 45.6 0.1 32.4 0.2 3.7 7.7 354.8 3.2 0.1 0.1 432.5 0.6 0.0 5.5 0.6 5.9 7.7 65.8 145.6 0.2 0.0 2959.1 0.0 0.0 0.7 2.3 9.0 0.3 1.1 0.2 0.0 5.9 0.9 0.0 1.1 1.6 4.6 6.2 0.0 4.0 0.2 0.1 0.0 0.0 1.9 835.6 0.7 0.0 0.6 0.1 13.8 0.7 0.0 4.0 0.5 0.0 0.0 0.0 0.6 5.4 0.1 1.3 0.5 3141.0 2.3 0.3 0.0 2.7 1.5 2.7 1.0 1.5 1.8 1.3 0.1 0.1 0.0 0.1 1.9 1.2 1.2 0.2 1.0 0.4 0.1 0.0 22.2 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.0 0.0 1.0 2.8 2.1 52.1 3.4 0.0 0.1 0.0 0.7 193.0 13.5 0.0 0.0 0.3 0.0 201.0 0.0 31.5 0.7 2.9 0.1 0.2 3.5 2.7 0.0 27.5 0.1 4.4 542.3 1.0 0.0 0.0 2.2 62.9 0.0 0.0 0.1 29.5 4.1 0.6 0.3 0.7 3.4 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 66.9 42.5 1.9 1.7 1.0 327.1 3.8 4.8 0.0 0.0 3.7 1.5 0.0 0.1 96.0 10.4 0.3 0.5 0.0 73.0 11.4 AKR1B15 ENSG00000227471 "Aldo-keto reductase family 1 member B15" C9JRZ8 7 134549110-134579875 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "breast: 166.7" "Cell type enhanced" "Detected in some" "Early spermatids: 2.2;Fibroblasts: 2.9;Late spermatids: 3.6;Skeletal myocytes: 12.5;Syncytiotrophoblasts: 10.4" "Cancer enhanced" "Detected in many" "head and neck cancer: 5.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 15.8;HDLM-2: 12.8;Hep G2: 11.2;SK-BR-3: 5.1;U-87 MG: 6.7" "HPA020280, HPA073633" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 5: Breast - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA020280: AB_10602228, HPA073633: AB_2686620" "unprognostic (2.35e-1)" "unprognostic (3.85e-2)" "unprognostic (9.74e-3)" "unprognostic (2.74e-2)" "unprognostic (2.08e-1)" "prognostic favorable (8.36e-4)" "prognostic unfavorable (1.80e-5)" "unprognostic (5.04e-2)" "unprognostic (2.39e-1)" "unprognostic (2.75e-1)" "unprognostic (2.14e-3)" "unprognostic (1.24e-1)" "unprognostic (1.22e-7)" "unprognostic (6.88e-2)" "unprognostic (4.29e-1)" "unprognostic (2.99e-3)" "prognostic unfavorable (1.90e-5)" 0.4 0.1 0.4 0.2 1.4 0.0 166.7 0.3 0.5 1.1 0.0 0.8 14.0 0.0 0.2 3.2 0.0 5.2 0.1 0.4 1.1 0.1 2.1 0.0 0.0 0.6 1.1 0.0 0.0 0.0 0.0 0.8 0.6 0.3 0.6 0.3 1.8 0.0 7.8 1.1 4.5 0.0 0.7 0.0 12.0 0.5 1.4 0.2 0.1 18.8 0.3 0.9 2.6 1.5 0.1 15.8 0.1 0.0 0.6 0.5 0.9 0.0 0.4 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.7 0.1 0.0 0.1 0.0 12.8 0.0 0.1 0.2 11.2 0.0 0.2 0.5 0.0 0.2 0.0 0.1 0.1 0.0 0.1 0.2 0.5 0.0 0.0 0.2 0.2 3.1 0.4 0.0 0.1 0.2 0.3 0.1 0.1 0.1 0.1 0.6 5.1 0.0 0.1 0.0 0.3 0.0 0.1 0.7 0.3 0.0 0.2 0.2 0.2 6.7 0.2 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.4 0.3 0.5 0.4 1.1 0.6 1.1 0.6 0.7 1.4 1.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.8 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.9 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.4 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.5 0.1 0.0 0.7 0.0 0.3 10.4 0.1 0.0 0.0 0.1 AL353671.1 ENSG00000288684 "Novel protein" 9 32455323-32552603 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "neutrophil: 5.4" "Lineage enriched" "Detected in single" 7 "granulocytes: 5.4" "Low cell line specificity" "Detected in some" "HPA047193, HPA073217" Uncertain Approved "Plasma membrane,Cytosol" No NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 36: HEL - Hemostasis" "Plasma membrane, Cytosol" "HPA047193: AB_2679978, HPA073217: " 0.7 0.1 0.5 0.3 0.5 0.2 0.2 0.4 0.5 0.4 0.5 0.3 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.3 0.6 0.3 0.5 0.2 0.0 0.9 0.9 0.1 0.0 0.8 0.1 0.9 0.2 0.2 0.0 0.2 0.4 0.4 0.2 0.3 0.2 0.5 0.2 0.2 0.1 0.8 0.5 0.1 0.5 0.1 0.2 0.9 0.3 0.5 0.6 0.1 0.8 0.7 0.2 1.4 0.7 0.7 1.4 0.7 0.0 0.4 0.2 0.6 0.9 0.1 0.2 0.7 0.0 1.3 0.4 1.8 0.7 0.0 0.4 0.8 0.1 0.7 0.5 0.6 1.0 0.8 1.1 1.3 0.2 0.1 0.7 0.0 0.3 0.7 0.3 0.9 0.1 1.4 0.3 0.1 0.3 0.7 0.6 1.4 0.5 0.2 0.2 0.1 0.1 0.0 0.5 0.6 0.5 0.6 0.4 0.3 0.5 0.4 0.4 0.2 0.0 1.7 0.4 1.6 0.5 0.4 0.3 0.5 0.5 0.6 0.3 0.3 0.6 0.5 5.4 0.4 0.3 0.1 0.8 0.3 0.5 0.5 0.4 0.5 0.3 0.6 0.9 0.9 0.9 0.5 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ALOX15B 15-LOX-2 ENSG00000179593 "Arachidonate 15-lipoxygenase type B" O15296 17 8039034-8049134 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "breast: 111.7;prostate: 73.1" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 75.8;Basal respiratory cells: 22.0;Kupffer cells: 42.2;monocytes: 87.9;Prostatic glandular cells: 25.6;Squamous epithelial cells: 44.4" "Cancer enriched" "Detected in all" 5 "prostate cancer: 91.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 8 "classical monocyte: 3.9;myeloid DC: 4.3" "Group enriched" "Detected in many" 8 "dendritic cells: 4.3;monocytes: 3.9" "Cell line enhanced" "Detected in some" "HHSteC: 7.7;HSkMC: 16.6;hTCEpi: 35.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA010562 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytosol" "HPA010562: AB_2668305" "unprognostic (1.76e-2)" "unprognostic (6.47e-2)" "unprognostic (2.56e-1)" "unprognostic (2.28e-3)" "unprognostic (1.67e-2)" "unprognostic (1.52e-1)" "unprognostic (1.34e-1)" "unprognostic (1.52e-1)" "unprognostic (2.28e-1)" "unprognostic (1.85e-1)" "unprognostic (1.44e-2)" "unprognostic (4.59e-1)" "unprognostic (1.59e-2)" "unprognostic (9.37e-2)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" "unprognostic (9.49e-2)" 2.2 1.7 0.7 1.3 0.7 0.4 111.7 0.6 2.5 12.0 0.5 2.3 0.1 1.1 0.9 39.1 1.6 0.7 0.7 0.7 0.8 0.5 0.4 24.5 2.9 1.8 0.9 0.7 1.4 0.2 0.5 1.2 1.6 73.1 0.3 0.3 3.7 0.1 0.3 36.9 3.7 0.1 0.9 3.8 4.4 0.5 0.9 0.7 1.9 0.1 7.6 1.7 33.4 1.9 0.1 0.0 0.0 0.1 0.5 0.7 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.0 16.6 35.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.2 0.5 0.0 0.1 0.0 0.9 0.7 0.7 0.6 2.5 0.7 0.8 1.8 0.9 1.6 0.9 0.9 1.9 1.4 0.0 75.8 0.0 0.3 3.1 0.6 22.0 7.4 0.0 19.8 12.3 0.3 1.5 8.2 0.0 0.0 0.2 0.2 0.2 0.0 0.1 1.3 0.0 0.8 0.4 0.0 0.0 0.2 0.4 0.0 0.2 0.0 0.2 1.3 0.0 0.7 0.3 4.2 0.0 0.0 0.0 2.0 42.2 1.1 0.8 0.0 15.4 5.4 0.0 87.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.4 25.6 0.0 0.0 2.2 0.0 0.0 0.1 1.3 0.6 0.8 44.4 1.1 0.8 0.0 0.0 0.0 2.2 ALOXE3 "E-LOX, eLOX3" ENSG00000179148 "Arachidonate lipoxygenase 3" Q9BYJ1 17 8095900-8119047 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism" "Dioxygenase, Isomerase, Lyase, Oxidoreductase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 27 "skin 1: 56.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.1;Pancreatic endocrine cells: 6.3;Prostatic glandular cells: 1.8;Spermatocytes: 1.8;Spermatogonia: 1.7;Suprabasal keratinocytes: 1.8" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 3.9;melanoma: 1.5" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 6.4;HBEC3-KT: 10.1;hTCEpi: 7.3;hTERT-HME1: 13.7;T-47d: 4.4" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA023120, HPA078597" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 61: Skin - Cornification" "Cluster 30: Epithelial cell lines - Translation" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA023120: AB_10959300, HPA078597: AB_2732385" "unprognostic (2.40e-1)" "unprognostic (3.01e-2)" "unprognostic (1.87e-3)" "unprognostic (2.09e-4)" "unprognostic (1.07e-2)" "unprognostic (4.06e-2)" "unprognostic (3.56e-4)" "unprognostic (3.60e-1)" "unprognostic (4.65e-2)" "unprognostic (3.82e-2)" "unprognostic (3.72e-1)" "unprognostic (3.66e-5)" "unprognostic (9.81e-2)" "unprognostic (2.55e-1)" "unprognostic (1.08e-2)" "unprognostic (2.88e-2)" 0.0 0.0 0.5 0.0 0.3 0.0 1.6 1.9 2.1 0.6 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.7 0.4 0.0 0.0 0.0 0.0 0.8 0.7 0.0 0.1 0.4 0.2 0.1 0.7 0.1 0.0 0.1 0.3 0.0 0.1 56.2 0.0 0.0 0.1 0.0 0.0 0.8 1.0 0.0 0.0 0.0 1.2 0.0 1.8 0.5 6.4 0.7 0.0 0.0 0.0 0.0 0.0 0.4 0.4 0.0 0.4 0.1 0.5 0.2 0.2 0.1 2.9 0.4 0.8 10.1 0.1 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.3 0.1 13.7 0.0 0.0 0.9 0.0 0.1 0.0 2.3 0.0 0.0 0.0 0.2 2.0 0.0 0.0 0.0 0.1 0.3 0.0 0.1 0.0 0.7 0.0 0.0 4.4 0.0 0.1 0.0 2.1 0.0 0.3 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 1.9 2.1 0.7 0.4 0.8 0.7 0.7 0.1 1.0 0.5 0.1 0.0 0.0 0.0 0.0 0.3 2.1 1.2 0.0 0.0 0.6 0.5 0.5 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.4 0.4 0.1 0.1 0.2 0.0 0.0 1.2 0.9 1.2 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.2 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.3 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.8 1.7 0.3 1.8 1.1 0.0 0.0 0.0 0.6 AMACR "P504S, RACE" ENSG00000242110 "Alpha-methylacyl-CoA racemase" Q9UHK6 5 33986165-34008104 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Disease variant, Intrahepatic cholestasis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 134.3;liver: 180.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.7;Hepatocytes: 21.6;Late spermatids: 21.6;Proximal tubular cells: 38.5" "Group enriched" "Detected in all" 4 "liver cancer: 8.8;prostate cancer: 34.5;renal cancer: 14.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-266/70: 175.4;U-266/84: 98.0" "Low region specificity" "Detected in all" "CAB001809, HPA019527, HPA020912" Enhanced Supported "Vesicles,Plasma membrane" NA NA 70000 "Cluster 14: Monocytes - Unknown function" "Cluster 81: Kidney & Liver - Metabolism" "Cluster 29: U-266 - Adaptive immune response" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "CAB001809: AB_2305454, HPA019527: AB_10669651, HPA020912: AB_10670034" "unprognostic (8.96e-2)" "unprognostic (5.20e-3)" "prognostic favorable (7.11e-4)" "unprognostic (9.55e-2)" "unprognostic (1.39e-1)" "unprognostic (9.12e-3)" "unprognostic (1.68e-1)" "unprognostic (5.41e-2)" "unprognostic (1.50e-1)" "unprognostic (1.60e-1)" "unprognostic (5.59e-5)" "unprognostic (1.95e-2)" "unprognostic (5.52e-3)" "unprognostic (6.32e-2)" "unprognostic (3.41e-1)" "unprognostic (2.18e-1)" "unprognostic (1.50e-1)" 8.6 15.0 5.9 5.0 5.5 3.0 6.4 4.6 6.0 6.5 4.6 40.0 18.0 4.7 9.6 15.6 6.2 20.5 10.1 5.4 7.8 134.3 180.6 9.2 3.6 5.9 6.4 7.8 13.8 13.0 5.7 7.7 6.6 39.3 42.9 12.0 60.7 12.5 19.2 4.9 15.9 7.0 5.8 5.4 34.8 4.3 8.4 4.8 8.3 14.9 5.6 8.8 8.5 5.8 12.7 20.2 11.1 14.3 7.7 11.9 19.1 16.6 12.2 7.6 5.7 66.1 15.1 4.1 8.7 23.6 28.6 5.8 2.8 12.0 7.7 12.7 10.9 9.8 13.7 19.0 5.4 6.0 3.0 18.1 6.0 9.7 3.6 10.7 8.5 8.3 3.8 14.7 22.4 9.6 5.0 7.6 10.0 9.4 32.9 6.0 18.6 6.5 33.2 62.4 6.1 8.7 27.6 19.3 16.9 9.1 14.9 5.9 15.6 24.6 5.4 6.2 13.6 175.4 98.0 7.4 7.0 12.1 18.8 0.3 6.0 9.3 8.3 8.0 7.0 7.1 7.2 6.4 8.9 5.2 6.6 4.8 10.0 8.7 14.2 4.6 7.9 6.0 5.9 5.5 4.6 6.0 5.4 7.8 5.9 6.4 6.6 5.8 8.4 5.8 0.8 3.2 4.1 0.0 2.2 0.4 0.4 0.9 1.8 4.3 1.4 0.9 1.1 8.6 3.7 1.8 0.0 1.0 2.2 19.7 5.9 0.8 8.9 2.3 1.2 3.0 4.2 2.1 0.0 3.8 1.0 2.9 4.1 1.5 0.0 1.2 1.1 21.6 1.1 5.0 0.0 5.1 4.1 0.9 0.2 21.6 0.6 1.2 0.0 0.0 1.5 9.3 3.1 0.0 0.0 2.6 4.5 2.2 1.6 0.6 4.7 38.5 3.1 0.9 0.0 1.7 3.7 0.7 0.7 3.4 0.6 0.3 1.5 1.2 4.4 0.4 AMPH ENSG00000078053 Amphiphysin P49418 7 38383704-38631420 "Cancer-related genes, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 48.9;pituitary gland: 21.3;retina: 65.9" "Group enriched" "Detected in many" 5 "Bipolar cells: 72.2;Cone photoreceptor cells: 87.6;Excitatory neurons: 228.2;Inhibitory neurons: 198.4;Oligodendrocyte precursor cells: 96.5;Rod photoreceptor cells: 59.4" "Cancer enhanced" "Detected in many" "glioma: 3.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 64.6;ASC TERT1: 37.8;BJ hTERT+ SV40 Large T+: 25.4;BJ hTERT+ SV40 Large T+ RasG12V: 29.9;GAMG: 44.8;HBF TERT88: 23.1;U-138 MG: 24.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008559, HPA019828, HPA019829" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "CAB008559: AB_1611845, HPA019828: AB_1844801, HPA019829: AB_1844802" "unprognostic (1.76e-2)" "unprognostic (1.59e-1)" "unprognostic (5.94e-2)" "unprognostic (7.36e-2)" "unprognostic (3.24e-3)" "unprognostic (2.92e-1)" "unprognostic (4.90e-2)" "unprognostic (2.55e-2)" "unprognostic (4.37e-1)" "unprognostic (1.08e-1)" "prognostic favorable (9.96e-4)" "unprognostic (5.06e-2)" "unprognostic (5.81e-5)" "unprognostic (1.23e-2)" "unprognostic (5.63e-2)" "unprognostic (8.03e-2)" "unprognostic (1.68e-3)" 6.5 1.3 19.2 1.5 21.9 0.0 5.9 7.2 48.9 5.8 0.0 3.7 0.5 4.0 3.4 3.2 4.7 3.0 5.4 27.3 28.8 2.6 0.4 1.0 0.4 11.2 0.8 0.9 1.8 0.3 21.3 0.0 10.9 1.4 1.4 65.9 2.5 2.9 3.6 1.3 1.8 3.8 7.9 1.9 2.8 2.5 5.4 0.7 1.7 9.6 0.2 2.4 2.9 17.5 0.0 0.0 16.7 0.0 64.6 37.8 0.0 2.4 0.0 25.4 29.9 0.0 0.0 0.0 0.0 4.8 44.8 0.0 0.0 0.0 23.1 0.0 2.0 0.2 0.0 0.0 0.0 0.3 0.1 22.4 0.0 0.0 0.0 0.1 2.0 0.6 0.0 0.5 0.1 0.3 0.0 0.3 8.5 0.0 0.0 0.0 0.0 1.9 0.0 0.1 4.9 0.0 0.0 0.0 0.7 0.5 0.1 0.0 0.0 24.6 17.1 8.8 9.8 0.1 0.3 0.0 16.8 0.3 22.6 0.0 0.2 0.0 0.6 0.0 0.4 0.0 0.2 0.3 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.4 0.0 0.0 19.2 21.9 7.2 48.9 27.3 28.8 11.2 0.8 10.9 7.9 5.4 17.5 0.8 0.0 0.0 22.5 0.6 0.3 0.1 0.0 0.0 72.2 3.1 2.2 7.9 0.0 0.0 0.0 87.6 0.0 0.3 0.0 1.9 0.3 9.9 0.4 3.2 1.1 0.0 0.0 228.2 0.0 0.0 8.6 0.0 0.3 0.0 0.2 3.9 0.1 0.1 1.7 198.4 0.0 0.0 13.0 1.1 15.0 2.8 0.7 0.0 22.5 0.5 7.6 3.1 96.5 5.5 0.1 0.0 4.9 0.1 0.0 0.0 0.0 0.0 59.4 6.6 8.3 8.4 4.7 2.8 0.0 0.3 0.0 0.6 2.0 0.0 0.0 ANKFN1 FLJ38335 ENSG00000153930 "Ankyrin repeat and fibronectin type III domain containing 1" Q8N957 17 55882301-56511659 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 11.3;cervix: 9.2;fallopian tube: 5.3" "Cell type enhanced" "Detected in some" "Astrocytes: 138.4;Excitatory neurons: 27.2;Inhibitory neurons: 86.6;Oligodendrocyte precursor cells: 70.9;Respiratory ciliated cells: 31.0" "Cancer enhanced" "Detected in some" "glioma: 0.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HeLa: 6.8;MOLT-4: 15.4;T-47d: 5.0;U-2197: 4.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021566, HPA022538, HPA048953" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane" "HPA021566: AB_1844828, HPA022538: AB_1844829, HPA048953: " "unprognostic (6.64e-2)" "unprognostic (1.29e-1)" "unprognostic (3.52e-2)" "unprognostic (9.38e-5)" "unprognostic (2.39e-1)" "unprognostic (2.31e-3)" "unprognostic (3.84e-2)" "unprognostic (1.68e-1)" "unprognostic (3.31e-1)" "unprognostic (1.21e-1)" "unprognostic (1.24e-2)" "unprognostic (6.81e-3)" "unprognostic (3.44e-8)" "unprognostic (1.24e-1)" "unprognostic (1.69e-1)" "unprognostic (4.93e-2)" "unprognostic (9.51e-2)" 0.7 0.2 5.3 0.0 3.6 0.0 0.3 3.6 1.8 9.2 0.6 0.1 0.1 0.1 0.9 0.2 5.3 0.2 0.0 3.1 8.4 0.1 0.0 0.7 0.0 7.5 11.3 0.0 0.0 0.0 0.3 0.8 6.2 0.2 0.1 0.2 0.2 0.1 0.0 2.2 0.1 0.0 7.7 0.0 0.3 1.7 9.7 0.6 0.1 0.0 0.0 1.0 0.9 3.0 0.0 0.0 0.1 0.0 1.1 0.1 0.3 0.0 2.5 0.1 0.2 0.0 0.0 0.2 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 6.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.9 0.1 0.4 15.4 0.0 0.0 0.8 0.6 0.1 0.0 0.0 0.0 0.0 1.0 0.0 1.5 0.0 0.2 0.0 5.0 0.0 0.0 0.0 0.3 4.8 0.0 1.3 0.2 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 3.6 3.6 1.8 3.1 8.4 7.5 11.3 6.2 7.7 9.7 3.0 0.0 0.0 1.1 138.4 0.0 0.5 0.1 0.6 0.0 0.0 0.3 0.1 0.6 0.0 0.6 0.0 0.0 0.7 0.0 0.0 0.0 0.0 18.7 16.9 1.2 0.3 0.0 0.0 27.2 0.0 0.9 1.1 0.0 0.9 0.0 0.2 0.0 0.0 0.0 0.0 86.6 2.4 0.0 0.0 0.7 8.6 0.6 0.0 1.8 11.2 0.0 0.3 0.0 70.9 3.0 0.0 0.1 0.0 0.0 0.3 0.2 0.1 31.0 0.1 6.6 0.0 0.5 6.4 2.7 0.0 0.4 2.9 0.0 0.0 0.1 1.4 ANKIB1 "DKFZP434A0225, KIAA1386" ENSG00000001629 "Ankyrin repeat and IBR domain containing 1" Q9P2G1 7 92245974-92401383 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 85.5" "Cell type enhanced" "Detected in all" "Excitatory neurons: 182.5;Inhibitory neurons: 218.0;Oligodendrocyte precursor cells: 176.5;Oligodendrocytes: 590.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019358, HPA021780" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA019358: AB_1844831, HPA021780: AB_2670819" "unprognostic (1.77e-1)" "unprognostic (5.96e-3)" "unprognostic (1.23e-1)" "unprognostic (4.97e-3)" "unprognostic (2.75e-1)" "unprognostic (7.67e-2)" "unprognostic (4.88e-3)" "unprognostic (2.14e-1)" "unprognostic (4.24e-2)" "unprognostic (1.87e-2)" "unprognostic (1.52e-3)" "unprognostic (1.48e-1)" "unprognostic (1.06e-3)" "unprognostic (4.05e-2)" "unprognostic (3.00e-1)" "unprognostic (3.00e-2)" "unprognostic (3.20e-1)" 12.6 10.6 28.4 10.0 56.8 6.9 12.3 21.2 42.0 12.6 0.0 12.9 11.1 12.0 15.9 11.8 9.8 14.9 10.2 19.0 54.6 25.6 10.6 11.0 13.2 32.9 32.4 12.6 12.2 23.9 7.5 12.7 34.5 10.0 12.8 9.9 13.9 11.2 7.7 14.4 12.0 13.6 14.0 12.4 11.7 20.8 36.3 14.5 17.2 9.9 11.7 13.2 9.0 85.5 35.7 20.9 18.7 27.3 32.0 34.9 19.2 27.1 30.0 25.4 34.0 15.8 52.0 20.0 23.4 39.7 66.8 16.5 16.5 28.1 38.0 35.1 14.0 13.1 23.7 12.1 22.0 18.8 26.5 23.1 22.8 31.0 38.2 34.6 28.7 17.4 16.9 41.8 30.0 27.5 39.6 17.0 19.6 23.9 23.7 14.6 22.8 21.9 26.6 30.7 25.5 29.4 39.2 41.8 22.4 34.8 17.5 10.2 26.2 48.5 40.2 55.3 27.8 26.7 52.3 25.4 27.7 21.9 56.2 1.4 0.4 1.2 0.9 0.7 0.7 1.7 0.9 1.3 0.4 2.0 0.7 1.0 0.2 1.2 0.6 1.6 1.9 0.4 28.4 56.8 21.2 42.0 19.0 54.6 32.9 32.4 34.5 14.0 36.3 85.5 24.1 25.6 30.4 97.6 21.8 18.6 17.5 16.4 13.1 20.8 25.6 20.2 33.4 24.3 22.3 27.6 18.8 13.4 27.8 20.7 1.9 21.5 52.8 21.5 37.2 22.4 41.9 8.8 182.5 19.2 25.2 25.9 14.3 27.0 26.6 47.4 27.8 15.1 13.5 30.3 218.0 24.8 10.2 22.2 16.1 61.1 33.2 20.4 17.8 87.1 20.6 27.3 34.0 176.5 590.8 33.5 11.8 40.6 23.4 26.5 20.8 37.3 18.8 16.2 19.7 34.8 26.1 70.9 50.4 20.3 22.7 14.0 22.7 31.2 21.7 21.9 ANKLE2 "KIAA0692, Lem4, LEMD7" ENSG00000176915 "Ankyrin repeat and LEM domain containing 2" Q86XL3 12 132725503-132761832 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell cycle, Cell division, Mitosis" "Disease variant, Primary microcephaly" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 215.7;Urothelial cells: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003602, HPA074838" Uncertain Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 71: Testis - DNA repair" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003602: AB_1858349, HPA074838: " "unprognostic (4.43e-2)" "unprognostic (6.92e-2)" "unprognostic (7.97e-2)" "unprognostic (9.84e-3)" "unprognostic (1.97e-2)" "unprognostic (5.81e-2)" "prognostic unfavorable (3.97e-6)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (4.76e-2)" "unprognostic (6.10e-2)" "prognostic unfavorable (1.90e-8)" "unprognostic (1.42e-1)" "unprognostic (1.42e-1)" "unprognostic (6.92e-3)" "unprognostic (2.09e-1)" 30.0 37.6 12.4 27.0 13.3 38.4 27.8 15.2 16.6 25.4 21.9 23.8 17.8 24.9 19.0 33.6 25.2 17.4 22.0 13.8 14.1 21.8 22.9 31.3 31.6 12.3 12.4 27.1 24.6 17.9 23.1 20.4 12.3 23.9 16.1 12.3 26.1 15.6 29.3 36.9 33.3 21.9 12.0 37.9 24.1 55.7 14.3 26.2 23.3 18.3 31.2 25.0 27.6 13.2 50.7 46.4 47.3 29.5 26.9 42.1 59.1 60.2 44.7 59.0 45.0 53.2 33.6 39.5 30.7 53.1 39.5 59.2 41.8 54.8 56.2 17.0 51.6 50.1 84.0 25.2 29.9 54.6 34.0 39.1 54.9 56.2 41.3 108.8 42.8 32.0 46.1 15.1 61.2 36.4 51.1 89.4 40.1 24.8 43.9 58.0 31.1 16.7 42.6 64.9 57.9 35.6 77.7 32.4 27.1 44.1 56.9 39.1 61.5 70.5 50.9 38.0 68.1 27.9 29.5 47.9 54.7 35.8 40.5 0.9 1.2 4.4 1.8 1.1 2.4 2.7 2.6 2.8 1.7 2.8 2.4 2.0 0.7 2.7 1.3 1.7 2.6 0.7 12.4 13.3 15.2 16.6 13.8 14.1 12.3 12.4 12.3 12.0 14.3 13.2 38.0 73.7 31.2 18.3 43.2 67.3 92.0 38.2 32.5 32.3 31.2 27.1 24.6 27.1 51.3 31.3 45.9 29.2 41.1 33.8 1.9 33.2 109.1 58.6 52.4 36.3 20.8 23.1 21.0 32.7 35.5 35.7 35.2 119.2 18.4 38.3 22.9 12.9 20.1 32.0 17.8 18.0 24.4 19.7 47.6 24.5 25.1 35.5 33.8 16.9 40.6 21.9 47.4 18.1 18.4 101.9 24.8 28.2 47.6 116.9 18.8 8.5 32.3 39.7 26.3 39.2 40.5 215.7 61.8 44.8 72.9 36.5 44.7 31.6 24.0 168.7 ANKRD35 FLJ25124 ENSG00000198483 "Ankyrin repeat domain 35" Q8N283 1 145866560-145885866 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 60.8" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 56.4;Fibroblasts: 31.2;Leydig cells: 36.4;Muller glia cells: 57.7;Peritubular cells: 50.8;Skeletal myocytes: 29.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "classical monocyte: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "ASC TERT1: 9.6;THP-1: 6.8;TIME: 8.4;U-87 MG: 8.3;U-937: 7.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035453 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA035453: AB_10672864" "prognostic favorable (9.35e-4)" "prognostic favorable (2.90e-4)" "unprognostic (2.07e-1)" "unprognostic (7.39e-3)" "unprognostic (1.77e-2)" "unprognostic (1.02e-2)" "unprognostic (3.27e-1)" "unprognostic (3.58e-2)" "unprognostic (3.03e-1)" "unprognostic (1.79e-1)" "unprognostic (2.98e-1)" "unprognostic (5.86e-2)" "unprognostic (9.29e-10)" "unprognostic (8.80e-3)" "unprognostic (2.18e-1)" "unprognostic (5.92e-2)" "unprognostic (8.69e-3)" 4.0 1.3 8.2 1.1 7.9 0.3 4.6 7.6 9.7 20.6 6.4 6.0 0.5 5.8 1.4 24.7 6.6 1.3 2.9 7.5 8.6 0.8 2.5 2.3 0.4 8.7 9.5 4.4 0.7 0.0 2.0 0.1 8.5 6.6 0.8 1.3 11.4 2.7 8.2 60.8 2.5 2.1 8.4 0.5 3.9 1.6 9.0 0.5 1.7 3.8 6.7 7.3 20.6 7.6 0.1 0.0 0.0 0.0 2.2 9.6 0.2 1.4 3.6 0.4 1.2 0.4 0.0 0.0 0.3 1.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.0 1.1 2.9 0.1 3.3 0.4 0.3 0.0 0.1 0.4 0.0 0.0 0.0 2.2 0.0 0.0 3.9 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 8.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 8.3 7.5 0.0 0.0 2.1 0.0 0.7 0.8 0.1 0.0 0.3 1.1 0.3 0.0 0.2 0.7 0.1 0.7 0.2 0.5 0.7 0.7 8.2 7.9 7.6 9.7 7.5 8.6 8.7 9.5 8.5 8.4 9.0 7.6 1.6 0.0 0.0 6.8 0.3 4.6 16.8 10.2 0.0 1.1 6.3 13.5 1.5 2.8 9.5 1.8 0.0 0.1 2.2 0.0 0.0 0.0 3.5 56.4 10.9 1.3 0.0 2.7 5.6 0.4 0.1 31.2 0.5 17.2 19.1 0.0 2.2 13.9 11.0 0.0 2.1 0.0 14.2 1.2 4.6 5.9 36.4 1.1 5.4 1.0 1.1 57.7 5.2 3.0 0.6 0.1 0.0 50.8 0.4 5.3 0.0 0.1 9.8 2.7 0.0 29.5 6.4 0.1 1.0 10.4 12.4 0.3 5.5 1.1 0.0 13.6 ANO1 "DOG1, FLJ10261, ORAOV2, TAOS2, TMEM16A" ENSG00000131620 "Anoctamin 1" Q5XXA6 11 70078302-70189528 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Developmental protein, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "epididymis: 181.7;salivary gland: 180.5;seminal vesicle: 209.2" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 70.2;Early spermatids: 54.9;Hepatocytes: 141.3;Late spermatids: 75.1;Sertoli cells: 46.0;Smooth muscle cells: 52.5;Suprabasal keratinocytes: 46.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "A-431: 140.2;CAPAN-2: 207.9;HaCaT: 254.0;OE19: 182.2" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "spinal cord: 6.6" "HPA032148, HPA057356" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Nucleoplasm "HPA032148: AB_2674180, HPA057356: AB_2732610" "unprognostic (2.73e-1)" "unprognostic (7.91e-2)" "unprognostic (3.66e-2)" "prognostic favorable (4.58e-6)" "unprognostic (1.90e-1)" "prognostic unfavorable (7.28e-5)" "unprognostic (1.16e-3)" "prognostic unfavorable (2.40e-4)" "unprognostic (2.13e-2)" "unprognostic (3.51e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.21e-1)" "prognostic unfavorable (4.09e-6)" "unprognostic (1.56e-1)" "unprognostic (1.06e-1)" "unprognostic (8.85e-3)" "unprognostic (1.81e-1)" 16.3 2.2 0.3 3.6 1.6 0.1 86.8 0.8 1.3 46.7 0.1 14.3 3.6 40.0 181.7 12.7 59.1 54.4 21.9 0.5 0.1 6.4 108.5 16.1 3.4 1.0 0.2 2.9 9.1 48.0 4.4 5.2 1.1 17.1 11.0 0.9 180.5 209.2 12.7 97.4 4.6 30.1 0.2 1.2 48.3 10.4 0.1 1.5 35.4 33.0 4.0 6.7 12.8 0.5 140.2 5.3 0.3 4.5 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 207.9 0.0 2.5 0.0 0.3 254.0 0.0 0.7 0.0 0.4 0.2 0.1 0.1 0.0 0.0 0.3 0.2 0.0 0.1 0.4 0.2 0.0 0.6 0.0 0.0 0.1 0.0 1.0 0.5 0.3 1.1 182.2 19.6 0.3 0.0 0.7 0.0 0.2 7.3 0.2 0.1 43.1 0.8 1.4 16.2 0.5 0.5 0.3 1.1 0.0 3.5 0.1 0.3 0.2 0.2 0.0 14.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.6 0.8 1.3 0.5 0.1 1.0 0.2 1.1 0.2 0.1 0.5 7.2 0.0 0.0 0.7 0.4 17.7 21.5 4.2 0.0 0.0 30.5 70.2 3.5 17.2 2.0 0.0 0.0 1.3 0.2 0.4 0.0 4.1 54.9 10.0 27.5 5.6 0.0 2.7 0.7 0.0 0.6 4.2 36.7 18.5 4.5 0.0 3.3 141.3 0.2 0.0 20.4 13.3 0.0 1.6 3.0 75.1 1.8 0.7 5.4 2.8 0.0 0.8 0.0 1.5 0.7 1.0 0.5 1.5 0.3 22.6 0.0 0.7 0.3 0.4 46.0 1.1 52.5 1.4 2.3 1.4 46.7 4.1 0.7 0.1 0.4 20.9 ANO10 "FLJ10375, MGC47890, SCAR10, TMEM16K" ENSG00000160746 "Anoctamin 10" Q9NW15 3 43354859-43691594 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 123.3;Excitatory neurons: 77.4;Inhibitory neurons: 97.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA016624, HPA051569" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 37: Intestine - Unknown function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA016624: , HPA051569: AB_2681537" "unprognostic (1.51e-3)" "unprognostic (1.38e-2)" "prognostic favorable (6.70e-4)" "prognostic favorable (1.11e-4)" "unprognostic (4.23e-1)" "unprognostic (2.69e-2)" "prognostic unfavorable (3.19e-4)" "unprognostic (7.99e-3)" "unprognostic (1.03e-2)" "unprognostic (1.56e-1)" "unprognostic (1.05e-1)" "unprognostic (1.33e-1)" "prognostic favorable (6.41e-6)" "unprognostic (9.83e-3)" "unprognostic (1.22e-1)" "unprognostic (5.19e-3)" "unprognostic (5.71e-2)" 26.6 14.1 17.6 15.1 18.6 33.0 21.8 23.9 20.9 22.3 18.4 39.4 61.1 21.6 13.6 25.3 13.9 19.4 12.7 18.1 21.1 29.9 14.1 16.9 7.6 22.7 22.9 13.9 15.2 23.7 13.9 18.1 23.2 14.2 33.7 10.1 28.6 20.2 15.5 32.0 54.7 28.0 19.6 9.1 13.5 13.0 19.8 7.1 24.5 11.6 9.7 18.1 21.5 24.1 30.6 23.6 26.1 27.4 101.1 53.5 31.2 87.7 141.1 42.0 54.4 16.2 27.5 3.1 27.4 114.8 43.1 16.3 20.6 47.0 52.6 33.6 14.2 39.4 28.7 17.7 43.9 7.2 31.1 50.5 36.3 53.6 71.8 79.4 100.3 18.7 30.8 24.9 95.2 20.8 7.8 5.2 31.3 23.7 28.6 6.3 18.7 10.2 85.5 31.4 6.4 19.4 34.4 27.0 19.8 45.3 59.5 14.5 84.7 66.2 24.4 70.2 40.7 15.7 22.9 1.1 60.2 14.6 44.2 7.4 19.0 1.4 6.7 11.1 3.8 2.7 4.6 4.5 13.1 2.5 3.9 6.0 32.8 9.7 12.7 2.3 5.4 7.0 17.6 18.6 23.9 20.9 18.1 21.1 22.7 22.9 23.2 19.6 19.8 24.1 24.3 6.4 3.2 70.2 4.1 5.6 5.8 6.9 8.0 8.0 18.2 8.4 5.2 8.6 13.2 14.7 0.0 14.4 3.7 38.5 123.3 21.6 2.9 11.8 23.6 17.8 9.6 11.8 77.4 17.8 19.5 10.6 10.2 31.2 2.5 6.8 23.6 10.7 11.6 10.1 97.9 23.8 10.2 9.6 5.3 5.2 5.6 9.1 14.2 69.3 9.2 17.1 5.2 71.4 46.4 11.7 22.1 10.1 2.6 4.4 58.4 19.0 4.0 3.6 6.6 19.1 15.7 17.1 23.6 8.7 6.1 17.1 5.8 6.2 26.9 4.8 ANO2 "C12orf3, TMEM16B" ENSG00000047617 "Anoctamin 2" Q9NQ90 12 5531869-5946232 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "retina: 226.0" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 81.3;Early spermatids: 57.3;Late spermatids: 283.2;Microglial cells: 143.4;Rod photoreceptor cells: 179.9" "Cancer enhanced" "Detected in some" "testis cancer: 2.4" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "basophil: 1.8" "Lineage enriched" "Detected in single" 19 "granulocytes: 1.8" "Cell line enhanced" "Detected in some" "BJ hTERT+: 9.6;HUVEC TERT2: 9.5;U-2 OS: 24.1" "Region enriched" "Detected in many" 4 "basal ganglia: 19.6" "HPA036276, HPA057499" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 9: U-2 OS - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA036276: AB_10670713, HPA057499: AB_2732613" "unprognostic (6.32e-2)" "unprognostic (1.01e-1)" "unprognostic (3.77e-1)" "unprognostic (1.25e-2)" "unprognostic (1.55e-1)" "unprognostic (4.05e-3)" "unprognostic (2.86e-1)" "unprognostic (2.62e-1)" "unprognostic (1.11e-2)" "unprognostic (1.90e-1)" "unprognostic (1.84e-3)" "unprognostic (3.78e-3)" "unprognostic (1.04e-2)" "unprognostic (1.10e-2)" "unprognostic (9.93e-2)" "unprognostic (2.27e-1)" "unprognostic (2.17e-1)" 8.8 0.3 3.8 0.4 4.4 0.0 6.6 2.2 3.3 4.3 5.0 1.9 0.7 1.8 1.4 1.7 3.2 1.1 8.0 2.5 2.4 1.2 0.2 7.2 0.1 3.2 3.2 1.5 0.9 1.3 0.6 4.1 3.4 2.5 0.6 226.0 1.3 1.0 2.0 1.1 1.7 1.5 3.0 3.4 2.2 10.1 3.9 0.3 2.4 4.4 0.2 2.4 3.5 2.8 2.5 0.0 4.4 0.0 0.0 0.2 2.0 0.0 9.6 0.5 1.0 0.0 0.2 0.2 0.3 0.0 0.1 0.3 0.0 0.1 0.7 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.5 0.0 0.0 1.9 0.0 1.0 0.0 0.0 4.6 2.3 0.0 1.9 0.0 1.0 0.1 0.1 0.0 0.0 2.3 1.6 0.0 3.9 1.3 0.0 0.2 0.0 24.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 3.8 4.4 2.2 3.3 2.5 2.4 3.2 3.2 3.4 3.0 3.9 2.8 9.7 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.6 11.5 0.3 0.1 1.9 0.0 0.0 0.0 81.3 1.4 0.0 0.0 0.0 0.0 57.3 0.4 0.4 9.1 0.0 0.0 1.7 0.0 2.0 0.3 0.0 0.5 0.0 0.0 4.6 0.0 0.2 10.1 2.0 0.0 0.0 0.0 0.0 283.2 0.3 0.1 0.0 143.4 0.0 13.0 0.0 31.2 9.9 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 179.9 0.0 1.3 0.6 1.4 1.8 0.0 0.1 2.5 0.0 0.2 0.2 0.0 ANO6 "DKFZp313M0720, TMEM16F" ENSG00000177119 "Anoctamin 6" Q4KMQ2 12 45215987-45482280 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Ion transport, Lipid transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038958 Approved Approved "Plasma membrane,Cytosol" NA NA 47000 "Cluster 14: Monocytes - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 32: U-937 - Innate immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA038958: AB_10672835" "prognostic unfavorable (7.56e-5)" "prognostic unfavorable (3.82e-4)" "unprognostic (2.16e-1)" "unprognostic (1.75e-2)" "unprognostic (1.29e-1)" "unprognostic (9.82e-3)" "unprognostic (7.43e-2)" "unprognostic (3.01e-3)" "unprognostic (7.55e-2)" "unprognostic (2.84e-3)" "unprognostic (1.41e-3)" "unprognostic (3.02e-1)" "unprognostic (2.68e-2)" "unprognostic (1.26e-3)" "unprognostic (1.26e-1)" "unprognostic (4.20e-2)" "unprognostic (1.28e-1)" 86.4 25.9 7.4 16.8 8.0 9.8 27.5 7.9 8.4 28.9 13.8 29.9 36.2 38.9 25.6 25.0 27.2 31.6 27.7 7.2 10.5 36.2 56.9 40.2 13.4 10.4 8.5 56.6 25.3 58.8 6.9 50.5 10.1 29.9 15.0 3.6 25.4 37.1 56.0 12.0 51.4 48.4 9.0 16.0 13.8 11.8 9.1 24.9 13.2 46.3 12.8 35.0 16.0 9.3 41.5 44.3 25.7 35.4 119.1 61.7 97.4 57.4 72.5 38.4 36.3 71.9 61.5 21.1 52.2 92.0 34.9 54.0 24.1 32.3 45.6 31.4 16.9 25.0 17.8 62.1 37.8 39.5 19.4 51.7 31.9 33.0 48.7 95.4 52.6 44.5 19.3 34.0 42.7 11.2 41.5 13.2 28.6 0.0 18.0 23.4 33.3 24.4 36.9 63.1 11.7 39.9 59.9 36.8 27.9 67.7 43.3 62.8 70.6 41.2 26.1 41.8 29.3 18.3 21.5 25.8 37.3 122.8 33.4 3.1 5.9 1.4 2.4 6.9 2.5 1.4 2.2 2.0 5.5 1.2 2.0 1.3 0.6 2.3 7.1 2.7 3.0 4.2 7.4 8.0 7.9 8.4 7.2 10.5 10.4 8.5 10.1 9.0 9.1 9.3 65.1 60.9 11.8 54.9 10.0 30.5 20.3 27.7 23.3 1.1 23.0 18.7 23.4 30.0 21.5 18.4 0.0 34.0 14.5 2.5 3.9 38.4 1.3 13.3 32.1 37.5 8.4 8.0 49.8 37.4 28.0 44.2 21.4 26.0 12.7 20.2 52.5 88.3 19.9 0.0 49.0 11.5 12.2 56.3 22.9 3.5 51.3 46.0 17.8 68.4 29.1 8.2 15.5 110.6 3.0 73.3 10.0 40.6 12.2 29.5 70.3 23.4 16.5 0.3 39.5 45.9 52.1 3.5 4.3 25.1 22.0 24.6 17.3 6.7 14.6 30.5 ANXA13 ANX13 ENSG00000104537 "Annexin A13" P27216 8 123680794-123737402 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "gallbladder: 144.3;intestine: 293.6" "Cell type enhanced" "Detected in some" "Cholangiocytes: 180.1;Enteroendocrine cells: 44.9;Intestinal goblet cells: 161.1;Paneth cells: 58.1;Proximal enterocytes: 125.2;Undifferentiated cells: 38.5" "Group enriched" "Detected in many" 13 "colorectal cancer: 7.8;liver cancer: 8.5;pancreatic cancer: 6.1;renal cancer: 7.0;stomach cancer: 7.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A549: 27.8;HDLM-2: 14.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA018535, HPA019569, HPA019650, CAB025135" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 56: Intestine - Transmembrane transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "CAB025135: , HPA018535: AB_1844854, HPA019569: AB_1844855, HPA019650: AB_1844856" "unprognostic (6.47e-3)" "unprognostic (1.95e-1)" "unprognostic (3.50e-2)" "unprognostic (1.83e-1)" "unprognostic (5.66e-2)" "unprognostic (4.05e-2)" "unprognostic (5.48e-2)" "unprognostic (2.86e-3)" "unprognostic (2.06e-1)" "unprognostic (9.11e-2)" "unprognostic (2.48e-2)" "unprognostic (2.01e-1)" "unprognostic (1.57e-2)" "unprognostic (1.49e-1)" "unprognostic (1.03e-1)" "unprognostic (5.79e-2)" "unprognostic (4.79e-2)" 0.2 0.0 1.1 1.6 2.6 0.0 0.4 2.6 2.2 0.4 1.1 21.6 293.6 1.5 2.2 0.2 58.4 144.3 0.1 1.1 1.5 7.0 20.2 0.2 0.2 4.1 2.9 0.4 0.4 0.0 0.0 0.0 3.3 0.5 36.1 4.3 0.1 24.3 0.0 0.1 219.5 2.9 3.3 0.0 0.8 4.2 2.1 0.1 0.0 0.0 0.0 0.5 0.1 5.3 0.0 27.8 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 14.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 3.0 0.0 0.0 0.0 1.7 1.6 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 2.6 2.6 2.2 1.1 1.5 4.1 2.9 3.3 3.3 2.1 5.3 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.1 0.0 0.2 0.1 1.1 0.4 180.1 0.0 0.0 0.0 0.0 0.0 6.2 3.9 1.4 1.1 4.5 3.6 0.2 44.9 2.7 0.9 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.1 0.2 0.0 1.0 161.1 0.0 0.0 0.0 1.4 1.2 0.3 0.0 0.0 0.0 0.3 0.0 0.5 1.2 0.1 58.1 0.0 0.0 0.0 125.2 27.6 2.9 10.9 0.0 0.2 0.1 0.0 0.1 0.0 0.6 0.0 0.4 0.1 38.5 0.1 ANXA2 "ANX2, ANX2L4, CAL1H, LIP2, LPC2D" ENSG00000182718 "Annexin A2" P07355 15 60347134-60402883 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Host-virus interaction" RNA-binding "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 2185.3" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 5755.6;Pancreatic endocrine cells: 5217.8;Prostatic glandular cells: 4575.5;Urothelial cells: 4326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basophil: 4429.7;classical monocyte: 2762.3;intermediate monocyte: 2401.9;myeloid DC: 4018.8;non-classical monocyte: 2686.5;T-reg: 1681.4" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 174.7" "CAB004311, HPA046964, HPA061798" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 19000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" Cytosol "CAB004311: AB_626677, HPA046964: AB_2732537, HPA061798: AB_2732671" "unprognostic (1.61e-1)" "unprognostic (1.31e-3)" "unprognostic (1.84e-1)" "prognostic favorable (6.88e-5)" "unprognostic (4.06e-3)" "unprognostic (5.42e-3)" "prognostic unfavorable (2.54e-5)" "prognostic unfavorable (7.51e-4)" "unprognostic (2.94e-1)" "unprognostic (4.10e-3)" "prognostic unfavorable (8.47e-6)" "unprognostic (5.16e-2)" "prognostic unfavorable (2.11e-6)" "unprognostic (7.74e-2)" "unprognostic (2.55e-1)" "unprognostic (7.41e-2)" "prognostic unfavorable (6.59e-5)" 975.6 370.5 49.0 461.9 50.5 151.7 708.5 49.6 96.9 806.3 95.6 631.2 502.0 296.2 267.2 2185.3 388.4 453.9 393.0 47.6 79.4 358.3 185.5 878.3 200.7 90.0 83.6 187.0 324.3 344.0 163.9 650.4 84.9 399.3 606.1 30.2 933.4 386.4 304.8 1140.8 487.5 425.4 73.3 301.6 379.0 116.1 120.9 188.7 351.2 205.8 541.1 842.2 1256.7 80.1 4183.3 4421.4 223.6 105.5 2962.4 4744.2 971.0 4703.6 2968.4 2868.4 2534.9 2083.5 1903.6 10.0 3907.2 5983.6 2185.1 4304.9 992.9 8695.5 3113.5 846.8 103.9 78.2 1918.7 882.7 1782.0 4.5 59.9 2324.4 2278.6 2013.2 4335.0 3477.2 5455.0 58.4 320.9 447.9 6271.8 468.4 18.5 239.1 508.2 3444.1 3283.5 48.9 1198.8 226.6 5172.4 2410.7 295.1 171.9 1774.5 424.8 1942.8 2305.1 922.7 173.6 6336.8 2534.1 3406.8 8668.0 4807.4 172.6 616.3 83.8 2449.2 47.9 5206.0 4429.7 2762.3 355.0 603.8 2401.9 668.5 657.9 686.4 701.7 4018.8 412.1 77.0 313.9 73.6 287.1 2686.5 609.4 1681.4 3754.4 49.0 50.5 49.6 96.9 47.6 79.4 90.0 83.6 84.9 73.3 120.9 80.1 673.9 2141.0 414.8 0.3 101.3 2512.2 3396.9 5755.6 246.4 2.5 395.9 337.4 28.2 773.5 3086.6 560.9 0.0 1874.5 135.9 933.6 13.7 3941.4 93.0 855.9 457.1 772.0 103.4 38.7 0.2 2411.4 2714.4 1076.7 328.7 1376.3 105.7 97.5 474.0 64.2 1537.2 0.0 1.3 689.0 1668.2 429.6 1992.1 126.6 771.1 715.1 1417.6 15.9 1284.0 19.4 138.0 1.5 0.1 5217.8 920.9 638.7 144.5 4575.5 845.8 51.8 2446.8 8.1 184.1 437.7 831.1 13.0 29.3 789.7 2325.1 1150.1 224.1 8.6 749.9 4326.1 APBB1IP "INAG1, RIAM" ENSG00000077420 "Amyloid beta precursor protein binding family B member 1 interacting protein" Q7Z5R6 10 26438341-26567803 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 145.4" "Cell type enhanced" "Detected in many" "B-cells: 88.2;dendritic cells: 149.1;Kupffer cells: 117.7;Macrophages: 93.4;Microglial cells: 381.3;NK-cells: 134.9;T-cells: 125.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 182.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 101.0;MOLT-4: 87.7;REH: 195.4;U-698: 204.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA017009, HPA063903" Enhanced Enhanced "Plasma membrane,Cytosol" No NA "Cluster 1: Neutrophils - Mixed function" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA017009: AB_2669505, HPA063903: AB_2685147" "unprognostic (1.31e-2)" "unprognostic (3.26e-2)" "unprognostic (2.79e-3)" "prognostic favorable (7.48e-4)" "unprognostic (3.06e-1)" "unprognostic (1.07e-2)" "unprognostic (3.83e-2)" "unprognostic (3.05e-1)" "unprognostic (1.62e-2)" "unprognostic (3.74e-1)" "unprognostic (5.72e-2)" "unprognostic (9.75e-2)" "unprognostic (1.71e-1)" "unprognostic (7.77e-3)" "unprognostic (2.68e-2)" "unprognostic (6.00e-2)" "unprognostic (2.38e-2)" 30.7 4.7 7.0 47.8 8.0 45.5 14.5 10.4 7.6 3.5 5.7 6.1 7.1 2.2 1.6 3.4 5.9 11.6 5.7 7.6 10.4 5.0 38.3 15.5 50.0 16.4 12.5 1.5 4.3 1.6 2.8 8.8 18.0 2.6 6.7 0.6 5.1 2.1 1.4 3.4 17.8 7.5 16.0 56.6 9.2 0.8 15.5 145.4 3.5 2.7 44.3 10.5 3.6 27.3 0.1 1.8 0.0 0.0 12.8 21.2 11.3 37.0 7.2 20.8 19.8 0.0 0.0 101.0 0.5 24.9 22.2 0.1 0.0 0.0 28.6 0.0 0.0 73.3 0.2 0.0 0.0 13.9 0.1 30.3 0.0 0.7 0.0 2.6 0.0 40.5 0.1 62.0 0.0 0.0 87.7 19.5 0.1 7.9 0.0 195.4 0.1 72.4 5.8 0.0 0.1 0.0 3.4 0.3 0.1 0.3 0.1 47.6 0.1 0.0 0.5 6.8 0.1 16.8 0.0 204.7 16.9 71.0 0.0 81.5 23.8 58.5 30.2 23.6 24.9 32.6 25.8 25.9 15.4 39.5 29.3 28.8 182.9 19.1 38.9 50.3 27.2 13.4 7.0 8.0 10.4 7.6 7.6 10.4 16.4 12.5 18.0 16.0 15.5 27.3 3.2 0.0 25.3 1.6 88.2 1.1 0.1 0.1 0.6 0.1 1.6 3.2 1.0 8.6 2.6 3.7 0.0 2.2 149.1 0.1 0.0 3.9 0.4 0.7 12.8 4.7 0.0 28.2 1.1 0.0 20.7 15.0 3.6 0.4 23.4 0.1 6.8 28.9 59.9 0.0 2.9 0.2 0.0 117.7 18.4 0.3 0.0 93.4 3.6 381.3 65.2 0.0 134.9 4.0 1.5 0.1 0.1 0.0 41.7 0.1 0.0 5.1 3.7 0.2 0.0 0.9 11.3 0.1 1.1 0.4 0.1 1.4 125.9 0.4 0.1 0.1 APOLD1 "DKFZP434F0318, FLJ25138" ENSG00000178878 "Apolipoprotein L domain containing 1" Q96LR9 12 12725917-12829975 "Predicted membrane proteins" "Angiogenesis, Differentiation" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "adipose tissue: 124.5" "Cell type enriched" "Detected in many" 4 "Adipocytes: 781.6" "Cancer enhanced" "Detected in all" "renal cancer: 24.2" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "AF22: 36.7;HDLM-2: 19.3;hTERT-RPE1: 15.1" "Group enriched" "Detected in all" 4 "basal ganglia: 5.7;olfactory bulb: 20.1" "Low region specificity" "Detected in all" "HPA052462, HPA058882" Approved Approved "Nucleoplasm,Plasma membrane" No No "Cluster 6: Non-specific - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA052462: AB_2681841, HPA058882: AB_2683844" "unprognostic (1.98e-1)" "unprognostic (8.36e-3)" "unprognostic (5.28e-2)" "unprognostic (1.28e-3)" "unprognostic (1.37e-1)" "unprognostic (1.16e-2)" "unprognostic (5.58e-3)" "unprognostic (8.07e-2)" "unprognostic (3.46e-1)" "unprognostic (4.23e-2)" "unprognostic (1.35e-1)" "unprognostic (3.23e-2)" "unprognostic (4.30e-3)" "unprognostic (3.42e-3)" "unprognostic (1.81e-1)" "unprognostic (6.18e-2)" "unprognostic (1.15e-2)" 124.5 15.6 35.2 15.4 28.7 0.3 90.6 29.8 41.8 43.8 22.5 12.4 3.9 15.7 2.3 35.3 30.5 34.4 55.8 26.9 30.7 20.0 17.7 17.1 5.6 37.6 34.0 6.9 24.0 28.0 10.5 86.6 38.1 12.8 12.0 5.8 10.3 5.6 34.3 18.4 10.7 52.5 30.3 6.1 12.1 3.0 43.6 10.6 64.8 28.8 3.3 28.3 18.1 29.3 6.4 0.2 36.7 1.2 1.1 2.1 0.3 6.0 9.9 6.0 8.7 2.4 6.5 2.0 0.5 2.3 2.1 2.0 1.4 0.3 10.1 19.3 1.4 0.5 2.0 0.0 2.2 1.0 0.6 1.4 1.7 2.1 4.7 15.1 4.6 3.5 0.5 2.5 3.1 1.3 1.0 1.1 0.2 1.5 1.1 2.9 0.8 0.9 0.7 0.6 3.1 3.4 5.7 0.5 13.6 0.6 0.2 3.1 5.6 1.3 2.0 8.1 5.5 1.8 0.9 1.4 2.0 4.0 6.9 2.2 0.3 0.2 0.3 0.1 0.4 1.0 0.7 0.5 0.2 0.8 0.5 0.3 1.6 0.3 0.2 0.6 1.1 0.1 35.2 28.7 29.8 41.8 26.9 30.7 37.6 34.0 38.1 30.3 43.6 29.3 781.6 6.4 5.3 17.3 15.9 18.1 2.5 1.4 6.8 4.4 5.4 5.8 11.9 4.3 5.9 0.0 4.2 2.9 13.3 5.3 0.0 1.1 2.9 0.7 7.2 169.4 3.6 18.9 5.3 0.4 1.4 25.0 1.1 1.3 7.6 5.8 62.4 3.8 6.6 3.3 7.0 6.3 2.0 14.2 27.1 2.1 4.4 6.6 28.4 32.8 5.9 39.6 29.9 5.0 28.5 1.2 0.6 0.4 5.7 2.9 2.3 0.5 5.4 4.8 111.7 17.5 193.5 5.5 1.0 2.3 15.5 1.0 18.3 1.1 9.3 3.7 AQP10 ENSG00000143595 "Aquaporin 10" Q96PS8 1 154321090-154325325 "Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "intestine: 68.5" "Cell type enhanced" "Detected in some" "Cholangiocytes: 1.5;Erythroid cells: 1.3;granulocytes: 5.7;Hepatic stellate cells: 1.4;Macrophages: 4.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 18.0;HMC-1: 7.1;K-562: 21.0;SH-SY5Y: 4.8" "Not detected" "Not detected" "HPA062621, HPA065947" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Vesicles "HPA062621: , HPA065947: AB_2685584" "unprognostic (6.84e-2)" "unprognostic (4.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.87e-1)" "unprognostic (1.09e-1)" "unprognostic (8.45e-4)" "unprognostic (1.63e-1)" "unprognostic (3.07e-1)" "unprognostic (4.08e-2)" "unprognostic (3.99e-1)" "unprognostic (1.22e-1)" "unprognostic (1.43e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-1)" "unprognostic (7.64e-3)" 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 68.5 0.0 0.1 0.1 4.6 0.1 0.4 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 49.7 0.0 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 18.0 0.0 0.0 0.0 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 21.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.1 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.4 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.0 1.3 0.1 0.0 0.0 0.1 0.0 0.1 5.7 0.2 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.2 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.5 0.0 0.0 0.0 0.1 0.4 0.4 0.0 0.1 0.0 0.4 0.1 0.0 0.1 AQP4 MIWC ENSG00000171885 "Aquaporin 4" P55087 18 26852043-26865771 "Human disease related genes, Metabolic proteins, Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 440.5;lung: 114.8" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 1102.6;Alveolar cells type 2: 342.3;Astrocytes: 487.7;Muller glia cells: 227.2" "Cancer enriched" "Detected in some" 22 "glioma: 223.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 2.4;RPTEC TERT1: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005079, HPA014784, CAB058689" Enhanced Supported Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 12: NES - Nervous system development" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Cell Junctions" "CAB005079: AB_2274338, CAB058689: AB_2665579, HPA014784: AB_1844967" "unprognostic (7.23e-5)" "unprognostic (1.55e-1)" "unprognostic (3.19e-8)" "unprognostic (3.68e-1)" "unprognostic (1.96e-1)" "unprognostic (2.69e-2)" "unprognostic (1.74e-1)" "unprognostic (2.34e-1)" "unprognostic (5.38e-3)" "unprognostic (1.64e-3)" "unprognostic (8.98e-2)" "unprognostic (1.22e-1)" "unprognostic (4.14e-2)" "unprognostic (1.35e-1)" "unprognostic (4.10e-2)" 0.1 0.1 272.7 0.0 298.7 0.0 0.3 282.0 246.3 0.6 62.9 0.3 0.0 0.0 0.8 0.9 1.1 0.1 2.8 283.6 440.5 2.3 0.9 114.8 0.3 250.5 351.2 2.5 0.2 2.2 3.7 0.0 333.3 0.4 0.0 60.2 0.7 0.2 60.1 0.1 0.1 0.0 333.0 0.5 11.4 0.5 387.1 0.2 14.7 20.9 0.1 0.1 0.1 376.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.1 0.3 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 272.7 298.7 282.0 246.3 283.6 440.5 250.5 351.2 333.3 333.0 387.1 376.0 0.0 1102.6 342.3 487.7 0.0 0.0 0.8 0.6 0.0 3.1 0.8 0.9 13.9 4.3 76.6 3.7 6.2 0.0 0.0 0.1 3.9 0.3 0.0 0.7 0.1 1.8 0.0 0.0 3.0 0.0 0.0 0.8 0.0 0.0 3.8 0.0 0.0 0.5 0.0 1.7 1.1 0.0 0.0 0.0 0.3 0.0 5.0 0.8 0.0 9.4 0.0 227.2 0.0 12.1 1.6 0.0 0.0 0.0 0.0 0.7 0.0 0.0 23.1 9.1 0.0 4.3 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 2.0 ARF1 ENSG00000143761 "ADP ribosylation factor 1" P84077 1 228082660-228099212 "Disease related genes, Predicted intracellular proteins" "ER-Golgi transport, Protein transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB007742 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB007742: AB_562043" "unprognostic (9.54e-2)" "unprognostic (1.35e-2)" "unprognostic (2.30e-2)" "unprognostic (2.50e-3)" "unprognostic (2.33e-1)" "prognostic unfavorable (1.55e-4)" "unprognostic (4.65e-2)" "unprognostic (1.78e-1)" "unprognostic (3.73e-1)" "unprognostic (8.95e-3)" "unprognostic (6.74e-2)" "unprognostic (2.96e-2)" "unprognostic (5.85e-2)" "unprognostic (2.69e-2)" "unprognostic (1.56e-1)" "unprognostic (8.57e-2)" "unprognostic (1.94e-1)" 268.3 282.5 213.8 176.7 222.5 426.9 241.9 188.1 261.9 249.1 215.1 259.8 242.6 266.6 193.1 304.7 247.5 189.2 340.0 242.7 231.3 257.0 324.7 298.2 185.0 200.6 201.6 237.3 327.6 296.9 299.1 276.9 207.6 244.0 177.3 96.7 355.2 203.9 330.9 237.3 240.8 176.2 196.6 251.4 265.6 193.9 218.9 184.4 240.3 206.4 154.7 229.0 233.1 206.4 476.6 321.6 257.4 257.9 289.9 362.6 425.7 409.5 433.0 444.3 386.8 383.6 442.7 239.9 428.8 438.3 204.6 298.8 316.4 399.4 219.4 355.3 506.8 234.3 209.8 386.6 559.5 342.1 333.8 350.4 476.7 408.6 427.0 374.1 443.3 267.0 456.0 533.3 431.4 341.8 350.0 495.9 331.7 656.7 643.0 279.0 228.1 750.6 315.1 242.1 362.6 320.0 265.9 790.0 466.8 87.8 543.9 681.0 406.0 324.6 256.5 479.4 626.8 498.5 301.0 331.1 445.9 285.0 670.6 1003.7 556.5 625.5 387.3 527.8 472.4 276.7 328.0 359.8 423.6 261.3 253.2 280.8 863.6 345.5 528.2 571.4 417.9 1082.4 213.8 222.5 188.1 261.9 242.7 231.3 200.6 201.6 207.6 196.6 218.9 206.4 276.9 173.1 185.2 25.8 205.1 262.6 281.7 248.0 104.2 114.3 209.1 172.0 139.8 125.8 208.1 115.8 45.9 373.7 267.8 487.8 230.9 422.7 236.3 164.6 218.7 247.2 230.1 173.8 42.3 404.5 565.8 227.3 142.8 240.8 198.3 128.8 152.4 124.8 409.4 158.2 41.1 436.9 213.6 198.8 256.2 429.9 229.2 300.1 300.6 35.6 356.0 162.2 214.2 30.7 40.7 400.2 407.2 227.2 282.8 344.6 370.1 173.3 180.7 80.2 230.1 149.6 416.0 321.1 155.7 158.3 286.0 676.7 224.9 174.6 335.2 370.0 ARHGAP17 "FLJ10308, FLJ13219, NADRIN, RICH1, WBP15" ENSG00000140750 "Rho GTPase activating protein 17" Q68EM7 16 24919389-25015666 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041703, HPA075891" Approved Supported "Plasma membrane,Cytosol" NA NA 21000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA041703: AB_10794304, HPA075891: " "unprognostic (1.79e-1)" "unprognostic (8.98e-2)" "unprognostic (8.11e-2)" "prognostic favorable (3.59e-4)" "unprognostic (4.42e-2)" "unprognostic (3.49e-2)" "prognostic unfavorable (4.95e-4)" "unprognostic (3.02e-2)" "unprognostic (6.62e-2)" "unprognostic (8.81e-3)" "unprognostic (4.99e-2)" "unprognostic (3.45e-2)" "unprognostic (1.38e-2)" "unprognostic (1.94e-1)" "unprognostic (3.91e-2)" "unprognostic (1.26e-1)" "prognostic unfavorable (3.76e-4)" 46.0 40.5 8.2 15.2 9.8 9.2 37.2 9.2 10.2 29.9 9.6 32.7 11.3 28.9 7.9 33.6 28.6 11.9 48.1 7.9 9.2 25.9 22.9 31.8 24.9 10.6 9.5 24.8 24.1 9.3 30.3 15.3 10.4 23.6 12.2 2.3 21.3 7.9 41.0 34.3 39.2 11.6 8.7 66.8 28.9 25.5 9.7 12.0 28.2 11.1 20.9 25.6 29.8 11.6 28.5 16.7 21.9 23.1 22.0 23.0 23.7 18.1 19.3 20.9 20.4 25.9 11.5 13.0 12.0 36.4 19.9 7.7 21.8 12.8 22.2 20.0 26.1 10.8 37.8 43.3 25.0 15.5 10.7 29.4 7.7 22.6 16.3 15.0 35.7 11.7 14.3 0.0 23.6 20.8 14.3 19.8 25.2 8.1 13.7 68.1 17.9 5.2 25.9 6.4 14.6 14.5 18.6 20.5 8.2 17.5 11.1 40.2 46.7 15.5 11.9 35.6 15.1 13.0 17.3 7.5 19.1 22.6 14.1 5.6 9.7 9.0 6.3 17.5 5.7 25.3 5.5 6.3 14.6 22.8 6.2 6.1 4.8 6.2 15.8 25.9 8.0 8.1 8.2 9.8 9.2 10.2 7.9 9.2 10.6 9.5 10.4 8.7 9.7 11.6 33.8 9.6 11.0 26.8 46.3 14.5 6.8 8.9 14.2 6.4 11.0 9.7 24.9 7.2 9.1 5.5 10.4 11.1 36.3 49.5 3.9 13.3 6.3 30.6 21.8 32.3 21.0 16.2 28.8 16.0 18.9 16.0 15.3 66.4 7.0 16.9 26.7 6.8 27.1 10.1 33.0 21.8 8.2 30.3 21.7 10.8 13.4 25.2 16.0 59.0 22.8 6.4 14.4 40.2 68.9 17.6 27.2 11.7 11.5 11.1 35.4 5.0 8.5 7.5 26.3 15.5 43.8 7.0 11.7 24.7 24.0 15.7 21.1 15.9 19.7 12.2 ARHGAP24 "DKFZP564B1162, FilGAP, FLJ33877" ENSG00000138639 "Rho GTPase activating protein 24" Q8N264 4 85475150-86002668 "Predicted intracellular proteins" "Angiogenesis, Differentiation" "Developmental protein, GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 99.8" "Group enriched" "Detected in many" 4 "Astrocytes: 1364.3;Microglial cells: 905.0" "Cancer enhanced" "Detected in all" "renal cancer: 9.0" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 15.9;memory B-cell: 47.3;naive B-cell: 36.8;plasmacytoid DC: 12.7" "Group enriched" "Detected in many" 5 "B-cells: 47.3;dendritic cells: 12.7;monocytes: 15.9" "Cell line enhanced" "Detected in many" "ASC diff: 109.0;ASC TERT1: 65.5;HHSteC: 63.6;HUVEC TERT2: 121.9;RPTEC TERT1: 67.2;TIME: 87.0;U-138 MG: 59.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014288 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 7: Kidney - Transmembrane transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA014288: AB_1844994" "unprognostic (2.19e-1)" "unprognostic (1.30e-1)" "unprognostic (1.14e-1)" "unprognostic (2.95e-2)" "unprognostic (2.81e-1)" "unprognostic (9.22e-2)" "unprognostic (5.75e-3)" "unprognostic (4.28e-3)" "unprognostic (3.66e-1)" "unprognostic (1.33e-1)" "unprognostic (5.91e-2)" "unprognostic (6.45e-2)" "prognostic favorable (1.67e-11)" "unprognostic (1.75e-2)" "unprognostic (6.86e-2)" "unprognostic (2.50e-2)" "unprognostic (8.75e-4)" 14.6 2.2 6.5 7.5 5.1 18.7 9.2 6.2 5.8 5.5 3.9 7.4 7.3 9.4 4.6 6.1 4.1 10.9 27.3 5.7 6.6 99.8 9.5 15.7 10.5 15.7 11.5 5.5 30.1 8.1 5.4 22.4 17.2 5.4 6.1 8.4 10.6 7.2 10.2 7.0 10.3 14.1 12.1 16.4 26.0 3.4 10.4 7.5 27.8 7.7 15.5 9.1 5.6 19.1 3.0 6.2 4.4 0.1 109.0 65.5 4.8 21.5 28.5 5.2 8.4 0.1 0.0 2.8 7.4 48.8 6.4 0.0 0.2 9.0 11.0 0.0 1.2 3.6 0.6 0.2 63.6 0.4 0.0 48.4 0.9 10.3 4.7 23.9 121.9 0.0 6.6 0.4 46.1 0.0 0.1 0.0 0.3 1.5 11.3 0.6 22.4 11.8 67.2 0.0 2.3 2.3 2.5 3.5 7.8 4.7 0.4 0.2 87.0 59.9 1.2 4.4 0.3 0.3 0.0 3.9 10.1 2.2 19.9 0.0 15.9 0.0 0.0 3.0 0.0 47.3 0.0 0.0 3.8 36.8 0.0 0.0 5.5 0.0 2.3 12.7 0.0 3.1 6.5 5.1 6.2 5.8 5.7 6.6 15.7 11.5 17.2 12.1 10.4 19.1 14.0 57.7 28.8 1364.3 142.1 8.2 3.9 35.6 10.2 6.6 1.2 4.7 26.4 47.1 18.3 46.0 6.2 54.8 9.9 1.0 226.9 9.4 30.5 1.2 12.9 9.5 2.4 0.0 12.2 11.8 26.2 24.7 25.0 1.4 1.3 6.7 4.2 9.5 10.5 111.0 51.3 3.3 6.1 33.7 21.3 8.8 16.8 26.3 19.6 905.0 34.0 27.7 0.0 27.2 21.8 7.4 2.9 12.4 2.0 2.3 0.2 205.9 24.8 6.6 6.6 50.0 21.3 8.1 5.9 4.0 6.3 232.9 4.1 18.4 5.0 1.9 ARHGAP45 "HA-1, HMHA1, KIAA0223" ENSG00000180448 "Rho GTPase activating protein 45" Q92619 19 1065923-1086628 "Plasma proteins, Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 68.3;intestine: 53.2;lung: 39.5;lymphoid tissue: 106.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 48.1;Cytotrophoblasts: 40.1;dendritic cells: 62.7;Extravillous trophoblasts: 56.6;Hofbauer cells: 40.0;monocytes: 72.4;Syncytiotrophoblasts: 75.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 73.7;Karpas-707: 100.4;RPMI-8226: 74.7;THP-1: 92.3;U-266/70: 130.8;U-937: 72.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019816, HPA079252" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA019816: AB_1853923, HPA079252: " "unprognostic (1.34e-1)" "unprognostic (5.13e-3)" "unprognostic (5.17e-3)" "prognostic favorable (6.02e-4)" "unprognostic (2.26e-1)" "prognostic favorable (7.82e-4)" "unprognostic (1.59e-2)" "unprognostic (2.17e-2)" "unprognostic (3.55e-1)" "unprognostic (4.78e-2)" "unprognostic (2.43e-1)" "unprognostic (2.05e-2)" "unprognostic (1.00e-1)" "unprognostic (4.59e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (5.33e-2)" 11.2 5.5 3.6 43.1 3.4 68.3 5.5 4.4 7.5 4.2 5.1 12.4 7.2 3.5 0.5 5.5 6.7 5.0 4.4 3.3 4.4 7.8 7.4 39.5 58.4 9.1 5.4 2.0 2.7 0.8 4.5 6.0 6.9 5.9 2.6 8.7 6.4 1.5 2.1 3.9 53.2 2.2 7.6 106.1 10.9 3.5 8.1 32.9 9.0 0.8 18.6 6.6 5.5 11.4 11.2 2.1 0.1 12.1 0.0 0.0 27.8 0.1 0.0 0.0 0.0 29.2 13.9 73.7 3.0 0.0 0.4 9.6 2.1 0.6 0.0 54.7 1.0 10.1 22.6 3.5 0.4 48.6 56.2 0.0 2.9 0.1 0.0 0.0 0.1 46.8 6.8 100.4 0.0 0.6 54.5 43.4 7.6 1.9 5.4 52.0 0.3 74.7 0.0 0.2 0.6 0.2 16.8 0.0 4.5 0.7 3.5 92.3 4.8 0.2 1.9 0.2 0.3 130.8 60.2 58.8 0.3 72.1 5.4 6.7 24.4 25.3 45.7 21.2 38.8 15.9 52.2 54.1 22.5 18.3 68.9 53.6 37.0 28.0 20.9 13.3 43.5 59.8 3.6 3.4 4.4 7.5 3.3 4.4 9.1 5.4 6.9 7.6 8.1 11.4 2.0 48.1 8.4 0.0 17.8 0.0 0.0 0.0 0.0 0.0 15.2 11.0 0.0 0.0 1.8 11.0 0.0 40.1 62.7 0.0 0.0 2.6 0.0 4.5 0.7 1.6 0.0 0.0 0.0 3.8 56.6 1.3 0.0 3.5 3.8 0.2 0.0 0.0 40.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.0 0.0 0.0 72.4 0.0 0.0 0.0 0.0 7.8 0.0 0.0 15.2 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 75.5 30.2 0.1 0.0 0.0 ARHGAP9 "10C, MGC1295" ENSG00000123329 "Rho GTPase activating protein 9" Q9BRR9 12 57472264-57488814 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 119.7;lymphoid tissue: 100.7" "Cell type enhanced" "Detected in many" "dendritic cells: 171.0;Early spermatids: 96.8;NK-cells: 123.6;Spermatocytes: 89.0;T-cells: 108.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 388.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 27.6;HMC-1: 116.2;MOLT-4: 22.5;NB-4: 22.1;THP-1: 34.9;U-937: 27.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" HPA078822 Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Cell Junctions" "HPA078822: " "unprognostic (1.02e-2)" "unprognostic (4.01e-3)" "unprognostic (1.91e-2)" "prognostic favorable (6.61e-5)" "unprognostic (1.24e-1)" "unprognostic (2.38e-3)" "unprognostic (4.79e-2)" "unprognostic (5.56e-3)" "unprognostic (1.28e-2)" "unprognostic (2.80e-1)" "unprognostic (3.05e-2)" "unprognostic (3.64e-1)" "prognostic unfavorable (7.90e-9)" "unprognostic (1.60e-1)" "unprognostic (6.32e-2)" "unprognostic (9.13e-2)" "unprognostic (6.91e-2)" 10.8 4.2 4.2 34.3 6.1 119.7 4.1 8.1 11.1 2.6 4.7 7.7 8.2 3.4 1.6 4.6 7.4 10.5 3.9 4.4 5.3 5.1 7.5 22.0 56.9 7.8 5.8 1.6 3.5 0.6 2.2 5.2 8.8 4.3 10.7 0.5 4.7 1.8 1.3 2.2 37.6 5.9 5.6 100.7 8.8 19.3 6.1 34.9 4.5 6.4 60.7 9.5 3.6 6.4 0.2 0.0 0.2 0.5 0.0 0.0 0.1 0.4 0.5 0.1 0.2 0.1 0.0 14.3 0.3 0.3 0.0 0.2 0.4 0.0 0.0 0.7 0.0 27.6 0.1 0.0 1.1 16.4 116.2 0.7 0.0 0.0 0.3 0.2 0.0 14.3 0.5 7.9 0.0 0.0 22.5 22.1 1.0 0.0 0.0 9.1 10.2 4.6 0.0 0.1 3.9 3.0 0.0 0.0 0.4 0.5 0.0 34.9 0.9 0.2 0.3 0.1 0.1 9.2 7.2 13.3 0.3 27.3 0.5 51.9 86.1 243.4 43.3 89.2 30.0 35.9 47.3 39.6 72.1 44.0 61.9 46.0 388.9 68.2 71.0 97.4 63.6 70.8 4.2 6.1 8.1 11.1 4.4 5.3 7.8 5.8 8.8 5.6 6.1 6.4 2.2 0.0 14.2 1.0 49.1 1.5 0.2 0.0 1.8 0.2 1.6 2.9 2.1 1.5 1.3 0.0 2.1 0.4 171.0 0.6 0.0 0.2 96.8 0.6 0.8 1.5 0.0 11.6 3.7 0.0 0.6 2.4 4.6 0.8 12.0 0.0 3.6 1.2 43.5 0.0 1.9 0.5 0.0 39.0 19.7 44.8 1.8 35.1 0.0 8.4 34.8 0.0 123.6 0.0 0.2 0.2 0.1 0.0 50.8 0.2 0.0 0.3 2.2 0.7 0.0 0.6 1.2 89.0 17.5 0.4 1.4 0.3 108.2 0.3 0.4 0.1 ARHGDIG RHOGDI-3 ENSG00000242173 "Rho GDP dissociation inhibitor gamma" Q99819 16 280450-283010 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 249.4;pancreas: 112.7" "Cell type enhanced" "Detected in some" "Astrocytes: 12.1;Excitatory neurons: 27.8;Inhibitory neurons: 32.1;Proximal enterocytes: 64.0" "Cancer enhanced" "Detected in many" "glioma: 3.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.6;HEK 293: 26.6;MCF7: 34.9;SCLC-21H: 10.9;SH-SY5Y: 13.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA078260 Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA078260: AB_2732375" "unprognostic (1.11e-2)" "unprognostic (5.69e-2)" "unprognostic (7.98e-2)" "unprognostic (2.66e-2)" "unprognostic (9.04e-2)" "unprognostic (2.13e-2)" "unprognostic (1.49e-1)" "unprognostic (2.75e-1)" "unprognostic (1.22e-1)" "unprognostic (1.44e-2)" "unprognostic (3.18e-1)" "unprognostic (2.94e-1)" "unprognostic (5.86e-6)" "unprognostic (2.81e-2)" "unprognostic (4.34e-1)" "unprognostic (2.15e-1)" "unprognostic (6.32e-2)" 4.5 2.8 116.5 1.1 138.7 0.2 1.3 118.2 249.4 0.5 49.9 5.9 16.7 0.1 0.9 0.5 0.5 0.1 10.2 130.1 121.2 0.3 0.2 0.5 0.0 110.3 106.1 0.3 112.7 0.6 10.1 2.2 109.8 0.9 0.4 4.0 0.4 0.3 1.9 0.2 6.9 0.6 84.9 0.1 26.8 3.6 112.6 0.0 0.3 1.4 0.4 0.4 1.1 134.9 0.0 0.8 0.2 2.9 0.0 0.4 0.0 0.1 0.0 0.4 0.0 0.4 0.1 0.0 0.9 0.1 0.0 0.1 7.6 0.0 0.0 0.0 26.6 0.0 0.4 0.2 0.7 0.0 0.1 0.2 0.0 0.0 0.0 1.3 0.3 0.0 1.8 0.1 0.0 34.9 0.0 0.0 3.1 1.6 0.0 0.0 0.0 0.3 0.0 0.0 10.9 13.9 0.2 0.1 0.0 0.4 2.6 0.0 0.3 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 116.5 138.7 118.2 249.4 130.1 121.2 110.3 106.1 109.8 84.9 112.6 134.9 0.1 0.0 0.0 12.1 0.0 0.4 0.0 0.0 0.0 4.0 0.0 0.3 1.4 0.0 0.0 0.0 2.1 0.1 0.0 0.7 0.0 0.2 0.4 0.0 0.4 0.1 1.2 2.7 27.8 11.7 0.2 2.5 6.1 0.0 0.0 0.2 1.4 0.0 0.4 0.0 32.1 3.7 0.0 0.0 0.0 0.6 0.3 0.0 0.0 8.4 0.0 2.2 0.0 6.6 10.9 3.9 3.9 0.0 0.0 0.1 64.0 0.1 0.0 3.7 0.0 0.0 0.4 0.2 3.9 0.0 0.0 0.4 0.0 0.0 7.0 0.1 ARHGEF1 "LBCL2, P115-RHOGEF, SUB1.5" ENSG00000076928 "Rho guanine nucleotide exchange factor 1" Q92888 19 41883173-41930150 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.4" "Cell type enhanced" "Detected in all" "dendritic cells: 156.2;NK-cells: 187.4;T-cells: 159.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009502, HPA012924, HPA060784" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB009502: AB_667785, HPA012924: AB_1845000, HPA060784: AB_2684363" "prognostic favorable (5.92e-4)" "unprognostic (2.09e-1)" "unprognostic (8.29e-3)" "unprognostic (8.10e-3)" "unprognostic (7.63e-2)" "unprognostic (7.59e-3)" "unprognostic (4.99e-2)" "unprognostic (7.28e-2)" "unprognostic (5.88e-2)" "unprognostic (1.84e-2)" "unprognostic (6.59e-2)" "unprognostic (3.29e-3)" "prognostic unfavorable (3.36e-8)" "unprognostic (3.54e-1)" "unprognostic (1.95e-1)" "unprognostic (8.00e-2)" "unprognostic (4.65e-2)" 50.2 20.9 17.1 79.1 21.8 113.5 39.9 19.1 21.9 37.2 17.8 37.5 26.8 33.4 3.6 34.1 36.4 23.5 26.2 16.1 18.2 31.9 30.0 67.7 127.5 24.1 20.2 32.9 27.4 12.6 25.9 18.3 22.0 32.1 10.4 5.6 28.8 11.8 15.4 37.6 87.1 13.4 19.0 168.4 34.9 10.9 21.4 96.5 36.7 8.9 48.9 33.9 33.2 27.9 58.8 69.9 15.8 19.9 21.9 22.9 18.4 30.1 45.7 37.4 32.8 21.5 49.2 77.9 54.6 27.8 19.8 33.8 20.3 46.9 11.8 74.1 23.6 63.1 30.6 28.4 31.9 68.4 100.8 27.8 30.5 36.3 23.5 19.9 36.2 68.2 25.5 46.7 21.8 40.4 48.0 52.9 17.9 46.4 54.0 71.8 29.7 46.3 23.2 31.8 10.3 43.8 42.3 18.7 36.0 8.1 21.9 114.4 49.6 49.7 33.2 26.8 47.7 63.0 43.2 68.4 40.5 107.6 80.2 10.4 20.5 29.2 47.0 39.5 37.2 20.1 35.6 49.4 21.5 19.5 36.1 39.4 27.4 32.1 57.5 11.3 38.7 36.4 17.1 21.8 19.1 21.9 16.1 18.2 24.1 20.2 22.0 19.0 21.4 27.9 46.6 6.4 22.0 35.3 97.3 14.5 13.9 15.0 20.5 18.7 13.1 12.4 4.2 8.6 8.8 7.3 27.1 13.3 156.2 21.7 3.9 23.6 1.4 12.2 16.7 29.0 21.7 23.8 8.0 24.9 22.8 17.7 56.6 16.8 31.7 19.3 26.7 9.3 38.2 11.8 7.9 29.2 16.2 52.5 31.9 1.8 19.3 58.9 19.6 18.7 39.0 8.8 187.4 13.6 27.6 55.9 22.7 16.6 66.4 15.7 10.1 7.3 6.3 19.1 26.3 17.6 17.3 7.3 10.1 17.3 14.8 10.1 159.0 20.4 26.4 11.1 ARHGEF11 "GTRAP48, KIAA0380, PDZ-RHOGEF" ENSG00000132694 "Rho guanine nucleotide exchange factor 11" O15085 1 156934840-157045742 "Predicted intracellular proteins" "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 68.6;Cone photoreceptor cells: 93.8;Excitatory neurons: 102.4;Inhibitory neurons: 122.5;Oligodendrocyte precursor cells: 78.4;Rod photoreceptor cells: 58.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "WM-115: 69.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011026, HPA012037, HPA014658" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA011026: AB_1850426, HPA012037: AB_1850430, HPA014658: AB_1850428" "unprognostic (2.19e-1)" "unprognostic (9.10e-2)" "unprognostic (1.91e-1)" "unprognostic (2.17e-1)" "unprognostic (2.00e-1)" "unprognostic (4.94e-3)" "unprognostic (3.30e-2)" "unprognostic (9.40e-2)" "unprognostic (1.21e-1)" "unprognostic (1.58e-1)" "prognostic favorable (1.72e-4)" "unprognostic (3.38e-1)" "unprognostic (2.41e-2)" "unprognostic (5.11e-2)" "unprognostic (1.58e-1)" "unprognostic (1.08e-1)" "unprognostic (4.73e-2)" 10.9 10.9 10.3 9.5 8.6 4.3 8.1 4.1 22.6 10.0 0.8 12.3 13.1 12.0 9.6 11.5 10.3 10.2 12.1 9.4 10.2 7.2 6.3 11.4 5.3 12.7 11.1 13.2 9.9 25.0 12.2 11.1 12.0 9.2 11.2 17.6 8.6 11.6 12.3 10.0 14.9 13.3 4.0 9.3 10.7 19.2 16.9 3.6 13.0 11.2 5.7 10.4 8.1 11.1 13.5 26.6 22.0 16.9 28.5 14.6 25.0 13.4 19.4 20.0 14.6 17.9 14.0 1.8 22.6 23.0 15.3 14.4 15.0 13.5 10.8 19.6 9.3 6.7 15.9 11.5 16.4 13.7 23.0 22.7 14.4 18.3 14.2 14.9 14.5 5.7 11.1 1.2 13.3 17.4 3.5 7.2 27.6 21.0 16.0 0.5 10.9 7.4 9.5 21.9 4.2 25.1 28.3 22.6 23.3 18.8 20.3 30.3 22.4 20.6 12.9 18.3 13.7 18.7 12.2 1.3 13.1 1.8 69.7 0.0 0.4 0.0 0.0 0.8 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.9 0.0 0.4 0.0 0.0 0.2 10.3 8.6 4.1 22.6 9.4 10.2 12.7 11.1 12.0 4.0 16.9 11.1 6.2 3.2 4.2 68.6 0.5 1.1 2.8 0.4 0.0 48.0 5.0 5.8 15.3 7.2 1.6 1.8 93.8 1.8 0.0 26.0 1.9 1.1 8.6 7.7 10.9 5.0 5.4 0.4 102.4 1.6 0.6 5.5 10.2 7.8 8.9 6.6 5.3 5.2 4.0 21.9 122.5 7.3 0.0 8.8 3.9 10.5 4.7 7.1 1.8 37.5 6.8 9.7 0.0 78.4 47.2 1.2 10.8 4.5 2.9 4.0 10.6 1.3 1.4 58.7 0.0 6.7 6.9 3.1 4.8 1.8 2.0 1.5 0.9 9.2 9.8 3.3 ARHGEF40 "FLJ10357, solo" ENSG00000165801 "Rho guanine nucleotide exchange factor 40" Q8TER5 14 21070273-21090248 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 6.2" "Lineage enriched" "Detected in many" 6 "granulocytes: 6.2" "Cell line enhanced" "Detected in many" "ASC TERT1: 37.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030745, HPA030746, HPA030757" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA030745: , HPA030746: AB_10599613, HPA030757: AB_10600203" "unprognostic (6.30e-2)" "unprognostic (1.94e-1)" "unprognostic (2.36e-1)" "unprognostic (5.91e-2)" "unprognostic (2.55e-1)" "unprognostic (8.16e-3)" "unprognostic (1.27e-2)" "unprognostic (9.84e-3)" "unprognostic (1.33e-1)" "unprognostic (8.80e-2)" "unprognostic (1.64e-2)" "unprognostic (2.53e-1)" "unprognostic (6.01e-3)" "unprognostic (1.14e-2)" "unprognostic (1.38e-2)" "unprognostic (2.33e-1)" "unprognostic (8.95e-2)" 21.0 47.2 9.6 5.3 11.1 1.6 18.5 10.0 9.2 24.8 6.2 14.5 3.7 18.9 12.2 3.5 13.2 14.8 12.3 8.9 11.1 10.1 26.9 14.2 2.3 13.5 10.5 19.3 24.0 10.7 9.0 6.5 10.5 12.3 6.2 2.8 20.2 18.6 10.5 7.4 7.9 9.7 10.1 27.8 9.5 4.3 12.1 3.1 15.8 6.1 1.7 13.8 13.3 12.1 3.3 2.9 30.8 5.8 24.5 37.1 1.1 11.4 28.1 12.1 9.4 1.4 7.5 0.0 1.8 20.9 12.2 5.0 2.6 3.7 4.3 6.6 1.1 4.6 3.4 9.0 3.5 3.0 16.5 15.5 2.4 10.3 3.1 22.6 0.0 0.0 1.4 1.3 9.6 0.3 0.0 8.6 8.1 0.8 0.5 1.0 23.2 1.4 7.6 4.1 0.7 11.6 6.4 0.6 8.9 6.0 2.7 10.1 5.9 25.4 17.5 11.9 5.9 2.6 0.0 0.0 8.8 4.2 7.5 0.0 1.0 2.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 6.2 0.1 0.0 0.1 0.0 0.4 9.6 11.1 10.0 9.2 8.9 11.1 13.5 10.5 10.5 10.1 12.1 12.1 12.7 6.4 5.0 32.0 2.5 4.8 8.0 5.8 1.8 9.2 6.6 11.3 13.4 47.1 3.2 14.7 0.0 1.4 0.5 10.0 19.6 21.2 1.0 17.6 13.1 11.0 7.8 1.7 0.3 10.2 0.9 20.4 18.3 3.5 38.0 11.6 8.2 31.5 14.1 5.0 6.2 9.1 4.1 46.9 14.6 2.3 24.2 22.0 23.2 17.8 23.6 24.6 1.0 21.1 8.9 16.4 6.6 24.0 3.1 6.3 1.0 7.1 1.7 6.8 26.3 18.6 21.9 3.1 2.8 0.6 4.4 1.2 3.5 14.6 18.7 6.1 ARID2 "BAF200, DKFZp686G052, FLJ30619, KIAA1557" ENSG00000189079 "AT-rich interaction domain 2" Q68CP9 12 45729706-45908040 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 525.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063044 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA063044: AB_2684929" "unprognostic (8.41e-2)" "unprognostic (1.03e-1)" "unprognostic (4.02e-2)" "unprognostic (3.94e-2)" "unprognostic (4.15e-2)" "prognostic favorable (5.75e-4)" "unprognostic (1.26e-2)" "unprognostic (9.71e-2)" "unprognostic (9.04e-2)" "unprognostic (5.57e-2)" "unprognostic (1.34e-1)" "unprognostic (2.47e-1)" "unprognostic (1.12e-2)" "unprognostic (9.21e-2)" "unprognostic (3.02e-1)" "unprognostic (2.00e-1)" "unprognostic (6.53e-2)" 6.4 5.2 4.6 6.7 7.8 12.6 7.5 13.8 6.9 8.5 10.2 6.8 5.0 6.9 6.5 8.4 6.4 5.4 6.0 5.0 7.3 6.3 5.4 7.8 7.5 7.8 6.4 8.3 7.2 11.7 5.0 7.2 7.6 7.4 6.0 13.2 6.7 6.2 5.9 10.0 6.6 6.1 6.0 6.9 6.2 26.1 6.2 18.7 8.8 7.7 8.9 6.8 8.0 9.8 10.3 14.5 25.3 11.1 10.5 7.3 13.7 7.0 9.9 9.6 8.9 20.7 10.4 19.8 12.7 9.8 7.0 12.1 20.6 11.8 13.6 8.8 9.8 26.1 15.9 10.1 7.2 20.7 11.5 6.0 8.8 12.1 19.1 13.4 10.0 29.1 22.4 19.9 8.6 13.4 29.9 14.7 15.1 0.0 7.7 22.9 18.0 19.0 9.1 16.9 13.6 17.4 11.4 13.0 11.1 14.5 20.0 40.8 11.8 10.3 12.3 7.0 9.2 13.2 11.8 53.6 7.9 53.2 7.4 9.4 1.1 2.7 2.4 1.3 2.5 1.0 2.1 2.5 1.5 1.1 2.0 1.9 1.4 2.1 3.4 3.3 2.0 0.9 4.6 7.8 13.8 6.9 5.0 7.3 7.8 6.4 7.6 6.0 6.2 9.8 23.3 28.9 28.4 110.4 30.8 33.8 14.4 16.3 36.5 51.6 21.7 15.4 15.6 14.3 17.3 29.5 68.8 15.5 49.0 21.3 7.9 13.2 525.4 23.2 23.8 21.1 21.0 35.1 56.7 10.0 10.5 22.0 24.5 27.7 22.1 29.3 19.2 17.3 11.2 32.0 60.3 19.0 22.4 29.8 36.7 149.3 24.8 25.6 14.2 128.4 22.4 19.9 45.3 144.3 157.9 18.8 24.6 22.6 33.8 23.7 19.1 7.4 15.4 66.2 26.3 27.0 27.2 80.2 17.0 39.3 41.3 23.4 34.8 16.4 17.9 21.0 ARL4C "ARL7, LAK" ENSG00000188042 "ADP ribosylation factor like GTPase 4C" P56559 2 234493041-234497081 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 74.0" "Cell type enhanced" "Detected in many" "dendritic cells: 610.9;Langerhans cells: 474.5;NK-cells: 437.7;T-cells: 349.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 149.4;RPTEC TERT1: 284.8;U-2197: 168.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028927 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA028927: AB_10602387" "unprognostic (1.93e-1)" "unprognostic (1.14e-1)" "unprognostic (3.20e-3)" "prognostic unfavorable (2.90e-7)" "unprognostic (8.01e-3)" "unprognostic (3.35e-2)" "unprognostic (9.26e-2)" "unprognostic (2.68e-2)" "unprognostic (2.10e-1)" "unprognostic (4.34e-2)" "unprognostic (3.17e-3)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.69e-8)" "unprognostic (8.57e-2)" "unprognostic (4.64e-2)" "unprognostic (1.20e-1)" "prognostic unfavorable (6.99e-5)" 15.1 10.6 15.4 31.7 14.6 65.0 17.3 17.8 18.6 11.4 45.3 9.1 6.6 5.8 9.5 23.2 11.9 31.8 5.1 13.1 21.9 12.2 12.8 16.1 55.3 21.9 17.1 2.1 5.5 10.8 7.4 16.5 21.3 10.3 11.2 9.7 21.6 5.4 1.5 24.1 13.2 5.9 12.8 51.0 13.6 1.2 18.5 74.0 3.7 1.7 32.1 25.5 18.0 13.8 32.3 97.4 12.0 1.6 10.4 3.0 31.6 3.2 13.8 3.8 6.6 45.4 60.4 0.1 8.0 7.7 109.0 23.5 12.0 66.4 4.1 30.4 4.2 0.0 0.6 0.6 10.7 0.1 2.8 6.4 42.2 36.6 21.2 149.4 6.4 78.4 0.4 102.4 16.4 4.4 93.7 0.3 12.6 22.5 21.9 0.3 54.1 18.0 284.8 35.2 44.1 8.1 1.1 7.1 4.7 18.2 0.9 1.9 14.8 60.0 23.2 168.2 61.6 51.1 19.7 1.6 101.9 0.1 32.0 79.8 1.2 27.4 86.7 1.6 85.6 18.1 60.0 69.5 10.3 18.3 53.5 59.1 2.2 61.2 0.9 55.2 83.8 30.0 15.4 14.6 17.8 18.6 13.1 21.9 21.9 17.1 21.3 12.8 18.5 13.8 12.3 73.7 15.9 8.8 63.6 124.8 120.7 18.4 145.1 156.6 40.4 64.6 10.9 67.2 27.0 14.7 8.4 30.0 610.9 2.3 0.0 19.6 7.8 73.9 19.2 23.4 1.8 6.1 15.5 5.7 5.4 23.7 19.9 186.3 27.8 1.1 11.0 3.4 31.4 107.7 103.0 2.5 0.0 208.4 474.5 6.5 0.3 182.1 42.7 6.5 41.8 32.2 437.7 6.0 2.5 16.5 0.1 0.0 132.6 60.4 0.1 0.9 4.7 13.1 0.0 7.0 19.3 0.7 1.9 65.4 42.9 14.6 349.8 0.4 1.2 46.6 ARMC12 "C6orf81, FLJ25390" ENSG00000157343 "Armadillo repeat containing 12" Q5T9G4 6 35737032-35749079 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 64.2" "Group enriched" "Detected in some" 96 "Early spermatids: 503.3;Late spermatids: 1116.3" "Cancer enhanced" "Detected in some" "glioma: 1.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 4.9;HSkMC: 6.1;MOLT-4: 4.8;U-698: 5.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA030895, HPA075457, HPA075777" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 34: Spermatids - Unknown function" "Nucleoplasm, Plasma membrane" "HPA030895: AB_10602114, HPA075457: , HPA075777: " "unprognostic (1.94e-4)" "unprognostic (2.21e-1)" "unprognostic (3.24e-1)" "unprognostic (1.32e-2)" "unprognostic (2.34e-1)" "unprognostic (1.19e-1)" "unprognostic (2.52e-1)" "unprognostic (2.12e-1)" "unprognostic (4.48e-1)" "unprognostic (3.52e-2)" "unprognostic (6.36e-4)" "unprognostic (8.99e-2)" "unprognostic (1.17e-12)" "unprognostic (6.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.49e-1)" "unprognostic (2.09e-1)" 1.6 1.7 4.4 0.6 4.4 0.9 1.5 4.0 5.3 2.5 5.1 1.5 0.0 1.7 5.8 0.8 2.8 0.7 0.7 4.3 4.5 1.5 4.5 1.2 1.3 4.6 5.1 3.0 1.3 0.5 11.2 0.2 4.6 3.6 0.3 1.3 0.6 0.8 1.9 1.1 1.7 0.7 4.3 2.8 1.2 64.2 4.3 3.0 2.4 0.5 0.7 1.1 1.7 4.5 0.0 0.3 2.1 2.7 4.9 2.3 0.0 0.1 0.1 0.2 0.2 0.0 0.1 0.5 0.1 0.1 0.8 0.1 0.6 0.1 0.1 1.2 0.6 0.3 0.1 0.0 2.4 0.0 0.0 6.1 1.5 0.1 0.9 2.5 0.5 2.0 0.0 3.2 0.8 0.3 4.8 0.6 0.4 0.0 0.1 2.2 0.0 0.0 0.5 0.0 0.6 2.0 0.0 0.0 0.4 1.0 1.4 0.2 0.0 0.4 0.2 0.1 0.0 0.7 0.2 5.4 0.2 2.8 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.2 0.0 0.2 0.9 0.0 0.0 0.0 0.8 0.0 0.1 4.4 4.4 4.0 5.3 4.3 4.5 4.6 5.1 4.6 4.3 4.3 4.5 0.8 0.0 0.0 4.6 0.1 0.9 1.9 0.2 1.2 0.0 0.3 0.4 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 503.3 0.4 0.4 0.8 0.0 0.4 0.3 0.0 0.0 0.6 0.0 0.3 0.0 2.4 0.4 2.8 0.0 0.0 0.5 0.2 0.0 1.2 0.8 1116.3 8.4 1.3 0.0 0.0 0.1 0.8 0.0 0.5 0.3 0.0 0.0 4.1 0.0 0.7 0.2 0.3 0.2 0.2 0.0 0.5 0.4 8.1 6.0 0.7 0.1 0.0 0.3 0.2 0.2 0.4 ARRDC4 FLJ36045 ENSG00000140450 "Arrestin domain containing 4" Q8NCT1 15 97960703-97973833 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 82.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 105.7;Paneth cells: 82.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 1.1;classical monocyte: 2.5;eosinophil: 1.5;intermediate monocyte: 1.7;myeloid DC: 1.1;neutrophil: 1.4" "Group enriched" "Detected in many" 8 "dendritic cells: 1.1;granulocytes: 1.5;monocytes: 2.5" "Cell line enhanced" "Detected in many" "BJ: 103.2;HSkMC: 55.8;hTCEpi: 86.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039934, HPA042109" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Vesicles "HPA039934: , HPA042109: AB_10795606" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.32e-1)" "unprognostic (5.60e-3)" "unprognostic (4.49e-3)" "unprognostic (8.23e-2)" "unprognostic (1.16e-2)" "unprognostic (2.78e-1)" "unprognostic (7.65e-2)" "unprognostic (1.10e-1)" "unprognostic (1.01e-2)" "unprognostic (1.42e-2)" "unprognostic (2.02e-3)" "unprognostic (2.90e-2)" "unprognostic (1.65e-1)" "unprognostic (3.04e-2)" "unprognostic (6.77e-2)" 12.5 12.2 21.6 16.5 24.6 11.5 19.8 24.1 22.4 16.2 16.9 43.9 15.8 14.6 15.6 10.0 14.5 17.2 12.1 30.5 39.1 25.1 30.2 19.8 7.5 76.6 24.1 7.3 34.7 6.3 8.9 18.3 73.9 10.9 23.0 4.5 8.1 16.4 14.8 35.5 22.6 18.1 45.9 8.0 26.9 14.7 20.5 5.7 17.3 9.6 5.1 14.9 10.8 82.8 5.8 0.2 0.8 15.0 6.6 47.7 0.0 103.2 45.8 13.5 6.0 6.2 3.6 0.0 14.2 4.8 1.2 6.0 3.7 36.0 21.6 0.0 9.6 10.1 1.9 4.1 2.6 7.0 15.2 55.8 86.9 15.4 17.9 18.8 0.7 2.9 14.4 0.0 4.9 19.2 1.2 5.8 3.0 17.4 2.1 0.1 0.9 0.2 26.3 12.7 5.0 8.8 15.7 5.7 29.5 3.1 2.1 10.6 0.1 4.0 2.9 21.2 5.0 0.0 0.0 0.2 8.7 1.2 10.6 1.1 2.5 1.5 0.0 1.7 0.0 0.2 0.0 0.0 1.1 0.1 0.0 0.0 1.4 0.0 0.2 0.2 0.0 0.4 21.6 24.6 24.1 22.4 30.5 39.1 76.6 24.1 73.9 45.9 20.5 82.8 5.7 3.2 10.4 19.9 4.0 25.4 3.1 11.0 23.9 1.6 14.4 8.3 12.9 8.6 9.4 22.0 6.2 0.3 1.4 105.7 7.9 2.7 4.5 21.5 17.6 5.9 38.3 4.4 8.1 8.2 0.2 12.3 15.8 18.0 23.5 1.4 6.4 17.1 21.5 0.0 6.0 29.5 10.2 23.9 10.5 10.9 5.0 19.7 24.9 3.7 13.4 0.7 3.1 38.7 3.4 12.0 82.4 8.2 0.2 12.2 30.2 3.1 15.6 3.5 0.0 7.8 12.5 2.0 12.6 11.8 31.1 0.7 1.3 17.5 31.3 12.2 ARVCF ENSG00000099889 "ARVCF delta catenin family member" O00192 22 19969896-20016823 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 24.2;Cone photoreceptor cells: 22.9;Muller glia cells: 21.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 20.1;REH: 10.5;SCLC-21H: 18.0;SH-SY5Y: 13.8;U-2 OS: 15.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016162, HPA055264, HPA063675" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 1: K-562 - Erythropoiesis" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cell Junctions" "CAB016162: AB_2058690, HPA055264: AB_2682766, HPA063675: AB_2685085" "unprognostic (1.66e-1)" "unprognostic (1.48e-2)" "unprognostic (4.00e-2)" "unprognostic (4.28e-2)" "unprognostic (3.35e-1)" "unprognostic (3.18e-2)" "unprognostic (4.79e-3)" "unprognostic (1.67e-2)" "unprognostic (2.06e-2)" "unprognostic (1.71e-2)" "unprognostic (2.09e-3)" "unprognostic (5.77e-2)" "unprognostic (4.00e-3)" "unprognostic (9.84e-2)" "unprognostic (1.56e-1)" "unprognostic (1.15e-1)" "prognostic favorable (5.76e-6)" 3.8 3.1 6.4 0.7 5.4 3.2 4.4 18.4 6.2 4.3 1.2 5.9 1.0 4.8 3.2 1.3 3.5 1.3 6.4 5.6 7.1 6.2 6.8 4.5 0.5 7.0 5.2 3.5 5.1 1.7 9.4 1.0 5.7 5.7 0.3 1.4 7.0 1.7 7.4 4.7 2.8 0.7 4.9 10.8 4.8 4.9 8.3 0.2 15.6 1.2 0.1 2.8 2.8 5.1 4.1 0.4 5.5 7.1 0.1 0.0 5.6 1.0 0.4 0.3 0.6 1.1 0.9 1.7 4.5 0.5 0.5 3.8 0.9 1.8 0.0 0.5 6.8 0.5 0.5 4.4 1.6 0.6 1.3 0.1 0.7 0.3 0.2 0.3 4.5 1.3 20.1 0.6 0.1 3.8 0.3 2.6 5.6 1.3 2.3 10.5 0.3 0.5 0.9 0.9 18.0 13.8 1.1 1.7 2.7 0.9 1.5 0.5 1.7 0.1 15.6 0.7 0.3 2.2 0.7 0.5 0.2 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 6.4 5.4 18.4 6.2 5.6 7.1 7.0 5.2 5.7 4.9 8.3 5.1 2.3 3.2 2.6 24.2 0.7 2.0 3.0 4.4 0.6 9.7 6.6 7.9 6.0 5.7 3.2 1.8 22.9 5.6 2.3 1.8 0.0 8.9 2.7 2.4 0.9 3.0 9.0 4.0 4.7 5.5 2.2 2.4 1.5 4.5 0.0 4.7 2.5 4.1 1.4 5.0 6.2 7.0 10.2 1.0 1.2 1.7 4.1 0.8 3.6 5.6 0.0 21.7 7.2 8.0 1.8 10.7 0.6 3.4 0.9 4.7 0.8 5.6 4.9 8.6 0.0 7.7 6.2 2.3 8.4 0.4 1.8 4.4 0.6 1.6 2.1 1.5 ASGR2 CLEC4H2 ENSG00000161944 "Asialoglycoprotein receptor 2" P07307 17 7101322-7115700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Endocytosis, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 48 "liver: 840.7" "Cell type enriched" "Detected in some" 5 "Hepatocytes: 878.6" "Cancer enriched" "Detected in many" 66 "liver cancer: 214.2" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 8 "classical monocyte: 110.0;myeloid DC: 64.1" "Group enriched" "Detected in many" 51 "dendritic cells: 64.1;monocytes: 110.0" "Cell line enriched" "Detected in some" 9 "Hep G2: 528.3" "Not detected" "Not detected" "Not detected" "Not detected" "HPA014899, HPA015998" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA 14000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 15: Hepatocytes - Hemostasis" "Endoplasmic reticulum, Plasma membrane" "HPA014899: AB_1845085, HPA015998: AB_1845084" "unprognostic (6.76e-2)" "unprognostic (7.45e-7)" "unprognostic (1.61e-1)" "unprognostic (2.55e-2)" "unprognostic (1.03e-2)" "unprognostic (4.99e-2)" "unprognostic (1.16e-3)" "unprognostic (1.32e-1)" "unprognostic (1.81e-1)" "unprognostic (9.74e-2)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (9.35e-4)" "unprognostic (1.54e-3)" "unprognostic (6.95e-2)" "unprognostic (1.86e-1)" "unprognostic (7.31e-2)" 1.5 0.3 0.8 7.9 1.0 7.0 0.5 0.9 1.3 0.4 1.3 0.5 0.3 0.3 0.1 0.5 0.6 17.6 0.5 0.8 1.0 1.2 840.7 2.5 0.9 1.0 1.1 0.2 0.5 0.1 0.2 0.5 1.2 0.4 0.4 0.0 0.5 0.2 0.2 5.2 0.6 1.3 1.0 6.8 0.5 0.5 1.4 0.5 0.3 0.1 1.0 2.0 0.4 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 62.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.2 528.3 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 42.3 0.1 0.0 0.0 0.1 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.0 110.0 0.8 0.1 11.2 0.2 0.0 0.0 0.0 64.1 0.0 0.1 0.0 1.7 0.1 0.1 1.6 0.3 31.8 0.8 1.0 0.9 1.3 0.8 1.0 1.0 1.1 1.2 1.0 1.4 1.2 0.0 0.0 5.1 0.3 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 150.2 0.0 0.0 0.0 0.1 0.0 0.1 1.9 0.0 0.4 0.0 0.0 1.3 7.1 19.6 1.9 0.0 0.2 0.1 0.0 0.1 2.5 0.0 16.1 878.6 8.4 0.0 0.1 0.1 0.0 41.1 7.7 0.7 0.0 19.6 0.0 0.0 15.3 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 6.6 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.3 0.4 1.4 0.0 0.0 0.1 ASH2L "ASH2, ASH2L1, ASH2L2, Bre2" ENSG00000129691 "ASH2 like, histone lysine methyltransferase complex subunit" Q9UBL3 8 38105493-38144076 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, DNA-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Spermatocytes: 69.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HEL: 200.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042289 Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 2: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 36: HEL - Hemostasis" "Cluster 66: Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042289: AB_10795608" "unprognostic (9.39e-2)" "unprognostic (5.58e-3)" "unprognostic (2.67e-3)" "unprognostic (5.40e-3)" "unprognostic (2.87e-1)" "unprognostic (2.66e-2)" "unprognostic (4.04e-1)" "unprognostic (9.15e-2)" "unprognostic (1.30e-1)" "unprognostic (1.12e-1)" "unprognostic (5.10e-2)" "unprognostic (9.73e-3)" "prognostic favorable (4.25e-4)" "unprognostic (9.95e-2)" "unprognostic (1.27e-1)" "unprognostic (7.69e-3)" "unprognostic (2.54e-1)" 28.9 18.9 19.7 17.9 20.3 31.6 21.4 19.2 21.5 19.9 14.7 22.5 18.2 22.0 17.1 23.8 20.1 17.4 21.3 20.2 17.4 23.3 23.6 18.5 27.9 16.7 16.1 26.2 17.7 24.8 12.0 22.1 16.7 19.9 22.3 21.7 20.6 21.0 32.4 20.4 18.3 24.2 16.5 18.9 22.1 41.3 19.0 33.6 21.1 27.7 28.3 18.5 16.1 18.1 45.6 23.3 39.8 39.8 26.3 34.0 49.8 44.1 45.7 53.5 47.0 24.9 21.1 51.4 38.2 37.1 27.2 27.5 49.0 24.8 50.4 20.3 22.4 200.3 22.9 51.7 39.4 32.0 41.3 28.6 22.9 25.0 27.7 28.1 43.9 48.0 138.2 40.0 53.7 26.1 91.9 40.7 51.7 39.3 15.6 38.2 42.9 23.4 28.9 33.1 18.3 32.4 33.5 22.5 38.4 37.1 27.4 40.4 33.5 35.3 35.0 50.4 37.6 37.8 48.7 44.9 35.2 44.7 49.7 39.9 23.0 55.9 16.8 26.8 18.1 19.6 18.8 20.0 27.7 19.2 19.3 18.4 19.2 26.1 25.8 15.8 21.3 21.6 19.7 20.3 19.2 21.5 20.2 17.4 16.7 16.1 16.7 16.5 19.0 18.1 11.1 12.8 15.8 18.3 14.3 6.9 9.3 13.3 10.8 12.9 9.6 8.0 18.1 8.6 15.9 12.9 10.4 37.0 15.9 11.5 7.9 21.2 10.8 12.7 13.2 14.0 10.8 62.1 19.7 28.7 37.2 17.3 8.6 10.8 19.6 38.2 12.8 11.9 24.2 6.7 21.4 11.6 12.2 17.2 5.7 13.0 23.3 17.0 23.2 15.9 29.2 17.8 19.6 17.6 16.5 21.3 8.9 20.7 8.4 6.2 12.8 17.1 18.0 15.5 13.1 14.6 20.7 69.6 33.9 11.6 6.8 30.9 11.9 37.3 10.9 7.4 ASIC1 "ACCN2, BNaC2, hBNaC2" ENSG00000110881 "Acid sensing ion channel subunit 1" P78348 12 50057548-50083611 "Predicted membrane proteins" "Calcium transport, Ion transport, Sodium transport, Transport" "Ion channel, Sodium channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.9" "Cell type enhanced" "Detected in some" "Astrocytes: 31.3;Inhibitory neurons: 16.4;Oligodendrocyte precursor cells: 64.8;Oligodendrocytes: 11.2" "Cancer enhanced" "Detected in many" "glioma: 12.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 34.8;SH-SY5Y: 27.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA058870 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 68: Oligodendrocytes - Mixed function" "Golgi apparatus, Plasma membrane" "HPA058870: AB_2683841" "unprognostic (5.32e-3)" "unprognostic (1.70e-1)" "unprognostic (4.00e-2)" "unprognostic (3.56e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-3)" "unprognostic (2.92e-3)" "unprognostic (3.00e-2)" "unprognostic (1.72e-1)" "unprognostic (9.37e-2)" "unprognostic (2.34e-2)" "unprognostic (2.86e-3)" "unprognostic (6.97e-7)" "unprognostic (7.19e-2)" "unprognostic (3.73e-1)" "unprognostic (2.78e-3)" "unprognostic (8.27e-5)" 1.6 0.7 19.3 0.9 22.2 0.1 1.6 14.4 19.8 3.2 6.4 6.3 0.8 1.9 0.0 2.3 3.0 2.5 2.6 18.2 21.0 0.7 0.2 0.6 0.4 18.0 24.9 1.1 0.5 5.0 0.8 0.6 15.9 2.8 1.2 1.0 3.5 1.9 0.3 0.9 2.5 2.3 13.7 0.3 2.8 0.7 23.7 1.5 0.5 0.0 0.2 1.9 1.7 13.8 3.3 7.2 8.7 19.7 2.7 4.2 4.9 2.2 6.1 4.0 4.0 4.8 2.3 2.1 4.7 1.1 2.4 3.2 8.7 7.7 2.3 1.9 25.1 6.2 9.0 3.2 3.8 9.5 22.7 10.7 3.7 0.4 1.0 34.8 0.5 22.8 4.3 0.0 3.3 4.0 8.8 18.3 3.9 6.9 12.5 9.3 8.5 4.0 2.0 0.1 13.4 27.4 5.3 1.8 3.2 1.4 11.0 6.5 0.3 4.1 12.8 2.5 1.2 0.1 0.0 0.0 5.1 7.6 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 22.2 14.4 19.8 18.2 21.0 18.0 24.9 15.9 13.7 23.7 13.8 0.3 0.0 0.0 31.3 0.0 0.0 0.4 0.5 0.0 2.8 2.0 2.8 0.9 0.0 2.1 1.8 0.0 0.4 0.1 0.1 0.0 0.2 0.1 0.0 0.7 0.1 0.0 0.0 7.0 0.0 0.9 3.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 3.3 16.4 0.1 0.0 0.0 0.3 0.0 1.5 0.1 0.0 1.9 0.0 1.4 0.0 64.8 11.2 0.2 0.0 1.2 0.2 0.5 0.0 3.2 6.0 0.5 0.0 1.3 0.7 0.1 0.9 2.3 0.0 0.3 0.9 0.4 0.0 0.2 ASPM "ASP, Calmbp1, FLJ10517, FLJ10549, MCPH5" ENSG00000066279 "Assembly factor for spindle microtubules" Q8IZT6 1 197084121-197146694 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Calmodulin-binding "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "bone marrow: 10.1;lymphoid tissue: 17.0" "Cell type enhanced" "Detected in many" "Erythroid cells: 99.5;Granulosa cells: 121.1;Plasma cells: 44.8;Spermatocytes: 43.8;Spermatogonia: 44.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Not detected" "Not detected" CAB017816 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB017816: " "unprognostic (3.24e-1)" "unprognostic (1.56e-1)" "unprognostic (2.81e-2)" "prognostic unfavorable (1.97e-4)" "unprognostic (3.67e-1)" "unprognostic (3.47e-2)" "prognostic unfavorable (1.25e-4)" "prognostic unfavorable (2.41e-4)" "unprognostic (4.67e-3)" "unprognostic (9.29e-2)" "prognostic unfavorable (2.40e-4)" "unprognostic (1.03e-1)" "unprognostic (0.00e+0)" "unprognostic (7.31e-3)" "unprognostic (1.23e-1)" "unprognostic (4.94e-2)" "unprognostic (3.66e-2)" 0.2 0.1 0.0 3.0 0.0 10.1 0.4 0.0 0.1 0.2 0.0 1.6 2.1 0.3 0.0 1.5 0.0 0.3 0.1 0.0 0.0 0.0 0.6 0.3 5.3 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 1.9 0.0 0.2 0.0 0.0 2.7 1.9 0.7 0.0 0.9 1.1 3.2 0.1 17.0 0.1 0.0 5.1 0.6 0.4 0.2 44.6 22.9 39.1 23.2 1.9 5.5 14.7 35.1 23.2 32.6 25.6 16.7 31.1 45.4 12.5 27.5 13.8 40.2 33.6 12.1 39.1 41.8 25.4 33.1 56.1 12.8 0.4 51.9 20.5 0.6 1.0 26.1 15.2 7.3 31.5 32.9 41.8 50.7 29.0 16.0 40.6 10.3 17.8 24.8 6.4 30.2 55.5 31.7 7.4 11.4 20.4 29.5 50.6 20.6 9.5 20.8 26.9 12.7 28.9 20.9 20.0 34.9 61.2 13.9 21.6 26.8 14.9 11.0 42.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.6 0.0 1.1 1.3 5.8 6.1 1.5 4.0 2.2 0.1 2.4 2.4 1.1 0.0 1.3 1.8 0.0 20.0 7.8 7.7 0.0 0.3 3.9 2.9 6.2 4.3 0.0 99.5 2.0 0.0 14.8 9.8 13.3 8.1 1.3 121.1 6.4 2.2 11.6 0.0 4.8 6.8 4.1 6.4 2.4 4.5 0.6 6.4 0.0 0.0 0.9 0.7 4.1 0.0 1.0 0.5 0.2 1.5 44.8 2.0 0.4 0.4 0.8 0.3 0.0 0.6 7.0 43.8 44.7 27.1 3.4 3.7 9.1 5.7 16.9 2.1 ATG3 "APG3L, DKFZp564M1178, FLJ22125, MGC15201, PC3-96" ENSG00000144848 "Autophagy related 3" Q9NT62 3 112532510-112562046 "Predicted intracellular proteins, Transporters" "Autophagy, Protein transport, Transport, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 657.9;Spermatocytes: 341.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037260, HPA040471" Enhanced Supported "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB037260: AB_1078236, HPA040471: AB_2677000" "unprognostic (2.77e-2)" "prognostic favorable (6.82e-4)" "unprognostic (4.90e-3)" "unprognostic (1.30e-1)" "unprognostic (2.63e-1)" "unprognostic (1.44e-1)" "prognostic unfavorable (9.35e-6)" "unprognostic (6.79e-2)" "unprognostic (6.67e-2)" "unprognostic (6.99e-2)" "unprognostic (2.56e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.52e-3)" "unprognostic (4.66e-2)" "unprognostic (6.02e-2)" "unprognostic (3.48e-2)" "unprognostic (5.25e-2)" 33.1 38.7 41.4 49.1 50.1 94.1 34.7 51.3 53.5 28.3 38.2 38.2 38.2 24.7 24.7 34.8 23.2 24.7 33.3 39.7 46.8 41.6 43.3 31.1 48.4 49.1 48.2 25.6 41.8 44.8 30.6 33.6 48.5 23.2 40.3 29.1 29.4 28.3 29.5 29.8 36.6 29.9 48.2 48.2 37.7 85.3 45.6 51.2 42.2 33.6 46.3 38.7 26.3 55.7 105.0 55.9 51.5 52.6 66.6 54.5 57.5 89.8 65.3 86.9 78.9 78.9 60.6 130.3 66.6 78.0 106.6 74.1 84.9 78.0 120.9 22.8 40.9 82.0 52.3 51.0 102.9 145.2 67.0 50.6 58.3 85.5 130.2 56.8 82.2 81.2 71.6 108.8 92.9 91.4 86.4 68.2 56.3 135.8 109.7 74.9 45.9 110.5 72.6 56.1 88.1 34.7 74.7 70.5 109.5 48.4 79.8 107.5 66.7 92.3 75.8 39.4 80.1 70.2 72.0 201.3 84.4 133.2 69.4 64.4 167.7 121.9 39.4 258.8 49.4 61.8 48.0 49.2 169.4 59.2 46.2 46.3 174.2 50.5 327.9 36.3 75.6 138.2 41.4 50.1 51.3 53.5 39.7 46.8 49.1 48.2 48.5 48.2 45.6 55.7 45.6 48.1 39.0 10.1 53.3 74.1 42.4 74.3 37.5 22.5 32.0 50.2 86.2 37.1 51.3 25.8 12.5 73.1 45.3 47.0 117.4 73.7 657.9 37.9 40.8 54.1 31.2 90.0 11.7 86.1 85.0 42.6 36.7 45.2 39.9 42.0 40.0 40.0 121.3 18.5 11.4 53.3 75.3 106.3 131.1 146.5 42.6 134.8 69.4 11.2 185.8 42.1 54.6 13.0 33.7 70.9 49.2 43.2 70.4 39.1 76.0 87.5 37.3 22.2 59.2 45.5 77.6 341.0 119.7 57.4 70.6 122.3 55.0 68.6 69.8 54.2 ATIC "AICARFT, IMPCHASE, PURH" ENSG00000138363 "5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase" P31939 2 215311956-215349773 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Purine biosynthesis" "Hydrolase, Multifunctional enzyme, Transferase" "Cancer-related genes, Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 171.4;Extravillous trophoblasts: 166.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013462, HPA021012" Supported Approved "Plasma membrane,Cytosol" NA NA 3900000 "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Cytosol "Plasma membrane" "CAB013462: , HPA021012: AB_1845169" "unprognostic (1.41e-2)" "unprognostic (2.18e-1)" "unprognostic (1.13e-2)" "unprognostic (8.46e-2)" "unprognostic (2.90e-1)" "unprognostic (3.81e-2)" "prognostic unfavorable (1.99e-7)" "unprognostic (1.86e-2)" "unprognostic (5.07e-2)" "unprognostic (1.83e-1)" "unprognostic (6.31e-3)" "unprognostic (9.21e-2)" "prognostic unfavorable (8.77e-4)" "unprognostic (1.00e-1)" "unprognostic (1.30e-1)" "unprognostic (4.18e-2)" "unprognostic (4.39e-3)" 24.8 26.0 19.8 31.7 23.4 26.4 33.9 21.4 23.5 22.2 18.8 36.4 32.0 30.0 20.3 19.4 29.4 20.4 21.3 19.6 21.5 32.7 34.6 18.0 44.9 20.5 21.5 32.0 26.2 29.6 18.6 37.3 23.3 28.7 47.5 19.1 18.8 38.4 43.2 23.8 27.2 37.0 21.0 27.6 24.5 20.1 22.9 41.8 22.5 25.4 51.8 29.1 17.6 27.5 102.2 133.8 85.1 144.0 112.5 113.2 40.6 105.4 91.9 117.4 134.9 278.6 157.3 149.6 122.8 110.0 164.5 106.7 187.8 157.0 169.5 113.4 189.3 179.1 108.7 271.5 145.4 226.1 92.0 98.4 119.8 154.7 188.5 82.0 79.7 144.5 237.0 124.4 166.3 178.7 203.4 112.1 330.3 167.4 84.9 185.8 117.3 133.4 126.4 146.5 129.3 87.8 84.3 103.1 124.3 189.2 169.7 82.9 70.2 96.0 101.2 127.3 65.8 160.3 195.7 300.1 85.6 124.5 146.8 12.6 16.4 0.4 34.6 23.5 59.1 56.6 49.0 53.8 36.3 39.9 50.0 46.9 1.8 55.4 21.1 31.7 50.2 29.0 19.8 23.4 21.4 23.5 19.6 21.5 20.5 21.5 23.3 21.0 22.9 27.5 7.2 12.8 19.3 18.6 34.7 15.0 28.2 55.0 30.7 10.0 18.2 16.1 21.1 28.6 33.3 23.9 4.2 171.4 23.3 17.6 27.4 45.2 1.1 20.7 28.2 6.1 19.2 32.2 15.4 49.3 166.3 25.3 22.4 20.8 25.3 32.9 5.3 22.2 52.4 10.1 15.4 33.8 26.4 14.4 10.8 1.7 23.9 20.2 30.2 2.8 26.1 21.3 26.8 16.6 25.7 32.4 28.5 34.3 36.3 24.0 18.8 52.7 27.3 14.7 26.3 19.2 29.0 3.3 43.8 24.6 8.5 95.4 29.8 40.7 58.4 18.1 ATOX1 HAH1 ENSG00000177556 "Antioxidant 1 copper chaperone" O00244 5 151742316-151772532 "Predicted intracellular proteins" "Copper transport, Ion transport, Transport" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 932.7;Proximal tubular cells: 1449.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055036 Approved "Nucleoplasm,Plasma membrane" NA NA 790000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Nucleoplasm "Plasma membrane" "HPA055036: " "unprognostic (5.55e-2)" "unprognostic (1.60e-1)" "unprognostic (3.84e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (3.34e-2)" "unprognostic (2.33e-1)" "unprognostic (8.60e-2)" "unprognostic (3.58e-2)" "unprognostic (2.53e-2)" "prognostic favorable (9.57e-4)" "unprognostic (2.72e-1)" "unprognostic (7.15e-2)" "unprognostic (8.18e-2)" "unprognostic (2.57e-2)" "unprognostic (1.87e-1)" "unprognostic (2.22e-1)" 102.0 136.9 173.3 65.9 183.6 73.8 100.1 180.8 201.1 84.4 181.9 84.7 81.8 73.7 98.0 112.1 64.6 63.6 107.4 170.0 189.7 217.1 260.9 80.3 142.9 181.9 184.7 57.8 57.1 180.6 81.2 69.8 183.6 100.2 64.3 24.9 93.0 74.6 53.6 102.8 83.0 75.9 184.9 124.4 76.1 72.9 185.6 82.6 119.3 39.5 128.2 91.7 84.2 192.8 112.0 181.9 104.4 73.1 275.1 224.2 136.6 197.7 225.8 197.2 267.3 248.2 235.8 224.9 233.3 345.7 437.1 102.4 129.2 502.5 161.3 143.9 220.3 98.7 118.4 255.1 254.1 137.5 108.5 291.3 105.0 246.0 161.1 144.7 295.3 138.5 83.4 642.7 305.1 276.6 102.3 304.0 59.8 249.8 382.3 61.4 120.0 350.0 190.6 98.1 136.2 80.0 169.3 476.6 763.4 117.2 234.2 165.3 328.5 201.0 159.4 246.9 345.9 522.6 513.4 136.2 271.7 92.3 846.1 154.6 207.9 199.4 75.1 247.6 69.0 98.6 67.3 66.2 171.3 68.3 53.0 58.0 155.3 97.0 177.2 217.8 103.5 117.3 173.3 183.6 180.8 201.1 170.0 189.7 181.9 184.7 183.6 184.9 185.6 192.8 209.1 57.7 56.6 8.1 93.2 67.7 79.8 204.5 70.0 22.7 250.1 246.5 112.1 165.8 102.2 211.5 14.6 146.0 65.6 213.6 541.9 207.6 178.9 121.1 171.1 183.2 150.7 104.1 6.4 159.1 218.7 127.3 96.8 135.3 73.0 117.8 236.7 932.7 671.2 25.2 9.1 171.1 164.8 221.4 166.0 321.1 83.0 230.4 238.3 4.7 436.7 185.7 88.6 5.5 22.7 318.1 238.7 103.4 170.4 124.2 727.0 1449.1 108.5 24.9 92.1 69.0 235.2 81.9 156.0 153.1 106.4 118.8 55.4 96.6 152.7 122.2 ATP10D "ATPVD, KIAA1487" ENSG00000145246 "ATPase phospholipid transporting 10D (putative)" Q9P241 4 47485275-47593486 "Enzymes, Predicted membrane proteins, Transporters" "Lipid transport, Transport" Translocase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 176.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 12 "basophil: 84.3" "Lineage enriched" "Detected in all" 12 "granulocytes: 84.3" "Cell line enhanced" "Detected in many" "HAP1: 41.6" "Low region specificity" "Detected in all" HPA050808 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Nucleoplasm, Plasma membrane" "HPA050808: AB_2681242" "unprognostic (1.62e-1)" "unprognostic (2.97e-1)" "unprognostic (4.93e-2)" "unprognostic (1.47e-2)" "unprognostic (1.16e-1)" "unprognostic (4.23e-2)" "unprognostic (1.65e-2)" "unprognostic (8.05e-2)" "unprognostic (3.48e-2)" "unprognostic (3.54e-2)" "unprognostic (3.04e-1)" "unprognostic (2.43e-1)" "prognostic favorable (5.00e-8)" "unprognostic (3.97e-2)" "unprognostic (4.47e-3)" "unprognostic (1.11e-2)" "unprognostic (3.37e-2)" 4.9 6.0 2.6 5.0 2.9 1.3 4.2 1.9 2.7 7.0 15.9 3.7 3.9 7.4 7.2 10.2 4.7 7.4 4.2 1.8 4.1 10.2 2.4 6.1 6.2 3.1 3.7 8.1 4.5 10.4 3.1 14.9 2.9 4.6 3.8 4.1 3.4 6.4 1.0 9.9 4.5 9.7 2.4 10.0 5.1 2.0 5.0 4.5 9.1 2.7 7.9 7.3 6.5 2.9 2.6 1.8 4.0 2.8 11.1 12.0 0.7 17.9 21.5 8.4 15.1 9.4 15.4 8.1 6.5 29.1 14.3 4.6 41.6 15.0 12.9 3.2 3.2 6.5 2.8 0.5 9.8 2.1 3.9 10.3 11.2 16.4 10.9 27.5 14.4 4.0 0.1 4.3 23.2 1.0 4.4 1.2 1.4 0.0 2.2 4.9 9.0 0.1 15.0 3.1 2.6 4.9 8.4 2.1 5.2 8.7 3.8 2.1 21.9 20.7 4.1 1.9 7.8 1.9 1.5 0.0 10.2 11.9 6.8 84.3 3.1 0.4 1.1 5.0 1.9 2.7 0.5 0.8 4.0 6.7 0.1 0.9 1.5 2.3 6.9 2.4 0.8 1.6 2.6 2.9 1.9 2.7 1.8 4.1 3.1 3.7 2.9 2.4 5.0 2.9 22.9 9.6 7.5 39.2 27.8 19.2 9.2 21.9 23.9 12.2 6.7 8.4 4.9 4.3 8.5 16.5 31.3 48.5 17.1 1.6 1.9 5.5 4.4 4.8 29.5 16.1 9.6 4.0 25.7 4.6 11.0 22.4 14.3 7.0 2.5 21.3 18.2 6.6 13.0 13.5 42.8 4.6 18.3 21.7 7.9 1.5 62.1 17.7 7.2 47.8 15.7 21.9 15.5 52.3 24.1 2.7 3.4 25.2 23.0 5.7 1.9 9.2 6.2 9.2 26.3 12.8 23.6 0.6 2.8 35.4 27.0 176.8 15.5 51.7 4.1 8.1 ATP13A5 FLJ16025 ENSG00000187527 "ATPase 13A5" Q4VNC0 3 193274789-193378820 "Predicted membrane proteins" Translocase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "breast: 17.3;choroid plexus: 38.5;salivary gland: 11.7" "Group enriched" "Detected in some" 5 "Astrocytes: 37.9;Oligodendrocyte precursor cells: 26.2" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.3" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 6 "neutrophil: 1.0" "Lineage enriched" "Detected in single" 9 "granulocytes: 1.0" "Cell line enhanced" "Detected in single" "SK-BR-3: 1.8" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA031771, HPA031772, HPA031774" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA031771: AB_2674038, HPA031772: , HPA031774: AB_2674039" "unprognostic (7.98e-2)" "unprognostic (3.01e-4)" "unprognostic (2.06e-3)" "unprognostic (2.72e-3)" "unprognostic (3.93e-1)" "unprognostic (1.67e-4)" "unprognostic (3.03e-1)" "unprognostic (2.31e-1)" "unprognostic (2.14e-2)" "unprognostic (1.73e-1)" "unprognostic (7.15e-2)" "unprognostic (1.10e-1)" "unprognostic (8.10e-2)" 0.0 0.1 2.3 0.0 1.9 0.2 17.3 1.5 2.7 0.0 38.5 0.0 0.0 0.1 0.8 0.7 0.1 0.0 0.2 3.1 1.8 0.2 0.0 0.5 0.1 1.6 2.3 0.2 0.1 0.2 0.3 0.0 1.5 0.0 0.0 0.8 11.7 0.0 1.3 3.9 0.0 0.0 0.8 0.0 1.6 0.4 2.4 0.0 1.3 0.1 0.2 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.1 0.2 0.0 0.0 0.1 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.1 0.0 0.0 2.3 1.9 1.5 2.7 3.1 1.8 1.6 2.3 1.5 0.8 2.4 1.8 0.1 0.0 0.5 37.9 0.0 0.0 0.0 0.3 0.0 0.0 5.8 5.8 0.7 0.0 2.2 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.5 0.1 0.0 0.1 0.0 0.0 1.1 0.2 0.0 0.4 1.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.8 0.0 0.1 0.0 1.9 0.0 0.0 0.0 26.2 1.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ATP2C2 "KIAA0703, SPCA2" ENSG00000064270 "ATPase secretory pathway Ca2+ transporting 2" O75185 16 84368527-84464187 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Calcium transport, Ion transport, Transport" Translocase "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 37.4;skin 1: 26.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 56.2;Club cells: 50.0;Intestinal goblet cells: 82.3;Oligodendrocyte precursor cells: 58.8;Respiratory ciliated cells: 78.2;Undifferentiated cells: 77.1" "Cancer enhanced" "Detected in many" "colorectal cancer: 11.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MCF7: 24.5;OE19: 44.4;RT4: 19.3;SK-BR-3: 33.0;T-47d: 11.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA052262, HPA075812" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA052262: AB_2681776, HPA075812: AB_2686765" "unprognostic (2.28e-2)" "unprognostic (6.13e-2)" "unprognostic (3.34e-2)" "prognostic favorable (6.20e-6)" "unprognostic (2.04e-1)" "unprognostic (2.41e-2)" "unprognostic (8.36e-2)" "unprognostic (1.72e-1)" "unprognostic (9.92e-2)" "unprognostic (1.89e-2)" "unprognostic (5.08e-2)" "unprognostic (2.16e-1)" "unprognostic (8.37e-3)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (4.32e-4)" "unprognostic (1.39e-1)" 0.0 0.0 1.4 2.4 1.4 11.0 2.5 0.5 1.3 6.4 0.5 30.1 27.3 1.0 0.1 4.7 6.8 4.6 0.0 1.3 1.1 1.8 0.1 10.5 0.0 1.0 0.9 0.0 0.7 3.3 1.0 0.9 1.0 12.5 37.4 0.9 19.6 0.2 0.1 26.0 20.3 0.6 0.6 0.4 5.9 0.4 1.1 0.0 8.9 0.0 0.5 4.0 4.6 0.8 6.2 0.4 0.9 0.1 0.0 0.0 6.4 0.2 0.0 0.0 0.0 5.8 5.2 0.0 0.1 0.0 0.0 9.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 2.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 24.5 0.0 0.0 0.0 44.4 0.1 0.0 0.0 0.2 0.0 19.3 4.9 0.0 0.0 33.0 0.2 0.9 11.1 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 1.4 1.4 0.5 1.3 1.3 1.1 1.0 0.9 1.0 0.6 1.1 0.8 0.0 32.1 56.2 4.2 0.0 0.6 14.3 39.9 0.6 1.3 20.8 3.2 0.8 5.7 50.0 0.0 0.0 2.0 0.1 44.4 0.0 9.0 3.2 26.8 2.5 0.7 34.2 0.0 8.3 2.5 2.4 0.5 22.4 28.0 8.9 0.0 0.0 0.1 0.3 0.0 1.8 82.3 8.2 0.0 1.2 1.9 0.0 0.6 1.8 1.0 0.0 1.9 0.0 58.8 2.4 4.7 29.2 0.0 0.0 13.8 10.2 1.8 78.2 5.2 0.0 0.1 1.8 0.8 1.0 1.5 1.1 24.1 0.9 0.2 77.1 9.9 ATP8A2 "ATPIB, ML-1" ENSG00000132932 "ATPase phospholipid transporting 8A2" Q9NTI2 13 25371974-26025851 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Lipid transport, Transport" Translocase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 21.6;pituitary gland: 15.2;retina: 17.2" "Group enriched" "Detected in many" 6 "Excitatory neurons: 518.7;Inhibitory neurons: 727.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 19.9;JURKAT: 9.8;MOLT-4: 3.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039926, HPA040033" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA039926: AB_10794205, HPA040033: AB_2676809" "unprognostic (3.79e-2)" "unprognostic (4.28e-2)" "unprognostic (3.32e-2)" "unprognostic (1.95e-4)" "unprognostic (3.57e-2)" "unprognostic (1.89e-1)" "unprognostic (1.31e-2)" "unprognostic (2.97e-3)" "unprognostic (2.77e-1)" "unprognostic (3.66e-1)" "unprognostic (4.96e-4)" "unprognostic (1.24e-1)" "unprognostic (1.18e-2)" "unprognostic (4.20e-5)" "unprognostic (9.10e-2)" "unprognostic (2.95e-1)" "unprognostic (7.22e-2)" 0.1 2.1 5.5 0.3 6.7 0.0 0.6 8.0 21.6 0.2 0.0 0.4 0.3 0.6 1.8 0.0 0.0 0.1 0.1 8.7 19.3 0.3 0.0 0.8 0.6 12.8 4.6 0.2 0.6 0.0 15.2 0.2 12.1 0.1 0.2 17.2 0.1 0.0 0.3 0.1 0.3 0.1 0.2 0.3 0.6 2.9 6.6 1.0 0.1 0.1 0.2 0.2 0.0 6.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.0 0.2 1.5 0.0 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 19.9 0.1 0.0 0.0 0.0 0.6 0.5 9.8 0.0 0.0 1.7 0.1 3.9 0.0 2.0 0.0 0.7 0.0 2.7 0.9 0.2 0.0 3.2 0.0 0.2 0.2 0.1 0.2 0.0 0.4 0.2 0.0 1.0 0.3 0.4 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.0 0.2 0.1 5.5 6.7 8.0 21.6 8.7 19.3 12.8 4.6 12.1 0.2 6.6 6.8 0.7 0.0 12.2 9.4 0.8 1.0 0.2 0.3 0.0 21.5 1.5 0.3 2.5 1.5 0.4 0.0 95.9 1.5 0.4 0.0 0.0 0.3 39.0 1.2 23.6 2.6 0.0 0.8 518.7 0.0 0.4 1.7 1.1 0.9 5.1 3.7 0.0 0.0 3.2 21.9 727.7 0.0 0.0 0.0 0.7 30.3 0.9 0.3 0.0 9.4 0.0 7.2 1.0 88.4 24.7 0.0 0.0 1.2 0.1 0.2 0.0 1.3 0.3 91.6 13.1 0.3 0.8 19.8 12.5 0.0 0.4 1.1 1.8 10.1 0.1 0.1 ATXN10 "E46L, FLJ37990, SCA10" ENSG00000130638 "Ataxin 10" Q9UBB4 22 45671798-45845307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049531 Approved Supported "Plasma membrane,Cytosol" NA NA 40000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 8: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "HPA049531: AB_2680806" "unprognostic (5.73e-2)" "unprognostic (1.97e-1)" "unprognostic (1.27e-2)" "unprognostic (5.76e-2)" "unprognostic (3.01e-2)" "unprognostic (7.50e-2)" "unprognostic (1.19e-3)" "unprognostic (3.18e-1)" "unprognostic (2.15e-2)" "unprognostic (5.07e-2)" "unprognostic (8.38e-2)" "unprognostic (3.51e-1)" "unprognostic (1.23e-2)" "unprognostic (1.18e-1)" "unprognostic (6.22e-2)" "unprognostic (7.48e-2)" "unprognostic (6.98e-2)" 40.9 59.5 42.2 34.7 46.1 41.9 41.7 35.3 56.8 50.6 26.9 43.7 23.8 50.0 39.0 46.4 56.1 39.6 74.5 50.2 49.6 53.5 64.8 38.2 48.3 37.6 40.1 57.7 57.4 64.9 56.1 48.8 42.1 46.5 36.3 55.1 41.6 40.9 70.6 34.9 27.8 50.2 42.5 34.2 34.4 57.3 46.5 65.9 63.0 59.3 51.6 51.1 45.8 44.5 163.4 84.9 156.2 95.0 70.5 107.6 85.4 181.0 194.3 128.1 139.4 42.9 106.4 169.3 73.2 184.5 66.4 94.4 114.3 121.3 137.7 32.8 119.4 78.9 141.7 79.8 101.9 213.1 56.4 109.0 82.9 66.5 103.1 153.1 96.3 76.2 58.7 89.8 197.2 69.6 116.7 95.6 104.2 90.8 64.0 166.2 60.7 135.9 162.6 152.3 86.9 136.6 113.5 67.2 129.2 119.8 101.4 111.9 87.6 127.5 47.7 46.0 61.4 87.8 57.3 136.8 79.5 88.5 138.5 80.5 99.9 91.8 69.0 121.7 92.3 72.1 68.0 84.3 163.9 72.6 74.4 71.9 4.7 86.2 138.5 58.1 70.8 120.2 42.2 46.1 35.3 56.8 50.2 49.6 37.6 40.1 42.1 42.5 46.5 44.5 38.1 35.3 33.3 127.3 50.6 50.5 124.2 156.0 68.9 66.3 45.4 50.0 94.2 65.8 76.7 58.8 20.9 101.9 32.3 17.1 68.4 91.1 69.2 53.7 53.7 44.4 60.3 63.1 148.6 69.5 106.3 70.7 34.1 49.8 39.9 93.5 36.4 54.9 72.2 70.7 157.9 35.4 79.3 49.0 36.5 40.6 57.5 48.3 24.9 103.0 67.9 79.3 27.8 186.5 168.1 51.6 24.0 75.6 53.3 115.2 18.6 66.9 67.6 53.6 46.0 45.1 54.6 133.8 108.3 65.1 41.5 52.3 47.8 102.2 44.5 102.0 ATXN7L3 DKFZp761G2113 ENSG00000087152 "Ataxin 7 like 3" Q14CW9 17 44191805-44200113 "Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064316 Supported Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 20: HeLa - Mitochondria" "Cluster 10: Non-specific - Unknown function" "Nuclear speckles" "Plasma membrane" "HPA064316: AB_2685243" "unprognostic (2.37e-2)" "unprognostic (8.87e-3)" "unprognostic (1.10e-1)" "unprognostic (3.74e-2)" "unprognostic (3.75e-2)" "unprognostic (1.23e-1)" "prognostic unfavorable (4.03e-4)" "unprognostic (2.86e-3)" "unprognostic (6.74e-3)" "unprognostic (1.09e-1)" "unprognostic (1.50e-1)" "unprognostic (1.00e-1)" "prognostic unfavorable (2.87e-4)" "unprognostic (1.21e-3)" "unprognostic (9.05e-2)" "unprognostic (3.75e-2)" "unprognostic (1.40e-1)" 23.3 24.6 51.0 32.6 58.1 45.0 21.3 28.0 76.6 28.4 12.0 26.8 31.2 28.3 25.9 40.1 26.5 24.1 24.9 58.5 35.9 29.2 28.0 25.2 37.2 58.3 42.4 25.5 24.2 24.5 35.1 30.7 60.6 26.9 24.3 21.5 27.9 27.7 25.3 31.2 29.6 25.8 33.0 36.3 28.3 36.9 48.3 42.1 29.1 22.6 35.5 28.7 28.1 54.1 40.9 67.7 73.3 47.8 50.1 49.5 39.8 49.1 54.3 61.4 57.7 52.0 45.1 71.3 38.6 55.5 56.6 43.9 57.7 46.1 51.2 83.6 57.2 48.5 58.9 58.5 49.3 76.3 94.3 56.1 69.0 51.7 54.1 65.0 60.3 54.2 66.1 43.5 40.8 30.7 92.3 58.0 55.1 36.7 52.5 62.8 70.9 54.1 49.8 57.9 46.5 59.0 29.0 25.4 50.5 101.4 62.0 67.1 52.2 61.5 63.8 32.3 46.5 52.1 73.8 86.4 40.6 32.6 36.8 0.4 1.2 1.5 1.7 0.7 1.0 1.4 1.4 1.1 1.0 2.4 1.0 1.3 2.5 0.5 0.9 1.6 0.8 1.1 51.0 58.1 28.0 76.6 58.5 35.9 58.3 42.4 60.6 33.0 48.3 54.1 14.3 3.2 3.7 5.5 9.4 7.1 5.6 8.0 8.6 17.4 13.7 9.1 6.2 5.7 6.6 18.4 16.7 6.3 11.3 22.2 3.9 7.1 14.7 14.0 16.9 10.5 14.4 4.0 9.1 13.1 6.7 7.2 8.6 20.7 2.5 9.9 10.4 8.1 8.4 28.6 8.6 11.0 4.1 11.1 10.9 40.0 9.0 10.0 5.4 8.4 12.7 8.6 5.2 3.0 5.3 15.0 13.6 5.7 5.5 8.6 14.1 4.6 7.6 13.9 6.6 6.7 9.3 6.3 8.5 11.0 10.5 13.7 10.0 10.4 11.2 9.1 AVPI1 "PP5395, VIP32, VIT32" ENSG00000119986 "Arginine vasopressin induced 1" Q5T686 10 97677424-97687241 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skin 1: 100.7" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 246.7;Granulosa cells: 385.5;Langerhans cells: 326.1;Late spermatids: 278.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HeLa: 119.7;HHSteC: 119.1;hTCEpi: 230.5;SK-MEL-30: 194.5;U-2197: 134.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037649 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA037649: AB_10671879" "unprognostic (4.57e-2)" "unprognostic (3.28e-2)" "unprognostic (3.04e-2)" "unprognostic (4.79e-2)" "unprognostic (2.73e-1)" "unprognostic (1.25e-1)" "unprognostic (4.37e-3)" "unprognostic (4.60e-2)" "unprognostic (7.34e-3)" "unprognostic (8.56e-3)" "unprognostic (2.29e-3)" "unprognostic (1.23e-1)" "unprognostic (3.91e-3)" "unprognostic (4.04e-1)" "unprognostic (2.03e-1)" "unprognostic (8.66e-2)" "unprognostic (3.83e-3)" 32.1 41.5 18.5 6.5 25.4 5.0 21.2 21.9 23.2 38.1 16.2 24.6 14.0 11.2 4.7 26.2 18.9 10.4 22.4 18.3 19.8 12.1 46.9 22.5 2.4 23.7 20.2 85.6 9.4 5.6 19.2 16.9 21.9 26.3 18.9 25.5 22.7 16.6 12.5 100.7 15.6 5.3 22.4 20.8 30.5 16.0 20.8 2.0 9.1 3.9 4.4 25.5 46.0 29.5 38.8 99.8 0.5 14.3 20.2 9.1 20.0 18.5 100.7 25.0 37.5 18.8 47.2 0.8 13.0 10.5 18.0 40.0 7.6 32.3 9.4 1.0 8.9 2.6 119.7 52.6 119.1 2.6 3.0 14.6 230.5 18.7 49.1 22.8 3.4 3.6 5.7 2.0 14.0 33.4 1.7 3.1 3.5 10.6 9.3 1.3 11.3 1.5 24.9 20.9 1.7 4.0 63.9 22.7 194.5 3.2 17.2 3.1 5.5 5.9 11.7 134.4 4.6 4.4 3.3 0.8 22.2 8.1 3.8 0.0 6.2 2.3 4.2 5.7 2.0 2.8 2.8 3.1 11.1 2.0 3.0 3.7 0.5 2.0 0.5 2.3 2.6 2.9 18.5 25.4 21.9 23.2 18.3 19.8 23.7 20.2 21.9 22.4 20.8 29.5 6.3 19.2 19.0 0.7 8.0 96.0 87.6 246.7 145.1 9.6 13.6 16.8 9.7 52.9 63.4 38.6 6.2 149.6 15.4 137.5 43.0 18.8 60.9 33.2 17.1 11.4 31.8 2.1 3.6 24.1 64.8 23.4 58.1 57.9 6.3 385.5 34.2 42.4 41.8 13.5 4.3 70.4 48.8 21.7 326.1 278.5 10.2 49.6 83.6 0.0 6.4 128.2 2.1 0.5 4.4 43.3 100.6 14.7 5.9 55.2 109.0 11.2 16.7 14.6 6.6 10.2 19.3 3.5 4.9 68.0 108.4 194.7 19.0 10.9 100.6 106.3 BAIAP2 "BAP2, IRSp53, WAML" ENSG00000175866 "BAR/IMD domain containing adaptor protein 2" Q9UQB8 17 81035122-81117432 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Urothelial cells: 185.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 19.5" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023310, HPA027421" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 18000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA023310: AB_1845264, HPA027421: AB_10602392" "unprognostic (2.20e-1)" "unprognostic (1.84e-3)" "unprognostic (5.81e-2)" "unprognostic (2.28e-2)" "unprognostic (1.73e-1)" "unprognostic (6.97e-3)" "unprognostic (3.73e-3)" "unprognostic (1.53e-1)" "unprognostic (6.77e-2)" "unprognostic (1.45e-2)" "unprognostic (4.23e-2)" "unprognostic (2.94e-1)" "unprognostic (7.04e-2)" "unprognostic (6.77e-2)" "unprognostic (7.15e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (7.58e-6)" 23.9 18.2 129.1 7.4 140.0 2.6 27.1 95.7 176.1 49.9 104.6 44.0 6.7 30.9 46.5 132.9 37.6 29.3 24.2 163.7 103.1 38.0 85.7 49.1 6.9 68.0 81.0 13.7 13.4 19.9 56.3 31.8 68.3 61.3 12.1 16.2 57.5 27.6 13.1 132.4 14.7 19.3 70.5 11.8 62.3 26.3 119.9 11.8 27.1 9.8 25.3 23.3 73.2 121.9 99.9 45.1 28.1 36.6 22.2 29.0 32.8 40.2 26.1 35.7 15.8 60.9 49.1 0.5 28.3 35.8 73.5 93.6 26.1 46.1 13.7 0.4 32.8 20.2 41.3 46.4 20.7 0.0 28.2 12.5 53.0 29.5 15.4 32.7 19.5 1.1 26.4 0.6 20.6 51.2 4.0 22.3 11.8 65.6 38.1 6.0 6.6 81.3 108.5 34.5 36.8 39.9 64.2 91.3 110.1 23.1 80.4 22.6 23.8 81.6 78.4 13.8 43.4 1.4 0.3 1.4 72.0 3.3 18.3 0.0 7.9 0.5 3.2 9.4 1.0 0.1 1.2 1.0 10.3 0.1 1.3 1.8 5.4 1.9 9.2 19.5 0.5 3.2 129.1 140.0 95.7 176.1 163.7 103.1 68.0 81.0 68.3 70.5 119.9 121.9 74.1 76.9 39.0 13.4 6.2 63.7 138.4 42.3 94.4 37.1 49.4 37.1 22.5 25.8 47.2 22.0 79.2 77.1 16.6 18.8 7.9 9.8 10.5 80.8 10.4 35.7 49.3 0.8 65.3 5.1 9.2 28.0 88.2 79.7 13.4 3.1 45.0 78.6 43.2 11.8 13.6 29.1 24.4 18.3 58.2 29.4 6.8 31.2 40.9 13.1 18.6 18.5 0.0 4.5 5.9 14.8 8.0 3.8 3.1 77.0 3.7 25.4 110.8 19.1 0.0 10.4 13.3 7.6 33.0 103.6 75.3 101.0 13.9 8.2 14.7 185.1 BAIAP2L1 IRTKS ENSG00000006453 "BAR/IMD domain containing adaptor protein 2 like 1" Q9UHR4 7 98291650-98401090 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "stomach 1: 58.8" "Cell type enhanced" "Detected in many" "Gastric mucus-secreting cells: 108.1;Prostatic glandular cells: 114.7;Urothelial cells: 147.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "SK-BR-3: 72.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" "HPA019484, HPA021257, HPA023874, HPA029503" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "HPA019484: AB_1845265, HPA021257: AB_1845266, HPA023874: AB_1845267, HPA029503: AB_10602330" "unprognostic (1.75e-1)" "unprognostic (1.86e-3)" "unprognostic (1.21e-1)" "unprognostic (1.22e-1)" "unprognostic (3.39e-2)" "unprognostic (1.71e-1)" "unprognostic (1.42e-2)" "unprognostic (1.00e-1)" "unprognostic (2.95e-1)" "unprognostic (2.80e-2)" "unprognostic (8.31e-3)" "unprognostic (4.56e-2)" "unprognostic (1.34e-2)" "unprognostic (9.09e-2)" "unprognostic (2.79e-1)" "unprognostic (1.46e-1)" "unprognostic (1.44e-1)" 5.8 20.7 1.5 6.2 1.5 0.4 7.8 1.3 1.7 10.1 3.1 23.0 28.6 2.8 1.4 29.2 11.6 15.5 5.2 1.4 2.1 13.9 33.4 14.0 1.4 1.7 1.7 1.3 31.2 13.1 13.0 10.2 1.8 26.2 21.4 0.6 23.6 2.6 2.8 19.9 25.4 2.6 1.5 1.9 58.8 9.8 1.8 2.1 14.9 1.6 4.6 16.8 17.1 1.8 43.2 33.6 0.9 0.7 0.0 1.5 55.0 10.9 7.1 5.6 4.1 47.0 62.9 1.8 15.9 4.1 47.4 37.3 15.6 46.1 5.0 0.2 20.3 0.0 14.3 27.0 6.7 0.0 14.7 1.5 61.0 3.2 44.4 12.3 0.2 0.1 26.4 0.1 4.8 36.1 0.1 0.1 26.3 61.8 18.5 0.1 0.5 7.0 35.2 37.2 23.5 4.6 25.3 72.2 12.8 35.3 20.2 1.0 1.4 8.3 39.6 1.6 5.1 0.9 13.1 21.8 0.9 5.4 13.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 1.5 1.5 1.3 1.7 1.4 2.1 1.7 1.7 1.8 1.5 1.8 1.8 16.9 12.8 22.9 23.5 0.8 16.7 64.8 31.5 14.2 0.6 17.4 7.6 2.3 30.0 36.3 22.0 4.2 11.8 5.5 100.3 9.8 60.8 33.1 25.2 3.0 11.2 32.2 2.7 23.1 77.6 78.4 2.2 108.1 33.4 0.0 4.5 0.7 16.6 2.4 1.7 26.1 53.6 18.3 0.3 1.7 52.5 0.9 1.0 8.8 37.5 2.6 1.2 0.0 26.7 31.4 102.6 84.7 0.7 0.6 114.7 35.3 2.4 58.6 0.8 0.0 1.9 6.7 50.0 56.3 22.4 19.5 12.2 1.9 0.2 44.7 147.8 BCAR1 "CAS, CASS1, Crkas, P130Cas" ENSG00000050820 "BCAR1 scaffold protein, Cas family member" P56945 16 75228181-75268053 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Diabetes mellitus" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000443, HPA042282" Approved Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 72: Non-specific - Transcription" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB000443: , HPA042282: AB_2677929" "unprognostic (5.44e-2)" "unprognostic (2.96e-1)" "unprognostic (1.61e-2)" "unprognostic (1.67e-2)" "unprognostic (2.17e-1)" "unprognostic (5.43e-3)" "prognostic unfavorable (9.11e-5)" "prognostic unfavorable (1.24e-4)" "unprognostic (2.15e-1)" "unprognostic (3.49e-2)" "unprognostic (5.18e-2)" "unprognostic (1.77e-2)" "prognostic favorable (4.55e-8)" "unprognostic (3.38e-1)" "unprognostic (3.60e-2)" "unprognostic (8.20e-2)" "unprognostic (2.20e-1)" 34.7 22.3 3.5 4.2 5.8 0.0 27.9 16.9 6.6 37.7 6.3 34.4 15.8 39.2 2.6 22.5 25.3 9.4 47.1 2.3 7.9 47.3 34.2 38.8 2.1 3.9 1.9 19.7 32.4 5.9 29.5 14.1 2.3 25.6 3.5 1.3 25.5 5.7 93.8 18.2 33.1 3.8 0.0 33.7 44.6 34.3 4.2 0.9 26.8 6.8 1.1 24.9 26.2 15.8 21.8 36.8 17.5 6.0 6.7 6.3 34.1 29.5 17.1 20.9 16.4 46.5 32.1 1.9 38.2 33.3 23.6 18.2 6.1 34.0 6.0 0.1 20.0 0.0 23.7 37.2 16.7 0.1 15.1 19.1 16.3 25.3 12.5 12.3 57.9 0.0 20.0 1.0 12.6 48.9 0.1 1.3 23.4 16.1 24.0 0.8 7.9 8.2 19.1 27.9 21.4 31.5 28.7 6.6 11.2 8.4 15.0 5.4 53.6 34.4 29.5 8.8 44.2 8.0 4.7 0.7 22.2 0.1 24.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 5.8 16.9 6.6 2.3 7.9 3.9 1.9 2.3 0.0 4.2 15.8 30.1 22.4 6.9 9.4 1.2 28.0 59.7 36.8 12.0 26.5 20.3 14.4 22.9 31.5 21.8 22.0 6.2 46.8 0.7 75.7 27.4 51.9 19.0 13.7 27.9 49.2 34.8 0.0 13.1 61.8 25.7 21.1 71.9 22.5 8.9 15.0 46.8 21.0 6.0 13.5 11.7 42.1 12.2 1.4 6.3 26.8 16.4 2.1 32.0 10.3 0.6 12.9 0.0 19.1 31.2 68.5 59.6 33.4 1.4 58.4 57.4 38.9 13.1 6.8 19.7 8.5 38.5 20.6 17.1 12.5 17.6 36.1 2.2 10.9 33.7 62.7 BCL2L12 ENSG00000126453 "BCL2 like 12" Q9HB09 19 49665142-49673916 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 126.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020856 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Vesicles "Plasma membrane" "HPA020856: AB_1845320" "unprognostic (2.59e-1)" "unprognostic (3.96e-2)" "unprognostic (2.24e-1)" "unprognostic (5.72e-2)" "unprognostic (3.64e-1)" "unprognostic (3.68e-2)" "unprognostic (6.80e-3)" "unprognostic (3.87e-3)" "unprognostic (6.12e-2)" "unprognostic (8.90e-2)" "unprognostic (1.60e-2)" "unprognostic (2.33e-2)" "prognostic unfavorable (8.75e-5)" "unprognostic (8.67e-2)" "unprognostic (3.62e-2)" "unprognostic (2.37e-1)" "unprognostic (2.56e-1)" 8.5 8.5 3.8 14.7 3.9 18.2 9.5 3.9 5.1 8.3 5.0 11.9 10.5 9.9 3.2 13.4 9.5 6.5 9.4 3.6 3.8 7.8 16.6 9.6 20.6 4.4 4.2 9.7 15.5 4.5 2.7 10.3 4.1 11.3 7.3 1.7 11.7 5.0 14.0 8.5 11.9 6.8 4.1 16.7 11.7 10.1 4.1 17.3 7.6 13.5 15.8 9.6 8.7 4.3 105.2 63.7 49.8 94.8 12.6 12.6 56.9 58.2 23.3 57.2 60.6 89.2 55.4 58.4 26.7 20.2 32.4 49.7 46.3 39.4 30.7 74.1 97.4 53.1 43.5 62.0 11.4 56.6 62.2 15.5 19.0 64.3 18.2 11.5 38.7 79.2 138.8 73.3 30.8 59.1 67.6 91.8 62.4 61.8 77.4 86.6 54.3 62.7 24.8 52.0 0.9 29.4 59.5 79.0 41.8 35.6 33.0 70.3 22.8 64.1 75.2 45.5 96.4 61.2 102.4 114.3 27.2 78.0 64.3 11.0 7.4 17.0 12.5 12.2 14.6 14.8 13.2 12.3 6.5 14.6 12.8 13.1 10.9 15.8 8.6 25.9 14.4 6.3 3.8 3.9 3.9 5.1 3.6 3.8 4.4 4.2 4.1 4.1 4.1 4.3 10.2 9.6 13.1 3.3 22.1 32.2 37.4 23.3 14.2 1.0 35.2 34.2 5.0 10.0 16.5 5.5 0.0 70.3 18.2 14.6 7.9 25.7 8.3 17.0 11.5 13.2 6.7 18.5 0.2 25.8 126.3 16.2 9.2 20.1 9.5 18.9 11.0 13.1 37.6 0.0 0.2 15.7 18.3 12.6 16.1 6.4 6.5 15.5 26.6 1.0 22.1 3.5 24.7 0.0 1.6 34.5 16.6 6.0 44.3 20.5 6.5 10.4 12.6 1.2 13.1 14.0 15.1 11.6 22.3 19.7 19.5 55.7 15.7 11.7 23.3 27.7 BCORL1 "CXorf10, FLJ11362" ENSG00000085185 "BCL6 corepressor like 1" Q5H9F3 X 129981107-130058071 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Repressor" "Autism spectrum disorder, Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Syncytiotrophoblasts: 93.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.6;HAP1: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031775, HPA031777, HPA068568" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 23: Testis - Cell cycle regulation" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Nucleoplasm "Plasma membrane" "HPA031775: AB_10602332, HPA031777: AB_10671578, HPA068568: AB_2686007" "unprognostic (8.07e-2)" "unprognostic (2.78e-2)" "unprognostic (7.09e-2)" "prognostic unfavorable (2.20e-5)" "unprognostic (4.58e-1)" "unprognostic (1.68e-3)" "unprognostic (1.96e-3)" "unprognostic (5.56e-3)" "unprognostic (2.39e-1)" "unprognostic (8.02e-2)" "unprognostic (4.46e-2)" "unprognostic (2.04e-1)" "prognostic unfavorable (5.00e-4)" "unprognostic (9.18e-2)" "unprognostic (2.60e-2)" "unprognostic (3.09e-1)" "unprognostic (1.41e-2)" 3.5 3.1 2.4 2.6 2.5 5.6 2.1 4.5 2.6 3.5 0.4 2.9 2.6 4.5 2.2 2.6 4.3 2.0 2.8 2.4 2.7 2.6 2.0 2.9 1.7 2.9 2.1 5.5 4.5 5.8 2.6 11.3 1.9 3.2 2.0 2.0 3.3 3.7 3.3 2.9 2.8 4.3 1.4 2.8 2.2 6.5 2.1 2.3 4.5 3.3 1.7 2.6 2.6 1.9 3.4 8.0 18.7 29.6 10.6 8.0 5.3 4.5 5.2 5.7 6.5 9.6 2.2 1.5 9.9 8.8 5.5 2.0 44.2 1.8 5.2 3.4 6.7 16.2 3.9 3.1 5.2 3.8 4.8 4.9 3.6 11.0 0.6 8.3 6.8 5.2 7.7 16.4 3.6 1.9 6.0 11.3 5.2 2.6 5.9 12.6 7.5 2.2 3.0 0.4 3.2 10.9 2.3 0.7 3.0 9.4 6.7 5.9 5.9 4.5 6.0 5.7 4.5 5.1 10.1 2.5 2.9 7.8 2.2 0.0 0.3 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.1 0.7 0.2 0.1 0.1 0.0 0.2 2.4 2.5 4.5 2.6 2.4 2.7 2.9 2.1 1.9 1.4 2.1 1.9 5.4 0.0 2.8 6.8 2.9 11.9 2.8 2.2 10.8 1.7 12.5 7.5 7.1 4.3 1.9 7.3 0.0 14.1 6.1 3.7 0.0 3.0 0.5 3.7 7.0 7.9 12.0 2.5 4.6 1.1 4.8 6.9 2.6 4.7 7.0 4.3 4.6 2.8 3.2 8.4 4.4 2.4 2.0 2.2 5.9 1.2 4.7 2.7 7.2 5.6 3.0 2.3 4.1 4.5 8.5 2.6 1.9 3.8 3.2 3.8 4.2 2.3 2.9 1.3 6.6 8.0 6.1 3.4 6.9 9.2 11.5 93.4 4.9 0.9 3.6 2.8 BEND6 "bA203B9.1, C6orf65, FLJ30162" ENSG00000151917 "BEN domain containing 6" Q5SZJ8 6 56955107-57027346 "Predicted intracellular proteins" "Neurogenesis, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 30.9;retina: 11.8" "Cell type enhanced" "Detected in many" "Bipolar cells: 82.6;Excitatory neurons: 87.3;Horizontal cells: 42.1;Inhibitory neurons: 118.6;Oligodendrocyte precursor cells: 49.8" "Cancer enriched" "Detected in many" 6 "glioma: 4.1" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 5 "plasmacytoid DC: 8.8" "Lineage enriched" "Detected in many" 6 "dendritic cells: 8.8" "Cell line enhanced" "Detected in many" "ASC TERT1: 28.8;fHDF/TERT166: 28.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031605, HPA052973" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA031605: AB_10602395, HPA052973: AB_2682002" "unprognostic (4.27e-1)" "unprognostic (7.05e-2)" "unprognostic (4.42e-2)" "unprognostic (1.18e-6)" "unprognostic (2.44e-1)" "unprognostic (2.10e-1)" "unprognostic (1.17e-1)" "unprognostic (1.77e-2)" "unprognostic (9.41e-3)" "unprognostic (1.57e-1)" "unprognostic (8.82e-2)" "unprognostic (1.94e-2)" "unprognostic (9.84e-6)" "unprognostic (9.27e-3)" "unprognostic (1.51e-1)" "unprognostic (4.79e-2)" "unprognostic (2.98e-3)" 1.2 2.1 12.1 1.5 14.2 0.7 0.6 30.5 30.9 4.0 2.9 1.4 0.5 2.8 0.7 1.2 1.0 3.8 2.4 12.6 16.0 0.6 0.2 0.6 0.9 19.5 16.0 2.0 0.4 0.7 1.7 2.0 20.4 2.4 1.5 11.8 0.5 2.4 3.9 1.0 0.7 3.6 12.1 0.8 0.8 1.0 15.7 1.1 0.8 0.6 0.8 2.8 1.7 21.7 5.4 2.2 1.3 0.6 17.6 28.8 4.9 16.1 15.6 7.1 8.2 0.2 2.4 0.1 5.2 28.7 9.9 0.7 1.8 0.8 8.7 2.4 1.0 3.6 7.5 0.4 4.7 10.3 0.2 12.7 4.5 9.8 4.3 11.9 4.7 13.3 4.6 9.2 14.3 5.5 6.2 2.5 4.4 0.3 1.3 0.1 0.2 2.6 2.6 5.4 6.1 6.2 10.8 1.3 1.4 6.1 0.3 5.9 6.1 21.5 0.7 14.5 3.6 12.6 15.2 4.3 12.6 6.5 19.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 1.5 0.0 8.8 0.0 0.1 12.1 14.2 30.5 30.9 12.6 16.0 19.5 16.0 20.4 12.1 15.7 21.7 0.4 0.0 0.0 16.6 0.3 0.9 0.2 0.2 0.0 82.6 0.2 1.1 3.6 0.0 0.7 0.0 4.2 0.5 10.8 0.0 0.0 0.2 0.6 0.5 11.9 0.2 0.0 0.0 87.3 0.4 1.6 5.6 0.0 0.5 0.0 13.5 1.1 0.0 0.1 42.1 118.6 0.0 0.0 0.0 4.0 0.8 1.8 1.1 3.6 13.1 0.3 4.9 0.0 49.8 22.9 0.6 0.0 3.0 0.0 0.4 0.0 1.0 0.0 4.8 0.0 8.7 2.7 0.7 5.8 0.2 1.0 0.0 0.1 4.4 0.0 0.1 BFSP1 "CP115, CP94, filensin, LIFL-H" ENSG00000125864 "Beaded filament structural protein 1" Q12934 20 17493905-17569220 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Eye lens protein" Cataract "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Late spermatids: 5.7;NK-cells: 17.5;Spermatogonia: 11.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "gdT-cell: 2.5" "Lineage enhanced" "Detected in single" "T-cells: 2.5" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 10.8;RPTEC TERT1: 19.5;SK-BR-3: 10.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "amygdala: 2.5;cerebral cortex: 3.2;hippocampal formation: 3.6" "HPA040748, HPA042038" Enhanced Supported "Plasma membrane,Cytosol" No No "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 43: Testis - Unknown function" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040748: AB_10963786, HPA042038: AB_10964054" "unprognostic (2.24e-3)" "unprognostic (1.99e-1)" "unprognostic (1.63e-1)" "prognostic favorable (1.39e-4)" "unprognostic (1.07e-2)" "unprognostic (2.21e-1)" "unprognostic (1.22e-6)" "unprognostic (5.11e-2)" "unprognostic (5.53e-1)" "unprognostic (2.10e-4)" "unprognostic (1.75e-1)" "unprognostic (8.81e-2)" "unprognostic (3.35e-4)" "unprognostic (4.45e-2)" "unprognostic (2.73e-2)" "unprognostic (1.78e-2)" "unprognostic (7.50e-2)" 1.1 1.3 2.0 0.5 2.2 0.4 1.1 1.6 2.1 1.3 2.0 1.3 0.3 1.8 1.4 1.1 1.3 1.3 0.7 2.2 2.1 3.7 0.3 1.7 0.3 1.7 1.8 1.5 1.9 1.0 0.9 1.9 1.8 1.2 0.5 0.4 1.5 1.1 0.3 1.0 0.7 1.1 1.5 0.4 0.9 3.8 2.1 0.2 2.5 0.4 0.3 1.3 0.9 2.4 0.8 8.1 2.6 0.3 0.7 2.6 0.4 2.0 9.5 1.3 1.2 3.7 7.0 0.0 1.6 1.2 5.1 1.2 2.8 1.6 1.0 1.8 2.1 0.6 1.2 1.1 1.5 0.5 0.9 3.1 4.9 0.7 2.3 10.8 5.7 0.5 0.3 0.4 4.2 1.6 0.0 1.2 6.1 5.2 2.2 0.0 1.8 0.4 19.5 1.5 2.7 0.3 2.4 10.6 4.3 1.2 5.2 1.8 6.5 0.3 0.6 0.7 2.0 0.0 0.1 0.0 1.4 0.0 1.6 0.0 0.0 0.0 2.5 0.0 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.2 0.3 0.7 0.0 0.0 0.0 0.2 2.0 2.2 1.6 2.1 2.2 2.1 1.7 1.8 1.8 1.5 2.1 2.4 3.8 3.2 1.7 0.7 0.0 0.9 0.5 0.7 0.0 0.2 1.9 1.5 1.2 1.5 0.4 0.0 0.0 1.2 2.6 0.1 1.9 0.8 1.3 1.1 0.4 3.1 0.0 0.8 2.1 0.9 1.7 1.2 1.5 0.6 0.0 0.2 3.9 0.2 0.5 0.0 1.2 0.2 0.0 0.0 0.8 5.7 1.8 0.2 1.8 2.8 0.0 1.0 17.5 0.5 1.1 0.8 0.0 0.0 0.4 0.4 0.0 0.3 1.8 0.1 0.0 0.5 1.0 1.1 11.9 1.1 0.9 0.4 1.0 0.4 0.3 0.5 BFSP2 "CP47, CP49, LIFL-L, phakinin" ENSG00000170819 "Beaded filament structural protein 2" Q13515 3 133400056-133475222 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Sensory transduction, Vision" "Eye lens protein" "Cataract, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "B-cells: 6.3;Melanocytes: 5.4;Plasma cells: 10.6" "Cancer enriched" "Detected in single" 7 "testis cancer: 1.7" "Not detected" "Not detected" "Immune cell enriched" "Detected in some" 8 "T-reg: 13.4" "Lineage enriched" "Detected in single" 43 "T-cells: 13.4" "Group enriched" "Detected in some" 6 "Daudi: 2.4;U-698: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA038464, HPA062959" Enhanced Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA038464: AB_10672746, HPA062959: AB_2684912" "unprognostic (1.58e-3)" "unprognostic (7.47e-4)" "unprognostic (1.04e-2)" "unprognostic (2.32e-1)" "unprognostic (9.59e-2)" "unprognostic (4.04e-5)" "unprognostic (8.13e-2)" "unprognostic (5.57e-2)" "unprognostic (6.71e-2)" "unprognostic (1.91e-3)" "unprognostic (1.74e-2)" "unprognostic (4.70e-2)" "unprognostic (1.68e-5)" "unprognostic (2.11e-2)" "unprognostic (1.63e-1)" "unprognostic (8.23e-2)" "unprognostic (2.21e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 2.6 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.6 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 13.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 1.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.0 0.0 1.8 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.0 0.0 0.4 0.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.9 0.0 0.6 0.0 0.0 0.0 0.3 0.0 0.3 0.1 5.4 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 10.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.3 0.0 0.6 0.0 1.0 0.1 0.1 0.0 BLNK "BASH, bca, BLNK-s, Ly57, SLP-65, SLP65" ENSG00000095585 "B cell linker" Q8WV28 10 96189171-96271587 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "B-cell activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 70.5" "Cell type enhanced" "Detected in many" "B-cells: 94.2;dendritic cells: 64.0;Microglial cells: 157.4;Plasma cells: 80.4;Proximal enterocytes: 64.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "memory B-cell: 161.2;naive B-cell: 140.5;plasmacytoid DC: 231.5" "Group enriched" "Detected in many" 101 "B-cells: 161.2;dendritic cells: 231.5" "Group enriched" "Detected in some" 6 "Daudi: 68.7;REH: 168.4;RPMI-8226: 94.4;U-698: 251.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB009333, CAB016291, HPA038309, HPA038310" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "CAB009333: AB_2290422, CAB016291: AB_626752, HPA038309: AB_2675945, HPA038310: AB_2675946" "unprognostic (4.86e-2)" "unprognostic (6.05e-3)" "unprognostic (1.00e-2)" "unprognostic (2.73e-2)" "unprognostic (2.29e-1)" "unprognostic (1.63e-3)" "unprognostic (1.08e-2)" "unprognostic (5.19e-2)" "unprognostic (2.97e-1)" "unprognostic (1.02e-1)" "unprognostic (8.94e-2)" "unprognostic (3.73e-1)" "unprognostic (1.84e-2)" "unprognostic (5.23e-2)" "unprognostic (9.76e-2)" "unprognostic (1.46e-3)" "prognostic favorable (2.67e-6)" 2.2 3.2 3.8 27.5 3.4 10.1 6.3 2.4 4.1 7.1 13.9 16.9 38.9 2.4 30.1 39.9 6.1 10.8 1.0 3.5 5.1 28.5 39.2 6.6 57.6 4.7 4.0 1.5 12.1 17.4 1.8 6.4 5.0 7.3 18.2 1.4 10.9 13.2 0.5 8.0 34.0 3.0 3.8 54.0 29.2 1.3 4.9 10.6 11.6 1.1 70.5 9.9 15.8 5.2 0.3 0.1 0.1 0.2 0.0 0.1 0.8 0.1 0.0 0.0 0.0 0.2 0.2 68.7 0.4 0.0 0.3 0.6 0.1 0.8 0.1 5.5 0.2 0.3 0.3 0.1 0.0 0.1 1.4 0.1 8.7 0.0 0.0 0.1 0.0 0.8 0.3 6.4 0.0 0.7 0.4 0.2 0.2 0.2 0.0 168.4 0.3 94.4 0.9 13.0 0.3 0.3 0.2 15.1 0.1 0.2 23.7 1.1 0.2 0.2 0.8 0.1 0.2 5.4 0.4 251.4 0.1 0.5 0.1 0.3 1.6 0.2 0.3 1.3 0.1 161.2 0.3 0.2 20.6 140.5 0.1 0.1 1.1 1.9 0.1 231.5 0.6 8.1 3.8 3.4 2.4 4.1 3.5 5.1 4.7 4.0 5.0 3.8 4.9 5.2 0.4 6.4 7.7 0.7 94.2 1.1 21.0 13.1 21.1 0.0 4.1 3.4 1.2 30.0 7.3 40.5 0.0 23.0 64.0 9.2 27.4 14.6 3.1 14.4 1.9 0.3 4.9 5.3 1.0 13.8 17.5 0.7 35.7 22.9 1.3 0.0 2.9 27.8 22.8 0.0 1.3 19.4 30.5 9.0 13.8 1.1 0.3 18.2 1.8 157.4 4.8 0.0 0.0 2.5 0.9 4.4 22.4 0.0 80.4 5.1 64.6 2.3 3.4 0.0 6.6 0.3 0.7 1.6 0.1 34.7 1.4 41.5 3.6 0.5 22.5 23.8 BMPR2 "BMPR-II, BMPR3, BRK-3, PPH1, T-ALK" ENSG00000204217 "Bone morphogenetic protein receptor type 2" Q13873 2 202376327-202567751 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "Kinase, Receptor, Serine/threonine-protein kinase, Transferase" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 202.2;Inhibitory neurons: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017385, HPA049014" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA017385: AB_1845397, HPA049014: AB_2680599" "unprognostic (2.17e-1)" "unprognostic (9.00e-2)" "unprognostic (2.35e-1)" "unprognostic (2.73e-1)" "unprognostic (1.67e-1)" "unprognostic (2.55e-1)" "unprognostic (4.30e-2)" "unprognostic (1.11e-1)" "unprognostic (3.18e-2)" "unprognostic (1.10e-2)" "unprognostic (2.13e-2)" "unprognostic (1.97e-1)" "unprognostic (1.29e-2)" "unprognostic (1.21e-3)" "unprognostic (9.20e-2)" "unprognostic (1.18e-1)" "unprognostic (3.40e-1)" 18.5 21.6 8.2 10.9 14.1 2.2 13.2 3.2 16.8 22.6 0.3 13.6 8.5 20.0 11.3 12.4 14.9 17.3 21.5 16.0 14.8 17.4 15.6 29.1 7.2 6.2 7.7 16.8 10.4 17.5 8.5 34.0 10.0 17.1 13.0 26.7 11.0 13.9 10.9 10.9 8.6 24.3 3.9 13.1 11.7 11.3 10.6 9.0 18.2 23.1 9.4 20.6 12.4 5.9 13.3 12.3 12.6 19.7 34.2 31.9 23.8 27.2 28.3 23.6 23.9 10.8 19.6 4.7 30.7 58.2 19.9 24.5 16.8 21.4 41.6 13.8 11.2 14.2 12.6 16.8 22.7 4.0 10.7 24.2 21.5 17.1 22.8 40.6 73.9 5.6 9.3 22.5 33.8 24.8 3.4 3.6 6.9 6.6 11.1 9.1 24.3 7.1 21.3 27.9 12.6 12.7 28.9 17.7 32.7 32.0 13.2 9.5 75.9 48.0 24.4 16.3 16.7 3.1 4.1 1.3 11.3 9.0 13.9 0.1 0.6 0.2 0.9 0.5 0.6 0.3 0.3 0.5 0.6 0.4 0.7 0.3 0.1 0.3 0.9 0.7 1.0 0.3 8.2 14.1 3.2 16.8 16.0 14.8 6.2 7.7 10.0 3.9 10.6 5.9 116.9 105.8 40.3 104.5 15.2 33.4 18.0 34.9 13.6 54.3 29.2 29.7 55.5 15.7 38.8 20.2 81.3 16.9 17.8 25.2 1.9 27.2 2.8 23.1 54.5 152.2 25.1 6.9 202.2 28.1 22.6 47.7 16.8 36.4 23.5 155.1 143.1 19.9 18.7 35.3 190.2 16.3 20.3 24.2 31.7 4.6 33.8 23.5 42.7 170.5 20.2 39.9 16.5 152.8 55.1 46.8 21.1 42.9 9.5 23.9 16.4 12.4 28.0 31.7 65.7 48.8 62.4 33.2 25.0 21.2 35.9 20.0 13.1 0.8 15.5 24.8 BMX "ETK, PSCTK3" ENSG00000102010 "BMX non-receptor tyrosine kinase" P51813 X 15464246-15556529 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, Cell adhesion, Stress response" "Kinase, Transferase, Tyrosine-protein kinase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "epididymis: 102.6" "Group enriched" "Detected in some" 4 "Endothelial cells: 28.2;Hepatic stellate cells: 93.9" "Cancer enhanced" "Detected in many" "melanoma: 3.2" "Not detected" "Not detected" "Immune cell enriched" "Detected in single" 16 "neutrophil: 7.6" "Lineage enriched" "Detected in single" 77 "granulocytes: 7.6" "Cell line enriched" "Detected in some" 119 "HUVEC TERT2: 353.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001048, CAB032495" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "CAB032495: AB_2290760, HPA001048: AB_1078289" "unprognostic (7.80e-2)" "unprognostic (4.92e-3)" "unprognostic (1.16e-2)" "unprognostic (4.07e-3)" "unprognostic (2.69e-1)" "unprognostic (2.14e-1)" "unprognostic (1.06e-3)" "unprognostic (2.36e-1)" "unprognostic (1.87e-1)" "unprognostic (1.21e-1)" "unprognostic (1.78e-1)" "unprognostic (1.06e-1)" "unprognostic (1.26e-2)" "unprognostic (1.84e-2)" "unprognostic (3.64e-2)" "unprognostic (1.26e-1)" "unprognostic (2.81e-2)" 7.7 0.3 0.3 1.7 0.5 7.1 4.9 0.3 0.6 1.7 1.1 3.8 4.4 2.3 102.6 2.3 2.6 2.6 8.8 0.3 0.3 0.6 0.7 3.0 1.5 0.3 0.4 0.9 0.9 0.3 0.2 4.7 0.3 0.9 2.4 0.0 1.1 0.9 1.3 1.6 4.8 2.6 0.3 2.2 1.4 0.2 0.4 0.7 2.0 2.2 0.4 2.6 2.1 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 353.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.3 0.6 0.3 0.3 0.3 0.4 0.3 0.3 0.4 0.4 14.1 0.0 1.1 1.3 0.0 0.4 0.7 0.0 0.0 0.0 0.1 0.0 1.6 0.0 0.0 1.8 0.0 0.1 0.0 0.1 0.0 0.0 0.0 3.2 0.0 28.2 4.2 3.2 1.3 0.2 0.0 1.1 4.6 0.2 0.0 0.1 93.9 0.7 0.1 0.0 1.2 0.1 2.0 0.0 1.1 0.0 0.3 0.1 0.0 1.0 0.0 0.0 0.0 0.5 1.5 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.8 0.0 0.0 0.3 0.8 0.2 0.1 0.2 0.0 0.1 0.2 0.1 0.4 0.4 BORCS5 "LOH12CR1, LOH1CR12" ENSG00000165714 "BLOC-1 related complex subunit 5" Q969J3 12 12357078-12471233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 42.6;T-cells: 39.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039509, HPA043627" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "HPA039509: AB_2676550, HPA043627: AB_2678588" "unprognostic (1.82e-1)" "unprognostic (2.87e-1)" "unprognostic (2.81e-1)" "unprognostic (2.41e-1)" "unprognostic (8.00e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.47e-4)" "unprognostic (6.78e-2)" "unprognostic (6.16e-2)" "unprognostic (2.79e-2)" "unprognostic (6.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.12e-3)" "unprognostic (1.50e-2)" "unprognostic (2.14e-1)" "unprognostic (1.72e-1)" "unprognostic (9.51e-2)" 6.3 8.1 5.1 2.5 7.1 6.2 6.1 5.2 6.4 6.6 2.3 5.8 1.7 5.8 5.8 8.0 5.7 2.4 7.1 4.1 5.8 5.9 8.5 6.5 2.9 5.6 5.4 4.9 7.2 3.8 7.1 2.7 6.2 5.9 2.2 2.8 5.4 1.9 8.4 8.7 4.7 3.0 4.7 6.2 5.9 9.1 5.4 3.1 4.6 3.3 3.9 5.6 6.8 8.2 3.9 4.1 2.9 3.0 6.4 8.7 3.3 3.4 3.9 4.1 5.1 10.0 3.9 4.9 2.0 5.5 2.9 2.7 5.0 4.9 4.4 14.0 4.5 2.7 3.9 5.7 6.1 2.9 3.8 4.9 3.5 5.6 6.5 6.5 4.9 6.1 3.8 6.6 5.4 8.4 4.2 3.0 9.0 4.1 2.6 3.4 4.1 5.3 5.1 2.6 3.6 4.1 3.3 3.0 7.5 9.6 2.3 3.1 4.1 2.7 6.1 3.5 3.1 3.4 3.2 11.1 5.8 4.4 4.6 2.8 6.1 9.5 10.1 10.3 11.9 7.7 11.5 11.2 7.3 5.9 7.6 7.7 6.7 12.4 6.7 5.1 14.2 7.0 5.1 7.1 5.2 6.4 4.1 5.8 5.6 5.4 6.2 4.7 5.4 8.2 11.1 9.6 2.3 0.0 37.9 0.0 11.9 0.0 10.8 16.9 10.5 8.4 0.0 10.0 2.5 7.3 12.5 9.2 42.6 2.2 9.8 9.5 5.6 8.8 9.0 6.7 4.9 5.9 0.0 12.4 11.7 8.3 19.9 8.9 2.5 7.4 6.1 5.1 14.5 13.5 0.0 3.8 0.0 11.0 0.0 3.9 5.3 26.3 0.0 0.0 19.0 12.5 14.4 0.0 0.0 9.5 3.5 7.2 33.0 9.1 10.3 14.1 2.9 16.6 26.3 8.3 8.1 23.4 8.6 14.6 0.0 14.5 39.5 7.5 4.6 8.3 BRPF1 BR140 ENSG00000156983 "Bromodomain and PHD finger containing 1" P55201 3 9731729-9748015 "Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "BEWO: 82.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003359 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 28: BEWO - Transcription regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003359: AB_1078217" "unprognostic (4.18e-2)" "unprognostic (2.21e-2)" "unprognostic (6.47e-2)" "unprognostic (9.10e-2)" "unprognostic (3.42e-1)" "unprognostic (2.33e-2)" "prognostic unfavorable (3.20e-5)" "unprognostic (3.00e-1)" "unprognostic (3.72e-1)" "unprognostic (3.26e-3)" "unprognostic (4.27e-2)" "prognostic unfavorable (5.28e-4)" "unprognostic (1.51e-3)" "unprognostic (4.86e-2)" "unprognostic (3.55e-1)" "unprognostic (6.87e-2)" "unprognostic (9.67e-3)" 8.0 7.1 4.7 6.9 6.9 23.5 7.7 9.9 7.4 8.2 3.8 8.3 4.8 9.5 4.4 8.6 8.8 5.5 7.3 6.7 3.8 6.2 5.5 7.9 8.9 4.7 4.2 9.3 7.3 7.7 6.7 6.5 4.3 7.5 4.0 4.0 9.1 5.0 9.5 10.9 8.3 5.4 3.1 10.5 7.5 14.4 5.2 11.9 9.0 6.8 7.6 7.9 7.8 5.5 9.9 17.2 12.5 8.2 8.9 8.6 82.4 12.6 7.5 14.3 10.2 12.1 8.3 18.6 6.0 11.6 13.5 8.2 15.3 12.0 9.0 20.1 17.9 21.4 33.8 9.8 11.4 30.6 20.0 8.5 9.8 19.8 13.1 7.2 10.8 17.5 25.2 15.9 8.3 24.3 19.8 25.7 20.6 6.7 15.9 28.7 10.6 12.3 6.7 14.5 8.9 15.2 12.7 9.0 10.1 8.2 9.8 31.4 14.1 15.9 13.6 14.5 24.0 13.4 18.1 31.5 13.1 25.9 15.1 1.0 0.9 1.4 1.3 0.8 2.0 0.6 0.9 1.2 0.8 0.5 1.1 1.3 0.8 4.2 0.7 1.9 0.7 0.8 4.7 6.9 9.9 7.4 6.7 3.8 4.7 4.2 4.3 3.1 5.2 5.5 7.9 16.0 10.0 2.6 6.8 14.1 5.1 3.9 8.0 4.6 9.2 7.0 3.7 2.8 6.2 7.3 6.2 4.2 13.0 9.4 0.0 4.1 3.9 4.2 6.9 9.7 10.2 9.7 3.4 5.5 5.5 5.8 7.7 7.0 8.8 7.3 11.0 3.5 6.4 8.4 2.4 5.0 2.0 5.6 9.2 1.2 6.5 6.9 1.8 2.8 6.3 5.2 5.2 4.0 2.9 6.1 3.1 6.0 7.9 5.1 4.9 2.1 4.3 5.1 6.6 11.3 7.7 16.6 13.9 9.9 18.5 3.7 10.8 5.6 6.1 6.8 BSDC1 "FLJ10276, RP4-811H24.7" ENSG00000160058 "BSD domain containing 1" Q9NW68 1 32364633-32394731 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 37.4" "Lineage enriched" "Detected in all" 4 "granulocytes: 37.4" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031358, HPA031360" Approved Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA031358: AB_2673841, HPA031360: AB_10601120" "unprognostic (1.42e-1)" "unprognostic (8.97e-2)" "unprognostic (2.91e-2)" "unprognostic (3.86e-2)" "unprognostic (2.48e-1)" "prognostic favorable (8.82e-5)" "unprognostic (3.40e-1)" "unprognostic (2.06e-2)" "unprognostic (1.61e-1)" "unprognostic (1.04e-1)" "unprognostic (9.56e-3)" "unprognostic (5.92e-2)" "unprognostic (1.95e-3)" "unprognostic (1.92e-3)" "unprognostic (2.68e-1)" "unprognostic (2.37e-1)" "unprognostic (2.07e-1)" 36.8 63.0 28.0 17.4 29.4 77.1 37.8 31.7 30.6 38.7 27.3 35.9 25.4 35.3 24.9 36.7 35.3 23.3 35.9 28.9 27.2 38.7 73.2 33.7 22.4 32.5 27.8 54.5 56.0 42.3 46.5 22.1 28.8 41.0 22.5 21.7 45.0 24.3 36.7 47.5 34.8 20.7 28.1 35.8 41.0 51.3 28.4 19.5 37.9 16.3 21.8 33.2 36.5 35.9 24.3 16.2 32.8 25.2 38.6 29.6 25.6 23.0 43.9 39.8 41.0 18.1 19.9 17.8 27.0 41.3 22.6 26.1 23.4 21.6 25.6 33.4 33.3 14.2 35.5 22.1 33.2 17.6 24.7 35.5 46.4 30.7 23.2 47.8 24.8 28.0 36.4 30.8 22.3 10.7 18.7 10.3 20.8 14.1 19.0 18.8 18.8 24.7 22.6 19.5 34.6 25.0 22.1 22.7 25.2 37.7 21.4 13.9 30.1 22.1 19.8 28.3 22.6 42.2 41.6 15.9 25.8 22.3 13.5 37.4 5.1 18.3 6.2 5.9 6.1 7.0 5.5 5.2 4.9 8.3 6.0 5.6 8.4 6.1 5.0 6.5 7.3 6.2 28.0 29.4 31.7 30.6 28.9 27.2 32.5 27.8 28.8 28.1 28.4 35.9 24.6 32.1 18.6 23.5 42.8 28.4 56.6 31.5 25.6 53.6 38.9 26.7 19.4 55.8 21.9 25.8 83.4 51.1 38.8 59.3 19.6 37.8 88.9 23.7 26.3 35.2 40.1 76.0 25.6 44.1 31.0 32.7 27.0 34.4 21.0 36.1 50.0 56.7 20.0 85.8 31.6 47.8 28.5 25.8 13.1 100.7 54.7 20.1 32.0 25.3 28.0 30.3 57.7 29.1 35.0 45.6 40.0 47.4 32.1 58.4 63.9 28.0 18.4 69.8 39.5 33.1 38.1 42.9 45.9 21.2 25.9 96.5 34.6 60.5 39.3 57.2 BTK "AGMX1, ATK, IMD1, PSCTK1, XLA" ENSG00000010671 "Bruton tyrosine kinase" Q06187 X 101349447-101390796 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Apoptosis, Immunity, Innate immunity, Transcription, Transcription regulation" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.6;lymphoid tissue: 78.0" "Cell type enhanced" "Detected in some" "B-cells: 84.7;granulocytes: 211.4;Hofbauer cells: 56.6;Kupffer cells: 63.5;Macrophages: 61.1;monocytes: 71.1;Plasma cells: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 557.5" "Lineage enriched" "Detected in many" 4 "granulocytes: 557.5" "Cell line enhanced" "Detected in some" "Daudi: 206.7;HEL: 287.4;HMC-1: 990.3;U-937: 149.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA001198, HPA002028, CAB016689" Enhanced Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 38: Basophils - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "CAB016689: AB_1611894, HPA001198: AB_1078305, HPA002028: AB_1078306" "unprognostic (3.19e-2)" "unprognostic (2.51e-3)" "unprognostic (1.06e-2)" "unprognostic (3.66e-2)" "unprognostic (5.69e-2)" "unprognostic (3.76e-3)" "unprognostic (6.55e-2)" "unprognostic (3.58e-3)" "unprognostic (6.02e-2)" "unprognostic (3.12e-1)" "unprognostic (1.02e-1)" "unprognostic (1.41e-1)" "unprognostic (2.08e-3)" "unprognostic (7.80e-2)" "unprognostic (1.29e-2)" "unprognostic (1.56e-2)" "unprognostic (8.14e-2)" 6.3 2.9 2.3 30.7 2.6 32.6 4.4 2.8 3.4 3.9 3.1 6.6 4.8 2.5 1.5 3.6 1.9 7.6 1.6 2.3 3.1 1.3 5.4 19.6 55.5 4.7 3.6 0.8 1.2 0.9 0.9 7.0 4.7 1.9 9.1 0.3 2.8 2.3 0.6 2.9 14.7 7.1 3.8 38.4 7.0 1.4 3.9 9.3 1.3 2.0 78.0 9.3 1.5 6.5 0.1 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 206.7 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.3 287.4 0.0 0.0 0.0 116.7 990.3 0.0 0.0 0.1 0.0 0.0 0.0 0.2 61.9 2.3 0.0 0.0 0.6 81.5 1.6 0.0 0.0 87.2 0.1 13.2 0.0 0.0 0.2 0.0 0.3 0.1 0.5 1.0 0.0 68.5 0.4 0.0 0.3 0.2 0.1 2.6 1.4 98.3 0.5 149.8 0.3 557.5 62.2 110.5 0.2 99.9 0.2 72.4 0.2 0.1 72.7 73.0 0.4 0.1 24.7 0.2 123.9 33.1 0.1 38.4 2.3 2.6 2.8 3.4 2.3 3.1 4.7 3.6 4.7 3.8 3.9 6.5 1.5 3.2 8.9 0.3 84.7 1.0 0.2 0.0 0.6 0.0 0.9 1.4 0.6 0.0 0.6 0.0 0.0 1.4 30.1 0.1 0.0 0.0 0.2 1.3 0.3 0.8 0.0 27.1 0.5 0.0 0.5 0.9 1.1 2.3 211.4 0.0 0.7 0.3 56.6 0.0 0.3 0.3 0.0 63.5 31.0 0.1 0.3 61.1 3.6 10.3 71.1 0.0 2.1 0.0 0.1 0.1 0.5 0.0 43.8 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.5 0.7 1.7 0.5 0.3 1.9 5.7 0.2 0.1 0.1 BVES "HBVES, POP1, POPDC1" ENSG00000112276 "Blood vessel epicardial substance" Q8NE79 6 105096822-105137157 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cell adhesion" "Developmental protein" "Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 27.8;skeletal muscle: 43.9;tongue: 29.3" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 34.2;Early spermatids: 36.1;Late spermatids: 55.3;Oligodendrocytes: 17.8;Spermatocytes: 24.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "RH-30: 29.7;WM-115: 30.2" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA014788, HPA018176" Enhanced Supported "Plasma membrane,Cell Junctions" Yes NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA014788: AB_1845504, HPA018176: AB_1845503" "unprognostic (2.91e-1)" "unprognostic (2.45e-1)" "unprognostic (2.79e-2)" "unprognostic (1.73e-2)" "unprognostic (5.46e-2)" "unprognostic (3.66e-2)" "unprognostic (5.21e-2)" "unprognostic (2.22e-2)" "unprognostic (8.37e-2)" "unprognostic (4.49e-2)" "unprognostic (2.29e-2)" "unprognostic (8.92e-2)" "unprognostic (5.84e-3)" "unprognostic (3.77e-2)" "unprognostic (1.78e-1)" "unprognostic (2.02e-2)" "unprognostic (3.24e-4)" 2.9 0.7 2.6 2.3 7.1 0.2 1.5 5.8 3.6 2.5 4.6 14.9 1.4 5.8 1.7 5.3 2.8 1.8 27.8 2.7 4.3 1.6 0.3 1.9 0.6 7.3 5.6 1.0 0.6 0.7 2.4 3.5 7.4 5.2 3.3 0.2 1.4 10.0 43.9 0.7 3.0 17.7 5.2 0.3 6.9 11.5 5.2 0.2 1.3 29.3 0.4 9.3 2.2 10.8 1.3 2.0 7.6 1.3 10.9 14.9 3.3 5.8 4.1 8.8 11.6 0.5 0.0 0.0 0.0 10.9 14.7 0.1 3.3 2.0 8.1 0.0 2.8 0.0 1.0 0.3 2.4 0.0 0.6 8.7 6.9 13.6 1.1 6.6 4.0 3.3 0.1 19.3 19.7 0.1 0.2 1.0 1.6 0.0 0.0 5.7 29.7 0.0 0.0 0.0 9.9 17.1 3.7 0.1 7.7 5.5 0.0 20.0 8.9 14.0 0.0 0.0 15.3 1.8 0.8 0.0 8.3 0.0 30.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.0 2.6 7.1 5.8 3.6 2.7 4.3 7.3 5.6 7.4 5.2 5.2 10.8 2.1 0.0 0.0 1.6 0.0 0.3 0.4 0.1 0.6 0.0 0.4 1.0 34.2 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 36.1 1.9 4.4 3.1 0.0 0.0 3.3 0.0 0.2 2.6 0.0 6.0 0.0 0.9 2.2 0.1 2.3 0.0 0.6 0.0 0.0 0.0 1.9 55.3 1.2 0.5 0.0 3.7 1.0 0.0 0.0 5.0 17.8 0.1 0.0 3.4 0.0 0.5 0.1 0.1 0.1 0.0 13.1 11.8 4.4 24.4 5.4 0.1 0.9 0.1 0.2 1.3 0.0 0.3 C12orf76 FLJ40142 ENSG00000174456 "Chromosome 12 open reading frame 76" 12 110027028-110073634 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in all" "brain: 77.2;choroid plexus: 44.0" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 174.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "basophil: 60.0" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" HPA039713 Uncertain Approved "Plasma membrane,Actin filaments" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 51: Myeloid cells - Hemostasis" "Actin filaments" "Plasma membrane" "HPA039713: AB_2676640" "unprognostic (9.20e-2)" "unprognostic (3.31e-2)" "unprognostic (2.35e-3)" "unprognostic (9.54e-2)" "unprognostic (3.50e-2)" "unprognostic (1.14e-1)" "unprognostic (1.75e-2)" "prognostic favorable (6.44e-5)" "unprognostic (1.39e-1)" "unprognostic (1.47e-1)" "unprognostic (8.86e-3)" "unprognostic (1.75e-1)" "prognostic unfavorable (5.74e-5)" "unprognostic (2.09e-1)" "unprognostic (7.85e-2)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" 4.0 5.0 58.2 5.4 61.5 2.4 7.4 67.2 76.0 6.8 44.0 6.2 3.5 5.6 9.9 3.9 10.3 3.7 4.0 59.5 61.6 8.4 10.1 8.0 8.5 64.9 63.6 8.4 6.4 3.9 10.2 8.0 67.3 6.7 4.7 16.6 5.0 5.1 6.7 4.6 5.7 3.4 60.0 9.2 4.6 8.3 61.3 7.1 9.6 4.1 6.1 5.5 5.4 77.2 3.8 7.5 10.7 8.8 5.2 12.2 10.9 3.4 3.0 7.3 5.0 4.8 4.3 8.1 4.6 1.8 5.0 8.8 4.2 5.4 5.0 9.8 9.9 8.5 7.2 13.3 7.2 13.6 16.2 13.7 14.9 4.7 11.3 19.7 10.7 13.4 13.0 3.0 5.4 4.1 4.3 25.2 9.4 5.1 6.1 10.5 7.0 12.5 11.2 4.1 26.4 12.5 5.3 2.8 11.1 13.3 8.4 6.2 6.2 3.5 4.9 3.4 1.5 8.4 12.8 4.4 8.2 6.3 3.5 60.0 10.2 11.0 6.4 7.8 9.2 18.6 12.7 7.1 10.9 11.6 17.4 10.2 5.8 18.8 5.2 9.7 12.8 12.0 58.2 61.5 67.2 76.0 59.5 61.6 64.9 63.6 67.3 60.0 61.3 77.2 22.5 32.1 17.0 13.4 15.2 7.9 16.2 18.7 13.6 26.4 24.9 39.8 7.1 18.6 10.5 16.5 2.1 30.2 13.3 6.4 35.2 11.6 31.0 42.3 18.7 18.3 6.1 14.5 32.0 15.1 10.5 17.7 6.6 17.4 5.1 22.8 21.8 22.4 26.4 32.0 28.5 10.7 16.2 24.2 13.1 13.5 26.1 35.9 19.6 15.0 25.3 39.4 24.7 53.3 174.6 11.8 7.5 33.8 10.2 11.7 13.3 38.6 33.9 20.9 6.6 16.4 16.5 25.2 11.3 9.0 8.5 12.0 21.8 15.4 9.5 9.8 C14orf93 "FLJ12154, RTFC" ENSG00000100802 "Chromosome 14 open reading frame 93" Q9H972 14 22985894-23010166 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002569 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 57: B-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA002569: AB_1078334" "prognostic favorable (5.05e-4)" "unprognostic (1.31e-2)" "unprognostic (2.97e-2)" "unprognostic (2.23e-3)" "unprognostic (2.30e-2)" "unprognostic (1.30e-1)" "unprognostic (1.24e-2)" "unprognostic (1.02e-1)" "unprognostic (1.88e-1)" "unprognostic (1.29e-1)" "unprognostic (4.86e-3)" "unprognostic (7.45e-2)" "unprognostic (2.01e-3)" "unprognostic (1.10e-1)" "unprognostic (2.49e-1)" "unprognostic (2.14e-1)" "unprognostic (7.11e-2)" 8.3 4.8 6.5 5.7 7.7 12.6 8.2 6.7 7.0 11.2 8.5 8.8 7.4 8.7 11.4 7.4 9.5 9.2 5.6 6.2 7.3 11.1 8.9 6.7 10.1 7.7 7.2 10.3 9.6 8.3 6.5 5.0 7.5 9.6 9.6 4.4 8.0 5.7 6.7 18.3 8.1 6.8 6.7 10.6 8.3 4.0 7.2 15.7 11.5 7.9 10.5 8.6 8.3 9.5 5.7 10.5 8.8 12.3 13.9 30.8 12.2 6.6 10.2 5.1 6.7 6.6 16.5 16.0 6.1 6.0 7.2 11.8 5.4 16.6 4.7 6.3 3.8 10.1 14.0 15.3 12.1 7.4 8.3 22.4 12.8 7.6 9.6 18.5 9.6 10.1 11.1 3.4 5.3 16.3 9.5 13.6 3.0 12.3 7.3 15.1 8.4 9.8 6.7 8.6 31.8 13.8 8.8 8.4 9.0 9.4 13.0 12.8 5.5 9.6 12.7 4.3 6.7 11.9 3.6 11.0 6.6 9.1 10.0 12.2 7.7 22.9 8.1 7.4 7.2 10.4 6.5 8.5 9.1 10.0 9.8 9.4 11.2 10.4 13.0 6.3 13.4 7.1 6.5 7.7 6.7 7.0 6.2 7.3 7.7 7.2 7.5 6.7 7.2 9.5 3.1 9.6 1.1 14.7 8.7 3.1 4.1 4.6 10.2 1.4 4.0 4.1 3.3 1.5 2.6 0.0 4.2 4.3 7.8 3.7 7.9 3.9 0.8 3.3 2.6 3.3 15.7 6.5 3.4 3.0 5.7 3.9 7.7 3.0 7.0 4.7 1.4 1.5 3.8 0.0 3.4 6.3 4.1 5.5 2.5 1.5 4.4 3.4 5.4 9.4 1.9 4.1 7.2 7.1 9.9 3.1 7.3 4.1 5.2 1.9 4.6 3.6 4.6 2.0 6.6 3.8 3.7 2.9 8.2 5.3 1.6 3.0 5.2 4.1 5.1 2.5 C16orf74 MGC17624 ENSG00000154102 "Chromosome 16 open reading frame 74" Q96GX8 16 85690084-85751129 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.7" "Cell type enhanced" "Detected in many" "B-cells: 47.4;Basal prostatic cells: 56.7;Bipolar cells: 55.8;Cone photoreceptor cells: 58.4;Rod photoreceptor cells: 87.8;Syncytiotrophoblasts: 74.3;Urothelial cells: 55.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HBEC3-KT: 96.1;hTCEpi: 80.8;T-47d: 84.5" HPA049367 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 37: B-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 57: B-cells - Immune response" "Plasma membrane" Centrosome "HPA049367: AB_2680730" "unprognostic (1.16e-1)" "unprognostic (2.21e-2)" "unprognostic (6.74e-3)" "unprognostic (2.15e-3)" "unprognostic (3.65e-2)" "prognostic unfavorable (1.71e-4)" "unprognostic (1.08e-3)" "unprognostic (4.22e-3)" "prognostic unfavorable (4.08e-4)" "unprognostic (5.06e-2)" "prognostic unfavorable (1.54e-5)" "unprognostic (3.40e-1)" "unprognostic (1.76e-3)" "unprognostic (2.51e-1)" "unprognostic (3.55e-1)" "unprognostic (2.15e-2)" "unprognostic (9.07e-3)" 3.6 0.7 8.4 4.3 8.5 8.9 6.5 6.8 12.0 9.5 7.8 3.1 1.4 1.5 2.0 9.4 1.5 2.2 2.2 12.2 7.4 2.5 1.1 2.2 8.4 7.5 7.4 0.8 1.8 7.5 1.3 6.7 7.0 9.2 1.1 27.7 4.2 7.3 0.5 9.0 5.6 0.9 6.7 16.0 2.9 2.1 7.6 1.4 5.0 0.3 6.4 17.2 14.5 7.4 35.3 11.5 0.4 4.7 5.1 5.6 14.1 4.2 5.6 13.1 3.7 8.9 32.1 0.3 47.2 3.3 5.5 49.4 2.0 96.1 7.4 0.0 7.6 0.0 5.3 0.9 13.9 1.0 0.0 12.2 80.8 12.6 54.7 9.8 43.4 5.8 0.0 0.2 0.4 29.6 0.0 54.0 2.9 37.7 32.6 1.4 0.0 2.8 0.1 39.5 10.7 2.8 17.5 8.9 9.1 3.6 84.5 14.9 44.8 8.4 22.0 3.8 12.7 11.7 9.3 40.0 0.0 12.6 1.7 0.1 16.8 21.8 1.3 6.3 4.4 46.7 8.8 7.0 18.3 49.4 14.5 9.3 6.6 7.8 2.0 0.3 18.0 10.8 8.4 8.5 6.8 12.0 12.2 7.4 7.5 7.4 7.0 6.7 7.6 7.4 10.1 3.2 1.1 6.5 47.4 9.3 56.7 23.8 8.0 55.8 19.0 20.3 1.8 1.5 9.8 1.8 58.4 45.8 3.4 0.1 3.9 3.0 1.7 4.4 4.6 7.2 0.0 0.8 0.4 1.1 19.7 5.7 1.5 4.1 0.0 0.5 2.5 0.0 5.0 15.2 0.4 0.0 8.2 1.2 2.9 0.4 3.4 2.5 19.6 1.0 5.2 18.8 4.1 1.5 0.8 3.2 0.0 3.4 44.2 36.5 0.0 2.4 3.9 87.8 0.0 0.3 2.5 0.9 8.4 8.5 7.0 74.3 3.7 1.5 0.2 55.7 C17orf58 ENSG00000186665 "Chromosome 17 open reading frame 58" Q2M2W7 17 67991099-67996469 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 35.6" "Cell type enhanced" "Detected in many" "Fibroblasts: 51.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 55.5" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 37.3" HPA023036 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA023036: AB_10601144" "unprognostic (1.41e-1)" "unprognostic (1.22e-1)" "unprognostic (6.66e-2)" "unprognostic (1.35e-1)" "unprognostic (1.00e-1)" "unprognostic (7.65e-3)" "prognostic unfavorable (8.99e-4)" "unprognostic (7.45e-2)" "unprognostic (2.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.22e-2)" "unprognostic (6.69e-2)" "prognostic unfavorable (1.31e-10)" "unprognostic (1.16e-2)" "unprognostic (1.04e-1)" "unprognostic (5.00e-2)" "unprognostic (1.01e-1)" 11.9 5.4 5.2 2.8 5.5 3.9 16.9 5.4 10.0 26.8 4.8 8.4 4.0 15.1 6.9 5.1 7.8 4.7 5.9 5.7 5.3 6.1 9.4 3.4 3.2 5.4 5.3 4.8 4.8 3.2 2.0 35.6 5.1 5.8 7.3 8.9 4.3 3.6 3.5 3.5 4.6 10.9 5.5 2.3 6.8 3.0 5.2 2.1 6.8 7.3 7.1 8.8 7.6 5.5 9.8 9.5 9.3 11.6 6.6 16.6 7.3 4.0 11.4 6.9 11.2 5.6 12.4 13.0 8.9 3.3 12.1 4.9 21.3 8.6 16.6 23.5 21.5 8.4 3.2 17.8 10.4 7.2 14.9 9.2 10.2 6.7 15.4 7.7 32.7 11.2 18.2 19.6 6.7 13.1 1.3 9.5 10.7 23.6 10.0 3.1 10.2 17.4 8.7 6.5 6.9 12.5 6.0 55.5 20.8 11.4 15.8 8.2 6.1 5.8 5.9 4.2 8.5 38.9 30.9 11.6 14.8 12.6 10.5 8.6 2.8 5.0 2.2 2.9 0.7 3.0 0.8 1.7 3.9 0.5 0.3 0.8 1.1 2.7 5.0 0.1 0.4 1.8 5.2 5.5 5.4 10.0 5.7 5.3 5.4 5.3 5.1 5.5 5.2 5.5 21.6 0.0 1.7 6.2 3.5 4.8 5.5 5.6 7.4 8.9 31.0 21.8 4.7 12.8 6.1 11.0 10.4 28.6 4.1 10.5 23.5 10.1 0.9 21.0 40.5 16.3 3.6 8.4 5.0 9.3 21.7 51.6 19.9 19.4 12.7 3.8 14.3 18.5 16.9 5.0 4.6 15.0 10.2 9.7 21.5 2.8 3.7 7.3 8.8 2.8 18.4 31.9 12.3 3.0 4.6 10.7 10.0 5.3 7.0 11.6 10.9 19.7 16.5 15.6 6.6 36.2 14.1 7.3 6.0 20.7 8.4 15.3 4.1 8.3 10.1 7.6 C18orf21 "HsT3108, PNAS-124, PNAS-131" ENSG00000141428 "Chromosome 18 open reading frame 21" Q32NC0 18 35972625-35979286 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 145.2;Late spermatids: 76.3;Spermatocytes: 124.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065505, HPA067322" Uncertain Approved "Nucleoli,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoli, Plasma membrane" "HPA065505: AB_2685498, HPA067322: AB_2685822" "unprognostic (7.31e-2)" "unprognostic (2.14e-3)" "unprognostic (9.88e-2)" "unprognostic (8.66e-3)" "unprognostic (2.04e-1)" "unprognostic (1.77e-1)" "prognostic unfavorable (1.38e-6)" "unprognostic (2.53e-3)" "unprognostic (1.83e-2)" "prognostic favorable (1.81e-6)" "unprognostic (2.88e-2)" "unprognostic (1.24e-1)" "unprognostic (1.16e-1)" "unprognostic (1.21e-2)" "unprognostic (5.15e-3)" "unprognostic (2.35e-3)" "unprognostic (5.97e-2)" 16.4 18.2 15.2 12.8 15.7 71.9 20.5 18.6 19.7 13.6 14.2 15.1 16.2 15.3 18.4 14.7 14.9 12.3 18.3 15.4 15.2 15.1 16.9 12.2 21.8 15.0 15.0 17.0 23.2 17.9 12.9 14.6 15.0 14.4 13.1 19.2 19.3 12.9 34.1 16.3 15.2 13.0 15.6 18.1 19.8 35.8 15.4 21.9 14.0 26.4 18.8 16.3 12.3 16.5 24.9 17.2 35.3 27.0 25.4 36.2 25.9 34.3 34.9 42.3 44.7 15.8 17.8 22.4 33.7 27.4 26.9 26.2 28.2 28.8 45.7 33.4 30.4 22.5 21.2 35.5 35.3 65.4 26.3 37.9 46.7 38.2 39.3 36.8 37.0 30.6 39.7 34.0 29.4 29.5 42.4 48.0 30.4 11.6 18.9 28.0 30.7 43.0 29.2 29.5 25.5 36.0 25.4 18.8 58.3 32.7 28.2 31.2 24.3 43.3 19.1 15.8 31.0 43.2 41.4 46.0 21.4 37.3 22.1 97.5 28.8 34.2 24.5 30.7 24.2 34.7 25.9 23.2 27.1 30.9 19.8 25.9 28.0 28.8 30.0 26.6 41.5 19.8 15.2 15.7 18.6 19.7 15.4 15.2 15.0 15.0 15.0 15.6 15.4 16.5 9.6 19.2 6.1 3.9 13.7 11.9 8.9 17.4 18.2 9.6 13.1 16.5 12.7 10.0 12.1 1.8 6.2 19.0 23.0 10.4 11.7 20.2 145.2 13.7 14.7 10.8 7.2 12.4 5.5 28.8 32.0 12.4 8.6 14.4 14.0 12.9 10.0 9.6 21.3 8.4 6.0 12.9 16.2 20.1 10.3 76.3 22.4 14.4 12.4 5.6 24.4 13.1 20.6 4.5 5.1 20.0 14.0 17.0 13.5 11.7 17.8 20.1 5.1 12.1 0.0 14.1 11.3 124.0 35.9 12.8 12.4 13.1 13.6 17.3 15.9 9.3 C1orf116 "FLJ36507, MGC2742, MGC4309, SARG" ENSG00000182795 "Chromosome 1 open reading frame 116" Q9BW04 1 207018522-207032756 "Predicted intracellular proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 102.3;lung: 72.9;stomach 1: 58.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 176.3;Alveolar cells type 2: 99.4;Club cells: 68.5;Urothelial cells: 128.1" "Cancer enhanced" "Detected in many" "prostate cancer: 65.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 57.7;CAPAN-2: 99.5;HaCaT: 123.1;HBEC3-KT: 118.6;hTCEpi: 61.4;RPTEC TERT1: 56.4" "Low region specificity" "Detected in all" "Not detected" "Not detected" "HPA011888, HPA011889" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 180000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA011888: AB_1853872, HPA011889: AB_1853873" "unprognostic (1.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.95e-2)" "unprognostic (1.68e-1)" "unprognostic (2.35e-1)" "unprognostic (5.78e-2)" "unprognostic (3.27e-1)" "unprognostic (5.19e-2)" "unprognostic (8.07e-2)" "unprognostic (4.18e-2)" "unprognostic (2.87e-3)" "unprognostic (7.09e-3)" "prognostic favorable (1.01e-5)" "unprognostic (5.17e-1)" "unprognostic (2.48e-1)" "unprognostic (7.57e-3)" "unprognostic (1.19e-1)" 0.2 0.4 0.0 1.6 0.0 0.8 10.4 0.0 0.1 15.1 0.0 8.9 24.5 0.2 0.7 102.3 2.6 9.8 0.5 0.0 0.0 8.4 0.5 72.9 0.0 0.0 0.0 0.1 12.9 0.0 0.3 0.2 0.0 50.9 8.4 0.0 29.4 1.9 0.5 37.7 20.3 0.3 0.0 0.2 58.7 0.9 0.0 0.3 4.2 0.5 16.1 20.6 31.2 0.0 57.7 7.7 0.0 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 5.1 99.5 0.0 6.5 0.0 0.0 123.1 0.0 118.6 0.0 0.1 0.0 10.6 1.0 1.6 0.0 0.0 0.6 0.0 61.4 0.0 34.2 0.0 0.0 0.2 6.9 0.1 0.0 0.1 0.1 0.2 0.1 37.3 3.3 0.0 0.0 0.2 56.4 15.1 0.1 0.3 1.1 11.1 0.5 0.4 0.2 0.2 0.0 0.0 0.3 0.1 0.3 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 176.3 99.4 0.0 0.3 20.8 53.0 26.8 10.8 0.0 5.4 7.2 49.9 30.0 68.5 11.0 0.0 0.1 0.1 40.7 15.6 24.3 5.7 6.7 1.4 1.7 10.7 0.0 0.1 24.4 0.0 1.6 50.4 14.9 6.3 0.0 0.0 0.0 0.2 0.0 0.1 19.8 12.2 0.0 1.2 5.5 0.3 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.1 60.7 35.3 0.0 0.3 56.5 31.8 0.3 41.0 0.0 0.0 0.0 2.8 0.1 0.0 24.3 23.3 0.0 0.3 0.1 8.9 128.1 C1orf68 "LEP7, XP32" ENSG00000198854 "Chromosome 1 open reading frame 68" Q5T750 1 152719522-152720470 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 16 "skin 1: 678.3" "Cell type enriched" "Detected in some" 14 "Suprabasal keratinocytes: 78.3" "Group enriched" "Detected in some" 13 "head and neck cancer: 2.4;melanoma: 6.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 5 "HaCaT: 1.8" "Not detected" "Not detected" HPA057942 Approved "Plasma membrane,Cytosol" NA NA 220000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane" Cytosol "HPA057942: " "unprognostic (1.73e-1)" "unprognostic (7.46e-2)" "unprognostic (9.34e-2)" 0.4 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 678.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.8 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 78.3 0.0 0.1 0.0 0.0 0.0 C1orf74 "FLJ25078, URLC4" ENSG00000162757 "Chromosome 1 open reading frame 74" Q96LT6 1 209779208-209784559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 6.7" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 14.9;Glandular and luminal cells: 28.4;Squamous epithelial cells: 25.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028496 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA028496: AB_10602698" "unprognostic (3.25e-1)" "prognostic unfavorable (8.52e-6)" "unprognostic (8.41e-3)" "unprognostic (9.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" "unprognostic (1.75e-2)" "unprognostic (9.98e-2)" "unprognostic (3.82e-2)" "unprognostic (1.39e-2)" "unprognostic (4.95e-1)" "unprognostic (2.81e-1)" "unprognostic (6.31e-2)" "unprognostic (1.10e-1)" "unprognostic (2.67e-2)" "unprognostic (1.07e-1)" "unprognostic (5.40e-2)" 0.6 0.9 0.7 2.4 0.7 1.1 2.2 1.8 0.7 0.9 0.2 1.6 1.3 0.8 2.0 4.0 1.1 0.9 1.5 0.7 0.9 1.9 1.7 0.9 4.3 0.8 0.8 0.9 0.8 1.2 0.8 1.1 0.8 1.6 2.0 0.9 1.9 0.9 1.0 6.7 2.8 0.6 0.7 4.2 1.7 1.3 1.1 2.1 1.2 0.9 2.4 1.9 1.7 0.8 4.7 2.4 1.5 0.8 2.0 2.3 3.5 2.6 3.4 3.1 3.2 4.9 3.5 4.9 1.5 1.7 1.9 9.3 0.9 7.6 3.6 4.9 3.1 3.2 1.7 0.4 2.8 4.6 1.4 1.4 6.6 3.9 6.3 2.6 1.8 6.6 6.5 3.5 2.7 2.4 3.9 4.7 6.4 3.2 4.1 4.0 7.2 6.9 2.7 4.0 6.0 6.5 3.5 2.7 4.0 3.4 4.2 2.4 1.7 2.6 3.1 2.7 4.2 3.2 3.4 5.4 2.3 3.7 3.8 4.7 0.8 0.7 1.3 0.9 0.9 1.8 0.6 1.0 1.6 3.7 1.1 1.2 0.5 1.5 0.5 2.7 0.6 0.9 0.7 0.7 1.8 0.7 0.7 0.9 0.8 0.8 0.8 0.7 1.1 0.8 0.6 3.2 2.2 0.0 1.1 2.2 6.1 4.6 6.8 1.6 3.7 2.8 2.0 0.0 1.8 0.0 0.0 3.9 1.5 3.5 7.9 1.9 0.1 14.9 1.8 0.8 3.6 2.1 0.5 2.0 5.0 0.9 2.6 28.4 1.3 2.2 1.4 2.3 2.8 1.7 0.6 5.9 0.0 1.3 0.3 0.6 2.5 1.6 0.0 1.0 1.3 2.2 0.0 0.0 0.3 4.1 3.5 0.0 0.6 5.1 2.4 7.4 1.8 1.3 0.0 0.4 1.0 3.6 4.7 25.0 4.8 4.0 1.1 2.8 3.4 12.1 C1QBP "gC1Q-R, gC1qR, HABP1, p32, SF2p32" ENSG00000108561 "Complement C1q binding protein" Q07021 17 5432777-5448830 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins, Transporters" "Adaptive immunity, Apoptosis, Complement pathway, Host-virus interaction, Immunity, Innate immunity, mRNA processing, mRNA splicing, Ribosome biogenesis, Transcription, Transcription regulation" "Cancer-related genes, Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026483 Supported Approved "Plasma membrane,Mitochondria" "Secreted to blood" NA NA 410000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Mitochondria "HPA026483: AB_1847108" "unprognostic (2.18e-1)" "unprognostic (1.74e-1)" "unprognostic (3.80e-2)" "unprognostic (6.40e-2)" "unprognostic (2.60e-1)" "unprognostic (6.76e-2)" "unprognostic (7.47e-2)" "unprognostic (4.62e-2)" "unprognostic (2.40e-3)" "unprognostic (6.03e-2)" "unprognostic (4.60e-3)" "unprognostic (3.08e-2)" "unprognostic (7.80e-3)" "unprognostic (1.20e-1)" "unprognostic (3.13e-1)" "unprognostic (3.28e-1)" "unprognostic (3.97e-1)" 79.3 135.4 85.5 84.1 85.7 121.2 108.7 91.5 118.3 58.4 119.6 140.3 95.9 66.4 68.3 138.6 74.5 48.7 126.3 89.5 94.3 136.4 134.5 54.7 115.7 89.6 92.3 52.7 72.9 127.7 81.3 75.8 93.2 63.9 141.6 86.7 66.2 73.1 174.2 81.3 78.4 80.9 93.1 73.5 74.3 62.5 90.7 98.5 65.1 160.1 135.6 108.4 73.9 97.3 443.8 671.0 233.0 378.0 169.8 207.7 313.7 330.4 268.5 751.4 458.8 646.8 143.7 941.8 317.8 251.3 271.3 385.8 756.7 448.9 689.8 216.6 1300.5 433.9 312.4 762.2 269.9 535.6 331.0 231.4 404.1 414.6 593.1 181.1 390.0 548.2 526.1 234.4 296.1 308.6 766.4 385.6 525.9 497.2 396.7 601.2 329.1 515.0 440.5 328.7 186.0 348.0 271.4 344.4 483.6 232.1 218.1 267.1 231.1 240.1 219.7 275.9 729.9 122.0 201.2 415.0 229.3 506.2 376.8 68.1 197.6 49.9 217.1 212.0 283.5 330.1 239.0 215.4 389.5 289.8 289.7 245.7 15.5 240.7 166.4 325.4 203.6 432.6 85.5 85.7 91.5 118.3 89.5 94.3 89.6 92.3 93.2 93.1 90.7 97.3 101.6 28.9 30.5 10.7 153.1 243.1 229.0 283.3 165.0 70.5 157.3 209.4 84.8 102.9 107.8 82.8 27.1 323.8 115.0 105.6 313.1 248.0 75.1 106.7 149.9 108.2 79.2 183.1 10.8 205.1 457.9 101.0 94.8 85.9 62.2 131.6 75.3 128.5 202.7 60.6 11.6 190.2 154.6 85.3 129.8 89.5 119.6 101.8 156.5 10.3 170.3 105.2 93.7 11.1 16.1 199.3 128.5 98.6 197.4 255.1 78.9 444.1 65.1 79.9 85.5 101.6 189.1 79.3 237.3 284.4 255.3 179.0 105.5 354.3 364.0 253.8 C2orf72 LOC257407 ENSG00000204128 "Chromosome 2 open reading frame 72" A6NCS6 2 231037523-231049719 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 14.6;liver: 18.7" "Cell type enhanced" "Detected in many" "Astrocytes: 163.2;Cholangiocytes: 47.1;Hepatocytes: 129.1;Oligodendrocyte precursor cells: 45.8;Paneth cells: 51.3" "Cancer enhanced" "Detected in many" "liver cancer: 40.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.9;CACO-2: 2.2;EFO-21: 3.3;OE19: 4.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044962 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA044962: AB_10960863" "unprognostic (4.90e-2)" "unprognostic (7.03e-2)" "unprognostic (2.15e-1)" "unprognostic (7.44e-3)" "unprognostic (2.88e-2)" "unprognostic (6.41e-2)" "unprognostic (3.38e-1)" "unprognostic (6.51e-2)" "unprognostic (6.25e-3)" "unprognostic (1.84e-1)" "prognostic favorable (5.27e-4)" "unprognostic (2.65e-1)" "prognostic unfavorable (4.74e-4)" "unprognostic (2.78e-1)" "unprognostic (7.23e-3)" "unprognostic (2.70e-2)" "unprognostic (5.19e-2)" 0.0 0.0 6.7 0.0 8.2 0.0 0.3 4.3 8.8 0.0 0.0 3.0 0.6 0.0 0.1 0.0 0.0 0.4 0.0 8.7 6.2 0.2 18.7 0.1 0.0 8.4 12.1 0.0 1.4 0.2 1.1 0.9 6.0 0.5 0.7 0.0 0.1 0.0 0.0 0.1 1.1 0.0 5.8 0.0 1.5 0.1 14.6 0.0 0.0 0.0 0.0 0.0 0.0 6.1 0.0 0.5 0.4 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 2.2 0.0 0.0 3.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 4.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 1.5 0.1 1.0 0.5 0.5 0.6 0.0 0.0 0.0 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 8.2 4.3 8.8 8.7 6.2 8.4 12.1 6.0 5.8 14.6 6.1 0.0 0.0 0.0 163.2 0.5 0.1 0.1 0.0 0.0 1.9 5.9 6.0 0.5 47.1 0.0 0.0 0.0 1.8 0.2 32.8 1.9 3.9 13.6 0.1 0.2 0.2 4.9 10.7 33.4 2.0 11.9 0.2 4.6 0.1 0.0 0.1 3.6 129.1 0.6 0.0 15.0 14.8 0.0 2.9 0.0 30.8 0.3 0.2 1.8 6.5 0.0 15.7 0.0 45.8 20.1 0.8 51.3 4.1 0.2 0.7 10.7 1.8 0.0 0.3 0.0 0.0 0.1 0.5 0.9 0.0 0.0 5.2 0.3 0.0 28.8 0.3 C3orf14 HT021 ENSG00000114405 "Chromosome 3 open reading frame 14" Q9HBI5 3 62319015-62336213 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 159.7;Spermatocytes: 173.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 28.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 408.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048286 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 27: Brain & Skin - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Cytosol "HPA048286: AB_2680340" "unprognostic (8.00e-2)" "unprognostic (1.32e-1)" "unprognostic (7.81e-2)" "unprognostic (3.69e-3)" "unprognostic (6.91e-2)" "unprognostic (9.19e-2)" "unprognostic (5.76e-5)" "unprognostic (1.57e-3)" "unprognostic (2.67e-1)" "unprognostic (9.61e-2)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "prognostic favorable (4.33e-5)" "unprognostic (8.19e-2)" "unprognostic (1.73e-2)" "unprognostic (1.01e-1)" "unprognostic (1.59e-1)" 7.6 15.9 35.4 5.9 37.3 1.3 35.6 32.3 44.5 6.7 23.0 8.3 3.5 7.8 8.1 18.8 4.2 6.5 10.2 37.6 36.7 15.0 3.4 6.9 5.8 32.2 31.4 9.1 12.6 3.8 31.0 5.0 33.0 17.9 4.3 27.2 12.4 5.5 1.3 17.3 4.8 7.1 33.5 4.3 6.2 32.8 33.8 3.7 9.1 1.3 9.2 12.7 9.3 33.0 0.1 22.1 27.2 0.0 18.9 24.8 19.3 33.6 21.2 41.7 41.0 0.3 36.8 0.0 0.1 20.4 84.6 6.7 0.0 21.4 32.1 0.0 14.5 20.5 0.0 0.0 12.0 0.3 45.2 11.3 28.9 47.8 39.6 0.9 21.0 0.0 2.4 0.3 43.0 408.7 0.0 0.0 33.4 31.9 41.9 0.1 0.0 11.8 37.0 64.3 45.9 40.8 21.3 90.0 38.7 20.5 34.0 25.1 0.5 22.2 0.2 105.1 34.8 24.1 0.0 0.0 22.1 0.0 78.4 9.2 4.7 0.7 0.2 17.9 0.0 4.1 3.9 3.3 5.4 1.4 1.1 0.8 0.5 0.9 28.1 7.6 7.9 2.4 35.4 37.3 32.3 44.5 37.6 36.7 32.2 31.4 33.0 33.5 33.8 33.0 8.7 22.4 11.8 11.8 3.3 36.8 23.6 41.5 31.3 34.7 90.2 77.0 7.7 11.5 38.1 22.0 4.2 21.4 8.0 2.6 60.7 35.7 159.7 11.3 14.8 12.1 87.4 2.1 34.8 55.1 19.6 20.9 4.1 12.6 1.3 7.9 5.7 3.1 32.0 37.0 33.4 3.8 44.7 10.0 27.2 62.9 14.0 13.4 46.2 3.7 56.6 35.4 0.0 13.0 15.8 35.8 0.8 10.5 0.5 21.8 2.7 41.5 12.3 28.0 0.0 15.8 21.6 173.2 53.5 30.8 28.7 9.9 5.0 20.6 3.9 23.3 C3orf20 DKFZP434N1817 ENSG00000131379 "Chromosome 3 open reading frame 20" Q8ND61 3 14675141-14773036 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 15 "testis: 6.6" "Cell type enhanced" "Detected in some" "Astrocytes: 5.9;Early spermatids: 19.3;Excitatory neurons: 8.4;Inhibitory neurons: 6.9;Late spermatids: 34.6;Oligodendrocytes: 7.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "Daudi: 4.0;HEL: 8.2;U-698: 6.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA039584 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 36: HEL - Hemostasis" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA039584: AB_10795152" "unprognostic (1.23e-1)" "unprognostic (2.82e-1)" "unprognostic (5.88e-3)" "unprognostic (2.04e-1)" "unprognostic (3.51e-2)" "unprognostic (5.76e-3)" "unprognostic (1.81e-1)" "unprognostic (7.82e-2)" "unprognostic (1.63e-1)" "unprognostic (1.18e-1)" "unprognostic (9.08e-2)" "unprognostic (4.74e-2)" "unprognostic (3.24e-1)" "unprognostic (1.26e-1)" "unprognostic (1.97e-1)" "unprognostic (1.44e-1)" "unprognostic (1.39e-4)" 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 4.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 8.2 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.4 0.0 0.2 0.5 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.3 0.1 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.3 0.2 0.1 0.1 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 6.9 0.0 0.0 0.0 0.0 34.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 2.5 7.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 C8orf33 FLJ20989 ENSG00000182307 "Chromosome 8 open reading frame 33" Q9H7E9 8 145052465-145066685 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 180.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024812, HPA026104" Approved Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA024812: AB_10599490, HPA026104: AB_10600875" "prognostic unfavorable (2.77e-4)" "unprognostic (6.51e-3)" "unprognostic (1.85e-1)" "unprognostic (5.06e-2)" "unprognostic (1.12e-1)" "unprognostic (9.56e-3)" "prognostic unfavorable (8.95e-4)" "unprognostic (4.75e-2)" "unprognostic (3.51e-1)" "unprognostic (2.45e-2)" "unprognostic (5.17e-2)" "unprognostic (2.71e-1)" "unprognostic (1.05e-1)" "unprognostic (5.29e-2)" "unprognostic (1.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.37e-1)" 16.5 42.1 32.3 13.1 32.1 18.2 24.8 33.5 41.7 17.7 28.3 21.7 13.1 20.4 27.1 19.5 22.8 16.5 22.3 32.0 33.1 18.7 17.1 15.0 18.2 33.3 34.3 40.7 20.8 34.0 5.6 21.1 32.8 18.8 33.4 24.6 16.4 24.2 16.9 17.4 10.2 19.6 32.4 12.2 11.5 13.1 32.7 19.3 33.2 26.0 18.4 18.8 8.9 33.3 28.3 32.7 45.8 22.7 51.3 35.5 17.2 16.6 41.7 42.0 23.3 9.2 39.2 30.3 55.3 40.5 19.5 22.4 67.5 41.2 45.3 15.0 48.4 38.1 32.1 11.5 53.1 30.6 15.1 41.0 60.4 43.0 96.8 34.5 28.1 44.9 75.4 26.3 46.1 42.4 86.3 12.3 31.8 89.1 55.2 51.2 14.9 46.6 44.1 16.3 44.1 39.1 44.3 39.3 39.0 26.1 41.1 29.1 13.8 27.5 37.3 24.2 37.8 21.7 16.9 72.2 65.9 47.0 55.1 1.0 13.7 8.7 16.3 17.4 18.4 13.4 16.2 17.8 19.6 13.3 21.3 15.6 1.4 28.2 16.0 18.4 12.6 16.3 32.3 32.1 33.5 41.7 32.0 33.1 33.3 34.3 32.8 32.4 32.7 33.3 67.8 28.9 27.2 4.9 34.8 44.4 32.8 31.9 24.5 48.3 52.8 47.9 18.4 45.8 33.8 25.8 31.3 36.9 45.3 180.5 62.6 79.5 5.6 49.9 55.1 50.2 35.3 17.5 5.7 64.9 40.2 41.7 20.9 53.0 21.5 58.5 37.1 66.8 28.7 50.5 6.0 36.4 14.2 21.5 21.2 5.6 37.9 23.0 16.0 7.5 32.3 61.2 45.3 4.0 6.0 55.3 37.7 38.7 20.4 48.1 22.1 66.1 26.6 54.5 26.3 32.8 37.9 26.2 34.8 25.4 42.9 24.9 23.6 94.9 53.0 28.5 CACNA1I Cav3.3 ENSG00000100346 "Calcium voltage-gated channel subunit alpha1 I" Q9P0X4 22 39570753-39689735 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Calcium transport, Ion transport, Transport" "Calcium channel, Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 9.7;thyroid gland: 5.3" "Group enriched" "Detected in some" 4 "Bipolar cells: 16.9;Excitatory neurons: 16.8;Inhibitory neurons: 12.3" "Cancer enriched" "Detected in single" 5 "thyroid cancer: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "SK-BR-3: 1.9;T-47d: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA066992 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Cell Junctions" "HPA066992: " "unprognostic (3.97e-2)" "unprognostic (1.42e-1)" "unprognostic (1.02e-1)" "unprognostic (4.60e-2)" "unprognostic (3.52e-2)" "unprognostic (1.58e-1)" "unprognostic (1.19e-1)" "unprognostic (2.63e-1)" "unprognostic (7.21e-2)" "unprognostic (5.20e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.62e-2)" "unprognostic (6.14e-3)" "unprognostic (1.57e-1)" "unprognostic (3.78e-2)" "unprognostic (8.27e-4)" 0.2 3.3 5.0 0.8 5.6 0.6 0.1 1.5 9.7 0.1 0.0 0.5 0.1 0.1 0.0 0.2 0.2 0.1 0.0 8.7 1.3 0.1 0.0 0.5 1.9 7.6 1.4 0.0 0.1 0.0 0.3 0.0 7.9 0.1 0.0 2.6 0.1 0.0 0.0 0.2 3.3 0.0 0.7 1.5 0.6 0.8 2.2 0.2 5.3 0.0 0.5 0.4 0.2 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.1 1.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.1 0.0 5.0 5.6 1.5 9.7 8.7 1.3 7.6 1.4 7.9 0.7 2.2 4.7 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 16.9 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.2 0.0 0.1 0.0 0.4 16.8 0.0 0.0 0.1 0.5 0.2 0.0 0.0 0.0 0.0 0.0 3.3 12.3 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.0 1.0 2.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.1 0.1 CALD1 "CDM, H-CAD, L-CAD" ENSG00000122786 "Caldesmon 1" Q05682 7 134744252-134970729 "Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Muscle protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 916.1" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 1190.3;Leydig cells: 1745.0;Peritubular cells: 2005.6;Sertoli cells: 2294.3;Smooth muscle cells: 2549.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.9" "Lineage enriched" "Detected in single" 8 "granulocytes: 1.9" "Cell line enhanced" "Detected in many" "BJ hTERT+: 736.3;fHDF/TERT166: 1202.8;U-138 MG: 733.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000006, HPA008066, HPA017330" Enhanced Enhanced "Plasma membrane,Actin filaments" Yes No 39000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Actin filaments" "CAB000006: AB_2065456, HPA008066: AB_1078378, HPA017330: AB_1845917" "unprognostic (2.16e-2)" "unprognostic (1.19e-2)" "unprognostic (2.80e-3)" "unprognostic (3.05e-2)" "unprognostic (4.51e-2)" "unprognostic (1.51e-1)" "unprognostic (2.58e-1)" "unprognostic (1.22e-2)" "prognostic unfavorable (3.73e-4)" "unprognostic (2.07e-1)" "unprognostic (1.27e-1)" "unprognostic (1.14e-1)" "prognostic unfavorable (1.84e-5)" "unprognostic (6.52e-3)" "unprognostic (1.14e-2)" "unprognostic (1.19e-1)" "unprognostic (1.18e-3)" 225.8 119.2 27.3 164.9 35.0 1.3 161.1 28.1 47.6 241.6 37.2 916.1 80.3 523.3 150.7 275.6 304.4 203.2 115.0 26.9 29.1 134.7 224.4 155.5 75.4 32.3 30.4 326.2 52.5 32.7 53.3 430.0 30.9 348.9 149.8 13.1 70.3 781.7 46.5 76.0 233.1 688.4 27.9 129.2 324.2 52.7 33.4 28.5 114.1 75.2 34.4 505.3 208.0 28.8 115.9 75.3 163.3 146.1 572.7 464.8 161.6 661.6 736.3 227.2 246.6 138.3 3.5 0.7 153.3 1202.8 148.1 26.9 106.0 202.3 308.4 1.5 38.9 4.0 87.8 94.7 375.6 1.5 0.8 360.9 153.6 252.8 147.4 343.6 193.0 0.0 0.6 1.6 338.7 0.3 0.6 3.2 197.7 0.1 25.6 1.4 146.6 2.3 46.9 32.2 29.0 72.1 235.3 31.7 90.0 491.0 7.2 1.4 508.5 733.2 130.0 143.8 230.3 0.9 1.1 1.3 259.0 0.8 573.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.9 0.2 0.0 0.0 0.0 2.9 27.3 35.0 28.1 47.6 26.9 29.1 32.3 30.4 30.9 27.9 33.4 28.8 400.6 22.4 17.6 43.1 7.3 420.4 379.6 218.8 164.4 172.0 115.5 466.1 456.5 228.8 33.5 44.1 6.2 202.7 5.0 0.3 23.5 392.6 61.0 89.4 1190.3 432.9 3.6 16.0 95.4 23.6 903.9 886.9 16.3 206.2 5.1 251.0 422.0 638.4 43.5 92.5 58.3 1.2 28.5 21.0 112.8 83.6 1745.0 38.8 336.2 94.6 8.4 140.6 6.2 98.5 158.8 146.0 0.2 2005.6 4.2 456.9 0.1 332.1 11.3 21.2 2294.3 326.1 2549.3 12.1 12.2 70.1 171.8 276.6 27.5 414.1 0.8 36.7 CALML5 CLSP ENSG00000178372 "Calmodulin like 5" Q9NZT1 10 5498697-5499570 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "skin 1: 3060.6" "Group enriched" "Detected in some" 4 "Breast glandular cells: 172.1;Breast myoepithelial cells: 156.1;Suprabasal keratinocytes: 390.7" "Group enriched" "Detected in many" 6 "breast cancer: 97.6;cervical cancer: 189.1;head and neck cancer: 206.0;melanoma: 222.1;urothelial cancer: 82.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 21 "A-431: 400.3" "Not detected" "Not detected" HPA040725 Enhanced Approved "Plasma membrane,Cytosol" NA NA 48000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA040725: AB_10793863" "unprognostic (7.68e-3)" "unprognostic (5.06e-3)" "unprognostic (5.64e-2)" "prognostic favorable (2.59e-5)" "unprognostic (4.82e-2)" "unprognostic (2.67e-1)" "unprognostic (1.37e-1)" "unprognostic (8.27e-2)" "unprognostic (1.14e-1)" "unprognostic (2.79e-1)" "unprognostic (1.71e-1)" "unprognostic (4.99e-2)" 3.9 0.5 0.0 0.0 0.0 0.1 41.2 0.0 0.0 94.0 0.0 0.8 0.0 0.3 0.7 67.5 0.1 0.0 1.3 0.0 0.0 0.3 1.7 0.8 0.0 0.0 0.0 0.4 1.1 0.0 0.5 0.0 0.0 0.5 0.0 0.0 554.0 0.0 11.7 3060.6 0.6 0.0 0.0 0.4 0.8 1.0 0.0 9.2 0.6 0.0 13.4 0.1 306.6 0.0 400.3 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 7.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 18.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.5 0.6 0.0 0.0 1.2 0.4 0.0 0.0 0.0 0.8 0.0 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.4 27.3 0.3 2.2 0.0 0.0 172.1 156.1 0.2 0.0 1.8 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 0.0 11.1 0.0 0.0 0.4 56.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.5 0.0 0.0 0.0 1.3 0.2 0.3 6.8 390.7 0.0 1.2 0.0 0.0 3.3 CALN1 CABP8 ENSG00000183166 "Calneuron 1" Q9BXU9 7 71779491-72447151 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "adrenal gland: 11.3;brain: 44.3;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "Astrocytes: 88.8;Excitatory neurons: 130.6;Inhibitory neurons: 212.7;Oligodendrocyte precursor cells: 44.7" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 6 "Karpas-707: 44.5" "Low region specificity" "Detected in all" "HPA036278, HPA036708" Approved Uncertain "Vesicles,Plasma membrane" No No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Vesicles "Plasma membrane" "HPA036278: AB_10673125, HPA036708: " "unprognostic (6.38e-2)" "unprognostic (1.11e-1)" "unprognostic (2.87e-1)" "unprognostic (1.32e-2)" "unprognostic (2.02e-1)" "unprognostic (1.13e-2)" "unprognostic (3.67e-4)" "unprognostic (3.16e-1)" "unprognostic (1.29e-1)" "unprognostic (1.57e-2)" "unprognostic (1.41e-1)" "unprognostic (2.43e-1)" "unprognostic (1.83e-2)" "unprognostic (3.53e-2)" "unprognostic (1.23e-2)" "unprognostic (7.72e-4)" "unprognostic (2.99e-1)" 0.1 11.3 12.2 0.0 18.5 0.6 0.2 44.3 15.0 1.5 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 25.4 40.6 0.0 0.2 0.0 0.0 27.9 17.0 0.1 1.0 0.0 0.5 0.0 30.2 0.2 0.1 1.9 0.0 1.1 0.0 3.5 0.0 0.0 15.2 0.0 0.0 3.2 8.3 24.7 0.1 0.0 0.0 0.0 3.2 26.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 44.5 0.0 0.0 0.1 0.0 6.0 0.0 0.0 7.1 0.0 0.8 0.0 0.0 6.7 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 7.2 0.1 0.0 7.0 7.3 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.2 18.5 44.3 15.0 25.4 40.6 27.9 17.0 30.2 15.2 8.3 26.5 0.0 0.0 0.0 88.8 0.0 2.3 0.4 0.0 0.0 3.8 0.0 0.6 5.6 5.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 6.8 0.1 0.1 0.3 0.0 2.1 130.6 0.0 0.0 0.2 0.0 0.4 0.0 0.0 1.4 0.4 0.1 0.0 212.7 1.5 0.0 0.3 0.7 7.0 0.0 0.1 0.0 14.0 0.0 0.2 1.0 44.7 15.7 0.0 0.1 0.7 0.0 0.2 0.0 0.1 0.0 0.8 0.0 6.1 0.2 8.8 12.8 0.0 9.8 0.1 0.2 0.2 0.1 0.1 CASP4 "ICE(rel)II, ICH-2, TX" ENSG00000196954 "Caspase 4" P49662 11 104942866-104969366 "Cancer-related genes, Enzymes, Predicted intracellular proteins" "Immunity, Inflammatory response, Innate immunity, Necrosis" "Hydrolase, Protease, Thiol protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "HPA027588, CAB037167" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB037167: AB_258864, HPA027588: AB_10603781" "unprognostic (1.19e-2)" "unprognostic (3.73e-1)" "unprognostic (3.44e-1)" "unprognostic (1.99e-2)" "unprognostic (7.19e-3)" "unprognostic (2.63e-2)" "unprognostic (1.26e-2)" "unprognostic (1.56e-2)" "unprognostic (5.31e-2)" "unprognostic (2.71e-1)" "unprognostic (2.38e-3)" "unprognostic (8.39e-3)" "prognostic unfavorable (3.27e-11)" "unprognostic (6.75e-2)" "unprognostic (1.34e-1)" "unprognostic (1.79e-2)" "unprognostic (4.08e-3)" 45.7 21.7 7.0 69.4 7.2 48.5 44.4 7.4 12.4 26.4 8.6 27.6 62.4 18.4 33.1 47.7 34.9 50.1 17.8 7.5 8.0 33.3 54.1 61.3 80.2 9.7 8.1 43.2 52.5 4.7 11.0 70.2 8.7 21.7 30.7 2.0 55.2 15.5 7.5 46.7 58.8 32.2 8.3 71.1 42.4 4.9 9.0 57.2 15.6 18.1 82.1 76.5 30.5 8.7 33.8 9.5 0.0 12.9 58.2 140.4 27.8 68.0 103.2 80.5 117.0 22.4 128.5 22.3 123.1 71.5 110.4 52.7 0.0 94.3 78.8 22.4 0.4 53.1 7.4 55.8 158.2 48.5 19.2 122.6 127.0 97.9 144.4 104.7 143.8 0.5 1.3 0.0 64.4 2.8 26.1 46.7 0.0 71.6 28.2 21.4 21.5 14.2 64.9 46.2 0.6 0.4 60.8 31.6 49.3 0.7 11.9 62.5 93.2 84.4 30.4 80.8 40.5 0.0 0.0 0.3 42.2 105.5 63.4 136.4 292.0 50.6 208.9 312.9 224.8 141.9 155.6 193.9 205.5 144.4 93.4 138.5 667.2 226.2 255.4 35.4 257.9 410.9 7.0 7.2 7.4 12.4 7.5 8.0 9.7 8.1 8.7 8.3 9.0 8.7 78.1 60.9 60.8 0.3 87.4 55.8 63.3 130.1 21.1 0.0 40.8 48.4 5.6 47.1 107.0 22.0 0.0 129.1 80.4 12.4 15.6 157.5 0.6 35.9 27.7 73.0 20.9 12.4 0.0 189.9 103.0 53.6 33.1 45.7 34.8 32.6 82.1 34.7 116.7 0.0 0.2 37.8 73.2 168.0 81.2 2.1 29.2 105.2 30.2 23.4 141.5 1.9 177.1 1.5 0.2 148.5 8.6 20.7 50.5 31.1 85.4 41.1 86.1 0.4 6.6 38.1 34.2 0.2 0.5 25.8 45.9 115.9 102.1 36.8 32.9 80.0 CAV3 "LGMD1C, LQT9, VIP-21, VIP21" ENSG00000182533 "Caveolin 3" P56539 3 8733802-8841808 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Cardiomyopathy, Disease variant, Limb-girdle muscular dystrophy, Long QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "skeletal muscle: 182.7;tongue: 72.8" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 22.9;Early spermatids: 4.2;Sertoli cells: 6.6;Skeletal myocytes: 11.0" "Cancer enhanced" "Detected in single" "head and neck cancer: 0.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "RH-30: 94.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017518, CAB018557, HPA054488" Enhanced Approved "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Vesicles "CAB017518: AB_628860, CAB018557: AB_626814, HPA054488: AB_2682504" "unprognostic (1.79e-1)" "unprognostic (1.43e-1)" "unprognostic (1.40e-2)" "unprognostic (6.43e-2)" "unprognostic (8.79e-2)" "unprognostic (3.05e-3)" "unprognostic (8.38e-3)" "unprognostic (9.79e-2)" "unprognostic (1.36e-1)" 0.4 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.2 5.7 0.1 0.1 27.4 0.1 0.1 0.0 0.0 0.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.1 0.0 2.5 0.2 182.7 0.2 0.1 0.0 0.0 0.1 0.1 0.4 0.1 0.2 0.1 72.8 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 94.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 2.5 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 11.0 2.3 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 CAVIN1 "cavin-1, CGL4, PTRF" ENSG00000177469 "Caveolae associated protein 1" Q6NZI2 17 42402449-42423256 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Transcription, Transcription regulation, Transcription termination" "RNA-binding, rRNA-binding" "Congenital generalized lipodystrophy, Diabetes mellitus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 575.1;Alveolar cells type 1: 429.5;Breast myoepithelial cells: 154.9;Cytotrophoblasts: 159.8;Endothelial cells: 217.4;Smooth muscle cells: 211.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 1105.9;fHDF/TERT166: 796.6;TIME: 920.9;U-138 MG: 912.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049838, HPA074213" Supported Supported "Vesicles,Plasma membrane" NA NA 440000 "Cluster 11: Basophils - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Vesicles "HPA049838: AB_2680907, HPA074213: AB_2686674" "unprognostic (1.59e-1)" "unprognostic (4.46e-2)" "prognostic unfavorable (6.36e-4)" "unprognostic (1.56e-1)" "unprognostic (1.76e-3)" "unprognostic (6.33e-3)" "unprognostic (1.72e-1)" "unprognostic (1.04e-1)" "unprognostic (1.43e-1)" "prognostic unfavorable (5.92e-4)" "unprognostic (7.18e-3)" "unprognostic (2.36e-1)" "unprognostic (3.44e-3)" "unprognostic (4.24e-3)" "unprognostic (3.21e-2)" "unprognostic (2.07e-3)" "prognostic unfavorable (5.87e-4)" 397.8 65.3 42.6 69.1 47.2 3.7 295.3 55.8 40.9 239.9 50.6 314.0 30.8 344.3 56.8 101.0 207.5 78.1 220.9 35.4 49.7 66.4 21.0 202.8 30.0 68.8 55.0 162.5 28.4 26.5 34.8 151.3 60.1 181.5 50.7 3.6 84.2 215.4 144.8 161.9 104.1 242.3 53.5 109.0 132.8 22.6 47.2 16.6 112.4 92.7 24.0 255.4 192.3 58.0 315.9 264.8 5.5 69.8 342.3 409.6 6.9 1105.9 477.8 432.2 340.5 134.6 20.1 0.5 216.3 796.6 177.4 509.7 46.8 331.6 351.0 1.1 9.5 137.5 154.8 66.1 215.8 0.3 1.2 283.0 120.5 340.8 115.8 230.2 592.3 0.4 95.5 1.3 187.9 5.0 7.4 1.6 25.8 48.1 1.8 0.6 173.3 0.6 186.1 1.6 0.4 2.0 371.9 6.4 91.7 145.2 29.8 2.0 920.9 912.0 429.5 330.9 407.9 0.8 0.9 1.6 270.7 0.5 104.8 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 42.6 47.2 55.8 40.9 35.4 49.7 68.8 55.0 60.1 53.5 47.2 58.0 575.1 429.5 117.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 55.4 154.9 0.0 0.0 50.8 23.9 0.0 159.8 3.4 0.0 3.9 45.6 0.0 11.7 130.4 217.4 0.0 0.0 0.0 4.4 11.3 114.2 0.0 16.9 63.1 116.3 0.0 0.0 16.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 108.5 0.0 0.0 0.5 0.0 0.0 1.1 3.6 0.0 0.0 0.0 211.7 0.0 0.0 0.0 0.0 77.2 4.5 6.6 0.0 0.0 CAVIN2 "cavin-2, PS-p68, SDPR, SDR" ENSG00000168497 "Caveolae associated protein 2" O95810 2 191834310-191847088 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Adipocytes: 1296.7;Alveolar cells type 1: 413.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 12 "basophil: 49.0;neutrophil: 24.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 49.0" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 162.3;HEL: 119.8;HUVEC TERT2: 362.3;LHCN-M2: 561.1;TIME: 148.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039325, HPA062122" Enhanced Enhanced "Plasma membrane,Cytosol" Yes No 88000000 "Cluster 34: Basophils - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA039325: AB_10805473, HPA062122: AB_2684688" "unprognostic (6.85e-3)" "unprognostic (1.37e-1)" "unprognostic (1.24e-1)" "unprognostic (4.47e-2)" "unprognostic (2.83e-1)" "unprognostic (1.46e-1)" "unprognostic (3.19e-2)" "unprognostic (6.14e-2)" "unprognostic (8.50e-2)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (2.90e-1)" "prognostic favorable (8.45e-5)" "prognostic unfavorable (3.69e-4)" "unprognostic (1.03e-1)" "unprognostic (1.33e-1)" "unprognostic (4.39e-3)" 164.9 25.1 17.9 13.0 20.1 6.5 60.9 16.9 20.2 56.8 13.1 69.4 11.5 38.9 13.2 48.2 53.9 51.8 96.7 15.1 16.5 25.9 31.2 93.9 15.3 19.5 17.3 53.0 22.5 12.9 7.1 34.0 19.5 30.2 24.9 1.1 7.1 30.0 32.3 6.9 21.1 58.1 15.9 111.9 15.0 4.3 22.3 4.1 78.3 59.9 5.6 42.7 19.5 17.0 0.0 20.2 6.8 0.1 1.0 3.4 0.1 4.1 3.5 0.8 1.5 0.0 0.0 0.1 24.8 162.3 0.0 3.4 0.0 31.8 2.3 0.1 0.0 119.8 1.4 45.6 43.6 0.0 0.0 8.4 20.5 3.4 9.6 2.2 362.3 0.0 43.9 0.0 561.1 0.0 0.0 0.1 0.1 0.0 1.0 0.0 32.3 0.2 41.7 0.0 0.0 0.1 0.0 0.0 0.0 9.1 0.0 0.1 148.9 0.0 12.4 7.4 0.0 0.0 0.0 0.1 0.0 1.0 0.0 49.0 2.4 1.2 0.2 0.8 0.3 0.1 0.0 0.0 2.3 0.3 0.2 0.0 24.3 1.3 1.5 3.1 0.5 121.3 17.9 20.1 16.9 20.2 15.1 16.5 19.5 17.3 19.5 15.9 22.3 17.0 1296.7 413.5 76.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 1.7 15.6 0.0 0.0 81.7 0.0 0.0 0.2 2.6 0.0 5.9 1.6 0.0 0.4 5.4 164.5 0.0 0.0 0.0 0.2 0.2 15.0 0.0 0.6 185.4 0.1 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.7 29.2 0.0 0.0 0.0 11.8 0.0 0.0 0.0 0.0 0.1 1.5 16.4 0.0 0.0 CBY2 "NURIT, SPERT" ENSG00000174015 "Chibby family member 2" Q8NA61 13 45702320-45714559 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 441 "testis: 99.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in single" "urothelial cancer: 0.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039359, HPA040046" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 36: Testis - Spermatogenesis" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cell Junctions" "HPA039359: AB_10794088, HPA040046: AB_10796117" "unprognostic (2.86e-1)" "unprognostic (3.38e-1)" "unprognostic (1.64e-2)" "unprognostic (1.65e-1)" "unprognostic (3.76e-2)" "unprognostic (4.19e-4)" "unprognostic (8.52e-2)" "unprognostic (8.87e-2)" "unprognostic (1.23e-1)" "unprognostic (4.38e-1)" "unprognostic (2.38e-2)" "unprognostic (1.21e-1)" "unprognostic (1.56e-2)" "unprognostic (1.97e-2)" "unprognostic (4.15e-3)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 99.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CCBE1 "FLJ30681, KIAA1983" ENSG00000183287 "Collagen and calcium binding EGF domains 1" Q6UXH8 18 59430939-59697662 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" Angiogenesis "Developmental protein" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 33.5" "Cell type enhanced" "Detected in many" "Excitatory neurons: 56.1;Rod photoreceptor cells: 38.2;Theca cells: 78.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 6 "basophil: 9.2" "Lineage enriched" "Detected in single" 19 "granulocytes: 9.2" "Cell line enhanced" "Detected in many" "BJ: 101.2;BJ hTERT+: 103.2;BJ hTERT+ SV40 Large T+ RasG12V: 96.4;HBF TERT88: 113.3;hTERT-HME1: 153.2;LHCN-M2: 176.9;TIME: 93.3" "Group enriched" "Detected in many" 5 "cerebral cortex: 2.7;hippocampal formation: 8.7" "Low region specificity" "Detected in many" "HPA041361, HPA041374" Uncertain Supported "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA041361: AB_10796667, HPA041374: AB_10794515" "unprognostic (3.09e-1)" "unprognostic (5.01e-2)" "unprognostic (9.54e-5)" "unprognostic (1.66e-2)" "unprognostic (2.40e-2)" "unprognostic (5.68e-5)" "unprognostic (2.31e-2)" "unprognostic (2.03e-1)" "unprognostic (4.54e-2)" "unprognostic (1.21e-1)" "unprognostic (7.39e-2)" "unprognostic (2.17e-2)" "unprognostic (3.62e-3)" "unprognostic (4.04e-3)" "unprognostic (1.64e-1)" "unprognostic (7.45e-2)" "unprognostic (2.02e-2)" 4.1 10.2 2.7 1.2 3.4 0.5 1.8 2.2 3.0 10.5 0.7 16.7 1.1 6.9 0.5 2.8 8.3 1.3 2.1 6.5 1.1 3.3 5.7 9.9 1.3 0.2 1.9 33.5 1.1 2.9 0.4 0.5 0.3 2.4 2.8 1.1 0.6 4.0 15.3 3.0 2.5 3.2 0.2 0.5 1.6 0.6 3.7 1.2 0.9 0.9 0.7 0.8 1.3 1.5 20.6 1.9 0.0 0.2 15.1 47.2 30.7 101.2 103.2 73.5 96.4 0.3 0.3 0.4 0.2 40.6 16.7 2.3 0.2 65.5 113.3 0.4 0.3 0.2 0.4 0.3 35.1 0.3 0.2 32.0 2.9 57.0 153.2 31.2 3.6 0.3 0.2 0.5 176.9 0.6 0.1 0.2 0.3 0.0 0.6 0.1 0.2 0.2 3.9 2.0 0.4 0.7 0.3 0.2 0.9 7.2 0.3 0.5 93.3 0.2 10.0 15.3 0.3 0.3 0.3 0.2 5.0 0.3 2.4 9.2 0.2 0.5 0.1 0.1 0.1 0.2 0.1 0.1 0.0 0.4 0.2 0.2 1.5 0.4 0.1 0.2 0.1 0.1 2.7 3.4 2.2 3.0 6.5 1.1 0.2 1.9 0.3 0.2 3.7 1.5 1.5 3.2 1.3 3.9 0.2 4.6 2.0 1.0 2.2 6.4 0.8 0.4 1.6 2.8 1.9 0.0 8.4 1.0 0.2 0.2 0.0 0.2 0.8 8.8 5.1 2.2 0.0 0.0 56.1 0.2 1.3 14.5 0.0 0.6 1.3 6.8 9.7 0.2 0.4 15.2 15.1 0.0 0.0 1.0 8.9 1.1 9.6 0.5 7.2 1.0 0.2 2.4 0.0 0.5 0.7 0.3 0.0 0.4 0.1 1.5 0.1 0.1 0.9 38.2 0.0 1.6 5.9 0.4 0.9 0.2 4.3 0.8 1.2 78.0 0.1 0.9 CCDC115 "ccp1, FLJ30131, MGC12981" ENSG00000136710 "Coiled-coil domain containing 115" Q96NT0 2 130337933-130342699 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA034598 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Vesicles "HPA034598: AB_10601697" "prognostic favorable (7.59e-4)" "unprognostic (1.28e-2)" "unprognostic (1.10e-3)" "unprognostic (6.80e-3)" "unprognostic (3.23e-1)" "unprognostic (1.08e-1)" "unprognostic (4.20e-2)" "unprognostic (8.13e-3)" "unprognostic (2.63e-1)" "unprognostic (4.29e-1)" "unprognostic (2.87e-1)" "unprognostic (1.91e-2)" "unprognostic (1.19e-2)" "unprognostic (1.07e-1)" "unprognostic (7.83e-2)" "unprognostic (2.16e-1)" "unprognostic (3.16e-2)" 27.8 25.1 25.3 18.0 25.8 24.8 25.4 26.4 28.0 33.7 21.7 25.3 21.2 29.5 32.3 31.1 29.9 19.9 18.4 25.2 26.6 29.8 17.8 26.6 29.8 26.8 25.3 41.6 20.2 40.2 22.9 13.8 26.3 24.0 19.3 15.8 29.1 27.7 12.9 39.3 24.2 17.7 26.1 26.1 24.1 10.4 25.4 23.3 30.3 12.3 26.0 26.8 28.1 27.5 22.5 10.5 13.3 8.1 27.2 30.7 16.3 10.5 28.2 22.4 26.1 24.4 48.5 25.7 36.6 18.3 11.4 20.7 10.8 19.2 16.1 33.4 20.2 20.2 5.4 27.3 22.7 20.8 40.2 26.2 44.2 14.6 8.1 21.8 23.7 24.3 19.8 22.6 27.7 20.7 38.5 37.5 17.2 11.2 26.4 29.4 14.2 24.1 18.8 18.6 12.4 22.8 12.3 22.4 24.2 8.7 24.5 25.3 18.6 10.1 10.4 18.5 8.3 12.4 13.0 19.7 22.9 22.1 13.5 129.9 94.6 154.8 80.8 136.0 71.8 96.3 85.1 85.8 95.2 98.9 81.1 74.8 33.3 80.6 174.9 73.8 103.6 132.8 25.3 25.8 26.4 28.0 25.2 26.6 26.8 25.3 26.3 26.1 25.4 27.5 37.5 19.2 28.3 3.6 43.6 51.9 42.3 104.2 40.5 25.9 43.3 41.9 13.9 35.8 50.8 77.3 10.4 76.7 35.1 29.9 105.7 47.4 1.4 14.5 16.9 30.8 27.6 13.5 8.7 42.7 36.6 30.6 21.4 20.3 53.3 22.7 33.2 21.4 63.5 23.5 12.3 35.6 99.7 45.5 60.7 4.5 42.6 49.4 53.4 5.6 97.3 48.4 49.4 10.1 12.2 27.5 49.1 52.3 16.9 14.9 51.9 65.9 24.3 27.6 46.0 29.2 31.7 9.0 24.0 42.4 70.0 26.4 51.3 39.1 41.6 30.0 CCDC124 ENSG00000007080 "Coiled-coil domain containing 124" Q96CT7 19 17933015-17943991 "Predicted intracellular proteins" "Cell cycle, Cell division" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041708, HPA046765" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA041708: AB_2677628, HPA046765: AB_2679793" "unprognostic (9.39e-2)" "unprognostic (1.36e-1)" "unprognostic (2.51e-1)" "unprognostic (1.70e-1)" "unprognostic (2.16e-1)" "unprognostic (1.97e-1)" "prognostic unfavorable (1.68e-4)" "unprognostic (4.32e-2)" "unprognostic (1.02e-1)" "unprognostic (3.20e-2)" "unprognostic (1.34e-1)" "unprognostic (2.04e-2)" "unprognostic (1.10e-1)" "unprognostic (2.50e-1)" "unprognostic (2.19e-1)" "unprognostic (3.71e-2)" "unprognostic (3.22e-1)" 82.9 67.6 62.4 32.0 62.9 42.7 78.0 64.1 104.5 77.3 54.0 115.7 25.6 78.6 7.1 100.3 67.8 11.2 131.9 61.9 60.7 88.5 88.0 70.8 22.7 63.2 62.1 64.9 72.2 22.1 55.7 20.3 64.8 77.9 8.4 9.0 69.3 22.2 210.2 92.8 58.5 14.2 57.3 67.5 81.2 48.5 66.0 17.7 65.6 38.3 12.2 84.5 80.9 68.2 242.7 165.3 54.2 111.3 35.4 26.9 178.8 118.9 36.7 59.0 49.8 125.0 97.1 182.8 166.7 47.5 38.8 90.1 60.0 108.3 17.2 194.7 341.8 152.7 140.5 147.0 68.4 174.4 100.6 43.2 70.7 59.7 56.9 33.9 62.7 115.0 196.3 74.4 30.8 232.8 166.1 212.3 126.3 79.2 282.2 163.2 103.6 195.1 48.9 85.7 108.6 155.8 83.4 92.4 121.3 22.0 86.2 62.6 142.0 102.3 128.1 198.0 185.6 102.8 121.7 178.5 128.6 203.1 133.0 81.1 82.2 73.5 85.9 95.1 69.2 61.0 66.8 80.8 85.5 66.4 51.8 63.5 20.5 76.3 71.3 75.4 84.1 66.2 62.4 62.9 64.1 104.5 61.9 60.7 63.2 62.1 64.8 57.3 66.0 68.2 58.8 19.2 4.8 8.1 41.1 90.5 60.0 115.9 44.9 22.9 49.3 57.3 15.6 35.8 58.7 73.5 2.1 93.8 44.1 108.9 137.0 146.2 33.4 46.7 50.9 57.3 61.0 79.8 7.4 199.0 140.2 58.1 79.0 56.5 27.3 73.9 50.7 57.1 110.3 10.1 6.4 89.0 101.7 60.0 73.2 106.1 32.6 50.3 96.0 4.7 86.4 50.9 50.4 4.5 7.1 227.9 70.0 41.3 68.7 108.7 78.5 142.3 44.8 23.1 19.7 43.4 76.0 30.9 39.9 79.6 109.8 82.8 42.8 184.7 88.6 73.5 CCDC15 FLJ13215 ENSG00000149548 "Coiled-coil domain containing 15" Q0P6D6 11 124954121-125041489 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 10.5" "Group enriched" "Detected in many" 5 "Early spermatids: 42.8;Erythroid cells: 26.3;Late spermatids: 25.8;Spermatocytes: 99.7;Spermatogonia: 34.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040450, HPA041738" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Cytosol "HPA040450: AB_10794031, HPA041738: AB_10794675" "unprognostic (2.38e-1)" "unprognostic (3.93e-2)" "unprognostic (8.81e-2)" "unprognostic (1.85e-1)" "unprognostic (2.50e-1)" "unprognostic (4.59e-4)" "unprognostic (2.12e-3)" "unprognostic (1.43e-1)" "unprognostic (1.46e-2)" "unprognostic (2.04e-2)" "unprognostic (9.05e-3)" "unprognostic (3.25e-2)" "unprognostic (9.38e-3)" "unprognostic (1.33e-2)" "unprognostic (3.14e-1)" "unprognostic (5.04e-2)" "unprognostic (1.66e-1)" 0.7 0.3 0.5 0.9 0.8 2.1 2.8 0.5 0.6 0.6 0.3 0.8 0.7 0.6 1.5 0.8 1.1 0.5 0.2 0.6 0.5 0.6 1.3 0.7 1.2 0.9 0.6 0.8 0.8 0.6 0.5 0.7 0.6 1.6 0.8 1.7 3.9 0.5 0.1 2.1 0.7 0.6 0.7 0.8 0.6 10.5 0.7 2.8 0.7 0.2 1.4 0.5 0.6 1.2 5.4 1.0 6.9 0.0 0.5 1.9 0.0 5.7 6.9 5.3 6.5 0.1 4.4 6.3 4.9 2.0 10.5 4.2 2.9 3.8 9.4 5.3 1.1 7.7 0.8 1.6 0.2 2.3 4.3 0.5 2.7 11.0 5.5 1.0 4.0 7.8 5.2 6.3 11.2 1.2 4.9 2.6 1.6 4.6 6.3 5.9 12.6 2.0 0.8 2.1 3.9 3.4 3.3 0.4 1.5 3.3 7.9 2.0 2.9 10.8 2.4 4.8 7.2 1.5 1.8 5.3 1.5 12.6 7.3 4.0 0.5 0.8 1.0 0.7 1.1 0.3 0.9 1.7 0.1 0.7 1.2 1.4 0.4 1.1 0.8 0.5 1.7 0.5 0.5 0.8 0.5 0.6 0.6 0.5 0.9 0.6 0.6 0.7 0.7 1.2 2.4 3.2 1.1 5.2 2.3 5.0 2.1 2.2 2.2 6.4 4.2 2.8 0.6 0.0 2.9 0.0 0.0 0.9 2.9 1.1 0.0 2.3 42.8 2.6 2.0 3.4 1.2 26.3 1.2 3.5 0.4 2.5 3.6 1.4 8.9 4.4 1.4 1.4 3.2 3.3 2.0 2.1 0.0 2.6 3.3 25.8 4.4 2.6 3.6 1.0 0.7 3.6 8.2 5.0 6.1 1.8 0.5 2.2 1.2 1.1 0.2 1.0 5.3 2.8 6.6 2.2 2.3 99.7 34.5 3.2 3.8 0.1 3.4 0.9 1.7 1.2 CCDC154 "C16orf29, LOC645811" ENSG00000197599 "Coiled-coil domain containing 154" 16 1434383-1444556 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "testis: 11.6" "Cell type enriched" "Detected in some" 4 "Early spermatids: 51.6" "Cancer enhanced" "Detected in many" "prostate cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 9.5;NB-4: 4.7;SCLC-21H: 33.2;U-266/70: 5.8" "Not detected" "Not detected" "Region enhanced" "Detected in single" "cerebellum: 1.9" "HPA041158, HPA043535, HPA048237" Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 43: Testis - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "Golgi apparatus" "HPA041158: , HPA043535: AB_2678536, HPA048237: AB_2680323" "unprognostic (2.40e-1)" "unprognostic (1.42e-2)" "unprognostic (5.97e-4)" "unprognostic (3.28e-2)" "unprognostic (1.97e-1)" "unprognostic (5.76e-3)" "unprognostic (7.96e-2)" "unprognostic (3.01e-3)" "unprognostic (1.67e-1)" "unprognostic (5.34e-2)" "unprognostic (4.19e-5)" "unprognostic (2.35e-2)" "unprognostic (8.02e-6)" "unprognostic (9.33e-2)" "unprognostic (1.43e-1)" "unprognostic (2.33e-1)" "unprognostic (9.35e-5)" 0.6 0.8 1.5 0.9 1.7 1.0 0.8 1.7 2.2 1.9 0.5 1.2 1.4 1.0 0.3 0.4 1.9 0.5 0.7 1.4 1.3 2.3 0.7 0.8 1.4 1.8 1.4 1.5 1.2 0.1 3.8 0.4 1.6 1.5 0.1 0.8 0.7 0.4 0.8 1.5 1.2 0.2 0.9 2.2 2.0 11.6 1.5 0.4 2.8 0.1 0.4 0.8 0.9 2.4 9.5 0.4 0.3 0.6 0.4 0.2 0.4 0.1 0.0 0.0 0.0 0.3 0.8 0.1 0.3 0.0 0.4 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.3 0.4 0.3 0.1 0.5 0.1 0.3 0.1 0.0 0.1 0.0 0.1 1.2 0.5 0.0 0.7 0.0 4.7 0.2 0.0 0.1 2.8 0.1 0.2 0.0 0.2 33.2 0.5 0.1 0.2 1.4 0.1 1.0 2.4 0.0 0.4 0.1 0.4 0.0 5.8 1.6 0.1 0.0 4.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.7 1.7 2.2 1.4 1.3 1.8 1.4 1.6 0.9 1.5 2.4 0.2 0.0 0.0 9.8 1.4 0.0 0.5 0.2 0.0 3.2 0.5 0.6 0.6 1.5 0.1 3.7 8.4 0.0 0.4 0.1 0.0 0.1 51.6 0.3 0.3 0.1 0.0 0.0 3.9 0.4 0.0 0.3 1.1 0.3 1.3 1.5 0.4 0.2 0.8 6.7 4.8 0.5 0.0 0.3 0.8 11.1 1.5 0.6 1.8 7.5 0.8 2.4 0.0 2.0 3.8 0.0 0.0 0.4 0.0 0.1 0.2 0.2 0.8 4.2 0.0 0.3 0.6 10.1 1.2 0.0 0.4 0.0 0.7 0.4 0.0 0.2 CCDC28A "C6orf80, CCRL1AP, DKFZp586D0623" ENSG00000024862 "Coiled-coil domain containing 28A" 6 138773769-138793319 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 146.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055125 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 24: NB-4 - Immune response" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane" Nucleoplasm "HPA055125: AB_2682705" "unprognostic (1.51e-1)" "unprognostic (6.88e-3)" "unprognostic (2.70e-1)" "unprognostic (6.67e-2)" "unprognostic (7.96e-2)" "unprognostic (9.66e-3)" "unprognostic (1.16e-1)" "unprognostic (2.58e-3)" "unprognostic (3.80e-1)" "unprognostic (8.34e-3)" "unprognostic (4.29e-3)" "unprognostic (1.02e-1)" "prognostic favorable (1.11e-5)" "unprognostic (1.63e-1)" "unprognostic (1.06e-1)" "unprognostic (2.28e-2)" "unprognostic (2.37e-2)" 21.8 48.4 41.8 19.6 42.5 40.1 28.1 38.4 48.7 23.8 47.1 23.8 30.4 16.7 38.1 16.4 35.8 23.8 19.1 43.8 43.2 59.9 67.8 26.2 35.4 38.5 38.8 21.8 35.5 53.0 29.5 32.1 39.3 25.0 24.3 25.6 52.3 20.2 15.7 18.0 30.7 15.9 37.8 29.8 29.3 23.8 41.1 46.5 54.2 21.3 33.6 26.2 17.2 39.0 7.2 12.9 9.5 17.4 17.5 24.4 19.4 11.7 20.3 15.2 24.6 11.1 14.1 31.1 22.3 11.8 21.3 12.3 15.6 16.2 24.4 35.9 35.7 25.3 16.3 22.1 27.6 43.8 25.6 15.7 20.2 10.9 32.0 31.0 25.1 43.1 25.8 42.2 17.1 15.9 36.3 58.0 8.9 28.9 13.2 21.7 9.5 29.2 18.3 10.6 11.8 18.4 15.6 13.8 34.9 18.6 6.7 47.6 19.5 11.9 13.5 22.3 18.0 55.8 53.0 23.1 12.7 27.1 10.6 137.8 91.6 120.6 84.5 96.5 76.4 107.1 88.4 92.8 102.1 106.6 101.5 93.3 249.6 115.8 85.0 90.0 159.8 93.6 41.8 42.5 38.4 48.7 43.8 43.2 38.5 38.8 39.3 37.8 41.1 39.0 24.5 32.1 35.4 12.7 36.5 13.4 25.0 36.9 29.0 16.0 24.6 25.1 11.0 24.3 31.6 36.8 18.8 82.7 42.7 31.7 123.3 19.3 146.8 83.5 11.4 20.7 24.7 39.2 25.6 31.6 49.2 23.2 16.3 15.6 43.1 25.3 29.3 50.8 38.0 10.1 22.3 30.6 38.7 41.5 31.5 99.9 16.8 36.1 32.0 3.7 39.5 24.6 42.2 5.5 17.9 16.8 35.9 15.1 29.7 31.2 81.0 130.9 89.0 14.2 13.1 14.0 15.8 48.6 27.2 15.5 14.9 108.9 35.4 18.1 23.1 36.2 CCDC62 "CT109, ERAP75, FLJ40344, TSP-NY" ENSG00000130783 "Coiled-coil domain containing 62" Q6P9F0 12 122774526-122827528 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "testis: 70.0" "Group enriched" "Detected in some" 13 "Early spermatids: 259.2;Late spermatids: 75.0;Spermatocytes: 188.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "U-2 OS: 2.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA039021, HPA058741" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 78: Testis - Spermatogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Nucleoplasm, Plasma membrane" "HPA039021: AB_10673604, HPA058741: AB_2683805" "unprognostic (3.39e-2)" "unprognostic (4.16e-2)" "unprognostic (1.46e-2)" "unprognostic (7.48e-2)" "unprognostic (1.58e-2)" "unprognostic (9.37e-2)" "unprognostic (1.65e-1)" "unprognostic (7.09e-2)" "unprognostic (1.97e-1)" "unprognostic (1.48e-1)" "unprognostic (2.21e-4)" "unprognostic (5.23e-1)" "unprognostic (6.39e-6)" "unprognostic (2.78e-2)" "unprognostic (6.18e-2)" "unprognostic (7.27e-2)" "unprognostic (3.25e-4)" 0.2 0.3 1.2 0.2 1.3 0.2 0.1 0.7 1.8 0.3 0.0 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 1.3 0.5 0.1 0.1 0.1 0.3 0.6 0.4 0.1 0.1 0.3 0.7 0.0 0.7 0.1 0.1 1.4 0.1 0.1 0.7 0.4 0.2 0.1 0.2 0.5 0.1 70.0 0.5 0.2 0.1 0.3 0.3 0.1 0.1 2.0 0.1 0.1 0.1 0.3 0.0 0.3 0.3 0.0 0.1 0.3 0.1 0.0 0.2 0.8 0.0 0.0 0.1 0.0 0.2 0.0 0.1 0.2 0.3 0.9 0.1 0.0 0.0 0.6 0.8 0.1 0.3 0.4 0.1 0.1 0.0 0.7 0.3 0.2 0.4 0.1 0.0 1.2 0.1 0.0 0.5 0.8 0.2 0.0 0.2 0.1 0.5 0.0 0.0 0.3 0.4 0.2 0.0 0.6 0.1 0.2 2.9 0.1 0.1 0.3 0.3 0.2 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.1 0.3 0.0 1.2 1.3 0.7 1.8 1.3 0.5 0.6 0.4 0.7 0.2 0.5 2.0 0.5 0.0 0.0 9.1 2.1 0.5 0.2 0.1 0.6 1.4 0.4 0.5 1.0 0.0 0.0 0.0 4.2 0.1 0.6 0.1 0.0 0.3 259.2 0.5 0.4 0.4 0.0 0.0 11.7 0.2 0.6 0.2 0.0 0.7 0.0 0.2 0.0 0.0 0.1 1.7 8.1 0.2 0.0 0.3 1.7 75.0 3.1 1.3 1.8 3.7 0.2 0.5 1.0 5.0 8.0 0.1 0.0 2.6 0.3 0.5 0.1 0.0 0.0 1.3 13.1 0.5 0.2 188.2 2.9 0.4 0.9 0.0 0.3 0.2 0.3 0.2 CCDC93 FLJ10996 ENSG00000125633 "Coiled-coil domain containing 93" Q567U6 2 117915478-118014133 "Predicted intracellular proteins, Transporters" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054183 Approved Enhanced "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA054183: AB_2682408" "unprognostic (1.47e-1)" "unprognostic (6.55e-2)" "unprognostic (8.29e-2)" "unprognostic (1.02e-2)" "unprognostic (3.32e-2)" "unprognostic (2.47e-3)" "prognostic unfavorable (2.97e-6)" "unprognostic (2.51e-1)" "unprognostic (8.12e-2)" "unprognostic (8.99e-2)" "unprognostic (1.52e-3)" "unprognostic (8.56e-2)" "unprognostic (4.87e-1)" "unprognostic (1.79e-2)" "unprognostic (2.67e-1)" "prognostic unfavorable (9.66e-4)" "unprognostic (2.40e-2)" 10.2 14.5 9.3 10.4 8.5 21.7 9.6 9.6 12.7 9.1 15.0 11.3 11.9 8.2 9.8 7.4 9.3 7.1 21.3 8.4 9.4 9.8 7.8 11.8 10.3 9.7 9.0 13.3 13.0 15.9 16.1 8.1 10.3 7.6 10.6 26.0 9.1 8.4 12.9 11.0 12.8 8.1 8.4 12.1 9.1 12.1 11.5 10.1 11.9 10.3 10.1 8.6 8.1 8.5 18.7 8.1 22.0 19.4 31.2 21.3 18.5 21.8 14.2 14.0 14.3 17.7 11.7 15.9 14.5 17.1 24.9 15.8 12.8 11.2 18.1 20.8 13.0 20.1 15.5 23.9 13.7 22.1 22.0 14.6 11.5 21.9 25.9 19.4 15.0 18.9 11.1 11.0 15.8 8.1 14.0 23.8 9.9 13.4 13.0 17.6 17.2 10.7 11.5 19.6 17.4 10.3 14.2 10.6 15.1 19.6 8.9 13.5 21.2 23.9 20.0 20.4 15.3 14.3 16.0 24.7 13.8 16.1 14.2 2.9 1.6 1.8 2.1 2.1 2.0 1.6 1.5 1.8 1.2 1.4 2.0 1.7 1.7 1.7 1.3 0.5 0.7 1.0 9.3 8.5 9.6 12.7 8.4 9.4 9.7 9.0 10.3 8.4 11.5 8.5 17.4 19.2 28.2 61.0 28.6 17.6 14.6 11.2 9.6 32.0 12.4 10.0 43.0 7.2 17.5 1.8 47.9 12.6 31.9 21.5 9.8 24.0 4.5 14.9 15.2 16.5 16.7 9.9 57.1 16.7 8.5 14.7 11.7 17.0 15.2 25.1 12.8 6.0 15.2 20.2 60.6 11.4 10.2 16.3 15.9 10.6 13.7 19.9 3.6 32.8 19.9 13.8 20.6 53.3 37.9 32.0 11.9 14.3 19.4 13.9 17.1 9.4 16.3 36.0 6.6 21.4 15.0 46.0 31.1 10.1 16.1 12.9 24.3 12.8 14.0 15.0 CCR2 "CC-CKR-2, CD192, CKR2, CMKBR2, FLJ78302, MCP-1-R" ENSG00000121807 "C-C motif chemokine receptor 2" P41597 3 46353744-46360940 "CD markers, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Host-virus interaction, Inflammatory response" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 25.9" "Cell type enhanced" "Detected in some" "dendritic cells: 40.4;Kupffer cells: 43.1;Macrophages: 25.2;monocytes: 34.9;Plasma cells: 26.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "basophil: 560.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Karpas-707: 185.5;THP-1: 89.8;U-266/70: 416.5;U-266/84: 177.7" "Not detected" "Not detected" "Region enhanced" "Detected in single" "spinal cord: 2.4" "CAB003793, HPA063255" Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Nucleoli fibrillar center" "CAB003793: AB_344889, HPA063255: " "unprognostic (1.09e-2)" "unprognostic (6.28e-4)" "unprognostic (3.49e-2)" "unprognostic (6.35e-4)" "unprognostic (1.89e-2)" "unprognostic (4.16e-4)" "unprognostic (8.06e-2)" "prognostic favorable (5.87e-4)" "unprognostic (6.33e-2)" "unprognostic (3.27e-2)" "unprognostic (3.12e-1)" "unprognostic (1.56e-1)" "unprognostic (5.52e-3)" "unprognostic (1.29e-1)" "unprognostic (3.35e-2)" "unprognostic (4.88e-2)" "unprognostic (4.19e-1)" 2.6 1.9 0.1 25.9 0.1 1.9 3.1 0.1 0.2 1.6 0.3 4.6 7.5 1.2 0.9 1.2 1.2 3.4 1.1 0.1 0.1 1.2 2.1 5.8 11.6 0.4 0.2 1.1 0.8 0.3 0.2 0.8 0.2 1.2 5.1 0.0 3.1 1.7 0.5 1.9 5.7 7.1 0.3 20.4 5.2 1.0 0.2 4.3 1.1 0.5 7.2 5.5 1.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 2.7 0.0 185.5 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.2 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 89.8 0.0 0.0 0.0 0.0 0.3 416.5 177.7 0.0 0.1 3.3 0.1 560.9 146.2 2.6 11.9 12.8 89.2 7.9 24.3 20.2 145.2 1.8 0.6 0.7 3.8 14.0 0.4 113.6 11.4 81.6 0.1 0.1 0.1 0.2 0.1 0.1 0.4 0.2 0.2 0.3 0.2 0.3 0.1 0.0 1.3 0.0 5.8 0.3 0.0 0.0 0.6 0.0 0.1 0.1 0.3 1.5 0.0 0.0 0.0 0.1 40.4 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 4.4 0.0 0.0 0.0 0.4 1.1 0.1 0.0 0.0 1.8 0.9 0.8 0.0 0.0 0.0 0.0 43.1 10.5 0.7 0.0 25.2 0.0 0.0 34.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 26.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.0 0.0 8.2 0.1 0.1 0.0 CCT3 "Cctg, TRIC5" ENSG00000163468 "Chaperonin containing TCP1 subunit 3" P49368 1 156308968-156367873 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA006543 Approved Approved "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA006543: AB_1078426" "unprognostic (2.14e-2)" "unprognostic (3.20e-3)" "unprognostic (1.66e-1)" "unprognostic (6.00e-3)" "unprognostic (8.39e-3)" "unprognostic (3.14e-3)" "prognostic unfavorable (3.87e-7)" "unprognostic (4.43e-3)" "unprognostic (2.78e-1)" "unprognostic (1.16e-1)" "unprognostic (5.44e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (6.34e-4)" "unprognostic (7.16e-2)" "unprognostic (5.76e-2)" "unprognostic (5.67e-2)" "unprognostic (1.10e-1)" 85.3 122.3 121.4 103.0 125.8 79.5 119.4 132.2 176.7 77.1 139.0 95.3 87.2 93.6 77.1 106.9 119.9 67.4 100.8 125.3 135.5 114.5 108.3 60.1 123.9 129.4 126.1 113.5 82.3 120.4 65.3 93.3 129.5 86.6 112.9 135.7 74.9 89.8 134.8 93.8 83.3 137.3 132.4 67.1 80.7 120.3 130.2 129.1 87.6 120.8 148.5 136.7 70.6 143.8 432.3 562.3 324.3 311.9 352.5 261.2 419.7 388.8 315.9 617.9 378.0 611.1 396.3 689.5 442.3 337.9 392.5 395.5 1045.2 519.9 519.1 384.3 660.6 437.6 438.6 579.2 261.9 547.7 357.2 333.7 312.4 556.6 514.7 303.3 531.6 425.3 795.2 250.1 375.5 603.5 688.2 372.1 656.4 859.5 702.1 587.3 314.5 771.1 496.9 349.9 434.9 448.1 347.0 635.0 388.7 531.0 560.2 707.3 366.1 249.0 373.0 263.3 717.1 457.5 808.2 975.7 288.1 349.1 408.1 75.1 107.1 49.0 129.0 137.0 171.2 142.1 144.3 138.8 171.7 156.8 177.0 156.7 14.9 145.8 146.8 120.8 164.3 222.3 121.4 125.8 132.2 176.7 125.3 135.5 129.4 126.1 129.5 132.4 130.2 143.8 82.8 54.5 62.5 18.3 104.8 144.9 241.1 247.4 119.5 124.5 133.2 118.5 121.1 98.7 132.3 90.1 106.3 226.7 100.5 71.7 113.5 208.6 111.9 118.4 137.4 122.4 125.3 134.0 29.7 183.2 217.8 113.9 70.8 86.6 73.0 180.1 74.6 88.4 162.6 74.0 34.6 93.8 193.3 83.0 96.5 226.7 83.6 78.1 112.1 22.5 153.6 158.1 105.0 37.2 41.9 199.1 78.8 88.0 95.8 169.0 115.9 212.3 137.6 244.3 118.3 110.3 145.4 410.0 232.4 123.1 159.8 184.6 112.1 347.9 149.8 157.9 CD109 "CPAMD7, DKFZp762L1111, FLJ38569" ENSG00000156535 "CD109 molecule" Q6YHK3 6 73695785-73828316 "CD markers, Plasma proteins, Predicted membrane proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 17 "parathyroid gland: 330.4" "Cell type enhanced" "Detected in many" "Adipocytes: 65.3;Basal respiratory cells: 62.8;Hofbauer cells: 45.0;Squamous epithelial cells: 51.4;Suprabasal keratinocytes: 43.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC TERT1: 206.4;BJ hTERT+: 126.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA008992, HPA015723" Enhanced Supported "Plasma membrane,Cytosol" NA NA 180000000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA008992: , HPA015723: AB_2732415" "unprognostic (2.28e-1)" "unprognostic (1.03e-1)" "unprognostic (7.76e-2)" "unprognostic (1.52e-2)" "unprognostic (9.17e-3)" "unprognostic (1.36e-1)" "unprognostic (1.03e-3)" "unprognostic (1.23e-3)" "unprognostic (7.49e-2)" "unprognostic (2.47e-1)" "unprognostic (1.15e-3)" "unprognostic (8.81e-2)" "prognostic unfavorable (2.65e-4)" "prognostic unfavorable (7.96e-5)" "unprognostic (9.50e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (4.68e-4)" 8.6 1.1 2.3 2.4 2.5 2.8 5.5 2.1 2.1 9.9 0.7 6.9 1.3 12.5 5.6 10.2 3.2 4.1 5.8 2.0 4.0 7.0 1.1 6.6 1.0 3.2 3.6 0.7 0.5 330.4 0.4 6.5 3.5 3.6 2.9 0.2 3.4 2.5 1.2 18.9 2.2 12.6 3.7 2.1 1.1 1.8 2.5 3.1 1.3 3.3 2.2 4.5 7.4 3.1 35.6 29.4 1.5 0.1 48.2 206.4 0.0 30.5 126.0 9.0 18.4 0.1 20.2 0.0 19.7 63.5 19.5 96.5 3.5 60.9 12.1 8.5 5.5 11.5 21.0 5.8 10.1 0.0 0.3 60.7 52.4 18.6 68.7 34.2 71.6 3.9 0.0 0.2 45.0 0.8 0.8 0.0 2.4 0.3 18.9 2.6 8.4 40.6 4.8 3.6 0.0 0.1 68.6 0.7 30.8 1.3 0.8 5.8 68.7 96.8 10.1 17.2 28.5 0.7 17.9 0.1 40.3 0.1 89.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.0 2.3 2.5 2.1 2.1 2.0 4.0 3.2 3.6 3.5 3.7 2.5 3.1 65.3 3.2 1.7 39.8 1.1 41.4 8.4 62.8 35.9 0.3 2.2 2.2 13.0 0.0 16.3 0.0 0.0 0.4 1.2 0.1 1.9 0.1 23.4 10.8 10.5 38.0 0.0 7.6 4.0 0.0 0.5 25.0 0.5 15.0 2.5 0.0 21.0 0.6 45.0 0.0 3.3 0.1 4.1 2.7 28.5 21.0 0.6 13.5 23.2 19.7 3.3 0.0 0.0 1.5 1.0 0.4 0.0 0.0 1.7 10.8 0.0 23.5 16.0 0.2 0.0 7.4 13.2 1.0 3.5 51.4 43.8 1.4 4.6 1.4 0.2 7.2 CD164L2 ENSG00000174950 "CD164 molecule like 2" Q6UWJ8 1 27379176-27383333 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 19.9;fallopian tube: 30.0;salivary gland: 13.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 28.5;Endometrial ciliated cells: 53.6;Respiratory ciliated cells: 146.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.2;CAPAN-2: 4.1;HaCaT: 1.9;HBEC3-KT: 2.2;hTCEpi: 2.8;SK-BR-3: 2.6;T-47d: 1.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062915 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA062915: AB_2684903" "unprognostic (8.97e-3)" "unprognostic (2.15e-2)" "unprognostic (3.56e-2)" "unprognostic (1.36e-2)" "unprognostic (1.04e-1)" "prognostic favorable (1.64e-5)" "unprognostic (7.81e-3)" "unprognostic (4.47e-2)" "unprognostic (1.39e-1)" "unprognostic (1.65e-2)" "unprognostic (4.07e-2)" "unprognostic (5.91e-6)" "unprognostic (1.33e-2)" "unprognostic (6.42e-2)" "unprognostic (1.34e-2)" "unprognostic (2.71e-2)" 0.1 0.1 0.3 0.0 0.3 0.0 2.5 0.2 0.4 4.9 1.0 0.2 0.0 0.3 0.5 19.9 30.0 0.1 0.0 0.4 0.3 0.9 0.2 5.1 0.0 2.0 1.5 0.0 0.8 0.8 3.4 0.0 0.6 4.1 0.2 0.0 13.5 0.3 0.0 11.1 0.1 0.0 0.8 0.0 0.7 0.5 0.2 0.9 0.4 0.0 1.8 0.0 9.3 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 1.9 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 2.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.4 1.1 0.1 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 2.6 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.2 0.4 0.4 0.3 2.0 1.5 0.6 0.8 0.2 0.4 0.2 0.0 3.7 0.0 0.2 2.9 9.6 12.9 28.5 0.0 5.7 14.4 0.9 0.0 10.1 0.0 0.0 0.0 0.3 0.8 0.0 0.1 0.2 53.6 0.5 1.5 0.0 0.0 0.2 0.2 0.1 0.5 0.0 1.0 0.0 0.0 1.1 0.0 0.1 0.0 0.3 0.5 12.2 0.0 0.4 1.6 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.0 1.2 3.4 0.0 0.1 146.1 0.0 0.0 0.1 2.8 0.1 1.0 9.3 2.8 0.0 0.4 0.0 0.5 4.4 CD248 "CD164L1, TEM1" ENSG00000174807 "CD248 molecule" Q9HCU0 11 66314494-66317044 "CD markers, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 237.3;breast: 155.5" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 155.4;Fibroblasts: 166.9;Leydig cells: 74.9;Smooth muscle cells: 59.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "naive CD8 T-cell: 21.8" "Lineage enriched" "Detected in single" 144 "T-cells: 21.8" "Cell line enhanced" "Detected in many" "ASC diff: 492.4;ASC TERT1: 481.9;BJ: 222.2;BJ hTERT+: 330.1;fHDF/TERT166: 451.1;HSkMC: 516.8;U-2197: 794.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA051856 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 43000000 "Cluster 32: T-cells - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA051856: AB_2681640" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.95e-2)" "unprognostic (2.77e-2)" "unprognostic (1.14e-2)" "unprognostic (2.61e-1)" "unprognostic (7.21e-3)" "unprognostic (1.36e-2)" "unprognostic (1.01e-1)" "unprognostic (2.82e-2)" "unprognostic (6.31e-2)" "unprognostic (4.77e-2)" "prognostic unfavorable (2.69e-7)" "unprognostic (1.90e-2)" "unprognostic (2.92e-2)" "unprognostic (1.25e-1)" "unprognostic (1.30e-2)" 237.3 12.9 2.3 39.3 2.4 0.4 155.5 2.2 4.0 87.2 1.5 31.7 7.8 52.2 6.9 19.6 60.8 32.3 30.3 2.2 2.2 18.7 3.6 36.5 6.2 2.4 2.6 23.9 11.7 3.3 8.8 67.4 2.2 17.8 7.4 0.4 18.2 19.4 15.8 51.0 27.2 26.5 2.0 7.2 26.3 5.0 3.9 5.3 35.0 6.5 2.6 63.4 61.5 2.0 0.0 0.0 4.9 0.0 492.4 481.9 0.3 222.2 330.1 16.3 15.1 0.1 0.0 0.0 5.8 451.1 0.0 0.0 0.2 0.2 3.5 0.0 0.0 0.0 0.1 3.3 97.5 0.0 0.0 516.8 0.0 21.4 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 3.4 3.2 2.5 0.0 1.4 9.5 0.0 0.2 0.0 0.0 2.8 7.6 0.0 1.2 0.0 13.4 0.5 0.4 0.1 0.0 0.8 794.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 2.6 0.0 0.1 3.1 21.8 0.0 0.0 0.0 0.0 0.0 2.5 2.3 2.4 2.2 4.0 2.2 2.2 2.4 2.6 2.2 2.0 3.9 2.0 15.0 0.0 0.0 1.3 1.3 12.5 0.0 0.0 0.6 0.1 1.2 1.5 2.2 0.0 0.0 0.0 0.0 2.7 0.5 0.0 0.0 0.2 0.3 5.3 155.4 5.8 0.0 0.0 0.0 0.0 2.5 166.9 13.3 3.1 0.0 0.0 2.5 0.0 6.0 0.0 0.0 0.0 0.0 0.3 14.4 2.3 74.9 1.6 12.4 1.9 0.6 2.9 1.0 0.0 0.0 0.3 0.0 20.3 0.1 0.0 0.0 0.1 0.0 0.1 32.9 5.5 59.3 0.1 0.1 0.8 8.2 4.4 6.9 1.1 0.0 0.1 CD2AP CMS ENSG00000198087 "CD2 associated protein" Q9Y5K6 6 47477789-47627263 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 204.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 9.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003267, HPA003326, CAB004352" Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 58000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Centriolar satellite" "CAB004352: AB_627009, HPA003267: AB_1078458, HPA003326: AB_1078457" "unprognostic (5.98e-2)" "unprognostic (1.08e-2)" "unprognostic (1.75e-2)" "unprognostic (1.74e-1)" "unprognostic (1.31e-1)" "unprognostic (1.77e-2)" "unprognostic (1.74e-3)" "unprognostic (1.19e-1)" "unprognostic (6.71e-2)" "unprognostic (2.69e-2)" "prognostic unfavorable (5.53e-5)" "unprognostic (2.21e-1)" "unprognostic (3.09e-3)" "unprognostic (6.12e-3)" "unprognostic (1.74e-1)" "unprognostic (1.84e-1)" "prognostic favorable (7.57e-5)" 14.0 10.5 3.4 15.0 3.4 14.3 17.8 6.3 4.6 18.1 8.8 40.0 56.9 12.0 13.2 19.2 14.1 15.0 7.7 2.7 3.8 34.1 20.2 17.1 15.9 4.3 3.9 6.4 20.2 35.6 6.0 21.6 4.7 19.7 36.9 6.9 17.0 13.5 6.9 18.0 59.5 10.9 4.3 13.7 40.4 9.4 3.9 34.0 18.2 10.3 17.4 30.1 10.1 4.6 58.0 22.5 6.9 14.3 9.4 13.6 54.8 13.9 16.9 18.5 23.3 37.3 39.9 74.5 56.9 18.2 24.0 21.2 23.0 34.7 29.9 29.9 37.2 41.3 18.4 33.6 12.5 23.3 15.4 9.7 32.1 17.7 25.5 35.7 30.1 24.4 73.5 23.2 16.9 18.2 44.6 8.7 20.3 69.6 8.1 23.6 17.6 34.1 115.6 101.7 20.9 8.1 27.9 36.9 27.7 31.1 35.0 14.8 36.2 36.9 30.8 12.0 39.9 17.5 31.3 52.6 39.4 12.4 19.2 1.8 0.5 3.2 1.2 0.4 1.8 0.9 1.0 1.1 1.2 1.0 0.9 1.5 0.1 3.1 0.4 9.9 0.9 0.5 3.4 3.4 6.3 4.6 2.7 3.8 4.3 3.9 4.7 4.3 3.9 4.6 81.7 96.1 67.1 32.0 40.5 32.2 52.1 26.5 39.9 10.0 40.4 26.4 17.2 35.8 68.9 71.7 16.7 53.0 96.1 204.1 21.5 84.6 10.4 97.9 25.0 56.6 55.8 42.9 40.7 98.0 17.1 20.6 101.4 136.7 24.1 28.5 37.5 24.2 17.4 15.2 45.3 97.3 40.7 26.2 12.6 10.5 16.8 30.6 14.2 83.4 18.0 12.5 22.6 28.6 30.8 151.3 114.0 10.9 27.7 89.0 182.3 67.4 60.0 13.0 26.3 34.9 27.8 38.9 27.2 44.2 41.1 40.9 29.4 48.0 68.8 143.6 CD33 "FLJ00391, p67, SIGLEC-3, SIGLEC3" ENSG00000105383 "CD33 molecule" P20138 19 51225064-51243860 "CD markers, FDA approved drug targets, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 32.4;lymphoid tissue: 23.9" "Group enriched" "Detected in some" 6 "granulocytes: 76.0;Hofbauer cells: 78.8;Kupffer cells: 131.2;Langerhans cells: 41.4;Macrophages: 53.5;monocytes: 65.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 7 "classical monocyte: 166.5;intermediate monocyte: 122.0;myeloid DC: 213.5;non-classical monocyte: 57.8" "Group enriched" "Detected in many" 9 "dendritic cells: 213.5;monocytes: 166.5" "Cell line enhanced" "Detected in some" "HEL: 86.1;HL-60: 115.6;HMC-1: 82.4;NB-4: 55.2;RPMI-8226: 62.5;THP-1: 67.0;U-937: 84.1" "CAB011442, HPA035832, HPA064807, CAB079996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 3400000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Nucleoplasm, Plasma membrane" "CAB011442: , CAB079996: , HPA035832: AB_2674808, HPA064807: AB_2685356" "unprognostic (1.18e-2)" "unprognostic (1.45e-2)" "unprognostic (2.80e-2)" "unprognostic (7.14e-2)" "unprognostic (3.71e-1)" "unprognostic (9.43e-2)" "unprognostic (2.59e-1)" "unprognostic (5.90e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-1)" "unprognostic (2.53e-1)" "unprognostic (6.28e-2)" "unprognostic (6.88e-4)" "unprognostic (7.79e-2)" "unprognostic (3.35e-2)" "unprognostic (6.49e-2)" "unprognostic (1.67e-1)" 7.9 3.4 1.1 11.2 1.2 32.4 2.5 1.5 1.6 3.0 2.5 3.2 3.3 1.7 1.3 2.0 2.5 6.6 2.0 1.1 1.8 1.4 5.5 12.6 10.1 2.5 1.6 1.4 1.4 1.2 0.9 6.9 2.4 1.4 4.2 0.2 1.8 2.6 0.9 2.7 4.4 7.1 1.9 23.9 2.3 1.0 2.3 3.5 0.9 0.8 3.5 6.2 1.3 3.6 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.2 0.0 5.5 0.4 0.0 1.3 0.3 0.0 0.2 0.0 0.1 0.1 86.1 0.3 0.0 0.0 115.6 82.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 16.2 21.2 0.2 0.0 0.0 55.2 0.2 0.0 25.9 0.0 4.4 62.5 0.4 0.0 0.2 0.0 0.0 0.1 0.4 0.0 0.0 67.0 0.7 14.0 1.1 1.8 0.1 0.3 7.6 0.2 9.6 84.1 0.4 17.9 166.5 11.0 0.3 122.0 0.4 0.1 0.2 0.5 213.5 0.4 0.3 0.2 20.5 15.5 57.8 6.3 1.1 77.8 1.1 1.2 1.5 1.6 1.1 1.8 2.5 1.6 2.4 1.9 2.3 3.6 0.7 0.0 6.7 0.0 1.0 1.8 0.5 0.0 0.0 0.2 1.4 0.4 0.8 0.0 0.6 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.7 0.1 0.1 3.0 0.0 4.2 0.0 0.0 0.5 1.1 0.0 0.1 76.0 0.1 5.3 0.7 78.8 0.0 0.0 0.0 0.0 131.2 41.4 1.7 0.3 53.5 1.8 11.2 65.0 0.2 1.0 0.5 0.2 0.0 0.0 0.0 0.3 0.4 0.0 0.2 0.7 0.6 0.0 1.1 0.3 0.7 0.5 0.0 1.0 0.8 2.5 0.1 0.0 0.4 CD37 TSPAN26 ENSG00000104894 "CD37 molecule" P11049 19 49335171-49343335 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 155.2;intestine: 116.3;lymphoid tissue: 235.7" "Cell type enhanced" "Detected in many" "B-cells: 1643.9;dendritic cells: 489.6;Hofbauer cells: 345.3;Langerhans cells: 358.4;Macrophages: 319.7;monocytes: 365.0;NK-cells: 394.4;T-cells: 390.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 306.4;HMC-1: 290.0;RPMI-8226: 110.7;THP-1: 109.0;U-698: 69.4;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB002492, HPA032120, HPA032121" Enhanced Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus" "Plasma membrane" "CAB002492: AB_563554, HPA032120: AB_2674162, HPA032121: AB_2674163" "unprognostic (4.30e-3)" "unprognostic (2.39e-3)" "unprognostic (8.85e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.46e-2)" "unprognostic (4.59e-3)" "unprognostic (1.76e-1)" "unprognostic (6.23e-2)" "unprognostic (5.34e-2)" "unprognostic (2.23e-1)" "unprognostic (1.22e-1)" "unprognostic (3.06e-1)" "unprognostic (2.45e-3)" "unprognostic (7.12e-2)" "unprognostic (3.35e-2)" "unprognostic (7.22e-2)" "unprognostic (7.71e-2)" 16.6 7.0 7.5 100.2 7.4 155.2 6.5 9.4 13.7 4.2 5.9 13.9 8.2 3.7 0.7 7.3 5.8 13.9 5.2 6.3 11.4 7.6 6.4 46.9 215.0 17.0 12.0 1.7 3.2 1.8 3.4 15.1 16.5 6.9 3.8 0.3 11.5 2.8 1.9 4.1 116.3 3.9 16.7 235.7 14.8 7.4 15.6 57.5 8.3 2.4 88.0 19.1 5.2 28.7 0.2 0.6 1.5 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 306.4 0.1 0.0 0.0 0.6 0.0 0.0 0.0 49.5 0.2 53.1 0.0 0.5 0.0 9.4 290.0 0.0 0.0 0.0 0.0 0.2 0.0 18.5 2.6 16.3 0.0 0.0 0.4 5.8 0.2 0.0 0.0 2.9 0.3 110.7 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.3 109.0 0.8 0.3 1.0 0.2 0.0 0.3 0.1 69.4 0.2 81.4 0.1 550.2 658.2 829.6 353.2 601.6 357.4 1511.6 426.3 376.2 449.7 1722.2 435.3 368.6 903.8 321.8 747.8 586.3 467.1 816.2 7.5 7.4 9.4 13.7 6.3 11.4 17.0 12.0 16.5 16.7 15.6 28.7 7.1 9.6 14.3 0.3 1643.9 11.7 1.3 0.1 4.6 12.1 4.6 12.1 1.6 2.8 2.5 1.8 6.2 1.9 489.6 2.2 0.0 0.5 94.2 1.2 1.9 9.7 1.2 67.7 0.1 0.0 2.3 6.9 11.7 1.5 264.6 0.3 11.4 4.1 345.3 0.0 0.2 1.7 0.0 272.0 358.4 221.3 2.8 319.7 28.4 21.5 365.0 1.1 394.4 0.0 0.1 0.0 8.0 0.7 119.8 1.1 0.6 2.9 0.9 6.3 0.0 3.2 5.7 1.1 1.3 2.6 11.8 2.9 390.3 0.9 1.9 1.1 CD3G ENSG00000160654 "CD3g molecule" P09693 11 118344344-118355161 "CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "lymphoid tissue: 94.7" "Group enriched" "Detected in many" 11 "dendritic cells: 139.6;T-cells: 294.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 21 "gdT-cell: 229.0;MAIT T-cell: 135.6;memory CD4 T-cell: 187.3;memory CD8 T-cell: 197.3;naive CD4 T-cell: 192.6;naive CD8 T-cell: 241.7;T-reg: 200.0" "Lineage enriched" "Detected in many" 26 "T-cells: 241.7" "Group enriched" "Detected in some" 52 "JURKAT: 70.9;MOLT-4: 193.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB017520, HPA038494" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "CAB017520: AB_831094, HPA038494: AB_2676044" "prognostic favorable (6.33e-4)" "prognostic favorable (2.61e-4)" "unprognostic (4.58e-3)" "unprognostic (3.12e-5)" "unprognostic (6.30e-2)" "prognostic favorable (3.00e-4)" "unprognostic (1.98e-2)" "unprognostic (1.54e-2)" "unprognostic (8.25e-3)" "unprognostic (1.08e-3)" "unprognostic (1.54e-2)" "unprognostic (2.19e-1)" "prognostic unfavorable (9.33e-5)" "unprognostic (1.60e-1)" "unprognostic (2.37e-2)" "unprognostic (4.13e-2)" "unprognostic (2.10e-3)" 0.7 0.8 0.6 10.5 0.8 1.3 1.0 1.1 0.8 0.7 1.1 2.3 3.3 0.5 0.6 1.4 0.9 2.5 0.5 0.5 0.4 0.6 1.6 2.8 27.9 0.9 0.6 0.4 0.5 0.2 0.0 0.3 0.8 0.9 2.7 0.4 1.6 0.3 10.5 0.9 4.6 0.6 0.3 11.5 4.1 0.4 0.8 94.7 0.6 0.3 20.4 3.0 0.4 1.9 0.2 0.2 0.1 0.2 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.2 0.7 0.2 0.0 0.3 0.2 0.0 0.0 0.0 0.6 0.6 0.0 0.4 0.2 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.0 70.9 2.5 0.3 0.0 0.6 193.8 1.3 0.2 0.0 0.1 0.2 0.0 0.3 0.0 0.1 0.5 0.2 0.0 1.1 0.1 0.0 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.2 0.7 0.3 0.2 0.2 0.1 9.2 1.2 1.2 229.0 0.6 135.6 0.8 187.3 197.3 0.6 0.9 192.6 241.7 6.4 1.4 1.2 1.5 200.0 90.4 0.6 0.8 1.1 0.8 0.5 0.4 0.9 0.6 0.8 0.3 0.8 1.9 3.2 3.2 6.9 0.0 7.8 2.3 0.1 0.0 1.8 0.2 2.0 2.9 0.8 1.5 1.9 0.0 0.0 0.1 139.6 0.4 0.0 0.3 1.0 0.4 0.4 1.4 0.0 3.4 0.1 0.0 0.0 2.3 13.7 0.4 6.3 0.0 4.2 1.7 0.1 0.0 0.1 0.2 0.0 3.8 5.8 1.4 0.0 7.7 5.4 1.0 8.1 0.0 14.4 0.0 0.3 0.0 0.1 0.0 18.5 0.0 0.0 0.6 0.7 0.8 0.0 1.3 1.6 0.2 0.4 0.6 2.4 0.3 294.0 0.1 0.3 0.0 CD40LG "CD154, CD40L, gp39, hCD40L, HIGM1, IMD3, TNFSF5, TRAP" ENSG00000102245 "CD40 ligand" P29965 X 136648158-136660390 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins, Predicted secreted proteins" Cytokine "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 15.5" "Cell type enriched" "Detected in some" 8 "T-cells: 76.6" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 5 "gdT-cell: 26.3;MAIT T-cell: 64.1;memory CD4 T-cell: 80.5;naive CD4 T-cell: 76.1" "Lineage enriched" "Detected in many" 39 "T-cells: 80.5" "Cell line enriched" "Detected in some" 15 "MOLT-4: 23.5" "Not detected" "Not detected" "Not detected" "Not detected" "HPA045827, HPA072480" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 776000 20000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Golgi apparatus, Plasma membrane" "HPA045827: AB_10959606, HPA072480: " "unprognostic (1.94e-5)" "unprognostic (1.24e-2)" "unprognostic (3.26e-1)" "unprognostic (1.27e-3)" "unprognostic (4.71e-2)" "unprognostic (3.56e-5)" "unprognostic (3.66e-2)" "unprognostic (5.48e-3)" "unprognostic (2.77e-1)" "unprognostic (2.14e-4)" "unprognostic (1.87e-1)" "unprognostic (1.55e-1)" "unprognostic (6.70e-4)" "unprognostic (2.15e-1)" "unprognostic (5.19e-2)" "unprognostic (2.36e-3)" "unprognostic (2.92e-2)" 0.8 0.3 0.1 7.9 0.0 1.9 1.1 0.2 0.2 0.9 0.2 1.9 1.8 0.3 0.2 1.0 0.4 2.0 0.2 0.1 0.2 0.4 1.0 2.4 15.5 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.2 0.8 3.1 0.0 0.6 0.3 0.1 0.6 3.8 0.6 0.0 4.9 2.0 0.3 0.1 15.5 0.5 0.2 14.8 2.5 0.4 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 0.3 26.3 0.1 64.1 0.1 80.5 11.7 0.2 0.0 76.1 0.7 1.3 0.8 0.1 0.1 10.5 13.6 0.1 0.0 0.2 0.2 0.1 0.2 0.1 0.1 0.2 0.0 0.1 0.2 0.6 0.0 2.4 0.0 2.4 1.3 0.0 0.0 0.0 0.0 0.4 0.5 0.3 0.0 0.6 0.0 0.0 0.0 4.5 0.0 0.0 0.0 3.9 0.0 0.0 0.6 0.0 1.7 0.0 0.0 0.0 0.6 2.6 0.0 1.3 0.0 1.1 0.3 0.1 0.0 0.0 0.0 0.0 0.6 4.0 8.9 0.0 2.9 1.8 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.4 0.0 0.0 0.0 0.6 0.7 0.0 0.0 0.1 2.0 0.0 76.6 0.0 0.0 0.1 CD44 "CD44R, CSPG8, HCELL, IN, MC56, MDU2, MDU3, MIC4, Pgp1" ENSG00000026508 "CD44 molecule (Indian blood group)" P16070 11 35138882-35232402 "Blood group antigen proteins, Cancer-related genes, CD markers, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Blood group antigen, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 504.2" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 999.7;Ductal cells: 992.1;Exocrine glandular cells: 869.6;Langerhans cells: 1934.2;Suprabasal keratinocytes: 1024.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 1650.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000112, CAB000316, HPA005785" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 1200000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" "Golgi apparatus" "CAB000112: , CAB000316: AB_2076596, HPA005785: AB_1078467" "unprognostic (5.33e-2)" "unprognostic (1.85e-1)" "unprognostic (4.97e-2)" "unprognostic (9.90e-3)" "unprognostic (3.50e-3)" "unprognostic (1.46e-2)" "unprognostic (1.56e-2)" "unprognostic (8.12e-2)" "unprognostic (1.57e-1)" "unprognostic (4.18e-2)" "unprognostic (1.51e-3)" "unprognostic (4.63e-2)" "prognostic unfavorable (1.78e-8)" "unprognostic (6.41e-2)" "unprognostic (4.14e-2)" "unprognostic (3.93e-2)" "unprognostic (7.98e-2)" 143.7 42.4 29.2 218.0 33.9 308.1 164.7 63.0 25.1 146.0 16.8 91.1 53.0 200.4 20.1 227.8 69.0 129.7 30.4 33.0 116.5 31.3 31.0 214.1 108.8 114.9 102.3 11.7 263.2 6.0 8.1 74.1 118.3 87.3 111.5 38.0 504.2 57.0 17.1 433.3 60.8 175.8 114.3 83.8 61.5 6.6 62.8 64.2 76.2 27.7 188.7 235.2 193.4 114.9 493.0 448.6 4.3 1.2 252.6 691.5 1.6 962.2 740.3 521.3 288.2 30.4 150.4 0.7 126.5 1350.2 1065.4 820.1 9.9 1013.9 716.4 110.3 6.2 18.9 198.3 0.3 262.3 254.6 1124.3 315.4 778.3 693.2 552.7 1650.0 184.3 0.1 4.0 157.9 518.9 3.0 25.6 166.9 9.8 8.7 136.4 1.4 89.3 7.5 777.4 138.1 2.0 1.4 185.2 5.5 462.8 38.6 25.7 15.1 547.3 646.6 120.0 815.8 1006.0 281.6 327.7 3.7 980.4 145.1 969.8 127.4 403.0 35.4 140.6 257.8 196.5 122.5 210.1 186.5 229.0 90.0 179.7 153.6 92.6 322.3 356.1 79.9 309.7 437.3 29.2 33.9 63.0 25.1 33.0 116.5 114.9 102.3 118.3 114.3 62.8 114.9 41.0 96.1 361.8 54.5 250.1 999.7 297.7 335.3 228.2 0.6 139.6 71.2 8.6 27.1 125.6 20.2 2.1 4.5 257.0 14.0 1.9 992.1 41.3 43.6 395.4 50.9 100.1 94.4 0.4 869.6 3.6 282.2 39.8 196.9 763.2 25.2 13.2 3.6 226.6 0.0 0.4 93.3 30.5 474.3 1934.2 24.3 22.4 523.9 604.7 8.4 594.2 29.6 62.8 0.5 11.2 813.1 10.9 0.4 216.3 386.7 6.0 1.6 18.8 2.0 157.8 197.2 227.9 0.4 0.4 279.3 1024.9 17.9 430.8 1.0 79.1 330.7 CD47 "IAP, MER6, OA3" ENSG00000196776 "CD47 molecule" Q08722 3 108043091-108091862 "CD markers, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 589.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016055, HPA044659" Approved Supported "Vesicles,Plasma membrane" NA NA 49000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Vesicles "CAB016055: AB_627086, HPA044659: AB_2679040" "unprognostic (3.54e-2)" "unprognostic (4.74e-2)" "unprognostic (3.19e-2)" "prognostic unfavorable (2.44e-4)" "unprognostic (4.49e-2)" "unprognostic (2.14e-1)" "unprognostic (2.05e-3)" "unprognostic (8.77e-3)" "unprognostic (7.35e-2)" "unprognostic (1.53e-1)" "unprognostic (1.69e-2)" "unprognostic (2.87e-1)" "prognostic unfavorable (1.69e-4)" "unprognostic (7.37e-2)" "unprognostic (3.78e-1)" "prognostic favorable (7.29e-5)" "unprognostic (1.83e-1)" 51.8 64.9 39.2 116.4 47.9 232.2 89.3 64.4 63.5 57.4 30.4 89.0 74.6 53.0 92.4 93.9 100.5 86.7 59.5 47.2 41.9 44.4 71.4 154.6 137.9 53.1 40.5 46.1 41.5 27.2 34.6 80.1 48.5 122.2 99.3 285.7 105.3 55.7 57.9 59.8 79.3 55.4 50.9 100.1 104.2 59.0 49.2 79.1 91.2 22.8 161.7 110.1 52.4 76.4 303.3 49.9 108.0 62.1 130.3 122.6 147.9 106.0 139.4 70.8 126.0 2.1 159.1 129.6 180.0 90.7 216.5 201.0 52.2 98.7 91.7 81.5 35.8 311.6 45.9 3.9 73.8 227.4 467.6 85.7 58.1 71.6 53.6 118.5 73.4 132.6 85.1 323.6 108.5 148.1 268.5 77.0 46.7 298.4 133.6 154.2 69.3 187.8 185.3 115.8 69.7 37.9 63.6 111.7 124.4 56.5 227.4 85.8 76.5 210.9 40.9 120.7 79.4 124.2 100.8 208.0 131.5 119.8 65.6 185.2 119.2 232.8 178.1 244.2 155.6 191.6 209.7 192.0 181.6 188.7 149.2 169.0 145.4 232.6 339.2 133.3 334.5 296.9 39.2 47.9 64.4 63.5 47.2 41.9 53.1 40.5 48.5 50.9 49.2 76.4 72.3 368.6 157.4 98.6 192.9 165.3 311.7 504.4 101.3 102.9 119.0 93.1 51.9 110.1 205.7 93.8 95.9 169.9 218.6 36.5 15.6 589.6 81.5 157.2 17.0 76.5 63.8 112.6 219.2 412.5 85.5 119.1 36.2 120.4 57.7 250.0 83.6 34.2 186.4 122.8 129.3 70.8 148.5 79.6 200.7 52.2 34.2 121.5 117.4 39.4 100.5 51.7 219.4 107.1 150.4 344.7 92.6 48.5 143.8 439.0 53.7 16.3 162.2 229.7 65.7 47.1 85.4 111.5 19.6 97.1 140.1 121.2 160.8 80.6 94.3 321.3 CD81 "TAPA-1, TAPA1, TSPAN28" ENSG00000110651 "CD81 molecule" P60033 11 2376177-2397397 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Adipocytes: 1003.1;Endometrial stromal cells: 1050.9;Muller glia cells: 809.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "memory B-cell: 148.9;naive B-cell: 137.2" "Lineage enriched" "Detected in all" 4 "B-cells: 148.9" "Cell line enhanced" "Detected in many" "ASC diff: 2960.6;fHDF/TERT166: 1752.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002507, HPA007234" Supported Supported "Plasma membrane,Cytosol" NA NA 400000 "Cluster 43: B-cells - Humoral immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "CAB002507: AB_563639, HPA007234: AB_1846333" "unprognostic (2.96e-1)" "unprognostic (3.40e-1)" "prognostic unfavorable (7.56e-4)" "unprognostic (1.84e-2)" "prognostic unfavorable (8.21e-5)" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.31e-1)" "unprognostic (2.09e-1)" "unprognostic (1.24e-1)" "prognostic favorable (3.86e-4)" "unprognostic (3.07e-3)" "unprognostic (2.08e-1)" "unprognostic (3.55e-2)" "unprognostic (1.67e-1)" "unprognostic (2.06e-1)" "unprognostic (2.06e-1)" 892.1 299.1 560.6 270.7 598.4 77.8 773.6 614.8 590.2 952.7 498.9 992.0 150.7 1384.0 960.5 364.3 853.1 534.5 937.9 511.1 615.8 636.6 1175.7 768.4 429.0 665.7 640.8 656.8 449.5 258.3 409.1 441.0 651.1 634.0 234.4 75.9 531.1 1602.0 214.3 511.1 423.1 978.5 694.1 631.3 494.3 316.9 655.1 158.9 564.6 227.6 278.6 749.2 763.4 734.4 337.0 342.0 268.5 413.4 2960.6 1668.4 224.8 621.0 1361.6 490.3 492.2 322.8 1.8 285.4 218.3 1752.6 312.5 430.5 167.3 442.2 199.9 135.6 517.8 43.7 117.1 0.3 976.4 188.2 359.8 1222.3 619.9 201.1 302.1 757.9 476.6 204.0 198.7 484.9 696.4 257.2 160.7 239.1 324.4 304.7 274.2 324.7 135.5 183.3 529.1 223.3 288.8 319.2 198.4 514.4 383.8 214.3 171.0 337.8 641.3 249.0 181.6 471.2 216.6 356.9 88.1 529.1 361.3 111.0 435.0 0.9 3.3 22.9 21.1 5.8 34.4 148.9 14.9 33.0 2.6 137.2 9.2 16.9 1.0 14.7 7.3 7.7 12.0 10.7 560.6 598.4 614.8 590.2 511.1 615.8 665.7 640.8 651.1 694.1 655.1 734.4 1003.1 243.6 270.0 95.0 88.2 179.8 391.8 89.7 26.2 82.7 325.6 452.0 277.4 167.3 102.3 207.8 27.1 21.8 267.1 20.0 35.2 105.7 15.9 365.4 1050.9 344.5 71.9 30.7 19.0 55.1 31.7 560.4 21.4 462.7 81.7 204.0 293.4 603.9 251.5 148.0 32.4 48.2 50.8 232.7 179.7 50.2 389.2 277.6 151.2 60.0 23.0 809.2 45.3 145.8 93.6 61.3 14.7 251.3 50.7 147.6 5.0 29.9 85.8 76.1 118.3 356.9 423.6 15.6 19.4 30.6 164.9 20.1 136.8 379.0 41.5 298.1 CD84 "hCD84, mCD84, SLAMF5" ENSG00000066294 "CD84 molecule" Q9UIB8 1 160541095-160579516 "CD markers, Predicted membrane proteins" "Adaptive immunity, Autophagy, Cell adhesion, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 24.2" "Cell type enhanced" "Detected in many" "granulocytes: 187.1;Hofbauer cells: 91.1;Kupffer cells: 177.0;Macrophages: 90.6;monocytes: 76.4;T-cells: 46.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 23.8;HEL: 45.3;HL-60: 13.1;HMC-1: 49.7;MOLT-4: 12.9;U-698: 30.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA063316, HPA068020, HPA070502" Enhanced Enhanced "Vesicles,Plasma membrane" NA NA 35000000 "Cluster 46: Basophils - DNA binding" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Vesicles "HPA063316: , HPA068020: , HPA070502: AB_2686274" "unprognostic (4.38e-2)" "unprognostic (6.16e-3)" "unprognostic (1.00e-2)" "unprognostic (8.16e-2)" "unprognostic (2.35e-1)" "unprognostic (2.00e-2)" "unprognostic (3.84e-1)" "unprognostic (2.54e-2)" "unprognostic (8.60e-2)" "unprognostic (1.80e-1)" "unprognostic (8.26e-2)" "unprognostic (1.57e-1)" "unprognostic (1.30e-2)" "unprognostic (2.15e-1)" "unprognostic (4.14e-2)" "unprognostic (1.24e-1)" "unprognostic (1.08e-1)" 3.3 2.4 1.9 19.4 2.1 7.9 2.7 2.3 2.4 2.8 1.9 3.2 2.4 1.4 0.9 2.2 1.1 6.2 1.4 1.7 1.9 0.8 5.2 7.8 24.2 5.2 3.1 1.5 2.0 0.9 0.4 7.1 4.5 1.1 4.5 0.2 1.4 3.4 0.4 1.3 4.6 4.0 3.8 15.2 3.6 1.9 5.2 9.9 1.1 0.7 13.2 4.7 0.8 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 45.3 0.1 0.0 0.0 13.1 49.7 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.9 0.1 0.0 0.0 12.9 9.7 0.0 0.0 0.0 0.4 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 30.8 0.0 2.9 0.0 32.7 9.6 15.0 8.2 8.0 6.5 6.3 7.0 10.1 7.1 6.0 4.0 7.4 1.2 1.4 3.2 4.1 10.5 8.8 1.9 2.1 2.3 2.4 1.7 1.9 5.2 3.1 4.5 3.8 5.2 7.2 1.3 0.0 6.4 0.0 27.4 2.4 0.7 0.0 0.6 0.2 0.6 1.5 1.2 2.8 1.3 0.0 0.0 0.5 20.5 0.2 0.0 0.1 0.9 0.5 0.2 4.2 0.0 21.5 0.1 0.2 0.5 1.2 2.6 0.2 187.1 0.1 3.3 1.1 91.1 0.0 0.2 0.1 0.0 177.0 42.2 1.5 0.6 90.6 5.4 34.7 76.4 0.0 4.1 0.0 0.1 0.0 0.0 0.0 10.8 0.9 0.3 0.3 0.7 0.2 0.0 1.6 1.5 0.1 0.4 0.5 2.4 1.0 46.8 2.9 0.2 0.6 CD86 "B7-2, B7.2, CD28LG2" ENSG00000114013 "CD86 molecule" P42081 3 122055362-122121139 "CD markers, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Host cell receptor for virus entry, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 34.5" "Cell type enhanced" "Detected in many" "Hofbauer cells: 121.3;Kupffer cells: 107.8;Langerhans cells: 148.3;Macrophages: 151.8;Microglial cells: 78.7;monocytes: 489.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "classical monocyte: 79.9;intermediate monocyte: 79.0;memory B-cell: 41.0;myeloid DC: 78.8;naive B-cell: 28.5;non-classical monocyte: 85.2" "Group enriched" "Detected in many" 18 "B-cells: 41.0;dendritic cells: 78.8;monocytes: 85.2" "Cell line enriched" "Detected in some" 7 "HDLM-2: 296.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB004319, HPA026802" Approved Supported "Plasma membrane,Centriolar satellite" NA NA 160000 "Cluster 7: Monocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" "Centriolar satellite" "CAB004319: AB_627200, HPA026802: " "unprognostic (1.81e-1)" "unprognostic (3.78e-3)" "unprognostic (3.04e-2)" "unprognostic (3.52e-2)" "unprognostic (1.36e-1)" "unprognostic (2.79e-1)" "unprognostic (1.15e-1)" "unprognostic (8.56e-2)" "unprognostic (7.72e-3)" "unprognostic (1.21e-1)" "unprognostic (1.28e-1)" "unprognostic (1.98e-1)" "prognostic unfavorable (9.83e-5)" "unprognostic (9.72e-2)" "unprognostic (1.70e-2)" "unprognostic (9.78e-2)" "unprognostic (8.67e-2)" 7.8 5.3 3.5 34.5 3.4 10.3 4.4 4.0 3.6 3.5 4.8 6.3 3.7 2.4 1.0 4.0 2.1 14.3 2.7 3.2 6.1 1.9 11.2 18.6 28.8 7.2 5.5 2.1 2.6 2.9 1.1 15.0 7.0 2.4 7.7 0.9 2.3 2.5 0.8 2.0 6.8 7.4 5.3 23.4 5.2 3.1 5.0 10.6 1.3 0.8 22.0 14.9 1.0 10.2 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 296.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 2.5 0.2 0.0 0.0 0.2 0.0 32.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.4 0.4 0.0 0.1 0.0 0.1 15.1 0.6 35.1 0.0 0.9 0.0 0.1 79.9 0.8 0.0 79.0 0.0 41.0 0.2 0.3 78.8 28.5 0.2 0.1 0.9 3.7 85.2 8.3 1.6 33.4 3.5 3.4 4.0 3.6 3.2 6.1 7.2 5.5 7.0 5.3 5.0 10.2 0.9 0.0 7.7 0.3 36.5 3.6 0.1 1.3 0.0 0.0 0.4 1.3 0.3 1.5 3.2 1.8 0.0 1.8 3.3 0.0 0.0 0.2 3.7 0.1 0.0 2.6 0.0 1.3 0.2 3.5 0.8 0.8 0.5 0.0 2.5 0.1 1.8 0.8 121.3 0.0 0.3 0.0 0.0 107.8 148.3 2.7 0.0 151.8 7.2 78.7 489.4 0.0 0.0 0.5 0.1 0.3 0.0 0.0 20.6 0.3 0.0 0.1 0.1 0.4 0.0 0.3 0.7 0.2 0.3 0.2 4.0 1.9 2.1 0.1 0.0 0.3 CD93 "C1qR(P), C1QR1, C1qRP, CDw93, dJ737E23.1, ECSM3, MXRA4" ENSG00000125810 "CD93 molecule" Q9NPY3 20 23079360-23086324 "CD markers, Plasma proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 137.6" "Cell type enhanced" "Detected in many" "Adipocytes: 321.5;Endothelial cells: 309.2;Hepatic stellate cells: 162.8;Kupffer cells: 156.4;Macrophages: 102.4;monocytes: 131.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 15 "classical monocyte: 25.8;intermediate monocyte: 16.8;myeloid DC: 9.1;neutrophil: 27.8;non-classical monocyte: 7.5" "Group enriched" "Detected in many" 41 "dendritic cells: 9.1;granulocytes: 27.8;monocytes: 25.8" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 346.0;TIME: 442.2;U-937: 593.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA009300, HPA012368" Enhanced Approved "Vesicles,Plasma membrane" NA NA 550000000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 32: U-937 - Innate immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA009300: AB_1846342, HPA012368: AB_1846341" "unprognostic (2.05e-1)" "unprognostic (2.85e-1)" "unprognostic (1.07e-1)" "unprognostic (4.83e-2)" "unprognostic (2.31e-1)" "unprognostic (2.66e-2)" "unprognostic (6.45e-2)" "unprognostic (2.77e-1)" "unprognostic (4.51e-1)" "unprognostic (3.74e-2)" "unprognostic (2.61e-1)" "unprognostic (1.81e-1)" "prognostic unfavorable (2.74e-4)" "unprognostic (8.81e-3)" "unprognostic (6.13e-2)" "unprognostic (4.49e-2)" "unprognostic (3.11e-2)" 81.4 11.9 2.7 43.5 2.6 16.4 41.0 2.8 6.5 23.9 6.5 13.8 9.8 17.8 6.1 19.0 23.4 39.7 34.3 2.7 3.5 25.6 16.3 64.6 14.0 5.4 4.3 6.2 13.2 10.8 6.6 137.6 5.4 11.3 12.1 1.4 9.7 10.9 24.2 12.2 14.5 43.5 4.0 23.4 13.0 4.6 7.1 9.3 21.4 34.4 10.6 41.3 12.8 3.5 0.2 0.0 4.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 346.0 0.0 0.9 0.0 0.0 0.0 0.0 13.1 0.0 0.0 0.0 0.9 0.2 27.8 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 105.3 442.2 0.0 0.1 0.1 0.5 0.0 0.0 0.3 0.0 593.5 0.1 0.0 25.8 0.4 0.3 16.8 0.0 0.0 0.2 0.1 9.1 0.0 0.0 0.0 27.8 0.1 7.5 1.2 0.5 9.9 2.7 2.6 2.8 6.5 2.7 3.5 5.4 4.3 5.4 4.0 7.1 3.5 321.5 3.2 7.4 0.0 2.4 15.0 1.0 0.0 6.2 0.0 1.0 1.8 14.3 5.7 3.7 0.0 0.0 0.2 5.0 0.0 0.0 0.5 0.4 0.4 0.7 309.2 0.0 1.3 0.0 0.0 0.5 9.8 0.5 0.4 5.1 0.0 162.8 1.9 19.9 0.0 0.2 0.0 0.0 156.4 52.5 0.8 1.8 102.4 8.8 4.7 131.8 0.2 6.2 0.0 0.1 0.1 0.0 27.8 2.1 4.1 0.0 0.3 3.0 0.1 19.7 5.7 8.0 0.0 0.2 1.6 10.1 0.4 2.4 3.0 0.0 4.0 CDAN1 "CDA-I, CDAI" ENSG00000140326 "Codanin 1" Q8IWY9 15 42723544-42737128 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Congenital dyserythropoietic anemia, Disease variant, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Sertoli cells: 19.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039404, HPA040787" Supported Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 1: K-562 - Erythropoiesis" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA039404: AB_10673530, HPA040787: AB_2677137" "unprognostic (1.11e-1)" "unprognostic (1.24e-1)" "unprognostic (5.79e-3)" "unprognostic (1.24e-1)" "unprognostic (2.10e-1)" "unprognostic (7.71e-2)" "prognostic unfavorable (1.07e-4)" "unprognostic (7.17e-2)" "unprognostic (9.82e-2)" "unprognostic (1.24e-1)" "unprognostic (2.95e-2)" "unprognostic (1.26e-1)" "unprognostic (4.35e-3)" "unprognostic (2.05e-1)" "unprognostic (1.16e-1)" "unprognostic (9.20e-3)" "unprognostic (2.04e-1)" 4.0 5.0 2.1 3.6 2.2 8.1 4.3 4.3 3.1 7.7 3.2 4.5 2.8 5.9 4.4 4.1 6.1 2.5 2.9 2.1 0.9 3.2 4.0 3.5 4.2 3.0 1.5 11.3 4.8 3.5 5.1 3.2 2.7 6.9 2.5 2.6 5.4 3.5 4.2 4.9 4.2 2.8 0.7 4.6 4.5 6.3 1.4 5.2 5.1 2.8 3.4 5.8 5.6 2.6 8.1 5.4 7.2 10.4 6.3 5.4 8.6 10.4 4.3 9.9 7.2 13.6 4.2 3.9 11.2 5.8 9.7 15.5 7.7 4.7 2.9 9.9 7.2 14.5 10.3 5.3 4.7 10.8 13.2 7.4 5.2 6.3 4.5 6.1 7.6 13.0 18.9 5.7 8.2 4.5 8.4 14.2 3.6 7.7 8.5 11.9 9.0 3.4 3.1 7.9 5.9 6.8 8.2 11.3 1.7 4.6 8.6 15.9 5.6 10.4 9.2 8.6 12.1 11.2 12.7 8.7 5.4 15.8 8.6 1.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 2.1 2.2 4.3 3.1 2.1 0.9 3.0 1.5 2.7 0.7 1.4 2.6 2.0 0.0 3.7 4.6 2.4 1.9 2.0 1.5 1.8 3.3 3.2 1.8 2.2 2.8 1.5 7.3 4.2 3.0 2.6 1.9 0.0 1.5 0.4 2.0 2.8 2.3 4.8 1.7 7.6 1.8 1.6 2.9 3.6 2.0 1.3 9.0 3.9 3.6 2.1 1.7 6.3 1.6 4.1 2.5 0.9 1.2 4.4 1.6 0.0 4.7 1.5 4.5 2.1 5.5 3.8 1.6 0.5 4.9 2.5 2.3 2.2 1.3 1.9 4.7 19.7 3.4 2.4 5.4 2.1 2.8 1.3 2.2 2.5 4.6 2.6 1.7 CDC42EP3 "BORG2, CEP3, UB1" ENSG00000163171 "CDC42 effector protein 3" Q9UKI2 2 37641882-37738468 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 233.5;Langerhans cells: 259.6;Melanocytes: 200.9" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebral cortex: 24.8" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "LHCN-M2: 607.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034986, HPA061792" Approved Supported "Plasma membrane,Actin filaments" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA034986: AB_10602207, HPA061792: AB_2732670" "unprognostic (1.13e-1)" "unprognostic (1.60e-1)" "unprognostic (3.92e-2)" "unprognostic (4.11e-3)" "unprognostic (2.38e-2)" "unprognostic (2.72e-3)" "unprognostic (1.41e-1)" "unprognostic (5.76e-2)" "unprognostic (2.68e-1)" "unprognostic (1.72e-1)" "unprognostic (1.84e-1)" "unprognostic (3.81e-1)" "unprognostic (3.14e-3)" "unprognostic (7.30e-3)" "unprognostic (1.97e-1)" "unprognostic (2.97e-1)" "unprognostic (4.53e-2)" 55.2 10.3 4.4 21.9 5.4 86.5 38.8 0.4 24.8 50.5 22.2 42.4 6.1 92.7 10.7 21.1 24.3 21.2 59.6 7.2 6.9 24.4 9.0 29.3 25.5 2.8 3.9 23.8 27.2 8.3 6.8 26.3 5.9 93.4 20.6 15.4 14.6 107.0 57.7 15.1 17.3 96.4 2.2 26.8 14.4 41.9 5.5 36.2 15.9 22.0 23.4 45.4 20.3 3.3 100.2 38.0 21.6 1.2 80.6 42.2 33.8 84.2 221.1 127.5 92.2 69.8 39.3 17.6 66.5 198.9 39.2 47.1 27.1 99.6 129.4 68.2 9.5 31.6 37.5 0.0 156.1 7.1 1.8 129.6 91.7 110.1 243.2 206.6 75.6 7.0 5.0 13.8 607.0 0.8 3.4 59.3 44.1 1.2 23.5 2.8 163.8 9.3 93.1 47.4 23.7 69.9 41.6 29.7 50.2 37.7 9.9 58.8 57.5 152.3 40.0 40.2 86.9 27.0 37.9 5.9 63.1 48.4 215.4 54.6 88.2 6.9 69.4 56.7 74.6 24.9 44.5 60.2 30.9 11.0 14.3 37.3 189.4 38.3 119.5 0.9 35.8 61.5 4.4 5.4 0.4 24.8 7.2 6.9 2.8 3.9 5.9 2.2 5.5 3.3 233.5 6.4 50.4 1.6 50.3 37.1 137.3 81.4 5.7 12.3 31.9 40.1 97.5 12.8 28.9 31.3 35.5 30.8 63.8 7.8 9.8 20.8 51.7 49.6 24.4 113.9 41.2 14.5 15.6 15.9 68.2 29.7 14.3 33.6 129.6 9.2 83.2 1.5 12.2 101.0 34.9 59.6 32.6 44.1 259.6 158.0 15.2 86.0 200.9 9.4 78.6 27.5 106.1 4.0 0.5 24.9 3.0 126.7 43.4 32.7 1.1 5.0 73.3 13.2 0.0 29.2 29.4 67.2 13.6 3.1 13.5 12.0 97.7 1.4 6.0 38.5 CDH15 "CDH14, CDH3" ENSG00000129910 "Cadherin 15" P55291 16 89171748-89195492 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Cell adhesion" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 8 "brain: 24.4;skeletal muscle: 57.0" "Cell type enriched" "Detected in some" 13 "Skeletal myocytes: 76.1" "Low cancer specificity" "Detected in some" "Region enriched" "Detected in some" 15 "cerebellum: 24.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RH-30: 145.8" "Region enriched" "Detected in many" 7 "cerebellum: 15.7" "Region enriched" "Detected in some" 17 "cerebellum: 18.7" "HPA009139, HPA070961" Enhanced Supported Enhanced "Golgi apparatus,Plasma membrane" NA NA 870000 "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 50: Fibroblasts - ECM organization" "Golgi apparatus, Plasma membrane" "HPA009139: AB_1078372, HPA070961: AB_2686328" "unprognostic (1.26e-1)" "unprognostic (7.70e-3)" "unprognostic (6.64e-3)" "unprognostic (2.81e-1)" "unprognostic (7.79e-3)" "unprognostic (2.70e-3)" "unprognostic (2.84e-3)" "unprognostic (4.37e-2)" "unprognostic (2.30e-3)" "unprognostic (7.66e-2)" "unprognostic (4.05e-2)" "unprognostic (1.73e-1)" "unprognostic (1.14e-7)" "unprognostic (3.09e-2)" "unprognostic (3.13e-1)" "unprognostic (5.50e-2)" "unprognostic (2.64e-2)" 0.0 0.2 0.1 0.0 0.2 0.0 0.0 24.4 0.8 1.3 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.1 0.1 1.3 0.4 0.0 0.1 0.8 0.2 1.4 0.0 0.1 0.7 1.6 0.4 0.0 0.0 0.9 0.0 57.0 0.1 0.0 0.0 0.3 1.2 0.2 0.6 0.1 0.0 0.0 5.3 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 1.8 0.7 0.0 0.1 4.7 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 31.5 0.1 0.0 0.1 0.0 0.2 0.3 0.0 145.8 0.3 0.0 0.0 0.8 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 24.4 0.8 0.0 0.1 0.1 0.8 1.6 0.3 0.1 0.6 0.2 0.0 2.0 0.0 0.7 0.0 0.2 0.0 0.0 0.1 0.1 0.4 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.0 0.1 1.0 0.1 1.2 0.0 0.1 0.0 0.3 0.7 0.9 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.8 0.0 0.2 1.8 0.0 0.0 1.5 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.2 0.0 0.2 0.0 76.1 0.4 1.5 5.5 0.0 0.0 0.1 0.2 0.8 0.1 0.1 CDH2 "CD325, CDHN, NCAD" ENSG00000170558 "Cadherin 2" P19022 18 27932879-28177946 "CD markers, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 196.0" "Cell type enhanced" "Detected in many" "Astrocytes: 217.7;Cardiomyocytes: 368.8;Excitatory neurons: 311.2;Granulosa cells: 312.5;Inhibitory neurons: 198.2;Muller glia cells: 157.9;Oligodendrocyte precursor cells: 267.9" "Cancer enhanced" "Detected in all" "glioma: 39.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "basophil: 1.7;neutrophil: 1.3" "Lineage enriched" "Detected in single" 6 "granulocytes: 1.7" "Cell line enhanced" "Detected in many" "AF22: 278.2;BJ: 230.7;fHDF/TERT166: 459.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000141, CAB018580, HPA058574, CAB078686" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 160000000 "Cluster 10: Basophils - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB000141: , CAB018580: AB_626778, CAB078686: AB_2665849, HPA058574: AB_2683760" "unprognostic (9.42e-2)" "unprognostic (2.69e-3)" "unprognostic (9.07e-3)" "unprognostic (5.45e-2)" "unprognostic (1.14e-1)" "unprognostic (9.30e-2)" "unprognostic (3.97e-2)" "unprognostic (2.53e-3)" "unprognostic (6.70e-3)" "unprognostic (1.00e-2)" "unprognostic (7.53e-2)" "unprognostic (3.51e-2)" "unprognostic (3.02e-2)" "unprognostic (1.93e-3)" "unprognostic (6.69e-2)" "unprognostic (1.33e-1)" "unprognostic (2.59e-3)" 0.6 66.5 27.4 2.6 29.0 0.2 0.3 20.6 31.6 6.6 7.9 4.8 0.8 6.2 1.1 0.4 10.5 3.1 196.0 30.0 31.6 18.1 57.2 1.0 1.9 21.7 26.3 6.7 0.9 29.8 8.1 0.4 20.1 2.4 1.1 60.3 0.4 10.8 0.4 0.3 1.4 6.8 24.1 13.5 5.9 44.4 33.3 3.8 6.2 2.2 1.6 1.1 2.7 22.7 0.3 25.8 278.2 0.3 48.1 7.8 0.2 230.7 72.0 94.9 80.8 0.1 0.4 0.0 128.3 459.1 46.0 36.7 50.0 0.2 130.4 0.4 35.8 0.0 66.8 86.7 48.0 0.0 0.1 4.6 0.4 198.6 37.4 212.9 84.0 15.4 0.0 0.1 77.8 0.0 59.4 0.1 43.8 0.1 30.5 0.2 37.1 45.6 0.1 9.9 83.4 144.4 0.1 0.2 26.8 116.8 0.3 0.5 11.6 206.6 63.6 2.9 181.6 0.2 0.3 0.3 40.6 0.2 163.0 1.7 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.3 0.0 0.0 0.0 0.0 27.4 29.0 20.6 31.6 30.0 31.6 21.7 26.3 20.1 24.1 33.3 22.7 0.8 0.0 0.6 217.7 1.2 0.3 0.0 3.4 0.0 38.7 1.6 0.4 368.8 67.2 1.2 11.0 150.1 0.1 0.0 0.0 0.0 12.9 53.2 1.4 15.2 9.8 0.0 6.1 311.2 0.4 0.0 16.7 0.0 2.6 0.0 312.5 12.5 125.3 0.3 3.3 198.2 0.0 2.0 2.2 0.4 17.7 2.1 1.2 3.6 106.8 0.1 157.9 0.0 267.9 138.6 19.2 0.0 12.8 0.0 0.1 0.0 47.5 1.7 99.9 6.6 0.4 45.8 4.8 24.1 0.0 0.0 0.3 0.6 1.6 0.0 0.1 CDH26 VR20 ENSG00000124215 "Cadherin 26" Q8IXH8 20 59958423-60034011 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 8.0" "Cell type enhanced" "Detected in many" "Astrocytes: 17.9;Club cells: 18.7;Oligodendrocytes: 14.9;Respiratory ciliated cells: 39.6;Syncytiotrophoblasts: 14.9" "Group enriched" "Detected in some" 6 "cervical cancer: 1.5;head and neck cancer: 0.9;lung cancer: 2.3;prostate cancer: 3.6;urothelial cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 36.4" "Low region specificity" "Detected in some" "HPA015722, HPA047578" Uncertain Supported "Plasma membrane,Microtubules" NA NA "Cluster 27: Brain & Skin - Unknown function" "Cluster 15: RT4 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" Microtubules "HPA015722: AB_2077659, HPA047578: AB_2680091" "unprognostic (2.42e-1)" "prognostic favorable (7.62e-4)" "unprognostic (4.71e-4)" "unprognostic (8.17e-2)" "unprognostic (9.40e-2)" "unprognostic (9.95e-3)" "unprognostic (6.65e-2)" "prognostic favorable (3.75e-4)" "unprognostic (1.37e-1)" "unprognostic (1.69e-1)" "unprognostic (3.26e-4)" "unprognostic (8.24e-3)" "unprognostic (9.96e-7)" "unprognostic (1.85e-2)" "unprognostic (2.73e-1)" "unprognostic (2.54e-2)" "unprognostic (1.04e-1)" 0.9 0.4 1.0 0.3 1.5 1.0 0.8 1.2 2.0 2.0 0.3 0.7 0.4 0.6 0.4 3.4 2.0 0.4 0.7 0.9 1.8 0.5 0.3 2.1 0.4 1.6 1.7 0.3 0.5 0.3 1.7 0.4 1.5 8.0 0.3 0.4 2.0 0.5 1.0 0.6 0.8 0.4 0.6 0.8 1.2 0.7 1.9 0.9 0.6 0.3 3.0 2.7 1.3 2.6 0.0 0.7 0.2 0.0 0.6 0.2 0.4 0.2 0.0 0.1 0.0 0.8 0.8 0.1 0.5 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.1 7.9 0.1 0.1 0.0 0.3 0.3 0.1 1.1 0.1 0.0 0.0 0.0 0.4 0.0 0.3 0.3 0.3 0.3 0.4 0.4 0.0 0.1 0.0 0.0 0.7 0.1 36.4 0.8 0.1 0.4 0.2 0.1 0.4 0.2 0.4 0.2 0.0 0.0 1.0 0.0 0.3 0.2 0.0 0.0 1.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 1.5 1.2 2.0 0.9 1.8 1.6 1.7 1.5 0.6 1.9 2.6 4.3 6.4 6.1 17.9 0.1 0.1 1.2 6.6 0.0 0.5 1.6 0.5 0.7 0.0 18.7 0.0 0.0 1.7 0.0 0.2 0.0 0.0 3.2 2.1 0.4 2.1 0.0 2.5 9.3 0.0 0.0 0.3 0.0 0.4 1.3 0.0 0.7 0.1 0.6 0.0 8.4 0.0 6.1 1.3 0.4 1.7 0.0 1.4 0.0 7.5 0.6 0.2 1.0 7.1 14.9 0.0 0.0 0.0 0.4 10.9 0.2 0.1 39.6 0.0 0.0 0.5 2.4 0.9 0.2 0.2 0.0 14.9 0.2 0.1 0.2 7.4 CDH3 "CDHP, PCAD" ENSG00000062038 "Cadherin 3" P22223 16 68636189-68727468 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Ectodermal dysplasia, Hypotrichosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 47.1;ovary: 32.7" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 60.8;Basal prostatic cells: 67.2;Basal respiratory cells: 161.4;Basal squamous epithelial cells: 71.7;Granulosa cells: 77.6;Melanocytes: 60.5;Pancreatic endocrine cells: 85.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 100.6;HaCaT: 263.9;HBEC3-KT: 126.9;hTCEpi: 94.3;hTERT-HME1: 72.7;RPTEC TERT1: 116.8" "Region enhanced" "Detected in single" "olfactory bulb: 1.7" "Low region specificity" "Detected in all" "HPA001767, CAB002487" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 510000 "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane" "Cell Junctions" "CAB002487: AB_563446, HPA001767: AB_1078376" "unprognostic (1.55e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-1)" "unprognostic (4.38e-3)" "unprognostic (6.73e-2)" "unprognostic (1.55e-2)" "unprognostic (1.85e-2)" "prognostic unfavorable (8.53e-4)" "unprognostic (1.22e-1)" "unprognostic (3.45e-2)" "prognostic unfavorable (8.43e-4)" "unprognostic (4.30e-2)" "unprognostic (2.41e-5)" "unprognostic (2.11e-1)" "unprognostic (1.09e-1)" "unprognostic (1.33e-3)" "unprognostic (8.56e-2)" 3.6 0.2 1.3 3.4 1.5 0.1 8.2 1.9 1.6 9.7 47.1 0.4 0.5 10.0 8.8 26.8 12.0 1.5 0.3 3.5 0.8 6.0 0.0 2.0 2.5 1.2 1.0 32.7 0.6 1.5 4.4 4.5 0.6 13.6 0.7 0.8 12.4 4.6 0.2 25.8 0.7 4.0 1.9 10.9 1.0 1.6 1.1 18.8 1.2 0.0 11.7 3.9 11.2 1.1 100.6 0.2 0.9 0.1 0.1 0.0 8.6 0.0 0.0 0.3 0.1 61.4 36.6 0.0 0.4 0.0 0.2 263.9 2.6 126.9 0.4 0.0 1.2 0.0 0.2 0.0 0.2 0.2 0.5 0.0 94.3 0.1 72.7 0.3 0.0 0.0 0.0 0.2 0.0 48.8 0.1 0.1 5.3 0.9 8.8 0.0 0.0 0.0 116.8 44.5 0.5 0.2 0.8 0.0 50.0 45.6 29.2 0.2 0.0 0.0 0.2 0.0 0.3 0.1 0.2 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.3 1.5 1.9 1.6 3.5 0.8 1.2 1.0 0.6 1.9 1.1 1.1 0.2 16.0 4.6 0.7 0.0 60.8 67.2 161.4 71.7 1.2 6.8 39.2 1.4 0.0 35.9 14.7 2.1 23.4 0.5 0.5 0.0 35.7 0.5 0.9 8.2 1.3 1.2 0.0 6.0 32.1 2.1 3.7 0.0 0.9 1.3 77.6 0.0 0.0 2.8 0.0 9.1 1.5 20.3 0.0 1.9 0.2 0.6 0.7 60.5 0.0 1.0 0.4 1.0 3.0 2.2 85.7 0.1 9.4 1.2 44.5 0.0 0.1 12.6 0.5 0.0 0.6 5.9 0.4 1.0 26.5 30.7 6.3 1.2 0.1 1.5 43.1 CDH6 ENSG00000113361 "Cadherin 6" P55285 5 31193686-31329146 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 14.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 48.6;Excitatory neurons: 67.1;Oligodendrocyte precursor cells: 60.8;Pancreatic endocrine cells: 63.8;Proximal tubular cells: 171.1;Sertoli cells: 46.0;Smooth muscle cells: 69.5" "Group enriched" "Detected in many" 5 "ovarian cancer: 15.0;renal cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "EFO-21: 477.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA007047, HPA007403, HPA007456, CAB025274" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 9600000 "Cluster 21: Non-specific - Transcription" "Cluster 38: EFO-21 - Unknown function" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cell Junctions" "CAB025274: , HPA007047: AB_1078374, HPA007403: , HPA007456: AB_1078373" "unprognostic (3.87e-2)" "unprognostic (4.69e-2)" "unprognostic (1.35e-1)" "unprognostic (1.92e-3)" "unprognostic (1.58e-2)" "unprognostic (7.61e-3)" "unprognostic (9.04e-2)" "unprognostic (2.68e-1)" "unprognostic (2.74e-2)" "unprognostic (5.22e-2)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (8.29e-3)" "unprognostic (1.22e-3)" "unprognostic (2.67e-1)" "unprognostic (6.22e-2)" "unprognostic (2.09e-2)" 5.0 1.1 3.2 1.4 9.3 0.2 2.6 2.2 3.7 4.3 0.5 1.3 1.3 2.3 1.8 2.4 6.8 9.2 2.0 2.2 7.4 14.8 0.7 4.5 0.6 4.9 9.5 0.7 0.7 1.1 1.0 3.6 6.0 1.1 0.9 1.5 0.7 1.8 1.2 1.0 1.2 2.6 3.2 0.8 1.0 0.3 9.8 0.4 2.3 1.6 0.7 2.3 1.9 3.9 0.1 1.9 62.2 0.0 0.0 0.0 0.2 1.5 0.1 0.0 0.0 0.2 0.0 0.1 477.1 0.3 0.0 0.0 49.6 0.1 0.0 0.6 0.0 0.1 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.2 17.5 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.1 9.4 0.0 0.2 0.0 10.9 0.1 14.0 0.0 1.8 0.0 0.0 0.1 0.2 19.3 0.1 0.2 0.0 0.1 1.8 5.9 1.5 0.1 0.4 1.1 0.1 0.1 1.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 3.2 9.3 2.2 3.7 2.2 7.4 4.9 9.5 6.0 3.2 9.8 3.9 5.7 0.0 0.5 7.2 2.4 0.9 0.1 36.5 0.0 10.8 0.1 0.4 3.1 48.6 7.0 11.0 0.0 0.0 0.0 0.0 27.4 37.2 0.2 2.9 0.6 5.3 0.0 0.0 67.1 3.0 0.0 2.9 0.0 2.9 0.0 4.1 0.0 0.1 0.1 0.0 33.6 0.0 0.0 0.0 2.5 0.1 0.3 1.3 0.0 39.4 1.0 0.3 0.0 60.8 5.5 63.8 0.0 0.4 0.0 1.2 0.0 171.1 1.1 0.8 46.0 0.6 69.5 0.0 0.4 0.1 1.0 0.0 1.8 0.2 0.0 0.1 CEACAM7 "CEA, CGM2" ENSG00000007306 "CEA cell adhesion molecule 7" Q14002 19 41673303-41706976 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 651.8" "Group enriched" "Detected in some" 9 "Distal enterocytes: 1454.0;Paneth cells: 731.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 66.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA069621, HPA073910" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 37: Intestine - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "HPA069621: AB_2686162, HPA073910: " "unprognostic (5.24e-2)" "unprognostic (2.72e-1)" "unprognostic (1.64e-2)" "unprognostic (6.03e-2)" "unprognostic (2.07e-2)" "unprognostic (4.30e-2)" "unprognostic (3.61e-2)" "unprognostic (1.74e-1)" "unprognostic (4.66e-2)" "unprognostic (1.86e-1)" "unprognostic (3.14e-1)" 0.6 0.0 0.0 71.4 0.0 0.1 2.9 0.0 0.0 13.3 0.0 595.8 0.5 0.3 0.0 52.6 0.6 39.4 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.4 651.8 0.0 4.0 0.8 0.1 1.4 0.7 5.7 0.0 0.2 2.0 0.1 0.0 0.0 0.0 0.0 12.0 23.4 39.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 0.2 0.9 0.0 0.0 0.1 0.0 0.1 0.0 2.8 0.0 0.0 0.0 0.0 1454.0 0.0 116.6 0.1 0.0 0.0 0.5 8.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.0 0.0 0.0 0.0 0.1 1.0 731.2 0.0 0.0 1.4 0.0 0.0 2.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 38.4 30.3 CELSR1 "ADGRC1, CDHF9, FMI2, HFMI2, ME2" ENSG00000075275 "Cadherin EGF LAG seven-pass G-type receptor 1" Q9NYQ6 22 46360834-46537620 "Disease related genes, G-protein coupled receptors, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 31.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Basal respiratory cells: 28.1;Club cells: 31.1;Endometrial ciliated cells: 31.8;Glandular and luminal cells: 42.6;Respiratory ciliated cells: 60.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "memory B-cell: 2.2;naive B-cell: 1.9" "Lineage enriched" "Detected in single" 6 "B-cells: 2.2" "Cell line enhanced" "Detected in many" "A549: 68.4;RPTEC TERT1: 48.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA052976, HPA060521" Enhanced "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 280000 "Cluster 43: B-cells - Humoral immune response" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA052976: AB_2682004, HPA060521: AB_2684303" "unprognostic (5.62e-2)" "unprognostic (4.93e-2)" "unprognostic (4.22e-2)" "unprognostic (1.54e-3)" "unprognostic (2.71e-1)" "unprognostic (1.83e-1)" "unprognostic (3.66e-1)" "unprognostic (3.36e-1)" "unprognostic (5.31e-2)" "unprognostic (1.05e-2)" "unprognostic (1.18e-2)" "unprognostic (8.59e-2)" "unprognostic (2.44e-2)" "unprognostic (1.17e-1)" "unprognostic (2.67e-2)" "unprognostic (1.13e-1)" "unprognostic (1.07e-1)" 0.7 0.8 0.4 3.1 0.9 0.8 7.8 1.5 0.5 9.9 1.2 1.6 0.9 3.7 10.2 11.5 15.4 1.4 3.4 1.0 0.4 17.1 5.2 12.5 5.9 2.4 3.9 0.2 2.6 6.3 2.4 1.0 1.4 5.0 1.8 0.5 12.0 3.9 0.2 31.5 1.6 1.1 1.6 3.3 5.4 1.3 2.2 2.4 3.7 0.1 7.9 3.9 3.7 1.0 22.3 68.4 11.3 10.6 0.0 0.0 6.5 2.3 3.4 2.3 1.3 21.7 21.9 0.2 32.1 1.3 22.0 35.0 7.5 28.7 2.0 0.0 10.2 0.0 25.6 2.0 1.0 3.2 1.8 0.0 43.5 0.0 26.2 31.6 0.4 1.7 0.3 0.4 0.0 38.4 0.1 11.9 4.5 12.1 8.1 0.1 0.1 8.1 48.7 13.5 0.7 0.9 16.1 17.3 3.7 7.9 39.7 16.7 0.9 0.1 0.3 0.0 0.4 10.6 1.1 10.5 15.2 0.1 12.9 0.0 0.0 0.0 0.2 0.1 0.2 2.2 0.1 0.1 0.0 1.9 0.2 0.1 0.0 0.3 0.0 0.1 0.0 0.1 0.4 0.9 1.5 0.5 1.0 0.4 2.4 3.9 1.4 1.6 2.2 1.0 0.5 41.7 23.5 0.0 5.8 17.1 4.1 28.1 8.0 0.2 14.2 5.2 12.7 2.8 31.1 5.5 0.0 1.9 2.3 0.8 0.0 1.8 2.3 31.8 5.0 5.6 1.2 0.0 1.2 0.7 1.9 1.0 2.6 42.6 0.0 0.6 1.8 1.5 2.4 0.0 1.2 2.8 6.1 0.0 4.1 10.3 0.0 1.1 5.4 1.0 1.1 1.1 0.0 0.5 0.7 4.0 0.3 0.0 1.1 4.3 0.0 8.2 60.3 0.3 0.0 0.1 2.8 0.4 0.6 12.6 15.6 0.8 1.1 0.0 1.7 5.1 CEP295 KIAA1731 ENSG00000166004 "Centrosomal protein 295" Q9C0D2 11 93661682-93730358 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 78.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038595, HPA038596, HPA038597" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA038595: AB_2676104, HPA038596: AB_10672720, HPA038597: AB_2676106" "unprognostic (1.35e-2)" "unprognostic (3.08e-1)" "unprognostic (7.66e-2)" "unprognostic (5.56e-2)" "unprognostic (5.73e-2)" "unprognostic (4.08e-3)" "unprognostic (6.03e-3)" "unprognostic (2.14e-1)" "unprognostic (5.54e-3)" "unprognostic (3.73e-2)" "unprognostic (4.99e-4)" "unprognostic (1.34e-1)" "unprognostic (5.29e-3)" "unprognostic (1.46e-2)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (2.18e-2)" 6.6 5.8 7.5 6.3 8.1 16.0 8.3 14.4 10.5 7.6 5.0 8.7 6.2 7.0 7.4 5.8 6.8 5.2 5.3 7.3 6.9 6.2 5.0 6.0 11.1 6.3 5.9 8.3 6.6 4.7 8.4 6.3 6.6 8.3 6.8 14.7 5.5 5.2 5.3 8.9 7.5 5.5 4.9 9.4 6.2 12.0 7.6 10.3 8.7 5.8 7.4 7.7 6.6 10.2 10.5 9.4 23.9 20.4 10.8 10.4 11.6 13.2 9.7 12.2 14.2 17.3 19.2 3.1 19.1 8.3 16.9 18.7 11.8 9.5 12.4 15.0 9.4 19.0 28.2 8.6 6.5 17.1 17.4 7.7 5.6 11.6 10.0 11.5 10.4 16.9 21.6 19.4 15.8 8.8 8.9 28.1 7.5 19.6 9.7 17.7 22.6 12.6 10.1 17.9 13.9 12.9 20.9 13.8 3.7 14.8 22.8 9.4 9.6 11.3 14.8 20.9 10.1 6.9 16.7 20.2 6.7 19.7 15.9 3.3 1.7 3.6 1.5 0.9 1.2 3.2 1.3 1.0 0.8 3.5 1.6 1.4 5.2 1.6 1.3 1.7 1.1 0.4 7.5 8.1 14.4 10.5 7.3 6.9 6.3 5.9 6.6 4.9 7.6 10.2 10.9 9.6 14.3 24.2 14.0 0.0 3.3 0.0 5.2 30.5 7.0 8.9 9.4 5.7 5.6 5.5 27.1 12.8 8.6 2.5 3.9 7.8 78.7 12.4 15.0 9.6 3.6 25.7 41.2 7.8 10.3 8.8 11.2 10.2 16.4 48.8 6.8 4.2 8.0 18.5 40.8 5.5 0.0 7.9 0.0 21.4 12.8 7.7 0.0 15.0 10.3 10.3 10.3 23.6 33.5 5.3 4.1 14.3 12.2 5.6 5.8 4.0 5.1 38.1 6.6 9.4 8.7 48.8 18.6 7.5 0.0 6.6 9.8 15.8 5.8 2.8 CEP57L1 "bA487F23.2, C6orf182, MGC21731" ENSG00000183137 "Centrosomal protein 57 like 1" Q8IYX8 6 109095110-109174418 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 50.3;Spermatocytes: 75.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040378 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA040378: AB_10794028" "unprognostic (5.93e-3)" "unprognostic (4.95e-2)" "unprognostic (1.40e-2)" "unprognostic (2.13e-2)" "unprognostic (1.11e-1)" "unprognostic (3.41e-2)" "unprognostic (4.69e-3)" "unprognostic (3.63e-2)" "unprognostic (7.25e-2)" "unprognostic (1.27e-1)" "unprognostic (2.33e-1)" "unprognostic (9.97e-2)" "unprognostic (2.42e-5)" "unprognostic (2.37e-1)" "unprognostic (2.00e-1)" "unprognostic (8.48e-2)" "unprognostic (1.72e-1)" 10.5 7.6 5.1 7.8 5.9 10.2 10.2 10.8 7.8 8.2 4.6 8.5 8.7 9.3 10.5 6.2 6.0 9.4 7.7 5.8 4.1 8.0 10.0 6.6 8.9 4.9 4.2 6.5 7.5 16.9 5.6 10.1 5.5 6.4 10.9 12.0 5.2 6.3 6.1 6.8 7.8 10.8 3.9 7.7 7.3 26.2 5.5 14.4 8.7 6.6 7.4 6.4 6.5 7.9 17.9 7.9 23.1 22.9 21.2 35.2 18.1 40.3 22.1 35.8 39.8 11.9 15.3 16.0 18.4 20.9 30.8 9.1 16.1 15.4 56.1 20.3 16.1 34.8 18.9 12.3 19.6 28.5 14.5 21.2 11.0 30.3 29.9 19.2 32.4 52.5 63.9 52.5 32.4 11.8 32.0 24.6 7.6 14.7 14.6 25.7 17.4 15.7 17.0 7.4 17.4 14.4 19.8 14.7 12.9 15.0 18.2 43.9 14.7 23.1 13.6 24.4 42.9 15.4 19.1 25.3 21.8 43.1 18.9 15.9 5.2 6.6 4.7 6.1 5.1 3.3 4.8 6.7 5.7 6.3 4.5 6.7 3.6 11.6 9.6 6.0 6.9 4.6 5.1 5.9 10.8 7.8 5.8 4.1 4.9 4.2 5.5 3.9 5.5 7.9 12.9 6.4 5.3 12.4 6.3 3.3 7.6 7.4 7.4 6.6 6.8 7.2 10.3 2.8 6.8 5.5 20.9 9.8 9.7 4.2 7.9 7.0 50.3 12.8 18.5 10.6 5.4 18.1 31.9 5.4 13.2 15.5 8.2 6.9 5.1 20.5 8.2 6.3 10.2 5.0 31.1 3.1 8.2 4.1 6.8 39.3 17.4 7.7 8.8 27.2 7.7 10.4 8.2 26.2 36.1 6.0 4.5 12.4 13.2 4.4 5.7 13.4 9.8 12.3 13.1 21.8 14.1 75.7 13.0 5.8 4.4 8.5 6.7 13.6 6.1 5.0 CEP89 "CCDC123, FLJ14640" ENSG00000121289 "Centrosomal protein 89" Q96ST8 19 32875925-32971991 "Disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039382, HPA040056" Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039382: AB_2676479, HPA040056: AB_10671048" "unprognostic (4.23e-2)" "unprognostic (7.50e-3)" "unprognostic (1.97e-1)" "unprognostic (1.53e-3)" "unprognostic (1.30e-1)" "unprognostic (1.08e-1)" "prognostic unfavorable (8.78e-5)" "unprognostic (1.12e-1)" "unprognostic (4.55e-2)" "unprognostic (3.04e-2)" "unprognostic (1.80e-2)" "unprognostic (4.00e-2)" "unprognostic (1.74e-1)" "unprognostic (4.48e-2)" "unprognostic (6.53e-2)" "unprognostic (3.03e-1)" "unprognostic (2.47e-2)" 6.0 6.0 6.3 5.3 6.7 4.7 6.4 7.7 6.4 9.1 7.7 8.9 4.0 9.8 6.7 6.3 8.9 5.1 6.2 6.6 6.9 8.6 3.3 5.7 6.0 5.8 5.6 10.1 6.1 7.0 9.3 5.3 4.7 12.5 4.4 7.4 6.7 5.9 5.9 6.6 6.7 6.9 4.0 6.4 6.2 4.2 7.3 6.2 7.5 4.3 4.3 8.0 6.8 6.0 19.1 25.7 17.1 14.7 9.1 11.0 9.9 14.7 9.8 25.5 19.4 9.3 11.2 7.6 7.8 15.1 14.4 10.5 16.9 11.9 17.6 20.2 10.4 5.9 18.5 8.9 7.2 8.3 5.7 13.3 16.2 24.1 16.2 10.4 19.5 10.4 9.2 11.0 12.3 14.2 9.4 6.4 7.3 10.4 8.0 10.4 9.2 6.6 11.9 10.3 24.1 17.7 15.1 10.3 8.8 10.3 7.7 6.7 12.6 18.4 16.1 16.0 15.3 5.3 9.1 7.0 15.8 7.8 14.0 12.8 3.1 1.6 2.7 4.6 4.9 3.3 2.9 2.4 1.8 5.7 2.8 3.3 3.7 2.1 2.4 3.7 3.4 1.7 6.3 6.7 7.7 6.4 6.6 6.9 5.8 5.6 4.7 4.0 7.3 6.0 12.7 28.9 16.0 17.3 9.5 5.1 11.5 14.5 8.0 16.3 11.7 11.8 17.5 10.0 19.0 20.2 18.8 9.3 9.6 8.0 11.7 19.1 15.1 49.2 24.9 14.8 9.7 13.3 17.2 16.6 11.2 17.7 10.7 17.3 17.1 21.1 14.6 5.6 11.8 20.2 13.6 9.7 8.2 5.3 5.1 8.5 16.1 8.9 5.4 14.0 9.8 9.6 10.3 9.5 15.9 15.1 5.2 12.8 5.4 6.7 9.9 16.3 48.3 38.6 0.0 17.5 16.1 20.3 13.8 7.5 4.5 4.2 9.0 12.7 8.6 6.6 CFAP157 C9orf117 ENSG00000160401 "Cilia and flagella associated protein 157" Q5JU67 9 127706988-127716002 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 18.6;choroid plexus: 35.9;fallopian tube: 59.5" "Group enriched" "Detected in some" 4 "Early spermatids: 56.8;Endometrial ciliated cells: 153.5;Late spermatids: 85.0;Respiratory ciliated cells: 189.5" "Cancer enhanced" "Detected in many" "endometrial cancer: 4.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 7.3;HeLa: 6.2" "Low region specificity" "Detected in some" "Not detected" "Not detected" "HPA021474, HPA021786" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA021474: AB_1845801, HPA021786: AB_1845802" "unprognostic (1.69e-1)" "unprognostic (2.80e-2)" "unprognostic (2.41e-2)" "prognostic favorable (1.45e-4)" "unprognostic (3.02e-1)" "unprognostic (1.58e-1)" "unprognostic (4.71e-3)" "unprognostic (1.49e-1)" "unprognostic (3.14e-4)" "unprognostic (7.72e-2)" "unprognostic (4.93e-4)" "unprognostic (9.32e-3)" "unprognostic (4.95e-3)" "unprognostic (5.71e-4)" "unprognostic (4.34e-2)" "unprognostic (7.38e-2)" "unprognostic (1.28e-1)" 0.2 0.3 2.4 0.1 1.4 0.1 0.2 0.8 0.4 9.1 35.9 0.1 0.0 1.1 1.8 0.8 59.5 0.6 0.3 3.2 3.3 0.5 0.1 11.2 0.4 12.6 18.6 0.4 1.1 0.2 4.7 0.2 7.2 0.3 0.0 0.1 0.5 0.2 0.3 0.6 0.1 0.1 7.5 0.3 0.2 10.1 2.6 0.1 0.4 0.0 0.0 0.4 0.1 1.9 1.4 7.3 0.9 1.0 0.0 0.0 1.1 0.9 0.0 0.0 0.0 0.8 0.8 1.4 1.0 0.0 1.6 3.6 0.0 0.0 0.0 2.8 1.2 0.8 6.2 1.7 0.0 0.5 1.8 0.0 0.0 0.0 0.0 0.5 0.0 2.1 2.9 0.4 0.0 5.0 1.1 0.4 0.7 1.5 3.6 2.0 1.1 1.2 0.0 0.3 5.1 1.0 1.7 2.9 0.4 0.1 2.4 0.4 1.5 1.6 1.4 4.1 0.8 0.7 2.3 0.9 0.7 0.9 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 1.4 0.8 0.4 3.2 3.3 12.6 18.6 7.2 7.5 2.6 1.9 0.2 9.6 10.5 0.0 0.0 0.0 0.3 0.0 0.0 0.7 1.3 0.6 0.0 0.0 27.9 0.0 0.0 0.1 0.1 0.2 1.9 0.3 56.8 153.5 1.9 0.8 0.0 0.0 0.0 0.0 0.1 1.0 0.0 4.8 2.5 0.1 0.4 0.2 0.2 0.0 0.0 0.6 0.0 0.6 0.0 85.0 0.3 0.5 0.0 0.0 0.0 0.8 1.0 0.0 0.0 0.0 0.1 0.7 0.1 0.4 0.5 0.4 189.5 0.4 0.0 0.4 0.3 14.3 0.9 0.0 0.0 0.0 0.3 1.4 0.3 0.2 CFAP251 "CaM-IP4, MGC33630, WDR66" ENSG00000158023 "Cilia and flagella associated protein 251" Q8TBY9 12 121918592-122003927 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 22.3;testis: 19.9" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 2.7;Fibroblasts: 1.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.6" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.6" "Cell line enhanced" "Detected in many" "HBEC3-KT: 31.8;hTCEpi: 30.8;hTERT-HME1: 19.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA039902, HPA040005" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 30: Epithelial cell lines - Translation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA039902: AB_10795236, HPA040005: AB_10795160" "unprognostic (4.92e-3)" "unprognostic (9.05e-2)" "unprognostic (7.99e-3)" "prognostic favorable (3.11e-4)" "unprognostic (5.58e-3)" "unprognostic (6.89e-3)" "unprognostic (1.44e-2)" "unprognostic (2.45e-1)" "unprognostic (2.89e-1)" "unprognostic (2.34e-1)" "unprognostic (7.72e-2)" "unprognostic (1.55e-1)" "unprognostic (2.43e-2)" "unprognostic (4.29e-2)" "unprognostic (1.37e-1)" "unprognostic (1.79e-2)" "unprognostic (1.35e-1)" 1.1 0.8 1.6 0.3 2.4 0.1 1.3 1.3 1.7 3.5 13.2 0.2 0.1 1.9 4.7 0.3 22.3 1.2 1.3 2.4 3.9 2.7 1.4 3.0 0.6 5.5 6.6 2.2 1.7 2.9 6.5 0.9 3.6 0.7 0.1 4.6 1.1 1.6 0.3 1.5 0.2 0.6 2.7 1.7 0.4 19.9 4.1 0.5 4.7 0.4 0.9 0.3 1.3 1.6 4.7 0.4 0.4 0.2 0.5 0.5 0.5 0.3 2.5 1.2 3.0 0.3 1.4 0.2 3.7 0.2 0.7 0.9 0.3 31.8 4.4 0.2 0.5 0.2 0.6 0.3 3.7 0.1 8.6 1.8 30.8 2.4 19.9 0.7 1.3 0.5 7.5 0.1 1.9 0.9 0.3 0.6 0.4 0.4 0.2 0.4 0.8 0.0 5.4 0.5 2.5 0.1 0.2 0.1 0.2 0.8 0.9 0.1 1.0 2.5 3.9 0.5 0.5 0.5 0.2 3.8 2.9 0.1 0.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.6 0.1 0.0 1.6 2.4 1.3 1.7 2.4 3.9 5.5 6.6 3.6 2.7 4.1 1.6 0.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 CFAP299 C4orf22 ENSG00000197826 "Cilia and flagella associated protein 299" Q6V702 4 80335730-80963750 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "fallopian tube: 19.8;testis: 27.4" "Cell type enriched" "Detected in some" 54 "Endometrial ciliated cells: 54.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 1.4;BJ: 1.6;hTERT-RPE1: 2.5;LHCN-M2: 1.0;SCLC-21H: 1.1;U-251 MG: 1.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA043383 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA043383: AB_10797140" "unprognostic (4.77e-4)" "unprognostic (1.52e-1)" "unprognostic (4.06e-2)" "unprognostic (1.45e-2)" "unprognostic (7.24e-2)" "unprognostic (3.27e-1)" "unprognostic (6.93e-2)" "unprognostic (5.90e-2)" "unprognostic (2.67e-3)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.79e-2)" "unprognostic (4.61e-2)" 0.1 0.0 0.9 0.0 1.0 0.0 0.1 1.4 0.5 0.7 2.6 0.1 0.1 0.2 0.0 0.0 19.8 0.1 0.0 1.0 1.0 0.3 0.0 1.4 0.1 5.3 3.7 0.1 0.0 0.0 0.1 0.0 2.3 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 27.4 1.2 0.1 0.6 0.0 0.0 0.0 0.0 1.1 1.4 0.0 0.0 0.0 0.1 0.7 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.5 0.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.9 1.0 1.4 0.5 1.0 1.0 5.3 3.7 2.3 3.5 1.2 1.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 54.5 0.3 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 CFAP65 "CCDC108, DKFZp434O0527, MGC35338" ENSG00000181378 "Cilia and flagella associated protein 65" Q6ZU64 2 219002846-219041527 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 12.1;choroid plexus: 13.5;fallopian tube: 25.7;testis: 9.4" "Group enriched" "Detected in many" 4 "Early spermatids: 204.5;Late spermatids: 164.3" "Cancer enhanced" "Detected in single" "endometrial cancer: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "midbrain: 10.8" "HPA055156, HPA063406" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA055156: AB_2682720, HPA063406: " "unprognostic (3.95e-2)" "unprognostic (1.80e-1)" "unprognostic (9.88e-3)" "prognostic favorable (6.08e-5)" "unprognostic (2.18e-2)" "unprognostic (1.04e-2)" "unprognostic (2.20e-1)" "unprognostic (3.76e-3)" "unprognostic (3.71e-1)" "unprognostic (3.03e-1)" "unprognostic (5.58e-3)" "unprognostic (1.43e-1)" "unprognostic (6.62e-3)" "unprognostic (8.04e-2)" "unprognostic (2.81e-2)" "unprognostic (9.60e-2)" "unprognostic (6.60e-2)" 0.0 0.1 2.3 0.0 2.1 0.0 0.1 1.0 1.0 1.3 13.5 0.1 0.0 0.5 1.8 0.0 25.7 0.4 0.0 2.6 2.8 0.4 0.0 2.7 0.0 8.4 12.1 0.0 0.3 0.1 3.5 0.0 6.2 0.1 0.2 9.2 0.1 0.1 0.0 0.0 0.4 0.0 6.1 0.0 0.3 9.4 2.4 0.0 0.9 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.9 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.1 1.0 1.0 2.6 2.8 8.4 12.1 6.2 6.1 2.4 3.2 0.1 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.8 7.7 8.8 0.0 4.3 6.8 0.0 12.5 0.0 0.1 1.1 0.0 0.6 204.5 45.1 0.5 0.2 29.1 0.0 0.0 1.5 0.0 0.2 2.0 1.8 0.0 0.2 0.0 0.1 0.1 0.0 0.0 25.2 0.0 0.0 0.0 164.3 0.6 0.2 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.1 1.8 0.7 0.0 1.1 1.9 1.1 29.2 19.5 0.0 0.1 0.0 14.4 5.7 0.0 0.0 0.0 0.2 0.1 5.1 0.1 CGN KIAA1319 ENSG00000143375 Cingulin Q9P2M7 1 151510510-151538692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 56.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 118.6;Distal enterocytes: 173.2;Paneth cells: 108.7;Proximal enterocytes: 88.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 91.4;CAPAN-2: 59.1;OE19: 58.6;RT4: 44.0" "Low region specificity" "Detected in many" "CAB017193, HPA027586, HPA027587, HPA027657" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017193: , HPA027586: AB_10600208, HPA027587: AB_10601884, HPA027657: AB_10611527" "unprognostic (1.57e-1)" "unprognostic (4.30e-2)" "unprognostic (1.12e-1)" "unprognostic (8.74e-3)" "unprognostic (1.02e-1)" "unprognostic (3.01e-1)" "unprognostic (1.98e-1)" "unprognostic (8.38e-2)" "unprognostic (4.61e-1)" "unprognostic (2.11e-2)" "unprognostic (2.96e-3)" "unprognostic (7.10e-2)" "prognostic favorable (5.84e-10)" "unprognostic (2.66e-1)" "unprognostic (3.00e-1)" "unprognostic (8.28e-2)" "unprognostic (2.10e-2)" 5.8 1.1 1.9 6.0 3.3 0.4 9.0 8.5 3.3 4.9 6.5 37.2 52.7 1.4 1.5 8.6 13.2 13.6 0.6 2.0 3.7 12.2 32.1 27.3 0.4 5.5 3.0 2.0 24.2 32.1 3.7 1.6 5.6 10.1 25.1 3.7 21.1 7.0 0.2 17.9 56.4 1.5 1.7 0.4 30.4 6.6 3.4 0.7 4.9 0.1 2.3 8.3 6.2 6.7 28.9 3.2 2.7 4.6 0.0 0.0 35.4 0.1 0.1 0.8 0.9 91.4 59.1 1.3 9.4 0.0 4.9 27.0 8.6 5.0 0.6 17.3 6.0 2.4 1.3 1.8 0.0 0.4 3.6 0.0 1.0 1.3 0.7 0.0 0.3 7.8 1.2 8.1 0.0 26.8 5.0 0.6 22.9 58.6 2.5 5.4 2.8 4.3 17.9 44.0 8.9 4.4 1.8 27.1 1.0 10.3 33.5 0.3 0.5 0.3 8.3 0.5 1.2 7.7 8.4 5.2 0.3 3.3 2.4 0.2 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.2 0.4 0.2 0.1 0.1 0.1 0.0 1.9 3.3 8.5 3.3 2.0 3.7 5.5 3.0 5.6 1.7 3.4 6.7 0.1 118.6 33.3 2.3 0.2 0.3 3.3 5.9 0.6 4.3 14.9 9.1 0.7 24.3 22.4 3.7 0.0 3.5 0.5 173.2 0.0 21.5 0.3 13.8 2.1 0.6 10.3 2.7 0.8 25.4 0.3 2.3 54.6 27.3 0.0 0.5 0.0 29.6 0.3 0.0 10.4 32.7 8.2 0.0 0.4 1.2 0.6 0.5 3.6 0.0 2.1 13.5 0.0 3.5 11.7 49.5 108.7 0.7 0.5 11.9 88.7 3.0 46.8 1.5 0.0 0.1 1.0 1.5 6.9 4.2 1.8 0.4 0.6 1.8 27.2 18.3 CHIC2 BTL ENSG00000109220 "Cysteine rich hydrophobic domain 2" Q9UKJ5 4 54009789-54064605 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 348.7;Suprabasal keratinocytes: 373.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Lineage enriched" "Detected in all" 4 "granulocytes: 365.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026782, HPA026784, HPA076603" Uncertain Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 38: Basophils - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 30: Epithelial cell lines - Translation" "Cluster 28: Keratinocytes - Keratinization" "Vesicles, Plasma membrane" "HPA026782: AB_1846654, HPA026784: AB_2732433, HPA076603: AB_2732317" "unprognostic (4.56e-2)" "unprognostic (2.24e-3)" "unprognostic (3.47e-3)" "unprognostic (9.58e-2)" "unprognostic (1.49e-1)" "unprognostic (2.25e-2)" "unprognostic (7.87e-2)" "unprognostic (1.22e-1)" "unprognostic (3.65e-2)" "unprognostic (7.81e-3)" "unprognostic (2.94e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (1.56e-4)" "unprognostic (2.89e-1)" "unprognostic (1.77e-1)" "unprognostic (4.56e-2)" "unprognostic (9.40e-2)" 20.8 15.9 9.1 12.9 8.5 27.1 18.1 12.6 9.6 16.0 12.1 12.4 12.3 12.3 10.3 27.4 12.1 20.5 15.1 8.6 9.2 14.2 20.3 19.7 14.7 8.6 8.5 13.0 9.9 6.5 9.3 13.5 9.0 12.9 8.9 5.9 15.2 5.7 9.8 27.5 13.2 10.5 7.8 17.3 12.9 39.6 9.2 21.9 11.9 6.6 13.3 15.1 18.1 9.7 25.4 4.6 12.8 11.9 21.5 16.8 13.1 34.6 36.1 20.1 20.3 18.1 22.0 21.4 29.5 22.0 17.2 7.7 17.9 25.1 22.0 11.9 9.5 11.7 4.2 13.6 65.1 19.2 23.4 22.6 19.8 30.3 45.3 38.3 30.0 22.2 13.0 15.4 40.6 7.1 22.3 30.7 8.7 11.2 16.9 14.3 7.3 8.4 23.3 8.1 19.7 18.3 8.3 12.2 26.6 18.3 6.1 26.8 51.3 25.2 19.9 36.6 21.4 18.4 9.5 17.2 18.7 18.7 18.7 365.5 79.3 171.5 60.1 64.7 57.7 41.3 60.0 68.6 55.9 40.1 54.6 59.6 325.0 74.2 68.3 47.0 81.5 77.9 9.1 8.5 12.6 9.6 8.6 9.2 8.6 8.5 9.0 7.8 9.2 9.7 58.1 6.4 7.3 35.6 42.5 348.7 95.5 61.0 68.3 8.1 61.6 33.5 4.1 15.7 25.9 7.3 8.4 27.8 57.8 27.2 17.6 42.8 55.4 64.1 58.0 64.3 25.8 72.6 39.7 28.0 38.7 80.8 32.6 34.2 36.3 36.8 38.6 23.9 24.7 13.5 40.2 21.9 40.7 36.4 144.2 13.4 17.1 50.3 67.6 49.6 32.6 9.0 28.8 74.4 23.2 61.8 42.1 24.5 40.2 85.1 41.9 29.2 56.0 7.2 19.7 53.9 45.1 163.5 89.9 97.4 373.8 47.7 65.8 39.8 21.0 135.9 CHRNA3 ENSG00000080644 "Cholinergic receptor nicotinic alpha 3 subunit" P32297 15 78593052-78621295 "Disease related genes, FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "adrenal gland: 39.3;lymphoid tissue: 65.8;retina: 53.5" "Cell type enriched" "Detected in some" 19 "Cone photoreceptor cells: 164.7" "Cancer enhanced" "Detected in some" "testis cancer: 1.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "SH-SY5Y: 356.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA029430 Enhanced Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Nuclear speckles" "HPA029430: AB_10603785" "unprognostic (2.28e-1)" "unprognostic (3.45e-1)" "unprognostic (2.58e-2)" "unprognostic (2.36e-1)" "unprognostic (1.32e-1)" "unprognostic (1.12e-1)" "unprognostic (9.16e-3)" "unprognostic (1.97e-1)" "unprognostic (4.28e-2)" "unprognostic (7.20e-2)" "unprognostic (3.12e-1)" "unprognostic (1.01e-1)" "unprognostic (1.86e-4)" "unprognostic (2.65e-3)" "unprognostic (2.76e-1)" "unprognostic (1.53e-1)" "unprognostic (4.48e-1)" 0.3 39.3 4.4 5.1 2.0 0.0 0.1 6.3 1.0 1.0 0.3 8.1 1.5 0.5 0.0 0.1 0.0 0.3 0.4 0.7 2.3 0.0 0.0 0.2 0.3 3.1 6.4 0.1 0.2 0.0 1.1 0.1 10.0 0.2 4.0 53.5 0.1 0.0 0.1 0.7 3.0 3.7 0.3 0.1 2.8 1.0 9.2 65.8 0.2 0.0 0.8 0.2 0.7 1.0 0.1 0.3 0.7 0.6 0.0 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.0 1.5 0.0 8.8 0.0 0.0 0.3 1.4 0.5 0.4 0.1 0.0 0.1 4.0 0.0 0.3 0.0 0.0 0.0 0.0 22.6 0.2 0.0 0.0 0.3 7.1 0.0 1.6 0.1 0.2 0.4 0.3 0.1 0.0 0.4 67.7 356.1 0.3 0.1 0.1 0.5 0.4 0.0 0.0 0.1 1.7 0.1 0.4 0.2 0.7 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 2.0 6.3 1.0 0.7 2.3 3.1 6.4 10.0 0.3 9.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.8 0.0 0.0 0.0 164.7 0.0 0.0 0.2 1.9 0.0 3.7 0.1 1.2 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.2 1.7 0.4 3.6 0.0 0.0 0.0 3.5 0.0 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.0 0.1 0.1 0.3 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.1 CHRNA5 ENSG00000169684 "Cholinergic receptor nicotinic alpha 5 subunit" P30532 15 78565520-78595269 "Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 13.0;Extravillous trophoblasts: 11.5;Intestinal goblet cells: 9.8;Spermatocytes: 12.4;Spermatogonia: 28.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA054381 Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Focal adhesion sites" "Plasma membrane" "HPA054381: AB_2682468" "unprognostic (2.66e-1)" "unprognostic (1.76e-1)" "unprognostic (2.32e-2)" "unprognostic (3.20e-3)" "unprognostic (6.66e-2)" "unprognostic (1.29e-3)" "unprognostic (7.03e-5)" "prognostic unfavorable (3.64e-5)" "unprognostic (1.34e-2)" "unprognostic (1.31e-2)" "unprognostic (4.52e-2)" "unprognostic (8.97e-2)" "unprognostic (6.50e-11)" "unprognostic (4.37e-1)" "unprognostic (5.39e-1)" "unprognostic (5.44e-2)" "unprognostic (2.22e-1)" 0.8 2.0 1.9 1.9 1.8 0.5 1.5 2.7 3.0 1.0 2.0 4.0 4.8 1.3 1.1 1.6 0.5 4.4 1.3 1.7 1.8 0.3 0.3 0.5 0.7 1.7 2.2 0.7 1.9 0.3 0.2 1.1 2.4 1.9 4.2 2.5 0.7 0.4 3.9 0.6 2.4 2.1 1.6 0.3 2.8 3.1 2.4 0.7 0.3 0.5 1.1 1.8 1.1 2.7 16.5 41.8 22.4 12.5 2.7 1.9 9.1 12.0 5.8 13.0 23.4 16.1 76.7 9.8 28.6 2.6 34.7 14.3 43.5 17.6 13.2 20.1 51.9 18.3 29.5 16.2 1.4 12.4 24.7 0.7 3.1 3.5 4.7 4.8 24.5 13.6 18.2 12.5 8.3 36.1 15.9 4.3 18.2 32.4 11.5 20.1 25.8 9.9 15.7 39.2 37.7 55.0 28.6 27.5 14.1 12.7 61.2 3.2 5.3 17.6 21.0 13.0 38.0 14.3 63.4 11.3 10.6 19.8 16.5 1.0 0.4 0.7 0.1 0.4 0.1 0.0 0.1 0.1 0.2 0.1 0.3 0.3 0.7 0.3 0.4 0.2 0.0 0.1 1.9 1.8 2.7 3.0 1.7 1.8 1.7 2.2 2.4 1.6 2.4 2.7 0.9 0.0 0.0 0.3 1.4 3.2 13.0 0.5 8.6 7.6 1.2 2.9 1.2 2.8 0.2 0.0 0.0 2.6 0.4 1.2 0.0 0.3 1.2 0.5 0.6 2.0 3.5 0.8 1.0 2.0 11.5 1.0 0.5 0.6 0.0 1.5 0.0 0.3 1.0 5.0 1.1 9.8 0.0 0.0 2.3 2.6 0.3 0.8 1.8 0.0 0.2 0.4 1.0 0.5 0.9 0.7 0.1 0.4 0.9 6.7 0.1 0.4 0.1 0.7 0.0 1.3 1.6 12.4 28.8 2.9 1.6 1.0 2.0 0.2 2.1 3.2 CIAO3 "FLJ21988, HPRN, IOP1, NAR1, NARFL, PRN" ENSG00000103245 "Cytosolic iron-sulfur assembly component 3" Q9H6Q4 16 729760-741329 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Cardiomyocytes: 11.6;Cytotrophoblasts: 20.6;Extravillous trophoblasts: 10.9;Hofbauer cells: 16.0;Syncytiotrophoblasts: 14.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "REH: 142.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040851 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA040851: AB_10794427" "unprognostic (6.31e-2)" "prognostic favorable (1.32e-5)" "unprognostic (7.61e-2)" "unprognostic (8.25e-2)" "unprognostic (1.01e-1)" "unprognostic (1.27e-3)" "unprognostic (8.85e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (8.39e-2)" "unprognostic (4.45e-3)" "unprognostic (3.02e-1)" "prognostic favorable (9.83e-5)" "unprognostic (2.49e-2)" "unprognostic (8.15e-2)" "unprognostic (2.62e-1)" "unprognostic (8.33e-3)" 10.4 13.8 16.8 7.5 18.0 10.7 12.3 17.2 27.2 11.6 14.1 16.1 13.3 12.1 11.5 18.5 12.2 6.7 23.1 17.6 16.0 19.5 22.4 9.4 11.7 17.6 17.1 10.1 15.7 12.1 14.9 5.8 17.8 18.9 4.9 4.5 16.8 9.2 20.5 18.1 16.5 4.8 16.3 17.3 16.1 11.3 16.6 12.0 13.0 13.2 7.9 13.1 13.7 17.5 9.1 26.1 10.1 14.9 10.3 7.3 24.6 12.7 9.4 17.2 15.0 18.8 22.0 12.9 19.2 8.0 12.7 20.3 10.0 15.4 6.1 24.1 22.8 10.9 14.7 15.5 13.2 19.3 15.0 9.2 19.1 10.2 8.5 11.4 12.9 50.7 20.3 12.0 8.5 33.9 17.5 9.0 8.6 18.4 16.5 142.5 15.3 23.7 10.6 9.0 11.8 16.1 15.3 36.0 13.4 6.0 33.0 19.7 14.0 14.5 13.6 16.1 11.5 15.8 12.1 35.7 9.9 11.0 19.0 2.7 11.1 8.9 10.9 9.9 8.3 14.8 11.0 8.9 11.9 9.2 8.6 12.4 2.3 15.5 11.6 9.4 11.7 9.9 16.8 18.0 17.2 27.2 17.6 16.0 17.6 17.1 17.8 16.3 16.6 17.5 3.4 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.6 0.0 0.0 0.0 0.0 20.6 3.2 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 10.9 2.1 0.0 0.0 0.0 0.0 0.0 0.0 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 14.2 0.5 0.0 0.0 0.0 CIB1 "CIB, KIP, SIP2-28" ENSG00000185043 "Calcium and integrin binding 1" Q99828 15 90229975-90234047 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Angiogenesis, Apoptosis, Cell adhesion, Cell cycle, Cell division, Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1385.8;Respiratory ciliated cells: 1103.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB012991, HPA042413, HPA048825" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoplasm, Plasma membrane" "CAB012991: AB_2533205, HPA042413: AB_2732498, HPA048825: AB_2680533" "unprognostic (1.20e-1)" "unprognostic (1.59e-1)" "unprognostic (1.73e-2)" "prognostic favorable (2.26e-5)" "unprognostic (7.56e-2)" "unprognostic (5.51e-2)" "unprognostic (1.21e-2)" "unprognostic (8.29e-3)" "unprognostic (1.77e-1)" "unprognostic (4.09e-2)" "unprognostic (5.25e-3)" "unprognostic (2.44e-1)" "unprognostic (1.29e-3)" "unprognostic (1.85e-1)" "unprognostic (6.31e-2)" "unprognostic (1.39e-1)" "unprognostic (2.68e-2)" 65.6 163.6 65.4 79.7 69.2 205.5 67.4 67.8 76.5 93.8 96.7 147.9 130.1 44.6 88.1 127.3 146.6 77.4 101.9 62.7 68.8 220.1 195.7 86.7 97.0 70.1 70.3 43.9 214.1 98.3 93.0 38.0 68.7 127.6 138.1 29.1 116.6 72.7 58.8 40.4 128.5 45.3 69.3 117.0 99.3 113.8 69.2 64.4 89.1 42.3 120.9 93.7 68.3 69.3 119.5 261.4 23.8 83.7 98.7 102.7 38.9 123.8 107.2 99.6 87.2 104.7 207.4 34.7 129.7 144.0 125.7 124.2 48.0 141.8 54.0 81.9 114.2 77.5 182.3 175.9 96.2 155.2 71.4 72.2 84.9 91.9 64.6 113.7 129.1 83.7 105.8 53.5 76.4 233.3 118.4 179.4 36.7 223.9 134.0 66.1 62.8 139.7 256.1 199.4 18.7 22.8 168.7 136.5 135.7 41.5 105.3 93.3 81.7 109.6 77.0 132.0 153.2 73.0 122.0 40.3 176.1 174.9 47.8 168.9 201.8 271.3 226.9 248.9 188.0 476.4 269.9 249.4 224.4 418.0 221.5 218.0 118.2 205.7 230.0 149.7 245.8 399.6 65.4 69.2 67.8 76.5 62.7 68.8 70.1 70.3 68.7 69.3 69.2 69.3 77.4 89.8 104.2 14.7 203.7 85.7 253.6 520.1 84.8 12.0 152.0 118.5 86.9 128.7 469.1 183.9 10.4 106.7 198.7 670.9 453.9 372.1 380.8 480.8 101.3 83.9 97.1 62.3 7.7 662.9 117.6 96.5 149.9 222.8 138.8 66.9 79.6 230.1 209.0 3.3 6.6 379.5 463.9 102.5 148.0 1385.8 105.3 180.5 128.1 4.7 187.5 138.4 184.4 5.0 12.2 620.2 794.2 92.6 88.8 699.6 661.4 668.6 1103.6 25.5 39.5 62.3 140.4 160.3 69.0 218.1 67.3 66.1 227.5 91.8 315.5 577.8 CIB3 KIP3 ENSG00000141977 "Calcium and integrin binding family member 3" Q96Q77 19 16161368-16173525 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "bone marrow: 1.2" "Group enriched" "Detected in some" 8 "Cardiomyocytes: 30.2;Late spermatids: 9.5" "Cancer enriched" "Detected in single" 7 "breast cancer: 0.9" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "eosinophil: 2.3" "Lineage enriched" "Detected in single" 10 "granulocytes: 2.3" "Cell line enhanced" "Detected in some" "HMC-1: 4.5;MCF7: 2.2;NB-4: 1.4;THP-1: 1.3;U-937: 2.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA043553, HPA043995" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "HPA043553: AB_10964566, HPA043995: " "unprognostic (8.43e-2)" "unprognostic (7.26e-5)" "unprognostic (3.18e-2)" "unprognostic (2.62e-1)" "unprognostic (5.32e-2)" "unprognostic (1.95e-2)" "unprognostic (1.25e-1)" "unprognostic (3.14e-1)" "unprognostic (2.93e-2)" "unprognostic (3.05e-1)" "unprognostic (5.68e-2)" "unprognostic (3.42e-1)" "unprognostic (1.54e-2)" 0.0 0.0 0.0 0.2 0.0 1.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 4.5 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.2 0.0 1.4 0.2 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.0 0.0 0.7 0.0 2.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.5 0.3 30.2 0.0 0.1 0.0 0.0 0.2 0.1 1.8 0.0 0.0 2.3 0.0 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 1.4 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 CIP2A KIAA1524 ENSG00000163507 "Cellular inhibitor of PP2A" Q8TCG1 3 108549864-108589644 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.5;lymphoid tissue: 6.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 9.6;Cytotrophoblasts: 8.0;Exocrine glandular cells: 7.3;Extravillous trophoblasts: 12.9;Granulosa cells: 25.3;Hofbauer cells: 8.1" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039570 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA039570: AB_10796329" "unprognostic (2.02e-1)" "unprognostic (1.54e-2)" "unprognostic (2.31e-3)" "prognostic unfavorable (6.24e-5)" "unprognostic (3.10e-2)" "unprognostic (1.07e-2)" "unprognostic (1.91e-7)" "unprognostic (2.80e-3)" "unprognostic (2.53e-3)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.18e-4)" "unprognostic (6.85e-2)" "prognostic unfavorable (1.42e-4)" "unprognostic (9.11e-3)" "unprognostic (3.73e-1)" "unprognostic (2.11e-1)" "unprognostic (1.25e-1)" 1.1 1.1 0.3 3.4 0.6 7.5 1.4 0.9 0.8 0.9 0.1 1.9 1.2 1.8 0.6 1.7 0.9 1.2 0.7 0.6 0.5 1.0 0.7 1.4 6.7 0.2 0.9 1.9 0.4 0.6 0.7 2.1 0.2 1.8 2.7 2.6 0.6 0.8 0.6 1.2 1.7 1.5 0.0 2.3 1.2 5.7 0.1 6.9 1.2 0.7 5.2 2.0 0.9 0.4 42.2 12.2 33.9 21.8 1.4 3.2 13.8 31.1 14.7 36.2 41.9 15.0 18.5 27.6 10.4 11.4 27.7 20.9 11.7 11.0 65.8 8.8 11.3 33.9 17.4 11.3 0.5 21.8 23.2 1.4 2.3 28.4 11.5 5.9 16.3 12.7 21.1 44.5 36.1 8.7 26.7 19.2 35.0 15.8 20.8 30.1 31.2 15.3 11.0 11.5 16.4 21.6 22.9 9.0 12.7 19.7 15.3 15.6 12.2 37.0 41.7 11.3 38.3 10.2 12.1 46.1 16.4 23.2 38.6 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.2 0.0 0.1 0.0 0.3 0.6 0.9 0.8 0.6 0.5 0.2 0.9 0.2 0.0 0.1 0.4 1.2 9.6 1.1 0.0 2.3 0.0 0.0 0.0 0.0 0.0 1.9 1.3 0.0 0.0 2.5 3.7 0.0 8.0 1.8 0.0 1.9 2.8 0.0 2.5 2.8 2.6 0.0 0.0 0.0 7.3 12.9 3.0 0.0 2.7 3.8 25.3 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 3.1 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.4 0.0 0.0 2.4 1.5 0.0 0.0 0.0 3.2 0.0 0.0 0.0 0.0 1.4 1.7 5.4 0.0 0.0 CLCN6 "CLC-6, KIAA0046" ENSG00000011021 "Chloride voltage-gated channel 6" P51797 1 11806096-11848079 "Plasma proteins, Predicted membrane proteins" "Antiport, Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032097 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 14: Monocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA032097: AB_10670827" "unprognostic (3.14e-2)" "unprognostic (1.14e-1)" "unprognostic (2.46e-1)" "unprognostic (8.83e-2)" "unprognostic (2.08e-1)" "unprognostic (3.84e-3)" "unprognostic (1.51e-3)" "unprognostic (6.49e-2)" "unprognostic (7.76e-2)" "unprognostic (6.61e-3)" "unprognostic (1.71e-3)" "unprognostic (3.44e-1)" "unprognostic (2.13e-2)" "unprognostic (6.91e-2)" "unprognostic (1.45e-1)" "unprognostic (1.69e-1)" "unprognostic (3.65e-2)" 13.6 14.8 19.1 7.5 19.1 7.7 11.9 17.3 21.3 14.8 8.2 13.7 6.3 12.6 8.7 7.4 12.6 4.9 13.2 18.0 23.5 11.8 13.7 13.8 7.4 29.6 29.5 18.6 9.2 6.0 20.2 6.4 32.1 12.5 4.8 15.2 7.8 5.5 11.6 9.8 13.0 7.3 15.4 12.0 10.5 17.1 22.5 5.3 14.4 8.1 6.1 11.5 11.1 19.4 5.1 6.4 13.9 11.1 15.2 15.4 3.8 4.1 11.1 7.1 11.7 8.6 15.9 7.9 4.4 5.5 19.3 8.8 9.0 8.8 6.7 3.6 4.5 9.4 13.8 12.1 20.1 3.9 7.6 10.1 6.2 12.7 7.7 9.4 6.9 9.6 10.6 11.7 7.8 3.1 5.7 13.4 5.7 3.3 4.5 7.0 7.4 8.6 9.7 4.4 5.7 9.6 3.9 5.1 13.0 9.5 5.0 10.6 7.4 6.5 7.0 10.1 3.3 7.2 4.0 17.6 8.5 10.2 5.3 0.0 0.8 0.0 0.4 0.6 0.3 0.6 0.2 0.3 0.6 0.9 0.2 0.3 0.0 0.1 1.6 0.6 0.0 0.4 19.1 19.1 17.3 21.3 18.0 23.5 29.6 29.5 32.1 15.4 22.5 19.4 6.4 19.2 23.6 6.8 12.5 3.4 3.7 5.1 6.2 21.7 5.6 4.7 23.5 8.6 7.0 3.7 14.6 3.7 2.5 5.8 0.0 4.5 15.0 7.7 6.6 6.5 6.6 8.2 9.0 4.6 2.9 8.5 12.2 9.8 2.5 12.6 7.1 7.9 7.5 26.9 9.4 2.9 4.1 10.8 7.8 9.0 7.5 10.2 1.8 9.4 7.4 7.7 3.1 9.0 8.8 5.6 4.4 7.2 3.9 4.7 6.3 3.9 8.9 17.0 0.0 8.9 6.4 9.3 9.8 4.8 3.1 4.1 3.8 8.0 3.2 4.5 CLEC4F "CLECSF13, FLJ39110, KCLR" ENSG00000152672 "C-type lectin domain family 4 member F" Q8N1N0 2 70808643-70820599 "Predicted membrane proteins" Endocytosis Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 17.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Horizontal cells: 5.0;Macrophages: 4.5;monocytes: 4.0;Rod photoreceptor cells: 6.8" "Low cancer specificity" "Detected in single" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "intermediate monocyte: 6.0;non-classical monocyte: 4.4" "Lineage enriched" "Detected in single" 12 "monocytes: 6.0" "Cell line enhanced" "Detected in single" "AN3-CA: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA056101 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 79: Retina - Phototransduction" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA056101: " "unprognostic (8.14e-3)" "unprognostic (3.73e-2)" "unprognostic (2.07e-2)" "unprognostic (2.46e-1)" "unprognostic (4.91e-2)" "unprognostic (5.41e-2)" "unprognostic (3.66e-2)" "unprognostic (2.07e-2)" "unprognostic (9.29e-2)" "unprognostic (3.45e-1)" "unprognostic (2.68e-4)" "unprognostic (2.62e-1)" "unprognostic (1.93e-1)" "unprognostic (1.91e-1)" "unprognostic (2.44e-2)" "unprognostic (9.59e-2)" "unprognostic (2.44e-1)" 1.5 0.0 0.1 0.6 0.0 0.0 1.1 0.1 0.2 2.7 0.1 0.7 1.6 1.6 0.8 0.7 1.4 1.0 0.7 0.1 0.1 0.6 0.7 0.9 1.2 0.0 0.0 0.6 0.3 0.0 0.6 0.1 0.1 1.5 0.8 17.2 1.7 0.9 1.0 1.3 4.5 1.2 0.0 3.4 0.6 1.0 0.1 0.2 0.3 0.6 0.8 0.7 1.1 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.3 0.1 0.0 0.1 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.7 0.0 0.5 0.0 0.3 0.3 0.0 0.0 0.6 0.4 0.2 0.3 0.3 0.0 0.0 0.0 10.4 0.0 0.2 0.0 0.0 0.0 1.9 0.0 0.0 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.0 0.1 0.0 0.0 1.0 2.3 1.4 0.0 4.5 0.0 0.0 4.0 0.8 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 CLEC5A "CLECSF5, MDL-1" ENSG00000258227 "C-type lectin domain containing 5A" Q9NY25 7 141927357-141947007 "Predicted intracellular proteins, Predicted membrane proteins" "Host-virus interaction, Immunity, Innate immunity" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "bone marrow: 41.3" "Group enriched" "Detected in some" 6 "Hofbauer cells: 18.0;Langerhans cells: 67.5;Macrophages: 58.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 8 "classical monocyte: 9.1" "Lineage enriched" "Detected in many" 8 "monocytes: 9.1" "Group enriched" "Detected in some" 23 "HL-60: 40.9;U-937: 157.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA054137 Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA054137: AB_2732582" "unprognostic (6.89e-2)" "unprognostic (1.07e-1)" "unprognostic (5.01e-2)" "unprognostic (1.28e-1)" "unprognostic (1.69e-2)" "unprognostic (4.56e-2)" "unprognostic (1.33e-5)" "unprognostic (4.57e-1)" "unprognostic (2.59e-1)" "prognostic unfavorable (2.21e-4)" "unprognostic (6.58e-3)" "unprognostic (1.06e-1)" "unprognostic (1.73e-2)" "unprognostic (3.00e-2)" "unprognostic (2.82e-1)" "unprognostic (7.23e-2)" "unprognostic (1.64e-1)" 1.1 1.8 1.1 7.3 1.2 41.3 0.6 1.3 2.6 0.7 2.1 0.2 0.1 0.3 0.0 1.2 0.5 1.8 0.5 1.0 3.3 0.5 1.8 4.0 0.1 2.2 3.3 0.3 1.3 1.2 0.5 0.9 2.2 0.4 0.3 1.0 1.2 0.5 0.0 2.6 0.0 1.3 1.6 1.1 0.2 0.5 4.9 0.6 0.7 0.0 0.1 2.3 0.6 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 40.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 157.3 0.0 0.0 9.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 1.1 0.0 0.0 0.2 0.0 1.8 1.1 1.2 1.3 2.6 1.0 3.3 2.2 3.3 2.2 1.6 4.9 2.4 0.1 0.0 4.8 0.7 0.6 1.9 0.0 0.0 0.0 0.2 0.1 0.1 0.3 1.5 5.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.1 3.5 0.0 0.0 0.1 0.0 0.2 0.8 0.0 0.0 2.5 0.0 0.0 0.0 18.0 0.0 0.2 0.0 0.0 4.7 67.5 0.7 0.0 58.1 1.8 7.5 6.4 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.9 0.4 0.0 0.0 0.2 0.0 0.1 0.0 1.4 0.3 0.4 0.0 0.0 0.0 CLECL1 DCAL1 ENSG00000184293 "C-type lectin like 1" Q8IZS7 12 9715860-9733299 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "intestine: 9.9;lymphoid tissue: 31.1" "Group enriched" "Detected in some" 4 "B-cells: 87.0;dendritic cells: 24.0;Hofbauer cells: 22.2;Kupffer cells: 82.3;Langerhans cells: 64.6;Macrophages: 23.9;monocytes: 55.9;Plasma cells: 42.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "memory B-cell: 120.9" "Lineage enriched" "Detected in many" 5 "B-cells: 120.9" "Group enriched" "Detected in some" 5 "HEL: 49.7;Karpas-707: 66.2;U-698: 173.0;U-937: 95.6" "Low region specificity" "Detected in many" HPA063928 Supported "Plasma membrane,Centriolar satellite" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Centriolar satellite" "HPA063928: " "unprognostic (2.18e-2)" "unprognostic (2.35e-3)" "unprognostic (2.20e-3)" "unprognostic (1.90e-3)" "unprognostic (3.66e-1)" "unprognostic (1.90e-3)" "unprognostic (2.83e-1)" "unprognostic (7.55e-4)" "unprognostic (5.10e-2)" "unprognostic (2.82e-1)" "unprognostic (1.09e-1)" "unprognostic (2.20e-1)" "unprognostic (3.91e-5)" "unprognostic (3.31e-1)" "unprognostic (2.45e-1)" "unprognostic (6.10e-2)" "unprognostic (7.39e-2)" 1.0 1.6 0.6 9.9 0.9 1.9 2.0 1.4 0.9 0.9 1.3 3.0 2.7 0.9 0.0 0.7 0.8 2.5 0.4 0.6 0.9 0.7 2.1 2.1 24.8 1.8 1.1 0.5 0.2 0.3 0.3 0.7 1.4 0.7 4.3 0.1 1.3 0.5 0.1 0.4 9.9 1.8 1.2 16.2 4.5 0.9 1.1 5.2 0.6 0.2 31.1 3.0 0.3 1.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 11.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 49.7 0.0 0.0 0.0 18.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 66.2 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.5 0.0 0.0 0.5 0.0 0.1 0.2 1.2 173.0 0.0 95.6 0.0 2.4 7.9 0.4 4.5 14.4 0.1 120.9 3.9 9.7 18.7 54.3 0.2 1.4 0.3 0.3 15.5 25.4 0.2 5.2 0.6 0.9 1.4 0.9 0.6 0.9 1.8 1.1 1.4 1.2 1.1 1.6 0.3 0.0 0.0 0.0 87.0 2.0 0.1 0.0 0.0 0.0 0.3 0.5 0.0 0.0 1.8 0.0 0.0 0.1 24.0 0.1 0.0 0.0 1.0 0.1 0.1 0.3 0.0 4.4 0.0 0.2 0.1 0.6 0.0 0.1 5.1 0.0 0.4 0.4 22.2 0.0 0.0 0.2 0.0 82.3 64.6 1.4 0.3 23.9 12.4 1.0 55.9 0.0 1.0 0.0 0.0 0.0 0.0 0.0 42.0 0.0 0.0 0.4 0.0 0.0 6.6 0.1 0.1 0.0 0.2 0.1 1.8 0.3 11.2 0.0 0.0 0.1 CLIC4 "CLIC4L, DKFZP566G223, H1, huH1, P64H1" ENSG00000169504 "Chloride intracellular channel 4" Q9Y696 1 24745382-24844321 "Predicted intracellular proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Proximal tubular cells: 346.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 13.4;naive B-cell: 11.9" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008019, HPA060804" Enhanced Supported "Plasma membrane,Centrosome" NA NA 5800000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Centrosome" "HPA008019: AB_1846946, HPA060804: AB_2684370" "unprognostic (7.35e-3)" "prognostic unfavorable (8.31e-4)" "unprognostic (5.54e-2)" "unprognostic (7.60e-2)" "unprognostic (2.92e-2)" "unprognostic (9.48e-2)" "unprognostic (6.78e-3)" "unprognostic (1.63e-2)" "unprognostic (5.50e-2)" "unprognostic (4.03e-3)" "unprognostic (1.98e-2)" "unprognostic (7.01e-2)" "prognostic favorable (1.48e-5)" "unprognostic (2.75e-3)" "unprognostic (2.17e-1)" "unprognostic (1.22e-2)" "unprognostic (3.82e-3)" 154.0 58.6 51.8 97.7 70.2 32.3 88.1 61.8 82.7 165.4 39.4 136.3 32.4 201.5 84.6 119.3 103.0 106.5 197.2 50.8 66.5 256.8 72.3 114.6 51.0 73.6 68.0 46.0 49.7 29.3 14.1 120.6 67.0 112.8 66.8 53.1 49.4 152.8 30.7 33.6 54.2 280.4 62.4 43.1 80.0 34.2 88.9 59.6 47.6 53.2 56.4 156.1 73.4 91.4 219.3 25.3 222.7 176.8 299.1 645.6 116.7 561.0 571.4 253.9 304.2 48.3 114.1 129.8 320.1 799.2 77.0 76.8 155.0 151.5 635.7 33.3 64.9 50.0 60.8 88.3 417.3 17.5 6.3 299.3 256.8 363.0 365.1 417.3 427.0 76.0 40.4 138.2 739.0 38.4 34.8 28.5 212.6 50.4 101.8 83.5 247.3 51.5 260.0 58.4 38.9 101.3 144.7 68.4 453.7 228.3 60.0 116.1 601.0 452.2 168.8 199.4 230.1 75.4 111.7 108.6 333.8 151.1 140.5 0.8 5.4 2.5 0.4 4.4 0.0 13.4 0.3 0.2 5.6 11.9 0.1 0.2 1.2 0.0 4.0 1.7 0.0 3.5 51.8 70.2 61.8 82.7 50.8 66.5 73.6 68.0 67.0 62.4 88.9 91.4 178.7 16.0 30.5 24.8 50.8 61.6 50.4 79.8 37.0 3.7 49.9 33.0 172.5 21.5 35.2 14.7 10.4 71.5 2.2 18.1 41.1 39.2 44.9 20.9 103.0 177.1 9.6 40.8 1.5 43.1 211.4 120.5 21.4 53.6 40.0 10.2 88.5 34.4 39.3 1.7 4.2 22.6 20.3 28.2 100.2 27.3 28.6 52.6 129.9 75.9 50.8 13.0 4.1 41.7 196.9 54.7 10.6 87.6 171.2 114.5 0.1 346.1 16.7 26.5 46.0 87.9 162.5 44.0 29.1 29.3 52.0 177.0 8.1 46.5 2.6 49.1 CLIC5 DFNB102 ENSG00000112782 "Chloride intracellular channel 5" Q9NZA1 6 45880827-46080348 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Transporters" "Hearing, Ion transport, Sensory transduction, Transport, Vision" "Chloride channel, Ion channel, Voltage-gated channel" "Deafness, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 102.7;skeletal muscle: 289.7;tongue: 98.3" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 509.6;Cardiomyocytes: 285.7;Distal enterocytes: 164.2;Late spermatids: 93.8;Proximal enterocytes: 126.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 11.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 5.1" "Lineage enriched" "Detected in single" 17 "T-cells: 5.1" "Cell line enhanced" "Detected in some" "CAPAN-2: 13.5;EFO-21: 9.2;HDLM-2: 4.7;REH: 11.9;U-266/70: 12.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074371 Supported "Nuclear speckles,Plasma membrane" NA NA 400000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Nuclear speckles" "HPA074371: " "unprognostic (4.95e-2)" "unprognostic (1.59e-2)" "unprognostic (8.84e-2)" "unprognostic (5.05e-2)" "unprognostic (2.44e-1)" "unprognostic (6.73e-2)" "unprognostic (3.37e-1)" "unprognostic (1.26e-1)" "unprognostic (1.79e-1)" "unprognostic (6.46e-2)" "unprognostic (5.50e-2)" "unprognostic (3.65e-1)" "unprognostic (6.77e-3)" "unprognostic (1.22e-1)" "unprognostic (1.99e-1)" "unprognostic (8.26e-2)" "unprognostic (1.01e-1)" 18.9 1.5 3.2 4.3 4.4 0.2 6.5 1.5 2.9 19.0 0.5 28.6 20.9 2.1 0.9 2.9 4.5 3.0 102.7 2.1 5.0 54.7 0.3 70.8 1.7 2.1 3.8 0.5 1.1 1.7 3.0 16.5 2.2 2.6 25.8 16.9 2.7 1.4 289.7 1.2 36.6 2.3 1.8 44.5 1.6 1.4 5.5 1.0 7.3 98.3 1.9 2.0 2.6 1.9 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 13.5 0.0 9.2 0.0 0.0 0.3 0.0 0.1 0.0 4.7 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.8 0.0 0.0 0.0 0.1 0.4 1.6 0.0 11.9 0.3 0.1 0.1 0.4 0.1 0.0 0.0 0.0 0.0 2.9 0.0 0.0 0.0 0.0 0.4 0.1 0.0 12.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 1.5 0.0 5.1 0.1 2.0 1.3 0.0 0.0 0.3 0.2 0.0 0.3 0.0 0.0 1.0 0.5 3.2 4.4 1.5 2.9 2.1 5.0 2.1 3.8 2.2 1.8 5.5 1.9 59.6 509.6 30.0 4.6 1.4 0.1 0.1 0.0 1.2 0.3 0.5 0.4 285.7 5.7 26.9 14.7 0.0 0.2 0.7 164.2 0.0 1.7 52.9 4.6 0.5 29.8 13.1 0.4 8.6 0.2 0.1 7.9 0.5 5.7 1.3 0.0 0.7 0.0 0.0 0.0 5.4 23.5 0.0 0.0 0.0 93.8 0.9 0.7 0.0 34.7 0.6 53.8 0.0 0.5 2.9 2.9 51.1 0.7 3.4 3.2 126.0 2.9 11.4 1.8 0.0 6.1 4.3 1.0 0.1 0.1 0.1 2.2 5.8 0.1 13.5 4.3 CLUL1 ENSG00000079101 "Clusterin like 1" Q15846 18 596988-650334 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 31 "retina: 297.9" "Cell type enriched" "Detected in many" 7 "Rod photoreceptor cells: 407.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 34.3" "Not detected" "Not detected" "CAB025264, HPA075240" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted in other tissues" NA NA 11000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 79: Retina - Phototransduction" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 46: Photoreceptor cells - Phototransduction" "Endoplasmic reticulum" "Plasma membrane" "CAB025264: , HPA075240: AB_2732286" "unprognostic (1.75e-2)" "unprognostic (9.15e-2)" "unprognostic (1.50e-1)" "unprognostic (1.51e-1)" "unprognostic (7.81e-3)" "unprognostic (3.00e-3)" "unprognostic (1.96e-1)" "unprognostic (2.97e-3)" "unprognostic (8.38e-3)" "unprognostic (3.76e-2)" "unprognostic (4.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.36e-4)" "unprognostic (1.32e-1)" "unprognostic (7.89e-2)" "unprognostic (1.29e-3)" "unprognostic (2.37e-2)" 0.4 1.0 2.7 0.5 6.1 3.9 2.3 2.0 4.0 1.5 7.2 0.9 0.5 1.4 0.5 1.2 1.8 2.0 0.3 3.1 4.2 5.3 0.5 1.4 0.7 3.0 3.4 4.9 1.3 3.6 3.9 0.6 3.1 8.5 0.1 297.9 2.3 1.1 0.2 0.7 1.4 0.1 3.1 0.1 3.1 2.6 4.3 1.7 6.8 0.0 0.0 0.8 0.1 9.5 3.6 5.4 10.1 6.8 0.0 0.0 6.1 3.9 0.3 0.0 0.0 4.2 2.1 4.3 1.0 0.0 3.6 1.5 0.0 0.6 0.0 3.6 9.3 7.3 2.9 34.3 0.0 2.5 1.3 0.3 0.0 0.0 0.0 1.7 0.4 10.5 10.5 12.3 0.0 1.2 4.4 7.8 0.7 4.4 2.4 8.8 4.8 15.5 1.1 1.1 8.8 6.2 4.0 2.5 3.4 8.0 3.3 1.0 0.8 4.0 5.7 2.8 2.0 6.9 13.3 9.7 3.2 4.7 3.5 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.1 0.3 0.0 0.0 0.2 0.3 0.0 2.7 6.1 2.0 4.0 3.1 4.2 3.0 3.4 3.1 3.1 4.3 9.5 0.1 0.0 2.6 0.3 0.1 0.0 3.8 1.5 2.8 29.6 2.8 5.0 0.2 0.0 1.7 0.0 20.9 0.8 0.0 0.1 1.9 0.4 0.7 2.5 0.3 2.0 0.0 0.0 5.2 0.2 0.1 0.4 0.0 3.2 0.0 3.5 0.0 0.0 0.2 16.8 3.8 0.0 0.0 0.0 0.3 0.8 0.9 0.2 0.0 1.0 0.0 58.1 0.0 0.0 4.9 0.0 0.0 1.2 0.0 5.5 0.0 0.5 2.4 407.5 6.6 0.0 0.3 10.6 8.6 0.2 0.1 0.4 0.1 17.3 0.1 1.6 CNGA4 "CNCA2, CNG5, CNGB2, OCNC2, OCNCb" ENSG00000132259 "Cyclic nucleotide gated channel subunit alpha 4" Q8IV77 11 6234765-6244479 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Olfaction, Sensory transduction, Transport" "Ion channel, Ligand-gated ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "fallopian tube: 17.3;testis: 6.1" "Cell type enhanced" "Detected in some" "Astrocytes: 9.1;Early spermatids: 5.0;Endometrial ciliated cells: 2.7;Excitatory neurons: 3.0;Inhibitory neurons: 2.5;Late spermatids: 3.6;Oligodendrocytes: 3.1;Respiratory ciliated cells: 3.5" "Cancer enriched" "Detected in single" 6 "endometrial cancer: 2.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA074128 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 64: Astrocytes - Nervous system maintenance" "Nucleoplasm, Plasma membrane" "HPA074128: " "unprognostic (1.11e-2)" "unprognostic (4.32e-2)" "unprognostic (2.69e-3)" "prognostic favorable (1.48e-4)" "unprognostic (4.96e-2)" "unprognostic (1.09e-1)" "unprognostic (2.01e-3)" "unprognostic (1.89e-1)" "unprognostic (8.51e-2)" "unprognostic (5.51e-2)" "unprognostic (1.83e-2)" "unprognostic (8.70e-2)" "unprognostic (1.03e-3)" "unprognostic (3.84e-2)" "unprognostic (3.47e-2)" "unprognostic (8.11e-2)" "unprognostic (3.55e-3)" 0.1 0.2 1.2 0.2 1.3 0.4 0.2 1.3 1.2 0.7 0.7 0.2 0.3 0.6 0.2 0.2 17.3 0.2 0.1 1.4 1.4 0.4 0.2 1.4 0.2 2.8 3.8 0.4 0.4 0.0 0.7 0.0 2.5 0.2 0.1 1.1 0.1 0.5 0.0 0.3 0.2 0.1 1.8 0.3 0.2 6.1 1.2 0.3 0.2 0.0 0.2 0.2 0.2 1.9 0.0 0.1 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.2 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.8 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.3 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 1.3 1.3 1.2 1.4 1.4 2.8 3.8 2.5 1.8 1.2 1.9 0.0 0.0 0.0 9.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 2.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 1.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.5 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 CNKSR2 "CNK2, KIAA0902, KSR2" ENSG00000149970 "Connector enhancer of kinase suppressor of Ras 2" Q8WXI2 X 21372801-21654695 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 22.6;retina: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 111.7;Excitatory neurons: 497.7;Inhibitory neurons: 143.6;Oligodendrocyte precursor cells: 93.5;Rod photoreceptor cells: 86.1" "Cancer enhanced" "Detected in some" "glioma: 2.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 5.9;AF22: 4.0;NTERA-2: 8.9;PC-3: 4.8;RH-30: 8.2;U-251 MG: 5.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001502 Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 58: Brain - Synaptic function" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Golgi apparatus, Plasma membrane" "HPA001502: AB_1078542" "unprognostic (1.33e-2)" "unprognostic (1.00e-3)" "unprognostic (5.35e-2)" "unprognostic (4.90e-4)" "unprognostic (1.26e-1)" "unprognostic (5.40e-2)" "unprognostic (4.35e-3)" "unprognostic (2.58e-2)" "unprognostic (3.47e-1)" "unprognostic (7.16e-2)" "unprognostic (1.35e-2)" "unprognostic (2.01e-1)" "unprognostic (1.78e-2)" "unprognostic (2.72e-2)" "unprognostic (3.93e-2)" "unprognostic (2.27e-2)" "unprognostic (4.13e-2)" 1.5 2.6 8.4 0.3 12.2 0.2 1.4 22.6 16.4 1.0 0.0 0.7 0.1 0.3 0.5 0.0 1.3 0.1 0.8 20.3 0.0 0.1 0.7 1.2 0.9 0.0 0.0 0.6 2.5 0.0 1.6 0.1 0.0 0.7 0.0 17.9 0.5 0.1 4.7 0.8 0.6 0.1 0.0 0.5 1.2 0.6 0.0 0.9 0.9 1.3 1.0 0.6 0.9 5.3 0.0 5.9 4.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.6 0.0 0.0 1.2 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 2.0 0.0 8.9 0.0 4.8 0.0 8.2 0.0 0.0 0.0 3.9 1.6 0.0 0.1 0.3 2.1 0.0 0.6 0.0 0.1 1.9 0.0 5.3 3.1 0.0 3.4 0.8 0.0 2.3 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.1 0.0 0.0 0.9 0.8 0.2 0.0 0.0 0.0 0.0 0.2 0.1 8.4 12.2 22.6 16.4 20.3 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.3 16.0 1.3 111.7 9.0 1.3 0.5 0.0 1.2 17.8 0.3 0.6 5.7 1.5 5.6 0.0 20.9 0.1 2.1 0.4 0.0 0.3 0.3 1.0 13.6 0.3 0.0 0.8 497.7 2.3 0.0 6.7 0.0 1.3 1.3 1.0 0.0 2.1 0.1 23.5 143.6 0.5 0.0 0.0 2.6 0.0 0.6 0.2 0.0 15.9 0.2 12.7 0.0 93.5 10.6 0.6 0.1 1.5 3.1 2.0 1.3 0.3 0.0 86.1 0.0 0.6 0.9 6.0 7.7 0.1 1.8 0.0 2.9 1.5 0.4 0.0 CNNM1 ACDP1 ENSG00000119946 "Cyclin and CBS domain divalent metal cation transport mediator 1" Q9NRU3 10 99329356-99394330 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 16.7;testis: 9.8" "Cell type enhanced" "Detected in many" "Early spermatids: 103.1;Excitatory neurons: 69.9;Horizontal cells: 50.5;Inhibitory neurons: 89.5;Late spermatids: 88.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 19.6;BJ hTERT+: 7.4;BJ hTERT+ SV40 Large T+ RasG12V: 11.3;HAP1: 8.7;OE19: 7.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040408 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA040408: AB_10793963" "unprognostic (9.04e-4)" "unprognostic (2.93e-1)" "unprognostic (1.70e-1)" "unprognostic (7.60e-4)" "unprognostic (4.08e-3)" "unprognostic (9.51e-2)" "unprognostic (6.01e-2)" "unprognostic (2.27e-2)" "unprognostic (6.03e-2)" "unprognostic (1.94e-1)" "unprognostic (3.09e-2)" "unprognostic (2.45e-1)" "unprognostic (8.94e-2)" "unprognostic (1.50e-1)" "unprognostic (4.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.03e-1)" 0.2 1.1 9.9 0.2 9.9 0.0 0.5 5.4 16.7 1.8 0.0 0.7 0.4 0.9 1.7 0.8 1.0 0.3 0.1 7.3 7.3 1.7 0.2 0.1 0.0 3.6 2.9 2.6 1.1 0.6 3.6 0.0 3.5 1.7 0.4 5.2 0.8 0.8 0.0 1.2 0.6 0.4 2.0 0.1 0.6 9.8 4.7 0.1 0.1 0.1 0.1 1.7 1.4 10.1 0.0 19.6 0.0 0.0 0.0 0.0 0.0 2.8 7.4 6.7 11.3 0.0 4.4 0.0 0.0 1.4 0.1 1.7 8.7 0.0 4.8 0.0 0.9 1.9 2.8 3.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 4.3 0.0 0.1 0.0 0.0 0.4 2.7 0.3 0.0 0.9 7.7 0.8 0.0 0.0 0.0 0.9 0.0 2.2 6.1 2.0 0.4 1.0 0.5 0.0 0.0 0.0 0.6 0.1 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.9 9.9 5.4 16.7 7.3 7.3 3.6 2.9 3.5 2.0 4.7 10.1 0.6 0.0 0.0 4.6 0.0 2.3 3.3 0.1 5.2 25.3 0.7 2.8 1.4 0.0 0.2 1.8 14.6 0.0 0.0 0.0 0.0 0.6 103.1 0.5 1.0 0.4 0.0 0.8 69.9 1.5 0.0 1.0 0.0 0.3 0.0 0.2 1.8 0.0 0.0 50.5 89.5 0.1 0.0 0.0 0.8 88.0 2.1 0.3 1.8 4.7 0.1 1.3 0.0 10.6 2.2 2.0 0.3 2.6 0.0 5.9 0.1 0.7 0.6 3.4 0.0 2.0 0.5 1.9 1.6 1.5 1.0 0.0 0.2 1.2 0.1 2.4 CNNM4 "ACDP4, KIAA1592" ENSG00000158158 "Cyclin and CBS domain divalent metal cation transport mediator 4" Q6P4Q7 2 96760902-96811874 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Biomineralization, Ion transport, Sensory transduction, Transport, Vision" "Amelogenesis imperfecta, Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 38.8" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 112.6;Distal enterocytes: 103.4;Rod photoreceptor cells: 51.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in all" "SK-BR-3: 45.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017732 Enhanced Uncertain "Plasma membrane,Actin filaments" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Actin filaments" "Plasma membrane" "HPA017732: AB_1847395" "unprognostic (1.98e-3)" "unprognostic (8.95e-3)" "unprognostic (1.11e-1)" "prognostic unfavorable (9.14e-4)" "unprognostic (3.42e-2)" "unprognostic (5.28e-2)" "unprognostic (1.54e-3)" "unprognostic (3.36e-2)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.75e-4)" "unprognostic (4.75e-3)" "unprognostic (3.72e-1)" "unprognostic (8.14e-2)" "unprognostic (3.13e-1)" "unprognostic (3.44e-2)" "unprognostic (1.15e-2)" "unprognostic (1.06e-1)" 2.8 3.6 5.0 6.1 6.8 4.9 7.0 11.2 5.4 5.8 2.8 32.4 6.2 4.0 4.7 7.1 10.4 4.4 12.5 4.9 4.4 6.8 4.4 8.0 4.6 4.1 4.5 5.1 7.4 6.3 9.1 5.8 4.2 5.7 34.3 38.8 6.8 5.1 24.8 7.2 11.3 4.7 3.5 5.3 12.8 7.9 4.5 3.5 9.5 13.1 4.9 5.5 6.4 5.7 11.1 7.2 5.7 10.5 5.8 3.9 15.6 4.8 6.8 6.9 9.3 13.2 11.8 8.1 13.5 5.0 9.5 14.1 14.9 8.1 6.3 16.3 11.7 6.4 4.8 7.2 8.1 3.1 6.2 3.8 10.0 11.0 6.6 4.6 3.8 8.0 3.3 22.3 3.6 15.7 6.6 4.5 7.5 20.5 9.8 9.7 2.6 9.3 6.9 8.6 26.7 8.0 9.1 45.7 6.8 15.9 22.3 5.3 3.4 4.0 8.9 8.8 5.4 7.7 6.6 4.0 5.9 6.1 7.2 1.2 0.4 0.1 0.8 0.4 0.2 0.9 0.4 0.4 0.6 0.5 0.2 0.5 0.2 0.2 0.7 0.4 0.2 0.3 5.0 6.8 11.2 5.4 4.9 4.4 4.1 4.5 4.2 3.5 4.5 5.7 4.5 38.5 7.7 12.4 6.4 5.7 4.9 4.0 4.6 43.1 14.7 11.2 14.1 4.3 11.6 7.3 112.6 5.4 6.1 103.4 0.0 3.2 4.9 14.3 4.4 4.0 10.1 0.8 9.8 4.2 1.7 3.2 12.2 16.1 1.3 5.9 2.2 3.3 3.3 33.7 8.3 26.4 6.1 5.4 4.8 1.6 0.9 5.9 0.0 8.4 2.3 8.3 2.1 11.1 14.6 5.2 21.3 1.2 4.5 4.1 22.3 1.2 10.6 51.5 0.0 4.6 4.3 4.6 2.5 7.3 4.1 6.7 5.4 6.7 26.5 6.1 CNR1 "CANN6, CB-R, CB1, CB1A, CB1K5, CNR" ENSG00000118432 "Cannabinoid receptor 1" P21554 6 88139864-88166359 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets, Obesity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 23.0;brain: 25.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 44.6;Inhibitory neurons: 200.3;Sertoli cells: 98.6" "Cancer enriched" "Detected in many" 13 "glioma: 12.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "ASC diff: 81.4;HSkMC: 53.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042256, HPA069945" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 10: Brain - Neuronal signaling" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Actin filaments" "HPA042256: AB_2677917, HPA069945: " "unprognostic (1.28e-1)" "unprognostic (7.04e-2)" "unprognostic (4.61e-2)" "unprognostic (4.08e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-3)" "unprognostic (1.37e-1)" "unprognostic (2.07e-2)" "unprognostic (2.49e-1)" "unprognostic (1.16e-2)" "unprognostic (2.74e-2)" "unprognostic (2.68e-1)" "unprognostic (1.70e-1)" "unprognostic (5.59e-3)" "unprognostic (2.68e-3)" "unprognostic (5.88e-2)" "unprognostic (7.00e-2)" 23.0 5.4 10.4 3.5 25.1 0.7 16.9 7.5 22.8 5.7 0.0 12.3 1.1 6.9 2.6 2.4 11.2 2.0 1.0 19.5 11.8 0.9 0.1 4.0 4.4 9.9 1.1 3.8 1.5 0.5 20.7 3.1 0.5 2.9 2.9 1.5 2.6 2.1 2.4 3.8 10.5 3.6 0.0 1.7 4.3 1.2 18.0 1.3 5.1 1.2 6.6 4.1 5.1 3.0 0.0 0.1 3.8 0.0 81.4 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.2 1.9 2.9 0.0 5.3 0.0 0.0 53.8 0.0 0.0 0.1 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.4 0.5 0.0 6.8 0.0 1.7 0.1 0.0 0.0 0.0 0.3 0.0 1.4 4.9 0.0 0.0 0.1 0.0 0.0 1.6 7.1 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 10.4 25.1 7.5 22.8 19.5 11.8 9.9 1.1 0.5 0.0 18.0 3.0 3.4 0.0 10.4 3.6 7.1 0.6 0.5 0.0 0.0 1.7 0.1 0.4 0.9 1.5 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.2 0.0 0.4 3.8 0.0 0.0 44.6 0.0 0.0 0.9 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 200.3 0.0 0.0 0.3 0.8 0.0 1.5 0.2 0.0 5.6 0.0 0.0 0.0 9.0 3.2 0.0 0.1 0.4 4.2 0.0 0.0 0.0 0.0 0.2 98.6 6.4 12.4 0.0 0.5 0.2 0.1 0.1 0.5 0.0 0.0 0.8 COBL KIAA0633 ENSG00000106078 "Cordon-bleu WH2 repeat protein" O75128 7 51016212-51316818 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 118.2;skeletal muscle: 131.6;tongue: 107.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 198.7;Oligodendrocyte precursor cells: 353.9;Oligodendrocytes: 548.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 14 "plasmacytoid DC: 1.4" "Lineage enriched" "Detected in single" 14 "dendritic cells: 1.4" "Cell line enhanced" "Detected in many" "BEWO: 33.7;HeLa: 57.0;OE19: 53.4;RPMI-8226: 45.5;SuSa: 32.6;U-266/84: 34.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019033, HPA019167" Enhanced Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cell Junctions" "HPA019033: AB_2083648, HPA019167: AB_1847070" "unprognostic (8.09e-2)" "unprognostic (1.08e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-3)" "unprognostic (3.13e-1)" "unprognostic (5.33e-3)" "unprognostic (2.90e-1)" "unprognostic (5.29e-2)" "unprognostic (1.70e-1)" "unprognostic (1.17e-1)" "unprognostic (3.51e-2)" "unprognostic (3.92e-2)" "prognostic favorable (5.21e-12)" "unprognostic (7.64e-2)" "unprognostic (1.79e-1)" "unprognostic (2.08e-1)" "unprognostic (5.41e-3)" 3.0 1.0 83.8 1.4 96.7 0.0 14.8 62.0 91.1 4.8 41.6 13.3 18.9 2.2 2.1 13.6 19.1 5.8 54.8 81.8 67.9 12.9 19.6 13.8 0.2 76.6 88.3 2.8 18.4 31.5 12.8 4.7 69.2 14.4 10.9 23.3 47.3 4.2 131.6 27.5 21.5 2.7 66.6 0.3 17.6 3.0 89.8 1.3 8.3 107.9 1.0 1.8 5.8 118.2 12.4 8.8 0.2 0.3 0.0 0.0 33.7 0.0 0.0 0.0 0.0 24.1 18.2 0.0 0.9 0.0 1.4 21.1 12.0 0.0 0.0 0.0 9.6 0.0 57.0 4.7 0.0 0.0 0.1 1.5 2.3 0.0 0.0 0.0 0.0 1.6 6.5 0.2 0.2 7.9 0.1 0.1 9.0 53.4 8.0 0.1 0.5 45.5 17.4 0.0 11.0 0.2 3.2 26.2 3.9 32.6 16.6 0.1 0.0 0.0 9.8 0.3 0.9 0.0 34.1 0.1 0.1 0.1 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.0 83.8 96.7 62.0 91.1 81.8 67.9 76.6 88.3 69.2 66.6 89.8 118.2 1.4 38.5 19.6 48.0 1.0 17.8 3.4 1.2 4.0 2.3 38.0 34.7 76.2 28.6 13.2 9.2 58.4 23.3 4.6 59.4 0.0 21.5 3.8 65.9 3.3 2.2 18.6 0.0 198.7 9.7 9.2 7.7 35.7 74.6 10.1 4.6 0.4 29.7 2.2 0.0 96.6 35.2 4.1 0.8 1.7 3.1 0.6 0.9 16.0 10.3 1.1 94.4 0.0 353.9 548.8 23.2 35.0 0.4 0.2 25.3 76.8 18.6 31.4 73.6 0.0 10.5 1.5 0.7 8.8 6.8 35.7 40.2 1.7 11.2 14.4 7.3 COL16A1 ENSG00000084636 "Collagen type XVI alpha 1 chain" Q07092 1 31652263-31704319 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 109.0;Oligodendrocyte precursor cells: 62.4;Oligodendrocytes: 122.0;Peritubular cells: 91.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 133.1;ASC TERT1: 102.9;BJ hTERT+: 115.9;fHDF/TERT166: 106.5;HSkMC: 98.7;U-2197: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA027237 Uncertain "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 960000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA027237: AB_10600699" "unprognostic (2.25e-2)" "unprognostic (9.88e-2)" "unprognostic (5.64e-2)" "unprognostic (8.43e-2)" "prognostic unfavorable (8.08e-4)" "unprognostic (1.00e-1)" "unprognostic (3.99e-2)" "unprognostic (2.04e-1)" "unprognostic (4.48e-3)" "unprognostic (1.66e-3)" "unprognostic (1.44e-1)" "unprognostic (2.43e-1)" "prognostic unfavorable (4.00e-9)" "unprognostic (9.62e-2)" "unprognostic (6.13e-2)" "unprognostic (4.60e-2)" "unprognostic (2.15e-2)" 33.6 17.3 19.0 14.4 44.7 0.3 41.0 35.9 32.4 169.7 7.6 78.9 14.8 93.6 23.7 22.4 37.4 39.4 33.6 18.9 29.8 11.5 3.2 31.1 8.5 55.5 43.2 177.9 7.8 3.5 28.6 21.1 48.6 102.8 10.9 8.8 35.5 91.3 8.4 69.3 35.8 56.2 34.0 9.9 42.1 40.9 40.3 5.6 46.8 7.4 4.1 106.9 86.8 57.5 0.1 2.0 0.0 0.1 133.1 102.9 14.6 60.5 115.9 15.1 16.1 0.4 11.0 0.0 1.9 106.5 2.3 48.3 0.0 65.8 3.5 0.0 0.2 0.0 8.1 21.3 45.1 0.0 0.3 98.7 44.6 43.2 22.7 3.8 0.1 0.3 0.0 0.2 2.1 0.0 0.1 0.5 0.1 0.4 0.2 0.2 1.3 0.4 0.0 0.4 1.5 2.7 7.3 1.2 9.6 0.5 1.2 0.0 0.2 52.3 52.5 92.1 1.3 0.1 0.2 0.0 36.1 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 19.0 44.7 35.9 32.4 18.9 29.8 55.5 43.2 48.6 34.0 40.3 57.5 4.3 9.6 3.9 109.0 0.1 30.7 14.8 37.5 15.9 2.4 7.9 21.3 8.4 0.0 9.8 18.4 2.1 1.9 0.6 2.0 0.0 4.6 13.6 2.6 11.5 2.8 27.6 0.4 23.9 0.7 3.8 54.3 8.2 2.4 7.0 0.2 5.0 0.0 1.3 0.0 8.2 30.9 8.2 0.6 11.4 26.8 43.8 0.7 14.2 10.3 0.0 31.3 0.0 62.4 122.0 1.2 4.7 91.4 0.3 9.3 16.8 2.1 15.0 2.5 0.0 5.4 25.0 14.9 3.8 1.9 21.2 2.2 2.2 0.5 6.8 15.3 COL17A1 "BP180, BPAG2" ENSG00000065618 "Collagen type XVII alpha 1 chain" Q9UMD9 10 104031286-104085880 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "skin 1: 580.3" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 585.7;Basal respiratory cells: 136.0;Basal squamous epithelial cells: 299.9;Distal enterocytes: 211.5;Proximal enterocytes: 108.5;Suprabasal keratinocytes: 139.4" "Cancer enriched" "Detected in many" 5 "head and neck cancer: 227.4" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 204.3;HaCaT: 463.8;HBEC3-KT: 745.8;hTCEpi: 914.1;hTERT-HME1: 783.7" "Region enriched" "Detected in single" 4 "cerebellum: 1.0" "Low region specificity" "Detected in many" "HPA043673, HPA052963" Enhanced Supported "Golgi apparatus,Plasma membrane" "Secreted to extracellular matrix" NA NA 32000 "Cluster 1: Neutrophils - Mixed function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA043673: AB_10960893, HPA052963: AB_2681999" "prognostic favorable (1.38e-4)" "unprognostic (1.33e-1)" "unprognostic (4.01e-1)" "unprognostic (1.01e-1)" "unprognostic (9.65e-2)" "unprognostic (3.75e-1)" "unprognostic (2.13e-1)" "unprognostic (6.82e-3)" "unprognostic (1.63e-1)" "unprognostic (7.85e-3)" "prognostic unfavorable (1.86e-4)" "unprognostic (2.12e-1)" "unprognostic (1.71e-1)" "unprognostic (1.14e-1)" "unprognostic (1.23e-1)" "unprognostic (3.75e-2)" "unprognostic (8.35e-2)" 1.5 0.4 0.8 6.6 1.1 12.2 37.3 1.0 1.4 50.1 0.6 37.4 10.7 0.6 6.6 116.6 1.1 0.3 0.5 0.5 0.6 0.3 0.3 0.9 0.1 0.6 0.7 0.2 0.4 0.0 1.2 35.4 0.6 17.9 27.3 0.0 82.2 9.6 0.5 580.3 37.2 1.0 0.5 2.3 19.8 25.4 0.6 42.7 5.1 0.0 19.8 9.9 102.0 0.8 26.3 0.4 1.5 0.2 0.1 0.0 80.6 0.5 0.3 0.1 0.2 0.3 204.3 0.0 5.1 0.3 3.9 463.8 0.7 745.8 0.7 0.0 0.7 0.0 0.3 0.2 0.1 0.0 0.4 0.7 914.1 0.5 783.7 0.2 3.5 0.1 0.1 0.9 0.0 0.0 0.0 0.3 1.7 5.1 2.6 0.0 0.0 0.3 35.9 26.4 0.2 0.3 0.0 0.2 0.9 4.0 0.2 0.0 1.5 0.5 5.0 0.3 5.5 0.1 0.0 0.0 1.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.8 1.1 1.0 1.4 0.5 0.6 0.6 0.7 0.6 0.5 0.6 0.8 1.0 0.0 1.1 0.7 0.3 585.7 17.7 136.0 299.9 0.6 1.7 85.5 1.1 0.0 16.5 0.0 0.0 10.2 0.3 211.5 0.0 0.8 14.2 23.7 2.3 3.7 2.4 0.0 0.1 0.9 18.9 2.4 23.0 8.1 0.0 0.1 0.0 0.0 1.3 0.0 0.2 5.7 6.1 0.0 28.9 3.6 0.3 0.7 33.8 0.0 0.0 0.4 0.0 0.0 0.4 78.8 35.7 0.7 1.4 16.6 108.5 0.1 5.9 0.4 0.0 0.4 3.0 22.7 1.5 31.9 139.4 5.6 1.3 0.1 21.6 10.7 COL4A5 "ASLN, ATS" ENSG00000188153 "Collagen type IV alpha 5 chain" P29400 X 108439838-108697545 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Alport syndrome, Cancer-related genes, Deafness, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 102.9" "Cell type enriched" "Detected in many" 9 "Oligodendrocytes: 713.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 87.7;HHSteC: 95.0;HUVEC TERT2: 92.8;TIME: 88.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA077177 Approved "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "HPA077177: " "unprognostic (2.58e-2)" "unprognostic (2.57e-2)" "unprognostic (3.64e-2)" "unprognostic (3.98e-2)" "unprognostic (1.11e-1)" "unprognostic (1.61e-1)" "unprognostic (1.97e-2)" "unprognostic (7.27e-2)" "unprognostic (2.70e-1)" "unprognostic (2.20e-1)" "unprognostic (1.60e-1)" "unprognostic (1.26e-1)" "prognostic unfavorable (2.41e-5)" "unprognostic (2.10e-3)" "unprognostic (1.70e-1)" "unprognostic (2.61e-2)" "unprognostic (1.06e-1)" 7.4 5.6 25.2 2.3 57.4 0.0 8.1 38.2 40.8 38.1 20.0 5.8 3.8 59.2 25.4 9.6 37.5 18.2 10.9 27.0 33.7 16.9 2.4 8.5 1.2 47.7 43.1 23.0 3.8 16.8 19.7 14.5 47.4 37.0 5.6 6.1 7.4 32.9 7.6 26.4 6.3 47.2 36.4 5.5 34.5 6.0 45.3 2.7 10.5 4.4 1.0 47.6 22.7 102.9 4.5 26.7 47.2 14.9 18.0 10.6 0.3 2.8 11.7 14.2 23.2 24.0 1.9 4.2 0.0 2.0 8.6 21.7 13.2 45.2 17.8 6.7 11.7 3.4 87.7 2.9 95.0 0.0 13.5 49.2 53.6 17.4 37.2 45.2 92.8 0.0 0.2 0.1 13.9 2.0 0.1 0.5 14.0 0.0 16.0 0.1 0.0 0.2 35.9 26.7 0.0 0.0 70.2 2.2 6.0 65.6 12.9 0.0 88.8 9.5 2.8 6.4 4.0 1.9 0.0 0.0 8.2 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 25.2 57.4 38.2 40.8 27.0 33.7 47.7 43.1 47.4 36.4 45.3 102.9 1.0 6.4 7.3 72.5 0.0 26.9 29.7 29.4 17.1 0.5 14.8 14.7 10.0 2.8 14.2 20.2 0.0 0.7 0.0 0.0 0.0 0.4 0.1 7.4 45.4 4.6 0.0 0.0 1.1 0.9 0.4 12.3 3.1 5.7 1.3 2.0 4.2 0.5 0.4 0.0 1.5 0.2 6.1 0.3 2.1 1.7 20.2 0.6 1.8 20.6 0.0 11.1 0.0 3.5 713.9 0.4 0.0 36.9 0.0 18.1 0.0 0.1 8.2 0.6 6.6 2.4 18.3 0.4 0.9 4.2 15.9 0.7 1.1 21.5 0.1 24.7 COL6A2 ENSG00000142173 "Collagen type VI alpha 2 chain" P12110 21 46098112-46132848 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Congenital muscular dystrophy, Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 453.2;Fibroblasts: 1455.4;Leydig cells: 605.5;Peritubular cells: 472.1;Smooth muscle cells: 555.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 4.5;MAIT T-cell: 3.1;memory CD8 T-cell: 2.4;naive CD8 T-cell: 1.2" "Lineage enriched" "Detected in single" 13 "T-cells: 4.5" "Cell line enhanced" "Detected in many" "ASC diff: 1155.7;ASC TERT1: 2116.9;BJ: 1073.7;BJ hTERT+: 982.8;fHDF/TERT166: 775.0;HHSteC: 1129.2;HSkMC: 1524.4;U-138 MG: 1128.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 49.6" "HPA007029, HPA030920, HPA038799" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 8200000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 33: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "HPA007029: AB_1078549, HPA030920: AB_2673659, HPA038799: AB_2676214" "unprognostic (3.53e-1)" "unprognostic (3.76e-2)" "unprognostic (3.20e-2)" "unprognostic (4.87e-2)" "unprognostic (2.92e-2)" "unprognostic (1.38e-1)" "unprognostic (2.39e-1)" "unprognostic (5.28e-3)" "unprognostic (2.11e-2)" "unprognostic (1.68e-2)" "unprognostic (1.56e-1)" "unprognostic (2.01e-1)" "prognostic unfavorable (8.72e-14)" "unprognostic (2.13e-2)" "unprognostic (7.61e-2)" "unprognostic (2.31e-2)" "unprognostic (2.22e-3)" 732.4 96.2 10.1 219.9 10.8 4.5 455.0 8.7 14.4 873.3 21.6 1287.5 97.7 1001.7 36.5 178.8 675.1 283.8 484.3 10.0 14.9 96.5 97.6 394.2 55.7 14.0 19.4 723.6 78.6 24.0 112.2 335.3 11.2 569.9 60.2 0.9 156.2 274.6 123.4 390.6 402.2 275.4 9.8 175.1 441.6 77.0 11.7 35.6 201.3 67.2 25.6 918.6 595.9 12.3 9.4 12.5 34.8 31.2 1155.7 2116.9 10.0 1073.7 982.8 265.5 121.5 2.3 42.4 0.2 79.2 775.0 170.8 0.9 8.1 0.7 21.7 0.8 12.3 0.2 0.2 0.2 1129.2 0.5 4.8 1524.4 0.2 503.6 10.2 0.1 0.6 0.6 0.6 0.8 108.7 5.2 0.4 2.4 19.3 0.0 130.5 0.4 66.9 1.8 0.0 0.1 1.1 54.2 41.6 0.6 0.7 19.4 1.2 6.6 0.2 1128.1 131.5 421.5 270.3 0.7 0.4 0.9 578.1 0.5 164.8 0.0 0.0 0.0 4.5 0.0 3.1 0.0 0.4 2.4 0.0 0.0 0.4 1.2 0.0 0.3 0.0 0.0 0.1 0.5 10.1 10.8 8.7 14.4 10.0 14.9 14.0 19.4 11.2 9.8 11.7 12.3 127.3 3.2 0.6 2.0 3.1 164.4 4.3 0.6 9.1 0.7 12.7 33.5 8.7 4.3 0.6 7.3 0.0 17.6 41.2 0.4 0.0 15.1 4.0 13.2 453.2 101.4 0.0 2.7 0.1 0.4 25.1 1455.4 13.3 10.3 0.0 36.1 123.1 1.4 35.3 0.0 0.8 0.1 0.0 3.1 219.7 23.7 605.5 11.7 181.5 44.0 2.4 3.1 32.0 0.0 0.1 5.9 1.0 472.1 12.1 11.2 0.0 0.4 0.1 0.5 295.9 284.8 555.2 3.7 11.5 4.6 140.4 40.4 32.7 125.3 0.4 3.9 COLQ EAD ENSG00000206561 "Collagen like tail subunit of asymmetric acetylcholinesterase" Q9Y215 3 15450133-15521751 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Neurotransmitter degradation" "Congenital myasthenic syndrome, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 17.9" "Cell type enhanced" "Detected in many" "Astrocytes: 17.3;Excitatory neurons: 45.1;Inhibitory neurons: 46.3;Late spermatids: 16.6;NK-cells: 15.5;Oligodendrocyte precursor cells: 18.1;Oligodendrocytes: 18.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "MAIT T-cell: 60.9" "Lineage enriched" "Detected in many" 34 "T-cells: 60.9" "Group enriched" "Detected in some" 6 "BEWO: 11.5;HDLM-2: 3.8;U-937: 5.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA045876 Approved "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA045876: AB_2679479" "unprognostic (4.08e-3)" "unprognostic (2.61e-2)" "unprognostic (2.13e-3)" "unprognostic (2.37e-1)" "unprognostic (2.11e-1)" "unprognostic (4.62e-2)" "unprognostic (1.27e-2)" "unprognostic (1.15e-1)" "unprognostic (1.52e-1)" "unprognostic (1.99e-1)" "unprognostic (1.28e-3)" "unprognostic (4.68e-1)" "unprognostic (7.00e-5)" "unprognostic (6.58e-2)" "unprognostic (1.97e-1)" "unprognostic (1.05e-1)" "unprognostic (1.30e-4)" 2.5 2.3 3.1 0.7 3.2 0.8 2.2 3.9 4.6 4.6 11.9 3.7 1.0 3.4 1.6 0.9 8.8 1.1 17.9 3.7 2.7 2.9 3.4 2.5 3.9 4.8 3.2 3.6 1.7 3.6 5.7 0.3 2.8 4.6 0.5 0.6 1.5 0.8 10.8 1.6 2.6 0.7 2.6 7.2 2.4 5.0 2.3 2.6 2.6 5.1 3.0 2.2 2.4 2.9 0.1 0.0 0.7 0.0 0.0 0.3 11.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 3.8 0.4 0.2 0.5 0.0 0.0 0.1 0.3 0.4 0.0 0.3 0.1 0.2 0.3 0.5 0.0 0.3 0.2 0.2 0.1 0.3 0.0 0.0 0.5 0.2 0.1 0.1 0.1 0.0 0.2 1.0 0.0 0.0 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.2 0.1 0.8 0.4 0.0 0.0 5.2 0.1 0.0 0.6 0.0 9.9 0.0 60.9 0.0 5.3 7.4 0.0 0.0 0.5 0.6 0.0 1.8 0.0 0.4 0.3 3.5 3.1 3.2 3.9 4.6 3.7 2.7 4.8 3.2 2.8 2.6 2.3 2.9 0.6 0.0 0.6 17.3 0.5 0.3 0.2 0.1 0.0 0.3 0.4 0.6 0.7 0.0 1.4 0.0 0.0 0.3 7.7 0.0 0.0 0.1 4.1 6.5 1.4 0.4 1.2 0.4 45.1 0.0 0.2 0.6 1.1 0.8 0.0 3.3 1.8 0.8 0.2 6.7 46.3 0.2 2.0 0.6 0.0 16.6 1.8 0.4 0.0 7.5 0.4 0.3 15.5 18.1 18.3 0.2 0.1 4.5 2.0 0.2 0.0 0.2 4.3 0.7 0.0 0.5 0.7 1.5 0.5 0.0 0.1 2.3 4.1 1.4 0.3 0.1 COQ7 "CAT5, CLK-1" ENSG00000167186 "Coenzyme Q7, hydroxylase" Q99807 16 19067614-19080095 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Ubiquinone biosynthesis" "Monooxygenase, Oxidoreductase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 40.4;neutrophil: 126.5" "Lineage enriched" "Detected in all" 8 "granulocytes: 126.5" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA067252, HPA071922" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 8: Non-specific - Mitochondria" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Nucleoplasm "HPA067252: AB_2685813, HPA071922: AB_2686473" "unprognostic (1.37e-1)" "unprognostic (6.89e-3)" "unprognostic (1.59e-2)" "unprognostic (6.08e-2)" "unprognostic (2.44e-2)" "unprognostic (9.03e-2)" "unprognostic (1.31e-1)" "unprognostic (4.42e-2)" "unprognostic (1.15e-1)" "unprognostic (7.27e-3)" "unprognostic (2.15e-1)" "unprognostic (8.32e-2)" "prognostic favorable (8.23e-12)" "unprognostic (2.19e-1)" "unprognostic (2.76e-1)" "unprognostic (3.14e-2)" "unprognostic (5.27e-2)" 10.2 13.6 10.7 7.0 11.2 4.8 13.4 10.9 11.6 10.8 12.5 14.1 12.4 15.6 12.3 12.4 15.5 10.7 23.4 11.0 10.8 14.1 12.3 10.0 8.3 10.6 11.3 20.0 10.3 24.4 9.7 10.0 11.1 17.7 13.2 14.0 10.4 14.7 45.8 7.9 11.8 11.6 10.4 10.0 12.8 20.9 11.3 10.3 16.2 44.9 8.4 10.3 8.8 13.1 23.5 24.8 21.1 12.4 11.6 12.2 17.7 13.5 11.0 18.0 18.5 15.9 19.1 17.8 63.9 10.4 19.4 24.5 29.6 16.9 13.0 15.2 29.9 9.5 22.8 49.3 14.4 22.9 20.1 10.3 14.6 16.8 12.2 14.8 14.8 20.9 26.4 16.2 12.9 42.4 24.0 18.4 16.1 9.1 13.1 29.0 23.3 22.8 15.7 15.5 30.4 17.4 12.6 27.4 16.2 10.2 25.2 30.7 16.3 19.0 10.9 14.1 19.7 15.0 26.2 19.7 20.4 13.1 12.5 40.4 11.4 17.8 9.9 10.6 9.4 16.3 8.9 8.7 12.6 15.3 12.2 10.8 126.5 12.9 12.3 15.6 6.2 5.6 10.7 11.2 10.9 11.6 11.0 10.8 10.6 11.3 11.1 10.4 11.3 13.1 13.3 16.0 12.6 6.2 35.5 11.0 26.3 20.9 13.6 31.2 18.3 21.1 21.8 31.5 14.9 16.5 39.6 21.2 28.7 38.1 45.0 25.2 14.8 23.7 16.2 16.1 24.0 4.8 6.0 18.0 17.9 14.9 32.1 23.2 25.4 31.1 20.7 11.1 23.3 20.2 8.8 39.0 30.5 29.4 12.9 8.5 18.6 18.8 10.6 4.7 11.6 39.5 8.2 5.0 9.4 13.2 30.4 13.9 11.6 17.8 71.5 23.7 24.4 53.9 19.7 20.0 20.2 81.3 53.1 12.8 12.4 32.2 23.9 38.2 39.8 24.0 CORO1B coronin-2 ENSG00000172725 "Coronin 1B" Q9BR76 11 67435510-67443821 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 301.4;Paneth cells: 324.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 221.8" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017616, HPA040113, HPA070456" Enhanced Supported "Plasma membrane,Cytosol" NA NA 960000 "Cluster 51: Monocytes - Innate immune response" "Cluster 4: Stomach - Digestion" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB017616: AB_2087018, HPA040113: AB_2676850, HPA070456: AB_2686268" "unprognostic (1.94e-1)" "unprognostic (2.40e-1)" "unprognostic (3.21e-1)" "prognostic favorable (1.65e-4)" "unprognostic (1.02e-1)" "unprognostic (8.23e-3)" "unprognostic (1.49e-3)" "unprognostic (7.22e-2)" "unprognostic (1.86e-1)" "unprognostic (4.86e-2)" "unprognostic (1.48e-1)" "unprognostic (3.88e-2)" "unprognostic (8.58e-3)" "unprognostic (1.85e-1)" "unprognostic (1.04e-1)" "unprognostic (1.21e-2)" "unprognostic (6.64e-3)" 54.4 56.4 20.2 29.7 23.8 20.3 53.4 23.4 27.0 55.7 21.1 70.2 62.9 72.8 14.6 80.2 54.2 44.1 26.1 19.4 22.7 48.2 47.2 53.7 41.9 28.0 23.6 42.7 52.5 24.6 35.1 31.2 25.1 71.0 34.5 6.6 73.2 39.6 13.0 42.4 62.3 36.7 24.2 66.0 77.1 13.9 25.1 21.1 55.8 9.9 18.4 58.3 53.5 26.3 80.9 81.4 37.5 76.0 94.1 81.3 56.6 58.5 118.0 94.2 70.8 134.1 116.0 6.4 111.3 80.8 95.8 67.9 41.9 74.9 16.8 19.4 40.7 54.9 47.3 57.9 148.1 2.3 120.8 110.6 66.3 80.1 37.2 59.7 120.7 49.4 42.7 9.2 54.2 238.4 14.4 11.2 47.7 198.2 73.4 11.2 41.0 14.9 62.6 104.3 40.7 50.8 52.4 139.6 181.6 26.0 178.5 63.0 92.2 63.4 47.4 87.4 35.2 1.6 3.3 14.6 103.4 8.2 66.4 57.3 102.8 8.0 10.9 212.9 8.3 20.0 37.6 14.6 79.0 11.0 21.2 11.4 47.8 11.9 221.8 60.8 55.2 57.8 20.2 23.8 23.4 27.0 19.4 22.7 28.0 23.6 25.1 24.2 25.1 26.3 58.7 3.2 2.2 4.6 53.4 27.9 60.1 90.8 40.9 13.0 53.8 39.0 1.6 50.1 66.4 47.8 8.4 87.8 39.2 301.4 60.7 111.4 8.9 43.6 32.9 52.0 99.0 19.8 1.8 105.0 229.8 35.8 111.1 64.8 28.0 46.7 47.8 22.4 251.8 15.2 2.4 188.6 81.4 138.6 66.4 5.0 39.4 96.3 71.2 10.3 195.3 30.0 41.2 4.5 6.8 136.9 324.9 34.6 64.3 55.6 263.5 84.0 41.2 14.6 52.6 22.1 55.1 8.1 6.6 47.6 31.0 150.5 100.3 54.8 128.0 74.5 CORO2A "IR10, WDR2" ENSG00000106789 "Coronin 2A" Q92828 9 98120975-98192637 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 35.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 76.2;Proximal enterocytes: 93.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 6 "granulocytes: 11.4;monocytes: 7.8;T-cells: 11.9" "Cell line enhanced" "Detected in many" "BEWO: 66.6;OE19: 56.4;SK-BR-3: 45.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041161, HPA041302" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 28: BEWO - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA041161: AB_10795537, HPA041302: AB_10794195" "unprognostic (4.49e-3)" "unprognostic (3.44e-2)" "unprognostic (3.14e-1)" "unprognostic (1.78e-1)" "unprognostic (3.39e-3)" "unprognostic (1.64e-1)" "unprognostic (3.73e-2)" "unprognostic (5.73e-2)" "unprognostic (2.79e-1)" "unprognostic (1.52e-1)" "unprognostic (4.50e-3)" "unprognostic (2.85e-1)" "prognostic unfavorable (6.56e-4)" "unprognostic (4.16e-2)" "unprognostic (1.40e-2)" "unprognostic (1.87e-2)" "unprognostic (6.40e-3)" 1.9 1.7 1.9 4.9 1.5 14.8 4.7 4.9 3.2 6.1 0.0 17.5 34.3 1.6 0.7 15.2 4.7 18.2 0.3 1.2 2.9 1.1 3.3 7.4 2.9 3.7 3.4 0.3 0.4 2.5 4.0 2.1 4.9 14.3 12.9 1.2 6.1 1.4 0.3 9.3 35.1 2.2 0.8 3.0 11.1 9.2 4.5 5.7 1.2 0.3 5.9 12.8 7.7 1.8 8.4 2.9 0.6 2.0 1.2 1.3 66.6 0.6 0.7 2.1 3.2 19.1 1.4 0.1 9.4 1.2 3.2 23.1 7.7 12.7 1.3 6.9 1.8 0.2 11.6 17.1 2.7 7.9 0.7 0.4 15.4 1.0 18.6 0.7 0.7 10.0 6.8 3.8 0.3 6.3 1.5 7.8 8.6 56.4 2.2 6.1 0.1 0.2 1.3 23.5 1.7 2.4 4.4 45.3 1.6 15.0 5.3 12.8 0.6 0.2 9.7 0.2 2.4 0.7 4.0 0.7 0.5 2.5 2.8 11.2 1.4 11.4 2.4 2.9 5.2 0.6 3.9 3.7 0.5 0.5 2.5 3.3 1.0 1.7 7.8 0.7 11.9 1.5 1.9 1.5 4.9 3.2 1.2 2.9 3.7 3.4 4.9 0.8 4.5 1.8 2.8 12.8 27.8 0.7 3.1 6.6 18.9 47.2 14.8 2.1 8.5 4.3 1.9 28.6 46.4 0.0 4.2 10.5 2.1 76.2 0.0 4.5 2.6 15.6 11.6 6.0 7.2 0.8 11.6 5.1 42.2 2.2 36.2 19.9 0.0 38.1 0.7 3.8 6.0 1.7 10.5 15.7 20.3 12.0 2.6 3.9 0.0 10.6 0.0 1.0 1.8 0.7 2.1 0.5 0.8 22.6 19.7 0.4 1.4 15.7 93.0 1.7 35.8 1.7 0.0 1.5 3.7 0.5 3.3 29.4 9.9 15.9 10.7 0.2 36.3 30.4 CORO2B "ClipinC, KIAA0925" ENSG00000103647 "Coronin 2B" Q9UQ03 15 68578993-68727806 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 83.4;retina: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 57.1;Bipolar cells: 43.2;Cone photoreceptor cells: 37.5;Excitatory neurons: 96.6;Inhibitory neurons: 50.0;Oligodendrocytes: 146.4" "Group enriched" "Detected in many" 8 "glioma: 34.7;melanoma: 21.5" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.2" "Lineage enriched" "Detected in single" 13 "B-cells: 1.2" "Cell line enhanced" "Detected in many" "ASC diff: 26.8;ASC TERT1: 57.5;HSkMC: 41.6;hTEC/SVTERT24-B: 34.6;U-87 MG: 59.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017960 Enhanced Supported Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 37: B-cells - Transcription" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Focal adhesion sites" "HPA017960: AB_1847167" "unprognostic (1.35e-1)" "unprognostic (2.63e-2)" "unprognostic (2.81e-3)" "unprognostic (4.71e-3)" "unprognostic (3.28e-1)" "unprognostic (8.11e-5)" "unprognostic (4.77e-2)" "unprognostic (1.24e-1)" "unprognostic (3.68e-2)" "unprognostic (1.81e-1)" "unprognostic (1.33e-3)" "unprognostic (4.12e-2)" "unprognostic (1.26e-1)" "unprognostic (1.10e-2)" "unprognostic (5.83e-2)" "unprognostic (3.59e-2)" "unprognostic (1.87e-2)" 10.9 3.5 44.1 2.0 60.9 0.7 7.2 62.1 66.5 7.2 28.2 5.9 1.2 7.5 2.2 1.4 27.5 4.7 16.4 48.1 43.5 9.2 1.3 5.1 1.8 62.4 62.7 14.9 2.2 0.5 3.5 3.2 58.0 4.3 1.5 45.2 2.7 4.9 2.6 4.1 2.8 6.3 51.9 3.9 3.1 1.0 66.5 1.3 6.1 4.5 0.8 4.1 3.7 83.4 0.6 0.8 26.2 2.2 26.8 57.5 0.0 13.7 15.0 2.3 3.2 0.3 3.0 3.5 1.6 2.3 3.7 0.2 1.0 0.3 9.5 0.0 1.2 0.0 0.0 1.2 9.8 0.0 0.4 41.6 0.3 34.6 2.0 20.4 1.0 0.0 0.0 0.1 24.4 0.1 0.0 0.1 6.5 0.0 0.1 2.2 0.1 1.2 3.7 0.0 15.3 0.3 0.2 0.0 7.8 4.8 0.0 3.1 0.2 7.8 8.9 1.7 18.3 0.0 0.0 3.5 59.2 0.0 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 44.1 60.9 62.1 66.5 48.1 43.5 62.4 62.7 58.0 51.9 66.5 83.4 2.8 0.0 0.0 57.1 1.1 1.0 0.4 0.0 0.0 43.2 0.1 1.0 1.5 0.0 0.0 7.3 37.5 0.0 0.0 0.0 0.0 3.8 0.4 2.1 11.6 3.0 3.6 0.0 96.6 0.6 0.0 8.0 0.0 0.3 0.0 0.9 6.4 0.0 0.2 0.0 50.0 0.3 0.0 0.3 0.7 0.7 7.8 0.3 7.2 11.2 0.1 12.5 0.0 17.1 146.4 0.6 0.0 0.4 0.0 0.1 0.0 0.1 8.1 21.4 6.6 1.4 2.1 0.2 0.5 0.1 0.9 0.0 0.1 7.5 0.0 0.1 CPNE9 KIAA4217 ENSG00000144550 "Copine family member 9" Q8IYJ1 3 9703826-9729908 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 13 "brain: 69.2" "Cell type enhanced" "Detected in some" "Early spermatids: 12.9;Excitatory neurons: 28.2;Inhibitory neurons: 8.0;Late spermatids: 61.3" "Cancer enriched" "Detected in single" 4 "testis cancer: 1.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "intermediate monocyte: 1.0" "Lineage enhanced" "Detected in single" "monocytes: 1.0" "Cell line enhanced" "Detected in some" "Daudi: 2.3;U-937: 2.0" "Low region specificity" "Detected in all" HPA060813 Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA060813: " "unprognostic (2.96e-1)" "unprognostic (4.75e-2)" "unprognostic (1.34e-1)" "unprognostic (5.04e-3)" "unprognostic (1.10e-1)" "unprognostic (1.96e-1)" "unprognostic (2.13e-3)" "unprognostic (1.03e-2)" "unprognostic (3.19e-2)" "unprognostic (1.06e-1)" "unprognostic (1.20e-4)" "unprognostic (2.67e-2)" "unprognostic (5.44e-4)" "unprognostic (1.47e-2)" "unprognostic (8.59e-2)" "unprognostic (3.45e-1)" "unprognostic (7.48e-2)" 0.1 2.1 10.9 0.2 7.1 1.2 0.1 12.1 23.6 0.1 0.0 0.4 0.3 0.1 0.0 0.1 0.1 0.1 0.1 5.8 19.6 0.2 0.0 0.3 0.2 69.2 19.8 0.1 0.1 0.1 5.3 0.1 65.0 0.1 0.1 1.1 0.1 0.2 0.0 1.7 0.3 0.2 4.2 0.2 0.3 1.3 39.6 0.1 0.1 0.0 0.1 0.1 0.1 12.9 0.0 0.3 0.1 0.0 0.3 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.1 2.3 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.2 0.7 0.2 0.0 0.0 0.2 0.3 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.2 0.6 0.5 0.0 0.0 0.2 0.4 0.7 0.9 0.0 0.0 0.0 0.3 0.0 0.1 0.7 0.4 0.3 2.0 0.1 0.0 0.3 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.4 0.0 0.1 10.9 7.1 12.1 23.6 5.8 19.6 69.2 19.8 65.0 4.2 39.6 12.9 0.1 0.0 0.0 2.0 0.0 0.3 0.0 0.0 0.6 0.8 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 12.9 0.1 0.1 0.1 0.0 0.0 28.2 0.2 0.0 0.3 0.0 0.4 0.0 0.0 0.4 0.0 1.9 0.0 8.0 0.0 0.0 0.8 0.3 61.3 0.0 0.8 0.0 3.7 0.0 0.7 0.0 2.0 2.2 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.2 0.2 0.9 0.7 0.2 0.4 0.0 0.1 0.0 0.1 0.0 CPPED1 "CSTP1, FLJ11151" ENSG00000103381 "Calcineurin like phosphoesterase domain containing 1" Q9BRF8 16 12659799-12803887 "Enzymes, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cytotrophoblasts: 105.2;monocytes: 127.4;Syncytiotrophoblasts: 131.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 674.2" "Group enriched" "Detected in all" 28 "dendritic cells: 168.5;granulocytes: 674.2;monocytes: 320.8" "Cell line enhanced" "Detected in many" "Hep G2: 144.2;HMC-1: 129.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040938, HPA041970" Uncertain Supported "Plasma membrane,Cytosol" No No 470000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA040938: AB_10673443, HPA041970: AB_2677774" "prognostic unfavorable (9.72e-4)" "unprognostic (1.70e-1)" "unprognostic (2.04e-3)" "unprognostic (1.05e-2)" "unprognostic (1.13e-3)" "unprognostic (3.86e-2)" "unprognostic (1.35e-1)" "unprognostic (8.67e-2)" "unprognostic (1.23e-1)" "unprognostic (3.26e-2)" "unprognostic (6.26e-2)" "unprognostic (3.64e-1)" "prognostic favorable (1.62e-9)" "unprognostic (5.05e-2)" "unprognostic (1.25e-1)" "unprognostic (2.48e-3)" "unprognostic (2.40e-2)" 12.5 9.4 9.1 19.3 14.1 14.0 8.2 13.0 11.4 11.0 7.3 13.3 21.3 7.9 5.1 25.2 7.1 11.2 10.1 8.3 13.3 33.7 34.4 13.7 11.7 14.0 13.1 7.6 4.8 3.9 4.1 18.5 14.4 11.1 14.8 3.7 13.1 8.6 8.2 6.5 21.4 12.9 11.3 29.8 8.7 15.5 12.2 9.2 13.2 9.6 16.6 11.5 8.8 17.3 5.0 29.7 3.3 7.7 12.0 25.3 0.5 54.1 14.5 28.4 23.1 14.5 15.2 7.3 54.6 39.6 12.5 0.4 0.0 13.5 29.3 17.0 8.2 62.5 4.2 144.2 7.4 0.1 129.9 25.4 3.0 2.5 20.2 0.1 43.1 9.9 22.1 4.3 70.4 6.3 5.6 29.1 8.7 2.4 4.2 11.9 18.8 15.6 43.0 9.4 15.3 10.0 0.2 48.5 20.0 15.3 10.5 13.7 65.0 40.6 8.5 0.2 0.1 0.1 1.0 11.6 9.1 31.7 8.8 57.1 224.0 146.1 9.1 320.0 7.8 10.8 7.6 10.0 168.5 8.4 2.4 5.7 674.2 13.5 320.8 41.1 13.8 129.7 9.1 14.1 13.0 11.4 8.3 13.3 14.0 13.1 14.4 11.3 12.2 17.3 12.3 9.6 16.7 8.1 8.7 4.6 3.4 4.9 4.6 3.3 4.7 4.7 10.7 10.0 11.4 14.7 8.4 105.2 18.5 9.2 60.7 43.1 3.6 5.3 13.5 16.7 6.0 31.7 13.1 12.8 15.6 12.6 4.1 9.4 54.4 8.1 7.5 45.8 47.1 10.1 10.2 9.3 6.1 80.3 30.7 4.1 15.5 59.0 7.2 30.0 127.4 13.5 8.2 21.1 70.9 31.9 18.3 24.0 4.4 3.2 40.6 66.0 13.4 6.1 26.3 17.6 11.9 2.5 9.9 14.8 4.5 131.9 8.3 13.6 15.4 1.7 CRCP "C17, CGRP-RCP, POLR3I, RCP, RCP9" ENSG00000241258 "CGRP receptor component" O75575 7 66114604-66154568 "Metabolic proteins, Predicted intracellular proteins" "Antiviral defense, Immunity, Innate immunity, Transcription" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006883, HPA007216" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA006883: , HPA007216: AB_1856160" "unprognostic (2.36e-2)" "unprognostic (4.43e-1)" "unprognostic (2.32e-3)" "unprognostic (1.42e-3)" "unprognostic (3.38e-2)" "unprognostic (6.26e-2)" "unprognostic (2.67e-3)" "unprognostic (8.17e-2)" "unprognostic (1.77e-3)" "unprognostic (2.59e-3)" "unprognostic (8.49e-2)" "unprognostic (9.35e-2)" "unprognostic (1.39e-3)" "unprognostic (3.87e-2)" "unprognostic (4.81e-1)" "unprognostic (3.50e-1)" "unprognostic (2.06e-1)" 13.5 15.3 10.8 13.8 11.4 37.5 17.6 12.7 14.1 14.7 11.2 18.3 16.8 14.7 11.3 20.0 17.3 13.1 17.5 11.3 13.7 16.5 26.5 14.5 16.4 11.6 12.2 16.9 20.6 21.2 11.1 13.7 14.1 17.3 19.6 14.2 16.1 15.8 14.8 16.1 14.7 18.2 11.3 17.4 17.9 8.3 13.9 15.2 20.0 13.6 16.6 16.6 14.4 12.4 44.0 26.9 19.5 26.4 27.0 33.7 19.0 29.9 31.9 43.7 33.7 43.5 34.6 40.6 35.7 29.0 37.0 32.4 26.7 35.9 46.1 26.0 27.3 23.1 19.1 20.9 19.4 47.6 32.6 27.0 30.9 38.3 71.6 27.8 23.7 23.1 49.3 28.8 30.0 35.0 36.7 37.7 39.8 58.7 33.6 38.4 30.1 37.8 27.8 40.5 46.1 60.3 34.3 95.2 29.2 22.8 73.6 24.0 27.6 63.4 33.6 36.5 56.3 35.4 70.0 54.3 35.9 36.8 51.6 25.9 12.0 20.4 17.6 11.1 17.1 14.4 15.4 14.9 9.1 13.4 14.5 17.3 20.9 10.9 17.0 12.0 16.0 12.0 10.8 11.4 12.7 14.1 11.3 13.7 11.6 12.2 14.1 11.3 13.9 12.4 24.8 28.9 32.5 12.1 30.4 13.4 22.2 13.9 24.5 29.9 19.7 19.2 25.7 12.8 23.0 16.5 22.9 12.6 47.8 15.5 35.2 21.3 4.4 27.7 30.3 18.1 16.1 12.2 19.5 24.8 11.8 20.5 27.5 29.4 34.1 22.8 9.7 25.2 12.1 30.3 20.5 15.4 8.2 13.6 9.2 4.3 18.6 17.7 16.0 12.2 20.6 23.0 22.6 12.5 17.2 29.8 10.2 22.2 26.5 26.2 10.5 17.6 32.8 25.8 6.6 27.2 18.5 24.5 16.7 20.9 14.8 11.5 27.3 28.6 14.7 32.1 CRLF3 "CREME9, CYTOR4" ENSG00000176390 "Cytokine receptor like factor 3" Q8IUI8 17 30769388-30824692 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 35.5" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007596 Enhanced Approved "Plasma membrane,Cytosol" NA NA 210000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA007596: AB_1847241" "unprognostic (1.02e-1)" "unprognostic (9.79e-2)" "unprognostic (7.12e-2)" "unprognostic (9.65e-2)" "unprognostic (2.28e-1)" "unprognostic (1.55e-1)" "unprognostic (2.52e-2)" "unprognostic (9.22e-2)" "unprognostic (1.00e-2)" "unprognostic (3.10e-2)" "unprognostic (5.81e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.31e-7)" "unprognostic (3.35e-1)" "unprognostic (2.40e-2)" "unprognostic (1.84e-1)" "unprognostic (6.51e-2)" 7.5 4.9 3.5 21.5 3.2 20.6 7.0 10.5 4.4 7.6 0.2 7.8 6.1 5.3 2.8 12.8 4.9 7.5 4.3 4.5 2.7 4.2 5.4 9.1 35.5 1.8 1.9 4.3 4.4 7.9 4.7 12.6 2.4 4.7 7.9 9.5 5.9 3.8 3.8 11.1 9.7 6.5 1.3 23.4 6.6 10.3 3.7 33.4 4.3 4.4 32.7 11.0 8.0 3.0 11.3 12.2 7.5 15.6 13.4 10.3 11.1 10.4 10.1 19.8 20.6 13.5 7.4 36.8 15.2 13.0 19.3 19.2 12.8 8.6 23.6 17.6 23.3 15.7 9.9 10.3 7.4 21.0 11.2 6.1 11.8 16.0 13.4 7.4 19.4 32.9 40.1 37.6 12.6 6.8 46.6 21.8 14.9 18.7 7.4 20.0 24.2 22.2 13.1 9.4 5.3 12.5 10.6 16.1 11.6 15.6 12.5 10.3 10.4 11.4 13.9 18.5 25.8 15.7 14.2 24.9 10.9 16.6 12.9 53.7 57.9 139.9 37.0 59.5 39.3 46.7 52.2 42.4 43.0 46.8 99.9 75.6 117.3 40.3 72.1 22.0 63.7 84.5 3.5 3.2 10.5 4.4 4.5 2.7 1.8 1.9 2.4 1.3 3.7 3.0 10.4 0.0 12.5 17.6 50.9 22.6 8.0 5.4 16.5 17.9 7.0 4.3 4.5 2.8 4.6 7.3 14.6 18.7 36.2 9.2 5.9 5.1 13.5 6.1 8.4 10.6 3.6 46.9 54.8 5.3 17.6 7.7 13.3 9.1 22.8 5.5 8.9 4.2 16.8 6.7 56.5 3.9 8.2 26.1 25.0 21.3 6.5 26.7 5.4 42.2 39.9 4.7 47.4 38.7 38.0 9.1 3.4 4.1 25.7 8.4 2.6 5.3 8.9 25.2 13.1 9.2 7.5 27.5 27.3 11.4 27.8 45.8 47.1 5.3 4.2 7.8 CROCC "ROLT, rootletin" ENSG00000058453 "Ciliary rootlet coiled-coil, rootletin" Q5TZA2 1 16740273-16972964 "Predicted intracellular proteins" "Cell cycle, Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 109.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021191, HPA021762" Enhanced Supported "Plasma membrane,Centrosome" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Centrosome" "HPA021191: AB_1856395, HPA021762: AB_1856396" "unprognostic (9.07e-3)" "unprognostic (9.03e-2)" "unprognostic (6.04e-2)" "prognostic favorable (8.34e-5)" "unprognostic (3.27e-1)" "unprognostic (1.25e-3)" "unprognostic (1.42e-3)" "prognostic favorable (7.92e-4)" "unprognostic (2.05e-1)" "unprognostic (7.75e-2)" "unprognostic (3.36e-3)" "unprognostic (5.75e-2)" "prognostic unfavorable (7.97e-4)" "unprognostic (1.58e-1)" "unprognostic (9.83e-2)" "unprognostic (6.05e-2)" "unprognostic (1.76e-3)" 7.6 7.6 5.2 2.3 5.5 1.6 8.0 10.1 7.2 13.5 29.0 10.2 1.7 10.4 0.7 10.0 22.7 1.4 6.2 5.8 6.2 8.3 3.3 8.4 2.4 9.5 11.5 13.3 10.7 1.7 10.2 1.3 6.1 10.4 0.4 11.3 7.6 1.8 6.2 14.3 7.9 1.1 6.2 10.2 8.9 5.3 6.6 2.8 8.1 1.2 0.7 9.2 11.4 6.9 4.1 1.7 3.1 3.1 2.1 1.9 1.2 2.9 0.9 0.9 1.0 0.2 1.8 10.9 2.7 1.3 0.3 4.9 0.7 2.2 0.1 0.9 5.6 5.0 6.1 0.8 3.7 0.3 4.9 1.7 5.0 0.9 0.8 1.7 1.5 7.7 0.7 2.7 0.3 3.5 3.4 1.2 11.1 0.9 2.6 3.1 4.1 3.8 0.7 1.1 9.4 10.2 3.1 2.0 9.7 0.9 4.1 1.4 4.3 2.6 3.4 6.8 2.3 4.7 3.7 2.2 2.6 0.7 3.3 0.0 0.0 0.3 0.3 0.1 0.5 0.1 0.2 0.2 0.0 0.3 0.2 0.1 0.0 0.3 0.0 0.1 0.3 0.1 5.2 5.5 10.1 7.2 5.8 6.2 9.5 11.5 6.1 6.2 6.6 6.9 9.0 0.0 4.6 14.0 5.4 6.2 4.1 4.4 17.1 26.3 7.9 7.7 5.8 5.7 4.1 5.5 27.1 1.3 8.2 2.3 0.0 4.7 5.5 35.2 6.3 7.1 3.6 2.5 27.9 2.3 6.5 11.3 6.1 5.9 1.3 28.2 6.4 1.8 2.4 3.3 24.0 4.3 4.1 1.6 5.3 2.6 19.3 3.4 5.4 11.2 3.1 11.7 12.3 13.0 19.9 2.4 1.9 12.8 2.1 2.0 0.8 1.5 34.0 109.7 0.0 12.8 9.4 1.2 12.8 13.1 5.1 1.1 8.0 3.5 2.7 2.2 CRYAB "CRYA2, HSPB5" ENSG00000109846 "Crystallin alpha B" P02511 11 111908564-111923722 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Chaperone, Eye lens protein" "Cancer-related genes, Cardiomyopathy, Cataract, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 5623.2;heart muscle: 10683.1;skeletal muscle: 6972.0;tongue: 9406.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 2889.5;Cardiomyocytes: 6878.2;Muller glia cells: 1664.3;Proximal tubular cells: 7285.9" "Group enriched" "Detected in all" 6 "glioma: 426.4;renal cancer: 575.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 6 "ASC diff: 2663.1;fHDF/TERT166: 775.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002053, CAB040560, HPA057100" Enhanced Enhanced "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 370000 "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB002053: AB_442024, CAB040560: , HPA057100: AB_2683337" "unprognostic (1.06e-2)" "unprognostic (2.26e-1)" "prognostic unfavorable (4.90e-5)" "unprognostic (2.46e-2)" "unprognostic (3.02e-2)" "unprognostic (8.41e-3)" "unprognostic (9.29e-3)" "unprognostic (7.35e-2)" "unprognostic (8.91e-2)" "unprognostic (1.55e-2)" "unprognostic (6.68e-2)" "unprognostic (7.02e-2)" "unprognostic (3.68e-2)" "unprognostic (7.92e-2)" "unprognostic (8.83e-2)" "unprognostic (1.18e-1)" "prognostic unfavorable (1.70e-5)" 1035.0 106.6 2466.0 113.9 3113.8 0.4 592.2 3032.2 5623.2 439.1 2077.7 678.9 24.6 351.4 179.1 312.2 204.0 71.7 10683.1 2424.9 2666.2 2123.2 37.2 253.4 15.0 3215.2 2856.7 136.0 50.6 24.9 209.2 107.8 3147.1 317.9 78.2 478.7 428.7 358.5 6972.0 317.3 158.5 338.1 2877.3 88.5 263.8 23.5 2815.5 20.9 477.7 9406.7 34.4 490.0 477.5 4060.6 0.1 0.5 0.1 45.0 2663.1 90.9 15.0 54.5 2.5 0.8 2.5 1.7 0.2 0.0 41.7 775.8 0.2 2.0 1.8 2.3 1.4 0.3 0.0 0.0 11.9 3.9 16.9 0.4 0.7 77.1 11.1 0.6 6.2 44.3 0.2 0.0 4.6 2.5 169.5 0.1 0.1 1.1 0.5 0.0 1.0 0.2 0.0 0.6 29.8 0.8 0.1 0.4 5.3 9.1 39.8 63.5 4.9 0.0 1.7 310.1 105.0 6.5 4.1 0.5 0.1 0.6 7.1 0.4 39.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2466.0 3113.8 3032.2 5623.2 2424.9 2666.2 3215.2 2856.7 3147.1 2877.3 2815.5 4060.6 38.4 83.3 4.1 96.0 51.3 174.9 2889.5 32.1 72.8 16.2 334.4 696.1 6878.2 84.4 15.2 1338.9 18.8 3.9 6.8 0.4 677.0 320.3 24.7 345.4 265.3 88.4 7.1 0.0 6.7 11.5 7.4 880.6 0.0 1008.4 0.0 16.1 35.7 0.7 5.8 10.1 12.6 2.4 8.2 0.3 85.8 12.6 228.6 67.7 483.8 11.2 3.6 1664.3 0.0 7.5 615.7 12.1 0.0 187.7 1.6 855.4 0.0 7285.9 23.2 59.4 138.1 799.9 1053.3 21.6 1.4 56.5 155.1 33.4 55.4 6.7 1.2 249.0 CSDE1 "D1S155E, UNR" ENSG00000009307 "Cold shock domain containing E1" O75534 1 114716913-114758676 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" RNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 1408.6" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "MCF7: 2403.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018846, HPA052221" Supported Enhanced "Plasma membrane,Cytosol" NA NA 100000 "Cluster 18: Basophils - Vesicular transport" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA018846: AB_1847266, HPA052221: AB_2681767" "unprognostic (2.84e-1)" "unprognostic (9.18e-3)" "unprognostic (4.86e-3)" "unprognostic (3.30e-3)" "unprognostic (2.83e-2)" "unprognostic (4.51e-2)" "unprognostic (5.32e-3)" "unprognostic (5.16e-2)" "unprognostic (1.78e-1)" "unprognostic (5.19e-2)" "unprognostic (3.24e-2)" "unprognostic (2.40e-1)" "unprognostic (4.69e-2)" "unprognostic (4.67e-2)" "unprognostic (1.18e-1)" "unprognostic (5.17e-3)" "unprognostic (2.54e-2)" 412.5 166.8 149.0 170.9 168.8 276.4 241.9 160.5 170.8 193.8 163.5 300.1 187.3 226.7 196.2 247.2 162.9 172.0 414.8 137.6 169.8 228.2 233.6 182.8 172.4 166.4 169.5 258.8 216.2 273.8 85.8 182.4 172.6 229.8 199.6 177.6 230.0 245.6 1408.6 201.6 196.1 236.4 172.2 176.5 201.7 257.4 164.7 218.8 262.6 1039.4 208.2 238.4 137.0 187.3 658.8 226.6 395.5 396.1 440.7 561.4 550.1 566.7 420.5 373.0 301.1 334.0 193.7 514.9 465.6 543.1 217.0 272.3 442.4 439.6 539.2 632.1 302.8 506.1 390.3 299.9 388.2 380.7 288.7 414.7 468.2 447.0 583.2 502.2 433.5 426.5 523.3 327.3 458.9 2403.4 513.8 242.0 755.0 274.0 302.5 378.4 1221.9 244.0 295.4 508.4 485.6 320.7 553.9 455.8 433.3 411.9 234.5 599.4 526.9 437.8 597.3 579.6 629.1 495.7 587.9 567.7 564.9 422.2 1365.1 217.2 241.4 230.8 146.4 233.1 199.7 161.6 186.5 180.7 226.8 130.4 219.3 189.1 155.2 191.0 270.8 87.2 222.2 389.4 149.0 168.8 160.5 170.8 137.6 169.8 166.4 169.5 172.6 172.2 164.7 187.3 193.2 198.7 194.2 41.8 198.3 216.2 219.7 149.0 235.6 134.0 218.2 161.5 572.0 160.2 181.1 128.8 58.4 172.4 155.2 160.8 226.9 198.2 405.5 130.4 178.8 191.3 219.9 232.8 70.8 202.9 208.2 181.7 143.2 174.3 219.1 234.7 156.4 189.1 156.8 99.3 73.7 220.3 120.1 277.9 202.0 639.7 161.8 216.8 220.5 55.3 241.8 195.5 117.4 54.3 86.5 213.8 150.6 225.7 283.6 269.0 240.1 235.5 143.2 121.3 164.3 232.4 274.2 263.3 189.8 247.2 234.0 272.9 193.3 208.2 210.5 283.8 CSF1 "M-CSF, MCSF, MGC31930" ENSG00000184371 "Colony stimulating factor 1" P09603 1 109910242-109930992 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Cytokine, Growth factor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Fibroblasts: 58.9;granulocytes: 113.5;Hepatic stellate cells: 53.2;Sertoli cells: 59.2;Skeletal myocytes: 94.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "basophil: 13.2;eosinophil: 22.3" "Lineage enriched" "Detected in many" 16 "granulocytes: 22.3" "Cell line enhanced" "Detected in many" "ASC diff: 220.0;BJ hTERT+: 149.5;GAMG: 142.1;HHSteC: 338.7;HSkMC: 216.4;hTERT-RPE1: 153.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076624 Supported "Nuclear bodies,Plasma membrane" "Secreted to blood" NA NA 270000 22000000 "Cluster 52: Eosinophils - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Nuclear bodies" "HPA076624: AB_2686810" "unprognostic (2.35e-3)" "unprognostic (2.14e-1)" "unprognostic (7.36e-2)" "unprognostic (4.19e-1)" "unprognostic (3.60e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (4.25e-5)" "unprognostic (1.04e-1)" "unprognostic (1.75e-2)" "unprognostic (2.18e-1)" "unprognostic (1.72e-1)" "unprognostic (5.10e-2)" "prognostic unfavorable (1.00e-11)" "unprognostic (2.03e-1)" "unprognostic (1.88e-2)" "unprognostic (4.01e-1)" "unprognostic (3.16e-2)" 67.4 37.5 27.5 24.5 32.9 18.4 46.4 36.9 25.8 25.0 32.9 26.8 13.3 21.1 5.2 15.6 28.5 31.9 29.0 24.5 30.9 17.3 16.4 47.6 28.2 42.3 32.6 22.1 17.5 10.5 8.7 41.2 36.1 21.4 16.2 1.5 18.9 16.6 11.4 19.4 26.7 17.6 36.0 48.0 22.0 3.7 32.2 13.5 22.2 11.3 12.2 42.0 29.6 46.5 9.3 29.3 14.7 5.7 220.0 138.3 5.7 36.0 149.5 25.9 23.9 1.3 4.5 0.2 47.0 80.1 142.1 6.8 5.7 11.0 9.4 99.5 5.3 10.9 17.3 10.3 338.7 0.0 13.7 216.4 3.2 57.5 33.0 153.1 5.4 2.8 2.9 5.5 31.2 0.5 0.3 1.8 5.3 2.4 3.1 1.0 8.4 0.9 10.9 7.9 0.5 1.6 9.7 2.6 12.6 16.7 2.3 1.0 19.2 27.8 10.5 123.7 22.1 2.8 1.1 0.3 70.7 0.1 106.6 13.2 0.0 22.3 0.3 0.0 0.6 0.0 0.9 0.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.3 0.2 27.5 32.9 36.9 25.8 24.5 30.9 42.3 32.6 36.1 36.0 32.2 46.5 30.6 9.6 35.5 11.8 2.3 7.4 5.1 7.9 13.1 0.3 10.0 9.3 3.2 14.3 5.3 3.7 0.0 0.8 2.0 0.6 0.0 40.4 0.4 20.6 9.3 21.6 7.8 11.1 0.3 2.3 0.5 58.9 4.6 24.8 113.5 0.3 53.2 3.0 9.2 0.0 1.0 0.8 0.0 3.5 13.1 0.3 25.1 8.2 10.6 28.1 1.6 1.8 0.0 3.0 17.5 9.3 1.6 8.6 1.9 8.0 1.2 0.9 1.1 0.2 59.2 94.4 37.1 0.6 0.7 5.6 5.5 0.8 20.9 0.7 1.0 2.6 CSF1R "C-FMS, CD115, CSFR, FMS" ENSG00000182578 "Colony stimulating factor 1 receptor" P07333 5 150053291-150113372 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Immunity, Inflammatory response, Innate immunity" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 113.3;placenta: 103.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 103.2;Hofbauer cells: 340.4;Kupffer cells: 291.2;Langerhans cells: 73.4;Macrophages: 196.3;Microglial cells: 134.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "intermediate monocyte: 444.6;non-classical monocyte: 646.9" "Lineage enriched" "Detected in many" 5 "monocytes: 646.9" "Group enriched" "Detected in some" 4 "BEWO: 123.0;SK-BR-3: 47.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008970, HPA012323" Uncertain Supported "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 1600000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Vesicles, Plasma membrane" "CAB008970: , HPA012323: AB_1848977" "unprognostic (3.82e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-3)" "unprognostic (9.83e-2)" "unprognostic (1.20e-1)" "unprognostic (7.33e-2)" "unprognostic (1.03e-1)" "unprognostic (1.45e-1)" "unprognostic (9.37e-2)" "unprognostic (1.11e-2)" "unprognostic (2.49e-1)" "unprognostic (1.65e-1)" "prognostic unfavorable (1.08e-4)" "unprognostic (3.67e-2)" "prognostic unfavorable (4.92e-4)" "unprognostic (1.72e-2)" "unprognostic (4.61e-2)" 51.3 31.0 19.6 75.1 17.1 5.6 19.3 20.2 21.4 21.6 19.3 21.9 24.3 12.1 5.8 21.0 17.2 40.6 16.6 19.8 33.8 7.1 27.5 36.6 54.4 41.4 35.5 12.7 9.9 11.8 5.7 103.3 40.1 9.1 21.5 1.5 10.1 20.8 3.2 13.4 37.3 41.9 36.6 113.3 21.0 7.0 40.6 14.3 6.0 11.8 21.7 42.6 3.8 67.6 4.5 0.2 0.0 0.0 1.9 0.4 123.0 0.2 0.2 0.0 0.0 3.8 0.0 5.9 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.1 0.1 0.2 1.1 3.0 0.0 6.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 6.1 0.1 0.0 0.0 0.0 1.9 0.6 0.0 0.0 0.2 0.2 0.0 47.8 0.0 1.9 0.0 20.7 0.0 0.8 0.2 0.1 3.3 0.0 0.3 0.1 6.6 2.6 0.0 3.0 138.4 4.0 0.6 444.6 0.6 0.3 0.2 0.4 139.0 0.2 0.3 0.2 21.6 0.2 646.9 11.1 0.5 132.7 19.6 17.1 20.2 21.4 19.8 33.8 41.4 35.5 40.1 36.6 40.6 67.6 2.0 0.0 3.8 0.0 4.3 2.8 0.0 0.0 1.2 0.0 0.5 2.3 3.1 4.3 0.0 0.0 0.0 6.2 2.8 0.0 0.0 0.0 4.8 0.0 0.1 10.5 0.0 2.5 0.4 0.0 103.2 2.2 1.5 0.2 2.5 8.3 2.9 1.5 340.4 0.0 0.5 0.3 0.0 291.2 73.4 5.4 1.8 196.3 3.6 134.9 39.4 0.0 1.0 1.5 0.3 0.1 1.7 0.0 1.0 0.0 0.0 0.1 0.7 0.5 13.1 1.2 2.0 2.2 0.2 0.4 1.3 26.4 1.3 2.2 0.2 0.0 CSPG4 "CSPG4A, HMW-MAA, MCSP, MCSPG, MEL-CSPG, MSK16, NG2" ENSG00000173546 "Chondroitin sulfate proteoglycan 4" Q6UVK1 15 75674322-75712848 "Predicted membrane proteins" "Angiogenesis, Differentiation, Tissue remodeling" "Developmental protein, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 55.4" "Group enriched" "Detected in some" 5 "Oligodendrocyte precursor cells: 57.3;Sertoli cells: 118.3;Smooth muscle cells: 47.1" "Cancer enhanced" "Detected in all" "melanoma: 74.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 64.7;SK-MEL-30: 146.1;U-138 MG: 92.1;WM-115: 138.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA001933, HPA002951, CAB016189, HPA042785, HPA050008" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA 48000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoplasm "CAB016189: AB_784821, HPA001933: , HPA002951: AB_1854449, HPA042785: AB_10964270, HPA050008: AB_2680991" "unprognostic (5.21e-2)" "unprognostic (2.17e-3)" "unprognostic (3.55e-2)" "unprognostic (1.01e-2)" "unprognostic (3.56e-2)" "unprognostic (3.58e-1)" "unprognostic (1.09e-2)" "unprognostic (2.11e-2)" "unprognostic (1.07e-1)" "unprognostic (5.00e-2)" "unprognostic (1.63e-1)" "unprognostic (3.14e-1)" "prognostic unfavorable (7.60e-6)" "unprognostic (1.23e-2)" "unprognostic (2.04e-2)" "unprognostic (3.21e-2)" "prognostic unfavorable (4.93e-5)" 29.6 1.8 9.0 7.3 7.1 0.0 18.5 6.6 9.3 16.0 1.8 55.4 2.8 34.5 1.4 8.3 15.0 5.6 14.6 7.5 8.2 4.9 0.9 19.4 0.4 11.7 7.8 8.9 2.1 1.2 2.2 15.5 9.7 14.4 2.2 0.1 4.7 11.2 39.6 7.8 15.3 22.7 6.7 5.6 19.1 1.3 7.7 0.6 5.6 10.0 0.3 30.3 12.6 9.8 11.9 0.1 1.0 7.1 1.6 9.8 0.1 64.7 28.6 44.4 28.8 0.1 45.0 0.0 1.5 45.4 6.2 0.6 0.1 0.3 13.6 0.6 0.2 0.0 19.2 0.0 10.0 0.0 0.1 4.8 0.1 13.5 1.5 16.5 0.0 0.0 0.1 0.1 7.6 0.1 0.0 0.2 1.2 0.0 0.3 0.1 4.0 0.1 0.0 0.0 0.1 0.2 1.7 0.1 146.1 1.2 0.9 1.2 0.1 92.1 17.9 3.6 0.8 0.0 0.2 0.0 20.3 0.5 138.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.0 7.1 6.6 9.3 7.5 8.2 11.7 7.8 9.7 6.7 7.7 9.8 4.9 0.0 0.0 1.0 0.0 2.8 0.7 4.7 0.0 1.4 0.1 0.8 11.4 0.0 0.8 1.8 0.0 0.2 0.5 0.1 0.0 0.0 0.6 0.7 0.7 2.7 0.0 0.0 0.4 0.0 0.6 5.9 1.5 0.4 0.0 1.8 1.1 0.2 1.1 0.0 0.2 0.0 0.0 0.0 3.2 0.0 0.3 0.3 12.4 3.7 0.0 0.0 0.0 57.3 0.1 0.0 0.0 0.4 0.0 4.3 0.0 0.1 1.0 0.2 118.3 3.1 47.1 0.0 1.3 0.1 1.8 0.3 0.3 0.1 0.0 0.4 CST6 ENSG00000175315 "Cystatin E/M" Q15828 11 66012008-66013505 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" "Protease inhibitor, Thiol protease inhibitor" "Cancer-related genes, Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 22 "skin 1: 761.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 93.0;Club cells: 115.2;Pancreatic endocrine cells: 368.1;Respiratory ciliated cells: 404.0" "Group enriched" "Detected in many" 5 "thyroid cancer: 171.0;urothelial cancer: 43.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "A-431: 130.2;CAPAN-2: 364.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB019316, HPA044963" Enhanced Approved "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 82000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "CAB019316: , HPA044963: AB_2679158" "unprognostic (3.01e-2)" "unprognostic (5.10e-2)" "unprognostic (1.14e-1)" "unprognostic (3.59e-2)" "unprognostic (5.00e-2)" "unprognostic (2.60e-1)" "unprognostic (1.65e-1)" "unprognostic (8.38e-2)" "unprognostic (5.02e-1)" "unprognostic (8.89e-3)" "unprognostic (1.29e-3)" "unprognostic (1.46e-1)" "unprognostic (1.74e-3)" "unprognostic (5.89e-3)" "unprognostic (1.83e-1)" "unprognostic (1.64e-2)" "unprognostic (2.59e-2)" 3.2 0.3 0.1 0.3 0.1 0.2 28.5 0.8 0.4 7.4 0.8 0.4 0.0 0.3 0.6 34.6 14.9 0.5 2.8 0.1 0.3 2.6 0.3 18.3 0.0 0.2 0.2 0.7 0.7 2.1 1.6 8.1 0.1 0.9 0.0 0.0 7.4 4.9 2.0 761.4 0.3 0.1 0.1 0.2 0.6 1.8 0.4 2.7 21.4 0.0 2.2 1.2 22.5 0.2 130.2 0.0 0.0 0.6 0.0 0.0 37.6 1.4 0.0 0.3 0.2 1.0 364.6 0.0 1.8 5.1 0.1 4.5 0.0 32.3 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.8 0.6 0.2 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.0 0.0 1.5 0.5 0.8 0.2 0.7 0.0 0.0 35.8 0.4 0.1 0.8 0.1 0.0 0.2 2.5 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.8 0.4 0.1 0.3 0.2 0.2 0.1 0.1 0.4 0.2 0.1 93.0 6.1 0.0 0.6 1.1 1.7 41.4 0.6 0.0 5.3 7.1 1.2 0.0 115.2 58.8 0.0 33.3 0.0 0.1 0.0 57.4 0.2 7.7 0.1 0.9 0.0 0.0 0.0 21.6 24.4 2.0 0.0 0.6 21.6 0.1 0.4 0.1 41.1 0.0 0.0 0.0 24.4 1.4 10.0 0.8 0.0 5.3 5.4 0.0 1.1 1.3 0.0 0.0 0.0 368.1 1.1 0.4 9.8 1.9 0.0 0.5 404.0 0.1 0.0 0.3 16.0 5.2 17.6 1.0 27.6 64.2 0.7 0.0 0.4 6.1 CTNNA1 CAP102 ENSG00000044115 "Catenin alpha 1" P35221 5 138610967-138935034 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021089, HPA046119, HPA063535" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA 57000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cell Junctions" "CAB021089: AB_10123543, HPA046119: AB_2679547, HPA063535: AB_2685033" "unprognostic (2.25e-3)" "unprognostic (3.32e-2)" "unprognostic (2.82e-3)" "unprognostic (1.80e-1)" "unprognostic (8.40e-2)" "unprognostic (2.35e-1)" "unprognostic (1.66e-3)" "unprognostic (4.83e-2)" "unprognostic (2.28e-1)" "unprognostic (2.48e-1)" "prognostic unfavorable (8.02e-4)" "unprognostic (6.18e-2)" "prognostic favorable (7.34e-7)" "unprognostic (1.54e-1)" "unprognostic (2.31e-1)" "unprognostic (7.62e-2)" "unprognostic (1.04e-1)" 144.4 137.1 88.3 65.9 110.4 33.1 126.4 102.9 100.6 110.9 103.2 155.8 115.5 99.2 115.7 208.9 113.4 95.6 190.7 83.7 91.3 151.8 82.4 134.4 35.6 106.8 99.4 101.5 83.8 120.4 54.3 124.6 105.2 96.3 122.9 54.0 127.7 104.0 87.1 140.6 115.2 115.5 95.9 66.0 125.3 35.0 100.2 33.0 122.9 62.0 69.3 126.8 126.3 139.0 225.3 161.1 237.9 353.6 202.2 220.8 362.0 222.0 277.9 208.1 261.1 337.9 297.4 0.8 182.9 334.3 228.0 167.7 165.9 366.0 240.0 129.6 144.0 94.3 245.7 206.5 243.6 1.7 88.2 140.5 286.0 249.1 269.6 230.6 397.7 66.0 52.9 94.3 227.2 199.4 2.3 28.9 96.2 237.4 3.6 88.8 138.0 135.7 441.9 295.5 94.9 124.8 409.7 568.2 344.3 503.4 201.5 64.4 341.1 217.1 117.4 136.5 156.5 33.8 69.9 13.5 207.0 40.3 286.7 5.1 37.8 3.4 5.8 46.4 3.8 7.9 4.1 4.3 32.3 6.6 0.3 2.1 20.9 0.6 46.8 7.9 11.1 17.8 88.3 110.4 102.9 100.6 83.7 91.3 106.8 99.4 105.2 95.9 100.2 139.0 137.3 259.6 161.0 57.1 19.4 78.5 119.5 134.4 82.0 7.3 74.6 52.3 230.8 87.2 201.8 121.4 20.9 124.8 21.1 320.7 68.4 184.9 17.2 158.0 67.9 141.1 51.0 41.7 37.6 175.5 137.8 97.1 167.1 206.9 40.5 83.3 92.4 66.6 92.8 3.3 31.5 139.0 87.5 80.5 80.9 23.6 77.9 77.9 78.2 104.0 158.5 46.2 6.2 66.4 159.7 328.7 201.4 84.7 24.8 128.7 165.6 140.1 210.1 24.5 98.6 74.9 109.1 18.1 21.0 111.3 77.3 189.9 20.4 44.4 130.6 181.4 CUTA "ACHAP, C6orf82" ENSG00000112514 "CutA divalent cation tolerance homolog" O60888 6 33416442-33418317 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016787, HPA064369" Uncertain Approved "Plasma membrane,Focal adhesion sites" "Secreted to blood" NA NA 26000000 "Cluster 20: T-cells - T-cell receptor" "Cluster 35: Non-specific - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 32: Non-specific - Translation" "Plasma membrane, Focal adhesion sites" "CAB016787: , HPA064369: AB_2685248" "unprognostic (7.03e-2)" "unprognostic (5.44e-2)" "unprognostic (4.56e-2)" "unprognostic (8.91e-2)" "unprognostic (1.86e-1)" "unprognostic (1.03e-1)" "unprognostic (1.98e-2)" "prognostic favorable (8.50e-4)" "unprognostic (1.87e-1)" "unprognostic (2.78e-2)" "unprognostic (1.27e-3)" "unprognostic (1.91e-1)" "unprognostic (5.55e-2)" "unprognostic (9.90e-2)" "unprognostic (1.54e-1)" "unprognostic (7.94e-2)" "unprognostic (2.74e-1)" 129.0 268.0 155.3 60.3 165.9 93.9 132.4 166.2 177.1 159.6 196.0 156.7 104.5 158.7 184.8 106.4 144.4 95.1 151.1 159.6 169.9 200.3 217.8 118.3 99.0 166.1 158.3 193.8 186.3 177.2 346.6 81.5 169.6 153.8 71.2 60.3 179.2 113.0 142.8 149.5 129.1 80.1 161.9 147.1 177.5 74.2 160.9 82.7 201.6 89.2 82.5 128.2 121.9 173.0 244.5 142.0 242.7 293.8 177.6 173.9 109.7 224.0 430.1 433.1 462.7 147.5 154.1 166.1 162.2 269.1 316.0 152.4 154.5 231.3 248.9 153.2 295.1 171.8 228.9 397.0 226.3 134.2 135.9 224.7 195.8 209.8 179.8 303.7 118.8 180.9 212.9 348.7 325.1 187.2 222.0 305.1 213.8 222.6 187.5 235.9 141.8 456.4 310.1 112.3 451.7 225.4 136.2 231.3 425.8 135.5 170.8 308.7 121.3 222.6 190.0 166.5 229.8 341.7 363.9 189.5 202.9 304.9 189.3 207.8 179.2 103.6 225.8 138.1 335.1 315.7 360.7 274.6 163.6 266.5 366.5 279.2 25.6 306.9 97.2 120.0 421.9 400.4 155.3 165.9 166.2 177.1 159.6 169.9 166.1 158.3 169.6 161.9 160.9 173.0 109.5 131.4 119.3 14.0 209.5 230.6 287.9 424.5 266.9 92.6 401.0 488.6 138.2 237.4 239.7 316.3 68.8 361.6 186.2 154.0 283.7 188.3 85.4 181.8 177.9 114.7 292.1 111.7 13.0 141.0 235.5 181.4 105.5 156.8 169.9 122.6 134.2 340.1 328.6 77.4 17.4 320.1 360.1 167.1 197.1 345.2 200.0 139.2 316.6 10.3 140.0 179.7 216.3 14.1 31.2 113.3 223.9 191.5 375.7 243.3 306.6 559.1 229.5 85.9 92.1 131.1 226.7 111.0 106.4 203.5 230.4 242.9 242.4 217.8 341.3 268.4 CWH43 "CWH43-C, FLJ21511, PGAP2IP" ENSG00000109182 "Cell wall biogenesis 43 C-terminal homolog" Q9H720 4 48986275-49062081 "Predicted membrane proteins" "GPI-anchor biosynthesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 21.0;prostate: 42.8;skin 1: 25.5" "Cell type enhanced" "Detected in some" "Distal enterocytes: 10.4;Endometrial ciliated cells: 41.3;Gastric mucus-secreting cells: 10.7;Glandular and luminal cells: 21.1;Paneth cells: 15.4;Respiratory ciliated cells: 29.5;Undifferentiated cells: 15.0" "Cancer enriched" "Detected in many" 4 "prostate cancer: 20.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" "HPA042814, HPA048140" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Golgi apparatus, Plasma membrane" "HPA042814: AB_2678182, HPA048140: AB_2680280" "unprognostic (9.38e-3)" "unprognostic (6.23e-2)" "unprognostic (3.14e-2)" "prognostic favorable (1.32e-4)" "unprognostic (2.14e-1)" "unprognostic (5.00e-2)" "unprognostic (1.94e-1)" "unprognostic (2.49e-1)" "unprognostic (1.63e-1)" "unprognostic (2.07e-1)" "unprognostic (2.49e-4)" "unprognostic (1.24e-1)" "prognostic favorable (2.29e-11)" "unprognostic (5.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.82e-2)" "unprognostic (2.51e-2)" 0.0 0.0 0.0 1.4 0.0 0.0 2.0 0.0 0.0 6.0 0.0 16.9 0.4 0.6 0.4 21.0 14.5 0.0 0.0 0.0 0.0 9.0 0.7 0.7 0.0 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 42.8 15.6 0.0 3.0 7.7 0.0 25.5 0.0 0.8 0.1 0.0 9.6 0.0 0.1 0.1 10.2 0.0 1.5 2.1 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.5 0.0 0.2 1.9 0.1 0.8 0.0 0.0 0.6 0.1 0.6 0.0 2.3 7.3 0.0 0.0 0.0 10.4 1.9 0.0 0.2 41.3 2.4 0.1 0.0 0.0 0.1 0.0 0.0 0.2 10.7 21.1 0.0 0.0 0.0 0.4 0.0 0.0 0.2 4.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.6 15.4 0.0 0.0 7.6 0.0 2.9 29.5 0.0 0.0 0.0 0.5 0.0 0.5 3.2 9.1 0.0 0.2 0.0 15.0 0.3 CXADR CAR ENSG00000154639 "CXADR Ig-like cell adhesion molecule" P78310 21 17513043-17593579 "Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 323.4;Proximal enterocytes: 263.0;Suprabasal keratinocytes: 343.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.0" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 93.4;Hep G2: 63.0;NTERA-2: 109.1;RT4: 104.4" "Low region specificity" "Detected in all" "HPA003342, CAB005103, HPA030411, HPA030412" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted - unknown location" NA NA 18000 "Cluster 17: Basophils - Unknown function" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 5: NTERA-2 - Transcription" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB005103: AB_2087557, HPA003342: AB_1078588, HPA030411: AB_10599620, HPA030412: AB_10601992" "unprognostic (3.75e-1)" "unprognostic (1.03e-1)" "unprognostic (6.45e-3)" "unprognostic (2.10e-1)" "unprognostic (1.56e-1)" "prognostic favorable (3.50e-4)" "unprognostic (1.32e-1)" "unprognostic (2.52e-1)" "unprognostic (1.94e-1)" "unprognostic (2.15e-1)" "unprognostic (3.48e-3)" "unprognostic (1.04e-1)" "unprognostic (9.35e-2)" "unprognostic (3.89e-3)" "unprognostic (2.20e-1)" "unprognostic (8.27e-2)" "unprognostic (5.71e-3)" 3.6 2.9 7.0 2.8 8.7 2.6 9.8 6.6 10.8 7.7 22.8 22.5 42.3 5.3 15.2 14.5 10.6 18.3 9.3 8.9 7.1 8.3 49.3 13.6 0.7 10.4 6.8 0.4 15.8 6.8 4.7 0.3 9.3 15.1 25.6 4.9 15.4 14.2 0.4 53.4 42.6 3.3 9.7 2.4 30.9 12.5 7.3 1.5 22.1 0.0 4.1 25.6 10.9 17.7 16.8 9.0 44.6 0.1 0.0 0.0 26.7 0.2 0.2 0.7 2.7 93.4 14.6 6.2 19.7 0.0 13.3 28.1 22.8 6.2 1.0 9.3 19.0 0.1 24.1 63.0 2.9 1.8 0.1 0.0 24.6 1.3 0.4 10.8 9.0 5.5 0.3 0.4 0.0 1.1 3.7 0.1 109.1 15.2 0.0 0.1 15.2 12.5 38.7 104.4 18.5 12.3 10.9 12.6 6.7 45.8 25.4 0.3 0.5 0.2 25.8 0.4 6.6 4.5 7.7 0.4 3.6 0.1 0.6 1.0 0.1 0.1 0.1 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.6 0.2 0.3 0.2 0.0 0.0 0.1 0.2 7.0 8.7 6.6 10.8 8.9 7.1 10.4 6.8 9.3 9.7 7.3 17.7 0.2 141.1 79.0 2.6 1.0 323.4 172.7 110.6 132.6 16.9 58.6 28.2 29.8 161.5 106.6 103.0 27.1 0.8 0.3 238.4 5.9 130.0 5.3 118.9 8.3 4.8 80.8 9.9 60.4 93.7 0.2 8.6 94.3 128.9 5.7 1.1 47.8 127.7 0.6 0.0 43.0 107.5 81.4 22.9 13.1 7.7 2.1 3.3 23.2 40.3 0.7 13.4 0.0 78.9 161.4 93.4 155.3 0.0 1.6 125.1 263.0 4.0 85.6 11.2 6.6 0.2 5.3 6.4 24.5 117.0 343.8 0.7 4.3 0.5 107.0 202.7 CYB5D2 MGC32124 ENSG00000167740 "Cytochrome b5 domain containing 2" Q8WUJ1 17 4143168-4187310 "Predicted intracellular proteins, Predicted secreted proteins" Neurogenesis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Spermatocytes: 130.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 74.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011032, HPA042299" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 68: Epididymis - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Endoplasmic reticulum, Plasma membrane" "HPA011032: , HPA042299: AB_10793879" "unprognostic (2.57e-2)" "unprognostic (2.89e-2)" "unprognostic (4.16e-2)" "prognostic favorable (6.19e-4)" "unprognostic (1.88e-2)" "unprognostic (1.75e-2)" "prognostic favorable (4.98e-6)" "unprognostic (1.57e-1)" "unprognostic (2.47e-1)" "unprognostic (9.71e-3)" "prognostic favorable (7.76e-5)" "unprognostic (2.04e-1)" "prognostic favorable (2.03e-10)" "unprognostic (2.01e-3)" "unprognostic (8.73e-2)" "unprognostic (1.82e-1)" "unprognostic (2.97e-1)" 19.0 21.7 17.4 6.1 17.3 4.3 18.2 17.4 20.1 15.9 14.2 10.7 15.2 15.6 28.5 10.9 18.7 16.3 14.0 16.7 19.6 25.5 29.0 9.7 9.3 18.1 17.6 20.8 19.7 30.9 24.1 10.8 17.8 13.5 7.4 9.2 20.0 17.6 16.2 14.4 12.1 8.4 17.6 9.6 16.0 29.3 17.9 10.2 22.7 14.9 7.2 12.9 11.7 18.7 16.2 21.6 11.8 12.7 74.7 22.5 5.2 15.7 31.5 11.0 10.9 6.3 10.3 5.3 13.6 17.4 9.2 22.5 4.9 7.1 4.4 17.9 25.7 5.0 13.5 10.5 13.7 2.1 9.5 28.8 17.0 6.2 11.7 22.3 20.1 11.5 5.1 31.2 8.3 20.6 7.8 3.4 4.3 13.7 11.5 9.2 10.6 12.5 25.1 8.5 9.3 8.1 17.2 9.9 23.5 13.1 25.6 3.2 28.5 15.7 4.0 14.5 8.0 5.8 4.9 3.9 19.9 4.5 6.2 0.6 10.8 13.6 5.9 9.2 6.7 8.1 9.3 7.4 10.5 7.1 8.6 8.0 9.5 5.5 8.7 11.3 11.2 8.2 17.4 17.3 17.4 20.1 16.7 19.6 18.1 17.6 17.8 17.6 17.9 18.7 57.4 12.8 10.3 9.1 17.2 53.7 18.4 36.0 12.5 26.9 35.4 36.7 9.8 45.8 21.8 31.3 58.4 55.7 11.4 18.5 52.8 34.3 28.5 36.6 20.0 34.4 13.8 33.3 7.6 27.0 29.1 23.8 19.4 23.4 11.4 22.3 41.0 32.9 21.4 40.4 10.4 16.0 36.7 24.0 23.8 30.6 28.9 17.3 14.2 4.7 15.4 37.6 15.5 8.5 10.0 26.9 18.9 28.6 17.6 8.3 39.7 55.7 38.5 30.4 0.0 15.2 20.1 130.3 29.2 9.5 42.9 38.6 15.8 39.3 16.6 15.8 CYBC1 "C17orf62, Eros, FLJ90469, MGC4368" ENSG00000178927 "Cytochrome b-245 chaperone 1" Q9BQA9 17 82442586-82450829 "Predicted intracellular proteins, Predicted membrane proteins" "Immunity, Innate immunity" Chaperone "Chronic granulomatous disease, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 47.4;Ductal cells: 39.7;Granulosa cells: 56.1;Hofbauer cells: 80.2;monocytes: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045696 Uncertain Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cell Junctions" "HPA045696: AB_2679421" "unprognostic (1.87e-2)" "unprognostic (6.92e-3)" "unprognostic (2.25e-1)" "unprognostic (2.15e-3)" "unprognostic (5.75e-2)" "unprognostic (2.05e-3)" "unprognostic (3.81e-3)" "unprognostic (4.86e-2)" "unprognostic (1.66e-1)" "unprognostic (1.44e-1)" "unprognostic (3.49e-3)" "unprognostic (7.99e-2)" "prognostic unfavorable (6.83e-11)" "unprognostic (1.47e-1)" "unprognostic (5.51e-2)" "unprognostic (7.78e-2)" "unprognostic (9.14e-3)" 39.2 35.7 34.4 70.1 36.1 37.2 37.4 36.7 42.6 40.9 36.3 33.8 24.6 33.7 23.7 34.1 34.9 46.0 30.7 33.2 35.6 51.2 64.9 41.4 110.5 41.8 37.8 33.8 45.0 24.5 25.9 30.7 37.7 43.4 27.7 9.9 30.8 23.2 14.9 29.4 49.3 40.7 37.1 117.4 36.9 17.8 36.7 63.3 28.9 13.6 72.1 49.7 28.2 40.6 48.5 67.4 37.1 61.4 57.9 60.6 35.0 42.2 51.6 61.8 73.1 26.2 47.8 122.4 37.8 60.6 75.4 48.3 25.7 32.4 42.6 87.4 21.1 33.4 19.2 30.6 59.3 38.1 94.4 68.5 45.7 53.1 29.3 59.0 81.5 90.3 28.4 88.2 52.9 50.8 160.2 33.0 27.5 65.0 35.3 120.1 22.7 93.1 44.8 60.7 31.7 60.7 77.0 88.1 55.7 66.3 91.4 148.3 27.9 46.7 46.0 79.3 45.9 157.8 58.3 93.1 61.2 61.0 42.5 223.8 136.7 182.9 96.3 181.3 74.7 114.8 88.2 93.6 125.2 115.9 73.0 71.1 300.6 104.5 169.4 130.9 101.1 161.4 34.4 36.1 36.7 42.6 33.2 35.6 41.8 37.8 37.7 37.1 36.7 40.6 35.6 0.0 0.0 0.0 21.4 0.0 0.0 0.0 0.0 0.0 19.0 17.1 0.0 0.0 0.0 22.0 0.0 27.6 47.4 0.0 9.8 39.7 0.0 11.9 21.9 12.9 0.0 0.0 0.0 33.6 36.1 10.9 0.0 12.4 0.0 56.1 0.0 0.0 80.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.5 0.0 0.0 54.8 0.0 0.0 0.0 0.0 34.9 0.0 0.0 11.1 0.0 0.0 19.6 0.0 0.0 0.0 0.0 12.3 0.0 0.0 0.0 0.0 27.6 19.5 23.8 0.0 0.0 CYP2C18 "CPCI, CYP2C, CYP2C17, P450IIC17" ENSG00000108242 "Cytochrome P450 family 2 subfamily C member 18" P33260 10 94683729-94736190 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 102.8;liver: 197.0;stomach 1: 67.2" "Cell type enhanced" "Detected in some" "Gastric mucus-secreting cells: 68.8;Hepatocytes: 124.0;Proximal enterocytes: 62.5;Squamous epithelial cells: 22.8" "Cancer enhanced" "Detected in many" "liver cancer: 18.9" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.2;OE19: 1.9" "Not detected" "Not detected" HPA074424 Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA074424: " "unprognostic (2.40e-1)" "unprognostic (1.75e-2)" "unprognostic (2.69e-1)" "unprognostic (1.10e-2)" "unprognostic (1.32e-2)" "unprognostic (2.57e-1)" "unprognostic (2.71e-1)" "unprognostic (9.78e-2)" "unprognostic (2.28e-1)" "unprognostic (4.22e-3)" "unprognostic (1.62e-3)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (6.81e-3)" 0.3 0.0 0.0 1.6 0.1 0.0 0.3 0.2 0.1 5.3 0.0 5.9 102.8 0.1 0.0 30.9 0.0 16.3 0.0 0.1 0.0 0.3 197.0 0.8 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 2.5 0.0 5.4 0.0 0.0 4.4 83.1 0.1 0.1 0.0 67.2 0.1 0.1 0.3 0.0 0.0 7.1 0.2 9.5 0.2 0.0 0.1 0.0 0.1 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.9 0.0 0.0 0.0 0.4 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.1 0.2 0.0 0.0 3.3 0.0 0.3 0.1 0.0 1.6 0.0 0.0 0.0 0.1 0.1 17.2 3.2 0.0 0.0 0.1 0.0 6.7 0.0 1.5 0.0 0.6 0.1 0.0 0.0 2.7 0.5 6.9 0.2 0.1 68.8 1.3 0.0 0.0 1.8 124.0 0.0 0.0 0.8 2.1 2.0 2.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 9.1 3.9 0.0 0.3 0.0 62.5 0.0 0.9 0.0 0.0 0.0 0.1 0.1 0.3 22.8 1.7 1.5 0.1 0.1 5.7 0.0 CYP2C8 CPC8 ENSG00000138115 "Cytochrome P450 family 2 subfamily C member 8" P10632 10 95036772-95069497 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 359 "liver: 2156.6" "Cell type enriched" "Detected in some" 12 "Hepatocytes: 1834.2" "Cancer enriched" "Detected in some" 82 "liver cancer: 102.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA013547, HPA013970, HPA015066, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 62: Liver - Hemostasis" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "HPA013547: AB_1847435, HPA013970: AB_1847434, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.33e-2)" "unprognostic (1.38e-1)" "unprognostic (1.53e-1)" "unprognostic (1.55e-1)" "unprognostic (4.41e-2)" "unprognostic (1.09e-2)" "unprognostic (1.80e-3)" "unprognostic (4.29e-2)" "unprognostic (1.03e-1)" "unprognostic (3.38e-1)" "prognostic favorable (9.82e-4)" "unprognostic (2.85e-1)" "unprognostic (1.44e-3)" "unprognostic (2.63e-1)" "unprognostic (7.88e-2)" "unprognostic (1.39e-1)" "unprognostic (4.05e-4)" 0.3 1.8 1.7 0.0 1.9 0.2 0.3 1.4 2.1 0.3 1.4 0.4 0.2 0.1 0.3 0.1 1.1 4.6 0.3 1.8 2.2 1.4 2156.6 0.4 0.1 1.7 2.2 0.1 1.7 0.5 3.1 0.1 1.8 0.6 0.0 3.1 0.2 0.3 0.2 0.1 1.1 0.0 1.4 1.0 6.0 4.0 2.1 0.2 0.9 0.0 0.1 0.2 0.2 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.5 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 1.9 1.4 2.1 1.8 2.2 1.7 2.2 1.8 1.4 2.1 1.8 0.0 0.0 0.0 1.6 8.9 0.0 0.1 0.0 0.0 1.1 0.1 0.0 0.2 147.3 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 7.3 0.9 0.1 2.0 1.8 57.5 4.5 0.2 0.0 0.1 0.0 0.2 0.0 0.6 52.8 1834.2 0.0 5.0 3.7 0.1 0.0 70.9 0.0 7.4 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 1.2 0.5 1.2 0.0 0.0 0.1 1.0 0.8 0.9 1.7 0.0 0.0 0.3 2.1 0.6 0.0 0.0 0.0 3.3 0.0 0.2 0.2 CYP2C9 "CYP2C10, P450IIC9" ENSG00000138109 "Cytochrome P450 family 2 subfamily C member 9" P11712 10 94938658-94990091 "Enzymes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Lipid metabolism, Steroid metabolism, Sterol metabolism" "Monooxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 20 "liver: 1719.9" "Cell type enriched" "Detected in some" 26 "Hepatocytes: 1704.9" "Cancer enriched" "Detected in some" 41 "liver cancer: 118.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015066, CAB016123, HPA074424" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 2: Hepatocytes - Metabolism" Vesicles "Plasma membrane" "CAB016123: AB_629363, HPA015066: AB_1847433, HPA074424: " "unprognostic (3.37e-1)" "unprognostic (5.68e-2)" "unprognostic (9.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.83e-2)" "prognostic favorable (2.83e-6)" "unprognostic (2.37e-1)" "unprognostic (2.05e-2)" "unprognostic (4.93e-2)" "unprognostic (1.26e-4)" "unprognostic (7.55e-2)" "unprognostic (1.12e-1)" "unprognostic (2.45e-2)" "unprognostic (1.24e-2)" 0.2 0.0 0.0 0.4 0.0 0.2 0.1 0.1 0.0 1.2 0.0 2.7 87.8 0.0 0.0 7.7 0.0 7.9 0.0 0.0 0.0 4.3 1719.9 0.2 0.1 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.3 0.0 1.0 0.0 0.0 2.3 46.2 0.1 0.0 0.5 18.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 2.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 18.6 0.2 1.8 0.0 0.0 0.0 1.5 0.0 7.6 0.0 0.8 0.7 1.1 0.0 16.0 0.0 0.7 0.0 0.2 44.4 7.4 0.0 0.0 26.7 1704.9 0.0 0.0 0.1 1.4 0.0 34.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.0 2.6 0.0 0.1 0.0 65.3 1.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.5 0.0 0.1 1.9 0.0 2.7 0.0 DAAM1 KIAA0666 ENSG00000100592 "Dishevelled associated activator of morphogenesis 1" Q9Y4D1 14 59188646-59371405 "Plasma proteins, Predicted intracellular proteins" "Wnt signaling pathway" Actin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 467.3;Suprabasal keratinocytes: 332.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HaCaT: 39.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026605, HPA064789" Uncertain Approved "Plasma membrane,Cytosol" NA NA 9700 "Cluster 6: Non-specific - Transcription" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Plasma membrane, Cytosol" "HPA026605: AB_1847464, HPA064789: AB_2685352" "unprognostic (2.81e-1)" "unprognostic (9.70e-2)" "unprognostic (3.85e-2)" "unprognostic (2.74e-1)" "unprognostic (2.32e-1)" "unprognostic (1.84e-1)" "unprognostic (1.76e-2)" "unprognostic (2.48e-1)" "unprognostic (2.02e-1)" "unprognostic (6.40e-2)" "unprognostic (1.98e-1)" "unprognostic (4.64e-2)" "prognostic favorable (3.77e-4)" "unprognostic (5.01e-2)" "unprognostic (3.29e-1)" "unprognostic (1.39e-1)" "unprognostic (3.15e-2)" 14.5 6.2 13.0 6.8 13.6 5.4 10.4 12.6 12.8 13.6 22.8 13.5 4.8 13.5 5.6 19.0 7.7 5.9 19.3 11.8 14.8 6.9 12.6 10.5 11.1 7.9 8.1 8.0 9.3 20.6 5.3 9.1 8.3 11.9 8.5 24.9 9.4 11.0 5.6 30.9 7.2 10.9 7.8 13.1 7.0 6.9 11.2 4.8 7.4 4.7 15.6 9.5 15.1 10.7 18.2 1.9 13.1 3.5 7.8 5.8 17.1 2.5 2.3 4.7 4.8 9.4 16.6 20.4 4.4 5.6 9.6 39.7 11.8 10.0 4.0 9.0 4.1 6.8 4.8 11.8 4.8 7.9 3.8 3.9 10.6 3.9 4.7 10.8 11.3 10.2 11.9 9.9 2.8 17.0 6.9 4.9 7.5 12.9 5.6 6.3 11.1 2.0 6.8 13.5 20.3 4.8 15.8 23.1 16.1 8.7 30.5 2.1 10.8 3.9 7.4 8.4 2.2 2.2 2.7 22.1 5.0 1.5 8.7 7.7 2.0 2.6 2.3 2.4 3.0 10.8 3.0 2.3 2.2 4.6 2.4 2.6 2.8 6.7 3.5 18.3 4.0 1.9 13.0 13.6 12.6 12.8 11.8 14.8 7.9 8.1 8.3 7.8 11.2 10.7 62.2 35.3 27.0 160.6 37.8 467.3 172.4 128.6 30.7 110.7 56.8 40.6 149.3 38.6 82.3 29.5 308.6 33.0 66.9 47.0 23.5 63.8 40.0 68.4 142.9 71.9 87.7 140.0 143.7 93.1 27.6 67.3 21.9 54.6 26.0 155.2 102.4 47.2 32.8 195.2 202.0 56.7 73.2 16.3 55.8 16.6 60.3 36.1 90.7 66.5 25.2 96.5 16.5 74.9 24.3 191.4 45.1 74.1 30.8 104.2 24.7 12.8 102.4 168.7 32.9 84.6 66.3 51.3 46.3 52.8 332.0 34.2 25.1 25.1 38.1 84.2 DAGLB "DAGLBETA, KCCR13L" ENSG00000164535 "Diacylglycerol lipase beta" Q8NCG7 7 6409126-6484190 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA069377 Supported "Nucleoplasm,Plasma membrane" No No "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA069377: AB_2686132" "unprognostic (2.39e-1)" "unprognostic (4.61e-2)" "unprognostic (2.13e-3)" "unprognostic (1.42e-1)" "unprognostic (9.04e-3)" "unprognostic (3.68e-2)" "unprognostic (1.78e-3)" "unprognostic (2.36e-1)" "unprognostic (2.22e-1)" "prognostic unfavorable (7.18e-5)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (1.54e-4)" "unprognostic (2.18e-1)" "unprognostic (1.14e-1)" "unprognostic (1.93e-1)" "unprognostic (1.81e-2)" 7.3 15.6 9.9 6.7 9.9 15.0 6.6 7.3 11.1 7.0 5.9 6.7 7.6 5.8 3.6 8.0 5.9 6.4 5.6 11.2 8.8 4.9 7.9 9.3 7.4 9.7 7.7 7.9 6.9 7.0 4.3 8.7 8.0 5.3 5.0 3.4 7.7 4.5 13.3 12.4 7.6 5.8 8.4 8.5 7.1 5.5 8.1 8.1 7.5 7.0 6.7 5.8 7.3 10.7 21.6 23.9 10.9 14.3 16.1 12.5 8.4 29.8 21.3 26.6 28.7 13.6 24.4 12.3 12.5 15.4 64.8 32.4 17.8 16.7 15.2 5.8 11.7 6.6 26.9 9.4 17.3 18.8 10.1 11.3 27.2 17.9 17.5 10.7 11.7 15.6 18.2 6.1 15.9 16.2 6.7 26.9 39.6 11.3 18.5 57.4 12.7 25.5 16.8 8.1 13.5 8.4 17.7 26.7 5.3 17.2 19.0 34.7 14.4 22.4 41.9 28.1 13.9 6.2 11.2 10.4 11.3 28.9 28.2 10.8 22.8 22.0 6.2 21.3 5.5 8.2 4.8 4.1 28.6 4.7 11.4 6.7 10.2 3.9 19.5 5.0 4.3 12.2 9.9 9.9 7.3 11.1 11.2 8.8 9.7 7.7 8.0 8.4 8.1 10.7 6.5 9.6 12.6 5.9 7.9 16.8 3.6 6.2 12.0 4.5 5.7 5.7 3.1 4.3 5.0 5.5 2.1 5.1 4.8 12.2 0.0 7.0 0.4 10.3 6.8 9.0 2.4 13.3 13.8 6.2 8.9 5.4 19.4 19.9 3.8 5.5 8.9 8.0 17.2 0.0 9.2 5.8 6.1 16.1 17.4 1.7 6.2 16.3 5.4 26.2 15.8 1.4 7.2 2.5 6.5 12.2 8.0 2.2 5.0 5.7 10.6 1.6 3.8 4.3 0.0 4.0 5.0 8.5 7.1 9.4 13.4 12.4 6.7 7.4 7.6 4.3 DBN1 D0S117E ENSG00000113758 "Drebrin 1" Q16643 5 177456608-177474401 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Actin-binding, Developmental protein" "Alzheimer disease, Amyloidosis, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Ductal cells: 87.1;Pancreatic endocrine cells: 64.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 5.8;granulocytes: 9.4;T-cells: 14.0" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA051452, HPA056940" Enhanced Supported Supported "Plasma membrane,Actin filaments" NA NA 2000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA051452: AB_2681489, HPA056940: AB_2683279" "unprognostic (3.81e-2)" "unprognostic (6.60e-3)" "unprognostic (2.88e-2)" "unprognostic (7.57e-3)" "unprognostic (9.32e-2)" "unprognostic (5.68e-2)" "unprognostic (2.01e-3)" "unprognostic (4.29e-2)" "unprognostic (1.73e-2)" "unprognostic (7.92e-2)" "unprognostic (2.94e-2)" "unprognostic (3.64e-1)" "prognostic favorable (8.28e-4)" "unprognostic (1.53e-1)" "unprognostic (4.56e-2)" "unprognostic (1.05e-1)" "unprognostic (1.76e-3)" 59.4 9.3 44.8 17.6 52.5 6.4 36.5 19.3 71.7 59.7 18.6 67.6 9.5 84.4 10.2 30.9 44.7 24.4 39.7 70.1 45.4 52.0 4.0 24.7 9.0 33.8 25.4 34.8 16.9 17.1 45.8 7.1 32.3 29.7 5.9 5.5 33.1 23.9 27.6 36.6 25.0 28.6 24.0 14.2 47.4 27.0 39.7 14.6 33.4 9.0 4.4 61.0 33.1 35.5 17.4 56.1 182.0 319.1 42.4 66.2 56.5 198.6 50.3 113.4 94.5 193.9 59.0 0.3 139.5 155.1 39.0 27.0 80.9 144.0 53.6 5.2 70.4 111.6 72.9 82.0 149.3 43.0 20.5 87.1 37.1 127.3 38.0 113.3 189.4 131.4 54.0 26.0 84.2 25.1 115.1 63.8 264.1 5.7 123.4 338.1 197.2 34.5 85.3 23.7 213.7 289.8 67.0 28.8 111.5 58.4 78.7 42.6 298.6 126.7 169.3 28.2 94.9 6.3 3.1 177.5 53.2 40.5 80.5 9.4 1.4 1.1 10.3 0.8 14.0 0.3 0.3 7.2 1.8 0.4 0.4 5.2 3.2 0.3 0.8 5.8 0.2 2.2 44.8 52.5 19.3 71.7 70.1 45.4 33.8 25.4 32.3 24.0 39.7 35.5 44.2 3.2 1.5 8.1 1.2 10.3 13.7 24.6 9.1 7.0 7.6 9.1 5.1 2.8 11.1 9.2 4.2 1.0 4.5 1.4 1.9 87.1 16.9 8.4 44.0 43.2 40.7 4.8 15.7 43.4 2.8 56.1 11.7 18.4 10.8 49.4 20.7 0.0 1.7 42.1 13.0 2.4 40.7 1.8 8.9 41.6 50.1 6.1 8.8 2.8 2.4 13.4 1.0 5.0 1.0 64.5 0.6 41.0 4.0 16.9 0.6 6.3 5.2 4.5 19.7 10.8 43.4 6.5 26.7 20.1 7.2 0.8 10.4 8.1 3.9 7.5 DBNL "ABP1, HIP-55, SH3P7" ENSG00000136279 "Drebrin like" Q9UJU6 7 44044640-44069456 "Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Endocytosis, Immunity, Transport" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "monocytes: 338.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020265, HPA027735" Enhanced Supported "Vesicles,Plasma membrane" NA NA 3500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 3: Monocytes - Immune response regulation" "Vesicles, Plasma membrane" "HPA020265: AB_1850723, HPA027735: AB_10603790" "unprognostic (9.57e-2)" "unprognostic (1.11e-1)" "unprognostic (1.04e-2)" "unprognostic (5.63e-2)" "prognostic unfavorable (2.12e-5)" "unprognostic (2.25e-1)" "unprognostic (6.18e-3)" "unprognostic (1.83e-1)" "unprognostic (5.88e-2)" "unprognostic (8.92e-2)" "unprognostic (5.76e-3)" "unprognostic (5.92e-2)" "unprognostic (2.11e-1)" "unprognostic (1.79e-1)" "unprognostic (2.10e-1)" "unprognostic (1.46e-1)" "unprognostic (9.51e-2)" 58.1 51.6 44.2 62.8 45.1 76.6 51.3 41.7 50.4 72.4 39.9 54.6 34.7 56.0 20.2 189.0 47.8 47.2 49.2 45.8 45.2 50.7 51.1 57.8 99.6 46.2 44.8 38.0 44.3 38.4 47.8 34.9 48.4 57.0 30.6 9.4 57.5 38.0 34.3 59.9 64.7 44.8 44.3 119.5 54.7 20.8 44.6 64.8 47.6 16.4 89.1 60.3 92.0 43.4 57.6 89.1 60.5 56.6 77.0 49.7 46.0 95.9 93.6 111.5 91.5 90.0 82.5 132.3 70.0 126.1 133.6 101.9 35.6 130.6 40.7 70.6 38.9 51.9 73.8 52.4 78.5 75.8 70.3 46.6 53.3 107.1 35.2 71.5 74.1 83.9 63.8 49.3 105.5 91.5 136.5 85.3 43.1 72.9 73.0 69.4 48.1 64.5 69.8 90.5 65.6 89.8 69.6 121.5 24.4 43.8 94.0 99.4 121.1 82.7 75.5 49.5 113.6 102.7 49.4 81.2 78.3 83.2 183.8 263.3 377.1 295.0 190.3 422.7 148.3 253.9 138.0 155.0 362.5 261.7 136.5 145.1 357.4 192.4 437.9 376.6 183.1 558.8 44.2 45.1 41.7 50.4 45.8 45.2 46.2 44.8 48.4 44.3 44.6 43.4 49.9 44.8 36.2 10.7 105.4 17.6 34.1 62.9 19.4 33.0 26.7 24.0 30.6 25.8 42.2 31.3 35.5 78.9 101.6 58.5 45.0 87.0 10.3 30.7 39.3 44.8 37.8 45.8 7.4 73.2 146.4 39.3 54.6 50.7 65.9 42.3 32.5 22.5 176.0 40.4 6.7 50.0 38.7 129.6 48.6 10.6 37.0 113.4 55.2 7.5 338.3 42.5 112.3 5.5 11.4 105.9 74.0 33.8 50.2 31.5 49.0 33.6 21.6 38.6 6.6 29.0 54.6 24.4 12.8 64.4 26.7 87.3 69.5 51.9 44.0 51.1 DCAF16 "C4orf30, FLJ20280" ENSG00000163257 "DDB1 and CUL4 associated factor 16" Q9NXF7 4 17800655-17810758 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042487 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 24: NB-4 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042487: AB_10795505" "unprognostic (2.23e-3)" "unprognostic (1.05e-1)" "unprognostic (1.19e-1)" "unprognostic (3.97e-1)" "unprognostic (8.02e-2)" "unprognostic (2.14e-1)" "prognostic unfavorable (6.40e-4)" "prognostic favorable (5.78e-4)" "unprognostic (5.31e-2)" "unprognostic (3.30e-1)" "unprognostic (1.45e-2)" "unprognostic (3.19e-2)" "unprognostic (1.78e-1)" "unprognostic (8.72e-2)" "unprognostic (1.68e-1)" "unprognostic (2.23e-3)" "prognostic favorable (7.67e-4)" 9.6 8.2 4.5 8.0 7.0 18.1 13.0 6.4 6.7 12.8 2.9 10.4 7.9 13.8 10.2 7.9 11.9 6.6 8.4 4.2 7.4 9.2 4.8 9.1 11.9 6.1 5.8 19.4 11.3 12.3 13.3 9.8 5.7 10.6 9.5 13.3 10.9 7.9 8.2 15.0 10.2 8.9 4.5 8.9 8.8 10.9 7.8 12.0 10.1 4.4 11.4 10.0 10.2 9.4 21.7 4.6 24.3 25.5 6.8 11.9 13.2 13.9 16.3 16.2 19.1 13.1 17.2 24.2 10.8 12.9 13.1 10.7 14.4 14.7 23.9 8.3 13.2 34.2 16.0 21.5 16.3 30.4 13.4 15.5 11.8 20.6 20.3 10.8 11.3 23.6 37.4 39.3 9.4 8.2 33.4 29.0 20.0 6.3 13.1 35.0 27.8 15.7 7.1 16.9 36.0 28.9 14.8 3.9 16.9 12.2 14.3 8.1 14.5 18.7 14.7 20.8 17.8 17.3 7.4 29.4 15.4 20.6 12.8 7.8 1.4 2.1 2.5 1.6 3.3 2.0 2.7 2.8 0.9 2.9 3.4 3.2 1.0 2.1 1.1 1.8 2.1 1.3 4.5 7.0 6.4 6.7 4.2 7.4 6.1 5.8 5.7 4.5 7.8 9.4 11.6 19.2 24.8 13.1 17.6 25.4 24.3 9.4 25.6 12.2 16.3 16.9 21.9 12.8 14.4 9.2 6.2 17.6 27.0 8.6 13.7 9.9 19.6 12.9 18.4 13.0 17.5 21.7 20.2 7.7 10.0 15.9 14.3 13.3 17.1 24.8 11.4 6.4 7.7 15.2 20.2 12.5 14.2 11.9 11.3 11.5 21.1 9.4 10.6 15.0 10.2 27.5 7.2 29.1 36.7 11.8 7.6 22.2 27.6 14.6 9.2 5.1 17.1 14.6 13.1 21.7 16.2 28.8 17.3 19.5 21.2 12.3 20.3 19.0 13.9 19.2 DCHS2 "CDH27, CDHJ, CDHR7, FLJ20047, PCDH23, PCDHJ" ENSG00000197410 "Dachsous cadherin-related 2" Q6V1P9 4 154231742-154491799 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "intestine: 1.7" "Cell type enhanced" "Detected in some" "Astrocytes: 63.0;Early spermatids: 20.7;Excitatory neurons: 30.3;Horizontal cells: 25.2;Inhibitory neurons: 13.2;Late spermatids: 19.4;Microglial cells: 13.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 8 "U-2 OS: 4.7" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA064159 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA064159: AB_2685201" "unprognostic (1.38e-2)" "unprognostic (1.51e-1)" "unprognostic (5.74e-3)" "unprognostic (5.93e-2)" "unprognostic (7.43e-3)" "unprognostic (1.29e-1)" "unprognostic (2.27e-4)" "unprognostic (1.18e-1)" "unprognostic (4.00e-1)" "unprognostic (1.61e-1)" "unprognostic (2.53e-3)" "unprognostic (1.62e-1)" "unprognostic (1.06e-3)" "unprognostic (3.13e-1)" "unprognostic (2.62e-1)" "unprognostic (1.49e-1)" "unprognostic (1.68e-3)" 0.0 0.1 0.6 0.0 0.8 0.0 0.1 0.3 0.5 0.9 0.0 1.7 0.0 1.4 0.0 0.0 0.9 0.1 0.0 0.4 0.8 0.1 0.0 0.1 0.0 0.5 1.3 0.7 0.0 0.0 0.6 0.0 0.3 0.4 0.0 0.1 0.1 0.2 0.0 0.2 0.3 0.1 0.7 0.0 1.2 1.1 1.1 0.0 0.0 0.0 0.0 0.6 0.1 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 0.3 0.5 0.4 0.8 0.5 1.3 0.3 0.7 1.1 1.4 0.0 0.0 0.0 63.0 0.0 0.4 0.2 0.8 0.0 0.4 0.8 0.6 1.9 0.0 1.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.7 0.1 0.5 0.3 6.7 0.0 30.3 0.0 0.0 1.8 3.6 0.0 0.0 1.2 0.0 0.0 0.1 25.2 13.2 0.1 0.0 0.0 0.7 19.4 0.6 0.0 0.0 13.1 0.0 0.2 0.0 6.6 1.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.9 0.2 0.0 0.3 0.5 1.7 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 DCT TYRP2 ENSG00000080166 "Dopachrome tautomerase" P40126 13 94436811-94479682 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Melanin biosynthesis" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "skin 1: 107.4" "Cell type enriched" "Detected in some" 23 "Melanocytes: 3552.1" "Cancer enriched" "Detected in some" 215 "melanoma: 155.5" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 272 "SK-MEL-30: 257.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA010742, HPA010743, HPA010800, CAB017634" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 61: Skin - Cornification" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Vesicles "CAB017634: AB_1130818, HPA010742: , HPA010743: AB_1847519, HPA010800: AB_1847520" "unprognostic (5.99e-2)" "unprognostic (1.67e-2)" "unprognostic (1.54e-2)" "unprognostic (3.17e-2)" "unprognostic (2.45e-2)" "unprognostic (3.35e-2)" "unprognostic (2.15e-2)" "unprognostic (2.81e-2)" "unprognostic (6.07e-2)" "unprognostic (1.81e-1)" "unprognostic (3.64e-3)" "unprognostic (1.06e-2)" "unprognostic (6.18e-5)" "unprognostic (6.97e-2)" "unprognostic (9.87e-2)" "unprognostic (1.22e-3)" "unprognostic (2.42e-1)" 0.4 0.4 0.6 0.0 1.0 0.1 3.0 0.4 0.7 0.2 0.2 0.3 0.0 0.3 0.9 0.0 0.9 0.1 0.1 0.6 0.6 0.2 0.2 0.1 0.0 0.6 0.6 0.4 0.4 0.0 1.6 0.0 0.5 0.3 0.0 0.9 1.5 0.3 0.4 107.4 0.1 0.1 0.6 0.1 0.1 0.6 0.6 0.5 0.2 0.1 0.0 0.2 0.3 0.5 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.9 0.0 0.0 0.0 257.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.3 0.2 0.6 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.4 0.7 0.6 0.6 0.6 0.6 0.5 0.6 0.6 0.5 0.0 0.0 0.0 23.5 0.0 152.3 0.1 0.0 0.0 1.0 0.3 0.5 0.9 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.5 0.1 1.2 0.0 0.0 16.1 0.2 0.0 1.4 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.0 14.4 0.0 0.0 0.0 25.5 23.8 0.9 0.0 3552.1 1.9 0.0 3.5 0.0 6.6 2.4 0.0 0.0 0.7 0.0 0.0 0.0 0.2 0.2 0.3 0.0 0.5 1.0 0.5 0.8 0.0 33.4 0.0 0.9 0.1 0.0 0.0 DCUN1D2 "C13orf17, FLJ10704, FLJ20092" ENSG00000150401 "Defective in cullin neddylation 1 domain containing 2" Q6PH85 13 113455819-113490951 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 98.6;skeletal muscle: 108.7;tongue: 69.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 79.6;Excitatory neurons: 43.9;Inhibitory neurons: 37.9;Oligodendrocytes: 42.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 11.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 11.3" "Cell line enhanced" "Detected in all" "SCLC-21H: 54.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039349 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 38: Heart - Muscle contraction" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039349: AB_10673240" "unprognostic (3.09e-1)" "unprognostic (1.35e-1)" "unprognostic (1.78e-1)" "unprognostic (4.69e-2)" "unprognostic (7.43e-2)" "unprognostic (7.68e-2)" "unprognostic (4.33e-2)" "unprognostic (1.15e-1)" "unprognostic (1.40e-1)" "unprognostic (2.02e-2)" "prognostic favorable (5.65e-5)" "unprognostic (1.21e-2)" "unprognostic (7.20e-2)" "unprognostic (3.57e-2)" "unprognostic (1.28e-1)" "unprognostic (3.69e-2)" "unprognostic (1.25e-2)" 8.1 8.4 9.7 4.4 8.8 14.0 7.6 23.4 14.6 8.9 30.1 9.2 4.6 9.4 9.4 6.4 7.7 5.4 98.6 8.5 9.7 8.3 8.5 7.7 7.2 12.6 9.9 8.1 7.1 5.9 10.5 7.4 13.4 7.5 6.4 16.8 9.0 4.8 108.7 14.4 8.3 7.4 8.5 9.4 8.3 9.0 10.2 8.1 4.5 69.1 7.3 7.0 7.4 15.3 13.3 7.5 13.0 9.5 9.8 8.3 10.6 10.0 11.4 9.0 10.8 27.4 7.3 9.8 3.4 11.3 13.9 17.2 13.8 7.1 12.5 6.7 23.4 15.6 40.9 7.5 6.0 24.5 11.2 12.0 11.6 9.8 9.0 6.2 8.3 12.9 9.2 8.4 8.6 9.0 16.6 38.1 8.9 9.7 11.8 16.9 20.8 11.2 6.4 8.3 54.7 12.2 6.9 24.6 7.0 8.8 14.1 10.6 12.7 11.3 16.4 9.0 14.3 25.5 11.4 19.2 25.3 10.4 7.7 11.3 1.5 2.2 2.0 1.0 2.5 1.9 1.8 1.4 1.6 0.9 1.8 0.9 0.8 1.9 1.5 0.2 2.0 1.5 9.7 8.8 23.4 14.6 8.5 9.7 12.6 9.9 13.4 8.5 10.2 15.3 7.6 16.0 15.6 27.4 2.4 5.9 2.0 2.3 1.8 9.0 6.7 4.3 79.6 0.0 8.4 3.7 16.7 2.4 2.5 4.8 1.9 1.7 5.9 5.0 6.5 7.1 6.6 3.0 43.9 1.3 1.4 6.6 8.2 6.0 5.1 4.6 5.7 3.9 1.4 18.5 37.9 4.4 0.0 3.5 4.4 8.3 7.2 4.2 5.4 18.7 2.2 4.8 3.1 30.2 42.8 2.1 1.3 5.7 2.0 3.7 3.4 2.5 4.6 9.6 0.0 3.5 3.7 3.8 4.2 4.3 7.4 2.6 3.5 5.2 3.9 3.2 DDIAS "C11orf82, FLJ25416, FLJ38838, noxin" ENSG00000165490 "DNA damage induced apoptosis suppressor" Q8IXT1 11 82899975-82958277 "Predicted intracellular proteins" "Apoptosis, Cell cycle, Growth arrest" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 7.9;testis: 10.8" "Cell type enhanced" "Detected in many" "Plasma cells: 8.2;Spermatocytes: 17.2;Spermatogonia: 18.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA038540, HPA038541" Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA038540: AB_10672648, HPA038541: AB_2676071" "unprognostic (2.53e-1)" "unprognostic (2.27e-1)" "unprognostic (5.04e-3)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" "unprognostic (5.32e-2)" "unprognostic (3.86e-6)" "unprognostic (4.65e-3)" "unprognostic (1.01e-3)" "unprognostic (8.24e-3)" "unprognostic (2.04e-4)" "unprognostic (4.72e-2)" "unprognostic (1.11e-16)" "unprognostic (7.17e-3)" "unprognostic (9.59e-2)" "unprognostic (1.89e-1)" "unprognostic (9.13e-2)" 0.9 0.4 0.6 3.3 0.9 7.9 2.1 0.9 1.0 0.7 0.4 1.8 1.6 1.2 1.0 2.9 0.5 0.7 0.5 0.8 0.4 0.4 1.2 3.4 4.4 0.8 0.8 0.5 0.9 0.1 0.1 1.9 0.7 0.5 2.2 0.5 0.8 0.4 1.0 2.2 1.5 1.8 0.5 2.9 0.9 10.8 0.8 5.3 0.4 0.9 6.2 3.5 0.9 1.8 13.6 22.6 21.0 15.2 1.9 3.1 15.3 25.4 10.5 26.8 31.0 22.4 16.2 16.1 36.1 5.7 21.6 24.7 36.0 15.5 36.8 30.7 19.7 23.1 10.6 9.1 0.2 28.6 19.7 0.7 1.4 33.8 15.6 2.3 12.8 20.5 23.9 27.0 23.9 19.6 27.0 23.2 25.1 36.5 24.4 20.0 40.5 20.6 5.7 23.3 15.6 21.5 15.2 15.6 5.7 20.2 16.5 11.7 6.0 26.7 35.9 71.1 30.4 15.4 44.3 56.4 8.4 20.2 26.3 0.7 10.3 4.1 0.5 7.9 0.2 1.1 0.3 0.7 4.5 1.7 0.6 0.4 5.5 2.2 8.5 1.4 0.5 3.2 0.6 0.9 0.9 1.0 0.8 0.4 0.8 0.8 0.7 0.5 0.8 1.8 0.3 0.0 0.0 0.0 4.3 0.0 0.6 0.0 1.8 0.0 1.1 1.1 0.9 1.5 0.0 0.0 0.0 2.7 1.0 0.6 0.0 0.9 4.2 1.0 0.6 0.8 0.0 6.5 0.6 0.6 5.5 0.8 1.1 1.2 0.0 2.5 0.7 0.7 2.5 0.0 0.3 0.7 0.0 6.4 0.0 1.9 0.3 3.5 0.0 1.9 4.5 0.0 4.1 0.5 0.6 0.5 0.1 0.7 8.2 0.7 0.3 0.3 0.0 0.0 0.0 0.8 1.1 17.2 18.2 5.4 0.0 0.3 1.5 0.5 1.6 0.9 DDR2 "NTRKR3, TKT, TYRO10" ENSG00000162733 "Discoidin domain receptor tyrosine kinase 2" Q16832 1 162631373-162787405 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" Osteogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Dwarfism, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 89.8;Fibroblasts: 116.5;Leydig cells: 63.0;Peritubular cells: 88.4;Skeletal myocytes: 98.2;Smooth muscle cells: 78.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 233.3;ASC TERT1: 214.4;BJ hTERT+: 163.4;fHDF/TERT166: 137.6;HSkMC: 157.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA070112 Approved "Plasma membrane,Actin filaments" Yes No 770000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Actin filaments" "HPA070112: AB_2686229" "unprognostic (4.12e-2)" "unprognostic (2.73e-1)" "unprognostic (6.97e-3)" "unprognostic (4.52e-2)" "unprognostic (1.17e-1)" "unprognostic (8.16e-2)" "unprognostic (1.81e-1)" "unprognostic (1.19e-1)" "unprognostic (6.62e-2)" "unprognostic (2.24e-2)" "unprognostic (1.00e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.73e-7)" "unprognostic (1.56e-3)" "unprognostic (8.26e-3)" "unprognostic (7.57e-2)" "unprognostic (4.10e-3)" 59.8 64.3 13.2 15.8 11.3 0.3 25.2 10.4 9.2 33.7 51.5 54.7 5.8 26.2 13.2 18.1 22.4 23.8 24.1 12.6 24.5 6.4 5.4 14.5 9.1 37.0 22.1 37.4 3.7 2.5 5.4 10.6 31.7 17.3 14.1 5.1 9.8 29.2 4.9 9.7 17.6 42.8 17.8 5.8 20.4 3.9 21.0 3.3 12.9 19.3 6.9 23.2 23.6 25.2 0.3 0.0 0.2 63.2 233.3 214.4 1.0 92.2 163.4 41.5 56.8 0.0 0.2 0.0 0.1 137.6 8.9 0.1 0.3 0.4 54.0 42.9 0.3 0.0 0.4 0.1 103.9 0.2 0.2 157.0 0.4 73.1 2.2 65.8 46.0 0.4 0.6 16.8 36.9 0.1 0.0 0.3 0.4 0.1 0.3 0.1 24.1 0.7 0.2 0.2 0.3 35.4 0.2 0.1 2.9 3.6 0.2 0.3 2.1 58.5 13.8 29.1 12.6 2.6 4.0 0.1 56.3 0.1 62.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.2 11.3 10.4 9.2 12.6 24.5 37.0 22.1 31.7 17.8 21.0 25.2 23.4 3.2 2.3 53.2 2.5 12.6 3.9 0.8 1.2 3.0 6.0 15.6 31.3 1.5 1.1 0.0 0.0 0.5 1.7 3.2 0.0 0.4 8.9 5.0 89.8 22.3 1.2 0.0 13.1 1.8 0.5 116.5 2.6 8.2 1.3 16.7 30.0 3.5 1.2 0.0 26.2 1.0 0.0 1.9 19.3 7.1 63.0 3.1 23.2 29.0 0.0 16.5 2.1 6.0 5.6 1.8 4.4 88.4 5.6 5.9 1.2 2.1 2.4 3.0 39.5 98.2 78.3 1.0 0.9 2.0 8.7 1.0 2.5 34.2 0.8 4.2 DDX58 "DKFZp434J1111, FLJ13599, RIG-1, RIG-I, RIG1" ENSG00000107201 "DExD/H-box helicase 58" O95786 9 32455302-32526208 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Antiviral defense, Host-virus interaction, Immunity, Innate immunity" "Helicase, Hydrolase, RNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 41.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.3" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 4 "BJ hTERT+ SV40 Large T+: 79.0;BJ hTERT+ SV40 Large T+ RasG12V: 76.0;GAMG: 22.8" "CAB012643, HPA047193, HPA073217" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 1: Neutrophils - Mixed function" "Cluster 16: Immune cells - Immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB012643: , HPA047193: AB_2679978, HPA073217: " "unprognostic (1.10e-1)" "unprognostic (4.65e-2)" "unprognostic (6.56e-2)" "prognostic unfavorable (5.46e-4)" "unprognostic (2.45e-1)" "unprognostic (2.37e-1)" "unprognostic (8.15e-2)" "unprognostic (4.57e-2)" "unprognostic (2.82e-1)" "unprognostic (6.48e-3)" "unprognostic (1.00e-2)" "unprognostic (3.35e-1)" "prognostic unfavorable (4.66e-4)" "unprognostic (2.22e-2)" "unprognostic (3.68e-2)" "unprognostic (1.05e-2)" "unprognostic (1.26e-1)" 6.3 4.9 3.5 7.5 2.9 1.3 6.0 3.0 4.3 7.1 3.1 6.3 2.9 5.6 4.7 6.4 4.4 6.0 4.1 2.7 3.6 5.5 6.3 7.1 7.4 5.2 3.7 4.6 5.7 2.5 5.2 5.7 4.0 4.2 5.3 2.3 10.0 3.5 4.8 7.8 7.1 5.7 6.5 9.2 4.8 2.8 3.6 15.6 4.3 1.7 5.2 5.1 5.3 2.9 4.3 2.4 2.5 2.2 7.5 6.4 2.7 2.1 14.6 79.0 76.0 2.4 1.4 0.4 2.7 2.7 22.8 2.8 2.3 1.3 11.4 7.4 0.9 1.1 2.4 3.5 5.0 1.4 4.5 4.9 1.3 6.9 1.3 4.2 14.3 1.5 1.8 1.0 6.6 0.6 3.8 12.4 1.8 0.6 2.0 2.4 3.1 0.0 11.6 0.6 2.0 0.3 1.7 1.7 12.6 1.7 3.5 0.9 13.4 1.5 0.9 1.7 1.1 0.0 0.3 0.9 2.6 3.3 2.1 0.0 0.1 0.3 0.2 0.1 0.3 0.2 0.3 0.0 0.0 0.2 0.2 0.2 1.3 0.4 0.2 0.0 0.2 0.0 3.5 2.9 3.0 4.3 2.7 3.6 5.2 3.7 4.0 6.5 3.6 2.9 41.7 22.4 8.8 20.5 13.9 4.2 5.1 7.2 13.6 4.1 5.8 5.1 5.1 5.7 6.7 1.8 2.1 5.6 13.9 13.8 0.0 19.5 2.7 12.9 8.7 23.6 3.0 5.7 10.4 12.2 7.6 13.9 21.9 20.3 5.1 16.8 9.3 6.7 5.6 6.7 13.2 4.6 4.1 7.3 4.6 0.4 6.5 11.6 0.0 39.4 12.3 6.4 21.6 31.2 17.5 16.2 7.7 6.0 9.1 4.9 16.9 7.2 7.3 2.5 6.6 16.8 13.1 0.5 2.3 10.9 5.4 2.5 17.8 10.4 2.6 5.3 DDX60L FLJ31033 ENSG00000181381 "DExD/H-box 60 like" Q5H9U9 4 168356735-168537786 "Enzymes, Predicted intracellular proteins" "Helicase, Hydrolase, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 51.1" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 32.8" "Group enriched" "Detected in all" 4 "granulocytes: 32.8;monocytes: 13.1" "Cell line enhanced" "Detected in many" "BJ hTERT+ SV40 Large T+: 44.0" "HPA043211, HPA055501" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA043211: AB_10794390, HPA055501: AB_2682838" "unprognostic (8.86e-2)" "unprognostic (2.77e-1)" "unprognostic (1.16e-1)" "unprognostic (2.45e-1)" "unprognostic (2.38e-1)" "unprognostic (3.20e-2)" "unprognostic (1.05e-1)" "unprognostic (7.94e-2)" "unprognostic (1.78e-1)" "unprognostic (4.19e-2)" "prognostic unfavorable (3.04e-5)" "unprognostic (1.70e-1)" "prognostic unfavorable (2.94e-4)" "unprognostic (1.13e-1)" "unprognostic (8.80e-2)" "unprognostic (8.93e-2)" "unprognostic (1.69e-1)" 6.9 2.8 2.9 15.8 3.1 51.1 5.8 2.4 4.4 6.6 3.5 9.1 8.7 6.7 2.1 3.2 5.4 9.2 3.5 2.4 5.0 2.2 8.2 10.1 9.6 9.6 3.9 5.3 3.1 3.0 0.4 20.7 5.5 3.8 9.0 6.3 9.0 3.2 1.0 3.0 11.0 7.4 9.3 12.8 13.5 2.2 7.8 15.5 3.5 3.6 7.3 5.9 0.7 5.7 12.3 7.1 2.7 1.1 6.9 19.9 13.3 12.0 25.3 44.0 30.4 0.1 28.0 0.2 0.6 12.2 23.9 4.7 1.2 7.3 12.8 7.0 1.0 27.0 8.1 0.7 8.4 11.1 6.5 5.6 2.1 15.9 1.4 9.2 31.5 6.0 0.5 0.3 28.6 0.3 10.0 7.0 0.6 1.1 5.9 5.4 6.1 0.0 4.2 7.1 0.5 3.6 21.4 2.6 12.2 0.5 1.9 15.3 34.1 2.4 15.6 5.6 4.2 11.2 1.9 0.1 7.8 32.2 3.4 2.4 5.9 5.4 3.7 9.1 5.1 1.2 3.7 3.8 3.6 2.0 2.9 3.3 32.8 2.7 13.1 0.0 5.5 2.5 2.9 3.1 2.4 4.4 2.4 5.0 9.6 3.9 5.5 9.3 7.8 5.7 29.0 9.6 6.7 11.4 14.7 1.0 2.6 3.9 3.4 1.7 11.2 3.3 8.3 2.8 5.1 3.7 22.9 6.1 16.0 24.0 0.0 7.6 15.7 8.5 15.6 18.9 0.0 5.9 1.5 10.1 39.4 13.0 44.4 7.1 8.8 20.3 6.1 6.6 26.1 0.0 5.5 14.1 10.2 23.8 6.0 4.4 3.4 46.2 0.0 33.7 35.6 2.9 24.7 28.6 2.4 26.4 31.5 4.1 6.0 2.1 13.2 3.7 11.5 19.4 6.6 7.1 5.7 0.7 1.4 4.3 2.4 7.1 24.1 12.2 4.5 2.0 DFFA "DFF-45, DFF1, DFF45, ICAD" ENSG00000160049 "DNA fragmentation factor subunit alpha" O00273 1 10456522-10472529 "Plasma proteins, Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002679, HPA018859, HPA019938, HPA025230" Supported Supported "Plasma membrane,Cytosol" NA NA 8700 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "CAB002679: , HPA018859: AB_1847622, HPA019938: AB_1847625, HPA025230: AB_1847623" "unprognostic (1.23e-1)" "unprognostic (2.63e-1)" "unprognostic (1.06e-1)" "unprognostic (3.59e-2)" "unprognostic (1.57e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (9.46e-4)" "unprognostic (1.55e-1)" "unprognostic (9.24e-3)" "unprognostic (3.57e-2)" "unprognostic (1.50e-1)" "unprognostic (1.91e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.21e-2)" "unprognostic (3.46e-2)" "unprognostic (3.89e-2)" "unprognostic (1.88e-1)" 13.3 12.6 15.0 12.0 18.0 6.5 12.6 19.7 16.5 11.1 14.2 11.3 12.1 11.7 9.8 16.7 13.0 10.8 12.1 14.9 17.2 16.8 13.2 11.3 12.4 17.4 18.7 15.3 11.4 18.0 9.2 20.1 17.5 11.8 12.2 12.2 10.9 12.3 12.3 10.9 11.1 16.1 16.1 10.7 12.1 9.8 18.3 13.3 12.3 13.9 16.2 14.4 10.1 18.3 37.8 36.8 31.0 35.4 25.7 24.3 15.1 52.5 33.6 53.4 39.6 88.4 48.4 79.9 33.1 44.5 29.7 30.3 60.5 62.2 53.7 31.9 41.8 39.9 37.6 35.8 41.8 49.3 25.4 30.5 30.6 84.4 67.4 29.1 41.3 39.3 72.6 17.6 38.4 48.0 48.8 22.2 27.2 28.3 42.4 41.3 37.1 40.1 48.5 28.6 36.5 35.6 48.9 42.1 58.0 26.6 27.0 17.0 43.4 24.9 34.0 46.4 35.0 21.6 32.5 114.3 26.5 45.7 38.5 1.8 11.2 8.6 15.2 9.1 11.7 16.6 10.3 13.5 10.6 15.8 10.7 13.0 1.4 17.5 12.3 12.4 16.2 10.5 15.0 18.0 19.7 16.5 14.9 17.2 17.4 18.7 17.5 16.1 18.3 18.3 26.9 44.8 34.3 3.3 23.5 34.4 39.0 43.8 30.1 21.1 20.5 25.0 23.7 32.9 36.6 18.4 108.4 91.1 22.8 12.6 37.2 46.5 32.0 22.4 31.6 34.0 34.2 15.6 6.5 39.1 64.9 25.1 20.9 23.8 24.7 35.6 31.4 31.0 41.8 20.2 8.3 17.3 28.5 22.9 13.8 73.2 30.1 17.0 10.6 3.7 37.4 23.3 28.8 5.0 6.9 49.1 10.6 32.4 19.3 48.1 25.0 57.8 26.0 34.0 19.7 29.9 26.9 35.7 28.4 32.0 40.6 66.4 18.5 43.9 27.9 38.9 DGKG DAGK3 ENSG00000058866 "Diacylglycerol kinase gamma" P49619 3 186105668-186362234 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.2" "Cell type enhanced" "Detected in many" "Astrocytes: 223.0;Excitatory neurons: 111.0;Inhibitory neurons: 63.5;Oligodendrocyte precursor cells: 334.8" "Cancer enhanced" "Detected in some" "glioma: 2.8" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "classical monocyte: 2.1;eosinophil: 1.2;intermediate monocyte: 1.2;myeloid DC: 1.5;neutrophil: 2.6;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "dendritic cells: 1.5;granulocytes: 2.6;monocytes: 2.1" "Cell line enhanced" "Detected in some" "HDLM-2: 23.9;HL-60: 7.7;U-266/84: 9.4;U-87 MG: 14.3;U-937: 7.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036577 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 6: Brain - Smell perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Vesicles, Plasma membrane" "HPA036577: AB_10672358" "unprognostic (2.23e-1)" "unprognostic (1.97e-1)" "unprognostic (1.56e-2)" "unprognostic (3.24e-5)" "unprognostic (2.70e-1)" "unprognostic (6.09e-4)" "unprognostic (1.21e-3)" "unprognostic (3.80e-2)" "unprognostic (5.88e-2)" "unprognostic (1.50e-1)" "unprognostic (1.94e-1)" "unprognostic (5.09e-2)" "unprognostic (8.05e-7)" "unprognostic (3.47e-3)" "unprognostic (7.19e-2)" "unprognostic (1.41e-1)" "unprognostic (9.16e-3)" 1.6 4.2 14.2 0.8 17.4 9.3 1.1 28.2 11.9 2.2 0.0 3.2 1.4 1.2 8.0 4.6 4.1 0.9 9.1 20.4 3.6 1.3 0.8 3.8 0.9 20.1 6.5 1.2 0.5 5.7 6.0 7.8 20.8 1.3 0.8 1.7 0.8 1.8 1.8 0.8 1.7 2.4 0.6 0.9 2.1 0.3 9.6 0.5 1.8 1.0 0.8 3.4 1.7 13.2 3.2 4.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.7 0.0 3.3 0.2 0.0 0.0 0.0 23.9 0.0 3.2 0.0 3.5 0.0 7.7 0.3 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.4 0.4 0.1 0.1 2.6 0.4 0.0 1.4 1.7 0.0 2.6 0.0 0.0 0.6 0.0 0.9 0.0 2.0 0.0 0.1 4.9 0.0 0.0 0.8 2.4 2.9 0.0 9.4 0.0 14.3 7.0 2.6 0.0 2.1 1.2 0.0 1.2 0.0 0.3 0.0 0.0 1.5 0.1 0.0 0.0 2.6 0.0 1.5 0.2 0.0 0.7 14.2 17.4 28.2 11.9 20.4 3.6 20.1 6.5 20.8 0.6 9.6 13.2 0.1 0.0 1.7 223.0 3.1 0.4 0.2 0.0 0.6 0.1 0.1 0.4 19.4 1.5 0.0 1.8 0.0 0.1 0.0 0.0 0.0 1.4 2.6 0.3 0.1 5.0 0.0 0.4 111.0 1.2 0.0 0.5 0.5 0.1 0.0 0.3 22.1 0.0 2.1 1.7 63.5 0.1 0.0 3.2 1.4 4.2 1.8 3.4 0.0 12.2 5.2 6.8 0.0 334.8 7.8 1.0 0.1 0.4 0.2 0.4 0.1 0.9 0.0 0.1 13.1 1.8 14.5 0.0 0.2 0.4 0.4 0.1 0.1 0.9 0.1 0.4 DGKH DGKeta ENSG00000102780 "Diacylglycerol kinase eta" Q86XP1 13 42040036-42256578 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 25.8" "Cell type enhanced" "Detected in all" "Prostatic glandular cells: 137.8;Urothelial cells: 147.3" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 25.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039533, HPA040355, HPA061538" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 10: Brain - Neuronal signaling" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA039533: AB_10795145, HPA040355: AB_10796452, HPA061538: " "unprognostic (2.80e-1)" "unprognostic (7.03e-2)" "unprognostic (1.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.55e-3)" "unprognostic (7.62e-2)" "unprognostic (1.04e-2)" "unprognostic (9.60e-2)" "unprognostic (7.00e-3)" "unprognostic (4.37e-2)" "unprognostic (1.86e-1)" "unprognostic (2.41e-1)" "unprognostic (3.43e-3)" "unprognostic (1.03e-1)" "unprognostic (1.67e-1)" "unprognostic (4.93e-2)" "unprognostic (1.43e-2)" 3.7 1.3 4.5 2.0 25.8 1.3 3.5 8.7 5.4 4.4 0.0 3.7 1.5 6.4 6.9 4.1 4.3 2.5 3.0 7.3 4.4 3.3 1.0 7.8 2.2 0.0 7.4 2.8 1.0 0.7 2.6 4.5 0.4 2.8 3.3 2.6 3.0 2.1 1.5 3.2 2.7 4.0 0.2 1.7 2.6 2.3 9.7 2.7 2.5 2.2 1.3 5.3 4.6 2.8 5.6 6.6 4.3 3.6 1.9 4.2 0.5 3.4 2.7 2.2 2.8 0.6 4.7 4.3 4.1 3.7 8.3 11.8 3.8 7.7 3.3 3.4 12.4 7.6 3.6 0.4 2.4 3.3 2.0 1.6 7.7 4.3 17.0 3.4 9.9 5.3 3.0 2.9 3.8 5.1 3.4 1.7 1.9 5.2 4.3 5.0 3.8 2.9 7.4 16.7 2.5 2.6 3.1 4.0 3.0 1.8 3.4 8.9 9.8 4.1 3.8 4.5 4.7 1.5 1.5 4.8 2.4 2.9 3.1 0.6 0.3 0.1 0.2 0.2 0.2 0.1 0.4 0.4 0.0 0.2 0.2 0.4 0.9 0.1 0.1 0.3 0.3 0.1 4.5 25.8 8.7 5.4 7.3 4.4 0.0 7.4 0.4 0.2 9.7 2.8 64.8 22.4 20.1 8.8 1.9 61.7 58.1 61.1 15.9 44.5 13.6 8.9 8.5 24.3 44.7 11.0 4.2 3.7 2.2 29.0 1.9 11.3 25.9 64.1 26.0 50.8 47.4 2.7 85.4 7.2 2.2 17.5 15.3 46.2 7.6 5.7 23.2 3.2 6.8 1.7 60.2 18.7 14.2 5.6 43.1 20.1 3.4 8.0 8.8 56.2 8.6 18.8 1.0 54.3 11.0 27.6 19.2 9.1 6.2 137.8 13.1 8.4 91.8 2.6 26.3 16.2 54.1 3.8 3.8 19.7 33.1 2.9 13.0 11.5 22.0 147.3 DIAPH1 "DFNA1, hDIA1, LFHL1" ENSG00000131504 "Diaphanous related formin 1" O60610 5 141515016-141619055 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Hearing Actin-binding "Cancer-related genes, Deafness, Disease variant, Epilepsy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 172.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HMC-1: 564.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004916, HPA076913" Approved Uncertain "Plasma membrane,Cytosol" NA NA 2000000 "Cluster 41: Basophils - Cellular respiration" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA004916: AB_1847668, HPA076913: " "unprognostic (6.79e-2)" "unprognostic (2.99e-1)" "unprognostic (2.12e-3)" "unprognostic (3.73e-2)" "unprognostic (4.18e-2)" "unprognostic (1.54e-1)" "unprognostic (2.08e-1)" "unprognostic (4.54e-3)" "unprognostic (2.03e-1)" "unprognostic (1.27e-2)" "prognostic unfavorable (7.81e-5)" "unprognostic (2.88e-3)" "prognostic favorable (1.29e-5)" "unprognostic (1.64e-2)" "unprognostic (1.84e-2)" "unprognostic (7.00e-2)" "unprognostic (1.65e-1)" 27.9 20.3 21.0 42.1 22.5 90.2 24.2 18.3 20.9 24.4 40.0 31.0 40.6 18.5 44.3 58.0 25.2 30.0 34.9 21.5 25.7 38.1 91.7 51.3 67.0 18.8 19.9 12.9 37.3 44.6 24.5 25.1 20.1 14.7 31.1 28.4 36.1 19.3 172.0 47.3 36.5 18.7 18.0 36.3 45.1 19.9 27.4 68.5 33.1 55.7 66.4 47.1 30.4 18.6 147.8 92.6 53.2 68.4 40.4 54.5 71.3 59.5 62.2 67.7 70.2 318.1 131.6 156.5 88.1 85.5 103.0 157.9 116.9 191.5 84.8 88.9 66.6 282.6 121.4 103.6 37.7 198.9 564.7 34.4 102.1 94.5 95.5 30.5 87.0 234.8 101.2 106.9 67.7 141.5 217.2 256.8 51.6 75.2 61.6 240.1 87.1 87.6 129.8 158.5 69.4 37.3 146.2 184.6 59.5 47.5 77.5 92.1 52.8 93.9 49.9 52.1 119.9 54.2 94.4 111.7 50.2 153.7 57.8 23.6 12.8 29.8 32.6 14.0 21.2 9.3 20.3 25.3 12.6 9.1 14.8 23.9 13.7 13.7 15.1 10.0 18.7 15.4 21.0 22.5 18.3 20.9 21.5 25.7 18.8 19.9 20.1 18.0 27.4 18.6 33.9 48.1 46.8 11.8 40.0 52.6 60.8 22.4 21.6 17.3 35.1 23.1 18.6 22.8 48.0 44.1 54.2 20.9 96.9 60.5 5.9 62.7 27.9 42.3 18.9 39.0 5.4 52.6 44.1 98.0 31.9 25.9 76.0 83.0 46.9 14.5 16.8 91.6 17.1 6.7 33.6 23.1 12.2 38.4 60.6 9.0 11.8 78.5 19.6 24.4 54.6 12.1 115.4 25.6 9.1 122.9 35.7 10.9 54.1 77.3 35.2 13.9 30.4 69.0 13.1 15.4 26.4 18.3 26.1 38.7 59.7 52.1 92.8 18.3 30.1 91.2 DIAPH3 "AN, AUNA1, DRF3, FLJ34705, NSDAN" ENSG00000139734 "Diaphanous related formin 3" Q9NSV4 13 59665583-60163928 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes, Deafness, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 7.1;testis: 18.9" "Cell type enriched" "Detected in many" 5 "Early spermatids: 414.4" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032151 Supported "Plasma membrane,Microtubules" NA Yes "Cluster 23: Testis - Cell cycle regulation" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Microtubules" "HPA032151: AB_2674181" "unprognostic (3.78e-2)" "unprognostic (1.28e-2)" "prognostic favorable (9.04e-4)" "prognostic unfavorable (4.18e-4)" "unprognostic (2.78e-1)" "unprognostic (4.69e-2)" "unprognostic (1.27e-4)" "prognostic unfavorable (3.72e-4)" "unprognostic (1.74e-2)" "unprognostic (2.19e-1)" "unprognostic (5.22e-5)" "unprognostic (3.59e-3)" "unprognostic (5.31e-5)" "unprognostic (4.30e-2)" "unprognostic (2.37e-1)" "unprognostic (4.07e-1)" "unprognostic (2.74e-3)" 0.4 0.1 0.1 1.7 0.2 7.1 0.8 0.3 0.3 0.3 0.2 1.9 1.9 0.6 0.0 2.1 0.1 0.4 0.1 0.1 0.2 0.8 0.2 1.2 2.4 0.2 0.3 0.1 0.2 0.1 0.0 3.5 0.2 0.1 2.1 0.0 0.5 0.0 0.0 1.3 1.6 2.6 0.1 0.5 1.6 18.9 0.3 5.4 0.1 0.0 2.4 0.6 0.7 0.2 47.7 15.6 15.8 9.1 2.7 7.1 26.9 65.0 28.7 64.2 55.6 41.7 31.4 15.9 5.2 33.4 16.7 31.7 26.0 25.5 96.9 18.0 17.9 22.7 37.6 9.5 4.1 31.2 17.4 2.8 0.6 39.2 26.3 16.3 29.2 14.0 17.8 21.9 61.8 6.9 28.0 10.2 14.7 22.5 8.9 18.8 38.9 12.9 19.9 9.6 8.3 14.3 33.2 22.8 9.5 33.8 16.7 16.8 29.3 40.5 25.9 13.7 54.5 14.7 17.1 24.4 10.9 15.2 31.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.3 0.3 0.1 0.2 0.2 0.3 0.2 0.1 0.3 0.2 0.6 54.5 3.4 39.8 1.9 3.7 0.8 2.1 2.8 0.0 3.9 1.5 1.0 2.8 1.8 0.0 0.0 21.1 1.1 3.8 5.9 1.3 414.4 2.5 3.5 2.1 0.0 26.7 5.6 4.0 30.7 5.8 9.7 9.3 0.0 78.8 1.8 0.4 6.1 0.0 3.3 2.6 2.0 1.0 1.2 56.0 0.6 1.5 0.0 5.6 0.1 3.5 2.1 19.1 1.8 1.5 0.2 0.0 18.9 0.4 1.1 5.4 0.2 0.0 0.0 0.0 7.9 39.2 17.8 11.6 1.1 7.3 2.2 2.8 5.6 1.5 DLG1 "dJ1061C18.1.1, DLGH1, hdlg, SAP-97, SAP97" ENSG00000075711 "Discs large MAGUK scaffold protein 1" Q12959 3 197042560-197299330 "Predicted intracellular proteins, Transporters" "Host-virus interaction" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 422.9;Oligodendrocytes: 1542.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016307, HPA069593" Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Vesicles "Plasma membrane" "CAB016307: AB_2092015, HPA069593: " "unprognostic (2.04e-2)" "unprognostic (1.37e-1)" "unprognostic (7.79e-2)" "unprognostic (4.56e-3)" "unprognostic (3.54e-2)" "unprognostic (8.56e-2)" "unprognostic (8.90e-3)" "unprognostic (2.97e-1)" "unprognostic (5.98e-2)" "unprognostic (2.33e-1)" "unprognostic (2.41e-2)" "unprognostic (3.40e-2)" "unprognostic (1.70e-3)" "unprognostic (3.56e-1)" "unprognostic (2.46e-1)" "unprognostic (1.33e-1)" "unprognostic (3.07e-1)" 20.7 14.5 26.4 14.7 57.0 16.2 18.4 33.2 36.4 23.8 15.4 24.2 24.0 19.7 11.6 37.6 16.1 17.1 19.4 25.4 29.3 27.6 25.9 18.0 14.7 36.9 43.3 23.3 17.2 31.7 14.4 21.3 34.8 15.9 26.3 38.8 20.2 18.6 25.2 18.8 25.4 21.2 19.9 13.0 22.9 15.5 50.3 27.1 43.3 28.2 20.6 20.3 20.5 73.5 128.0 20.0 40.3 75.7 34.2 36.2 40.7 52.2 46.2 49.2 59.0 60.4 59.8 41.5 127.1 47.7 95.7 86.4 39.3 76.4 97.7 10.9 22.5 35.2 31.1 40.5 35.2 35.0 33.3 27.8 43.3 49.1 101.3 163.1 64.8 32.2 26.7 51.4 125.6 41.5 51.3 12.9 35.3 71.1 35.4 26.7 51.6 26.8 51.9 55.3 19.7 32.3 72.9 49.5 49.4 46.7 108.8 26.0 62.5 127.5 33.5 36.1 79.9 76.0 50.6 50.6 50.3 51.8 40.0 2.5 0.7 1.2 0.8 0.7 1.3 1.6 1.3 0.9 0.8 1.2 1.3 1.3 2.4 1.1 0.4 1.1 1.0 0.8 26.4 57.0 33.2 36.4 25.4 29.3 36.9 43.3 34.8 19.9 50.3 73.5 24.0 25.6 25.7 113.3 28.5 53.3 52.3 45.5 40.5 42.0 29.6 23.0 25.6 35.8 44.6 49.7 95.9 48.9 25.2 72.4 5.9 22.8 12.9 51.8 37.4 28.1 28.9 17.5 422.9 20.2 19.5 27.7 51.5 68.5 12.0 29.9 27.8 54.6 14.9 37.0 117.8 34.4 28.5 26.4 26.0 19.2 28.6 19.2 37.4 165.8 18.3 71.9 43.3 257.3 1542.2 30.3 48.0 25.6 34.1 52.3 50.6 20.8 66.3 101.7 13.1 40.5 25.5 31.2 37.9 66.7 70.8 25.0 30.6 29.3 38.8 106.8 DLG2 "chapsyn-110, PPP1R58, PSD-93, PSD93" ENSG00000150672 "Discs large MAGUK scaffold protein 2" Q15700 11 83455012-85627922 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 88.4" "Group enriched" "Detected in many" 4 "Excitatory neurons: 3292.3;Inhibitory neurons: 2602.7;Oligodendrocyte precursor cells: 2331.8;Oligodendrocytes: 4213.8" "Cancer enhanced" "Detected in some" "glioma: 1.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 8.2;SH-SY5Y: 8.1;T-47d: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA021307, HPA023896, CAB072341" Enhanced Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Vesicles "CAB072341: , HPA021307: AB_1846625, HPA023896: AB_2671353" "unprognostic (2.61e-3)" "unprognostic (2.81e-2)" "unprognostic (4.05e-2)" "unprognostic (9.03e-2)" "unprognostic (3.25e-1)" "unprognostic (1.09e-1)" "unprognostic (9.44e-3)" "unprognostic (7.78e-2)" "unprognostic (4.32e-1)" "unprognostic (4.61e-2)" "unprognostic (9.28e-3)" "unprognostic (4.84e-1)" "unprognostic (7.66e-6)" "unprognostic (2.92e-2)" "unprognostic (2.41e-1)" "unprognostic (6.52e-2)" "unprognostic (8.89e-2)" 1.6 11.0 29.5 1.1 48.7 0.3 2.1 3.6 55.8 1.8 0.0 2.3 1.2 2.9 4.1 7.5 5.7 2.1 3.0 64.4 18.1 3.6 2.8 1.7 1.1 13.5 8.2 5.7 3.3 7.3 10.0 2.4 10.3 4.0 1.4 25.4 3.1 4.6 0.8 20.2 1.2 2.2 11.9 2.5 1.5 8.1 10.5 7.3 15.5 0.7 2.9 1.7 2.6 88.4 0.6 0.3 0.9 0.5 0.6 0.7 8.2 0.2 0.5 0.4 0.3 7.4 1.1 1.3 1.3 0.4 0.5 0.8 2.3 0.7 0.4 0.8 0.9 1.3 5.0 0.2 0.1 0.4 1.1 0.5 0.5 1.0 1.0 0.4 0.5 1.9 1.2 3.5 0.7 0.9 0.6 1.3 6.0 0.8 1.3 1.4 2.0 0.9 0.4 0.3 5.9 8.1 0.8 5.1 0.4 7.2 21.2 0.0 0.3 2.2 1.8 2.1 0.3 0.8 2.9 5.6 0.8 0.7 0.2 0.0 0.0 0.2 0.1 0.0 0.5 0.1 0.1 0.2 0.0 0.6 0.6 0.2 0.0 0.0 0.1 0.5 0.0 0.0 29.5 48.7 3.6 55.8 64.4 18.1 13.5 8.2 10.3 11.9 10.5 88.4 7.0 3.2 10.4 742.8 1.3 3.3 3.6 0.3 9.1 298.1 4.4 5.2 8.3 2.8 1.8 7.3 275.2 7.9 1.8 1.5 9.8 0.7 21.5 1.3 2.7 3.6 4.2 0.0 3292.3 0.4 0.5 7.4 1.1 2.4 0.0 1.6 2.2 4.6 4.0 23.5 2602.7 1.1 0.0 0.3 0.0 16.4 7.8 0.8 1.8 487.2 0.6 11.0 0.0 2331.8 4213.8 0.4 0.1 6.4 0.1 2.0 0.6 2.7 0.9 48.2 6.6 7.1 4.1 11.3 3.2 6.2 8.5 2.1 1.7 12.1 0.9 0.8 DMWD "D19S593E, DMR-N9, gene59" ENSG00000185800 "DM1 locus, WD repeat containing" Q09019 19 45782947-45792845 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 60.5;Late spermatids: 57.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA068172, HPA069843" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Actin filaments" "HPA068172: AB_2685964, HPA069843: AB_2686212" "unprognostic (6.49e-2)" "unprognostic (3.35e-1)" "unprognostic (1.03e-2)" "unprognostic (1.65e-3)" "unprognostic (3.10e-2)" "unprognostic (2.39e-1)" "prognostic unfavorable (1.47e-4)" "unprognostic (5.11e-3)" "unprognostic (7.61e-2)" "unprognostic (7.26e-3)" "unprognostic (1.31e-2)" "unprognostic (2.16e-1)" "unprognostic (1.81e-1)" "unprognostic (1.85e-1)" "unprognostic (1.97e-1)" "unprognostic (1.18e-2)" "unprognostic (4.59e-2)" 24.6 19.1 27.7 12.3 23.4 7.3 23.0 10.5 31.7 29.1 10.8 40.3 9.7 39.6 6.7 18.2 29.4 11.8 43.1 30.0 18.6 18.7 10.2 22.6 11.2 17.5 19.9 29.1 18.1 10.3 29.6 15.0 15.1 25.2 7.4 11.9 17.1 12.2 44.0 15.5 18.3 14.8 8.9 17.0 25.0 36.5 20.2 10.3 23.1 20.1 7.1 30.6 23.2 14.5 31.6 34.3 30.4 21.2 18.1 22.9 23.3 26.9 18.8 23.5 21.2 20.6 17.1 13.2 15.4 30.4 28.8 23.4 16.1 13.4 12.3 38.6 30.0 11.4 37.3 18.2 22.4 1.4 17.6 21.5 16.2 22.0 31.2 26.7 20.3 8.3 28.2 28.9 18.6 25.8 16.0 9.0 13.8 20.6 22.2 16.3 11.0 14.5 14.6 29.7 30.4 33.6 28.9 22.2 19.5 13.4 19.4 7.7 43.3 27.0 26.6 18.1 40.7 41.1 27.4 15.0 28.1 2.1 31.8 0.6 0.2 0.2 1.4 0.6 1.1 0.6 1.2 1.1 0.2 1.4 0.4 0.8 0.6 1.8 0.8 0.2 0.7 0.3 27.7 23.4 10.5 31.7 30.0 18.6 17.5 19.9 15.1 8.9 20.2 14.5 18.8 6.4 4.7 8.1 6.9 8.4 13.9 4.5 2.2 34.5 11.8 9.8 28.5 10.0 4.4 9.2 60.5 7.3 10.6 10.4 5.9 7.3 17.2 12.4 18.9 16.2 26.3 9.3 8.1 10.6 9.6 15.3 6.1 11.2 11.4 23.3 20.0 4.6 2.0 52.2 7.5 7.9 10.2 4.8 11.4 57.7 17.1 2.6 5.4 5.6 0.9 23.3 14.4 10.1 5.8 13.8 7.2 17.0 6.8 11.5 5.6 7.1 8.9 41.2 13.1 24.5 19.0 10.8 15.7 4.6 7.0 5.5 9.0 20.6 8.1 11.5 DNAAF4 "CILD25, DYX1C1, EKN1, FLJ37882" ENSG00000256061 "Dynein axonemal assembly factor 4" Q8WXU2 15 55410525-55508234 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Neurogenesis "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 27.5" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 171.5;Proximal tubular cells: 34.4;Respiratory ciliated cells: 102.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RPTEC TERT1: 17.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051048 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA051048: AB_2681325" "unprognostic (5.97e-4)" "unprognostic (3.60e-2)" "unprognostic (1.69e-1)" "unprognostic (7.45e-4)" "unprognostic (1.74e-1)" "unprognostic (5.30e-3)" "unprognostic (4.05e-2)" "unprognostic (3.08e-2)" "unprognostic (8.24e-2)" "unprognostic (2.91e-1)" "unprognostic (9.47e-2)" "unprognostic (1.75e-1)" "unprognostic (5.29e-2)" "unprognostic (3.85e-2)" "unprognostic (3.06e-2)" "unprognostic (1.34e-1)" "unprognostic (1.84e-1)" 1.0 2.0 4.7 1.1 4.7 1.2 3.3 3.6 6.8 2.8 8.4 0.9 0.6 3.7 10.6 1.2 11.1 2.2 1.0 4.8 5.8 5.0 0.5 4.3 1.1 5.1 5.0 2.6 2.1 8.5 3.5 0.7 3.8 2.0 0.9 27.5 1.5 2.0 0.8 1.7 0.8 2.0 3.6 1.3 1.0 11.3 6.7 0.7 8.6 0.5 0.9 1.4 0.7 3.7 7.0 4.8 4.9 10.4 2.0 3.5 1.5 1.0 2.6 3.2 3.6 1.0 2.9 0.6 4.4 2.1 5.2 2.1 1.9 2.7 3.7 2.4 2.5 2.6 3.2 1.7 1.8 5.4 4.2 2.2 5.7 7.6 2.9 5.1 7.2 2.2 0.8 0.3 4.8 2.9 1.3 4.7 2.9 11.0 3.7 1.1 2.3 0.9 17.6 2.3 4.9 10.7 4.3 1.3 6.5 4.2 6.2 1.4 2.5 5.0 2.5 4.4 5.2 2.1 5.4 1.7 8.3 1.3 1.5 0.1 0.7 0.5 0.3 0.5 0.3 1.4 0.5 0.5 0.6 1.3 0.7 0.5 1.4 0.4 0.5 1.9 0.7 0.3 4.7 4.7 3.6 6.8 4.8 5.8 5.1 5.0 3.8 3.6 6.7 3.7 4.1 12.8 15.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 7.9 9.8 0.0 0.0 15.5 12.9 0.0 2.0 0.4 0.0 5.9 13.6 0.0 171.5 9.0 2.8 0.0 0.0 0.0 5.1 1.5 3.4 0.0 13.3 2.5 9.7 0.0 0.0 19.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.4 0.0 0.0 34.4 102.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.5 0.7 7.2 0.0 0.0 DNAJA4 PRO1472 ENSG00000140403 "DnaJ heat shock protein family (Hsp40) member A4" Q8WW22 15 78264086-78282196 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 138.4;tongue: 144.6" "Group enriched" "Detected in many" 5 "Early spermatids: 673.9;Late spermatids: 1608.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 33.6;CAPAN-2: 43.3;HeLa: 47.3;MCF7: 33.6;RT4: 85.2;SCLC-21H: 53.3;SiHa: 42.7;THP-1: 39.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004646, HPA041790" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 15: RT4 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "CAB004646: AB_426011, HPA041790: AB_2677674" "unprognostic (8.41e-2)" "unprognostic (2.48e-1)" "unprognostic (3.00e-2)" "unprognostic (8.20e-3)" "unprognostic (1.14e-3)" "unprognostic (1.99e-1)" "unprognostic (2.28e-2)" "unprognostic (2.46e-1)" "unprognostic (5.86e-2)" "unprognostic (7.78e-2)" "unprognostic (2.31e-2)" "unprognostic (1.28e-1)" "prognostic favorable (1.08e-7)" "unprognostic (1.89e-1)" "unprognostic (2.84e-1)" "unprognostic (9.01e-2)" "unprognostic (2.93e-2)" 16.5 20.0 60.6 14.0 67.7 63.7 12.6 62.6 138.4 14.1 45.6 18.0 13.8 8.3 20.2 15.8 38.9 11.2 123.3 68.6 93.1 26.7 3.3 19.7 11.3 65.7 73.3 12.1 6.6 7.4 30.9 9.5 89.8 26.7 18.5 33.0 15.6 15.6 123.2 28.6 16.3 19.6 59.8 13.5 24.2 78.3 73.5 9.4 9.6 144.6 12.4 29.6 13.6 71.3 33.6 0.2 0.0 0.0 0.0 0.0 0.1 4.1 0.0 1.1 0.5 0.0 43.3 0.0 0.3 3.2 0.0 31.3 0.0 0.0 0.1 0.1 0.0 19.9 47.3 0.0 9.4 0.0 20.6 3.6 4.1 2.6 0.0 0.0 6.6 0.0 0.0 0.0 0.4 33.6 0.0 0.0 0.0 14.4 0.3 0.0 0.0 0.0 0.1 85.2 53.3 0.0 42.7 8.6 3.6 2.3 32.4 39.8 0.5 0.0 8.7 4.0 0.4 0.6 2.4 0.0 0.1 4.2 0.0 0.0 0.3 1.1 0.6 0.3 1.0 0.7 0.9 0.9 0.4 0.1 1.7 1.4 0.0 0.1 0.4 0.2 0.5 0.6 60.6 67.7 62.6 138.4 68.6 93.1 65.7 73.3 89.8 59.8 73.5 71.3 41.9 6.4 4.8 12.7 10.0 28.8 209.9 14.0 2.2 19.6 44.6 29.2 43.6 2.8 33.5 7.3 81.3 1.9 6.7 55.5 1.9 1.3 673.9 124.0 11.4 18.9 100.3 92.8 16.6 2.4 3.8 18.3 21.4 41.8 36.9 7.5 6.8 0.2 16.5 6.7 24.0 34.9 10.2 9.5 81.7 1608.0 10.2 51.7 51.6 6.5 3.5 10.3 6.2 15.1 19.0 5.1 55.3 11.3 3.7 115.8 15.8 7.2 138.9 22.6 6.6 17.4 20.2 33.8 27.7 16.9 46.7 6.8 37.1 6.9 42.1 190.1 DNAJC9 "JDD1, SB73" ENSG00000213551 "DnaJ heat shock protein family (Hsp40) member C9" Q8WXX5 10 73183362-73247255 "Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 91.9" "Cell type enhanced" "Detected in all" "Erythroid cells: 173.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035215, HPA035216" Supported Supported "Nucleoplasm,Plasma membrane" NA NA 39000 "Cluster 44: Non-specific - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA035215: AB_10603663, HPA035216: AB_2674522" "unprognostic (4.18e-2)" "unprognostic (1.61e-2)" "unprognostic (7.63e-2)" "unprognostic (2.67e-3)" "unprognostic (3.45e-1)" "unprognostic (6.83e-3)" "unprognostic (2.43e-3)" "prognostic unfavorable (3.26e-4)" "unprognostic (6.20e-2)" "unprognostic (1.66e-1)" "unprognostic (3.91e-1)" "prognostic unfavorable (7.07e-5)" "unprognostic (5.61e-2)" "unprognostic (3.08e-3)" "unprognostic (6.49e-2)" "unprognostic (3.38e-1)" "unprognostic (1.56e-1)" 9.2 10.6 17.1 17.6 17.5 91.9 15.4 19.2 21.5 11.2 15.4 16.0 14.6 12.8 12.4 16.9 9.7 6.9 8.6 16.9 17.0 10.0 13.4 9.6 28.2 16.4 16.5 15.3 8.7 10.2 10.6 17.6 16.9 11.4 18.0 25.1 11.3 11.2 11.5 17.7 13.9 11.8 15.7 14.8 12.2 12.4 17.0 35.8 8.4 13.1 32.3 11.5 11.9 17.6 135.0 77.3 93.8 68.4 16.1 19.3 45.7 101.5 59.4 101.1 106.1 130.8 89.4 86.9 33.5 43.6 43.7 83.1 92.9 67.5 118.1 98.5 63.8 188.3 79.4 93.4 14.8 173.1 71.0 14.8 33.2 107.1 93.4 36.4 66.2 112.1 168.3 103.0 81.4 118.4 155.0 124.7 36.3 64.4 215.1 114.2 85.1 47.6 52.9 61.5 44.3 73.4 73.5 114.5 52.9 43.7 62.1 76.8 48.0 65.2 118.3 71.3 168.0 45.0 70.6 141.8 64.8 162.9 45.9 23.9 3.7 29.1 25.5 10.7 29.2 32.8 31.3 28.2 6.5 28.3 30.3 26.9 4.5 24.8 10.9 20.3 36.8 18.0 17.1 17.5 19.2 21.5 16.9 17.0 16.4 16.5 16.9 15.7 17.0 17.6 17.3 9.6 12.3 11.1 39.5 47.7 34.1 31.9 33.0 26.1 21.5 24.8 2.7 17.2 24.8 9.2 8.4 107.8 44.6 18.3 21.5 31.5 80.4 15.9 14.0 20.6 12.0 173.8 11.8 31.4 111.4 17.6 12.2 19.0 42.3 26.0 13.9 9.8 61.9 15.2 12.8 25.6 54.9 10.9 19.6 43.3 14.0 17.4 32.0 6.5 23.0 29.5 32.0 7.5 6.5 44.1 16.7 20.3 49.7 27.6 18.2 16.3 21.9 43.2 26.3 17.7 28.3 28.7 65.4 38.2 43.5 58.0 45.2 19.7 38.0 37.5 DPYSL2 "CRMP2, DHPRP2, DRP-2, DRP2" ENSG00000092964 "Dihydropyrimidinase like 2" Q16555 8 26514031-26658178 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 7 "brain: 549.9" "Cell type enhanced" "Detected in all" "Adipocytes: 362.9;Oligodendrocytes: 367.2" "Cancer enhanced" "Detected in all" "glioma: 89.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 65.8;intermediate monocyte: 74.5;myeloid DC: 71.2;non-classical monocyte: 48.8;plasmacytoid DC: 42.2" "Group enriched" "Detected in all" 5 "dendritic cells: 71.2;monocytes: 74.5" "Cell line enhanced" "Detected in many" "ASC diff: 263.7;Karpas-707: 279.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002381, CAB018719" Supported Supported "Plasma membrane,Cytosol" NA NA 3200000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 2: Karpas-707 - Immune response" "Cluster 50: Fibroblasts - ECM organization" Cytosol "Plasma membrane" "CAB018719: AB_2085366, HPA002381: AB_1847244" "unprognostic (2.88e-2)" "unprognostic (1.01e-2)" "unprognostic (9.51e-2)" "unprognostic (3.16e-3)" "unprognostic (8.23e-2)" "unprognostic (1.68e-2)" "unprognostic (1.51e-1)" "unprognostic (9.95e-3)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" "unprognostic (1.79e-2)" "unprognostic (4.13e-2)" "unprognostic (5.58e-2)" "unprognostic (9.32e-3)" "unprognostic (1.23e-1)" "unprognostic (3.27e-2)" "prognostic unfavorable (5.41e-5)" 60.0 34.8 252.6 22.5 348.0 3.5 48.0 332.4 266.7 25.3 0.0 44.8 10.4 24.9 11.4 18.3 29.6 29.4 58.6 276.1 263.2 21.3 17.6 78.2 17.4 362.4 296.0 40.8 11.0 7.1 22.1 43.7 389.9 19.7 19.0 64.0 18.5 14.9 19.2 25.8 27.6 32.9 257.9 33.6 21.5 11.2 305.0 19.3 22.5 25.8 20.1 35.6 26.9 549.9 22.0 104.1 100.2 53.9 263.7 120.6 9.8 41.9 97.0 39.2 50.6 41.0 31.0 32.7 29.7 131.7 78.8 20.9 106.6 42.0 37.1 74.2 9.2 37.0 36.9 57.9 168.5 8.0 14.5 150.8 59.5 107.1 61.9 125.5 80.0 24.9 1.1 279.1 39.9 13.9 64.3 8.1 78.8 69.9 20.0 84.3 40.3 21.8 66.2 25.0 45.6 95.8 51.0 0.5 28.6 65.7 7.8 14.8 145.0 88.2 34.8 74.3 18.5 39.1 43.3 24.8 127.7 48.1 46.0 1.3 65.8 0.6 9.1 74.5 3.3 8.5 8.1 6.2 71.2 4.4 4.0 5.2 1.7 11.3 48.8 42.2 13.3 30.3 252.6 348.0 332.4 266.7 276.1 263.2 362.4 296.0 389.9 257.9 305.0 549.9 362.9 131.4 71.7 193.9 11.5 40.4 1.0 13.2 2.2 111.4 44.4 58.4 105.0 84.4 19.4 22.0 31.3 15.1 64.8 4.5 3.9 21.4 3.1 41.6 154.3 154.6 60.7 22.3 191.9 2.0 9.1 144.9 6.1 33.6 20.8 33.0 211.3 22.8 51.1 141.3 157.0 87.0 4.1 223.5 192.3 10.6 109.0 111.1 120.9 81.5 163.5 165.2 22.6 102.1 367.2 12.6 6.2 89.5 6.5 1.1 4.7 24.4 10.5 38.6 138.1 51.8 110.6 3.8 17.0 1.6 33.8 4.5 14.8 16.8 12.1 1.2 DRD1 ENSG00000184845 "Dopamine receptor D1" P21728 5 175440036-175444182 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 13 "brain: 21.3;retina: 8.4" "Group enriched" "Detected in some" 12 "Bipolar cells: 40.1;Horizontal cells: 33.7" "Low cancer specificity" "Detected in some" "Region enhanced" "Detected in many" "basal ganglia: 21.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "RT4: 26.4" "Region enriched" "Detected in many" 9 "basal ganglia: 164.4" "Region enriched" "Detected in many" 13 "basal ganglia: 86.7" "HPA013393, HPA017304" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Cytosol "HPA013393: AB_1847833, HPA017304: " "unprognostic (2.74e-2)" "unprognostic (6.36e-3)" "unprognostic (2.02e-1)" "unprognostic (1.07e-1)" "unprognostic (7.63e-3)" "unprognostic (1.28e-1)" "unprognostic (1.15e-6)" "unprognostic (6.69e-2)" "unprognostic (1.05e-1)" "unprognostic (1.24e-1)" "unprognostic (1.49e-1)" "unprognostic (2.74e-2)" "unprognostic (8.60e-4)" "unprognostic (5.86e-2)" "unprognostic (5.43e-1)" "unprognostic (6.00e-3)" "unprognostic (1.10e-2)" 0.4 0.6 4.7 0.0 21.3 0.0 0.2 0.0 8.5 0.4 0.1 0.2 0.1 0.1 0.2 0.3 0.2 0.4 0.0 3.1 0.4 0.7 1.1 0.7 0.0 0.3 0.9 0.1 0.0 0.0 0.1 1.1 0.0 1.1 0.3 8.4 0.0 0.4 0.0 0.0 0.3 0.1 0.7 0.1 0.2 0.0 1.8 0.3 0.1 0.6 0.1 0.7 0.4 2.9 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 26.4 0.7 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.7 21.3 0.0 8.5 3.1 0.4 0.3 0.9 0.0 0.7 1.8 2.9 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 40.1 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.4 0.4 0.0 33.7 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 3.0 0.0 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 DRD4 ENSG00000069696 "Dopamine receptor D4" P21917 11 637269-640706 "FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "Biological rhythms" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 5 "Bipolar cells: 168.8;Cone photoreceptor cells: 87.6;Rod photoreceptor cells: 206.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 3.9" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA062682 Uncertain "Plasma membrane,Centrosome" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 71: Testis - DNA repair" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Centrosome "HPA062682: " "unprognostic (8.83e-2)" "unprognostic (2.99e-2)" "unprognostic (4.98e-4)" "unprognostic (3.81e-2)" "unprognostic (7.52e-2)" "unprognostic (7.89e-3)" "unprognostic (3.14e-2)" "unprognostic (2.96e-1)" "unprognostic (8.45e-2)" "unprognostic (5.07e-2)" "unprognostic (3.28e-1)" "unprognostic (8.59e-2)" "unprognostic (1.05e-4)" "unprognostic (1.26e-2)" "unprognostic (8.21e-2)" "unprognostic (2.36e-2)" "unprognostic (1.85e-1)" 0.9 0.8 0.5 0.0 0.6 0.0 0.8 1.3 0.6 2.5 0.1 1.9 0.0 1.6 0.0 1.1 2.5 0.0 1.1 0.4 0.0 1.3 1.5 1.3 0.0 0.6 0.2 3.5 1.5 0.0 4.2 0.0 0.5 2.3 0.0 0.0 0.5 0.0 1.0 1.5 1.1 0.0 0.1 0.6 0.8 2.5 0.3 0.0 1.8 0.0 0.0 1.7 1.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.5 0.6 1.3 0.6 0.4 0.0 0.6 0.2 0.5 0.1 0.3 0.6 0.5 0.0 0.5 4.2 0.2 0.0 0.3 0.2 0.0 168.8 0.3 0.4 1.7 0.0 0.1 1.8 87.6 0.6 8.6 0.8 0.0 0.1 0.7 0.3 0.4 1.5 0.0 0.0 0.8 0.4 0.3 0.5 2.0 0.7 0.0 1.5 0.0 0.1 0.2 6.7 1.2 1.3 0.0 0.3 0.3 0.2 0.6 0.9 0.0 0.0 0.1 26.0 0.0 0.0 2.6 0.4 0.2 0.7 0.1 1.1 8.3 1.9 0.1 206.9 0.0 0.8 0.6 1.2 2.6 0.8 0.4 0.1 0.1 0.5 1.3 0.3 DRP2 ENSG00000102385 "Dystrophin related protein 2" Q13474 X 101219769-101264502 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.8;lymphoid tissue: 4.7" "Group enriched" "Detected in some" 6 "Excitatory neurons: 35.6;Inhibitory neurons: 24.5;Oligodendrocyte precursor cells: 11.1" "Cancer enhanced" "Detected in single" "glioma: 1.4" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "RH-30: 10.7;TIME: 18.5;U-87 MG: 4.4" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 56.0" HPA002949 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles, Plasma membrane" "HPA002949: AB_1078706" "unprognostic (8.47e-4)" "unprognostic (3.56e-3)" "unprognostic (1.01e-2)" "unprognostic (5.58e-4)" "unprognostic (1.74e-2)" "unprognostic (2.47e-2)" "unprognostic (7.93e-3)" "unprognostic (2.94e-3)" "unprognostic (1.27e-2)" "unprognostic (5.46e-3)" "unprognostic (1.42e-1)" "unprognostic (4.61e-2)" "unprognostic (4.44e-16)" "unprognostic (3.71e-4)" "unprognostic (4.22e-1)" "unprognostic (9.03e-2)" "unprognostic (1.25e-1)" 0.7 0.3 4.0 0.2 5.9 0.2 0.4 0.0 8.8 0.6 0.0 3.2 0.2 0.7 0.7 0.2 0.2 0.2 0.2 6.2 0.7 0.0 0.0 0.0 0.0 0.1 2.6 1.4 0.0 0.0 2.3 0.0 0.6 1.3 0.4 1.0 0.6 0.9 0.2 0.3 0.8 0.6 0.0 0.0 0.3 0.5 0.7 4.7 0.0 1.1 0.0 0.6 1.1 4.8 0.0 0.6 2.2 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.9 0.0 0.4 0.3 0.2 0.1 0.6 0.0 0.3 0.0 0.7 0.1 0.2 0.2 0.6 0.0 0.2 0.1 0.4 1.4 0.0 0.7 0.0 0.0 1.4 0.5 0.0 0.9 1.5 0.0 1.3 0.5 0.1 0.1 0.1 0.3 10.7 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.4 0.0 0.1 18.5 0.2 0.7 0.2 0.4 0.0 0.1 0.0 4.4 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.9 0.0 8.8 6.2 0.7 0.1 2.6 0.6 0.0 0.7 4.8 0.0 0.0 0.0 2.3 0.0 0.1 0.0 0.0 0.0 3.7 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 1.8 0.0 35.6 0.0 0.1 0.6 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 24.5 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 1.0 0.0 0.3 0.0 11.1 1.4 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 DSC2 "CDHF2, DSC3" ENSG00000134755 "Desmocollin 2" Q02487 18 31058840-31102522 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 164.0;vagina: 97.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 384.0;Paneth cells: 324.8;Squamous epithelial cells: 705.6" "Cancer enhanced" "Detected in many" "head and neck cancer: 48.7" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 9 "eosinophil: 28.9;neutrophil: 8.1" "Lineage enriched" "Detected in many" 14 "granulocytes: 28.9" "Cell line enhanced" "Detected in many" "BEWO: 37.6;CAPAN-2: 48.3;HaCaT: 71.1;hTCEpi: 76.0;OE19: 60.7;SK-BR-3: 44.4;SuSa: 43.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA011911, HPA012615" Enhanced Supported "Plasma membrane,Cytosol" NA NA 24000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane" Cytosol "HPA011911: AB_1847618, HPA012615: AB_1847619" "unprognostic (3.28e-2)" "unprognostic (3.20e-1)" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (1.90e-1)" "unprognostic (3.04e-2)" "unprognostic (1.30e-2)" "prognostic unfavorable (5.80e-4)" "unprognostic (7.66e-2)" "unprognostic (4.07e-2)" "unprognostic (1.22e-3)" "unprognostic (2.10e-1)" "unprognostic (1.43e-3)" "unprognostic (1.60e-1)" "unprognostic (1.75e-1)" "unprognostic (2.49e-1)" "prognostic unfavorable (3.01e-4)" 5.5 1.8 1.3 12.7 1.4 0.7 22.2 1.3 1.6 59.2 1.9 50.5 41.6 1.5 5.9 164.0 6.1 3.7 10.6 1.2 2.0 5.9 7.3 7.9 3.7 2.6 1.5 0.6 10.5 27.0 0.5 21.3 2.2 15.8 44.5 1.0 46.8 1.0 0.3 11.9 42.9 4.0 1.8 3.0 43.2 0.8 1.6 6.6 4.0 3.1 62.2 3.6 97.4 2.3 18.1 1.9 2.9 0.0 0.0 0.0 37.6 0.0 0.0 0.0 0.0 9.8 48.3 0.0 0.7 0.0 0.9 71.1 11.8 4.9 0.0 0.0 6.9 27.1 8.4 16.9 0.3 0.2 0.5 0.4 76.0 0.0 7.3 6.1 0.0 0.0 13.4 0.0 0.0 14.7 0.0 1.1 11.3 60.7 17.4 13.2 0.0 0.2 0.1 0.7 0.0 0.1 0.0 44.4 0.0 43.4 12.2 18.1 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 28.9 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.1 0.0 0.1 0.0 0.0 0.4 1.3 1.4 1.3 1.6 1.2 2.0 2.6 1.5 2.2 1.8 1.6 2.3 25.1 28.9 5.6 3.3 1.0 83.7 44.5 16.4 67.7 0.8 75.3 65.7 33.8 32.9 11.1 7.3 0.0 100.8 1.0 384.0 0.0 83.5 0.1 19.1 4.0 6.7 69.4 0.4 3.3 33.2 186.6 5.9 47.4 43.8 0.0 2.7 8.2 16.0 24.8 0.0 1.5 83.1 20.3 48.8 29.3 0.2 0.3 35.3 14.2 4.7 25.2 11.2 0.0 2.0 0.2 155.7 324.8 0.7 0.3 140.6 118.2 9.7 3.8 0.7 0.0 1.2 3.0 0.1 1.3 705.6 55.0 83.9 2.0 0.3 114.0 76.1 DSC3 "CDHF3, DSC, DSC1, DSC2, DSC4" ENSG00000134762 "Desmocollin 3" Q14574 18 30989365-31042815 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Cell adhesion" Hypotrichosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 99.2;skin 1: 372.6" "Group enriched" "Detected in many" 5 "Basal keratinocytes: 500.7;Basal squamous epithelial cells: 214.5;Squamous epithelial cells: 419.6;Suprabasal keratinocytes: 688.8" "Cancer enhanced" "Detected in many" "cervical cancer: 78.6;head and neck cancer: 107.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 246.2;HBEC3-KT: 54.6;hTCEpi: 156.7;hTERT-HME1: 103.6;REH: 44.8" "Region enhanced" "Detected in some" "hippocampal formation: 3.3" "CAB037328, HPA049265, HPA073937" Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 6000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cell Junctions" "CAB037328: , HPA049265: AB_2680695, HPA073937: AB_2686645" "unprognostic (4.44e-3)" "unprognostic (6.28e-2)" "unprognostic (1.46e-1)" "unprognostic (3.02e-3)" "unprognostic (2.38e-1)" "unprognostic (1.32e-2)" "unprognostic (6.38e-2)" "unprognostic (1.84e-2)" "unprognostic (2.41e-1)" "unprognostic (3.48e-2)" "unprognostic (3.92e-3)" "unprognostic (3.13e-1)" "unprognostic (4.13e-4)" "unprognostic (1.22e-2)" "unprognostic (7.85e-2)" "unprognostic (3.47e-1)" "prognostic unfavorable (1.04e-5)" 4.8 0.1 0.1 0.5 0.0 0.2 12.5 0.1 0.0 23.8 0.0 0.3 0.4 0.1 1.2 99.2 1.3 0.0 0.4 0.1 0.0 0.0 0.1 0.3 0.4 0.0 0.0 0.4 0.2 3.4 0.2 12.5 0.0 6.0 0.1 0.1 19.6 1.3 1.0 372.6 0.3 0.5 0.0 0.0 0.1 0.1 0.0 7.7 0.1 0.0 24.7 3.5 48.5 0.0 17.2 1.8 0.2 0.0 0.1 0.0 6.6 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.1 0.0 0.0 246.2 0.0 54.6 0.0 0.1 14.6 0.9 4.7 0.4 9.7 0.1 0.2 10.2 156.7 0.0 103.6 19.6 0.0 0.0 0.4 0.4 0.0 0.0 0.0 0.1 0.9 0.1 21.8 44.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.2 1.1 0.3 0.0 500.7 62.0 49.5 214.5 0.0 3.1 8.0 1.3 0.0 30.3 0.0 0.0 73.5 0.0 0.0 0.0 0.1 0.0 0.1 0.0 3.3 2.4 0.0 0.3 0.0 14.2 4.6 0.0 0.1 0.0 0.1 0.0 0.0 5.3 0.0 0.3 0.2 12.2 0.0 34.8 0.0 0.0 0.6 39.2 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 1.2 32.1 0.0 0.1 10.2 0.0 0.0 0.0 3.4 0.1 0.1 419.6 688.8 25.0 2.3 0.0 0.1 89.1 DSEL "C18orf4, DE-epi2, FLJ11477, NCAG1" ENSG00000171451 "Dermatan sulfate epimerase like" Q8IZU8 18 67506587-67516720 "Predicted membrane proteins" Isomerase "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 11.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 86.4;Extravillous trophoblasts: 72.5;Oligodendrocyte precursor cells: 112.6;Oligodendrocytes: 104.2;Theca cells: 83.9" "Cancer enhanced" "Detected in many" "glioma: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.7;BJ hTERT+: 43.0;fHDF/TERT166: 38.9;LHCN-M2: 92.1;U-138 MG: 95.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA060942 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA060942: AB_2684392" "unprognostic (2.49e-1)" "unprognostic (5.00e-1)" "unprognostic (1.67e-1)" "unprognostic (1.19e-5)" "unprognostic (1.56e-1)" "unprognostic (2.71e-1)" "unprognostic (2.40e-3)" "unprognostic (7.11e-2)" "unprognostic (4.91e-1)" "unprognostic (2.83e-1)" "unprognostic (2.19e-2)" "unprognostic (2.47e-1)" "unprognostic (7.95e-3)" "unprognostic (3.25e-2)" "unprognostic (1.24e-1)" "unprognostic (9.70e-3)" "unprognostic (1.16e-4)" 4.0 1.3 5.1 1.3 8.5 0.3 2.6 7.3 4.7 5.1 0.7 2.2 0.6 2.6 1.6 1.1 3.3 4.0 2.2 5.1 6.4 4.3 3.5 2.7 0.5 9.5 7.4 3.6 1.5 3.2 0.3 6.1 8.8 2.0 1.3 0.8 0.8 2.1 0.7 1.2 1.1 3.6 5.9 2.0 1.2 1.3 7.0 0.8 1.0 1.8 0.3 1.7 1.4 11.7 0.0 0.3 8.7 0.1 16.5 24.3 0.9 70.7 43.0 19.2 8.3 0.1 0.2 0.0 0.1 38.9 4.7 0.4 1.7 3.5 18.5 0.0 0.1 0.0 8.5 0.1 14.6 0.0 0.1 25.3 5.1 11.7 26.0 6.8 3.8 0.0 0.0 1.1 92.1 0.0 0.0 0.0 1.3 0.0 3.7 0.8 19.3 0.1 8.7 0.1 3.1 4.0 4.8 0.2 0.0 3.7 0.1 0.0 6.2 95.6 2.4 6.2 8.6 0.3 0.0 0.0 20.0 0.0 8.1 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 5.1 8.5 7.3 4.7 5.1 6.4 9.5 7.4 8.8 5.9 7.0 11.7 15.9 6.4 16.2 3.3 2.6 11.6 9.9 8.6 19.4 10.1 14.5 12.3 13.3 47.1 5.2 11.0 4.2 2.8 1.4 1.0 0.0 9.7 1.8 3.9 86.4 10.9 6.6 0.0 10.3 2.3 72.5 44.3 8.2 4.2 4.5 9.5 13.2 15.6 2.6 3.3 25.5 1.1 0.0 2.2 9.3 1.7 24.5 3.5 7.2 2.8 0.0 12.6 1.0 112.6 104.2 6.6 0.1 36.9 0.3 8.5 0.4 26.4 1.3 4.2 13.1 43.3 20.9 31.6 21.9 7.1 13.2 8.9 4.9 83.9 0.7 5.2 DUSP15 "bA243J16.5, bA243J16.6, C20orf57, FLJ20645, VHY" ENSG00000149599 "Dual specificity phosphatase 15" Q9H1R2 20 31847637-31870747 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "testis: 210.5" "Group enriched" "Detected in many" 4 "Distal tubular cells: 273.9;Early spermatids: 288.8;Late spermatids: 979.4" "Cancer enhanced" "Detected in many" "renal cancer: 6.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 4.8;REH: 16.0;SH-SY5Y: 4.3;SK-MEL-30: 4.0;U-2 OS: 3.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076649 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: Testis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA076649: AB_2686811" "unprognostic (3.84e-2)" "unprognostic (2.30e-1)" "unprognostic (2.28e-1)" "unprognostic (9.01e-3)" "unprognostic (3.88e-2)" "unprognostic (2.36e-1)" "unprognostic (1.47e-2)" "unprognostic (2.24e-2)" "unprognostic (1.43e-1)" "unprognostic (1.76e-1)" "unprognostic (1.48e-5)" "unprognostic (7.31e-2)" "prognostic favorable (5.40e-7)" "unprognostic (2.79e-2)" "unprognostic (1.93e-1)" "unprognostic (3.11e-3)" "unprognostic (2.55e-1)" 1.7 5.9 5.3 0.2 7.6 0.1 3.4 10.7 7.5 5.9 4.9 1.8 0.5 3.4 9.0 1.0 1.5 0.7 7.8 4.8 7.7 50.0 0.7 1.6 0.6 17.1 8.7 5.2 2.4 13.0 8.7 0.7 8.1 6.6 0.1 0.6 2.1 3.0 0.9 1.2 1.5 0.3 7.8 2.7 2.3 210.5 7.6 0.3 9.6 0.3 0.2 2.5 2.7 8.8 0.2 0.2 0.1 1.4 0.0 0.3 0.0 0.0 0.0 0.7 0.0 4.8 0.1 1.0 1.9 0.2 2.6 0.0 0.3 0.0 0.0 0.0 0.5 0.4 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.3 0.0 3.4 0.6 0.0 0.0 16.0 1.8 0.1 0.0 0.0 2.1 4.3 2.6 0.0 4.0 0.1 1.1 0.9 0.0 0.0 3.6 0.0 0.0 1.6 0.0 0.0 0.0 0.6 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.3 7.6 10.7 7.5 4.8 7.7 17.1 8.7 8.1 7.8 7.6 8.8 2.9 0.0 0.0 1.3 0.8 0.6 1.3 0.0 0.0 0.6 3.6 4.4 2.5 1.5 0.0 18.4 4.2 0.0 0.4 0.1 273.9 2.4 288.8 0.6 4.0 2.2 1.8 0.0 1.7 1.0 0.1 2.9 1.5 0.6 0.0 7.0 1.8 0.1 0.6 6.7 2.6 0.4 0.0 0.6 1.9 979.4 8.7 1.2 7.2 0.0 0.6 2.9 0.0 3.0 4.7 0.6 0.0 10.9 0.0 0.9 0.0 55.3 0.1 0.3 0.0 2.5 3.3 121.5 6.0 0.3 0.1 0.1 0.3 7.5 0.7 0.4 DYSF "FER1L1, LGMD2B" ENSG00000135636 Dysferlin O75923 2 71453722-71686768 "Disease related genes, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "Disease variant, Limb-girdle muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 95.3" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Endothelial cells: 43.7;Excitatory neurons: 34.7;Hepatic stellate cells: 32.2;Kupffer cells: 27.1;Oligodendrocytes: 62.7;Syncytiotrophoblasts: 66.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 7 "neutrophil: 27.0" "Lineage enriched" "Detected in many" 7 "granulocytes: 27.0" "Group enriched" "Detected in many" 5 "hTERT-RPE1: 31.9;HUVEC TERT2: 85.5;LHCN-M2: 75.3;RH-30: 78.5;TIME: 58.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB002510, HPA017071, HPA021945" Enhanced Supported "Plasma membrane,Centriolar satellite" Yes No "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Centriolar satellite" "CAB002510: AB_442097, HPA017071: AB_1847927, HPA021945: AB_1847928" "unprognostic (1.04e-1)" "unprognostic (7.66e-3)" "unprognostic (5.43e-3)" "unprognostic (1.66e-2)" "unprognostic (1.65e-1)" "unprognostic (2.42e-1)" "unprognostic (4.43e-2)" "unprognostic (1.14e-1)" "unprognostic (2.70e-1)" "unprognostic (3.21e-1)" "unprognostic (2.93e-1)" "unprognostic (6.43e-2)" "unprognostic (4.88e-3)" "unprognostic (1.22e-2)" "unprognostic (3.18e-2)" "unprognostic (1.36e-1)" "unprognostic (5.97e-3)" 10.1 1.7 1.0 11.5 1.1 31.6 4.3 4.1 7.7 1.9 0.7 7.0 2.0 2.3 0.5 7.4 3.2 4.6 16.8 0.2 3.8 3.6 6.5 8.3 3.7 14.8 5.1 1.3 1.5 2.3 1.5 21.1 13.7 3.3 2.5 0.5 1.3 4.8 95.3 1.2 3.1 10.2 2.0 21.4 2.5 1.1 10.2 2.3 4.6 32.3 0.9 6.9 1.8 1.8 1.1 0.0 3.3 3.0 0.0 0.0 6.1 0.1 0.8 2.2 1.5 0.4 1.0 0.0 12.1 0.1 3.4 2.5 0.0 1.2 1.1 0.0 0.0 0.2 0.2 0.0 0.3 0.1 0.0 1.5 0.0 2.3 10.6 31.9 85.5 0.2 8.4 0.0 75.3 0.0 0.0 5.8 8.1 0.0 0.9 0.0 78.5 0.0 2.6 0.2 0.0 0.0 4.1 0.7 0.1 7.9 0.3 0.8 58.1 0.3 3.8 0.2 1.1 0.0 0.0 0.0 0.0 13.3 0.0 0.0 4.1 0.1 0.5 0.7 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 27.0 0.4 0.1 0.0 0.0 1.4 1.0 1.1 4.1 7.7 0.2 3.8 14.8 5.1 13.7 2.0 10.2 1.8 30.5 3.2 8.1 1.0 1.0 2.4 0.0 0.1 0.0 1.1 0.3 0.6 24.0 0.0 1.3 0.0 0.0 8.1 0.7 0.1 0.0 0.4 4.8 0.7 1.3 43.7 0.0 2.7 34.7 0.2 3.8 2.2 0.0 9.3 2.5 0.3 32.2 13.4 11.4 0.0 13.0 0.2 0.0 27.1 3.0 6.0 0.6 10.2 0.0 16.9 5.8 0.1 0.0 2.5 62.7 0.1 0.0 0.7 0.1 0.2 0.0 2.1 0.7 0.2 6.6 5.2 5.5 0.6 1.1 0.1 1.6 66.2 1.1 0.9 0.0 0.1 EDNRA "ET-A, ETA-R, hET-AR" ENSG00000151617 "Endothelin receptor type A" P25101 4 147480917-147544954 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "seminal vesicle: 113.9" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 117.1;Leydig cells: 43.8;Peritubular cells: 68.1;Sertoli cells: 52.6;Smooth muscle cells: 108.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 9.4;ASC TERT1: 18.2;HHSteC: 9.3;LHCN-M2: 22.7;SH-SY5Y: 16.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA013774, CAB018957" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB018957: AB_2039838, HPA013774: AB_1847994" "unprognostic (3.08e-2)" "unprognostic (6.28e-2)" "unprognostic (1.78e-1)" "unprognostic (3.42e-1)" "unprognostic (1.07e-2)" "unprognostic (1.39e-1)" "unprognostic (3.20e-2)" "unprognostic (7.20e-2)" "unprognostic (2.75e-3)" "unprognostic (1.47e-2)" "unprognostic (1.34e-3)" "unprognostic (2.88e-1)" "prognostic unfavorable (1.50e-7)" "prognostic unfavorable (3.93e-4)" "unprognostic (6.20e-3)" "unprognostic (3.11e-2)" "unprognostic (2.53e-3)" 14.0 5.5 2.1 3.3 2.8 0.0 8.3 2.7 4.2 57.0 2.1 3.2 3.4 44.7 23.3 4.4 18.4 12.7 26.0 2.2 2.2 4.2 3.1 22.7 3.8 2.9 3.1 37.5 1.1 3.4 2.8 12.1 2.9 30.7 3.4 0.3 6.4 113.9 4.0 4.6 2.9 45.1 2.5 8.4 5.4 6.2 2.9 4.9 6.8 5.5 2.6 11.8 24.0 3.0 0.0 1.2 5.2 0.0 9.4 18.2 0.0 2.9 3.8 0.4 0.1 0.2 0.0 0.0 0.0 0.9 0.6 0.0 0.4 0.7 0.2 0.0 1.9 0.0 2.8 0.0 9.3 0.0 0.0 6.9 0.6 0.5 0.0 3.4 0.0 0.0 0.0 1.4 22.7 0.3 0.0 0.1 1.5 0.0 1.1 0.0 0.9 0.1 1.3 1.0 0.0 16.3 0.0 0.0 0.0 3.4 0.0 0.0 0.0 3.6 0.7 0.0 0.0 1.3 0.4 0.0 7.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 2.8 2.7 4.2 2.2 2.2 2.9 3.1 2.9 2.5 2.9 3.0 7.7 3.2 5.3 1.0 0.0 3.1 0.8 1.7 27.3 0.1 0.8 5.2 24.9 0.0 4.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 2.9 3.4 117.1 8.0 0.0 0.0 5.3 0.0 0.1 15.9 0.0 2.7 0.0 14.3 0.0 0.0 0.6 0.0 22.5 0.0 0.0 0.0 3.9 3.5 43.8 0.8 3.6 9.4 0.0 0.1 0.0 2.0 1.0 0.2 0.0 68.1 0.0 1.4 0.0 0.5 0.0 0.5 52.6 0.6 108.6 0.7 0.7 7.1 2.7 0.1 0.9 0.3 0.0 0.4 EDNRB "ETB, HSCR, HSCR2" ENSG00000136160 "Endothelin receptor type B" P24530 13 77895481-77975529 "Disease related genes, FDA approved drug targets, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Albinism, Deafness, Disease variant, FDA approved drug targets, Hirschsprung disease, Waardenburg syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 127.8" "Cell type enhanced" "Detected in many" "Adipocytes: 120.5;Astrocytes: 126.3;Hepatic stellate cells: 112.5;Melanocytes: 110.3;Muller glia cells: 116.2;Sertoli cells: 216.9;Skeletal myocytes: 81.3;Smooth muscle cells: 102.1" "Cancer enhanced" "Detected in all" "melanoma: 127.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 68.0;ASC diff: 50.5;SK-MEL-30: 66.0;U-266/70: 40.7;WM-115: 131.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017842, HPA027546" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 17: WM-115 - Nervous system development" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "CAB017842: , HPA027546: AB_2672327" "unprognostic (7.75e-2)" "unprognostic (6.73e-2)" "unprognostic (1.41e-3)" "unprognostic (2.59e-2)" "unprognostic (8.37e-2)" "unprognostic (2.45e-3)" "unprognostic (4.17e-3)" "unprognostic (5.43e-2)" "unprognostic (1.02e-1)" "unprognostic (1.38e-2)" "unprognostic (3.40e-2)" "unprognostic (3.01e-2)" "prognostic favorable (7.20e-5)" "unprognostic (1.59e-2)" "unprognostic (3.86e-2)" "unprognostic (4.58e-2)" "unprognostic (6.77e-3)" 58.8 41.2 34.7 19.5 50.8 0.9 39.8 44.6 26.1 18.7 6.7 13.0 20.0 13.1 3.7 8.2 14.1 14.9 28.1 27.5 51.6 33.0 50.9 51.2 10.4 76.2 66.0 4.7 11.4 15.3 9.6 127.8 47.9 25.3 13.2 17.9 27.0 6.9 11.3 12.5 21.9 12.9 97.2 16.8 10.6 2.3 64.9 4.0 31.8 18.8 4.7 23.6 15.5 78.7 5.7 0.0 68.0 0.0 50.5 2.0 1.0 0.0 0.1 0.0 0.0 25.9 0.0 0.0 2.6 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.3 0.3 0.0 0.0 3.5 0.0 0.2 13.2 0.0 0.0 0.0 0.1 0.6 0.0 0.2 0.2 1.7 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.1 0.7 0.1 0.1 0.5 0.1 0.0 66.0 8.9 0.0 0.3 0.3 0.6 0.1 0.0 0.4 40.7 24.9 0.1 1.2 0.0 131.8 0.0 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 34.7 50.8 44.6 26.1 27.5 51.6 76.2 66.0 47.9 97.2 64.9 78.7 120.5 12.8 51.0 126.3 0.2 14.8 1.0 0.0 1.2 5.8 1.2 2.8 10.8 0.0 2.5 0.0 6.2 14.7 0.3 0.1 0.0 0.0 2.9 2.9 20.7 73.3 0.0 0.0 1.3 0.0 13.9 51.1 1.1 35.9 6.3 2.1 112.5 1.1 13.4 0.0 1.6 0.0 0.0 18.7 10.6 2.2 79.9 5.2 110.3 6.5 0.1 116.2 0.0 48.2 0.9 0.1 0.0 2.6 0.1 2.6 0.0 0.1 1.5 4.4 216.9 81.3 102.1 0.4 2.1 0.2 7.2 5.7 1.6 2.5 0.0 1.5 EEF1AKMT1 N6AMT2 ENSG00000150456 "EEF1A lysine methyltransferase 1" Q8WVE0 13 20728731-20773961 "Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 22.4;Breast myoepithelial cells: 19.9;Cytotrophoblasts: 19.8;Distal tubular cells: 27.4;Endometrial ciliated cells: 20.9;Proximal tubular cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA040417, HPA042543" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 32: U-937 - Innate immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA040417: AB_2676973, HPA042543: AB_2678045" "unprognostic (4.14e-1)" "unprognostic (5.11e-2)" "unprognostic (8.57e-2)" "prognostic favorable (1.82e-4)" "unprognostic (9.14e-2)" "unprognostic (3.44e-1)" "unprognostic (2.24e-1)" "unprognostic (1.65e-1)" "unprognostic (1.11e-1)" "unprognostic (1.41e-1)" "unprognostic (1.51e-2)" "unprognostic (1.39e-1)" "unprognostic (2.39e-3)" "unprognostic (3.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.81e-2)" "unprognostic (4.31e-2)" 9.6 10.3 11.1 5.3 11.6 3.4 9.8 11.8 16.8 11.2 10.5 9.5 4.5 10.8 14.3 5.8 11.1 6.3 9.9 11.2 12.6 9.5 13.5 6.4 6.8 11.1 11.6 10.4 6.3 9.5 9.9 6.5 11.8 10.2 6.0 10.2 7.9 8.9 11.1 5.9 5.6 9.2 12.0 5.8 7.1 4.3 12.0 9.2 9.5 12.2 6.8 8.8 7.5 12.3 11.1 8.5 6.9 11.4 28.3 29.2 16.9 14.4 11.0 12.4 6.4 11.9 12.1 18.0 10.5 15.8 5.8 9.0 9.4 12.2 12.8 11.7 8.4 23.3 3.8 22.8 15.6 46.3 4.6 20.1 10.7 9.2 20.4 13.8 22.4 15.7 13.6 2.4 35.5 30.7 15.6 41.0 12.0 20.2 6.2 19.2 7.6 3.5 17.8 12.7 15.8 9.4 12.5 6.1 16.5 5.9 6.4 42.4 13.3 8.5 0.0 19.1 6.4 3.3 6.7 19.9 7.3 31.4 6.1 0.0 5.2 0.9 8.6 4.1 9.6 13.1 10.3 9.0 8.9 5.4 13.0 11.3 0.7 16.3 4.4 10.8 12.0 6.7 11.1 11.6 11.8 16.8 11.2 12.6 11.1 11.6 11.8 12.0 12.0 12.3 15.0 22.4 9.2 0.0 0.9 0.0 0.0 0.0 0.0 0.0 13.3 19.9 0.0 0.0 8.1 7.3 0.0 19.8 3.1 0.0 27.4 12.6 0.0 20.9 16.2 6.0 0.0 0.0 0.0 10.4 15.2 8.9 0.0 7.0 3.8 13.2 0.0 0.0 18.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.5 0.0 0.0 0.4 0.0 0.0 36.5 7.3 0.0 0.0 0.0 7.3 0.0 0.0 0.0 0.0 15.7 2.2 9.9 0.0 0.0 EEF2 "EEF-2, EF2" ENSG00000167658 "Eukaryotic translation elongation factor 2" P13639 19 3976056-3985463 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Elongation factor" "Cancer-related genes, Disease variant, FDA approved drug targets, Neurodegeneration, Spinocerebellar ataxia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007795, HPA040534, HPA057351" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 17000000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB007795: AB_598149, HPA040534: AB_2677024, HPA057351: AB_2683417" "unprognostic (5.47e-2)" "unprognostic (9.59e-2)" "unprognostic (3.75e-1)" "prognostic favorable (1.81e-6)" "unprognostic (2.06e-2)" "unprognostic (3.26e-1)" "unprognostic (1.53e-2)" "unprognostic (2.11e-1)" "unprognostic (1.83e-1)" "unprognostic (1.77e-2)" "unprognostic (1.25e-2)" "unprognostic (1.42e-1)" "prognostic favorable (1.25e-5)" "unprognostic (4.46e-2)" "unprognostic (5.60e-2)" "unprognostic (6.82e-2)" "unprognostic (9.86e-2)" 1022.6 1037.0 771.8 507.3 755.2 920.3 946.7 737.2 1059.6 966.7 807.6 1122.4 821.4 887.6 563.7 1062.3 857.3 501.2 1396.6 740.9 729.1 843.2 1152.9 666.9 685.4 775.4 769.6 1627.6 3194.1 494.0 838.0 386.2 782.3 819.2 344.5 224.7 1276.4 500.3 2322.6 1142.7 798.9 385.4 758.3 721.6 1266.6 490.5 762.7 541.0 793.6 1112.4 499.0 927.8 797.7 745.1 1456.8 1018.4 579.3 1539.4 1515.6 2706.7 830.9 1110.4 1479.8 1036.7 1012.7 1618.1 652.7 3000.6 644.1 1032.3 461.1 1069.8 919.4 1719.4 544.2 755.0 1533.0 768.5 919.9 1677.0 2204.8 1668.0 1277.6 3515.5 1777.2 916.0 1404.1 1497.5 1086.6 1434.4 1526.7 2145.4 642.1 2095.7 1510.1 1266.3 1537.0 518.3 1015.7 1654.2 860.3 1938.3 871.2 1270.2 1575.4 1466.4 699.0 1377.1 2058.3 543.1 1344.7 1992.7 1321.8 738.2 765.7 1521.4 1738.7 2276.4 1644.3 1485.3 1100.4 2065.8 986.6 81.2 455.7 64.1 259.8 333.1 460.2 578.5 453.0 344.6 430.7 478.1 497.2 404.1 43.1 355.3 342.1 358.7 429.4 756.5 771.8 755.2 737.2 1059.6 740.9 729.1 775.4 769.6 782.3 758.3 762.7 745.1 323.1 221.2 392.2 24.5 1125.5 1321.1 1071.3 754.3 1269.7 212.6 981.3 694.3 627.9 597.7 448.3 255.6 77.2 958.1 535.9 556.9 986.1 716.0 799.2 318.2 675.4 568.2 744.2 934.8 23.2 1816.8 1305.0 679.7 619.3 428.5 373.4 596.1 656.8 690.6 610.1 203.6 28.9 982.1 411.0 885.4 859.5 1195.6 1008.4 514.2 645.7 36.5 907.5 429.1 614.8 27.2 42.2 868.2 815.5 832.8 992.8 1010.5 1562.7 1078.8 194.5 134.1 585.1 797.7 697.3 371.5 308.4 1343.0 1347.1 1243.1 727.1 1044.3 1168.4 1051.6 EFCAB1 FLJ11767 ENSG00000034239 "EF-hand calcium binding domain 1" Q9HAE3 8 48710789-48735311 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "fallopian tube: 91.6;testis: 37.5" "Group enriched" "Detected in many" 19 "Early spermatids: 538.8;Endometrial ciliated cells: 159.1;Late spermatids: 552.0;Respiratory ciliated cells: 310.7" "Cancer enhanced" "Detected in some" "endometrial cancer: 2.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "neutrophil: 1.2" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "A-431: 6.5;ASC diff: 2.6;ASC TERT1: 6.2;CAPAN-2: 3.1;hTEC/SVTERT24-B: 2.6;SCLC-21H: 4.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA023527, HPA069955" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 34: Spermatids - Unknown function" Nucleoplasm "Plasma membrane" "HPA023527: AB_2231065, HPA069955: AB_2686220" "unprognostic (5.29e-3)" "unprognostic (7.39e-3)" "unprognostic (1.05e-1)" "unprognostic (2.67e-3)" "unprognostic (4.67e-2)" "unprognostic (2.77e-1)" "unprognostic (9.81e-2)" "unprognostic (1.62e-1)" "unprognostic (2.52e-2)" "unprognostic (1.85e-1)" "unprognostic (5.94e-3)" "unprognostic (7.81e-2)" "unprognostic (4.87e-3)" "unprognostic (4.81e-2)" "unprognostic (1.99e-1)" "unprognostic (2.51e-1)" "unprognostic (3.47e-3)" 0.3 1.5 3.1 0.1 4.7 0.7 3.0 1.9 2.5 11.4 22.4 0.5 0.6 12.4 2.5 0.7 91.6 0.6 0.2 3.7 4.9 0.5 0.7 10.6 0.1 13.5 12.1 19.3 3.2 0.0 3.1 0.5 7.0 5.4 0.4 0.0 2.0 5.9 0.0 4.7 1.0 2.9 9.1 0.3 0.6 37.5 5.7 0.4 0.1 0.2 0.2 2.3 3.4 8.5 6.5 0.0 0.8 0.0 2.6 6.2 0.0 0.1 0.6 0.0 0.2 0.0 3.1 0.0 0.0 0.1 0.0 1.7 0.0 0.8 0.2 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 2.1 0.2 2.6 1.1 0.6 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 1.5 4.9 0.3 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.2 0.2 0.2 0.0 0.2 0.1 0.0 1.2 0.3 0.0 0.0 0.1 0.0 3.1 4.7 1.9 2.5 3.7 4.9 13.5 12.1 7.0 9.1 5.7 8.5 0.4 0.0 5.9 0.0 0.0 6.8 9.7 14.7 4.0 0.0 0.4 9.1 0.4 0.0 20.4 0.0 0.0 0.3 0.0 0.0 0.0 0.3 538.8 159.1 4.7 1.2 0.0 0.0 0.7 1.5 0.1 2.2 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 10.2 0.0 0.3 552.0 4.7 0.8 1.8 0.0 0.0 0.0 0.0 0.5 0.0 1.3 0.0 5.7 0.0 3.4 0.0 0.3 310.7 0.0 0.0 0.7 6.2 16.9 4.5 0.1 1.8 0.3 0.4 3.9 0.0 2.5 EFCAB2 "CFAP200, DRC8, MGC12458" ENSG00000203666 "EF-hand calcium binding domain 2" Q5VUJ9 1 244969705-245127164 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 112.3;Endometrial ciliated cells: 103.1;Late spermatids: 132.5;Respiratory ciliated cells: 177.2;Spermatocytes: 115.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 8.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 77.1;THP-1: 70.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031206, HPA031207" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA031206: AB_10599710, HPA031207: AB_10599946" "unprognostic (1.36e-2)" "unprognostic (9.04e-2)" "unprognostic (1.09e-1)" "unprognostic (2.84e-2)" "unprognostic (3.13e-2)" "unprognostic (1.21e-1)" "unprognostic (4.47e-2)" "unprognostic (9.86e-2)" "unprognostic (2.85e-2)" "unprognostic (3.02e-1)" "unprognostic (4.34e-3)" "unprognostic (8.41e-2)" "unprognostic (1.48e-2)" "unprognostic (2.25e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (6.51e-4)" "unprognostic (4.88e-2)" 13.0 10.6 11.5 6.7 13.8 14.4 16.0 14.4 21.9 8.7 26.7 6.8 3.3 21.2 17.5 10.5 36.1 14.7 15.0 11.4 14.4 11.1 5.6 12.6 9.6 18.1 16.9 11.3 9.0 15.4 8.5 16.8 13.9 8.9 12.4 17.7 8.8 13.1 19.7 6.9 7.4 11.4 14.9 7.5 12.4 28.0 12.9 7.4 26.8 7.5 10.7 8.2 4.9 16.3 7.3 9.1 20.3 5.2 7.2 16.7 24.7 9.2 9.7 11.5 10.6 23.5 19.5 25.3 19.2 11.6 12.2 5.7 8.2 5.3 7.1 2.7 5.0 12.4 41.3 10.7 15.2 12.8 77.1 14.6 11.0 15.5 14.4 13.7 18.0 0.7 48.0 20.1 10.0 7.6 2.6 34.6 26.0 10.4 6.9 48.4 3.1 6.8 29.0 12.3 15.9 21.4 16.0 6.1 13.6 22.7 5.9 70.5 2.8 14.1 5.3 7.9 33.7 6.9 12.4 17.2 11.2 35.9 11.7 0.9 1.3 2.3 0.4 1.4 0.5 3.1 0.5 0.3 4.3 3.3 0.4 0.4 3.8 2.3 1.1 8.7 0.6 1.0 11.5 13.8 14.4 21.9 11.4 14.4 18.1 16.9 13.9 14.9 12.9 16.3 13.3 3.2 14.5 76.0 11.5 5.1 11.8 17.2 10.2 12.6 11.6 11.0 58.6 8.6 23.0 23.9 14.6 16.3 9.3 5.4 50.9 8.2 112.3 103.1 18.5 11.7 18.8 17.2 54.6 10.8 46.3 15.5 11.2 11.1 0.0 13.6 12.5 7.3 11.2 5.0 90.3 6.5 22.4 21.3 6.5 132.5 9.0 13.2 7.2 42.2 6.6 19.2 1.0 74.9 75.9 5.6 6.6 6.4 12.0 7.1 2.7 35.6 177.2 19.1 6.6 15.5 15.8 115.9 30.6 5.4 3.0 34.2 7.5 8.3 6.9 10.6 EFR3A KIAA0143 ENSG00000132294 "EFR3 homolog A" Q14156 8 131904093-132013642 "Predicted intracellular proteins" "Autism, Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "retina: 121.6" "Cell type enhanced" "Detected in all" "Bipolar cells: 358.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022859, HPA023092, HPA023402" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 54: Non-specific - Microtubule organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA022859: AB_1848029, HPA023092: AB_2293240, HPA023402: AB_1848031" "unprognostic (4.79e-2)" "unprognostic (6.54e-2)" "unprognostic (6.42e-2)" "unprognostic (4.37e-3)" "unprognostic (2.77e-1)" "unprognostic (3.44e-2)" "unprognostic (3.04e-1)" "unprognostic (3.02e-1)" "unprognostic (1.51e-1)" "unprognostic (8.11e-2)" "unprognostic (5.89e-3)" "unprognostic (5.22e-2)" "unprognostic (3.46e-1)" "unprognostic (3.00e-1)" "unprognostic (3.29e-2)" "unprognostic (1.29e-1)" "unprognostic (2.21e-3)" 21.7 20.8 22.7 20.8 28.6 14.5 20.0 36.4 35.7 28.3 13.2 21.2 23.2 23.4 38.0 27.5 24.2 21.8 33.9 29.5 9.3 29.8 44.5 27.8 25.3 52.7 13.6 19.3 18.6 33.6 12.0 20.4 59.0 26.9 18.4 121.6 17.3 29.3 41.6 21.2 23.5 36.1 7.0 23.5 22.8 22.1 16.1 24.3 37.8 49.1 27.9 26.9 14.0 23.9 55.3 49.0 15.0 12.4 59.9 68.8 29.9 38.6 54.0 31.5 41.3 10.8 40.4 33.8 35.5 87.6 41.8 17.9 23.9 52.9 38.3 78.3 13.1 33.7 22.7 22.0 57.5 13.0 34.1 58.6 29.6 31.2 49.0 52.2 40.2 16.4 18.7 44.3 56.5 36.1 36.5 11.9 8.5 47.3 30.4 14.5 29.4 16.1 38.0 34.1 10.0 34.6 76.9 10.8 30.6 39.3 34.4 22.0 56.3 55.6 50.9 27.4 40.9 31.3 28.8 20.9 41.2 31.0 29.0 12.0 16.8 17.4 16.2 23.3 14.5 12.6 13.0 13.3 17.3 11.2 11.6 12.0 10.1 15.5 40.9 4.0 11.3 15.8 22.7 28.6 36.4 35.7 29.5 9.3 52.7 13.6 59.0 7.0 16.1 23.9 32.6 41.7 42.8 90.8 40.7 21.2 25.3 29.5 25.0 358.8 29.9 16.6 57.4 28.6 37.5 51.5 91.8 22.8 34.1 33.5 21.5 28.7 4.5 25.9 35.1 29.1 11.4 13.3 126.8 30.9 22.2 34.4 29.0 20.7 25.9 19.8 25.0 79.9 44.5 26.9 122.6 18.7 26.4 59.4 25.0 8.0 19.9 52.9 8.8 60.0 53.3 42.3 42.2 77.9 55.6 25.5 36.0 44.4 32.6 55.8 39.9 58.4 27.7 107.5 19.7 32.3 41.4 52.9 30.9 39.1 31.4 37.1 37.3 36.8 17.0 36.7 EGFR "ERBB, ERBB1" ENSG00000146648 "Epidermal growth factor receptor" P00533 7 55019017-55211628 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Host-virus interaction" "Developmental protein, Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 287.9;Skeletal myocytes: 251.2;Syncytiotrophoblasts: 376.8" "Cancer enhanced" "Detected in all" "glioma: 136.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 13 "A-431: 5282.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000035, HPA001200, HPA018530, CAB068186, CAB073534" Enhanced Enhanced "Plasma membrane,Cell Junctions" "Secreted to blood" NA NA 4740000 88000000 "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cell Junctions" "CAB000035: , CAB068186: AB_2665679, CAB073534: , HPA001200: AB_1078723, HPA018530: AB_1848044" "unprognostic (2.62e-2)" "unprognostic (9.56e-3)" "unprognostic (1.59e-1)" "unprognostic (7.51e-2)" "unprognostic (1.08e-1)" "unprognostic (1.27e-2)" "unprognostic (6.11e-2)" "unprognostic (4.88e-2)" "unprognostic (2.85e-2)" "unprognostic (3.30e-3)" "unprognostic (1.78e-3)" "unprognostic (1.04e-1)" "unprognostic (1.93e-3)" "unprognostic (6.98e-3)" "unprognostic (1.72e-1)" "unprognostic (6.62e-2)" "prognostic unfavorable (2.04e-5)" 27.9 11.4 12.6 4.0 18.3 0.0 20.0 16.6 9.7 20.4 10.5 12.2 5.7 11.4 10.3 23.5 13.9 9.0 7.1 6.3 10.3 11.6 35.3 14.9 2.5 10.4 19.0 15.1 15.8 3.5 2.9 67.9 8.9 16.2 10.7 10.2 22.1 15.0 10.9 51.0 9.5 9.3 7.5 5.1 11.1 4.2 22.6 12.8 20.6 20.6 8.3 14.7 24.1 6.3 5282.1 61.9 16.5 22.4 102.7 63.5 16.7 47.9 68.7 30.8 23.8 11.5 54.2 2.7 11.4 43.8 130.7 197.1 0.4 230.2 37.1 2.2 3.6 0.1 27.3 3.4 27.0 0.0 0.2 31.2 205.4 74.1 409.9 45.5 4.0 0.0 0.0 0.5 68.0 3.0 0.1 0.1 5.1 21.2 30.4 0.1 9.1 0.2 38.1 52.6 0.8 20.0 42.7 50.6 9.3 16.8 4.9 12.0 15.6 27.1 7.2 215.7 45.8 0.1 4.8 3.1 37.9 1.6 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 18.3 16.6 9.7 6.3 10.3 10.4 19.0 8.9 7.5 22.6 6.3 16.4 96.1 49.9 147.6 1.2 85.8 77.1 101.5 116.1 3.5 12.1 30.4 11.1 47.1 50.6 22.0 6.2 287.9 0.0 45.9 0.0 32.9 4.9 25.9 57.2 12.5 4.2 8.0 1.2 24.3 37.1 91.6 22.4 39.8 0.0 50.6 6.8 79.5 28.3 0.0 107.5 21.6 48.8 7.7 11.6 5.8 128.3 1.9 17.8 40.3 1.6 90.0 0.0 63.3 1.4 54.8 19.9 133.5 0.0 75.4 14.1 13.4 21.7 3.8 78.9 251.2 34.7 2.4 2.5 73.3 89.9 376.8 2.2 41.9 24.9 55.8 EHBP1 "KIAA0903, NACSIN" ENSG00000115504 "EH domain binding protein 1" Q8NDI1 2 62673851-63046487 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 203.4;Early spermatids: 220.3;Excitatory neurons: 262.3;Inhibitory neurons: 245.4;Late spermatids: 495.6;Oligodendrocyte precursor cells: 226.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035468, HPA035469" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Cytosol "HPA035468: AB_10671513, HPA035469: AB_10601365" "unprognostic (5.39e-2)" "unprognostic (1.63e-3)" "unprognostic (8.78e-2)" "unprognostic (3.83e-3)" "unprognostic (1.43e-1)" "unprognostic (1.57e-2)" "unprognostic (1.36e-1)" "prognostic unfavorable (9.03e-4)" "unprognostic (1.78e-1)" "unprognostic (1.95e-1)" "unprognostic (3.33e-2)" "unprognostic (3.14e-1)" "unprognostic (3.13e-3)" "unprognostic (1.15e-2)" "unprognostic (1.29e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (1.95e-8)" 30.0 17.2 15.1 10.7 16.3 6.4 17.4 27.7 19.3 29.0 11.7 41.9 9.7 31.1 7.9 29.5 21.3 20.4 11.7 20.0 16.5 17.1 53.9 11.6 8.8 13.3 22.1 48.0 15.9 15.2 12.2 11.9 14.1 16.0 14.2 20.9 15.7 18.6 8.0 13.0 14.9 30.0 10.9 8.1 17.5 37.4 22.6 13.4 14.4 13.1 10.2 18.1 21.6 16.2 49.7 66.9 26.8 16.4 46.1 89.0 27.2 43.6 42.4 31.6 25.9 80.4 36.2 34.2 15.4 79.8 47.5 29.1 35.1 30.5 51.9 36.3 16.5 29.7 22.9 95.2 31.5 17.5 21.5 40.9 54.1 31.6 61.9 31.3 20.5 26.7 20.6 19.1 51.1 19.4 20.0 10.9 26.3 40.8 26.2 17.8 33.8 14.9 20.8 16.1 29.6 23.6 35.1 25.9 43.0 28.5 12.6 17.0 15.2 33.3 34.4 55.8 23.0 21.5 16.2 32.7 33.3 26.3 69.4 0.2 2.2 2.5 4.1 2.4 4.0 6.3 4.2 3.9 3.7 4.9 4.2 3.6 0.8 3.4 1.3 2.4 2.5 2.2 15.1 16.3 27.7 19.3 20.0 16.5 13.3 22.1 14.1 10.9 22.6 16.2 29.0 38.5 18.8 203.4 10.4 15.6 12.0 27.1 43.3 39.7 10.5 12.8 15.2 22.8 20.7 14.7 4.2 10.9 9.9 5.3 15.6 22.1 220.3 10.3 45.4 19.9 16.2 8.8 262.3 40.5 30.1 36.6 9.2 12.1 2.5 15.2 30.0 59.6 5.0 18.5 245.4 5.4 6.1 8.6 11.4 495.6 58.4 7.6 10.6 119.0 6.5 20.1 13.4 226.7 98.7 41.7 5.0 40.3 9.6 13.9 11.4 15.1 14.5 17.8 6.6 33.1 19.4 53.7 31.1 55.4 14.2 2.9 12.7 18.2 8.1 13.1 EHBP1L1 "DKFZp762C186, TANGERIN" ENSG00000173442 "EH domain binding protein 1 like 1" Q8N3D4 11 65576046-65592650 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skeletal muscle: 255.7" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.1;Kupffer cells: 79.7;Macrophages: 67.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA039479, HPA073476" Enhanced Approved "Vesicles,Plasma membrane" NA NA 110000 "Cluster 59: Non-specific - Translation" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Vesicles, Plasma membrane" "HPA039479: AB_10795678, HPA073476: " "unprognostic (1.87e-2)" "unprognostic (1.10e-1)" "unprognostic (1.48e-2)" "unprognostic (7.73e-3)" "unprognostic (1.31e-1)" "unprognostic (2.84e-1)" "unprognostic (2.41e-3)" "unprognostic (2.35e-1)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.36e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (1.45e-4)" "unprognostic (6.10e-3)" "unprognostic (5.02e-2)" "unprognostic (3.50e-2)" "unprognostic (1.10e-1)" 27.2 9.9 7.5 51.9 6.2 59.7 21.5 5.9 9.4 35.9 7.3 108.1 26.0 56.1 5.7 45.4 48.0 18.0 45.6 7.1 6.3 17.7 10.8 39.6 30.7 9.8 8.1 19.6 8.1 4.1 9.8 16.3 7.7 45.2 12.2 0.4 22.9 39.5 255.7 22.6 46.6 32.8 8.0 73.3 41.0 7.3 9.4 14.5 13.0 70.7 16.6 71.3 40.8 9.0 40.6 41.0 1.3 21.8 10.5 26.4 8.2 31.4 22.9 14.8 7.8 13.7 34.9 14.0 52.4 45.8 41.2 55.9 7.6 29.7 3.4 39.3 1.2 32.4 51.0 12.0 10.0 7.1 30.1 22.7 19.8 37.2 6.8 26.9 15.2 20.8 50.5 55.9 13.8 34.5 12.4 27.5 1.8 15.1 34.8 33.6 0.2 46.8 13.7 20.0 0.9 17.2 17.4 15.2 32.9 3.0 21.9 33.7 26.3 40.3 42.9 57.3 0.6 98.5 66.6 7.3 60.2 18.8 23.9 0.0 0.3 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.1 0.1 0.0 0.0 7.5 6.2 5.9 9.4 7.1 6.3 9.8 8.1 7.7 8.0 9.4 9.0 33.1 0.0 6.9 6.2 23.9 10.1 8.5 2.9 15.9 1.4 12.2 14.2 22.0 7.2 7.4 1.8 0.0 3.4 27.3 79.1 0.0 3.6 0.2 11.9 12.2 26.0 4.2 61.6 4.4 5.1 1.4 13.8 61.2 14.2 2.5 5.3 18.9 5.7 32.6 0.0 2.2 16.3 2.0 79.7 33.9 1.7 11.5 67.6 7.2 15.0 49.1 0.7 20.6 1.5 1.3 27.8 53.0 38.0 19.5 11.6 19.5 0.4 8.6 1.1 26.3 27.3 30.7 2.7 5.9 15.3 14.8 2.6 23.2 23.0 21.9 17.0 EIF5AL1 "bA342M3.3, EIF5AP1" ENSG00000253626 "Eukaryotic translation initiation factor 5A like 1" Q6IS14 10 79512533-79516440 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein biosynthesis, Protein transport, Translocation, Transport" "Elongation factor, RNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 7 "testis: 10.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 79.2;Intestinal goblet cells: 96.7;Spermatocytes: 76.5;Undifferentiated cells: 121.3" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "U-251 MG: 2.2" HPA074052 Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 83: Testis - Spermatogenesis" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 53: Intestinal epithelial cells - Unknown function" Cytosol "Plasma membrane" "HPA074052: " "unprognostic (2.16e-2)" "prognostic favorable (4.23e-4)" "unprognostic (2.55e-1)" "unprognostic (4.14e-3)" "unprognostic (1.50e-1)" "unprognostic (3.48e-2)" "unprognostic (4.25e-2)" "unprognostic (2.50e-3)" "unprognostic (2.04e-2)" "unprognostic (3.57e-1)" "unprognostic (1.01e-1)" "unprognostic (8.79e-3)" "unprognostic (1.56e-1)" "unprognostic (8.63e-2)" "unprognostic (1.87e-1)" "unprognostic (6.68e-2)" "unprognostic (1.81e-1)" 0.8 0.8 0.1 0.2 0.1 0.2 0.6 0.5 0.3 0.4 0.0 0.6 0.2 0.5 0.2 1.4 0.4 0.0 0.9 0.1 0.0 0.5 1.3 0.6 0.3 0.0 0.0 0.3 0.7 0.2 0.4 0.0 0.0 0.5 0.2 0.8 0.5 0.0 1.5 1.0 0.5 0.0 0.0 0.5 0.5 10.6 0.0 0.0 0.5 0.0 0.3 0.5 0.7 0.1 0.4 0.8 0.3 1.7 0.0 0.2 0.3 0.3 0.1 0.3 0.2 0.6 0.3 0.9 0.3 0.0 0.2 0.5 0.1 0.0 0.2 0.2 0.7 0.2 1.0 0.4 0.1 0.3 0.6 0.0 0.0 0.1 0.1 0.0 0.2 0.1 0.2 0.3 0.1 0.6 1.0 0.9 1.2 0.1 0.1 0.3 0.7 0.6 0.5 0.8 0.2 0.5 0.5 0.4 0.6 0.1 0.8 0.7 0.2 0.4 1.0 1.1 2.2 0.4 0.5 0.8 0.7 0.2 0.6 1.1 0.8 0.6 1.2 2.0 1.4 1.3 1.2 1.3 1.6 1.3 0.9 1.3 0.7 1.7 1.3 2.5 1.0 0.8 0.1 0.1 0.5 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.8 16.0 30.0 1.3 10.4 33.8 3.0 7.8 0.0 0.6 5.1 2.4 43.1 2.8 16.1 0.0 0.0 20.8 2.4 79.2 11.7 64.5 14.7 2.9 4.4 12.9 60.0 10.7 0.6 47.8 35.1 15.5 0.0 3.2 48.2 0.9 4.2 5.1 17.5 1.7 0.6 96.7 8.2 8.7 27.9 8.7 5.0 7.2 19.6 0.0 41.9 1.2 13.4 0.0 1.0 65.6 61.2 3.0 0.5 10.3 66.5 11.1 6.1 0.5 0.0 6.9 25.9 76.5 4.3 0.0 34.5 27.6 8.9 3.3 121.3 5.0 EIF5B "DKFZp434I036, FLJ10524, IF2, KIAA0741" ENSG00000158417 "Eukaryotic translation initiation factor 5B" O60841 2 99337371-99401326 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Protein biosynthesis" "Hydrolase, Initiation factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 769.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA034648, HPA040095" Approved Approved "Plasma membrane,Cytosol" NA Yes 210000 "Cluster 6: Non-specific - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 1: K-562 - Erythropoiesis" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA034648: AB_10601902, HPA040095: AB_2676843" "unprognostic (1.23e-1)" "unprognostic (6.94e-2)" "unprognostic (2.01e-1)" "unprognostic (5.03e-2)" "unprognostic (4.65e-2)" "unprognostic (5.88e-3)" "prognostic unfavorable (7.15e-10)" "unprognostic (6.80e-2)" "unprognostic (9.84e-3)" "prognostic favorable (8.99e-4)" "unprognostic (1.68e-2)" "unprognostic (2.36e-1)" "prognostic unfavorable (1.42e-6)" "unprognostic (6.89e-2)" "unprognostic (3.24e-2)" "unprognostic (1.43e-1)" "unprognostic (7.93e-3)" 39.4 31.6 50.3 32.8 53.5 20.8 33.9 50.8 88.8 31.3 51.1 56.3 23.1 35.2 41.7 44.4 29.6 18.5 89.6 48.8 55.3 50.9 38.4 30.9 32.6 54.1 52.5 27.0 48.6 32.1 28.2 29.6 55.0 44.0 30.0 23.8 36.5 33.5 102.9 39.4 29.1 28.7 52.8 30.7 42.1 48.6 53.6 26.2 29.3 56.2 36.6 47.8 33.7 53.0 117.0 57.2 63.8 83.5 75.5 88.7 105.4 100.4 62.9 65.3 64.6 132.5 80.9 132.5 84.6 75.2 77.4 64.9 112.6 97.3 114.6 80.8 67.4 159.6 57.7 175.9 59.7 158.0 94.3 60.2 66.8 91.0 92.1 55.9 96.6 80.0 179.6 64.4 95.2 94.9 100.8 145.7 99.5 76.2 83.0 86.8 94.7 108.2 134.9 96.2 53.8 50.9 54.6 123.8 85.3 120.4 50.5 103.0 106.9 100.7 99.3 53.2 90.7 47.4 72.0 106.0 73.3 172.0 75.9 19.8 11.0 13.7 15.5 12.5 18.2 20.9 16.3 15.5 8.4 19.8 15.9 17.0 2.9 18.3 17.3 26.2 12.5 6.4 50.3 53.5 50.8 88.8 48.8 55.3 54.1 52.5 55.0 52.8 53.6 53.0 121.7 109.0 219.6 23.8 152.4 321.3 200.4 209.0 84.8 103.8 159.1 112.1 579.1 135.8 198.6 343.9 50.1 143.7 142.9 135.0 144.8 210.5 769.9 143.1 175.0 153.2 157.9 154.2 27.4 235.1 205.3 130.4 82.0 157.5 172.7 90.0 146.3 480.9 134.7 77.4 28.3 206.7 144.5 123.5 128.9 144.0 124.5 95.7 142.3 18.7 157.7 91.8 145.2 21.6 36.7 282.6 93.8 175.7 183.2 253.9 102.7 226.2 165.4 111.3 276.1 167.3 157.7 575.3 505.0 99.1 324.8 181.4 133.4 101.7 185.1 244.7 ELMO3 "CED-12, CED12, ELMO-3, FLJ13824" ENSG00000102890 "Engulfment and cell motility 3" Q96BJ8 16 67199111-67204029 "Predicted intracellular proteins" "Apoptosis, Phagocytosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 63.9;Paneth cells: 50.3;Proximal enterocytes: 100.3;Undifferentiated cells: 52.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 33.1;CAPAN-2: 49.3;HaCaT: 46.9;T-47d: 45.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA021484 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cell Junctions" "HPA021484: AB_1848129" "unprognostic (4.49e-3)" "unprognostic (2.04e-1)" "unprognostic (1.10e-2)" "unprognostic (8.08e-2)" "unprognostic (1.39e-1)" "unprognostic (6.16e-3)" "unprognostic (3.14e-1)" "unprognostic (8.17e-3)" "unprognostic (1.73e-1)" "unprognostic (8.06e-2)" "unprognostic (3.40e-2)" "unprognostic (6.95e-3)" "prognostic favorable (2.77e-5)" "unprognostic (3.47e-1)" "unprognostic (2.66e-1)" "unprognostic (1.84e-1)" "unprognostic (1.97e-2)" 2.8 1.8 1.5 4.3 1.4 5.6 8.8 2.4 2.6 6.4 0.3 24.3 33.1 2.0 4.1 25.8 8.5 8.6 1.9 1.1 1.7 21.4 8.1 8.3 2.9 2.1 1.0 1.8 41.0 8.5 29.8 7.1 2.8 19.3 9.1 0.7 20.3 9.6 1.2 33.5 26.3 0.8 0.4 5.6 26.0 13.0 1.3 2.1 19.3 0.3 2.6 8.5 13.2 1.5 22.1 2.5 2.4 3.0 0.4 0.6 33.1 1.3 0.7 1.6 1.4 14.2 49.3 3.0 1.5 0.7 0.7 46.9 2.2 21.6 0.3 1.4 2.9 3.2 4.8 4.7 1.0 1.9 7.5 0.5 15.6 1.2 1.1 1.6 1.7 2.6 3.1 1.5 0.9 18.4 2.0 9.3 3.2 20.7 1.9 4.6 2.3 4.9 2.0 2.9 16.2 3.6 3.2 14.4 1.5 1.3 45.8 3.4 2.8 3.7 4.5 2.3 2.3 4.9 1.7 5.8 1.9 4.4 1.8 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.3 0.0 0.0 0.1 0.1 0.0 1.5 1.4 2.4 2.6 1.1 1.7 2.1 1.0 2.8 0.4 1.3 1.5 1.8 0.0 13.1 0.0 2.0 8.8 11.9 21.9 13.1 0.9 20.6 16.3 1.2 15.7 12.6 20.2 0.0 33.8 1.0 63.9 17.6 20.1 22.9 8.8 1.7 1.6 13.1 6.9 0.4 24.0 15.0 1.7 47.4 12.2 4.5 1.3 1.4 3.6 3.6 0.0 0.3 33.8 22.4 1.6 3.1 36.3 0.9 2.6 3.6 1.9 2.8 0.4 0.0 0.0 1.0 24.8 50.3 0.7 1.4 7.9 100.3 28.6 12.3 1.5 0.0 0.4 1.6 14.5 5.9 14.4 13.5 16.8 2.3 5.0 52.3 13.0 EMP3 YMP ENSG00000142227 "Epithelial membrane protein 3" P54852 19 48321509-48330553 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 2037.4;Macrophages: 699.2;Melanocytes: 1117.1" "Cancer enhanced" "Detected in all" "melanoma: 195.4" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "NB-4: 1472.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA062030 Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 24: NB-4 - Immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA062030: " "unprognostic (5.06e-3)" "unprognostic (4.41e-1)" "unprognostic (1.83e-1)" "unprognostic (9.28e-3)" "unprognostic (1.33e-2)" "unprognostic (4.83e-3)" "unprognostic (1.49e-2)" "unprognostic (1.02e-1)" "unprognostic (9.31e-2)" "unprognostic (4.72e-2)" "unprognostic (3.41e-2)" "unprognostic (1.79e-1)" "prognostic unfavorable (2.31e-7)" "prognostic unfavorable (3.13e-4)" "unprognostic (1.16e-1)" "unprognostic (2.41e-1)" "unprognostic (2.90e-3)" 107.7 85.6 37.6 115.8 37.4 325.1 68.8 37.9 41.0 149.6 36.9 166.7 36.9 143.9 60.7 37.1 96.2 72.5 100.9 38.6 53.8 51.8 29.1 141.0 86.1 52.1 43.9 110.8 18.4 17.1 21.4 67.1 46.9 61.3 65.5 9.2 41.8 90.1 21.7 61.6 81.6 202.9 44.2 91.8 65.3 33.5 43.7 45.2 43.2 43.7 94.7 132.8 106.9 48.4 73.8 739.3 44.9 127.1 691.3 1081.5 1.2 490.7 898.0 627.6 560.7 73.5 265.0 6.9 107.5 1101.0 296.4 12.1 45.5 54.6 390.4 241.3 20.5 335.0 192.0 43.3 572.4 160.2 338.9 586.1 12.2 635.3 436.3 455.5 277.9 66.1 237.4 616.1 1019.5 10.1 25.1 1472.4 55.4 12.1 196.9 22.1 150.1 355.7 554.6 0.4 1.8 2.0 225.2 1.2 131.2 77.2 2.7 253.1 456.6 574.7 236.5 435.8 388.1 287.6 426.6 20.1 339.2 232.5 402.5 2401.3 980.4 1402.3 1324.0 1173.0 1117.1 570.1 1425.3 1327.0 688.7 467.9 818.8 948.4 1094.0 854.5 1148.4 516.9 1631.4 1971.4 37.6 37.4 37.9 41.0 38.6 53.8 52.1 43.9 46.9 44.2 43.7 48.4 66.5 0.0 4.5 5.5 338.0 278.0 75.4 161.0 48.3 2.3 14.7 22.9 5.4 21.5 21.8 33.1 0.0 14.9 375.9 1.5 5.9 72.0 6.5 18.9 255.1 118.6 6.0 94.8 0.2 11.2 26.0 371.3 23.0 15.1 257.0 8.5 128.2 7.2 589.0 0.0 0.3 4.1 42.7 458.8 2037.4 21.3 335.5 699.2 1117.1 6.5 444.5 64.6 565.4 0.0 0.7 114.3 28.2 217.0 334.9 285.5 1.7 9.3 14.6 5.0 105.2 193.0 278.7 16.2 6.7 10.6 189.9 20.2 441.4 29.1 4.9 44.4 ENG "CD105, END, HHT1, ORW, ORW1" ENSG00000106991 Endoglin P17813 9 127815013-127854658 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Angiogenesis, Cell adhesion" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 528.7" "Cell type enhanced" "Detected in many" "Adipocytes: 407.5;Endothelial cells: 514.4;Extravillous trophoblasts: 294.4;Hepatic stellate cells: 579.0;Leydig cells: 487.1;Peritubular cells: 1421.8;Syncytiotrophoblasts: 376.4;Theca cells: 308.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 19.9;intermediate monocyte: 28.2;myeloid DC: 10.3;NK-cell: 7.6;non-classical monocyte: 22.1" "Group enriched" "Detected in many" 4 "dendritic cells: 10.3;monocytes: 28.2;NK-cells: 7.6" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 263.8;HUVEC TERT2: 487.4;TIME: 1027.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000096, HPA011862, HPA067440, CAB072873" Enhanced Supported "Nuclear bodies,Plasma membrane" NA NA 280000000 "Cluster 7: Monocytes - Unknown function" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Nuclear bodies" "CAB000096: AB_563482, CAB072873: AB_2665725, HPA011862: AB_1846217, HPA067440: AB_2685840" "unprognostic (2.28e-1)" "unprognostic (1.13e-1)" "unprognostic (3.87e-2)" "unprognostic (2.96e-2)" "unprognostic (1.77e-1)" "prognostic favorable (6.61e-4)" "prognostic favorable (5.62e-6)" "unprognostic (2.15e-1)" "unprognostic (4.06e-1)" "unprognostic (3.87e-2)" "unprognostic (2.20e-2)" "unprognostic (8.98e-2)" "prognostic unfavorable (4.26e-4)" "unprognostic (3.33e-3)" "unprognostic (7.35e-2)" "unprognostic (2.84e-1)" "unprognostic (1.27e-1)" 234.5 92.6 44.4 80.2 41.5 18.8 164.8 45.2 44.5 129.7 50.4 62.4 33.2 111.1 35.1 43.1 122.4 58.7 528.7 36.7 43.1 211.6 60.7 260.7 43.4 50.0 47.1 220.9 47.1 29.7 56.1 93.6 52.8 93.9 17.5 2.1 46.2 73.5 72.3 51.3 76.8 65.7 43.1 226.5 57.6 98.9 59.4 17.3 169.2 54.8 17.7 93.0 95.8 43.6 1.3 1.0 7.1 0.4 117.8 81.0 217.8 147.1 102.0 74.4 43.4 0.5 1.3 1.0 70.2 263.8 56.8 2.4 0.0 23.2 24.5 0.7 0.3 42.3 76.7 4.6 91.7 20.2 0.5 137.6 5.4 97.7 34.9 1.0 487.4 1.4 0.7 1.4 88.1 0.9 0.6 1.8 1.7 0.3 4.2 66.9 12.5 1.4 0.0 0.4 0.8 1.8 78.0 65.3 20.1 4.7 13.8 29.8 1027.5 248.1 13.7 164.7 0.7 5.2 1.2 0.9 67.1 52.0 83.2 0.0 19.9 0.5 1.8 28.2 0.6 0.6 3.0 3.4 10.3 1.4 1.9 3.0 0.5 7.6 22.1 3.8 1.2 8.4 44.4 41.5 45.2 44.5 36.7 43.1 50.0 47.1 52.8 43.1 59.4 43.6 407.5 3.2 16.0 2.0 9.2 12.0 2.3 2.1 2.8 2.8 9.5 9.8 28.4 18.6 2.3 3.7 4.2 30.0 8.6 0.4 0.0 10.2 8.6 7.7 67.9 514.4 2.4 49.2 0.6 1.1 294.4 85.7 3.1 8.1 15.2 0.8 579.0 9.8 132.0 0.0 0.7 1.6 0.0 65.4 29.7 51.4 487.1 56.6 24.9 78.7 36.2 2.0 4.1 1.5 1.1 1.4 0.0 1421.8 2.1 2.0 0.0 0.3 5.1 4.6 72.3 44.0 57.5 4.4 5.2 1.3 8.4 376.4 9.6 308.1 0.5 1.4 ENO1 "ENO1L1, MBP-1, MPB1, PPH" ENSG00000074800 "Enolase 1" P06733 1 8861000-8879190 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Glycolysis, Plasminogen activation, Transcription, Transcription regulation" "DNA-binding, Lyase, Repressor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 2259.3;Extravillous trophoblasts: 2078.5;Muller glia cells: 2624.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018614, HPA068284, HPA068721, CAB069394, CAB080034" Supported Enhanced "Plasma membrane,Cytosol" NA NA 310000000 "Cluster 39: Non-specific - mRNA processing" "Cluster 27: Brain & Skin - Unknown function" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB018614: AB_2099061, CAB069394: , CAB080034: , HPA068284: , HPA068721: AB_2732119" "unprognostic (6.51e-3)" "unprognostic (9.50e-3)" "unprognostic (3.56e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (2.71e-4)" "unprognostic (1.82e-2)" "prognostic unfavorable (1.30e-8)" "unprognostic (2.37e-2)" "unprognostic (5.58e-2)" "unprognostic (9.72e-2)" "unprognostic (1.67e-2)" "unprognostic (1.46e-1)" "unprognostic (7.53e-2)" "unprognostic (6.20e-2)" "unprognostic (1.97e-1)" "unprognostic (2.22e-1)" "unprognostic (1.36e-3)" 463.4 418.4 552.9 553.3 591.7 792.8 409.1 679.7 749.9 370.7 585.6 382.6 401.2 321.7 125.7 1049.4 281.6 302.0 328.2 638.1 599.6 1063.6 612.2 453.2 492.4 624.1 607.7 295.0 220.8 347.2 245.7 362.7 602.9 279.2 358.3 741.5 581.3 354.2 231.0 548.1 382.3 471.3 583.4 394.9 321.6 217.7 585.3 455.6 271.4 146.5 695.4 485.9 519.7 571.5 3637.0 3088.4 1461.8 1258.6 1194.2 1323.8 1316.6 1919.1 2110.9 4044.1 3767.4 1986.9 2041.5 2586.5 2496.8 2328.5 1651.8 1736.8 2511.5 5127.7 4081.0 1780.5 2645.9 2191.3 2848.0 2511.0 1789.6 4421.6 1290.1 1377.4 1526.1 3208.9 4825.9 3045.2 2630.1 1294.6 2444.4 982.3 2664.2 1784.1 1685.2 2354.5 1600.3 1290.4 3063.4 1712.4 2172.9 4259.0 4815.0 843.6 1961.4 1211.1 2251.0 3232.5 2407.8 1748.4 1621.8 1302.1 2424.7 2774.5 2444.5 2402.3 3328.3 2771.0 2120.4 3906.9 4313.8 3556.1 2388.6 195.9 1198.7 232.3 528.4 822.7 597.3 411.2 552.5 543.2 1216.4 386.1 443.4 466.0 230.6 635.3 830.6 336.1 700.0 2171.2 552.9 591.7 679.7 749.9 638.1 599.6 624.1 607.7 602.9 583.4 585.3 571.5 140.0 278.9 499.1 99.6 222.3 416.5 570.9 1939.8 348.8 178.2 242.7 324.6 69.6 283.1 657.4 606.9 70.9 1045.4 194.0 455.9 925.4 2259.3 281.3 205.3 227.7 314.3 189.0 145.4 32.0 1399.1 2078.5 303.5 144.8 248.4 297.2 408.6 133.5 351.7 1147.4 482.9 33.2 297.3 787.3 356.4 524.5 699.6 171.5 454.2 448.2 30.9 1558.2 2624.9 279.1 28.6 26.9 1433.6 366.9 135.1 211.0 555.7 742.2 1005.4 245.7 216.6 151.2 156.1 402.5 215.1 154.3 468.1 349.6 1001.8 285.6 609.8 528.4 444.2 ENO2 ENSG00000111674 "Enolase 2" P09104 12 6913745-6923698 "Cancer-related genes, Candidate cardiovascular disease genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Glycolysis Lyase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "retina: 1695.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 318.2;Cone photoreceptor cells: 312.8;Horizontal cells: 429.0;Rod photoreceptor cells: 787.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 9.9;MAIT T-cell: 11.3;memory B-cell: 6.8;memory CD4 T-cell: 13.1;memory CD8 T-cell: 11.4;naive B-cell: 4.4;naive CD4 T-cell: 8.2;naive CD8 T-cell: 8.6;neutrophil: 7.0;T-reg: 7.5" "Group enriched" "Detected in many" 7 "B-cells: 6.8;granulocytes: 7.0;T-cells: 13.1" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 537.4;U-87 MG: 398.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000063, HPA068284, HPA068721, CAB073539, CAB079023" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 55000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB000063: AB_2099322, CAB073539: , CAB079023: , HPA068284: , HPA068721: AB_2732119" "unprognostic (8.96e-2)" "unprognostic (8.28e-2)" "prognostic unfavorable (6.96e-4)" "unprognostic (1.28e-1)" "unprognostic (7.95e-3)" "unprognostic (1.39e-2)" "prognostic unfavorable (5.15e-4)" "unprognostic (1.48e-1)" "unprognostic (9.43e-2)" "unprognostic (1.58e-1)" "unprognostic (1.98e-1)" "unprognostic (2.02e-2)" "prognostic unfavorable (7.89e-11)" "unprognostic (7.61e-2)" "unprognostic (3.06e-1)" "unprognostic (8.10e-3)" "unprognostic (1.24e-1)" 25.6 46.7 280.8 20.0 289.7 9.6 20.2 291.2 400.7 55.9 97.5 74.0 10.2 40.1 12.6 15.3 40.2 17.9 53.7 295.0 289.4 27.8 7.7 33.8 26.3 289.4 189.9 29.7 9.0 43.6 124.4 10.4 282.2 34.9 15.5 1695.6 13.8 34.4 7.4 19.3 37.1 35.0 164.3 26.4 30.4 9.6 259.0 26.7 42.0 6.4 24.4 57.4 44.1 306.2 74.3 45.3 16.2 0.5 23.7 26.0 1.5 56.5 37.3 82.0 125.9 8.6 5.8 103.9 9.5 24.3 108.8 11.0 173.0 15.4 116.1 211.9 16.6 141.0 47.7 60.3 17.4 8.3 161.2 13.0 0.7 61.1 11.5 537.4 17.5 137.9 9.5 1.1 56.3 10.3 66.9 8.8 84.9 31.7 27.2 75.0 13.9 22.9 38.5 9.8 128.3 94.0 14.3 1.0 96.3 76.4 4.5 3.9 20.9 69.4 73.7 95.7 73.0 73.3 79.5 15.4 398.4 0.3 15.2 2.1 0.0 0.2 9.9 0.0 11.3 6.8 13.1 11.4 0.1 4.4 8.2 8.6 7.0 0.4 0.3 1.2 7.5 6.1 280.8 289.7 291.2 400.7 295.0 289.4 289.4 189.9 282.2 164.3 259.0 306.2 3.2 35.3 27.4 54.2 11.2 6.2 2.3 45.2 1.8 318.2 5.2 4.3 16.1 1.5 17.2 12.9 312.8 0.3 7.5 0.3 0.0 17.0 0.5 9.6 2.1 9.9 23.9 7.0 96.2 1.8 1.1 8.3 2.0 2.7 67.2 1.0 5.3 0.2 1.7 429.0 89.4 0.5 18.3 0.6 6.9 0.3 5.6 5.9 12.4 25.3 3.5 146.1 0.0 23.6 31.5 9.3 1.2 9.8 9.2 2.5 0.1 0.2 32.2 787.2 13.1 8.1 20.2 1.5 2.5 1.1 2.3 0.3 17.1 0.3 0.4 2.2 ENO3 ENSG00000108515 "Enolase 3" P13929 17 4948092-4957131 "Candidate cardiovascular disease genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Glycolysis Lyase "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 26 "skeletal muscle: 14758.3;tongue: 10771.0" "Group enriched" "Detected in many" 5 "Cardiomyocytes: 582.2;Skeletal myocytes: 248.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 263.8;HeLa: 120.0;HMC-1: 115.1;RH-30: 170.2;RPMI-8226: 96.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000793, HPA068284, HPA068721" Enhanced Supported "Plasma membrane,Cytosol" Yes No 86000000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 44: HDLM-2 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA000793: AB_1078742, HPA068284: , HPA068721: AB_2732119" "unprognostic (7.35e-2)" "unprognostic (5.25e-2)" "prognostic unfavorable (7.33e-4)" "unprognostic (1.57e-1)" "unprognostic (1.29e-1)" "unprognostic (5.86e-2)" "unprognostic (5.68e-2)" "unprognostic (2.08e-2)" "unprognostic (8.12e-2)" "unprognostic (1.42e-1)" "unprognostic (6.04e-3)" "unprognostic (2.21e-2)" "unprognostic (4.63e-2)" "unprognostic (5.34e-2)" "unprognostic (3.48e-1)" "unprognostic (2.15e-1)" "unprognostic (4.50e-2)" 7.8 5.5 3.8 15.6 3.9 20.4 8.0 7.1 4.3 6.6 5.0 8.0 20.1 7.2 7.1 173.8 7.4 2.6 499.8 3.5 3.7 10.3 108.0 8.6 13.0 4.3 5.0 6.0 5.5 4.0 7.9 6.3 4.6 47.3 3.0 5.0 116.8 3.1 14758.3 8.3 15.6 2.8 4.1 16.9 10.1 9.3 4.3 5.8 10.3 10771.0 4.9 5.6 5.0 4.9 12.0 25.5 11.3 10.7 9.1 2.2 27.6 21.0 2.7 1.5 1.3 12.8 8.1 21.9 25.8 1.9 3.5 15.4 3.8 1.9 1.0 263.8 24.3 21.9 120.0 18.9 3.7 6.8 115.1 14.4 3.8 2.1 4.1 9.8 1.4 24.8 10.2 39.0 4.9 6.6 7.9 26.5 14.8 3.3 10.6 34.6 170.2 96.9 3.1 7.9 7.1 27.1 13.6 11.4 14.7 7.6 10.2 7.0 6.5 12.1 21.3 5.4 16.0 27.6 16.8 18.2 6.7 20.8 12.2 31.4 28.5 50.4 36.8 41.5 24.8 24.5 30.8 34.4 37.6 20.1 20.0 32.2 34.4 34.9 47.6 29.9 43.2 83.6 3.8 3.9 7.1 4.3 3.5 3.7 4.3 5.0 4.6 4.1 4.3 4.9 1.2 0.0 1.8 2.3 2.7 2.0 1.2 2.1 4.0 6.6 3.0 3.0 582.2 0.0 2.2 5.5 4.2 5.4 3.2 2.9 0.0 1.5 1.8 0.9 1.6 7.3 0.0 3.8 0.2 0.8 3.8 17.3 4.6 2.2 8.2 2.4 2.2 56.2 4.5 3.3 0.2 2.2 2.0 3.5 6.7 3.7 0.3 4.3 1.8 0.0 78.3 1.9 4.1 1.0 0.5 1.8 1.9 0.4 2.3 1.2 6.6 9.5 0.3 2.5 6.6 248.4 55.8 7.9 7.5 2.1 1.8 3.3 4.5 1.1 2.6 0.8 ENOX2 "APK1, COVA1, tNOX" ENSG00000165675 "Ecto-NOX disulfide-thiol exchanger 2" Q16206 X 130622325-130903317 "Predicted intracellular proteins" "Biological rhythms, Electron transport, Growth regulation, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 51.3;Oligodendrocytes: 132.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000514, HPA003027" Uncertain Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA000514: AB_1078558, HPA003027: " "unprognostic (1.34e-2)" "unprognostic (7.02e-2)" "unprognostic (9.75e-2)" "unprognostic (1.08e-1)" "unprognostic (1.94e-1)" "unprognostic (2.60e-1)" "unprognostic (4.07e-2)" "unprognostic (6.07e-2)" "unprognostic (6.27e-3)" "unprognostic (5.22e-2)" "unprognostic (1.79e-1)" "unprognostic (1.44e-1)" "prognostic favorable (1.09e-5)" "unprognostic (6.42e-2)" "unprognostic (4.60e-2)" "unprognostic (3.02e-1)" "unprognostic (1.38e-1)" 6.4 7.6 6.4 5.6 9.2 3.3 6.4 5.5 6.9 6.9 5.0 4.9 4.1 8.8 5.4 7.2 7.6 6.6 10.8 6.1 8.0 4.3 5.4 5.1 8.2 7.5 6.7 7.9 3.8 7.8 1.7 5.9 6.4 6.1 5.3 2.8 4.6 8.0 6.7 4.4 4.7 8.2 6.2 7.3 5.6 5.9 7.6 8.6 6.3 8.3 9.5 6.9 3.0 9.2 15.7 12.9 16.2 7.4 15.3 13.2 7.3 12.6 15.3 8.5 5.3 6.0 12.9 11.3 30.1 11.6 11.4 10.9 11.4 13.0 10.7 15.3 12.1 24.6 7.4 6.6 10.6 20.2 16.6 10.7 19.3 10.1 11.3 4.0 12.8 9.9 17.1 8.6 7.0 21.4 13.2 3.7 9.0 20.8 16.0 8.7 10.4 12.9 10.0 10.5 5.5 9.6 12.2 7.2 17.0 6.1 4.6 10.1 10.5 8.3 4.9 13.2 26.4 9.2 4.9 7.6 23.6 19.2 13.8 7.0 11.1 12.9 9.4 14.1 9.6 11.7 10.5 9.7 10.8 11.9 11.2 9.7 1.8 10.8 7.7 5.8 12.4 9.3 6.4 9.2 5.5 6.9 6.1 8.0 7.5 6.7 6.4 6.2 7.6 9.2 11.8 3.2 7.4 15.0 11.5 4.2 6.9 5.1 19.4 4.4 8.1 5.3 13.0 5.7 7.5 3.7 0.0 6.2 7.9 4.9 7.9 8.0 1.0 8.3 13.3 8.6 4.8 11.6 18.7 9.3 5.5 9.7 10.7 5.4 6.3 7.4 7.5 12.3 6.9 3.3 31.2 6.7 14.2 21.3 7.7 2.2 5.6 12.6 8.8 23.4 18.4 4.3 19.6 51.3 132.2 10.1 2.6 6.4 11.9 6.4 4.5 8.4 13.1 8.3 6.6 11.6 9.5 11.4 10.6 13.8 4.8 7.3 11.1 7.6 5.7 5.7 EPB41L3 "4.1B, DAL1, KIAA0987" ENSG00000082397 "Erythrocyte membrane protein band 4.1 like 3" Q9Y2J2 18 5392381-5630700 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 171.9;Excitatory neurons: 306.8;Inhibitory neurons: 237.4;Late spermatids: 291.6;Oligodendrocytes: 159.2;Syncytiotrophoblasts: 214.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 7.7;non-classical monocyte: 12.4" "Lineage enriched" "Detected in many" 5 "monocytes: 12.4" "Cell line enhanced" "Detected in many" "ASC TERT1: 62.8;HUVEC TERT2: 59.5;SCLC-21H: 65.5;TIME: 164.8;U-2 OS: 57.7;U-2197: 57.1;U-251 MG: 71.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028605 Enhanced Enhanced "Plasma membrane,Cell Junctions" NA NA 100000 "Cluster 14: Monocytes - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA028605: AB_10611963" "unprognostic (3.58e-3)" "unprognostic (1.17e-2)" "unprognostic (3.61e-1)" "unprognostic (7.97e-2)" "unprognostic (1.88e-1)" "unprognostic (1.44e-2)" "unprognostic (2.60e-1)" "unprognostic (9.73e-2)" "unprognostic (3.40e-1)" "unprognostic (3.63e-3)" "unprognostic (1.07e-3)" "unprognostic (5.81e-2)" "unprognostic (5.96e-2)" "unprognostic (5.65e-3)" "unprognostic (8.99e-2)" "unprognostic (2.72e-2)" "unprognostic (6.59e-3)" 27.6 28.1 5.8 27.4 5.3 4.1 11.7 17.9 49.9 6.4 0.0 17.7 49.6 7.8 5.6 10.7 13.6 9.3 6.5 7.1 24.8 33.9 4.8 13.9 7.9 59.6 14.7 11.4 6.9 59.6 10.4 21.1 53.3 5.8 13.1 45.8 4.0 7.3 6.1 4.0 47.7 13.4 7.7 12.2 3.2 62.3 29.1 6.5 4.6 10.7 3.9 10.3 5.7 29.8 0.3 0.9 3.9 0.0 54.5 62.8 43.7 12.8 0.0 0.0 0.0 0.7 0.1 0.1 0.1 39.8 23.2 0.2 38.6 0.0 0.0 0.0 34.2 0.1 0.4 0.0 0.2 0.1 4.6 33.3 0.0 12.3 0.1 16.2 59.5 0.0 0.4 0.4 0.1 0.0 0.5 0.7 7.9 0.2 12.5 0.3 0.0 0.2 0.4 4.8 65.5 0.5 0.1 0.5 25.9 31.2 0.7 4.8 164.8 0.3 57.7 57.1 71.6 0.1 0.1 0.0 0.2 5.4 6.8 0.0 4.3 0.0 0.0 7.7 0.0 0.0 0.0 0.0 2.5 0.0 0.5 0.0 0.7 0.0 12.4 0.0 0.0 0.7 5.8 5.3 17.9 49.9 7.1 24.8 59.6 14.7 53.3 7.7 29.1 29.8 18.2 19.2 6.4 28.7 1.3 15.9 4.1 0.0 3.4 75.6 5.3 1.7 3.5 2.8 1.9 7.3 77.2 98.6 0.2 44.0 15.6 0.4 171.9 2.2 10.1 21.9 9.1 3.2 306.8 0.7 44.2 27.7 0.0 2.1 0.0 0.0 7.1 0.8 58.8 3.3 237.4 10.0 0.0 82.2 66.7 291.6 22.4 81.9 10.6 103.0 50.9 3.3 2.1 44.2 159.2 0.8 8.3 7.9 1.6 3.8 91.2 68.4 1.6 14.7 0.0 3.0 13.1 2.7 11.5 2.3 8.4 214.0 2.6 0.2 12.3 1.7 EPB41L4A NBL4 ENSG00000129595 "Erythrocyte membrane protein band 4.1 like 4A" Q9HCS5 5 112142441-112419313 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cholangiocytes: 64.3;Oligodendrocyte precursor cells: 164.4;Oligodendrocytes: 65.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "EFO-21: 30.1;HeLa: 36.5;RT4: 21.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA036580 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 68: Epididymis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Nucleoplasm "HPA036580: AB_10669908" "unprognostic (1.40e-1)" "unprognostic (1.90e-1)" "unprognostic (1.92e-3)" "unprognostic (3.64e-2)" "unprognostic (4.73e-2)" "unprognostic (5.59e-3)" "unprognostic (4.40e-2)" "unprognostic (8.38e-2)" "unprognostic (1.90e-1)" "unprognostic (3.97e-2)" "unprognostic (1.22e-1)" "unprognostic (1.23e-3)" "prognostic favorable (3.65e-5)" "unprognostic (1.68e-1)" "unprognostic (3.35e-2)" "unprognostic (2.73e-1)" "unprognostic (1.92e-1)" 8.7 4.5 4.8 3.2 5.7 3.6 5.3 4.1 4.8 4.1 9.0 4.0 2.6 4.3 12.7 10.1 7.4 13.8 9.2 6.0 5.1 11.7 3.3 7.7 3.3 5.7 4.6 5.7 4.9 8.0 0.5 9.3 4.8 5.8 4.8 16.0 7.2 5.4 4.2 8.8 3.4 2.7 4.9 4.7 5.6 6.1 4.8 3.6 13.5 4.2 3.6 5.1 2.3 4.8 0.8 5.5 14.3 1.5 0.0 0.0 2.9 2.1 0.0 0.0 0.0 3.0 12.3 6.2 30.1 0.0 0.8 7.4 1.1 6.9 0.0 1.0 5.0 9.8 36.5 2.0 0.1 2.6 3.1 0.0 3.0 0.0 0.0 1.6 9.2 1.7 1.9 5.6 0.0 1.8 4.6 3.5 2.7 1.2 1.1 2.3 10.7 1.3 8.4 21.6 11.8 6.1 10.7 5.2 4.5 9.8 15.9 1.4 15.7 0.7 2.4 1.9 4.4 5.6 1.3 4.6 1.4 5.2 0.8 0.5 0.2 0.1 2.0 0.3 1.1 1.4 0.6 0.6 0.2 1.6 0.9 1.8 0.2 0.1 0.5 0.1 0.6 0.5 4.8 5.7 4.1 4.8 6.0 5.1 5.7 4.6 4.8 4.9 4.8 4.8 55.9 28.9 7.7 17.3 4.7 6.0 16.8 11.2 13.6 5.0 11.2 4.7 8.3 64.3 24.2 14.7 4.2 7.4 4.5 8.5 11.7 15.0 20.8 19.7 3.1 35.2 1.2 2.1 28.6 7.5 0.7 8.4 7.1 17.1 8.8 11.9 34.6 1.7 2.7 1.7 31.8 6.3 16.2 4.6 2.1 23.0 1.8 1.8 3.6 56.2 3.2 8.2 14.4 164.4 65.4 14.1 10.9 1.9 6.5 13.7 1.9 30.4 39.5 32.1 0.0 8.7 6.0 1.8 9.1 16.0 8.1 2.5 3.7 2.2 7.5 19.1 EPB41L4B "EHM2, LULU2" ENSG00000095203 "Erythrocyte membrane protein band 4.1 like 4B" Q9H329 9 109171974-109321059 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 88.9;pancreas: 149.1" "Cell type enhanced" "Detected in many" "Distal enterocytes: 134.8;Excitatory neurons: 79.7;Hepatocytes: 125.2;Proximal enterocytes: 79.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 31.7;hTCEpi: 49.8;OE19: 62.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042862 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA042862: AB_10794534" "prognostic unfavorable (1.02e-4)" "unprognostic (6.58e-2)" "unprognostic (2.33e-2)" "unprognostic (1.20e-1)" "unprognostic (2.31e-2)" "unprognostic (1.74e-1)" "unprognostic (2.40e-2)" "unprognostic (6.19e-2)" "unprognostic (2.72e-2)" "unprognostic (1.40e-1)" "unprognostic (3.60e-1)" "unprognostic (6.20e-2)" "unprognostic (8.82e-4)" "unprognostic (1.46e-3)" "unprognostic (1.43e-1)" "unprognostic (4.65e-2)" "unprognostic (1.29e-1)" 21.0 9.7 6.0 4.5 8.7 0.0 15.3 2.0 12.2 4.1 11.8 57.6 47.6 1.2 17.9 1.5 10.8 4.2 8.8 10.7 6.4 6.4 88.9 6.3 0.2 2.7 5.3 13.8 149.1 11.1 1.6 2.5 3.7 7.6 56.7 3.0 26.9 9.1 6.1 15.5 51.9 1.9 7.2 0.1 30.6 7.5 10.9 0.6 44.7 0.7 1.6 2.2 3.4 4.3 8.7 10.8 0.7 0.8 0.8 0.0 31.7 1.1 0.4 3.7 1.9 18.5 8.5 0.0 2.3 1.0 8.9 13.9 21.5 11.5 3.9 9.2 5.1 0.0 3.4 26.5 2.2 0.4 0.0 0.3 49.8 1.5 17.0 1.1 0.2 8.0 0.3 0.0 5.2 22.3 0.4 0.2 13.8 62.8 15.7 0.0 0.0 0.6 12.9 13.1 13.1 1.4 3.4 22.2 0.0 6.3 5.2 0.1 0.5 7.5 7.6 2.5 3.1 0.1 0.1 0.0 5.5 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 8.7 2.0 12.2 10.7 6.4 2.7 5.3 3.7 7.2 10.9 4.3 0.2 6.4 5.1 2.6 0.4 11.5 5.4 6.0 1.2 7.5 22.7 10.4 18.5 20.0 9.6 7.3 0.0 4.1 0.0 134.8 0.0 3.5 11.7 23.8 2.3 0.8 51.6 0.0 79.7 20.8 2.1 2.5 26.0 20.7 0.0 6.2 5.0 125.2 0.6 38.7 58.9 51.4 12.2 1.6 1.5 1.9 13.4 0.4 1.8 3.7 0.0 1.9 0.0 12.1 3.8 10.2 54.4 2.6 0.0 7.2 79.2 0.8 39.2 1.1 0.0 0.8 1.0 1.4 17.2 0.9 24.0 1.9 0.5 6.8 46.5 6.5 EPHB2 "DRT, EPHT3, ERK, Hek5, Tyro5" ENSG00000133216 "EPH receptor B2" P29323 1 22710839-22921500 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Neurogenesis "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 23.3" "Cell type enhanced" "Detected in many" "Ductal cells: 45.1;Enteroendocrine cells: 48.7;Intestinal goblet cells: 61.1;Oligodendrocytes: 76.3;Pancreatic endocrine cells: 63.7;Undifferentiated cells: 97.2" "Cancer enhanced" "Detected in many" "colorectal cancer: 23.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "GAMG: 86.5;HUVEC TERT2: 74.2;TIME: 79.2;U-251 MG: 69.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB013647, HPA071200" Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" No No 380000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "CAB013647: , HPA071200: AB_2686360" "unprognostic (2.47e-2)" "unprognostic (2.43e-2)" "prognostic favorable (4.98e-4)" "prognostic unfavorable (1.05e-5)" "unprognostic (3.99e-2)" "unprognostic (8.91e-3)" "unprognostic (1.23e-1)" "unprognostic (2.33e-3)" "unprognostic (1.56e-1)" "unprognostic (7.73e-2)" "unprognostic (1.23e-2)" "unprognostic (2.15e-2)" "unprognostic (2.16e-4)" "unprognostic (1.45e-1)" "unprognostic (8.07e-2)" "unprognostic (2.58e-1)" "unprognostic (3.46e-2)" 3.1 1.6 2.1 9.2 3.7 0.5 1.6 4.1 4.2 2.5 0.0 22.6 21.0 1.8 1.9 0.6 4.4 3.7 3.3 2.2 4.3 3.8 0.4 1.8 2.9 5.7 4.5 10.6 3.9 6.1 2.9 4.0 4.8 1.9 23.3 2.9 1.5 3.0 0.2 0.9 21.8 3.3 5.0 2.4 1.7 1.8 5.4 1.2 7.3 0.3 1.7 4.4 1.0 8.2 43.4 17.2 17.2 27.7 1.6 1.5 0.0 10.0 0.5 27.3 5.7 6.3 16.6 0.6 20.2 4.0 86.5 39.6 10.8 52.8 7.7 0.1 4.1 0.0 1.9 0.1 16.5 0.0 4.3 5.3 17.5 48.7 0.3 25.4 74.2 2.4 1.8 0.1 5.7 6.4 1.1 0.3 4.0 49.0 11.2 5.3 18.0 0.8 14.7 4.0 18.0 19.3 17.4 0.7 0.2 1.5 1.1 0.5 79.2 11.5 29.6 29.4 69.5 0.0 0.2 0.1 21.8 0.9 0.5 0.1 0.4 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.1 3.7 4.1 4.2 2.2 4.3 5.7 4.5 4.8 5.0 5.4 8.2 0.4 3.2 0.0 5.5 0.3 0.8 1.7 20.5 0.0 15.4 0.1 0.1 1.3 7.2 8.6 0.0 0.0 0.5 0.1 24.3 0.0 45.1 2.6 1.0 0.8 1.2 48.7 0.0 34.1 8.0 2.8 5.0 1.1 2.4 0.0 0.5 0.4 0.4 9.6 6.7 32.3 61.1 6.1 7.6 1.4 0.8 0.9 7.2 0.0 21.5 0.7 18.4 0.0 5.5 76.3 63.7 12.6 0.7 0.3 2.3 5.5 0.2 1.7 1.8 0.0 0.6 2.1 0.5 3.5 0.0 0.4 1.1 0.3 0.2 97.2 1.1 EPOR ENSG00000187266 "Erythropoietin receptor" P19235 19 11377207-11384342 "Cancer-related genes, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Congenital erythrocytosis, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 114.7;Hepatic stellate cells: 66.8;Hofbauer cells: 42.4" "Cancer enhanced" "Detected in all" "thyroid cancer: 20.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA077654 Supported "Nuclear speckles,Plasma membrane" "Intracellular and membrane" NA Yes "Cluster 14: Monocytes - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 2: Karpas-707 - Immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane" "Nuclear speckles" "HPA077654: " "unprognostic (9.13e-2)" "unprognostic (7.14e-2)" "unprognostic (1.45e-2)" "unprognostic (1.04e-1)" "unprognostic (1.88e-1)" "unprognostic (1.11e-1)" "unprognostic (3.70e-1)" "unprognostic (1.50e-2)" "unprognostic (5.60e-2)" "unprognostic (9.00e-2)" "prognostic favorable (3.17e-5)" "unprognostic (6.37e-3)" "unprognostic (1.59e-2)" "unprognostic (2.08e-1)" "unprognostic (2.00e-1)" "unprognostic (7.48e-2)" "unprognostic (1.01e-3)" 6.5 17.5 6.0 1.4 6.3 22.4 5.0 6.7 8.2 7.1 7.7 2.7 1.4 3.3 13.6 1.3 6.7 2.3 9.7 6.3 6.0 21.6 10.7 6.4 2.2 6.1 6.1 3.1 11.8 23.2 8.2 8.0 6.4 4.6 1.7 3.3 3.3 7.3 2.3 1.6 2.3 1.8 6.0 11.9 7.8 1.8 6.2 1.7 30.2 1.5 1.6 3.1 3.7 6.3 3.7 1.2 3.6 4.2 5.3 3.4 2.1 2.2 7.0 3.6 4.5 1.3 1.4 2.5 4.0 4.1 5.0 0.9 2.8 1.4 4.1 2.1 1.6 14.3 1.3 2.1 3.8 2.9 5.5 2.4 0.5 4.8 3.3 8.5 8.5 5.3 12.5 12.0 4.1 3.3 2.7 3.5 1.9 2.0 9.6 7.2 6.3 5.6 3.4 1.9 1.4 11.0 1.5 2.0 6.4 3.7 3.6 4.9 3.5 1.9 2.6 6.6 2.1 6.0 4.7 2.8 10.5 2.9 2.1 9.3 3.7 3.0 1.7 4.6 3.6 2.0 3.4 2.5 2.1 1.2 3.7 2.2 10.2 0.8 7.3 0.1 3.3 2.4 6.0 6.3 6.7 8.2 6.3 6.0 6.1 6.1 6.4 6.0 6.2 6.3 6.1 19.2 18.8 24.8 11.5 2.3 4.0 2.0 2.8 3.8 3.6 6.1 6.5 5.7 3.1 20.2 0.0 2.2 5.2 1.3 3.9 2.2 0.8 9.9 6.8 13.5 8.4 114.7 2.2 3.3 12.2 9.8 15.3 13.9 26.6 1.2 66.8 3.5 42.4 1.7 3.0 3.5 2.0 17.0 4.0 0.6 2.8 15.4 8.8 7.5 4.6 7.9 11.3 1.0 1.6 3.1 0.4 4.1 3.8 1.8 0.2 1.0 2.9 2.5 19.7 3.8 18.5 5.1 7.7 1.6 1.0 3.0 9.6 2.6 1.8 1.2 EQTN "AFAF, C9orf11, equatorin, SPACA8" ENSG00000120160 Equatorin Q9NQ60 9 27284654-27297150 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 37.8" "Cell type enriched" "Detected in some" 10 "Early spermatids: 739.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA015089, HPA015504" Enhanced Approved "Plasma membrane,Actin filaments" "Secreted in male reproductive system" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane, Actin filaments" "HPA015089: AB_1845795, HPA015504: AB_2067598" "unprognostic (7.83e-2)" "unprognostic (1.55e-1)" "unprognostic (5.64e-2)" "unprognostic (8.12e-3)" "unprognostic (1.34e-3)" "unprognostic (4.41e-2)" "unprognostic (3.21e-1)" "unprognostic (1.06e-1)" "unprognostic (4.32e-1)" "unprognostic (1.89e-1)" "unprognostic (5.67e-2)" "unprognostic (1.14e-1)" "unprognostic (4.59e-2)" "unprognostic (8.46e-2)" "unprognostic (3.90e-2)" "unprognostic (1.42e-1)" 0.2 0.0 0.4 0.0 1.2 0.0 0.2 0.8 0.6 0.2 0.2 0.3 0.4 0.2 0.5 0.0 0.2 0.0 0.0 0.2 0.4 0.2 0.0 0.3 0.2 1.5 0.9 0.5 0.4 0.0 0.0 0.0 1.3 0.1 0.3 0.1 0.0 0.1 0.1 0.2 0.3 0.0 0.8 0.2 0.2 37.8 1.6 0.0 0.2 0.1 0.0 0.1 0.1 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.2 0.8 0.6 0.2 0.4 1.5 0.9 1.3 0.8 1.6 2.0 0.0 0.0 0.0 1.0 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 739.3 0.2 0.2 0.2 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 67.8 5.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 2.9 0.0 0.1 0.7 0.0 0.2 0.6 0.2 0.0 0.0 0.0 0.0 0.2 16.2 2.4 0.0 0.3 0.1 0.0 0.1 0.2 0.1 ERBB2 "CD340, HER-2, HER2, NEU, NGL" ENSG00000141736 "Erb-b2 receptor tyrosine kinase 2" P04626 17 39687914-39730426 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Transcription, Transcription regulation" "Activator, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Collecting duct cells: 136.1;Distal enterocytes: 111.0;Proximal enterocytes: 121.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 5.0" "Lineage enriched" "Detected in many" 4 "T-cells: 5.0" "Group enriched" "Detected in many" 41 "OE19: 6565.0;SK-BR-3: 3115.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB000043, HPA001060, HPA001338, HPA001383, CAB020416, CAB062555" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 980000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB000043: AB_2335701, CAB020416: AB_442047, CAB062555: AB_2665610, HPA001060: AB_2666185, HPA001338: AB_2666279, HPA001383: AB_1078500" "unprognostic (1.97e-1)" "unprognostic (6.60e-3)" "unprognostic (6.21e-2)" "prognostic unfavorable (8.99e-8)" "unprognostic (2.96e-2)" "unprognostic (1.40e-2)" "unprognostic (1.97e-2)" "unprognostic (9.04e-2)" "unprognostic (1.79e-2)" "unprognostic (1.20e-3)" "prognostic unfavorable (9.17e-4)" "unprognostic (3.92e-1)" "prognostic favorable (2.41e-14)" "unprognostic (9.29e-2)" "unprognostic (1.40e-1)" "unprognostic (3.75e-2)" "unprognostic (1.96e-1)" 13.0 5.4 16.1 12.1 20.5 1.6 56.0 14.3 13.1 37.6 23.3 68.2 63.6 25.2 26.6 102.4 64.2 31.0 57.0 13.3 16.0 73.5 31.1 36.2 4.8 22.4 22.7 23.9 37.6 81.7 17.3 27.0 17.1 55.6 48.5 8.1 68.7 50.5 20.7 91.0 67.3 25.0 18.5 6.9 49.7 11.7 15.4 7.4 56.5 15.0 28.0 40.0 52.9 16.4 38.7 45.7 50.4 31.7 59.3 41.2 67.7 27.2 44.9 58.6 48.9 34.4 102.7 2.9 54.6 62.7 31.5 117.6 2.8 61.2 26.9 5.2 38.6 1.8 36.0 56.3 35.3 0.9 1.0 41.0 56.6 36.2 21.9 56.2 24.4 1.9 6.2 2.4 43.3 59.4 7.1 3.0 90.7 6565.0 11.7 3.9 20.5 5.4 58.9 118.9 9.4 2.6 51.5 3115.9 16.9 62.2 88.1 2.2 2.9 30.2 37.7 37.7 17.6 5.3 3.3 3.6 3.0 0.9 98.5 1.1 0.2 0.4 5.0 0.1 0.3 0.6 0.2 1.4 0.2 0.6 0.5 1.4 1.2 0.4 0.1 0.1 0.2 1.7 16.1 20.5 14.3 13.1 13.3 16.0 22.4 22.7 17.1 18.5 15.4 16.4 3.9 41.7 40.1 12.7 2.2 14.0 19.0 37.1 17.6 4.6 62.7 34.9 20.7 32.9 43.8 136.1 12.5 12.0 5.1 111.0 7.9 30.9 0.3 48.7 13.9 6.1 15.6 1.3 0.9 25.5 84.8 15.7 53.5 61.3 0.0 20.3 11.7 10.7 4.0 6.7 1.0 47.5 42.7 2.2 3.1 1.0 18.3 1.7 10.6 1.0 1.2 24.1 26.8 2.0 1.0 32.5 54.8 23.0 1.1 34.9 121.7 19.5 42.0 5.8 0.0 13.1 12.7 6.8 5.7 43.5 18.9 22.7 2.8 4.4 75.4 31.3 ERBB3 "HER3, LCCS2" ENSG00000065361 "Erb-b2 receptor tyrosine kinase 3" P21860 12 56076799-56103505 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 254.3;Oligodendrocytes: 187.0;Paneth cells: 184.6;Proximal enterocytes: 240.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "basophil: 2.4;neutrophil: 1.0" "Lineage enriched" "Detected in single" 6 "granulocytes: 2.4" "Cell line enhanced" "Detected in many" "Hep G2: 116.4;OE19: 119.1;RT4: 89.7;SK-BR-3: 106.5;SK-MEL-30: 149.5;T-47d: 122.2;WM-115: 153.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025331, HPA045396, HPA070524" Approved Supported "Plasma membrane,Actin filaments" "Secreted - unknown location" NA NA 450000 "Cluster 17: Basophils - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Actin filaments" "CAB025331: , HPA045396: AB_2679312, HPA070524: " "unprognostic (2.97e-1)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" "unprognostic (8.97e-2)" "unprognostic (1.63e-1)" "unprognostic (1.07e-3)" "unprognostic (2.31e-3)" "unprognostic (2.66e-2)" "unprognostic (9.89e-2)" "unprognostic (4.30e-2)" "unprognostic (4.76e-3)" "unprognostic (5.77e-2)" "unprognostic (1.06e-2)" "unprognostic (4.56e-2)" "unprognostic (1.57e-1)" "unprognostic (6.72e-3)" "unprognostic (2.07e-2)" 2.4 2.6 34.4 8.0 69.2 0.9 56.5 45.9 62.0 20.9 10.9 62.9 88.5 5.5 12.3 82.0 12.1 30.6 9.0 39.2 43.1 36.2 98.6 29.3 0.6 59.4 54.4 1.6 57.0 23.8 2.4 13.0 54.7 37.8 64.1 1.3 83.0 18.2 2.4 75.7 82.5 3.8 36.2 0.6 74.7 2.3 55.9 1.0 9.4 1.7 12.5 21.8 44.2 104.9 39.8 2.1 3.2 1.4 0.2 0.1 63.2 3.9 7.2 4.5 4.1 20.4 70.4 0.2 0.8 1.0 0.6 32.2 5.0 7.7 2.3 0.7 3.0 0.1 1.1 116.4 0.1 0.1 0.5 1.3 9.3 0.7 0.3 0.7 0.1 0.8 2.6 1.0 0.4 71.6 0.4 1.3 10.4 119.1 1.9 0.4 7.4 2.1 7.9 89.7 3.3 1.3 2.6 106.5 149.5 9.1 122.2 0.7 0.3 0.5 4.0 1.9 0.5 0.9 0.6 0.6 0.4 0.3 153.4 2.4 0.1 0.3 0.2 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.4 1.0 0.4 0.2 0.2 0.3 0.1 34.4 69.2 45.9 62.0 39.2 43.1 59.4 54.4 54.7 36.2 55.9 104.9 0.8 118.6 81.0 1.0 1.5 18.2 15.3 21.6 19.4 1.5 106.4 47.8 1.9 171.6 74.6 35.0 2.1 52.6 2.0 254.3 1.9 60.1 1.3 36.1 10.9 2.7 93.1 2.7 0.7 88.1 84.6 4.5 96.4 95.9 1.3 0.7 5.0 112.0 6.1 0.0 2.0 145.2 40.7 1.9 3.7 0.5 1.5 1.5 55.2 1.0 1.7 7.7 0.0 49.8 187.0 94.8 184.6 0.0 0.3 103.3 240.2 30.0 54.8 1.1 6.6 4.5 3.4 9.5 13.4 87.7 36.9 100.6 2.5 0.1 136.9 135.4 ERBIN "ERBB2IP, LAP2" ENSG00000112851 "Erbb2 interacting protein" Q96RT1 5 65926556-66082546 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 119.1" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 70.5;dendritic cells: 61.3;Endometrial ciliated cells: 62.3;Glandular and luminal cells: 101.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048606, HPA059863" Approved Supported "Nuclear speckles,Plasma membrane" NA NA 39000 "Cluster 38: Basophils - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 7: Non-specific - Mitochondria" "Nuclear speckles, Plasma membrane" "HPA048606: AB_2680461, HPA059863: AB_2684146" "unprognostic (4.34e-1)" "unprognostic (5.56e-2)" "unprognostic (9.88e-2)" "unprognostic (2.15e-2)" "unprognostic (2.04e-1)" "unprognostic (4.23e-3)" "unprognostic (1.74e-1)" "unprognostic (1.01e-1)" "unprognostic (1.46e-2)" "unprognostic (6.52e-2)" "unprognostic (5.45e-3)" "unprognostic (7.98e-2)" "unprognostic (5.62e-3)" "unprognostic (7.21e-3)" "unprognostic (3.08e-1)" "unprognostic (6.86e-2)" "unprognostic (7.81e-2)" 15.7 14.5 65.2 29.5 109.6 30.0 24.7 64.2 67.6 23.2 19.0 27.8 24.5 22.6 27.0 20.1 20.0 28.4 16.9 56.2 91.6 29.5 33.3 21.5 40.6 91.3 88.0 20.0 18.8 22.6 8.3 16.4 106.0 26.4 26.3 28.1 21.8 20.2 19.8 32.8 44.1 19.7 64.4 31.4 40.3 27.5 86.6 48.7 29.9 20.7 39.0 28.5 13.0 119.1 97.8 32.2 41.5 49.6 30.0 36.0 31.5 61.5 62.6 85.3 94.3 31.5 113.8 82.2 58.8 95.3 67.2 31.7 26.5 45.1 149.4 36.3 12.0 28.3 41.3 24.7 39.5 22.0 26.3 39.4 29.2 47.2 67.5 50.0 32.1 37.1 29.4 54.6 58.1 33.5 59.0 25.1 10.1 9.7 9.5 53.7 33.0 45.8 49.9 65.6 20.0 18.7 65.0 21.7 46.4 30.9 38.4 53.8 29.8 48.3 85.9 29.8 80.8 47.2 31.7 69.8 31.6 35.9 28.1 13.1 4.1 5.5 5.2 5.8 4.8 4.7 3.9 4.6 3.5 3.7 4.5 4.8 9.2 3.9 5.1 2.2 3.8 2.8 65.2 109.6 64.2 67.6 56.2 91.6 91.3 88.0 106.0 64.4 86.6 119.1 53.0 70.5 57.5 0.0 13.2 0.0 0.0 0.0 0.0 0.0 39.4 24.8 0.0 0.0 31.6 53.3 0.0 6.5 61.3 0.0 11.7 26.7 0.0 62.3 50.0 26.1 0.0 0.0 0.0 24.9 11.2 16.2 0.0 101.9 27.8 47.8 0.0 0.0 40.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.4 0.0 0.0 5.7 0.0 0.0 0.0 0.0 50.3 0.0 0.0 13.3 0.0 0.0 41.7 24.0 0.0 0.0 0.0 17.1 0.0 0.0 0.0 0.0 8.9 20.0 51.4 0.0 0.0 ERMN "ERMIN, JN, KIAA1189" ENSG00000136541 Ermin Q8TAM6 2 157318631-157327713 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 17 "brain: 498.6;choroid plexus: 136.2" "Cell type enriched" "Detected in some" 51 "Oligodendrocytes: 290.9" "Cancer enriched" "Detected in some" 4 "glioma: 9.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 7 "HAP1: 25.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038295, HPA038296" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "HPA038295: AB_10805353, HPA038296: AB_10796217" "unprognostic (7.89e-2)" "unprognostic (9.06e-3)" "unprognostic (2.71e-2)" "prognostic favorable (6.93e-6)" "unprognostic (1.06e-1)" "unprognostic (2.02e-2)" "unprognostic (9.14e-2)" "unprognostic (1.79e-1)" "unprognostic (4.57e-2)" "unprognostic (4.40e-2)" "unprognostic (1.07e-1)" "unprognostic (5.49e-2)" "unprognostic (1.46e-3)" "unprognostic (2.84e-2)" "unprognostic (7.96e-2)" "unprognostic (9.97e-3)" "unprognostic (5.76e-2)" 0.7 0.2 212.4 2.3 342.3 18.8 0.5 312.8 386.9 0.5 136.2 0.7 0.5 0.4 0.1 0.4 0.4 0.8 0.3 208.7 266.4 0.5 0.5 2.4 3.3 408.3 313.2 0.2 0.3 0.0 0.4 0.1 391.8 0.3 0.9 0.6 1.7 0.3 0.4 0.7 3.8 0.3 266.5 4.7 1.3 0.5 300.8 1.6 0.4 0.0 3.0 0.7 0.3 498.6 0.1 0.3 0.3 0.2 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.1 0.2 1.3 0.0 1.9 0.0 0.3 25.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.0 0.7 0.4 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.2 3.5 0.4 0.2 0.7 2.3 0.2 0.1 0.5 0.0 0.4 0.5 0.0 1.0 0.4 0.5 0.0 0.1 0.0 0.3 0.6 1.2 0.0 0.2 0.1 0.3 0.6 3.4 2.5 0.6 1.7 0.9 0.9 0.5 0.3 0.3 0.4 0.2 0.2 0.1 0.1 0.1 0.1 0.3 0.3 0.3 0.6 0.5 0.2 0.3 0.2 0.1 212.4 342.3 312.8 386.9 208.7 266.4 408.3 313.2 391.8 266.5 300.8 498.6 0.1 0.0 1.3 1.6 1.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.4 0.0 0.0 0.0 0.0 0.0 5.6 0.0 0.0 0.0 1.3 0.1 0.1 0.0 0.0 0.0 0.6 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.4 0.0 0.2 0.0 0.8 0.2 0.0 1.2 0.9 0.1 0.0 2.2 0.0 1.9 1.1 0.0 3.1 2.0 290.9 0.0 0.0 0.0 4.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.5 2.7 0.0 0.0 0.0 ESYT2 "CHR2SYT, FAM62B, KIAA1228" ENSG00000117868 "Extended synaptotagmin 2" A0FGR8 7 158730995-158830253 "Plasma proteins, Predicted membrane proteins, Transporters" "Endocytosis, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Microglial cells: 185.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002132, HPA070823" Approved Approved "Plasma membrane,Cytosol" NA NA 24000 "Cluster 48: NK-cells - Unknown function" "Cluster 52: Non-specific - Ribosome" "Cluster 18: U-2197 - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA002132: AB_1078807, HPA070823: " "unprognostic (2.30e-1)" "unprognostic (1.06e-2)" "unprognostic (2.72e-2)" "unprognostic (2.84e-2)" "unprognostic (5.72e-2)" "unprognostic (5.43e-2)" "unprognostic (9.01e-2)" "unprognostic (9.94e-2)" "unprognostic (1.72e-1)" "unprognostic (8.71e-3)" "prognostic unfavorable (5.73e-4)" "unprognostic (2.13e-1)" "unprognostic (7.54e-2)" "unprognostic (6.70e-2)" "unprognostic (4.58e-2)" "unprognostic (3.70e-3)" "prognostic unfavorable (2.81e-5)" 53.9 37.0 24.0 25.6 25.0 34.8 33.9 21.8 28.7 30.8 22.7 38.4 22.3 36.1 30.1 45.0 34.4 32.2 35.1 27.7 25.3 27.2 24.5 33.4 27.5 22.1 24.6 48.1 29.2 30.9 20.6 43.3 24.6 25.3 30.3 14.2 32.1 30.5 44.9 31.0 27.6 38.7 21.7 21.4 25.5 15.8 30.7 37.0 39.3 41.8 25.4 35.8 29.3 19.4 92.9 57.8 19.5 19.8 62.2 72.6 55.3 47.5 48.9 36.7 40.6 29.7 106.1 27.5 52.2 86.2 66.6 46.0 27.8 50.2 35.1 31.5 28.3 26.2 44.0 32.2 64.1 95.0 55.8 53.4 51.8 41.8 55.2 73.1 44.8 81.9 56.4 97.8 61.9 71.7 96.0 66.7 29.2 53.9 56.7 82.4 37.0 38.8 58.6 38.4 46.8 30.2 151.6 109.7 66.7 43.4 37.7 96.3 69.3 40.3 18.8 178.7 60.5 68.6 17.3 27.5 102.4 93.8 121.5 1.7 1.4 1.2 6.1 1.8 3.4 1.1 5.1 4.3 2.8 0.6 4.6 5.5 0.9 5.4 1.2 1.8 4.2 2.3 24.0 25.0 21.8 28.7 27.7 25.3 22.1 24.6 24.6 21.7 30.7 19.4 65.7 38.5 32.4 55.5 18.1 46.1 12.9 22.6 19.4 15.0 32.6 21.6 30.8 21.5 33.7 47.8 16.7 31.6 54.0 41.0 3.9 15.3 18.0 60.6 17.8 48.5 21.1 17.7 137.1 20.0 26.1 44.2 15.8 47.0 12.6 36.8 23.2 20.9 20.2 13.5 119.3 31.2 24.4 20.2 83.6 5.3 35.1 27.7 51.6 185.5 21.9 12.1 43.3 67.3 61.4 29.9 14.1 54.5 36.2 23.2 28.0 8.7 61.8 10.8 32.9 42.6 60.4 10.6 10.2 22.0 51.7 40.8 43.4 19.5 26.0 25.8 EVA1A "FAM176A, FLJ13391, TMEM166" ENSG00000115363 "Eva-1 homolog A, regulator of programmed cell death" Q9H8M9 2 75469302-75569722 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Apoptosis, Autophagy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "liver: 191.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 41.7;Cytotrophoblasts: 43.3;Hepatocytes: 78.1;Proximal tubular cells: 77.3;Syncytiotrophoblasts: 124.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 85.7;U-138 MG: 110.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA008055 Approved Supported "Vesicles,Plasma membrane" NA Yes "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Vesicles "Plasma membrane" "HPA008055: AB_1080308" "unprognostic (2.72e-1)" "unprognostic (2.61e-2)" "unprognostic (4.14e-3)" "unprognostic (1.01e-1)" "unprognostic (1.36e-2)" "unprognostic (3.60e-2)" "unprognostic (5.02e-2)" "unprognostic (1.77e-2)" "unprognostic (1.77e-1)" "prognostic favorable (5.67e-4)" "unprognostic (7.33e-2)" "unprognostic (1.22e-1)" "prognostic favorable (5.80e-4)" "unprognostic (8.19e-2)" "unprognostic (4.37e-2)" "unprognostic (2.43e-2)" "unprognostic (9.07e-2)" 1.1 0.5 0.2 1.1 0.9 0.1 3.4 0.6 0.5 9.8 0.2 0.7 1.7 2.8 9.6 0.4 3.7 1.2 1.6 0.2 0.3 20.0 191.6 20.7 0.4 1.1 0.5 0.5 23.8 7.6 1.1 17.3 0.9 0.9 0.7 0.5 8.9 2.2 1.2 2.7 1.8 2.0 0.7 10.8 0.6 2.9 0.8 5.1 1.8 1.6 0.3 0.8 0.8 0.8 1.0 14.5 1.5 0.4 3.1 21.2 1.4 68.0 45.3 59.2 30.1 0.5 1.2 0.1 6.3 85.7 54.2 9.4 1.7 14.4 36.8 0.0 1.1 0.0 2.5 45.7 2.2 0.0 0.1 15.0 8.3 73.2 33.3 59.0 37.2 0.0 0.0 0.0 46.1 0.0 0.1 0.0 3.3 0.2 23.5 7.9 0.1 0.0 32.5 0.5 0.9 1.6 6.2 0.4 53.7 2.2 0.2 0.3 31.0 110.3 46.3 2.0 71.9 0.7 0.1 0.3 62.5 0.0 59.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.9 0.6 0.5 0.2 0.3 1.1 0.5 0.9 0.7 0.8 0.8 6.1 41.7 35.4 1.0 0.9 2.8 13.7 14.3 3.4 1.2 11.7 12.3 0.3 1.5 23.0 11.0 0.0 43.3 0.4 0.1 27.4 30.5 12.2 13.3 1.4 4.8 1.8 0.0 1.1 16.1 25.9 4.7 0.0 11.4 0.0 0.0 2.2 78.1 3.5 0.0 0.9 1.1 4.1 0.8 1.2 9.4 0.3 0.6 28.4 2.8 0.1 0.0 0.0 1.5 0.9 9.7 0.0 0.7 0.0 12.3 0.5 77.3 1.7 0.1 0.0 2.2 9.0 2.2 0.9 1.1 0.9 124.8 1.1 0.0 1.6 10.5 EXOC3L1 "EXOC3L, FLJ35539, FLJ35587" ENSG00000179044 "Exocyst complex component 3 like 1" Q86VI1 16 67184379-67190185 "Predicted intracellular proteins" Exocytosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 44.7" "Cell type enhanced" "Detected in many" "Adipocytes: 26.4;Endothelial cells: 19.6;Granulosa cells: 20.8;Hepatic stellate cells: 28.9;Leydig cells: 15.5;Peritubular cells: 18.4;Theca cells: 32.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.7;HUVEC TERT2: 3.5;SCLC-21H: 6.4;SuSa: 2.1;TIME: 2.5" "Not detected" "Not detected" "Not detected" "Not detected" HPA029574 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 64: Macrophages - Immune response" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Vesicles, Plasma membrane" "HPA029574: AB_10602495" "unprognostic (1.15e-2)" "unprognostic (4.91e-2)" "unprognostic (6.87e-3)" "unprognostic (2.09e-3)" "unprognostic (2.33e-1)" "unprognostic (2.46e-2)" "unprognostic (6.77e-2)" "unprognostic (3.98e-2)" "unprognostic (1.55e-1)" "unprognostic (1.26e-2)" "unprognostic (6.48e-3)" "unprognostic (2.88e-1)" "unprognostic (6.64e-3)" "unprognostic (3.40e-1)" "unprognostic (1.23e-1)" "unprognostic (3.26e-1)" "unprognostic (1.35e-1)" 6.4 4.6 0.5 1.8 0.5 0.0 4.1 1.0 0.8 2.6 0.0 1.6 0.9 2.8 0.1 1.3 1.8 1.1 5.4 0.5 0.5 7.3 2.1 10.0 1.4 0.8 0.2 3.6 1.6 0.8 2.0 5.9 1.1 2.4 0.4 0.2 1.6 0.6 2.1 1.2 1.7 0.9 0.1 44.7 1.5 2.1 0.4 0.1 7.1 0.8 0.2 1.7 1.3 0.1 0.1 0.0 0.7 0.2 0.0 0.0 1.7 0.3 0.0 0.0 0.0 0.8 0.1 0.0 1.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.2 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 3.5 0.4 0.3 0.0 0.1 0.1 0.2 0.0 0.2 0.0 0.4 0.8 0.7 0.1 0.0 0.1 6.4 0.8 0.8 0.1 0.0 2.1 0.6 0.0 2.5 0.1 0.1 0.1 0.0 0.1 0.1 0.1 0.4 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.5 0.5 1.0 0.8 0.5 0.5 0.8 0.2 1.1 0.1 0.4 0.1 26.4 0.0 0.0 0.3 0.3 0.9 2.1 2.8 5.7 1.5 3.0 5.2 1.6 0.0 0.4 3.7 0.0 0.6 0.2 4.6 7.9 1.0 2.0 0.1 0.3 19.6 1.2 2.7 0.1 3.7 4.3 2.6 1.5 0.4 0.0 20.8 28.9 1.4 0.8 3.3 0.3 3.4 2.0 1.9 0.2 5.5 15.5 1.8 0.0 1.0 4.0 0.3 0.0 1.0 0.0 0.6 3.1 18.4 0.0 0.4 8.9 0.2 0.3 0.9 0.0 0.3 1.1 4.0 8.6 1.2 2.0 0.8 0.2 32.5 2.7 1.6 FABP5 "E-FABP, KFABP, PA-FABP" ENSG00000164687 "Fatty acid binding protein 5" Q01469 8 81280536-81284777 "Cancer-related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" Transport "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 3691.0;vagina: 2600.3" "Cell type enhanced" "Detected in all" "Adipocytes: 2511.2;Alveolar cells type 2: 1891.0;Hofbauer cells: 2385.2;Squamous epithelial cells: 9211.0" "Group enriched" "Detected in all" 4 "cervical cancer: 268.3;head and neck cancer: 288.8;urothelial cancer: 73.7" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 1167.2;MOLT-4: 1213.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017831, CAB040577, HPA051895" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 14000000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB017831: , CAB040577: , HPA051895: AB_2681654" "unprognostic (8.76e-2)" "unprognostic (7.28e-2)" "unprognostic (1.54e-2)" "unprognostic (9.04e-2)" "unprognostic (1.33e-3)" "unprognostic (1.37e-1)" "unprognostic (1.95e-3)" "unprognostic (4.03e-3)" "unprognostic (2.71e-1)" "unprognostic (3.13e-1)" "unprognostic (6.16e-2)" "unprognostic (3.57e-2)" "prognostic unfavorable (4.69e-10)" "unprognostic (1.99e-1)" "unprognostic (3.72e-1)" "unprognostic (1.61e-1)" "unprognostic (6.60e-2)" 379.8 15.5 107.9 137.8 112.9 111.8 241.8 112.3 146.5 1340.4 307.4 256.7 83.3 62.7 4.8 3691.0 22.4 87.7 343.4 116.6 130.7 34.0 27.5 272.5 191.4 162.8 120.5 12.1 73.1 443.0 32.7 338.8 155.7 22.9 210.6 33.3 514.9 17.1 119.1 692.7 122.3 52.4 133.1 127.4 181.2 45.1 118.2 137.6 74.9 306.1 292.9 362.3 2600.3 138.9 76.9 215.9 133.1 0.3 615.7 59.0 0.3 158.0 8.9 123.2 153.3 2.2 100.3 1167.2 86.7 38.3 1.1 69.2 328.9 254.8 103.7 597.6 603.2 449.0 136.2 345.0 54.2 421.6 107.9 45.0 507.0 146.8 306.1 121.3 708.9 328.6 125.9 124.1 73.7 69.3 1213.7 199.9 170.5 785.1 732.1 526.0 0.4 127.7 198.9 951.4 514.4 190.7 74.1 24.7 61.0 230.2 1.2 201.6 97.0 0.1 331.3 1.6 1.4 155.6 70.1 902.2 52.2 396.8 184.9 8.1 14.3 0.9 6.1 16.6 9.3 17.2 6.9 13.7 55.9 10.4 3.1 11.9 5.2 22.3 5.5 54.8 9.8 13.4 107.9 112.9 112.3 146.5 116.6 130.7 162.8 120.5 155.7 133.1 118.2 138.9 2511.2 288.4 1891.0 30.7 93.0 121.0 90.0 881.2 727.3 23.7 22.3 48.6 5.7 2.8 649.8 22.0 45.9 28.0 97.5 420.3 3.9 35.4 29.5 55.7 579.5 662.2 197.2 74.4 7.7 23.8 272.4 140.6 278.8 29.6 55.8 70.1 35.3 1.4 2385.2 21.9 10.9 216.3 175.0 182.2 764.3 46.0 6.2 405.5 206.3 4.7 697.1 273.0 15.5 6.0 16.3 43.3 561.0 5.3 132.9 71.3 10.4 2.3 115.7 43.5 361.6 140.0 336.8 179.4 182.5 9211.0 168.6 27.0 102.3 68.8 419.2 232.6 FAIM "FAIM1, FLJ10582" ENSG00000158234 "Fas apoptotic inhibitory molecule" Q9NVQ4 3 138608606-138633376 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "retina: 235.0" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 173.3;Rod photoreceptor cells: 228.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "U-698: 135.7" "Low region specificity" "Detected in all" "HPA042440, HPA052209" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA042440: AB_2677999, HPA052209: AB_2681761" "unprognostic (6.45e-2)" "unprognostic (8.21e-3)" "unprognostic (5.97e-2)" "unprognostic (1.11e-1)" "unprognostic (3.24e-1)" "unprognostic (8.31e-2)" "prognostic unfavorable (3.96e-5)" "unprognostic (4.84e-2)" "unprognostic (4.15e-2)" "unprognostic (9.23e-3)" "unprognostic (2.29e-1)" "unprognostic (2.63e-2)" "prognostic favorable (6.63e-4)" "unprognostic (4.76e-2)" "unprognostic (3.51e-1)" "unprognostic (3.43e-1)" "unprognostic (6.98e-2)" 18.3 8.6 16.8 6.9 17.9 4.1 15.6 17.5 21.3 31.7 14.9 9.3 6.4 12.6 19.5 12.2 38.2 12.1 6.4 16.2 18.6 15.3 8.2 10.5 10.8 18.9 17.7 10.8 38.1 8.5 10.4 8.4 19.4 14.9 7.9 235.0 9.6 21.7 5.4 8.5 6.1 9.7 19.2 4.9 9.8 7.3 17.1 19.8 20.3 5.5 13.7 13.5 10.4 19.9 80.8 15.5 1.7 13.9 14.7 27.2 55.4 24.4 14.7 25.2 21.5 26.8 23.2 0.2 21.0 32.0 29.0 20.9 66.8 13.9 28.2 66.2 69.8 15.1 42.9 39.1 16.3 0.0 4.8 38.4 26.5 9.4 14.4 15.4 27.5 5.7 10.0 20.0 15.8 30.7 0.4 68.3 30.1 2.5 15.3 81.4 18.0 2.1 40.4 39.5 26.0 22.1 43.2 23.8 64.6 16.4 40.1 20.0 16.9 5.1 11.9 25.9 12.0 0.0 0.4 135.7 20.8 0.2 21.0 16.8 2.9 2.2 10.5 3.3 9.6 17.0 5.8 8.4 6.3 12.0 3.8 9.8 0.4 18.8 2.2 4.3 6.9 4.3 16.8 17.9 17.5 21.3 16.2 18.6 18.9 17.7 19.4 19.2 17.1 19.9 16.4 19.2 22.9 9.1 12.7 10.8 30.3 35.2 14.2 31.9 14.3 21.5 5.3 68.6 32.4 25.8 66.7 42.0 14.7 5.9 31.3 63.1 12.0 173.3 29.8 14.5 21.1 7.2 7.7 50.0 33.3 16.8 8.2 41.3 41.2 17.2 8.9 9.4 25.2 15.2 6.1 8.8 14.2 3.2 5.7 16.5 17.4 6.5 16.0 1.9 15.6 45.3 21.6 11.1 16.5 31.3 4.4 19.9 14.2 22.1 2.2 28.1 77.5 228.3 0.0 25.0 22.6 14.1 4.2 16.6 13.1 14.6 10.8 14.6 11.7 21.6 FAM126A "DRCTNNB1A, HCC, HYCC1, hyccin" ENSG00000122591 "Family with sequence similarity 126 member A" Q9BYI3 7 22889371-23014130 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cataract, Disease variant, Leukodystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocytes: 133.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042873 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042873: AB_2678207" "unprognostic (7.94e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-3)" "unprognostic (1.02e-1)" "unprognostic (1.96e-1)" "unprognostic (7.38e-2)" "unprognostic (3.54e-4)" "unprognostic (1.35e-1)" "unprognostic (9.76e-3)" "unprognostic (1.30e-2)" "unprognostic (7.23e-2)" "unprognostic (6.19e-2)" "prognostic unfavorable (6.04e-7)" "prognostic unfavorable (5.99e-4)" "unprognostic (1.87e-1)" "unprognostic (2.40e-2)" "prognostic unfavorable (9.03e-4)" 14.9 4.7 5.0 8.5 6.9 4.2 12.2 4.4 6.5 9.7 7.9 9.7 9.4 8.7 1.4 12.2 6.7 11.4 10.5 12.1 4.5 4.7 8.5 13.7 11.5 5.0 5.9 6.6 6.2 2.3 5.0 14.8 5.4 5.9 4.4 4.9 6.8 4.8 25.0 4.9 6.9 11.5 4.5 11.8 4.6 12.0 6.3 4.2 6.6 15.3 9.2 9.4 11.2 7.8 22.4 12.4 63.6 22.3 61.3 100.9 10.6 103.0 101.8 41.6 63.9 19.8 10.6 13.3 15.9 82.6 87.2 7.7 44.3 14.7 72.6 6.6 22.4 14.7 18.1 13.0 48.0 19.3 15.7 41.1 9.2 85.0 61.3 83.4 42.5 7.5 30.4 58.6 77.5 7.9 10.8 24.2 63.0 0.1 22.9 15.7 63.5 9.5 13.1 11.2 10.4 0.1 38.1 0.4 19.2 52.5 8.2 20.4 51.0 150.0 18.3 71.8 37.4 67.2 30.6 60.9 91.1 12.5 112.6 4.7 2.9 13.7 1.4 7.8 1.3 6.4 2.6 1.3 3.9 7.4 0.9 1.5 0.3 2.1 9.8 1.6 4.0 2.5 5.0 6.9 4.4 6.5 12.1 4.5 5.0 5.9 5.4 4.5 6.3 7.8 27.8 3.2 15.1 19.6 29.1 25.5 5.1 8.3 15.9 60.3 5.4 32.4 21.9 2.8 4.2 3.7 2.1 11.8 28.8 0.5 0.0 6.8 49.0 12.5 22.4 31.4 7.7 19.8 13.6 4.8 15.5 42.9 2.6 11.3 8.2 8.6 26.0 17.7 15.2 16.8 13.6 3.0 2.0 25.1 55.2 22.4 20.2 31.5 35.6 47.8 24.0 6.8 11.3 23.6 133.2 3.6 1.4 19.5 26.4 4.7 8.3 5.7 2.4 4.6 19.7 24.0 31.7 72.2 11.1 35.0 24.0 6.0 20.6 12.2 4.7 6.5 FAM171A1 "APCN, C10orf38, FLJ12884" ENSG00000148468 "Family with sequence similarity 171 member A1" Q5VUB5 10 15211643-15371289 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 86.7" "Cell type enhanced" "Detected in many" "Astrocytes: 263.8;Cholangiocytes: 98.7;Excitatory neurons: 166.9;Oligodendrocytes: 214.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "gdT-cell: 1.7;MAIT T-cell: 4.4;memory CD4 T-cell: 2.5;memory CD8 T-cell: 2.2;naive CD4 T-cell: 4.7;naive CD8 T-cell: 2.4" "Lineage enriched" "Detected in single" 19 "T-cells: 4.7" "Cell line enhanced" "Detected in many" "TIME: 105.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051345 Approved Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" Nucleoplasm "HPA051345: AB_2681449" "unprognostic (3.60e-2)" "unprognostic (7.15e-2)" "unprognostic (2.21e-1)" "unprognostic (5.28e-2)" "unprognostic (1.57e-1)" "unprognostic (4.11e-2)" "unprognostic (9.84e-2)" "unprognostic (9.19e-2)" "unprognostic (2.28e-1)" "unprognostic (3.97e-2)" "unprognostic (3.09e-2)" "unprognostic (1.87e-1)" "prognostic favorable (2.71e-5)" "unprognostic (3.08e-1)" "unprognostic (1.86e-1)" "prognostic unfavorable (4.90e-6)" "unprognostic (3.28e-2)" 11.0 5.0 60.1 7.5 73.2 0.5 8.8 69.8 56.4 11.8 22.7 21.6 19.1 12.8 6.4 6.4 15.6 12.9 10.6 68.5 49.5 31.9 15.4 7.4 6.0 79.6 64.8 14.2 22.4 10.9 3.7 4.1 75.6 11.2 17.6 2.6 14.1 11.9 7.6 4.2 13.0 12.3 59.3 12.4 13.3 3.5 68.7 3.9 6.9 6.1 6.6 9.0 6.3 86.7 0.0 16.2 33.3 12.6 13.2 24.9 0.4 19.5 3.9 10.2 8.8 3.0 19.2 0.1 21.5 53.4 22.7 1.4 24.0 0.2 11.5 5.9 33.4 46.7 5.2 48.1 14.3 0.0 36.0 19.7 4.9 27.8 4.0 36.8 51.4 6.8 17.5 0.2 32.8 1.4 7.7 0.1 30.4 9.3 7.8 30.4 17.0 5.1 12.7 0.0 22.4 27.6 10.9 0.2 0.1 35.0 0.2 0.6 105.6 13.9 53.6 50.4 20.8 6.3 2.1 0.1 30.3 0.0 10.8 0.0 0.0 0.0 1.7 0.0 4.4 0.0 2.5 2.2 0.0 0.0 4.7 2.4 0.0 0.2 0.0 0.0 0.5 0.9 60.1 73.2 69.8 56.4 68.5 49.5 79.6 64.8 75.6 59.3 68.7 86.7 11.1 0.0 0.0 263.8 1.0 1.3 4.0 3.1 8.0 4.0 7.6 5.7 6.8 98.7 1.7 14.7 0.0 0.1 0.2 25.4 3.9 21.1 0.7 5.9 12.5 43.7 21.0 6.5 166.9 12.2 0.2 12.3 35.7 14.6 1.3 14.4 49.2 24.7 0.4 6.7 76.6 23.7 4.1 2.8 1.7 1.1 5.3 0.3 1.8 33.7 0.7 1.5 0.0 44.2 214.4 17.5 16.1 5.7 5.2 16.5 7.3 4.5 2.4 1.1 0.0 7.5 5.9 2.3 5.7 8.0 1.8 0.1 2.0 11.4 38.8 3.6 FAM193A "C4orf8, RES4-22" ENSG00000125386 "Family with sequence similarity 193 member A" P78312 4 2536647-2732573 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Inhibitory neurons: 70.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043116 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 71: Testis - DNA repair" "Cluster 24: NB-4 - Immune response" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA043116: AB_10795767" "unprognostic (1.56e-1)" "unprognostic (1.95e-1)" "unprognostic (2.54e-1)" "unprognostic (1.17e-3)" "unprognostic (1.97e-1)" "unprognostic (3.66e-3)" "unprognostic (6.34e-3)" "unprognostic (1.02e-1)" "unprognostic (7.16e-2)" "unprognostic (4.84e-1)" "prognostic favorable (4.80e-4)" "unprognostic (1.38e-2)" "unprognostic (2.15e-1)" "unprognostic (5.58e-2)" "unprognostic (3.47e-2)" "unprognostic (5.55e-2)" "unprognostic (4.96e-3)" 14.3 11.7 9.7 7.6 9.3 13.0 13.2 15.1 11.5 14.8 9.6 13.4 7.9 13.8 6.8 9.6 12.9 6.0 9.7 9.5 9.7 11.9 11.6 10.1 9.6 9.8 9.0 15.0 11.1 9.2 15.5 7.6 9.3 12.1 6.0 8.9 10.1 7.0 15.1 13.2 12.3 8.0 6.9 12.0 10.5 21.1 10.5 12.4 12.2 8.7 6.7 11.5 11.2 11.8 8.7 10.7 20.0 11.3 12.0 12.2 10.5 13.1 11.3 12.7 10.8 10.9 13.9 17.1 7.7 14.7 15.7 7.4 14.0 9.4 10.8 10.3 8.9 25.7 14.3 11.5 14.4 15.8 17.2 13.3 9.8 12.7 13.0 11.6 12.8 10.0 18.2 18.5 10.8 9.4 25.5 25.6 15.9 8.9 11.8 24.7 10.3 8.4 8.7 11.1 17.1 14.6 11.2 7.8 11.3 10.9 14.3 15.9 17.4 19.2 11.3 10.5 17.5 18.0 14.5 16.1 10.7 12.8 13.8 3.3 0.9 0.8 0.8 0.6 0.6 0.6 0.7 1.2 0.6 0.9 0.7 1.1 1.8 1.3 3.1 1.7 0.6 0.5 9.7 9.3 15.1 11.5 9.5 9.7 9.8 9.0 9.3 6.9 10.5 11.8 21.8 12.8 18.2 62.7 11.2 9.4 6.7 6.5 9.1 25.7 10.5 9.0 14.7 4.3 15.6 1.8 47.9 7.3 20.0 12.9 1.9 9.4 8.9 19.8 21.8 19.4 14.4 17.9 62.4 7.5 7.1 13.2 15.8 27.1 8.8 30.2 11.0 6.3 8.7 15.2 70.8 11.1 8.2 7.6 11.6 13.4 17.1 15.9 14.2 51.5 11.1 15.8 11.3 45.8 58.3 10.1 11.0 14.7 12.4 11.3 11.4 2.8 5.6 26.2 6.6 20.5 17.5 36.2 32.4 9.6 9.9 5.6 14.4 13.6 9.6 9.2 FAM205A C9orf144B ENSG00000205108 "Family with sequence similarity 205 member A" Q6ZU69 9 34723053-34729488 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in single" 96 "testis: 24.8" "Cell type enriched" "Detected in some" 5 "Early spermatids: 135.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA071267 Enhanced Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" "Nucleoli fibrillar center" "HPA071267: AB_2686376" "unprognostic (2.25e-1)" "unprognostic (3.66e-3)" "unprognostic (6.29e-3)" "unprognostic (1.90e-1)" "unprognostic (2.73e-3)" "unprognostic (7.82e-2)" "unprognostic (9.61e-2)" "unprognostic (6.41e-2)" "unprognostic (4.78e-1)" "unprognostic (7.34e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 24.8 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 135.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.6 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FAM209A "C20orf106, dJ1153D9.3" ENSG00000124103 "Family with sequence similarity 209 member A" Q5JX71 20 56517187-56526152 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 104.2" "Cell type enriched" "Detected in some" 8 "Early spermatids: 2173.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HMC-1: 2.5;Karpas-707: 1.0;U-266/84: 1.5" HPA079442 Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 37: B-cells - Transcription" "Cluster 83: Testis - Spermatogenesis" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cell Junctions" "HPA079442: " "unprognostic (1.03e-1)" "unprognostic (1.01e-2)" "unprognostic (2.19e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" "unprognostic (8.58e-3)" "unprognostic (1.06e-2)" "unprognostic (2.12e-1)" "unprognostic (2.10e-1)" "unprognostic (9.83e-2)" "unprognostic (5.56e-3)" "unprognostic (7.68e-2)" "unprognostic (1.86e-9)" "unprognostic (2.98e-2)" "unprognostic (2.07e-1)" "unprognostic (1.34e-1)" "unprognostic (3.22e-2)" 0.6 0.2 0.1 0.9 0.1 16.6 0.5 0.1 0.3 0.4 0.0 0.5 0.3 0.3 0.4 0.3 0.4 0.5 0.2 0.1 0.1 0.3 0.6 0.8 1.5 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.1 0.6 0.4 0.1 0.5 0.3 0.2 1.2 1.1 0.2 0.0 2.3 0.5 104.2 0.1 0.2 0.3 0.0 1.3 0.3 0.4 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.8 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.3 0.0 0.3 0.0 0.4 2.5 0.0 0.7 0.0 0.1 0.1 0.1 0.5 0.0 1.0 0.0 0.4 0.1 0.7 0.0 0.0 0.1 0.2 0.3 0.2 0.0 0.4 0.1 0.0 0.0 0.8 0.1 0.0 0.1 0.5 0.0 0.0 0.1 0.2 0.1 0.5 1.5 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.1 0.1 0.1 0.1 0.1 0.0 0.1 0.1 0.3 0.0 2.3 0.0 0.4 0.1 0.2 0.1 0.0 0.0 0.2 0.3 0.7 0.0 0.7 0.0 0.0 0.1 2.0 0.4 0.0 0.0 2173.4 0.2 0.2 1.1 1.2 0.4 0.0 0.0 0.2 0.2 0.0 0.5 1.3 0.1 1.1 0.2 0.1 0.0 0.0 0.2 0.0 0.6 0.0 266.1 8.7 1.2 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.4 0.0 6.4 0.0 0.1 0.2 0.0 0.8 0.0 0.0 0.3 0.2 10.4 5.9 0.1 0.0 0.3 0.5 0.1 0.1 0.2 FAM210B "C20orf108, dJ1167H4.1, DKFZP434A1114" ENSG00000124098 "Family with sequence similarity 210 member B" Q96KR6 20 56358974-56368663 "Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Erythrocyte maturation" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Erythroid cells: 449.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "SK-MEL-30: 299.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042652 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 52: Eosinophils - Transcription" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA042652: AB_2678098" "unprognostic (3.29e-1)" "prognostic favorable (5.44e-4)" "unprognostic (3.24e-2)" "unprognostic (1.66e-3)" "unprognostic (1.26e-1)" "unprognostic (3.34e-2)" "unprognostic (9.45e-2)" "prognostic favorable (4.26e-4)" "unprognostic (1.77e-1)" "unprognostic (2.24e-2)" "unprognostic (7.60e-2)" "unprognostic (2.90e-1)" "prognostic favorable (1.44e-10)" "unprognostic (1.08e-1)" "unprognostic (3.27e-2)" "unprognostic (1.84e-1)" "unprognostic (3.00e-1)" 38.2 87.6 32.1 13.9 34.1 85.2 62.0 30.0 33.6 43.7 37.7 39.8 24.7 36.5 45.7 31.1 40.1 40.6 43.9 33.9 32.6 34.6 100.3 28.2 13.9 29.6 33.8 108.9 41.5 32.7 28.1 36.7 29.9 66.8 30.6 30.0 54.9 58.7 75.2 36.5 23.3 34.2 29.6 19.6 34.2 14.1 35.9 20.6 28.4 102.2 20.0 32.5 32.7 29.1 19.9 7.5 29.3 71.6 83.2 93.4 57.1 23.8 53.4 42.6 48.7 13.9 9.6 1.6 12.1 40.9 24.6 56.2 15.9 68.7 71.0 2.9 24.9 12.2 16.9 132.0 54.4 1.3 7.4 80.2 75.2 24.1 34.0 49.3 69.4 10.2 93.6 12.7 52.7 20.6 10.4 5.4 24.9 29.0 46.7 0.1 60.4 15.9 21.9 22.9 40.4 72.9 57.9 124.6 299.1 62.3 55.0 11.1 48.4 37.8 25.2 61.0 14.7 9.9 10.9 0.4 30.0 7.7 25.2 2.3 2.3 6.9 1.7 3.3 1.3 1.1 1.9 2.3 1.7 1.3 2.0 1.9 1.0 1.4 1.5 1.5 2.3 1.0 32.1 34.1 30.0 33.6 33.9 32.6 29.6 33.8 29.9 29.6 35.9 29.1 30.3 16.0 29.3 4.2 7.4 24.9 85.4 28.2 70.6 10.3 57.5 98.8 56.8 54.3 19.3 16.5 39.6 77.7 13.5 23.8 64.6 27.9 1.0 41.4 49.0 28.8 50.9 449.3 5.7 19.5 26.3 46.1 44.9 37.4 19.1 47.5 46.1 154.5 28.0 1.7 6.6 28.6 20.3 44.1 21.2 4.7 66.8 26.2 37.4 5.6 36.6 27.8 14.4 4.0 8.4 35.7 15.3 155.7 9.4 48.7 34.1 46.1 15.6 19.2 19.7 28.1 37.1 1.1 9.4 68.6 32.5 41.9 14.6 123.4 33.4 56.3 FAM47E "FLJ42946, LOC100129583" ENSG00000189157 "Family with sequence similarity 47 member E" Q6ZV65 4 76214040-76283783 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 47.3;Endometrial ciliated cells: 34.0;Respiratory ciliated cells: 91.4" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "naive B-cell: 1.3" "Low lineage specificity" "Detected in single" "Cell line enriched" "Detected in many" 5 "OE19: 28.0" HPA053331 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 21: OE19 - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (1.59e-1)" "unprognostic (1.76e-2)" "unprognostic (3.68e-2)" "unprognostic (3.90e-4)" "unprognostic (1.37e-2)" "unprognostic (1.66e-1)" "unprognostic (1.04e-1)" "unprognostic (5.63e-2)" "unprognostic (1.06e-1)" "unprognostic (2.21e-2)" "unprognostic (3.73e-2)" "unprognostic (1.31e-1)" "unprognostic (2.16e-8)" "unprognostic (1.01e-1)" "unprognostic (1.84e-2)" "unprognostic (3.04e-2)" "unprognostic (3.01e-2)" 6.2 4.9 7.6 0.4 8.3 1.0 6.8 7.5 8.8 2.9 7.9 2.6 3.2 1.7 11.0 1.3 19.6 4.0 1.9 8.0 8.4 7.3 9.1 4.0 0.5 8.1 8.5 0.8 9.1 7.6 8.5 1.5 7.8 4.2 2.9 8.8 4.4 2.7 6.4 1.3 3.5 1.1 7.8 1.2 5.1 8.0 9.5 0.7 9.7 3.2 0.4 1.9 0.7 9.1 0.6 2.1 2.1 0.6 1.6 0.2 0.5 0.2 2.0 0.4 0.4 2.6 2.2 0.1 0.6 0.7 4.5 0.6 0.9 0.5 0.7 2.1 0.1 0.1 1.3 3.6 0.9 0.5 0.3 1.0 0.5 0.6 0.5 0.9 0.2 0.3 0.2 1.5 0.6 3.1 0.2 0.2 0.4 28.0 1.0 0.3 0.5 0.3 3.4 1.8 3.7 2.9 1.0 1.6 0.3 0.5 1.7 0.2 0.5 0.4 0.5 1.2 0.5 5.5 1.2 0.1 1.6 0.2 0.8 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.1 0.0 0.0 0.0 0.1 0.6 0.0 0.0 7.6 8.3 7.5 8.8 8.0 8.4 8.1 8.5 7.8 7.8 9.5 9.1 1.6 9.6 2.6 4.2 0.4 0.6 2.5 5.1 0.0 12.9 7.7 9.1 7.9 8.6 8.4 0.0 12.5 3.3 0.1 6.2 9.8 7.5 47.3 34.0 0.6 1.8 7.7 0.8 1.0 7.8 1.6 1.5 3.1 2.0 0.0 1.5 1.8 3.6 0.8 1.7 1.1 5.7 14.2 1.0 0.0 6.2 0.6 0.7 1.8 1.0 0.0 4.7 0.0 0.0 2.9 5.8 3.0 0.4 0.4 2.8 13.0 10.3 91.4 7.4 0.0 2.0 2.2 8.8 4.3 0.3 0.3 3.4 0.2 0.8 3.1 1.9 FAM47E-STBD1 ENSG00000272414 "FAM47E-STBD1 readthrough" 4 76251721-76311129 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "liver: 41.5;skeletal muscle: 55.9" "Group enriched" "Detected in some" 5 "Alveolar cells type 1: 6.4;Alveolar cells type 2: 1.7;Astrocytes: 2.0;Excitatory neurons: 5.1;Inhibitory neurons: 2.8;Oligodendrocyte precursor cells: 2.5;Oligodendrocytes: 3.4;Respiratory ciliated cells: 3.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 1.3;OE19: 2.7" HPA053331 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 21: OE19 - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA053331: AB_2682115" "unprognostic (3.52e-3)" "unprognostic (3.44e-1)" "unprognostic (1.53e-1)" "unprognostic (8.98e-2)" "unprognostic (5.45e-2)" "unprognostic (2.66e-1)" "unprognostic (1.99e-1)" "unprognostic (2.51e-2)" "unprognostic (1.91e-1)" "unprognostic (6.92e-6)" "unprognostic (5.59e-2)" "unprognostic (1.52e-1)" "unprognostic (3.77e-1)" 12.5 1.3 1.5 0.4 1.6 1.0 9.3 1.1 2.5 2.0 1.1 9.0 0.1 2.4 1.3 1.6 2.1 0.6 21.2 1.4 2.0 2.4 41.5 8.3 0.4 1.9 1.5 0.9 2.3 0.5 0.7 0.6 1.7 4.3 0.4 1.8 2.3 0.5 55.9 0.9 12.4 0.7 1.6 0.9 2.9 2.3 1.9 0.1 1.3 0.5 0.1 6.7 2.0 2.0 0.1 0.0 0.1 0.1 0.4 0.1 0.2 0.0 0.2 0.0 0.0 1.3 0.0 0.1 0.2 0.0 0.6 0.1 0.0 0.0 0.3 0.1 0.0 0.3 0.1 0.0 0.0 0.4 0.9 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.1 0.4 0.0 0.1 0.1 2.7 0.4 0.0 0.0 0.4 0.0 0.6 0.7 0.5 0.1 0.1 0.0 0.2 0.0 0.3 0.3 0.1 0.3 0.1 0.2 0.4 0.3 0.0 0.7 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 0.1 0.0 0.1 0.1 0.0 1.5 1.6 1.1 2.5 1.4 2.0 1.9 1.5 1.7 1.6 1.9 2.0 0.0 6.4 1.7 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FASN "FAS, SDR27X1" ENSG00000169710 "Fatty acid synthase" P49327 17 82078338-82098294 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Fatty acid biosynthesis, Fatty acid metabolism, Lipid biosynthesis, Lipid metabolism" "Hydrolase, Lyase, Multifunctional enzyme, Oxidoreductase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 372.8;breast: 271.6" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 126.0;Breast glandular cells: 442.9;Breast myoepithelial cells: 165.4;Hepatocytes: 244.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SK-BR-3: 1109.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005192, HPA006461, CAB015417, HPA056108" Enhanced Enhanced "Plasma membrane,Cytosol" No No 3400000 "Cluster 57: Non-specific - Angiogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "CAB005192: AB_2101095, CAB015417: AB_2231427, HPA006461: AB_1848437, HPA056108: AB_2683039" "unprognostic (3.35e-2)" "prognostic unfavorable (1.42e-5)" "unprognostic (9.69e-3)" "unprognostic (4.09e-2)" "unprognostic (3.46e-3)" "unprognostic (1.55e-2)" "unprognostic (3.09e-2)" "unprognostic (4.74e-3)" "unprognostic (3.15e-1)" "unprognostic (3.15e-1)" "unprognostic (2.87e-3)" "unprognostic (1.05e-1)" "prognostic unfavorable (7.16e-5)" "unprognostic (4.50e-2)" "unprognostic (9.62e-2)" "unprognostic (1.35e-2)" "unprognostic (7.03e-3)" 372.8 30.9 25.0 14.9 44.2 18.7 271.6 67.3 49.9 31.7 0.0 25.5 11.5 18.0 6.2 63.6 15.2 6.6 21.9 39.9 15.0 11.8 191.4 54.1 7.2 84.4 75.7 16.3 18.6 8.5 72.4 12.1 101.7 69.0 3.0 4.3 38.3 14.3 27.9 89.4 28.8 5.3 12.5 8.8 63.6 11.9 33.7 9.6 21.2 2.3 3.0 27.0 31.8 60.8 179.1 182.0 81.7 56.7 130.1 87.2 176.9 34.3 43.3 35.5 64.6 190.6 116.7 58.8 29.2 26.3 99.5 144.0 79.2 157.8 6.5 30.0 358.0 123.9 140.0 257.2 36.8 67.5 19.2 84.2 40.4 90.8 21.0 12.1 40.1 54.8 193.2 50.7 12.6 304.1 78.9 105.5 161.1 28.1 107.1 64.1 47.8 116.5 40.3 220.7 205.0 117.0 50.6 1109.2 93.6 29.5 199.4 123.4 71.1 52.3 107.0 45.2 88.4 68.5 17.1 60.6 31.2 71.1 79.5 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.1 25.0 44.2 67.3 49.9 39.9 15.0 84.4 75.7 101.7 12.5 33.7 60.8 9.6 25.6 126.0 28.4 7.4 7.8 12.7 33.2 8.0 28.7 442.9 165.4 5.9 21.5 28.4 11.0 6.2 32.0 12.8 35.7 3.9 19.2 1.5 19.6 19.8 10.8 18.1 20.6 11.9 29.2 77.7 13.4 33.6 17.1 12.7 29.9 10.8 244.1 13.9 30.3 12.5 22.3 22.4 9.8 6.2 3.4 16.4 7.0 17.8 4.7 6.2 14.1 8.2 11.6 17.6 19.1 23.6 11.3 9.7 60.4 6.5 5.9 23.7 13.1 0.0 9.0 14.9 1.8 11.7 34.1 13.8 29.6 10.6 27.9 27.4 19.6 FBLN7 "FLJ37440, TM14" ENSG00000144152 "Fibulin 7" Q53RD9 2 112138385-112188218 "Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" Heparin-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 14.4;Fibroblasts: 16.6;Inhibitory neurons: 30.7;Melanocytes: 17.8;Skeletal myocytes: 19.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 26 "memory CD4 T-cell: 34.4;naive CD4 T-cell: 29.5;T-reg: 36.5" "Lineage enriched" "Detected in many" 35 "T-cells: 36.5" "Cell line enhanced" "Detected in many" "AF22: 24.5;BJ hTERT+: 17.7;hTERT-RPE1: 12.8;SCLC-21H: 15.8;SH-SY5Y: 12.6;U-2197: 25.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034992 Approved "Plasma membrane,Cell Junctions" "Secreted to extracellular matrix" NA NA 310000 "Cluster 20: T-cells - T-cell receptor" "Cluster 34: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Cell Junctions" "HPA034992: AB_10601469" "unprognostic (1.72e-1)" "unprognostic (1.47e-1)" "unprognostic (5.88e-2)" "unprognostic (4.88e-3)" "unprognostic (1.24e-1)" "unprognostic (1.70e-3)" "unprognostic (4.34e-2)" "unprognostic (4.80e-2)" "unprognostic (5.77e-2)" "unprognostic (2.01e-1)" "unprognostic (7.91e-2)" "unprognostic (2.02e-2)" "unprognostic (2.35e-2)" "unprognostic (3.11e-2)" "unprognostic (8.10e-2)" "unprognostic (1.21e-2)" "unprognostic (9.33e-2)" 6.5 4.0 0.8 4.3 0.6 0.7 7.8 4.0 6.4 10.3 0.4 1.8 1.1 4.8 2.8 1.9 7.1 3.4 2.5 2.1 3.8 1.5 5.2 2.7 9.8 9.2 4.4 1.4 2.4 6.9 12.2 3.2 9.7 3.3 1.3 2.5 2.5 3.1 1.4 5.5 2.9 2.2 2.2 5.6 3.0 0.5 4.1 8.6 10.7 2.5 6.0 2.5 7.5 1.1 0.0 0.1 24.5 0.0 2.6 1.9 0.1 5.5 17.7 5.9 9.2 0.0 0.2 0.0 0.1 8.3 1.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 1.9 1.1 1.2 0.0 0.0 1.9 0.1 9.9 0.0 12.8 1.4 0.3 0.0 0.0 2.1 0.0 0.7 0.1 0.6 0.0 0.5 0.0 0.0 6.6 0.3 0.0 15.8 12.6 0.1 0.1 0.7 0.1 0.7 0.2 5.2 0.8 0.7 25.4 0.8 0.0 0.0 0.0 0.8 0.0 2.1 0.0 0.0 0.0 0.4 0.0 1.3 0.0 34.4 0.4 0.0 0.0 29.5 1.0 0.0 0.0 0.0 1.0 36.5 6.2 0.8 0.6 4.0 6.4 2.1 3.8 9.2 4.4 9.7 2.2 4.1 1.1 1.4 3.2 0.5 0.3 0.7 4.5 1.0 0.3 0.0 3.8 1.0 2.4 1.1 0.0 0.0 0.0 0.0 4.0 0.2 0.0 0.0 0.3 1.7 1.2 5.9 2.6 0.0 0.0 14.4 0.2 10.1 16.6 0.0 1.2 1.3 0.7 0.4 2.2 0.5 3.3 30.7 0.0 0.0 0.0 4.0 3.6 0.3 0.4 17.8 1.9 0.0 2.3 0.0 6.6 0.9 0.6 0.0 5.3 0.1 0.4 0.1 0.5 0.3 7.6 6.6 19.3 7.8 0.1 0.4 0.1 3.8 1.5 7.7 0.2 0.0 0.3 FBP2 ENSG00000130957 "Fructose-bisphosphatase 2" O00757 9 94558720-94593824 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Carbohydrate metabolism, Gluconeogenesis" "Allosteric enzyme, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 8 "skeletal muscle: 753.6;tongue: 385.3" "Group enriched" "Detected in some" 7 "Gastric mucus-secreting cells: 11.2;Skeletal myocytes: 8.7;Spermatogonia: 8.5" "Cancer enhanced" "Detected in some" "stomach cancer: 1.2" "Region enriched" "Detected in some" 4 "hippocampal formation: 6.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 3.9;CACO-2: 2.1;HMC-1: 2.2;MCF7: 3.0;OE19: 2.9;PC-3: 2.0;SiHa: 2.8" "Not detected" "Not detected" "Not detected" "Not detected" "HPA012513, HPA077371" Enhanced Approved "Plasma membrane,Cytosol" NA NA 960000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 28: BEWO - Transcription regulation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA012513: AB_1848446, HPA077371: " "unprognostic (3.88e-2)" "unprognostic (3.54e-4)" "unprognostic (2.38e-1)" "unprognostic (6.03e-2)" "unprognostic (2.21e-1)" "unprognostic (1.54e-2)" "unprognostic (9.40e-4)" "unprognostic (3.95e-3)" "unprognostic (5.11e-2)" "unprognostic (2.39e-2)" "unprognostic (4.69e-2)" "unprognostic (2.53e-1)" "unprognostic (1.36e-2)" "unprognostic (2.03e-1)" "unprognostic (1.48e-4)" 0.1 0.9 0.1 0.1 0.0 0.0 0.2 1.2 0.1 0.0 69.2 0.3 5.3 0.0 0.0 8.1 0.0 0.1 0.2 6.1 0.0 0.2 0.2 0.4 0.4 0.7 0.3 0.0 4.3 49.7 0.0 0.1 0.1 1.2 0.0 0.0 4.2 3.3 753.6 0.2 0.9 0.0 0.9 0.0 36.1 1.4 1.4 0.2 0.3 385.3 0.9 0.3 0.0 0.0 0.3 1.3 0.0 1.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 1.2 1.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 2.9 2.0 0.0 0.0 0.0 0.0 1.4 0.3 0.0 2.8 0.6 0.0 0.1 0.2 0.1 0.0 0.0 1.2 1.2 0.0 0.0 0.0 0.6 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.2 0.1 6.1 0.0 0.7 0.3 0.1 0.9 1.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.1 0.0 0.0 0.5 1.3 0.0 0.0 11.2 0.0 0.0 0.0 1.1 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.7 0.1 0.2 8.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FCGR2A "CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, IGFR2" ENSG00000143226 "Fc fragment of IgG receptor IIa" P12318 1 161505430-161524013 "CD markers, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Immunity "IgG-binding protein, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 101.7;placenta: 107.3" "Cell type enhanced" "Detected in many" "Hofbauer cells: 178.2;Kupffer cells: 159.1;Langerhans cells: 336.6;Macrophages: 305.0;monocytes: 97.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 6 "neutrophil: 2322.4" "Lineage enriched" "Detected in many" 6 "granulocytes: 2322.4" "Cell line enhanced" "Detected in some" "HEL: 29.4;HMC-1: 56.2;K-562: 17.9;NB-4: 15.8;THP-1: 61.9;U-937: 26.7" "HPA010718, HPA010776, HPA014730" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA 46000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 19: Lung - Lung function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" "Golgi apparatus" "HPA010718: AB_1078463, HPA010776: , HPA014730: AB_2669074" "unprognostic (2.57e-2)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (4.12e-2)" "unprognostic (5.89e-2)" "unprognostic (6.17e-2)" "unprognostic (1.24e-2)" "unprognostic (1.17e-1)" "unprognostic (7.63e-2)" "unprognostic (1.17e-3)" "unprognostic (2.43e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (6.49e-7)" "unprognostic (8.85e-3)" "unprognostic (6.47e-3)" "unprognostic (1.54e-1)" "unprognostic (3.42e-2)" 68.0 24.8 7.3 101.7 6.6 48.6 13.3 8.0 12.1 18.1 13.9 16.0 8.1 7.3 4.3 11.7 14.6 36.8 11.5 6.5 11.5 12.7 12.3 77.5 16.1 15.1 11.4 7.2 12.7 8.5 7.6 107.3 13.3 6.1 21.0 2.3 9.9 9.6 2.6 3.5 10.8 40.9 11.9 61.8 10.1 4.4 13.8 9.8 6.4 10.2 7.7 68.3 5.2 21.8 0.0 0.0 0.0 2.4 0.0 0.3 0.0 0.0 0.5 0.0 0.1 0.0 0.0 2.3 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 29.4 0.3 0.0 0.7 8.6 56.2 0.5 0.0 0.0 0.0 0.7 0.1 0.0 17.9 0.5 0.0 0.0 0.4 15.8 0.0 0.0 1.1 0.2 1.2 8.1 0.0 0.0 0.1 0.0 0.0 0.0 4.6 0.0 0.0 61.9 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.7 0.4 26.7 6.6 2.4 358.3 421.8 0.7 268.4 1.0 3.2 0.5 0.4 89.9 1.7 0.4 0.7 2322.4 0.4 232.7 3.8 0.9 170.3 7.3 6.6 8.0 12.1 6.5 11.5 15.1 11.4 13.3 11.9 13.8 21.8 2.3 22.4 49.1 0.0 8.6 8.7 0.9 0.3 1.2 0.4 1.1 3.8 1.8 2.8 12.1 0.0 0.0 1.0 3.4 0.1 9.8 0.2 38.2 0.1 0.8 15.6 0.0 3.0 0.1 0.6 1.6 8.9 1.1 0.1 30.4 0.1 3.9 2.1 178.2 0.0 0.1 0.0 0.0 159.1 336.6 66.5 1.5 305.0 17.8 12.2 97.3 0.5 7.2 1.0 0.6 0.5 0.0 0.0 4.6 0.3 0.0 9.6 3.7 0.2 6.6 1.5 6.0 0.4 0.6 0.8 7.7 1.6 4.8 0.2 0.1 0.4 FGD1 "FGDY, ZFYVE3" ENSG00000102302 "FYVE, RhoGEF and PH domain containing 1" P98174 X 54445454-54496234 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 16.1;Granulosa cells: 12.6;Inhibitory neurons: 15.2" "Cancer enhanced" "Detected in all" "testis cancer: 28.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000911, HPA076516" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 35: Non-specific - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA000911: AB_1078853, HPA076516: " "unprognostic (2.49e-1)" "unprognostic (1.56e-1)" "unprognostic (1.64e-2)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.17e-1)" "unprognostic (1.02e-1)" "unprognostic (3.36e-2)" "unprognostic (8.74e-2)" "unprognostic (1.57e-2)" "unprognostic (2.94e-2)" "unprognostic (2.77e-3)" "unprognostic (1.49e-1)" "unprognostic (3.40e-3)" "unprognostic (1.70e-2)" "unprognostic (4.92e-2)" "unprognostic (3.41e-2)" "unprognostic (9.40e-3)" 3.9 5.1 8.2 1.6 6.2 0.0 3.6 5.3 7.6 7.0 2.4 5.6 1.0 7.1 1.6 5.8 5.1 2.2 5.0 8.3 5.2 3.5 1.1 2.8 0.5 3.8 4.1 7.4 3.2 3.6 3.6 3.4 3.7 4.3 1.6 1.6 3.4 3.3 1.3 5.4 2.8 5.4 3.5 2.4 3.5 2.4 4.9 0.4 3.3 1.0 1.0 4.8 5.4 4.6 18.5 6.9 13.2 19.3 7.8 13.8 6.2 10.4 12.8 10.6 8.5 0.6 0.4 0.0 8.2 19.9 9.6 5.3 14.6 9.0 5.8 1.0 8.9 0.0 5.0 2.2 8.3 0.0 0.0 11.3 5.6 16.1 7.6 9.4 9.7 2.3 2.0 0.0 8.4 2.4 0.7 0.0 12.6 0.0 10.2 9.4 6.7 0.0 9.1 0.3 13.1 11.9 10.3 0.2 16.6 21.0 10.3 0.4 6.9 10.5 8.7 23.0 9.4 0.1 0.2 0.1 11.0 0.6 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.2 6.2 5.3 7.6 8.3 5.2 3.8 4.1 3.7 3.5 4.9 4.6 3.2 0.0 0.0 4.6 0.0 2.9 1.2 2.0 5.2 2.5 3.2 3.9 3.4 0.0 0.7 0.0 0.0 0.5 0.1 0.2 0.0 1.6 0.4 1.3 7.0 4.2 1.2 0.0 16.1 1.1 1.0 5.1 1.5 2.1 0.0 12.6 2.9 0.3 0.4 1.7 15.2 1.0 0.0 0.0 1.0 0.6 2.8 0.1 7.2 5.6 0.0 2.3 0.0 7.1 1.8 0.5 0.5 4.1 0.1 1.6 0.1 1.4 0.3 3.5 0.0 2.3 4.0 0.3 2.2 5.5 4.1 0.3 0.1 2.9 2.8 1.0 FGR "c-fgr, p55c-fgr, SRC2" ENSG00000000938 "FGR proto-oncogene, Src family tyrosine kinase" P09769 1 27612064-27635185 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 207.8;lung: 86.5;lymphoid tissue: 141.1" "Cell type enhanced" "Detected in many" "Kupffer cells: 182.2;Langerhans cells: 63.8;Macrophages: 155.9;monocytes: 159.7;NK-cells: 259.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "Daudi: 86.0;U-266/70: 153.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA002024 Enhanced Approved "Plasma membrane,Aggresome" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Aggresome "HPA002024: AB_1078503" "unprognostic (2.66e-2)" "unprognostic (1.51e-2)" "unprognostic (6.32e-2)" "unprognostic (9.74e-3)" "unprognostic (6.66e-3)" "unprognostic (6.71e-2)" "unprognostic (5.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.81e-2)" "unprognostic (7.45e-2)" "unprognostic (2.79e-2)" "unprognostic (1.10e-1)" "unprognostic (1.94e-2)" "unprognostic (6.26e-2)" "unprognostic (3.93e-2)" "unprognostic (2.30e-1)" "unprognostic (8.12e-3)" 25.0 6.8 12.8 62.2 11.9 207.8 16.0 11.9 19.1 7.6 11.5 6.0 3.9 8.1 1.7 5.2 15.6 12.7 8.7 11.4 12.3 7.5 10.8 86.5 27.5 13.6 12.7 2.9 5.8 1.6 2.7 7.9 14.5 7.2 4.0 0.7 6.6 2.4 3.2 4.5 10.1 16.3 12.5 141.1 5.9 2.5 17.2 8.4 7.4 6.5 20.0 17.8 7.3 12.6 0.0 0.0 0.3 0.0 0.5 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 86.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.7 0.0 0.0 0.0 1.7 29.3 0.3 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.3 0.0 0.0 3.8 5.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 153.1 2.1 6.5 0.0 19.5 0.0 30.8 381.4 229.4 189.5 469.1 11.3 54.0 15.8 89.1 196.1 84.0 8.0 78.4 272.9 264.5 405.2 9.0 1.2 494.1 12.8 11.9 11.9 19.1 11.4 12.3 13.6 12.7 14.5 12.5 17.2 12.6 8.6 6.4 20.0 0.0 24.9 2.8 0.6 0.2 0.0 0.0 0.4 0.6 1.6 1.5 5.7 1.8 0.0 0.5 55.2 0.0 0.0 0.0 0.3 0.1 0.2 14.9 0.0 7.4 0.2 0.2 0.7 2.7 1.5 0.1 13.3 0.1 6.8 1.9 56.8 0.0 0.1 0.0 0.0 182.2 63.8 0.7 0.3 155.9 1.8 6.5 159.7 0.1 259.5 1.0 0.4 0.0 1.2 0.0 4.2 0.4 0.0 0.7 1.5 0.0 0.0 0.7 0.6 0.2 0.5 0.5 1.1 1.0 28.0 0.0 0.0 2.5 FHIT "AP3Aase, FRA3B" ENSG00000189283 "Fragile histidine triad diadenosine triphosphatase" P49789 3 59747277-61251459 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" Hydrolase "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "choroid plexus: 94.0" "Cell type enhanced" "Detected in many" "Astrocytes: 609.8;Inhibitory neurons: 450.5;Microglial cells: 337.3;Oligodendrocyte precursor cells: 1086.7;Oligodendrocytes: 1111.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "naive CD4 T-cell: 87.6" "Lineage enriched" "Detected in all" 12 "T-cells: 87.6" "Cell line enhanced" "Detected in many" "RPMI-8226: 17.5;U-266/70: 34.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002684, HPA018840, HPA018909" Enhanced Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 12000 "Cluster 32: T-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 29: U-266 - Adaptive immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoli fibrillar center, Plasma membrane" "CAB002684: , HPA018840: AB_1848538, HPA018909: AB_1848537" "unprognostic (2.36e-3)" "unprognostic (6.38e-2)" "unprognostic (1.59e-1)" "unprognostic (4.42e-2)" "unprognostic (1.10e-1)" "unprognostic (1.08e-2)" "unprognostic (1.18e-1)" "unprognostic (3.16e-2)" "unprognostic (2.77e-2)" "unprognostic (8.49e-2)" "unprognostic (2.36e-1)" "unprognostic (6.77e-2)" "prognostic favorable (1.36e-4)" "unprognostic (1.54e-1)" "unprognostic (5.96e-2)" "unprognostic (1.29e-2)" "unprognostic (1.80e-2)" 5.6 24.4 13.7 6.2 18.3 8.0 9.0 13.0 17.3 5.4 94.0 6.9 6.4 3.5 6.9 5.0 6.6 9.8 15.8 19.7 16.4 24.9 9.6 4.7 7.6 18.9 17.0 6.8 13.0 18.1 7.9 3.0 18.9 5.3 5.8 7.6 8.5 4.7 10.6 8.1 5.3 4.7 15.0 5.0 8.6 5.5 15.9 12.1 11.7 7.2 5.3 6.7 4.2 19.8 0.1 0.0 1.4 0.0 0.6 0.1 2.5 0.1 0.2 0.1 0.0 2.7 4.2 4.0 0.7 0.1 3.0 0.0 12.7 3.2 0.0 2.2 5.0 3.3 2.0 6.4 3.3 8.7 0.1 9.1 5.2 0.2 6.9 0.3 0.0 3.7 2.5 11.9 0.2 3.6 15.2 6.7 1.2 12.2 0.9 11.3 0.0 17.5 15.3 2.0 2.9 4.3 1.5 9.9 10.1 5.3 0.4 0.2 0.0 1.7 0.4 0.1 2.4 34.6 11.3 0.0 4.0 0.1 1.9 6.8 4.6 0.5 2.2 2.9 1.4 4.1 17.2 1.8 5.7 3.1 87.6 15.6 0.8 7.2 1.3 5.8 20.5 11.9 13.7 18.3 13.0 17.3 19.7 16.4 18.9 17.0 18.9 15.0 15.9 19.8 4.1 6.4 10.6 609.8 19.7 7.6 20.7 30.0 46.7 12.6 41.2 31.2 10.0 38.6 17.5 27.6 58.4 42.0 12.4 6.9 78.2 19.1 45.8 14.6 7.9 7.0 7.7 17.7 276.6 4.7 8.5 10.1 18.3 19.0 5.7 25.7 14.6 23.4 20.9 30.3 450.5 12.9 22.4 10.2 7.1 163.0 19.3 12.9 12.4 337.3 8.6 19.7 6.2 1086.7 1111.0 9.7 15.0 9.8 23.8 12.0 20.7 126.6 12.4 20.7 0.0 10.7 6.2 19.1 7.5 33.7 11.2 32.7 11.5 23.0 20.1 18.8 FHL1 "bA535K18.1, FHL1B, FLH1A, KYO-T, MGC111107, SLIM1, XMPMA" ENSG00000022267 "Four and a half LIM domains 1" Q13642 X 136146702-136211359 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Emery-Dreifuss muscular dystrophy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 7 "skeletal muscle: 11467.1;tongue: 9770.8" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 1145.1;Early spermatids: 373.8;Late spermatids: 1206.9" "Cancer enhanced" "Detected in all" "renal cancer: 88.1" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "NK-cell: 36.1" "Group enriched" "Detected in many" 4 "dendritic cells: 19.4;NK-cells: 36.1;T-cells: 18.2" "Cell line enhanced" "Detected in many" "BJ hTERT+: 303.7;fHDF/TERT166: 258.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001040, HPA001391, CAB020817" Enhanced Supported "Plasma membrane,Cytosol" NA NA 12000000 "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "CAB020817: , HPA001040: AB_1848541, HPA001391: AB_1848542" "unprognostic (2.16e-1)" "unprognostic (5.13e-2)" "unprognostic (1.33e-2)" "unprognostic (1.89e-1)" "unprognostic (1.61e-3)" "unprognostic (1.76e-2)" "unprognostic (2.51e-2)" "unprognostic (9.34e-2)" "unprognostic (7.12e-3)" "unprognostic (1.20e-1)" "unprognostic (2.21e-3)" "unprognostic (1.72e-1)" "unprognostic (6.17e-3)" "unprognostic (4.04e-2)" "unprognostic (7.52e-2)" "unprognostic (2.05e-3)" "prognostic unfavorable (2.11e-4)" 938.4 65.8 120.8 75.5 117.2 11.7 441.8 95.9 126.3 315.5 85.8 672.0 83.2 464.6 107.7 538.1 281.6 127.6 1462.3 130.8 144.9 45.2 43.1 285.6 41.7 103.9 125.4 102.8 39.4 196.5 92.9 106.6 115.9 408.8 161.4 76.2 161.3 541.1 11467.1 101.3 235.5 486.5 114.8 43.0 368.4 60.2 130.1 25.1 310.1 9770.8 32.1 469.6 253.1 102.9 0.4 44.3 60.7 57.8 127.2 52.3 1.5 183.7 303.7 34.8 81.3 0.3 12.7 0.7 55.8 258.8 95.0 0.5 119.2 148.0 28.2 0.4 136.7 0.7 34.4 0.0 121.6 0.3 26.8 96.6 24.4 41.2 128.7 14.1 36.6 34.5 0.1 26.0 81.9 2.5 26.1 1.6 19.1 0.2 52.2 69.8 2.6 38.2 1.1 0.1 43.5 63.8 6.6 0.2 12.4 24.1 0.3 2.4 102.5 150.2 71.0 5.9 44.7 6.8 16.0 1.1 11.9 1.4 18.2 0.1 0.7 0.0 5.2 0.1 13.8 5.8 18.2 7.2 3.1 3.6 12.0 4.0 1.2 36.1 0.0 19.4 2.2 11.1 120.8 117.2 95.9 126.3 130.8 144.9 103.9 125.4 115.9 114.8 130.1 102.9 203.0 48.1 11.7 32.0 8.1 56.5 26.9 15.1 14.2 36.2 1.4 8.3 1145.1 0.0 4.9 11.0 8.4 0.6 8.6 0.5 1.9 3.0 373.8 4.3 32.3 61.1 13.8 17.9 70.2 0.2 1.1 236.0 2.0 2.0 15.8 41.0 113.6 6.1 4.3 99.3 55.6 0.8 0.0 5.1 47.0 1206.9 123.9 35.6 32.0 16.9 7.4 209.6 2.1 35.2 8.2 0.6 7.6 152.4 15.5 20.1 0.6 11.6 4.8 19.4 105.2 248.1 235.7 7.4 88.6 2.7 44.8 2.7 15.5 9.6 2.0 2.6 FILIP1 "FILIP, KIAA1275" ENSG00000118407 "Filamin A interacting protein 1" Q7Z7B0 6 75291859-75493800 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 53.8;skeletal muscle: 35.8;tongue: 48.9" "Cell type enriched" "Detected in many" 4 "Cardiomyocytes: 582.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 6.9;HUVEC TERT2: 1.7;RPTEC TERT1: 1.9;U-266/70: 6.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA053564 Enhanced Approved "Plasma membrane,Actin filaments" No NA "Cluster 38: Heart - Muscle contraction" "Cluster 29: U-266 - Adaptive immune response" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA053564: AB_2682192" "unprognostic (4.90e-2)" "unprognostic (3.77e-2)" "unprognostic (9.77e-3)" "unprognostic (3.83e-1)" "unprognostic (1.52e-1)" "unprognostic (4.98e-1)" "unprognostic (2.27e-2)" "unprognostic (1.51e-1)" "unprognostic (1.06e-1)" "unprognostic (5.17e-3)" "unprognostic (3.29e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-3)" "unprognostic (3.97e-3)" "unprognostic (2.34e-1)" "unprognostic (4.65e-2)" "unprognostic (7.66e-3)" 6.8 1.5 1.5 2.9 1.8 0.2 2.4 0.1 2.5 1.8 0.7 11.7 1.8 8.5 0.9 9.5 4.8 5.7 53.8 4.1 0.5 1.8 3.2 7.6 1.2 0.2 0.5 1.3 1.4 12.4 1.4 5.1 0.3 3.9 3.3 0.4 1.2 3.4 35.8 0.6 2.6 13.2 0.5 0.3 3.2 2.1 0.8 1.1 2.3 48.9 0.9 10.9 1.6 1.5 0.0 1.3 0.2 0.1 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.1 6.9 0.0 0.1 0.0 0.1 0.0 0.0 0.2 0.2 0.1 0.2 0.0 0.0 0.1 0.1 0.9 0.0 0.1 0.0 0.0 1.7 0.2 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.9 0.4 0.1 0.1 0.0 0.1 0.0 1.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.9 0.7 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.1 0.0 0.0 1.5 1.8 0.1 2.5 4.1 0.5 0.2 0.5 0.3 0.5 0.8 1.5 82.1 128.2 82.6 5.9 0.5 0.6 0.5 2.8 0.0 3.5 0.5 0.8 582.5 0.0 9.1 0.0 0.0 0.8 0.5 0.1 1.9 0.1 54.2 18.2 1.7 45.9 0.0 2.7 9.7 0.4 0.3 60.3 0.0 19.2 1.3 1.7 72.1 0.7 1.3 0.0 12.8 0.1 8.2 1.9 1.2 17.6 2.5 1.8 1.8 5.6 0.0 2.5 1.0 6.0 10.0 0.0 0.0 4.5 0.0 0.8 0.4 0.1 62.4 3.5 92.1 70.2 114.2 7.1 7.9 0.7 0.9 0.8 1.8 11.9 0.1 0.4 FLACC1 ALS2CR12 ENSG00000155749 "Flagellum associated containing coiled-coil domains 1" Q96Q35 2 201288271-201357398 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 9.8;testis: 17.1" "Cell type enriched" "Detected in single" 8 "Cardiomyocytes: 6.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 3.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "SK-MEL-30: 3.4;U-2197: 5.9" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA035793 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 18: U-2197 - ECM organization" "Cluster 43: Cardiomyocytes - Nuclear processes" "Plasma membrane, Cytosol" "HPA035793: AB_10602429" "unprognostic (1.45e-1)" "unprognostic (1.91e-1)" "unprognostic (9.72e-2)" "unprognostic (2.95e-2)" "unprognostic (1.53e-1)" "unprognostic (8.33e-2)" "unprognostic (1.32e-1)" "unprognostic (8.40e-3)" "unprognostic (1.40e-5)" "unprognostic (1.37e-1)" "unprognostic (3.62e-2)" "unprognostic (1.14e-1)" "unprognostic (6.23e-2)" "unprognostic (1.13e-1)" "unprognostic (2.73e-2)" "unprognostic (2.23e-1)" "unprognostic (8.25e-2)" 0.9 1.1 3.9 1.0 4.3 5.0 0.5 2.8 3.9 0.7 9.8 0.8 0.5 0.7 1.1 1.2 8.3 1.1 4.5 5.0 3.2 1.3 0.7 2.5 1.6 5.8 6.4 0.3 0.9 0.7 1.1 0.8 3.7 0.5 1.0 3.3 1.1 0.8 1.8 1.2 1.0 0.6 4.2 0.8 0.5 17.1 3.0 0.7 1.6 0.4 0.5 0.6 0.4 3.7 0.1 0.2 1.1 0.7 2.7 1.1 0.0 0.8 0.3 0.7 0.4 0.0 0.3 0.2 0.6 1.2 0.4 1.1 0.4 0.1 0.3 0.7 0.1 0.1 1.7 0.4 0.6 1.2 1.0 0.5 0.3 0.7 0.1 0.8 0.1 1.2 0.5 1.6 0.6 0.0 0.6 1.0 0.3 0.4 0.6 0.3 0.5 0.7 0.4 0.2 0.2 0.7 0.7 0.0 3.4 1.0 0.4 1.4 0.9 1.5 0.7 5.9 0.5 0.8 1.8 0.5 1.2 0.6 0.7 3.1 0.4 0.4 0.7 0.3 0.3 0.3 0.4 0.4 0.2 0.7 0.6 0.7 3.6 1.3 0.3 0.2 0.3 0.2 3.9 4.3 2.8 3.9 5.0 3.2 5.8 6.4 3.7 4.2 3.0 3.7 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 FLAD1 "FAD1, PP591" ENSG00000160688 "Flavin adenine dinucleotide synthetase 1" Q8NFF5 1 154983338-154993111 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Nucleotidyltransferase, Transferase" "Disease variant, Primary mitochondrial disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028476, HPA028486, HPA028563" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA028476: AB_10599974, HPA028486: AB_10600206, HPA028563: AB_10602286" "unprognostic (2.64e-1)" "unprognostic (2.60e-1)" "unprognostic (2.72e-1)" "unprognostic (3.84e-2)" "unprognostic (7.34e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (3.04e-4)" "unprognostic (1.31e-1)" "unprognostic (2.32e-1)" "unprognostic (8.08e-2)" "unprognostic (6.51e-2)" "unprognostic (9.74e-2)" "prognostic unfavorable (2.55e-6)" "unprognostic (1.67e-2)" "unprognostic (5.06e-2)" "unprognostic (5.50e-2)" "unprognostic (1.17e-2)" 21.9 21.1 19.2 17.0 20.5 14.2 23.5 20.2 20.7 20.4 19.7 22.8 20.1 19.8 20.5 26.1 19.1 11.8 28.7 20.1 19.5 21.7 32.8 17.7 22.8 20.2 20.3 15.5 18.9 18.0 15.1 14.3 20.6 24.3 18.9 9.8 21.0 13.7 34.1 32.9 24.9 17.7 19.6 30.1 22.0 19.0 20.6 16.0 22.5 32.0 23.0 22.6 21.1 21.0 33.4 52.4 32.8 56.1 27.9 20.5 62.1 24.7 20.5 35.2 30.2 46.9 40.1 38.5 48.8 23.0 18.3 42.6 63.4 51.3 23.0 40.6 47.5 31.4 42.8 33.7 38.1 46.0 39.1 29.5 65.9 40.2 42.8 17.0 41.5 40.4 51.4 30.3 30.2 71.8 31.9 32.0 71.7 72.2 53.8 52.8 16.2 88.7 33.9 45.8 54.9 75.6 38.7 86.2 50.0 63.0 74.0 68.6 26.4 21.9 30.1 28.6 39.6 47.5 63.7 66.9 26.4 36.8 36.1 29.8 35.3 23.7 34.5 33.0 38.9 39.0 31.9 33.8 37.7 34.2 29.1 28.9 7.8 26.1 41.4 38.3 37.9 37.6 19.2 20.5 20.2 20.7 20.1 19.5 20.2 20.3 20.6 19.6 20.6 21.0 12.2 9.6 10.6 9.8 19.3 26.5 18.1 37.1 23.3 15.7 16.4 15.9 39.4 20.0 22.6 25.8 6.2 42.5 16.9 22.1 31.3 24.4 25.3 15.4 12.0 14.1 12.0 19.0 8.2 28.2 42.6 12.1 25.0 12.6 8.8 21.2 11.7 27.0 27.6 15.2 6.3 20.8 28.5 18.1 11.1 77.6 10.2 14.8 14.2 5.6 34.7 23.3 32.0 4.5 8.2 25.4 14.9 9.8 18.3 26.1 30.3 32.9 19.3 17.2 6.6 9.7 18.3 22.9 20.6 25.7 27.6 36.0 20.2 23.1 25.4 20.0 FLCN "BHD, DENND8B, MGC17998, MGC23445" ENSG00000154803 Folliculin Q8NFG4 17 17212212-17237188 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cancer-related genes, Disease variant, Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Cone photoreceptor cells: 79.2;Erythroid cells: 81.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015158, HPA028760" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 72: Non-specific - Transcription" "Cluster 18: U-2197 - ECM organization" "Cluster 6: Erythroid cells - Oxygen transport" Cytosol "Plasma membrane" "CAB015158: AB_2231645, HPA028760: AB_10601323" "unprognostic (1.99e-1)" "unprognostic (1.77e-1)" "unprognostic (1.53e-2)" "unprognostic (1.74e-1)" "unprognostic (3.85e-2)" "unprognostic (3.69e-1)" "unprognostic (3.73e-2)" "unprognostic (1.32e-1)" "unprognostic (3.58e-2)" "unprognostic (3.90e-1)" "prognostic favorable (4.49e-4)" "unprognostic (6.45e-3)" "unprognostic (2.55e-3)" "unprognostic (1.92e-1)" "unprognostic (9.71e-2)" "unprognostic (2.62e-2)" "unprognostic (1.65e-1)" 21.8 19.0 19.0 10.7 25.9 17.7 18.9 27.3 31.6 42.5 18.3 43.7 23.3 37.0 14.5 13.8 25.2 17.0 29.2 31.9 14.0 15.3 28.9 26.8 12.4 21.3 15.2 35.3 15.2 13.1 28.6 13.1 22.0 27.1 10.2 7.2 16.4 13.7 42.7 19.3 26.8 14.5 14.0 29.2 22.4 21.0 19.3 8.6 23.8 18.4 8.0 28.2 25.5 28.3 12.0 30.4 11.5 14.9 36.4 20.6 15.8 11.8 19.1 18.0 24.3 24.3 10.4 6.3 13.8 14.0 40.2 14.4 14.0 7.3 9.3 10.9 12.2 12.4 9.1 13.9 33.6 4.9 33.5 30.3 24.0 27.6 20.8 16.4 14.8 9.2 17.7 16.4 17.6 17.5 8.3 8.4 11.2 17.8 8.1 16.9 52.7 7.3 11.0 14.1 13.6 8.8 11.6 7.5 19.3 70.7 11.1 8.8 15.7 40.6 16.6 56.5 14.1 7.7 7.4 5.7 26.0 10.8 16.6 2.4 2.8 1.6 1.6 3.7 2.2 3.6 1.9 1.4 1.4 3.2 2.1 1.9 6.0 2.8 1.4 1.4 2.9 1.8 19.0 25.9 27.3 31.6 31.9 14.0 21.3 15.2 22.0 14.0 19.3 28.3 8.4 25.6 12.6 17.0 9.2 18.4 12.7 5.7 2.8 20.7 13.2 6.5 23.7 14.3 6.2 7.3 79.2 10.9 5.3 25.0 1.9 12.3 14.5 16.8 11.3 12.5 25.7 81.7 31.3 8.3 7.4 20.6 9.7 15.2 1.3 10.3 27.8 24.1 16.6 47.1 23.7 11.0 16.2 21.6 19.2 20.4 28.0 13.2 10.6 18.7 12.2 13.3 6.2 17.1 32.4 9.8 15.6 20.3 4.4 11.6 36.8 6.1 9.1 18.5 19.7 24.8 11.1 6.3 10.8 5.3 18.2 33.8 10.0 16.3 12.6 13.0 FLNC "ABP-280, ABPL, FLN2" ENSG00000128591 "Filamin C" Q14315 7 128830406-128859274 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Transporters" Actin-binding "Cardiomyopathy, Disease variant, Myofibrillar myopathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 635.2;skeletal muscle: 1384.8;tongue: 442.6" "Cell type enriched" "Detected in many" 26 "Cardiomyocytes: 1892.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 393.6;fHDF/TERT166: 180.2;hTEC/SVTERT24-B: 190.6;U-2 OS: 163.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" "HPA006135, HPA071007" Enhanced Supported "Plasma membrane,Cytosol" NA NA 26000000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA006135: AB_1848602, HPA071007: " "unprognostic (1.25e-1)" "unprognostic (7.38e-2)" "unprognostic (4.47e-2)" "unprognostic (1.40e-2)" "prognostic unfavorable (2.80e-4)" "unprognostic (1.64e-3)" "unprognostic (4.42e-3)" "prognostic unfavorable (2.17e-5)" "unprognostic (1.03e-3)" "unprognostic (2.35e-2)" "unprognostic (1.35e-3)" "unprognostic (6.37e-2)" "prognostic unfavorable (5.69e-4)" "unprognostic (5.68e-3)" "unprognostic (1.15e-1)" "unprognostic (1.52e-3)" "prognostic unfavorable (3.73e-5)" 13.1 3.4 5.8 25.9 11.5 0.0 5.9 11.5 9.9 16.9 3.0 215.4 9.4 96.6 4.6 40.3 35.4 13.8 635.2 5.9 16.7 2.8 1.1 12.5 0.6 52.1 11.1 9.4 2.1 3.2 1.6 2.4 29.9 71.1 9.8 0.5 16.5 100.7 1384.8 8.9 40.3 114.4 51.7 0.7 65.6 2.2 19.1 0.3 4.3 442.6 0.2 162.7 21.3 49.8 0.1 0.8 4.2 0.1 34.4 41.2 4.1 393.6 73.6 109.2 52.3 124.0 1.0 0.1 64.7 180.2 44.9 0.1 23.7 0.9 64.4 0.2 13.1 0.1 20.2 0.1 43.2 0.0 0.2 78.0 0.1 190.6 0.1 44.2 69.0 0.3 49.0 0.2 75.8 0.0 0.0 1.5 64.5 0.1 22.6 0.1 127.5 1.0 0.1 0.0 2.1 7.0 0.7 0.1 0.3 88.0 0.4 1.6 144.6 38.2 163.5 10.1 0.2 0.1 0.0 0.3 129.0 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 11.5 11.5 9.9 5.9 16.7 52.1 11.1 29.9 51.7 19.1 49.8 3.6 3.2 0.5 0.7 0.0 3.7 0.3 0.1 1.2 0.6 0.3 1.3 1892.3 0.0 1.9 1.8 0.0 0.4 0.2 0.5 0.0 0.7 0.4 1.8 5.0 31.4 0.0 0.0 0.2 0.2 3.0 31.6 0.0 2.9 0.0 0.6 1.8 0.0 0.9 0.0 1.1 0.3 0.0 0.0 6.9 0.9 5.3 0.5 5.4 0.0 0.0 0.1 0.0 0.0 5.8 2.6 0.1 10.5 1.2 2.7 0.0 1.1 0.0 0.2 0.0 71.8 38.1 0.3 1.0 0.2 4.5 1.9 1.0 0.1 0.2 1.0 FLOT2 "ECS-1, ECS1, ESA, ESA1, M17S1" ENSG00000132589 "Flotillin 2" Q14254 17 28879335-28897733 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001396, CAB004395, HPA071038" Supported Supported "Vesicles,Plasma membrane" NA NA 170000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 44: HDLM-2 - Immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" Vesicles "CAB004395: AB_627618, HPA001396: AB_1078894, HPA071038: " "unprognostic (6.04e-2)" "unprognostic (8.76e-3)" "unprognostic (3.01e-1)" "unprognostic (8.92e-2)" "unprognostic (4.15e-3)" "unprognostic (2.17e-2)" "unprognostic (4.36e-3)" "unprognostic (2.12e-1)" "unprognostic (5.21e-2)" "unprognostic (1.20e-1)" "unprognostic (9.98e-2)" "unprognostic (2.80e-1)" "unprognostic (4.12e-3)" "unprognostic (2.64e-2)" "unprognostic (1.09e-1)" "unprognostic (1.11e-3)" "unprognostic (2.20e-2)" 60.2 46.4 38.4 56.8 38.6 97.1 56.2 28.1 47.6 42.8 45.2 58.9 21.0 39.1 21.2 69.3 46.8 27.0 63.5 41.1 42.5 71.4 98.4 59.5 68.2 45.9 37.1 37.7 38.8 30.0 22.3 58.4 41.3 67.8 27.2 20.3 61.7 51.6 51.6 38.2 53.0 35.3 37.5 122.7 44.6 10.4 47.1 47.8 39.6 44.1 63.6 78.8 49.6 36.1 55.5 90.8 69.6 60.2 33.6 44.2 76.6 42.5 57.9 60.9 71.3 96.0 45.7 76.9 79.3 47.6 42.0 63.3 76.5 69.7 25.9 245.5 91.4 92.7 80.5 70.3 43.6 76.8 15.2 53.3 53.6 49.3 66.9 64.1 97.4 21.8 89.0 65.6 28.9 83.5 21.2 54.0 61.4 48.6 24.6 32.6 70.6 189.3 92.0 166.9 61.9 103.3 99.8 69.6 77.5 66.7 72.3 136.3 81.5 21.4 38.2 35.2 65.0 36.5 68.2 39.5 59.9 72.3 40.7 171.9 106.0 213.2 98.8 96.6 72.6 98.5 74.6 84.5 144.3 118.1 55.3 69.0 415.2 78.5 110.2 38.8 97.6 143.2 38.4 38.6 28.1 47.6 41.1 42.5 45.9 37.1 41.3 37.5 47.1 36.1 34.2 22.4 21.9 12.7 46.8 12.6 27.1 20.6 29.6 6.9 24.9 30.1 32.9 22.8 16.5 20.2 10.4 96.6 20.5 29.0 15.6 39.3 13.0 25.8 13.2 37.0 25.8 49.2 17.0 31.1 68.9 14.8 23.0 27.6 6.3 15.6 48.9 45.1 44.4 5.0 19.2 25.9 10.2 43.3 22.6 42.3 10.8 31.1 8.8 22.5 75.2 10.7 35.0 16.1 11.0 32.2 16.5 8.6 27.8 14.8 14.8 26.7 19.1 12.4 19.7 7.1 13.4 1.6 6.9 42.4 9.2 37.1 32.5 4.2 32.0 26.7 FLT1 "FLT, VEGFR1" ENSG00000102755 "Fms related receptor tyrosine kinase 1" P17948 13 28300346-28495145 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Angiogenesis, Chemotaxis, Differentiation" "Developmental protein, Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "placenta: 432.4" "Cell type enhanced" "Detected in many" "Adipocytes: 411.6;Endothelial cells: 263.1;Extravillous trophoblasts: 815.4;Hepatic stellate cells: 234.9;Microglial cells: 433.8;Syncytiotrophoblasts: 1127.1" "Cancer enhanced" "Detected in all" "renal cancer: 28.7" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 71.8;BJ hTERT+: 57.2;HMC-1: 349.2;HUVEC TERT2: 64.9;WM-115: 127.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011740, HPA014290, CAB068189, CAB068190" Enhanced Supported "Plasma membrane,Actin filaments" "Secreted to blood" NA NA 876000 87000 "Cluster 21: B-cells - Adaptive immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Actin filaments" "CAB068189: AB_2665636, CAB068190: AB_2665637, HPA011740: AB_1858737, HPA014290: AB_1858738" "unprognostic (3.33e-2)" "unprognostic (3.52e-3)" "unprognostic (1.13e-3)" "unprognostic (5.02e-2)" "unprognostic (3.65e-1)" "unprognostic (5.03e-2)" "unprognostic (8.25e-2)" "unprognostic (2.27e-3)" "unprognostic (9.91e-2)" "unprognostic (6.61e-2)" "unprognostic (2.33e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.19e-4)" "unprognostic (4.20e-2)" "unprognostic (6.00e-2)" "unprognostic (1.57e-1)" "unprognostic (6.32e-2)" 47.6 9.6 37.6 9.1 36.2 1.1 31.2 37.0 43.0 16.4 24.6 9.4 7.5 17.2 3.7 5.9 11.7 16.6 46.0 33.3 39.8 34.9 18.2 25.8 5.3 44.6 40.0 4.4 12.7 30.5 9.0 432.4 50.1 13.9 6.1 52.5 7.0 11.0 19.9 5.9 9.3 17.4 33.4 18.6 10.9 17.4 59.6 3.6 48.9 38.8 5.7 14.0 9.5 38.7 0.1 0.0 0.0 0.6 0.6 0.9 0.3 71.8 57.2 25.8 14.9 0.0 0.2 0.1 0.1 9.6 0.0 0.3 6.7 0.0 45.4 0.0 2.0 0.2 0.1 0.0 0.1 0.0 349.2 0.6 0.0 0.1 1.0 0.1 64.9 6.1 1.7 0.3 0.0 0.3 4.5 3.7 37.5 0.0 0.1 2.9 0.0 0.1 0.1 0.1 8.1 0.6 0.0 0.1 0.2 44.4 0.3 0.2 6.3 0.2 1.2 0.1 0.1 2.1 1.0 0.2 0.4 0.3 127.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.8 0.1 0.1 0.5 0.0 0.0 0.1 0.0 0.0 37.6 36.2 37.0 43.0 33.3 39.8 44.6 40.0 50.1 33.4 59.6 38.7 411.6 0.0 6.0 2.0 4.7 4.1 0.7 0.2 3.4 17.8 1.2 1.5 26.5 2.8 2.9 0.0 4.2 197.2 1.4 0.1 1.9 0.6 157.2 0.5 1.5 263.1 0.0 0.0 0.9 0.0 815.4 32.1 0.5 2.1 1.3 0.1 234.9 6.9 30.8 1.7 14.5 0.0 0.0 12.5 23.6 173.8 18.6 15.3 0.0 433.8 0.0 153.2 0.0 9.5 2.0 0.0 0.0 48.5 4.1 1.3 0.0 0.1 1.8 9.7 92.1 11.4 30.1 14.6 4.6 1.0 4.8 1127.1 2.8 1.5 0.0 1.1 FMN2 ENSG00000155816 "Formin 2" Q9NZ56 1 240014348-240475187 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, Protein transport, Stress response, Transport" "Actin-binding, Developmental protein" "Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 46.0;parathyroid gland: 19.7;retina: 16.7" "Cell type enhanced" "Detected in many" "Astrocytes: 758.1;Excitatory neurons: 537.5;Horizontal cells: 124.5;Inhibitory neurons: 366.7;Oligodendrocyte precursor cells: 154.3" "Group enriched" "Detected in some" 8 "glioma: 5.9;testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ: 70.8;BJ hTERT+: 39.4;fHDF/TERT166: 73.8;LHCN-M2: 87.9;U-138 MG: 48.9;WM-115: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050649 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Actin filaments" "HPA050649: AB_2681202" "unprognostic (1.55e-2)" "unprognostic (8.21e-2)" "unprognostic (4.01e-2)" "unprognostic (8.06e-2)" "unprognostic (2.77e-1)" "unprognostic (1.76e-1)" "unprognostic (7.97e-3)" "unprognostic (2.11e-2)" "unprognostic (2.93e-1)" "unprognostic (3.92e-2)" "unprognostic (3.35e-3)" "unprognostic (4.08e-1)" "unprognostic (1.11e-2)" "unprognostic (8.03e-3)" "unprognostic (9.78e-2)" "unprognostic (3.10e-2)" "unprognostic (1.40e-3)" 1.2 5.1 27.6 0.2 29.6 0.0 0.5 11.8 46.0 0.4 0.0 6.8 0.2 1.4 0.9 0.7 1.9 1.2 0.1 28.4 20.9 3.6 0.0 0.3 0.0 21.2 29.7 2.4 1.0 19.7 9.0 0.2 14.4 1.6 1.6 16.7 0.3 2.6 0.1 0.2 0.9 1.7 16.0 0.2 0.7 2.2 39.0 0.0 0.5 0.2 0.1 0.3 0.3 30.9 0.0 2.1 6.6 0.0 20.2 15.3 0.0 70.8 39.4 31.0 16.3 0.0 0.0 0.0 0.0 73.8 1.2 0.0 1.3 0.0 28.8 0.0 5.8 0.0 0.7 0.0 0.1 0.0 0.0 1.7 0.0 8.5 1.9 17.0 0.0 0.0 0.0 0.0 87.9 0.0 0.0 0.1 2.3 0.0 2.2 0.0 0.2 0.0 0.0 0.0 12.0 10.6 0.0 0.1 0.3 0.2 2.1 0.1 0.3 48.9 0.2 16.0 18.2 0.0 0.0 0.0 10.4 0.0 69.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.6 29.6 11.8 46.0 28.4 20.9 21.2 29.7 14.4 16.0 39.0 30.9 0.0 0.0 0.0 758.1 0.0 0.1 0.0 0.0 0.0 30.6 0.2 0.3 1.6 0.0 0.0 1.8 50.1 0.1 0.0 4.7 0.0 0.0 15.2 4.3 0.7 0.5 12.1 0.0 537.5 0.0 0.1 1.4 0.0 1.1 0.0 0.8 2.9 0.1 0.1 124.5 366.7 0.5 0.0 0.6 0.6 3.0 0.3 0.1 1.8 31.9 0.0 2.3 0.0 154.3 17.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.0 0.0 0.3 1.8 4.4 0.0 0.0 0.5 0.0 3.1 1.6 0.0 FNBP1 "FBP17, KIAA0554" ENSG00000187239 "Formin binding protein 1" Q96RU3 9 129887187-130043194 "Disease related genes, Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 317.7;Langerhans cells: 402.9;monocytes: 433.2;Oligodendrocytes: 522.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HDLM-2: 137.7;JURKAT: 143.2;MOLT-4: 140.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019635, HPA019691, HPA022119, HPA067742" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 37: B-cells - Transcription" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Vesicles "HPA019635: AB_2732423, HPA019691: AB_2670231, HPA022119: AB_2670897, HPA067742: " "unprognostic (2.86e-1)" "unprognostic (2.59e-3)" "unprognostic (1.22e-2)" "unprognostic (2.10e-1)" "unprognostic (3.20e-1)" "unprognostic (1.43e-2)" "unprognostic (6.30e-3)" "unprognostic (9.10e-2)" "unprognostic (2.90e-1)" "unprognostic (6.17e-2)" "unprognostic (9.26e-2)" "unprognostic (2.65e-1)" "prognostic unfavorable (8.45e-5)" "unprognostic (6.84e-2)" "unprognostic (1.37e-1)" "unprognostic (2.10e-1)" "unprognostic (1.21e-1)" 21.8 11.9 51.2 57.8 73.7 40.6 16.4 77.4 53.4 32.5 22.2 107.3 15.0 50.0 17.0 39.4 34.8 27.8 15.1 47.0 62.5 16.4 18.4 25.4 78.1 67.6 69.1 22.1 8.1 10.7 17.7 16.3 65.8 41.4 29.6 12.6 16.3 44.1 24.1 25.9 37.6 46.8 55.9 60.9 29.6 17.3 69.9 111.0 33.4 13.2 74.3 68.4 26.8 86.6 42.5 19.3 34.9 40.8 21.0 25.8 29.5 23.7 20.2 17.6 14.7 20.3 16.2 82.9 20.4 44.5 20.8 20.7 33.0 21.6 17.6 137.7 9.8 22.8 22.8 13.8 35.8 62.3 75.1 18.7 9.3 32.6 19.5 25.6 26.1 143.2 5.4 1.1 16.4 34.0 140.1 60.8 27.5 5.7 32.6 31.9 28.3 24.1 22.1 23.0 5.5 17.6 43.3 42.9 16.5 33.3 30.0 28.3 31.9 16.6 20.7 30.5 15.0 16.4 64.4 3.8 20.0 42.2 25.2 13.2 5.1 9.6 10.8 5.6 9.3 12.7 9.7 10.3 5.8 7.7 8.9 8.6 9.3 6.0 6.5 6.9 10.9 4.5 51.2 73.7 77.4 53.4 47.0 62.5 67.6 69.1 65.8 55.9 69.9 86.6 27.2 35.3 25.2 317.7 180.4 33.1 21.3 12.8 21.6 20.2 42.5 24.6 14.8 15.7 29.8 22.0 52.1 18.6 217.2 28.3 19.6 22.6 1.7 46.2 38.8 38.3 18.1 31.3 65.6 17.3 24.5 38.8 26.5 78.7 80.4 9.2 71.0 18.4 43.6 28.6 107.8 8.7 20.3 221.2 402.9 5.5 46.6 131.1 76.5 95.5 433.2 42.8 223.5 69.4 522.1 21.8 19.8 51.6 147.9 67.8 0.2 15.0 42.3 29.5 59.2 19.9 41.0 26.5 45.4 26.7 41.1 63.9 233.7 7.1 16.2 42.3 FOXN3 "C14orf116, CHES1" ENSG00000053254 "Forkhead box N3" O00409 14 89124871-89619149 "Predicted intracellular proteins, Transcription factors" "Cell cycle, Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Microglial cells: 517.2;Oligodendrocyte precursor cells: 291.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HDLM-2: 109.2;U-266/84: 112.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA059209 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 44: HDLM-2 - Immune response" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane" "HPA059209: AB_2683949" "unprognostic (1.69e-1)" "unprognostic (6.13e-3)" "unprognostic (2.08e-1)" "unprognostic (1.84e-1)" "unprognostic (4.09e-2)" "unprognostic (2.03e-1)" "unprognostic (3.03e-1)" "unprognostic (1.34e-2)" "unprognostic (8.75e-2)" "unprognostic (1.09e-1)" "unprognostic (2.64e-1)" "unprognostic (1.19e-1)" "prognostic favorable (9.58e-5)" "unprognostic (2.22e-2)" "unprognostic (1.88e-1)" "unprognostic (5.53e-2)" "unprognostic (2.11e-1)" 46.5 27.0 17.8 23.6 17.9 83.7 22.8 76.2 15.1 24.9 33.4 28.8 36.7 26.5 9.2 39.4 23.2 22.9 38.2 12.2 15.8 12.8 30.8 23.9 29.1 20.5 18.3 50.6 24.8 46.9 5.1 22.7 21.5 20.2 21.8 16.5 18.4 22.1 79.6 41.4 35.2 35.1 19.3 21.6 29.0 16.8 21.5 41.6 9.5 72.6 30.9 25.5 20.6 18.3 0.5 7.7 19.7 11.3 78.1 24.8 14.2 15.7 15.4 13.8 22.7 7.8 6.3 24.0 7.8 25.0 9.5 5.6 33.5 22.3 20.4 109.2 6.2 8.3 14.6 25.0 25.3 16.6 14.1 59.4 12.6 1.3 9.4 16.6 30.2 34.1 10.0 69.0 22.9 9.4 32.2 16.6 21.2 14.2 13.8 51.4 67.0 22.8 1.7 26.6 10.7 35.1 23.0 21.9 6.4 64.8 12.8 45.3 55.0 23.5 32.1 23.6 23.6 58.4 112.6 44.6 8.5 28.2 13.8 48.8 23.8 35.8 41.9 25.7 33.3 13.5 27.8 35.9 35.2 16.4 35.8 34.6 9.6 32.2 17.3 7.9 35.9 31.2 17.8 17.9 76.2 15.1 12.2 15.8 20.5 18.3 21.5 19.3 21.5 18.3 108.7 32.1 33.9 229.5 65.4 89.3 22.4 27.4 41.5 123.2 21.0 21.7 103.2 47.1 53.4 9.2 0.0 36.9 105.9 37.2 21.5 11.5 86.2 38.8 36.3 67.3 59.3 52.5 125.6 20.9 21.3 75.2 45.9 36.4 12.7 112.4 55.6 92.9 43.5 79.1 195.2 37.5 30.5 100.3 174.9 38.5 96.3 87.9 32.0 517.2 65.3 38.6 94.7 291.6 143.8 15.5 32.1 85.4 71.3 16.8 77.4 12.2 16.0 9.9 39.5 133.6 57.9 4.3 11.6 51.4 147.6 29.6 85.0 37.2 46.6 29.1 FP565260.3 ENSG00000277117 "ICOS ligand" 21 5022493-5040666 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "brain: 17.4" "Cell type enriched" "Detected in single" 6 "monocytes: 4.6" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BEWO: 22.8;REH: 18.5;SiHa: 15.6" HPA029179 Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 70: Brain - Nervous system development" "Cluster 28: BEWO - Transcription regulation" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane, Cytoplasmic bodies" "HPA029179: AB_2732445" "unprognostic (3.34e-2)" "unprognostic (1.52e-1)" "unprognostic (2.82e-1)" "unprognostic (3.58e-4)" "unprognostic (6.66e-4)" "unprognostic (1.24e-2)" "unprognostic (1.12e-1)" "unprognostic (3.36e-1)" "unprognostic (2.46e-1)" "unprognostic (6.63e-2)" "unprognostic (1.14e-1)" "unprognostic (7.43e-2)" "unprognostic (2.13e-1)" "unprognostic (3.17e-1)" "unprognostic (3.60e-2)" "unprognostic (1.12e-1)" "unprognostic (2.09e-1)" 2.8 1.5 6.1 4.7 12.8 3.7 2.4 8.5 8.8 2.8 1.4 2.9 4.8 1.4 0.6 3.4 2.5 3.2 4.2 6.2 7.5 5.0 2.9 1.9 5.5 11.8 10.6 0.3 1.3 0.4 1.2 2.5 11.0 2.1 2.1 0.0 2.2 1.5 0.7 3.8 3.5 1.3 7.0 3.2 4.8 0.8 11.5 1.9 2.1 1.1 6.3 3.0 2.6 17.4 0.3 0.8 0.0 1.5 0.4 0.9 22.8 1.8 1.4 0.2 0.1 5.5 0.9 12.7 3.8 0.1 2.8 4.2 1.4 1.9 0.3 0.4 1.3 0.0 0.6 2.9 0.2 9.7 8.8 0.2 2.2 1.2 1.1 0.0 1.2 0.0 1.5 0.5 0.1 3.1 0.0 5.6 0.9 15.1 7.6 18.5 0.6 12.7 0.5 7.6 1.0 0.0 15.6 12.9 0.3 0.8 4.4 12.5 0.4 0.0 3.4 0.0 0.3 8.9 9.5 8.2 9.0 5.6 2.0 0.0 0.3 0.0 0.0 1.2 0.1 1.2 0.2 0.0 0.3 2.1 0.0 0.2 0.0 0.0 0.2 0.4 0.5 0.5 6.1 12.8 8.5 8.8 6.2 7.5 11.8 10.6 11.0 7.0 11.5 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 FRMD3 "EPB41L4O, MGC20553" ENSG00000172159 "FERM domain containing 3" A2A2Y4 9 83242990-83538546 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 85.0;skeletal muscle: 81.2;tongue: 74.7" "Cell type enhanced" "Detected in many" "Bipolar cells: 108.6;Cardiomyocytes: 73.7;Cone photoreceptor cells: 79.2;Early spermatids: 121.9;Horizontal cells: 101.0;Late spermatids: 122.8;Sertoli cells: 72.3" "Cancer enriched" "Detected in many" 5 "thyroid cancer: 27.3" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 5 "classical monocyte: 2.0;intermediate monocyte: 3.4;neutrophil: 2.5;non-classical monocyte: 1.5" "Group enriched" "Detected in many" 7 "granulocytes: 2.5;monocytes: 3.4" "Cell line enhanced" "Detected in many" "HEL: 24.0;OE19: 49.2;RPMI-8226: 79.6;SCLC-21H: 28.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017285 Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 38: Heart - Muscle contraction" "Cluster 25: RPMI-8226 - Immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA017285: AB_2669569" "unprognostic (4.45e-2)" "unprognostic (1.85e-1)" "unprognostic (1.93e-1)" "unprognostic (6.44e-2)" "unprognostic (2.66e-1)" "unprognostic (2.23e-1)" "unprognostic (8.13e-2)" "unprognostic (3.93e-1)" "unprognostic (3.94e-2)" "unprognostic (1.06e-1)" "unprognostic (2.23e-1)" "unprognostic (5.87e-2)" "prognostic favorable (7.24e-4)" "unprognostic (3.12e-1)" "unprognostic (1.88e-1)" "prognostic favorable (1.79e-4)" "unprognostic (1.68e-3)" 9.4 7.3 6.6 2.0 5.5 5.4 6.7 4.3 6.8 3.0 12.0 5.5 2.9 2.7 15.7 2.5 2.2 2.5 85.0 6.3 7.7 14.9 0.7 4.0 1.3 10.1 8.5 1.4 1.6 20.6 4.2 14.8 7.3 2.8 6.6 21.6 2.9 7.8 81.2 2.1 6.7 3.5 7.6 7.2 2.8 9.9 9.9 1.1 7.1 74.7 0.5 4.6 2.6 5.4 0.0 4.3 3.8 0.3 0.7 0.2 0.3 4.1 0.3 0.1 0.0 0.5 5.2 0.9 4.7 1.9 0.9 0.2 0.2 0.0 0.0 0.2 0.2 24.0 4.8 2.8 0.2 0.0 0.3 1.0 0.1 0.0 0.2 0.2 2.7 0.1 0.1 0.1 4.9 0.7 0.0 0.1 0.4 49.2 7.2 0.1 3.0 79.6 6.2 10.1 28.4 13.8 1.4 0.3 0.9 0.6 1.7 0.8 4.4 0.2 0.6 0.1 2.9 0.4 0.3 0.0 0.9 7.6 2.8 0.0 2.0 0.0 0.2 3.4 0.4 0.3 0.1 0.0 0.2 0.4 0.0 0.0 2.5 0.3 1.5 0.4 0.0 6.0 6.6 5.5 4.3 6.8 6.3 7.7 10.1 8.5 7.3 7.6 9.9 5.4 38.4 22.4 1.1 6.2 0.4 1.0 1.0 0.6 0.6 108.6 2.6 1.9 73.7 15.7 1.8 1.8 79.2 0.4 0.2 28.9 17.6 2.8 121.9 2.8 1.4 25.8 1.2 0.8 37.9 2.0 1.2 8.8 2.0 3.9 0.0 0.4 4.2 0.3 0.8 101.0 70.0 38.3 0.0 4.4 0.6 122.8 2.1 8.3 0.0 27.2 4.2 3.9 1.0 10.1 16.0 2.3 10.0 4.9 0.0 1.6 43.6 12.4 3.2 7.0 72.3 66.6 50.7 4.1 1.4 0.2 1.3 0.1 0.9 29.8 2.4 2.3 FRS2 "FRS2A, FRS2alpha, SNT-1, SNT1" ENSG00000166225 "Fibroblast growth factor receptor substrate 2" Q8WU20 12 69470349-69579793 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 104.5;Oligodendrocyte precursor cells: 76.9;Oligodendrocytes: 89.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038323, HPA073385" Uncertain "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cell Junctions" "HPA038323: , HPA073385: " "unprognostic (9.15e-2)" "unprognostic (1.19e-1)" "unprognostic (1.25e-1)" "unprognostic (1.28e-1)" "unprognostic (8.50e-2)" "unprognostic (9.29e-2)" "unprognostic (1.51e-2)" "unprognostic (1.68e-1)" "unprognostic (1.22e-1)" "unprognostic (1.71e-1)" "unprognostic (1.33e-1)" "unprognostic (8.97e-2)" "unprognostic (2.34e-2)" "unprognostic (5.70e-3)" "unprognostic (3.80e-2)" "unprognostic (8.22e-2)" "unprognostic (6.66e-2)" 9.9 8.1 13.4 5.4 18.1 27.0 13.2 22.4 16.2 11.9 9.2 8.4 6.0 12.3 13.6 8.6 9.5 11.5 7.8 13.7 15.8 8.2 11.9 8.5 6.1 15.6 13.2 14.9 6.0 12.2 4.7 10.8 15.2 8.0 8.5 10.2 7.8 7.1 7.2 8.3 7.6 11.8 19.2 6.1 7.6 9.2 13.4 9.4 12.8 8.8 7.3 7.9 6.9 27.1 15.1 12.4 21.9 9.7 12.2 13.6 38.9 16.5 17.8 14.8 11.8 25.1 6.4 6.8 10.2 21.5 7.7 13.2 11.6 17.7 18.6 11.7 9.2 12.2 9.9 7.9 11.1 10.6 8.8 13.0 20.4 17.9 13.1 17.8 7.3 7.8 8.7 15.2 12.8 19.3 8.6 4.0 24.4 7.9 9.7 7.5 18.8 5.6 11.3 36.5 10.6 20.6 25.4 10.7 15.5 27.1 31.0 5.9 13.1 11.7 13.0 15.3 13.0 13.2 22.4 6.3 8.5 5.9 10.7 0.5 4.2 2.2 2.6 3.8 2.8 2.8 2.6 2.2 2.9 6.0 5.0 2.9 4.3 2.7 7.4 2.6 1.6 2.0 13.4 18.1 22.4 16.2 13.7 15.8 15.6 13.2 15.2 19.2 13.4 27.1 12.8 6.4 12.7 104.5 13.3 20.3 8.6 9.3 30.7 11.9 29.1 20.6 23.2 5.7 15.0 11.0 16.7 7.9 8.7 6.9 3.9 7.8 5.9 16.3 27.5 10.1 10.2 8.6 64.8 7.2 11.6 20.8 13.7 25.0 13.4 13.0 9.3 15.3 6.9 6.7 68.1 9.4 4.1 10.7 11.8 9.9 19.0 9.9 7.2 43.1 11.6 18.2 6.2 76.9 89.5 12.3 6.0 13.2 11.4 13.1 7.4 7.3 11.0 11.4 6.6 18.5 21.9 11.5 11.7 19.6 12.6 6.3 10.3 18.2 8.0 12.5 FSCN1 "FLJ38511, p55, SNL" ENSG00000075618 "Fascin actin-bundling protein 1" Q16658 7 5592816-5606655 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Granulosa cells: 256.5;Hofbauer cells: 274.2;monocytes: 1028.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "myeloid DC: 2.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "BEWO: 600.3;Hep G2: 464.9;K-562: 533.6;NB-4: 600.9;PC-3: 508.2;SH-SY5Y: 482.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000121, HPA005723, CAB035991, HPA050654" Enhanced Supported "Plasma membrane,Cytosol" NA Yes 4300000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 24: NB-4 - Immune response" "Cluster 3: Monocytes - Immune response regulation" Cytosol "Plasma membrane" "CAB000121: AB_2278596, CAB035991: , HPA005723: AB_1849159, HPA050654: AB_2681203" "unprognostic (1.91e-1)" "unprognostic (2.03e-2)" "unprognostic (3.12e-2)" "unprognostic (5.00e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (5.76e-4)" "unprognostic (2.16e-3)" "prognostic unfavorable (2.28e-4)" "unprognostic (6.31e-2)" "unprognostic (1.25e-1)" "unprognostic (3.27e-3)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.15e-7)" "unprognostic (1.21e-2)" "unprognostic (8.57e-2)" "unprognostic (1.05e-2)" "unprognostic (6.93e-3)" 27.5 39.7 41.5 31.1 62.2 8.3 24.9 26.3 57.2 33.7 10.7 12.1 4.4 19.7 0.7 69.4 15.6 7.6 15.8 39.4 28.2 17.3 8.3 27.6 14.5 49.4 42.7 47.7 5.5 2.3 20.2 27.9 22.8 10.3 1.7 3.4 23.8 2.4 7.3 56.3 12.6 5.7 20.9 55.6 9.3 42.5 79.0 9.0 25.6 2.1 8.3 20.4 41.6 77.1 62.3 139.3 91.2 326.3 34.8 65.4 600.3 144.2 62.4 24.2 26.1 98.5 15.6 1.3 172.0 63.5 24.3 231.3 52.2 229.9 2.1 70.6 28.7 4.8 142.0 464.9 18.0 0.2 13.9 40.8 66.6 46.1 37.2 40.4 118.3 0.7 533.6 0.9 31.6 6.9 2.0 600.9 238.4 4.2 508.2 140.0 22.3 2.3 34.9 5.9 73.1 482.4 121.0 2.6 5.3 58.5 3.9 38.4 246.4 167.4 289.3 99.1 151.0 0.9 0.8 0.7 107.8 0.6 317.2 0.0 0.8 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.7 41.5 62.2 26.3 57.2 39.4 28.2 49.4 42.7 22.8 20.9 79.0 77.1 90.0 3.2 4.1 1.6 8.3 181.2 26.7 75.1 189.5 9.4 32.3 44.3 10.4 1.5 13.4 1.8 0.0 6.7 10.8 3.9 0.0 12.8 14.3 8.0 37.8 120.6 42.1 28.0 12.1 5.1 110.8 48.9 10.7 10.1 16.5 256.5 84.6 0.8 274.2 0.0 10.9 5.4 8.2 28.0 136.1 12.3 25.4 27.4 51.6 23.4 1028.2 73.5 0.0 4.5 43.2 15.5 1.1 9.1 4.2 7.5 0.4 0.4 2.9 2.6 0.0 29.7 46.3 5.7 8.0 121.2 147.2 14.6 12.2 8.3 2.6 28.0 FTCD ENSG00000160282 "Formimidoyltransferase cyclodeaminase" O95954 21 46136262-46155579 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Histidine metabolism" "Lyase, Multifunctional enzyme, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "liver: 939.8" "Cell type enhanced" "Detected in many" "Cholangiocytes: 131.5;Early spermatids: 104.7;Hepatocytes: 444.9;Late spermatids: 124.3;Proximal tubular cells: 395.1" "Cancer enriched" "Detected in some" 8 "liver cancer: 87.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 30 "Hep G2: 92.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020073, HPA030928, HPA030929, HPA036114" Enhanced Approved "Plasma membrane,Cytosol" No NA 1600000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 85: Liver - Metabolism" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" Cytosol "Plasma membrane" "HPA020073: AB_1849005, HPA030928: AB_2673664, HPA030929: AB_2673665, HPA036114: AB_2674947" "unprognostic (1.71e-1)" "unprognostic (2.27e-1)" "unprognostic (4.62e-5)" "unprognostic (2.90e-2)" "unprognostic (1.13e-1)" "unprognostic (2.96e-1)" "prognostic favorable (1.70e-4)" "unprognostic (1.85e-1)" "unprognostic (2.67e-1)" "unprognostic (1.99e-1)" "prognostic favorable (6.78e-5)" "unprognostic (1.80e-1)" "prognostic favorable (5.78e-4)" "unprognostic (3.80e-2)" "unprognostic (3.60e-1)" "unprognostic (9.37e-2)" "unprognostic (2.10e-1)" 0.4 1.7 5.4 0.2 6.8 0.0 0.4 3.6 8.4 1.3 3.0 1.3 1.3 1.2 0.4 0.3 0.9 0.1 1.6 4.9 4.7 155.7 939.8 0.2 0.2 4.6 3.9 3.0 4.0 0.0 3.4 0.0 5.6 4.2 0.0 0.0 0.2 0.6 0.4 0.3 1.7 0.0 3.5 0.5 0.5 13.9 4.4 0.0 0.9 0.0 0.0 1.3 1.0 5.5 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.1 0.0 3.1 0.0 0.3 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.1 0.6 0.6 0.0 92.9 0.0 0.6 0.3 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.7 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.1 0.2 0.2 0.0 0.2 0.0 0.9 0.3 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.3 0.4 0.5 0.0 0.3 0.1 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 5.4 6.8 3.6 8.4 4.9 4.7 4.6 3.9 5.6 3.5 4.4 5.5 0.0 0.0 0.0 1.0 8.1 0.1 0.0 0.0 0.0 1.3 0.2 0.5 1.5 131.5 0.0 9.2 0.0 0.0 0.1 0.0 46.9 0.0 104.7 0.1 0.4 1.8 0.0 61.5 10.5 0.0 0.0 0.6 0.0 0.2 0.0 0.6 30.4 444.9 0.1 3.3 5.9 0.1 0.0 28.9 0.0 124.3 3.1 1.6 0.0 1.0 0.0 0.2 0.0 1.0 18.5 0.0 0.1 2.6 0.0 0.5 0.3 395.1 0.0 0.4 0.0 0.2 0.5 39.2 17.9 0.2 0.4 0.0 3.6 0.1 0.2 0.1 FUT2 "SE, Se2, SEC2, sej" ENSG00000176920 "Fucosyltransferase 2" Q10981 19 48695971-48705951 "Blood group antigen proteins, Enzymes, Metabolic proteins, Predicted membrane proteins" "Blood group antigen, Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 44.5;salivary gland: 66.2;stomach 1: 28.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 56.4;Club cells: 69.4;Distal enterocytes: 110.0;Gastric mucus-secreting cells: 83.6;Ionocytes: 57.0;Paneth cells: 75.5;Proximal enterocytes: 182.4;Undifferentiated cells: 62.9" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in some" 4 "cerebellum: 5.5" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in some" 7 "CAPAN-2: 63.6;OE19: 76.1" "Region enhanced" "Detected in some" "cerebellum: 2.3" "Low region specificity" "Detected in all" HPA014402 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA014402: AB_1849194" "unprognostic (2.95e-2)" "unprognostic (6.07e-2)" "unprognostic (2.80e-3)" "unprognostic (4.63e-3)" "unprognostic (2.63e-1)" "prognostic favorable (5.83e-4)" "unprognostic (6.30e-3)" "unprognostic (6.55e-3)" "unprognostic (1.58e-1)" "unprognostic (8.44e-2)" "unprognostic (7.89e-2)" "unprognostic (5.11e-1)" "unprognostic (4.04e-2)" "unprognostic (6.52e-3)" "unprognostic (1.73e-1)" "unprognostic (3.12e-1)" "unprognostic (2.87e-1)" 0.2 0.6 0.8 6.2 0.9 0.3 1.7 5.5 1.2 16.0 0.0 23.5 44.5 1.1 0.1 26.0 2.6 13.5 0.5 0.9 0.0 1.0 0.3 0.9 0.5 0.2 0.1 1.1 5.2 0.1 2.0 0.1 0.3 1.4 19.8 0.9 66.2 2.9 0.7 4.8 21.9 0.8 0.0 0.6 28.9 0.8 0.4 0.6 0.7 0.0 6.6 6.3 9.7 0.6 2.0 1.5 0.3 0.9 0.0 0.0 0.2 0.2 0.0 0.0 0.0 7.2 63.6 0.7 0.5 0.0 0.3 10.6 0.0 0.0 0.0 0.5 0.5 0.6 0.6 0.3 0.0 0.1 0.6 0.0 0.1 0.0 0.0 1.0 0.0 1.2 0.1 0.8 0.1 0.5 0.7 1.5 0.4 76.1 0.3 0.5 0.2 3.0 0.0 0.6 3.4 0.5 0.3 0.6 0.1 0.4 9.5 0.1 0.3 0.4 0.4 0.5 0.2 0.7 0.5 0.1 0.3 0.4 0.2 1.1 0.1 0.1 0.4 0.1 0.2 0.3 0.5 0.2 0.1 0.3 0.4 0.1 0.5 0.2 0.1 0.4 0.6 0.2 0.8 0.9 5.5 1.2 0.9 0.0 0.2 0.1 0.3 0.0 0.4 0.6 0.5 0.0 0.6 0.7 0.6 0.9 2.3 56.4 5.7 2.5 6.1 3.0 0.8 32.9 69.4 20.2 2.1 0.1 0.4 110.0 1.9 4.7 0.5 8.4 2.7 0.7 11.4 0.0 2.3 46.5 0.0 0.5 83.6 23.9 0.0 0.1 0.0 0.1 0.1 0.0 1.4 42.1 57.0 0.3 0.3 0.2 0.0 0.3 1.8 0.0 0.3 0.5 2.1 0.5 1.2 31.8 75.5 0.0 0.2 2.9 182.4 0.1 37.8 4.2 0.0 1.2 2.4 0.3 0.2 9.9 1.4 0.1 0.8 0.3 62.9 19.4 FXYD3 "MAT-8, PLML" ENSG00000089356 "FXYD domain containing ion transport regulator 3" Q14802 19 35115879-35124324 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Sodium/potassium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 1800.0" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 1870.8;Distal enterocytes: 5605.4;Intestinal goblet cells: 2165.8;Paneth cells: 3324.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 896.3;hTCEpi: 1603.2;OE19: 3112.0;RT4: 860.2;SK-BR-3: 830.8;WM-115: 589.7" HPA010856 Supported Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 37: Intestine - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA010856: AB_1078915" "unprognostic (2.18e-3)" "unprognostic (2.78e-2)" "unprognostic (8.37e-3)" "unprognostic (3.31e-3)" "unprognostic (6.38e-2)" "unprognostic (3.02e-1)" "unprognostic (2.64e-3)" "unprognostic (1.60e-1)" "unprognostic (3.59e-1)" "unprognostic (1.03e-1)" "unprognostic (2.32e-2)" "unprognostic (3.88e-1)" "prognostic unfavorable (1.15e-6)" "unprognostic (4.17e-2)" "unprognostic (2.08e-1)" "unprognostic (5.06e-2)" "unprognostic (7.69e-3)" 5.1 1.1 7.3 59.5 7.4 1.3 225.2 7.1 7.9 168.0 7.5 1466.2 102.7 13.2 15.2 685.3 104.3 100.5 5.8 7.1 6.5 12.0 2.0 150.2 0.8 8.0 7.3 1.8 64.3 0.1 24.7 84.9 6.8 512.1 1800.0 45.4 569.1 33.3 2.1 568.3 308.9 35.7 6.7 0.6 572.4 0.6 7.0 18.7 1.5 0.1 163.3 295.6 395.8 7.4 166.3 0.0 0.0 0.4 0.6 0.4 150.5 0.0 0.0 0.0 0.0 6.0 235.3 0.3 0.5 0.0 1.3 896.3 0.1 339.5 0.0 0.1 0.3 1.0 7.7 0.6 0.1 0.1 0.6 0.0 1603.2 0.0 0.7 0.1 0.1 0.1 0.1 1.1 0.0 304.5 0.8 2.2 0.8 3112.0 1.4 0.8 0.4 1.2 0.0 860.2 190.2 2.1 1.0 830.8 61.8 2.3 155.9 0.2 0.0 0.3 0.6 0.9 0.7 0.1 0.4 0.7 1.0 0.3 589.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.7 0.0 0.1 7.3 7.4 7.1 7.9 7.1 6.5 8.0 7.3 6.8 6.7 7.0 7.4 3.1 762.8 262.6 0.3 11.1 576.9 792.9 1870.8 340.4 2.9 557.5 515.7 1.3 201.6 1026.4 134.3 0.0 883.5 8.3 5605.4 1.9 35.6 0.4 180.1 29.5 19.7 974.3 2.7 0.1 708.4 138.1 20.3 356.8 194.1 22.3 0.0 0.0 0.9 81.4 1.7 0.0 2165.8 587.9 0.0 68.3 0.0 0.0 15.6 412.6 0.0 1.6 422.1 0.0 0.0 0.6 556.5 3324.0 0.0 6.5 1041.7 1693.0 0.5 1627.1 13.3 0.0 0.5 66.5 0.2 0.2 541.1 865.5 1512.1 17.9 0.0 1499.3 1509.9 FYB1 "ADAP, FYB, FYB-120/130, SLAP-130" ENSG00000082074 "FYN binding protein 1" O15117 5 39105252-39274528 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 53.0;lymphoid tissue: 112.8" "Cell type enhanced" "Detected in many" "dendritic cells: 142.9;Extravillous trophoblasts: 88.7;Hofbauer cells: 157.0;Macrophages: 104.2;T-cells: 119.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 1670.8" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "HEL: 61.5;JURKAT: 211.9;MOLT-4: 212.9;REH: 61.3;U-937: 81.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "CAB025336, HPA026796, HPA067427" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 6200000 "Cluster 1: Neutrophils - Mixed function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB025336: , HPA026796: AB_10964126, HPA067427: " "unprognostic (5.65e-2)" "unprognostic (2.92e-2)" "unprognostic (1.56e-2)" "unprognostic (6.26e-2)" "unprognostic (4.08e-1)" "unprognostic (3.29e-2)" "unprognostic (2.60e-1)" "unprognostic (1.97e-1)" "unprognostic (1.24e-1)" "unprognostic (5.63e-2)" "unprognostic (5.35e-2)" "unprognostic (3.21e-1)" "prognostic unfavorable (2.24e-4)" "unprognostic (2.40e-1)" "unprognostic (4.14e-2)" "unprognostic (8.99e-2)" "unprognostic (1.51e-1)" 10.2 5.8 5.7 82.5 5.5 53.0 5.1 6.3 9.3 6.6 7.4 10.0 9.1 3.8 10.5 5.7 3.6 16.8 2.4 5.4 7.9 5.0 13.6 17.6 85.8 16.7 19.1 2.7 1.8 2.1 1.5 17.9 15.8 4.2 11.0 0.5 7.4 3.0 1.2 2.0 15.0 11.6 9.3 73.0 12.2 3.3 13.3 112.8 2.6 2.7 63.0 17.1 1.8 13.9 0.2 4.2 0.0 0.0 0.5 0.0 21.1 0.1 1.2 0.3 0.4 0.4 0.3 0.3 0.0 0.0 8.0 16.4 0.0 0.3 0.1 0.3 0.0 61.5 0.0 0.1 0.0 23.3 18.6 0.3 0.4 0.0 0.4 0.1 0.0 211.9 0.0 0.0 0.0 0.0 212.9 13.5 0.2 0.1 0.1 61.3 0.0 0.3 1.0 3.5 0.1 0.0 0.1 0.5 6.5 1.4 0.0 5.2 0.0 0.0 0.2 0.2 0.2 0.4 0.0 4.5 0.0 81.4 0.2 151.3 359.0 354.6 76.3 406.5 52.9 1.8 216.7 134.5 127.6 1.3 271.7 169.8 1670.8 89.9 483.9 30.8 231.5 400.1 5.7 5.5 6.3 9.3 5.4 7.9 16.7 19.1 15.8 9.3 13.3 13.9 4.4 16.0 24.7 0.0 6.2 0.0 0.0 0.0 0.0 0.0 3.2 7.6 0.0 0.0 5.6 14.7 0.0 28.8 142.9 0.0 9.8 0.4 0.0 0.7 1.1 4.3 0.0 0.0 0.0 0.0 88.7 3.8 0.0 1.0 15.2 0.1 0.0 0.0 157.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 104.2 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 31.5 0.0 0.0 35.9 3.6 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 40.2 119.3 0.1 0.0 0.0 FYN "MGC45350, SLK, SYN" ENSG00000010810 "FYN proto-oncogene, Src family tyrosine kinase" P06241 6 111660332-111873452 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Host-virus interaction, Immunity" "Developmental protein, Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 382.6;dendritic cells: 291.6;NK-cells: 228.6;Oligodendrocyte precursor cells: 342.8;Proximal tubular cells: 212.2;T-cells: 275.8" "Cancer enhanced" "Detected in all" "glioma: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in all" 16 "NK-cells: 69.0;T-cells: 174.8" "Cell line enhanced" "Detected in many" "U-2197: 538.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005034, CAB018387, HPA023887, HPA063770" Approved Enhanced "Plasma membrane,Cytosol" NA NA 820000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "CAB005034: AB_562117, CAB018387: AB_627642, HPA023887: AB_1849226, HPA063770: AB_2685119" "unprognostic (8.62e-3)" "unprognostic (8.25e-2)" "unprognostic (2.11e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (2.43e-2)" "prognostic favorable (1.84e-4)" "unprognostic (4.60e-2)" "unprognostic (2.89e-2)" "unprognostic (2.92e-1)" "prognostic favorable (4.78e-4)" "unprognostic (1.43e-1)" "prognostic unfavorable (1.43e-4)" "unprognostic (6.95e-2)" "unprognostic (3.10e-1)" "unprognostic (6.62e-3)" "unprognostic (2.40e-1)" 76.6 10.8 117.1 52.4 106.4 32.3 46.8 83.8 104.3 45.5 33.3 32.9 16.4 45.6 33.8 16.0 51.4 32.1 40.5 102.1 121.5 23.9 20.4 63.5 108.9 136.3 104.9 28.8 8.5 18.7 22.9 29.7 107.0 17.6 15.6 26.9 12.9 12.5 12.3 41.5 47.1 38.0 109.9 71.9 29.3 16.5 105.7 86.1 45.7 18.3 67.6 48.4 33.4 109.8 10.4 1.5 178.6 30.2 133.4 81.4 3.2 29.1 90.8 24.2 42.9 1.3 1.6 21.0 18.3 56.1 21.0 1.3 25.8 39.9 46.8 0.7 66.5 57.0 13.6 2.7 78.7 19.5 19.0 78.8 59.1 90.5 76.8 62.9 99.5 99.6 4.9 140.3 86.8 1.5 92.7 17.9 26.0 3.3 18.0 29.1 24.0 1.4 0.0 9.1 124.6 50.7 5.7 2.4 124.7 39.6 1.3 57.0 63.9 72.3 13.5 538.7 18.5 20.0 19.7 32.5 136.0 44.3 128.9 1.1 6.4 0.2 137.0 5.6 174.8 4.8 83.9 152.7 7.4 6.4 27.9 72.3 3.0 69.0 4.2 4.3 79.2 51.5 117.1 106.4 83.8 104.3 102.1 121.5 136.3 104.9 107.0 109.9 105.7 109.8 87.8 0.0 8.3 382.6 26.0 17.1 2.5 0.6 1.8 57.2 2.9 6.9 11.3 14.3 2.1 7.3 0.0 2.7 291.6 1.2 17.6 9.3 3.7 5.6 51.7 70.3 13.2 20.9 118.7 1.0 2.4 61.9 17.9 4.9 52.0 20.9 76.4 60.3 3.0 47.1 127.6 3.8 2.0 35.8 96.1 3.2 26.4 42.7 37.4 88.1 64.5 89.1 228.6 342.8 162.3 9.7 0.1 7.2 96.2 3.9 17.7 212.2 4.4 8.3 13.1 48.8 32.9 3.9 8.6 0.7 13.4 52.0 275.8 71.1 2.9 1.1 FZD4 "CD344, EVR1" ENSG00000174804 "Frizzled class receptor 4" Q9ULV1 11 86945679-86955395 "CD markers, Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Wnt signaling pathway" "Developmental protein, G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 120.1" "Cell type enhanced" "Detected in many" "Adipocytes: 83.0;Collecting duct cells: 36.8;Endothelial cells: 51.2;Hepatic stellate cells: 99.6;Sertoli cells: 32.9" "Cancer enhanced" "Detected in all" "renal cancer: 22.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 63.6;Hep G2: 85.2;HSkMC: 46.0;HUVEC TERT2: 93.6;TIME: 46.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042328, HPA074833" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA042328: AB_10962494, HPA074833: AB_2686716" "unprognostic (6.49e-2)" "unprognostic (1.49e-2)" "unprognostic (1.03e-1)" "unprognostic (1.03e-1)" "unprognostic (5.87e-2)" "unprognostic (5.51e-2)" "unprognostic (1.82e-1)" "unprognostic (6.97e-2)" "unprognostic (3.33e-2)" "unprognostic (3.79e-2)" "unprognostic (1.36e-2)" "unprognostic (2.22e-1)" "prognostic favorable (8.60e-5)" "unprognostic (1.05e-2)" "unprognostic (9.96e-2)" "unprognostic (9.22e-2)" "unprognostic (1.97e-1)" 120.1 9.5 6.7 5.8 6.2 0.3 55.6 5.1 7.3 12.5 7.8 14.9 2.8 12.2 7.6 6.5 16.3 11.5 27.4 5.6 5.9 27.1 14.6 32.9 6.2 6.5 6.3 12.9 9.5 6.4 8.7 11.7 7.0 12.5 6.3 1.1 12.2 30.2 31.5 5.9 8.8 13.4 5.6 14.1 14.1 5.1 8.5 3.9 18.1 40.6 4.6 10.5 9.5 5.9 1.3 1.1 2.7 5.2 63.6 16.5 3.7 8.4 7.6 3.2 3.3 7.1 0.9 0.0 1.8 2.6 4.4 2.8 3.1 1.3 2.5 0.2 2.1 2.8 2.3 85.2 18.9 0.0 0.1 46.0 0.5 2.8 0.5 7.5 93.6 0.1 3.9 0.4 2.2 2.2 0.0 0.0 3.9 7.5 18.8 0.1 4.8 0.2 9.0 13.7 0.6 0.8 3.5 1.0 1.4 5.6 12.0 0.0 46.3 7.8 5.1 9.2 1.7 0.4 1.3 0.0 1.0 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 6.7 6.2 5.1 7.3 5.6 5.9 6.5 6.3 7.0 5.6 8.5 5.9 83.0 0.0 1.3 9.8 0.5 1.5 0.5 1.3 2.2 0.7 5.5 3.2 8.3 7.2 2.0 36.8 10.4 0.2 0.5 1.0 3.9 0.5 0.7 0.4 2.7 51.2 0.0 2.7 8.1 1.6 0.2 17.7 4.1 0.5 0.0 9.1 99.6 14.1 0.2 0.0 3.4 1.3 0.0 6.7 1.8 2.2 9.3 0.6 0.0 10.3 0.0 0.2 2.1 3.0 0.7 1.0 0.1 6.8 0.3 1.4 0.7 9.4 2.1 0.2 32.9 14.4 26.6 0.3 3.2 1.3 0.6 0.3 0.4 16.6 1.1 0.2 GABRA1 EJM5 ENSG00000022355 "Gamma-aminobutyric acid type A receptor subunit alpha1" P14867 5 161847063-161899981 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 30 "brain: 55.1;retina: 17.8" "Group enriched" "Detected in some" 11 "Bipolar cells: 198.0;Excitatory neurons: 220.5;Inhibitory neurons: 215.2" "Cancer enriched" "Detected in single" 5 "glioma: 1.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022502, HPA029363, HPA055746" Enhanced Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Brain - Smell perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "CAB022502: , HPA029363: , HPA055746: AB_2682904" "unprognostic (2.58e-2)" "unprognostic (4.78e-3)" "unprognostic (1.84e-1)" "unprognostic (3.31e-1)" "unprognostic (2.43e-1)" 0.0 1.2 6.7 0.0 11.1 0.0 0.0 24.8 55.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 7.7 21.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 17.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.1 14.3 0.6 0.0 0.0 0.2 0.0 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.7 11.1 24.8 55.1 7.7 21.7 0.0 0.0 0.0 0.0 14.3 24.0 0.0 0.0 0.0 17.6 0.0 0.0 0.0 0.0 0.0 198.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.8 0.0 0.0 0.1 0.0 0.0 220.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.4 215.2 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 17.8 0.0 3.5 0.0 8.0 16.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 9.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GABRA2 ENSG00000151834 "Gamma-aminobutyric acid type A receptor subunit alpha2" P47869 4 46243548-46475230 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 31.5;epididymis: 8.8" "Group enriched" "Detected in many" 5 "Astrocytes: 425.4;Excitatory neurons: 156.2;Inhibitory neurons: 111.6" "Cancer enhanced" "Detected in some" "colorectal cancer: 0.6;glioma: 0.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "U-2 OS: 4.2;U-87 MG: 2.1;WM-115: 2.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029363, CAB079061" Supported Uncertain "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 9: U-2 OS - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079061: , HPA029363: " "unprognostic (2.03e-2)" "unprognostic (2.77e-1)" "unprognostic (2.45e-4)" "unprognostic (6.87e-3)" "unprognostic (2.65e-1)" "unprognostic (2.08e-1)" "unprognostic (1.01e-1)" "unprognostic (4.09e-1)" "unprognostic (6.90e-3)" "unprognostic (8.83e-2)" "unprognostic (2.22e-5)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.67e-1)" "unprognostic (3.04e-2)" 1.2 0.3 20.2 0.4 29.9 0.2 1.3 2.6 31.5 0.5 0.0 3.0 0.9 0.4 8.8 0.7 0.0 0.5 0.2 29.4 16.0 6.3 0.4 0.1 0.3 0.3 1.9 0.7 0.1 0.0 0.5 0.4 0.0 0.1 2.1 2.4 0.2 0.7 0.1 0.2 6.0 0.2 1.3 1.2 0.5 0.5 13.8 0.4 0.1 0.1 0.4 0.2 0.7 8.8 0.1 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.1 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.0 0.1 0.4 0.6 0.0 0.0 0.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 4.2 0.2 0.0 0.2 0.6 0.0 2.1 0.1 2.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 20.2 29.9 2.6 31.5 29.4 16.0 0.3 1.9 0.0 1.3 13.8 8.8 4.9 0.0 0.0 425.4 0.0 0.1 0.0 0.0 1.2 15.3 0.2 0.0 0.6 0.0 0.0 40.5 4.2 0.0 0.0 23.1 3.9 0.0 9.1 1.2 31.7 1.0 31.8 0.0 156.2 0.0 0.0 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 111.6 3.4 0.0 0.0 0.0 17.1 0.6 0.1 1.8 16.9 0.0 0.2 0.0 13.0 5.5 0.0 4.7 0.0 0.0 0.0 38.1 0.1 0.0 1.1 0.0 0.0 0.2 0.0 1.3 0.0 0.1 0.0 0.1 0.0 2.7 0.0 GABRA3 ENSG00000011677 "Gamma-aminobutyric acid type A receptor subunit alpha3" P34903 X 152166234-152451315 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 15.5;choroid plexus: 16.3;retina: 9.0" "Cell type enhanced" "Detected in some" "Excitatory neurons: 70.3;Hofbauer cells: 16.2;Inhibitory neurons: 22.2;Oligodendrocyte precursor cells: 58.3" "Cancer enriched" "Detected in many" 7 "testis cancer: 16.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 9.9;HMC-1: 8.4;Karpas-707: 14.4;PC-3: 8.4;U-266/70: 7.7;U-266/84: 13.6;U-87 MG: 8.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000839, HPA029363" Approved Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 2: Karpas-707 - Immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA000839: AB_1078929, HPA029363: " "unprognostic (9.63e-3)" "unprognostic (2.04e-1)" "unprognostic (2.02e-1)" "unprognostic (1.18e-2)" "unprognostic (7.07e-2)" "unprognostic (5.42e-2)" "unprognostic (2.34e-6)" "unprognostic (1.24e-1)" "unprognostic (2.70e-1)" "unprognostic (2.39e-2)" "unprognostic (2.63e-2)" "unprognostic (1.73e-1)" "unprognostic (7.29e-6)" "unprognostic (7.42e-3)" "unprognostic (6.20e-2)" "unprognostic (8.13e-2)" 0.0 0.0 10.0 0.0 13.7 0.0 0.0 0.0 13.2 0.9 16.3 0.1 0.1 0.3 0.0 0.4 0.0 0.0 0.0 9.6 15.5 0.0 0.0 0.0 0.0 0.9 4.0 0.0 0.0 0.0 0.6 2.9 3.0 0.1 0.0 9.0 0.1 0.6 0.0 0.2 0.1 0.0 0.6 0.0 0.0 0.7 11.2 0.0 0.0 0.0 0.1 0.4 0.2 2.7 0.0 0.8 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 9.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 4.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 14.4 0.0 0.0 0.0 0.0 2.6 6.4 8.4 0.0 0.0 0.0 0.0 0.0 0.2 5.2 0.0 5.3 0.4 0.3 0.1 1.3 0.1 5.3 7.0 0.3 1.6 7.7 13.6 0.0 8.4 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.0 13.7 0.0 13.2 9.6 15.5 0.9 4.0 3.0 0.6 11.2 2.7 0.0 0.0 0.0 3.6 0.0 0.0 0.1 0.0 0.6 1.2 0.0 0.0 0.3 0.0 0.0 0.0 2.1 3.2 0.0 0.0 0.0 0.0 0.2 0.0 1.1 0.1 0.0 0.0 70.3 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.0 16.2 1.7 22.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 4.7 0.0 3.0 0.0 58.3 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.5 1.2 0.9 0.0 1.9 0.0 0.0 0.0 0.5 GABRA5 ENSG00000186297 "Gamma-aminobutyric acid type A receptor subunit alpha5" P31644 15 26866911-26949208 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Ion transport, Transport" "Chloride channel, Ion channel, Ligand-gated ion channel, Receptor" "Disease variant, Epilepsy, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 12 "brain: 111.0" "Group enriched" "Detected in some" 4 "Excitatory neurons: 27.6;Inhibitory neurons: 14.1" "Cancer enhanced" "Detected in some" "glioma: 0.8" "Group enriched" "Detected in many" 4 "amygdala: 52.0;basal ganglia: 73.5;cerebral cortex: 98.6;hippocampal formation: 111.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 10 "A549: 35.3;HAP1: 12.0;NTERA-2: 16.2;U-2 OS: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA029363, HPA077031, CAB079022" Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 5: NTERA-2 - Transcription" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "CAB079022: , HPA029363: , HPA077031: AB_2686825" "unprognostic (6.33e-2)" "unprognostic (8.94e-3)" "unprognostic (1.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.81e-1)" "unprognostic (3.75e-1)" "unprognostic (9.50e-3)" "unprognostic (2.57e-1)" "unprognostic (7.63e-2)" "unprognostic (8.50e-2)" "unprognostic (1.44e-2)" 0.0 0.0 52.0 0.1 73.5 0.0 0.0 0.0 98.6 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.5 111.0 7.2 0.1 0.1 0.0 0.0 0.0 3.0 0.0 0.1 0.7 0.5 0.0 0.0 0.2 0.0 1.6 0.0 0.1 0.0 0.0 0.1 0.6 0.0 0.0 1.2 0.7 12.0 9.0 0.1 0.1 0.3 0.0 0.0 19.6 0.0 35.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.8 0.0 0.0 12.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 16.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.5 0.0 0.1 0.2 1.8 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 52.0 73.5 0.0 98.6 111.0 7.2 0.0 3.0 0.0 0.0 12.0 19.6 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 27.6 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.1 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.0 0.8 0.0 1.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 2.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 GADL1 ENSG00000144644 "Glutamate decarboxylase like 1" Q6ZQY3 3 30726200-30894765 "Enzymes, Predicted intracellular proteins" "Decarboxylase, Lyase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "skeletal muscle: 25.8;tongue: 11.3" "Cell type enhanced" "Detected in some" "Bipolar cells: 1.4;Club cells: 1.3;Collecting duct cells: 1.8;Fibroblasts: 5.9;Late spermatids: 1.8;Skeletal myocytes: 1.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 4.7;TIME: 2.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA039160, HPA040229" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 2: Karpas-707 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA039160: AB_10796222, HPA040229: AB_10796118" "unprognostic (4.96e-2)" "unprognostic (1.30e-2)" "unprognostic (9.83e-2)" "unprognostic (1.39e-2)" "unprognostic (5.60e-2)" "unprognostic (7.32e-2)" "unprognostic (5.05e-3)" "unprognostic (8.37e-2)" "unprognostic (1.23e-2)" "unprognostic (2.02e-3)" "unprognostic (1.63e-1)" "unprognostic (1.98e-5)" "unprognostic (8.81e-2)" "unprognostic (4.54e-2)" "unprognostic (4.39e-1)" "unprognostic (1.06e-1)" 0.3 0.4 2.2 0.4 2.1 1.2 0.4 2.6 2.5 0.1 0.1 0.2 0.2 0.3 0.6 0.6 0.2 0.3 0.6 1.8 0.8 0.7 0.3 0.3 0.4 0.9 0.5 0.6 0.4 0.2 0.2 0.3 0.9 0.6 0.2 1.7 0.4 0.1 25.8 0.9 0.2 0.2 0.1 0.6 0.3 0.5 1.0 0.1 0.9 11.3 0.3 0.2 0.0 2.3 0.4 0.0 0.2 0.4 0.3 0.1 0.5 0.2 0.1 0.0 0.0 0.5 0.5 0.4 0.2 0.0 0.2 0.3 4.7 0.1 0.1 0.6 0.1 0.5 0.8 0.2 0.0 0.3 1.3 0.1 0.1 0.2 0.1 0.4 0.1 0.3 0.5 1.7 0.2 0.3 0.2 0.5 0.5 0.1 0.1 0.7 0.9 0.4 0.2 0.6 0.5 0.3 0.2 0.3 1.3 0.3 0.4 0.3 2.4 0.6 0.5 0.8 0.2 0.6 0.3 0.3 0.2 0.2 0.6 0.2 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.1 0.0 2.2 2.1 2.6 2.5 1.8 0.8 0.9 0.5 0.9 0.1 1.0 2.3 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.6 0.0 1.3 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.3 0.0 0.0 0.5 0.0 0.0 5.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.3 1.8 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.6 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 GAPVD1 "DKFZP434C212, KIAA1521" ENSG00000165219 "GTPase activating protein and VPS9 domains 1" Q14C86 9 125261794-125367207 "Predicted intracellular proteins" Endocytosis "GTPase activation, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029386, HPA029387, HPA074882" Uncertain Enhanced "Plasma membrane,Cytosol" NA NA 46000 "Cluster 18: Basophils - Vesicular transport" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Cytosol "HPA029386: AB_10599604, HPA029387: AB_10600311, HPA074882: " "unprognostic (8.43e-3)" "unprognostic (3.84e-2)" "unprognostic (3.53e-1)" "unprognostic (1.97e-1)" "unprognostic (5.43e-2)" "unprognostic (4.04e-2)" "unprognostic (7.08e-2)" "unprognostic (1.31e-2)" "unprognostic (7.56e-2)" "unprognostic (1.23e-1)" "unprognostic (2.77e-1)" "unprognostic (1.27e-1)" "unprognostic (2.54e-3)" "unprognostic (2.77e-1)" "unprognostic (4.19e-2)" "unprognostic (1.67e-2)" "unprognostic (5.82e-2)" 12.3 9.8 8.1 12.2 11.1 23.0 12.0 11.7 9.4 12.2 13.1 10.3 8.0 11.1 9.8 17.0 10.7 10.3 9.7 8.4 8.8 13.0 11.2 15.7 12.6 9.8 8.9 12.1 10.6 18.7 8.2 18.4 10.0 10.5 9.8 16.5 9.3 12.4 19.1 14.7 9.2 13.3 10.1 12.7 9.6 26.8 9.7 14.1 18.9 18.7 15.0 12.2 10.1 14.2 22.8 23.2 21.8 20.0 26.2 28.6 30.5 25.0 28.9 29.0 24.2 37.0 15.9 30.2 13.3 31.9 28.7 44.9 46.2 25.8 31.1 28.1 27.1 34.6 53.1 18.4 30.1 41.4 56.0 20.1 25.2 34.6 27.2 18.7 35.0 23.8 68.8 16.3 24.3 33.2 31.2 18.0 21.6 41.2 26.2 27.2 47.6 29.1 16.2 23.2 28.8 18.9 36.9 32.6 20.0 21.7 40.9 20.9 36.1 19.9 14.3 35.7 27.2 20.7 42.3 29.9 24.1 22.9 26.4 25.6 15.9 19.6 13.0 15.4 12.7 10.0 13.5 14.6 15.4 9.5 13.3 14.3 19.5 15.2 19.8 5.8 11.8 11.3 8.1 11.1 11.7 9.4 8.4 8.8 9.8 8.9 10.0 10.1 9.7 14.2 30.0 109.0 58.0 35.6 28.3 31.9 18.2 23.0 32.5 29.9 21.0 17.5 66.8 14.3 34.8 27.6 52.1 42.3 20.7 16.6 9.8 16.2 58.3 35.7 30.7 26.8 12.6 77.0 68.4 19.3 23.7 26.2 18.3 31.4 15.8 27.6 21.4 15.2 27.6 35.3 69.7 15.9 10.2 25.4 28.5 17.7 23.0 30.5 17.8 51.5 31.2 22.8 18.6 45.2 62.7 22.3 13.9 24.0 26.5 20.0 15.4 16.1 57.2 39.1 19.7 27.8 32.0 85.6 34.5 32.3 36.9 67.0 28.3 32.5 17.0 29.8 GAS2L1 GAR22 ENSG00000185340 "Growth arrest specific 2 like 1" Q99501 22 29306582-29312785 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatic stellate cells: 84.6;Late spermatids: 89.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 77.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019858 Approved Approved "Plasma membrane,Cell Junctions" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Cell Junctions" "HPA019858: AB_1849486" "unprognostic (3.66e-1)" "unprognostic (5.22e-2)" "unprognostic (1.38e-1)" "unprognostic (4.95e-3)" "unprognostic (1.77e-1)" "unprognostic (1.11e-1)" "unprognostic (1.84e-3)" "unprognostic (8.99e-2)" "unprognostic (1.28e-1)" "unprognostic (6.05e-2)" "unprognostic (1.90e-1)" "unprognostic (1.21e-1)" "prognostic favorable (8.44e-4)" "unprognostic (4.23e-2)" "unprognostic (9.04e-2)" "unprognostic (1.32e-1)" "unprognostic (1.19e-2)" 22.6 36.3 46.7 5.5 41.8 6.5 22.4 39.4 58.5 16.2 30.4 25.8 18.1 18.4 5.3 34.3 16.5 4.2 33.5 45.4 37.8 21.0 18.6 19.3 2.3 50.0 43.3 8.9 14.4 6.6 22.1 4.1 42.2 22.2 2.0 4.0 24.7 16.9 6.5 52.8 17.8 4.4 41.8 29.1 27.4 51.3 47.3 1.1 15.6 3.9 1.8 17.6 19.6 37.4 20.4 23.1 3.5 14.5 5.5 5.2 22.6 29.7 8.9 12.3 6.4 10.6 14.2 0.1 13.1 15.9 12.9 60.5 6.0 16.8 2.2 27.6 2.9 26.5 19.9 7.5 7.0 0.2 17.8 5.6 11.5 11.9 4.7 8.9 16.5 26.2 12.8 4.1 9.0 17.2 0.5 14.8 5.3 13.5 51.6 0.6 10.3 1.7 7.5 12.8 1.2 19.0 23.0 30.3 17.0 4.4 30.2 4.1 35.5 77.0 53.0 34.6 30.3 0.3 0.4 0.3 34.1 1.0 19.3 0.0 0.5 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.2 46.7 41.8 39.4 58.5 45.4 37.8 50.0 43.3 42.2 41.8 47.3 37.4 34.5 6.4 1.7 28.1 0.4 28.2 7.0 12.3 21.6 3.6 24.0 18.4 5.6 14.3 8.3 1.8 6.2 24.8 0.8 13.4 7.9 12.2 33.8 19.2 9.2 26.2 1.8 19.6 14.8 6.7 14.3 12.0 9.2 10.0 1.3 28.9 84.6 12.0 14.1 13.5 11.4 5.1 20.3 14.5 23.0 89.7 9.6 37.6 12.4 7.5 7.6 5.4 0.0 4.0 4.0 10.2 7.2 11.7 0.2 6.1 41.7 10.1 4.3 20.9 39.5 35.3 23.5 5.4 12.4 27.9 32.4 6.7 2.2 17.8 11.8 4.6 GAS8 "DRC4, GAS11" ENSG00000141013 "Growth arrest specific 8" O95995 16 90019629-90044975 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 198.3;Late spermatids: 277.8;Respiratory ciliated cells: 82.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "MCF7: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041311, HPA048238" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 34: Spermatids - Unknown function" Cytosol "Plasma membrane" "HPA041311: AB_2677402, HPA048238: AB_2680324" "unprognostic (2.23e-3)" "unprognostic (1.26e-1)" "unprognostic (1.73e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.73e-1)" "unprognostic (3.91e-1)" "unprognostic (1.96e-1)" "unprognostic (1.82e-1)" "unprognostic (1.16e-1)" "unprognostic (4.47e-1)" "prognostic favorable (7.67e-4)" "unprognostic (3.06e-2)" "prognostic favorable (1.09e-7)" "unprognostic (1.98e-1)" "unprognostic (2.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.19e-2)" 5.2 10.3 9.5 2.8 9.7 1.4 6.3 10.0 14.3 7.8 12.3 7.7 2.6 6.5 10.1 8.4 18.9 6.1 15.4 9.5 9.9 13.8 5.5 7.1 2.8 10.3 10.0 8.9 10.5 16.3 14.1 2.1 10.1 7.3 3.0 5.0 11.4 8.6 15.1 4.5 3.9 4.4 10.3 3.4 8.2 16.8 10.9 2.5 12.5 10.0 2.0 6.3 5.8 10.2 17.9 14.5 1.8 8.5 7.8 6.2 14.3 3.6 8.8 13.9 4.1 14.1 13.0 1.0 9.1 7.1 8.4 17.8 5.9 9.9 3.3 0.0 10.7 3.7 9.0 16.2 8.7 2.2 2.8 7.9 6.0 10.4 4.7 6.3 8.3 5.8 14.3 2.1 6.1 41.9 2.5 9.9 11.6 11.3 7.4 0.7 15.7 1.0 17.4 8.5 14.6 10.7 18.4 9.7 21.0 1.6 19.6 8.4 6.2 8.6 10.3 4.7 8.3 3.4 5.4 0.0 21.3 2.7 15.1 1.7 1.2 1.4 0.7 2.0 0.7 0.4 1.0 1.4 1.7 0.8 0.8 0.7 1.5 0.0 1.3 1.9 1.6 0.8 9.5 9.7 10.0 14.3 9.5 9.9 10.3 10.0 10.1 10.3 10.9 10.2 5.9 22.4 11.3 20.5 3.1 1.1 4.7 7.0 5.7 11.9 14.1 10.8 7.9 25.8 13.4 22.0 20.9 3.0 0.7 5.9 13.7 17.1 198.3 45.5 7.1 5.8 6.0 3.0 27.5 10.9 3.6 5.5 12.2 10.0 2.5 16.1 7.1 4.8 4.1 26.9 24.6 6.3 8.2 0.8 1.4 277.8 14.0 2.3 5.4 1.9 1.3 12.4 0.0 13.0 6.0 10.0 4.6 7.5 1.1 5.8 5.3 30.9 82.3 28.0 6.6 6.7 9.5 28.7 11.9 7.2 2.6 1.6 1.6 25.2 5.3 5.8 GBP4 Mpa2 ENSG00000162654 "Guanylate binding protein 4" Q96PP9 1 89181144-89198942 "Plasma proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 84.4;Endothelial cells: 81.2;Hepatic stellate cells: 92.4;Theca cells: 122.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "CAPAN-2: 12.1;HDLM-2: 9.9;HEL: 13.0;REH: 11.1;RT4: 18.3;U-266/70: 16.0" "HPA030101, HPA062039" Enhanced Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 16: Immune cells - Immune response" "Cluster 15: RT4 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Golgi apparatus" "Plasma membrane" "HPA030101: AB_10601654, HPA062039: " "unprognostic (1.32e-2)" "unprognostic (3.89e-3)" "unprognostic (1.02e-2)" "unprognostic (1.07e-3)" "unprognostic (3.22e-1)" "unprognostic (9.93e-3)" "unprognostic (5.65e-2)" "unprognostic (1.09e-1)" "unprognostic (3.22e-1)" "prognostic favorable (9.29e-5)" "unprognostic (1.91e-3)" "unprognostic (3.38e-1)" "prognostic unfavorable (1.30e-5)" "unprognostic (1.22e-1)" "unprognostic (3.91e-2)" "unprognostic (2.68e-2)" "unprognostic (2.02e-3)" 11.3 5.2 4.0 29.5 3.9 6.6 6.7 4.4 4.8 4.2 2.6 6.6 12.4 8.8 4.5 7.2 9.1 8.8 11.0 3.8 4.3 9.8 14.1 31.2 34.3 7.1 3.7 16.4 1.6 6.5 2.7 11.9 7.7 5.8 7.2 3.4 7.1 6.7 7.1 2.1 11.8 7.7 3.9 29.0 11.9 2.9 4.4 10.0 7.8 9.4 11.0 13.1 4.5 3.9 0.8 0.0 0.1 0.3 0.1 0.1 0.6 1.8 7.6 8.0 7.2 0.1 12.1 0.6 1.0 2.3 0.6 0.9 0.0 0.3 0.4 9.9 0.1 13.0 0.4 0.3 1.0 0.2 0.3 0.4 0.0 0.1 0.0 1.2 1.9 0.3 0.4 2.3 0.0 0.2 6.6 0.3 0.4 0.1 0.1 11.1 0.2 0.4 0.1 18.3 0.2 0.5 0.3 0.7 0.3 0.6 0.5 1.4 0.4 0.3 1.6 0.2 0.2 16.0 0.3 0.3 0.3 0.1 2.3 0.6 4.1 0.4 7.1 14.1 6.1 2.5 7.6 7.9 2.2 3.3 5.6 5.2 5.6 13.8 14.5 0.9 9.0 5.5 4.0 3.9 4.4 4.8 3.8 4.3 7.1 3.7 7.7 3.9 4.4 3.9 84.4 32.1 39.3 0.0 28.3 4.6 9.1 20.7 1.8 2.8 3.5 2.4 3.6 8.6 25.3 5.5 8.4 0.9 29.0 5.1 0.0 2.2 1.9 4.8 8.4 81.2 0.0 11.2 0.5 3.3 1.6 22.2 9.2 7.4 21.5 17.9 92.4 6.5 8.3 0.0 2.5 4.3 4.1 29.2 10.9 1.2 3.7 33.7 5.4 15.9 33.8 15.5 36.0 1.0 0.6 36.3 1.9 1.9 7.2 24.4 4.4 1.5 43.3 12.2 0.0 5.3 11.3 2.4 3.4 2.9 3.0 1.5 34.2 122.6 2.4 13.6 GCA GCL ENSG00000115271 Grancalcin P28676 2 162318840-162371595 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "bone marrow: 325.7" "Cell type enhanced" "Detected in all" "Early spermatids: 185.0;Kupffer cells: 183.3;Macrophages: 153.5;monocytes: 228.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 327.4;neutrophil: 864.2" "Lineage enriched" "Detected in all" 7 "granulocytes: 864.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035033, HPA035034" Enhanced Supported "Plasma membrane,Cytosol" NA NA 1300000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Cytosol "Plasma membrane" "HPA035033: AB_10669854, HPA035034: AB_10669900" "unprognostic (9.62e-2)" "unprognostic (9.76e-2)" "unprognostic (3.33e-1)" "unprognostic (3.82e-2)" "unprognostic (2.60e-1)" "unprognostic (1.06e-1)" "unprognostic (2.33e-3)" "unprognostic (1.36e-1)" "unprognostic (8.87e-2)" "unprognostic (2.49e-2)" "unprognostic (1.20e-1)" "unprognostic (9.78e-2)" "unprognostic (6.56e-2)" "unprognostic (5.80e-2)" "unprognostic (3.07e-1)" "unprognostic (3.06e-2)" "unprognostic (1.32e-2)" 30.5 13.5 16.4 62.6 23.0 325.7 17.6 20.2 28.8 12.2 11.4 18.0 19.3 9.8 24.6 10.9 16.2 23.0 9.7 15.9 17.7 18.3 15.0 26.5 33.0 25.5 20.7 8.5 16.6 10.4 8.2 25.2 23.6 12.2 19.6 10.6 12.3 9.7 2.7 7.0 18.7 18.8 21.6 70.1 25.1 24.1 19.5 18.4 17.0 14.9 25.4 26.1 5.7 37.3 2.6 4.2 10.7 0.0 2.5 2.2 0.4 4.0 11.1 6.2 11.1 8.7 30.6 3.7 27.0 0.3 14.2 1.6 4.1 12.7 7.7 17.1 16.8 33.5 2.9 17.7 3.0 41.6 9.1 2.8 4.3 5.7 1.2 15.8 0.9 25.9 0.6 12.1 0.5 33.0 0.9 24.2 6.5 22.5 16.4 14.2 2.7 18.5 32.7 18.6 6.9 12.0 5.1 23.3 19.7 12.5 15.8 17.7 0.8 1.6 11.2 17.8 6.2 11.5 23.2 0.6 9.2 15.8 7.7 38.8 132.4 327.4 2.7 78.4 3.5 21.6 4.8 4.8 63.2 21.1 8.1 5.0 864.2 2.5 63.3 17.2 10.2 71.4 16.4 23.0 20.2 28.8 15.9 17.7 25.5 20.7 23.6 21.6 19.5 37.3 28.8 16.0 36.5 10.1 54.5 15.4 28.2 19.6 12.5 10.2 32.6 16.4 4.1 50.1 21.2 33.1 2.1 55.5 17.3 14.4 76.3 49.5 185.0 21.1 9.1 26.4 39.4 36.1 25.9 60.5 20.8 14.4 43.8 24.9 44.9 13.6 48.9 15.0 107.9 11.8 15.4 29.9 32.6 183.3 60.5 32.8 10.8 153.5 16.0 17.8 228.5 21.1 10.3 1.0 98.0 36.5 25.7 6.4 23.4 24.3 18.4 69.7 24.7 4.4 6.6 12.2 18.3 52.6 13.5 15.1 18.2 46.9 16.3 16.7 28.9 21.0 GFI1B ZNF163B ENSG00000165702 "Growth factor independent 1B transcriptional repressor" Q5VTD9 9 132944000-132991687 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Developmental protein, DNA-binding, Repressor" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 18 "bone marrow: 39.0" "Cell type enriched" "Detected in some" 4 "Erythroid cells: 99.1" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 20 "basophil: 195.6;eosinophil: 395.8" "Lineage enriched" "Detected in many" 26 "granulocytes: 395.8" "Group enriched" "Detected in some" 5 "HEL: 168.9;HMC-1: 104.6;K-562: 53.0" "Not detected" "Not detected" "Not detected" "Not detected" "CAB004420, HPA006291" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004420: AB_2110132, HPA006291: " "unprognostic (1.79e-2)" "unprognostic (2.90e-4)" "unprognostic (6.54e-2)" "unprognostic (1.76e-1)" "unprognostic (2.33e-1)" "unprognostic (1.54e-2)" "unprognostic (2.53e-3)" "unprognostic (1.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.54e-1)" "unprognostic (4.61e-2)" "unprognostic (3.71e-2)" "unprognostic (2.17e-1)" "unprognostic (2.53e-1)" "unprognostic (1.53e-2)" "unprognostic (1.41e-1)" 0.0 0.0 0.0 0.3 0.1 39.0 0.0 0.2 0.2 0.0 0.2 0.5 0.9 0.0 0.1 0.1 0.0 0.3 0.2 0.1 0.0 0.0 0.2 1.1 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.3 0.0 0.1 0.1 0.4 0.5 1.0 0.1 0.1 1.8 0.3 2.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 0.4 0.3 0.1 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.0 1.9 0.3 23.8 0.0 0.0 0.0 1.5 0.0 0.6 0.0 0.0 0.0 168.9 0.2 0.1 0.0 0.1 104.6 0.0 1.4 0.0 0.2 0.0 0.0 0.0 53.0 0.2 0.0 0.0 0.1 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.5 0.0 1.5 0.0 0.0 0.0 195.6 0.3 395.8 0.1 1.9 0.1 0.1 0.1 0.0 1.9 0.2 0.5 0.1 3.9 0.5 15.1 1.0 0.0 12.5 0.0 0.1 0.2 0.2 0.1 0.0 0.4 0.1 0.1 0.1 0.1 0.4 0.2 0.0 0.6 0.0 0.4 0.0 0.4 0.0 0.0 0.0 0.2 0.0 1.3 0.0 1.8 0.0 0.0 0.1 0.1 0.8 0.0 0.1 3.8 0.0 0.3 0.4 1.2 99.1 0.4 0.0 0.2 0.3 0.0 0.1 14.5 0.4 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.3 0.0 12.9 0.0 15.8 0.0 0.0 0.6 0.0 0.0 0.5 0.2 0.0 24.2 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.4 0.4 0.0 0.0 0.3 0.2 1.0 0.6 0.1 GFRA3 GFRa-3 ENSG00000146013 "GDNF family receptor alpha 3" O60609 5 138252380-138274621 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 13.0" "Cell type enhanced" "Detected in some" "Early spermatids: 8.7;Enteroendocrine cells: 53.1;granulocytes: 26.7;Late spermatids: 20.9;Spermatogonia: 8.4" "Cancer enhanced" "Detected in many" "endometrial cancer: 11.9" "Region enriched" "Detected in single" 8 "cerebellum: 2.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "SH-SY5Y: 32.0" "Not detected" "Not detected" HPA020731 Approved Uncertain "Plasma membrane,Cytosol" NA NA 150000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane" Cytosol "HPA020731: AB_1849635" "unprognostic (1.22e-1)" "unprognostic (6.35e-2)" "unprognostic (1.64e-1)" "unprognostic (1.28e-1)" "unprognostic (2.57e-1)" "unprognostic (4.47e-2)" "unprognostic (1.47e-3)" "unprognostic (2.77e-3)" "unprognostic (1.27e-1)" "unprognostic (7.65e-3)" "unprognostic (1.44e-1)" "unprognostic (1.33e-2)" "unprognostic (1.90e-5)" "unprognostic (2.19e-2)" "unprognostic (3.35e-1)" "unprognostic (1.79e-1)" "unprognostic (6.23e-2)" 1.8 1.6 0.0 2.1 0.2 0.0 1.6 2.5 0.3 7.4 0.0 13.0 2.7 0.5 2.5 2.3 1.2 1.9 5.7 0.1 0.2 0.5 0.5 2.0 0.1 0.1 0.1 1.3 3.7 0.0 2.0 0.0 0.2 4.1 3.8 0.0 3.2 5.9 0.2 3.1 3.3 2.0 0.1 0.0 6.3 4.2 0.1 0.5 0.8 0.4 0.1 5.1 7.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.2 0.1 0.1 0.0 0.0 2.0 1.2 0.5 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.1 32.0 0.5 0.0 0.3 0.2 0.1 1.1 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 2.5 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 0.0 1.8 0.0 0.7 0.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 8.7 0.0 0.0 0.0 53.1 0.0 0.2 0.2 0.2 0.5 0.0 0.0 26.7 0.3 0.0 0.0 0.1 0.0 0.1 0.2 6.1 0.0 0.2 20.9 0.0 0.2 1.8 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 3.8 8.4 0.1 0.0 0.3 0.0 0.1 0.0 0.1 GINM1 "C6orf72, dJ12G14.2" ENSG00000055211 "Glycoprotein integral membrane 1" Q9NU53 6 149566294-149591748 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 369.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017210, HPA041679" Approved Approved "Nucleoli fibrillar center,Plasma membrane" NA NA 35000 "Cluster 19: B-cells - Humoral immune response" "Cluster 1: Thyroid gland - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center, Plasma membrane" "HPA017210: AB_1845743, HPA041679: AB_2677611" "unprognostic (6.09e-3)" "unprognostic (2.19e-2)" "unprognostic (2.38e-1)" "unprognostic (2.48e-1)" "unprognostic (7.24e-2)" "unprognostic (1.32e-3)" "unprognostic (3.18e-2)" "unprognostic (1.27e-1)" "unprognostic (2.31e-1)" "unprognostic (8.23e-2)" "unprognostic (1.05e-1)" "unprognostic (2.10e-2)" "unprognostic (2.09e-2)" "unprognostic (2.88e-2)" "unprognostic (2.64e-2)" "unprognostic (4.87e-2)" "unprognostic (4.79e-3)" 56.0 44.0 25.7 24.0 31.4 41.2 45.0 33.9 36.1 47.8 38.5 43.0 25.9 46.4 44.6 32.2 39.2 38.2 58.6 25.0 28.9 92.7 45.7 36.0 26.1 30.6 29.0 50.5 36.8 55.3 24.7 62.6 30.6 40.3 34.8 21.9 32.2 47.4 47.1 36.4 28.1 50.5 29.3 35.1 34.1 48.0 26.9 21.7 73.9 42.3 24.7 42.2 34.0 38.9 27.2 19.5 30.5 41.4 162.6 96.1 48.3 89.0 107.5 68.1 85.1 25.4 35.7 19.4 46.9 87.6 62.9 53.8 20.1 46.0 89.0 33.6 39.6 18.9 17.5 30.5 62.0 37.2 17.2 107.8 39.1 58.0 39.6 74.7 74.7 27.0 24.6 31.8 65.1 35.3 22.9 27.9 10.1 40.2 20.1 25.2 54.0 15.1 97.7 23.9 19.2 18.1 90.1 53.2 18.9 33.5 32.9 38.4 51.3 35.9 37.0 92.9 60.9 30.6 38.6 24.5 67.4 33.1 34.3 21.0 18.5 25.1 8.8 17.8 10.5 22.8 10.2 9.7 13.9 17.0 9.8 8.0 32.1 11.4 23.4 16.9 10.7 10.6 25.7 31.4 33.9 36.1 25.0 28.9 30.6 29.0 30.6 29.3 26.9 38.9 120.5 80.1 53.7 10.1 44.6 46.8 58.6 75.1 46.7 21.3 50.1 50.3 54.1 38.6 53.4 66.2 29.2 81.1 31.4 64.5 39.2 92.7 191.0 42.2 77.3 78.9 26.8 32.2 11.9 80.7 77.1 103.4 18.3 60.7 29.1 48.2 104.6 41.9 45.6 16.8 13.9 23.1 46.8 56.0 47.7 369.6 129.5 46.6 42.7 5.6 75.7 86.5 18.6 17.1 25.0 67.8 33.5 112.8 45.3 65.0 49.8 132.1 33.8 22.6 98.6 85.9 71.1 166.5 82.8 48.7 47.0 122.7 32.0 65.7 22.4 64.0 GJB7 "bA136M9.1, CX25" ENSG00000164411 "Gap junction protein beta 7" Q6PEY0 6 87282980-87329278 "Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 5 "fallopian tube: 7.0;pituitary gland: 5.5;placenta: 2.6" "Cell type enhanced" "Detected in some" "Cytotrophoblasts: 10.4;Endometrial ciliated cells: 12.8;Ionocytes: 22.4;Respiratory ciliated cells: 18.4;Syncytiotrophoblasts: 7.3" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 4.5;HDLM-2: 7.6;MCF7: 4.1;OE19: 4.8;RT4: 3.6;SuSa: 2.4" "Not detected" "Not detected" HPA014392 Approved "Plasma membrane,Cytosol" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA014392: " "unprognostic (8.30e-2)" "unprognostic (2.45e-1)" "unprognostic (3.06e-1)" "unprognostic (4.20e-1)" "unprognostic (2.84e-1)" "unprognostic (4.07e-3)" "unprognostic (2.61e-1)" "unprognostic (5.13e-3)" "unprognostic (6.69e-3)" "unprognostic (1.59e-1)" "unprognostic (3.82e-2)" "unprognostic (4.15e-2)" "unprognostic (3.24e-1)" "unprognostic (5.64e-2)" "unprognostic (2.09e-2)" "unprognostic (3.10e-2)" 0.0 0.0 0.2 0.0 0.1 0.3 0.0 1.0 0.6 0.2 0.0 0.0 0.0 0.1 0.0 0.0 7.0 0.0 0.1 0.1 0.1 0.0 0.0 0.7 0.0 0.4 0.1 0.0 0.0 0.1 5.5 2.6 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.1 0.0 0.0 0.0 0.1 0.2 0.0 0.2 1.5 0.0 0.1 0.1 0.0 0.0 4.5 0.0 0.0 0.0 0.0 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.6 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 0.0 4.1 0.0 0.1 1.2 4.8 0.0 0.1 0.0 0.0 0.0 3.6 0.1 0.0 0.8 0.0 0.0 2.4 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 1.0 0.6 0.1 0.1 0.4 0.1 0.5 0.0 0.1 0.2 0.2 0.0 0.0 0.7 0.1 0.0 0.0 1.3 0.0 2.5 0.6 0.3 0.2 0.0 0.5 0.0 0.0 10.4 0.5 0.1 0.0 0.2 1.1 12.8 0.8 0.3 0.0 0.0 0.7 0.2 4.4 0.6 0.0 3.0 0.0 0.1 0.4 0.0 0.5 0.0 1.1 0.0 22.4 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.1 0.4 0.0 0.0 0.0 0.0 18.4 0.6 0.0 1.7 0.3 0.3 0.3 0.0 0.0 7.3 0.5 0.2 0.3 0.2 GJC2 "CX46.6, CX47, GJA12, SPG44" ENSG00000198835 "Gap junction protein gamma 2" Q5T442 1 228149930-228159826 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant, Hereditary spastic paraplegia, Leukodystrophy, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 51.3" "Group enriched" "Detected in many" 4 "Cone photoreceptor cells: 12.5;Oligodendrocytes: 26.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.4;SCLC-21H: 2.9;TIME: 2.7" "Region enhanced" "Detected in all" "white matter: 105.5" "Low region specificity" "Detected in all" HPA069619 Supported "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 38: EFO-21 - Unknown function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA069619: " "unprognostic (2.67e-1)" "unprognostic (1.81e-2)" "unprognostic (6.42e-2)" "unprognostic (8.19e-3)" "unprognostic (4.24e-1)" "unprognostic (1.57e-1)" "unprognostic (6.94e-2)" "unprognostic (2.56e-1)" "unprognostic (4.99e-2)" "unprognostic (7.09e-2)" "unprognostic (7.88e-3)" "unprognostic (9.67e-2)" "unprognostic (6.09e-3)" "unprognostic (2.53e-2)" "unprognostic (7.36e-2)" "unprognostic (1.54e-1)" "unprognostic (2.02e-1)" 2.9 0.9 13.6 0.6 31.2 0.2 1.7 39.0 20.2 4.2 5.2 5.8 0.2 4.7 0.9 1.4 5.4 0.7 1.7 13.9 19.5 1.3 0.5 2.9 0.6 43.9 31.6 3.8 0.5 0.7 1.4 0.5 38.1 3.0 0.3 0.5 0.8 1.7 0.8 1.7 1.7 1.8 28.1 1.4 2.4 1.2 27.6 0.4 2.0 0.8 0.3 4.2 3.5 51.3 0.2 0.2 0.1 0.3 0.8 0.4 1.0 0.8 0.2 0.3 0.4 0.5 0.7 0.1 5.4 1.5 0.4 0.5 0.2 0.2 0.1 0.2 0.9 0.2 1.4 1.2 1.4 0.0 0.0 0.2 0.1 0.5 0.3 0.7 0.1 1.0 0.6 0.1 0.2 0.3 1.1 0.3 0.3 0.0 1.1 0.2 0.1 0.0 0.4 0.0 2.9 1.7 0.2 0.0 0.2 0.1 0.1 0.2 2.7 0.7 2.1 2.5 0.9 0.1 0.4 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 13.6 31.2 39.0 20.2 13.9 19.5 43.9 31.6 38.1 28.1 27.6 51.3 2.8 0.0 0.6 0.7 0.2 3.4 1.3 0.6 1.8 2.6 1.3 0.6 1.8 0.0 0.0 0.0 12.5 0.0 0.4 0.2 0.0 0.1 0.2 1.0 1.1 4.3 0.0 0.0 0.8 0.5 0.0 2.2 0.0 1.6 0.0 0.3 3.6 0.0 0.1 3.3 1.1 0.3 0.0 0.6 3.8 0.0 2.5 1.3 1.8 0.0 0.0 0.3 0.0 0.0 26.9 1.1 0.0 4.1 0.0 0.6 0.0 0.0 0.0 1.0 0.0 0.6 1.8 0.0 0.0 0.5 1.7 0.0 0.8 0.6 0.3 1.0 GLDN "CLOM, COLM, colmedin, CRG-L2, UNC-122" ENSG00000186417 Gliomedin Q6ZMI3 15 51341655-51408005 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 84.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 510.8" "Cancer enhanced" "Detected in many" "glioma: 4.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HHSteC: 2.7;MCF7: 1.3;SuSa: 1.8;U-266/70: 3.3;U-266/84: 2.9" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA050873, HPA059441" Uncertain Supported "Vesicles,Plasma membrane" "Secreted to extracellular matrix" NA NA 410000 "Cluster 70: Brain - Nervous system development" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA050873: , HPA059441: AB_2684018" "unprognostic (5.04e-2)" "unprognostic (2.57e-2)" "unprognostic (5.15e-5)" "unprognostic (3.21e-3)" "unprognostic (2.82e-2)" "unprognostic (2.33e-1)" "unprognostic (2.07e-4)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (3.30e-2)" "unprognostic (3.15e-1)" "unprognostic (2.14e-2)" "unprognostic (9.89e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-1)" "unprognostic (3.80e-3)" "unprognostic (1.37e-1)" 18.5 2.3 18.1 1.6 51.1 0.7 9.7 35.0 28.6 1.8 0.0 3.5 0.2 0.5 0.5 0.5 1.2 3.4 5.0 15.5 31.2 0.4 0.1 8.7 0.2 47.6 48.9 0.5 0.5 0.4 0.6 3.9 56.4 2.4 6.4 1.3 1.4 0.7 1.0 5.0 0.6 0.6 26.0 2.9 2.1 0.2 41.7 0.1 0.8 0.9 0.2 1.5 1.5 84.8 0.1 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 0.1 0.0 0.1 0.5 0.8 0.0 0.0 0.0 0.0 1.1 0.2 0.0 0.0 1.0 0.0 1.8 0.0 0.5 0.0 0.0 0.0 0.1 0.0 3.3 2.9 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 18.1 51.1 35.0 28.6 15.5 31.2 47.6 48.9 56.4 26.0 41.7 84.8 40.1 0.0 2.6 2.0 0.0 6.2 0.0 0.3 0.0 9.2 0.2 0.3 8.4 0.0 0.1 0.0 0.0 5.2 0.0 47.0 0.0 0.0 0.0 0.0 0.1 3.7 1.2 0.0 7.4 0.0 0.6 7.9 4.6 0.2 0.0 4.5 0.0 0.2 4.9 0.0 17.2 1.7 0.0 14.9 9.5 0.0 0.3 16.1 3.6 42.2 0.0 0.3 0.0 2.0 510.8 0.1 28.6 0.0 0.0 0.1 0.0 0.1 0.9 0.8 0.0 4.7 9.8 0.1 0.1 0.0 4.0 100.4 0.6 0.4 5.1 1.6 GLRX "GRX, GRX1" ENSG00000173221 Glutaredoxin P35754 5 95751319-95822726 "Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Electron transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 777.4" "Cell type enhanced" "Detected in many" "Distal tubular cells: 723.9;Extravillous trophoblasts: 751.2;Proximal enterocytes: 968.3;Proximal tubular cells: 1165.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "BJ hTERT+: 569.0;RPTEC TERT1: 462.1;U-87 MG: 441.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB008634, HPA046431, CAB069419" Approved Supported "Plasma membrane,Cytosol" NA NA 6300000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB008634: AB_1616672, CAB069419: AB_1616670, HPA046431: AB_2679663" "unprognostic (1.69e-1)" "unprognostic (1.32e-1)" "unprognostic (1.94e-2)" "unprognostic (4.81e-2)" "unprognostic (2.01e-2)" "unprognostic (2.22e-2)" "unprognostic (8.62e-3)" "unprognostic (9.31e-3)" "unprognostic (1.99e-2)" "unprognostic (1.65e-2)" "unprognostic (2.34e-1)" "unprognostic (1.82e-1)" "unprognostic (8.11e-2)" "unprognostic (2.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.61e-1)" "unprognostic (2.61e-1)" 82.1 101.4 32.5 80.0 34.9 173.7 37.2 46.3 52.4 28.2 29.0 57.2 194.7 12.7 10.1 13.6 17.2 50.8 102.7 47.3 37.1 247.4 143.6 71.9 61.5 52.0 42.1 10.9 10.9 82.4 23.7 102.0 39.8 28.5 47.4 6.9 59.2 25.6 777.4 38.3 170.3 25.7 34.3 64.9 40.2 4.9 43.6 75.6 18.9 55.9 80.4 53.1 20.9 37.9 22.2 97.1 8.4 18.0 211.3 310.4 1.6 326.5 569.0 35.9 62.9 31.2 10.2 86.2 45.7 99.0 83.0 9.7 12.9 156.4 100.5 75.7 24.1 62.8 63.5 248.1 386.6 67.2 182.8 184.4 23.2 219.7 21.3 81.1 75.3 179.3 8.2 51.3 262.3 7.9 121.4 133.0 22.2 3.3 111.6 186.1 66.8 107.9 462.1 16.8 23.6 12.5 85.3 47.8 39.4 22.0 13.0 66.0 78.0 91.9 101.9 74.6 14.4 37.1 202.0 70.4 441.3 170.6 19.7 48.9 727.2 901.6 222.9 483.8 313.6 142.9 205.0 166.7 459.8 107.8 201.4 186.1 783.8 113.4 411.2 166.6 457.7 781.7 32.5 34.9 46.3 52.4 47.3 37.1 52.0 42.1 39.8 34.3 43.6 37.9 77.5 22.4 28.4 3.6 74.1 17.2 62.9 330.5 8.6 2.2 57.9 31.5 154.9 65.8 183.6 93.8 0.0 47.4 130.0 173.8 723.9 60.4 0.3 83.4 49.0 47.1 31.7 63.1 8.7 96.0 751.2 63.1 35.7 118.0 31.6 3.5 46.4 206.9 271.5 0.0 8.0 89.9 65.1 304.9 276.1 2.3 19.0 232.3 69.4 12.2 340.0 7.8 302.8 2.0 2.4 113.5 291.3 13.9 200.2 89.5 968.3 1165.9 124.1 3.9 19.7 22.1 67.0 0.6 1.6 4.1 20.6 285.3 97.7 11.7 85.4 214.6 GNB1 ENSG00000078369 "G protein subunit beta 1" P62873 1 1785285-1891117 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins, Transporters" Transducer "Cancer-related genes, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 11 "retina: 2629.0" "Cell type enriched" "Detected in all" 5 "Rod photoreceptor cells: 1373.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA040736 Supported Approved "Golgi apparatus,Plasma membrane" NA NA 1900000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (9.49e-2)" "unprognostic (4.91e-3)" "unprognostic (1.24e-1)" "unprognostic (1.56e-1)" "unprognostic (3.34e-1)" "unprognostic (9.07e-3)" "prognostic unfavorable (3.61e-6)" "unprognostic (1.99e-2)" "unprognostic (3.60e-1)" "unprognostic (7.27e-2)" "unprognostic (8.47e-3)" "unprognostic (1.95e-1)" "unprognostic (9.76e-2)" "unprognostic (1.08e-1)" "unprognostic (4.62e-2)" "unprognostic (1.14e-1)" "unprognostic (7.90e-2)" 178.1 123.8 167.9 179.9 212.3 147.6 119.7 147.8 234.4 124.3 87.1 165.7 173.7 127.1 90.8 126.7 114.4 110.9 119.6 228.3 172.0 125.1 103.3 146.7 160.0 159.5 153.2 130.2 105.9 148.2 106.8 141.1 169.5 118.3 123.1 2629.0 120.6 118.9 66.8 111.8 208.2 156.1 131.6 142.6 129.7 99.0 168.9 167.3 113.6 97.1 145.6 152.6 102.7 203.9 373.2 344.2 400.2 280.4 222.4 242.4 154.4 515.4 339.9 456.2 355.2 282.8 361.8 385.5 369.3 522.5 258.6 192.0 405.5 373.5 411.4 595.9 199.2 375.0 308.2 325.6 279.1 227.7 394.4 216.4 256.6 437.2 402.9 306.1 376.8 298.8 236.8 337.8 440.0 230.3 501.9 177.4 230.8 190.0 275.0 482.9 308.7 306.4 310.8 227.5 489.9 556.5 477.1 306.6 420.5 272.8 214.8 305.9 579.4 399.3 267.5 314.8 379.1 227.1 432.8 888.7 341.4 470.1 230.5 11.4 13.3 21.9 9.9 16.4 9.1 9.0 9.9 11.2 13.3 9.6 6.7 7.2 22.1 12.8 17.5 22.7 12.5 8.2 167.9 212.3 147.8 234.4 228.3 172.0 159.5 153.2 169.5 131.6 168.9 203.9 172.0 70.5 42.6 57.5 67.9 86.3 51.6 47.4 33.0 149.8 65.3 57.8 60.6 52.9 42.4 75.4 175.2 44.2 124.4 140.9 46.9 88.0 29.1 93.3 112.9 131.6 122.9 40.3 102.4 100.5 99.4 77.8 52.0 121.6 53.8 101.9 95.3 60.3 100.8 180.0 101.9 95.5 40.7 152.7 114.6 33.8 76.1 128.0 53.4 115.2 119.5 250.3 73.2 70.9 110.1 175.4 91.0 88.0 75.3 100.5 167.6 67.4 41.1 1373.7 78.9 71.0 105.9 68.8 67.1 51.6 101.7 36.4 74.5 83.7 83.0 94.1 GNB3 ENSG00000111664 "G protein subunit beta 3" P16520 12 6839954-6847393 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" Transducer "Congenital stationary night blindness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "retina: 426.5" "Group enriched" "Detected in many" 7 "Bipolar cells: 471.3;Cone photoreceptor cells: 932.0;Rod photoreceptor cells: 462.8" "Cancer enhanced" "Detected in some" "testis cancer: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Daudi: 14.1;NTERA-2: 17.0;U-698: 40.9" "Low region specificity" "Detected in some" "Region enhanced" "Detected in some" "cerebellum: 5.1" HPA040736 Uncertain Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 79: Retina - Phototransduction" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" "Golgi apparatus" "HPA040736: AB_2677106" "unprognostic (3.86e-2)" "unprognostic (1.58e-1)" "unprognostic (4.96e-2)" "unprognostic (8.75e-2)" "unprognostic (2.53e-2)" "unprognostic (5.74e-3)" "unprognostic (5.98e-2)" "unprognostic (4.43e-3)" "unprognostic (1.19e-1)" "unprognostic (1.98e-1)" "unprognostic (2.25e-5)" "unprognostic (3.21e-2)" "unprognostic (4.77e-11)" "unprognostic (2.43e-1)" "unprognostic (6.48e-2)" "unprognostic (1.36e-1)" "unprognostic (1.07e-2)" 0.9 1.4 6.3 1.6 6.0 1.0 0.6 6.7 9.5 2.3 6.7 1.4 1.7 2.2 0.7 0.4 1.6 1.1 4.4 5.9 6.6 2.0 0.2 0.7 1.6 5.7 5.3 2.8 0.7 1.5 36.2 0.4 5.6 2.1 0.6 426.5 2.1 1.4 1.3 0.7 1.5 3.2 5.2 0.9 1.0 0.6 5.7 0.3 1.6 0.3 1.6 1.6 1.1 6.4 0.4 1.2 9.4 3.1 1.3 2.0 0.9 4.8 0.8 2.5 2.1 1.9 0.5 14.1 0.1 5.1 0.1 0.5 9.2 0.3 2.3 1.2 2.1 3.4 6.8 1.5 0.9 1.1 2.3 2.4 0.5 2.4 2.7 9.6 2.5 1.8 1.5 1.3 1.2 0.7 0.7 0.8 17.0 0.1 0.5 0.7 2.8 0.9 0.5 0.4 1.1 2.2 0.4 0.1 1.0 2.5 0.1 0.6 4.0 3.2 3.8 4.8 6.7 1.4 1.0 40.9 1.3 0.7 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 6.0 6.7 9.5 5.9 6.6 5.7 5.3 5.6 5.2 5.7 6.4 0.3 0.0 0.0 5.2 1.3 0.4 0.4 0.2 1.2 471.3 0.8 1.3 6.1 0.0 0.1 0.0 932.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 2.0 3.3 0.0 1.3 12.3 0.0 0.0 2.3 2.0 0.1 0.0 0.1 1.1 0.0 0.1 74.0 12.4 0.0 4.1 0.3 0.4 0.0 3.7 0.1 1.8 3.7 0.1 86.7 0.0 6.0 1.2 0.1 0.0 3.4 3.2 0.8 0.0 0.1 0.6 462.8 0.0 0.3 1.4 0.1 0.5 0.0 0.0 0.0 0.4 0.2 0.1 0.2 GNG2 ENSG00000186469 "G protein subunit gamma 2" P59768 14 51826195-51979342 "Predicted intracellular proteins, RAS pathway related proteins" Transducer "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 113.4" "Cell type enhanced" "Detected in many" "dendritic cells: 251.8;Early spermatids: 714.4;Late spermatids: 1146.4;NK-cells: 246.1" "Cancer enhanced" "Detected in all" "glioma: 15.4" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "AF22: 77.2;fHDF/TERT166: 140.2;MOLT-4: 112.5;SH-SY5Y: 89.2;WM-115: 249.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003534, CAB018380" Uncertain Supported Approved "Vesicles,Plasma membrane" NA NA 170000 "Cluster 46: Basophils - DNA binding" "Cluster 65: Brain - Ion transport" "Cluster 17: WM-115 - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Vesicles "CAB018380: AB_631547, HPA003534: AB_1079004" "unprognostic (6.11e-2)" "unprognostic (5.78e-3)" "unprognostic (2.06e-3)" "unprognostic (6.55e-2)" "unprognostic (1.33e-1)" "unprognostic (4.01e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (5.72e-2)" "unprognostic (1.24e-1)" "prognostic favorable (1.64e-4)" "unprognostic (8.47e-2)" "prognostic unfavorable (3.90e-6)" "unprognostic (9.82e-2)" "unprognostic (1.29e-1)" "unprognostic (1.08e-1)" "unprognostic (3.59e-2)" 51.3 22.0 38.5 41.1 44.8 64.0 21.0 0.8 55.4 11.9 10.9 24.1 15.2 12.2 5.1 14.1 5.8 17.3 13.5 54.1 75.2 7.5 12.7 19.0 47.7 10.6 20.5 14.4 7.3 3.5 14.9 19.5 27.2 10.6 19.6 15.0 8.1 9.0 5.6 7.8 21.2 19.8 13.6 61.7 15.9 113.4 46.4 62.0 5.7 13.1 45.4 22.2 5.3 22.2 0.0 3.1 77.2 48.6 11.6 15.0 1.2 12.9 15.9 6.1 4.9 6.4 0.2 0.2 1.8 140.2 8.9 0.3 10.4 0.0 4.2 36.4 1.2 0.0 0.7 0.0 6.0 7.4 0.3 25.1 0.0 6.2 0.5 32.2 0.0 67.9 0.0 6.5 39.7 0.0 112.5 12.0 41.1 0.0 9.5 39.4 6.1 2.0 6.4 0.0 11.5 89.2 0.3 0.1 34.5 2.7 0.0 0.3 0.0 18.7 3.1 0.3 9.9 0.2 0.0 5.5 15.5 39.2 249.0 379.4 64.0 177.1 162.8 111.9 110.5 38.1 88.9 134.2 65.8 36.2 55.5 98.5 185.2 25.2 177.3 28.0 143.2 158.6 38.5 44.8 0.8 55.4 54.1 75.2 10.6 20.5 27.2 13.6 46.4 22.2 11.6 6.4 7.2 3.3 101.3 11.5 0.4 0.0 2.2 18.7 1.5 1.9 1.0 1.5 0.0 3.7 2.1 0.6 251.8 0.8 1.9 0.2 714.4 0.5 2.7 11.7 175.8 20.4 66.2 0.0 0.6 23.9 11.7 0.8 32.3 0.2 11.0 0.9 51.1 0.0 59.6 2.4 0.0 94.1 60.0 1146.4 9.9 84.0 55.2 24.4 33.3 0.7 246.1 96.0 3.2 0.5 0.1 6.0 62.7 0.2 0.1 0.9 0.0 2.2 39.5 10.2 12.2 11.2 4.6 1.3 6.7 0.7 191.5 2.2 0.5 0.2 GPC1 glypican ENSG00000063660 "Glypican 1" P35052 2 240435663-240468076 "Disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "skin 1: 226.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 199.8;Syncytiotrophoblasts: 102.7;Urothelial cells: 110.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030571, HPA070449" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 9500000 "Cluster 31: Skin - Epidermis development" "Cluster 17: WM-115 - Nervous system development" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA030571: AB_10602322, HPA070449: " "unprognostic (1.22e-2)" "unprognostic (2.53e-2)" "prognostic unfavorable (5.78e-5)" "prognostic unfavorable (1.55e-4)" "unprognostic (1.95e-1)" "unprognostic (1.83e-3)" "prognostic unfavorable (2.44e-6)" "unprognostic (1.00e-2)" "unprognostic (2.15e-1)" "unprognostic (5.08e-3)" "unprognostic (2.28e-1)" "unprognostic (4.38e-1)" "unprognostic (1.91e-1)" "unprognostic (4.40e-2)" "unprognostic (2.92e-1)" "unprognostic (1.95e-2)" "unprognostic (2.12e-2)" 36.8 78.5 42.8 9.0 37.0 0.4 30.7 25.3 64.4 44.5 3.1 36.7 5.8 37.1 9.3 88.4 30.8 8.5 145.2 41.7 28.5 47.6 35.7 21.9 1.4 29.2 30.4 45.1 25.8 9.8 55.7 29.0 26.3 67.8 3.5 5.0 35.2 22.5 134.2 226.0 17.4 16.4 11.3 15.6 23.0 48.7 46.0 9.1 15.7 35.3 6.6 35.1 62.3 24.8 69.0 92.9 21.6 56.7 64.3 61.5 87.3 161.5 78.8 18.3 21.2 33.3 74.9 1.8 21.8 172.0 100.1 186.0 11.7 114.7 3.8 33.3 9.8 0.1 80.7 41.7 92.2 1.6 6.2 54.3 73.4 41.2 21.3 38.1 9.7 3.4 0.4 3.3 47.5 36.0 1.3 0.6 33.7 7.7 20.5 12.3 98.2 16.1 15.0 109.6 21.5 14.4 105.7 91.9 10.1 19.3 29.1 7.0 45.6 97.3 162.3 46.9 67.8 0.7 0.4 0.8 69.4 1.7 111.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 42.8 37.0 25.3 64.4 41.7 28.5 29.2 30.4 26.3 11.3 46.0 24.8 1.2 16.0 6.1 45.7 0.7 45.9 69.6 62.2 56.3 22.4 8.3 18.2 53.2 21.5 34.0 25.8 2.1 73.7 0.3 3.7 7.9 27.8 0.9 6.2 24.7 2.8 0.0 0.0 53.0 10.8 199.8 21.0 1.5 8.9 4.5 49.4 11.0 26.3 9.1 25.2 45.0 7.0 16.2 0.6 7.7 3.8 19.0 1.2 35.6 5.6 1.6 24.9 1.0 18.6 8.9 17.6 0.9 7.5 0.9 67.0 0.5 2.3 30.2 6.4 26.3 33.9 38.2 2.2 9.9 44.8 46.2 102.7 1.9 14.5 3.6 110.5 GPC4 K-glypican ENSG00000076716 "Glypican 4" O75487 X 133300103-133415489 "Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins" "Deafness, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 51.3;Alveolar cells type 2: 29.2;Astrocytes: 54.5;Extravillous trophoblasts: 36.2;Granulosa cells: 30.6;Proximal tubular cells: 30.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 209.7;HAP1: 121.8;NTERA-2: 110.3;RPTEC TERT1: 276.6;SuSa: 242.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030834, HPA030836" Approved Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 190000 "Cluster 13: Striated muscle - Muscle contraction" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Nucleoplasm "HPA030834: , HPA030836: AB_10601327" "unprognostic (9.60e-2)" "unprognostic (8.67e-2)" "unprognostic (2.29e-1)" "unprognostic (8.21e-2)" "unprognostic (8.51e-3)" "unprognostic (5.90e-3)" "unprognostic (5.68e-2)" "prognostic favorable (3.51e-4)" "unprognostic (2.54e-2)" "unprognostic (1.26e-1)" "unprognostic (5.87e-3)" "unprognostic (1.30e-1)" "prognostic favorable (1.25e-5)" "unprognostic (1.97e-1)" "unprognostic (2.89e-1)" "unprognostic (2.75e-1)" "unprognostic (2.72e-1)" 9.6 9.8 5.9 4.9 6.4 0.1 5.6 5.0 5.8 12.0 4.6 22.5 10.6 10.8 16.4 7.4 11.2 9.0 7.9 6.3 7.5 20.6 1.8 17.4 2.5 7.2 6.9 12.3 10.8 5.6 16.6 29.0 6.0 8.0 10.9 1.2 13.0 11.4 24.3 3.8 10.8 17.7 6.6 5.7 16.9 7.8 4.9 8.4 5.9 20.0 2.0 10.3 5.2 8.5 0.0 0.0 209.7 8.3 8.9 1.3 26.0 1.6 0.0 0.0 0.0 0.1 0.5 0.3 71.7 1.2 0.0 0.1 121.8 0.1 0.0 0.0 11.5 0.0 0.0 0.0 0.2 0.0 0.0 37.3 0.1 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.2 6.0 0.1 0.1 110.3 0.0 3.2 0.6 19.2 0.0 276.6 8.4 0.1 1.5 0.8 0.1 0.1 242.0 3.2 3.2 0.0 21.3 24.8 0.0 13.6 0.0 0.0 0.1 0.0 0.0 31.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 6.4 5.0 5.8 6.3 7.5 7.2 6.9 6.0 6.6 4.9 8.5 1.7 51.3 29.2 54.5 0.2 1.5 3.7 14.7 14.2 0.0 2.9 2.0 4.4 5.7 8.7 23.9 0.0 0.5 0.2 2.5 3.9 7.0 0.6 5.9 1.7 1.2 2.4 0.0 4.7 12.7 36.2 14.4 6.6 10.0 0.0 30.6 0.0 0.0 2.5 0.0 1.4 11.1 4.1 0.6 3.9 2.1 2.1 2.0 1.8 14.0 1.1 1.0 0.0 4.5 4.3 16.5 4.3 0.4 0.1 1.4 4.6 30.3 12.8 0.1 0.0 6.3 13.6 2.4 23.6 2.3 0.4 3.1 1.0 1.4 11.3 0.6 GPR173 SREB3 ENSG00000184194 "G protein-coupled receptor 173" Q9NS66 X 53048789-53080615 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 18.4" "Cell type enhanced" "Detected in some" "Astrocytes: 43.4;Excitatory neurons: 19.7;Inhibitory neurons: 14.1;Oligodendrocyte precursor cells: 49.3;Oligodendrocytes: 42.3" "Cancer enhanced" "Detected in many" "glioma: 8.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 3.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "HAP1: 9.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003905 Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "HPA003905: AB_1078922" "unprognostic (2.68e-1)" "unprognostic (2.33e-1)" "unprognostic (4.95e-3)" "prognostic unfavorable (2.88e-6)" "unprognostic (3.87e-2)" "unprognostic (8.58e-2)" "unprognostic (2.73e-1)" "unprognostic (1.47e-1)" "unprognostic (1.92e-1)" "unprognostic (1.70e-2)" "prognostic favorable (2.33e-5)" "unprognostic (1.03e-1)" "prognostic unfavorable (2.47e-4)" "unprognostic (1.08e-4)" "unprognostic (2.83e-1)" "unprognostic (3.92e-2)" "unprognostic (6.95e-2)" 2.2 2.7 12.6 1.4 11.7 1.0 2.0 14.5 12.5 6.6 4.6 4.2 0.6 5.5 2.1 1.0 6.4 1.4 4.0 12.3 14.2 2.9 0.4 2.6 1.0 10.9 13.6 12.0 0.8 1.1 18.4 2.1 13.3 4.0 1.1 7.0 1.3 2.3 2.4 1.7 2.1 1.9 9.3 3.3 1.9 1.5 14.5 1.5 1.8 1.0 0.4 3.2 3.6 12.0 0.0 0.0 7.8 0.8 4.1 2.4 0.3 1.4 2.7 2.0 2.3 0.8 0.1 0.2 1.9 2.6 5.9 0.8 9.5 0.0 1.7 0.9 1.3 0.6 9.3 0.3 6.0 0.5 0.2 5.8 0.0 3.0 4.1 6.6 3.2 0.2 0.0 5.4 2.9 4.6 0.2 0.1 6.2 0.4 3.5 0.2 2.6 0.7 0.4 0.4 5.8 7.9 0.0 0.8 0.0 4.7 1.2 0.2 5.7 3.4 5.0 2.6 1.1 0.2 0.7 0.8 2.5 0.0 1.8 3.3 0.1 0.2 0.4 0.1 0.2 0.2 0.2 0.1 0.0 0.4 0.2 0.2 0.6 0.8 0.2 0.3 0.1 0.0 12.6 11.7 14.5 12.5 12.3 14.2 10.9 13.6 13.3 9.3 14.5 12.0 0.5 0.0 0.0 43.4 0.2 0.3 0.4 0.6 0.0 6.6 0.1 0.3 0.8 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 5.2 1.1 3.5 0.0 19.7 0.0 0.0 1.5 0.0 0.3 0.0 7.1 1.8 0.1 0.2 6.7 14.1 0.4 0.0 0.3 0.7 0.0 3.1 0.2 1.8 11.2 0.0 3.2 0.0 49.3 42.3 0.1 0.0 4.5 0.0 0.3 0.0 0.1 0.1 3.1 0.0 2.0 2.5 0.1 0.2 0.0 0.0 0.1 0.1 2.8 0.1 0.2 GPR20 ENSG00000204882 "G protein-coupled receptor 20" Q99678 8 141356470-141367286 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 4 "Sertoli cells: 72.3" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 18 "intermediate monocyte: 2.6;non-classical monocyte: 4.3" "Lineage enriched" "Detected in single" 22 "monocytes: 4.3" "Cell line enriched" "Detected in single" 6 "EFO-21: 4.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071337 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 38: EFO-21 - Unknown function" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Cytosol "HPA071337: " "unprognostic (4.47e-2)" "unprognostic (2.64e-3)" "unprognostic (5.18e-2)" "unprognostic (2.00e-2)" "unprognostic (7.47e-2)" "unprognostic (2.28e-1)" "unprognostic (4.43e-2)" "unprognostic (5.01e-2)" "unprognostic (3.54e-1)" "unprognostic (2.13e-2)" "unprognostic (1.57e-1)" "unprognostic (1.13e-1)" "unprognostic (1.07e-2)" "unprognostic (7.41e-2)" "unprognostic (5.50e-2)" "unprognostic (6.23e-2)" "unprognostic (4.07e-1)" 0.8 0.2 0.0 0.2 0.0 0.0 0.6 0.0 0.4 2.0 0.0 1.4 0.4 1.9 0.7 0.6 1.5 0.7 1.1 0.0 0.0 0.6 0.2 1.5 0.0 0.0 0.0 1.2 0.2 0.1 0.2 1.2 0.1 0.9 0.3 0.0 0.2 0.8 0.3 0.4 2.1 1.8 0.0 0.2 1.7 0.1 0.0 0.0 0.5 0.4 0.0 0.7 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.0 0.0 0.1 0.1 0.4 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.3 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 1.9 0.0 0.2 1.8 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 72.3 0.3 16.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 GPR50 "H9, Mel1c" ENSG00000102195 "G protein-coupled receptor 50" Q13585 X 151176584-151181465 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "pituitary gland: 17.1" "Not detected" "Not detected" "Cancer enhanced" "Detected in some" "head and neck cancer: 1.4" "Region enhanced" "Detected in some" "hypothalamus: 3.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "HEK 293: 5.0;SuSa: 4.0" "Group enriched" "Detected in many" 4 "hypothalamus: 14.4;white matter: 5.0" "Region enriched" "Detected in single" 10 "hypothalamus: 4.8" "HPA049862, HPA054678" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Plasma membrane" Nucleoplasm "HPA049862: AB_2680920, HPA054678: AB_2682570" "unprognostic (8.84e-3)" "unprognostic (5.59e-2)" "unprognostic (1.15e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.1 0.6 0.1 0.0 0.0 0.0 17.1 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 3.4 0.6 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 GPRC5A "PEIG-1, RAI3, RAIG1, TIG1" ENSG00000013588 "G protein-coupled receptor class C group 5 member A" Q8NFJ5 12 12891559-12917937 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 201.9;urinary bladder: 130.8" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 939.1;Club cells: 357.8;Distal enterocytes: 477.9;Pancreatic endocrine cells: 600.7;Paneth cells: 359.8;Urothelial cells: 1252.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 355.6;A549: 285.7;CAPAN-2: 1347.4;HaCaT: 351.2;SiHa: 492.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA007928, HPA046526" Enhanced Enhanced "Vesicles,Plasma membrane" NA Yes "Cluster 41: Basophils - Cellular respiration" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA007928: AB_1849318, HPA046526: AB_2679685" "unprognostic (4.79e-2)" "unprognostic (8.35e-2)" "unprognostic (4.21e-2)" "unprognostic (1.64e-1)" "unprognostic (4.65e-3)" "unprognostic (1.73e-1)" "unprognostic (2.38e-2)" "unprognostic (1.89e-2)" "unprognostic (3.48e-1)" "unprognostic (8.69e-3)" "prognostic unfavorable (4.63e-6)" "unprognostic (3.81e-1)" "prognostic unfavorable (9.02e-5)" "unprognostic (9.30e-2)" "unprognostic (4.34e-1)" "unprognostic (1.62e-2)" "unprognostic (2.49e-1)" 31.5 3.7 1.2 11.5 0.9 1.8 9.6 1.0 1.4 35.4 3.4 56.4 18.7 8.9 0.4 23.0 9.8 24.9 18.9 1.8 0.8 9.0 1.8 201.9 0.2 2.7 4.5 21.4 2.7 0.9 2.5 13.5 1.0 10.2 48.4 1.6 23.5 1.3 0.7 5.8 20.9 5.1 0.5 0.4 33.6 1.5 2.1 0.3 55.5 0.6 4.4 130.8 30.6 1.8 355.6 285.7 0.1 1.3 3.4 1.5 18.4 105.2 39.5 66.2 49.4 49.1 1347.4 0.1 8.6 83.3 67.2 351.2 1.0 50.1 101.7 0.4 4.3 0.2 105.4 2.2 23.8 0.1 0.3 1.8 66.5 27.5 6.7 82.3 40.9 0.0 0.5 0.3 2.9 251.7 0.2 0.3 1.6 130.0 43.5 0.2 6.7 0.3 133.6 69.6 0.5 0.6 492.0 36.8 15.9 52.3 10.9 1.0 4.0 2.6 83.9 156.1 4.3 0.2 0.3 0.3 34.6 0.3 2.0 0.9 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.0 0.0 1.2 0.9 1.0 1.4 1.8 0.8 2.7 4.5 1.0 0.5 2.1 1.8 10.0 939.1 200.2 0.0 1.0 12.5 329.6 202.8 4.6 0.1 80.6 41.7 1.9 11.5 357.8 46.0 0.0 3.8 1.5 477.9 0.0 46.9 0.1 91.8 54.1 15.8 8.3 0.0 0.2 72.1 11.7 108.5 176.9 288.1 10.1 0.2 8.6 0.2 1.6 0.0 0.4 43.5 61.1 0.3 18.0 0.4 13.4 9.6 51.6 0.0 0.6 3.5 0.0 0.0 0.1 600.7 359.8 10.1 0.5 320.1 114.0 0.2 86.3 0.4 0.0 23.0 38.8 1.5 0.3 22.7 9.1 1.1 4.9 0.7 110.4 1252.7 GPRIN1 "GRIN1, KIAA1893" ENSG00000169258 "G protein regulated inducer of neurite outgrowth 1" Q7Z2K8 5 176595802-176610156 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 22.1;pituitary gland: 8.1;retina: 6.9" "Group enriched" "Detected in some" 4 "Bipolar cells: 12.8;Excitatory neurons: 7.5;Horizontal cells: 21.9;Inhibitory neurons: 8.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HDLM-2: 56.5;SCLC-21H: 59.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036478, HPA070892" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Vesicles "HPA036478: AB_2675145, HPA070892: AB_2686321" "unprognostic (1.70e-1)" "unprognostic (7.38e-2)" "unprognostic (4.41e-2)" "unprognostic (5.66e-2)" "unprognostic (6.54e-3)" "unprognostic (3.06e-1)" "unprognostic (4.76e-6)" "prognostic unfavorable (6.83e-6)" "unprognostic (1.11e-1)" "unprognostic (1.45e-1)" "unprognostic (2.59e-3)" "unprognostic (1.56e-3)" "prognostic unfavorable (2.79e-7)" "unprognostic (4.24e-3)" "unprognostic (5.60e-2)" "unprognostic (2.21e-1)" "unprognostic (3.32e-3)" 0.5 1.6 16.9 0.8 15.9 0.2 0.3 6.8 19.5 0.3 0.0 1.1 3.8 0.4 0.0 0.8 0.1 0.3 0.4 22.1 15.7 0.6 0.4 0.4 0.8 4.3 3.5 0.0 0.6 0.1 8.1 0.3 5.1 0.2 0.4 6.9 0.3 0.0 0.3 1.0 3.2 0.7 3.3 0.4 0.8 1.5 14.8 0.9 0.2 0.2 1.1 0.3 0.2 6.6 7.5 7.9 9.8 14.1 2.1 4.6 8.3 9.8 5.1 7.5 9.7 9.6 4.8 17.0 19.6 5.3 22.0 6.5 6.3 6.8 6.5 56.5 4.3 0.3 4.1 3.4 0.9 0.4 4.2 2.3 5.1 8.1 1.2 1.5 5.5 3.8 9.1 24.0 6.3 19.7 1.8 0.0 9.9 5.0 15.4 31.7 10.9 10.1 8.4 7.7 59.5 34.1 11.4 3.2 17.7 1.2 7.4 6.5 6.8 13.8 16.0 5.3 14.5 0.4 2.3 4.8 11.9 0.8 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 15.9 6.8 19.5 22.1 15.7 4.3 3.5 5.1 3.3 14.8 6.6 0.4 0.0 0.0 0.3 0.5 2.4 0.1 0.3 0.6 12.8 0.4 0.3 0.3 0.0 0.1 0.0 0.0 0.1 0.4 0.3 1.9 0.4 0.0 0.5 0.6 1.0 1.8 0.0 7.5 1.8 0.9 0.4 0.0 1.2 0.0 0.3 0.0 0.0 0.9 21.9 8.0 0.3 0.0 0.0 0.3 0.0 0.3 0.2 0.0 1.9 0.1 1.1 1.0 2.5 0.3 1.6 0.1 0.0 0.8 0.2 0.0 0.3 0.4 3.1 0.0 1.5 0.3 0.7 2.7 0.4 1.4 0.1 0.3 0.4 0.2 0.1 GRAMD1A "FLJ90346, KIAA1533" ENSG00000089351 "GRAM domain containing 1A" Q96CP6 19 34994784-35026471 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Autophagy, Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "monocytes: 146.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008852, HPA012570" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 50: Non-specific - Ribosome" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Cytosol "HPA008852: AB_1079203, HPA012570: AB_2112577" "unprognostic (3.09e-2)" "unprognostic (4.62e-2)" "unprognostic (8.65e-2)" "unprognostic (1.01e-1)" "unprognostic (1.05e-1)" "unprognostic (2.87e-1)" "unprognostic (3.42e-3)" "unprognostic (5.96e-2)" "unprognostic (4.54e-1)" "unprognostic (5.70e-2)" "unprognostic (1.07e-2)" "unprognostic (2.91e-1)" "prognostic unfavorable (7.95e-12)" "unprognostic (2.04e-1)" "unprognostic (4.40e-1)" "unprognostic (2.90e-2)" "unprognostic (4.36e-2)" 37.9 36.9 17.8 28.0 15.9 23.9 31.1 16.4 24.5 33.2 17.5 30.1 15.1 32.5 5.3 11.6 36.2 16.5 30.3 17.4 18.5 27.4 21.2 58.1 28.8 21.8 20.7 38.4 80.8 17.8 29.2 16.8 21.5 32.6 8.4 5.1 55.6 17.0 47.8 14.5 23.3 18.9 18.2 42.1 35.8 16.6 21.5 18.7 25.4 18.9 12.8 35.7 20.1 17.1 17.3 106.0 21.3 41.5 23.9 27.5 19.6 21.6 27.5 21.8 21.6 39.8 11.9 10.8 41.2 25.2 19.3 9.5 22.2 31.9 8.2 48.9 47.3 24.6 25.5 36.8 48.3 21.7 41.1 46.5 19.9 16.1 26.7 36.6 71.5 54.1 31.8 5.7 16.0 13.2 46.5 23.6 38.6 28.4 12.7 47.1 6.9 10.7 24.8 2.5 30.8 64.4 20.0 12.7 33.7 18.4 19.4 20.6 38.9 34.9 22.3 8.0 29.6 8.8 26.3 22.4 23.5 19.6 27.0 23.1 5.7 5.4 3.5 9.6 7.3 0.6 4.6 2.7 5.1 1.2 3.5 5.4 12.7 5.7 19.9 1.7 4.1 3.8 17.8 15.9 16.4 24.5 17.4 18.5 21.8 20.7 21.5 18.2 21.5 17.1 51.0 22.4 37.3 28.1 23.6 20.8 64.4 15.1 18.2 15.8 22.0 18.7 12.3 0.0 16.1 16.5 16.7 13.1 32.3 3.5 3.9 36.8 1.4 15.3 19.9 63.2 39.4 20.4 8.9 57.8 35.8 25.6 10.7 16.5 9.5 39.5 66.4 5.6 53.8 8.4 12.1 15.0 14.2 39.4 81.6 3.0 25.7 37.7 33.8 15.0 146.0 23.1 19.6 12.5 15.1 41.2 9.6 25.2 40.4 68.6 1.4 15.1 11.5 14.9 13.1 15.4 26.0 1.2 5.7 3.4 15.3 33.1 48.1 50.6 19.7 51.9 GRAMD1C DKFZp434C0328 ENSG00000178075 "GRAM domain containing 1C" Q8IYS0 3 113828182-113947174 "Predicted intracellular proteins, Predicted membrane proteins" "Lipid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 181.8;Early spermatids: 97.1;Late spermatids: 80.5;Oligodendrocyte precursor cells: 82.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 13 "memory B-cell: 2.7;naive B-cell: 2.9;neutrophil: 2.1" "Group enriched" "Detected in many" 13 "B-cells: 2.9;granulocytes: 2.1" "Cell line enhanced" "Detected in many" "CAPAN-2: 13.5;HUVEC TERT2: 10.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA012316 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane, Cytosol" "HPA012316: AB_1849949" "unprognostic (2.73e-3)" "unprognostic (6.16e-3)" "unprognostic (3.27e-1)" "unprognostic (1.93e-1)" "unprognostic (5.50e-2)" "unprognostic (9.81e-3)" "unprognostic (1.43e-3)" "unprognostic (1.99e-1)" "unprognostic (1.25e-1)" "unprognostic (1.39e-1)" "unprognostic (1.85e-1)" "unprognostic (5.49e-2)" "prognostic favorable (4.22e-15)" "unprognostic (8.48e-2)" "unprognostic (9.96e-2)" "unprognostic (3.61e-2)" "unprognostic (2.09e-2)" 1.4 1.9 13.0 1.7 12.0 0.1 8.8 11.9 15.3 3.1 9.0 5.0 7.6 2.2 2.0 5.5 10.7 2.6 0.7 11.6 12.1 24.0 27.7 4.9 2.0 13.9 15.4 0.8 12.7 10.6 8.1 6.1 11.8 2.6 3.9 14.3 12.0 2.1 0.8 12.1 16.7 0.7 12.3 1.3 9.0 16.8 14.5 1.1 3.9 3.2 3.9 2.0 3.7 10.0 1.6 0.0 4.0 3.0 0.7 1.8 5.2 3.5 3.1 0.7 2.1 0.0 13.5 0.4 1.0 2.0 1.4 1.3 0.7 1.5 1.8 1.9 0.6 0.3 0.1 0.0 1.4 0.2 0.0 3.0 1.0 0.6 0.1 7.1 10.2 4.5 0.0 0.1 1.1 0.4 1.6 0.2 0.3 1.4 0.5 0.0 0.8 2.4 4.2 1.9 0.8 1.1 1.0 5.2 3.4 1.6 3.6 0.0 2.2 1.5 2.8 0.0 0.3 2.2 1.3 1.9 2.2 0.1 1.8 0.0 0.0 0.0 0.1 0.0 0.0 2.7 0.1 0.2 0.0 2.9 0.1 0.1 2.1 0.1 0.0 0.0 0.0 0.0 13.0 12.0 11.9 15.3 11.6 12.1 13.9 15.4 11.8 12.3 14.5 10.0 4.5 12.8 10.5 181.8 15.6 1.0 6.9 3.0 5.2 0.2 9.9 7.0 0.9 15.7 7.1 14.7 37.5 17.5 0.3 10.1 31.3 4.4 97.1 33.3 8.5 4.7 4.9 2.7 29.7 2.7 3.7 1.5 6.6 51.9 0.0 1.4 5.7 17.0 1.5 11.8 4.3 5.5 4.1 0.3 0.8 80.5 2.8 0.9 1.8 9.4 0.1 13.4 0.0 82.4 1.7 2.3 9.3 1.5 6.3 2.8 34.3 14.0 27.9 19.7 0.0 1.2 1.7 28.2 6.7 6.8 4.7 42.4 1.9 5.0 5.3 7.0 GRB7 ENSG00000141738 "Growth factor receptor bound protein 7" Q14451 17 39737927-39747291 "Cancer-related genes, Predicted intracellular proteins" "Repressor, RNA-binding" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 60.2;kidney: 61.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 77.1;Basal squamous epithelial cells: 104.7;Prostatic glandular cells: 79.0;Squamous epithelial cells: 124.7;Syncytiotrophoblasts: 98.6;Urothelial cells: 79.7" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in single" 11 "cerebellum: 5.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "OE19: 1706.0" "Region enhanced" "Detected in many" "cerebellum: 8.3" "Low region specificity" "Detected in many" "CAB005226, HPA057084, CAB073538" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" "Plasma membrane, Cytosol" "CAB005226: AB_2113278, CAB073538: , HPA057084: AB_2683330" "unprognostic (8.46e-2)" "unprognostic (2.06e-2)" "unprognostic (1.45e-1)" "prognostic unfavorable (6.60e-7)" "unprognostic (7.06e-3)" "unprognostic (2.09e-2)" "unprognostic (1.02e-1)" "unprognostic (1.85e-1)" "unprognostic (2.02e-1)" "prognostic unfavorable (3.10e-4)" "prognostic unfavorable (6.90e-4)" "unprognostic (2.59e-2)" "prognostic favorable (8.23e-5)" "unprognostic (1.83e-2)" "unprognostic (4.77e-2)" "unprognostic (5.49e-3)" "unprognostic (4.01e-2)" 5.9 0.1 0.0 0.7 0.4 0.0 14.2 5.6 0.4 13.5 4.5 8.1 11.8 3.3 3.8 60.2 22.3 9.5 1.2 0.2 0.0 61.5 11.1 10.6 0.1 0.0 0.4 1.0 32.7 11.4 6.9 11.9 0.5 14.5 10.0 0.1 25.2 11.6 0.3 39.9 10.8 1.0 0.0 0.5 16.9 1.2 0.1 1.1 6.6 0.1 8.7 7.5 26.2 0.3 12.6 14.4 0.0 0.0 0.0 0.0 19.1 0.0 0.8 0.1 0.5 44.7 24.3 0.0 4.2 0.4 0.9 24.1 0.0 16.1 0.0 0.0 2.1 0.0 6.4 38.5 0.0 0.0 0.0 0.0 15.1 0.2 3.7 2.5 0.1 0.0 0.0 0.0 0.0 11.5 0.2 0.1 4.9 1706.0 3.4 0.1 0.0 18.6 18.5 14.0 9.5 0.1 18.4 370.7 0.1 17.3 14.0 0.0 0.0 0.0 1.1 0.2 0.0 0.2 0.1 1.0 1.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 5.6 0.4 0.2 0.0 0.0 0.4 0.5 0.0 0.1 0.3 0.5 22.4 15.1 0.0 0.9 38.2 77.1 20.0 104.7 0.2 48.2 30.5 2.5 17.2 18.2 22.0 0.0 35.7 0.7 25.6 9.8 35.6 0.0 30.2 5.3 2.6 14.4 0.0 0.3 19.4 27.4 3.1 27.0 41.8 1.3 0.5 0.4 5.1 2.8 0.0 0.0 19.7 40.7 0.0 2.3 0.0 2.8 1.3 5.4 0.0 1.6 0.4 0.0 0.0 0.0 26.7 26.0 1.2 0.3 79.0 28.3 13.8 20.9 0.1 0.0 0.9 2.1 0.4 0.3 124.7 41.9 98.6 1.4 0.0 21.1 79.7 GRIK1 "GluK1, GLUR5" ENSG00000171189 "Glutamate ionotropic receptor kainate type subunit 1" P39086 21 29536933-29940033 "FDA approved drug targets, Predicted membrane proteins" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "adrenal gland: 12.5;brain: 32.6;retina: 38.2" "Group enriched" "Detected in some" 10 "Inhibitory neurons: 2260.1;Oligodendrocyte precursor cells: 862.5" "Cancer enriched" "Detected in some" 5 "glioma: 4.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "Daudi: 1.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014623, HPA073879" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA014623: AB_1850305, HPA073879: " "unprognostic (1.39e-1)" "unprognostic (6.54e-2)" "unprognostic (1.32e-1)" "unprognostic (1.04e-2)" "unprognostic (1.03e-3)" "unprognostic (1.56e-1)" "unprognostic (1.07e-1)" "unprognostic (2.12e-3)" "unprognostic (1.25e-1)" "unprognostic (8.77e-2)" "unprognostic (4.89e-3)" "unprognostic (1.20e-3)" "unprognostic (1.47e-8)" "unprognostic (2.09e-1)" "unprognostic (2.68e-1)" "unprognostic (1.09e-1)" "unprognostic (3.15e-3)" 0.2 12.5 7.5 0.2 6.6 0.1 1.8 2.4 6.0 0.8 0.0 0.3 0.0 0.1 2.0 0.3 0.0 0.1 0.0 8.4 12.3 0.0 0.1 0.1 0.1 30.0 11.2 0.3 0.0 0.0 0.2 0.4 32.6 2.4 0.5 38.2 0.0 0.1 0.1 0.8 0.4 0.1 2.6 0.1 0.2 0.5 9.7 0.0 0.0 0.0 0.0 0.4 0.4 2.9 0.0 0.1 0.2 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.2 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.1 0.2 0.0 0.1 0.1 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 7.5 6.6 2.4 6.0 8.4 12.3 30.0 11.2 32.6 2.6 9.7 2.9 0.1 0.0 0.0 27.4 0.0 0.3 0.0 0.0 0.0 149.8 2.3 0.3 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 5.8 0.1 1.2 0.4 0.0 0.0 29.8 0.0 0.0 0.7 0.0 0.2 0.0 148.8 0.0 0.0 0.1 1.7 2260.1 0.0 0.0 0.0 0.4 13.2 0.3 0.2 3.6 10.3 0.0 2.5 0.0 862.5 8.9 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 4.9 0.0 0.0 5.7 0.0 0.0 0.0 0.1 0.0 0.1 33.8 0.1 0.0 GRIK5 "GluK5, GRIK2, KA2" ENSG00000105737 "Glutamate ionotropic receptor kainate type subunit 5" Q16478 19 41998321-42069498 "FDA approved drug targets, Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel, Ligand-gated ion channel, Receptor" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;testis: 32.9" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Bipolar cells: 23.0;Excitatory neurons: 32.4;Horizontal cells: 18.5;Inhibitory neurons: 31.1;Oligodendrocyte precursor cells: 31.7;Rod photoreceptor cells: 21.2" "Group enriched" "Detected in many" 5 "glioma: 15.4;ovarian cancer: 6.6;thyroid cancer: 6.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HEL: 13.7;hTERT-RPE1: 21.2;NTERA-2: 13.1;REH: 37.5;SCLC-21H: 10.3;SH-SY5Y: 22.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA074001 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 14: REH - Unknown function" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA074001: AB_2732248" "unprognostic (4.99e-2)" "unprognostic (3.40e-1)" "unprognostic (1.30e-3)" "unprognostic (6.68e-3)" "unprognostic (4.28e-2)" "unprognostic (3.86e-1)" "unprognostic (5.82e-1)" "unprognostic (2.23e-1)" "unprognostic (3.89e-2)" "unprognostic (1.73e-2)" "prognostic favorable (7.23e-4)" "unprognostic (8.43e-2)" "prognostic unfavorable (9.32e-4)" "unprognostic (6.47e-3)" "unprognostic (5.77e-2)" "unprognostic (4.57e-2)" "unprognostic (6.12e-2)" 1.6 4.0 20.0 1.7 17.3 3.0 1.2 6.2 26.7 5.3 0.1 16.4 0.7 7.3 1.8 1.6 6.8 1.9 4.9 36.5 15.5 7.0 0.3 0.5 0.7 3.6 4.8 3.6 2.7 14.8 18.3 0.0 7.0 6.2 1.0 12.5 0.7 6.5 0.5 0.9 3.4 5.2 3.0 1.3 5.3 32.9 14.6 0.9 11.3 0.7 0.6 5.0 2.7 6.6 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.2 0.1 0.0 0.2 0.2 0.0 0.0 0.4 0.3 13.7 0.0 0.0 0.3 0.0 0.0 0.2 0.1 0.1 0.0 21.2 0.0 0.6 0.1 0.6 0.0 0.2 0.2 0.0 13.1 0.1 0.0 37.5 0.0 0.1 5.8 0.1 10.3 22.7 0.1 0.0 0.2 0.6 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 1.4 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.0 17.3 6.2 26.7 36.5 15.5 3.6 4.8 7.0 3.0 14.6 6.6 0.2 0.0 0.0 17.9 0.1 0.4 0.1 0.0 0.0 23.0 0.2 0.8 3.1 0.0 0.0 1.8 2.1 0.0 0.0 0.1 0.0 0.8 1.6 0.2 0.2 0.4 0.0 0.0 32.4 0.0 0.0 0.6 0.0 0.3 4.5 7.2 0.0 0.0 0.0 18.5 31.1 0.0 0.0 0.0 0.0 2.3 0.9 0.1 0.0 2.8 0.0 9.1 0.0 31.7 0.9 0.1 0.0 0.4 0.0 0.4 0.0 0.0 0.0 21.2 0.0 4.9 1.7 4.2 2.2 0.2 0.4 0.0 0.0 0.0 0.0 0.1 GRK3 "ADRBK2, BARK2" ENSG00000100077 "G protein-coupled receptor kinase 3" P35626 22 25564675-25729294 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 30.2" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 32.2;Club cells: 16.7;Extravillous trophoblasts: 29.2;granulocytes: 18.9;Hofbauer cells: 29.3;Macrophages: 26.4;monocytes: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 9 "classical monocyte: 4.1;eosinophil: 5.2;intermediate monocyte: 7.2;memory B-cell: 4.1;myeloid DC: 3.2;naive B-cell: 5.0;non-classical monocyte: 6.8;plasmacytoid DC: 2.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 43.6;JURKAT: 69.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA000804 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 2: Immune cells - Immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA000804: AB_1078281" "unprognostic (1.02e-1)" "unprognostic (4.38e-2)" "unprognostic (5.68e-3)" "unprognostic (4.33e-2)" "unprognostic (2.09e-1)" "unprognostic (3.67e-2)" "unprognostic (3.29e-1)" "unprognostic (1.78e-2)" "unprognostic (1.97e-1)" "unprognostic (3.54e-1)" "unprognostic (1.95e-3)" "unprognostic (5.79e-2)" "unprognostic (1.01e-3)" "unprognostic (1.74e-1)" "unprognostic (2.87e-3)" "unprognostic (1.89e-2)" "prognostic favorable (1.29e-4)" 30.2 5.4 6.5 12.9 8.9 7.8 9.4 2.3 14.7 4.0 0.0 3.1 2.8 5.3 1.3 2.4 8.7 4.7 4.3 18.9 2.6 2.4 3.2 9.4 15.1 5.4 6.2 2.9 7.1 4.2 3.2 4.4 2.5 7.5 3.9 4.8 3.2 1.6 0.9 3.3 4.7 5.9 2.9 18.8 3.8 15.7 7.6 10.2 4.1 1.2 15.6 6.2 1.5 6.0 0.1 3.9 11.9 3.9 8.1 1.0 17.3 1.3 3.8 3.8 6.5 6.4 6.8 22.5 0.3 0.3 10.5 0.2 11.9 9.1 11.1 43.6 7.6 10.3 1.3 14.3 0.3 33.8 16.8 2.0 6.2 2.6 4.6 0.6 0.7 69.4 1.1 0.1 4.4 5.6 24.4 2.4 8.5 12.1 0.0 10.8 18.9 3.8 0.0 6.6 27.6 37.5 2.2 0.1 9.0 10.9 3.3 13.4 0.3 0.1 23.6 0.2 4.9 2.6 9.1 17.4 15.8 11.8 3.7 0.5 4.1 5.2 0.0 7.2 0.2 4.1 0.0 0.2 3.2 5.0 0.1 0.1 0.2 0.0 6.8 2.7 0.3 1.5 6.5 8.9 2.3 14.7 18.9 2.6 5.4 6.2 2.5 2.9 7.6 6.0 3.9 16.0 32.2 0.0 10.2 0.0 0.0 0.0 0.0 0.0 11.7 9.5 0.0 0.0 16.7 0.0 0.0 2.0 1.1 0.0 1.9 9.4 0.0 12.7 5.8 2.4 0.0 0.0 0.0 1.8 29.2 4.1 0.0 2.2 18.9 3.7 0.0 0.0 29.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 26.4 0.0 0.0 27.4 0.0 0.0 0.0 0.0 3.4 0.0 0.0 2.1 0.0 0.0 1.8 6.6 0.0 0.0 0.0 5.1 0.0 0.0 0.0 0.0 3.3 1.1 5.0 0.0 0.0 GRK4 "GPRK2L, GPRK4" ENSG00000125388 "G protein-coupled receptor kinase 4" P32298 4 2963571-3040760 "Enzymes, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 19.3;testis: 42.3" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 123.0;Early spermatids: 357.7;Late spermatids: 500.3;Spermatocytes: 180.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA057023 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA057023: AB_2683313" "unprognostic (1.86e-2)" "unprognostic (2.88e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (3.65e-1)" "unprognostic (1.84e-1)" "unprognostic (1.21e-1)" "unprognostic (2.39e-1)" "unprognostic (1.79e-1)" "unprognostic (1.87e-1)" "unprognostic (3.90e-4)" "unprognostic (3.20e-1)" "unprognostic (1.01e-2)" "unprognostic (4.74e-2)" "unprognostic (2.17e-1)" "unprognostic (1.17e-1)" "unprognostic (1.89e-1)" 2.8 3.3 6.2 1.1 6.2 1.3 2.4 19.3 8.4 3.0 0.3 2.8 1.0 2.7 2.3 1.8 2.1 2.4 4.9 6.5 5.7 2.2 2.0 2.0 1.2 6.0 5.5 3.5 5.4 4.4 6.2 1.6 5.7 2.0 1.4 10.1 2.9 2.1 4.8 2.3 1.4 2.1 3.6 1.4 3.0 42.3 6.4 1.6 3.3 4.4 1.2 2.3 2.2 7.2 2.3 0.8 2.7 7.9 6.3 6.1 1.6 4.3 1.9 2.4 2.1 2.3 0.7 5.1 1.9 7.1 4.8 0.7 3.6 3.6 2.1 3.4 3.4 5.6 3.2 2.6 3.8 2.3 1.9 4.1 5.7 4.3 2.0 2.7 4.7 5.5 5.4 6.6 5.8 2.6 4.8 4.8 2.1 3.3 6.0 6.1 3.4 2.1 2.3 2.9 15.2 4.8 2.7 1.2 4.1 1.9 6.0 3.5 5.5 6.6 1.7 4.5 4.0 6.5 4.0 3.8 3.3 5.0 2.2 2.1 0.3 0.6 0.3 0.7 0.4 0.3 0.2 0.2 0.1 0.3 0.5 0.4 1.1 0.5 0.2 0.7 0.1 0.4 6.2 6.2 19.3 8.4 6.5 5.7 6.0 5.5 5.7 3.6 6.4 7.2 3.9 3.2 7.4 34.6 2.1 11.2 3.2 5.0 7.4 57.1 5.0 5.5 11.4 4.3 5.6 3.7 123.0 2.1 4.7 0.8 13.7 2.7 357.7 4.2 7.2 4.2 10.3 8.6 53.9 3.8 5.3 8.7 5.1 3.8 5.7 75.0 6.1 3.0 3.4 18.5 71.1 2.4 4.1 2.9 4.6 500.3 13.1 3.1 7.2 9.4 3.0 11.4 2.1 48.2 29.3 2.1 0.4 8.2 5.3 1.8 2.0 5.0 1.2 58.2 6.6 8.4 5.7 180.4 22.3 6.5 11.4 3.0 4.0 34.6 1.3 2.4 GTSE1 "B99, GTSE-1" ENSG00000075218 "G2 and S-phase expressed 1" Q9NYZ3 22 46296870-46330810 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "bone marrow: 11.2;lymphoid tissue: 19.6" "Cell type enhanced" "Detected in many" "Erythroid cells: 52.2;Extravillous trophoblasts: 31.2;Granulosa cells: 27.1;Spermatocytes: 73.6;Spermatogonia: 27.8" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected" "Not detected" HPA029457 Approved "Plasma membrane,Centrosome" Yes Yes "Cluster 45: Eosinophils - Innate immune response" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" Centrosome "Plasma membrane" "HPA029457: " "unprognostic (1.97e-1)" "unprognostic (3.07e-2)" "unprognostic (1.71e-3)" "unprognostic (2.59e-1)" "unprognostic (7.16e-2)" "unprognostic (2.40e-2)" "prognostic unfavorable (1.90e-10)" "prognostic unfavorable (4.66e-4)" "unprognostic (1.09e-1)" "unprognostic (8.37e-2)" "prognostic unfavorable (1.29e-4)" "unprognostic (3.49e-3)" "unprognostic (0.00e+0)" "unprognostic (6.52e-3)" "unprognostic (3.25e-1)" "unprognostic (1.14e-1)" "unprognostic (4.85e-2)" 0.6 0.6 0.2 5.1 0.2 11.2 0.5 0.5 0.3 0.7 0.2 2.4 4.1 0.8 0.0 3.6 0.2 0.5 0.3 0.2 0.3 0.3 0.4 0.6 9.2 0.4 0.3 0.2 0.2 0.1 0.1 2.6 0.4 0.2 2.6 0.1 0.7 0.1 0.1 2.5 2.9 1.2 0.1 2.4 1.9 7.2 0.5 19.6 0.2 0.2 8.7 1.0 1.2 0.4 59.5 27.6 53.2 42.2 1.1 3.0 25.5 50.3 23.5 71.7 58.8 29.3 21.9 55.7 13.0 19.4 32.8 30.3 48.0 12.7 45.7 33.7 52.0 37.4 38.9 22.8 0.1 67.5 43.8 0.6 1.0 30.9 15.6 7.5 31.2 39.7 29.0 67.8 43.4 33.1 60.9 33.0 37.2 24.2 30.7 59.6 59.7 36.3 11.7 10.7 27.5 37.5 48.1 30.7 21.5 23.8 26.2 25.8 25.1 40.6 75.8 33.4 53.7 38.6 19.7 56.3 25.8 32.2 60.5 0.0 0.0 0.3 0.3 0.0 0.0 0.3 0.1 0.1 0.0 0.1 0.0 0.0 0.5 0.3 0.0 0.4 0.3 0.2 0.2 0.2 0.5 0.3 0.2 0.3 0.4 0.3 0.4 0.1 0.5 0.4 1.1 0.0 0.0 0.7 7.0 2.8 1.1 2.1 0.6 0.7 2.8 3.4 1.6 0.0 0.5 0.0 0.0 19.2 6.8 7.6 0.0 0.9 5.6 2.1 4.7 3.9 1.2 52.2 0.3 0.2 31.2 5.1 16.8 4.3 0.0 27.1 6.4 1.2 19.9 0.0 0.5 9.4 2.0 7.5 4.0 3.9 0.3 4.7 0.0 0.0 0.1 0.4 0.0 0.5 0.1 0.8 0.2 0.7 19.1 1.8 0.5 0.5 0.2 0.3 6.6 2.6 5.4 73.6 27.8 11.7 2.6 1.5 5.0 1.2 13.8 1.6 HAPLN3 "EXLD1, HsT19883" ENSG00000140511 "Hyaluronan and proteoglycan link protein 3" Q96S86 15 88877294-88895597 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 9 "Extravillous trophoblasts: 966.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 50.9" "Lineage enriched" "Detected in all" 5 "T-cells: 50.9" "Cell line enhanced" "Detected in many" "HDLM-2: 34.7;U-2 OS: 31.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA039237 Approved Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 64: Macrophages - Immune response" "Cluster 9: U-2 OS - Unknown function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA039237: AB_10805357" "unprognostic (1.67e-2)" "unprognostic (1.04e-3)" "unprognostic (2.57e-1)" "unprognostic (2.53e-2)" "unprognostic (3.27e-1)" "unprognostic (2.24e-2)" "unprognostic (4.21e-1)" "unprognostic (3.82e-1)" "unprognostic (3.37e-3)" "unprognostic (7.37e-3)" "unprognostic (1.13e-3)" "unprognostic (4.30e-1)" "prognostic unfavorable (4.18e-13)" "unprognostic (1.95e-1)" "unprognostic (3.01e-2)" "unprognostic (6.12e-2)" "unprognostic (1.12e-1)" 10.3 1.9 2.1 11.5 2.0 3.1 8.6 1.9 2.7 5.1 2.1 3.2 0.6 4.3 0.1 6.1 6.2 2.7 4.6 2.1 2.0 6.1 0.9 9.7 11.7 2.4 2.1 2.7 1.4 0.5 2.2 1.4 2.5 5.7 0.4 4.2 6.0 0.7 3.6 6.2 4.6 2.7 2.3 5.7 3.5 1.0 2.4 2.9 4.6 0.6 3.2 6.9 5.6 2.1 2.0 7.0 1.3 15.4 4.4 4.2 4.7 4.4 1.0 1.6 2.0 4.4 6.4 0.0 11.9 5.4 2.5 1.7 14.7 1.9 0.0 34.7 12.9 4.9 0.3 0.0 0.6 0.0 0.1 1.6 0.8 3.0 0.2 0.2 7.1 0.6 0.1 9.3 0.8 0.2 0.1 0.0 11.2 0.0 0.2 0.0 0.6 11.5 2.9 0.1 0.1 4.2 0.9 0.7 6.1 1.9 0.0 0.6 1.3 10.8 31.2 8.1 0.7 1.1 0.1 0.1 3.8 0.0 9.3 1.4 1.1 0.0 1.2 0.8 5.4 0.2 18.3 7.4 2.2 1.5 18.3 8.6 0.3 10.1 0.2 0.8 50.9 5.9 2.1 2.0 1.9 2.7 2.1 2.0 2.4 2.1 2.5 2.3 2.4 2.1 16.0 0.0 3.4 1.3 4.0 32.0 10.8 13.5 4.6 2.5 47.1 42.4 9.3 1.5 10.4 1.8 10.4 5.8 3.2 0.5 0.0 5.3 0.0 6.3 3.7 29.4 0.0 0.0 1.3 2.0 966.2 8.5 1.5 12.1 1.3 2.5 3.3 0.1 19.3 0.0 0.1 0.9 6.1 0.3 22.0 0.2 0.9 3.0 17.8 2.8 9.7 3.8 3.1 0.5 0.1 9.9 0.1 0.7 0.5 10.4 0.0 0.2 2.7 103.8 13.1 7.2 24.5 0.3 2.1 6.3 24.2 20.4 9.4 0.2 0.5 7.8 HARBI1 "C11orf77, FLJ32675" ENSG00000180423 "Harbinger transposase derived 1" Q96MB7 11 46602861-46617909 "Predicted intracellular proteins" "Hydrolase, Nuclease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 4 "Early spermatids: 70.9;Late spermatids: 73.0;Spermatocytes: 25.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038671, HPA045457" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA038671: AB_10675947, HPA045457: AB_2679332" "unprognostic (1.29e-1)" "unprognostic (6.82e-2)" "unprognostic (7.76e-2)" "unprognostic (2.65e-1)" "unprognostic (1.61e-1)" "unprognostic (3.95e-1)" "unprognostic (1.23e-5)" "unprognostic (2.10e-1)" "unprognostic (1.66e-2)" "unprognostic (9.58e-2)" "unprognostic (3.15e-1)" "unprognostic (6.34e-2)" "unprognostic (6.96e-2)" "unprognostic (1.47e-1)" "unprognostic (1.66e-1)" "unprognostic (5.01e-2)" "unprognostic (1.13e-1)" 2.0 2.6 2.6 2.4 4.5 5.6 2.4 3.3 4.2 2.3 2.3 3.0 2.6 1.7 3.4 2.3 2.1 2.0 2.5 2.7 3.1 2.9 3.3 2.2 3.4 3.5 3.5 1.4 2.4 2.2 2.5 2.8 3.6 2.2 3.4 2.7 2.8 1.9 2.6 3.2 2.8 3.0 2.8 2.4 4.0 12.1 4.0 4.2 2.7 2.0 3.4 2.6 1.5 7.3 3.3 5.3 4.3 4.1 8.4 5.1 5.1 4.7 4.5 6.3 8.0 3.7 3.7 5.8 2.9 3.9 7.1 6.3 4.6 4.1 5.9 6.7 5.5 5.9 3.9 4.2 9.8 5.5 7.6 6.5 10.7 4.2 8.2 2.4 4.0 6.2 9.4 7.0 5.3 7.1 6.8 2.3 11.8 10.8 6.4 4.5 6.1 10.3 4.8 3.9 4.1 3.4 5.6 5.9 6.8 5.7 9.9 4.7 3.8 6.3 4.9 8.4 4.3 6.6 7.7 6.3 4.8 3.2 6.6 21.9 7.6 10.9 9.6 10.3 6.7 4.7 7.6 7.0 6.4 6.6 7.2 8.0 11.2 6.9 9.8 8.3 10.2 4.4 2.6 4.5 3.3 4.2 2.7 3.1 3.5 3.5 3.6 2.8 4.0 7.3 1.0 0.0 1.3 1.3 2.2 1.0 2.7 4.0 1.8 3.5 2.5 1.8 2.3 1.5 4.4 0.0 2.1 4.9 1.5 2.1 5.9 4.1 70.9 4.7 2.2 1.4 1.2 13.5 1.5 2.2 3.4 1.7 2.0 4.7 0.0 1.6 1.8 2.8 3.3 3.3 1.5 2.2 8.2 3.3 0.8 73.0 3.1 1.7 1.8 0.0 4.2 2.9 1.0 0.5 4.6 3.0 0.8 1.9 3.4 1.6 3.4 3.5 6.1 3.7 0.0 2.1 2.0 25.2 13.5 1.7 2.7 9.3 2.2 2.2 1.7 2.3 HAS1 HAS ENSG00000105509 "Hyaluronan synthase 1" Q92839 19 51713112-51723991 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 49.6;ovary: 20.8" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 26.6;Bipolar cells: 20.3;Cholangiocytes: 38.6;Fibroblasts: 64.2;Suprabasal keratinocytes: 17.8" "Cancer enhanced" "Detected in some" "pancreatic cancer: 2.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 4 "eosinophil: 2.5" "Lineage enriched" "Detected in single" 18 "granulocytes: 2.5" "Cell line enriched" "Detected in some" 4 "U-87 MG: 112.6" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA067602 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Nucleoplasm "HPA067602: AB_2685871" "unprognostic (3.56e-2)" "unprognostic (1.19e-1)" "unprognostic (4.43e-2)" "unprognostic (5.26e-4)" "unprognostic (7.17e-3)" "unprognostic (7.05e-2)" "unprognostic (1.02e-1)" "unprognostic (5.49e-4)" "unprognostic (4.80e-2)" "unprognostic (1.99e-2)" "unprognostic (8.43e-2)" "unprognostic (1.72e-1)" "unprognostic (2.30e-11)" "unprognostic (9.12e-4)" "unprognostic (8.99e-2)" "unprognostic (3.73e-4)" "unprognostic (2.43e-2)" 49.6 0.5 1.4 6.3 1.1 3.6 1.3 1.1 1.1 0.1 0.0 2.8 0.1 1.0 0.0 0.8 9.0 5.5 9.2 0.9 2.0 0.5 0.6 3.7 0.0 1.8 0.8 20.8 2.1 0.3 0.9 0.3 0.7 0.2 0.5 0.2 0.2 0.0 0.2 5.4 1.3 0.7 0.3 0.3 1.7 0.3 2.2 0.1 0.7 0.0 0.0 6.3 0.6 1.3 0.0 0.5 0.0 0.0 0.2 0.6 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 3.2 0.0 27.0 0.0 0.1 0.0 0.0 0.0 0.2 6.8 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.4 0.0 0.3 0.8 0.0 0.0 0.0 0.0 112.6 0.0 0.2 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.4 1.1 1.1 1.1 0.9 2.0 1.8 0.8 0.7 0.3 2.2 1.3 1.5 0.0 1.8 0.0 0.2 26.6 0.1 0.8 0.6 20.3 0.0 0.0 1.3 38.6 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.1 0.5 0.5 0.0 0.0 1.7 0.0 0.2 64.2 2.6 0.0 2.5 0.0 0.0 0.1 0.2 0.0 1.5 0.0 0.0 0.8 9.0 0.2 0.3 8.3 8.8 0.0 0.0 0.2 0.0 0.0 0.9 0.1 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.5 0.0 3.1 10.6 0.1 0.5 0.4 17.8 0.1 0.3 0.0 0.0 0.2 HAUS7 "UCHL5IP, UIP1" ENSG00000213397 "HAUS augmin like complex subunit 7" Q99871 X 153447666-153495516 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 45.4;Oligodendrocyte precursor cells: 31.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003614 Approved "Plasma membrane,Centrosome" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 57: Non-specific - Angiogenesis" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Centrosome" "HPA003614: AB_1080368" "unprognostic (2.06e-1)" "prognostic favorable (6.12e-4)" "unprognostic (3.81e-2)" "unprognostic (3.21e-2)" "unprognostic (5.84e-3)" "unprognostic (5.52e-2)" "unprognostic (1.75e-2)" "unprognostic (7.50e-2)" "unprognostic (1.56e-1)" "unprognostic (3.39e-1)" "unprognostic (4.65e-3)" "unprognostic (6.28e-2)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.98e-1)" "unprognostic (1.15e-1)" "unprognostic (4.25e-2)" "unprognostic (1.09e-2)" 19.0 13.0 29.1 9.2 31.3 11.0 16.2 26.3 54.0 42.3 24.3 15.9 7.1 17.8 15.1 11.4 21.3 13.2 23.5 32.3 26.3 25.2 13.6 19.5 14.4 28.3 27.0 16.0 8.2 5.0 11.9 12.3 28.4 22.5 5.8 3.0 12.5 17.9 12.0 44.7 13.3 11.5 26.4 28.5 11.5 12.6 29.0 10.4 19.2 9.2 9.5 17.4 21.7 32.3 28.2 44.9 24.1 51.2 8.9 14.1 37.2 17.8 12.1 30.1 51.4 36.2 17.3 25.5 59.2 18.5 43.1 32.0 39.6 29.4 15.6 23.6 59.6 19.3 33.5 26.9 9.3 26.9 35.5 21.1 7.4 29.5 16.4 13.1 22.4 32.5 21.7 17.6 15.7 68.9 41.7 60.5 15.7 67.5 65.8 36.5 30.2 47.0 10.2 17.3 25.1 20.5 10.3 27.4 9.6 8.9 10.8 20.8 10.7 27.1 42.9 50.8 36.1 24.0 33.7 97.6 11.7 68.9 34.6 14.8 53.2 22.7 32.6 66.7 34.5 44.0 36.1 33.6 46.7 36.5 35.2 32.2 6.7 39.1 62.0 26.0 33.8 34.3 29.1 31.3 26.3 54.0 32.3 26.3 28.3 27.0 28.4 26.4 29.0 32.3 9.4 6.4 8.1 45.4 5.3 7.1 1.6 3.6 1.2 2.1 2.7 3.0 2.5 4.3 2.6 0.0 4.2 12.6 6.0 9.3 5.9 10.4 0.1 1.0 1.8 5.6 2.4 6.6 11.9 8.0 24.6 6.3 3.6 0.7 19.7 1.6 15.4 4.2 12.2 3.3 4.9 13.8 4.1 10.0 6.8 0.5 5.9 5.0 3.6 4.7 13.4 2.0 12.3 31.7 3.5 7.4 7.7 7.5 2.5 3.3 6.9 14.9 3.5 1.9 6.6 1.9 6.5 2.2 6.7 1.3 4.7 9.3 4.9 1.7 14.9 1.5 HCLS1 "CTTNL, HS1" ENSG00000180353 "Hematopoietic cell-specific Lyn substrate 1" P14317 3 121631399-121660927 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 153.6;lymphoid tissue: 300.3" "Cell type enhanced" "Detected in many" "B-cells: 175.7;Kupffer cells: 666.3;Macrophages: 269.0;monocytes: 245.7;NK-cells: 216.3;T-cells: 181.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 265.6;HMC-1: 362.3;RPMI-8226: 256.5;THP-1: 262.8;U-266/70: 361.6;U-698: 371.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019143 Enhanced Supported "Plasma membrane,Cytosol" NA NA 870000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA019143: AB_1850532" "unprognostic (2.27e-2)" "unprognostic (1.79e-3)" "unprognostic (5.38e-3)" "unprognostic (6.29e-2)" "unprognostic (1.01e-2)" "unprognostic (4.02e-3)" "unprognostic (2.35e-1)" "unprognostic (4.88e-3)" "unprognostic (1.70e-2)" "unprognostic (1.19e-1)" "unprognostic (6.76e-2)" "unprognostic (2.28e-1)" "unprognostic (1.03e-3)" "unprognostic (2.93e-1)" "unprognostic (3.46e-2)" "unprognostic (2.60e-2)" "unprognostic (2.01e-1)" 67.0 32.9 14.6 147.2 14.7 153.6 25.5 15.4 18.7 20.7 15.8 29.2 21.2 13.7 6.4 15.7 21.5 37.8 18.4 14.3 17.0 21.5 39.1 52.7 207.6 21.6 17.5 9.4 11.9 7.7 14.6 51.4 20.8 15.8 31.4 2.3 16.0 11.1 7.3 11.1 68.7 34.6 18.5 300.3 27.1 4.5 18.2 140.3 15.4 18.8 242.8 53.0 13.7 23.0 0.8 0.0 0.2 0.1 20.9 11.5 5.7 4.1 4.0 0.8 1.6 0.1 0.0 265.6 124.6 0.0 0.2 0.3 6.9 9.9 1.1 120.6 0.0 172.6 0.0 0.0 11.6 192.4 362.3 2.2 0.5 0.0 1.5 0.0 153.4 106.2 35.1 235.9 0.0 0.0 137.9 162.9 0.3 0.2 4.5 137.1 0.2 256.5 0.0 68.0 0.3 0.2 0.2 0.4 0.6 0.6 0.1 262.8 203.5 0.0 2.0 0.3 0.9 361.6 118.1 371.5 1.9 181.5 0.2 357.3 713.1 1180.9 405.3 870.4 333.0 345.7 334.2 376.8 636.2 313.1 279.3 326.2 1619.2 280.0 997.1 197.4 494.2 1427.9 14.6 14.7 15.4 18.7 14.3 17.0 21.6 17.5 20.8 18.5 18.2 23.0 23.0 9.6 31.8 1.0 175.7 3.2 1.0 7.8 0.6 0.5 2.7 5.1 2.3 4.3 13.1 0.0 0.0 122.4 139.5 0.8 0.0 0.3 1.1 8.8 1.6 23.3 0.0 50.5 1.4 0.2 60.0 7.0 8.6 3.1 73.4 0.7 27.8 7.7 126.9 0.0 0.7 0.4 4.1 666.3 105.8 1.5 3.4 269.0 19.6 26.2 245.7 0.4 216.3 0.5 0.3 0.2 0.2 1.2 148.6 0.4 0.1 0.9 24.7 0.8 13.1 3.7 6.7 0.6 0.6 1.3 4.4 145.4 181.4 2.4 0.5 2.2 HEG1 "HEG, KIAA1237" ENSG00000173706 "Heart development protein with EGF like domains 1" Q9ULI3 3 124965710-125055997 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 90.1;Cardiomyocytes: 90.5;Cone photoreceptor cells: 264.8;Endothelial cells: 121.5;Hepatic stellate cells: 130.3;Microglial cells: 92.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 174.1;HHSteC: 241.5;hTERT-RPE1: 351.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010952, HPA011559" Approved Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 510000000 "Cluster 15: NK-cells - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA010952: AB_2668389, HPA011559: AB_1850580" "unprognostic (1.10e-1)" "unprognostic (2.21e-1)" "unprognostic (6.52e-2)" "unprognostic (2.23e-1)" "unprognostic (1.30e-1)" "unprognostic (5.40e-2)" "unprognostic (6.48e-2)" "unprognostic (2.89e-2)" "unprognostic (2.36e-1)" "unprognostic (9.80e-2)" "unprognostic (1.69e-1)" "unprognostic (8.33e-2)" "prognostic unfavorable (1.93e-5)" "unprognostic (1.11e-2)" "unprognostic (4.99e-2)" "unprognostic (6.20e-3)" "prognostic unfavorable (1.16e-4)" 30.1 9.9 19.3 19.2 23.2 1.9 14.8 27.0 15.0 20.8 28.3 11.9 8.0 19.2 6.2 16.1 13.2 38.9 67.3 14.3 22.7 15.2 7.5 55.1 16.5 32.0 28.1 12.4 31.6 16.1 3.6 33.4 28.6 13.9 12.2 46.8 7.7 14.6 14.3 5.2 9.4 25.4 27.3 17.9 9.8 13.5 30.3 8.6 52.2 24.2 15.7 30.0 10.1 30.6 7.0 7.1 54.7 4.2 73.2 58.7 21.1 64.9 90.1 72.6 83.5 58.5 1.0 2.8 43.8 174.1 52.3 15.3 7.4 31.6 97.9 6.5 3.7 1.3 42.3 8.4 241.5 1.8 80.6 77.8 10.1 87.4 21.5 351.3 69.3 5.0 0.1 1.0 25.7 1.3 2.8 0.1 10.1 0.1 5.5 4.8 41.0 0.2 14.6 1.2 1.0 5.6 134.8 10.6 6.4 55.1 24.2 4.3 93.9 37.7 41.3 150.5 29.1 6.9 19.7 0.4 76.8 6.5 82.4 1.1 0.1 0.0 1.9 1.7 1.1 0.5 0.6 1.7 0.4 0.3 1.2 0.8 0.0 3.9 1.9 0.4 0.2 0.5 19.3 23.2 27.0 15.0 14.3 22.7 32.0 28.1 28.6 27.3 30.3 30.6 90.1 86.6 5.8 28.7 4.9 5.0 8.0 25.4 6.8 6.1 2.4 5.7 90.5 7.2 6.5 27.6 264.8 1.8 19.2 0.5 0.0 32.0 7.0 4.0 20.1 121.5 0.0 6.1 0.9 6.4 65.3 44.8 1.1 2.2 26.6 24.9 130.3 3.5 6.8 1.7 14.9 0.5 4.1 18.4 7.3 9.4 5.0 7.1 7.2 92.8 4.0 6.0 35.0 13.0 57.6 6.4 0.1 13.9 8.6 5.2 0.8 1.3 1.0 66.8 0.0 24.0 28.7 1.0 1.1 2.7 4.4 3.3 14.2 3.1 0.1 1.3 HELB ENSG00000127311 "DNA helicase B" Q8NG08 12 66302493-66343643 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair" "Helicase, Hydrolase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enhanced" "Detected in many" "dendritic cells: 32.8;T-cells: 43.5" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "A549: 2.7;HDLM-2: 2.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052461 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" "Nucleoplasm, Plasma membrane" "HPA052461: " "unprognostic (1.33e-1)" "unprognostic (1.67e-1)" "unprognostic (1.97e-1)" "unprognostic (9.06e-3)" "unprognostic (8.65e-2)" "unprognostic (1.34e-2)" "unprognostic (2.00e-1)" "unprognostic (5.22e-2)" "unprognostic (1.20e-1)" "unprognostic (2.13e-1)" "unprognostic (1.10e-1)" "unprognostic (2.45e-1)" "unprognostic (1.39e-6)" "unprognostic (3.97e-3)" "unprognostic (9.19e-4)" "unprognostic (1.93e-1)" "unprognostic (9.50e-3)" 0.8 0.3 0.1 0.4 0.1 1.0 0.7 0.1 0.3 0.5 0.2 0.7 0.0 0.4 0.0 0.6 0.5 0.1 0.4 0.1 0.1 0.7 1.2 1.1 0.5 0.4 0.2 0.8 0.9 0.1 1.2 0.0 0.3 0.8 0.1 0.1 0.8 0.0 0.2 0.5 1.2 0.1 0.2 1.8 0.8 0.4 0.3 0.4 0.7 0.0 0.3 0.5 0.6 0.4 0.4 2.7 0.2 0.6 0.1 0.1 0.5 0.6 0.1 0.6 1.2 0.6 1.5 1.0 0.9 0.1 0.9 0.8 0.5 0.2 0.3 2.6 0.2 0.8 2.1 0.0 0.0 0.0 0.5 0.0 0.0 0.7 0.1 0.2 0.1 1.3 0.6 1.1 0.4 1.1 0.0 0.2 0.0 1.1 0.5 0.2 1.0 0.2 0.0 0.0 0.1 0.3 1.7 0.2 0.4 0.4 0.3 1.7 0.2 0.2 0.5 0.3 0.5 1.2 1.0 0.5 0.1 0.9 0.4 4.5 0.8 5.8 2.6 0.5 4.2 0.4 4.9 3.9 1.7 0.7 5.1 4.1 0.7 3.5 0.2 0.6 5.6 1.0 0.1 0.1 0.1 0.3 0.1 0.1 0.4 0.2 0.3 0.2 0.3 0.4 14.7 0.0 7.5 1.3 14.0 0.6 2.5 0.6 10.8 3.2 10.3 9.8 4.0 0.0 6.6 0.0 12.5 3.0 32.8 4.3 1.9 1.7 0.5 12.6 11.5 9.9 4.8 6.1 7.7 1.1 2.5 5.7 11.7 20.9 2.5 10.3 4.6 2.8 3.3 13.5 5.2 5.6 2.0 5.5 3.3 0.8 3.4 10.3 3.6 20.6 8.0 2.4 14.4 0.0 16.2 2.4 3.0 0.7 21.7 5.8 5.9 3.2 3.4 6.5 0.0 11.3 8.0 1.2 1.5 5.2 1.7 2.5 43.5 9.2 6.4 1.8 HENMT1 "C1orf59, FLJ30525, HEN1" ENSG00000162639 "HEN methyltransferase 1" Q5T8I9 1 108648290-108661526 "Enzymes, Predicted intracellular proteins" "RNA-mediated gene silencing" "Methyltransferase, RNA-binding, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 72.0" "Group enriched" "Detected in many" 4 "NK-cells: 58.7;Spermatocytes: 178.5;Spermatogonia: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "JURKAT: 71.4;MOLT-4: 68.2;NB-4: 75.3;U-937: 98.6" "Low region specificity" "Detected in many" "Region enriched" "Detected in single" 19 "cerebellum: 9.1" "HPA028464, HPA028497" Uncertain Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 32: U-937 - Innate immune response" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane, Focal adhesion sites" "HPA028464: AB_10600103, HPA028497: AB_10601552" "unprognostic (1.82e-1)" "prognostic favorable (2.56e-4)" "prognostic favorable (9.95e-4)" "unprognostic (2.92e-3)" "unprognostic (1.91e-1)" "unprognostic (3.88e-3)" "unprognostic (2.01e-2)" "unprognostic (1.49e-1)" "unprognostic (7.01e-2)" "unprognostic (1.25e-1)" "unprognostic (2.95e-1)" "unprognostic (1.19e-1)" "prognostic unfavorable (2.48e-5)" "unprognostic (2.53e-1)" "unprognostic (2.43e-1)" "unprognostic (2.18e-1)" "unprognostic (1.65e-1)" 5.4 2.9 8.6 8.0 8.9 13.3 8.0 6.8 9.2 8.5 4.9 6.5 5.0 3.9 4.7 2.7 2.3 6.5 1.8 8.9 9.6 3.4 2.0 4.7 13.5 8.0 8.1 5.2 2.1 0.9 5.3 5.6 8.9 3.7 9.5 3.0 3.0 3.4 3.2 3.8 7.6 3.6 7.8 11.1 4.7 72.0 10.6 18.7 2.2 6.2 11.3 6.2 2.0 8.6 16.9 8.5 0.7 0.0 0.7 0.5 0.1 4.0 1.5 9.4 1.5 24.7 26.0 0.0 8.9 7.5 0.0 0.1 0.0 0.2 5.9 5.5 0.0 42.4 31.7 0.0 8.1 25.4 36.4 7.8 0.5 2.1 0.0 0.0 1.9 71.4 0.0 18.5 0.4 42.8 68.2 75.3 24.0 13.5 3.7 29.3 0.0 1.5 0.0 18.0 40.1 0.0 35.3 9.8 0.1 2.4 0.0 55.7 0.5 0.0 31.4 17.5 0.1 11.2 15.0 0.1 0.0 98.6 0.3 43.3 19.7 43.2 61.8 24.0 55.6 12.6 30.0 56.4 24.6 7.1 24.7 45.1 19.6 55.6 29.8 19.5 31.2 39.9 8.6 8.9 6.8 9.2 8.9 9.6 8.0 8.1 8.9 7.8 10.6 8.6 2.4 0.0 1.1 2.3 5.4 1.7 1.4 6.6 1.2 5.2 8.1 7.1 1.8 14.3 4.0 5.5 0.0 12.8 28.0 4.0 3.9 3.0 12.2 2.2 3.6 3.0 4.9 13.9 5.2 1.3 21.5 5.2 2.6 2.4 7.0 2.9 6.1 0.5 15.8 0.0 3.7 4.0 4.1 11.7 3.3 20.1 5.0 7.5 1.8 3.7 11.2 3.6 58.7 4.0 2.7 2.8 7.4 3.0 8.0 1.2 5.5 0.8 2.8 2.4 6.6 3.0 3.5 178.5 107.7 2.9 1.6 5.2 23.0 8.5 6.1 3.3 HERC2 "D15F37S1, jdf2, p528" ENSG00000128731 "HECT and RLD domain containing E3 ubiquitin protein ligase 2" O95714 15 28111040-28322179 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEL: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017188, HPA048389, HPA074166" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 59: Non-specific - Translation" "Cluster 36: HEL - Hemostasis" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "CAB017188: , HPA048389: AB_2680382, HPA074166: " "unprognostic (1.59e-1)" "unprognostic (1.44e-1)" "unprognostic (1.92e-1)" "unprognostic (6.64e-2)" "unprognostic (6.62e-2)" "unprognostic (5.74e-2)" "unprognostic (9.17e-2)" "unprognostic (2.08e-1)" "unprognostic (1.87e-1)" "unprognostic (4.11e-2)" "unprognostic (9.40e-3)" "unprognostic (3.60e-2)" "prognostic favorable (1.41e-7)" "unprognostic (7.66e-2)" "unprognostic (2.10e-1)" "unprognostic (2.34e-2)" "unprognostic (1.71e-1)" 5.3 5.7 2.5 2.3 2.9 4.0 4.9 1.5 3.1 5.5 3.0 9.3 2.6 7.6 1.7 5.2 6.1 2.2 7.4 2.3 1.1 3.7 3.7 5.1 2.3 2.0 1.8 8.3 6.1 5.4 6.3 2.7 2.7 4.4 2.8 5.3 4.8 2.9 14.2 5.3 6.1 3.7 0.4 4.3 6.3 4.8 2.7 4.4 5.8 9.3 2.4 5.6 5.0 6.2 8.5 16.5 11.2 4.7 9.2 6.9 3.2 6.0 7.1 7.6 7.3 8.6 1.1 8.5 7.2 10.4 11.5 8.5 12.0 5.9 5.6 5.2 7.8 54.0 20.2 2.9 3.5 12.8 4.1 5.7 4.5 9.0 11.2 4.9 10.2 7.0 21.2 3.4 7.3 3.9 2.9 4.3 3.4 6.4 7.1 10.2 16.0 0.7 2.6 18.2 12.3 7.1 14.6 4.1 4.5 5.8 4.8 14.8 15.3 14.0 9.2 5.5 9.1 2.2 3.3 7.7 6.5 5.9 7.6 0.1 0.2 0.1 0.3 0.0 0.1 0.2 0.1 0.1 0.2 0.4 0.2 0.1 0.0 0.1 0.1 0.6 0.2 0.1 2.5 2.9 1.5 3.1 2.3 1.1 2.0 1.8 2.7 0.4 2.7 6.2 56.2 22.4 23.5 68.9 34.3 16.4 15.3 18.1 27.9 107.9 39.1 31.2 66.6 21.5 23.6 64.4 148.0 25.9 28.5 31.8 1.9 28.7 13.0 35.0 55.8 73.3 28.1 67.9 88.9 30.4 15.5 34.3 43.3 29.6 3.8 135.0 38.9 36.7 19.0 122.8 82.9 32.1 16.2 22.3 20.7 15.8 56.2 22.1 69.4 84.3 26.9 41.0 45.3 65.9 89.7 36.6 30.8 52.3 56.6 20.5 31.1 19.8 19.6 142.9 65.7 46.0 43.2 72.5 66.4 38.3 21.0 17.8 30.0 62.7 35.5 11.5 HERPUD1 "HERP, KIAA0025, Mif1, SUP" ENSG00000051108 "Homocysteine inducible ER protein with ubiquitin like domain 1" Q15011 16 56932142-56944864 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Unfolded protein response" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Plasma cells: 2680.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 497.6;U-266/70: 533.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037041, CAB037104, HPA040754, HPA041219" Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Cytosol" "CAB037041: AB_1840910, CAB037104: AB_1840912, HPA040754: AB_10794068, HPA041219: AB_10794268" "unprognostic (1.92e-1)" "unprognostic (3.47e-1)" "unprognostic (8.64e-2)" "unprognostic (3.93e-3)" "unprognostic (3.39e-1)" "unprognostic (5.00e-3)" "unprognostic (1.17e-1)" "unprognostic (9.69e-3)" "unprognostic (3.33e-1)" "unprognostic (2.56e-1)" "unprognostic (2.84e-1)" "unprognostic (3.50e-1)" "prognostic favorable (1.41e-9)" "unprognostic (1.06e-1)" "unprognostic (3.93e-2)" "unprognostic (2.19e-2)" "unprognostic (2.27e-3)" 75.3 108.4 68.4 102.0 70.6 113.6 128.9 73.7 92.6 127.1 99.0 149.5 98.2 65.7 220.2 53.2 86.5 77.8 92.0 67.9 77.9 193.1 193.0 92.0 114.1 77.3 72.8 188.8 377.0 206.9 78.8 97.1 75.2 213.0 141.8 39.7 170.0 102.0 102.9 58.7 84.9 77.8 78.4 114.8 144.1 25.0 74.6 58.0 213.6 120.9 246.6 94.5 45.0 82.8 28.6 30.9 29.8 61.8 66.9 86.9 105.2 65.9 104.6 83.5 64.9 43.1 63.5 115.0 82.7 64.6 84.6 47.9 51.0 23.3 82.4 67.1 30.8 9.9 48.3 156.3 364.6 21.1 49.5 106.0 219.2 38.0 119.6 100.4 64.4 125.9 15.9 159.6 236.3 24.1 39.8 42.7 19.1 164.8 68.9 27.0 74.9 497.6 179.8 31.8 32.7 37.5 57.5 278.8 308.2 41.9 31.3 77.4 40.0 34.8 34.4 30.8 26.8 533.9 191.0 182.6 49.3 28.7 46.4 224.0 291.2 139.5 113.2 238.1 124.0 383.2 120.1 149.7 230.6 340.4 77.2 117.8 215.9 179.6 175.0 915.5 263.8 417.7 68.4 70.6 73.7 92.6 67.9 77.9 77.3 72.8 75.2 78.4 74.6 82.8 316.4 70.5 105.9 16.6 964.5 364.0 561.8 316.3 203.7 134.6 191.3 185.2 221.5 91.5 193.4 71.7 281.5 131.9 577.3 369.1 170.2 192.7 73.3 162.5 121.3 199.8 434.4 40.8 29.9 197.7 182.4 223.8 251.8 260.5 151.8 108.8 134.2 164.0 194.7 47.1 32.2 569.7 290.9 241.6 395.9 251.6 104.1 507.7 948.0 88.1 197.0 94.3 81.4 21.1 30.7 144.8 336.5 95.5 2680.7 447.4 156.1 209.0 95.6 117.1 98.6 178.8 215.6 54.7 10.6 146.6 255.3 693.8 342.6 137.4 311.4 456.8 HFE "HFE1, HLA-H" ENSG00000010704 "Homeostatic iron regulator" Q30201 6 26087281-26098343 "Disease related genes, Human disease related genes, Predicted membrane proteins" "Ion transport, Iron transport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Kupffer cells: 25.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A549: 39.2;T-47d: 54.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017276, HPA053470" Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 6: T47d - Mammary gland" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Nucleoplasm "HPA017276: AB_1850677, HPA053470: AB_2682163" "unprognostic (6.96e-2)" "unprognostic (7.87e-2)" "unprognostic (1.73e-1)" "unprognostic (1.24e-2)" "unprognostic (6.07e-3)" "unprognostic (7.58e-2)" "unprognostic (4.23e-1)" "unprognostic (1.77e-1)" "unprognostic (8.21e-3)" "unprognostic (1.78e-1)" "unprognostic (3.31e-3)" "unprognostic (1.82e-1)" "unprognostic (1.33e-2)" "unprognostic (2.12e-2)" "unprognostic (1.38e-1)" "unprognostic (1.33e-1)" "unprognostic (3.17e-1)" 9.6 7.9 1.3 5.3 2.1 0.6 7.8 1.4 1.9 6.7 9.3 5.8 5.9 4.9 12.4 4.8 4.5 8.1 3.7 1.5 1.5 6.7 15.4 7.5 3.6 2.4 1.7 7.3 6.3 15.4 1.2 6.1 2.2 6.8 6.9 1.3 6.9 9.6 2.3 2.8 5.0 6.0 1.7 8.6 8.3 1.7 1.9 1.7 9.9 3.0 3.1 7.4 3.2 2.8 17.2 39.2 0.7 18.6 27.3 21.1 0.1 12.2 28.5 15.1 23.6 3.3 34.3 1.8 32.4 20.2 22.9 10.7 0.0 14.2 19.1 4.6 0.2 0.5 8.1 2.6 5.6 0.0 0.7 21.6 4.0 16.7 1.4 13.2 10.4 0.0 0.7 0.4 13.0 7.2 0.1 0.2 0.9 8.1 0.0 2.3 0.0 0.3 12.5 11.5 0.1 0.1 7.3 0.0 10.2 0.3 54.0 1.9 8.2 10.6 1.1 10.7 10.6 0.2 0.4 0.2 15.9 0.2 23.5 1.3 10.7 0.0 1.5 10.4 1.2 3.3 1.6 2.1 4.7 1.3 0.4 1.0 1.9 0.2 9.2 0.3 0.3 3.8 1.3 2.1 1.4 1.9 1.5 1.5 2.4 1.7 2.2 1.7 1.9 2.8 3.9 3.2 5.1 1.0 1.7 1.7 2.6 3.7 6.2 1.0 3.7 2.2 3.2 2.8 6.7 5.5 2.1 1.7 0.5 3.8 0.0 4.1 0.1 1.8 2.3 3.4 1.8 2.7 0.1 3.4 0.8 4.6 8.2 1.5 2.5 3.0 6.8 12.2 11.1 0.0 0.1 4.0 4.1 25.4 7.6 0.2 3.7 7.4 0.0 2.8 3.8 2.9 2.1 0.0 3.3 2.4 0.9 6.0 0.3 2.6 2.9 2.7 5.9 1.7 0.0 5.7 2.4 0.2 1.1 3.4 3.4 1.8 1.0 2.8 3.3 1.9 HLA-A ENSG00000206503 "Major histocompatibility complex, class I, A" P04439 6 29941260-29945884 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Adaptive immunity, Host-virus interaction, Immunity, Innate immunity" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Ductal cells: 3747.8;Proximal enterocytes: 5267.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "A-431: 1363.9;fHDF/TERT166: 360.3;HBEC3-KT: 366.7;RPMI-8226: 372.1;U-266/70: 344.6" CAB078470 Supported "Golgi apparatus,Plasma membrane" NA NA 170000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB078470: AB_10985125" "unprognostic (1.56e-2)" "unprognostic (9.14e-2)" "unprognostic (1.34e-2)" "prognostic favorable (9.59e-4)" "unprognostic (3.49e-1)" "unprognostic (1.21e-1)" "unprognostic (1.12e-1)" "unprognostic (7.28e-2)" "unprognostic (3.42e-2)" "prognostic favorable (6.47e-4)" "unprognostic (2.96e-1)" "unprognostic (3.24e-1)" "unprognostic (1.84e-2)" "unprognostic (1.01e-1)" "unprognostic (2.32e-2)" "unprognostic (1.20e-2)" "unprognostic (1.54e-2)" 635.4 714.2 15.0 34.8 15.5 137.7 566.7 14.7 36.5 504.9 18.0 737.5 278.3 476.1 181.1 366.8 390.3 239.9 473.4 14.6 17.0 687.0 392.0 1007.3 132.0 19.1 15.8 338.8 200.0 18.5 406.5 52.1 16.5 370.9 94.6 9.9 364.1 1.2 246.5 673.3 959.1 14.5 16.8 1413.1 442.2 132.6 18.0 138.9 531.9 14.5 178.3 412.3 466.8 18.3 1363.9 35.0 0.0 0.0 205.9 193.7 1.4 1.4 2.5 2.1 2.3 0.2 0.1 4.0 0.6 360.3 179.1 31.2 0.2 366.7 0.5 3.1 13.5 237.5 9.5 7.4 11.2 0.5 14.4 2.0 0.0 2.5 1.1 0.6 0.2 177.8 0.4 1.4 0.5 0.0 1.1 24.3 2.9 0.2 4.1 27.5 2.5 372.1 246.7 276.5 0.6 12.4 29.3 0.2 11.8 82.8 1.6 30.4 5.8 18.7 0.8 5.8 4.0 344.6 92.6 77.7 0.4 199.9 0.2 321.6 119.0 182.7 164.7 95.5 134.8 96.9 125.4 146.3 18.6 64.3 86.5 119.2 248.7 133.1 109.6 54.6 222.2 191.9 15.0 15.5 14.7 36.5 14.6 17.0 19.1 15.8 16.5 16.8 18.0 18.3 1622.4 371.8 478.6 22.9 1316.2 856.4 886.2 1417.5 228.8 30.8 289.6 188.5 147.4 936.5 952.5 503.9 6.2 18.3 1879.4 2631.8 88.0 3747.8 52.2 239.4 374.0 1717.8 955.2 499.4 3.6 1310.0 18.5 743.5 853.7 556.2 603.0 253.3 1266.2 276.4 1840.9 37.0 19.3 1755.3 1265.4 1575.0 1124.0 95.6 704.6 1419.1 635.0 67.5 3258.0 170.4 3201.9 49.3 16.1 1802.9 2452.4 484.1 1110.7 1026.6 5267.3 294.9 609.6 24.4 558.8 397.3 579.2 197.4 23.8 216.5 947.7 31.7 2234.9 1021.3 1225.4 1262.8 HMOX1 "bK286B10, HO-1" ENSG00000100292 "Heme oxygenase 1" P09601 22 35380361-35394214 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis Oxidoreductase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 4 "lymphoid tissue: 612.2" "Cell type enhanced" "Detected in many" "Endothelial cells: 327.1;Extravillous trophoblasts: 285.2;Hofbauer cells: 494.9;Kupffer cells: 954.1;Macrophages: 271.5;Syncytiotrophoblasts: 502.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 98.8;intermediate monocyte: 238.8;non-classical monocyte: 329.2" "Lineage enriched" "Detected in all" 7 "monocytes: 329.2" "Cell line enhanced" "Detected in many" "BEWO: 869.1;GAMG: 631.2;U-138 MG: 506.2;U-87 MG: 489.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000635, CAB017444" Enhanced Uncertain "Golgi apparatus,Plasma membrane" NA NA 170000 "Cluster 51: Monocytes - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 28: BEWO - Transcription regulation" "Cluster 4: Macrophages - Innate immune response" "Golgi apparatus, Plasma membrane" "CAB017444: AB_10617276, HPA000635: AB_1079089" "unprognostic (3.12e-1)" "unprognostic (1.00e-1)" "unprognostic (9.42e-2)" "unprognostic (6.94e-2)" "unprognostic (5.57e-2)" "unprognostic (2.47e-2)" "prognostic unfavorable (1.59e-4)" "unprognostic (7.56e-2)" "unprognostic (1.71e-1)" "unprognostic (4.91e-2)" "unprognostic (1.62e-1)" "unprognostic (2.76e-1)" "unprognostic (1.95e-3)" "unprognostic (1.91e-1)" "unprognostic (4.82e-2)" "unprognostic (2.26e-1)" "unprognostic (7.54e-2)" 150.2 48.9 40.9 64.6 48.8 99.3 20.6 42.4 66.3 28.2 46.4 35.2 106.0 10.4 7.6 48.4 40.7 52.6 18.2 40.6 46.6 96.2 136.5 113.6 57.2 52.3 46.5 139.0 41.7 7.4 9.6 72.2 56.3 6.7 31.1 1.7 15.1 4.0 107.1 74.1 64.5 38.7 45.9 612.2 19.9 17.8 60.7 25.1 11.3 21.4 49.4 46.2 29.2 56.2 12.2 179.1 1.8 37.7 170.9 49.6 869.1 83.2 57.6 42.9 48.6 82.1 11.3 0.1 18.3 83.3 631.2 10.1 11.4 1.9 16.1 308.6 9.2 4.3 51.5 179.3 218.9 11.5 54.8 146.3 4.2 282.3 19.7 74.6 130.9 0.5 0.0 87.4 152.5 6.9 0.2 4.3 18.1 130.4 20.7 1.2 15.6 28.4 35.2 104.5 2.7 2.4 215.8 19.1 15.5 92.5 8.9 3.0 44.3 506.2 22.1 82.5 82.5 53.5 77.0 9.3 489.4 5.7 8.6 11.3 98.8 7.7 1.1 238.8 0.4 24.8 0.7 1.7 44.6 2.9 0.1 0.5 47.1 5.3 329.2 1.1 1.8 70.9 40.9 48.8 42.4 66.3 40.6 46.6 52.3 46.5 56.3 45.9 60.7 56.2 19.3 3.2 19.0 0.0 11.5 16.4 27.5 11.0 10.8 0.0 25.0 9.1 2.9 24.3 10.5 5.5 0.0 50.5 3.5 59.1 21.5 13.6 2.1 39.6 12.9 327.1 16.0 5.7 0.2 1.5 285.2 64.1 9.2 74.6 11.4 98.4 23.6 23.6 494.9 0.0 0.4 8.3 18.3 954.1 175.8 4.1 31.1 271.5 35.6 1.9 184.7 0.4 9.2 0.5 1.4 8.3 26.1 5.3 2.5 110.6 61.5 157.9 7.1 0.6 0.0 40.8 52.7 0.9 4.4 5.5 15.6 502.0 6.8 6.9 6.1 118.3 HPS3 "BLOC2S1, SUTAL" ENSG00000163755 "HPS3 biogenesis of lysosomal organelles complex 2 subunit 1" Q969F9 3 149129638-149173732 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Albinism, Disease variant, Hermansky-Pudlak syndrome" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "GAMG: 115.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046281, HPA052778" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 34: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 57: B-cells - Immune response" "Golgi apparatus, Plasma membrane" "HPA046281: AB_10961641, HPA052778: AB_2681943" "unprognostic (1.47e-2)" "unprognostic (7.83e-2)" "unprognostic (1.04e-1)" "unprognostic (1.11e-3)" "unprognostic (1.28e-1)" "unprognostic (1.50e-1)" "prognostic unfavorable (6.04e-4)" "unprognostic (1.33e-1)" "unprognostic (1.75e-1)" "unprognostic (1.08e-1)" "unprognostic (1.82e-2)" "unprognostic (1.08e-1)" "prognostic unfavorable (4.38e-4)" "unprognostic (2.00e-1)" "unprognostic (1.28e-1)" "unprognostic (3.03e-1)" "unprognostic (3.06e-2)" 7.6 9.2 4.2 11.4 4.7 5.6 7.9 4.8 4.2 7.5 8.3 7.5 11.0 9.9 4.9 5.6 8.6 9.0 5.0 3.7 6.0 12.0 8.0 9.7 17.6 6.7 5.6 14.0 6.7 5.7 3.7 10.6 6.8 9.3 9.1 9.6 6.6 8.5 2.8 4.7 10.8 10.3 5.6 16.0 9.2 6.9 5.2 16.8 8.8 3.9 16.4 8.4 5.2 8.5 49.1 26.5 15.7 16.3 21.4 27.4 11.7 19.7 38.4 25.3 32.4 9.1 31.8 12.4 23.8 23.7 115.3 16.5 17.4 13.4 32.4 30.6 13.9 5.8 11.8 9.9 19.1 15.7 9.1 18.0 13.5 24.4 10.0 51.6 26.2 20.2 6.5 29.4 32.5 30.3 11.3 22.1 37.7 26.3 21.1 13.4 10.3 33.7 13.9 24.1 4.7 12.4 16.8 17.7 35.9 33.4 19.2 20.5 13.2 25.2 4.5 26.0 29.0 24.0 10.0 30.6 37.7 30.1 6.3 20.7 12.5 12.1 12.0 15.2 14.5 15.4 10.9 12.9 19.5 12.2 8.4 10.9 5.7 9.8 10.3 11.0 10.7 10.9 4.2 4.7 4.8 4.2 3.7 6.0 6.7 5.6 6.8 5.6 5.2 8.5 9.9 12.8 19.5 17.6 28.6 3.7 3.9 11.5 6.8 6.7 9.1 7.4 2.5 5.7 22.9 7.3 2.1 21.0 24.3 8.0 5.9 10.7 3.0 10.6 11.6 9.9 9.0 7.4 13.3 18.1 14.6 10.8 16.8 10.4 15.2 18.0 17.5 6.9 19.8 3.3 16.5 8.8 14.2 29.3 23.8 4.8 11.5 33.1 14.2 38.4 14.4 25.1 19.6 19.1 27.3 12.9 4.9 30.1 15.4 6.8 13.6 22.8 20.7 5.2 0.0 7.4 8.4 4.4 8.4 8.7 5.3 14.1 18.9 5.4 7.5 5.1 HRH1 ENSG00000196639 "Histamine receptor H1" P35367 3 11137093-11263557 "FDA approved drug targets, G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 46.1;Distal enterocytes: 44.9;Glandular and luminal cells: 41.6;Suprabasal keratinocytes: 41.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTEC/SVTERT24-B: 30.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029740 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 57: Non-specific - Angiogenesis" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA029740: AB_10601578" "unprognostic (4.60e-3)" "unprognostic (3.41e-2)" "unprognostic (6.37e-3)" "unprognostic (9.55e-2)" "unprognostic (3.32e-2)" "unprognostic (1.07e-2)" "unprognostic (9.60e-3)" "unprognostic (4.00e-3)" "unprognostic (7.54e-2)" "unprognostic (4.98e-2)" "prognostic unfavorable (1.27e-5)" "unprognostic (1.43e-1)" "unprognostic (1.70e-2)" "unprognostic (1.66e-1)" "unprognostic (3.13e-2)" "unprognostic (7.19e-2)" "unprognostic (1.20e-1)" 5.7 3.0 5.5 3.1 6.2 0.1 3.4 1.7 6.5 5.0 2.1 8.8 2.7 4.3 4.8 3.3 7.4 7.1 1.5 6.1 5.3 4.2 0.7 4.1 1.2 4.6 2.9 5.9 0.6 0.9 0.5 3.9 3.6 2.4 5.1 0.2 1.8 3.5 0.9 5.1 4.3 5.4 3.2 1.0 1.7 0.8 5.8 1.2 1.2 2.2 1.4 14.3 5.0 4.1 2.6 6.1 0.0 0.0 2.7 28.5 4.2 4.6 15.3 13.3 8.8 1.1 21.8 0.0 13.4 10.6 13.5 17.3 0.0 6.3 17.7 10.1 0.0 1.4 9.7 0.0 8.4 4.5 2.4 10.0 3.7 30.4 10.5 18.4 19.1 0.2 0.0 0.1 5.8 0.0 0.0 1.9 0.0 2.6 5.4 0.4 1.6 0.6 23.2 3.6 0.2 0.0 6.6 4.6 0.0 0.2 0.0 3.5 28.8 14.8 9.4 15.3 23.4 0.0 1.7 0.1 22.5 3.9 13.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.0 5.5 6.2 1.7 6.5 6.1 5.3 4.6 2.9 3.6 3.2 5.8 4.1 11.5 6.4 1.1 33.3 0.1 46.1 8.9 7.4 6.8 0.0 0.5 0.5 0.5 0.0 19.3 1.8 0.0 0.2 0.0 44.9 0.0 0.6 0.3 20.5 6.9 20.2 3.5 0.0 34.6 0.7 1.0 16.7 8.6 41.6 2.5 28.8 2.5 0.0 27.2 0.0 19.1 15.1 4.1 12.5 12.3 0.2 3.7 9.8 0.0 2.8 0.1 0.0 0.0 2.0 1.1 14.0 21.0 0.0 0.0 6.2 29.1 0.7 5.0 0.2 0.0 6.8 2.8 1.8 3.3 2.2 41.5 0.5 1.0 0.2 15.8 19.3 HSPB1 "CMT2F, Hs.76067, Hsp25, HSP27, HSP28" ENSG00000106211 "Heat shock protein family B (small) member 1" P04792 7 76302673-76304295 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Host-virus interaction, Stress response" Chaperone "Cancer-related genes, Charcot-Marie-Tooth disease, Disease variant, Neurodegeneration, Neuropathy" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 5909.6" "Cell type enhanced" "Detected in all" "Basal prostatic cells: 16589.4;Exocrine glandular cells: 6539.7;Squamous epithelial cells: 6300.1;Urothelial cells: 13091.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 2482.8;MCF7: 3979.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000497, CAB004439, CAB047330, CAB047331, CAB047332" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 19000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB004439: AB_627755, CAB047330: , CAB047331: , CAB047332: , HPA000497: AB_1851172" "unprognostic (2.55e-1)" "unprognostic (7.25e-3)" "prognostic unfavorable (9.94e-5)" "unprognostic (7.07e-3)" "unprognostic (3.47e-3)" "unprognostic (6.61e-3)" "unprognostic (4.08e-3)" "unprognostic (4.50e-2)" "unprognostic (1.27e-1)" "unprognostic (9.78e-2)" "unprognostic (8.70e-2)" "unprognostic (2.21e-1)" "unprognostic (5.72e-2)" "unprognostic (5.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.56e-1)" "unprognostic (3.63e-1)" 964.4 856.4 810.6 329.6 835.1 52.3 560.5 821.6 1798.8 2123.4 864.3 2043.6 208.7 2824.2 131.7 5909.6 993.8 217.2 2981.9 776.6 944.5 986.4 554.9 790.9 99.0 894.1 838.7 731.6 751.7 221.1 303.3 324.3 870.8 979.0 73.8 10.2 1075.3 522.5 3669.8 2258.3 523.8 1066.9 808.2 224.5 770.3 99.8 840.0 218.7 627.1 628.1 279.3 1579.4 3398.4 869.5 1251.1 902.4 79.5 576.8 487.3 447.5 5.1 514.9 249.8 260.9 325.8 84.8 660.7 8.5 389.1 599.1 514.1 1094.2 359.0 279.6 76.5 690.9 106.4 41.5 611.4 345.5 267.9 69.9 466.5 542.8 2482.8 370.0 50.5 436.6 831.3 169.5 459.4 1079.7 276.5 3979.7 117.1 508.9 407.4 212.7 800.6 417.3 195.8 974.5 342.8 423.2 7.6 529.1 363.8 1323.3 456.0 224.5 1674.9 551.6 504.2 778.8 1200.3 221.7 1310.1 85.7 145.9 10.7 575.9 247.2 579.5 19.7 13.6 10.9 58.8 78.2 28.1 115.0 92.4 62.1 31.5 105.5 102.1 88.2 5.8 79.7 112.8 56.5 64.5 46.7 810.6 835.1 821.6 1798.8 776.6 944.5 894.1 838.7 870.8 808.2 840.0 869.5 708.2 272.4 186.4 78.4 145.4 1849.8 16589.4 3603.0 1728.4 243.4 312.5 174.4 822.3 264.5 1899.4 1144.0 323.2 161.7 62.0 824.2 1500.7 2021.4 11.9 1181.8 1060.9 1038.7 422.0 136.1 4.3 6539.7 399.4 998.5 219.2 1227.1 216.7 136.3 725.7 234.7 1199.8 70.7 2.2 433.0 1245.1 147.7 2828.9 30.8 299.5 1024.8 2056.2 35.6 188.0 171.4 50.4 8.0 2.7 2719.4 1417.1 534.5 296.9 3854.8 95.3 2324.4 1253.9 29.2 611.4 551.2 2129.1 20.3 105.5 6300.1 2241.7 2432.7 758.2 68.2 390.5 13091.2 HTR1B "5-HT1B, 5-HT1DB, HTR1D2, S12" ENSG00000135312 "5-hydroxytryptamine receptor 1B" P28222 6 77460924-77463491 "FDA approved drug targets, G-protein coupled receptors, Predicted membrane proteins, Transporters" Behavior "G-protein coupled receptor, Receptor, Transducer" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 9.6;placenta: 6.7;stomach 1: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "pancreatic cancer: 0.7;stomach cancer: 0.8;testis cancer: 1.0" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 16 "HUVEC TERT2: 79.4;TIME: 35.1" "Region enriched" "Detected in all" 4 "basal ganglia: 38.6" "Region enhanced" "Detected in many" "basal ganglia: 11.7" HPA028808 Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Plasma membrane" "Endoplasmic reticulum" "HPA028808: AB_2672782" "unprognostic (3.86e-2)" "unprognostic (3.56e-1)" "unprognostic (7.68e-2)" "unprognostic (2.58e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-2)" "unprognostic (2.67e-1)" "unprognostic (2.11e-1)" "unprognostic (8.96e-2)" "unprognostic (4.03e-1)" "unprognostic (1.77e-2)" "unprognostic (1.24e-1)" "unprognostic (1.10e-3)" "unprognostic (3.08e-2)" "unprognostic (2.81e-2)" "unprognostic (1.34e-1)" "unprognostic (1.02e-1)" 0.8 0.6 2.1 0.4 6.0 0.0 0.2 0.0 3.8 0.8 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.5 0.0 1.2 2.1 0.5 0.0 0.4 0.0 0.6 4.3 0.3 0.1 0.0 0.2 6.7 1.2 0.2 0.1 0.3 0.2 0.5 0.1 0.2 0.1 0.1 0.1 0.0 5.0 0.5 9.6 0.0 0.2 0.3 0.0 1.3 0.5 1.4 0.0 0.4 0.0 0.0 0.0 0.1 0.0 0.4 3.5 1.7 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.2 0.6 2.2 1.4 79.4 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 35.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 6.0 0.0 3.8 1.2 2.1 0.6 4.3 1.2 0.1 9.6 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 HUNK ENSG00000142149 "Hormonally up-regulated Neu-associated kinase" P57058 21 31873020-32044633 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 9.8" "Cell type enriched" "Detected in many" 5 "Inhibitory neurons: 109.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 13.2;BEWO: 16.3;RH-30: 18.1;SCLC-21H: 14.8;SiHa: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA027295, HPA027372" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 29: Non-specific - Vesicular transport" "Cluster 28: BEWO - Transcription regulation" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA027295: AB_2672203, HPA027372: AB_2672239" "unprognostic (9.09e-3)" "unprognostic (7.29e-2)" "unprognostic (1.42e-1)" "unprognostic (5.95e-3)" "unprognostic (1.99e-1)" "unprognostic (2.12e-4)" "unprognostic (4.00e-2)" "unprognostic (6.90e-2)" "unprognostic (5.07e-1)" "unprognostic (2.27e-1)" "unprognostic (9.09e-2)" "unprognostic (1.13e-1)" "prognostic favorable (7.48e-5)" "unprognostic (8.84e-2)" "unprognostic (2.22e-1)" "unprognostic (1.39e-1)" "unprognostic (6.69e-2)" 0.7 1.0 0.8 1.3 1.3 0.2 1.2 0.4 4.7 0.4 0.0 3.6 1.4 4.1 1.9 0.4 1.9 0.5 0.4 4.2 2.6 3.7 0.5 0.9 0.4 0.4 0.1 0.6 9.8 0.1 1.1 4.6 0.1 0.9 3.7 3.0 0.6 2.1 0.3 3.0 2.7 2.4 0.0 0.1 1.3 0.9 0.2 0.7 0.6 0.2 0.6 1.5 0.7 1.6 0.0 3.9 13.2 0.1 0.0 0.0 16.3 1.3 0.0 0.2 0.0 5.3 0.1 0.0 0.5 6.2 0.2 0.0 7.7 0.0 0.1 0.1 3.9 0.0 3.7 2.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 4.7 0.0 0.0 0.0 1.1 0.2 1.1 10.2 0.1 0.1 0.1 18.1 0.1 1.3 0.0 14.8 9.8 13.2 1.0 0.5 9.3 5.5 1.4 0.0 0.1 9.3 0.1 0.0 0.1 0.0 1.8 0.0 0.0 6.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.4 4.7 4.2 2.6 0.4 0.1 0.1 0.0 0.2 1.6 0.2 6.4 9.1 7.5 0.0 5.1 2.6 0.2 0.6 8.1 0.5 2.8 3.5 14.3 3.0 7.3 2.1 9.2 0.0 4.6 0.0 5.3 0.2 1.2 1.3 0.8 4.9 0.0 19.0 3.3 13.9 7.9 0.5 3.4 0.0 4.3 0.4 1.0 2.7 3.3 109.6 5.1 0.0 0.0 4.2 0.1 0.3 0.4 3.6 1.0 0.1 8.1 0.0 10.1 1.5 1.6 4.4 0.0 0.0 2.1 1.8 1.9 0.8 1.2 0.0 6.3 2.2 0.7 1.1 0.7 5.8 6.2 0.5 0.0 10.6 0.9 HYDIN "CILD5, DKFZp434D0513, KIAA1864, PPP1R31" ENSG00000157423 "HYDIN axonemal central pair apparatus protein" Q4G0P3 16 70802084-71230722 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 9.9;choroid plexus: 23.9" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 52.1;Endometrial ciliated cells: 150.6;Excitatory neurons: 49.2;Respiratory ciliated cells: 153.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 1.8;RPTEC TERT1: 2.8;SiHa: 5.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA067155, HPA074129" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA067155: AB_2685792, HPA074129: AB_2686665" "unprognostic (8.90e-2)" "unprognostic (1.04e-2)" "unprognostic (8.65e-2)" "unprognostic (4.88e-4)" "unprognostic (4.25e-3)" "unprognostic (1.81e-1)" "unprognostic (3.87e-2)" "unprognostic (2.45e-1)" "unprognostic (3.95e-1)" "unprognostic (3.42e-1)" "unprognostic (4.90e-2)" "unprognostic (3.21e-1)" "unprognostic (2.52e-5)" "unprognostic (2.13e-3)" "unprognostic (1.02e-2)" "unprognostic (1.42e-1)" "unprognostic (3.97e-2)" 0.3 0.3 2.2 0.3 3.2 0.5 0.5 1.2 1.4 1.2 23.9 0.6 0.2 0.9 2.0 0.1 5.3 0.5 0.5 3.4 3.5 1.3 0.5 1.4 0.3 8.9 9.9 1.1 0.7 2.5 4.4 0.1 5.8 0.8 0.1 6.4 0.3 0.3 0.1 0.5 0.2 0.1 8.0 0.4 0.2 4.7 4.3 0.0 1.9 0.0 0.0 0.5 0.4 4.4 0.0 0.0 1.1 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.2 0.2 0.1 1.8 0.3 0.1 0.1 0.6 0.2 0.3 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.2 0.0 0.0 0.4 0.0 1.1 0.2 0.0 0.0 0.0 0.4 0.4 0.7 0.0 0.4 0.1 0.1 0.4 2.8 0.4 1.1 0.2 5.3 0.1 0.2 0.1 0.3 0.0 0.2 0.1 0.4 0.0 0.1 0.9 0.0 0.5 0.4 0.1 0.3 0.5 0.2 0.1 0.2 0.1 0.2 0.1 0.2 0.2 0.0 0.1 0.1 0.1 0.7 0.1 0.3 0.2 0.1 0.0 2.2 3.2 1.2 1.4 3.4 3.5 8.9 9.9 5.8 8.0 4.3 4.4 0.1 3.2 2.6 35.3 0.0 0.0 0.2 2.6 0.0 17.0 1.5 1.1 2.5 0.0 18.3 9.2 52.1 0.0 0.4 0.0 1.9 2.5 35.4 150.6 6.5 0.7 3.5 0.0 49.2 0.6 0.0 1.4 0.0 4.0 0.0 5.0 0.0 0.0 0.1 0.0 25.9 0.1 4.1 0.0 0.0 31.5 2.5 0.3 3.6 3.7 0.0 9.3 0.0 26.2 21.8 0.3 0.1 4.5 0.1 0.6 0.0 1.8 153.2 30.5 0.0 2.0 1.7 17.7 7.5 0.0 0.0 0.0 0.5 1.6 0.1 0.2 HYLS1 FLJ32915 ENSG00000198331 "HYLS1 centriolar and ciliogenesis associated" Q96M11 11 125883614-125900646 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cilium biogenesis/degradation" "Ciliopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 26.5" "Cell type enhanced" "Detected in many" "Early spermatids: 80.8;Late spermatids: 54.9;Spermatocytes: 92.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041210 Enhanced Supported "Plasma membrane,Cytosol" NA Yes "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 78: Testis - Spermatogenesis" "Cluster 6: T47d - Mammary gland" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA041210: AB_10794987" "unprognostic (2.46e-1)" "unprognostic (1.60e-1)" "unprognostic (1.49e-1)" "unprognostic (2.35e-1)" "unprognostic (3.53e-3)" "unprognostic (1.17e-2)" "prognostic unfavorable (1.92e-4)" "unprognostic (3.28e-1)" "unprognostic (1.04e-3)" "unprognostic (6.56e-3)" "unprognostic (7.63e-2)" "unprognostic (4.81e-3)" "unprognostic (3.00e-2)" "unprognostic (2.19e-1)" "unprognostic (2.49e-1)" "unprognostic (1.03e-1)" "unprognostic (4.56e-2)" 2.9 2.4 5.7 3.0 5.3 2.4 4.3 8.0 8.5 4.2 4.9 4.7 6.0 3.8 6.7 3.7 4.2 2.6 5.0 5.4 5.3 5.5 5.8 2.5 6.2 5.0 4.7 3.9 2.2 2.7 2.3 4.4 5.0 5.0 5.0 4.3 3.1 6.1 2.7 4.8 3.3 6.4 4.5 3.6 5.4 26.5 6.0 5.2 2.5 4.3 9.0 3.8 2.3 5.2 11.2 23.9 8.4 5.9 16.5 11.6 14.8 27.3 10.9 24.8 16.9 0.3 17.2 5.0 11.3 25.4 8.4 15.8 12.2 10.0 28.7 27.1 9.2 3.5 2.3 4.9 12.9 12.4 16.9 7.2 11.0 25.2 28.3 5.1 18.4 11.0 6.1 27.3 33.6 18.6 9.1 36.2 18.4 46.2 40.8 19.0 0.1 16.5 27.3 17.9 11.6 7.2 29.6 22.2 11.0 10.5 53.6 26.9 16.7 1.8 20.9 19.4 4.6 10.1 11.4 11.4 5.1 26.7 22.2 5.7 7.6 1.5 10.6 8.7 10.2 16.1 13.8 12.6 10.0 16.1 13.2 9.7 1.1 6.8 6.3 20.4 15.5 7.1 5.7 5.3 8.0 8.5 5.4 5.3 5.0 4.7 5.0 4.5 6.0 5.2 3.9 0.0 0.5 2.6 9.3 4.2 2.8 8.0 4.6 7.1 4.1 5.3 5.5 1.5 2.2 1.8 4.2 18.6 11.5 4.0 11.7 5.5 80.8 5.8 3.4 3.7 4.9 9.1 14.3 4.2 13.0 5.9 8.6 2.1 0.0 7.1 6.8 5.4 7.6 0.0 13.8 3.2 8.2 3.2 4.0 54.9 8.4 2.5 7.2 6.5 11.9 5.8 12.3 6.0 5.8 3.6 5.8 6.0 4.2 3.3 5.2 12.1 4.8 6.5 6.6 2.3 5.7 92.1 32.3 6.2 4.3 4.4 4.9 7.5 5.5 1.5 ICAM2 CD102 ENSG00000108622 "Intercellular adhesion molecule 2" P13598 17 64002594-64020634 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 168.1" "Cell type enhanced" "Detected in many" "Adipocytes: 341.8;Endothelial cells: 180.8;Hepatic stellate cells: 128.5;NK-cells: 106.1;Plasma cells: 114.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "HUVEC TERT2: 1260.8;TIME: 319.0" "Low region specificity" "Detected in all" HPA071155 Approved "Plasma membrane,Cytosol" NA NA 730000000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Cytosol "HPA071155: " "unprognostic (9.43e-3)" "unprognostic (3.31e-2)" "unprognostic (5.15e-2)" "unprognostic (1.15e-1)" "unprognostic (8.97e-2)" "unprognostic (1.64e-3)" "unprognostic (1.34e-1)" "unprognostic (3.74e-1)" "unprognostic (8.28e-2)" "unprognostic (2.15e-1)" "unprognostic (4.18e-2)" "unprognostic (1.55e-2)" "unprognostic (9.07e-2)" "unprognostic (1.48e-1)" "unprognostic (3.93e-2)" "unprognostic (6.04e-2)" "unprognostic (2.29e-1)" 97.4 11.3 39.6 30.4 39.6 20.7 78.7 40.3 48.3 20.3 34.6 26.3 14.1 24.4 6.7 12.1 22.2 18.8 99.7 38.2 40.5 44.3 14.6 84.5 60.5 42.1 40.9 12.7 15.4 9.0 12.4 79.3 42.9 16.1 18.2 1.2 16.0 8.6 37.9 16.3 34.2 29.5 41.4 168.1 18.8 3.5 44.6 31.5 33.6 55.9 41.8 33.0 21.4 40.6 0.0 0.0 0.0 0.0 11.3 10.8 3.2 1.1 0.7 0.3 1.1 2.7 52.2 92.9 16.6 0.0 0.3 0.4 1.2 0.0 1.7 22.3 0.0 82.9 4.4 10.0 1.8 14.2 0.3 0.4 0.0 0.8 0.2 0.0 1260.8 78.8 67.7 50.5 0.3 0.0 101.8 11.8 0.1 0.7 0.0 60.3 0.2 128.7 6.7 12.8 0.0 0.8 0.0 0.2 0.0 0.1 0.0 10.3 319.0 0.2 0.8 6.2 0.0 47.6 18.7 83.4 0.1 17.7 0.0 444.8 191.8 62.1 282.8 464.6 326.0 265.6 371.2 270.7 203.6 328.9 400.3 253.3 23.1 188.5 525.8 67.2 450.8 502.0 39.6 39.6 40.3 48.3 38.2 40.5 42.1 40.9 42.9 41.4 44.6 40.6 341.8 0.0 8.4 0.0 47.8 7.4 4.0 5.2 0.6 0.1 6.1 11.3 0.5 1.5 4.5 7.3 0.0 0.5 41.7 1.7 0.0 1.2 0.6 1.2 2.4 180.8 1.2 28.2 0.1 1.4 0.3 13.8 1.1 0.8 12.0 0.7 128.5 1.9 20.0 0.0 0.0 2.2 2.0 55.6 13.4 1.3 0.3 56.9 28.4 21.5 25.7 0.4 106.1 0.5 0.2 6.8 4.7 1.9 114.4 3.8 0.6 0.5 4.1 0.5 6.6 7.4 11.6 0.2 0.3 0.7 5.4 1.0 60.1 6.5 4.2 2.8 ICOS "AILIM, CD278" ENSG00000163600 "Inducible T cell costimulator" Q9Y6W8 2 203936763-203961577 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "bone marrow: 16.5;lymphoid tissue: 20.2" "Cell type enriched" "Detected in some" 12 "T-cells: 81.2" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "T-reg: 29.1" "Lineage enriched" "Detected in single" 54 "T-cells: 29.1" "Group enriched" "Detected in some" 8 "HEL: 4.6;MOLT-4: 12.1" "Not detected" "Not detected" "Not detected" "Not detected" "CAB032575, HPA034865" Approved Approved "Plasma membrane,Actin filaments" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" "Actin filaments" "CAB032575: AB_2122593, HPA034865: " "unprognostic (2.66e-2)" "unprognostic (2.13e-3)" "unprognostic (4.19e-4)" "unprognostic (2.35e-5)" "unprognostic (1.07e-1)" "prognostic favorable (1.80e-4)" "unprognostic (9.38e-2)" "unprognostic (2.89e-2)" "unprognostic (1.49e-2)" "unprognostic (3.51e-4)" "unprognostic (7.50e-2)" "unprognostic (2.12e-1)" "unprognostic (2.86e-5)" "unprognostic (7.05e-2)" "unprognostic (2.48e-2)" "unprognostic (1.93e-1)" "unprognostic (8.82e-3)" 0.5 0.1 0.0 7.7 0.0 16.5 0.3 0.0 0.0 0.2 0.0 0.7 0.7 0.2 0.1 0.5 0.3 1.4 0.2 0.0 0.0 0.2 0.4 2.6 14.3 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.5 1.3 0.0 0.4 0.0 0.0 0.2 2.3 0.4 0.0 3.3 1.3 0.2 0.0 20.2 0.4 0.0 16.2 2.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 12.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 4.2 0.0 15.1 6.8 0.0 0.0 15.7 7.2 0.1 0.5 0.0 0.0 29.1 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.3 0.0 3.1 2.9 0.0 0.0 0.0 0.0 1.0 1.5 0.2 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 0.0 0.1 0.2 0.1 0.5 0.0 0.0 0.0 0.0 0.0 1.1 2.0 0.2 6.3 0.0 0.4 0.1 0.1 0.0 0.0 0.2 0.0 0.8 4.7 0.1 0.0 3.1 3.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.7 0.0 0.3 0.0 1.8 0.1 81.2 0.0 0.0 0.1 ICOSLG "B7-H2, B7h, B7H2, B7RP-1, B7RP1, CD275, GL50, ICOS-L, ICOSL, KIAA0653" ENSG00000160223 "Inducible T cell costimulator ligand" O75144 21 44217014-44240966 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, B-cell activation, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 18.2;brain: 33.3" "Cell type enhanced" "Detected in many" "B-cells: 28.5;Glandular and luminal cells: 22.7;Langerhans cells: 39.0;monocytes: 21.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "naive B-cell: 2.4" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "Daudi: 19.9" "CAB026037, HPA029179, CAB079997" Approved Approved "Plasma membrane,Cytoplasmic bodies" NA NA 130000000 "Cluster 37: B-cells - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytoplasmic bodies" "CAB026037: , CAB079997: , HPA029179: AB_2732445" "unprognostic (3.03e-2)" "unprognostic (1.40e-4)" "unprognostic (3.52e-2)" "unprognostic (1.94e-2)" "unprognostic (6.74e-2)" "unprognostic (9.40e-2)" "unprognostic (6.94e-2)" "unprognostic (3.71e-1)" "unprognostic (1.40e-1)" "unprognostic (3.76e-2)" "unprognostic (1.40e-1)" "unprognostic (2.42e-1)" "unprognostic (3.00e-2)" "unprognostic (3.11e-1)" "unprognostic (1.36e-1)" "unprognostic (1.47e-1)" "unprognostic (1.84e-1)" 3.1 3.6 12.1 4.9 21.8 18.2 2.6 10.7 17.9 3.9 0.2 2.1 2.5 1.9 1.4 5.4 3.4 4.1 5.2 11.7 12.4 8.3 3.3 3.1 8.0 18.7 17.9 0.8 2.1 0.7 1.4 3.1 17.1 3.3 1.8 1.4 3.0 1.4 1.5 6.6 3.8 1.3 11.0 4.3 4.9 1.4 18.2 2.6 2.3 1.8 5.5 3.2 3.5 33.3 0.5 4.6 0.2 3.9 1.0 1.5 10.4 1.0 0.9 0.5 0.3 7.9 0.6 19.9 2.9 0.5 1.8 5.8 2.7 1.6 0.3 2.0 2.0 0.6 4.0 2.3 0.9 8.7 14.1 1.4 2.6 1.2 1.3 0.3 1.1 0.7 3.3 1.7 0.3 5.2 0.4 11.4 2.7 13.2 4.8 17.1 1.3 11.6 0.8 10.3 2.0 0.1 12.9 18.2 0.4 1.4 5.1 12.2 1.1 0.6 4.4 0.4 0.4 16.4 12.2 16.2 5.8 8.0 2.5 0.3 0.3 0.2 0.1 0.3 0.1 1.8 0.3 0.1 0.2 2.4 0.3 0.4 0.3 0.2 0.2 0.7 0.1 0.2 12.1 21.8 10.7 17.9 11.7 12.4 18.7 17.9 17.1 11.0 18.2 33.3 1.2 0.0 1.5 0.3 28.5 7.5 5.8 8.4 3.4 1.7 8.7 5.8 0.6 1.5 2.4 9.2 0.0 0.4 2.0 7.9 0.0 2.0 1.9 9.8 2.1 4.6 5.3 0.8 0.0 0.7 1.1 5.6 4.6 22.7 0.0 0.2 1.4 2.8 3.7 0.0 0.0 4.5 8.2 8.8 39.0 4.0 3.1 15.6 8.8 0.0 21.0 1.2 2.1 0.0 0.5 0.8 3.8 10.9 4.7 16.0 3.6 3.5 0.6 1.2 0.0 4.5 6.1 0.1 0.2 4.7 6.5 0.5 2.9 0.3 4.5 7.9 IFFO2 ENSG00000169991 "Intermediate filament family orphan 2" Q5TF58 1 18904280-18956676 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 43.0;skin 1: 169.9" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 121.0;Basal prostatic cells: 83.0;Suprabasal keratinocytes: 100.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "basophil: 12.6" "Lineage enriched" "Detected in single" 18 "granulocytes: 12.6" "Cell line enhanced" "Detected in many" "HDLM-2: 139.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015987, HPA064603" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 44: HDLM-2 - Immune response" "Cluster 22: Epithelial cell types - Mixed function" "Nucleoplasm, Plasma membrane" "HPA015987: AB_2121678, HPA064603: AB_2685296" "unprognostic (1.43e-1)" "unprognostic (1.06e-2)" "unprognostic (2.81e-2)" "unprognostic (1.18e-1)" "unprognostic (1.39e-1)" "unprognostic (2.08e-2)" "unprognostic (2.03e-2)" "unprognostic (1.78e-1)" "unprognostic (4.34e-2)" "unprognostic (2.27e-3)" "unprognostic (3.24e-3)" "unprognostic (7.42e-2)" "unprognostic (3.24e-2)" "unprognostic (5.24e-3)" "unprognostic (2.72e-1)" "unprognostic (4.71e-1)" "unprognostic (1.36e-1)" 5.3 9.2 7.4 8.2 6.6 10.4 12.6 19.6 10.6 12.3 0.6 9.0 2.0 7.4 2.4 43.0 5.2 7.0 4.2 6.4 7.9 6.8 5.8 7.5 8.6 11.2 9.3 3.3 19.1 10.7 6.5 7.2 9.7 9.4 2.8 4.3 14.4 9.1 7.9 169.9 3.9 7.1 6.8 6.3 4.4 1.8 9.6 6.2 6.4 4.2 14.0 8.5 21.6 8.8 23.3 37.2 9.9 27.4 6.2 4.9 16.0 17.2 11.4 9.2 6.4 51.5 26.6 0.3 21.6 13.1 10.6 57.6 7.6 36.6 7.4 139.3 6.7 0.4 7.1 20.4 4.5 4.0 21.3 3.2 36.3 12.4 15.7 15.2 19.9 1.2 1.4 4.6 6.1 4.9 3.9 3.7 4.2 23.9 8.8 13.1 6.1 9.8 5.4 14.9 31.6 1.7 13.1 18.2 12.6 10.1 4.9 2.1 54.6 12.4 17.2 7.3 50.5 9.7 11.3 0.8 8.3 5.7 14.8 12.6 0.2 0.0 0.4 0.3 0.5 0.5 0.3 0.4 0.1 0.2 0.3 0.6 0.0 0.2 0.0 0.4 0.3 0.1 7.4 6.6 19.6 10.6 6.4 7.9 11.2 9.3 9.7 6.8 9.6 8.8 4.1 3.2 5.4 5.5 6.0 121.0 83.0 24.1 40.5 6.8 11.5 13.5 6.8 12.8 9.7 1.8 0.0 5.1 20.9 4.9 1.9 17.3 1.3 23.3 5.9 7.7 2.4 3.2 8.5 17.6 5.4 4.7 3.1 10.2 3.8 0.8 4.6 3.4 2.4 25.2 9.6 1.3 2.0 1.6 17.1 4.5 1.2 6.8 14.2 1.0 3.5 4.4 8.2 11.6 8.8 14.6 3.3 3.0 15.5 15.0 0.8 9.3 23.1 1.8 0.0 3.5 7.5 0.8 0.4 32.4 100.3 4.0 13.9 0.4 1.3 44.2 IFRD1 "PC4, TIS7" ENSG00000006652 "Interferon related developmental regulator 1" O00458 7 112422887-112481017 "Predicted intracellular proteins, Predicted membrane proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 64.2;neutrophil: 112.3" "Lineage enriched" "Detected in all" 13 "granulocytes: 112.3" "Low cell line specificity" "Detected in all" "HPA024122, HPA072413" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 17: WM-115 - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA024122: AB_1851452, HPA072413: " "unprognostic (2.29e-1)" "unprognostic (3.47e-1)" "unprognostic (1.10e-1)" "unprognostic (9.82e-3)" "unprognostic (1.36e-2)" "unprognostic (2.39e-1)" "unprognostic (5.73e-3)" "unprognostic (1.37e-1)" "unprognostic (2.48e-2)" "prognostic favorable (5.45e-4)" "unprognostic (6.41e-2)" "unprognostic (2.93e-3)" "unprognostic (1.50e-3)" "unprognostic (4.81e-2)" "unprognostic (1.98e-1)" "unprognostic (2.89e-1)" "unprognostic (4.70e-2)" 35.2 24.6 11.2 6.5 14.4 57.7 32.3 13.2 16.2 23.0 31.7 30.3 8.1 20.8 4.8 24.0 25.4 4.6 30.9 13.9 19.0 21.3 27.3 40.1 3.9 11.0 13.2 31.3 102.9 9.8 31.2 7.9 13.0 28.1 5.5 13.4 25.7 6.4 58.9 21.9 22.2 10.2 11.7 19.9 38.3 24.5 13.1 4.5 25.6 3.1 3.9 24.1 25.8 19.6 22.1 26.8 25.9 21.7 44.4 28.2 25.0 23.8 26.6 36.0 29.6 42.7 21.1 12.2 52.9 18.8 64.6 15.0 21.5 29.2 46.9 17.1 31.7 13.8 46.1 37.9 61.5 19.9 9.5 24.7 43.4 39.7 47.1 18.9 18.3 22.2 46.5 17.4 14.2 35.7 24.1 20.1 51.8 26.9 30.1 24.6 9.2 22.9 6.0 6.1 37.9 18.9 28.0 15.5 61.2 57.7 9.8 15.2 12.6 45.8 10.4 35.0 68.5 27.2 34.8 37.1 12.9 43.6 63.8 19.8 7.6 64.2 7.2 6.5 6.2 8.7 7.7 7.9 6.6 7.2 6.8 7.0 112.3 8.0 6.4 4.6 8.6 5.2 11.2 14.4 13.2 16.2 13.9 19.0 11.0 13.2 13.0 11.7 13.1 19.6 179.3 32.1 31.4 39.2 110.6 197.3 159.3 55.6 259.6 50.3 141.7 142.6 60.6 37.1 55.0 18.4 89.6 66.5 130.9 276.0 17.6 49.6 43.9 123.2 159.7 96.8 138.2 24.6 36.1 56.5 84.2 135.5 162.6 190.1 74.4 51.3 52.8 21.7 126.1 21.9 24.4 183.5 54.9 96.9 153.4 10.1 36.7 141.8 103.2 44.0 55.8 32.4 20.6 24.1 42.6 55.1 287.8 41.0 104.6 143.9 226.9 13.3 34.1 86.8 39.5 138.9 172.7 25.5 14.5 135.1 126.0 151.7 129.8 53.4 180.0 154.4 IGFL2 UNQ645 ENSG00000204866 "IGF like family member 2" Q6UWQ7 19 46143106-46161299 "Predicted intracellular proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "skin 1: 41.6" "Cell type enhanced" "Detected in some" "Astrocytes: 17.9;Excitatory neurons: 27.1;Inhibitory neurons: 29.3;Oligodendrocytes: 38.5;Spermatocytes: 9.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 65 "CACO-2: 82.4;OE19: 166.9" HPA059137 Uncertain Approved "Nucleoplasm,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 61: Skin - Cornification" "Cluster 21: OE19 - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Nucleoplasm "Plasma membrane" "HPA059137: AB_2683920" "unprognostic (1.53e-1)" "unprognostic (7.87e-2)" "unprognostic (1.64e-1)" "unprognostic (1.69e-2)" "unprognostic (7.30e-2)" "unprognostic (9.74e-2)" "unprognostic (1.92e-1)" "unprognostic (1.81e-1)" "unprognostic (1.84e-1)" "unprognostic (1.68e-1)" "unprognostic (4.26e-3)" "unprognostic (9.63e-3)" "unprognostic (4.14e-9)" "unprognostic (1.27e-1)" "unprognostic (2.76e-2)" "unprognostic (8.73e-2)" "unprognostic (9.91e-3)" 2.4 0.0 0.2 0.0 0.2 0.0 2.0 0.0 0.8 0.1 0.0 0.5 0.0 0.2 0.5 1.5 0.1 0.0 0.2 0.2 0.4 0.0 0.0 0.3 2.0 0.7 0.3 0.0 0.0 1.5 0.3 0.9 0.8 0.0 0.8 0.4 1.0 0.0 0.0 41.6 0.1 0.2 0.2 0.0 0.0 4.1 0.3 1.0 0.0 0.0 0.0 0.0 0.7 2.1 0.0 1.7 0.5 0.5 0.0 0.0 0.4 0.0 0.0 0.0 0.0 82.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.0 0.3 0.0 0.0 1.6 0.2 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 166.9 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.8 0.2 0.4 0.7 0.3 0.8 0.2 0.3 2.1 0.0 0.0 0.0 17.9 0.0 2.2 0.0 1.1 0.0 1.7 2.0 1.5 0.6 0.0 0.7 0.0 0.0 4.3 0.0 0.7 0.0 0.0 8.7 0.0 0.0 0.2 0.0 0.0 27.1 0.2 0.2 0.8 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 29.3 0.4 0.0 0.0 0.3 5.4 0.0 0.0 1.8 0.0 0.0 0.2 0.0 6.0 38.5 0.0 0.2 0.0 0.0 0.0 0.6 0.1 0.0 1.9 0.0 0.0 0.7 9.8 8.7 0.0 4.7 2.6 0.2 0.0 1.4 0.0 IGFLR1 "FLJ22573, TMEM149, U2AF1L4" ENSG00000126246 "IGF like family receptor 1" Q9H665 19 35738801-35742453 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 49.9" "Cell type enhanced" "Detected in many" "dendritic cells: 29.9;granulocytes: 38.7;Langerhans cells: 33.7;Macrophages: 28.8;monocytes: 115.6;Plasma cells: 42.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "plasmacytoid DC: 899.7" "Lineage enriched" "Detected in all" 4 "dendritic cells: 899.7" "Cell line enhanced" "Detected in many" "HMC-1: 32.9;Karpas-707: 26.0;U-266/70: 34.0" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA012369, HPA070778" Uncertain Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Nucleoplasm, Plasma membrane" "HPA012369: AB_1858095, HPA070778: " "unprognostic (5.97e-3)" "prognostic favorable (6.55e-4)" "unprognostic (1.94e-1)" "unprognostic (5.42e-2)" "unprognostic (8.31e-3)" "unprognostic (2.34e-4)" "unprognostic (6.71e-2)" "unprognostic (1.74e-2)" "unprognostic (1.87e-2)" "prognostic favorable (1.59e-5)" "unprognostic (1.44e-3)" "unprognostic (3.52e-1)" "unprognostic (8.72e-12)" "unprognostic (2.74e-1)" "unprognostic (1.22e-1)" "unprognostic (2.29e-1)" "unprognostic (3.32e-3)" 7.6 10.9 6.1 19.5 6.8 14.4 6.2 6.0 9.3 4.9 6.0 6.5 6.1 3.4 5.5 4.0 6.4 6.1 4.5 5.9 11.1 14.0 49.9 11.3 33.0 9.1 6.8 4.4 9.3 1.4 5.5 4.5 7.4 6.2 6.4 4.6 7.8 1.5 4.5 4.4 13.2 4.4 5.6 28.6 7.9 6.7 7.1 12.6 7.2 2.1 23.2 7.3 3.5 7.5 2.2 10.0 3.5 8.3 1.1 1.7 2.0 1.5 1.1 1.8 4.7 3.0 2.4 4.0 3.2 0.7 0.6 1.6 2.0 2.1 0.9 3.3 5.0 15.0 3.4 9.1 2.8 1.7 32.9 2.7 1.3 3.5 0.8 0.6 1.9 7.7 4.9 26.0 0.5 7.4 5.1 16.7 1.6 9.4 2.7 6.0 3.3 8.3 1.7 3.2 2.4 4.5 3.4 2.4 1.8 1.3 3.4 7.8 0.5 4.2 2.0 2.6 4.0 34.0 7.5 2.8 4.9 5.8 3.0 147.9 190.9 184.1 94.2 167.7 106.6 169.3 107.3 88.8 253.2 172.1 95.8 77.0 208.6 144.9 125.3 899.7 136.3 139.5 6.1 6.8 6.0 9.3 5.9 11.1 9.1 6.8 7.4 5.6 7.1 7.5 0.3 0.0 13.5 2.6 24.5 0.6 0.3 0.0 0.0 0.4 1.3 1.3 1.2 1.5 5.0 0.0 0.0 0.6 29.9 1.2 1.9 1.9 0.0 0.8 0.6 0.8 3.0 6.1 0.3 4.2 1.8 0.9 1.1 0.7 38.7 0.6 2.2 20.3 14.6 0.0 0.4 1.8 0.0 15.7 33.7 0.6 0.0 28.8 5.4 1.9 115.6 2.7 12.3 2.5 1.0 1.4 0.3 0.0 42.1 0.2 0.9 10.8 3.6 0.4 0.0 1.0 0.9 0.4 0.5 1.9 0.9 0.3 20.8 0.4 2.4 0.0 IL10RA "CD210, CD210a, CDW210A, HIL-10R, IL10R" ENSG00000110324 "Interleukin 10 receptor subunit alpha" Q13651 11 117986370-118003037 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" Receptor "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 63.6;lymphoid tissue: 73.7" "Cell type enhanced" "Detected in many" "dendritic cells: 87.5;Extravillous trophoblasts: 93.0;Kupffer cells: 190.7;Langerhans cells: 145.0;Macrophages: 128.6;monocytes: 175.7;NK-cells: 110.2;Plasma cells: 129.5;T-cells: 105.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 30.5;HDLM-2: 76.6;Karpas-707: 27.7;RPMI-8226: 35.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA065647, HPA069086" Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Cytosol "HPA065647: , HPA069086: " "unprognostic (1.01e-2)" "unprognostic (2.07e-3)" "unprognostic (1.58e-2)" "unprognostic (7.08e-2)" "unprognostic (8.27e-2)" "prognostic favorable (4.47e-4)" "unprognostic (5.27e-2)" "unprognostic (4.84e-2)" "unprognostic (7.70e-3)" "unprognostic (5.94e-2)" "unprognostic (2.14e-2)" "unprognostic (3.83e-1)" "prognostic unfavorable (1.45e-5)" "unprognostic (1.82e-1)" "unprognostic (8.43e-3)" "unprognostic (2.19e-1)" "unprognostic (1.27e-1)" 13.9 8.9 4.7 39.8 4.9 63.6 6.1 4.4 7.0 5.6 4.9 12.0 8.0 3.5 2.7 6.4 5.2 17.9 5.3 4.2 5.9 4.1 13.1 23.8 51.7 6.9 5.1 3.1 2.4 2.6 3.6 14.2 5.5 4.7 14.5 0.5 5.2 3.2 1.7 3.2 24.8 10.4 6.0 73.7 9.2 1.9 5.3 16.9 4.2 3.3 32.4 20.7 3.7 7.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.5 0.2 0.0 0.7 0.0 0.5 0.0 0.0 76.6 0.0 0.2 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.6 5.6 27.7 0.0 0.0 0.4 6.0 0.1 0.0 0.0 0.0 0.0 35.5 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.1 0.0 2.2 0.0 0.0 0.0 0.1 0.0 5.6 1.0 8.0 0.0 11.4 0.0 3.3 48.9 2.4 52.8 68.6 38.3 12.6 51.0 62.1 44.7 6.2 17.9 33.3 3.4 70.2 58.6 17.3 88.7 84.1 4.7 4.9 4.4 7.0 4.2 5.9 6.9 5.1 5.5 6.0 5.3 7.5 2.2 6.4 16.0 0.3 52.8 5.7 0.4 0.0 5.7 0.1 1.0 1.9 2.7 0.0 1.3 0.0 0.0 1.3 87.5 0.5 0.0 0.2 0.1 0.4 0.5 4.9 0.0 9.3 0.8 0.8 93.0 2.3 6.6 0.7 12.6 0.0 3.6 1.4 60.4 0.0 1.2 0.0 0.0 190.7 145.0 0.5 0.3 128.6 17.8 22.5 175.7 0.4 110.2 0.0 0.6 0.1 0.1 0.0 129.5 0.0 0.0 1.0 1.5 0.1 0.0 1.6 2.7 0.1 0.3 1.2 4.1 3.3 105.5 0.0 0.7 0.4 IL13 "ALRH, BHR1, IL-13, MGC116786, MGC116788, MGC116789, P600" ENSG00000169194 "Interleukin 13" P35225 5 132656263-132661110 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted secreted proteins" Cytokine "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 19 "testis: 24.3" "Cell type enhanced" "Detected in some" "Early spermatids: 96.7;Late spermatids: 200.7;Spermatocytes: 44.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 187 "HDLM-2: 41.1" "Not detected" "Not detected" "Not detected" "Not detected" HPA042421 Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 40000 "Cluster 83: Testis - Spermatogenesis" "Cluster 44: HDLM-2 - Immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA042421: AB_10795504" "unprognostic (2.17e-1)" "unprognostic (2.29e-2)" "unprognostic (7.48e-2)" "unprognostic (2.18e-2)" "unprognostic (1.92e-1)" "unprognostic (5.21e-3)" "unprognostic (1.79e-1)" "unprognostic (2.69e-1)" "unprognostic (5.20e-1)" "unprognostic (7.10e-2)" "unprognostic (3.61e-3)" "unprognostic (3.34e-1)" "unprognostic (5.97e-4)" "unprognostic (4.70e-2)" "unprognostic (2.05e-1)" "unprognostic (7.39e-2)" "unprognostic (1.38e-1)" 0.3 0.0 0.1 0.6 0.0 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.2 0.1 0.1 0.1 0.0 0.0 0.3 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 24.3 0.0 0.6 0.0 0.0 0.0 0.5 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 41.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.1 0.1 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.2 0.3 0.9 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 96.7 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 17.7 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.4 200.7 2.8 0.1 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 1.0 0.5 44.4 1.2 0.0 0.6 0.0 14.7 0.0 0.0 0.0 IL17RB "CRL4, EVI27, IL17BR, IL17RH1" ENSG00000056736 "Interleukin 17 receptor B" Q9NRM6 3 53846568-53865794 "Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 28.9;kidney: 59.8;liver: 33.3" "Cell type enhanced" "Detected in many" "Astrocytes: 48.3;Enteroendocrine cells: 29.2;Oligodendrocyte precursor cells: 37.7;Proximal tubular cells: 78.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "basophil: 1.3" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "CACO-2: 20.2;Hep G2: 59.5;OE19: 46.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA005482 Enhanced Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 7: Kidney - Transmembrane transport" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Vesicles, Plasma membrane" "HPA005482: AB_1234567" "unprognostic (1.85e-3)" "unprognostic (4.22e-3)" "unprognostic (1.60e-3)" "unprognostic (2.86e-2)" "unprognostic (1.42e-2)" "unprognostic (6.20e-3)" "unprognostic (1.62e-2)" "unprognostic (6.09e-3)" "unprognostic (1.30e-1)" "unprognostic (5.41e-2)" "unprognostic (4.75e-2)" "unprognostic (4.27e-2)" "prognostic favorable (6.61e-4)" "unprognostic (8.10e-2)" "unprognostic (6.97e-2)" "unprognostic (5.29e-1)" "unprognostic (7.15e-3)" 0.9 2.0 20.2 2.3 21.4 0.5 5.7 22.7 28.9 18.1 16.6 6.8 5.8 5.1 0.7 1.7 3.3 2.4 2.7 19.4 20.2 59.8 33.3 3.8 2.5 18.7 19.9 1.5 7.8 1.1 4.2 0.9 19.0 2.4 6.9 4.8 4.9 0.6 1.3 2.2 5.9 0.8 18.9 1.2 3.6 2.5 23.2 0.3 2.9 0.2 0.7 0.8 1.3 23.6 1.5 3.1 4.5 3.4 0.1 0.0 7.1 3.1 0.1 0.1 0.0 20.2 1.4 4.6 1.0 1.0 1.7 0.8 12.2 0.0 0.0 1.6 3.5 6.0 6.1 59.5 0.0 5.6 3.2 0.0 0.0 0.0 0.0 3.8 0.0 1.6 4.9 2.1 0.1 4.2 0.9 2.3 12.1 46.2 2.6 1.7 1.9 5.3 1.4 5.3 6.4 3.7 10.1 2.4 1.9 3.3 9.2 2.0 2.5 3.0 3.3 2.6 3.9 4.7 5.6 2.9 2.7 3.3 1.7 1.3 0.2 0.0 0.2 0.2 0.1 0.1 0.6 0.2 0.0 0.2 0.2 0.2 0.1 0.1 0.0 0.3 0.9 0.1 20.2 21.4 22.7 28.9 19.4 20.2 18.7 19.9 19.0 18.9 23.2 23.6 0.2 0.0 4.1 48.3 0.2 0.3 2.0 0.0 0.0 0.1 8.2 4.4 4.1 17.2 1.3 0.0 0.0 1.4 0.3 4.3 9.8 4.8 1.0 0.5 1.0 0.2 29.2 0.0 0.5 1.6 1.0 0.6 4.6 1.7 2.5 0.4 0.4 13.1 0.1 0.0 2.5 8.7 2.0 0.0 1.1 0.7 1.2 1.2 0.0 1.9 0.0 4.4 0.0 37.7 4.3 1.8 3.0 0.4 0.0 4.4 2.9 78.0 0.0 0.1 0.0 0.3 0.5 0.4 1.0 0.0 0.1 0.4 0.9 0.0 10.2 0.6 IL21R CD360 ENSG00000103522 "Interleukin 21 receptor" Q9HBE5 16 27402174-27452042 "Cancer-related genes, CD markers, Disease related genes, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 7.6;lymphoid tissue: 24.7" "Cell type enhanced" "Detected in some" "B-cells: 15.5;dendritic cells: 21.8;Langerhans cells: 11.4;NK-cells: 23.7;Plasma cells: 13.4;T-cells: 25.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Daudi: 25.9;HDLM-2: 110.8;Karpas-707: 49.3;RH-30: 37.2;RPMI-8226: 63.0;U-266/70: 24.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA042296 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 3: T-cells - Adaptive immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA042296: AB_10806236" "unprognostic (2.91e-2)" "unprognostic (2.65e-3)" "unprognostic (6.64e-4)" "unprognostic (1.58e-3)" "unprognostic (2.14e-1)" "prognostic favorable (7.29e-4)" "unprognostic (8.33e-2)" "unprognostic (2.06e-1)" "unprognostic (8.50e-6)" "unprognostic (2.26e-2)" "unprognostic (1.13e-2)" "unprognostic (8.71e-2)" "unprognostic (2.34e-10)" "unprognostic (8.79e-2)" "unprognostic (4.42e-2)" "unprognostic (1.50e-1)" "unprognostic (9.58e-2)" 0.5 0.4 1.4 11.9 1.0 7.6 0.2 1.1 2.6 0.2 0.9 0.8 0.6 0.3 0.2 0.3 0.2 1.1 0.7 0.9 2.3 0.9 0.4 2.9 24.7 2.1 2.3 0.2 0.3 0.0 0.5 0.8 3.3 0.4 0.9 1.1 0.6 0.1 0.3 0.8 2.1 0.7 1.2 5.5 1.5 1.1 1.2 14.4 0.6 0.0 18.8 2.2 0.2 1.6 0.1 0.2 0.3 0.2 0.0 1.3 0.8 0.8 0.1 0.1 2.2 0.2 0.2 25.9 0.2 2.1 1.4 0.1 0.0 0.1 0.1 110.8 0.1 5.4 0.2 0.7 3.4 0.2 1.5 3.8 0.0 6.8 0.1 0.7 0.0 0.6 0.3 49.3 3.8 0.2 0.1 0.5 0.9 0.1 0.0 0.4 37.2 63.0 0.0 0.1 0.2 0.2 0.1 0.1 2.7 0.2 0.1 1.3 2.8 1.9 0.7 0.6 0.2 24.7 9.4 5.9 5.2 1.4 0.2 0.5 0.4 0.1 13.4 8.3 4.9 1.8 8.6 14.2 2.3 14.2 9.2 9.3 0.9 9.5 27.0 1.1 10.8 7.3 1.4 1.0 1.1 2.6 0.9 2.3 2.1 2.3 3.3 1.2 1.2 1.6 0.2 0.0 1.3 0.0 15.5 0.4 0.1 0.0 0.0 2.0 0.2 0.1 1.9 0.0 0.0 0.0 4.2 0.1 21.8 0.1 0.0 0.0 6.5 0.1 0.2 0.9 0.0 0.0 0.4 0.0 0.1 0.3 1.5 0.2 0.0 0.0 1.1 0.2 8.2 0.0 0.5 0.0 0.0 5.0 11.4 5.7 0.0 3.6 1.8 2.8 1.8 0.2 23.7 0.5 0.0 0.0 0.0 0.0 13.4 0.0 0.0 0.2 0.0 0.5 0.0 0.8 0.8 0.2 0.0 0.0 0.9 0.1 25.1 0.1 0.1 0.1 IL6ST "CD130, GP130, sGP130" ENSG00000134352 "Interleukin 6 signal transducer" P40189 5 55935095-55995022 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 580.3;Hepatic stellate cells: 808.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive CD4 T-cell: 16.7" "Lineage enriched" "Detected in many" 4 "T-cells: 16.7" "Cell line enhanced" "Detected in many" "ASC TERT1: 151.3;BJ hTERT+: 175.2;HHSteC: 155.1;HSkMC: 135.1;TIME: 147.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA010558, CAB025784" Approved Supported "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 160000000 "Cluster 32: T-cells - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Golgi apparatus" "CAB025784: , HPA010558: AB_1078439" "unprognostic (1.81e-2)" "unprognostic (1.25e-1)" "unprognostic (7.61e-2)" "unprognostic (3.95e-2)" "unprognostic (8.93e-2)" "unprognostic (3.99e-2)" "unprognostic (5.18e-2)" "unprognostic (9.53e-3)" "unprognostic (1.89e-2)" "unprognostic (2.29e-1)" "unprognostic (4.78e-2)" "unprognostic (1.59e-1)" "prognostic unfavorable (5.05e-4)" "unprognostic (3.69e-2)" "unprognostic (1.06e-1)" "unprognostic (1.80e-1)" "unprognostic (1.25e-1)" 67.1 46.0 26.8 14.1 31.0 9.6 51.3 30.9 36.7 43.0 21.3 33.9 4.2 35.2 18.5 18.4 34.2 23.6 35.1 23.5 31.4 30.0 77.6 53.3 15.9 32.1 27.0 36.9 21.9 39.6 22.5 101.7 35.9 32.6 14.3 28.6 31.9 29.9 41.0 17.8 31.1 28.7 35.1 34.7 27.8 8.9 25.3 23.6 40.4 34.7 16.2 37.7 35.1 42.9 14.4 35.6 9.4 18.8 75.5 151.3 22.3 54.5 175.2 44.1 62.4 40.5 16.3 1.1 33.7 52.5 71.6 7.8 9.8 19.2 84.1 1.6 8.5 4.6 20.1 14.2 155.1 0.4 6.2 135.1 11.1 103.1 42.7 43.6 101.8 1.9 3.7 51.0 47.0 2.9 0.7 0.8 1.5 1.8 10.1 1.1 22.5 14.4 22.5 12.1 3.8 5.9 26.6 5.7 19.7 13.7 29.5 3.1 147.8 12.4 10.1 44.5 24.6 14.6 8.2 0.5 28.9 1.1 31.1 0.0 3.9 0.1 0.7 3.4 0.3 0.8 3.7 0.8 2.1 0.4 16.7 4.8 0.6 0.8 0.5 1.9 4.1 4.0 26.8 31.0 30.9 36.7 23.5 31.4 32.1 27.0 35.9 35.1 25.3 42.9 221.6 134.6 149.8 59.4 30.0 103.9 98.0 60.6 71.2 56.5 202.4 81.3 81.5 124.4 105.4 68.0 35.5 77.9 33.1 34.5 7.9 85.3 12.3 76.4 227.6 256.2 19.8 41.1 25.7 62.0 75.5 285.5 59.1 580.3 32.9 58.6 808.5 219.8 56.0 16.8 70.0 34.1 46.8 93.7 99.1 16.7 105.9 60.3 80.0 188.3 45.8 190.8 7.2 75.4 64.2 80.8 35.6 130.5 100.6 163.9 33.6 52.2 80.3 39.3 98.6 158.7 150.3 54.4 38.6 44.9 83.5 101.8 75.5 228.7 17.1 106.1 INPP5A 5PTASE ENSG00000068383 "Inositol polyphosphate-5-phosphatase A" Q14642 10 132537787-132783480 "Enzymes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "basophil: 6.7" "Lineage enriched" "Detected in single" 28 "granulocytes: 6.7" "Low cell line specificity" "Detected in all" "Region enhanced" "Detected in all" "cerebellum: 250.8" "Low region specificity" "Detected in all" HPA012285 Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 80: Striated muscle - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 48: Smooth muscle cells - ECM organization" Cytosol "Plasma membrane" "HPA012285: AB_1851802" "prognostic unfavorable (7.47e-4)" "unprognostic (2.38e-1)" "unprognostic (2.54e-1)" "unprognostic (1.68e-3)" "unprognostic (1.43e-1)" "unprognostic (3.25e-2)" "unprognostic (2.08e-1)" "unprognostic (1.16e-1)" "unprognostic (5.65e-2)" "unprognostic (4.35e-1)" "unprognostic (4.70e-2)" "unprognostic (1.70e-2)" "prognostic favorable (3.15e-4)" "unprognostic (2.14e-1)" "unprognostic (1.44e-1)" "unprognostic (8.91e-3)" "unprognostic (8.66e-2)" 22.5 16.9 26.8 12.0 85.5 9.5 17.3 56.9 30.4 29.6 10.9 54.2 19.2 49.5 19.5 29.6 30.7 15.2 75.0 20.4 21.3 14.1 14.6 25.1 8.4 20.5 37.7 19.5 12.8 12.2 14.7 28.8 20.4 24.5 16.7 16.9 13.5 23.6 75.4 22.9 23.4 42.1 17.5 13.9 27.6 22.9 50.5 6.8 14.1 50.3 7.3 35.5 22.7 27.0 35.4 13.7 22.6 21.9 33.8 23.7 18.4 36.4 27.9 23.3 15.4 32.6 14.0 3.1 13.7 38.8 15.1 19.5 24.8 15.2 27.9 10.8 14.4 5.1 17.3 44.7 24.3 12.9 11.9 16.0 14.9 15.0 28.2 18.6 16.3 6.6 7.6 18.2 12.6 28.3 3.6 40.9 10.5 21.0 24.3 7.6 14.9 5.6 19.4 19.9 5.4 18.5 18.3 26.5 22.6 20.5 17.2 30.4 13.7 14.9 17.2 20.1 21.6 3.6 18.4 11.0 14.4 8.6 6.5 6.7 0.1 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.3 26.8 85.5 56.9 30.4 20.4 21.3 20.5 37.7 20.4 17.5 50.5 27.0 14.7 9.6 19.7 14.7 4.5 5.4 4.4 1.9 0.0 10.5 7.1 5.3 10.1 4.3 6.4 7.3 0.0 3.9 5.0 24.8 0.0 6.5 12.3 2.8 22.8 10.0 6.1 3.2 33.5 9.2 3.7 5.6 6.6 5.9 8.8 8.6 15.0 17.9 2.9 8.4 25.2 9.9 2.0 7.2 12.0 17.0 7.2 6.9 1.8 19.7 4.1 9.6 0.0 18.1 29.2 12.1 11.5 11.7 2.5 6.5 13.8 4.3 2.5 5.2 6.6 6.5 24.3 6.3 7.3 2.8 5.8 2.5 2.7 10.7 13.9 8.6 INSR CD220 ENSG00000171105 "Insulin receptor" P06213 19 7112255-7294414 "CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Carbohydrate metabolism" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Diabetes mellitus, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 8 "dendritic cells: 9.8;granulocytes: 5.9;monocytes: 12.5" "Cell line enhanced" "Detected in many" "Karpas-707: 54.9;U-266/70: 40.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036302, HPA036303" Uncertain Approved "Vesicles,Plasma membrane" NA Yes 190000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 2: Karpas-707 - Immune response" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA036302: AB_2675048, HPA036303: " "unprognostic (4.64e-2)" "unprognostic (2.42e-1)" "unprognostic (9.65e-3)" "unprognostic (9.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.15e-2)" "unprognostic (2.58e-1)" "unprognostic (5.09e-2)" "unprognostic (1.97e-1)" "unprognostic (3.05e-1)" "unprognostic (9.29e-2)" "unprognostic (1.86e-1)" "unprognostic (6.33e-2)" "unprognostic (3.45e-3)" "unprognostic (2.43e-1)" "unprognostic (2.75e-1)" "unprognostic (8.82e-2)" 13.0 22.6 12.5 2.8 16.8 5.6 13.0 17.3 12.8 14.6 18.8 15.0 10.0 18.4 6.3 4.1 16.9 8.2 26.3 10.0 12.2 21.8 33.0 7.2 2.3 18.3 16.3 39.9 64.2 13.0 16.3 7.4 18.7 15.2 10.4 6.5 16.9 9.9 23.5 11.5 12.2 11.5 14.1 48.2 12.5 5.4 16.6 2.7 14.5 13.3 3.5 12.3 9.2 22.5 6.2 3.2 3.6 5.7 18.8 6.1 11.1 3.5 2.9 1.6 1.6 8.4 7.0 9.0 8.2 6.8 4.0 1.6 8.9 1.4 1.2 0.0 6.4 0.0 2.3 22.6 8.2 4.3 6.7 10.0 4.5 0.2 4.9 4.2 3.8 4.8 9.5 54.9 1.8 3.2 3.1 7.8 3.3 3.8 5.2 29.0 2.1 7.6 0.1 27.8 6.6 5.2 6.5 3.8 3.3 6.4 1.4 21.6 3.6 3.4 2.1 8.2 5.1 40.4 23.9 20.2 4.3 7.3 0.0 2.7 8.6 5.9 0.2 8.8 0.3 0.8 0.3 0.1 9.8 1.1 0.7 0.1 1.9 1.0 12.5 8.2 0.0 1.6 12.5 16.8 17.3 12.8 10.0 12.2 18.3 16.3 18.7 14.1 16.6 22.5 75.6 48.1 34.7 64.9 10.6 64.9 63.6 34.7 8.0 40.4 134.0 76.2 92.1 137.2 83.3 62.5 79.2 17.8 6.7 124.1 15.6 55.1 4.7 26.8 106.8 123.9 163.6 25.0 68.3 78.7 53.7 43.7 20.4 42.1 3.8 168.4 255.2 246.0 9.2 38.7 100.8 97.3 32.6 49.0 31.1 9.0 96.3 35.0 51.6 62.8 24.2 31.6 0.0 62.8 183.5 50.7 68.8 245.3 21.8 107.9 122.9 114.1 65.3 23.6 59.2 37.6 44.2 5.2 3.6 3.2 68.8 38.3 4.7 81.4 65.2 130.0 IQGAP1 "HUMORFA01, KIAA0051, p195, SAR1" ENSG00000140575 "IQ motif containing GTPase activating protein 1" P46940 15 90388242-90502239 "Plasma proteins, Predicted intracellular proteins" "Host-virus interaction" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013302, HPA014055" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 1500000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cell Junctions" "CAB013302: AB_2533146, HPA014055: AB_1851856" "unprognostic (2.83e-1)" "unprognostic (7.73e-2)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (5.95e-2)" "unprognostic (4.24e-2)" "unprognostic (7.07e-2)" "unprognostic (1.17e-1)" "unprognostic (3.82e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.67e-5)" "unprognostic (2.01e-1)" "unprognostic (1.26e-1)" "unprognostic (2.02e-1)" "unprognostic (1.03e-2)" "unprognostic (1.87e-1)" "unprognostic (1.25e-3)" 57.3 31.1 14.4 69.3 30.0 69.7 51.6 19.8 20.5 62.0 26.9 67.1 32.3 72.2 21.3 75.6 45.1 55.0 22.9 17.0 21.5 35.6 18.8 74.2 58.9 29.0 24.6 39.6 30.1 49.7 12.1 79.8 28.1 36.2 66.9 7.1 72.2 38.0 15.0 64.9 37.9 81.3 16.5 57.7 52.6 13.0 27.9 65.4 64.3 25.4 63.4 63.5 31.4 63.4 148.9 81.5 39.8 46.6 99.3 128.4 229.6 139.7 127.0 124.7 132.4 93.6 150.5 82.7 66.2 231.5 111.4 259.2 80.6 153.5 149.5 106.4 56.6 55.5 145.8 34.3 120.2 102.9 113.6 76.2 139.5 147.2 206.5 152.7 172.8 53.0 49.0 112.8 192.3 76.5 55.4 30.8 51.6 235.8 45.6 67.5 106.5 72.1 126.9 233.8 49.5 37.3 195.1 96.9 100.7 162.8 85.1 86.5 224.2 141.1 73.4 120.4 145.6 43.3 67.0 82.4 128.3 98.5 77.5 30.6 27.5 20.0 21.8 25.2 19.3 12.6 13.5 18.9 23.3 12.5 7.9 14.0 89.9 27.6 31.0 13.8 16.1 16.9 14.4 30.0 19.8 20.5 17.0 21.5 29.0 24.6 28.1 16.5 27.9 63.4 180.9 266.0 286.3 36.2 129.2 103.0 124.9 87.7 72.8 4.6 115.1 88.4 18.0 54.3 167.2 77.3 16.7 89.7 215.3 204.5 7.9 95.9 8.8 133.8 127.9 135.7 60.7 46.7 39.7 98.7 159.4 116.5 91.7 242.0 209.3 130.2 95.3 11.6 149.0 1.7 24.4 121.1 63.1 407.5 175.1 13.2 47.8 261.6 71.2 60.9 272.2 13.5 200.8 9.5 316.0 128.1 112.1 48.2 137.3 98.6 72.7 19.6 134.2 30.2 78.9 108.8 131.0 18.9 32.6 99.3 113.4 95.6 176.8 56.0 152.0 151.5 IQGAP2 ENSG00000145703 "IQ motif containing GTPase activating protein 2" Q13576 5 76403285-76708132 "Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 113.1" "Cell type enhanced" "Detected in many" "Early spermatids: 1011.9;Late spermatids: 351.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "basophil: 21.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CACO-2: 74.2;Hep G2: 61.7;HMC-1: 211.8;RPMI-8226: 81.6;U-937: 57.0" "Region enhanced" "Detected in many" "hippocampal formation: 30.5" "Low region specificity" "Detected in all" "CAB004241, HPA037403, HPA037404" Uncertain Approved "Vesicles,Plasma membrane" NA NA 3700000 "Cluster 18: Basophils - Vesicular transport" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "CAB004241: AB_2125909, HPA037403: AB_2675459, HPA037404: AB_2675460" "unprognostic (9.46e-2)" "unprognostic (1.27e-1)" "unprognostic (1.35e-1)" "unprognostic (1.48e-1)" "unprognostic (9.03e-3)" "unprognostic (8.85e-2)" "prognostic favorable (5.65e-4)" "unprognostic (5.96e-2)" "unprognostic (1.14e-1)" "unprognostic (2.34e-1)" "unprognostic (2.14e-1)" "unprognostic (1.41e-1)" "prognostic favorable (9.44e-12)" "unprognostic (3.29e-2)" "unprognostic (9.89e-2)" "unprognostic (1.52e-2)" "unprognostic (1.27e-2)" 7.9 12.2 0.8 11.7 0.6 25.0 27.1 0.5 0.7 19.6 2.4 25.7 56.5 3.3 9.5 2.8 3.4 18.6 2.9 0.4 0.9 35.2 113.1 9.9 14.4 2.2 2.5 8.9 25.7 44.3 1.1 30.7 1.9 15.2 23.0 23.9 34.6 15.4 0.3 2.7 31.4 4.3 1.4 13.2 39.1 51.1 2.4 7.3 28.6 1.3 8.2 6.5 1.5 2.4 0.0 9.6 31.5 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 74.2 0.1 0.7 2.7 0.0 2.7 0.2 12.1 0.0 0.1 8.6 12.0 27.6 6.8 61.7 0.2 15.7 211.8 0.0 0.0 0.0 0.0 0.0 1.2 14.9 24.6 21.4 0.0 0.0 13.5 42.4 14.8 25.4 0.3 4.9 0.1 81.6 0.0 0.1 0.6 3.2 17.3 0.9 0.1 31.4 0.0 9.3 0.4 0.0 0.5 0.0 0.3 19.8 0.0 18.7 0.1 57.0 3.0 21.3 3.1 1.9 4.5 2.5 3.7 0.5 4.7 3.9 2.9 0.2 1.8 3.3 6.0 4.3 3.4 7.7 6.2 1.4 0.8 0.6 0.5 0.7 0.4 0.9 2.2 2.5 1.9 1.4 2.4 2.4 9.1 12.8 12.2 0.7 27.3 4.7 21.5 2.4 0.0 6.7 68.9 34.5 3.5 107.2 9.1 35.0 108.4 14.2 230.3 96.2 7.9 44.5 1011.9 43.8 3.3 7.7 9.1 76.3 2.3 66.7 1.2 22.0 99.4 37.5 94.9 8.7 18.5 235.7 65.9 1.7 19.0 52.9 61.1 132.6 63.3 351.0 7.5 141.3 16.0 47.8 63.4 14.0 114.4 0.5 1.1 18.7 37.5 5.3 148.3 21.5 87.1 65.2 16.1 121.8 0.0 3.9 3.5 25.5 11.4 1.2 3.8 7.3 112.1 82.7 43.7 6.5 IRAG2 "JAW1, LRMP" ENSG00000118308 "Inositol 1,4,5-triphosphate receptor associated 2" Q12912 12 25004342-25108334 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Fertilization, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 4 "bone marrow: 60.3;lymphoid tissue: 202.8" "Cell type enhanced" "Detected in some" "Adipocytes: 13.1;B-cells: 6.2;dendritic cells: 42.9;Hofbauer cells: 14.1;Plasma cells: 17.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 210.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 6 "Daudi: 634.3;REH: 221.9;U-698: 722.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA002967, HPA007356, HPA018505" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" NA NA 6700 "Cluster 45: Eosinophils - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Endoplasmic reticulum, Plasma membrane" "HPA002967: AB_1079161, HPA007356: , HPA018505: AB_1851988" "unprognostic (3.78e-2)" "unprognostic (2.59e-3)" "unprognostic (7.54e-2)" "unprognostic (7.08e-3)" "unprognostic (2.36e-1)" "unprognostic (1.48e-3)" "unprognostic (7.98e-2)" "unprognostic (4.08e-2)" "unprognostic (7.32e-2)" "unprognostic (1.15e-1)" "unprognostic (3.59e-2)" "unprognostic (7.97e-2)" "unprognostic (7.25e-3)" "unprognostic (7.72e-2)" "unprognostic (9.25e-2)" "unprognostic (1.31e-1)" "unprognostic (7.59e-2)" 9.6 1.9 8.5 47.2 5.4 60.3 6.5 2.3 5.6 2.4 3.2 10.1 8.7 2.5 2.8 5.2 5.1 7.8 2.4 6.6 2.6 9.4 6.2 7.7 171.7 6.0 4.4 5.7 30.7 1.5 2.4 4.4 6.1 3.4 9.2 1.1 3.6 4.4 1.1 5.8 19.1 4.5 3.6 37.5 10.1 1.0 2.8 95.1 4.9 1.6 202.8 14.5 8.3 4.6 0.3 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 634.3 0.3 0.0 0.0 0.2 0.0 2.4 0.0 22.1 0.0 37.8 0.0 0.1 0.0 49.7 54.2 0.0 0.0 0.7 0.0 0.1 0.0 31.5 7.8 40.6 0.0 0.0 54.5 91.2 0.1 0.0 0.0 221.9 0.3 63.8 0.7 29.7 0.2 0.1 0.2 0.3 0.2 0.1 0.0 36.7 0.5 0.0 1.5 0.0 0.1 40.4 7.8 722.4 0.2 21.8 0.0 80.2 21.0 210.1 23.6 40.8 20.2 66.1 14.9 24.2 22.4 51.0 25.5 25.4 151.3 49.0 51.5 20.8 2.7 20.2 8.5 5.4 2.3 5.6 6.6 2.6 6.0 4.4 6.1 3.6 2.8 4.6 13.1 0.0 0.0 0.0 6.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.2 42.9 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 3.9 0.0 0.0 0.0 ISLR HsT17563 ENSG00000129009 "Immunoglobulin superfamily containing leucine rich repeat" O14498 15 74173710-74176872 "Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 216.2" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 193.5;Fibroblasts: 154.5;Leydig cells: 214.9;Peritubular cells: 159.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 62.7;ASC TERT1: 33.5;fHDF/TERT166: 148.1;HSkMC: 25.5;RPMI-8226: 47.0" "Region enriched" "Detected in all" 5 "olfactory bulb: 118.0" "Region enriched" "Detected in all" 5 "spinal cord: 124.7" "HPA040326, HPA050811" Approved Approved "Golgi apparatus,Plasma membrane" "Secreted - unknown location" NA NA 130000000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" "Golgi apparatus" "HPA040326: AB_2676928, HPA050811: AB_2681243" "unprognostic (2.58e-1)" "unprognostic (1.36e-2)" "unprognostic (3.54e-2)" "unprognostic (3.06e-2)" "unprognostic (1.30e-1)" "unprognostic (1.76e-2)" "unprognostic (1.51e-1)" "unprognostic (1.21e-1)" "unprognostic (6.76e-3)" "unprognostic (1.16e-2)" "unprognostic (6.81e-2)" "unprognostic (8.93e-3)" "prognostic unfavorable (4.89e-8)" "unprognostic (1.64e-2)" "unprognostic (3.42e-2)" "unprognostic (2.28e-1)" "unprognostic (9.86e-3)" 89.3 17.5 4.4 5.5 11.8 0.0 66.9 1.7 10.4 216.2 5.4 75.1 5.7 181.4 18.9 17.1 78.7 38.6 63.3 4.6 5.2 20.9 8.2 37.7 9.9 2.8 3.2 170.9 10.1 2.1 44.6 10.2 2.8 51.4 5.2 0.3 33.6 22.9 18.5 46.7 31.3 26.3 2.3 33.0 32.5 14.9 4.5 3.3 63.4 19.7 5.3 63.5 111.9 5.0 0.0 1.5 0.1 0.0 62.7 33.5 0.2 10.2 0.1 0.0 0.0 0.0 4.0 0.0 0.6 148.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.7 0.0 0.0 25.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.1 0.2 0.2 0.0 0.0 0.0 0.0 47.0 0.0 0.0 0.5 5.8 0.0 0.0 0.0 0.6 0.0 0.1 0.0 0.3 0.4 7.6 0.1 0.1 1.1 0.0 0.3 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 11.8 1.7 10.4 4.6 5.2 2.8 3.2 2.8 2.3 4.5 5.0 10.3 0.0 1.3 0.7 0.1 11.7 0.1 0.2 0.0 0.1 4.8 3.9 3.9 1.5 0.7 0.0 0.0 1.3 0.8 0.0 0.0 0.2 2.4 7.2 193.5 14.0 0.0 0.0 1.9 0.2 1.4 154.5 2.0 4.2 0.0 0.0 7.5 0.0 3.8 0.0 0.2 0.0 0.0 0.0 16.2 6.1 214.9 2.6 12.4 34.7 0.0 0.2 0.0 0.5 0.7 0.8 0.0 159.9 0.0 0.1 0.0 0.1 1.5 0.5 26.3 7.0 49.8 0.7 0.7 1.3 8.8 1.0 2.6 7.0 0.0 0.2 ITGB2 "CD18, LFA-1, MAC-1, MFI7" ENSG00000160255 "Integrin subunit beta 2" P05107 21 44885953-44931989 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Integrin, Receptor" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 376.2;lymphoid tissue: 175.2" "Group enriched" "Detected in many" 6 "dendritic cells: 417.6;Hofbauer cells: 652.4;Kupffer cells: 485.9;Langerhans cells: 259.1;Macrophages: 527.4;monocytes: 463.8;NK-cells: 959.9;T-cells: 254.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 6 "THP-1: 812.4;U-937: 615.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008877, HPA016894" Enhanced Supported "Plasma membrane,Rods & Rings" NA NA 3300000 "Cluster 25: Monocytes - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Rods & Rings" "HPA008877: AB_1846256, HPA016894: AB_1846257" "unprognostic (1.94e-2)" "unprognostic (7.66e-3)" "unprognostic (1.23e-1)" "unprognostic (6.21e-3)" "unprognostic (2.95e-2)" "unprognostic (9.73e-3)" "unprognostic (2.53e-2)" "unprognostic (1.82e-1)" "unprognostic (1.18e-2)" "unprognostic (1.36e-1)" "unprognostic (1.20e-1)" "unprognostic (6.34e-2)" "unprognostic (1.87e-3)" "unprognostic (1.42e-1)" "unprognostic (4.42e-2)" "unprognostic (2.65e-2)" "unprognostic (4.83e-2)" 54.5 23.2 8.2 175.2 9.5 376.2 15.4 13.1 9.3 15.5 11.7 25.2 23.8 8.5 2.8 16.2 17.0 36.4 11.8 7.7 14.2 8.4 23.4 78.0 169.1 29.5 19.9 7.2 11.3 5.1 4.6 44.4 28.1 8.8 13.9 1.1 19.5 9.2 6.8 9.3 32.8 46.4 23.9 137.2 29.1 5.9 26.2 87.2 7.3 7.6 68.4 46.3 5.9 50.4 1.9 4.8 0.0 0.0 0.0 0.3 1.7 0.0 2.7 0.1 0.0 0.4 0.4 17.9 128.1 0.2 0.6 0.5 0.0 0.2 0.0 1.5 1.4 18.2 0.0 3.2 0.1 106.6 27.5 1.6 0.1 0.5 0.3 0.1 0.3 58.0 0.7 1.4 7.0 4.0 117.8 126.1 0.4 0.4 2.4 1.5 23.2 64.6 4.7 0.0 0.6 1.3 3.4 2.5 1.7 0.0 0.4 812.4 2.5 0.2 6.6 0.4 3.7 0.8 5.9 2.9 0.1 615.0 0.9 186.6 1848.8 1224.1 726.7 1144.9 326.6 86.1 349.7 506.5 1031.4 115.2 233.1 396.5 1386.1 585.5 1183.5 165.5 288.0 3034.2 8.2 9.5 13.1 9.3 7.7 14.2 29.5 19.9 28.1 23.9 26.2 50.4 7.1 16.0 29.6 0.3 81.7 5.5 0.5 9.6 0.6 0.0 4.1 6.5 4.0 14.3 18.6 5.5 0.0 4.0 417.6 0.3 0.0 3.4 1.0 0.6 0.5 16.8 0.0 19.6 0.5 0.4 4.8 5.3 2.6 0.7 24.1 8.2 9.7 8.6 652.4 0.0 0.3 0.2 2.0 485.9 259.1 2.8 0.6 527.4 5.4 27.2 463.8 0.4 959.9 0.0 0.2 0.6 0.1 1.5 50.5 0.6 1.8 4.2 3.6 0.8 6.6 2.1 3.2 0.2 1.0 0.9 5.1 5.6 254.5 0.0 0.3 0.7 ITGB3 "CD61, GP3A, GPIIIa" ENSG00000259207 "Integrin subunit beta 3" P05106 17 47253827-47313743 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 51.4" "Cell type enhanced" "Detected in some" "Early spermatids: 3.9;Late spermatids: 8.8;Macrophages: 15.8;Proximal tubular cells: 4.6;Sertoli cells: 6.6" "Group enriched" "Detected in many" 6 "melanoma: 7.5;renal cancer: 3.6;thyroid cancer: 11.5" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 19 "basophil: 5.4;neutrophil: 2.5" "Lineage enriched" "Detected in single" 26 "granulocytes: 5.4" "Cell line enhanced" "Detected in many" "EFO-21: 167.8;HEL: 163.4;RPTEC TERT1: 109.8;U-87 MG: 78.3;WM-115: 255.9" HPA027852 Approved Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 38000000 "Cluster 34: Basophils - Unknown function" "Cluster 1: Thyroid gland - Transcription" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" Nucleoplasm "HPA027852: AB_10601760" "unprognostic (1.13e-2)" "unprognostic (1.97e-3)" "unprognostic (2.47e-1)" "unprognostic (3.00e-2)" "unprognostic (1.91e-2)" "unprognostic (6.04e-3)" "unprognostic (3.70e-1)" "unprognostic (3.00e-1)" "unprognostic (1.44e-1)" "unprognostic (3.85e-1)" "unprognostic (6.35e-2)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.03e-2)" "unprognostic (2.72e-2)" "unprognostic (1.48e-1)" "unprognostic (1.17e-3)" 8.0 0.6 0.3 9.5 0.7 6.2 5.3 0.7 1.0 3.8 1.0 16.9 3.5 13.2 2.6 4.2 7.6 3.5 5.5 0.5 0.8 15.0 3.4 5.6 0.9 2.3 1.0 1.5 0.7 1.2 1.2 4.5 2.0 4.8 7.0 0.9 2.6 16.1 1.5 2.7 5.8 22.9 1.2 2.9 3.8 2.5 1.2 0.3 51.4 2.4 1.2 9.6 2.6 1.1 0.1 1.5 0.7 0.1 8.6 3.8 0.1 4.7 23.1 9.6 8.6 0.3 0.1 0.6 167.8 1.2 13.4 0.0 0.1 0.0 12.6 3.4 0.0 163.4 0.5 0.0 7.8 0.0 0.2 3.4 0.0 54.6 1.4 6.7 43.6 2.5 0.5 0.3 2.1 0.0 1.0 0.1 0.1 0.0 0.8 0.0 4.2 0.0 109.8 0.2 0.0 0.5 5.6 0.0 33.2 8.8 0.1 0.2 47.1 2.1 2.4 1.3 11.7 0.2 0.1 1.1 78.3 0.0 255.9 5.4 0.2 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 2.5 0.1 0.1 0.1 0.0 6.8 0.3 0.7 0.7 1.0 0.5 0.8 2.3 1.0 2.0 1.2 1.2 1.1 1.3 0.0 0.0 0.0 0.5 0.1 0.2 0.9 0.0 0.0 0.1 0.3 0.8 0.0 1.0 0.0 0.0 0.1 0.0 0.0 0.0 1.1 3.9 0.8 0.9 3.1 0.0 0.0 0.4 0.4 0.0 2.1 0.0 0.9 0.0 0.6 1.8 0.7 0.8 0.0 0.6 0.0 0.0 0.3 0.7 8.8 0.3 15.8 0.0 1.0 0.4 0.0 0.0 0.0 0.4 1.5 0.0 1.2 0.0 0.3 0.0 4.6 0.2 0.0 6.6 0.3 2.1 0.0 2.0 0.1 0.4 1.2 0.3 0.4 0.0 0.2 ITGB4 CD104 ENSG00000132470 "Integrin subunit beta 4" P16144 17 75721328-75757818 "Cancer-related genes, CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes, Disease variant, Epidermolysis bullosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 200.6;skin 1: 205.9" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 173.6;Distal enterocytes: 133.3;Gastric mucus-secreting cells: 165.1;Pancreatic endocrine cells: 284.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 897.3;HaCaT: 345.1;HBEC3-KT: 768.6;hTCEpi: 256.9;RT4: 254.9" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "spinal cord: 37.4" "CAB002422, CAB005258, HPA036348, HPA036349" Enhanced Supported "Plasma membrane,Cell Junctions" NA NA 980000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 27: Brain & Skin - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cell Junctions" "CAB002422: AB_563480, CAB005258: AB_2129021, HPA036348: AB_2675077, HPA036349: AB_2675078" "unprognostic (3.17e-3)" "unprognostic (3.52e-1)" "unprognostic (4.19e-1)" "unprognostic (2.27e-1)" "unprognostic (5.75e-2)" "unprognostic (6.11e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.18e-4)" "unprognostic (1.05e-1)" "unprognostic (4.14e-2)" "prognostic unfavorable (6.39e-4)" "unprognostic (1.02e-1)" "unprognostic (2.23e-2)" "unprognostic (1.65e-2)" "unprognostic (1.05e-1)" "unprognostic (1.07e-1)" "unprognostic (1.43e-1)" 39.2 5.3 82.8 12.4 87.8 1.6 66.6 74.9 91.8 58.4 76.4 87.5 56.9 24.0 3.6 101.2 43.8 20.0 22.7 80.5 86.9 18.2 5.6 18.4 4.5 104.6 104.8 8.5 24.5 2.8 21.1 35.4 82.6 85.3 15.7 8.7 200.6 18.5 6.8 205.9 75.5 6.4 102.4 76.9 79.9 4.9 82.0 4.1 17.6 6.0 7.2 58.4 98.8 99.6 172.7 148.5 0.3 2.1 0.4 1.3 199.2 0.7 0.6 0.5 0.9 16.1 897.3 0.1 31.5 0.3 1.3 345.1 1.0 768.6 0.5 0.7 0.6 0.9 39.6 17.0 1.2 0.2 1.8 1.1 256.9 0.6 159.2 18.0 5.5 0.6 0.5 15.7 0.1 95.8 2.0 2.0 1.0 92.8 127.8 2.7 4.4 2.2 204.8 254.9 0.2 1.9 4.9 15.2 2.2 5.3 63.9 1.5 16.9 4.6 7.8 0.7 1.9 5.6 2.1 0.7 2.0 0.8 2.7 0.0 0.2 0.0 0.4 0.4 1.1 0.7 0.1 0.5 0.0 2.0 0.4 0.3 0.7 0.0 0.0 4.6 0.8 0.4 82.8 87.8 74.9 91.8 80.5 86.9 104.6 104.8 82.6 102.4 82.0 99.6 26.9 12.8 2.2 50.3 1.4 49.5 45.1 173.6 67.2 0.3 21.2 36.6 7.5 25.8 38.9 23.9 2.1 89.8 1.8 133.3 1.9 33.3 0.4 61.3 5.7 26.8 9.6 0.8 0.7 28.8 20.2 5.2 165.1 60.2 2.5 1.1 17.9 0.4 9.4 0.0 0.7 59.2 18.3 0.3 5.4 0.4 3.7 1.9 12.4 1.9 0.1 34.4 0.0 1.5 0.7 284.4 68.4 1.5 2.6 17.1 94.0 2.6 53.3 1.0 0.0 1.2 5.0 1.1 8.2 28.1 13.1 111.1 1.8 0.5 60.1 42.0 ITGB5 ENSG00000082781 "Integrin subunit beta 5" P18084 3 124761948-124901418 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 459.9;hTERT-RPE1: 508.7;WM-115: 477.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001820, CAB022050" Approved Approved "Plasma membrane,Mitochondria" NA NA 64000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 17: WM-115 - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Mitochondria" "CAB022050: , HPA001820: AB_1079142" "unprognostic (2.63e-1)" "unprognostic (1.04e-1)" "unprognostic (3.57e-1)" "unprognostic (4.44e-2)" "unprognostic (1.37e-2)" "unprognostic (6.07e-2)" "unprognostic (3.49e-3)" "unprognostic (3.16e-3)" "unprognostic (1.68e-1)" "unprognostic (1.53e-2)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.16e-1)" "unprognostic (2.16e-3)" "unprognostic (2.49e-3)" "unprognostic (1.12e-1)" "unprognostic (1.01e-1)" "unprognostic (4.38e-3)" 102.7 32.5 24.4 26.0 33.4 3.3 71.3 32.6 20.3 84.7 71.0 48.1 33.1 75.9 16.4 54.9 33.2 71.7 68.8 24.6 28.7 48.6 51.4 53.9 6.0 38.2 32.9 28.0 23.1 21.8 20.5 82.3 35.4 37.3 24.9 14.3 49.6 46.9 30.0 88.9 32.5 60.1 32.3 41.0 29.7 13.5 32.5 12.2 34.3 33.7 9.9 40.3 70.0 35.8 189.1 459.9 32.4 82.7 296.6 84.2 166.3 197.5 120.0 35.9 57.6 92.6 240.3 0.8 93.5 336.3 177.0 148.0 29.5 102.7 31.2 2.0 20.1 66.3 69.5 98.0 51.0 0.4 116.8 51.2 23.2 91.1 46.9 508.7 121.2 0.2 60.7 98.1 122.7 190.0 0.8 1.1 145.8 105.1 50.4 0.4 52.2 71.8 98.8 41.2 0.9 67.5 146.6 214.5 165.7 56.4 121.9 4.2 318.2 134.9 200.7 118.5 103.7 16.6 18.4 1.3 141.3 0.8 477.0 0.3 0.2 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.1 0.1 0.1 0.3 0.1 0.0 0.0 2.5 24.4 33.4 32.6 20.3 24.6 28.7 38.2 32.9 35.4 32.3 32.5 35.8 50.4 6.4 6.7 55.5 1.0 17.2 23.1 18.8 6.2 8.1 20.6 27.2 28.9 42.9 10.0 29.5 4.2 68.5 0.6 34.9 11.7 38.3 10.7 22.0 21.4 27.5 3.5 2.7 0.9 18.8 7.4 52.1 11.2 13.4 0.0 135.9 31.1 39.1 72.3 35.3 18.1 12.9 2.0 36.8 17.5 4.1 20.2 28.5 10.6 60.9 0.4 50.2 0.0 16.6 12.5 70.4 27.0 16.6 0.6 24.9 21.0 10.7 6.2 14.9 39.5 31.3 52.1 2.6 7.0 15.6 22.3 55.1 1.7 1.0 16.3 14.8 ITGB7 ENSG00000139626 "Integrin subunit beta 7" P26010 12 53191323-53207282 "Cancer-related genes, FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Host cell receptor for virus entry, Integrin, Receptor" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 30.0" "Cell type enhanced" "Detected in many" "B-cells: 45.1;dendritic cells: 62.3;NK-cells: 134.9;Plasma cells: 115.9;T-cells: 62.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 99 "Karpas-707: 4821.4;RPMI-8226: 3980.8" "Low region specificity" "Detected in some" "Low region specificity" "Detected in some" HPA042277 Approved "Plasma membrane,Cytosol" NA NA 130000 "Cluster 52: Eosinophils - Transcription" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA042277: AB_10793877" "unprognostic (5.34e-2)" "unprognostic (4.47e-2)" "unprognostic (2.80e-3)" "unprognostic (1.40e-2)" "unprognostic (6.57e-4)" "unprognostic (3.51e-5)" "unprognostic (3.11e-3)" "unprognostic (1.37e-2)" "unprognostic (3.58e-1)" "unprognostic (2.18e-1)" "unprognostic (9.63e-3)" "unprognostic (3.36e-1)" "unprognostic (1.02e-2)" "unprognostic (2.16e-1)" "unprognostic (6.95e-2)" "unprognostic (9.34e-2)" "unprognostic (2.47e-4)" 1.6 1.4 1.7 20.0 1.8 15.5 1.9 1.7 2.2 2.7 2.0 9.7 11.7 1.6 2.8 6.4 2.9 3.9 0.8 1.5 2.0 4.7 5.3 6.6 29.2 2.3 1.8 0.7 1.2 0.7 1.3 0.5 2.0 1.7 9.5 1.0 4.1 2.3 0.7 11.9 17.3 2.4 1.9 30.0 8.2 0.6 2.8 8.6 3.1 0.6 26.5 6.2 2.9 2.1 0.1 0.0 0.0 0.3 0.1 0.7 1.4 0.5 0.0 0.0 0.5 0.0 2.1 44.5 0.8 0.0 0.0 9.4 0.0 0.3 0.0 16.5 0.0 1.5 0.0 0.0 0.0 1.0 18.5 1.0 1.8 0.2 0.1 0.6 0.0 2.2 0.4 4821.4 0.0 1.6 0.9 7.0 0.3 41.7 0.1 1.8 0.0 3980.8 0.0 1.2 1.9 0.6 0.1 1.8 0.5 0.0 0.8 10.4 0.0 0.3 0.6 0.9 0.0 8.9 17.9 3.8 3.8 2.6 1.6 80.7 5.6 97.7 52.0 1.4 38.2 28.1 51.8 63.0 44.5 29.8 44.5 44.4 1.5 23.7 0.4 11.9 71.8 17.3 1.7 1.8 1.7 2.2 1.5 2.0 2.3 1.8 2.0 1.9 2.8 2.1 1.0 3.2 5.5 1.3 45.1 2.2 0.3 1.7 3.4 0.1 1.3 1.0 0.5 2.8 1.3 7.3 4.2 0.1 62.3 0.6 7.9 0.3 0.0 1.2 0.4 0.9 0.0 2.1 0.0 0.5 0.1 1.3 2.6 2.4 29.2 0.1 0.4 2.2 13.3 0.0 0.1 0.5 0.0 3.7 10.3 0.3 0.0 17.3 7.2 1.9 13.3 7.0 134.9 0.0 0.5 0.9 1.7 0.0 115.9 0.2 0.0 7.6 0.2 0.8 0.0 1.0 8.2 0.2 1.4 3.3 3.7 0.1 62.5 0.1 1.2 1.4 ITGB8 ENSG00000105855 "Integrin subunit beta 8" P26012 7 20330702-20415754 "Cancer-related genes, Predicted membrane proteins" "Cell adhesion" "Integrin, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 53.9;choroid plexus: 39.4" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 376.2;Glandular and luminal cells: 551.9;Oligodendrocyte precursor cells: 192.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 133 "basophil: 16.5" "Lineage enriched" "Detected in single" 133 "granulocytes: 16.5" "Cell line enhanced" "Detected in many" "AF22: 44.3;EFO-21: 54.6;RPTEC TERT1: 88.1;WM-115: 127.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027796, HPA027797" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 17: WM-115 - Nervous system development" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA027796: AB_10600299, HPA027797: AB_10600879" "unprognostic (8.32e-3)" "unprognostic (1.42e-1)" "unprognostic (1.03e-1)" "unprognostic (3.37e-3)" "unprognostic (5.63e-2)" "unprognostic (3.53e-1)" "unprognostic (1.75e-1)" "unprognostic (1.46e-1)" "unprognostic (4.36e-2)" "unprognostic (1.75e-2)" "unprognostic (2.49e-3)" "unprognostic (8.47e-2)" "prognostic favorable (1.77e-4)" "unprognostic (2.90e-1)" "unprognostic (1.56e-1)" "unprognostic (4.63e-2)" "unprognostic (6.92e-3)" 3.8 2.6 25.7 4.2 41.8 0.3 9.6 53.9 19.2 15.4 39.4 3.7 3.2 7.7 14.0 6.4 7.5 8.7 2.9 19.5 37.5 21.6 0.8 2.4 0.5 38.9 48.4 4.7 13.3 5.1 5.4 5.2 42.7 6.7 2.8 4.6 13.6 9.0 0.2 6.3 4.2 3.0 39.7 0.0 4.2 6.5 35.6 0.8 2.1 0.9 6.9 7.2 9.0 48.6 28.2 1.1 44.3 5.6 3.7 15.2 0.0 0.1 0.5 0.2 1.5 0.3 6.9 0.0 54.6 2.0 1.7 30.1 1.9 4.5 0.5 0.0 0.7 0.0 23.1 0.0 1.8 0.0 0.1 1.8 12.6 0.5 2.4 27.1 2.4 0.0 0.0 8.3 0.8 0.1 0.0 0.0 3.3 0.4 4.8 0.0 3.7 0.0 88.1 2.5 0.7 1.9 8.6 0.2 23.5 0.8 0.7 0.1 3.0 11.2 7.1 3.2 5.8 10.2 0.1 0.0 2.7 0.0 127.0 16.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 25.7 41.8 53.9 19.2 19.5 37.5 38.9 48.4 42.7 39.7 35.6 48.6 0.7 12.8 4.8 106.4 2.5 33.1 117.2 39.4 34.7 13.3 26.3 18.7 3.0 38.6 57.9 38.6 0.0 20.0 0.4 5.0 7.9 26.3 3.0 376.2 150.6 5.2 34.0 0.0 28.1 17.4 1.2 15.5 7.7 551.9 1.3 0.9 1.4 0.2 3.3 1.7 8.2 7.4 34.6 1.0 4.7 6.5 44.1 9.8 3.6 4.7 31.6 24.3 0.0 192.0 119.2 35.8 6.1 44.8 2.0 149.7 14.5 76.7 100.1 1.4 0.0 4.8 7.0 1.4 1.1 34.6 12.4 4.9 5.5 1.9 9.6 150.7 ITK "EMT, LYK, PSCTK2" ENSG00000113263 "IL2 inducible T cell kinase" Q08881 5 157142933-157255185 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Adaptive immunity, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "lymphoid tissue: 57.9" "Group enriched" "Detected in some" 6 "dendritic cells: 51.7;granulocytes: 31.8;NK-cells: 42.2;Plasma cells: 34.0;T-cells: 115.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Group enriched" "Detected in many" 23 "gdT-cell: 39.6;MAIT T-cell: 26.4;memory CD4 T-cell: 55.6;memory CD8 T-cell: 54.9;naive CD4 T-cell: 78.2;naive CD8 T-cell: 65.0;NK-cell: 29.3;T-reg: 73.2" "Group enriched" "Detected in many" 23 "NK-cells: 29.3;T-cells: 78.2" "Group enriched" "Detected in some" 10 "JURKAT: 62.2;MOLT-4: 23.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA043670 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA043670: " "unprognostic (2.08e-3)" "unprognostic (6.57e-4)" "unprognostic (5.06e-3)" "unprognostic (4.96e-5)" "unprognostic (1.52e-2)" "unprognostic (1.12e-4)" "unprognostic (8.45e-4)" "unprognostic (1.56e-2)" "unprognostic (1.87e-2)" "unprognostic (5.99e-3)" "unprognostic (1.76e-1)" "unprognostic (2.52e-1)" "unprognostic (4.52e-6)" "unprognostic (3.64e-1)" "unprognostic (4.42e-2)" "unprognostic (1.46e-1)" "unprognostic (3.26e-2)" 1.0 0.3 0.0 15.9 0.0 3.7 0.9 0.0 0.0 1.0 0.0 1.4 0.7 0.4 0.0 1.4 0.4 4.2 0.2 0.0 0.0 0.3 1.6 3.1 29.3 0.0 0.0 0.1 0.2 0.0 0.0 0.2 0.0 0.4 1.5 0.0 0.3 0.1 0.0 0.2 4.0 0.5 0.0 10.5 3.1 0.5 0.0 57.9 0.5 0.0 24.6 3.9 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 3.9 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 0.0 0.0 62.2 0.0 0.0 0.0 0.0 23.7 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.1 0.0 39.6 0.0 26.4 0.0 55.6 54.9 0.1 0.0 78.2 65.0 1.3 29.3 2.3 0.1 73.2 44.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 6.2 0.0 4.0 2.7 0.6 0.0 0.0 0.0 0.4 0.4 0.9 0.0 0.6 1.8 0.0 0.1 51.7 0.1 0.0 0.1 8.5 0.2 0.3 0.8 0.0 1.7 0.2 0.0 0.0 1.1 7.7 0.4 31.8 0.1 1.8 1.0 0.0 0.0 0.2 0.0 0.0 1.6 5.1 6.7 0.0 2.9 1.8 1.0 2.8 0.0 42.2 0.0 0.1 0.0 0.0 0.0 34.0 0.3 0.0 0.4 0.0 0.0 0.0 1.0 1.0 0.0 0.0 0.2 3.4 0.1 115.7 0.0 0.1 0.6 ITPKA "IP3-3KA, IP3KA" ENSG00000137825 "Inositol-trisphosphate 3-kinase A" P23677 15 41493393-41503551 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 36.5;intestine: 18.1" "Cell type enhanced" "Detected in some" "Distal enterocytes: 51.4;Early spermatids: 45.4;Gastric mucus-secreting cells: 34.1;Late spermatids: 166.4;Proximal enterocytes: 35.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "MAIT T-cell: 1.4" "Lineage enriched" "Detected in single" 11 "T-cells: 1.4" "Cell line enhanced" "Detected in many" "Hep G2: 33.6;OE19: 18.2" "Low region specificity" "Detected in all" HPA040454 Enhanced Approved Approved "Vesicles,Plasma membrane" No No "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 31: Spermatids - Spermatogenesis" Vesicles "Plasma membrane" "HPA040454: AB_10672897" "unprognostic (5.91e-2)" "unprognostic (2.16e-3)" "unprognostic (4.19e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.77e-4)" "unprognostic (2.25e-2)" "unprognostic (2.69e-2)" "unprognostic (1.01e-1)" "unprognostic (3.58e-1)" "unprognostic (1.28e-1)" "unprognostic (1.21e-1)" "unprognostic (2.06e-1)" "prognostic unfavorable (3.76e-9)" "unprognostic (2.15e-1)" "unprognostic (2.87e-1)" "unprognostic (1.12e-3)" "unprognostic (2.10e-2)" 0.2 7.3 21.4 0.7 26.7 0.4 0.2 13.8 36.5 1.3 10.9 10.7 17.6 0.3 0.1 0.3 0.5 0.2 2.6 28.7 12.4 0.2 1.7 0.5 0.1 10.9 12.0 0.3 1.9 2.0 0.4 0.3 11.6 0.8 2.7 0.3 1.4 0.3 4.4 0.4 18.1 0.3 11.3 0.2 10.9 10.4 12.1 0.0 0.2 0.0 0.0 0.6 0.9 20.4 7.1 1.9 0.3 7.9 0.0 2.5 14.3 4.3 3.4 2.8 2.9 16.3 0.3 0.0 3.5 0.4 6.3 0.8 3.4 0.3 0.2 6.6 4.3 9.9 4.7 33.6 12.6 3.4 0.5 0.2 0.2 2.7 0.8 1.6 0.2 1.3 12.9 1.9 1.0 4.7 0.3 6.5 0.9 18.2 5.6 1.7 1.4 0.6 0.3 0.4 0.7 1.5 3.2 0.0 0.3 0.0 0.9 5.0 0.3 6.9 7.1 7.7 11.8 1.0 10.8 0.0 12.6 13.2 2.3 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 21.4 26.7 13.8 36.5 28.7 12.4 10.9 12.0 11.6 11.3 12.1 20.4 0.1 0.0 0.0 3.3 0.5 0.1 0.3 0.1 0.0 0.0 0.3 0.0 1.4 0.0 0.1 0.0 0.0 0.6 0.1 51.4 0.0 0.1 45.4 0.3 2.4 0.5 0.0 0.8 23.7 0.7 0.5 0.3 34.1 0.3 0.0 1.0 0.4 0.3 0.2 0.0 0.8 12.0 0.0 0.0 0.0 166.4 2.5 0.4 0.0 1.9 0.0 7.9 0.0 1.5 2.9 0.8 16.1 1.5 0.1 0.1 35.8 0.1 0.1 0.2 6.6 0.3 0.5 14.4 4.9 0.0 0.0 0.1 0.4 0.1 18.7 0.2 ITSN2 "KIAA1256, PRO2015, SH3D1B, SH3P18, SWA, SWAP" ENSG00000198399 "Intersectin 2" Q9NZM3 2 24202864-24360536 "Predicted intracellular proteins" "Differentiation, Endocytosis, Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036475 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 36: HEL - Hemostasis" "Cluster 10: Non-specific - Unknown function" "Vesicles, Plasma membrane" "HPA036475: AB_10670718" "unprognostic (2.36e-1)" "unprognostic (1.28e-1)" "unprognostic (1.24e-1)" "unprognostic (5.95e-2)" "unprognostic (4.64e-1)" "prognostic favorable (2.98e-4)" "unprognostic (3.32e-2)" "unprognostic (3.83e-2)" "unprognostic (2.77e-1)" "unprognostic (1.66e-1)" "unprognostic (2.69e-2)" "unprognostic (1.02e-1)" "unprognostic (1.66e-1)" "unprognostic (2.39e-1)" "unprognostic (2.72e-2)" "unprognostic (2.41e-2)" "unprognostic (2.12e-2)" 23.1 21.4 11.0 35.8 11.1 73.6 15.3 6.6 12.3 22.1 17.5 19.5 17.6 19.5 12.9 36.7 15.4 19.0 20.0 10.3 10.3 21.2 27.4 27.0 53.3 12.1 12.5 16.4 67.0 18.7 16.2 24.7 11.8 17.8 20.1 16.0 18.4 15.0 23.3 26.5 22.4 18.0 9.4 43.3 24.7 15.2 15.3 30.0 50.7 18.9 50.9 22.2 24.5 15.7 41.2 19.7 4.8 14.2 13.6 18.1 43.5 24.5 22.8 11.1 13.2 19.2 21.4 63.6 21.2 20.4 32.7 18.2 21.9 15.5 18.3 50.8 21.0 86.1 12.6 21.4 22.9 44.7 47.6 14.2 17.7 19.4 33.7 21.1 35.3 23.7 25.0 46.7 17.6 16.9 18.4 21.7 8.9 24.9 19.1 22.8 55.7 19.0 19.6 76.0 3.3 9.9 19.4 20.6 29.5 19.2 14.1 23.7 49.1 23.6 20.6 19.6 22.9 50.6 60.4 65.0 18.8 40.4 21.0 69.6 30.4 56.2 31.1 37.0 32.8 68.7 26.8 27.7 28.7 73.1 27.4 24.6 112.8 26.5 59.3 18.9 31.2 20.3 11.0 11.1 6.6 12.3 10.3 10.3 12.1 12.5 11.8 9.4 15.3 15.7 62.6 96.1 103.3 64.6 143.2 51.7 82.0 21.7 41.5 23.7 21.9 20.2 70.5 22.8 48.5 29.5 20.9 26.1 88.6 42.5 17.6 53.0 4.3 42.8 21.5 62.8 24.5 33.2 114.7 75.5 35.3 40.7 53.0 62.1 103.9 30.4 39.3 27.8 42.4 13.5 98.2 28.6 26.4 93.1 111.1 7.6 30.1 102.2 24.9 132.1 107.1 16.0 105.0 104.0 140.5 88.3 48.4 18.0 85.2 74.9 40.1 27.0 35.3 33.2 13.1 54.2 40.3 95.6 58.8 36.4 58.1 24.2 94.9 28.3 24.6 116.6 JAG1 "AGS, AHD, AWS, CD339, HJ1, JAGL1" ENSG00000101384 "Jagged canonical Notch ligand 1" P78504 20 10637684-10673999 "CD markers, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Notch signaling pathway" "Developmental protein" "Deafness, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 211.1;Endometrial ciliated cells: 197.4;Smooth muscle cells: 190.1;Squamous epithelial cells: 343.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HBEC3-KT: 219.2;hTERT-HME1: 131.1;U-251 MG: 187.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010343, HPA021555" Supported Approved "Golgi apparatus,Plasma membrane" NA NA 25000000 "Cluster 49: Eosinophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Golgi apparatus, Plasma membrane" "CAB010343: AB_649685, HPA021555: AB_1851969" "unprognostic (2.23e-1)" "unprognostic (2.04e-2)" "unprognostic (1.78e-1)" "unprognostic (4.15e-2)" "unprognostic (1.21e-1)" "unprognostic (6.42e-2)" "unprognostic (4.21e-2)" "unprognostic (8.94e-3)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (4.10e-6)" "unprognostic (5.48e-2)" "unprognostic (1.71e-3)" "unprognostic (2.22e-1)" "unprognostic (1.66e-1)" "unprognostic (3.10e-1)" "unprognostic (1.41e-3)" 44.2 10.1 10.3 13.0 9.5 21.8 30.3 8.4 12.0 44.0 8.9 23.7 13.8 27.3 19.5 52.4 27.0 21.6 20.7 12.8 9.8 21.7 6.2 23.9 8.4 12.4 14.2 20.3 22.0 20.9 8.2 67.9 10.0 25.9 23.0 22.1 15.8 26.7 9.8 57.2 13.6 23.6 9.7 23.3 25.1 4.5 12.1 9.3 19.9 22.8 15.6 28.5 50.0 8.5 4.1 20.6 63.1 78.1 11.8 11.3 2.3 2.4 11.9 3.3 1.8 18.5 11.2 0.7 59.0 2.4 17.7 85.8 9.4 219.2 2.7 0.2 4.5 7.0 2.2 87.9 5.8 28.4 0.5 4.6 63.7 10.6 131.1 12.5 21.1 0.3 0.1 8.8 6.0 0.2 0.0 20.2 18.2 68.7 20.3 5.3 3.9 13.1 29.9 25.6 2.8 2.1 6.3 4.4 26.2 49.8 0.3 3.3 80.5 14.2 9.9 11.8 187.9 3.6 0.6 0.9 9.1 10.3 11.3 0.0 0.4 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.2 0.0 0.0 10.3 9.5 8.4 12.0 12.8 9.8 12.4 14.2 10.0 9.7 12.1 8.5 73.0 41.7 15.4 5.9 1.1 104.6 54.9 76.3 211.1 9.7 13.2 29.1 20.6 30.0 34.4 16.5 43.8 16.9 6.8 64.3 1.9 31.6 5.0 197.4 22.2 102.5 5.3 0.0 6.9 30.4 1.0 41.9 76.0 96.4 7.0 2.7 60.0 1.8 4.2 21.9 9.2 12.8 20.3 5.9 33.9 9.6 21.5 9.1 14.2 22.5 2.8 11.9 2.1 24.6 1.3 97.3 18.3 33.8 4.3 24.5 7.8 2.3 30.2 69.1 85.5 46.7 190.1 0.9 3.2 343.9 106.8 2.2 4.3 107.2 39.1 33.7 JAK3 "JAK-3, JAK3_HUMAN, JAKL, L-JAK, LJAK" ENSG00000105639 "Janus kinase 3" P52333 19 17824780-17848071 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" "Adaptive immunity, Immunity, Innate immunity" "Kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, SCID" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 55.1" "Cell type enhanced" "Detected in many" "B-cells: 27.8;dendritic cells: 20.1;Macrophages: 17.9;NK-cells: 18.6;Plasma cells: 18.4;T-cells: 37.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 35.7;HEL: 15.9;HMC-1: 15.5;Karpas-707: 40.2;U-266/70: 15.4;U-266/84: 24.7;U-937: 24.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA070314 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 2: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cytosol" "HPA070314: AB_2686251" "unprognostic (5.59e-3)" "prognostic favorable (6.42e-5)" "unprognostic (5.71e-2)" "unprognostic (2.34e-1)" "unprognostic (6.13e-3)" "unprognostic (1.11e-3)" "unprognostic (4.21e-2)" "unprognostic (2.60e-1)" "unprognostic (2.38e-2)" "unprognostic (2.36e-1)" "unprognostic (3.58e-2)" "unprognostic (1.94e-1)" "prognostic unfavorable (2.89e-14)" "unprognostic (2.28e-1)" "unprognostic (2.21e-2)" "unprognostic (4.43e-2)" "unprognostic (7.61e-2)" 6.7 2.5 4.0 36.3 4.4 18.6 4.0 3.9 5.6 3.3 3.7 4.0 3.0 2.2 2.4 2.8 5.3 4.8 3.2 4.1 6.7 6.2 2.9 13.1 40.5 7.3 6.1 15.5 1.8 1.9 3.1 5.7 6.4 4.4 3.1 0.6 3.5 1.9 0.7 1.7 15.4 3.5 5.5 55.1 4.6 2.6 6.6 11.3 4.9 0.9 29.7 7.4 3.1 6.1 0.2 0.6 0.5 1.8 0.6 2.4 0.4 0.8 0.0 0.1 0.1 0.0 1.6 0.7 3.3 0.7 0.4 0.2 0.0 0.4 0.0 35.7 0.0 15.9 0.1 1.5 1.2 0.0 15.5 8.4 0.5 0.1 0.0 0.1 0.3 3.6 0.1 40.2 0.0 0.7 6.5 0.0 0.3 0.9 1.3 8.2 0.0 0.7 0.8 0.0 0.0 0.6 0.2 0.4 0.1 0.2 3.5 2.4 0.7 0.0 0.7 0.0 0.0 15.4 24.7 4.3 0.1 24.2 0.3 2.0 7.5 0.3 17.8 14.6 20.2 9.4 21.1 18.6 6.8 10.3 20.2 18.5 25.1 13.4 14.2 5.5 18.0 12.4 4.0 4.4 3.9 5.6 4.1 6.7 7.3 6.1 6.4 5.5 6.6 6.1 5.5 0.0 4.6 2.3 27.8 0.8 0.6 0.5 0.6 0.6 0.5 0.8 1.9 0.0 1.0 1.8 0.0 1.1 20.1 0.0 0.0 0.5 1.0 0.3 2.1 8.0 0.0 6.1 4.3 0.4 0.8 4.6 2.0 0.4 5.1 0.8 9.7 0.4 14.5 0.0 2.6 0.0 0.0 9.2 1.9 2.0 12.5 17.9 3.6 4.7 16.6 0.9 18.6 0.0 0.4 0.5 0.0 14.7 18.4 0.5 0.0 0.3 0.9 0.7 6.6 0.3 2.9 0.3 0.7 0.3 1.0 1.4 37.7 14.8 0.1 0.6 JAM2 "C21orf43, CD322, JAM-B, JAMB, VE-JAM" ENSG00000154721 "Junctional adhesion molecule 2" P57087 21 25639258-25717562 "CD markers, Disease related genes, Human disease related genes, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 63.5" "Cell type enhanced" "Detected in many" "Adipocytes: 173.8;Astrocytes: 81.6;Endothelial cells: 148.7;Hepatic stellate cells: 112.8;Microglial cells: 82.4;Oligodendrocyte precursor cells: 76.9" "Cancer enriched" "Detected in all" 9 "glioma: 27.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 25.5;BJ hTERT+: 16.5;HDLM-2: 16.7;hTERT-RPE1: 22.5;U-138 MG: 18.1;U-87 MG: 13.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028789, HPA077346" Supported "Nucleoplasm,Plasma membrane" NA NA 360000 "Cluster 11: Basophils - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 12: NES - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoplasm "HPA028789: AB_2732443, HPA077346: AB_2732341" "unprognostic (1.42e-1)" "unprognostic (6.39e-2)" "unprognostic (1.23e-1)" "unprognostic (1.73e-1)" "unprognostic (2.02e-2)" "unprognostic (1.53e-2)" "unprognostic (7.51e-4)" "unprognostic (2.61e-2)" "unprognostic (4.55e-1)" "unprognostic (1.02e-1)" "unprognostic (3.46e-2)" "unprognostic (3.81e-1)" "unprognostic (8.86e-2)" "unprognostic (5.71e-3)" "unprognostic (2.18e-1)" "unprognostic (2.20e-1)" "unprognostic (4.85e-3)" 20.5 15.8 16.6 3.7 21.5 0.3 16.8 24.0 21.8 16.8 12.8 17.8 6.1 18.5 11.2 7.1 16.1 12.9 19.2 19.2 22.0 9.2 2.2 15.5 3.6 25.9 23.1 16.1 2.8 4.3 8.1 63.5 21.3 9.4 7.9 7.1 6.1 15.4 7.8 5.5 10.7 19.6 26.8 1.6 10.2 17.6 25.2 2.6 10.3 13.2 5.0 11.6 13.2 23.0 0.0 0.0 25.5 0.1 1.0 0.2 0.5 0.8 16.5 2.0 7.6 0.0 0.0 0.1 0.0 0.2 9.7 0.1 2.2 0.0 4.6 16.7 0.7 0.1 0.1 0.1 0.0 0.1 0.1 1.4 0.0 1.8 0.1 22.5 0.0 0.6 0.0 0.2 8.0 0.0 0.4 0.1 8.1 0.2 0.0 3.2 5.3 0.1 0.0 0.0 0.4 3.7 0.2 0.3 0.0 0.3 0.9 0.2 0.0 18.1 1.7 0.1 2.5 1.8 0.1 0.0 13.4 0.1 0.7 0.4 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.6 0.1 0.2 0.4 0.6 0.1 0.4 0.0 0.1 16.6 21.5 24.0 21.8 19.2 22.0 25.9 23.1 21.3 26.8 25.2 23.0 173.8 0.0 2.3 81.6 0.9 7.5 1.4 0.0 2.2 1.4 1.4 9.1 33.2 0.0 0.0 3.7 14.6 0.3 0.5 0.0 0.0 0.2 16.5 1.0 4.7 148.7 0.0 0.0 15.2 0.2 5.3 28.5 0.5 2.1 0.0 4.5 112.8 0.5 1.3 0.0 45.0 0.0 0.0 1.8 10.7 15.6 9.9 2.8 16.0 82.4 0.0 1.8 0.0 76.9 4.1 0.1 0.0 24.5 1.2 1.5 0.0 0.0 0.7 5.2 0.0 5.7 7.0 6.7 4.4 0.8 6.7 0.8 1.6 2.1 0.0 1.2 JAML "AMICA, AMICA1, Gm638" ENSG00000160593 "Junction adhesion molecule like" Q86YT9 11 118193725-118225094 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 43.3;lymphoid tissue: 68.7" "Group enriched" "Detected in many" 4 "dendritic cells: 136.9;Kupffer cells: 125.8;Macrophages: 166.6;monocytes: 204.7;T-cells: 56.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "eosinophil: 3529.6" "Group enriched" "Detected in all" 5 "dendritic cells: 1017.6;granulocytes: 3529.6;monocytes: 1023.8" "Cell line enriched" "Detected in some" 5 "HMC-1: 28.0" "Region enriched" "Detected in many" 11 "cerebellum: 58.0" "HPA005854, HPA047919" Approved Supported "Nucleoplasm,Plasma membrane" NA NA 1400000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Nucleoplasm "HPA005854: , HPA047919: AB_2680209" "unprognostic (3.91e-3)" "unprognostic (1.55e-3)" "unprognostic (3.00e-2)" "unprognostic (1.28e-3)" "unprognostic (2.87e-3)" "prognostic favorable (3.11e-4)" "unprognostic (2.80e-1)" "prognostic favorable (3.92e-4)" "unprognostic (1.14e-1)" "unprognostic (3.17e-1)" "unprognostic (8.69e-2)" "unprognostic (5.08e-1)" "unprognostic (6.43e-3)" "unprognostic (8.96e-2)" "unprognostic (3.12e-2)" "unprognostic (4.10e-2)" "unprognostic (1.58e-2)" 13.9 4.5 0.9 68.7 1.0 20.9 5.6 2.4 2.1 5.6 2.3 16.8 17.8 3.5 1.5 8.5 4.3 20.4 3.2 0.7 0.9 3.4 9.8 43.3 31.1 1.3 0.9 1.8 2.9 1.0 1.6 7.8 1.0 4.4 22.7 0.3 2.9 3.6 1.2 4.6 32.1 15.3 1.0 60.0 9.4 1.5 1.0 24.3 2.9 7.8 31.6 24.9 3.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 5.9 0.0 1.4 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.7 0.0 0.1 0.0 2.0 0.0 0.0 28.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.3 3.1 0.4 3.1 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 0.0 0.2 0.0 137.4 1023.8 3529.6 60.1 616.5 386.5 7.1 107.4 113.7 1017.6 2.9 124.7 103.1 2121.1 24.3 310.3 765.1 191.3 844.1 0.9 1.0 2.4 2.1 0.7 0.9 1.3 0.9 1.0 1.0 1.0 1.1 1.2 6.4 34.2 0.0 6.9 0.0 0.2 0.0 0.0 0.3 0.9 1.3 0.0 2.8 5.6 1.8 0.0 0.3 136.9 0.9 0.0 0.1 1.0 0.4 0.2 1.3 0.0 5.0 0.0 0.4 0.4 1.8 2.6 0.6 15.2 0.0 5.7 2.8 31.0 0.0 0.0 0.2 0.0 125.8 0.0 1.1 0.0 166.6 0.0 0.0 204.7 0.0 9.2 0.0 0.0 0.1 0.1 0.0 6.3 0.1 0.6 0.8 2.2 0.2 0.0 0.4 0.5 2.2 5.9 0.2 0.0 0.4 56.0 0.0 0.1 0.2 JMJD4 FLJ12517 ENSG00000081692 "Jumonji domain containing 4" Q9H9V9 1 227730425-227735411 "Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 74.0;Late spermatids: 204.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027260, HPA052861" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 43: Testis - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Vesicles "HPA027260: AB_10602608, HPA052861: AB_2681975" "unprognostic (1.80e-1)" "unprognostic (1.37e-1)" "unprognostic (4.86e-2)" "unprognostic (2.29e-1)" "unprognostic (1.43e-1)" "unprognostic (2.86e-1)" "unprognostic (1.23e-1)" "unprognostic (6.19e-2)" "unprognostic (1.74e-2)" "unprognostic (4.31e-2)" "unprognostic (8.69e-3)" "unprognostic (8.68e-3)" "prognostic unfavorable (3.16e-4)" "unprognostic (4.45e-2)" "unprognostic (2.82e-1)" "unprognostic (2.05e-1)" "unprognostic (4.68e-1)" 6.8 12.8 8.5 4.8 7.9 3.6 7.1 7.7 9.4 6.2 8.1 6.2 4.3 8.1 4.8 6.8 7.0 4.1 7.4 8.6 8.4 7.4 11.9 5.2 6.9 9.0 9.2 7.9 9.6 5.8 10.0 4.0 9.3 9.7 2.4 1.6 8.7 5.6 10.2 6.0 6.2 4.2 8.3 9.0 5.9 14.8 8.6 6.5 6.4 4.7 4.4 6.8 4.6 8.9 18.4 26.4 8.4 9.3 9.0 5.1 31.0 11.3 11.6 17.0 10.4 22.6 15.2 24.3 16.8 10.7 9.1 18.1 5.8 17.9 2.0 13.2 29.4 14.9 13.3 17.8 15.8 15.7 7.1 9.0 11.1 16.2 11.8 6.7 8.8 17.5 19.7 7.8 8.3 15.4 19.5 8.3 14.6 13.9 42.2 17.8 10.3 21.9 10.1 16.7 16.4 11.1 10.8 37.4 14.5 4.3 30.2 16.9 7.7 8.6 8.8 10.6 21.0 14.5 5.0 9.3 8.6 7.6 24.1 3.2 7.2 2.8 11.1 7.4 12.2 8.7 8.4 7.7 6.6 8.6 13.1 11.4 0.7 14.3 4.1 13.2 10.2 8.0 8.5 7.9 7.7 9.4 8.6 8.4 9.0 9.2 9.3 8.3 8.6 8.9 7.0 6.4 7.2 4.6 7.9 4.1 8.0 8.6 1.8 14.0 16.6 13.2 3.7 4.3 7.4 7.3 0.0 13.1 7.2 8.8 5.9 21.7 74.0 5.2 11.0 6.9 9.0 13.9 4.4 28.9 14.0 9.7 10.7 4.9 7.0 12.7 6.8 14.5 16.9 11.8 3.3 6.9 2.0 7.6 2.1 204.9 11.5 6.1 12.4 2.8 11.0 12.2 13.4 3.0 2.1 23.7 5.6 4.1 14.7 11.0 12.9 12.5 7.7 14.7 6.6 6.7 8.2 36.1 7.5 7.4 4.7 9.6 7.3 13.3 7.3 7.5 JPT2 "C16orf34, FLJ13092, HN1L, KIAA1426, L11" ENSG00000206053 "Jupiter microtubule associated homolog 2" Q9H910 16 1678256-1702280 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 99.3;Ductal cells: 90.1;Endometrial ciliated cells: 107.3;Extravillous trophoblasts: 205.9;Glandular and luminal cells: 77.5;Pancreatic endocrine cells: 78.9;Syncytiotrophoblasts: 168.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041888, HPA041908" Approved Approved "Plasma membrane,Cytosol" NA NA 76000 "Cluster 22: NK-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041888: AB_10793937, HPA041908: AB_10794160" "unprognostic (1.49e-2)" "unprognostic (1.76e-1)" "unprognostic (1.30e-3)" "prognostic favorable (7.85e-4)" "unprognostic (3.60e-1)" "unprognostic (2.37e-2)" "prognostic unfavorable (9.14e-4)" "unprognostic (1.10e-2)" "unprognostic (3.14e-2)" "unprognostic (1.50e-2)" "unprognostic (1.12e-3)" "unprognostic (4.27e-2)" "unprognostic (1.01e-2)" "unprognostic (9.22e-3)" "unprognostic (1.65e-1)" "unprognostic (4.14e-2)" "unprognostic (2.78e-2)" 21.2 17.0 12.7 18.6 21.1 11.3 36.4 33.2 19.8 39.5 14.1 32.7 21.9 21.1 17.9 47.7 63.4 13.6 20.3 12.0 16.3 48.8 41.1 20.0 19.9 58.0 27.8 19.8 29.6 20.9 15.1 48.1 46.9 47.9 30.5 4.6 26.6 18.2 17.5 31.3 24.2 19.5 28.4 12.8 28.2 18.1 25.6 35.5 27.7 14.0 31.3 31.2 25.9 51.7 148.1 147.5 168.4 93.9 23.9 39.3 151.9 143.6 44.8 117.7 99.8 194.5 188.3 94.6 107.8 71.1 116.4 141.9 223.5 194.2 135.7 77.2 135.2 78.4 80.2 111.4 36.7 93.5 44.8 28.1 121.6 116.4 149.6 64.9 75.7 85.4 187.5 37.0 68.6 169.5 117.1 46.6 185.3 164.4 112.0 212.7 159.3 136.2 186.2 82.5 156.1 85.6 214.9 205.3 66.5 161.1 250.3 59.6 87.9 113.9 201.1 54.8 141.1 31.5 136.3 198.8 35.8 71.5 170.5 2.1 3.7 4.1 5.2 3.3 7.2 4.8 5.8 4.2 2.8 7.6 6.3 5.4 0.3 6.8 1.7 6.6 5.8 4.4 12.7 21.1 33.2 19.8 12.0 16.3 58.0 27.8 46.9 28.4 25.6 51.7 11.9 25.6 10.6 0.0 2.7 0.0 0.0 0.0 0.0 0.0 33.3 23.4 0.0 0.0 12.4 9.2 0.0 99.3 4.5 0.0 43.0 90.1 0.0 107.3 19.2 8.5 0.0 0.0 0.0 25.6 205.9 7.4 0.0 77.5 2.5 23.4 0.0 0.0 41.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.9 0.0 0.0 28.4 0.0 0.0 0.0 0.0 78.9 0.0 0.0 1.2 0.0 0.0 26.0 27.0 0.0 0.0 0.0 10.8 0.0 0.0 0.0 0.0 168.7 3.6 18.9 0.0 0.0 KARS1 "DFNB89, KARS, KARS2" ENSG00000065427 "Lysyl-tRNA synthetase 1" Q15046 16 75627474-75648643 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Host-virus interaction, Protein biosynthesis" "Aminoacyl-tRNA synthetase, Ligase, Transferase" "Charcot-Marie-Tooth disease, Deafness, Disease variant, Neurodegeneration, Neuropathy, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in some" 7 "Cardiomyocytes: 90.7;Cytotrophoblasts: 122.7;Extravillous trophoblasts: 143.3;Hofbauer cells: 89.5;Syncytiotrophoblasts: 110.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041345, HPA041550" Enhanced Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 82000 "Cluster 27: Non-specific - Gene expression" "Cluster 52: Non-specific - Ribosome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA041345: AB_10795589, HPA041550: AB_10794520" "unprognostic (1.56e-1)" "unprognostic (7.93e-2)" "unprognostic (3.36e-2)" "unprognostic (1.02e-2)" "unprognostic (5.39e-2)" "prognostic unfavorable (8.84e-6)" "unprognostic (6.24e-3)" "unprognostic (8.97e-3)" "unprognostic (1.18e-1)" "unprognostic (9.11e-3)" "unprognostic (8.71e-3)" "unprognostic (8.46e-2)" "unprognostic (7.86e-2)" "unprognostic (1.56e-1)" "unprognostic (1.03e-1)" "unprognostic (3.07e-2)" "unprognostic (2.13e-1)" 68.5 49.6 45.5 71.6 47.3 86.1 83.0 46.9 63.2 60.3 50.6 75.8 62.4 53.9 75.1 72.5 69.5 50.4 96.0 45.6 48.3 72.2 76.8 53.1 88.3 46.9 47.5 74.9 86.5 76.7 51.5 62.2 46.8 55.2 85.6 69.6 79.6 60.6 213.4 67.3 62.6 69.6 46.8 57.6 66.2 98.9 47.4 96.6 65.3 186.8 107.8 92.1 55.0 48.1 164.2 187.0 133.5 185.4 140.1 140.3 262.4 135.0 164.9 290.2 217.0 332.8 209.0 292.4 145.4 180.8 138.4 229.4 272.0 246.7 314.4 86.0 139.8 161.4 153.1 348.5 255.8 245.5 174.1 166.4 173.8 257.4 414.6 147.7 240.0 253.5 273.4 68.5 222.5 378.0 254.1 262.2 284.3 238.4 135.9 329.2 120.0 358.4 235.4 136.3 200.2 162.9 339.5 122.8 152.2 144.8 166.1 229.2 133.8 159.8 164.9 123.6 196.7 145.1 178.6 696.6 139.5 206.5 199.7 88.6 112.7 130.0 110.7 155.7 202.6 109.5 137.1 132.0 135.7 91.6 126.6 117.1 24.9 127.6 163.1 85.7 155.5 160.5 45.5 47.3 46.9 63.2 45.6 48.3 46.9 47.5 46.8 46.8 47.4 48.1 14.2 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 90.7 0.0 0.0 0.0 0.0 122.7 10.1 0.0 0.0 0.0 0.0 0.0 0.0 8.4 0.0 0.0 0.0 0.0 143.3 14.4 0.0 0.0 0.0 0.0 0.0 0.0 89.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 110.0 2.1 0.0 0.0 0.0 KATNIP "JBTS26, KIAA0556" ENSG00000047578 "Katanin interacting protein" O60303 16 27550133-27780369 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Joubert syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 2.7;Cardiomyocytes: 4.5;Cytotrophoblasts: 3.0;dendritic cells: 1.4;Extravillous trophoblasts: 2.6;Hofbauer cells: 2.6;Syncytiotrophoblasts: 2.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basophil: 14.3;eosinophil: 3.6;neutrophil: 9.9;NK-cell: 5.0" "Group enriched" "Detected in all" 5 "granulocytes: 14.3;NK-cells: 5.0" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035089, HPA035090" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Nuclear speckles" "Plasma membrane" "HPA035089: AB_10671509, HPA035090: AB_10601129" "unprognostic (1.81e-1)" "unprognostic (1.13e-1)" "unprognostic (1.55e-1)" "unprognostic (3.65e-3)" "unprognostic (7.76e-2)" "prognostic favorable (3.00e-4)" "unprognostic (2.72e-2)" "unprognostic (3.58e-2)" "unprognostic (2.02e-1)" "unprognostic (1.22e-1)" "unprognostic (2.94e-1)" "unprognostic (2.12e-1)" "unprognostic (1.47e-3)" "unprognostic (2.98e-1)" "unprognostic (2.11e-1)" "unprognostic (1.50e-3)" "unprognostic (1.45e-1)" 4.4 4.8 5.2 4.7 5.9 6.7 5.4 3.9 6.9 6.3 22.7 6.5 4.8 6.3 6.2 9.7 29.7 5.1 5.4 5.4 4.1 7.8 4.0 6.3 4.4 6.7 7.8 5.1 9.0 7.7 11.5 4.4 4.9 8.8 7.2 31.3 7.9 5.7 3.3 8.9 6.0 5.5 4.9 6.2 9.3 9.9 6.3 5.6 15.9 1.7 4.0 5.3 5.8 6.6 6.7 13.5 7.5 7.0 11.1 10.1 12.4 8.9 9.6 7.7 10.4 12.0 10.9 5.7 12.4 12.8 15.0 11.0 9.7 11.5 15.4 26.5 6.7 4.5 14.9 7.0 6.6 6.1 11.0 10.8 9.9 17.1 18.2 10.0 15.5 6.3 7.3 4.7 11.1 15.3 6.7 7.5 4.6 8.6 5.5 9.6 9.1 6.2 14.5 9.2 9.5 6.1 8.9 7.9 5.0 10.3 17.8 5.3 13.5 9.8 6.2 7.7 7.9 6.3 5.7 6.4 11.3 5.9 8.9 14.3 1.8 3.6 0.7 1.2 0.7 0.8 0.4 1.2 1.2 1.1 1.6 0.3 9.9 5.0 0.4 1.4 1.6 0.3 5.2 5.9 3.9 6.9 5.4 4.1 6.7 7.8 4.9 4.9 6.3 6.6 2.7 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 3.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 2.6 1.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 2.2 0.4 0.0 0.0 0.0 KCNG4 Kv6.4 ENSG00000168418 "Potassium voltage-gated channel modifier subfamily G member 4" Q8TDN1 16 84218667-84239750 "Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 9 "brain: 3.4;retina: 4.3" "Cell type enriched" "Detected in some" 14 "Bipolar cells: 56.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in all" 4 "cerebellum: 90.5;pons and medulla: 27.0" "Low region specificity" "Detected in many" HPA063516 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Nucleoplasm "HPA063516: " "unprognostic (3.54e-1)" "unprognostic (6.67e-2)" 0.1 0.4 0.6 0.0 1.0 0.3 0.0 3.3 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.7 0.0 0.0 0.0 0.1 3.4 1.5 0.1 0.0 0.0 0.0 0.0 2.4 0.0 0.0 4.3 0.0 0.0 0.1 0.3 0.0 0.0 1.3 0.0 0.0 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.3 0.2 0.0 0.1 0.0 0.0 0.6 1.0 3.3 0.4 0.5 0.7 3.4 1.5 2.4 1.3 0.8 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 56.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 4.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 KCNJ3 "GIRK1, KGA, Kir3.1" ENSG00000162989 "Potassium inwardly rectifying channel subfamily J member 3" P48549 2 154697855-154858354 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Voltage-gated channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 32.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 309.6;Horizontal cells: 124.5;Inhibitory neurons: 431.3" "Group enriched" "Detected in many" 5 "breast cancer: 12.2;renal cancer: 4.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.5;SH-SY5Y: 1.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024231, HPA064138" Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Mitochondria "Plasma membrane" "HPA024231: AB_1855558, HPA064138: " "unprognostic (1.45e-1)" "unprognostic (9.42e-2)" "unprognostic (2.66e-2)" "unprognostic (4.49e-4)" "unprognostic (8.89e-2)" "unprognostic (6.81e-2)" "unprognostic (7.24e-3)" "unprognostic (1.15e-2)" "unprognostic (4.25e-3)" "unprognostic (3.72e-3)" "unprognostic (3.33e-1)" "unprognostic (8.90e-3)" "unprognostic (3.75e-2)" "unprognostic (5.59e-1)" "unprognostic (2.32e-1)" "unprognostic (1.17e-1)" 0.5 1.4 5.7 0.1 8.7 0.1 0.3 32.7 17.0 1.6 4.7 0.8 10.7 0.1 1.1 0.1 0.4 1.3 15.1 14.6 3.7 10.5 3.1 0.2 0.0 2.2 4.3 0.1 2.1 10.4 6.8 0.0 2.4 6.5 0.8 5.0 0.0 11.3 5.3 0.1 9.5 0.2 1.6 0.4 0.7 0.4 4.1 0.0 0.1 0.2 0.0 0.4 0.6 6.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.4 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.3 0.2 0.1 0.1 0.1 5.7 8.7 32.7 17.0 14.6 3.7 2.2 4.3 2.4 1.6 4.1 6.4 0.3 0.0 0.0 38.8 0.0 0.8 5.3 0.0 0.0 10.9 3.7 1.7 49.0 5.7 0.0 20.2 14.6 0.0 0.0 0.1 5.9 0.1 0.3 0.0 0.0 1.3 31.1 0.0 309.6 3.2 0.0 5.4 0.0 0.0 0.0 0.0 0.0 1.3 0.1 124.5 431.3 7.0 0.0 0.0 2.1 0.0 6.2 0.6 1.8 5.6 0.0 0.7 0.0 32.6 6.8 0.0 1.2 4.1 0.0 6.1 16.2 8.7 0.0 3.9 0.0 8.0 1.6 0.4 0.3 0.0 1.8 0.0 0.8 1.9 8.4 4.7 KCNN2 "hSK2, KCa2.2" ENSG00000080709 "Potassium calcium-activated channel subfamily N member 2" Q9H2S1 5 114055926-114496500 "FDA approved drug targets, Plasma proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Transport" "Calmodulin-binding, Ion channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 27.8;brain: 20.8;liver: 31.3" "Cell type enhanced" "Detected in some" "Astrocytes: 36.2;Excitatory neurons: 149.9;Inhibitory neurons: 97.0;Oligodendrocyte precursor cells: 63.3" "Group enriched" "Detected in some" 7 "glioma: 3.5;melanoma: 3.2;prostate cancer: 12.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 17.5;NTERA-2: 6.4;SK-MEL-30: 12.9;THP-1: 21.8;U-937: 7.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038221 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: Liver - Metabolism" "Cluster 43: THP-1 - Innate immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA038221: AB_10673044" "unprognostic (9.22e-3)" "unprognostic (1.90e-1)" "unprognostic (2.04e-1)" "unprognostic (5.65e-2)" "unprognostic (1.43e-1)" "unprognostic (1.40e-1)" "unprognostic (2.94e-1)" "unprognostic (1.42e-1)" "unprognostic (1.11e-2)" "unprognostic (1.56e-1)" "unprognostic (1.09e-1)" "unprognostic (1.15e-1)" "unprognostic (1.66e-1)" "unprognostic (1.23e-2)" "unprognostic (4.61e-1)" "unprognostic (3.16e-1)" "unprognostic (4.25e-1)" 0.4 27.8 7.8 0.2 10.8 0.0 0.5 11.3 14.0 2.0 2.2 1.4 0.3 2.9 0.3 0.2 0.4 0.4 6.8 20.8 7.5 3.9 31.3 2.3 0.4 11.1 4.7 0.7 4.5 0.4 7.6 0.0 6.7 9.6 0.7 2.5 0.5 4.3 9.5 1.3 0.3 2.0 9.0 0.5 0.7 3.0 8.2 0.2 0.3 6.7 0.2 2.3 1.0 11.1 0.1 0.0 0.0 0.0 0.0 0.0 2.1 17.5 2.7 0.3 0.0 0.0 0.2 0.0 0.5 0.0 2.3 0.0 2.3 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 2.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 3.8 0.0 0.2 0.0 0.3 0.0 1.4 6.4 0.0 0.0 0.0 0.0 0.8 0.2 0.1 2.1 0.0 0.0 0.2 12.9 0.4 0.3 21.8 0.3 0.0 0.5 1.8 0.0 0.1 0.0 0.1 2.0 7.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.8 10.8 11.3 14.0 20.8 7.5 11.1 4.7 6.7 9.0 8.2 11.1 1.4 0.0 1.1 36.2 0.0 0.3 0.3 0.0 0.0 7.9 0.6 1.3 15.1 0.0 0.0 0.0 2.1 0.0 0.0 0.3 0.0 0.6 0.6 0.5 0.0 8.2 0.0 0.0 149.9 0.9 0.0 0.8 0.0 1.3 0.0 0.8 5.0 18.3 0.0 0.0 97.0 1.0 0.0 1.0 0.3 0.5 0.0 0.1 21.4 6.5 0.0 0.4 0.0 63.3 9.2 1.0 0.1 0.0 1.2 4.7 0.0 0.7 0.0 7.8 0.0 0.1 0.3 0.3 6.5 0.3 0.3 0.0 0.0 0.2 0.5 0.6 KCNN4 "hIKCa1, hKCa4, hSK4, IK, KCa3.1" ENSG00000104783 "Potassium calcium-activated channel subfamily N member 4" O15554 19 43766533-43781257 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, FDA approved drug targets, Hereditary hemolytic anemia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 130.8" "Group enriched" "Detected in many" 6 "Cytotrophoblasts: 231.1;Syncytiotrophoblasts: 763.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "CAPAN-2: 85.7;WM-115: 258.6" "Region enhanced" "Detected in single" "olfactory bulb: 1.9" "Not detected" "Not detected" "HPA013367, HPA053841, HPA059622" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 17: WM-115 - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA013367: , HPA053841: AB_2682278, HPA059622: AB_2684085" "unprognostic (1.23e-2)" "unprognostic (3.22e-2)" "unprognostic (4.29e-1)" "unprognostic (3.74e-3)" "prognostic unfavorable (2.68e-4)" "unprognostic (1.98e-2)" "unprognostic (7.33e-2)" "unprognostic (1.42e-2)" "unprognostic (2.48e-3)" "unprognostic (4.12e-2)" "prognostic unfavorable (4.56e-4)" "unprognostic (9.96e-3)" "prognostic unfavorable (1.05e-14)" "unprognostic (3.70e-2)" "unprognostic (2.17e-2)" "unprognostic (7.50e-2)" "prognostic favorable (1.75e-4)" 3.6 0.7 1.7 11.8 1.9 18.3 12.4 1.3 1.8 11.8 1.4 18.5 6.4 1.6 1.8 6.5 5.8 3.5 1.1 1.5 1.6 1.4 0.8 7.3 12.5 1.6 1.6 0.6 1.0 0.0 0.7 14.3 1.7 28.6 6.2 0.2 130.8 7.5 0.4 29.1 26.0 0.7 1.9 20.5 35.1 2.7 2.0 5.0 2.1 0.2 9.2 18.2 6.5 2.3 22.4 35.2 0.1 0.2 0.0 2.2 55.0 0.8 1.7 0.7 0.1 0.5 85.7 6.7 9.8 0.9 9.1 13.6 0.0 28.8 1.7 40.9 0.0 29.8 48.6 0.5 0.0 0.3 0.3 0.0 2.9 1.3 6.6 52.7 0.0 0.3 2.6 2.3 0.3 18.7 4.8 17.9 0.2 43.1 42.4 16.8 0.7 21.0 13.0 55.3 0.2 0.1 62.2 70.1 32.6 1.7 0.3 15.1 1.5 12.6 75.9 0.4 45.3 0.1 1.4 2.6 45.9 5.1 258.6 5.8 21.1 0.0 0.5 35.3 0.7 37.3 10.4 5.0 30.7 21.6 6.6 6.3 1.1 0.0 20.1 0.9 15.2 11.2 1.7 1.9 1.3 1.8 1.5 1.6 1.6 1.6 1.7 1.9 2.0 2.3 1.6 0.0 1.9 1.3 24.7 2.8 45.7 79.5 3.4 0.2 69.7 56.6 0.4 7.2 18.4 1.8 4.2 231.1 4.1 22.0 0.0 5.9 1.2 1.7 0.2 4.0 0.0 32.4 1.5 3.9 14.1 2.3 57.1 4.2 0.0 0.0 0.4 0.0 43.7 0.0 1.1 8.9 2.0 7.2 78.2 0.3 0.0 23.3 21.4 1.0 2.5 0.1 1.0 0.5 0.8 63.8 22.3 0.0 22.4 63.5 1.0 0.1 2.2 0.5 0.0 0.3 1.4 0.4 1.4 2.1 2.3 763.3 9.5 0.0 51.1 65.6 KCNQ1 "JLNS1, KCNA8, KCNA9, Kv7.1, KVLQT1, LQT, LQT1" ENSG00000053918 "Potassium voltage-gated channel subfamily Q member 1" P51787 11 2444684-2849105 "Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Calmodulin-binding, Ion channel, Potassium channel, Voltage-gated channel" "Atrial fibrillation, Deafness, Diabetes mellitus, Disease variant, FDA approved drug targets, Long QT syndrome, Short QT syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 197.1;stomach 1: 98.9" "Cell type enhanced" "Detected in many" "Granulosa cells: 47.6;Microglial cells: 71.2;Undifferentiated cells: 57.8" "Cancer enhanced" "Detected in all" "colorectal cancer: 42.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HMC-1: 33.4;OE19: 41.4;RPMI-8226: 23.2;U-266/70: 11.5;U-937: 13.4" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB018656, HPA048553, HPA071107" Enhanced Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Endoplasmic reticulum" "Plasma membrane" "CAB018656: AB_2131551, HPA048553: AB_2680438, HPA071107: " "unprognostic (6.02e-2)" "unprognostic (2.48e-1)" "unprognostic (6.39e-3)" "unprognostic (4.38e-1)" "unprognostic (1.86e-1)" "unprognostic (1.83e-1)" "unprognostic (3.46e-2)" "unprognostic (7.36e-2)" "unprognostic (8.07e-2)" "unprognostic (8.81e-2)" "unprognostic (1.58e-1)" "unprognostic (5.39e-2)" "unprognostic (2.46e-3)" "prognostic favorable (9.85e-4)" "unprognostic (3.99e-2)" "unprognostic (4.19e-2)" "unprognostic (5.27e-2)" 5.4 197.1 2.1 9.0 2.4 14.2 3.0 2.4 2.6 16.5 5.7 22.6 47.8 2.9 14.1 2.9 8.9 19.5 28.4 2.6 2.6 25.3 1.8 15.9 5.0 4.1 3.1 1.4 61.2 21.4 5.5 7.6 3.9 6.1 15.2 0.7 20.0 50.2 1.0 1.2 39.7 3.1 4.0 8.2 98.9 1.6 4.2 3.6 71.6 1.6 2.9 14.7 1.6 4.4 0.0 0.1 0.0 5.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.6 2.6 1.9 5.2 0.0 0.4 0.1 0.7 0.0 0.0 0.4 1.3 0.0 3.7 0.4 0.3 0.0 33.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.7 0.0 0.7 1.3 41.4 0.2 0.1 0.0 23.2 8.0 2.7 0.7 5.6 0.7 0.0 0.0 0.5 0.2 10.3 0.0 0.0 0.3 0.2 0.0 11.5 0.0 0.0 0.0 13.4 0.0 0.7 3.1 3.1 0.0 1.8 0.0 0.8 0.4 0.1 3.8 0.3 1.0 1.2 3.3 0.0 2.8 1.3 0.3 1.0 2.1 2.4 2.4 2.6 2.6 2.6 4.1 3.1 3.9 4.0 4.2 4.4 7.1 3.2 12.9 0.3 8.4 0.6 8.0 4.2 0.0 1.7 6.1 1.8 18.6 14.3 7.1 29.5 0.0 1.1 0.3 34.0 15.6 23.2 2.0 3.3 0.4 6.3 6.6 0.4 13.7 21.7 1.4 1.0 23.4 4.9 19.7 47.6 9.3 1.1 17.3 0.0 20.0 26.1 8.2 25.4 15.9 0.9 0.3 19.6 1.8 71.2 11.0 0.5 1.0 43.7 34.9 15.3 20.2 0.0 6.4 5.2 30.9 2.0 4.4 0.5 6.6 0.4 1.7 0.2 0.2 0.1 1.0 2.1 4.0 16.6 57.8 20.4 KCNV1 Kv8.1 ENSG00000164794 "Potassium voltage-gated channel modifier subfamily V member 1" Q6PIU1 8 109963636-109975771 "Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Potassium transport, Transport" "Ion channel, Potassium channel, Voltage-gated channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 7 "brain: 4.9" "Group enriched" "Detected in some" 6 "Enteroendocrine cells: 7.1;Excitatory neurons: 28.2" "Cancer enhanced" "Detected in single" "renal cancer: 0.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 36.6" HPA067233 Supported "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytokinetic bridge" "HPA067233: " "unprognostic (1.41e-1)" "unprognostic (1.81e-2)" "unprognostic (5.01e-4)" "unprognostic (2.30e-1)" "unprognostic (3.76e-2)" "unprognostic (1.13e-2)" "unprognostic (3.89e-2)" "unprognostic (2.27e-1)" "unprognostic (4.17e-2)" 0.1 0.1 1.9 0.1 4.9 0.5 0.1 0.0 4.6 0.0 0.0 0.5 0.1 0.1 0.5 0.1 0.1 0.1 0.1 3.3 0.0 0.1 0.1 0.1 0.2 0.0 0.0 0.3 0.4 0.1 0.3 0.2 0.0 0.2 0.4 0.7 0.2 0.1 0.1 0.4 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.1 0.3 0.0 0.1 0.0 0.0 1.1 0.5 0.6 0.4 0.2 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.0 0.4 0.5 0.1 0.0 0.1 0.2 0.1 0.3 0.6 0.1 0.0 0.2 0.3 0.0 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.6 0.0 0.1 0.2 0.2 0.2 0.1 0.2 0.0 0.2 0.0 0.8 0.2 0.3 0.1 0.1 0.0 0.1 0.4 0.2 0.0 0.2 0.5 0.4 0.3 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.5 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.9 4.9 0.0 4.6 3.3 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.4 0.0 0.0 0.0 7.1 0.0 28.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 1.3 0.0 0.0 0.0 0.4 0.0 0.0 0.0 2.8 0.0 0.0 0.0 1.5 1.7 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.3 0.0 KDF1 "C1orf172, FLJ34633, RP11-344H11.3" ENSG00000175707 "Keratinocyte differentiation factor 1" Q8NAX2 1 26949562-26960468 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Differentiation "Developmental protein" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 32.6;Ductal cells: 29.4;Syncytiotrophoblasts: 29.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 36 "B-cells: 3.4;T-cells: 6.2" "Cell line enhanced" "Detected in some" "A-431: 24.9;BEWO: 20.8;CAPAN-2: 22.7;HaCaT: 21.4;HBEC3-KT: 30.3;hTCEpi: 38.5;OE19: 39.3;SK-BR-3: 25.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA028634, HPA028639" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 30: Non-specific - Translation" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 30: Epithelial cell lines - Translation" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Cytosol "HPA028634: , HPA028639: AB_10599191" "unprognostic (2.58e-1)" "unprognostic (1.23e-1)" "unprognostic (6.46e-2)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.05e-1)" "unprognostic (1.64e-1)" "unprognostic (8.45e-2)" "unprognostic (9.09e-2)" "unprognostic (9.01e-2)" "unprognostic (2.73e-1)" "unprognostic (3.91e-1)" "prognostic favorable (3.04e-13)" "unprognostic (1.38e-3)" "unprognostic (7.83e-2)" "unprognostic (8.03e-2)" "prognostic favorable (4.40e-4)" 0.1 1.1 0.4 1.3 0.3 0.1 10.3 1.6 1.3 4.0 0.3 8.9 12.4 0.9 19.7 20.2 7.4 2.9 0.4 0.4 0.2 11.0 4.7 4.4 0.8 0.3 0.3 0.1 16.2 12.5 10.4 3.9 0.4 7.2 7.1 1.3 12.8 4.6 0.0 17.7 10.5 0.3 0.2 0.6 10.6 2.6 0.3 2.3 10.0 0.0 3.4 4.8 8.3 0.7 24.9 0.0 0.0 0.0 0.0 0.0 20.8 0.0 0.0 0.0 0.0 12.1 22.7 0.0 0.9 0.0 0.0 21.4 0.0 30.3 0.0 0.1 0.4 0.0 0.0 4.4 0.3 0.0 0.0 0.1 38.5 0.0 3.1 0.0 0.0 0.0 1.4 0.0 0.0 14.7 0.0 0.1 1.7 39.3 0.1 0.0 0.0 3.7 5.5 11.7 14.9 0.0 0.2 25.2 0.1 2.7 16.1 0.4 0.2 0.0 0.0 0.0 0.0 2.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 3.2 2.5 4.3 3.0 0.1 3.4 6.2 3.8 0.0 0.0 0.0 0.0 0.2 1.7 0.4 0.3 1.6 1.3 0.4 0.2 0.3 0.3 0.4 0.2 0.3 0.7 0.2 12.8 8.8 0.0 0.8 0.0 14.3 0.0 10.8 0.6 15.1 16.3 0.3 12.8 2.5 14.7 0.0 32.6 1.5 17.2 25.4 29.4 0.4 7.3 0.8 0.7 7.8 0.0 0.2 23.2 26.5 0.6 13.7 8.0 0.0 0.1 0.0 4.4 2.7 0.0 0.1 13.1 0.0 0.3 0.0 0.1 0.3 0.1 0.0 0.0 0.2 1.1 0.0 0.0 0.1 21.8 25.2 0.0 0.4 16.8 26.2 10.1 5.1 2.5 0.0 0.0 0.3 6.3 7.5 14.4 0.0 29.7 1.2 0.0 16.9 19.0 KIAA1958 FLJ39294 ENSG00000165185 KIAA1958 Q8N8K9 9 112486827-112669397 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 14.5" "Cell type enhanced" "Detected in many" "Astrocytes: 169.8;Excitatory neurons: 64.2;Inhibitory neurons: 55.1;Oligodendrocyte precursor cells: 127.6;Oligodendrocytes: 166.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020625 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 29: U-266 - Adaptive immune response" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA020625: AB_1852451" "unprognostic (3.09e-3)" "unprognostic (1.04e-1)" "unprognostic (1.61e-2)" "unprognostic (1.33e-1)" "unprognostic (7.48e-2)" "unprognostic (2.08e-2)" "unprognostic (2.01e-1)" "unprognostic (4.95e-2)" "unprognostic (1.14e-1)" "unprognostic (1.65e-2)" "unprognostic (2.73e-2)" "unprognostic (7.67e-2)" "unprognostic (5.48e-3)" "unprognostic (3.14e-2)" "unprognostic (1.82e-1)" "unprognostic (2.10e-2)" "unprognostic (2.58e-1)" 1.1 6.6 5.5 1.1 10.5 4.9 2.2 9.3 6.9 5.1 4.4 1.4 1.7 3.4 0.9 1.5 3.0 1.3 1.3 3.9 6.6 5.8 3.4 2.1 1.3 8.2 8.9 9.9 2.6 1.4 1.8 0.7 7.0 1.5 1.5 10.0 3.0 2.4 0.9 1.6 1.9 3.1 7.5 1.5 4.8 5.8 10.7 3.9 2.4 0.8 1.3 1.4 1.9 14.5 3.7 5.2 20.7 6.0 1.4 0.3 9.9 2.7 0.9 3.2 3.6 9.5 2.4 11.8 3.1 8.9 2.2 3.2 15.3 1.5 4.5 3.6 6.2 4.6 7.3 6.7 0.8 7.0 5.6 0.6 1.2 4.2 2.0 2.9 2.6 11.0 11.0 2.9 1.0 4.2 11.0 4.0 11.4 8.6 2.4 8.8 11.8 3.3 4.3 5.1 10.6 11.2 4.5 4.7 2.7 11.4 4.3 7.1 0.5 1.1 6.1 0.7 3.3 5.3 10.4 6.9 1.4 4.8 0.8 0.4 0.7 0.0 0.5 0.2 0.2 0.0 0.1 0.3 0.2 0.4 0.4 0.6 0.6 0.6 0.2 0.6 0.1 0.4 5.5 10.5 9.3 6.9 3.9 6.6 8.2 8.9 7.0 7.5 10.7 14.5 0.5 3.2 19.3 169.8 3.7 4.7 3.4 1.5 6.8 20.6 7.9 4.2 4.3 4.3 6.2 1.8 14.6 1.2 3.0 4.6 7.9 3.2 4.1 12.1 8.1 1.4 4.8 3.8 64.2 6.7 1.0 3.3 8.2 8.0 0.0 20.3 0.4 8.0 1.0 6.7 55.1 4.4 12.2 7.5 4.6 2.5 6.5 4.2 1.8 15.9 2.5 8.3 3.1 127.6 166.4 3.3 6.2 5.3 5.0 6.5 5.0 11.0 5.9 12.1 6.6 2.5 4.1 1.5 8.0 5.3 4.7 0.8 1.6 29.9 5.2 5.7 KIF12 ENSG00000136883 "Kinesin family member 12" Q96FN5 9 114086126-114099291 "Predicted intracellular proteins" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 162.3;pancreas: 85.4" "Cell type enhanced" "Detected in many" "Cholangiocytes: 105.8;Collecting duct cells: 90.1;Distal tubular cells: 80.3;Ductal cells: 43.3;Enteroendocrine cells: 64.1;Proximal enterocytes: 60.3;Proximal tubular cells: 79.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CACO-2: 9.6;OE19: 17.2;RPTEC TERT1: 44.8;SCLC-21H: 6.6" "Not detected" "Not detected" "Not detected" "Not detected" "HPA020192, HPA024127" Uncertain Uncertain "Golgi apparatus,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Golgi apparatus, Plasma membrane" "HPA020192: AB_1852467, HPA024127: AB_1852469" "unprognostic (5.29e-2)" "unprognostic (5.03e-2)" "unprognostic (3.34e-1)" "unprognostic (1.84e-2)" "unprognostic (5.80e-2)" "unprognostic (8.38e-2)" "unprognostic (9.81e-2)" "unprognostic (4.41e-2)" "unprognostic (1.90e-1)" "unprognostic (3.98e-2)" "unprognostic (1.69e-2)" "unprognostic (3.33e-2)" "unprognostic (1.10e-2)" "unprognostic (4.51e-2)" "unprognostic (2.38e-1)" "unprognostic (2.00e-1)" "unprognostic (1.12e-2)" 0.1 0.0 2.2 1.1 2.1 0.0 25.3 0.4 3.6 11.4 2.8 7.8 25.5 4.2 1.0 0.2 8.0 24.7 0.2 2.0 0.9 162.3 27.7 1.6 0.5 0.6 1.1 0.7 85.4 0.8 0.6 1.1 1.0 7.0 4.2 0.1 3.6 4.8 0.0 1.4 16.1 0.4 0.4 0.2 11.0 2.4 1.3 1.3 31.8 0.0 0.1 0.2 0.3 0.8 0.0 4.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 9.6 0.2 0.0 5.2 0.0 0.6 0.0 0.2 0.1 0.2 0.0 0.9 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 6.0 0.0 0.4 0.1 17.2 0.6 0.0 0.0 0.1 44.8 0.2 6.6 0.1 0.0 0.9 0.0 0.2 4.5 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.1 0.4 3.6 2.0 0.9 0.6 1.1 1.0 0.4 1.3 0.8 0.1 0.0 4.4 0.0 1.3 0.0 0.9 0.6 0.0 0.0 20.3 10.8 0.4 105.8 0.0 90.1 0.0 0.1 0.0 7.9 80.3 43.3 7.0 8.3 1.5 0.3 64.1 0.0 0.7 11.8 9.3 0.4 14.8 15.6 0.0 0.0 0.0 10.2 0.3 0.0 0.3 22.0 0.0 0.3 0.0 14.7 0.6 0.8 0.0 0.0 1.0 0.0 0.0 0.0 0.1 5.7 21.3 0.0 0.0 2.2 60.3 79.1 0.0 0.0 0.0 0.0 0.3 3.2 7.9 0.0 0.0 0.5 0.9 0.3 28.9 0.5 KIF17 "KIAA1405, KIF17B, KIF3X, KLP-2, OSM-3" ENSG00000117245 "Kinesin family member 17" Q9P2E2 1 20664014-20718017 "Plasma proteins, Predicted intracellular proteins" "Protein transport, Transport" "Motor protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 23.2" "Cell type enhanced" "Detected in many" "Adipocytes: 18.9;Early spermatids: 44.0;Hepatic stellate cells: 15.4;Late spermatids: 88.7;Sertoli cells: 19.7" "Cancer enhanced" "Detected in many" "testis cancer: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ hTERT+: 1.6;hTERT-HME1: 3.7;U-2 OS: 2.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA032085 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA032085: AB_10669917" "unprognostic (4.15e-3)" "unprognostic (8.60e-3)" "unprognostic (6.43e-2)" "unprognostic (1.12e-2)" "unprognostic (7.68e-2)" "unprognostic (3.70e-1)" "unprognostic (1.07e-2)" "unprognostic (1.04e-1)" "unprognostic (7.11e-2)" "unprognostic (1.08e-1)" "unprognostic (7.34e-3)" "unprognostic (8.73e-2)" "unprognostic (3.63e-3)" "unprognostic (1.08e-2)" "unprognostic (2.26e-1)" "unprognostic (1.22e-1)" "unprognostic (1.20e-2)" 0.0 0.2 2.3 0.0 2.2 0.0 0.0 0.0 3.3 0.3 1.8 0.2 0.1 0.4 0.0 0.0 1.8 0.0 0.0 2.3 4.9 0.4 0.1 0.2 0.0 0.6 1.4 0.2 0.0 0.0 0.6 0.0 0.4 0.2 0.0 0.2 0.0 0.3 0.0 0.0 0.1 0.5 0.3 0.0 0.0 23.2 3.1 0.0 0.4 0.0 0.0 0.1 0.1 0.0 0.8 0.7 0.4 0.0 0.0 0.0 0.1 1.2 1.6 0.6 0.4 0.2 0.4 0.0 0.5 0.9 0.3 0.0 0.6 0.4 0.4 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.1 0.3 0.5 3.7 0.4 0.0 0.0 0.3 0.0 0.8 0.0 0.0 0.0 1.1 0.0 0.8 0.0 0.0 0.0 0.3 0.0 0.3 0.6 0.2 0.0 0.1 0.7 0.0 0.0 0.0 0.2 2.3 0.2 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 2.2 0.0 3.3 2.3 4.9 0.6 1.4 0.4 0.3 3.1 0.0 18.9 0.0 0.0 0.7 0.2 1.7 0.0 0.1 0.6 0.0 0.2 0.3 2.8 0.0 0.2 1.8 4.2 0.1 2.8 0.1 0.0 0.0 44.0 2.8 0.3 15.2 0.0 0.0 11.0 0.0 0.1 0.9 0.0 0.2 0.0 0.0 15.4 0.5 5.1 0.0 2.8 0.0 0.0 1.6 9.8 88.7 1.2 3.2 1.8 1.9 0.2 0.0 0.0 0.0 0.7 0.0 0.0 3.8 0.1 0.1 0.1 0.3 3.5 0.3 19.7 0.5 2.7 3.2 4.3 0.1 1.3 1.6 0.2 5.2 0.1 0.2 KIF21A "FEOM1, FLJ20052" ENSG00000139116 "Kinesin family member 21A" Q7Z4S6 12 39293228-39443390 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 70.3;retina: 77.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 308.6;Cone photoreceptor cells: 308.6;Inhibitory neurons: 221.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 4 "gdT-cell: 7.1;MAIT T-cell: 3.4;memory CD4 T-cell: 4.4;memory CD8 T-cell: 7.3;naive CD8 T-cell: 4.8;NK-cell: 3.0;T-reg: 2.2" "Group enriched" "Detected in many" 9 "NK-cells: 3.0;T-cells: 7.3" "Cell line enriched" "Detected in many" 4 "SH-SY5Y: 187.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022079, HPA058432" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 77: Retina - Visual perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane" Cytosol "CAB022079: , HPA058432: AB_2683717" "unprognostic (1.08e-3)" "unprognostic (3.40e-1)" "unprognostic (2.06e-2)" "unprognostic (7.67e-2)" "unprognostic (1.13e-1)" "unprognostic (3.09e-1)" "unprognostic (2.24e-3)" "unprognostic (7.77e-2)" "unprognostic (3.17e-2)" "unprognostic (4.56e-3)" "unprognostic (1.36e-1)" "unprognostic (1.73e-2)" "prognostic favorable (8.07e-8)" "unprognostic (4.05e-2)" "unprognostic (1.66e-1)" "unprognostic (2.14e-1)" "unprognostic (2.34e-2)" 6.5 12.1 37.4 3.9 40.0 0.9 6.2 41.4 51.2 12.3 8.0 11.9 9.0 9.2 5.5 20.9 33.7 6.1 19.2 38.2 55.7 26.5 20.5 5.9 2.9 67.4 46.6 4.5 13.2 16.6 16.0 5.7 70.3 11.2 13.1 77.6 23.9 3.1 15.3 12.7 10.3 8.7 39.3 6.5 12.5 12.5 46.5 2.2 8.8 9.5 5.3 5.9 11.4 44.3 18.5 23.2 31.8 13.7 6.0 3.0 25.4 4.5 2.2 5.9 4.1 42.2 22.4 0.0 14.1 1.9 9.4 16.0 18.5 11.2 5.4 36.1 14.7 0.2 40.6 38.6 4.6 31.0 0.1 2.0 24.4 7.4 35.3 13.4 7.7 7.8 35.4 36.9 4.8 11.1 4.0 0.0 42.8 0.0 20.0 0.1 0.0 21.1 22.3 30.1 43.0 187.6 17.7 27.7 10.8 32.1 32.2 3.9 5.6 3.4 13.7 1.1 13.1 16.7 6.1 0.0 8.1 4.4 2.9 0.0 0.0 0.0 7.1 0.0 3.4 0.5 4.4 7.3 0.0 0.0 1.0 4.8 0.1 3.0 0.0 0.0 2.2 1.0 37.4 40.0 41.4 51.2 38.2 55.7 67.4 46.6 70.3 39.3 46.5 44.3 4.1 38.5 17.5 205.7 5.3 18.5 25.1 25.9 4.6 308.6 10.9 11.0 121.9 22.8 53.9 12.9 308.6 15.3 36.2 30.0 9.8 27.8 108.4 78.1 30.2 5.5 24.0 2.5 189.9 41.3 100.8 17.2 36.2 27.7 13.4 92.7 12.8 44.2 3.8 138.0 221.0 28.7 22.4 2.5 2.2 79.9 3.1 2.4 14.2 23.4 7.8 112.3 25.7 124.1 160.3 37.2 20.0 2.6 30.7 37.5 20.7 53.3 193.9 186.1 0.0 26.1 17.4 57.2 24.0 30.5 30.7 59.1 33.5 17.7 29.3 21.7 KIF26B FLJ10157 ENSG00000162849 "Kinesin family member 26B" Q2KJY2 1 245154985-245709432 "Predicted intracellular proteins" "Developmental protein, Motor protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 6.2" "Group enriched" "Detected in many" 4 "Inhibitory neurons: 282.0;Oligodendrocyte precursor cells: 378.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 18 "plasmacytoid DC: 1.8" "Lineage enriched" "Detected in single" 18 "dendritic cells: 1.8" "Cell line enhanced" "Detected in some" "HSkMC: 16.5;REH: 15.2;SH-SY5Y: 14.4;U-937: 7.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027709, HPA028478, HPA028561, HPA028562" Enhanced Approved "Plasma membrane,Microtubules" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Microtubules" "HPA027709: AB_10600215, HPA028478: AB_10601231, HPA028561: AB_10601960, HPA028562: AB_10602417" "unprognostic (3.66e-1)" "unprognostic (5.67e-2)" "unprognostic (7.90e-3)" "unprognostic (4.50e-3)" "unprognostic (3.23e-2)" "unprognostic (1.49e-1)" "unprognostic (4.17e-2)" "unprognostic (1.61e-1)" "unprognostic (9.63e-2)" "prognostic unfavorable (1.24e-4)" "unprognostic (8.30e-3)" "unprognostic (3.63e-1)" "unprognostic (1.38e-1)" "unprognostic (1.13e-2)" "unprognostic (5.77e-2)" "unprognostic (1.17e-4)" "unprognostic (7.22e-3)" 0.1 0.7 2.4 0.3 2.1 0.0 0.4 4.1 3.3 1.1 0.0 0.7 0.1 0.7 0.2 0.2 0.4 0.8 0.5 2.1 3.7 1.0 0.2 1.1 0.2 2.8 6.2 0.1 0.2 0.4 0.4 1.7 3.1 0.8 0.0 0.1 0.4 0.8 0.0 1.2 0.3 0.5 3.2 0.3 0.5 0.5 2.6 0.3 1.0 0.0 0.2 0.4 0.2 1.8 0.0 0.0 2.2 3.9 1.1 1.3 1.5 1.9 2.4 0.1 0.0 2.2 0.0 0.0 3.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.0 0.0 2.0 0.1 0.3 16.5 0.7 0.0 0.6 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.1 15.2 0.2 0.0 2.0 0.0 4.0 14.4 0.0 0.0 0.0 2.8 0.0 0.9 0.2 3.3 0.0 0.0 1.1 0.0 0.0 0.0 0.7 7.4 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 2.4 2.1 4.1 3.3 2.1 3.7 2.8 6.2 3.1 3.2 2.6 1.8 0.1 0.0 0.5 9.8 0.0 0.9 0.1 0.8 0.6 1.0 0.8 1.7 2.3 0.0 1.1 7.3 4.2 2.4 2.8 0.0 0.0 2.0 2.1 4.3 17.7 0.6 0.0 0.0 34.6 4.8 2.8 2.1 1.5 1.1 0.0 1.4 0.0 0.0 0.8 0.0 282.0 0.0 0.0 0.0 0.4 5.6 0.6 0.6 3.6 66.5 0.8 0.5 0.0 378.0 9.8 9.2 0.0 0.0 0.0 0.2 0.2 0.5 2.0 0.4 0.0 0.8 1.5 1.1 2.0 0.5 1.3 2.5 0.3 0.1 0.5 0.0 KISS1R "AXOR12, GPR54, HOT7T175" ENSG00000116014 "KISS1 receptor" Q969F8 19 917287-921005 "Disease related genes, G-protein coupled receptors, Human disease related genes, Potential drug targets, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Disease variant, Hypogonadotropic hypogonadism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 8.5" "Cell type enriched" "Detected in some" 9 "Extravillous trophoblasts: 41.9" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "K-562: 15.7;RPMI-8226: 37.4;SCLC-21H: 7.4;SH-SY5Y: 20.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in single" "HPA007156, HPA071913" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 25: RPMI-8226 - Immune response" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" Vesicles "HPA007156: , HPA071913: AB_2686471" "unprognostic (1.54e-1)" "unprognostic (3.01e-2)" "unprognostic (9.42e-2)" "unprognostic (2.15e-1)" "unprognostic (8.46e-3)" "unprognostic (9.23e-2)" "unprognostic (1.65e-2)" "unprognostic (3.23e-1)" "unprognostic (1.37e-1)" "unprognostic (1.16e-1)" "unprognostic (1.48e-2)" "unprognostic (7.17e-2)" "prognostic unfavorable (3.33e-6)" "unprognostic (1.87e-1)" "unprognostic (8.09e-3)" "unprognostic (1.05e-1)" "unprognostic (2.05e-2)" 0.0 0.0 2.9 0.1 1.8 0.0 0.0 0.9 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.3 3.8 0.3 0.1 0.1 0.1 4.0 2.2 0.0 1.3 0.3 1.1 0.1 3.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.4 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.7 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.3 4.1 0.0 0.0 4.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 15.7 0.0 0.0 0.3 0.1 0.0 0.6 1.2 0.4 1.0 0.0 37.4 0.0 0.0 7.4 20.0 0.0 0.0 0.0 0.0 0.4 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.1 0.3 0.0 0.0 0.0 0.0 0.0 2.9 1.8 0.9 3.4 1.3 3.8 4.0 2.2 3.9 1.0 8.5 0.8 0.1 0.0 0.0 0.0 1.0 0.1 0.1 0.5 0.0 1.1 1.2 1.4 0.5 0.0 0.2 0.0 0.0 0.4 0.2 0.1 0.0 0.7 0.0 0.3 0.1 0.0 0.0 0.0 0.3 0.2 41.9 0.1 0.0 0.4 0.0 0.1 0.0 0.1 0.7 0.0 0.7 0.0 0.0 0.0 1.5 0.0 0.0 0.3 1.8 0.0 0.0 0.2 1.0 0.0 0.0 0.1 0.0 0.0 4.2 0.2 0.0 0.0 0.0 1.8 0.0 0.0 0.4 0.0 0.3 0.3 0.3 1.6 0.9 0.2 0.1 0.2 KLK7 "PRSS6, SCCE" ENSG00000169035 "Kallikrein related peptidase 7" P49862 19 50976468-50984099 "Cancer-related genes, Enzymes, Predicted intracellular proteins, Predicted secreted proteins" "Hydrolase, Protease, Serine protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "esophagus: 94.7;skin 1: 201.2" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Basal keratinocytes: 5.0;Basal squamous epithelial cells: 4.6;Breast glandular cells: 9.4;Breast myoepithelial cells: 10.4;Squamous epithelial cells: 5.9;Suprabasal keratinocytes: 10.7" "Cancer enhanced" "Detected in many" "ovarian cancer: 139.8" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 5.0;CAPAN-2: 8.0;HaCaT: 31.7" "Not detected" "Not detected" "Not detected" "Not detected" "HPA018994, CAB026342, HPA062126" Enhanced Supported "Nuclear membrane,Plasma membrane" "Secreted in other tissues" NA NA 3700000 "Cluster 11: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane" "Nuclear membrane" "CAB026342: , HPA018994: AB_1852607, HPA062126: AB_2684691" "unprognostic (1.88e-2)" "unprognostic (6.41e-2)" "unprognostic (8.57e-2)" "prognostic unfavorable (8.06e-5)" "unprognostic (4.33e-3)" "unprognostic (2.28e-1)" "unprognostic (4.44e-3)" "unprognostic (2.99e-1)" "unprognostic (1.31e-1)" "prognostic unfavorable (1.16e-4)" "unprognostic (2.10e-1)" "unprognostic (2.82e-3)" "unprognostic (3.25e-1)" "unprognostic (4.47e-2)" "unprognostic (1.12e-2)" "unprognostic (5.60e-3)" 7.1 0.1 8.4 0.1 9.2 0.3 11.2 0.9 7.4 19.7 1.0 0.1 0.5 0.7 0.2 94.7 16.3 1.3 0.2 6.5 1.4 12.1 0.1 3.1 0.0 4.3 1.4 0.1 0.1 0.3 0.7 0.0 4.9 0.1 0.0 0.1 21.6 0.2 1.0 201.2 0.0 0.2 2.1 0.8 0.3 0.3 7.4 0.9 0.2 0.0 10.9 0.0 30.9 3.0 5.0 0.0 0.0 0.2 0.0 0.0 1.5 0.0 0.0 0.0 0.0 1.8 8.0 0.0 1.1 0.0 0.1 31.7 0.0 1.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.1 0.1 0.3 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 8.4 9.2 0.9 7.4 6.5 1.4 4.3 1.4 4.9 2.1 7.4 3.0 0.0 6.4 1.1 0.0 0.0 5.0 0.1 0.5 4.6 0.0 9.4 10.4 0.2 0.0 2.4 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 2.6 0.2 0.0 0.0 1.7 0.0 0.0 2.9 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 1.0 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.2 5.9 10.7 0.0 0.1 0.0 0.1 2.7 KNTC1 "KIAA0166, ROD" ENSG00000184445 "Kinetochore associated 1" P50748 12 122527246-122626396 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 42.3" "Cell type enhanced" "Detected in many" "Early spermatids: 30.4;Erythroid cells: 29.5;Plasma cells: 28.7;Spermatocytes: 40.7;Spermatogonia: 39.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA025241 Approved Supported "Plasma membrane,Cytosol" NA Yes "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA025241: AB_1852629" "unprognostic (1.17e-1)" "unprognostic (2.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.53e-2)" "unprognostic (9.34e-2)" "prognostic favorable (8.69e-4)" "prognostic unfavorable (4.79e-6)" "unprognostic (4.04e-2)" "unprognostic (7.20e-3)" "unprognostic (1.59e-2)" "unprognostic (4.78e-2)" "unprognostic (1.92e-2)" "prognostic unfavorable (7.89e-8)" "unprognostic (2.17e-2)" "unprognostic (3.08e-1)" "unprognostic (8.04e-2)" "unprognostic (1.74e-1)" 7.1 7.6 3.7 11.7 3.6 42.3 7.6 4.9 5.3 9.1 3.5 9.8 9.0 5.3 5.2 12.2 6.8 3.4 4.1 3.6 3.4 6.7 6.4 8.0 16.4 3.8 3.4 8.2 6.6 2.9 5.7 5.8 3.9 7.3 11.9 5.5 7.7 2.9 2.5 15.1 14.5 4.6 3.1 18.2 7.2 28.2 4.0 17.8 5.4 1.4 17.4 6.2 8.9 5.0 33.8 27.6 77.8 17.9 5.9 10.8 35.0 30.6 19.8 29.7 27.9 26.2 27.6 40.2 15.6 14.9 19.5 45.4 34.1 19.1 39.1 28.8 23.7 49.7 57.1 27.1 2.0 49.3 32.8 5.8 4.3 30.7 20.2 15.5 20.5 50.5 50.4 29.4 22.6 25.0 40.9 113.0 39.4 16.3 34.5 55.4 37.8 44.8 17.8 35.6 24.1 31.0 55.7 11.7 16.7 46.2 44.4 28.1 15.1 33.7 32.3 33.3 36.3 39.3 42.3 61.0 20.1 31.3 39.6 2.5 0.5 1.8 0.7 0.7 0.6 1.6 1.1 1.3 0.5 0.9 0.8 1.0 1.6 0.9 1.0 0.8 0.5 0.3 3.7 3.6 4.9 5.3 3.6 3.4 3.8 3.4 3.9 3.1 4.0 5.0 4.3 0.0 2.6 3.3 8.1 4.2 1.9 1.9 2.2 2.2 3.1 3.4 1.8 0.0 1.9 5.5 4.2 7.0 3.8 3.0 0.0 1.5 30.4 3.3 3.9 2.9 0.0 29.5 6.2 0.4 5.9 2.9 10.2 5.2 1.3 14.7 2.2 1.3 4.8 0.0 4.5 2.3 0.0 2.2 4.7 17.7 4.7 4.0 1.8 4.7 1.6 1.1 2.1 2.5 4.4 0.8 1.0 3.0 28.7 1.0 1.5 0.5 5.0 5.0 6.6 3.1 2.9 40.7 39.9 4.9 2.3 2.9 5.3 2.1 5.8 1.6 KRT75 K6HF ENSG00000170454 "Keratin 75" O95678 12 52424070-52434371 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 15 "skin 1: 27.5" "Cell type enriched" "Detected in some" 7 "Ductal cells: 20.4" "Cancer enriched" "Detected in many" 4 "head and neck cancer: 36.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "PC-3: 38.5;U-2 OS: 50.0" "Not detected" "Not detected" "Not detected" "Not detected" "HPA019367, HPA076201" Enhanced Approved "Plasma membrane,Cytosol" NA NA 1500000000 "Cluster 61: Skin - Cornification" "Cluster 9: U-2 OS - Unknown function" "Cluster 1: Pancreatic cells - Digestion" Cytosol "Plasma membrane" "HPA019367: AB_1852239, HPA076201: AB_2686786" "unprognostic (2.83e-2)" "unprognostic (2.81e-2)" "unprognostic (1.65e-2)" "unprognostic (5.79e-2)" "unprognostic (8.85e-3)" "unprognostic (2.67e-1)" "unprognostic (2.17e-2)" "unprognostic (1.72e-1)" "unprognostic (6.60e-2)" "unprognostic (9.20e-2)" "unprognostic (5.19e-2)" "unprognostic (2.45e-1)" "unprognostic (8.98e-2)" "unprognostic (1.94e-1)" 0.4 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 27.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.2 7.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 50.0 0.0 0.1 0.0 0.0 0.0 3.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.8 1.6 1.6 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 20.4 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 KRT77 KRT1B ENSG00000189182 "Keratin 77" Q7Z794 12 52689626-52703524 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 14 "skin 1: 273.0" "Cell type enriched" "Detected in some" 8 "Suprabasal keratinocytes: 20.2" "Cancer enhanced" "Detected in some" "testis cancer: 1.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 36 "HaCaT: 3.6" "Low region specificity" "Detected in many" "Not detected" "Not detected" HPA045934 Enhanced Approved "Nuclear membrane,Plasma membrane" NA NA 1200000000 "Cluster 61: Skin - Cornification" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 28: Keratinocytes - Keratinization" "Nuclear membrane, Plasma membrane" "HPA045934: AB_10960065" "unprognostic (3.52e-2)" "unprognostic (1.54e-1)" "unprognostic (1.41e-1)" "unprognostic (3.79e-1)" "unprognostic (2.61e-1)" "unprognostic (2.11e-1)" "unprognostic (2.06e-1)" 0.6 0.0 0.0 0.0 0.0 0.1 19.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 273.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.9 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 20.2 0.0 0.0 0.0 0.0 0.0 L1CAM "CD171, HSAS, HSAS1, MASA, MIC5, S10, SPG1" ENSG00000198910 "L1 cell adhesion molecule" P32004 X 153861514-153886173 "CD markers, Disease related genes, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Differentiation, Neurogenesis" "Developmental protein" "Disease variant, Hereditary spastic paraplegia, Hirschsprung disease, Mental retardation, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 42.8;intestine: 48.5" "Cell type enhanced" "Detected in some" "Collecting duct cells: 84.6;Excitatory neurons: 23.7;Horizontal cells: 33.7;Inhibitory neurons: 23.3;Melanocytes: 44.4" "Cancer enhanced" "Detected in many" "melanoma: 34.1" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 372.4;BJ hTERT+ SV40 Large T+ RasG12V: 200.8;HeLa: 258.1;RH-30: 162.6;RPTEC TERT1: 218.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB010896 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 67000000 "Cluster 24: B-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB010896: AB_609903" "unprognostic (1.33e-3)" "unprognostic (3.43e-2)" "unprognostic (2.75e-1)" "prognostic unfavorable (8.51e-10)" "unprognostic (2.04e-2)" "prognostic unfavorable (3.81e-4)" "unprognostic (9.44e-2)" "prognostic unfavorable (2.36e-6)" "unprognostic (1.13e-1)" "unprognostic (9.12e-2)" "unprognostic (8.52e-3)" "unprognostic (8.02e-2)" "prognostic unfavorable (1.17e-4)" "unprognostic (3.07e-1)" "unprognostic (6.31e-2)" "unprognostic (1.69e-1)" "unprognostic (7.47e-3)" 3.5 27.2 20.4 7.6 23.0 0.5 2.1 23.0 42.8 8.4 0.0 48.5 4.2 2.4 2.1 4.4 3.4 2.4 12.1 12.6 42.4 18.5 0.9 0.6 3.2 9.0 2.5 1.3 2.2 0.1 14.4 0.6 6.1 8.3 4.7 15.7 4.8 9.0 0.9 9.2 13.0 5.4 0.0 0.9 11.3 0.8 3.2 0.7 2.5 2.1 1.8 6.1 9.6 13.2 95.2 7.2 27.6 0.2 0.0 0.0 11.8 131.6 372.4 123.6 200.8 37.8 1.0 0.0 121.8 0.9 103.2 3.9 3.5 2.3 64.1 0.3 1.0 0.0 258.1 6.1 0.4 0.3 20.4 0.9 1.6 18.7 12.9 0.2 0.1 0.1 0.3 0.3 0.6 127.9 0.4 2.6 6.5 0.4 4.7 0.2 162.6 0.9 218.4 1.9 81.4 53.0 73.4 64.2 54.1 61.0 6.7 1.7 0.3 0.1 52.6 5.8 63.7 1.1 1.6 1.0 0.9 1.1 105.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 20.4 23.0 23.0 42.8 12.6 42.4 9.0 2.5 6.1 0.0 3.2 13.2 0.4 0.0 0.0 2.6 1.3 1.1 0.1 0.6 3.4 11.6 0.0 0.4 1.2 0.0 0.0 84.6 4.2 0.3 0.1 0.0 0.0 0.5 0.0 0.3 0.1 1.9 0.0 0.0 23.7 0.0 0.2 1.3 0.0 0.6 0.0 0.0 1.4 0.0 0.1 33.7 23.3 0.0 0.0 0.0 1.1 0.0 0.9 0.3 44.4 5.6 0.0 1.5 0.0 1.5 1.7 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.1 10.4 0.0 2.2 0.6 0.4 0.1 0.0 1.3 0.1 1.5 0.0 0.0 0.1 LAMA4 LAMA3 ENSG00000112769 "Laminin subunit alpha 4" Q16363 6 112107931-112254939 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Adipocytes: 115.7;Early spermatids: 114.7;Extravillous trophoblasts: 119.1;Fibroblasts: 149.2;Leydig cells: 166.5;Microglial cells: 124.6;Oligodendrocyte precursor cells: 160.4;Theca cells: 117.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 330.5;ASC TERT1: 512.5;HSkMC: 405.5;hTERT-RPE1: 256.0;HUVEC TERT2: 441.3;TIME: 404.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015693, CAB078156" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 320000 "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB078156: AB_2665814, HPA015693: AB_1852687" "unprognostic (1.87e-2)" "unprognostic (6.48e-2)" "unprognostic (8.37e-2)" "unprognostic (2.39e-2)" "unprognostic (1.04e-1)" "unprognostic (1.15e-1)" "unprognostic (2.52e-2)" "unprognostic (5.07e-2)" "unprognostic (4.59e-2)" "unprognostic (2.93e-2)" "unprognostic (9.06e-2)" "unprognostic (1.78e-1)" "prognostic unfavorable (2.00e-4)" "unprognostic (4.40e-3)" "unprognostic (1.85e-1)" "unprognostic (2.80e-2)" "unprognostic (1.15e-2)" 116.2 9.4 17.6 34.0 17.1 0.5 59.9 11.7 12.9 77.0 12.6 82.6 17.2 77.5 18.5 35.6 115.2 37.3 51.2 12.3 17.9 9.9 4.4 80.8 11.5 12.7 16.3 23.2 4.9 8.6 13.6 68.0 14.7 35.4 34.0 1.3 38.4 40.7 10.6 17.7 34.5 107.8 11.4 1.5 36.7 18.7 22.6 5.0 23.2 18.6 8.9 65.1 40.3 11.4 0.3 0.1 18.8 0.6 330.5 512.5 0.3 91.4 55.8 8.9 1.4 0.0 36.1 0.0 58.0 154.9 19.8 0.3 4.0 0.6 1.5 0.3 46.4 0.0 44.4 0.0 69.6 0.1 0.3 405.5 0.1 64.9 0.2 256.0 441.3 0.0 0.4 0.4 1.7 0.0 0.1 0.3 1.1 0.0 15.1 0.2 0.2 0.3 134.0 2.8 0.4 2.1 14.2 0.4 68.5 1.5 0.4 0.2 404.9 145.1 7.6 160.6 29.1 0.0 0.3 0.3 33.5 0.2 191.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.6 17.1 11.7 12.9 12.3 17.9 12.7 16.3 14.7 11.4 22.6 11.4 115.7 3.2 4.5 45.4 0.1 22.7 1.4 2.9 8.6 1.6 5.4 9.4 53.3 2.8 10.4 3.7 0.0 1.0 0.6 0.0 3.9 0.7 114.7 6.2 24.8 103.5 0.0 2.7 27.4 0.7 119.1 149.2 3.6 10.5 1.3 3.5 36.0 35.3 3.0 0.0 6.3 0.8 20.3 1.6 20.8 47.0 166.5 2.0 56.9 124.6 0.6 0.0 0.0 160.4 2.0 0.7 0.0 81.3 1.5 1.5 0.0 0.1 1.7 0.5 65.7 5.4 98.2 1.3 1.2 5.0 18.6 3.0 2.7 117.4 0.0 12.9 LAMC1 LAMB2 ENSG00000135862 "Laminin subunit gamma 1" P11047 1 183023420-183145592 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Cell adhesion" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 231.7" "Cell type enhanced" "Detected in many" "Fibroblasts: 187.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 1582.4;ASC TERT1: 863.5;HSkMC: 980.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001908, HPA001909, CAB004486, CAB078163" Enhanced Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to extracellular matrix" NA NA 100000000 "Cluster 37: B-cells - Transcription" "Cluster 82: Adipose tissue - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Endoplasmic reticulum, Plasma membrane" "CAB004486: AB_627870, CAB078163: AB_2665817, HPA001908: AB_1079229, HPA001909: AB_1079230" "unprognostic (1.46e-1)" "unprognostic (1.05e-2)" "unprognostic (8.30e-2)" "unprognostic (8.84e-3)" "unprognostic (3.75e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (1.54e-2)" "unprognostic (1.38e-2)" "unprognostic (2.71e-2)" "unprognostic (1.10e-1)" "unprognostic (1.80e-1)" "unprognostic (1.88e-3)" "unprognostic (1.10e-3)" "unprognostic (1.53e-1)" "unprognostic (1.54e-1)" "prognostic unfavorable (8.85e-5)" 117.2 16.4 6.3 34.9 7.2 1.1 79.3 9.2 7.1 55.1 13.8 78.3 16.0 63.2 19.3 44.5 63.8 54.7 61.7 7.2 8.7 19.4 13.8 58.7 15.3 6.9 7.7 36.1 19.2 20.0 9.5 231.7 6.0 31.3 34.3 3.7 28.1 50.9 50.5 40.8 48.9 102.3 6.4 8.4 51.1 18.7 8.6 14.7 40.3 60.1 12.0 66.9 47.7 5.4 52.5 83.5 268.4 76.7 1582.4 863.5 405.0 374.8 373.0 147.8 87.1 249.4 58.2 18.8 168.6 180.8 87.9 127.4 51.7 99.2 112.7 0.6 52.6 0.9 71.1 91.3 248.1 16.6 8.9 980.4 52.2 177.0 138.7 262.7 261.0 0.2 0.6 55.5 182.5 22.8 0.2 17.4 109.3 96.0 15.7 13.5 226.2 9.9 237.6 137.0 17.6 50.1 98.9 0.7 95.6 459.0 21.2 43.6 486.5 179.1 70.0 168.2 95.4 21.6 0.3 12.4 148.7 12.3 177.4 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 6.3 7.2 9.2 7.1 7.2 8.7 6.9 7.7 6.0 6.4 8.6 5.4 81.2 35.3 21.6 32.7 8.1 31.4 46.1 44.4 35.9 3.1 7.1 17.4 57.5 27.1 21.0 36.8 4.2 101.9 0.2 1.6 1.9 59.2 5.7 32.5 58.5 80.9 1.2 0.0 69.2 23.3 69.0 187.8 8.6 78.5 2.5 53.0 26.7 19.1 18.7 1.7 50.0 2.4 18.3 10.7 20.6 6.8 120.9 4.5 33.8 106.8 6.0 2.2 1.0 35.2 2.5 44.7 2.6 62.4 11.0 59.9 0.5 12.4 14.8 0.7 72.3 73.9 102.1 17.6 36.8 17.0 16.9 72.1 2.8 74.4 3.5 25.8 LAT LAT1 ENSG00000213658 "Linker for activation of T cells" O43561 16 28984826-28990784 "Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Adaptive immunity, Immunity, Mast cell degranulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 117.9" "Group enriched" "Detected in many" 6 "dendritic cells: 80.7;granulocytes: 78.9;Macrophages: 55.9;NK-cells: 152.4;T-cells: 151.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 19 "basophil: 307.7;gdT-cell: 303.4;MAIT T-cell: 212.5;memory CD4 T-cell: 295.1;memory CD8 T-cell: 307.2;naive CD4 T-cell: 276.0;naive CD8 T-cell: 266.9;NK-cell: 114.6;T-reg: 410.8" "Group enriched" "Detected in all" 142 "granulocytes: 307.7;NK-cells: 114.6;T-cells: 410.8" "Cell line enhanced" "Detected in many" "HEL: 189.8;HMC-1: 765.9;MOLT-4: 279.5" "Not detected" "Not detected" "CAB002223, HPA011157, CAB012978, CAB079960" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 140000 "Cluster 20: T-cells - T-cell receptor" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" "Golgi apparatus" "CAB002223: AB_563852, CAB012978: , CAB079960: , HPA011157: AB_1079237" "unprognostic (4.35e-3)" "unprognostic (5.17e-3)" "unprognostic (1.25e-2)" "unprognostic (1.21e-1)" "unprognostic (1.62e-1)" "unprognostic (7.15e-5)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (1.27e-1)" "unprognostic (3.25e-2)" "unprognostic (1.52e-3)" "unprognostic (5.33e-2)" "unprognostic (1.02e-8)" "unprognostic (1.04e-2)" "unprognostic (5.58e-2)" "unprognostic (3.25e-1)" "unprognostic (1.51e-4)" 8.1 4.4 9.1 23.9 9.6 17.5 6.6 9.0 11.9 15.6 8.1 31.3 9.2 19.3 5.2 8.1 11.6 9.6 3.9 9.2 8.5 15.3 10.5 14.1 65.9 9.2 8.5 7.7 5.7 2.0 14.2 3.9 9.0 21.6 5.2 3.5 7.8 9.5 4.2 10.7 22.7 5.7 8.0 32.0 13.4 4.1 9.7 117.9 17.6 1.6 29.0 24.7 13.3 8.9 1.0 2.3 1.5 2.5 3.7 2.4 4.9 5.5 1.4 1.7 2.2 2.3 3.0 0.7 7.2 2.2 0.6 2.9 2.6 1.3 0.8 1.6 3.3 189.8 5.4 3.3 1.0 5.9 765.9 2.1 3.8 1.7 0.7 2.8 0.9 62.7 2.6 21.7 0.8 5.6 279.5 38.3 3.4 0.4 2.7 3.2 0.8 24.9 1.9 1.6 5.3 1.0 0.9 1.8 2.7 1.4 2.7 31.7 3.6 3.6 18.0 3.9 1.3 7.6 7.0 3.1 45.5 2.7 2.9 307.7 1.4 0.7 303.4 1.5 212.5 1.7 295.1 307.2 1.1 1.7 276.0 266.9 14.6 114.6 1.3 1.9 410.8 196.5 9.1 9.6 9.0 11.9 9.2 8.5 9.2 8.5 9.0 8.0 9.7 8.9 5.2 0.0 13.1 4.6 6.2 7.1 2.1 1.1 2.8 11.0 3.7 4.3 1.7 7.2 3.1 9.2 6.2 2.6 80.7 1.2 1.9 1.7 0.3 1.5 2.3 4.7 0.0 16.6 4.7 0.5 0.9 3.0 7.7 2.7 78.9 4.9 8.6 2.9 14.3 6.7 5.5 1.5 0.0 7.3 9.4 0.1 1.5 55.9 10.6 5.6 9.2 3.0 152.4 3.0 3.5 1.0 0.7 0.7 17.0 2.2 1.3 1.3 1.3 9.6 0.0 3.0 3.8 1.7 2.1 1.9 5.3 2.7 151.7 1.7 1.4 1.3 LCTL "FLJ33279, KLG, KLPH" ENSG00000188501 "Lactase like" Q6UWM7 15 66547179-66565979 "Cancer-related genes, Predicted membrane proteins" "Sensory transduction, Vision" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.0" "Cell type enhanced" "Detected in some" "Astrocytes: 2.9;Early spermatids: 5.8;Late spermatids: 9.0" "Group enriched" "Detected in some" 5 "glioma: 1.5;melanoma: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "EFO-21: 5.6;hTERT-RPE1: 6.7;NTERA-2: 5.2;SuSa: 6.0;U-2 OS: 14.3;U-251 MG: 6.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA071640 Approved "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 9: U-2 OS - Unknown function" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" "Endoplasmic reticulum" "HPA071640: AB_2686428" "unprognostic (4.60e-2)" "unprognostic (5.46e-2)" "unprognostic (8.70e-2)" "unprognostic (1.56e-2)" "unprognostic (3.22e-3)" "unprognostic (3.53e-2)" "unprognostic (6.67e-2)" "unprognostic (1.06e-2)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "unprognostic (3.47e-1)" "unprognostic (4.51e-3)" "unprognostic (4.44e-16)" "unprognostic (6.06e-2)" "unprognostic (3.39e-1)" "unprognostic (5.48e-2)" "unprognostic (1.39e-1)" 0.1 0.1 1.4 0.2 1.5 0.4 0.1 1.2 1.5 0.1 1.0 0.2 0.2 0.1 0.1 0.1 0.0 0.2 0.0 1.3 1.3 0.1 0.1 0.0 0.2 2.1 1.4 0.1 0.1 0.0 0.1 0.0 1.8 0.1 0.0 0.3 0.1 0.0 0.7 0.5 0.1 0.0 1.5 0.1 0.1 0.3 1.6 0.0 0.1 0.0 0.0 0.0 0.1 3.0 0.3 0.2 2.8 0.2 0.1 0.1 0.7 0.7 0.0 0.0 0.3 0.3 0.4 0.4 5.6 0.2 0.5 0.6 0.0 0.0 0.1 0.2 0.1 0.7 0.9 1.4 0.0 0.2 0.3 0.3 0.0 0.3 0.0 6.7 0.0 0.2 0.3 0.3 0.1 0.1 0.2 0.4 5.2 0.4 0.1 0.2 3.1 0.3 0.0 0.3 0.3 0.2 0.1 0.3 1.6 6.0 0.4 0.5 0.2 1.4 14.3 0.5 6.4 0.1 0.2 0.2 1.9 0.6 2.7 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.6 0.2 0.1 0.1 0.1 0.0 1.4 1.5 1.2 1.5 1.3 1.3 2.1 1.4 1.8 1.5 1.6 3.0 0.0 0.0 0.0 2.9 0.7 0.4 0.6 0.0 0.0 0.6 0.1 0.1 0.3 1.5 0.1 0.0 0.0 0.1 0.6 0.2 0.0 0.1 5.8 0.2 0.3 0.2 0.0 0.0 0.2 0.0 0.3 0.2 0.0 0.3 0.0 0.5 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.6 0.3 9.0 0.6 0.1 0.0 0.0 0.0 1.4 2.1 0.5 1.0 0.1 0.0 0.0 0.0 0.8 0.2 0.0 0.0 1.4 0.0 0.6 0.4 1.6 2.1 0.0 0.3 0.3 0.9 0.3 0.1 0.4 LENG1 ENSG00000105617 "Leukocyte receptor cluster member 1" Q96BZ8 19 54155161-54159721 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Early spermatids: 98.8" "Low cancer specificity" "Detected in all" "Not detected" "Not detected" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 4.0;HaCaT: 5.7;HDLM-2: 3.6;HSkMC: 2.1;LHCN-M2: 3.1;U-87 MG: 4.1;WM-115: 2.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043541 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 23: Spermatids - Flagellum & Golgi organization" "Plasma membrane" Nucleoplasm "HPA043541: AB_10961190" "unprognostic (8.75e-2)" "unprognostic (4.36e-2)" "unprognostic (2.72e-2)" "unprognostic (2.30e-1)" "unprognostic (5.69e-2)" "unprognostic (1.91e-1)" "unprognostic (1.10e-1)" "unprognostic (8.73e-2)" "unprognostic (6.42e-2)" "unprognostic (5.22e-2)" "prognostic favorable (8.12e-4)" "unprognostic (7.51e-2)" "prognostic favorable (3.72e-4)" "unprognostic (2.21e-1)" "unprognostic (2.84e-1)" "unprognostic (4.82e-2)" "unprognostic (1.14e-2)" 8.2 8.9 0.2 0.0 0.3 0.1 8.1 0.5 0.3 9.3 0.0 9.4 0.0 8.8 0.2 6.6 9.5 0.0 12.0 0.1 0.2 9.1 8.3 7.1 0.0 0.3 0.3 10.3 10.1 0.1 8.6 0.0 0.9 8.8 0.2 0.2 7.2 0.1 15.2 7.4 8.4 0.0 0.3 11.2 10.0 14.7 0.3 0.1 8.3 0.0 0.1 9.5 7.5 0.5 0.0 0.0 4.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.1 0.0 0.1 3.6 0.6 0.0 0.0 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 3.1 0.0 0.2 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.1 0.0 2.2 0.0 0.6 1.1 0.4 0.5 0.6 0.4 0.9 0.7 0.5 0.6 0.6 0.5 0.8 0.7 0.0 0.4 0.4 0.1 0.2 0.3 0.5 0.3 0.1 0.2 0.3 0.3 0.9 0.3 0.3 0.5 28.8 19.2 8.8 2.3 31.4 20.6 22.1 28.6 11.4 10.1 15.2 14.5 7.8 17.2 17.6 18.4 0.0 27.5 30.9 33.7 23.5 21.5 98.8 23.6 18.6 24.2 27.0 17.7 1.1 28.4 14.6 18.3 10.7 17.6 54.6 15.3 29.3 17.0 30.6 6.7 1.2 27.2 34.6 21.8 23.9 15.6 22.4 22.3 21.4 0.0 26.9 19.4 51.5 1.5 4.7 26.1 28.0 15.1 18.0 15.6 35.9 38.2 26.4 15.6 39.5 14.5 24.8 37.3 31.2 10.8 21.5 42.8 38.7 21.3 18.8 16.7 LGR6 FLJ14471 ENSG00000133067 "Leucine rich repeat containing G protein-coupled receptor 6" Q9HBX8 1 202193799-202319781 "G-protein coupled receptors, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Wnt signaling pathway" "G-protein coupled receptor, Receptor, Transducer" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 17.5" "Cell type enhanced" "Detected in some" "Basal squamous epithelial cells: 23.3;Breast myoepithelial cells: 9.0;Cardiomyocytes: 10.5;dendritic cells: 6.0" "Cancer enhanced" "Detected in many" "ovarian cancer: 17.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "gdT-cell: 15.4;memory CD8 T-cell: 9.1;naive CD8 T-cell: 4.8" "Lineage enriched" "Detected in single" 37 "T-cells: 15.4" "Cell line enhanced" "Detected in some" "A549: 17.4;CAPAN-2: 15.4;HaCaT: 8.3;HeLa: 3.9" "Region enriched" "Detected in many" 9 "olfactory bulb: 24.4" "Low region specificity" "Detected in many" HPA008556 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 35: Non-specific - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA008556: " "unprognostic (4.72e-3)" "unprognostic (5.29e-2)" "unprognostic (1.21e-1)" "unprognostic (2.89e-2)" "prognostic unfavorable (4.35e-4)" "unprognostic (1.08e-1)" "unprognostic (5.13e-2)" "unprognostic (9.23e-2)" "unprognostic (1.12e-1)" "unprognostic (2.54e-2)" "unprognostic (4.01e-2)" "unprognostic (7.89e-2)" "unprognostic (1.00e-2)" "unprognostic (1.17e-3)" "unprognostic (2.08e-1)" "unprognostic (1.70e-1)" "unprognostic (7.83e-2)" 1.1 0.2 2.3 0.4 5.4 1.4 5.1 8.2 1.5 3.7 0.3 1.4 0.1 1.2 2.2 5.0 8.8 6.2 14.7 1.0 7.2 0.8 2.1 3.4 0.8 14.7 7.6 1.8 0.2 0.0 17.5 0.3 8.0 5.9 0.7 0.0 5.3 1.4 0.3 4.1 1.3 0.3 6.1 6.7 0.6 7.2 9.8 0.3 5.1 0.5 0.3 2.9 3.8 2.0 0.0 17.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.6 0.0 0.0 8.3 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.5 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.4 0.0 1.0 0.0 1.7 9.1 0.0 0.0 0.7 4.8 0.0 0.4 0.0 0.0 0.5 3.4 2.3 5.4 8.2 1.5 1.0 7.2 14.7 7.6 8.0 6.1 9.8 2.0 0.1 0.0 0.0 2.6 0.2 1.3 3.6 0.5 23.3 0.0 1.5 9.0 10.5 0.0 0.6 0.0 0.0 0.9 6.0 0.8 0.0 0.0 3.1 0.0 0.0 0.2 0.0 0.4 1.0 0.0 0.0 0.7 0.5 0.0 0.0 0.4 0.4 0.2 0.1 0.0 0.8 1.6 0.0 0.6 0.3 4.1 0.0 0.2 0.0 1.9 0.0 0.0 4.1 0.0 0.2 0.0 0.7 0.0 2.5 0.2 0.1 0.1 0.0 0.0 0.0 0.0 5.6 5.5 3.3 0.3 0.1 0.8 4.3 0.0 2.7 0.9 LHX6 LHX6.1 ENSG00000106852 "LIM homeobox 6" Q9UPM6 9 122202577-122229626 "Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adipose tissue: 15.9" "Cell type enhanced" "Detected in some" "Early spermatids: 77.2;Endothelial cells: 32.1;Inhibitory neurons: 46.0;Late spermatids: 225.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CACO-2: 13.2;K-562: 9.8;NB-4: 18.4;PC-3: 12.3;U-87 MG: 9.6" "Low region specificity" "Detected in many" "Group enriched" "Detected in many" 5 "amygdala: 6.5;basal ganglia: 7.1;cerebral cortex: 7.7;hippocampal formation: 7.2;hypothalamus: 2.2" "HPA047854, HPA058319" Approved Uncertain "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 31: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA047854: AB_2680183, HPA058319: " "unprognostic (2.96e-1)" "unprognostic (2.86e-1)" "unprognostic (8.06e-2)" "unprognostic (6.18e-2)" "unprognostic (7.72e-2)" "unprognostic (4.49e-2)" "unprognostic (5.83e-2)" "unprognostic (3.47e-1)" "unprognostic (5.94e-3)" "unprognostic (2.15e-1)" "unprognostic (2.98e-2)" "unprognostic (9.14e-2)" "unprognostic (5.64e-6)" "unprognostic (1.77e-3)" "unprognostic (1.96e-1)" "unprognostic (1.08e-1)" "unprognostic (3.51e-2)" 15.9 0.8 10.7 1.9 7.1 0.0 11.8 0.0 6.8 4.5 0.0 3.5 1.1 3.5 0.6 2.1 3.5 2.8 5.9 6.5 9.7 1.6 0.2 3.6 1.0 0.0 0.0 2.0 1.1 0.9 0.3 2.7 0.0 2.5 1.3 0.1 2.3 0.8 2.3 2.7 3.4 3.3 0.2 0.1 2.2 5.6 1.3 0.7 3.3 2.8 1.0 5.6 4.0 3.1 2.7 0.0 0.0 0.3 0.0 0.0 4.0 0.0 0.0 0.0 0.0 13.2 3.3 0.0 2.8 0.0 1.1 0.0 1.4 3.6 0.0 0.0 2.1 0.1 1.0 0.6 0.0 2.5 0.6 0.0 0.8 0.0 0.2 0.0 4.7 0.7 9.8 0.0 0.0 2.8 0.0 18.4 2.8 0.4 12.3 0.0 6.2 0.0 2.2 0.0 1.9 0.4 3.3 1.0 3.3 0.5 2.7 0.0 0.8 0.8 1.3 0.0 0.2 0.3 0.2 0.2 9.6 4.2 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.7 7.1 0.0 6.8 6.5 9.7 0.0 0.0 0.0 0.2 1.3 3.1 13.7 0.0 0.0 0.7 0.0 0.1 0.2 3.6 1.8 0.0 1.3 1.5 2.3 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 77.2 0.2 0.1 32.1 0.0 2.7 0.6 0.0 0.0 0.2 0.0 0.1 0.0 0.0 2.2 0.0 0.0 0.0 46.0 0.0 0.0 0.3 0.3 225.9 1.2 0.1 0.0 5.6 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.2 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.1 0.9 2.5 6.7 0.5 0.3 0.0 0.0 0.1 0.0 0.2 LILRA6 "CD85b, ILT8, LILRB6" ENSG00000244482 "Leukocyte immunoglobulin like receptor A6" Q6PI73 19 54236592-54242791 "Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 9.0;lymphoid tissue: 16.9" "Group enriched" "Detected in some" 4 "Hofbauer cells: 13.8;Kupffer cells: 31.7;Macrophages: 30.6;monocytes: 19.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "classical monocyte: 3.4;intermediate monocyte: 3.9;neutrophil: 8.2" "Group enriched" "Detected in many" 26 "granulocytes: 8.2;monocytes: 3.9" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 21000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (1.00e-1)" "unprognostic (8.38e-2)" "unprognostic (5.60e-2)" "unprognostic (3.31e-1)" "unprognostic (2.95e-2)" "unprognostic (1.14e-1)" "unprognostic (4.16e-2)" "unprognostic (2.51e-1)" "unprognostic (1.86e-1)" "unprognostic (1.75e-1)" "unprognostic (9.11e-2)" "unprognostic (1.51e-1)" "unprognostic (7.47e-5)" "unprognostic (7.76e-2)" "unprognostic (4.01e-3)" "unprognostic (1.90e-1)" "unprognostic (4.33e-2)" 3.3 1.1 0.0 1.3 0.0 1.6 1.1 0.0 0.1 0.4 0.0 1.0 0.1 0.5 0.0 0.3 2.2 0.2 1.1 0.0 0.0 0.7 1.3 9.0 0.0 0.0 0.0 0.3 0.5 0.0 0.4 0.2 0.0 0.5 0.0 0.0 0.9 0.0 0.4 0.3 0.8 1.4 0.0 16.9 0.8 0.2 0.1 0.0 0.5 0.0 0.0 1.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 3.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 8.2 0.0 0.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 4.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.6 2.8 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.3 0.0 5.3 0.0 0.0 0.2 0.4 0.0 0.1 3.8 0.0 0.7 0.9 13.8 0.0 0.0 0.0 0.0 31.7 5.2 0.0 0.0 30.6 0.0 1.0 19.1 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 LILRB3 "CD85a, HL9, ILT5, LIR-3, LIR3, PIR-B, PIRB" ENSG00000204577 "Leukocyte immunoglobulin like receptor B3" O75022 19 54216278-54223506 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Immunity" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lung: 27.0;lymphoid tissue: 49.9" "Group enriched" "Detected in many" 5 "Hofbauer cells: 63.4;Kupffer cells: 88.6;Macrophages: 88.8;monocytes: 71.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.8" "Group enriched" "Detected in many" 4 "granulocytes: 44.8;monocytes: 15.4" "Not detected" "Not detected" HPA026985 Approved "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "HPA026985: " "unprognostic (7.51e-2)" "unprognostic (3.52e-2)" "unprognostic (9.59e-2)" "unprognostic (4.53e-1)" "unprognostic (1.83e-3)" "unprognostic (5.28e-3)" "unprognostic (2.91e-2)" "unprognostic (2.55e-1)" "unprognostic (5.58e-2)" "unprognostic (2.35e-1)" "unprognostic (1.43e-1)" "unprognostic (1.63e-1)" "unprognostic (1.92e-8)" "unprognostic (2.18e-1)" "unprognostic (2.19e-3)" "unprognostic (1.84e-1)" "unprognostic (1.75e-1)" 9.9 3.4 0.4 8.3 0.4 14.6 2.9 0.4 2.1 1.2 0.9 2.7 0.3 1.2 0.3 1.3 5.4 0.1 3.4 0.4 0.4 2.3 4.1 27.0 0.3 1.2 0.8 1.0 1.9 0.0 1.3 1.2 1.3 1.7 0.0 0.2 2.4 0.0 1.1 0.8 2.6 0.1 0.6 49.9 2.3 0.5 1.8 0.6 1.6 0.0 0.2 3.2 1.6 1.4 0.3 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.5 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 15.4 0.6 0.1 14.3 0.2 0.1 0.3 0.0 7.2 0.1 0.0 0.1 44.8 0.0 5.6 0.5 0.0 11.6 0.4 0.4 0.4 2.1 0.4 0.4 1.2 0.8 1.3 0.6 1.8 1.4 1.5 9.6 13.0 0.3 2.2 2.4 1.2 6.5 0.0 0.7 1.6 2.2 0.4 4.3 8.3 1.8 0.0 1.5 2.1 0.6 0.0 0.3 1.3 0.8 1.9 3.0 0.0 0.8 0.2 0.6 6.7 2.9 0.0 2.2 7.6 0.5 1.8 3.2 63.4 0.0 0.1 1.9 0.0 88.6 8.4 4.1 0.3 88.8 1.8 1.9 71.2 0.9 3.1 0.0 0.1 0.2 1.3 0.7 2.1 1.6 0.4 0.4 5.2 2.9 6.6 4.3 1.3 0.8 1.5 0.1 3.0 1.2 3.8 2.6 2.0 0.4 LONRF3 "FLJ22612, RNF127" ENSG00000175556 "LON peptidase N-terminal domain and ring finger 3" Q496Y0 X 118974614-119018355 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 16.9;Gastric mucus-secreting cells: 17.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "MAIT T-cell: 3.8" "Lineage enriched" "Detected in single" 7 "T-cells: 3.8" "Cell line enhanced" "Detected in many" "GAMG: 12.2;K-562: 13.8;OE19: 15.2;PC-3: 16.0;SiHa: 14.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA050422, HPA061162" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" Nucleoplasm "Plasma membrane" "HPA050422: AB_2681122, HPA061162: AB_2732658" "unprognostic (1.80e-2)" "unprognostic (1.48e-1)" "unprognostic (1.24e-1)" "unprognostic (1.92e-1)" "unprognostic (4.24e-2)" "unprognostic (1.64e-1)" "unprognostic (6.06e-3)" "unprognostic (1.29e-2)" "unprognostic (3.21e-1)" "unprognostic (8.01e-2)" "prognostic unfavorable (4.32e-4)" "unprognostic (4.29e-2)" "unprognostic (2.31e-3)" "unprognostic (6.34e-2)" "unprognostic (6.16e-2)" "unprognostic (1.70e-1)" "unprognostic (1.27e-3)" 3.3 3.3 1.2 1.9 1.1 4.5 1.4 6.6 2.8 1.5 0.0 3.5 2.3 1.9 1.2 1.4 2.0 2.4 2.3 3.3 1.0 2.8 12.7 6.4 0.8 0.9 1.9 1.6 7.0 0.7 0.9 0.8 1.0 1.9 4.3 2.8 4.8 2.4 8.8 0.7 2.0 1.5 1.5 0.6 4.0 1.7 2.0 0.3 8.2 3.9 1.0 3.6 0.7 1.1 5.0 6.9 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.7 6.0 0.0 3.5 0.0 12.2 0.0 1.3 0.0 0.1 0.1 3.7 6.6 11.8 6.9 3.7 5.7 0.7 0.0 0.0 0.0 0.0 2.1 1.7 0.5 13.8 0.0 0.9 5.5 0.0 2.3 0.0 15.2 16.0 0.0 3.1 0.0 4.2 2.1 0.2 0.0 14.5 0.4 11.8 0.1 0.0 4.5 0.3 0.1 0.2 0.0 7.9 1.4 6.3 0.0 3.2 5.4 3.4 0.0 0.4 0.0 2.4 0.0 3.8 0.0 1.1 0.8 0.0 0.0 0.5 0.8 0.5 0.0 0.0 0.0 0.4 0.3 1.2 1.1 6.6 2.8 3.3 1.0 0.9 1.9 1.0 1.5 2.0 1.1 2.2 6.4 13.4 7.8 0.4 1.5 16.9 0.2 1.8 3.3 0.8 1.9 4.4 0.0 6.1 1.8 0.0 0.5 5.3 11.2 1.9 3.0 1.6 4.4 6.4 3.3 1.2 0.4 1.8 4.3 0.0 8.0 17.3 13.0 6.3 0.1 2.2 4.1 2.7 1.7 6.0 4.6 0.0 4.7 7.7 1.0 0.9 9.5 3.6 9.4 0.5 3.7 2.1 3.5 0.2 5.2 8.8 1.5 1.3 7.2 1.6 1.5 0.3 0.3 0.0 9.9 2.0 2.4 4.6 1.6 0.1 0.4 2.7 0.2 3.7 12.5 LPAR1 "edg-2, EDG2, Gpcr26, GPR26, LPA1, Mrec1.3, rec.1.3, vzg-1" ENSG00000198121 "Lysophosphatidic acid receptor 1" Q92633 9 110873263-111038458 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 358.4;choroid plexus: 122.2" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 626.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 5 "classical monocyte: 9.1;eosinophil: 19.0" "Group enriched" "Detected in many" 6 "granulocytes: 19.0;monocytes: 9.1" "Cell line enhanced" "Detected in many" "ASC diff: 582.0;ASC TERT1: 337.0;BJ hTERT+: 426.7;HSkMC: 246.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050667 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 70: Brain - Nervous system development" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear speckles" "Plasma membrane" "HPA050667: " "unprognostic (1.35e-1)" "unprognostic (1.41e-1)" "unprognostic (4.79e-2)" "unprognostic (6.08e-3)" "unprognostic (1.03e-1)" "unprognostic (1.16e-1)" "unprognostic (2.17e-2)" "unprognostic (2.10e-1)" "unprognostic (1.40e-2)" "unprognostic (4.13e-2)" "unprognostic (1.02e-1)" "unprognostic (4.29e-3)" "unprognostic (2.12e-2)" "unprognostic (5.42e-3)" "unprognostic (2.78e-2)" "unprognostic (9.97e-3)" "unprognostic (1.65e-1)" 30.5 13.3 251.0 18.8 315.0 0.2 25.9 208.8 318.6 57.7 122.2 24.5 13.9 17.0 17.1 15.2 15.8 14.1 24.1 199.5 201.3 9.6 2.6 16.3 17.6 299.6 277.5 12.1 6.6 2.2 5.0 38.8 249.2 21.0 18.3 0.8 16.7 23.6 6.6 20.1 18.3 20.5 224.0 14.8 11.8 6.9 266.2 6.8 16.5 17.5 17.2 27.6 31.7 358.4 11.7 22.2 30.4 0.1 582.0 337.0 0.0 151.6 426.7 104.1 46.8 3.0 1.8 0.0 0.1 157.7 18.6 45.5 0.4 118.5 85.0 0.0 4.1 0.0 1.1 0.0 157.1 0.1 0.2 246.6 6.8 51.4 96.9 62.3 1.8 0.2 0.0 0.2 80.8 0.1 0.0 0.1 5.9 0.0 121.6 0.1 22.4 0.0 23.5 20.6 0.9 7.2 3.1 0.0 0.0 6.2 10.4 0.5 0.1 48.9 1.3 35.3 0.1 1.5 0.0 0.0 7.4 0.0 54.9 1.5 9.1 19.0 0.0 3.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 1.9 2.1 1.3 0.2 0.0 2.1 251.0 315.0 208.8 318.6 199.5 201.3 299.6 277.5 249.2 224.0 266.2 358.4 1.9 0.0 1.1 6.2 0.2 13.0 15.5 8.5 4.0 0.0 3.4 6.0 1.4 1.5 9.1 0.0 0.0 0.5 0.3 6.6 1.9 1.8 1.4 3.6 40.4 1.9 0.0 0.0 1.0 2.9 0.4 61.4 6.1 8.7 0.0 0.0 2.5 0.0 3.3 0.0 15.6 3.7 4.1 4.1 15.1 2.7 38.8 3.6 14.2 141.5 12.0 1.0 1.0 1.0 626.8 2.0 2.9 70.7 0.7 12.7 4.5 0.2 3.0 0.2 0.0 13.3 6.3 0.3 2.4 15.2 9.2 0.8 1.2 0.2 4.2 6.7 LPIN1 KIAA0188 ENSG00000134324 "Lipin 1" Q14693 2 11677595-11827409 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Fatty acid metabolism, Lipid metabolism, Transcription, Transcription regulation" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 193.5;tongue: 137.2" "Cell type enriched" "Detected in all" 5 "Late spermatids: 1705.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024591, HPA038021" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 80: Striated muscle - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA024591: , HPA038021: AB_10669514" "unprognostic (1.97e-1)" "unprognostic (2.47e-1)" "unprognostic (1.32e-1)" "unprognostic (1.87e-2)" "unprognostic (9.17e-2)" "unprognostic (2.69e-2)" "unprognostic (8.20e-2)" "unprognostic (5.28e-3)" "unprognostic (1.09e-1)" "unprognostic (1.07e-2)" "unprognostic (2.45e-3)" "unprognostic (2.55e-2)" "unprognostic (1.06e-1)" "unprognostic (5.58e-3)" "unprognostic (1.25e-1)" "unprognostic (9.60e-2)" "unprognostic (4.02e-1)" 36.2 15.0 29.0 14.9 30.6 8.6 36.7 24.2 24.9 25.1 21.9 16.7 11.9 16.6 19.0 40.5 15.6 13.0 20.1 21.0 32.1 14.9 27.0 16.1 22.3 31.8 38.2 31.5 9.9 23.1 34.2 11.7 35.3 13.7 8.5 14.8 27.3 14.1 193.5 13.4 19.7 13.0 14.1 14.8 14.9 57.4 35.0 16.1 14.6 137.2 26.3 19.9 23.1 18.8 16.2 18.0 15.9 34.9 71.4 77.9 7.8 22.2 38.7 14.0 24.3 6.9 15.4 8.2 2.9 18.6 41.6 17.3 17.4 49.2 12.8 32.9 9.8 20.3 11.5 9.7 25.1 14.1 90.1 71.1 21.7 57.9 22.6 41.7 28.0 19.6 27.4 68.3 10.4 6.4 13.5 12.0 16.2 5.5 18.9 18.1 28.6 52.0 36.9 10.0 42.8 33.6 8.0 19.7 51.9 15.0 4.9 7.9 19.5 22.1 19.9 14.4 19.0 108.0 92.0 15.2 31.3 24.7 16.6 11.2 2.9 13.4 10.3 2.3 11.2 7.3 9.9 10.1 2.7 5.1 8.6 7.2 1.1 9.5 2.3 10.3 12.2 3.7 29.0 30.6 24.2 24.9 21.0 32.1 31.8 38.2 35.3 14.1 35.0 18.8 15.6 22.4 56.8 167.8 46.1 19.1 45.1 12.6 18.8 48.6 32.8 22.9 59.6 31.5 43.9 11.0 85.5 8.7 68.0 21.2 7.9 23.0 338.4 27.8 44.4 25.8 36.2 9.7 55.7 28.0 6.0 28.8 19.4 76.5 35.4 13.1 17.5 48.7 8.9 48.8 71.7 25.2 22.4 15.7 39.4 1705.8 119.0 25.5 17.8 21.5 15.4 14.7 66.9 41.7 43.5 36.5 29.7 179.8 76.0 34.9 5.4 4.8 52.0 49.0 32.9 32.4 18.4 20.6 19.7 5.5 11.9 12.3 73.2 26.6 16.3 31.3 LRP11 "bA350J20.3, MANSC3" ENSG00000120256 "LDL receptor related protein 11" Q86VZ4 6 149818757-149864359 "Predicted intracellular proteins, Predicted membrane proteins" Receptor "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 61.3;Respiratory ciliated cells: 107.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017267 Approved "Vesicles,Plasma membrane" NA NA 1500000 "Cluster 27: Brain & Skin - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Vesicles "HPA017267: " "prognostic unfavorable (2.31e-8)" "unprognostic (3.85e-3)" "unprognostic (1.68e-1)" "unprognostic (1.30e-2)" "unprognostic (5.17e-2)" "unprognostic (4.25e-3)" "prognostic unfavorable (2.01e-5)" "unprognostic (5.05e-2)" "unprognostic (1.47e-1)" "unprognostic (2.49e-1)" "unprognostic (3.29e-1)" "unprognostic (2.63e-1)" "unprognostic (4.76e-2)" "unprognostic (2.47e-1)" "unprognostic (6.75e-2)" "unprognostic (1.34e-2)" "unprognostic (4.23e-2)" 14.5 18.0 25.2 5.3 25.8 1.4 11.8 18.7 31.5 17.2 13.8 13.1 11.7 11.4 16.4 28.6 22.3 11.3 10.8 26.7 23.3 20.3 10.0 13.6 2.9 23.6 24.9 16.5 19.8 42.8 17.6 12.5 25.0 25.5 12.3 13.5 20.1 13.0 5.2 20.6 9.1 12.0 19.7 4.1 16.3 8.0 26.0 2.4 22.9 4.8 5.9 18.0 20.8 25.0 26.5 22.9 17.2 15.0 37.8 67.2 3.5 27.7 52.1 18.5 22.4 7.3 52.9 0.2 36.7 43.3 79.4 69.4 19.2 47.1 13.3 43.7 19.4 13.3 74.3 30.4 22.6 13.2 0.8 42.8 93.1 23.0 46.5 52.5 28.9 11.8 26.8 11.0 22.3 45.4 0.5 1.3 10.4 52.0 19.6 14.5 25.5 6.4 33.9 53.8 22.4 15.6 86.7 46.3 17.0 8.5 38.8 26.4 21.1 22.6 4.8 48.4 21.3 0.1 8.7 6.3 40.9 12.9 13.9 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 25.2 25.8 18.7 31.5 26.7 23.3 23.6 24.9 25.0 19.7 26.0 25.0 7.3 6.4 2.8 17.6 0.5 11.3 14.3 17.9 5.7 12.2 10.2 6.0 8.8 12.8 18.3 20.2 2.1 2.1 0.5 7.7 5.9 6.5 27.0 61.3 6.4 7.4 29.4 5.5 42.5 22.7 1.8 20.5 15.3 16.5 0.0 12.4 9.3 9.5 3.6 8.4 44.3 5.0 16.2 1.9 6.2 31.7 16.4 1.7 14.2 11.2 0.1 6.0 0.0 17.6 40.1 19.7 4.2 14.7 0.6 22.2 4.0 7.0 107.7 5.5 0.0 10.0 11.7 14.7 10.4 14.9 14.3 5.6 1.8 15.7 13.2 23.6 LRRC15 LIB ENSG00000172061 "Leucine rich repeat containing 15" Q8TF66 3 194355249-194369743 "Plasma proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 4.9;skin 1: 7.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 1.9;Endothelial cells: 1.0;Fibroblasts: 2.3;Hepatic stellate cells: 1.8;Langerhans cells: 3.0;Suprabasal keratinocytes: 1.4" "Cancer enhanced" "Detected in many" "breast cancer: 25.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "fHDF/TERT166: 120.6;U-87 MG: 62.7" "Not detected" "Not detected" "Not detected" "Not detected" HPA035503 Uncertain Approved "Vesicles,Plasma membrane" NA NA 1700000 "Cluster 31: Skin - Epidermis development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Vesicles "Plasma membrane" "HPA035503: AB_10961253" "unprognostic (3.20e-2)" "unprognostic (1.45e-2)" "unprognostic (3.11e-1)" "unprognostic (6.30e-2)" "unprognostic (1.19e-2)" "unprognostic (2.04e-1)" "unprognostic (7.11e-2)" "unprognostic (2.95e-2)" "unprognostic (1.84e-1)" "unprognostic (3.53e-2)" "unprognostic (3.97e-2)" "unprognostic (1.88e-3)" "unprognostic (1.22e-8)" "unprognostic (5.81e-2)" "unprognostic (1.11e-1)" "unprognostic (5.62e-3)" "unprognostic (7.54e-3)" 1.1 0.1 0.0 1.3 0.0 0.0 3.7 0.0 0.0 2.9 0.0 1.7 0.5 1.9 0.0 0.5 1.1 1.6 0.2 0.0 0.0 0.0 0.1 2.0 0.8 0.0 0.1 0.2 0.1 0.1 0.0 2.2 0.0 0.1 3.0 0.0 1.0 0.0 0.1 7.3 0.4 0.6 0.0 1.3 1.5 0.0 0.1 0.2 1.3 0.2 4.9 1.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.1 1.7 0.1 0.1 0.4 0.0 0.0 1.0 120.6 3.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.0 7.1 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.5 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.4 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 22.5 3.7 3.0 0.0 0.0 0.0 0.0 62.7 0.0 3.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.1 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 1.0 0.0 0.0 0.0 0.0 0.1 2.3 0.0 0.1 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.0 0.0 LRRC26 bA350O14.10 ENSG00000184709 "Leucine rich repeat containing 26" Q2I0M4 9 137168758-137170051 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "salivary gland: 290.0" "Cell type enriched" "Detected in many" 5 "Intestinal goblet cells: 598.0" "Cancer enriched" "Detected in many" 5 "prostate cancer: 47.6" "Region enriched" "Detected in single" 5 "cerebellum: 2.6" "Immune cell enriched" "Detected in single" 1177 "plasmacytoid DC: 117.6" "Lineage enriched" "Detected in single" 1177 "dendritic cells: 117.6" "Cell line enriched" "Detected in some" 6 "RPMI-8226: 130.9" "Not detected" "Not detected" "Not detected" "Not detected" HPA056312 Approved Supported "Nucleoli fibrillar center,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 25: RPMI-8226 - Immune response" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" "Nucleoli fibrillar center" "HPA056312: AB_2683098" "unprognostic (1.75e-1)" "unprognostic (2.28e-2)" "unprognostic (1.04e-2)" "prognostic favorable (4.82e-6)" "unprognostic (3.39e-1)" "unprognostic (1.67e-2)" "unprognostic (1.82e-1)" "unprognostic (2.13e-2)" "unprognostic (1.98e-1)" "unprognostic (1.06e-1)" "unprognostic (1.75e-1)" "prognostic favorable (3.48e-4)" "unprognostic (3.27e-1)" "unprognostic (2.29e-1)" 0.1 0.0 0.2 0.3 0.4 0.0 7.3 2.6 0.5 0.4 0.0 11.2 1.7 1.1 0.0 2.8 1.1 0.0 0.0 0.1 0.5 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.6 0.0 0.1 0.0 0.1 53.1 0.5 0.0 290.0 0.5 0.0 5.1 7.2 0.0 0.2 0.1 5.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.4 0.0 0.0 0.0 5.4 0.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.4 0.1 0.9 0.1 0.3 0.7 20.8 0.1 130.9 0.0 0.0 1.0 0.2 0.5 6.0 0.0 0.0 2.7 0.5 0.1 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 117.6 0.0 0.5 0.2 0.4 2.6 0.5 0.1 0.5 0.0 0.1 0.1 0.2 0.0 0.0 0.6 0.0 0.0 0.3 1.2 1.0 1.7 0.5 0.0 0.0 101.2 64.4 0.4 4.3 1.0 0.0 0.0 0.1 81.8 15.2 1.9 0.1 0.5 13.0 1.6 1.0 9.0 0.0 0.1 0.4 0.0 0.4 9.2 21.3 0.0 0.0 0.0 0.0 0.1 0.0 0.3 598.0 4.1 0.0 0.9 1.1 0.0 1.4 56.9 0.0 0.6 0.0 0.0 0.0 0.1 0.2 11.8 0.0 0.6 28.4 28.8 0.1 0.4 0.0 0.0 0.0 0.4 0.2 2.8 3.5 0.3 0.0 0.6 0.0 24.3 3.7 LRRFIP2 HUFI-2 ENSG00000093167 "LRR binding FLII interacting protein 2" Q9Y608 3 37052626-37183689 "Predicted intracellular proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 516.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035956, HPA042023" Uncertain Approved "Plasma membrane,Actin filaments" NA NA 150000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "HPA035956: AB_10671238, HPA042023: AB_2677802" "unprognostic (2.03e-3)" "prognostic favorable (6.31e-4)" "unprognostic (1.16e-2)" "unprognostic (7.90e-2)" "unprognostic (2.48e-1)" "unprognostic (2.97e-1)" "unprognostic (5.41e-2)" "unprognostic (1.82e-1)" "unprognostic (3.09e-2)" "unprognostic (2.56e-2)" "unprognostic (4.99e-3)" "unprognostic (1.98e-1)" "unprognostic (4.13e-3)" "unprognostic (2.62e-1)" "unprognostic (1.37e-1)" "unprognostic (4.84e-3)" "unprognostic (3.76e-2)" 23.4 24.0 43.7 20.1 46.9 44.3 22.3 43.6 49.0 46.0 33.6 38.3 35.4 31.8 19.7 52.6 25.8 22.0 75.8 38.8 44.4 24.0 48.5 27.0 18.1 43.4 42.0 27.4 19.2 33.3 18.6 20.8 44.8 41.0 34.2 36.0 28.5 24.3 97.9 37.0 36.2 31.5 41.0 45.0 26.5 71.8 46.4 18.8 27.5 45.3 23.2 24.2 40.9 60.9 56.6 30.8 34.9 27.7 45.5 69.3 30.5 149.9 148.2 82.6 94.3 29.0 25.3 22.2 24.0 145.4 40.8 28.8 25.8 74.2 134.3 49.7 20.2 39.8 44.0 28.6 64.8 31.9 23.3 31.1 52.1 107.8 110.4 45.8 58.2 34.0 32.3 37.8 69.5 14.4 27.2 17.0 23.0 23.0 39.2 13.0 99.2 22.6 58.4 21.7 12.6 19.9 57.9 53.0 49.4 28.0 30.6 32.6 56.5 63.1 42.6 93.4 71.5 29.1 57.1 33.9 37.1 28.1 91.4 20.5 21.4 33.8 8.8 14.9 11.3 9.7 9.3 9.5 14.1 8.5 6.8 8.3 19.2 16.9 26.9 7.9 13.0 11.7 43.7 46.9 43.6 49.0 38.8 44.4 43.4 42.0 44.8 41.0 46.4 60.9 47.8 28.9 36.5 98.6 29.1 136.1 143.0 41.3 113.8 36.3 64.7 53.2 123.1 38.6 53.7 23.9 29.2 29.2 28.7 117.2 64.6 89.8 516.2 78.9 44.0 59.9 54.0 60.0 169.8 94.3 46.1 57.4 37.8 127.3 52.6 29.4 56.7 58.8 24.9 122.8 197.7 45.6 28.5 35.6 128.3 330.7 42.3 48.2 74.7 62.8 67.7 51.9 30.9 130.7 309.0 109.9 90.1 57.6 45.8 325.6 125.8 46.1 36.2 51.9 39.5 32.4 72.8 159.9 73.4 139.3 170.5 39.3 34.1 90.0 66.0 303.2 LRRIQ3 "LRRC44, MGC22773" ENSG00000162620 "Leucine rich repeats and IQ motif containing 3" A6PVS8 1 74026015-74198187 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 9 "testis: 20.4" "Group enriched" "Detected in many" 5 "Early spermatids: 258.5;Late spermatids: 103.6;Spermatocytes: 204.8" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "GAMG: 7.9;JURKAT: 4.8" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA030799 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 43: Testis - Unknown function" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA030799: AB_10601337" "unprognostic (5.94e-3)" "unprognostic (6.00e-2)" "unprognostic (6.49e-3)" "unprognostic (1.63e-1)" "unprognostic (6.62e-2)" "unprognostic (2.78e-1)" "unprognostic (2.27e-2)" "unprognostic (2.27e-1)" "unprognostic (8.17e-2)" "unprognostic (2.44e-1)" "unprognostic (1.12e-3)" "unprognostic (1.71e-1)" "unprognostic (1.41e-1)" "unprognostic (1.05e-1)" "unprognostic (1.13e-1)" "unprognostic (1.88e-2)" "unprognostic (4.65e-2)" 1.6 0.7 0.5 0.7 0.5 0.1 0.7 0.6 0.7 0.2 1.2 0.3 0.2 0.2 0.3 0.1 2.1 0.4 0.3 0.4 0.6 2.0 0.9 0.3 0.7 0.7 0.8 0.3 0.2 1.2 0.5 0.2 0.7 0.4 0.2 0.5 0.7 0.4 0.1 0.1 0.2 0.0 0.6 0.4 0.3 20.4 0.7 1.0 1.5 0.5 0.6 0.2 0.1 0.7 0.2 1.0 0.1 0.4 1.0 0.4 0.6 0.6 0.4 0.8 0.9 0.1 1.4 1.4 1.2 0.1 7.9 0.1 2.1 2.0 1.0 3.5 0.0 1.3 0.3 0.7 0.1 2.3 0.7 0.7 1.0 1.4 0.5 0.3 0.4 4.8 1.1 1.9 1.4 0.0 0.9 0.3 1.1 2.5 0.6 1.1 0.8 1.4 1.2 0.1 1.0 0.7 0.1 0.1 3.1 0.2 0.9 1.3 0.1 0.1 0.7 0.5 1.2 2.0 0.7 1.1 1.5 0.2 1.1 0.0 0.0 0.8 0.9 0.5 1.1 1.6 1.0 1.1 0.1 0.7 0.9 1.3 0.0 0.4 0.1 0.4 1.6 0.3 0.5 0.5 0.6 0.7 0.4 0.6 0.7 0.8 0.7 0.6 0.7 0.7 1.0 0.0 1.5 2.0 2.8 1.1 1.2 4.0 0.0 1.0 2.0 2.8 1.2 2.8 2.6 0.0 4.2 1.7 0.5 0.3 13.7 1.5 258.5 21.6 0.8 0.8 3.0 0.4 4.1 1.7 1.5 0.3 0.0 1.5 0.0 3.2 0.7 1.8 1.3 0.0 3.9 0.6 0.0 0.6 0.2 103.6 1.8 0.5 0.0 1.9 0.8 1.2 2.1 2.0 4.0 0.9 0.1 1.5 0.6 0.9 0.1 6.3 36.0 0.7 0.0 0.2 1.5 204.8 31.3 0.0 0.1 0.3 1.5 3.6 0.7 1.2 LSMEM2 "C3orf45, FLJ38608" ENSG00000179564 "Leucine rich single-pass membrane protein 2" Q8N112 3 50279087-50288114 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 23.9;skeletal muscle: 16.5" "Cell type enriched" "Detected in some" 6 "Late spermatids: 283.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA079523 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 38: Heart - Muscle contraction" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA079523: " "unprognostic (2.84e-3)" "unprognostic (6.54e-2)" "unprognostic (2.36e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (2.30e-1)" "unprognostic (8.96e-2)" "unprognostic (1.02e-1)" "unprognostic (1.55e-2)" "unprognostic (2.65e-1)" "unprognostic (3.17e-2)" "unprognostic (2.82e-1)" "unprognostic (1.82e-1)" "unprognostic (2.46e-2)" "unprognostic (2.48e-1)" "unprognostic (6.49e-3)" "unprognostic (1.71e-1)" 0.4 0.4 2.9 0.1 4.8 0.4 0.3 3.1 3.7 1.3 1.8 0.5 0.3 0.7 0.2 0.5 0.7 0.2 23.9 3.2 3.2 0.8 0.2 0.4 0.0 3.7 3.7 1.2 0.2 0.0 0.1 0.1 3.4 0.4 0.1 0.3 0.2 0.4 16.5 0.2 0.3 0.4 2.7 0.2 0.3 3.9 3.8 0.0 0.2 5.5 0.0 0.4 0.8 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.9 4.8 3.1 3.7 3.2 3.2 3.7 3.7 3.4 2.7 3.8 6.0 1.0 0.0 0.6 0.7 0.3 1.0 0.2 0.2 0.0 0.2 1.5 0.9 4.4 0.0 0.8 1.8 0.0 0.1 0.3 0.9 0.0 0.1 40.5 3.3 0.6 0.8 0.0 0.0 0.2 0.2 0.1 0.4 0.0 10.1 5.1 0.2 0.0 0.3 0.1 0.0 0.2 0.3 0.0 0.3 0.4 283.1 1.2 0.3 1.8 0.0 0.0 0.5 0.0 0.0 2.8 0.2 0.0 0.7 0.0 0.4 1.5 0.1 0.2 0.2 0.0 1.4 4.7 1.8 1.1 0.4 1.3 0.1 0.2 0.1 0.7 0.1 LST1 "B144, D6S49E, LST-1" ENSG00000204482 "Leukocyte specific transcript 1" O00453 6 31586124-31588909 "Predicted intracellular proteins, Predicted membrane proteins" "Cell shape, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "bone marrow: 100.3;lung: 48.8;lymphoid tissue: 181.9" "Group enriched" "Detected in many" 11 "Hofbauer cells: 407.1;Kupffer cells: 1326.9;Langerhans cells: 1240.5;Macrophages: 871.6;monocytes: 1096.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 1746.7" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HEL: 39.3;HMC-1: 73.6;MOLT-4: 39.6;NB-4: 76.2;THP-1: 179.9;U-937: 92.9" "Low region specificity" "Detected in all" HPA079451 Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA079451: " "unprognostic (1.08e-2)" "prognostic favorable (7.89e-4)" "unprognostic (6.99e-2)" "unprognostic (4.16e-3)" "unprognostic (3.13e-1)" "unprognostic (3.92e-2)" "unprognostic (3.65e-1)" "unprognostic (7.06e-3)" "unprognostic (2.81e-3)" "unprognostic (2.12e-1)" "unprognostic (1.70e-1)" "unprognostic (1.28e-1)" "prognostic unfavorable (5.97e-5)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.62e-4)" "unprognostic (1.03e-1)" "unprognostic (1.95e-1)" 15.2 10.2 4.3 22.0 4.3 100.3 7.9 4.6 7.2 5.6 5.0 7.9 7.1 3.7 1.4 5.5 6.6 3.1 7.6 4.6 5.5 10.8 14.4 48.8 13.8 6.1 4.9 3.0 4.7 0.9 6.1 4.7 6.6 8.9 3.0 0.5 6.9 2.3 2.1 7.8 15.0 5.1 5.4 181.9 5.7 1.8 5.2 15.1 4.6 1.9 7.1 9.1 5.1 6.0 0.3 0.6 0.0 0.8 0.0 0.0 0.0 0.0 0.3 0.0 0.5 0.0 0.2 2.5 0.6 0.0 0.0 0.5 0.3 0.4 0.3 12.9 0.0 39.3 0.0 0.0 0.7 29.3 73.6 0.0 0.3 0.1 1.2 0.3 0.9 0.8 0.1 0.2 0.0 0.0 39.6 76.2 0.1 0.0 0.0 18.4 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 179.9 0.3 0.0 0.4 0.0 0.2 0.1 0.0 5.9 0.0 92.9 0.0 112.2 419.7 681.6 9.4 1273.9 80.7 32.8 15.9 20.2 392.9 21.9 10.9 9.0 1133.0 21.6 1746.7 69.9 12.0 541.6 4.3 4.3 4.6 7.2 4.6 5.5 6.1 4.9 6.6 5.4 5.2 6.0 5.4 35.3 86.7 0.7 43.7 35.2 0.3 0.2 0.0 0.3 3.2 12.2 1.9 7.2 13.0 11.0 0.0 2.9 42.8 1.0 0.0 0.6 1.5 0.4 1.9 12.9 0.0 15.1 0.2 0.2 3.8 9.2 1.5 0.4 70.3 0.1 22.9 5.8 407.1 0.0 0.3 0.0 2.0 1326.9 1240.5 5.4 3.7 871.6 44.4 24.4 1096.6 0.7 60.8 0.5 0.1 0.1 1.1 1.2 4.7 1.0 0.0 3.8 11.0 0.2 26.3 2.2 2.8 2.4 4.6 0.4 28.3 5.3 43.6 0.0 0.4 0.3 LTB4R2 "BLT2, BLTR2, JULF2, NOP9" ENSG00000213906 "Leukotriene B4 receptor 2" Q9NPC1 14 24305734-24312053 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in many" "esophagus: 37.7;skin 1: 46.4" "Group enriched" "Detected in some" 4 "Basal squamous epithelial cells: 18.2;Squamous epithelial cells: 15.7" "Cancer enhanced" "Detected in many" "head and neck cancer: 4.1" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HaCaT: 15.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB022689, HPA029680, HPA072921" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "CAB022689: , HPA029680: AB_10603013, HPA072921: AB_2686557" "unprognostic (2.01e-1)" "unprognostic (1.04e-1)" "unprognostic (9.53e-2)" "unprognostic (8.82e-2)" "unprognostic (1.42e-1)" "unprognostic (1.12e-2)" "unprognostic (1.40e-1)" "unprognostic (7.22e-2)" "unprognostic (1.36e-1)" "unprognostic (1.37e-1)" "unprognostic (1.48e-3)" "unprognostic (7.18e-2)" "unprognostic (7.05e-11)" "unprognostic (1.84e-1)" "unprognostic (1.04e-1)" "unprognostic (4.23e-2)" "unprognostic (1.19e-1)" 5.1 5.8 0.4 2.1 0.5 5.4 4.7 0.5 0.4 15.8 0.4 2.7 2.6 3.0 0.8 37.7 4.0 0.9 2.2 0.3 0.3 2.8 4.0 4.7 2.0 1.2 0.4 4.9 4.7 0.2 3.9 1.0 0.5 5.0 0.5 2.1 11.7 1.2 3.0 46.4 5.1 0.5 0.5 13.5 2.7 4.2 0.6 1.7 3.9 0.1 3.2 2.7 21.6 0.8 2.4 3.9 1.6 1.7 0.3 0.5 7.1 0.8 0.4 1.2 0.7 3.1 1.3 2.9 1.4 0.5 1.6 15.0 1.1 2.5 0.8 3.7 4.4 2.0 3.7 1.5 0.4 3.4 3.7 0.5 3.1 1.7 2.0 1.0 0.5 5.3 2.6 3.3 0.5 4.4 1.8 3.5 0.9 0.1 4.7 7.4 1.5 1.7 0.3 2.8 3.1 1.5 1.5 1.8 1.3 1.7 3.4 2.5 1.5 2.3 2.8 3.6 1.3 7.1 2.1 4.7 0.5 5.5 1.8 0.0 0.5 0.3 0.6 0.3 0.3 0.0 0.5 0.5 0.5 0.0 0.3 0.2 0.2 0.2 0.2 0.1 0.1 0.3 0.4 0.5 0.5 0.4 0.3 0.3 1.2 0.4 0.5 0.5 0.6 0.8 2.3 0.0 0.0 0.0 0.7 0.3 3.4 0.1 18.2 0.4 0.6 1.3 0.0 0.0 0.0 1.8 0.0 0.2 1.2 0.5 0.0 0.2 0.0 1.9 0.2 1.6 1.8 2.1 0.0 1.4 0.1 0.5 1.5 0.4 0.0 0.2 1.1 1.0 0.7 3.3 0.0 0.4 0.0 1.9 0.0 0.0 0.3 1.8 0.0 0.0 0.2 0.2 1.0 0.0 0.0 0.4 1.2 0.0 3.0 0.4 1.1 0.3 0.7 0.5 0.0 0.3 0.2 0.9 0.2 15.7 0.1 0.3 2.3 0.3 0.8 0.8 LY6K "CT97, FLJ35226, HSJ001348" ENSG00000160886 "Lymphocyte antigen 6 family member K" Q17RY6 8 142700111-142705127 "Predicted membrane proteins, Predicted secreted proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 12.5;testis: 36.0" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 186.7;Prostatic glandular cells: 105.2;Spermatocytes: 404.4;Spermatogonia: 105.8;Urothelial cells: 131.4" "Cancer enhanced" "Detected in many" "cervical cancer: 11.0" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "neutrophil: 1.8" "Lineage enriched" "Detected in single" 14 "granulocytes: 1.8" "Cell line enhanced" "Detected in many" "A-431: 125.2;BJ: 131.9;HeLa: 142.4;SiHa: 206.3;U-2197: 273.2" "Not detected" "Not detected" "Not detected" "Not detected" "HPA017770, CAB075742, CAB075743, CAB079929" Enhanced Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 71: Testis - DNA repair" "Cluster 18: U-2197 - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB075742: AB_2665748, CAB075743: AB_2665749, CAB079929: , HPA017770: AB_1853414" "unprognostic (1.25e-1)" "unprognostic (1.95e-2)" "unprognostic (1.48e-1)" "unprognostic (7.23e-3)" "unprognostic (3.47e-2)" "unprognostic (2.39e-1)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.17e-5)" "unprognostic (4.18e-2)" "unprognostic (6.89e-2)" "unprognostic (9.75e-2)" "unprognostic (1.40e-1)" "unprognostic (5.27e-5)" "unprognostic (1.71e-1)" "unprognostic (1.46e-1)" "unprognostic (2.03e-1)" "unprognostic (4.61e-2)" 5.4 0.2 0.6 0.2 0.6 0.3 4.4 0.9 1.7 3.3 0.0 0.5 0.3 0.5 0.2 12.5 1.2 0.4 1.5 0.8 1.0 3.0 0.2 0.8 0.2 1.7 0.8 0.7 0.3 0.0 0.4 2.4 2.0 1.1 0.0 2.4 1.7 0.8 5.4 6.8 0.3 0.1 1.1 0.2 1.1 36.0 0.7 0.6 1.0 1.3 0.6 1.0 5.1 1.1 125.2 2.0 0.0 6.3 2.4 7.9 1.5 131.9 15.3 39.9 24.0 0.2 0.5 0.0 10.9 15.0 14.3 10.8 0.0 7.5 33.5 1.2 0.2 0.1 142.4 0.3 1.9 0.0 0.0 11.7 21.1 29.7 38.0 0.1 3.7 0.0 0.0 0.6 76.2 1.0 0.2 0.3 4.2 4.1 2.0 0.3 0.5 0.2 6.7 1.7 3.7 0.5 206.3 2.7 41.3 6.6 0.5 0.2 5.4 1.9 11.8 273.2 0.2 0.2 0.1 0.3 0.6 0.1 13.6 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 0.1 0.0 0.0 0.0 0.0 0.6 0.6 0.9 1.7 0.8 1.0 1.7 0.8 2.0 1.1 0.7 1.1 25.6 3.2 0.5 0.0 0.4 38.9 54.2 4.3 21.6 0.6 15.1 49.8 0.2 5.7 9.8 25.8 0.0 13.5 0.3 0.0 0.0 0.8 7.7 3.1 8.5 9.2 0.0 0.0 0.0 0.0 186.7 8.0 0.0 9.0 0.0 0.0 3.3 0.1 6.0 0.0 0.0 0.0 6.1 0.3 28.7 14.8 4.1 4.6 12.4 0.0 0.0 0.5 0.0 0.0 0.1 6.7 1.1 3.0 0.0 105.2 0.0 0.2 3.6 0.6 0.0 17.8 13.1 404.4 105.8 32.2 44.9 25.3 0.7 0.1 0.0 131.4 LY9 "CD229, hly9, mLY9, SLAMF3" ENSG00000122224 "Lymphocyte antigen 9" Q9HBG7 1 160796074-160828261 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Adaptive immunity, Cell adhesion, Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 11.5;intestine: 12.0;lymphoid tissue: 31.1" "Cell type enhanced" "Detected in some" "B-cells: 244.0;dendritic cells: 36.2;Melanocytes: 71.2;Plasma cells: 102.5;T-cells: 44.8" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 112.9;MAIT T-cell: 113.5;memory B-cell: 56.1;memory CD4 T-cell: 97.6;memory CD8 T-cell: 109.8;naive B-cell: 52.8;naive CD4 T-cell: 109.6;naive CD8 T-cell: 112.3;plasmacytoid DC: 72.8;T-reg: 80.3" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 14.3;JURKAT: 14.1;Karpas-707: 28.0;U-266/70: 70.7;U-266/84: 29.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA050917 Approved Approved "Plasma membrane,Centriolar satellite" NA NA 43000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 29: U-266 - Adaptive immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Centriolar satellite" "HPA050917: AB_2681272" "unprognostic (8.04e-4)" "unprognostic (2.31e-5)" "unprognostic (8.08e-3)" "unprognostic (1.20e-3)" "unprognostic (9.83e-3)" "unprognostic (1.87e-5)" "unprognostic (1.16e-2)" "unprognostic (3.84e-3)" "unprognostic (1.23e-2)" "unprognostic (2.89e-3)" "unprognostic (1.64e-1)" "unprognostic (2.30e-1)" "unprognostic (2.70e-3)" "unprognostic (8.69e-2)" "unprognostic (9.47e-2)" "unprognostic (3.49e-2)" "unprognostic (6.88e-2)" 2.4 0.9 0.1 13.7 0.2 11.5 2.0 0.1 0.2 0.8 0.2 3.9 4.0 0.6 0.4 0.9 0.9 2.5 0.5 0.1 0.2 1.1 2.3 3.8 30.2 0.3 0.2 0.6 0.2 0.0 0.2 0.3 0.2 1.1 3.8 0.0 7.1 0.4 0.3 0.8 12.0 0.5 0.3 26.7 6.0 0.2 0.2 25.5 1.4 0.2 31.1 3.5 0.9 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 14.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 14.1 0.0 28.0 0.0 0.0 2.3 0.5 0.1 0.8 0.0 1.6 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 70.7 29.3 0.3 0.0 4.0 0.0 1.2 0.8 0.4 112.9 1.1 113.5 56.1 97.6 109.8 5.2 52.8 109.6 112.3 2.4 22.2 0.8 72.8 80.3 53.5 0.1 0.2 0.1 0.2 0.1 0.2 0.3 0.2 0.2 0.3 0.2 0.2 0.4 0.0 1.8 0.3 244.0 1.0 0.5 0.1 0.0 0.0 0.4 0.8 0.9 0.0 0.0 0.0 0.0 0.1 36.2 0.1 0.0 0.0 0.1 0.1 0.1 0.7 1.2 28.0 0.1 0.2 0.0 1.4 0.5 0.1 0.0 0.0 1.8 0.4 1.9 0.0 0.1 0.0 0.0 3.2 31.9 0.0 0.0 6.3 71.2 1.9 2.1 0.0 22.6 0.0 0.1 0.1 0.0 0.0 102.5 0.2 0.0 0.3 0.0 0.0 0.0 0.5 0.6 0.0 0.1 0.5 1.0 0.1 44.8 0.0 0.3 0.3 LZTS1 FEZ1 ENSG00000061337 "Leucine zipper tumor suppressor 1" Q9Y250 8 20246165-20303963 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle" "Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 14.8;parathyroid gland: 54.2" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 17.6;Excitatory neurons: 26.2;Horizontal cells: 20.2;Melanocytes: 19.6;Rod photoreceptor cells: 18.5;Sertoli cells: 65.7;Smooth muscle cells: 15.4" "Cancer enhanced" "Detected in all" "melanoma: 59.2" "Group enriched" "Detected in many" 5 "amygdala: 13.1;basal ganglia: 11.6;cerebral cortex: 14.8;hippocampal formation: 14.5;white matter: 9.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MOLT-4: 19.7;SK-MEL-30: 75.0;U-698: 23.2;WM-115: 50.8" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 10 "amygdala: 23.2;basal ganglia: 66.8;cerebral cortex: 45.5;hippocampal formation: 36.3;olfactory bulb: 26.7" "HPA006294, HPA022046" Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane" Nucleoli "HPA006294: AB_1079288, HPA022046: AB_1853455" "unprognostic (7.76e-2)" "unprognostic (1.02e-1)" "unprognostic (3.49e-3)" "prognostic unfavorable (3.03e-4)" "unprognostic (6.27e-2)" "unprognostic (1.96e-1)" "unprognostic (7.29e-2)" "unprognostic (5.76e-2)" "unprognostic (1.41e-2)" "unprognostic (9.06e-3)" "unprognostic (6.81e-2)" "unprognostic (3.63e-2)" "prognostic unfavorable (9.28e-6)" "unprognostic (3.35e-2)" "unprognostic (2.71e-1)" "unprognostic (1.11e-1)" "unprognostic (6.82e-3)" 3.7 1.7 13.1 1.5 11.6 0.1 3.0 0.0 14.8 2.0 0.0 1.3 0.5 2.9 0.9 5.3 1.6 3.5 5.0 14.5 0.6 4.7 0.7 7.0 1.1 0.0 0.1 1.2 1.5 54.2 2.2 6.5 0.3 2.8 0.4 3.5 1.4 1.1 1.9 4.6 0.9 2.5 0.0 0.5 1.4 7.5 2.3 1.9 2.7 2.0 0.5 2.3 1.7 9.2 0.1 0.0 9.7 8.3 0.0 0.0 1.2 5.0 0.1 4.3 3.7 0.3 0.1 11.1 3.5 3.1 1.6 0.2 0.5 0.2 2.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 1.7 0.9 0.1 1.8 0.0 0.6 0.0 11.7 0.0 0.1 14.4 0.0 19.7 0.1 12.2 0.0 0.0 0.0 15.6 0.0 2.7 0.4 14.8 12.9 0.0 0.0 75.0 8.2 0.1 0.4 0.0 5.1 3.5 0.1 1.5 0.1 0.1 23.2 0.1 1.1 50.8 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 13.1 11.6 0.0 14.8 14.5 0.6 0.0 0.1 0.3 0.0 2.3 9.2 3.9 0.0 0.0 1.6 0.0 1.3 0.8 1.0 17.6 1.8 0.3 11.3 4.6 0.0 0.1 0.0 4.2 7.1 0.4 0.0 1.9 0.0 0.5 0.6 1.3 3.2 0.0 0.0 26.2 0.0 2.3 2.4 0.0 0.5 0.0 3.5 0.0 0.0 0.9 20.2 2.9 0.0 2.0 0.0 0.0 0.8 1.2 0.2 19.6 1.9 0.0 0.9 0.0 6.0 0.8 0.0 0.0 0.4 0.0 0.1 0.0 0.4 0.0 18.5 65.7 1.1 15.4 0.2 1.1 7.3 0.1 0.8 1.4 2.5 0.0 0.0 LZTS2 "KIAA1813, LAPSER1" ENSG00000107816 "Leucine zipper tumor suppressor 2" Q9BRK4 10 100996618-101007836 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 70.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044956 Approved Approved "Plasma membrane,Cytosol" No Yes "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA044956: AB_10795989" "unprognostic (1.42e-2)" "unprognostic (1.96e-1)" "prognostic unfavorable (8.23e-4)" "unprognostic (8.18e-2)" "unprognostic (4.64e-2)" "unprognostic (1.56e-1)" "unprognostic (5.49e-3)" "unprognostic (3.56e-1)" "unprognostic (7.57e-2)" "unprognostic (4.58e-2)" "unprognostic (2.72e-1)" "unprognostic (1.38e-1)" "prognostic unfavorable (3.39e-4)" "unprognostic (7.63e-2)" "unprognostic (1.86e-1)" "unprognostic (5.46e-3)" "unprognostic (1.76e-3)" 69.9 66.0 46.8 14.9 65.5 14.4 63.3 58.0 54.1 74.3 25.8 96.3 17.5 90.3 17.7 41.0 69.2 19.8 58.9 41.2 45.8 51.8 18.0 57.1 12.1 63.7 64.3 78.6 29.5 29.1 43.6 28.5 58.5 69.5 8.9 5.9 44.3 40.6 37.8 48.9 43.0 26.6 49.0 44.4 54.9 36.2 64.1 10.8 57.6 18.0 8.1 84.1 54.4 78.9 32.9 43.1 34.6 59.7 45.0 36.3 70.8 38.7 72.8 31.9 36.0 50.5 26.6 13.1 35.1 52.5 23.0 54.6 21.5 28.2 7.8 12.8 31.9 12.1 46.4 66.3 63.6 6.4 15.2 66.1 20.2 25.1 30.1 67.3 32.8 15.6 38.7 7.3 28.7 31.6 5.8 15.8 38.8 12.6 35.2 74.7 101.3 13.5 24.4 39.3 8.4 62.8 26.3 11.9 99.9 18.6 61.0 51.6 42.1 37.9 42.6 40.5 20.7 14.0 10.2 3.3 64.0 17.7 19.4 0.0 0.7 0.4 2.7 0.4 3.7 2.3 3.4 3.0 1.1 2.9 3.5 3.0 0.3 2.9 0.1 1.8 3.0 1.5 46.8 65.5 58.0 54.1 41.2 45.8 63.7 64.3 58.5 49.0 64.1 78.9 34.7 16.0 10.5 20.2 5.3 13.4 9.0 12.4 19.4 14.4 21.7 20.3 5.2 11.5 9.4 5.5 6.2 18.6 1.9 8.0 7.9 19.1 6.8 7.9 20.5 22.9 16.7 5.0 6.8 12.6 13.2 21.8 14.8 13.0 1.3 38.9 18.5 2.6 22.2 18.5 7.7 17.8 16.2 7.2 9.2 4.1 25.7 8.4 16.0 13.1 4.8 18.9 4.1 9.0 70.3 13.3 7.9 29.3 5.4 18.1 6.5 8.3 6.1 4.0 26.3 21.1 40.7 3.8 15.0 10.8 12.1 47.1 6.0 26.9 15.1 9.7 MADD "DENN, KIAA0358, RAB3GEP" ENSG00000110514 "MAP kinase activating death domain" Q8WXG6 11 47269161-47330031 "Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Guanine-nucleotide releasing factor" "Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 133.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 80.9;Cone photoreceptor cells: 125.1;Horizontal cells: 132.9;Rod photoreceptor cells: 106.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "basophil: 33.3" "Lineage enriched" "Detected in all" 4 "granulocytes: 33.3" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038568 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 15: RT4 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA038568: AB_10795030" "unprognostic (3.16e-1)" "unprognostic (1.81e-1)" "unprognostic (8.51e-3)" "prognostic favorable (6.62e-5)" "unprognostic (1.27e-1)" "unprognostic (6.36e-3)" "unprognostic (4.82e-3)" "unprognostic (1.16e-1)" "unprognostic (1.91e-1)" "unprognostic (3.78e-2)" "prognostic favorable (5.69e-5)" "unprognostic (1.53e-1)" "unprognostic (3.55e-1)" "unprognostic (8.07e-2)" "unprognostic (1.06e-1)" "unprognostic (2.76e-1)" "prognostic favorable (8.25e-4)" 15.1 24.6 32.4 17.7 32.2 28.4 14.8 46.7 44.5 16.1 0.3 17.9 12.4 15.1 12.0 11.1 14.0 12.2 24.6 40.5 21.2 17.1 13.0 19.0 20.9 18.2 18.8 18.8 17.5 18.4 65.7 16.0 22.1 20.7 16.6 133.2 16.6 17.1 30.1 22.8 19.0 14.6 7.0 22.0 18.8 28.5 16.7 23.6 14.4 23.4 17.9 18.7 15.0 32.1 14.0 28.7 30.8 27.6 20.6 14.3 6.9 19.3 25.8 24.2 25.9 21.0 12.9 29.6 6.0 21.3 31.1 27.2 25.2 13.6 20.8 33.1 25.6 52.7 55.0 18.3 14.8 36.1 69.4 13.9 14.3 12.7 15.9 16.4 22.4 18.7 34.5 21.1 21.5 19.7 17.2 38.6 18.4 32.8 19.6 23.2 49.5 19.7 12.4 66.0 48.4 31.5 24.9 29.0 17.6 18.1 22.8 27.0 19.2 22.4 14.1 32.3 13.2 24.9 27.9 16.6 20.9 25.1 21.5 33.3 3.4 6.5 5.6 5.6 5.0 4.0 3.9 4.6 5.2 4.2 4.5 3.6 0.9 5.7 7.9 2.7 7.5 6.2 32.4 32.2 46.7 44.5 40.5 21.2 18.2 18.8 22.1 7.0 16.7 32.1 10.6 12.8 9.2 21.5 11.7 10.7 4.1 6.1 6.8 80.9 11.3 10.2 23.4 7.2 5.8 7.3 125.1 4.6 29.0 21.2 0.0 7.5 14.6 5.3 7.0 11.5 16.3 8.6 37.4 4.9 2.3 7.8 23.4 8.3 26.6 13.9 14.6 7.0 11.5 132.9 33.7 17.7 4.1 19.4 14.9 4.9 7.2 14.9 10.6 21.5 11.1 14.4 23.7 14.1 22.4 12.0 12.2 12.8 17.7 8.0 12.2 5.1 6.2 106.8 6.6 8.7 7.7 14.9 23.2 6.7 8.2 4.4 15.4 16.2 13.7 5.9 MAMDC2 MGC21981 ENSG00000165072 "MAM domain containing 2" Q7Z304 9 70043848-70226972 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 74.5" "Cell type enhanced" "Detected in many" "Early spermatids: 42.5;Excitatory neurons: 37.0;Fibroblasts: 38.7;Inhibitory neurons: 42.9;Leydig cells: 96.6;Microglial cells: 45.9;Peritubular cells: 82.0;Sertoli cells: 39.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 55.7;HHSteC: 57.2;LHCN-M2: 75.0;TIME: 71.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA021814, HPA022249" Uncertain Approved "Nuclear speckles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 4: Macrophages - Innate immune response" "Nuclear speckles, Plasma membrane" "HPA021814: AB_1853508, HPA022249: AB_2139157" "unprognostic (1.88e-1)" "unprognostic (3.16e-3)" "unprognostic (2.21e-3)" "unprognostic (2.71e-2)" "unprognostic (4.30e-2)" "unprognostic (8.49e-2)" "unprognostic (1.27e-2)" "unprognostic (8.25e-2)" "unprognostic (5.91e-2)" "unprognostic (3.65e-2)" "unprognostic (1.92e-1)" "unprognostic (3.67e-1)" "unprognostic (3.03e-2)" "unprognostic (4.23e-3)" "unprognostic (2.35e-1)" "prognostic unfavorable (7.78e-4)" "unprognostic (2.79e-3)" 17.2 8.2 1.0 1.2 1.2 0.2 15.6 0.8 1.6 30.4 2.3 45.5 8.4 74.5 19.1 21.2 58.5 13.0 15.4 0.7 1.5 2.6 1.2 37.2 0.5 0.7 1.2 49.1 3.7 1.8 0.8 4.3 0.7 7.7 12.3 5.7 9.9 10.8 6.6 9.2 21.6 25.3 0.7 16.1 19.1 7.5 1.8 1.6 8.0 17.1 3.1 32.3 18.5 1.1 0.3 0.0 0.7 0.0 55.7 18.8 1.7 11.1 5.0 2.7 4.6 0.0 1.2 0.0 0.7 2.1 1.5 9.1 0.1 0.8 2.3 0.0 0.0 0.0 15.6 0.1 57.2 0.0 0.0 3.6 0.7 1.7 0.9 19.9 4.9 0.0 0.0 0.5 75.0 0.0 0.0 0.1 7.7 0.1 0.0 0.0 8.8 7.3 24.6 0.0 0.7 0.0 0.1 0.1 0.0 20.8 0.0 0.0 71.0 0.0 1.8 0.1 2.1 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 1.0 1.2 0.8 1.6 0.7 1.5 0.7 1.2 0.7 0.7 1.8 1.1 2.0 0.0 1.5 20.2 0.5 6.1 0.5 0.4 0.6 0.8 0.5 10.8 4.3 0.0 0.1 3.7 4.2 0.2 0.2 0.2 0.0 0.1 42.5 0.7 13.7 3.9 0.0 0.0 37.0 0.2 6.6 38.7 0.5 0.5 1.3 0.3 0.4 0.0 3.3 0.0 42.9 0.1 0.0 0.0 17.5 11.4 96.6 13.6 10.6 45.9 0.0 13.8 0.0 11.6 23.3 0.4 0.2 82.0 0.0 0.1 0.0 0.5 0.1 0.5 39.5 4.8 22.4 0.4 0.4 1.1 4.8 0.3 0.8 0.1 0.1 0.1 MAP2 "MAP2A, MAP2B, MAP2C" ENSG00000078018 "Microtubule associated protein 2" P11137 2 209424058-209734118 "FDA approved drug targets, Plasma proteins, Predicted intracellular proteins" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 10 "brain: 253.3;retina: 411.0" "Group enriched" "Detected in many" 5 "Cone photoreceptor cells: 875.7;Excitatory neurons: 883.3;Inhibitory neurons: 823.6;Oligodendrocyte precursor cells: 688.6;Rod photoreceptor cells: 514.5" "Group enriched" "Detected in many" 4 "glioma: 30.4;thyroid cancer: 8.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 296.9;NTERA-2: 106.7;SCLC-21H: 148.6;SH-SY5Y: 82.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB001984, HPA008273, HPA012558, HPA012828" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 58: Brain - Synaptic function" "Cluster 12: NES - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "CAB001984: , HPA008273: AB_1853945, HPA012558: , HPA012828: AB_1853946" "unprognostic (2.47e-2)" "unprognostic (2.81e-1)" "unprognostic (2.58e-2)" "prognostic unfavorable (1.98e-6)" "unprognostic (2.29e-2)" "unprognostic (1.79e-1)" "unprognostic (1.13e-2)" "unprognostic (6.06e-2)" "unprognostic (1.31e-1)" "unprognostic (9.84e-2)" "unprognostic (1.09e-2)" "unprognostic (1.60e-1)" "unprognostic (1.23e-1)" "unprognostic (2.69e-3)" "unprognostic (2.54e-1)" "unprognostic (7.28e-2)" "unprognostic (4.10e-5)" 5.5 11.6 89.2 1.2 115.9 0.3 5.5 2.7 253.3 4.3 0.0 2.9 0.9 2.3 3.9 6.5 2.5 7.6 8.4 135.2 215.6 5.4 3.8 13.5 1.8 37.7 52.2 7.4 10.7 15.5 33.8 0.8 75.3 7.6 1.7 411.0 7.8 4.9 1.7 16.9 1.6 2.8 14.5 1.7 3.3 6.5 123.9 3.5 16.7 4.6 2.4 1.6 5.3 88.2 2.6 0.6 296.9 0.0 3.9 2.2 0.1 1.9 2.1 0.7 2.2 0.0 16.1 0.0 1.7 3.8 14.0 4.1 23.4 1.8 1.0 0.1 1.4 1.2 8.9 0.1 36.7 0.3 0.2 3.1 9.6 0.1 5.8 17.3 7.8 0.1 0.0 3.1 0.3 1.1 0.1 0.0 106.7 0.5 0.5 0.0 0.6 0.3 3.8 0.1 148.6 82.7 6.3 0.9 3.7 34.8 8.2 0.0 0.2 0.3 1.7 0.1 4.1 1.9 0.0 0.0 15.5 0.0 45.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 89.2 115.9 2.7 253.3 135.2 215.6 37.7 52.2 75.3 14.5 123.9 88.2 16.8 96.1 3.2 127.3 1.8 5.9 3.3 12.0 4.6 144.7 6.2 8.0 4.9 27.1 3.7 5.5 875.7 0.4 0.1 0.0 3.9 26.8 22.1 2.2 1.1 15.7 32.4 2.7 883.3 11.0 0.1 5.3 3.6 4.4 1.3 1.6 18.5 0.4 0.5 33.7 823.6 0.2 6.1 1.4 1.5 10.7 28.6 1.4 19.6 74.0 0.0 129.7 0.0 688.6 53.8 10.0 0.0 15.4 0.1 12.3 0.0 0.4 3.4 514.5 32.9 5.1 26.1 6.6 22.7 2.3 6.5 0.3 0.3 6.6 0.0 0.7 MAP2K1 "MAPKK1, MEK1, PRKMK1" ENSG00000169032 "Mitogen-activated protein kinase kinase 1" Q02750 15 66386837-66491544 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Cardiomyopathy, Disease variant, Ectodermal dysplasia, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 172.5;Langerhans cells: 265.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003834, HPA026430" Approved Enhanced "Plasma membrane,Cytosol" NA NA 120000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB003834: AB_562310, HPA026430: AB_1853742" "unprognostic (4.05e-2)" "unprognostic (1.23e-2)" "unprognostic (2.07e-1)" "unprognostic (4.92e-2)" "prognostic unfavorable (1.95e-4)" "unprognostic (1.81e-3)" "unprognostic (5.78e-2)" "unprognostic (9.91e-3)" "unprognostic (1.11e-1)" "unprognostic (1.77e-1)" "unprognostic (1.45e-1)" "unprognostic (7.62e-3)" "unprognostic (1.20e-1)" "unprognostic (2.71e-1)" "unprognostic (1.96e-1)" "unprognostic (1.15e-1)" "unprognostic (9.40e-3)" 57.9 31.0 47.6 38.3 79.7 63.7 32.5 30.2 61.3 31.1 22.5 26.5 19.4 26.3 29.6 51.8 23.7 27.0 40.7 69.4 44.3 31.2 105.3 34.7 49.5 31.6 32.6 25.7 22.4 38.5 26.8 29.6 40.1 26.2 23.6 34.1 29.3 21.8 85.5 23.7 27.0 31.9 35.7 32.6 24.1 15.2 42.8 33.8 22.8 51.3 55.4 31.2 33.7 49.9 105.8 55.3 94.4 39.0 55.3 41.3 53.8 83.6 61.6 76.6 68.1 79.0 82.1 96.8 93.2 59.9 58.2 93.3 88.8 106.4 89.8 79.1 56.8 30.9 50.4 40.7 45.1 41.0 45.3 32.3 64.0 55.9 81.6 81.5 60.7 48.0 54.3 116.7 113.4 40.3 33.5 51.9 47.9 93.9 42.9 39.2 58.1 84.7 74.8 48.5 58.3 31.7 60.8 45.5 63.0 74.9 41.0 33.7 90.8 99.5 63.8 71.1 112.4 74.0 143.1 60.6 105.1 69.9 48.4 3.0 7.5 5.4 6.4 7.7 5.8 2.8 5.6 6.1 7.7 4.6 6.9 4.2 3.5 8.3 7.7 15.1 4.6 2.8 47.6 79.7 30.2 61.3 69.4 44.3 31.6 32.6 40.1 35.7 42.8 49.9 24.5 28.9 24.8 24.2 40.0 82.8 45.9 32.3 21.1 10.0 22.2 10.2 21.5 40.0 24.9 25.8 14.6 48.1 45.0 25.1 46.9 69.4 12.1 16.3 13.9 34.6 21.7 19.0 69.7 23.1 48.8 30.3 17.9 35.4 8.9 19.8 18.9 172.5 51.4 10.1 46.4 15.4 20.3 90.7 265.3 23.6 22.4 115.1 53.4 48.7 87.9 34.9 35.0 28.1 31.7 103.9 23.5 21.8 49.1 87.7 22.2 35.9 17.7 7.8 6.6 16.3 52.4 35.6 42.7 30.3 67.3 51.7 54.0 5.9 19.1 65.4 MAP3K12 "DLK, MEKK12, MUK, ZPK, ZPKP1" ENSG00000139625 "Mitogen-activated protein kinase kinase kinase 12" Q12852 12 53479669-53500063 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Rod photoreceptor cells: 85.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 55.9;HHSteC: 53.7;HSkMC: 51.8;hTERT-RPE1: 69.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039936, HPA071996" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 35: Non-specific - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 46: Photoreceptor cells - Phototransduction" "Nucleoplasm, Plasma membrane" "HPA039936: AB_10795239, HPA071996: AB_2686481" "unprognostic (4.01e-1)" "unprognostic (3.30e-1)" "unprognostic (8.89e-3)" "unprognostic (6.40e-3)" "unprognostic (1.10e-1)" "unprognostic (2.22e-1)" "unprognostic (6.97e-2)" "unprognostic (3.61e-2)" "unprognostic (2.39e-1)" "unprognostic (2.70e-1)" "prognostic favorable (1.51e-4)" "unprognostic (8.50e-3)" "prognostic unfavorable (5.43e-10)" "unprognostic (1.65e-2)" "unprognostic (2.44e-1)" "unprognostic (1.32e-1)" "unprognostic (1.18e-1)" 12.6 7.6 12.9 5.4 15.2 3.2 10.3 25.9 19.6 23.5 4.3 13.3 3.2 22.9 4.8 4.0 18.5 14.0 8.6 15.6 11.3 8.5 1.7 11.2 4.4 11.9 11.1 21.6 3.6 7.3 22.7 6.4 13.2 9.6 3.8 13.6 4.9 10.9 2.7 5.7 8.9 14.4 8.0 9.0 7.3 9.0 13.0 6.0 8.6 6.3 2.7 14.0 12.2 13.7 0.5 15.1 8.6 14.2 55.9 28.9 1.2 10.1 18.9 10.8 11.0 0.3 1.8 3.5 5.4 10.8 8.7 0.1 4.3 6.8 4.3 4.9 5.4 3.5 8.3 0.0 53.7 0.1 3.6 51.8 5.2 14.6 7.8 69.1 16.9 7.8 0.1 15.7 10.0 6.7 3.8 0.9 3.2 0.0 5.5 5.4 6.3 1.0 5.4 0.1 9.3 12.4 5.6 6.8 14.9 1.8 4.6 10.3 12.9 10.2 10.8 4.5 2.5 6.1 8.0 0.0 16.8 6.9 10.4 0.0 0.5 0.0 0.4 0.4 0.8 0.1 0.5 0.6 0.2 0.0 0.2 0.3 1.0 0.2 0.1 0.0 0.1 0.1 12.9 15.2 25.9 19.6 15.6 11.3 11.9 11.1 13.2 8.0 13.0 13.7 11.4 6.4 14.6 21.5 8.1 0.8 2.4 0.5 4.6 28.9 5.6 5.2 0.8 7.2 6.4 1.8 37.5 1.9 12.2 4.8 9.8 6.7 1.5 11.5 27.6 10.4 3.5 1.3 21.1 1.8 2.2 11.0 2.0 15.8 12.7 7.0 15.0 7.8 4.1 30.3 19.1 2.8 2.0 10.3 2.2 1.8 8.1 8.6 0.0 8.4 8.5 19.9 5.2 10.6 11.0 4.4 2.1 8.2 6.7 5.3 7.1 14.8 5.5 85.0 6.6 23.5 10.2 2.5 2.1 2.5 1.0 2.2 11.6 12.5 4.1 3.9 MAP3K21 "KIAA1804, MLK4" ENSG00000143674 "Mitogen-activated protein kinase kinase kinase 21" Q5TCX8 1 233327724-233385148 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pancreas: 20.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 35.3;Alveolar cells type 2: 10.0;Collecting duct cells: 14.7;Ductal cells: 11.9;Exocrine glandular cells: 9.8;Glandular and luminal cells: 11.7;Proximal tubular cells: 12.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 5 "NK-cell: 1.5" "Lineage enriched" "Detected in single" 5 "NK-cells: 1.5" "Cell line enhanced" "Detected in many" "HEK 293: 27.4" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" HPA007636 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA007636: AB_1079392" "unprognostic (3.29e-2)" "unprognostic (5.10e-2)" "unprognostic (2.00e-1)" "unprognostic (2.42e-3)" "unprognostic (4.30e-2)" "unprognostic (1.23e-1)" "unprognostic (1.82e-2)" "unprognostic (1.84e-1)" "unprognostic (1.51e-1)" "unprognostic (1.25e-1)" "unprognostic (2.09e-1)" "unprognostic (8.21e-2)" "unprognostic (3.76e-2)" "unprognostic (2.23e-1)" "unprognostic (1.71e-1)" "unprognostic (9.22e-2)" "unprognostic (4.84e-2)" 0.7 3.8 1.8 1.3 1.6 2.1 2.5 5.2 2.4 1.0 0.7 6.3 11.7 1.2 3.3 2.5 4.6 1.7 0.4 1.4 1.4 13.5 5.4 4.5 0.9 1.5 0.3 0.7 20.3 4.3 2.1 0.3 1.7 1.3 6.9 1.0 3.8 2.7 0.0 3.3 10.1 0.6 0.2 0.5 12.4 9.4 1.8 0.4 2.3 0.0 1.3 1.2 1.8 1.3 11.6 19.4 0.4 0.0 0.0 0.0 9.6 0.3 0.0 0.4 0.8 10.8 9.8 1.1 7.7 0.2 3.6 6.0 14.4 5.9 1.2 21.6 27.4 0.1 11.4 0.0 0.7 19.0 4.3 0.2 7.8 0.3 10.9 2.2 0.7 8.7 0.2 3.7 0.0 2.6 6.1 6.8 13.6 13.4 8.4 0.0 0.0 20.7 13.1 4.8 13.9 3.7 6.6 0.3 0.0 1.5 5.6 6.0 0.0 0.0 1.8 0.1 11.5 3.4 4.6 0.0 1.8 5.1 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 1.8 1.6 5.2 2.4 1.4 1.4 1.5 0.3 1.7 0.2 1.8 1.3 0.9 35.3 10.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 7.0 6.5 0.0 0.0 0.6 14.7 0.0 0.0 0.4 0.0 3.9 11.9 0.0 5.7 1.0 0.3 0.0 0.0 0.0 9.8 0.0 0.5 0.0 11.7 0.0 2.5 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 1.0 0.0 0.0 0.0 0.0 7.6 0.0 0.0 0.7 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 MAP4K5 "GCKR, KHS, KHS1" ENSG00000012983 "Mitogen-activated protein kinase kinase kinase kinase 5" Q9Y4K4 14 50418501-50561126 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocyte precursor cells: 332.7;Oligodendrocytes: 707.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 5 "basophil: 66.7;eosinophil: 26.3" "Lineage enriched" "Detected in all" 7 "granulocytes: 66.7" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA036696, HPA078030" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 42: Oligodendrocytes - Myelin sheath organization" Cytosol "Plasma membrane" "HPA036696: AB_10672362, HPA078030: " "unprognostic (1.39e-1)" "unprognostic (1.00e-1)" "unprognostic (3.80e-1)" "unprognostic (1.66e-1)" "unprognostic (4.41e-2)" "unprognostic (1.43e-1)" "unprognostic (8.58e-3)" "unprognostic (4.13e-2)" "unprognostic (6.31e-2)" "unprognostic (2.24e-2)" "unprognostic (1.53e-3)" "unprognostic (7.34e-2)" "unprognostic (1.78e-2)" "unprognostic (3.71e-2)" "unprognostic (1.40e-1)" "unprognostic (9.58e-3)" "unprognostic (2.02e-2)" 20.5 12.8 16.2 13.2 31.1 22.1 22.2 20.7 21.5 30.6 3.9 20.8 13.1 33.4 12.9 20.5 19.0 21.5 10.9 18.3 23.9 11.9 10.0 17.1 12.4 28.4 22.0 32.4 14.2 14.8 11.8 19.8 24.8 17.9 16.6 18.6 18.0 21.1 12.3 28.5 14.7 24.7 17.6 15.7 16.8 7.9 23.8 11.6 17.0 14.2 13.2 20.2 23.8 58.1 51.7 15.2 36.5 31.5 33.0 34.5 35.6 59.2 53.0 39.4 34.9 19.3 35.2 35.3 34.3 54.6 20.9 36.1 34.3 31.9 59.7 29.4 24.8 21.7 27.1 17.5 27.9 19.6 33.0 25.2 25.7 34.8 36.1 63.0 52.6 31.7 20.8 22.5 58.6 19.4 26.6 18.7 17.7 16.6 29.5 31.8 55.4 13.5 39.2 39.5 11.7 26.5 33.5 23.0 23.4 29.3 25.8 14.7 53.8 50.9 35.7 35.2 28.2 16.3 18.0 23.6 19.2 13.5 37.2 66.7 2.8 26.3 6.7 3.3 3.8 6.1 4.2 5.9 3.0 9.7 4.4 4.6 1.0 10.1 2.2 4.9 1.0 1.9 16.2 31.1 20.7 21.5 18.3 23.9 28.4 22.0 24.8 17.6 23.8 58.1 40.5 41.7 20.8 135.2 29.9 70.0 42.9 21.4 56.3 56.7 32.6 26.5 10.5 30.0 27.4 27.6 47.9 11.4 30.6 27.5 19.6 29.5 3.7 25.7 52.2 40.4 23.4 46.7 144.2 20.9 19.5 50.1 43.8 49.1 29.8 37.8 38.6 9.0 8.1 33.7 144.1 16.4 8.2 12.3 24.8 3.7 42.6 25.1 23.2 101.2 18.3 19.5 18.6 332.7 707.2 25.9 20.2 51.1 27.0 57.4 10.9 12.0 25.6 33.1 13.1 49.7 41.7 10.6 14.1 54.9 86.1 6.6 31.5 22.4 18.6 61.7 MAPT "DDPAC, FLJ31424, FTDP-17, MAPTL, MGC138549, MSTD, MTBT1, MTBT2, PPND, PPP1R103, tau" ENSG00000186868 "Microtubule associated protein tau" P10636 17 45894527-46028334 "Candidate cardiovascular disease genes, Disease related genes, FDA approved drug targets, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins" "Alzheimer disease, Disease variant, FDA approved drug targets, Neurodegeneration, Parkinsonism" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 67.7;skeletal muscle: 79.0" "Cell type enhanced" "Detected in many" "Astrocytes: 142.4;Bipolar cells: 314.4;Early spermatids: 199.9;Excitatory neurons: 189.2;Horizontal cells: 361.7;Inhibitory neurons: 153.7;Late spermatids: 416.6;Muller glia cells: 145.7;Oligodendrocytes: 163.8" "Cancer enhanced" "Detected in many" "breast cancer: 9.5;glioma: 13.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 1.7" "Low lineage specificity" "Detected in single" "Group enriched" "Detected in many" 5 "HDLM-2: 69.0;SCLC-21H: 21.1;T-47d: 34.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000151, HPA048895, HPA069524, HPA069570, CAB072344" Enhanced Supported "Nuclear speckles,Plasma membrane" "Secreted to blood" NA NA 7100 "Cluster 35: T-regs - Unknown function" "Cluster 47: Non-specific - Unknown function" "Cluster 44: HDLM-2 - Immune response" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Nuclear speckles" "CAB000151: , CAB072344: , HPA048895: AB_2680550, HPA069524: AB_2686145, HPA069570: AB_2686155" "unprognostic (1.78e-3)" "unprognostic (7.51e-2)" "unprognostic (3.71e-2)" "unprognostic (8.40e-5)" "unprognostic (1.40e-1)" "unprognostic (1.31e-2)" "unprognostic (4.06e-5)" "unprognostic (6.04e-2)" "unprognostic (2.19e-2)" "unprognostic (3.49e-2)" "unprognostic (3.88e-3)" "unprognostic (2.65e-1)" "unprognostic (1.72e-3)" "unprognostic (6.53e-2)" "unprognostic (3.43e-1)" "unprognostic (1.85e-2)" "unprognostic (5.47e-2)" 4.7 4.3 26.2 0.3 27.1 0.0 9.1 8.3 67.7 2.4 0.0 8.4 0.5 1.0 0.2 8.4 1.0 0.8 9.4 30.0 20.4 14.7 0.6 0.8 0.3 11.6 11.4 0.6 1.5 2.9 29.5 3.4 22.4 5.4 0.3 17.6 8.5 3.4 79.0 6.3 1.8 0.3 2.7 0.4 1.7 20.3 14.8 0.4 0.9 27.4 0.2 10.2 2.3 19.7 2.9 0.5 0.3 6.4 0.3 0.9 1.8 0.1 0.3 0.1 0.0 0.2 0.0 0.0 0.6 0.4 0.5 0.1 2.3 0.3 0.0 69.0 3.4 0.0 0.3 4.2 0.0 0.1 0.1 0.0 0.5 0.1 0.3 0.1 0.0 4.4 0.7 3.6 0.0 7.7 1.0 0.2 0.2 0.7 2.0 0.0 4.0 8.5 0.0 9.1 21.1 9.1 2.5 0.0 1.8 1.0 34.7 0.1 0.1 0.3 0.8 1.7 0.3 0.9 0.3 0.0 0.6 2.0 0.5 0.1 0.0 0.0 0.2 0.7 0.2 0.0 0.1 0.5 0.0 0.0 0.2 0.3 0.2 0.1 1.7 0.0 0.7 0.0 26.2 27.1 8.3 67.7 30.0 20.4 11.6 11.4 22.4 2.7 14.8 19.7 1.9 0.0 9.8 142.4 1.0 1.0 1.4 0.2 1.2 314.4 26.7 21.2 35.2 0.0 0.1 1.8 64.6 0.2 0.4 0.1 7.9 0.5 199.9 0.4 1.7 1.8 0.0 0.0 189.2 0.4 9.1 3.7 0.5 1.3 4.5 1.6 1.1 0.5 0.3 361.7 153.7 0.0 2.0 0.6 1.7 416.6 2.8 0.8 5.4 8.4 0.7 145.7 0.0 129.7 163.8 0.6 0.0 2.6 0.1 2.5 0.1 76.1 0.0 28.3 0.0 28.2 6.0 18.4 8.1 22.7 3.3 0.3 1.5 0.8 0.3 0.6 MARCHF10 "FLJ35757, MARCH-X, MARCH10, RNF190" ENSG00000173838 "Membrane associated ring-CH-type finger 10" Q8NA82 17 62701314-62808344 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 11 "testis: 137.6" "Not detected" "Not detected" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.5;EFO-21: 4.7;HSkMC: 2.1;SCLC-21H: 8.3" "Low region specificity" "Detected in single" "Low region specificity" "Detected in some" HPA023322 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA023322: AB_1856351" "unprognostic (2.79e-2)" "unprognostic (2.32e-1)" "unprognostic (9.60e-3)" "unprognostic (6.95e-2)" "unprognostic (1.21e-1)" "unprognostic (1.21e-1)" "unprognostic (1.03e-2)" "unprognostic (1.67e-1)" "unprognostic (1.39e-1)" "unprognostic (7.99e-4)" "unprognostic (3.16e-1)" "unprognostic (2.85e-3)" "unprognostic (1.38e-1)" "unprognostic (4.83e-2)" "unprognostic (9.37e-3)" "unprognostic (2.66e-1)" 0.1 0.2 1.3 0.2 1.6 0.0 0.1 1.2 0.9 1.4 10.5 1.1 0.0 0.4 7.5 0.1 12.8 0.1 0.1 1.1 1.3 1.5 0.0 2.7 0.0 3.6 5.0 0.1 0.2 0.3 12.7 0.0 2.6 0.6 0.0 0.1 0.3 0.1 0.0 0.2 0.4 0.0 3.6 0.1 0.4 137.6 1.3 0.2 0.1 0.0 0.0 0.1 0.2 2.0 0.1 0.0 0.1 0.0 0.0 0.1 2.5 1.1 0.1 0.8 0.2 0.0 0.0 0.0 4.7 0.3 0.1 0.0 0.0 0.2 0.9 0.0 0.0 0.8 0.6 0.0 1.0 0.0 0.0 2.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.6 1.0 0.1 0.0 0.2 0.0 0.1 0.0 0.0 0.1 0.7 0.0 8.3 0.0 0.0 0.5 0.0 0.3 0.1 0.0 0.0 0.0 0.4 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.9 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.1 0.4 0.0 0.1 0.0 0.0 0.2 0.1 1.3 1.6 1.2 0.9 1.1 1.3 3.6 5.0 2.6 3.6 1.3 2.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 MARCHF7 "AXOT, MARCH-VII, MARCH7, RNF177" ENSG00000136536 "Membrane associated ring-CH-type finger 7" Q9H992 2 159712457-159771027 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in some" "Adipocytes: 33.3;Cardiomyocytes: 88.4;Cytotrophoblasts: 36.2;dendritic cells: 28.2;Extravillous trophoblasts: 38.8;Hofbauer cells: 34.0;Syncytiotrophoblasts: 44.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014275, HPA022152" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 23: Testis - Cell cycle regulation" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA014275: AB_10599820, HPA022152: AB_10601107" "unprognostic (2.42e-1)" "unprognostic (2.24e-1)" "unprognostic (1.02e-2)" "unprognostic (1.92e-2)" "unprognostic (1.62e-2)" "unprognostic (2.10e-1)" "prognostic unfavorable (2.41e-4)" "unprognostic (2.46e-2)" "unprognostic (6.42e-2)" "unprognostic (3.44e-1)" "unprognostic (3.17e-2)" "unprognostic (3.53e-2)" "prognostic unfavorable (1.84e-4)" "unprognostic (1.41e-3)" "unprognostic (1.38e-1)" "unprognostic (2.57e-1)" "unprognostic (1.61e-1)" 38.3 30.0 16.4 37.9 21.7 43.2 48.2 32.3 21.5 38.6 25.1 33.2 30.0 45.0 34.2 67.3 37.5 38.1 48.9 15.8 16.1 32.8 40.1 38.2 47.9 17.4 17.1 47.5 22.3 36.6 22.7 46.9 17.7 38.1 36.9 37.9 26.9 36.3 55.2 38.6 30.0 50.6 14.9 45.1 33.5 62.0 17.1 60.8 47.5 44.1 52.2 39.0 37.5 21.8 50.3 35.3 88.7 40.7 61.9 81.9 89.1 83.9 81.1 82.5 73.9 70.9 57.5 71.0 36.8 84.2 46.8 61.3 55.4 74.5 102.9 75.9 43.2 96.0 53.8 53.3 60.7 79.9 72.6 72.7 83.0 99.5 86.5 92.5 99.3 50.7 75.6 65.6 82.9 44.2 52.4 73.8 84.6 54.6 47.3 75.0 64.5 59.3 74.6 112.1 51.9 48.6 65.6 48.2 67.0 94.3 56.9 94.4 93.5 86.9 51.9 53.9 47.2 51.5 61.0 96.8 54.1 46.8 84.0 83.5 28.8 59.6 28.6 29.5 33.3 27.6 30.4 32.4 27.6 26.4 36.3 35.9 127.5 39.4 43.4 22.3 34.3 30.9 16.4 21.7 32.3 21.5 15.8 16.1 17.4 17.1 17.7 14.9 17.1 21.8 33.3 0.0 0.0 0.0 7.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.4 0.0 0.0 0.0 0.0 36.2 28.2 0.0 0.0 0.0 0.0 0.0 0.0 8.9 0.0 0.0 0.0 0.0 38.8 13.5 0.0 0.0 0.0 0.0 0.0 0.0 34.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 13.0 0.0 0.0 0.0 0.0 44.2 5.8 0.0 0.0 0.0 MARK2 "EMK1, PAR-1, PAR-1B, Par1b" ENSG00000072518 "Microtubule affinity regulating kinase 2" Q7KZI7 11 63838928-63911020 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Differentiation, Wnt signaling pathway" "Developmental protein, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA038790, HPA074905" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA038790: AB_10674840, HPA074905: AB_2686722" "unprognostic (1.33e-2)" "unprognostic (2.45e-2)" "unprognostic (1.64e-1)" "prognostic unfavorable (3.21e-4)" "unprognostic (7.13e-2)" "unprognostic (3.82e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (2.73e-3)" "unprognostic (4.41e-1)" "unprognostic (5.79e-2)" "unprognostic (3.94e-3)" "unprognostic (3.77e-1)" "unprognostic (5.20e-3)" "unprognostic (5.15e-3)" "unprognostic (6.78e-2)" "unprognostic (1.03e-1)" "unprognostic (2.40e-1)" 11.3 13.8 12.6 21.1 16.1 24.0 16.8 8.1 16.3 18.5 10.8 25.9 26.1 14.6 7.7 51.8 16.6 14.1 20.9 14.9 9.3 13.9 13.1 17.0 21.5 11.8 9.3 12.0 22.4 19.4 19.8 14.9 11.5 20.5 22.4 8.8 27.0 13.1 20.8 40.9 25.1 16.3 7.3 24.1 20.9 10.6 9.5 23.2 19.5 13.7 24.0 19.3 25.0 17.9 52.0 34.1 26.6 28.6 14.6 18.6 35.2 20.8 20.0 29.5 22.3 34.1 49.5 37.8 35.6 20.8 32.0 57.5 26.9 28.7 24.6 26.7 20.9 40.7 23.9 20.3 17.0 45.9 51.4 10.9 36.8 27.0 21.4 13.5 24.7 33.6 35.7 36.5 19.5 64.4 49.3 29.9 31.7 36.0 24.2 39.9 20.4 39.7 19.1 39.8 37.9 25.4 34.7 90.2 24.3 28.9 65.1 26.4 22.7 30.3 19.1 39.6 23.4 24.5 28.8 36.7 20.1 23.2 25.3 1.4 0.7 2.1 1.3 0.7 2.1 0.9 1.0 1.3 1.0 1.6 0.8 0.9 3.6 1.6 1.1 0.9 0.6 0.7 12.6 16.1 8.1 16.3 14.9 9.3 11.8 9.3 11.5 7.3 9.5 17.9 17.3 6.4 6.8 29.7 18.5 25.2 21.1 9.1 19.4 26.8 30.0 18.2 12.8 27.1 11.9 20.2 8.4 26.0 33.4 90.3 1.9 20.2 0.6 29.5 15.8 14.7 29.9 14.7 43.6 21.4 20.6 11.7 27.0 41.0 17.2 21.1 13.6 13.0 17.9 20.2 30.3 39.9 10.2 26.7 18.5 0.9 12.8 25.0 3.6 29.0 17.0 18.8 36.0 31.7 51.8 27.3 39.4 10.9 15.6 30.4 33.4 8.1 14.5 18.1 19.7 19.6 13.1 9.1 18.4 39.9 34.4 65.0 23.6 16.0 33.6 44.3 MCTS1 MCT-1 ENSG00000232119 "MCTS1 re-initiation and release factor" Q9ULC4 X 120594010-120621159 "Predicted intracellular proteins" "Cell cycle, DNA damage, Growth regulation, Protein biosynthesis, Transcription, Transcription regulation" "Initiation factor" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001045 Supported "Plasma membrane,Cytosol" NA NA 160000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 18: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "HPA001045: " "prognostic unfavorable (1.38e-4)" "unprognostic (1.44e-1)" "unprognostic (4.50e-1)" "unprognostic (9.37e-3)" "unprognostic (7.29e-2)" "prognostic unfavorable (3.27e-5)" "unprognostic (2.94e-3)" "unprognostic (9.59e-2)" "unprognostic (8.28e-2)" "unprognostic (4.89e-2)" "unprognostic (7.42e-2)" "unprognostic (2.82e-1)" "prognostic unfavorable (4.35e-5)" "unprognostic (1.95e-1)" "unprognostic (7.58e-2)" "unprognostic (1.04e-1)" "unprognostic (1.49e-1)" 28.1 31.1 5.5 3.9 5.6 3.9 26.4 5.7 7.0 24.5 4.3 25.9 4.6 19.7 6.3 38.9 19.3 3.0 32.9 6.0 6.0 35.9 40.7 20.8 5.5 5.2 5.0 17.0 39.5 4.9 34.3 3.9 5.2 20.4 5.2 5.5 26.8 3.7 28.5 24.1 23.9 3.1 5.0 28.9 30.5 11.9 5.4 6.7 21.5 6.4 6.7 22.6 24.4 5.7 13.9 8.2 8.2 9.9 16.2 19.2 9.9 13.8 11.9 15.2 17.0 6.6 15.8 18.6 14.3 18.3 23.6 9.6 18.0 17.7 23.4 9.7 8.5 6.3 11.3 6.4 15.6 13.6 10.3 14.1 14.2 14.9 14.2 12.6 19.5 11.0 14.5 10.8 21.9 13.5 11.3 17.5 10.3 27.9 15.7 10.5 7.6 19.2 17.7 6.4 11.0 10.0 8.5 15.2 9.0 10.1 9.1 10.6 16.5 13.3 6.4 14.3 20.7 7.5 12.5 22.2 14.3 18.8 12.9 3.4 5.0 3.5 3.5 5.9 5.6 6.1 4.6 4.4 6.5 4.9 4.2 4.3 2.3 4.9 5.9 8.4 6.1 4.1 5.5 5.6 5.7 7.0 6.0 6.0 5.2 5.0 5.2 5.0 5.4 5.7 53.5 19.2 22.9 13.1 65.4 32.2 65.5 108.4 27.9 14.5 49.3 46.9 80.8 42.9 63.5 46.0 8.4 97.0 52.0 71.3 129.1 87.4 54.4 53.1 55.6 49.9 55.7 22.5 28.2 88.5 182.0 48.5 50.0 43.9 52.0 50.4 51.4 84.4 132.6 15.2 25.5 111.0 71.2 81.7 43.2 88.7 42.0 60.4 62.2 10.3 67.6 27.0 39.1 15.1 25.3 92.7 83.7 27.8 92.0 52.6 118.2 153.5 57.4 21.0 39.5 25.3 66.1 17.7 15.0 50.4 34.5 112.9 46.5 90.0 82.2 75.3 MCTS2P "MCTS2, psiMCT-1" ENSG00000101898 "MCTS family member 2, pseudogene" 20 31547412-31548081 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Not detected" "Not detected" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" HPA001045 Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" Cytosol "Plasma membrane" "HPA001045: " "unprognostic (1.71e-2)" "unprognostic (2.07e-2)" "unprognostic (6.17e-3)" "unprognostic (6.04e-3)" "unprognostic (1.91e-1)" "unprognostic (1.27e-1)" "unprognostic (8.10e-2)" "unprognostic (2.97e-2)" "unprognostic (1.52e-1)" "unprognostic (5.49e-2)" "unprognostic (1.41e-1)" "unprognostic (9.81e-2)" "unprognostic (3.90e-4)" "unprognostic (6.59e-2)" "unprognostic (9.97e-2)" "unprognostic (1.25e-2)" "unprognostic (1.20e-1)" 0.9 0.6 0.2 1.6 0.3 1.5 2.2 0.7 1.3 1.0 0.3 1.6 1.0 1.0 0.5 1.3 1.4 0.6 0.6 0.3 0.4 1.0 0.7 0.8 1.8 0.2 0.5 2.5 0.7 1.7 1.5 0.4 1.2 1.1 1.4 0.8 0.9 0.6 0.6 0.5 1.4 0.1 0.8 1.3 1.3 0.4 2.3 1.6 0.7 2.7 2.1 0.4 8.8 0.0 7.6 7.2 2.2 5.4 0.0 3.2 5.1 10.3 4.3 0.2 4.1 13.3 0.1 4.4 3.8 11.1 0.1 15.0 12.4 0.2 10.1 20.2 2.4 2.3 3.1 17.4 10.7 3.8 7.2 4.1 7.4 3.3 4.2 8.0 9.7 4.6 3.8 3.2 16.0 2.8 0.2 23.1 7.9 8.4 25.4 4.7 3.4 1.0 10.9 10.4 3.4 9.1 3.0 5.6 4.9 7.2 5.5 5.2 11.4 4.0 8.2 3.4 4.7 10.0 6.2 11.9 6.5 0.0 0.3 0.1 0.3 0.2 0.7 0.4 0.4 0.5 0.8 0.5 0.7 0.6 0.0 0.8 0.1 0.4 0.1 0.3 0.2 0.3 0.7 1.3 0.3 0.4 0.2 0.5 0.4 0.1 0.4 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MDGA1 "GPIM, MAMDC3" ENSG00000112139 "MAM domain containing glycosylphosphatidylinositol anchor 1" Q8NFP4 6 37630679-37699306 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 12 "brain: 79.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 34.0;Cone photoreceptor cells: 50.1;Horizontal cells: 57.2" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in all" 9 "cerebellum: 79.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 12.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA031235, HPA050382" Enhanced Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1200000 "Cluster 32: T-cells - Unknown function" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" "Golgi apparatus" "HPA031235: AB_10603017, HPA050382: AB_2681108" "unprognostic (4.67e-2)" "unprognostic (6.97e-3)" "unprognostic (3.24e-1)" "unprognostic (5.69e-4)" "unprognostic (2.75e-2)" "unprognostic (2.41e-1)" "unprognostic (1.45e-2)" "unprognostic (2.00e-1)" "unprognostic (2.02e-2)" "unprognostic (1.45e-1)" "unprognostic (2.16e-2)" "unprognostic (3.00e-1)" "unprognostic (1.52e-5)" "unprognostic (9.19e-3)" "unprognostic (5.28e-3)" "unprognostic (3.80e-3)" "unprognostic (4.60e-2)" 2.6 2.9 4.2 2.6 3.9 0.3 1.6 79.9 5.3 5.4 0.0 2.6 0.5 3.4 1.8 3.7 2.7 3.2 2.3 8.8 4.9 1.2 0.6 3.1 2.6 4.3 4.7 6.5 2.4 4.1 4.8 0.3 7.4 2.1 1.1 4.0 1.1 1.3 1.1 4.9 2.8 2.5 1.0 3.1 2.0 1.5 2.1 0.8 1.4 1.7 2.1 1.9 4.4 3.2 0.2 3.5 4.8 2.4 12.3 4.3 2.2 2.8 2.2 3.5 3.2 0.0 0.0 0.7 0.5 1.7 3.0 5.4 0.5 0.0 1.0 4.9 3.4 0.0 0.3 0.0 0.5 0.0 1.1 1.0 0.0 1.4 0.0 6.8 0.0 0.1 0.0 0.0 1.2 0.0 0.0 0.4 0.0 0.1 0.4 5.9 1.7 0.0 0.8 3.7 4.3 0.0 1.5 0.3 2.6 0.2 3.1 0.6 0.3 3.4 1.4 1.2 4.3 0.0 0.1 0.0 4.2 1.0 2.0 0.0 0.0 0.0 0.3 0.0 0.1 0.2 0.2 0.1 0.0 0.2 0.6 0.1 0.0 0.0 0.0 0.0 0.3 0.1 4.2 3.9 79.9 5.3 8.8 4.9 4.3 4.7 7.4 1.0 2.1 3.2 3.0 9.6 0.5 12.7 2.0 2.3 2.4 0.7 1.2 34.0 0.4 0.6 5.7 1.5 0.8 3.7 50.1 0.2 3.1 0.0 0.0 0.5 2.6 0.6 1.8 1.6 1.8 0.0 4.9 0.0 1.4 4.4 0.5 0.5 0.0 1.1 1.4 0.0 0.1 57.2 4.9 0.0 0.0 0.3 1.1 0.2 10.2 0.3 1.8 1.9 0.0 2.6 4.1 4.0 2.1 0.6 0.0 4.9 1.7 2.0 0.0 0.5 1.9 2.0 0.0 2.6 3.0 2.1 1.3 2.8 3.0 0.7 2.9 0.2 0.0 5.1 MET "DFNB97, HGFR, RCCP2" ENSG00000105976 "MET proto-oncogene, receptor tyrosine kinase" P08581 7 116672196-116798377 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Deafness, Disease variant, FDA approved drug targets, Non-syndromic deafness, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 42.9" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 103.6;Club cells: 99.8;Glandular and luminal cells: 161.4;Pancreatic endocrine cells: 93.9;Prostatic glandular cells: 149.3;Urothelial cells: 128.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in many" 5 "cerebral cortex: 7.5;hippocampal formation: 6.6;midbrain: 2.5;pons: 4.9;white matter: 7.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 203.8;CAPAN-2: 219.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB005282, CAB018577, HPA055607" Approved Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA 179000000 100000000 "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "CAB005282: AB_631940, CAB018577: AB_649068, HPA055607: AB_2682860" "unprognostic (1.60e-2)" "unprognostic (7.71e-2)" "unprognostic (2.53e-2)" "unprognostic (1.58e-1)" "unprognostic (3.57e-3)" "prognostic unfavorable (6.75e-4)" "unprognostic (1.68e-1)" "unprognostic (3.22e-2)" "unprognostic (3.81e-2)" "unprognostic (2.52e-2)" "prognostic unfavorable (1.21e-7)" "unprognostic (1.86e-1)" "unprognostic (1.25e-1)" "unprognostic (5.53e-2)" "unprognostic (8.88e-2)" "unprognostic (2.01e-2)" "unprognostic (2.20e-1)" 10.3 0.8 0.1 3.4 0.6 7.4 8.9 0.1 7.5 13.1 9.6 9.7 6.5 6.4 2.5 6.1 4.7 11.9 6.2 6.6 0.8 20.1 42.9 20.3 2.3 1.1 2.5 0.8 6.6 0.8 3.8 26.4 4.9 6.7 9.3 3.9 8.7 11.2 14.3 7.7 8.2 5.7 0.3 6.0 15.4 0.5 0.5 3.7 17.6 11.0 3.2 18.4 4.4 7.8 203.8 115.3 0.1 0.6 8.6 8.7 7.9 113.7 48.2 60.3 51.1 25.0 219.0 8.4 179.0 72.1 163.3 51.8 19.7 110.0 123.7 0.3 23.4 0.1 112.5 21.4 1.5 0.3 0.2 11.4 42.4 40.6 129.1 109.4 42.4 0.2 4.5 0.8 114.1 5.0 0.1 0.1 17.3 32.9 113.0 0.2 95.3 0.2 105.8 24.0 16.5 0.0 45.4 15.4 44.9 19.8 0.4 0.9 72.3 89.7 30.6 46.7 88.9 2.5 19.1 1.5 99.3 0.3 12.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.6 0.1 7.5 6.6 0.8 1.1 2.5 4.9 0.3 0.5 7.8 32.6 28.9 103.6 0.3 1.0 39.0 70.5 58.1 38.1 6.7 6.5 6.9 12.3 11.5 99.8 31.3 0.0 76.0 0.4 20.5 0.0 38.5 0.0 52.5 11.6 20.1 7.2 0.0 2.6 46.9 7.5 7.4 32.6 161.4 0.0 0.0 3.9 30.5 7.0 0.0 1.0 20.5 18.3 1.3 2.2 0.1 0.6 4.4 3.6 1.9 1.0 7.6 0.0 0.5 7.7 93.9 5.5 0.0 0.4 149.3 11.2 15.6 34.5 0.3 0.0 37.8 5.2 0.0 0.6 7.9 17.8 21.8 1.2 0.0 16.4 128.6 METAP2 "MAP2, MNPEP, p67" ENSG00000111142 "Methionyl aminopeptidase 2" P50579 12 95473520-95515839 "Enzymes, Plasma proteins, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB013025, HPA019095" Enhanced Supported "Plasma membrane,Cytosol" NA NA 70000 "Cluster 6: Non-specific - Transcription" "Cluster 52: Non-specific - Ribosome" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB013025: AB_2533993, HPA019095: AB_1853823" "unprognostic (1.91e-1)" "unprognostic (1.02e-1)" "unprognostic (5.92e-2)" "unprognostic (2.44e-1)" "unprognostic (3.27e-2)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.51e-6)" "unprognostic (1.25e-1)" "unprognostic (2.28e-2)" "unprognostic (1.40e-2)" "unprognostic (8.53e-2)" "unprognostic (1.66e-1)" "unprognostic (1.49e-1)" "unprognostic (2.51e-1)" "unprognostic (1.07e-1)" "unprognostic (2.95e-2)" "unprognostic (1.03e-1)" 52.5 58.0 41.1 51.6 44.5 102.2 55.0 45.0 53.2 46.0 39.7 50.7 36.7 54.2 52.6 54.7 42.6 47.0 65.9 40.2 49.9 55.6 84.5 49.0 78.0 46.5 43.8 60.5 52.7 52.3 36.6 51.3 48.8 43.3 50.9 30.8 40.6 101.0 119.5 58.3 37.7 54.9 42.4 40.3 37.4 61.8 44.7 69.1 51.8 78.7 125.0 62.2 41.5 50.2 192.3 157.8 163.7 129.6 98.4 156.4 125.9 186.0 127.6 177.7 125.7 228.0 88.6 542.1 113.5 133.4 101.9 120.5 187.4 142.4 203.8 131.2 161.2 244.9 113.7 165.6 104.5 313.5 117.1 137.5 148.1 164.9 164.0 210.7 192.9 184.2 321.8 60.5 135.3 125.8 230.3 213.0 204.5 109.4 233.4 179.6 141.5 178.5 123.5 198.3 127.0 165.3 166.0 132.7 169.0 140.6 159.4 146.5 165.1 100.7 98.5 115.0 195.7 87.7 246.8 585.1 58.1 173.7 129.9 77.5 70.5 32.0 60.0 52.2 74.3 114.2 66.8 67.8 66.0 101.8 79.2 74.1 3.4 72.8 65.6 85.3 71.6 46.4 41.1 44.5 45.0 53.2 40.2 49.9 46.5 43.8 48.8 42.4 44.7 50.2 87.0 282.0 238.9 22.9 101.3 233.2 130.2 141.3 97.3 70.6 119.7 95.9 143.6 100.1 133.3 290.6 66.7 146.2 87.7 96.8 164.4 115.2 189.5 114.9 260.0 110.2 91.7 278.4 35.1 145.8 161.5 112.2 53.0 153.7 122.9 140.5 112.1 314.6 98.1 75.7 49.5 119.7 73.2 141.0 89.8 123.3 100.3 83.8 92.5 20.6 103.5 72.6 81.4 26.2 41.4 130.1 105.8 106.8 87.0 108.1 93.4 186.6 92.4 83.8 98.6 137.4 133.4 378.4 207.6 95.2 215.0 172.0 80.7 101.4 144.8 110.5 MFSD1 "FLJ14153, Minerva, UG0581B09" ENSG00000118855 "Major facilitator superfamily domain containing 1" Q9H3U5 3 158732198-158829719 "Predicted intracellular proteins, Predicted membrane proteins" Transport "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hofbauer cells: 214.4;Kupffer cells: 289.7;Macrophages: 212.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Group enriched" "Detected in all" 5 "dendritic cells: 254.5;granulocytes: 246.0;monocytes: 288.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA065858 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane" Cytosol "HPA065858: AB_2685569" "unprognostic (9.94e-2)" "unprognostic (3.12e-3)" "unprognostic (3.54e-2)" "unprognostic (1.00e-1)" "unprognostic (2.16e-2)" "unprognostic (7.37e-2)" "unprognostic (1.28e-2)" "unprognostic (2.61e-2)" "unprognostic (2.52e-1)" "unprognostic (1.15e-1)" "unprognostic (6.48e-2)" "unprognostic (2.92e-1)" "prognostic favorable (5.60e-5)" "unprognostic (1.62e-1)" "unprognostic (6.33e-3)" "unprognostic (4.66e-2)" "unprognostic (2.57e-1)" 39.7 27.4 11.0 38.1 12.9 35.9 26.9 20.2 15.8 22.5 23.8 31.1 25.7 16.1 19.4 35.0 21.4 32.3 17.2 15.7 14.5 30.3 39.5 40.5 34.5 15.8 12.2 17.9 31.5 36.0 7.5 30.7 16.4 26.8 22.2 8.4 48.4 23.4 11.1 23.4 23.2 26.2 11.5 42.0 36.1 18.0 16.1 16.1 27.9 16.9 21.5 40.0 19.6 17.3 83.3 28.9 9.1 26.3 51.0 45.0 35.9 109.7 61.8 46.5 45.9 10.3 82.8 19.7 73.5 81.9 24.1 37.0 22.0 26.7 40.9 68.2 33.7 57.2 24.0 6.7 52.1 206.0 135.7 59.3 38.5 39.7 9.5 15.9 38.0 14.0 39.9 32.9 85.1 19.2 11.3 83.2 8.5 29.9 50.9 19.8 11.3 170.9 18.1 16.3 18.2 29.8 76.7 70.0 25.0 8.3 56.9 100.1 102.8 58.6 23.2 87.3 60.5 98.3 94.4 9.6 74.1 162.0 39.7 102.4 288.8 246.0 36.6 223.4 35.3 54.2 30.3 33.9 254.5 44.5 32.2 35.5 97.1 32.9 187.8 81.8 38.9 252.1 11.0 12.9 20.2 15.8 15.7 14.5 15.8 12.2 16.4 11.5 16.1 17.3 28.5 19.2 34.0 12.1 39.6 21.4 46.2 38.4 33.0 11.8 33.3 19.7 22.2 20.0 51.6 22.0 6.2 27.5 24.1 33.3 19.6 34.0 5.3 13.6 22.7 28.2 22.8 56.0 14.6 28.5 33.6 33.7 23.9 17.2 48.8 8.9 37.1 34.4 214.4 18.5 15.2 28.6 34.6 289.7 90.7 6.7 12.2 212.3 32.0 16.9 88.7 26.0 25.7 15.1 29.4 29.0 29.9 11.3 32.9 30.0 27.1 31.8 59.3 10.5 13.1 11.8 23.8 11.6 8.7 61.2 26.0 56.0 22.3 19.4 28.3 58.4 MIB1 "DIP-1, KIAA1323, MIB, ZZANK2, ZZZ6" ENSG00000101752 "Mindbomb E3 ubiquitin protein ligase 1" Q86YT6 18 21704957-21870953 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Notch signaling pathway, Ubl conjugation pathway" Transferase "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 121.2;Oligodendrocytes: 109.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "REH: 121.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019100, CAB037044" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 68: Epididymis - Unknown function" "Cluster 14: REH - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "CAB037044: AB_1841007, HPA019100: AB_1853934" "unprognostic (1.38e-1)" "unprognostic (6.92e-2)" "unprognostic (7.29e-2)" "unprognostic (6.99e-2)" "unprognostic (5.66e-2)" "unprognostic (3.23e-2)" "unprognostic (8.45e-3)" "unprognostic (2.70e-1)" "unprognostic (5.42e-2)" "unprognostic (4.69e-2)" "unprognostic (3.78e-2)" "unprognostic (4.70e-2)" "unprognostic (8.33e-3)" "unprognostic (4.91e-3)" "unprognostic (1.73e-1)" "unprognostic (4.86e-2)" "unprognostic (1.85e-2)" 8.1 6.3 9.1 6.0 9.1 4.9 11.2 9.2 8.5 11.0 8.0 7.1 5.1 13.0 9.5 8.0 7.1 8.6 6.0 8.4 9.2 11.1 10.4 7.2 7.6 9.5 10.2 11.7 8.1 9.8 5.2 11.0 8.6 10.1 7.0 8.3 8.4 8.5 5.8 9.1 5.2 10.2 10.1 7.2 7.6 8.7 10.3 11.5 13.6 7.0 7.9 8.4 8.2 9.6 19.9 7.6 36.4 25.8 19.5 23.0 9.0 15.6 17.2 10.8 15.6 11.3 7.1 16.9 14.1 21.4 11.8 13.2 21.4 21.0 24.4 22.4 10.4 18.8 9.7 15.9 15.8 38.3 7.8 14.8 23.0 12.6 32.0 16.0 27.8 6.6 26.5 47.5 17.2 9.5 18.9 14.7 9.5 12.2 10.2 121.1 30.3 42.5 18.7 16.9 12.1 30.1 26.8 12.4 13.9 18.6 8.8 25.1 23.9 27.8 14.2 11.7 21.1 25.6 9.5 25.4 11.8 24.1 16.9 0.7 0.3 0.1 0.2 0.1 0.2 0.2 0.3 0.2 0.1 0.1 0.2 0.1 0.3 0.5 0.1 0.2 0.4 0.1 9.1 9.1 9.2 8.5 8.4 9.2 9.5 10.2 8.6 10.1 10.3 9.6 35.7 48.1 22.7 68.2 11.9 21.9 15.1 19.8 24.5 28.8 24.1 19.7 18.1 25.8 31.8 16.5 25.0 13.3 18.2 20.8 3.9 13.4 7.0 29.0 59.2 30.8 24.0 23.1 106.7 12.9 7.5 33.1 10.2 32.4 14.5 16.8 24.3 30.0 12.9 15.2 92.6 17.1 26.4 17.2 16.2 5.6 20.5 14.2 26.6 67.5 19.4 17.7 15.5 121.2 109.6 18.8 7.0 24.8 18.1 48.5 8.7 15.9 30.6 14.5 0.0 35.4 26.9 26.2 12.0 23.4 24.6 25.3 14.5 21.8 10.4 25.3 MISP "C19orf21, Caprice, DKFZp686H18209, MISP1" ENSG00000099812 "Mitotic spindle positioning" Q8IVT2 19 751112-764318 "Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "intestine: 196.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 793.4;Intestinal goblet cells: 230.9;Paneth cells: 646.7;Proximal enterocytes: 1115.2;Undifferentiated cells: 220.7" "Cancer enhanced" "Detected in many" "colorectal cancer: 133.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 121.4;HaCaT: 90.2;hTCEpi: 82.6;MCF7: 63.2;OE19: 76.9;SK-BR-3: 134.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA049511, HPA062232" Enhanced Enhanced "Plasma membrane,Focal adhesion sites" No No "Cluster 9: Intestine - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Focal adhesion sites" "HPA049511: AB_2680798, HPA062232: AB_2684719" "unprognostic (7.48e-2)" "unprognostic (2.04e-1)" "unprognostic (1.44e-1)" "unprognostic (3.99e-2)" "unprognostic (1.02e-1)" "unprognostic (6.50e-2)" "unprognostic (1.78e-3)" "unprognostic (1.64e-2)" "unprognostic (8.64e-2)" "unprognostic (1.49e-1)" "unprognostic (2.56e-3)" "unprognostic (2.09e-1)" "unprognostic (1.19e-3)" "unprognostic (6.78e-3)" "unprognostic (2.29e-1)" "unprognostic (4.80e-1)" "unprognostic (5.27e-2)" 1.3 0.0 0.3 12.1 0.3 0.0 0.9 0.5 0.4 4.4 0.1 95.5 171.0 0.7 0.0 0.3 9.8 11.3 0.0 0.4 0.3 8.8 0.1 9.3 0.1 0.5 0.5 0.3 1.7 0.0 8.1 1.2 0.5 5.6 48.4 0.0 1.0 0.5 0.0 0.6 196.6 3.3 0.2 0.0 22.9 0.5 0.3 0.3 0.1 0.0 0.0 9.0 0.6 0.2 30.4 121.4 0.0 0.1 0.0 0.0 1.4 0.0 0.0 0.1 0.0 42.1 44.2 10.8 11.5 0.0 0.1 90.2 0.0 37.7 0.0 0.0 0.1 0.0 47.0 13.3 0.0 0.0 1.9 0.0 82.6 0.3 4.5 0.0 0.0 0.0 0.0 0.4 0.2 63.2 0.1 0.7 0.1 76.9 24.6 0.2 0.4 1.0 30.1 33.7 1.4 0.4 42.9 134.3 0.1 0.1 29.3 0.0 0.0 0.0 14.8 1.8 0.2 0.6 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.5 0.4 0.4 0.3 0.5 0.5 0.5 0.2 0.3 0.2 0.1 38.5 8.0 0.3 2.9 0.1 4.5 22.5 0.0 0.0 4.7 2.3 0.5 10.0 39.7 11.0 0.0 0.6 0.0 793.4 1.9 39.9 0.6 40.5 1.5 0.8 58.0 0.0 0.2 46.0 6.0 2.4 56.6 14.3 8.9 0.0 0.0 0.0 0.1 0.0 0.3 230.9 28.5 0.0 0.0 0.9 0.0 0.6 0.0 1.0 0.6 0.0 0.0 0.0 0.2 157.7 646.7 0.0 0.1 41.6 1115.2 27.5 41.3 0.0 0.0 0.0 2.6 0.0 1.2 0.0 0.3 2.1 1.6 0.0 220.7 62.1 MLNR GPR38 ENSG00000102539 "Motilin receptor" O43193 13 49220338-49222377 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "bone marrow: 1.3;thyroid gland: 1.7" "Not detected" "Not detected" "Cancer enriched" "Detected in single" 7 "testis cancer: 2.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NTERA-2: 1.3;THP-1: 4.0" "Not detected" "Not detected" HPA070324 Approved "Plasma membrane,Cytosol" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 43: THP-1 - Innate immune response" "Plasma membrane, Cytosol" "HPA070324: " "unprognostic (9.75e-2)" "unprognostic (2.13e-2)" "unprognostic (2.90e-1)" "unprognostic (1.13e-1)" "unprognostic (6.03e-2)" "unprognostic (7.80e-2)" "unprognostic (1.54e-2)" "unprognostic (7.79e-2)" "unprognostic (1.88e-2)" "unprognostic (3.74e-1)" "unprognostic (2.61e-4)" "unprognostic (3.53e-2)" "unprognostic (1.04e-1)" "unprognostic (1.38e-1)" 0.0 0.0 0.1 0.0 0.3 1.3 0.0 0.1 0.1 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.1 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.2 0.0 0.4 0.1 0.4 0.1 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.1 0.1 0.3 0.3 0.4 0.3 0.2 0.4 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 MMP10 STMY2 ENSG00000166670 "Matrix metallopeptidase 10" P09238 11 102770502-102780628 "Cancer-related genes, Enzymes, Predicted secreted proteins" "Collagen degradation" "Hydrolase, Metalloprotease, Protease" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 34 "endometrium 1: 265.4" "Cell type enriched" "Detected in some" 38 "Basal respiratory cells: 3913.2" "Group enriched" "Detected in many" 4 "cervical cancer: 47.8;head and neck cancer: 102.2;lung cancer: 42.3" "Region enhanced" "Detected in single" "thalamus: 1.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 11.8;HUVEC TERT2: 15.1;SCLC-21H: 4.7" CAB002159 Uncertain Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" NA NA 765000 "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB002159: AB_564103" "unprognostic (8.76e-2)" "unprognostic (3.38e-1)" "unprognostic (1.98e-3)" "unprognostic (2.72e-3)" "unprognostic (7.17e-3)" "unprognostic (1.52e-2)" "unprognostic (5.67e-8)" "unprognostic (2.08e-3)" "unprognostic (2.20e-1)" "unprognostic (1.75e-1)" "unprognostic (1.67e-2)" "unprognostic (2.67e-1)" "unprognostic (6.99e-5)" "unprognostic (2.66e-2)" "unprognostic (7.98e-2)" "unprognostic (5.46e-2)" "prognostic favorable (7.12e-4)" 0.1 0.0 0.1 7.7 0.0 0.1 0.1 0.0 0.8 1.2 0.0 0.4 1.1 265.4 0.0 0.2 0.0 1.3 0.0 0.2 0.3 0.1 1.0 2.0 0.1 0.1 0.3 0.2 0.2 0.0 0.0 1.3 0.3 1.4 0.2 0.0 1.6 0.0 0.0 0.1 0.8 0.2 0.0 0.0 2.9 0.5 1.9 0.6 0.0 0.2 0.7 4.4 3.2 0.0 0.0 0.1 0.8 0.2 0.0 0.0 0.2 11.8 0.6 0.1 0.1 0.3 0.0 0.0 3.3 1.8 0.2 2.7 0.0 1.3 0.0 0.0 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.4 0.5 0.0 15.1 0.0 0.7 0.0 0.0 0.0 0.0 0.3 2.8 0.5 1.6 0.0 0.0 0.0 0.0 0.6 4.7 0.0 2.4 0.0 0.0 0.8 0.0 0.0 1.9 3.5 1.2 0.4 0.5 0.0 0.0 0.1 0.6 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.2 0.3 0.1 0.3 0.3 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.8 51.3 3913.2 0.0 0.0 0.7 0.0 0.1 0.0 85.4 29.5 0.0 0.0 0.0 0.4 0.0 34.0 6.1 6.4 2.5 9.0 0.0 0.0 0.0 14.6 0.0 6.3 0.0 12.4 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 22.4 0.0 9.5 1.3 0.0 0.6 0.0 0.0 1.6 0.0 0.0 0.0 0.0 102.5 0.1 0.0 0.0 42.5 0.0 0.1 29.3 0.0 0.0 0.0 11.7 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.1 8.2 MMP24 MT5-MMP ENSG00000125966 "Matrix metallopeptidase 24" Q9Y5R2 20 35226690-35276998 "Enzymes, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 40.0" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 16.0;Excitatory neurons: 24.6;Horizontal cells: 15.2;Inhibitory neurons: 38.4;Oligodendrocyte precursor cells: 12.5;Oligodendrocytes: 12.0;Proximal tubular cells: 11.4" "Cancer enhanced" "Detected in many" "renal cancer: 11.4;testis cancer: 10.8" "Region enriched" "Detected in all" 5 "cerebellum: 40.0" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A549: 36.3;CACO-2: 56.0;EFO-21: 15.8;RPTEC TERT1: 24.6;U-2 OS: 17.7" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 51.5" "HPA049280, HPA078816" Approved Approved "Nucleoli,Plasma membrane" "Secreted to extracellular matrix" Yes No "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 39: CACO-2 - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoli, Plasma membrane" "HPA049280: , HPA078816: " "unprognostic (1.52e-3)" "unprognostic (1.36e-1)" "unprognostic (1.18e-1)" "unprognostic (4.51e-4)" "unprognostic (2.47e-2)" "unprognostic (7.61e-3)" "unprognostic (1.22e-1)" "unprognostic (4.59e-2)" "unprognostic (2.32e-2)" "unprognostic (8.82e-2)" "unprognostic (9.20e-3)" "unprognostic (7.12e-2)" "prognostic favorable (8.17e-11)" "unprognostic (3.32e-2)" "unprognostic (5.63e-2)" "unprognostic (1.69e-2)" "unprognostic (9.90e-4)" 3.4 1.0 6.1 0.5 5.8 0.7 0.5 40.0 8.1 0.7 3.5 0.7 2.1 1.3 0.1 0.3 2.2 0.6 0.6 6.0 5.6 7.8 0.5 4.7 0.4 4.4 5.6 0.4 5.8 0.3 3.8 0.2 5.4 1.7 0.2 2.5 0.5 4.2 0.3 1.2 1.4 2.0 2.7 0.4 0.6 0.4 7.2 0.0 0.7 0.1 0.0 0.4 0.3 4.8 0.6 36.3 0.1 0.2 0.2 0.0 1.0 1.9 2.3 3.8 2.0 56.0 9.7 0.0 15.8 2.5 1.2 0.6 8.5 0.0 1.6 0.2 0.3 1.9 1.2 0.6 0.0 0.1 0.4 0.2 0.2 0.1 0.1 1.0 0.1 0.1 0.1 0.5 0.4 0.5 0.1 0.2 13.6 0.1 2.4 0.1 0.2 0.0 24.6 0.1 14.1 9.7 2.5 0.7 0.3 2.9 0.5 0.3 0.6 7.4 17.7 1.8 0.7 0.3 0.2 0.1 1.6 0.2 1.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 6.1 5.8 40.0 8.1 6.0 5.6 4.4 5.6 5.4 2.7 7.2 4.8 0.3 16.0 1.5 5.2 0.0 0.1 0.2 0.0 0.0 3.9 0.2 0.8 0.5 8.6 1.3 1.8 0.0 0.1 0.1 0.7 5.9 8.5 0.6 0.8 0.3 1.4 0.0 0.0 24.6 0.9 0.1 0.6 0.0 0.5 0.0 0.1 0.4 0.4 0.0 15.2 38.4 0.1 0.0 0.6 0.0 0.0 0.3 0.1 1.8 10.3 0.0 0.2 0.0 12.5 12.0 1.9 0.1 0.0 0.0 0.4 2.3 11.4 0.0 0.4 0.0 0.2 0.2 0.1 0.3 0.0 0.3 0.0 0.2 0.0 0.1 0.1 MPI ENSG00000178802 "Mannose phosphate isomerase" P34949 15 74890005-74902219 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Isomerase "Congenital disorder of glycosylation, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Proximal enterocytes: 70.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007200 Approved Approved "Plasma membrane,Cytosol" NA NA 350000 "Cluster 20: T-cells - T-cell receptor" "Cluster 39: Non-specific - Mitochondria" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" Cytosol "Plasma membrane" "HPA007200: AB_1854079" "unprognostic (1.38e-1)" "unprognostic (7.18e-2)" "unprognostic (1.63e-1)" "unprognostic (1.65e-3)" "unprognostic (7.34e-2)" "prognostic unfavorable (2.39e-4)" "unprognostic (1.79e-1)" "unprognostic (2.76e-1)" "unprognostic (3.20e-1)" "unprognostic (2.93e-2)" "unprognostic (1.47e-1)" "unprognostic (1.27e-1)" "unprognostic (3.34e-2)" "unprognostic (2.11e-1)" "unprognostic (1.15e-1)" "unprognostic (2.09e-1)" "unprognostic (6.58e-2)" 18.9 50.5 45.4 16.7 47.3 11.7 20.1 52.2 49.2 23.9 41.1 31.8 45.6 23.6 35.3 27.7 27.8 16.0 44.8 46.6 47.9 31.2 39.1 14.9 20.9 55.5 50.1 30.6 31.8 31.1 22.9 16.2 56.2 27.5 31.4 33.6 23.7 22.9 52.2 16.5 33.0 22.5 45.7 23.0 20.9 26.2 50.0 23.2 23.2 70.9 24.2 24.2 19.5 47.1 27.2 36.9 29.8 34.0 66.7 32.2 26.0 22.8 37.2 38.4 53.4 36.7 35.0 38.3 48.6 33.6 30.6 65.9 60.0 66.7 36.2 29.4 74.9 68.8 35.3 39.9 47.5 32.0 19.4 43.1 16.9 36.2 64.4 58.1 52.9 45.2 23.4 30.7 50.1 23.2 34.6 14.2 16.4 40.9 31.0 35.0 28.0 94.9 45.5 30.4 55.7 24.4 26.7 47.5 28.7 43.5 65.3 21.9 24.1 22.9 19.4 17.3 22.6 75.0 48.4 25.1 47.9 45.8 17.1 2.3 16.2 5.7 28.2 17.0 37.0 27.4 38.3 32.6 23.0 31.9 56.0 40.8 2.7 43.1 15.5 19.1 53.1 29.0 45.4 47.3 52.2 49.2 46.6 47.9 55.5 50.1 56.2 45.7 50.0 47.1 5.6 6.4 15.0 7.8 10.8 1.9 7.6 16.4 5.2 23.4 9.2 10.7 54.1 7.2 10.9 14.7 4.2 31.8 9.1 28.3 15.6 19.6 18.9 5.6 9.2 9.6 10.8 4.2 4.9 8.8 11.4 10.9 6.1 8.5 15.2 13.3 6.1 18.8 23.9 35.3 6.1 19.0 8.2 7.2 2.2 31.3 11.1 6.6 3.6 3.7 9.7 20.7 12.3 2.0 6.9 12.2 33.2 8.6 11.8 7.2 70.1 31.4 7.8 16.7 6.6 8.2 10.1 34.5 9.0 9.1 2.7 16.3 11.1 21.0 16.4 6.2 MPL "CD110, THPOR, TPOR" ENSG00000117400 "MPL proto-oncogene, thrombopoietin receptor" P40238 1 43337818-43354466 "Cancer-related genes, CD markers, Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Group enriched" "Detected in some" 5 "Erythroid cells: 3.0;Excitatory neurons: 2.0;Oligodendrocytes: 1.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "neutrophil: 1.4" "Lineage enriched" "Detected in single" 4 "granulocytes: 1.4" "Cell line enriched" "Detected in some" 57 "HEL: 77.4" "Region enhanced" "Detected in single" "cerebral cortex: 1.5" "Low region specificity" "Detected in many" HPA007619 Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 36: HEL - Hemostasis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Nuclear membrane" "HPA007619: AB_1854080" "unprognostic (2.74e-1)" "unprognostic (6.56e-2)" "unprognostic (2.95e-1)" "unprognostic (8.71e-2)" "unprognostic (1.37e-2)" "unprognostic (1.06e-3)" "unprognostic (1.19e-1)" "unprognostic (1.22e-2)" "unprognostic (5.83e-2)" "unprognostic (1.03e-1)" "unprognostic (5.94e-4)" "unprognostic (1.51e-1)" "unprognostic (1.19e-4)" "unprognostic (2.39e-1)" "unprognostic (3.26e-1)" "unprognostic (1.03e-4)" "unprognostic (1.42e-1)" 0.6 0.4 0.8 0.2 1.7 1.8 0.4 0.8 1.3 0.3 0.1 0.3 0.3 0.7 1.2 0.5 0.8 0.3 1.0 0.6 1.2 0.4 0.4 0.6 0.2 1.2 1.0 2.9 0.8 0.4 0.0 0.3 1.1 0.9 0.4 1.5 0.4 0.7 0.6 0.5 0.2 0.7 0.7 0.4 0.5 1.2 1.1 0.1 0.9 0.3 0.1 0.2 0.0 2.8 0.4 0.7 0.1 0.2 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.7 1.3 0.1 0.3 0.1 0.0 0.6 0.0 0.2 0.0 0.4 0.1 77.4 1.2 0.4 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.3 0.0 0.1 0.0 0.1 0.0 0.3 0.0 0.2 0.5 0.1 0.1 0.2 0.0 0.2 0.7 0.6 0.4 0.2 0.6 0.1 0.2 0.2 0.3 0.0 0.1 0.1 0.2 0.1 0.1 0.2 0.2 0.0 0.0 0.0 0.0 0.9 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.0 0.2 0.2 0.2 1.4 0.1 0.1 0.3 0.1 1.8 0.8 1.7 0.8 1.3 0.6 1.2 1.2 1.0 1.1 0.7 1.1 2.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 MPP1 "DXS552E, PEMP" ENSG00000130830 "Membrane palmitoylated protein 1" Q00013 X 154778684-154821007 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 116.8" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 410.9;Erythroid cells: 393.8;Hofbauer cells: 291.9;Macrophages: 155.9;Syncytiotrophoblasts: 454.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 215.7;neutrophil: 202.1" "Group enriched" "Detected in all" 8 "dendritic cells: 57.7;granulocytes: 215.7;monocytes: 98.8" "Cell line enhanced" "Detected in many" "HEL: 218.0;REH: 136.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA076675 Enhanced Supported "Plasma membrane,Centriolar satellite" NA NA 650000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 3: HMC-1 - Innate immune response" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane" "Centriolar satellite" "HPA076675: " "unprognostic (2.15e-1)" "unprognostic (4.06e-2)" "unprognostic (4.52e-2)" "unprognostic (1.83e-3)" "unprognostic (7.14e-2)" "unprognostic (2.60e-2)" "unprognostic (7.47e-2)" "unprognostic (1.54e-1)" "unprognostic (1.82e-1)" "unprognostic (7.79e-2)" "unprognostic (3.77e-3)" "unprognostic (1.70e-3)" "prognostic favorable (4.60e-6)" "unprognostic (6.69e-2)" "unprognostic (2.53e-2)" "unprognostic (4.68e-2)" "unprognostic (6.67e-3)" 24.1 27.2 21.0 27.1 22.0 116.8 16.5 26.2 29.7 11.6 18.6 17.2 59.4 13.4 5.3 10.5 15.7 24.3 26.0 22.5 25.2 42.9 37.5 28.3 24.9 28.3 21.9 10.6 34.6 30.7 9.7 86.5 30.7 15.5 17.6 10.6 23.7 18.1 29.2 10.2 47.3 19.7 22.5 40.9 11.8 7.1 27.3 72.8 14.0 27.2 12.5 21.3 10.0 28.2 41.4 8.3 18.7 18.7 19.0 20.1 59.5 15.3 23.3 25.3 30.8 23.7 3.7 32.8 29.3 17.1 67.9 4.6 21.6 6.9 19.9 34.9 38.0 218.0 5.7 25.3 28.6 44.4 121.4 19.4 9.0 28.2 7.0 25.9 58.5 42.1 96.1 5.3 28.7 0.2 102.6 60.3 1.9 3.8 28.2 136.0 4.8 15.5 14.8 3.3 4.7 7.5 12.7 1.2 13.3 18.5 3.2 25.8 26.6 23.2 12.5 51.8 41.7 36.6 52.9 12.5 32.7 61.7 11.1 49.7 95.6 215.7 5.1 76.6 6.0 7.8 5.9 5.7 57.7 2.7 15.4 7.9 202.1 10.1 98.8 15.5 3.5 79.1 21.0 22.0 26.2 29.7 22.5 25.2 28.3 21.9 30.7 22.5 27.3 28.2 18.3 3.2 11.2 8.1 6.3 8.7 4.8 0.2 8.0 10.2 7.1 5.1 17.0 41.5 6.2 7.3 4.2 410.9 6.9 16.3 21.5 11.7 0.6 3.5 5.7 18.9 11.5 393.8 16.1 2.8 27.0 11.4 1.1 6.4 90.6 9.6 11.7 10.6 291.9 16.8 17.1 4.4 0.0 104.7 30.2 2.4 8.7 155.9 10.6 15.9 52.5 15.4 9.2 6.0 5.9 3.7 4.1 13.2 8.1 3.1 57.4 66.3 2.2 8.2 0.0 8.6 10.3 0.7 6.8 6.4 6.0 454.4 9.9 14.5 5.8 1.2 MPZL1 "FLJ21047, PZR" ENSG00000197965 "Myelin protein zero like 1" O95297 1 167721192-167791919 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 4 "neutrophil: 183.8" "Lineage enriched" "Detected in all" 4 "granulocytes: 183.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026966, HPA063538" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 39: CACO-2 - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA026966: AB_10600931, HPA063538: AB_2685034" "unprognostic (6.54e-2)" "unprognostic (9.26e-3)" "unprognostic (4.59e-2)" "unprognostic (4.88e-1)" "unprognostic (2.18e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (4.27e-6)" "prognostic unfavorable (3.98e-4)" "unprognostic (1.22e-1)" "unprognostic (3.41e-2)" "unprognostic (2.59e-1)" "unprognostic (2.27e-1)" "prognostic unfavorable (3.99e-7)" "unprognostic (3.55e-1)" "unprognostic (2.35e-1)" "prognostic unfavorable (8.08e-4)" "unprognostic (4.21e-2)" 74.8 34.1 23.1 49.2 21.6 8.3 91.6 22.0 21.8 63.1 40.1 60.1 40.8 50.0 27.4 52.9 60.1 67.7 52.4 22.1 28.3 28.6 23.0 42.3 35.2 25.7 30.0 46.4 27.5 28.4 33.0 68.9 30.7 41.8 59.4 12.7 73.1 38.9 14.7 34.0 41.0 62.6 26.4 29.2 43.8 48.2 28.6 29.3 39.5 26.8 45.9 74.7 51.3 24.9 88.5 126.3 96.9 75.8 303.4 137.2 304.8 134.5 172.7 86.3 106.4 234.4 119.5 31.0 152.9 171.6 76.1 144.2 97.5 149.0 72.6 70.9 52.8 25.5 63.5 56.7 188.5 30.2 16.1 126.1 183.5 137.8 153.4 121.4 116.4 93.6 97.1 63.5 103.0 29.3 103.6 36.2 61.9 176.7 53.5 62.5 82.7 137.5 131.4 84.6 55.7 91.8 119.6 122.4 69.7 221.9 66.6 16.0 132.8 97.9 44.1 127.5 73.8 94.0 157.2 142.8 140.8 35.3 15.8 7.7 29.1 20.0 2.8 24.8 1.3 14.7 2.8 4.1 38.5 8.8 7.7 2.6 183.8 10.4 34.6 43.9 0.5 11.0 23.1 21.6 22.0 21.8 22.1 28.3 25.7 30.0 30.7 26.4 28.6 24.9 52.9 28.9 30.0 31.0 15.1 76.3 78.5 57.6 35.9 8.8 75.9 73.9 6.3 20.0 49.6 20.2 6.2 128.7 21.1 67.1 5.9 63.2 1.8 14.5 40.4 56.7 47.8 10.1 32.8 75.6 145.2 118.2 41.3 23.0 3.8 75.3 24.3 23.3 37.7 10.1 27.9 39.7 20.3 28.2 31.9 4.9 69.9 23.5 16.0 60.0 84.0 11.8 3.1 141.8 1.7 81.0 41.6 83.8 23.5 141.7 55.5 10.1 28.3 13.9 19.7 18.6 48.6 8.9 26.8 41.2 55.5 76.9 8.6 49.4 61.0 57.7 MRGPRF "GPR140, GPR168, MGC21621, mrgF" ENSG00000172935 "MAS related GPR family member F" Q96AM1 11 69004395-69013382 "G-protein coupled receptors, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "endometrium 1: 171.2;intestine: 159.2" "Cell type enhanced" "Detected in many" "Fibroblasts: 33.3;Leydig cells: 66.2;Peritubular cells: 100.8;Sertoli cells: 52.6;Smooth muscle cells: 63.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 67.6;ASC TERT1: 30.0;BJ: 39.5;BJ hTERT+: 99.1;BJ hTERT+ SV40 Large T+: 36.8;fHDF/TERT166: 30.8;U-2197: 46.8" "Region enriched" "Detected in many" 5 "cerebellum: 14.8" "Region enhanced" "Detected in some" "spinal cord: 4.8" HPA028811 Approved Supported "Nuclear membrane,Plasma membrane" NA NA "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nuclear membrane, Plasma membrane" "HPA028811: AB_10603875" "unprognostic (2.49e-2)" "unprognostic (3.89e-2)" "unprognostic (1.20e-1)" "unprognostic (9.03e-2)" "unprognostic (5.16e-2)" "unprognostic (6.52e-3)" "unprognostic (3.20e-1)" "unprognostic (1.33e-1)" "unprognostic (1.00e-1)" "unprognostic (1.36e-1)" "unprognostic (8.32e-2)" "unprognostic (1.47e-1)" "unprognostic (4.55e-7)" "unprognostic (2.75e-2)" "unprognostic (2.27e-1)" "unprognostic (2.86e-2)" "unprognostic (3.62e-3)" 41.7 3.8 2.6 12.8 2.9 0.0 32.5 12.0 3.9 103.6 5.5 159.2 9.3 171.2 14.2 16.2 98.0 16.7 13.7 2.4 3.1 17.1 7.0 18.7 4.5 4.7 2.8 37.0 3.4 0.5 4.1 11.6 3.3 48.3 8.9 0.2 10.8 45.6 5.1 15.2 38.3 59.3 2.8 13.4 44.1 7.3 2.8 0.7 10.7 3.0 1.3 75.2 65.6 2.5 0.0 0.1 0.1 0.0 67.6 30.0 1.4 39.5 99.1 36.8 24.3 0.0 1.8 0.0 0.8 30.8 0.1 0.1 0.1 0.0 6.8 0.0 0.0 0.0 2.8 0.0 8.5 0.0 0.0 22.1 0.0 23.5 0.0 0.1 0.0 0.2 0.0 0.0 0.6 0.0 0.0 2.9 1.5 0.8 0.1 0.0 3.4 0.1 0.0 0.0 0.1 0.2 0.0 0.1 0.0 2.5 0.0 0.0 0.0 22.4 0.0 46.8 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 2.9 12.0 3.9 2.4 3.1 4.7 2.8 3.3 2.8 2.8 2.5 3.2 0.0 0.0 0.0 0.6 5.0 0.2 0.0 1.2 0.0 0.3 2.3 0.6 2.8 0.0 11.0 0.0 0.7 0.1 0.0 0.0 0.0 4.9 1.1 20.6 2.3 0.0 0.0 1.1 0.0 0.6 33.3 0.5 0.8 0.0 0.0 3.9 3.8 1.1 0.0 0.2 0.0 0.0 0.0 7.3 7.9 66.2 0.2 7.2 3.7 0.0 3.0 0.0 0.0 0.2 0.1 0.0 100.8 0.1 0.3 0.0 0.9 0.0 0.3 52.6 19.1 63.7 1.3 0.5 0.4 3.8 1.1 0.6 0.6 0.0 0.4 MRNIP "C5orf45, DKFZp686L2452, LOC51149, MGC65027, MGC78537" ENSG00000161010 "MRN complex interacting protein" Q6NTE8 5 179835133-179862173 "Predicted intracellular proteins" "DNA damage, DNA repair" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal tubular cells: 46.9;Endometrial ciliated cells: 49.7;Glandular and luminal cells: 31.3;Respiratory ciliated cells: 29.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA043975 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 24: B-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA043975: AB_2678754" "unprognostic (4.97e-2)" "unprognostic (2.79e-1)" "unprognostic (7.98e-2)" "unprognostic (1.08e-1)" "unprognostic (1.63e-1)" "unprognostic (5.15e-3)" "unprognostic (1.68e-3)" "unprognostic (2.51e-2)" "unprognostic (1.10e-1)" "unprognostic (6.11e-2)" "unprognostic (3.63e-3)" "unprognostic (2.05e-2)" "prognostic unfavorable (2.64e-5)" "unprognostic (1.18e-1)" "unprognostic (3.73e-1)" "unprognostic (7.00e-2)" "unprognostic (1.43e-3)" 7.8 7.2 10.5 3.5 10.6 1.4 9.5 13.1 12.9 21.8 11.5 12.3 2.5 11.4 5.9 6.4 16.7 2.2 7.1 10.6 10.3 13.1 10.0 8.9 5.5 10.8 10.6 21.0 10.3 5.2 19.2 1.5 10.8 15.4 2.8 3.0 9.9 7.1 5.4 7.9 17.1 3.8 10.0 19.0 8.8 10.1 10.6 2.7 15.5 2.7 5.3 12.7 13.7 11.8 1.0 1.9 3.5 8.4 7.4 6.6 4.0 2.5 2.3 3.2 4.8 2.5 3.2 4.1 2.9 1.3 1.4 2.6 4.4 8.3 2.6 3.7 3.5 1.3 4.3 2.1 4.6 1.7 1.6 4.9 7.0 3.7 3.0 2.4 3.6 4.1 2.0 1.8 3.5 3.9 2.8 1.7 1.7 1.3 1.9 3.3 1.4 3.2 5.7 0.8 6.6 2.1 1.2 3.3 3.1 2.6 4.1 1.4 0.7 1.8 1.4 1.4 1.5 2.2 1.4 2.9 1.7 2.7 1.3 1.5 0.6 2.9 2.7 0.7 3.8 8.0 4.0 3.2 0.8 10.2 6.4 4.5 0.9 3.5 0.9 4.9 2.6 1.9 10.5 10.6 13.1 12.9 10.6 10.3 10.8 10.6 10.8 10.0 10.6 11.8 22.4 16.0 15.6 0.0 6.2 0.0 0.0 0.0 0.0 0.0 13.7 21.1 0.0 0.0 11.8 18.4 0.0 10.5 11.6 0.0 46.9 5.1 0.0 49.7 19.0 5.8 0.0 0.0 0.0 2.2 6.8 9.7 0.0 31.3 11.4 20.1 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.3 0.0 0.0 3.1 0.0 0.0 0.0 0.0 3.3 0.0 0.0 3.0 0.0 0.0 14.5 29.9 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 9.3 7.6 18.4 0.0 0.0 MRPL42 "HSPC204, MRP-L31, MRPL31, MRPS32, PTD007, RPML31" ENSG00000198015 "Mitochondrial ribosomal protein L42" Q9Y6G3 12 93467514-93516214 "Predicted intracellular proteins, Ribosomal proteins" "Ribonucleoprotein, Ribosomal protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 397.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039398 Approved Supported "Plasma membrane,Mitochondria" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 1: Thyroid gland - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Mitochondria" "HPA039398: AB_10673529" "unprognostic (9.32e-2)" "unprognostic (4.18e-2)" "unprognostic (4.50e-2)" "unprognostic (3.89e-2)" "unprognostic (1.27e-2)" "unprognostic (1.75e-1)" "prognostic unfavorable (7.49e-4)" "unprognostic (6.13e-2)" "unprognostic (3.66e-2)" "unprognostic (1.95e-1)" "unprognostic (2.18e-2)" "unprognostic (1.90e-1)" "unprognostic (1.51e-1)" "unprognostic (2.45e-2)" "unprognostic (4.92e-1)" "unprognostic (1.62e-1)" "prognostic favorable (8.12e-4)" 15.7 26.7 6.8 8.8 8.3 13.9 14.9 11.6 9.0 15.7 9.9 16.9 13.5 14.5 10.9 19.3 14.2 8.1 17.2 7.9 9.8 21.4 20.4 12.8 12.2 7.5 8.3 14.3 13.8 23.4 15.4 11.3 8.6 15.9 16.8 6.1 14.0 10.5 12.0 14.9 13.5 13.8 6.3 10.8 15.9 14.4 7.7 19.2 14.0 14.4 14.9 16.6 16.6 11.7 30.5 42.3 53.5 33.8 25.5 36.8 36.5 43.0 33.0 45.4 32.9 51.8 11.6 49.9 16.3 32.1 29.8 22.4 61.5 48.0 74.3 50.6 40.5 45.0 26.8 61.9 41.9 74.0 21.3 31.0 44.4 48.4 60.5 42.2 46.5 53.0 61.3 19.0 54.0 36.1 67.2 49.3 65.1 52.8 55.9 48.1 25.5 40.4 49.2 77.0 39.8 32.0 36.0 39.3 41.3 42.0 35.5 33.4 29.1 26.5 22.1 21.3 49.6 31.2 49.0 46.1 12.2 45.7 41.5 21.0 14.4 20.4 14.7 21.2 18.9 25.9 19.4 16.6 16.4 23.7 21.3 21.8 8.3 27.0 20.4 11.2 28.1 16.3 6.8 8.3 11.6 9.0 7.9 9.8 7.5 8.3 8.6 6.3 7.7 11.7 55.0 28.9 35.5 13.4 59.9 67.3 97.6 131.6 50.1 34.9 48.7 38.1 82.6 42.9 82.5 46.0 60.5 96.7 41.4 38.2 213.2 86.2 397.6 87.5 61.3 48.7 93.2 66.7 16.2 77.4 133.1 54.5 48.9 48.6 58.4 50.7 32.9 48.4 54.0 47.1 22.1 66.8 107.8 34.1 47.9 165.0 51.6 32.6 60.5 6.5 35.2 22.1 54.6 20.1 20.3 89.8 49.9 56.1 59.8 109.8 44.9 146.5 96.7 41.6 52.6 42.3 59.8 230.5 66.6 59.7 75.0 95.5 51.7 100.1 82.1 115.4 MS4A14 "DKFZp434H092, FLJ32856, MS4A16, NYD-SP21" ENSG00000166928 "Membrane spanning 4-domains A14" Q96JA4 11 60378530-60417756 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 6 "testis: 73.0" "Group enriched" "Detected in some" 44 "Early spermatids: 262.3;Late spermatids: 672.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 5.5;non-classical monocyte: 8.0" "Lineage enriched" "Detected in many" 5 "monocytes: 8.0" "Cell line enriched" "Detected in single" 23 "THP-1: 9.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA058973 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 78: Testis - Spermatogenesis" "Cluster 43: THP-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA058973: " "unprognostic (1.78e-1)" "unprognostic (1.76e-1)" "unprognostic (5.75e-2)" "unprognostic (1.77e-1)" "unprognostic (1.27e-1)" "unprognostic (1.79e-2)" "unprognostic (1.24e-1)" "unprognostic (3.45e-2)" "unprognostic (4.00e-2)" "unprognostic (1.05e-1)" "unprognostic (1.77e-1)" "unprognostic (2.14e-1)" "unprognostic (4.50e-6)" "unprognostic (3.73e-2)" "unprognostic (7.16e-3)" "unprognostic (8.40e-2)" "unprognostic (7.11e-2)" 5.1 3.7 6.2 3.5 5.6 0.6 3.6 5.8 8.8 1.2 7.5 2.7 0.7 0.9 0.6 0.9 1.3 0.9 2.6 5.8 6.3 1.8 2.0 11.9 1.3 7.7 6.8 0.7 1.3 0.3 1.5 2.4 7.2 1.8 1.1 0.4 1.9 0.5 0.9 0.9 2.7 1.2 6.0 10.4 1.2 73.0 8.5 0.3 1.5 0.3 1.9 2.0 1.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 9.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.0 3.4 0.0 0.0 5.5 0.0 0.0 0.0 0.0 1.4 0.3 0.0 0.0 0.0 0.0 8.0 0.0 0.0 0.9 6.2 5.6 5.8 8.8 5.8 6.3 7.7 6.8 7.2 6.0 8.5 8.0 0.2 0.0 1.1 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 262.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 7.3 5.5 672.0 4.1 10.4 0.0 3.7 5.7 0.0 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 0.0 0.0 0.7 0.0 6.6 0.1 0.0 6.5 3.4 0.0 0.3 0.1 0.1 0.0 0.0 0.0 MS4A15 ENSG00000166961 "Membrane spanning 4-domains A15" Q8N5U1 11 60756867-60776733 "Predicted membrane proteins" Receptor "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enriched" "Detected in some" 12 "lung: 43.9" "Cell type enriched" "Detected in some" 15 "Alveolar cells type 1: 96.1" "Cancer enhanced" "Detected in many" "lung cancer: 6.3" "Not detected" "Not detected" "Immune cell enhanced" "Detected in single" "T-reg: 3.2" "Lineage enriched" "Detected in single" 12 "T-cells: 3.2" "Cell line enhanced" "Detected in some" "EFO-21: 1.2;HEL: 3.6;JURKAT: 1.6;MOLT-4: 1.6;U-266/70: 4.0;U-266/84: 2.1" "Region enriched" "Detected in some" 28 "olfactory bulb: 166.8" "Region enriched" "Detected in single" 26 "olfactory bulb: 20.2" HPA054563 Approved "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 19: Lung - Lung function" "Cluster 29: U-266 - Adaptive immune response" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" Cytosol "HPA054563: " "unprognostic (1.85e-1)" "unprognostic (4.31e-3)" "unprognostic (8.59e-2)" "unprognostic (5.89e-4)" "unprognostic (4.49e-1)" "unprognostic (1.09e-3)" "unprognostic (3.92e-3)" "unprognostic (5.43e-3)" "unprognostic (1.20e-1)" "unprognostic (7.30e-2)" "unprognostic (3.14e-1)" "unprognostic (1.04e-9)" "unprognostic (7.02e-2)" "unprognostic (8.63e-2)" "unprognostic (2.75e-1)" "unprognostic (1.47e-1)" 0.3 0.2 0.2 0.4 0.2 0.1 2.2 0.3 0.4 0.3 0.2 0.3 1.0 1.2 0.3 0.4 1.0 0.2 0.3 0.7 0.2 0.1 0.0 43.9 0.5 0.4 0.2 1.8 0.1 0.0 0.0 0.7 0.4 0.3 0.6 0.4 0.1 1.2 0.0 0.0 2.2 1.6 0.1 0.3 0.4 0.6 0.2 3.8 0.3 0.0 1.8 0.8 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 3.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 1.6 0.5 1.0 0.0 0.0 1.6 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.3 0.0 0.0 4.0 2.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.8 0.1 0.0 0.0 0.5 0.2 0.0 0.2 0.0 0.0 3.2 0.2 0.2 0.2 0.3 0.4 0.7 0.2 0.4 0.2 0.4 0.1 0.2 0.3 0.2 96.1 5.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 6.2 0.0 0.0 0.9 0.0 0.0 0.0 0.0 5.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.6 0.1 0.0 0.0 1.3 0.1 0.0 0.0 0.3 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.4 0.0 0.0 2.5 0.0 1.5 0.0 0.0 0.0 0.0 0.0 3.0 0.0 0.0 2.1 0.2 0.1 0.0 0.0 MTCP1 "P13MTCP1, p8MTCP1, TCL1C" ENSG00000214827 "Mature T cell proliferation 1" P56278 X 155064034-155147937 "Cancer-related genes, Disease related genes, Predicted intracellular proteins" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Erythroid cells: 3.2;Respiratory ciliated cells: 2.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 13.6" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA032040 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Nucleoplasm "Plasma membrane" "HPA032040: AB_2674122" "unprognostic (2.42e-2)" "unprognostic (2.07e-2)" "unprognostic (1.14e-1)" "unprognostic (6.29e-3)" "unprognostic (8.30e-2)" "unprognostic (4.10e-1)" "unprognostic (2.40e-5)" "unprognostic (9.30e-2)" "unprognostic (1.17e-1)" "unprognostic (4.94e-2)" "unprognostic (5.72e-2)" "unprognostic (1.15e-2)" "prognostic unfavorable (4.52e-8)" "unprognostic (1.55e-3)" "unprognostic (1.06e-2)" "unprognostic (1.39e-2)" "unprognostic (1.75e-2)" 1.0 2.1 0.8 1.9 1.1 2.8 1.8 1.7 1.4 1.3 1.1 1.6 2.0 1.7 2.7 1.2 1.4 1.3 1.4 0.8 1.0 1.8 2.5 1.2 2.5 1.1 0.9 2.3 2.6 1.0 1.7 1.0 1.0 1.7 2.0 2.5 1.6 1.4 1.2 4.2 1.8 1.4 0.9 1.9 2.0 5.3 1.0 1.9 1.9 0.7 2.5 1.4 0.9 1.2 1.2 3.9 1.9 3.1 1.2 1.0 2.1 2.4 1.2 1.5 3.7 3.5 6.0 2.2 2.4 0.5 2.4 3.9 2.6 2.8 1.9 1.5 2.5 1.0 13.6 1.9 1.1 2.4 2.5 1.9 1.3 2.5 2.4 1.8 1.4 3.8 0.9 3.9 1.1 1.7 3.2 5.1 0.9 1.5 0.6 3.4 2.0 5.1 2.0 1.7 0.9 1.4 1.7 1.0 1.7 1.3 1.8 1.1 1.5 1.8 3.0 1.7 1.9 8.6 4.1 4.4 3.4 2.9 2.6 0.0 0.1 0.1 0.2 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.8 1.1 1.7 1.4 0.8 1.0 1.1 0.9 1.0 0.9 1.0 1.2 0.5 0.0 1.5 0.0 0.5 0.3 0.3 0.7 0.6 0.0 0.6 0.5 1.4 1.5 1.4 0.0 0.0 0.2 0.8 0.6 0.0 0.8 0.0 0.7 0.3 0.5 1.8 3.2 0.0 1.2 0.4 0.6 0.0 0.6 0.0 2.2 0.4 2.0 0.4 0.0 0.0 0.0 0.0 1.0 0.3 0.6 1.2 0.8 1.8 0.0 1.0 0.0 1.0 0.0 0.0 1.0 0.2 0.4 0.9 0.3 0.3 0.3 2.4 0.0 0.0 0.6 0.4 0.6 0.2 0.4 0.9 0.3 0.7 0.8 0.5 0.1 MTPN "GCDP, MYOTROPHIN, V-1" ENSG00000105887 Myotrophin P58546 7 135926760-135977359 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA019735 Approved Approved "Plasma membrane,Cytosol" NA NA 14000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA019735: AB_1858710" "unprognostic (5.97e-2)" "unprognostic (2.53e-2)" "unprognostic (8.52e-2)" "unprognostic (3.62e-3)" "unprognostic (2.20e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (1.19e-4)" "unprognostic (2.06e-3)" "unprognostic (3.30e-2)" "unprognostic (8.11e-2)" "prognostic unfavorable (3.05e-4)" "unprognostic (4.50e-2)" "unprognostic (1.83e-2)" "unprognostic (2.60e-2)" "unprognostic (2.43e-1)" "unprognostic (9.00e-3)" "unprognostic (4.86e-3)" 68.9 49.5 66.7 65.1 75.5 151.1 50.7 41.6 79.4 67.1 45.6 50.5 40.2 65.1 50.9 125.5 62.2 50.5 77.1 79.5 65.0 58.5 49.7 57.8 89.4 77.7 60.0 49.2 23.8 75.9 34.0 61.7 54.0 52.9 55.4 39.9 36.8 51.3 47.6 46.8 46.6 66.1 56.3 79.7 41.2 56.6 65.2 72.5 88.2 48.0 107.8 67.2 58.5 53.3 126.0 90.6 111.5 170.4 160.3 187.2 55.8 189.5 208.0 129.3 137.7 104.5 139.4 229.7 132.7 255.6 188.6 78.9 107.1 161.1 246.1 153.1 84.2 152.9 94.6 77.2 127.3 211.5 213.5 136.5 158.5 152.9 147.7 180.1 205.5 163.6 182.3 138.1 253.2 94.3 208.4 163.0 155.9 121.9 118.9 120.0 83.8 187.7 144.5 103.1 140.6 248.3 157.1 105.8 158.4 102.8 75.4 130.7 215.2 193.5 85.0 192.3 189.7 103.8 160.2 325.9 307.5 185.0 420.2 117.4 75.4 85.2 54.7 105.7 46.0 107.9 33.5 41.7 89.3 125.0 21.5 31.7 180.3 46.0 169.4 82.8 32.6 70.5 66.7 75.5 41.6 79.4 79.5 65.0 77.7 60.0 54.0 56.3 65.2 53.3 110.6 48.1 40.6 0.0 149.8 119.2 58.9 86.8 72.8 0.0 68.6 72.8 82.0 70.1 61.9 69.9 0.0 63.4 131.6 67.1 90.1 69.6 77.8 83.8 153.3 108.5 33.0 91.9 0.0 51.3 73.1 92.4 45.9 131.9 98.6 64.8 87.4 59.2 100.5 0.0 0.0 46.9 46.8 247.5 232.7 28.6 86.3 214.0 101.4 0.0 234.2 0.0 125.7 0.0 0.0 99.9 67.0 123.8 59.2 96.2 52.6 88.3 50.0 0.0 92.1 99.8 79.8 65.8 123.8 143.3 149.0 68.8 86.1 106.5 52.4 106.9 MTSS1 "KIAA0429, MIM, MIMA, MIMB" ENSG00000170873 "MTSS I-BAR domain containing 1" O43312 8 124550784-124728473 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Inhibitory neurons: 208.2;Oligodendrocyte precursor cells: 360.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "non-classical monocyte: 168.3" "Group enriched" "Detected in all" 5 "B-cells: 50.3;monocytes: 168.3" "Cell line enhanced" "Detected in many" "ASC diff: 81.4;HDLM-2: 98.7;HEL: 337.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019613, HPA064003, HPA075540" Approved Supported Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 51: Monocytes - Innate immune response" "Cluster 15: Liver - Metabolism" "Cluster 36: HEL - Hemostasis" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA019613: , HPA064003: , HPA075540: AB_2686756" "unprognostic (1.70e-1)" "unprognostic (4.13e-2)" "unprognostic (9.50e-2)" "unprognostic (1.38e-1)" "unprognostic (3.87e-2)" "unprognostic (7.02e-2)" "unprognostic (4.24e-2)" "unprognostic (1.26e-2)" "unprognostic (2.18e-1)" "unprognostic (2.50e-1)" "unprognostic (8.12e-2)" "unprognostic (1.48e-1)" "prognostic favorable (2.11e-7)" "unprognostic (6.74e-2)" "unprognostic (1.04e-1)" "unprognostic (2.41e-1)" "unprognostic (8.92e-3)" 24.5 36.2 16.8 13.2 23.2 12.5 14.0 46.1 23.4 12.5 22.3 11.0 6.4 8.4 9.9 45.2 12.5 9.2 17.1 16.3 27.7 24.2 72.9 16.5 16.0 27.5 20.6 10.4 28.5 3.7 11.0 35.7 25.3 10.1 9.1 15.0 13.9 6.3 32.3 30.8 7.9 9.6 20.5 34.5 12.0 22.3 26.4 18.4 6.0 24.4 17.2 15.5 24.3 39.5 3.6 1.1 51.6 1.0 81.4 41.7 0.1 2.1 14.2 1.1 0.5 4.8 0.4 1.6 4.9 0.2 0.4 0.8 0.4 29.2 1.1 98.7 1.2 337.8 0.9 27.0 18.4 0.0 34.5 66.4 65.4 15.9 41.0 2.1 31.5 0.3 0.5 0.3 5.6 2.7 0.8 4.0 1.8 54.8 0.4 0.4 0.1 0.5 11.6 11.3 36.3 2.8 7.9 6.3 26.6 2.5 1.3 1.1 16.7 2.7 1.0 0.2 0.7 0.5 0.3 5.4 29.1 0.4 10.7 3.1 13.1 0.1 22.7 88.1 2.6 44.9 4.8 8.7 11.8 50.3 2.2 6.8 2.2 2.2 168.3 0.2 0.5 29.2 16.8 23.2 46.1 23.4 16.3 27.7 27.5 20.6 25.3 20.5 26.4 39.5 33.0 0.0 26.9 15.7 92.0 35.8 81.4 41.2 9.6 0.0 8.0 19.9 34.9 22.8 30.9 66.2 0.0 36.0 51.4 10.7 21.5 17.6 54.2 25.5 0.9 32.2 44.2 17.2 40.4 5.2 2.3 30.5 26.5 9.7 46.3 0.9 70.3 78.1 74.2 0.0 208.2 17.1 61.1 167.1 116.2 62.1 3.7 96.7 26.6 114.3 90.2 0.0 78.2 360.4 178.4 32.6 15.9 4.5 12.6 71.9 1.2 19.9 42.0 0.0 39.5 25.2 17.3 2.5 10.7 86.1 63.4 94.4 22.7 1.8 15.8 59.2 MYH11 "SMHC, SMMHC" ENSG00000133392 "Myosin heavy chain 11" P35749 16 15703135-15857028 "Cancer-related genes, Candidate cardiovascular disease genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Actin-binding, Calmodulin-binding, Motor protein, Muscle protein, Myosin" "Aortic aneurysm, Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 3322.6;seminal vesicle: 1665.5;urinary bladder: 2048.3" "Group enriched" "Detected in many" 8 "Peritubular cells: 1669.7;Sertoli cells: 624.5;Smooth muscle cells: 964.6" "Group enriched" "Detected in many" 5 "prostate cancer: 173.2;stomach cancer: 125.3" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 2.7;RPMI-8226: 1.4;U-698: 7.1" "Low region specificity" "Detected in all" "Region enhanced" "Detected in all" "midbrain: 39.8" "CAB002302, HPA014539, HPA015310" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 23000000 "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 48: Smooth muscle cells - ECM organization" "Plasma membrane, Cytosol" "CAB002302: AB_563902, HPA014539: AB_1234906, HPA015310: AB_1854261" "unprognostic (7.99e-2)" "unprognostic (3.07e-2)" "unprognostic (4.18e-2)" "unprognostic (9.21e-3)" "unprognostic (6.70e-2)" "unprognostic (2.75e-2)" "prognostic favorable (1.10e-5)" "unprognostic (1.41e-2)" "unprognostic (1.87e-1)" "unprognostic (3.44e-2)" "unprognostic (1.28e-1)" "unprognostic (1.14e-1)" "unprognostic (1.19e-3)" "unprognostic (4.06e-2)" "unprognostic (9.53e-2)" "unprognostic (5.00e-2)" "unprognostic (5.45e-3)" 172.9 38.6 5.0 109.1 17.2 0.2 78.4 5.5 14.5 372.3 11.1 3322.6 95.4 1074.6 219.7 759.7 606.1 250.6 74.8 5.3 5.2 27.9 9.2 108.9 9.5 9.0 7.0 144.0 10.7 2.8 11.6 68.2 7.1 762.7 293.2 0.4 83.3 1665.5 41.2 68.5 487.4 1053.2 5.8 46.0 832.5 60.9 7.2 2.9 46.0 34.6 5.3 2048.3 314.2 6.3 0.0 0.1 0.0 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.2 0.0 0.6 0.2 0.0 0.0 0.2 0.0 1.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.1 0.9 0.0 0.2 0.2 7.1 0.1 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.1 0.0 5.0 17.2 5.5 14.5 5.3 5.2 9.0 7.0 7.1 5.8 7.2 6.3 7.6 0.0 1.8 0.0 4.4 13.3 2.1 1.7 5.7 2.7 5.3 122.3 40.5 0.0 1.9 0.0 8.4 0.3 3.4 0.4 0.0 0.2 50.2 4.7 19.5 12.8 1.2 0.8 0.8 0.4 0.3 22.2 0.0 3.4 0.0 27.3 6.4 0.1 1.1 0.0 5.2 0.5 0.0 2.2 17.3 46.2 42.9 2.8 12.4 15.9 3.7 0.3 3.1 1.5 10.7 0.4 0.2 1669.7 2.4 5.6 0.1 0.2 2.5 1.9 624.5 4.3 964.6 3.1 8.8 3.5 18.6 0.0 5.7 34.7 0.4 2.6 MYLK "MLCK, MLCK1, MYLK1, smMLCK" ENSG00000065534 "Myosin light chain kinase" Q15746 3 123610049-123884332 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Actin-binding, Calmodulin-binding, Kinase, Serine/threonine-protein kinase, Transferase" "Aortic aneurysm, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "seminal vesicle: 1700.3;smooth muscle: 2137.7" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 728.5;Hepatocytes: 208.7;Peritubular cells: 690.5;Sertoli cells: 276.1;Smooth muscle cells: 448.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "basophil: 7.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 200.0;BJ hTERT+: 298.2;fHDF/TERT166: 260.2;hTERT-RPE1: 202.7;RPTEC TERT1: 291.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020789, HPA031677, HPA048055" Enhanced Enhanced "Plasma membrane,Actin filaments" NA NA 1500000 "Cluster 34: Basophils - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Actin filaments" "Plasma membrane" "CAB020789: , HPA031677: AB_10794617, HPA048055: AB_2732543" "unprognostic (2.80e-2)" "unprognostic (5.05e-2)" "unprognostic (5.55e-2)" "unprognostic (2.85e-2)" "unprognostic (1.69e-1)" "unprognostic (1.41e-1)" "unprognostic (4.86e-2)" "unprognostic (8.55e-2)" "unprognostic (1.20e-1)" "unprognostic (1.40e-1)" "unprognostic (8.21e-2)" "unprognostic (1.58e-1)" "prognostic unfavorable (2.04e-6)" "unprognostic (5.26e-3)" "unprognostic (9.60e-2)" "unprognostic (3.00e-1)" "prognostic unfavorable (4.46e-4)" 143.6 57.4 37.6 188.7 64.8 3.3 163.4 72.1 42.4 281.3 14.1 551.5 110.9 669.2 232.9 420.6 289.8 250.4 33.6 33.6 46.7 64.4 67.2 85.2 33.6 104.6 64.8 95.9 15.3 11.6 2.6 70.2 99.3 907.6 299.1 13.6 140.1 1700.3 10.0 20.1 125.1 2137.7 55.6 89.5 122.7 50.5 52.2 8.0 22.2 14.9 19.1 505.7 84.8 112.1 14.4 38.4 10.8 7.8 10.8 1.9 4.7 200.0 298.2 137.3 92.1 8.1 7.4 0.6 42.5 260.2 67.0 4.8 5.2 1.8 149.0 0.2 0.7 102.4 0.9 28.9 56.1 0.6 9.8 36.9 3.5 24.4 34.4 202.7 8.9 1.3 1.2 0.5 90.9 1.7 0.2 2.5 12.0 0.5 5.1 13.5 6.8 36.7 291.9 8.5 1.4 6.4 21.8 1.9 3.1 25.0 1.0 0.3 33.4 39.5 13.9 10.3 30.7 3.4 4.2 0.3 104.0 1.0 9.6 7.4 1.6 0.4 0.1 0.2 0.0 0.2 0.0 0.0 3.5 0.1 0.2 0.1 5.0 0.0 0.0 3.3 0.2 20.9 37.6 64.8 72.1 42.4 33.6 46.7 104.6 64.8 99.3 55.6 52.2 112.1 45.9 16.0 38.3 43.4 2.5 20.5 27.2 24.8 1.2 2.9 19.9 728.5 25.2 37.1 5.7 27.6 125.1 0.8 3.5 88.1 3.9 6.0 40.7 45.9 46.6 56.9 11.4 3.2 25.2 3.9 0.8 40.1 3.1 54.4 2.5 3.2 45.3 208.7 4.9 3.3 3.4 3.9 8.2 7.9 37.0 33.8 104.7 20.8 19.6 8.4 1.2 4.7 0.0 5.5 37.0 4.0 18.7 690.5 3.3 8.6 14.2 17.2 17.6 19.9 276.1 5.6 448.7 4.7 4.6 1.3 20.2 2.5 3.2 4.5 4.2 3.7 MYO1C myr2 ENSG00000197879 "Myosin IC" O00159 17 1464186-1492686 "Predicted intracellular proteins, Transporters" "mRNA transport, Protein transport, Translocation, Transport" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001768, HPA005924, CAB037023" Enhanced Enhanced "Nuclear bodies,Plasma membrane" NA NA 3800000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nuclear bodies, Plasma membrane" "CAB037023: AB_477180, HPA001768: AB_1854252, HPA005924: AB_2667469" "unprognostic (3.60e-1)" "unprognostic (4.71e-3)" "unprognostic (2.89e-1)" "unprognostic (2.96e-3)" "unprognostic (1.38e-2)" "unprognostic (1.49e-1)" "unprognostic (1.63e-1)" "prognostic unfavorable (5.22e-4)" "unprognostic (4.65e-2)" "unprognostic (2.00e-2)" "unprognostic (2.48e-1)" "unprognostic (3.07e-2)" "unprognostic (1.99e-2)" "unprognostic (5.02e-2)" "unprognostic (4.66e-2)" "unprognostic (4.93e-2)" "unprognostic (3.47e-2)" 169.3 27.0 12.4 34.4 11.8 4.9 115.9 13.3 12.7 77.4 17.1 104.9 47.4 97.1 21.5 64.7 66.4 46.1 97.5 10.2 14.7 56.8 39.5 87.2 24.1 14.8 11.2 43.6 69.3 34.3 22.9 56.9 14.6 69.9 41.7 2.1 91.7 58.2 49.5 57.7 65.6 65.7 11.9 30.8 76.3 17.1 13.7 21.3 60.6 35.8 25.1 86.3 67.8 10.8 169.8 182.1 19.3 79.5 88.8 87.6 74.2 168.6 138.9 108.7 91.0 122.3 90.7 16.9 118.7 261.1 72.7 139.9 29.2 117.2 56.3 75.2 74.5 16.2 96.4 46.2 131.7 1.6 81.5 68.7 57.3 100.2 57.3 99.5 141.7 10.5 13.1 13.7 93.5 129.5 1.9 1.4 12.4 105.8 34.0 6.9 26.4 30.7 100.5 86.9 7.8 43.0 105.9 152.6 67.4 47.5 125.3 8.7 187.9 156.6 119.1 77.7 147.8 10.7 9.1 7.2 124.7 4.1 138.8 0.1 0.9 0.0 0.9 2.0 0.4 4.8 2.1 0.9 1.1 3.8 0.7 0.4 0.5 0.0 1.7 1.0 1.9 1.5 12.4 11.8 13.3 12.7 10.2 14.7 14.8 11.2 14.6 11.9 13.7 10.8 133.7 125.0 35.9 5.5 20.8 39.8 38.2 27.8 31.9 4.1 44.0 33.0 75.4 48.6 36.3 86.5 0.0 57.8 2.5 159.0 21.5 62.3 17.4 26.3 44.4 78.0 39.5 13.5 2.5 52.0 28.4 51.8 66.3 75.5 12.0 25.4 83.6 38.5 20.0 5.0 3.8 111.8 14.2 14.5 43.4 11.4 42.3 16.7 64.0 15.0 20.3 5.6 0.0 2.5 1.0 92.8 88.7 48.5 12.8 64.7 92.8 15.4 12.9 2.1 118.3 37.7 90.6 9.4 7.5 39.5 42.6 47.6 10.0 10.6 88.1 39.2 MYO1G HA-2 ENSG00000136286 "Myosin IG" B0I1T2 7 44962662-44979088 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Actin-binding, Calmodulin-binding, Motor protein, Myosin" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 43.6;lymphoid tissue: 27.2" "Cell type enhanced" "Detected in many" "dendritic cells: 81.3;Langerhans cells: 65.1;Macrophages: 74.2;monocytes: 392.2;NK-cells: 252.4;T-cells: 87.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in some" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 52.6;HEL: 64.1;HL-60: 39.9;JURKAT: 85.9;MOLT-4: 97.3;NB-4: 52.1;THP-1: 68.6;U-937: 57.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA021252 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 66: Lymphoid tissue - Immune response regulation" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 3: Monocytes - Immune response regulation" "Plasma membrane" Nucleoplasm "HPA021252: AB_1854254" "unprognostic (2.74e-2)" "prognostic favorable (8.26e-4)" "unprognostic (5.20e-3)" "unprognostic (9.91e-3)" "unprognostic (1.27e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (1.35e-1)" "unprognostic (4.54e-3)" "unprognostic (6.47e-2)" "unprognostic (6.40e-2)" "unprognostic (6.24e-2)" "prognostic unfavorable (8.71e-8)" "unprognostic (3.20e-1)" "unprognostic (2.04e-1)" "unprognostic (1.85e-1)" "unprognostic (7.92e-2)" 2.2 0.8 0.4 16.6 0.3 43.6 1.0 0.3 0.6 0.8 0.3 2.0 3.3 0.7 0.3 1.5 1.2 3.5 0.9 0.3 1.0 0.9 1.3 12.0 25.1 1.4 0.7 0.3 0.7 0.1 0.5 1.2 0.6 1.1 1.8 0.0 2.3 0.7 0.3 0.9 7.8 2.8 0.6 19.0 3.3 0.4 1.6 27.2 1.6 0.4 14.8 6.1 0.9 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 52.6 0.0 64.1 2.7 0.0 0.0 39.9 0.6 0.0 0.0 0.0 0.0 0.0 0.0 85.9 0.0 0.0 0.0 0.0 97.3 52.1 0.0 0.0 0.0 18.5 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.1 0.0 0.0 68.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 15.7 0.0 57.3 0.0 41.5 58.3 18.5 61.5 95.5 38.4 27.7 40.5 55.6 42.7 18.9 14.1 29.6 6.0 23.9 129.8 4.5 79.9 79.9 0.4 0.3 0.3 0.6 0.3 1.0 1.4 0.7 0.6 0.6 1.6 0.8 0.9 3.2 7.7 0.0 55.7 2.8 0.4 0.0 0.0 0.2 1.2 1.3 1.1 1.5 1.3 0.0 0.0 0.2 81.3 0.2 0.0 0.3 0.6 0.3 0.5 1.0 0.0 6.3 0.1 1.1 0.3 2.3 2.0 0.6 30.4 0.4 2.2 1.4 10.5 3.3 0.0 0.2 0.0 58.7 65.1 1.6 0.0 74.2 3.6 0.0 392.2 0.3 252.4 0.5 0.0 0.2 0.1 0.4 33.4 0.4 0.0 0.6 0.7 0.2 6.6 2.0 1.4 3.8 1.2 0.2 1.7 0.1 87.1 1.2 0.1 0.2 MYOF "FER1L3, KIAA1207" ENSG00000138119 Myoferlin Q9NZM1 10 93306429-93482334 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 123.4;Pancreatic endocrine cells: 153.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "intermediate monocyte: 20.4;non-classical monocyte: 26.6" "Group enriched" "Detected in many" 57 "dendritic cells: 8.1;monocytes: 26.6" "Cell line enhanced" "Detected in many" "BJ hTERT+: 452.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA014245 Enhanced Supported "Vesicles,Plasma membrane" NA NA 190000 "Cluster 51: Monocytes - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Vesicles "Plasma membrane" "HPA014245: AB_1848495" "unprognostic (3.41e-2)" "unprognostic (3.85e-1)" "unprognostic (2.88e-2)" "unprognostic (7.44e-2)" "unprognostic (3.50e-2)" "unprognostic (8.57e-3)" "unprognostic (3.48e-2)" "unprognostic (7.75e-2)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (1.40e-4)" "unprognostic (1.55e-1)" "unprognostic (5.74e-3)" "unprognostic (1.87e-1)" "unprognostic (1.94e-2)" "unprognostic (9.17e-2)" "unprognostic (9.18e-2)" 31.7 8.1 2.9 20.6 4.1 1.5 43.3 5.0 2.5 56.4 37.4 22.4 5.3 27.5 7.1 36.4 36.9 26.6 13.8 3.4 4.1 10.9 2.9 32.2 4.4 8.9 6.8 9.8 5.9 23.8 3.8 55.2 8.1 27.5 29.3 0.9 19.7 31.4 3.6 56.1 9.0 44.3 6.2 6.5 13.4 2.2 5.4 5.1 35.7 6.2 9.1 62.0 29.4 6.2 228.9 206.3 21.4 14.6 159.4 318.4 62.0 190.3 452.7 110.1 109.2 51.1 177.1 0.0 76.9 353.7 116.2 350.0 1.8 204.7 82.6 1.4 0.9 0.0 80.8 2.1 55.2 0.0 0.2 183.0 71.6 77.7 323.8 289.4 299.7 0.0 0.0 0.5 275.6 39.4 0.1 0.9 1.6 72.0 171.6 0.0 15.8 0.1 314.3 281.5 0.1 0.0 130.4 29.7 46.1 83.1 141.5 4.7 378.5 167.3 11.8 111.3 113.9 0.2 0.3 0.3 128.2 2.6 201.0 0.0 5.4 0.0 0.0 20.4 0.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.3 0.0 26.6 2.8 0.2 1.6 2.9 4.1 5.0 2.5 3.4 4.1 8.9 6.8 8.1 6.2 5.4 6.2 42.5 60.9 52.5 1.6 1.2 23.7 63.0 101.4 39.3 0.1 48.4 34.3 9.2 14.3 91.5 22.0 0.0 56.6 3.8 74.1 1.9 54.8 0.6 50.9 45.9 28.8 1.8 0.0 2.7 33.7 23.7 38.1 23.0 123.4 1.3 1.7 35.7 0.4 22.9 0.0 0.8 29.6 42.7 29.2 20.2 0.6 5.9 28.5 8.8 60.0 12.8 0.1 0.0 2.0 0.7 153.7 22.2 9.1 0.8 86.7 0.6 1.5 60.7 0.8 6.6 15.9 39.6 0.1 0.3 53.4 30.7 51.2 1.9 8.3 18.7 100.7 NAP1L2 "BPX, MGC26243" ENSG00000186462 "Nucleosome assembly protein 1 like 2" Q9ULW6 X 73212299-73214851 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 60.4" "Cell type enhanced" "Detected in many" "Bipolar cells: 24.4;Excitatory neurons: 34.3;Horizontal cells: 18.5;Inhibitory neurons: 33.7" "Cancer enhanced" "Detected in many" "prostate cancer: 7.8" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "EFO-21: 16.6;Karpas-707: 14.1;NTERA-2: 18.1;U-2197: 14.6;U-266/84: 31.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA054050, HPA057065" Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 56: Bipolar cells - Visual perception" "Plasma membrane, Cytosol" "HPA054050: AB_2682357, HPA057065: AB_2797258" "unprognostic (1.12e-1)" "unprognostic (6.64e-5)" "unprognostic (4.22e-2)" "unprognostic (9.64e-4)" "unprognostic (1.78e-1)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (8.51e-3)" "unprognostic (1.76e-2)" "unprognostic (2.66e-1)" "prognostic favorable (5.41e-4)" "unprognostic (1.53e-2)" "unprognostic (1.54e-2)" "unprognostic (6.95e-4)" "unprognostic (1.07e-1)" "unprognostic (1.19e-1)" "unprognostic (2.45e-2)" 2.1 6.0 22.7 2.2 24.4 0.5 3.1 28.4 60.4 4.2 4.6 3.4 0.9 5.1 8.2 2.6 4.0 2.3 7.9 28.8 27.0 8.3 1.0 2.3 3.2 18.5 15.4 8.9 2.5 12.1 14.5 0.0 17.9 11.0 2.9 19.1 3.2 5.8 1.3 5.2 2.2 4.7 12.1 4.2 2.2 2.1 15.7 1.7 8.5 2.9 1.6 2.9 2.6 25.7 0.0 4.8 0.1 9.4 0.6 0.0 0.0 0.1 0.1 0.0 0.0 1.0 0.3 0.0 16.6 0.0 8.9 1.0 3.4 0.4 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.8 0.4 1.3 0.2 2.4 0.1 0.3 6.6 0.4 14.1 0.0 1.7 5.9 0.0 18.1 0.0 8.4 0.0 0.0 0.4 2.0 0.0 0.0 0.0 0.0 1.1 0.0 3.5 1.8 0.0 0.1 0.0 10.3 14.6 1.2 6.6 31.3 0.0 0.6 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.5 0.3 1.2 0.8 0.0 0.0 0.6 1.3 0.0 0.5 0.0 0.0 1.0 0.5 22.7 24.4 28.4 60.4 28.8 27.0 18.5 15.4 17.9 12.1 15.7 25.7 1.0 0.0 3.0 8.5 0.9 6.4 6.2 1.0 8.0 24.4 0.7 2.9 11.1 2.8 0.8 12.9 0.0 0.0 2.9 1.8 13.7 1.1 0.0 0.0 0.2 3.1 7.2 0.0 34.3 0.2 0.0 4.1 1.1 0.1 4.5 0.2 3.6 0.7 0.1 18.5 33.7 0.4 0.0 0.3 0.0 0.4 0.3 0.1 0.0 9.4 0.0 13.7 0.0 9.5 9.1 0.8 0.5 0.4 1.9 3.3 0.0 3.3 0.0 9.9 0.0 5.5 4.0 0.2 0.1 2.6 3.0 0.0 3.5 0.2 0.5 1.0 NCAM1 "CD56, NCAM" ENSG00000149294 "Neural cell adhesion molecule 1" P13591 11 112961247-113278436 "Cancer-related genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion, Host-virus interaction" "Host cell receptor for virus entry, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 290.1;heart muscle: 145.5" "Cell type enhanced" "Detected in many" "Astrocytes: 530.8;Excitatory neurons: 461.4;Inhibitory neurons: 441.2;Oligodendrocyte precursor cells: 939.0;Oligodendrocytes: 1013.5" "Cancer enriched" "Detected in many" 8 "glioma: 31.0" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 15 "NK-cell: 53.7" "Lineage enriched" "Detected in many" 15 "NK-cells: 53.7" "Cell line enhanced" "Detected in many" "HEL: 61.3;RH-30: 132.5;SCLC-21H: 107.4;SH-SY5Y: 52.7;U-138 MG: 72.8;WM-115: 79.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000142, CAB018071, HPA039835" Enhanced Enhanced "Plasma membrane,Cytosol" "Secreted in other tissues" NA NA 1200000 2300000000 "Cluster 48: NK-cells - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" Cytosol "CAB000142: , CAB018071: AB_627129, HPA039835: AB_2676705" "unprognostic (7.04e-2)" "unprognostic (1.16e-1)" "unprognostic (2.77e-2)" "unprognostic (2.18e-2)" "unprognostic (2.91e-1)" "unprognostic (1.74e-3)" "unprognostic (2.82e-1)" "unprognostic (4.42e-3)" "unprognostic (2.13e-1)" "unprognostic (1.63e-2)" "prognostic favorable (9.11e-6)" "unprognostic (8.13e-2)" "prognostic unfavorable (8.20e-4)" "unprognostic (2.97e-2)" "unprognostic (2.24e-1)" "unprognostic (3.75e-2)" "unprognostic (5.82e-5)" 4.6 65.7 124.0 3.9 169.1 1.5 2.7 118.1 140.3 35.1 0.0 47.8 4.6 62.7 3.5 7.0 40.4 4.8 145.5 135.6 179.1 3.2 2.9 1.8 1.3 140.4 134.2 43.8 2.6 0.0 22.2 0.5 147.4 14.9 6.6 117.7 3.6 17.7 31.2 2.1 18.3 46.9 129.7 4.7 23.0 5.0 137.0 0.4 30.2 29.5 1.0 34.8 24.3 290.1 0.1 0.0 20.8 0.3 0.2 0.5 0.3 1.0 0.0 0.7 1.2 0.3 0.3 3.1 18.2 20.1 0.8 0.3 0.1 0.0 0.0 0.4 12.1 61.3 0.1 0.0 2.1 0.0 9.5 12.4 0.1 0.1 18.6 0.1 0.0 0.1 0.0 1.0 20.8 0.0 0.2 5.2 1.8 0.0 0.4 0.1 132.5 10.0 0.0 0.0 107.4 52.7 0.1 0.5 0.1 2.0 0.2 0.8 0.2 72.8 33.4 0.3 31.8 0.1 0.5 0.1 8.3 28.4 79.0 0.0 0.2 0.0 3.6 0.0 1.2 0.0 0.1 0.5 0.1 0.0 0.0 1.4 0.7 53.7 0.0 0.0 0.2 1.9 124.0 169.1 118.1 140.3 135.6 179.1 140.4 134.2 147.4 129.7 137.0 290.1 13.7 0.0 0.0 530.8 0.4 1.7 0.5 0.0 0.0 123.5 5.7 0.6 131.7 0.0 0.0 0.0 37.5 0.6 27.7 0.1 1.9 18.3 6.7 0.3 2.4 2.8 5.4 0.0 461.4 0.0 0.2 12.8 5.1 0.5 1.3 11.7 7.1 0.7 0.4 175.0 441.2 0.0 8.2 4.7 3.8 5.9 15.2 1.8 0.0 35.6 1.2 216.6 59.8 939.0 1013.5 1.3 0.0 10.1 5.6 0.4 0.0 0.2 0.7 98.0 0.0 107.5 4.8 1.0 2.8 0.4 1.7 0.1 13.4 5.6 0.0 0.2 NCAM2 "MGC51008, NCAM21" ENSG00000154654 "Neural cell adhesion molecule 2" O15394 21 20998409-21543329 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 12.0;brain: 26.0" "Group enriched" "Detected in some" 19 "Astrocytes: 713.0;Excitatory neurons: 866.5;Inhibitory neurons: 909.2;Oligodendrocyte precursor cells: 1729.1;Oligodendrocytes: 1526.6" "Group enriched" "Detected in some" 4 "breast cancer: 2.6;glioma: 5.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "T-47d: 92.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030900, HPA030901" Enhanced Supported Supported "Nuclear bodies,Plasma membrane" No No 120000000 "Cluster 65: Brain - Ion transport" "Cluster 6: T47d - Mammary gland" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nuclear bodies, Plasma membrane" "HPA030900: AB_10602037, HPA030901: AB_2673650" "unprognostic (9.70e-2)" "unprognostic (1.08e-1)" "unprognostic (1.47e-1)" "unprognostic (2.54e-2)" "unprognostic (1.85e-1)" "unprognostic (1.81e-1)" "unprognostic (1.37e-2)" "unprognostic (3.01e-2)" "unprognostic (5.90e-2)" "unprognostic (1.62e-1)" "unprognostic (1.31e-1)" "unprognostic (5.61e-1)" "unprognostic (3.07e-4)" "unprognostic (2.47e-4)" "unprognostic (1.62e-1)" "unprognostic (8.05e-2)" "unprognostic (1.35e-3)" 0.7 12.0 14.1 0.9 19.0 0.0 1.6 8.4 17.5 1.6 0.0 2.0 0.2 1.0 0.5 0.5 0.6 1.2 2.0 21.3 22.7 0.2 6.7 2.8 0.1 8.6 14.4 0.3 0.2 0.6 0.8 0.5 8.8 0.9 1.0 1.2 0.7 1.0 0.4 0.8 0.7 1.4 8.8 0.8 0.6 6.3 26.0 0.1 0.3 0.8 0.2 0.6 1.2 21.6 0.0 0.0 0.5 0.0 4.6 4.7 0.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.8 0.1 0.0 0.0 0.0 0.5 1.3 0.0 0.5 1.3 0.0 2.2 0.0 0.1 11.3 0.0 3.5 0.0 0.4 0.0 0.0 11.4 2.4 0.2 15.4 0.2 0.0 0.4 0.0 0.0 1.0 0.0 4.7 0.0 0.0 0.0 5.3 0.0 0.8 0.6 0.1 92.1 7.2 0.0 1.3 0.9 0.1 0.0 0.6 0.0 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.1 19.0 8.4 17.5 21.3 22.7 8.6 14.4 8.8 8.8 26.0 21.6 0.4 3.2 1.3 713.0 0.1 0.5 0.3 0.0 0.0 1.0 2.0 1.4 1.8 0.0 0.0 0.0 0.0 1.7 0.3 0.0 0.0 0.0 57.6 0.3 6.1 0.4 0.0 0.0 866.5 0.0 0.4 4.8 0.0 0.2 0.0 0.2 2.2 0.0 0.3 0.0 909.2 0.0 0.0 0.0 0.3 24.7 0.9 0.1 1.8 30.9 0.0 1.0 0.0 1729.1 1526.6 0.0 0.0 0.4 0.0 0.7 0.0 0.1 0.0 0.1 0.0 2.4 1.6 3.7 9.6 0.1 0.1 0.3 0.2 1.9 0.0 0.2 NCK1 "NCK, NCKalpha" ENSG00000158092 "NCK adaptor protein 1" P16333 3 136862208-136951606 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Basal respiratory cells: 225.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005063, HPA030766" Supported Approved "Plasma membrane,Cytosol" NA NA 17000 "Cluster 38: Basophils - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "CAB005063: AB_562169, HPA030766: AB_2673602" "unprognostic (7.47e-2)" "unprognostic (2.07e-1)" "unprognostic (3.98e-2)" "unprognostic (3.03e-2)" "unprognostic (1.06e-2)" "unprognostic (8.77e-3)" "unprognostic (4.24e-3)" "unprognostic (8.30e-2)" "unprognostic (9.31e-2)" "unprognostic (1.22e-1)" "prognostic unfavorable (9.14e-5)" "unprognostic (5.96e-2)" "prognostic unfavorable (1.08e-4)" "unprognostic (1.64e-1)" "unprognostic (2.58e-1)" "unprognostic (1.66e-1)" "unprognostic (4.17e-2)" 34.4 17.9 12.8 26.2 13.0 32.0 28.6 17.0 15.3 27.3 20.4 27.7 15.3 23.7 17.0 38.7 20.4 20.1 20.2 12.9 14.6 16.1 30.9 27.0 41.8 14.2 14.3 23.3 17.2 24.2 13.7 30.7 14.2 21.4 27.8 18.4 24.6 19.2 27.5 30.2 15.8 23.6 12.8 28.8 18.4 19.6 13.9 52.9 26.9 29.1 44.5 29.3 36.2 15.8 50.1 22.0 28.4 23.4 65.3 62.7 31.5 36.6 65.3 41.8 43.4 32.3 49.9 49.0 74.9 43.0 54.5 37.9 40.3 37.1 54.3 35.7 16.3 43.0 31.1 25.4 106.0 31.3 28.2 57.4 47.3 40.8 80.0 41.9 64.4 46.1 26.3 42.7 44.2 28.2 71.8 25.3 26.8 45.6 27.6 37.6 26.4 47.6 38.9 34.4 19.8 19.2 66.5 28.1 62.2 34.2 42.0 33.8 32.5 27.1 17.1 38.8 21.3 42.2 36.6 62.5 27.8 27.6 29.3 61.1 22.3 24.7 32.8 50.5 33.6 13.9 25.7 33.7 24.4 14.2 20.8 24.5 12.8 21.6 26.4 9.4 27.6 23.6 12.8 13.0 17.0 15.3 12.9 14.6 14.2 14.3 14.2 12.8 13.9 15.8 58.6 9.6 15.9 25.5 41.6 74.8 77.1 225.1 79.6 20.1 23.7 19.9 11.1 27.1 144.3 9.2 6.2 45.4 54.0 29.6 15.6 50.4 11.6 27.9 31.9 61.4 13.8 17.5 28.6 27.3 52.7 42.8 9.2 31.2 9.5 14.9 31.8 37.5 48.3 25.2 37.9 17.7 46.8 36.6 62.8 8.9 44.1 38.0 42.7 70.3 49.6 20.2 88.6 42.7 36.9 37.9 25.3 26.7 36.2 98.0 15.6 23.9 75.7 14.6 13.1 24.9 32.1 55.2 36.6 66.1 83.3 61.0 70.4 21.8 18.8 142.9 NCKAP1L HEM1 ENSG00000123338 "NCK associated protein 1 like" P55160 12 54497752-54548243 "Plasma proteins, Predicted membrane proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 44.9" "Cell type enhanced" "Detected in many" "B-cells: 66.2;dendritic cells: 92.3;Hofbauer cells: 115.5;Kupffer cells: 175.1;Macrophages: 108.1;monocytes: 153.2;NK-cells: 113.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HL-60: 112.4;HMC-1: 112.4;NB-4: 82.6;REH: 59.1;THP-1: 121.3;U-937: 70.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039490, HPA040772" Approved Uncertain "Plasma membrane,Cytosol" NA NA 33000 "Cluster 51: Monocytes - Innate immune response" "Cluster 16: Immune cells - Immune response" "Cluster 43: THP-1 - Innate immune response" "Cluster 4: Macrophages - Innate immune response" Cytosol "Plasma membrane" "HPA039490: AB_2676540, HPA040772: AB_2677129" "unprognostic (4.54e-2)" "unprognostic (5.20e-3)" "unprognostic (1.61e-2)" "unprognostic (1.22e-3)" "unprognostic (9.29e-2)" "unprognostic (1.01e-2)" "unprognostic (3.69e-1)" "unprognostic (2.95e-2)" "unprognostic (6.53e-3)" "unprognostic (4.80e-1)" "unprognostic (1.76e-1)" "unprognostic (2.08e-1)" "unprognostic (1.54e-3)" "unprognostic (2.57e-1)" "unprognostic (2.76e-2)" "unprognostic (3.63e-2)" "unprognostic (4.74e-2)" 9.7 4.6 3.3 34.8 4.0 28.4 4.7 3.6 3.7 4.0 4.0 19.7 5.8 2.5 1.3 6.1 3.4 7.3 2.6 2.9 3.7 2.3 7.1 20.2 42.5 6.9 4.8 1.8 1.6 4.0 1.5 11.0 6.5 4.7 9.7 0.4 3.5 5.2 1.2 2.3 18.1 10.3 5.4 44.9 6.7 1.2 6.8 37.4 2.2 2.0 43.4 27.9 2.8 8.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 47.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 40.4 0.3 47.9 0.0 0.0 0.0 112.4 112.4 0.0 0.0 0.0 0.0 0.0 0.7 40.1 7.7 43.7 0.0 0.0 47.9 82.6 0.1 0.0 0.0 59.1 0.2 47.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 121.3 0.0 0.2 0.0 0.1 0.1 2.4 2.9 38.4 0.2 70.4 0.0 31.7 68.6 55.0 31.7 103.9 26.2 30.2 28.3 32.7 72.0 28.8 17.9 26.4 16.9 36.1 121.3 40.8 45.1 65.1 3.3 4.0 3.6 3.7 2.9 3.7 6.9 4.8 6.5 5.4 6.8 8.4 1.0 0.0 11.6 0.3 66.2 1.3 0.3 0.0 0.0 1.3 0.6 2.2 1.5 4.3 1.8 0.0 0.0 0.7 92.3 0.2 0.0 0.1 0.9 0.2 0.3 3.6 0.0 22.1 0.8 0.4 1.0 2.7 2.0 0.3 56.3 0.1 7.5 1.4 115.5 0.0 0.5 0.0 0.0 175.1 28.5 2.3 1.2 108.1 5.4 42.2 153.2 0.4 113.3 0.5 0.0 0.0 0.1 0.0 40.0 0.1 0.0 0.3 0.7 0.9 0.0 0.8 1.3 0.9 1.6 0.1 0.6 1.4 59.7 0.2 0.0 0.2 NEXN "NELIN, nexilin" ENSG00000162614 "Nexilin F-actin binding protein" Q0ZGT2 1 77888513-77943895 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Cardiomyopathy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "heart muscle: 404.8;skeletal muscle: 676.9;tongue: 548.9" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 2329.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ: 152.2;LHCN-M2: 135.1;RH-30: 108.5" "Region enhanced" "Detected in all" "basal ganglia: 40.4" "Group enriched" "Detected in all" 4 "basal ganglia: 9.0;midbrain: 13.4;pons: 10.0;thalamus: 25.2" "HPA011185, HPA011904" Approved Supported "Plasma membrane,Actin filaments" NA NA 2900000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Actin filaments" "HPA011185: AB_1854409, HPA011904: " "unprognostic (9.73e-2)" "unprognostic (6.72e-2)" "prognostic unfavorable (5.60e-4)" "unprognostic (1.72e-2)" "unprognostic (1.11e-1)" "unprognostic (1.42e-2)" "unprognostic (1.62e-2)" "unprognostic (1.09e-1)" "unprognostic (3.03e-2)" "unprognostic (2.22e-1)" "unprognostic (1.46e-1)" "unprognostic (3.25e-1)" "unprognostic (5.41e-2)" "unprognostic (5.60e-2)" "unprognostic (2.48e-1)" "unprognostic (9.65e-3)" "unprognostic (3.68e-2)" 42.8 22.3 2.3 24.5 3.1 0.6 16.2 1.7 1.6 21.9 2.5 89.2 10.2 79.0 10.7 49.4 47.5 28.7 404.8 1.3 1.8 8.0 5.6 25.2 5.6 1.4 3.3 15.2 10.0 1.5 1.4 10.6 1.5 62.5 15.7 0.6 11.5 69.8 676.9 6.8 26.7 70.6 1.2 8.6 44.1 5.7 4.7 2.1 10.3 548.9 1.8 49.7 19.5 1.7 26.0 1.5 4.5 0.2 79.5 75.3 12.3 152.2 65.5 29.8 20.2 4.6 0.2 0.0 8.6 54.7 34.4 3.4 3.3 14.3 53.3 0.7 3.4 6.2 7.5 1.5 59.3 1.3 0.2 56.6 3.3 40.7 23.8 65.2 22.8 6.0 0.3 0.0 135.1 0.0 29.9 1.8 23.8 0.0 18.6 24.3 108.5 0.2 35.5 1.2 0.1 1.1 13.3 0.0 1.0 29.9 0.0 3.5 23.4 71.7 53.6 31.2 76.1 0.2 0.2 0.1 4.0 2.8 0.2 0.0 1.7 0.0 0.2 1.0 0.0 0.7 0.1 0.2 0.9 0.5 0.3 0.1 1.4 0.3 0.8 0.6 0.0 3.6 2.3 3.1 1.7 1.6 1.3 1.8 1.4 3.3 1.5 1.2 4.7 1.7 8.3 105.8 4.9 11.4 2.1 1.8 0.9 4.6 1.2 2.7 1.4 33.1 2329.6 0.0 5.4 0.0 4.2 0.8 4.1 0.4 1.9 15.3 24.0 2.6 24.2 17.4 0.0 1.7 26.6 32.4 4.0 93.2 1.1 3.2 1.3 29.7 38.6 1.5 1.2 1.7 27.6 0.5 0.0 4.4 2.2 9.0 73.3 44.9 0.0 16.9 5.8 0.7 0.0 24.6 27.3 21.8 0.1 346.1 0.3 1.3 5.3 0.7 0.4 3.8 216.9 70.4 177.2 0.7 3.6 0.8 0.9 0.3 2.3 13.0 2.1 0.4 NFAM1 CNAIP ENSG00000235568 "NFAT activating protein with ITAM motif 1" Q8NET5 22 42380407-42432403 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 30.9;lymphoid tissue: 19.9" "Cell type enhanced" "Detected in some" "granulocytes: 11.4;Hofbauer cells: 17.0;Kupffer cells: 53.9;Macrophages: 27.2;monocytes: 44.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 90.4" "Group enriched" "Detected in many" 4 "granulocytes: 90.4;monocytes: 48.2" "Cell line enriched" "Detected in some" 4 "THP-1: 37.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in some" HPA031812 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 43: THP-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA031812: AB_10603121" "unprognostic (9.77e-3)" "unprognostic (2.77e-3)" "unprognostic (8.21e-2)" "prognostic favorable (6.16e-4)" "unprognostic (4.83e-2)" "unprognostic (8.76e-3)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "unprognostic (9.12e-3)" "unprognostic (9.97e-2)" "unprognostic (1.13e-1)" "unprognostic (1.00e-1)" "unprognostic (8.12e-3)" "unprognostic (1.75e-1)" "unprognostic (4.42e-2)" "unprognostic (2.71e-2)" "unprognostic (1.91e-1)" 6.3 1.9 1.5 12.4 1.9 30.9 1.1 1.5 2.2 1.8 2.0 1.5 1.3 0.6 0.6 1.3 2.0 2.3 1.3 1.8 2.4 1.2 2.3 7.5 5.5 3.1 2.2 0.3 0.8 0.3 0.6 2.9 2.9 0.9 1.2 0.1 0.8 1.4 0.4 1.4 2.3 2.9 2.3 19.9 1.1 0.7 2.9 2.1 0.7 1.5 2.1 3.1 0.7 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.6 0.0 0.0 0.1 0.0 0.0 0.0 3.1 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 8.8 0.2 0.0 0.0 0.2 0.0 0.0 0.4 0.1 5.8 0.0 0.0 0.1 0.0 0.4 0.0 37.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 4.4 0.0 0.3 48.2 2.8 0.1 32.5 0.2 0.0 0.1 0.0 16.5 0.1 0.0 0.0 90.4 0.0 31.1 0.3 0.0 25.4 1.5 1.9 1.5 2.2 1.8 2.4 3.1 2.2 2.9 2.3 2.9 3.0 0.4 0.0 3.7 0.0 0.5 0.9 0.7 0.9 0.6 0.2 0.4 0.0 0.6 1.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.3 2.8 0.4 0.2 0.5 1.2 0.0 0.7 0.2 0.1 0.5 0.0 0.3 11.4 0.0 0.7 0.6 17.0 0.0 0.6 0.0 0.0 53.9 8.2 5.6 0.3 27.2 0.0 8.4 44.6 0.0 0.0 2.0 0.5 0.0 0.0 0.4 0.1 0.1 0.0 0.1 0.1 0.5 0.0 0.5 0.5 0.8 0.7 0.0 1.0 0.3 1.3 0.4 0.0 0.5 NGEF ARHGEF27 ENSG00000066248 "Neuronal guanine nucleotide exchange factor" Q8N5V2 2 232878701-233013256 "Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "adrenal gland: 56.2;brain: 129.6" "Cell type enhanced" "Detected in many" "Distal enterocytes: 38.0;Excitatory neurons: 105.9;Proximal enterocytes: 66.7" "Cancer enhanced" "Detected in many" "testis cancer: 22.5" "Region enhanced" "Detected in many" "basal ganglia: 129.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 53.9;HDLM-2: 45.3;HeLa: 21.6;PC-3: 57.0;T-47d: 32.2" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "basal ganglia: 167.6;cerebral cortex: 133.8;hippocampal formation: 73.0" HPA008160 Approved Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA008160: AB_1854450" "unprognostic (3.92e-1)" "unprognostic (1.78e-1)" "unprognostic (4.12e-3)" "unprognostic (1.66e-1)" "unprognostic (5.25e-2)" "unprognostic (5.46e-2)" "unprognostic (1.15e-1)" "unprognostic (2.39e-3)" "unprognostic (5.41e-3)" "unprognostic (2.58e-1)" "unprognostic (6.94e-3)" "unprognostic (1.24e-1)" "unprognostic (6.16e-2)" "unprognostic (2.31e-1)" "unprognostic (1.10e-1)" "unprognostic (2.80e-2)" "unprognostic (2.74e-1)" 1.1 56.2 16.3 2.2 129.6 0.1 1.9 0.0 59.4 4.1 0.0 14.2 42.7 5.0 4.1 10.3 4.8 3.1 2.2 19.8 0.0 7.0 35.5 0.7 0.2 0.0 0.0 2.0 6.0 11.9 2.7 0.3 0.0 1.8 10.5 1.4 2.0 0.7 0.9 30.3 31.3 6.7 0.0 0.4 10.7 3.7 0.2 0.0 0.9 0.7 0.3 1.8 5.2 29.4 53.9 15.4 0.6 0.2 0.2 8.2 0.9 0.9 0.1 0.4 0.0 0.7 5.2 0.0 15.2 10.9 5.5 6.9 11.6 3.0 0.4 45.3 3.8 0.1 21.6 16.7 0.2 0.0 0.3 0.0 0.2 3.5 0.6 0.2 1.9 0.2 0.2 0.2 0.5 4.0 0.0 0.1 1.3 0.2 57.0 0.0 0.0 0.1 1.0 1.4 1.9 0.4 6.6 3.3 0.1 2.0 32.2 0.4 0.0 0.5 4.5 0.3 1.0 0.5 0.2 0.0 3.8 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.3 129.6 0.0 59.4 19.8 0.0 0.0 0.0 0.0 0.0 0.2 29.4 0.0 0.0 0.0 10.4 0.0 9.9 1.2 1.2 2.8 0.3 2.1 1.4 2.4 4.3 0.5 0.0 0.0 0.1 0.0 38.0 0.0 3.9 0.7 9.1 0.9 0.4 4.9 0.0 105.9 10.5 0.3 0.7 17.3 2.0 0.0 0.3 0.4 20.4 0.1 1.7 12.8 14.6 0.0 0.3 0.6 2.0 0.0 0.3 1.8 6.5 0.0 5.5 0.0 4.5 6.0 12.1 23.5 1.2 0.1 0.5 66.7 9.8 2.5 0.2 0.0 0.2 0.3 1.1 0.8 3.8 7.5 0.0 0.2 0.5 20.2 1.1 NGFR "CD271, p75NTR, TNFRSF16" ENSG00000064300 "Nerve growth factor receptor" P08138 17 49495293-49515008 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins, RAS pathway related proteins" "Apoptosis, Biological rhythms, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 63.6" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 52.4;Basal squamous epithelial cells: 36.5;Ionocytes: 89.5;Leydig cells: 96.0;Muller glia cells: 151.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 8 "plasmacytoid DC: 1.2" "Lineage enriched" "Detected in single" 8 "dendritic cells: 1.2" "Group enriched" "Detected in some" 7 "RH-30: 200.1;WM-115: 225.3" "Low region specificity" "Detected in many" "Region enhanced" "Detected in many" "basal ganglia: 10.1" "CAB000143, CAB001995, HPA004765" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 490000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "CAB000143: , CAB001995: , HPA004765: AB_1079233" "unprognostic (6.25e-3)" "unprognostic (1.06e-3)" "unprognostic (3.39e-3)" "unprognostic (6.67e-2)" "unprognostic (1.46e-2)" "unprognostic (2.26e-1)" "unprognostic (8.22e-2)" "unprognostic (4.94e-2)" "unprognostic (1.08e-2)" "unprognostic (4.10e-3)" "unprognostic (1.85e-2)" "unprognostic (1.25e-1)" "unprognostic (3.37e-2)" "unprognostic (4.01e-2)" "unprognostic (3.06e-2)" "unprognostic (2.77e-3)" "prognostic unfavorable (3.40e-4)" 36.8 20.7 4.1 8.2 12.1 0.4 20.3 17.3 63.6 13.1 1.4 16.8 2.4 12.0 4.0 6.5 20.2 9.4 40.9 3.2 25.1 8.0 22.8 2.9 5.0 16.9 15.2 4.1 10.9 1.3 10.5 14.7 15.1 19.1 2.4 45.1 21.2 7.6 4.8 15.9 8.0 8.2 10.9 23.0 7.9 7.7 17.2 2.0 28.9 1.3 3.9 15.3 13.2 27.8 0.0 0.1 6.3 10.2 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.2 0.1 0.0 2.1 0.1 3.4 4.8 1.5 4.6 0.0 0.4 0.7 0.4 0.0 3.8 0.4 0.3 0.3 20.9 0.3 0.6 1.5 0.1 0.0 0.0 0.0 0.1 29.5 0.6 0.0 0.1 3.8 0.0 0.2 3.9 200.1 0.2 0.0 0.0 1.9 1.3 0.1 0.0 14.0 7.4 0.4 0.2 0.0 0.1 3.4 0.6 10.2 0.2 0.3 0.1 0.2 1.9 225.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.2 0.0 0.0 4.1 12.1 17.3 63.6 3.2 25.1 16.9 15.2 15.1 10.9 17.2 27.8 1.2 0.0 0.0 0.0 1.1 3.6 33.1 52.4 36.5 4.8 2.4 10.9 0.7 0.0 3.8 0.0 4.2 0.5 4.0 0.0 0.0 0.1 0.7 0.2 0.6 1.3 0.0 0.0 0.1 0.0 0.5 7.3 0.5 0.2 0.0 0.0 1.8 0.2 0.1 0.0 0.0 0.0 89.5 0.0 3.1 2.9 96.0 0.7 16.0 0.0 0.0 151.7 0.0 0.0 6.5 0.0 0.0 27.8 1.0 3.7 0.0 0.1 1.7 7.0 32.9 1.7 12.9 0.4 0.9 1.8 1.7 0.1 2.3 0.4 0.0 2.9 NIBAN1 "C1orf24, FAM129A, GIG39, NIBAN" ENSG00000135842 "Niban apoptosis regulator 1" Q9BZQ8 1 184790724-184974508 "Cancer-related genes, Predicted intracellular proteins" "Stress response, Translation regulation" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 164.1" "Cell type enriched" "Detected in some" 13 "Cardiomyocytes: 692.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 72.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 72.1" "Cell line enhanced" "Detected in many" "HDLM-2: 83.8;Karpas-707: 85.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA028172, HPA028231, HPA028657" Approved Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA028172: AB_10599602, HPA028231: AB_10601886, HPA028657: AB_10601680" "unprognostic (4.61e-3)" "unprognostic (3.45e-2)" "unprognostic (1.64e-3)" "unprognostic (9.46e-2)" "unprognostic (2.77e-1)" "unprognostic (3.87e-1)" "unprognostic (3.23e-2)" "unprognostic (1.30e-2)" "unprognostic (1.68e-1)" "unprognostic (6.32e-2)" "unprognostic (4.12e-1)" "unprognostic (1.32e-1)" "unprognostic (2.94e-3)" "unprognostic (9.01e-3)" "unprognostic (4.38e-2)" "unprognostic (3.73e-2)" "prognostic unfavorable (4.52e-4)" 18.2 7.8 1.4 38.9 1.6 8.8 24.0 1.5 1.9 14.8 3.1 104.7 8.5 24.2 6.2 61.2 22.1 27.7 164.1 1.5 2.0 3.3 2.7 18.1 11.3 3.9 2.4 4.9 85.7 4.2 2.1 6.2 3.1 59.6 15.9 0.8 100.6 43.1 60.9 8.8 18.5 41.0 2.8 12.3 58.9 1.9 2.2 12.2 15.3 41.2 17.3 105.8 14.6 3.2 42.0 0.5 0.2 0.1 28.0 42.2 1.6 21.1 42.9 17.7 22.3 0.0 17.3 0.0 13.6 54.2 4.6 46.0 2.4 1.5 28.4 83.8 3.2 17.5 8.2 0.0 65.2 57.2 19.1 39.1 65.3 52.1 62.4 12.6 0.1 6.3 4.2 85.5 0.5 0.2 1.9 10.0 11.1 0.0 4.3 13.3 9.9 0.8 24.5 0.8 2.3 2.1 0.4 0.1 29.9 7.0 9.0 17.9 3.3 35.0 0.1 6.3 43.5 71.1 30.2 8.7 68.8 23.4 35.3 20.4 3.6 10.9 5.1 2.1 4.4 1.0 4.7 5.0 5.2 0.3 0.4 1.8 72.1 5.7 0.8 0.5 11.9 2.2 1.4 1.6 1.5 1.9 1.5 2.0 3.9 2.4 3.1 2.8 2.2 3.2 20.1 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 692.7 0.0 0.0 0.0 0.0 0.4 52.8 0.0 0.0 0.0 0.0 0.0 0.0 5.3 0.0 0.0 0.0 0.0 1.2 24.7 0.0 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 43.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.0 0.0 0.0 0.0 0.0 0.4 27.4 0.0 0.0 0.0 NKX2-8 "Nkx2-9, NKX2.8, NKX2H" ENSG00000136327 "NK2 homeobox 8" O15522 14 36580004-36582614 "Plasma proteins, Predicted intracellular proteins, Transcription factors" "Developmental protein, DNA-binding" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 4.4;esophagus: 2.6;testis: 7.9" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 2.3;Basal squamous epithelial cells: 6.8;Late spermatids: 2.1;Oligodendrocytes: 2.6;Prostatic glandular cells: 2.1;Squamous epithelial cells: 3.4" "Cancer enhanced" "Detected in many" "thyroid cancer: 2.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.6;PC-3: 2.0" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA062879 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 61: Squamous epithelial cells - Keratinization" Nucleoplasm "Plasma membrane" "HPA062879: AB_2684892" "unprognostic (6.03e-2)" "unprognostic (1.75e-1)" "unprognostic (1.37e-3)" "unprognostic (2.27e-1)" "unprognostic (3.45e-4)" "unprognostic (2.36e-1)" "unprognostic (8.34e-2)" "unprognostic (7.80e-2)" "unprognostic (3.66e-1)" "unprognostic (3.11e-1)" "unprognostic (8.39e-3)" "unprognostic (4.60e-2)" "unprognostic (2.70e-1)" "unprognostic (6.13e-2)" 0.0 0.0 0.4 0.0 1.1 0.0 0.0 1.2 0.5 0.1 0.2 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.2 2.1 0.0 0.0 0.3 0.0 2.3 1.3 0.0 0.0 0.1 1.1 0.0 2.4 0.2 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 2.0 0.0 0.0 7.9 2.1 0.0 1.4 0.0 0.0 0.0 0.0 4.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.2 3.6 0.0 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.8 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.1 1.2 0.5 0.2 2.1 2.3 1.3 2.4 2.0 2.1 4.4 0.0 0.0 0.0 0.0 0.0 0.5 2.3 0.9 6.8 0.0 1.0 1.1 0.5 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.0 0.0 2.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 2.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.2 3.4 0.4 0.0 0.0 0.0 0.0 0.4 NLGN1 KIAA1070 ENSG00000169760 "Neuroligin 1" Q8N2Q7 3 173396284-174286644 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Biological rhythms, Cell adhesion" "Autism, Autism spectrum disorder, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 31.0;retina: 13.8" "Group enriched" "Detected in many" 31 "Excitatory neurons: 1484.7;Inhibitory neurons: 1700.0;Oligodendrocyte precursor cells: 4004.1;Oligodendrocytes: 1261.9" "Group enriched" "Detected in some" 9 "glioma: 3.8;melanoma: 2.2;renal cancer: 3.0" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 25.9;HUVEC TERT2: 24.9;RH-30: 26.2;WM-115: 27.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006572, HPA006680, CAB033261" Enhanced Uncertain "Nuclear bodies,Plasma membrane" "Intracellular and membrane" NA NA 82000 "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 17: WM-115 - Nervous system development" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Nuclear bodies" "CAB033261: AB_2151659, HPA006572: , HPA006680: AB_1854400" "unprognostic (2.81e-1)" "unprognostic (9.86e-2)" "unprognostic (3.08e-5)" "unprognostic (7.52e-5)" "unprognostic (1.03e-1)" "unprognostic (2.31e-1)" "unprognostic (6.67e-2)" "unprognostic (6.65e-2)" "unprognostic (1.78e-1)" "unprognostic (8.07e-2)" "unprognostic (3.21e-3)" "unprognostic (1.86e-2)" "unprognostic (1.97e-1)" "unprognostic (4.08e-2)" "unprognostic (8.81e-2)" "unprognostic (2.41e-3)" "unprognostic (5.37e-2)" 2.0 1.0 12.6 0.5 10.8 0.0 0.7 31.0 12.1 3.1 0.0 2.0 0.2 2.1 2.5 2.5 3.0 1.6 3.2 12.5 15.2 2.9 0.0 0.4 0.2 5.3 5.4 1.3 0.8 0.7 1.8 0.5 4.0 2.2 0.9 13.8 0.3 3.0 0.2 0.3 0.6 2.7 4.4 0.0 0.8 7.0 20.5 0.2 0.9 1.0 0.1 2.9 1.3 7.2 0.1 0.0 6.1 0.0 11.8 12.4 0.0 5.2 12.8 0.6 0.8 0.0 0.5 0.0 0.2 25.9 4.7 0.0 3.7 0.0 1.3 0.0 6.0 1.7 0.1 0.0 0.0 0.0 0.0 9.7 0.1 0.0 0.0 10.0 24.9 0.0 0.0 1.7 0.1 0.0 0.0 0.0 7.2 0.0 1.7 0.0 26.2 6.4 4.7 0.1 2.5 1.7 0.0 0.0 12.3 1.1 0.6 0.0 3.1 13.5 1.3 9.9 11.6 11.7 0.0 0.0 4.6 0.0 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.6 10.8 31.0 12.1 12.5 15.2 5.3 5.4 4.0 4.4 20.5 7.2 0.3 0.0 0.5 66.6 0.0 0.8 0.4 0.0 0.6 14.3 0.1 0.0 4.4 0.0 0.0 3.7 4.2 0.3 0.0 0.0 0.0 0.3 55.9 0.6 12.4 0.8 0.0 0.0 1484.7 0.0 0.2 8.2 0.0 0.3 0.0 0.3 0.0 0.0 0.1 0.0 1700.0 0.0 0.0 0.0 0.3 12.5 25.7 0.4 14.2 60.9 0.0 24.9 0.0 4004.1 1261.9 0.1 0.0 14.3 0.0 2.6 0.0 8.5 0.0 10.3 6.6 2.9 2.1 0.4 1.6 0.1 0.9 0.1 0.1 1.6 0.0 0.3 NMBR "BB1, BB1R" ENSG00000135577 "Neuromedin B receptor" P28336 6 142058330-142088799 "G-protein coupled receptors, Plasma proteins, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.5;testis: 1.4" "Cell type enhanced" "Detected in some" "Astrocytes: 3.3;Early spermatids: 7.0;Excitatory neurons: 2.3;Inhibitory neurons: 4.5;Late spermatids: 2.1;Oligodendrocyte precursor cells: 2.0;Oligodendrocytes: 2.5;Spermatocytes: 3.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA026665 Supported "Plasma membrane,Cytosol" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA026665: AB_1854527" "unprognostic (6.24e-2)" "unprognostic (3.05e-1)" "unprognostic (2.77e-2)" "unprognostic (7.88e-2)" "unprognostic (3.54e-2)" "unprognostic (8.21e-2)" "unprognostic (3.63e-2)" "unprognostic (1.54e-1)" "unprognostic (3.95e-1)" "unprognostic (7.94e-3)" "unprognostic (3.44e-1)" "unprognostic (2.11e-1)" "unprognostic (8.45e-2)" 0.0 0.0 0.7 0.0 1.0 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.8 0.0 0.0 0.2 1.3 0.0 0.0 0.1 0.0 1.0 1.1 0.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 1.1 0.0 0.0 1.4 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.0 0.0 0.6 0.2 1.3 1.0 1.1 1.5 1.1 0.5 0.2 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 0.0 2.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 2.0 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NMT1 NMT ENSG00000136448 "N-myristoyltransferase 1" P30419 17 44957992-45109016 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Hepatocytes: 344.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA022949, HPA022963" Supported Supported "Plasma membrane,Cytosol" NA NA 94000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 2: Hepatocytes - Metabolism" Cytosol "Plasma membrane" "HPA022949: AB_1854534, HPA022963: AB_1854535" "unprognostic (1.40e-1)" "unprognostic (2.87e-1)" "unprognostic (1.30e-2)" "unprognostic (6.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.64e-1)" "prognostic unfavorable (4.94e-4)" "unprognostic (4.96e-3)" "unprognostic (3.86e-1)" "unprognostic (3.04e-2)" "unprognostic (2.19e-1)" "unprognostic (1.98e-1)" "unprognostic (3.77e-3)" "unprognostic (1.01e-2)" "unprognostic (4.89e-2)" "unprognostic (4.17e-3)" "unprognostic (9.45e-2)" 28.3 31.8 36.2 22.3 37.7 19.5 25.8 30.3 43.4 24.7 27.9 27.8 23.6 26.4 15.7 28.8 27.7 20.3 28.3 38.8 36.4 27.3 39.5 26.5 33.6 35.4 33.7 26.3 22.2 37.8 23.3 36.6 35.0 24.5 29.2 25.7 32.1 27.6 44.6 23.9 26.4 32.9 33.9 28.4 24.5 24.9 37.2 35.2 30.7 47.6 39.5 33.0 23.5 34.9 51.5 88.8 53.7 42.3 82.9 75.0 60.6 41.4 87.6 115.9 101.0 83.9 57.0 54.0 86.2 80.4 78.4 51.5 94.5 92.3 132.9 117.9 73.3 49.0 60.7 84.4 53.7 71.0 62.6 66.4 64.1 79.1 69.2 64.1 87.1 60.9 81.8 38.1 63.1 49.2 76.2 31.7 42.4 151.5 87.8 57.5 67.2 52.2 73.6 78.8 39.2 32.9 33.0 30.2 38.0 112.8 73.1 46.0 50.1 69.9 49.5 55.8 68.1 41.4 61.0 69.9 64.5 44.5 56.4 34.9 49.4 20.0 23.8 33.3 19.9 42.3 19.9 20.1 26.2 31.0 23.7 18.8 26.5 21.1 27.6 115.5 25.7 11.8 36.2 37.7 30.3 43.4 38.8 36.4 35.4 33.7 35.0 33.9 37.2 34.9 50.1 38.5 29.5 49.3 53.8 13.9 15.4 48.8 24.5 97.8 74.1 57.1 46.5 97.2 33.6 69.9 116.7 73.7 87.5 48.7 78.2 69.4 31.1 51.5 63.1 46.4 50.9 72.0 30.3 71.2 61.9 39.6 21.9 62.3 22.8 28.1 85.3 344.4 47.6 129.5 30.7 43.0 28.5 86.5 15.9 12.2 55.0 34.6 10.6 18.7 97.9 41.5 59.8 20.1 19.3 67.9 52.0 51.1 31.0 15.3 84.1 108.1 24.0 123.5 59.2 16.1 46.3 67.6 35.5 20.5 14.1 81.8 40.1 25.4 68.6 18.6 NOS1 "nNOS, NOS" ENSG00000089250 "Nitric oxide synthase 1" P29475 12 117208142-117452170 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Calmodulin-binding, Oxidoreductase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "brain: 23.0;skeletal muscle: 36.9;tongue: 57.2" "Cell type enhanced" "Detected in some" "Basal prostatic cells: 10.0;Hepatic stellate cells: 18.2;Inhibitory neurons: 32.1;Oligodendrocyte precursor cells: 48.2" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 4.6;RH-30: 9.4;RPTEC TERT1: 5.8;U-2 OS: 1.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002167, HPA058312, HPA069509" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 80: Striated muscle - Unknown function" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "CAB002167: AB_564073, HPA058312: AB_2683676, HPA069509: " "unprognostic (1.63e-1)" "unprognostic (3.14e-2)" "unprognostic (2.18e-2)" "unprognostic (6.64e-3)" "unprognostic (4.91e-2)" "unprognostic (2.74e-1)" "unprognostic (2.54e-1)" "unprognostic (9.12e-3)" "unprognostic (2.51e-1)" "unprognostic (1.10e-1)" "unprognostic (1.07e-1)" "unprognostic (7.56e-2)" "unprognostic (1.01e-1)" "unprognostic (3.73e-2)" "unprognostic (1.34e-1)" "unprognostic (5.97e-4)" "unprognostic (1.87e-1)" 0.1 0.1 12.7 0.4 12.4 0.2 0.1 5.7 7.0 0.3 0.0 2.2 0.1 0.1 0.2 0.8 0.3 0.0 0.0 4.0 16.2 1.3 0.0 0.8 0.1 12.1 11.0 0.0 1.4 0.0 0.9 0.0 12.2 0.9 0.4 0.3 3.4 0.1 36.9 1.9 0.4 0.3 2.3 0.0 0.2 0.5 23.0 0.0 0.1 57.2 0.1 0.0 0.7 3.3 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 4.6 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 9.4 0.0 5.8 0.0 0.2 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 12.7 12.4 5.7 7.0 4.0 16.2 12.1 11.0 12.2 2.3 23.0 3.3 0.0 0.0 0.0 1.3 0.0 3.8 10.0 2.4 4.0 0.0 0.0 0.0 1.9 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.9 0.0 3.0 5.1 0.4 3.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 8.4 0.0 0.0 18.2 0.0 0.0 0.0 32.1 0.2 0.0 0.3 0.7 0.6 0.3 0.2 1.8 1.9 0.0 0.0 0.0 48.2 5.7 0.0 0.0 0.0 0.0 4.2 0.0 0.0 0.0 0.0 0.0 1.9 0.5 0.1 1.8 0.1 0.6 0.0 0.2 0.0 0.0 1.0 NOTCH2 ENSG00000134250 "Notch receptor 2" Q04721 1 119911553-120100779 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Notch signaling pathway, Transcription, Transcription regulation" "Activator, Developmental protein, Receptor" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA048743 Approved Supported "Nucleoplasm,Plasma membrane" NA NA 160000000 "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 28: Placenta - Pregnancy" "Cluster 18: U-2197 - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Nucleoplasm, Plasma membrane" "HPA048743: AB_2680508" "unprognostic (1.33e-1)" "unprognostic (1.43e-2)" "unprognostic (2.66e-1)" "unprognostic (1.40e-3)" "unprognostic (7.98e-2)" "unprognostic (4.01e-2)" "unprognostic (1.22e-1)" "unprognostic (7.32e-2)" "unprognostic (1.18e-2)" "prognostic unfavorable (5.24e-4)" "prognostic unfavorable (9.48e-4)" "unprognostic (3.86e-2)" "unprognostic (6.12e-3)" "unprognostic (1.55e-2)" "unprognostic (2.65e-2)" "unprognostic (1.12e-2)" "unprognostic (7.35e-3)" 27.1 12.9 16.4 20.4 13.6 13.7 24.8 11.9 16.4 31.0 20.3 16.0 5.4 21.2 20.8 24.9 25.7 18.5 14.2 15.9 13.7 10.9 19.6 20.2 16.7 20.6 18.6 33.9 20.1 12.1 5.5 24.9 13.9 20.4 13.6 19.3 17.1 22.2 6.4 32.3 11.9 26.6 15.7 25.3 10.5 25.4 19.3 15.3 21.2 8.9 17.9 19.0 24.1 14.8 54.2 17.7 27.0 20.7 108.5 92.7 26.6 39.7 54.8 51.8 55.8 16.3 14.2 1.4 32.6 75.3 46.2 20.1 42.8 35.3 82.5 64.0 27.2 32.1 45.7 1.6 40.5 32.7 8.0 75.5 22.5 155.2 103.7 78.4 26.9 14.5 0.8 65.3 63.7 59.2 13.9 9.2 34.6 5.0 19.6 9.1 94.2 36.1 27.3 33.4 1.1 13.4 54.5 50.0 27.9 53.4 28.0 11.7 97.0 67.0 45.8 102.7 63.1 27.9 16.8 16.5 98.7 29.5 65.2 15.0 14.9 22.9 1.4 7.3 1.4 39.0 1.6 0.9 23.7 33.3 3.1 2.0 8.9 2.4 10.5 12.3 3.8 4.4 16.4 13.6 11.9 16.4 15.9 13.7 20.6 18.6 13.9 15.7 19.3 14.8 4.6 35.3 19.5 125.4 36.6 46.3 56.6 14.8 31.3 3.3 38.1 25.3 16.0 24.3 28.5 18.4 6.2 1.6 26.0 6.2 0.0 46.8 17.7 33.8 21.9 5.4 6.1 18.3 4.2 12.9 8.9 67.8 5.1 61.1 15.8 78.3 3.9 41.5 32.7 3.3 22.6 7.9 20.3 74.7 78.2 12.6 55.0 76.6 39.2 43.1 79.3 46.2 15.5 75.4 0.6 26.8 105.5 85.4 14.2 37.2 3.2 4.9 16.4 10.5 19.7 83.6 34.0 10.0 4.3 75.1 88.9 1.6 18.5 22.0 15.8 66.9 NOXRED1 "C14orf148, FLJ32809" ENSG00000165555 "NADP dependent oxidoreductase domain containing 1" Q6NXP6 14 77394021-77423517 "Predicted intracellular proteins" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "retina: 5.9;testis: 6.9" "Group enriched" "Detected in some" 25 "Early spermatids: 137.8;Late spermatids: 125.8" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Low region specificity" "Detected in all" "HPA055658, HPA060408" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 34: Spermatids - Unknown function" Vesicles "Plasma membrane" "HPA055658: AB_2682878, HPA060408: " "unprognostic (1.92e-2)" "unprognostic (4.83e-2)" "unprognostic (1.14e-1)" "unprognostic (1.55e-1)" "unprognostic (2.49e-2)" "unprognostic (9.87e-2)" "unprognostic (1.92e-2)" "unprognostic (1.36e-1)" "unprognostic (2.39e-2)" "unprognostic (2.61e-1)" "unprognostic (1.08e-3)" "unprognostic (1.24e-2)" "unprognostic (1.29e-2)" "unprognostic (2.60e-1)" "unprognostic (5.70e-2)" "unprognostic (1.70e-3)" "unprognostic (1.07e-3)" 0.2 0.6 0.5 0.1 0.6 0.2 0.5 0.2 0.5 0.2 1.7 0.5 0.5 0.5 0.5 0.3 0.5 0.6 0.1 0.5 0.6 0.5 0.3 0.3 0.6 0.8 1.0 0.3 0.4 0.2 0.7 0.3 0.7 0.3 0.5 5.9 0.2 0.4 0.1 1.1 0.3 0.4 0.9 0.5 0.2 6.9 0.5 0.5 0.9 0.0 0.4 0.2 0.2 0.7 0.3 0.7 0.3 0.4 0.1 0.7 0.5 0.3 0.5 0.3 0.2 0.4 0.3 0.7 0.1 0.6 0.1 0.2 0.1 0.1 0.4 0.3 0.2 0.4 0.0 0.7 0.2 0.1 0.6 0.4 0.9 0.3 0.5 0.4 0.2 0.8 0.1 0.5 0.1 0.8 0.2 0.2 0.0 0.2 0.6 0.2 0.1 0.0 0.3 0.1 0.7 0.5 0.4 0.1 0.1 0.7 0.7 0.4 0.9 0.2 0.2 0.4 0.1 0.7 0.7 0.4 0.3 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.6 0.2 0.5 0.5 0.6 0.8 1.0 0.7 0.9 0.5 0.7 0.2 0.0 0.0 5.2 0.2 0.0 0.0 0.0 0.0 0.4 0.2 0.3 0.1 0.0 0.1 0.0 4.2 0.0 0.0 0.3 0.0 0.0 137.8 0.6 0.1 0.2 1.8 0.0 4.1 0.0 0.1 0.0 0.0 0.1 0.0 0.3 0.0 0.3 0.1 0.0 3.0 0.0 0.0 0.3 0.2 125.8 0.9 0.3 0.0 0.0 0.0 0.4 0.0 3.0 4.4 0.1 0.0 1.2 0.1 0.1 0.3 0.1 0.2 1.5 0.0 0.0 0.1 4.1 2.2 0.0 0.0 0.0 0.0 0.2 0.1 0.1 NPFFR2 "GPR74, NPFF2, NPGPR" ENSG00000056291 "Neuropeptide FF receptor 2" Q9Y5X5 4 72031804-72148067 "G-protein coupled receptors, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 7.2;seminal vesicle: 3.2" "Cell type enhanced" "Detected in some" "Breast glandular cells: 22.1;Cytotrophoblasts: 6.6;Excitatory neurons: 14.5;Extravillous trophoblasts: 12.3;Muller glia cells: 4.9;Syncytiotrophoblasts: 9.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 8 "GAMG: 28.1;NTERA-2: 9.2;RPTEC TERT1: 11.9;SH-SY5Y: 14.0;U-2 OS: 13.7" "Region enriched" "Detected in some" 4 "olfactory bulb: 4.3" "Low region specificity" "Detected in all" HPA026825 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 63: T-cells - Adaptive immune response" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane" "Actin filaments" "HPA026825: AB_10603123" "unprognostic (1.28e-1)" "unprognostic (1.05e-2)" "unprognostic (1.53e-1)" "unprognostic (1.23e-1)" "unprognostic (6.07e-2)" "unprognostic (4.68e-2)" "unprognostic (5.77e-2)" "unprognostic (1.43e-2)" "unprognostic (1.34e-1)" "unprognostic (1.51e-1)" "unprognostic (2.40e-5)" "unprognostic (5.75e-2)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (1.48e-1)" 0.1 0.0 1.0 0.2 0.9 0.0 0.2 0.0 0.6 0.1 0.0 0.1 0.1 0.0 0.9 0.0 0.2 0.1 0.0 0.9 1.1 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 1.6 0.3 0.1 0.2 0.7 0.0 3.2 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.4 0.2 7.2 0.3 0.2 0.1 0.5 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 28.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.2 0.0 0.0 0.0 0.0 0.0 11.9 0.0 0.0 14.0 0.0 0.0 0.0 2.0 0.0 0.0 1.3 0.0 13.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 1.0 0.9 0.0 0.6 0.9 1.1 0.5 0.0 0.3 0.0 0.2 0.5 0.1 0.0 0.0 0.7 0.0 0.4 0.0 0.0 0.0 0.0 22.1 0.0 0.5 0.0 0.0 0.0 0.0 6.6 0.0 0.1 0.0 0.2 0.8 0.0 0.0 0.3 0.0 0.0 14.5 0.2 12.3 1.5 0.0 0.0 0.0 0.0 0.0 0.0 1.0 3.3 3.5 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 4.9 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 1.7 0.0 0.0 9.7 0.0 0.0 0.0 0.1 NPL "C1orf13, DHDPS1, NPL1" ENSG00000135838 "N-acetylneuraminate pyruvate lyase" Q9BXD5 1 182789293-182830384 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Carbohydrate metabolism" Lyase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "kidney: 52.3;placenta: 45.2" "Cell type enhanced" "Detected in many" "Astrocytes: 170.1;Cytotrophoblasts: 123.1;Hofbauer cells: 481.5;Kupffer cells: 148.8;Microglial cells: 125.5;Proximal tubular cells: 141.0;Syncytiotrophoblasts: 107.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 423.2" "Group enriched" "Detected in many" 34 "granulocytes: 423.2;monocytes: 128.4" "Cell line enhanced" "Detected in many" "HEL: 14.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028345, HPA075808" Enhanced Approved "Vesicles,Plasma membrane" NA NA 190000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 7: Kidney - Transmembrane transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 4: Macrophages - Innate immune response" Vesicles "Plasma membrane" "HPA028345: AB_10610145, HPA075808: " "unprognostic (2.43e-2)" "unprognostic (5.71e-3)" "unprognostic (1.72e-2)" "unprognostic (1.06e-1)" "unprognostic (1.57e-1)" "unprognostic (3.06e-1)" "prognostic unfavorable (8.05e-4)" "unprognostic (4.41e-2)" "unprognostic (6.54e-3)" "unprognostic (1.45e-1)" "unprognostic (1.49e-1)" "unprognostic (6.18e-2)" "prognostic unfavorable (6.63e-4)" "unprognostic (2.11e-1)" "unprognostic (2.93e-2)" "unprognostic (2.35e-2)" "unprognostic (7.44e-2)" 12.7 5.8 16.7 19.2 20.8 18.9 5.5 19.3 22.9 4.3 11.1 6.9 2.8 1.7 29.9 10.0 3.3 13.0 2.6 12.7 15.6 52.3 20.8 14.5 32.5 19.6 20.1 1.4 2.8 3.3 1.7 45.2 18.9 2.3 9.1 1.9 4.2 6.2 1.7 8.4 4.4 7.5 15.8 28.7 5.0 5.1 27.0 6.2 2.6 2.8 14.7 15.5 5.1 22.0 3.4 0.6 1.0 0.0 2.8 2.8 0.9 1.1 2.1 1.2 0.6 0.0 1.4 9.0 1.5 0.0 0.0 1.3 1.9 2.4 0.3 0.0 1.5 14.2 0.4 0.1 1.5 5.4 8.1 2.2 9.1 0.2 0.0 0.1 0.1 10.1 10.9 13.8 2.1 1.1 0.3 3.5 11.0 7.0 1.1 1.4 0.7 11.0 0.2 7.4 3.1 4.6 5.0 0.3 4.7 1.1 2.9 8.7 0.2 1.1 2.4 0.7 0.1 9.8 12.7 9.0 2.4 9.5 3.6 25.5 128.4 104.1 5.5 118.2 4.8 1.8 4.5 4.9 7.6 6.3 3.5 4.9 423.2 0.3 96.6 1.5 8.1 65.4 16.7 20.8 19.3 22.9 12.7 15.6 19.6 20.1 18.9 15.8 27.0 22.0 2.9 0.0 5.5 170.1 4.9 6.1 4.0 8.6 1.8 7.6 1.5 4.4 2.9 2.8 4.8 7.3 2.1 123.1 2.2 2.3 19.6 1.2 19.1 0.4 0.6 3.5 1.8 45.5 7.5 2.4 6.1 2.5 3.1 0.2 5.7 0.5 72.8 3.9 481.5 6.7 13.5 1.4 6.1 148.8 11.5 27.0 0.9 91.7 10.6 125.5 40.1 2.8 5.2 22.1 21.0 1.3 0.3 0.4 0.7 1.6 0.9 141.0 1.7 2.8 0.0 1.7 1.7 16.5 8.9 16.5 7.1 107.4 3.1 3.4 1.6 4.3 NRSN1 "p24, VMP" ENSG00000152954 "Neurensin 1" Q8IZ57 6 24126186-24154900 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 22 "brain: 542.9;choroid plexus: 474.7" "Cell type enhanced" "Detected in some" "Excitatory neurons: 139.1;Horizontal cells: 121.1;Inhibitory neurons: 111.9;Oligodendrocyte precursor cells: 69.9" "Cancer enriched" "Detected in single" 17 "glioma: 3.1" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 11 "SCLC-21H: 11.2;SH-SY5Y: 9.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA019681, HPA061006" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA019681: , HPA061006: AB_2684413" "unprognostic (1.22e-1)" "unprognostic (4.26e-2)" "unprognostic (8.00e-3)" "unprognostic (8.01e-3)" "unprognostic (1.70e-1)" "unprognostic (4.53e-3)" "unprognostic (7.29e-2)" "unprognostic (1.36e-3)" "unprognostic (2.40e-3)" "unprognostic (1.45e-1)" "unprognostic (1.57e-1)" 0.0 4.9 276.8 0.4 315.2 0.2 0.0 108.9 281.1 0.1 474.7 1.2 0.4 0.2 0.0 0.1 0.0 0.2 0.0 138.2 466.8 0.1 0.0 0.0 0.1 263.2 332.8 0.0 1.2 0.0 23.5 0.0 468.0 0.0 0.4 22.6 0.1 0.0 0.7 0.1 0.3 0.3 194.7 0.1 0.4 0.3 459.9 0.0 0.1 0.0 0.1 0.0 0.1 542.9 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.5 0.4 0.1 0.1 0.1 0.1 0.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 11.2 9.2 0.0 0.0 0.2 0.1 0.0 0.9 0.1 0.1 0.1 0.0 0.0 0.3 0.5 0.2 0.3 0.0 0.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 276.8 315.2 108.9 281.1 138.2 466.8 263.2 332.8 468.0 194.7 459.9 542.9 0.0 0.0 0.0 17.3 0.0 0.0 0.0 0.0 0.0 27.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.8 0.0 0.1 0.0 0.0 139.1 0.0 0.0 0.0 0.0 1.2 0.0 0.1 0.0 0.0 0.0 121.1 111.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 12.2 0.0 23.7 0.0 69.9 5.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.9 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 NSD1 "ARA267, FLJ22263, KMT3B, STO" ENSG00000165671 "Nuclear receptor binding SET domain protein 1" Q96L73 5 177133025-177300213 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Transcription, Transcription regulation" "Activator, Chromatin regulator, Methyltransferase, Repressor, Transferase" "Cancer-related genes, Disease variant, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA048431, HPA070333, HPA073705" Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 44: HDLM-2 - Immune response" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA048431: AB_2680388, HPA070333: AB_2686255, HPA073705: AB_2732239" "unprognostic (3.48e-2)" "unprognostic (7.46e-2)" "unprognostic (7.14e-3)" "unprognostic (2.64e-3)" "unprognostic (1.38e-1)" "unprognostic (9.67e-2)" "unprognostic (2.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.68e-3)" "unprognostic (8.04e-2)" "unprognostic (1.48e-1)" "unprognostic (2.09e-1)" "unprognostic (7.77e-3)" "unprognostic (3.53e-2)" "unprognostic (1.01e-1)" "unprognostic (7.51e-2)" "unprognostic (7.32e-2)" 8.7 7.2 8.9 12.0 13.4 21.2 10.9 26.2 10.4 11.1 9.8 10.1 8.4 11.5 10.3 11.4 10.1 8.0 9.1 7.7 10.0 10.6 6.6 9.2 13.7 9.7 10.8 12.3 11.3 12.8 9.0 10.7 12.2 9.3 10.8 11.9 10.4 9.6 13.6 12.0 9.4 12.0 6.6 11.3 8.9 23.2 12.0 20.2 15.5 11.5 14.7 9.3 7.9 17.5 20.5 25.9 26.0 22.8 12.5 16.1 0.9 18.2 17.9 24.6 22.8 5.7 16.6 41.7 19.9 24.8 22.7 17.0 41.9 40.0 29.7 72.9 25.9 18.6 29.5 0.2 20.7 40.4 21.2 15.2 23.6 29.4 27.3 17.5 36.4 26.0 25.9 14.3 25.2 42.3 28.3 13.1 28.5 13.7 22.5 31.0 3.4 12.9 15.9 24.4 31.6 21.9 46.7 20.1 13.8 24.1 20.2 33.0 27.4 17.1 25.0 11.0 22.6 16.7 15.7 29.5 9.9 19.3 18.7 14.7 9.0 10.5 7.2 6.1 6.0 8.5 6.1 5.0 7.2 10.3 7.5 6.0 18.6 11.3 12.2 9.4 6.4 3.4 8.9 13.4 26.2 10.4 7.7 10.0 9.7 10.8 12.2 6.6 12.0 17.5 37.4 22.4 31.4 84.9 71.7 17.0 32.8 27.2 34.1 94.4 29.8 25.7 44.5 34.3 35.0 55.2 150.1 43.6 66.1 19.7 17.6 27.8 31.9 27.1 65.7 36.4 41.9 48.3 107.0 21.2 23.7 32.7 41.8 41.9 41.7 64.0 33.5 19.9 27.7 89.2 110.3 25.6 12.2 36.8 25.7 50.3 51.0 47.1 16.0 115.2 75.0 29.2 95.8 140.8 157.5 23.7 31.0 33.1 55.8 29.4 33.6 19.2 17.3 112.3 52.6 42.9 36.1 83.7 62.1 41.8 20.6 35.4 62.0 55.9 28.2 30.0 NUDT16L1 "SDOS, TIRR" ENSG00000168101 "Nudix hydrolase 16 like 1" Q9BRJ7 16 4693694-4695859 "Predicted intracellular proteins" RNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044186, HPA063605" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 5: Granulocytes - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA044186: AB_10968571, HPA063605: AB_2685058" "unprognostic (1.35e-2)" "unprognostic (1.70e-1)" "unprognostic (6.65e-2)" "unprognostic (2.17e-2)" "unprognostic (1.02e-1)" "unprognostic (2.34e-2)" "unprognostic (3.14e-1)" "prognostic favorable (2.79e-4)" "unprognostic (2.51e-1)" "unprognostic (1.89e-1)" "unprognostic (6.12e-3)" "unprognostic (6.81e-2)" "prognostic favorable (1.02e-6)" "unprognostic (2.78e-1)" "unprognostic (1.47e-1)" "unprognostic (4.08e-2)" "unprognostic (6.81e-3)" 19.7 46.4 43.1 12.0 44.8 22.2 21.5 43.6 52.5 23.1 45.6 28.5 21.7 21.4 15.3 28.9 23.4 8.4 58.2 44.1 42.0 43.4 64.1 17.2 17.9 45.3 43.2 22.7 24.6 20.4 39.9 8.0 41.9 34.8 11.9 14.5 26.6 14.7 25.0 25.2 29.2 8.5 43.3 33.7 30.1 22.8 44.3 18.2 30.8 16.9 13.1 22.7 21.8 45.7 14.7 23.8 21.2 28.7 15.7 12.1 19.4 17.2 12.9 20.4 12.8 26.9 11.6 15.2 24.4 20.7 10.3 16.8 23.1 23.4 9.5 22.6 38.9 16.8 21.1 32.8 17.0 24.4 19.2 18.7 21.3 17.2 10.7 13.9 15.1 22.6 31.2 18.5 20.1 57.3 36.8 36.0 33.6 24.4 27.0 50.9 22.4 24.2 24.8 18.0 41.8 31.5 25.1 25.9 11.7 16.5 38.4 56.4 20.0 16.7 25.3 39.8 15.9 32.1 20.5 26.1 10.4 32.3 34.8 56.6 54.3 96.2 52.6 48.2 63.1 60.7 63.4 62.8 50.2 65.3 74.0 63.5 68.2 63.9 53.5 83.6 78.3 98.1 43.1 44.8 43.6 52.5 44.1 42.0 45.3 43.2 41.9 43.3 44.3 45.7 23.3 16.0 22.4 14.4 32.6 14.0 19.7 37.4 27.9 52.1 36.0 36.2 52.6 24.3 28.0 42.3 10.4 53.8 43.6 47.7 109.5 28.7 5.2 28.7 33.6 21.4 43.1 23.1 10.2 30.9 31.8 24.0 30.5 29.0 27.9 31.7 17.9 41.8 40.9 47.1 11.8 51.7 89.5 18.3 18.7 8.7 31.4 20.8 30.2 3.7 43.3 83.5 34.0 9.5 15.0 30.0 48.5 50.0 33.0 17.9 77.8 98.2 20.1 58.3 46.0 14.2 22.8 14.8 34.7 24.9 16.6 49.1 43.6 58.0 51.4 17.6 NUS1 "C6orf68, MGC7199, NgBR, TANGO14" ENSG00000153989 "NUS1 dehydrodolichyl diphosphate synthase subunit" Q96E22 6 117675469-117710727 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted membrane proteins" "Angiogenesis, Differentiation, Lipid metabolism" "Developmental protein, Receptor, Transferase" "Congenital disorder of glycosylation, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027504 Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 29: Non-specific - Vesicular transport" "Cluster 1: K-562 - Erythropoiesis" "Cluster 55: Plasma cells - Humoral immune response" Vesicles "Plasma membrane" "HPA027504: AB_10603124" "unprognostic (1.21e-2)" "prognostic unfavorable (6.99e-4)" "unprognostic (1.09e-2)" "unprognostic (2.31e-1)" "unprognostic (1.21e-1)" "unprognostic (8.26e-3)" "unprognostic (1.42e-3)" "unprognostic (2.42e-2)" "unprognostic (8.62e-2)" "unprognostic (2.99e-1)" "unprognostic (2.62e-1)" "unprognostic (8.35e-2)" "unprognostic (1.00e-1)" "unprognostic (2.27e-1)" "unprognostic (3.22e-2)" "unprognostic (1.56e-1)" "unprognostic (7.97e-2)" 17.8 20.0 12.1 22.2 13.0 19.4 22.2 11.4 15.5 60.3 16.1 19.8 16.5 20.6 28.4 15.7 18.4 16.1 11.7 12.9 13.8 28.4 31.6 18.2 21.4 10.8 12.5 16.5 20.4 29.8 11.9 21.6 11.9 20.6 20.3 12.5 30.5 17.6 10.0 11.1 17.6 18.7 11.7 17.8 24.2 12.6 13.5 18.5 35.4 12.6 20.6 23.5 11.7 12.4 27.1 19.5 41.3 46.4 40.7 52.9 101.0 48.3 50.1 39.5 45.1 44.6 29.5 63.4 51.1 44.7 50.0 24.0 62.1 47.2 73.0 47.9 57.0 72.8 31.5 80.2 62.6 92.8 41.2 46.6 52.5 43.3 87.7 40.3 41.3 46.5 88.4 54.9 59.7 30.5 43.9 58.8 48.0 36.9 35.3 41.7 29.7 45.7 79.0 26.6 48.7 38.5 29.1 37.4 36.9 45.6 23.8 95.9 36.4 24.3 30.1 39.2 70.5 75.6 60.8 66.8 57.6 70.0 49.7 1.9 1.3 0.8 1.3 1.4 1.9 1.1 1.6 1.8 1.5 1.0 1.3 1.7 0.1 1.9 2.5 3.8 1.7 1.0 12.1 13.0 11.4 15.5 12.9 13.8 10.8 12.5 11.9 11.7 13.5 12.4 18.7 0.0 22.3 30.3 28.5 60.5 41.9 32.6 19.4 15.3 26.6 13.7 6.3 15.7 24.0 25.8 10.4 26.8 38.1 26.4 27.4 23.4 16.0 15.7 28.9 24.3 13.1 19.1 33.4 30.2 63.6 22.8 38.2 21.4 31.1 15.8 28.2 39.7 35.3 15.2 37.1 29.3 20.3 37.0 42.2 14.0 18.0 30.2 32.0 20.6 28.4 8.3 24.7 35.7 36.5 37.4 22.7 20.3 57.5 73.1 18.6 33.6 23.1 9.6 6.6 21.3 25.9 24.9 25.4 25.7 56.1 57.9 26.2 14.5 26.1 77.5 OBSCN "ARHGEF30, KIAA1556, KIAA1639, UNC89" ENSG00000154358 "Obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF" Q5VST9 1 228208044-228378876 "Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Calmodulin-binding, Developmental protein, Kinase, Muscle protein, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "skeletal muscle: 481.3" "Cell type enriched" "Detected in many" 6 "Cardiomyocytes: 155.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 10.5" "Low region specificity" "Detected in single" "Low region specificity" "Detected in many" "HPA021186, HPA065801" Enhanced Approved "Plasma membrane,Cytosol" NA NA 4500000 "Cluster 7: Monocytes - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA021186: AB_1854761, HPA065801: " "unprognostic (8.47e-3)" "unprognostic (1.56e-1)" "unprognostic (9.99e-2)" "prognostic unfavorable (1.64e-4)" "unprognostic (5.30e-3)" "unprognostic (6.36e-2)" "unprognostic (4.54e-3)" "unprognostic (1.82e-1)" "unprognostic (8.81e-2)" "unprognostic (1.93e-2)" "unprognostic (3.38e-1)" "unprognostic (1.45e-1)" "unprognostic (1.57e-3)" "unprognostic (1.34e-1)" "unprognostic (1.77e-1)" "unprognostic (3.53e-1)" "unprognostic (1.16e-2)" 3.5 2.5 2.4 1.4 18.4 1.6 3.7 10.4 4.4 8.1 18.1 5.2 0.7 3.7 1.8 4.6 5.1 1.1 78.5 0.9 2.7 6.6 1.3 8.9 2.1 4.3 2.7 8.6 5.4 1.1 13.6 0.9 2.4 9.9 0.5 0.8 9.4 1.7 481.3 4.7 5.4 0.5 1.0 9.3 5.2 1.9 6.3 4.9 7.5 112.8 1.3 3.2 7.4 0.1 1.7 2.8 3.6 3.7 0.2 0.2 4.6 1.6 0.7 1.7 1.4 2.1 1.3 3.2 5.4 0.7 0.7 2.1 1.3 2.2 0.3 2.0 3.4 1.7 10.5 0.1 1.2 2.4 2.2 1.4 0.6 0.4 0.5 5.1 0.5 7.0 3.2 0.0 0.3 1.8 3.3 3.5 4.9 0.6 2.1 4.4 0.0 1.9 1.8 1.4 1.7 6.3 0.6 3.9 1.0 0.8 3.4 4.0 1.0 0.0 5.1 0.3 0.5 2.5 0.5 4.7 0.0 0.8 2.1 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.2 0.1 0.3 0.1 0.0 0.0 0.0 0.1 0.1 0.1 2.4 18.4 10.4 4.4 0.9 2.7 4.3 2.7 2.4 1.0 6.3 0.1 1.5 0.0 5.5 1.6 2.4 2.2 6.6 7.7 23.9 4.2 7.3 11.9 155.8 4.3 4.5 5.5 10.4 0.1 1.9 0.7 11.7 3.6 4.9 3.9 3.7 3.1 0.0 3.0 3.9 0.5 0.5 5.7 3.1 11.3 7.0 1.8 1.4 0.5 0.1 0.0 5.3 2.7 4.1 0.3 1.0 4.5 3.1 1.1 1.8 5.6 0.5 7.9 4.1 1.5 1.7 0.8 1.1 4.5 1.5 3.8 0.6 4.1 1.3 3.2 0.0 22.9 6.1 1.0 4.1 9.4 1.7 1.2 5.4 6.2 1.2 3.6 OCA2 "BEY, BEY1, BEY2, D15S12, EYCL, EYCL2, EYCL3, P" ENSG00000104044 "OCA2 melanosomal transmembrane protein" Q04671 15 27754875-28099315 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Albinism, Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "choroid plexus: 28.1" "Cell type enhanced" "Detected in some" "Excitatory neurons: 30.9;Inhibitory neurons: 40.8;Melanocytes: 42.7;Peritubular cells: 14.7" "Cancer enriched" "Detected in many" 17 "melanoma: 19.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SK-MEL-30: 24.6" "Low region specificity" "Detected in some" HPA036402 Approved "Plasma membrane,Cytosol" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA036402: " "unprognostic (6.07e-3)" "unprognostic (1.97e-2)" "unprognostic (3.25e-1)" "unprognostic (2.82e-2)" "unprognostic (4.60e-4)" "unprognostic (7.11e-2)" "unprognostic (1.10e-1)" "unprognostic (4.12e-2)" "unprognostic (3.47e-2)" "unprognostic (4.95e-2)" "unprognostic (1.96e-2)" "unprognostic (1.60e-2)" "unprognostic (2.20e-6)" "unprognostic (2.61e-1)" "unprognostic (4.21e-1)" "unprognostic (3.28e-2)" "unprognostic (2.28e-2)" 0.3 0.0 1.8 0.1 1.8 0.0 0.3 0.1 1.8 1.2 28.1 0.1 0.0 0.2 0.3 2.2 1.1 0.0 0.3 1.4 1.8 0.3 0.1 0.6 1.8 0.5 0.9 0.3 0.0 0.0 0.8 1.5 0.6 0.6 0.0 0.0 0.8 1.0 0.2 6.4 0.2 0.0 0.0 1.1 0.1 1.9 2.4 0.4 4.2 0.0 0.7 0.2 2.4 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 1.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 2.2 0.0 0.1 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.5 0.0 0.0 0.5 0.0 0.0 0.1 5.6 0.0 0.0 24.6 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.8 1.8 0.1 1.8 1.4 1.8 0.5 0.9 0.6 0.0 2.4 1.0 0.0 0.0 0.0 0.7 0.0 2.0 0.1 0.1 0.6 0.0 0.0 0.4 0.4 0.0 1.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 4.4 5.6 0.2 0.1 0.0 0.0 30.9 0.0 0.1 1.4 0.0 2.8 0.0 2.3 0.0 0.0 0.1 0.0 40.8 0.1 0.0 0.0 0.9 3.0 9.3 0.1 42.7 0.0 0.0 0.0 0.0 2.5 0.8 0.0 1.2 14.7 0.0 0.0 0.0 0.1 2.0 0.0 0.0 1.0 0.8 4.2 4.9 6.1 0.9 0.1 0.1 0.4 0.1 0.2 OCLN PPP1R115 ENSG00000197822 Occludin Q16625 5 69492292-69558104 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "thyroid gland: 31.4" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 109.0;Glandular and luminal cells: 119.7;Urothelial cells: 224.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 2.7" "Cell line enhanced" "Detected in many" "A-431: 23.3;CAPAN-2: 39.8;HaCaT: 33.4;RPTEC TERT1: 25.7;SK-BR-3: 27.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005933, CAB013075, CAB068212, CAB068213, CAB068214" Enhanced Supported "Plasma membrane,Cell Junctions" "Intracellular and membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 29: Non-specific - Vesicular transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cell Junctions" "CAB013075: AB_2533101, CAB068212: AB_2665711, CAB068213: AB_2665712, CAB068214: AB_2665713, HPA005933: AB_1079520" "unprognostic (2.28e-1)" "unprognostic (1.88e-1)" "unprognostic (2.50e-2)" "unprognostic (9.94e-2)" "unprognostic (3.65e-1)" "unprognostic (1.39e-1)" "unprognostic (2.24e-1)" "unprognostic (1.08e-2)" "unprognostic (8.25e-2)" "unprognostic (8.20e-2)" "unprognostic (2.58e-2)" "unprognostic (3.48e-1)" "prognostic favorable (6.59e-11)" "unprognostic (2.83e-1)" "unprognostic (4.01e-1)" "unprognostic (1.33e-1)" "unprognostic (3.35e-1)" 1.2 0.7 6.2 1.6 6.5 1.8 7.8 7.2 6.7 6.8 22.2 11.0 10.3 2.1 4.0 11.6 7.5 8.5 1.5 5.9 5.4 11.0 18.8 15.1 0.6 9.3 7.7 2.3 20.2 8.3 3.4 3.9 8.3 3.5 11.2 2.3 6.7 4.6 0.6 11.3 10.0 0.6 5.4 2.1 15.2 2.4 6.5 0.9 31.4 0.6 2.8 5.0 7.9 7.4 23.3 4.5 0.6 0.9 0.6 0.9 15.1 0.3 1.6 2.5 3.3 20.7 39.8 0.5 5.9 1.1 8.3 33.4 7.2 4.3 7.8 0.3 12.2 2.4 1.1 9.8 0.3 1.2 2.5 0.1 6.4 4.1 1.0 1.6 1.4 3.1 0.1 0.4 0.1 22.4 1.5 1.2 3.1 8.0 2.1 0.2 6.0 1.1 25.7 22.2 2.7 2.8 0.3 27.2 0.9 5.0 14.7 4.0 1.2 0.4 7.7 1.8 2.7 0.5 0.4 0.3 0.3 0.3 0.6 1.0 0.2 0.5 0.2 0.1 0.2 0.3 0.2 0.1 0.1 0.4 0.2 0.2 2.7 0.5 0.1 0.4 0.1 0.1 6.2 6.5 7.2 6.7 5.9 5.4 9.3 7.7 8.3 5.4 6.5 7.4 4.8 109.0 67.3 1.6 3.2 3.7 60.8 7.6 1.8 5.7 49.7 16.9 1.4 64.3 51.0 25.8 14.6 30.3 3.6 94.1 9.8 65.6 1.9 78.5 12.1 10.7 26.3 2.5 1.3 61.6 2.5 5.8 46.4 119.7 2.5 6.5 18.2 48.3 3.0 6.7 1.1 45.1 16.2 12.9 1.2 1.6 3.1 2.4 1.8 16.9 3.9 2.8 1.0 0.5 1.5 64.6 61.8 1.5 1.1 101.5 42.3 10.5 63.0 6.3 13.1 3.3 4.4 4.7 8.2 29.5 15.5 16.4 4.3 0.7 47.9 224.0 OCM OCM1 ENSG00000122543 Oncomodulin P0CE72 7 5879827-5886363 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.2" "Cell type enhanced" "Detected in some" "Astrocytes: 2.6;Early spermatids: 2.3;Excitatory neurons: 8.6;Inhibitory neurons: 7.0;Late spermatids: 2.4;Microglial cells: 4.7;Oligodendrocytes: 2.1" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "T-reg: 2.7" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 65: Brain - Ion transport" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA046422: AB_2679659, HPA052483: " "unprognostic (1.79e-2)" "unprognostic (2.55e-2)" "unprognostic (3.97e-1)" "unprognostic (1.50e-1)" "unprognostic (5.39e-2)" "unprognostic (1.31e-2)" "unprognostic (2.30e-2)" "unprognostic (7.62e-3)" "unprognostic (2.47e-1)" "unprognostic (1.52e-1)" "unprognostic (1.92e-3)" "unprognostic (6.13e-2)" "unprognostic (2.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.02e-1)" "unprognostic (3.23e-1)" "unprognostic (3.90e-4)" 0.2 0.2 2.9 0.3 2.1 0.7 0.5 2.3 3.2 0.4 1.6 0.2 0.0 0.1 0.9 0.2 0.3 0.2 0.1 2.1 2.4 0.3 0.3 0.2 2.1 1.9 2.0 0.3 0.2 0.0 0.3 0.0 2.0 0.3 0.2 0.6 0.3 0.3 0.1 0.7 0.7 0.1 1.8 1.2 0.2 2.1 2.4 0.8 0.3 0.0 0.8 0.1 0.3 2.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.1 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.3 0.8 0.4 0.2 0.1 0.4 1.1 0.3 0.0 1.4 1.5 0.4 0.6 0.0 0.2 0.0 2.7 0.4 2.9 2.1 2.3 3.2 2.1 2.4 1.9 2.0 2.0 1.8 2.4 2.2 0.1 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.0 0.5 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 2.3 0.0 0.0 0.1 0.0 0.0 8.6 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 7.0 0.0 0.0 0.6 0.0 2.4 0.0 0.1 0.0 4.7 0.3 0.5 1.0 1.5 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 1.0 0.0 0.0 0.0 0.5 0.0 0.0 0.1 OCM2 ENSG00000135175 "Oncomodulin 2" P0CE71 7 97984684-97991169 "Predicted intracellular proteins" "No human protein/transcript evidence" "No human protein/transcript evidence" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046422, HPA052483" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA046422: AB_2679659, HPA052483: " 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 ODC1 ODC ENSG00000115758 "Ornithine decarboxylase 1" P11926 2 10439968-10448327 "Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Polyamine biosynthesis" "Decarboxylase, Lyase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 560.8;Late spermatids: 834.9;Prostatic glandular cells: 412.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001536, CAB035996" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "CAB035996: , HPA001536: AB_1079521" "unprognostic (2.33e-1)" "unprognostic (3.41e-1)" "unprognostic (7.25e-3)" "unprognostic (5.21e-3)" "unprognostic (4.22e-2)" "unprognostic (2.70e-1)" "prognostic unfavorable (3.07e-5)" "unprognostic (3.06e-2)" "unprognostic (4.18e-2)" "unprognostic (6.27e-2)" "unprognostic (3.04e-1)" "unprognostic (6.65e-2)" "unprognostic (1.67e-3)" "unprognostic (1.18e-1)" "unprognostic (1.05e-1)" "unprognostic (2.26e-2)" "unprognostic (5.86e-2)" 47.2 23.2 31.0 69.3 31.5 172.9 33.0 30.5 32.2 33.5 48.5 64.8 32.4 66.0 49.2 29.4 56.3 43.7 55.9 29.9 33.0 132.2 92.1 52.4 111.0 32.4 33.0 54.8 61.8 99.6 92.5 20.0 30.6 91.1 72.0 46.2 27.0 55.1 163.3 29.2 41.6 71.2 34.1 42.9 51.5 133.3 34.0 77.1 58.5 73.5 149.1 113.6 26.9 35.7 166.8 130.6 177.1 211.4 31.1 92.4 410.1 234.6 114.9 216.3 99.9 697.3 75.4 870.2 114.6 143.6 208.6 30.2 549.1 265.5 261.2 334.0 231.5 398.1 212.2 429.9 250.8 680.1 91.8 62.5 70.5 490.1 608.3 111.4 176.3 237.6 674.2 274.3 121.7 109.0 680.1 267.3 324.9 228.3 418.8 478.5 556.0 586.3 130.9 119.5 246.6 209.9 293.6 88.8 121.8 135.7 60.0 300.5 124.7 174.4 362.6 227.9 511.7 128.0 416.1 780.8 156.7 443.6 109.9 0.0 1.5 3.0 2.9 2.9 3.3 14.8 4.1 4.8 3.4 15.0 2.8 4.5 0.5 1.4 1.8 12.2 4.4 3.2 31.0 31.5 30.5 32.2 29.9 33.0 32.4 33.0 30.6 34.1 34.0 35.7 78.2 44.8 161.4 7.5 228.9 58.0 123.7 48.8 19.4 36.8 53.2 68.3 55.1 81.5 33.9 40.5 31.3 1.5 188.1 77.7 72.4 50.6 560.8 90.9 66.2 52.2 271.0 111.3 7.5 27.6 70.0 63.2 204.4 127.6 58.9 103.8 14.6 50.3 46.8 6.7 4.1 234.1 22.4 32.1 22.4 834.9 15.5 191.8 23.2 8.4 22.1 126.3 37.0 4.5 2.4 28.6 64.5 11.3 287.4 412.4 31.6 154.1 21.9 77.4 0.0 223.0 79.9 186.5 75.8 52.2 87.5 3.4 133.0 30.2 180.5 142.2 ODR4 "C1orf27, FLJ20505, odr-4, TTG1" ENSG00000157181 "Odr-4 GPCR localization factor homolog" Q5SWX8 1 186375838-186421378 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 37.8;Glandular and luminal cells: 38.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015988, HPA031352" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 29: Non-specific - Vesicular transport" "Cluster 21: OE19 - Mitochondria" "Cluster 7: Non-specific - Mitochondria" "Nucleoplasm, Plasma membrane" "HPA015988: AB_1845644, HPA031352: AB_2673838" "unprognostic (1.19e-2)" "unprognostic (4.23e-2)" "unprognostic (1.12e-2)" "unprognostic (3.07e-2)" "unprognostic (1.08e-1)" "unprognostic (1.30e-2)" "unprognostic (2.11e-1)" "unprognostic (8.57e-2)" "unprognostic (8.11e-3)" "prognostic favorable (9.92e-4)" "unprognostic (1.15e-2)" "unprognostic (9.85e-2)" "unprognostic (2.18e-2)" "unprognostic (1.34e-1)" "unprognostic (3.50e-2)" "unprognostic (1.03e-2)" "unprognostic (4.20e-2)" 11.9 14.4 7.5 7.2 9.2 15.0 14.0 10.4 10.1 13.3 8.4 10.8 13.4 9.4 17.2 7.8 8.8 10.6 10.0 7.6 8.2 16.7 21.8 9.5 6.7 8.9 8.6 10.3 29.1 32.4 12.4 14.2 9.2 16.6 12.7 15.2 21.7 12.2 9.0 10.3 13.6 8.8 8.7 8.5 13.1 8.3 8.2 6.4 19.9 9.5 7.1 11.5 8.2 11.9 12.6 13.9 15.1 12.1 17.5 16.3 28.8 19.9 12.2 12.7 12.8 28.2 29.7 8.7 23.5 9.9 11.6 32.3 11.4 10.9 12.5 7.1 10.9 8.2 17.7 15.9 16.4 13.8 9.6 12.5 21.3 15.4 24.1 13.2 13.8 9.0 32.1 17.3 15.3 13.5 9.7 14.3 21.6 46.0 5.0 11.2 10.5 25.0 26.1 12.9 11.0 17.2 15.1 33.0 24.5 26.9 29.1 12.4 13.2 18.1 11.5 12.2 18.9 20.2 13.3 13.3 9.8 7.4 16.7 1.4 9.0 2.5 3.0 8.9 4.5 3.6 3.8 4.2 7.6 2.3 4.7 3.6 3.9 10.0 11.4 4.8 5.7 3.9 7.5 9.2 10.4 10.1 7.6 8.2 8.9 8.6 9.2 8.7 8.2 11.9 28.1 28.9 37.8 0.0 4.2 0.0 0.0 0.0 0.0 0.0 18.8 16.5 0.0 0.0 29.7 25.8 0.0 22.0 12.6 0.0 9.8 22.8 0.0 26.8 27.0 9.8 0.0 0.0 0.0 25.4 25.7 12.3 0.0 38.6 12.6 26.4 0.0 0.0 15.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.7 0.0 0.0 6.7 0.0 0.0 0.0 0.0 24.7 0.0 0.0 4.0 0.0 0.0 10.7 15.3 0.0 0.0 0.0 9.4 0.0 0.0 0.0 0.0 28.0 6.9 29.0 0.0 0.0 OGT "FLJ23071, HRNT1, MGC22921, O-GLCNAC, OGT1" ENSG00000147162 "O-linked N-acetylglucosamine (GlcNAc) transferase" O15294 X 71533104-71575892 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Biological rhythms, Host-virus interaction, Ubl conjugation pathway" "Chromatin regulator, Glycosyltransferase, Transferase" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030751, HPA030752, HPA030753, HPA030754, CAB034099" Approved Supported "Nucleoplasm,Plasma membrane" Yes No "Cluster 39: Non-specific - mRNA processing" "Cluster 50: Non-specific - Ribosome" "Cluster 2: Karpas-707 - Immune response" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "CAB034099: AB_2157067, HPA030751: AB_10600217, HPA030752: AB_10601445, HPA030753: AB_2673594, HPA030754: AB_2673595" "unprognostic (1.37e-1)" "unprognostic (2.20e-1)" "unprognostic (2.32e-2)" "prognostic unfavorable (8.33e-4)" "unprognostic (3.40e-2)" "prognostic favorable (1.97e-4)" "unprognostic (9.56e-3)" "unprognostic (1.96e-3)" "unprognostic (5.58e-2)" "unprognostic (2.29e-1)" "unprognostic (1.06e-1)" "unprognostic (9.74e-3)" "prognostic unfavorable (2.36e-6)" "unprognostic (2.99e-3)" "unprognostic (2.28e-1)" "unprognostic (8.03e-3)" "prognostic favorable (6.85e-7)" 59.3 55.9 39.7 38.3 42.4 61.5 62.7 43.3 51.6 72.7 40.1 62.5 30.6 56.0 62.2 52.8 76.4 26.4 55.5 43.9 35.5 61.6 45.8 70.7 71.9 36.1 35.8 85.5 102.4 24.3 46.9 26.4 37.9 75.4 39.6 36.9 64.1 27.1 62.8 68.6 86.4 24.5 36.1 122.8 67.4 19.0 36.2 57.2 70.7 39.2 57.8 55.7 67.4 44.3 40.5 37.0 47.1 41.5 49.6 45.6 31.6 30.3 54.3 32.1 49.1 39.3 45.4 47.9 20.7 37.3 33.3 49.1 52.0 29.5 39.4 41.1 53.4 30.4 98.6 28.5 37.6 62.9 48.1 43.6 59.2 35.1 65.7 55.5 30.5 100.7 31.1 160.4 31.1 34.3 48.9 75.2 31.6 35.5 49.8 47.8 52.7 62.1 50.0 45.9 24.1 21.2 46.9 30.9 30.2 35.5 22.8 42.4 35.5 34.6 27.9 36.6 17.9 43.5 33.5 56.5 24.4 65.0 21.6 2.8 4.6 2.0 7.5 5.7 6.8 7.4 6.3 6.2 6.1 6.2 7.2 7.4 1.9 10.4 5.7 6.2 6.2 5.6 39.7 42.4 43.3 51.6 43.9 35.5 36.1 35.8 37.9 36.1 36.2 44.3 31.1 35.3 85.2 52.9 67.2 88.1 37.9 23.5 58.6 26.5 49.6 34.0 42.8 20.0 31.1 49.7 8.4 15.8 130.7 31.1 9.8 14.4 2.4 32.1 49.8 39.8 34.9 51.3 110.7 14.4 8.5 47.5 54.6 53.3 27.8 26.4 45.7 27.5 16.1 40.4 94.6 37.3 22.4 60.9 69.7 4.8 53.4 45.8 35.6 71.2 51.6 11.3 51.5 92.0 97.9 17.6 34.9 29.7 147.2 53.8 34.8 15.1 28.0 21.8 32.9 44.8 42.2 2.5 6.1 63.3 84.1 10.9 82.1 62.0 34.0 50.8 OLIG2 "BHLHB1, bHLHe19, OLIGO2, PRKCBP2, RACK17" ENSG00000205927 "Oligodendrocyte transcription factor 2" Q13516 21 33025935-33029196 "Cancer-related genes, Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding" "Cancer-related genes, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "brain: 87.2" "Group enriched" "Detected in some" 22 "Oligodendrocyte precursor cells: 124.1;Oligodendrocytes: 39.9" "Cancer enriched" "Detected in some" 52 "glioma: 46.9" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "eosinophil: 19.0" "Lineage enriched" "Detected in single" 190 "granulocytes: 19.0" "Cell line enhanced" "Detected in some" "HMC-1: 56.2;NB-4: 41.8;THP-1: 35.9;WM-115: 11.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003254, CAB019381" Enhanced Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 3: HMC-1 - Innate immune response" "Cluster 68: Oligodendrocytes - Mixed function" Nucleoplasm "Plasma membrane" "CAB019381: , HPA003254: AB_1854795" "unprognostic (5.14e-1)" "unprognostic (4.56e-1)" "unprognostic (1.44e-2)" "unprognostic (8.27e-2)" "unprognostic (3.24e-2)" "unprognostic (4.34e-2)" "unprognostic (4.81e-2)" "unprognostic (5.41e-2)" "unprognostic (1.39e-1)" "unprognostic (5.78e-5)" "unprognostic (2.76e-1)" 0.0 0.0 46.4 0.0 58.3 0.0 0.0 52.7 54.4 0.0 21.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 48.1 49.8 0.0 0.0 0.0 0.0 58.0 54.6 0.0 0.0 0.0 0.1 0.0 51.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 48.0 0.0 0.1 0.0 50.9 0.0 0.0 0.2 0.0 0.0 0.0 87.2 0.0 0.0 0.1 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 6.5 0.0 0.0 0.0 1.1 8.2 0.0 0.0 0.0 1.7 56.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 41.8 3.6 0.0 0.0 0.0 2.9 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 35.9 0.0 0.0 4.4 0.0 0.0 0.1 0.0 0.0 1.4 0.0 11.7 2.8 0.0 19.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 46.4 58.3 52.7 54.4 48.1 49.8 58.0 54.6 51.4 48.0 50.9 87.2 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 124.1 39.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 OPHN1 "ARHGAP41, MRX60, OPN1" ENSG00000079482 "Oligophrenin 1" O60890 X 67949349-68433913 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Endocytosis, Neurogenesis" "GTPase activation" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 20.8" "Group enriched" "Detected in many" 5 "Astrocytes: 383.9;Oligodendrocyte precursor cells: 600.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 4.6" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 23.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA002919 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 6: Brain - Smell perception" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Nucleoplasm, Plasma membrane" "HPA002919: AB_1079526" "unprognostic (1.21e-1)" "unprognostic (3.21e-2)" "unprognostic (1.96e-1)" "unprognostic (7.31e-2)" "unprognostic (3.85e-3)" "unprognostic (4.32e-2)" "unprognostic (3.52e-2)" "unprognostic (3.09e-3)" "unprognostic (2.22e-1)" "unprognostic (6.62e-2)" "unprognostic (4.37e-2)" "unprognostic (2.30e-1)" "unprognostic (2.21e-4)" "unprognostic (1.98e-1)" "unprognostic (1.29e-2)" "unprognostic (2.08e-3)" "unprognostic (2.64e-3)" 4.1 5.1 20.8 1.8 18.6 3.9 4.5 14.2 19.5 6.0 1.0 3.4 2.5 5.6 3.7 3.8 3.2 2.7 3.1 18.0 14.6 4.3 1.3 4.4 1.9 9.5 11.9 4.5 3.1 3.6 2.7 5.6 5.8 10.1 3.4 11.5 5.4 5.0 6.5 6.4 2.9 4.0 6.1 2.3 3.8 2.6 16.3 1.2 4.7 4.8 1.4 2.3 3.8 11.5 23.6 5.1 3.2 7.3 7.1 6.8 5.0 4.2 5.6 8.3 10.1 3.3 4.5 1.5 13.7 4.9 3.4 5.7 3.1 2.9 12.6 0.9 2.1 5.2 6.9 3.7 2.4 2.1 5.2 4.6 4.8 6.9 6.4 10.6 5.6 1.1 3.2 3.1 4.3 10.1 0.8 1.8 7.5 10.0 4.8 0.9 7.3 1.3 8.5 7.6 1.7 2.8 7.2 9.1 13.7 7.1 6.2 1.6 6.0 5.0 7.3 18.1 4.5 2.9 3.4 1.0 4.0 2.8 3.5 1.0 1.0 0.4 0.5 0.4 0.4 0.5 0.4 0.3 0.4 0.8 0.4 0.5 4.6 0.5 0.6 1.6 0.3 0.2 20.8 18.6 14.2 19.5 18.0 14.6 9.5 11.9 5.8 6.1 16.3 11.5 13.8 16.0 19.3 383.9 0.0 3.2 5.4 2.0 10.2 5.4 6.7 5.0 3.3 2.8 6.4 18.4 6.2 23.0 2.3 3.9 0.0 1.2 2.0 7.2 4.3 8.1 4.2 1.3 84.6 0.8 11.7 18.0 14.8 12.9 8.8 36.3 5.0 0.2 4.6 0.0 78.8 3.0 2.0 2.1 9.5 1.7 21.1 5.9 8.8 54.4 1.2 16.0 3.1 600.2 41.7 1.3 2.4 12.0 0.1 8.5 3.8 1.8 10.9 5.1 0.0 24.1 5.4 0.3 1.9 8.9 5.1 66.9 1.4 4.2 4.1 4.2 OR13C2 ENSG00000276119 "Olfactory receptor family 13 subfamily C member 2" Q8NGS9 9 104604671-104605627 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.8 0.3 0.0 0.0 0.0 0.4 0.0 0.9 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.1 0.2 0.8 0.3 0.9 0.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C5 ENSG00000277556 "Olfactory receptor family 13 subfamily C member 5" Q8NGS8 9 104598457-104599413 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Supported "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " "unprognostic (4.88e-2)" 0.0 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.5 0.0 0.0 0.0 0.0 0.5 0.4 0.0 0.1 0.0 0.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.3 0.0 0.3 0.2 0.5 0.5 0.4 0.8 0.0 0.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR13C9 ENSG00000136839 "Olfactory receptor family 13 subfamily C member 9" Q8NGT0 9 104617248-104618204 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA078297 Uncertain "Nucleoplasm,Plasma membrane" NA NA "Plasma membrane" Nucleoplasm "HPA078297: " 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.2 0.2 0.1 0.3 0.4 0.5 0.1 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6B2 OR6B2P ENSG00000182083 "Olfactory receptor family 6 subfamily B member 2" Q6IFH4 2 240028965-240030456 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6B3 "OR6B3P, OR6B3Q" ENSG00000178586 "Olfactory receptor family 6 subfamily B member 3" Q8NGW1 2 240045077-240047027 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "Evidence at transcript level" "No human protein/transcript evidence" "Evidence at transcript level" "Tissue enriched" "Detected in some" 13 "retina: 20.9" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047529 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 77: Retina - Visual perception" "Plasma membrane" Cytosol "HPA047529: AB_2680077" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OR6C6 ENSG00000188324 "Olfactory receptor family 6 subfamily C member 6" A6NF89 12 55293988-55296569 "G-protein coupled receptors, Predicted membrane proteins" "Olfaction, Sensory transduction" "G-protein coupled receptor, Receptor, Transducer" "Evidence at transcript level" "No human protein/transcript evidence" "No human protein/transcript evidence" "Evidence at transcript level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA051090 Uncertain Approved "Lipid droplets,Plasma membrane" NA NA "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Lipid droplets, Plasma membrane" "HPA051090: AB_2681341" 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 OSGEP "GCPL1, KAE1, OSGEP1, PRSMG1, TCS3" ENSG00000092094 "O-sialoglycoprotein endopeptidase" Q9NPF4 14 20446401-20455089 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "tRNA processing" "Acyltransferase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039751 Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 23: Antigen presenting cells - Antigen presentation" "Cluster 52: Non-specific - Ribosome" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 57: B-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA039751: AB_10794754" "prognostic favorable (1.48e-4)" "unprognostic (4.15e-3)" "unprognostic (1.29e-1)" "unprognostic (4.33e-3)" "unprognostic (1.54e-2)" "unprognostic (3.95e-2)" "unprognostic (5.54e-3)" "unprognostic (2.80e-3)" "unprognostic (2.98e-1)" "unprognostic (1.05e-1)" "unprognostic (3.35e-3)" "unprognostic (1.22e-1)" "prognostic unfavorable (4.64e-6)" "unprognostic (4.83e-2)" "unprognostic (1.86e-2)" "unprognostic (2.53e-2)" "unprognostic (9.91e-2)" 5.7 6.3 6.1 3.8 6.2 6.1 7.0 6.4 7.3 6.8 6.8 7.6 3.8 6.4 8.5 6.0 6.1 6.6 8.1 6.0 6.3 5.8 11.1 6.2 9.3 6.4 6.1 5.3 5.6 7.4 5.2 6.7 6.4 4.9 7.0 4.1 5.3 8.3 10.5 4.7 6.2 5.6 6.5 8.4 6.4 2.4 6.3 9.9 7.6 9.9 10.1 8.2 4.9 6.9 10.3 17.2 5.6 16.2 9.9 6.6 17.6 8.0 11.3 21.1 20.1 21.5 12.3 21.1 10.3 11.0 9.0 8.6 17.9 17.6 14.1 16.8 19.1 14.8 12.2 32.1 7.4 24.3 19.7 5.3 5.2 26.1 14.0 4.6 14.3 18.8 14.0 12.1 17.6 21.0 25.0 11.8 9.1 31.5 31.8 35.3 10.3 12.4 12.8 11.7 21.3 4.2 15.4 16.0 11.9 3.3 9.7 23.7 6.1 8.7 21.2 11.3 10.7 3.4 18.0 31.7 5.0 36.1 11.0 9.3 29.2 38.5 18.8 27.9 17.4 28.7 19.7 17.2 44.5 38.1 15.9 17.4 13.8 20.9 23.3 16.9 19.2 24.6 6.1 6.2 6.4 7.3 6.0 6.3 6.4 6.1 6.4 6.5 6.3 6.9 27.1 35.3 34.9 16.3 46.0 11.5 20.9 26.2 14.2 37.8 24.0 25.1 17.2 15.7 29.1 23.9 37.5 66.3 31.8 22.5 35.2 24.7 3.1 19.2 18.3 24.1 26.9 19.6 23.0 29.8 47.0 23.4 28.1 16.3 25.9 24.6 25.7 19.3 65.8 10.1 24.1 24.2 22.4 30.7 32.8 3.0 19.3 34.2 21.4 7.5 28.4 31.0 32.0 16.6 17.0 20.0 30.6 21.4 26.2 10.9 42.2 39.7 25.5 51.5 13.1 24.6 23.9 7.8 16.9 22.0 11.5 46.1 26.8 37.3 31.6 17.4 OSR2 FLJ90037 ENSG00000164920 "Odd-skipped related transciption factor 2" Q8N2R0 8 98944403-98952104 "Predicted intracellular proteins, Transcription factors" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "cervix: 166.1;endometrium 1: 155.1;fallopian tube: 155.3" "Group enriched" "Detected in many" 4 "Endometrial stromal cells: 243.1;Leydig cells: 784.1;Peritubular cells: 758.3" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 16 "ASC diff: 542.4" "Not detected" "Not detected" "Not detected" "Not detected" "HPA052425, HPA063486" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 36: Stromal cells - Cell proliferation" "Plasma membrane" Nucleoplasm "HPA052425: AB_2681826, HPA063486: AB_2685022" "unprognostic (1.72e-1)" "unprognostic (1.92e-3)" "unprognostic (1.03e-1)" "unprognostic (5.94e-2)" "unprognostic (1.57e-1)" "prognostic favorable (2.44e-5)" "unprognostic (1.70e-2)" "unprognostic (1.15e-2)" "unprognostic (1.89e-2)" "unprognostic (3.73e-3)" "unprognostic (3.01e-2)" "unprognostic (6.19e-2)" "unprognostic (1.57e-7)" "unprognostic (1.37e-2)" "unprognostic (2.39e-1)" "unprognostic (2.56e-4)" "unprognostic (8.54e-3)" 45.0 9.9 0.0 2.4 0.0 0.6 26.0 0.2 0.2 166.1 0.0 9.2 0.6 155.1 53.7 15.1 155.3 12.9 4.2 0.0 0.0 1.3 0.3 3.6 2.4 0.0 0.0 93.2 4.2 3.0 2.7 8.2 0.0 40.2 3.8 0.0 6.8 72.2 5.6 27.9 24.9 47.1 0.0 0.2 5.1 35.6 0.0 0.8 5.6 5.1 1.1 27.2 83.8 0.0 32.3 4.5 0.0 4.4 542.4 17.2 4.3 17.6 33.1 13.7 13.6 3.4 3.9 0.0 2.9 26.7 0.8 12.4 2.7 4.7 6.7 1.5 13.0 0.6 3.3 1.6 8.9 0.9 0.6 17.0 9.8 2.3 1.6 0.8 0.0 4.8 4.0 0.4 0.6 14.6 2.9 5.7 0.0 2.6 2.8 13.8 1.6 1.1 1.1 2.7 1.4 0.1 1.9 7.5 0.4 0.3 4.3 7.5 0.2 2.1 0.1 13.9 1.0 0.7 0.5 0.3 0.9 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.4 0.0 0.0 0.0 0.9 14.1 6.6 3.4 1.2 0.0 7.9 5.3 0.7 0.0 3.3 0.0 0.0 17.2 0.9 0.7 0.0 0.0 5.8 7.8 243.1 3.7 0.0 0.0 0.0 0.0 138.4 71.7 0.5 5.9 0.0 0.2 0.0 0.0 9.3 0.0 0.0 18.4 10.2 1.9 21.9 24.1 784.1 2.7 16.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.8 758.3 4.6 3.6 103.9 0.1 1.7 0.0 32.9 8.8 21.3 5.1 4.5 0.3 9.1 24.2 2.3 95.6 22.3 2.2 OTULIN "FAM105B, FLJ34884" ENSG00000154124 "OTU deubiquitinase with linear linkage specificity" Q96BN8 5 14664664-14699850 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Immunity, Innate immunity, Ubl conjugation pathway, Wnt signaling pathway" "Hydrolase, Protease, Thiol protease" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 26.8" "Cell type enhanced" "Detected in many" "dendritic cells: 70.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA051074 Uncertain Approved "Plasma membrane,Mitochondria" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 20: HeLa - Mitochondria" "Cluster 24: Non-specific - Transcription regulation" Mitochondria "Plasma membrane" "HPA051074: AB_2681334" "unprognostic (4.81e-3)" "unprognostic (1.11e-1)" "unprognostic (4.00e-2)" "unprognostic (1.19e-2)" "unprognostic (7.48e-2)" "unprognostic (1.91e-2)" "unprognostic (7.94e-3)" "unprognostic (1.43e-1)" "unprognostic (2.48e-2)" "unprognostic (9.55e-2)" "unprognostic (1.02e-1)" "unprognostic (7.13e-2)" "prognostic unfavorable (2.59e-7)" "unprognostic (2.92e-2)" "unprognostic (2.28e-2)" "unprognostic (1.60e-1)" "unprognostic (5.02e-2)" 5.0 3.9 4.8 9.6 6.3 26.8 4.6 5.9 4.9 5.5 6.2 4.7 7.6 3.6 2.6 8.0 3.5 4.7 6.7 4.9 5.0 4.4 12.3 6.4 12.5 6.6 5.6 4.8 6.8 3.8 3.6 6.5 6.4 6.3 4.6 4.6 5.7 3.3 5.2 11.8 5.8 4.8 5.6 7.1 4.3 7.1 5.8 11.2 4.1 5.5 13.5 5.7 6.9 7.1 10.0 11.5 11.2 12.8 10.0 10.3 12.3 9.8 6.9 13.8 10.2 15.4 7.2 18.0 18.9 6.4 19.9 11.1 14.1 12.9 9.2 31.1 11.6 12.9 36.3 8.3 8.8 12.4 21.2 6.0 15.2 11.3 9.4 7.6 11.8 14.9 13.0 27.8 10.0 6.1 12.4 10.6 6.9 10.5 12.0 18.8 10.0 7.1 8.9 10.1 5.1 8.3 35.1 7.8 7.6 13.5 8.5 14.1 11.1 17.8 20.0 13.4 13.2 12.4 20.6 20.3 10.1 23.2 9.3 0.2 0.6 1.1 0.3 0.7 1.0 0.3 0.8 1.1 1.0 1.6 0.5 1.3 0.7 0.3 1.1 0.8 1.7 0.3 4.8 6.3 5.9 4.9 4.9 5.0 6.6 5.6 6.4 5.6 5.8 7.1 20.3 3.2 11.5 23.5 24.6 0.0 23.2 0.0 26.2 11.9 12.8 11.7 15.0 10.0 4.3 5.5 14.6 15.1 70.6 21.1 7.9 5.5 9.4 20.6 28.1 13.3 9.5 13.7 18.5 5.8 10.3 10.1 16.8 24.0 10.2 14.0 6.4 36.9 13.9 8.4 19.5 15.7 0.0 18.9 0.0 4.2 10.5 25.0 0.0 38.4 17.1 10.4 26.8 16.6 31.7 8.0 13.3 6.4 38.5 25.9 14.1 15.1 5.1 31.4 0.0 11.5 10.2 29.7 28.8 23.7 0.0 14.2 35.8 7.6 15.6 23.1 PACSIN3 SDPIII ENSG00000165912 "Protein kinase C and casein kinase substrate in neurons 3" Q9UKS6 11 47177522-47186443 "Plasma proteins, Predicted intracellular proteins" Endocytosis "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "heart muscle: 161.8;skeletal muscle: 480.9;tongue: 279.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 112.0;Extravillous trophoblasts: 60.6;Muller glia cells: 63.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "T-47d: 127.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039480, HPA043904" Approved Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 20: HeLa - Mitochondria" "Cluster 54: Cardiomyocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA039480: AB_2676531, HPA043904: AB_2678725" "unprognostic (1.75e-1)" "unprognostic (1.11e-1)" "unprognostic (1.73e-2)" "unprognostic (3.10e-2)" "unprognostic (1.21e-1)" "unprognostic (6.89e-2)" "unprognostic (4.66e-2)" "unprognostic (8.17e-2)" "unprognostic (2.85e-1)" "prognostic favorable (2.09e-4)" "unprognostic (3.86e-3)" "unprognostic (1.26e-1)" "unprognostic (2.75e-2)" "unprognostic (9.72e-2)" "unprognostic (1.92e-1)" "unprognostic (1.29e-1)" "unprognostic (4.76e-2)" 14.4 66.5 19.6 4.5 28.2 0.4 18.4 24.5 20.9 33.3 18.8 50.2 4.7 33.5 11.4 52.6 29.1 7.2 161.8 18.0 19.4 14.8 43.6 15.9 2.0 33.8 27.5 23.2 33.1 11.0 6.2 16.1 32.1 35.2 2.7 4.5 40.8 20.6 480.9 41.4 11.3 21.2 25.0 4.5 33.5 4.5 25.4 2.0 24.5 279.4 5.2 21.5 31.8 39.0 56.4 27.1 12.5 51.5 10.3 10.2 59.8 19.4 24.6 33.9 19.1 40.8 7.3 0.3 5.9 9.2 23.0 90.0 23.7 40.2 13.0 8.7 44.8 8.4 105.5 91.7 19.9 2.0 8.4 28.2 52.3 17.9 28.3 27.2 15.3 15.2 18.4 0.7 13.9 106.7 0.7 40.8 15.5 43.7 58.7 33.1 48.0 9.0 14.3 49.3 0.3 42.6 28.2 17.9 24.6 24.6 127.3 6.9 6.9 57.6 62.5 7.5 47.1 10.1 4.4 5.3 18.6 19.2 30.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 19.6 28.2 24.5 20.9 18.0 19.4 33.8 27.5 32.1 25.0 25.4 39.0 6.1 0.0 8.1 4.9 0.3 35.9 29.1 25.1 30.7 0.7 32.2 24.3 112.0 38.6 18.1 5.5 0.0 31.0 0.6 0.2 9.8 37.7 0.0 3.1 8.4 7.8 0.0 2.7 0.8 15.5 60.6 12.6 9.7 6.2 0.0 3.0 8.6 33.1 6.0 0.0 1.1 0.2 14.2 1.6 4.6 0.4 16.1 1.0 17.8 2.8 0.0 63.6 0.0 0.0 9.5 41.0 0.0 12.4 2.6 56.8 1.5 24.3 5.0 3.2 32.9 18.5 25.4 0.2 7.5 39.7 29.8 18.3 0.7 4.8 1.4 29.8 PAG1 "CBP, PAG" ENSG00000076641 "Phosphoprotein membrane anchor with glycosphingolipid microdomains 1" Q9NWQ8 8 80967810-81112068 "Predicted intracellular proteins" "Adaptive immunity, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Distal enterocytes: 169.6;granulocytes: 124.5;Melanocytes: 140.5;Microglial cells: 166.8;Sertoli cells: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 35.4;HMC-1: 45.5;SK-MEL-30: 36.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA001632, HPA066527" Enhanced Supported "Vesicles,Plasma membrane" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 41: Macrophages - Immune response" "Vesicles, Plasma membrane" "HPA001632: AB_1079557, HPA066527: AB_2685685" "unprognostic (8.30e-2)" "unprognostic (3.84e-2)" "unprognostic (5.89e-2)" "unprognostic (4.79e-2)" "unprognostic (1.55e-1)" "unprognostic (6.91e-2)" "unprognostic (3.71e-3)" "unprognostic (3.84e-2)" "unprognostic (3.73e-2)" "unprognostic (4.52e-2)" "unprognostic (2.93e-1)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.24e-6)" "unprognostic (2.12e-1)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.80e-1)" "unprognostic (1.94e-3)" 3.9 3.1 3.4 9.0 3.5 12.3 2.0 14.8 4.0 1.8 4.3 9.2 7.6 1.9 2.2 1.6 1.8 7.1 4.7 2.8 3.7 1.7 4.7 14.9 14.5 4.5 4.5 1.2 14.9 0.9 2.0 16.0 4.9 2.6 8.7 5.0 3.7 2.1 1.3 4.3 9.0 3.0 4.9 9.1 4.4 0.7 5.2 10.4 1.8 2.1 14.0 4.8 2.6 5.6 0.1 0.1 4.8 0.2 8.9 8.5 0.1 2.0 15.5 1.0 1.9 0.3 0.1 35.4 0.2 0.5 7.6 1.5 0.1 1.8 0.9 0.9 4.5 20.8 0.3 0.0 9.1 3.4 45.5 4.1 1.2 8.9 8.2 0.9 0.0 6.2 0.2 0.1 14.8 0.3 12.6 0.3 0.4 8.1 1.4 9.5 2.4 0.1 1.6 7.6 1.0 1.7 0.0 0.3 36.1 0.8 1.2 3.5 0.3 1.1 0.6 0.0 1.2 5.7 1.6 12.3 9.7 11.7 8.5 13.1 1.4 2.0 2.5 6.4 6.1 2.0 6.2 4.4 1.9 1.6 4.9 3.8 2.3 1.7 14.6 4.1 7.2 2.7 3.4 3.5 14.8 4.0 2.8 3.7 4.5 4.5 4.9 4.9 5.2 5.6 6.2 0.0 12.4 40.8 37.0 31.5 3.9 5.2 0.6 39.7 2.2 2.2 15.4 10.0 14.0 3.7 0.0 0.8 39.0 169.6 0.0 4.0 3.5 0.6 4.4 10.9 3.6 3.8 57.5 6.5 26.2 24.3 8.2 1.1 124.5 97.0 12.5 10.3 27.1 63.9 60.0 23.2 6.1 73.6 26.2 2.1 2.5 79.1 140.5 166.8 40.8 34.9 19.6 82.4 75.3 2.0 62.1 7.9 38.4 7.7 109.3 0.4 0.8 3.2 124.9 32.3 37.1 0.2 3.0 3.8 22.6 2.3 78.1 11.8 27.4 13.7 PAIP1 ENSG00000172239 "Poly(A) binding protein interacting protein 1" Q9H074 5 43526267-43557758 "Predicted intracellular proteins" "Translation regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA073653, HPA076187" Approved Enhanced "Plasma membrane,Cytosol" No No 60000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 8: Non-specific - Mitochondria" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cytosol" "HPA073653: AB_2732234, HPA076187: AB_2686784" "unprognostic (4.70e-2)" "unprognostic (4.30e-2)" "unprognostic (5.37e-2)" "unprognostic (2.65e-2)" "unprognostic (1.62e-2)" "unprognostic (4.74e-2)" "unprognostic (1.13e-3)" "unprognostic (2.98e-1)" "unprognostic (3.17e-2)" "unprognostic (1.62e-2)" "prognostic unfavorable (4.79e-4)" "unprognostic (3.54e-1)" "unprognostic (1.73e-1)" "unprognostic (1.39e-1)" "unprognostic (1.20e-1)" "unprognostic (1.52e-1)" "unprognostic (1.30e-1)" 69.5 54.3 47.8 36.6 50.8 56.6 67.4 52.0 64.2 65.1 52.0 57.1 43.3 61.6 57.3 52.0 51.2 53.3 92.5 51.2 52.0 78.0 90.9 50.3 39.4 49.5 49.5 53.7 54.8 74.3 29.3 68.1 50.8 69.1 54.8 95.2 51.3 68.5 155.3 31.1 40.2 65.3 54.3 34.2 46.9 83.6 49.0 47.6 73.6 122.9 45.3 70.1 39.9 56.5 94.5 82.2 158.0 153.7 161.8 127.1 129.1 81.2 180.0 151.5 130.9 77.2 112.8 62.5 136.9 115.5 227.3 60.4 249.3 98.0 153.5 52.2 96.7 49.2 157.1 122.6 142.3 74.2 74.3 135.8 186.1 102.5 191.7 153.1 146.8 45.9 115.9 82.1 153.0 101.7 82.4 101.8 78.5 89.4 104.8 63.8 119.2 88.1 188.8 114.3 89.4 135.3 260.3 99.2 190.0 144.0 141.4 106.3 82.4 136.6 112.5 68.8 103.7 61.7 112.6 94.3 79.7 113.1 120.4 40.4 24.1 46.2 18.9 20.7 25.2 26.4 23.2 26.2 23.7 26.7 28.9 23.2 8.6 24.9 22.5 66.8 23.0 22.1 47.8 50.8 52.0 64.2 51.2 52.0 49.5 49.5 50.8 54.3 49.0 56.5 66.4 32.1 52.2 15.0 39.4 73.3 74.0 78.5 52.3 48.8 78.8 53.1 122.4 78.6 52.7 44.1 20.9 76.3 66.0 33.1 158.5 120.3 182.6 73.8 56.4 71.2 44.9 54.9 30.0 91.6 89.2 64.2 39.3 55.9 24.6 47.4 50.0 49.2 59.4 35.3 25.3 52.1 103.7 40.9 39.7 58.0 76.4 42.0 83.6 20.6 53.8 86.6 24.7 26.7 35.1 116.4 43.8 66.5 43.3 106.4 45.1 148.8 40.9 67.7 26.3 70.2 71.4 171.2 76.6 56.0 66.3 68.1 35.1 49.7 47.7 84.3 PAK1 ENSG00000149269 "P21 (RAC1) activated kinase 1" Q13153 11 77322017-77474635 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Exocytosis" "Allosteric enzyme, Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Epilepsy, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Excitatory neurons: 219.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Group enriched" "Detected in all" 9 "classical monocyte: 182.2;eosinophil: 292.7;intermediate monocyte: 177.7;myeloid DC: 264.3;neutrophil: 431.8;non-classical monocyte: 202.6" "Group enriched" "Detected in all" 11 "dendritic cells: 264.3;granulocytes: 431.8;monocytes: 202.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003565, CAB005312" Enhanced Supported Supported "Plasma membrane,Cytosol" NA NA 560000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 29: U-266 - Adaptive immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB005312: AB_2160720, HPA003565: AB_1854935" "unprognostic (1.15e-2)" "unprognostic (3.23e-2)" "prognostic favorable (5.87e-4)" "unprognostic (1.30e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (6.62e-2)" "unprognostic (8.19e-3)" "unprognostic (4.84e-2)" "unprognostic (1.05e-1)" "unprognostic (1.22e-3)" "unprognostic (1.86e-2)" "unprognostic (2.76e-1)" "unprognostic (1.02e-1)" "unprognostic (6.91e-2)" "unprognostic (1.57e-1)" "unprognostic (4.00e-3)" "unprognostic (1.52e-2)" 12.7 13.4 32.4 33.9 44.5 59.0 18.2 13.9 57.7 21.1 0.0 43.2 43.1 20.9 29.8 21.4 21.9 30.9 9.4 58.3 8.0 26.1 14.5 16.8 20.4 19.2 12.2 21.1 17.5 20.5 20.7 14.7 19.4 19.1 46.5 25.1 19.9 19.7 87.0 16.2 45.7 27.0 0.9 29.3 41.2 25.7 17.1 29.1 40.6 18.8 23.1 27.7 20.7 30.0 39.9 26.7 56.7 25.5 22.8 37.6 45.9 44.6 32.1 42.0 48.7 38.7 52.8 36.3 16.0 39.4 54.4 20.2 40.2 47.8 65.5 41.4 32.6 38.2 17.6 2.3 15.3 64.3 53.5 28.2 28.8 49.2 73.1 36.6 10.1 41.3 25.5 61.2 77.6 2.9 42.3 30.2 84.5 166.2 22.5 62.6 72.3 1.4 10.6 32.9 24.6 23.9 23.6 9.7 19.5 55.0 45.4 29.0 0.9 27.3 47.5 148.9 37.9 165.7 92.4 23.4 23.0 42.5 30.6 2.5 182.2 292.7 11.2 177.7 9.4 16.8 8.4 10.7 264.3 12.9 7.4 14.5 431.8 28.4 202.6 22.9 7.3 92.3 32.4 44.5 13.9 57.7 58.3 8.0 19.2 12.2 19.4 0.9 17.1 30.0 3.1 3.2 20.5 24.2 23.9 11.9 33.3 28.2 23.9 51.6 25.1 19.7 6.2 35.8 30.8 25.8 8.4 25.4 10.2 78.6 45.0 32.4 38.8 37.3 13.5 3.2 37.8 30.5 219.1 56.3 53.5 24.0 45.9 39.7 132.2 35.2 3.6 11.4 49.8 1.7 118.5 50.8 28.5 59.6 152.9 28.3 14.3 80.0 30.2 54.4 121.7 14.9 10.3 53.3 70.7 50.9 57.9 13.2 28.6 28.7 47.9 55.7 39.0 6.4 13.1 13.8 25.2 50.4 53.8 23.6 10.4 95.0 19.3 10.3 52.8 33.2 PAK4 ENSG00000130669 "P21 (RAC1) activated kinase 4" O96013 19 39125770-39182816 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Apoptosis, Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "A549: 154.7;MCF7: 172.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025747, CAB044670, HPA070175, HPA072220" Uncertain Supported "Plasma membrane,Cell Junctions" NA Yes "Cluster 26: Non-specific - Mitochondria" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 17: Intestinal endocrine cells - Hormone signaling" "Plasma membrane, Cell Junctions" "CAB025747: , CAB044670: AB_1854940, HPA070175: AB_2686232, HPA072220: AB_2686497" "unprognostic (1.71e-1)" "unprognostic (2.84e-1)" "unprognostic (5.86e-2)" "unprognostic (2.84e-2)" "unprognostic (1.93e-1)" "unprognostic (8.51e-2)" "unprognostic (3.56e-3)" "unprognostic (1.13e-3)" "unprognostic (3.90e-2)" "unprognostic (4.04e-2)" "unprognostic (7.29e-2)" "prognostic unfavorable (9.85e-4)" "prognostic favorable (5.29e-5)" "unprognostic (2.39e-1)" "unprognostic (7.05e-2)" "unprognostic (2.02e-1)" "unprognostic (4.85e-2)" 11.6 20.0 16.7 8.1 18.2 5.3 22.1 14.2 18.4 27.2 14.0 30.2 27.4 20.6 9.4 43.9 23.4 7.5 15.5 13.9 13.4 37.2 26.2 39.6 4.5 17.1 17.2 24.2 31.8 16.2 30.5 16.3 15.8 40.7 8.0 5.8 42.4 11.0 14.0 40.4 25.1 5.7 12.0 13.8 25.3 35.0 15.7 5.4 29.3 4.3 5.4 20.2 30.4 17.0 62.8 154.7 22.7 34.8 7.1 7.5 68.1 29.3 11.7 19.3 19.4 102.1 51.9 14.3 43.3 18.7 25.2 22.7 12.6 23.2 7.2 38.0 35.4 16.9 27.5 50.4 11.3 17.5 23.6 9.0 10.2 18.1 12.9 12.6 25.5 21.4 34.3 11.0 11.8 172.7 18.6 18.9 41.4 55.2 36.7 18.5 17.9 10.9 19.0 67.9 72.2 49.9 29.8 130.6 33.6 11.7 58.1 28.4 42.8 32.6 55.6 37.8 53.0 12.3 12.9 11.9 39.9 10.3 39.9 0.3 0.7 1.2 0.6 0.3 0.8 0.5 0.7 1.1 0.9 0.6 0.5 0.5 0.5 0.9 0.6 0.8 0.9 0.7 16.7 18.2 14.2 18.4 13.9 13.4 17.1 17.2 15.8 12.0 15.7 17.0 5.1 0.0 1.5 9.4 3.9 14.4 15.9 13.8 9.6 18.8 34.2 21.7 2.0 20.0 9.1 18.4 25.0 42.6 4.4 47.5 31.3 20.5 4.1 19.5 8.5 15.0 44.9 5.0 3.9 19.7 67.4 8.8 23.9 23.3 5.7 21.6 10.0 13.3 9.6 21.9 4.2 33.8 28.5 5.3 4.1 6.4 11.8 3.6 7.2 8.4 11.2 13.6 8.2 9.5 13.5 21.8 44.2 10.5 5.8 21.7 39.5 14.4 13.7 13.4 0.0 8.5 7.5 10.4 24.0 20.1 18.8 65.4 6.0 22.3 33.9 24.3 PALM "KIAA0270, PALM1" ENSG00000099864 Paralemmin O75781 19 708935-748329 "Predicted intracellular proteins" "Cell shape" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 257.8" "Cell type enhanced" "Detected in many" "Astrocytes: 85.2;Distal tubular cells: 52.8;Hepatic stellate cells: 63.1;Leydig cells: 48.4;Muller glia cells: 92.8;Proximal tubular cells: 57.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 5 "non-classical monocyte: 1.9" "Lineage enriched" "Detected in single" 19 "monocytes: 1.9" "Cell line enhanced" "Detected in many" "AN3-CA: 16.6;EFO-21: 20.7;REH: 34.3;SH-SY5Y: 28.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041713, HPA049578" Approved Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 50: Fibroblasts - ECM organization" "Nucleoplasm, Plasma membrane" "HPA041713: AB_10794305, HPA049578: AB_2680822" "unprognostic (9.08e-3)" "unprognostic (2.97e-2)" "unprognostic (2.11e-2)" "unprognostic (3.53e-3)" "unprognostic (1.61e-1)" "unprognostic (3.77e-2)" "unprognostic (1.42e-1)" "unprognostic (8.39e-2)" "unprognostic (7.62e-2)" "unprognostic (1.36e-2)" "prognostic favorable (9.81e-4)" "unprognostic (2.74e-2)" "prognostic favorable (5.44e-4)" "unprognostic (1.24e-2)" "unprognostic (1.13e-1)" "unprognostic (1.55e-2)" "unprognostic (6.00e-2)" 89.0 23.1 158.4 2.0 140.7 0.7 66.0 86.1 257.8 60.3 54.5 54.4 7.4 43.3 3.3 14.4 47.0 2.8 41.1 165.1 97.0 52.7 7.3 30.0 0.6 106.4 103.6 65.7 5.8 1.2 62.5 6.6 96.9 42.6 0.6 4.6 12.9 8.3 9.6 33.4 20.8 2.4 95.0 23.4 18.0 19.6 112.1 0.6 21.0 1.7 0.2 29.4 41.8 110.5 0.0 7.6 14.6 16.6 0.6 0.2 2.2 0.9 0.0 1.0 0.2 1.9 0.1 0.0 20.7 0.0 0.0 2.7 8.0 0.0 0.4 0.0 14.1 0.0 4.3 9.3 9.4 0.0 0.3 3.0 0.0 0.9 0.0 0.4 0.4 1.6 4.6 0.1 1.1 15.9 1.1 9.4 5.9 1.0 3.2 34.3 0.0 0.2 0.6 0.0 1.7 28.0 7.5 0.1 0.2 4.6 1.8 4.5 0.0 0.0 13.4 16.1 0.0 0.0 0.0 0.1 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.0 158.4 140.7 86.1 257.8 165.1 97.0 106.4 103.6 96.9 95.0 112.1 110.5 27.2 0.0 1.7 85.2 2.7 7.1 7.2 6.3 1.8 11.4 5.7 5.3 5.8 1.5 4.9 5.5 12.5 0.9 0.2 1.3 52.8 1.4 1.4 3.8 27.0 25.6 0.0 1.3 26.9 0.2 7.2 37.6 1.1 5.9 0.0 1.4 63.1 0.4 1.0 25.2 15.1 0.1 12.2 2.4 5.4 6.6 48.4 1.1 17.8 10.3 0.1 92.8 0.0 16.6 9.8 0.2 1.4 45.1 0.1 10.1 7.2 57.9 0.5 5.7 0.0 2.3 14.1 0.8 7.3 1.1 7.0 1.9 1.1 0.1 0.4 7.2 PAQR8 "C6orf33, LMPB1, MPRB" ENSG00000170915 "Progestin and adipoQ receptor family member 8" Q8TEZ7 6 52361421-52407777 "Predicted membrane proteins, Transporters" "Differentiation, Oogenesis" "Developmental protein, Receptor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 144.9" "Cell type enhanced" "Detected in many" "Astrocytes: 168.5;Distal enterocytes: 154.3;Microglial cells: 74.0;Oligodendrocytes: 298.2;Paneth cells: 80.7;Proximal enterocytes: 100.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Hep G2: 41.8;OE19: 87.9;SuSa: 34.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA064625 Supported "Golgi apparatus,Plasma membrane" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" "Golgi apparatus" "HPA064625: AB_2685304" "prognostic favorable (4.61e-4)" "unprognostic (7.39e-3)" "unprognostic (2.77e-3)" "unprognostic (8.23e-2)" "unprognostic (4.33e-1)" "unprognostic (4.08e-3)" "unprognostic (2.66e-2)" "unprognostic (5.67e-2)" "unprognostic (6.37e-2)" "unprognostic (4.30e-3)" "unprognostic (2.10e-1)" "unprognostic (5.55e-2)" "unprognostic (8.82e-3)" "unprognostic (1.04e-1)" "unprognostic (2.12e-1)" "unprognostic (3.14e-2)" "prognostic favorable (6.40e-4)" 2.7 4.0 83.7 9.2 113.9 1.2 2.3 122.9 86.7 4.7 42.0 38.9 19.3 5.1 8.0 17.6 6.3 6.0 3.5 74.4 89.7 8.0 1.5 7.3 10.3 133.8 110.7 24.3 2.8 5.2 2.2 7.0 123.1 4.3 36.7 2.9 2.2 23.3 0.9 3.1 33.7 6.3 102.8 6.2 32.3 3.7 106.4 9.2 2.8 1.5 7.6 9.7 5.5 144.9 0.9 1.0 10.7 4.6 6.3 10.2 7.3 3.2 12.1 2.0 4.4 4.1 3.8 1.1 1.2 2.2 4.7 0.4 1.4 5.3 3.2 14.8 1.7 6.6 1.0 41.8 1.7 1.8 0.9 2.9 0.7 1.4 7.5 7.4 11.5 12.9 1.5 6.4 8.3 1.5 4.4 6.1 5.4 87.9 0.5 11.5 1.7 2.8 12.4 3.1 4.0 8.7 0.8 0.3 12.4 34.4 0.3 14.7 4.8 4.0 1.6 1.2 1.9 1.9 2.6 1.6 3.7 16.9 21.5 3.0 3.2 1.4 2.8 0.6 4.2 1.1 8.3 5.7 7.0 1.0 17.8 8.3 0.6 8.5 0.6 3.5 6.2 4.2 83.7 113.9 122.9 86.7 74.4 89.7 133.8 110.7 123.1 102.8 106.4 144.9 4.9 3.2 10.6 168.5 3.6 2.0 3.7 3.1 0.6 2.1 0.7 1.3 4.4 14.3 3.5 3.7 8.4 1.7 7.6 154.3 0.0 4.4 0.5 12.2 3.9 7.4 22.9 4.2 21.1 1.1 3.1 6.8 18.8 7.5 4.5 23.7 4.2 0.2 8.8 0.0 19.4 45.5 6.1 19.8 3.5 1.6 5.6 7.3 14.2 74.0 11.4 4.2 3.1 19.1 298.2 4.9 80.7 10.1 0.6 6.6 100.5 0.1 8.9 3.3 0.0 1.0 3.6 12.1 3.3 5.3 1.0 0.8 9.2 10.0 42.5 7.3 PARD3 "ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118" ENSG00000148498 "Par-3 family cell polarity regulator" Q8TEW0 10 34109560-34815325 "Disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Differentiation" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Astrocytes: 455.4;Inhibitory neurons: 147.0;Microglial cells: 193.0;Oligodendrocyte precursor cells: 367.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 50 "basophil: 9.6" "Lineage enriched" "Detected in single" 97 "granulocytes: 9.6" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA030443 Approved Supported "Plasma membrane,Cell Junctions" NA NA 21000 "Cluster 34: Basophils - Unknown function" "Cluster 31: Skin - Epidermis development" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cell Junctions" "HPA030443: AB_10600926" "unprognostic (9.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.62e-1)" "unprognostic (2.83e-2)" "unprognostic (1.81e-2)" "unprognostic (3.52e-2)" "prognostic unfavorable (1.73e-5)" "unprognostic (3.48e-1)" "unprognostic (3.49e-1)" "unprognostic (8.07e-2)" "unprognostic (5.82e-3)" "unprognostic (1.28e-1)" "unprognostic (1.05e-1)" "unprognostic (1.20e-2)" "unprognostic (3.54e-1)" "unprognostic (9.20e-2)" "prognostic unfavorable (4.41e-4)" 13.1 15.9 19.6 4.8 17.0 0.5 21.5 10.9 12.4 25.9 16.0 30.4 10.6 20.7 12.2 47.8 20.6 14.9 14.6 17.8 20.6 25.1 22.1 15.2 2.6 15.7 22.1 38.5 34.2 20.7 7.3 21.7 15.9 17.0 21.7 13.6 20.1 23.9 40.5 52.1 13.4 21.8 16.0 4.2 17.7 14.0 24.0 13.5 15.2 30.9 12.4 21.3 30.8 13.9 50.6 121.1 40.1 28.6 28.5 24.2 59.1 22.2 25.4 37.3 40.0 44.3 43.3 0.3 31.4 44.6 30.4 35.8 34.7 56.7 46.1 0.4 26.8 0.0 14.9 44.1 36.2 5.7 0.1 28.7 54.9 50.9 38.1 35.9 23.3 32.4 34.7 14.9 44.8 35.4 59.3 4.2 18.0 32.7 41.4 44.9 39.0 21.9 80.9 38.4 20.1 20.9 26.8 37.3 42.9 49.6 21.1 6.7 28.4 18.7 56.1 35.5 24.2 13.2 17.1 0.1 21.0 0.2 22.3 9.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.2 19.6 17.0 10.9 12.4 17.8 20.6 15.7 22.1 15.9 16.0 24.0 13.9 6.4 35.3 35.3 455.4 0.2 34.0 42.3 19.8 19.9 8.7 17.1 24.9 39.0 21.5 24.3 14.7 29.2 24.9 0.2 25.6 0.0 34.1 19.9 22.3 29.9 9.4 24.0 2.7 5.4 36.4 25.0 22.3 13.3 33.4 1.3 33.1 8.9 24.8 3.4 11.8 147.0 30.1 14.2 0.6 4.7 20.3 30.4 7.7 5.4 193.0 0.8 28.8 1.0 367.9 13.9 38.8 23.8 38.4 1.4 31.4 13.7 25.6 29.3 19.7 26.3 23.4 26.1 6.2 27.6 40.4 61.5 40.1 1.5 32.1 22.0 47.2 PAWR "par-4, PAR4" ENSG00000177425 "Pro-apoptotic WT1 regulator" Q96IZ0 12 79574979-79690964 "Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Prostatic glandular cells: 273.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "memory B-cell: 2.7;naive B-cell: 2.8;NK-cell: 1.4" "Group enriched" "Detected in many" 5 "B-cells: 2.8;NK-cells: 1.4" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA012640, CAB020779" Approved Approved "Plasma membrane,Actin filaments" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Actin filaments" "CAB020779: , HPA012640: AB_1855748" "unprognostic (2.42e-1)" "unprognostic (5.58e-2)" "unprognostic (9.77e-3)" "unprognostic (5.39e-2)" "unprognostic (9.44e-3)" "unprognostic (4.21e-3)" "unprognostic (9.21e-2)" "unprognostic (1.37e-1)" "unprognostic (4.78e-1)" "unprognostic (3.03e-1)" "unprognostic (2.42e-3)" "unprognostic (4.97e-3)" "unprognostic (2.22e-2)" "unprognostic (2.58e-2)" "unprognostic (4.64e-1)" "unprognostic (2.22e-1)" "unprognostic (4.23e-2)" 11.0 6.1 6.8 9.0 8.0 3.1 13.4 4.8 3.6 20.9 21.6 16.7 11.7 28.0 15.9 14.3 24.7 8.5 5.2 4.7 7.6 12.6 13.3 11.6 6.9 7.7 13.4 20.4 11.6 13.3 8.7 6.2 5.5 14.9 15.3 0.7 14.3 21.8 1.7 16.5 12.1 16.7 5.5 6.2 13.6 10.9 12.4 4.3 16.2 1.8 6.6 16.1 16.4 5.5 54.5 49.1 8.8 0.3 4.4 1.9 58.6 34.1 9.9 17.0 10.3 61.5 20.2 36.2 61.2 19.0 12.2 59.2 31.0 25.7 24.3 14.7 42.2 0.0 28.7 27.1 23.6 0.5 1.0 4.1 53.4 13.4 76.0 63.0 28.7 14.8 2.1 4.9 18.8 41.0 8.8 0.2 42.6 15.7 27.7 0.0 20.2 23.5 32.4 40.4 25.4 0.1 60.8 31.8 5.7 29.4 28.5 0.3 43.2 25.4 22.8 0.9 23.1 15.3 21.6 26.8 4.2 0.1 11.2 0.4 0.0 0.0 0.0 0.0 0.0 2.7 0.1 0.1 0.2 2.8 0.2 0.2 0.2 1.4 0.0 0.1 0.0 0.0 6.8 8.0 4.8 3.6 4.7 7.6 7.7 13.4 5.5 5.5 12.4 5.5 51.3 80.1 40.7 16.6 33.1 200.1 170.3 42.0 63.2 6.4 93.6 77.3 21.0 60.1 59.2 66.2 0.0 57.1 4.6 103.9 17.6 57.3 62.6 75.7 50.9 31.0 68.8 4.6 1.5 38.5 81.4 41.7 32.1 157.5 1.3 87.4 13.6 54.5 6.5 16.8 50.9 120.9 32.6 1.6 19.2 96.3 84.8 5.3 17.8 23.4 0.4 2.5 4.1 30.7 0.9 83.2 72.0 91.0 11.4 273.4 44.3 47.2 49.9 1.4 85.5 18.3 109.7 98.4 62.1 76.6 179.6 76.9 6.7 62.9 92.7 169.5 PCDH7 "BH-Pcdh, PPP1R120" ENSG00000169851 "Protocadherin 7" O60245 4 30720415-31146805 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 50.1" "Group enriched" "Detected in many" 8 "Astrocytes: 311.8;Excitatory neurons: 1152.0;Inhibitory neurons: 882.3;Oligodendrocyte precursor cells: 917.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HEK 293: 43.4;RH-30: 120.4;RT4: 65.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA011866, HPA046521" Uncertain Enhanced "Plasma membrane,Cell Junctions" NA NA 340000 "Cluster 10: Brain - Neuronal signaling" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cell Junctions" "HPA011866: AB_1855047, HPA046521: AB_2679682" "unprognostic (1.87e-1)" "unprognostic (8.88e-2)" "unprognostic (4.48e-2)" "unprognostic (3.32e-1)" "unprognostic (1.38e-1)" "unprognostic (2.45e-1)" "unprognostic (1.04e-2)" "prognostic unfavorable (6.46e-5)" "unprognostic (1.96e-1)" "unprognostic (8.39e-2)" "unprognostic (1.02e-2)" "unprognostic (9.91e-2)" "unprognostic (2.09e-4)" "prognostic unfavorable (6.42e-4)" "unprognostic (1.55e-1)" "unprognostic (7.65e-2)" "unprognostic (1.56e-2)" 1.8 3.2 10.5 5.2 14.6 0.0 3.0 0.0 33.7 23.9 0.0 19.2 3.2 16.9 25.1 14.3 9.7 8.1 19.1 23.7 50.1 2.0 1.0 2.9 1.4 13.0 14.3 4.7 0.9 1.1 0.2 0.2 14.3 10.6 7.8 3.4 0.8 18.2 0.6 11.6 5.0 22.1 3.9 18.6 11.4 1.0 46.3 1.4 4.1 0.4 1.2 16.3 5.9 11.8 0.0 1.1 14.4 20.1 29.5 28.5 0.0 3.8 0.0 1.9 0.9 1.9 26.5 0.0 0.1 0.2 0.0 15.3 1.3 38.5 3.4 0.0 43.4 0.1 26.8 0.0 30.4 0.6 0.0 17.2 8.8 1.0 10.7 17.5 7.5 0.0 0.0 0.0 9.0 0.1 0.0 0.1 8.8 9.3 4.0 0.0 120.4 0.0 0.9 65.2 0.9 0.2 0.4 1.2 1.3 8.2 1.8 6.9 0.0 24.1 6.2 6.7 0.0 0.0 0.0 0.0 18.8 0.1 18.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.5 14.6 0.0 33.7 23.7 50.1 13.0 14.3 14.3 3.9 46.3 11.8 1.1 0.0 0.0 311.8 0.3 85.0 92.4 25.7 46.7 46.8 0.7 9.0 83.2 0.0 13.7 64.4 0.0 0.1 0.0 0.3 0.0 0.6 16.9 66.8 8.4 7.6 0.0 0.0 1152.0 0.7 0.1 24.0 20.9 60.4 1.3 0.8 19.2 0.1 0.3 10.1 882.3 0.5 4.1 1.0 3.5 10.4 0.3 1.3 21.4 43.1 0.0 1.3 0.0 917.3 26.4 26.5 0.0 28.6 1.3 26.1 0.0 0.2 27.0 3.4 0.0 51.3 11.0 1.1 2.7 18.5 38.6 0.1 1.8 1.7 0.3 50.3 PCDHA12 PCDH-ALPHA12 ENSG00000251664 "Protocadherin alpha 12" Q9UN75 5 140875302-141012347 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 3.9" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 28.9;Alveolar cells type 2: 5.1;Bipolar cells: 11.4;Cone photoreceptor cells: 6.2;Horizontal cells: 5.0" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "cerebellum: 3.9;cerebral cortex: 1.1" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 7.1;hTCEpi: 3.4;PC-3: 5.1;RT4: 5.2;SH-SY5Y: 2.1" HPA035812 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 21: Non-specific - Transcription" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA035812: AB_2674796" "unprognostic (3.95e-2)" "unprognostic (7.74e-2)" "unprognostic (7.55e-2)" "unprognostic (3.87e-2)" "unprognostic (2.74e-2)" "unprognostic (2.24e-2)" "unprognostic (2.08e-2)" "unprognostic (4.29e-2)" "unprognostic (1.07e-2)" "unprognostic (1.98e-4)" "unprognostic (3.18e-4)" "unprognostic (1.11e-1)" "unprognostic (3.21e-3)" "unprognostic (6.97e-2)" 0.3 0.3 0.4 0.0 0.5 0.0 0.2 3.9 1.1 0.8 0.0 0.1 0.0 0.2 0.1 0.0 0.4 0.7 0.0 0.3 0.1 0.6 0.1 1.5 0.0 0.3 0.1 0.0 0.7 0.0 0.8 0.0 0.4 0.0 0.0 0.7 0.6 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.5 0.0 7.1 1.1 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 3.4 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.6 0.0 0.0 1.6 1.7 5.1 0.0 0.0 0.0 0.1 5.2 0.2 2.1 0.0 0.6 0.0 0.3 1.2 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.5 3.9 1.1 0.3 0.1 0.3 0.1 0.4 0.1 0.0 0.5 0.2 28.9 5.1 0.0 0.0 0.0 0.0 0.8 0.0 11.4 0.8 1.3 0.4 4.3 1.9 1.8 6.2 0.0 0.0 0.1 0.0 0.7 1.3 0.8 0.3 0.3 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.8 0.0 0.1 1.4 0.1 0.0 5.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 1.0 0.0 0.4 0.0 0.1 0.0 0.2 1.3 3.6 0.0 0.2 0.3 0.9 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PCDHB1 PCDH-BETA1 ENSG00000171815 "Protocadherin beta 1" Q9Y5F3 5 141051374-141059346 "Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in single" "skeletal muscle: 1.4" "Cell type enhanced" "Detected in some" "Alveolar cells type 2: 1.1;Cardiomyocytes: 2.7;Respiratory ciliated cells: 2.2;Skeletal myocytes: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in single" HPA053921 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA053921: AB_2682310" "unprognostic (5.54e-2)" "unprognostic (1.60e-2)" "unprognostic (9.01e-4)" "unprognostic (8.65e-2)" "unprognostic (8.00e-2)" "unprognostic (7.82e-2)" "unprognostic (2.63e-2)" "unprognostic (1.40e-1)" "unprognostic (8.17e-5)" "unprognostic (3.38e-2)" "unprognostic (9.40e-2)" "unprognostic (1.23e-1)" "unprognostic (5.77e-4)" 0.1 0.2 0.4 0.1 0.4 0.4 0.0 0.9 0.5 0.0 0.1 0.1 0.2 0.1 0.3 0.1 0.4 0.1 0.1 0.4 0.2 0.3 0.1 0.1 0.2 0.4 0.3 0.1 0.4 0.3 0.5 0.1 0.4 0.1 0.0 0.5 0.2 0.0 1.4 0.3 0.2 0.0 0.1 0.2 0.3 0.3 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.3 0.2 0.2 0.3 0.0 0.2 0.3 0.0 0.0 0.0 0.1 0.2 0.2 0.4 0.1 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.2 0.1 0.5 0.0 0.2 0.1 0.1 0.2 0.2 0.0 0.2 0.2 0.1 0.0 0.2 0.4 0.1 0.0 0.3 0.2 0.2 0.1 0.0 0.2 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.2 0.2 0.2 0.5 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.4 0.1 0.1 0.1 0.0 0.0 0.4 0.4 0.9 0.5 0.4 0.2 0.4 0.3 0.4 0.1 0.3 0.4 0.0 0.0 1.1 0.0 0.4 0.0 0.9 0.0 0.0 0.3 0.1 0.0 2.7 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 2.2 0.4 0.0 1.2 0.2 0.2 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.7 PCDHB16 "KIAA1621, ME1, PCDH-BETA16, PCDH3X, PCDHB8a" ENSG00000272674 "Protocadherin beta 16" Q9NRJ7 5 141182387-141186226 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Bipolar cells: 14.9;Endometrial stromal cells: 10.0;Fibroblasts: 7.3;Horizontal cells: 8.4;Skeletal myocytes: 7.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 19.4;LHCN-M2: 10.5;U-138 MG: 39.3;U-2197: 11.1;U-87 MG: 9.9" "Low region specificity" "Detected in all" HPA014668 Approved "Vesicles,Plasma membrane" NA NA "Cluster 89: Fibroblasts - ECM organization" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "HPA014668: AB_1855055" "unprognostic (3.44e-3)" "unprognostic (4.03e-2)" "unprognostic (8.14e-2)" "unprognostic (8.60e-2)" "unprognostic (2.78e-2)" "unprognostic (1.36e-2)" "unprognostic (1.17e-1)" "unprognostic (4.03e-2)" "unprognostic (3.13e-2)" "unprognostic (7.55e-3)" "unprognostic (3.49e-2)" "unprognostic (9.57e-2)" "unprognostic (3.55e-2)" "unprognostic (7.49e-3)" "unprognostic (2.00e-2)" "unprognostic (7.92e-3)" "unprognostic (2.83e-3)" 3.1 1.9 1.2 1.2 0.9 0.2 2.4 2.1 1.8 2.6 0.0 1.6 0.5 4.5 4.8 0.7 2.2 2.0 2.5 1.6 0.8 2.0 1.0 2.4 0.6 2.0 1.0 6.7 1.9 4.3 2.3 1.2 1.2 1.7 0.9 2.2 1.8 0.9 1.0 1.3 0.9 2.7 1.5 1.1 0.9 1.4 1.3 0.4 1.7 3.3 0.2 1.6 1.5 2.2 0.1 0.3 1.0 19.4 7.8 5.2 0.6 0.8 3.8 0.0 0.3 0.1 0.3 0.0 5.0 0.9 2.1 0.2 0.7 0.0 0.0 0.1 0.0 0.0 0.4 0.4 0.0 0.1 0.2 0.1 0.1 0.0 0.0 3.3 0.1 0.2 0.1 2.0 10.5 0.4 0.0 0.1 1.5 0.0 0.2 0.1 2.8 0.0 0.6 0.2 0.7 2.6 0.3 0.6 3.9 0.5 7.9 0.0 0.6 39.3 1.7 11.1 2.7 0.1 0.1 0.0 9.9 0.1 5.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 1.2 0.9 2.1 1.8 1.6 0.8 2.0 1.0 1.2 1.5 1.3 2.2 6.4 3.2 1.5 0.0 0.0 0.8 0.1 1.0 0.0 14.9 1.2 2.4 1.9 5.7 0.6 1.8 0.0 0.0 0.0 0.0 1.9 0.8 1.2 0.6 10.0 4.8 1.8 0.0 0.0 4.7 0.0 7.3 0.5 0.4 0.0 0.2 2.2 0.1 0.1 8.4 0.0 0.0 4.1 0.3 0.9 1.5 4.7 0.2 0.0 0.0 0.0 5.4 0.0 0.0 0.0 1.7 0.0 5.7 0.1 0.1 0.0 0.7 0.2 1.6 0.0 7.6 5.9 2.9 0.3 0.5 1.4 0.0 0.2 0.4 0.0 0.0 PCDHB5 "DKFZp586B0217, PCDH-BETA5" ENSG00000113209 "Protocadherin beta 5" Q9Y5E4 5 141135206-141138615 "Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Bipolar cells: 5.2;Early spermatids: 8.2;Muller glia cells: 5.0;Spermatocytes: 13.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 18.7;GAMG: 13.9;NTERA-2: 17.7;RH-30: 14.0;SCLC-21H: 16.4;SuSa: 21.7;T-47d: 17.6;U-138 MG: 32.4;U-2 OS: 14.1;WM-115: 14.7" "Low region specificity" "Detected in many" "HPA013191, HPA067473" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 12: NES - Nervous system development" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Vesicles "HPA013191: AB_1855059, HPA067473: " "unprognostic (2.21e-1)" "unprognostic (4.71e-2)" "unprognostic (4.05e-3)" "unprognostic (1.81e-1)" "unprognostic (2.84e-2)" "unprognostic (5.23e-2)" "unprognostic (2.27e-2)" "unprognostic (1.76e-1)" "unprognostic (9.41e-2)" "unprognostic (1.25e-1)" "unprognostic (1.32e-2)" "unprognostic (3.16e-1)" "unprognostic (1.32e-1)" "unprognostic (1.06e-3)" "unprognostic (6.65e-2)" "unprognostic (3.14e-2)" "unprognostic (1.55e-3)" 1.4 1.6 2.2 0.4 1.7 0.0 1.6 1.1 3.2 3.4 0.0 1.4 0.2 4.2 3.5 0.7 2.8 1.8 1.9 2.8 0.6 2.4 0.7 1.7 0.2 2.5 1.6 5.9 4.7 2.7 3.2 0.4 1.3 2.9 0.3 2.4 2.2 2.1 1.1 0.6 0.6 2.1 1.7 0.7 1.0 3.1 1.8 0.4 2.5 0.6 0.1 1.6 1.3 2.3 0.0 1.0 18.7 0.3 1.3 0.8 0.2 0.4 0.1 0.3 0.3 0.0 0.0 0.0 9.6 0.0 13.9 0.0 9.8 0.0 0.2 0.0 0.3 0.0 0.0 0.0 0.3 0.0 1.0 0.7 0.0 0.0 0.1 3.8 0.9 0.0 0.7 0.1 0.0 0.0 0.1 0.0 17.7 0.0 0.0 0.0 14.0 0.0 0.0 0.0 16.4 0.5 0.0 0.2 6.1 21.7 17.6 4.3 0.0 32.4 14.1 5.3 0.0 0.0 0.0 0.0 1.7 0.0 14.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 1.7 1.1 3.2 2.8 0.6 2.5 1.6 1.3 1.7 1.8 2.3 1.9 0.0 0.0 0.0 0.0 0.0 1.5 0.8 0.6 5.2 0.9 2.2 1.1 1.5 1.8 1.8 0.0 0.0 0.0 0.0 0.0 2.5 8.2 0.5 4.3 1.1 0.0 0.0 0.0 3.6 0.0 1.5 0.0 0.2 0.0 0.5 0.4 0.4 0.0 3.3 0.0 0.0 0.0 0.0 0.0 3.8 3.1 0.1 0.0 0.0 0.0 5.0 0.0 0.0 0.0 2.2 0.0 4.5 0.0 1.1 0.0 0.5 0.1 0.7 0.0 2.1 2.7 13.0 0.0 0.2 0.1 0.0 0.0 0.3 0.0 0.6 PCLO "ACZ, DKFZp779G1236, KIAA0559" ENSG00000186472 "Piccolo presynaptic cytomatrix protein" Q9Y6V0 7 82754012-83162930 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Neurodegeneration "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 25.6;pituitary gland: 11.1;retina: 21.7" "Group enriched" "Detected in many" 5 "Excitatory neurons: 655.4;Inhibitory neurons: 746.4" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebellum: 25.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 28 "REH: 263.3;U-2 OS: 284.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015858, HPA029579, CAB079012" Approved Supported Approved "Nuclear speckles,Plasma membrane" NA NA 6000000 "Cluster 58: Brain - Synaptic function" "Cluster 14: REH - Unknown function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles, Plasma membrane" "CAB079012: , HPA015858: AB_1855071, HPA029579: AB_10602044" "unprognostic (1.32e-2)" "unprognostic (1.99e-1)" "unprognostic (9.33e-2)" "unprognostic (1.31e-1)" "unprognostic (2.08e-2)" "unprognostic (1.52e-1)" "unprognostic (4.49e-3)" "unprognostic (6.14e-2)" "unprognostic (4.61e-2)" "unprognostic (1.82e-1)" "unprognostic (3.00e-1)" "unprognostic (1.56e-1)" "unprognostic (4.79e-6)" "unprognostic (5.15e-2)" "unprognostic (2.42e-2)" "unprognostic (1.36e-5)" "unprognostic (6.62e-5)" 1.8 4.2 4.0 0.2 5.5 0.0 2.4 25.6 22.4 1.5 0.0 2.1 1.5 0.3 3.8 2.3 1.0 0.9 1.4 7.8 1.7 4.4 0.1 0.8 0.1 0.0 0.0 0.8 3.9 4.4 11.1 0.3 0.0 2.5 1.7 21.7 2.5 2.5 0.1 2.0 1.7 0.1 0.0 0.5 1.5 3.7 1.3 1.2 4.6 0.1 0.2 0.6 2.6 4.2 1.2 1.6 1.9 0.0 0.8 0.1 0.0 0.7 0.7 0.5 1.0 0.3 0.7 0.0 0.0 0.8 7.7 0.6 5.7 2.4 2.4 0.3 0.8 0.0 1.2 0.1 0.0 0.8 0.2 0.4 1.8 0.0 9.6 0.5 0.0 0.1 0.0 0.0 0.8 0.8 0.2 0.0 2.0 1.0 4.7 263.3 4.2 0.0 1.9 0.9 4.9 3.4 0.2 2.7 0.6 1.2 3.4 0.6 0.0 0.0 284.5 1.2 0.6 0.2 0.0 0.5 1.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.0 5.5 25.6 22.4 7.8 1.7 0.0 0.0 0.0 0.0 1.3 4.2 0.6 9.6 17.9 40.5 0.0 2.5 9.0 3.2 13.6 121.9 11.0 9.7 31.2 22.8 12.6 1.8 131.3 1.9 0.0 22.9 7.9 6.4 13.0 7.4 6.7 2.5 60.1 0.0 655.4 4.9 0.4 2.4 20.4 13.5 0.0 24.2 0.0 0.2 1.7 85.8 746.4 15.0 2.0 0.0 0.0 7.9 2.8 0.4 0.0 50.6 0.0 16.2 0.0 73.9 73.7 2.5 21.9 6.4 0.0 3.9 13.5 23.0 7.7 86.9 0.0 0.3 3.2 5.0 19.5 19.3 3.4 0.7 0.3 37.5 9.3 6.0 PCMTD1 FLJ10883 ENSG00000168300 "Protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1" Q96MG8 8 51817575-51899186 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025696, HPA061444" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 8: Non-specific - Mitochondria" "Cluster 2: Karpas-707 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Nucleoplasm "HPA025696: AB_1855077, HPA061444: AB_2684519" "unprognostic (3.16e-2)" "unprognostic (1.24e-1)" "unprognostic (1.47e-1)" "unprognostic (2.79e-1)" "unprognostic (1.41e-1)" "unprognostic (6.73e-3)" "unprognostic (2.58e-2)" "unprognostic (2.53e-1)" "unprognostic (1.05e-1)" "unprognostic (1.66e-1)" "unprognostic (2.18e-2)" "unprognostic (8.38e-2)" "unprognostic (3.73e-1)" "unprognostic (2.48e-2)" "unprognostic (1.13e-1)" "unprognostic (3.11e-3)" "unprognostic (3.11e-3)" 36.5 35.2 18.2 23.3 20.2 16.8 38.2 25.2 21.9 33.8 23.2 38.8 25.9 35.3 47.5 28.0 30.8 29.0 35.5 16.4 19.9 38.3 30.4 28.3 28.8 19.1 19.2 42.6 73.9 77.9 25.5 26.3 19.9 36.1 25.8 25.4 57.6 32.0 83.4 33.5 26.8 28.3 18.9 46.3 29.5 14.9 18.9 35.1 53.3 67.1 27.3 32.6 31.0 21.6 11.7 5.7 24.3 5.4 34.1 28.4 14.0 13.4 22.8 5.5 9.0 3.1 23.6 12.0 18.0 17.3 8.4 27.2 4.7 15.8 9.3 11.9 8.5 12.6 11.7 8.3 43.9 5.2 12.4 30.4 31.7 6.9 17.4 35.8 24.4 16.0 9.5 36.0 12.0 4.2 24.5 13.7 8.9 16.7 3.0 8.0 4.5 13.8 24.7 21.7 16.2 15.0 10.9 14.8 17.1 18.5 14.2 7.6 22.2 6.8 5.9 8.8 5.2 21.6 15.6 3.9 16.4 11.4 7.0 18.7 8.4 23.2 8.6 11.0 10.4 13.1 11.5 9.4 8.1 13.0 13.5 12.4 29.4 21.6 12.7 14.7 13.2 9.1 18.2 20.2 25.2 21.9 16.4 19.9 19.1 19.2 19.9 18.9 18.9 21.6 98.4 115.4 68.1 78.7 78.1 54.0 66.0 49.7 58.6 80.7 66.7 61.0 92.7 48.6 52.0 84.6 10.4 38.1 80.7 28.7 64.6 32.9 4.7 66.6 63.9 79.3 46.7 51.4 144.7 39.8 37.2 79.2 45.9 92.2 53.0 107.2 76.4 37.1 25.1 58.9 159.7 39.0 61.1 51.8 56.8 10.4 104.1 62.7 71.2 144.3 52.5 120.8 55.6 106.1 122.3 43.8 32.2 120.0 101.8 98.0 45.5 92.8 56.7 24.0 39.5 73.2 68.2 16.4 24.2 38.3 59.2 68.5 62.1 87.6 30.9 94.6 PDAP1 "HASPP28, PAP, PAP1" ENSG00000106244 "PDGFA associated protein 1" Q13442 7 99392048-99408597 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB021103, HPA050294, HPA060836" Approved Enhanced "Plasma membrane,Cytosol" NA NA 410000 "Cluster 33: Neutrophils - Chromatin organization" "Cluster 80: Striated muscle - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB021103: AB_10057973, HPA050294: AB_2681077, HPA060836: AB_2684374" "unprognostic (2.27e-1)" "unprognostic (1.45e-1)" "unprognostic (3.87e-2)" "unprognostic (1.49e-1)" "unprognostic (1.41e-2)" "unprognostic (4.01e-3)" "prognostic unfavorable (6.67e-4)" "unprognostic (5.77e-2)" "unprognostic (3.50e-1)" "unprognostic (2.65e-2)" "unprognostic (2.63e-1)" "unprognostic (3.35e-2)" "unprognostic (1.45e-2)" "unprognostic (3.51e-2)" "unprognostic (1.79e-1)" "unprognostic (3.49e-1)" "unprognostic (2.97e-2)" 25.7 29.6 35.8 22.6 36.2 23.2 24.4 36.5 39.3 26.2 34.1 32.4 17.9 26.9 17.5 37.2 22.6 11.9 40.2 34.4 36.1 28.5 31.3 24.0 18.9 37.3 37.9 25.7 26.6 22.5 21.9 19.2 37.4 26.0 18.0 22.9 26.2 20.9 105.0 27.9 23.3 21.1 37.6 23.8 26.3 19.7 37.0 25.5 24.3 59.7 22.4 29.3 26.4 36.6 96.9 82.4 54.6 71.0 41.5 43.2 34.7 76.7 44.9 61.6 51.8 83.9 47.4 41.3 67.2 74.7 78.4 50.2 66.3 78.4 60.5 59.8 74.4 43.6 80.8 74.1 60.8 80.1 40.5 45.6 58.5 68.1 110.3 56.3 62.7 67.5 103.0 75.6 61.4 200.3 110.4 111.2 68.7 98.1 88.3 50.5 54.3 73.6 63.6 73.0 54.8 110.6 58.0 92.4 43.4 61.3 41.1 42.5 57.6 83.6 91.4 100.8 123.6 71.4 87.5 91.0 67.7 72.2 89.1 13.4 12.1 12.5 15.4 16.6 13.9 15.7 14.2 11.2 10.2 14.9 9.8 13.2 31.6 28.0 15.6 21.1 20.9 6.6 35.8 36.2 36.5 39.3 34.4 36.1 37.3 37.9 37.4 37.6 37.0 36.6 82.9 86.6 94.7 6.2 73.6 62.2 110.6 104.6 57.5 97.4 84.3 76.6 63.6 72.9 86.7 42.3 33.3 213.1 84.7 101.6 168.3 176.1 60.3 91.3 118.6 99.1 117.9 151.7 10.1 171.0 223.0 87.4 59.7 88.3 72.2 83.4 61.8 80.8 114.9 77.4 11.6 116.5 75.3 38.3 63.3 78.3 83.6 66.1 103.2 5.6 102.1 166.4 119.4 8.0 17.4 177.4 92.2 92.2 102.5 184.3 100.0 134.5 96.8 101.0 52.6 85.6 127.2 132.5 123.0 131.9 65.6 184.4 79.5 115.2 114.0 122.5 PDCD7 "ES18, HES18" ENSG00000090470 "Programmed cell death 7" Q8N8D1 15 65117379-65133808 "Predicted intracellular proteins" Apoptosis "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Bipolar cells: 176.1;Cone photoreceptor cells: 221.0;Rod photoreceptor cells: 176.3;Spermatocytes: 164.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049388 Approved Approved "Nucleoli,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 21: Non-specific - Transcription" "Cluster 16: U-266 - Nucleosome" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoli "HPA049388: AB_2680741" "unprognostic (7.71e-3)" "unprognostic (3.25e-1)" "unprognostic (4.09e-1)" "unprognostic (1.52e-1)" "unprognostic (1.54e-1)" "unprognostic (1.22e-1)" "unprognostic (6.68e-3)" "unprognostic (2.36e-2)" "unprognostic (3.18e-3)" "unprognostic (8.18e-2)" "unprognostic (3.28e-2)" "unprognostic (5.36e-2)" "prognostic unfavorable (1.00e-4)" "unprognostic (5.29e-2)" "unprognostic (3.42e-2)" "unprognostic (1.44e-1)" "unprognostic (1.62e-2)" 12.0 12.4 13.8 11.9 14.3 10.0 11.9 18.0 18.2 16.2 12.2 15.8 9.9 16.5 12.7 17.8 13.6 8.4 11.4 14.2 13.3 10.3 12.5 10.2 14.5 14.2 13.5 16.8 11.2 11.6 10.9 11.9 14.6 13.0 9.3 10.8 10.0 11.9 13.1 11.1 11.3 13.3 12.0 13.4 11.0 18.9 14.2 15.7 12.5 8.7 15.1 14.8 14.0 16.7 18.2 14.9 24.8 25.7 24.4 34.2 15.0 20.4 22.6 24.7 18.8 18.2 19.7 34.9 21.7 16.5 18.5 33.5 63.9 14.7 17.7 21.3 17.0 33.9 12.8 15.9 22.5 46.6 21.8 20.0 22.0 13.6 25.4 23.7 19.8 25.6 44.0 27.6 21.7 13.9 48.7 33.2 30.1 21.1 13.3 42.7 31.8 39.0 15.2 28.5 20.4 24.3 22.8 19.1 31.3 27.0 15.4 37.7 20.0 25.2 24.6 14.8 31.9 49.1 60.4 24.9 22.7 50.5 13.2 2.1 1.4 0.9 2.0 1.2 1.7 2.3 1.9 1.8 1.3 2.4 2.0 1.9 0.3 3.3 1.2 1.8 1.5 0.7 13.8 14.3 18.0 18.2 14.2 13.3 14.2 13.5 14.6 12.0 14.2 16.7 33.6 0.0 14.3 10.1 46.3 38.0 67.8 6.0 89.4 176.1 33.1 40.9 17.7 21.5 11.1 29.5 221.0 55.3 55.8 17.2 29.4 9.0 5.9 26.8 51.8 36.5 14.4 27.5 31.0 8.2 32.6 38.4 20.4 28.2 19.7 49.0 31.1 19.4 23.6 75.7 32.9 26.9 6.1 23.2 22.8 8.9 58.1 24.7 12.4 9.4 14.5 47.2 45.3 15.1 28.9 7.3 11.6 48.2 37.9 56.8 14.2 22.7 8.5 176.3 46.0 45.5 38.8 164.6 107.3 48.8 39.9 71.4 49.5 60.3 26.1 51.5 PDE4A DPDE2 ENSG00000065989 "Phosphodiesterase 4A" P27815 19 10416773-10469630 "Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" Hydrolase "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Langerhans cells: 190.8;Late spermatids: 197.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HMC-1: 36.5;NB-4: 43.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB017632, HPA043310, HPA076091" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 47: Non-specific - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 25: Spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB017632: AB_1127109, HPA043310: AB_2678419, HPA076091: AB_2686775" "unprognostic (1.29e-2)" "unprognostic (3.98e-2)" "unprognostic (8.91e-2)" "unprognostic (1.82e-1)" "unprognostic (7.00e-2)" "unprognostic (6.84e-2)" "unprognostic (1.54e-2)" "unprognostic (4.39e-2)" "unprognostic (7.91e-2)" "unprognostic (1.52e-2)" "unprognostic (6.90e-2)" "unprognostic (2.41e-1)" "unprognostic (2.27e-2)" "unprognostic (1.64e-2)" "unprognostic (2.57e-2)" "unprognostic (1.67e-1)" "unprognostic (2.15e-1)" 13.7 5.6 10.9 5.9 12.5 5.4 9.7 3.0 32.3 12.4 0.0 11.0 2.7 9.8 1.4 4.1 7.5 6.6 12.5 11.8 7.9 7.0 2.5 13.0 3.2 21.9 7.1 1.5 12.7 22.2 3.9 6.5 20.8 8.4 4.0 5.3 9.8 4.8 37.9 5.4 6.5 6.2 1.1 8.2 12.9 24.5 13.0 1.6 11.0 16.9 2.6 8.2 8.2 15.7 0.1 2.5 0.5 6.7 18.7 11.1 3.7 5.6 11.1 0.7 1.9 6.0 5.4 2.6 16.1 14.6 0.4 0.6 3.9 0.7 0.4 6.7 5.5 23.7 8.1 6.7 12.3 3.9 36.5 8.3 0.8 6.2 0.0 0.7 5.3 2.1 18.9 5.5 4.0 1.7 2.3 43.3 2.9 6.7 4.7 15.6 3.7 20.3 0.9 1.4 4.2 1.5 0.4 0.2 6.2 1.0 0.8 7.8 11.2 8.3 10.5 5.7 3.7 10.9 0.9 12.4 3.5 0.3 6.7 4.1 1.7 3.4 0.8 2.5 0.4 0.1 0.3 1.1 2.0 0.0 0.0 0.4 0.1 3.0 2.7 0.1 0.7 1.1 10.9 12.5 3.0 32.3 11.8 7.9 21.9 7.1 20.8 1.1 13.0 15.7 9.4 3.2 11.6 6.2 10.8 10.1 2.6 2.5 1.8 25.6 6.4 4.3 7.7 8.6 5.5 9.2 0.0 0.5 58.9 7.1 0.0 3.1 48.9 2.1 20.7 8.6 0.0 1.7 39.4 12.9 4.8 12.1 7.1 3.6 31.8 0.3 10.4 0.9 10.2 55.5 43.5 5.1 6.1 22.1 190.8 197.0 17.4 53.9 14.2 12.2 15.4 1.2 22.6 12.5 1.5 12.3 3.8 18.0 27.0 3.0 0.1 0.2 6.9 3.6 6.6 9.0 10.2 8.6 8.5 0.5 8.1 0.4 37.0 1.0 6.8 1.3 PDE4D DPDE3 ENSG00000113448 "Phosphodiesterase 4D" Q08499 5 58969038-60522120 "Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins" Hydrolase "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 74.9;skeletal muscle: 70.4" "Cell type enhanced" "Detected in many" "Astrocytes: 619.3;Excitatory neurons: 2969.7;Inhibitory neurons: 1116.9;Oligodendrocyte precursor cells: 848.0;Oligodendrocytes: 443.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in many" 5 "eosinophil: 57.9" "Lineage enriched" "Detected in many" 5 "granulocytes: 57.9" "Cell line enhanced" "Detected in many" "A549: 62.2;AN3-CA: 70.4;HeLa: 104.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045895 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 20: HeLa - Mitochondria" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Cytosol "HPA045895: AB_10960275" "unprognostic (1.14e-1)" "unprognostic (8.73e-3)" "unprognostic (4.35e-2)" "unprognostic (7.87e-2)" "unprognostic (5.97e-2)" "unprognostic (2.03e-1)" "unprognostic (8.10e-4)" "unprognostic (1.17e-1)" "unprognostic (6.59e-2)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (2.65e-1)" "prognostic favorable (4.00e-5)" "unprognostic (1.51e-1)" "unprognostic (8.20e-2)" "unprognostic (1.77e-2)" "unprognostic (2.56e-2)" 8.9 1.3 3.3 9.8 9.9 74.9 4.6 0.0 11.3 5.3 0.0 21.0 5.5 7.4 18.4 13.7 7.3 9.1 15.7 4.4 4.2 17.2 2.8 13.3 5.3 7.0 2.0 3.0 3.7 5.5 6.7 16.6 1.2 19.9 15.0 21.4 7.4 21.2 70.4 4.5 7.0 15.3 0.8 4.0 10.3 3.4 3.8 8.6 7.4 34.4 5.6 22.0 8.2 5.7 0.1 62.2 12.8 70.4 2.3 4.4 10.1 1.6 1.8 3.4 4.9 24.5 2.0 4.8 0.2 0.5 10.3 10.6 0.0 2.8 5.9 2.9 7.0 9.2 104.6 5.3 9.1 4.4 0.7 9.3 2.3 9.6 1.7 1.1 7.3 0.3 0.0 1.6 5.9 4.5 3.6 10.3 2.4 1.8 3.2 1.2 16.0 10.5 15.9 23.5 2.3 8.0 16.4 27.1 14.2 11.4 1.9 9.3 8.5 0.9 0.2 12.0 3.3 3.5 0.1 0.5 10.3 17.3 2.7 4.2 2.0 57.9 1.5 0.1 1.5 11.0 1.4 0.7 1.4 11.3 0.9 0.7 3.1 0.4 0.2 0.0 0.8 1.1 3.3 9.9 0.0 11.3 4.4 4.2 7.0 2.0 1.2 0.8 3.8 5.7 22.5 32.1 110.0 619.3 32.3 10.6 30.1 6.6 35.3 20.2 5.1 2.7 35.7 8.6 30.2 42.3 73.0 11.3 118.6 28.1 11.7 0.6 21.4 19.0 8.6 16.9 33.4 2.1 2969.7 1.8 25.7 27.5 40.2 21.9 22.2 0.3 17.2 0.8 5.2 1.7 1116.9 18.2 6.1 4.8 11.1 36.6 1.5 29.5 10.6 407.5 6.0 12.0 29.9 848.0 443.3 8.2 11.9 4.9 44.4 43.3 8.9 27.5 19.4 52.8 0.0 64.0 6.3 1.1 7.7 40.6 8.8 3.1 94.3 1.1 11.7 26.5 PDGFC "fallotein, SCDGF" ENSG00000145431 "Platelet derived growth factor C" Q9NRA1 4 156760454-156971799 "Predicted secreted proteins, RAS pathway related proteins" "Developmental protein, Growth factor, Mitogen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "parathyroid gland: 20.3" "Cell type enhanced" "Detected in many" "Astrocytes: 98.6;Granulosa cells: 124.1;Microglial cells: 85.3;Oligodendrocyte precursor cells: 233.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 60.0;hTERT-RPE1: 56.8;U-138 MG: 41.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA009134 Approved Supported "Plasma membrane,Cytosol" "Secreted to blood" NA NA 37000 "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "HPA009134: AB_10601981" "unprognostic (3.12e-1)" "unprognostic (1.91e-2)" "unprognostic (5.79e-2)" "unprognostic (3.67e-2)" "unprognostic (3.97e-1)" "unprognostic (3.41e-2)" "unprognostic (8.78e-2)" "unprognostic (1.60e-2)" "unprognostic (1.36e-1)" "unprognostic (8.12e-2)" "unprognostic (2.43e-3)" "unprognostic (1.14e-1)" "prognostic favorable (1.35e-5)" "prognostic unfavorable (3.05e-4)" "unprognostic (1.25e-1)" "unprognostic (1.19e-2)" "prognostic unfavorable (3.17e-4)" 4.8 4.0 0.9 1.3 1.0 0.6 7.5 0.4 1.0 9.2 0.7 2.3 2.0 9.9 2.1 3.3 6.7 4.8 2.6 1.0 0.8 5.5 5.1 3.1 1.1 0.8 0.7 7.7 4.3 20.3 0.4 4.5 0.7 8.7 2.0 0.7 8.4 7.0 1.2 1.6 2.8 9.4 0.9 1.3 2.8 0.9 1.1 2.0 6.5 1.2 1.0 3.2 1.2 1.0 2.5 3.7 38.6 25.4 7.0 13.4 1.0 21.5 21.5 12.0 16.1 2.2 9.4 0.0 3.8 60.0 9.2 2.6 10.8 13.4 16.5 0.0 5.0 25.5 3.2 2.4 18.3 3.9 0.3 14.2 6.6 30.6 21.7 56.8 6.0 0.1 0.1 0.1 30.2 0.1 0.0 0.0 0.4 0.0 1.7 0.0 8.1 0.0 22.5 0.9 0.0 0.0 0.0 0.2 0.4 6.0 3.1 1.3 28.3 41.7 0.4 10.9 17.3 0.0 0.0 0.0 16.1 0.0 1.6 0.0 0.4 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.9 1.0 0.4 1.0 1.0 0.8 0.8 0.7 0.7 0.9 1.1 1.0 2.4 6.4 14.2 98.6 0.7 49.6 22.7 12.4 25.0 2.0 14.7 13.6 16.8 58.6 7.8 12.9 0.0 0.6 3.4 0.5 0.0 15.4 30.5 6.9 15.0 7.3 0.0 5.5 64.4 7.1 0.3 18.6 8.2 11.4 1.3 124.1 10.0 15.9 13.0 0.0 32.1 2.1 4.1 34.4 21.6 23.8 5.3 32.1 10.6 85.3 14.2 6.3 0.0 233.2 3.0 18.0 0.5 23.0 1.4 8.7 2.4 18.6 3.5 0.5 6.6 34.8 18.2 0.7 2.9 3.4 13.5 0.5 0.9 13.8 2.1 4.8 PDZD2 "KIAA0300, PDZK3" ENSG00000133401 "PDZ domain containing 2" O15018 5 31639131-32110932 "Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 24.8" "Cell type enhanced" "Detected in many" "Early spermatids: 232.9;Excitatory neurons: 313.2;Oligodendrocyte precursor cells: 745.0" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 4 "basal ganglia: 24.8;cerebral cortex: 15.7" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 8.1;EFO-21: 4.5;SiHa: 11.6;SK-BR-3: 10.6;T-47d: 5.5" "Low region specificity" "Detected in all" "CAB020784, HPA036503, HPA036504, HPA064387, HPA076072" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 82: Adipose tissue - ECM organization" "Cluster 28: BEWO - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB020784: , HPA036503: AB_2675161, HPA036504: , HPA064387: AB_2685252, HPA076072: " "unprognostic (3.65e-2)" "unprognostic (4.06e-2)" "unprognostic (6.63e-2)" "unprognostic (5.42e-5)" "unprognostic (2.39e-1)" "unprognostic (9.67e-3)" "unprognostic (2.55e-1)" "unprognostic (6.49e-2)" "unprognostic (3.38e-2)" "unprognostic (2.45e-2)" "unprognostic (1.71e-2)" "unprognostic (1.93e-1)" "unprognostic (2.33e-3)" "unprognostic (4.13e-2)" "unprognostic (6.92e-2)" "unprognostic (7.67e-2)" "unprognostic (1.79e-1)" 16.5 0.9 4.5 0.7 24.8 0.1 5.0 0.7 15.7 2.2 10.6 1.4 0.5 2.5 1.9 5.3 2.2 0.9 18.8 4.7 0.3 8.2 0.1 9.0 0.3 4.5 4.3 14.4 1.2 0.6 1.8 10.9 1.0 1.5 0.7 14.8 1.6 1.9 2.5 10.1 0.6 2.4 0.3 0.2 1.7 5.6 4.1 2.6 1.0 4.8 1.7 0.6 2.1 0.0 0.1 0.0 3.1 0.1 0.0 0.0 8.1 0.0 0.0 0.6 0.5 0.0 0.0 0.0 4.5 0.0 1.2 4.3 1.7 0.9 0.0 0.0 0.2 0.0 2.6 0.0 0.0 0.0 2.2 0.2 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.9 0.0 0.7 0.0 0.0 0.0 3.5 0.0 0.1 0.7 11.6 10.6 0.0 2.6 5.5 0.0 0.0 0.0 2.2 0.0 0.5 0.0 0.0 2.7 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.5 24.8 0.7 15.7 4.7 0.3 4.5 4.3 1.0 0.3 4.1 0.0 26.2 44.8 38.6 39.2 0.2 16.8 4.4 14.0 13.6 7.0 10.6 6.9 53.9 0.0 9.3 5.5 98.0 25.5 1.9 0.1 0.0 0.2 232.9 9.7 16.9 14.7 0.0 1.3 313.2 0.2 3.4 8.6 7.7 33.2 1.3 18.7 5.7 0.2 2.2 15.2 113.2 0.0 4.1 0.3 3.1 55.2 7.5 1.0 7.2 87.1 0.2 6.4 0.0 745.0 104.7 3.5 0.0 10.5 0.1 3.5 0.0 8.2 2.8 62.1 46.0 7.3 13.4 12.3 3.8 15.1 18.5 21.1 1.3 46.8 0.0 1.8 PDZD8 "bA129M16.2, FLJ34427, PDZK8" ENSG00000165650 "PDZ domain containing 8" Q8NEN9 10 117277274-117375440 "Predicted intracellular proteins, Transporters" "Host-virus interaction, Lipid transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 73.0" "Cell type enhanced" "Detected in all" "Early spermatids: 208.7;Late spermatids: 477.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "HEL: 124.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015716, HPA051610" Uncertain Approved "Nucleoli fibrillar center,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 25: Spermatids - Spermatogenesis" "Nucleoli fibrillar center" "Plasma membrane" "HPA015716: AB_1855162, HPA051610: AB_2681549" "unprognostic (1.12e-1)" "unprognostic (2.87e-1)" "unprognostic (9.65e-3)" "unprognostic (2.75e-2)" "unprognostic (6.29e-2)" "unprognostic (3.36e-2)" "unprognostic (2.42e-1)" "unprognostic (1.43e-1)" "unprognostic (2.53e-1)" "unprognostic (3.10e-2)" "prognostic unfavorable (6.10e-4)" "unprognostic (1.90e-2)" "unprognostic (5.37e-3)" "unprognostic (7.60e-3)" "unprognostic (1.44e-2)" "unprognostic (3.18e-2)" "unprognostic (2.01e-2)" 7.1 7.0 8.9 4.7 12.1 73.0 4.7 15.7 8.6 7.9 17.9 9.3 14.0 9.1 14.1 10.8 6.8 9.7 5.1 8.1 11.8 13.1 15.8 6.0 3.2 11.9 13.8 8.9 14.1 28.3 4.2 5.4 12.2 6.4 11.2 14.1 12.9 10.6 4.9 5.5 10.6 6.9 11.3 3.7 10.4 13.2 12.5 5.8 6.8 5.8 3.6 6.6 5.8 13.2 12.6 21.1 7.6 14.7 12.8 11.4 4.3 11.9 10.2 5.2 4.2 10.7 16.4 14.7 10.5 18.1 6.0 18.4 13.4 12.6 10.3 9.4 11.8 124.3 8.6 10.6 9.4 52.4 11.2 11.2 14.7 9.5 27.9 19.3 9.3 12.1 11.5 15.0 13.0 5.1 10.2 6.7 6.0 6.6 18.8 8.2 29.2 6.4 15.5 9.0 6.0 9.6 12.6 5.4 9.7 6.9 3.7 7.6 15.1 8.6 9.4 15.8 20.5 8.0 7.2 10.5 10.8 23.6 7.7 1.4 0.5 2.6 0.9 0.5 0.9 0.3 0.7 0.7 0.7 0.4 0.5 0.7 2.3 1.2 0.9 0.5 0.3 0.2 8.9 12.1 15.7 8.6 8.1 11.8 11.9 13.8 12.2 11.3 12.5 13.2 22.1 12.8 30.7 32.3 13.7 29.7 24.4 10.3 24.5 31.9 16.4 17.0 19.8 40.0 21.0 18.4 22.9 9.8 36.1 26.9 9.8 31.9 208.7 78.3 46.7 24.0 33.7 82.0 49.2 81.9 7.2 27.3 48.4 111.2 44.2 14.6 18.9 58.6 7.5 32.0 61.0 38.8 10.2 16.0 31.8 477.6 23.6 25.2 23.2 30.0 15.5 29.0 23.7 51.8 56.4 57.6 23.1 28.6 28.1 41.1 27.0 26.5 28.5 45.0 26.3 46.3 24.5 25.8 29.1 36.3 32.4 6.7 28.4 90.8 50.2 44.6 PEBP1 "HCNP, PBP, PEBP, RKIP" ENSG00000089220 "Phosphatidylethanolamine binding protein 1" P30086 12 118136124-118145584 "Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 2083.1" "Cell type enhanced" "Detected in all" "Distal tubular cells: 3705.6;Hepatocytes: 2242.4;Proximal enterocytes: 2177.7;Proximal tubular cells: 4542.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Not detected" "Not detected" "HPA008819, CAB009906, CAB013493, HPA063904" Enhanced Approved "Plasma membrane,Cytosol" NA NA 51000000 "Cluster 30: Non-specific - Translation" "Cluster 35: Non-specific - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "CAB009906: AB_2163173, CAB013493: AB_2533305, HPA008819: AB_1855173, HPA063904: AB_2732708" "unprognostic (4.57e-1)" "unprognostic (1.03e-3)" "unprognostic (3.28e-2)" "unprognostic (3.39e-3)" "unprognostic (2.05e-1)" "unprognostic (1.59e-1)" "unprognostic (1.24e-2)" "unprognostic (7.35e-3)" "unprognostic (5.67e-2)" "unprognostic (3.55e-2)" "prognostic favorable (1.52e-4)" "unprognostic (1.63e-1)" "prognostic favorable (2.15e-13)" "unprognostic (2.17e-1)" "unprognostic (7.72e-2)" "unprognostic (7.96e-2)" "unprognostic (8.80e-2)" 217.9 1754.1 941.2 84.0 966.0 121.8 235.5 987.9 1049.0 258.0 958.4 208.9 601.4 186.6 383.7 219.5 218.4 154.8 463.8 932.6 951.5 1046.1 2083.1 176.4 122.7 959.0 965.9 335.9 357.5 1162.7 292.3 128.8 982.6 261.6 191.2 336.1 344.5 233.2 580.3 190.3 510.6 167.6 1006.6 121.2 201.7 152.2 1025.0 138.1 739.7 546.8 160.2 200.8 179.0 1081.7 289.2 241.6 340.0 348.8 493.5 250.2 500.0 214.5 262.3 347.7 177.1 151.6 96.4 439.6 221.3 336.2 139.9 194.4 495.0 202.8 257.7 115.1 454.2 220.0 274.7 1021.7 289.2 403.6 94.5 240.8 334.7 203.9 140.0 396.1 162.7 240.9 375.8 169.2 356.4 346.3 226.8 813.7 319.7 243.1 273.9 446.1 235.6 829.7 428.7 277.2 397.5 306.9 439.9 306.2 446.0 200.4 443.6 293.0 168.9 253.7 147.0 254.0 237.3 161.6 315.1 234.1 301.1 303.2 280.9 5.0 67.5 20.0 155.2 76.4 247.0 271.7 258.9 193.1 205.1 210.0 244.6 201.2 8.0 138.1 68.6 231.6 259.7 258.4 941.2 966.0 987.9 1049.0 932.6 951.5 959.0 965.9 982.6 1006.6 1025.0 1081.7 193.7 403.8 433.3 101.5 230.9 318.1 449.3 367.6 288.5 539.4 538.4 590.7 697.3 713.4 243.2 783.5 95.9 999.6 144.6 207.1 3705.6 507.9 44.3 499.3 319.0 186.5 320.6 218.1 93.7 244.6 862.3 347.9 169.2 369.8 371.8 419.7 213.8 2242.4 591.6 721.8 99.6 378.8 335.7 201.4 239.0 84.4 543.1 195.3 743.5 53.4 296.8 1792.2 101.0 39.2 199.8 184.2 313.3 731.6 279.3 517.4 2177.7 4542.6 291.6 411.6 368.1 337.5 347.8 330.6 145.7 367.7 325.2 615.5 216.7 921.6 631.3 399.5 PECAM1 CD31 ENSG00000261371 "Platelet and endothelial cell adhesion molecule 1" P16284 17 64319415-64413776 "Cancer-related genes, Candidate cardiovascular disease genes, CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Phagocytosis" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "placenta: 455.1" "Cell type enhanced" "Detected in many" "Adipocytes: 672.9;Endothelial cells: 468.2;Hepatic stellate cells: 275.3;Macrophages: 143.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "non-classical monocyte: 702.3" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in many" 5 "HUVEC TERT2: 773.0;TIME: 537.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004690, HPA004871" Enhanced Approved "Nucleoli,Plasma membrane" NA NA 110000000 "Cluster 51: Monocytes - Innate immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" Nucleoli "HPA004690: AB_1078462, HPA004871: " "unprognostic (2.79e-1)" "unprognostic (2.14e-1)" "unprognostic (2.79e-2)" "unprognostic (2.76e-1)" "unprognostic (1.34e-1)" "unprognostic (4.42e-3)" "unprognostic (2.84e-1)" "unprognostic (2.37e-1)" "unprognostic (2.57e-1)" "unprognostic (7.25e-2)" "unprognostic (4.53e-2)" "unprognostic (9.68e-2)" "prognostic unfavorable (8.98e-5)" "unprognostic (9.72e-3)" "unprognostic (9.57e-2)" "unprognostic (1.56e-1)" "unprognostic (4.16e-2)" 195.6 21.4 20.3 78.9 21.4 35.5 128.5 21.9 25.3 54.9 21.7 37.9 29.7 51.1 9.2 54.3 45.1 88.6 70.3 18.0 22.2 43.6 22.4 204.9 68.0 24.7 23.1 10.7 21.3 29.9 9.7 455.1 24.1 23.5 37.7 4.0 33.4 24.5 35.7 36.2 39.4 83.5 26.3 94.9 30.9 5.0 28.1 62.4 69.8 97.0 60.4 84.0 35.7 22.2 0.1 0.3 1.3 0.1 1.1 1.5 0.4 0.2 0.3 0.0 0.1 4.7 0.1 4.2 121.1 0.0 0.2 0.1 0.0 0.0 0.0 0.5 0.0 95.0 1.8 2.2 3.7 0.5 0.3 0.3 0.0 0.8 0.2 1.6 773.0 34.1 2.3 57.8 0.1 0.4 33.3 8.1 0.1 0.0 9.1 1.4 15.3 3.8 0.0 0.1 0.4 0.3 1.8 0.0 0.1 0.2 0.0 48.5 537.8 0.8 0.5 0.9 0.2 3.4 6.3 6.8 1.6 6.7 0.1 54.8 263.9 219.2 19.8 419.6 18.9 26.7 2.2 46.6 154.0 32.7 36.3 68.6 392.0 40.3 702.3 88.6 2.1 224.2 20.3 21.4 21.9 25.3 18.0 22.2 24.7 23.1 24.1 26.3 28.1 22.2 672.9 16.0 37.9 0.7 24.4 0.0 0.5 0.0 4.0 0.0 4.8 4.6 23.3 1.5 3.1 9.2 0.0 0.5 50.1 0.0 0.0 0.8 0.9 1.1 1.1 468.2 0.0 17.9 1.2 0.2 4.0 22.0 0.0 1.6 8.8 0.0 275.3 3.0 45.8 0.0 1.2 0.0 0.0 110.4 0.0 1.1 2.5 143.9 0.0 47.8 93.8 0.3 26.8 0.5 1.3 0.1 0.0 1.9 109.1 1.3 0.0 0.5 7.3 1.2 0.0 6.9 15.8 0.1 0.5 1.6 0.0 0.8 21.2 4.3 0.1 1.0 PGAP3 "CAB2, MGC9753, PER1, PERLD1, PP1498" ENSG00000161395 "Post-GPI attachment to proteins phospholipase 3" Q96FM1 17 39671122-39696797 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in many" 6 "OE19: 800.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016591 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 22: Non-specific - Unknown function" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "HPA016591: AB_1855203" "unprognostic (1.29e-1)" "unprognostic (8.64e-2)" "unprognostic (1.65e-1)" "unprognostic (6.53e-3)" "unprognostic (9.19e-2)" "unprognostic (1.68e-2)" "prognostic favorable (3.94e-4)" "unprognostic (1.61e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (6.82e-4)" "unprognostic (1.57e-2)" "unprognostic (7.79e-2)" "prognostic favorable (3.89e-4)" "unprognostic (5.16e-2)" "unprognostic (1.31e-1)" "unprognostic (9.05e-2)" "unprognostic (1.94e-2)" 10.5 11.9 17.0 5.6 17.2 5.0 12.9 14.0 19.6 14.6 16.2 18.6 14.9 11.3 18.3 25.8 15.9 13.4 14.8 17.5 16.7 20.6 35.6 12.1 7.4 14.9 15.4 13.5 27.1 22.7 14.9 11.8 14.6 18.5 13.7 7.1 25.1 11.7 8.3 21.0 17.1 6.1 14.7 12.3 16.6 9.1 16.5 4.8 27.1 4.5 7.5 12.2 13.7 15.5 3.7 9.6 7.7 7.0 7.9 8.1 7.9 4.3 10.1 6.7 6.1 5.4 23.8 4.2 19.7 8.3 2.2 12.6 2.4 2.9 3.1 8.6 7.7 5.2 6.0 9.3 10.6 12.9 12.8 14.9 15.0 3.1 6.8 7.6 2.2 1.9 4.9 9.6 6.1 8.7 2.9 11.7 7.6 800.4 2.1 3.2 4.7 12.1 10.7 12.0 7.1 4.7 11.9 134.0 6.9 0.8 11.4 12.4 3.4 7.2 7.6 3.5 3.3 8.5 2.0 1.4 8.1 4.9 8.1 2.6 7.2 4.6 15.2 11.6 8.3 8.1 10.6 12.5 5.7 7.7 10.1 10.1 2.0 10.4 4.3 3.9 5.4 7.3 17.0 17.2 14.0 19.6 17.5 16.7 14.9 15.4 14.6 14.7 16.5 15.5 6.5 3.2 14.9 7.8 3.7 3.8 3.3 5.6 3.4 12.6 9.1 7.0 7.7 14.3 10.1 14.7 8.4 8.1 5.3 20.3 1.9 7.6 0.1 3.5 4.5 5.0 8.4 3.0 9.0 11.1 6.5 5.1 9.2 5.7 8.9 6.8 4.6 9.0 4.4 13.5 6.3 15.3 8.2 5.1 2.8 0.1 3.1 3.7 1.8 2.8 1.9 7.5 4.1 9.0 6.1 6.3 13.9 1.5 2.8 3.7 22.9 3.4 4.9 22.1 0.0 5.0 3.3 0.7 2.4 8.1 2.8 10.4 4.9 5.8 13.3 3.1 PGLYRP4 "PGLYRPIbeta, PGRP-Ibeta, PGRPIB, SBBI67" ENSG00000163218 "Peptidoglycan recognition protein 4" Q96LB8 1 153330120-153348841 "Metabolic proteins, Predicted secreted proteins" "Immunity, Innate immunity" "Antibiotic, Antimicrobial" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "cervix: 8.5;esophagus: 8.2;skin 1: 15.1;vagina: 10.3" "Group enriched" "Detected in some" 4 "Basal respiratory cells: 30.1;Club cells: 9.7" "Cancer enhanced" "Detected in some" "head and neck cancer: 7.8" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HaCaT: 3.7;HDLM-2: 2.2;Karpas-707: 1.8" "Not detected" "Not detected" "Low region specificity" "Detected in some" CAB025879 Approved "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB025879: " "unprognostic (2.76e-2)" "unprognostic (1.19e-1)" "unprognostic (6.10e-2)" "unprognostic (1.34e-2)" "unprognostic (3.61e-3)" "unprognostic (1.46e-1)" "unprognostic (3.13e-1)" "unprognostic (5.42e-2)" "unprognostic (3.99e-2)" "unprognostic (1.07e-2)" "unprognostic (2.15e-1)" "unprognostic (1.81e-1)" "unprognostic (1.88e-1)" 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 1.4 0.0 0.0 15.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 2.3 0.0 10.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.7 0.0 0.0 0.0 2.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.4 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.1 30.1 0.6 0.0 0.0 0.1 0.3 0.0 9.7 0.0 0.0 0.0 0.0 0.1 0.0 1.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.2 2.0 0.0 0.3 0.3 0.3 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.1 0.4 0.0 2.4 0.0 0.0 0.0 0.3 0.0 0.0 4.0 3.4 0.3 0.0 0.0 0.2 0.2 PHACTR2 "C6orf56, KIAA0680" ENSG00000112419 "Phosphatase and actin regulator 2" O75167 6 143536845-143831185 "Predicted intracellular proteins" "Actin-binding, Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in all" 5 "choroid plexus: 164.2;placenta: 83.8" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 214.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "TIME: 82.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031719, HPA031720, HPA031725" Approved Approved "Golgi apparatus,Plasma membrane" NA NA "Cluster 16: MAIT-cells - Unknown function" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Golgi apparatus" "Plasma membrane" "HPA031719: AB_10696055, HPA031720: AB_10670553, HPA031725: AB_10610279" "unprognostic (3.25e-3)" "unprognostic (1.07e-1)" "unprognostic (4.39e-2)" "unprognostic (5.25e-2)" "unprognostic (1.90e-2)" "unprognostic (8.38e-2)" "unprognostic (3.19e-2)" "unprognostic (9.92e-2)" "unprognostic (7.46e-2)" "unprognostic (3.61e-2)" "unprognostic (2.49e-1)" "unprognostic (2.80e-1)" "prognostic favorable (1.99e-4)" "unprognostic (3.60e-1)" "unprognostic (5.08e-2)" "unprognostic (9.92e-2)" "unprognostic (1.17e-1)" 11.6 25.4 7.0 7.8 9.0 7.6 5.5 4.3 5.7 8.1 164.2 8.5 7.5 9.9 3.6 22.0 5.7 8.4 12.4 10.0 4.9 5.9 7.9 15.7 7.8 12.3 10.3 6.5 4.9 13.1 4.0 83.8 15.1 10.3 8.5 2.7 6.0 6.9 4.5 2.7 6.1 9.8 3.5 13.5 12.0 6.5 16.5 2.7 15.5 7.3 6.7 7.6 6.4 4.5 21.9 13.5 3.6 26.6 3.7 8.0 15.3 18.0 27.2 7.7 9.6 23.9 9.5 1.2 47.5 51.7 5.4 6.5 2.0 17.9 9.1 18.1 8.5 35.5 14.7 14.0 6.1 9.1 10.5 11.2 9.8 7.7 24.9 11.8 47.0 6.7 10.2 0.1 12.4 24.0 1.3 2.1 26.8 7.7 3.8 3.3 26.3 0.2 9.3 19.2 5.2 5.2 20.0 26.1 0.3 13.4 9.8 13.1 82.2 34.9 18.2 15.2 11.8 0.2 0.1 0.3 8.6 9.5 3.2 6.0 3.5 6.7 3.3 2.5 12.3 0.4 4.0 4.4 3.3 0.2 2.4 1.6 1.8 3.5 2.7 3.2 5.5 1.9 7.0 9.0 4.3 5.7 10.0 4.9 12.3 10.3 15.1 3.5 16.5 4.5 160.9 214.7 94.5 41.4 11.7 24.2 16.0 19.5 47.3 37.0 14.2 13.8 71.8 32.9 73.2 22.0 2.1 84.7 27.5 58.9 13.7 30.5 10.1 49.6 43.7 158.6 21.6 32.8 55.2 22.5 49.8 144.8 54.6 64.7 38.7 34.9 157.1 27.6 35.4 101.0 133.8 19.2 24.4 121.1 40.2 23.2 103.2 52.5 24.9 77.8 71.7 10.3 15.5 5.5 20.9 49.4 22.3 120.0 10.6 63.3 20.2 24.8 51.1 3.0 98.6 95.9 83.5 3.1 2.3 33.0 17.2 52.5 51.3 127.9 26.3 30.9 PHF20L1 "CGI-72, FLJ13649, FLJ21615, MGC64923, TDRD20B" ENSG00000129292 "PHD finger protein 20 like 1" A8MW92 8 132775358-132848807 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA025060, HPA028417" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA025060: AB_10599822, HPA028417: AB_10602278" "unprognostic (9.12e-3)" "unprognostic (2.29e-1)" "unprognostic (2.77e-1)" "unprognostic (2.10e-3)" "unprognostic (1.25e-1)" "unprognostic (1.51e-1)" "unprognostic (2.79e-2)" "unprognostic (7.53e-2)" "unprognostic (9.66e-2)" "unprognostic (1.24e-2)" "unprognostic (8.85e-2)" "unprognostic (1.19e-1)" "unprognostic (1.70e-2)" "unprognostic (1.58e-1)" "unprognostic (1.78e-1)" "unprognostic (2.24e-2)" "unprognostic (7.83e-2)" 12.1 14.0 8.0 13.5 9.6 24.9 10.9 10.4 11.3 11.6 9.9 9.2 9.4 11.4 10.0 11.6 7.9 10.7 17.5 8.0 6.4 10.7 13.4 10.3 11.8 6.5 6.7 11.3 8.9 15.7 8.7 12.4 6.7 9.9 10.1 12.5 9.6 8.0 16.7 7.7 9.9 11.5 5.7 11.5 9.3 13.5 7.2 25.6 22.7 18.5 12.4 12.8 8.9 9.8 20.9 20.6 33.1 19.1 25.3 29.9 11.9 30.1 23.4 20.2 19.7 11.5 14.0 23.8 25.6 30.3 17.4 12.0 22.5 16.0 24.9 40.4 16.1 25.5 24.3 8.2 26.6 20.7 17.6 22.5 19.4 21.1 31.1 19.5 22.6 37.2 32.1 36.4 30.4 21.0 67.6 9.2 14.7 23.8 27.1 32.6 22.1 20.6 16.5 17.8 81.4 23.8 19.1 13.5 24.5 13.8 26.5 23.0 29.6 32.6 25.9 21.5 29.1 21.5 29.9 30.3 28.8 35.8 29.6 3.5 3.8 7.0 2.1 2.4 2.1 2.1 1.9 2.5 3.6 2.2 2.8 2.2 12.6 3.0 3.6 2.9 2.5 1.5 8.0 9.6 10.4 11.3 8.0 6.4 6.5 6.7 6.7 5.7 7.2 9.8 65.9 25.6 51.6 74.4 51.1 33.6 52.6 48.2 40.9 55.7 40.5 38.0 88.5 25.8 57.2 36.8 43.8 29.7 92.9 35.1 23.5 37.3 81.2 39.8 73.4 55.2 43.7 37.9 133.9 31.3 32.0 51.6 41.8 48.9 60.2 60.1 36.0 33.4 36.6 53.8 192.2 29.0 44.7 39.6 49.3 49.5 40.0 84.2 23.2 83.4 67.5 50.9 78.2 104.5 117.5 40.6 26.4 42.9 66.6 40.4 41.5 25.7 30.8 54.1 46.0 68.1 58.9 115.1 45.9 44.9 36.2 45.0 65.8 61.4 30.9 66.7 PHLDB2 "FLJ21791, LL5b, LL5beta" ENSG00000144824 "Pleckstrin homology like domain family B member 2" Q86SQ0 3 111732497-111976517 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 249.9;Basal prostatic cells: 189.9;Suprabasal keratinocytes: 114.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "A-431: 103.8;HaCaT: 105.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035146, HPA035147" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA035146: AB_10600927, HPA035147: AB_2674492" "unprognostic (2.83e-2)" "unprognostic (4.93e-3)" "unprognostic (2.15e-2)" "unprognostic (8.01e-2)" "unprognostic (1.00e-2)" "prognostic unfavorable (2.59e-4)" "unprognostic (5.14e-2)" "unprognostic (2.20e-2)" "unprognostic (1.43e-1)" "unprognostic (9.03e-2)" "unprognostic (2.00e-2)" "unprognostic (3.53e-1)" "prognostic favorable (7.03e-8)" "unprognostic (3.24e-3)" "unprognostic (3.47e-2)" "unprognostic (1.53e-1)" "unprognostic (2.83e-1)" 25.6 7.2 2.2 15.7 2.3 1.5 11.3 0.9 4.0 10.6 10.3 29.0 6.0 20.4 7.4 11.1 13.3 15.3 42.7 0.9 0.5 31.5 35.6 17.6 5.1 1.2 1.8 8.9 10.0 1.8 5.7 40.8 1.6 16.4 8.6 0.5 10.6 25.7 4.8 7.0 7.7 24.3 1.6 16.5 11.7 2.8 3.9 5.0 6.2 8.7 3.2 26.5 10.5 2.0 103.8 11.2 62.2 0.1 19.8 32.3 25.5 58.3 28.5 37.8 44.5 32.1 7.5 0.0 59.6 22.6 38.2 105.2 0.9 37.5 68.6 1.6 1.5 0.0 26.1 10.6 21.3 0.2 0.3 38.1 21.9 26.1 48.1 42.5 61.8 1.0 0.1 0.4 11.5 0.2 4.2 0.1 25.3 1.0 19.3 9.0 80.1 0.0 22.2 24.5 1.6 4.7 57.6 1.1 5.9 34.1 2.1 0.3 54.4 10.2 85.2 27.4 14.3 5.4 0.2 0.2 10.4 0.1 19.9 0.1 0.0 0.0 2.6 0.0 1.8 0.2 1.8 2.9 0.0 0.4 0.0 1.1 0.2 1.0 0.0 0.5 0.4 0.8 2.2 2.3 0.9 4.0 0.9 0.5 1.2 1.8 1.6 1.6 3.9 2.0 30.9 80.1 7.5 2.6 1.6 249.9 189.9 33.3 33.0 0.2 11.6 9.8 95.8 25.8 16.8 33.1 2.1 27.0 13.0 0.6 23.5 62.6 12.9 3.7 15.3 44.8 10.8 2.7 51.7 20.5 51.5 40.3 14.3 26.2 7.0 1.2 35.3 35.2 3.5 0.0 9.5 3.4 8.2 2.5 20.6 5.3 14.3 2.9 23.2 39.4 1.0 0.1 23.7 4.5 1.8 45.4 0.5 22.6 2.8 60.1 0.0 30.9 6.8 0.3 13.1 21.0 95.9 0.5 3.3 17.7 114.7 66.8 6.7 2.7 1.9 84.0 PHOSPHO1 ENSG00000173868 "Phosphoethanolamine/phosphocholine phosphatase 1" Q8TCT1 17 49223366-49230787 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Mineral balance" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "testis: 103.0" "Cell type enriched" "Detected in some" 6 "Late spermatids: 1499.6" "Cancer enhanced" "Detected in some" "ovarian cancer: 2.6" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 160 "eosinophil: 171.1;neutrophil: 426.7" "Lineage enriched" "Detected in many" 228 "granulocytes: 426.7" "Cell line enhanced" "Detected in some" "Daudi: 5.7;EFO-21: 3.2;HDLM-2: 4.1;SuSa: 5.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA065025 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 25: Spermatids - Spermatogenesis" "Actin filaments" "Plasma membrane" "HPA065025: AB_2732727" "unprognostic (1.37e-1)" "unprognostic (3.01e-3)" "unprognostic (7.53e-2)" "unprognostic (4.41e-3)" "unprognostic (1.57e-1)" "unprognostic (4.70e-2)" "unprognostic (1.44e-1)" "unprognostic (1.39e-2)" "unprognostic (2.04e-1)" "unprognostic (6.88e-2)" "unprognostic (1.02e-2)" "unprognostic (2.88e-1)" "unprognostic (2.03e-1)" "unprognostic (1.45e-1)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (1.87e-1)" 2.5 1.3 1.5 3.4 3.4 19.0 0.5 6.3 3.9 0.4 0.6 0.7 2.9 0.7 0.2 1.0 1.3 2.2 1.8 1.8 7.3 1.3 1.0 2.3 1.6 8.8 6.2 0.3 1.2 0.2 0.6 6.4 7.4 0.8 0.0 0.7 1.2 0.3 3.4 1.3 3.0 0.4 6.9 14.2 0.9 103.0 5.5 0.3 0.7 3.2 0.2 0.9 0.5 6.1 0.0 1.0 0.0 0.8 0.1 0.1 0.0 0.2 0.2 0.0 0.1 1.5 0.0 5.7 3.2 0.0 2.1 0.0 0.9 0.3 0.1 4.1 0.1 0.7 0.7 0.2 0.0 0.0 0.6 0.2 0.0 0.3 0.0 0.4 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.2 0.7 1.2 2.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 5.4 0.1 0.1 2.2 0.3 1.7 1.1 0.0 0.1 0.2 0.3 1.5 2.0 0.1 0.2 0.6 171.1 0.4 1.5 0.3 0.1 0.1 0.2 0.4 0.0 0.0 0.2 426.7 0.5 1.8 0.0 0.1 1.1 1.5 3.4 6.3 3.9 1.8 7.3 8.8 6.2 7.4 6.9 5.5 6.1 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.0 1.2 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.1 0.3 0.0 0.0 0.0 205.8 0.0 0.0 1.4 0.0 8.6 0.7 0.0 1.4 0.3 0.0 0.0 0.0 0.0 0.4 0.0 2.6 0.0 1.4 0.0 0.0 0.3 0.0 1499.6 7.8 0.6 0.0 1.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 6.0 0.1 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 11.2 4.5 0.0 0.0 237.6 0.1 0.0 0.1 0.1 PI4KA "PI4K-ALPHA, pi4K230, PIK4CA" ENSG00000241973 "Phosphatidylinositol 4-kinase alpha" P42356 22 20707691-20859417 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 209.1;Inhibitory neurons: 127.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "K-562: 130.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009092, HPA075515" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 10: Brain - Neuronal signaling" "Cluster 1: K-562 - Erythropoiesis" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" Nucleoplasm "Plasma membrane" "CAB009092: AB_2164033, HPA075515: AB_2686753" "unprognostic (8.06e-2)" "unprognostic (1.53e-1)" "unprognostic (1.20e-2)" "unprognostic (4.45e-2)" "unprognostic (1.21e-1)" "unprognostic (5.01e-3)" "unprognostic (3.19e-2)" "prognostic favorable (5.24e-4)" "unprognostic (2.08e-1)" "unprognostic (4.21e-2)" "unprognostic (1.88e-2)" "unprognostic (1.29e-1)" "prognostic favorable (7.22e-5)" "unprognostic (1.37e-1)" "unprognostic (1.33e-1)" "unprognostic (2.35e-1)" "unprognostic (1.50e-1)" 18.8 21.6 45.2 19.2 61.0 24.1 16.8 2.1 74.4 20.4 9.6 23.7 15.8 24.2 9.9 14.3 19.5 13.5 21.5 65.3 9.0 21.3 25.2 19.1 20.5 14.6 4.8 21.4 18.7 34.5 25.2 17.9 14.5 19.5 14.9 27.7 16.5 16.9 23.6 15.1 22.9 21.9 0.0 21.0 26.0 25.7 8.6 34.3 18.0 15.9 18.0 22.2 16.9 43.3 24.5 20.2 17.4 26.3 48.7 29.1 24.9 21.6 32.6 31.3 30.4 15.9 10.2 45.6 12.6 43.9 30.7 21.1 33.4 20.9 19.0 38.9 50.9 47.1 27.1 18.3 24.3 47.0 36.1 26.2 12.9 26.7 14.7 20.4 25.8 13.8 130.2 37.6 24.6 33.8 41.6 16.0 13.8 43.4 20.6 41.1 38.1 8.5 17.3 38.3 42.6 31.0 28.4 32.6 22.6 24.3 27.6 21.3 26.2 56.4 29.1 21.1 18.5 28.6 31.3 35.8 37.4 33.2 24.1 2.1 3.7 5.3 3.2 3.8 3.1 3.4 3.6 3.9 2.5 3.4 3.6 5.0 5.1 7.0 3.3 8.5 4.3 2.2 45.2 61.0 2.1 74.4 65.3 9.0 14.6 4.8 14.5 0.0 8.6 43.3 13.0 12.8 30.4 65.6 14.7 10.1 6.5 7.6 9.6 35.8 17.2 14.4 30.2 20.0 10.5 7.3 47.9 17.8 21.5 19.7 1.9 9.7 36.5 10.3 17.9 15.5 19.2 12.4 209.1 6.3 19.6 15.6 38.7 15.8 12.0 13.8 11.4 19.7 20.1 37.0 127.4 16.7 10.2 21.0 12.6 25.3 19.9 20.2 10.6 39.4 10.9 23.1 16.5 50.3 88.4 8.9 9.7 24.0 15.5 10.1 23.8 10.3 9.6 25.4 26.3 14.5 19.3 35.3 29.6 14.1 9.8 20.0 15.3 26.1 14.3 8.9 PIEZO2 "C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771" ENSG00000154864 "Piezo type mechanosensitive ion channel component 2" Q9H5I5 18 10666483-11149569 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Transport" "Ion channel" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "brain: 58.3" "Cell type enriched" "Detected in many" 10 "Oligodendrocytes: 399.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 15.1;BJ hTERT+ SV40 Large T+: 16.9;BJ hTERT+ SV40 Large T+ RasG12V: 23.1;HeLa: 38.1;U-266/70: 23.0;U-698: 16.2" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA015986, HPA031974, HPA040616" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 20: HeLa - Mitochondria" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA015986: AB_1848395, HPA031974: AB_10603675, HPA040616: AB_2677043" "unprognostic (1.36e-1)" "unprognostic (1.92e-1)" "unprognostic (9.21e-2)" "unprognostic (2.53e-2)" "unprognostic (7.84e-2)" "unprognostic (3.16e-2)" "unprognostic (3.87e-2)" "unprognostic (4.34e-3)" "unprognostic (6.55e-2)" "unprognostic (3.89e-2)" "unprognostic (6.06e-2)" "unprognostic (2.23e-1)" "prognostic unfavorable (9.57e-7)" "unprognostic (1.12e-3)" "unprognostic (1.09e-1)" "unprognostic (9.04e-2)" "unprognostic (1.83e-2)" 1.2 0.5 7.3 1.3 20.2 0.4 1.7 14.7 14.4 1.0 0.1 3.9 0.3 0.6 1.6 5.1 1.1 5.3 0.3 7.9 8.7 1.1 4.1 6.6 0.9 18.2 14.4 0.7 1.8 0.5 0.9 0.0 18.2 3.0 1.4 0.1 0.3 2.9 0.1 1.1 1.1 2.1 8.5 2.7 1.6 1.2 16.8 0.8 1.5 0.2 0.6 5.3 0.7 58.3 0.0 1.8 15.1 0.0 0.0 0.0 0.0 0.8 4.4 16.9 23.1 0.0 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.0 10.6 0.0 0.5 0.0 38.1 8.8 5.2 0.0 0.1 0.1 0.3 4.3 1.2 0.1 5.2 0.6 0.0 0.3 2.7 0.0 0.3 0.0 4.5 6.7 0.0 0.0 0.0 7.0 0.0 5.3 12.7 0.0 0.1 0.0 0.8 6.7 0.0 4.5 0.0 0.0 5.8 0.3 0.9 23.0 0.2 16.2 0.0 0.0 10.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.3 20.2 14.7 14.4 7.9 8.7 18.2 14.4 18.2 8.5 16.8 58.3 3.3 0.0 5.3 2.0 0.0 0.8 0.3 0.0 0.0 0.0 2.3 0.8 1.6 10.0 0.6 0.0 0.0 0.1 0.0 0.0 0.0 0.3 31.7 0.2 0.2 9.9 0.0 0.0 2.5 0.2 0.0 11.2 2.6 0.0 5.1 0.1 17.2 5.9 1.0 0.0 37.0 0.0 0.0 3.2 0.8 11.9 0.0 0.6 0.0 9.4 0.0 0.0 0.0 2.0 399.6 0.1 0.0 0.0 0.4 0.1 0.0 0.1 7.3 0.0 6.6 0.9 4.5 0.3 1.4 0.2 0.9 0.4 0.6 32.9 0.0 0.1 PIGB ENSG00000069943 "Phosphatidylinositol glycan anchor biosynthesis class B" Q92521 15 55318960-55355648 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" "Glycosyltransferase, Transferase" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039929 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 32: U-937 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane, Cytosol" "HPA039929: AB_10673539" "unprognostic (1.91e-2)" "unprognostic (7.45e-2)" "unprognostic (3.00e-1)" "unprognostic (2.03e-2)" "unprognostic (2.96e-2)" "unprognostic (4.65e-2)" "unprognostic (2.04e-1)" "unprognostic (3.37e-3)" "unprognostic (7.52e-2)" "unprognostic (3.52e-2)" "unprognostic (2.56e-2)" "unprognostic (4.27e-2)" "unprognostic (2.13e-1)" "unprognostic (1.30e-1)" "unprognostic (2.86e-1)" "unprognostic (5.93e-2)" "unprognostic (4.24e-2)" 6.4 4.8 2.3 5.8 2.6 9.1 9.0 2.8 2.6 5.5 3.1 7.0 7.5 6.4 11.0 5.7 7.8 6.3 2.8 2.5 3.3 10.3 9.4 6.3 8.2 2.8 2.7 4.7 5.7 10.6 3.9 4.8 2.6 7.7 7.8 7.9 4.3 6.8 1.5 6.1 5.8 5.6 2.7 6.1 7.6 6.5 2.7 6.3 13.3 1.8 8.6 7.5 3.7 3.1 10.5 12.2 5.8 4.1 6.6 13.2 7.8 9.0 19.9 10.4 17.8 5.1 10.3 10.9 10.4 12.9 15.6 18.3 3.3 9.5 8.6 10.4 6.4 10.9 13.6 6.7 11.9 30.8 8.7 12.5 11.4 7.9 10.7 13.8 13.6 9.2 12.2 6.9 15.0 9.1 3.4 12.8 3.1 7.9 4.8 4.9 5.6 24.1 18.4 12.4 2.5 6.2 8.1 12.2 17.3 5.4 11.7 22.2 9.5 13.6 4.3 3.7 18.6 8.1 15.9 8.6 12.4 34.5 10.2 13.6 7.7 3.3 6.2 9.7 7.0 6.0 6.1 6.9 7.0 3.9 4.8 5.5 14.5 5.3 11.4 5.4 6.5 5.5 2.3 2.6 2.8 2.6 2.5 3.3 2.8 2.7 2.6 2.7 2.7 3.1 3.5 9.6 9.5 17.6 27.5 4.6 9.5 14.9 4.6 3.3 5.6 4.2 3.4 1.5 14.9 0.0 12.5 12.4 11.2 4.8 1.9 7.4 26.8 4.3 3.2 4.7 6.6 8.2 18.3 10.9 12.0 6.0 6.1 6.4 8.2 4.6 6.8 4.4 8.6 1.7 17.7 4.1 4.1 7.5 6.7 5.1 1.5 8.8 3.6 12.2 8.4 2.7 11.3 17.1 14.6 6.9 4.0 1.5 3.8 3.4 6.4 9.7 7.9 9.4 6.6 4.8 4.2 5.9 3.8 5.7 4.0 6.6 12.5 4.2 4.0 7.4 PIGN "MCD4, PIG-N" ENSG00000197563 "Phosphatidylinositol glycan anchor biosynthesis class N" O95427 18 61905255-62187118 "Disease related genes, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "GPI-anchor biosynthesis" Transferase "Disease variant, Epilepsy" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Alveolar cells type 1: 323.7;Alveolar cells type 2: 372.2;Club cells: 138.4;granulocytes: 159.0;Oligodendrocytes: 123.2;Respiratory ciliated cells: 145.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039922, HPA040374" Approved Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 6: Brain - Smell perception" "Cluster 16: U-266 - Nucleosome" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane, Cytosol" "HPA039922: AB_10805597, HPA040374: AB_10794738" "unprognostic (1.93e-2)" "unprognostic (1.71e-1)" "prognostic favorable (6.51e-4)" "unprognostic (1.03e-1)" "unprognostic (9.99e-2)" "unprognostic (3.99e-2)" "unprognostic (1.23e-1)" "unprognostic (3.99e-1)" "unprognostic (1.64e-2)" "unprognostic (1.75e-1)" "unprognostic (1.15e-1)" "unprognostic (2.81e-1)" "unprognostic (1.78e-1)" "unprognostic (6.59e-2)" "unprognostic (1.08e-1)" "unprognostic (5.75e-2)" "unprognostic (2.71e-1)" 10.0 10.3 9.8 10.9 14.3 16.9 15.9 49.4 47.1 11.8 3.2 16.2 14.0 11.1 11.9 22.7 8.9 12.6 13.5 13.1 9.6 11.9 18.1 9.9 10.5 4.1 0.1 12.1 15.8 16.0 4.3 17.5 9.6 17.3 18.4 38.9 14.8 7.5 13.4 20.1 13.3 8.9 0.0 10.0 21.1 19.8 11.4 12.3 16.9 10.8 12.8 14.9 7.7 49.7 31.6 19.0 18.4 23.0 23.1 31.4 24.3 32.3 25.7 21.2 24.9 24.4 31.9 36.0 44.0 25.0 18.3 44.6 26.0 27.8 32.9 30.3 16.9 21.6 29.6 19.7 16.8 46.0 24.6 18.5 18.1 21.0 24.5 22.3 27.0 25.3 26.1 50.8 23.3 28.2 22.8 13.5 29.9 25.3 17.3 24.1 35.1 35.7 25.5 48.5 20.8 21.4 42.5 29.0 13.6 50.9 46.1 28.6 29.8 41.0 28.2 15.4 23.5 54.3 53.8 17.4 22.5 25.7 40.9 10.1 7.5 6.1 6.9 6.6 7.2 7.9 7.1 6.9 8.9 8.8 8.0 8.4 9.6 12.1 7.8 10.2 6.5 3.7 9.8 14.3 49.4 47.1 13.1 9.6 4.1 0.1 9.6 0.0 11.4 49.7 8.9 323.7 372.2 52.5 9.7 8.0 8.9 8.4 10.2 7.2 16.3 9.4 10.4 12.8 138.4 11.0 4.2 9.6 14.1 11.6 1.9 11.0 6.4 9.1 16.2 24.7 6.7 16.6 54.5 9.5 11.5 26.6 10.2 11.5 159.0 19.3 10.0 12.0 10.1 6.7 41.3 11.6 10.2 9.2 4.0 6.5 7.2 26.9 3.6 44.0 7.9 7.3 3.1 57.8 123.2 10.9 9.4 3.8 8.2 11.7 5.6 5.0 145.5 6.6 6.6 6.8 6.7 20.7 7.3 17.4 17.0 10.4 18.5 10.5 12.3 12.1 PIK3CG ENSG00000105851 "Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma" P48736 7 106865278-106908980 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "Angiogenesis, Chemotaxis, Endocytosis, Immunity, Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 43.6;lymphoid tissue: 19.7" "Cell type enhanced" "Detected in some" "B-cells: 24.9;dendritic cells: 26.5;Early spermatids: 28.9;granulocytes: 20.8;monocytes: 23.8;NK-cells: 25.7;Plasma cells: 88.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "Daudi: 29.4;HL-60: 28.8;HMC-1: 34.9;Karpas-707: 29.1;MOLT-4: 56.0;U-266/70: 71.4;U-937: 52.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA069976 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 51: Monocytes - Innate immune response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 29: U-266 - Adaptive immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane" Cytosol "HPA069976: AB_2686224" "unprognostic (8.34e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (1.71e-2)" "unprognostic (3.20e-2)" "unprognostic (3.82e-3)" "unprognostic (3.02e-1)" "unprognostic (6.77e-2)" "unprognostic (1.16e-1)" "unprognostic (7.06e-3)" "unprognostic (1.15e-1)" "unprognostic (1.97e-1)" "unprognostic (1.77e-2)" "unprognostic (9.08e-2)" "unprognostic (1.23e-1)" "unprognostic (5.38e-1)" "unprognostic (5.24e-2)" 3.1 1.8 0.5 11.5 0.6 43.6 1.9 0.8 1.3 1.9 1.3 4.2 4.1 1.3 0.5 1.7 1.4 3.2 1.6 0.5 1.0 1.0 2.0 4.9 19.0 2.5 1.3 1.6 0.3 0.7 0.2 2.9 2.7 1.0 3.8 0.1 1.3 0.9 0.3 0.8 4.3 2.7 1.8 11.0 4.0 5.2 2.0 16.4 1.1 1.0 19.7 4.3 0.2 3.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 29.4 2.7 0.0 0.1 0.1 0.0 0.0 0.0 0.3 0.0 17.9 0.0 0.0 0.0 28.8 34.9 0.0 0.0 0.0 0.0 0.0 11.0 16.9 20.6 29.1 0.0 0.0 56.0 17.6 0.0 0.0 0.0 14.6 0.0 19.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 20.6 2.9 0.1 0.2 0.1 0.0 71.4 0.0 27.3 0.1 52.1 6.7 10.8 6.0 24.3 8.8 17.8 8.1 7.3 4.1 6.7 9.4 10.2 4.2 5.9 22.7 9.8 43.7 8.6 4.4 6.8 0.5 0.6 0.8 1.3 0.5 1.0 2.5 1.3 2.7 1.8 2.0 3.9 1.5 0.0 1.8 0.3 24.9 0.8 0.0 0.0 0.6 0.0 0.1 0.1 0.5 0.0 0.6 0.0 0.0 0.0 26.5 0.2 0.0 0.0 28.9 0.1 0.2 1.7 0.0 7.8 5.5 0.0 0.0 0.1 3.6 0.1 20.8 0.4 2.5 0.5 6.8 0.0 0.3 0.0 0.0 11.9 8.3 18.8 0.6 18.9 7.2 15.0 23.8 0.0 25.7 0.0 0.2 0.0 0.0 0.0 88.4 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.2 6.6 3.7 0.2 0.3 0.1 18.1 0.6 0.6 0.1 PIRT ENSG00000233670 "Phosphoinositide interacting regulator of transient receptor potential channels" P0C851 17 10822470-10838087 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "brain: 24.0" "Cell type enhanced" "Detected in single" "Astrocytes: 2.6" "Cancer enriched" "Detected in single" 40 "glioma: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA042337 Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 64: Astrocytes - Nervous system maintenance" Cytosol "Plasma membrane" "HPA042337: AB_10794795" "unprognostic (2.95e-1)" "unprognostic (2.19e-2)" "unprognostic (7.57e-2)" "unprognostic (6.58e-3)" "unprognostic (9.42e-2)" "unprognostic (2.05e-1)" "unprognostic (2.85e-3)" 0.0 2.5 7.5 1.1 8.7 0.0 0.0 11.5 6.8 0.0 1.7 4.0 1.0 0.0 0.0 0.1 0.2 0.1 0.0 5.4 11.6 0.0 0.0 0.0 0.0 22.4 16.5 0.0 0.0 0.0 0.0 0.0 14.0 0.1 2.6 0.2 0.0 0.0 0.0 0.3 1.9 0.8 11.8 0.0 1.4 0.0 24.0 0.0 0.0 0.0 0.0 0.0 0.5 10.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.5 8.7 11.5 6.8 5.4 11.6 22.4 16.5 14.0 11.8 24.0 10.8 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PKD2L2 TRPP5 ENSG00000078795 "Polycystin 2 like 2, transient receptor potential cation channel" Q9NZM6 5 137887968-137942747 "Predicted intracellular proteins, Predicted membrane proteins, Voltage-gated ion channels" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "testis: 8.2" "Group enriched" "Detected in many" 5 "Early spermatids: 42.7;Spermatocytes: 52.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HeLa: 2.2;Karpas-707: 2.6;U-266/70: 2.0" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA041903, HPA043634" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 21: Non-specific - Transcription" "Cluster 20: HeLa - Mitochondria" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Cytosol "HPA041903: AB_2677734, HPA043634: AB_2678591" "unprognostic (7.53e-3)" "unprognostic (2.21e-2)" "unprognostic (1.90e-1)" "unprognostic (3.59e-1)" "unprognostic (4.04e-1)" "unprognostic (1.21e-2)" "unprognostic (3.06e-1)" "unprognostic (1.40e-4)" "unprognostic (1.64e-2)" "unprognostic (2.13e-2)" "unprognostic (3.00e-2)" "unprognostic (5.85e-2)" "unprognostic (1.05e-3)" "unprognostic (2.21e-2)" "unprognostic (1.12e-1)" "unprognostic (1.28e-2)" "unprognostic (1.22e-1)" 0.4 0.9 1.5 0.5 1.7 1.5 0.2 3.2 1.1 0.2 0.3 0.1 0.3 0.3 0.7 0.4 0.3 0.4 1.1 0.8 1.2 0.2 0.1 0.2 0.9 0.7 0.5 0.3 0.8 0.1 0.3 0.2 0.8 0.4 0.2 1.1 0.5 0.0 2.3 0.5 0.2 0.1 0.1 0.7 0.4 8.2 1.1 0.1 0.7 0.8 0.2 0.1 0.2 3.1 0.7 0.5 0.1 0.0 0.1 0.2 0.7 0.2 0.0 0.0 0.0 0.0 1.4 1.0 1.5 0.0 0.0 0.3 0.0 0.0 0.0 0.7 0.4 0.6 2.2 0.0 0.0 0.1 0.6 0.0 0.0 0.0 0.0 0.3 0.2 1.4 0.7 2.6 0.0 0.2 0.5 1.0 0.2 0.0 0.4 0.0 0.0 0.0 0.0 1.0 0.4 0.4 0.6 0.1 0.4 0.3 0.2 0.2 0.2 0.4 0.7 0.2 0.5 2.0 1.6 0.1 1.0 0.2 0.8 5.3 0.9 1.8 1.0 0.6 0.5 1.5 0.8 0.7 0.5 1.9 1.0 0.9 4.1 1.0 0.6 2.0 0.6 0.6 1.5 1.7 3.2 1.1 0.8 1.2 0.7 0.5 0.8 0.1 1.1 3.1 0.6 3.2 2.2 4.6 4.7 2.2 1.8 0.6 7.4 2.4 0.5 0.4 1.7 0.0 0.9 0.0 0.0 0.4 1.6 0.6 0.0 0.1 42.7 1.5 1.3 1.3 0.0 0.8 5.0 0.0 0.2 1.5 0.5 1.8 1.3 0.5 1.4 0.4 0.3 3.3 5.6 0.0 2.0 0.6 1.9 8.2 0.6 1.3 3.6 1.9 0.1 0.9 1.0 3.5 6.1 0.1 0.0 0.4 1.7 1.5 0.1 0.3 0.0 4.1 0.0 3.2 1.1 52.3 3.1 2.6 1.1 0.1 3.1 0.8 0.2 0.8 PKN1 "DBK, MGC46204, PAK1, PKN, PRK1, PRKCL1" ENSG00000123143 "Protein kinase N1" Q16512 19 14433053-14471867 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" "Chromatin regulator, Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "NK-cells: 102.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003982, CAB010278" Approved Approved "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 39: Non-specific - Mitochondria" "Cluster 24: NB-4 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" "Cytokinetic bridge" "CAB010278: AB_2163965, HPA003982: AB_1855440" "unprognostic (3.83e-2)" "unprognostic (2.14e-1)" "unprognostic (4.13e-2)" "unprognostic (1.13e-2)" "unprognostic (1.94e-1)" "unprognostic (4.58e-1)" "unprognostic (1.30e-2)" "unprognostic (1.45e-1)" "unprognostic (1.43e-1)" "unprognostic (8.55e-3)" "unprognostic (4.08e-3)" "unprognostic (2.11e-1)" "unprognostic (1.45e-2)" "unprognostic (1.70e-1)" "unprognostic (8.66e-2)" "unprognostic (4.08e-1)" "unprognostic (2.24e-2)" 59.2 45.1 47.1 40.4 50.3 66.8 49.0 44.6 52.4 46.6 44.2 72.4 14.5 61.0 13.6 16.2 48.7 23.9 89.0 40.9 46.3 43.1 25.0 71.1 49.4 53.6 48.4 38.7 52.5 32.8 44.9 33.3 49.8 43.8 9.3 11.5 41.3 30.6 81.7 20.1 45.2 33.0 49.8 90.4 51.4 50.2 49.2 35.6 39.6 53.8 25.8 60.3 32.8 48.5 152.8 88.9 32.3 67.8 51.3 59.8 53.0 53.5 63.5 55.2 52.5 34.9 84.2 144.4 135.0 92.2 68.9 34.4 52.1 23.8 21.2 117.6 67.7 172.8 55.4 75.2 169.1 68.2 103.9 43.3 17.0 33.5 52.2 62.5 129.8 74.9 78.0 96.7 41.4 62.5 104.1 63.2 59.2 54.7 100.0 138.5 43.9 104.7 27.3 24.2 117.3 166.0 33.2 41.7 88.9 15.5 37.8 117.7 196.6 108.8 46.1 133.2 82.8 126.5 123.6 78.9 71.5 135.7 87.4 27.6 27.9 40.6 30.4 38.5 23.3 15.9 20.5 21.1 26.8 16.9 18.6 21.0 32.6 22.1 52.3 17.0 25.7 29.0 47.1 50.3 44.6 52.4 40.9 46.3 53.6 48.4 49.8 49.8 49.2 48.5 78.1 3.2 2.2 17.3 35.3 3.7 6.4 1.9 1.8 37.2 17.6 14.7 4.0 27.1 3.1 35.0 16.7 2.8 77.9 4.9 1.9 28.2 4.9 27.0 25.4 49.4 40.2 17.7 3.6 30.1 14.5 20.8 30.1 20.7 2.5 80.9 53.2 11.3 59.8 48.8 8.6 10.9 8.2 69.0 17.0 8.4 19.9 56.2 17.8 17.8 48.2 61.2 102.0 7.5 11.9 64.2 10.6 23.0 27.1 12.7 1.1 15.2 12.4 29.2 26.3 21.7 29.2 9.3 42.2 1.3 2.7 3.7 55.5 34.3 4.8 4.9 PKP1 B6P ENSG00000081277 "Plakophilin 1" Q13835 1 201283452-201332993 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Developmental protein" "Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "esophagus: 416.7;skin 1: 699.9;vagina: 200.4" "Group enriched" "Detected in many" 4 "Basal keratinocytes: 139.7;Squamous epithelial cells: 234.5;Suprabasal keratinocytes: 409.0" "Group enriched" "Detected in many" 4 "cervical cancer: 125.5;head and neck cancer: 295.4;lung cancer: 79.8" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "HaCaT: 234.6;HBEC3-KT: 144.2;hTCEpi: 501.4;hTERT-HME1: 132.5;PC-3: 192.6" "Not detected" "Not detected" "Low region specificity" "Detected in some" "HPA027221, CAB033130" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 2500000 "Cluster 31: Skin - Epidermis development" "Cluster 30: Epithelial cell lines - Translation" "Cluster 61: Squamous epithelial cells - Keratinization" "Nucleoplasm, Plasma membrane" "CAB033130: AB_2164139, HPA027221: AB_10599737" "unprognostic (3.55e-3)" "unprognostic (7.63e-2)" "unprognostic (1.99e-1)" "unprognostic (2.13e-1)" "unprognostic (1.03e-1)" "unprognostic (7.17e-2)" "unprognostic (2.40e-2)" "unprognostic (3.48e-2)" "unprognostic (1.49e-1)" "unprognostic (5.02e-2)" "unprognostic (2.20e-3)" "unprognostic (2.67e-1)" "unprognostic (9.17e-3)" "unprognostic (2.52e-2)" "unprognostic (1.61e-1)" "unprognostic (1.45e-1)" "unprognostic (6.59e-3)" 9.7 0.2 0.3 0.2 0.2 0.2 31.7 0.0 1.1 102.9 0.0 0.4 0.2 0.2 3.3 416.7 1.0 0.1 0.6 0.2 0.0 0.4 0.3 5.0 0.2 0.0 1.1 0.2 0.5 0.0 0.6 5.5 0.5 32.3 0.2 32.4 60.5 9.1 6.6 699.9 0.6 0.0 0.0 0.1 0.4 0.2 0.0 23.7 0.5 2.9 48.0 3.2 200.4 0.0 49.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 1.1 0.0 0.2 0.1 0.0 234.6 0.0 144.2 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.2 0.0 501.4 5.6 132.5 0.0 0.0 0.1 0.0 0.2 0.0 38.4 0.0 0.1 0.0 0.0 192.6 0.0 0.4 0.0 0.0 1.1 0.0 0.0 18.3 4.4 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 1.1 0.2 0.0 0.0 1.1 0.5 0.0 0.0 0.0 39.9 0.0 0.0 0.3 0.0 139.7 58.2 57.1 63.7 34.7 7.7 17.9 1.9 0.0 20.0 0.0 2.1 0.1 0.1 0.1 0.0 2.5 0.1 0.2 0.1 4.1 0.0 0.0 0.6 1.1 0.1 2.7 0.0 0.1 0.0 0.0 0.0 0.0 0.1 5.0 0.1 1.6 4.1 0.0 16.5 0.8 0.0 0.4 16.0 0.0 0.0 5.2 0.0 0.0 0.1 16.1 0.1 0.0 0.0 25.7 0.2 0.1 2.8 37.4 0.0 6.1 2.0 0.0 0.1 234.5 409.0 0.1 1.1 0.0 0.1 47.5 PKP4 p0071 ENSG00000144283 "Plakophilin 4" Q99569 2 158456952-158682879 "Plasma proteins, Predicted intracellular proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 256.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 261.0;Inhibitory neurons: 260.9;Oligodendrocyte precursor cells: 235.3;Oligodendrocytes: 864.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "non-classical monocyte: 2.0" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB037334, HPA066647, HPA070648" Approved Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 39: CACO-2 - Unknown function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Cell Junctions" "Plasma membrane" "CAB037334: , HPA066647: AB_2685696, HPA070648: AB_2686291" "unprognostic (2.76e-1)" "unprognostic (5.26e-2)" "unprognostic (1.48e-2)" "prognostic favorable (5.80e-4)" "unprognostic (2.34e-2)" "unprognostic (1.63e-1)" "unprognostic (1.02e-3)" "unprognostic (2.43e-1)" "unprognostic (1.04e-2)" "unprognostic (9.53e-2)" "unprognostic (1.82e-2)" "unprognostic (9.69e-2)" "prognostic favorable (3.29e-7)" "unprognostic (2.23e-1)" "unprognostic (9.80e-2)" "unprognostic (1.33e-3)" "unprognostic (2.28e-3)" 13.4 6.5 165.2 6.7 229.0 8.3 26.2 186.6 212.7 31.9 89.3 12.6 12.4 14.0 14.2 17.8 19.6 15.3 22.1 130.2 179.5 57.0 16.8 12.6 6.0 256.9 217.1 13.3 15.1 18.1 9.6 6.2 213.7 12.9 13.4 18.5 34.0 20.9 8.2 16.1 11.3 14.3 222.9 6.1 13.8 10.3 194.1 16.1 30.4 9.8 10.1 16.5 12.4 239.5 36.9 21.8 26.7 30.4 12.1 13.4 25.7 29.1 15.9 44.5 38.4 72.4 32.5 23.4 21.5 35.4 16.0 29.0 35.2 29.8 74.1 35.4 19.2 21.2 23.5 56.3 20.9 34.4 4.6 5.7 28.1 30.0 46.3 26.7 23.0 28.9 30.1 33.3 34.7 42.6 15.2 14.3 28.8 51.4 15.9 20.6 40.2 19.3 64.6 26.6 46.2 8.2 20.3 30.4 24.5 24.9 34.7 31.3 10.6 25.9 29.2 19.3 38.2 19.8 18.0 17.0 14.8 19.2 25.4 0.0 0.3 0.0 0.1 0.1 0.2 0.0 0.5 0.2 0.1 0.0 0.4 0.1 0.4 0.0 2.0 0.2 0.7 0.2 165.2 229.0 186.6 212.7 130.2 179.5 256.9 217.1 213.7 222.9 194.1 239.5 59.8 41.7 18.9 28.7 3.1 27.0 21.3 23.5 34.1 44.5 44.3 35.9 49.7 38.6 28.7 47.8 29.2 0.2 3.5 17.7 23.5 21.3 14.6 21.0 12.2 71.1 9.0 24.6 261.0 18.1 0.3 15.3 26.0 38.5 10.1 11.8 23.2 28.6 3.1 5.0 260.9 16.6 16.2 7.6 10.0 9.2 10.8 6.2 7.2 163.9 4.5 8.6 2.1 235.3 864.7 17.4 16.7 17.0 5.2 44.6 12.4 33.1 29.0 19.2 13.1 11.4 13.9 15.4 6.3 30.4 30.4 0.3 5.0 15.5 19.4 26.8 PLA2G4D cPLA2delta ENSG00000159337 "Phospholipase A2 group IVD" Q86XP0 15 42067009-42094562 "Enzymes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Lipid degradation, Lipid metabolism" Hydrolase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "prostate: 19.1;skin 1: 16.1;vagina: 22.5" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 2.1;Glandular and luminal cells: 1.1;Ionocytes: 2.0;Prostatic glandular cells: 3.0;Rod photoreceptor cells: 1.0;Suprabasal keratinocytes: 3.4" "Group enriched" "Detected in some" 4 "cervical cancer: 1.1;head and neck cancer: 2.0;melanoma: 1.8;prostate cancer: 1.3;urothelial cancer: 0.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 13 "RPMI-8226: 15.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA074206 Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 25: RPMI-8226 - Immune response" "Cluster 35: Glandular cells - Unknown function" Cytosol "Plasma membrane" "HPA074206: " "unprognostic (1.16e-1)" "unprognostic (1.10e-2)" "unprognostic (2.91e-2)" "unprognostic (9.16e-3)" "unprognostic (9.33e-3)" "unprognostic (4.35e-2)" "unprognostic (5.39e-2)" "unprognostic (2.37e-1)" "unprognostic (1.84e-1)" "unprognostic (1.28e-2)" "unprognostic (2.75e-1)" "unprognostic (2.64e-7)" "unprognostic (2.54e-2)" "unprognostic (2.34e-1)" "unprognostic (3.47e-2)" "unprognostic (4.32e-2)" 0.0 0.2 0.1 0.0 0.1 0.0 0.3 0.0 0.3 5.2 0.0 0.0 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.2 19.1 0.0 0.2 0.8 0.0 0.0 16.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.7 0.4 22.5 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.1 0.0 0.0 0.0 15.2 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.3 0.5 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.5 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 2.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.0 0.1 0.1 0.0 1.0 0.0 0.0 0.1 0.0 0.4 0.0 3.4 0.0 0.0 0.0 0.1 0.4 PLCB2 FLJ38135 ENSG00000137841 "Phospholipase C beta 2" Q00722 15 40278176-40307935 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Hydrolase, Transducer" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 52.4;lymphoid tissue: 40.7" "Cell type enhanced" "Detected in many" "dendritic cells: 22.6;granulocytes: 26.6;Hofbauer cells: 30.3;Kupffer cells: 46.6;Macrophages: 41.7;Microglial cells: 39.4;monocytes: 20.9;NK-cells: 26.8;T-cells: 20.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "HEL: 78.6;HMC-1: 93.4;THP-1: 28.1;U-937: 53.2" "Not detected" "Not detected" "Low region specificity" "Detected in many" "CAB009443, HPA041298, HPA068595, HPA069308" Enhanced Approved "Plasma membrane,Cytosol" NA NA 11000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "CAB009443: AB_632197, HPA041298: AB_2677395, HPA068595: , HPA069308: " "unprognostic (5.52e-2)" "unprognostic (4.96e-3)" "unprognostic (6.09e-3)" "unprognostic (1.88e-2)" "unprognostic (1.31e-1)" "prognostic favorable (3.00e-4)" "unprognostic (1.66e-1)" "unprognostic (3.08e-2)" "unprognostic (1.28e-1)" "unprognostic (2.34e-1)" "unprognostic (1.42e-1)" "unprognostic (2.75e-1)" "prognostic unfavorable (7.20e-5)" "unprognostic (9.89e-2)" "unprognostic (2.06e-3)" "unprognostic (5.81e-2)" "unprognostic (1.13e-1)" 5.9 4.0 3.8 29.2 3.9 52.4 2.5 3.8 5.4 3.3 3.4 5.1 6.1 2.7 1.4 3.0 4.5 9.7 3.0 4.0 5.6 1.9 6.3 16.8 28.7 8.4 7.1 1.5 1.3 1.3 2.1 7.0 7.3 2.6 8.0 0.5 5.4 4.0 1.2 1.9 10.4 7.3 6.2 40.7 5.5 1.3 7.7 20.5 2.2 1.7 22.2 7.3 1.8 9.6 0.4 0.0 0.6 0.0 0.0 0.0 10.5 0.0 0.1 0.0 0.0 0.1 19.1 1.5 17.6 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.2 78.6 0.0 0.0 0.0 16.9 93.4 0.0 0.0 0.0 0.0 0.0 0.1 10.2 0.7 4.3 0.0 0.0 4.7 9.2 0.9 0.0 0.2 13.7 2.0 0.1 0.1 0.0 0.3 0.3 0.0 0.0 0.2 5.1 0.0 28.1 10.1 0.0 9.1 0.0 0.0 0.0 0.0 3.7 0.0 53.2 0.0 1.7 2.6 5.3 1.8 2.7 1.2 0.4 0.9 0.9 2.7 0.5 0.9 1.0 4.2 1.2 2.7 1.0 1.9 1.5 3.8 3.9 3.8 5.4 4.0 5.6 8.4 7.1 7.3 6.2 7.7 9.6 0.9 6.4 16.8 0.3 9.6 0.9 0.1 0.1 0.6 0.1 1.9 2.5 3.3 1.5 3.2 1.8 0.0 0.5 22.6 0.2 0.0 0.1 2.2 0.2 0.5 1.7 0.0 8.0 1.8 0.0 0.5 1.9 0.0 0.2 26.6 0.1 1.1 0.4 30.3 0.0 0.8 1.7 0.0 46.6 15.5 0.6 0.3 41.7 3.6 39.4 20.9 0.0 26.8 0.5 0.2 0.4 0.3 0.0 5.7 0.0 0.0 0.9 4.4 0.2 0.0 0.4 0.7 0.5 2.3 0.3 0.6 0.4 20.8 0.3 2.0 0.0 PLPPR5 "LPPR5, PAP2, PAP2D, PRG5" ENSG00000117598 "Phospholipid phosphatase related 5" Q32ZL2 1 98890245-99005032 "Metabolic proteins, Predicted membrane proteins" Hydrolase "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Tissue enhanced" "Detected in some" "brain: 7.1;retina: 1.6;testis: 2.0" "Group enriched" "Detected in some" 4 "Bipolar cells: 8.5;Horizontal cells: 3.3;Spermatogonia: 6.9" "Group enriched" "Detected in some" 13 "glioma: 2.7;renal cancer: 1.5" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "PC-3: 11.9;SH-SY5Y: 21.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018072, HPA059085" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 65: Brain - Ion transport" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane" Cytosol "HPA018072: AB_1854958, HPA059085: AB_2732631" "unprognostic (2.57e-1)" "unprognostic (1.63e-2)" "unprognostic (1.68e-1)" "unprognostic (1.68e-2)" "unprognostic (2.01e-1)" "unprognostic (2.26e-1)" "unprognostic (1.11e-1)" "unprognostic (3.18e-1)" "unprognostic (1.43e-1)" "unprognostic (2.07e-1)" "prognostic unfavorable (6.22e-4)" "unprognostic (1.81e-2)" "unprognostic (1.28e-1)" "unprognostic (2.33e-1)" 0.0 0.4 5.2 0.0 5.8 0.0 0.0 0.1 6.6 0.3 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.1 4.5 0.0 0.0 0.0 0.0 1.3 3.9 0.0 0.4 0.0 0.2 0.0 2.8 0.0 0.1 1.6 0.0 0.1 0.1 0.0 0.0 0.0 2.0 0.0 0.0 2.0 7.1 0.0 0.0 0.0 0.0 0.2 0.0 3.5 0.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 0.0 11.9 0.0 0.0 0.0 0.5 0.1 0.4 21.6 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.1 0.2 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.2 5.8 0.1 6.6 6.1 4.5 1.3 3.9 2.8 2.0 7.1 3.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.2 1.5 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 0.0 0.0 0.0 0.0 0.0 3.3 0.0 0.0 0.0 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.5 0.0 0.7 0.0 0.0 0.0 0.6 0.0 1.3 0.0 0.1 0.1 0.0 6.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 PLS3 T-plastin ENSG00000102024 "Plastin 3" P13797 X 115561174-115650861 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 209.3;Alveolar cells type 1: 211.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 6 "NK-cell: 3.7;plasmacytoid DC: 12.2" "Group enriched" "Detected in many" 6 "dendritic cells: 12.2;NK-cells: 3.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020433, HPA076083" Approved Approved "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA020433: AB_2670440, HPA076083: AB_2686773" "unprognostic (1.32e-1)" "unprognostic (1.85e-2)" "unprognostic (6.10e-2)" "unprognostic (4.37e-2)" "unprognostic (9.63e-2)" "prognostic unfavorable (6.07e-5)" "unprognostic (2.40e-1)" "unprognostic (1.71e-1)" "unprognostic (1.83e-2)" "unprognostic (1.31e-1)" "prognostic unfavorable (4.59e-4)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (5.15e-2)" "unprognostic (1.54e-1)" "prognostic favorable (3.72e-4)" "prognostic unfavorable (7.04e-4)" 120.8 32.4 33.2 36.3 40.6 1.4 71.4 44.3 43.6 83.7 22.1 46.4 21.8 120.5 76.2 117.8 68.3 83.1 57.9 30.7 34.9 113.2 202.0 139.8 24.2 43.5 40.1 101.5 31.4 12.7 11.7 78.4 42.2 43.6 31.8 11.9 46.8 103.2 31.4 119.5 25.0 119.4 38.4 99.8 37.7 22.3 39.5 27.2 175.0 48.8 41.9 75.4 88.5 47.9 206.2 207.1 176.8 51.5 174.3 161.7 269.3 208.2 233.1 194.5 233.9 225.0 167.2 0.8 590.0 171.9 140.6 256.7 190.5 339.1 314.2 2.9 235.8 19.4 234.6 95.0 157.5 0.1 9.6 103.1 159.5 302.7 211.1 315.3 429.5 16.8 0.5 0.3 188.9 59.7 0.4 2.3 234.6 88.0 243.2 0.4 117.8 4.9 233.1 109.1 0.6 36.9 436.8 107.9 89.7 253.7 60.2 3.0 474.3 314.5 53.9 324.6 422.8 7.8 30.5 4.2 137.6 0.8 133.4 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.4 0.1 0.4 0.0 0.1 0.0 0.1 3.7 0.0 12.2 1.4 0.2 33.2 40.6 44.3 43.6 30.7 34.9 43.5 40.1 42.2 38.4 39.5 47.9 209.3 211.5 88.6 26.8 2.0 124.9 121.4 79.6 48.9 0.2 5.6 25.4 17.9 24.3 79.4 99.3 0.0 4.0 1.6 3.5 13.7 59.0 8.4 33.0 39.4 130.5 13.2 4.4 12.3 53.8 105.3 74.3 31.1 64.1 0.0 60.5 64.2 92.1 3.9 0.0 47.6 6.9 38.7 5.0 21.7 8.0 51.9 3.0 56.9 40.3 0.6 26.4 0.0 1.5 97.9 68.6 6.5 82.8 1.6 80.7 2.2 22.0 31.2 1.5 52.6 19.8 132.3 1.2 17.7 65.5 134.1 4.5 3.6 131.1 11.1 100.6 POLE POLE1 ENSG00000177084 "DNA polymerase epsilon, catalytic subunit" Q07864 12 132623753-132687376 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, DNA replication" "DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase" "Cancer-related genes, Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Spermatocytes: 46.6" "Low cancer specificity" "Detected in all" "Group enriched" "Detected in some" 4 "cerebellum: 4.1;cerebral cortex: 1.1;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in single" "Not detected" "Not detected" "HPA058210, HPA067385" Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 24: NB-4 - Immune response" "Cluster 12: Non-specific - Cell cycle regulation" Nucleoplasm "Plasma membrane" "HPA058210: AB_2683639, HPA067385: AB_2685830" "unprognostic (1.60e-1)" "unprognostic (1.77e-3)" "unprognostic (2.00e-1)" "unprognostic (9.17e-2)" "unprognostic (1.68e-1)" "unprognostic (2.01e-2)" "unprognostic (3.96e-3)" "unprognostic (2.23e-1)" "prognostic unfavorable (1.44e-4)" "unprognostic (7.12e-2)" "unprognostic (2.21e-1)" "unprognostic (1.67e-1)" "prognostic unfavorable (3.19e-8)" "unprognostic (8.60e-2)" "unprognostic (3.18e-1)" "unprognostic (1.28e-1)" "unprognostic (9.95e-2)" 6.0 2.9 0.2 6.1 0.2 24.7 6.0 4.1 1.1 6.4 0.3 7.3 6.5 5.4 2.1 7.0 6.2 3.1 4.3 1.6 0.0 3.0 8.6 5.0 7.2 0.3 0.1 7.8 6.5 2.6 2.7 5.3 0.3 6.4 6.3 2.4 6.1 3.3 7.5 13.2 8.5 3.7 0.1 16.2 8.0 16.2 0.5 15.7 4.7 3.0 7.1 6.1 6.2 0.3 25.3 33.3 48.7 22.0 10.2 7.6 39.9 26.0 11.7 30.3 21.8 38.3 14.5 28.7 10.2 14.1 11.6 33.6 35.4 16.7 18.8 13.3 41.2 45.4 45.7 15.2 1.9 37.2 24.9 5.5 6.0 31.8 10.5 8.1 10.8 35.1 53.4 15.7 14.9 33.3 61.8 46.8 36.9 9.3 18.5 48.0 27.6 13.0 6.9 40.8 40.6 22.0 30.0 22.7 4.7 23.4 35.0 19.1 9.9 26.5 24.7 20.6 25.9 20.3 14.5 44.8 14.7 26.3 19.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.2 0.2 4.1 1.1 1.6 0.0 0.3 0.1 0.3 0.1 0.5 0.3 3.2 0.0 6.7 7.5 4.0 5.7 3.8 3.0 4.0 8.7 7.8 6.7 6.9 1.5 1.6 1.8 0.0 8.8 5.6 18.8 0.0 2.3 8.2 3.2 3.8 4.9 7.2 14.9 13.6 3.3 10.8 5.1 11.2 6.8 2.5 16.2 8.9 10.5 13.2 0.0 7.6 9.1 2.0 6.9 5.4 9.7 6.8 2.9 5.4 4.7 1.6 2.6 2.1 3.5 2.9 2.6 6.0 3.4 6.3 4.0 4.1 1.0 1.9 6.1 26.3 7.0 6.1 46.6 18.2 5.8 7.7 4.0 5.8 2.9 10.9 2.8 PPEF1 "PPEF, PPP7CA" ENSG00000086717 "Protein phosphatase with EF-hand domain 1" O14829 X 18675909-18827921 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 5.8;testis: 14.6" "Group enriched" "Detected in some" 9 "Early spermatids: 64.0;Late spermatids: 139.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.1;HeLa: 1.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA034577 Uncertain "Plasma membrane,Cytokinetic bridge" Yes NA "Cluster 78: Testis - Spermatogenesis" "Cluster 20: HeLa - Mitochondria" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane" "Cytokinetic bridge" "HPA034577: AB_10602817" "unprognostic (4.13e-2)" "unprognostic (1.30e-1)" "unprognostic (9.06e-2)" "unprognostic (9.85e-2)" "unprognostic (3.84e-2)" "unprognostic (5.00e-2)" "unprognostic (2.38e-1)" "unprognostic (3.43e-2)" "unprognostic (4.96e-3)" "unprognostic (9.29e-2)" "unprognostic (1.70e-1)" "unprognostic (2.89e-1)" "unprognostic (1.10e-11)" "unprognostic (5.41e-3)" "unprognostic (2.75e-1)" "unprognostic (2.97e-2)" "unprognostic (1.19e-2)" 0.1 0.2 1.3 0.0 2.0 1.0 2.3 1.8 2.6 0.1 0.8 0.1 0.0 0.1 0.5 0.0 0.1 0.1 0.3 1.6 1.4 0.2 0.1 0.3 0.1 3.5 2.1 0.2 0.1 0.0 0.5 0.6 2.4 0.4 0.0 1.4 0.1 0.3 0.1 0.4 0.1 0.0 1.8 0.2 0.1 14.6 1.5 0.1 0.2 0.0 0.1 0.2 0.1 5.8 0.0 1.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.1 0.4 0.0 1.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.9 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 2.0 1.8 2.6 1.6 1.4 3.5 2.1 2.4 1.8 1.5 5.8 0.0 0.0 0.0 1.3 0.0 0.1 0.0 0.0 0.0 0.4 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 64.0 0.0 0.0 0.1 0.0 0.0 11.2 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 6.7 4.7 0.0 0.0 0.0 0.3 139.0 0.6 0.0 3.6 1.0 0.1 0.6 0.0 0.5 2.2 0.0 0.0 0.7 0.0 0.1 0.0 0.2 0.0 0.6 0.0 0.0 1.2 1.2 1.0 0.0 0.1 0.0 0.0 0.1 0.0 0.1 PPIP5K1 "HISPPD2A, IPS1, KIAA0377, VIP1" ENSG00000168781 "Diphosphoinositol pentakisphosphate kinase 1" Q6PFW1 15 43533462-43590253 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 41.7;Excitatory neurons: 46.6;Inhibitory neurons: 37.6;Rod photoreceptor cells: 44.2" "Low cancer specificity" "Detected in all" "Region enhanced" "Detected in many" "cerebellum: 45.4" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039380 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 21: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 9: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA039380: AB_10673528" "unprognostic (8.72e-2)" "unprognostic (6.49e-2)" "unprognostic (1.90e-2)" "unprognostic (1.12e-1)" "unprognostic (2.38e-1)" "unprognostic (2.78e-1)" "unprognostic (8.18e-2)" "unprognostic (5.78e-2)" "unprognostic (2.59e-3)" "prognostic unfavorable (8.57e-4)" "unprognostic (6.67e-2)" "unprognostic (2.85e-3)" "prognostic favorable (7.14e-8)" "unprognostic (2.67e-2)" "unprognostic (3.35e-2)" "unprognostic (5.92e-3)" "unprognostic (7.95e-3)" 6.6 14.8 5.7 7.3 9.8 5.9 10.3 45.4 21.0 8.3 1.1 17.6 24.7 7.4 15.1 11.6 9.4 8.3 7.5 8.0 1.8 8.5 5.6 5.8 7.8 6.0 0.6 9.2 9.4 33.7 21.6 4.5 8.8 10.0 17.6 53.7 13.8 8.3 20.0 20.0 24.3 7.7 0.0 8.6 15.5 15.5 2.8 5.4 14.3 21.2 10.0 9.0 9.9 9.2 14.5 9.3 8.1 15.0 4.8 3.0 13.8 7.1 9.0 10.0 14.6 11.0 13.5 13.5 10.5 9.8 14.9 38.6 15.8 30.6 10.1 13.3 12.5 20.3 29.9 5.9 11.0 23.4 20.2 5.4 26.6 12.2 18.6 13.5 10.7 31.0 15.0 19.4 7.4 11.3 7.8 13.2 3.9 27.0 10.0 16.7 8.2 6.8 10.7 25.9 24.1 7.6 18.3 17.2 6.7 11.4 31.7 19.4 4.7 8.7 10.2 11.1 17.4 4.3 5.7 16.4 16.3 26.5 8.5 2.4 0.5 0.0 1.0 1.1 1.3 2.0 1.2 1.3 1.2 1.2 0.9 0.9 0.3 1.5 0.8 0.9 0.3 1.3 5.7 9.8 45.4 21.0 8.0 1.8 6.0 0.6 8.8 0.0 2.8 9.2 2.3 0.0 2.2 11.4 5.2 4.0 1.5 3.2 7.4 16.5 3.2 3.3 5.4 2.8 3.4 7.3 41.7 3.3 2.9 9.2 0.0 2.1 2.7 2.1 1.4 2.9 2.4 5.5 46.6 1.5 0.9 1.8 20.9 2.8 0.0 9.5 3.3 1.8 1.9 10.1 37.6 5.9 0.0 2.8 1.8 2.4 1.8 2.1 0.0 15.0 1.8 3.9 0.0 11.6 11.0 1.9 5.2 7.2 3.1 1.2 12.2 1.5 2.3 44.2 6.6 2.3 3.2 8.1 3.3 7.3 3.3 2.2 3.1 3.5 8.2 3.2 PPM1A "MGC9201, PP2CA, PP2Calpha" ENSG00000100614 "Protein phosphatase, Mg2+/Mn2+ dependent 1A" P35813 14 60245752-60299087 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 142.9" "Cell type enhanced" "Detected in all" "Early spermatids: 446.2;Late spermatids: 565.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029209 Approved Supported "Plasma membrane,Cytosol" NA NA 380000 "Cluster 34: Basophils - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 51: Myeloid cells - Hemostasis" Cytosol "Plasma membrane" "HPA029209: AB_2672951" "unprognostic (3.14e-1)" "unprognostic (2.14e-1)" "unprognostic (5.64e-2)" "unprognostic (1.85e-1)" "unprognostic (4.00e-2)" "unprognostic (2.30e-2)" "unprognostic (4.50e-2)" "unprognostic (1.11e-1)" "unprognostic (3.43e-1)" "unprognostic (2.89e-2)" "unprognostic (7.96e-2)" "unprognostic (1.29e-1)" "prognostic favorable (1.57e-9)" "unprognostic (1.58e-2)" "unprognostic (1.12e-1)" "unprognostic (1.57e-2)" "unprognostic (1.37e-1)" 22.7 19.2 14.0 22.2 16.5 142.9 23.5 27.0 22.4 22.4 3.3 36.6 36.8 28.0 19.3 25.7 17.3 20.1 36.8 16.7 24.4 42.5 51.2 20.3 24.4 18.2 16.3 16.2 25.5 36.8 14.3 22.1 20.0 29.9 36.0 51.0 31.5 23.0 78.9 21.9 37.3 26.5 15.3 20.4 23.2 54.5 16.4 31.1 24.3 76.6 26.2 21.4 17.8 23.1 129.7 28.6 24.4 20.9 36.5 33.6 31.1 34.8 40.7 25.3 23.8 16.3 37.2 77.1 32.4 39.6 18.7 28.1 25.5 35.9 44.0 70.1 14.4 47.6 19.5 25.7 30.6 54.7 32.6 28.6 42.1 29.7 40.4 29.5 25.1 38.7 26.9 59.6 31.3 56.5 71.5 12.8 23.0 25.8 23.9 25.3 56.5 25.0 30.4 61.2 41.2 31.0 36.1 41.7 30.1 22.2 42.0 23.5 35.1 52.4 52.0 23.3 25.0 46.1 28.1 89.9 24.0 21.2 27.1 5.4 1.0 3.0 1.8 1.0 1.9 0.9 1.4 1.6 1.5 3.0 1.1 1.0 4.4 2.9 1.2 0.9 2.6 0.9 14.0 16.5 27.0 22.4 16.7 24.4 18.2 16.3 20.0 15.3 16.4 23.1 25.9 16.0 22.6 43.8 34.2 77.4 41.3 17.6 34.7 42.2 41.6 22.7 95.0 44.3 20.0 38.6 64.6 31.9 49.1 111.2 33.2 24.6 446.2 31.3 34.6 31.5 60.9 93.5 77.8 24.4 24.0 36.6 25.5 38.8 26.6 20.7 22.9 73.3 28.2 58.9 71.6 60.2 22.4 33.5 51.0 565.6 42.3 58.6 60.5 25.3 26.8 40.1 45.3 66.4 53.4 34.6 87.8 52.3 45.4 86.5 128.5 90.0 17.8 66.8 39.5 36.2 35.9 69.8 25.3 32.9 82.3 73.5 40.8 19.4 42.1 69.6 PPM1F "CAMKP, CaMKPase, FEM-2, KIAA0015, POPX2" ENSG00000100034 "Protein phosphatase, Mg2+/Mn2+ dependent 1F" P49593 22 21919425-21952848 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Endothelial cells: 42.2;Hepatic stellate cells: 56.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 28.6" "Group enriched" "Detected in all" 7 "dendritic cells: 8.9;granulocytes: 28.6;monocytes: 24.4" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 109.1;K-562: 173.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA030989, HPA030990" Approved Approved "Nucleoplasm,Plasma membrane" NA NA 510000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA030989: AB_10669549, HPA030990: AB_10601249" "unprognostic (6.26e-2)" "unprognostic (2.50e-1)" "unprognostic (1.82e-1)" "unprognostic (2.11e-1)" "unprognostic (2.51e-1)" "unprognostic (4.77e-3)" "unprognostic (4.88e-3)" "unprognostic (1.94e-1)" "unprognostic (1.70e-1)" "unprognostic (1.65e-2)" "unprognostic (1.45e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (6.03e-5)" "unprognostic (6.44e-2)" "unprognostic (3.02e-2)" "unprognostic (3.30e-1)" "unprognostic (4.11e-2)" 24.1 18.1 14.9 21.6 13.9 26.8 17.6 11.6 15.7 18.5 11.8 17.1 8.9 19.9 3.8 22.1 15.0 12.2 16.8 14.5 19.4 18.4 8.0 26.1 15.2 16.8 16.4 12.5 12.3 6.4 8.5 26.6 17.3 15.8 4.2 3.7 10.9 14.3 17.0 14.8 13.8 12.1 15.3 35.8 12.0 6.3 17.1 7.8 12.4 10.5 7.8 22.0 15.9 15.4 28.9 30.1 19.0 18.6 10.4 18.1 23.9 32.1 18.9 27.7 19.0 13.8 11.3 17.3 39.0 22.7 11.8 33.9 8.3 19.9 9.8 24.7 27.1 66.8 14.5 13.2 17.1 25.0 17.4 17.1 5.9 27.1 12.6 19.6 109.1 16.9 173.4 7.2 35.9 26.2 15.0 19.3 8.0 9.2 32.7 21.9 49.0 5.2 9.4 12.1 7.7 29.6 30.4 10.0 25.7 7.4 12.5 17.2 93.1 33.1 33.4 30.5 31.1 14.1 12.2 19.6 33.5 46.7 64.7 0.0 12.8 5.9 1.7 21.0 1.0 1.1 1.1 0.9 8.9 0.9 1.0 1.3 28.6 3.1 24.4 2.2 2.4 5.4 14.9 13.9 11.6 15.7 14.5 19.4 16.8 16.4 17.3 15.3 17.1 15.4 32.1 6.4 6.0 11.8 5.5 8.2 5.2 4.9 8.6 8.3 7.4 9.9 11.9 8.6 4.1 1.8 2.1 16.6 5.1 1.4 3.9 5.2 2.0 3.0 9.4 42.2 6.0 5.5 11.6 5.1 10.0 8.4 3.1 3.8 3.8 10.4 56.4 6.5 20.6 8.4 12.7 4.2 6.1 37.0 22.0 1.5 7.2 23.4 7.2 18.7 30.9 4.1 6.2 12.5 6.8 7.4 1.1 6.8 5.0 7.4 2.6 4.4 4.0 6.5 6.6 17.2 8.2 14.2 13.1 8.5 5.7 3.0 6.4 7.1 4.5 6.6 PPP1R12B "MGC131980, MGC87886, MYPT2, PP1bp55" ENSG00000077157 "Protein phosphatase 1 regulatory subunit 12B" O60237 1 202348699-202592706 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 356.9" "Cell type enhanced" "Detected in all" "Cardiomyocytes: 836.8;Excitatory neurons: 225.7;Granulosa cells: 438.3;Oligodendrocytes: 647.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 7 "neutrophil: 16.2" "Lineage enriched" "Detected in many" 7 "granulocytes: 16.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA024171, HPA024640" Enhanced Approved "Plasma membrane,Actin filaments" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Actin filaments" "HPA024171: AB_1854266, HPA024640: AB_1854265" "unprognostic (5.24e-2)" "unprognostic (8.59e-2)" "unprognostic (1.38e-1)" "unprognostic (2.75e-2)" "unprognostic (3.04e-1)" "unprognostic (5.45e-3)" "unprognostic (3.12e-2)" "unprognostic (9.13e-3)" "unprognostic (4.05e-2)" "unprognostic (3.74e-2)" "unprognostic (2.79e-2)" "unprognostic (1.80e-1)" "unprognostic (3.60e-3)" "unprognostic (6.98e-3)" "unprognostic (1.27e-1)" "unprognostic (1.28e-1)" "unprognostic (1.19e-1)" 40.0 11.1 5.1 36.0 12.6 8.3 17.8 8.9 9.9 51.8 15.5 151.0 24.1 222.0 30.5 150.1 52.6 72.5 356.9 5.5 6.5 14.3 8.4 24.8 18.6 17.2 15.3 38.3 7.2 6.2 5.0 34.4 18.0 142.8 64.8 7.6 20.0 198.6 84.1 11.0 30.9 246.4 16.2 30.8 41.5 7.1 9.2 7.7 10.9 80.5 15.1 86.7 23.0 27.3 2.2 4.4 3.3 3.2 4.6 3.3 5.4 1.7 1.7 1.8 1.7 1.9 3.9 2.5 0.8 3.2 4.3 7.0 5.0 2.7 1.9 3.3 3.1 2.5 7.1 1.2 1.1 5.4 2.8 2.6 3.0 2.5 2.6 9.1 1.5 2.8 3.9 2.9 3.1 1.7 4.1 3.4 2.3 2.4 0.9 2.6 8.5 3.7 1.4 8.1 4.0 3.1 3.3 3.9 1.9 4.4 3.4 2.4 1.9 2.5 1.5 1.9 1.5 4.2 4.3 2.7 2.4 4.4 10.2 2.4 1.7 1.5 1.6 1.0 1.4 2.0 1.1 1.0 1.5 2.1 1.3 1.0 16.2 0.7 1.5 1.7 1.7 0.5 5.1 12.6 8.9 9.9 5.5 6.5 17.2 15.3 18.0 16.2 9.2 27.3 12.5 12.8 19.8 181.5 6.0 17.3 49.0 35.6 8.6 59.3 11.1 20.6 836.8 11.5 23.0 12.9 75.0 18.1 8.6 52.9 11.7 10.1 39.2 19.3 16.1 15.2 24.0 5.2 225.7 12.9 8.4 51.4 17.3 7.6 18.9 438.3 16.4 9.6 9.4 26.9 205.0 17.2 63.1 23.5 10.9 13.1 12.2 8.2 8.8 102.1 7.8 10.2 5.2 102.5 647.4 6.3 21.1 51.1 9.6 24.3 12.8 7.1 27.4 30.4 32.9 38.6 162.7 19.3 13.9 7.1 10.9 25.4 10.7 14.2 33.9 28.4 PPP1R16B "ANKRD4, KIAA0823, TIMAP" ENSG00000101445 "Protein phosphatase 1 regulatory subunit 16B" Q96T49 20 38805697-38923024 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 71.6;lymphoid tissue: 41.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 119.4;Inhibitory neurons: 46.8;Oligodendrocyte precursor cells: 49.8;Oligodendrocytes: 238.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in some" "Daudi: 57.3;HMC-1: 59.2;HUVEC TERT2: 35.6;U-266/70: 96.7;U-266/84: 41.8;U-698: 38.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049571, HPA079512" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane" "Nuclear speckles" "HPA049571: , HPA079512: " "unprognostic (2.62e-2)" "prognostic favorable (2.11e-4)" "unprognostic (2.67e-3)" "unprognostic (3.35e-3)" "unprognostic (2.19e-1)" "prognostic favorable (7.87e-5)" "unprognostic (1.13e-1)" "unprognostic (4.17e-2)" "unprognostic (4.31e-2)" "unprognostic (6.28e-2)" "unprognostic (4.09e-3)" "unprognostic (4.77e-2)" "unprognostic (3.45e-2)" "unprognostic (8.53e-2)" "unprognostic (3.75e-2)" "unprognostic (1.73e-1)" "unprognostic (7.90e-2)" 13.2 2.9 36.5 19.3 71.6 17.7 8.2 26.1 61.1 3.2 5.1 4.6 3.6 3.4 1.5 3.1 5.8 5.3 5.2 49.3 22.3 27.7 2.4 7.9 37.7 27.8 34.7 1.1 1.5 0.8 2.2 3.7 27.1 1.6 5.1 3.7 2.0 1.9 3.6 1.5 18.0 7.2 24.3 18.1 5.6 0.7 35.7 18.2 3.4 5.7 41.9 6.0 1.6 52.1 0.1 0.7 9.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 57.3 0.8 0.0 0.9 0.1 1.0 0.1 0.0 1.4 0.2 4.4 0.0 0.0 0.0 0.2 59.2 0.0 0.1 0.0 0.0 0.0 35.6 7.6 1.0 11.9 0.0 0.0 7.4 9.7 7.9 0.1 0.0 5.0 0.0 0.0 0.0 0.0 17.7 19.7 0.0 0.0 0.0 0.7 0.0 3.1 5.5 0.0 0.9 0.0 0.0 96.7 41.8 38.3 0.0 0.0 0.1 0.0 0.2 2.5 3.4 0.5 1.8 5.3 2.3 3.3 0.7 3.3 1.3 1.8 0.0 2.9 0.9 3.3 2.6 1.1 36.5 71.6 26.1 61.1 49.3 22.3 27.8 34.7 27.1 24.3 35.7 52.1 29.3 3.2 3.0 1.3 33.6 1.0 0.0 0.8 0.6 2.3 0.5 0.5 23.5 1.5 4.0 0.0 0.0 0.0 34.0 0.3 0.0 0.0 1.9 0.2 0.2 18.7 0.0 2.7 119.4 0.0 0.0 1.6 4.1 0.3 3.8 0.0 38.6 0.3 0.1 37.0 46.8 0.1 0.0 3.1 3.6 1.5 0.0 3.8 8.8 23.4 20.5 0.3 11.3 49.8 238.0 0.0 0.1 0.0 29.3 0.0 0.0 17.4 3.6 0.3 0.0 0.3 1.0 0.0 0.3 0.3 1.3 0.0 37.4 0.0 0.2 0.3 PPP1R18 "KIAA1949, phostensin" ENSG00000146112 "Protein phosphatase 1 regulatory subunit 18" Q6NYC8 6 30676389-30687895 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hofbauer cells: 208.4;Kupffer cells: 164.4;Langerhans cells: 179.3;monocytes: 212.8;NK-cells: 332.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in all" 4 "eosinophil: 215.8;neutrophil: 169.6" "Lineage enriched" "Detected in all" 5 "granulocytes: 215.8" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA044745, HPA051000" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 11000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Nucleoplasm "HPA044745: AB_2679070, HPA051000: AB_2681304" "unprognostic (3.25e-2)" "unprognostic (1.19e-1)" "prognostic unfavorable (4.71e-4)" "unprognostic (1.01e-1)" "unprognostic (2.11e-2)" "unprognostic (1.59e-2)" "unprognostic (2.90e-2)" "unprognostic (3.37e-2)" "unprognostic (2.44e-1)" "unprognostic (1.18e-1)" "unprognostic (3.61e-2)" "unprognostic (2.40e-1)" "prognostic unfavorable (1.11e-16)" "unprognostic (1.73e-1)" "unprognostic (4.42e-2)" "unprognostic (9.33e-2)" "unprognostic (4.76e-2)" 35.4 16.7 9.5 42.5 9.1 56.0 25.9 9.9 12.8 30.2 7.0 38.0 8.8 36.8 3.5 18.1 28.6 25.6 23.2 9.4 12.1 14.2 16.8 51.5 75.5 17.8 12.6 26.8 10.1 2.7 7.0 21.4 15.5 19.7 7.7 2.6 15.4 11.5 10.8 21.6 33.7 17.3 13.7 80.4 19.5 5.9 15.6 53.5 17.6 9.0 38.2 36.1 24.4 13.9 63.2 9.4 34.4 37.3 28.0 80.4 1.7 48.4 63.6 43.3 29.9 6.6 11.2 64.7 25.0 77.3 73.7 35.8 21.6 44.7 29.6 74.8 2.2 79.3 20.7 6.6 59.1 28.6 116.3 44.0 44.0 97.9 89.8 64.5 60.0 53.3 27.2 58.2 57.8 6.9 40.8 43.5 3.2 1.6 13.8 162.8 28.8 33.9 18.0 3.4 3.8 19.2 30.1 10.9 65.9 18.8 9.4 26.8 90.8 139.4 29.2 29.4 103.3 11.6 57.3 77.3 40.7 131.9 155.9 43.0 16.4 215.8 43.4 21.8 31.8 20.9 23.1 42.5 9.5 22.0 16.7 32.5 169.6 37.8 25.2 14.9 39.7 22.6 9.5 9.1 9.9 12.8 9.4 12.1 17.8 12.6 15.5 13.7 15.6 13.9 39.1 3.2 15.7 1.6 89.7 109.0 29.6 15.7 79.6 2.3 14.2 14.6 3.1 8.6 4.6 9.2 0.0 3.1 116.5 0.8 0.0 25.1 24.2 4.4 24.4 67.8 1.8 35.4 0.8 8.2 20.4 34.1 7.1 6.7 53.2 5.9 32.9 8.2 208.4 3.3 1.3 0.8 8.2 164.4 179.3 19.9 27.7 123.3 39.2 19.7 212.8 1.0 332.7 11.1 0.1 20.8 0.0 23.3 52.9 23.8 0.4 2.5 4.4 3.1 26.3 28.6 53.5 1.2 1.3 38.3 59.7 4.0 141.6 6.8 0.7 22.5 PPP1R27 "DYSFIP1, toonin" ENSG00000182676 "Protein phosphatase 1 regulatory subunit 27" Q86WC6 17 81833492-81835050 "Predicted intracellular proteins" "Protein phosphatase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 25 "skeletal muscle: 1205.9" "Group enriched" "Detected in some" 14 "Early spermatids: 56.5;Skeletal myocytes: 108.8" "Cancer enriched" "Detected in single" 10 "head and neck cancer: 3.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 23 "HL-60: 206.4;THP-1: 385.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA042227, HPA048632" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 43: THP-1 - Innate immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA042227: , HPA048632: AB_2680469" "unprognostic (3.35e-2)" "unprognostic (1.12e-4)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (1.29e-1)" "unprognostic (1.85e-2)" "unprognostic (1.37e-1)" "unprognostic (2.21e-2)" "unprognostic (7.07e-2)" "unprognostic (1.32e-1)" "unprognostic (5.38e-2)" "unprognostic (8.70e-2)" "unprognostic (4.98e-6)" "unprognostic (7.97e-2)" "unprognostic (1.21e-1)" "unprognostic (2.19e-3)" "unprognostic (1.30e-1)" 0.3 0.9 0.0 0.0 0.1 1.3 0.4 0.2 0.3 0.4 0.0 0.2 0.0 0.1 0.0 1.2 0.1 0.0 0.5 0.1 0.0 0.2 0.7 0.2 0.0 0.1 0.0 0.2 0.4 0.0 11.8 0.0 0.1 1.8 0.0 0.0 5.8 0.0 1205.9 2.1 0.2 0.0 0.0 0.2 0.1 0.5 0.1 0.1 0.4 47.6 0.0 0.1 0.5 0.2 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 206.4 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 12.9 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 1.4 0.2 0.0 0.0 385.0 0.1 0.0 0.2 0.0 0.1 0.0 0.1 0.2 0.0 1.8 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.3 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.2 1.3 0.0 0.0 0.0 0.3 0.0 0.3 0.1 1.2 2.9 1.3 2.4 0.6 0.0 0.2 0.0 0.0 3.0 0.3 1.6 0.0 0.0 56.5 0.9 0.7 0.9 1.2 0.0 0.0 0.5 2.7 0.6 0.0 1.5 0.0 0.7 1.1 1.2 0.6 0.0 0.0 1.1 0.0 0.0 0.4 5.7 0.9 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.3 0.4 0.0 0.3 4.7 0.2 0.2 0.2 0.0 108.8 0.5 1.7 0.6 1.2 0.1 1.4 0.2 0.2 1.6 0.5 PPP2R1B "PP2A-Abeta, PR65B" ENSG00000137713 "Protein phosphatase 2 scaffold subunit Abeta" P30154 11 111726908-111766389 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 170.7" "Cell type enhanced" "Detected in all" "Early spermatids: 306.1;Late spermatids: 160.7;Spermatocytes: 135.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-698: 173.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004034, HPA018908" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 85: Liver - Metabolism" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "CAB004034: AB_490763, HPA018908: AB_1855655" "unprognostic (8.37e-2)" "unprognostic (3.87e-2)" "unprognostic (4.84e-3)" "unprognostic (3.27e-3)" "unprognostic (3.43e-1)" "unprognostic (4.93e-2)" "prognostic favorable (3.80e-4)" "unprognostic (4.58e-1)" "unprognostic (8.20e-3)" "unprognostic (2.26e-1)" "unprognostic (1.72e-1)" "unprognostic (8.41e-2)" "unprognostic (1.25e-3)" "unprognostic (1.25e-1)" "unprognostic (5.30e-1)" "unprognostic (2.12e-2)" "unprognostic (1.22e-1)" 58.5 10.5 11.3 14.1 18.0 16.2 21.5 20.0 13.9 13.0 17.3 14.7 13.9 8.7 8.1 12.6 8.0 13.4 6.3 11.7 13.8 14.6 170.7 8.8 12.1 14.7 13.7 13.3 33.2 12.9 10.7 9.2 14.2 7.7 14.7 8.5 9.6 6.1 9.6 10.7 15.2 7.8 10.6 6.3 22.3 54.0 13.8 15.9 10.6 8.9 14.1 12.2 7.4 20.7 38.4 25.1 35.6 24.2 34.9 18.7 35.8 37.2 25.9 27.0 24.6 86.0 39.3 48.3 27.1 24.1 25.6 35.4 53.4 30.5 34.3 33.7 16.6 47.2 14.5 37.8 17.3 55.7 36.1 21.5 18.1 30.6 22.2 19.1 33.8 49.7 58.3 62.3 30.1 12.4 60.8 22.6 43.8 41.4 27.3 45.9 23.6 58.6 40.2 41.9 11.6 31.4 33.1 30.2 6.1 38.3 35.0 20.6 36.7 31.3 37.8 15.6 23.9 6.6 17.4 173.8 11.1 63.9 40.7 6.1 10.1 10.4 13.0 11.7 12.7 10.0 12.9 12.1 14.9 12.5 11.2 12.0 2.6 15.3 11.4 6.4 15.0 12.2 11.3 18.0 20.0 13.9 11.7 13.8 14.7 13.7 14.2 10.6 13.8 20.7 21.2 19.2 10.5 63.3 11.0 14.3 11.0 12.0 18.2 5.4 14.1 8.5 3.2 15.7 13.4 12.9 8.4 13.5 11.0 23.8 13.7 18.7 306.1 29.6 13.4 20.2 15.6 32.4 23.8 22.9 20.3 12.3 15.3 46.1 8.2 34.3 9.3 89.4 9.5 1.7 14.5 11.5 22.4 5.8 9.2 160.7 6.5 7.5 8.8 17.8 8.9 9.9 7.2 26.2 49.1 23.6 9.0 7.5 9.0 10.9 16.2 17.6 16.8 11.0 13.1 14.5 14.4 135.9 20.8 12.0 14.6 17.6 11.0 9.7 13.9 15.0 PPP3R1 "CALNB1, CNB, CNB1" ENSG00000221823 "Protein phosphatase 3 regulatory subunit B, alpha" P63098 2 68178857-68256237 "Metabolic proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 189.9" "Cell type enhanced" "Detected in all" "Excitatory neurons: 151.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "neutrophil: 2.7" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB005610, HPA047157" Approved Supported "Plasma membrane,Cytosol" NA NA 42000 "Cluster 46: Basophils - DNA binding" "Cluster 58: Brain - Synaptic function" "Cluster 36: HEL - Hemostasis" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "CAB005610: AB_325975, HPA047157: AB_2679960" "unprognostic (2.12e-1)" "unprognostic (2.09e-2)" "unprognostic (1.55e-1)" "prognostic unfavorable (9.08e-6)" "unprognostic (5.90e-2)" "unprognostic (1.86e-1)" "prognostic unfavorable (5.37e-4)" "unprognostic (3.59e-1)" "unprognostic (3.96e-2)" "unprognostic (1.28e-1)" "unprognostic (1.13e-2)" "unprognostic (1.74e-1)" "prognostic unfavorable (1.70e-5)" "unprognostic (5.24e-3)" "unprognostic (5.35e-1)" "unprognostic (8.70e-2)" "unprognostic (1.24e-1)" 53.7 37.7 56.1 32.4 92.9 73.6 27.1 38.0 127.3 27.3 0.0 27.6 25.7 31.0 26.1 30.0 23.3 28.0 20.6 99.0 24.2 21.4 58.2 27.7 40.2 23.5 18.4 24.9 20.7 17.0 18.3 36.6 24.9 26.3 27.8 189.9 24.9 30.1 88.8 33.6 23.9 35.3 14.4 34.2 24.8 20.6 30.0 42.6 23.8 31.0 40.5 32.9 28.6 64.5 61.5 51.7 69.7 48.4 47.4 54.3 70.5 86.3 75.9 98.8 86.8 75.9 55.4 85.7 28.7 61.4 69.5 41.8 74.4 64.8 120.0 59.4 52.9 284.0 38.3 71.1 93.1 111.9 92.2 55.1 57.6 76.9 78.0 55.9 67.2 72.2 67.8 96.8 73.2 53.8 96.1 99.4 81.9 52.0 44.4 69.1 90.6 139.9 61.7 66.1 91.4 64.2 50.4 72.3 65.9 45.0 33.9 51.8 69.5 84.6 76.5 64.2 75.1 53.8 62.6 124.7 61.3 115.2 54.0 1.5 0.5 1.3 0.2 0.3 0.5 0.2 0.3 0.1 0.5 0.3 0.3 0.5 2.7 0.3 0.6 0.7 0.3 0.4 56.1 92.9 38.0 127.3 99.0 24.2 23.5 18.4 24.9 14.4 30.0 64.5 37.0 9.6 12.7 81.6 40.4 74.8 11.6 7.0 72.8 22.2 21.0 13.1 17.9 10.0 7.7 16.5 52.1 11.7 34.0 20.5 11.7 7.1 20.0 19.9 23.0 34.0 15.1 52.8 151.2 8.7 17.2 24.2 18.8 29.1 19.7 11.2 15.4 19.2 24.7 11.8 93.1 15.6 4.1 40.0 105.1 7.7 9.9 54.7 35.6 105.9 21.2 27.8 18.6 72.9 77.5 12.9 10.6 8.6 39.2 17.3 12.6 20.1 5.8 92.7 13.1 14.4 29.8 2.9 6.1 64.0 70.5 12.0 39.9 14.2 13.2 21.3 PPP3R2 PPP3RL ENSG00000188386 "Protein phosphatase 3 regulatory subunit B, beta" Q96LZ3 9 101591604-101595021 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 161 "testis: 80.8" "Group enriched" "Detected in some" 38 "Early spermatids: 399.2;Late spermatids: 198.3;Spermatocytes: 600.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA047157 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Cytosol "HPA047157: AB_2679960" "unprognostic (8.81e-2)" "unprognostic (2.65e-1)" 0.0 0.0 0.3 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 80.8 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.0 0.5 0.1 0.0 0.4 0.1 0.4 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 399.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 198.3 10.5 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.2 0.0 0.0 0.0 0.0 0.0 0.0 6.6 0.1 0.2 600.6 3.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 PPTC7 TA-PP2C ENSG00000196850 "Protein phosphatase targeting COQ7" Q8NI37 12 110533245-110583318 "Enzymes, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "tongue: 140.0" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039335, HPA040614" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "HPA039335: AB_10805474, HPA040614: AB_10795526" "unprognostic (2.44e-1)" "unprognostic (2.38e-2)" "unprognostic (1.11e-1)" "unprognostic (9.44e-2)" "unprognostic (2.38e-1)" "unprognostic (3.46e-2)" "unprognostic (2.14e-1)" "unprognostic (3.51e-2)" "unprognostic (1.47e-2)" "prognostic unfavorable (1.43e-5)" "prognostic unfavorable (6.76e-4)" "unprognostic (1.09e-1)" "prognostic favorable (4.48e-5)" "unprognostic (5.34e-2)" "unprognostic (2.83e-1)" "unprognostic (5.01e-3)" "unprognostic (1.83e-1)" 18.8 25.5 6.9 16.1 7.3 52.3 13.4 12.1 11.1 15.5 8.3 15.7 13.4 14.3 6.4 21.6 11.3 15.0 40.0 6.5 14.1 21.5 21.0 15.6 20.7 12.7 12.4 13.1 13.2 30.6 8.4 10.7 12.1 12.3 16.7 15.6 17.8 13.4 88.7 21.5 13.2 16.1 9.2 15.2 11.9 14.0 13.0 18.4 11.6 140.0 18.4 19.0 19.1 7.4 24.3 13.6 11.4 12.0 27.8 24.3 16.3 10.9 14.3 11.7 11.7 15.4 9.3 42.2 11.1 10.8 16.7 23.0 23.1 25.3 23.5 30.9 19.1 37.5 14.4 16.7 26.3 41.8 29.6 21.0 40.7 16.6 48.4 17.4 22.5 28.8 28.3 11.7 19.2 6.3 37.2 35.7 16.1 13.0 25.0 30.7 15.3 25.8 48.7 26.7 18.4 14.2 20.6 28.2 24.4 11.0 13.4 22.1 25.9 10.7 11.5 32.8 18.6 33.5 40.0 46.7 18.0 22.6 21.4 0.0 0.6 0.5 0.8 0.5 0.8 0.4 0.6 0.6 0.4 0.7 0.7 0.6 2.1 0.6 0.4 0.5 0.5 0.2 6.9 7.3 12.1 11.1 6.5 14.1 12.7 12.4 12.1 9.2 13.0 7.4 14.1 22.4 28.3 16.0 35.7 91.9 53.1 33.9 56.9 8.6 20.2 12.8 105.4 12.8 36.0 9.2 14.6 7.5 28.2 36.7 17.6 7.7 29.7 34.4 20.4 22.3 16.8 7.8 15.5 8.2 8.4 26.1 12.8 63.3 23.5 8.6 15.4 29.5 17.4 13.5 19.8 15.2 30.5 28.3 97.6 33.2 11.5 30.8 33.8 21.5 31.9 4.8 20.6 19.1 11.7 14.6 15.1 9.8 28.2 57.3 16.5 13.1 35.4 23.8 13.1 22.8 22.4 15.9 24.1 57.1 104.3 6.7 28.7 8.2 17.2 77.5 PRAME "CT130, MAPE" ENSG00000185686 "PRAME nuclear receptor transcriptional regulator" P78395 22 22547701-22559361 "Plasma proteins, Predicted intracellular proteins" "Apoptosis, Differentiation, Growth regulation, Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 105.1" "Cell type enriched" "Detected in some" 4 "Spermatogonia: 249.0" "Cancer enhanced" "Detected in many" "melanoma: 139.6" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in many" 5 "K-562: 834.1" "Not detected" "Not detected" "HPA045153, HPA068562" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA045153: AB_10797259, HPA068562: " "unprognostic (9.36e-3)" "unprognostic (9.74e-2)" "unprognostic (1.02e-1)" "unprognostic (3.87e-2)" "unprognostic (5.20e-2)" "prognostic unfavorable (3.41e-4)" "unprognostic (3.43e-2)" "unprognostic (4.00e-2)" "unprognostic (1.33e-1)" "unprognostic (6.52e-3)" "unprognostic (9.68e-3)" "unprognostic (2.06e-1)" "prognostic unfavorable (7.48e-9)" "unprognostic (1.95e-1)" "unprognostic (2.21e-1)" "unprognostic (8.87e-2)" "unprognostic (1.26e-1)" 0.2 3.7 0.0 0.2 0.0 0.0 0.1 0.0 0.0 1.4 0.0 0.2 0.0 3.4 10.0 0.0 0.5 0.0 0.3 0.0 0.1 1.8 0.1 0.2 0.1 0.1 0.0 4.7 0.1 0.0 0.3 0.0 0.1 0.1 0.0 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.0 0.1 0.1 105.1 0.0 0.2 0.1 0.0 0.1 0.0 0.2 0.2 0.9 53.3 0.0 126.0 0.0 0.0 33.4 0.0 0.0 0.0 0.0 0.4 0.7 3.5 88.8 0.0 0.5 0.1 4.3 0.0 0.0 61.5 14.8 36.0 21.7 0.6 0.0 2.9 172.6 0.0 0.0 0.0 0.0 0.0 0.0 14.9 834.1 15.6 0.0 8.1 0.3 0.2 0.0 27.2 3.5 5.0 0.0 0.2 0.0 0.2 1.1 185.0 0.0 0.6 0.2 0.0 27.8 24.3 5.0 0.1 159.6 0.0 0.2 3.0 14.6 1.3 0.2 0.8 19.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 37.8 22.3 1.1 0.3 0.0 0.0 0.0 0.0 0.9 2.0 0.0 13.0 0.0 60.9 0.0 0.0 0.1 10.1 0.0 0.0 0.0 0.0 0.0 41.4 5.6 0.4 0.0 0.0 3.1 0.2 0.0 0.0 0.0 0.1 0.0 3.4 0.0 0.0 0.0 1.8 0.0 0.4 6.6 0.0 2.7 41.8 249.0 0.0 0.0 0.0 0.1 14.2 0.1 0.0 PRDX6 "1-Cys, aiPLA2, AOP2, KIAA0106, MGC46173, NSGPx, p29, PRX" ENSG00000117592 "Peroxiredoxin 6" P30041 1 173477330-173488815 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Lipid degradation, Lipid metabolism" "Antioxidant, Hydrolase, Multifunctional enzyme, Oxidoreductase, Peroxidase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Distal enterocytes: 1315.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006983, CAB008663" Supported Supported "Plasma membrane,Cytosol" NA NA 120000000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 39: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane, Cytosol" "CAB008663: AB_1620994, HPA006983: AB_1079595" "unprognostic (9.92e-2)" "unprognostic (1.50e-1)" "unprognostic (3.67e-1)" "unprognostic (2.99e-3)" "unprognostic (1.96e-1)" "prognostic unfavorable (1.23e-5)" "unprognostic (5.71e-3)" "unprognostic (2.80e-2)" "unprognostic (5.27e-3)" "unprognostic (3.96e-3)" "unprognostic (3.19e-3)" "unprognostic (1.59e-1)" "prognostic unfavorable (9.51e-4)" "unprognostic (2.50e-1)" "unprognostic (7.12e-2)" "unprognostic (1.15e-1)" "unprognostic (4.73e-3)" 340.7 157.5 169.5 68.3 181.3 100.1 211.2 197.6 210.1 112.3 164.8 189.1 46.4 108.8 206.3 127.9 149.8 71.9 261.8 184.1 196.6 184.4 482.5 116.7 72.2 181.0 198.3 115.5 114.4 217.5 67.4 70.7 187.5 152.1 221.6 53.9 85.6 99.0 563.5 106.6 59.8 160.2 175.8 70.7 135.2 119.1 176.7 70.7 106.0 382.4 79.0 99.5 109.8 185.5 420.3 127.7 204.7 230.9 778.5 372.7 169.5 843.9 284.3 342.7 241.8 243.9 276.4 272.4 256.4 694.2 120.4 239.8 272.0 259.9 279.0 234.0 243.6 179.5 200.0 277.7 425.7 191.3 56.1 301.0 262.6 181.3 256.6 210.8 339.5 106.7 405.4 52.8 392.9 86.3 131.7 249.1 456.2 219.8 760.5 154.5 236.6 277.0 518.1 95.4 94.9 173.4 285.0 334.0 199.2 296.3 283.8 262.9 228.2 132.5 149.9 201.8 229.5 76.4 123.2 220.7 159.4 162.3 124.3 36.2 42.5 24.8 29.8 39.8 32.8 32.6 29.8 38.4 53.5 24.4 39.8 47.9 25.2 25.7 36.5 79.7 36.1 58.1 169.5 181.3 197.6 210.1 184.1 196.6 181.0 198.3 187.5 175.8 176.7 185.5 278.1 176.3 170.8 127.3 127.4 235.4 404.1 382.8 209.5 31.9 186.1 250.7 528.6 301.7 228.6 277.7 29.2 714.3 158.6 1315.9 860.8 178.6 237.5 206.9 226.8 191.8 142.1 449.5 13.8 202.3 939.1 307.0 111.6 200.0 348.6 216.6 214.2 1120.2 345.0 45.4 13.2 257.4 205.4 164.3 161.0 667.5 340.5 227.1 183.2 17.8 212.9 462.5 83.4 12.5 15.4 147.2 663.4 416.8 176.4 427.1 264.4 827.3 209.1 52.0 184.1 185.7 253.8 123.5 76.8 305.9 264.1 963.5 157.7 512.5 303.6 308.9 PRKCA "PKCA, PKCα" ENSG00000154229 "Protein kinase C alpha" P17252 17 66302613-66810743 "Cancer-related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "Angiogenesis, Apoptosis, Cell adhesion" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 76.8" "Cell type enhanced" "Detected in many" "Astrocytes: 564.8;Excitatory neurons: 247.6;Inhibitory neurons: 400.0;Microglial cells: 281.1;Oligodendrocyte precursor cells: 849.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 157.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003844, HPA006563, HPA006564, CAB016290" Enhanced Approved Enhanced "Plasma membrane,Cytosol" NA NA 190000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 68: Oligodendrocytes - Mixed function" Cytosol "Plasma membrane" "CAB003844: AB_562331, CAB016290: AB_628141, HPA006563: AB_1079626, HPA006564: AB_1079625" "unprognostic (3.06e-1)" "unprognostic (3.56e-2)" "unprognostic (1.38e-2)" "unprognostic (1.01e-1)" "unprognostic (1.53e-1)" "unprognostic (7.41e-3)" "unprognostic (7.43e-2)" "unprognostic (6.86e-3)" "unprognostic (4.93e-2)" "unprognostic (1.50e-1)" "unprognostic (2.09e-1)" "unprognostic (2.24e-2)" "unprognostic (5.50e-2)" "unprognostic (2.46e-1)" "unprognostic (1.83e-1)" "unprognostic (1.35e-3)" "unprognostic (8.77e-2)" 3.1 21.1 37.0 6.9 35.0 1.8 2.3 20.8 51.4 7.5 11.8 18.5 11.9 11.7 4.8 3.2 4.6 7.5 4.4 76.8 32.8 12.8 7.3 4.5 4.9 37.3 36.1 15.7 5.1 0.9 6.3 5.0 25.3 13.0 8.6 30.1 2.3 16.9 5.8 3.0 10.6 10.7 30.1 6.5 8.4 2.6 36.9 3.1 3.2 4.3 4.6 8.9 5.6 27.3 7.3 38.0 7.7 7.8 18.2 46.0 1.0 40.8 26.4 28.8 24.3 4.5 4.6 9.6 10.9 65.9 48.1 0.9 3.9 4.8 61.9 16.4 9.3 0.0 22.2 20.2 24.9 12.2 62.8 20.2 1.8 36.0 30.5 41.8 25.0 45.6 25.8 0.2 44.8 2.3 24.9 7.4 3.1 18.9 20.2 4.5 56.5 0.2 10.2 6.4 4.6 25.6 13.5 7.7 0.4 8.0 0.8 17.0 75.1 49.6 28.6 31.4 25.8 0.1 0.0 1.2 157.6 0.1 25.1 0.0 0.2 0.0 0.1 0.2 0.5 0.0 0.8 0.4 0.3 0.0 1.2 0.7 0.0 0.0 1.1 0.4 0.1 0.3 37.0 35.0 20.8 51.4 76.8 32.8 37.3 36.1 25.3 30.1 36.9 27.3 10.0 0.0 8.4 564.8 5.7 10.6 15.0 10.3 13.6 198.3 7.9 11.2 9.8 45.8 7.2 40.5 2.1 4.1 24.6 27.1 7.9 16.1 3.2 5.5 40.1 5.6 8.4 5.7 247.6 6.8 3.4 17.5 23.9 6.3 20.3 39.9 27.8 14.7 25.4 10.1 400.0 38.4 2.0 11.9 7.6 3.0 53.4 20.9 10.6 281.1 6.8 34.3 12.3 849.0 198.3 8.8 21.0 48.5 11.8 12.8 27.0 21.3 7.0 77.1 26.3 6.5 41.4 1.3 3.9 6.1 10.4 15.2 36.9 47.1 26.4 17.2 PRKCH "PKC-L, PKCL, PRKCL" ENSG00000027075 "Protein kinase C eta" P24723 14 61187559-61550976 "Cancer-related genes, Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" Differentiation "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 128.4;Microglial cells: 267.9;NK-cells: 229.6;T-cells: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 11 "gdT-cell: 116.5;MAIT T-cell: 91.3;memory CD4 T-cell: 88.0;memory CD8 T-cell: 137.0;naive CD4 T-cell: 106.9;naive CD8 T-cell: 105.5;NK-cell: 117.1;T-reg: 79.8" "Group enriched" "Detected in all" 14 "NK-cells: 117.1;T-cells: 137.0" "Cell line enhanced" "Detected in many" "BEWO: 81.8;HUVEC TERT2: 108.7;MOLT-4: 75.8;RT4: 46.4;TIME: 72.0" "Group enriched" "Detected in all" 6 "basal ganglia: 28.0;thalamus: 17.9" "Low region specificity" "Detected in all" "HPA026294, HPA053709" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA026294: AB_10603988, HPA053709: AB_2682237" "unprognostic (1.42e-1)" "unprognostic (3.89e-3)" "unprognostic (1.78e-1)" "unprognostic (1.96e-3)" "unprognostic (1.04e-1)" "prognostic favorable (8.55e-6)" "unprognostic (1.14e-2)" "unprognostic (2.97e-2)" "unprognostic (4.14e-1)" "unprognostic (1.94e-1)" "unprognostic (7.96e-2)" "unprognostic (1.60e-1)" "unprognostic (1.52e-3)" "unprognostic (1.13e-1)" "unprognostic (4.14e-2)" "unprognostic (6.98e-2)" "unprognostic (4.73e-3)" 26.6 7.8 21.1 21.9 30.2 24.2 21.9 12.4 15.7 20.6 9.5 8.9 9.5 14.5 10.9 30.0 13.6 19.7 19.2 13.2 13.9 14.5 10.3 35.3 55.2 19.3 21.7 5.9 8.4 14.2 15.0 32.5 19.4 15.8 8.8 3.1 28.3 11.4 14.2 23.7 16.6 18.1 18.6 38.5 9.6 7.5 29.9 65.8 21.1 18.1 38.5 25.3 21.7 15.5 18.1 6.3 0.8 4.9 2.8 0.6 81.8 0.3 1.5 0.8 0.8 1.9 10.5 0.3 12.4 0.1 1.6 12.3 0.6 13.5 1.4 2.2 7.9 0.1 2.0 0.7 1.2 0.0 2.4 2.2 13.8 0.7 9.4 1.2 108.7 35.4 0.2 0.4 6.2 32.7 75.8 0.7 1.4 12.9 8.4 6.3 3.2 0.2 0.2 46.4 3.2 5.1 2.1 16.2 10.2 14.5 15.9 1.4 72.0 2.1 14.0 2.1 0.9 1.4 0.2 0.6 3.1 1.1 3.6 0.8 3.0 2.4 116.5 1.9 91.3 2.2 88.0 137.0 9.2 1.4 106.9 105.5 5.9 117.1 1.1 3.0 79.8 84.0 21.1 30.2 12.4 15.7 13.2 13.9 19.3 21.7 19.4 18.6 29.9 15.5 59.7 6.4 11.4 2.0 6.6 18.7 16.4 8.3 15.9 0.4 15.0 9.3 9.0 10.0 15.5 0.0 0.0 27.6 128.4 0.6 3.9 6.0 32.6 10.3 2.1 70.8 11.9 18.1 1.7 6.8 21.2 5.0 7.1 20.9 1.3 15.4 68.9 2.0 6.0 0.0 3.1 2.7 2.0 14.4 6.9 6.0 1.8 15.4 16.0 267.9 8.9 7.0 229.6 4.5 1.8 5.4 4.3 6.8 26.6 14.7 4.6 1.2 9.2 0.5 0.0 4.4 5.2 0.1 2.4 18.1 26.7 48.3 130.5 1.6 1.3 26.0 PRKCZ PKC2 ENSG00000067606 "Protein kinase C zeta" Q05513 1 2050411-2185395 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Inflammatory response" "Kinase, Serine/threonine-protein kinase, Transferase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 58.0" "Group enriched" "Detected in many" 4 "Late spermatids: 708.3;Syncytiotrophoblasts: 1107.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 6 "eosinophil: 16.3" "Lineage enriched" "Detected in many" 6 "granulocytes: 16.3" "Cell line enhanced" "Detected in many" "BEWO: 44.5;OE19: 41.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021851 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 6: Brain - Smell perception" "Cluster 28: BEWO - Transcription regulation" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" Cytosol "Plasma membrane" "HPA021851: AB_1855433" "unprognostic (1.25e-2)" "unprognostic (2.61e-1)" "unprognostic (5.10e-2)" "unprognostic (1.14e-2)" "unprognostic (2.08e-1)" "unprognostic (3.61e-2)" "unprognostic (1.73e-2)" "unprognostic (5.13e-2)" "unprognostic (1.18e-1)" "unprognostic (3.10e-1)" "unprognostic (1.12e-1)" "unprognostic (2.86e-1)" "prognostic favorable (1.64e-9)" "unprognostic (3.57e-2)" "unprognostic (3.27e-2)" "unprognostic (1.39e-1)" "unprognostic (7.85e-2)" 1.7 11.1 23.6 4.6 25.7 2.1 5.6 58.0 41.3 4.3 0.0 13.2 29.3 2.2 7.8 16.0 9.5 4.4 9.7 23.7 10.2 16.0 11.0 31.6 8.0 18.6 8.3 2.7 12.5 14.7 17.6 43.8 19.0 8.4 11.3 14.8 10.8 3.9 0.3 13.8 28.0 1.6 5.6 10.5 8.9 31.9 7.2 3.7 21.8 0.6 7.8 5.8 8.0 24.8 14.7 9.7 3.4 17.2 0.0 0.0 44.5 1.2 0.5 11.1 0.7 23.8 31.0 0.1 27.4 3.9 9.4 25.4 20.5 25.5 7.9 1.0 21.8 0.0 15.2 33.5 3.2 0.1 11.0 0.6 14.9 0.0 8.6 0.0 0.0 4.0 6.6 0.2 0.2 17.9 0.9 0.0 6.4 41.9 22.5 0.0 0.0 5.1 18.6 16.0 24.1 18.7 11.6 27.5 5.2 28.7 17.7 4.0 0.0 0.1 13.1 0.1 0.1 6.8 1.3 0.3 1.2 0.3 16.8 0.3 0.0 16.3 0.5 0.3 2.5 0.3 0.9 0.6 0.0 0.4 0.8 0.3 1.1 0.9 0.0 0.3 0.9 0.3 23.6 25.7 58.0 41.3 23.7 10.2 18.6 8.3 19.0 5.6 7.2 24.8 0.9 121.8 72.2 2.3 6.5 13.0 11.8 11.0 10.2 27.1 11.3 11.0 1.4 5.7 21.1 7.3 4.2 118.7 7.5 48.9 7.9 12.3 224.4 14.0 4.7 6.3 10.2 6.6 39.5 10.7 66.3 3.1 17.9 11.7 8.2 12.5 10.0 16.5 14.5 62.2 35.2 25.5 10.2 0.8 2.9 708.3 9.6 4.4 7.2 2.8 4.5 19.1 8.2 13.0 41.3 14.2 45.7 8.6 7.4 19.5 78.4 24.7 22.1 25.9 0.0 0.3 4.1 28.3 28.4 13.4 13.4 1107.9 9.8 2.6 31.3 14.3 PRKD1 "PKC-mu, PKCM, PKD, PRKCM" ENSG00000184304 "Protein kinase D1" Q15139 14 29576479-30191898 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Angiogenesis, Apoptosis, Differentiation, Immunity, Inflammatory response, Innate immunity, Neurogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant, Ectodermal dysplasia" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 362.1;Excitatory neurons: 147.4;Inhibitory neurons: 171.1;Microglial cells: 89.0;Oligodendrocyte precursor cells: 390.6" "Cancer enhanced" "Detected in all" "prostate cancer: 10.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 21.6;fHDF/TERT166: 19.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB018367, HPA029834" Uncertain Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB018367: AB_2253119, HPA029834: AB_10602821" "unprognostic (5.35e-2)" "unprognostic (3.20e-1)" "unprognostic (2.27e-2)" "unprognostic (6.70e-2)" "unprognostic (2.37e-1)" "unprognostic (1.92e-1)" "unprognostic (1.08e-3)" "unprognostic (8.88e-2)" "unprognostic (2.37e-2)" "unprognostic (5.29e-2)" "unprognostic (7.08e-2)" "unprognostic (1.56e-1)" "prognostic favorable (2.44e-5)" "unprognostic (9.45e-4)" "unprognostic (1.99e-1)" "prognostic unfavorable (2.91e-4)" "unprognostic (3.89e-1)" 8.0 9.6 5.6 2.2 8.0 0.0 7.7 6.5 6.7 6.4 3.7 9.5 1.0 7.9 3.5 2.1 6.5 4.4 6.1 7.5 7.5 17.5 1.6 7.5 0.3 8.6 8.6 11.2 5.4 10.6 5.6 1.9 8.7 14.7 1.3 4.7 2.9 9.3 1.6 2.8 3.6 6.3 8.9 2.3 4.6 11.7 8.1 2.4 5.9 2.6 0.5 13.1 4.6 10.3 0.0 4.4 4.8 3.1 21.6 16.5 0.1 14.1 10.4 16.7 7.3 0.0 0.3 0.0 1.9 19.4 4.0 0.1 7.9 2.1 6.8 0.0 6.2 0.0 0.0 0.5 8.8 0.0 0.1 18.4 0.3 1.4 1.5 6.1 2.6 0.0 1.4 0.4 17.4 1.8 0.0 0.0 2.6 0.0 9.6 0.0 6.3 5.2 9.7 6.6 4.3 13.0 2.6 0.0 4.5 4.6 0.0 0.1 5.6 13.6 6.7 1.0 3.7 0.0 0.0 0.0 3.5 0.0 14.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.6 8.0 6.5 6.7 7.5 7.5 8.6 8.6 8.7 8.9 8.1 10.3 4.6 0.0 7.4 362.1 0.2 0.5 4.8 0.4 0.6 1.4 1.4 1.5 1.2 10.0 0.0 12.9 6.2 0.0 0.0 0.1 29.4 2.4 39.5 2.8 9.2 6.1 3.0 2.7 147.4 4.2 0.1 6.4 0.5 8.4 0.0 18.7 10.8 2.5 0.2 1.7 171.1 0.2 0.0 1.6 0.9 16.9 7.5 0.7 7.2 89.0 0.0 16.7 0.0 390.6 76.6 2.0 0.1 12.8 0.4 12.4 0.2 4.5 0.1 2.9 0.0 13.3 4.5 3.2 7.8 0.0 0.9 0.3 0.6 29.6 0.1 1.3 PROSER2 "C10orf47, MGC35403" ENSG00000148426 "Proline and serine rich 2" Q86WR7 10 11823339-11872277 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 41.0" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 28.4;Glandular and luminal cells: 28.4;Hepatocytes: 31.2;Prostatic glandular cells: 34.6;Urothelial cells: 69.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "A-431: 86.5;CAPAN-2: 99.5;HBEC3-KT: 64.2" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 4 "cerebellum: 14.4" HPA041337 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA 220000 "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA041337: AB_10794663" "unprognostic (2.36e-3)" "unprognostic (1.39e-1)" "unprognostic (3.55e-2)" "unprognostic (1.19e-1)" "unprognostic (4.60e-2)" "unprognostic (7.60e-3)" "unprognostic (4.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.20e-1)" "unprognostic (2.82e-1)" "unprognostic (1.25e-3)" "unprognostic (1.61e-1)" "unprognostic (1.26e-2)" "unprognostic (4.04e-2)" "unprognostic (3.01e-1)" "unprognostic (5.06e-2)" "unprognostic (8.69e-2)" 4.5 1.6 1.9 1.0 2.0 10.4 4.1 1.4 1.6 3.6 4.8 3.1 1.2 3.4 0.5 9.9 3.8 1.7 1.8 1.7 1.8 14.0 41.0 9.8 0.3 1.9 2.3 2.4 7.5 0.5 1.9 7.2 2.0 9.1 1.8 0.1 6.9 2.2 2.0 5.1 1.7 1.0 1.7 7.3 6.6 6.1 3.1 1.9 6.7 0.4 2.8 4.0 6.0 1.3 86.5 12.1 0.7 0.3 2.5 3.1 4.9 3.8 1.8 3.0 1.5 28.1 99.5 0.0 15.1 0.3 1.3 22.1 8.4 64.2 1.5 0.1 20.3 9.8 4.8 18.4 14.2 0.0 5.9 3.6 13.6 17.8 19.9 0.3 9.2 1.6 15.0 0.1 4.3 11.7 0.0 3.2 5.3 11.3 6.9 13.9 11.3 0.0 6.6 4.2 0.1 1.1 6.5 24.9 11.1 4.1 13.1 5.3 6.8 0.1 19.7 33.2 0.4 0.0 0.2 0.1 0.1 3.4 4.7 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.2 1.9 2.0 1.4 1.6 1.7 1.8 1.9 2.3 2.0 1.7 3.1 1.3 3.0 9.6 5.9 1.3 0.0 5.7 28.4 8.2 8.6 0.0 5.5 5.2 1.1 18.6 6.5 5.5 0.0 5.5 0.2 3.2 5.9 11.6 3.0 18.6 2.8 3.7 1.8 2.5 0.7 3.8 18.3 3.6 6.1 28.4 0.0 1.9 1.1 31.2 0.8 0.0 0.7 1.3 2.0 0.3 0.7 3.0 1.8 3.7 3.6 6.5 0.1 0.1 0.0 0.5 0.4 20.0 1.5 4.5 0.0 34.6 0.2 0.8 6.8 0.1 0.0 0.6 1.3 3.7 5.6 4.6 4.7 0.7 0.5 0.7 2.6 69.4 PRRT3 FLJ33674 ENSG00000163704 "Proline rich transmembrane protein 3" Q5FWE3 3 9945542-9952408 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 11.6;fallopian tube: 7.6;parathyroid gland: 15.3;pituitary gland: 11.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 22.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "ASC diff: 17.2;MCF7: 23.1;SK-BR-3: 33.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035127, HPA035128, HPA069859" Enhanced Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA 83000 "Cluster 32: T-cells - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA035127: AB_10602822, HPA035128: AB_2674482, HPA069859: " "unprognostic (1.55e-1)" "unprognostic (8.41e-2)" "unprognostic (3.42e-1)" "unprognostic (2.38e-3)" "unprognostic (1.27e-1)" "unprognostic (3.41e-2)" "unprognostic (1.15e-4)" "unprognostic (2.27e-3)" "unprognostic (1.37e-2)" "unprognostic (2.76e-2)" "unprognostic (2.20e-3)" "unprognostic (3.60e-1)" "unprognostic (1.01e-4)" "unprognostic (2.25e-1)" "unprognostic (1.39e-1)" "unprognostic (4.64e-2)" "unprognostic (2.09e-1)" 0.9 1.8 3.9 1.1 5.0 1.5 1.2 10.1 11.6 1.3 0.3 1.3 0.4 1.2 1.2 1.2 7.6 1.1 1.1 4.4 1.1 1.3 0.4 0.9 1.2 5.1 1.9 1.3 1.8 15.3 11.0 0.3 5.3 2.5 0.3 2.2 2.3 1.7 1.4 2.3 0.9 0.9 0.0 0.9 1.1 2.1 3.6 1.3 2.2 0.2 1.3 1.8 1.1 4.8 0.4 1.0 3.6 4.7 17.2 2.3 1.2 1.8 3.4 2.0 4.5 0.3 3.4 2.0 0.4 4.2 2.1 0.3 1.3 4.5 0.9 9.8 2.0 0.7 1.9 0.2 1.7 0.4 1.7 4.4 0.3 1.7 0.7 9.7 0.8 6.0 1.0 4.7 2.5 23.1 4.4 0.4 8.5 0.1 2.1 2.8 0.4 1.9 1.0 0.4 6.6 4.4 1.8 33.6 0.7 1.4 9.1 0.4 0.7 0.4 4.6 0.9 1.3 6.1 6.6 0.6 10.9 0.3 1.3 0.5 0.2 0.2 1.2 0.1 1.4 0.5 1.3 1.2 0.0 0.6 1.4 1.3 0.3 0.7 0.1 0.6 0.2 0.4 3.9 5.0 10.1 11.6 4.4 1.1 5.1 1.9 5.3 0.0 3.6 4.8 3.3 0.0 2.0 3.9 2.9 2.7 3.8 3.7 3.4 22.8 7.4 6.2 3.0 7.2 3.4 11.0 14.6 0.7 4.4 4.5 3.9 2.9 4.3 5.0 5.4 3.3 11.3 2.1 14.7 5.0 0.5 5.2 5.6 4.9 1.3 7.9 2.2 2.9 3.8 15.2 10.8 5.4 2.0 2.5 2.6 3.5 5.6 2.2 1.8 2.8 11.3 8.6 11.3 5.5 3.7 3.1 1.0 2.6 2.2 4.2 6.4 8.0 12.4 21.6 0.0 7.2 5.3 10.4 6.4 3.4 2.3 0.4 5.6 7.8 4.7 3.0 PSMC5 "p45, p45/SUG, S8, SUG-1, SUG1, TBP10, TRIP1" ENSG00000087191 "Proteasome 26S subunit, ATPase 5" P62195 17 63827152-63832026 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 596.6;Late spermatids: 1350.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA017871, HPA064293" Enhanced Supported "Plasma membrane,Cytosol" NA NA 120000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 39: Non-specific - Mitochondria" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA017871: AB_1857638, HPA064293: AB_2685234" "unprognostic (9.65e-2)" "unprognostic (1.63e-2)" "unprognostic (4.44e-1)" "unprognostic (2.91e-2)" "unprognostic (1.61e-1)" "unprognostic (1.35e-1)" "unprognostic (8.29e-3)" "unprognostic (1.24e-2)" "unprognostic (3.38e-1)" "unprognostic (2.85e-1)" "unprognostic (2.17e-2)" "unprognostic (1.25e-1)" "prognostic unfavorable (3.13e-6)" "unprognostic (9.54e-2)" "unprognostic (8.57e-2)" "unprognostic (1.15e-1)" "unprognostic (2.32e-1)" 90.4 99.0 134.8 80.9 137.5 82.4 80.6 141.3 159.0 79.6 130.2 106.1 68.0 80.1 112.3 104.9 83.2 59.4 107.5 136.2 139.3 120.9 112.7 68.1 93.0 140.5 140.2 63.3 71.0 161.1 82.5 75.5 141.2 81.4 84.4 85.3 73.4 86.7 236.2 121.5 70.6 90.3 137.7 82.4 84.5 73.3 139.6 93.3 86.4 168.7 108.0 93.4 79.6 138.9 240.1 369.1 233.9 172.9 171.4 174.7 202.8 225.3 197.0 327.1 243.8 390.3 154.7 158.7 154.7 241.6 246.0 182.8 239.1 228.5 383.5 136.8 289.7 330.3 288.9 362.4 180.1 336.0 230.4 177.5 171.4 291.9 266.6 139.1 263.7 180.9 258.4 210.2 284.9 450.7 279.4 237.4 215.6 266.3 330.0 248.9 445.5 244.3 249.0 270.9 203.2 274.1 158.6 313.9 152.3 254.4 306.8 197.8 238.8 360.3 329.9 161.5 482.6 220.5 335.2 250.4 225.8 255.7 241.5 105.1 120.4 149.4 164.1 176.3 222.8 142.7 191.6 179.3 140.0 122.0 161.3 183.1 37.7 167.4 206.3 108.6 272.1 216.1 134.8 137.5 141.3 159.0 136.2 139.3 140.5 140.2 141.2 137.7 139.6 138.9 97.9 51.3 78.6 8.5 82.7 94.6 145.0 206.3 71.7 84.9 71.1 79.1 156.0 110.1 139.6 68.0 18.8 250.4 85.1 98.8 246.5 195.2 596.6 75.4 69.4 104.7 90.9 107.7 7.9 214.5 187.2 101.4 69.3 68.1 90.2 53.3 86.4 130.9 162.9 72.3 7.9 92.7 197.4 89.8 85.0 1350.2 133.0 93.4 99.6 5.6 148.0 221.4 109.2 7.5 10.5 167.5 96.3 153.4 88.0 125.6 163.7 330.3 95.1 108.4 111.7 113.0 228.7 151.6 150.2 95.0 102.9 369.0 102.9 124.7 97.9 137.9 PSMD9 "p27, Rpn4" ENSG00000110801 "Proteasome 26S subunit, non-ATPase 9" O00233 12 121888732-121918297 "Plasma proteins, Predicted intracellular proteins" Chaperone "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA040512, HPA044220" Enhanced Supported "Plasma membrane,Cytosol" NA NA 500000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 59: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA040512: AB_2677014, HPA044220: AB_2678860" "unprognostic (2.24e-1)" "unprognostic (2.48e-3)" "unprognostic (2.12e-1)" "unprognostic (3.36e-1)" "unprognostic (1.20e-2)" "unprognostic (1.51e-1)" "prognostic unfavorable (1.32e-5)" "unprognostic (1.86e-1)" "unprognostic (6.80e-2)" "unprognostic (1.01e-1)" "unprognostic (1.46e-1)" "unprognostic (1.30e-1)" "unprognostic (9.64e-3)" "unprognostic (3.17e-2)" "unprognostic (5.73e-2)" "unprognostic (6.19e-2)" "unprognostic (8.63e-2)" 16.5 4.6 7.5 2.3 8.1 19.2 4.8 8.0 10.0 5.8 11.8 13.8 11.5 7.1 2.2 6.2 6.4 3.8 5.5 7.9 8.1 10.8 4.6 6.0 5.7 9.0 8.9 5.9 10.6 4.8 3.5 3.9 8.3 4.6 2.2 3.6 8.8 6.7 18.5 5.9 6.2 3.3 8.3 8.9 14.9 5.1 8.7 6.6 5.1 6.0 3.2 4.1 5.5 9.4 54.8 81.8 6.7 12.2 11.2 11.6 13.9 54.5 17.8 27.3 15.5 60.0 6.3 40.5 45.0 28.6 9.2 22.1 20.0 29.1 16.3 78.5 41.6 33.3 40.9 30.5 27.5 23.3 22.7 20.4 14.0 30.4 11.7 9.9 16.6 24.7 30.1 5.3 17.6 63.2 47.1 17.8 14.0 7.1 63.4 35.6 18.3 24.9 13.4 53.9 14.1 19.3 54.4 7.7 29.3 5.8 23.3 11.3 43.3 25.4 29.0 50.1 38.4 30.4 73.0 62.1 45.5 30.1 23.8 41.8 43.6 53.0 33.9 46.2 27.3 47.6 32.6 31.0 38.5 38.5 25.0 21.2 41.3 29.3 41.7 63.7 48.1 51.6 7.5 8.1 8.0 10.0 7.9 8.1 9.0 8.9 8.3 8.3 8.7 9.4 22.8 48.1 33.7 10.1 32.6 60.5 11.4 64.1 67.2 7.3 40.9 34.8 8.0 34.3 40.0 35.0 18.8 30.3 45.8 66.6 52.8 116.9 34.9 32.6 28.7 29.7 46.6 121.4 12.9 121.4 30.7 30.5 42.8 27.4 44.4 11.0 33.9 26.8 39.8 15.2 10.7 66.5 54.9 37.9 55.3 11.4 37.9 43.6 55.2 7.5 93.9 17.2 35.0 7.1 18.7 138.2 64.2 38.7 73.2 9.5 146.8 100.7 36.6 14.8 39.5 19.5 46.8 33.9 37.5 69.4 71.6 37.8 44.9 12.9 67.7 12.8 PSTPIP1 "CD2BP1, CD2BP1L, CD2BP1S, H-PIP, PAPAS, PSTPIP" ENSG00000140368 "Proline-serine-threonine phosphatase interacting protein 1" O43586 15 76993359-77037475 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cell adhesion, Endocytosis, Immunity, Inflammatory response, Innate immunity" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 56.6;lymphoid tissue: 33.9" "Cell type enhanced" "Detected in many" "dendritic cells: 60.0;Enteroendocrine cells: 60.0;Hofbauer cells: 42.5;Kupffer cells: 41.8;Macrophages: 41.8;monocytes: 51.1;NK-cells: 91.6;T-cells: 68.4;Theca cells: 78.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 55.1;HL-60: 14.4;NB-4: 20.9;THP-1: 14.7;U-937: 59.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA010116, HPA010600, HPA072744" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 32: U-937 - Innate immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA010116: , HPA010600: AB_1855870, HPA072744: " "unprognostic (4.42e-3)" "unprognostic (1.31e-3)" "unprognostic (3.56e-2)" "prognostic favorable (4.74e-5)" "unprognostic (3.79e-2)" "unprognostic (1.12e-3)" "unprognostic (2.16e-2)" "unprognostic (1.23e-2)" "unprognostic (1.16e-1)" "unprognostic (9.85e-2)" "unprognostic (2.96e-2)" "unprognostic (3.18e-1)" "prognostic unfavorable (7.36e-9)" "unprognostic (1.39e-1)" "unprognostic (1.84e-1)" "unprognostic (1.91e-1)" "unprognostic (5.42e-2)" 6.0 2.6 2.8 11.7 2.7 56.6 2.3 2.7 3.1 2.0 3.4 3.3 2.5 1.6 0.1 2.0 3.1 2.9 2.4 2.7 2.8 3.4 3.4 10.4 13.5 3.1 3.1 1.0 1.3 0.2 1.6 1.8 3.0 2.9 0.8 0.1 2.4 1.0 1.5 1.8 9.4 1.4 3.1 33.9 2.9 0.7 3.6 4.2 2.9 1.0 5.5 4.3 2.7 3.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.2 0.0 0.1 0.0 55.1 0.0 0.0 0.0 3.3 0.0 14.4 0.1 0.2 0.1 0.0 0.1 0.0 0.0 3.0 0.0 0.0 0.0 0.0 2.4 20.9 0.1 0.0 0.0 0.8 0.0 0.1 0.0 0.1 4.0 0.6 0.0 0.1 0.0 0.0 0.0 14.7 0.0 0.0 0.1 0.1 0.0 0.0 1.3 2.4 0.1 59.8 0.0 4.8 71.5 71.4 39.9 33.5 30.8 13.3 27.2 32.7 59.0 18.5 14.3 22.3 85.3 41.6 38.3 5.2 27.0 42.2 2.8 2.7 2.7 3.1 2.7 2.8 3.1 3.1 3.0 3.1 3.6 3.1 1.1 0.0 5.1 1.0 19.2 9.3 1.2 0.4 0.0 1.1 0.9 1.1 1.9 0.0 2.5 0.0 0.0 0.3 60.0 3.1 0.0 0.0 9.6 0.3 0.3 0.8 60.0 4.8 0.4 0.2 0.7 1.9 0.0 0.3 2.5 0.1 2.2 0.9 42.5 0.0 0.1 6.1 2.0 41.8 36.5 18.6 0.9 41.8 7.2 0.0 51.1 0.2 91.6 5.5 1.0 0.1 2.5 2.6 8.5 0.3 0.3 0.4 0.0 0.4 0.0 0.8 3.1 0.2 1.2 0.2 4.8 0.5 68.4 78.1 0.3 1.2 PTCH2 ENSG00000117425 "Patched 2" Q9Y6C5 1 44819844-44843253 "Cancer-related genes, Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" Receptor "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "ovary: 24.6;parathyroid gland: 59.1;salivary gland: 75.2;testis: 25.6" "Cell type enhanced" "Detected in many" "Leydig cells: 107.8;Peritubular cells: 68.1;Plasma cells: 67.1;Theca cells: 138.7" "Cancer enhanced" "Detected in many" "testis cancer: 9.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-266/84: 11.6" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046839 Supported "Nucleoli,Plasma membrane" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 16: U-266 - Nucleosome" "Cluster 52: Non-specific - Transcription" "Plasma membrane" Nucleoli "HPA046839: " "unprognostic (6.54e-5)" "unprognostic (1.05e-1)" "unprognostic (7.29e-3)" "unprognostic (3.65e-3)" "unprognostic (3.89e-1)" "unprognostic (7.42e-3)" "unprognostic (3.01e-1)" "unprognostic (2.94e-2)" "unprognostic (1.51e-1)" "unprognostic (8.67e-2)" "prognostic favorable (5.74e-5)" "unprognostic (2.92e-1)" "unprognostic (5.74e-6)" "unprognostic (1.55e-2)" "unprognostic (4.86e-2)" "unprognostic (6.31e-2)" "unprognostic (6.81e-2)" 4.2 3.1 6.1 0.8 3.5 9.4 3.4 6.8 6.8 5.1 3.6 3.6 1.0 6.4 1.6 0.9 4.3 2.5 1.3 3.1 4.4 1.3 1.3 1.0 2.3 2.9 4.8 24.6 1.0 59.1 9.9 0.3 2.0 3.0 0.9 3.6 75.2 1.3 2.0 3.6 1.8 1.2 1.6 2.4 2.0 25.6 6.5 0.8 4.6 0.8 0.7 3.1 3.4 4.8 0.2 0.3 1.0 2.5 0.8 0.9 1.0 0.8 1.6 0.5 0.4 0.2 0.4 1.1 0.4 0.4 0.5 0.0 1.1 0.0 0.2 2.1 1.9 0.6 1.0 0.8 0.3 0.7 1.1 0.3 0.4 1.0 0.1 1.7 0.1 1.0 0.7 1.1 0.0 0.5 1.4 2.1 0.3 0.1 0.4 1.0 0.2 0.5 0.2 0.0 1.5 0.6 0.3 0.4 0.8 0.5 0.2 1.2 0.1 0.2 0.5 1.3 0.5 1.9 11.6 3.2 0.6 3.0 0.4 2.5 1.9 0.1 0.5 0.9 1.0 1.0 0.6 0.6 1.2 1.4 0.7 0.6 0.6 0.9 0.9 3.6 0.3 0.2 6.1 3.5 6.8 6.8 3.1 4.4 2.9 4.8 2.0 1.6 6.5 4.8 2.8 0.0 1.1 14.0 13.4 0.5 0.7 1.0 0.6 0.8 4.8 8.0 1.0 7.2 1.0 1.8 2.1 2.4 6.8 7.8 0.0 5.5 2.3 9.3 13.5 2.7 11.5 1.3 23.7 1.8 1.6 14.3 28.1 8.5 0.0 4.4 0.7 7.9 6.7 8.4 27.3 4.9 2.0 24.5 2.2 8.0 107.8 17.3 0.0 5.6 3.9 2.4 2.1 9.5 2.6 2.1 2.5 68.1 67.1 0.8 13.6 0.2 1.7 1.2 13.1 5.4 5.6 5.0 3.6 0.6 1.6 2.3 7.5 138.7 5.5 0.2 PTCHD4 "C6orf138, dJ402H5.2, FLJ41841, PTCH53" ENSG00000244694 "Patched domain containing 4" Q6ZW05 6 47856673-48111197 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in some" "Cell type enriched" "Detected in some" 5 "Inhibitory neurons: 479.8" "Group enriched" "Detected in some" 6 "melanoma: 1.1;renal cancer: 1.6;thyroid cancer: 4.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 9.4;BEWO: 12.4;Hep G2: 21.8;LHCN-M2: 9.6;SuSa: 20.1;TIME: 9.9;WM-115: 11.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" HPA041276 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 68: Epididymis - Unknown function" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane, Cytosol" "HPA041276: AB_10796570" "unprognostic (1.35e-4)" "unprognostic (1.66e-2)" "unprognostic (3.25e-1)" "unprognostic (3.11e-3)" "unprognostic (1.07e-2)" "unprognostic (1.57e-3)" "unprognostic (7.94e-2)" "unprognostic (3.59e-3)" "unprognostic (2.80e-1)" "unprognostic (1.50e-1)" "unprognostic (2.55e-1)" "unprognostic (1.92e-1)" "prognostic favorable (1.49e-6)" "unprognostic (5.03e-4)" "unprognostic (9.84e-2)" "unprognostic (1.57e-2)" "unprognostic (5.56e-3)" 0.5 0.1 0.6 0.0 0.6 0.0 0.3 0.0 1.5 0.6 0.1 0.3 0.1 0.3 0.6 0.3 0.5 0.2 0.5 0.8 0.5 0.4 0.3 0.5 0.0 0.2 1.0 0.2 0.2 0.0 0.9 0.3 0.0 0.5 0.1 0.8 0.5 1.0 0.1 0.0 0.1 0.3 0.5 0.0 0.1 0.2 0.3 0.0 0.8 0.1 0.0 0.3 0.3 0.4 0.0 0.0 9.4 0.0 1.3 3.9 12.4 1.2 2.8 0.0 0.4 0.0 0.5 0.0 0.0 0.9 0.0 0.0 0.0 1.0 0.1 0.0 0.0 0.0 0.2 21.8 0.5 0.0 0.0 6.2 5.4 0.0 0.1 4.4 1.8 2.5 0.0 0.0 9.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.0 1.8 0.5 0.1 0.0 0.0 20.1 0.0 0.0 9.9 2.3 1.9 0.0 0.2 0.0 0.0 0.0 3.3 0.0 11.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.6 0.0 1.5 0.8 0.5 0.2 1.0 0.0 0.5 0.3 0.4 0.5 0.0 1.1 6.5 0.0 0.1 0.0 1.0 0.0 1.0 0.4 0.3 0.2 0.0 1.3 1.8 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.6 0.0 0.0 90.6 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 479.8 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 89.9 0.0 0.6 0.0 2.5 2.8 0.1 0.0 0.4 0.0 0.2 0.0 0.0 1.1 0.9 0.0 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 PTK2B "CADTK, CAKB, FAK2, PTK, PYK2, RAFTK" ENSG00000120899 "Protein tyrosine kinase 2 beta" Q14289 8 27311482-27459391 "Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Adaptive immunity, Angiogenesis, Immunity" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 106.3;brain: 102.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 109.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 127.4;REH: 141.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003850, HPA026091, HPA026276" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 8: Neutrophils - Inflammatory response" "Cluster 10: Brain - Neuronal signaling" "Cluster 14: REH - Unknown function" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "CAB003850: AB_562205, HPA026091: AB_10599739, HPA026276: AB_10601234" "unprognostic (2.36e-2)" "prognostic favorable (3.32e-4)" "unprognostic (1.06e-1)" "unprognostic (7.36e-3)" "unprognostic (3.72e-2)" "unprognostic (3.11e-2)" "unprognostic (2.70e-2)" "unprognostic (2.13e-2)" "unprognostic (3.23e-1)" "unprognostic (1.45e-1)" "unprognostic (5.74e-2)" "unprognostic (3.32e-1)" "unprognostic (2.40e-3)" "unprognostic (1.44e-1)" "unprognostic (1.38e-1)" "prognostic favorable (5.11e-4)" "unprognostic (3.33e-3)" 19.7 10.8 46.9 52.6 54.4 106.3 11.5 22.8 102.9 11.5 38.3 29.8 34.1 9.9 8.9 19.2 15.6 12.7 10.6 96.3 8.5 15.9 15.2 28.6 78.3 0.0 26.0 4.7 12.6 7.1 13.7 8.0 0.0 25.5 23.5 4.4 26.6 12.3 5.0 45.2 48.8 10.7 0.2 78.3 22.2 9.5 27.0 86.0 12.5 5.4 73.6 21.0 15.1 37.0 38.2 10.4 2.8 3.0 76.6 5.5 21.5 2.9 1.9 1.9 2.7 9.9 21.5 127.4 4.0 5.8 3.1 34.3 1.1 31.3 1.1 8.7 0.8 26.4 10.6 2.0 15.7 28.5 45.5 41.6 46.0 2.6 17.3 13.0 1.0 36.0 31.7 85.6 2.1 4.0 49.1 57.0 2.2 33.0 2.6 141.2 0.7 88.3 8.5 29.5 19.2 3.5 13.4 9.3 5.0 6.5 11.5 72.1 17.5 1.3 2.8 2.5 1.0 68.0 32.0 68.9 5.2 60.6 2.4 47.3 48.4 36.9 33.9 43.0 22.2 46.0 17.0 24.3 36.1 46.6 20.8 25.9 45.8 29.0 53.5 11.7 18.2 50.1 46.9 54.4 22.8 102.9 96.3 8.5 0.0 26.0 0.0 0.2 27.0 37.0 6.9 3.2 29.8 16.6 64.3 37.7 38.7 19.7 6.8 5.4 5.9 7.7 3.7 8.6 13.0 14.7 0.0 2.9 33.4 65.5 0.0 8.0 1.2 7.1 1.8 9.6 7.8 20.2 109.2 8.3 26.5 3.5 22.4 5.3 28.5 1.1 5.0 24.1 23.1 8.4 9.2 21.9 10.2 68.4 32.1 1.0 1.5 55.3 8.8 22.5 62.5 2.8 70.0 7.5 15.1 13.3 42.0 0.7 68.1 18.6 44.6 16.1 13.9 3.9 0.0 3.3 3.3 4.2 6.4 4.8 30.1 1.9 46.6 1.0 18.1 17.9 PTPN12 "PTP-PEST, PTPG1" ENSG00000127947 "Protein tyrosine phosphatase non-receptor type 12" Q05209 7 77537295-77640069 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Hydrolase, Protein phosphatase" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA007097 Approved Approved "Plasma membrane,Cytosol" NA NA 770000 "Cluster 40: NK-cells - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane, Cytosol" "HPA007097: AB_1079689" "unprognostic (2.28e-1)" "prognostic unfavorable (1.15e-4)" "unprognostic (1.35e-1)" "unprognostic (3.35e-2)" "unprognostic (1.40e-3)" "unprognostic (4.48e-3)" "prognostic unfavorable (8.78e-4)" "unprognostic (1.29e-1)" "unprognostic (5.83e-2)" "unprognostic (2.64e-1)" "prognostic unfavorable (2.01e-4)" "unprognostic (1.09e-1)" "prognostic unfavorable (7.27e-6)" "unprognostic (4.99e-2)" "unprognostic (2.97e-1)" "unprognostic (1.81e-1)" "unprognostic (3.21e-1)" 60.5 30.1 24.2 43.9 26.6 69.9 50.3 29.2 31.6 40.9 25.9 48.9 18.9 38.6 18.6 38.5 39.6 40.2 39.0 25.1 27.3 36.1 30.9 65.0 27.5 28.5 27.8 34.6 20.1 21.0 21.9 74.7 30.5 26.4 27.7 30.9 23.8 33.2 24.6 36.9 29.7 40.2 26.7 52.7 27.1 30.1 32.7 33.9 31.0 44.5 27.5 46.7 39.6 30.2 72.4 43.5 100.6 51.8 69.1 71.7 54.2 73.3 93.0 56.6 80.0 21.6 109.9 8.6 23.2 86.3 123.6 50.2 34.2 73.4 113.3 21.2 19.2 44.9 44.2 88.4 67.7 25.8 28.8 59.0 80.3 123.2 157.6 101.0 121.6 2.1 54.9 12.2 182.6 49.4 3.6 71.9 81.7 97.6 49.2 15.1 80.6 4.5 97.6 38.5 12.5 66.6 90.4 81.5 73.4 172.2 39.5 93.9 89.3 121.4 73.1 45.0 141.3 12.6 7.4 22.2 71.6 65.9 215.7 3.6 4.1 6.8 3.1 2.8 1.3 2.3 1.1 2.6 3.8 1.0 0.6 3.3 9.5 13.3 5.3 0.3 1.6 2.7 24.2 26.6 29.2 31.6 25.1 27.3 28.5 27.8 30.5 26.7 32.7 30.2 139.3 70.5 56.2 30.0 18.2 68.8 60.0 55.9 23.9 16.7 40.9 26.3 41.3 28.6 46.4 20.2 8.4 40.0 89.0 31.2 3.9 42.1 3.5 43.9 62.4 114.4 12.1 16.6 65.8 39.6 58.7 54.6 21.4 87.2 14.5 21.7 119.2 24.6 50.1 35.3 58.0 21.7 28.5 82.0 121.3 6.7 46.6 96.1 35.6 93.7 54.9 66.9 163.7 70.4 67.3 75.0 21.4 47.0 17.6 62.0 10.9 19.2 23.2 15.2 65.7 127.9 66.8 51.2 71.4 29.8 101.4 72.1 27.3 24.4 23.3 104.8 PTPRS ENSG00000105426 "Protein tyrosine phosphatase receptor type S" Q13332 19 5158495-5340803 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Heparin-binding, Hydrolase, Protein phosphatase, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 76.8;Inhibitory neurons: 104.2;Melanocytes: 80.0;Oligodendrocytes: 90.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in single" 89 "plasmacytoid DC: 12.5" "Lineage enriched" "Detected in single" 89 "dendritic cells: 12.5" "Cell line enhanced" "Detected in many" "AN3-CA: 121.8;HaCaT: 124.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA054747 Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 150000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA054747: AB_2682591" "unprognostic (8.14e-2)" "unprognostic (4.59e-3)" "unprognostic (2.57e-2)" "unprognostic (9.20e-2)" "unprognostic (2.15e-1)" "unprognostic (6.96e-3)" "unprognostic (6.85e-2)" "unprognostic (2.36e-1)" "unprognostic (3.12e-3)" "unprognostic (1.86e-1)" "prognostic favorable (1.07e-4)" "unprognostic (1.25e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (2.80e-1)" "unprognostic (1.45e-1)" "unprognostic (4.05e-1)" "unprognostic (3.46e-2)" 54.7 21.2 34.4 5.0 25.5 1.5 36.2 3.2 30.9 40.2 0.0 25.2 2.6 30.5 2.2 16.5 41.1 13.7 37.0 34.3 10.0 11.2 6.0 26.9 5.5 16.4 16.4 35.8 32.4 9.7 29.1 2.3 17.6 30.5 1.6 5.7 18.6 14.6 14.4 20.6 13.6 8.6 1.6 9.0 23.2 9.9 27.3 4.2 29.4 7.4 4.4 32.0 31.8 34.9 11.3 64.0 56.2 121.8 25.3 20.5 7.4 19.4 22.5 22.8 18.5 0.7 6.2 0.2 44.5 32.2 18.0 124.6 15.1 0.2 10.0 1.5 24.3 0.0 27.2 40.5 11.7 0.0 14.1 21.8 5.4 4.8 0.9 29.4 0.6 7.9 18.5 0.2 9.1 48.0 5.2 12.3 31.7 0.4 27.0 0.0 12.4 0.0 4.7 22.5 43.1 58.9 18.3 3.4 34.6 10.7 22.0 4.8 2.8 20.2 34.3 46.9 23.6 6.2 0.1 36.9 10.5 0.0 44.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.5 0.0 0.0 34.4 25.5 3.2 30.9 34.3 10.0 16.4 16.4 17.6 1.6 27.3 34.9 1.1 6.4 1.1 53.8 3.2 60.9 42.4 16.1 22.2 49.6 3.3 5.5 14.1 27.1 4.9 12.9 2.1 0.7 56.4 0.1 9.8 1.4 3.4 5.4 11.4 9.7 3.0 0.0 76.8 0.9 32.2 51.2 5.1 5.3 0.0 4.0 25.4 20.2 1.7 11.8 104.2 0.0 10.2 0.3 20.0 5.4 46.6 3.4 80.0 15.9 0.8 46.6 0.0 71.9 90.2 0.5 0.0 36.1 6.3 35.0 0.0 2.9 1.7 10.1 13.1 46.4 22.6 7.4 14.8 16.8 36.7 1.0 2.0 2.7 0.4 30.0 PYGL GSD6 ENSG00000100504 "Glycogen phosphorylase L" P06737 14 50857891-50944483 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Carbohydrate metabolism, Glycogen metabolism" "Allosteric enzyme, Glycosyltransferase, Transferase" "Disease variant, Glycogen storage disease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 145.6" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 151.2;Hofbauer cells: 177.6;Muller glia cells: 265.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "eosinophil: 141.1;neutrophil: 153.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HaCaT: 279.1;HMC-1: 304.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000962, HPA004119" Enhanced Supported "Plasma membrane,Cytosol" NA NA 16000000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane, Cytosol" "HPA000962: AB_1079722, HPA004119: AB_1079723" "unprognostic (2.70e-2)" "unprognostic (8.64e-3)" "unprognostic (1.46e-2)" "unprognostic (8.55e-2)" "unprognostic (9.41e-2)" "prognostic unfavorable (5.97e-4)" "unprognostic (1.66e-1)" "unprognostic (1.34e-2)" "unprognostic (3.34e-1)" "unprognostic (1.94e-2)" "prognostic unfavorable (2.63e-4)" "unprognostic (4.45e-3)" "unprognostic (3.15e-3)" "unprognostic (1.95e-2)" "unprognostic (1.76e-1)" "unprognostic (9.72e-2)" "unprognostic (1.12e-3)" 110.1 21.0 5.9 24.1 6.6 108.9 36.4 5.0 8.4 33.6 10.4 19.0 3.7 20.7 6.4 55.8 19.1 13.0 14.9 5.2 6.2 10.2 145.6 26.1 6.3 10.7 17.6 18.2 5.7 21.1 7.5 49.3 8.7 13.0 24.0 78.2 26.8 29.7 5.1 37.0 8.4 26.7 8.6 49.4 9.6 5.2 9.0 4.8 10.2 5.8 6.8 41.7 38.1 10.3 145.7 40.8 10.1 64.3 47.0 56.2 114.5 28.6 24.1 77.4 117.3 107.4 18.3 0.1 54.4 171.7 91.2 279.1 107.0 144.8 132.0 0.5 46.8 28.0 60.5 82.4 83.8 106.9 304.4 119.4 56.8 104.1 43.6 75.4 69.3 0.8 11.6 0.5 55.4 144.7 0.4 141.7 39.3 12.8 152.0 2.7 36.2 6.1 104.7 95.1 4.5 4.4 131.0 43.3 1.7 38.6 20.6 200.4 3.2 29.7 49.6 56.0 92.9 1.2 0.3 0.5 27.3 107.7 15.9 50.2 55.9 141.1 0.0 24.2 0.0 0.0 0.0 0.0 27.3 0.0 0.0 0.0 153.7 0.6 15.7 1.2 0.2 24.8 5.9 6.6 5.0 8.4 5.2 6.2 10.7 17.6 8.7 8.6 9.0 10.3 6.7 22.4 6.3 1.3 1.8 30.7 10.5 40.5 6.8 4.6 7.0 3.8 3.4 5.7 35.4 7.3 0.0 28.9 0.2 11.2 3.9 10.9 1.0 35.4 18.9 7.8 1.2 9.0 1.8 2.1 151.2 18.8 6.6 62.6 6.3 9.3 8.2 65.4 177.6 1.7 2.2 7.1 14.2 56.7 7.9 1.5 14.3 54.6 19.6 15.9 52.4 265.1 2.1 14.1 0.6 7.4 5.2 21.8 1.8 9.7 0.0 6.4 24.5 11.9 6.6 15.4 8.8 0.7 1.4 22.4 22.3 21.1 2.3 4.0 14.0 9.2 PYGO2 ENSG00000163348 "Pygopus family PHD finger 2" Q9BRQ0 1 154957026-154963853 "Predicted intracellular proteins" "Wnt signaling pathway" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA023689, HPA074813" Supported Supported "Nucleoplasm,Plasma membrane" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" Nucleoplasm "Plasma membrane" "HPA023689: AB_1855974, HPA074813: " "unprognostic (1.49e-2)" "unprognostic (1.33e-1)" "unprognostic (6.96e-3)" "unprognostic (2.58e-2)" "unprognostic (5.85e-2)" "unprognostic (4.32e-3)" "prognostic unfavorable (3.88e-6)" "unprognostic (2.45e-1)" "unprognostic (2.07e-1)" "unprognostic (2.00e-2)" "unprognostic (1.51e-1)" "unprognostic (3.74e-1)" "unprognostic (7.40e-3)" "unprognostic (1.63e-2)" "unprognostic (2.81e-2)" "unprognostic (2.17e-1)" "prognostic favorable (1.76e-4)" 14.6 30.6 30.0 16.7 30.3 6.5 15.3 29.3 29.8 21.4 21.1 23.5 19.0 19.1 23.5 24.2 20.3 12.7 15.5 29.9 34.0 24.7 20.1 15.7 26.5 30.5 30.8 27.2 18.1 27.5 32.4 16.3 29.1 23.5 15.3 12.7 23.2 23.3 18.9 22.4 24.4 15.7 29.8 28.2 21.6 16.1 35.3 22.5 26.2 15.9 27.8 21.2 20.0 32.3 28.1 19.4 40.4 36.0 39.8 19.5 37.0 17.1 23.0 26.5 22.7 26.1 34.2 34.9 26.4 19.9 28.7 37.2 35.6 23.7 17.4 34.7 25.1 27.9 32.7 23.6 18.5 25.8 23.9 16.2 33.8 23.9 20.0 30.0 16.5 52.5 37.1 57.6 25.2 42.8 36.0 30.0 43.3 55.7 34.2 40.2 25.7 55.6 27.1 26.1 48.4 71.8 27.0 48.5 34.9 39.1 59.7 45.9 14.1 23.5 35.1 25.6 25.1 56.8 54.3 37.1 19.6 32.4 31.8 2.3 3.9 10.9 8.0 6.5 10.0 6.9 10.3 10.7 4.1 7.5 11.0 8.7 3.8 6.3 8.4 3.9 5.8 6.2 30.0 30.3 29.3 29.8 29.9 34.0 30.5 30.8 29.1 29.8 35.3 32.3 7.0 9.6 4.9 5.5 12.6 5.5 3.8 5.8 7.4 11.8 14.3 10.0 5.3 5.7 7.4 12.9 2.1 15.5 14.1 10.3 19.6 6.2 3.4 5.7 7.5 6.8 5.4 12.4 6.3 5.9 12.6 5.8 9.7 7.4 0.0 9.3 7.1 9.4 6.5 21.9 4.3 10.6 6.1 6.6 3.5 2.2 9.0 5.6 5.4 6.5 6.4 10.6 8.2 5.5 4.7 9.7 9.1 9.1 11.5 4.9 12.0 9.8 4.0 6.0 6.6 5.4 6.9 5.9 12.2 9.8 5.3 11.6 11.7 9.3 8.4 3.7 RAB13 ENSG00000143545 "RAB13, member RAS oncogene family" P51153 1 153981617-153986358 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 10 "classical monocyte: 7.0;myeloid DC: 10.5;plasmacytoid DC: 12.9" "Group enriched" "Detected in many" 11 "dendritic cells: 12.9;monocytes: 7.0" "Cell line enhanced" "Detected in many" "ASC TERT1: 846.1" HPA003996 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "HPA003996: AB_1079728" "unprognostic (4.39e-3)" "unprognostic (1.20e-1)" "unprognostic (2.51e-2)" "unprognostic (4.11e-2)" "unprognostic (4.28e-3)" "unprognostic (3.20e-2)" "unprognostic (1.18e-3)" "unprognostic (2.80e-1)" "unprognostic (3.53e-2)" "unprognostic (2.11e-2)" "unprognostic (2.10e-1)" "unprognostic (5.93e-2)" "unprognostic (1.06e-3)" "unprognostic (2.45e-1)" "unprognostic (1.03e-1)" "unprognostic (9.51e-3)" "unprognostic (1.28e-2)" 151.4 132.8 78.8 91.0 80.1 104.3 124.1 79.4 112.4 114.1 89.2 123.6 54.1 92.2 111.3 102.0 96.0 83.3 90.1 77.3 88.6 164.6 111.1 116.8 42.5 92.5 85.3 111.1 115.1 97.9 35.4 64.3 89.7 123.5 73.6 10.5 96.3 73.5 45.9 92.1 79.0 67.5 84.7 97.5 123.3 61.7 84.0 19.2 112.8 49.5 47.7 123.2 107.7 83.7 133.4 162.5 143.7 152.8 478.2 846.1 43.2 157.9 381.1 142.6 144.6 165.4 111.9 0.1 230.7 194.4 72.7 88.4 86.9 146.7 198.0 78.6 62.3 110.1 100.5 94.3 199.5 0.4 70.9 620.1 125.3 246.6 109.1 401.0 253.4 0.0 20.6 0.5 246.6 280.0 0.5 55.4 231.8 183.9 151.2 28.9 186.1 0.1 327.0 140.5 7.2 112.6 208.7 179.8 337.0 215.4 294.2 87.0 469.6 256.0 149.5 161.1 174.7 0.4 0.1 0.9 399.6 17.4 399.7 0.0 7.0 0.1 0.0 1.0 0.1 0.7 0.1 0.0 10.5 0.6 0.1 0.4 0.8 0.0 0.1 12.9 0.0 1.9 78.8 80.1 79.4 112.4 77.3 88.6 92.5 85.3 89.7 84.7 84.0 83.7 230.1 41.7 83.4 1.0 9.0 92.0 181.3 196.3 110.4 1.2 126.9 149.2 75.2 120.1 105.3 108.5 2.1 116.3 2.8 81.5 135.0 234.4 119.9 91.9 163.2 239.8 89.1 116.4 0.0 149.2 181.2 100.8 76.5 111.4 40.6 111.9 192.4 136.2 249.1 0.0 0.0 184.2 83.4 111.1 104.5 232.1 106.2 116.0 99.6 7.5 247.4 71.5 2.1 0.0 0.1 158.1 110.6 124.1 10.6 197.0 135.7 206.5 72.2 3.8 151.2 46.9 151.4 103.6 18.4 124.8 98.2 92.9 8.9 141.6 146.1 195.9 RAB23 ENSG00000112210 "RAB23, member RAS oncogene family" Q9ULC3 6 57186992-57222307 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Protein transport, Transport" "Developmental protein" "Craniosynostosis, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Fibroblasts: 22.3;Peritubular cells: 30.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "ASC TERT1: 97.2;U-2197: 177.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029135, HPA029136" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 18: U-2197 - ECM organization" "Cluster 33: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "HPA029135: AB_10602070, HPA029136: AB_10601794" "unprognostic (8.78e-2)" "unprognostic (6.55e-2)" "unprognostic (7.17e-2)" "unprognostic (1.10e-1)" "unprognostic (2.14e-2)" "unprognostic (2.28e-2)" "unprognostic (2.55e-2)" "unprognostic (5.33e-3)" "unprognostic (6.41e-2)" "unprognostic (6.55e-2)" "unprognostic (1.05e-1)" "unprognostic (2.97e-2)" "unprognostic (9.12e-3)" "unprognostic (1.36e-2)" "unprognostic (2.38e-1)" "unprognostic (6.37e-2)" "unprognostic (1.46e-3)" 9.6 6.1 8.6 13.2 9.0 0.8 7.8 10.9 9.6 45.9 6.1 59.7 7.0 52.6 14.1 19.9 14.5 26.9 12.3 8.5 15.2 7.3 4.1 10.6 4.5 8.7 8.7 10.8 2.9 5.7 3.4 27.6 9.5 38.7 15.9 3.9 3.9 55.7 6.1 4.8 10.8 75.0 9.2 2.2 11.6 5.1 9.7 3.2 32.6 10.4 4.1 46.7 14.7 11.5 15.6 6.1 21.6 15.3 32.3 97.2 19.8 44.9 77.4 38.6 39.7 13.4 7.3 3.1 13.6 72.3 19.3 5.5 22.7 16.4 45.6 11.6 10.5 11.3 9.4 10.6 19.8 5.9 1.6 36.5 18.6 48.1 44.7 18.7 20.3 6.6 17.6 9.3 43.4 13.2 5.2 6.3 8.1 10.3 8.2 5.7 31.7 4.7 26.8 10.7 11.2 7.6 22.5 10.6 11.6 26.8 9.7 6.8 27.4 59.6 18.5 177.4 26.6 8.0 9.3 7.6 33.5 12.5 30.2 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.1 0.0 0.1 0.1 0.2 0.0 0.0 8.6 9.0 10.9 9.6 8.5 15.2 8.7 8.7 9.5 9.2 9.7 11.5 2.9 12.8 5.0 6.8 0.7 4.1 1.6 2.0 5.7 2.5 4.0 3.0 3.4 1.5 1.6 0.0 2.1 11.5 1.7 2.4 0.0 3.4 2.4 6.5 15.5 2.6 1.2 4.8 13.0 2.9 10.7 22.3 1.1 6.2 0.0 3.7 4.6 3.4 4.2 1.7 12.3 1.4 2.0 0.8 3.1 2.5 19.9 1.4 5.4 11.2 7.7 4.4 0.0 8.0 5.3 2.6 0.1 30.5 0.5 3.5 0.6 6.1 5.3 0.9 0.0 17.2 14.5 6.6 7.8 4.1 5.1 13.7 0.8 4.0 1.6 1.8 RAB3GAP2 "DKFZP434D245, KIAA0839, RAB3-GAP150, SPG69" ENSG00000118873 "RAB3 GTPase activating non-catalytic protein subunit 2" Q9H2M9 1 220148293-220272453 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "GTPase activation" "Cataract, Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026273, HPA027299" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA026273: AB_1856007, HPA027299: AB_1856008" "prognostic unfavorable (3.05e-4)" "unprognostic (2.80e-3)" "unprognostic (1.76e-2)" "unprognostic (6.07e-2)" "unprognostic (5.20e-2)" "unprognostic (1.69e-1)" "unprognostic (2.40e-2)" "unprognostic (7.00e-2)" "unprognostic (4.61e-2)" "unprognostic (1.75e-1)" "unprognostic (4.63e-2)" "unprognostic (2.13e-1)" "unprognostic (7.75e-2)" "unprognostic (1.27e-1)" "unprognostic (1.17e-1)" "unprognostic (3.99e-2)" "unprognostic (1.56e-1)" 10.1 9.0 6.3 9.6 6.7 10.2 11.2 11.4 7.8 8.7 23.5 8.8 7.8 9.4 8.4 9.0 7.0 7.9 9.3 7.3 9.3 11.7 10.0 8.6 12.6 6.7 6.9 9.6 8.6 18.6 6.2 11.5 9.0 8.5 8.3 18.1 9.2 7.9 8.7 7.9 7.8 9.3 5.7 9.2 9.4 6.6 7.5 13.1 12.8 12.2 14.4 9.1 6.0 9.1 21.3 15.8 18.9 14.3 21.2 25.1 21.4 21.4 20.3 18.9 22.2 14.7 17.3 26.4 14.8 20.9 14.3 19.9 19.8 16.4 21.8 22.1 12.9 20.6 21.5 13.8 27.9 29.8 20.3 20.0 18.4 18.5 28.5 21.2 17.6 11.4 36.2 16.6 21.6 6.0 23.0 10.5 40.8 11.4 9.3 12.5 26.0 23.7 16.1 17.3 18.8 22.7 22.2 21.4 35.3 20.3 22.4 28.0 25.7 20.6 9.6 14.4 23.2 14.6 19.2 22.8 17.7 24.6 24.8 10.0 2.8 5.6 4.8 3.6 5.9 4.8 4.7 6.2 3.8 3.8 4.1 4.9 1.8 2.8 3.9 2.4 6.0 3.3 6.3 6.7 11.4 7.8 7.3 9.3 6.7 6.9 9.0 5.7 7.5 9.1 28.5 41.7 21.9 60.7 30.4 11.6 13.6 15.8 17.6 57.9 18.9 16.3 34.8 32.9 23.4 25.8 68.8 18.5 30.6 23.8 5.9 17.4 4.3 21.4 27.7 22.3 35.4 18.7 106.8 16.7 13.5 23.4 20.4 28.5 19.6 40.8 28.9 24.2 25.4 42.1 105.1 22.1 16.2 29.0 9.4 2.8 18.0 22.2 14.2 68.4 25.2 39.8 26.8 82.0 81.5 21.7 14.2 25.9 24.7 21.0 19.4 14.9 17.2 50.5 6.6 24.1 20.4 17.7 13.6 17.5 9.8 23.1 27.1 23.6 19.3 13.2 RAB8A "MEL, RAB8" ENSG00000167461 "RAB8A, member RAS oncogene family" P61006 19 16111889-16134234 "Predicted intracellular proteins" "Autophagy, Cilium biogenesis/degradation, Protein transport, Transport" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041945 Approved "Nucleoplasm,Plasma membrane" No No 4800000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 9: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "HPA041945: " "unprognostic (1.10e-1)" "unprognostic (3.95e-3)" "unprognostic (1.98e-2)" "unprognostic (2.59e-1)" "unprognostic (1.63e-1)" "unprognostic (1.66e-1)" "unprognostic (1.19e-1)" "unprognostic (2.11e-1)" "unprognostic (2.57e-1)" "unprognostic (1.14e-2)" "unprognostic (2.52e-3)" "unprognostic (1.29e-2)" "prognostic unfavorable (6.56e-5)" "unprognostic (6.60e-2)" "unprognostic (7.25e-2)" "prognostic favorable (1.71e-4)" "unprognostic (9.99e-2)" 21.3 24.5 17.4 40.4 17.5 61.3 18.7 19.5 17.6 24.6 20.7 37.4 58.5 18.5 18.9 25.9 27.8 22.0 11.5 17.2 19.1 20.8 51.5 28.6 44.3 21.1 19.5 21.5 23.4 17.7 15.3 25.0 21.6 21.7 32.8 8.7 30.7 21.2 7.0 27.5 58.7 22.8 20.3 40.4 32.4 15.4 19.0 34.3 16.3 8.1 45.1 25.9 21.2 23.3 94.2 62.6 50.5 43.0 42.7 36.7 77.9 56.0 48.8 74.2 76.8 76.1 105.7 66.1 61.9 58.6 63.5 60.6 71.2 69.1 50.9 132.6 39.9 135.9 57.1 75.6 46.7 119.4 129.3 36.6 37.6 69.5 32.1 38.9 63.5 65.0 64.4 97.0 63.4 111.6 100.1 113.7 63.3 114.3 100.5 111.6 56.2 115.6 58.2 71.9 46.9 45.3 56.6 68.0 35.9 34.2 53.8 44.2 61.7 61.4 39.2 119.2 96.6 51.4 113.4 97.3 58.7 121.5 67.0 244.5 278.6 315.0 164.3 387.5 145.7 190.5 143.3 147.5 247.5 190.0 112.5 131.7 292.2 225.9 485.1 177.8 150.9 514.1 17.4 17.5 19.5 17.6 17.2 19.1 21.1 19.5 21.6 20.3 19.0 23.3 47.2 25.6 29.1 2.3 70.2 47.7 47.4 53.5 31.3 15.2 37.0 34.7 3.0 17.2 35.7 31.3 14.6 95.7 97.9 115.9 82.2 70.7 31.0 33.7 29.7 37.3 30.4 47.5 4.2 51.5 98.6 36.3 29.6 45.0 48.7 36.2 26.0 50.3 88.9 6.7 3.5 55.3 48.8 50.6 81.5 19.0 27.7 100.9 33.8 2.8 124.8 34.9 131.8 3.0 8.8 76.8 90.0 24.8 96.5 30.7 130.7 62.6 35.4 13.9 32.9 22.0 38.1 33.3 23.4 30.4 52.6 79.6 64.8 43.4 52.0 38.4 RAD52 ENSG00000002016 "RAD52 homolog, DNA repair protein" P43351 12 911736-990053 "Cancer-related genes, Predicted intracellular proteins" "DNA damage, DNA recombination, DNA repair" DNA-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 34.9;Excitatory neurons: 38.0;Inhibitory neurons: 48.8;Microglial cells: 23.4;Oligodendrocyte precursor cells: 30.2;Oligodendrocytes: 54.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA028957 Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nuclear speckles" "Plasma membrane" "HPA028957: AB_2672842" "unprognostic (4.53e-1)" "unprognostic (8.08e-3)" "unprognostic (4.68e-2)" "unprognostic (5.27e-2)" "unprognostic (7.37e-2)" "unprognostic (1.42e-2)" "unprognostic (1.82e-3)" "unprognostic (1.88e-1)" "unprognostic (2.80e-2)" "unprognostic (8.43e-2)" "unprognostic (1.03e-2)" "unprognostic (3.27e-1)" "prognostic unfavorable (2.22e-6)" "unprognostic (1.54e-1)" "unprognostic (1.61e-1)" "unprognostic (1.68e-1)" "unprognostic (3.74e-2)" 4.9 4.7 5.9 5.0 8.2 3.6 6.0 7.8 8.4 8.8 5.1 7.2 5.8 7.3 8.4 4.7 6.6 4.2 4.7 7.1 7.0 7.6 6.4 4.0 6.3 7.2 7.3 10.8 6.6 4.9 5.2 5.4 7.6 6.2 7.0 6.8 4.4 6.0 12.3 9.8 6.6 6.1 5.3 6.0 5.5 4.4 7.8 7.0 8.3 6.8 5.9 6.1 5.8 13.7 4.0 15.2 11.6 13.8 12.1 9.7 12.7 7.9 7.5 9.0 8.7 14.8 14.3 12.8 2.4 8.2 7.4 12.0 9.4 5.4 7.7 17.7 8.2 14.6 16.2 10.0 7.0 15.6 4.2 5.5 9.4 9.1 28.3 17.6 7.4 12.4 9.8 7.5 8.6 8.7 10.8 15.7 15.4 10.0 9.9 10.8 11.6 4.8 9.4 7.1 4.3 5.0 10.3 10.8 6.0 16.8 10.2 7.5 7.4 12.3 14.6 9.8 8.6 2.7 4.6 13.5 6.3 6.9 4.5 7.0 2.1 1.5 2.9 1.9 3.5 2.9 3.0 2.5 2.7 4.0 3.3 3.2 2.0 2.6 2.5 6.0 2.9 1.0 5.9 8.2 7.8 8.4 7.1 7.0 7.2 7.3 7.6 5.3 7.8 13.7 2.5 3.2 5.9 34.9 3.4 1.8 1.4 1.7 4.0 4.2 2.7 2.7 3.6 2.8 3.2 3.7 2.1 4.8 4.5 5.9 1.9 2.3 4.0 2.3 4.5 3.4 1.8 4.2 38.0 1.6 2.8 3.3 5.1 2.6 5.7 4.5 0.7 2.6 2.5 3.3 48.8 2.0 0.0 1.0 2.9 7.5 0.6 2.6 0.0 23.4 2.8 1.4 1.0 30.2 54.5 0.9 3.4 0.7 2.3 1.6 3.9 1.8 1.7 2.6 6.6 4.2 3.9 4.0 4.7 1.9 1.0 2.1 2.6 2.2 3.3 0.8 RAET1G ULBP5 ENSG00000203722 "Retinoic acid early transcript 1G" Q6H3X3 6 149916878-149923121 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 8.4;esophagus: 15.1" "Cell type enhanced" "Detected in some" "Basal respiratory cells: 42.9;Club cells: 14.8;Ionocytes: 12.2;Respiratory ciliated cells: 23.3;Squamous epithelial cells: 8.9;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.5;head and neck cancer: 4.7;lung cancer: 1.2;thyroid cancer: 1.5;urothelial cancer: 4.2" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HeLa: 29.5;hTCEpi: 22.6;SiHa: 11.9;U-87 MG: 9.3" "HPA062673, HPA066741" Supported "Vesicles,Plasma membrane" "Secreted - unknown location" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 20: HeLa - Mitochondria" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "HPA062673: , HPA066741: " "unprognostic (4.46e-3)" "unprognostic (4.92e-2)" "unprognostic (1.95e-1)" "unprognostic (1.21e-1)" "unprognostic (2.87e-3)" "unprognostic (1.49e-1)" "unprognostic (4.61e-3)" "prognostic unfavorable (5.35e-4)" "unprognostic (3.05e-1)" "unprognostic (1.57e-1)" "unprognostic (1.43e-1)" "unprognostic (1.38e-2)" "unprognostic (1.33e-1)" "unprognostic (1.49e-2)" "unprognostic (2.48e-1)" "unprognostic (8.85e-2)" "unprognostic (9.11e-2)" 2.8 8.4 0.4 0.4 0.3 0.0 0.6 0.0 0.4 4.1 0.0 0.2 0.1 0.3 0.7 15.1 0.6 0.7 0.6 0.4 0.3 0.9 0.1 0.5 0.1 0.3 0.6 0.7 0.1 0.2 0.3 0.1 0.1 0.7 0.1 0.1 3.7 1.0 0.2 2.7 0.2 0.6 0.0 0.1 0.4 0.3 0.7 0.0 0.4 0.1 1.1 1.8 6.0 0.0 1.0 1.4 0.0 1.7 2.3 1.7 0.0 0.8 3.0 1.3 1.9 0.0 1.5 0.0 0.6 1.7 1.4 2.7 0.9 5.3 1.1 0.3 1.6 0.5 29.5 0.0 0.7 0.0 0.0 3.3 22.6 3.5 1.7 1.5 0.3 0.7 0.3 0.2 0.6 1.3 0.0 0.0 0.0 0.3 2.3 0.0 0.0 0.0 1.0 3.2 0.3 0.3 11.9 0.5 0.0 0.1 0.4 0.4 1.6 0.6 0.5 1.6 0.8 0.0 0.0 0.0 9.3 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.4 0.4 0.3 0.3 0.6 0.1 0.0 0.7 0.0 1.4 0.0 0.0 0.0 0.0 3.1 5.1 42.9 2.8 0.0 0.4 0.4 0.1 1.5 14.8 0.0 0.0 0.0 0.2 0.1 0.0 0.2 0.1 0.4 0.1 1.3 0.0 0.0 0.0 1.3 0.0 1.9 0.0 0.1 0.0 0.0 0.7 0.0 0.1 0.0 0.0 0.0 12.2 0.0 0.7 0.1 0.9 0.0 3.6 0.0 0.0 0.8 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.4 0.0 0.0 23.3 0.0 0.0 0.2 1.1 0.0 0.3 8.9 1.7 0.1 0.3 0.5 0.0 8.1 RAET1L ENSG00000155918 "Retinoic acid early transcript 1L" Q5VY80 6 150018334-150025532 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "esophagus: 58.1;vagina: 17.3" "Cell type enhanced" "Detected in some" "Basal keratinocytes: 6.4;Basal prostatic cells: 11.3;Basal respiratory cells: 6.4;Prostatic glandular cells: 7.1;Squamous epithelial cells: 7.2;Suprabasal keratinocytes: 17.0;Urothelial cells: 8.1" "Group enriched" "Detected in many" 4 "cervical cancer: 4.8;head and neck cancer: 10.1;lung cancer: 4.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HaCaT: 14.3" HPA066741 Supported "Vesicles,Plasma membrane" NA NA "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Vesicles, Plasma membrane" "HPA066741: " "unprognostic (1.80e-1)" "unprognostic (1.63e-1)" "unprognostic (2.15e-1)" "unprognostic (1.84e-1)" "unprognostic (4.24e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (4.09e-4)" "unprognostic (8.34e-2)" "unprognostic (1.37e-1)" "unprognostic (2.26e-2)" "unprognostic (7.48e-2)" "unprognostic (1.46e-2)" "unprognostic (2.49e-1)" "unprognostic (1.29e-1)" "unprognostic (5.14e-2)" "unprognostic (7.43e-3)" 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.1 8.1 0.0 0.0 0.0 0.0 0.0 58.1 0.0 0.1 0.0 0.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.7 0.0 0.1 5.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 5.2 0.3 17.3 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.8 0.0 1.2 0.0 0.7 14.3 0.3 0.4 0.0 0.5 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 2.4 0.0 0.0 0.0 2.6 0.7 0.0 0.0 1.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 1.7 0.2 0.4 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.4 11.3 6.4 1.2 0.0 0.4 0.3 0.0 0.0 2.9 0.0 0.0 0.0 0.0 1.0 0.0 2.8 0.8 0.5 0.1 0.2 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 7.1 0.0 0.2 0.9 0.0 0.0 0.0 0.4 0.0 0.1 7.2 17.0 0.0 0.0 0.0 0.1 8.1 RAF1 "c-Raf, CRAF, Raf-1" ENSG00000132155 "Raf-1 proto-oncogene, serine/threonine kinase" P04049 3 12583601-12664125 "Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Predicted intracellular proteins, RAS pathway related proteins" "Kinase, Serine/threonine-protein kinase, Transferase" "Cancer-related genes, Cardiomyopathy, Deafness, Disease variant, FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 175.1" "Lineage enriched" "Detected in all" 5 "granulocytes: 175.1" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002639, HPA002640, CAB019291" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 59: Non-specific - Translation" "Cluster 28: BEWO - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cytosol" "CAB019291: , HPA002639: , HPA002640: AB_1856047" "unprognostic (6.33e-2)" "unprognostic (1.29e-1)" "unprognostic (5.92e-2)" "unprognostic (2.17e-3)" "unprognostic (6.51e-3)" "unprognostic (7.66e-3)" "unprognostic (2.66e-3)" "unprognostic (1.53e-2)" "unprognostic (2.72e-1)" "unprognostic (7.66e-2)" "unprognostic (2.92e-2)" "unprognostic (1.29e-2)" "unprognostic (2.79e-2)" "unprognostic (1.79e-1)" "unprognostic (1.27e-1)" "unprognostic (2.64e-2)" "unprognostic (2.36e-2)" 42.4 34.2 36.7 33.8 37.9 77.4 39.2 42.6 37.4 47.6 40.4 46.8 40.5 45.6 34.0 55.5 43.2 31.0 89.6 36.9 35.8 46.7 68.9 44.7 36.3 38.3 36.9 52.0 50.6 63.6 28.3 39.1 37.0 41.9 42.0 37.4 39.6 38.0 194.9 56.0 43.4 45.5 36.7 48.3 55.5 26.8 38.1 52.8 48.8 122.5 47.7 46.1 46.2 39.8 49.9 57.9 85.5 66.6 74.3 59.6 168.0 73.9 129.1 100.1 112.5 46.6 41.3 52.7 34.6 120.1 51.6 31.9 93.4 67.5 103.8 91.4 70.2 72.0 69.4 42.9 74.2 70.1 64.7 55.3 67.8 102.3 82.0 67.6 73.1 78.2 52.6 136.0 98.3 88.6 91.1 47.8 86.5 64.0 76.4 72.6 75.7 66.4 60.9 76.9 26.1 56.2 61.1 59.8 40.9 66.1 99.1 91.5 51.1 65.6 62.5 55.7 85.0 103.3 178.4 112.3 57.2 80.4 73.9 40.4 32.7 62.5 22.3 32.6 22.5 19.5 21.9 22.3 30.3 20.4 21.9 22.8 175.1 29.8 34.2 13.5 28.3 28.2 36.7 37.9 42.6 37.4 36.9 35.8 38.3 36.9 37.0 36.7 38.1 39.8 28.5 22.4 37.6 47.7 36.1 34.4 35.2 22.1 27.9 56.7 27.5 22.6 29.0 35.8 25.7 27.6 66.7 40.0 41.5 31.3 13.7 25.6 8.8 33.2 37.1 32.7 29.3 46.7 46.1 37.0 46.8 32.3 27.5 43.8 34.2 78.7 36.0 41.2 28.6 43.7 52.9 31.0 30.5 39.3 43.4 4.6 39.1 34.7 26.6 44.0 49.5 31.9 51.5 65.4 64.0 35.5 29.9 41.3 43.3 46.9 47.3 20.1 31.2 81.9 32.9 56.2 39.1 28.3 33.6 31.8 43.5 62.3 40.8 35.6 31.2 47.1 RALA RAL ENSG00000006451 "RAS like proto-oncogene A" P11233 7 39623565-39708120 "Enzymes, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Exocytosis" Hydrolase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Langerhans cells: 292.4;Pancreatic endocrine cells: 411.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "HUVEC TERT2: 302.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA047037, HPA065232" Approved Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" "Focal adhesion sites" "HPA047037: , HPA065232: AB_2685440" "unprognostic (1.20e-3)" "unprognostic (1.03e-2)" "unprognostic (2.91e-1)" "unprognostic (7.73e-3)" "unprognostic (1.98e-2)" "unprognostic (9.14e-2)" "prognostic unfavorable (5.32e-5)" "unprognostic (7.71e-2)" "unprognostic (2.17e-1)" "prognostic favorable (7.46e-4)" "prognostic unfavorable (6.30e-4)" "unprognostic (3.32e-1)" "unprognostic (4.95e-3)" "unprognostic (5.38e-2)" "unprognostic (7.15e-2)" "unprognostic (2.79e-1)" "unprognostic (2.95e-2)" 27.8 32.1 32.4 20.7 35.5 7.4 23.8 35.8 37.3 23.0 30.2 30.9 32.6 20.4 20.1 54.0 19.6 26.8 17.6 33.7 34.3 20.6 21.4 41.8 21.4 37.0 35.7 22.2 16.0 22.6 10.5 32.5 36.4 15.4 31.6 13.0 19.8 15.8 25.8 26.9 30.9 21.1 37.7 18.8 33.8 12.7 34.9 25.5 17.4 19.1 35.2 23.5 22.0 39.8 81.0 18.3 44.1 38.6 81.7 67.6 30.0 69.7 99.7 61.8 67.9 46.1 39.0 41.5 25.5 54.1 58.1 81.5 62.5 45.0 105.5 40.2 29.6 32.4 28.1 34.1 132.1 56.9 43.8 53.7 54.0 110.0 155.4 76.7 302.4 39.7 65.9 27.0 63.2 26.3 40.3 66.7 123.0 88.0 35.9 49.4 40.2 36.3 63.1 37.3 78.0 75.6 42.8 67.7 49.4 78.7 63.5 60.9 98.0 36.4 32.4 46.3 50.7 47.6 39.1 50.3 40.5 58.0 67.2 38.3 13.5 15.7 12.5 15.6 15.7 15.8 20.1 16.2 22.6 18.0 25.6 22.9 6.1 23.2 12.6 14.5 28.1 15.9 32.4 35.5 35.8 37.3 33.7 34.3 37.0 35.7 36.4 37.7 34.9 39.8 66.5 83.3 38.1 25.5 40.5 90.1 37.3 75.1 41.5 14.6 41.3 63.5 37.3 40.0 50.3 23.9 6.2 52.1 28.4 80.1 21.5 165.4 98.2 56.5 64.8 121.5 47.8 35.1 47.6 122.0 92.5 52.4 42.3 99.9 31.7 41.8 75.0 27.8 101.9 11.8 48.4 53.1 144.5 33.0 292.4 17.4 47.8 73.0 30.2 44.0 97.0 37.3 23.7 39.2 37.0 411.0 73.8 69.6 48.6 61.0 70.8 38.6 36.6 16.6 32.9 26.5 131.9 59.1 71.6 113.4 109.4 62.0 37.0 53.9 58.7 64.5 RALGAPA2 "AS250, C20orf74, dJ1049G11.4, KIAA1272, RapGAPalpha2" ENSG00000188559 "Ral GTPase activating protein catalytic subunit alpha 2" Q2PPJ7 20 20389530-20712644 "Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Astrocytes: 212.2;Microglial cells: 145.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RT4: 91.5;SCLC-21H: 51.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA042707, HPA043622" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 15: RT4 - Unknown function" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA042707: AB_2678124, HPA043622: AB_2678585" "unprognostic (7.40e-2)" "unprognostic (1.71e-1)" "unprognostic (1.69e-2)" "unprognostic (1.09e-2)" "unprognostic (2.36e-1)" "unprognostic (3.34e-2)" "unprognostic (3.36e-1)" "unprognostic (3.29e-2)" "unprognostic (1.95e-1)" "unprognostic (3.56e-2)" "unprognostic (1.74e-1)" "unprognostic (8.23e-2)" "prognostic favorable (3.77e-5)" "unprognostic (6.52e-2)" "unprognostic (1.54e-1)" "unprognostic (3.48e-1)" "unprognostic (5.33e-2)" 16.7 6.5 4.6 6.1 6.2 20.6 15.0 10.8 7.6 9.6 5.7 12.2 10.3 8.7 3.7 8.8 10.8 11.3 7.9 4.3 4.8 10.2 27.3 25.2 6.4 6.9 8.0 7.4 17.0 13.1 14.5 17.6 7.5 13.1 12.6 13.4 15.1 5.5 34.4 16.9 10.5 7.0 2.8 7.5 18.3 10.1 13.1 8.0 21.1 21.0 5.4 12.6 8.4 9.5 7.0 4.4 9.2 4.7 5.1 3.6 10.1 1.8 2.0 2.1 3.0 3.8 9.5 3.2 6.1 3.0 10.6 7.1 9.4 8.6 4.0 16.1 4.6 11.1 2.5 6.7 1.8 14.0 6.4 3.1 6.4 3.5 1.7 3.9 13.1 14.9 2.2 6.0 3.8 4.9 5.6 18.5 3.8 22.8 3.9 7.6 6.2 4.5 7.4 91.5 51.4 4.5 6.9 5.2 6.1 8.9 3.6 13.7 3.3 3.7 3.6 2.7 2.6 3.5 2.6 1.8 3.1 9.1 5.4 4.4 1.1 3.6 0.8 0.4 1.2 1.1 0.5 0.8 0.5 0.8 1.0 1.1 4.4 2.7 1.0 1.2 1.0 0.3 4.6 6.2 10.8 7.6 4.3 4.8 6.9 8.0 7.5 2.8 13.1 9.5 90.7 6.4 42.5 212.2 9.7 10.6 10.1 25.9 6.8 47.8 13.5 7.7 9.1 41.5 27.0 14.7 27.1 10.6 14.6 24.7 1.9 23.9 28.9 61.0 16.4 80.1 24.6 10.7 87.3 24.9 4.9 7.6 51.5 123.0 8.2 97.3 67.1 47.4 12.8 52.2 122.0 20.7 40.7 18.3 10.3 7.3 1.8 13.0 8.8 145.2 18.2 8.8 10.3 122.2 111.1 19.5 21.0 6.8 4.8 20.5 20.6 12.5 43.1 13.5 13.1 16.4 9.7 12.3 11.1 15.3 16.6 11.2 14.3 19.7 30.6 25.0 RAPGEF2 "DKFZP586O1422, KIAA0313, PDZ-GEF1, PDZGEF1, RA-GEF" ENSG00000109756 "Rap guanine nucleotide exchange factor 2" Q9Y4G8 4 159103013-159360174 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Differentiation, Neurogenesis" "Developmental protein, GTPase activation, Guanine-nucleotide releasing factor" Epilepsy "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Excitatory neurons: 456.2;Inhibitory neurons: 264.1;Microglial cells: 238.9;Oligodendrocyte precursor cells: 199.0;Oligodendrocytes: 236.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 5.9" "Group enriched" "Detected in many" 5 "granulocytes: 5.9;NK-cells: 3.3" "Cell line enhanced" "Detected in many" "HMC-1: 104.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA068798 Supported "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA068798: " "unprognostic (4.88e-2)" "unprognostic (7.42e-2)" "unprognostic (1.67e-2)" "unprognostic (7.79e-3)" "unprognostic (8.16e-2)" "unprognostic (4.71e-3)" "unprognostic (4.20e-3)" "unprognostic (2.33e-1)" "unprognostic (2.17e-1)" "unprognostic (2.65e-2)" "unprognostic (9.71e-2)" "unprognostic (1.07e-1)" "prognostic favorable (1.76e-7)" "unprognostic (2.29e-1)" "unprognostic (2.07e-1)" "unprognostic (2.01e-2)" "unprognostic (1.78e-1)" 22.7 9.4 8.7 13.4 19.8 87.5 24.1 4.1 32.1 16.7 0.0 21.8 15.9 16.1 9.8 13.8 14.0 20.1 23.2 27.4 0.3 22.7 30.5 26.6 11.9 0.0 0.7 13.5 19.5 23.5 15.3 38.5 0.3 12.2 20.8 35.1 25.3 12.6 21.7 17.5 17.0 19.7 0.6 29.7 19.3 9.8 6.0 17.5 39.5 31.4 11.5 14.8 11.8 18.6 8.9 11.9 55.4 17.2 21.4 23.9 84.9 17.0 21.3 15.2 10.9 36.7 19.4 50.7 6.1 17.0 22.0 8.0 19.1 21.8 18.0 8.6 13.2 79.0 25.3 21.4 15.5 9.7 104.5 14.1 12.1 36.5 12.9 32.0 44.1 20.7 17.6 46.0 19.0 15.6 24.1 1.5 23.7 10.4 11.8 19.7 14.0 2.0 13.6 20.2 15.7 21.0 24.9 12.1 20.0 26.5 6.0 6.3 47.0 23.9 25.2 30.7 14.2 51.0 32.9 0.8 28.3 4.1 14.8 2.2 1.0 0.7 0.5 0.5 0.6 0.2 0.4 0.3 0.5 0.2 0.6 0.3 5.9 3.3 0.6 1.0 1.0 0.3 8.7 19.8 4.1 32.1 27.4 0.3 0.0 0.7 0.3 0.6 6.0 18.6 66.7 57.7 30.1 110.7 12.9 20.4 11.2 7.5 9.6 19.7 23.5 11.9 39.0 11.5 13.8 7.3 41.7 11.1 20.2 24.8 0.0 9.2 5.3 43.5 19.5 49.2 14.4 38.9 456.2 12.6 9.6 16.9 7.7 59.2 51.8 22.9 32.2 30.5 10.8 33.7 264.1 12.0 2.0 24.6 20.1 5.3 7.8 29.5 33.8 238.9 15.6 30.2 2.1 199.0 236.2 22.1 17.7 8.6 40.5 17.6 7.1 8.7 18.7 22.4 52.6 28.1 37.2 3.5 8.9 10.7 20.0 5.9 12.9 7.2 7.9 15.1 RASAL2 nGAP ENSG00000075391 "RAS protein activator like 2" Q9UJF2 1 178094104-178484147 "Plasma proteins, Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "retina: 28.9" "Cell type enhanced" "Detected in many" "Excitatory neurons: 505.8;Inhibitory neurons: 398.4;Microglial cells: 271.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-HME1: 54.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018805, HPA020453" Enhanced Approved "Plasma membrane,Focal adhesion sites" NA Yes "Cluster 77: Retina - Visual perception" "Cluster 30: Epithelial cell lines - Translation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Focal adhesion sites" "HPA018805: AB_1856085, HPA020453: AB_1856086" "unprognostic (5.55e-3)" "unprognostic (6.49e-2)" "unprognostic (2.65e-1)" "unprognostic (6.33e-2)" "unprognostic (3.40e-2)" "unprognostic (5.59e-2)" "unprognostic (5.91e-2)" "unprognostic (1.72e-2)" "unprognostic (2.91e-1)" "unprognostic (2.92e-2)" "unprognostic (3.16e-3)" "unprognostic (2.03e-1)" "unprognostic (1.06e-2)" "unprognostic (4.98e-2)" "unprognostic (2.45e-1)" "unprognostic (8.36e-2)" "prognostic unfavorable (2.05e-4)" 10.3 3.6 1.7 2.8 3.2 0.6 8.0 0.0 7.4 7.3 0.1 4.2 2.7 6.1 3.6 17.0 5.5 7.5 13.6 4.3 0.8 5.8 3.0 9.4 1.8 0.0 1.0 3.6 4.6 4.6 5.9 9.4 0.0 5.0 4.4 28.9 6.6 4.4 4.6 7.0 3.4 6.6 0.0 3.2 3.7 8.9 5.1 1.8 5.3 10.0 2.9 5.0 10.5 2.4 30.9 8.9 12.1 4.2 8.6 11.6 17.3 13.2 13.6 11.7 8.5 14.8 15.6 0.0 23.0 13.2 19.7 25.2 10.2 23.0 10.7 0.0 5.0 0.0 9.8 7.1 10.0 4.7 0.5 35.1 5.2 13.4 54.1 13.7 10.3 0.0 1.0 0.0 16.5 3.2 0.0 4.2 10.1 6.4 1.8 0.1 5.2 0.0 7.2 3.6 8.8 4.4 10.9 9.5 9.0 10.8 10.4 5.5 18.9 15.1 15.7 17.2 21.0 6.5 0.1 0.1 13.3 2.4 11.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 1.7 3.2 0.0 7.4 4.3 0.8 0.0 1.0 0.0 0.0 5.1 2.4 99.8 76.9 12.9 47.3 1.0 15.9 10.0 15.7 8.0 50.7 17.8 11.7 37.4 17.2 18.2 16.5 152.2 15.0 1.0 9.0 5.9 21.8 17.4 33.6 43.0 66.2 34.1 0.0 505.8 12.5 16.4 18.4 17.9 27.6 7.6 19.0 35.3 6.7 16.8 84.1 398.4 15.7 6.1 4.5 21.6 7.3 19.6 16.5 3.6 271.7 8.5 24.7 0.0 154.3 101.3 33.6 5.2 23.0 2.9 32.6 4.9 6.6 34.7 175.5 65.7 22.7 56.9 40.5 34.5 17.8 24.2 41.9 2.3 8.3 12.6 38.2 RASAL3 FLJ21438 ENSG00000105122 "RAS protein activator like 3" Q86YV0 19 15451624-15464544 "Predicted intracellular proteins, RAS pathway related proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "bone marrow: 23.5;intestine: 19.8;lung: 10.6;lymphoid tissue: 39.4" "Cell type enhanced" "Detected in many" "B-cells: 39.4;dendritic cells: 70.9;granulocytes: 39.3;NK-cells: 139.0;T-cells: 76.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in some" "HDLM-2: 30.6;HEL: 25.5;HMC-1: 46.7;Karpas-707: 52.5;NB-4: 27.8;RPMI-8226: 23.5;TIME: 35.5;U-937: 34.1" "Low region specificity" "Detected in some" "Low region specificity" "Detected in many" HPA043417 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "HPA043417: AB_2678473" "unprognostic (2.72e-2)" "prognostic favorable (8.75e-4)" "unprognostic (3.27e-2)" "prognostic favorable (3.58e-5)" "unprognostic (2.31e-1)" "prognostic favorable (3.07e-4)" "unprognostic (1.82e-2)" "unprognostic (6.21e-3)" "unprognostic (7.40e-3)" "unprognostic (1.02e-1)" "unprognostic (3.49e-2)" "unprognostic (3.32e-1)" "prognostic unfavorable (1.16e-6)" "unprognostic (2.98e-1)" "unprognostic (1.90e-2)" "unprognostic (1.24e-2)" "unprognostic (1.69e-2)" 3.7 2.6 2.8 17.3 2.9 23.5 1.9 3.1 3.6 1.8 2.9 4.2 4.5 1.5 0.7 2.8 2.2 3.6 1.4 2.9 3.2 3.7 3.6 10.6 32.8 4.2 3.3 0.9 1.4 1.2 1.5 1.0 3.9 2.8 2.3 0.1 3.5 0.9 0.7 1.5 19.8 1.2 4.1 39.4 5.4 0.5 4.2 23.8 3.8 0.4 19.4 4.2 2.3 5.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 6.3 0.2 0.0 0.0 0.1 0.0 0.0 0.0 30.6 0.0 25.5 0.0 0.0 0.4 20.4 46.7 0.1 0.0 0.0 0.0 0.0 0.2 8.0 0.0 52.5 0.0 0.4 10.9 27.8 0.0 0.0 0.0 3.0 0.0 23.5 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 8.7 35.5 0.0 0.0 0.0 0.0 0.4 10.1 15.1 0.0 34.1 0.1 6.4 2.3 12.9 18.4 4.7 10.7 3.1 11.7 20.4 3.4 3.5 9.7 11.8 3.4 12.4 12.8 4.2 9.2 5.5 2.8 2.9 3.1 3.6 2.9 3.2 4.2 3.3 3.9 4.1 4.2 5.2 4.1 3.2 5.6 0.0 39.4 0.3 0.0 0.3 0.0 0.0 2.0 2.2 2.5 2.8 1.4 0.0 0.0 0.2 70.9 0.0 0.0 0.2 0.7 5.4 0.4 5.4 0.0 7.4 0.1 0.6 0.2 1.0 2.6 0.4 39.3 0.0 3.9 4.6 11.3 0.0 0.1 0.0 0.0 11.6 3.5 1.7 0.0 17.2 0.0 13.1 14.2 0.1 139.0 0.5 0.1 0.2 0.0 1.2 23.7 0.2 0.0 1.5 5.7 0.1 0.0 0.5 1.5 0.4 0.6 0.3 0.6 0.4 76.7 1.0 0.2 0.1 RASD1 "AGS1, DEXRAS1" ENSG00000108551 "Ras related dexamethasone induced 1" Q9Y272 17 17494437-17496395 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "pituitary gland: 371.9" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 425.1;Muller glia cells: 375.3;Peritubular cells: 469.8;Sertoli cells: 565.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 46 "plasmacytoid DC: 160.1" "Lineage enriched" "Detected in many" 46 "dendritic cells: 160.1" "Group enriched" "Detected in some" 4 "ASC diff: 70.2;REH: 71.0" "Group enriched" "Detected in all" 5 "basal ganglia: 75.6;hippocampal formation: 54.9;thalamus: 53.2" "Low region specificity" "Detected in all" HPA047896 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "HPA047896: AB_10960535" "unprognostic (1.59e-1)" "unprognostic (1.32e-1)" "unprognostic (3.28e-2)" "unprognostic (3.31e-2)" "unprognostic (6.40e-2)" "unprognostic (8.13e-2)" "unprognostic (8.65e-2)" "unprognostic (7.60e-2)" "unprognostic (5.50e-2)" "unprognostic (2.11e-1)" "unprognostic (3.17e-3)" "unprognostic (2.92e-1)" "unprognostic (7.40e-2)" "unprognostic (1.11e-2)" "unprognostic (1.38e-1)" "unprognostic (1.30e-1)" "unprognostic (1.38e-2)" 244.7 53.5 48.7 5.9 63.7 9.3 153.3 31.1 83.6 69.2 13.4 16.1 5.4 22.8 11.9 11.7 32.7 12.6 91.0 60.8 61.9 181.7 271.3 25.4 3.0 71.6 49.8 53.7 30.1 4.2 371.9 1.3 39.4 32.7 6.5 47.7 97.8 55.7 183.1 44.1 12.2 3.4 45.7 18.6 42.2 47.7 40.4 13.1 88.4 103.0 1.2 16.6 26.3 53.6 0.0 0.3 0.3 0.0 70.2 3.8 0.3 0.9 1.4 0.1 0.2 3.0 0.0 0.0 8.0 0.3 0.0 0.2 0.3 0.0 0.1 0.1 0.9 0.3 0.3 8.3 0.5 0.1 0.3 17.1 0.0 0.7 0.0 0.0 0.3 0.2 0.0 0.0 0.2 7.5 13.8 1.3 1.4 1.3 4.5 71.0 0.1 0.1 1.5 0.0 12.9 0.4 1.1 0.9 16.3 2.1 0.1 0.1 4.1 0.1 0.7 0.5 0.2 14.5 0.6 0.2 0.4 0.0 0.5 0.0 0.4 0.0 0.4 3.5 0.0 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.3 0.0 0.8 160.1 0.1 1.0 48.7 63.7 31.1 83.6 60.8 61.9 71.6 49.8 39.4 45.7 40.4 53.6 172.2 28.9 36.8 21.2 11.0 17.2 96.2 46.6 27.3 51.4 106.9 147.2 71.2 20.0 33.5 149.0 4.2 3.3 45.8 42.9 13.7 93.5 2.7 150.9 264.2 31.1 222.4 0.4 15.0 1.3 2.2 191.1 86.6 425.1 8.8 40.3 9.7 21.6 3.6 6.7 5.2 262.7 260.4 3.1 22.2 8.1 109.6 27.3 30.2 1.9 2.2 375.3 0.0 17.1 1.6 9.0 21.8 469.8 56.1 73.3 16.8 13.8 7.2 23.8 565.4 228.1 191.7 1.7 3.0 54.8 13.2 6.7 27.0 73.7 32.9 20.0 RASD2 "MGC:4834, Rhes, TEM2" ENSG00000100302 "RASD family member 2" Q96D21 22 35540831-35553999 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 8 "brain: 212.9" "Group enriched" "Detected in some" 4 "Intestinal goblet cells: 13.1;Sertoli cells: 46.0" "Low cancer specificity" "Detected in many" "Region enriched" "Detected in many" 4 "basal ganglia: 212.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "GAMG: 3.1;hTERT-RPE1: 9.8;SK-BR-3: 5.6;U-2 OS: 3.1;U-87 MG: 4.0" "Region enriched" "Detected in all" 8 "basal ganglia: 589.6" "Region enriched" "Detected in all" 8 "basal ganglia: 429.3" HPA005839 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA005839: AB_1079745" "unprognostic (1.76e-2)" "unprognostic (1.98e-1)" "unprognostic (3.33e-2)" "unprognostic (7.00e-2)" "unprognostic (1.43e-1)" "unprognostic (7.07e-3)" "unprognostic (9.76e-2)" "unprognostic (5.49e-2)" "unprognostic (2.06e-1)" "unprognostic (1.12e-1)" "unprognostic (1.04e-1)" "unprognostic (9.00e-3)" "prognostic unfavorable (2.22e-5)" "unprognostic (3.75e-2)" "unprognostic (1.61e-1)" "unprognostic (8.42e-3)" "unprognostic (6.22e-2)" 1.8 7.3 30.8 2.5 212.9 3.8 2.3 0.0 30.7 3.1 0.0 28.2 2.3 4.7 15.0 1.9 5.6 2.2 8.6 12.5 9.9 1.5 0.4 3.2 0.4 4.6 12.5 1.2 1.6 1.2 2.1 0.2 6.4 15.2 4.0 0.5 4.0 22.7 15.0 1.6 6.2 7.3 1.8 0.2 3.8 0.7 48.4 0.7 1.2 4.5 1.2 4.3 2.5 9.0 0.1 2.2 0.0 0.4 0.0 0.0 0.0 0.5 0.2 0.8 0.6 0.1 0.4 0.0 0.1 1.9 3.1 0.1 0.1 0.0 0.7 0.0 0.5 0.0 0.1 0.0 1.0 0.0 0.0 0.1 2.5 1.6 0.2 9.8 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.2 0.1 0.1 0.2 1.0 0.0 0.7 0.0 0.0 1.5 0.2 1.6 5.6 0.0 0.1 0.4 0.1 0.0 1.3 3.1 0.1 0.7 1.4 0.5 0.0 4.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.8 212.9 0.0 30.7 12.5 9.9 4.6 12.5 6.4 1.8 48.4 9.0 1.2 0.0 0.0 0.0 0.0 0.0 0.2 0.7 0.6 1.7 2.9 3.3 1.9 0.0 0.2 0.0 0.0 0.0 0.7 3.0 0.0 0.2 0.1 0.1 0.2 2.9 0.0 0.0 3.2 0.2 0.0 3.9 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 6.6 13.1 2.0 0.0 0.8 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 1.0 0.7 0.0 2.3 0.7 0.0 0.5 0.1 0.0 0.1 0.2 46.0 0.4 6.9 0.0 0.1 0.0 0.1 0.0 0.2 0.1 0.5 0.3 RASGRP1 "CalDAG-GEFII, RASGRP" ENSG00000172575 "RAS guanyl releasing protein 1" O95267 15 38488103-38565575 "Disease related genes, Predicted intracellular proteins, RAS pathway related proteins" Differentiation "Guanine-nucleotide releasing factor" "Disease variant, Systemic lupus erythematosus" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 23.7;lymphoid tissue: 45.7;retina: 29.7" "Cell type enhanced" "Detected in many" "dendritic cells: 71.4;Excitatory neurons: 54.1;Muller glia cells: 86.9;Plasma cells: 43.0;T-cells: 84.7" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "T-reg: 10.3" "Lineage enriched" "Detected in many" 4 "T-cells: 10.3" "Group enriched" "Detected in many" 4 "HDLM-2: 54.5;JURKAT: 70.2;MOLT-4: 52.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039389 Supported "Plasma membrane,Cytosol" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 24: Non-specific - Transcription regulation" Cytosol "Plasma membrane" "HPA039389: AB_2732481" "unprognostic (3.44e-3)" "unprognostic (1.86e-2)" "unprognostic (1.17e-2)" "unprognostic (3.43e-3)" "unprognostic (1.82e-2)" "unprognostic (3.33e-3)" "unprognostic (9.63e-2)" "unprognostic (4.23e-2)" "unprognostic (1.91e-1)" "unprognostic (1.21e-1)" "unprognostic (4.50e-1)" "unprognostic (3.01e-2)" "unprognostic (2.54e-1)" "unprognostic (2.55e-1)" "unprognostic (1.51e-1)" "unprognostic (3.40e-1)" "unprognostic (9.30e-2)" 1.1 0.8 6.7 10.5 16.8 8.5 1.7 23.7 13.2 0.8 0.0 1.4 2.4 1.4 0.4 5.9 4.4 2.5 1.2 11.6 3.3 5.5 1.1 4.1 21.4 15.3 2.5 0.4 1.8 0.5 0.5 0.9 17.9 0.7 2.1 29.7 1.7 0.7 0.4 6.9 3.6 0.6 0.0 8.9 4.5 2.0 8.8 45.7 0.6 0.7 16.4 3.4 2.0 9.2 0.0 0.4 1.0 0.3 0.0 0.0 0.1 4.1 1.2 2.0 1.7 4.5 0.0 11.6 0.9 0.1 0.2 0.2 2.4 0.0 1.9 54.5 2.2 0.9 0.5 0.0 0.6 0.5 0.8 0.0 0.1 1.1 0.0 0.0 0.0 70.2 0.5 3.6 0.0 1.7 52.3 0.1 0.7 0.0 0.0 14.4 0.3 0.0 2.0 0.1 4.7 1.7 2.6 0.1 0.2 1.5 1.2 0.0 0.2 0.4 1.6 5.6 0.8 8.7 4.6 13.6 0.2 0.1 0.6 0.0 0.0 0.9 5.2 0.0 3.7 1.1 5.7 5.2 0.0 0.6 5.2 5.3 0.2 2.4 0.0 0.0 10.3 1.4 6.7 16.8 23.7 13.2 11.6 3.3 15.3 2.5 17.9 0.0 8.8 9.2 0.9 6.4 10.7 6.5 26.5 2.4 0.4 6.8 4.6 9.6 3.4 2.0 4.5 5.7 2.7 33.1 10.4 0.3 71.4 0.1 3.9 18.4 1.5 7.6 1.6 0.8 0.0 0.0 54.1 10.0 0.2 1.2 1.1 6.6 3.8 0.4 1.1 0.5 0.7 6.7 16.5 1.3 0.0 0.8 6.1 0.7 0.0 3.0 7.2 9.4 3.0 86.9 34.0 2.5 3.9 34.1 0.0 0.0 43.0 0.7 0.3 7.8 0.4 21.3 0.0 1.9 1.3 1.2 3.8 4.0 8.2 0.0 84.7 0.3 0.9 0.5 RASSF3 ENSG00000153179 "Ras association domain family member 3" Q86WH2 12 64507001-64697564 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Langerhans cells: 149.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 6 "neutrophil: 124.1" "Lineage enriched" "Detected in all" 6 "granulocytes: 124.1" "Cell line enhanced" "Detected in all" "SK-MEL-30: 145.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022664, CAB034035, HPA038469" Supported Supported "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 33: SK-MEL-30 - Melanocyte processes" "Cluster 41: Macrophages - Immune response" "Plasma membrane, Cytosol" "CAB022664: , CAB034035: AB_2176848, HPA038469: AB_10671743" "unprognostic (1.63e-1)" "unprognostic (1.33e-1)" "unprognostic (1.35e-1)" "unprognostic (1.47e-1)" "unprognostic (1.55e-1)" "unprognostic (2.37e-2)" "unprognostic (2.55e-3)" "unprognostic (3.73e-1)" "unprognostic (2.37e-1)" "unprognostic (6.21e-2)" "unprognostic (3.66e-2)" "unprognostic (1.49e-1)" "unprognostic (1.45e-3)" "unprognostic (7.16e-2)" "unprognostic (2.01e-1)" "unprognostic (6.98e-2)" "unprognostic (1.59e-2)" 33.1 22.9 13.8 43.3 9.3 17.3 14.9 7.1 9.5 19.4 33.0 106.6 21.1 23.9 15.1 36.8 13.2 29.3 44.3 7.6 9.2 6.9 10.9 32.5 37.0 11.4 20.5 19.6 13.1 3.3 4.6 39.6 13.6 33.0 42.0 1.5 35.6 48.7 45.0 6.8 26.3 60.1 11.4 47.6 34.5 13.5 22.1 15.4 6.5 13.1 33.2 50.3 14.1 13.4 28.1 30.9 9.6 18.6 10.2 14.7 58.3 11.9 61.8 15.8 18.6 22.3 28.9 43.6 24.8 8.6 19.0 12.1 29.6 12.5 19.0 35.5 11.3 28.6 13.0 25.5 27.9 30.5 19.3 10.0 10.7 36.2 26.7 46.1 68.0 20.7 15.4 21.0 18.7 26.5 20.2 19.9 21.4 65.8 18.8 32.5 30.9 18.4 20.8 33.6 21.7 22.7 20.0 3.8 145.5 23.0 17.3 19.0 98.7 12.8 15.6 13.5 13.1 19.5 22.0 28.0 15.4 26.2 37.8 19.6 16.6 12.5 13.2 17.7 11.1 14.1 19.4 14.9 9.1 10.1 19.1 20.3 124.1 12.0 17.7 8.4 22.1 2.8 13.8 9.3 7.1 9.5 7.6 9.2 11.4 20.5 13.6 11.4 22.1 13.4 30.7 3.2 15.4 4.2 32.7 16.3 15.0 5.5 2.8 0.0 12.4 13.7 56.5 30.0 8.9 5.5 0.0 35.5 39.0 67.4 0.0 12.4 0.3 14.4 4.1 31.2 26.4 16.4 8.7 21.2 19.1 14.5 20.9 28.3 6.3 4.7 20.7 4.6 24.1 0.0 16.2 15.8 2.0 69.9 149.3 0.8 2.5 55.7 48.0 49.6 72.7 2.8 32.0 3.5 4.8 24.0 14.5 14.3 9.8 25.5 13.3 1.7 3.9 0.2 13.1 9.2 27.0 0.6 19.3 5.9 11.9 19.7 30.7 1.6 20.7 21.1 RCCD1 MGC14386 ENSG00000166965 "RCC1 domain containing 1" A6NED2 15 90954870-90963125 "Predicted intracellular proteins" "Chromatin regulator" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Erythroid cells: 56.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA039683, HPA040776" Enhanced Enhanced "Plasma membrane,Cytosol" NA Yes "Cluster 35: T-regs - Unknown function" "Cluster 18: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA039683: AB_10794752, HPA040776: AB_10795478" "unprognostic (1.01e-2)" "unprognostic (1.69e-2)" "unprognostic (7.22e-3)" "unprognostic (8.63e-2)" "unprognostic (6.18e-2)" "unprognostic (2.91e-2)" "unprognostic (8.75e-2)" "unprognostic (5.86e-2)" "unprognostic (4.83e-2)" "unprognostic (5.10e-2)" "unprognostic (5.69e-2)" "unprognostic (2.72e-2)" "unprognostic (1.49e-3)" "unprognostic (1.32e-2)" "unprognostic (2.41e-1)" "unprognostic (4.71e-2)" "unprognostic (3.94e-2)" 3.9 8.8 4.1 3.0 4.3 4.6 3.5 5.5 5.2 6.9 5.0 6.3 5.1 5.5 3.5 6.6 6.0 2.0 5.9 4.0 3.6 6.2 6.7 2.6 3.9 3.3 3.2 7.3 9.2 5.2 2.9 2.2 3.7 5.4 4.5 3.1 5.0 2.8 3.8 7.4 4.8 2.8 2.9 4.3 6.7 5.8 3.5 4.7 4.5 1.0 4.7 5.5 5.7 3.4 8.0 11.7 2.7 5.7 6.6 7.8 20.2 9.1 1.6 2.6 2.7 5.6 14.9 28.0 14.2 5.6 0.2 16.8 8.9 2.4 4.3 23.7 18.2 20.3 21.2 8.0 5.5 9.8 7.7 5.8 8.0 2.6 3.6 10.3 4.3 16.2 15.7 18.0 7.8 2.7 11.8 10.2 10.4 9.6 4.8 14.0 13.6 30.4 12.0 3.6 8.8 10.1 15.8 10.0 11.6 14.2 11.5 18.7 6.9 1.6 11.2 6.6 0.4 31.9 14.1 16.9 3.0 21.4 7.7 0.0 0.2 0.0 0.2 0.6 0.5 0.8 0.4 0.7 0.4 0.5 0.8 0.2 0.0 0.5 0.3 0.6 0.6 0.2 4.1 4.3 5.5 5.2 4.0 3.6 3.3 3.2 3.7 2.9 3.5 3.4 6.0 0.0 2.2 7.5 9.7 7.4 11.3 9.0 7.4 6.2 9.9 10.9 8.5 4.3 5.3 7.3 4.2 20.9 5.0 14.9 3.9 8.0 3.1 3.2 8.2 5.0 22.1 56.8 9.6 4.9 18.4 8.0 8.2 5.7 0.0 12.5 4.2 8.5 12.0 0.0 11.3 20.5 6.1 8.1 4.0 6.5 8.7 5.7 5.4 3.7 4.3 11.1 10.3 8.5 2.0 5.0 11.7 7.9 9.4 9.8 17.4 13.7 2.9 2.9 26.3 9.7 9.2 22.2 20.1 17.2 8.9 9.0 4.6 10.2 25.7 7.3 RDX DFNB24 ENSG00000137710 Radixin P35241 11 109864295-110296712 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin capping, Actin-binding" "Deafness, Disease variant, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adrenal gland: 155.0" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 484.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA000263, HPA000763, CAB037312" Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 38000000 "Cluster 2: Granulocytes - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane" Nucleoplasm "CAB037312: AB_261933, HPA000263: AB_1856043, HPA000763: AB_1856042" "unprognostic (2.23e-3)" "unprognostic (2.56e-2)" "unprognostic (3.85e-1)" "unprognostic (2.74e-2)" "unprognostic (6.93e-2)" "unprognostic (9.82e-2)" "unprognostic (2.01e-2)" "unprognostic (1.44e-2)" "unprognostic (3.91e-2)" "unprognostic (6.91e-2)" "unprognostic (1.32e-3)" "unprognostic (6.47e-2)" "unprognostic (4.14e-3)" "unprognostic (5.43e-2)" "unprognostic (4.40e-1)" "unprognostic (1.24e-1)" "unprognostic (1.08e-3)" 40.3 155.0 38.0 17.4 57.7 12.0 16.4 50.0 42.7 32.1 32.8 15.2 6.8 28.8 12.9 27.4 19.7 27.2 41.0 35.1 44.7 50.2 68.5 48.8 11.4 52.7 48.2 52.8 52.7 33.2 7.6 35.3 54.3 25.4 11.1 19.2 20.8 26.0 82.1 11.9 7.4 35.0 45.1 26.6 15.0 33.7 47.7 14.3 45.7 59.7 14.6 27.1 10.1 77.6 69.6 35.3 137.3 54.8 78.8 87.4 79.3 85.8 47.6 54.3 59.2 99.7 115.4 0.1 127.4 104.7 84.9 61.5 77.3 80.4 80.5 41.9 44.2 51.5 107.7 74.1 73.6 19.0 33.2 89.7 45.6 68.0 120.1 89.3 149.8 11.1 73.5 29.5 127.0 120.0 11.0 15.6 44.0 4.0 58.4 31.2 96.8 30.1 68.1 33.5 37.2 40.5 148.5 65.9 52.7 102.5 85.0 29.9 92.6 89.5 66.8 43.9 67.4 9.5 17.3 65.9 34.2 11.3 210.9 29.5 14.8 22.0 11.6 12.5 15.5 11.5 10.2 8.8 12.8 8.3 6.8 5.8 2.0 17.6 9.9 10.3 22.0 8.4 38.0 57.7 50.0 42.7 35.1 44.7 52.7 48.2 54.3 45.1 47.7 77.6 248.8 484.0 98.8 53.5 30.0 56.1 51.8 124.6 56.9 85.9 47.4 45.7 159.3 70.1 77.9 75.4 43.8 122.1 21.6 17.7 109.5 128.1 15.5 109.1 117.2 289.2 22.2 104.8 27.1 423.4 189.8 88.4 19.9 135.3 67.2 132.0 319.2 260.1 85.1 101.0 57.6 7.3 61.1 103.2 59.9 43.6 275.2 71.6 72.9 42.2 135.4 77.0 36.0 68.3 229.4 134.3 22.1 266.7 36.1 65.9 0.1 236.9 52.2 94.8 124.9 74.0 143.8 73.9 257.4 52.8 40.5 227.3 29.2 229.9 11.8 45.9 RELL1 ENSG00000181826 "RELT like 1" Q8IUW5 4 37590800-37686376 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 39.7" "Cell type enhanced" "Detected in many" "Adipocytes: 30.5;Microglial cells: 36.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 59.3" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "RH-30: 45.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA013377 Approved Supported "Plasma membrane,Microtubules" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 65: Plasmacytoid DCs - Unknown function" "Plasma membrane, Microtubules" "HPA013377: AB_1844403" "unprognostic (1.70e-1)" "unprognostic (1.70e-1)" "unprognostic (4.78e-2)" "unprognostic (5.30e-2)" "unprognostic (6.80e-2)" "unprognostic (7.28e-2)" "unprognostic (7.35e-2)" "unprognostic (2.67e-2)" "unprognostic (2.19e-1)" "unprognostic (2.86e-2)" "unprognostic (1.46e-1)" "unprognostic (3.41e-1)" "unprognostic (7.88e-2)" "unprognostic (1.62e-1)" "unprognostic (1.08e-1)" "unprognostic (6.15e-2)" "unprognostic (1.71e-2)" 13.5 2.4 10.6 4.9 15.5 25.6 7.8 20.1 14.9 5.1 9.3 8.3 6.2 5.5 2.7 6.4 5.1 6.1 6.0 8.0 13.3 3.9 4.8 6.6 4.7 29.7 19.3 3.5 2.3 1.5 1.4 6.1 27.7 3.0 6.6 3.1 3.5 3.8 15.8 12.4 5.5 6.0 24.4 7.3 12.3 1.6 20.1 3.7 12.5 4.3 4.8 7.8 4.1 39.7 4.8 5.1 12.9 11.1 10.8 6.2 10.8 8.0 6.9 5.5 7.2 16.8 5.7 1.3 5.7 6.9 9.8 4.3 4.1 7.2 9.6 0.2 2.1 1.8 4.7 18.2 8.1 6.0 4.5 10.6 10.2 7.5 8.2 3.4 24.9 3.3 3.1 5.0 6.4 4.4 7.5 8.3 3.2 6.9 1.5 2.5 45.0 2.2 13.2 5.9 2.9 8.5 6.1 6.6 10.6 3.2 18.0 3.2 29.6 13.8 8.7 10.1 9.5 2.5 2.6 7.3 11.7 12.8 11.4 0.8 15.2 27.4 5.1 5.7 6.3 0.7 6.2 4.9 8.5 0.2 5.3 7.0 59.3 7.7 5.5 9.8 5.5 5.1 10.6 15.5 20.1 14.9 8.0 13.3 29.7 19.3 27.7 24.4 20.1 39.7 30.5 9.6 3.1 16.3 2.9 3.3 2.5 1.7 10.8 0.4 8.1 9.5 2.1 5.7 3.9 0.0 0.0 1.4 9.8 8.4 0.0 3.1 6.5 5.5 9.9 14.4 1.2 3.4 3.3 8.6 3.6 10.7 22.4 2.4 2.5 0.5 6.4 0.9 2.6 3.3 2.4 1.6 0.0 3.2 2.7 8.1 3.7 9.2 1.8 36.5 4.1 4.0 0.0 22.6 12.5 10.3 2.9 6.0 15.5 2.7 6.7 0.2 3.3 1.4 13.1 18.8 16.4 0.8 0.3 5.5 4.7 5.2 10.6 5.1 1.1 3.8 RFPL1 RNF78 ENSG00000128250 "Ret finger protein like 1" O75677 22 29438583-29442455 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 10.3;retina: 3.0" "Group enriched" "Detected in some" 7 "Early spermatids: 9.1;Hepatic stellate cells: 8.6" "Not detected" "Not detected" "Region enhanced" "Detected in many" "cerebral cortex: 10.3" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 7.5;HMC-1: 2.7;Karpas-707: 3.0;SH-SY5Y: 3.7;SiHa: 1.8;THP-1: 3.5" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 58: Brain - Synaptic function" "Cluster 44: HDLM-2 - Immune response" "Cluster 29: Early spermatids - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (4.54e-1)" "unprognostic (6.63e-8)" "unprognostic (3.14e-3)" "unprognostic (1.89e-1)" 0.1 2.9 2.5 0.2 2.3 0.0 0.0 0.0 10.3 0.1 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.2 0.0 4.1 0.0 0.0 1.1 0.0 0.2 0.0 0.0 2.5 0.1 0.2 0.3 0.1 0.0 1.3 0.0 3.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 1.6 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 7.5 0.5 0.0 0.6 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 3.0 0.0 0.1 0.1 0.0 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.7 1.8 0.0 0.0 0.1 0.0 3.5 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.1 0.1 0.1 0.5 0.0 0.1 0.0 0.0 0.3 0.0 0.2 0.1 2.5 2.3 0.0 10.3 4.1 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 9.1 0.0 0.1 0.0 0.0 0.0 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.6 0.4 0.0 0.0 0.8 0.0 0.0 1.2 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 RFPL2 RNF79 ENSG00000128253 "Ret finger protein like 2" O75678 22 32190435-32205001 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in some" 8 "brain: 10.2;prostate: 3.8" "Group enriched" "Detected in some" 4 "Excitatory neurons: 17.6;Inhibitory neurons: 8.6" "Cancer enriched" "Detected in single" 15 "prostate cancer: 5.6" "Region enriched" "Detected in many" 4 "cerebral cortex: 10.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "HPA046608, HPA048320, HPA072380" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 10: Brain - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nuclear speckles" "Plasma membrane" "HPA046608: , HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (3.81e-2)" "unprognostic (4.05e-2)" "unprognostic (8.29e-2)" "unprognostic (9.66e-3)" "unprognostic (2.54e-1)" "unprognostic (9.90e-2)" "unprognostic (2.59e-1)" "unprognostic (6.02e-3)" "unprognostic (2.22e-2)" "unprognostic (3.44e-2)" "unprognostic (8.64e-3)" "prognostic favorable (4.16e-4)" "unprognostic (2.04e-4)" "unprognostic (6.02e-2)" "unprognostic (3.28e-2)" "unprognostic (5.62e-7)" "unprognostic (3.50e-2)" 0.0 0.5 1.5 0.0 1.9 0.4 0.0 0.0 10.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.3 0.9 0.0 0.1 0.0 0.1 1.7 0.7 0.3 0.0 0.0 0.1 0.0 1.7 3.8 0.0 0.9 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.7 0.2 0.0 0.1 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.3 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.9 0.0 10.2 2.3 0.9 1.7 0.7 1.7 0.0 1.0 1.6 0.1 0.0 0.0 1.3 0.0 0.0 0.1 0.0 0.0 0.7 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.1 0.0 2.7 17.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 8.6 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.5 1.2 0.0 0.0 0.0 0.0 3.1 0.0 0.3 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.1 RFPL3 RNF120 ENSG00000128276 "Ret finger protein like 3" O75679 22 32354885-32361161 "Predicted intracellular proteins" "Host-virus interaction" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "testis: 24.8" "Cell type enhanced" "Detected in some" "Early spermatids: 2.6;Spermatocytes: 2.0;Spermatogonia: 1.4" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.6;NB-4: 2.2;U-266/70: 2.5;U-266/84: 2.6" "HPA048320, HPA072380" Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 24: NB-4 - Immune response" "Cluster 66: Spermatocytes - Spermatogenesis" "Nuclear speckles" "Plasma membrane" "HPA048320: AB_2680356, HPA072380: AB_2686515" "unprognostic (1.63e-1)" "unprognostic (9.90e-2)" "unprognostic (1.10e-1)" "unprognostic (1.05e-1)" "unprognostic (1.52e-2)" "unprognostic (1.97e-1)" "unprognostic (3.25e-2)" "unprognostic (4.31e-2)" "unprognostic (1.90e-1)" "unprognostic (6.32e-2)" 0.1 0.1 0.0 0.2 0.1 1.4 0.0 0.5 0.2 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.1 0.2 0.0 0.0 0.1 0.1 0.6 0.1 0.1 0.5 0.7 0.0 0.1 0.1 0.1 0.3 0.0 2.4 0.5 0.0 0.5 1.3 0.3 0.0 0.0 0.7 0.1 24.8 0.2 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.4 1.0 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.1 1.0 0.5 0.0 0.0 0.0 0.7 0.2 0.0 0.0 0.0 0.0 0.6 0.0 0.8 0.0 0.8 0.0 0.4 0.6 2.2 0.1 0.1 0.0 1.1 0.2 0.3 0.0 0.2 0.8 0.1 0.0 0.2 0.6 0.2 0.0 0.2 0.0 0.0 0.4 0.1 0.0 2.5 2.6 0.0 0.0 0.7 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.2 0.2 0.0 0.1 0.1 0.1 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 1.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RGP1 KIAA0258 ENSG00000107185 "RGP1 homolog, RAB6A GEF complex partner 1" Q92546 9 35749287-35758585 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020414, HPA021085" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 20: HeLa - Mitochondria" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA020414: AB_1852289, HPA021085: AB_1852291" "unprognostic (2.10e-1)" "unprognostic (3.22e-2)" "unprognostic (1.03e-1)" "unprognostic (2.01e-2)" "unprognostic (3.35e-2)" "unprognostic (1.47e-1)" "prognostic unfavorable (7.09e-4)" "unprognostic (2.22e-1)" "unprognostic (5.42e-2)" "unprognostic (1.51e-3)" "unprognostic (1.81e-3)" "unprognostic (9.77e-2)" "prognostic favorable (8.55e-13)" "unprognostic (2.46e-2)" "unprognostic (1.68e-1)" "unprognostic (3.03e-3)" "unprognostic (1.18e-1)" 9.8 10.4 7.5 8.7 6.9 5.6 8.5 6.6 6.7 7.9 3.4 12.9 10.7 8.8 7.8 8.6 8.3 6.0 12.9 7.3 7.8 11.5 7.4 9.1 7.5 5.8 6.3 10.1 10.7 19.1 10.5 9.3 6.0 8.7 13.4 7.8 11.0 11.4 17.3 9.4 11.6 9.8 5.6 7.4 10.3 6.4 8.0 8.9 12.2 18.6 9.6 8.0 6.5 5.9 18.0 16.6 18.9 15.8 17.3 18.6 11.1 13.9 20.1 18.9 17.4 14.2 6.7 13.9 9.7 17.8 34.9 9.9 18.3 26.2 15.5 18.6 10.7 11.9 32.9 10.7 16.3 13.0 16.1 18.8 32.8 19.9 24.0 27.0 22.7 10.6 8.2 7.5 17.3 8.5 4.0 4.7 7.9 14.7 19.2 13.2 13.5 9.9 16.5 12.4 13.8 14.9 12.3 17.0 11.2 16.6 14.2 6.2 29.0 15.1 18.9 10.5 11.8 11.1 16.5 14.3 21.5 5.4 19.7 1.1 0.2 0.4 0.7 0.4 1.1 0.8 0.5 0.8 0.1 1.0 0.6 0.7 0.7 1.1 0.6 0.6 0.5 0.2 7.5 6.9 6.6 6.7 7.3 7.8 5.8 6.3 6.0 5.6 8.0 5.9 13.9 6.4 12.6 0.0 23.4 5.7 24.5 14.8 9.1 40.8 15.0 10.0 16.6 18.6 15.8 27.6 20.9 10.9 19.1 46.1 13.7 20.1 17.5 9.8 8.3 14.9 43.3 8.6 0.2 17.6 10.6 7.5 18.8 14.9 5.7 33.4 16.1 16.4 7.5 16.8 0.1 26.0 22.4 7.7 6.1 36.8 8.4 5.7 1.8 0.0 11.1 18.8 25.7 0.0 0.1 20.6 38.3 10.9 15.2 25.3 36.3 14.2 17.7 22.3 6.6 11.8 9.3 16.6 6.1 8.1 5.3 10.3 16.4 7.1 28.9 28.8 RGS10 ENSG00000148908 "Regulator of G protein signaling 10" O43665 10 119499817-119542719 "Predicted intracellular proteins" "GTPase activation, Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 222.9" "Cell type enhanced" "Detected in many" "granulocytes: 291.2;Hofbauer cells: 528.1;Kupffer cells: 297.2;Langerhans cells: 358.3;Macrophages: 529.3;monocytes: 294.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HMC-1: 474.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004559, HPA021305, HPA058485" Enhanced Supported Supported "Nucleoplasm,Plasma membrane" NA NA 840000 "Cluster 32: T-cells - Unknown function" "Cluster 3: T-cells - Adaptive immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 51: Myeloid cells - Hemostasis" "Nucleoplasm, Plasma membrane" "CAB004559: AB_628216, HPA021305: AB_1856225, HPA058485: AB_2683732" "unprognostic (1.64e-2)" "prognostic favorable (6.81e-4)" "unprognostic (7.98e-2)" "prognostic favorable (6.32e-4)" "unprognostic (5.21e-2)" "unprognostic (6.19e-2)" "unprognostic (4.32e-3)" "unprognostic (6.35e-2)" "unprognostic (9.90e-3)" "unprognostic (1.10e-1)" "unprognostic (1.42e-2)" "unprognostic (1.30e-1)" "prognostic unfavorable (4.20e-10)" "unprognostic (2.50e-1)" "unprognostic (9.20e-2)" "unprognostic (7.70e-2)" "unprognostic (7.92e-3)" 25.1 20.6 20.0 59.3 20.2 74.5 40.7 22.3 30.4 63.9 22.3 114.3 34.2 38.5 15.8 51.5 28.5 38.3 13.4 20.7 24.5 18.8 11.4 28.1 119.0 28.6 24.5 22.5 7.0 6.9 13.8 45.6 28.9 43.2 49.7 2.6 41.0 20.3 31.5 22.9 58.3 42.8 26.1 48.7 30.0 4.9 26.1 222.9 33.0 11.6 96.5 50.3 45.8 37.2 165.2 31.2 2.4 294.7 41.4 262.6 25.9 74.9 118.1 45.3 73.5 9.8 38.7 66.8 38.1 60.9 45.7 35.4 44.3 48.2 123.8 32.0 42.8 183.1 8.9 24.2 63.1 40.0 474.0 100.7 63.1 88.3 84.4 159.4 88.2 65.4 47.6 58.5 55.0 79.2 221.9 134.8 13.5 21.2 71.1 43.8 0.3 26.1 24.7 40.4 10.8 9.3 14.4 192.6 285.3 36.3 35.1 71.7 108.3 25.4 21.9 36.1 67.8 2.7 46.0 27.0 7.6 166.5 11.4 184.8 116.0 1.4 77.9 151.4 82.9 36.0 169.6 134.9 224.3 21.7 397.5 303.3 52.5 44.3 130.4 133.2 202.3 372.5 20.0 20.2 22.3 30.4 20.7 24.5 28.6 24.5 28.9 26.1 26.1 37.2 10.4 0.0 13.1 2.6 60.3 36.8 25.7 104.5 27.9 0.2 68.9 96.6 1.1 1.5 39.7 1.8 0.0 14.0 70.1 7.1 60.7 0.8 2.1 89.8 25.1 12.7 18.7 156.6 0.2 6.4 34.8 68.6 11.2 53.6 291.2 101.2 13.2 1.5 528.1 0.0 1.8 85.7 32.6 297.2 358.3 5.1 50.1 529.3 94.3 67.5 294.5 1.8 50.4 0.5 0.2 9.9 10.0 9.4 32.1 88.8 3.3 5.2 24.6 0.8 13.1 14.4 31.8 0.3 9.3 39.6 28.1 10.1 164.7 3.5 19.3 41.4 RHCE "CD240CE, RH" ENSG00000188672 "Rh blood group CcEe antigens" P18577 1 25362249-25430192 "Blood group antigen proteins, CD markers, Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 9 "bone marrow: 48.5" "Cell type enriched" "Detected in some" 67 "Erythroid cells: 511.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 5 "HEL: 81.3" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (1.37e-1)" "unprognostic (3.53e-1)" "unprognostic (2.38e-1)" "unprognostic (6.75e-2)" "unprognostic (1.41e-2)" "unprognostic (4.91e-2)" "unprognostic (7.01e-2)" "unprognostic (3.12e-2)" "unprognostic (3.81e-2)" "unprognostic (1.35e-1)" "unprognostic (6.08e-2)" "unprognostic (4.61e-2)" "unprognostic (5.77e-5)" "unprognostic (1.38e-1)" "unprognostic (3.94e-2)" "unprognostic (7.15e-3)" "unprognostic (1.63e-1)" 0.3 0.6 1.5 0.1 1.9 48.5 0.3 1.6 3.3 0.3 1.2 0.2 0.2 0.2 4.2 0.6 1.0 0.3 1.2 1.5 1.4 0.4 1.7 0.4 0.5 1.9 1.6 0.5 1.2 0.1 3.4 1.1 1.9 1.0 0.3 2.2 5.5 0.2 1.5 0.6 0.1 0.0 1.5 1.1 0.4 2.2 1.6 0.8 0.6 0.9 0.3 0.1 0.5 2.2 0.2 0.1 0.2 0.5 0.9 0.6 0.1 0.3 0.3 0.4 0.1 0.1 1.5 0.7 1.1 1.0 0.1 0.3 0.0 0.2 0.2 0.4 0.1 81.3 0.0 0.0 1.1 0.0 0.6 1.9 1.5 0.6 0.5 0.0 0.0 0.6 17.5 0.4 0.5 0.8 0.0 0.6 1.7 0.7 0.5 0.2 0.2 2.6 0.0 0.0 0.7 0.8 0.3 0.3 1.0 0.8 0.5 0.0 0.1 0.2 0.0 0.9 0.0 5.1 1.4 1.0 2.9 0.9 0.5 0.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 1.5 1.9 1.6 3.3 1.5 1.4 1.9 1.6 1.9 1.5 1.6 2.2 0.8 0.0 0.0 5.5 0.8 0.5 0.5 0.3 0.6 4.2 1.1 2.5 0.7 1.5 0.2 0.0 0.0 0.8 1.2 0.5 0.0 0.3 1.1 1.2 0.7 0.4 0.0 511.8 2.9 0.2 0.7 0.4 3.6 0.8 4.5 0.6 0.0 0.7 0.2 6.7 2.3 0.0 0.0 0.6 0.4 0.5 0.6 1.7 0.0 0.0 0.0 4.7 1.0 2.0 2.7 0.5 0.0 0.7 3.0 0.3 0.1 0.0 0.9 2.4 6.6 0.5 0.5 3.0 7.6 0.6 1.4 0.8 0.8 0.7 0.3 0.7 RHD "CD240D, DIIIc, RH, Rh30a, Rh4, RhII, RhPI" ENSG00000187010 "Rh blood group D antigen" Q02161 1 25272393-25330445 "Blood group antigen proteins, CD markers, Predicted membrane proteins, Transporters" "Blood group antigen" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "bone marrow: 15.8" "Cell type enriched" "Detected in some" 21 "Erythroid cells: 153.0" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in many" "neutrophil: 6.3" "Lineage enriched" "Detected in many" 5 "granulocytes: 6.3" "Group enriched" "Detected in some" 7 "HEL: 43.0;K-562: 13.0" "HPA060951, HPA077385" Supported Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 6: Erythroid cells - Oxygen transport" "Nucleoplasm, Plasma membrane" "HPA060951: , HPA077385: " "unprognostic (4.75e-3)" "unprognostic (7.70e-2)" "unprognostic (1.34e-1)" "unprognostic (1.38e-1)" "unprognostic (1.09e-2)" "unprognostic (4.84e-2)" "unprognostic (1.11e-2)" "unprognostic (5.25e-2)" "unprognostic (1.11e-2)" "unprognostic (1.91e-1)" "unprognostic (1.27e-2)" "unprognostic (1.89e-1)" "unprognostic (4.96e-3)" "unprognostic (1.93e-1)" "unprognostic (8.09e-2)" "unprognostic (5.53e-2)" "unprognostic (4.92e-3)" 0.1 0.4 0.4 0.5 1.0 15.8 0.1 1.4 0.7 0.3 0.1 0.1 0.3 0.4 0.1 0.3 0.2 0.4 0.3 0.4 0.1 0.1 0.1 0.2 0.7 0.3 0.1 0.5 0.4 0.0 0.2 0.3 0.2 0.3 0.1 1.9 2.4 0.0 3.8 2.0 0.3 0.0 0.0 0.6 0.2 0.5 0.5 0.1 0.3 0.0 0.1 0.1 0.1 1.2 0.2 0.0 0.3 0.3 0.1 0.0 0.5 0.0 0.1 0.1 0.0 0.1 0.3 0.6 0.1 0.0 0.1 0.2 0.0 0.0 0.0 0.7 0.2 43.0 1.0 0.2 0.0 0.3 0.4 0.0 0.1 0.1 0.1 0.2 0.1 0.2 13.0 0.9 0.1 0.2 0.2 0.3 4.0 0.0 0.2 0.3 0.2 0.1 0.0 0.1 0.6 0.4 0.1 0.2 0.1 0.1 0.2 0.6 0.4 0.7 0.2 0.5 0.2 0.4 0.2 0.2 0.6 0.2 0.2 4.3 0.9 2.0 0.6 0.4 0.7 1.0 0.8 0.5 0.1 1.3 0.9 0.8 6.3 1.0 0.6 0.4 0.7 0.6 0.4 1.0 1.4 0.7 0.4 0.1 0.3 0.1 0.2 0.0 0.5 1.2 0.2 0.0 0.5 1.0 0.6 0.1 0.2 0.0 0.0 0.3 0.1 0.1 1.0 0.0 0.6 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.2 0.1 0.3 1.0 0.0 153.0 5.2 0.2 0.0 0.2 0.0 0.3 0.0 0.2 0.4 0.0 0.1 0.0 4.3 0.0 0.0 0.3 0.3 0.0 0.0 3.0 0.0 3.7 0.0 0.4 0.0 7.1 6.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.4 0.0 1.2 0.4 0.1 0.6 0.0 0.0 0.0 0.7 0.2 0.0 0.1 RHOA "ARH12, ARHA, Rho12, RHOH12" ENSG00000067560 "Ras homolog family member A" P61586 3 49359139-49412998 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, RAS pathway related proteins" "Cell cycle, Cell division, Host-virus interaction" Hydrolase "Cancer-related genes, Disease variant, Ectodermal dysplasia, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB005052 Approved Supported "Plasma membrane,Cytosol" NA NA 1500000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 52: Non-specific - Ribosome" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "CAB005052: AB_562216" "unprognostic (1.50e-1)" "unprognostic (3.38e-1)" "prognostic favorable (3.08e-4)" "unprognostic (8.75e-2)" "unprognostic (1.63e-1)" "unprognostic (1.24e-1)" "prognostic unfavorable (9.15e-4)" "unprognostic (1.39e-1)" "unprognostic (8.83e-2)" "unprognostic (9.44e-3)" "unprognostic (2.21e-2)" "unprognostic (4.29e-2)" "prognostic favorable (3.21e-6)" "unprognostic (5.14e-2)" "unprognostic (7.50e-2)" "unprognostic (1.57e-1)" "unprognostic (4.52e-2)" 452.4 315.0 234.6 357.9 258.6 473.4 360.0 257.1 274.1 310.4 237.4 351.9 274.6 293.8 298.6 362.6 269.2 267.1 269.6 220.8 271.2 286.9 274.5 430.9 396.3 282.9 245.8 297.2 225.3 269.4 164.3 396.8 287.2 244.5 369.3 113.3 238.0 315.6 331.0 281.3 281.0 416.9 259.3 329.1 292.1 154.1 257.5 387.7 326.3 298.5 454.9 358.2 273.6 292.5 470.4 406.1 500.9 512.7 569.9 858.9 370.8 930.1 735.7 790.3 722.4 347.6 527.4 721.8 251.6 1404.1 448.8 259.5 560.4 630.6 817.6 505.7 323.3 678.8 488.0 416.0 604.2 647.9 472.8 668.2 437.8 643.2 508.1 799.7 1038.0 391.9 361.1 437.9 967.5 254.3 717.3 739.0 441.4 548.2 497.1 325.5 451.4 610.5 701.9 559.6 167.7 387.3 599.0 464.5 495.4 499.4 301.7 819.6 972.1 558.4 483.2 737.2 725.7 388.0 775.6 754.8 567.9 691.6 678.3 716.9 1105.5 1160.5 480.1 1358.8 423.8 432.7 415.6 479.6 806.9 379.3 314.5 397.1 1282.7 440.9 1398.1 645.5 554.9 1884.8 234.6 258.6 257.1 274.1 220.8 271.2 282.9 245.8 287.2 259.3 257.5 292.5 502.8 387.8 265.2 20.5 374.6 270.9 260.0 236.1 251.6 47.1 239.4 223.1 141.1 178.7 220.9 180.3 6.2 355.8 373.1 447.2 340.4 339.5 48.2 174.2 243.7 413.8 234.4 319.3 26.1 347.8 709.8 386.2 313.9 201.0 257.3 141.6 312.7 173.2 760.0 82.4 27.0 344.9 191.2 771.9 495.8 55.6 335.2 683.7 327.3 52.5 710.0 219.9 389.3 24.6 51.4 398.0 354.6 407.7 375.7 334.1 341.3 350.8 201.1 40.8 276.1 354.1 450.1 264.4 253.6 390.8 279.6 525.2 359.5 299.1 347.7 371.4 RHOXF2 "CT107, PEPP-2, PEPP2, THG1" ENSG00000131721 "Rhox homeobox family member 2" Q9BQY4 X 120158613-120165630 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "testis: 11.0" "Group enriched" "Detected in some" 22 "Spermatocytes: 6.6;Spermatogonia: 7.1" "Cancer enhanced" "Detected in single" "testis cancer: 0.8" "Low region specificity" "Detected in single" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "K-562: 100.5;NB-4: 69.9;THP-1: 27.9;U-266/84: 47.2" "HPA003314, CAB020794" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "CAB020794: , HPA003314: AB_1855193" "unprognostic (1.60e-1)" "unprognostic (5.04e-2)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 2.1 0.5 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.9 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.0 11.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 12.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 100.5 0.0 0.0 0.0 0.0 69.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 27.9 0.5 0.0 0.0 0.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.1 2.1 0.5 0.1 0.7 0.9 0.7 0.3 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.6 7.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RHOXF2B ENSG00000203989 "Rhox homeobox family member 2B" P0C7M4 X 120072264-120077690 "Predicted intracellular proteins, Transcription factors" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 85 "testis: 21.2" "Cell type enriched" "Detected in single" 6 "Spermatogonia: 1.8" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "HL-60: 596.6;K-562: 903.3;NB-4: 1129.0" HPA003314 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 1: K-562 - Erythropoiesis" "Cluster 20: Spermatogonia & Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA003314: AB_1855193" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.2 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 596.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 903.3 0.0 0.0 0.0 0.0 1129.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 94.3 3.0 0.0 0.0 0.6 0.2 0.0 156.5 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIC8A "synembryn, synembryn-A" ENSG00000177963 "RIC8 guanine nucleotide exchange factor A" Q9NPQ8 11 207511-215113 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041491, CAB046012" Approved Approved "Plasma membrane,Cytosol" NA NA 10000 "Cluster 44: Non-specific - Transcription" "Cluster 57: Non-specific - Angiogenesis" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "CAB046012: AB_11129402, HPA041491: AB_2677510" "unprognostic (3.93e-2)" "unprognostic (8.69e-2)" "unprognostic (1.62e-1)" "prognostic favorable (8.60e-4)" "unprognostic (1.61e-2)" "unprognostic (2.21e-1)" "prognostic unfavorable (1.11e-6)" "unprognostic (2.13e-3)" "unprognostic (8.70e-2)" "unprognostic (7.68e-2)" "unprognostic (1.56e-1)" "unprognostic (8.35e-2)" "unprognostic (2.63e-3)" "unprognostic (5.35e-2)" "unprognostic (2.57e-1)" "unprognostic (2.14e-1)" "unprognostic (1.60e-1)" 39.2 39.6 43.0 34.8 43.6 40.6 37.4 42.1 48.5 41.2 46.6 46.3 29.5 44.2 41.8 43.1 41.1 30.6 42.9 45.4 43.7 36.5 37.8 37.6 37.6 43.5 44.4 39.7 39.3 34.2 38.1 34.1 44.2 39.0 30.8 24.8 34.4 40.3 32.8 39.5 38.1 49.4 43.4 41.6 38.1 44.0 44.0 41.6 33.7 28.3 41.8 45.9 36.6 45.0 176.3 83.9 66.8 66.7 89.7 73.4 46.3 124.1 99.2 166.0 114.2 72.6 121.1 69.6 50.5 189.0 125.7 93.4 76.4 131.4 92.0 84.5 76.7 39.4 59.5 67.8 72.3 66.5 125.8 80.6 114.3 103.2 92.6 85.2 82.8 72.8 68.7 66.0 129.3 71.1 79.6 52.6 61.1 74.0 103.0 74.0 66.0 47.5 96.9 45.6 69.2 62.2 96.3 107.1 67.1 63.9 76.1 52.8 93.4 109.2 96.5 40.4 117.3 72.6 117.6 67.8 107.7 59.5 83.5 72.9 41.1 88.3 79.0 49.7 78.2 64.4 70.1 69.0 43.7 55.1 59.9 60.6 59.9 73.0 61.0 35.8 65.0 86.6 43.0 43.6 42.1 48.5 45.4 43.7 43.5 44.4 44.2 43.4 44.0 45.0 30.9 16.0 21.1 10.7 28.7 17.7 20.5 38.6 17.1 28.1 22.5 27.2 23.5 28.6 25.5 25.8 10.4 41.4 46.5 26.3 27.4 53.1 20.2 15.9 24.3 27.2 20.3 27.4 9.4 44.2 60.0 30.4 23.0 19.7 17.7 28.8 27.8 17.1 46.8 32.0 8.4 19.2 30.5 27.4 11.5 17.3 30.7 27.5 28.4 11.2 38.9 43.4 30.9 5.0 7.8 71.6 25.5 39.9 35.2 26.5 29.9 23.0 20.8 33.1 19.7 20.7 35.4 93.2 62.5 20.9 19.5 32.4 34.8 30.2 25.0 17.0 RIC8B "FLJ10620, hSyn, RIC8" ENSG00000111785 "RIC8 guanine nucleotide exchange factor B" Q9NVN3 12 106774621-106889316 "Predicted intracellular proteins" "Guanine-nucleotide releasing factor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 96.4;Inhibitory neurons: 93.9;Microglial cells: 58.1;Oligodendrocyte precursor cells: 76.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039970, HPA042746" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 39: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Cytosol "Plasma membrane" "HPA039970: , HPA042746: AB_2678143" "unprognostic (1.18e-1)" "unprognostic (1.61e-1)" "unprognostic (9.87e-3)" "unprognostic (5.43e-2)" "unprognostic (3.28e-2)" "unprognostic (8.09e-2)" "unprognostic (5.74e-2)" "unprognostic (2.60e-1)" "unprognostic (1.99e-2)" "unprognostic (3.83e-1)" "unprognostic (1.10e-3)" "unprognostic (5.13e-2)" "unprognostic (3.65e-3)" "unprognostic (2.21e-1)" "unprognostic (3.18e-2)" "unprognostic (1.34e-1)" "unprognostic (1.01e-2)" 5.5 5.3 7.7 3.2 26.1 1.3 4.9 7.9 9.7 5.5 6.6 6.4 3.1 7.0 4.3 3.1 6.3 5.6 8.7 6.8 8.7 7.2 5.8 3.7 2.5 6.6 11.5 5.8 6.2 11.5 7.8 3.7 6.5 4.5 3.9 12.6 3.5 8.2 7.3 2.7 4.1 6.4 5.4 4.7 4.1 4.4 9.3 6.5 9.3 8.2 2.4 5.9 4.3 8.4 3.6 11.0 20.7 8.3 9.7 11.7 2.5 11.7 9.3 10.3 9.6 3.7 3.1 2.2 8.0 6.7 4.1 6.2 7.5 4.1 12.3 25.0 10.0 7.5 5.2 4.7 7.5 7.2 4.9 6.8 5.2 6.7 3.4 12.2 9.6 7.7 4.7 0.1 9.4 2.9 8.2 7.8 10.4 5.6 11.0 7.1 12.0 7.2 8.7 3.2 15.1 9.7 8.5 5.3 5.9 7.8 4.7 4.9 9.3 8.3 4.6 5.6 8.5 6.1 13.7 0.1 4.0 4.9 12.4 0.9 1.4 1.2 1.9 0.8 2.2 0.4 1.0 0.9 1.3 0.2 0.8 0.8 0.6 0.9 0.7 0.8 1.1 1.0 7.7 26.1 7.9 9.7 6.8 8.7 6.6 11.5 6.5 5.4 9.3 8.4 10.0 6.4 7.8 47.7 5.9 3.3 3.9 5.5 5.2 14.4 8.5 7.4 33.9 25.8 5.8 3.7 10.4 7.1 5.0 10.9 7.9 21.7 5.7 12.7 17.5 11.2 18.6 5.5 96.4 4.0 3.7 10.5 7.7 7.3 8.2 10.4 15.0 9.2 3.6 6.7 93.9 7.8 8.2 6.6 3.9 5.0 12.8 4.6 7.2 58.1 3.8 5.5 14.4 76.9 52.9 6.6 4.8 19.2 2.6 1.7 7.2 6.7 10.8 45.0 13.1 18.6 9.3 18.4 8.8 2.6 2.8 1.4 7.6 10.6 6.7 1.5 RIMBP3 "KIAA1666, RIMBP3.1, RIMBP3A" ENSG00000275793 "RIMS binding protein 3" Q9UFD9 22 18605815-18611919 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 27 "brain: 35.7;choroid plexus: 24.5;testis: 28.4" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "MOLT-4: 3.0;THP-1: 3.2" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 30: Non-specific - Translation" "Cluster 70: Brain - Nervous system development" "Cluster 43: THP-1 - Innate immune response" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.55e-2)" "unprognostic (3.95e-3)" "unprognostic (1.62e-1)" "unprognostic (3.95e-2)" "unprognostic (2.29e-2)" "unprognostic (9.81e-3)" "unprognostic (1.83e-3)" "unprognostic (1.84e-1)" "unprognostic (2.71e-1)" "unprognostic (4.72e-3)" "unprognostic (6.06e-3)" "unprognostic (9.58e-2)" "unprognostic (8.49e-3)" "unprognostic (7.23e-2)" "unprognostic (1.03e-1)" "unprognostic (2.69e-3)" "unprognostic (7.95e-2)" 0.1 0.2 7.9 0.4 10.8 0.1 0.0 35.7 22.0 0.1 24.5 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.0 11.0 11.7 0.0 0.0 0.2 0.8 14.9 10.1 0.1 0.1 0.3 0.1 0.2 26.2 0.2 0.1 0.1 0.2 0.1 0.0 0.1 0.2 0.0 19.6 0.7 0.2 28.4 13.5 1.0 0.4 0.0 0.5 0.0 0.0 32.4 0.4 1.3 0.5 0.4 0.7 0.3 0.0 0.5 1.4 0.6 0.7 0.0 0.0 0.3 0.6 0.2 0.4 0.3 0.3 0.0 0.1 1.4 0.4 0.6 0.3 0.5 0.0 2.0 0.0 0.1 0.0 0.3 0.0 0.1 0.0 1.1 0.2 0.3 0.5 0.6 3.0 1.7 0.6 0.6 0.1 1.2 1.6 0.2 0.1 0.1 0.8 0.1 1.2 0.0 0.2 0.1 0.1 3.2 0.1 1.0 0.7 0.5 0.3 0.0 0.4 0.3 0.5 0.7 1.1 0.0 0.2 0.2 0.1 0.1 0.4 0.1 0.2 0.2 0.2 0.1 0.3 0.2 0.1 0.3 0.0 0.0 0.2 0.3 7.9 10.8 35.7 22.0 11.0 11.7 14.9 10.1 26.2 19.6 13.5 32.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3B ENSG00000274600 "RIMS binding protein 3B" A6NNM3 22 21383374-21389478 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "No human protein/transcript evidence" "Evidence at protein level" "Group enriched" "Detected in some" 49 "brain: 41.3;choroid plexus: 18.4;testis: 13.6" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "NB-4: 1.2;RH-30: 1.1;THP-1: 2.1" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 43: THP-1 - Innate immune response" "Cluster 58: T-cells - T-cell receptor" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (3.78e-1)" "unprognostic (3.54e-2)" "unprognostic (1.53e-2)" "unprognostic (1.51e-1)" "unprognostic (3.28e-1)" "unprognostic (5.35e-2)" "unprognostic (4.37e-1)" "unprognostic (3.61e-4)" "unprognostic (1.69e-2)" "unprognostic (7.11e-2)" 0.0 0.1 8.2 0.4 12.8 0.0 0.0 41.3 19.1 0.0 18.4 0.0 0.1 0.0 0.1 0.0 0.1 0.0 0.0 10.4 13.6 0.0 0.0 0.1 0.3 16.5 12.6 0.0 0.1 0.2 0.0 0.2 19.2 0.1 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 16.2 0.2 0.0 13.6 13.2 0.4 0.1 0.0 0.2 0.0 0.0 29.6 0.0 0.5 0.1 0.1 0.3 0.2 0.1 0.1 0.4 0.2 0.2 0.0 0.1 0.1 0.6 0.0 0.1 0.0 0.2 0.0 0.0 0.7 0.3 0.2 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.2 0.1 0.2 0.2 0.9 1.2 0.1 0.2 0.1 0.8 1.1 0.0 0.0 0.0 0.2 0.0 0.5 0.0 0.2 0.0 0.0 2.1 0.0 0.1 0.1 0.2 0.1 0.1 0.1 0.0 0.3 0.2 0.6 0.0 0.1 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 0.0 0.2 0.1 8.2 12.8 41.3 19.1 10.4 13.6 16.5 12.6 19.2 16.2 13.2 29.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 RIMBP3C ENSG00000183246 "RIMS binding protein 3C" A6NJZ7 22 21545678-21551461 "Predicted intracellular proteins" "Differentiation, Spermatogenesis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 21 "testis: 6.1" "Cell type enhanced" "Detected in some" "Early spermatids: 30.7;Late spermatids: 49.4;Spermatocytes: 11.7" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" HPA001183 Supported Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 83: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Vesicles, Plasma membrane" "HPA001183: AB_1079205" "unprognostic (1.74e-1)" "unprognostic (4.05e-2)" "unprognostic (3.49e-2)" "unprognostic (2.18e-1)" "unprognostic (8.30e-2)" "unprognostic (4.53e-2)" "unprognostic (6.65e-2)" "unprognostic (1.15e-3)" "unprognostic (6.23e-2)" "unprognostic (2.17e-6)" "unprognostic (3.04e-1)" "unprognostic (3.29e-1)" "unprognostic (3.76e-6)" "unprognostic (1.66e-2)" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 6.1 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 30.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 49.4 0.6 0.1 0.0 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.7 1.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 RIMS2 "KIAA0751, OBOE, RAB3IP3, RIM2" ENSG00000176406 "Regulating synaptic membrane exocytosis 2" Q9UQ26 8 103500696-104256094 "Human disease related genes, Predicted intracellular proteins" Differentiation "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "adrenal gland: 50.6;brain: 48.2;retina: 102.3" "Cell type enhanced" "Detected in many" "Bipolar cells: 383.6;Cone photoreceptor cells: 706.8;Excitatory neurons: 1589.3;Inhibitory neurons: 1234.9;Oligodendrocyte precursor cells: 577.0;Rod photoreceptor cells: 1088.7" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 9.2;RT4: 7.3;SCLC-21H: 16.5;SuSa: 8.8;U-2 OS: 6.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046538, HPA066498, CAB079049" Enhanced Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 17: Basophils - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "CAB079049: , HPA046538: , HPA066498: AB_2685678" "unprognostic (2.98e-2)" "unprognostic (7.14e-2)" "unprognostic (4.47e-2)" "unprognostic (5.51e-2)" "unprognostic (2.82e-1)" "unprognostic (7.09e-3)" "unprognostic (2.02e-2)" "unprognostic (1.16e-2)" "unprognostic (7.61e-2)" "unprognostic (8.01e-3)" "unprognostic (1.40e-2)" "unprognostic (6.34e-2)" "unprognostic (1.67e-5)" "unprognostic (8.12e-4)" "unprognostic (1.04e-1)" "unprognostic (1.61e-1)" "unprognostic (9.08e-2)" 0.2 50.6 22.4 0.2 27.1 0.4 0.7 35.5 48.2 7.5 0.0 0.1 0.4 0.6 0.9 0.3 5.9 0.9 0.1 18.4 16.4 0.3 0.1 0.1 0.3 5.5 9.7 2.0 0.7 0.0 15.0 0.4 6.4 1.7 0.1 102.3 0.8 1.0 0.2 0.3 0.5 1.3 3.5 0.1 0.6 2.8 16.7 0.8 1.3 0.1 0.2 1.7 2.4 29.4 4.6 0.0 4.8 0.0 0.0 0.1 0.0 0.4 0.3 1.0 1.3 0.1 0.3 9.2 0.1 0.1 1.4 0.3 1.9 0.8 2.2 0.0 0.3 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.7 0.0 1.0 1.5 0.0 1.2 0.0 0.5 0.0 0.4 0.9 0.0 4.0 0.0 0.5 0.0 0.0 0.0 0.0 7.3 16.5 3.3 0.0 0.1 0.7 8.8 0.4 0.2 0.0 0.0 6.5 0.1 0.1 1.2 0.0 0.1 0.4 0.3 0.3 0.8 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.5 0.1 0.0 0.1 0.0 0.0 22.4 27.1 35.5 48.2 18.4 16.4 5.5 9.7 6.4 3.5 16.7 29.4 0.4 28.9 22.5 38.5 0.2 0.3 1.8 2.8 1.8 383.6 0.7 0.6 0.9 1.5 16.9 0.0 706.8 0.5 0.1 0.2 1.9 0.1 34.2 2.1 0.4 4.9 8.4 0.0 1589.3 0.0 0.3 3.7 0.0 3.7 16.4 18.0 0.7 0.3 0.3 67.3 1234.9 0.9 0.0 0.6 0.8 20.1 72.1 2.5 1.8 63.7 0.6 86.6 1.0 577.0 27.0 0.3 1.2 29.3 0.3 4.1 2.0 0.2 10.6 1088.7 0.0 0.8 1.0 34.8 15.7 0.8 0.4 0.1 2.1 0.1 1.5 1.1 RIOK2 FLJ11159 ENSG00000058729 "RIO kinase 2" Q9BVS4 5 97160867-97183247 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Cell cycle, Ribosome biogenesis" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005681 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 54: Non-specific - Microtubule organization" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" Cytosol "Plasma membrane" "HPA005681: AB_1856286" "unprognostic (6.36e-2)" "unprognostic (1.21e-1)" "unprognostic (1.13e-2)" "unprognostic (8.04e-2)" "unprognostic (1.38e-1)" "unprognostic (4.51e-2)" "unprognostic (2.71e-3)" "unprognostic (3.08e-1)" "unprognostic (3.90e-2)" "unprognostic (1.11e-1)" "unprognostic (8.76e-2)" "unprognostic (6.63e-2)" "unprognostic (1.26e-3)" "unprognostic (3.60e-1)" "unprognostic (9.98e-2)" "unprognostic (1.43e-2)" "unprognostic (1.39e-2)" 15.0 14.6 12.5 13.5 13.7 21.5 14.7 16.6 21.3 12.9 14.1 13.3 13.0 11.6 12.2 13.5 12.3 7.8 16.3 12.5 14.7 14.2 18.1 10.3 14.3 13.5 13.5 14.8 16.7 11.3 15.1 12.1 13.5 12.0 12.7 19.4 11.8 9.3 21.4 11.3 11.2 9.3 13.9 14.6 13.3 12.6 13.7 13.7 11.9 14.2 13.6 13.2 12.1 15.9 19.0 22.0 20.3 38.5 25.9 28.6 32.1 48.1 29.0 33.0 43.2 30.4 32.5 41.7 53.1 21.3 51.6 21.7 34.2 27.4 44.9 29.3 18.5 20.3 44.0 42.9 23.6 38.5 27.2 18.5 20.8 40.1 39.8 25.0 27.0 30.8 31.7 25.4 38.0 31.9 46.4 47.8 22.5 10.6 23.9 51.9 38.3 61.9 25.7 16.9 23.7 17.9 27.5 28.3 35.6 29.6 29.6 36.4 28.5 41.2 28.9 33.0 51.8 25.3 36.4 95.2 24.0 39.7 38.4 17.9 26.2 15.8 24.6 30.7 34.4 24.0 31.5 27.8 29.4 18.6 33.9 36.5 5.0 30.7 23.8 29.2 31.7 22.7 12.5 13.7 16.6 21.3 12.5 14.7 13.5 13.5 13.5 13.9 13.7 15.9 14.9 9.6 12.8 7.8 16.9 26.4 17.9 25.2 12.5 16.2 11.1 11.4 20.5 10.0 17.4 7.3 12.5 19.6 26.9 6.4 17.6 17.3 1.3 10.7 18.0 14.0 9.6 8.4 10.9 14.9 24.8 21.1 14.8 10.5 27.9 12.7 8.2 8.1 18.3 13.5 11.0 12.7 18.3 9.4 9.2 3.0 13.4 11.0 5.4 3.7 16.5 13.4 14.4 9.0 15.0 11.4 10.1 16.1 19.1 10.4 11.8 17.3 13.3 17.7 6.6 17.4 22.9 23.5 20.7 10.1 18.9 17.4 19.6 19.4 12.6 12.0 RIPK1 RIP ENSG00000137275 "Receptor interacting serine/threonine kinase 1" Q13546 6 3063824-3115187 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Host-virus interaction, Inflammatory response, Necrosis" "Kinase, Serine/threonine-protein kinase, Transferase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010302, HPA015257" Supported Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 18: Non-specific - Mitochondria" "Cluster 44: HDLM-2 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "CAB010302: AB_2178118, HPA015257: AB_1856294" "unprognostic (1.24e-1)" "unprognostic (6.83e-2)" "unprognostic (1.87e-1)" "unprognostic (7.75e-2)" "unprognostic (6.08e-2)" "unprognostic (1.01e-2)" "unprognostic (1.26e-2)" "unprognostic (1.96e-1)" "unprognostic (9.46e-2)" "unprognostic (1.46e-1)" "unprognostic (5.00e-2)" "unprognostic (3.29e-1)" "unprognostic (9.65e-3)" "unprognostic (3.44e-1)" "unprognostic (9.01e-2)" "unprognostic (1.38e-2)" "prognostic favorable (6.71e-4)" 18.5 12.0 1.9 9.3 1.9 0.5 16.2 1.8 3.8 12.8 2.4 17.5 12.3 14.5 5.3 17.6 12.8 10.6 11.8 1.8 1.9 13.7 23.6 13.5 10.1 2.2 1.9 8.5 17.4 12.2 12.3 10.9 2.0 13.7 13.0 2.4 16.4 8.9 11.7 20.7 19.9 11.9 2.0 19.4 16.5 5.3 2.0 11.9 14.4 5.0 13.0 15.5 13.7 1.9 14.4 9.8 12.9 12.4 27.6 19.2 5.5 21.4 30.8 22.8 26.7 12.4 8.0 13.8 20.9 30.1 23.2 14.3 17.9 17.2 24.3 27.8 9.4 16.7 4.5 6.9 17.2 15.6 20.1 24.8 15.1 20.4 15.3 17.6 20.6 6.2 19.4 4.6 22.0 17.8 10.7 7.7 8.8 17.4 12.7 11.8 10.9 14.5 17.3 27.2 11.3 12.2 14.7 7.8 22.4 26.0 15.2 8.7 25.1 20.6 12.1 8.2 16.4 9.8 15.3 13.5 8.9 7.0 27.7 0.1 0.4 0.9 0.6 0.9 1.0 0.3 0.9 1.7 1.0 1.2 0.7 0.7 0.0 1.5 0.5 0.5 1.7 0.8 1.9 1.9 1.8 3.8 1.8 1.9 2.2 1.9 2.0 2.0 2.0 1.9 28.6 6.4 12.0 17.3 14.7 11.0 10.3 6.6 16.5 4.4 14.7 17.8 8.6 17.2 16.7 9.2 12.5 8.9 21.9 27.1 5.9 9.4 2.0 10.5 14.0 16.7 6.6 7.2 23.1 12.9 7.7 18.3 27.0 13.4 10.8 8.7 10.0 14.6 11.6 5.0 26.7 17.7 4.1 6.7 11.1 0.8 6.8 15.3 3.6 11.2 13.8 6.6 12.3 14.6 16.2 13.8 11.7 6.0 22.3 11.3 12.7 8.7 17.4 21.4 19.7 32.5 17.9 1.2 2.8 20.5 9.9 11.9 20.8 10.6 11.3 14.5 RNF114 "PSORS12, ZNF313" ENSG00000124226 "Ring finger protein 114" Q9Y508 20 49936336-49953885 "Enzymes, Predicted intracellular proteins" "Differentiation, Spermatogenesis, Ubl conjugation pathway" "Developmental protein, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in all" 6 "Early spermatids: 1500.7;Late spermatids: 923.4;Spermatocytes: 558.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 561.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021184 Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 78: Testis - Spermatogenesis" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA021184: AB_1859185" "unprognostic (8.38e-2)" "unprognostic (3.56e-2)" "unprognostic (5.62e-2)" "prognostic unfavorable (8.10e-6)" "unprognostic (1.56e-1)" "unprognostic (2.96e-1)" "prognostic unfavorable (3.11e-4)" "unprognostic (2.50e-2)" "unprognostic (1.03e-2)" "unprognostic (2.12e-1)" "unprognostic (3.99e-1)" "unprognostic (2.70e-2)" "unprognostic (2.54e-3)" "unprognostic (1.33e-1)" "unprognostic (1.76e-1)" "prognostic favorable (3.01e-4)" "unprognostic (1.36e-2)" 32.8 32.0 43.3 29.7 48.2 51.6 31.2 46.6 45.1 37.2 41.0 45.0 42.8 28.7 32.8 30.8 34.7 28.8 37.6 40.4 44.9 48.6 49.0 37.9 39.3 47.3 46.5 39.0 52.2 30.2 28.1 35.1 46.6 33.9 40.0 16.7 41.0 34.1 83.3 24.2 40.8 25.4 47.1 52.4 35.9 166.1 47.2 39.1 37.9 52.8 37.3 28.9 28.7 49.9 83.9 80.5 42.9 43.7 84.3 57.8 118.0 73.0 86.2 153.2 64.4 241.7 67.6 39.9 142.9 40.1 91.6 66.3 62.5 74.7 90.6 73.5 44.3 51.5 50.1 173.2 73.3 95.3 59.5 51.5 68.8 58.4 39.9 52.6 36.8 69.7 98.0 46.7 45.5 281.0 82.6 98.0 42.3 67.4 114.3 85.7 45.5 73.6 83.4 67.9 63.2 45.4 88.8 561.6 118.5 45.4 149.7 86.6 47.8 134.6 62.3 71.6 87.0 93.6 107.1 79.2 76.4 63.2 76.1 112.2 97.8 86.1 48.1 92.5 53.1 63.9 52.6 48.6 75.3 71.2 61.6 50.2 100.5 57.8 112.5 61.9 68.9 92.7 43.3 48.2 46.6 45.1 40.4 44.9 47.3 46.5 46.6 47.1 47.2 49.9 47.1 48.1 53.7 13.4 69.9 107.2 127.8 103.4 63.2 24.4 50.7 55.8 46.1 41.5 101.4 69.9 12.5 91.3 61.0 61.7 72.4 107.5 1500.7 72.2 36.3 55.3 60.4 45.4 22.8 101.1 77.4 61.9 41.3 71.4 45.0 31.9 46.1 63.7 110.6 40.4 24.4 79.5 42.7 76.6 146.5 923.4 70.5 66.0 71.2 27.2 96.3 38.0 56.7 10.6 26.2 92.1 77.9 59.8 81.9 122.5 96.4 120.9 75.8 22.6 39.5 45.5 59.2 558.0 138.4 45.8 87.1 124.8 69.2 46.5 80.4 113.3 RNF149 FLJ90504 ENSG00000163162 "Ring finger protein 149" Q8NC42 2 101271219-101308701 "Enzymes, Metabolic proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Kupffer cells: 278.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "neutrophil: 619.9" "Lineage enriched" "Detected in all" 5 "granulocytes: 619.9" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011424 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Vesicles, Plasma membrane" "HPA011424: AB_1079825" "unprognostic (2.56e-2)" "unprognostic (4.70e-2)" "unprognostic (1.96e-1)" "unprognostic (3.49e-2)" "unprognostic (3.17e-2)" "unprognostic (5.17e-3)" "unprognostic (4.16e-2)" "unprognostic (4.77e-3)" "unprognostic (5.61e-2)" "unprognostic (1.43e-2)" "unprognostic (5.69e-3)" "unprognostic (1.51e-1)" "prognostic unfavorable (2.04e-8)" "unprognostic (1.39e-1)" "unprognostic (6.16e-2)" "unprognostic (2.70e-1)" "prognostic favorable (2.91e-4)" 26.7 15.2 7.7 40.3 7.5 52.3 16.3 7.7 9.7 17.7 12.3 15.7 16.8 12.4 16.3 35.5 16.9 18.9 12.5 7.6 8.9 16.3 26.6 30.5 18.3 9.9 8.5 15.9 22.3 17.9 10.4 21.8 9.6 12.6 15.8 7.8 18.3 10.1 8.5 25.6 18.2 12.9 8.5 53.1 19.1 15.8 9.1 15.2 12.2 9.4 19.6 29.1 22.7 10.9 19.9 11.4 8.8 11.3 31.6 31.3 49.7 24.0 31.8 32.1 35.8 29.0 51.6 6.1 28.3 23.9 42.9 39.0 12.5 24.6 29.7 16.9 16.6 12.4 9.9 50.0 42.1 13.4 19.2 28.9 40.0 37.9 25.1 24.7 58.9 13.0 10.7 18.0 32.4 16.9 18.8 14.0 6.1 27.1 20.0 11.5 14.2 23.4 38.0 48.0 11.5 8.5 14.4 36.0 37.2 9.5 9.7 17.8 39.6 16.2 9.1 24.5 5.3 35.5 22.5 0.2 5.2 18.6 12.2 44.0 73.6 90.3 43.8 118.1 41.8 13.2 40.0 45.3 27.9 8.5 28.2 30.2 619.9 15.3 134.1 52.5 53.8 69.8 7.7 7.5 7.7 9.7 7.6 8.9 9.9 8.5 9.6 8.5 9.1 10.9 19.9 48.1 48.1 44.7 55.2 76.9 78.1 63.5 54.7 20.4 29.7 15.9 13.0 41.5 48.4 55.2 56.3 65.2 112.4 53.1 1.9 59.1 97.9 41.8 31.9 30.0 8.5 22.7 82.8 42.2 73.0 53.5 37.2 63.1 39.2 17.3 27.1 46.2 85.9 8.4 71.6 31.7 12.2 278.6 144.2 37.2 30.7 209.0 40.9 50.6 116.5 11.6 61.8 34.7 59.6 54.3 52.3 19.5 125.5 73.5 45.9 25.8 44.8 20.7 59.2 40.5 30.1 36.6 40.3 128.3 91.6 128.1 115.7 23.8 32.8 154.1 RNF165 "Ark2C, ARKL2, RNF111L2" ENSG00000141622 "Ring finger protein 165" Q6ZSG1 18 46326809-46463140 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 7.6;retina: 18.2" "Cell type enhanced" "Detected in many" "Bipolar cells: 44.0;Cone photoreceptor cells: 100.1;Excitatory neurons: 47.4;Horizontal cells: 80.8;Inhibitory neurons: 34.4;NK-cells: 41.2;Oligodendrocyte precursor cells: 35.7;Rod photoreceptor cells: 49.1" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "AF22: 10.1;HaCaT: 7.3;HeLa: 7.5;RPMI-8226: 6.4;SCLC-21H: 13.9;SH-SY5Y: 13.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041615, HPA047798" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 62: Horizontal cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA041615: AB_2677582, HPA047798: AB_2680158" "unprognostic (6.46e-3)" "unprognostic (7.25e-2)" "unprognostic (4.55e-2)" "unprognostic (1.24e-5)" "unprognostic (3.43e-1)" "unprognostic (4.57e-2)" "unprognostic (5.18e-2)" "unprognostic (1.69e-1)" "unprognostic (1.04e-3)" "unprognostic (1.95e-1)" "unprognostic (1.23e-1)" "unprognostic (2.07e-1)" "unprognostic (1.87e-5)" "unprognostic (3.53e-3)" "unprognostic (1.90e-1)" "unprognostic (1.29e-1)" "unprognostic (1.64e-1)" 0.6 0.5 3.1 0.3 3.7 0.3 0.7 7.6 6.4 0.6 0.0 0.4 0.0 0.2 1.9 1.2 1.2 0.3 1.0 4.7 0.2 1.6 5.2 0.3 0.2 0.0 0.3 0.0 0.3 2.4 4.1 0.2 0.0 2.2 0.1 18.2 0.8 1.3 1.5 1.2 0.3 0.1 0.1 2.0 0.2 0.5 1.3 0.9 4.0 0.8 0.4 0.3 0.5 1.9 1.6 0.1 10.1 0.1 0.0 0.0 4.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.2 7.3 0.5 1.0 0.0 0.0 1.1 0.1 7.5 0.0 0.0 3.4 0.0 0.0 0.8 0.0 0.0 0.4 0.0 2.3 0.0 0.2 0.0 0.0 2.6 0.9 1.7 0.4 1.3 2.7 0.6 6.4 0.7 2.2 13.9 13.2 2.0 0.0 0.0 0.9 0.3 0.5 0.0 0.0 0.9 0.0 0.5 0.0 0.0 0.0 0.0 3.8 0.4 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.4 0.0 0.0 3.1 3.7 7.6 6.4 4.7 0.2 0.0 0.3 0.0 0.1 1.3 1.9 9.1 3.2 1.7 1.6 0.3 2.7 9.5 12.9 28.5 44.0 2.9 7.2 8.4 1.5 2.8 0.0 100.1 0.2 10.0 0.2 3.9 0.0 3.8 1.5 9.3 5.0 0.0 0.0 47.4 0.0 0.3 2.4 0.0 0.6 0.0 0.0 1.8 8.9 0.1 80.8 34.4 0.0 2.0 1.9 1.3 5.1 2.5 0.4 1.8 1.9 0.3 5.0 41.2 35.7 1.8 0.1 0.0 4.1 0.4 5.0 0.1 0.1 0.6 49.1 0.0 4.5 0.7 0.4 0.9 3.7 2.0 0.3 3.2 3.2 0.0 2.4 ROBO3 "FLJ21044, HGPPS, HGPS, RBIG1" ENSG00000154134 "Roundabout guidance receptor 3" Q96MS0 11 124865432-124881471 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Chemotaxis, Differentiation, Neurogenesis" "Developmental protein, Receptor" "Disease variant" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 6.4" "Cell type enhanced" "Detected in many" "Astrocytes: 32.3;Muller glia cells: 45.3" "Cancer enhanced" "Detected in many" "glioma: 5.0" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 12 "AF22: 18.4" "Region enhanced" "Detected in single" "cerebral cortex: 2.1" "Low region specificity" "Detected in many" HPA071053 Approved "Vesicles,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 72: Non-specific - Transcription" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Vesicles "HPA071053: " "unprognostic (1.30e-1)" "unprognostic (2.17e-1)" "unprognostic (4.95e-3)" "unprognostic (3.42e-2)" "unprognostic (3.84e-2)" "unprognostic (6.25e-2)" "unprognostic (6.95e-3)" "unprognostic (9.65e-2)" "unprognostic (1.56e-2)" "unprognostic (1.18e-1)" "unprognostic (1.32e-1)" "unprognostic (7.15e-2)" "unprognostic (3.75e-8)" "unprognostic (7.27e-3)" "unprognostic (2.21e-1)" "unprognostic (1.47e-1)" "unprognostic (4.91e-3)" 2.8 1.8 0.5 0.0 0.3 0.2 1.9 0.0 3.2 0.7 0.0 1.3 0.3 0.8 0.0 0.7 2.0 0.0 1.8 0.7 0.2 1.6 0.4 1.1 0.1 0.9 0.9 6.4 0.7 0.0 0.8 0.2 0.2 1.4 0.0 0.2 1.2 0.0 0.5 0.7 0.9 0.8 0.2 1.6 0.6 1.2 1.7 0.0 1.4 0.0 0.0 0.7 1.2 0.9 0.0 0.0 18.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.3 0.0 1.3 0.0 0.3 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.0 1.1 0.0 0.0 1.5 0.2 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.0 0.1 0.0 0.0 0.4 0.3 0.0 0.1 0.2 0.3 0.0 0.1 0.1 0.0 0.6 0.9 0.0 0.9 0.2 0.0 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.5 0.3 0.0 3.2 0.7 0.2 0.9 0.9 0.2 0.2 1.7 0.9 13.2 0.0 7.3 32.3 0.4 2.9 14.5 16.2 4.0 1.9 5.9 10.9 2.7 1.5 5.9 12.9 0.0 0.2 8.5 2.1 0.0 9.3 0.4 0.4 0.5 11.4 3.5 2.1 6.9 0.8 0.2 19.0 0.5 0.7 8.9 19.0 7.5 0.3 1.6 0.0 2.3 2.4 10.2 1.6 20.1 0.6 13.4 8.0 3.6 11.2 1.6 45.3 8.2 4.5 9.2 1.2 2.5 8.2 0.7 8.2 1.0 0.8 0.6 2.1 0.0 14.3 4.4 10.1 10.8 2.3 1.0 0.1 3.6 3.5 2.7 6.5 ROM1 "ROM, TSPAN23" ENSG00000149489 "Retinal outer segment membrane protein 1" Q03395 11 62611722-62615116 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion, Sensory transduction, Vision" "Disease variant, Retinitis pigmentosa" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 18 "retina: 1186.9" "Cell type enriched" "Detected in many" 5 "Rod photoreceptor cells: 3239.7" "Cancer enriched" "Detected in all" 6 "glioma: 14.9" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "NK-cell: 2.7" "Group enriched" "Detected in many" 4 "NK-cells: 2.7;T-cells: 1.2" "Cell line enhanced" "Detected in many" "HSkMC: 25.2;U-266/84: 31.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA028910, HPA073279" Enhanced Approved "Plasma membrane,Cytosol" No No "Cluster 22: NK-cells - Unknown function" "Cluster 77: Retina - Visual perception" "Cluster 16: U-266 - Nucleosome" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane, Cytosol" "HPA028910: AB_2672824, HPA073279: " "unprognostic (1.54e-2)" "unprognostic (1.37e-2)" "unprognostic (4.24e-2)" "unprognostic (1.11e-1)" "unprognostic (1.65e-1)" "unprognostic (2.02e-1)" "unprognostic (4.05e-1)" "prognostic favorable (2.20e-4)" "unprognostic (2.20e-1)" "unprognostic (9.87e-2)" "unprognostic (7.65e-3)" "unprognostic (3.50e-2)" "prognostic unfavorable (2.85e-6)" "unprognostic (2.61e-1)" "unprognostic (4.65e-1)" "unprognostic (1.02e-1)" "unprognostic (7.24e-2)" 12.8 7.9 57.9 2.2 60.5 1.2 9.3 56.8 67.4 9.1 48.1 9.8 1.8 7.7 4.7 7.6 10.7 4.6 8.1 54.5 59.0 7.0 7.1 6.0 2.5 67.4 61.0 13.5 3.6 5.2 7.0 1.4 62.1 8.2 2.6 1186.9 4.2 5.0 3.3 5.4 5.3 5.4 60.0 7.5 7.0 6.2 63.1 1.6 6.0 3.7 2.5 9.6 7.3 62.1 3.2 1.9 3.1 6.6 4.5 22.0 0.6 2.1 3.7 4.3 2.8 0.9 5.3 3.0 15.9 12.2 2.0 4.1 1.5 4.2 1.1 5.3 3.0 3.1 8.6 4.0 13.0 1.1 0.9 25.2 5.9 4.5 9.1 15.1 7.0 1.2 4.0 6.5 9.1 8.3 1.7 2.3 0.8 1.7 5.9 1.6 2.6 19.1 5.0 1.8 3.3 5.1 5.0 5.8 2.5 0.5 8.1 1.4 8.3 7.2 2.7 8.3 2.5 2.9 31.9 2.4 14.2 3.1 1.5 0.0 0.4 0.3 0.3 0.1 0.9 0.2 1.2 0.3 0.2 0.3 0.5 0.6 0.1 2.7 0.4 0.3 0.4 0.5 57.9 60.5 56.8 67.4 54.5 59.0 67.4 61.0 62.1 60.0 63.1 62.1 19.9 0.0 4.4 4.9 0.6 3.7 5.7 5.0 7.4 356.6 3.8 7.2 2.5 2.8 2.3 5.5 594.2 1.0 0.6 2.4 1.9 1.6 2.0 1.0 4.1 31.3 4.2 0.0 0.2 3.1 0.2 4.1 1.1 1.0 1.3 1.2 21.8 1.7 1.1 171.6 0.5 2.8 0.0 1.9 0.8 7.9 19.0 1.2 3.6 1.9 1.3 516.9 1.0 1.0 6.5 2.1 2.5 5.7 0.6 3.1 3.1 4.7 2.7 3239.7 0.0 2.5 4.3 1.6 5.1 5.3 1.0 0.7 1.5 4.0 2.9 3.1 RPGRIP1L "CORS3, FTM, JBTS7, KIAA1005, MKS5, NPHP8, PPP1R134" ENSG00000103494 "RPGRIP1 like" Q68CZ1 16 53598153-53703938 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Ciliopathy, Disease variant, Joubert syndrome, Meckel syndrome" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Endometrial ciliated cells: 40.5;Excitatory neurons: 59.8;Respiratory ciliated cells: 85.9;Spermatocytes: 43.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039405, HPA040530" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA039405: AB_10794636, HPA040530: AB_2677023" "prognostic unfavorable (6.93e-4)" "unprognostic (1.52e-1)" "unprognostic (2.19e-3)" "unprognostic (2.26e-2)" "unprognostic (3.43e-2)" "unprognostic (1.46e-2)" "unprognostic (1.26e-4)" "unprognostic (1.24e-1)" "unprognostic (1.05e-1)" "unprognostic (3.63e-1)" "unprognostic (1.05e-1)" "unprognostic (3.31e-1)" "prognostic unfavorable (5.95e-4)" "unprognostic (5.22e-3)" "unprognostic (1.52e-1)" "unprognostic (4.92e-4)" "unprognostic (5.95e-2)" 1.6 3.5 2.3 2.1 2.2 1.5 3.2 1.0 5.2 3.1 9.5 1.7 1.3 3.8 3.7 2.2 6.8 2.7 1.9 2.7 3.0 3.0 1.1 1.9 1.8 2.4 3.2 3.5 2.0 7.6 6.0 2.1 1.9 2.9 1.7 2.9 1.7 2.8 1.0 1.9 0.9 3.5 1.0 0.9 1.9 13.5 3.5 2.6 4.6 1.4 1.8 2.2 1.8 3.2 11.8 13.7 11.6 10.7 13.9 13.3 5.6 12.7 7.9 9.8 2.7 7.1 9.5 7.5 8.5 11.1 7.8 12.5 9.4 11.6 19.1 4.6 7.2 2.8 12.1 7.5 6.0 6.7 5.0 8.1 6.9 11.4 6.9 11.4 8.9 10.0 7.2 4.3 14.8 4.5 11.2 4.7 7.4 3.7 6.3 19.3 15.9 9.4 14.0 3.1 19.9 7.5 14.3 6.4 5.3 6.7 10.0 5.7 7.8 12.2 8.6 9.7 11.0 5.4 6.9 13.1 18.9 3.9 7.3 0.7 0.2 0.3 1.2 0.3 1.2 1.1 0.8 1.0 0.2 1.5 0.8 1.8 0.6 0.8 0.3 0.7 0.7 0.4 2.3 2.2 1.0 5.2 2.7 3.0 2.4 3.2 1.9 1.0 3.5 3.2 3.1 6.4 4.8 15.7 2.9 4.6 2.8 11.1 4.6 5.5 6.9 8.0 9.8 1.5 15.1 11.0 8.4 5.5 1.5 1.3 17.6 7.4 21.5 40.5 20.7 3.9 0.0 3.0 59.8 3.3 7.4 12.9 5.1 8.6 7.0 12.9 2.5 3.8 2.9 3.3 36.6 5.6 4.1 1.2 3.1 12.0 4.7 1.9 1.8 9.4 1.8 6.3 2.1 14.1 8.6 3.3 0.5 6.4 2.1 1.7 0.2 19.8 85.9 8.7 6.6 7.8 9.7 43.2 11.2 4.7 5.4 1.6 2.7 11.5 4.4 2.4 RPSA "37LRP, LAMR1, LRP, p40, SA" ENSG00000168028 "Ribosomal protein SA" P08865 3 39406716-39412542 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins, Ribosomal proteins" "Host-virus interaction" "Host cell receptor for virus entry, Receptor, Ribonucleoprotein, Ribosomal protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" CAB009561 Approved Supported "Plasma membrane,Cytosol" NA NA 1200000 "Cluster 30: Non-specific - Translation" "Cluster 50: Non-specific - Ribosome" "Cluster 30: Epithelial cell lines - Translation" "Cluster 32: Non-specific - Translation" "Plasma membrane, Cytosol" "CAB009561: AB_2182543" "unprognostic (3.67e-3)" "unprognostic (2.92e-1)" "unprognostic (3.97e-2)" "unprognostic (3.72e-2)" "unprognostic (5.38e-2)" "unprognostic (5.10e-2)" "unprognostic (5.84e-3)" "unprognostic (2.54e-1)" "unprognostic (1.69e-1)" "unprognostic (2.36e-2)" "unprognostic (8.56e-2)" "unprognostic (7.50e-2)" "unprognostic (2.91e-2)" "unprognostic (3.18e-1)" "unprognostic (2.77e-1)" "unprognostic (1.73e-1)" "unprognostic (1.46e-1)" 1063.0 929.1 813.4 685.7 824.8 1574.8 1068.4 782.0 979.1 1260.0 761.8 1158.4 605.8 1022.1 351.0 1922.5 1128.3 372.5 783.9 778.6 794.3 905.9 972.5 894.3 1281.4 817.8 809.6 2153.7 2616.3 605.5 813.4 468.8 812.9 1212.6 872.2 273.3 1039.7 446.9 1087.1 1529.4 1133.1 718.3 842.4 1525.8 1209.3 358.0 831.9 1259.9 862.6 730.4 1466.4 1127.5 1293.1 821.5 1800.4 1646.5 1367.5 2265.9 1203.3 2661.2 2155.0 1251.2 2005.9 2775.9 1611.8 1811.6 1513.7 3949.6 737.0 2535.3 747.6 695.4 2983.8 2945.7 2402.3 1459.6 1599.6 1783.6 1390.5 1750.2 2322.7 2546.4 1649.2 3043.3 4729.8 2147.2 3475.3 2030.8 2942.7 2343.5 1909.3 1883.8 2031.1 1282.1 3031.0 1960.4 4574.2 2756.9 2755.1 1412.2 1958.4 2974.8 2004.4 814.2 985.3 1989.0 674.8 5156.5 2202.9 1843.5 1509.0 3544.5 1156.6 845.2 1545.8 1422.3 3102.3 1440.6 2363.4 2437.5 1355.7 2481.7 1143.9 98.3 240.5 56.7 572.9 294.6 993.1 1010.3 942.1 758.8 654.2 951.8 1036.2 936.1 34.3 726.0 247.5 723.6 765.5 1499.7 813.4 824.8 782.0 979.1 778.6 794.3 817.8 809.6 812.9 842.4 831.9 821.5 532.1 519.2 800.2 10.7 2802.5 1802.5 2606.9 1585.5 2040.3 270.4 1864.7 1423.4 64.0 1095.2 906.4 325.5 95.9 2852.5 1768.9 625.4 992.0 1598.4 144.3 536.7 1178.5 891.2 1033.6 1733.9 21.3 3417.4 4473.1 927.1 821.6 747.7 778.4 1654.5 937.3 717.7 1608.4 173.3 21.5 1847.0 455.7 1304.9 1469.6 283.7 1240.5 1086.9 738.2 12.2 1605.2 621.1 1858.9 19.1 29.3 1889.5 1184.2 747.4 1501.8 2136.7 724.4 1257.1 476.2 364.4 473.3 1053.5 1002.2 352.2 1255.8 2879.8 1916.2 2420.7 2100.0 1539.2 2442.4 2884.6 RSBN1L "FLJ42526, FLJ45813, MGC71764" ENSG00000187257 "Round spermatid basic protein 1 like" Q6PCB5 7 77696459-77783022 "Cancer-related genes, Predicted intracellular proteins" "Dioxygenase, Oxidoreductase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Rod photoreceptor cells: 349.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 60.6" "Lineage enriched" "Detected in all" 4 "granulocytes: 60.6" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020406, HPA020413" Approved Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 34: Non-specific - Transcription" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" "Nuclear speckles" "Plasma membrane" "HPA020406: AB_1856488, HPA020413: AB_2253910" "unprognostic (2.02e-1)" "unprognostic (2.61e-2)" "unprognostic (2.41e-1)" "unprognostic (1.72e-1)" "unprognostic (1.34e-1)" "unprognostic (3.62e-2)" "unprognostic (2.43e-2)" "prognostic favorable (3.74e-4)" "unprognostic (1.27e-2)" "unprognostic (3.78e-2)" "unprognostic (1.25e-1)" "unprognostic (9.02e-2)" "unprognostic (7.30e-3)" "unprognostic (1.93e-1)" "unprognostic (1.46e-1)" "unprognostic (2.25e-3)" "unprognostic (1.53e-3)" 7.3 6.4 8.7 11.5 9.1 8.2 12.1 19.0 12.1 10.3 10.2 11.3 9.0 12.5 10.3 10.8 9.5 7.3 5.6 8.5 10.5 9.1 11.3 10.5 16.1 8.2 9.0 14.5 11.2 10.3 6.9 9.9 8.6 10.3 11.7 30.2 9.6 11.4 8.2 7.8 10.4 11.0 9.0 15.0 11.0 26.3 8.6 18.3 16.5 7.6 15.0 9.6 8.2 11.6 15.8 11.9 19.6 34.5 13.4 17.0 9.5 11.5 12.4 16.0 18.2 14.9 27.6 32.4 4.4 12.0 20.2 13.4 26.8 15.0 22.8 17.7 14.4 25.8 18.4 14.7 11.3 32.1 23.3 12.2 10.7 14.7 16.0 12.1 13.5 21.2 35.7 33.0 16.8 18.2 27.7 32.1 14.0 20.3 10.6 28.3 19.6 34.2 10.0 20.5 22.9 24.0 17.5 31.4 12.6 19.9 19.2 16.9 12.9 23.9 21.9 14.5 17.7 14.7 16.7 51.6 11.4 29.2 16.0 21.6 7.4 13.5 9.5 5.8 7.3 11.0 8.4 7.1 4.4 13.5 7.8 8.6 60.6 6.4 6.7 13.9 9.3 2.6 8.7 9.1 19.0 12.1 8.5 10.5 8.2 9.0 8.6 9.0 8.6 11.6 53.6 57.7 60.3 27.1 85.0 78.8 102.1 76.1 88.8 246.8 52.1 57.3 22.1 61.5 84.4 55.2 235.6 52.7 101.5 77.1 39.2 38.1 271.3 55.5 63.3 60.8 77.5 47.7 44.3 50.4 34.1 55.6 51.5 45.6 70.3 51.3 49.2 56.5 43.7 158.2 47.5 104.6 57.0 48.1 69.0 85.2 101.5 46.4 64.0 34.7 59.0 83.2 132.8 53.8 50.1 35.1 62.7 119.6 74.6 56.7 49.6 28.4 72.0 349.9 72.3 44.2 73.0 108.0 156.7 56.2 75.3 38.7 90.2 61.7 79.1 84.0 RSPH3 "dJ111C20.1, RSHL2, RSP3" ENSG00000130363 "Radial spoke head 3" 6 158972871-159000202 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 149.3;Respiratory ciliated cells: 120.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 10.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039109 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 18: U-2197 - ECM organization" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "HPA039109: AB_10794423" "unprognostic (6.18e-3)" "unprognostic (3.62e-3)" "unprognostic (4.54e-2)" "unprognostic (6.20e-2)" "unprognostic (1.88e-1)" "unprognostic (9.18e-2)" "unprognostic (1.14e-2)" "unprognostic (1.65e-1)" "unprognostic (1.15e-1)" "unprognostic (6.74e-3)" "unprognostic (6.98e-2)" "unprognostic (2.52e-1)" "prognostic favorable (2.19e-4)" "unprognostic (5.89e-2)" "unprognostic (1.67e-1)" "unprognostic (5.14e-2)" "unprognostic (1.79e-2)" 2.9 4.7 0.8 2.2 1.0 1.6 3.7 0.2 4.7 3.9 14.5 4.2 5.9 3.4 4.6 5.7 6.1 3.3 3.8 2.0 1.0 6.3 2.7 4.6 1.4 1.9 2.6 3.4 4.3 13.2 3.5 3.1 1.5 5.2 3.7 6.7 4.4 4.1 1.5 3.8 5.6 3.7 1.6 2.3 4.1 9.9 1.1 1.8 7.6 2.2 2.0 2.9 3.0 1.6 8.5 3.7 2.1 4.9 4.8 6.3 2.2 6.2 7.0 1.9 2.8 1.2 4.6 1.7 4.8 7.2 6.3 6.1 1.4 5.6 2.8 4.4 2.9 2.2 3.9 2.6 4.6 2.4 1.6 7.1 9.5 3.8 6.9 10.0 2.5 2.5 2.8 2.6 4.5 4.3 1.5 2.7 1.2 3.8 2.7 2.2 0.3 1.6 8.6 2.6 2.8 4.0 11.6 3.8 2.2 2.4 4.7 5.3 5.4 2.0 5.5 4.8 3.0 2.9 6.1 1.2 10.1 2.9 3.9 0.9 4.0 0.6 0.6 3.0 1.2 0.9 0.9 1.2 4.0 2.4 0.7 1.1 10.5 1.7 7.0 4.6 1.3 1.5 0.8 1.0 0.2 4.7 2.0 1.0 1.9 2.6 1.5 1.6 1.1 1.6 2.3 25.6 17.9 15.0 4.0 7.4 17.2 19.1 6.2 14.2 12.2 7.6 17.5 17.2 25.1 22.0 35.5 10.3 5.7 25.6 13.7 15.8 149.3 67.0 6.9 6.0 13.1 2.1 32.8 10.2 11.4 7.6 10.2 12.7 2.5 9.2 7.9 8.4 10.1 3.3 18.5 17.6 16.2 9.5 16.5 62.9 14.0 12.6 7.2 4.7 8.3 14.4 4.1 6.0 3.5 13.1 21.1 17.7 5.7 18.4 33.1 19.7 120.4 32.5 6.6 5.9 10.2 57.3 10.9 18.6 8.8 5.9 6.1 12.2 13.1 23.1 S100A16 "DT1P1A7, MGC17528, S100F" ENSG00000188643 "S100 calcium binding protein A16" Q96FQ6 1 153606886-153613145 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 2477.7" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 995.4;Pancreatic endocrine cells: 1307.3;Prostatic glandular cells: 1141.1;Squamous epithelial cells: 1028.7;Suprabasal keratinocytes: 908.8;Theca cells: 1528.4;Urothelial cells: 1522.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 1369.9;SK-BR-3: 1618.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA045841 Enhanced Approved "Plasma membrane,Cytosol" NA NA 190000 "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 16: Pancreatic endocrine cells - Mixed function" Cytosol "Plasma membrane" "HPA045841: AB_10966282" "unprognostic (9.86e-3)" "unprognostic (1.69e-1)" "unprognostic (2.23e-2)" "unprognostic (3.06e-1)" "unprognostic (1.71e-1)" "unprognostic (7.03e-2)" "prognostic unfavorable (3.18e-4)" "prognostic unfavorable (3.14e-5)" "unprognostic (1.70e-1)" "unprognostic (4.59e-1)" "prognostic unfavorable (2.04e-4)" "unprognostic (2.60e-1)" "prognostic unfavorable (3.91e-5)" "unprognostic (1.01e-1)" "unprognostic (1.92e-1)" "unprognostic (3.45e-2)" "unprognostic (5.29e-3)" 166.8 79.1 81.3 61.9 79.8 0.8 159.7 78.6 98.0 333.0 70.8 139.7 121.5 78.4 19.8 2477.7 68.2 81.6 122.3 79.8 80.1 219.0 209.9 161.3 28.4 104.2 80.9 83.4 41.0 76.6 42.0 71.8 84.9 77.8 105.0 7.0 438.1 38.1 51.7 474.9 109.8 79.0 84.8 118.5 100.4 60.3 103.4 25.0 72.4 52.1 205.0 163.2 713.3 84.6 670.4 318.1 16.0 36.7 102.5 386.8 42.8 367.9 341.4 302.7 265.2 315.4 366.1 0.3 577.5 553.0 69.0 479.6 1.1 839.2 175.3 1.9 0.6 0.4 260.5 90.8 117.5 0.2 0.9 182.7 787.6 731.6 567.9 390.9 1369.9 0.0 8.5 0.8 677.3 918.7 0.9 1.4 69.0 1171.0 887.9 0.9 187.4 1.8 1150.3 236.1 0.8 1.9 267.6 1618.0 55.7 140.5 504.7 3.5 743.9 178.2 289.5 171.5 848.6 0.5 3.5 2.4 525.0 0.9 122.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 81.3 79.8 78.6 98.0 79.8 80.1 104.2 80.9 84.9 84.8 103.4 84.6 275.6 38.5 25.5 10.4 6.8 633.9 995.4 531.6 157.6 0.5 225.4 191.3 33.0 124.4 290.6 108.5 2.1 20.3 4.4 500.7 72.4 610.9 4.9 50.9 172.5 293.5 139.0 16.0 0.0 193.9 8.7 112.2 96.8 128.5 19.1 154.1 365.9 132.7 5.0 0.0 0.1 286.4 164.8 15.7 95.4 17.4 67.1 7.4 112.1 5.6 7.2 72.5 0.0 7.5 0.7 1307.3 610.0 61.3 5.6 1141.1 353.3 169.7 48.6 2.1 6.6 70.9 91.2 8.0 1.3 1028.7 908.8 8.2 12.9 1528.4 320.2 1522.5 S100A6 "2A9, CABP, CACY, PRA" ENSG00000197956 "S100 calcium binding protein A6" P06703 1 153534599-153536244 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 37545.1;Urothelial cells: 17431.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "OE19: 17071.6;RPTEC TERT1: 20988.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002601, HPA007575, CAB040549, CAB047354" Enhanced Enhanced "Plasma membrane,Cytosol" NA NA 7000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "CAB002601: , CAB040549: , CAB047354: , HPA007575: AB_1079859" "unprognostic (8.80e-3)" "unprognostic (6.96e-2)" "unprognostic (2.31e-1)" "unprognostic (2.47e-2)" "unprognostic (1.19e-1)" "unprognostic (1.19e-1)" "unprognostic (1.23e-3)" "unprognostic (1.36e-1)" "unprognostic (1.27e-1)" "unprognostic (3.51e-1)" "unprognostic (6.86e-3)" "unprognostic (1.66e-1)" "unprognostic (3.59e-1)" "unprognostic (1.10e-1)" "unprognostic (2.88e-1)" "unprognostic (1.46e-2)" "prognostic favorable (7.56e-4)" 1873.9 666.6 435.5 1129.7 452.5 2003.6 1499.2 456.2 549.9 2306.1 425.9 2872.2 1504.1 1058.4 404.8 1300.4 879.9 1485.5 1046.0 425.8 593.7 2326.6 91.9 2216.9 365.1 520.2 488.9 556.8 204.2 68.4 311.2 709.2 489.1 827.7 2252.2 36.6 1123.5 1169.3 478.1 858.6 1367.0 965.1 488.8 519.1 1586.3 170.1 573.3 191.6 970.0 1010.8 504.8 3867.5 1276.0 530.4 3666.6 4412.8 4.3 330.6 7597.2 10482.0 9.3 4560.1 13403.9 2582.7 3352.7 273.3 8022.5 4.5 1319.7 7774.8 2078.7 1589.3 80.7 7340.5 1322.0 1340.0 1.6 731.2 2579.1 255.8 2730.2 28.1 458.7 4550.0 6406.8 2638.7 4734.2 3259.1 6078.3 0.7 3.2 12.3 7052.7 589.4 11.4 292.3 9.6 17071.6 7563.4 5.5 463.0 1250.1 20988.4 3918.8 1019.8 142.6 6251.9 6380.9 4628.4 3.7 835.3 1095.9 7473.3 2228.2 489.8 4463.8 7452.6 8.8 11.9 15.5 8619.0 728.4 4773.0 5517.3 6053.2 2413.8 1806.1 3258.0 1983.1 937.8 1664.9 1773.1 4240.8 583.7 1037.2 1378.3 9637.7 297.4 3066.5 2145.0 2217.6 8320.4 435.5 452.5 456.2 549.9 425.8 593.7 520.2 488.9 489.1 488.8 573.3 530.4 1177.8 4708.3 2663.1 17.6 343.0 1488.3 6868.7 7856.4 2416.5 4.9 1494.4 1445.2 326.6 1474.1 7013.9 8165.9 0.0 1368.2 999.9 8832.0 7446.5 6206.3 21.3 1148.6 3473.2 1801.5 2035.6 637.5 14.7 9903.1 2440.0 4102.1 2276.3 814.3 1817.4 126.3 946.3 21.6 2430.3 58.9 7.1 6823.9 5706.7 2853.5 7378.0 115.0 3013.4 3110.9 3070.0 30.0 6073.8 168.0 926.9 7.5 23.0 37545.1 9094.3 1143.8 346.6 9900.7 8570.5 224.3 4962.3 8.7 131.5 3234.0 2978.8 28.7 13.2 1718.7 997.6 1573.4 1283.0 5881.5 3218.9 17431.0 SAMHD1 "AGS5, HDDC1, Mg11, MOP-5, SBBI88" ENSG00000101347 "SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1" Q9Y3Z3 20 36890229-36951843 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Antiviral defense, DNA damage, DNA repair, DNA replication, Host-virus interaction, Immunity, Innate immunity" "Allosteric enzyme, Hydrolase" "Aicardi-Goutieres syndrome, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "dendritic cells: 214.2;Endometrial ciliated cells: 173.8;Kupffer cells: 280.2;Macrophages: 326.4;monocytes: 257.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC diff: 510.8;BJ hTERT+ SV40 Large T+: 165.8;BJ hTERT+ SV40 Large T+ RasG12V: 187.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA047072 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA 91000 "Cluster 28: Myeloid DCs - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Nucleoplasm "Plasma membrane" "HPA047072: AB_2679921" "unprognostic (1.09e-1)" "unprognostic (7.30e-3)" "unprognostic (1.65e-2)" "unprognostic (3.85e-2)" "unprognostic (1.28e-1)" "unprognostic (1.91e-2)" "unprognostic (2.15e-1)" "unprognostic (4.07e-2)" "unprognostic (2.03e-1)" "unprognostic (3.63e-1)" "unprognostic (1.88e-1)" "unprognostic (1.04e-1)" "prognostic unfavorable (5.12e-4)" "unprognostic (1.44e-1)" "unprognostic (9.06e-2)" "unprognostic (3.18e-2)" "unprognostic (2.72e-2)" 79.5 39.9 11.9 94.3 12.4 11.5 65.7 11.6 12.2 39.1 33.2 58.4 29.4 33.0 9.1 45.8 81.8 40.2 60.5 11.4 16.6 12.2 26.1 68.0 78.0 16.8 15.0 38.0 42.2 14.0 21.7 36.0 17.9 26.3 28.8 5.5 32.6 18.1 23.8 27.8 55.2 44.1 17.6 94.2 45.0 12.6 18.0 29.3 31.7 20.7 51.2 55.3 39.9 26.4 29.9 10.9 3.7 15.6 510.8 101.8 5.5 10.8 37.7 165.8 187.8 39.1 11.2 64.4 19.9 14.4 94.9 21.2 34.7 27.8 30.9 17.4 20.6 5.3 18.8 30.9 39.3 28.2 5.1 96.4 1.0 45.3 1.9 13.3 26.4 0.0 13.7 18.8 5.4 12.0 0.0 19.2 7.9 18.3 25.9 2.8 21.7 35.3 15.7 8.2 23.0 4.2 20.2 10.2 28.2 4.7 20.5 125.4 13.9 11.5 13.5 25.1 28.5 7.3 20.3 21.7 14.5 3.2 7.1 1.4 147.7 4.8 52.2 174.4 47.0 4.5 55.7 53.3 278.6 3.1 55.5 47.6 18.5 56.2 167.0 96.4 95.8 144.3 11.9 12.4 11.6 12.2 11.4 16.6 16.8 15.0 17.9 17.6 18.0 26.4 48.7 28.9 25.5 4.2 19.4 6.4 2.3 7.8 5.7 5.5 6.9 5.8 17.3 14.3 35.3 1.8 4.2 2.6 214.2 2.6 0.0 10.3 3.3 173.8 12.7 44.3 6.0 30.7 8.6 10.2 3.3 71.4 13.3 40.6 12.6 10.5 42.5 20.1 137.2 6.7 8.5 5.7 8.2 280.2 52.3 4.8 82.3 326.4 5.4 36.5 257.9 25.1 116.4 14.1 3.5 7.5 31.3 96.3 54.8 1.9 1.1 1.9 104.4 2.9 59.2 9.6 31.9 10.2 4.9 12.1 5.8 2.9 102.6 9.7 5.5 4.9 SAMSN1 "HACS1, NASH1, SASH2, SH3D6B, SLy2" ENSG00000155307 "SAM domain, SH3 domain and nuclear localization signals 1" Q9NSI8 21 14485228-14658821 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 192.9;lymphoid tissue: 80.1" "Cell type enhanced" "Detected in many" "granulocytes: 1174.1;Langerhans cells: 317.9;Macrophages: 414.6;monocytes: 829.9;T-cells: 332.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "basophil: 314.2" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 4 "HEL: 273.7;K-562: 331.6;Karpas-707: 137.3" "Region enriched" "Detected in many" 6 "olfactory bulb: 20.7" "Low region specificity" "Detected in all" "HPA010645, HPA017055, HPA046639" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 1: K-562 - Erythropoiesis" "Cluster 41: Macrophages - Immune response" "Plasma membrane" Nucleoplasm "HPA010645: AB_1856559, HPA017055: AB_1856560, HPA046639: AB_2679732" "unprognostic (7.62e-3)" "unprognostic (1.46e-2)" "unprognostic (1.03e-2)" "unprognostic (3.11e-2)" "unprognostic (2.44e-1)" "unprognostic (3.91e-2)" "unprognostic (1.41e-1)" "unprognostic (1.01e-1)" "unprognostic (2.17e-1)" "unprognostic (6.13e-2)" "unprognostic (2.10e-2)" "unprognostic (1.28e-1)" "prognostic unfavorable (4.52e-6)" "unprognostic (9.14e-2)" "unprognostic (3.05e-2)" "unprognostic (2.17e-1)" "unprognostic (1.68e-2)" 32.3 6.7 2.4 80.1 2.8 192.9 4.7 3.3 4.9 5.7 4.2 11.0 7.0 3.4 1.9 5.3 6.3 22.7 4.5 2.5 3.5 4.2 17.5 22.9 35.4 6.2 4.5 1.3 3.1 2.0 2.1 15.5 6.1 3.9 15.3 12.7 2.8 2.2 0.7 1.5 15.1 10.8 5.1 32.0 9.3 1.2 4.6 22.4 2.2 1.2 41.0 39.7 2.5 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.1 0.0 0.0 0.0 0.0 1.8 0.0 14.0 0.0 273.7 0.0 0.0 0.0 32.5 12.7 0.1 0.0 0.0 37.9 10.2 3.6 4.8 331.6 137.3 0.0 0.0 15.9 39.5 0.1 0.0 0.2 26.8 0.3 20.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.8 35.0 0.0 0.0 0.0 0.0 58.2 0.5 0.3 1.4 20.7 0.0 314.2 38.7 234.6 22.1 52.3 15.4 27.3 42.8 33.3 25.0 15.4 26.8 19.1 49.4 18.0 83.0 0.9 60.3 33.6 2.4 2.8 3.3 4.9 2.5 3.5 6.2 4.5 6.1 5.1 4.6 8.9 4.8 22.4 54.9 0.7 127.5 15.6 1.1 0.0 1.8 64.9 2.7 3.0 1.2 1.5 11.2 36.8 0.0 0.5 147.9 0.7 0.0 0.6 0.0 0.8 0.2 8.0 0.0 13.7 1.0 6.5 0.7 11.3 10.7 0.6 1174.1 0.1 4.6 1.8 62.0 0.0 0.8 0.8 0.0 183.7 317.9 0.4 0.6 414.6 21.4 131.2 829.9 1.6 24.7 2.5 0.6 0.7 1.1 0.0 119.3 0.5 0.0 0.5 8.0 4.7 0.0 2.2 3.7 0.1 0.2 1.2 13.2 0.5 332.8 0.1 0.9 0.9 SCIN KIAA1905 ENSG00000006747 Scinderin Q9Y6U3 7 12570577-12660182 "Plasma proteins, Predicted intracellular proteins" "Actin capping, Actin-binding" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 46.4;kidney: 47.1;placenta: 77.6" "Cell type enhanced" "Detected in many" "Collecting duct cells: 334.8;Distal enterocytes: 100.7;Early spermatids: 124.6;Hofbauer cells: 99.9;Paneth cells: 138.6;Proximal enterocytes: 318.4" "Cancer enhanced" "Detected in many" "renal cancer: 13.5" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 5 "RPTEC TERT1: 94.3;SK-BR-3: 102.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA020518, HPA024264" Enhanced Approved "Plasma membrane,Cytosol" No No 2300000 "Cluster 17: Basophils - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 45: Enterocytes - Digestion" "Plasma membrane" Cytosol "HPA020518: AB_1856619, HPA024264: AB_1856621" "unprognostic (3.68e-1)" "unprognostic (4.98e-2)" "unprognostic (5.05e-1)" "unprognostic (2.47e-1)" "unprognostic (1.50e-1)" "unprognostic (5.98e-2)" "unprognostic (3.64e-5)" "unprognostic (1.31e-2)" "unprognostic (3.09e-1)" "unprognostic (3.77e-2)" "unprognostic (1.25e-1)" "unprognostic (1.24e-1)" "prognostic favorable (4.26e-8)" "unprognostic (3.87e-1)" "unprognostic (4.99e-2)" "unprognostic (3.13e-2)" "unprognostic (3.18e-1)" 2.9 1.0 3.6 1.3 4.5 1.3 0.9 4.6 5.3 1.3 2.9 18.3 26.7 1.3 0.5 17.9 4.1 2.8 0.3 3.8 4.8 47.1 0.3 4.1 0.6 9.4 6.8 0.7 0.9 1.1 2.6 77.6 9.7 3.2 16.0 2.4 10.7 1.1 0.5 3.6 46.4 1.1 7.1 0.5 19.6 7.1 5.7 0.6 1.1 1.7 4.3 3.5 1.3 12.3 0.2 0.2 0.2 0.8 0.0 0.0 0.3 0.3 0.1 0.1 0.5 0.1 0.5 0.3 0.2 0.0 0.1 0.2 0.1 0.0 0.0 0.1 10.4 0.1 1.3 0.2 0.1 0.4 0.3 0.2 1.4 0.4 0.0 0.2 0.1 0.2 0.4 20.8 0.5 0.5 0.2 1.4 0.2 5.7 3.2 0.3 0.5 0.1 94.3 3.6 4.1 0.2 1.0 102.8 0.1 0.7 10.8 0.6 0.1 0.3 0.8 2.0 0.2 3.4 0.2 0.2 0.1 0.4 0.1 1.2 0.2 0.2 0.3 0.2 0.3 1.1 0.3 0.3 0.2 0.5 0.3 0.3 0.6 0.4 0.3 0.3 0.2 0.1 3.6 4.5 4.6 5.3 3.8 4.8 9.4 6.8 9.7 7.1 5.7 12.3 3.5 0.0 23.6 0.0 0.7 2.8 1.5 1.6 0.6 3.2 3.3 1.7 1.2 4.3 8.5 334.8 0.0 23.8 0.2 100.7 82.2 0.6 124.6 25.5 1.0 6.7 9.1 0.0 0.1 0.2 4.7 2.7 55.5 11.3 39.9 0.0 0.4 0.1 99.9 0.0 0.2 62.9 46.8 3.0 0.5 87.8 0.3 2.8 10.6 15.0 1.7 0.4 0.0 0.0 0.3 8.6 138.6 1.2 1.4 4.7 318.4 3.2 17.2 3.0 0.0 0.9 1.0 3.8 5.5 26.6 6.5 65.8 2.2 0.1 21.4 23.1 SCNN1D "dNaCh, ENaCdelta" ENSG00000162572 "Sodium channel epithelial 1 subunit delta" P51172 1 1280436-1292029 "FDA approved drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "testis: 35.5" "Cell type enhanced" "Detected in many" "Astrocytes: 10.7;Early spermatids: 10.5" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-266/70: 9.3" "Low region specificity" "Detected in all" HPA026884 Enhanced Supported "Plasma membrane,Actin filaments" NA NA "Cluster 43: Testis - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane, Actin filaments" "HPA026884: AB_10601501" "unprognostic (2.08e-2)" "unprognostic (2.08e-1)" "unprognostic (7.39e-4)" "unprognostic (1.06e-2)" "unprognostic (2.74e-1)" "prognostic favorable (1.60e-4)" "unprognostic (1.44e-2)" "unprognostic (1.81e-1)" "unprognostic (2.08e-2)" "unprognostic (1.14e-1)" "prognostic favorable (1.32e-4)" "unprognostic (5.27e-2)" "prognostic unfavorable (6.67e-5)" "unprognostic (3.13e-1)" "unprognostic (4.18e-2)" "unprognostic (2.13e-1)" "unprognostic (7.06e-2)" 5.6 7.1 10.3 1.7 10.4 3.2 6.0 11.7 18.1 11.1 5.9 9.4 5.2 8.0 0.9 4.0 14.0 1.2 6.2 9.7 7.5 7.7 13.7 3.7 2.3 10.7 8.5 14.7 4.8 0.7 18.5 1.1 10.9 9.7 0.3 1.7 5.8 1.7 3.4 4.7 7.6 0.8 6.9 8.0 6.3 35.5 9.9 0.9 6.3 1.4 0.7 5.1 7.6 11.7 0.5 4.2 1.6 4.3 1.1 0.6 0.7 2.8 0.8 1.3 1.5 0.8 2.4 3.0 1.5 1.2 2.2 0.7 0.7 0.6 0.2 5.8 2.5 0.4 5.9 1.1 1.1 0.1 2.9 1.8 0.9 2.3 0.0 1.8 0.4 5.5 2.1 7.0 0.3 1.5 1.2 2.0 0.8 0.5 3.0 8.1 0.3 0.7 0.6 0.2 2.2 3.1 1.2 1.2 1.9 0.6 5.4 1.6 1.2 2.6 2.1 4.1 0.9 9.3 0.6 2.5 2.3 5.2 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 10.3 10.4 11.7 18.1 9.7 7.5 10.7 8.5 10.9 6.9 9.9 11.7 1.7 3.2 2.3 10.7 1.0 0.8 0.2 1.2 1.2 3.7 2.2 3.4 4.0 0.0 1.7 0.0 4.2 0.1 0.6 1.0 0.0 0.5 10.5 0.6 2.1 0.6 1.2 2.7 5.2 0.5 0.4 1.7 4.1 1.3 2.5 3.2 0.7 3.5 0.4 5.0 6.0 0.4 0.0 0.8 0.5 4.0 0.9 1.1 0.0 1.0 0.1 1.4 0.0 4.5 5.4 2.0 3.8 1.9 0.7 0.1 3.9 0.7 1.9 2.8 0.0 1.8 1.5 2.8 2.2 0.8 1.6 0.0 1.0 0.5 0.9 0.3 SCNN1G "ENaCgamma, SCNEG" ENSG00000166828 "Sodium channel epithelial 1 subunit gamma" P51170 16 23182745-23216883 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted membrane proteins, Transporters" "Ion transport, Sensory transduction, Sodium transport, Taste, Transport" "Ion channel, Sodium channel" "Disease variant, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "kidney: 42.4" "Cell type enriched" "Detected in some" 4 "Collecting duct cells: 90.1" "Cancer enhanced" "Detected in many" "urothelial cancer: 15.6" "Region enriched" "Detected in single" 6 "cerebellum: 4.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 7 "hTCEpi: 46.8;RT4: 21.7" "Region enriched" "Detected in single" 13 "cerebellum: 2.5" "Not detected" "Not detected" HPA071194 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA071194: AB_2686359" "unprognostic (2.90e-1)" "unprognostic (5.21e-3)" "unprognostic (5.79e-2)" "unprognostic (4.31e-2)" "unprognostic (1.92e-3)" "unprognostic (1.71e-3)" "unprognostic (1.97e-1)" "unprognostic (4.85e-2)" "unprognostic (7.84e-3)" "unprognostic (1.90e-1)" "unprognostic (2.57e-2)" "prognostic unfavorable (3.20e-7)" "unprognostic (2.80e-2)" "unprognostic (1.34e-1)" "unprognostic (2.63e-1)" "unprognostic (4.17e-3)" 0.7 0.2 0.4 0.0 0.3 0.3 2.3 4.4 0.2 16.0 0.2 10.3 0.0 1.8 0.7 9.9 0.4 0.0 0.0 0.8 0.2 42.4 0.0 7.4 0.0 0.2 0.2 0.0 3.2 0.0 3.8 0.5 0.4 13.8 1.2 0.2 17.7 3.4 0.0 9.7 0.4 0.1 0.0 0.0 10.1 0.1 0.1 2.0 5.7 0.0 1.2 1.4 15.3 0.3 1.1 0.0 0.0 0.0 0.0 0.0 5.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 46.8 0.0 0.6 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 2.9 0.0 0.0 0.1 0.0 21.7 1.5 0.0 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.4 0.3 4.4 0.2 0.8 0.2 0.2 0.2 0.4 0.0 0.1 0.3 0.4 19.2 4.2 0.0 0.0 0.4 4.7 8.8 19.9 0.0 0.8 1.3 0.8 0.0 17.4 90.1 0.0 0.2 0.0 3.4 0.0 2.0 0.0 9.8 1.1 0.1 0.0 0.0 0.2 1.7 0.0 0.4 15.3 18.6 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.2 10.2 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.5 0.1 0.5 1.1 0.0 0.1 5.3 0.0 0.2 1.9 0.0 0.0 0.0 0.2 0.1 0.1 4.4 0.3 0.1 0.2 0.0 0.4 1.8 SDC2 "CD362, fibroglycan, HSPG, HSPG1, SYND2" ENSG00000169439 "Syndecan 2" P34741 8 96493813-96611790 "CD markers, Predicted membrane proteins" "Differentiation, Neurogenesis" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 460.8;thyroid gland: 424.5" "Cell type enhanced" "Detected in many" "Fibroblasts: 229.7;Hepatocytes: 235.5;Smooth muscle cells: 183.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 7 "neutrophil: 13.6" "Lineage enriched" "Detected in many" 7 "granulocytes: 13.6" "Cell line enhanced" "Detected in many" "AF22: 643.1;EFO-21: 297.8;fHDF/TERT166: 288.4;RPTEC TERT1: 341.3;U-138 MG: 305.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB025123, HPA044416" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 85: Liver - Metabolism" "Cluster 12: NES - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane, Cytosol" "CAB025123: , HPA044416: AB_2678934" "unprognostic (1.25e-1)" "unprognostic (1.04e-1)" "unprognostic (1.25e-1)" "unprognostic (3.61e-2)" "unprognostic (6.52e-3)" "unprognostic (4.18e-2)" "unprognostic (2.43e-1)" "unprognostic (2.35e-2)" "unprognostic (2.89e-2)" "unprognostic (4.56e-1)" "unprognostic (1.48e-1)" "unprognostic (6.16e-2)" "unprognostic (1.56e-2)" "unprognostic (1.45e-3)" "unprognostic (1.91e-1)" "unprognostic (2.50e-2)" "unprognostic (1.23e-1)" 109.5 36.3 35.2 35.9 41.0 10.2 66.6 37.6 49.9 157.0 26.4 77.9 21.8 76.0 15.2 50.1 84.6 44.5 68.9 32.1 51.8 88.9 460.8 56.8 18.9 41.1 46.6 170.5 61.2 30.2 61.5 124.4 37.5 63.4 40.1 29.7 25.0 104.4 19.9 25.3 39.8 90.9 38.5 25.8 41.9 25.5 49.6 5.3 424.5 58.5 8.0 84.0 58.1 33.7 0.5 0.3 643.1 0.3 230.2 214.1 0.6 94.8 113.4 54.3 60.5 19.8 0.2 0.2 297.8 288.4 8.0 0.5 114.3 1.8 47.1 0.3 44.4 0.6 56.7 250.2 7.4 1.9 2.9 83.1 2.8 123.5 3.1 210.2 1.9 0.1 64.3 0.3 23.1 6.0 0.3 16.9 68.1 0.0 0.7 0.7 101.5 2.4 341.3 57.2 19.1 49.5 0.2 0.3 4.9 217.8 27.6 73.0 51.3 305.1 91.5 1.5 53.2 6.0 0.3 1.1 96.9 0.4 97.5 0.0 2.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.2 0.0 13.6 0.0 0.1 0.0 0.0 0.6 35.2 41.0 37.6 49.9 32.1 51.8 41.1 46.6 37.5 38.5 49.6 33.7 11.9 57.7 38.1 93.7 1.7 53.8 78.9 29.6 15.9 36.6 41.4 30.2 32.7 37.1 5.1 57.0 12.5 1.9 0.5 0.1 29.4 14.4 31.6 29.3 65.1 10.7 3.5 10.7 4.6 15.3 2.5 229.7 9.7 76.4 1.3 44.3 17.5 235.5 109.8 5.0 22.0 1.5 138.4 20.5 154.7 18.6 52.5 62.9 62.2 21.5 68.2 17.4 0.0 7.1 1.7 8.9 1.2 104.9 2.5 41.7 0.8 56.4 4.0 12.5 32.9 100.0 183.1 5.5 57.6 1.3 39.2 3.8 4.2 33.3 5.7 17.6 SDC4 "amphiglycan, ryudocan, SYND4" ENSG00000124145 "Syndecan 4" P31431 20 45325288-45348424 "Cancer-related genes, Predicted membrane proteins, Predicted secreted proteins, Transporters" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 410.9" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 515.9;Pancreatic endocrine cells: 476.4;Suprabasal keratinocytes: 472.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HBEC3-KT: 512.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005716, CAB013240" Enhanced Approved "Golgi apparatus,Plasma membrane" "Secreted to blood" NA NA 320000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 15: Liver - Metabolism" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 1: Pancreatic cells - Digestion" "Golgi apparatus" "Plasma membrane" "CAB013240: AB_2533250, HPA005716: AB_1080160" "unprognostic (1.34e-2)" "unprognostic (1.80e-1)" "unprognostic (1.71e-2)" "unprognostic (2.16e-1)" "unprognostic (5.39e-2)" "unprognostic (6.59e-3)" "unprognostic (1.16e-1)" "unprognostic (5.93e-2)" "unprognostic (2.68e-1)" "unprognostic (2.95e-2)" "prognostic unfavorable (4.20e-4)" "unprognostic (1.97e-1)" "prognostic favorable (2.44e-7)" "unprognostic (3.00e-1)" "unprognostic (2.18e-1)" "prognostic favorable (2.67e-4)" "unprognostic (7.42e-2)" 68.0 73.1 90.3 26.3 116.8 10.1 113.1 90.2 120.7 53.0 68.5 102.6 37.8 53.0 11.8 124.3 76.6 72.2 65.9 66.4 90.2 166.9 410.9 168.3 9.8 120.5 127.8 26.3 90.3 34.7 43.2 27.3 95.4 53.0 62.6 35.1 103.7 45.9 101.5 190.4 42.4 53.8 89.9 32.3 140.1 47.1 151.9 8.2 51.1 35.4 35.2 124.7 68.7 71.4 162.1 20.7 11.1 0.8 269.2 164.3 474.4 201.5 273.0 222.9 158.6 242.7 400.0 0.2 88.1 255.4 224.5 203.1 8.2 512.2 269.0 46.7 7.4 4.9 15.8 95.8 292.4 1.0 8.2 223.1 336.5 92.4 223.2 123.3 29.9 3.7 8.2 0.5 130.5 159.9 0.2 14.2 20.4 139.9 63.1 0.3 99.7 0.6 367.7 211.7 4.3 15.6 277.2 169.4 51.4 125.2 123.1 9.7 56.4 169.4 141.4 17.3 131.8 8.5 6.7 0.7 266.2 16.4 103.2 1.5 1.6 0.4 0.7 0.6 2.1 0.3 2.0 0.8 1.5 0.3 0.4 0.5 0.8 0.7 0.6 1.4 4.4 0.7 90.3 116.8 90.2 120.7 66.4 90.2 120.5 127.8 95.4 89.9 151.9 71.4 21.9 291.7 391.2 106.7 3.8 373.7 322.2 352.8 75.1 14.5 208.8 90.6 59.3 245.9 218.4 189.4 12.5 38.9 7.8 174.3 64.6 296.0 1.2 116.6 20.8 16.0 55.1 7.4 0.2 515.9 230.0 43.0 170.7 179.0 13.9 10.8 11.4 260.6 18.8 0.0 0.3 131.9 160.7 19.3 106.0 3.8 4.1 39.5 76.5 5.6 33.0 10.0 0.0 3.5 1.8 476.4 121.7 5.3 2.1 284.2 59.0 153.8 178.6 23.6 0.0 34.9 33.5 1.8 2.5 170.9 472.8 67.5 16.8 3.2 90.7 423.9 SEMA3D "coll-2, Sema-Z2" ENSG00000153993 "Semaphorin 3D" O95025 7 84995553-85186855 "Predicted intracellular proteins, Predicted secreted proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "lymphoid tissue: 47.8;thyroid gland: 45.4" "Cell type enhanced" "Detected in many" "Early spermatids: 157.4;Leydig cells: 52.5;Peritubular cells: 62.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 28.4;HaCaT: 28.7;TIME: 44.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037522 Uncertain Approved "Golgi apparatus,Plasma membrane" "Secreted in other tissues" NA NA 120000 "Cluster 64: Macrophages - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 29: Early spermatids - Spermatogenesis" "Golgi apparatus" "Plasma membrane" "HPA037522: AB_10672494" "unprognostic (7.05e-2)" "unprognostic (1.24e-1)" "unprognostic (2.40e-1)" "unprognostic (1.44e-2)" "unprognostic (1.54e-1)" "unprognostic (2.51e-1)" "unprognostic (7.58e-3)" "unprognostic (4.02e-3)" "unprognostic (9.94e-2)" "unprognostic (5.62e-2)" "unprognostic (1.63e-1)" "unprognostic (9.46e-2)" "unprognostic (1.17e-2)" "unprognostic (1.26e-3)" "unprognostic (1.63e-1)" "unprognostic (2.75e-3)" "unprognostic (5.25e-3)" 3.2 2.9 5.9 1.0 1.9 0.0 5.9 0.8 4.6 5.6 0.0 2.8 1.8 2.4 2.6 1.7 5.1 1.7 2.2 6.2 4.7 3.8 1.0 3.6 3.3 2.3 8.9 1.9 0.7 0.2 0.5 0.7 2.2 8.3 3.4 2.2 4.3 1.9 0.0 2.4 3.3 1.4 3.0 47.8 3.3 3.8 3.2 0.3 45.4 0.9 1.4 3.1 0.7 3.2 0.0 0.0 12.1 0.0 0.0 0.0 0.5 7.6 8.2 8.8 4.2 0.0 0.0 0.0 2.2 28.4 0.2 28.7 3.1 0.0 5.8 0.0 5.8 0.0 3.1 0.0 0.1 0.0 0.0 0.1 0.0 1.5 7.2 10.1 13.8 0.0 0.0 0.1 0.0 0.0 0.0 0.0 1.3 0.6 7.5 2.1 8.9 6.8 2.8 0.0 0.1 1.1 0.0 0.0 0.4 13.8 0.4 0.0 44.2 0.0 2.7 0.4 0.0 5.4 3.4 0.0 0.2 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.9 1.9 0.8 4.6 6.2 4.7 2.3 8.9 2.2 3.0 3.2 3.2 2.8 0.0 3.3 18.3 1.8 3.6 2.4 0.1 0.0 2.6 0.8 8.3 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 157.4 1.6 0.3 14.8 26.5 0.0 12.3 0.2 0.0 15.3 0.0 4.3 2.5 0.2 2.9 0.0 1.3 1.7 5.1 0.7 2.0 0.0 5.7 23.3 52.5 0.5 12.4 19.7 0.0 1.9 0.0 3.0 0.9 0.0 0.0 62.4 0.0 5.8 1.9 4.7 0.8 4.1 0.0 0.7 2.0 0.7 0.8 0.1 2.4 0.0 0.5 11.2 1.0 0.4 SEMA6D "FLJ11598, KIAA1479" ENSG00000137872 "Semaphorin 6D" Q8NFY4 15 47184101-47774228 "Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Differentiation, Neurogenesis" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 38.5;placenta: 43.1" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 114.7;Excitatory neurons: 120.7;Horizontal cells: 79.1;Inhibitory neurons: 319.5;Oligodendrocytes: 140.1" "Cancer enriched" "Detected in many" 4 "glioma: 8.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BJ hTERT+: 14.9;SCLC-21H: 13.3;SH-SY5Y: 12.1;SuSa: 14.2;U-266/70: 10.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA043109 Approved "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA 1100000 "Cluster 45: Intestine - Brush border" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" "Golgi apparatus" "HPA043109: AB_10793941" "unprognostic (2.00e-1)" "unprognostic (4.62e-2)" "unprognostic (3.10e-2)" "unprognostic (3.83e-3)" "unprognostic (1.38e-1)" "unprognostic (3.85e-2)" "unprognostic (1.98e-1)" "unprognostic (2.17e-3)" "unprognostic (1.24e-1)" "unprognostic (5.36e-2)" "unprognostic (7.96e-4)" "unprognostic (1.42e-1)" "prognostic favorable (5.96e-5)" "unprognostic (3.74e-2)" "unprognostic (8.56e-2)" "unprognostic (3.30e-3)" "unprognostic (2.39e-4)" 5.5 1.5 11.3 3.9 27.9 0.4 5.0 11.1 21.3 5.8 0.0 10.6 21.8 1.6 2.5 1.7 4.9 4.0 9.4 9.8 16.3 15.1 3.1 8.9 2.1 17.2 31.1 26.7 16.1 10.6 5.5 43.1 23.1 4.5 12.7 15.8 4.5 8.4 20.9 3.0 38.5 3.3 12.0 2.5 3.0 2.6 20.5 2.7 5.8 6.0 0.6 3.1 10.0 28.8 0.0 0.0 2.5 0.0 1.5 1.2 0.2 0.6 14.9 0.4 0.0 0.3 0.1 2.2 0.0 4.0 0.0 7.6 3.4 1.1 0.1 1.1 1.7 0.0 5.0 0.0 4.0 0.0 0.2 1.1 8.3 0.0 0.5 0.0 1.0 5.7 0.1 3.4 0.4 0.8 2.8 0.7 4.6 0.0 0.0 1.6 0.1 2.4 1.1 1.1 13.3 12.1 0.1 1.0 4.3 14.2 0.5 0.0 0.0 6.9 0.3 0.2 0.0 10.0 0.0 2.3 1.8 0.3 1.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 11.3 27.9 11.1 21.3 9.8 16.3 17.2 31.1 23.1 12.0 20.5 28.8 13.9 51.3 1.5 72.8 0.2 2.0 4.0 1.4 1.2 6.2 0.5 10.7 10.0 4.3 2.1 11.0 114.7 19.7 0.1 40.6 5.9 1.0 0.2 0.5 2.3 10.1 17.4 0.0 120.7 0.2 1.8 10.8 0.0 0.3 3.8 71.0 5.0 0.9 2.6 79.1 319.5 5.4 0.0 0.0 1.9 1.2 23.3 1.0 8.8 15.9 0.0 9.3 0.0 43.2 140.1 0.3 8.5 13.5 0.0 1.2 53.5 0.2 0.1 2.3 0.0 9.3 13.9 0.8 6.3 0.3 1.1 4.7 0.2 3.4 15.1 1.6 SERINC2 "FKSG84, PRO0899, TDE2, TDE2L" ENSG00000168528 "Serine incorporator 2" Q96SA4 1 31409565-31434680 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 235.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 466.3;Distal enterocytes: 530.1;Ductal cells: 735.4;Pancreatic endocrine cells: 457.4;Paneth cells: 465.1;Proximal enterocytes: 422.0;Syncytiotrophoblasts: 446.6;Urothelial cells: 432.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 4 "plasmacytoid DC: 10.4" "Lineage enriched" "Detected in many" 4 "dendritic cells: 10.4" "Cell line enhanced" "Detected in many" "CAPAN-2: 305.6;HaCaT: 349.2;HBEC3-KT: 553.0;hTCEpi: 307.8;RT4: 381.9;SK-BR-3: 311.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA005974 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA005974: AB_10603239" "unprognostic (1.41e-1)" "unprognostic (3.70e-3)" "unprognostic (8.78e-3)" "prognostic favorable (1.69e-7)" "unprognostic (6.78e-2)" "unprognostic (5.31e-2)" "prognostic unfavorable (2.11e-4)" "prognostic unfavorable (5.70e-4)" "unprognostic (3.12e-2)" "unprognostic (3.19e-2)" "unprognostic (1.11e-2)" "unprognostic (1.09e-2)" "unprognostic (3.74e-2)" "unprognostic (1.39e-1)" "unprognostic (2.48e-1)" "unprognostic (4.63e-3)" "unprognostic (2.67e-2)" 6.5 23.8 1.2 15.0 1.4 8.1 33.8 1.5 1.2 68.9 2.9 111.0 118.7 15.3 21.4 120.7 18.9 59.1 3.2 1.0 1.7 114.1 235.5 20.9 3.5 1.8 2.2 0.9 37.7 45.8 9.7 44.5 1.9 56.6 56.2 0.1 151.0 62.1 76.8 53.5 105.6 2.6 1.6 3.4 90.7 4.9 5.8 8.8 28.4 24.5 9.5 116.5 39.3 1.8 87.3 20.5 17.7 57.0 37.3 50.4 48.2 162.8 119.5 10.6 13.1 31.1 305.6 57.0 209.5 154.6 12.9 349.2 2.3 553.0 2.1 5.5 13.2 0.0 17.2 16.6 42.0 0.5 64.1 46.0 307.8 66.5 144.2 45.5 6.7 6.9 2.6 0.5 18.2 14.2 2.1 2.0 18.3 172.1 42.4 0.4 34.8 19.5 57.9 381.9 7.6 42.4 41.7 311.0 6.5 8.5 182.8 9.9 40.7 2.8 13.0 1.8 3.4 2.9 2.1 2.6 1.4 1.6 13.7 0.0 2.4 2.2 0.0 0.7 0.0 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.1 10.4 0.0 0.6 1.2 1.4 1.5 1.2 1.0 1.7 1.8 2.2 1.9 1.6 5.8 1.8 2.2 16.0 8.9 0.0 2.7 12.4 108.7 374.7 37.0 0.0 162.9 72.9 0.7 138.7 173.3 117.7 0.0 466.3 4.2 530.1 72.4 735.4 6.4 61.6 18.2 8.8 116.6 3.6 0.4 326.3 91.2 5.4 80.0 140.7 0.0 1.6 5.7 54.5 47.5 0.0 0.4 195.0 183.1 5.1 5.0 12.9 2.1 13.1 40.9 1.0 48.4 0.6 0.0 0.0 0.2 457.4 465.1 0.0 0.1 192.2 422.0 71.0 54.3 0.0 0.0 23.5 19.3 0.7 9.5 30.8 21.2 446.6 3.5 0.1 145.7 432.5 SERPINB3 "HsT1196, SCC, SCCA1, T4-A" ENSG00000057149 "Serpin family B member 3" P29508 18 63655197-63661893 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" "Protease inhibitor, Serine protease inhibitor" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "cervix: 418.5;esophagus: 809.7;vagina: 669.6" "Group enriched" "Detected in some" 6 "Basal respiratory cells: 6903.4;Club cells: 6726.1" "Group enriched" "Detected in many" 4 "cervical cancer: 186.5;head and neck cancer: 69.3" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "CAPAN-2: 1.9;HaCaT: 6.5;HBEC3-KT: 1.6;SiHa: 4.1;U-2197: 8.2" "CAB018772, CAB036006, CAB036007, HPA048341, HPA049988, HPA055992" Enhanced Approved "Plasma membrane,Cytosol" NA NA 9100000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 18: U-2197 - ECM organization" "Cluster 26: Respiratory epithelial cells - Mucosal defense" Cytosol "Plasma membrane" "CAB018772: AB_2285759, CAB036006: , CAB036007: , HPA048341: AB_2680364, HPA049988: AB_2680985, HPA055992: AB_2682998" "unprognostic (2.95e-3)" "unprognostic (1.66e-1)" "unprognostic (2.03e-1)" "unprognostic (2.91e-2)" "unprognostic (2.11e-1)" "prognostic unfavorable (3.19e-4)" "unprognostic (6.68e-2)" "unprognostic (2.58e-1)" "unprognostic (4.19e-3)" 0.1 0.1 0.0 0.3 0.0 0.0 1.1 0.0 0.0 418.5 0.0 0.1 0.0 3.2 0.0 809.7 0.2 0.2 0.4 0.0 0.0 0.1 0.2 3.1 0.0 0.0 0.0 0.1 0.2 0.0 0.9 0.0 0.0 7.6 0.0 0.0 100.0 0.0 0.1 42.9 0.1 0.0 0.0 0.1 0.5 1.9 0.0 4.8 0.1 0.0 19.6 73.8 669.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 1.9 0.0 0.0 0.1 0.1 6.5 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 1.4 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 8.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.1 0.0 0.0 0.0 35.2 6903.4 2.2 0.0 0.0 0.0 0.0 0.0 6726.1 0.0 0.0 0.0 0.0 0.0 0.0 6.2 31.4 0.1 0.2 0.5 0.0 0.0 0.0 8.9 0.0 3.0 0.0 0.9 2.5 0.0 0.0 0.0 0.1 0.0 0.0 0.0 986.7 0.0 0.0 55.4 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.8 0.0 0.4 0.0 60.2 0.0 0.2 447.6 0.0 0.0 0.0 178.1 1.0 0.3 413.5 0.0 0.3 0.8 0.0 0.0 265.9 SH3BGR 21-GARP ENSG00000185437 "SH3 domain binding glutamate rich protein" P55822 21 39445855-39515506 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in all" 6 "skeletal muscle: 1268.3;tongue: 578.1" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 180.2;Distal tubular cells: 46.9;Early spermatids: 151.2" "Cancer enhanced" "Detected in all" "glioma: 21.8" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 3.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "U-87 MG: 101.0" "Low region specificity" "Detected in all" CAB003685 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "CAB003685: AB_425682" "unprognostic (3.41e-2)" "unprognostic (1.26e-1)" "unprognostic (5.84e-3)" "unprognostic (1.68e-3)" "unprognostic (6.05e-2)" "unprognostic (6.12e-3)" "unprognostic (3.89e-2)" "unprognostic (9.78e-2)" "unprognostic (2.06e-1)" "unprognostic (6.97e-3)" "unprognostic (3.59e-2)" "unprognostic (4.75e-1)" "unprognostic (5.98e-3)" "unprognostic (7.16e-2)" "unprognostic (4.60e-2)" "unprognostic (1.68e-2)" "unprognostic (2.06e-2)" 8.9 24.0 41.8 3.6 44.9 2.0 11.2 42.0 72.4 10.8 37.3 39.4 6.6 12.3 28.5 20.3 8.1 9.5 154.1 43.7 43.0 13.2 11.8 5.4 2.0 43.8 40.8 6.0 11.0 10.7 25.6 2.1 44.4 25.1 7.0 14.7 14.2 21.2 1268.3 4.8 8.5 11.0 41.0 3.3 16.9 20.1 42.4 3.2 16.3 578.1 2.1 20.8 8.1 50.5 2.0 2.9 3.7 4.2 5.5 9.2 1.0 2.7 0.6 1.9 1.5 1.6 3.9 6.6 8.9 10.9 14.5 0.3 1.2 3.1 2.9 3.9 7.6 7.6 0.9 3.1 15.1 2.8 1.3 7.6 13.5 7.0 12.1 3.4 1.8 13.9 5.0 7.7 7.8 9.4 3.7 4.2 3.2 6.2 6.2 6.5 13.1 4.5 8.3 1.8 10.0 4.0 5.8 4.9 5.4 2.3 19.8 0.5 1.6 5.0 0.6 3.1 7.9 26.3 5.7 6.7 101.0 5.0 6.9 0.0 0.2 0.0 0.2 0.9 0.9 1.4 0.4 0.9 0.9 0.6 1.6 1.2 0.2 1.2 0.9 3.7 0.1 0.4 41.8 44.9 42.0 72.4 43.7 43.0 43.8 40.8 44.4 41.0 42.4 50.5 2.4 3.2 3.9 15.3 1.4 2.7 12.8 5.9 1.8 2.1 11.4 25.0 180.2 5.7 4.4 5.5 4.2 3.7 3.2 2.3 46.9 5.1 151.2 11.3 5.0 3.1 1.2 0.8 6.4 21.3 1.7 5.6 3.6 10.6 4.5 5.3 2.2 9.2 2.4 5.0 6.5 1.7 4.1 1.6 2.0 35.4 2.1 1.5 12.4 5.6 1.2 21.2 0.0 3.0 14.6 4.8 3.2 5.7 1.0 3.3 2.3 14.4 6.7 6.2 6.6 22.7 16.9 32.4 23.6 1.1 1.7 1.9 1.4 4.7 2.7 4.6 SH3D21 "C1orf113, FLJ22938" ENSG00000214193 "SH3 domain containing 21" A4FU49 1 36306368-36329340 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 20.9;thyroid gland: 27.8" "Cell type enhanced" "Detected in many" "Distal enterocytes: 15.3;Late spermatids: 53.6;Proximal enterocytes: 14.9" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 6.8" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 14.4;HaCaT: 21.1;hTERT-RPE1: 21.7" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA042212, HPA042456, HPA066168" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 7: Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 25: Spermatids - Spermatogenesis" Nucleoplasm "Plasma membrane" "HPA042212: AB_10961180, HPA042456: AB_10959746, HPA066168: AB_2685627" "prognostic favorable (2.60e-4)" "unprognostic (8.35e-3)" "unprognostic (3.86e-3)" "unprognostic (9.01e-2)" "unprognostic (2.07e-3)" "unprognostic (7.32e-3)" "unprognostic (2.04e-4)" "unprognostic (7.47e-2)" "unprognostic (3.47e-2)" "unprognostic (1.01e-1)" "unprognostic (2.43e-2)" "unprognostic (7.38e-3)" "prognostic unfavorable (1.76e-6)" "unprognostic (8.88e-2)" "unprognostic (2.25e-1)" "unprognostic (7.99e-2)" "unprognostic (8.59e-2)" 1.1 0.7 2.4 2.5 1.1 1.3 10.8 0.2 6.8 4.4 0.0 3.4 14.0 2.2 1.4 6.9 1.2 2.0 2.0 0.8 0.0 8.8 0.8 3.9 2.0 1.1 0.2 3.5 0.5 0.3 1.7 3.1 1.0 6.7 3.7 3.2 13.4 1.4 0.8 17.4 20.9 1.1 0.0 2.2 2.0 6.8 0.8 0.7 27.8 0.3 3.0 1.3 7.2 0.2 11.2 0.3 2.0 2.2 0.5 1.3 14.4 6.1 0.9 2.8 1.3 7.1 4.3 2.2 5.5 1.6 0.3 21.1 1.4 3.3 2.1 0.9 2.1 2.1 4.8 5.3 1.1 1.2 3.2 0.9 3.0 1.9 1.4 21.7 1.0 4.3 0.4 2.6 1.6 7.3 1.4 1.1 1.2 2.6 2.4 2.3 0.3 1.2 3.7 1.8 4.4 2.1 1.1 11.0 3.4 10.3 0.7 0.3 3.2 1.6 1.2 4.3 1.0 3.3 1.0 2.2 3.9 1.3 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.0 0.0 2.4 1.1 0.2 6.8 0.8 0.0 1.1 0.2 1.0 0.0 0.8 0.2 1.1 0.0 2.0 0.3 1.7 3.1 1.7 3.0 1.8 6.9 6.2 4.3 1.4 0.0 1.9 5.5 0.0 2.9 1.9 15.3 1.9 0.6 14.2 2.5 2.0 1.6 0.0 0.0 1.6 0.4 2.2 1.9 4.6 7.7 1.3 2.6 1.1 0.3 7.7 11.8 1.2 2.9 2.0 6.1 7.7 53.6 1.2 5.0 3.6 0.0 2.2 1.2 1.0 0.0 0.2 4.3 5.8 2.6 2.9 2.6 14.9 1.1 2.3 1.2 0.0 0.7 2.1 2.6 1.2 2.4 3.1 5.7 1.3 3.2 1.6 1.3 SHANK3 "KIAA1650, prosap2, PSAP2, SPANK-2" ENSG00000251322 "SH3 and multiple ankyrin repeat domains 3" 22 50674415-50733298 "Human disease related genes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 73.5" "Cell type enhanced" "Detected in many" "Adipocytes: 195.3;Endothelial cells: 65.0;Hepatic stellate cells: 70.3;Microglial cells: 44.0;Oligodendrocytes: 31.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 33.3;TIME: 37.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003446 Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA003446: AB_1079958" "unprognostic (3.62e-1)" "unprognostic (1.08e-2)" "prognostic unfavorable (7.40e-4)" "unprognostic (6.02e-2)" "unprognostic (4.17e-1)" "unprognostic (1.72e-3)" "unprognostic (3.41e-2)" "unprognostic (3.13e-1)" "unprognostic (9.67e-2)" "unprognostic (5.62e-2)" "unprognostic (2.09e-2)" "unprognostic (7.52e-2)" "unprognostic (2.47e-2)" "unprognostic (7.81e-2)" "unprognostic (1.19e-1)" "unprognostic (4.89e-2)" "unprognostic (1.41e-1)" 34.9 4.0 38.9 4.9 21.6 1.1 33.5 73.5 54.7 12.8 0.0 7.5 3.4 13.4 2.0 5.2 12.4 5.8 26.2 44.7 14.9 11.9 4.4 20.3 4.2 10.0 15.3 4.3 4.0 3.5 5.2 13.7 2.6 8.3 1.2 0.7 8.2 4.2 23.3 7.1 6.4 5.1 0.0 50.4 5.7 2.2 38.6 1.7 14.8 8.9 1.4 10.7 10.1 16.2 6.6 2.6 6.2 4.8 0.5 1.6 3.2 1.3 0.0 0.4 0.5 1.6 2.4 0.0 4.0 1.0 3.1 1.2 0.9 2.3 0.0 0.0 10.4 8.0 1.8 7.1 1.9 1.8 0.4 2.2 1.8 0.1 0.3 0.1 33.3 1.9 0.2 0.2 0.5 2.6 1.4 0.5 3.2 0.6 2.2 7.5 0.0 1.7 0.4 1.3 2.3 3.0 2.7 0.0 3.1 0.7 0.3 0.7 37.6 0.4 9.3 2.0 0.7 0.3 0.4 0.0 0.0 0.6 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.9 21.6 73.5 54.7 44.7 14.9 10.0 15.3 2.6 0.0 38.6 16.2 195.3 0.0 1.1 4.6 0.5 0.3 0.1 0.5 4.0 1.2 1.3 2.4 27.6 0.0 0.8 0.0 0.0 0.0 0.8 0.1 0.0 0.0 2.9 3.9 2.4 65.0 2.4 0.0 28.3 0.0 0.0 3.3 0.0 1.5 0.0 0.3 70.3 6.5 0.4 0.0 21.7 0.0 2.0 3.1 0.0 0.4 0.0 0.3 0.0 44.0 0.0 1.4 0.0 25.1 31.3 0.1 0.0 0.4 0.0 0.2 0.0 0.9 0.9 0.0 0.0 1.0 3.8 0.2 0.8 1.0 0.3 0.0 0.6 0.7 0.1 0.3 SHISA6 FLJ45455 ENSG00000188803 "Shisa family member 6" Q6ZSJ9 17 11241213-11564063 "Predicted membrane proteins, Transporters" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 4 "brain: 46.2;cervix: 16.8" "Cell type enhanced" "Detected in some" "Astrocytes: 50.3;Excitatory neurons: 27.4;Inhibitory neurons: 181.4;Oligodendrocyte precursor cells: 77.4;Peritubular cells: 29.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 23 "OE19: 52.0" "Low region specificity" "Detected in all" HPA023440 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 70: Brain - Nervous system development" "Cluster 21: OE19 - Mitochondria" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA023440: AB_1848945" "unprognostic (1.70e-1)" "unprognostic (2.78e-2)" "unprognostic (1.44e-1)" "unprognostic (2.39e-3)" "prognostic unfavorable (8.41e-4)" "unprognostic (3.11e-2)" "unprognostic (1.71e-1)" "unprognostic (8.80e-2)" "unprognostic (1.84e-1)" "unprognostic (1.11e-1)" "unprognostic (9.63e-2)" "unprognostic (1.27e-1)" "unprognostic (2.40e-4)" "unprognostic (1.14e-1)" "unprognostic (1.32e-1)" "unprognostic (4.20e-2)" "unprognostic (2.47e-2)" 1.7 0.6 17.7 0.0 11.0 0.0 1.1 23.2 25.3 16.8 0.8 0.6 0.2 6.2 0.7 0.8 1.8 0.3 0.8 46.2 18.9 1.9 0.0 0.2 0.0 43.3 25.5 0.6 1.0 3.4 0.2 0.1 24.4 4.3 0.4 1.1 0.2 7.3 0.7 0.8 0.3 0.5 44.8 0.0 4.2 2.9 34.7 0.0 0.5 1.3 0.0 1.1 3.4 27.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 52.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 17.7 11.0 23.2 25.3 46.2 18.9 43.3 25.5 24.4 44.8 34.7 27.0 0.9 0.0 0.0 50.3 0.0 0.1 0.1 0.0 1.2 4.0 1.8 0.9 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.5 16.9 1.6 1.2 0.0 27.4 0.0 0.0 2.1 0.0 0.5 0.0 5.6 0.4 0.0 0.1 0.0 181.4 0.0 0.0 0.0 0.3 15.2 5.0 0.0 1.8 12.2 0.0 0.8 0.0 77.4 2.4 0.0 0.0 29.0 0.0 0.8 0.0 0.2 0.0 0.2 0.0 0.2 1.7 0.4 2.5 0.1 0.1 0.0 0.1 4.4 0.2 0.2 SIGLEC14 ENSG00000254415 "Sialic acid binding Ig like lectin 14" Q08ET2 19 51642553-51646801 "Plasma proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "bone marrow: 28.3;lymphoid tissue: 40.3" "Cell type enhanced" "Detected in some" "Hofbauer cells: 18.5;Kupffer cells: 41.5;Macrophages: 13.5;monocytes: 24.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 6 "classical monocyte: 109.1;intermediate monocyte: 125.1;myeloid DC: 65.4;neutrophil: 200.1;non-classical monocyte: 93.3" "Group enriched" "Detected in many" 7 "dendritic cells: 65.4;granulocytes: 200.1;monocytes: 125.1" "Group enriched" "Detected in some" 11 "HMC-1: 98.7;U-937: 24.7" "HPA014377, HPA014428" Uncertain Uncertain "Vesicles,Plasma membrane" NA NA 24000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" Vesicles "Plasma membrane" "HPA014377: AB_2189277, HPA014428: " "unprognostic (3.05e-1)" "unprognostic (1.75e-1)" "unprognostic (6.47e-3)" "unprognostic (1.60e-1)" "unprognostic (3.83e-2)" "unprognostic (1.50e-2)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (9.77e-3)" "unprognostic (9.28e-2)" "unprognostic (6.73e-2)" "unprognostic (1.02e-1)" "unprognostic (4.28e-3)" "unprognostic (8.38e-2)" "unprognostic (4.17e-2)" "unprognostic (1.34e-1)" "unprognostic (1.89e-1)" 3.4 2.4 1.4 25.2 1.5 28.3 1.0 1.6 3.2 1.8 1.3 1.8 0.7 0.9 0.3 1.1 2.3 2.6 1.3 1.4 2.4 0.7 3.5 7.3 13.3 4.7 3.0 0.4 1.1 0.4 0.5 2.5 3.9 0.9 1.6 0.1 1.1 0.9 0.4 0.3 6.1 2.5 2.7 40.3 1.6 2.4 3.9 1.9 0.6 0.0 14.2 4.1 0.6 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 5.8 0.0 0.0 0.0 1.6 98.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 4.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 24.7 0.0 16.6 109.1 1.8 0.3 125.1 0.1 19.3 0.2 0.3 65.4 18.2 0.1 0.1 200.1 0.7 93.3 12.0 0.2 40.3 1.4 1.5 1.6 3.2 1.4 2.4 4.7 3.0 3.9 2.7 3.9 4.1 0.0 0.0 1.1 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.5 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.2 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.2 0.4 0.0 0.0 0.0 0.0 0.0 0.4 18.5 0.0 0.0 0.0 0.0 41.5 6.0 0.8 0.3 13.5 0.0 1.0 24.1 0.0 2.1 0.0 0.0 0.0 0.0 2.6 0.1 0.0 0.0 0.0 0.7 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.3 0.7 0.0 0.0 0.0 SIGLEC6 "CD327, CD33L, CD33L1, OB-BP1, SIGLEC-6" ENSG00000105492 "Sialic acid binding Ig like lectin 6" O43699 19 51517819-51531856 "CD markers, Predicted membrane proteins, Predicted secreted proteins" "Cell adhesion" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 24 "placenta: 106.7" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 76.0;granulocytes: 55.0;Syncytiotrophoblasts: 188.7" "Cancer enhanced" "Detected in some" "thyroid cancer: 2.7" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "basophil: 4.9;memory B-cell: 7.2;naive B-cell: 4.5;plasmacytoid DC: 11.0" "Group enriched" "Detected in many" 13 "B-cells: 7.2;dendritic cells: 11.0;granulocytes: 4.9" "Cell line enriched" "Detected in some" 7 "HMC-1: 500.7" "HPA008945, HPA009084, HPA018198" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to blood" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 28: Placenta - Pregnancy" "Cluster 3: HMC-1 - Innate immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane, Cytosol" "HPA008945: , HPA009084: AB_1079967, HPA018198: AB_1856868" "unprognostic (1.97e-1)" "unprognostic (1.41e-1)" "unprognostic (2.38e-3)" "unprognostic (9.31e-3)" "unprognostic (8.46e-4)" "unprognostic (2.91e-1)" "unprognostic (2.02e-2)" "unprognostic (2.64e-1)" "unprognostic (8.96e-2)" "unprognostic (2.03e-1)" "unprognostic (6.89e-2)" "unprognostic (1.10e-2)" "unprognostic (4.15e-2)" "unprognostic (4.42e-2)" "unprognostic (3.28e-2)" "unprognostic (5.57e-3)" 0.6 0.1 0.2 3.0 0.3 0.5 0.7 0.4 0.3 1.6 0.1 2.2 2.2 1.5 1.0 2.5 0.3 2.5 0.4 0.2 0.0 0.1 0.1 4.3 3.8 0.1 0.1 0.1 0.3 0.1 0.0 106.7 0.2 1.0 3.1 0.4 0.5 0.7 0.5 0.5 3.3 1.3 0.0 1.7 2.6 0.3 0.2 0.7 0.0 0.6 4.2 1.8 0.4 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 15.8 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 73.1 0.0 0.0 0.0 1.2 500.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.7 0.0 0.0 0.3 3.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 19.1 0.0 1.5 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.9 0.2 4.9 0.1 0.0 0.0 0.0 0.0 7.2 0.0 0.0 1.6 4.5 0.0 0.0 0.2 0.6 0.0 11.0 0.0 0.4 0.2 0.3 0.4 0.3 0.2 0.0 0.1 0.1 0.2 0.0 0.2 0.5 0.0 0.0 1.1 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 76.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 0.0 5.2 0.7 0.0 0.0 55.0 0.0 0.0 0.0 8.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 188.7 0.5 0.0 0.0 0.0 SIGLEC7 "CD328, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2" ENSG00000168995 "Sialic acid binding Ig like lectin 7" Q9Y286 19 51142299-51153526 "CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Cell adhesion" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "lymphoid tissue: 19.2" "Cell type enhanced" "Detected in some" "Hofbauer cells: 31.3;Kupffer cells: 57.4;Macrophages: 33.1;monocytes: 15.5;NK-cells: 69.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "eosinophil: 242.1" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 9 "Karpas-707: 55.4;RPMI-8226: 33.7;U-937: 35.0" HPA075513 Approved "Vesicles,Plasma membrane" "Intracellular and membrane" NA NA 2600000 "Cluster 45: Eosinophils - Innate immune response" "Cluster 64: Macrophages - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane" Vesicles "HPA075513: " "unprognostic (3.14e-1)" "unprognostic (5.87e-2)" "unprognostic (1.03e-1)" "unprognostic (2.66e-1)" "unprognostic (3.90e-2)" "unprognostic (1.85e-1)" "unprognostic (2.53e-1)" "unprognostic (2.78e-1)" "unprognostic (1.69e-1)" "unprognostic (4.95e-2)" "unprognostic (1.10e-1)" "unprognostic (2.66e-1)" "unprognostic (8.27e-2)" "unprognostic (6.61e-2)" "unprognostic (1.14e-3)" "unprognostic (2.58e-1)" "unprognostic (2.26e-2)" 3.7 2.9 0.9 10.6 1.0 4.6 1.0 1.0 1.9 0.6 1.2 1.9 1.6 0.5 0.4 0.4 1.2 2.6 1.3 0.8 1.3 1.6 7.4 5.0 7.7 2.1 1.5 0.4 0.5 0.7 0.6 6.2 1.9 0.7 2.4 0.2 0.7 0.4 0.2 0.2 2.2 3.8 1.4 19.2 0.9 0.9 2.2 1.5 0.5 0.3 2.4 3.1 0.5 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.5 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 55.4 0.0 0.0 0.0 4.6 0.0 0.0 0.0 0.0 0.1 33.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 0.0 1.2 1.1 0.0 0.2 35.0 0.0 3.2 140.2 242.1 10.6 105.8 18.9 3.8 0.2 4.8 65.5 0.2 0.3 4.4 116.7 96.8 44.0 2.9 0.0 80.9 0.9 1.0 1.0 1.9 0.8 1.3 2.1 1.5 1.9 1.4 2.2 2.4 0.4 0.0 2.2 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 1.8 0.0 0.2 8.3 0.1 0.0 0.0 0.4 0.0 0.2 0.6 0.0 8.8 0.0 0.0 0.2 0.3 0.0 0.0 1.3 0.0 6.1 0.8 31.3 0.0 0.0 0.0 0.0 57.4 3.5 0.0 1.5 33.1 0.0 0.0 15.5 0.0 69.0 0.0 0.0 0.1 0.0 1.2 0.1 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 3.5 0.4 0.0 0.0 SIN3B KIAA0700 ENSG00000127511 "SIN3 transcription regulator family member B" O75182 19 16829398-16880353 "Metabolic proteins, Predicted intracellular proteins" "Transcription, Transcription regulation" Repressor "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Syncytiotrophoblasts: 124.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050329 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 71: Testis - DNA repair" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA050329: AB_2681089" "unprognostic (2.71e-3)" "unprognostic (8.89e-2)" "unprognostic (1.32e-3)" "unprognostic (6.22e-2)" "unprognostic (1.24e-1)" "unprognostic (2.05e-2)" "unprognostic (5.44e-2)" "unprognostic (9.89e-2)" "unprognostic (5.42e-3)" "unprognostic (2.77e-1)" "prognostic favorable (4.37e-4)" "prognostic unfavorable (3.58e-4)" "unprognostic (1.18e-3)" "unprognostic (8.45e-2)" "unprognostic (1.49e-1)" "unprognostic (9.36e-2)" "unprognostic (1.06e-1)" 38.6 31.7 30.1 21.7 28.4 12.6 42.0 8.6 33.3 57.2 12.7 35.9 15.0 59.3 24.1 25.9 49.9 20.4 27.3 30.1 22.7 31.6 19.8 43.6 26.8 19.8 21.8 58.0 25.5 37.8 32.3 29.0 27.0 43.9 12.3 10.0 30.9 35.2 24.7 32.9 36.4 30.6 10.3 43.0 27.2 51.7 24.8 13.2 42.8 14.9 18.1 34.0 43.7 24.5 28.1 14.7 24.4 31.5 19.7 18.1 76.8 23.3 19.2 31.6 27.9 36.4 25.7 25.0 25.5 27.2 26.7 23.6 20.4 20.9 29.1 26.2 36.8 27.0 35.6 16.7 25.9 15.8 20.8 29.9 26.9 21.3 18.2 25.1 29.1 19.7 22.2 15.0 22.4 33.7 21.7 25.5 30.4 14.6 46.6 28.4 22.4 16.6 18.0 23.5 18.0 22.5 29.6 22.5 18.4 32.5 15.9 14.7 38.6 30.5 18.5 44.6 26.5 21.3 16.8 25.0 21.1 20.6 23.1 0.1 4.2 3.9 1.0 3.8 0.6 3.5 0.9 1.1 1.3 2.7 1.1 0.8 2.0 1.2 3.4 1.5 0.3 1.5 30.1 28.4 8.6 33.3 30.1 22.7 19.8 21.8 27.0 10.3 24.8 24.5 45.4 22.4 11.9 30.7 18.9 7.9 11.6 7.4 14.2 20.3 14.4 18.4 8.3 1.5 8.6 3.7 14.6 21.9 9.5 7.0 3.9 10.6 11.4 16.3 34.6 18.8 4.9 6.9 29.9 8.6 29.2 16.0 13.7 36.2 5.1 29.9 10.8 7.0 17.6 10.1 29.8 8.4 0.0 14.6 5.5 24.2 50.7 13.9 5.4 19.7 14.6 8.0 10.3 21.6 26.3 14.5 4.0 66.5 22.0 14.2 4.2 7.5 6.9 14.5 6.6 17.5 13.7 9.7 9.2 14.4 8.1 124.9 11.7 34.5 7.3 17.9 SIPA1L1 "E6TP1, KIAA0440, SPAR1" ENSG00000197555 "Signal induced proliferation associated 1 like 1" O43166 14 71320449-71741229 "Predicted intracellular proteins" "GTPase activation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 575.1;Inhibitory neurons: 447.6;Oligodendrocyte precursor cells: 221.2;Oligodendrocytes: 251.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in many" "neutrophil: 22.9" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "U-138 MG: 101.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA002875, HPA077689" Approved Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 65: Brain - Ion transport" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" "Actin filaments" "HPA002875: AB_1079974, HPA077689: " "unprognostic (1.50e-3)" "unprognostic (2.99e-1)" "unprognostic (3.34e-2)" "unprognostic (5.64e-3)" "unprognostic (4.19e-2)" "unprognostic (4.14e-1)" "unprognostic (7.89e-2)" "unprognostic (4.86e-2)" "unprognostic (3.09e-1)" "unprognostic (8.62e-2)" "unprognostic (2.61e-1)" "unprognostic (5.27e-2)" "prognostic favorable (6.80e-8)" "unprognostic (1.02e-1)" "unprognostic (1.37e-1)" "unprognostic (1.42e-1)" "unprognostic (7.03e-2)" 6.2 14.5 29.7 11.6 33.4 11.7 9.0 6.1 27.8 9.4 31.3 12.1 10.3 7.1 11.0 14.4 13.8 15.5 3.3 30.9 4.5 14.9 12.3 11.5 11.0 2.7 0.5 4.7 12.7 19.2 16.0 5.1 1.4 7.9 11.7 13.3 10.7 8.5 3.0 8.7 11.1 10.5 0.6 25.3 18.1 19.8 10.1 12.5 14.3 2.8 15.8 12.7 6.1 11.3 27.0 8.3 18.9 14.2 5.6 16.0 34.2 35.9 42.4 14.3 18.1 48.1 14.8 12.6 9.1 59.1 12.9 26.1 13.9 32.3 27.1 11.4 6.5 26.5 55.3 11.3 46.3 3.2 9.8 11.7 26.7 22.1 52.0 16.3 15.5 17.5 11.8 30.7 19.8 40.5 10.8 3.0 10.8 24.6 22.4 15.7 20.4 13.4 10.2 41.1 23.2 61.9 36.8 28.6 2.6 12.1 17.0 1.4 43.3 101.4 37.2 11.6 20.8 25.0 30.3 18.3 17.3 8.6 34.6 6.9 5.2 1.1 1.7 5.8 3.8 3.2 1.5 2.4 1.3 7.4 1.0 1.1 22.9 2.2 7.1 0.4 1.6 2.3 29.7 33.4 6.1 27.8 30.9 4.5 2.7 0.5 1.4 0.6 10.1 11.3 14.4 67.3 30.5 163.9 53.8 11.9 15.2 20.2 30.7 19.6 13.0 21.2 5.3 21.5 23.6 14.7 18.8 7.8 23.9 19.3 13.7 24.6 74.4 28.8 18.8 12.9 32.4 1.3 575.1 19.9 8.5 11.3 46.9 35.3 13.9 26.4 5.0 17.5 5.1 58.9 447.6 16.8 10.2 21.4 67.2 31.2 7.8 49.2 5.4 120.9 34.6 58.2 9.2 221.2 251.3 23.0 15.5 35.3 24.9 16.2 18.3 28.4 34.4 15.9 0.0 5.4 18.2 22.4 36.8 17.3 8.4 9.4 24.3 102.0 22.5 27.2 SLAMF6 "CD352, KALI, KALIb, Ly108, NTB-A, NTBA, SF2000" ENSG00000162739 "SLAM family member 6" Q96DU3 1 160485030-160523262 "CD markers, Predicted membrane proteins" "Adaptive immunity, Immunity, Innate immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 4 "lymphoid tissue: 61.7" "Cell type enhanced" "Detected in some" "B-cells: 23.6;dendritic cells: 19.7;Late spermatids: 22.1;NK-cells: 45.3;Plasma cells: 21.4;T-cells: 26.1" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Group enriched" "Detected in some" 5 "Daudi: 88.2;U-698: 127.4" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051363, HPA051903" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 16: Immune cells - Immune response" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 63: NK-cells & T-cells - Immune response" "Plasma membrane, Cytosol" "HPA051363: AB_2681454, HPA051903: AB_2681658" "prognostic favorable (9.42e-4)" "prognostic favorable (2.78e-4)" "unprognostic (8.65e-2)" "prognostic favorable (9.53e-4)" "unprognostic (5.85e-2)" "prognostic favorable (7.34e-5)" "unprognostic (3.16e-3)" "unprognostic (9.78e-2)" "prognostic favorable (1.25e-4)" "unprognostic (2.31e-3)" "unprognostic (2.09e-1)" "unprognostic (1.57e-1)" "prognostic unfavorable (2.09e-6)" "unprognostic (2.78e-1)" "unprognostic (1.01e-1)" "unprognostic (2.33e-2)" "unprognostic (8.21e-3)" 1.7 1.1 0.2 20.6 0.2 3.2 2.2 0.8 0.4 2.0 0.3 3.8 2.7 1.3 1.4 2.1 1.3 4.6 1.0 0.2 0.1 0.9 4.0 4.4 61.7 0.3 0.1 1.2 0.9 0.2 0.2 1.8 0.3 1.3 3.5 0.1 2.2 0.5 0.4 0.6 13.8 1.4 0.1 32.2 5.5 1.2 0.4 19.3 1.7 0.5 48.6 5.7 1.2 0.3 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 88.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 6.7 0.0 0.1 0.0 0.6 0.1 0.0 0.0 0.0 0.0 0.0 0.0 23.6 0.8 0.1 0.0 0.0 21.8 1.3 0.1 0.7 0.0 0.2 0.0 1.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.1 0.0 0.2 0.0 0.0 0.1 14.2 127.4 0.0 0.6 0.0 11.2 0.3 23.1 56.1 1.0 38.9 36.2 35.6 71.4 0.3 35.4 19.5 39.5 2.5 41.3 3.1 1.0 45.6 22.2 0.2 0.2 0.8 0.4 0.2 0.1 0.3 0.1 0.3 0.1 0.4 0.3 0.1 0.0 1.3 0.0 23.6 0.4 0.2 0.0 0.0 0.0 0.1 0.3 0.1 0.0 0.0 0.0 0.0 0.0 19.7 0.1 0.0 0.1 9.4 0.1 0.1 0.3 0.0 3.2 0.0 0.2 0.0 0.4 0.5 0.1 1.3 0.0 3.3 1.1 1.1 0.0 0.0 0.0 0.0 4.3 0.8 22.1 0.0 1.1 0.0 0.0 1.6 0.0 45.3 0.0 0.0 0.1 0.1 0.0 21.4 0.2 0.0 0.2 0.0 0.0 0.0 0.2 0.1 0.1 0.2 0.1 0.3 0.0 26.1 0.0 0.0 0.0 SLC12A2 "BSC, BSC2, NKCC1, PPP1R141" ENSG00000064651 "Solute carrier family 12 member 2" P55011 5 128083766-128189677 "FDA approved drug targets, Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Potassium transport, Sodium transport, Symport, Transport" "FDA approved drug targets" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "salivary gland: 75.6" "Cell type enhanced" "Detected in all" "Intestinal goblet cells: 480.6;Oligodendrocytes: 566.6;Undifferentiated cells: 370.0" "Cancer enhanced" "Detected in all" "colorectal cancer: 54.3" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 6.4" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "OE19: 153.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA020130, HPA063697" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 45: Intestine - Brush border" "Cluster 21: OE19 - Mitochondria" "Cluster 27: Mucus-secreting cells - Mucin production" Vesicles "Plasma membrane" "HPA020130: AB_1854502, HPA063697: AB_2685094" "unprognostic (4.61e-2)" "unprognostic (2.63e-1)" "unprognostic (4.20e-3)" "prognostic favorable (8.60e-4)" "unprognostic (3.99e-1)" "unprognostic (5.65e-3)" "unprognostic (1.44e-3)" "unprognostic (1.81e-1)" "unprognostic (3.30e-1)" "unprognostic (2.95e-2)" "unprognostic (7.22e-2)" "unprognostic (1.39e-1)" "prognostic favorable (7.09e-4)" "unprognostic (1.63e-1)" "unprognostic (2.30e-1)" "unprognostic (3.79e-1)" "unprognostic (3.88e-3)" 8.4 17.5 15.0 10.8 48.4 4.4 43.9 46.3 23.2 7.2 40.4 48.5 41.7 8.4 2.4 4.6 6.0 39.4 6.1 13.5 31.1 6.6 4.2 10.3 5.6 40.8 43.1 5.4 6.1 14.7 5.5 4.9 38.6 23.5 58.9 16.8 75.6 2.6 15.4 28.4 49.1 10.2 27.1 4.5 61.8 8.0 32.4 4.1 8.6 8.3 6.0 7.3 3.5 64.8 13.5 65.3 65.8 25.6 16.1 10.4 13.6 12.2 9.1 8.6 8.9 26.4 20.9 19.9 16.1 10.6 7.8 39.5 12.7 14.0 13.2 20.0 15.8 5.7 11.4 3.8 4.9 7.3 9.5 11.1 5.0 19.1 11.2 6.4 14.2 8.5 9.4 13.2 13.4 14.2 13.0 6.1 7.7 153.6 21.1 7.1 18.5 8.2 10.0 45.0 11.5 7.3 24.6 10.6 9.9 7.0 5.9 3.7 24.1 21.2 14.2 16.3 15.7 11.0 10.7 21.6 11.2 4.2 17.6 0.3 0.4 0.2 1.1 0.7 1.9 1.7 1.0 1.4 0.6 2.1 1.1 1.6 0.2 2.4 0.5 6.4 1.1 0.3 15.0 48.4 46.3 23.2 13.5 31.1 40.8 43.1 38.6 27.1 32.4 64.8 38.3 16.0 46.2 23.8 20.5 22.9 20.1 44.9 10.8 76.6 186.9 86.7 18.0 137.2 52.1 33.1 127.2 1.4 34.4 48.2 1.9 68.6 55.8 33.1 43.1 44.2 74.4 2.5 160.6 48.2 2.7 21.3 199.3 38.4 18.4 28.8 12.8 8.8 4.2 80.8 73.2 480.6 57.0 8.6 12.0 95.3 85.4 11.4 204.5 105.9 2.5 22.6 11.3 55.3 566.6 50.1 60.6 29.0 20.2 131.6 38.8 10.6 19.6 86.4 72.3 33.9 64.3 29.1 27.1 14.9 30.0 1.4 21.1 14.1 370.0 21.5 SLC16A1 "MCT, MCT1" ENSG00000155380 "Solute carrier family 16 member 1" P53985 1 112911847-112957593 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 158.4;Granulosa cells: 322.8;Muller glia cells: 184.8;Rod photoreceptor cells: 277.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "T-reg: 6.1" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003324, CAB017489, HPA071055, CAB079035" Enhanced Supported Enhanced "Plasma membrane,Cell Junctions" NA NA "Cluster 4: T-regs - Cell cycle regulation" "Cluster 39: Non-specific - Mitochondria" "Cluster 5: NTERA-2 - Transcription" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane, Cell Junctions" "CAB017489: AB_2189197, CAB079035: , HPA003324: AB_1856982, HPA071055: AB_2686337" "unprognostic (1.19e-1)" "unprognostic (1.61e-2)" "unprognostic (2.97e-1)" "prognostic unfavorable (8.37e-6)" "unprognostic (1.53e-1)" "unprognostic (2.89e-2)" "unprognostic (2.15e-3)" "prognostic unfavorable (4.05e-4)" "unprognostic (6.92e-2)" "unprognostic (6.31e-3)" "prognostic unfavorable (2.10e-4)" "unprognostic (1.18e-1)" "prognostic unfavorable (6.78e-8)" "unprognostic (1.30e-1)" "unprognostic (2.31e-1)" "unprognostic (1.04e-2)" "unprognostic (1.53e-3)" 20.7 10.4 35.7 11.8 36.1 4.3 7.5 37.8 99.4 7.1 37.8 46.8 32.5 28.6 22.8 15.3 13.1 14.8 67.9 33.5 35.2 11.4 55.6 4.9 9.5 38.6 35.9 7.9 2.0 10.0 5.2 34.0 37.0 14.4 35.3 68.9 3.5 11.2 67.5 13.0 16.6 39.2 37.0 6.6 26.6 29.8 38.3 11.7 8.6 59.6 11.6 11.9 7.1 38.2 111.1 24.0 86.9 74.3 61.9 52.1 272.7 64.6 51.1 52.0 80.9 85.4 67.1 113.8 82.3 61.6 32.6 113.1 126.3 124.8 96.8 75.6 105.2 108.9 63.4 112.9 104.6 123.2 9.9 72.2 144.6 75.7 146.4 79.2 131.4 53.8 131.3 78.0 61.9 19.9 70.2 70.1 271.4 36.7 74.5 67.9 130.7 92.8 67.3 1.9 86.9 46.5 121.8 3.8 97.5 130.0 3.7 48.9 80.9 45.4 72.0 89.3 93.1 39.7 33.9 116.7 137.1 78.5 56.0 0.0 1.4 0.0 1.5 1.6 1.7 0.9 1.8 2.0 2.5 0.3 0.8 1.5 0.1 0.6 0.3 0.2 6.1 0.8 35.7 36.1 37.8 99.4 33.5 35.2 38.6 35.9 37.0 37.0 38.3 38.2 15.1 0.0 2.6 8.5 16.5 89.3 6.5 39.9 87.6 16.9 16.5 9.9 126.3 10.0 5.7 0.0 158.4 77.4 20.3 99.8 0.0 2.5 107.2 14.3 70.7 22.8 3.5 20.2 9.8 3.3 67.6 32.8 67.2 35.8 8.9 322.8 6.4 37.5 15.4 20.2 11.6 17.3 20.3 9.0 15.7 118.3 11.8 12.8 39.2 20.6 4.3 184.8 0.0 9.0 23.8 7.4 7.7 7.5 25.5 16.5 9.3 10.8 3.9 277.5 0.0 38.2 22.1 45.3 23.6 29.6 39.5 46.0 20.9 49.6 23.3 1.3 SLC16A3 "MCT3, MCT4" ENSG00000141526 "Solute carrier family 16 member 3" O15427 17 82217934-82261129 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 198.3" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 1667.1;Syncytiotrophoblasts: 748.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 109.1" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB017490, HPA021451" Approved Supported "Nuclear membrane,Plasma membrane" NA NA 260000 "Cluster 52: Eosinophils - Transcription" "Cluster 59: Non-specific - Translation" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 38: Extravillous trophoblasts - Unknown function" "Plasma membrane" "Nuclear membrane" "CAB017490: AB_2189333, HPA021451: AB_1853663" "unprognostic (2.49e-1)" "prognostic unfavorable (6.07e-4)" "unprognostic (4.31e-1)" "unprognostic (1.74e-1)" "unprognostic (3.47e-3)" "unprognostic (4.26e-3)" "prognostic unfavorable (1.19e-7)" "prognostic unfavorable (2.02e-5)" "unprognostic (2.52e-1)" "unprognostic (2.09e-2)" "unprognostic (4.35e-3)" "unprognostic (1.53e-1)" "prognostic unfavorable (3.71e-7)" "unprognostic (2.27e-1)" "unprognostic (4.00e-2)" "unprognostic (8.00e-2)" "unprognostic (1.36e-2)" 30.4 16.9 3.8 25.3 5.8 22.7 15.7 6.6 9.7 26.2 5.0 28.9 11.6 11.6 1.3 42.4 18.5 12.8 26.0 4.5 7.3 48.2 11.3 46.4 5.7 17.3 8.5 9.1 5.8 2.5 12.1 24.7 11.9 19.6 5.7 5.7 27.5 5.9 198.3 8.4 22.9 6.0 8.4 57.5 22.0 32.0 13.8 2.9 29.1 73.2 5.2 26.3 28.5 15.1 52.8 24.4 0.6 1.3 7.8 28.8 51.7 225.6 107.7 117.4 142.2 10.1 119.1 0.7 158.0 122.5 127.9 18.9 15.6 242.0 51.8 78.1 1.2 87.4 144.0 236.4 164.1 105.2 111.5 64.8 38.2 77.0 38.5 185.8 69.1 2.2 1.0 26.6 116.1 14.0 1.4 166.3 1.9 22.1 223.5 0.9 1.6 33.2 75.9 3.0 2.9 1.7 196.7 166.9 3.2 20.4 25.4 131.4 124.0 281.7 5.1 4.5 200.9 97.3 1.9 3.9 140.2 94.7 3.0 56.6 32.6 92.1 9.6 30.4 13.4 8.1 7.7 10.5 24.1 6.2 4.2 5.3 109.1 25.3 31.4 15.2 7.3 16.0 3.8 5.8 6.6 9.7 4.5 7.3 17.3 8.5 11.9 8.4 13.8 15.1 19.2 9.6 9.8 3.6 27.9 6.5 47.5 210.1 2.8 13.4 3.2 2.5 6.1 4.3 182.3 57.0 4.2 67.6 72.4 216.7 0.0 136.1 3.0 33.7 15.4 29.9 20.9 9.1 0.3 18.0 1667.1 17.2 45.3 65.1 75.0 15.9 16.8 1.1 271.0 127.9 0.3 28.3 148.5 99.9 84.6 3.8 3.1 168.6 14.2 9.4 184.9 20.3 40.2 0.0 1.0 305.5 190.2 3.8 35.7 16.5 62.4 5.6 91.1 11.6 0.0 1.6 50.5 1.9 9.5 1.6 6.7 748.8 38.5 0.8 33.4 119.6 SLC16A7 MCT2 ENSG00000118596 "Solute carrier family 16 member 7" O60669 12 59596029-59789855 "Metabolic proteins, Predicted membrane proteins, Transporters" "Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "heart muscle: 34.4" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 135.4;Early spermatids: 117.3;Excitatory neurons: 150.5;Inhibitory neurons: 128.2;Late spermatids: 135.5" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enriched" "Detected in all" 5 "cerebellum: 22.2" HPA005911 Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 18: U-2197 - ECM organization" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Nucleoplasm "HPA005911: AB_1853659" "unprognostic (1.52e-2)" "unprognostic (9.47e-3)" "unprognostic (9.48e-2)" "unprognostic (3.22e-2)" "unprognostic (1.17e-1)" "unprognostic (1.29e-2)" "unprognostic (5.35e-2)" "unprognostic (8.09e-2)" "unprognostic (1.90e-1)" "unprognostic (1.04e-1)" "unprognostic (8.39e-2)" "unprognostic (9.79e-2)" "prognostic favorable (8.85e-5)" "unprognostic (2.19e-3)" "unprognostic (3.11e-1)" "unprognostic (9.35e-2)" "unprognostic (2.45e-2)" 20.1 6.8 1.2 3.9 1.2 4.7 4.1 5.7 3.9 2.8 3.7 2.0 1.6 3.0 1.5 6.3 2.2 5.4 34.4 1.3 0.3 11.6 3.9 4.5 4.9 2.9 0.4 2.7 9.8 1.0 1.5 1.6 2.9 1.6 2.5 1.8 2.9 1.6 1.8 7.9 2.5 3.5 0.5 6.3 10.0 2.2 1.3 4.5 1.6 3.6 4.2 4.0 3.0 4.2 0.2 3.6 0.8 0.5 10.9 18.1 0.2 8.8 8.1 4.0 3.4 0.3 6.3 5.8 2.5 16.8 3.8 0.8 1.0 1.7 6.0 2.4 0.5 10.7 12.6 0.5 5.9 14.3 0.1 8.5 3.9 1.4 10.3 7.5 1.6 7.2 0.2 13.0 6.5 3.4 5.5 3.2 0.8 1.2 3.3 0.5 0.1 2.7 9.5 16.0 3.0 1.0 0.1 0.4 6.2 0.7 0.5 2.4 0.0 8.6 3.3 15.6 0.5 11.3 0.2 10.0 10.2 0.1 1.6 0.2 1.5 0.0 4.2 3.2 5.6 1.8 3.3 3.6 1.5 4.1 3.5 5.8 0.1 3.0 8.4 2.1 3.8 2.3 1.2 1.2 5.7 3.9 1.3 0.3 2.9 0.4 2.9 0.5 1.3 4.2 15.3 28.9 21.4 13.7 28.4 10.1 7.8 9.9 16.5 24.5 1.5 3.9 135.4 90.1 16.5 46.0 10.4 0.3 29.7 0.8 23.5 53.3 117.3 2.1 25.0 22.0 0.0 2.5 150.5 67.1 0.3 36.2 7.1 9.1 10.1 4.7 9.3 14.5 3.6 8.4 128.2 27.2 6.1 32.7 6.1 135.5 6.8 24.8 3.6 14.0 14.9 1.3 37.0 63.8 82.8 28.0 1.2 10.1 26.3 8.1 1.0 0.7 14.4 6.0 6.6 14.0 18.9 4.2 4.5 61.5 12.6 0.7 35.8 80.1 1.5 3.4 SLC17A5 "AST, ISSD, NSD, SD, SIALIN, SIASD, SLD" ENSG00000119899 "Solute carrier family 17 member 5" Q9NRA2 6 73593379-73653992 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 7 "parathyroid gland: 310.5" "Low cell type specificity" "Detected in many" "Cancer enhanced" "Detected in all" "thyroid cancer: 47.0" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "ASC diff: 99.9;ASC TERT1: 74.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044479 Supported "Plasma membrane,Cytosol" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA044479: " "unprognostic (6.48e-3)" "unprognostic (7.95e-3)" "unprognostic (9.23e-2)" "unprognostic (1.45e-2)" "unprognostic (1.48e-1)" "unprognostic (1.08e-1)" "unprognostic (2.59e-3)" "unprognostic (4.44e-2)" "unprognostic (4.18e-2)" "unprognostic (2.60e-1)" "unprognostic (3.14e-2)" "unprognostic (8.29e-2)" "unprognostic (4.59e-2)" "unprognostic (2.50e-1)" "unprognostic (1.40e-1)" "prognostic favorable (3.52e-4)" "unprognostic (1.09e-1)" 10.4 10.5 5.9 6.4 6.0 6.8 13.8 6.2 7.0 10.7 5.9 20.4 16.4 9.4 44.6 8.4 5.3 10.4 8.5 6.5 8.5 31.9 17.6 13.2 5.3 6.5 7.0 4.0 11.6 310.5 9.9 21.7 7.8 16.8 22.1 18.3 30.3 14.7 5.4 7.1 21.1 10.6 5.7 7.0 14.4 6.1 7.1 4.5 43.5 6.2 5.6 12.6 6.3 7.6 7.4 9.9 9.7 15.6 99.9 74.2 12.8 23.8 59.4 6.3 22.0 6.6 17.6 6.8 11.2 32.9 14.8 12.6 13.7 5.9 11.2 4.8 15.5 2.8 5.1 15.4 19.4 5.6 10.8 34.2 8.8 14.2 9.7 26.4 16.2 9.0 7.1 7.2 22.3 4.9 2.3 3.3 7.1 30.9 5.7 5.0 12.1 28.5 16.0 20.2 3.8 6.7 4.8 14.0 14.4 14.0 6.3 34.1 23.5 3.0 2.8 12.1 5.7 20.4 30.6 1.9 10.5 11.6 9.0 13.3 7.9 3.3 6.0 7.4 5.8 3.9 6.6 5.8 7.6 2.4 5.4 6.0 5.7 8.9 4.8 5.5 6.6 4.9 5.9 6.0 6.2 7.0 6.5 8.5 6.5 7.0 7.8 5.7 7.1 7.6 8.8 22.4 20.7 16.3 8.2 9.6 13.2 13.7 5.7 8.2 22.6 5.5 6.8 18.6 17.4 51.5 29.2 19.4 11.0 46.4 3.9 14.2 36.6 16.6 7.8 13.8 12.1 3.8 47.7 13.7 13.5 25.8 14.8 19.6 14.5 3.2 23.9 32.9 64.6 0.0 46.8 47.7 20.3 24.8 22.7 48.3 7.5 25.4 10.6 14.0 11.2 8.3 13.4 17.6 16.3 19.2 17.5 11.3 20.6 29.1 23.9 36.3 21.5 28.9 0.0 10.5 9.1 8.4 3.6 10.2 11.2 22.8 11.0 2.9 19.2 30.7 SLC1A6 EAAT4 ENSG00000105143 "Solute carrier family 1 member 6" P48664 19 14950034-15022990 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in some" 7 "brain: 88.2;testis: 28.0" "Cell type enhanced" "Detected in some" "Bipolar cells: 17.1;Early spermatids: 35.3;Horizontal cells: 23.5;Late spermatids: 31.8;Syncytiotrophoblasts: 40.0" "Cancer enriched" "Detected in some" 7 "urothelial cancer: 5.2" "Region enriched" "Detected in all" 6 "cerebellum: 88.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 7.4;NTERA-2: 6.1;U-698: 28.3" "Region enriched" "Detected in all" 6 "cerebellum: 136.3" "Region enhanced" "Detected in all" "cerebellum: 53.8" "HPA041505, HPA044066" Enhanced Supported Supported "Plasma membrane,Intermediate filaments" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 27: U-698-M & Daudi - Adaptive immune response" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Intermediate filaments" "HPA041505: AB_2677520, HPA044066: AB_2678796" "unprognostic (3.62e-2)" "unprognostic (1.35e-1)" "unprognostic (4.41e-2)" "unprognostic (1.52e-1)" "unprognostic (1.12e-1)" "unprognostic (5.94e-3)" "unprognostic (8.90e-2)" "unprognostic (6.52e-4)" "unprognostic (1.55e-1)" "unprognostic (5.40e-3)" "unprognostic (1.11e-2)" "unprognostic (9.92e-2)" "unprognostic (1.35e-1)" "unprognostic (5.57e-2)" "prognostic unfavorable (6.88e-6)" 0.1 0.2 9.1 0.2 10.8 0.9 0.4 88.2 14.4 0.1 0.5 0.2 0.3 0.4 1.7 0.1 0.2 0.2 0.2 14.5 5.0 0.1 0.2 0.2 0.3 3.7 7.5 0.3 0.6 0.9 0.3 0.7 8.1 0.5 0.3 2.3 0.4 0.5 0.3 8.6 0.3 0.2 3.2 0.4 0.2 28.0 6.6 0.2 0.3 0.1 0.3 0.1 0.1 5.1 0.1 0.1 0.3 0.4 0.2 0.2 0.9 0.1 0.1 0.1 0.1 0.2 0.2 0.1 0.1 0.2 0.1 1.4 7.4 0.2 0.1 0.2 0.1 0.2 0.4 0.3 0.0 0.2 0.1 0.1 0.2 0.1 0.1 0.2 0.1 0.2 0.1 0.6 0.1 0.6 0.0 0.5 6.1 0.0 0.1 0.1 0.1 0.1 0.1 0.3 0.5 0.2 0.2 2.8 0.0 1.1 0.3 0.1 0.0 0.3 1.1 0.3 0.1 0.5 0.1 28.3 0.1 0.3 0.1 0.3 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.1 0.3 0.0 0.0 0.1 0.0 0.0 9.1 10.8 88.2 14.4 14.5 5.0 3.7 7.5 8.1 3.2 6.6 5.1 0.0 0.0 0.0 0.7 0.0 3.2 0.7 0.0 0.0 17.1 0.0 0.1 2.1 0.0 0.0 1.8 0.0 1.9 0.0 0.0 0.0 0.0 35.3 0.0 0.1 0.1 0.0 0.0 8.2 0.4 9.9 0.4 0.0 0.0 0.0 5.8 0.0 0.0 0.5 23.5 8.6 0.0 0.0 0.0 0.7 31.8 0.6 0.0 0.0 1.0 0.0 0.7 0.0 4.5 0.9 0.0 0.0 0.7 0.0 0.2 0.0 0.2 0.0 0.8 0.0 0.0 0.4 2.2 6.3 0.0 6.8 40.0 0.0 0.0 0.0 0.1 SLC22A16 "CT2, FLIPT2, OAT6, OKB1" ENSG00000004809 "Solute carrier family 22 member 16" Q86VW1 6 110424687-110476641 "Metabolic proteins, Predicted membrane proteins, Transporters" "Differentiation, Ion transport, Spermatogenesis, Transport" "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "bone marrow: 20.5;testis: 21.4" "Group enriched" "Detected in some" 10 "Early spermatids: 34.9;Erythroid cells: 60.4;Late spermatids: 31.8;Spermatocytes: 43.1" "Cancer enriched" "Detected in single" 5 "endometrial cancer: 0.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in some" "basophil: 5.7;classical monocyte: 6.9" "Group enriched" "Detected in many" 56 "dendritic cells: 4.0;granulocytes: 5.7;monocytes: 6.9" "Group enriched" "Detected in some" 18 "NB-4: 16.9;REH: 14.6;THP-1: 53.1;U-937: 30.9" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA036902 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 43: THP-1 - Innate immune response" "Cluster 6: Erythroid cells - Oxygen transport" "Plasma membrane, Cytosol" "HPA036902: AB_10672274" "unprognostic (1.01e-1)" "unprognostic (1.88e-2)" "unprognostic (5.11e-3)" "unprognostic (2.19e-3)" "unprognostic (2.70e-4)" "unprognostic (1.45e-1)" "unprognostic (8.15e-2)" "unprognostic (6.93e-2)" "unprognostic (1.48e-2)" "unprognostic (4.98e-2)" "unprognostic (1.02e-3)" "unprognostic (2.49e-1)" "unprognostic (2.61e-6)" "unprognostic (5.78e-4)" "unprognostic (2.72e-2)" "unprognostic (2.74e-2)" "unprognostic (2.65e-2)" 0.3 0.0 0.1 0.6 0.2 20.5 0.1 0.2 0.2 0.2 0.0 0.0 0.0 0.9 0.0 0.0 0.1 0.1 0.0 0.1 0.1 0.0 0.1 0.4 0.0 0.2 0.2 0.0 0.0 3.8 0.0 0.5 0.3 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 1.8 0.2 0.5 0.0 21.4 0.1 1.2 0.0 0.1 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 16.9 0.0 0.0 0.0 14.6 0.0 0.0 0.0 0.0 0.4 0.2 0.0 0.0 0.0 0.0 0.0 53.1 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 30.9 0.0 5.7 6.9 1.3 0.0 1.5 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.5 0.1 0.2 0.2 0.2 0.1 0.1 0.2 0.2 0.3 0.2 0.1 0.4 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.9 0.4 0.1 0.0 0.0 60.4 0.1 0.0 0.1 0.3 0.0 0.2 0.0 0.0 0.0 0.0 2.7 0.0 0.1 0.0 0.0 1.8 0.5 31.8 1.5 1.1 0.0 0.0 1.8 0.0 0.0 0.0 0.5 0.0 0.0 0.4 0.3 0.0 0.0 0.0 4.0 0.0 0.0 0.0 0.1 43.1 0.4 0.0 0.4 0.0 0.1 0.0 0.0 0.0 SLC2A12 "GLUT12, GLUT8" ENSG00000146411 "Solute carrier family 2 member 12" Q8TD20 6 133987581-134052624 "Metabolic proteins, Predicted membrane proteins, Transporters" "Sugar transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "choroid plexus: 87.3" "Cell type enhanced" "Detected in many" "Astrocytes: 24.8;Oligodendrocytes: 14.5;Syncytiotrophoblasts: 36.7" "Cancer enriched" "Detected in many" 6 "prostate cancer: 18.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "CAPAN-2: 7.6;hTERT-RPE1: 14.8;SuSa: 21.7;U-2 OS: 7.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031593, HPA031594" Approved Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 12: NES - Nervous system development" "Cluster 18: Syncytiotrophoblasts - Pregnancy hormone signaling" "Plasma membrane" "Cell Junctions" "HPA031593: AB_10600810, HPA031594: AB_2673948" "unprognostic (2.06e-1)" "unprognostic (1.21e-1)" "unprognostic (1.69e-2)" "unprognostic (5.55e-3)" "unprognostic (2.18e-1)" "unprognostic (6.02e-2)" "unprognostic (2.24e-3)" "unprognostic (2.54e-2)" "unprognostic (2.08e-2)" "unprognostic (3.69e-2)" "unprognostic (2.38e-1)" "unprognostic (1.83e-1)" "unprognostic (2.33e-3)" "unprognostic (3.04e-1)" "unprognostic (1.65e-1)" "unprognostic (1.04e-2)" "unprognostic (1.55e-3)" 0.5 1.0 3.6 0.3 4.8 0.0 1.1 7.8 4.6 3.0 87.3 2.1 7.3 8.2 2.1 6.1 2.8 2.6 10.7 5.7 2.6 5.8 6.8 3.1 0.1 2.3 3.1 1.2 1.1 2.3 1.4 1.6 2.5 22.4 1.0 2.3 5.1 9.3 3.8 2.7 9.8 3.1 1.6 0.1 14.3 0.4 3.4 1.0 0.2 4.1 1.2 3.5 1.2 3.1 2.5 0.9 2.3 0.0 1.4 0.7 0.1 1.5 5.4 0.7 2.9 0.0 7.6 0.3 1.2 0.1 5.7 5.9 0.0 0.5 1.0 0.0 5.3 0.0 0.8 0.1 0.2 0.0 0.0 1.0 0.5 0.6 0.1 14.8 0.4 0.4 0.5 0.8 0.1 0.8 0.1 0.1 2.0 0.0 0.5 0.0 1.0 2.2 1.6 0.8 0.2 0.7 0.1 2.1 0.0 21.7 0.1 0.0 0.1 0.2 7.6 0.2 0.9 3.2 2.4 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 3.6 4.8 7.8 4.6 5.7 2.6 2.3 3.1 2.5 1.6 3.4 3.1 0.2 0.0 7.7 24.8 0.1 2.0 1.0 3.3 8.6 0.4 0.5 2.2 6.3 0.0 2.2 0.0 0.0 2.0 0.1 1.2 3.9 1.5 0.1 3.4 0.4 2.3 4.2 0.0 8.0 0.2 0.6 2.2 2.6 1.6 0.0 0.4 0.0 1.1 0.3 0.0 3.2 0.2 6.1 0.0 0.3 0.0 0.0 0.1 0.0 4.7 0.1 9.8 0.0 4.5 14.5 1.1 2.4 1.5 1.6 10.5 0.5 0.5 10.4 0.5 0.0 2.1 1.3 0.0 0.0 8.6 1.8 36.7 0.2 3.5 0.4 1.3 SLC30A1 "ZNT1, ZRC1" ENSG00000170385 "Solute carrier family 30 member 1" Q9Y6M5 1 211571568-211579161 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 86.1" "Cell type enhanced" "Detected in many" "Hepatocytes: 94.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015275, HPA049000" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 10: Basophils - Unknown function" "Cluster 85: Liver - Metabolism" "Cluster 28: BEWO - Transcription regulation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Vesicles "HPA015275: AB_1857083, HPA049000: AB_2680593" "unprognostic (1.13e-1)" "unprognostic (2.67e-3)" "unprognostic (6.94e-2)" "unprognostic (1.81e-3)" "unprognostic (3.47e-1)" "unprognostic (1.80e-1)" "unprognostic (2.27e-2)" "unprognostic (1.82e-3)" "unprognostic (4.72e-1)" "unprognostic (1.01e-1)" "unprognostic (1.42e-3)" "unprognostic (4.78e-2)" "unprognostic (2.23e-2)" "unprognostic (3.03e-1)" "unprognostic (2.55e-1)" "unprognostic (1.02e-1)" "unprognostic (4.53e-2)" 14.8 18.0 15.7 10.9 17.0 29.8 8.5 15.2 19.3 18.6 27.8 15.4 28.2 10.8 9.9 8.0 12.5 12.4 10.0 16.9 15.4 20.5 86.1 7.2 6.1 17.9 17.3 7.8 11.3 10.3 4.6 10.1 16.8 7.8 13.6 6.1 9.3 7.9 1.8 16.0 19.9 11.6 16.7 15.4 9.5 13.4 18.9 4.5 16.9 4.8 7.1 12.2 7.5 13.2 10.3 15.0 7.7 9.9 32.4 14.9 70.5 27.3 19.3 13.8 13.6 6.4 46.6 5.8 24.1 24.4 19.3 17.2 11.5 15.4 16.4 15.0 9.3 4.7 28.8 14.7 18.1 15.8 10.0 22.5 37.5 17.7 28.4 20.5 8.6 3.4 18.7 25.5 17.2 9.1 3.2 9.9 24.2 10.6 12.0 10.0 3.7 20.4 42.5 26.4 7.8 13.7 26.7 13.6 62.7 14.2 7.0 20.2 14.6 10.4 24.8 35.4 22.1 11.9 19.0 4.5 9.8 15.7 9.3 1.4 1.3 0.5 0.4 1.5 0.5 0.2 0.3 0.2 0.9 0.1 0.3 0.4 0.1 0.4 1.2 0.5 0.3 0.4 15.7 17.0 15.2 19.3 16.9 15.4 17.9 17.3 16.8 16.7 18.9 13.2 29.7 9.6 9.8 3.9 8.8 28.6 8.2 3.0 16.5 11.0 24.9 14.7 21.0 18.6 4.2 36.8 6.2 11.6 19.9 54.5 1.9 6.9 44.0 37.0 19.1 27.3 9.5 26.1 0.6 12.5 32.7 15.9 8.6 66.4 5.1 7.5 17.9 94.9 32.0 6.7 0.6 22.8 2.0 27.2 14.5 6.8 9.9 25.5 21.4 3.7 18.8 29.0 1.0 1.0 0.1 9.5 41.7 7.5 8.6 13.9 49.2 29.8 6.4 9.4 6.6 15.9 11.7 37.9 17.4 24.2 46.2 24.5 14.2 14.8 23.3 13.7 SLC39A2 ZIP2 ENSG00000165794 "Solute carrier family 39 member 2" Q9NP94 14 20999255-21001871 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Transport, Zinc transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 18.8;seminal vesicle: 33.2;skin 1: 37.5" "Cell type enhanced" "Detected in some" "Muller glia cells: 22.3;Squamous epithelial cells: 12.0;Suprabasal keratinocytes: 6.0;Urothelial cells: 4.4" "Group enriched" "Detected in many" 4 "cervical cancer: 5.1;colorectal cancer: 3.3;head and neck cancer: 6.1;melanoma: 1.9;urothelial cancer: 6.7" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in single" 71 "HaCaT: 23.2" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA030489, HPA073231" Uncertain Approved "Plasma membrane,Cytoplasmic bodies" NA NA "Cluster 31: Skin - Epidermis development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 5: Muller glia cells - Visual perception" "Plasma membrane" "Cytoplasmic bodies" "HPA030489: AB_10601488, HPA073231: " "unprognostic (2.76e-2)" "unprognostic (4.86e-2)" "unprognostic (9.72e-2)" "unprognostic (2.37e-1)" "unprognostic (2.46e-1)" "unprognostic (2.71e-1)" "unprognostic (3.42e-1)" "unprognostic (1.70e-1)" "unprognostic (4.43e-1)" "unprognostic (6.20e-3)" "unprognostic (3.31e-1)" "unprognostic (2.80e-1)" "unprognostic (3.62e-2)" "unprognostic (1.91e-1)" "unprognostic (5.80e-2)" "unprognostic (3.71e-1)" "unprognostic (2.30e-3)" 0.1 0.0 0.2 0.1 0.2 0.0 1.9 0.3 0.3 8.0 0.2 1.9 0.0 0.3 0.1 18.8 0.5 0.4 0.2 0.2 0.2 0.0 0.1 0.1 0.0 0.2 0.3 0.0 0.0 2.3 0.1 0.3 0.2 12.2 1.3 3.7 4.1 33.2 0.2 37.5 0.1 0.2 0.3 0.0 0.0 0.1 0.3 2.8 0.0 0.0 2.7 0.3 14.1 0.4 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 23.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 0.0 0.3 0.2 0.0 0.2 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.3 0.3 0.2 0.2 0.2 0.3 0.2 0.3 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.8 1.1 0.9 0.0 0.2 0.8 0.3 0.4 0.0 0.7 0.0 2.1 0.1 0.0 0.5 0.0 0.0 0.2 0.6 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.8 0.0 1.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 22.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 2.8 0.2 0.0 0.0 0.9 0.0 0.0 0.2 0.0 0.0 12.0 6.0 0.3 0.0 0.0 1.4 4.4 SLC3A2 "4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE" ENSG00000168003 "Solute carrier family 3 member 2" P08195 11 62856004-62888880 "Cancer-related genes, CD markers, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Syncytiotrophoblasts: 780.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "hTCEpi: 1441.0;SiHa: 1287.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010455, HPA017980" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 170000000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Nucleoplasm, Plasma membrane" "CAB010455: AB_638288, HPA017980: AB_2669723" "unprognostic (1.79e-1)" "unprognostic (9.61e-3)" "unprognostic (3.59e-1)" "unprognostic (7.87e-3)" "unprognostic (2.06e-1)" "unprognostic (2.41e-3)" "prognostic unfavorable (8.17e-4)" "unprognostic (2.09e-3)" "unprognostic (2.62e-1)" "unprognostic (4.16e-2)" "unprognostic (2.29e-2)" "unprognostic (3.71e-1)" "prognostic favorable (8.22e-4)" "unprognostic (2.92e-2)" "unprognostic (5.52e-3)" "unprognostic (3.49e-3)" "prognostic unfavorable (1.48e-4)" 103.3 105.6 130.5 46.7 138.0 122.0 108.9 140.1 160.4 101.6 115.6 60.6 51.5 97.2 65.3 112.9 94.0 35.8 52.0 123.1 133.3 171.2 71.9 117.8 34.9 138.4 132.6 93.0 109.7 189.7 65.3 55.4 134.0 100.8 23.1 22.8 110.6 41.9 122.3 127.1 79.7 33.8 135.8 77.4 90.2 65.1 154.5 30.1 110.2 26.0 28.8 77.7 95.1 130.6 155.5 675.7 60.2 213.2 89.7 69.7 596.7 267.5 106.2 154.0 126.3 643.3 293.0 173.9 290.5 185.4 284.5 540.0 123.1 588.9 84.3 319.3 114.0 117.5 422.4 299.2 825.7 136.0 169.4 144.9 1441.0 175.3 528.8 46.2 83.6 380.7 232.9 347.4 95.1 792.6 149.8 181.3 106.9 222.5 214.2 153.8 92.7 341.8 113.9 84.0 112.5 53.5 1287.0 499.6 948.5 121.2 161.5 182.6 146.2 138.3 200.0 204.4 195.5 436.0 556.1 561.2 135.0 225.1 418.0 37.8 149.0 49.7 117.9 147.4 157.7 58.3 107.3 122.1 88.6 72.1 90.1 97.2 31.2 90.3 123.9 304.7 112.5 186.3 130.5 138.0 140.1 160.4 123.1 133.3 138.4 132.6 134.0 135.8 154.5 130.6 97.8 48.1 37.3 91.1 78.8 218.1 244.2 321.7 399.5 58.4 124.2 120.8 13.4 30.0 141.1 49.7 66.7 222.5 136.2 109.6 33.2 161.9 31.5 122.0 96.3 149.2 84.3 117.7 16.9 151.1 143.7 102.9 71.4 179.7 84.3 43.2 99.2 27.0 202.9 53.8 25.1 60.4 223.8 54.1 140.9 28.9 30.4 141.5 224.1 29.0 104.7 188.4 40.2 21.1 11.3 130.6 58.7 30.5 140.9 156.9 120.7 227.4 63.4 61.2 6.6 71.8 114.6 21.3 31.9 160.7 150.6 780.7 118.1 52.4 60.7 194.9 SLC46A1 "HCP1, MGC9564, PCFT" ENSG00000076351 "Solute carrier family 46 member 1" Q96NT5 17 28394642-28407197 "Disease related genes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins, Transporters" Transport "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "intestine: 93.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 26.6;Hepatocytes: 27.8;Hofbauer cells: 25.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enriched" "Detected in many" 5 "CACO-2: 205.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" CAB011614 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 39: CACO-2 - Unknown function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "CAB011614: AB_2270597" "unprognostic (1.10e-1)" "unprognostic (8.62e-2)" "unprognostic (1.40e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (5.62e-4)" "unprognostic (9.11e-2)" "unprognostic (4.05e-2)" "unprognostic (1.36e-2)" "unprognostic (1.94e-1)" "unprognostic (3.80e-2)" "unprognostic (1.04e-3)" "unprognostic (6.15e-2)" "unprognostic (2.10e-3)" "unprognostic (2.16e-1)" "unprognostic (2.94e-1)" "unprognostic (2.15e-1)" "unprognostic (1.04e-1)" 6.7 24.8 8.1 5.7 10.6 3.4 5.7 14.7 9.2 5.6 26.7 5.7 93.9 4.6 8.5 2.4 13.4 4.6 4.6 8.0 8.4 7.5 27.3 6.9 5.5 11.2 9.7 8.7 11.2 15.0 15.5 8.2 10.4 7.4 5.6 8.7 12.5 9.0 3.6 2.3 40.5 5.5 9.8 11.1 5.5 3.1 10.0 23.4 6.4 2.8 2.1 5.0 2.6 12.1 5.4 22.5 7.4 12.2 5.9 1.3 22.9 6.3 4.6 5.1 5.7 205.4 6.4 0.4 3.6 3.4 14.8 17.3 8.4 14.1 4.3 13.1 19.6 0.2 14.0 17.6 2.1 0.1 10.1 2.8 25.3 5.3 15.8 7.1 0.4 1.8 8.9 1.2 0.9 7.2 0.1 0.6 4.4 5.2 2.9 0.3 6.0 2.7 4.0 11.8 19.4 10.2 43.6 20.1 2.4 10.1 15.6 3.4 0.6 0.8 8.6 1.2 6.6 9.0 11.1 0.3 1.2 1.3 4.7 5.2 0.9 0.6 0.4 3.0 0.7 1.6 0.4 0.3 1.4 0.8 0.5 0.8 1.0 1.6 2.6 0.5 0.9 0.5 8.1 10.6 14.7 9.2 8.0 8.4 11.2 9.7 10.4 9.8 10.0 12.1 1.2 12.8 5.3 7.5 1.0 0.4 1.9 2.8 4.0 26.6 5.1 6.1 2.3 17.2 2.2 7.3 4.2 20.8 0.2 3.7 0.0 3.5 3.6 18.2 1.8 1.9 1.2 0.4 2.8 4.6 9.7 3.6 3.1 1.5 1.3 4.2 1.8 27.8 25.7 20.2 4.6 2.4 0.0 21.5 1.0 19.5 4.1 8.0 0.0 5.6 2.0 2.2 0.0 8.0 6.9 3.8 3.6 3.4 3.0 2.6 3.9 4.6 4.3 6.0 6.6 3.7 1.4 0.3 0.3 1.2 0.3 4.4 0.6 5.8 1.3 1.6 SLC5A12 "MGC52019, SMCT2" ENSG00000148942 "Solute carrier family 5 member 12" Q1EHB4 11 26667020-26723427 "Metabolic proteins, Predicted membrane proteins, Transporters" "Ion transport, Sodium transport, Symport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "epididymis: 47.7;intestine: 30.1;kidney: 171.7" "Group enriched" "Detected in some" 23 "Proximal enterocytes: 286.0;Proximal tubular cells: 181.0" "Cancer enriched" "Detected in single" 26 "renal cancer: 9.0" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 2.3;NTERA-2: 1.7;SuSa: 3.3;T-47d: 1.2" "Not detected" "Not detected" "Not detected" "Not detected" HPA060904 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 7: Kidney - Transmembrane transport" "Cluster 5: NTERA-2 - Transcription" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" Nucleoplasm "HPA060904: AB_2684385" "unprognostic (3.69e-3)" "unprognostic (6.92e-2)" "unprognostic (1.79e-1)" "unprognostic (2.86e-1)" "unprognostic (2.01e-2)" "unprognostic (9.35e-3)" "unprognostic (4.21e-3)" "unprognostic (4.49e-2)" "unprognostic (2.36e-3)" "unprognostic (1.71e-1)" "unprognostic (2.03e-2)" "unprognostic (3.43e-1)" "unprognostic (2.91e-3)" "unprognostic (1.34e-1)" "unprognostic (8.53e-2)" "unprognostic (1.42e-2)" "unprognostic (9.40e-3)" 0.1 0.1 0.3 0.0 0.5 0.9 0.1 0.9 0.4 0.0 0.3 0.2 4.9 0.1 47.7 0.0 0.1 0.1 4.3 0.3 0.4 171.7 1.7 0.1 0.1 0.2 0.1 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.2 1.0 0.1 0.1 0.1 0.3 30.1 0.0 0.0 0.6 0.3 0.2 0.2 0.1 0.1 0.1 0.0 0.1 0.0 0.5 0.2 0.0 0.1 0.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.1 0.2 0.3 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 2.3 0.0 0.0 0.1 0.2 1.7 0.3 0.0 0.0 0.0 0.3 0.0 0.5 0.8 0.1 0.7 0.1 0.0 3.3 1.2 0.2 0.2 0.2 0.1 0.2 0.1 1.0 0.3 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.5 0.9 0.4 0.3 0.4 0.2 0.1 0.2 0.0 0.2 0.5 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.3 0.0 0.1 3.7 0.0 0.1 0.0 2.4 9.8 0.0 1.4 0.2 0.0 0.2 0.0 0.0 0.7 0.0 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.3 6.7 0.0 0.0 0.0 0.2 0.0 0.7 0.0 1.0 0.0 0.8 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 286.0 181.0 0.1 0.3 0.0 0.0 0.1 0.1 0.3 0.0 0.0 0.1 0.6 4.5 3.5 0.1 SLC7A2 "ATRC2, CAT-2, HCAT2" ENSG00000003989 "Solute carrier family 7 member 2" P52569 8 17497088-17570573 "Metabolic proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "liver: 176.7;parathyroid gland: 224.1" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 93.1;Glandular and luminal cells: 139.8;Hepatocytes: 249.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "HHSteC: 204.3;RT4: 55.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA009277 Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 8: Non-specific - Mitochondria" "Cluster 30: Epithelial cell lines - Translation" "Cluster 44: Endometrium - Transcription" "Plasma membrane" "Cell Junctions" "HPA009277: AB_2668229" "unprognostic (1.31e-1)" "unprognostic (2.28e-1)" "unprognostic (1.07e-1)" "unprognostic (1.13e-2)" "unprognostic (1.06e-1)" "unprognostic (5.20e-2)" "unprognostic (7.24e-3)" "unprognostic (3.11e-1)" "unprognostic (1.76e-1)" "unprognostic (4.49e-1)" "unprognostic (1.34e-2)" "unprognostic (1.11e-2)" "prognostic unfavorable (2.65e-7)" "prognostic unfavorable (3.08e-4)" "unprognostic (1.46e-2)" "unprognostic (8.98e-2)" "unprognostic (1.79e-1)" 28.6 11.6 7.9 3.4 7.0 0.2 17.2 9.5 9.6 32.5 16.6 6.2 2.4 15.2 17.8 11.3 42.5 11.2 12.2 10.0 8.0 8.0 176.7 7.5 2.7 14.1 6.2 84.4 83.1 224.1 7.1 9.8 12.6 14.2 4.3 17.6 5.1 7.2 114.5 8.1 4.5 13.4 12.7 3.8 8.3 15.4 7.1 3.1 45.1 45.8 3.5 10.5 14.9 15.9 0.0 3.1 1.0 32.4 0.2 0.3 35.1 0.3 22.1 1.7 2.0 10.7 0.1 0.0 7.4 0.0 4.7 0.0 23.5 5.4 7.4 0.0 12.3 0.0 24.8 23.2 204.3 10.3 0.0 27.7 4.5 27.2 25.7 0.0 10.2 0.0 0.2 0.0 24.9 35.5 1.3 11.7 11.8 7.4 2.9 0.0 16.2 17.6 2.7 55.3 0.4 4.3 1.7 0.8 9.9 23.5 0.0 1.2 22.9 0.0 11.8 0.1 0.1 0.0 0.0 0.1 0.0 0.0 2.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 7.9 7.0 9.5 9.6 10.0 8.0 14.1 6.2 12.6 12.7 7.1 15.9 9.4 12.8 78.1 58.8 0.4 8.3 6.6 5.8 20.5 2.9 52.0 25.8 15.5 38.6 16.3 7.3 35.5 22.6 0.1 0.4 0.0 8.3 12.8 67.0 40.4 5.6 87.9 10.7 0.5 93.1 15.1 20.6 0.5 139.8 2.5 0.4 7.1 249.0 5.8 0.0 19.9 3.6 0.0 6.7 2.3 22.9 37.9 1.4 3.6 1.9 0.6 23.5 0.0 11.6 2.6 20.5 0.6 27.8 0.1 50.2 0.3 3.7 53.9 38.0 59.2 8.8 75.7 0.3 1.1 7.8 3.8 26.0 1.6 9.5 3.2 8.4 SLC7A6 "KIAA0245, LAT-2, LAT3, y+LAT-2" ENSG00000103064 "Solute carrier family 7 member 6" Q92536 16 68264516-68301823 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Amino-acid transport, Antiport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 75.0" "Cell type enhanced" "Detected in many" "Microglial cells: 55.3;Syncytiotrophoblasts: 47.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA050713 Uncertain Uncertain "Vesicles,Plasma membrane" NA NA "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 39: CACO-2 - Unknown function" "Cluster 63: NK-cells & T-cells - Immune response" Vesicles "Plasma membrane" "HPA050713: AB_2681218" "unprognostic (6.35e-2)" "unprognostic (4.63e-2)" "unprognostic (1.41e-1)" "unprognostic (1.40e-2)" "unprognostic (2.41e-1)" "unprognostic (5.02e-2)" "unprognostic (1.24e-3)" "unprognostic (1.16e-1)" "unprognostic (1.48e-1)" "unprognostic (5.16e-2)" "unprognostic (1.11e-1)" "unprognostic (2.76e-2)" "unprognostic (1.89e-3)" "unprognostic (7.82e-2)" "unprognostic (2.66e-1)" "unprognostic (4.79e-3)" "prognostic unfavorable (1.84e-4)" 35.3 8.8 1.7 15.5 1.9 8.4 26.9 6.5 3.3 5.5 17.3 8.3 3.9 5.8 11.5 4.5 8.6 4.4 18.5 3.3 2.2 5.9 2.0 10.9 18.6 1.0 1.3 2.7 3.8 2.5 9.6 18.6 1.5 6.2 11.1 5.0 7.3 5.2 75.0 10.2 12.0 7.7 1.0 10.7 6.6 5.1 2.2 37.6 16.7 26.9 21.5 6.8 4.8 1.1 22.6 22.1 16.3 16.8 46.9 27.6 42.9 24.9 18.7 36.9 30.6 97.9 16.2 43.7 19.8 33.4 10.9 33.1 32.0 32.2 39.7 9.5 22.9 23.8 47.3 31.0 7.7 28.2 20.3 19.3 26.1 27.5 13.5 11.4 25.3 21.0 35.1 7.3 20.5 11.7 36.4 19.3 12.4 14.6 8.1 45.0 10.2 36.0 12.0 19.6 23.7 13.5 75.7 20.8 6.8 13.4 30.9 13.3 38.4 24.6 19.0 20.5 32.8 16.7 33.5 50.3 15.6 20.1 17.2 3.4 3.2 2.8 4.3 1.7 5.4 6.8 6.6 4.3 3.6 6.3 11.7 6.7 6.1 7.1 1.4 16.8 3.1 1.5 1.7 1.9 6.5 3.3 3.3 2.2 1.0 1.3 1.5 1.0 2.2 1.1 8.5 41.7 18.8 12.4 18.4 19.6 9.3 8.5 13.6 6.1 5.9 4.8 19.9 2.8 4.9 18.4 37.5 25.1 23.3 7.3 0.0 3.3 5.5 10.7 16.8 12.0 2.4 2.1 39.3 4.0 2.5 12.8 4.1 3.3 4.5 1.8 6.8 1.4 14.6 10.1 40.3 10.5 4.1 8.5 12.1 18.3 5.9 9.9 10.6 55.3 10.0 1.8 14.4 13.0 10.7 5.6 5.9 3.8 16.0 8.0 2.5 0.6 10.4 2.7 0.0 10.8 7.2 17.3 10.9 6.7 21.9 47.9 23.5 4.3 7.8 2.6 SLC8A1 NCX1 ENSG00000183023 "Solute carrier family 8 member A1" P32418 2 40097270-40611053 "FDA approved drug targets, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Calcium transport, Ion transport, Sodium transport, Transport" Calmodulin-binding "FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 117.5" "Group enriched" "Detected in many" 8 "Cardiomyocytes: 743.1;Excitatory neurons: 1267.5;Inhibitory neurons: 631.3;Microglial cells: 574.3;Oligodendrocyte precursor cells: 753.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 44.2" "Group enriched" "Detected in many" 6 "granulocytes: 44.2;monocytes: 11.5" "Cell line enhanced" "Detected in many" "BJ: 28.9;fHDF/TERT166: 70.4;hTERT-HME1: 19.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022694, HPA070007" Uncertain Supported "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 44: Heart - Cardiac muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Nucleoplasm, Plasma membrane" "CAB022694: , HPA070007: AB_2686227" "unprognostic (2.46e-1)" "unprognostic (1.33e-2)" "unprognostic (1.42e-2)" "unprognostic (7.57e-6)" "unprognostic (1.56e-1)" "unprognostic (3.94e-1)" "unprognostic (2.28e-2)" "unprognostic (4.60e-2)" "unprognostic (1.31e-1)" "unprognostic (7.71e-2)" "unprognostic (1.21e-2)" "unprognostic (1.07e-1)" "unprognostic (3.66e-2)" "unprognostic (7.04e-3)" "unprognostic (3.93e-2)" "unprognostic (5.46e-2)" "unprognostic (6.77e-2)" 6.1 4.0 25.7 7.2 25.8 2.0 1.6 0.0 28.0 4.7 0.0 9.6 5.0 19.7 5.6 5.9 5.6 6.5 117.5 30.6 11.0 17.5 3.1 5.8 3.3 1.5 19.8 2.5 1.8 0.7 0.8 11.2 0.7 18.8 4.8 5.9 1.0 27.1 0.3 1.5 5.5 23.4 2.7 7.3 3.5 0.7 19.5 2.0 0.8 0.9 1.5 8.9 2.5 24.1 3.0 2.2 2.1 0.2 3.1 6.4 0.0 28.9 11.1 9.4 6.1 0.0 4.7 0.1 2.2 70.4 10.1 1.1 0.5 4.8 9.5 0.0 3.9 0.0 0.0 0.0 0.1 0.0 0.5 3.7 0.0 10.8 19.8 4.3 0.7 0.0 0.0 0.4 12.1 0.0 0.9 0.1 1.4 0.3 4.0 7.8 14.8 0.0 3.3 0.4 3.2 0.6 0.0 0.0 0.0 9.7 0.1 0.6 9.8 8.8 0.3 0.0 3.1 1.6 0.0 0.0 1.4 1.7 1.4 0.0 8.3 0.0 0.0 9.1 0.0 0.0 0.0 0.0 4.5 0.0 0.0 0.0 44.2 0.0 11.5 0.3 0.0 1.1 25.7 25.8 0.0 28.0 30.6 11.0 1.5 19.8 0.7 2.7 19.5 24.1 10.3 3.2 2.8 39.5 3.6 1.3 0.0 0.2 1.2 79.1 0.5 5.8 743.1 2.8 0.6 35.0 4.2 0.5 0.3 0.0 0.0 0.0 1.1 2.3 52.8 15.1 0.0 3.0 1267.5 0.0 1.6 26.6 1.5 3.0 0.0 0.2 12.1 0.3 29.3 0.0 631.3 2.5 0.0 78.0 26.7 1.4 0.0 88.8 1.8 574.3 42.7 32.0 1.0 753.0 20.5 0.1 3.8 8.2 0.7 0.2 24.7 0.5 0.0 7.2 13.1 1.4 46.6 0.2 1.2 0.5 3.1 1.1 1.2 0.7 2.5 0.1 SLC9A4 NHE4 ENSG00000180251 "Solute carrier family 9 member A4" Q6AI14 2 102473226-102533972 "Metabolic proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "stomach 1: 53.8" "Group enriched" "Detected in some" 12 "Collecting duct cells: 25.8;Gastric mucus-secreting cells: 54.0" "Cancer enhanced" "Detected in some" "urothelial cancer: 2.1" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HDLM-2: 2.3;OE19: 6.8;RT4: 4.1" "Group enriched" "Detected in some" 18 "hippocampal formation: 10.6;olfactory bulb: 6.8" "Low region specificity" "Detected in single" HPA036096 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 4: Stomach - Digestion" "Cluster 21: OE19 - Mitochondria" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Nucleoplasm, Plasma membrane" "HPA036096: AB_2674939" "unprognostic (1.41e-1)" "unprognostic (3.76e-2)" "unprognostic (9.31e-2)" "unprognostic (3.09e-3)" "unprognostic (7.58e-2)" "unprognostic (1.46e-1)" "unprognostic (7.17e-2)" "unprognostic (5.35e-1)" "unprognostic (9.44e-3)" "unprognostic (3.26e-2)" "unprognostic (1.30e-1)" "unprognostic (2.46e-2)" "unprognostic (3.12e-1)" "unprognostic (5.04e-1)" "unprognostic (2.50e-1)" "unprognostic (1.98e-2)" 0.0 0.0 0.4 0.1 0.5 0.8 0.2 0.7 0.7 0.3 0.0 0.0 2.0 0.1 0.1 1.5 0.1 1.2 0.6 0.4 0.4 8.6 0.0 0.0 0.4 0.1 0.1 0.1 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.4 1.3 0.5 1.4 0.4 0.0 0.0 0.0 0.2 53.8 0.3 0.2 0.1 0.1 0.0 0.5 0.4 0.1 0.6 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.2 0.0 1.3 0.0 0.1 0.1 0.0 0.0 0.0 2.3 0.1 0.1 0.2 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.0 0.2 0.0 0.0 0.5 6.8 0.2 0.0 0.2 0.1 0.0 4.1 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.1 0.1 0.2 0.5 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.4 0.5 0.7 0.7 0.4 0.4 0.1 0.1 0.2 0.0 0.2 0.6 0.0 3.2 3.2 0.0 0.1 0.0 0.0 0.2 0.0 0.0 1.0 0.0 0.4 0.0 0.9 25.8 0.0 0.1 0.0 0.0 0.0 0.0 2.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.6 54.0 0.6 1.3 0.0 0.0 0.0 0.0 0.0 0.2 0.3 2.0 0.0 0.0 0.2 0.0 0.3 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.1 1.8 0.0 0.0 0.0 0.0 0.6 0.8 0.0 0.0 0.1 0.4 0.0 0.3 0.3 SLC9A5 NHE5 ENSG00000135740 "Solute carrier family 9 member A5" Q14940 16 67237683-67272191 "Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 6.6;lymphoid tissue: 17.4" "Cell type enhanced" "Detected in some" "Excitatory neurons: 11.1;Horizontal cells: 16.8;Inhibitory neurons: 12.2;Oligodendrocyte precursor cells: 7.1;Spermatocytes: 17.2;Theca cells: 6.8" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "U-138 MG: 6.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" "HPA041004, HPA041329" Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 32: Brain & Lymphoid tissue - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 13: Spermatocytes & Spermatogonia - Spermatogenesis" Cytosol "Plasma membrane" "HPA041004: AB_10794433, HPA041329: AB_10794373" "unprognostic (8.90e-2)" "unprognostic (9.70e-2)" "unprognostic (3.39e-3)" "unprognostic (1.37e-1)" "unprognostic (1.44e-1)" "unprognostic (1.43e-1)" "unprognostic (2.24e-2)" "unprognostic (5.17e-2)" "unprognostic (1.50e-1)" "unprognostic (1.12e-1)" "unprognostic (2.50e-3)" "unprognostic (4.84e-2)" "unprognostic (9.85e-11)" "unprognostic (9.21e-2)" "unprognostic (1.95e-1)" "unprognostic (8.12e-3)" "unprognostic (9.07e-2)" 0.9 0.6 4.2 0.3 6.6 0.1 1.0 5.4 6.5 0.8 2.5 0.5 0.4 0.4 1.0 0.2 0.5 0.6 1.6 4.6 3.9 0.8 0.2 1.4 0.8 4.8 4.1 1.2 0.6 0.1 0.8 0.6 5.3 0.9 0.3 1.2 0.8 0.3 1.8 1.5 0.5 0.1 3.4 17.4 0.5 3.2 4.2 0.1 0.8 0.7 0.4 0.4 0.5 4.0 0.3 2.9 2.6 0.9 4.7 3.2 0.3 1.1 4.1 2.4 2.2 0.1 2.0 0.0 0.6 1.2 1.2 0.1 0.6 0.4 1.0 0.8 0.8 2.1 0.5 0.7 0.5 1.0 4.7 3.8 1.0 1.5 0.2 4.5 1.0 0.9 0.5 1.3 1.6 1.7 0.0 0.2 1.5 0.2 0.2 0.0 0.5 0.7 0.4 0.5 1.6 0.9 2.4 0.1 1.2 0.6 1.1 0.2 0.8 6.4 0.9 1.1 0.4 2.4 0.5 1.3 4.5 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 4.2 6.6 5.4 6.5 4.6 3.9 4.8 4.1 5.3 3.4 4.2 4.0 0.6 3.2 2.8 4.2 0.4 0.6 0.2 0.1 1.2 3.4 1.8 1.3 1.5 1.5 0.2 0.0 0.0 0.3 0.1 0.5 0.0 0.3 1.8 0.2 0.8 0.8 1.2 0.0 11.1 0.2 0.1 0.7 0.0 0.9 0.0 0.9 1.4 0.0 0.1 16.8 12.2 0.3 0.0 0.0 0.4 0.7 0.3 0.5 0.0 1.9 0.6 0.3 0.0 7.1 2.6 0.5 0.1 2.2 0.0 0.5 0.2 0.0 0.7 0.9 0.0 0.6 1.4 17.2 4.6 0.3 0.9 0.0 0.3 6.8 0.3 0.2 SLC9C2 "MGC43026, SLC9A11" ENSG00000162753 "Solute carrier family 9 member C2 (putative)" Q5TAH2 1 173500460-173603072 "Predicted membrane proteins, Transporters" "Antiport, Ion transport, Sodium transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 1.3;choroid plexus: 1.9;testis: 6.0" "Cell type enriched" "Detected in some" 4 "Astrocytes: 27.1" "Not detected" "Not detected" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA059122, HPA079529" Enhanced Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 49: Ciliated cells - Cilium organization" "Cluster 64: Astrocytes - Nervous system maintenance" "Plasma membrane" "Nuclear speckles" "HPA059122: , HPA079529: " "unprognostic (2.10e-1)" "unprognostic (2.69e-1)" "unprognostic (8.52e-2)" "unprognostic (5.88e-3)" "unprognostic (3.24e-2)" "unprognostic (2.21e-1)" "unprognostic (1.29e-3)" "unprognostic (1.19e-1)" "unprognostic (4.21e-2)" "unprognostic (4.92e-1)" "unprognostic (1.88e-1)" "unprognostic (1.18e-6)" "unprognostic (1.66e-1)" "unprognostic (1.01e-2)" "unprognostic (2.98e-1)" "unprognostic (1.81e-1)" 0.0 0.0 0.4 0.0 0.5 0.0 0.0 0.2 0.2 0.0 1.9 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 1.3 1.2 0.2 0.0 0.0 0.1 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.2 0.1 6.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 0.5 0.2 0.2 0.5 0.3 1.3 1.2 0.8 0.8 0.4 0.6 0.0 0.0 0.0 27.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 1.6 0.0 1.3 0.0 6.2 0.1 1.3 0.1 0.0 0.1 6.2 1.7 0.1 0.4 0.0 0.0 5.0 0.0 0.5 0.3 0.0 0.1 0.0 0.5 0.4 1.0 0.0 0.0 3.8 0.0 0.0 0.0 0.0 4.0 0.0 0.0 0.0 4.7 0.0 0.7 0.0 1.5 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 3.1 0.1 0.0 0.1 0.1 5.4 0.4 0.0 0.0 0.1 0.0 1.3 0.0 0.0 SLCO5A1 "OATP-J, OATP5A1, OATPRP4, SLC21A15" ENSG00000137571 "Solute carrier organic anion transporter family member 5A1" Q9H2Y9 8 69667046-69834978 "Predicted membrane proteins, Transporters" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "lymphoid tissue: 6.5;skeletal muscle: 7.6;tongue: 11.1" "Group enriched" "Detected in many" 4 "Bipolar cells: 10.1;Cardiomyocytes: 14.4;Enteroendocrine cells: 15.6;Excitatory neurons: 8.6;Inhibitory neurons: 30.1;monocytes: 21.2;Oligodendrocyte precursor cells: 26.2;Plasma cells: 14.3;Prostatic glandular cells: 11.8" "Cancer enhanced" "Detected in some" "prostate cancer: 1.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "HAP1: 5.5;NTERA-2: 3.7;RPMI-8226: 3.6;SCLC-21H: 3.9;U-266/70: 2.1" "Group enriched" "Detected in some" 7 "basal ganglia: 2.3;olfactory bulb: 6.7" "Region enriched" "Detected in some" 7 "olfactory bulb: 12.8" HPA025062 Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Vesicles "HPA025062: AB_1857220" "unprognostic (1.30e-3)" "unprognostic (7.35e-3)" "unprognostic (4.13e-2)" "unprognostic (1.14e-2)" "unprognostic (1.48e-1)" "unprognostic (5.70e-2)" "unprognostic (1.46e-2)" "unprognostic (1.51e-1)" "unprognostic (2.37e-4)" "unprognostic (1.75e-1)" "unprognostic (4.48e-4)" "unprognostic (1.74e-2)" "unprognostic (2.92e-6)" "unprognostic (2.20e-1)" "unprognostic (1.23e-1)" "unprognostic (2.13e-1)" "unprognostic (4.50e-2)" 0.1 0.0 0.3 0.9 0.4 0.9 0.1 0.0 0.4 0.2 0.0 0.2 0.2 0.2 0.0 0.5 0.3 0.2 3.7 0.2 0.6 0.0 0.0 0.1 1.0 0.2 0.0 0.0 0.4 0.0 1.5 0.0 0.2 2.3 0.4 0.7 0.3 0.0 7.6 0.1 0.3 0.1 0.0 0.5 0.2 0.3 0.1 6.5 0.0 11.1 0.9 0.6 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.2 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.5 0.0 0.0 1.5 1.8 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.7 3.7 0.0 0.6 0.6 0.6 3.6 0.0 0.0 3.9 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.7 2.1 0.3 0.0 0.2 0.0 1.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.4 0.2 0.6 0.2 0.0 0.2 0.0 0.1 0.1 0.1 3.2 0.0 3.6 3.6 0.3 1.8 0.0 0.6 10.1 0.2 0.3 14.4 0.0 0.6 0.0 2.1 0.0 0.0 0.6 0.0 1.8 0.6 0.4 1.7 2.0 15.6 0.0 8.6 1.3 0.0 4.0 0.0 1.7 0.0 0.0 0.0 0.2 0.1 1.7 30.1 2.0 0.0 0.0 3.6 0.6 0.0 0.7 0.0 3.7 21.2 0.5 0.0 26.2 2.2 2.1 0.1 0.0 14.3 11.8 0.0 0.1 0.0 0.3 0.0 3.4 2.0 1.1 2.6 0.4 0.4 0.0 0.1 0.4 1.5 1.5 SLK "KIAA0204, se20-9, STK2" ENSG00000065613 "STE20 like kinase" Q9H2G2 10 103967140-104029233 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Urothelial cells: 201.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA015757 Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 49: Eosinophils - Unknown function" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA015757: AB_1857236" "unprognostic (1.89e-1)" "unprognostic (1.80e-1)" "unprognostic (1.38e-1)" "unprognostic (8.28e-2)" "unprognostic (1.01e-1)" "unprognostic (3.64e-1)" "unprognostic (8.67e-2)" "unprognostic (6.85e-2)" "unprognostic (1.01e-1)" "unprognostic (2.31e-1)" "prognostic unfavorable (2.77e-5)" "unprognostic (1.95e-1)" "prognostic favorable (3.95e-5)" "unprognostic (8.48e-2)" "unprognostic (3.95e-1)" "unprognostic (3.09e-2)" "unprognostic (1.07e-1)" 20.5 15.1 10.9 15.2 19.9 28.9 21.7 20.9 13.7 19.9 15.3 20.4 13.3 21.3 16.2 56.4 14.1 21.3 22.4 11.7 10.0 20.6 17.8 24.0 11.8 11.5 11.1 24.0 16.7 26.3 9.6 25.8 11.7 17.6 20.8 15.1 21.9 17.7 23.1 26.3 14.7 20.6 10.3 14.9 24.1 15.2 12.3 15.2 22.4 25.1 17.5 30.5 28.6 18.5 50.5 28.9 33.7 24.3 36.6 50.1 14.2 30.6 40.7 22.5 20.9 18.4 53.7 26.6 18.6 31.8 19.1 53.7 18.0 39.5 33.5 21.3 24.7 27.0 23.5 15.6 26.6 32.7 22.4 25.5 49.5 30.9 87.6 31.7 40.9 16.9 34.6 17.9 29.8 18.6 23.0 18.0 8.4 32.4 18.2 22.2 41.4 13.8 29.0 60.3 8.0 13.8 26.6 25.7 25.8 17.2 13.8 23.4 63.4 16.6 16.9 30.6 36.3 21.6 28.0 16.7 24.2 43.1 10.7 0.6 0.5 1.7 1.4 0.5 1.5 0.4 0.8 1.0 0.5 0.6 0.6 1.0 2.7 0.5 0.4 0.9 0.8 0.3 10.9 19.9 20.9 13.7 11.7 10.0 11.5 11.1 11.7 10.3 12.3 18.5 73.5 179.5 129.5 38.5 19.9 57.0 87.1 30.9 26.7 32.2 32.0 35.1 110.4 30.0 100.9 44.1 25.0 37.4 40.1 70.0 3.9 34.0 8.4 43.3 77.1 80.2 18.5 25.5 35.3 54.0 13.6 52.6 44.9 90.3 35.3 54.6 50.7 25.3 19.9 25.2 39.3 37.2 18.3 24.5 36.9 16.6 46.6 37.5 8.8 34.7 43.9 25.7 27.8 34.2 63.9 85.5 81.6 63.2 22.3 67.8 21.9 11.5 57.9 25.4 6.6 68.1 49.3 46.3 35.3 61.4 68.5 52.4 44.2 71.7 37.4 201.0 SMCO3 "C12orf69, LOC440087" ENSG00000179256 "Single-pass membrane protein with coiled-coil domains 3" A2RU48 12 14804650-14814182 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "cervix: 3.4;kidney: 3.0" "Cell type enhanced" "Detected in some" "Cholangiocytes: 2.8;Collecting duct cells: 1.8;Distal tubular cells: 5.9;Erythroid cells: 2.7;Hepatic stellate cells: 4.6;Proximal tubular cells: 7.3" "Cancer enhanced" "Detected in some" "prostate cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "AN3-CA: 1.9" "Low region specificity" "Detected in all" "Region enriched" "Detected in single" 7 "spinal cord: 3.6" "HPA040574, HPA047804" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 81: Kidney & Liver - Metabolism" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane, Cytosol" "HPA040574: AB_2677026, HPA047804: AB_2680160" "unprognostic (1.16e-1)" "unprognostic (2.09e-4)" "unprognostic (2.40e-4)" "unprognostic (5.10e-2)" "unprognostic (3.88e-2)" "unprognostic (6.45e-2)" "unprognostic (4.43e-2)" "unprognostic (2.86e-2)" "unprognostic (1.52e-1)" "unprognostic (1.32e-1)" "unprognostic (7.31e-2)" "unprognostic (3.66e-2)" "unprognostic (1.48e-8)" "unprognostic (2.85e-1)" "unprognostic (7.53e-3)" "unprognostic (2.05e-1)" "unprognostic (1.38e-1)" 0.5 0.4 0.0 0.1 0.2 0.3 0.2 0.1 0.1 3.4 0.3 0.2 0.0 0.3 0.1 0.0 0.3 1.8 0.9 0.1 0.2 3.0 1.5 1.1 0.5 0.1 0.2 0.2 0.2 0.5 0.2 1.1 0.1 0.8 0.1 1.3 0.1 1.6 0.1 0.1 0.1 0.1 0.1 1.8 0.1 0.2 0.1 0.0 0.8 0.0 0.1 0.1 0.6 0.3 0.0 0.0 0.1 1.9 0.2 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.6 0.0 0.0 0.4 0.0 0.0 0.1 0.1 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.4 0.1 0.0 0.1 0.2 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.1 0.2 0.1 0.2 0.1 0.1 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.2 0.1 0.5 2.8 0.0 1.8 0.0 0.1 0.0 0.0 5.9 0.2 0.0 0.0 0.2 0.3 0.0 2.7 0.1 0.2 0.3 0.2 0.0 0.0 0.0 0.0 4.6 0.2 0.1 0.0 0.1 0.0 0.0 0.3 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.2 0.0 7.3 0.0 0.9 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.0 0.0 SNAP25 "bA416N4.2, dJ1068F16.2, RIC-4, RIC4, SEC9, SNAP, SNAP-25" ENSG00000132639 "Synaptosome associated protein 25" P60880 20 10218830-10307418 "Disease related genes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Transporters" "Congenital myasthenic syndrome, Disease variant, FDA approved drug targets, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 20 "brain: 1658.7;retina: 492.0" "Cell type enhanced" "Detected in many" "Bipolar cells: 559.2;Excitatory neurons: 1015.8;Inhibitory neurons: 552.8;Rod photoreceptor cells: 254.4" "Cancer enriched" "Detected in many" 4 "glioma: 28.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Karpas-707: 23.8;SCLC-21H: 78.2;SH-SY5Y: 46.6;U-87 MG: 56.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB000360, HPA001830, HPA071013" Enhanced Supported Approved "Vesicles,Plasma membrane" NA NA 9000 "Cluster 6: Brain - Smell perception" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Vesicles "CAB000360: AB_2286342, HPA001830: AB_1080039, HPA071013: " "unprognostic (1.64e-3)" "unprognostic (7.26e-3)" "unprognostic (4.36e-2)" "unprognostic (2.49e-7)" "unprognostic (6.86e-3)" "unprognostic (5.87e-3)" "unprognostic (1.15e-2)" "unprognostic (9.94e-2)" "unprognostic (3.13e-1)" "unprognostic (5.82e-3)" "unprognostic (4.80e-3)" "unprognostic (8.06e-2)" "unprognostic (1.09e-1)" "unprognostic (6.18e-3)" "unprognostic (2.48e-1)" "unprognostic (6.28e-3)" "unprognostic (1.02e-2)" 1.5 43.6 251.0 4.1 383.5 0.2 4.4 598.0 1658.7 0.8 0.0 5.7 3.7 7.9 12.9 0.5 7.7 2.3 3.2 420.4 142.2 1.4 1.0 1.8 0.4 427.4 24.7 6.9 6.3 1.2 54.3 0.6 386.6 3.2 2.3 492.0 0.5 19.6 0.8 0.7 3.9 8.1 38.1 0.2 6.3 3.6 147.6 0.5 0.7 0.1 0.4 1.1 1.6 726.9 0.0 4.7 3.9 0.0 0.4 0.1 0.0 2.0 0.0 4.8 1.4 0.0 0.0 0.0 4.3 0.0 3.4 0.8 0.6 0.0 9.6 0.5 0.3 0.0 6.8 0.7 3.5 0.0 0.5 4.4 0.0 3.9 0.0 10.7 0.0 2.8 0.0 23.8 1.6 0.0 0.0 0.0 0.8 3.0 0.0 0.0 0.0 0.1 0.9 0.0 78.2 46.6 0.7 0.1 0.0 2.4 0.0 6.5 0.0 5.0 6.8 0.0 2.3 0.1 12.9 0.1 56.0 0.0 4.7 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 251.0 383.5 598.0 1658.7 420.4 142.2 427.4 24.7 386.6 38.1 147.6 726.9 0.5 0.0 0.0 117.2 0.0 0.8 1.4 0.1 0.0 559.2 0.2 1.3 0.5 8.6 0.0 0.0 106.3 0.0 0.2 0.0 0.0 0.2 16.3 0.1 0.7 5.2 43.5 0.0 1015.8 0.0 0.1 3.9 0.0 0.2 0.0 0.6 0.0 0.2 0.1 65.6 552.8 3.4 0.0 0.0 0.4 83.3 17.1 0.1 1.8 120.9 0.0 71.9 0.0 179.4 113.3 1.0 2.6 68.8 0.0 0.6 0.1 3.0 0.0 254.4 0.0 0.0 1.3 1.1 0.4 0.0 0.9 0.0 0.0 2.6 0.1 0.1 SNTG2 "G2SYN, SYN5" ENSG00000172554 "Syntrophin gamma 2" Q9NY99 2 950849-1367613 "Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Early spermatids: 68.2;Excitatory neurons: 24.4;Horizontal cells: 90.9;Late spermatids: 44.7;Spermatocytes: 22.0" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Daudi: 1.6;HAP1: 1.7;JURKAT: 1.6;MOLT-4: 1.1;NTERA-2: 2.0;SCLC-21H: 2.0" "Low region specificity" "Detected in many" "HPA065258, HPA077904" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 77: Retina - Visual perception" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 29: Early spermatids - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA065258: , HPA077904: " "unprognostic (7.52e-3)" "unprognostic (7.52e-4)" "unprognostic (4.15e-1)" "unprognostic (3.50e-2)" "unprognostic (2.52e-2)" "unprognostic (1.39e-3)" "unprognostic (2.46e-3)" "unprognostic (2.05e-1)" "unprognostic (2.23e-1)" "unprognostic (3.26e-2)" "unprognostic (7.87e-3)" "unprognostic (3.58e-3)" "unprognostic (3.64e-1)" "unprognostic (2.52e-1)" "unprognostic (1.77e-2)" "unprognostic (5.05e-2)" 2.0 0.3 0.6 0.0 0.7 0.0 1.8 1.0 0.6 1.0 1.1 0.5 0.1 1.2 0.2 0.5 1.2 0.2 0.4 1.7 0.7 0.1 0.0 0.3 0.0 1.7 0.9 0.2 0.9 0.0 2.9 0.0 1.3 0.6 0.2 2.1 0.5 0.0 0.4 1.1 0.6 0.7 0.4 3.2 0.3 1.8 0.7 0.2 0.7 0.9 0.1 0.8 1.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 1.1 0.0 2.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 1.0 0.6 1.7 0.7 1.7 0.9 1.3 0.4 0.7 0.6 6.8 0.0 0.0 0.7 0.4 0.9 0.1 0.0 0.6 0.8 0.2 0.3 0.7 0.0 0.0 1.8 0.0 0.0 0.0 0.1 0.0 0.0 68.2 0.1 0.9 7.3 0.0 0.0 24.4 0.2 0.5 0.8 0.0 0.0 0.0 3.0 0.0 0.0 0.1 90.9 10.7 0.0 0.0 0.0 1.2 44.7 0.3 0.0 1.8 9.4 0.0 0.6 0.0 1.5 1.3 0.0 0.0 4.1 0.0 0.3 0.0 0.5 0.0 4.6 0.0 0.3 0.4 22.0 5.4 0.1 0.1 0.0 0.2 0.2 0.0 0.2 SNX9 "SDP1, SH3PX1, SH3PXD3A" ENSG00000130340 "Sorting nexin 9" Q9Y5X1 6 157700387-157945077 "Plasma proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Endocytosis, Mitosis, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Glandular and luminal cells: 251.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 10.0" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 146.6;GAMG: 145.8" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031410, HPA057203" Approved Supported "Plasma membrane,Cytosol" No No "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 46: Fibroblasts - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Cytosol "HPA031410: AB_10603339, HPA057203: AB_2683368" "unprognostic (1.63e-3)" "prognostic unfavorable (5.95e-4)" "unprognostic (1.39e-1)" "unprognostic (8.09e-2)" "unprognostic (8.09e-2)" "unprognostic (1.40e-2)" "unprognostic (4.06e-2)" "prognostic unfavorable (3.77e-4)" "unprognostic (7.93e-2)" "unprognostic (4.99e-3)" "unprognostic (4.45e-2)" "unprognostic (2.42e-1)" "prognostic favorable (9.95e-4)" "unprognostic (2.14e-1)" "unprognostic (2.46e-1)" "unprognostic (1.13e-2)" "unprognostic (2.57e-1)" 57.9 25.2 19.2 25.7 20.6 14.3 41.4 21.2 20.9 38.8 20.6 34.2 33.2 41.8 20.8 57.8 26.2 46.9 33.2 18.8 19.9 26.2 39.0 21.0 24.2 22.2 21.1 28.0 28.5 37.7 13.4 48.5 21.8 31.0 29.5 2.7 35.1 41.7 24.4 30.4 35.6 41.2 20.9 18.4 37.5 11.0 20.7 13.9 29.8 34.2 21.7 49.8 33.7 23.0 26.0 19.1 18.9 22.1 96.6 78.6 37.7 46.3 146.6 36.4 48.9 16.6 27.6 0.0 25.0 85.6 145.8 18.7 22.7 36.3 21.1 23.9 23.4 17.7 25.7 23.9 48.6 7.6 31.6 51.1 33.9 37.8 37.1 63.9 49.8 23.3 80.9 0.0 15.8 17.2 0.0 15.6 14.4 18.7 21.3 0.0 17.9 32.7 59.7 15.9 11.8 20.9 34.1 16.4 90.5 16.2 6.8 20.0 41.7 41.3 16.6 128.8 30.4 0.0 0.0 0.0 84.8 6.4 25.4 0.0 0.7 0.1 0.4 2.1 1.5 3.2 0.7 0.6 1.4 2.4 5.3 1.2 0.0 0.1 6.8 10.0 2.2 0.6 19.2 20.6 21.2 20.9 18.8 19.9 22.2 21.1 21.8 20.9 20.7 23.0 71.5 0.0 1.1 40.5 102.6 43.3 109.7 17.3 30.1 15.6 28.7 18.4 28.4 28.6 19.0 9.2 0.0 40.6 37.6 97.7 21.5 57.5 73.4 112.8 53.0 57.9 15.7 17.7 105.4 55.9 41.1 83.0 70.3 251.1 12.0 16.4 37.1 34.3 41.6 3.3 90.4 43.0 8.2 59.0 74.2 26.8 44.7 84.3 21.4 48.7 39.5 11.1 7.2 100.5 161.2 107.0 108.9 46.6 14.9 127.5 52.5 46.2 14.3 1.8 39.5 43.6 49.6 21.9 15.4 22.9 29.8 109.9 48.8 9.1 29.7 137.0 SOCS3 "CIS3, Cish3, SOCS-3, SSI-3" ENSG00000184557 "Suppressor of cytokine signaling 3" O14543 17 78356778-78360077 "Disease related genes, Predicted intracellular proteins" "Growth regulation, Ubl conjugation pathway" "Signal transduction inhibitor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 501.5" "Cell type enhanced" "Detected in many" "Adipocytes: 989.2;Endothelial cells: 635.9;Fibroblasts: 394.4;Langerhans cells: 381.5;Skeletal myocytes: 485.9;Smooth muscle cells: 381.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 9.5" "Group enriched" "Detected in many" 6 "granulocytes: 9.5;T-cells: 3.1" "Cell line enhanced" "Detected in many" "HDLM-2: 154.2;HSkMC: 73.3;U-266/70: 76.0" "Low region specificity" "Detected in many" "Region enriched" "Detected in many" 5 "spinal cord: 9.8" "CAB012220, HPA068569" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Cytosol "Plasma membrane" "CAB012220: AB_443287, HPA068569: AB_2686008" "prognostic favorable (4.80e-4)" "unprognostic (2.67e-1)" "unprognostic (5.05e-2)" "unprognostic (1.64e-3)" "unprognostic (4.41e-3)" "unprognostic (2.48e-3)" "unprognostic (1.81e-1)" "unprognostic (1.46e-1)" "unprognostic (6.88e-2)" "unprognostic (9.61e-3)" "unprognostic (1.84e-1)" "unprognostic (2.00e-2)" "prognostic unfavorable (9.34e-9)" "unprognostic (1.08e-2)" "unprognostic (8.80e-2)" "unprognostic (7.59e-3)" "unprognostic (8.40e-2)" 501.5 50.3 19.1 99.0 20.2 126.4 114.1 18.8 27.5 35.1 21.7 119.0 19.4 53.4 1.9 72.7 306.5 190.4 76.8 16.8 21.2 72.1 84.2 234.8 46.9 43.1 22.1 55.5 46.2 23.6 55.7 77.5 24.6 61.8 27.2 4.2 36.3 17.1 26.1 55.3 64.2 125.2 23.7 52.0 123.9 5.9 32.2 115.9 54.1 37.1 11.8 187.9 31.6 19.6 6.4 10.2 7.3 3.8 2.8 44.3 19.1 31.4 28.3 32.1 13.6 6.6 4.4 0.2 6.7 7.5 20.4 2.0 1.5 3.1 12.7 154.2 0.9 5.8 24.1 1.4 14.5 0.1 2.7 73.3 2.6 24.9 9.3 19.4 14.0 0.5 17.4 58.2 15.1 3.3 3.3 1.0 5.2 1.2 12.8 0.2 36.9 1.1 51.4 6.3 0.3 4.6 9.5 2.5 1.3 26.8 2.9 1.4 8.4 62.7 17.6 22.2 18.4 76.0 46.9 0.1 51.6 0.8 4.1 0.0 1.0 0.2 0.8 0.1 1.9 0.0 2.1 0.9 1.1 0.0 3.1 0.6 9.5 0.3 0.0 1.0 1.3 0.5 19.1 20.2 18.8 27.5 16.8 21.2 43.1 22.1 24.6 23.7 32.2 19.6 989.2 48.1 125.6 0.7 64.7 164.3 120.7 75.0 125.2 1.0 176.3 136.4 23.1 18.6 51.7 38.6 2.1 14.9 42.1 20.5 5.9 44.4 0.8 106.7 207.6 635.9 33.0 11.6 0.0 38.6 46.0 394.4 125.4 166.8 36.0 5.8 307.3 20.2 94.6 0.0 0.1 25.0 30.5 78.4 381.5 1.7 78.3 231.0 85.4 1.0 33.6 7.7 1.0 0.0 1.0 43.0 28.1 2.2 115.5 72.0 24.3 11.5 38.1 2.7 13.1 485.9 381.7 0.4 1.0 36.3 133.0 62.1 88.7 5.3 41.0 90.5 SORCS1 ENSG00000108018 "Sortilin related VPS10 domain containing receptor 1" Q8WY21 10 106573663-107164534 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.3;thyroid gland: 11.0" "Group enriched" "Detected in some" 7 "Excitatory neurons: 522.2;Inhibitory neurons: 179.7;Oligodendrocyte precursor cells: 381.5" "Cancer enhanced" "Detected in some" "melanoma: 3.2" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 12 "RH-30: 80.8;SH-SY5Y: 104.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA011948 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 58: Brain - Synaptic function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA011948: AB_1857366" "unprognostic (5.86e-3)" "unprognostic (8.45e-3)" "unprognostic (1.55e-2)" "unprognostic (1.67e-1)" "unprognostic (1.13e-1)" "unprognostic (1.36e-1)" "unprognostic (1.05e-2)" "unprognostic (2.92e-2)" "unprognostic (3.52e-2)" "unprognostic (5.58e-2)" "unprognostic (6.82e-3)" "unprognostic (5.81e-2)" "unprognostic (6.48e-4)" "unprognostic (2.51e-2)" "unprognostic (8.89e-3)" "unprognostic (2.22e-1)" "unprognostic (2.69e-4)" 0.6 3.1 3.0 1.9 6.2 0.0 1.3 0.0 10.3 2.5 0.0 9.4 0.7 1.1 0.3 0.9 1.6 1.1 3.1 5.4 5.8 4.7 0.1 0.1 1.0 0.6 4.5 0.7 1.6 0.0 0.9 0.0 2.7 2.2 1.9 9.6 1.1 2.5 0.3 1.5 3.6 1.4 0.5 0.8 2.5 1.2 5.8 1.0 11.0 1.7 1.5 3.6 2.8 6.6 0.0 0.0 3.2 0.0 0.0 0.0 0.0 0.9 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 1.6 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 1.6 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 80.8 0.1 0.0 0.0 0.0 104.9 0.0 0.0 3.3 0.3 0.0 0.0 0.0 0.0 0.6 6.1 0.0 0.0 0.0 0.0 0.0 0.0 7.9 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.0 6.2 0.0 10.3 5.4 5.8 0.6 4.5 2.7 0.5 5.8 6.6 0.0 0.0 0.5 7.2 0.0 0.6 0.0 0.0 1.2 2.0 0.1 0.5 2.6 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 1.1 16.6 0.1 4.9 0.2 0.0 0.0 522.2 0.0 0.0 3.6 0.0 0.1 0.0 1.0 0.0 0.0 0.2 1.7 179.7 0.0 0.0 0.3 0.3 5.2 0.0 0.2 1.8 26.2 0.0 49.1 0.0 381.5 10.0 0.1 0.0 0.4 0.0 0.0 0.0 2.2 0.0 2.1 0.0 1.0 0.3 0.2 1.9 0.2 0.1 0.0 0.3 0.0 0.0 0.0 SOX11 ENSG00000176887 "SRY-box transcription factor 11" P35716 2 5692384-5701385 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Transcription factors" "Differentiation, Neurogenesis, Transcription, Transcription regulation" "Activator, Developmental protein, DNA-binding" "Disease variant, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 5 "brain: 5.0" "Cell type enhanced" "Detected in some" "Breast glandular cells: 6.4;Breast myoepithelial cells: 8.6;Cardiomyocytes: 13.9;Inhibitory neurons: 8.4;Oligodendrocyte precursor cells: 21.6;Skeletal myocytes: 38.8" "Cancer enhanced" "Detected in many" "glioma: 8.5" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 47.2;NTERA-2: 23.6;REH: 17.9;RH-30: 18.2;SCLC-21H: 29.1;SH-SY5Y: 44.0" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA000448, HPA000536, CAB056152, CAB056153" Approved Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 42: Non-specific - Transcription" "Cluster 73: Brain - Neuropeptide signaling" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB056152: AB_2665567, CAB056153: AB_2665568, HPA000448: , HPA000536: AB_1080060" "unprognostic (2.17e-2)" "unprognostic (2.02e-2)" "unprognostic (1.44e-2)" "unprognostic (7.35e-6)" "unprognostic (2.79e-1)" "unprognostic (1.19e-1)" "unprognostic (4.04e-8)" "unprognostic (2.79e-2)" "unprognostic (7.27e-2)" "unprognostic (3.17e-1)" "unprognostic (3.35e-3)" "unprognostic (2.42e-1)" "unprognostic (8.45e-8)" "unprognostic (1.35e-1)" "unprognostic (1.96e-1)" "unprognostic (5.50e-3)" "unprognostic (7.47e-2)" 0.0 0.0 2.3 0.0 2.8 0.0 0.0 1.3 1.9 0.0 0.3 1.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 1.3 5.0 0.0 0.0 0.0 0.0 2.5 2.9 0.0 0.0 0.0 0.2 0.0 2.0 0.0 0.1 0.2 0.1 0.0 0.1 0.0 0.2 0.2 3.2 0.1 0.0 0.0 4.6 0.0 0.0 0.1 0.0 0.0 0.0 3.0 0.0 0.0 47.2 0.0 0.0 0.0 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.3 0.0 0.0 0.6 0.0 0.0 0.0 1.5 0.0 2.3 0.0 0.0 4.4 0.0 0.0 0.0 23.6 0.0 0.0 17.9 18.2 0.7 0.0 0.0 29.1 44.0 0.0 0.3 0.0 8.2 0.0 0.0 0.0 0.6 0.2 0.0 0.0 3.3 0.6 1.2 0.0 0.0 11.1 0.7 0.1 0.1 0.0 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.2 0.1 0.1 0.1 2.3 2.8 1.3 1.9 1.3 5.0 2.5 2.9 2.0 3.2 4.6 3.0 0.4 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 2.1 6.4 8.6 13.9 0.0 0.6 0.0 0.0 0.2 0.0 0.0 0.0 5.7 0.9 0.0 0.8 1.2 0.0 0.0 0.4 0.0 0.2 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 8.4 0.0 0.0 0.0 0.3 0.2 0.0 0.2 0.0 1.0 0.0 0.5 0.0 21.6 3.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.3 0.0 38.8 1.1 0.0 0.2 0.0 0.0 0.3 0.1 0.1 0.0 0.0 SPAG16 "DKFZp666P1710, FLJ22724, PF20, WDR29" ENSG00000144451 "Sperm associated antigen 16" Q8N0X2 2 213284379-214410501 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 243.1;Inhibitory neurons: 273.7;Respiratory ciliated cells: 330.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "T-47d: 70.3" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA037542 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane, Cytosol" "HPA037542: AB_10672353" "unprognostic (4.20e-2)" "unprognostic (2.73e-1)" "unprognostic (2.67e-1)" "unprognostic (9.79e-2)" "unprognostic (1.83e-1)" "unprognostic (1.30e-1)" "unprognostic (2.04e-2)" "unprognostic (1.76e-1)" "unprognostic (1.23e-1)" "unprognostic (1.15e-1)" "unprognostic (2.66e-1)" "prognostic unfavorable (4.90e-4)" "prognostic favorable (3.82e-4)" "unprognostic (1.10e-2)" "unprognostic (1.01e-1)" "unprognostic (3.41e-1)" "unprognostic (1.17e-1)" 16.3 16.8 36.6 6.4 37.4 2.4 20.8 35.1 45.9 21.0 39.0 16.5 18.8 18.2 31.6 26.1 46.5 22.0 22.2 34.2 37.8 30.4 18.8 10.8 11.5 38.8 39.6 25.8 15.5 24.4 29.7 9.8 37.8 22.1 17.2 21.5 15.7 20.5 10.3 24.9 10.9 12.1 40.9 8.0 26.1 46.3 38.4 13.0 26.4 10.8 13.8 18.9 19.4 40.6 26.8 9.9 29.4 0.0 19.3 35.0 0.2 14.3 17.1 18.3 19.3 20.8 28.8 11.1 16.7 16.0 29.3 18.5 13.4 17.4 38.6 0.0 10.5 5.8 28.0 24.6 21.9 6.3 0.1 30.1 23.5 16.3 9.5 25.0 7.6 11.6 18.8 12.3 18.4 0.0 21.4 0.1 16.3 0.0 8.7 22.6 30.9 0.5 29.4 25.8 21.4 25.1 16.3 15.1 21.3 24.2 70.3 2.7 7.8 17.2 9.2 9.3 15.1 20.0 9.7 0.4 28.6 0.0 8.0 2.0 0.3 0.9 8.1 1.3 11.7 9.3 9.1 10.4 3.1 8.5 12.0 10.4 0.5 15.4 0.9 5.1 9.4 3.4 36.6 37.4 35.1 45.9 34.2 37.8 38.8 39.6 37.8 40.9 38.4 40.6 17.7 16.0 19.5 89.5 10.7 42.3 46.6 82.8 22.8 47.6 38.0 45.6 67.5 74.4 73.6 40.5 95.9 50.6 7.5 17.1 76.3 44.0 243.1 207.0 31.3 18.5 38.2 9.0 205.9 24.9 20.8 30.8 32.1 30.3 10.1 34.0 12.8 16.9 11.7 40.4 273.7 37.8 101.7 4.6 9.6 86.2 41.3 5.9 23.2 42.2 29.2 82.7 8.2 92.0 74.9 27.3 18.8 44.8 9.4 25.4 9.4 94.9 330.0 69.0 13.1 30.8 36.1 167.9 31.0 64.6 56.4 23.5 12.9 55.3 39.8 53.8 SPART "KIAA0610, SPG20, TAHCCP1" ENSG00000133104 Spartin Q8N0X7 13 36301638-36370180 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant, Hereditary spastic paraplegia, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Granulosa cells: 75.0;Proximal tubular cells: 90.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in all" 5 "basophil: 172.7" "Lineage enriched" "Detected in all" 7 "granulocytes: 172.7" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039053, HPA039054" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 68: Epididymis - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 7: Non-specific - Mitochondria" Cytosol "Plasma membrane" "HPA039053: AB_10672769, HPA039054: AB_2676323" "unprognostic (3.73e-2)" "unprognostic (9.39e-2)" "unprognostic (3.06e-2)" "unprognostic (4.60e-2)" "unprognostic (2.21e-2)" "unprognostic (1.10e-2)" "unprognostic (9.18e-3)" "unprognostic (9.58e-2)" "unprognostic (3.36e-2)" "unprognostic (2.22e-1)" "unprognostic (7.62e-2)" "unprognostic (8.14e-2)" "unprognostic (1.54e-1)" "unprognostic (9.26e-2)" "unprognostic (1.22e-1)" "unprognostic (1.54e-2)" "unprognostic (5.79e-2)" 42.3 48.4 36.9 18.0 42.8 23.6 32.5 43.4 50.6 49.2 42.3 37.8 12.7 42.4 67.1 24.5 44.5 37.4 25.7 35.3 39.4 48.4 19.9 27.0 15.7 42.4 40.5 63.6 14.6 29.5 29.6 39.8 42.1 34.7 13.3 43.3 17.3 36.4 33.5 18.4 15.4 52.8 41.2 30.7 21.1 27.6 38.3 16.7 35.6 33.7 11.2 35.5 29.9 51.0 0.1 22.4 59.5 0.0 127.9 106.6 42.4 54.1 81.3 53.7 52.8 0.1 0.0 0.0 32.9 65.9 98.2 31.2 81.4 38.0 57.5 4.4 46.9 69.4 28.3 14.6 128.0 72.8 134.3 106.2 59.5 44.4 61.9 131.7 79.6 18.7 30.6 11.9 97.5 5.2 21.7 120.8 30.0 0.0 7.8 0.0 99.4 2.5 62.5 28.2 6.2 14.5 46.3 18.3 58.9 85.3 10.5 84.7 66.8 40.0 20.1 55.9 32.2 14.2 0.2 0.1 44.6 61.8 71.0 172.7 22.1 30.1 13.5 21.7 13.1 10.1 18.6 5.4 15.7 9.7 24.5 13.1 35.0 14.2 23.8 19.3 4.8 18.1 36.9 42.8 43.4 50.6 35.3 39.4 42.4 40.5 42.1 41.2 38.3 51.0 43.5 35.3 51.5 0.0 6.1 0.0 0.0 0.0 0.0 0.0 30.8 30.1 0.0 0.0 40.2 27.6 0.0 52.7 18.6 0.0 66.5 26.2 0.0 59.4 62.6 15.9 0.0 0.0 0.0 15.0 59.7 39.8 0.0 38.1 58.0 75.0 0.0 0.0 42.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 24.0 0.0 0.0 24.3 0.0 0.0 0.0 0.0 16.8 0.0 0.0 3.5 0.0 0.0 90.4 65.6 0.0 0.0 0.0 27.8 0.0 0.0 0.0 0.0 64.3 10.8 59.2 0.0 0.0 SPHK1 SPHK ENSG00000176170 "Sphingosine kinase 1" Q9NYA1 17 76376584-76387860 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Calmodulin-binding, Kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Ductal cells: 105.4;Muller glia cells: 165.1;Pancreatic endocrine cells: 101.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "plasmacytoid DC: 4.8" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "Hep G2: 127.6;TIME: 108.9;U-251 MG: 142.1" "Low region specificity" "Detected in many" "Region enhanced" "Detected in some" "olfactory bulb: 5.7" "HPA022829, HPA028761" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 1: Pancreatic cells - Digestion" "Plasma membrane, Cytosol" "HPA022829: AB_1857438, HPA028761: AB_10600814" "unprognostic (1.04e-1)" "unprognostic (6.30e-2)" "unprognostic (1.09e-2)" "unprognostic (8.66e-2)" "unprognostic (2.25e-2)" "unprognostic (1.82e-1)" "unprognostic (1.68e-2)" "unprognostic (9.32e-3)" "unprognostic (3.13e-1)" "unprognostic (7.43e-2)" "unprognostic (8.99e-3)" "unprognostic (2.18e-1)" "prognostic unfavorable (5.14e-6)" "unprognostic (1.39e-1)" "unprognostic (4.82e-2)" "unprognostic (8.29e-2)" "unprognostic (1.10e-3)" 18.9 4.1 4.0 10.5 3.0 17.3 18.0 2.1 3.9 11.0 2.3 7.0 1.9 6.7 3.9 23.8 9.4 11.9 17.5 2.9 3.9 21.4 3.8 24.3 8.1 4.0 4.1 4.3 14.4 4.8 4.9 2.5 4.5 7.3 1.1 8.4 19.9 1.5 3.2 15.6 7.0 3.2 2.3 5.0 6.7 5.8 8.5 3.5 10.6 0.8 4.1 11.3 13.1 3.9 36.9 3.7 15.2 0.8 7.6 7.0 15.8 82.6 54.0 67.8 40.8 19.4 3.9 1.8 7.4 61.0 28.9 7.7 11.7 105.4 16.4 1.6 6.2 0.5 28.3 127.6 16.6 1.3 2.9 13.6 2.1 105.9 41.3 28.8 66.0 3.7 17.3 0.2 13.5 46.6 3.5 0.6 0.9 8.2 29.7 2.5 4.1 2.8 3.7 0.5 2.0 3.6 8.3 0.9 74.4 9.1 3.0 5.1 108.9 105.8 20.8 82.3 142.1 1.7 0.4 1.6 80.5 6.5 16.1 1.5 1.9 0.0 0.7 0.9 0.2 0.0 0.1 0.2 0.5 0.1 0.0 0.1 0.2 0.0 0.2 4.8 0.0 0.8 4.0 3.0 2.1 3.9 2.9 3.9 4.0 4.1 4.5 2.3 8.5 3.9 22.0 0.0 0.0 1.0 2.8 12.6 57.0 18.6 2.8 1.5 31.1 29.1 5.3 47.1 6.6 1.8 0.0 1.2 9.1 1.0 0.0 105.4 0.2 15.3 13.5 51.2 0.0 22.3 0.5 12.7 16.9 27.5 3.1 60.7 7.0 0.4 4.2 0.2 30.1 33.7 1.6 2.4 6.1 8.9 45.4 1.4 3.7 39.9 12.4 1.0 61.5 165.1 3.1 0.0 0.1 101.8 1.2 19.9 3.5 68.9 0.8 2.5 2.0 3.9 0.0 17.3 54.3 0.0 9.5 6.7 10.7 1.4 4.2 0.8 0.4 27.0 SPINK13 "HESPINTOR, LiESP6, MGC149260, SPINK5L3" ENSG00000214510 "Serine peptidase inhibitor Kazal type 13" Q1W4C9 5 148268180-148286255 "Predicted intracellular proteins, Predicted secreted proteins" "Protease inhibitor, Serine protease inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 10 "epididymis: 328.8" "Group enriched" "Detected in some" 6 "Leydig cells: 39.7;Peritubular cells: 26.7" "Cancer enhanced" "Detected in some" "renal cancer: 3.9" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 19 "HeLa: 574.2" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA036456 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted in male reproductive system" NA NA "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 20: HeLa - Mitochondria" "Cluster 44: Endometrium - Transcription" "Plasma membrane" Nucleoplasm "HPA036456: AB_10673496" "unprognostic (5.22e-2)" "unprognostic (2.03e-1)" "unprognostic (1.44e-1)" "unprognostic (2.51e-1)" "unprognostic (1.22e-1)" "unprognostic (1.41e-2)" "unprognostic (6.43e-3)" "unprognostic (1.25e-3)" "unprognostic (5.01e-3)" "unprognostic (1.25e-1)" "prognostic unfavorable (4.03e-10)" "unprognostic (4.31e-2)" "unprognostic (1.72e-1)" "unprognostic (2.43e-1)" "unprognostic (2.95e-2)" 0.3 1.9 0.7 0.1 1.2 0.0 0.0 0.9 1.0 0.2 0.0 1.1 0.0 0.2 328.8 0.1 0.4 0.2 0.5 0.4 0.8 0.6 0.0 0.3 0.1 1.3 0.8 0.5 0.2 0.0 0.5 0.0 1.4 1.7 0.0 1.5 0.2 31.3 0.4 0.5 0.0 0.1 0.7 0.0 1.6 1.3 1.1 0.1 0.3 0.0 0.0 1.5 0.1 2.8 0.0 0.1 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.0 0.6 0.0 0.0 574.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.3 0.1 0.0 1.5 0.0 0.0 0.3 30.0 0.2 0.3 0.0 22.5 0.0 0.0 0.2 1.9 0.0 0.6 1.1 0.1 0.4 0.1 0.6 0.0 0.6 2.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 1.2 0.9 1.0 0.4 0.8 1.3 0.8 1.4 0.7 1.1 2.8 0.1 0.0 0.0 1.0 0.0 0.0 0.3 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 1.8 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.6 0.1 0.0 0.0 0.0 0.4 0.0 0.0 0.5 0.0 2.0 0.0 0.0 0.0 0.0 0.0 5.0 0.6 0.0 0.0 0.0 0.0 0.1 39.7 0.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 2.8 0.0 26.7 0.1 0.5 0.0 0.1 0.0 0.6 0.0 0.4 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 SPPL3 "DKFZP586C1324, IMP2, MGC126674, MGC126676, MGC90402, PSL4" ENSG00000157837 "Signal peptide peptidase like 3" Q8TCT6 12 120762510-120904358 "Enzymes, Predicted membrane proteins" "Hydrolase, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 192.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA004194, HPA059958" Uncertain Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 27: Brain & Skin - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 40: Granulosa cells - Unknown function" "Vesicles, Plasma membrane" "HPA004194: AB_2667171, HPA059958: AB_2684179" "unprognostic (3.29e-1)" "unprognostic (2.29e-2)" "unprognostic (3.39e-2)" "unprognostic (1.63e-1)" "unprognostic (2.06e-1)" "unprognostic (7.96e-3)" "prognostic unfavorable (1.29e-5)" "unprognostic (3.17e-2)" "unprognostic (1.10e-1)" "unprognostic (1.28e-1)" "unprognostic (2.48e-1)" "unprognostic (2.44e-1)" "unprognostic (2.66e-1)" "unprognostic (9.34e-2)" "unprognostic (9.92e-2)" "unprognostic (7.54e-2)" "unprognostic (9.40e-2)" 20.9 14.9 25.3 11.9 28.1 20.9 24.2 29.0 27.5 30.0 13.1 26.7 18.2 26.3 15.7 44.3 28.6 18.7 18.1 25.4 30.6 22.8 19.3 20.4 15.9 25.0 26.0 31.4 21.3 49.6 13.9 28.4 26.1 20.6 27.2 15.5 20.2 27.0 15.7 56.5 18.8 29.6 24.1 24.3 15.2 39.0 26.4 32.7 31.2 19.6 27.8 28.6 34.2 31.4 30.0 29.2 43.4 27.4 56.2 37.7 30.5 22.5 66.6 47.4 37.9 30.5 29.9 27.4 0.1 39.4 42.0 35.6 44.8 48.4 48.9 21.9 27.5 23.6 16.2 23.4 59.2 27.4 29.3 38.1 75.9 40.7 38.1 56.0 47.1 41.5 26.5 13.4 41.2 26.3 36.7 22.0 29.2 27.8 20.6 21.6 36.6 19.7 36.8 83.8 29.7 31.9 42.8 19.6 34.7 46.1 58.9 18.7 35.4 21.9 29.5 13.6 17.1 30.9 60.3 26.4 32.5 22.3 36.9 4.8 1.2 1.1 1.3 1.2 1.8 1.3 1.6 1.7 2.1 1.6 1.5 1.7 2.2 1.3 1.1 2.7 1.4 0.7 25.3 28.1 29.0 27.5 25.4 30.6 25.0 26.0 26.1 24.1 26.4 31.4 35.2 19.2 20.8 79.3 25.3 55.1 32.3 29.4 43.3 37.8 35.2 24.1 21.2 20.0 19.8 40.5 27.1 42.0 21.2 47.2 1.9 19.3 8.6 20.9 26.9 33.0 27.1 14.5 97.2 24.7 29.0 33.2 25.0 29.7 4.5 68.7 37.5 33.1 38.3 37.0 112.6 33.7 22.4 38.1 39.3 8.0 28.6 34.5 26.6 79.6 26.6 23.0 16.5 141.3 192.3 22.8 34.9 35.0 22.0 33.4 34.0 18.1 18.1 22.4 13.1 32.3 27.4 55.6 41.1 76.9 84.7 64.6 22.4 35.0 35.4 37.6 SPRED3 ENSG00000188766 "Sprouty related EVH1 domain containing 3" Q2MJR0 19 38388421-38399587 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 8.0;pituitary gland: 5.6" "Cell type enhanced" "Detected in many" "Bipolar cells: 6.6;Enteroendocrine cells: 10.8;Excitatory neurons: 9.8;Inhibitory neurons: 10.4" "Cancer enhanced" "Detected in many" "glioma: 3.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "hTERT-RPE1: 12.9;TIME: 15.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071521 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Nucleoplasm, Plasma membrane" "HPA071521: " "unprognostic (1.09e-1)" "unprognostic (1.88e-3)" "unprognostic (8.71e-3)" "unprognostic (3.35e-3)" "unprognostic (3.70e-2)" "unprognostic (2.00e-3)" "unprognostic (2.09e-3)" "unprognostic (7.77e-3)" "unprognostic (1.49e-1)" "unprognostic (9.22e-3)" "unprognostic (1.69e-2)" "unprognostic (3.09e-2)" "unprognostic (1.40e-11)" "unprognostic (6.21e-4)" "unprognostic (3.67e-1)" "unprognostic (1.04e-3)" "unprognostic (8.45e-3)" 0.7 0.4 3.2 1.0 3.7 0.3 0.5 0.5 5.0 0.6 0.4 0.5 1.8 0.4 0.3 0.4 0.6 0.7 0.7 4.5 8.0 2.3 0.2 0.7 0.2 4.4 5.0 0.3 1.1 1.7 5.6 0.3 4.6 1.0 0.2 1.5 0.5 0.3 0.9 0.8 1.3 0.8 1.1 0.1 0.4 1.1 5.0 0.1 0.6 0.0 0.2 0.6 0.5 2.7 0.3 1.2 4.0 3.3 0.6 1.9 2.3 8.1 5.3 2.6 2.4 0.4 0.8 0.2 2.9 2.7 2.1 0.1 0.7 1.0 2.4 0.8 1.5 0.1 0.3 0.5 1.4 2.2 0.1 1.3 0.9 6.2 1.8 12.9 8.3 0.6 0.7 1.5 8.1 0.4 0.0 0.1 1.8 0.5 4.0 1.0 1.4 0.1 5.7 0.7 0.2 3.1 0.2 0.2 0.4 1.7 0.7 0.1 15.9 2.9 9.0 2.4 4.5 0.6 0.3 0.6 9.8 0.3 5.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.0 0.1 0.0 0.0 3.2 3.7 0.5 5.0 4.5 8.0 4.4 5.0 4.6 1.1 5.0 2.7 1.1 0.0 0.0 2.0 0.4 0.0 1.3 0.4 1.2 6.6 1.5 2.4 1.2 0.0 0.3 1.8 2.1 0.5 0.3 0.5 0.0 1.0 2.0 0.7 1.1 1.5 10.8 0.0 9.8 0.6 0.3 0.5 0.0 1.6 0.0 0.3 0.7 0.0 0.1 1.7 10.4 1.2 0.0 0.0 0.0 0.2 0.3 0.5 0.0 1.0 0.0 1.9 1.0 5.0 2.2 3.0 0.1 0.0 0.0 1.2 2.7 0.1 0.1 0.3 0.0 2.3 1.2 1.5 1.0 0.5 0.1 0.8 0.4 0.2 0.8 0.7 SRD5A3 "FLJ13352, SRD5A2L, SRD5A2L1" ENSG00000128039 "Steroid 5 alpha-reductase 3" Q9H8P0 4 55346213-55373100 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted membrane proteins" Oxidoreductase "Cataract, Congenital disorder of glycosylation, Mental retardation" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal respiratory cells: 245.5;Club cells: 245.2;Pancreatic endocrine cells: 155.5;Respiratory ciliated cells: 195.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SK-BR-3: 79.6" "Low region specificity" "Detected in all" HPA027006 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 27: Brain & Skin - Unknown function" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Plasma membrane, Cytosol" "HPA027006: AB_1857469" "unprognostic (1.12e-2)" "unprognostic (1.01e-1)" "unprognostic (4.02e-2)" "prognostic favorable (9.39e-4)" "unprognostic (1.50e-2)" "unprognostic (4.81e-2)" "prognostic unfavorable (1.80e-6)" "unprognostic (9.31e-2)" "unprognostic (5.28e-2)" "unprognostic (1.81e-2)" "unprognostic (3.29e-3)" "unprognostic (1.18e-1)" "prognostic unfavorable (4.85e-10)" "unprognostic (4.16e-2)" "unprognostic (1.42e-1)" "unprognostic (1.43e-2)" "unprognostic (9.52e-2)" 12.5 12.0 10.4 2.5 11.5 3.7 12.2 11.0 12.4 12.9 9.2 7.3 3.8 6.8 4.2 26.1 5.6 10.3 9.3 10.7 10.1 9.6 14.5 10.5 2.5 11.0 11.2 3.1 20.2 7.0 5.9 4.0 10.8 7.4 4.1 1.5 16.4 2.9 6.3 15.4 7.0 2.6 10.9 6.8 9.7 3.3 10.9 6.0 7.6 5.4 6.0 10.0 14.7 12.7 9.7 4.3 10.3 10.1 29.4 20.4 5.6 10.4 9.3 2.4 5.4 6.5 19.5 21.2 11.7 11.0 11.1 7.0 5.3 7.9 3.9 6.6 17.1 12.3 5.2 15.8 9.2 23.7 6.1 17.6 14.5 5.4 5.3 7.8 14.4 38.5 21.2 47.7 21.1 10.8 36.0 10.3 13.0 53.2 9.3 11.4 3.3 14.0 12.8 7.9 16.0 9.1 10.7 79.6 8.3 9.0 9.4 17.9 8.3 25.0 4.7 2.0 8.1 28.6 15.8 7.9 34.1 29.5 25.9 25.6 35.8 11.7 16.1 56.5 18.6 12.5 12.0 15.2 30.2 12.7 10.2 14.4 1.8 8.6 59.5 61.7 12.5 23.1 10.4 11.5 11.0 12.4 10.7 10.1 11.0 11.2 10.8 10.9 10.9 12.7 25.4 9.6 15.9 4.6 7.8 13.6 13.3 245.5 5.2 4.9 43.8 29.3 5.3 34.3 245.2 5.5 4.2 27.0 21.2 12.2 3.9 93.4 3.2 51.2 31.0 19.6 12.0 14.9 11.1 105.4 106.0 16.2 13.3 105.9 14.0 6.7 17.5 18.6 63.4 10.1 17.1 22.6 57.0 32.4 34.1 0.5 1.8 27.6 24.9 4.7 31.3 21.9 18.6 8.5 23.4 155.5 10.0 5.7 16.8 17.5 9.4 18.4 195.0 3.9 13.1 13.3 28.2 3.5 20.1 32.7 29.7 7.5 7.2 15.4 23.3 108.6 ST8SIA5 SIAT8E ENSG00000101638 "ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5" O15466 18 46667821-46759257 "Metabolic proteins, Predicted membrane proteins" "Glycosyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "adrenal gland: 12.2;brain: 17.0;parathyroid gland: 6.2" "Group enriched" "Detected in some" 5 "Excitatory neurons: 106.1;Inhibitory neurons: 75.5;Oligodendrocyte precursor cells: 32.2" "Cancer enriched" "Detected in single" 8 "glioma: 2.6" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 10 "WM-115: 87.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA043813, HPA046771" Approved Approved "Plasma membrane,Midbody" Yes NA 24000 "Cluster 6: Brain - Smell perception" "Cluster 17: WM-115 - Nervous system development" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Midbody" "HPA043813: AB_2678683, HPA046771: AB_2679798" "unprognostic (3.19e-2)" "unprognostic (1.16e-1)" "unprognostic (2.47e-2)" "unprognostic (1.33e-4)" "unprognostic (2.99e-2)" "unprognostic (4.83e-2)" "unprognostic (1.90e-2)" "unprognostic (1.39e-2)" "unprognostic (1.35e-1)" "unprognostic (1.36e-1)" "unprognostic (1.57e-2)" "unprognostic (1.84e-2)" "unprognostic (6.55e-2)" "unprognostic (8.85e-2)" "unprognostic (1.18e-1)" "unprognostic (1.12e-1)" "unprognostic (1.79e-2)" 0.1 12.2 4.0 0.0 12.9 0.2 0.0 17.0 11.4 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 3.1 6.2 0.0 1.0 0.0 0.0 0.0 0.4 0.1 0.1 0.0 6.2 0.5 0.0 1.4 0.1 0.0 0.7 0.0 0.0 2.7 0.1 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.6 0.0 0.0 0.0 7.7 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 5.1 4.2 0.2 0.0 0.1 9.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 8.3 0.0 87.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 4.0 12.9 17.0 11.4 6.2 0.0 0.4 0.1 1.4 0.0 0.0 7.7 0.1 0.0 0.0 5.2 0.0 0.0 0.0 0.0 0.0 3.4 0.1 0.0 7.8 0.0 0.0 1.8 0.0 0.0 0.0 0.1 1.9 0.0 3.1 0.0 0.1 0.2 0.0 0.0 106.1 0.0 0.0 0.2 0.0 0.0 0.0 12.9 0.0 0.0 0.1 0.0 75.5 0.2 0.0 0.0 0.0 7.3 0.0 0.0 0.0 3.7 0.0 1.1 0.0 32.2 9.1 0.1 0.0 0.4 0.0 0.2 0.0 0.1 0.2 0.6 0.0 0.6 0.2 0.8 0.1 0.0 0.0 0.0 0.0 7.7 0.0 0.1 STAC STAC1 ENSG00000144681 "SH3 and cysteine rich domain" Q99469 3 36380503-36548007 "Predicted intracellular proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "prostate: 13.8" "Cell type enhanced" "Detected in some" "Distal tubular cells: 5.9;Early spermatids: 5.2;granulocytes: 6.3;Granulosa cells: 12.5;Late spermatids: 5.3;Muller glia cells: 21.6;Smooth muscle cells: 5.0" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Group enriched" "Detected in some" 5 "eosinophil: 1.5;NK-cell: 1.3;T-reg: 1.5" "Group enriched" "Detected in many" 5 "granulocytes: 1.5;NK-cells: 1.3;T-cells: 1.5" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 46.8;HaCaT: 34.1;SH-SY5Y: 49.1;U-251 MG: 30.3;U-87 MG: 48.1" "Low region specificity" "Detected in many" HPA035143 Uncertain Uncertain "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 89: Fibroblasts - ECM organization" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 40: Granulosa cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA035143: AB_10603892" "unprognostic (5.29e-2)" "unprognostic (7.61e-2)" "unprognostic (2.58e-1)" "unprognostic (1.44e-6)" "unprognostic (4.24e-2)" "unprognostic (1.83e-2)" "unprognostic (3.06e-2)" "unprognostic (3.89e-1)" "unprognostic (2.02e-1)" "unprognostic (3.31e-3)" "unprognostic (1.77e-3)" "unprognostic (5.82e-2)" "unprognostic (8.07e-2)" "unprognostic (1.73e-4)" "unprognostic (8.93e-2)" "unprognostic (1.95e-1)" "unprognostic (7.94e-3)" 2.8 5.1 1.4 0.6 1.9 0.4 1.9 3.6 3.9 7.0 5.0 3.6 0.1 1.4 0.3 2.1 3.2 2.7 0.7 0.8 4.3 2.5 0.9 11.1 0.4 2.3 2.5 2.5 0.1 10.1 1.1 0.3 6.9 13.8 0.7 5.8 1.3 4.4 1.6 1.2 0.4 3.4 1.9 0.6 0.9 1.9 2.1 0.7 0.5 5.3 0.2 3.7 2.2 0.5 7.7 3.3 1.6 0.0 6.5 2.1 0.1 19.9 0.4 4.0 4.6 0.0 0.0 0.0 7.8 46.8 13.0 34.1 2.4 8.2 4.1 0.0 7.2 1.1 10.0 0.2 0.0 20.3 0.4 2.4 0.2 0.1 0.7 27.6 0.0 1.8 0.0 0.4 0.5 0.0 4.1 0.2 13.8 0.0 3.0 0.0 0.0 0.0 10.8 0.0 6.2 49.1 7.9 5.2 0.1 13.6 0.0 2.0 8.5 0.5 19.1 0.6 30.3 0.0 0.0 0.0 48.1 7.9 8.3 0.0 0.0 1.5 0.0 0.2 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1.5 0.0 1.4 1.9 3.6 3.9 0.8 4.3 2.3 2.5 6.9 1.9 2.1 0.5 0.9 0.0 0.5 0.3 0.0 0.0 0.0 0.5 0.0 0.7 2.3 0.8 0.9 0.0 1.3 0.0 0.0 0.0 0.1 0.0 5.9 0.2 5.2 0.9 0.5 0.4 0.0 2.1 0.6 0.0 0.1 1.5 0.0 2.1 6.3 12.5 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 2.2 5.3 0.0 4.8 0.0 0.0 0.0 21.6 0.0 0.5 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.6 0.0 0.4 5.0 1.8 0.1 0.0 0.3 0.0 0.4 0.0 0.0 0.0 STAT2 STAT113 ENSG00000170581 "Signal transducer and activator of transcription 2" P52630 12 56341597-56360167 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Antiviral defense, Host-virus interaction, Transcription, Transcription regulation" "Activator, DNA-binding" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 111.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB003858, HPA018888" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 64: Macrophages - Immune response" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 59: Non-specific - Transcription" Cytosol "Plasma membrane" "CAB003858: AB_562227, HPA018888: AB_1857550" "unprognostic (3.03e-1)" "unprognostic (8.59e-2)" "unprognostic (6.92e-3)" "prognostic unfavorable (4.75e-4)" "unprognostic (1.10e-1)" "unprognostic (1.52e-1)" "unprognostic (7.27e-2)" "unprognostic (1.93e-1)" "unprognostic (2.60e-1)" "unprognostic (4.12e-3)" "unprognostic (1.56e-1)" "unprognostic (7.45e-3)" "prognostic unfavorable (4.78e-13)" "unprognostic (1.88e-1)" "unprognostic (5.56e-2)" "unprognostic (2.77e-1)" "unprognostic (1.46e-3)" 17.3 6.3 2.6 19.2 2.3 7.8 10.3 2.7 3.1 18.7 2.9 10.7 10.7 11.3 5.6 11.1 12.9 20.1 8.1 3.1 2.3 8.4 20.6 22.8 19.6 4.2 2.0 17.4 9.9 12.4 8.6 15.9 3.1 10.3 12.5 5.6 18.1 9.9 4.0 7.8 13.0 21.8 5.9 25.2 10.3 4.0 4.6 19.9 10.7 8.4 20.1 18.4 5.6 6.2 15.5 8.5 11.8 12.5 98.3 58.6 26.1 19.4 94.0 92.4 93.1 8.7 16.4 17.9 22.6 38.6 24.2 14.9 21.0 15.1 18.0 13.8 4.7 27.2 7.6 9.3 58.8 5.0 20.2 86.8 13.4 19.5 22.8 70.5 25.6 14.3 15.2 44.7 35.1 9.4 7.3 3.5 5.2 15.1 9.8 6.9 22.1 17.1 21.3 18.1 4.2 10.1 31.5 18.8 43.1 22.7 16.4 17.7 11.2 22.2 10.7 8.0 3.1 32.5 32.9 9.8 30.3 7.2 9.9 14.8 17.2 11.3 7.7 22.8 7.9 5.2 7.4 7.7 11.6 7.5 5.2 5.1 6.8 4.8 18.3 10.2 9.8 13.1 2.6 2.3 2.7 3.1 3.1 2.3 4.2 2.0 3.1 5.9 4.6 6.2 36.0 12.8 41.7 40.5 24.0 14.3 10.3 13.7 17.1 17.0 17.4 15.0 11.1 15.7 24.4 18.4 20.9 11.2 28.1 23.8 1.9 14.0 13.8 20.7 36.4 26.5 15.5 8.6 29.8 10.7 24.5 27.6 19.9 26.6 10.1 24.6 27.8 64.8 25.9 3.3 28.6 16.8 6.1 50.9 25.6 43.7 19.6 45.2 32.0 24.4 42.3 10.4 18.6 27.6 111.8 11.9 21.9 17.3 24.4 11.4 24.0 10.7 24.2 21.8 26.3 20.3 22.5 3.2 5.0 12.5 14.5 11.1 20.1 13.7 14.8 13.2 STEAP4 "FLJ23153, SchLAH, STAMP2, TIARP, TNFAIP9" ENSG00000127954 "STEAP4 metalloreductase" Q687X5 7 88270892-88306894 "Enzymes, Predicted membrane proteins, Transporters" "Electron transport, Ion transport, Iron transport, Transport" Oxidoreductase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "adipose tissue: 113.7" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 402.5;Club cells: 152.8;Sertoli cells: 460.2;Smooth muscle cells: 255.3" "Cancer enhanced" "Detected in many" "prostate cancer: 45.9" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in some" 12 "neutrophil: 163.6" "Lineage enriched" "Detected in many" 12 "granulocytes: 163.6" "Group enriched" "Detected in some" 6 "HSkMC: 122.1;SiHa: 119.7;U-2197: 166.4" "Not detected" "Not detected" "Not detected" "Not detected" HPA065201 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 50: Neutrophils - Cellular senescence" "Cluster 82: Adipose tissue - ECM organization" "Cluster 18: U-2197 - ECM organization" "Cluster 48: Smooth muscle cells - ECM organization" "Nucleoplasm, Plasma membrane" "HPA065201: " "unprognostic (3.76e-2)" "unprognostic (2.16e-2)" "unprognostic (8.82e-2)" "unprognostic (1.43e-1)" "unprognostic (1.62e-1)" "unprognostic (9.96e-2)" "prognostic favorable (2.97e-4)" "unprognostic (7.40e-2)" "unprognostic (3.12e-1)" "unprognostic (4.66e-2)" "unprognostic (4.21e-1)" "unprognostic (2.98e-1)" "unprognostic (7.51e-3)" "prognostic unfavorable (5.77e-4)" "unprognostic (1.72e-1)" "unprognostic (2.00e-1)" "unprognostic (4.53e-2)" 113.7 46.3 1.0 31.7 0.9 7.1 68.6 2.8 1.5 21.3 17.0 13.3 3.8 17.9 7.8 15.4 36.1 22.7 24.1 1.4 1.0 11.8 24.3 67.5 7.2 1.2 0.9 4.4 10.6 16.0 13.0 15.3 0.8 60.0 9.2 1.9 26.8 10.6 13.4 19.3 10.6 29.3 0.4 5.4 10.6 13.4 1.1 7.8 53.1 16.6 5.1 34.3 22.7 1.1 4.9 0.0 0.1 0.1 0.1 1.9 0.3 0.0 0.3 0.0 0.1 0.1 23.6 0.1 0.1 0.0 0.4 18.7 0.1 0.0 0.1 0.0 0.1 0.1 7.9 0.1 0.1 0.1 0.2 122.1 0.1 0.4 0.9 0.0 0.0 0.1 0.3 0.4 0.0 3.0 0.1 0.5 0.1 1.0 0.0 0.2 0.1 0.3 0.0 0.3 0.2 0.2 119.7 9.9 0.0 0.1 0.8 0.0 0.1 0.4 0.3 166.4 0.1 0.1 0.1 0.1 0.2 0.9 0.2 0.4 13.5 1.4 0.0 0.8 0.0 0.0 0.0 0.0 1.0 0.1 0.0 0.0 163.6 0.2 0.1 0.3 0.0 3.2 1.0 0.9 2.8 1.5 1.4 1.0 1.2 0.9 0.8 0.4 1.1 1.1 77.2 54.5 402.5 0.0 0.8 9.4 5.8 8.6 1.8 1.8 21.6 8.3 9.1 0.0 152.8 0.0 2.1 0.4 1.1 0.4 0.0 14.6 23.8 14.6 20.5 14.7 0.0 0.0 0.5 9.6 10.6 39.8 1.1 51.2 16.4 0.0 15.4 0.7 2.8 0.0 0.8 0.2 16.2 7.2 7.4 10.9 114.9 12.2 5.4 6.5 19.0 2.7 0.0 1.0 0.1 18.6 0.0 9.1 0.2 49.3 0.1 0.1 72.8 0.3 460.2 9.6 255.3 0.9 0.3 1.5 18.8 10.9 3.1 57.7 0.2 16.6 STIL "MCPH7, SIL" ENSG00000123473 "STIL centriolar assembly protein" Q15468 1 47250139-47314147 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Developmental protein" "Cancer-related genes, Disease variant, Mental retardation, Primary microcephaly, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 10.8;lymphoid tissue: 9.9" "Cell type enhanced" "Detected in many" "Erythroid cells: 12.8;Glandular and luminal cells: 12.4;Spermatocytes: 17.8;Spermatogonia: 14.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in many" HPA046543 Approved "Plasma membrane,Cytosol" NA Yes "Cluster 40: NK-cells - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA046543: AB_2679692" "unprognostic (2.07e-1)" "unprognostic (6.29e-2)" "unprognostic (5.54e-3)" "unprognostic (2.67e-3)" "unprognostic (1.76e-1)" "unprognostic (1.56e-2)" "unprognostic (2.90e-5)" "unprognostic (7.35e-3)" "unprognostic (4.04e-3)" "unprognostic (1.41e-1)" "prognostic unfavorable (1.33e-4)" "unprognostic (5.81e-2)" "unprognostic (3.36e-14)" "unprognostic (5.76e-3)" "unprognostic (2.58e-1)" "unprognostic (1.64e-1)" "unprognostic (2.28e-1)" 1.0 0.5 0.8 3.0 0.8 10.8 2.9 0.7 1.2 1.1 0.2 4.1 2.9 1.4 1.4 2.5 0.9 1.4 0.6 0.8 0.6 0.7 1.0 0.9 4.9 0.7 0.6 0.8 0.7 0.9 0.4 1.9 0.8 1.3 5.6 1.2 1.7 0.5 0.6 3.1 2.7 1.4 0.4 1.4 1.8 6.6 0.8 9.9 0.9 0.7 5.7 1.1 1.0 1.0 33.7 17.4 24.7 22.1 1.8 3.8 15.7 29.3 14.0 32.0 33.2 18.5 16.1 39.4 13.3 14.4 32.7 21.4 29.4 15.3 33.7 29.6 12.9 44.5 20.9 16.6 0.8 35.7 21.5 1.6 2.1 27.2 17.5 3.8 21.5 29.5 31.7 35.9 24.1 14.3 35.6 10.9 30.0 18.6 14.2 23.0 40.3 19.0 9.0 20.0 22.0 13.2 31.4 22.2 14.6 29.6 14.5 20.6 12.2 29.6 29.9 21.2 40.0 11.9 26.4 38.1 13.8 27.0 28.0 0.3 0.1 0.2 0.2 0.0 0.0 0.4 0.2 0.2 0.1 0.2 0.0 0.1 0.3 0.7 0.0 0.3 0.3 0.1 0.8 0.8 0.7 1.2 0.8 0.6 0.7 0.6 0.8 0.4 0.8 1.0 1.6 3.2 0.5 2.0 2.4 0.9 0.6 2.0 1.2 1.1 2.8 3.0 0.5 0.0 2.3 0.0 4.2 2.5 1.6 5.4 0.0 1.6 1.6 7.8 3.2 2.2 1.8 12.8 5.1 0.4 4.4 1.6 3.1 12.4 2.5 8.2 1.4 0.5 2.9 0.0 3.9 6.1 0.0 2.4 1.2 1.1 0.3 2.7 0.0 0.0 3.0 0.8 1.0 2.0 4.8 1.9 1.8 0.7 10.2 1.1 1.4 0.4 7.6 0.6 0.0 1.7 2.0 17.8 14.4 5.3 2.4 0.8 3.3 2.6 5.5 1.4 STK10 "LOK, PRO2729" ENSG00000072786 "Serine/threonine kinase 10" O94804 5 172042079-172188224 "Disease related genes, Enzymes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" "Cell cycle" "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 76.5;lymphoid tissue: 45.2" "Cell type enhanced" "Detected in all" "dendritic cells: 107.7;Kupffer cells: 91.4;NK-cells: 171.0;T-cells: 81.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "WM-115: 143.3" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA015083, CAB020840" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 16000 "Cluster 51: Monocytes - Innate immune response" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 17: WM-115 - Nervous system development" "Cluster 63: NK-cells & T-cells - Immune response" "Nucleoplasm, Plasma membrane" "CAB020840: , HPA015083: AB_2669151" "unprognostic (1.17e-1)" "unprognostic (5.43e-2)" "prognostic favorable (2.76e-4)" "unprognostic (2.88e-1)" "unprognostic (6.96e-3)" "unprognostic (1.02e-1)" "unprognostic (5.25e-3)" "unprognostic (3.07e-2)" "unprognostic (1.07e-1)" "unprognostic (1.03e-1)" "unprognostic (2.65e-1)" "unprognostic (3.43e-1)" "prognostic unfavorable (1.63e-4)" "unprognostic (1.09e-1)" "unprognostic (1.01e-2)" "unprognostic (3.10e-1)" "unprognostic (1.84e-1)" 14.9 5.7 3.1 37.1 3.6 76.5 11.4 18.4 5.6 4.5 3.5 8.5 8.4 4.9 1.7 5.6 4.7 13.2 7.6 3.1 4.0 5.9 6.2 18.4 44.1 6.2 4.4 2.5 7.2 3.1 4.1 17.2 5.8 4.4 6.9 1.2 4.7 3.5 5.0 14.2 16.0 7.8 5.4 45.2 11.1 14.0 6.4 20.6 5.3 5.5 25.0 14.9 5.2 7.0 22.2 20.2 12.7 18.8 14.7 18.1 31.5 28.4 24.0 20.2 18.9 10.6 28.6 26.8 14.6 35.6 42.3 25.4 5.7 35.1 13.5 35.0 9.3 32.1 8.2 6.1 20.2 32.7 36.4 17.4 7.5 27.4 23.1 7.5 18.3 10.4 3.0 36.2 14.7 35.7 23.5 73.4 5.0 11.3 16.1 38.2 9.9 17.7 8.2 27.6 8.3 10.2 16.4 22.5 77.9 15.6 8.2 68.7 24.8 22.3 11.3 15.8 15.5 30.2 48.4 17.1 29.4 49.8 143.3 16.7 26.5 23.4 36.5 46.3 26.9 10.0 19.3 26.3 22.5 8.1 11.0 20.0 48.9 16.9 71.8 7.1 26.7 44.0 3.1 3.6 18.4 5.6 3.1 4.0 6.2 4.4 5.8 5.4 6.4 7.0 35.8 3.2 11.2 1.6 40.5 6.6 8.4 7.2 5.7 4.3 3.3 3.7 3.8 5.7 6.1 1.8 6.2 4.1 107.7 11.8 1.9 4.5 2.5 3.5 4.6 23.9 12.0 11.8 8.5 6.2 27.2 9.3 20.9 7.1 28.4 3.6 18.2 2.3 36.3 47.1 7.9 19.9 2.0 91.4 43.8 3.2 2.8 61.3 8.8 32.8 49.8 2.1 171.0 10.1 14.4 10.7 11.8 1.5 42.8 11.7 6.5 2.0 6.1 2.2 13.1 5.1 10.2 5.3 7.8 2.6 4.1 5.1 81.4 11.4 5.3 10.7 STK17A DRAK1 ENSG00000164543 "Serine/threonine kinase 17a" Q9UEE5 7 43582758-43650713 "Enzymes, Metabolic proteins, Plasma proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 644.6;T-cells: 273.7;Urothelial cells: 326.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA018138, HPA037979" Uncertain Supported "Nuclear speckles,Plasma membrane" Yes No "Cluster 48: NK-cells - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 22: Epithelial cell types - Mixed function" "Nuclear speckles" "Plasma membrane" "HPA018138: AB_2669784, HPA037979: AB_10795247" "unprognostic (1.81e-3)" "unprognostic (1.08e-2)" "unprognostic (2.67e-1)" "unprognostic (5.41e-2)" "unprognostic (5.11e-2)" "unprognostic (3.35e-2)" "unprognostic (1.03e-2)" "unprognostic (9.15e-3)" "unprognostic (2.07e-1)" "unprognostic (6.34e-2)" "unprognostic (1.36e-2)" "unprognostic (6.61e-2)" "unprognostic (2.99e-3)" "unprognostic (3.76e-2)" "unprognostic (3.08e-1)" "unprognostic (1.97e-3)" "unprognostic (3.66e-1)" 6.7 8.1 3.9 7.9 4.2 4.8 5.2 6.9 4.9 4.0 4.0 6.4 3.2 3.5 1.2 7.2 3.9 5.3 10.8 4.0 4.1 6.3 4.6 9.4 14.4 3.4 4.4 6.2 9.1 0.8 4.2 3.2 3.6 4.3 2.4 5.5 5.8 2.1 9.9 4.6 11.5 3.3 3.6 12.6 9.5 9.0 4.3 9.0 3.8 2.5 13.5 5.6 5.0 3.1 5.8 8.2 9.0 5.3 7.8 8.3 1.9 12.3 15.1 6.6 5.9 7.5 3.1 7.9 20.2 15.3 17.8 8.5 3.6 17.4 10.4 16.9 7.0 9.3 8.2 8.4 4.9 21.1 5.6 6.4 26.4 8.2 8.6 36.4 12.6 11.0 16.7 15.1 9.6 3.6 18.2 8.0 17.3 4.1 18.3 8.4 6.9 14.2 15.6 6.7 6.9 11.2 8.1 8.5 6.1 13.6 6.5 10.8 16.9 20.7 8.3 14.3 17.2 13.3 11.2 13.5 18.4 14.0 31.7 0.5 0.0 2.7 2.0 0.0 1.5 2.4 2.0 3.2 0.1 2.2 3.0 3.0 1.6 4.9 0.1 0.4 1.3 0.9 3.9 4.2 6.9 4.9 4.0 4.1 3.4 4.4 3.6 3.6 4.3 3.1 44.2 121.8 33.1 29.0 237.8 181.9 644.6 64.5 99.6 2.9 17.7 37.8 28.7 7.2 69.8 20.2 10.4 54.8 222.3 54.4 33.2 153.0 47.0 129.1 17.4 35.2 7.2 54.1 9.5 95.4 23.3 39.1 78.0 88.3 38.8 17.7 17.9 9.6 16.9 0.0 5.6 34.3 38.7 20.3 65.9 14.7 5.9 60.9 35.6 34.7 42.1 7.9 221.4 39.2 3.7 89.4 73.0 2.6 81.2 192.6 23.8 13.2 42.4 26.3 6.6 39.4 51.3 75.8 36.1 42.3 136.1 66.8 273.7 27.0 18.0 326.1 STK17B DRAK2 ENSG00000081320 "Serine/threonine kinase 17b" O94768 2 196133583-196176503 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" Apoptosis "Kinase, Serine/threonine-protein kinase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "bone marrow: 376.2;lymphoid tissue: 113.3" "Cell type enhanced" "Detected in many" "B-cells: 229.3;dendritic cells: 267.7;granulocytes: 195.1;Langerhans cells: 201.3;Macrophages: 198.9;Plasma cells: 191.8;T-cells: 342.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "Daudi: 122.3;HMC-1: 118.9;Karpas-707: 111.6;U-698: 132.1" "Region enriched" "Detected in all" 5 "cerebellum: 63.4" "Low region specificity" "Detected in all" HPA034858 Enhanced Uncertain "Plasma membrane,Cytosol" NA Yes "Cluster 5: Granulocytes - Unknown function" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane, Cytosol" "HPA034858: AB_10670981" "unprognostic (2.14e-1)" "unprognostic (2.45e-3)" "unprognostic (3.68e-2)" "unprognostic (3.61e-2)" "unprognostic (3.63e-2)" "unprognostic (7.43e-3)" "unprognostic (1.75e-1)" "unprognostic (7.63e-2)" "unprognostic (9.15e-2)" "unprognostic (1.14e-1)" "unprognostic (9.90e-2)" "unprognostic (1.52e-1)" "prognostic unfavorable (5.72e-8)" "unprognostic (1.88e-1)" "unprognostic (1.19e-2)" "unprognostic (2.64e-2)" "unprognostic (5.80e-2)" 28.2 8.9 2.1 67.0 2.9 376.2 21.5 3.7 5.3 24.2 3.3 19.1 27.8 5.4 1.8 11.9 5.8 20.4 4.6 4.1 3.3 6.5 8.5 23.6 113.3 3.1 2.0 2.2 12.7 2.1 3.0 16.7 3.2 10.5 17.5 0.4 17.0 5.7 2.4 11.2 40.1 16.8 2.2 56.9 20.1 9.5 4.0 60.9 7.2 3.5 111.1 24.4 5.2 2.9 11.0 7.5 11.2 4.2 47.7 18.1 12.4 25.7 38.4 27.7 28.5 22.8 3.9 122.3 23.1 14.8 7.3 7.4 4.7 11.1 33.4 21.8 12.7 11.6 9.1 2.2 14.2 47.0 118.9 23.1 10.9 34.3 17.7 39.2 11.5 28.5 9.1 111.6 69.4 5.9 61.6 106.0 6.3 19.9 17.2 10.1 67.5 37.4 16.3 25.6 4.2 4.2 6.6 6.4 5.4 17.2 4.3 24.3 14.0 26.8 13.1 19.3 14.7 45.5 78.9 132.1 20.2 15.9 12.1 165.1 74.3 163.1 43.7 81.3 55.4 49.2 77.0 52.8 53.0 58.6 98.6 82.4 236.7 40.8 113.1 37.7 73.8 89.3 2.1 2.9 3.7 5.3 4.1 3.3 3.1 2.0 3.2 2.2 4.0 2.9 23.3 89.8 74.0 48.3 229.3 59.9 27.1 15.1 10.8 0.9 28.9 15.2 2.6 12.8 42.5 11.0 0.0 7.9 267.7 54.0 3.9 6.6 6.8 15.3 14.1 11.3 3.0 68.8 3.4 2.8 24.0 27.2 38.2 26.5 195.1 47.4 5.3 2.4 26.1 0.0 3.1 13.9 18.3 151.1 201.3 3.6 5.6 198.9 58.7 11.2 158.0 0.6 118.4 17.6 0.7 10.9 41.6 4.5 191.8 34.3 80.7 2.5 26.9 0.3 6.6 49.7 19.7 41.1 26.3 16.4 63.4 5.1 342.5 22.6 13.2 53.8 STOML2 "HSPC108, SLP-2" ENSG00000165283 "Stomatin like 2" Q9UJZ1 9 35099776-35103195 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015944, HPA062016" Supported Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 44000 "Cluster 12: Non-specific - Basic cellular processes" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "CAB015944: , HPA062016: AB_2684659" "unprognostic (2.49e-1)" "unprognostic (2.69e-1)" "unprognostic (1.20e-2)" "unprognostic (9.43e-2)" "unprognostic (1.29e-1)" "unprognostic (6.13e-2)" "prognostic unfavorable (4.77e-4)" "unprognostic (5.14e-2)" "unprognostic (4.25e-2)" "unprognostic (1.04e-2)" "unprognostic (9.06e-2)" "unprognostic (1.45e-1)" "prognostic favorable (3.00e-5)" "unprognostic (2.74e-2)" "unprognostic (5.26e-1)" "unprognostic (2.67e-1)" "unprognostic (5.47e-2)" 63.6 93.3 45.4 39.1 46.2 66.7 62.0 47.5 49.0 58.4 61.3 75.3 55.6 64.2 49.4 84.7 57.3 33.2 123.4 46.2 46.6 75.4 99.2 43.7 46.6 44.7 45.9 59.4 69.5 71.9 42.3 46.2 45.3 49.0 67.2 23.5 59.3 48.4 171.2 71.0 61.2 54.0 45.9 53.1 75.8 42.8 48.2 55.1 48.6 111.7 59.5 64.5 56.5 45.4 219.6 248.1 130.3 195.7 93.3 111.1 139.5 105.9 153.5 292.6 212.5 283.2 99.6 183.2 72.9 135.2 210.6 91.4 201.3 235.8 193.7 158.1 185.0 112.7 202.6 269.7 272.1 215.8 124.0 141.9 181.1 238.6 283.2 92.2 193.8 183.6 186.5 109.1 144.8 176.0 193.5 377.6 205.3 162.4 155.2 166.6 110.3 197.0 159.5 128.9 120.4 146.3 60.0 158.0 141.7 92.5 109.7 139.1 106.2 99.7 141.1 84.4 190.4 76.1 140.3 173.8 132.7 134.3 137.1 67.8 73.0 42.5 64.7 65.8 77.8 91.4 73.1 74.1 98.0 87.0 69.2 63.8 12.9 98.1 49.3 121.8 115.5 114.4 45.4 46.2 47.5 49.0 46.2 46.6 44.7 45.9 45.3 45.9 48.2 45.4 63.9 41.7 33.1 6.5 66.8 96.4 123.8 172.9 83.6 36.6 104.5 118.7 83.4 108.7 92.5 49.7 8.4 233.6 48.3 116.1 250.5 144.3 77.2 72.7 76.3 66.4 98.8 106.2 7.8 153.4 245.2 74.9 66.3 47.3 84.3 111.3 61.4 111.3 132.7 18.5 8.1 145.9 73.2 41.0 68.3 22.9 75.2 47.9 99.6 5.6 84.5 83.9 56.7 2.5 8.8 137.2 117.5 69.6 126.1 177.6 197.7 290.1 85.8 37.1 52.6 66.5 95.6 73.1 110.0 119.2 114.5 166.4 51.2 153.2 222.2 148.7 STX18 Ufe1 ENSG00000168818 "Syntaxin 18" Q9P2W9 4 4415742-4542346 "Predicted intracellular proteins, Predicted membrane proteins" "ER-Golgi transport, Protein transport, Transport" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 119.9" "Cell type enhanced" "Detected in all" "Endometrial ciliated cells: 191.1;Glandular and luminal cells: 249.4" "Cancer enriched" "Detected in all" 5 "endometrial cancer: 43.1" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003019 Approved Supported "Endoplasmic reticulum,Plasma membrane" NA NA "Cluster 47: Plasmacytoid DCs - Protein folding" "Cluster 89: Fibroblasts - ECM organization" "Cluster 38: EFO-21 - Unknown function" "Cluster 44: Endometrium - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA003019: AB_1857622" "unprognostic (2.33e-1)" "unprognostic (1.65e-1)" "prognostic favorable (2.84e-4)" "prognostic favorable (6.33e-8)" "unprognostic (4.21e-1)" "unprognostic (6.77e-2)" "unprognostic (6.17e-3)" "unprognostic (2.95e-2)" "unprognostic (7.53e-2)" "unprognostic (3.22e-3)" "unprognostic (1.21e-1)" "unprognostic (1.07e-2)" "prognostic favorable (7.03e-4)" "unprognostic (1.92e-2)" "unprognostic (1.55e-1)" "unprognostic (7.44e-2)" "prognostic favorable (4.69e-4)" 10.6 16.0 8.4 10.9 9.4 12.0 10.9 8.9 10.4 119.9 14.5 12.8 18.1 53.9 8.2 10.7 48.6 14.0 13.0 7.9 9.9 29.2 15.7 10.8 13.2 9.4 8.9 11.3 22.5 16.9 14.6 12.8 10.1 10.6 13.4 8.3 12.1 8.9 16.5 12.0 15.6 15.7 8.2 10.6 18.5 30.5 10.2 9.4 11.3 9.9 12.4 11.0 11.8 9.3 26.6 16.7 19.3 20.0 16.2 23.7 26.1 30.1 26.9 27.6 22.8 35.5 37.3 35.1 69.7 27.1 24.9 13.9 34.6 17.2 27.0 15.1 18.6 22.0 22.3 43.4 24.2 38.6 17.8 22.2 14.7 23.4 16.9 15.4 23.5 27.5 21.7 30.0 19.9 14.0 35.6 27.2 26.0 21.3 36.1 31.4 14.6 28.2 28.2 15.6 24.7 22.0 22.2 14.7 26.4 16.5 21.6 18.3 27.2 16.7 18.4 15.4 32.1 21.6 35.4 40.1 20.4 29.3 21.0 10.6 15.6 10.8 15.1 16.0 18.2 16.7 14.0 13.7 23.8 14.4 11.7 13.4 3.1 16.9 20.6 37.6 14.3 14.0 8.4 9.4 8.9 10.4 7.9 9.9 9.4 8.9 10.1 8.2 10.2 9.3 17.5 32.1 9.0 52.5 15.8 7.9 8.3 20.3 9.6 39.3 14.4 11.6 20.4 18.6 25.3 20.2 20.9 31.0 27.9 33.8 70.5 32.5 80.6 191.1 38.4 14.8 4.9 15.6 40.2 27.9 19.0 18.5 23.9 249.4 8.2 21.6 6.8 10.8 28.1 10.1 48.0 22.8 32.6 13.7 12.4 76.5 14.0 21.3 14.2 48.7 26.5 25.8 16.5 37.7 56.4 36.5 28.8 14.7 20.4 15.7 32.8 25.2 34.5 17.7 6.6 13.1 18.1 94.9 35.7 13.1 9.7 31.7 18.9 27.2 20.0 13.9 STXBP4 "MGC50337, Synip" ENSG00000166263 "Syntaxin binding protein 4" Q6ZWJ1 17 54968727-55173632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Astrocytes: 39.5;Cone photoreceptor cells: 41.7;Oligodendrocyte precursor cells: 84.4;Oligodendrocytes: 39.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB007760, HPA022138, HPA022888, HPA024227" Approved Approved "Plasma membrane,Cytosol" No No "Cluster 40: NK-cells - Unknown function" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Cytosol "CAB007760: AB_562350, HPA022138: AB_1857628, HPA022888: AB_1857629, HPA024227: AB_1857630" "unprognostic (5.89e-2)" "unprognostic (2.50e-2)" "unprognostic (1.30e-3)" "unprognostic (9.27e-2)" "unprognostic (1.03e-3)" "unprognostic (1.48e-1)" "unprognostic (5.00e-5)" "unprognostic (4.11e-2)" "unprognostic (1.53e-1)" "unprognostic (1.28e-2)" "unprognostic (3.45e-2)" "unprognostic (2.11e-1)" "unprognostic (1.60e-2)" "unprognostic (2.98e-2)" "unprognostic (1.65e-1)" "unprognostic (1.31e-1)" "unprognostic (1.44e-1)" 1.4 2.0 2.3 1.7 2.3 1.4 1.8 2.2 1.7 2.2 7.8 1.7 2.5 2.8 1.7 1.9 2.8 2.6 1.8 1.5 3.1 4.3 0.9 2.1 1.2 3.2 3.9 2.9 1.5 6.0 2.0 1.8 2.8 3.0 1.7 4.5 1.4 3.5 1.1 1.0 1.4 2.7 3.0 1.1 1.6 2.1 3.2 1.8 3.1 1.0 1.2 1.9 1.3 3.7 5.0 7.3 6.6 5.9 5.5 5.4 2.7 3.8 3.6 4.8 4.7 4.3 2.6 3.4 7.9 3.8 4.2 2.9 8.6 3.8 8.9 5.1 4.9 4.4 4.8 8.9 2.3 2.8 1.3 6.1 1.1 7.0 1.6 2.2 4.9 2.9 7.2 2.6 5.8 2.2 9.3 1.8 4.8 4.2 5.2 3.9 7.7 2.0 8.6 3.0 6.3 4.8 5.8 0.9 3.2 3.5 8.4 1.9 3.8 6.8 5.2 4.2 4.0 2.3 2.3 5.8 4.4 3.6 4.1 1.7 0.4 0.0 0.9 0.3 1.0 0.7 0.8 0.6 0.5 1.1 0.7 0.9 0.1 2.2 0.5 1.1 0.8 0.3 2.3 2.3 2.2 1.7 1.5 3.1 3.2 3.9 2.8 3.0 3.2 3.7 6.6 0.0 9.1 39.5 3.9 0.9 2.4 3.3 4.6 5.6 4.4 3.3 9.6 2.8 5.4 9.2 41.7 1.6 2.1 2.0 9.8 6.0 6.7 16.6 14.4 4.3 6.0 5.2 29.0 2.7 1.9 7.5 6.1 5.8 7.6 6.1 6.1 5.1 2.3 8.4 25.5 1.4 0.0 2.4 1.4 5.3 17.7 2.4 7.2 20.6 2.1 5.9 1.0 84.4 39.3 3.3 2.1 11.7 1.6 2.2 4.9 7.2 17.4 21.6 32.9 8.8 11.4 11.1 7.3 2.8 3.0 0.3 4.8 5.1 3.1 1.2 STYK1 "DKFZp761P1010, NOK, SuRTK106" ENSG00000060140 "Serine/threonine/tyrosine kinase 1" Q6J9G0 12 10618923-10674318 "Enzymes, Metabolic proteins, Predicted intracellular proteins, Predicted membrane proteins" "Kinase, Transferase, Tyrosine-protein kinase" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 17.1;stomach 1: 17.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 19.6;Excitatory neurons: 20.6;Gastric mucus-secreting cells: 15.3;Paneth cells: 12.6;Proximal enterocytes: 10.6" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.2" "Immune cell enriched" "Detected in some" 7 "NK-cell: 12.5" "Lineage enriched" "Detected in many" 7 "NK-cells: 12.5" "Cell line enhanced" "Detected in many" "CAPAN-2: 28.7;HDLM-2: 17.5;HMC-1: 18.3;HUVEC TERT2: 25.5;TIME: 23.8" "Region enhanced" "Detected in single" "basal ganglia: 2.3" "Not detected" "Not detected" "HPA040468, HPA048569" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane" Nucleoplasm "HPA040468: AB_2676998, HPA048569: AB_2680446" "unprognostic (2.30e-1)" "unprognostic (2.22e-1)" "unprognostic (1.21e-1)" "unprognostic (1.75e-1)" "unprognostic (3.11e-2)" "unprognostic (3.35e-2)" "unprognostic (6.85e-2)" "unprognostic (5.08e-3)" "unprognostic (3.37e-1)" "unprognostic (3.50e-1)" "unprognostic (2.21e-3)" "unprognostic (1.02e-1)" "unprognostic (1.70e-14)" "unprognostic (5.18e-3)" "unprognostic (1.22e-1)" "unprognostic (2.33e-1)" "unprognostic (1.45e-2)" 0.4 0.3 1.2 1.8 3.0 1.1 3.9 0.0 5.2 1.9 0.0 15.9 2.4 0.5 1.2 7.3 2.2 3.5 0.1 3.6 0.0 0.6 0.3 1.3 1.4 0.0 0.0 0.3 0.3 0.0 2.4 0.7 0.0 11.6 17.1 0.9 6.7 0.9 0.1 2.8 11.2 0.6 0.0 0.9 17.5 0.2 0.0 0.2 0.4 0.0 2.5 5.1 3.3 0.3 4.8 0.2 0.0 0.6 0.0 0.0 1.3 7.3 0.7 3.5 3.4 2.6 28.7 0.3 4.7 1.8 4.5 1.4 1.6 8.0 7.4 17.5 0.4 1.0 2.4 0.2 0.0 2.2 18.3 0.4 0.4 5.1 0.3 0.5 25.5 0.2 0.3 0.3 8.1 3.1 0.2 1.3 4.2 11.8 2.0 0.1 2.0 0.3 2.5 14.6 0.9 0.1 4.5 4.9 0.0 6.7 3.5 0.6 23.8 1.0 3.8 0.5 0.8 0.0 1.0 0.2 3.5 0.2 5.5 0.0 0.0 0.0 1.7 0.0 0.0 0.0 0.0 1.2 0.0 0.0 0.0 1.0 0.1 12.5 0.0 0.0 0.0 0.3 1.2 3.0 0.0 5.2 3.6 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 2.2 0.0 0.0 0.3 0.8 3.1 1.2 0.6 3.3 2.0 0.7 1.5 3.3 0.0 0.0 0.1 1.8 19.6 0.0 0.5 0.2 7.3 0.5 0.4 4.2 0.8 20.6 0.2 0.6 0.2 15.3 4.5 1.3 6.3 0.0 0.0 0.0 0.0 1.6 8.9 2.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.1 0.0 6.2 0.0 0.5 5.9 12.6 0.0 0.9 4.7 10.6 0.0 8.8 0.4 0.0 1.2 0.2 0.2 0.8 3.1 1.0 0.3 1.9 0.0 6.9 5.5 SUCLG2 ENSG00000172340 "Succinate-CoA ligase GDP-forming subunit beta" Q96I99 3 67360460-67654612 "Citric acid cycle related proteins, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Tricarboxylic acid cycle" Ligase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "liver: 278.0" "Cell type enhanced" "Detected in all" "Hepatocytes: 402.3;Proximal tubular cells: 354.4;Undifferentiated cells: 306.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA046705, HPA051998" Enhanced Approved "Plasma membrane,Mitochondria" NA NA 300000 "Cluster 15: NK-cells - Transcription" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 21: OE19 - Mitochondria" "Cluster 53: Intestinal epithelial cells - Unknown function" Mitochondria "Plasma membrane" "HPA046705: AB_2679762, HPA051998: AB_2681687" "unprognostic (1.69e-1)" "unprognostic (2.31e-1)" "prognostic favorable (1.08e-4)" "unprognostic (2.12e-1)" "unprognostic (3.10e-1)" "unprognostic (5.32e-2)" "unprognostic (1.87e-2)" "unprognostic (1.69e-1)" "unprognostic (3.88e-1)" "unprognostic (3.26e-2)" "unprognostic (4.61e-3)" "unprognostic (5.59e-2)" "prognostic favorable (2.79e-10)" "unprognostic (3.08e-2)" "unprognostic (2.79e-1)" "unprognostic (1.07e-1)" "unprognostic (1.38e-1)" 66.7 44.9 16.1 36.7 17.9 18.6 48.7 17.1 19.6 42.1 22.4 169.7 136.6 32.6 32.2 50.5 39.1 48.4 85.5 14.2 17.6 147.3 278.0 34.0 39.3 19.0 17.3 39.0 47.8 34.6 10.2 28.1 19.5 49.3 146.1 7.3 46.8 42.3 154.0 26.1 132.2 40.0 17.7 44.8 110.6 10.4 18.1 24.7 49.3 130.6 35.5 39.3 24.0 18.8 43.8 37.4 36.3 44.6 59.7 102.5 44.2 51.3 74.4 58.9 65.4 41.7 95.1 55.7 16.3 72.5 38.8 22.0 28.5 70.8 75.9 23.8 19.5 50.5 31.2 65.5 76.8 67.2 33.9 77.3 60.3 46.2 105.2 73.0 63.6 41.8 39.1 49.5 129.9 30.6 25.5 21.2 34.1 199.2 23.0 17.6 56.1 83.8 100.0 66.9 7.1 24.5 81.5 92.7 68.8 24.3 71.6 42.5 55.9 58.2 38.2 64.5 61.8 33.4 52.2 39.0 85.5 51.6 70.0 17.3 36.3 13.0 30.8 44.3 37.6 45.5 44.6 39.5 24.6 42.5 68.4 53.1 1.6 68.0 37.4 9.8 45.4 48.5 16.1 17.9 17.1 19.6 14.2 17.6 19.0 17.3 19.5 17.7 18.1 18.8 40.2 35.3 50.8 66.6 48.5 37.1 44.7 38.9 21.1 2.9 54.1 29.1 172.0 84.4 51.7 80.9 8.4 55.4 31.7 223.5 244.6 85.1 3.2 49.6 43.4 40.1 58.2 17.2 6.2 80.9 44.9 47.5 90.7 46.8 30.4 31.4 45.0 402.3 56.5 5.0 5.3 212.1 40.7 68.6 49.2 5.4 41.3 36.3 42.7 90.9 35.5 29.2 36.0 72.4 60.0 59.2 164.0 47.4 30.3 41.2 222.2 354.4 58.7 4.5 32.9 41.6 50.5 1.6 6.3 55.6 49.3 38.0 48.6 78.5 306.6 50.9 SUMF2 DKFZp566I1024 ENSG00000129103 "Sulfatase modifying factor 2" Q8NBJ7 7 56064002-56080670 "Plasma proteins, Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA024040, CAB025743, HPA074892" Enhanced Uncertain "Vesicles,Plasma membrane" "Intracellular and membrane" Yes No 750000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 50: Fibroblasts - ECM organization" "Vesicles, Plasma membrane" "CAB025743: , HPA024040: AB_1857651, HPA074892: " "unprognostic (2.93e-1)" "prognostic unfavorable (6.58e-6)" "unprognostic (2.42e-2)" "prognostic favorable (3.96e-4)" "unprognostic (3.87e-2)" "unprognostic (9.11e-3)" "unprognostic (1.69e-2)" "unprognostic (1.19e-1)" "unprognostic (1.41e-1)" "unprognostic (7.20e-2)" "unprognostic (1.92e-1)" "unprognostic (7.26e-2)" "unprognostic (1.74e-1)" "unprognostic (1.74e-2)" "unprognostic (2.64e-1)" "unprognostic (1.99e-3)" "prognostic unfavorable (7.71e-4)" 64.1 64.6 26.1 43.0 29.7 51.5 57.5 29.3 27.1 91.3 45.0 67.4 89.2 57.5 64.8 46.8 102.6 70.6 30.8 25.1 27.8 93.4 94.8 71.6 50.2 35.2 29.6 59.7 91.8 115.8 31.8 45.5 33.4 79.3 69.1 11.0 69.5 77.1 22.4 47.5 74.4 57.7 29.9 57.0 92.7 23.7 30.8 57.6 91.2 21.4 51.3 57.2 43.6 35.9 352.3 102.9 46.0 211.8 214.4 147.5 68.9 114.5 156.1 92.6 114.5 57.2 278.0 57.1 96.5 162.4 90.4 172.3 27.4 131.3 61.1 90.6 42.9 36.4 63.5 54.2 138.4 89.7 108.7 116.8 124.5 83.7 143.3 186.9 137.7 101.4 116.4 236.6 151.3 76.8 77.2 115.7 63.5 272.0 52.2 61.5 45.4 359.0 127.7 39.1 54.0 65.6 142.4 294.2 140.9 98.9 294.5 144.5 115.2 85.6 121.1 211.1 98.6 160.8 130.8 84.0 139.7 165.7 283.2 58.1 60.3 22.0 71.1 80.5 90.9 59.8 70.9 71.8 72.3 49.1 75.3 75.2 4.4 49.0 90.3 132.6 82.7 90.2 26.1 29.7 29.3 27.1 25.1 27.8 35.2 29.6 33.4 29.9 30.8 35.9 44.0 57.7 30.5 20.5 47.3 33.8 44.1 46.1 39.9 25.7 57.9 25.4 10.4 87.2 31.0 90.1 14.6 44.5 85.3 45.1 19.6 95.3 3.8 93.1 70.2 43.7 59.3 41.7 21.2 55.7 96.7 54.7 55.5 78.9 54.5 47.0 51.0 91.3 68.1 43.7 24.4 61.8 22.4 79.8 38.7 8.0 69.6 50.4 53.4 14.0 73.0 23.8 70.0 10.6 24.2 48.4 64.6 47.4 65.0 50.7 91.8 45.6 34.5 13.5 52.6 41.6 44.1 31.6 28.6 52.8 41.9 46.7 52.7 58.7 85.8 42.7 SWAP70 "KIAA0640, SWAP-70" ENSG00000133789 "Switching B cell complex subunit SWAP70" Q9UH65 11 9664077-9752993 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "B-cells: 183.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "memory B-cell: 80.6;naive B-cell: 84.8" "Group enriched" "Detected in all" 7 "B-cells: 84.8;granulocytes: 48.6;monocytes: 29.6" "Cell line enhanced" "Detected in many" "Daudi: 161.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006810, HPA006929" Supported Supported "Plasma membrane,Actin filaments" NA NA 21000 "Cluster 19: B-cells - Humoral immune response" "Cluster 16: Immune cells - Immune response" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 57: B-cells - Immune response" "Plasma membrane" "Actin filaments" "HPA006810: AB_1857683, HPA006929: " "unprognostic (4.16e-2)" "unprognostic (7.06e-2)" "unprognostic (2.35e-1)" "unprognostic (3.68e-2)" "unprognostic (1.67e-1)" "unprognostic (3.38e-2)" "unprognostic (3.16e-3)" "unprognostic (1.26e-1)" "unprognostic (4.04e-1)" "unprognostic (3.33e-1)" "unprognostic (1.75e-1)" "unprognostic (3.85e-2)" "unprognostic (2.79e-3)" "unprognostic (5.00e-2)" "unprognostic (1.14e-1)" "unprognostic (3.61e-1)" "unprognostic (1.44e-1)" 39.3 10.4 12.8 37.5 13.7 20.9 31.9 13.6 15.9 22.6 17.2 15.0 15.4 17.8 10.4 17.8 16.3 22.0 16.2 12.2 14.1 17.2 10.0 24.9 66.1 16.7 13.6 10.2 15.0 19.4 5.7 39.0 16.7 14.1 12.8 3.9 18.0 15.3 9.8 26.4 20.3 19.7 16.5 59.5 15.9 4.8 14.3 17.3 22.3 14.7 75.3 31.2 17.6 16.5 40.6 22.2 30.8 0.1 62.9 54.6 54.0 43.4 52.6 40.3 44.1 24.7 31.3 161.0 41.6 83.5 57.9 47.7 37.9 24.2 51.6 14.8 15.2 42.6 25.7 12.1 35.2 33.3 76.2 38.4 29.6 29.5 52.3 32.6 124.4 20.2 3.9 0.6 42.4 6.4 10.0 16.1 28.4 10.7 11.3 23.6 28.9 4.7 33.6 106.1 1.5 15.5 41.3 52.6 35.2 42.9 20.9 25.1 143.6 70.3 25.1 59.4 41.2 4.2 12.4 111.5 27.9 36.6 29.3 19.7 5.7 48.6 1.2 13.5 0.5 80.6 1.4 1.1 8.2 84.8 1.2 1.3 1.1 7.9 29.6 2.3 4.2 5.4 12.8 13.7 13.6 15.9 12.2 14.1 16.7 13.6 16.7 16.5 14.3 16.5 154.0 67.3 60.8 33.0 183.7 35.6 68.1 40.1 36.5 3.4 35.1 28.3 17.6 22.8 57.7 20.2 0.0 82.6 9.9 11.3 13.7 47.4 1.6 66.5 18.6 136.0 13.1 9.7 9.0 21.6 128.0 39.1 15.8 71.6 137.8 10.3 53.2 7.2 65.0 26.9 14.5 8.7 18.3 61.9 50.8 2.9 29.8 58.5 28.4 77.8 88.8 9.2 6.2 22.1 22.4 37.0 15.1 34.6 20.7 63.0 22.4 11.7 50.9 2.3 19.7 46.2 35.5 5.5 10.8 17.4 31.3 140.1 15.5 33.4 9.0 78.8 SYPL2 Mg29 ENSG00000143028 "Synaptophysin like 2" Q5VXT5 1 109466546-109482134 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "skeletal muscle: 363.5;tongue: 175.3" "Cell type enhanced" "Detected in some" "Astrocytes: 5.5;Cardiomyocytes: 10.6;Collecting duct cells: 3.7;Hepatocytes: 4.8;Late spermatids: 11.1;Proximal tubular cells: 5.1;Skeletal myocytes: 4.8" "Cancer enhanced" "Detected in many" "renal cancer: 3.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "ASC diff: 31.6;ASC TERT1: 13.2;BJ: 14.1;BJ hTERT+: 44.1;fHDF/TERT166: 23.1;HAP1: 11.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA076657 Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 37: Myocytes - Muscle contraction" Cytosol "Plasma membrane" "HPA076657: " "unprognostic (1.82e-2)" "unprognostic (1.81e-1)" "unprognostic (2.90e-4)" "unprognostic (6.63e-2)" "unprognostic (1.35e-1)" "unprognostic (9.36e-3)" "unprognostic (2.84e-2)" "unprognostic (2.57e-1)" "unprognostic (2.35e-1)" "unprognostic (3.11e-1)" "unprognostic (2.34e-1)" "unprognostic (1.08e-1)" "prognostic favorable (3.05e-4)" "unprognostic (2.54e-3)" "unprognostic (3.40e-1)" "unprognostic (9.46e-3)" "unprognostic (6.39e-4)" 2.8 11.7 1.5 0.6 1.5 0.0 1.5 1.3 2.4 4.0 4.0 6.2 0.5 6.6 4.5 4.6 1.4 0.9 19.9 1.6 1.3 9.6 9.5 1.3 0.5 1.4 1.3 3.0 5.1 5.8 1.1 3.2 1.2 3.1 1.0 0.4 4.2 6.0 363.5 0.7 1.6 6.0 1.0 1.1 3.2 9.3 1.6 0.1 8.0 175.3 0.3 4.1 2.4 1.3 0.0 0.1 0.1 1.8 31.6 13.2 0.0 14.1 44.1 4.3 1.6 0.0 0.1 0.0 0.0 23.1 0.5 0.0 11.8 0.0 0.9 0.0 5.1 0.0 0.4 0.2 0.6 0.0 1.1 1.2 0.0 0.3 0.0 0.3 0.0 0.0 0.5 0.0 0.2 0.0 0.0 0.0 1.4 0.0 0.1 0.0 0.6 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.1 0.1 0.0 1.4 3.3 2.3 0.7 0.0 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 1.5 1.3 2.4 1.6 1.3 1.4 1.3 1.2 1.0 1.6 1.3 0.2 0.0 0.0 5.5 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.3 10.6 0.0 0.0 3.7 0.0 0.1 0.0 0.0 0.0 0.2 2.8 0.0 0.1 0.4 0.0 0.0 0.3 1.3 0.0 1.0 0.0 0.0 0.0 0.9 0.0 4.8 0.1 0.0 0.1 0.0 0.0 0.0 0.0 11.1 0.0 0.1 0.0 1.0 0.0 1.1 0.0 0.0 0.1 0.1 0.0 0.7 0.0 0.1 0.0 5.1 0.0 0.0 0.0 4.8 2.6 0.4 1.4 0.0 0.0 0.1 0.2 0.4 0.0 0.0 SYT4 "HsT1192, KIAA1342" ENSG00000132872 "Synaptotagmin 4" Q9H2B2 18 43267892-43277535 "Predicted intracellular proteins" Differentiation "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 74.7;pituitary gland: 30.7;retina: 25.2" "Cell type enhanced" "Detected in some" "Bipolar cells: 66.8;Cone photoreceptor cells: 22.9;Enteroendocrine cells: 28.7;Excitatory neurons: 50.9;Fibroblasts: 23.0;Inhibitory neurons: 34.1" "Group enriched" "Detected in some" 5 "glioma: 2.0;pancreatic cancer: 4.1;prostate cancer: 1.2" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 11 "SH-SY5Y: 245.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA010574 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 69: Cerebellum - Gene expression regulation" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 56: Bipolar cells - Visual perception" "Vesicles, Plasma membrane" "HPA010574: AB_2668309" "unprognostic (2.91e-3)" "unprognostic (2.03e-1)" "unprognostic (2.37e-2)" "unprognostic (2.87e-1)" "unprognostic (7.67e-3)" "unprognostic (5.30e-3)" "unprognostic (3.95e-2)" "unprognostic (1.23e-3)" "unprognostic (3.61e-1)" "unprognostic (3.80e-2)" 3.7 15.9 21.5 1.4 18.6 0.1 0.0 74.7 42.6 0.0 0.0 1.2 0.8 0.0 0.0 0.1 0.0 0.0 1.3 18.6 50.4 0.1 0.0 0.9 0.0 10.5 15.3 0.5 3.7 0.0 30.7 0.1 39.3 0.6 0.8 25.2 0.1 8.3 0.0 0.0 0.7 0.6 13.5 0.0 3.2 1.6 18.3 0.4 0.3 0.0 0.0 0.0 0.5 10.9 0.0 0.0 0.8 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.4 245.6 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 21.5 18.6 74.7 42.6 18.6 50.4 10.5 15.3 39.3 13.5 18.3 10.9 0.0 0.0 1.1 8.8 0.0 0.1 0.0 0.0 0.0 66.8 0.0 0.0 3.6 0.0 2.5 0.0 22.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.5 28.7 0.0 50.9 0.0 0.0 23.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 1.7 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 9.4 0.0 2.5 0.0 7.5 7.6 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.7 10.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.2 4.9 0.0 0.1 TBC1D24 "DFNA65, DFNB86, KIAA1171, TLDC6" ENSG00000162065 "TBC1 domain family member 24" Q9ULP9 16 2475051-2509560 "Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" "GTPase activation" "Deafness, Disease variant, Epilepsy, Mental retardation, Non-syndromic deafness" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "salivary gland: 16.5" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 43.8;Inhibitory neurons: 34.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "SCLC-21H: 34.7" "HPA044712, HPA068080" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 30: Mammary glandular cells - Lactation" "Plasma membrane, Cell Junctions" "HPA044712: AB_10795619, HPA068080: AB_2685948" "prognostic unfavorable (3.22e-4)" "unprognostic (5.23e-2)" "unprognostic (4.02e-2)" "unprognostic (6.41e-2)" "unprognostic (3.52e-1)" "unprognostic (1.52e-2)" "unprognostic (1.40e-1)" "unprognostic (2.03e-2)" "unprognostic (1.68e-1)" "unprognostic (7.37e-2)" "unprognostic (4.37e-2)" "unprognostic (1.28e-1)" "unprognostic (4.66e-3)" "unprognostic (2.02e-2)" "unprognostic (8.19e-2)" "unprognostic (7.78e-3)" "unprognostic (1.61e-1)" 3.8 3.3 7.5 1.8 8.1 2.5 2.8 3.6 10.5 2.1 0.0 2.0 2.2 1.4 2.8 1.0 2.3 1.9 3.0 8.3 3.7 4.3 3.7 3.9 1.8 2.9 2.9 1.0 10.6 1.9 2.6 2.1 3.1 2.5 0.9 4.2 16.5 3.5 3.4 1.2 1.6 1.7 1.9 2.0 2.2 1.2 4.4 0.9 3.1 1.7 1.2 1.8 0.9 2.8 3.4 6.7 4.5 9.2 5.1 5.1 3.8 6.2 3.3 4.0 3.5 6.2 2.9 8.6 5.2 4.9 1.9 6.3 7.1 2.0 2.9 9.3 8.0 8.0 9.5 5.5 3.1 5.9 3.2 1.9 2.8 3.5 1.4 2.8 5.1 3.3 9.9 4.8 3.8 6.4 4.1 11.9 4.0 3.2 4.3 20.9 8.5 6.1 2.9 2.3 34.7 8.5 3.8 15.3 2.6 1.6 4.8 5.2 5.4 7.8 8.4 7.9 6.2 3.2 3.0 11.0 3.4 8.5 7.2 0.0 0.1 0.0 0.3 0.1 0.1 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 7.5 8.1 3.6 10.5 8.3 3.7 2.9 2.9 3.1 1.9 4.4 2.8 4.7 28.9 26.7 15.7 1.9 0.5 3.0 1.4 1.8 19.0 17.8 10.8 6.9 10.0 6.9 5.5 43.8 1.5 5.6 2.4 33.2 5.0 0.2 2.8 10.0 5.4 11.4 6.5 29.6 6.1 1.0 5.8 5.6 4.0 3.8 6.0 10.4 17.3 3.5 26.9 34.0 2.6 6.1 5.1 3.3 1.0 9.0 3.0 1.8 6.5 3.6 13.8 6.2 25.1 9.7 5.0 2.8 6.0 1.7 3.1 1.8 3.9 3.6 25.5 0.0 11.2 3.7 8.8 5.9 1.4 1.4 0.3 2.9 3.4 4.7 1.6 TBC1D30 KIAA0984 ENSG00000111490 "TBC1 domain family member 30" Q9Y2I9 12 64759484-64881033 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 10.1;pancreas: 12.0" "Cell type enhanced" "Detected in many" "Excitatory neurons: 30.9;Inhibitory neurons: 42.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "MCF7: 25.9;OE19: 11.9;RPMI-8226: 12.6;RT4: 12.8;SCLC-21H: 26.5;SK-BR-3: 16.7;T-47d: 14.5" "HPA039772, HPA040043" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 22: Non-specific - Unknown function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" "Plasma membrane" Cytosol "HPA039772: AB_10795409, HPA040043: AB_10795411" "unprognostic (1.85e-1)" "unprognostic (6.95e-2)" "unprognostic (2.66e-1)" "prognostic favorable (3.61e-5)" "unprognostic (9.35e-2)" "unprognostic (2.09e-1)" "unprognostic (2.65e-5)" "prognostic favorable (5.08e-4)" "unprognostic (1.75e-3)" "unprognostic (2.16e-2)" "unprognostic (2.44e-1)" "unprognostic (9.72e-2)" "unprognostic (7.32e-2)" "unprognostic (7.62e-3)" "unprognostic (8.72e-2)" "unprognostic (2.67e-3)" "unprognostic (7.80e-3)" 1.5 1.1 2.0 1.0 2.7 0.3 2.3 4.9 10.1 3.0 1.4 1.4 1.8 1.4 1.8 0.6 1.5 1.8 0.6 5.3 1.7 2.2 1.2 2.3 0.4 6.8 1.8 0.9 12.0 2.4 6.4 0.6 6.9 3.0 1.5 2.2 6.8 2.7 0.3 0.8 1.6 0.9 2.0 1.9 3.9 1.9 2.0 0.3 1.5 0.3 0.3 3.3 1.3 3.8 5.1 1.0 0.5 0.3 0.1 0.6 0.7 0.0 0.0 0.1 0.0 4.3 1.8 0.1 0.9 0.1 0.3 0.1 5.3 0.2 0.0 0.0 3.8 0.3 1.4 0.1 0.0 4.0 0.8 0.3 0.1 0.0 0.0 0.6 3.8 1.2 0.0 2.0 0.3 25.9 0.0 0.6 1.1 11.9 5.2 0.2 0.1 12.6 0.9 12.8 26.5 1.8 1.4 16.7 0.3 0.3 14.5 1.4 4.2 0.0 0.9 0.9 2.5 0.0 0.0 0.1 0.1 0.4 0.4 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.1 0.0 0.0 0.0 2.0 2.7 4.9 10.1 5.3 1.7 6.8 1.8 6.9 2.0 2.0 3.8 5.1 0.0 6.3 4.9 0.6 0.9 4.6 0.9 0.0 9.3 7.2 3.8 0.6 5.7 4.5 3.7 8.4 0.7 1.5 2.5 9.8 3.9 14.2 2.2 0.8 6.5 0.0 0.0 30.9 4.9 0.3 0.7 3.6 4.2 8.9 0.8 1.8 0.3 1.6 0.0 42.8 6.4 6.1 4.0 6.2 1.9 0.3 3.0 5.4 12.2 1.2 2.6 0.0 1.5 2.0 2.7 4.9 0.0 0.6 9.1 3.9 2.3 1.8 0.6 0.0 0.6 1.0 3.7 3.0 0.3 1.4 0.1 0.8 0.4 4.4 8.7 TBXA2R ENSG00000006638 "Thromboxane A2 receptor" P21731 19 3594507-3606875 "Disease related genes, G-protein coupled receptors, Human disease related genes, Predicted membrane proteins" "G-protein coupled receptor, Receptor, Transducer" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in some" 6 "Adipocytes: 10.8;Endothelial cells: 8.7;Hepatic stellate cells: 30.7;Macrophages: 19.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "naive B-cell: 11.1" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HeLa: 9.5;U-2197: 6.8;U-937: 6.1" "Low region specificity" "Detected in single" "Low region specificity" "Detected in all" HPA077366 Supported "Nuclear speckles,Plasma membrane" NA NA "Cluster 21: B-cells - Adaptive immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 18: U-2197 - ECM organization" "Cluster 51: Myeloid cells - Hemostasis" "Plasma membrane" "Nuclear speckles" "HPA077366: AB_2686836" "unprognostic (1.59e-1)" "unprognostic (3.86e-2)" "unprognostic (1.21e-2)" "unprognostic (1.74e-1)" "unprognostic (8.97e-2)" "unprognostic (4.19e-2)" "unprognostic (1.52e-2)" "unprognostic (2.17e-3)" "unprognostic (8.41e-2)" "unprognostic (6.25e-2)" "prognostic favorable (7.17e-4)" "unprognostic (3.89e-2)" "prognostic unfavorable (1.45e-4)" "unprognostic (4.32e-2)" "unprognostic (9.63e-2)" "unprognostic (1.76e-1)" "unprognostic (2.02e-1)" 3.8 8.7 1.3 1.6 1.1 1.0 1.9 1.8 1.3 5.4 1.3 2.3 0.8 5.2 0.4 1.7 3.3 1.0 5.0 1.1 1.1 6.3 6.1 4.4 1.0 1.7 1.3 2.0 0.9 1.2 1.0 3.2 1.5 2.5 0.4 0.5 0.6 1.4 1.4 1.1 3.2 1.8 1.1 7.0 2.5 0.6 1.4 0.3 2.6 0.6 0.3 2.6 3.6 2.1 0.2 0.2 0.3 3.4 0.7 1.7 0.5 2.4 0.6 1.8 1.4 0.1 0.3 0.1 3.5 1.0 1.8 0.2 0.7 0.0 0.7 0.2 0.8 2.3 9.5 0.2 0.9 0.2 4.1 0.8 0.0 2.4 0.0 1.4 0.7 0.1 3.8 0.4 0.3 0.1 0.2 1.2 0.3 0.1 2.1 0.1 0.0 0.1 0.0 0.1 0.1 1.3 0.2 0.4 0.1 0.3 1.5 4.2 2.1 3.8 0.8 6.8 2.3 0.2 0.3 0.2 3.1 6.1 0.9 3.7 0.4 0.4 2.5 0.2 0.3 2.0 0.7 2.2 0.1 11.1 4.3 9.4 4.1 3.3 0.3 0.3 0.2 4.0 1.3 1.1 1.8 1.3 1.1 1.1 1.7 1.3 1.5 1.1 1.4 2.1 10.8 0.0 0.0 0.0 2.6 0.5 0.1 0.0 0.0 0.3 0.1 0.1 1.3 0.0 0.0 1.8 0.0 0.1 0.4 0.0 0.0 0.1 0.0 0.1 0.6 8.7 0.0 0.0 0.3 0.0 0.2 2.3 0.0 0.1 0.0 0.2 30.7 0.6 0.9 0.0 0.9 0.0 0.0 1.0 0.3 0.0 0.3 19.2 1.8 1.9 0.3 0.5 1.0 0.5 0.4 0.1 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.4 2.5 0.4 1.9 0.1 0.6 0.1 0.8 0.4 0.1 0.0 TCAF2 "FAM115C, FAM139A, FLJ40722, GATD9" ENSG00000170379 "TRPM8 channel associated factor 2" A6NFQ2 7 143620952-143730409 "Predicted intracellular proteins" Transport "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 16.2;Hepatocytes: 12.3;Syncytiotrophoblasts: 15.7;T-cells: 9.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HDLM-2: 10.6;HUVEC TERT2: 11.6;TIME: 18.5;U-87 MG: 13.8" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 11: Squamous epithelial cells - Epithelial cell function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 58: T-cells - T-cell receptor" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" "unprognostic (6.59e-2)" "unprognostic (4.99e-2)" "unprognostic (2.34e-2)" "unprognostic (8.86e-3)" "prognostic unfavorable (9.53e-5)" "unprognostic (1.89e-1)" "unprognostic (3.11e-2)" "unprognostic (4.47e-2)" "unprognostic (2.36e-1)" "unprognostic (2.04e-2)" "unprognostic (3.98e-2)" "unprognostic (2.21e-2)" "prognostic unfavorable (4.17e-6)" "unprognostic (7.19e-2)" "unprognostic (4.02e-2)" "unprognostic (5.41e-3)" "unprognostic (2.85e-2)" 2.1 1.9 1.5 4.0 1.5 4.1 5.8 4.6 3.4 4.0 0.0 1.2 1.0 1.7 0.8 9.2 1.9 2.2 1.2 1.5 1.9 2.6 4.5 3.7 4.2 2.2 2.5 2.6 2.0 2.1 2.6 5.2 2.5 2.8 1.1 3.2 3.7 1.2 0.7 4.3 2.4 1.5 0.7 2.8 2.0 1.6 1.7 3.3 1.3 0.7 3.4 2.8 5.9 3.2 5.5 0.3 0.1 0.2 1.0 1.0 2.0 1.5 3.1 0.7 2.2 0.1 0.3 0.2 2.1 1.3 0.5 0.8 0.1 3.0 2.3 10.6 0.5 0.8 0.6 0.1 1.2 0.3 0.4 2.9 1.3 0.3 0.9 2.1 11.6 0.7 3.0 5.1 4.3 0.8 0.6 0.8 0.2 5.0 2.7 0.4 2.1 2.4 0.0 1.9 0.1 0.1 0.5 4.3 0.2 0.8 1.9 0.2 18.5 1.3 0.9 5.5 0.4 7.7 2.6 0.1 13.8 0.4 3.2 5.7 0.2 0.2 2.9 0.2 3.1 1.9 4.8 3.1 0.2 1.8 4.2 3.3 0.9 2.2 0.2 0.7 5.6 1.2 1.5 1.5 4.6 3.4 1.5 1.9 2.2 2.5 2.5 0.7 1.7 3.2 0.5 0.0 1.8 0.0 4.5 0.0 1.3 0.0 3.4 0.7 5.6 3.4 0.4 0.0 1.8 0.0 0.0 16.2 5.6 0.2 0.0 0.9 1.0 0.8 1.4 3.5 0.0 0.4 3.7 0.4 4.9 2.4 2.6 1.3 2.5 0.3 0.7 12.3 2.0 0.0 3.6 0.2 0.0 1.6 0.0 1.1 1.8 1.8 0.0 0.0 0.4 2.1 7.2 1.5 0.1 1.3 0.1 0.7 5.0 2.1 2.1 0.4 0.0 0.1 0.0 2.3 1.1 3.5 2.0 4.9 0.0 15.7 9.1 0.8 0.4 1.1 TCAF2C ENSG00000283528 "TRPM8 channel associated factor 2C" 7 143639230-143647646 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Not detected" "Not detected" "Low region specificity" "Detected in single" "HPA038756, HPA038758" Uncertain Supported "Plasma membrane,Cell Junctions" NA NA "Cluster 35: T-regs - Unknown function" "Plasma membrane, Cell Junctions" "HPA038756: AB_10960427, HPA038758: AB_10960353" 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.8 0.0 0.0 0.0 0.0 0.8 0.4 0.0 0.0 0.0 0.0 2.0 0.0 0.0 0.7 0.0 0.5 0.3 0.8 0.4 0.0 0.3 0.5 0.5 0.0 0.7 0.0 0.0 2.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 TDG ENSG00000139372 "Thymine DNA glycosylase" Q13569 12 103965822-103988874 "Enzymes, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" "Activator, Chromatin regulator, Hydrolase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA052263 Supported Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 65: Plasmacytoid DCs - Unknown function" Nucleoplasm "Plasma membrane" "HPA052263: AB_2681777" "unprognostic (3.15e-1)" "unprognostic (1.36e-1)" "unprognostic (9.89e-3)" "unprognostic (6.93e-2)" "unprognostic (3.66e-2)" "unprognostic (1.13e-1)" "prognostic unfavorable (6.27e-5)" "unprognostic (1.56e-2)" "prognostic unfavorable (6.90e-5)" "unprognostic (5.37e-2)" "unprognostic (1.82e-1)" "unprognostic (8.48e-2)" "prognostic unfavorable (1.90e-10)" "unprognostic (3.68e-1)" "unprognostic (2.90e-1)" "unprognostic (1.11e-1)" "unprognostic (1.16e-1)" 10.8 13.6 5.8 15.9 6.4 18.1 12.0 6.7 7.2 10.0 7.2 13.2 11.4 11.6 9.5 17.8 8.7 12.2 9.8 6.3 6.0 8.5 12.1 9.6 21.0 5.3 5.5 9.7 9.5 10.4 9.5 17.5 5.5 9.6 15.6 10.5 9.2 7.3 9.5 12.8 13.4 10.9 4.6 11.9 11.2 4.9 5.5 25.7 10.6 9.6 19.1 17.1 11.2 7.3 42.6 21.4 64.4 37.2 15.5 13.7 69.4 32.4 12.3 42.6 23.6 39.1 18.2 99.4 18.8 26.3 6.9 27.9 76.8 36.5 32.6 42.8 66.8 76.4 31.8 17.5 14.8 95.4 55.8 16.3 48.0 31.5 24.6 25.9 42.3 58.4 91.1 15.8 20.6 45.2 107.6 53.6 76.7 33.0 34.0 107.9 32.8 35.0 46.4 61.4 84.2 58.0 38.9 42.7 28.4 37.7 70.7 52.2 26.5 13.3 21.5 14.3 37.5 34.5 49.5 81.8 14.2 52.0 25.3 55.0 53.0 45.8 28.9 39.2 22.0 43.4 28.1 24.3 34.6 39.8 28.5 25.5 35.5 33.6 40.1 92.5 30.5 17.6 5.8 6.4 6.7 7.2 6.3 6.0 5.3 5.5 5.5 4.6 5.5 7.3 35.4 38.5 23.8 12.1 54.6 79.0 49.1 63.0 38.7 51.3 61.2 54.9 25.9 37.1 49.4 33.1 27.1 66.7 68.7 35.2 37.2 68.6 6.2 44.7 44.7 45.2 81.7 69.4 30.3 53.9 82.6 38.5 47.4 45.7 40.4 27.0 39.3 36.4 44.1 35.3 30.0 55.7 87.5 44.8 42.1 3.8 27.4 42.4 16.0 23.4 41.1 24.4 43.3 20.6 20.9 79.7 39.0 30.1 52.6 52.4 28.4 30.5 40.8 39.0 46.0 37.4 38.0 11.0 23.1 52.8 102.9 156.7 49.8 25.0 42.6 61.8 TDO2 "TDO, TPH2" ENSG00000151790 "Tryptophan 2,3-dioxygenase" P48775 4 155854738-155920406 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Tryptophan catabolism" "Dioxygenase, Oxidoreductase" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 47 "liver: 797.8" "Cell type enriched" "Detected in some" 7 "Hepatocytes: 1174.2" "Cancer enriched" "Detected in many" 18 "liver cancer: 35.7" "Low region specificity" "Detected in some" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "EFO-21: 9.6;HDLM-2: 22.0;U-87 MG: 11.3" "Group enriched" "Detected in some" 7 "cerebellum: 6.3;hippocampal formation: 5.3;white matter: 1.9" "Low region specificity" "Detected in all" HPA039611 Uncertain Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 60: Liver - Hemostasis & Lipid metabolism" "Cluster 44: HDLM-2 - Immune response" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane, Cytosol" "HPA039611: " "unprognostic (1.10e-1)" "unprognostic (3.00e-3)" "unprognostic (3.84e-2)" "unprognostic (1.95e-1)" "unprognostic (7.06e-2)" "unprognostic (3.50e-1)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (1.00e-1)" "unprognostic (2.13e-2)" "unprognostic (1.42e-1)" "unprognostic (1.01e-1)" "unprognostic (4.68e-8)" "unprognostic (7.99e-2)" "unprognostic (9.29e-3)" "unprognostic (1.28e-1)" "unprognostic (1.95e-2)" 0.3 1.6 0.3 16.8 0.5 0.0 0.1 0.2 1.2 0.2 0.2 1.2 3.5 0.4 0.6 0.7 0.3 1.9 0.0 0.5 0.3 0.6 797.8 3.2 3.1 0.2 1.1 0.1 0.3 0.1 4.0 0.6 0.2 0.2 1.4 0.0 0.4 0.2 0.2 0.0 5.9 2.5 0.3 1.9 1.6 0.4 0.3 0.2 0.2 0.0 2.6 7.6 0.1 0.7 0.0 1.9 0.0 0.0 0.1 0.0 0.0 0.0 1.6 0.0 0.0 0.1 0.0 0.0 9.6 0.0 0.2 0.0 0.1 0.0 0.0 22.0 0.0 0.1 0.0 0.0 0.3 0.3 0.0 1.1 0.0 0.0 0.0 0.9 0.0 0.0 0.1 3.5 0.3 0.0 0.0 0.0 0.9 0.0 0.0 0.0 0.2 1.6 0.0 0.3 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.2 0.0 1.2 0.4 0.5 0.0 3.4 0.0 0.0 11.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.5 0.2 1.2 0.5 0.3 0.2 1.1 0.2 0.3 0.3 0.7 0.8 0.0 0.0 0.7 2.7 0.0 0.1 0.0 0.0 0.0 0.1 0.3 0.6 158.7 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.9 0.5 0.1 1.1 2.4 0.0 32.0 4.1 0.0 0.0 1.7 3.6 0.1 0.0 0.0 29.6 1174.2 0.9 0.0 0.4 0.0 0.0 31.7 0.0 0.3 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 6.6 0.0 11.3 0.4 1.1 0.0 0.0 0.3 2.3 0.3 0.0 0.1 TDP1 "FLJ11090, SCAN1" ENSG00000042088 "Tyrosyl-DNA phosphodiesterase 1" Q9NUW8 14 89954939-90044764 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "DNA damage, DNA repair" "Exonuclease, Hydrolase, Nuclease" "Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 123.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071317 Approved Supported "Nucleoplasm,Plasma membrane" No No "Cluster 44: Non-specific - Transcription" "Cluster 3: T-cells - Adaptive immune response" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 23: Spermatids - Flagellum & Golgi organization" Nucleoplasm "Plasma membrane" "HPA071317: AB_2686388" "unprognostic (5.60e-3)" "unprognostic (3.53e-1)" "unprognostic (7.03e-3)" "unprognostic (1.34e-1)" "unprognostic (7.45e-2)" "unprognostic (7.22e-2)" "prognostic unfavorable (8.99e-5)" "unprognostic (2.61e-1)" "unprognostic (1.46e-2)" "unprognostic (5.84e-3)" "unprognostic (2.51e-1)" "unprognostic (6.46e-2)" "unprognostic (1.10e-1)" "unprognostic (3.41e-1)" "unprognostic (1.64e-1)" "unprognostic (2.91e-2)" "unprognostic (1.26e-1)" 5.5 3.9 4.8 11.8 4.5 13.9 8.9 6.6 4.9 6.6 7.1 7.8 6.5 5.9 5.8 8.2 9.2 6.6 2.6 4.1 5.3 7.0 6.5 4.7 19.0 3.8 3.6 6.4 4.8 5.1 4.6 8.2 3.9 5.0 10.1 4.9 5.5 4.3 2.1 6.4 7.0 6.3 2.8 10.6 7.9 22.3 4.6 28.3 4.9 1.7 23.7 8.1 5.0 4.2 33.8 18.6 40.9 37.5 10.1 14.0 32.7 31.7 25.9 38.4 34.6 13.6 35.5 42.9 23.3 21.7 12.9 33.9 18.2 29.5 55.2 44.1 19.6 43.9 16.7 16.6 8.7 73.2 24.1 10.1 12.9 26.9 24.9 21.9 49.5 57.3 30.6 43.5 45.9 35.0 56.3 39.2 10.0 39.8 43.7 42.3 77.3 34.0 24.6 27.3 30.7 20.9 26.9 77.6 10.1 27.0 31.0 30.8 39.9 16.5 15.7 23.0 28.7 31.8 60.4 52.3 35.5 32.3 24.6 28.7 8.9 15.1 18.8 14.6 18.3 21.1 19.8 20.8 14.2 20.0 21.7 23.1 5.7 23.8 14.1 15.0 32.2 14.8 4.8 4.5 6.6 4.9 4.1 5.3 3.8 3.6 3.9 2.8 4.6 4.2 2.9 0.0 1.1 4.2 15.2 4.7 4.9 7.4 4.0 3.0 6.4 7.1 1.4 1.5 5.0 14.7 8.4 11.4 14.6 3.8 5.9 9.2 123.5 13.2 6.1 3.6 3.6 12.8 13.4 5.6 14.9 4.3 7.7 9.2 2.5 8.9 3.9 4.2 8.8 3.3 13.9 4.9 0.0 6.8 10.2 36.7 2.8 7.8 1.8 1.9 8.0 1.5 8.2 8.0 24.2 6.4 4.8 3.0 16.9 5.7 2.9 7.8 11.0 2.7 0.0 3.4 5.4 33.7 22.8 8.7 4.5 10.1 15.0 10.3 7.9 4.0 TEK "CD202b, TIE-2, TIE2, VMCM, VMCM1" ENSG00000120156 "TEK receptor tyrosine kinase" Q02763 9 27109141-27230174 "Cancer-related genes, CD markers, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted membrane proteins, Predicted secreted proteins, RAS pathway related proteins" Angiogenesis "Kinase, Receptor, Transferase, Tyrosine-protein kinase" "Cancer-related genes, Disease variant, FDA approved drug targets, Glaucoma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "placenta: 46.3" "Group enriched" "Detected in many" 10 "Adipocytes: 70.8;Endothelial cells: 73.9;Hepatic stellate cells: 122.0;Microglial cells: 38.4;Oligodendrocyte precursor cells: 137.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 4 "HUVEC TERT2: 90.9;NTERA-2: 45.2;TIME: 99.1" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB010359, HPA073265" Approved Supported "Plasma membrane,Centriolar satellite" "Secreted to blood" NA NA 7750000 13000000 "Cluster 9: Neutrophils - Innate immune response" "Cluster 82: Adipose tissue - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane" "Centriolar satellite" "CAB010359: AB_2203226, HPA073265: AB_2686592" "unprognostic (2.24e-1)" "unprognostic (1.74e-1)" "unprognostic (5.55e-2)" "unprognostic (1.83e-2)" "unprognostic (1.68e-1)" "unprognostic (1.26e-3)" "prognostic favorable (2.31e-5)" "unprognostic (7.48e-2)" "unprognostic (1.72e-2)" "unprognostic (1.41e-1)" "unprognostic (5.58e-2)" "unprognostic (2.72e-1)" "prognostic favorable (7.81e-4)" "unprognostic (7.50e-3)" "unprognostic (6.87e-3)" "unprognostic (1.83e-1)" "unprognostic (5.24e-3)" 20.1 9.1 8.1 5.8 7.0 0.2 14.0 6.1 8.4 9.3 4.3 5.0 3.7 12.4 2.3 5.3 6.7 11.2 16.8 7.1 6.8 23.0 10.5 28.8 3.7 7.2 6.6 3.5 3.5 4.4 3.0 46.3 7.6 3.8 5.4 0.7 3.1 6.2 10.5 2.8 5.5 12.7 6.8 28.8 4.0 1.4 9.4 1.8 9.1 22.9 2.8 6.9 3.9 6.8 0.3 0.0 3.5 0.0 0.4 5.6 0.1 3.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 6.0 2.4 0.0 1.6 0.0 0.0 1.8 0.0 2.2 0.8 0.1 90.9 0.0 0.0 0.0 0.7 0.0 0.0 0.0 45.2 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 18.3 0.0 0.0 99.1 0.0 0.5 9.1 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 8.1 7.0 6.1 8.4 7.1 6.8 7.2 6.6 7.6 6.8 9.4 6.8 70.8 3.2 1.3 1.3 0.4 1.5 0.0 0.0 0.0 0.0 0.3 0.5 8.6 0.0 0.6 1.8 0.0 0.4 0.4 0.0 0.0 0.0 0.6 0.6 0.8 73.9 0.0 2.7 4.3 0.0 2.8 4.2 0.0 0.7 0.0 0.3 122.0 1.3 0.3 0.0 5.0 0.0 0.0 6.7 2.2 0.9 0.6 0.4 0.0 38.4 0.0 0.1 0.0 137.7 2.1 1.3 0.0 0.4 0.0 0.2 0.0 0.1 0.0 0.2 0.0 1.6 1.9 0.1 0.4 0.3 1.3 1.4 0.5 1.8 0.0 0.0 TEKT3 FLJ32828 ENSG00000125409 "Tektin 3" Q9BXF9 17 15303811-15341632 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 6 "testis: 31.0" "Group enriched" "Detected in some" 10 "Early spermatids: 413.1;Late spermatids: 408.9" "Low cancer specificity" "Detected in single" "Low region specificity" "Detected in some" "Immune cell enhanced" "Detected in single" "basophil: 1.7" "Lineage enriched" "Detected in single" 5 "granulocytes: 1.7" "Cell line enhanced" "Detected in some" "HMC-1: 1.5;SuSa: 2.8" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA027293, HPA044354, HPA073565" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 11: Basophils - Unknown function" "Cluster 78: Testis - Spermatogenesis" "Cluster 12: NES - Nervous system development" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Nucleoplasm "HPA027293: , HPA044354: AB_10962623, HPA073565: " "unprognostic (1.85e-1)" "unprognostic (6.64e-3)" "unprognostic (9.73e-2)" "unprognostic (5.38e-4)" "unprognostic (4.59e-2)" "unprognostic (3.09e-2)" "unprognostic (9.07e-2)" "unprognostic (8.63e-3)" "unprognostic (4.91e-2)" "unprognostic (1.23e-1)" "unprognostic (9.67e-4)" "unprognostic (1.29e-1)" "unprognostic (1.09e-4)" "unprognostic (1.69e-2)" "unprognostic (3.00e-1)" "unprognostic (2.90e-3)" "unprognostic (7.85e-2)" 0.3 0.2 0.7 0.3 0.6 0.1 0.5 1.4 0.9 1.2 0.6 0.3 0.3 0.5 0.6 0.1 4.9 0.4 0.2 0.4 0.4 0.3 0.2 0.8 0.1 0.9 1.0 0.9 0.7 0.2 1.0 0.3 0.5 0.4 0.2 0.6 0.5 0.1 0.1 0.7 0.4 0.2 0.5 0.2 0.2 31.0 0.4 0.1 0.7 0.0 0.1 0.2 0.4 1.1 0.0 0.0 0.4 0.5 0.0 0.0 0.3 0.2 0.4 0.0 0.0 0.8 0.0 0.1 0.0 0.2 0.1 0.1 0.0 0.0 0.0 0.2 0.2 0.2 0.3 0.1 0.1 0.1 1.5 0.0 0.2 0.0 0.0 0.4 0.1 0.2 0.0 0.1 0.0 0.0 0.1 0.8 0.0 0.1 0.1 0.0 0.2 0.0 0.1 0.2 0.1 0.2 0.0 0.1 0.2 2.8 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.2 0.0 0.2 0.0 0.0 0.0 1.7 0.1 0.1 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.2 0.1 0.1 0.7 0.3 0.0 0.1 0.0 0.0 0.7 0.6 1.4 0.9 0.4 0.4 0.9 1.0 0.5 0.5 0.4 1.1 0.7 3.2 0.5 0.7 0.1 0.3 0.1 0.7 0.0 0.7 0.5 0.5 0.7 1.5 4.7 0.0 0.0 0.3 0.2 0.5 0.0 0.1 413.1 16.3 1.7 0.7 1.8 0.0 1.2 0.0 0.5 3.9 0.0 0.5 0.0 0.7 0.4 0.1 3.8 0.0 1.1 0.0 0.0 0.0 1.4 408.9 11.1 0.3 0.0 1.0 0.0 1.7 0.0 2.0 0.8 0.0 0.1 6.4 0.0 0.2 0.7 0.1 39.1 0.2 6.6 3.2 1.4 25.9 2.6 0.0 0.1 0.0 0.1 3.4 0.0 0.2 TEX9 ENSG00000151575 "Testis expressed 9" Q8N6V9 15 56244009-56445997 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 89.1;Endometrial ciliated cells: 86.2;Respiratory ciliated cells: 125.6;Spermatocytes: 74.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 12 "basophil: 4.3;memory B-cell: 14.4;naive B-cell: 11.4" "Group enriched" "Detected in many" 12 "B-cells: 14.4;granulocytes: 4.3" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA039415 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 19: B-cells - Humoral immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 49: Ciliated cells - Cilium organization" Cytosol "Plasma membrane" "HPA039415: AB_10672775" "unprognostic (3.27e-1)" "unprognostic (2.77e-2)" "unprognostic (2.25e-1)" "unprognostic (4.71e-3)" "unprognostic (2.34e-1)" "unprognostic (5.13e-2)" "unprognostic (1.54e-2)" "unprognostic (1.22e-1)" "unprognostic (3.75e-2)" "unprognostic (8.85e-2)" "unprognostic (6.91e-3)" "unprognostic (2.00e-2)" "unprognostic (1.24e-2)" "unprognostic (8.00e-2)" "unprognostic (1.15e-1)" "unprognostic (1.06e-1)" "unprognostic (1.24e-1)" 1.8 6.1 4.1 4.6 3.9 3.4 10.1 7.4 3.9 8.8 17.0 3.6 11.6 5.2 8.4 4.4 28.0 5.2 1.1 3.2 4.2 10.8 1.5 4.4 6.0 9.4 8.6 5.4 5.4 14.2 9.9 1.6 4.5 4.5 4.8 18.0 10.5 3.4 1.2 5.6 8.0 2.2 5.3 3.2 12.2 16.4 6.6 3.7 17.4 1.5 10.6 2.7 1.6 5.7 7.8 7.1 15.3 13.7 3.7 10.8 2.0 1.7 6.3 4.8 5.7 1.7 6.9 15.5 7.0 1.2 8.2 6.6 6.6 7.4 5.5 1.7 7.8 9.1 6.7 5.2 1.1 3.3 1.3 5.9 13.3 5.4 4.1 6.9 0.2 11.1 5.2 1.4 2.6 4.5 6.5 1.2 7.2 13.2 3.0 2.6 7.1 5.5 15.9 4.4 24.3 9.8 8.7 4.9 5.5 11.2 14.6 3.0 0.7 20.3 5.8 6.5 6.4 2.1 16.5 11.7 8.0 1.7 3.9 4.3 0.1 0.1 0.4 0.6 0.1 14.4 0.4 0.3 0.2 11.4 0.2 0.8 0.3 0.4 0.4 0.4 0.6 0.7 4.1 3.9 7.4 3.9 3.2 4.2 9.4 8.6 4.5 5.3 6.6 5.7 1.5 6.4 7.5 38.8 21.0 4.2 7.3 13.2 20.5 6.4 11.3 11.7 0.8 5.7 23.5 11.0 12.5 1.8 0.3 2.3 21.5 15.6 89.1 86.2 5.1 3.2 7.7 5.9 14.3 7.0 0.5 5.0 17.3 4.8 1.3 5.1 1.8 0.4 1.3 1.7 20.4 3.7 16.2 0.0 2.1 40.9 4.7 2.7 3.6 4.7 1.2 6.8 1.0 14.6 15.1 4.5 5.4 3.8 15.8 3.7 12.3 21.7 125.6 37.5 0.0 4.6 6.0 74.6 36.6 6.9 2.3 0.3 1.0 6.2 6.7 4.9 TGM1 "ICR2, LI, LI1, TGASE, TGK" ENSG00000092295 "Transglutaminase 1" P22735 14 24249114-24264432 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Plasma proteins, Potential drug targets, Predicted intracellular proteins" Keratinization "Acyltransferase, Transferase" "Disease variant, Ichthyosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "esophagus: 713.5" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 12.8;Basal respiratory cells: 63.6;Club cells: 18.8;Distal tubular cells: 29.4;Squamous epithelial cells: 34.7" "Group enriched" "Detected in many" 4 "cervical cancer: 30.8;head and neck cancer: 78.3" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "BEWO: 17.5;HaCaT: 24.2;HeLa: 16.2;MCF7: 17.5;SK-BR-3: 21.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "CAB015159, HPA040171, HPA070372" Enhanced Approved "Vesicles,Plasma membrane" NA NA 530000 "Cluster 84: Esophagus - Epithelial cell function" "Cluster 28: BEWO - Transcription regulation" "Cluster 26: Respiratory epithelial cells - Mucosal defense" "Vesicles, Plasma membrane" "CAB015159: AB_2202870, HPA040171: AB_2676869, HPA070372: " "unprognostic (2.95e-2)" "unprognostic (8.79e-2)" "unprognostic (2.92e-2)" "unprognostic (1.89e-2)" "unprognostic (2.36e-1)" "unprognostic (1.10e-1)" "unprognostic (4.04e-2)" "unprognostic (1.12e-2)" "unprognostic (2.39e-1)" "unprognostic (3.01e-2)" "unprognostic (6.72e-2)" "unprognostic (2.15e-1)" "unprognostic (1.94e-7)" "unprognostic (7.11e-2)" "unprognostic (7.38e-2)" "unprognostic (2.22e-3)" "unprognostic (1.86e-2)" 25.7 1.3 0.6 0.9 0.8 0.7 2.2 3.7 2.0 78.7 0.8 1.4 0.8 1.0 1.6 713.5 4.4 0.6 5.1 0.5 0.6 2.5 1.7 5.3 1.5 1.5 0.9 3.0 3.2 0.2 3.3 1.2 1.4 4.1 0.9 1.7 89.7 4.4 1.1 73.2 1.9 0.5 0.4 2.6 1.8 2.9 0.9 1.3 2.7 0.3 40.4 1.3 144.2 0.9 1.1 2.0 1.1 1.0 0.0 0.8 17.5 0.4 0.2 1.0 1.6 1.2 1.7 1.0 2.3 1.3 0.3 24.2 2.8 2.0 0.6 2.0 3.3 1.4 16.2 5.7 0.8 0.9 1.5 1.5 9.3 0.5 2.0 0.5 0.7 3.4 1.0 1.0 0.7 17.5 0.7 1.9 0.3 1.1 2.2 1.1 0.1 1.1 0.6 2.1 1.2 1.6 0.2 21.7 0.1 1.4 1.5 1.1 0.8 1.1 4.8 2.0 0.9 1.5 1.8 0.3 0.4 2.1 1.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.8 3.7 2.0 0.5 0.6 1.5 0.9 1.4 0.4 0.9 0.9 0.2 12.8 1.1 2.0 0.0 0.3 4.6 63.6 4.0 0.9 1.1 0.8 0.8 5.7 18.8 0.0 0.0 1.4 0.3 0.2 29.4 2.0 0.1 0.3 0.2 0.2 0.0 0.0 1.5 0.9 0.8 3.9 0.0 0.6 4.5 0.7 0.0 0.2 0.4 0.0 1.7 0.1 6.1 0.6 0.3 0.0 0.6 0.4 0.0 1.0 0.4 0.2 0.0 1.0 1.0 2.6 0.0 0.4 0.1 7.4 0.1 0.2 2.1 0.6 0.0 0.1 1.0 0.0 0.6 34.7 1.8 1.2 0.6 1.2 0.3 6.2 TGM2 TGC ENSG00000198959 "Transglutaminase 2" P21980 20 38127385-38166578 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins, Predicted secreted proteins" "Acyltransferase, Hydrolase, Protease, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "cervix: 432.0" "Cell type enhanced" "Detected in many" "Cardiomyocytes: 204.5;Cytotrophoblasts: 311.1;Ductal cells: 226.7;Endometrial stromal cells: 459.1;Hepatic stellate cells: 408.0;Hepatocytes: 205.7;Pancreatic endocrine cells: 326.5;Syncytiotrophoblasts: 374.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "CAPAN-2: 1546.7;EFO-21: 505.5;hTERT-RPE1: 994.3;HUVEC TERT2: 695.3;TIME: 924.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB002598, HPA021019, HPA029518" Enhanced Approved "Plasma membrane,Cytosol" "Secreted to extracellular matrix" Yes No 1700000 "Cluster 43: B-cells - Humoral immune response" "Cluster 46: Fibroblasts - ECM organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 36: Stromal cells - Cell proliferation" Cytosol "Plasma membrane" "CAB002598: , HPA021019: AB_1858247, HPA029518: AB_10603133" "unprognostic (7.80e-2)" "unprognostic (1.51e-1)" "unprognostic (5.22e-2)" "unprognostic (1.40e-2)" "unprognostic (1.56e-2)" "unprognostic (5.61e-3)" "unprognostic (2.81e-1)" "unprognostic (3.32e-3)" "unprognostic (3.29e-2)" "unprognostic (9.78e-3)" "prognostic unfavorable (2.97e-4)" "unprognostic (6.99e-2)" "prognostic unfavorable (1.67e-7)" "unprognostic (1.60e-2)" "unprognostic (1.93e-2)" "unprognostic (6.70e-2)" "unprognostic (6.40e-2)" 105.9 45.1 23.0 68.4 22.3 3.2 30.3 22.9 29.5 432.0 53.0 30.6 29.8 266.3 28.3 37.3 217.7 127.7 394.9 21.4 23.0 76.7 244.1 288.5 18.0 25.4 22.5 40.6 25.6 19.3 95.9 234.3 26.0 88.7 20.8 2.1 9.8 56.6 63.9 4.0 63.7 159.0 24.4 32.7 62.3 3.9 30.6 15.4 36.3 33.4 10.3 154.2 87.8 24.8 65.0 47.5 0.2 1.8 47.3 5.1 24.0 95.5 45.2 0.7 1.8 78.4 1546.7 0.1 505.5 1.0 105.4 1.7 0.1 221.7 3.4 0.7 0.2 10.3 2.6 35.0 191.9 0.0 0.5 5.2 0.4 40.2 0.3 994.3 695.3 0.0 21.4 0.1 16.0 0.3 0.0 0.6 0.8 0.9 4.6 0.0 0.1 0.3 69.0 0.0 0.0 1.3 224.4 0.2 7.6 31.6 2.2 0.6 924.2 1.6 57.6 7.8 46.3 0.0 0.6 0.8 60.7 0.1 18.4 0.0 0.0 0.0 0.0 0.6 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 23.0 22.3 22.9 29.5 21.4 23.0 25.4 22.5 26.0 24.4 30.6 24.8 58.0 9.6 18.3 0.0 7.4 0.5 10.4 41.0 0.6 0.0 8.5 8.8 204.5 31.5 55.3 14.7 2.1 311.1 0.1 11.7 3.9 226.7 3.2 16.7 459.1 183.8 0.0 74.5 0.1 145.7 38.6 37.7 0.5 13.1 2.5 2.8 408.0 205.7 54.4 0.0 0.1 1.8 6.1 23.7 2.1 5.0 1.2 35.5 0.0 28.1 6.5 0.4 0.0 0.0 0.3 326.5 1.1 6.0 0.0 68.6 63.0 27.6 23.6 0.5 0.0 5.2 49.1 0.4 4.0 0.9 0.0 374.2 3.9 2.1 3.3 26.4 THY1 CD90 ENSG00000154096 "Thy-1 cell surface antigen" P04216 11 119415476-119424985 "CD markers, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 286.8;smooth muscle: 304.7;urinary bladder: 216.7" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 141.6;Excitatory neurons: 116.0;Fibroblasts: 201.9;Inhibitory neurons: 104.1;Muller glia cells: 108.1;Proximal tubular cells: 199.9;Smooth muscle cells: 226.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "ASC diff: 461.3;BJ: 738.4;BJ hTERT+: 832.5;fHDF/TERT166: 1330.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003733, CAB068243, CAB068244" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 14000000 "Cluster 16: MAIT-cells - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 50: Fibroblasts - ECM organization" Nucleoplasm "Plasma membrane" "CAB068243: AB_2665687, CAB068244: AB_2665688, HPA003733: AB_1846340" "unprognostic (9.98e-2)" "unprognostic (2.71e-1)" "unprognostic (5.13e-2)" "unprognostic (2.61e-1)" "prognostic unfavorable (6.87e-4)" "unprognostic (7.43e-2)" "unprognostic (1.43e-3)" "unprognostic (2.38e-2)" "unprognostic (1.29e-1)" "unprognostic (2.90e-3)" "unprognostic (3.38e-2)" "unprognostic (3.52e-1)" "prognostic unfavorable (2.40e-6)" "unprognostic (1.75e-2)" "unprognostic (1.90e-2)" "unprognostic (3.03e-2)" "unprognostic (1.14e-2)" 90.6 16.4 97.9 78.6 114.8 0.2 25.6 12.9 286.8 78.9 0.0 35.4 10.2 58.6 27.8 29.4 23.1 101.0 12.9 135.4 73.3 142.2 7.4 21.6 40.4 83.6 37.0 9.2 14.8 39.4 18.1 62.0 60.8 15.5 41.8 25.3 8.5 47.0 3.4 13.9 14.5 304.7 35.4 21.9 17.4 11.4 43.6 73.2 37.9 8.3 35.6 216.7 21.7 108.7 0.7 3.9 108.5 0.1 461.3 331.5 0.3 738.4 832.5 263.6 289.3 0.2 0.2 0.4 0.1 1330.6 121.9 0.9 4.3 1.1 200.7 65.1 0.0 41.5 14.4 0.0 142.7 0.0 0.2 247.5 0.0 335.6 11.6 355.2 0.3 22.6 0.0 0.6 206.5 0.1 0.6 0.1 173.9 0.0 1.4 0.5 50.7 0.3 0.1 0.2 18.1 47.9 0.1 0.4 0.2 32.9 1.0 2.1 0.0 368.6 120.9 107.3 110.1 0.3 19.7 0.4 1.1 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 97.9 114.8 12.9 286.8 135.4 73.3 83.6 37.0 60.8 35.4 43.6 108.7 68.2 0.0 1.8 17.3 2.1 17.7 0.3 1.7 0.0 27.2 1.6 40.0 0.9 0.0 0.0 9.2 0.0 1.9 0.2 0.0 21.5 0.9 1.0 5.1 141.6 69.2 0.0 0.0 116.0 0.0 2.6 201.9 1.5 3.2 1.3 0.0 17.5 0.1 4.0 32.0 104.1 0.0 0.0 0.0 25.0 2.7 96.3 2.7 17.8 21.5 0.0 108.1 0.0 64.3 22.7 0.4 0.0 77.5 0.1 0.3 0.0 199.9 0.0 27.5 32.9 9.3 226.6 0.3 0.6 0.2 17.6 4.0 4.5 6.2 0.0 0.6 TIGD7 Sancho ENSG00000140993 "Tigger transposable element derived 7" Q6NT04 16 3298808-3305729 "Predicted intracellular proteins" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 20.6" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA041357, HPA041474" Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 24: NB-4 - Immune response" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA041357: AB_10794992, HPA041474: AB_10795696" "unprognostic (7.69e-2)" "unprognostic (3.04e-4)" "unprognostic (6.56e-3)" "unprognostic (1.18e-3)" "unprognostic (1.79e-1)" "unprognostic (4.04e-2)" "unprognostic (6.50e-3)" "unprognostic (2.44e-1)" "unprognostic (2.78e-2)" "unprognostic (9.81e-2)" "unprognostic (8.56e-3)" "unprognostic (2.09e-1)" "unprognostic (2.25e-2)" "unprognostic (8.87e-2)" "unprognostic (4.04e-1)" "unprognostic (5.90e-3)" "unprognostic (3.12e-2)" 2.9 3.3 5.1 1.8 5.1 0.6 4.7 6.0 6.1 5.1 7.0 4.9 1.8 5.5 4.5 1.9 5.1 2.6 5.3 4.9 5.6 6.0 3.1 2.8 3.4 5.2 5.6 10.6 2.8 6.5 8.2 3.2 5.5 5.6 1.9 5.1 2.7 5.0 4.2 2.1 2.8 3.5 5.0 4.8 2.7 8.5 5.2 3.7 6.7 5.3 3.0 4.1 3.4 5.7 0.9 1.9 5.5 3.0 2.4 3.6 4.2 2.7 1.6 4.0 3.7 0.2 1.7 2.0 4.5 2.0 3.3 0.5 1.8 0.7 5.0 0.2 2.7 5.9 1.7 0.1 2.8 1.0 7.5 3.9 1.3 3.7 1.1 4.7 3.1 1.4 2.9 3.5 3.4 1.2 1.9 9.0 6.3 0.6 5.1 10.2 1.3 8.3 2.2 0.5 7.1 2.6 6.8 0.9 2.7 4.8 3.2 3.3 1.2 2.6 6.2 2.7 1.6 7.5 8.3 6.5 1.5 3.4 2.9 0.5 0.6 3.4 1.5 0.5 2.7 0.6 1.2 2.3 0.5 2.5 2.4 1.7 2.1 2.0 1.7 0.5 1.4 0.7 5.1 5.1 6.0 6.1 4.9 5.6 5.2 5.6 5.5 5.0 5.2 5.7 1.7 9.6 4.5 11.4 4.9 0.8 3.2 2.1 4.0 6.1 2.4 2.4 9.9 4.3 4.4 0.0 4.2 1.5 1.6 0.6 3.9 2.8 4.7 2.3 3.8 2.3 1.2 2.5 14.6 1.4 1.1 2.6 4.6 1.7 1.3 5.9 0.4 0.6 0.9 5.0 12.7 1.0 4.1 0.6 0.8 2.0 2.8 1.1 5.4 2.8 0.9 3.4 4.1 20.6 12.1 1.1 0.1 4.5 2.0 2.3 1.0 0.9 2.9 2.2 6.6 3.1 3.6 11.6 10.5 2.1 0.6 1.4 2.9 3.8 0.6 1.5 TLR4 "ARMD10, CD284, hToll, TLR-4" ENSG00000136869 "Toll like receptor 4" O00206 9 117704175-117724735 "CD markers, Enzymes, FDA approved drug targets, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Immunity, Inflammatory response, Innate immunity" "Hydrolase, Receptor" "Age-related macular degeneration, FDA approved drug targets" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 38.6;Astrocytes: 50.9;Hepatic stellate cells: 62.8;Hofbauer cells: 38.2;Kupffer cells: 106.0;Macrophages: 64.5;monocytes: 54.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "neutrophil: 86.8" "Group enriched" "Detected in many" 33 "dendritic cells: 22.4;granulocytes: 86.8;monocytes: 65.6" "Cell line enhanced" "Detected in many" "Karpas-707: 60.0;TIME: 43.5" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "CAB004025, HPA049174" Approved Supported "Golgi apparatus,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 14: Monocytes - Unknown function" "Cluster 40: Neutrophils - Inflammatory response" "Cluster 2: Karpas-707 - Immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" "Golgi apparatus" "CAB004025: , HPA049174: AB_2680662" "unprognostic (1.60e-1)" "unprognostic (8.34e-2)" "unprognostic (7.22e-2)" "prognostic favorable (6.29e-4)" "unprognostic (3.39e-1)" "unprognostic (7.48e-2)" "unprognostic (8.68e-2)" "unprognostic (1.80e-1)" "unprognostic (3.38e-1)" "unprognostic (5.18e-2)" "unprognostic (8.00e-2)" "unprognostic (9.42e-2)" "unprognostic (4.08e-2)" "unprognostic (8.63e-2)" "prognostic unfavorable (3.79e-4)" "unprognostic (1.09e-2)" "unprognostic (1.96e-2)" 31.1 11.0 12.4 25.7 15.7 22.3 12.0 11.7 8.3 6.5 1.7 6.7 4.3 5.6 1.2 4.8 4.8 10.8 8.4 10.3 17.8 6.8 16.7 16.2 13.1 12.3 14.0 6.0 2.6 2.5 2.1 23.9 12.4 4.6 7.3 2.9 6.0 3.2 3.1 3.5 5.8 10.8 14.9 32.6 4.4 1.5 14.2 3.5 5.5 12.0 7.7 13.3 2.7 10.1 0.0 0.0 25.5 0.0 11.1 23.0 0.1 10.2 17.9 2.5 1.5 0.0 2.6 3.6 0.5 26.7 7.5 0.1 0.0 2.2 3.7 0.0 0.0 5.7 5.1 0.4 8.1 19.1 0.1 14.2 0.0 5.4 0.7 22.5 31.4 0.0 0.0 60.0 29.2 0.0 0.0 2.9 3.1 2.4 1.2 0.0 28.0 19.8 0.9 28.9 0.0 0.1 6.4 0.0 1.0 2.2 0.0 10.4 43.5 1.4 18.4 0.1 4.8 0.0 0.0 0.0 0.9 19.1 15.2 64.0 64.9 21.5 0.1 57.5 0.0 1.7 0.1 0.0 22.4 0.5 0.0 0.0 86.8 0.1 65.6 0.9 0.0 25.5 12.4 15.7 11.7 8.3 10.3 17.8 12.3 14.0 12.4 14.9 14.2 10.1 38.6 0.0 5.0 50.9 2.3 0.8 0.3 0.1 0.6 0.2 3.5 1.0 2.9 2.8 2.9 0.0 0.0 0.3 0.1 1.6 0.0 0.1 0.1 3.5 29.2 31.6 0.0 1.3 0.2 0.2 0.2 11.5 1.5 6.8 15.8 1.2 62.8 1.9 38.2 0.0 0.2 2.0 0.0 106.0 8.6 0.4 0.0 64.5 1.8 26.2 54.0 8.8 2.1 7.5 0.3 0.5 6.1 0.0 0.1 0.1 0.0 0.4 3.7 1.3 6.6 5.5 4.5 0.1 0.3 0.3 0.0 0.8 0.9 3.1 1.2 3.3 TM4SF20 "FLJ22800, TCCE518" ENSG00000168955 "Transmembrane 4 L six family member 20" Q53R12 2 227362038-227381995 "Disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Autism spectrum disorder" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 76 "intestine: 266.6" "Cell type enriched" "Detected in some" 4 "Proximal enterocytes: 703.0" "Group enriched" "Detected in many" 6 "colorectal cancer: 5.0;liver cancer: 4.7;pancreatic cancer: 5.5;stomach cancer: 11.8" "Region enhanced" "Detected in single" "cerebellum: 1.2" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 2.6;RPMI-8226: 1.7" "Not detected" "Not detected" "Low region specificity" "Detected in all" "HPA051838, HPA063184, HPA065531" Uncertain Supported "Plasma membrane,Focal adhesion sites" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 56: Intestine - Transmembrane transport" "Cluster 25: RPMI-8226 - Immune response" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Focal adhesion sites" "HPA051838: AB_2681631, HPA063184: AB_2684958, HPA065531: AB_2685506" "unprognostic (4.68e-2)" "unprognostic (1.13e-1)" "unprognostic (8.75e-2)" "unprognostic (4.96e-2)" "unprognostic (2.84e-2)" "unprognostic (1.63e-1)" "unprognostic (2.51e-1)" "unprognostic (2.36e-1)" "unprognostic (2.95e-1)" "unprognostic (1.20e-2)" "unprognostic (1.19e-1)" "unprognostic (3.44e-3)" "unprognostic (7.76e-2)" "unprognostic (2.60e-2)" "unprognostic (3.04e-3)" 0.1 0.1 0.2 0.3 0.2 0.2 0.0 1.2 0.4 0.0 0.4 3.1 266.6 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 3.9 0.3 0.0 0.0 0.0 0.3 144.5 1.6 0.0 0.1 0.5 3.5 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.7 0.0 2.6 0.0 0.0 0.0 0.0 0.4 0.3 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.5 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.2 0.1 0.0 0.0 0.6 0.1 0.0 0.0 0.1 0.0 1.7 0.0 0.1 0.2 0.6 0.4 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.7 0.0 0.1 0.1 0.1 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.1 0.0 0.1 0.0 0.0 0.2 0.2 1.2 0.4 0.1 0.0 0.1 0.0 0.1 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 15.1 0.0 0.0 48.4 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 21.4 0.0 0.0 0.0 77.3 0.0 0.1 0.0 0.0 0.0 0.2 0.0 1.0 0.5 0.0 157.9 0.7 0.0 0.0 703.0 0.0 0.0 0.3 0.0 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.0 18.8 0.0 TM4SF4 il-TMP ENSG00000169903 "Transmembrane 4 L six family member 4" P48230 3 149474697-149503394 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 11 "gallbladder: 945.8;intestine: 650.8;liver: 703.8" "Group enriched" "Detected in some" 17 "Cholangiocytes: 2070.3;Hepatocytes: 578.1" "Group enriched" "Detected in many" 10 "liver cancer: 249.4;pancreatic cancer: 130.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 6 "A549: 22.7;OE19: 20.3;RPTEC TERT1: 36.5" "Not detected" "Not detected" "Low region specificity" "Detected in all" HPA046430 Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 2: Hepatocytes - Metabolism" "Plasma membrane" Cytosol "HPA046430: AB_2679662" "unprognostic (1.91e-2)" "unprognostic (1.71e-1)" "unprognostic (2.15e-1)" "unprognostic (1.66e-1)" "unprognostic (2.27e-1)" "unprognostic (1.67e-1)" "unprognostic (1.33e-1)" "unprognostic (4.96e-2)" "unprognostic (2.73e-1)" "unprognostic (1.98e-1)" "unprognostic (7.60e-2)" "unprognostic (1.83e-1)" "unprognostic (4.66e-2)" "unprognostic (1.91e-2)" "unprognostic (4.97e-1)" 0.3 1.2 0.0 0.8 0.0 0.0 0.1 0.0 0.0 0.1 0.0 2.0 650.8 0.6 2.3 0.7 0.5 945.8 0.3 0.0 0.0 0.8 703.8 0.3 0.8 0.0 0.0 0.0 72.5 0.0 0.1 0.0 0.0 0.1 1.2 0.0 0.0 0.0 0.0 0.0 514.8 0.9 0.0 0.1 21.3 0.6 0.0 0.0 0.4 0.0 0.0 0.2 0.0 0.0 0.0 22.7 0.0 0.0 0.0 0.0 1.5 1.1 0.0 0.0 0.0 0.6 0.3 0.2 4.1 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 0.7 0.0 0.1 0.8 0.1 20.3 0.0 0.0 0.5 1.4 36.5 0.0 0.6 1.2 1.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 2.5 0.0 0.1 0.1 0.5 1.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 3.2 0.5 0.0 1.0 0.1 0.1 0.0 0.0 0.0 0.2 0.1 4.1 2070.3 0.6 0.0 0.0 0.0 0.0 0.8 0.0 25.9 1.1 3.1 0.3 0.6 3.0 13.5 0.1 2.0 0.2 0.1 10.7 3.3 0.0 0.0 7.1 578.1 0.1 0.0 0.1 41.6 0.0 11.6 0.0 0.5 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.1 8.2 17.5 0.0 0.3 0.0 76.6 4.8 0.1 0.0 0.0 0.0 0.7 4.1 0.3 0.0 0.0 0.1 0.5 5.6 2.0 0.2 TMC5 FLJ13593 ENSG00000103534 "Transmembrane channel like 5" Q6UXY8 16 19410496-19499113 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 53.4;stomach 1: 46.0" "Cell type enhanced" "Detected in many" "Club cells: 282.4;Pancreatic endocrine cells: 302.2;Proximal enterocytes: 374.3;Respiratory ciliated cells: 624.7" "Low cancer specificity" "Detected in many" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "CAPAN-2: 69.7;OE19: 41.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA040810, HPA042037" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 9: Intestine - Unknown function" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA040810: AB_10795627, HPA042037: AB_10804126" "unprognostic (2.47e-2)" "unprognostic (3.68e-1)" "unprognostic (3.50e-2)" "unprognostic (2.74e-3)" "unprognostic (1.01e-1)" "unprognostic (3.64e-2)" "prognostic unfavorable (7.96e-4)" "unprognostic (1.21e-1)" "unprognostic (1.59e-1)" "unprognostic (9.74e-2)" "unprognostic (3.27e-2)" "unprognostic (3.71e-1)" "unprognostic (2.28e-2)" "unprognostic (2.69e-1)" "unprognostic (7.88e-2)" "unprognostic (8.88e-3)" "unprognostic (1.75e-1)" 0.6 0.1 0.2 3.1 0.4 1.5 12.7 0.5 0.3 8.9 5.6 21.6 45.4 2.1 17.5 1.2 5.1 25.5 0.1 0.3 0.0 0.3 0.6 18.9 0.2 0.2 0.2 0.1 2.3 6.0 0.1 3.2 0.2 12.2 22.7 0.2 22.8 0.2 0.1 1.8 53.4 1.1 0.0 0.1 46.0 3.8 0.2 0.1 0.7 0.0 1.1 3.2 0.5 0.2 6.9 10.8 0.0 0.3 0.0 0.0 9.7 0.1 0.0 0.0 0.0 0.1 69.7 0.0 0.3 0.0 0.2 4.4 1.1 0.0 0.0 0.1 0.1 0.0 1.8 0.1 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.3 0.1 0.0 1.1 0.0 0.2 2.5 41.5 3.1 0.0 0.0 2.6 0.1 0.3 0.7 0.2 0.1 2.1 0.0 1.1 0.9 0.0 0.0 0.0 0.3 0.2 0.1 0.1 0.1 0.1 0.2 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.2 0.4 0.5 0.3 0.3 0.0 0.2 0.2 0.2 0.0 0.2 0.2 0.1 157.0 162.5 0.0 1.8 0.8 22.9 46.6 2.8 0.3 57.4 17.9 0.9 102.9 282.4 22.0 2.1 39.0 1.0 173.7 0.0 121.1 32.8 107.0 6.9 2.9 38.9 8.0 1.9 166.3 3.4 3.3 188.1 88.4 5.7 11.0 0.7 0.6 2.7 3.3 2.0 101.5 26.4 0.0 1.1 32.6 0.3 1.8 1.8 0.0 1.0 0.2 0.0 0.5 0.9 302.2 180.9 0.7 0.5 103.1 374.3 2.0 624.7 1.9 0.0 0.4 9.5 1.3 1.1 2.2 1.7 16.3 1.3 1.5 125.1 55.9 TMCO5A "MGC35118, TMCO5" ENSG00000166069 "Transmembrane and coiled-coil domains 5A" Q8N6Q1 15 37921939-37967724 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in single" 141 "testis: 90.7" "Group enriched" "Detected in some" 104 "Early spermatids: 1153.9;Late spermatids: 3910.6" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Not detected" "Not detected" "HPA056530, HPA064017" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 74: Testis - Spermatogenesis" "Cluster 31: Spermatids - Spermatogenesis" "Plasma membrane, Cytosol" "HPA056530: AB_2683167, HPA064017: " "unprognostic (2.60e-1)" "unprognostic (1.69e-4)" 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.2 0.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 90.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.1 0.1 0.0 0.0 0.2 0.1 0.2 0.0 0.1 0.1 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.7 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1153.9 0.2 0.0 0.8 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 3910.6 13.4 1.1 0.0 0.0 0.0 0.0 0.0 1.0 1.4 0.0 0.0 10.9 0.0 0.0 0.0 0.0 1.1 0.0 6.6 0.0 0.0 24.2 8.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 TMED8 FAM15B ENSG00000100580 "Transmembrane p24 trafficking protein family member 8" Q6PL24 14 77335029-77377094 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 62.7;Cone photoreceptor cells: 108.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Daudi: 58.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001205 Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 20: Retina & Lymphoid tissues - Unknown function" "Cluster 3: HMC-1 - Innate immune response" "Cluster 57: B-cells - Immune response" "Plasma membrane" Vesicles "HPA001205: AB_2204460" "unprognostic (1.07e-1)" "unprognostic (4.70e-2)" "unprognostic (4.85e-2)" "unprognostic (2.39e-1)" "unprognostic (1.13e-1)" "unprognostic (7.82e-2)" "unprognostic (1.68e-2)" "unprognostic (3.74e-2)" "unprognostic (1.22e-1)" "unprognostic (2.01e-1)" "unprognostic (2.81e-2)" "unprognostic (1.04e-1)" "unprognostic (1.03e-3)" "unprognostic (2.23e-3)" "unprognostic (1.12e-1)" "unprognostic (5.88e-2)" "unprognostic (2.77e-1)" 5.5 8.3 8.2 8.6 9.6 7.7 5.7 4.7 8.4 5.9 4.1 4.4 3.3 6.7 5.1 3.6 5.4 4.1 3.4 7.5 16.6 10.4 3.4 4.6 17.5 7.9 10.5 7.3 5.6 11.1 9.2 4.4 11.2 5.9 4.8 24.2 4.4 5.9 2.3 4.9 5.5 5.6 6.9 8.0 6.2 6.8 12.8 9.8 10.9 2.4 19.5 4.7 3.5 5.9 14.7 12.0 13.9 12.4 8.5 7.6 11.8 9.2 6.0 9.4 10.1 7.5 8.1 58.7 7.5 7.5 7.7 10.0 10.4 10.5 14.6 18.6 6.3 19.6 9.5 7.9 5.9 9.6 51.8 8.0 7.4 12.3 11.0 9.5 13.5 47.7 10.1 15.4 9.5 14.4 15.2 14.2 6.9 10.7 12.0 12.2 12.7 4.7 9.9 9.0 17.2 10.4 15.9 9.4 11.8 10.6 15.2 15.9 9.7 9.7 6.2 17.5 10.7 12.3 25.2 28.9 11.1 17.7 14.3 2.3 0.7 2.2 0.3 0.9 0.4 2.1 0.5 0.4 0.6 2.1 0.3 0.5 1.0 0.5 0.8 1.0 0.7 0.5 8.2 9.6 4.7 8.4 7.5 16.6 7.9 10.5 11.2 6.9 12.8 5.9 6.6 3.2 7.8 62.7 33.9 6.6 4.9 7.7 2.8 33.4 12.5 8.3 16.8 8.6 5.3 22.0 108.4 10.5 7.9 6.5 5.9 6.4 4.8 9.8 15.5 10.4 44.3 15.4 44.7 4.7 10.0 8.4 7.1 9.0 0.0 9.1 8.9 9.8 7.8 28.6 40.7 6.3 10.2 24.8 7.7 6.9 14.6 19.8 5.4 21.5 16.8 14.9 6.2 39.7 24.2 6.8 3.3 14.3 19.9 7.5 3.2 22.2 20.9 39.3 13.1 7.1 8.4 6.8 15.7 8.2 8.9 4.1 10.3 19.8 6.7 4.3 TMEM101 "FLJ23987, MGC4251" ENSG00000091947 "Transmembrane protein 101" Q96IK0 17 44011188-44023946 "Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Endometrial ciliated cells: 237.2;Glandular and luminal cells: 507.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA039739, HPA075651" Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 1: Thyroid gland - Transcription" "Cluster 37: Hep G2 - Hepatocyte cell processes" "Cluster 44: Endometrium - Transcription" "Nucleoplasm, Plasma membrane" "HPA039739: AB_2676657, HPA075651: " "unprognostic (1.40e-3)" "unprognostic (1.75e-1)" "unprognostic (1.67e-1)" "prognostic favorable (4.29e-4)" "unprognostic (5.91e-2)" "unprognostic (3.91e-3)" "prognostic unfavorable (7.10e-4)" "unprognostic (1.80e-2)" "unprognostic (2.43e-1)" "unprognostic (2.03e-1)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "prognostic favorable (4.10e-5)" "unprognostic (1.59e-2)" "unprognostic (2.02e-1)" "unprognostic (1.48e-1)" "unprognostic (2.32e-2)" 17.2 19.8 22.6 12.9 26.8 11.5 107.0 23.2 24.0 44.4 24.2 20.6 16.9 63.5 27.6 28.0 37.9 15.9 23.1 22.2 22.7 93.9 24.1 18.7 19.4 24.2 24.0 22.7 39.2 26.4 15.4 21.6 23.2 24.0 16.9 12.1 30.1 111.8 33.3 29.0 17.4 16.1 23.5 20.4 28.8 23.6 23.9 16.5 23.0 24.9 17.7 20.4 23.0 23.4 23.5 56.0 19.7 16.2 45.7 43.9 19.6 24.1 36.1 46.5 43.8 42.0 59.5 26.1 6.5 24.9 36.0 35.3 22.9 41.5 35.2 28.5 46.1 19.5 45.7 86.2 39.3 31.7 32.8 39.4 46.5 32.8 46.3 41.8 40.8 45.0 40.7 50.1 29.2 31.7 34.6 36.6 9.1 25.4 62.6 29.8 42.8 47.4 39.1 18.7 25.3 20.2 14.6 0.5 59.6 24.9 27.3 59.9 24.7 42.1 28.5 18.8 46.9 52.1 38.0 12.0 44.3 29.7 38.2 20.1 42.8 15.3 31.2 43.4 35.7 37.3 39.6 36.4 44.9 39.8 43.2 35.7 15.9 44.1 32.9 44.0 44.6 31.1 22.6 26.8 23.2 24.0 22.2 22.7 24.2 24.0 23.2 23.5 23.9 23.4 22.1 19.2 15.4 0.0 22.8 20.6 31.6 72.0 21.6 10.4 64.2 61.2 27.3 24.3 34.5 40.5 6.2 68.5 19.6 18.5 37.2 36.6 13.1 237.2 70.8 28.2 23.4 33.2 0.0 49.8 47.3 21.1 13.7 507.4 22.9 34.4 36.0 20.6 37.6 11.8 0.0 37.3 28.5 32.4 11.8 11.1 13.1 23.8 33.8 0.0 47.7 17.7 29.9 0.0 0.0 41.8 20.7 12.4 29.4 23.4 27.7 30.2 27.1 11.7 6.6 13.2 19.8 45.8 24.7 26.9 22.6 44.6 20.9 25.6 45.7 25.2 TMEM139 FLJ90586 ENSG00000178826 "Transmembrane protein 139" Q8IV31 7 143279957-143288048 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 33.8;kidney: 32.2" "Cell type enhanced" "Detected in many" "Collecting duct cells: 51.5;Ductal cells: 49.0;Proximal enterocytes: 90.7;Proximal tubular cells: 89.1" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A-431: 22.4;CAPAN-2: 40.8;EFO-21: 27.9;RPTEC TERT1: 70.5;SK-BR-3: 25.0;T-47d: 68.5" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA036982, HPA036983" Approved Approved "Plasma membrane,Focal adhesion sites" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 35: RPTEC-TERT1 - Kidney processes" "Cluster 67: Proximal tubular cells - Tubular reabsorption" "Plasma membrane" "Focal adhesion sites" "HPA036982: AB_2675413, HPA036983: AB_10672275" "unprognostic (2.58e-1)" "unprognostic (4.38e-1)" "unprognostic (6.62e-3)" "unprognostic (1.41e-1)" "unprognostic (2.10e-1)" "unprognostic (2.16e-3)" "unprognostic (2.83e-2)" "unprognostic (4.90e-2)" "unprognostic (1.60e-1)" "unprognostic (2.82e-2)" "prognostic unfavorable (1.66e-4)" "unprognostic (2.89e-1)" "prognostic favorable (3.05e-5)" "unprognostic (1.73e-1)" "unprognostic (1.42e-2)" "unprognostic (2.83e-2)" "unprognostic (9.08e-3)" 1.1 2.7 1.9 2.2 6.4 0.0 3.2 6.6 3.2 8.9 2.9 5.7 33.8 1.2 1.3 0.4 6.8 7.2 3.3 1.6 4.1 32.2 9.2 5.1 0.2 10.5 6.9 0.4 8.7 6.8 1.8 5.2 8.9 0.9 4.5 0.8 4.8 3.1 0.1 1.2 19.3 0.4 5.9 0.9 2.5 3.8 5.7 0.0 7.2 0.0 0.1 1.8 0.3 13.9 22.4 1.6 0.3 0.1 0.0 0.0 14.3 0.2 0.0 0.0 0.0 5.2 40.8 0.3 27.9 0.0 1.8 18.5 0.0 9.3 0.0 0.3 0.0 0.0 2.4 3.1 0.0 0.2 0.1 0.0 0.0 0.0 0.2 0.9 0.0 1.3 0.0 0.5 0.0 1.5 1.6 1.0 0.0 0.5 1.6 0.4 0.3 0.0 70.5 5.6 0.4 0.1 1.1 25.0 0.2 0.5 68.5 0.0 0.0 0.3 0.7 0.0 0.1 0.0 0.1 0.3 0.3 0.3 0.3 0.0 0.0 0.2 0.0 0.8 0.0 0.1 0.3 0.2 0.0 0.0 0.3 0.1 0.0 0.0 0.8 0.0 0.6 0.1 1.9 6.4 6.6 3.2 1.6 4.1 10.5 6.9 8.9 5.9 5.7 13.9 0.6 16.0 5.9 0.7 0.2 0.1 2.1 2.8 0.0 0.2 8.2 15.5 2.3 27.1 5.4 51.5 0.0 30.5 0.2 28.9 35.2 49.0 14.8 16.2 1.6 0.7 3.6 0.0 0.0 4.7 5.2 0.4 3.1 17.9 0.0 2.2 1.4 16.2 1.9 0.0 0.2 6.7 0.0 0.6 0.3 13.6 0.0 0.7 5.4 0.0 1.1 7.7 0.0 0.0 5.2 30.6 23.3 0.0 0.0 1.2 90.7 89.1 3.8 0.1 0.0 0.0 0.9 0.1 0.2 0.6 0.0 6.4 0.8 0.7 12.9 1.4 TMEM218 ENSG00000150433 "Transmembrane protein 218" A2RU14 11 125096545-125111763 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038489 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 72: Non-specific - Transcription" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 4: Macrophages - Innate immune response" "Plasma membrane, Cytosol" "HPA038489: AB_10672748" "unprognostic (3.70e-2)" "unprognostic (1.16e-1)" "unprognostic (7.60e-2)" "unprognostic (2.41e-3)" "unprognostic (8.86e-2)" "unprognostic (1.60e-1)" "prognostic unfavorable (1.93e-5)" "unprognostic (3.63e-2)" "unprognostic (7.09e-3)" "unprognostic (2.18e-1)" "unprognostic (6.45e-2)" "unprognostic (1.09e-1)" "unprognostic (9.95e-2)" "prognostic favorable (5.50e-4)" "unprognostic (6.53e-2)" "unprognostic (1.42e-1)" "unprognostic (6.72e-2)" 17.7 18.1 4.8 9.5 5.5 5.3 14.0 5.3 6.5 15.5 5.3 13.5 8.4 16.6 6.9 11.6 14.8 7.4 10.2 4.6 5.4 12.7 12.9 12.0 10.5 6.0 5.5 15.0 14.5 10.3 15.2 5.9 5.8 13.0 6.0 6.5 10.9 6.8 9.2 8.9 11.8 8.3 5.7 16.6 13.2 5.6 5.1 8.4 10.9 5.7 7.0 13.8 13.2 6.3 12.5 24.0 14.9 18.2 13.5 18.6 9.0 12.2 9.2 9.3 12.0 2.5 35.9 15.6 29.9 7.5 14.2 14.2 9.4 11.6 12.2 22.0 13.5 35.1 6.1 10.0 13.3 11.1 12.6 14.7 15.2 16.5 19.6 14.9 13.7 19.1 14.4 19.4 16.2 6.4 2.9 23.3 12.2 34.0 22.6 16.3 18.0 12.0 8.3 12.3 12.9 19.4 16.6 6.6 9.1 8.7 31.3 15.7 17.6 11.4 10.3 13.4 13.5 11.1 10.1 12.9 9.1 22.9 20.3 43.7 40.1 17.4 21.6 31.6 18.7 29.6 20.5 20.5 47.4 23.9 17.2 20.4 15.7 32.5 30.9 41.1 20.5 27.0 4.8 5.5 5.3 6.5 4.6 5.4 6.0 5.5 5.8 5.7 5.1 6.3 21.0 19.2 13.4 7.8 17.8 12.1 19.6 34.6 19.4 7.0 22.1 24.6 8.1 15.7 16.6 14.7 0.0 28.0 18.1 5.7 27.4 20.5 3.4 23.1 22.4 15.8 10.8 14.5 4.4 16.2 18.4 21.1 8.6 10.6 3.8 22.2 18.5 15.1 42.2 23.5 7.4 11.7 20.3 21.0 17.5 1.9 10.2 21.9 17.8 14.0 26.0 26.0 18.6 9.5 11.2 13.1 3.9 16.6 15.8 9.4 8.5 19.7 29.4 12.4 26.3 16.7 18.3 16.6 13.8 18.0 14.2 9.7 14.5 27.0 13.7 16.6 TMEM245 "C9orf5, CG-2" ENSG00000106771 "Transmembrane protein 245" Q9H330 9 109015135-109119947 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023892 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 48: Parathyroid gland - membrane proteins" "Cluster 39: CACO-2 - Unknown function" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA023892: AB_1845828" "unprognostic (1.56e-2)" "unprognostic (1.65e-1)" "unprognostic (1.29e-1)" "unprognostic (9.58e-2)" "unprognostic (1.63e-1)" "unprognostic (6.43e-2)" "unprognostic (1.66e-1)" "unprognostic (5.96e-2)" "unprognostic (1.18e-1)" "unprognostic (1.03e-1)" "unprognostic (2.05e-1)" "unprognostic (1.85e-1)" "prognostic favorable (4.46e-9)" "unprognostic (6.11e-2)" "unprognostic (2.44e-1)" "unprognostic (2.41e-1)" "unprognostic (2.24e-2)" 29.2 47.6 18.1 12.4 19.4 7.3 20.2 16.8 19.4 21.0 32.6 22.9 12.6 27.3 26.1 23.1 29.2 19.2 43.1 19.6 21.4 45.9 25.2 28.7 15.1 17.3 19.6 45.3 24.6 65.1 11.3 29.1 17.8 25.5 16.9 27.7 26.2 33.9 35.4 14.2 15.9 34.2 20.6 17.9 17.8 16.8 22.0 17.0 74.2 39.2 11.6 18.9 11.9 18.4 32.3 42.2 30.5 10.3 69.9 39.9 67.0 45.4 35.0 47.9 37.6 56.9 62.9 28.9 45.3 34.7 46.4 49.5 39.1 29.2 56.2 37.8 16.8 36.0 32.2 33.7 30.5 27.5 27.2 42.9 29.2 46.7 42.8 51.5 40.7 31.5 24.4 31.2 55.1 21.2 36.8 12.6 33.9 43.2 37.5 20.8 60.3 18.0 50.8 31.0 16.8 16.4 30.0 29.6 30.2 44.9 39.6 15.4 44.9 37.0 27.7 34.9 52.4 20.6 56.9 9.2 51.5 14.5 54.9 4.4 1.6 1.5 2.4 1.1 2.9 1.5 4.0 3.4 1.6 2.1 5.2 3.6 0.6 3.3 2.4 2.2 4.3 1.8 18.1 19.4 16.8 19.4 19.6 21.4 17.3 19.6 17.8 20.6 22.0 18.4 55.0 115.4 93.1 36.6 22.4 25.2 18.8 27.4 27.3 43.8 34.4 23.0 135.6 74.4 33.8 86.5 106.3 50.7 20.1 27.0 3.9 22.7 6.7 31.6 24.8 51.8 31.2 70.5 71.4 31.1 17.7 31.3 25.5 56.4 31.6 62.8 74.3 98.3 18.0 63.9 62.0 31.1 10.2 28.4 14.3 7.8 41.0 18.9 23.2 46.9 18.3 52.6 16.5 60.8 75.8 30.0 35.6 51.1 19.7 23.1 55.3 33.7 45.6 32.4 46.0 40.7 37.9 27.4 43.8 21.0 28.4 15.1 28.2 81.4 35.6 21.7 TMEM254 "bA369J21.6, C10orf57, FLJ13263" ENSG00000133678 "Transmembrane protein 254" Q8TBM7 10 80078646-80092557 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029105, HPA072613" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 30: Epididymis - Antimicrobial activity" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Nucleoplasm "HPA029105: AB_2672909, HPA072613: AB_2732205" "unprognostic (9.40e-2)" "unprognostic (1.76e-1)" "unprognostic (9.52e-2)" "unprognostic (5.74e-3)" "unprognostic (5.39e-2)" "unprognostic (6.04e-2)" "unprognostic (3.66e-1)" "unprognostic (3.90e-1)" "unprognostic (1.64e-2)" "unprognostic (1.87e-3)" "unprognostic (3.68e-2)" "unprognostic (1.46e-1)" "unprognostic (7.65e-2)" "unprognostic (2.46e-1)" "unprognostic (1.21e-1)" "unprognostic (3.45e-3)" "unprognostic (5.96e-2)" 15.2 11.9 7.9 11.1 8.3 9.4 26.5 7.3 8.3 16.0 7.0 22.6 16.3 10.7 62.1 39.5 28.0 14.0 5.7 8.0 7.0 14.8 52.8 9.4 10.4 8.0 8.7 13.0 19.0 16.5 4.4 15.6 8.5 43.1 22.3 11.2 16.6 14.2 4.4 72.3 15.4 10.4 8.3 7.8 15.0 15.5 7.5 15.4 14.8 2.9 14.6 12.4 22.7 9.3 14.4 13.8 20.0 17.2 27.1 29.7 33.4 13.5 9.3 9.0 9.7 10.6 43.5 11.0 22.1 16.9 9.3 15.2 8.9 11.5 10.0 17.5 16.5 3.0 3.8 14.3 11.2 12.8 13.0 20.3 48.6 8.9 7.3 20.6 7.7 9.1 7.9 22.9 9.4 29.8 10.7 9.9 11.0 12.6 43.2 13.2 2.8 9.7 13.5 11.9 8.0 12.1 12.6 31.4 13.3 14.8 45.1 9.1 12.1 7.8 12.8 12.0 8.0 15.8 24.7 0.8 17.8 13.6 6.6 57.3 25.0 13.0 18.1 28.6 22.3 21.3 20.2 18.8 20.7 14.3 33.8 22.6 2.8 17.5 31.5 23.1 27.2 20.5 7.9 8.3 7.3 8.3 8.0 7.0 8.0 8.7 8.5 8.3 7.5 9.3 4.6 9.6 9.6 17.6 7.3 8.2 5.9 9.7 5.2 7.9 22.6 17.5 4.4 12.8 13.7 9.2 16.7 40.9 3.8 9.0 21.5 15.7 10.5 37.6 10.0 5.4 8.4 5.9 17.2 8.7 37.2 7.6 11.2 10.5 5.7 12.9 5.7 33.4 19.4 16.8 16.4 23.7 8.2 10.3 5.8 7.5 9.3 8.5 3.6 4.7 15.2 15.7 12.3 8.5 14.8 10.3 15.3 11.7 5.2 15.6 19.6 23.1 40.2 13.3 13.1 2.6 7.1 36.8 8.7 20.9 24.0 22.7 6.9 11.2 18.1 8.4 TMEM258 "C11orf10, Kud, Kuduk" ENSG00000134825 "Transmembrane protein 258" P61165 11 61768501-61792802 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA044602 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 22: Non-specific - Unknown function" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" Cytosol "Plasma membrane" "HPA044602: AB_10961423" "unprognostic (6.35e-2)" "unprognostic (1.70e-1)" "unprognostic (7.49e-2)" "unprognostic (4.99e-3)" "unprognostic (9.95e-2)" "unprognostic (1.24e-2)" "unprognostic (3.18e-2)" "unprognostic (1.24e-1)" "unprognostic (8.48e-2)" "prognostic favorable (4.37e-4)" "unprognostic (1.34e-3)" "unprognostic (7.39e-2)" "unprognostic (4.75e-3)" "unprognostic (2.59e-2)" "unprognostic (1.02e-1)" "unprognostic (3.34e-2)" "unprognostic (2.58e-1)" 116.4 158.4 125.5 66.1 128.7 128.4 120.8 130.8 162.2 142.2 123.0 112.4 80.9 116.0 350.1 122.8 123.1 59.3 170.8 122.6 128.7 123.5 160.6 110.0 83.0 130.0 125.6 154.9 300.3 80.5 128.9 80.4 130.3 105.5 107.6 44.0 183.9 88.7 146.7 95.3 99.8 81.5 131.1 124.4 142.8 79.1 126.8 111.7 109.1 120.6 108.9 107.5 111.7 140.1 144.3 254.9 194.9 173.3 329.0 308.4 117.1 113.9 177.1 104.5 124.8 223.5 265.5 103.9 205.9 272.1 196.1 154.8 186.7 222.7 149.1 141.7 168.6 86.8 258.3 347.6 310.7 186.9 96.3 272.5 339.6 137.1 364.8 267.9 210.9 207.4 221.7 394.5 185.4 501.1 131.2 318.8 267.1 315.6 172.9 142.1 144.6 673.0 241.5 243.7 169.3 173.1 103.8 221.7 211.5 179.6 244.5 347.3 108.0 129.2 111.7 166.1 78.3 248.6 201.7 173.6 183.8 112.6 135.7 507.9 225.6 287.6 169.5 200.4 216.5 233.2 198.8 190.1 177.8 187.1 167.1 166.7 182.4 151.7 204.4 496.4 236.8 244.9 125.5 128.7 130.8 162.2 122.6 128.7 130.0 125.6 130.3 131.1 126.8 140.1 211.3 102.5 224.1 6.8 323.6 228.9 220.5 794.5 170.8 41.3 525.1 608.3 491.3 403.2 445.9 318.2 18.8 409.5 279.8 306.2 295.4 534.8 234.4 369.2 304.7 254.8 311.1 197.7 7.4 654.4 667.7 314.8 210.5 305.6 226.7 261.8 335.2 572.9 461.4 37.0 8.2 631.5 441.5 401.7 396.9 142.8 335.5 265.7 569.2 3.7 430.0 418.6 270.8 6.0 25.8 469.4 432.6 214.4 821.3 296.6 392.2 553.8 470.9 73.9 170.9 192.3 248.5 399.4 433.8 297.4 279.0 508.0 245.2 135.3 442.1 274.9 TMEM266 "C15orf27, FLJ38190" ENSG00000169758 "Transmembrane protein 266" Q2M3C6 15 76059958-76229121 "Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 4 "brain: 8.4;skeletal muscle: 5.8;tongue: 2.2" "Cell type enhanced" "Detected in some" "Cone photoreceptor cells: 10.4;Cytotrophoblasts: 16.0;Early spermatids: 7.0;Late spermatids: 19.7;Rod photoreceptor cells: 9.1;Sertoli cells: 6.6;Spermatogonia: 6.3" "Cancer enhanced" "Detected in some" "testis cancer: 2.3" "Region enriched" "Detected in many" 5 "cerebellum: 8.4" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "NTERA-2: 1.3" "Region enriched" "Detected in all" 6 "cerebellum: 58.7" "Region enriched" "Detected in many" 5 "cerebellum: 26.8" "HPA041921, HPA049425" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 5: NTERA-2 - Transcription" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA041921: AB_10796789, HPA049425: AB_2732552" "unprognostic (8.63e-3)" "unprognostic (6.11e-3)" "unprognostic (3.44e-3)" "unprognostic (9.17e-5)" "unprognostic (4.67e-1)" "unprognostic (2.61e-2)" "unprognostic (9.34e-3)" "unprognostic (5.61e-2)" "unprognostic (8.48e-3)" "unprognostic (2.89e-2)" "unprognostic (1.18e-2)" "unprognostic (3.95e-2)" "unprognostic (1.68e-3)" "unprognostic (1.25e-1)" "unprognostic (1.31e-1)" "unprognostic (1.13e-2)" "unprognostic (7.86e-2)" 0.0 0.9 0.9 0.0 1.0 0.0 0.1 8.4 1.7 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.2 0.9 0.5 0.0 0.5 0.1 0.6 0.8 0.0 1.1 0.0 1.2 0.9 0.7 0.1 0.0 1.1 0.0 0.0 5.8 0.5 0.0 0.0 0.5 0.1 0.0 0.6 1.4 0.3 0.0 2.2 0.1 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.2 0.0 0.1 0.2 0.0 0.6 0.9 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.9 1.0 8.4 1.7 1.2 0.9 0.6 0.8 0.7 0.5 1.4 0.8 0.2 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 4.3 0.5 0.5 0.0 0.0 0.0 1.8 10.4 16.0 0.0 0.0 1.9 0.0 7.0 0.2 0.1 0.4 0.0 0.0 0.0 0.2 2.2 0.9 1.5 0.1 0.0 0.2 0.4 0.4 4.5 1.7 0.0 0.0 0.0 0.3 0.0 19.7 0.0 0.4 0.0 0.0 0.0 0.5 1.0 0.0 0.0 0.1 0.0 0.7 0.0 1.0 0.0 0.7 1.5 9.1 6.6 1.3 0.2 0.5 6.3 0.0 0.0 5.9 0.2 0.5 0.0 0.7 TMEM268 "C9orf91, DKFZp547P234, FLJ38045" ENSG00000157693 "Transmembrane protein 268" Q5VZI3 9 114611206-114646422 "Predicted membrane proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 2: 10.3;Breast glandular cells: 8.8;Endometrial stromal cells: 8.9;Glandular and luminal cells: 8.8;Granulosa cells: 9.6;Hofbauer cells: 8.9;monocytes: 19.1;Syncytiotrophoblasts: 8.8;Theca cells: 9.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 4.7" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in all" "Karpas-707: 51.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA017199 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 65: Brain - Ion transport" "Cluster 2: Karpas-707 - Immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA017199: AB_1845845" "unprognostic (8.57e-2)" "unprognostic (3.37e-1)" "unprognostic (8.33e-2)" "prognostic favorable (3.61e-4)" "unprognostic (2.09e-1)" "unprognostic (7.16e-2)" "unprognostic (3.55e-2)" "unprognostic (1.26e-1)" "unprognostic (1.87e-1)" "unprognostic (2.26e-2)" "unprognostic (2.22e-3)" "unprognostic (1.44e-1)" "unprognostic (6.67e-2)" "unprognostic (6.10e-2)" "unprognostic (7.65e-3)" "unprognostic (1.09e-2)" "unprognostic (1.47e-1)" 7.3 7.7 11.0 6.9 12.7 3.6 7.5 2.9 16.6 6.5 6.4 6.9 3.4 6.8 6.3 4.3 4.7 3.7 3.3 14.4 6.1 3.3 5.3 5.2 9.5 4.4 5.3 8.5 4.7 14.1 4.1 4.8 5.3 12.2 5.4 4.5 8.9 6.5 4.6 4.2 6.3 6.8 5.3 13.3 7.2 3.9 6.5 8.6 6.2 4.3 9.4 6.3 5.1 11.3 4.7 7.1 3.8 8.2 10.1 7.6 2.9 4.3 7.9 6.0 6.1 5.1 2.0 19.5 3.5 4.8 17.0 8.1 7.4 3.7 5.2 9.9 4.6 6.5 5.8 4.0 17.9 13.6 3.0 6.7 6.5 7.8 8.4 7.7 4.1 24.9 12.3 51.5 4.4 13.6 15.4 4.5 9.8 6.0 7.8 17.4 4.5 17.7 3.5 3.4 12.5 8.4 14.4 18.8 41.3 2.4 25.2 12.2 2.5 6.0 6.8 2.3 8.3 27.8 27.5 20.7 3.1 11.4 11.0 0.3 1.3 0.2 0.6 1.0 0.2 1.3 0.7 0.4 0.7 2.2 0.9 0.8 1.0 0.8 1.0 4.7 0.1 0.5 11.0 12.7 2.9 16.6 14.4 6.1 4.4 5.3 5.3 5.3 6.5 11.3 1.7 0.0 10.3 0.0 3.8 0.0 0.0 0.0 0.0 0.0 8.8 5.2 0.0 0.0 1.3 0.0 0.0 4.7 3.0 0.0 0.0 1.4 0.0 5.0 8.9 0.5 0.0 0.0 0.0 4.6 1.2 1.3 0.0 8.8 0.0 9.6 0.0 0.0 8.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.6 0.0 0.0 19.1 0.0 0.0 0.0 0.0 1.9 0.0 0.0 1.6 0.0 0.0 1.9 4.4 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 8.8 1.1 9.7 0.0 0.0 TMEM52 ENSG00000178821 "Transmembrane protein 52" Q8NDY8 1 1917590-1919279 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at transcript level" "Group enriched" "Detected in many" 5 "pancreas: 216.2;skeletal muscle: 298.9;tongue: 207.8" "Cell type enhanced" "Detected in many" "Exocrine glandular cells: 22.3;Hepatocytes: 25.9;Spermatocytes: 34.6;Spermatogonia: 39.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "Hep G2: 20.5;OE19: 18.2;RPMI-8226: 37.1" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA079372 Approved "Nucleoplasm,Plasma membrane" "Intracellular and membrane" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 59: Non-specific - Translation" "Cluster 25: RPMI-8226 - Immune response" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA079372: " "unprognostic (4.39e-2)" "unprognostic (2.60e-1)" "unprognostic (3.76e-2)" "unprognostic (7.35e-3)" "unprognostic (1.04e-5)" "unprognostic (1.46e-1)" "unprognostic (6.71e-3)" "unprognostic (3.68e-2)" "unprognostic (9.49e-2)" "unprognostic (1.69e-1)" "unprognostic (3.83e-3)" "unprognostic (5.80e-2)" "unprognostic (8.95e-2)" "unprognostic (1.18e-1)" "unprognostic (2.16e-1)" "unprognostic (1.15e-1)" "unprognostic (2.18e-2)" 1.9 52.6 1.9 0.2 2.1 0.5 2.0 2.1 3.7 1.1 3.0 2.5 3.6 0.6 0.4 6.9 3.3 0.4 1.8 1.8 1.9 2.4 13.5 1.9 0.4 1.8 2.1 2.2 216.2 3.1 1.7 0.2 1.7 1.8 1.3 0.2 19.8 0.4 298.9 3.5 2.3 0.3 1.5 2.8 6.9 29.2 1.8 0.4 0.8 207.8 0.3 0.6 2.1 1.7 3.4 0.3 0.9 1.8 0.3 0.1 7.5 0.5 0.2 2.2 1.3 5.6 2.3 0.8 2.2 3.5 0.8 1.1 5.5 1.5 0.4 0.4 4.0 0.0 0.9 20.5 1.1 0.0 1.3 0.1 3.1 0.7 0.3 0.1 0.1 3.9 5.1 1.9 0.0 6.4 0.5 1.5 2.9 18.2 10.6 1.5 0.0 37.1 1.2 0.2 3.7 2.6 0.0 3.1 0.4 1.3 2.1 0.4 0.0 0.0 1.4 1.0 0.0 2.4 0.8 1.1 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 1.9 2.1 2.1 3.7 1.8 1.9 1.8 2.1 1.7 1.5 1.8 1.7 0.4 0.0 0.0 0.0 1.2 4.5 2.9 1.2 2.8 0.4 3.9 5.2 0.8 8.6 2.4 0.0 0.0 1.9 0.8 6.8 1.9 1.8 3.9 3.8 0.3 0.8 0.0 0.4 0.6 22.3 7.0 1.6 5.1 0.8 0.0 5.1 0.7 25.9 0.6 0.0 0.5 11.1 8.2 0.8 2.2 5.8 14.9 0.7 8.8 0.0 0.6 1.8 0.0 0.0 0.1 6.7 2.5 9.8 4.3 14.2 15.4 11.5 8.7 1.0 0.0 15.4 1.6 34.6 39.4 2.5 2.8 3.7 1.2 15.5 7.1 3.1 TMEM63B "C6orf110, dJ421H19.2, DKFZp434P0531" ENSG00000137216 "Transmembrane protein 63B" Q5T3F8 6 44126914-44155519 "Predicted membrane proteins, Transporters" "Ion transport, Transport" "Ion channel" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Late spermatids: 87.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in all" "OE19: 163.7" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029249, HPA029250, HPA029251" Uncertain Enhanced "Plasma membrane,Actin filaments" NA NA "Cluster 40: NK-cells - Unknown function" "Cluster 39: Non-specific - Mitochondria" "Cluster 21: OE19 - Mitochondria" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Actin filaments" "HPA029249: AB_2672965, HPA029250: AB_2672966, HPA029251: AB_2672967" "unprognostic (8.83e-3)" "unprognostic (2.16e-2)" "unprognostic (2.42e-3)" "unprognostic (3.61e-1)" "unprognostic (2.89e-1)" "unprognostic (1.85e-1)" "unprognostic (6.97e-3)" "unprognostic (1.25e-2)" "unprognostic (1.87e-1)" "unprognostic (1.75e-1)" "unprognostic (8.60e-2)" "unprognostic (1.83e-1)" "unprognostic (1.17e-2)" "unprognostic (1.59e-1)" "unprognostic (2.67e-2)" "unprognostic (6.12e-3)" "unprognostic (3.15e-1)" 12.4 19.6 18.1 9.5 18.9 17.9 12.6 18.9 24.7 17.8 15.1 24.6 17.1 11.4 12.1 34.6 10.7 12.8 26.5 25.1 21.0 17.1 39.2 38.3 5.8 19.9 17.5 12.1 12.6 20.2 15.6 13.6 20.4 17.4 19.4 31.6 20.9 8.6 51.6 41.4 18.5 9.9 15.7 9.8 25.4 31.0 19.8 8.6 16.2 21.2 8.6 18.8 23.2 18.3 41.7 23.1 21.1 34.6 32.3 18.6 34.6 17.0 22.8 18.7 17.7 16.1 15.7 7.2 25.5 25.3 30.1 37.8 25.6 62.6 12.3 20.6 19.5 20.8 17.2 49.1 22.2 4.6 19.2 24.8 55.5 26.2 16.7 37.8 18.9 15.3 67.7 11.2 22.0 42.7 4.6 10.3 11.4 163.7 11.2 5.8 14.0 13.2 52.2 44.5 24.3 18.8 15.2 35.5 35.8 26.0 40.1 11.6 21.8 23.8 27.0 17.9 20.7 14.0 11.1 8.8 35.9 6.6 30.7 0.2 0.4 0.2 0.2 0.1 0.4 0.2 0.1 0.1 0.1 0.1 0.1 0.1 0.3 0.0 0.2 0.2 0.4 0.2 18.1 18.9 18.9 24.7 25.1 21.0 19.9 17.5 20.4 15.7 19.8 18.3 7.2 16.0 19.7 17.6 3.3 13.6 14.9 41.3 21.1 18.4 11.2 9.3 3.8 10.0 25.1 11.0 16.7 14.1 4.2 75.1 1.9 17.0 72.9 10.6 8.9 6.9 18.6 28.4 26.3 15.2 16.6 11.0 45.9 25.1 0.0 11.0 11.7 43.4 26.4 16.8 28.4 32.4 30.5 11.7 11.4 87.6 11.8 9.1 7.2 15.0 8.5 9.4 5.2 21.6 12.1 32.5 45.7 9.1 6.4 21.9 32.7 10.8 15.7 27.6 6.6 10.4 12.0 2.1 14.7 19.4 18.3 20.0 5.5 7.1 24.3 29.4 TMTC2 DKFZp762A217 ENSG00000179104 "Transmembrane O-mannosyltransferase targeting cadherins 2" Q8N394 12 82686880-83134870 "Enzymes, Predicted membrane proteins" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in many" 5 "brain: 60.8" "Cell type enriched" "Detected in many" 5 "Oligodendrocytes: 2152.4" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AF22: 32.0;WM-115: 80.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA026954, HPA026955" Uncertain Approved "Plasma membrane,Actin filaments" No No "Cluster 37: B-cells - Transcription" "Cluster 70: Brain - Nervous system development" "Cluster 17: WM-115 - Nervous system development" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane" "Actin filaments" "HPA026954: AB_2256025, HPA026955: AB_10602282" "unprognostic (1.56e-1)" "unprognostic (5.62e-2)" "unprognostic (9.61e-2)" "unprognostic (7.38e-2)" "unprognostic (2.60e-2)" "unprognostic (3.66e-2)" "unprognostic (1.05e-2)" "unprognostic (1.58e-1)" "unprognostic (1.25e-1)" "unprognostic (7.16e-2)" "unprognostic (1.73e-3)" "unprognostic (5.06e-2)" "prognostic favorable (2.84e-5)" "unprognostic (1.10e-1)" "unprognostic (1.60e-1)" "unprognostic (2.06e-2)" "unprognostic (8.06e-2)" 3.7 0.8 11.4 4.7 39.8 2.1 4.6 21.4 25.1 4.8 0.0 11.7 2.8 5.4 4.4 9.8 10.0 7.8 2.0 11.2 19.1 6.6 1.2 6.4 1.8 28.3 29.9 1.9 4.5 2.8 3.5 3.4 26.7 6.1 5.7 5.5 6.9 11.2 1.2 5.2 4.7 6.8 11.7 1.3 10.2 3.0 26.8 1.5 6.4 1.7 2.2 7.5 7.3 60.8 1.7 6.4 32.0 0.2 4.3 3.9 2.9 2.1 0.7 1.7 0.3 0.3 3.4 0.0 0.5 11.9 1.2 2.8 9.7 4.9 0.5 7.5 5.8 0.0 5.2 0.2 0.4 2.2 1.0 1.1 4.3 0.2 1.6 3.4 2.7 3.5 0.0 4.2 0.4 3.4 1.6 8.8 1.1 6.0 5.3 0.0 1.3 0.6 2.9 14.1 8.3 15.1 2.9 4.6 21.0 5.4 4.9 0.5 1.7 5.3 1.8 7.2 2.7 7.8 5.7 1.2 1.2 3.8 80.2 0.0 0.9 0.0 0.0 0.3 0.0 0.3 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.2 11.4 39.8 21.4 25.1 11.2 19.1 28.3 29.9 26.7 11.7 26.8 60.8 10.7 9.6 8.9 333.3 2.0 14.4 15.5 12.0 18.2 38.1 8.9 5.5 1.8 11.5 18.4 14.7 8.4 13.6 3.1 3.6 0.0 5.4 12.9 13.5 7.5 10.3 2.4 0.8 117.1 8.2 1.7 9.8 12.8 13.1 0.0 0.2 2.5 1.4 1.9 8.4 377.0 9.8 2.0 6.6 9.6 5.0 5.9 6.2 32.0 86.2 9.3 13.9 1.0 38.7 2152.4 9.4 3.3 1.2 7.3 11.9 2.7 2.1 17.0 1.6 6.6 0.8 2.2 0.6 2.2 16.2 11.5 4.1 2.8 1.0 5.9 14.5 TNFRSF10D "CD264, DcR2, TRAILR4, TRUNDD" ENSG00000173530 "TNF receptor superfamily member 10d" Q9UBN6 8 23135588-23164027 "Cancer-related genes, CD markers, Predicted membrane proteins" Apoptosis Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Adipocytes: 114.4;Endothelial cells: 52.3;Gastric mucus-secreting cells: 83.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 99.5;LHCN-M2: 250.4;WM-115: 238.4" HPA070971 Approved "Plasma membrane,Actin filaments" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 17: WM-115 - Nervous system development" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Actin filaments" "HPA070971: AB_2686330" "unprognostic (1.49e-1)" "prognostic unfavorable (1.70e-4)" "unprognostic (1.41e-1)" "unprognostic (8.78e-2)" "unprognostic (8.13e-2)" "unprognostic (7.49e-2)" "unprognostic (2.69e-1)" "unprognostic (7.06e-2)" "unprognostic (3.56e-2)" "unprognostic (1.66e-1)" "unprognostic (1.61e-2)" "unprognostic (1.32e-1)" "unprognostic (2.12e-2)" "unprognostic (2.70e-1)" "unprognostic (1.35e-2)" "unprognostic (6.32e-2)" "unprognostic (1.72e-1)" 10.6 2.3 4.8 5.3 4.8 9.0 4.8 4.5 6.1 3.7 6.1 6.1 4.4 4.7 3.7 2.6 5.9 7.9 6.2 4.4 4.6 12.1 17.6 10.0 3.5 4.9 4.7 7.1 3.5 1.9 2.8 2.9 5.1 4.6 7.3 0.5 2.2 2.9 1.4 2.1 6.9 7.7 5.2 5.0 5.5 3.0 6.1 1.8 3.8 1.0 4.1 3.9 3.1 5.0 15.1 12.7 16.3 9.4 12.2 47.7 0.3 78.2 29.5 5.8 7.9 24.4 12.2 0.0 16.1 47.1 0.0 5.0 13.7 68.6 50.3 0.1 12.1 4.2 7.7 21.2 52.7 2.7 5.3 60.1 75.0 20.6 14.0 71.4 99.5 0.6 0.0 0.1 250.4 0.0 0.0 8.2 13.2 44.1 0.1 3.0 0.1 3.8 19.0 6.8 0.3 0.1 8.4 0.0 0.0 36.1 0.1 9.9 59.4 0.1 0.0 4.7 0.1 0.0 0.0 0.0 63.3 4.0 238.4 2.5 2.1 0.9 0.0 0.8 0.1 1.3 1.9 0.6 2.9 0.4 5.2 2.1 1.4 0.2 1.4 0.0 0.6 1.5 4.8 4.8 4.5 6.1 4.4 4.6 4.9 4.7 5.1 5.2 6.1 5.0 114.4 0.0 9.8 0.3 7.0 5.0 4.1 11.3 14.8 0.0 6.0 12.8 3.5 1.5 10.2 1.8 0.0 0.1 1.2 6.8 0.0 5.7 0.4 6.4 5.8 52.3 1.8 0.0 0.1 2.2 0.3 19.2 83.6 9.5 7.6 1.5 16.1 8.2 2.9 0.0 0.1 5.6 6.1 6.1 9.8 0.1 0.3 13.0 8.8 19.7 3.5 0.3 0.0 0.5 0.1 12.3 3.1 0.4 6.8 4.9 6.8 2.8 6.4 0.2 0.0 11.9 14.3 0.8 2.3 4.5 2.4 0.1 5.9 2.1 6.9 3.7 TNFRSF11A "CD265, FEO, LOH18CR1, PDB2, RANK" ENSG00000141655 "TNF receptor superfamily member 11a" Q9Y6Q6 18 62325287-62391288 "CD markers, Disease related genes, Human disease related genes, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Deafness, Disease variant, Osteopetrosis" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "intestine: 30.5;salivary gland: 25.4" "Cell type enhanced" "Detected in many" "Distal enterocytes: 35.6;Intestinal goblet cells: 24.0;Paneth cells: 42.3;Proximal enterocytes: 25.5;Undifferentiated cells: 42.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enriched" "Detected in single" 8 "NK-cell: 5.3" "Lineage enriched" "Detected in single" 8 "NK-cells: 5.3" "Cell line enriched" "Detected in many" 6 "HDLM-2: 125.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "CAB010391, HPA047976" Approved Supported "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 110000 "Cluster 48: NK-cells - Unknown function" "Cluster 56: Intestine - Transmembrane transport" "Cluster 44: HDLM-2 - Immune response" "Cluster 53: Intestinal epithelial cells - Unknown function" "Plasma membrane" Cytosol "CAB010391: AB_2205352, HPA047976: AB_2680227" "unprognostic (4.08e-1)" "unprognostic (2.71e-1)" "unprognostic (3.23e-3)" "unprognostic (1.73e-1)" "unprognostic (6.03e-2)" "unprognostic (1.35e-1)" "unprognostic (9.96e-4)" "unprognostic (4.24e-3)" "unprognostic (7.79e-4)" "unprognostic (1.52e-1)" "unprognostic (4.05e-2)" "unprognostic (2.88e-1)" "unprognostic (4.69e-5)" "unprognostic (1.56e-1)" "unprognostic (1.78e-1)" "unprognostic (4.02e-2)" "unprognostic (7.07e-2)" 1.8 1.1 0.8 5.7 1.6 0.4 4.1 0.1 1.9 1.4 0.3 17.1 30.5 0.9 0.3 2.8 0.9 7.6 0.6 2.0 1.1 0.4 0.6 1.0 1.2 0.7 1.1 0.4 1.7 0.9 6.8 3.2 0.2 1.3 17.6 0.2 25.4 2.7 0.3 2.7 18.6 1.7 0.7 0.8 5.5 0.9 1.2 1.0 1.2 0.1 1.9 1.6 1.6 2.1 3.2 2.2 0.1 0.0 0.1 0.0 0.1 0.1 0.0 0.1 1.6 0.4 0.6 0.0 3.5 0.4 1.4 2.2 8.3 0.9 0.2 125.9 5.4 0.0 1.3 1.7 0.0 0.5 1.3 0.2 0.4 0.8 3.1 4.2 3.1 0.3 0.0 0.0 0.0 1.1 0.0 0.1 5.9 7.0 19.3 0.4 0.0 0.6 1.5 1.5 20.4 0.7 0.6 3.0 0.1 0.8 1.3 0.4 2.0 0.0 0.1 0.1 0.0 1.2 0.0 0.1 0.3 0.0 4.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 5.3 0.0 0.3 0.6 0.0 0.8 1.6 0.1 1.9 2.0 1.1 0.7 1.1 0.2 0.7 1.2 2.1 0.4 0.0 2.2 0.0 0.4 1.3 3.8 1.1 0.6 0.6 4.5 3.3 1.3 8.6 2.3 0.0 0.0 0.1 3.3 35.6 0.0 8.3 0.3 3.2 0.5 5.3 10.8 0.0 4.0 7.5 0.6 0.7 11.7 6.2 0.0 2.0 7.1 0.3 15.5 3.3 0.2 24.0 0.0 17.0 2.4 0.4 0.6 7.7 1.8 8.4 19.7 0.0 3.1 0.5 0.4 14.7 42.3 0.0 0.5 2.8 25.5 0.0 3.8 0.2 0.0 0.5 0.4 0.8 1.9 1.7 2.3 0.1 0.7 0.0 42.2 4.4 TNFRSF12A "CD266, FN14, TweakR" ENSG00000006327 "TNF receptor superfamily member 12A" Q9NP84 16 3018445-3022383 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" "Angiogenesis, Apoptosis, Cell adhesion, Differentiation" "Developmental protein, Receptor" "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Basal keratinocytes: 612.4;Basal prostatic cells: 1315.6;Basal respiratory cells: 622.2;Ductal cells: 938.2;Exocrine glandular cells: 698.4;Pancreatic endocrine cells: 1232.3;Prostatic glandular cells: 757.9;Urothelial cells: 695.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in many" 8 "eosinophil: 139.6;neutrophil: 102.9" "Lineage enriched" "Detected in many" 10 "granulocytes: 139.6" "Cell line enhanced" "Detected in many" "U-251 MG: 699.6" HPA007853 Approved Approved "Plasma membrane,Cytosol" NA Yes 370000 "Cluster 52: Eosinophils - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 18: U-2197 - ECM organization" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA007853: AB_1858463" "unprognostic (1.44e-1)" "unprognostic (2.46e-3)" "unprognostic (8.90e-2)" "unprognostic (2.60e-1)" "unprognostic (4.06e-3)" "prognostic unfavorable (5.50e-4)" "unprognostic (7.04e-3)" "unprognostic (1.98e-3)" "unprognostic (4.17e-3)" "unprognostic (2.85e-1)" "unprognostic (5.02e-3)" "unprognostic (3.88e-1)" "prognostic unfavorable (8.78e-4)" "unprognostic (2.98e-2)" "unprognostic (6.00e-2)" "unprognostic (2.80e-3)" "unprognostic (2.17e-2)" 42.0 45.9 5.3 27.0 5.2 8.3 24.4 6.1 9.9 12.5 9.4 26.5 37.5 34.8 1.2 17.6 19.0 55.2 108.3 5.6 8.8 133.5 61.0 72.6 2.4 8.2 7.9 8.2 116.3 56.1 59.3 33.0 7.0 33.4 4.5 4.8 48.4 17.1 58.5 18.1 21.6 32.5 7.4 6.7 42.6 5.4 10.4 5.2 37.0 9.3 3.1 73.8 13.9 7.0 217.6 155.6 17.7 31.9 31.0 71.3 109.1 444.3 277.5 316.2 205.5 70.1 336.0 1.5 566.2 270.4 401.3 224.2 4.2 283.4 132.2 8.3 11.2 1.5 52.4 58.4 205.1 3.7 15.2 65.2 196.7 345.1 433.5 298.1 100.9 0.6 24.5 2.4 362.7 394.0 0.6 28.3 85.5 88.7 369.6 1.9 207.1 7.8 355.8 37.6 19.9 7.3 314.7 127.9 255.8 57.7 69.4 5.8 192.2 601.9 303.2 423.8 699.6 6.6 2.9 3.1 190.0 18.9 488.8 12.2 11.4 139.6 6.1 7.3 7.9 0.2 2.8 4.9 14.6 0.2 1.4 2.7 102.9 8.0 4.7 0.6 3.4 4.0 5.3 5.2 6.1 9.9 5.6 8.8 8.2 7.9 7.0 7.4 10.4 7.0 16.9 102.5 37.7 0.3 6.9 612.4 1315.6 622.2 113.3 1.5 139.0 46.7 63.9 195.9 238.7 182.1 2.1 134.6 10.0 74.2 64.6 938.2 1.3 170.5 29.4 47.5 27.3 1.3 0.2 698.4 169.5 155.1 33.1 173.1 59.1 3.0 24.3 20.7 39.7 0.0 0.5 19.9 152.5 5.6 121.4 0.8 6.2 23.0 112.1 1.9 10.8 23.3 4.1 0.0 0.1 1232.3 155.3 6.8 5.3 757.9 52.9 118.0 118.4 5.9 6.6 190.5 228.6 10.9 9.4 35.5 359.7 189.1 25.3 1.3 50.0 695.6 TNFRSF21 "CD358, DR6" ENSG00000146072 "TNF receptor superfamily member 21" O75509 6 47231532-47309905 "CD markers, Metabolic proteins, Plasma proteins, Predicted membrane proteins" "Adaptive immunity, Apoptosis, Host-virus interaction, Immunity" Receptor "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "urinary bladder: 148.1" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 179.9;Prostatic glandular cells: 180.8;Syncytiotrophoblasts: 178.7;Urothelial cells: 387.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 35 "plasmacytoid DC: 69.2" "Lineage enriched" "Detected in single" 303 "dendritic cells: 69.2" "Cell line enhanced" "Detected in many" "OE19: 208.0;RT4: 523.8;SuSa: 213.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006746, CAB009805" Approved Supported "Plasma membrane,Cytosol" NA NA 2300000 "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 70: Brain - Nervous system development" "Cluster 15: RT4 - Unknown function" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "CAB009805: AB_2206956, HPA006746: AB_1078701" "unprognostic (1.19e-2)" "unprognostic (2.70e-1)" "unprognostic (3.26e-1)" "unprognostic (7.85e-2)" "unprognostic (1.44e-1)" "unprognostic (3.41e-2)" "unprognostic (9.80e-3)" "unprognostic (1.11e-1)" "unprognostic (1.46e-2)" "unprognostic (7.53e-2)" "unprognostic (1.38e-3)" "unprognostic (1.74e-1)" "prognostic favorable (7.23e-6)" "unprognostic (1.48e-1)" "unprognostic (1.34e-1)" "unprognostic (9.78e-2)" "unprognostic (1.45e-2)" 55.7 6.6 17.6 17.7 31.0 13.4 13.4 48.9 31.4 17.5 1.1 38.1 12.3 17.1 2.5 41.3 16.4 35.7 9.8 21.8 27.4 49.6 8.9 16.9 17.2 76.8 43.8 6.5 20.0 58.8 6.5 33.2 56.9 13.7 34.8 4.1 25.6 4.0 6.0 4.0 19.2 15.7 43.7 14.9 60.8 8.1 49.0 26.8 4.0 14.1 32.9 148.1 17.1 100.1 156.6 50.0 47.7 15.3 127.4 37.5 53.9 17.9 34.9 5.5 2.1 86.7 107.7 11.6 70.3 13.1 101.8 92.2 7.2 66.1 3.1 0.2 15.1 0.1 6.4 88.2 74.6 2.5 0.6 67.1 77.2 3.3 58.1 4.2 25.8 10.1 3.8 0.1 1.9 30.8 13.9 1.4 37.5 208.0 50.8 29.1 14.7 17.1 90.8 523.8 34.1 7.5 15.6 14.4 12.9 213.0 11.1 11.0 5.2 14.1 12.9 0.5 16.5 0.1 0.2 16.1 23.1 11.1 40.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.1 0.0 0.0 0.1 0.1 0.1 69.2 0.0 0.6 17.6 31.0 48.9 31.4 21.8 27.4 76.8 43.8 56.9 43.7 49.0 100.1 5.5 0.0 9.8 1.6 3.1 23.7 179.9 140.5 64.9 1.1 8.0 10.8 10.2 35.8 59.9 1.8 0.0 31.0 77.3 100.7 15.6 86.8 55.0 12.0 17.3 8.6 12.0 3.0 46.6 29.6 21.4 32.9 80.5 13.8 19.7 2.1 1.1 0.3 22.4 0.0 29.6 42.9 107.8 53.6 12.5 40.3 2.8 22.6 12.4 13.1 0.6 5.4 0.0 53.3 44.7 89.1 54.5 1.2 2.0 180.8 14.7 51.3 54.7 1.4 78.9 21.5 24.2 1.0 3.7 40.4 9.9 178.7 2.8 13.1 19.9 387.3 TNFRSF9 "4-1BB, CD137, ILA" ENSG00000049249 "TNF receptor superfamily member 9" Q07011 1 7915871-7943165 "Cancer-related genes, CD markers, Predicted intracellular proteins, Predicted membrane proteins" Receptor "Cancer-related genes" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 4 "lymphoid tissue: 9.9" "Cell type enhanced" "Detected in some" "dendritic cells: 15.0;granulocytes: 63.4;Langerhans cells: 17.5;monocytes: 31.6;T-cells: 29.2" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in some" "Group enriched" "Detected in many" 5 "memory CD8 T-cell: 9.4;neutrophil: 7.8;NK-cell: 5.2;T-reg: 18.5" "Group enriched" "Detected in many" 5 "granulocytes: 7.8;NK-cells: 5.2;T-cells: 18.5" "Cell line enriched" "Detected in some" 9 "HDLM-2: 111.5" "Not detected" "Not detected" "Low region specificity" "Detected in some" HPA071425 Approved "Nucleoli,Plasma membrane" NA NA "Cluster 35: T-regs - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 44: HDLM-2 - Immune response" "Cluster 24: Non-specific - Transcription regulation" "Plasma membrane" Nucleoli "HPA071425: AB_2686394" "unprognostic (7.23e-2)" "unprognostic (1.72e-2)" "unprognostic (8.26e-3)" "unprognostic (1.32e-3)" "unprognostic (1.10e-1)" "unprognostic (1.98e-2)" "unprognostic (2.52e-1)" "unprognostic (1.04e-1)" "unprognostic (1.19e-4)" "unprognostic (9.47e-3)" "unprognostic (2.17e-2)" "unprognostic (2.02e-1)" "prognostic unfavorable (2.69e-8)" "unprognostic (1.64e-2)" "unprognostic (2.25e-2)" "unprognostic (1.19e-1)" "unprognostic (9.55e-2)" 0.5 0.2 0.4 3.9 0.4 2.2 0.2 1.1 0.5 0.2 0.3 0.5 0.5 0.3 0.2 0.6 0.1 1.6 0.2 0.4 0.1 0.2 0.7 0.8 9.0 0.3 0.1 0.2 0.7 0.0 0.0 0.2 0.3 0.3 1.1 0.5 0.3 0.2 0.2 0.5 0.8 0.2 0.0 4.1 0.8 0.2 0.3 3.7 0.2 0.2 9.9 1.9 0.0 1.1 2.5 0.9 0.2 0.2 0.0 0.1 0.1 0.1 0.4 0.5 0.5 3.1 0.5 0.1 1.2 0.1 1.8 0.4 0.0 0.4 1.9 111.5 0.2 0.6 0.5 0.1 1.8 0.0 0.9 0.3 0.7 0.5 0.2 0.4 0.1 0.1 0.4 0.3 0.1 0.2 0.0 0.3 0.1 0.1 0.2 0.1 0.7 0.2 0.3 0.1 0.2 0.2 0.4 0.2 0.0 1.3 0.1 0.3 0.3 0.3 3.2 0.1 0.5 0.2 0.2 0.2 13.0 0.8 0.1 1.5 1.9 0.2 1.7 0.6 0.3 0.3 1.1 9.4 1.4 0.4 0.2 1.7 7.8 5.2 0.1 0.3 18.5 1.4 0.4 0.4 1.1 0.5 0.4 0.1 0.3 0.1 0.3 0.0 0.3 1.1 0.6 0.0 1.7 0.0 1.6 0.3 0.9 0.3 0.6 0.0 0.3 0.5 0.4 0.0 1.9 0.0 0.0 0.0 15.0 0.1 0.0 1.3 0.0 0.6 1.0 0.8 0.0 0.0 0.2 1.1 0.0 1.0 3.6 1.4 63.4 0.0 0.0 0.0 0.8 0.0 0.3 0.2 0.0 0.3 17.5 0.0 0.0 3.6 5.4 0.0 31.6 0.0 1.0 0.0 0.1 2.0 0.1 0.0 9.4 0.5 0.0 0.1 0.0 0.0 0.0 7.7 1.0 0.4 0.1 0.1 0.4 0.0 29.2 0.0 0.5 0.3 TNK2 "ACK, ACK1, p21cdc42Hs" ENSG00000061938 "Tyrosine kinase non receptor 2" Q07912 3 195863364-195911945 "Cancer-related genes, Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" Endocytosis "Kinase, Serine/threonine-protein kinase, Transferase, Tyrosine-protein kinase" "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "brain: 102.9" "Cell type enhanced" "Detected in many" "Horizontal cells: 99.3;Oligodendrocyte precursor cells: 245.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041954, HPA069561" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" Vesicles "HPA041954: AB_10794164, HPA069561: " "unprognostic (1.97e-2)" "unprognostic (1.05e-1)" "unprognostic (1.15e-3)" "prognostic unfavorable (8.96e-4)" "unprognostic (1.34e-1)" "unprognostic (8.92e-2)" "unprognostic (1.45e-1)" "unprognostic (1.30e-1)" "unprognostic (8.89e-3)" "unprognostic (1.13e-1)" "unprognostic (8.92e-3)" "unprognostic (4.49e-2)" "prognostic unfavorable (1.30e-4)" "unprognostic (6.82e-2)" "unprognostic (9.76e-2)" "unprognostic (1.44e-1)" "prognostic favorable (1.00e-4)" 14.2 10.0 77.1 24.7 64.1 72.2 15.0 40.0 102.9 18.0 11.8 18.5 9.4 13.8 11.1 19.1 17.1 10.5 18.4 75.6 51.4 7.7 10.5 14.1 30.0 77.5 59.8 13.4 12.1 6.1 36.4 12.7 70.1 21.1 6.3 9.3 26.3 11.8 54.8 62.3 16.1 9.2 45.5 27.0 19.7 12.0 57.0 16.0 10.0 16.7 20.1 19.4 19.3 60.6 93.4 16.3 15.4 13.4 15.3 11.5 80.0 17.7 16.7 11.7 9.4 15.6 79.3 25.9 55.1 24.2 17.4 34.1 14.9 22.2 3.5 61.8 15.4 22.0 36.2 10.4 7.9 13.5 10.2 7.8 30.7 11.7 17.9 26.7 13.3 9.2 11.3 30.6 9.4 67.1 5.3 39.7 12.3 24.6 29.1 13.8 15.6 26.0 7.2 51.2 16.2 16.5 9.5 37.6 21.3 11.3 71.4 11.9 18.9 19.1 13.0 11.4 48.6 70.8 9.2 17.0 22.1 38.0 15.4 1.4 1.2 0.3 0.9 1.5 0.4 1.3 0.8 0.4 0.5 2.5 0.5 0.5 2.7 0.4 1.4 1.5 0.1 0.7 77.1 64.1 40.0 102.9 75.6 51.4 77.5 59.8 70.1 45.5 57.0 60.6 9.3 6.4 7.7 44.4 14.6 6.9 8.1 6.0 4.6 30.6 13.0 12.6 16.1 7.2 8.9 0.0 50.1 13.4 11.0 18.0 1.9 4.0 1.0 4.1 5.4 11.1 6.1 12.8 42.7 5.3 3.3 4.6 14.3 4.1 1.3 4.5 11.7 19.2 8.1 99.3 45.3 2.3 6.1 16.0 11.7 1.2 6.5 13.7 5.4 20.6 16.2 5.9 21.6 245.3 25.1 29.5 9.6 6.4 10.7 8.2 0.9 1.6 7.6 20.3 0.0 4.8 5.7 6.4 11.2 11.0 10.5 4.2 12.5 1.7 6.4 19.0 TNNI2 "AMCD2B, DA2B, FSSV" ENSG00000130598 "Troponin I2, fast skeletal type" P48788 11 1838981-1841680 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Actin-binding, Muscle protein" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 25 "skeletal muscle: 7969.8;tongue: 2622.3" "Group enriched" "Detected in many" 6 "Extravillous trophoblasts: 449.4;Skeletal myocytes: 598.7" "Group enriched" "Detected in many" 10 "cervical cancer: 12.7;head and neck cancer: 33.6;pancreatic cancer: 12.9;urothelial cancer: 39.8" "Not detected" "Not detected" "Immune cell enhanced" "Detected in many" "plasmacytoid DC: 86.4" "Low lineage specificity" "Detected in many" "Group enriched" "Detected in some" 6 "CAPAN-2: 35.7;hTCEpi: 101.2" "Region enriched" "Detected in single" 6 "olfactory bulb: 5.1" "Not detected" "Not detected" "CAB018697, HPA055938" Enhanced Approved "Plasma membrane,Intermediate filaments" NA NA 110000 "Cluster 52: Eosinophils - Transcription" "Cluster 33: Striated muscle - Muscle contraction" "Cluster 30: Epithelial cell lines - Translation" "Cluster 37: Myocytes - Muscle contraction" "Plasma membrane" "Intermediate filaments" "CAB018697: AB_628400, HPA055938: AB_2682976" "unprognostic (2.03e-2)" "unprognostic (1.13e-1)" "unprognostic (1.29e-2)" "unprognostic (3.70e-1)" "unprognostic (1.85e-1)" "unprognostic (1.02e-2)" "unprognostic (9.99e-3)" "unprognostic (1.01e-1)" "unprognostic (1.73e-1)" "unprognostic (1.51e-1)" "unprognostic (1.10e-1)" "unprognostic (2.70e-1)" "unprognostic (1.23e-3)" "unprognostic (5.92e-3)" "unprognostic (5.62e-2)" "unprognostic (1.77e-1)" "unprognostic (2.79e-2)" 3.0 1.8 0.3 1.1 0.3 6.1 7.9 0.3 0.6 1.0 0.4 1.2 0.3 0.8 0.3 66.9 0.9 5.6 1.7 0.3 0.4 0.7 1.6 7.8 1.6 0.4 0.4 0.7 8.8 0.0 0.9 3.0 0.4 14.0 0.2 0.0 216.1 3.2 7969.8 55.2 2.7 0.2 0.4 5.8 1.1 0.7 0.5 1.9 2.8 2622.3 1.0 27.4 3.2 0.6 0.0 0.0 0.1 0.1 0.0 0.0 0.7 0.0 0.0 0.0 0.0 2.4 35.7 1.0 0.2 0.0 0.0 1.7 0.0 1.3 0.0 0.0 0.0 0.1 0.0 2.1 0.2 0.0 0.1 8.1 101.2 0.0 2.4 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.4 0.0 3.1 0.0 0.1 1.2 2.4 0.0 1.0 0.0 1.0 0.0 0.7 0.0 0.0 12.3 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.0 0.4 0.0 0.6 0.0 13.8 5.8 53.3 0.1 12.5 0.1 3.8 0.0 0.0 8.0 4.8 0.0 0.0 39.7 0.4 17.6 86.4 0.0 2.5 0.3 0.3 0.3 0.6 0.3 0.4 0.4 0.4 0.4 0.4 0.5 0.6 1.2 3.2 4.4 0.0 9.1 25.1 2.6 1.8 15.4 0.0 0.5 23.7 5.6 21.5 3.0 0.0 0.0 33.8 15.7 0.1 0.0 1.4 0.0 1.4 0.2 2.0 0.0 0.0 0.0 0.6 449.4 2.4 1.1 0.1 10.8 0.4 0.4 0.3 39.6 0.0 0.0 0.0 2.0 18.8 10.7 0.0 0.3 25.9 0.0 0.0 16.0 0.0 1.0 0.0 0.0 1.4 0.0 0.0 4.2 0.1 0.0 0.2 13.2 0.0 0.0 598.7 2.4 0.0 0.6 2.7 6.5 87.2 1.9 4.3 0.0 0.9 TOGARAM2 "Crescerin-2, FAM179A, FLJ43249, LOC165186" ENSG00000189350 "TOG array regulator of axonemal microtubules 2" Q6ZUX3 2 28956611-29052230 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Group enriched" "Detected in many" 9 "brain: 34.9;choroid plexus: 25.2;fallopian tube: 20.1" "Group enriched" "Detected in some" 4 "dendritic cells: 20.1;Endometrial ciliated cells: 65.4;Respiratory ciliated cells: 30.6" "Not detected" "Not detected" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "gdT-cell: 1.6" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "HMC-1: 2.3;JURKAT: 1.2;NB-4: 1.3" "Low region specificity" "Detected in many" "HPA037561, HPA037562, HPA075216" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 88: Choroid plexus - Transmembrane transport" "Cluster 3: HMC-1 - Innate immune response" "Cluster 49: Ciliated cells - Cilium organization" "Nucleoplasm, Plasma membrane" "HPA037561: AB_10670384, HPA037562: AB_2675545, HPA075216: " "unprognostic (8.35e-5)" "unprognostic (2.85e-3)" "unprognostic (1.41e-1)" "unprognostic (7.01e-3)" "unprognostic (6.41e-2)" "unprognostic (1.23e-2)" "unprognostic (1.11e-1)" "unprognostic (2.53e-3)" "unprognostic (3.93e-1)" "unprognostic (6.83e-2)" "unprognostic (2.32e-3)" "unprognostic (5.92e-2)" "unprognostic (3.94e-11)" "unprognostic (3.75e-2)" "unprognostic (4.46e-1)" "unprognostic (2.01e-2)" "unprognostic (2.81e-3)" 0.1 1.2 4.5 0.6 11.5 1.9 0.2 10.6 2.3 0.5 25.2 0.3 0.5 0.6 0.1 0.4 20.1 0.3 2.8 4.5 7.6 0.1 0.2 2.8 0.8 19.2 34.9 0.5 0.3 0.0 1.1 0.3 17.3 0.2 0.2 0.2 0.2 0.1 1.2 0.3 0.4 0.5 12.5 2.0 1.0 1.3 10.6 0.2 0.1 3.0 0.7 0.2 0.1 5.3 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.7 0.2 0.7 0.0 0.0 0.0 0.1 0.0 0.1 0.2 0.1 0.0 0.2 0.1 0.7 0.0 0.6 0.1 0.2 0.6 2.3 0.1 0.0 0.0 0.0 0.2 0.1 1.2 0.0 0.3 0.3 0.0 0.3 1.3 1.0 0.4 0.1 0.0 0.3 0.6 0.3 0.0 0.8 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 0.0 0.6 0.4 0.0 0.0 0.0 0.0 1.6 0.0 0.7 0.0 0.1 1.1 0.0 0.0 0.0 0.5 0.0 0.6 0.0 0.0 0.6 0.5 4.5 11.5 10.6 2.3 4.5 7.6 19.2 34.9 17.3 12.5 10.6 5.3 0.3 0.0 3.6 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 5.6 0.0 0.0 0.0 20.1 0.0 0.0 0.0 0.0 65.4 1.1 0.0 0.0 0.0 0.0 0.0 0.1 1.6 0.0 1.7 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 7.9 0.0 0.0 0.2 30.6 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.3 3.6 0.5 0.0 0.0 TOR2A "FLJ14771, TORP1" ENSG00000160404 "Torsin family 2 member A" "Q5JU69, Q8N2E6" 9 127731524-127735313 "Predicted secreted proteins" Hormone "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 69.1;Theca cells: 114.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071229 Approved Uncertain "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 18: Non-specific - Mitochondria" "Cluster 6: T47d - Mammary gland" "Cluster 52: Non-specific - Transcription" "Endoplasmic reticulum, Plasma membrane" "HPA071229: AB_2732175" "unprognostic (1.67e-1)" "unprognostic (9.19e-3)" "unprognostic (1.47e-1)" "unprognostic (1.27e-3)" "unprognostic (3.04e-2)" "unprognostic (6.97e-2)" "unprognostic (2.43e-3)" "unprognostic (4.83e-2)" "unprognostic (1.44e-1)" "unprognostic (1.33e-1)" "unprognostic (6.51e-3)" "unprognostic (1.05e-2)" "unprognostic (6.98e-2)" "prognostic favorable (7.51e-4)" "unprognostic (1.72e-1)" "unprognostic (3.27e-1)" "unprognostic (2.82e-2)" 6.8 10.7 9.6 6.8 9.3 26.9 6.7 9.4 13.2 7.9 9.5 12.2 11.2 6.7 3.4 11.4 7.0 4.9 5.4 9.2 9.1 10.2 14.0 8.7 7.7 9.4 9.2 8.2 13.6 3.1 10.0 7.9 8.9 8.1 5.4 2.9 8.7 3.6 3.3 9.5 12.8 2.7 8.6 20.8 11.8 20.4 9.7 8.4 8.7 2.2 4.5 7.1 7.1 9.1 7.4 11.5 9.7 12.2 4.7 4.6 13.0 5.1 6.3 8.0 6.3 7.9 12.6 13.6 7.5 4.4 6.0 23.2 3.0 6.4 2.2 21.1 11.0 5.2 10.6 9.7 7.7 11.0 27.0 7.4 11.8 7.4 3.9 4.0 11.5 16.2 16.2 37.3 4.7 43.4 14.3 34.7 8.7 24.0 9.9 23.4 4.5 30.9 8.3 6.9 21.0 8.3 4.7 16.6 5.3 5.3 37.0 21.4 7.2 5.2 6.0 9.1 6.0 23.4 21.8 5.6 6.4 17.8 5.0 26.5 68.5 96.5 32.8 80.2 26.1 12.1 18.9 32.5 71.6 18.0 14.0 25.2 44.0 26.9 78.3 16.2 32.2 41.5 9.6 9.3 9.4 13.2 9.2 9.1 9.4 9.2 8.9 8.6 9.7 9.1 5.3 3.2 5.1 6.2 12.4 1.5 4.4 16.6 1.2 13.7 8.7 5.8 0.6 15.7 9.6 3.7 0.0 37.9 16.0 26.4 1.9 19.1 69.1 7.0 5.7 8.5 22.8 34.1 5.5 27.4 38.9 10.1 8.2 10.8 5.7 11.7 15.0 7.5 56.9 8.4 4.6 20.4 20.3 33.9 8.3 10.7 11.5 26.2 3.6 2.8 25.2 11.7 30.9 6.0 3.7 15.5 28.7 11.3 21.1 6.0 33.9 8.7 7.7 14.6 0.0 2.5 4.2 30.6 10.9 7.5 1.4 51.9 15.0 114.6 18.3 4.9 TRAF7 "DKFZp586I021, MGC7807, RFWD1, RNF119" ENSG00000131653 "TNF receptor associated factor 7" Q6Q0C0 16 2155698-2178129 "Cancer-related genes, Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Apoptosis, Transcription, Transcription regulation, Ubl conjugation pathway" Transferase "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041229 Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 7: Monocytes - Unknown function" "Cluster 37: Intestine - Unknown function" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 7: Non-specific - Mitochondria" Vesicles "Plasma membrane" "HPA041229: AB_10794194" "unprognostic (1.94e-1)" "unprognostic (5.97e-2)" "unprognostic (1.13e-1)" "unprognostic (4.23e-2)" "unprognostic (1.09e-1)" "unprognostic (1.03e-1)" "unprognostic (1.65e-2)" "unprognostic (2.77e-3)" "unprognostic (7.08e-2)" "unprognostic (3.52e-2)" "unprognostic (1.52e-2)" "unprognostic (1.08e-1)" "unprognostic (9.23e-2)" "unprognostic (6.07e-2)" "unprognostic (2.99e-2)" "unprognostic (2.43e-1)" "unprognostic (8.48e-2)" 29.1 29.4 16.5 24.4 15.1 35.0 28.2 18.2 23.0 32.1 17.0 38.0 40.0 31.2 11.6 54.6 30.4 22.2 21.3 17.9 14.6 28.1 51.5 33.2 22.9 17.8 15.3 23.5 37.4 14.6 32.1 20.6 14.8 27.0 17.4 8.5 34.7 16.5 30.4 47.7 35.2 18.8 14.2 34.5 35.6 14.8 17.7 19.1 25.6 9.9 18.6 34.5 34.8 14.3 57.7 72.2 40.3 72.5 40.8 76.5 47.4 43.4 53.9 49.9 44.6 88.2 72.1 36.6 50.2 55.4 31.8 65.9 38.1 76.8 18.8 58.3 48.8 52.4 98.5 68.3 53.8 56.3 72.7 76.2 62.8 48.1 62.6 41.0 97.4 70.6 57.1 47.9 48.2 131.1 58.3 65.2 79.7 78.7 34.8 107.4 66.7 74.2 40.2 30.4 80.9 67.2 36.3 68.5 48.6 20.9 78.1 68.2 74.3 60.2 83.9 56.7 48.2 69.2 55.0 48.4 34.4 35.9 47.8 4.0 9.1 7.3 4.5 12.4 4.3 5.5 4.4 4.7 11.2 3.9 3.1 3.8 6.2 2.9 8.9 5.3 6.5 5.3 16.5 15.1 18.2 23.0 17.9 14.6 17.8 15.3 14.8 14.2 17.7 14.3 18.9 0.0 9.2 12.4 18.2 28.8 21.1 34.2 22.8 15.9 31.6 27.9 4.9 21.5 20.8 14.7 6.2 23.5 17.4 56.4 17.6 39.0 5.0 23.6 34.6 26.5 34.0 33.6 8.9 59.0 36.3 19.0 38.7 27.9 9.5 22.1 26.0 32.3 42.2 37.0 8.2 38.7 34.6 41.8 21.3 13.1 24.8 26.8 10.6 8.4 33.9 12.6 6.2 6.6 4.9 53.0 43.6 22.2 24.0 33.8 80.0 29.2 19.7 10.9 6.6 11.9 18.3 8.5 25.3 50.7 32.5 26.7 16.0 29.0 42.5 38.5 TRAIP "RNF206, TRIP" ENSG00000183763 "TRAF interacting protein" Q9BWF2 3 49828601-49856574 "Disease related genes, Enzymes, Human disease related genes, Potential drug targets, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Disease variant, Dwarfism, Mental retardation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Extravillous trophoblasts: 8.2;Spermatocytes: 15.6;Spermatogonia: 9.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in many" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Region enhanced" "Detected in many" "basal ganglia: 10.8" "HPA036261, HPA036262" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 37: B-cells - Transcription" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "HPA036261: AB_10673348, HPA036262: AB_2675029" "unprognostic (5.30e-3)" "unprognostic (9.41e-2)" "unprognostic (1.48e-1)" "unprognostic (6.50e-3)" "unprognostic (1.88e-1)" "unprognostic (7.68e-3)" "prognostic unfavorable (8.77e-5)" "unprognostic (4.61e-2)" "unprognostic (1.52e-2)" "unprognostic (8.61e-2)" "unprognostic (1.24e-2)" "unprognostic (7.97e-2)" "unprognostic (9.01e-5)" "unprognostic (5.84e-2)" "unprognostic (4.24e-1)" "unprognostic (1.78e-1)" "unprognostic (1.24e-1)" 1.5 1.0 1.6 1.8 2.5 6.8 1.9 0.7 1.8 2.0 0.4 2.3 1.5 1.7 1.4 2.9 1.8 1.0 0.9 1.6 0.9 0.8 0.8 0.9 4.6 0.6 0.6 2.1 1.0 0.8 1.2 1.6 0.7 1.4 2.9 2.3 1.2 0.9 2.0 4.2 2.0 2.1 0.6 1.9 1.2 7.9 1.3 5.3 1.4 1.2 4.4 1.3 1.9 0.9 10.4 12.4 17.4 17.6 1.6 2.4 14.4 12.4 5.8 25.3 24.0 15.2 11.6 25.5 8.5 7.1 17.7 13.4 18.5 14.0 18.8 14.7 12.2 19.2 16.3 13.6 0.7 15.8 15.4 1.6 2.0 20.4 10.7 3.0 6.7 22.3 14.0 17.8 11.4 15.1 26.5 20.1 14.0 12.3 20.3 14.4 11.7 14.8 4.6 14.2 8.4 14.4 13.6 11.3 8.8 12.4 10.2 22.4 5.2 16.1 19.0 22.5 24.4 13.0 33.7 27.3 8.1 21.2 14.6 0.0 0.6 0.3 0.9 0.3 0.9 2.9 0.5 2.1 0.6 1.5 0.7 1.1 0.1 1.2 1.3 0.7 0.3 0.6 1.6 2.5 0.7 1.8 1.6 0.9 0.6 0.6 0.7 0.6 1.3 0.9 0.6 3.2 0.6 1.0 1.8 1.1 0.6 1.5 2.2 2.8 1.2 1.4 2.6 0.0 0.3 3.7 0.0 4.2 1.2 1.8 0.0 2.0 4.3 0.6 0.9 0.8 0.0 3.8 1.4 1.0 8.2 2.0 1.5 0.9 0.0 5.7 1.1 0.7 3.5 0.0 0.9 2.0 0.0 0.8 0.4 4.8 2.5 0.7 1.8 1.0 1.8 1.7 0.0 0.5 0.6 1.1 0.3 1.2 4.3 0.8 0.9 0.3 0.5 3.3 0.0 1.4 1.7 15.6 9.1 2.3 0.3 1.0 1.2 1.2 4.6 0.2 TRAPPC13 "C5orf44, FLJ13611, MGC48585" ENSG00000113597 "Trafficking protein particle complex 13" A5PLN9 5 65625004-65666233 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Oligodendrocytes: 66.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA037777 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA037777: AB_10672464" "unprognostic (3.66e-2)" "unprognostic (3.27e-1)" "unprognostic (1.54e-2)" "unprognostic (7.22e-2)" "unprognostic (4.79e-2)" "unprognostic (1.16e-2)" "unprognostic (2.55e-2)" "unprognostic (2.49e-2)" "unprognostic (5.70e-2)" "unprognostic (5.75e-2)" "unprognostic (3.49e-2)" "unprognostic (1.92e-1)" "prognostic favorable (8.66e-4)" "unprognostic (2.89e-1)" "unprognostic (2.58e-2)" "unprognostic (2.53e-2)" "unprognostic (6.25e-2)" 10.0 11.5 7.8 8.9 8.4 8.0 12.8 9.1 9.9 10.6 7.0 10.8 9.3 10.8 9.1 12.4 8.9 9.3 16.8 8.3 9.4 20.0 14.7 10.5 10.8 8.7 8.8 7.6 7.3 22.7 8.8 10.4 8.8 18.7 13.3 16.6 9.1 10.9 13.4 5.8 9.1 12.9 9.1 9.9 10.0 10.6 8.7 16.6 17.3 16.8 10.8 12.1 7.0 10.4 20.7 13.6 21.0 38.2 15.8 20.2 20.7 23.8 21.2 29.1 31.2 11.8 28.7 21.3 25.5 19.5 31.0 18.8 24.0 25.0 33.9 14.6 17.8 13.4 15.3 11.1 21.7 16.6 19.3 14.5 19.2 22.7 28.8 17.5 25.8 30.0 16.2 19.1 26.3 21.9 27.3 6.4 9.5 11.9 7.4 23.7 26.9 24.0 20.8 23.2 25.4 19.2 29.3 17.4 22.2 11.6 25.7 20.8 17.8 10.2 14.0 22.6 24.4 12.6 26.3 34.0 21.3 28.9 19.8 17.6 8.3 3.6 8.4 9.3 11.0 5.8 8.1 7.0 9.0 4.7 7.9 7.9 3.1 8.9 13.4 6.7 9.3 9.1 7.8 8.4 9.1 9.9 8.3 9.4 8.7 8.8 8.8 9.1 8.7 10.4 10.4 19.2 10.5 27.1 7.4 5.7 6.8 17.3 6.2 13.3 8.5 5.5 7.1 12.8 13.1 7.3 10.4 12.1 13.0 7.6 15.6 12.9 24.6 7.9 7.6 11.9 15.5 12.0 54.7 10.8 9.6 9.1 11.2 7.6 3.8 9.8 8.2 11.2 12.4 13.5 44.2 8.9 26.4 13.9 7.7 10.2 7.5 9.6 7.2 28.1 11.1 14.8 11.3 46.3 66.5 10.3 6.3 13.2 8.9 11.8 11.0 25.2 13.4 16.2 6.6 8.7 8.3 16.4 8.6 9.1 6.8 15.2 12.0 10.2 8.7 11.9 TRDN TRISK ENSG00000186439 Triadin Q13061 6 123216339-123637093 "Disease related genes, Human disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "heart muscle: 421.6;skeletal muscle: 1944.1;tongue: 1018.2" "Group enriched" "Detected in some" 11 "Cardiomyocytes: 1145.1;Muller glia cells: 765.7;Skeletal myocytes: 398.6" "Group enriched" "Detected in some" 5 "head and neck cancer: 2.2;prostate cancer: 0.6" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in single" "MCF7: 1.9" "Region enriched" "Detected in some" 10 "olfactory bulb: 11.0" "Region enriched" "Detected in some" 23 "olfactory bulb: 28.9" "HPA038226, HPA058226" Enhanced Approved "Plasma membrane,Cytosol" NA NA "Cluster 41: Basophils - Cellular respiration" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 40: Non-specific - Basic cellular processes" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane, Cytosol" "HPA038226: AB_10795574, HPA058226: AB_2683643" "unprognostic (1.05e-2)" "unprognostic (1.99e-1)" "unprognostic (9.20e-2)" "unprognostic (3.06e-3)" "unprognostic (2.40e-1)" "unprognostic (2.38e-1)" "unprognostic (2.42e-1)" "unprognostic (8.42e-2)" "unprognostic (8.71e-2)" "unprognostic (9.93e-3)" "unprognostic (2.12e-1)" "unprognostic (2.55e-2)" "unprognostic (3.97e-2)" 16.3 2.6 4.2 0.0 3.7 0.0 2.0 4.0 5.8 0.7 3.1 0.4 0.0 1.7 10.4 18.5 12.5 0.2 421.6 3.0 12.5 0.4 0.1 0.4 0.1 6.7 7.0 1.3 0.1 0.0 15.3 0.2 7.9 17.0 0.3 83.5 13.1 0.9 1944.1 0.6 0.2 1.0 9.2 0.1 0.1 5.1 10.2 0.3 0.3 1018.2 0.1 0.0 0.6 6.3 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.0 1.9 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.8 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.2 0.0 0.0 0.0 0.0 0.8 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.2 3.7 4.0 5.8 3.0 12.5 6.7 7.0 7.9 9.2 10.2 6.3 0.3 0.0 0.0 4.2 0.0 0.0 0.5 0.0 0.0 7.9 0.0 0.3 1145.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.9 0.0 68.0 0.0 0.0 6.0 0.0 0.0 1.1 0.0 0.0 38.4 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 1.6 0.0 0.0 0.0 0.4 35.5 13.1 0.5 1.8 0.0 0.0 765.7 0.0 3.0 3.2 0.0 0.0 11.3 0.0 0.0 0.0 0.2 0.0 21.8 0.0 398.6 7.1 1.3 0.9 0.0 0.0 0.0 0.3 0.0 0.0 0.0 TRIB1 "C8FW, GIG2, TRB1" ENSG00000173334 "Tribbles pseudokinase 1" Q96RU8 8 125430358-125438403 "Enzymes, Predicted intracellular proteins" "Protein kinase inhibitor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 365.5" "Cell type enhanced" "Detected in many" "Basal prostatic cells: 242.7;Distal enterocytes: 281.6;Endometrial stromal cells: 240.1;Plasma cells: 283.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Group enriched" "Detected in some" 4 "eosinophil: 9.9;neutrophil: 4.7;non-classical monocyte: 3.5;T-reg: 2.8" "Group enriched" "Detected in many" 12 "granulocytes: 9.9;monocytes: 3.5;T-cells: 2.8" "Cell line enhanced" "Detected in many" "HEL: 193.9;U-266/70: 114.2;U-266/84: 123.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA063982 Approved "Plasma membrane,Cytosol" NA NA "Cluster 52: Eosinophils - Transcription" "Cluster 67: Neutrophils - Humoral immune response" "Cluster 36: HEL - Hemostasis" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane, Cytosol" "HPA063982: AB_2685165" "unprognostic (1.90e-3)" "unprognostic (1.45e-1)" "unprognostic (8.80e-3)" "unprognostic (1.34e-2)" "unprognostic (3.56e-1)" "unprognostic (2.32e-1)" "unprognostic (2.00e-1)" "unprognostic (4.57e-2)" "unprognostic (4.12e-2)" "unprognostic (1.62e-2)" "unprognostic (6.81e-3)" "unprognostic (9.36e-2)" "unprognostic (2.97e-3)" "unprognostic (1.94e-1)" "unprognostic (1.04e-2)" "unprognostic (5.55e-2)" "unprognostic (2.08e-2)" 82.5 25.5 7.5 40.9 9.0 365.5 28.0 12.1 16.2 35.9 7.0 45.1 20.4 25.5 13.6 33.5 15.7 80.2 18.3 8.2 10.1 23.9 139.6 53.7 17.2 9.0 8.4 4.1 43.0 78.9 12.0 28.9 8.7 45.4 51.9 16.3 19.2 7.1 44.0 20.4 32.0 43.2 7.5 22.3 38.0 6.9 11.9 36.0 107.5 19.2 18.0 99.1 5.4 7.6 14.7 16.4 2.2 4.6 4.6 8.8 25.4 9.4 13.2 6.8 2.3 22.1 18.9 26.5 8.5 6.9 40.6 11.0 7.0 9.1 5.8 11.8 34.3 193.9 7.3 43.6 11.6 98.3 17.0 8.5 13.5 27.8 62.8 33.0 20.0 0.3 17.5 81.6 0.9 15.8 9.2 15.3 15.8 35.1 31.6 18.5 3.3 29.2 54.6 55.1 13.7 5.0 22.9 24.6 93.1 14.0 6.4 4.6 10.4 7.3 9.5 7.3 11.7 114.2 123.2 36.6 13.1 0.7 17.7 0.0 0.7 9.9 0.0 1.1 0.0 0.2 0.1 0.0 0.4 0.0 0.0 0.0 4.7 0.0 3.5 0.3 2.8 0.1 7.5 9.0 12.1 16.2 8.2 10.1 9.0 8.4 8.7 7.5 11.9 7.6 69.6 134.6 168.5 13.7 19.8 100.1 242.7 68.6 77.4 25.5 100.8 71.9 16.6 31.5 67.9 16.5 0.0 12.3 2.8 281.6 11.7 45.3 0.4 96.6 240.1 62.0 112.0 5.3 2.1 24.7 19.1 54.6 58.6 222.5 29.9 0.5 8.2 131.7 35.3 21.9 0.7 129.6 32.6 72.0 59.7 1.7 0.3 85.9 56.9 4.7 27.5 20.1 0.0 4.5 0.2 45.5 130.9 0.4 283.6 139.0 117.4 24.9 39.7 3.8 0.0 36.6 45.1 0.3 2.2 88.2 64.2 30.6 14.8 1.5 106.9 128.7 TRIM16 EBBP ENSG00000221926 "Tripartite motif containing 16" O95361 17 15627960-15684311 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 145.9" "Cell type enhanced" "Detected in many" "Pancreatic endocrine cells: 153.4;Squamous epithelial cells: 95.5;Urothelial cells: 111.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "T-reg: 45.1" "Lineage enriched" "Detected in many" 12 "T-cells: 45.1" "Cell line enhanced" "Detected in all" "A549: 283.8;HaCaT: 229.0;HeLa: 203.8;OE19: 364.2" "Low region specificity" "Detected in many" "Low region specificity" "Detected in many" "HPA023623, HPA066431" Uncertain Supported "Plasma membrane,Cytosol" NA NA 19000 "Cluster 4: T-regs - Cell cycle regulation" "Cluster 84: Esophagus - Epithelial cell function" "Cluster 21: OE19 - Mitochondria" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "HPA023623: AB_1858273, HPA066431: AB_2685668" "unprognostic (2.14e-1)" "unprognostic (1.95e-1)" "unprognostic (9.61e-2)" "unprognostic (1.31e-2)" "unprognostic (6.19e-2)" "unprognostic (1.21e-1)" "prognostic unfavorable (3.94e-4)" "unprognostic (1.94e-3)" "unprognostic (3.75e-2)" "unprognostic (4.65e-1)" "unprognostic (3.31e-3)" "unprognostic (1.70e-1)" "unprognostic (2.16e-3)" "unprognostic (2.08e-1)" "unprognostic (8.48e-2)" "unprognostic (9.21e-3)" "prognostic unfavorable (6.71e-4)" 18.3 32.7 14.1 7.8 16.2 17.4 13.4 17.7 21.5 44.9 10.3 14.1 22.8 6.1 4.9 145.9 8.8 16.3 23.1 13.5 15.8 8.5 5.9 14.5 9.7 16.9 16.0 7.3 6.0 3.6 4.4 34.5 17.2 10.2 11.2 3.6 38.0 11.7 28.1 44.9 12.5 9.0 15.8 6.0 31.7 12.7 17.2 10.1 18.7 27.2 37.3 35.7 70.2 22.1 91.5 283.8 8.6 19.4 40.4 46.1 9.6 14.8 51.9 17.9 25.0 17.2 115.6 9.8 54.7 64.7 106.9 229.0 25.6 65.7 12.0 120.0 16.4 4.5 203.8 9.5 67.1 5.4 9.6 25.7 40.9 39.3 22.3 49.6 38.8 11.4 5.7 45.8 49.2 32.2 20.2 11.7 13.1 364.2 17.0 8.7 71.8 6.9 92.4 116.0 6.4 17.7 64.7 72.2 22.1 49.7 10.9 12.6 61.0 22.5 26.3 10.9 51.3 11.1 12.9 1.0 34.6 12.6 58.3 0.4 3.8 1.0 1.2 1.1 0.8 0.5 4.9 1.5 2.6 0.6 1.3 2.6 0.6 0.9 0.5 0.4 45.1 2.3 14.1 16.2 17.7 21.5 13.5 15.8 16.9 16.0 17.2 15.8 17.2 22.1 34.9 38.5 2.6 14.0 5.3 30.8 59.0 55.6 10.2 7.2 11.8 5.7 12.5 10.0 73.5 11.0 18.8 13.6 2.8 9.9 0.0 49.1 1.1 16.5 9.9 28.7 4.2 9.0 9.6 17.3 8.4 9.6 34.7 25.7 4.5 12.4 3.6 3.2 4.0 3.3 14.0 21.7 28.5 2.9 8.6 3.9 7.2 2.9 7.2 11.2 13.0 6.6 4.1 18.6 19.2 153.4 26.9 4.5 3.7 29.5 4.3 6.2 33.5 8.4 6.6 5.8 14.0 10.3 12.1 95.5 77.6 4.7 5.9 60.9 18.4 111.9 TRIM4 RNF87 ENSG00000146833 "Tripartite motif containing 4" Q9C037 7 99876958-99919531 "Enzymes, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA019356, HPA029461" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 30: Epithelial cell lines - Translation" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "HPA019356: AB_1856376, HPA029461: AB_10600834" "unprognostic (1.88e-1)" "unprognostic (2.97e-2)" "unprognostic (3.37e-1)" "unprognostic (3.46e-2)" "unprognostic (1.80e-2)" "unprognostic (7.06e-2)" "unprognostic (1.22e-1)" "unprognostic (5.42e-2)" "unprognostic (3.85e-2)" "unprognostic (2.67e-3)" "unprognostic (2.48e-2)" "unprognostic (1.60e-1)" "prognostic favorable (7.36e-6)" "unprognostic (1.00e-1)" "unprognostic (2.38e-1)" "unprognostic (7.46e-2)" "unprognostic (5.65e-2)" 18.7 21.5 11.0 17.1 11.5 9.3 26.8 15.5 12.6 18.9 15.4 17.3 17.5 23.7 19.8 15.3 22.9 15.2 10.0 10.5 11.9 20.6 22.9 18.5 22.4 11.2 11.9 41.3 23.8 25.5 16.2 19.9 10.9 23.0 19.2 21.5 19.0 20.2 7.5 21.8 18.6 19.9 10.7 21.5 20.1 16.0 12.0 20.9 24.5 11.8 23.8 17.3 17.3 13.3 20.8 26.2 14.4 12.0 37.0 34.6 6.3 34.6 41.3 28.0 32.4 13.1 20.1 30.3 0.1 28.8 24.2 24.3 19.0 21.2 28.4 31.2 1.4 25.3 13.1 20.8 52.4 35.9 29.4 36.9 44.3 21.6 54.7 37.8 24.6 14.9 37.1 45.3 23.9 26.4 26.8 32.2 10.9 31.0 21.0 15.0 20.6 34.6 31.6 26.4 16.8 11.9 26.4 39.4 42.3 20.7 18.2 20.2 30.6 30.7 27.6 59.5 33.6 37.7 44.4 24.0 20.1 39.7 41.7 38.2 28.4 23.6 28.5 28.6 32.8 26.2 29.4 32.6 24.9 25.3 40.7 30.4 11.7 22.3 26.1 18.5 32.8 28.0 11.0 11.5 15.5 12.6 10.5 11.9 11.2 11.9 10.9 10.7 12.0 13.3 17.8 25.6 20.1 19.2 32.3 25.1 24.8 17.7 25.0 21.6 21.8 18.0 6.1 18.6 14.2 22.0 18.8 16.4 28.1 10.1 9.8 15.9 7.4 12.5 25.4 18.8 9.0 16.8 18.3 12.8 6.7 20.1 19.4 11.4 27.3 19.0 22.5 20.4 14.3 6.7 20.7 10.4 16.2 21.4 14.8 13.1 31.1 21.2 23.2 12.2 27.0 35.9 32.0 23.1 22.5 14.9 10.4 27.4 20.1 26.6 17.8 19.0 16.5 22.1 0.0 21.8 20.4 22.4 9.4 18.0 23.0 16.3 29.8 52.5 13.5 23.6 TRIM44 "DIPB, MC7" ENSG00000166326 "Tripartite motif containing 44" Q96DX7 11 35662775-35818007 "Disease related genes, Human disease related genes, Predicted intracellular proteins" "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA049053, HPA057633" Approved Approved "Vesicles,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 9: Photoreceptor cells - Phototransduction" Vesicles "Plasma membrane" "HPA049053: AB_2680613, HPA057633: AB_2683484" "unprognostic (2.73e-1)" "unprognostic (2.74e-1)" "unprognostic (1.37e-1)" "unprognostic (5.53e-2)" "unprognostic (3.91e-2)" "unprognostic (1.81e-1)" "prognostic unfavorable (5.24e-5)" "unprognostic (9.06e-2)" "unprognostic (5.29e-2)" "unprognostic (2.67e-1)" "unprognostic (1.02e-1)" "unprognostic (8.57e-2)" "unprognostic (1.49e-3)" "unprognostic (2.15e-2)" "unprognostic (1.59e-1)" "unprognostic (1.52e-1)" "unprognostic (3.00e-1)" 12.6 10.7 16.9 12.3 16.4 6.0 11.1 18.5 21.9 10.9 8.3 13.5 10.6 10.9 10.2 9.1 11.1 11.6 11.6 16.6 17.0 18.0 14.4 11.9 12.8 16.0 16.7 10.3 15.5 11.1 7.9 13.3 16.1 10.4 11.1 27.0 9.4 11.4 11.5 8.3 12.0 12.2 17.8 14.1 11.3 6.7 17.3 12.1 14.9 9.8 13.2 11.1 8.6 19.0 20.1 16.9 26.4 12.3 19.6 29.6 0.1 18.5 21.9 22.7 20.6 19.7 13.3 26.7 17.1 24.3 25.7 15.4 9.1 21.1 25.4 17.6 17.4 28.7 23.0 11.4 26.0 22.7 23.7 22.4 23.2 13.3 36.0 25.1 24.3 9.2 45.4 9.3 24.1 12.1 24.1 11.1 14.9 4.2 14.5 16.6 68.4 14.5 21.0 26.9 18.1 15.5 27.7 19.6 21.0 14.3 29.5 19.0 27.4 28.9 23.8 16.6 21.2 15.7 15.0 0.1 23.9 23.7 22.2 0.2 0.9 0.3 0.9 1.2 0.8 1.1 0.9 0.9 0.8 1.5 1.1 1.2 0.0 1.2 1.5 1.8 0.3 0.5 16.9 16.4 18.5 21.9 16.6 17.0 16.0 16.7 16.1 17.8 17.3 19.0 67.5 60.9 72.6 78.4 68.5 26.8 57.9 19.8 74.0 221.5 45.3 38.2 58.9 55.8 45.6 25.8 204.3 55.4 72.1 70.3 33.2 62.8 18.8 78.0 74.0 62.4 51.4 39.3 151.7 71.1 25.9 49.4 74.9 54.4 58.9 107.1 49.2 53.3 42.7 84.1 134.5 57.6 16.2 65.7 37.8 13.4 36.1 70.3 19.6 84.3 76.9 72.2 72.1 121.7 171.0 53.3 50.4 37.2 59.6 90.3 50.9 75.6 48.4 173.4 98.6 71.9 52.1 88.2 81.5 46.1 26.7 52.1 47.0 58.5 54.5 59.9 TRIM54 "MURF, MURF-3, RNF30" ENSG00000138100 "Tripartite motif containing 54" Q9BYV2 2 27282429-27307439 "Predicted intracellular proteins" Differentiation "Developmental protein" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 13 "heart muscle: 213.2;skeletal muscle: 580.7;tongue: 177.3" "Cell type enhanced" "Detected in some" "Cardiomyocytes: 81.7;Ductal cells: 35.5;Exocrine glandular cells: 42.5;Pancreatic endocrine cells: 46.5;Skeletal myocytes: 17.9;Smooth muscle cells: 16.8" "Low cancer specificity" "Detected in many" "Region enhanced" "Detected in many" "cerebral cortex: 5.1" "Immune cell enriched" "Detected in single" 17 "NK-cell: 3.6" "Lineage enriched" "Detected in single" 17 "NK-cells: 3.6" "Group enriched" "Detected in some" 8 "HAP1: 7.3;NTERA-2: 15.6" "Region enhanced" "Detected in some" "amygdala: 3.1" HPA019690 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 48: NK-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 5: NTERA-2 - Transcription" "Cluster 16: Pancreatic endocrine cells - Mixed function" "Plasma membrane, Cytosol" "HPA019690: AB_1858306" "unprognostic (6.98e-3)" "unprognostic (4.56e-3)" "unprognostic (3.22e-2)" "unprognostic (2.24e-2)" "unprognostic (1.58e-3)" "unprognostic (7.49e-2)" "unprognostic (1.25e-7)" "unprognostic (3.88e-3)" "unprognostic (2.29e-1)" "unprognostic (2.95e-1)" "unprognostic (2.56e-3)" "unprognostic (6.91e-2)" "prognostic unfavorable (6.46e-4)" "unprognostic (2.41e-2)" "unprognostic (3.19e-1)" "unprognostic (1.15e-1)" "unprognostic (6.92e-2)" 0.4 9.3 1.5 0.0 0.9 0.0 0.3 0.9 5.1 0.9 0.1 0.3 4.3 0.8 24.5 5.0 0.8 0.2 213.2 2.3 0.0 1.7 0.1 0.2 0.2 0.6 0.3 0.5 0.5 0.0 0.1 0.0 0.3 3.4 0.0 0.0 9.5 0.1 580.7 0.9 2.1 0.0 0.3 0.9 0.1 22.3 0.1 0.1 0.5 177.3 0.0 0.1 0.5 1.2 0.4 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.1 0.0 7.3 0.0 0.0 0.0 0.2 0.0 1.4 1.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.2 15.6 0.0 0.0 0.5 0.6 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.1 0.1 0.1 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.2 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 3.6 0.0 0.0 0.0 0.0 1.5 0.9 0.9 5.1 2.3 0.0 0.6 0.3 0.3 0.3 0.1 1.2 0.0 0.0 0.0 0.7 0.2 0.0 0.2 0.3 0.0 0.0 0.5 0.4 81.7 10.0 0.1 3.7 0.0 0.0 0.3 2.3 0.0 35.5 1.5 0.1 0.0 0.8 0.0 2.7 11.3 42.5 0.0 2.2 0.0 0.2 4.5 0.0 0.4 0.0 0.1 0.0 0.8 1.8 0.0 0.0 0.0 4.7 0.0 0.1 0.0 1.0 0.0 0.0 0.0 0.0 0.3 46.5 1.9 0.7 0.0 0.2 2.4 3.1 0.2 0.0 0.0 17.9 16.8 6.8 2.4 0.0 0.0 0.0 0.3 0.2 6.4 0.3 TRIML2 "FLJ25801, SPRYD6" ENSG00000179046 "Tripartite motif family like 2" Q8N7C3 4 188091273-188109603 "Enzymes, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "placenta: 4.1;testis: 2.6" "Group enriched" "Detected in some" 6 "Cytotrophoblasts: 16.5;Early spermatids: 17.3;Extravillous trophoblasts: 6.7;Late spermatids: 5.2;Spermatocytes: 6.4;Spermatogonia: 6.4;Syncytiotrophoblasts: 8.9" "Cancer enriched" "Detected in some" 33 "testis cancer: 24.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 4 "SuSa: 145.3" "Not detected" "Not detected" "Not detected" "Not detected" HPA043838 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 12: NES - Nervous system development" "Cluster 47: Cytotrophoblasts - Unknown function" "Plasma membrane, Cytosol" "HPA043838: AB_10963835" "unprognostic (3.32e-1)" "unprognostic (1.99e-1)" "unprognostic (1.30e-1)" "unprognostic (9.82e-2)" "unprognostic (1.21e-5)" "unprognostic (3.06e-2)" "unprognostic (1.65e-3)" "unprognostic (2.65e-1)" "unprognostic (0.00e+0)" "unprognostic (2.26e-2)" "unprognostic (1.20e-1)" "unprognostic (1.28e-3)" 0.0 0.0 0.1 0.0 0.2 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.6 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 3.7 33.8 0.0 0.0 0.0 0.1 18.3 0.2 1.4 0.0 0.0 0.2 0.5 0.0 0.0 0.0 7.5 0.9 6.4 0.1 0.0 2.4 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 21.4 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 34.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.1 0.0 145.3 0.0 0.0 0.2 0.1 7.6 0.0 0.0 0.0 0.0 0.0 2.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.3 0.0 0.0 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 0.0 16.5 0.0 0.0 0.0 0.0 17.3 0.0 0.0 0.1 0.0 0.0 1.6 0.0 6.7 0.2 0.0 0.0 0.0 0.0 0.0 0.0 1.4 0.0 0.3 0.0 0.0 0.0 0.5 5.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.1 6.4 6.4 0.0 0.0 8.9 0.1 0.0 0.0 0.3 TRMT10B "bA3J10.9, FLJ31455, RG9MTD3" ENSG00000165275 "TRNA methyltransferase 10B" Q6PF06 9 37753803-37778972 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA021800 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA021800: AB_1856214" "unprognostic (1.00e-2)" "unprognostic (1.78e-1)" "unprognostic (3.35e-2)" "unprognostic (3.89e-2)" "unprognostic (2.42e-2)" "unprognostic (7.68e-2)" "unprognostic (7.78e-2)" "prognostic favorable (3.91e-4)" "unprognostic (5.49e-3)" "unprognostic (1.71e-2)" "prognostic favorable (5.34e-4)" "unprognostic (1.40e-1)" "unprognostic (6.62e-2)" "unprognostic (1.76e-2)" "unprognostic (1.68e-1)" "unprognostic (9.58e-2)" "unprognostic (2.33e-3)" 5.6 6.9 7.3 5.7 8.1 6.0 6.2 10.7 8.0 8.3 5.8 8.3 4.4 7.1 4.4 5.5 7.6 4.1 4.9 6.8 7.3 6.9 6.4 4.9 7.4 7.9 7.6 9.5 7.9 3.9 6.7 3.8 7.1 8.3 3.5 7.3 6.1 4.2 4.4 10.7 7.1 4.0 6.6 8.1 6.7 3.4 7.6 4.0 7.6 2.1 4.2 7.6 7.1 9.8 4.7 5.6 7.0 6.2 4.2 3.3 3.1 4.4 3.3 4.5 3.9 3.3 4.1 8.7 3.3 3.4 2.7 5.3 3.3 5.5 4.1 3.7 5.6 7.8 14.8 3.5 7.6 8.0 5.2 3.8 5.5 4.3 7.4 5.3 4.7 10.4 6.2 3.6 3.4 3.3 8.1 6.2 6.2 5.0 6.7 8.1 2.4 4.6 4.3 4.2 9.4 9.0 3.7 4.7 4.1 4.4 5.0 5.7 4.8 3.6 5.1 5.9 4.0 4.2 6.1 6.9 2.1 6.1 7.3 3.4 2.7 1.5 3.1 2.4 3.8 3.3 2.8 3.1 1.2 4.3 3.3 3.0 2.8 2.4 1.7 2.3 1.9 1.5 7.3 8.1 10.7 8.0 6.8 7.3 7.9 7.6 7.1 6.6 7.6 9.8 13.2 3.2 8.9 30.3 20.3 7.4 11.4 8.9 15.9 16.2 13.5 16.5 7.4 14.3 8.4 3.7 6.2 16.1 11.0 7.9 11.7 11.3 2.1 7.1 14.1 12.8 13.8 13.7 25.4 12.5 8.6 14.0 13.7 9.1 14.5 17.3 13.6 8.1 8.2 16.8 27.5 14.0 8.2 10.4 9.5 0.9 14.6 12.2 10.6 19.7 15.5 15.9 25.7 37.2 45.7 10.0 6.7 23.7 9.1 14.2 11.4 9.0 7.8 13.5 26.3 13.0 11.1 4.2 5.3 9.7 7.5 12.2 16.4 12.3 10.9 9.4 TRPM4 FLJ20041 ENSG00000130529 "Transient receptor potential cation channel subfamily M member 4" Q8TD43 19 49157741-49211836 "Disease related genes, Human disease related genes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters, Voltage-gated ion channels" "Adaptive immunity, Immunity, Ion transport, Transport" "Calmodulin-binding, Ion channel" "Disease variant, Palmoplantar keratoderma" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Distal enterocytes: 179.2;Hepatocytes: 81.7;Intestinal goblet cells: 114.8;Paneth cells: 77.1;Undifferentiated cells: 88.9" "Cancer enriched" "Detected in all" 4 "prostate cancer: 85.3" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Group enriched" "Detected in many" 7 "dendritic cells: 3.3;granulocytes: 2.8;monocytes: 4.3" "Cell line enhanced" "Detected in many" "OE19: 32.7;RT4: 60.8;SK-BR-3: 38.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in many" HPA041169 Enhanced Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 41: Intestine & Liver - Lipid metabolism" "Cluster 15: RT4 - Unknown function" "Cluster 53: Intestinal epithelial cells - Unknown function" "Nucleoplasm, Plasma membrane" "HPA041169: AB_2677343" "unprognostic (8.20e-3)" "unprognostic (1.41e-1)" "unprognostic (7.86e-2)" "prognostic favorable (2.88e-7)" "unprognostic (1.62e-2)" "unprognostic (9.78e-2)" "unprognostic (1.77e-2)" "unprognostic (2.90e-1)" "unprognostic (3.33e-2)" "unprognostic (3.38e-2)" "unprognostic (2.94e-2)" "unprognostic (2.79e-1)" "prognostic favorable (2.53e-7)" "unprognostic (8.46e-3)" "unprognostic (2.16e-1)" "unprognostic (5.70e-2)" "unprognostic (1.00e-2)" 10.8 6.1 5.8 6.1 5.4 4.6 13.5 8.5 7.0 11.5 4.8 46.1 25.3 9.9 2.5 13.1 9.2 7.4 23.0 5.9 4.5 22.8 15.4 16.0 1.8 6.2 7.4 3.3 10.1 3.7 5.6 5.3 6.9 35.7 12.9 1.3 27.3 6.2 14.0 26.6 22.9 3.4 4.2 5.5 20.6 5.4 6.6 1.0 17.3 5.3 1.9 13.7 14.4 5.1 11.9 9.0 2.1 9.5 7.7 6.6 6.6 10.0 6.0 2.7 3.7 6.1 18.7 0.4 2.7 6.8 3.6 15.7 1.3 3.0 1.0 0.2 3.4 1.9 4.0 3.7 6.6 0.3 11.7 9.3 13.6 5.3 2.6 3.3 4.6 1.0 4.9 2.1 6.9 17.4 0.8 0.9 1.0 32.7 13.3 4.1 2.0 0.6 4.6 60.8 0.8 2.2 4.1 38.6 2.2 0.7 22.6 3.7 11.8 14.4 7.8 7.9 0.2 3.9 4.3 0.4 7.9 7.4 5.3 2.2 4.3 0.7 0.3 2.5 0.2 0.5 0.2 0.2 3.3 0.5 0.3 0.3 2.8 0.5 1.0 3.1 0.2 1.4 5.8 5.4 8.5 7.0 5.9 4.5 6.2 7.4 6.9 4.2 6.6 5.1 12.8 32.1 2.6 9.8 3.5 12.5 15.3 9.9 9.1 2.0 19.0 14.6 16.7 17.2 12.3 14.7 0.0 6.6 0.2 179.2 19.6 7.9 2.9 17.5 8.2 11.7 21.7 0.0 5.4 18.5 6.8 6.0 71.4 36.2 5.7 2.9 11.4 81.7 19.9 0.0 8.5 114.8 14.2 9.8 19.0 3.1 6.8 8.5 39.2 9.4 12.8 6.7 0.0 3.5 0.9 32.9 77.1 7.2 7.6 35.5 55.3 3.8 8.9 2.6 32.9 2.2 8.5 6.1 15.7 8.4 11.5 3.4 1.9 4.1 88.9 33.1 TSHZ3 "KIAA1474, TSH3, ZNF537" ENSG00000121297 "Teashirt zinc finger homeobox 3" Q63HK5 19 31149979-31349436 "Disease related genes, Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "Developmental protein, DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "ovary: 32.8" "Cell type enhanced" "Detected in many" "Endometrial stromal cells: 54.0;Excitatory neurons: 34.4;Inhibitory neurons: 84.7;Oligodendrocyte precursor cells: 59.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "neutrophil: 1.9" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "ASC TERT1: 22.2;RH-30: 46.4;U-138 MG: 32.8;U-87 MG: 21.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA008834, HPA071010" Approved Enhanced "Nucleoplasm,Plasma membrane" No No "Cluster 9: Neutrophils - Innate immune response" "Cluster 89: Fibroblasts - ECM organization" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 8: Neurons & Oligodendrocytes - Synaptic function" Nucleoplasm "Plasma membrane" "HPA008834: AB_1080731, HPA071010: " "unprognostic (2.56e-1)" "unprognostic (3.88e-1)" "unprognostic (4.56e-2)" "unprognostic (3.66e-1)" "unprognostic (1.66e-3)" "unprognostic (4.07e-2)" "unprognostic (1.67e-1)" "unprognostic (2.46e-1)" "unprognostic (1.76e-1)" "unprognostic (3.58e-3)" "unprognostic (2.23e-1)" "unprognostic (3.91e-2)" "prognostic unfavorable (2.92e-4)" "unprognostic (8.76e-3)" "unprognostic (8.22e-2)" "unprognostic (1.91e-2)" "unprognostic (1.73e-3)" 7.0 3.6 4.6 4.8 4.5 1.1 6.2 0.0 8.6 18.8 0.3 16.1 2.2 21.5 9.2 5.7 13.0 9.3 5.7 5.7 0.4 3.2 1.3 6.3 1.2 3.1 1.0 32.8 1.5 1.3 4.6 5.7 1.5 11.6 4.0 1.8 3.3 9.5 1.9 3.0 5.5 18.4 3.9 5.4 6.7 2.7 3.1 0.8 10.2 2.3 0.5 14.8 8.8 4.9 0.0 2.0 0.7 0.0 9.4 22.2 0.0 6.0 8.8 3.7 6.6 0.0 1.2 0.0 0.0 14.8 7.0 1.0 2.7 5.3 8.2 0.0 2.2 0.0 0.0 0.0 19.4 5.2 9.1 13.0 4.5 13.7 6.8 0.0 0.0 4.4 0.0 0.0 16.9 0.9 0.0 0.0 0.7 0.0 0.0 5.9 46.4 0.0 0.0 0.0 0.0 13.8 0.1 0.0 4.7 4.4 0.0 3.6 0.0 32.8 10.3 3.4 8.8 0.0 0.0 0.0 21.2 8.8 0.9 0.0 0.9 0.0 1.1 0.3 0.0 0.0 0.3 0.4 0.0 0.0 0.1 0.3 1.9 0.0 0.1 0.0 0.3 0.3 4.6 4.5 0.0 8.6 5.7 0.4 3.1 1.0 1.5 3.9 3.1 4.9 8.3 3.2 1.1 10.1 0.2 4.8 7.3 9.2 15.4 14.0 0.8 2.4 2.1 1.5 5.1 3.7 0.0 0.4 2.5 0.0 0.0 0.4 0.2 1.3 54.0 9.0 0.0 0.4 34.4 0.6 0.3 20.2 0.0 1.3 1.3 2.6 17.2 0.2 11.6 16.8 84.7 0.0 2.0 9.7 10.4 1.1 17.7 5.0 5.4 14.0 6.4 0.2 0.0 59.3 1.9 0.6 0.0 29.3 0.3 3.8 0.0 0.1 1.3 0.2 0.0 29.7 7.8 0.3 4.0 1.7 1.7 0.8 1.7 1.0 0.0 3.2 TTC17 FLJ10890 ENSG00000052841 "Tetratricopeptide repeat domain 17" Q96AE7 11 43358920-43494933 "Predicted intracellular proteins" "Cilium biogenesis/degradation" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA038508 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 31: Non-specific - Inflammatory response" "Cluster 29: Non-specific - Vesicular transport" "Cluster 30: Epithelial cell lines - Translation" "Cluster 59: Non-specific - Transcription" "Plasma membrane" Cytosol "HPA038508: AB_10671744" "unprognostic (2.71e-1)" "unprognostic (4.04e-3)" "unprognostic (6.48e-2)" "unprognostic (2.64e-1)" "unprognostic (1.17e-1)" "unprognostic (5.66e-2)" "unprognostic (1.74e-1)" "unprognostic (9.03e-2)" "unprognostic (5.01e-3)" "unprognostic (2.62e-1)" "unprognostic (1.34e-2)" "unprognostic (1.90e-2)" "prognostic unfavorable (4.75e-6)" "unprognostic (1.04e-2)" "unprognostic (4.40e-1)" "unprognostic (1.18e-1)" "unprognostic (1.54e-2)" 20.7 18.7 11.0 16.1 11.3 15.5 28.6 16.7 12.2 22.0 22.0 21.2 21.6 26.9 25.0 14.2 28.4 22.3 13.5 11.1 12.2 19.4 38.6 24.2 20.2 11.9 12.5 40.9 49.5 27.7 12.3 29.2 11.7 25.4 22.9 25.1 40.7 21.4 16.4 19.5 25.5 23.0 11.0 23.4 27.4 24.8 12.4 24.6 36.9 20.0 22.4 18.8 15.6 13.0 15.0 30.4 31.3 49.3 77.2 63.6 22.1 35.6 47.6 29.3 35.1 21.1 21.7 31.6 34.9 35.9 33.7 31.1 22.3 23.5 35.2 24.5 29.0 24.2 19.5 20.8 95.3 36.6 29.9 59.5 69.8 21.3 68.4 66.2 29.5 22.7 35.5 26.2 29.8 18.1 27.1 20.3 46.8 58.0 25.0 25.1 33.3 36.9 37.2 21.4 16.7 39.7 27.7 73.1 44.6 31.4 68.6 40.8 39.6 41.7 18.4 47.1 52.1 51.1 44.5 29.8 26.9 21.6 45.3 20.0 21.7 19.0 14.9 22.4 15.9 16.4 16.2 14.5 16.9 14.8 16.3 15.1 18.5 16.5 20.8 17.6 16.1 18.0 11.0 11.3 16.7 12.2 11.1 12.2 11.9 12.5 11.7 11.0 12.4 13.0 43.0 64.1 62.7 159.6 53.3 42.1 35.0 36.4 30.7 44.1 40.3 35.7 20.5 31.5 51.9 22.0 60.5 32.6 43.8 30.7 3.9 23.1 52.6 35.8 44.5 40.9 22.3 44.0 204.6 43.4 28.8 44.4 40.2 48.6 36.6 56.2 40.0 57.5 26.2 47.1 203.2 42.1 34.6 48.0 32.3 18.4 57.2 37.1 28.4 181.8 47.8 24.8 37.0 192.0 200.6 29.7 31.5 36.5 48.9 50.1 47.7 15.5 54.3 47.3 52.6 45.5 36.2 51.8 35.0 34.6 43.2 30.8 45.6 33.5 35.8 42.7 TTLL12 KIAA0153 ENSG00000100304 "Tubulin tyrosine ligase like 12" Q14166 22 43166622-43187134 "Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "esophagus: 104.5" "Cell type enhanced" "Detected in many" "Distal enterocytes: 56.3;Paneth cells: 56.9;Squamous epithelial cells: 60.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA003054, CAB046029" Approved Approved "Plasma membrane,Cytosol" NA NA 140000 "Cluster 39: Non-specific - mRNA processing" "Cluster 37: Intestine - Unknown function" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 61: Squamous epithelial cells - Keratinization" Cytosol "Plasma membrane" "CAB046029: AB_11128395, HPA003054: AB_2666770" "unprognostic (2.45e-2)" "unprognostic (3.47e-2)" "unprognostic (7.37e-3)" "unprognostic (5.40e-2)" "unprognostic (2.65e-1)" "unprognostic (3.50e-1)" "prognostic unfavorable (2.84e-4)" "unprognostic (5.81e-3)" "unprognostic (2.24e-1)" "unprognostic (6.08e-2)" "unprognostic (4.75e-2)" "unprognostic (1.73e-1)" "unprognostic (1.15e-1)" "unprognostic (1.17e-3)" "unprognostic (1.40e-1)" "unprognostic (6.66e-2)" "unprognostic (2.81e-2)" 13.9 28.1 8.7 16.6 8.5 26.2 13.0 10.0 15.1 25.8 1.8 35.6 24.4 13.9 3.6 104.5 13.9 18.5 10.2 9.5 9.7 9.0 21.0 9.3 11.2 16.2 8.7 23.7 19.2 9.4 14.7 7.2 15.8 15.2 19.5 4.7 21.9 6.8 12.6 36.8 22.9 7.1 6.5 10.7 33.4 25.7 8.1 8.0 9.1 7.9 12.9 15.5 37.0 9.1 113.2 46.7 18.5 45.9 27.8 19.0 59.7 36.3 12.8 34.1 17.8 76.2 62.7 107.9 43.0 30.3 16.7 78.8 77.3 66.5 8.7 13.6 123.3 26.5 73.6 66.4 43.5 120.2 26.4 30.2 79.3 40.8 43.4 18.3 36.5 52.1 166.1 24.8 16.1 104.4 84.1 65.2 67.4 78.9 46.1 84.4 63.5 155.6 28.7 36.6 56.2 23.2 77.1 111.2 41.6 8.4 44.0 52.9 35.2 22.7 31.7 44.1 51.4 41.6 55.4 81.0 25.7 60.8 31.4 0.0 2.3 0.3 2.6 1.2 2.5 1.8 2.5 1.9 1.8 1.1 2.4 1.7 0.6 2.3 1.7 1.6 1.8 1.9 8.7 8.5 10.0 15.1 9.5 9.7 16.2 8.7 15.8 6.5 8.1 9.1 3.7 6.4 6.7 3.6 6.4 11.2 11.4 11.0 17.1 8.5 13.5 9.9 4.5 17.2 7.6 7.3 4.2 8.8 3.2 56.3 5.9 14.2 1.0 5.0 9.5 5.8 9.1 39.1 8.0 8.6 19.0 6.0 34.1 14.7 0.0 14.3 8.2 35.0 9.8 0.0 8.5 30.6 10.2 14.2 2.9 2.6 8.7 7.5 10.6 1.9 7.7 4.2 4.1 3.0 2.2 25.8 56.9 17.0 9.4 28.7 32.1 8.3 5.0 5.6 0.0 5.2 7.2 2.0 12.2 60.2 18.2 4.1 5.9 13.4 39.9 13.7 TTLL5 KIAA0998 ENSG00000119685 "Tubulin tyrosine ligase like 5" Q6EMB2 14 75633625-75955079 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Transcription Ligase "Cone-rod dystrophy, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "testis: 57.4" "Cell type enhanced" "Detected in many" "Cone photoreceptor cells: 127.2;Early spermatids: 111.0;Excitatory neurons: 134.3;Inhibitory neurons: 114.2;Oligodendrocytes: 242.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA032128 Uncertain Supported "Plasma membrane,Cytosol" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 77: Retina - Visual perception" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Plasma membrane, Cytosol" "HPA032128: AB_10600835" "unprognostic (7.35e-2)" "unprognostic (7.29e-2)" "unprognostic (7.73e-2)" "unprognostic (1.10e-1)" "unprognostic (1.33e-1)" "unprognostic (5.96e-2)" "unprognostic (7.21e-5)" "unprognostic (1.26e-1)" "unprognostic (1.70e-1)" "unprognostic (7.93e-2)" "unprognostic (1.10e-2)" "unprognostic (3.43e-1)" "unprognostic (5.67e-3)" "unprognostic (1.70e-1)" "unprognostic (1.57e-1)" "unprognostic (8.97e-2)" "unprognostic (2.15e-2)" 5.5 5.5 3.7 6.0 6.0 11.7 7.1 7.1 7.2 7.3 15.0 6.2 4.7 8.0 7.2 7.8 11.6 6.5 5.8 3.8 6.6 6.2 4.1 6.5 5.1 10.5 6.4 7.1 4.9 11.1 5.4 7.5 10.6 6.9 7.3 23.9 6.5 6.9 4.7 7.1 4.5 8.6 6.4 4.1 5.9 57.4 6.4 10.1 7.8 5.8 7.5 6.1 6.4 12.0 22.8 16.2 13.9 14.5 10.9 16.8 12.9 13.1 15.9 15.4 19.9 10.3 20.8 6.4 7.2 13.9 11.3 21.3 12.3 21.7 29.3 7.6 7.3 12.5 16.8 11.3 9.3 9.2 11.5 13.1 10.6 19.4 21.5 16.8 33.8 17.5 7.2 10.5 15.7 32.1 15.6 12.6 9.9 18.0 16.6 9.5 19.6 8.8 15.0 22.2 18.4 11.6 27.5 20.2 6.8 11.0 27.6 9.8 38.1 20.5 18.0 18.5 12.2 8.8 13.5 14.6 20.7 10.4 13.9 11.6 2.0 1.7 2.6 2.0 2.4 2.3 2.5 2.7 3.2 1.8 2.9 2.7 2.4 2.3 2.5 3.4 2.2 1.4 3.7 6.0 7.1 7.2 3.8 6.6 10.5 6.4 10.6 6.4 6.4 12.0 7.1 3.2 10.1 71.8 6.1 5.0 5.5 5.4 8.0 10.9 17.3 11.6 8.7 17.2 10.2 11.0 127.2 8.1 8.5 7.6 3.9 7.1 111.0 37.4 11.9 10.7 7.7 5.0 134.3 5.3 13.2 9.3 8.6 10.8 12.6 11.7 19.6 7.4 5.6 0.0 114.2 6.5 16.2 5.8 5.1 93.1 12.5 6.6 5.4 82.4 8.5 10.0 6.2 78.4 242.9 6.1 11.9 11.7 7.6 6.2 6.0 2.4 40.1 80.1 13.1 9.5 6.0 37.7 16.4 9.0 6.3 6.0 8.3 9.1 8.0 4.6 TTYH1 ENSG00000167614 "Tweety family member 1" Q9H313 19 54415219-54436904 "Predicted membrane proteins, Transporters" "Cell adhesion, Ion transport, Transport" "Chloride channel, Ion channel" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 80.9;choroid plexus: 35.6;testis: 53.4" "Cell type enhanced" "Detected in many" "Astrocytes: 257.6;Bipolar cells: 138.6;Muller glia cells: 653.4;Oligodendrocytes: 97.5;Rod photoreceptor cells: 155.3" "Cancer enriched" "Detected in many" 15 "glioma: 63.9" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AF22: 7.9;AN3-CA: 11.7;U-2 OS: 2.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA005725, HPA023617, HPA050655" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 23: AN3-CA - Transcription regulation" "Cluster 5: Muller glia cells - Visual perception" "Nucleoplasm, Plasma membrane" "HPA005725: , HPA023617: AB_10600836, HPA050655: AB_2681204" "prognostic favorable (3.64e-4)" "unprognostic (1.71e-1)" "unprognostic (1.24e-2)" "unprognostic (1.25e-1)" "unprognostic (1.46e-2)" "unprognostic (2.50e-3)" "unprognostic (8.93e-2)" "unprognostic (1.51e-2)" "unprognostic (5.94e-3)" "unprognostic (1.11e-1)" "unprognostic (3.66e-1)" "unprognostic (1.60e-1)" "unprognostic (0.00e+0)" "unprognostic (2.09e-1)" "unprognostic (1.41e-1)" "unprognostic (4.45e-2)" "unprognostic (1.69e-1)" 0.9 0.9 64.3 0.0 67.9 0.0 3.5 64.0 80.9 4.0 35.6 10.0 0.2 1.6 0.0 1.1 10.4 0.2 3.6 57.6 59.7 1.2 0.7 0.2 0.0 69.4 66.5 1.5 19.4 0.0 17.7 0.0 63.5 3.5 0.0 3.2 3.6 0.4 3.3 5.9 2.6 0.0 67.6 1.4 2.5 53.4 69.3 0.0 0.3 0.0 0.0 1.7 4.2 66.8 0.1 0.0 7.9 11.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.5 0.1 0.0 0.0 0.0 0.2 0.8 0.0 0.0 0.2 0.3 0.0 0.1 0.8 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.1 0.1 1.7 0.0 0.1 0.1 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.4 0.4 0.0 0.2 0.0 0.0 0.1 2.9 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 64.3 67.9 64.0 80.9 57.6 59.7 69.4 66.5 63.5 67.6 69.3 66.8 0.4 3.2 0.6 257.6 0.4 0.8 1.2 0.6 0.0 138.6 44.3 42.2 1.3 4.3 3.0 0.0 20.9 0.9 1.3 0.2 0.0 30.4 3.9 0.3 0.9 2.8 1.2 0.0 26.4 0.6 0.7 1.5 0.0 0.7 0.0 13.7 0.7 0.1 0.3 10.1 3.3 0.0 0.0 0.0 1.5 4.8 1.8 0.3 23.2 19.7 0.3 653.4 0.0 48.2 97.5 2.2 0.0 0.7 0.1 1.9 0.4 0.7 2.8 155.3 6.6 2.3 7.8 2.2 5.1 0.0 0.9 4.2 0.6 0.5 0.3 1.9 TXNDC11 EFP1 ENSG00000153066 "Thioredoxin domain containing 11" Q6PKC3 16 11679083-11742857 "Predicted intracellular proteins, Predicted membrane proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enriched" "Detected in all" 6 "Plasma cells: 307.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "RPMI-8226: 141.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041174, HPA041390" Supported Supported "Plasma membrane,Cytosol" No No "Cluster 26: Non-specific - Mitochondria" "Cluster 3: T-cells - Adaptive immune response" "Cluster 25: RPMI-8226 - Immune response" "Cluster 55: Plasma cells - Humoral immune response" "Plasma membrane, Cytosol" "HPA041174: AB_10794191, HPA041390: AB_10796670" "unprognostic (1.96e-2)" "unprognostic (1.43e-1)" "unprognostic (6.82e-3)" "prognostic favorable (2.12e-5)" "prognostic unfavorable (1.36e-4)" "unprognostic (2.43e-2)" "unprognostic (1.83e-1)" "unprognostic (2.68e-3)" "unprognostic (4.90e-2)" "unprognostic (2.17e-1)" "unprognostic (1.08e-1)" "unprognostic (2.01e-1)" "unprognostic (2.35e-2)" "unprognostic (9.96e-2)" "unprognostic (8.30e-2)" "unprognostic (3.23e-2)" "unprognostic (2.34e-2)" 15.7 14.2 4.5 22.5 5.6 55.4 16.6 7.7 5.9 20.8 16.6 30.0 38.5 15.1 23.6 13.1 16.2 17.3 13.7 5.0 4.9 25.7 44.3 34.9 25.3 4.8 4.8 16.6 26.5 45.1 12.6 17.0 4.8 24.4 29.8 15.3 34.8 14.9 30.1 12.0 32.0 15.6 4.6 22.4 36.1 8.5 4.9 20.6 34.4 14.9 27.9 25.3 11.8 5.0 26.1 17.7 8.2 11.2 21.6 18.0 14.4 25.3 34.5 22.7 29.1 8.8 40.5 65.2 41.6 32.0 30.9 22.9 10.2 21.4 18.5 29.4 13.5 13.9 19.4 43.8 31.7 20.6 27.1 13.7 23.6 25.4 39.9 17.6 28.9 14.6 21.5 81.8 20.2 23.7 16.1 7.9 10.7 18.6 9.1 20.5 16.5 141.9 26.0 13.7 11.5 10.9 49.6 38.2 27.3 9.1 23.4 28.1 30.1 10.5 12.0 49.8 14.7 110.5 64.8 39.5 22.3 25.7 17.9 3.5 2.4 7.7 1.8 1.7 4.5 3.8 3.3 4.1 2.6 4.6 3.2 2.1 0.7 5.6 2.2 2.0 6.8 2.8 4.5 5.6 7.7 5.9 5.0 4.9 4.8 4.8 4.8 4.6 4.9 5.0 16.2 44.8 46.2 21.9 49.2 14.7 24.8 12.9 23.3 16.2 16.1 18.0 9.1 18.6 24.6 18.4 50.1 21.1 27.2 45.8 15.6 20.4 3.1 19.9 14.6 15.2 24.5 6.5 23.0 39.7 29.8 14.0 45.3 28.5 15.2 13.0 15.7 39.3 30.3 23.5 25.5 44.0 8.2 18.1 26.9 1.4 20.2 29.2 23.2 18.7 21.2 16.4 15.5 22.1 18.6 26.1 21.0 13.2 307.9 28.0 37.1 15.2 15.9 23.4 6.6 13.8 16.2 11.6 13.1 17.5 11.8 25.0 25.2 11.3 27.7 32.1 TXNIP "ARRDC6, EST01027, HHCPA78, THIF, VDUP1" ENSG00000265972 "Thioredoxin interacting protein" Q9H3M7 1 145992435-145996579 "Cancer-related genes, Predicted intracellular proteins" "Cell cycle, Transcription, Transcription regulation" "Cancer-related genes, Tumor suppressor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 2550.5;NK-cells: 2028.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "ASC TERT1: 951.8;HSkMC: 1276.5;hTCEpi: 664.0;hTERT-RPE1: 781.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA031085, HPA053694" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 50: Fibroblasts - ECM organization" "Plasma membrane" Cytosol "HPA031085: AB_10601706, HPA053694: AB_2682232" "unprognostic (1.45e-1)" "unprognostic (1.57e-2)" "unprognostic (1.67e-2)" "unprognostic (4.16e-2)" "unprognostic (1.92e-2)" "unprognostic (3.93e-2)" "unprognostic (1.55e-2)" "unprognostic (2.51e-1)" "unprognostic (9.23e-2)" "unprognostic (1.20e-1)" "unprognostic (3.65e-2)" "unprognostic (1.19e-1)" "unprognostic (8.49e-3)" "unprognostic (1.35e-2)" "unprognostic (1.31e-1)" "unprognostic (8.19e-2)" "unprognostic (2.22e-3)" 1542.7 466.8 130.3 566.5 159.9 404.7 1396.7 137.1 158.5 846.0 133.8 965.4 223.3 811.8 381.2 428.7 730.3 395.0 745.2 120.3 136.6 532.6 204.0 841.9 800.8 182.0 144.9 382.9 580.5 634.0 192.3 594.0 185.4 352.4 487.5 14.5 567.0 554.5 1446.1 1060.4 810.7 658.7 157.1 946.4 713.4 106.4 159.2 373.7 556.6 2306.2 1068.8 740.9 638.7 217.3 56.5 0.2 13.0 0.9 291.6 951.8 29.7 66.0 131.3 58.5 79.7 35.3 74.6 15.8 379.6 18.1 9.7 15.0 13.0 124.8 154.8 74.2 7.1 45.7 20.2 32.6 13.8 189.7 91.7 1276.5 664.0 119.0 206.7 781.9 23.2 61.8 184.8 121.2 30.2 76.5 31.9 180.2 36.3 112.5 48.5 28.5 107.8 498.3 151.6 122.8 61.7 99.9 283.1 80.5 239.0 26.2 29.1 266.6 56.5 160.1 10.0 304.2 108.7 169.3 170.7 13.8 39.3 86.6 86.3 1059.6 571.2 1219.2 792.2 551.3 729.8 519.3 668.8 710.4 334.4 542.4 650.2 708.5 1246.6 637.1 496.3 154.8 674.5 1684.4 130.3 159.9 137.1 158.5 120.3 136.6 182.0 144.9 185.4 157.1 159.2 217.3 2550.5 227.6 328.5 26.4 1360.4 70.7 236.9 129.8 413.8 6.5 167.4 111.2 526.0 185.8 184.4 272.2 29.2 5.0 1004.6 578.0 450.0 79.7 8.3 179.8 594.5 740.2 164.2 270.8 0.2 53.8 4.1 666.5 160.5 464.2 377.4 53.6 349.8 114.8 231.9 6.7 0.5 320.9 136.3 845.1 184.9 35.5 654.5 730.8 108.5 36.5 892.0 3.6 2028.9 45.2 55.8 225.7 459.4 447.2 639.6 370.7 79.0 169.3 155.8 3.7 1196.5 452.4 398.7 7.6 63.7 160.1 72.2 10.9 1142.8 303.9 186.9 516.2 TYW3 "C1orf171, FLJ40918" ENSG00000162623 "TRNA-yW synthesizing protein 3 homolog" Q6IPR3 1 74733152-74766678 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "tRNA processing" "Methyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA029641 Approved Approved "Plasma membrane,Cytosol" No No "Cluster 44: Non-specific - Transcription" "Cluster 89: Fibroblasts - ECM organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" Cytosol "Plasma membrane" "HPA029641: AB_2272535" "unprognostic (6.89e-3)" "unprognostic (1.06e-1)" "unprognostic (1.08e-1)" "unprognostic (1.09e-1)" "unprognostic (1.42e-1)" "unprognostic (7.24e-2)" "prognostic unfavorable (1.49e-7)" "unprognostic (3.79e-1)" "unprognostic (2.23e-1)" "unprognostic (2.96e-1)" "unprognostic (4.08e-2)" "unprognostic (1.59e-1)" "unprognostic (1.70e-1)" "unprognostic (1.13e-1)" "unprognostic (2.05e-1)" "unprognostic (8.90e-2)" "unprognostic (2.98e-3)" 12.9 15.4 10.8 11.7 11.8 13.1 17.0 11.3 12.7 13.4 10.2 15.2 8.9 16.0 12.2 11.6 14.7 9.2 20.3 10.5 12.5 17.4 13.8 10.6 14.6 11.2 12.1 26.6 11.7 21.5 11.7 12.7 11.8 15.1 11.1 14.6 14.0 13.6 10.6 9.9 8.9 17.9 11.5 11.0 11.5 11.9 11.6 12.7 19.2 14.4 16.4 15.2 11.1 13.2 19.6 16.1 27.3 19.5 30.3 32.9 41.4 32.9 30.0 30.7 26.9 34.3 16.2 51.0 29.4 28.6 45.1 15.6 31.5 37.9 38.3 31.9 27.1 40.2 49.4 67.0 19.9 81.2 24.9 25.1 37.7 39.2 37.6 24.7 27.7 34.8 70.8 38.0 39.9 16.6 39.8 27.1 72.8 29.2 37.2 37.2 56.8 23.0 26.6 25.2 21.1 18.0 15.7 42.4 53.7 29.5 23.2 29.3 18.2 13.6 37.0 37.0 40.2 21.9 42.7 35.4 30.3 29.0 39.9 9.1 6.4 1.8 10.6 8.8 10.0 10.7 9.2 9.7 9.9 9.8 13.2 14.2 0.5 15.4 6.9 9.6 9.4 5.8 10.8 11.8 11.3 12.7 10.5 12.5 11.2 12.1 11.8 11.5 11.6 13.2 30.6 16.0 23.9 17.6 34.1 25.6 40.5 32.7 58.1 34.5 32.4 42.3 29.9 20.0 28.6 16.5 4.2 44.5 21.2 7.4 78.2 36.2 19.8 28.9 38.8 31.7 13.8 18.5 28.0 59.4 51.1 34.7 15.8 29.0 21.0 32.8 21.8 29.2 33.1 50.5 22.7 19.5 22.4 30.9 22.6 19.6 43.5 26.2 21.4 14.0 39.5 27.6 37.0 30.2 24.5 32.5 8.4 61.3 35.6 45.7 12.2 64.4 18.4 22.5 13.1 44.2 36.0 34.3 45.3 44.1 22.7 22.3 29.2 55.7 25.9 31.2 UBE2C UBCH10 ENSG00000175063 "Ubiquitin conjugating enzyme E2 C" O00762 20 45812576-45816957 "Cancer-related genes, Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Mitosis, Ubl conjugation pathway" Transferase "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 78.5;lymphoid tissue: 113.5" "Cell type enhanced" "Detected in many" "Cytotrophoblasts: 129.6;Erythroid cells: 182.1;Extravillous trophoblasts: 449.1;Granulosa cells: 119.0" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in single" "Immune cell enhanced" "Detected in some" "T-reg: 8.2" "Group enriched" "Detected in many" 5 "granulocytes: 2.1;NK-cells: 2.1;T-cells: 8.2" "Low cell line specificity" "Detected in all" "Group enriched" "Detected in many" 5 "basal ganglia: 4.3;white matter: 11.4" "Low region specificity" "Detected in some" "CAB011464, HPA034569, CAB035990, HPA054975" Approved Approved "Plasma membrane,Cytosol" Yes Yes "Cluster 35: T-regs - Unknown function" "Cluster 53: Non-specific - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 12: Non-specific - Cell cycle regulation" "Plasma membrane, Cytosol" "CAB011464: AB_442965, CAB035990: , HPA034569: AB_2674226, HPA054975: AB_2682658" "unprognostic (1.45e-2)" "unprognostic (2.19e-1)" "unprognostic (1.06e-1)" "unprognostic (2.11e-3)" "unprognostic (2.54e-1)" "unprognostic (1.35e-1)" "prognostic unfavorable (6.24e-6)" "unprognostic (2.27e-3)" "unprognostic (2.59e-2)" "unprognostic (1.04e-1)" "prognostic unfavorable (6.91e-4)" "unprognostic (3.76e-2)" "prognostic unfavorable (0.00e+0)" "unprognostic (3.09e-1)" "unprognostic (3.61e-1)" "unprognostic (4.65e-2)" "unprognostic (2.68e-1)" 2.6 2.9 0.3 21.5 0.3 78.5 4.3 0.9 0.6 6.1 0.7 26.7 21.4 5.7 0.6 37.2 1.9 2.7 1.4 0.2 0.3 1.9 2.9 5.4 45.3 0.3 0.7 1.3 1.0 0.4 0.4 20.4 0.7 1.5 30.9 0.2 5.0 0.9 0.9 18.5 20.6 10.5 0.2 15.8 13.0 16.4 1.6 113.5 1.1 0.2 69.5 6.9 12.3 0.4 312.8 223.9 390.9 188.3 10.4 24.0 225.2 238.5 121.6 390.7 278.4 743.8 345.4 327.6 233.2 115.5 475.6 294.9 2.2 260.5 395.8 141.7 213.7 101.5 168.5 196.0 3.0 145.4 241.6 7.6 27.8 265.7 257.3 57.4 193.4 206.4 1.8 261.6 325.4 516.2 243.5 41.1 237.1 350.8 529.4 256.0 354.8 1.4 134.9 105.9 226.1 188.7 378.3 271.7 154.4 196.2 276.6 209.4 70.1 341.2 298.4 236.2 473.4 84.3 2.9 369.4 208.0 103.4 328.6 0.0 0.0 0.0 0.1 0.0 0.0 0.9 0.8 1.7 0.6 0.1 0.1 0.1 2.1 2.1 0.5 0.3 8.2 3.2 0.3 0.3 0.9 0.6 0.2 0.3 0.3 0.7 0.7 0.2 1.6 0.4 0.9 0.0 3.7 0.0 17.9 17.3 7.8 39.0 5.7 0.0 8.6 14.6 0.0 1.5 9.3 0.0 0.0 129.6 3.6 27.4 0.0 1.3 12.0 5.8 5.9 9.5 1.2 182.1 0.0 0.5 449.1 28.5 25.5 9.6 5.7 119.0 18.2 3.6 92.6 0.0 0.1 41.1 50.8 20.8 18.1 6.4 0.9 24.1 0.0 0.0 1.1 0.0 0.0 0.0 0.0 1.5 7.2 0.0 37.0 12.6 6.2 0.6 1.8 0.0 0.0 0.5 19.2 52.2 50.7 83.2 11.6 31.2 13.7 2.5 68.4 18.4 UBE2D1 "E2(17)KB1, SFT, UBC4/5, UBCH5, UbcH5A" ENSG00000072401 "Ubiquitin conjugating enzyme E2 D1" P51668 10 58334979-58370751 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 138.7;tongue: 65.3" "Cell type enhanced" "Detected in all" "Basal keratinocytes: 194.4;Suprabasal keratinocytes: 190.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 112.3" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.12e-1)" "unprognostic (2.08e-1)" "unprognostic (4.23e-3)" "unprognostic (1.76e-1)" "unprognostic (1.52e-2)" "unprognostic (1.21e-2)" "prognostic unfavorable (5.58e-4)" "unprognostic (2.20e-2)" "unprognostic (1.03e-1)" "unprognostic (2.24e-2)" "unprognostic (4.37e-3)" "unprognostic (2.17e-1)" "prognostic unfavorable (8.04e-6)" "unprognostic (9.71e-3)" "unprognostic (4.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.66e-2)" 13.0 11.8 5.3 16.7 5.7 32.4 7.8 6.6 8.1 8.9 4.4 11.4 7.0 12.6 7.5 11.6 7.1 9.5 33.3 6.1 6.2 8.1 8.3 8.9 13.8 6.6 6.4 8.4 5.5 8.9 3.9 8.9 6.6 9.5 12.0 5.4 5.5 6.7 138.7 5.9 8.3 13.6 6.4 13.4 6.4 4.5 6.3 7.8 8.4 65.3 11.4 15.1 5.6 6.7 19.1 10.2 18.8 24.4 37.5 30.0 12.1 12.4 21.2 13.9 20.3 20.9 16.4 0.0 19.0 18.6 10.3 17.1 36.6 18.0 19.5 19.8 21.2 4.9 3.7 12.2 24.4 15.3 11.8 34.8 19.9 14.4 26.8 18.7 28.1 13.1 10.0 7.8 19.1 6.1 16.5 17.1 23.0 11.7 15.7 13.8 16.9 10.6 21.2 11.2 14.0 18.8 24.2 40.3 20.6 28.5 14.8 10.2 22.8 5.3 18.6 18.2 13.7 19.7 16.4 16.8 16.7 31.3 6.2 10.1 38.5 17.8 6.2 27.1 7.2 8.9 7.3 7.9 20.0 9.8 7.5 6.2 112.3 8.2 23.4 8.3 9.8 23.4 5.3 5.7 6.6 8.1 6.1 6.2 6.6 6.4 6.6 6.4 6.3 6.7 41.6 12.8 11.2 5.5 54.3 194.4 94.1 60.6 46.1 23.7 45.6 45.5 92.4 17.2 39.0 27.6 18.8 29.9 41.7 27.4 76.3 62.3 5.0 32.6 46.9 42.5 41.7 12.0 18.5 42.0 50.4 51.9 38.7 51.2 22.9 19.6 27.5 15.6 73.7 16.8 17.1 40.1 69.2 90.6 104.0 3.0 33.2 147.7 53.4 4.7 94.6 17.9 22.6 12.5 21.2 81.2 52.7 32.4 26.4 108.4 16.1 54.3 33.6 16.1 6.6 51.4 59.1 33.5 19.9 47.1 190.2 149.0 42.8 14.9 28.5 118.2 UBE2D2 "UBC4, UbcH5B" ENSG00000131508 "Ubiquitin conjugating enzyme E2 D2" P62837 5 139526431-139628434 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Transporters" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 26: Non-specific - Mitochondria" "Cluster 23: Testis - Cell cycle regulation" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (1.14e-1)" "unprognostic (2.75e-3)" "prognostic favorable (5.09e-5)" "prognostic favorable (5.90e-4)" "unprognostic (2.33e-1)" "unprognostic (8.19e-3)" "prognostic unfavorable (9.63e-7)" "unprognostic (7.41e-3)" "unprognostic (2.17e-1)" "unprognostic (1.21e-1)" "unprognostic (9.33e-2)" "unprognostic (1.41e-3)" "prognostic unfavorable (2.09e-5)" "unprognostic (8.00e-2)" "unprognostic (1.01e-1)" "unprognostic (4.20e-1)" "unprognostic (1.07e-1)" 78.4 59.9 75.8 66.9 82.0 106.9 72.6 79.3 84.2 84.2 63.0 106.8 46.5 72.8 102.6 89.0 95.0 49.8 93.7 77.9 85.8 80.1 82.6 77.0 83.5 78.7 80.4 64.3 66.5 72.8 62.3 65.5 80.0 57.0 92.8 77.2 61.0 72.3 190.3 77.9 70.4 74.3 81.9 79.3 70.2 135.6 80.1 128.0 61.3 127.3 140.2 79.7 72.8 86.4 175.9 113.9 194.3 137.0 127.9 161.7 125.4 179.6 165.5 204.7 238.6 292.0 160.6 247.8 229.1 185.7 254.0 108.8 192.6 300.2 272.5 162.4 113.7 140.1 115.0 172.1 249.9 136.9 119.7 129.9 152.0 204.9 301.8 177.4 221.8 159.5 125.0 203.1 192.9 175.5 215.3 197.2 108.1 60.4 124.0 162.7 198.1 179.6 220.4 202.0 177.5 117.0 157.1 198.7 309.4 413.4 125.2 121.6 148.9 156.4 87.6 132.5 223.5 146.0 260.0 343.8 112.3 223.2 128.0 44.1 57.0 115.9 57.7 53.7 62.1 89.2 82.1 80.9 63.3 90.7 102.5 90.3 90.7 65.1 66.2 106.1 110.8 58.0 75.8 82.0 79.3 84.2 77.9 85.8 78.7 80.4 80.0 81.9 80.1 86.4 137.1 32.1 69.8 35.9 215.4 171.8 182.3 204.8 112.7 76.3 124.8 146.9 96.4 124.4 96.5 68.0 81.3 181.4 205.8 158.0 215.2 208.4 637.0 457.2 94.2 131.0 123.4 148.8 62.0 178.4 228.0 104.8 77.5 230.9 138.8 119.4 109.9 80.6 178.0 94.2 54.4 120.8 142.4 136.4 203.4 550.0 104.4 150.8 152.9 49.6 189.5 170.7 234.8 38.2 65.7 228.7 127.1 93.6 237.3 234.8 123.8 200.9 63.9 105.1 118.3 102.2 171.2 459.7 152.5 149.4 203.7 249.6 217.1 111.7 160.4 247.1 UBE2D3 UbcH5C ENSG00000109332 "Ubiquitin conjugating enzyme E2 D3" P61077 4 102794383-102868896 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Apoptosis, DNA damage, DNA repair, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA003920 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 9: Neutrophils - Innate immune response" "Cluster 55: Non-specific - Mitochondria & Proteasome" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (7.43e-2)" "unprognostic (3.19e-1)" "unprognostic (1.27e-2)" "unprognostic (5.78e-2)" "unprognostic (6.44e-2)" "unprognostic (4.96e-2)" "unprognostic (1.17e-1)" "unprognostic (8.44e-3)" "unprognostic (1.14e-1)" "unprognostic (1.95e-1)" "unprognostic (5.75e-2)" "unprognostic (3.31e-2)" "prognostic favorable (4.51e-4)" "unprognostic (5.08e-2)" "unprognostic (2.79e-1)" "unprognostic (4.54e-2)" "unprognostic (1.34e-2)" 182.7 171.7 85.7 172.0 92.6 478.3 141.9 101.1 120.6 127.1 93.4 154.9 154.0 125.3 113.8 173.4 125.9 142.5 149.4 92.1 103.9 172.2 251.4 175.3 189.6 102.5 96.0 131.5 154.2 133.5 98.4 159.0 99.8 106.8 144.4 129.0 116.7 102.1 243.6 136.4 158.3 129.9 101.4 149.5 144.4 127.0 95.6 198.5 159.2 197.9 197.0 185.6 128.0 113.7 301.6 169.1 275.4 223.4 286.2 408.0 235.9 301.2 395.1 260.1 243.6 257.4 416.4 319.3 190.6 304.4 336.8 168.6 294.7 400.8 352.5 299.6 149.8 292.0 165.8 209.6 300.3 415.5 240.4 314.0 247.9 288.6 398.9 334.3 343.4 258.7 372.9 316.4 350.9 243.1 613.4 235.1 200.2 341.0 167.1 318.4 269.9 231.5 261.5 283.7 275.6 232.1 183.5 464.8 349.6 318.2 193.0 241.0 318.4 270.0 231.1 179.2 276.3 277.9 389.8 491.3 288.2 227.2 297.0 614.9 253.7 394.0 163.5 256.0 216.3 165.9 203.4 194.4 217.6 139.2 205.8 190.5 817.2 215.7 271.9 149.8 229.6 422.1 85.7 92.6 101.1 120.6 92.1 103.9 102.5 96.0 99.8 101.4 95.6 113.7 303.4 166.7 193.1 98.9 291.7 844.0 693.9 408.2 233.9 133.7 251.5 166.9 229.8 193.0 242.3 139.8 125.1 311.5 317.4 336.1 547.8 361.0 779.4 257.1 246.7 344.0 240.8 348.7 159.7 382.2 561.6 286.0 202.3 371.3 224.9 154.8 193.1 235.7 392.9 122.8 145.8 283.8 303.2 403.0 825.6 635.1 164.7 415.1 357.5 111.5 399.4 160.0 280.2 104.5 185.0 454.4 347.2 149.0 296.4 612.3 335.8 428.8 242.4 170.6 105.2 270.6 531.9 217.2 180.7 258.2 813.3 638.4 382.5 172.3 268.2 784.3 UBE2D4 HBUCE1 ENSG00000078967 "Ubiquitin conjugating enzyme E2 D4 (putative)" Q9Y2X8 7 43926436-43956136 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 32.5" "Cell type enhanced" "Detected in many" "Distal tubular cells: 54.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in all" "SH-SY5Y: 30.2" "Low region specificity" "Detected in all" HPA003920 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 12: Non-specific - Basic cellular processes" "Cluster 80: Striated muscle - Unknown function" "Cluster 13: SH-SY5Y - Nervous system development" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA003920: AB_1858519" "unprognostic (9.95e-3)" "unprognostic (6.76e-2)" "unprognostic (6.87e-2)" "unprognostic (8.94e-2)" "unprognostic (8.24e-2)" "unprognostic (5.24e-2)" "unprognostic (2.42e-1)" "unprognostic (3.58e-3)" "unprognostic (4.74e-2)" "unprognostic (5.04e-2)" "prognostic favorable (4.86e-4)" "prognostic favorable (5.77e-4)" "prognostic favorable (6.51e-4)" "unprognostic (1.11e-1)" "unprognostic (8.74e-3)" "unprognostic (1.89e-1)" "unprognostic (1.34e-1)" 5.8 8.3 11.7 2.4 12.2 2.2 5.0 14.2 17.6 4.6 9.8 6.5 2.4 4.5 5.7 5.2 4.5 3.4 10.9 12.3 11.2 6.9 10.7 4.4 2.7 12.0 11.7 5.1 10.0 4.6 5.1 2.8 11.9 5.7 2.9 6.9 5.6 4.4 32.5 4.9 3.9 4.4 11.8 4.7 4.6 3.0 11.5 2.7 4.9 27.8 2.7 5.3 5.2 12.7 4.9 4.0 2.4 11.0 11.0 4.5 1.8 2.3 5.8 2.9 3.7 2.1 5.6 4.6 6.3 6.3 8.1 5.3 3.1 2.5 4.4 10.5 5.4 5.0 5.8 5.4 4.1 10.9 9.8 3.4 5.2 3.3 5.0 4.2 3.6 5.5 5.6 9.2 4.0 3.0 6.5 6.1 5.4 5.9 5.1 4.0 3.3 7.1 6.2 5.9 8.8 30.2 5.0 9.7 3.8 4.4 4.9 3.3 3.2 1.9 6.0 4.1 6.9 13.5 10.8 2.2 5.7 14.2 10.9 10.2 14.5 17.5 11.1 23.8 11.4 12.8 13.5 12.5 15.1 12.7 16.2 13.4 1.4 9.9 28.7 13.0 12.6 8.8 11.7 12.2 14.2 17.6 12.3 11.2 12.0 11.7 11.9 11.8 11.5 12.7 14.9 0.0 6.5 8.8 10.4 6.2 9.1 9.4 4.0 9.6 24.3 24.3 24.6 14.3 10.0 16.5 2.1 11.9 11.9 8.4 54.8 18.7 6.2 8.9 7.2 12.9 18.7 9.9 14.2 28.4 20.3 14.9 8.2 8.7 4.5 11.1 12.5 25.4 27.4 11.8 13.5 8.0 8.2 11.6 14.1 10.7 12.2 12.5 16.0 8.4 18.4 18.8 5.2 20.1 12.1 14.1 7.6 21.8 11.2 12.1 15.5 52.0 5.5 11.6 6.6 23.0 10.5 15.6 9.6 10.8 11.2 7.7 8.8 16.5 8.4 12.3 UBE2K "HIP2, HYPG, UBC1" ENSG00000078140 "Ubiquitin conjugating enzyme E2 K" P61086 4 39698109-39782792 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028869, CAB033212, CAB033515" Supported Approved "Plasma membrane,Cytosol" NA NA 390000 "Cluster 31: Non-specific - Inflammatory response" "Cluster 8: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 10: Non-specific - Unknown function" Cytosol "Plasma membrane" "CAB033212: AB_2272506, CAB033515: AB_2304024, HPA028869: AB_10602487" "unprognostic (1.14e-2)" "unprognostic (6.02e-2)" "unprognostic (2.42e-3)" "unprognostic (3.06e-1)" "unprognostic (6.81e-2)" "unprognostic (2.05e-1)" "unprognostic (5.05e-3)" "unprognostic (1.44e-2)" "unprognostic (2.71e-3)" "unprognostic (1.01e-1)" "prognostic unfavorable (8.60e-4)" "unprognostic (1.08e-1)" "unprognostic (3.67e-1)" "unprognostic (4.83e-2)" "unprognostic (6.88e-2)" "unprognostic (1.22e-1)" "unprognostic (4.10e-3)" 29.9 19.4 13.5 23.4 17.5 21.4 21.7 20.9 24.5 16.0 9.2 35.8 31.2 17.8 17.7 26.2 12.7 12.9 18.4 18.3 14.9 26.7 45.4 16.4 20.1 12.9 14.0 13.6 13.2 20.4 15.8 24.4 13.1 19.8 24.2 21.0 16.9 14.9 37.3 22.6 24.8 17.2 7.8 18.0 31.8 16.5 14.2 22.4 23.8 25.6 18.0 20.2 17.2 16.0 91.3 90.7 49.3 45.6 29.8 28.7 82.8 122.8 26.4 32.8 34.0 138.0 91.1 114.3 105.2 35.0 79.8 39.0 95.4 54.7 51.9 76.1 70.0 145.7 88.9 121.6 38.4 159.0 79.6 27.1 60.2 46.0 49.0 35.2 43.3 49.3 152.9 39.6 33.9 86.6 111.5 89.9 67.7 54.4 69.8 66.3 144.0 44.2 46.0 123.9 103.9 47.4 91.7 34.5 58.9 54.1 44.4 58.2 116.9 49.9 105.7 60.0 114.5 55.3 174.0 121.4 26.9 101.4 59.5 19.6 18.1 24.8 14.4 16.9 13.4 20.7 15.0 13.8 19.7 14.7 11.2 12.6 15.1 14.0 25.4 27.6 16.0 10.5 13.5 17.5 20.9 24.5 18.3 14.9 12.9 14.0 13.1 7.8 14.2 16.0 63.2 57.7 63.1 69.2 53.0 122.9 65.5 74.3 59.7 62.2 65.3 52.5 72.3 52.9 66.7 49.7 29.2 84.5 76.5 143.7 66.5 83.5 144.9 72.0 82.3 65.6 59.7 85.8 115.9 89.4 168.7 59.2 68.3 90.9 34.8 40.1 63.5 113.6 80.2 104.3 113.8 74.5 65.1 77.1 91.8 202.4 65.3 76.5 56.9 89.0 104.0 87.1 56.7 87.0 118.2 139.6 94.3 56.4 55.5 111.4 75.3 98.0 60.7 42.9 39.5 61.8 121.1 145.2 55.1 74.3 137.9 147.5 61.3 54.8 74.1 107.0 UBE2QL1 FLJ25076 ENSG00000215218 "Ubiquitin conjugating enzyme E2 Q family like 1" A1L167 5 6448859-6496723 "Disease related genes, Enzymes, Metabolic proteins, Potential drug targets, Predicted intracellular proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 5 "brain: 26.1;heart muscle: 16.8;retina: 28.3;skeletal muscle: 54.5;tongue: 13.9" "Cell type enhanced" "Detected in many" "Bipolar cells: 30.0;Cardiomyocytes: 27.6;Excitatory neurons: 47.8;Granulosa cells: 45.5;Horizontal cells: 45.4;Inhibitory neurons: 35.3;Rod photoreceptor cells: 63.6" "Cancer enhanced" "Detected in many" "thyroid cancer: 5.4" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "Karpas-707: 29.7;PC-3: 24.6;SCLC-21H: 23.1;U-266/70: 54.4;U-266/84: 52.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA057414 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 46: Photoreceptor cells - Phototransduction" Nucleoplasm "Plasma membrane" "HPA057414: " "unprognostic (1.45e-2)" "unprognostic (1.58e-2)" "unprognostic (1.79e-2)" "unprognostic (2.10e-1)" "unprognostic (1.08e-2)" "unprognostic (7.43e-2)" "unprognostic (1.15e-2)" "unprognostic (1.36e-1)" "unprognostic (3.10e-1)" "unprognostic (7.16e-2)" "unprognostic (2.15e-3)" "unprognostic (8.41e-2)" "prognostic favorable (6.81e-8)" "unprognostic (3.18e-3)" "unprognostic (2.81e-1)" "unprognostic (1.27e-2)" "unprognostic (1.41e-2)" 1.2 1.4 14.3 0.4 14.6 0.0 1.1 16.5 26.1 2.1 1.8 5.3 0.3 0.8 1.0 0.4 0.7 0.4 16.8 17.9 11.4 3.4 1.2 0.1 0.1 12.0 7.9 2.6 0.6 0.1 3.2 0.0 11.6 3.5 0.3 28.3 0.8 5.5 54.5 1.5 1.4 0.7 5.6 0.2 2.9 0.7 10.1 0.3 1.2 13.9 0.2 0.3 1.3 17.7 0.1 0.0 0.0 0.3 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 29.7 0.0 5.3 0.0 0.0 0.3 0.0 24.6 0.1 0.0 11.5 0.0 0.0 23.1 4.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 54.4 52.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 14.3 14.6 16.5 26.1 17.9 11.4 12.0 7.9 11.6 5.6 10.1 17.7 0.2 0.0 0.0 5.5 0.3 1.3 0.5 0.5 0.0 30.0 0.4 1.0 27.6 0.0 0.0 0.0 6.2 0.0 0.0 0.0 5.9 0.0 0.0 0.2 0.4 1.0 5.4 0.0 47.8 0.2 0.0 3.6 1.1 0.1 0.0 45.5 0.0 1.0 0.1 45.4 35.3 0.0 0.0 0.3 0.3 0.3 4.1 0.1 0.0 2.8 0.0 9.4 0.0 12.1 5.4 0.1 0.0 6.8 1.8 0.9 0.0 0.2 0.0 63.6 0.0 3.2 1.4 0.1 0.3 0.0 0.1 0.0 0.0 0.5 0.0 0.0 UBE2S E2-EPF ENSG00000108106 "Ubiquitin conjugating enzyme E2 S" Q16763 19 55399745-55407788 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Cell cycle, Cell division, Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 115.9;testis: 158.3" "Cell type enhanced" "Detected in many" "Breast myoepithelial cells: 341.4;dendritic cells: 432.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB015228, HPA057150" Approved Approved "Nucleoplasm,Plasma membrane" NA Yes "Cluster 37: B-cells - Transcription" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane" Nucleoplasm "CAB015228: , HPA057150: AB_2683351" "unprognostic (2.79e-1)" "unprognostic (2.42e-1)" "unprognostic (2.57e-1)" "prognostic unfavorable (2.05e-4)" "unprognostic (9.54e-2)" "unprognostic (1.41e-1)" "prognostic unfavorable (8.00e-6)" "unprognostic (1.42e-3)" "unprognostic (2.32e-1)" "unprognostic (2.31e-1)" "unprognostic (8.08e-2)" "unprognostic (4.52e-2)" "prognostic unfavorable (8.16e-8)" "unprognostic (1.05e-1)" "unprognostic (9.51e-2)" "unprognostic (1.58e-1)" "unprognostic (1.75e-1)" 16.3 17.6 17.1 21.8 17.3 115.9 11.0 15.7 23.7 16.8 10.9 18.5 11.4 17.2 5.5 37.1 15.1 13.1 24.8 25.2 23.8 13.0 11.5 16.2 35.7 17.0 16.5 14.8 7.7 6.8 28.8 13.6 22.2 15.1 9.3 9.4 12.0 6.2 15.5 12.0 16.2 15.0 16.7 25.7 17.6 158.3 18.9 47.8 10.3 5.7 30.9 16.2 17.8 21.3 532.9 279.4 241.3 193.8 15.3 21.6 42.9 419.3 126.1 253.2 229.1 191.1 183.6 508.6 169.5 106.4 304.5 152.9 243.6 109.5 111.4 402.0 810.5 305.8 162.8 62.5 45.1 370.0 286.0 23.8 30.2 186.7 179.1 55.0 100.6 272.7 310.0 347.0 161.3 139.5 503.2 191.3 605.3 147.2 470.6 437.4 185.5 185.8 69.2 111.5 609.3 330.0 534.5 131.2 248.6 72.6 93.8 198.1 155.9 151.9 432.8 130.7 1013.5 277.1 734.4 617.0 159.2 257.5 562.7 0.5 0.8 1.3 0.7 0.6 0.5 2.5 1.0 1.0 0.6 0.6 1.0 0.5 2.4 0.2 0.4 1.3 0.4 0.1 17.1 17.3 15.7 23.7 25.2 23.8 17.0 16.5 22.2 16.7 18.9 21.3 308.0 0.0 3.4 5.9 161.3 162.6 151.2 31.5 81.4 59.3 235.9 341.4 3.1 8.6 9.9 20.2 54.2 87.8 432.7 59.2 15.6 42.8 127.5 89.3 68.2 72.5 92.6 166.5 8.7 30.5 247.9 99.3 44.9 68.0 18.4 200.9 31.8 10.6 65.5 32.0 11.0 69.1 38.7 26.8 125.3 52.2 17.4 131.7 74.7 3.7 36.7 91.1 21.6 7.5 13.5 82.3 44.1 12.4 100.6 82.9 20.4 18.4 9.7 75.7 13.1 125.2 186.7 196.9 174.0 74.1 115.9 59.8 233.3 64.6 55.8 121.1 UBQLN2 "Chap1, CHAP1/DSK2, Dsk2, LIC-2, N4BP4, PLIC-2, PLIC2, RIHFB2157" ENSG00000188021 "Ubiquilin 2" Q9UHD9 X 56563627-56567868 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" Autophagy "Amyotrophic lateral sclerosis, Disease variant, Neurodegeneration" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006431, CAB013481" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB013481: AB_2533341, HPA006431: AB_1078707" "unprognostic (1.23e-2)" "unprognostic (2.88e-1)" "unprognostic (1.47e-1)" "unprognostic (1.51e-3)" "unprognostic (1.76e-2)" "unprognostic (5.08e-2)" "prognostic unfavorable (2.29e-4)" "unprognostic (2.66e-1)" "unprognostic (1.25e-1)" "unprognostic (4.42e-1)" "unprognostic (1.55e-1)" "unprognostic (1.13e-1)" "unprognostic (8.81e-2)" "unprognostic (1.35e-1)" "unprognostic (1.45e-1)" "unprognostic (8.88e-2)" "unprognostic (8.42e-3)" 13.8 20.2 24.9 14.9 26.8 11.1 12.1 19.7 30.6 15.9 12.7 15.7 11.2 16.6 15.9 18.7 17.5 14.5 21.6 27.4 25.5 13.5 19.4 13.8 18.4 20.2 20.4 25.7 10.5 23.6 16.3 15.8 22.1 20.2 12.1 22.2 14.4 20.0 28.0 13.6 12.4 18.4 21.3 14.9 13.1 4.4 22.6 18.9 20.7 22.8 18.6 18.6 11.1 25.5 36.3 26.5 25.9 30.6 58.3 37.0 16.3 28.6 33.9 21.0 23.2 14.9 16.6 27.6 30.5 34.0 32.9 20.7 50.0 31.9 25.3 43.0 30.1 11.2 34.2 15.9 30.6 22.1 23.7 34.7 39.6 28.3 24.6 30.3 18.7 17.6 13.3 29.5 33.6 16.9 28.5 19.2 21.7 11.6 31.1 25.3 33.7 26.3 42.8 27.9 31.9 29.9 41.3 18.1 17.4 45.2 30.4 16.1 21.2 22.2 22.5 32.4 17.5 11.1 14.8 18.9 24.9 23.1 19.3 50.0 23.6 24.1 15.1 31.1 17.1 7.8 22.9 17.7 17.8 8.6 30.3 18.9 20.4 20.9 34.2 6.5 23.5 20.3 24.9 26.8 19.7 30.6 27.4 25.5 20.2 20.4 22.1 21.3 22.6 25.5 13.9 22.4 17.2 0.0 30.5 31.2 41.6 27.4 20.5 42.3 14.5 11.3 37.6 15.7 25.0 18.4 18.8 28.8 15.4 12.1 17.6 20.0 0.1 11.8 22.7 18.9 34.2 18.3 0.0 16.6 26.7 27.9 13.7 15.7 12.7 14.2 18.2 20.3 24.7 42.1 0.0 20.3 18.3 30.7 25.3 1.6 24.8 21.1 17.8 0.0 35.9 22.3 42.2 0.0 0.0 18.9 12.7 36.5 23.5 32.0 20.7 16.4 27.5 35.8 13.1 25.4 29.8 0.3 1.5 32.7 30.4 40.0 28.7 12.2 19.3 35.6 UBR2 "bA49A4.1, C6orf133, dJ392M17.3, KIAA0349" ENSG00000024048 "Ubiquitin protein ligase E3 component n-recognin 2" Q8IWV8 6 42564029-42693505 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Ubl conjugation pathway" Transferase "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 138.5;Inhibitory neurons: 142.7" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "neutrophil: 38.5" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA027869, HPA027880" Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 21: OE19 - Mitochondria" "Cluster 6: Erythroid cells - Oxygen transport" Nucleoplasm "Plasma membrane" "HPA027869: AB_10600416, HPA027880: AB_10601217" "unprognostic (3.26e-1)" "unprognostic (1.29e-1)" "unprognostic (8.33e-2)" "unprognostic (2.95e-2)" "unprognostic (1.08e-2)" "unprognostic (4.23e-2)" "unprognostic (1.32e-1)" "unprognostic (7.24e-2)" "unprognostic (5.05e-2)" "prognostic favorable (1.65e-4)" "unprognostic (1.12e-1)" "unprognostic (7.53e-2)" "unprognostic (1.30e-2)" "unprognostic (3.88e-1)" "unprognostic (1.81e-1)" "unprognostic (5.78e-2)" "unprognostic (7.77e-3)" 11.0 10.7 8.5 12.7 10.1 17.9 12.9 14.1 11.1 10.3 11.3 12.7 14.4 10.9 11.2 9.5 9.4 8.6 11.2 9.0 8.8 12.1 17.2 11.9 12.7 9.0 8.7 12.2 15.6 15.0 8.8 11.7 9.3 10.5 13.8 29.7 12.0 10.0 22.8 12.2 13.8 10.6 8.6 15.3 12.2 6.2 9.1 13.5 13.3 22.3 11.5 10.8 10.4 14.2 18.5 9.0 10.4 16.4 20.9 20.0 14.0 13.8 14.9 12.0 12.4 13.2 7.4 12.5 10.7 15.0 13.9 18.1 15.1 11.8 15.2 17.1 10.6 20.0 13.3 17.3 17.0 19.6 13.1 14.1 12.7 12.0 12.9 14.8 13.7 17.9 23.7 15.4 11.7 14.9 15.4 17.1 9.5 36.2 8.7 13.6 15.5 19.0 13.8 15.7 12.4 9.8 14.0 13.3 13.9 15.7 13.0 18.7 19.8 10.8 8.4 13.5 10.1 14.1 13.4 18.9 5.7 14.5 6.8 17.7 7.1 15.2 6.5 7.3 5.4 5.2 4.2 5.1 5.5 5.2 4.3 4.8 38.5 5.9 9.8 4.1 5.3 3.4 8.5 10.1 14.1 11.1 9.0 8.8 9.0 8.7 9.3 8.6 9.1 14.2 33.5 16.0 24.6 82.6 33.9 16.6 18.1 14.9 28.5 43.0 20.4 15.9 39.3 30.0 22.1 20.2 60.5 17.4 46.6 51.6 17.6 18.5 12.4 27.5 30.8 24.8 12.6 75.1 138.5 15.3 13.4 26.5 34.1 32.9 20.3 31.3 21.8 35.0 13.2 63.9 142.7 22.5 14.2 26.7 28.6 3.9 25.4 26.1 19.6 87.1 43.0 23.5 32.0 123.1 131.4 15.0 29.1 24.0 50.6 22.8 37.2 11.7 27.9 53.5 39.5 30.0 27.2 11.2 10.9 28.1 16.2 17.2 44.0 24.0 21.5 22.7 ULBP1 RAET1I ENSG00000111981 "UL16 binding protein 1" Q9BZM6 6 149963943-149973715 "Predicted membrane proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 6 "brain: 4.4;lung: 1.7;testis: 3.3" "Cell type enhanced" "Detected in some" "Alveolar cells type 1: 6.4;Alveolar cells type 2: 2.2;Breast myoepithelial cells: 3.0;Respiratory ciliated cells: 2.2;Squamous epithelial cells: 2.5" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in some" 5 "cerebellum: 4.4;cerebral cortex: 1.9;hippocampal formation: 1.6" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "fHDF/TERT166: 16.5;HAP1: 29.3;HDLM-2: 17.1;HHSteC: 18.0;JURKAT: 26.1" "HPA007547, HPA071005" Enhanced Supported "Plasma membrane,Cytosol" NA NA "Cluster 78: Testis - Spermatogenesis" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 7: Non-specific - Mitochondria" "Plasma membrane, Cytosol" "HPA007547: AB_1079430, HPA071005: AB_2686332" "unprognostic (8.94e-3)" "unprognostic (2.44e-1)" "unprognostic (2.85e-2)" "unprognostic (2.33e-2)" "unprognostic (3.28e-4)" "unprognostic (6.69e-3)" "unprognostic (5.27e-2)" "unprognostic (2.47e-2)" "unprognostic (5.75e-2)" "unprognostic (1.31e-1)" "unprognostic (1.86e-1)" "unprognostic (1.15e-2)" "unprognostic (5.57e-12)" "unprognostic (1.95e-1)" "unprognostic (1.33e-1)" "unprognostic (1.12e-1)" "unprognostic (7.16e-2)" 0.2 0.1 0.1 0.2 0.1 0.3 0.0 4.4 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.4 1.6 0.2 0.4 0.1 1.7 0.1 0.1 0.2 0.0 0.1 0.2 0.1 0.5 0.5 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.0 0.0 3.3 0.1 0.1 0.4 0.1 0.1 0.0 0.0 0.2 2.1 1.0 1.6 0.0 3.3 6.8 3.2 3.0 0.9 0.6 2.0 0.2 3.1 3.5 0.7 16.5 6.9 0.7 29.3 1.4 2.7 17.1 3.8 0.3 0.6 0.0 18.0 0.1 1.2 9.1 6.8 13.6 2.5 0.0 1.1 26.1 3.3 0.0 3.5 2.7 4.3 0.0 0.5 1.4 2.3 0.0 1.3 0.5 0.0 0.4 1.0 0.4 4.4 2.0 0.0 1.3 2.9 6.4 0.3 1.6 0.0 1.4 0.0 0.5 0.7 2.3 8.7 5.0 3.6 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.1 4.4 1.9 1.6 0.2 0.1 0.2 0.5 0.1 0.1 0.2 1.6 6.4 2.2 0.0 0.5 0.1 0.5 0.0 0.6 0.0 1.0 3.0 0.9 0.0 0.6 0.0 0.0 0.0 0.3 0.4 0.0 0.3 0.1 0.2 0.6 1.1 0.0 0.0 0.1 0.6 0.0 1.6 0.0 0.7 0.0 0.1 0.7 0.0 0.1 0.0 0.0 0.5 0.0 0.3 0.3 0.4 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.2 0.0 0.1 2.2 0.0 0.0 1.6 1.3 0.2 0.2 2.5 0.6 0.0 0.7 0.2 0.3 0.1 ULBP2 RAET1H ENSG00000131015 "UL16 binding protein 2" Q9BZM5 6 149942014-149949235 "Predicted membrane proteins, Predicted secreted proteins" "Host-virus interaction, Immunity" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "esophagus: 6.1" "Cell type enhanced" "Detected in many" "Adipocytes: 28.9;Basal respiratory cells: 17.9;dendritic cells: 12.1" "Cancer enhanced" "Detected in all" "head and neck cancer: 12.9" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in some" "gdT-cell: 2.7" "Lineage enriched" "Detected in single" 6 "T-cells: 2.7" "Cell line enhanced" "Detected in many" "SiHa: 66.7;U-2197: 47.4" "CAB018974, HPA066741" Approved Supported "Vesicles,Plasma membrane" "Secreted in other tissues" NA NA "Cluster 20: T-cells - T-cell receptor" "Cluster 27: Brain & Skin - Unknown function" "Cluster 18: U-2197 - ECM organization" "Cluster 7: Non-specific - Mitochondria" "Vesicles, Plasma membrane" "CAB018974: , HPA066741: " "unprognostic (2.09e-5)" "prognostic unfavorable (8.07e-4)" "unprognostic (2.38e-3)" "unprognostic (3.90e-1)" "prognostic unfavorable (2.44e-4)" "unprognostic (1.26e-2)" "unprognostic (2.38e-3)" "unprognostic (1.47e-1)" "unprognostic (1.02e-1)" "unprognostic (1.05e-1)" "unprognostic (1.99e-1)" "unprognostic (1.75e-2)" "unprognostic (1.42e-4)" "unprognostic (1.68e-1)" "unprognostic (2.06e-1)" "unprognostic (2.14e-1)" "unprognostic (4.86e-1)" 1.5 0.7 1.3 0.6 1.6 1.8 0.7 1.6 2.6 0.9 0.7 0.2 0.2 0.1 0.1 6.1 0.2 0.5 2.0 3.0 1.0 2.1 0.5 3.4 0.3 1.8 1.2 0.0 0.4 0.6 0.5 1.6 1.8 0.2 0.1 0.2 0.7 0.1 0.3 0.5 0.2 0.7 0.8 0.2 0.3 1.5 1.1 0.7 1.2 0.7 0.8 1.4 1.6 1.7 19.9 1.8 0.5 6.1 1.1 5.6 3.3 20.1 11.8 20.6 16.8 7.4 11.0 0.0 29.9 23.0 29.6 13.9 7.6 18.4 11.8 9.1 3.9 1.1 2.8 0.0 7.1 0.0 1.5 2.7 13.9 18.3 8.0 16.7 11.9 16.6 2.5 0.0 15.4 13.9 1.8 0.0 0.0 3.6 10.2 3.0 4.5 0.0 29.0 5.7 0.6 0.0 66.7 1.4 1.9 3.2 1.8 8.5 18.8 13.5 17.1 47.4 23.5 0.0 0.1 0.9 19.2 10.7 9.9 0.0 0.0 0.0 2.7 0.0 0.3 0.0 0.8 1.5 0.0 0.0 0.3 1.8 0.0 0.4 0.0 0.0 1.7 0.5 1.3 1.6 1.6 2.6 3.0 1.0 1.8 1.2 1.8 0.8 1.1 1.7 28.9 0.0 1.3 0.0 1.2 3.7 6.5 17.9 7.4 0.0 1.3 4.4 0.3 0.0 9.4 1.8 0.0 0.0 12.1 0.5 0.0 7.5 7.0 0.3 0.5 9.1 0.0 0.0 3.0 8.8 0.5 3.0 1.1 0.2 0.0 0.1 7.1 0.2 2.2 0.0 0.7 0.3 2.0 0.8 2.1 8.0 0.0 3.1 1.8 0.0 0.0 0.4 4.1 0.5 0.3 4.5 0.0 0.0 1.4 1.4 0.0 0.1 1.4 0.0 0.0 1.0 4.2 3.1 7.0 11.8 2.8 0.0 11.0 0.6 0.4 5.2 UNC5A "KIAA1976, UNC5H1" ENSG00000113763 "Unc-5 netrin receptor A" Q6ZN44 5 176810519-176880898 "Predicted membrane proteins" Apoptosis "Developmental protein, Receptor" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 30.4;pituitary gland: 14.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 54.4;Inhibitory neurons: 19.4;Muller glia cells: 13.9" "Cancer enhanced" "Detected in many" "ovarian cancer: 7.5" "Group enriched" "Detected in many" 6 "amygdala: 10.5;basal ganglia: 15.1;cerebral cortex: 30.4;hippocampal formation: 16.3;white matter: 11.9" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enriched" "Detected in some" 8 "SCLC-21H: 86.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071450 Approved "Plasma membrane,Cytosol" NA NA "Cluster 2: Granulocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane, Cytosol" "HPA071450: AB_2686397" "unprognostic (5.95e-2)" "unprognostic (1.15e-1)" "unprognostic (4.18e-3)" "prognostic unfavorable (2.23e-4)" "unprognostic (5.26e-2)" "unprognostic (2.23e-1)" "unprognostic (6.66e-3)" "unprognostic (5.06e-3)" "unprognostic (3.52e-1)" "unprognostic (1.36e-1)" "unprognostic (5.07e-1)" "unprognostic (9.95e-2)" "unprognostic (3.77e-5)" "unprognostic (6.39e-2)" "unprognostic (2.89e-1)" "unprognostic (2.27e-1)" "unprognostic (5.17e-2)" 0.4 7.5 10.5 0.3 15.1 0.4 0.7 2.6 30.4 0.3 0.0 0.1 0.4 0.4 0.2 0.1 0.6 0.2 0.3 16.3 0.0 0.1 0.1 0.3 0.9 0.0 0.0 0.1 1.8 0.0 14.7 0.0 0.0 0.2 0.0 3.1 2.5 0.0 0.0 0.5 0.1 0.1 0.0 0.1 1.0 0.7 0.0 0.1 0.5 0.0 0.0 0.2 0.1 11.9 0.0 0.1 0.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 5.7 0.0 0.1 0.0 5.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 2.3 0.0 0.0 1.4 3.5 0.0 0.0 0.0 2.5 10.1 0.0 86.4 3.9 0.0 0.3 0.0 0.0 0.3 0.3 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.9 0.0 0.8 0.0 0.3 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 10.5 15.1 2.6 30.4 16.3 0.0 0.0 0.0 0.0 0.0 0.0 11.9 0.3 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 4.7 0.6 0.3 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.9 0.1 0.9 0.0 0.0 54.4 0.0 0.0 0.0 0.0 1.6 0.0 2.0 0.0 0.0 0.0 5.0 19.4 0.0 0.0 0.0 0.0 3.2 0.0 0.0 0.0 4.7 0.0 13.9 0.0 7.1 2.1 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.5 0.0 0.0 0.0 0.1 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 UNC79 KIAA1409 ENSG00000133958 "Unc-79 homolog, NALCN channel complex subunit" Q9P2D8 14 93333219-93707876 "Predicted membrane proteins, Transporters" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "brain: 5.1;pituitary gland: 11.7" "Group enriched" "Detected in some" 4 "Excitatory neurons: 524.0;Inhibitory neurons: 463.6;Oligodendrocyte precursor cells: 270.4;Oligodendrocytes: 202.6" "Cancer enhanced" "Detected in some" "glioma: 0.7" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Group enriched" "Detected in some" 5 "REH: 4.3;SCLC-21H: 3.0;SH-SY5Y: 1.9;U-937: 1.5" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA071881 Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 58: Brain - Synaptic function" "Cluster 7: SCLC-21H - Neuronal signaling" "Cluster 21: Neurons & Oligodendrocytes - Neuronal signaling" "Plasma membrane" Nucleoplasm "HPA071881: AB_2732189" "unprognostic (8.42e-2)" "unprognostic (2.07e-1)" "unprognostic (6.70e-2)" "unprognostic (6.91e-2)" "unprognostic (1.06e-1)" "unprognostic (7.73e-2)" "unprognostic (2.99e-2)" "unprognostic (1.17e-1)" "unprognostic (2.31e-1)" "unprognostic (5.73e-3)" "unprognostic (8.03e-3)" "unprognostic (2.87e-1)" "unprognostic (3.39e-2)" "unprognostic (2.66e-2)" "unprognostic (5.57e-2)" "unprognostic (3.03e-2)" "unprognostic (7.47e-2)" 0.0 0.7 2.2 0.0 2.8 0.0 0.0 5.1 4.7 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.2 0.0 0.1 2.1 1.9 0.3 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.2 11.7 0.0 0.0 0.0 0.0 3.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.3 2.5 0.4 0.0 0.1 0.3 0.0 0.0 0.0 2.3 0.0 0.0 0.0 0.0 0.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.5 0.0 0.0 4.3 0.0 0.0 0.1 0.1 3.0 1.9 0.0 0.0 0.0 0.1 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 2.2 2.8 5.1 4.7 2.1 1.9 0.0 0.1 0.0 0.0 0.4 2.3 0.3 0.0 0.0 89.8 0.4 0.3 0.3 0.5 0.0 41.9 0.3 0.3 2.8 0.0 0.1 0.0 10.4 0.1 0.3 0.7 0.0 0.3 36.9 4.8 0.9 0.6 0.0 0.4 524.0 0.2 0.1 0.6 1.1 0.8 0.0 0.3 0.4 0.2 0.3 40.4 463.6 0.3 0.0 0.6 0.4 16.4 0.6 0.4 0.0 23.4 0.1 2.1 0.0 270.4 202.6 0.4 0.1 0.4 0.0 0.3 0.6 1.9 0.9 5.7 0.0 0.5 0.8 3.4 2.5 0.2 0.3 0.7 0.2 0.5 0.2 0.3 USP14 TGT ENSG00000101557 "Ubiquitin specific peptidase 14" P54578 18 158383-214629 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Immunity, Innate immunity, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA001308 Approved Supported "Plasma membrane,Cytosol" NA NA 2700000 "Cluster 15: NK-cells - Transcription" "Cluster 39: Non-specific - Mitochondria" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 39: Non-specific - Basic cellular processes" "Plasma membrane, Cytosol" "HPA001308: AB_1080499" "unprognostic (2.21e-1)" "unprognostic (4.05e-2)" "unprognostic (1.90e-1)" "unprognostic (2.59e-3)" "unprognostic (6.04e-2)" "prognostic unfavorable (7.81e-5)" "prognostic unfavorable (4.30e-5)" "unprognostic (5.14e-2)" "unprognostic (5.00e-2)" "prognostic favorable (7.91e-4)" "unprognostic (1.64e-2)" "unprognostic (2.39e-1)" "unprognostic (1.51e-3)" "unprognostic (2.58e-1)" "unprognostic (1.55e-1)" "unprognostic (2.20e-2)" "unprognostic (3.76e-2)" 26.0 21.5 19.9 22.7 21.3 23.9 17.0 20.1 22.9 15.5 13.9 17.8 13.9 17.0 23.8 24.0 14.6 14.6 24.8 21.0 24.5 23.4 25.3 15.1 21.6 25.4 21.7 13.3 13.0 21.2 14.3 26.5 25.7 29.7 19.3 15.5 15.2 19.6 55.6 15.4 12.4 24.7 20.3 13.8 15.1 17.9 26.0 21.8 20.4 36.4 31.3 22.6 15.3 23.3 91.6 75.4 62.7 64.5 60.7 60.0 109.6 115.5 64.9 118.9 110.5 98.9 48.7 133.1 86.6 99.1 114.4 50.9 125.1 91.7 134.9 38.7 59.0 72.5 46.0 78.1 60.5 184.1 70.8 48.4 69.1 122.3 69.5 55.0 93.5 65.9 106.2 99.3 119.1 76.2 105.2 52.4 59.4 56.0 83.5 87.8 78.6 98.0 88.7 79.9 71.8 60.1 120.7 59.2 52.5 68.0 58.2 51.5 103.9 138.7 104.3 128.8 170.6 62.3 125.7 130.9 80.0 77.3 88.4 10.7 18.1 13.8 27.9 25.8 33.6 21.1 27.5 29.5 25.6 16.4 26.7 26.2 1.5 39.3 20.5 18.7 28.6 19.4 19.9 21.3 20.1 22.9 21.0 24.5 25.4 21.7 25.7 20.3 26.0 23.3 40.0 22.4 40.4 27.7 52.7 58.6 53.3 42.0 51.8 58.0 33.4 23.5 44.9 31.5 48.3 44.1 31.3 92.3 58.1 22.5 45.0 60.6 70.9 44.9 56.3 43.1 22.1 102.0 58.8 54.0 71.8 49.0 43.8 80.8 34.8 47.1 28.2 45.4 50.9 116.1 54.4 22.5 46.8 31.5 53.4 21.6 31.7 45.5 35.6 33.7 48.8 39.4 46.4 35.2 74.8 75.8 16.9 45.9 72.7 71.4 15.2 56.0 40.2 50.3 0.0 49.6 51.4 34.1 68.1 57.9 52.4 135.6 55.0 58.9 33.5 51.8 USP2 UBP41 ENSG00000036672 "Ubiquitin specific peptidase 2" O75604 11 119355215-119381711 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Biological rhythms, Cell cycle, Myogenesis, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "skeletal muscle: 168.3" "Group enriched" "Detected in many" 5 "Early spermatids: 460.0;Late spermatids: 1094.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "K-562: 14.5;U-266/70: 56.9" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA006777, HPA007222" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 54: Non-specific - Microtubule organization" "Cluster 29: U-266 - Adaptive immune response" "Cluster 31: Spermatids - Spermatogenesis" Cytosol "Plasma membrane" "HPA006777: AB_1080507, HPA007222: AB_1080505" "unprognostic (6.83e-2)" "unprognostic (2.02e-2)" "unprognostic (5.54e-2)" "unprognostic (1.37e-2)" "unprognostic (1.25e-1)" "unprognostic (7.46e-3)" "unprognostic (1.00e-1)" "unprognostic (5.27e-2)" "unprognostic (1.24e-1)" "unprognostic (5.24e-3)" "unprognostic (8.02e-3)" "unprognostic (7.33e-2)" "prognostic favorable (3.09e-11)" "unprognostic (1.58e-1)" "unprognostic (1.20e-1)" "unprognostic (1.96e-2)" "unprognostic (2.66e-2)" 7.0 13.4 11.9 1.6 22.6 1.9 4.1 18.8 19.0 6.0 32.7 10.2 13.9 5.2 5.7 9.8 11.6 2.3 73.5 18.6 9.4 53.4 18.9 3.4 0.1 12.0 13.1 6.2 18.1 24.2 18.9 1.3 7.7 4.1 6.0 76.2 7.6 3.0 168.3 12.8 17.4 6.8 8.2 0.6 6.2 86.5 15.1 0.6 3.8 62.8 0.6 4.5 4.8 17.5 6.0 0.5 0.9 3.2 0.1 0.2 1.3 0.7 0.4 0.0 0.6 6.1 0.8 10.2 1.8 1.1 1.4 1.0 7.9 2.9 0.2 7.2 1.0 2.8 4.4 12.5 2.7 0.0 2.8 0.9 0.6 0.7 2.0 1.3 0.6 7.6 14.5 0.8 1.7 4.1 0.0 0.6 1.6 2.0 1.3 0.1 2.1 1.5 4.6 0.3 11.9 3.6 3.4 2.6 0.7 1.7 8.8 6.2 0.0 0.0 1.5 0.8 1.0 56.9 13.5 0.2 0.1 2.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 11.9 22.6 18.8 19.0 18.6 9.4 12.0 13.1 7.7 8.2 15.1 17.5 0.6 3.2 2.7 10.7 0.6 2.4 5.3 1.5 1.2 75.2 3.3 2.4 85.2 7.2 6.1 5.5 95.9 0.5 1.6 25.5 113.5 3.1 460.0 39.0 3.0 3.6 0.0 0.4 15.7 1.6 0.9 7.4 2.0 8.4 0.0 2.0 2.2 23.0 17.2 10.1 11.6 2.0 0.0 1.3 2.9 1094.1 6.5 2.1 0.0 1.9 0.0 49.7 0.0 8.0 12.5 1.2 11.8 7.2 0.1 1.1 41.3 41.6 35.0 140.0 19.7 43.3 24.0 50.5 16.5 12.9 4.0 1.4 1.3 0.5 2.6 2.9 USP4 "UNP, Unph" ENSG00000114316 "Ubiquitin specific peptidase 4" Q13107 3 49277144-49340712 "Enzymes, Metabolic proteins, Predicted intracellular proteins" "Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" Proto-oncogene "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Early spermatids: 131.8;Late spermatids: 104.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA018499 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 30: Epithelial cell lines - Translation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cytosol" "HPA018499: AB_1858689" "unprognostic (2.34e-3)" "unprognostic (1.52e-1)" "unprognostic (2.22e-3)" "unprognostic (6.12e-2)" "unprognostic (3.51e-1)" "unprognostic (4.33e-2)" "unprognostic (9.42e-2)" "prognostic favorable (4.46e-5)" "unprognostic (3.54e-1)" "unprognostic (9.07e-3)" "unprognostic (2.78e-2)" "unprognostic (1.70e-3)" "prognostic favorable (4.29e-5)" "unprognostic (7.30e-2)" "unprognostic (1.00e-1)" "unprognostic (1.18e-2)" "unprognostic (1.65e-2)" 25.2 20.3 24.2 26.5 26.3 53.7 24.9 24.5 28.2 27.7 27.1 25.4 18.3 24.4 21.6 26.0 22.4 18.3 26.5 23.7 23.4 21.8 20.2 29.5 30.9 23.9 24.4 24.5 19.0 24.1 16.4 23.3 23.9 23.7 23.4 26.9 21.0 21.7 31.6 31.4 22.5 24.0 22.4 33.7 20.2 28.0 24.8 37.0 23.0 28.8 33.7 25.8 25.0 24.5 14.2 15.8 21.6 28.8 38.7 40.1 14.7 36.4 32.9 46.7 41.3 16.8 34.8 27.1 14.4 53.9 27.4 18.9 28.6 52.6 42.5 42.1 8.4 60.3 31.9 19.6 57.0 32.5 34.0 42.8 23.3 51.0 41.5 34.3 55.0 29.9 21.6 41.6 42.1 24.5 38.3 55.8 18.7 17.7 26.9 15.6 13.3 23.9 37.5 29.2 17.5 24.0 27.2 19.3 14.0 21.6 13.5 51.2 50.1 31.1 17.2 39.6 22.5 33.6 17.3 38.6 28.6 50.1 36.5 70.1 83.6 94.8 48.1 69.2 53.7 51.0 50.2 48.9 74.6 41.4 47.7 42.2 179.2 72.4 81.2 28.4 59.7 78.0 24.2 26.3 24.5 28.2 23.7 23.4 23.9 24.4 23.9 22.4 24.8 24.5 24.3 41.7 25.1 28.1 24.7 18.7 17.9 17.2 22.2 17.5 10.9 10.3 17.9 10.0 23.2 20.2 20.9 22.7 27.9 13.6 21.5 16.5 131.8 17.3 18.3 22.1 10.7 31.6 30.8 13.6 14.3 17.9 27.5 21.1 33.6 21.4 17.5 14.6 24.0 11.8 26.4 13.8 16.2 38.6 21.0 104.9 15.5 34.2 16.0 16.9 36.0 13.9 23.7 25.6 20.2 18.9 7.6 19.2 29.2 17.6 14.5 13.4 28.6 20.5 13.1 18.4 17.0 35.3 14.5 17.9 18.5 24.2 29.4 17.0 13.9 14.5 USP53 KIAA1350 ENSG00000145390 "Ubiquitin specific peptidase 53" Q70EK8 4 119212587-119295517 "Enzymes, Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in all" "Glandular and luminal cells: 586.8;Microglial cells: 269.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Cell line enhanced" "Detected in many" "BJ hTERT+: 327.9;SK-MEL-30: 102.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035844, HPA035845" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 32: T-cells - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 44: Endometrium - Transcription" "Plasma membrane, Cytosol" "HPA035844: AB_10669532, HPA035845: AB_2674817" "unprognostic (9.33e-2)" "unprognostic (1.49e-2)" "prognostic favorable (3.15e-6)" "unprognostic (4.37e-3)" "unprognostic (4.82e-2)" "unprognostic (5.03e-2)" "unprognostic (1.55e-1)" "unprognostic (9.54e-2)" "unprognostic (1.77e-1)" "unprognostic (9.81e-3)" "unprognostic (1.28e-1)" "prognostic unfavorable (7.54e-6)" "prognostic favorable (3.58e-8)" "unprognostic (9.02e-2)" "unprognostic (1.72e-1)" "unprognostic (1.58e-1)" "unprognostic (3.70e-2)" 37.8 14.4 5.6 5.7 5.8 0.9 25.3 6.1 6.2 18.5 11.8 16.3 5.7 13.1 13.1 17.0 30.6 10.2 24.0 4.9 7.3 19.9 7.3 29.4 12.4 9.4 8.1 9.4 24.6 8.1 10.3 10.5 7.3 9.2 16.1 3.4 12.7 11.5 33.5 11.7 9.7 10.2 6.5 7.2 15.1 7.8 8.6 5.4 10.5 51.7 8.0 12.7 12.0 5.5 11.4 6.8 2.4 0.0 60.5 60.4 13.6 70.6 327.9 6.2 8.1 7.4 10.4 46.1 2.5 21.1 12.1 5.5 5.5 5.3 16.1 6.1 4.5 3.1 5.2 2.6 47.2 3.9 0.7 20.3 15.0 21.9 31.0 11.7 29.8 3.0 7.3 1.7 8.4 2.5 2.9 5.2 6.7 7.0 3.8 0.9 11.4 9.2 16.4 7.2 3.8 3.0 3.9 27.5 102.4 13.3 7.0 2.7 32.3 2.0 7.0 26.3 6.4 3.3 5.2 7.8 31.4 1.7 7.9 1.3 0.0 0.0 0.4 0.0 0.5 0.7 1.0 0.8 0.1 0.7 1.9 1.0 0.2 0.9 0.0 0.3 0.9 0.3 5.6 5.8 6.1 6.2 4.9 7.3 9.4 8.1 7.3 6.5 8.6 5.5 27.6 35.3 44.5 80.6 18.5 61.8 73.6 21.2 48.3 17.8 74.1 46.6 99.0 32.9 33.9 119.5 29.2 48.4 15.1 207.8 45.0 33.4 5.6 167.2 45.9 35.7 34.6 4.8 32.4 62.7 17.3 86.0 41.8 586.8 70.8 19.8 23.9 30.5 9.3 25.2 32.5 80.4 52.9 21.3 76.4 7.3 19.0 36.5 14.2 269.8 45.6 25.0 12.3 11.6 11.9 110.6 214.5 10.9 18.6 138.6 46.0 20.1 27.3 31.5 6.6 91.8 32.9 18.0 4.0 62.6 42.3 49.8 26.8 14.8 62.6 124.8 UTP20 "1A6/DRIM, DRIM" ENSG00000120800 "UTP20 small subunit processome component" O75691 12 101280105-101386618 "Predicted intracellular proteins" "rRNA processing" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049341 Supported "Nucleoli,Plasma membrane" No No "Cluster 29: Plasmacytoid DCs - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 59: Non-specific - Transcription" Nucleoli "Plasma membrane" "HPA049341: AB_2680720" "unprognostic (3.04e-2)" "unprognostic (1.22e-1)" "unprognostic (3.92e-2)" "unprognostic (1.51e-2)" "unprognostic (1.39e-1)" "unprognostic (1.15e-1)" "prognostic unfavorable (1.15e-5)" "unprognostic (8.34e-2)" "unprognostic (4.30e-2)" "unprognostic (8.15e-3)" "unprognostic (2.81e-1)" "unprognostic (2.22e-2)" "prognostic favorable (8.87e-4)" "unprognostic (2.88e-1)" "unprognostic (3.44e-1)" "unprognostic (8.30e-2)" "unprognostic (6.92e-3)" 4.3 4.2 2.2 5.0 3.7 4.2 5.7 2.9 2.7 5.7 2.5 3.2 2.1 4.6 2.6 4.0 3.8 2.4 3.0 2.3 2.5 3.3 3.0 3.0 5.0 2.8 2.8 6.4 4.8 5.3 2.2 4.3 2.9 3.5 4.2 3.5 5.6 3.3 5.2 4.6 3.1 4.0 2.4 3.6 3.2 5.6 3.3 4.3 4.2 3.9 4.8 5.1 3.5 5.0 8.1 19.9 14.8 6.9 13.0 15.1 18.2 13.8 10.8 21.5 11.8 23.1 5.7 21.6 7.1 15.4 16.2 16.6 33.0 14.2 27.8 9.8 13.4 22.8 10.0 17.3 7.3 38.4 10.2 9.9 7.3 29.9 10.3 8.2 15.0 10.9 36.7 4.3 15.8 10.6 16.8 10.9 38.9 11.3 20.6 18.8 24.2 16.8 9.1 24.4 17.0 11.5 25.8 16.1 15.7 12.2 17.0 8.5 17.1 25.3 12.5 17.8 27.1 7.8 12.6 35.1 13.8 17.2 39.6 0.0 0.2 0.0 0.5 0.3 0.5 0.9 0.5 0.7 0.4 0.6 0.6 0.7 0.0 0.6 0.2 0.8 0.5 0.2 2.2 3.7 2.9 2.7 2.3 2.5 2.8 2.8 2.9 2.4 3.3 5.0 14.3 9.6 9.9 16.0 16.7 10.1 9.7 7.7 11.4 9.9 8.7 8.4 10.3 7.2 13.6 3.7 10.4 7.8 4.4 3.4 5.9 7.6 1.5 11.4 24.5 12.6 6.6 14.9 17.0 11.6 8.8 13.0 7.7 10.1 13.3 18.6 7.1 7.6 5.8 21.9 17.0 6.3 4.1 6.3 3.5 1.2 9.6 8.6 3.6 8.4 3.3 3.3 4.1 16.1 34.2 5.9 1.9 8.2 13.2 14.5 1.1 3.0 9.0 9.4 6.6 24.9 11.0 22.6 22.3 17.3 11.1 2.9 10.0 23.7 9.8 7.2 UTRN "DMDL, DRP, DRP1" ENSG00000152818 Utrophin P46939 6 144285701-144853034 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Alveolar cells type 1: 410.3;Early spermatids: 527.1;Late spermatids: 332.1;Microglial cells: 425.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HAP1: 219.4;HUVEC TERT2: 157.0;TIME: 203.6" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB016348, HPA018894" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA 4200 "Cluster 51: Monocytes - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "CAB016348: AB_628424, HPA018894: AB_10600839" "unprognostic (3.47e-2)" "unprognostic (2.82e-1)" "unprognostic (2.32e-1)" "unprognostic (6.87e-3)" "unprognostic (1.75e-1)" "unprognostic (3.30e-2)" "unprognostic (3.99e-3)" "unprognostic (2.44e-1)" "unprognostic (9.24e-2)" "unprognostic (1.29e-1)" "unprognostic (2.72e-1)" "unprognostic (7.10e-2)" "prognostic favorable (7.61e-5)" "unprognostic (6.32e-2)" "unprognostic (2.20e-1)" "unprognostic (1.66e-1)" "unprognostic (1.49e-2)" 52.6 17.4 26.8 25.8 40.5 56.6 40.5 32.7 18.3 40.4 35.6 33.8 17.0 29.8 16.8 27.9 43.5 31.2 24.8 18.4 67.9 30.9 25.3 49.3 34.9 48.6 52.1 37.2 52.1 69.4 7.9 45.8 49.7 39.7 31.7 11.0 26.0 26.1 14.0 27.5 22.3 25.9 40.0 71.5 27.2 59.2 48.8 43.2 68.4 38.9 35.8 25.2 16.0 31.0 27.2 22.6 39.3 51.0 66.5 60.5 23.4 39.0 37.8 31.1 45.2 86.1 9.8 8.4 33.6 88.4 36.6 15.6 219.4 32.9 44.6 90.6 25.5 32.2 24.9 51.6 26.3 36.1 0.7 35.5 6.8 46.2 24.1 29.3 157.0 25.1 2.0 22.7 44.1 18.1 28.7 15.5 15.9 16.6 23.9 25.7 70.2 0.8 35.9 0.7 49.7 0.9 60.8 8.4 23.5 59.5 33.3 48.2 203.6 29.8 37.0 15.5 37.6 17.7 25.3 1.3 18.2 21.5 49.5 41.2 40.9 23.2 39.5 120.8 28.3 25.7 24.9 33.0 17.2 35.7 21.8 22.8 34.5 37.6 173.9 50.4 22.2 13.9 26.8 40.5 32.7 18.3 18.4 67.9 48.6 52.1 49.7 40.0 48.8 31.0 267.0 410.3 138.7 148.2 101.2 29.4 31.7 17.2 40.9 6.5 47.4 32.1 56.0 28.6 111.0 31.3 0.0 94.4 175.1 10.9 0.0 25.3 527.1 61.2 51.5 171.8 31.2 19.8 61.2 32.0 6.9 51.6 76.5 87.5 29.7 22.8 83.6 15.6 22.3 60.6 161.4 16.9 8.2 109.7 45.9 332.1 23.9 97.6 39.2 425.3 79.8 29.1 171.0 68.9 4.1 28.1 9.3 33.4 70.3 25.4 3.6 7.1 87.3 4.3 144.7 151.0 157.8 6.6 6.6 33.7 45.5 129.3 108.0 32.0 22.3 19.2 VAMP5 ENSG00000168899 "Vesicle associated membrane protein 5" O95183 2 85584431-85593406 "Predicted membrane proteins" "Differentiation, Myogenesis" "Developmental protein" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Adipocytes: 487.9;Endothelial cells: 337.8;Hepatic stellate cells: 486.2;Kupffer cells: 340.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "HUVEC TERT2: 364.7;LHCN-M2: 428.9;TIME: 250.0" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA035082 Supported Approved "Nucleoplasm,Plasma membrane" NA NA 130000 "Cluster 7: Monocytes - Unknown function" "Cluster 80: Striated muscle - Unknown function" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Nucleoplasm, Plasma membrane" "HPA035082: AB_10610564" "unprognostic (1.92e-1)" "unprognostic (3.09e-2)" "unprognostic (6.09e-2)" "unprognostic (1.13e-2)" "unprognostic (4.16e-2)" "unprognostic (1.25e-3)" "unprognostic (1.28e-2)" "unprognostic (5.29e-2)" "unprognostic (1.17e-2)" "unprognostic (3.49e-2)" "unprognostic (2.22e-1)" "unprognostic (7.59e-2)" "prognostic unfavorable (1.28e-5)" "unprognostic (9.61e-3)" "unprognostic (3.46e-2)" "unprognostic (1.71e-2)" "unprognostic (2.60e-1)" 134.0 117.4 71.0 59.9 74.1 41.2 118.4 72.9 89.1 78.6 66.8 76.4 23.3 79.4 33.2 45.3 84.3 58.0 114.7 69.4 76.1 90.0 79.3 134.6 92.7 79.1 71.4 52.8 29.0 14.7 31.9 74.1 74.2 72.8 20.5 2.9 36.9 36.7 217.3 44.5 54.1 77.2 73.8 97.5 54.0 11.4 78.0 50.9 63.8 199.6 41.2 87.1 69.7 71.7 0.8 0.2 2.4 0.0 89.3 155.8 2.4 98.5 155.9 95.5 104.5 39.5 15.1 0.3 2.3 172.2 50.7 1.1 0.0 2.4 42.2 142.9 2.8 1.9 2.5 56.1 187.2 4.5 0.9 108.4 9.6 40.1 1.1 138.9 364.7 61.7 0.4 0.3 428.9 14.5 63.1 13.8 0.1 27.2 0.6 92.4 0.4 2.7 2.7 3.6 0.2 3.4 0.6 27.4 0.5 2.2 3.2 5.1 250.0 2.3 6.7 7.5 0.2 0.1 3.1 2.4 110.5 5.4 65.9 59.1 222.6 176.5 180.5 503.8 171.7 60.7 136.1 135.2 79.0 54.5 102.4 125.1 70.2 94.4 424.9 86.4 248.7 283.0 71.0 74.1 72.9 89.1 69.4 76.1 79.1 71.4 74.2 73.8 78.0 71.7 487.9 19.2 21.2 3.6 43.9 60.8 39.8 104.1 39.3 0.8 14.9 27.3 84.4 71.4 70.1 44.1 0.0 22.9 64.5 38.8 29.4 29.9 1.8 7.7 64.7 337.8 12.6 35.6 0.1 49.1 7.2 148.0 9.7 7.9 44.4 22.2 486.2 198.6 80.3 3.3 0.2 20.5 36.7 340.8 91.5 10.2 192.6 147.8 275.7 4.7 136.0 17.5 112.3 0.5 1.6 44.2 51.9 165.1 68.4 64.7 126.5 91.2 50.6 1.0 59.2 152.2 83.9 5.5 6.6 19.8 45.3 21.6 88.5 19.2 7.8 49.4 VCPIP1 "DUBA3, FLJ23132, KIAA1850, VCIP135" ENSG00000175073 "Valosin containing protein interacting protein 1" Q96JH7 8 66628487-66667231 "Enzymes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Ubl conjugation pathway" "Hydrolase, Protease, Thiol protease" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "bone marrow: 20.2" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA023932 Uncertain Approved "Plasma membrane,Centrosome" NA NA "Cluster 18: Basophils - Vesicular transport" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 3: HMC-1 - Innate immune response" "Cluster 10: Non-specific - Unknown function" "Plasma membrane" Centrosome "HPA023932: AB_2671373" "unprognostic (1.12e-1)" "unprognostic (1.31e-2)" "unprognostic (9.13e-2)" "unprognostic (1.10e-2)" "unprognostic (4.01e-2)" "unprognostic (5.56e-2)" "unprognostic (5.23e-2)" "unprognostic (7.21e-2)" "unprognostic (2.80e-1)" "unprognostic (3.96e-1)" "unprognostic (5.23e-3)" "unprognostic (7.28e-2)" "unprognostic (6.12e-3)" "unprognostic (2.03e-2)" "unprognostic (1.83e-1)" "unprognostic (2.13e-2)" "unprognostic (8.58e-3)" 4.6 3.6 3.2 6.0 3.6 20.2 4.8 4.1 5.1 3.7 1.8 4.4 3.8 3.0 4.5 3.5 2.9 3.7 2.9 4.1 4.7 4.4 7.0 4.1 8.6 4.0 3.6 3.9 4.0 5.6 1.6 4.4 4.4 3.6 4.1 4.5 4.2 3.1 5.3 3.3 3.6 3.3 3.4 8.8 4.5 5.7 5.0 5.3 4.2 5.3 7.7 4.1 2.4 4.3 8.5 7.6 3.8 5.1 11.5 8.1 3.7 6.7 6.7 5.0 5.8 4.5 7.8 11.5 1.9 9.0 6.2 7.4 6.2 5.6 7.2 8.6 4.5 12.8 7.5 5.6 6.9 4.3 13.2 8.7 8.1 5.5 9.9 6.1 5.5 6.1 8.8 10.8 7.5 4.1 9.4 7.4 7.3 7.1 5.2 5.9 6.0 5.8 7.3 6.6 2.2 4.3 5.2 7.8 6.0 4.8 8.0 7.0 11.1 6.6 4.9 5.9 4.5 9.5 5.0 11.9 6.6 6.0 5.1 10.0 2.7 5.9 3.4 4.3 2.8 1.7 2.1 2.5 2.9 2.2 1.7 2.2 9.7 2.4 8.3 1.1 2.8 1.7 3.2 3.6 4.1 5.1 4.1 4.7 4.0 3.6 4.4 3.4 5.0 4.3 18.6 19.2 15.2 9.8 18.5 17.0 9.3 10.3 12.5 11.0 12.6 9.4 20.3 11.5 12.8 7.3 22.9 10.4 38.9 18.4 3.9 10.2 7.5 16.7 17.1 14.2 6.0 23.4 17.6 13.6 5.5 15.0 15.3 16.4 19.0 12.4 17.2 22.9 14.9 11.8 18.1 15.5 8.2 47.3 20.4 5.2 8.1 25.6 10.6 14.0 28.6 11.9 39.1 13.6 21.1 13.0 16.6 15.8 21.8 14.2 14.7 12.8 18.6 12.1 6.6 21.7 20.2 32.9 16.6 16.3 20.6 9.9 28.6 11.8 13.2 16.9 VPS50 "CCDC132, DKFZp313I2429, FLJ20097, KIAA1861, VPS54L" ENSG00000004766 "VPS50 subunit of EARP/GARPII complex" Q96JG6 7 93232340-93361123 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA026679 Approved Uncertain "Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 4: Mesenchymal cell lines - Antiviral immune response" "Cluster 66: Spermatocytes - Spermatogenesis" Cytosol "Plasma membrane" "HPA026679: AB_1846135" "unprognostic (2.09e-1)" "unprognostic (1.44e-1)" "unprognostic (1.46e-1)" "unprognostic (3.12e-2)" "unprognostic (7.43e-2)" "unprognostic (4.97e-2)" "prognostic unfavorable (7.21e-5)" "unprognostic (1.05e-1)" "unprognostic (4.79e-2)" "unprognostic (1.37e-1)" "unprognostic (3.69e-1)" "unprognostic (5.17e-2)" "prognostic favorable (1.35e-6)" "unprognostic (2.08e-1)" "unprognostic (3.46e-2)" "unprognostic (1.18e-1)" "unprognostic (1.35e-1)" 7.4 9.0 4.2 3.4 4.6 2.6 8.2 5.7 5.3 7.3 4.6 8.9 1.9 8.2 4.2 9.2 6.8 2.7 7.7 4.4 4.0 7.1 6.1 6.1 4.9 4.1 4.0 7.6 7.8 6.0 7.7 4.8 4.2 6.4 5.2 5.1 8.8 3.2 12.0 8.8 8.2 3.5 4.2 9.5 7.8 6.5 3.8 4.3 7.3 4.9 4.8 7.9 7.8 5.0 6.5 2.2 2.6 5.0 8.2 7.9 6.3 5.5 5.0 9.1 6.1 5.5 9.0 5.5 5.1 4.2 13.6 3.6 10.4 7.0 11.3 5.8 4.6 14.6 3.1 2.4 4.9 3.4 4.5 3.8 8.7 9.9 9.5 5.9 11.5 3.9 10.2 8.2 11.3 4.7 5.3 4.6 6.2 8.7 5.9 3.5 6.3 8.1 5.1 2.9 3.7 7.8 4.8 13.5 4.4 7.5 6.3 2.8 5.8 12.4 4.4 16.3 4.5 3.3 8.0 9.1 6.9 6.1 6.8 3.1 3.2 2.1 2.6 3.5 4.6 2.4 2.7 2.7 4.5 2.4 2.0 2.5 1.1 1.4 2.5 2.8 2.9 2.0 4.2 4.6 5.7 5.3 4.4 4.0 4.1 4.0 4.2 4.2 3.8 5.0 10.9 12.8 11.3 0.0 13.5 0.0 3.4 0.0 6.8 14.1 11.7 6.3 0.0 2.8 5.0 5.5 16.7 7.5 11.0 5.5 3.9 6.2 27.9 7.6 10.8 7.9 2.4 10.8 0.0 5.5 11.7 6.4 11.2 8.2 7.6 12.6 9.7 6.1 10.7 10.1 0.0 7.1 0.0 13.7 0.0 14.2 9.0 10.0 0.0 0.0 9.4 10.3 6.2 0.0 0.0 6.9 9.4 7.2 10.2 2.7 6.1 8.3 5.8 14.3 6.6 11.2 6.3 18.1 12.8 7.9 0.0 9.4 8.5 13.9 5.1 2.8 VPS8 "FLJ32099, KIAA0804" ENSG00000156931 "VPS8 subunit of CORVET complex" Q8N3P4 3 184812143-185052614 "Predicted intracellular proteins" "Protein transport, Transport" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Excitatory neurons: 154.1;Granulosa cells: 124.3;Inhibitory neurons: 132.2;Oligodendrocytes: 149.2" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036871 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 45: Eosinophils - Innate immune response" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 44: HDLM-2 - Immune response" "Cluster 40: Granulosa cells - Unknown function" Cytosol "Plasma membrane" "HPA036871: AB_10672103" "unprognostic (4.36e-2)" "unprognostic (3.97e-3)" "unprognostic (1.53e-1)" "unprognostic (7.95e-2)" "unprognostic (5.11e-2)" "unprognostic (4.43e-2)" "unprognostic (1.27e-3)" "unprognostic (1.74e-1)" "unprognostic (3.21e-2)" "unprognostic (5.98e-3)" "unprognostic (1.98e-1)" "unprognostic (8.82e-2)" "unprognostic (4.74e-2)" "unprognostic (3.15e-1)" "unprognostic (2.56e-1)" "unprognostic (8.10e-3)" "unprognostic (4.97e-2)" 10.9 9.6 18.7 10.0 22.1 23.2 10.6 24.2 24.0 12.7 29.1 11.4 8.3 12.3 16.3 10.1 9.0 11.1 19.6 20.4 23.6 10.6 8.5 10.7 10.5 25.1 21.4 14.3 8.9 15.8 16.3 12.1 26.3 10.9 14.7 16.4 7.9 10.1 28.6 12.9 9.3 12.9 17.1 13.3 13.0 16.9 26.1 11.6 14.9 15.3 10.7 10.4 10.3 36.4 18.0 10.7 15.9 15.9 32.5 28.8 10.6 17.7 18.8 12.3 17.0 13.6 9.0 19.1 29.3 26.9 50.4 20.8 17.3 21.0 23.6 34.8 15.4 20.4 13.0 8.1 20.0 14.3 27.0 20.6 19.4 17.6 17.5 22.6 31.4 17.7 10.9 13.5 22.7 12.8 11.6 8.5 10.5 18.4 10.1 14.1 30.6 15.0 12.2 30.8 16.2 10.6 19.9 20.8 15.6 23.6 33.2 7.5 27.9 18.8 10.5 19.6 15.3 16.5 21.5 25.9 21.6 17.7 15.5 19.0 6.6 22.9 5.0 5.2 4.9 4.4 5.4 5.2 8.1 5.5 8.0 5.4 23.9 5.7 6.6 2.3 4.8 4.3 18.7 22.1 24.2 24.0 20.4 23.6 25.1 21.4 26.3 17.1 26.1 36.4 11.8 12.8 11.5 66.3 17.9 10.5 9.2 8.3 11.4 24.5 8.7 8.3 24.6 11.5 9.7 9.2 18.8 12.8 10.8 17.3 7.9 7.7 22.2 11.0 17.5 12.8 18.0 11.6 154.1 4.6 6.7 14.7 21.9 14.3 2.5 124.3 12.5 7.7 20.2 11.8 132.2 16.6 12.2 19.1 16.7 16.5 10.5 21.2 10.6 89.9 32.0 10.1 32.0 86.5 149.2 6.4 12.7 12.8 14.4 9.4 9.2 8.8 14.4 17.3 6.6 13.0 10.0 94.3 27.8 15.8 16.1 7.7 17.8 11.8 13.2 13.0 VWA7 "C6orf27, G7c, NG37" ENSG00000204396 "Von Willebrand factor A domain containing 7" Q9Y334 6 31765590-31777328 "Predicted secreted proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at transcript level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "pituitary gland: 21.3" "Cell type enhanced" "Detected in some" "Enteroendocrine cells: 4.2;Gastric mucus-secreting cells: 8.2;Proximal enterocytes: 5.0;Proximal tubular cells: 2.4" "Low cancer specificity" "Detected in many" "Group enriched" "Detected in many" 6 "cerebral cortex: 2.9;hypothalamus: 8.2;medulla oblongata: 5.9;pons: 5.5;thalamus: 7.5" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "A549: 1.2;HMC-1: 1.3;Karpas-707: 1.1;U-266/84: 1.6" "Group enriched" "Detected in some" 5 "cerebellum: 7.0;pons and medulla: 3.9" "Low region specificity" "Detected in many" "HPA046954, HPA054262" Approved Approved "Plasma membrane,Cytosol" "Secreted - unknown location" NA NA 9200 "Cluster 10: Basophils - Unknown function" "Cluster 26: Pituitary gland - Hormone signaling" "Cluster 16: U-266 - Nucleosome" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "HPA046954: AB_2679875, HPA054262: AB_2682430" "unprognostic (9.13e-2)" "unprognostic (8.60e-4)" "unprognostic (9.99e-2)" "unprognostic (2.43e-1)" "unprognostic (2.85e-3)" "unprognostic (4.96e-3)" "unprognostic (6.38e-2)" "unprognostic (4.40e-2)" "unprognostic (2.68e-1)" "unprognostic (5.84e-2)" "unprognostic (1.65e-2)" "unprognostic (9.25e-2)" "prognostic favorable (4.35e-8)" "unprognostic (3.75e-2)" "unprognostic (2.37e-1)" "unprognostic (9.48e-2)" "unprognostic (7.66e-2)" 0.4 0.3 0.5 0.1 0.3 0.0 0.7 0.1 2.9 0.8 0.0 1.3 1.0 4.6 0.0 0.4 7.2 0.7 5.2 0.8 8.2 5.7 1.4 1.4 0.1 5.9 1.0 0.5 2.6 1.7 21.3 0.0 5.5 0.8 0.4 0.2 1.4 1.3 6.6 0.8 2.3 0.0 0.0 0.5 3.0 0.7 7.5 0.0 1.8 0.0 0.1 0.6 0.7 1.0 0.8 1.2 0.3 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.0 0.0 0.0 0.3 0.6 0.0 0.0 0.7 0.5 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.7 0.0 0.0 0.1 0.0 0.9 0.0 1.1 0.0 0.1 0.0 0.0 0.1 0.6 0.1 0.3 0.0 0.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.5 0.0 0.0 0.0 1.6 0.0 0.0 0.7 0.0 0.5 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.5 0.3 0.1 2.9 0.8 8.2 5.9 1.0 5.5 0.0 7.5 1.0 0.0 0.0 1.1 0.0 0.6 0.1 0.4 0.5 1.2 0.5 0.1 0.3 0.8 0.0 0.3 1.8 0.0 0.0 0.2 1.4 1.9 0.6 0.0 1.5 0.1 0.1 4.2 0.0 1.5 0.5 0.0 0.1 8.2 0.4 0.0 0.0 0.0 0.1 0.1 0.0 0.1 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.0 0.6 2.1 0.0 0.4 0.3 5.0 2.4 1.6 0.8 0.0 0.0 0.2 0.0 0.0 0.4 0.0 0.3 0.4 0.0 0.5 0.4 WAS "IMD2, THC, WASP, WASPA" ENSG00000015285 "WASP actin nucleation promoting factor" P42768 X 48676596-48691427 "Cancer-related genes, Disease related genes, Human disease related genes, Predicted intracellular proteins" "Cancer-related genes, Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "bone marrow: 58.4;lymphoid tissue: 83.0" "Cell type enhanced" "Detected in many" "B-cells: 83.2;dendritic cells: 91.7;Hofbauer cells: 111.5;Kupffer cells: 110.7;Macrophages: 118.1;monocytes: 88.2;NK-cells: 84.5;Plasma cells: 57.8;T-cells: 99.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in all" "eosinophil: 37.4" "Group enriched" "Detected in all" 4 "granulocytes: 37.4;monocytes: 9.5" "Cell line enhanced" "Detected in some" "Daudi: 76.5;HEL: 67.6;HMC-1: 157.0;MOLT-4: 70.8;NB-4: 75.7;RPMI-8226: 94.0;THP-1: 68.8;U-266/70: 83.1;U-937: 87.4" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA002022, CAB004290" Enhanced Approved "Plasma membrane,Cytosol" NA NA 600000 "Cluster 52: Eosinophils - Transcription" "Cluster 2: Immune cells - Immune response" "Cluster 3: HMC-1 - Innate immune response" "Cluster 19: Monocytes & Neutrophils - Innate immune response" "Plasma membrane" Cytosol "CAB004290: AB_628445, HPA002022: AB_1080581" "unprognostic (1.43e-3)" "unprognostic (2.09e-3)" "unprognostic (2.36e-2)" "prognostic favorable (4.95e-4)" "unprognostic (9.89e-2)" "prognostic favorable (3.78e-4)" "unprognostic (5.12e-3)" "unprognostic (7.60e-2)" "unprognostic (1.54e-2)" "unprognostic (2.86e-1)" "unprognostic (7.40e-2)" "unprognostic (3.60e-1)" "prognostic unfavorable (5.58e-6)" "unprognostic (2.24e-1)" "unprognostic (2.37e-2)" "unprognostic (3.55e-2)" "unprognostic (1.71e-1)" 10.2 5.2 6.3 52.2 5.8 58.4 4.4 5.9 8.1 3.3 6.3 6.4 8.0 2.8 3.0 3.5 5.6 6.9 3.5 6.0 8.0 4.4 7.2 19.1 54.2 11.1 8.2 1.8 2.4 1.4 2.9 9.0 8.6 4.2 5.0 0.4 4.9 2.8 1.4 2.8 23.0 6.1 8.0 83.0 7.0 1.9 8.6 42.0 3.5 3.4 36.2 10.3 3.0 10.8 0.8 0.2 0.4 1.0 0.0 0.0 0.2 0.0 0.0 0.2 0.2 0.6 0.9 76.5 0.3 0.0 0.3 2.0 0.3 0.2 0.0 44.2 0.4 67.6 0.9 0.0 0.8 34.9 157.0 0.3 0.1 0.1 0.0 0.0 0.0 40.3 0.7 45.7 0.0 7.6 70.8 75.7 0.4 1.1 0.4 61.1 0.3 94.0 0.1 0.0 0.5 0.9 1.0 0.7 0.5 0.2 0.4 68.8 0.5 0.1 0.4 1.2 0.1 83.1 43.6 53.7 0.5 87.4 0.2 3.3 7.6 37.4 4.6 8.4 3.4 3.0 3.5 3.9 5.7 3.3 3.1 3.5 29.2 3.6 9.5 3.1 5.4 4.0 6.3 5.8 5.9 8.1 6.0 8.0 11.1 8.2 8.6 8.0 8.6 10.8 1.5 3.2 14.3 0.7 83.2 2.4 0.2 0.2 2.2 0.2 1.1 1.8 1.1 0.0 0.1 0.0 0.0 0.9 91.7 0.3 1.9 0.4 0.6 0.4 0.4 2.6 1.2 14.1 0.3 0.4 1.1 1.5 5.6 0.3 48.1 0.2 3.9 1.6 111.5 0.0 0.3 0.2 0.0 110.7 54.5 1.1 0.0 118.1 3.6 4.7 88.2 0.2 84.5 0.5 0.0 0.1 0.1 0.0 57.8 0.2 0.1 1.8 1.6 0.2 0.0 1.0 1.3 1.3 1.1 0.8 1.4 1.4 99.3 0.4 0.1 0.2 WASF2 "SCAR2, WAVE2" ENSG00000158195 "WASP family member 2" Q9Y6W5 1 27404230-27490167 "Predicted intracellular proteins" "Host-virus interaction" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB022632, HPA045288" Enhanced Approved "Plasma membrane,Cytosol" NA NA 84000 "Cluster 51: Monocytes - Innate immune response" "Cluster 57: Non-specific - Angiogenesis" "Cluster 30: Epithelial cell lines - Translation" "Cluster 22: Epithelial cell types - Mixed function" "Plasma membrane" Cytosol "CAB022632: , HPA045288: AB_2679287" "unprognostic (9.58e-2)" "unprognostic (8.93e-2)" "unprognostic (6.28e-2)" "unprognostic (1.02e-1)" "unprognostic (4.40e-1)" "unprognostic (2.27e-2)" "prognostic unfavorable (5.29e-8)" "unprognostic (3.94e-2)" "unprognostic (4.14e-2)" "prognostic unfavorable (8.48e-4)" "unprognostic (7.60e-3)" "unprognostic (1.10e-1)" "unprognostic (9.15e-3)" "unprognostic (2.24e-1)" "unprognostic (1.56e-1)" "unprognostic (1.47e-1)" "unprognostic (8.26e-2)" 55.2 34.1 37.9 44.1 48.1 59.8 45.8 42.3 36.3 41.3 29.5 49.4 27.5 53.8 21.6 89.8 46.3 31.1 32.9 33.4 39.5 28.4 14.9 45.7 48.1 58.9 49.0 63.5 35.2 31.0 17.0 52.3 53.6 33.1 39.3 9.1 38.3 41.9 18.4 56.7 42.3 51.9 48.2 47.6 40.3 36.8 48.4 54.6 35.5 27.8 52.3 47.8 39.9 50.6 75.4 35.3 80.3 73.4 57.1 74.3 46.5 59.9 55.5 64.7 57.9 30.8 79.2 52.1 56.6 94.4 44.1 58.8 65.5 98.4 77.1 73.3 41.1 113.5 60.5 36.7 76.9 91.9 62.8 68.5 105.1 70.7 130.8 70.0 82.3 56.8 92.3 26.3 89.0 27.1 68.7 42.1 64.9 38.3 53.7 141.8 98.5 53.3 46.3 42.0 39.9 43.8 104.6 46.3 78.3 48.6 38.7 55.1 109.1 53.4 54.8 112.1 47.8 53.6 76.0 67.7 63.0 111.2 61.3 50.0 65.4 54.7 33.3 79.8 27.2 37.8 26.3 23.5 41.7 46.6 26.9 21.2 100.7 24.4 112.7 60.5 28.8 58.6 37.9 48.1 42.3 36.3 33.4 39.5 58.9 49.0 53.6 48.2 48.4 50.6 243.0 67.3 57.5 58.1 112.7 148.1 221.8 245.9 104.2 24.4 143.0 201.9 39.6 75.8 144.1 90.1 14.6 219.2 145.1 147.0 62.6 111.0 51.4 86.6 167.7 194.8 108.5 195.1 19.1 101.7 118.9 157.9 85.1 174.2 58.9 77.7 163.5 48.4 151.2 20.2 12.8 101.9 93.6 250.4 129.2 75.9 165.0 162.7 76.5 93.7 207.6 61.2 142.2 29.1 67.1 164.9 131.8 182.4 74.2 281.7 139.1 50.7 104.4 19.2 138.1 206.1 180.6 120.7 118.1 216.3 194.5 143.5 104.5 79.3 120.3 372.5 WDR1 ENSG00000071127 "WD repeat domain 1" O75083 4 10074339-10116949 "Plasma proteins, Predicted intracellular proteins" Actin-binding "Disease variant" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in all" "Late spermatids: 1232.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB020804, HPA036434, HPA070293" Approved Supported "Plasma membrane,Cell Junctions" NA NA 63000000 "Cluster 8: Neutrophils - Inflammatory response" "Cluster 12: Smooth muscle tissue - Mixed function" "Cluster 10: BJ & FHDF - ECM organization" "Cluster 34: Spermatids - Unknown function" "Plasma membrane, Cell Junctions" "CAB020804: , HPA036434: AB_2675121, HPA070293: AB_2732152" "unprognostic (1.35e-1)" "unprognostic (6.64e-2)" "unprognostic (5.31e-2)" "unprognostic (1.32e-3)" "unprognostic (2.65e-1)" "unprognostic (1.22e-1)" "unprognostic (2.63e-3)" "unprognostic (6.83e-3)" "unprognostic (1.69e-1)" "unprognostic (9.00e-3)" "unprognostic (2.52e-2)" "unprognostic (2.61e-1)" "prognostic favorable (1.73e-5)" "unprognostic (1.11e-1)" "unprognostic (3.56e-1)" "unprognostic (3.46e-2)" "unprognostic (4.83e-3)" 133.7 77.7 60.2 194.5 58.1 150.9 107.8 56.8 65.4 147.1 104.2 200.8 149.1 261.1 91.0 165.1 179.5 117.4 134.2 69.7 69.7 119.4 84.2 142.8 174.6 68.4 69.7 120.5 63.7 89.6 58.4 105.4 68.6 124.5 141.5 93.0 124.9 173.7 94.8 110.4 148.3 214.6 63.1 110.0 131.7 131.9 62.6 188.0 109.8 89.5 149.6 203.0 139.3 68.8 249.5 246.9 213.2 179.4 160.1 265.9 336.9 612.9 561.7 542.9 423.1 296.4 303.3 173.6 193.3 744.4 579.3 158.8 237.3 451.0 582.4 270.7 82.8 494.1 244.6 213.8 377.9 159.4 538.6 256.7 228.4 552.9 276.3 418.7 599.3 301.6 151.6 273.3 540.7 142.8 700.1 229.0 253.4 200.7 250.4 327.8 197.7 146.7 344.9 394.7 72.4 80.5 265.6 141.3 257.3 282.9 120.1 173.9 909.9 415.7 174.6 345.7 548.0 173.4 296.4 225.5 439.7 240.4 522.9 177.4 115.7 213.6 172.3 195.9 134.4 81.6 143.8 173.0 141.4 61.1 145.6 156.9 201.5 129.0 246.9 154.5 214.9 298.4 60.2 58.1 56.8 65.4 69.7 69.7 68.4 69.7 68.6 63.1 62.6 68.8 66.5 35.3 52.9 10.1 77.0 145.3 204.6 103.5 46.7 22.0 65.9 68.7 62.9 52.9 87.4 104.8 41.7 172.5 126.7 347.1 86.1 282.5 500.8 72.2 63.8 103.6 109.2 56.8 4.7 211.3 302.4 68.7 118.3 111.7 82.4 78.7 84.3 71.8 249.2 33.7 8.4 152.6 138.4 159.4 135.8 1232.1 46.9 174.9 80.0 15.0 303.7 82.6 147.2 11.6 9.6 322.8 244.4 92.2 78.3 150.7 169.0 113.1 73.5 28.0 98.6 46.1 168.1 81.6 64.3 74.9 137.0 231.6 132.2 77.2 172.8 193.6 WDR53 "MGC12928, MGC64882" ENSG00000185798 "WD repeat domain 53" Q7Z5U6 3 196554177-196568674 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Tissue enriched" "Detected in all" 5 "testis: 74.2" "Group enriched" "Detected in many" 9 "Early spermatids: 313.9;Late spermatids: 118.8;Spermatocytes: 135.6" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA016420 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 33: Neutrophils - Chromatin organization" "Cluster 78: Testis - Spermatogenesis" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane, Cytosol" "HPA016420: AB_1858812" "unprognostic (3.29e-2)" "unprognostic (4.24e-3)" "unprognostic (9.89e-2)" "unprognostic (2.29e-3)" "unprognostic (2.26e-1)" "unprognostic (4.71e-2)" "prognostic unfavorable (1.57e-6)" "unprognostic (4.49e-2)" "prognostic unfavorable (3.09e-4)" "unprognostic (2.57e-1)" "unprognostic (2.10e-3)" "unprognostic (4.48e-3)" "unprognostic (8.01e-3)" "unprognostic (1.68e-1)" "unprognostic (1.12e-1)" "unprognostic (5.38e-2)" "unprognostic (1.97e-1)" 7.8 7.4 9.4 6.9 10.3 14.7 9.0 10.3 12.1 7.7 9.7 8.1 4.3 8.1 11.0 9.0 7.1 6.3 8.1 9.5 10.0 8.8 10.0 6.9 10.6 9.6 9.7 7.0 5.9 10.0 6.7 6.3 11.2 7.2 7.1 8.9 7.0 6.1 13.0 11.9 7.9 7.4 9.4 10.8 7.2 74.2 9.8 12.1 7.1 12.6 11.9 7.2 7.6 11.3 39.4 8.5 14.6 13.6 15.0 13.2 23.8 20.1 16.2 23.0 21.7 22.8 20.2 18.9 66.4 13.0 21.2 22.3 18.9 18.4 28.8 30.0 16.3 19.4 21.2 14.6 18.5 26.9 14.3 10.7 25.9 20.6 22.2 11.4 18.7 23.6 18.8 34.5 17.7 36.4 22.5 27.5 19.5 25.7 24.4 26.5 25.3 40.5 12.8 13.4 15.0 15.2 15.0 20.8 32.2 19.8 53.0 24.2 17.2 18.9 18.0 21.5 40.6 29.5 63.8 56.6 12.7 34.2 19.4 13.1 5.5 15.7 8.8 4.7 14.1 7.8 12.2 8.5 4.7 7.5 10.2 6.1 4.7 7.4 7.8 6.2 16.5 5.0 9.4 10.3 10.3 12.1 9.5 10.0 9.6 9.7 11.2 9.4 9.8 11.3 3.9 0.0 2.8 6.8 3.8 4.2 3.2 8.1 2.8 3.7 3.4 3.4 5.6 2.8 5.8 3.7 0.0 5.7 3.5 1.7 5.9 5.0 313.9 3.3 3.5 4.7 0.0 7.4 5.5 4.2 6.1 3.9 0.5 2.7 9.5 3.2 3.9 2.5 4.3 3.3 4.8 1.6 10.2 3.8 3.0 118.8 5.0 3.9 5.4 10.3 7.3 4.0 4.1 6.0 7.1 3.7 1.9 3.4 3.7 2.9 1.5 5.0 3.1 2.8 19.7 4.0 5.5 135.6 13.9 3.5 4.7 4.7 6.3 4.1 2.7 2.6 WDR6 ENSG00000178252 "WD repeat domain 6" Q9NNW5 3 49007062-49015953 "Predicted intracellular proteins" "Cell cycle" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA042622 Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 39: Non-specific - mRNA processing" "Cluster 35: Non-specific - Unknown function" "Cluster 20: HeLa - Mitochondria" "Cluster 52: Non-specific - Transcription" Cytosol "Plasma membrane" "HPA042622: AB_10966784" "unprognostic (2.41e-2)" "unprognostic (2.03e-1)" "unprognostic (2.14e-1)" "unprognostic (1.26e-2)" "unprognostic (4.80e-2)" "unprognostic (1.05e-1)" "prognostic unfavorable (2.97e-6)" "unprognostic (1.79e-2)" "unprognostic (1.90e-1)" "unprognostic (1.20e-1)" "unprognostic (1.01e-3)" "unprognostic (1.94e-2)" "prognostic favorable (4.52e-5)" "unprognostic (1.13e-1)" "unprognostic (1.51e-1)" "unprognostic (1.87e-1)" "unprognostic (1.61e-2)" 67.5 148.8 108.7 51.9 106.3 41.8 69.8 104.9 124.5 153.1 120.1 130.1 66.5 122.8 83.1 65.1 129.8 59.7 82.7 105.8 116.3 113.7 97.7 77.8 61.2 105.1 112.8 205.9 136.7 91.0 207.4 46.1 108.1 159.3 50.9 49.4 99.2 74.1 71.4 63.7 105.4 68.1 102.0 112.9 93.3 61.2 120.9 54.7 178.2 37.8 53.5 118.8 90.5 107.2 61.4 82.4 133.7 113.7 87.8 71.1 90.1 89.4 73.1 98.7 79.4 73.9 86.2 98.3 55.5 143.2 75.8 68.1 107.8 125.0 70.0 78.3 71.8 93.1 223.0 98.8 88.8 97.3 40.3 128.5 87.3 91.1 68.4 136.2 73.0 101.8 54.0 102.4 90.6 121.7 113.5 109.8 119.1 55.7 75.9 65.5 57.3 61.8 117.6 179.3 64.9 121.0 66.8 54.1 40.6 96.9 94.8 76.7 98.4 72.7 116.1 71.3 121.1 177.3 82.7 84.3 98.7 122.2 53.4 6.4 11.5 12.8 19.0 15.5 21.1 13.0 13.9 14.4 13.5 12.8 15.8 12.2 3.9 14.6 8.0 17.0 12.6 16.8 108.7 106.3 104.9 124.5 105.8 116.3 105.1 112.8 108.1 102.0 120.9 107.2 16.0 22.4 48.5 67.9 28.0 17.8 24.3 32.0 27.9 26.0 48.1 43.1 3.1 42.9 38.5 47.8 47.9 46.5 21.4 18.4 9.8 30.7 4.3 34.6 32.3 20.8 72.3 16.6 9.3 26.0 21.0 24.1 36.7 39.2 29.1 66.7 26.0 44.7 26.8 37.0 17.5 32.3 28.5 19.2 20.2 7.0 38.2 18.7 12.4 22.5 24.7 39.0 12.3 27.2 23.3 28.0 23.5 28.2 29.9 26.2 30.8 31.3 26.2 46.4 26.3 20.0 21.0 43.0 34.9 15.5 11.4 56.5 25.9 44.7 36.4 19.9 WIPF1 "WASPIP, WIP" ENSG00000115935 "WAS/WASL interacting protein family member 1" O43516 2 174559572-174682916 "Disease related genes, Human disease related genes, Predicted intracellular proteins" Actin-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in all" "lymphoid tissue: 126.9" "Cell type enhanced" "Detected in many" "dendritic cells: 172.7;monocytes: 187.2;NK-cells: 245.1;Oligodendrocytes: 217.2;Plasma cells: 162.8;T-cells: 208.1" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enhanced" "Detected in many" "Daudi: 209.1;Karpas-707: 296.8;U-266/70: 233.0" "Low region specificity" "Detected in all" "HPA003739, CAB009737, HPA070706" Enhanced Approved "Plasma membrane,Cytosol" No No 520000 "Cluster 5: Granulocytes - Unknown function" "Cluster 16: Immune cells - Immune response" "Cluster 2: Karpas-707 - Immune response" "Cluster 63: NK-cells & T-cells - Immune response" Cytosol "Plasma membrane" "CAB009737: AB_2288577, HPA003739: AB_1858783, HPA070706: AB_2686300" "unprognostic (4.76e-2)" "unprognostic (4.80e-2)" "unprognostic (1.49e-1)" "unprognostic (9.88e-2)" "unprognostic (1.87e-1)" "unprognostic (2.27e-3)" "unprognostic (2.05e-1)" "unprognostic (1.21e-1)" "unprognostic (7.22e-2)" "unprognostic (1.26e-1)" "unprognostic (3.25e-2)" "unprognostic (1.46e-1)" "prognostic unfavorable (1.14e-4)" "unprognostic (3.65e-2)" "unprognostic (5.43e-2)" "unprognostic (1.58e-1)" "unprognostic (2.50e-2)" 31.0 14.7 14.2 93.0 37.2 56.8 21.0 36.1 20.5 30.6 11.1 26.0 18.2 22.4 11.5 14.2 14.4 34.8 16.0 14.9 28.8 13.0 16.4 31.8 126.9 46.2 38.6 12.3 7.3 12.9 4.8 33.5 42.3 14.9 20.8 3.4 17.7 23.0 5.9 9.9 32.5 29.1 27.9 89.7 21.8 4.7 35.1 66.4 15.4 11.5 110.5 31.5 17.0 53.8 0.7 7.0 16.3 0.2 40.4 70.9 16.9 31.1 26.4 12.1 18.7 1.9 1.4 209.1 9.2 47.0 15.6 0.5 2.8 0.0 15.1 144.8 4.1 106.5 26.9 0.0 15.1 94.9 167.2 29.6 5.1 27.7 2.6 16.0 25.0 18.7 3.3 296.8 34.4 0.1 106.6 87.1 19.1 0.0 1.4 90.0 6.6 37.9 11.3 0.7 2.6 33.8 0.3 8.8 18.7 30.4 0.4 46.8 21.2 41.0 11.5 30.1 29.9 233.0 165.2 113.7 60.4 64.7 111.7 41.5 35.4 87.2 71.6 37.3 59.4 35.1 47.6 71.1 26.1 28.6 38.0 51.4 166.1 57.4 43.7 11.2 57.7 54.7 14.2 37.2 36.1 20.5 14.9 28.8 46.2 38.6 42.3 27.9 35.1 53.8 32.1 19.2 21.7 27.7 134.5 12.5 6.3 0.9 2.8 2.1 3.3 4.3 10.5 1.5 4.6 3.7 25.0 2.0 172.7 0.3 5.9 1.7 40.2 3.3 21.9 30.8 4.9 30.1 5.3 11.6 82.5 40.5 9.7 2.1 67.2 2.1 36.8 3.7 86.2 0.0 7.2 1.6 0.0 142.2 128.0 96.9 25.1 139.8 26.6 98.4 187.2 1.2 245.1 120.6 217.2 16.8 0.8 18.0 162.8 5.0 0.2 35.9 0.1 3.4 13.1 15.7 21.4 4.4 4.1 1.2 11.1 4.1 208.1 8.8 2.1 3.1 XAGE2 "CT12.2, GAGED3, XAGE-2, XAGE2B" ENSG00000155622 "X antigen family member 2" Q96GT9 X 52369021-52375680 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 35 "placenta: 199.5" "Group enriched" "Detected in some" 13 "Cytotrophoblasts: 1027.3;Extravillous trophoblasts: 1890.1;Syncytiotrophoblasts: 1367.6" "Cancer enhanced" "Detected in many" "ovarian cancer: 4.5" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 96.3;SK-BR-3: 22.7;SuSa: 27.9;T-47d: 20.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 28: Placenta - Pregnancy" "Cluster 28: BEWO - Transcription regulation" "Cluster 38: Extravillous trophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (1.21e-1)" "unprognostic (9.67e-2)" "unprognostic (1.49e-1)" "unprognostic (4.47e-2)" 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.2 0.0 5.6 0.0 0.0 0.0 0.1 0.4 0.0 0.0 199.5 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.1 0.1 0.0 0.0 0.0 0.5 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.0 0.0 96.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.0 0.0 4.3 0.8 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.1 0.2 0.0 22.7 1.2 27.9 20.1 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 8.5 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 38.5 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 1027.3 0.0 0.0 0.0 0.1 0.0 0.1 0.0 2.0 0.0 0.0 0.0 0.0 1890.1 6.7 0.0 0.0 0.0 0.0 0.0 0.0 107.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.2 0.0 0.0 0.0 0.0 0.2 2.1 0.0 0.0 1367.6 0.0 0.0 0.0 0.0 XAGE3 "CT12.3a, CT12.3b, GAGED4, PLAC6, pp9012, XAGE-3" ENSG00000171402 "X antigen family member 3" Q8WTP9 X 52862525-52868083 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in some" 121 "placenta: 382.1" "Group enriched" "Detected in some" 10 "Cytotrophoblasts: 2223.5;Extravillous trophoblasts: 1309.1;Syncytiotrophoblasts: 2678.1" "Low cancer specificity" "Detected in some" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BEWO: 1.1;U-266/70: 2.2;U-266/84: 2.1" "HPA052507, HPA060900" Supported Approved "Vesicles,Plasma membrane" NA NA "Cluster 43: B-cells - Humoral immune response" "Cluster 28: Placenta - Pregnancy" "Cluster 29: U-266 - Adaptive immune response" "Cluster 47: Cytotrophoblasts - Unknown function" Vesicles "Plasma membrane" "HPA052507: AB_2681855, HPA060900: AB_2684383" "unprognostic (6.04e-2)" "unprognostic (2.30e-1)" "unprognostic (2.92e-1)" 3.1 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.1 0.0 0.0 0.0 0.1 0.0 0.6 0.0 0.0 0.0 0.1 0.0 0.0 0.1 2.0 0.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 382.1 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 1.4 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.3 0.4 0.2 0.2 0.0 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.0 2.2 2.1 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 1.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.0 0.0 0.0 0.0 2223.5 0.0 0.1 0.0 0.2 0.3 0.1 0.0 4.5 0.0 0.0 0.0 0.4 1309.1 11.1 0.0 0.3 0.0 0.0 0.0 4.6 191.1 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 0.7 0.0 0.0 0.0 0.0 0.4 15.1 7.0 0.0 0.0 2678.1 0.0 0.0 0.1 0.0 XIRP2 CMYA3 ENSG00000163092 "Xin actin binding repeat containing 2" A4UGR9 2 166888480-167259753 "Cancer-related genes, Plasma proteins, Predicted intracellular proteins" Actin-binding "Cancer-related genes" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in some" "heart muscle: 202.3;skeletal muscle: 1034.1;tongue: 543.2" "Cell type enriched" "Detected in some" 19 "Cardiomyocytes: 1907.2" "Cancer enriched" "Detected in some" 5 "head and neck cancer: 3.4" "Not detected" "Not detected" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "AN3-CA: 1.6;HUVEC TERT2: 4.2;U-2197: 2.9" "Not detected" "Not detected" "Not detected" "Not detected" "HPA034813, HPA074599" Enhanced Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 13: Striated muscle - Muscle contraction" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 54: Cardiomyocytes - Muscle contraction" "Plasma membrane" Nucleoplasm "HPA034813: AB_10602588, HPA074599: " "unprognostic (5.27e-4)" "unprognostic (5.96e-3)" "unprognostic (7.42e-2)" "unprognostic (2.42e-1)" "unprognostic (1.74e-1)" "unprognostic (2.56e-1)" 0.2 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 2.5 0.0 0.0 202.3 0.0 0.0 0.0 0.1 0.3 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.0 0.0 5.9 0.0 0.0 8.0 0.0 1034.1 1.2 0.1 0.0 0.0 0.5 0.1 3.0 0.0 0.1 0.3 543.2 0.1 0.0 0.1 0.0 0.0 0.0 0.0 1.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.7 0.0 0.1 0.1 0.0 0.0 0.4 0.0 0.1 0.3 0.0 4.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.2 0.0 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 2.9 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.6 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1907.2 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 38.5 0.0 0.0 10.1 0.0 0.0 1.9 0.0 0.0 15.1 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 1.8 0.0 0.0 0.0 0.0 23.3 0.0 1.6 0.0 0.0 0.0 0.0 0.0 2.5 1.2 0.0 1.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 98.4 5.8 1.0 0.4 0.0 0.0 0.0 0.2 0.0 0.0 0.0 XPC "RAD4, XPCC" ENSG00000154767 "XPC complex subunit, DNA damage recognition and repair factor" Q01831 3 14145147-14178621 "Cancer-related genes, Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "DNA damage, DNA repair, Transcription, Transcription regulation" DNA-binding "Cancer-related genes, Disease variant, Xeroderma pigmentosum" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB009932, HPA035707, HPA069673" Supported Enhanced "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 72: Non-specific - Transcription" "Cluster 28: BEWO - Transcription regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "CAB009932: AB_2241587, HPA035707: AB_2674743, HPA069673: AB_2686167" "unprognostic (7.46e-2)" "unprognostic (2.52e-2)" "unprognostic (4.50e-2)" "unprognostic (3.01e-1)" "unprognostic (6.63e-2)" "unprognostic (2.54e-2)" "unprognostic (1.97e-1)" "unprognostic (5.65e-2)" "unprognostic (1.50e-1)" "unprognostic (7.13e-3)" "unprognostic (4.39e-2)" "unprognostic (2.07e-1)" "prognostic favorable (4.14e-7)" "unprognostic (1.59e-1)" "unprognostic (7.88e-2)" "unprognostic (7.62e-2)" "prognostic favorable (2.46e-4)" 22.9 17.2 14.3 16.4 17.3 10.2 22.9 15.6 14.6 27.2 15.2 20.1 19.0 24.9 17.6 16.1 25.3 16.6 13.1 12.9 17.3 24.8 24.2 20.7 24.5 16.8 17.4 34.6 21.6 24.0 25.8 15.6 17.4 22.9 15.6 15.2 18.5 23.6 21.3 31.9 24.0 17.5 15.2 24.2 17.4 12.4 16.0 21.2 26.7 9.8 21.7 22.9 20.3 18.3 14.3 33.8 36.7 22.6 51.0 35.8 124.8 33.6 88.7 29.9 22.3 11.8 14.7 46.6 14.5 37.5 14.7 15.6 23.6 49.3 23.6 21.5 24.7 24.9 35.7 21.7 45.0 16.8 42.2 50.1 56.4 39.7 77.4 34.2 34.5 19.0 31.2 22.5 32.5 27.2 17.9 16.3 23.5 20.4 21.2 19.3 17.9 33.7 36.2 36.9 8.8 29.9 36.1 27.2 23.5 54.6 29.9 13.8 57.1 11.2 32.1 18.4 15.4 54.5 46.4 25.4 26.5 19.4 41.6 41.4 20.2 26.8 23.2 16.6 22.7 27.1 26.7 23.5 17.9 25.0 28.3 20.8 73.1 24.3 23.3 17.4 24.7 16.9 14.3 17.3 15.6 14.6 12.9 17.3 16.8 17.4 17.4 15.2 16.0 18.3 26.0 60.9 63.2 16.6 39.9 13.8 20.4 25.5 59.2 35.6 19.0 25.9 11.8 31.5 47.7 16.5 39.6 42.5 38.9 13.4 35.2 19.3 2.3 32.2 44.8 29.9 16.3 20.8 18.0 19.2 20.3 29.2 15.3 25.5 47.4 25.0 22.9 40.5 18.2 26.9 22.0 13.9 20.3 23.9 14.9 2.7 30.7 19.6 8.8 15.0 40.1 24.9 54.6 17.1 27.5 19.5 15.0 28.2 29.1 18.9 32.7 66.1 55.0 51.0 26.3 43.3 27.7 28.7 54.9 21.4 11.1 32.0 42.3 26.3 18.1 10.5 XPNPEP2 ENSG00000122121 "X-prolyl aminopeptidase 2" O43895 X 129738949-129769536 "Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins" "Aminopeptidase, Hydrolase, Metalloprotease, Protease" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 7 "intestine: 166.6;kidney: 156.0" "Cell type enriched" "Detected in some" 6 "Proximal enterocytes: 475.9" "Cancer enhanced" "Detected in many" "liver cancer: 18.3" "Not detected" "Not detected" "Group enriched" "Detected in many" 4 "gdT-cell: 4.3;intermediate monocyte: 1.4;MAIT T-cell: 1.2;memory CD4 T-cell: 1.3;memory CD8 T-cell: 2.8;naive CD8 T-cell: 2.0;non-classical monocyte: 2.8;T-reg: 1.4" "Group enriched" "Detected in many" 7 "monocytes: 2.8;T-cells: 4.3" "Cell line enhanced" "Detected in some" "ASC diff: 8.2;ASC TERT1: 40.1;HSkMC: 21.1" "Not detected" "Not detected" "Low region specificity" "Detected in many" "HPA000339, CAB025136, CAB025269, HPA064568" Enhanced Approved "Plasma membrane,Cytosol" "Intracellular and membrane" NA NA 13000000 "Cluster 36: GdT-cells - Adaptive immune response" "Cluster 87: Intestine & Kidney - Transmembrane transport" "Cluster 34: Mesenchymal cell lines - ECM organization" "Cluster 45: Enterocytes - Digestion" "Plasma membrane, Cytosol" "CAB025136: , CAB025269: , HPA000339: AB_1858894, HPA064568: " "unprognostic (7.95e-2)" "unprognostic (5.73e-2)" "unprognostic (2.56e-1)" "unprognostic (6.21e-3)" "unprognostic (3.54e-2)" "unprognostic (1.54e-1)" "unprognostic (4.04e-1)" "unprognostic (3.26e-1)" "unprognostic (3.01e-1)" "unprognostic (2.41e-2)" "unprognostic (3.07e-1)" "unprognostic (9.28e-3)" "unprognostic (2.77e-2)" "unprognostic (6.53e-2)" "unprognostic (3.18e-2)" "unprognostic (1.39e-2)" "unprognostic (3.26e-3)" 7.5 0.9 0.1 3.7 0.1 0.2 3.0 0.1 0.1 3.7 0.1 5.5 99.0 2.4 0.1 2.2 6.3 4.3 5.3 0.1 0.1 156.0 23.1 2.1 0.5 0.2 0.1 1.8 0.3 0.3 0.1 1.2 0.1 1.8 6.3 0.0 1.5 0.4 0.5 4.4 166.6 6.0 0.1 0.3 3.4 0.1 0.1 1.0 1.4 2.4 0.4 7.8 4.0 0.1 0.0 0.0 0.5 0.0 8.2 40.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 1.2 0.0 0.0 21.1 0.0 0.0 0.0 0.0 0.0 1.0 0.0 0.0 0.0 0.0 0.3 0.4 0.0 0.0 0.0 0.7 0.0 0.7 0.0 0.0 0.1 1.3 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 1.5 0.0 0.1 0.0 0.3 0.0 0.0 0.0 0.0 0.1 0.0 4.3 1.4 1.2 0.0 1.3 2.8 0.2 0.2 0.4 2.0 0.1 0.0 2.8 0.4 1.4 0.9 0.1 0.1 0.1 0.1 0.1 0.1 0.2 0.1 0.1 0.1 0.1 0.1 1.2 0.0 0.0 0.0 0.5 1.9 0.0 0.0 0.0 0.0 0.0 0.0 0.8 0.0 0.0 1.8 0.0 0.2 0.5 11.4 5.9 0.0 0.0 0.0 0.1 0.3 1.2 0.0 0.2 0.0 0.0 10.0 1.1 0.0 0.0 0.0 0.4 18.5 0.8 0.0 0.3 12.8 0.0 1.0 3.6 0.0 0.0 1.0 1.8 1.0 0.0 0.0 3.1 0.0 0.1 0.0 21.0 0.0 0.1 0.0 475.9 75.1 0.0 0.0 0.0 0.3 0.3 0.0 0.0 0.0 1.0 1.2 0.9 0.0 8.4 0.0 XRN1 SEP1 ENSG00000114127 "5'-3' exoribonuclease 1" Q8IZH2 3 142306607-142448062 "Predicted intracellular proteins" "DNA-binding, Exonuclease, Hydrolase, Nuclease, RNA-binding" "Tumor suppressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Cell line enriched" "Detected in all" 4 "RH-30: 119.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA035005, HPA035006" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 34: Non-specific - Transcription" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 59: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA035005: AB_10670695, HPA035006: AB_10672750" "unprognostic (3.52e-1)" "unprognostic (2.35e-2)" "unprognostic (2.49e-1)" "unprognostic (1.35e-2)" "unprognostic (2.40e-2)" "unprognostic (1.68e-2)" "unprognostic (1.24e-1)" "unprognostic (2.67e-1)" "unprognostic (1.06e-1)" "unprognostic (2.16e-2)" "prognostic unfavorable (9.43e-4)" "unprognostic (7.68e-2)" "unprognostic (6.16e-2)" "unprognostic (1.23e-1)" "unprognostic (2.41e-1)" "unprognostic (2.43e-2)" "unprognostic (6.32e-2)" 9.0 6.8 2.9 12.2 4.5 21.2 10.7 11.4 5.5 8.4 6.4 8.2 11.0 9.8 7.8 7.0 6.2 8.0 5.5 3.2 4.0 6.8 16.2 8.6 13.1 3.8 3.2 10.1 8.1 8.8 6.0 10.5 4.2 8.8 9.4 14.6 7.4 6.1 11.7 9.4 12.4 6.6 4.5 12.8 9.0 9.3 3.9 14.4 8.7 9.7 11.3 7.7 8.2 6.8 22.1 3.9 9.6 8.6 11.1 17.0 5.9 9.9 12.9 12.3 15.2 3.6 6.1 8.9 10.3 13.3 10.0 8.6 8.6 5.2 19.2 21.4 6.5 12.7 7.3 3.5 9.6 12.8 12.7 14.0 6.1 8.8 11.7 12.1 11.4 9.7 8.0 20.4 11.7 4.5 11.2 7.6 3.0 3.4 4.4 9.0 119.2 11.4 6.5 10.8 5.7 7.3 17.3 10.4 8.2 5.9 11.9 10.8 16.0 9.0 4.7 10.3 8.7 29.1 14.2 13.7 8.4 7.2 7.9 31.0 5.8 17.2 10.0 5.4 7.1 9.8 7.7 9.1 2.9 7.2 10.1 7.0 21.2 5.9 5.0 8.0 6.2 3.1 2.9 4.5 11.4 5.5 3.2 4.0 3.8 3.2 4.2 4.5 3.9 6.8 66.1 54.5 33.3 74.7 55.9 25.6 33.7 22.7 33.6 33.7 27.2 21.0 26.5 18.6 30.2 46.0 50.1 22.9 80.8 46.5 11.7 16.5 49.9 31.9 50.7 40.6 28.2 43.6 101.6 12.5 7.8 41.8 48.4 29.0 21.5 33.7 33.9 48.0 16.3 26.9 114.2 22.5 14.2 28.9 23.0 19.1 24.8 38.8 14.2 81.5 41.4 21.0 50.4 126.7 120.4 18.6 41.9 29.0 111.7 44.0 43.4 13.2 34.2 53.9 6.6 56.0 39.9 61.8 20.5 27.6 28.3 53.5 69.8 37.1 15.0 43.8 XYLT1 "PXYLT1, XT-I" ENSG00000103489 "Xylosyltransferase 1" Q86Y38 16 17101769-17470960 "Disease related genes, Enzymes, Human disease related genes, Metabolic proteins, Potential drug targets, Predicted secreted proteins" "Glycosyltransferase, Transferase" "Disease variant, Dwarfism" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enriched" "Detected in many" 6 "Oligodendrocyte precursor cells: 1194.8" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in some" "non-classical monocyte: 2.0" "Lineage enriched" "Detected in single" 4 "monocytes: 2.0" "Cell line enhanced" "Detected in many" "ASC diff: 55.1;ASC TERT1: 34.0;U-2197: 57.2" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA007478, HPA007966" Approved Approved "Endoplasmic reticulum,Plasma membrane" "Secreted to blood" NA NA 150000 "Cluster 14: Monocytes - Unknown function" "Cluster 10: Brain - Neuronal signaling" "Cluster 18: U-2197 - ECM organization" "Cluster 68: Oligodendrocytes - Mixed function" "Plasma membrane" "Endoplasmic reticulum" "HPA007478: AB_1080616, HPA007966: AB_1080618" "unprognostic (1.82e-1)" "unprognostic (7.17e-2)" "unprognostic (1.63e-1)" "unprognostic (1.38e-2)" "unprognostic (2.83e-1)" "unprognostic (9.12e-2)" "unprognostic (8.13e-2)" "unprognostic (9.40e-2)" "unprognostic (2.41e-3)" "unprognostic (2.82e-2)" "unprognostic (2.11e-1)" "unprognostic (1.01e-1)" "unprognostic (8.66e-3)" "unprognostic (2.49e-1)" "unprognostic (1.76e-1)" "unprognostic (2.95e-1)" "unprognostic (6.05e-2)" 6.4 6.2 6.2 4.9 8.0 7.2 4.5 2.3 6.3 7.8 8.5 8.8 4.3 7.9 1.0 5.1 3.7 2.3 4.2 8.8 3.6 1.0 0.3 3.5 5.1 3.7 4.3 5.3 2.8 0.9 0.6 6.0 4.2 2.7 5.2 8.3 2.5 4.5 1.1 5.0 5.3 5.7 1.6 5.4 3.4 2.3 3.6 4.1 2.2 1.2 4.3 4.3 4.6 4.6 0.0 0.3 8.0 0.1 55.1 34.0 9.6 25.6 12.9 2.7 1.0 0.3 0.6 6.1 0.0 31.3 0.9 0.6 0.0 5.1 4.5 12.1 0.6 8.0 0.0 0.0 0.6 11.5 10.2 12.6 0.7 15.0 2.4 4.6 0.0 0.3 0.0 23.8 2.8 0.8 0.1 12.4 8.5 4.4 0.0 3.5 0.0 1.2 0.0 11.5 2.0 15.2 1.9 7.9 1.4 5.9 1.9 7.2 0.0 24.6 2.9 57.2 0.0 26.4 1.4 11.6 28.9 12.8 22.4 0.3 0.2 0.4 0.2 1.2 0.3 0.1 0.1 0.1 0.4 0.3 0.2 0.1 0.1 0.4 2.0 0.1 0.3 0.2 6.2 8.0 2.3 6.3 8.8 3.6 3.7 4.3 4.2 1.6 3.6 4.6 1.0 3.2 2.5 45.4 9.2 7.9 1.6 0.0 1.2 12.9 3.8 3.7 3.4 0.0 0.7 0.0 98.0 12.7 12.4 9.1 0.0 1.5 0.5 0.5 24.7 2.9 12.6 7.4 172.8 1.6 20.1 12.2 2.6 0.8 2.5 6.4 1.4 0.2 3.5 0.0 72.8 4.3 4.1 9.7 27.6 0.8 12.8 8.5 3.6 29.0 6.1 1.9 11.3 1194.8 63.0 4.0 7.4 50.0 6.2 5.3 6.1 0.2 0.0 4.4 6.6 7.9 5.9 0.3 1.6 4.1 18.5 13.1 7.7 8.1 6.9 6.4 YES1 "c-yes, HsT441, Yes" ENSG00000176105 "YES proto-oncogene 1, Src family tyrosine kinase" P07947 18 721588-812546 "Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins, Predicted intracellular proteins" "Kinase, Transferase, Tyrosine-protein kinase" "FDA approved drug targets, Proto-oncogene" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in many" 9 "basophil: 20.2" "Lineage enriched" "Detected in many" 9 "granulocytes: 20.2" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "CAB004370, HPA026480" Approved Supported "Plasma membrane,Cytosol" NA NA "Cluster 38: Basophils - Unknown function" "Cluster 86: Liver & Placenta - Transport via ER" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" "Plasma membrane, Cytosol" "CAB004370: AB_627370, HPA026480: AB_1858921" "unprognostic (3.28e-1)" "unprognostic (1.62e-2)" "unprognostic (5.87e-2)" "unprognostic (2.47e-2)" "unprognostic (6.24e-2)" "unprognostic (4.24e-2)" "unprognostic (6.01e-2)" "unprognostic (1.03e-2)" "unprognostic (1.95e-2)" "unprognostic (1.85e-3)" "prognostic unfavorable (2.46e-4)" "unprognostic (2.14e-1)" "unprognostic (8.12e-2)" "unprognostic (4.65e-2)" "unprognostic (1.81e-1)" "unprognostic (4.79e-2)" "unprognostic (4.11e-1)" 25.2 13.5 11.9 10.5 12.7 4.1 21.8 12.7 14.3 17.4 11.5 21.8 24.8 16.0 17.9 22.7 13.9 18.9 13.1 11.7 13.7 27.9 50.6 17.2 6.2 13.9 13.2 12.4 26.5 20.0 6.1 41.7 13.5 15.0 22.7 8.3 21.0 11.9 8.3 16.7 23.7 15.9 14.2 27.4 21.3 19.0 14.3 10.5 22.0 14.6 8.8 20.3 11.5 14.1 42.7 20.8 64.3 50.6 37.8 46.5 75.6 27.9 56.2 32.0 43.7 49.9 30.7 0.1 28.8 47.3 41.0 24.3 60.8 49.1 62.3 0.2 20.7 12.6 19.4 35.1 30.6 9.9 21.7 35.7 51.7 48.5 53.6 39.8 109.8 7.0 56.1 18.4 46.1 29.3 6.0 13.0 40.9 26.0 26.4 7.4 50.6 3.6 46.8 49.6 13.1 15.3 57.5 42.9 37.1 42.3 29.7 20.5 95.6 78.4 86.2 59.9 75.8 15.7 8.3 2.6 29.7 13.8 47.6 20.2 0.0 1.0 2.2 0.0 1.5 0.1 0.4 1.2 0.0 0.0 1.0 1.7 0.0 1.1 0.0 0.0 0.1 0.6 11.9 12.7 12.7 14.3 11.7 13.7 13.9 13.2 13.5 14.2 14.3 14.1 120.3 25.6 36.8 18.9 3.3 60.2 46.8 21.4 50.1 6.0 38.1 26.7 18.2 24.3 31.3 29.5 6.2 37.1 52.9 40.3 3.9 29.6 29.4 32.8 35.0 91.0 22.8 12.0 0.4 39.2 26.6 35.4 57.6 43.6 13.9 35.9 39.7 44.9 4.9 3.3 10.3 37.2 14.2 5.4 14.7 11.7 18.3 5.0 24.9 46.9 2.0 16.8 16.5 31.7 30.2 51.0 28.8 12.8 28.9 65.4 33.1 45.6 29.0 8.6 19.7 35.9 23.8 20.3 13.6 53.1 49.7 45.6 27.5 42.4 36.7 66.6 YTHDC1 "KIAA1966, YT521, YT521-B" ENSG00000083896 "YTH domain containing 1" Q96MU7 4 68310387-68350090 "Plasma proteins, Predicted intracellular proteins" "mRNA processing, mRNA splicing" RNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA036462 Supported Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 1: Neutrophils - Mixed function" "Cluster 75: Bone marrow - mRNA splicing & Cell cycle" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 44: Endometrium - Transcription" Nucleoplasm "Plasma membrane" "HPA036462: AB_10669793" "unprognostic (1.02e-1)" "unprognostic (8.44e-3)" "unprognostic (5.74e-3)" "unprognostic (1.35e-1)" "unprognostic (7.59e-2)" "unprognostic (1.33e-3)" "unprognostic (1.52e-3)" "unprognostic (8.28e-2)" "unprognostic (1.38e-1)" "unprognostic (1.09e-1)" "unprognostic (2.35e-2)" "unprognostic (1.41e-2)" "unprognostic (6.64e-3)" "unprognostic (1.63e-2)" "unprognostic (1.70e-1)" "unprognostic (4.05e-1)" "prognostic favorable (7.29e-5)" 43.0 27.0 22.4 19.5 26.5 116.6 43.8 31.9 25.0 52.6 18.6 40.0 15.6 43.6 22.7 48.0 42.3 15.3 34.1 20.9 26.0 38.2 33.1 40.6 28.4 23.6 23.6 68.6 44.5 20.3 41.2 23.8 24.8 37.9 19.6 38.5 42.1 17.6 47.2 51.3 40.5 17.2 23.2 41.9 36.3 31.3 23.1 30.3 42.1 16.7 26.7 37.3 50.5 32.7 31.8 18.4 37.1 22.2 21.7 18.8 30.4 33.8 21.3 20.6 21.5 22.9 27.9 50.8 27.0 17.2 16.7 23.3 35.1 29.4 33.1 38.2 21.3 38.8 27.3 25.6 22.1 41.5 29.0 17.8 31.3 18.5 44.0 26.6 22.6 24.7 37.5 29.0 30.7 23.9 48.9 37.1 27.6 30.4 18.0 42.4 41.6 22.8 32.6 35.6 31.9 24.8 29.5 31.5 25.9 34.3 24.6 28.8 24.1 23.5 24.9 16.4 22.5 30.1 21.8 53.7 15.9 26.6 22.0 69.3 20.3 40.4 24.1 12.7 19.0 36.1 19.6 19.8 12.2 44.8 26.9 22.9 105.4 20.8 27.0 39.3 20.3 9.7 22.4 26.5 31.9 25.0 20.9 26.0 23.6 23.6 24.8 23.2 23.1 32.7 104.6 112.2 129.5 54.9 104.7 119.9 103.6 76.2 88.8 105.8 112.8 107.2 92.6 85.8 125.1 73.5 70.9 73.6 136.8 58.1 52.8 70.2 98.5 131.9 135.3 92.2 85.8 74.7 43.8 57.2 124.8 81.3 54.0 254.8 94.7 86.2 63.5 85.6 43.2 90.9 49.4 77.9 63.1 61.0 75.9 22.0 74.6 84.5 64.0 56.2 67.0 99.2 96.8 59.3 110.1 81.6 56.0 67.7 103.2 121.6 42.0 44.0 113.2 138.4 52.6 122.0 98.8 139.2 95.9 127.1 134.5 119.0 122.0 59.5 66.9 119.8 ZBED3 MGC15435 ENSG00000132846 "Zinc finger BED-type containing 3" Q96IU2 5 77072072-77087285 "Predicted intracellular proteins, Predicted secreted proteins, Transcription factors" "Wnt signaling pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Hepatocytes: 31.8" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in many" "AN3-CA: 29.7;JURKAT: 31.0;MOLT-4: 29.4" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA055995 Approved Approved "Nucleoplasm,Plasma membrane" "Secreted to blood" NA NA "Cluster 21: Non-specific - Transcription" "Cluster 22: JURKAT & MOLT-4 - Adaptive immune response" "Cluster 40: Granulosa cells - Unknown function" "Plasma membrane" Nucleoplasm "HPA055995: AB_2683000" "unprognostic (3.23e-2)" "unprognostic (1.17e-1)" "unprognostic (2.24e-2)" "unprognostic (1.22e-1)" "unprognostic (3.78e-2)" "unprognostic (4.02e-2)" "unprognostic (2.97e-1)" "unprognostic (1.45e-2)" "unprognostic (6.96e-3)" "unprognostic (1.82e-2)" "unprognostic (8.64e-3)" "unprognostic (3.63e-1)" "prognostic favorable (1.68e-4)" "unprognostic (2.08e-1)" "unprognostic (1.92e-1)" "unprognostic (5.41e-2)" "unprognostic (1.08e-1)" 10.3 3.3 9.3 1.9 14.2 2.6 8.8 9.4 10.8 6.7 7.5 4.2 3.9 10.2 7.4 2.4 7.0 3.5 4.6 7.8 9.2 10.0 10.7 5.0 1.9 16.0 12.2 7.9 7.6 8.4 3.9 2.4 10.9 5.1 4.3 3.8 6.0 6.6 2.7 2.6 3.3 8.7 9.9 3.6 6.4 1.9 13.5 4.8 11.2 3.8 1.9 3.0 3.7 17.1 5.2 4.2 5.4 29.7 22.1 1.5 0.3 1.7 5.0 2.6 6.9 9.1 2.4 0.0 10.9 3.4 1.1 0.6 2.9 1.8 2.3 1.7 5.8 4.0 9.1 10.4 13.1 5.5 1.5 24.6 6.8 1.3 5.1 4.2 8.3 31.0 0.0 11.0 1.6 5.2 29.4 0.8 3.5 1.4 2.5 12.1 10.3 1.7 12.3 2.0 5.9 12.4 6.1 5.0 8.7 2.1 7.5 3.8 3.3 2.3 4.5 5.1 7.0 8.0 8.2 11.5 3.6 10.4 5.4 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.1 0.1 0.0 0.0 0.0 0.2 0.0 0.0 9.3 14.2 9.4 10.8 7.8 9.2 16.0 12.2 10.9 9.9 13.5 17.1 10.5 0.0 2.8 8.1 1.7 1.3 3.8 0.3 4.0 8.4 13.5 13.6 10.7 12.8 2.0 12.9 12.5 1.5 2.0 3.1 17.6 4.1 3.3 16.5 13.5 11.7 16.2 5.0 3.3 6.0 0.3 9.3 11.7 12.5 1.3 20.2 12.1 31.8 9.6 3.3 8.5 5.3 0.0 13.6 4.9 2.2 17.7 9.0 7.2 5.6 5.1 13.8 3.1 16.1 18.3 2.7 3.4 11.3 1.4 5.6 1.9 17.2 0.1 17.0 0.0 21.4 7.7 1.5 3.4 2.2 1.4 0.3 1.2 25.6 7.1 1.8 ZDHHC20 "DHHC20, FLJ25952" ENSG00000180776 "Zinc finger DHHC-type palmitoyltransferase 20" Q5W0Z9 13 21372571-21459370 "Enzymes, Metabolic proteins, Predicted membrane proteins, Transporters" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enhanced" "Detected in many" "brain: 95.0" "Cell type enriched" "Detected in many" 4 "Oligodendrocytes: 434.3" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA014483, HPA014702" Approved Supported "Vesicles,Plasma membrane" NA NA "Cluster 25: Monocytes - Inflammatory response" "Cluster 70: Brain - Nervous system development" "Cluster 42: Epithelial cell lines - Epithelial cell function" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Vesicles, Plasma membrane" "HPA014483: AB_1859000, HPA014702: AB_1859001" "unprognostic (1.31e-1)" "unprognostic (2.16e-3)" "unprognostic (7.31e-3)" "unprognostic (8.89e-2)" "unprognostic (3.37e-2)" "unprognostic (1.03e-1)" "unprognostic (1.06e-3)" "unprognostic (3.77e-1)" "unprognostic (1.24e-2)" "unprognostic (1.26e-2)" "prognostic unfavorable (6.55e-4)" "unprognostic (1.10e-1)" "prognostic unfavorable (1.01e-4)" "unprognostic (3.76e-2)" "unprognostic (7.65e-2)" "unprognostic (6.15e-2)" "unprognostic (1.13e-2)" 10.9 9.2 15.2 17.6 52.9 30.0 11.5 51.8 23.3 16.2 0.0 16.9 19.3 13.8 9.6 30.2 10.9 17.1 7.9 12.0 27.0 6.7 9.8 17.0 18.0 70.8 40.7 9.7 9.0 8.9 4.4 18.8 60.3 15.1 16.1 5.6 8.5 12.2 4.0 22.1 19.0 15.2 35.1 16.1 39.5 31.7 40.7 22.6 16.4 9.4 19.5 22.9 9.3 95.0 32.9 16.4 27.7 18.1 24.5 26.7 68.3 35.6 36.3 23.3 20.6 33.8 102.5 34.8 19.3 44.7 23.8 52.7 30.5 26.5 44.8 40.0 20.4 61.8 11.7 19.6 14.1 43.3 25.8 24.2 19.4 23.6 16.2 30.0 37.6 45.9 17.3 14.9 35.3 27.2 62.0 17.2 22.9 87.3 18.0 49.8 49.1 12.7 28.9 59.7 25.2 11.4 46.0 28.7 19.3 28.6 27.0 21.8 62.6 25.0 24.0 41.7 27.4 15.6 19.9 37.7 18.2 23.6 73.1 12.6 16.2 3.8 10.1 14.9 9.3 4.6 8.7 8.7 8.4 3.4 8.1 8.4 3.0 11.2 13.8 4.1 10.4 13.5 15.2 52.9 51.8 23.3 12.0 27.0 70.8 40.7 60.3 35.1 40.7 95.0 27.6 51.3 31.5 29.0 19.9 1.0 7.8 1.4 18.2 7.4 21.9 13.7 7.4 14.3 20.7 11.0 8.4 20.7 34.7 35.5 0.0 8.5 91.3 23.4 25.2 25.7 24.0 8.4 69.1 12.2 20.9 13.6 53.0 34.5 14.0 16.1 20.0 20.8 21.7 18.5 80.0 29.1 2.0 92.5 3.2 81.2 15.5 49.0 1.8 46.9 48.4 3.7 30.9 54.8 434.3 22.8 25.5 10.9 18.1 14.5 30.3 6.3 11.7 9.5 19.7 12.7 11.6 10.4 14.1 28.1 1.6 44.6 28.4 9.7 25.1 25.6 ZDHHC5 "DHHC5, KIAA1748, ZNF375" ENSG00000156599 "Zinc finger DHHC-type palmitoyltransferase 5" Q9C0B5 11 57667747-57701182 "Enzymes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins, Predicted membrane proteins" "Acyltransferase, Transferase" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA014670 Approved Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 15: RT4 - Unknown function" "Cluster 46: Photoreceptor cells - Phototransduction" "Plasma membrane" Nucleoplasm "HPA014670: AB_2257442" "unprognostic (1.34e-1)" "unprognostic (3.47e-2)" "unprognostic (2.51e-1)" "unprognostic (2.29e-1)" "unprognostic (5.32e-2)" "unprognostic (1.70e-2)" "unprognostic (9.82e-3)" "unprognostic (1.74e-3)" "unprognostic (4.36e-2)" "unprognostic (9.78e-2)" "prognostic unfavorable (6.74e-5)" "unprognostic (1.76e-1)" "unprognostic (4.72e-3)" "unprognostic (2.16e-1)" "unprognostic (6.80e-2)" "unprognostic (2.06e-2)" "unprognostic (1.74e-3)" 29.0 21.7 8.3 27.2 7.8 29.2 25.8 8.3 9.5 27.0 11.0 36.4 29.6 22.3 24.1 60.9 25.0 27.9 27.9 7.5 9.2 28.2 36.7 29.0 24.4 8.5 8.9 20.7 31.6 45.3 12.6 36.7 8.7 28.0 34.4 35.9 35.0 26.7 40.9 45.2 31.0 29.0 6.9 25.5 30.2 36.2 10.9 30.6 36.9 45.5 35.0 42.3 28.7 8.9 80.3 86.2 33.7 34.7 74.9 57.4 64.9 72.8 89.8 61.8 46.3 52.3 97.0 53.4 91.9 89.5 53.1 110.1 53.6 88.9 55.4 66.5 24.4 45.8 40.1 49.3 81.5 85.9 73.7 81.3 79.3 88.8 92.9 51.1 71.0 45.6 61.5 66.2 79.7 48.4 49.1 29.3 41.1 61.0 52.2 47.8 66.6 67.1 74.8 115.2 25.3 30.7 67.6 77.0 78.5 45.4 81.9 52.6 80.7 76.5 40.7 82.9 52.2 48.2 63.0 45.9 59.1 44.4 68.0 11.6 5.2 7.1 6.9 6.8 8.3 5.8 6.7 6.0 5.4 5.7 6.7 6.9 6.9 5.0 8.1 9.0 7.0 6.8 8.3 7.8 8.3 9.5 7.5 9.2 8.5 8.9 8.7 6.9 10.9 8.9 28.8 16.0 10.5 14.7 13.4 16.2 12.7 13.7 16.5 21.4 20.4 15.2 21.6 12.8 19.8 12.9 37.5 10.1 20.3 41.3 3.9 14.4 21.3 19.9 22.1 17.1 11.5 10.8 16.4 18.2 9.9 15.5 15.8 35.5 19.7 24.9 16.1 15.1 13.0 13.5 17.9 17.5 18.3 16.3 10.2 9.8 11.8 18.4 1.8 14.0 16.0 14.0 17.5 17.6 14.7 26.0 20.8 7.5 12.4 15.1 22.9 11.4 17.4 47.7 0.0 18.4 18.5 13.3 7.1 31.5 19.9 18.6 15.9 16.8 19.7 20.5 ZGPAT "dJ583P15.3, FLJ14972, GPATC6, GPATCH6, KIAA1847, MGC44880, ZC3H9, ZC3HDC9, ZIP" ENSG00000197114 "Zinc finger CCCH-type and G-patch domain containing" Q8N5A5 20 63707465-63736142 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Tissue enriched" "Detected in all" 6 "liver: 123.5" "Cell type enhanced" "Detected in many" "Basal squamous epithelial cells: 14.2;Gastric mucus-secreting cells: 13.7;Plasma cells: 26.9;Squamous epithelial cells: 11.1;T-cells: 8.9" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA056705 Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 85: Liver - Metabolism" "Cluster 39: CACO-2 - Unknown function" "Cluster 59: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA056705: AB_2683213" "unprognostic (4.50e-2)" "unprognostic (2.74e-1)" "unprognostic (5.30e-2)" "unprognostic (4.42e-2)" "unprognostic (8.58e-2)" "prognostic favorable (6.17e-5)" "unprognostic (1.06e-1)" "unprognostic (6.97e-2)" "unprognostic (2.52e-1)" "unprognostic (1.54e-1)" "unprognostic (9.31e-3)" "unprognostic (1.60e-2)" "unprognostic (3.43e-3)" "unprognostic (1.37e-1)" "unprognostic (4.11e-2)" "unprognostic (1.24e-1)" "unprognostic (9.86e-3)" 14.5 17.0 5.3 8.8 5.8 14.8 14.6 5.4 8.9 15.7 7.5 18.0 10.0 16.1 3.4 16.6 14.2 5.5 16.0 5.6 4.7 22.2 123.5 13.0 11.5 7.6 5.4 11.9 14.0 8.4 14.4 6.5 5.9 14.9 3.0 1.4 13.7 6.7 16.7 19.0 14.8 4.9 4.1 20.3 15.3 20.2 5.7 9.5 13.8 4.3 4.1 15.9 15.0 7.4 15.3 19.3 7.4 12.0 6.0 4.2 17.1 15.5 10.1 24.0 10.0 41.6 20.4 15.6 28.9 8.8 23.3 27.4 5.0 18.3 3.0 10.7 13.3 14.8 16.9 43.3 11.7 9.4 25.2 10.7 15.3 9.9 3.9 6.5 13.2 18.5 16.5 13.9 8.0 15.3 22.6 22.1 12.1 22.3 24.0 23.9 5.7 15.7 13.5 14.0 14.0 17.4 22.1 24.7 14.2 3.7 16.9 26.0 15.2 37.2 13.3 14.3 20.1 13.9 24.3 22.2 23.5 9.3 17.0 8.6 21.0 26.5 28.3 21.5 28.1 19.2 24.6 26.3 19.7 16.2 23.9 24.7 21.8 26.4 18.4 28.2 26.2 18.6 5.3 5.8 5.4 8.9 5.6 4.7 7.6 5.4 5.9 4.1 5.7 7.4 0.3 3.2 3.4 4.6 8.0 0.0 0.0 0.1 14.2 1.0 0.2 0.3 0.3 0.0 1.3 0.0 0.0 0.2 0.7 0.4 0.0 0.1 0.1 0.4 1.1 2.1 1.8 6.3 7.4 0.2 0.3 3.3 13.7 0.6 2.5 0.5 0.4 2.3 0.2 0.0 5.8 0.2 0.0 1.3 0.0 0.0 0.0 5.4 1.8 8.4 0.0 0.2 0.0 5.5 4.6 0.4 0.1 0.0 26.9 0.2 0.3 0.5 0.1 1.1 0.0 0.5 1.4 0.3 0.1 11.1 0.3 0.3 8.9 0.5 0.2 0.1 ZMYND10 "BLU, CILD22, DNAAF7" ENSG00000004838 "Zinc finger MYND-type containing 10" O75800 3 50341110-50345732 "Disease related genes, Human disease related genes, Plasma proteins, Predicted intracellular proteins" "Ciliopathy, Disease variant, Kartagener syndrome, Primary ciliary dyskinesia" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in many" 6 "fallopian tube: 120.2;testis: 258.5" "Group enriched" "Detected in many" 11 "Early spermatids: 309.4;Endometrial ciliated cells: 221.8;Late spermatids: 415.3;Respiratory ciliated cells: 390.8;Spermatocytes: 529.7" "Cancer enhanced" "Detected in many" "endometrial cancer: 12.6" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.1" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in some" "T-47d: 5.6;U-87 MG: 3.9" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" HPA035255 Approved "Plasma membrane,Cytosol" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 49: Ciliated cells - Cilium organization" "Cluster 6: T47d - Mammary gland" "Cluster 49: Ciliated cells - Cilium organization" "Plasma membrane" Cytosol "HPA035255: AB_10601928" "unprognostic (2.93e-3)" "unprognostic (2.98e-3)" "unprognostic (1.15e-2)" "unprognostic (3.85e-3)" "unprognostic (4.44e-1)" "unprognostic (7.78e-3)" "unprognostic (4.71e-2)" "unprognostic (6.13e-2)" "unprognostic (1.15e-2)" "unprognostic (1.33e-1)" "unprognostic (3.12e-2)" "unprognostic (6.73e-2)" "prognostic favorable (6.75e-5)" "unprognostic (8.25e-2)" "unprognostic (1.26e-1)" "unprognostic (1.16e-1)" "unprognostic (1.18e-1)" 0.3 0.1 5.0 0.2 5.0 0.7 1.1 3.5 2.8 4.3 29.2 0.2 0.2 1.7 1.6 0.2 120.2 0.5 0.2 4.3 6.7 2.1 0.9 11.1 0.2 12.5 15.6 0.6 1.1 3.7 5.9 0.1 9.4 0.7 0.1 3.2 0.3 0.4 0.4 0.5 0.4 0.5 10.4 0.6 0.3 258.5 7.3 0.5 1.9 0.2 0.1 0.2 0.3 9.2 1.6 0.6 0.2 0.5 0.6 0.9 0.3 0.2 0.9 1.6 0.5 0.0 1.0 0.7 0.6 1.0 0.2 0.2 1.5 0.0 0.1 0.4 0.6 1.5 1.2 0.0 0.0 0.5 0.8 0.0 0.1 2.0 0.1 1.5 0.1 1.3 0.5 0.1 0.2 1.0 0.3 2.7 0.0 0.2 0.7 0.7 0.0 0.5 2.0 0.0 1.8 0.5 0.1 0.5 0.0 0.0 5.6 0.6 0.0 0.3 0.4 0.9 0.1 1.0 0.4 0.1 3.9 2.2 0.1 0.0 0.0 0.0 0.6 0.1 0.2 0.0 0.0 0.0 0.2 0.0 0.0 0.0 0.1 1.1 0.1 0.0 0.0 0.1 5.0 5.0 3.5 2.8 4.3 6.7 12.5 15.6 9.4 10.4 7.3 9.2 0.5 3.2 5.1 1.3 0.7 0.5 0.4 24.2 1.2 1.2 2.3 1.7 0.8 0.0 33.1 1.8 4.2 0.1 1.7 0.2 0.0 1.1 309.4 221.8 2.4 1.2 0.0 3.2 0.5 0.0 0.2 1.1 0.0 3.6 0.0 0.3 0.7 0.4 0.6 0.0 0.3 0.7 22.4 0.0 0.4 415.3 9.0 1.3 1.8 1.0 0.9 1.2 2.1 0.5 1.3 0.1 0.0 5.7 0.9 0.6 0.0 1.0 390.8 7.6 0.0 0.9 9.8 529.7 9.1 1.1 0.4 0.1 1.7 0.2 0.3 0.1 ZNF20 KOX13 ENSG00000132010 "Zinc finger protein 20" P17024 19 12092843-12140355 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Group enriched" "Detected in many" 4 "Early spermatids: 42.1;Late spermatids: 66.3;Respiratory ciliated cells: 29.7" "Not detected" "Not detected" "Low region specificity" "Detected in many" "Immune cell enhanced" "Detected in all" "neutrophil: 22.9" "Group enriched" "Detected in all" 5 "granulocytes: 22.9;NK-cells: 6.8" "Low cell line specificity" "Detected in many" HPA020887 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 6: Non-specific - Transcription" "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 34: Spermatids - Unknown function" "Plasma membrane" Nucleoplasm "HPA020887: AB_2218842" "unprognostic (1.77e-2)" "unprognostic (1.06e-2)" "unprognostic (1.69e-2)" "unprognostic (1.20e-3)" "unprognostic (4.00e-2)" "unprognostic (1.08e-4)" "unprognostic (1.69e-1)" "unprognostic (2.14e-2)" "unprognostic (1.57e-3)" "unprognostic (1.04e-1)" "unprognostic (4.40e-2)" "unprognostic (7.01e-2)" "unprognostic (9.23e-2)" "unprognostic (1.21e-1)" "unprognostic (1.50e-2)" "unprognostic (1.15e-2)" "unprognostic (1.21e-3)" 0.8 1.2 0.9 1.6 0.9 2.7 3.0 2.1 1.3 1.3 2.3 2.0 0.7 1.2 3.1 2.0 4.9 1.2 0.8 0.9 0.7 1.8 0.8 1.6 2.1 0.9 1.1 1.8 2.1 1.8 1.2 0.9 0.9 1.3 1.8 1.9 2.2 1.5 0.3 2.4 1.4 1.0 0.8 1.3 2.1 6.1 0.7 1.5 3.4 1.1 1.3 1.5 1.2 1.3 2.4 0.0 3.1 6.8 1.2 2.4 2.4 1.6 3.3 1.7 2.4 0.8 0.9 1.8 1.9 2.2 1.7 1.4 1.6 0.5 2.0 1.7 0.6 0.4 2.4 0.8 0.7 0.0 2.2 1.9 3.3 0.8 1.0 2.0 1.3 3.7 1.0 0.3 3.9 0.9 3.0 2.2 5.4 1.2 1.7 2.0 1.6 1.0 2.1 5.4 1.2 3.2 1.6 1.4 2.9 3.0 2.3 3.0 0.0 4.1 1.3 4.3 1.1 3.4 2.0 2.2 0.4 0.0 1.6 16.3 2.5 6.5 1.4 1.3 1.2 1.6 1.4 1.6 1.3 2.6 1.3 1.1 22.9 6.8 1.9 1.7 3.2 1.2 0.9 0.9 2.1 1.3 0.9 0.7 0.9 1.1 0.9 0.8 0.7 1.3 0.4 0.0 0.0 0.0 1.0 0.1 0.8 2.3 1.8 0.6 1.8 1.1 0.8 1.5 1.5 1.8 2.1 1.0 0.9 1.9 1.9 2.1 42.1 10.3 0.7 0.7 4.2 1.7 0.0 2.4 1.3 0.5 3.6 1.4 2.5 0.8 0.4 2.3 1.7 0.0 0.0 2.1 0.0 0.8 1.0 66.3 0.6 1.0 0.0 0.0 1.4 0.4 1.0 0.0 0.0 2.7 2.1 0.0 1.5 1.7 2.9 2.9 29.7 1.4 0.0 0.4 1.0 10.8 1.7 1.8 0.6 1.1 1.2 0.3 1.7 1.6 ZNF229 ENSG00000278318 "Zinc finger protein 229" Q9UJW7 19 44417519-44448578 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in many" "Oligodendrocyte precursor cells: 7.5;Rod photoreceptor cells: 6.9" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Immune cell enhanced" "Detected in single" "NK-cell: 1.5" "Low lineage specificity" "Detected in single" "Cell line enhanced" "Detected in many" "hTERT-HME1: 6.9" HPA001494 Uncertain Approved "Vesicles,Plasma membrane" NA NA "Cluster 15: NK-cells - Transcription" "Cluster 77: Retina - Visual perception" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" Vesicles "Plasma membrane" "HPA001494: AB_1080692" "unprognostic (2.59e-1)" "unprognostic (7.41e-4)" "unprognostic (2.13e-1)" "unprognostic (1.08e-1)" "unprognostic (3.90e-1)" "unprognostic (2.17e-1)" "unprognostic (3.34e-2)" "unprognostic (7.18e-3)" "unprognostic (1.17e-2)" "unprognostic (4.66e-2)" "unprognostic (4.18e-2)" "unprognostic (5.04e-3)" "prognostic favorable (8.43e-5)" "unprognostic (3.66e-3)" "unprognostic (2.01e-2)" "unprognostic (2.18e-1)" "unprognostic (4.34e-1)" 0.5 1.7 1.3 0.1 1.4 0.1 1.0 1.3 1.6 1.0 1.7 0.9 0.7 1.1 1.1 0.7 1.9 0.5 1.4 1.4 1.4 0.8 0.7 0.6 0.3 1.3 1.3 2.3 0.8 2.7 1.3 1.1 1.3 1.2 0.1 4.5 0.7 0.8 0.8 0.3 0.4 0.8 1.2 0.6 0.6 0.7 1.5 1.1 2.0 1.2 0.3 0.8 0.5 1.6 0.0 3.7 2.7 0.0 2.9 2.4 0.0 4.4 1.4 2.1 2.8 0.0 0.6 0.0 1.7 2.5 3.4 1.3 0.0 2.8 1.4 0.0 1.4 0.4 1.2 0.3 5.0 0.0 0.0 3.4 0.0 1.7 6.9 2.9 2.0 0.0 0.1 0.0 3.0 0.0 0.0 0.0 3.4 0.0 1.0 0.0 0.0 1.3 2.1 5.5 0.7 1.0 1.9 0.3 0.0 2.0 0.0 0.0 1.9 1.3 0.1 0.5 0.1 3.1 2.1 0.0 0.0 0.0 2.7 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.1 0.4 0.3 0.1 0.0 1.5 0.0 0.0 0.0 0.1 1.3 1.4 1.3 1.6 1.4 1.4 1.3 1.3 1.3 1.2 1.5 1.6 1.4 0.0 0.0 5.9 0.4 0.1 0.7 2.0 1.8 5.8 2.1 2.2 3.7 0.0 1.3 0.0 4.2 0.9 0.0 0.2 3.9 1.7 0.7 1.6 1.7 1.3 0.0 2.1 3.1 1.2 0.6 1.0 2.6 1.0 0.0 3.4 1.4 0.2 0.7 1.7 4.5 0.3 0.0 0.6 0.0 0.5 0.9 0.3 0.0 1.0 0.1 4.7 0.0 7.5 2.2 2.0 0.3 1.9 0.0 1.6 0.3 1.6 4.5 6.9 0.0 1.0 1.5 1.8 2.4 1.4 0.0 0.8 0.2 3.4 0.5 0.9 ZNF277 "NRIF4, ZNF277P" ENSG00000198839 "Zinc finger protein 277" Q9NRM2 7 112206695-112343934 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA027307 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 44: Non-specific - Transcription" "Cluster 29: Non-specific - Vesicular transport" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 32: Non-specific - Translation" Nucleoplasm "Plasma membrane" "HPA027307: AB_1859164" "unprognostic (2.04e-1)" "unprognostic (1.43e-1)" "unprognostic (1.07e-1)" "unprognostic (3.95e-2)" "unprognostic (7.76e-2)" "unprognostic (3.17e-2)" "unprognostic (1.43e-1)" "unprognostic (4.18e-2)" "unprognostic (4.60e-2)" "unprognostic (7.61e-2)" "unprognostic (1.88e-2)" "unprognostic (2.85e-1)" "prognostic favorable (9.47e-4)" "unprognostic (1.05e-1)" "unprognostic (2.64e-2)" "unprognostic (2.46e-1)" "unprognostic (1.06e-1)" 7.5 6.8 3.9 5.4 4.9 6.1 8.9 4.2 7.2 6.1 3.8 7.1 5.9 6.7 3.1 7.1 6.0 6.4 8.0 4.5 3.7 9.5 11.6 7.0 6.8 4.7 3.8 7.1 11.3 7.1 4.6 4.6 4.6 5.6 6.9 4.5 7.1 4.4 6.5 8.3 5.6 6.0 3.8 5.8 7.8 5.4 4.7 7.9 9.4 3.4 6.3 8.2 7.0 7.1 7.6 4.5 7.5 9.3 10.2 28.1 5.6 7.4 7.9 3.5 6.3 6.8 6.8 12.6 13.3 6.1 7.2 5.0 5.7 7.3 9.4 10.2 3.6 6.6 6.1 5.8 6.3 12.1 5.2 17.1 10.8 8.6 5.7 11.1 10.7 13.2 7.9 13.3 6.4 8.8 15.2 20.6 5.1 6.5 5.0 7.4 8.2 11.4 9.5 5.6 5.3 13.8 9.7 12.0 11.9 8.1 3.4 10.2 14.9 5.4 3.1 12.0 4.8 11.5 14.6 14.8 3.9 11.5 6.6 9.3 4.6 6.4 5.7 8.1 8.5 8.7 8.0 8.2 3.7 9.6 9.6 8.1 6.6 7.4 7.2 5.9 9.4 3.7 3.9 4.9 4.2 7.2 4.5 3.7 4.7 3.8 4.6 3.8 4.7 7.1 13.0 38.5 24.6 77.1 25.7 20.6 18.2 35.7 26.2 10.0 19.0 17.5 12.8 27.1 24.1 5.5 2.1 12.3 19.6 12.4 27.4 25.9 46.4 13.6 15.6 17.9 18.5 11.1 51.9 31.0 18.3 15.7 12.8 16.3 7.6 21.4 16.4 19.2 21.7 32.0 43.4 22.5 34.6 46.9 34.8 8.6 17.1 29.1 12.4 43.1 50.6 6.6 37.0 47.7 70.5 24.6 22.9 25.2 13.2 17.5 27.0 34.5 12.7 12.0 19.7 17.1 23.7 32.8 10.4 19.1 24.3 13.8 25.8 28.1 22.4 21.5 ZNF337 dJ694B14.1 ENSG00000130684 "Zinc finger protein 337" Q9Y3M9 20 25673195-25696853 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Astrocytes: 26.4;Excitatory neurons: 30.4;Inhibitory neurons: 26.8;Oligodendrocyte precursor cells: 26.2;Oligodendrocytes: 29.3" "Low cancer specificity" "Detected in many" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "HPA044303, HPA064219" Approved Approved "Nuclear speckles,Plasma membrane" NA NA "Cluster 22: NK-cells - Unknown function" "Cluster 35: Non-specific - Unknown function" "Cluster 30: Epithelial cell lines - Translation" "Cluster 11: Alveolar cells - Smell perception" "Plasma membrane" "Nuclear speckles" "HPA044303: AB_2678890, HPA064219: AB_2685215" "unprognostic (2.14e-1)" "unprognostic (2.19e-2)" "unprognostic (1.65e-2)" "unprognostic (1.80e-1)" "unprognostic (1.30e-1)" "unprognostic (5.81e-3)" "unprognostic (4.54e-3)" "unprognostic (6.99e-2)" "unprognostic (2.34e-1)" "unprognostic (1.34e-2)" "unprognostic (3.15e-2)" "unprognostic (9.36e-4)" "prognostic unfavorable (2.87e-6)" "unprognostic (1.29e-1)" "unprognostic (1.54e-1)" "unprognostic (3.93e-2)" "unprognostic (8.82e-3)" 15.8 13.4 21.5 7.4 21.9 10.3 16.1 28.6 25.5 27.4 23.0 26.5 5.9 21.5 16.1 14.8 26.2 6.9 14.4 20.9 20.6 19.2 11.6 16.6 11.2 20.6 20.3 31.2 13.1 10.4 24.4 7.7 20.5 27.4 8.9 25.9 12.7 13.2 12.5 13.1 18.6 11.7 19.2 21.7 14.0 9.3 20.6 15.3 18.8 8.6 9.5 22.4 19.7 25.3 10.0 17.3 14.0 9.9 11.2 14.3 11.9 8.4 7.3 6.3 7.8 3.6 9.1 12.3 7.8 7.8 12.8 16.0 9.3 27.9 8.7 4.4 7.2 7.5 13.9 15.8 9.6 6.9 8.1 13.3 24.1 7.5 22.1 16.7 10.0 15.7 6.8 10.6 12.5 11.4 18.6 13.4 3.7 5.3 12.2 11.8 12.8 6.0 6.6 11.1 11.2 12.0 8.3 13.4 11.1 17.2 7.7 9.4 13.5 14.1 7.2 9.4 11.3 14.9 8.3 4.3 6.7 5.9 11.2 0.0 1.6 3.2 4.6 2.7 5.0 2.3 3.7 4.2 2.7 1.8 5.2 6.1 0.0 3.9 1.5 2.5 2.5 2.6 21.5 21.9 28.6 25.5 20.9 20.6 20.6 20.3 20.5 19.2 20.6 25.3 8.6 6.4 15.4 26.4 4.3 2.0 5.6 3.4 4.6 8.4 4.1 5.2 1.2 2.8 10.8 3.7 2.1 3.8 4.5 1.2 3.9 4.3 1.4 6.7 8.9 5.6 5.4 1.3 30.4 3.1 2.0 5.4 2.0 4.4 5.1 9.8 3.3 3.2 3.3 6.7 26.8 4.2 0.0 3.1 1.1 0.3 7.2 4.3 1.8 25.3 3.1 7.9 11.3 26.2 29.3 2.7 1.0 5.7 1.7 5.4 1.6 1.9 15.5 13.0 0.0 6.3 4.8 8.1 10.2 3.6 2.4 2.3 6.2 5.4 2.6 1.9 ZNF366 FLJ39796 ENSG00000178175 "Zinc finger protein 366" Q8N895 5 72439903-72507410 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" "DNA-binding, Repressor" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in many" "Cell type enhanced" "Detected in some" "Adipocytes: 19.0;Cone photoreceptor cells: 31.3;Endothelial cells: 18.3;Langerhans cells: 9.3;Microglial cells: 54.4;monocytes: 14.5" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in all" "Immune cell enriched" "Detected in some" 9 "myeloid DC: 10.4" "Lineage enriched" "Detected in many" 9 "dendritic cells: 10.4" "Cell line enhanced" "Detected in some" "HUVEC TERT2: 1.3;TIME: 1.8" "Low region specificity" "Detected in many" "Low region specificity" "Detected in all" "HPA023128, HPA023526, HPA074074" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 28: Myeloid DCs - Unknown function" "Cluster 57: Non-specific - Angiogenesis" "Cluster 41: TIME & HUVEC/TERT2 - Endothelial cell function" "Cluster 14: Adipocytes & Endothelial cells - Angiogenesis" Nucleoplasm "Plasma membrane" "HPA023128: AB_1859223, HPA023526: AB_1859224, HPA074074: " "unprognostic (3.49e-1)" "unprognostic (8.44e-2)" "unprognostic (2.44e-1)" "unprognostic (2.27e-1)" "unprognostic (6.17e-2)" "unprognostic (1.95e-3)" "unprognostic (9.25e-2)" "unprognostic (6.67e-2)" "unprognostic (1.43e-1)" "unprognostic (2.47e-1)" "unprognostic (1.34e-1)" "unprognostic (1.27e-1)" "unprognostic (1.88e-3)" "unprognostic (1.53e-1)" "unprognostic (1.61e-1)" "unprognostic (1.43e-1)" "unprognostic (6.29e-2)" 5.8 0.8 6.1 3.4 5.0 0.1 3.2 4.5 5.6 2.8 2.4 1.4 1.5 3.1 0.7 1.8 2.4 2.3 3.8 4.1 4.6 2.1 1.0 2.6 5.0 5.8 5.5 0.8 0.7 1.1 0.4 8.9 6.0 0.9 1.5 0.5 0.8 1.5 5.0 2.2 1.9 3.9 4.1 6.4 1.4 0.5 7.1 3.1 2.2 5.6 4.0 1.7 1.0 4.5 0.0 0.7 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.3 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 1.3 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.7 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.8 0.2 0.0 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 1.1 0.0 0.0 0.4 0.0 0.0 0.0 0.0 10.4 0.0 0.0 0.0 0.2 0.0 0.0 0.3 0.0 0.5 6.1 5.0 4.5 5.6 4.1 4.6 5.8 5.5 6.0 4.1 7.1 4.5 19.0 0.0 0.6 0.0 0.1 0.5 0.4 0.0 0.6 0.4 0.1 0.3 1.6 0.0 0.6 0.0 31.3 0.0 0.1 0.0 0.0 0.0 0.3 0.0 0.0 18.3 0.0 0.0 0.4 0.0 0.0 0.6 0.0 0.0 0.0 0.0 6.8 0.4 0.5 0.0 0.3 0.0 0.0 4.6 9.3 0.5 0.3 2.4 0.0 54.4 14.5 0.1 0.0 0.5 0.3 0.0 0.0 0.0 0.1 0.2 0.0 0.0 0.0 0.8 0.0 1.2 0.7 0.0 0.0 0.2 0.3 0.1 0.3 0.1 0.0 0.0 ZNF407 "FLJ13839, FLJ20307, KIAA1703" ENSG00000215421 "Zinc finger protein 407" Q9C0G0 18 74597870-75065671 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Group enriched" "Detected in many" 5 "Astrocytes: 96.9;Excitatory neurons: 111.0;Inhibitory neurons: 100.2;Microglial cells: 113.4;Oligodendrocyte precursor cells: 122.6;Oligodendrocytes: 130.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA028255, HPA041673" Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 76: Brain & Bone marrow - Chromatin organization" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 42: Oligodendrocytes - Myelin sheath organization" "Nucleoplasm, Plasma membrane" "HPA028255: AB_10603466, HPA041673: AB_2677610" "unprognostic (3.96e-1)" "unprognostic (1.95e-1)" "unprognostic (2.48e-1)" "unprognostic (8.62e-2)" "unprognostic (4.61e-2)" "unprognostic (2.09e-2)" "unprognostic (1.76e-2)" "unprognostic (4.31e-1)" "unprognostic (1.19e-3)" "unprognostic (4.04e-4)" "unprognostic (3.47e-2)" "unprognostic (2.22e-1)" "prognostic favorable (9.79e-5)" "unprognostic (8.87e-2)" "unprognostic (3.07e-1)" "unprognostic (1.24e-1)" "unprognostic (3.11e-2)" 2.4 1.9 2.9 3.1 3.5 5.3 2.9 8.0 2.8 2.7 8.6 2.8 2.2 3.7 1.9 2.5 2.7 2.1 3.2 2.3 2.9 2.4 2.2 2.4 3.3 3.6 3.0 4.8 2.2 3.9 1.5 2.7 4.1 2.8 2.2 2.9 2.4 2.8 3.9 2.3 2.4 3.1 2.9 3.4 2.3 4.0 3.2 5.5 3.6 3.6 3.0 2.4 2.0 4.1 3.9 4.0 4.4 4.1 3.2 4.7 3.2 5.1 4.4 3.7 4.0 1.7 2.2 5.6 1.5 7.1 2.5 4.5 4.2 5.5 5.4 9.3 2.6 7.1 5.5 3.2 2.9 10.9 6.0 4.3 2.4 5.9 5.1 3.5 5.6 3.9 4.1 8.0 5.7 3.1 5.3 1.5 2.6 1.4 3.6 5.4 5.8 4.4 2.6 7.2 4.2 4.0 4.7 2.9 3.6 3.2 3.4 4.6 7.9 8.3 3.5 2.3 4.1 2.8 6.2 5.7 3.0 4.6 5.0 1.6 0.7 0.9 1.0 0.9 1.0 0.8 0.8 0.6 0.3 0.8 0.9 1.1 2.2 1.1 0.6 1.3 0.2 0.4 2.9 3.5 8.0 2.8 2.3 2.9 3.6 3.0 4.1 2.9 3.2 4.1 16.5 6.4 6.3 96.9 10.6 3.2 5.0 3.0 2.8 11.2 6.3 6.0 19.4 2.8 4.9 5.5 6.2 4.2 11.4 6.9 0.0 4.3 4.6 8.6 15.3 10.0 4.2 3.4 111.0 2.9 2.7 7.6 17.3 14.4 1.3 10.2 3.3 5.5 3.2 5.0 100.2 5.7 2.0 5.3 2.8 3.3 5.3 7.6 5.4 113.4 6.1 6.2 8.2 122.6 130.5 4.8 6.0 4.5 11.1 4.4 4.3 2.6 6.2 13.2 6.6 10.8 8.1 9.0 12.8 5.6 4.1 5.2 10.1 12.1 6.0 3.9 ZNF474 "4933409D10Rik, FLJ32921" ENSG00000164185 "Zinc finger protein 474" Q6S9Z5 5 122129546-122153569 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Group enriched" "Detected in some" 5 "brain: 4.2;choroid plexus: 7.1;fallopian tube: 17.1;testis: 7.6" "Group enriched" "Detected in some" 5 "Early spermatids: 23.0;Endometrial ciliated cells: 23.2;Late spermatids: 12.4;Respiratory ciliated cells: 22.0" "Low cancer specificity" "Detected in some" "Low region specificity" "Detected in many" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Cell line enhanced" "Detected in some" "BJ: 1.0;CAPAN-2: 1.1;GAMG: 1.3;TIME: 1.2" "Low region specificity" "Detected in many" HPA036594 Approved "Nuclear membrane,Plasma membrane" NA NA "Cluster 42: Ciliated cells - Cilium & Cell projection" "Cluster 11: RPE1 & U-87MG - Synaptic function" "Cluster 49: Ciliated cells - Cilium organization" "Nuclear membrane" "Plasma membrane" "HPA036594: " "unprognostic (9.98e-2)" "unprognostic (2.13e-1)" "unprognostic (7.42e-2)" "unprognostic (5.90e-3)" "unprognostic (7.82e-2)" "unprognostic (2.49e-2)" "unprognostic (3.94e-2)" "unprognostic (7.61e-2)" "unprognostic (3.14e-2)" "unprognostic (1.13e-1)" "unprognostic (2.06e-1)" "unprognostic (1.06e-2)" "unprognostic (1.51e-3)" "unprognostic (1.12e-3)" "unprognostic (9.74e-2)" "unprognostic (2.20e-1)" "unprognostic (4.09e-4)" 0.2 0.1 0.6 0.1 0.7 0.0 0.2 0.5 0.3 0.6 7.1 0.3 0.1 0.7 0.0 0.4 17.1 0.5 0.1 0.6 1.2 0.3 0.1 1.7 0.0 2.2 4.2 0.2 0.1 0.0 0.2 0.0 2.0 0.2 0.1 0.1 0.1 0.1 0.1 0.2 0.2 0.1 1.7 0.1 0.1 7.6 1.2 0.3 0.9 0.1 0.1 0.1 0.1 1.9 0.0 0.4 0.1 0.0 0.2 0.1 0.0 1.0 0.2 0.1 0.0 0.0 1.1 0.0 0.0 0.7 1.3 0.2 0.0 0.0 0.4 0.1 0.1 0.4 0.2 0.0 0.2 0.3 0.0 0.1 0.5 0.2 0.1 0.2 0.0 0.2 0.0 0.0 0.0 0.6 0.2 0.1 0.0 0.0 0.0 0.3 0.0 0.3 0.1 0.0 0.2 0.0 0.3 0.0 0.1 0.1 0.1 0.1 1.2 0.3 0.2 0.7 0.2 0.1 0.2 0.1 0.8 0.0 0.6 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.6 0.7 0.5 0.3 0.6 1.2 2.2 4.2 2.0 1.7 1.2 1.9 0.1 0.0 0.0 0.0 0.0 0.0 0.1 0.4 0.0 0.0 0.0 0.0 0.1 0.0 4.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 23.0 23.2 0.3 0.4 0.0 0.0 0.0 0.0 0.0 0.4 0.0 0.6 1.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 12.4 0.3 0.1 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.0 0.0 22.0 0.0 0.0 0.1 0.6 2.6 0.1 0.0 0.0 0.0 0.1 0.0 0.0 0.0 ZNF510 KIAA0972 ENSG00000081386 "Zinc finger protein 510" Q9Y2H8 9 96754553-96778129 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Excitatory neurons: 21.5;Inhibitory neurons: 22.7;Oligodendrocytes: 20.5" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" HPA049139 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 77: Retina - Visual perception" "Cluster 31: RH-30 & LHCN-M2 - Muscle contraction" "Cluster 52: Non-specific - Transcription" "Nucleoplasm, Plasma membrane" "HPA049139: AB_2680651" "unprognostic (2.70e-2)" "unprognostic (3.44e-1)" "unprognostic (1.07e-1)" "unprognostic (6.92e-2)" "unprognostic (2.01e-2)" "unprognostic (1.43e-2)" "unprognostic (3.78e-1)" "unprognostic (1.21e-2)" "unprognostic (8.50e-3)" "unprognostic (3.90e-2)" "unprognostic (1.06e-1)" "unprognostic (4.34e-2)" "prognostic favorable (5.94e-4)" "unprognostic (1.02e-2)" "unprognostic (1.17e-1)" "unprognostic (5.17e-2)" "unprognostic (2.18e-2)" 3.6 3.8 4.8 3.3 4.7 2.3 4.8 8.3 6.1 5.2 2.4 3.9 2.6 4.7 3.5 2.7 4.0 2.7 3.6 4.9 5.2 3.8 3.8 3.3 4.3 3.6 4.2 5.7 5.1 5.0 4.6 3.1 3.7 4.3 3.3 11.7 3.3 4.3 4.3 3.4 2.9 4.1 4.0 4.2 3.4 3.3 5.2 5.5 4.7 4.8 4.7 3.7 3.2 5.2 4.2 4.3 8.1 7.2 6.7 6.3 4.0 3.7 6.5 6.1 6.4 3.7 2.7 5.7 2.2 3.7 5.8 8.7 3.2 3.3 5.8 6.5 3.7 6.0 7.0 2.5 3.5 3.5 5.2 4.3 5.8 4.5 6.9 6.5 5.3 8.2 6.8 4.5 7.8 3.9 9.3 5.2 6.6 5.9 3.6 5.6 14.4 2.4 4.3 3.2 9.9 7.8 7.0 3.9 3.8 5.4 3.1 6.2 4.1 4.4 4.5 5.6 5.9 8.8 9.8 3.5 2.7 2.0 4.6 0.4 0.2 0.6 0.7 0.3 1.2 0.9 1.2 0.9 0.2 1.0 1.3 0.9 0.1 1.4 0.8 0.3 0.8 0.4 4.8 4.7 8.3 6.1 4.9 5.2 3.6 4.2 3.7 4.0 5.2 5.2 5.5 3.2 3.2 13.4 4.5 1.7 1.6 1.7 0.6 11.0 2.6 2.5 5.1 1.5 2.9 3.7 2.1 2.2 3.2 1.4 1.9 2.2 5.7 3.5 6.3 4.2 1.2 4.0 21.5 2.6 1.4 5.7 2.0 4.0 1.3 5.7 3.6 1.3 2.0 16.8 22.7 2.1 2.0 2.5 0.5 6.9 5.9 2.2 5.4 10.3 2.0 4.5 8.2 18.1 20.5 1.8 2.8 4.1 3.1 2.0 1.0 1.9 3.2 6.5 6.6 4.6 3.3 3.6 5.6 1.8 1.4 0.8 4.6 4.3 1.5 1.1 ZNF598 "FLJ00086, HEL2" ENSG00000167962 "Zinc finger protein 598, E3 ubiquitin ligase" 16 1997654-2009821 "Predicted intracellular proteins" "Evidence at transcript level" "Evidence at transcript level" "Low tissue specificity" "Detected in many" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Not detected in immune cells" "Not detected" "Not detected" "Not detected" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041760, HPA041896" Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 3: Plasmacytoid DCs - Unknown function" "Cluster 50: Non-specific - Ribosome" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 27: Mucus-secreting cells - Mucin production" "Plasma membrane, Cytosol" "HPA041760: AB_10792490, HPA041896: AB_10796464" "unprognostic (9.43e-2)" "unprognostic (1.34e-2)" "unprognostic (8.17e-2)" "unprognostic (6.76e-3)" "unprognostic (3.44e-1)" "unprognostic (1.20e-1)" "unprognostic (2.22e-2)" "unprognostic (7.07e-3)" "unprognostic (1.22e-1)" "unprognostic (4.45e-2)" "unprognostic (1.43e-1)" "unprognostic (5.06e-2)" "unprognostic (4.69e-2)" "unprognostic (1.78e-1)" "unprognostic (1.02e-1)" "unprognostic (1.81e-2)" "unprognostic (7.81e-2)" 15.0 10.1 2.3 6.8 2.2 11.8 13.9 2.3 5.3 15.4 0.9 14.7 7.0 15.4 0.0 19.4 13.1 2.6 11.6 2.5 2.1 13.1 21.0 15.3 5.5 2.9 2.4 12.4 32.3 2.2 16.3 5.0 2.3 16.2 1.4 0.4 18.7 4.4 26.7 30.0 14.8 2.1 1.7 18.6 14.9 17.6 2.6 5.1 10.8 3.8 2.9 15.8 15.3 2.0 22.8 30.1 7.0 17.5 4.9 6.6 22.0 17.3 7.4 10.5 8.3 31.9 12.4 23.4 20.0 6.7 7.7 27.0 9.3 17.3 1.7 31.2 69.9 18.6 33.5 18.3 22.3 29.3 20.0 7.9 23.2 16.6 18.9 1.1 11.6 27.2 41.3 31.5 4.0 40.5 25.2 45.0 21.6 8.9 35.4 62.4 14.2 52.9 4.0 8.7 33.5 28.9 17.4 20.4 28.3 1.3 14.5 46.6 20.6 23.0 27.6 21.0 32.4 39.2 36.3 29.6 9.7 27.6 20.9 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.0 0.1 0.1 0.0 0.0 0.1 0.3 0.0 0.0 2.3 2.2 2.3 5.3 2.5 2.1 2.9 2.4 2.3 1.7 2.6 2.0 11.7 6.4 11.5 6.2 7.5 29.7 12.9 9.0 10.2 12.8 13.9 12.4 1.0 10.0 8.8 1.8 16.7 9.1 11.1 21.2 0.0 8.1 5.6 10.1 11.6 12.7 11.4 10.8 5.4 26.5 12.8 10.5 36.2 13.7 12.7 11.9 6.8 20.1 9.5 16.8 5.3 36.2 12.2 8.4 10.3 9.7 13.4 8.8 1.8 5.6 8.2 7.8 9.2 1.0 6.7 19.6 9.5 8.2 9.3 23.9 13.5 3.3 12.7 10.7 0.0 11.2 9.1 9.0 11.9 14.0 34.8 9.3 9.8 13.1 20.8 19.7 ZNF655 "VIK, VIK-1" ENSG00000197343 "Zinc finger protein 655" Q8N720 7 99558406-99576453 "Predicted intracellular proteins, Transcription factors" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in all" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in all" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA029534, HPA050750" Uncertain Supported "Nucleoplasm,Plasma membrane" NA NA "Cluster 34: Basophils - Unknown function" "Cluster 24: Salivary gland - Salivary secretion" "Cluster 26: Non-specific - Cell cycle regulation" "Cluster 52: Non-specific - Transcription" Nucleoplasm "Plasma membrane" "HPA029534: AB_10603008, HPA050750: AB_2681225" "prognostic favorable (7.12e-4)" "unprognostic (3.03e-2)" "unprognostic (9.62e-2)" "unprognostic (5.00e-1)" "unprognostic (1.51e-1)" "unprognostic (5.42e-2)" "unprognostic (3.31e-2)" "unprognostic (3.93e-3)" "prognostic unfavorable (7.24e-4)" "unprognostic (2.01e-1)" "unprognostic (1.49e-2)" "unprognostic (1.18e-1)" "unprognostic (1.42e-2)" "unprognostic (2.16e-1)" "unprognostic (2.11e-1)" "unprognostic (1.62e-2)" "unprognostic (1.12e-1)" 11.6 11.9 7.0 14.3 6.2 8.9 12.8 8.3 7.8 13.2 5.9 15.5 15.9 10.1 11.0 26.9 11.5 10.2 8.4 6.3 6.1 13.8 14.9 15.3 19.7 5.0 5.5 13.9 21.1 14.4 8.2 12.5 6.4 11.4 11.8 8.5 16.7 11.3 12.7 18.4 13.8 11.7 5.1 14.2 18.0 7.4 6.3 22.6 11.8 13.5 17.3 18.8 14.9 9.6 40.5 35.9 16.5 23.9 15.8 25.4 12.4 24.0 45.8 40.7 37.8 20.1 37.0 31.8 0.4 33.2 52.0 25.2 18.0 29.6 40.6 34.5 23.6 18.9 16.0 27.8 24.1 38.1 35.9 21.1 32.8 35.8 50.6 21.4 17.3 26.4 54.4 39.7 24.4 0.1 53.9 36.6 21.1 0.1 0.0 19.9 14.0 52.9 25.9 42.8 17.4 37.6 25.1 0.7 27.2 24.0 12.2 20.2 13.3 24.3 60.2 43.4 43.6 47.3 72.7 63.4 23.5 18.2 39.9 147.8 43.2 74.4 47.8 47.2 45.1 32.7 44.1 55.7 40.3 31.3 35.0 43.8 50.3 37.0 55.2 23.3 61.3 55.4 7.0 6.2 8.3 7.8 6.3 6.1 5.0 5.5 6.4 5.1 6.3 9.6 19.5 96.1 82.8 51.2 53.2 44.7 46.5 36.5 42.1 48.8 34.4 25.1 36.1 31.5 44.3 23.9 41.7 31.6 76.3 46.3 33.2 31.6 12.8 25.8 33.9 20.4 41.5 12.8 53.4 36.2 42.7 32.7 37.2 33.0 18.9 70.8 19.2 24.6 37.4 50.5 57.4 40.4 18.3 63.4 31.6 9.7 25.4 56.0 23.2 44.0 59.2 24.9 106.1 61.3 75.3 48.2 55.2 25.2 55.4 44.5 48.1 41.1 26.0 45.8 13.1 39.9 31.7 39.0 29.8 55.6 48.9 73.6 62.5 30.0 28.1 64.0 ZNF783 DKFZp667J212 ENSG00000204946 "Zinc finger family member 783" Q6ZMS7 7 149262171-149297302 "Predicted intracellular proteins" "Transcription, Transcription regulation" DNA-binding "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in some" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in many" "Low region specificity" "Detected in all" HPA020375 Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 27: Non-specific - Gene expression" "Cluster 72: Non-specific - Transcription" "Cluster 5: NTERA-2 - Transcription" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA020375: AB_1859453" "unprognostic (3.17e-3)" "unprognostic (2.54e-1)" "unprognostic (8.40e-3)" "unprognostic (1.16e-1)" "unprognostic (6.13e-2)" "unprognostic (1.08e-3)" "unprognostic (4.28e-3)" "unprognostic (1.05e-1)" "unprognostic (4.24e-3)" "unprognostic (1.12e-1)" "unprognostic (1.02e-1)" "unprognostic (3.29e-2)" "prognostic unfavorable (2.24e-7)" "unprognostic (2.49e-2)" "unprognostic (6.05e-2)" "unprognostic (1.61e-2)" "prognostic favorable (4.11e-4)" 7.1 5.4 6.6 5.3 6.5 3.0 7.4 6.6 7.4 10.8 5.0 7.7 4.0 8.9 3.6 6.0 10.1 3.0 5.4 6.2 6.6 9.9 3.4 6.2 7.3 7.1 6.6 11.7 7.1 2.9 7.1 2.9 6.7 9.4 3.8 2.9 5.8 4.0 6.4 7.0 9.2 4.5 6.1 12.8 6.6 6.6 6.8 4.0 8.3 3.3 6.4 8.1 7.8 8.0 3.5 3.5 5.7 4.1 3.7 6.9 5.3 2.1 1.1 5.0 2.2 5.6 6.5 11.9 5.5 3.5 1.1 2.3 4.0 4.3 2.2 3.3 3.5 7.6 8.7 1.1 8.5 5.1 9.2 7.4 8.7 4.5 5.5 3.1 3.4 4.2 6.2 6.0 4.2 7.6 7.6 7.8 12.8 8.1 4.7 1.6 0.5 10.6 5.6 5.8 4.5 9.5 8.5 4.0 6.0 3.0 4.4 10.1 5.0 4.0 0.9 2.1 4.9 9.1 6.2 0.1 5.6 1.8 8.7 0.1 0.4 0.1 1.0 0.7 0.8 0.7 0.6 0.6 0.4 1.3 0.8 0.7 0.1 0.5 1.7 0.9 0.4 0.4 6.6 6.5 6.6 7.4 6.2 6.6 7.1 6.6 6.7 6.1 6.8 8.0 6.7 3.2 2.7 5.5 6.1 2.5 2.5 4.6 1.8 13.3 7.5 7.6 2.2 7.2 3.2 0.0 10.4 3.0 6.1 3.4 3.9 2.1 5.3 3.2 7.9 4.3 3.6 1.7 5.7 2.7 2.0 7.0 7.1 6.2 0.0 6.4 5.0 6.6 4.2 6.7 6.3 4.7 4.1 7.9 4.6 5.0 8.7 3.9 5.4 11.2 5.2 3.8 8.2 4.0 8.5 3.0 1.6 5.7 3.9 4.0 3.0 1.1 5.5 8.8 13.1 7.4 5.0 16.3 6.9 3.6 3.0 1.1 5.0 6.9 4.3 2.4 ZNF839 C14orf131 ENSG00000022976 "Zinc finger protein 839" A8K0R7 14 102317377-102342702 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Cell type enhanced" "Detected in many" "Early spermatids: 27.4" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in single" "Low lineage specificity" "Detected in single" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA020434 Uncertain Approved "Nucleoplasm,Plasma membrane" NA NA "Cluster 49: Eosinophils - Unknown function" "Cluster 23: Testis - Cell cycle regulation" "Cluster 14: REH - Unknown function" "Cluster 66: Spermatocytes - Spermatogenesis" "Plasma membrane" Nucleoplasm "HPA020434: AB_10669862" "unprognostic (7.83e-2)" "unprognostic (1.96e-1)" "unprognostic (2.28e-1)" "unprognostic (8.81e-2)" "unprognostic (1.49e-1)" "unprognostic (2.33e-1)" "unprognostic (6.73e-2)" "unprognostic (5.69e-2)" "unprognostic (1.85e-1)" "unprognostic (7.10e-3)" "prognostic favorable (4.57e-4)" "unprognostic (2.40e-2)" "prognostic favorable (5.00e-4)" "unprognostic (1.32e-1)" "unprognostic (2.17e-2)" "unprognostic (1.08e-1)" "unprognostic (8.21e-2)" 7.6 9.3 9.7 6.8 8.9 11.5 13.7 6.2 9.5 9.2 7.9 7.8 7.1 8.1 9.3 7.2 17.0 6.8 8.7 8.9 11.0 11.3 14.6 6.1 10.8 8.7 8.6 10.9 12.1 10.8 9.2 5.6 8.1 9.0 8.1 8.0 10.5 9.5 18.5 19.4 9.8 5.2 6.7 15.1 8.0 31.3 9.3 12.2 11.2 12.1 8.8 7.0 6.0 8.7 13.5 12.1 15.4 27.8 7.0 11.8 26.2 10.3 8.4 12.6 10.3 4.6 11.2 13.8 8.3 7.0 5.2 13.0 10.0 25.9 9.7 18.6 19.1 9.6 12.7 7.7 6.3 9.1 8.1 9.5 18.9 24.4 22.6 19.1 17.0 19.3 21.0 17.6 17.9 25.1 13.9 14.6 20.6 7.3 12.0 29.7 9.4 8.8 11.2 10.9 8.2 25.7 8.5 10.7 9.6 14.5 24.5 14.7 6.7 8.1 7.3 11.3 9.3 17.3 13.5 16.2 6.3 10.7 13.6 0.0 0.2 0.7 0.6 0.6 0.7 0.5 0.4 0.4 0.3 0.4 0.7 0.6 1.0 0.1 0.1 0.6 0.6 0.1 9.7 8.9 6.2 9.5 8.9 11.0 8.7 8.6 8.1 6.7 9.3 8.7 4.6 0.0 10.0 12.1 4.1 3.1 2.6 2.2 2.8 7.6 6.7 7.1 1.9 7.2 3.7 11.0 8.4 6.3 6.5 3.3 11.7 2.9 27.4 6.1 4.3 3.5 1.2 7.4 7.9 2.8 3.1 4.0 5.6 4.5 3.8 10.6 4.6 4.7 3.1 3.3 7.8 5.7 4.1 2.2 1.5 3.8 5.0 3.5 3.6 3.7 1.9 6.9 1.0 5.0 8.2 2.8 1.6 4.1 4.5 2.5 5.3 7.0 7.9 9.6 0.0 3.6 3.3 19.9 11.6 3.7 2.6 5.6 4.5 5.7 5.4 1.5 ZSWIM1 "C20orf162, dJ337O18.5" ENSG00000168612 "Zinc finger SWIM-type containing 1" Q9BR11 20 45881227-45885266 "Predicted intracellular proteins" "Evidence at protein level" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in many" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" "HPA041147, HPA046751" Uncertain Approved "Plasma membrane,Cytosol" NA NA "Cluster 5: Granulocytes - Unknown function" "Cluster 13: Striated muscle - Muscle contraction" "Cluster 8: SK-BR-3 - Unknown function" "Cluster 62: Horizontal cells - Visual perception" "Plasma membrane, Cytosol" "HPA041147: AB_2677329, HPA046751: AB_2679785" "unprognostic (6.27e-2)" "unprognostic (1.03e-1)" "unprognostic (1.87e-1)" "unprognostic (1.51e-2)" "unprognostic (1.69e-2)" "unprognostic (1.95e-1)" "prognostic unfavorable (5.47e-4)" "unprognostic (9.06e-2)" "unprognostic (1.18e-1)" "unprognostic (1.02e-1)" "prognostic favorable (1.77e-4)" "unprognostic (1.78e-1)" "unprognostic (2.77e-2)" "unprognostic (1.21e-1)" "unprognostic (2.78e-1)" "unprognostic (4.64e-1)" "unprognostic (4.29e-2)" 3.0 4.1 2.7 3.7 2.6 6.0 3.5 4.6 2.9 3.1 2.7 4.1 4.6 3.4 3.5 3.5 4.2 3.2 4.9 2.7 2.5 3.6 1.9 3.3 5.0 2.6 2.7 5.8 4.2 4.9 1.1 4.0 2.5 4.1 3.5 8.2 4.9 3.4 15.9 6.5 4.4 3.5 1.9 4.6 4.3 3.8 2.9 3.9 4.5 5.1 4.9 3.4 1.4 3.1 7.2 8.6 6.4 7.8 11.2 6.3 6.5 4.8 5.9 10.2 9.3 19.5 8.4 8.4 13.9 6.7 11.2 17.0 10.1 12.9 7.7 3.4 6.1 10.7 11.5 14.0 6.8 9.2 10.9 9.2 10.6 8.6 8.2 7.8 7.9 7.3 9.8 6.7 6.0 20.8 10.0 7.9 3.6 8.1 9.7 7.8 9.1 6.0 6.7 10.1 8.6 5.5 16.2 24.0 5.8 5.7 14.6 7.2 7.0 11.5 7.3 6.4 7.0 6.6 5.0 8.2 9.2 6.8 6.0 2.4 1.4 3.6 0.5 1.8 0.3 2.4 1.7 0.7 0.7 2.2 2.3 2.1 1.6 0.6 1.8 2.2 1.4 0.8 2.7 2.6 4.6 2.9 2.7 2.5 2.6 2.7 2.5 1.9 2.9 3.1 0.8 3.2 2.7 0.7 1.4 1.1 2.4 2.4 2.2 3.0 0.8 0.5 5.7 4.3 1.2 0.0 0.0 2.9 0.3 4.2 3.9 2.4 0.6 1.1 1.7 1.7 2.4 4.4 0.8 3.8 2.8 1.9 4.1 1.5 3.8 2.5 2.5 2.1 1.7 6.7 0.9 2.8 2.0 1.4 1.9 0.7 3.4 0.7 0.0 0.0 1.8 1.6 1.0 0.0 0.8 3.3 3.7 1.5 0.5 1.6 2.4 1.2 0.4 3.8 0.0 2.0 1.8 1.0 2.0 1.4 1.6 2.3 1.8 3.6 3.0 2.0 ZSWIM8 "4832404P21Rik, KIAA0913" ENSG00000214655 "Zinc finger SWIM-type containing 8" A7E2V4 10 73785606-73801797 "Predicted intracellular proteins" "Ubl conjugation pathway" "Evidence at protein level" "Evidence at transcript level" "Evidence at protein level" "Evidence at protein level" "Low tissue specificity" "Detected in all" "Low cell type specificity" "Detected in many" "Low cancer specificity" "Detected in all" "Low region specificity" "Detected in all" "Low immune cell specificity" "Detected in many" "Low lineage specificity" "Detected in all" "Low cell line specificity" "Detected in all" "Low region specificity" "Detected in all" "Low region specificity" "Detected in all" HPA041244 Approved Approved "Plasma membrane,Cytosol" NA NA "Cluster 46: Basophils - DNA binding" "Cluster 35: Non-specific - Unknown function" "Cluster 19: HEK293 & PC-3 - Transcription regulation" "Cluster 52: Non-specific - Transcription" "Plasma membrane, Cytosol" "HPA041244: AB_10794269" "unprognostic (8.83e-2)" "unprognostic (2.86e-1)" "unprognostic (2.89e-3)" "unprognostic (1.44e-1)" "unprognostic (4.00e-2)" "prognostic favorable (5.61e-4)" "unprognostic (3.11e-1)" "unprognostic (1.64e-1)" "unprognostic (2.97e-1)" "unprognostic (1.69e-1)" "unprognostic (2.24e-3)" "unprognostic (1.31e-1)" "unprognostic (1.52e-1)" "unprognostic (2.41e-1)" "unprognostic (1.98e-1)" "unprognostic (2.49e-1)" "unprognostic (2.52e-1)" 60.4 97.0 86.7 19.7 88.1 42.8 59.3 85.1 110.5 77.1 88.3 77.7 27.2 63.8 43.4 105.6 62.5 24.9 65.1 87.5 85.5 97.3 143.6 68.9 25.1 87.9 86.4 69.8 64.4 35.4 145.0 24.8 87.1 91.1 17.8 27.5 70.9 28.4 62.2 88.9 70.1 28.1 83.7 109.8 68.1 96.4 87.8 25.1 87.6 22.4 21.6 74.5 77.1 90.4 14.0 23.3 28.4 46.9 65.6 31.2 16.3 17.5 48.1 24.3 29.1 20.7 11.3 7.9 12.3 28.6 23.6 20.6 10.1 19.9 12.2 12.6 21.3 11.2 26.1 27.7 49.2 7.7 41.4 51.4 36.2 30.2 35.0 66.0 28.5 16.4 16.0 14.9 28.3 21.2 11.7 22.8 8.4 11.2 72.8 13.9 13.5 4.7 34.9 29.6 6.8 30.9 14.5 42.1 25.9 24.5 28.5 15.8 29.6 26.7 16.0 12.2 18.1 37.6 21.6 5.1 29.5 11.3 14.1 2.4 2.2 1.9 3.0 1.5 1.7 1.8 1.3 1.3 1.8 1.2 0.6 1.9 4.9 1.1 2.5 3.8 1.8 1.0 86.7 88.1 85.1 110.5 87.5 85.5 87.9 86.4 87.1 83.7 87.8 90.4 17.2 3.2 11.5 49.6 7.2 12.4 7.4 15.1 11.4 32.8 20.2 17.7 1.4 20.0 12.8 20.2 68.8 13.4 27.2 21.7 1.9 13.7 5.5 14.0 19.0 17.1 20.4 11.4 34.0 14.8 8.4 13.2 24.5 22.2 0.0 18.8 29.6 35.0 19.0 35.3 30.2 18.3 14.2 24.2 15.7 2.2 22.1 17.1 16.0 21.5 19.2 19.6 15.5 26.7 36.5 17.5 19.5 24.0 8.2 17.7 41.3 11.7 15.4 45.3 13.1 21.1 18.3 35.8 15.9 14.9 14.2 28.7 13.9 19.3 12.1 17.9